Gene Profiles: Chen YT, et al. (2012) Rhb1 regulates the expression of secreted aspartic protease 2 through the TOR signaling pathway in Candida albicans. Eukaryot Cell 11(2):168-82

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 Locus Id | Gene Name | Description
 orf19.3359  ARP8   Putative chromatin-remodeling enzyme complex protein; mutation confers hypersensitivity to toxic ergosterol analog, and to amphotericin B; rat catheter biofilm induced  
 orf19.3430    Plasma membrane-associated protein; physically interacts with TAP-tagged Nop1p  
 orf19.5235    Putative mitochondrial ribosomal protein of the large subunit; Hap43-induced; mutants are viable; protein level decreases in stationary phase  
 orf19.7547    Ortholog(s) have phosphatidylinositol-3-phosphate binding, ubiquitin-protein ligase activity, role in protein ubiquitination and cytosol, fungal-type vacuole membrane, late endosome, nucleus localization  
 orf19.1744  HEM4   Putative uroporphyrinogen III synthase; induced in high iron or elevated CO2; alkaline, Hap43-repressed  
 orf19.994    Protein of unknown function; induced by Mnl1 under weak acid stress; flow model biofilm repressed  
 orf19.5593    Predicted ORF from Assembly 19; merged with orf19.5592 in Assembly 20  
 orf19.1957  CYC3   Mitochondrial cytochrome c heme lyase; antigenic cell-wall protein; filament induced; induced on polystyrene adherence, interaction with macrophage; N-glycosylation, 2 heme-binding motifs; rat catheter, Spider biofilm induced  
 orf19.510    Protein of unknown function; Spider biofilm induced  
 orf19.5206    Putative chaperone protein; role in the assembly of box H/ACA snoRNPs and thus for pre-rRNA processing; Spider biofilm induced  
 orf19.2202    Protein of unknown function; induced by alpha pheromone in SpiderM medium  
 orf19.91    Protein of unknown function; flow model biofilm induced; Hap43-repressed  
 orf19.1050    Ortholog of S. cerevisiae : YMR087W, C. glabrata CBS138 : CAGL0J01397g, C. dubliniensis CD36 : Cd36_03920, C. parapsilosis CDC317 : CPAR2_107150 and Pichia stipitis Pignal : PICST_61741  
 orf19.2886  CEK1   ERK-family protein kinase; required for wild-type yeast-hypha switch, mating efficiency, virulence in mice; Cst20-Hst7-Cek1-Cph1 MAPK pathway regulates mating, and invasive hyphal growth under some conditions; Spider biofilm induced  
 orf19.6595  RTA4   Protein similar to S. cerevisiae Rsb1p, involved in fatty acid transport; transposon mutation affects filamentous growth; alkaline downregulated; caspofungin induced; possibly an essential gene; Hap43p-repressed  
 orf19.4599  PHO89   Putative phosphate permease; transcript regulated upon white-opaque switch; alkaline induced by Rim101; possibly adherence-induced; F-12/CO2 model, rat catheter and Spider biofilm induced  
 orf19.3908    Protein of unknown function; Spider biofilm induced  
 orf19.2064    Putative transcription factor with zinc finger DNA-binding motif  
 orf19.711    Protein of unknown function; induced by nitric oxide; predicted ORF from Assembly 19; removed from Assembly 20; restored based on transcription data  
 orf19.4608  PDC12   Putative pyruvate decarboxylase; fungal-specific (no human or murine homolog)  
 orf19.7317  UGA33   Zinc-finger transcription factor; similar to S. cerevisiae Uga3 which regulates gamma-aminobutyrate metabolism gene expression; required for yeast cell adherence to silicone substrate; rat catheter biofilm induced  
 orf19.1587  HGT20   Putative glucose transporter of the major facilitator superfamily; the C. albicans glucose transporter family comprises 20 members; 12 probable membrane-spanning segments; regulated by Nrg1  
 orf19.5980    Protein of unknown function; Hap43-repressed gene  
 orf19.1412    Ortholog of C. dubliniensis CD36 : Cd36_44020, C. parapsilosis CDC317 : CPAR2_302330, Candida tenuis NRRL Y-1498 : CANTEDRAFT_105448 and Debaryomyces hansenii CBS767 : DEHA2C10582g  
 orf19.6048    Protein of unknown function; Spider biofilm induced  
 orf19.7043    Ortholog(s) have endoplasmic reticulum localization  
 orf19.5129    Ortholog of C. dubliniensis CD36 : Cd36_72910, C. parapsilosis CDC317 : CPAR2_704100, Candida tenuis NRRL Y-1498 : CANTEDRAFT_113193 and Debaryomyces hansenii CBS767 : DEHA2E23100g  
 orf19.1406    Ortholog(s) have DNA-directed DNA polymerase activity, role in error-free translesion synthesis, error-prone translesion synthesis and mitochondrion, nuclear chromatin, zeta DNA polymerase complex localization  
 orf19.1756  GPD1   Glycerol-3-phosphate dehydrogenase; glycerol biosynthesis; regulated by Efg1; regulated by Tsa1, Tsa1B under H2O2 stress conditions; Sflow model and Spider biofilm induced  
 orf19.2519    Ortholog(s) have role in chromosome segregation and nuclear MIS12/MIND complex localization  
 orf19.3615    Protein of unknown function; induced in core caspofungin response; expression upregulated in an ssr1 null mutant; induced by nitric oxide independent of Yhb1p  
 orf19.1043    Ortholog(s) have lysophosphatidic acid acyltransferase activity and role in cellular response to cadmium ion, cellular triglyceride homeostasis, detoxification of cadmium ion, lipid particle organization, protein targeting to vacuole  
 orf19.4914    Ortholog(s) have role in response to DNA damage stimulus  
 orf19.1757    Putative C2H2 transcription factor; expression upregulated in clinical isolates from HIV+ patients with oral candidiasis; Spider biofilm induced  
 orf19.1422  FZO1   Mitochondrial biogenesis protein; rat catheter and Spider biofilm induced  
 orf19.6966    Ortholog(s) have choline kinase activity, ethanolamine kinase activity, role in phosphatidylcholine biosynthetic process, phosphatidylethanolamine biosynthetic process and cytosol, nucleus localization  
 orf19.1367  MTW1   Kinetochore component; amount of Nuf2p and Mtw1p protein detected at each centromere is consistent with a single kinetochore microtubule attachment site  
 orf19.2125    Protein of unknown function; GlcNAc-induced protein; Spider biofilm induced; rat catheter biofilm repressed  
 orf19.6605    Ortholog(s) have fungal-type vacuole, mitochondrion localization  
 orf19.1296    Ortholog(s) have role in spliceosomal snRNP assembly and U4/U6 x U5 tri-snRNP complex, mitochondrion localization  
 orf19.2516    Has domain(s) with predicted role in cell redox homeostasis  
 orf19.1655  PXP2   Putative acyl-CoA oxidase; enzyme of fatty acid beta-oxidation; induced during macrophage infection; opaque specific transcript; putative peroxisome targeting signal; Spider biofilm induced  
 orf19.1706  MET18   Putative protein with a predicted role in nucleotide excision repair (NER) and RNA polymerase II (RNAP II) transcription; Plc1p-regulated  
 orf19.4903    Ortholog(s) have endoplasmic reticulum localization  
 orf19.1719  SGA1   Putative glucoamylase; induced in oralpharyngeal candidasis; rat catheter and Spider biofilm induced  
 orf19.1209    Predicted ORF from Assembly 19; merged with orf19.4557 in Assembly 20  
 orf19.1225  PEX22   Putative peroxin  
 orf19.1202    Ortholog of C. dubliniensis CD36 : Cd36_60350, C. parapsilosis CDC317 : CPAR2_603550, Candida tenuis NRRL Y-1498 : CANTEDRAFT_114325 and Debaryomyces hansenii CBS767 : DEHA2G04950g  
 orf19.3304    Exosome non-catalytic core component; involved in 3'-5' RNA processing and degradation in the nucleus and cytoplasm; Spider biofilm induced  
 orf19.1790    Predicted ORF from Assembly 19; merged with orf19.1789.1 in Assembly 20