Gene Profiles: Shapiro RS, et al. (2012) Pho85, Pcl1, and Hms1 signaling governs Candida albicans morphogenesis induced by high temperature or Hsp90 compromise. Curr Biol 22(6):461-70

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 Locus Id | Gene Name | Description
 orf19.1920    Ortholog of C. dubliniensis CD36 : Cd36_15040  
 orf19.4478    Ortholog(s) have aspartate-tRNA ligase activity, role in mitochondrial aspartyl-tRNA aminoacylation and mitochondrion localization  
 orf19.1082.1    Ortholog(s) have cytochrome-c oxidase activity, role in mitochondrial respiratory chain complex IV assembly and cytosol, mitochondrial intermembrane space, mitochondrial respiratory chain complex IV, nucleus localization  
 orf19.6925  HTB1   Histone H2B; induced by adherence to polystyrene; amphotericin B, caspofungin repressed; flucytosine, fluconazole induced; Efg1 regulated; slow growth, increased white-to opaque switch in ectopic expression strains; Spider biofilm repressed  
 orf19.4686    Ortholog of S. cerevisiae : ESL1, C. dubliniensis CD36 : Cd36_41030, C. parapsilosis CDC317 : CPAR2_401340, Candida tenuis NRRL Y-1498 : CANTEDRAFT_104645 and Debaryomyces hansenii CBS767 : DEHA2E18766g  
 orf19.646  GLN1   Putative glutamate synthase; regulated by Tsa1, Tsa1B under H2O2 stress conditions; Spider biofilm induced  
 orf19.3870  ADE13   Adenylosuccinate lyase; enzyme of adenine biosynthesis; soluble protein in hyphae; not induced during GCN response, in contrast to the S. cerevisiae ortholog; repressed by nitric oxide  
 orf19.4623.3  NHP6A   Putative non-histone chromatin component; RNA abundance regulated by tyrosol,cell density; Hap43-induced; amphotericin B, caspofungin repressed; 5'-UTR intron; rat catheter and Spider biofilm repressed  
 orf19.1354  UCF1   Upregulated by cAMP in filamentous growth; induced in high iron, decreased upon yeast-hypha switch; downregulation correlates with clinical fluconazole resistance; Ras1-regulated; Hap43-repressed; flow model biofilm induced  
 orf19.5960  NCE102   Non classical protein export protein; localized to plasma membrane; Hap43-induced gene; flow model biofilm induced; Spider biofilm induced  
 orf19.1853  HHT2   Putative histone H3; farnesol regulated; Hap43-induced; rat catheter and Spider biofilm repressed  
 orf19.1051  HTA2   Putative histone H2A; farnesol regulated; rat catheter biofilm repressed; Spider biofilm repressed; Hap43-induced  
 orf19.3789  RPL24A   Predicted ribosomal protein; downregulated upon phagocytosis by murine macrophage; intron in 5'-UTR; Hap43-induced; Spider biofilm repressed  
 orf19.2690    Putative mitochondrial GTPase; required for mitochondrial morphology and genome maintenance; Spider biofilm induced  
 orf19.4941  TYE7   bHLH transcription factor; control of glycolysis; required for biofilm formation; hyphally regulated by Cph1, Cyr1; flucytosine, Hog1 induced; amphotericin B, caspofungin repressed; induced in flow model biofilm and planktonic cultures  
 orf19.4085    Protein of unknown function; transcript detected on high-resolution tiling arrays  
 orf19.3388    Predicted ORF from Assembly 19; removed from Assembly 20  
 orf19.4789    Has domain(s) with predicted metal ion binding activity  
 orf19.285    Ortholog of S. cerevisiae Igo2; role in mRNA stabilization of mRNA; Spider biofilm induced  
 orf19.1049    Predicted NUDIX hydrolase domain; Hap43-induced  
 orf19.7495    Protein with NADPH oxidoreductase containing flavin mononucleotide (FMN) domain; induced by nitric oxide  
 orf19.4850    Ortholog(s) have cytosol, nucleus localization  
 orf19.6638  PTC4   Type PP2C serine/threonine phosphatase; localized to mitochondria; mutation causes sensitivity to sodium, potassium and azole drugs; decreased expression in hyphae compared to yeast-form cells  
 orf19.1011  MNN21   Ortholog(s) have alpha-1,2-mannosyltransferase activity, role in cell wall mannoprotein biosynthetic process and Golgi apparatus localization  
 orf19.48  RPM2   Mitochondrial RNase P subunit; roles in nuclear transcription, cytoplasmic and mitochondrial RNA processing, mitochondrial translation; virulence-group-correlated expression; likely essential (UAU1 method); rat catheter biofilm induced  
 orf19.1606    Protein of unknown function; Plc1-regulated  
 orf19.2646  ZCF13   Predicted Zn(II)2Cys6 transcription factor; similar to but not the true ortholog of S. cerevisiae Hap1; mutants display decreased colonization of mouse kidneys  
 orf19.2428.2    ORF Predicted by Annotation Working Group; removed from Assembly 20; rat catheter biofilm induced  
 orf19.4066    Putative glycerol-3-phosphate acyltransferase; Hog1-repressed  
 orf19.2060  SOD5   Cu and Zn-containing superoxide dismutase; protects against oxidative stress; induced by neutrophils, hyphal growth, caspofungin, osmotic/oxidative stress; oralpharyngeal candidiasis induced; rat catheter and Spider biofilm induced  
 orf19.4936.1    Putative adhesin-like protein; Spider biofilm induced  
 orf19.6244    Ortholog of C. dubliniensis CD36 : Cd36_06250, C. parapsilosis CDC317 : CPAR2_206820, Candida tenuis NRRL Y-1498 : CANTEDRAFT_125137 and Debaryomyces hansenii CBS767 : DEHA2G13266g  
 orf19.6704    Protein of unknown function; Hap43-repressed gene  
 orf19.7379  FAA2   Putative acyl CoA synthetase; expression regulated upon white-opaque switch; rat catheter biofilm induced; Spider biofilm induced  
 orf19.1814  STT4   Putative phosphatidylinositol-4-kinase  
 orf19.6895    Predicted ORF from Assembly 19; merged with orf19.5204 in Assembly 20  
 orf19.4424  PHO100   Putative inducible acid phosphatase; DTT-extractable and observed in culture supernatant in low-phosphate conditions; slight effect on murine virulence; virulence-group-correlated expression; N-glycosylated; F-12/CO2 early biofilm induced  
 orf19.3280    Ortholog of Candida albicans WO-1 : CAWG_01435  
 orf19.2882  XUT1   Putative high-affinity, high-capacity xanthine-uric acid/H+ symporter; similar to A. nidulans UapA; member of the Nucleobase-Ascorbate Transporter/Nucleobase-Cation Symporter (NAT/NCS2) family; rat catheter biofilm induced  
 orf19.7121    Protein of unknown function; Spider biofilm repressed  
 orf19.1969  CCW14   Putative mannoprotein of cell wall with role in response to stress; increased mRNA abundance observed in cyr1 homozygous mutant (hyphal or yeast-form cells) and in ras1 homozygous mutant (yeast-form cells)  
 orf19.644  HGT9   Putative glucose transporter of the major facilitator superfamily; the C. albicans glucose transporter family comprises 20 members; 12 probable membrane-spanning segments; induced at low (0.2%, compared to 2%) glucose in rich media; intron  
 orf19.150  TIM17   Predicted component of the Translocase of the Inner Mitochondrial membrane (TIM23 complex), involved in protein import into mitochondria  
 orf19.4160    Ortholog(s) have serine-type endopeptidase activity, role in glycoprotein metabolic process, mitochondrial tRNA threonylcarbamoyladenosine modification and mitochondrion localization  
 orf19.6284    Ortholog(s) have GTP binding, signal recognition particle binding activity, role in protein targeting to ER and integral to endoplasmic reticulum membrane localization  
 orf19.3205  MPRL36   Mitochondrial ribosomal protein of the large subunit; rat catheter biofilm induced  
 orf19.5977  CEM1   Protein similar to S. cerevisiae Cem1p, an acyl carrier protein involved in fatty acid biosynthesis; likely to be essential for growth, based on an insertional mutagenesis strategy  
 orf19.7298  CHS2   Chitin synthase; nonessential; required for wild-type chitin deposition in hyphae; transcript regulated during dimorphic transition; Chs1 and Chs2, but not Chs3, are inhibited by the protoberberine HWY-289; flow model biofilm repressed  
 orf19.3220    Putative rRNA processing protein; Spider biofilm induced  
 orf19.2032    Protein of unknown function; rat catheter biofilm induced