Gene Profiles: Fanning S, et al. (2012) Functional control of the Candida albicans cell wall by catalytic protein kinase A subunit Tpk1. Mol Microbiol 86(2):284-302
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 Locus Id | Gene Name | Description
 orf19.7622  SPT3   Functional homolog of S. cerevisiae Spt3p; required for virulence in mouse systemic infection; homozygous null mutant is hyperfilamentous  
 orf19.6180    Protein similar to Pichia anomala YDL054c and S. cerevisiae Ydl054cp; transmembrane regions predicted; Hap43p-repressed gene  
 orf19.295    Ortholog of C. dubliniensis CD36 : Cd36_82970, Lodderomyces elongisporus NRLL YB-4239 : LELG_02117, Debaryomyces hansenii CBS767 : DEHA2G01012g and Candida lusitaniae ATCC 42720 : CLUG_03529  
 orf19.281    Ortholog of C. dubliniensis CD36 : Cd36_82880, C. parapsilosis CDC317 : CPAR2_102370, Candida tenuis NRRL Y-1498 : CANTEDRAFT_118463 and Pichia stipitis Pignal : PICST_32241  
 orf19.1585  ZRT2   Zinc transporter; ciclopirox olamine, fluconazole, alkaline repressed; transcript induced by amphotericin B, interaction with macrophages; possibly essential (UAU1 method); induced in oralpharyngeal candidiasis; Spider biofilm induced  
 orf19.7091    Protein of unknown function; induced by nitric oxide; Spider biofilm repressed  
 orf19.3008  COQ4   Protein with a putative role in coenzyme Q biosynthesis; transcriptionally induced by interaction with macrophage; Hap43p-repressed gene  
 orf19.7563  BET2   Putative Type II geranylgeranyltransferase beta subunit; transcript regulated by Mig1  
 orf19.5673  OPT7   Putative oligopeptide transporter; possibly transports GSH or related compounds; Hog1-induced; expression of OPT6, -7, or -8 does not suppress defect of mutant lacking OPT1-3; Hap43-repressed; F-12/CO2 early biofilm induced  
 orf19.6690    Protein of unknown function; Hap43-repressed gene  
 orf19.1979  GIT3   Glycerophosphocholine permease; white cell specific transcript; fungal-specific; alkaline repressed; caspofungin, macrophage/pseudohyphal-repressed; flow model biofilm induced; Spider biofilm induced  
 orf19.6268    Putative cohesin complex subunit; expression downregulated in an ssr1 null mutant  
 orf19.1371    Ortholog of C. dubliniensis CD36 : Cd36_23880, C. parapsilosis CDC317 : CPAR2_806590, Candida tenuis NRRL Y-1498 : CANTEDRAFT_92769 and Debaryomyces hansenii CBS767 : DEHA2B13376g  
 orf19.4720  CTR2   Putative low-affinity copper transporter of the vacuolar membrane; induced by nitric oxide; clade-associated gene expression; rat catheter and flow model biofilm induced  
 orf19.3404    Protein of unknown function; transcription repressed by fluphenazine treatment  
 orf19.4116    Ortholog(s) have N-acetyltransferase activity, role in response to drug and nuclear envelope, plasma membrane localization  
 orf19.1780    Has domain(s) with predicted catalytic activity  
 orf19.4750    Ortholog of C. dubliniensis CD36 : Cd36_08410, C. parapsilosis CDC317 : CPAR2_301700, Candida tenuis NRRL Y-1498 : cten_CGOB_00267 and Debaryomyces hansenii CBS767 : DEHA2C10560g  
 orf19.381    Predicted ORF from Assembly 19; merged with orf19.2661 in Assembly 20  
 orf19.2962    Protein of unknown function; Spider biofilm induced  
 orf19.3538  FRE9   Ferric reductase; alkaline induced; ciclopirox olamine; Hap43-induced  
 orf19.1693  CAS4   RAM cell wall integrity signaling network protein; cell separation, azole sensitivity; needed for hyphal growth; insertion mutation near 3' end of gene increases caspofungin sensitivity; pheromone/hyphal induced; flow biofilm repressed  
 orf19.5180  PRX1   Thioredoxin peroxidase; transcriptionally induced by interaction with macrophage; fluconazole induced; Fkh2p-downregulated; caspofungin repressed; protein present in exponential and stationary growth phase yeast cultures  
 orf19.2297  ARL3   Putative Ras superfamily GTPase; induced by nitric oxide independent of Yhb1p  
 orf19.4872    Protein of unknown function; induced by Mnl1 under weak acid stress; Hap43-induced; mutant is viable  
 orf19.4316    Trimethyllysine dioxygenase, the first enzyme in the carnitine biosynthesis pathway; hypha-induced expression, regulated by Cyr1, Ras1, Efg1; rat catheter biofilm repressed  
 orf19.5519  GCV1   Putative T subunit of glycine decarboxylase; transcript negatively regulated by Sfu1; Spider biofilm repressed  
 orf19.385  GCV2   Glycine decarboxylase P subunit; protein of glycine catabolism; repressed by Efg1; Hog1-induced; induced by Rim101 at acid pH; transcript induced in elevated CO2; stationary phase enriched protein  
 orf19.3548    Ortholog(s) have mitochondrion localization  
 orf19.2971    Ortholog of C. dubliniensis CD36 : Cd36_02630, C. parapsilosis CDC317 : CPAR2_108390, Candida tenuis NRRL Y-1498 : CANTEDRAFT_115724 and Debaryomyces hansenii CBS767 : DEHA2D07986g  
 orf19.1667    Protein with a predicted SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily domain; Hap43-repressed gene  
 orf19.1345  LIP8   Secreted lipase, member of a differentially expressed lipase gene family with possible roles in nutrition and/or in creating an acidic microenvironment; LIP5 and LIP8 are expressed at all stages of both mucosal and systemic infection  
 orf19.4685    Dubious open reading frame  
 orf19.3063  HFL1   HAP5-like; ortholog of S. cerevisiae Dpb3; third-largest subunit of DNA polymerase II (DNA polymerase epsilon); phosphorylated protein; mutants have a growth defect  
 orf19.3519  SUA72   Predicted transcription factor; induced during planktonic growth, whereas related SUA71 is downregulated  
 orf19.6222  SPO22   Ortholog(s) have role in regulation of synaptonemal complex assembly and condensed nuclear chromosome localization  
 orf19.7357    Ortholog(s) have role in coenzyme A biosynthetic process and cytosol, nucleus localization  
 orf19.3487    Ortholog of C. dubliniensis CD36 : Cd36_33330, C. parapsilosis CDC317 : CPAR2_701980, Debaryomyces hansenii CBS767 : DEHA2C15840g and Pichia stipitis Pignal : PICST_31066  
 orf19.7477  YRB1   Functional homolog of S. cerevisiae Yrb1p; regulates Gsp1 GTPase activity and thereby affects nucleocytoplasmic transport and cytoskeletal dynamics; transcript is not regulated by white-opaque switch or by dimorphic transition  
 orf19.1170  ARO7   Putative chorismate mutase; fungal-specific (no human or murine homolog); alkaline upregulated  
 orf19.4076  MET10   Sulfite reductase; role in sulfur amino acid metabolism; induced by human whole blood or PMNs; Hog1-induced; possibly adherence-induced; flow model, Spider model, F-12/CO2 biofilm induced  
 orf19.2618  MET2   Homoserine acetyltransferase; Hap43p-, Gcn4p-regulated; macrophage/pseudohyphal-repressed; not highly biofilm induced, in contrast to many sulfur amino acid metabolic genes; no human or murine homolog; virulence-group-correlated expression  
 orf19.6189    Chalcone related protein family; flow model biofilm induced  
 orf19.1177    Ortholog of S. cerevisiae Rtt106; histone chaperone that regulates chromatin structure in transcribed and silenced chromosomal regions; affects transcriptional elongation; Hap43-repressed; Spider biofilm repressed  
 orf19.4581    Putative glycosylphosphatidylinositol-alpha 1,4 mannosyltransferase I; regulated by Tsa1p, Tsa1Bp under H2O2 stress conditions  
 orf19.2898    Ortholog(s) have borate efflux transmembrane transporter activity, role in borate transport, protein targeting to vacuole and fungal-type vacuole, plasma membrane localization  
 orf19.1686    Ortholog(s) have mitochondrion localization  
 orf19.5838  SER2   Ortholog(s) have phosphoserine phosphatase activity, role in L-serine biosynthetic process and cytoplasm, nucleus localization  
 orf19.6938  MEU1   Putative methylthioadenosine phosphorylase; protein level decreases in stationary phase cultures  
 orf19.597    Protein with an aspartate aminotransferase domain; Gcn4-regulated