|
| Locus Id | | | Gene Name | | | Description |
 |
| orf19.2131 | | | | Ortholog(s) have ubiquitin-protein ligase activity and role in protein ubiquitination, ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway | |
 |
| orf19.3997 | | ADH1 | | Alcohol dehydrogenase; oxidizes ethanol to acetaldehyde; at yeast cell surface; immunogenic in humans/mice; complements S. cerevisiae adh1 adh2 adh3 mutant; fluconazole, farnesol-induced; flow model biofilm induced; Spider biofilm repressed | |
 |
| orf19.5280 | | MUP1 | | Putative high affinity methionine permease; alkaline upregulated by Rim101; Spider biofilm induced | |
 |
| orf19.2471 | | GIM5 | | Putative heterohexameric cochaperone prefoldin complex subunit; macrophage/pseudohyphal-repressed gene and macrophage-induced protein | |
 |
| orf19.3065 | | DAO1 | | Putative D-amino acid oxidase; transcription is regulated upon yeast-hyphal switch | |
 |
| orf19.583 | | | | Indoleamine 2,3-dioxygenase (IDO); rate-limiting enzyme of tryptophan catabolism via kynurenine; enzyme inhibition by 1-methyl-D,L-tryptophan increases hyphal growth; expressed in yeast and hyphae; rat catheter and Spider biofilm induced | |
 |
| orf19.405 | | VCX1 | | Putative H+/Ca2+ antiporter; Spider biofilm repressed | |
 |
| orf19.3967 | | PFK1 | | Phosphofructokinase alpha subinit; activated by fructose 2,6-bisphosphate, AMP, ATP inhibited; activity reduced on hyphal induction; phagocytosis-repressed; fluconazole, flow model biofilm induced; rat catheter and Spider biofilm repressed | |
 |
| orf19.203 | | STB3 | | Putative SIN3-binding protein 3 homolog; caspofungin induced; macrophage/pseudohyphal-repressed; rat catheter biofilm induced | |
 |
| orf19.3565 | | | | Ortholog of C. dubliniensis CD36 : Cd36_19830, C. parapsilosis CDC317 : CPAR2_206470, Candida tenuis NRRL Y-1498 : CANTEDRAFT_113899 and Debaryomyces hansenii CBS767 : DEHA2C05676g | |
 |
| orf19.2398 | | | | Protein of unknown function; Hap43-repressed; transcript increased in azole-resistant strain overexpressing CDR1 and CDR2; possibly regulated by Tac1; induced by Mnl1 in weak acid stress; flow model biofilm induced; Spider biofilm induced | |
 |
| orf19.1945 | | AUR1 | | Inositolphosphorylceramide (IPC) synthase; catalyzes the key step in sphingolipid biosynthesis; antifungal drug target; flow model biofilm induced; Spider biofilm induced | |
 |
| orf19.538 | | | | Ortholog(s) have role in GPI anchor biosynthetic process and glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex localization | |
 |
| orf19.5622 | | GLC3 | | Putative 1,4-glucan branching enzyme; fluconazole-induced; colony morphology-related gene regulation by Ssn6; stationary phase enriched protein | |
 |
| orf19.4654 | | | | Protein of unknown function; Spider biofilm induced | |
 |
| orf19.736 | | SRB8 | | Putative RNA polymerase II mediator complex subunit; early-stage flow model biofilm induced | |
 |
| orf19.215 | | | | Component of a complex containing the Tor2p kinase; possible a role in regulation of cell growth; Spider biofilm induced | |
 |
| orf19.805 | | | | Putative protein of unknown function; possibly mitochondrial; Hap43-repressed; Spider biofilm repressed | |
 |
| orf19.2020 | | HGT6 | | Putative high-affinity MFS glucose transporter; 20 family members; induced in core stress response; fluconazole, oralpharyngeal candidasis induced; flow model biofilm induced; Spider biofilm induced | |
 |
| orf19.9013 | | IPK1 | | | |
 |
| orf19.13177 | | | | | |
 |
| orf19.5901 | | PKC1 | | Protein kinase C; functional homolog of S. cerevisiae Pkc1p; mutant has abnormal yeast-form cell morphology and increased cell lysis; activated by phosphatidylserine; target of antifungal, cercosporamide; R400P mutant is activated | |
 |
| orf19.7710 | | | | | |
 |
| orf19.174 | | | | Predicted ORF from Assembly 19; merged with orf19.173 in Assembly 20 | |
 |
| orf19.1956 | | | | Ortholog(s) have role in reciprocal meiotic recombination and mitochondrion localization | |
 |
| orf19.211 | | | | Predicted homeodomain-like transcription factor; also has a metal-binding Ada DNA repair protein domain; Spider biofilm induced | |
 |
| orf19.1467 | | COX13 | | Cytochrome c oxidase; flucytosine induced; repressed by nitric oxide | |
 |
| orf19.3414 | | SUR7 | | Protein required for normal cell wall, plasma membrane, cytoskeletal organization, endocytosis; localizes to eisosome subdomains of plasma membrane; four transmembrane motifs; mutant shows ectopic, chitin-rich cell wall; fluconazole-induced | |
 |
| orf19.5288 | | IFE2 | | Putative alcohol dehydrogenase; yeast-enriched transcript; Efg1-regulated; induced by prostaglandins, Hog1, fluconazole; rat catheter biofilm induced | |
 |
| orf19.3041 | | | | Ortholog(s) have ubiquitin protein ligase binding activity | |
 |
| orf19.6881 | | YTH1 | | Putative mRNA cleavage and polyadenylation specificity factor; transcription is regulated upon yeast-hyphal switch; decreased expression in hyphae compared to yeast-form cells; fluconazole or flucytosine induced | |
 |
| orf19.2666 | | | | Predicted ORF from Assembly 19; merged with orf19.2665 in Assembly 20 | |
 |
| orf19.1788 | | | | Predicted ORF from Assembly 19; merged with orf19.1290 in Assembly 20 | |
 |
| orf19.8185 | | PDX3 | | | |
 |
| orf19.5159 | | DUG3 | | Putative glutamine amidotransferase (GATase II); role in glutathione catabolism; | |
 |
| orf19.1193 | | GNP1 | | Similar to asparagine and glutamine permease; fluconazole, caspofungin induced; regulated by Nrg1, Mig1, Tup1, Gcn2, Gcn4, and alkaline regulated by Rim101; repressed during chlamydospore formation; rat catheter, flow model biofilm induced | |
 |
| orf19.5079 | | CDR4 | | Putative ABC transporter superfamily; fluconazole, Sfu1, Hog1, core stress response induced; caspofungin repressed; fluconazole resistance not affected by mutation or correlated with expression; rat catheter and flow model biofilm induced | |
 |
| orf19.4792 | | | | Protein with a regulator of G-protein signaling domain; Plc1-regulated; Spider biofilm induced; rat catheter biofilm repressed | |
 |
| orf19.7022 | | | | Ortholog of C. dubliniensis CD36 : Cd36_70850, Candida tenuis NRRL Y-1498 : cten_CGOB_00183, Debaryomyces hansenii CBS767 : DEHA2F22462g and Pichia stipitis Pignal : PICST_60416 | |
 |
| orf19.1267 | | | | Ortholog of S. cerevisiae : CAJ1, C. glabrata CBS138 : CAGL0L00957g, C. dubliniensis CD36 : Cd36_45380, C. parapsilosis CDC317 : CPAR2_500650 and Candida tenuis NRRL Y-1498 : CANTEDRAFT_132273 | |
 |
| orf19.4077 | | MIT1 | | Mannosylinositol phosphorylceramide (MIPC) synthase catalytic subunit; sphingolipid biosynthesis; fluconazole, caspofungin induced; macrophage-repressed; Spider biofilm induced | |
 |
| orf19.4698 | | PTC8 | | Predicted type 2C protein phosphatase, ser/thr-specific; required for hyphal growth; transcript induced by stress; flow model biofilm induced; Spider biofilm induced | |
 |
| orf19.2609 | | CET1 | | mRNA 5'-triphosphatase; large subunit of mRNA capping enzyme; positively regulates Ceg1 activity; functional homolog of S. cerevisiae Cet1; Cet1 and Cgt1 form a 2:1 complex; flow model biofilm induced | |
 |
| orf19.2965 | | | | Putative guanyl-nucleotide exchange factor; Spider biofilm repressed | |
 |
| orf19.745 | | VAC8 | | Protein involved in vacuolar inheritance; required for hyphal growth; contains armadillo repeats | |
 |
| orf19.1715 | | IRO1 | | Putative transcription factor; role in iron utilization, pathogenesis; both IRO1 and adjacent URA3 are mutated in strain CAI4; suppresses S. cerevisiae aft1 mutant low-iron growth defect; hyphal-induced; reports differ about iron regulation | |
 |
| orf19.2785 | | ATP7 | | Putative subunit of the F1F0-ATPase complex; colony morphology-related gene regulation by Ssn6; farnesol, macrophage-downregulated protein abundance; protein present in exponential and stationary yeast growth phases; Hap43-induced | |
 |
| orf19.8937 | | FCY21 | | | |
 |
| orf19.2685 | | PGA54 | | GPI-anchored protein; Hog1-repressed; induced in cyr1 or efg1 mutant or in hyphae; colony morphology-related gene regulation by Ssn6; induced in RHE model; mRNA binds She3; regulated in Spider biofilms by Tec1, Egf1, Ntd80, Rob1, Brg1 | |
 |
| orf19.173 | | | | C2H2 transcription factor; induced by Mnl1 under weak acid stress | |