Gene Profiles: Pande K, et al. (2013) Passage through the mammalian gut triggers a phenotypic switch that promotes Candida albicans commensalism. Nat Genet 45(9):1088-91

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 Locus Id | Gene Name | Description
 orf19.2733    Putative subunit of phosphatidylinositol 3-kinase complexes I and II; transcription is activated in the presence of elevated CO2  
 orf19.4656    Ortholog of C. dubliniensis CD36 : Cd36_41300, C. parapsilosis CDC317 : CPAR2_400390, Candida tenuis NRRL Y-1498 : CANTEDRAFT_94704 and Debaryomyces hansenii CBS767 : DEHA2B02992g  
 orf19.3247    Putative ortholog of S. cerevisiae Laa1p; likely to be essential for growth, based on an insertional mutagenesis strategy  
 orf19.3699  TEP1   Putative protein phosphatase of the PTP family (tyrosine-specific), similar to S. cerevisiae Tep1p  
 orf19.7055    Dubious open reading frame  
 orf19.1967    Ortholog(s) have structural constituent of ribosome activity and mitochondrial large ribosomal subunit localization  
 orf19.1286    Ortholog of Candida albicans WO-1 : CAWG_04776  
 orf19.3615    Protein of unknown function; induced in core caspofungin response; expression upregulated in an ssr1 null mutant; induced by nitric oxide independent of Yhb1p  
 orf19.2647  ZCF14   Putative Zn(II)2Cys6 transcription factor; caspofungin induced  
 orf19.6934    Ortholog(s) have role in protein insertion into mitochondrial membrane from inner side and integral to mitochondrial inner membrane localization  
 orf19.2382    Protein similar to isoleucyl-tRNA synthetase; isoleucyl-tRNA synthetase is the target of drugs including the cyclic beta-amino acid icofungipen/PLD-118/BAY-10-8888 and mupirocin  
 orf19.7619    Protein with a mitochondrial distribution and morphology domain; possibly an essential gene, disruptants not obtained by UAU1 method; rat catheter and Spider biofilm induced  
 orf19.3499    Secreted potein; Hap43-repressed; fluconazole-induced; regulated by Tsa1, Tsa1B under H2O2 stress conditions; induced by Mnl1p under weak acid stress; Spider biofilm induced  
 orf19.6249  HAK1   Putative potassium transporter; similar to Schwanniomyces occidentalis Hak1p; amphotericin B induced; induced upon phagocytosis by macrophage; Hap43-repressed; rat catheter biofilm repressed  
 orf19.7320  LIP7   Probable lipase, part of a gene family whose members are differentially expressed during infection; lacks a signal sequence for secretion, unlike other family members; may have a role in nutrition or in creating an acidic microenvironment  
 orf19.3544    Putative protein of unknown function; Hap43p-repressed gene  
 orf19.5121  OPT5   Oligopeptide transporter; fungal-specific (no human or murine homolog); induced by BSA, but not by tetrapeptide or pentapeptide  
 orf19.2768  AMS1   Putative alpha-mannosidase; transcript regulated by Nrg1; induced during cell wall regeneration; flow model biofilm induced; Spider biofilm induced  
 orf19.6489  FMP45   Predicted membrane protein induced during mating; mutation confers hypersensitivity to toxic ergosterol analog, to amphotericin B; alkaline repressed; repressed by alpha pheromone in SpiderM medium; rat catheter, Spider biofilm induced  
 orf19.4682  HGT17   Putative MFS family glucose transporter; 20 members in C. albicans; 12 probable membrane-spanning segments; induced at low (0.2%, compared to 2%) glucose in rich media; Spider biofilm induced  
 orf19.4970    Protein of unknown function; Spider biofilm induced  
 orf19.2552    Protein similar to S. cerevisiae Pmr1p; amphotericin B induced; previously merged with orf19.2553; unmerged from orf19.2553 in a revision of Assembly 21  
 orf19.1606    Protein of unknown function; Plc1-regulated  
 orf19.7597  PGA12   Putative GPI-anchored protein  
 orf19.4873    Protein of unknown function; transcript regulated by white-opaque switch; flow model biofilm induced; Spider biofilm induced  
 orf19.6023    Protein with a predicted multidrug transporter domain; Hap43-repressed gene  
 orf19.2505    Ortholog of Candida albicans WO-1 : CAWG_02437  
 orf19.7303    Ortholog of C. dubliniensis CD36 : Cd36_34495, Candida tropicalis MYA-3404 : CTRG_05947 and Candida albicans WO-1 : CAWG_02181  
 orf19.2249    Putative metalloprotease of the mitochondrial inner membrane; expression downregulated in an ssr1 null mutant  
 orf19.5496  AVT1   Putative vacuolar transporter; promoter bound by a1p and alpha2p by ChIP-chip analysis  
 orf19.5428    Putative Golgi membrane protein with a predicted role in manganese homeostasis; Hap43p-repressed gene; clade-associated gene expression  
 orf19.3950  MSM1   Mitochondrial methionyl-tRNA synthetase (MetRS); functionally complements methionine auxotrophy of an E. coli MetRS mutant; transcript regulated by Nrg1; flow model biofilm induced  
 orf19.1202    Ortholog of C. dubliniensis CD36 : Cd36_60350, C. parapsilosis CDC317 : CPAR2_603550, Candida tenuis NRRL Y-1498 : CANTEDRAFT_114325 and Debaryomyces hansenii CBS767 : DEHA2G04950g  
 orf19.3923  PGA37   Putative GPI-anchored protein; Hap43-repressed; Spider biofilm induced  
 orf19.1805  PEX14   Ortholog(s) have peroxisome matrix targeting signal-1 binding, peroxisome matrix targeting signal-2 binding, protein binding, bridging activity  
 orf19.6286    Ortholog(s) have role in vacuolar transport and endosome localization  
 orf19.5616    Ortholog of C. dubliniensis CD36 : Cd36_63740, C. parapsilosis CDC317 : CPAR2_503850, Pichia stipitis Pignal : PICST_32045 and Candida guilliermondii ATCC 6260 : PGUG_00070  
 orf19.134    Protein of unknown function; overlaps retrotransposon Tca13; ciclopirox olamine induced  
 orf19.90    Ortholog(s) have cytoplasm localization  
 orf19.1946    Similar to an aldose 1-epimerase-related protein; antigenic during murine systemic infection; protein present in exponential and stationary phase yeast cultures; Hap43-induced; Spider biofilm repressed  
 orf19.4609    Putative dienelactone hydrolase; protein abundance is affected by URA3 expression in the CAI-4 strain background; protein present in exponential and stationary growth phase yeast cultures; rat catheter biofilm repressed  
 orf19.3752  RAD51   Protein involved in homologous recombination and DNA repair; flucytosine induced; slow growth and increased white-to-opaque switching frequency in null mutant  
 orf19.3734  GEF2   Member of the voltage chloride channel family; Hap43p-repressed gene  
 orf19.5213.1  COX8   Putative cytochrome c oxidase; flucytosine induced; caspofungin repressed  
 orf19.6789    S. cerevisiae ortholog Nud1 is a spindle pole body outer plaque component; it acts through the mitotic exit network to specify asymmetric spindle pole body inheritance; Hap43-induced gene  
 orf19.7093  HGT13   Predicted sugar transporter, involved in glycerol utilization; member of the major facilitator superfamily; 12 transmembrane; gene has intron; oxidative stress-induced via Cap1p; expressed in rich medium, 2% glucose  
 orf19.3483    Putative phosphatidyl glycerol phospholipase C; Plc1-regulated; flow model biofilm induced; Spider biofilm induced  
 orf19.1237  ARO9   Aromatic transaminase; Ehrlich fusel oil pathway of aromatic alcohol biosynthesis; Rim101-dependent pH-regulation (alkaline induced); Hap43-induced gene  
 orf19.7411  OAC1   Putative mitochondrial inner membrane transporter; rat catheter biofilm induced  
 orf19.2454  PHO87   Putative phosphate permease; transcript repressed by Rim101 at pH 8; regulated by white-opaque switch; caspofungin repressed; virulence-group-correlated expression; flow model biofilm induced