ARG100 ORF ARG100 CAF0006874 PMID: 8194754|CGD_REF: CAL0080661 unknown ploidy, classical genetics unspecified Other C. albicans auxotrophy arginine C. albicans CaalfMp01 ORF COX2 CAF0007359 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient YPD medium C. albicans CaalfMp13 ORF NAD5 CAF0007389 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient YPD medium C. albicans CaalfMp14 ORF NAD4 CAF0007395 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient SLAD medium C. albicans FGR21 ORF FGR21 CAF0006879 PMID: 12773383|CGD_REF: CAL0087974 heterozygous diploid, classical genetics (haploinsufficient phenotype assay) unspecified CAI-4 filamentous growth: decreased solid Spider medium transposon insertion proximal to, but not within, the ORF C. albicans FGR36 ORF FGR36 CAF0006880 PMID: 12773383|CGD_REF: CAL0087974 heterozygous diploid, classical genetics (haploinsufficient phenotype assay) null CAI-4 viable heterozygous transposon insertion C. albicans FGR36 ORF FGR36 CAF0006880 PMID: 12773383|CGD_REF: CAL0087974 heterozygous diploid, classical genetics (haploinsufficient phenotype assay) null CAI-4 filamentous growth: decreased solid Spider medium heterozygous transposon insertion C. albicans FGR45 ORF FGR45 CAF0006881 PMID: 12773383|CGD_REF: CAL0087974 heterozygous diploid, classical genetics (haploinsufficient phenotype assay) unspecified CAI-4 filamentous growth: abnormal solid Spider medium or solid YEPD plus serum decreased or increased filamentous growth, depending on the allele; transposon insertion proximal to, but not within, the ORF C. albicans FGR49 ORF FGR49 CAF0006882 PMID: 12773383|CGD_REF: CAL0087974 heterozygous diploid, classical genetics (haploinsufficient phenotype assay) null CAI-4 viable heterozygous transposon insertion C. albicans FGR49 ORF FGR49 CAF0006882 PMID: 12773383|CGD_REF: CAL0087974 heterozygous diploid, classical genetics (haploinsufficient phenotype assay) null CAI-4 filamentous growth: increased solid YEPD plus serum heterozygous transposon insertion C. albicans LET1 ORF LET1 CAL0006585 PMID: 6757662|CGD_REF: CAL0081474 heterozygous diploid, classical genetics null Not recorded viable C. albicans LET1 ORF LET1 CAL0006585 PMID: 6757662|CGD_REF: CAL0081474 homozygous diploid, classical genetics null Not recorded inviable C. albicans LET2 ORF LET2 CAL0006586 PMID: 6757662|CGD_REF: CAL0081474 heterozygous diploid, classical genetics null Not recorded viable C. albicans LET2 ORF LET2 CAL0006586 PMID: 6757662|CGD_REF: CAL0081474 homozygous diploid, classical genetics null Not recorded inviable C. albicans MET ORF MET CAL0006602 PMID: 6757662|CGD_REF: CAL0081474 homozygous diploid, classical genetics null Not recorded auxotrophy methionine C. albicans TER1 ncRNA CAF0007465 PMID: 17609387|CGD_REF: CAL0118095 homozygous diploid, classical genetics null Not recorded telomere length: decreased C. albicans TER1 ncRNA CAF0007465 PMID: 17609387|CGD_REF: CAL0118095 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.10 ORF ALK8 CAL0000502 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, competitive growth (haploinsufficient phenotype assay, barcode deletion set) null SC5314 resistance to chemicals: increased tubercidin C. albicans orf19.10 ORF ALK8 CAL0000502 PMID: 11536334|CGD_REF: CAL0080928 homozygous diploid, classical genetics null Not recorded utilization of carbon source: decreased alkanes C. albicans orf19.10 ORF ALK8 CAL0000502 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.10 ORF ALK8 CAL0000502 PMID: 14507372|CGD_REF: CAL0088818 heterozygous diploid, large-scale survey (large-scale identification of essential genes by gene replacement and conditional expression (GRACE) method) repressible CAI-4 viable one allele is deleted and the other is placed under repressible Tet promoter C. albicans orf19.10 ORF ALK8 CAL0000502 PMID: 11536334|CGD_REF: CAL0080928 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.10 ORF ALK8 CAL0000502 PMID: 11536334|CGD_REF: CAL0080928 heterozygous diploid, classical genetics overexpression Not recorded resistance to chemicals: increased fluconazole C. albicans orf19.100 ORF CAL0002961 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.100 ORF CAL0002961 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.100 ORF CAL0002961 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.100 ORF CAL0002961 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient YPD medium C. albicans orf19.100 ORF CAL0002961 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.1002 ORF CAL0001015 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.1002 ORF CAL0001015 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.1002 ORF CAL0001015 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.1002 ORF CAL0001015 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.1005 ORF CAL0001021 PMID: 14663094|CGD_REF: CAL0080633 homozygous diploid, systematic mutation set (homozygous insertion mutants generated with URA3-ARG4-URA3 (UAU1) cassette) null BWP17 viable C. albicans orf19.1007 ORF KCS1 CAL0001024 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.1007 ORF KCS1 CAL0001024 PMID: 15964282|CGD_REF: CAL0114274 homozygous diploid, systematic mutation set (split-marker transposon insertion strategy to disrupt both alleles) null BWP17 viable C. albicans orf19.1007 ORF KCS1 CAL0001024 PMID: 15964282|CGD_REF: CAL0114274 homozygous diploid, systematic mutation set (split-marker transposon insertion strategy to disrupt both alleles) null BWP17 biofilm formation: normal C. albicans orf19.101 ORF RIM9 CAL0002962 PMID: 19230847|CGD_REF: CAL0122428 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased lithium chloride solid YPD medium C. albicans orf19.101 ORF RIM9 CAL0002962 PMID: 19230847|CGD_REF: CAL0122428 homozygous diploid, classical genetics null Not recorded alkaline pH resistance: decreased solid SC medium at pH 10.0 C. albicans orf19.101 ORF RIM9 CAL0002962 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: decreased growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.101 ORF RIM9 CAL0002962 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: abnormal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.101 ORF RIM9 CAL0002962 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, classical genetics null SN152 germ tube formation: decreased serum-containing medium C. albicans orf19.101 ORF RIM9 CAL0002962 PMID: 19230847|CGD_REF: CAL0122428 homozygous diploid, classical genetics null BWP17 filamentous growth: decreased M199 medium, pH 7.5 C. albicans orf19.101 ORF RIM9 CAL0002962 PMID: 22381911|CGD_REF: CAL0000144077 homozygous diploid, classical genetics null SN152 filamentous growth: decreased mutant was sensitive to pH 8.8 and showed marked growth reduction at higher pH (pH 9.7 and 10.0) C. albicans orf19.101 ORF RIM9 CAL0002962 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.101 ORF RIM9 CAL0002962 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.1010 ORF MNT3 CAL0001038 PMID: 20164191|CGD_REF: CAL0124956 homozygous diploid, classical genetics null mnt3::hisG/mnt3::hisG CAI-4 viable C. albicans orf19.1011 ORF MNN21 CAL0001040 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.1011 ORF MNN21 CAL0001040 PMID: 23633946|CGD_REF: CAL0000172007 homozygous diploid, classical genetics null mnn21::dpl200/mnn21::dpl200 CAI-4 chemical compound accumulation: decreased mannan C. albicans orf19.1011 ORF MNN21 CAL0001040 PMID: 23633946|CGD_REF: CAL0000172007 homozygous diploid, classical genetics null mnn21::dpl200/mnn21::dpl200 CAI-4 induction of host response: decreased Deletion of MNN21 resulted in a 50% reduction in TNF-alpha secretion from PBMCs C. albicans orf19.1012 ORF CAL0001042 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.1026 ORF CAL0001085 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.1026 ORF CAL0001085 PMID: 21135205|CGD_REF: CAL0139967 heterozygous diploid, large-scale survey (large-scale identification of genes essential for virulence in mouse) repressible CAI-4 virulence: absent mouse intravenous infection C. albicans orf19.1027 ORF PDR16 CAL0001086 PMID: 16796687|CGD_REF: CAL0116205 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.1027 ORF PDR16 CAL0001086 PMID: 16796687|CGD_REF: CAL0116205 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased fluconazole C. albicans orf19.1027 ORF PDR16 CAL0001086 PMID: 16796687|CGD_REF: CAL0116205 heterozygous diploid, classical genetics overexpression Not recorded resistance to chemicals: increased fluconazole C. albicans orf19.1029 ORF RPP1 CAL0001088 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.1031 ORF HMG1 CAL0001113 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.1031 ORF HMG1 CAL0001113 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, competitive growth (haploinsufficient phenotype assay, barcode deletion set) null SC5314 resistance to chemicals: decreased lovastatin C. albicans orf19.1031 ORF HMG1 CAL0001113 PMID: 21135205|CGD_REF: CAL0139967 heterozygous diploid, competitive growth (large-scale identification of genes essential for virulence in mouse) repressible CAI-4 virulence: decreased mouse intravenous infection C. albicans orf19.1032 ORF SKO1 CAL0001116 PMID: 20041210|CGD_REF: CAL0124764 homozygous diploid, systematic mutation set null SN152 resistance to chemicals: increased rapamycin strongly resistant C. albicans orf19.1032 ORF SKO1 CAL0001116 PMID: 20041210|CGD_REF: CAL0124764 homozygous diploid, systematic mutation set null SN152 metal resistance: decreased copper(2+) strongly sensitive C. albicans orf19.1032 ORF SKO1 CAL0001116 PMID: 20388546|CGD_REF: CAL0125367 homozygous diploid, classical genetics null sko1::hisG/sko1::hisG-URA3-hisG CAI-4 virulence: normal mouse intravenous infection C. albicans orf19.1032 ORF SKO1 CAL0001116 PMID: 20388546|CGD_REF: CAL0125367 homozygous diploid, classical genetics null sko1::hisG/sko1::hisG-URA3-hisG RM1000 virulence: normal mouse intravenous infection C. albicans orf19.1032 ORF SKO1 CAL0001116 PMID: 20388546|CGD_REF: CAL0125367 homozygous diploid, classical genetics null sko1::hisG/sko1::hisG-URA3-hisG RM1000 filamentous growth: increased medium with 5% serum at 30 deg mouse intravenous infection C. albicans orf19.1032 ORF SKO1 CAL0001116 PMID: 20388546|CGD_REF: CAL0125367 homozygous diploid, classical genetics null sko1::hisG/sko1::hisG-URA3-hisG CAF2-1 viable C. albicans orf19.1032 ORF SKO1 CAL0001116 PMID: 20388546|CGD_REF: CAL0125367 homozygous diploid, classical genetics null sko1::hisG/sko1::hisG-URA3-hisG CAI-4 viable C. albicans orf19.1032 ORF SKO1 CAL0001116 PMID: 20388546|CGD_REF: CAL0125367 homozygous diploid, classical genetics null sko1::hisG/sko1::hisG-URA3-hisG RM1000 viable C. albicans orf19.1032 ORF SKO1 CAL0001116 PMID: 18434592|CGD_REF: CAL0118971 homozygous diploid, classical genetics null BWP17 viable C. albicans orf19.1032 ORF SKO1 CAL0001116 PMID: 18434592|CGD_REF: CAL0118971 homozygous diploid, classical genetics null BWP17 resistance to chemicals: decreased caspofungin C. albicans orf19.1032 ORF SKO1 CAL0001116 PMID: 11532939|CGD_REF: CAL0081163 homozygous diploid, classical genetics null CAI-4 viable no obvious phenotype C. albicans orf19.1033 ORF STR2 CAL0001118 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.1033 ORF STR2 CAL0001118 PMID: 14663094|CGD_REF: CAL0080633 homozygous diploid, systematic mutation set (homozygous insertion mutants generated with URA3-ARG4-URA3 (UAU1) cassette) null BWP17 viable C. albicans orf19.1035 ORF WAR1 CAL0001122 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.1035 ORF WAR1 CAL0001122 PMID: 16544288|CGD_REF: CAL0115709 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.1035 ORF WAR1 CAL0001122 PMID: 16544288|CGD_REF: CAL0115709 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased weak organic acids C. albicans orf19.1035 ORF WAR1 CAL0001122 PMID: 16544288|CGD_REF: CAL0115709 heterozygous diploid, classical genetics overexpression Not recorded resistance to chemicals: increased sorbic acid C. albicans orf19.1035 ORF WAR1 CAL0001122 PMID: 22359502|CGD_REF: CAL0000144048 homozygous diploid, classical genetics null BWP17 viable insertion mutant, independent SN152 deletion mutant strain also tested C. albicans orf19.1035 ORF WAR1 CAL0001122 PMID: 22359502|CGD_REF: CAL0000144048 homozygous diploid, classical genetics null BWP17 adhesion: decreased insertion mutant, independent SN152 deletion mutant strain also tested C. albicans orf19.1036 ORF MNS1 CAL0001124 PMID: 17933909|CGD_REF: CAL0118852 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased Calcofluor White C. albicans orf19.1036 ORF MNS1 CAL0001124 PMID: 19154328|CGD_REF: CAL0122236 heterozygous diploid, classical genetics null Other C. albicans hyphal growth: abnormal semisolid substrate decreased hyphal tip oscillation C. albicans orf19.1036 ORF MNS1 CAL0001124 PMID: 19154328|CGD_REF: CAL0122236 homozygous diploid, classical genetics null Other C. albicans hyphal growth: absent 20% serum, solid media C. albicans orf19.1036 ORF MNS1 CAL0001124 PMID: 17933909|CGD_REF: CAL0118852 homozygous diploid, classical genetics null Not recorded vegetative growth: decreased rate rich medium at 30 deg C C. albicans orf19.1036 ORF MNS1 CAL0001124 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.1036 ORF MNS1 CAL0001124 PMID: 17933909|CGD_REF: CAL0118852 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.1036 ORF MNS1 CAL0001124 PMID: 17933909|CGD_REF: CAL0118852 homozygous diploid, classical genetics null CAI-4 filamentous growth: absent solid Spider medium C. albicans orf19.1036 ORF MNS1 CAL0001124 PMID: 17933909|CGD_REF: CAL0118852 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased Hygromycin B C. albicans orf19.1036 ORF MNS1 CAL0001124 PMID: 17933909|CGD_REF: CAL0118852 homozygous diploid, classical genetics null Not recorded chemical compound accumulation: decreased mannan decreased cell wall mannan C. albicans orf19.1036 ORF MNS1 CAL0001124 PMID: 17933909|CGD_REF: CAL0118852 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased Congo Red C. albicans orf19.1036 ORF MNS1 CAL0001124 PMID: 17933909|CGD_REF: CAL0118852 homozygous diploid, classical genetics null Not recorded chemical compound accumulation: decreased glucan decreased cell wall glucan C. albicans orf19.1036 ORF MNS1 CAL0001124 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.1036 ORF MNS1 CAL0001124 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.1036 ORF MNS1 CAL0001124 PMID: 20123707|CGD_REF: CAL0125018 homozygous diploid, classical genetics null CAI-4 resistance to phagocytosis: decreased mutants taken up more rapidly by bone-marrow derived macrophages in vitro model of infection (bone-marrow derived macrophages) C. albicans orf19.1036 ORF MNS1 CAL0001124 PMID: 17933909|CGD_REF: CAL0118852 homozygous diploid, classical genetics null Not recorded virulence: decreased mouse intravenous infection C. albicans orf19.1036 ORF MNS1 CAL0001124 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.1036 ORF MNS1 CAL0001124 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.1040 ORF MAD2 CAL0001147 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.1040 ORF MAD2 CAL0001147 PMID: 12100546|CGD_REF: CAL0081501 heterozygous diploid, classical genetics null Not recorded viable C. albicans orf19.1040 ORF MAD2 CAL0001147 PMID: 12100546|CGD_REF: CAL0081501 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.1040 ORF MAD2 CAL0001147 PMID: 12100546|CGD_REF: CAL0081501 homozygous diploid, classical genetics null Not recorded oxidative stress resistance: decreased hydrogen peroxide C. albicans orf19.1040 ORF MAD2 CAL0001147 PMID: 12100546|CGD_REF: CAL0081501 homozygous diploid, classical genetics null Not recorded chromosome segregation: abnormal increased mitotic chromosome loss C. albicans orf19.1040 ORF MAD2 CAL0001147 PMID: 12100546|CGD_REF: CAL0081501 homozygous diploid, classical genetics null CAI-4 filamentous growth: absent inside macrophages C. albicans orf19.1040 ORF MAD2 CAL0001147 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, competitive growth (haploinsufficient phenotype assay, barcode deletion set) null SC5314 resistance to chemicals: decreased nocodazole C. albicans orf19.1040 ORF MAD2 CAL0001147 PMID: 12100546|CGD_REF: CAL0081501 heterozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased nocodazole C. albicans orf19.1040 ORF MAD2 CAL0001147 PMID: 12100546|CGD_REF: CAL0081501 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased nocodazole C. albicans orf19.1040 ORF MAD2 CAL0001147 PMID: 12100546|CGD_REF: CAL0081501 homozygous diploid, classical genetics null CAI-4 resistance to killing by host cells: decreased decreased survival in the presence of macrophages in vitro model of infection (peritoneal macrophages from thiolglycolate elicited inflammation) C. albicans orf19.1040 ORF MAD2 CAL0001147 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: decreased growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.1040 ORF MAD2 CAL0001147 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.1040 ORF MAD2 CAL0001147 PMID: 12100546|CGD_REF: CAL0081501 homozygous diploid, classical genetics null Not recorded virulence: decreased exhibits decreased kidney colonization mouse intravenous infection C. albicans orf19.1040 ORF MAD2 CAL0001147 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: decreased rate liquid synthetic complete medium C. albicans orf19.1040 ORF MAD2 CAL0001147 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.1041 ORF CAL0001150 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.1041 ORF CAL0001150 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: abnormal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.1041 ORF CAL0001150 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: decreased rate liquid synthetic complete medium C. albicans orf19.1041 ORF CAL0001150 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.1042 ORF POR1 CAL0001151 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.1045 ORF CAL0001156 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, competitive growth (haploinsufficient phenotype assay, barcode deletion set) null SC5314 resistance to chemicals: decreased 5-fluorouracil C. albicans orf19.1045 ORF CAL0001156 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, competitive growth (haploinsufficient phenotype assay, barcode deletion set) null SC5314 resistance to chemicals: decreased tubercidin C. albicans orf19.1045 ORF CAL0001156 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, competitive growth (haploinsufficient phenotype assay, barcode deletion set) null SC5314 resistance to chemicals: decreased flucytosine C. albicans orf19.1045 ORF CAL0001156 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.1047 ORF ERB1 CAL0001157 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, competitive growth (haploinsufficient phenotype assay, barcode deletion set) null SC5314 resistance to chemicals: decreased 5-fluorouracil C. albicans orf19.1047 ORF ERB1 CAL0001157 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, competitive growth (haploinsufficient phenotype assay, barcode deletion set) null SC5314 resistance to chemicals: decreased tubercidin C. albicans orf19.1047 ORF ERB1 CAL0001157 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, competitive growth (haploinsufficient phenotype assay, barcode deletion set) null SC5314 resistance to chemicals: decreased flucytosine C. albicans orf19.1047 ORF ERB1 CAL0001157 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.1047 ORF ERB1 CAL0001157 PMID: 21135205|CGD_REF: CAL0139967 heterozygous diploid, competitive growth (large-scale identification of genes essential for virulence in mouse) repressible CAI-4 virulence: decreased mouse intravenous infection C. albicans orf19.1048 ORF IFD6 CAL0001158 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.1048 ORF IFD6 CAL0001158 PMID: 19529758|CGD_REF: CAL0123764 heterozygous diploid, classical genetics overexpression BWP17 biofilm formation: abnormal C. albicans orf19.1049 ORF CAL0001159 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.1049 ORF CAL0001159 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.1049 ORF CAL0001159 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.1049 ORF CAL0001159 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.105 ORF HAL22 CAL0002967 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.1051 ORF HTA2 CAL0001183 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.1054 ORF CAL0001188 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 invasive growth: decreased solid SLAD media C. albicans orf19.1055 ORF CDC3 CAL0001190 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.1055 ORF CDC3 CAL0001190 PMID: 12181342|CGD_REF: CAL0080842 homozygous diploid, classical genetics null Not recorded inviable homozygous null mutant strain could not be recovered, suggesting that the gene is essential under the selection conditions C. albicans orf19.1059 ORF HHF1 CAL0001194 PMID: 20498713|CGD_REF: CAL0125627 homozygous diploid, classical genetics null BWP17 viable C. albicans orf19.1062 ORF CAL0001205 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.1063 ORF CAL0001206 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.1064 ORF ACS2 CAL0001207 PMID: 18689527|CGD_REF: CAL0119372 heterozygous diploid, classical genetics repressible Not recorded utilization of carbon source: abnormal unable to grow on glucose, acetate, ethanol, lactate; grows on citrate, glycerol, oleate C. albicans orf19.1064 ORF ACS2 CAL0001207 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.1064 ORF ACS2 CAL0001207 PMID: 18689527|CGD_REF: CAL0119372 homozygous diploid, classical genetics null Not recorded inviable C. albicans orf19.1065 ORF SSA2 CAL0001208 PMID: 17999963|CGD_REF: CAL0118846 homozygous diploid, classical genetics null Not recorded toxin resistance: increased active fragment of human histatin 5 C. albicans orf19.1065 ORF SSA2 CAL0001208 PMID: 19006817|CGD_REF: CAL0121046 homozygous diploid, classical genetics null Not recorded toxin resistance: increased human salivary histatin 5 C. albicans orf19.1065 ORF SSA2 CAL0001208 PMID: 42021|CGD_REF: CAL0116480 homozygous diploid, classical genetics null Not recorded toxin resistance: increased human salivary histatin 5 C. albicans orf19.1065 ORF SSA2 CAL0001208 PMID: 16720580|CGD_REF: CAL0116423 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.1066 ORF GIG1 CAL0001209 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.1066 ORF GIG1 CAL0001209 PMID: 20675577|CGD_REF: CAL0126007 homozygous diploid, classical genetics null gig1::HIS1/gig1::ARG4 BWP17 viable C. albicans orf19.1066 ORF GIG1 CAL0001209 PMID: 20675577|CGD_REF: CAL0126007 homozygous diploid, classical genetics null gig1::HIS1/gig1::ARG4 BWP17 resistance to chemicals: increased nikkomycin Z C. albicans orf19.1067 ORF GPM2 CAL0001210 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.1069 ORF RPN4 CAL0001212 PMID: 20041210|CGD_REF: CAL0124764 homozygous diploid, systematic mutation set null SN152 resistance to chemicals: decreased fluconazole strongly sensitive C. albicans orf19.1069 ORF RPN4 CAL0001212 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.107 ORF CAL0002969 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.1070 ORF CAL0001220 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.1077 ORF ATM1 CAL0001228 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.1082.1 ORF CAF0006920 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 invasive growth: decreased solid SLAD media C. albicans orf19.1083 ORF CAL0001251 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.1084 ORF CDC39 CAL0001252 PMID: 20141603|CGD_REF: CAL0124951 homozygous diploid, systematic mutation set (homozygous insertion mutants generated with URA3-ARG4-URA3 (UAU1) cassette) null BWP17 hyphal growth: absent YPD plus 10% serum at 37 deg C C. albicans orf19.1084 ORF CDC39 CAL0001252 PMID: 20141603|CGD_REF: CAL0124951 homozygous diploid, systematic mutation set (homozygous insertion mutants generated with URA3-ARG4-URA3 (UAU1) cassette) null BWP17 colony appearance: abnormal 10% serum or Spider media at 37 deg C colonies are smooth C. albicans orf19.1084 ORF CDC39 CAL0001252 PMID: 12773383|CGD_REF: CAL0087974 heterozygous diploid, classical genetics (haploinsufficient phenotype assay) null CAI-4 filamentous growth: decreased solid YEPD plus serum heterozygous transposon insertion C. albicans orf19.1084 ORF CDC39 CAL0001252 PMID: 20141603|CGD_REF: CAL0124951 homozygous diploid, systematic mutation set (homozygous insertion mutants generated with URA3-ARG4-URA3 (UAU1) cassette) null BWP17 viable C. albicans orf19.1084 ORF CDC39 CAL0001252 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 invasive growth: decreased solid SLAD media C. albicans orf19.1085 ORF CAL0001253 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.109 ORF CAL0002971 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.1092 ORF CAL0001279 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: decreased growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.1092 ORF CAL0001279 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: abnormal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.1092 ORF CAL0001279 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, classical genetics null SN152 germ tube formation: decreased serum-containing medium C. albicans orf19.1092 ORF CAL0001279 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.1092 ORF CAL0001279 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.1093 ORF FLO8 CAL0001280 PMID: 16267276|CGD_REF: CAL0115298 homozygous diploid, classical genetics null CAI-4 hyphal growth: absent liquid or solid serum-containing media, solid Lee's medium deletion of entire gene or of LUFS domain C. albicans orf19.1093 ORF FLO8 CAL0001280 PMID: 16267276|CGD_REF: CAL0115298 heterozygous diploid, classical genetics null CAI-4 hyphal growth: decreased partial defect C. albicans orf19.1093 ORF FLO8 CAL0001280 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.1093 ORF FLO8 CAL0001280 PMID: 16267276|CGD_REF: CAL0115298 heterozygous diploid, classical genetics null Not recorded viable C. albicans orf19.1093 ORF FLO8 CAL0001280 PMID: 16267276|CGD_REF: CAL0115298 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.1093 ORF FLO8 CAL0001280 PMID: 16267276|CGD_REF: CAL0115298 homozygous diploid, classical genetics null CAI-4 filamentous growth: increased embedded in YPS agar, 25 deg C exhibits microaerophilic growth C. albicans orf19.1093 ORF FLO8 CAL0001280 PMID: 19666778|CGD_REF: CAL0123941 homozygous diploid, classical genetics null Not recorded virulence: decreased C. elegans infection C. albicans orf19.1093 ORF FLO8 CAL0001280 PMID: 16267276|CGD_REF: CAL0115298 homozygous diploid, classical genetics null Not recorded virulence: absent mouse intravenous infection C. albicans orf19.1093 ORF FLO8 CAL0001280 PMID: 20223293|CGD_REF: CAL0125139 homozygous diploid, classical genetics null BWP17 filamentous growth: absent within G. mellonella C. albicans orf19.1093 ORF FLO8 CAL0001280 PMID: 20223293|CGD_REF: CAL0125139 homozygous diploid, classical genetics null BWP17 filamentous growth: absent in 10% hemolymph and in the presence of G. mellonella hemocytes C. albicans orf19.1093 ORF FLO8 CAL0001280 PMID: 20223293|CGD_REF: CAL0125139 homozygous diploid, classical genetics null BWP17 virulence: decreased G. mellonella infection insect infection C. albicans orf19.1097 ORF ALS2 CAL0001283 PMID: 15870470|CGD_REF: CAL0082507 heterozygous diploid, classical genetics repressible CAI-4 germ tube formation: decreased liquid RPMI or Lee's media, or in reconstituted human epithelium C. albicans orf19.1097 ORF ALS2 CAL0001283 PMID: 15870470|CGD_REF: CAL0082507 heterozygous diploid, classical genetics overexpression Not recorded viable no apparent phenotype C. albicans orf19.1097 ORF ALS2 CAL0001283 PMID: 15870470|CGD_REF: CAL0082507 heterozygous diploid, classical genetics null Not recorded viable C. albicans orf19.1097 ORF ALS2 CAL0001283 PMID: 15870470|CGD_REF: CAL0082507 heterozygous diploid, classical genetics repressible Not recorded viable C. albicans orf19.1097 ORF ALS2 CAL0001283 PMID: 15870470|CGD_REF: CAL0082507 heterozygous diploid, classical genetics repressible Not recorded adhesion: decreased adhesion to vascular endothelial cells or reconstituted human epithelium, but not BEC C. albicans orf19.1097 ORF ALS2 CAL0001283 PMID: 15870470|CGD_REF: CAL0082507 homozygous diploid, classical genetics null Not recorded inviable homozygous null mutant strain could not be recovered, suggesting that the gene is essential under the selection conditions C. albicans orf19.1097 ORF ALS2 CAL0001283 PMID: 15870470|CGD_REF: CAL0082507 heterozygous diploid, classical genetics repressible CAI-4 biofilm formation: decreased biofilm formation on a catheter in vitro C. albicans orf19.1097 ORF ALS2 CAL0001283 PMID: 15870470|CGD_REF: CAL0082507 heterozygous diploid, classical genetics repressible Not recorded virulence: decreased ex vivo model of infection C. albicans orf19.1097 ORF ALS2 CAL0001283 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 invasive growth: decreased solid SLAD media C. albicans orf19.1105.2 ORF PGA56 CAL0006784 PMID: 16099828|CGD_REF: CAL0114565 homozygous diploid, classical genetics null Not recorded viable strain is Sou+ and monosomic for Chr. 5 C. albicans orf19.1105.3 ORF CAF0006917 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient YPD medium C. albicans orf19.1105.3 ORF CAF0006917 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient SC medium C. albicans orf19.1105.3 ORF CAF0006917 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient YNB medium C. albicans orf19.1108 ORF HAM1 CAL0001858 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.111 ORF CAN2 CAL0002992 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.1110 ORF CAL0001872 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.1111 ORF CAL0001873 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.1112 ORF BUD7 CAL0001875 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.1115 ORF GUK1 CAL0001880 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.1119 ORF MTR10 CAL0001884 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.1124 ORF CAL0001920 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.1124 ORF CAL0001920 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.1124 ORF CAL0001920 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.1124 ORF CAL0001920 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.1124 ORF CAL0001920 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.113 ORF CIP1 CAL0002993 PMID: 16339733|CGD_REF: CAL0115110 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.113 ORF CIP1 CAL0002993 PMID: 16339733|CGD_REF: CAL0115110 homozygous diploid, classical genetics null Not recorded oxidative stress resistance: decreased hydrogen peroxide C. albicans orf19.113 ORF CIP1 CAL0002993 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: abnormal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.113 ORF CIP1 CAL0002993 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.113 ORF CIP1 CAL0002993 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.113 ORF CIP1 CAL0002993 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.1135 ORF CAS1 CAL0001964 PMID: 15964282|CGD_REF: CAL0114274 homozygous diploid, systematic mutation set (split-marker transposon insertion strategy to disrupt both alleles) null BWP17 viable C. albicans orf19.1135 ORF CAS1 CAL0001964 PMID: 16552442|CGD_REF: CAL0115731 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.1135 ORF CAS1 CAL0001964 PMID: 19463063|CGD_REF: CAL0123630 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.1135 ORF CAS1 CAL0001964 PMID: 15964282|CGD_REF: CAL0114274 homozygous diploid, systematic mutation set (split-marker transposon insertion strategy to disrupt both alleles) null BWP17 biofilm formation: normal C. albicans orf19.1135 ORF CAS1 CAL0001964 PMID: 16552442|CGD_REF: CAL0115731 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased caspofungin effect is slight C. albicans orf19.1135 ORF CAS1 CAL0001964 PMID: 19463063|CGD_REF: CAL0123630 homozygous diploid, systematic mutation set (split-marker transposon insertion strategy to disrupt both alleles) null BWP17 virulence: normal Toll mutant D. melanogaster invasive infection insect infection C. albicans orf19.1136 ORF CAL0001966 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.1137 ORF CAL0001967 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.1139 ORF CAL0001968 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.1142 ORF AVT4 CAL0002003 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.1143 ORF CAL0002005 PMID: 21135205|CGD_REF: CAL0139967 heterozygous diploid, competitive growth (large-scale identification of genes essential for virulence in mouse) repressible CAI-4 virulence: normal mouse intravenous infection C. albicans orf19.1150 ORF CAL0002036 PMID: 22438810|CGD_REF: CAL0000156986 homozygous diploid, classical genetics null BWP17 viable C. albicans orf19.1150 ORF CAL0002036 PMID: 22438810|CGD_REF: CAL0000156986 homozygous diploid, classical genetics null BWP17 virulence: decreased mutants have reduced capacity to damage oral epithelial cells in vitro model of infection (monolayers of oral epithelial cells) C. albicans orf19.1152 ORF CAL0002042 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.1153 ORF GAD1 CAL0002044 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.1153 ORF GAD1 CAL0002044 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 invasive growth: decreased solid SLAD media C. albicans orf19.1154 ORF EGD1 CAL0002046 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.1155 ORF DPP2 CAL0002048 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.1156 ORF FUS1 CAL0002050 PMID: 20402797|CGD_REF: CAL0125391 homozygous diploid, classical genetics null Other C. albicans viable C. albicans orf19.1156 ORF FUS1 CAL0002050 PMID: 20870881|CGD_REF: CAL0126465 homozygous diploid, classical genetics null SC5314 mating efficiency: decreased C. albicans orf19.1159 ORF CAL0002052 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.1159 ORF CAL0002052 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 invasive growth: decreased solid SLAD media C. albicans orf19.1160 ORF CAL0002067 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.1161 ORF PLD1 CAL0002069 PMID: 12384374|CGD_REF: CAL0081697 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased propranolol C. albicans orf19.1161 ORF PLD1 CAL0002069 PMID: 11283284|CGD_REF: CAL0081687 homozygous diploid, classical genetics null Not recorded hyphal growth: increased solid cornmeal plus Tween 80 medium hyphal morphology is abnormal C. albicans orf19.1161 ORF PLD1 CAL0002069 PMID: 12384374|CGD_REF: CAL0081697 homozygous diploid, classical genetics null CAF2-1 hyphal growth: abnormal increased inhibition of hyphal growth by propranolol C. albicans orf19.1161 ORF PLD1 CAL0002069 PMID: 11283284|CGD_REF: CAL0081687 homozygous diploid, classical genetics null Not recorded hyphal growth: normal liquid media C. albicans orf19.1161 ORF PLD1 CAL0002069 PMID: 11283284|CGD_REF: CAL0081687 homozygous diploid, classical genetics null Not recorded hyphal growth: decreased solid serum-containing or Spider media C. albicans orf19.1161 ORF PLD1 CAL0002069 PMID: 11283284|CGD_REF: CAL0081687 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.1161 ORF PLD1 CAL0002069 PMID: 15552646|CGD_REF: CAL0082141 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.1161 ORF PLD1 CAL0002069 PMID: 11283284|CGD_REF: CAL0081687 homozygous diploid, classical genetics null Not recorded invasive growth: decreased C. albicans orf19.1161 ORF PLD1 CAL0002069 PMID: 11283284|CGD_REF: CAL0081687 homozygous diploid, classical genetics null Not recorded virulence: normal reconstituted human epithelium ex vivo model of infection C. albicans orf19.1161 ORF PLD1 CAL0002069 PMID: 15552646|CGD_REF: CAL0082141 homozygous diploid, classical genetics null Not recorded virulence: decreased decreased organ colonization, despite wild-type intestinal colonization mouse gastrointestinal tract infection C. albicans orf19.1161 ORF PLD1 CAL0002069 PMID: 11283284|CGD_REF: CAL0081687 homozygous diploid, classical genetics null Not recorded virulence: absent immunodeficient mice mouse gastrointestinal tract infection C. albicans orf19.1161 ORF PLD1 CAL0002069 PMID: 15552646|CGD_REF: CAL0082141 homozygous diploid, classical genetics null Not recorded virulence: decreased decreased organ colonization, despite wild-type intestinal colonization mouse intravenous infection C. albicans orf19.1162 ORF CAL0002070 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.1162 ORF CAL0002070 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.1162 ORF CAL0002070 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.1162 ORF CAL0002070 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.1164 ORF GAR1 CAL0002072 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, competitive growth (haploinsufficient phenotype assay, barcode deletion set) null SC5314 resistance to chemicals: decreased tubercidin C. albicans orf19.1164 ORF GAR1 CAL0002072 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.1166 ORF CTA3 CAL0002073 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.1166 ORF CTA3 CAL0002073 PMID: 17431925|CGD_REF: CAL0117929 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.1166 ORF CTA3 CAL0002073 PMID: 17431925|CGD_REF: CAL0117929 homozygous diploid, classical genetics null Not recorded cellular morphology: normal no defects in polarized growth detected C. albicans orf19.1167 ORF CAL0002074 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.1168 ORF ZCF3 CAL0002075 PMID: 20041210|CGD_REF: CAL0124764 homozygous diploid, systematic mutation set null SN152 resistance to chemicals: decreased flucytosine strongly sensitive C. albicans orf19.1168 ORF ZCF3 CAL0002075 PMID: 20041210|CGD_REF: CAL0124764 homozygous diploid, systematic mutation set null SN152 resistance to chemicals: decreased rapamycin strongly sensitive C. albicans orf19.1168 ORF ZCF3 CAL0002075 PMID: 20041210|CGD_REF: CAL0124764 homozygous diploid, systematic mutation set null SN152 colony appearance: abnormal Spider medium at 30 deg C increased colony wrinkling and reduced peripheral filamentation C. albicans orf19.1168 ORF ZCF3 CAL0002075 PMID: 22073120|CGD_REF: CAL0000143592 homozygous diploid, classical genetics null BWP17 viable C. albicans orf19.1168 ORF ZCF3 CAL0002075 PMID: 22073120|CGD_REF: CAL0000143592 homozygous diploid, classical genetics null BWP17 hyphal growth: increased C. albicans orf19.1168 ORF ZCF3 CAL0002075 PMID: 22581526|CGD_REF: CAL0000157314 homozygous diploid, systematic mutation set null BWP17 resistance to chemicals: decreased caspofungin C. albicans orf19.1168 ORF ZCF3 CAL0002075 PMID: 22581526|CGD_REF: CAL0000157314 homozygous diploid, systematic mutation set null BWP17 resistance to chemicals: increased fluconazole C. albicans orf19.1168 ORF ZCF3 CAL0002075 PMID: 22581526|CGD_REF: CAL0000157314 homozygous diploid, systematic mutation set null BWP17 resistance to chemicals: increased caspofungin C. albicans orf19.117 ORF CAL0002999 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.117 ORF CAL0002999 PMID: 21135205|CGD_REF: CAL0139967 heterozygous diploid, large-scale survey (large-scale identification of genes essential for virulence in mouse) repressible CAI-4 virulence: absent mouse intravenous infection C. albicans orf19.1170 ORF ARO7 CAL0002091 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.1170 ORF ARO7 CAL0002091 PMID: 21135205|CGD_REF: CAL0139967 heterozygous diploid, large-scale survey (large-scale identification of genes essential for virulence in mouse) repressible CAI-4 virulence: absent mouse intravenous infection C. albicans orf19.1171 ORF BTA1 CAL0002093 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.1171 ORF BTA1 CAL0002093 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.1171 ORF BTA1 CAL0002093 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: decreased rate liquid synthetic complete medium C. albicans orf19.1171 ORF BTA1 CAL0002093 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.1171 ORF BTA1 CAL0002093 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.1177 ORF CAL0002099 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient SLAD medium C. albicans orf19.1177 ORF CAL0002099 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 invasive growth: decreased solid SLAD media C. albicans orf19.1178 ORF CAL0002100 PMID: 15964282|CGD_REF: CAL0114274 homozygous diploid, systematic mutation set (split-marker transposon insertion strategy to disrupt both alleles) null BWP17 viable C. albicans orf19.1178 ORF CAL0002100 PMID: 15964282|CGD_REF: CAL0114274 homozygous diploid, systematic mutation set (split-marker transposon insertion strategy to disrupt both alleles) null BWP17 biofilm formation: normal C. albicans orf19.1179 ORF CAL0002101 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient SC medium C. albicans orf19.118 ORF FAD2 CAL0003001 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.118 ORF FAD2 CAL0003001 PMID: 16622072|CGD_REF: CAL0115920 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.118 ORF FAD2 CAL0003001 PMID: 16622072|CGD_REF: CAL0115920 homozygous diploid, classical genetics null Not recorded chemical compound accumulation: abnormal polyunsaturated fatty acid C. albicans orf19.118 ORF FAD2 CAL0003001 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: abnormal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.118 ORF FAD2 CAL0003001 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.118 ORF FAD2 CAL0003001 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.118 ORF FAD2 CAL0003001 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.1180 ORF CAL0002124 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.1180 ORF CAL0002124 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient YPD medium C. albicans orf19.1180 ORF CAL0002124 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient SC medium C. albicans orf19.1180 ORF CAL0002124 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient YNB medium C. albicans orf19.1180 ORF CAL0002124 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient SLAD medium C. albicans orf19.1185 ORF CAL0002130 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.1185 ORF CAL0002130 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.1185 ORF CAL0002130 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.1185 ORF CAL0002130 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.1185 ORF CAL0002130 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.1187 ORF CPH2 CAL0002132 PMID: 11533231|CGD_REF: CAL0080743 homozygous diploid, classical genetics null Not recorded hyphal growth: decreased defect is growth condition-specific C. albicans orf19.1187 ORF CPH2 CAL0002132 PMID: 11533231|CGD_REF: CAL0080743 homozygous diploid, classical genetics null Not recorded hyphal growth: decreased liquid Lee's medium with various carbon sources C. albicans orf19.1187 ORF CPH2 CAL0002132 PMID: 11533231|CGD_REF: CAL0080743 homozygous diploid, classical genetics null Not recorded hyphal growth: normal liquid serum-, GlcNAc-, or proline-containing media C. albicans orf19.1187 ORF CPH2 CAL0002132 PMID: 11533231|CGD_REF: CAL0080743 homozygous diploid, classical genetics null Not recorded hyphal growth: decreased solid SSA, Lee's, or serum-containing media C. albicans orf19.1187 ORF CPH2 CAL0002132 PMID: 11595734|CGD_REF: CAL0081060 homozygous diploid, classical genetics null Not recorded hyphal growth: decreased Lee's medium C. albicans orf19.1187 ORF CPH2 CAL0002132 PMID: 11595734|CGD_REF: CAL0081060 homozygous diploid, classical genetics null Not recorded hyphal growth: normal YPD plus serum medium at 37 deg C C. albicans orf19.1187 ORF CPH2 CAL0002132 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.1187 ORF CPH2 CAL0002132 PMID: 15964282|CGD_REF: CAL0114274 homozygous diploid, systematic mutation set (split-marker transposon insertion strategy to disrupt both alleles) null BWP17 viable C. albicans orf19.1187 ORF CPH2 CAL0002132 PMID: 11533231|CGD_REF: CAL0080743 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.1187 ORF CPH2 CAL0002132 PMID: 11533231|CGD_REF: CAL0080743 aneuploid, classical genetics overexpression Not recorded viable C. albicans orf19.1187 ORF CPH2 CAL0002132 PMID: 19463063|CGD_REF: CAL0123630 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.1187 ORF CPH2 CAL0002132 PMID: 15964282|CGD_REF: CAL0114274 homozygous diploid, systematic mutation set (split-marker transposon insertion strategy to disrupt both alleles) null BWP17 biofilm formation: normal C. albicans orf19.1187 ORF CPH2 CAL0002132 PMID: 11533231|CGD_REF: CAL0080743 heterozygous diploid, classical genetics overexpression Not recorded cell shape: abnormal cells are elongated C. albicans orf19.1187 ORF CPH2 CAL0002132 PMID: 20041210|CGD_REF: CAL0124764 homozygous diploid, systematic mutation set null SN152 colony appearance: abnormal Spider medium at 30 deg C reduced peripheral filamentation C. albicans orf19.1187 ORF CPH2 CAL0002132 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.1187 ORF CPH2 CAL0002132 PMID: 22365851|CGD_REF: CAL0000144076 homozygous diploid, classical genetics null SN95 filamentous growth: absent mutant did not filament in response to geldanamycin or elevated temperature (42 degrees C) C. albicans orf19.1187 ORF CPH2 CAL0002132 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: abnormal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.1187 ORF CPH2 CAL0002132 PMID: 19463063|CGD_REF: CAL0123630 homozygous diploid, systematic mutation set (split-marker transposon insertion strategy to disrupt both alleles) null BWP17 virulence: normal Toll mutant D. melanogaster invasive infection insect infection C. albicans orf19.1187 ORF CPH2 CAL0002132 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.1187 ORF CPH2 CAL0002132 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.119 ORF CAL0003003 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.1190 ORF STV1 CAL0002155 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.1190 ORF STV1 CAL0002155 PMID: 23316054|CGD_REF: CAL0000158474 homozygous diploid, classical genetics null BWP17 viable C. albicans orf19.1190 ORF STV1 CAL0002155 PMID: 23884420|CGD_REF: CAL0000172543 homozygous diploid, classical genetics null SN152 filamentous growth: decreased liquid Spider medium, with mannitol as carbon source reduction by 40% C. albicans orf19.1191 ORF CAL0002157 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.1192 ORF DNA2 CAL0002159 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.1193 ORF GNP1 CAL0002160 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.1195 ORF CAL0002161 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 invasive growth: decreased solid SLAD media C. albicans orf19.1196 ORF PKH3 CAL0002162 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.1198 ORF CAL0002163 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.1199 ORF NOP5 CAL0002164 PMID: 12773383|CGD_REF: CAL0087974 heterozygous diploid, classical genetics (haploinsufficient phenotype assay) null CAI-4 viable heterozygous transposon insertion C. albicans orf19.1199 ORF NOP5 CAL0002164 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.1201 ORF CAL0002761 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.1204 ORF CAL0002766 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.121 ORF ARC18 CAL0003027 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.121 ORF ARC18 CAL0003027 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, competitive growth (haploinsufficient phenotype assay, barcode deletion set) null SC5314 resistance to chemicals: decreased cytochalasin D C. albicans orf19.1210 ORF CAL0002787 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 invasive growth: decreased solid SLAD media C. albicans orf19.1214 ORF CAL0002793 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.1217 ORF CAL0002796 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.1219 ORF CAL0002798 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.1219 ORF CAL0002798 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.1219 ORF CAL0002798 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.1219 ORF CAL0002798 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.122 ORF CDC20 CAL0003029 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.122 ORF CDC20 CAL0003029 PMID: 21398510|CGD_REF: CAL0141801 heterozygous diploid, classical genetics repressible cdc20delta::URA3/MET3-CDC20 BWP17 viability: decreased repressing conditions, supplemented with methionine and cysteine C. albicans orf19.122 ORF CDC20 CAL0003029 PMID: 21398510|CGD_REF: CAL0141801 heterozygous diploid, classical genetics repressible cdc20delta::URA3/MET3-CDC20 BWP17 cell shape: abnormal repressing conditions, supplemented with methionine and cysteine highly elongated buds C. albicans orf19.122 ORF CDC20 CAL0003029 PMID: 21398510|CGD_REF: CAL0141801 heterozygous diploid, classical genetics repressible cdc20delta::URA3/MET3-CDC20 BWP17 cell cycle passage through the metaphase-anaphase transition: delayed repressing conditions, supplemented with methionine and cysteine C. albicans orf19.122 ORF CDC20 CAL0003029 PMID: 21398510|CGD_REF: CAL0141801 heterozygous diploid, classical genetics repressible cdc20delta::URA3/MET3-CDC20 BWP17 cell cycle progression in telophase: delayed repressing conditions, supplemented with methionine and cysteine C. albicans orf19.1220 ORF RVS167 CAL0002827 PMID: 19596778|CGD_REF: CAL0123901 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased lithium chloride C. albicans orf19.1220 ORF RVS167 CAL0002827 PMID: 19596778|CGD_REF: CAL0123901 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased Calcofluor White C. albicans orf19.1220 ORF RVS167 CAL0002827 PMID: 19596778|CGD_REF: CAL0123901 homozygous diploid, classical genetics null Not recorded toxin resistance: increased C. albicans orf19.1220 ORF RVS167 CAL0002827 PMID: 19596778|CGD_REF: CAL0123901 homozygous diploid, classical genetics null BWP17 hyphal growth: delayed serum-containing medium at 37 deg C C. albicans orf19.1220 ORF RVS167 CAL0002827 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.1220 ORF RVS167 CAL0002827 PMID: 14507372|CGD_REF: CAL0088818 heterozygous diploid, large-scale survey (large-scale identification of essential genes by gene replacement and conditional expression (GRACE) method) repressible CAI-4 viable one allele is deleted and the other is placed under repressible Tet promoter C. albicans orf19.1220 ORF RVS167 CAL0002827 PMID: 19596778|CGD_REF: CAL0123901 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.1220 ORF RVS167 CAL0002827 PMID: 19596778|CGD_REF: CAL0123901 homozygous diploid, classical genetics null Not recorded bud morphology: abnormal buds are larger and rounder than wild type C. albicans orf19.1220 ORF RVS167 CAL0002827 PMID: 19596778|CGD_REF: CAL0123901 homozygous diploid, classical genetics null Not recorded budding pattern: abnormal bud site selection is more random than in wild type C. albicans orf19.1220 ORF RVS167 CAL0002827 PMID: 19596778|CGD_REF: CAL0123901 homozygous diploid, classical genetics null Not recorded oxidative stress resistance: decreased hydrogen peroxide C. albicans orf19.1220 ORF RVS167 CAL0002827 PMID: 19596778|CGD_REF: CAL0123901 homozygous diploid, classical genetics null Not recorded endocytosis: decreased the endocytic marker FM4-64 is internalized to a lesser extent than in wild type C. albicans orf19.1220 ORF RVS167 CAL0002827 PMID: 19596778|CGD_REF: CAL0123901 homozygous diploid, classical genetics null BWP17 filamentous growth: abnormal solid medium with 4% serum C. albicans orf19.1220 ORF RVS167 CAL0002827 PMID: 19596778|CGD_REF: CAL0123901 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased Congo Red C. albicans orf19.1220 ORF RVS167 CAL0002827 PMID: 19596778|CGD_REF: CAL0123901 homozygous diploid, classical genetics null Not recorded resistance to chemicals: increased fluconazole C. albicans orf19.1220 ORF RVS167 CAL0002827 PMID: 19596778|CGD_REF: CAL0123901 homozygous diploid, classical genetics null Not recorded virulence: decreased exhibits decreased kidney colonization mouse intravenous infection C. albicans orf19.1220 ORF RVS167 CAL0002827 PMID: 20402797|CGD_REF: CAL0125391 homozygous diploid, classical genetics null Other C. albicans actin cytoskeleton morphology: abnormal increased numbers of cortical actin patches, polarized distrubution to hyphal tips is lost C. albicans orf19.1220 ORF RVS167 CAL0002827 PMID: 20402797|CGD_REF: CAL0125391 homozygous diploid, classical genetics null Other C. albicans viable C. albicans orf19.1220 ORF RVS167 CAL0002827 PMID: 20402797|CGD_REF: CAL0125391 homozygous diploid, classical genetics null Other C. albicans germ tube formation: abnormal YPD plus 10% serum, 37 degrees C mutant germ tubes are much shorter than wild-type germ tubes C. albicans orf19.1221 ORF ALG2 CAL0002829 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.1223 ORF DBF2 CAL0002833 PMID: 19460099|CGD_REF: CAL0123598 heterozygous diploid, classical genetics repressible Not recorded spindle morphology: abnormal defective mitotic spindle organization C. albicans orf19.1223 ORF DBF2 CAL0002833 PMID: 19460099|CGD_REF: CAL0123598 heterozygous diploid, classical genetics repressible BWP17 hyphal growth: decreased abnormal hyphal morphology C. albicans orf19.1223 ORF DBF2 CAL0002833 PMID: 19460099|CGD_REF: CAL0123598 heterozygous diploid, classical genetics repressible Not recorded cell cycle progression: arrested cell cycle arrest after DNA replication C. albicans orf19.1223 ORF DBF2 CAL0002833 PMID: 19460099|CGD_REF: CAL0123598 homozygous diploid, classical genetics null Not recorded inviable C. albicans orf19.1223 ORF DBF2 CAL0002833 PMID: 19460099|CGD_REF: CAL0123598 heterozygous diploid, classical genetics repressible Not recorded nuclear position: abnormal defective segregation and orientation of nuclei C. albicans orf19.1223 ORF DBF2 CAL0002833 PMID: 19460099|CGD_REF: CAL0123598 heterozygous diploid, classical genetics repressible Not recorded cytokinesis: abnormal unable to form septa during cytokinesis C. albicans orf19.1224 ORF FRP3 CAL0002835 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.1227 ORF ZCF4 CAL0002840 PMID: 15964282|CGD_REF: CAL0114274 homozygous diploid, systematic mutation set (split-marker transposon insertion strategy to disrupt both alleles) null BWP17 inviable homozygous null mutant strain could not be recovered, suggesting that the gene is essential under the selection conditions C. albicans orf19.1228 ORF HAP2 CAL0002841 PMID: 20041210|CGD_REF: CAL0124764 homozygous diploid, systematic mutation set null SN152 resistance to chemicals: decreased BPS (500 uM bathophenanthrolinedisulfonic?acid, an iron chelator) strongly sensitive C. albicans orf19.1228 ORF HAP2 CAL0002841 PMID: 20041210|CGD_REF: CAL0124764 homozygous diploid, systematic mutation set null SN152 vegetative growth: decreased SD or MM media at 30 deg C strongly decreased C. albicans orf19.1228 ORF HAP2 CAL0002841 PMID: 20041210|CGD_REF: CAL0124764 homozygous diploid, systematic mutation set null SN152 resistance to chemicals: increased rapamycin strongly resistant C. albicans orf19.1228 ORF HAP2 CAL0002841 PMID: 20041210|CGD_REF: CAL0124764 homozygous diploid, systematic mutation set null SN152 alkaline pH resistance: decreased pH 10.5 strongly sensitive C. albicans orf19.1228 ORF HAP2 CAL0002841 PMID: 20041210|CGD_REF: CAL0124764 homozygous diploid, systematic mutation set null SN152 metal resistance: increased copper(2+) strongly resistant C. albicans orf19.1228 ORF HAP2 CAL0002841 PMID: 21592964|CGD_REF: CAL0142015 homozygous diploid, classical genetics null SN152 RNA accumulation: decreased FRP1 mRNA C. albicans orf19.1228 ORF HAP2 CAL0002841 PMID: 21592964|CGD_REF: CAL0142015 homozygous diploid, classical genetics null SN152 RNA accumulation: decreased SIT1 mRNA C. albicans orf19.1228 ORF HAP2 CAL0002841 PMID: 21592964|CGD_REF: CAL0142015 homozygous diploid, classical genetics null SN152 RNA accumulation: decreased HMX1 mRNA C. albicans orf19.1228 ORF HAP2 CAL0002841 PMID: 21592964|CGD_REF: CAL0142015 homozygous diploid, classical genetics null SN152 RNA accumulation: increased ACO1 mRNA C. albicans orf19.1229 ORF CAL0002842 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.1229 ORF CAL0002842 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 invasive growth: decreased solid SLAD media C. albicans orf19.123 ORF RCN1 CAL0003031 PMID: 19755168|CGD_REF: CAL0124242 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased lithium chloride C. albicans orf19.123 ORF RCN1 CAL0003031 PMID: 19755168|CGD_REF: CAL0124242 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased sodium dodecyl sulfate C. albicans orf19.123 ORF RCN1 CAL0003031 PMID: 19755168|CGD_REF: CAL0124242 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.123 ORF RCN1 CAL0003031 PMID: 19755168|CGD_REF: CAL0124242 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased fluconazole C. albicans orf19.123 ORF RCN1 CAL0003031 PMID: 19755168|CGD_REF: CAL0124242 homozygous diploid, classical genetics null Not recorded virulence: normal mouse intravenous infection C. albicans orf19.123 ORF RCN1 CAL0003031 PMID: 19755168|CGD_REF: CAL0124242 homozygous diploid, classical genetics null Not recorded virulence: normal mouse oropharyngeal infection C. albicans orf19.1232 ORF VRG4 CAL0002875 PMID: 11741841|CGD_REF: CAL0081527 heterozygous diploid, classical genetics repressible Not recorded resistance to chemicals: normal Calcofluor White C. albicans orf19.1232 ORF VRG4 CAL0002875 PMID: 11741841|CGD_REF: CAL0081527 heterozygous diploid, classical genetics repressible Not recorded germ tube formation: absent liquid serum-containing medium pseudohyphal growth occurs C. albicans orf19.1232 ORF VRG4 CAL0002875 PMID: 11741841|CGD_REF: CAL0081527 heterozygous diploid, classical genetics repressible Not recorded germ tube formation: absent solid serum-containing or Spider media C. albicans orf19.1232 ORF VRG4 CAL0002875 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.1232 ORF VRG4 CAL0002875 PMID: 11741841|CGD_REF: CAL0081527 homozygous diploid, classical genetics null Not recorded inviable homozygous null mutant strain could not be recovered, suggesting that the gene is essential under the selection conditions C. albicans orf19.1232 ORF VRG4 CAL0002875 PMID: 11741841|CGD_REF: CAL0081527 heterozygous diploid, classical genetics repressible Not recorded chemical compound accumulation: decreased phosphomannan cell wall phosphomannan is decreased C. albicans orf19.1232 ORF VRG4 CAL0002875 PMID: 11741841|CGD_REF: CAL0081527 heterozygous diploid, classical genetics repressible Not recorded osmotic stress resistance: decreased cells lyse C. albicans orf19.1232 ORF VRG4 CAL0002875 PMID: 11741841|CGD_REF: CAL0081527 heterozygous diploid, classical genetics repressible Not recorded cytokinesis: decreased C. albicans orf19.1232 ORF VRG4 CAL0002875 PMID: 11741841|CGD_REF: CAL0081527 heterozygous diploid, classical genetics repressible Not recorded pseudohyphal growth: increased C. albicans orf19.1232 ORF VRG4 CAL0002875 PMID: 11741841|CGD_REF: CAL0081527 heterozygous diploid, classical genetics repressible Not recorded resistance to chemicals: decreased Hygromycin B C. albicans orf19.1232 ORF VRG4 CAL0002875 PMID: 11741841|CGD_REF: CAL0081527 heterozygous diploid, classical genetics repressible Not recorded resistance to chemicals: normal trisodium vanadate C. albicans orf19.1233 ORF ADE4 CAL0002876 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.1234 ORF FGR6-10 CAL0002878 PMID: 12773383|CGD_REF: CAL0087974 heterozygous diploid, classical genetics (haploinsufficient phenotype assay) unspecified CAI-4 filamentous growth: decreased solid Spider medium transposon insertion proximal to, but not within, the ORF C. albicans orf19.1235 ORF HOM3 CAL0002880 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.1236 ORF GVP36 CAL0002882 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.1237 ORF ARO9 CAL0002883 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.1238 ORF TUB4 CAL0002884 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient YPD medium C. albicans orf19.1239 ORF CAL0002885 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.1239 ORF CAL0002885 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.1239 ORF CAL0002885 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.1239 ORF CAL0002885 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 invasive growth: decreased solid SLAD media C. albicans orf19.1239 ORF CAL0002885 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.124 ORF CIC1 CAL0003033 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.1246 ORF CAL0002917 PMID: 20494978|CGD_REF: CAL0125636 heterozygous diploid, classical genetics null BWP17 resistance to chemicals: decreased clotrimazole (75 uM) growth in liquid culture confirmation of mutant phenotypes for heterozygous transposon insertion strains showing sensitivity in a large-scale assay C. albicans orf19.1248 ORF CAL0002919 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.1248 ORF CAL0002919 PMID: 19623926|CGD_REF: CAL0124054 heterozygous diploid, competitive growth (haploinsufficient phenotype assay, barcode deletion set) null SC5314 resistance to chemicals: increased parnafungin C. albicans orf19.1249 ORF CAL0002920 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.125 ORF EBP1 CAL0003035 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.125 ORF EBP1 CAL0003035 PMID: 14968428|CGD_REF: CAL0080690 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.1251 ORF BRN1 CAL0002947 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.1251 ORF BRN1 CAL0002947 PMID: 21135205|CGD_REF: CAL0139967 heterozygous diploid, large-scale survey (large-scale identification of genes essential for virulence in mouse) repressible CAI-4 virulence: absent mouse intravenous infection C. albicans orf19.1252 ORF YME1 CAL0002950 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.1252 ORF YME1 CAL0002950 PMID: 14663094|CGD_REF: CAL0080633 homozygous diploid, systematic mutation set (homozygous insertion mutants generated with URA3-ARG4-URA3 (UAU1) cassette) null BWP17 viable C. albicans orf19.1253 ORF PHO4 CAL0002952 PMID: 20041210|CGD_REF: CAL0124764 homozygous diploid, systematic mutation set null SN152 resistance to chemicals: decreased Phloxine B (6.03 uM) strongly sensitive C. albicans orf19.1253 ORF PHO4 CAL0002952 PMID: 20041210|CGD_REF: CAL0124764 homozygous diploid, systematic mutation set null SN152 utilization of phosphorus source: abnormal MM base medium lacking potassium phosphate severe growth defect, in contrast to the residual growth exhibited by most strains C. albicans orf19.1253 ORF PHO4 CAL0002952 PMID: 20041210|CGD_REF: CAL0124764 homozygous diploid, systematic mutation set null SN152 vegetative growth: decreased YEPD medium at 30 deg C, or blood agar at 37 deg C strongly decreased C. albicans orf19.1253 ORF PHO4 CAL0002952 PMID: 20041210|CGD_REF: CAL0124764 homozygous diploid, systematic mutation set null SN152 metal resistance: increased copper(2+) strongly resistant C. albicans orf19.1253 ORF PHO4 CAL0002952 PMID: 22253901|CGD_REF: CAL0000143881 homozygous diploid, classical genetics null BWP17 viable C. albicans orf19.1253 ORF PHO4 CAL0002952 PMID: 22253901|CGD_REF: CAL0000143881 homozygous diploid, classical genetics null SN152 filamentous growth: increased phosphate limitation C. albicans orf19.1253 ORF PHO4 CAL0002952 PMID: 22253901|CGD_REF: CAL0000143881 homozygous diploid, classical genetics null SN152 virulence: increased C. elegans infection C. albicans orf19.1254 ORF SEC23 CAL0002954 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.1255 ORF ZCF5 CAL0002955 PMID: 15964282|CGD_REF: CAL0114274 homozygous diploid, systematic mutation set (split-marker transposon insertion strategy to disrupt both alleles) null BWP17 viable C. albicans orf19.1255 ORF ZCF5 CAL0002955 PMID: 15964282|CGD_REF: CAL0114274 homozygous diploid, systematic mutation set (split-marker transposon insertion strategy to disrupt both alleles) null BWP17 biofilm formation: normal C. albicans orf19.1255 ORF ZCF5 CAL0002955 PMID: 22073120|CGD_REF: CAL0000143592 homozygous diploid, classical genetics null BWP17 viable C. albicans orf19.1255 ORF ZCF5 CAL0002955 PMID: 22073120|CGD_REF: CAL0000143592 homozygous diploid, classical genetics null BWP17 colony appearance: abnormal decreased colony wrinkling C. albicans orf19.1261 ORF CGT1 CAL0002984 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.1261 ORF CGT1 CAL0002984 PMID: 12477801|CGD_REF: CAL0080831 heterozygous diploid, classical genetics null Not recorded viable C. albicans orf19.1261 ORF CGT1 CAL0002984 PMID: 10708374|CGD_REF: CAL0080994 heterozygous diploid, classical genetics null cgt1::hisG-URA3-hisG CAI-4 heat sensitivity: decreased C. albicans orf19.1261 ORF CGT1 CAL0002984 PMID: 10708374|CGD_REF: CAL0080994 heterozygous diploid, classical genetics null cgt1::hisG-URA3-hisG CAI-4 resistance to chemicals: increased Hygromycin B C. albicans orf19.1261 ORF CGT1 CAL0002984 PMID: 10708374|CGD_REF: CAL0080994 heterozygous diploid, classical genetics null cgt1::hisG-URA3-hisG CAI-4 vegetative growth: decreased rate increased growth lag, but higher final culture density C. albicans orf19.1261 ORF CGT1 CAL0002984 PMID: 10708374|CGD_REF: CAL0080994 heterozygous diploid, classical genetics null cgt1::hisG-URA3-hisG CAI-4 virulence: normal wild-type kidney colonization guinea pig intravenous infection C. albicans orf19.1261 ORF CGT1 CAL0002984 PMID: 10708374|CGD_REF: CAL0080994 heterozygous diploid, classical genetics null cgt1::hisG-URA3-hisG CAI-4 virulence: increased wild-type kidney colonization mouse intravenous infection C. albicans orf19.1261 ORF CGT1 CAL0002984 PMID: 12477801|CGD_REF: CAL0080831 homozygous diploid, classical genetics null Not recorded inviable homozygous null mutant strain could not be recovered, suggesting that the gene is essential under the selection conditions C. albicans orf19.1263 ORF CFL1 CAL0002986 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.1263 ORF CFL1 CAL0002986 PMID: 24631590|CGD_REF: CAL0000173801 homozygous diploid, classical genetics null BWP17 viable C. albicans orf19.1263 ORF CFL1 CAL0002986 PMID: 24631590|CGD_REF: CAL0000173801 homozygous diploid, classical genetics null BWP17 chemical compound accumulation: increased iron(2+) C. albicans orf19.1263 ORF CFL1 CAL0002986 PMID: 24631590|CGD_REF: CAL0000173801 homozygous diploid, classical genetics null BWP17 virulence: decreased mouse intravenous infection C. albicans orf19.1263 ORF CFL1 CAL0002986 PMID: 24631590|CGD_REF: CAL0000173801 homozygous diploid, classical genetics null BWP17 oxidative stress resistance: decreased hydrogen peroxide (8 mM) C. albicans orf19.1263 ORF CFL1 CAL0002986 PMID: 24631590|CGD_REF: CAL0000173801 homozygous diploid, classical genetics null BWP17 oxidative stress resistance: decreased menadione (100 uM) C. albicans orf19.1263 ORF CFL1 CAL0002986 PMID: 24631590|CGD_REF: CAL0000173801 homozygous diploid, classical genetics null BWP17 filamentous growth: decreased C. albicans orf19.1264 ORF CFL2 CAL0002987 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.1264 ORF CFL2 CAL0002987 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: decreased growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.1264 ORF CFL2 CAL0002987 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.1264 ORF CFL2 CAL0002987 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.1264 ORF CFL2 CAL0002987 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.1267 ORF CAL0002990 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.1267 ORF CAL0002990 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.1267 ORF CAL0002990 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.1267 ORF CAL0002990 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.1267.1 ORF CAF0006921 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.1270 ORF FRE3 CAL0003015 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.1270 ORF FRE3 CAL0003015 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.1270 ORF FRE3 CAL0003015 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.1270 ORF FRE3 CAL0003015 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.1270 ORF FRE3 CAL0003015 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.1275 ORF GAT1 CAL0003020 PMID: 14617156|CGD_REF: CAL0081136 homozygous diploid, classical genetics null CAI-4 germ tube formation: delayed Lee's or M199 media slight delay C. albicans orf19.1275 ORF GAT1 CAL0003020 PMID: 14617156|CGD_REF: CAL0081136 homozygous diploid, classical genetics null CAI-4 hyphal growth: normal various liquid and solid media C. albicans orf19.1275 ORF GAT1 CAL0003020 PMID: 18547391|CGD_REF: CAL0119095 homozygous diploid, classical genetics null Not recorded utilization of nitrogen source: decreased bovine serum albumin as sole nitrogen source severe defect C. albicans orf19.1275 ORF GAT1 CAL0003020 PMID: 14617156|CGD_REF: CAL0081136 homozygous diploid, classical genetics null Not recorded vegetative growth: normal rate 100% serum C. albicans orf19.1275 ORF GAT1 CAL0003020 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.1275 ORF GAT1 CAL0003020 PMID: 14617156|CGD_REF: CAL0081136 heterozygous diploid, classical genetics null Not recorded viable C. albicans orf19.1275 ORF GAT1 CAL0003020 PMID: 14617156|CGD_REF: CAL0081136 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.1275 ORF GAT1 CAL0003020 PMID: 17369441|CGD_REF: CAL0117785 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.1275 ORF GAT1 CAL0003020 PMID: 17950010|CGD_REF: CAL0118825 homozygous diploid, classical genetics null Not recorded resistance to chemicals: increased rapamycin C. albicans orf19.1275 ORF GAT1 CAL0003020 PMID: 20041210|CGD_REF: CAL0124764 homozygous diploid, systematic mutation set null SN152 resistance to chemicals: increased rapamycin strongly resistant C. albicans orf19.1275 ORF GAT1 CAL0003020 PMID: 14617156|CGD_REF: CAL0081136 homozygous diploid, classical genetics null Not recorded chlamydospore formation: normal C. albicans orf19.1275 ORF GAT1 CAL0003020 PMID: 14617156|CGD_REF: CAL0081136 homozygous diploid, classical genetics null Not recorded utilization of nitrogen source: decreased tyrosine C. albicans orf19.1275 ORF GAT1 CAL0003020 PMID: 17950010|CGD_REF: CAL0118825 homozygous diploid, classical genetics null Not recorded utilization of nitrogen source: decreased tyrosine C. albicans orf19.1275 ORF GAT1 CAL0003020 PMID: 17950010|CGD_REF: CAL0118825 homozygous diploid, classical genetics null Not recorded utilization of nitrogen source: decreased isoleucine C. albicans orf19.1275 ORF GAT1 CAL0003020 PMID: 14617156|CGD_REF: CAL0081136 homozygous diploid, classical genetics null Not recorded utilization of nitrogen source: decreased isoleucine C. albicans orf19.1275 ORF GAT1 CAL0003020 PMID: 14617156|CGD_REF: CAL0081136 homozygous diploid, classical genetics null Not recorded utilization of nitrogen source: decreased tryptophan C. albicans orf19.1275 ORF GAT1 CAL0003020 PMID: 17950010|CGD_REF: CAL0118825 homozygous diploid, classical genetics null Not recorded utilization of nitrogen source: decreased tryptophan C. albicans orf19.1275 ORF GAT1 CAL0003020 PMID: 14617156|CGD_REF: CAL0081136 homozygous diploid, classical genetics null Not recorded virulence: absent mouse intravenous infection C. albicans orf19.1275 ORF GAT1 CAL0003020 PMID: 14617156|CGD_REF: CAL0081136 heterozygous diploid, classical genetics null Not recorded virulence: normal C. albicans orf19.1276 ORF CAL0003021 PMID: 14663094|CGD_REF: CAL0080633 homozygous diploid, systematic mutation set (homozygous insertion mutants generated with URA3-ARG4-URA3 (UAU1) cassette) null BWP17 viable C. albicans orf19.1276 ORF CAL0003021 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: decreased growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.1276 ORF CAL0003021 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.1276 ORF CAL0003021 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.1276 ORF CAL0003021 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.1276 ORF CAL0003021 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 invasive growth: decreased solid SLAD media C. albicans orf19.1277 ORF CAL0003022 PMID: 17873081|CGD_REF: CAL0118685 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.1277 ORF CAL0003022 PMID: 17873081|CGD_REF: CAL0118685 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased caspofungin C. albicans orf19.1279 ORF CDS1 CAL0003024 PMID: 12773383|CGD_REF: CAL0087974 heterozygous diploid, classical genetics (haploinsufficient phenotype assay) null CAI-4 viable heterozygous transposon insertion C. albicans orf19.1279 ORF CDS1 CAL0003024 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.1279 ORF CDS1 CAL0003024 PMID: 12773383|CGD_REF: CAL0087974 heterozygous diploid, classical genetics (haploinsufficient phenotype assay) null CAI-4 filamentous growth: decreased solid Spider medium heterozygous transposon insertion C. albicans orf19.1279 ORF CDS1 CAL0003024 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 invasive growth: decreased solid SLAD media C. albicans orf19.1280 ORF SUI1 CAL0003056 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.1282 ORF CKS1 CAL0003060 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.1283 ORF MEC1 CAL0003061 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.1283 ORF MEC1 CAL0003061 PMID: 21511048|CGD_REF: CAL0141918 homozygous diploid, classical genetics null mec1::CdHIS1/mec1::CdARG4 Other C. albicans viable C. albicans orf19.1283 ORF MEC1 CAL0003061 PMID: 21511048|CGD_REF: CAL0141918 homozygous diploid, classical genetics null mec1::CdHIS1/mec1::CdARG4 Other C. albicans resistance to chemicals: decreased ethylmethane sulfonate (0.03%) C. albicans orf19.1283 ORF MEC1 CAL0003061 PMID: 21511048|CGD_REF: CAL0141918 homozygous diploid, classical genetics null mec1::CdHIS1/mec1::CdARG4 Other C. albicans resistance to chemicals: decreased methyl methanesulfonate (0.01%) C. albicans orf19.1283 ORF MEC1 CAL0003061 PMID: 21511048|CGD_REF: CAL0141918 homozygous diploid, classical genetics null mec1::CdHIS1/mec1::CdARG4 Other C. albicans resistance to chemicals: decreased hydroxyurea (20 mM) C. albicans orf19.1283 ORF MEC1 CAL0003061 PMID: 21511048|CGD_REF: CAL0141918 homozygous diploid, classical genetics null mec1::CdHIS1/mec1::CdARG4 Other C. albicans chromosome/plasmid maintenance: decreased hydroxyurea (20 mM) increase in genome instability C. albicans orf19.1283 ORF MEC1 CAL0003061 PMID: 21511048|CGD_REF: CAL0141918 homozygous diploid, classical genetics null mec1::CdHIS1/mec1::CdARG4 Other C. albicans chromosome/plasmid maintenance: decreased increase in genome instability C. albicans orf19.1285 ORF CAL0003062 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.1286 ORF CAL0003063 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 invasive growth: decreased solid SLAD media C. albicans orf19.1287 ORF CAL0003064 PMID: 21414038|CGD_REF: CAL0141808 homozygous diploid, classical genetics null BWP17 viable C. albicans orf19.1288 ORF FOX2 CAL0003065 PMID: 19700635|CGD_REF: CAL0124154 homozygous diploid, classical genetics null Not recorded utilization of carbon source: absent extra-virgin olive oil C. albicans orf19.1288 ORF FOX2 CAL0003065 PMID: 16963628|CGD_REF: CAL0116907 homozygous diploid, classical genetics null Not recorded utilization of carbon source: decreased nonfermentable carbon sources severe decrease C. albicans orf19.1288 ORF FOX2 CAL0003065 PMID: 16963628|CGD_REF: CAL0116907 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.1288 ORF FOX2 CAL0003065 PMID: 18832312|CGD_REF: CAL0120314 homozygous diploid, classical genetics null Not recorded utilization of carbon source: decreased acetic acid C. albicans orf19.1288 ORF FOX2 CAL0003065 PMID: 17158734|CGD_REF: CAL0117267 homozygous diploid, classical genetics null Not recorded utilization of carbon source: absent palmitic acid C. albicans orf19.1288 ORF FOX2 CAL0003065 PMID: 16963628|CGD_REF: CAL0116907 homozygous diploid, classical genetics null Not recorded utilization of carbon source: decreased oleic acid C. albicans orf19.1288 ORF FOX2 CAL0003065 PMID: 17158734|CGD_REF: CAL0117267 homozygous diploid, classical genetics null Not recorded utilization of carbon source: absent oleic acid C. albicans orf19.1288 ORF FOX2 CAL0003065 PMID: 17158734|CGD_REF: CAL0117267 homozygous diploid, classical genetics null Not recorded utilization of carbon source: absent ethanol C. albicans orf19.1288 ORF FOX2 CAL0003065 PMID: 18832312|CGD_REF: CAL0120314 homozygous diploid, classical genetics null Not recorded utilization of carbon source: decreased ethanol C. albicans orf19.1288 ORF FOX2 CAL0003065 PMID: 17158734|CGD_REF: CAL0117267 homozygous diploid, classical genetics null Not recorded utilization of carbon source: absent linoleic acid C. albicans orf19.1288 ORF FOX2 CAL0003065 PMID: 17158734|CGD_REF: CAL0117267 homozygous diploid, classical genetics null Not recorded utilization of carbon source: decreased glycerol C. albicans orf19.1288 ORF FOX2 CAL0003065 PMID: 18832312|CGD_REF: CAL0120314 homozygous diploid, classical genetics null Not recorded peroxisomal morphology: abnormal peroxisomes are enlarged and abnormally shaped during growth on oleate, enlarged on ethanol C. albicans orf19.1288 ORF FOX2 CAL0003065 PMID: 17158734|CGD_REF: CAL0117267 homozygous diploid, classical genetics null Not recorded utilization of carbon source: absent myristic acid C. albicans orf19.1288 ORF FOX2 CAL0003065 PMID: 17158734|CGD_REF: CAL0117267 homozygous diploid, classical genetics null Not recorded utilization of carbon source: decreased citric acid C. albicans orf19.1288 ORF FOX2 CAL0003065 PMID: 17158734|CGD_REF: CAL0117267 homozygous diploid, classical genetics null Not recorded virulence: decreased slight decrease mouse intravenous infection C. albicans orf19.1288 ORF FOX2 CAL0003065 PMID: 19700635|CGD_REF: CAL0124154 homozygous diploid, classical genetics null Not recorded virulence: decreased slight decrease mouse intravenous infection C. albicans orf19.1288 ORF FOX2 CAL0003065 PMID: 16963628|CGD_REF: CAL0116907 homozygous diploid, classical genetics null Not recorded virulence: decreased BALB/c mice mouse intravenous infection C. albicans orf19.1291 ORF ABZ1 CAL0003102 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.1291 ORF ABZ1 CAL0003102 PMID: 14663094|CGD_REF: CAL0080633 homozygous diploid, systematic mutation set (homozygous insertion mutants generated with URA3-ARG4-URA3 (UAU1) cassette) null BWP17 viable C. albicans orf19.1295 ORF VAS1 CAL0003105 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.1299 ORF RPN6 CAL0003109 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.130 ORF VPS15 CAL0003067 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.130 ORF VPS15 CAL0003067 PMID: 24363364|CGD_REF: CAL0000173733 homozygous diploid, classical genetics null BWP17 viable C. albicans orf19.130 ORF VPS15 CAL0003067 PMID: 24363364|CGD_REF: CAL0000173733 homozygous diploid, classical genetics null BWP17 vacuolar morphology: abnormal enlarged vacuoles C. albicans orf19.130 ORF VPS15 CAL0003067 PMID: 24363364|CGD_REF: CAL0000173733 homozygous diploid, large-scale survey null BWP17 protein secretion: abnormal Kex2 secreted to the medium KEX2 C. albicans orf19.130 ORF VPS15 CAL0003067 PMID: 24363364|CGD_REF: CAL0000173733 homozygous diploid, large-scale survey null BWP17 resistance to chemicals: decreased Congo Red C. albicans orf19.130 ORF VPS15 CAL0003067 PMID: 24363364|CGD_REF: CAL0000173733 homozygous diploid, large-scale survey null BWP17 resistance to chemicals: decreased hydrogen peroxide C. albicans orf19.130 ORF VPS15 CAL0003067 PMID: 24363364|CGD_REF: CAL0000173733 homozygous diploid, large-scale survey null BWP17 resistance to chemicals: decreased sodium dodecyl sulfate C. albicans orf19.130 ORF VPS15 CAL0003067 PMID: 24363364|CGD_REF: CAL0000173733 homozygous diploid, large-scale survey null BWP17 metal resistance: decreased manganese(2+) C. albicans orf19.130 ORF VPS15 CAL0003067 PMID: 24363364|CGD_REF: CAL0000173733 homozygous diploid, large-scale survey null BWP17 metal resistance: decreased copper(2+) C. albicans orf19.130 ORF VPS15 CAL0003067 PMID: 24363364|CGD_REF: CAL0000173733 homozygous diploid, large-scale survey null BWP17 resistance to chemicals: decreased fluconazole C. albicans orf19.130 ORF VPS15 CAL0003067 PMID: 24363364|CGD_REF: CAL0000173733 homozygous diploid, large-scale survey null BWP17 resistance to chemicals: decreased protamine A C. albicans orf19.130 ORF VPS15 CAL0003067 PMID: 24363364|CGD_REF: CAL0000173733 homozygous diploid, large-scale survey null BWP17 virulence: decreased protamine A mouse oropharyngeal infection C. albicans orf19.130 ORF VPS15 CAL0003067 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient YNB medium C. albicans orf19.1300 ORF CAL0003697 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.1300 ORF CAL0003697 PMID: 20141603|CGD_REF: CAL0124951 homozygous diploid, systematic mutation set (homozygous insertion mutants generated with URA3-ARG4-URA3 (UAU1) cassette) null BWP17 colony appearance: abnormal 10% serum or Spider media at 37 deg C colonies are smoother than wild type but mutant is able to form true hyphae under liquid inducing conditions C. albicans orf19.1300 ORF CAL0003697 PMID: 20141603|CGD_REF: CAL0124951 homozygous diploid, systematic mutation set (homozygous insertion mutants generated with URA3-ARG4-URA3 (UAU1) cassette) null BWP17 viable C. albicans orf19.1304 ORF CAL0003704 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.1305 ORF CAL0003706 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.1306 ORF CAL0003707 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.1307 ORF CAL0003709 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.1308 ORF CAL0003710 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.1310 ORF CAL0003720 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.1311 ORF SPO75 CAL0003722 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.1313 ORF CDR3 CAL0003726 PMID: 9393682|CGD_REF: CAL0080894 aneuploid, classical genetics overexpression Not recorded resistance to chemicals: normal brefeldin A C. albicans orf19.1313 ORF CDR3 CAL0003726 PMID: 9393682|CGD_REF: CAL0080894 homozygous diploid, classical genetics null Not recorded viable wild-type growth rate C. albicans orf19.1313 ORF CDR3 CAL0003726 PMID: 11870854|CGD_REF: CAL0080933 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.1313 ORF CDR3 CAL0003726 PMID: 9393682|CGD_REF: CAL0080894 aneuploid, classical genetics overexpression Not recorded viable C. albicans orf19.1313 ORF CDR3 CAL0003726 PMID: 9393682|CGD_REF: CAL0080894 homozygous diploid, classical genetics null Not recorded cellular morphology: normal C. albicans orf19.1313 ORF CDR3 CAL0003726 PMID: 11870854|CGD_REF: CAL0080933 homozygous diploid, classical genetics null Not recorded chemical compound accumulation: abnormal phosphatidylethanolamine increased phosphatidylethanolamine content of plasma membrane C. albicans orf19.1313 ORF CDR3 CAL0003726 PMID: 9393682|CGD_REF: CAL0080894 aneuploid, classical genetics overexpression Not recorded resistance to chemicals: normal 4-nitroquinoline N-oxide C. albicans orf19.1313 ORF CDR3 CAL0003726 PMID: 9393682|CGD_REF: CAL0080894 aneuploid, classical genetics overexpression Not recorded resistance to chemicals: normal cycloheximide C. albicans orf19.1313 ORF CDR3 CAL0003726 PMID: 9393682|CGD_REF: CAL0080894 aneuploid, classical genetics overexpression Not recorded resistance to chemicals: normal cerulenin C. albicans orf19.1313 ORF CDR3 CAL0003726 PMID: 9756759|CGD_REF: CAL0080905 heterozygous diploid, classical genetics overexpression Not recorded resistance to chemicals: increased triazoles C. albicans orf19.1313 ORF CDR3 CAL0003726 PMID: 9393682|CGD_REF: CAL0080894 aneuploid, classical genetics overexpression Not recorded resistance to chemicals: normal 1,10-phenanthroline C. albicans orf19.1313 ORF CDR3 CAL0003726 PMID: 9393682|CGD_REF: CAL0080894 homozygous diploid, classical genetics null Not recorded resistance to chemicals: normal fluconazole C. albicans orf19.1313 ORF CDR3 CAL0003726 PMID: 9393682|CGD_REF: CAL0080894 aneuploid, classical genetics overexpression Not recorded resistance to chemicals: normal fluconazole C. albicans orf19.1314 ORF CAL0003728 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.1314 ORF CAL0003728 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.1314 ORF CAL0003728 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.1314 ORF CAL0003728 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.1317 ORF OSH3 CAL0003732 PMID: 17082746|CGD_REF: CAL0116918 heterozygous diploid, classical genetics null Not recorded viable C. albicans orf19.1317 ORF OSH3 CAL0003732 PMID: 17082746|CGD_REF: CAL0116918 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.1317 ORF OSH3 CAL0003732 PMID: 17082746|CGD_REF: CAL0116918 homozygous diploid, classical genetics null CAI-4 filamentous growth: decreased solid Spider medium C. albicans orf19.1317 ORF OSH3 CAL0003732 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.1317 ORF OSH3 CAL0003732 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.1317 ORF OSH3 CAL0003732 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.1317 ORF OSH3 CAL0003732 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient SC medium C. albicans orf19.1317 ORF OSH3 CAL0003732 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient YNB medium C. albicans orf19.1317 ORF OSH3 CAL0003732 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient SLAD medium C. albicans orf19.1317 ORF OSH3 CAL0003732 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.132 ORF CAL0003071 PMID: 20485517|CGD_REF: CAL0125674 homozygous diploid, classical genetics null SN152 filamentous growth: increased MTL a/alpha cells, YPD medium, elevated temperature wrinkled colonies composed of mostly true hyphae C. albicans orf19.1321 ORF HWP1 CAL0003753 PMID: 18765290|CGD_REF: CAL0119430 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased Calcofluor White C. albicans orf19.1321 ORF HWP1 CAL0003753 PMID: 10066176|CGD_REF: CAL0081427 homozygous diploid, classical genetics null Not recorded hyphal growth: normal M199 medium C. albicans orf19.1321 ORF HWP1 CAL0003753 PMID: 10464197|CGD_REF: CAL0081057 homozygous diploid, classical genetics null Not recorded hyphal growth: absent solid medium C. albicans orf19.1321 ORF HWP1 CAL0003753 PMID: 10464197|CGD_REF: CAL0081057 heterozygous diploid, classical genetics null Not recorded hyphal growth: decreased solid medium C. albicans orf19.1321 ORF HWP1 CAL0003753 PMID: 15042589|CGD_REF: CAL0080741 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.1321 ORF HWP1 CAL0003753 PMID: 19837954|CGD_REF: CAL0124430 homozygous diploid, classical genetics null SC5314 mating efficiency: decreased C. albicans orf19.1321 ORF HWP1 CAL0003753 PMID: 19837954|CGD_REF: CAL0124430 homozygous diploid, classical genetics null SC5314 biofilm formation: decreased C. albicans orf19.1321 ORF HWP1 CAL0003753 PMID: 10066176|CGD_REF: CAL0081427 homozygous diploid, classical genetics null Not recorded adhesion: decreased adhesion to human buccal epithelial cells C. albicans orf19.1321 ORF HWP1 CAL0003753 PMID: 15042589|CGD_REF: CAL0080741 homozygous diploid, classical genetics null Not recorded adhesion: normal adhesion to human FaDu oropharyngeal epithelial cells C. albicans orf19.1321 ORF HWP1 CAL0003753 PMID: 15262971|CGD_REF: CAL0082103 homozygous diploid, classical genetics null Not recorded adhesion: decreased adhesion to human buccal epithelial cells C. albicans orf19.1321 ORF HWP1 CAL0003753 PMID: 10722594|CGD_REF: CAL0081428 homozygous diploid, classical genetics null hwp1::hisG/hwp1::hisG-URA3-hisG CAI-4 virulence: decreased mouse intravenous infection C. albicans orf19.1321 ORF HWP1 CAL0003753 PMID: 10722594|CGD_REF: CAL0081428 heterozygous diploid, classical genetics null hwp1::hisG-URA3-hisG CAI-4 virulence: decreased mouse intravenous infection C. albicans orf19.1321 ORF HWP1 CAL0003753 PMID: 15817775|CGD_REF: CAL0104045 homozygous diploid, classical genetics null CAI-4 filamentous growth: normal filamentous growth defect observed in previous studies was shown to be due to URA3 effects, independent of HWP1 C. albicans orf19.1321 ORF HWP1 CAL0003753 PMID: 21407800|CGD_REF: CAL0141800 homozygous diploid, classical genetics null BWP17 interaction with host/environment: abnormal significantly reduced adhesion and damage to epithelial cells, but normal invasion ex vivo model of infection C. albicans orf19.1321 ORF HWP1 CAL0003753 PMID: 17030992|CGD_REF: CAL0116775 homozygous diploid, classical genetics null CAI-4 biofilm formation: decreased on a venous catheter in rat severe defect C. albicans orf19.1321 ORF HWP1 CAL0003753 PMID: 12011025|CGD_REF: CAL0081216 homozygous diploid, classical genetics null Not recorded virulence: decreased virulence may also be influenced by URA3 expression mouse intravenous infection C. albicans orf19.1321 ORF HWP1 CAL0003753 PMID: 10066176|CGD_REF: CAL0081427 homozygous diploid, classical genetics null Not recorded virulence: decreased mouse intravenous infection C. albicans orf19.1321 ORF HWP1 CAL0003753 PMID: 12011025|CGD_REF: CAL0081216 heterozygous diploid, classical genetics null Not recorded virulence: normal mouse intravenous infection C. albicans orf19.1321 ORF HWP1 CAL0003753 PMID: 15817775|CGD_REF: CAL0104045 homozygous diploid, classical genetics null Not recorded virulence: normal defect observed in previous studies was shown to be due to URA3 effects, independent of HWP1 C. albicans orf19.1321 ORF HWP1 CAL0003753 PMID: 22544909|CGD_REF: CAL0000157240 homozygous diploid, classical genetics null Other C. albicans virulence: decreased mutant has decreased oral fungal burden at day 1 and 5 post-infection other model (Immunosuppressed mice) C. albicans orf19.1321 ORF HWP1 CAL0003753 PMID: 16839200|CGD_REF: CAL0116292 homozygous diploid, classical genetics null Other C. albicans biofilm formation: abnormal Spider medium, 37 deg C for 60 h at 150-rpm agitation mutant has a partial biofilm defect as determined by biofilm biomass C. albicans orf19.1321 ORF HWP1 CAL0003753 PMID: 24260489|CGD_REF: CAL0000173704 homozygous diploid, classical genetics null SC5314 virulence: normal mouse intravenous infection C. albicans orf19.1321 ORF HWP1 CAL0003753 PMID: 24260489|CGD_REF: CAL0000173704 homozygous diploid, classical genetics null SC5314 biofilm formation: decreased C. albicans orf19.1321 ORF HWP1 CAL0003753 PMID: 24260489|CGD_REF: CAL0000173704 homozygous diploid, classical genetics null SC5314 virulence: decreased normal gut colonization, but decreased translocation into blood stream mouse gastrointestinal tract infection C. albicans orf19.1323 ORF CAL0003756 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.1324 ORF RAD2 CAL0003758 PMID: 18667577|CGD_REF: CAL0119361 homozygous diploid, classical genetics null Not recorded UV resistance: decreased C. albicans orf19.1324 ORF RAD2 CAL0003758 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.1324 ORF RAD2 CAL0003758 PMID: 18667577|CGD_REF: CAL0119361 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.1325 ORF ECM38 CAL0003759 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.1327 ORF RBT1 CAL0003763 PMID: 18765290|CGD_REF: CAL0119430 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased Calcofluor White C. albicans orf19.1327 ORF RBT1 CAL0003763 PMID: 14663094|CGD_REF: CAL0080633 homozygous diploid, systematic mutation set (homozygous insertion mutants generated with URA3-ARG4-URA3 (UAU1) cassette) null BWP17 viable C. albicans orf19.1327 ORF RBT1 CAL0003763 PMID: 10978273|CGD_REF: CAL0081429 homozygous diploid, classical genetics null CAI-4 viable no apparent growth defects under various laboratory conditions C. albicans orf19.1327 ORF RBT1 CAL0003763 PMID: 10978273|CGD_REF: CAL0081429 heterozygous diploid, classical genetics null CAI-4 viable C. albicans orf19.1327 ORF RBT1 CAL0003763 PMID: 19837954|CGD_REF: CAL0124430 homozygous diploid, classical genetics null SC5314 mating efficiency: decreased C. albicans orf19.1327 ORF RBT1 CAL0003763 PMID: 19837954|CGD_REF: CAL0124430 homozygous diploid, classical genetics null SC5314 biofilm formation: decreased C. albicans orf19.1327 ORF RBT1 CAL0003763 PMID: 10978273|CGD_REF: CAL0081429 heterozygous diploid, classical genetics null CAI-4 virulence: decreased mouse intravenous infection C. albicans orf19.1327 ORF RBT1 CAL0003763 PMID: 10978273|CGD_REF: CAL0081429 homozygous diploid, classical genetics null CAI-4 virulence: decreased mouse intravenous infection C. albicans orf19.1327 ORF RBT1 CAL0003763 PMID: 10978273|CGD_REF: CAL0081429 homozygous diploid, classical genetics null CAI-4 virulence: decreased rabbit corneal infection C. albicans orf19.1330 ORF CAL0003784 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 invasive growth: decreased solid SLAD media C. albicans orf19.1331 ORF HSM3 CAL0003786 PMID: 14663094|CGD_REF: CAL0080633 homozygous diploid, systematic mutation set (homozygous insertion mutants generated with URA3-ARG4-URA3 (UAU1) cassette) null BWP17 viable C. albicans orf19.1331 ORF HSM3 CAL0003786 PMID: 23856128|CGD_REF: CAL0000172540 homozygous diploid, classical genetics null BWP17 resistance to chemicals: decreased propolis C. albicans orf19.1331 ORF HSM3 CAL0003786 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient SLAD medium C. albicans orf19.1332 ORF SNG4 CAL0003788 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.1333 ORF SNG3 CAL0003790 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.1333 ORF SNG3 CAL0003790 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, competitive growth (haploinsufficient phenotype assay, barcode deletion set) null SC5314 resistance to chemicals: decreased ergosterol analogs (ECC69 and/or ECC1384) C. albicans orf19.1335 ORF CAL0003794 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.134 ORF CAL0003075 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 invasive growth: decreased solid SLAD media C. albicans orf19.1341 ORF PRR2 CAL0003821 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, competitive growth (haploinsufficient phenotype assay, barcode deletion set) null SC5314 resistance to chemicals: increased flucytosine C. albicans orf19.1341 ORF PRR2 CAL0003821 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.1341 ORF PRR2 CAL0003821 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.1341 ORF PRR2 CAL0003821 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.1341 ORF PRR2 CAL0003821 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.1341 ORF PRR2 CAL0003821 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.1342 ORF SHM1 CAL0003822 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.1343 ORF MED16 CAL0003824 PMID: 23873866|CGD_REF: CAL0000172574 homozygous diploid, classical genetics null SN152 phenotypic switching: abnormal C. albicans orf19.1345 ORF LIP8 CAL0003827 PMID: 17646357|CGD_REF: CAL0118481 homozygous diploid, classical genetics null Not recorded flocculation: increased C. albicans orf19.1345 ORF LIP8 CAL0003827 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.1345 ORF LIP8 CAL0003827 PMID: 17646357|CGD_REF: CAL0118481 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.1345 ORF LIP8 CAL0003827 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.1345 ORF LIP8 CAL0003827 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.1345 ORF LIP8 CAL0003827 PMID: 17646357|CGD_REF: CAL0118481 homozygous diploid, classical genetics null Not recorded virulence: decreased mouse intravenous infection C. albicans orf19.1345 ORF LIP8 CAL0003827 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.1345 ORF LIP8 CAL0003827 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.135 ORF EXO84 CAL0003078 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.135 ORF EXO84 CAL0003078 PMID: 24501427|CGD_REF: CAL0000173770 heterozygous diploid, classical genetics repressible exo84/pMAL2-EXO84 BWP17 inviable repressing conditions (on glucose) C. albicans orf19.135 ORF EXO84 CAL0003078 PMID: 24501427|CGD_REF: CAL0000173770 heterozygous diploid, classical genetics repressible exo84/pMAL2-EXO84 BWP17 cellular morphology: abnormal repressing conditions (shift from maltose to glucose) round, enlarged cells with wide necks and with some cells containing multiple nuclei C. albicans orf19.135 ORF EXO84 CAL0003078 PMID: 24501427|CGD_REF: CAL0000173770 heterozygous diploid, classical genetics repressible exo84::ARG4/Exo84-S256A S384A (nonphosphorylatable) BWP17 pseudohyphal growth: increased C. albicans orf19.1352 ORF TIM22 CAL0003855 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.1353 ORF CAL0003856 PMID: 22438810|CGD_REF: CAL0000156986 homozygous diploid, classical genetics null BWP17 viable C. albicans orf19.1353 ORF CAL0003856 PMID: 22438810|CGD_REF: CAL0000156986 homozygous diploid, classical genetics null BWP17 virulence: decreased mutants have reduced capacity to damage oral epithelial cells in vitro model of infection (monolayers of oral epithelial cells) C. albicans orf19.1355 ORF CAL0003859 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.1357 ORF FCY21 CAL0003863 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, competitive growth (haploinsufficient phenotype assay, barcode deletion set) null SC5314 resistance to chemicals: increased 5-fluorouracil C. albicans orf19.1357 ORF FCY21 CAL0003863 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, competitive growth (haploinsufficient phenotype assay, barcode deletion set) null SC5314 resistance to chemicals: increased flucytosine C. albicans orf19.1357 ORF FCY21 CAL0003863 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, competitive growth (haploinsufficient phenotype assay, barcode deletion set) null SC5314 resistance to chemicals: increased flucytosine C. albicans orf19.1357 ORF FCY21 CAL0003863 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.1358 ORF GCN4 CAL0003864 PMID: 12374745|CGD_REF: CAL0080781 homozygous diploid, classical genetics null CAI-4 germ tube formation: normal serum-containing medium C. albicans orf19.1358 ORF GCN4 CAL0003864 PMID: 15701793|CGD_REF: CAL0082332 homozygous diploid, classical genetics null CAI-4 germ tube formation: decreased liquid Lee's medium C. albicans orf19.1358 ORF GCN4 CAL0003864 PMID: 15075282|CGD_REF: CAL0081075 homozygous diploid, classical genetics null Not recorded hyphal growth: normal in biofilms C. albicans orf19.1358 ORF GCN4 CAL0003864 PMID: 15075282|CGD_REF: CAL0081075 homozygous diploid, classical genetics null Not recorded vegetative growth: decreased rate C. albicans orf19.1358 ORF GCN4 CAL0003864 PMID: 15964282|CGD_REF: CAL0114274 homozygous diploid, systematic mutation set (split-marker transposon insertion strategy to disrupt both alleles) null BWP17 viable C. albicans orf19.1358 ORF GCN4 CAL0003864 PMID: 12374745|CGD_REF: CAL0080781 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.1358 ORF GCN4 CAL0003864 PMID: 15964282|CGD_REF: CAL0114274 homozygous diploid, systematic mutation set (split-marker transposon insertion strategy to disrupt both alleles) null BWP17 biofilm formation: normal C. albicans orf19.1358 ORF GCN4 CAL0003864 PMID: 12374745|CGD_REF: CAL0080781 heterozygous diploid, classical genetics overexpression CAI-4 filamentous growth: abnormal filamentous growth is constitutive C. albicans orf19.1358 ORF GCN4 CAL0003864 PMID: 12374745|CGD_REF: CAL0080781 homozygous diploid, classical genetics null CAI-4 filamentous growth: abnormal filamentous growth is not induced by amino acid starvation C. albicans orf19.1358 ORF GCN4 CAL0003864 PMID: 15701793|CGD_REF: CAL0082332 homozygous diploid, classical genetics null CAI-4 filamentous growth: absent solid Lee's medium C. albicans orf19.1358 ORF GCN4 CAL0003864 PMID: 12374745|CGD_REF: CAL0080781 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased 3-aminotriazole C. albicans orf19.1358 ORF GCN4 CAL0003864 PMID: 15701793|CGD_REF: CAL0082332 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased 3-aminotriazole C. albicans orf19.1358 ORF GCN4 CAL0003864 PMID: 12374745|CGD_REF: CAL0080781 heterozygous diploid, classical genetics overexpression Not recorded resistance to chemicals: increased amitrole C. albicans orf19.1358 ORF GCN4 CAL0003864 PMID: 22406769|CGD_REF: CAL0000156984 homozygous diploid, classical genetics null gcn4::hisG/gcn4::HisG-URA3-HisG CAI-4 colony size: decreased C. albicans orf19.1358 ORF GCN4 CAL0003864 PMID: 22406769|CGD_REF: CAL0000156984 homozygous diploid, classical genetics null gcn4::hisG/gcn4::HisG-URA3-HisG CAI-4 viable C. albicans orf19.1358 ORF GCN4 CAL0003864 PMID: 22406769|CGD_REF: CAL0000156984 homozygous diploid, classical genetics null gcn4::hisG/gcn4::HisG-URA3-HisG CAI-4 filamentous growth: decreased mutant is not filamentous on GlcNAc C. albicans orf19.1358 ORF GCN4 CAL0003864 PMID: 22406769|CGD_REF: CAL0000156984 homozygous diploid, classical genetics null gcn4::hisG/gcn4::HisG-URA3-HisG CAI-4 colony shape: abnormal forms smooth colonies on GlcNAc medium instead of filamentous colonies as does wild-type C. albicans orf19.1358 ORF GCN4 CAL0003864 PMID: 15075282|CGD_REF: CAL0081075 homozygous diploid, classical genetics null CAI-4 biofilm formation: decreased C. albicans orf19.1358 ORF GCN4 CAL0003864 PMID: 15302823|CGD_REF: CAL0082106 heterozygous diploid, classical genetics null Not recorded virulence: normal mouse intravenous infection C. albicans orf19.1358 ORF GCN4 CAL0003864 PMID: 15302823|CGD_REF: CAL0082106 homozygous diploid, classical genetics null Not recorded virulence: normal mouse intravenous infection C. albicans orf19.136 ORF QDR3 CAL0003080 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.136 ORF QDR3 CAL0003080 PMID: 24621232|CGD_REF: CAL0000173797 homozygous diploid, classical genetics null SC5314 biofilm formation: abnormal altered biofilm architecture and thickness C. albicans orf19.136 ORF QDR3 CAL0003080 PMID: 24621232|CGD_REF: CAL0000173797 homozygous diploid, classical genetics null SC5314 virulence: decreased mouse intravenous infection C. albicans orf19.1361 ORF TIM23 CAL0003881 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.1361 ORF TIM23 CAL0003881 PMID: 21135205|CGD_REF: CAL0139967 heterozygous diploid, large-scale survey (large-scale identification of genes essential for virulence in mouse) repressible CAI-4 virulence: absent mouse intravenous infection C. albicans orf19.1362 ORF SMM1 CAL0003882 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.1362 ORF SMM1 CAL0003882 PMID: 23572557|CGD_REF: CAL0000158900 homozygous diploid, classical genetics null BWP17 resistance to chemicals: decreased fluconazole RPMI+MOPS+Histidine medium , 6 hours without shaking at 37 degrees C 24 hr fluconazole treatment in 96 well plates C. albicans orf19.1363 ORF CAL0003883 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.1364 ORF CAL0003884 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.1364 ORF CAL0003884 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.1364 ORF CAL0003884 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.1364 ORF CAL0003884 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.1365 ORF CAL0003885 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.1365 ORF CAL0003885 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, competitive growth (haploinsufficient phenotype assay, barcode deletion set) null SC5314 resistance to chemicals: decreased ergosterol analogs (ECC69 and/or ECC1384) C. albicans orf19.1365 ORF CAL0003885 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.1365 ORF CAL0003885 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.1365 ORF CAL0003885 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.1365 ORF CAL0003885 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.1366 ORF CAL0003886 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.1367 ORF MTW1 CAL0003887 PMID: 21276093|CGD_REF: CAL0141431 heterozygous diploid, classical genetics repressible mtw1::PCK1pr-MTW1(URA3)/mtw1::HIS1 (glucose-repressible PCK1 promoter) BWP17 inviable repressing conditions C. albicans orf19.1367 ORF MTW1 CAL0003887 PMID: 21276093|CGD_REF: CAL0141431 heterozygous diploid, classical genetics repressible mtw1::PCK1pr-MTW1(URA3)/mtw1::HIS1 (glucose-repressible PCK1 promoter) BWP17 cell cycle progression through the G2/M phase transition: arrested repressing conditions C. albicans orf19.1369 ORF CAL0003889 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.137 ORF CAL0003081 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.137 ORF CAL0003081 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.137 ORF CAL0003081 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.137 ORF CAL0003081 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.137 ORF CAL0003081 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.1370 ORF CAL0003906 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient YPD medium C. albicans orf19.1370 ORF CAL0003906 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient SLAD medium C. albicans orf19.1370 ORF CAL0003906 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 invasive growth: decreased solid SLAD media C. albicans orf19.1372 ORF CAL0003908 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 invasive growth: decreased solid SLAD media C. albicans orf19.1373 ORF INP51 CAL0003909 PMID: 18957583|CGD_REF: CAL0120459 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased Calcofluor White C. albicans orf19.1373 ORF INP51 CAL0003909 PMID: 18957583|CGD_REF: CAL0120459 homozygous diploid, classical genetics null Not recorded resistance to enzymatic treatment: decreased zymolyase C. albicans orf19.1373 ORF INP51 CAL0003909 PMID: 18957583|CGD_REF: CAL0120459 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased sodium dodecyl sulfate C. albicans orf19.1373 ORF INP51 CAL0003909 PMID: 18957583|CGD_REF: CAL0120459 homozygous diploid, classical genetics null CAI-4 hyphal growth: decreased on solid agar or embedded within agar C. albicans orf19.1373 ORF INP51 CAL0003909 PMID: 18957583|CGD_REF: CAL0120459 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.1373 ORF INP51 CAL0003909 PMID: 18957583|CGD_REF: CAL0120459 homozygous diploid, classical genetics null Not recorded chemical compound accumulation: abnormal phosphoinositide C. albicans orf19.1373 ORF INP51 CAL0003909 PMID: 18957583|CGD_REF: CAL0120459 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased caspofungin C. albicans orf19.1373 ORF INP51 CAL0003909 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: decreased growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.1373 ORF INP51 CAL0003909 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: abnormal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.1373 ORF INP51 CAL0003909 PMID: 18957583|CGD_REF: CAL0120459 homozygous diploid, classical genetics null Not recorded virulence: decreased mouse intravenous infection C. albicans orf19.1373 ORF INP51 CAL0003909 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.1373 ORF INP51 CAL0003909 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.1375 ORF LEU42 CAL0003911 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.1378 ORF SUP35 CAL0003914 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.138 ORF FIG1 CAL0003084 PMID: 17275302|CGD_REF: CAL0117325 homozygous diploid, classical genetics null CAI-4 hyphal growth: abnormal abnormal directional growth of hyphae C. albicans orf19.138 ORF FIG1 CAL0003084 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.138 ORF FIG1 CAL0003084 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.138 ORF FIG1 CAL0003084 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.138 ORF FIG1 CAL0003084 PMID: 20870881|CGD_REF: CAL0126465 homozygous diploid, classical genetics null SC5314 mating efficiency: decreased C. albicans orf19.138 ORF FIG1 CAL0003084 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.138 ORF FIG1 CAL0003084 PMID: 21216943|CGD_REF: CAL0141174 homozygous diploid, classical genetics null fig1::dpl200/fig1::dpl200 CAI-4 chemical compound accumulation: decreased calcium(2+) mating conditions (mixed population of opaque mating-competent cells or upon alpha pheromone stimulation) C. albicans orf19.1381 ORF CAL0003939 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.1382 ORF YEA4 CAL0003940 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.1382 ORF YEA4 CAL0003940 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.1382 ORF YEA4 CAL0003940 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.1382 ORF YEA4 CAL0003940 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.1382 ORF YEA4 CAL0003940 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.1386 ORF CAL0003943 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.1387 ORF CAL0003944 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.1388 ORF CAL0003945 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.1389 ORF CAL0003946 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.1390 ORF PMI1 CAL0003967 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.1390 ORF PMI1 CAL0003967 PMID: 7785330|CGD_REF: CAL0081735 heterozygous diploid, classical genetics null Not recorded viable C. albicans orf19.1390 ORF PMI1 CAL0003967 PMID: 7785330|CGD_REF: CAL0081735 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.1390 ORF PMI1 CAL0003967 PMID: 7785330|CGD_REF: CAL0081735 homozygous diploid, classical genetics null Not recorded cellular morphology: abnormal in the absence of exogenous D-mannose cells exhibit abnormal, swollen morphology and defect in cell separation C. albicans orf19.1390 ORF PMI1 CAL0003967 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 invasive growth: decreased solid SLAD media C. albicans orf19.1392 ORF CAL0003969 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: increased growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.1392 ORF CAL0003969 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.1392 ORF CAL0003969 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.1392 ORF CAL0003969 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.1394 ORF CAL0003971 PMID: 14663094|CGD_REF: CAL0080633 homozygous diploid, systematic mutation set (homozygous insertion mutants generated with URA3-ARG4-URA3 (UAU1) cassette) null BWP17 viable C. albicans orf19.1395 ORF CAL0003972 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.1397 ORF CAL0003974 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.1397 ORF CAL0003974 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: abnormal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.1397 ORF CAL0003974 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.1397 ORF CAL0003974 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.1400 ORF CAL0004448 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.1401 ORF EAP1 CAL0004450 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.1401 ORF EAP1 CAL0004450 PMID: 17416898|CGD_REF: CAL0117927 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.1401 ORF EAP1 CAL0004450 PMID: 17416898|CGD_REF: CAL0117927 homozygous diploid, classical genetics null Not recorded adhesion: decreased adhesion to polystyrene and to HEK293 kidney epithelial cell monolayers C. albicans orf19.1401 ORF EAP1 CAL0004450 PMID: 17416898|CGD_REF: CAL0117927 homozygous diploid, classical genetics null BWP17 biofilm formation: decreased both in vitro and in vivo assays C. albicans orf19.1401 ORF EAP1 CAL0004450 PMID: 19798425|CGD_REF: CAL0124304 homozygous diploid, classical genetics null Other C. albicans biofilm formation: abnormal C. albicans orf19.1401 ORF EAP1 CAL0004450 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.1401 ORF EAP1 CAL0004450 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.1401 ORF EAP1 CAL0004450 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth null SN152 competitive fitness: normal growth in BALB/c mouse host mouse intravenous infection C. albicans orf19.1401 ORF EAP1 CAL0004450 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.1402 ORF CCT2 CAL0004452 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.1403 ORF CAL0004453 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient YPD medium C. albicans orf19.1409 ORF VAC7 CAL0004468 PMID: 19040629|CGD_REF: CAL0121263 heterozygous diploid, classical genetics repressible CAI-4 hyphal growth: abnormal altered branching frequency in hyphae C. albicans orf19.1409 ORF VAC7 CAL0004468 PMID: 19040629|CGD_REF: CAL0121263 heterozygous diploid, classical genetics repressible Not recorded vacuolar morphology: abnormal decreased vacuole content C. albicans orf19.1409 ORF VAC7 CAL0004468 PMID: 19040629|CGD_REF: CAL0121263 heterozygous diploid, classical genetics repressible Not recorded vacuolar morphology: abnormal enlarged vacuoles, depleted in emerging buds in yeast-like cells C. albicans orf19.1409 ORF VAC7 CAL0004468 PMID: 14663094|CGD_REF: CAL0080633 homozygous diploid, systematic mutation set (homozygous insertion mutants generated with URA3-ARG4-URA3 (UAU1) cassette) null BWP17 viable C. albicans orf19.1409 ORF VAC7 CAL0004468 PMID: 19040629|CGD_REF: CAL0121263 heterozygous diploid, classical genetics repressible CAI-4 filamentous growth: abnormal agar-slide cultures with serum forms pseudohyphae instead of true hyphae C. albicans orf19.1411 ORF CAL0004478 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.1411 ORF CAL0004478 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.1411 ORF CAL0004478 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.1411 ORF CAL0004478 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.1411 ORF CAL0004478 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.1413 ORF YFH1 CAL0004482 PMID: 15469520|CGD_REF: CAL0090409 homozygous diploid, classical genetics null Not recorded vegetative growth: decreased rate both rich and minimal media C. albicans orf19.1413 ORF YFH1 CAL0004482 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.1413 ORF YFH1 CAL0004482 PMID: 15469520|CGD_REF: CAL0090409 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.1413 ORF YFH1 CAL0004482 PMID: 15469520|CGD_REF: CAL0090409 homozygous diploid, classical genetics null Not recorded oxidative stress resistance: decreased hydrogen peroxide C. albicans orf19.1413 ORF YFH1 CAL0004482 PMID: 15469520|CGD_REF: CAL0090409 homozygous diploid, classical genetics null Not recorded chemical compound excretion: abnormal flavin elevated secretion of flavins results in deep yellow culture supernatant C. albicans orf19.1413 ORF YFH1 CAL0004482 PMID: 15469520|CGD_REF: CAL0090409 homozygous diploid, classical genetics null Not recorded mitochondrial morphology: abnormal C. albicans orf19.1413 ORF YFH1 CAL0004482 PMID: 15469520|CGD_REF: CAL0090409 homozygous diploid, classical genetics null Not recorded small molecule transport: increased iron elevated iron uptake C. albicans orf19.1413 ORF YFH1 CAL0004482 PMID: 15469520|CGD_REF: CAL0090409 homozygous diploid, classical genetics null Not recorded chemical compound accumulation: increased reactive oxygen species C. albicans orf19.1413 ORF YFH1 CAL0004482 PMID: 15469520|CGD_REF: CAL0090409 homozygous diploid, classical genetics null Not recorded oxidative stress resistance: decreased paraquat C. albicans orf19.1415 ORF FRE10 CAL0004487 PMID: 16113264|CGD_REF: CAL0114585 homozygous diploid, classical genetics null Not recorded utilization of iron source: decreased decreased iron uptake from transferrin or ferric chloride iron source; decreased growth rate using holotransferrin iron source at pH 4.3-4.4, but no significant defect using holotransferrin, ferric ammonium sulfate, or ferrichrome at pH 6.3-6.4 C. albicans orf19.1415 ORF FRE10 CAL0004487 PMID: 10978273|CGD_REF: CAL0081429 homozygous diploid, classical genetics null CAI-4 viable no apparent growth defects under various laboratory conditions C. albicans orf19.1415 ORF FRE10 CAL0004487 PMID: 21414038|CGD_REF: CAL0141808 homozygous diploid, classical genetics null BWP17 viable C. albicans orf19.1415 ORF FRE10 CAL0004487 PMID: 21414038|CGD_REF: CAL0141808 homozygous diploid, classical genetics null BWP17 biofilm formation: normal C. albicans orf19.1415 ORF FRE10 CAL0004487 PMID: 10978273|CGD_REF: CAL0081429 homozygous diploid, classical genetics null CAI-4 virulence: normal rabbit corneal infection C. albicans orf19.1420 ORF CAL0004514 PMID: 20494978|CGD_REF: CAL0125636 heterozygous diploid, classical genetics null BWP17 resistance to chemicals: decreased clotrimazole (75 uM) growth in liquid culture confirmation of mutant phenotypes for heterozygous transposon insertion strains showing sensitivity in a large-scale assay C. albicans orf19.1421 ORF CAL0004516 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.1422 ORF FZO1 CAL0004518 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.1422 ORF FZO1 CAL0004518 PMID: 23979757|CGD_REF: CAL0000172675 homozygous diploid, classical genetics null SC5314 viable C. albicans orf19.1422 ORF FZO1 CAL0004518 PMID: 23979757|CGD_REF: CAL0000172675 homozygous diploid, classical genetics null SC5314 vegetative growth: decreased rate C. albicans orf19.1422 ORF FZO1 CAL0004518 PMID: 23979757|CGD_REF: CAL0000172675 homozygous diploid, classical genetics null SC5314 mitochondrial genome maintenance: abnormal nonfermentable carbon sources 94% of cells lack mtDNA C. albicans orf19.1422 ORF FZO1 CAL0004518 PMID: 23979757|CGD_REF: CAL0000172675 homozygous diploid, classical genetics null SC5314 respiratory growth: absent nonfermentable carbon sources 94% of cells lack mtDNA C. albicans orf19.1422 ORF FZO1 CAL0004518 PMID: 23979757|CGD_REF: CAL0000172675 homozygous diploid, classical genetics null SC5314 resistance to chemicals: decreased fluconazole C. albicans orf19.1422 ORF FZO1 CAL0004518 PMID: 23979757|CGD_REF: CAL0000172675 homozygous diploid, classical genetics null SC5314 resistance to chemicals: decreased itraconazole C. albicans orf19.1422 ORF FZO1 CAL0004518 PMID: 23979757|CGD_REF: CAL0000172675 homozygous diploid, classical genetics null SC5314 resistance to chemicals: decreased ketoconazole C. albicans orf19.1422 ORF FZO1 CAL0004518 PMID: 23979757|CGD_REF: CAL0000172675 homozygous diploid, classical genetics null SC5314 resistance to chemicals: decreased amphotericin B C. albicans orf19.1422 ORF FZO1 CAL0004518 PMID: 23979757|CGD_REF: CAL0000172675 homozygous diploid, classical genetics null SC5314 resistance to chemicals: decreased amphotericin B C. albicans orf19.1427 ORF CAL0004528 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.1428 ORF DUO1 CAL0004529 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient YNB medium C. albicans orf19.1428 ORF DUO1 CAL0004529 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient SLAD medium C. albicans orf19.1429 ORF SOH1 CAL0004531 PMID: 22496666|CGD_REF: CAL0000157144 homozygous diploid, classical genetics null BWP17 viable C. albicans orf19.1429 ORF SOH1 CAL0004531 PMID: 22496666|CGD_REF: CAL0000157144 homozygous diploid, classical genetics null BWP17 cytokinesis: abnormal C. albicans orf19.1429 ORF SOH1 CAL0004531 PMID: 22496666|CGD_REF: CAL0000157144 homozygous diploid, classical genetics null BWP17 resistance to chemicals: decreased formamide C. albicans orf19.1429 ORF SOH1 CAL0004531 PMID: 22496666|CGD_REF: CAL0000157144 homozygous diploid, classical genetics null BWP17 resistance to chemicals: decreased sodium dodecyl sulfate C. albicans orf19.1429 ORF SOH1 CAL0004531 PMID: 22496666|CGD_REF: CAL0000157144 homozygous diploid, classical genetics null BWP17 resistance to chemicals: decreased nystatin C. albicans orf19.1429 ORF SOH1 CAL0004531 PMID: 22496666|CGD_REF: CAL0000157144 homozygous diploid, classical genetics null BWP17 resistance to chemicals: decreased dimethyl sulfoxide C. albicans orf19.1429 ORF SOH1 CAL0004531 PMID: 22496666|CGD_REF: CAL0000157144 homozygous diploid, classical genetics null BWP17 cold sensitivity: increased 16 deg C. albicans orf19.1429 ORF SOH1 CAL0004531 PMID: 22496666|CGD_REF: CAL0000157144 homozygous diploid, classical genetics null BWP17 resistance to chemicals: decreased Congo Red C. albicans orf19.1429 ORF SOH1 CAL0004531 PMID: 22496666|CGD_REF: CAL0000157144 homozygous diploid, classical genetics null BWP17 resistance to chemicals: increased Calcofluor White C. albicans orf19.1429 ORF SOH1 CAL0004531 PMID: 22496666|CGD_REF: CAL0000157144 homozygous diploid, classical genetics null BWP17 filamentous growth: decreased C. albicans orf19.1429 ORF SOH1 CAL0004531 PMID: 22496666|CGD_REF: CAL0000157144 homozygous diploid, classical genetics null BWP17 virulence: decreased C. elegans infection C. albicans orf19.1429 ORF SOH1 CAL0004531 PMID: 22496666|CGD_REF: CAL0000157144 homozygous diploid, classical genetics null BWP17 biofilm formation: decreased C. albicans orf19.1429 ORF SOH1 CAL0004531 PMID: 22496666|CGD_REF: CAL0000157144 homozygous diploid, classical genetics null BWP17 resistance to chemicals: decreased hydrogen peroxide C. albicans orf19.1429 ORF SOH1 CAL0004531 PMID: 22496666|CGD_REF: CAL0000157144 homozygous diploid, classical genetics null BWP17 resistance to chemicals: decreased ethanol C. albicans orf19.1434 ORF CAL0004555 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.1434 ORF CAL0004555 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient YPD medium C. albicans orf19.144 ORF SNU114 CAL0003115 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.144 ORF SNU114 CAL0003115 PMID: 12524333|CGD_REF: CAL0080691 homozygous diploid, systematic mutation set (homozygous insertion mutants generated with URA3-ARG4-URA3 (UAU1) cassette) null BWP17 inviable homozygous null mutant strain could not be recovered, suggesting that the gene is essential under the selection conditions C. albicans orf19.1440 ORF CAL0004584 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient SC medium C. albicans orf19.1440 ORF CAL0004584 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 invasive growth: decreased solid SLAD media C. albicans orf19.1442 ORF PLB4.5 CAL0004588 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.1445 ORF ESC4 CAL0004594 PMID: 12773383|CGD_REF: CAL0087974 heterozygous diploid, classical genetics (haploinsufficient phenotype assay) null CAI-4 viable heterozygous deletion or transposon insertion C. albicans orf19.1445 ORF ESC4 CAL0004594 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.1445 ORF ESC4 CAL0004594 PMID: 12773383|CGD_REF: CAL0087974 heterozygous diploid, classical genetics (haploinsufficient phenotype assay) null CAI-4 filamentous growth: increased solid Spider medium heterozygous deletion or transposon insertion C. albicans orf19.1445 ORF ESC4 CAL0004594 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: decreased growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.1445 ORF ESC4 CAL0004594 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.1445 ORF ESC4 CAL0004594 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.1445 ORF ESC4 CAL0004594 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.1446 ORF CLB2 CAL0004596 PMID: 15888543|CGD_REF: CAL0114307 heterozygous diploid, classical genetics overexpression Not recorded germ tube formation: decreased serum-containing medium germ tubes are also shorter than wild-type C. albicans orf19.1446 ORF CLB2 CAL0004596 PMID: 15888543|CGD_REF: CAL0114307 heterozygous diploid, classical genetics repressible Not recorded germ tube formation: normal serum-containing medium C. albicans orf19.1446 ORF CLB2 CAL0004596 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.1446 ORF CLB2 CAL0004596 PMID: 15888543|CGD_REF: CAL0114307 heterozygous diploid, classical genetics null Not recorded viable C. albicans orf19.1446 ORF CLB2 CAL0004596 PMID: 15888543|CGD_REF: CAL0114307 heterozygous diploid, classical genetics repressible Not recorded inviable cell-cycle arrest in late anaphase/telophase as elongated filamentous, dinucleate cells with polarized cortical actin patches, indicating a mitotic exit defect C. albicans orf19.1446 ORF CLB2 CAL0004596 PMID: 15888543|CGD_REF: CAL0114307 homozygous diploid, classical genetics null Not recorded inviable homozygous null mutant strain could not be recovered, suggesting that the gene is essential under the selection conditions C. albicans orf19.1446 ORF CLB2 CAL0004596 PMID: 15888543|CGD_REF: CAL0114307 heterozygous diploid, classical genetics dominant negative Not recorded inviable mutant lacking the destruction box shows dominant inviability; terminal phenotype shows branching, elongated buds (increased polarized growth without cytokinesis) C. albicans orf19.1446 ORF CLB2 CAL0004596 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, competitive growth (haploinsufficient phenotype assay, barcode deletion set) null SC5314 resistance to chemicals: decreased amphotericin B C. albicans orf19.1447 ORF CAL0004598 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 invasive growth: decreased solid SLAD media C. albicans orf19.1448 ORF APT1 CAL0004599 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.1449 ORF CAL0004600 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.1449 ORF CAL0004600 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: abnormal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.1449 ORF CAL0004600 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.1449 ORF CAL0004600 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.1449 ORF CAL0004600 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 invasive growth: decreased solid SLAD media C. albicans orf19.1449 ORF CAL0004600 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.145 ORF RPB4 CAL0003117 PMID: 12773383|CGD_REF: CAL0087974 heterozygous diploid, classical genetics (haploinsufficient phenotype assay) null CAI-4 viable heterozygous transposon insertion C. albicans orf19.1451 ORF SRB9 CAL0004613 PMID: 12773383|CGD_REF: CAL0087974 heterozygous diploid, classical genetics (haploinsufficient phenotype assay) unspecified CAI-4 filamentous growth: decreased solid Spider medium transposon insertion proximal to, but not within, the ORF C. albicans orf19.1451 ORF SRB9 CAL0004613 PMID: 22496666|CGD_REF: CAL0000157144 homozygous diploid, classical genetics null BWP17 viable C. albicans orf19.1451 ORF SRB9 CAL0004613 PMID: 22496666|CGD_REF: CAL0000157144 homozygous diploid, classical genetics null BWP17 biofilm formation: decreased C. albicans orf19.1451 ORF SRB9 CAL0004613 PMID: 22496666|CGD_REF: CAL0000157144 homozygous diploid, classical genetics null BWP17 resistance to chemicals: decreased Congo Red C. albicans orf19.1451 ORF SRB9 CAL0004613 PMID: 22496666|CGD_REF: CAL0000157144 homozygous diploid, classical genetics null BWP17 resistance to chemicals: decreased Calcofluor White C. albicans orf19.1451 ORF SRB9 CAL0004613 PMID: 22496666|CGD_REF: CAL0000157144 homozygous diploid, classical genetics null BWP17 resistance to chemicals: decreased sodium dodecyl sulfate C. albicans orf19.1451 ORF SRB9 CAL0004613 PMID: 22496666|CGD_REF: CAL0000157144 homozygous diploid, classical genetics null BWP17 resistance to chemicals: decreased hydrogen peroxide C. albicans orf19.1451 ORF SRB9 CAL0004613 PMID: 22496666|CGD_REF: CAL0000157144 homozygous diploid, classical genetics null BWP17 resistance to chemicals: decreased ethanol C. albicans orf19.1453 ORF SPT5 CAL0004616 PMID: 12773383|CGD_REF: CAL0087974 heterozygous diploid, classical genetics (haploinsufficient phenotype assay) null CAI-4 viable heterozygous transposon insertion C. albicans orf19.1453 ORF SPT5 CAL0004616 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.1453 ORF SPT5 CAL0004616 PMID: 12773383|CGD_REF: CAL0087974 heterozygous diploid, classical genetics (haploinsufficient phenotype assay) null CAI-4 filamentous growth: decreased solid Spider medium heterozygous transposon insertion C. albicans orf19.1453 ORF SPT5 CAL0004616 PMID: 12773383|CGD_REF: CAL0087974 heterozygous diploid, classical genetics (haploinsufficient phenotype assay) unspecified CAI-4 filamentous growth: decreased solid Spider medium transposon insertion proximal to, but not within, the ORF C. albicans orf19.1457 ORF CAL0004620 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.1457 ORF CAL0004620 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 invasive growth: decreased solid SLAD media C. albicans orf19.1458 ORF CAL0004621 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.1459 ORF PPE1 CAL0004622 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.1460 ORF CAL0004651 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.1462 ORF SMP2 CAL0004653 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.1464 ORF BMT5 CAL0004654 PMID: 18234669|CGD_REF: CAL0119018 homozygous diploid, classical genetics null Not recorded resistance to chemicals: normal Calcofluor White C. albicans orf19.1464 ORF BMT5 CAL0004654 PMID: 18234669|CGD_REF: CAL0119018 homozygous diploid, classical genetics null Not recorded resistance to chemicals: normal sodium dodecyl sulfate C. albicans orf19.1464 ORF BMT5 CAL0004654 PMID: 18234669|CGD_REF: CAL0119018 homozygous diploid, classical genetics null BWP17 hyphal growth: normal serum-containing medium C. albicans orf19.1464 ORF BMT5 CAL0004654 PMID: 18234669|CGD_REF: CAL0119018 homozygous diploid, classical genetics null Not recorded viable rich medium wild-type growth rate C. albicans orf19.1464 ORF BMT5 CAL0004654 PMID: 18234669|CGD_REF: CAL0119018 homozygous diploid, classical genetics null Not recorded chlamydospore formation: normal RAT medium C. albicans orf19.1464 ORF BMT5 CAL0004654 PMID: 18234669|CGD_REF: CAL0119018 homozygous diploid, classical genetics null Not recorded ionic stress resistance: normal sodium chloride C. albicans orf19.1464 ORF BMT5 CAL0004654 PMID: 18234669|CGD_REF: CAL0119018 homozygous diploid, classical genetics null Not recorded resistance to chemicals: normal calcium dichloride C. albicans orf19.1465 ORF CAL0004655 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.1466 ORF REX2 CAL0004656 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.1468 ORF CDC55 CAL0004658 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.147 ORF YAK1 CAL0003123 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.147 ORF YAK1 CAL0003123 PMID: 18321992|CGD_REF: CAL0118911 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.147 ORF YAK1 CAL0003123 PMID: 18321992|CGD_REF: CAL0118911 homozygous diploid, classical genetics null BWP17 biofilm formation: decreased C. albicans orf19.147 ORF YAK1 CAL0003123 PMID: 18321992|CGD_REF: CAL0118911 heterozygous diploid, classical genetics conditional yak1-F507A BWP17 hyphal growth: decreased decreased hyphal formation, elongation and maintenance C. albicans orf19.147 ORF YAK1 CAL0003123 PMID: 18321992|CGD_REF: CAL0118911 homozygous diploid, classical genetics null BWP17 filamentous growth: decreased C. albicans orf19.147 ORF YAK1 CAL0003123 PMID: 18321992|CGD_REF: CAL0118911 homozygous diploid, classical genetics null Not recorded virulence: normal mouse intravenous infection C. albicans orf19.147 ORF YAK1 CAL0003123 PMID: 18321992|CGD_REF: CAL0118911 homozygous diploid, classical genetics null Not recorded virulence: normal mouse oropharyngeal infection C. albicans orf19.1470 ORF RPS26A CAL0004688 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient YPD medium C. albicans orf19.1470 ORF RPS26A CAL0004688 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient SC medium C. albicans orf19.1470 ORF RPS26A CAL0004688 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient YNB medium C. albicans orf19.1470 ORF RPS26A CAL0004688 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient SLAD medium C. albicans orf19.1471 ORF COX4 CAL0004689 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.1471 ORF COX4 CAL0004689 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: abnormal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.1471 ORF COX4 CAL0004689 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: decreased rate liquid synthetic complete medium C. albicans orf19.1471 ORF COX4 CAL0004689 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.1474 ORF SLA1 CAL0004691 PMID: 22787279|CGD_REF: CAL0000157581 homozygous diploid, classical genetics null sla1-13E/sla1-13E (phosphomimetic mutation yields same results as null) BWP17 filamentous growth: decreased serum-containing solid medium at 37 deg C. albicans orf19.1474 ORF SLA1 CAL0004691 PMID: 22787279|CGD_REF: CAL0000157581 homozygous diploid, classical genetics null sla1-13E/sla1-13E (phosphomimetic mutation yields same results as null) BWP17 heat sensitivity: increased lost viability at 42 deg C. albicans orf19.1474 ORF SLA1 CAL0004691 PMID: 22787279|CGD_REF: CAL0000157581 homozygous diploid, classical genetics null sla1-13E/sla1-13E (phosphomimetic mutation yields same results as null) BWP17 actin cytoskeleton morphology: abnormal C. albicans orf19.1474 ORF SLA1 CAL0004691 PMID: 22787279|CGD_REF: CAL0000157581 homozygous diploid, classical genetics null sla1-13E/sla1-13E (phosphomimetic mutation yields same results as null) BWP17 endocytosis: decreased C. albicans orf19.1474 ORF SLA1 CAL0004691 PMID: 20383711|CGD_REF: CAL0125351 homozygous diploid, classical genetics null sla1::CdHIS1/sla1::URA3 SC5314 viable C. albicans orf19.1474 ORF SLA1 CAL0004691 PMID: 20383711|CGD_REF: CAL0125351 homozygous diploid, classical genetics null sla1::CdHIS1/sla1::URA3 SC5314 hyphal growth: abnormal serum-containing or Spider medium shorter hyphae C. albicans orf19.1474 ORF SLA1 CAL0004691 PMID: 20383711|CGD_REF: CAL0125351 homozygous diploid, classical genetics null sla1::CdHIS1/sla1::URA3 SC5314 actin cytoskeleton morphology: abnormal defects in actin patch assembly and distribution C. albicans orf19.1474 ORF SLA1 CAL0004691 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient YPD medium C. albicans orf19.1477 ORF CAL0004693 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.1477 ORF CAL0004693 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 invasive growth: decreased solid SLAD media C. albicans orf19.1478 ORF STT3 CAL0004694 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.1479 ORF CAL0004695 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 invasive growth: decreased solid SLAD media C. albicans orf19.1480 ORF CAL0004732 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.1481 ORF HAP42 CAL0004733 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 invasive growth: decreased solid SLAD media C. albicans orf19.1488 ORF CAL0004740 PMID: 20384695|CGD_REF: CAL0125373 homozygous diploid, classical genetics null BWP17 viable C. albicans orf19.1490 ORF MSB2 CAL0004775 PMID: 19542310|CGD_REF: CAL0123805 homozygous diploid, classical genetics null Not recorded resistance to enzymatic treatment: decreased zymolyase C. albicans orf19.1490 ORF MSB2 CAL0004775 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.1490 ORF MSB2 CAL0004775 PMID: 17873081|CGD_REF: CAL0118685 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.1490 ORF MSB2 CAL0004775 PMID: 19542310|CGD_REF: CAL0123805 homozygous diploid, classical genetics null RM1000 filamentous growth: decreased sucrose or mannitol carbon sources, or under hypoxic condition C. albicans orf19.1490 ORF MSB2 CAL0004775 PMID: 17873081|CGD_REF: CAL0118685 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased caspofungin C. albicans orf19.1490 ORF MSB2 CAL0004775 PMID: 19542310|CGD_REF: CAL0123805 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased caspofungin C. albicans orf19.1490 ORF MSB2 CAL0004775 PMID: 19542310|CGD_REF: CAL0123805 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased Congo Red C. albicans orf19.1490 ORF MSB2 CAL0004775 PMID: 21375589|CGD_REF: CAL0141772 homozygous diploid, classical genetics null CAF2-1 resistance to chemicals: decreased tunicamycin C. albicans orf19.1490 ORF MSB2 CAL0004775 PMID: 21375589|CGD_REF: CAL0141772 homozygous diploid, classical genetics null CAF2-1 resistance to chemicals: decreased caspofungin C. albicans orf19.1490 ORF MSB2 CAL0004775 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: decreased growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.1490 ORF MSB2 CAL0004775 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: abnormal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.1490 ORF MSB2 CAL0004775 PMID: 23139737|CGD_REF: CAL0000158100 homozygous diploid, classical genetics null CAI-4 biofilm formation: decreased C. albicans orf19.1490 ORF MSB2 CAL0004775 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.1490 ORF MSB2 CAL0004775 PMID: 20384695|CGD_REF: CAL0125373 homozygous diploid, classical genetics null BWP17 invasive growth: delayed embedded agar conditions C. albicans orf19.1490 ORF MSB2 CAL0004775 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.1491 ORF CAL0004776 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.1491 ORF CAL0004776 PMID: 20494978|CGD_REF: CAL0125636 heterozygous diploid, classical genetics null BWP17 resistance to chemicals: decreased clotrimazole (75 uM) growth in liquid culture confirmation of mutant phenotypes for heterozygous transposon insertion strains showing sensitivity in a large-scale assay C. albicans orf19.1492 ORF PRP39 CAL0004777 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.1493 ORF RAD7 CAL0004778 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.1494 ORF RAD23 CAL0004779 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.1495 ORF CAL0004780 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.1496 ORF CAL0004781 PMID: 15964282|CGD_REF: CAL0114274 homozygous diploid, systematic mutation set (split-marker transposon insertion strategy to disrupt both alleles) null BWP17 viable C. albicans orf19.1496 ORF CAL0004781 PMID: 15964282|CGD_REF: CAL0114274 homozygous diploid, systematic mutation set (split-marker transposon insertion strategy to disrupt both alleles) null BWP17 biofilm formation: normal C. albicans orf19.1497 ORF ZCF6 CAL0004782 PMID: 15964282|CGD_REF: CAL0114274 homozygous diploid, systematic mutation set (split-marker transposon insertion strategy to disrupt both alleles) null BWP17 viable C. albicans orf19.1497 ORF ZCF6 CAL0004782 PMID: 15964282|CGD_REF: CAL0114274 homozygous diploid, systematic mutation set (split-marker transposon insertion strategy to disrupt both alleles) null BWP17 biofilm formation: normal C. albicans orf19.1497 ORF ZCF6 CAL0004782 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.1497 ORF ZCF6 CAL0004782 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.1497 ORF ZCF6 CAL0004782 PMID: 22073120|CGD_REF: CAL0000143592 homozygous diploid, classical genetics null BWP17 viable C. albicans orf19.1497 ORF ZCF6 CAL0004782 PMID: 22073120|CGD_REF: CAL0000143592 homozygous diploid, classical genetics null BWP17 colony appearance: abnormal increased colony wrinkling C. albicans orf19.1497 ORF ZCF6 CAL0004782 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.1497 ORF ZCF6 CAL0004782 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.1499 ORF CTF1 CAL0004783 PMID: 19700635|CGD_REF: CAL0124154 homozygous diploid, classical genetics null Not recorded utilization of carbon source: absent extra-virgin olive oil C. albicans orf19.1499 ORF CTF1 CAL0004783 PMID: 19700635|CGD_REF: CAL0124154 homozygous diploid, classical genetics null Not recorded utilization of carbon source: absent polysorbate 20 C. albicans orf19.1499 ORF CTF1 CAL0004783 PMID: 19700635|CGD_REF: CAL0124154 homozygous diploid, classical genetics null Not recorded utilization of carbon source: normal polysorbate 60 utilization of Tween 80 and Tween 85 is also wild-type C. albicans orf19.1499 ORF CTF1 CAL0004783 PMID: 18451058|CGD_REF: CAL0118988 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.1499 ORF CTF1 CAL0004783 PMID: 19700635|CGD_REF: CAL0124154 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.1499 ORF CTF1 CAL0004783 PMID: 19700635|CGD_REF: CAL0124154 homozygous diploid, classical genetics null Not recorded utilization of carbon source: absent oleic acid C. albicans orf19.1499 ORF CTF1 CAL0004783 PMID: 19700635|CGD_REF: CAL0124154 homozygous diploid, classical genetics null Not recorded utilization of carbon source: absent linoleic acid C. albicans orf19.1499 ORF CTF1 CAL0004783 PMID: 19700635|CGD_REF: CAL0124154 homozygous diploid, classical genetics null Not recorded virulence: decreased slight decrease mouse intravenous infection C. albicans orf19.150 ORF TIM17 CAL0003142 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.1502 ORF CAL0005380 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.1502 ORF CAL0005380 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: decreased rate liquid synthetic complete medium C. albicans orf19.1502 ORF CAL0005380 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.1502 ORF CAL0005380 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.1504 ORF CAL0005383 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.1505 ORF CAL0005385 PMID: 14663094|CGD_REF: CAL0080633 homozygous diploid, systematic mutation set (homozygous insertion mutants generated with URA3-ARG4-URA3 (UAU1) cassette) null BWP17 viable C. albicans orf19.1509 ORF ROD1 CAL0005393 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.1509 ORF ROD1 CAL0005393 PMID: 14663094|CGD_REF: CAL0080633 homozygous diploid, systematic mutation set (homozygous insertion mutants generated with URA3-ARG4-URA3 (UAU1) cassette) null BWP17 viable C. albicans orf19.151 ORF TPO5 CAL0003144 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.151 ORF TPO5 CAL0003144 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, competitive growth (haploinsufficient phenotype assay, barcode deletion set) null SC5314 resistance to chemicals: decreased ergosterol analogs (ECC69 and/or ECC1384) C. albicans orf19.1510 ORF SRD1 CAL0005401 PMID: 14663094|CGD_REF: CAL0080633 homozygous diploid, systematic mutation set (homozygous insertion mutants generated with URA3-ARG4-URA3 (UAU1) cassette) null BWP17 viable C. albicans orf19.1510 ORF SRD1 CAL0005401 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.1510 ORF SRD1 CAL0005401 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.1510 ORF SRD1 CAL0005401 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.1510 ORF SRD1 CAL0005401 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.1513 ORF FAB1 CAL0005404 PMID: 12117957|CGD_REF: CAL0081276 homozygous diploid, classical genetics null Not recorded heat sensitivity: normal C. albicans orf19.1513 ORF FAB1 CAL0005404 PMID: 19040629|CGD_REF: CAL0121263 heterozygous diploid, classical genetics repressible CAI-4 hyphal growth: abnormal altered branching frequency in hyphae C. albicans orf19.1513 ORF FAB1 CAL0005404 PMID: 12117957|CGD_REF: CAL0081276 homozygous diploid, classical genetics null CAI-4 hyphal growth: normal liquid Spider medium, or YPD medium plus serum C. albicans orf19.1513 ORF FAB1 CAL0005404 PMID: 12117957|CGD_REF: CAL0081276 homozygous diploid, classical genetics null CAI-4 hyphal growth: absent solid Spider medium plus mannitol C. albicans orf19.1513 ORF FAB1 CAL0005404 PMID: 12117957|CGD_REF: CAL0081276 homozygous diploid, classical genetics null CAI-4 hyphal growth: absent solid YPD media plus serum C. albicans orf19.1513 ORF FAB1 CAL0005404 PMID: 19040629|CGD_REF: CAL0121263 heterozygous diploid, classical genetics repressible Not recorded vacuolar morphology: abnormal decreased vacuole content C. albicans orf19.1513 ORF FAB1 CAL0005404 PMID: 19040629|CGD_REF: CAL0121263 heterozygous diploid, classical genetics repressible Not recorded vacuolar morphology: abnormal enlarged vacuoles, depleted in emerging buds in yeast-like cells C. albicans orf19.1513 ORF FAB1 CAL0005404 PMID: 12117957|CGD_REF: CAL0081276 homozygous diploid, classical genetics null Not recorded vacuolar morphology: abnormal vacuoles are enlarged C. albicans orf19.1513 ORF FAB1 CAL0005404 PMID: 12117957|CGD_REF: CAL0081276 homozygous diploid, classical genetics null Not recorded vacuolar transport: abnormal decreased vacuolar acidification C. albicans orf19.1513 ORF FAB1 CAL0005404 PMID: 12117957|CGD_REF: CAL0081276 homozygous diploid, classical genetics null Not recorded vegetative growth: decreased rate C. albicans orf19.1513 ORF FAB1 CAL0005404 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.1513 ORF FAB1 CAL0005404 PMID: 12117957|CGD_REF: CAL0081276 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.1513 ORF FAB1 CAL0005404 PMID: 12117957|CGD_REF: CAL0081276 homozygous diploid, classical genetics null Not recorded adhesion: normal adhesion to human epithelial (HeLa) cells C. albicans orf19.1513 ORF FAB1 CAL0005404 PMID: 12117957|CGD_REF: CAL0081276 homozygous diploid, classical genetics null Not recorded osmotic stress resistance: normal C. albicans orf19.1513 ORF FAB1 CAL0005404 PMID: 12117957|CGD_REF: CAL0081276 homozygous diploid, classical genetics null Not recorded cytokinesis: decreased increased proportion of binucleate cells C. albicans orf19.1513 ORF FAB1 CAL0005404 PMID: 19040629|CGD_REF: CAL0121263 heterozygous diploid, classical genetics repressible CAI-4 filamentous growth: abnormal agar-slide cultures with serum forms pseudohyphae instead of true hyphae C. albicans orf19.1513 ORF FAB1 CAL0005404 PMID: 12117957|CGD_REF: CAL0081276 homozygous diploid, classical genetics null Not recorded virulence: normal mouse intravenous infection C. albicans orf19.1514 ORF CAL0005407 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.1515 ORF CHT4 CAL0005409 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.1515 ORF CHT4 CAL0005409 PMID: 16214381|CGD_REF: CAL0114979 homozygous diploid, classical genetics null Not recorded viable no apparent phenotype C. albicans orf19.1515 ORF CHT4 CAL0005409 PMID: 16214381|CGD_REF: CAL0114979 heterozygous diploid, classical genetics null Not recorded viable C. albicans orf19.1515 ORF CHT4 CAL0005409 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.1515 ORF CHT4 CAL0005409 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.1515 ORF CHT4 CAL0005409 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.1515 ORF CHT4 CAL0005409 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.1516 ORF CAL0005412 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.1517 ORF ARO3 CAL0005414 PMID: 8625423|CGD_REF: CAL0080779 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.1523 ORF FMO1 CAL0005437 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.1523 ORF FMO1 CAL0005437 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, competitive growth (haploinsufficient phenotype assay, barcode deletion set) null SC5314 resistance to chemicals: decreased amphotericin B C. albicans orf19.1523 ORF FMO1 CAL0005437 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, competitive growth (haploinsufficient phenotype assay, barcode deletion set) null SC5314 resistance to chemicals: decreased ergosterol analogs (ECC69 and/or ECC1384) C. albicans orf19.1524 ORF SPR3 CAL0005440 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.1524 ORF SPR3 CAL0005440 PMID: 12181342|CGD_REF: CAL0080842 homozygous diploid, classical genetics null Not recorded viable no apparent phenotype C. albicans orf19.1524 ORF SPR3 CAL0005440 PMID: 16002645|CGD_REF: CAL0114398 homozygous diploid, classical genetics null Not recorded chlamydospore formation: normal C. albicans orf19.1526 ORF SNF2 CAL0005444 PMID: 16647065|CGD_REF: CAL0116010 homozygous diploid, classical genetics null CAI-4 hyphal growth: decreased serum-containing or Lee's medium, or solid media C. albicans orf19.1526 ORF SNF2 CAL0005444 PMID: 16647065|CGD_REF: CAL0116010 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.1526 ORF SNF2 CAL0005444 PMID: 16647065|CGD_REF: CAL0116010 homozygous diploid, classical genetics null Not recorded virulence: absent mouse intravenous infection C. albicans orf19.1531 ORF CAL0005466 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.1532 ORF SAM37 CAL0005468 PMID: 21299651|CGD_REF: CAL0141610 homozygous diploid, classical genetics null BWP17 viable C. albicans orf19.1532 ORF SAM37 CAL0005468 PMID: 21299651|CGD_REF: CAL0141610 homozygous diploid, classical genetics null BWP17 resistance to chemicals: decreased caspofungin C. albicans orf19.1532 ORF SAM37 CAL0005468 PMID: 22286093|CGD_REF: CAL0000143970 homozygous diploid, classical genetics null BWP17 mitochondrial distribution: abnormal C. albicans orf19.1532 ORF SAM37 CAL0005468 PMID: 22286093|CGD_REF: CAL0000143970 homozygous diploid, classical genetics null BWP17 cell wall morphology: abnormal C. albicans orf19.1532 ORF SAM37 CAL0005468 PMID: 22286093|CGD_REF: CAL0000143970 homozygous diploid, classical genetics null BWP17 virulence: decreased mouse intravenous infection C. albicans orf19.1536 ORF CAL0005476 PMID: 19779551|CGD_REF: CAL0124331 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.1536 ORF CAL0005476 PMID: 19779551|CGD_REF: CAL0124331 homozygous diploid, classical genetics null Not recorded colony appearance: abnormal solid Spider medium C. albicans orf19.1538 ORF TLG2 CAL0005480 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.154 ORF CAL0003149 PMID: 23572557|CGD_REF: CAL0000158900 homozygous diploid, classical genetics null orf19.154::Tn7-UAU1/orf19.3477::Tn7-URA3 BWP17 viable C. albicans orf19.154 ORF CAL0003149 PMID: 23572557|CGD_REF: CAL0000158900 homozygous diploid, classical genetics null BWP17 resistance to chemicals: increased fluconazole RPMI+MOPS+Histidine medium , 6 hours without shaking at 37 degrees C 24 hr fluconazole treatment in 96 well plates C. albicans orf19.1541 ORF CAL0005499 PMID: 14663094|CGD_REF: CAL0080633 homozygous diploid, systematic mutation set (homozygous insertion mutants generated with URA3-ARG4-URA3 (UAU1) cassette) null BWP17 viable C. albicans orf19.1542 ORF HEX3 CAL0005501 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.1542 ORF HEX3 CAL0005501 PMID: 12773383|CGD_REF: CAL0087974 heterozygous diploid, classical genetics (haploinsufficient phenotype assay) unspecified CAI-4 filamentous growth: decreased solid Spider medium transposon insertion proximal to, but not within, the ORF C. albicans orf19.1548 ORF CAL0005511 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.155 ORF URE2 CAL0003152 PMID: 21368275|CGD_REF: CAL0141755 haploid, classical genetics null Other C. albicans viable C. albicans orf19.1555 ORF SAC3 CAL0005530 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.1557 ORF CAL0005533 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 invasive growth: decreased solid SLAD media C. albicans orf19.1559 ORF HOM2 CAL0005534 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.156 ORF FGR51 CAL0003154 PMID: 12773383|CGD_REF: CAL0087974 heterozygous diploid, classical genetics (haploinsufficient phenotype assay) null CAI-4 viable heterozygous transposon insertion C. albicans orf19.156 ORF FGR51 CAL0003154 PMID: 12773383|CGD_REF: CAL0087974 heterozygous diploid, classical genetics (haploinsufficient phenotype assay) null CAI-4 filamentous growth: increased solid Spider medium heterozygous transposon insertion C. albicans orf19.156 ORF FGR51 CAL0003154 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.156 ORF FGR51 CAL0003154 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.156 ORF FGR51 CAL0003154 PMID: 12773383|CGD_REF: CAL0087974 heterozygous diploid, classical genetics (haploinsufficient phenotype assay) null CAI-4 colony size: decreased solid Spider medium heterozygous transposon insertion C. albicans orf19.156 ORF FGR51 CAL0003154 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.156 ORF FGR51 CAL0003154 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.156 ORF FGR51 CAL0003154 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 invasive growth: decreased solid SLAD media C. albicans orf19.1560 ORF POB3 CAL0005561 PMID: 12773383|CGD_REF: CAL0087974 heterozygous diploid, classical genetics (haploinsufficient phenotype assay) null CAI-4 viable heterozygous transposon insertion C. albicans orf19.1560 ORF POB3 CAL0005561 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.1560 ORF POB3 CAL0005561 PMID: 12773383|CGD_REF: CAL0087974 heterozygous diploid, classical genetics (haploinsufficient phenotype assay) null CAI-4 filamentous growth: increased solid Spider medium heterozygous transposon insertion C. albicans orf19.1560 ORF POB3 CAL0005561 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 invasive growth: decreased solid SLAD media C. albicans orf19.1563 ORF ECM3 CAL0005563 PMID: 17873081|CGD_REF: CAL0118685 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.1564 ORF CAL0005564 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.1565 ORF CAL0005565 PMID: 15964282|CGD_REF: CAL0114274 homozygous diploid, systematic mutation set (split-marker transposon insertion strategy to disrupt both alleles) null BWP17 viable C. albicans orf19.1565 ORF CAL0005565 PMID: 15964282|CGD_REF: CAL0114274 homozygous diploid, systematic mutation set (split-marker transposon insertion strategy to disrupt both alleles) null BWP17 biofilm formation: normal C. albicans orf19.1567 ORF CAL0005567 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: decreased growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.1567 ORF CAL0005567 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: abnormal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.1567 ORF CAL0005567 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: decreased rate liquid synthetic complete medium C. albicans orf19.1567 ORF CAL0005567 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.1569 ORF UTP22 CAL0005569 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.1569 ORF UTP22 CAL0005569 PMID: 19623926|CGD_REF: CAL0124054 heterozygous diploid, competitive growth (haploinsufficient phenotype assay, barcode deletion set) null SC5314 resistance to chemicals: increased parnafungin C. albicans orf19.1570 ORF ERG7 CAL0005598 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.1570 ORF ERG7 CAL0005598 PMID: 21135205|CGD_REF: CAL0139967 heterozygous diploid, large-scale survey (large-scale identification of genes essential for virulence in mouse) repressible CAI-4 virulence: absent mouse intravenous infection C. albicans orf19.1573 ORF CAL0005601 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.1573 ORF CAL0005601 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.1573 ORF CAL0005601 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.1573 ORF CAL0005601 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.1573 ORF CAL0005601 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.1574 ORF CAL0005602 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.1575 ORF PRS1 CAL0005603 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.1575 ORF PRS1 CAL0005603 PMID: 9402522|CGD_REF: CAL0081759 heterozygous diploid, classical genetics null Not recorded viable no apparent phenotype C. albicans orf19.1575 ORF PRS1 CAL0005603 PMID: 14507372|CGD_REF: CAL0088818 heterozygous diploid, large-scale survey (large-scale identification of essential genes by gene replacement and conditional expression (GRACE) method) repressible CAI-4 inviable one allele is deleted and the other is placed under repressible Tet promoter C. albicans orf19.1575 ORF PRS1 CAL0005603 PMID: 9402522|CGD_REF: CAL0081759 homozygous diploid, classical genetics null Not recorded inviable homozygous null mutant strain could not be recovered, suggesting that the gene is essential under the selection conditions C. albicans orf19.1575 ORF PRS1 CAL0005603 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, competitive growth (haploinsufficient phenotype assay, barcode deletion set) null SC5314 resistance to chemicals: decreased radicicol C. albicans orf19.1575 ORF PRS1 CAL0005603 PMID: 19115836|CGD_REF: CAL0122036 heterozygous diploid, competitive growth (haploinsufficient phenotype assay, barcode deletion set) null SC5314 resistance to chemicals: decreased radicicol C. albicans orf19.1575 ORF PRS1 CAL0005603 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, competitive growth (haploinsufficient phenotype assay, barcode deletion set) null SC5314 resistance to chemicals: decreased tunicamycin C. albicans orf19.1575 ORF PRS1 CAL0005603 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 invasive growth: decreased solid SLAD media C. albicans orf19.1576 ORF CAL0005604 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.1576 ORF CAL0005604 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.1576 ORF CAL0005604 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.1576 ORF CAL0005604 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.1576 ORF CAL0005604 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.1577 ORF CAL0005605 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.1577 ORF CAL0005605 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.1577 ORF CAL0005605 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.1577 ORF CAL0005605 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.1578 ORF CAL0005606 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.158 ORF CAL0003160 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.1580 ORF CAL0005638 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.1584 ORF CAL0005642 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.1584 ORF CAL0005642 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 invasive growth: decreased solid SLAD media C. albicans orf19.1585 ORF ZRT2 CAL0005643 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.1586 ORF FGR22 CAL0005644 PMID: 12773383|CGD_REF: CAL0087974 heterozygous diploid, classical genetics (haploinsufficient phenotype assay) null CAI-4 viable heterozygous deletion C. albicans orf19.1586 ORF FGR22 CAL0005644 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.1586 ORF FGR22 CAL0005644 PMID: 16207920|CGD_REF: CAL0114770 homozygous diploid, classical genetics null Not recorded viable minimal or rich media wild-type growth rate C. albicans orf19.1586 ORF FGR22 CAL0005644 PMID: 12773383|CGD_REF: CAL0087974 heterozygous diploid, classical genetics (haploinsufficient phenotype assay) null CAI-4 filamentous growth: increased solid Spider medium or solid YEPD plus serum heterozygous deletion C. albicans orf19.1586 ORF FGR22 CAL0005644 PMID: 12773383|CGD_REF: CAL0087974 heterozygous diploid, classical genetics (haploinsufficient phenotype assay) unspecified CAI-4 filamentous growth: increased solid Spider medium or solid YEPD plus serum transposon insertion proximal to, but not within, the ORF C. albicans orf19.1586 ORF FGR22 CAL0005644 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.1586 ORF FGR22 CAL0005644 PMID: 16040234|CGD_REF: CAL0114661 homozygous diploid, classical genetics null BWP17 resistance to killing by host cells: normal MOI of 0.1 in vitro model of infection (J774 macrophages) C. albicans orf19.1586 ORF FGR22 CAL0005644 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.1586 ORF FGR22 CAL0005644 PMID: 16040234|CGD_REF: CAL0114661 homozygous diploid, classical genetics null BWP17 resistance to phagocytosis: normal C. albicans orf19.1586 ORF FGR22 CAL0005644 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.1586 ORF FGR22 CAL0005644 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.1587 ORF HGT20 CAL0005645 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.1589 ORF CAL0005647 PMID: 17555439|CGD_REF: CAL0117968 homozygous diploid, classical genetics null Not recorded survival rate in stationary phase: decreased C. albicans orf19.1589 ORF CAL0005647 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.1589 ORF CAL0005647 PMID: 15964282|CGD_REF: CAL0114274 homozygous diploid, systematic mutation set (split-marker transposon insertion strategy to disrupt both alleles) null BWP17 viable C. albicans orf19.1589 ORF CAL0005647 PMID: 15964282|CGD_REF: CAL0114274 homozygous diploid, systematic mutation set (split-marker transposon insertion strategy to disrupt both alleles) null BWP17 biofilm formation: normal C. albicans orf19.1591 ORF ERG10 CAL0005678 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.1591 ORF ERG10 CAL0005678 PMID: 21135205|CGD_REF: CAL0139967 heterozygous diploid, large-scale survey (large-scale identification of genes essential for virulence in mouse) repressible CAI-4 virulence: absent mouse intravenous infection C. albicans orf19.1596 ORF FGR28 CAL0005683 PMID: 12773383|CGD_REF: CAL0087974 heterozygous diploid, classical genetics (haploinsufficient phenotype assay) unspecified CAI-4 filamentous growth: increased solid Spider medium or solid YEPD plus serum transposon insertion proximal to, but not within, the ORF C. albicans orf19.1596 ORF FGR28 CAL0005683 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 invasive growth: decreased solid SLAD media C. albicans orf19.1597 ORF ABG1 CAL0005684 PMID: 15947201|CGD_REF: CAL0114269 heterozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased Calcofluor White C. albicans orf19.1597 ORF ABG1 CAL0005684 PMID: 15947201|CGD_REF: CAL0114269 heterozygous diploid, classical genetics repressible Not recorded resistance to chemicals: decreased Calcofluor White C. albicans orf19.1597 ORF ABG1 CAL0005684 PMID: 15947201|CGD_REF: CAL0114269 heterozygous diploid, classical genetics repressible Not recorded resistance to chemicals: increased sodium dodecyl sulfate C. albicans orf19.1597 ORF ABG1 CAL0005684 PMID: 15947201|CGD_REF: CAL0114269 heterozygous diploid, classical genetics repressible CAI-4 hyphal growth: abnormal increased branching frequency under hyphae-inducing conditions C. albicans orf19.1597 ORF ABG1 CAL0005684 PMID: 15947201|CGD_REF: CAL0114269 heterozygous diploid, classical genetics repressible Not recorded vacuolar morphology: abnormal small, collapsed vacuole in yeast-form; small, fragmented vacuole in hyphal form C. albicans orf19.1597 ORF ABG1 CAL0005684 PMID: 15947201|CGD_REF: CAL0114269 heterozygous diploid, classical genetics overexpression Not recorded viable no apparent phenotype C. albicans orf19.1597 ORF ABG1 CAL0005684 PMID: 15947201|CGD_REF: CAL0114269 heterozygous diploid, classical genetics null Not recorded viable C. albicans orf19.1597 ORF ABG1 CAL0005684 PMID: 15947201|CGD_REF: CAL0114269 homozygous diploid, classical genetics null Not recorded inviable homozygous null mutant strain could not be recovered, suggesting that the gene is essential under the selection conditions C. albicans orf19.1597 ORF ABG1 CAL0005684 PMID: 15947201|CGD_REF: CAL0114269 heterozygous diploid, classical genetics repressible Not recorded inviable C. albicans orf19.1597 ORF ABG1 CAL0005684 PMID: 15947201|CGD_REF: CAL0114269 heterozygous diploid, classical genetics repressible Not recorded cellular morphology: abnormal budded daughter cells fail to separate; chains of cells of decreasing size are observed under conditions that favor yeast-form growth C. albicans orf19.1597 ORF ABG1 CAL0005684 PMID: 15947201|CGD_REF: CAL0114269 heterozygous diploid, classical genetics null Not recorded cytokinesis: absent budded daughter cells fail to separate; chains of cells of decreasing size are observed under conditions that favor yeast-form growth C. albicans orf19.1597 ORF ABG1 CAL0005684 PMID: 15947201|CGD_REF: CAL0114269 heterozygous diploid, classical genetics repressible Not recorded resistance to chemicals: decreased Congo Red C. albicans orf19.1597 ORF ABG1 CAL0005684 PMID: 19175413|CGD_REF: CAL0000142479 heterozygous diploid, classical genetics repressible abg1::HisG/abg1::URA3-MET3p-ABG1 (repressible by methionine) CAI-4 endocytosis: decreased lucifer yellow assay for endocytosis C. albicans orf19.1598 ORF ERG24 CAL0005685 PMID: 11897574|CGD_REF: CAL0081256 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased brefeldin A C. albicans orf19.1598 ORF ERG24 CAL0005685 PMID: 11897574|CGD_REF: CAL0081256 homozygous diploid, classical genetics null Not recorded germ tube formation: absent serum-containing medium C. albicans orf19.1598 ORF ERG24 CAL0005685 PMID: 11897574|CGD_REF: CAL0081256 homozygous diploid, classical genetics null Not recorded vegetative growth: decreased rate C. albicans orf19.1598 ORF ERG24 CAL0005685 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.1598 ORF ERG24 CAL0005685 PMID: 14507372|CGD_REF: CAL0088818 heterozygous diploid, large-scale survey (large-scale identification of essential genes by gene replacement and conditional expression (GRACE) method) repressible CAI-4 viable one allele is deleted and the other is placed under repressible Tet promoter C. albicans orf19.1598 ORF ERG24 CAL0005685 PMID: 11897574|CGD_REF: CAL0081256 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.1598 ORF ERG24 CAL0005685 PMID: 11897574|CGD_REF: CAL0081256 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased cycloheximide C. albicans orf19.1598 ORF ERG24 CAL0005685 PMID: 11897574|CGD_REF: CAL0081256 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased cerulenin C. albicans orf19.1598 ORF ERG24 CAL0005685 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, competitive growth (haploinsufficient phenotype assay, barcode deletion set) null SC5314 resistance to chemicals: decreased dyclonine C. albicans orf19.1598 ORF ERG24 CAL0005685 PMID: 11897574|CGD_REF: CAL0081256 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased fluphenazine C. albicans orf19.1598 ORF ERG24 CAL0005685 PMID: 11897574|CGD_REF: CAL0081256 homozygous diploid, classical genetics null Not recorded resistance to chemicals: increased triazoles C. albicans orf19.1598 ORF ERG24 CAL0005685 PMID: 11897574|CGD_REF: CAL0081256 homozygous diploid, classical genetics null Not recorded virulence: decreased mouse intravenous infection C. albicans orf19.1598 ORF ERG24 CAL0005685 PMID: 21135205|CGD_REF: CAL0139967 heterozygous diploid, competitive growth (large-scale identification of genes essential for virulence in mouse) repressible CAI-4 virulence: decreased mouse intravenous infection C. albicans orf19.1601 ORF RPL3 CAL0006304 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.1605 ORF PMS1 CAL0006312 PMID: 17965250|CGD_REF: CAL0118884 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.1607 ORF ALR1 CAL0006317 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.1607 ORF ALR1 CAL0006317 PMID: 21135205|CGD_REF: CAL0139967 heterozygous diploid, competitive growth (large-scale identification of genes essential for virulence in mouse) repressible CAI-4 virulence: decreased mouse intravenous infection C. albicans orf19.1608 ORF CAL0006319 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.1609 ORF CAL0006321 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.1613 ORF ILV2 CAL0006335 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.1613 ORF ILV2 CAL0006335 PMID: 20019084|CGD_REF: CAL0124886 homozygous diploid, classical genetics null ilv2::SAT1/ilv2::FRT SC5314 viable C. albicans orf19.1613 ORF ILV2 CAL0006335 PMID: 20019084|CGD_REF: CAL0124886 homozygous diploid, classical genetics null ilv2::SAT1/ilv2::FRT SC5314 virulence: decreased mouse intravenous infection C. albicans orf19.1613 ORF ILV2 CAL0006335 PMID: 20019084|CGD_REF: CAL0124886 homozygous diploid, classical genetics null ilv2::SAT1/ilv2::FRT SC5314 starvation resistance: decreased mutant cells lose viability upon isoleucine and valine starvation C. albicans orf19.1614 ORF MEP1 CAL0006337 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.1614 ORF MEP1 CAL0006337 PMID: 14663094|CGD_REF: CAL0080633 homozygous diploid, systematic mutation set (homozygous insertion mutants generated with URA3-ARG4-URA3 (UAU1) cassette) null BWP17 viable C. albicans orf19.1614 ORF MEP1 CAL0006337 PMID: 15819622|CGD_REF: CAL0104067 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.1614 ORF MEP1 CAL0006337 PMID: 15819622|CGD_REF: CAL0104067 homozygous diploid, classical genetics null CAI-4 filamentous growth: normal C. albicans orf19.1616 ORF FGR23 CAL0006341 PMID: 18765290|CGD_REF: CAL0119430 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.1616 ORF FGR23 CAL0006341 PMID: 12773383|CGD_REF: CAL0087974 heterozygous diploid, classical genetics (haploinsufficient phenotype assay) null CAI-4 filamentous growth: decreased solid Spider medium heterozygous transposon insertion C. albicans orf19.1617 ORF CAL0006342 PMID: 12773383|CGD_REF: CAL0087974 heterozygous diploid, classical genetics (haploinsufficient phenotype assay) null CAI-4 filamentous growth: decreased solid Spider medium heterozygous transposon insertion C. albicans orf19.1617 ORF CAL0006342 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient SLAD medium C. albicans orf19.1618 ORF GFA1 CAL0006344 PMID: 15158264|CGD_REF: CAL0081352 heterozygous diploid, classical genetics null CAI-4 germ tube formation: decreased Lee's or GlcNAc-containing media at 37 deg C C. albicans orf19.1618 ORF GFA1 CAL0006344 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.1618 ORF GFA1 CAL0006344 PMID: 15158264|CGD_REF: CAL0081352 heterozygous diploid, classical genetics null Not recorded viable C. albicans orf19.1618 ORF GFA1 CAL0006344 PMID: 15158264|CGD_REF: CAL0081352 heterozygous diploid, classical genetics reduction of function gfa1-S208A (lacks phosphorylation site) CAI-4 germ tube formation: abnormal Lee's, serum- or GlcNAc-containing media at 37 deg C germ tube formation is decreased while pseudohyphal growth is increased C. albicans orf19.1618 ORF GFA1 CAL0006344 PMID: 15158264|CGD_REF: CAL0081352 heterozygous diploid, classical genetics reduction of function gfa1-S208A (lacks phosphorylation site) Not recorded viable C. albicans orf19.1618 ORF GFA1 CAL0006344 PMID: 15158264|CGD_REF: CAL0081352 homozygous diploid, classical genetics null Not recorded inviable viability is rescued by GlcNAc C. albicans orf19.1618 ORF GFA1 CAL0006344 PMID: 9933591|CGD_REF: CAL0081350 homozygous diploid, classical genetics null Not recorded inviable C. albicans orf19.1618 ORF GFA1 CAL0006344 PMID: 15158264|CGD_REF: CAL0081352 heterozygous diploid, classical genetics reduction of function Not recorded chitin deposition: abnormal 37 deg C altered chitin content and decreased induction of chitin synthesis C. albicans orf19.1618 ORF GFA1 CAL0006344 PMID: 21135205|CGD_REF: CAL0139967 heterozygous diploid, large-scale survey (large-scale identification of genes essential for virulence in mouse) repressible CAI-4 virulence: absent mouse intravenous infection C. albicans orf19.1619 ORF CAL0006346 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.1621 ORF GPA2 CAL0006364 PMID: 12477787|CGD_REF: CAL0081356 homozygous diploid, classical genetics null CAI-4 germ tube formation: absent liquid Spider medium, Lee's medium at pH 7, solid SLAD medium, or in embedded conditions blocked yeast-to-hyphae switch in C. albicans orf19.1621 ORF GPA2 CAL0006364 PMID: 15673611|CGD_REF: CAL0082754 homozygous diploid, classical genetics null CAI-4 hyphal growth: abnormal defect in embedded hyphal growth is rescued by cAMP, in contrast to a different published gpa2 mutant C. albicans orf19.1621 ORF GPA2 CAL0006364 PMID: 12477787|CGD_REF: CAL0081356 heterozygous diploid, classical genetics dominant negative CAI-4 hyphal growth: absent liquid Spider and Lee's pH 7 media C. albicans orf19.1621 ORF GPA2 CAL0006364 PMID: 15302825|CGD_REF: CAL0082074 heterozygous diploid, classical genetics activation CAI-4 hyphal growth: delayed liquid serum-containing medium C. albicans orf19.1621 ORF GPA2 CAL0006364 PMID: 15302825|CGD_REF: CAL0082074 homozygous diploid, classical genetics null CAI-4 hyphal growth: normal liquid serum-containing medium C. albicans orf19.1621 ORF GPA2 CAL0006364 PMID: 15302825|CGD_REF: CAL0082074 homozygous diploid, classical genetics null CAI-4 hyphal growth: decreased liquid Spider medium C. albicans orf19.1621 ORF GPA2 CAL0006364 PMID: 15302825|CGD_REF: CAL0082074 heterozygous diploid, classical genetics null Not recorded viable C. albicans orf19.1621 ORF GPA2 CAL0006364 PMID: 15302825|CGD_REF: CAL0082074 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.1621 ORF GPA2 CAL0006364 PMID: 15673611|CGD_REF: CAL0082754 heterozygous diploid, classical genetics null Not recorded viable C. albicans orf19.1621 ORF GPA2 CAL0006364 PMID: 15673611|CGD_REF: CAL0082754 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.1621 ORF GPA2 CAL0006364 PMID: 15673611|CGD_REF: CAL0082754 heterozygous diploid, classical genetics activation gpa2-Q355L Not recorded viable C. albicans orf19.1621 ORF GPA2 CAL0006364 PMID: 15302825|CGD_REF: CAL0082074 heterozygous diploid, classical genetics activation gpa2-Q355L Not recorded virulence: decreased mouse intravenous infection C. albicans orf19.1621 ORF GPA2 CAL0006364 PMID: 12477787|CGD_REF: CAL0081356 heterozygous diploid, classical genetics dominant negative CAI-4 invasive growth: absent embedded in solid SLAD medium C. albicans orf19.1621 ORF GPA2 CAL0006364 PMID: 15302825|CGD_REF: CAL0082074 homozygous diploid, classical genetics null CAI-4 invasive growth: decreased embedded in agar C. albicans orf19.1621 ORF GPA2 CAL0006364 PMID: 15302825|CGD_REF: CAL0082074 homozygous diploid, classical genetics null CAI-4 filamentous growth: decreased solid FBS or Spider media decreased filamentation is suppressed by dbcAMP (cAMP derivative) C. albicans orf19.1621 ORF GPA2 CAL0006364 PMID: 15302825|CGD_REF: CAL0082074 heterozygous diploid, classical genetics activation CAI-4 filamentous growth: increased C. albicans orf19.1621 ORF GPA2 CAL0006364 PMID: 16987174|CGD_REF: CAL0116689 homozygous diploid, classical genetics null Not recorded pheromone sensitivity: increased alpha factor C. albicans orf19.1621 ORF GPA2 CAL0006364 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: decreased growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.1621 ORF GPA2 CAL0006364 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: abnormal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.1621 ORF GPA2 CAL0006364 PMID: 15302825|CGD_REF: CAL0082074 heterozygous diploid, classical genetics null Not recorded virulence: normal mouse intravenous infection C. albicans orf19.1621 ORF GPA2 CAL0006364 PMID: 15302825|CGD_REF: CAL0082074 homozygous diploid, classical genetics null Not recorded virulence: normal mouse intravenous infection C. albicans orf19.1621 ORF GPA2 CAL0006364 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.1621 ORF GPA2 CAL0006364 PMID: 20558315|CGD_REF: CAL0125518 homozygous diploid, classical genetics null CAF2-1 chemical compound accumulation: decreased 3',5'-cyclic AMP fails to accumulate cAMP in response to glucose addition to glucose-starved cells C. albicans orf19.1621 ORF GPA2 CAL0006364 PMID: 20558315|CGD_REF: CAL0125518 homozygous diploid, classical genetics null CAF2-1 filamentous growth: decreased embedded in YPS or Spider agar C. albicans orf19.1621 ORF GPA2 CAL0006364 PMID: 20558315|CGD_REF: CAL0125518 homozygous diploid, classical genetics null CAF2-1 cold sensitivity: increased reduced temperature (25 deg C) C. albicans orf19.1621 ORF GPA2 CAL0006364 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.1622 ORF YCG1 CAL0006366 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.1623 ORF CAP1 CAL0006368 PMID: 9922230|CGD_REF: CAL0080811 aneuploid, classical genetics activation Not recorded resistance to chemicals: increased brefeldin A C. albicans orf19.1623 ORF CAP1 CAL0006368 PMID: 9922230|CGD_REF: CAL0080811 aneuploid, classical genetics activation Not recorded resistance to chemicals: increased 1,1'-azobis(N,N-dimethylformamide) C. albicans orf19.1623 ORF CAP1 CAL0006368 PMID: 20041210|CGD_REF: CAL0124764 homozygous diploid, systematic mutation set null SN152 resistance to chemicals: decreased flucytosine strongly sensitive C. albicans orf19.1623 ORF CAP1 CAL0006368 PMID: 15964282|CGD_REF: CAL0114274 homozygous diploid, systematic mutation set (split-marker transposon insertion strategy to disrupt both alleles) null BWP17 viable C. albicans orf19.1623 ORF CAP1 CAL0006368 PMID: 12684384|CGD_REF: CAL0080816 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.1623 ORF CAP1 CAL0006368 PMID: 9922230|CGD_REF: CAL0080811 aneuploid, classical genetics activation Not recorded viable C. albicans orf19.1623 ORF CAP1 CAL0006368 PMID: 9922230|CGD_REF: CAL0080811 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.1623 ORF CAP1 CAL0006368 PMID: 19734718|CGD_REF: CAL0124171 heterozygous diploid, classical genetics overexpression Not recorded apoptosis: decreased apoptotic response to Baicalein (BE) is less severe than in wild type C. albicans orf19.1623 ORF CAP1 CAL0006368 PMID: 19734718|CGD_REF: CAL0124171 homozygous diploid, classical genetics null Not recorded apoptosis: abnormal apoptotic response to Baicalein (BE) is more severe than in wild type C. albicans orf19.1623 ORF CAP1 CAL0006368 PMID: 15964282|CGD_REF: CAL0114274 homozygous diploid, systematic mutation set (split-marker transposon insertion strategy to disrupt both alleles) null BWP17 biofilm formation: normal C. albicans orf19.1623 ORF CAP1 CAL0006368 PMID: 16339080|CGD_REF: CAL0115439 homozygous diploid, classical genetics null Not recorded oxidative stress resistance: decreased hydrogen peroxide increased sensitivity to high- or low-dose peroxide stress C. albicans orf19.1623 ORF CAP1 CAL0006368 PMID: 12684384|CGD_REF: CAL0080816 homozygous diploid, classical genetics null Not recorded oxidative stress resistance: decreased hydrogen peroxide C. albicans orf19.1623 ORF CAP1 CAL0006368 PMID: 18310903|CGD_REF: CAL0118908 homozygous diploid, classical genetics null Not recorded oxidative stress resistance: decreased hydrogen peroxide C. albicans orf19.1623 ORF CAP1 CAL0006368 PMID: 9922230|CGD_REF: CAL0080811 homozygous diploid, classical genetics null Not recorded oxidative stress resistance: decreased hydrogen peroxide C. albicans orf19.1623 ORF CAP1 CAL0006368 PMID: 20041210|CGD_REF: CAL0124764 homozygous diploid, systematic mutation set null SN152 oxidative stress resistance: decreased hydrogen peroxide severely sensitive C. albicans orf19.1623 ORF CAP1 CAL0006368 PMID: 9922230|CGD_REF: CAL0080811 aneuploid, classical genetics activation Not recorded resistance to chemicals: increased 4-nitroquinoline N-oxide C. albicans orf19.1623 ORF CAP1 CAL0006368 PMID: 9922230|CGD_REF: CAL0080811 homozygous diploid, classical genetics null Not recorded resistance to chemicals: increased 4-nitroquinoline N-oxide C. albicans orf19.1623 ORF CAP1 CAL0006368 PMID: 12684384|CGD_REF: CAL0080816 homozygous diploid, classical genetics null Not recorded metal resistance: decreased cadmium C. albicans orf19.1623 ORF CAP1 CAL0006368 PMID: 9922230|CGD_REF: CAL0080811 homozygous diploid, classical genetics null Not recorded metal resistance: increased cadmium C. albicans orf19.1623 ORF CAP1 CAL0006368 PMID: 9922230|CGD_REF: CAL0080811 aneuploid, classical genetics activation Not recorded resistance to chemicals: increased cadmium C. albicans orf19.1623 ORF CAP1 CAL0006368 PMID: 18310903|CGD_REF: CAL0118908 homozygous diploid, classical genetics null Not recorded chemical compound accumulation: increased trehalose C. albicans orf19.1623 ORF CAP1 CAL0006368 PMID: 9922230|CGD_REF: CAL0080811 aneuploid, classical genetics activation Not recorded resistance to chemicals: increased cerulenin C. albicans orf19.1623 ORF CAP1 CAL0006368 PMID: 20041210|CGD_REF: CAL0124764 homozygous diploid, systematic mutation set null SN152 oxidative stress resistance: decreased menadione strongly sensitive C. albicans orf19.1623 ORF CAP1 CAL0006368 PMID: 9922230|CGD_REF: CAL0080811 aneuploid, classical genetics activation Not recorded resistance to chemicals: increased 1,10-phenanthroline C. albicans orf19.1623 ORF CAP1 CAL0006368 PMID: 9922230|CGD_REF: CAL0080811 homozygous diploid, classical genetics null Not recorded resistance to chemicals: increased 1,10-phenanthroline C. albicans orf19.1623 ORF CAP1 CAL0006368 PMID: 9922230|CGD_REF: CAL0080811 aneuploid, classical genetics activation Not recorded resistance to chemicals: increased fluconazole C. albicans orf19.1623 ORF CAP1 CAL0006368 PMID: 9922230|CGD_REF: CAL0080811 homozygous diploid, classical genetics null Not recorded resistance to chemicals: normal fluconazole C. albicans orf19.1623 ORF CAP1 CAL0006368 PMID: 15813733|CGD_REF: CAL0104041 homozygous diploid, classical genetics null CAI-4 resistance to killing by host cells: decreased decreased viability in the presence of blood components in vitro model of infection (human whole blood or neutrophils) C. albicans orf19.1623 ORF CAP1 CAL0006368 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.1623 ORF CAP1 CAL0006368 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.1623 ORF CAP1 CAL0006368 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.1623 ORF CAP1 CAL0006368 PMID: 23314569|CGD_REF: CAL0000158454 homozygous diploid, classical genetics null Other C. albicans virulence: decreased mutants fail to cause disease and death in Caenorhabditis elegans except in bli-3 mutant worms that do not produce ROS because of a defective NADPH oxidase gene C. elegans infection C. albicans orf19.1623 ORF CAP1 CAL0006368 PMID: 23314569|CGD_REF: CAL0000158454 homozygous diploid, classical genetics null Other C. albicans resistance to killing by host cells: decreased chemical inhibition of the NADPH oxidase in cultured macrophages enabled the susceptible cap1 mutant to resists ROS-mediated phagolysis in vitro model of infection (cultured macrophages) C. albicans orf19.1623 ORF CAP1 CAL0006368 PMID: 23517286|CGD_REF: CAL0000158757 homozygous diploid, classical genetics null cap1::hisG/cap1::hisG/URA3 CAF2-1 chemical compound accumulation: increased intracellular ROS amphotericin B (AMB), acetic acid (AA) and hydrogen peroxide C. albicans orf19.1623 ORF CAP1 CAL0006368 PMID: 23517286|CGD_REF: CAL0000158757 homozygous diploid, classical genetics null cap1::hisG/cap1::hisG/URA3 CAF2-1 protein activity: increased amphotericin B (AMB), acetic acid (AA) and hydrogen peroxide caspase C. albicans orf19.1623 ORF CAP1 CAL0006368 PMID: 23517286|CGD_REF: CAL0000158757 homozygous diploid, classical genetics null cap1::hisG/cap1::hisG/URA3 CAF2-1 apoptosis: increased amphotericin B (AMB), acetic acid (AA) and hydrogen peroxide after AMB, AA and H2O2 treatment, more necrotic cells were observed in the mutant compared to wild-type C. albicans orf19.1623 ORF CAP1 CAL0006368 PMID: 23517286|CGD_REF: CAL0000158757 homozygous diploid, classical genetics null cap1::hisG/cap1::hisG/URA3 CAF2-1 RNA accumulation: increased amphotericin B (AMB), acetic acid (AA) and hydrogen peroxide metacaspase MCA1 C. albicans orf19.1623 ORF CAP1 CAL0006368 PMID: 23517286|CGD_REF: CAL0000158757 homozygous diploid, classical genetics null cap1::hisG/cap1::hisG/URA3 CAF2-1 RNA accumulation: decreased amphotericin B (AMB), acetic acid (AA) and hydrogen peroxide glutathione reductase, catalyzes the reduction of glutathione disulfide to provide glutathione GLR1 C. albicans orf19.1623 ORF CAP1 CAL0006368 PMID: 23706023|CGD_REF: CAL0000172371 homozygous diploid, classical genetics null Other C. albicans resistance to phagocytosis: decreased decreased killing of J774.1 macrophages after 3 hrs C. albicans orf19.1623 ORF CAP1 CAL0006368 PMID: 23706023|CGD_REF: CAL0000172371 homozygous diploid, classical genetics null Other C. albicans virulence: normal mouse intravenous infection C. albicans orf19.1623 ORF CAP1 CAL0006368 PMID: 23706023|CGD_REF: CAL0000172371 homozygous diploid, classical genetics null Other C. albicans virulence: decreased insect infection (Galleria mellonella survival model) C. albicans orf19.1623 ORF CAP1 CAL0006368 PMID: 20017731|CGD_REF: CAL0124891 homozygous diploid, classical genetics null Other C. albicans resistance to chemicals: decreased cucurminoids (74 mg/l) C. albicans orf19.1623 ORF CAP1 CAL0006368 PMID: 20608985|CGD_REF: CAL0125886 homozygous diploid, classical genetics null RM1000 resistance to chemicals: decreased menadione C. albicans orf19.1623 ORF CAP1 CAL0006368 PMID: 20608985|CGD_REF: CAL0125886 homozygous diploid, classical genetics null RM1000 oxidative stress resistance: decreased menadione C. albicans orf19.1623 ORF CAP1 CAL0006368 PMID: 20608985|CGD_REF: CAL0125886 homozygous diploid, classical genetics null RM1000 resistance to chemicals: decreased hydrogen peroxide C. albicans orf19.1623 ORF CAP1 CAL0006368 PMID: 20608985|CGD_REF: CAL0125886 homozygous diploid, classical genetics null RM1000 oxidative stress resistance: decreased hydrogen peroxide C. albicans orf19.1623 ORF CAP1 CAL0006368 PMID: 20608985|CGD_REF: CAL0125886 homozygous diploid, classical genetics null RM1000 chemical compound accumulation: increased trehalose C. albicans orf19.1623 ORF CAP1 CAL0006368 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.1625 ORF CAL0006373 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: decreased rate liquid synthetic complete medium C. albicans orf19.1625 ORF CAL0006373 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.1625 ORF CAL0006373 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.1626 ORF CAL0006376 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.1628 ORF LAP41 CAL0006379 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.1628 ORF LAP41 CAL0006379 PMID: 14663094|CGD_REF: CAL0080633 homozygous diploid, systematic mutation set (homozygous insertion mutants generated with URA3-ARG4-URA3 (UAU1) cassette) null BWP17 viable C. albicans orf19.1631 ORF ERG6 CAL0006397 PMID: 9593144|CGD_REF: CAL0081262 homozygous diploid, classical genetics null Not recorded small molecule transport: abnormal plasma membrane permeability is altered C. albicans orf19.1631 ORF ERG6 CAL0006397 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.1631 ORF ERG6 CAL0006397 PMID: 14507372|CGD_REF: CAL0088818 heterozygous diploid, large-scale survey (large-scale identification of essential genes by gene replacement and conditional expression (GRACE) method) repressible CAI-4 viable one allele is deleted and the other is placed under repressible Tet promoter C. albicans orf19.1631 ORF ERG6 CAL0006397 PMID: 9593144|CGD_REF: CAL0081262 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.1631 ORF ERG6 CAL0006397 PMID: 9593144|CGD_REF: CAL0081262 homozygous diploid, classical genetics null Not recorded chemical compound accumulation: abnormal sterol plasma membrane sterol content is altered C. albicans orf19.1631 ORF ERG6 CAL0006397 PMID: 9593144|CGD_REF: CAL0081262 homozygous diploid, classical genetics null Not recorded resistance to chemicals: increased nystatin C. albicans orf19.1631 ORF ERG6 CAL0006397 PMID: 11847103|CGD_REF: CAL0081043 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased cyclosporin A also displays hypersensitivity to FK506 C. albicans orf19.1631 ORF ERG6 CAL0006397 PMID: 11847103|CGD_REF: CAL0081043 heterozygous diploid, classical genetics null Not recorded resistance to chemicals: normal cyclosporin A also displays wild-type resistance to FK506 C. albicans orf19.1631 ORF ERG6 CAL0006397 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, competitive growth (haploinsufficient phenotype assay, barcode deletion set) null SC5314 resistance to chemicals: increased fluconazole C. albicans orf19.1631 ORF ERG6 CAL0006397 PMID: 24204207|CGD_REF: CAL0000173572 classical genetics null Other C. albicans resistance to chemicals: increased amphotericin B C. albicans orf19.1631 ORF ERG6 CAL0006397 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient YPD medium C. albicans orf19.1631 ORF ERG6 CAL0006397 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient YNB medium C. albicans orf19.1631 ORF ERG6 CAL0006397 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 invasive growth: decreased solid SLAD media C. albicans orf19.1631 ORF ERG6 CAL0006397 PMID: 21135205|CGD_REF: CAL0139967 heterozygous diploid, large-scale survey (large-scale identification of genes essential for virulence in mouse) repressible CAI-4 virulence: absent mouse intravenous infection C. albicans orf19.1633 ORF UTP4 CAL0006401 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.1633 ORF UTP4 CAL0006401 PMID: 21135205|CGD_REF: CAL0139967 heterozygous diploid, competitive growth (large-scale identification of genes essential for virulence in mouse) repressible CAI-4 virulence: decreased mouse intravenous infection C. albicans orf19.1634 ORF CAL0006403 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.1634 ORF CAL0006403 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.1634 ORF CAL0006403 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.1634 ORF CAL0006403 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.1635 ORF RPL12 CAL0006405 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.1637 ORF CAL0006410 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.1639 ORF CAL0006414 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.1641 ORF CAL0000012 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.1643 ORF CAL0000015 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.1643 ORF CAL0000015 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.1643 ORF CAL0000015 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.1643 ORF CAL0000015 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.1646 ORF CAL0000019 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.1648 ORF RAD50 CAL0000021 PMID: 17965250|CGD_REF: CAL0118884 homozygous diploid, classical genetics null Not recorded UV resistance: decreased C. albicans orf19.1648 ORF RAD50 CAL0000021 PMID: 17965250|CGD_REF: CAL0118884 homozygous diploid, classical genetics null Not recorded vegetative growth: decreased rate C. albicans orf19.1648 ORF RAD50 CAL0000021 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.1648 ORF RAD50 CAL0000021 PMID: 17965250|CGD_REF: CAL0118884 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.1648 ORF RAD50 CAL0000021 PMID: 17965250|CGD_REF: CAL0118884 homozygous diploid, classical genetics null Not recorded oxidative stress resistance: decreased hydrogen peroxide C. albicans orf19.1648 ORF RAD50 CAL0000021 PMID: 17965250|CGD_REF: CAL0118884 homozygous diploid, classical genetics null Not recorded chromosome segregation: abnormal increased chromosome instability C. albicans orf19.1648 ORF RAD50 CAL0000021 PMID: 17965250|CGD_REF: CAL0118884 homozygous diploid, classical genetics null Not recorded oxidative stress resistance: decreased tert-butyl hydroperoxide C. albicans orf19.1648 ORF RAD50 CAL0000021 PMID: 17965250|CGD_REF: CAL0118884 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased ethyl methanesulfonate C. albicans orf19.1648 ORF RAD50 CAL0000021 PMID: 17965250|CGD_REF: CAL0118884 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased methyl methanesulfonate C. albicans orf19.1648 ORF RAD50 CAL0000021 PMID: 17965250|CGD_REF: CAL0118884 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased camptothecin C. albicans orf19.1648 ORF RAD50 CAL0000021 PMID: 17965250|CGD_REF: CAL0118884 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased fluconazole C. albicans orf19.1649 ORF RNA1 CAL0000022 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.1653 ORF CAL0000036 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 invasive growth: decreased solid SLAD media C. albicans orf19.1654 ORF CAL0000038 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.1654 ORF CAL0000038 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.1654 ORF CAL0000038 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.1654 ORF CAL0000038 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.1655 ORF PXP2 CAL0000040 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.1656 ORF CAL0000041 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.1656 ORF CAL0000041 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.1656 ORF CAL0000041 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.1656 ORF CAL0000041 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.1659 ORF ALG8 CAL0000044 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.166 ORF ASG1 CAL0003189 PMID: 18451058|CGD_REF: CAL0118988 homozygous diploid, classical genetics null Not recorded respiratory growth: absent unable to utilize the nonfermentable carbon sources sodium acetate, acetic acid, ethanol, or sodium citrate C. albicans orf19.166 ORF ASG1 CAL0003189 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.166 ORF ASG1 CAL0003189 PMID: 18451058|CGD_REF: CAL0118988 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.166 ORF ASG1 CAL0003189 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.166 ORF ASG1 CAL0003189 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.166 ORF ASG1 CAL0003189 PMID: 22073120|CGD_REF: CAL0000143592 homozygous diploid, classical genetics null BWP17 hyphal growth: decreased C. albicans orf19.166 ORF ASG1 CAL0003189 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.166 ORF ASG1 CAL0003189 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.1661 ORF DBP5 CAL0000067 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.1663 ORF MNT2 CAL0000069 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.1663 ORF MNT2 CAL0000069 PMID: 14507372|CGD_REF: CAL0088818 heterozygous diploid, large-scale survey (large-scale identification of essential genes by gene replacement and conditional expression (GRACE) method) repressible CAI-4 viable one allele is deleted and the other is placed under repressible Tet promoter C. albicans orf19.1663 ORF MNT2 CAL0000069 PMID: 15519997|CGD_REF: CAL0082462 homozygous diploid, classical genetics null Not recorded adhesion: decreased adhesion to Matrigel or to human buccal epithelial cells C. albicans orf19.1663 ORF MNT2 CAL0000069 PMID: 18680523|CGD_REF: CAL0119367 homozygous diploid, classical genetics null Not recorded interaction with host/environment: abnormal decreased viability during growth in co-culture with Pseudomonas aeruginosa C. albicans orf19.1663 ORF MNT2 CAL0000069 PMID: 15519997|CGD_REF: CAL0082462 homozygous diploid, classical genetics null Not recorded virulence: normal mouse intravenous infection C. albicans orf19.1664 ORF CAL0000070 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.1665 ORF MNT1 CAL0000071 PMID: 9636208|CGD_REF: CAL0081546 homozygous diploid, classical genetics null Not recorded germ tube formation: normal serum- or GlcNAc-containing or Spider media C. albicans orf19.1665 ORF MNT1 CAL0000071 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.1665 ORF MNT1 CAL0000071 PMID: 9636208|CGD_REF: CAL0081546 heterozygous diploid, classical genetics null Not recorded viable wild-type growth rate C. albicans orf19.1665 ORF MNT1 CAL0000071 PMID: 9636208|CGD_REF: CAL0081546 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.1665 ORF MNT1 CAL0000071 PMID: 15519997|CGD_REF: CAL0082462 homozygous diploid, classical genetics null Not recorded adhesion: decreased adhesion to Matrigel or to human buccal epithelial cells C. albicans orf19.1665 ORF MNT1 CAL0000071 PMID: 9636208|CGD_REF: CAL0081546 homozygous diploid, classical genetics null Not recorded adhesion: decreased adhesion to human buccal epithelial cells C. albicans orf19.1665 ORF MNT1 CAL0000071 PMID: 18680523|CGD_REF: CAL0119367 homozygous diploid, classical genetics null Not recorded interaction with host/environment: abnormal decreased viability during growth in co-culture with Pseudomonas aeruginosa C. albicans orf19.1665 ORF MNT1 CAL0000071 PMID: 9636208|CGD_REF: CAL0081546 homozygous diploid, classical genetics null Not recorded chemical compound accumulation: abnormal mannan severely decreased cell wall O-linked oligosaccharide containing second or third mannose C. albicans orf19.1665 ORF MNT1 CAL0000071 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.1665 ORF MNT1 CAL0000071 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: abnormal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.1665 ORF MNT1 CAL0000071 PMID: 9636208|CGD_REF: CAL0081546 homozygous diploid, classical genetics null Not recorded virulence: decreased decreased tissue colonization guinea pig intravenous infection C. albicans orf19.1665 ORF MNT1 CAL0000071 PMID: 9636208|CGD_REF: CAL0081546 heterozygous diploid, classical genetics null Not recorded virulence: decreased guinea pig intravenous infection C. albicans orf19.1665 ORF MNT1 CAL0000071 PMID: 9636208|CGD_REF: CAL0081546 homozygous diploid, classical genetics null Not recorded virulence: decreased guinea pig intravenous infection C. albicans orf19.1665 ORF MNT1 CAL0000071 PMID: 9636208|CGD_REF: CAL0081546 homozygous diploid, classical genetics null Not recorded virulence: decreased exhibits slightly decreased tissue colonization mouse intravenous infection C. albicans orf19.1665 ORF MNT1 CAL0000071 PMID: 15519997|CGD_REF: CAL0082462 homozygous diploid, classical genetics null Not recorded virulence: normal mouse intravenous infection C. albicans orf19.1665 ORF MNT1 CAL0000071 PMID: 9636208|CGD_REF: CAL0081546 heterozygous diploid, classical genetics null Not recorded virulence: decreased mouse intravenous infection C. albicans orf19.1665 ORF MNT1 CAL0000071 PMID: 9636208|CGD_REF: CAL0081546 heterozygous diploid, classical genetics null Not recorded virulence: decreased rat vaginal infection C. albicans orf19.1665 ORF MNT1 CAL0000071 PMID: 9636208|CGD_REF: CAL0081546 homozygous diploid, classical genetics null Not recorded virulence: decreased rat vaginal infection C. albicans orf19.1665 ORF MNT1 CAL0000071 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.1665 ORF MNT1 CAL0000071 PMID: 24736223|CGD_REF: CAL0000173840 homozygous diploid, classical genetics null CAI-4 biofilm formation: decreased mixed species biofilms with Streptococcus gordonii C. albicans orf19.1665 ORF MNT1 CAL0000071 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.1667 ORF CAL0000073 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.1669 ORF AFG3 CAL0000075 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.1669 ORF AFG3 CAL0000075 PMID: 12524333|CGD_REF: CAL0080691 homozygous diploid, systematic mutation set (homozygous insertion mutants generated with URA3-ARG4-URA3 (UAU1) cassette) null BWP17 inviable homozygous null mutant strain could not be recovered, suggesting that the gene is essential under the selection conditions C. albicans orf19.1670 ORF BRO1 CAL0000103 PMID: 15371534|CGD_REF: CAL0082134 homozygous diploid, classical genetics null BWP17 hyphal growth: normal solid medium, alkaline pH C. albicans orf19.1670 ORF BRO1 CAL0000103 PMID: 15590834|CGD_REF: CAL0082485 homozygous diploid, classical genetics null Not recorded vacuolar transport: decreased defect in multivesicular body (MVB) transport to the vacuole C. albicans orf19.1670 ORF BRO1 CAL0000103 PMID: 15371534|CGD_REF: CAL0082134 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.1670 ORF BRO1 CAL0000103 PMID: 15590834|CGD_REF: CAL0082485 heterozygous diploid, classical genetics null Not recorded viable C. albicans orf19.1670 ORF BRO1 CAL0000103 PMID: 15590834|CGD_REF: CAL0082485 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.1670 ORF BRO1 CAL0000103 PMID: 15590834|CGD_REF: CAL0082485 homozygous diploid, classical genetics null BWP17 filamentous growth: normal solid M199 medium, pH 8, or liquid media with serum C. albicans orf19.1670 ORF BRO1 CAL0000103 PMID: 20581294|CGD_REF: CAL0125802 homozygous diploid, classical genetics null BWP17 metal resistance: decreased lithium chloride (150 mM) YPD plus 150 mM lithium chloride C. albicans orf19.1671 ORF UTR2 CAL0000104 PMID: 15042589|CGD_REF: CAL0080741 homozygous diploid, classical genetics null Not recorded resistance to chemicals: normal Calcofluor White C. albicans orf19.1671 ORF UTR2 CAL0000104 PMID: 15042589|CGD_REF: CAL0080741 heterozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased sodium dodecyl sulfate sensitivity is intermediate between that of the homozygous null mutant and wild type C. albicans orf19.1671 ORF UTR2 CAL0000104 PMID: 15042589|CGD_REF: CAL0080741 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased sodium dodecyl sulfate C. albicans orf19.1671 ORF UTR2 CAL0000104 PMID: 15042589|CGD_REF: CAL0080741 homozygous diploid, classical genetics null Not recorded viable wild-type growth rate C. albicans orf19.1671 ORF UTR2 CAL0000104 PMID: 17074760|CGD_REF: CAL0117089 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.1671 ORF UTR2 CAL0000104 PMID: 15042589|CGD_REF: CAL0080741 heterozygous diploid, classical genetics null Not recorded adhesion: decreased adhesion to human FaDu oropharyngeal epithelial cells C. albicans orf19.1671 ORF UTR2 CAL0000104 PMID: 15042589|CGD_REF: CAL0080741 homozygous diploid, classical genetics null Not recorded adhesion: decreased adhesion to human FaDu oropharyngeal epithelial cells C. albicans orf19.1671 ORF UTR2 CAL0000104 PMID: 15042589|CGD_REF: CAL0080741 homozygous diploid, classical genetics null BWP17 invasive growth: absent solid Spider medium C. albicans orf19.1671 ORF UTR2 CAL0000104 PMID: 15042589|CGD_REF: CAL0080741 homozygous diploid, classical genetics null Not recorded ionic stress resistance: normal sodium chloride C. albicans orf19.1671 ORF UTR2 CAL0000104 PMID: 15042589|CGD_REF: CAL0080741 homozygous diploid, classical genetics null Not recorded resistance to chemicals: normal amphotericin B C. albicans orf19.1671 ORF UTR2 CAL0000104 PMID: 15042589|CGD_REF: CAL0080741 homozygous diploid, classical genetics null Not recorded resistance to chemicals: normal micafungin C. albicans orf19.1671 ORF UTR2 CAL0000104 PMID: 17074760|CGD_REF: CAL0117089 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased Congo Red C. albicans orf19.1671 ORF UTR2 CAL0000104 PMID: 15042589|CGD_REF: CAL0080741 homozygous diploid, classical genetics null Not recorded resistance to chemicals: normal fluconazole C. albicans orf19.1671 ORF UTR2 CAL0000104 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: decreased growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.1671 ORF UTR2 CAL0000104 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: abnormal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.1671 ORF UTR2 CAL0000104 PMID: 15042589|CGD_REF: CAL0080741 homozygous diploid, classical genetics null Not recorded virulence: decreased exhibits decreased kidney and brain colonization mouse intravenous infection C. albicans orf19.1671 ORF UTR2 CAL0000104 PMID: 17074760|CGD_REF: CAL0117089 homozygous diploid, classical genetics null Not recorded virulence: decreased mouse intravenous infection C. albicans orf19.1671 ORF UTR2 CAL0000104 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.1671 ORF UTR2 CAL0000104 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.1672 ORF CAL0000105 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.1673 ORF PPT1 CAL0000106 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.1673 ORF PPT1 CAL0000106 PMID: 18708562|CGD_REF: CAL0119375 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.1673 ORF PPT1 CAL0000106 PMID: 18708562|CGD_REF: CAL0119375 homozygous diploid, classical genetics null Not recorded virulence: decreased insect infection C. albicans orf19.1674 ORF CDC53 CAL0000107 PMID: 19270112|CGD_REF: CAL0122496 heterozygous diploid, classical genetics repressible Not recorded viability: decreased decreased viability during growth C. albicans orf19.1674 ORF CDC53 CAL0000107 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.1674 ORF CDC53 CAL0000107 PMID: 19270112|CGD_REF: CAL0122496 heterozygous diploid, classical genetics repressible CAI-4 invasive growth: increased solid YPD C. albicans orf19.1674 ORF CDC53 CAL0000107 PMID: 19270112|CGD_REF: CAL0122496 heterozygous diploid, classical genetics repressible CAI-4 filamentous growth: increased increased filamentous growth under yeast growth conditions C. albicans orf19.1674 ORF CDC53 CAL0000107 PMID: 22080453|CGD_REF: CAL0000143626 heterozygous diploid, classical genetics conditional cdc53-R462C/cdc53::LEU2 (ts mutation analogous to S. cerevisiae cdc53-1) Other C. albicans heat sensitivity: increased restrictive temperature (37 deg) upon shift, cells stop dividing and produce germ tube-like extensions C. albicans orf19.1674 ORF CDC53 CAL0000107 PMID: 22080453|CGD_REF: CAL0000143626 heterozygous diploid, classical genetics conditional cdc53-R462C/cdc53::LEU2 (ts mutation analogous to S. cerevisiae cdc53-1) Other C. albicans cell shape: abnormal semipermissive temperature (30 deg) elongated cells C. albicans orf19.1675 ORF CAL0000108 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.1676 ORF CAL0000109 PMID: 23572557|CGD_REF: CAL0000158900 homozygous diploid, classical genetics null orf19.1676::Tn7-UAU1/orf19.1676::Tn7-URA3 BWP17 viable C. albicans orf19.1679 ORF CAL0000112 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient SLAD medium C. albicans orf19.1680 ORF TFP1 CAL0000146 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.1682 ORF CAL0000148 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.1683 ORF PPH21 CAL0000149 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.1683 ORF PPH21 CAL0000149 PMID: 18708562|CGD_REF: CAL0119375 heterozygous diploid, classical genetics null Not recorded viable C. albicans orf19.1685 ORF ZCF7 CAL0000151 PMID: 20041210|CGD_REF: CAL0124764 homozygous diploid, systematic mutation set null SN152 colony appearance: abnormal Spider medium at 37 deg C strongly decreased colony wrinkling and enhanced peripheral filamentation C. albicans orf19.1685 ORF ZCF7 CAL0000151 PMID: 22073120|CGD_REF: CAL0000143592 homozygous diploid, classical genetics null BWP17 viable C. albicans orf19.1685 ORF ZCF7 CAL0000151 PMID: 22073120|CGD_REF: CAL0000143592 homozygous diploid, classical genetics null BWP17 colony appearance: abnormal decreased colony wrinkling C. albicans orf19.1685 ORF ZCF7 CAL0000151 PMID: 22073120|CGD_REF: CAL0000143592 homozygous diploid, classical genetics null BWP17 hyphal growth: decreased C. albicans orf19.1686 ORF CAL0000152 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.1687 ORF CAL0000153 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.169 ORF CHO2 CAL0003197 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.1690 ORF TOS1 CAL0000187 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.1690 ORF TOS1 CAL0000187 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.1690 ORF TOS1 CAL0000187 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.1690 ORF TOS1 CAL0000187 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient YPD medium C. albicans orf19.1690 ORF TOS1 CAL0000187 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient YNB medium C. albicans orf19.1690 ORF TOS1 CAL0000187 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient SLAD medium C. albicans orf19.1690 ORF TOS1 CAL0000187 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.1691 ORF CAL0000188 PMID: 21414038|CGD_REF: CAL0141808 homozygous diploid, classical genetics null BWP17 viable C. albicans orf19.1691 ORF CAL0000188 PMID: 21414038|CGD_REF: CAL0141808 homozygous diploid, classical genetics null BWP17 biofilm formation: normal C. albicans orf19.1693 ORF CAS4 CAL0000189 PMID: 18843050|CGD_REF: CAL0120345 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased Calcofluor White C. albicans orf19.1693 ORF CAS4 CAL0000189 PMID: 17555439|CGD_REF: CAL0117968 homozygous diploid, classical genetics null Not recorded survival rate in stationary phase: decreased C. albicans orf19.1693 ORF CAS4 CAL0000189 PMID: 18843050|CGD_REF: CAL0120345 heterozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased itraconazole sensitivity is intermediate between that of the homozygous null mutant and wild type C. albicans orf19.1693 ORF CAS4 CAL0000189 PMID: 18843050|CGD_REF: CAL0120345 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased itraconazole C. albicans orf19.1693 ORF CAS4 CAL0000189 PMID: 18843050|CGD_REF: CAL0120345 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased sodium dodecyl sulfate C. albicans orf19.1693 ORF CAS4 CAL0000189 PMID: 18843050|CGD_REF: CAL0120345 homozygous diploid, classical genetics null CAI-4 hyphal growth: decreased solid and liquid media C. albicans orf19.1693 ORF CAS4 CAL0000189 PMID: 18843050|CGD_REF: CAL0120345 homozygous diploid, classical genetics null Not recorded vegetative growth: decreased rate C. albicans orf19.1693 ORF CAS4 CAL0000189 PMID: 15964282|CGD_REF: CAL0114274 homozygous diploid, systematic mutation set (split-marker transposon insertion strategy to disrupt both alleles) null BWP17 viable C. albicans orf19.1693 ORF CAS4 CAL0000189 PMID: 16552442|CGD_REF: CAL0115731 heterozygous diploid, classical genetics reduction of function Not recorded viable insertion mutation near 3' end C. albicans orf19.1693 ORF CAS4 CAL0000189 PMID: 18843050|CGD_REF: CAL0120345 heterozygous diploid, classical genetics null Not recorded viable URA3-blaster technique C. albicans orf19.1693 ORF CAS4 CAL0000189 PMID: 18843050|CGD_REF: CAL0120345 homozygous diploid, classical genetics null Not recorded viable URA3-blaster technique C. albicans orf19.1693 ORF CAS4 CAL0000189 PMID: 15964282|CGD_REF: CAL0114274 homozygous diploid, systematic mutation set (split-marker transposon insertion strategy to disrupt both alleles) null BWP17 biofilm formation: normal C. albicans orf19.1693 ORF CAS4 CAL0000189 PMID: 18843050|CGD_REF: CAL0120345 homozygous diploid, classical genetics null Not recorded cell cycle progression: abnormal cells are multinucleate C. albicans orf19.1693 ORF CAS4 CAL0000189 PMID: 18843050|CGD_REF: CAL0120345 homozygous diploid, classical genetics null Not recorded cell shape: abnormal cells are round and enlarged C. albicans orf19.1693 ORF CAS4 CAL0000189 PMID: 18843050|CGD_REF: CAL0120345 homozygous diploid, classical genetics null Not recorded hypoosmotic stress resistance: decreased cells lyse in liquid YPD C. albicans orf19.1693 ORF CAS4 CAL0000189 PMID: 16552442|CGD_REF: CAL0115731 homozygous diploid, classical genetics null Not recorded inviable homozygous null mutant strain could not be recovered, suggesting that the gene is essential under the selection conditions; deletion or insertion mutations at codons 836, 842, 1163, or 1828 appear to be lethal C. albicans orf19.1693 ORF CAS4 CAL0000189 PMID: 18843050|CGD_REF: CAL0120345 homozygous diploid, classical genetics null Not recorded cell size: increased cells are round, large, and heterogeneous in size C. albicans orf19.1693 ORF CAS4 CAL0000189 PMID: 18843050|CGD_REF: CAL0120345 homozygous diploid, classical genetics null Not recorded cytokinesis: absent C. albicans orf19.1693 ORF CAS4 CAL0000189 PMID: 18843050|CGD_REF: CAL0120345 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased Hygromycin B C. albicans orf19.1693 ORF CAS4 CAL0000189 PMID: 16552442|CGD_REF: CAL0115731 heterozygous diploid, classical genetics reduction of function Not recorded resistance to chemicals: decreased caspofungin insertion mutation near 3' end C. albicans orf19.1693 ORF CAS4 CAL0000189 PMID: 18843050|CGD_REF: CAL0120345 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased Congo Red C. albicans orf19.1693 ORF CAS4 CAL0000189 PMID: 18843050|CGD_REF: CAL0120345 heterozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased fluconazole sensitivity is intermediate between that of the homozygous null mutant and wild type C. albicans orf19.1693 ORF CAS4 CAL0000189 PMID: 18843050|CGD_REF: CAL0120345 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased fluconazole C. albicans orf19.1693 ORF CAS4 CAL0000189 PMID: 22589718|CGD_REF: CAL0000157315 homozygous diploid, classical genetics null BWP17 biofilm formation: decreased C. albicans orf19.1698 ORF CAL0000192 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.1699 ORF BZZ1 CAL0000193 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.1699 ORF BZZ1 CAL0000193 PMID: 17431925|CGD_REF: CAL0117929 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.1699 ORF BZZ1 CAL0000193 PMID: 17431925|CGD_REF: CAL0117929 homozygous diploid, classical genetics null Not recorded cellular morphology: normal no defects in polarized growth detected C. albicans orf19.1701 ORF RKI1 CAL0000757 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.1702 ORF ARF3 CAL0000758 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.1702 ORF ARF3 CAL0000758 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: abnormal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.1702 ORF ARF3 CAL0000758 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.1702 ORF ARF3 CAL0000758 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.1704 ORF FOX3 CAL0000760 PMID: 23758791|CGD_REF: CAL0000172382 homozygous diploid, classical genetics null SC5314 viable C. albicans orf19.1704 ORF FOX3 CAL0000760 PMID: 23758791|CGD_REF: CAL0000172382 homozygous diploid, classical genetics null SC5314 utilization of carbon source: decreased fatty acid C. albicans orf19.1704 ORF FOX3 CAL0000760 PMID: 23758791|CGD_REF: CAL0000172382 homozygous diploid, classical genetics null SC5314 virulence: normal other model (chicken embryo) C. albicans orf19.1709 ORF CAL0000769 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.171 ORF DBP2 CAL0003204 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.1710 ORF ALI1 CAL0000774 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.1710 ORF ALI1 CAL0000774 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: decreased rate liquid synthetic complete medium C. albicans orf19.1710 ORF ALI1 CAL0000774 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.1710 ORF ALI1 CAL0000774 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.1711 ORF END3 CAL0000775 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.1714 ORF PGA44 CAL0000779 PMID: 17873081|CGD_REF: CAL0118685 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.1715 ORF IRO1 CAL0000781 PMID: 16237272|CGD_REF: CAL0114858 homozygous diploid, classical genetics null Not recorded vegetative growth: decreased rate C. albicans orf19.1715 ORF IRO1 CAL0000781 PMID: 16237272|CGD_REF: CAL0114858 heterozygous diploid, classical genetics null Not recorded viable C. albicans orf19.1715 ORF IRO1 CAL0000781 PMID: 16237272|CGD_REF: CAL0114858 heterozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased iron chelators heterozygous null mutant is sensitive to iron chelation but homozygous null mutant is not C. albicans orf19.1715 ORF IRO1 CAL0000781 PMID: 16237272|CGD_REF: CAL0114858 homozygous diploid, classical genetics null Not recorded virulence: decreased mouse intravenous infection C. albicans orf19.1715 ORF IRO1 CAL0000781 PMID: 16237272|CGD_REF: CAL0114858 heterozygous diploid, classical genetics null Not recorded virulence: normal mouse intravenous infection C. albicans orf19.1715 ORF IRO1 CAL0000781 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient YPD medium C. albicans orf19.1715 ORF IRO1 CAL0000781 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient SC medium C. albicans orf19.1715 ORF IRO1 CAL0000781 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient SLAD medium C. albicans orf19.1716 ORF URA3 CAL0000783 PMID: 14500538|CGD_REF: CAL0081606 heterozygous diploid, classical genetics repressible CAI-4 hyphal growth: decreased solid M199 or Spider media strains carrying URA3 expressed from an ectopic location C. albicans orf19.1716 ORF URA3 CAL0000783 PMID: 15502413|CGD_REF: CAL0082471 homozygous diploid, classical genetics null Not recorded viable accumulates abundant orotic acid (visible as crystals in growth media) in the presence of acetate C. albicans orf19.1716 ORF URA3 CAL0000783 PMID: 14500538|CGD_REF: CAL0081606 heterozygous diploid, classical genetics misexpression Not recorded adhesion: decreased adhesion to human buccal epithelial cells strain carries URA3 expressed from an ectopic location C. albicans orf19.1716 ORF URA3 CAL0000783 PMID: 1936958|CGD_REF: CAL0081320 homozygous diploid, classical genetics null Not recorded auxotrophy uridine C. albicans orf19.1716 ORF URA3 CAL0000783 PMID: 15817775|CGD_REF: CAL0104045 heterozygous diploid, classical genetics misexpression CAI-4 filamentous growth: abnormal defect had originally been attributed to mutation of HWP1 C. albicans orf19.1716 ORF URA3 CAL0000783 PMID: 1569024|CGD_REF: CAL0082007 unknown ploidy, classical genetics unspecified WO-1 phenotypic switching: normal white-to-opaque switching C. albicans orf19.1716 ORF URA3 CAL0000783 PMID: 9784536|CGD_REF: CAL0082010 unknown ploidy, classical genetics misexpression CAI-4 virulence: abnormal variable expression due to the use of the ura-blaster gene disruption technique affects virulence in the mouse intravenous infection model mouse intravenous infection C. albicans orf19.1716 ORF URA3 CAL0000783 PMID: 8349105|CGD_REF: CAL0082009 homozygous diploid, classical genetics null SC5314 auxotrophy uridine C. albicans orf19.1716 ORF URA3 CAL0000783 PMID: 8349105|CGD_REF: CAL0082009 heterozygous diploid, classical genetics null CAF2-1 viable C. albicans orf19.1716 ORF URA3 CAL0000783 PMID: 11731143|CGD_REF: CAL0082012 homozygous diploid, classical genetics null CAI-4 adhesion: abnormal adhesion to Matrigel or human buccal epithelial cells C. albicans orf19.1716 ORF URA3 CAL0000783 PMID: 11731143|CGD_REF: CAL0082012 heterozygous diploid, classical genetics null CAF2-1 adhesion: normal adhesion to Matrigel or human buccal epithelial cells C. albicans orf19.1716 ORF URA3 CAL0000783 PMID: 11371541|CGD_REF: CAL0081877 homozygous diploid, classical genetics null WO-1 auxotrophy uridine also resistant to 5-fluoroorotic acid (5-FOA) C. albicans orf19.1716 ORF URA3 CAL0000783 PMID: 11371541|CGD_REF: CAL0081877 homozygous diploid, classical genetics null WO-1 viable C. albicans orf19.1716 ORF URA3 CAL0000783 PMID: 3031459|CGD_REF: CAL0080670 homozygous diploid, classical genetics null Other C. albicans auxotrophy uridine also 5-FOA resistant C. albicans orf19.1716 ORF URA3 CAL0000783 PMID: 3031459|CGD_REF: CAL0080670 heterozygous diploid, classical genetics null Other C. albicans viable C. albicans orf19.1716 ORF URA3 CAL0000783 PMID: 3031459|CGD_REF: CAL0080670 homozygous diploid, classical genetics null Other C. albicans viable C. albicans orf19.1716 ORF URA3 CAL0000783 PMID: 15817775|CGD_REF: CAL0104045 heterozygous diploid, classical genetics misexpression CAI-4 virulence: decreased defect had originally been attributed to mutation of HWP1 mouse intravenous infection C. albicans orf19.1716 ORF URA3 CAL0000783 PMID: 10865906|CGD_REF: CAL0081191 homozygous diploid, classical genetics null CAI-4 virulence: abnormal reconstituted human intestinal epithelium, Caco-2 cells abolished migration across cell monolayer in absence of exogenous uridine ex vivo model of infection C. albicans orf19.1716 ORF URA3 CAL0000783 PMID: 1879944|CGD_REF: CAL0091438 homozygous diploid, classical genetics null Not recorded virulence: decreased immunosuppressed mouse intravenous infection C. albicans orf19.1716 ORF URA3 CAL0000783 PMID: 14500538|CGD_REF: CAL0081606 heterozygous diploid, classical genetics misexpression Not recorded virulence: decreased strain carries URA3 expressed from an ectopic location mouse intravenous infection C. albicans orf19.1716 ORF URA3 CAL0000783 PMID: 16835826|CGD_REF: CAL0116678 homozygous diploid, classical genetics null Not recorded virulence: decreased rat peritoneal infection C. albicans orf19.1718 ORF ZCF8 CAL0000786 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.1718 ORF ZCF8 CAL0000786 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.1718 ORF ZCF8 CAL0000786 PMID: 22073120|CGD_REF: CAL0000143592 homozygous diploid, classical genetics null BWP17 viable C. albicans orf19.1718 ORF ZCF8 CAL0000786 PMID: 22073120|CGD_REF: CAL0000143592 homozygous diploid, classical genetics null BWP17 colony appearance: abnormal increased colony wrinkling C. albicans orf19.1718 ORF ZCF8 CAL0000786 PMID: 22359502|CGD_REF: CAL0000144048 homozygous diploid, classical genetics null BWP17 viable insertion mutant, independent BWP17 and SN152 deletion mutants also tested C. albicans orf19.1718 ORF ZCF8 CAL0000786 PMID: 22359502|CGD_REF: CAL0000144048 homozygous diploid, classical genetics null BWP17 adhesion: decreased insertion mutant, independent BWP17 and SN152 deletion mutants also tested C. albicans orf19.1718 ORF ZCF8 CAL0000786 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.1718 ORF ZCF8 CAL0000786 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.172 ORF RPC19 CAL0003206 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.1720 ORF CAL0000801 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.1721 ORF NCE103 CAL0000802 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.1721 ORF NCE103 CAL0000802 PMID: 16303561|CGD_REF: CAL0115037 homozygous diploid, classical genetics null Not recorded inviable viability is rescued by concentrations of CO2 greater than 0.5% C. albicans orf19.1721 ORF NCE103 CAL0000802 PMID: 19200725|CGD_REF: CAL0122386 homozygous diploid, classical genetics null Not recorded phenotypic switching: decreased 1% CO2 white-to-opaque switching C. albicans orf19.1723 ORF CAL0000804 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.1723 ORF CAL0000804 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient YPD medium C. albicans orf19.1723 ORF CAL0000804 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient SC medium C. albicans orf19.1723 ORF CAL0000804 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient SLAD medium C. albicans orf19.1725 ORF CAL0000807 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.1725 ORF CAL0000807 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.1725 ORF CAL0000807 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.1725 ORF CAL0000807 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.1727 ORF PMC1 CAL0000810 PMID: 12753189|CGD_REF: CAL0080803 homozygous diploid, classical genetics null Not recorded resistance to chemicals: increased lithium chloride C. albicans orf19.1727 ORF PMC1 CAL0000810 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.1727 ORF PMC1 CAL0000810 PMID: 12753189|CGD_REF: CAL0080803 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.1727 ORF PMC1 CAL0000810 PMID: 12753189|CGD_REF: CAL0080803 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased calcium dichloride C. albicans orf19.1727 ORF PMC1 CAL0000810 PMID: 12753189|CGD_REF: CAL0080803 homozygous diploid, classical genetics null Not recorded resistance to chemicals: increased fluconazole C. albicans orf19.1729 ORF CAL0000814 PMID: 15964282|CGD_REF: CAL0114274 homozygous diploid, systematic mutation set (split-marker transposon insertion strategy to disrupt both alleles) null BWP17 viable C. albicans orf19.1729 ORF CAL0000814 PMID: 15964282|CGD_REF: CAL0114274 homozygous diploid, systematic mutation set (split-marker transposon insertion strategy to disrupt both alleles) null BWP17 biofilm formation: normal C. albicans orf19.173 ORF CAL0003208 PMID: 17555439|CGD_REF: CAL0117968 homozygous diploid, classical genetics null Not recorded survival rate in stationary phase: decreased C. albicans orf19.173 ORF CAL0003208 PMID: 20041210|CGD_REF: CAL0124764 homozygous diploid, systematic mutation set null SN152 resistance to chemicals: increased flucytosine strongly resistant C. albicans orf19.173 ORF CAL0003208 PMID: 15964282|CGD_REF: CAL0114274 homozygous diploid, systematic mutation set (split-marker transposon insertion strategy to disrupt both alleles) null BWP17 viable C. albicans orf19.173 ORF CAL0003208 PMID: 19463063|CGD_REF: CAL0123630 homozygous diploid, systematic mutation set (split-marker transposon insertion strategy to disrupt both alleles) null BWP17 viable C. albicans orf19.173 ORF CAL0003208 PMID: 15964282|CGD_REF: CAL0114274 homozygous diploid, systematic mutation set (split-marker transposon insertion strategy to disrupt both alleles) null BWP17 biofilm formation: normal C. albicans orf19.173 ORF CAL0003208 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.173 ORF CAL0003208 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.173 ORF CAL0003208 PMID: 19463063|CGD_REF: CAL0123630 homozygous diploid, systematic mutation set (split-marker transposon insertion strategy to disrupt both alleles) null BWP17 virulence: normal Toll mutant D. melanogaster invasive infection insect infection C. albicans orf19.173 ORF CAL0003208 PMID: 19463063|CGD_REF: CAL0123630 homozygous diploid, classical genetics null BWP17 virulence: normal BALB/c mice mouse intravenous infection C. albicans orf19.173 ORF CAL0003208 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.173 ORF CAL0003208 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.1734 ORF CAL0000831 PMID: 19115836|CGD_REF: CAL0122036 heterozygous diploid, competitive growth (haploinsufficient phenotype assay, barcode deletion set) null SC5314 resistance to chemicals: decreased virgineone C. albicans orf19.1736 ORF CAL0000835 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 invasive growth: decreased solid SLAD media C. albicans orf19.1738 ORF UGP1 CAL0000839 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.1738 ORF UGP1 CAL0000839 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient YPD medium C. albicans orf19.1738 ORF UGP1 CAL0000839 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient SC medium C. albicans orf19.1738 ORF UGP1 CAL0000839 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient YNB medium C. albicans orf19.1738 ORF UGP1 CAL0000839 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient SLAD medium C. albicans orf19.1741 ORF DIT1 CAL0000853 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.1742 ORF HEM3 CAL0000854 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.1742 ORF HEM3 CAL0000854 PMID: 2671651|CGD_REF: CAL0081367 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.1742 ORF HEM3 CAL0000854 PMID: 14507372|CGD_REF: CAL0088818 heterozygous diploid, large-scale survey (large-scale identification of essential genes by gene replacement and conditional expression (GRACE) method) repressible CAI-4 inviable one allele is deleted and the other is placed under repressible Tet promoter C. albicans orf19.1742 ORF HEM3 CAL0000854 PMID: 1879944|CGD_REF: CAL0091438 homozygous diploid, classical genetics null Not recorded auxotrophy heme C. albicans orf19.1742 ORF HEM3 CAL0000854 PMID: 2671651|CGD_REF: CAL0081367 homozygous diploid, classical genetics null Not recorded auxotrophy heme C. albicans orf19.1742 ORF HEM3 CAL0000854 PMID: 1879944|CGD_REF: CAL0091438 homozygous diploid, classical genetics null Not recorded virulence: decreased mouse intravenous infection C. albicans orf19.1743 ORF ACS1 CAL0000855 PMID: 18689527|CGD_REF: CAL0119372 homozygous diploid, classical genetics null Not recorded utilization of carbon source: normal C. albicans orf19.1743 ORF ACS1 CAL0000855 PMID: 18689527|CGD_REF: CAL0119372 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.1743 ORF ACS1 CAL0000855 PMID: 18689527|CGD_REF: CAL0119372 homozygous diploid, classical genetics null Not recorded virulence: normal mouse intravenous infection C. albicans orf19.1746 ORF CAL0000858 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 invasive growth: decreased solid SLAD media C. albicans orf19.1747 ORF KIP2 CAL0000859 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.1747 ORF KIP2 CAL0000859 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.1747 ORF KIP2 CAL0000859 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: abnormal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.1747 ORF KIP2 CAL0000859 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: decreased rate liquid synthetic complete medium C. albicans orf19.1747 ORF KIP2 CAL0000859 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.1750 ORF SLR1 CAL0000867 PMID: 23381995|CGD_REF: CAL0000158490 homozygous diploid, classical genetics null BWP17 viable C. albicans orf19.1750 ORF SLR1 CAL0000867 PMID: 23381995|CGD_REF: CAL0000158490 homozygous diploid, classical genetics null BWP17 cold sensitivity: increased 16 deg C. albicans orf19.1750 ORF SLR1 CAL0000867 PMID: 23381995|CGD_REF: CAL0000158490 homozygous diploid, classical genetics null BWP17 resistance to chemicals: decreased sodium dodecyl sulfate C. albicans orf19.1750 ORF SLR1 CAL0000867 PMID: 23381995|CGD_REF: CAL0000158490 homozygous diploid, classical genetics null BWP17 resistance to chemicals: decreased Calcofluor White C. albicans orf19.1750 ORF SLR1 CAL0000867 PMID: 23381995|CGD_REF: CAL0000158490 homozygous diploid, classical genetics null BWP17 filamentous growth: decreased solid Spider medium, solid or liquid RPMI 1640 medium C. albicans orf19.1750 ORF SLR1 CAL0000867 PMID: 23381995|CGD_REF: CAL0000158490 homozygous diploid, classical genetics null BWP17 virulence: decreased in vitro model of infection (FaDu oral epithelial cell line) C. albicans orf19.1750 ORF SLR1 CAL0000867 PMID: 23381995|CGD_REF: CAL0000158490 homozygous diploid, classical genetics null BWP17 resistance to phagocytosis: decreased in vitro model of infection (endocytosis by human umbilical vein endothelial cells and human brain microvascular endothelial cells) C. albicans orf19.1750 ORF SLR1 CAL0000867 PMID: 23381995|CGD_REF: CAL0000158490 homozygous diploid, classical genetics null BWP17 virulence: decreased mouse oropharyngeal infection C. albicans orf19.1750 ORF SLR1 CAL0000867 PMID: 23381995|CGD_REF: CAL0000158490 homozygous diploid, classical genetics null BWP17 virulence: decreased mouse intravenous infection C. albicans orf19.1751 ORF SPT23 CAL0000868 PMID: 16415349|CGD_REF: CAL0115693 heterozygous diploid, classical genetics repressible Not recorded auxotrophy unsaturated fatty acid C. albicans orf19.1753 ORF PUS7 CAL0000869 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.1754 ORF CMK2 CAL0000870 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.1754 ORF CMK2 CAL0000870 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.1754 ORF CMK2 CAL0000870 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.1754 ORF CMK2 CAL0000870 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.1754 ORF CMK2 CAL0000870 PMID: 24661877|CGD_REF: CAL0000173817 homozygous diploid, classical genetics null BWP17 viable C. albicans orf19.1754 ORF CMK2 CAL0000870 PMID: 24661877|CGD_REF: CAL0000173817 homozygous diploid, classical genetics null BWP17 resistance to chemicals: decreased Calcofluor White C. albicans orf19.1754 ORF CMK2 CAL0000870 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.1755 ORF SET2 CAL0000871 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.1755 ORF SET2 CAL0000871 PMID: 19555456|CGD_REF: CAL0123821 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.1756 ORF GPD1 CAL0000872 PMID: 23572557|CGD_REF: CAL0000158900 homozygous diploid, classical genetics null BWP17 adhesion: decreased Fluxion Bioflux 200, equipped with a microscope, was used for adherence analysis allowing a constant flow of cells through microfluidic channels C. albicans orf19.1756 ORF GPD1 CAL0000872 PMID: 23572557|CGD_REF: CAL0000158900 homozygous diploid, classical genetics null BWP17 resistance to chemicals: increased fluconazole RPMI+MOPS+Histidine medium , 6 hours without shaking at 37 degrees C 24 hr fluconazole treatment in 96 well plates C. albicans orf19.1757 ORF CAL0000873 PMID: 15964282|CGD_REF: CAL0114274 homozygous diploid, systematic mutation set (split-marker transposon insertion strategy to disrupt both alleles) null BWP17 viable C. albicans orf19.1757 ORF CAL0000873 PMID: 15964282|CGD_REF: CAL0114274 homozygous diploid, systematic mutation set (split-marker transposon insertion strategy to disrupt both alleles) null BWP17 biofilm formation: normal C. albicans orf19.1759 ORF PHO23 CAL0000874 PMID: 14663094|CGD_REF: CAL0080633 homozygous diploid, systematic mutation set (homozygous insertion mutants generated with URA3-ARG4-URA3 (UAU1) cassette) null BWP17 viable C. albicans orf19.1759 ORF PHO23 CAL0000874 PMID: 17880264|CGD_REF: CAL0118619 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.1759 ORF PHO23 CAL0000874 PMID: 17880264|CGD_REF: CAL0118619 homozygous diploid, classical genetics null Not recorded phenotypic switching: increased MTLa/MTLa background white-to-opaque switching; slight increase C. albicans orf19.176 ORF OPT4 CAL0003217 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.176 ORF OPT4 CAL0003217 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.176 ORF OPT4 CAL0003217 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.176 ORF OPT4 CAL0003217 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.1760 ORF RAS1 CAL0000896 PMID: 19788542|CGD_REF: CAL0124303 homozygous diploid, classical genetics null Not recorded metal resistance: decreased cobalt(2+) C. albicans orf19.1760 ORF RAS1 CAL0000896 PMID: 15269278|CGD_REF: CAL0082117 homozygous diploid, classical genetics null Not recorded thermotolerance: increased slightly increased resistance to heat shock C. albicans orf19.1760 ORF RAS1 CAL0000896 PMID: 10515923|CGD_REF: CAL0081766 homozygous diploid, classical genetics overexpression CAI-4 heat sensitivity: increased C. albicans orf19.1760 ORF RAS1 CAL0000896 PMID: 11722734|CGD_REF: CAL0081767 homozygous diploid, classical genetics null Not recorded hyphal growth: absent all hyphal inducing conditions except microaerophilic conditions forms short pseudohyphae C. albicans orf19.1760 ORF RAS1 CAL0000896 PMID: 11722734|CGD_REF: CAL0081767 homozygous diploid, classical genetics activation Not recorded hyphal growth: increased hyperfilamentation is suppressed by mutation of HST7, CPH1, EFG1, CDC35, or CPH1 and EFG1 C. albicans orf19.1760 ORF RAS1 CAL0000896 PMID: 10515923|CGD_REF: CAL0081766 homozygous diploid, classical genetics overexpression CAI-4 hyphal growth: increased solid media C. albicans orf19.1760 ORF RAS1 CAL0000896 PMID: 11722734|CGD_REF: CAL0081767 heterozygous diploid, classical genetics null Not recorded hyphal growth: normal liquid media C. albicans orf19.1760 ORF RAS1 CAL0000896 PMID: 11722734|CGD_REF: CAL0081767 homozygous diploid, classical genetics null Not recorded hyphal growth: normal microaerophilic conditions C. albicans orf19.1760 ORF RAS1 CAL0000896 PMID: 11722734|CGD_REF: CAL0081767 heterozygous diploid, classical genetics null Not recorded hyphal growth: decreased solid media C. albicans orf19.1760 ORF RAS1 CAL0000896 PMID: 11722734|CGD_REF: CAL0081767 homozygous diploid, classical genetics null Not recorded hyphal growth: absent within murine macrophages C. albicans orf19.1760 ORF RAS1 CAL0000896 PMID: 11722734|CGD_REF: CAL0081767 homozygous diploid, classical genetics null Not recorded vegetative growth: decreased rate growth defect is rescued by cAMP C. albicans orf19.1760 ORF RAS1 CAL0000896 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.1760 ORF RAS1 CAL0000896 PMID: 10515923|CGD_REF: CAL0081766 heterozygous diploid, classical genetics null CAI-4 viable C. albicans orf19.1760 ORF RAS1 CAL0000896 PMID: 10515923|CGD_REF: CAL0081766 homozygous diploid, classical genetics null CAI-4 viable C. albicans orf19.1760 ORF RAS1 CAL0000896 PMID: 10515923|CGD_REF: CAL0081766 homozygous diploid, classical genetics overexpression CAI-4 viable C. albicans orf19.1760 ORF RAS1 CAL0000896 PMID: 11722734|CGD_REF: CAL0081767 heterozygous diploid, classical genetics null Not recorded viable C. albicans orf19.1760 ORF RAS1 CAL0000896 PMID: 11722734|CGD_REF: CAL0081767 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.1760 ORF RAS1 CAL0000896 PMID: 16407097|CGD_REF: CAL0115390 homozygous diploid, classical genetics null Not recorded apoptosis: decreased increased resistance to apoptosis-inducing stimuli C. albicans orf19.1760 ORF RAS1 CAL0000896 PMID: 16407097|CGD_REF: CAL0115390 heterozygous diploid, classical genetics activation RAS1(Val13) Not recorded apoptosis: increased mutant is hypersensitive to apoptosis-inducing stimuli C. albicans orf19.1760 ORF RAS1 CAL0000896 PMID: 16407097|CGD_REF: CAL0115390 heterozygous diploid, classical genetics activation RAS1(Val13) Not recorded viable C. albicans orf19.1760 ORF RAS1 CAL0000896 PMID: 10515923|CGD_REF: CAL0081766 heterozygous diploid, classical genetics null RAS1/ras1::hisG CAI-4 hyphal growth: normal solid or liquid media normal hyphal induction by serum C. albicans orf19.1760 ORF RAS1 CAL0000896 PMID: 10515923|CGD_REF: CAL0081766 heterozygous diploid, classical genetics dominant negative RAS1/RAS1-A16 CAI-4 chemical compound accumulation: normal glycogen C. albicans orf19.1760 ORF RAS1 CAL0000896 PMID: 10515923|CGD_REF: CAL0081766 heterozygous diploid, classical genetics dominant negative RAS1/RAS1-A16 CAI-4 heat sensitivity: normal C. albicans orf19.1760 ORF RAS1 CAL0000896 PMID: 10515923|CGD_REF: CAL0081766 heterozygous diploid, classical genetics dominant negative RAS1/RAS1-A16 CAI-4 hyphal growth: absent solid media C. albicans orf19.1760 ORF RAS1 CAL0000896 PMID: 10515923|CGD_REF: CAL0081766 heterozygous diploid, classical genetics dominant negative RAS1/RAS1-A16 CAI-4 viable C. albicans orf19.1760 ORF RAS1 CAL0000896 PMID: 10515923|CGD_REF: CAL0081766 heterozygous diploid, classical genetics activation RAS1/RAS1-V13 CAI-4 chemical compound accumulation: decreased glycogen C. albicans orf19.1760 ORF RAS1 CAL0000896 PMID: 10515923|CGD_REF: CAL0081766 heterozygous diploid, classical genetics activation RAS1/RAS1-V13 CAI-4 hyphal growth: increased solid media C. albicans orf19.1760 ORF RAS1 CAL0000896 PMID: 10515923|CGD_REF: CAL0081766 heterozygous diploid, classical genetics activation RAS1/RAS1-V13 CAI-4 viable C. albicans orf19.1760 ORF RAS1 CAL0000896 PMID: 10515923|CGD_REF: CAL0081766 homozygous diploid, classical genetics null ras1::hisG/ras1::hph CAI-4 chemical compound accumulation: normal glycogen C. albicans orf19.1760 ORF RAS1 CAL0000896 PMID: 10515923|CGD_REF: CAL0081766 homozygous diploid, classical genetics null ras1::hisG/ras1::hph CAI-4 germ tube formation: absent serum-containing solid or liquid media C. albicans orf19.1760 ORF RAS1 CAL0000896 PMID: 10515923|CGD_REF: CAL0081766 homozygous diploid, classical genetics null ras1::hisG/ras1::hph CAI-4 vegetative growth: decreased rate C. albicans orf19.1760 ORF RAS1 CAL0000896 PMID: 19788542|CGD_REF: CAL0124303 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased hydrogen peroxide C. albicans orf19.1760 ORF RAS1 CAL0000896 PMID: 19759180|CGD_REF: CAL0124252 homozygous diploid, classical genetics null Not recorded oxidative stress resistance: decreased hydrogen peroxide C. albicans orf19.1760 ORF RAS1 CAL0000896 PMID: 19200725|CGD_REF: CAL0122386 homozygous diploid, classical genetics null Not recorded phenotypic switching: decreased air or 1% CO2 white-to-opaque switching C. albicans orf19.1760 ORF RAS1 CAL0000896 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.1760 ORF RAS1 CAL0000896 PMID: 21407800|CGD_REF: CAL0141800 homozygous diploid, classical genetics null BWP17 interaction with host/environment: abnormal significantly reduces adhesion, invasion, and damage to epithelial cells ex vivo model of infection C. albicans orf19.1760 ORF RAS1 CAL0000896 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.1760 ORF RAS1 CAL0000896 PMID: 12379711|CGD_REF: CAL0081037 homozygous diploid, classical genetics null CAI-4 resistance to killing by host cells: decreased in vitro model of infection (RAW 264.7 mouse macrophages) C. albicans orf19.1760 ORF RAS1 CAL0000896 PMID: 21908593|CGD_REF: CAL0000142934 aneuploid, classical genetics reduction of function Ras1-C288S Other C. albicans hyphal growth: absent C. albicans orf19.1760 ORF RAS1 CAL0000896 PMID: 21908593|CGD_REF: CAL0000142934 aneuploid, classical genetics reduction of function Ras1-C287S Other C. albicans hyphal growth: abnormal delayed hyphal induction C. albicans orf19.1760 ORF RAS1 CAL0000896 PMID: 11722734|CGD_REF: CAL0081767 homozygous diploid, classical genetics null Not recorded virulence: decreased murine macrophage culture decreased capacity to damage cells in vitro model of infection C. albicans orf19.1760 ORF RAS1 CAL0000896 PMID: 12381467|CGD_REF: CAL0087147 homozygous diploid, classical genetics null Not recorded virulence: decreased Galleria mellonella (Greater Wax Moth) larvae insect infection C. albicans orf19.1760 ORF RAS1 CAL0000896 PMID: 11722734|CGD_REF: CAL0081767 homozygous diploid, classical genetics null Not recorded virulence: decreased virulence defect is suppressed by Hst7p overproduction mouse intravenous infection C. albicans orf19.1760 ORF RAS1 CAL0000896 PMID: 11722734|CGD_REF: CAL0081767 heterozygous diploid, classical genetics null Not recorded virulence: normal mouse intravenous infection C. albicans orf19.1760 ORF RAS1 CAL0000896 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.1760 ORF RAS1 CAL0000896 PMID: 22923045|CGD_REF: CAL0000157829 homozygous diploid, classical genetics null Other C. albicans formation of anatomical structure: absent elevated concentrations of CO2 at 37 deg finger structure C. albicans orf19.1760 ORF RAS1 CAL0000896 PMID: 20118211|CGD_REF: CAL0125028 homozygous diploid, classical genetics null CAI-4 oxidative stress resistance: decreased decreased H2O2 resistance C. albicans orf19.1760 ORF RAS1 CAL0000896 PMID: 20118211|CGD_REF: CAL0125028 homozygous diploid, classical genetics null CAI-4 oxidative stress resistance: decreased decreased H2O2 resistance C. albicans orf19.1760 ORF RAS1 CAL0000896 PMID: 20300604|CGD_REF: CAL0125136 heterozygous diploid, classical genetics repressible MET3p::RAS1V13 (constitutively active allele under MET promoter) WO-1 phenotypic switching: decreased GlcNAc medium -met -cys (repressing conditions) C. albicans orf19.1760 ORF RAS1 CAL0000896 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.1761 ORF CAL0000897 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.1762 ORF OCA1 CAL0000898 PMID: 14663094|CGD_REF: CAL0080633 homozygous diploid, systematic mutation set (homozygous insertion mutants generated with URA3-ARG4-URA3 (UAU1) cassette) null BWP17 viable C. albicans orf19.1762 ORF OCA1 CAL0000898 PMID: 18708562|CGD_REF: CAL0119375 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.1762 ORF OCA1 CAL0000898 PMID: 18708562|CGD_REF: CAL0119375 homozygous diploid, classical genetics null Not recorded virulence: decreased insect infection C. albicans orf19.1769 ORF CAL0000905 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.1771 ORF CWC22 CAL0000928 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.1773 ORF RAP1 CAL0000930 PMID: 14745778|CGD_REF: CAL0081219 heterozygous diploid, classical genetics repressible Not recorded flocculation: increased cell aggregation at stationary phase C. albicans orf19.1773 ORF RAP1 CAL0000930 PMID: 12706897|CGD_REF: CAL0081765 homozygous diploid, classical genetics null CAI-4 hyphal growth: decreased liquid RPMI plus serum slight decrease C. albicans orf19.1773 ORF RAP1 CAL0000930 PMID: 12706897|CGD_REF: CAL0081765 homozygous diploid, classical genetics null CAI-4 hyphal growth: normal various liquid and solid media C. albicans orf19.1773 ORF RAP1 CAL0000930 PMID: 12706897|CGD_REF: CAL0081765 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.1773 ORF RAP1 CAL0000930 PMID: 20008550|CGD_REF: CAL0124742 homozygous diploid, classical genetics null rap1::hisG-URA3-hisG BWP17 viable C. albicans orf19.1773 ORF RAP1 CAL0000930 PMID: 20008550|CGD_REF: CAL0124742 homozygous diploid, classical genetics null rap1::hisG-URA3-hisG BWP17 vegetative growth: decreased rate C. albicans orf19.1773 ORF RAP1 CAL0000930 PMID: 20008550|CGD_REF: CAL0124742 homozygous diploid, classical genetics null rap1::hisG-URA3-hisG BWP17 colony size: decreased C. albicans orf19.1773 ORF RAP1 CAL0000930 PMID: 20008550|CGD_REF: CAL0124742 homozygous diploid, classical genetics null rap1::hisG-URA3-hisG BWP17 filamentous growth: increased increased frequency of filamentous cells in rich medium C. albicans orf19.1773 ORF RAP1 CAL0000930 PMID: 20008550|CGD_REF: CAL0124742 homozygous diploid, classical genetics null rap1::hisG-URA3-hisG BWP17 telomere length: increased extremely long and heterogeneous telomeres (more than 20 kb and less than 1 kb) C. albicans orf19.1773 ORF RAP1 CAL0000930 PMID: 12706897|CGD_REF: CAL0081765 homozygous diploid, classical genetics null CAI-4 pseudohyphal growth: increased C. albicans orf19.1774 ORF CAL0000931 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.1776 ORF CAL0000933 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.1777 ORF CAL0000934 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.1779 ORF MP65 CAL0000936 PMID: 17217426|CGD_REF: CAL0117711 homozygous diploid, classical genetics null CAI-4 hyphal growth: decreased severe defect C. albicans orf19.1779 ORF MP65 CAL0000936 PMID: 17217426|CGD_REF: CAL0117711 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.1779 ORF MP65 CAL0000936 PMID: 17217426|CGD_REF: CAL0117711 homozygous diploid, classical genetics null Not recorded adhesion: decreased adhesion to plastic C. albicans orf19.1779 ORF MP65 CAL0000936 PMID: 21414038|CGD_REF: CAL0141808 homozygous diploid, classical genetics null BWP17 viable C. albicans orf19.1779 ORF MP65 CAL0000936 PMID: 21575184|CGD_REF: CAL0142021 homozygous diploid, classical genetics null MP65::hisG/MP65::hisG CAI-4 protein/peptide modification: increased phosphorylated Mkc1p indicates activation of the cell wall integrity pathway in the mutant Mkc1p C. albicans orf19.1779 ORF MP65 CAL0000936 PMID: 21575184|CGD_REF: CAL0142021 homozygous diploid, classical genetics null MP65::hisG/MP65::hisG CAI-4 protein/peptide modification: increased phosphorylated Cek1p indicates activation of the cell wall integrity pathway in the mutant Cek11p C. albicans orf19.1779 ORF MP65 CAL0000936 PMID: 21575184|CGD_REF: CAL0142021 homozygous diploid, classical genetics null MP65::hisG/MP65::hisG CAI-4 resistance to chemicals: decreased Congo Red induces morphological changes such as swelling, clumping and formation of hyphae C. albicans orf19.1779 ORF MP65 CAL0000936 PMID: 21575184|CGD_REF: CAL0142021 homozygous diploid, classical genetics null MP65::hisG/MP65::hisG CAI-4 RNA accumulation: increased expression increaseS in the absence of stressing agents DDR48 mRNA C. albicans orf19.1779 ORF MP65 CAL0000936 PMID: 21575184|CGD_REF: CAL0142021 homozygous diploid, classical genetics null MP65::hisG/MP65::hisG CAI-4 RNA accumulation: increased expression increases in the absence of stressing agents SOD5 mRNA C. albicans orf19.1779 ORF MP65 CAL0000936 PMID: 21575184|CGD_REF: CAL0142021 homozygous diploid, classical genetics null MP65::hisG/MP65::hisG CAI-4 RNA accumulation: increased expression increases in the absence of stressing agents DDR48 mRNA C. albicans orf19.1779 ORF MP65 CAL0000936 PMID: 21575184|CGD_REF: CAL0142021 homozygous diploid, classical genetics null MP65::hisG/MP65::hisG CAI-4 adhesion: decreased reduction in adhesion to buccal epithelial cells and Caco-2 cell monolayers DDR48 mRNA C. albicans orf19.1779 ORF MP65 CAL0000936 PMID: 21575184|CGD_REF: CAL0142021 homozygous diploid, classical genetics null MP65::hisG/MP65::hisG CAI-4 biofilm formation: decreased C. albicans orf19.1779 ORF MP65 CAL0000936 PMID: 17217426|CGD_REF: CAL0117711 homozygous diploid, classical genetics null Not recorded virulence: decreased mouse intravenous infection C. albicans orf19.1783 ORF YOR1 CAL0000963 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 invasive growth: decreased solid SLAD media C. albicans orf19.1789.1 ORF LYS1 CAL0006591 PMID: 16292576|CGD_REF: CAL0115364 heterozygous diploid, classical genetics reduction of function Not recorded protein activity: abnormal site-directed mutagenesis study, defining residues involved in catalysis of saccharopine dehydrogenase (forward) reaction and reverse reaction Lys1p C. albicans orf19.1789.1 ORF LYS1 CAL0006591 PMID: 1429460|CGD_REF: CAL0081490 unknown ploidy, classical genetics unspecified Other C. albicans viable C. albicans orf19.1789.1 ORF LYS1 CAL0006591 PMID: 1429460|CGD_REF: CAL0081490 unknown ploidy, classical genetics unspecified Other C. albicans auxotrophy L-lysine C. albicans orf19.1789.1 ORF LYS1 CAL0006591 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 invasive growth: decreased solid SLAD media C. albicans orf19.1791 ORF CAL0000994 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.1792 ORF CAL0000995 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.1793 ORF CAL0000996 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.1793 ORF CAL0000996 PMID: 14663094|CGD_REF: CAL0080633 homozygous diploid, systematic mutation set (homozygous insertion mutants generated with URA3-ARG4-URA3 (UAU1) cassette) null BWP17 viable C. albicans orf19.1795 ORF PUF3 CAL0000998 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.1795 ORF PUF3 CAL0000998 PMID: 14663094|CGD_REF: CAL0080633 homozygous diploid, systematic mutation set (homozygous insertion mutants generated with URA3-ARG4-URA3 (UAU1) cassette) null BWP17 viable C. albicans orf19.1797 ORF CAL0001000 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.1797 ORF CAL0001000 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.1797 ORF CAL0001000 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.1797 ORF CAL0001000 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.1797 ORF CAL0001000 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.1798 ORF TSC2 CAL0001001 PMID: 14663094|CGD_REF: CAL0080633 homozygous diploid, systematic mutation set (homozygous insertion mutants generated with URA3-ARG4-URA3 (UAU1) cassette) null BWP17 viable C. albicans orf19.1798 ORF TSC2 CAL0001001 PMID: 19095072|CGD_REF: CAL0122066 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.1798 ORF TSC2 CAL0001001 PMID: 19095072|CGD_REF: CAL0122066 homozygous diploid, classical genetics null SC5314 filamentous growth: decreased low nitrogen conditions C. albicans orf19.1799 ORF GAP5 CAL0001002 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.18 ORF IMH3 CAL0000509 PMID: 15665003|CGD_REF: CAL0082188 unknown ploidy, classical genetics unspecified imh3-A251T CAI-4 resistance to chemicals: decreased mizoribine monophosphate C. albicans orf19.18 ORF IMH3 CAL0000509 PMID: 15665003|CGD_REF: CAL0082188 heterozygous diploid, classical genetics null CAI-4 viable C. albicans orf19.18 ORF IMH3 CAL0000509 PMID: 15665003|CGD_REF: CAL0082188 unknown ploidy, classical genetics unspecified imh3-A251T CAI-4 resistance to chemicals: increased mycophenolic acid C. albicans orf19.18 ORF IMH3 CAL0000509 PMID: 15665003|CGD_REF: CAL0082188 heterozygous diploid, classical genetics null CAI-4 resistance to chemicals: decreased mizoribine C. albicans orf19.18 ORF IMH3 CAL0000509 PMID: 11119495|CGD_REF: CAL0080774 heterozygous diploid, classical genetics gain of function IMH3(r) (I47V, S102A, G482D mutations) Other C. albicans resistance to chemicals: increased mycophenolic acid C. albicans orf19.18 ORF IMH3 CAL0000509 PMID: 15034753|CGD_REF: CAL0081253 heterozygous diploid, classical genetics overexpression Other C. albicans resistance to chemicals: increased mycophenolic acid C. albicans orf19.18 ORF IMH3 CAL0000509 PMID: 15034753|CGD_REF: CAL0081253 aneuploid, classical genetics overexpression CAI-4 viable C. albicans orf19.18 ORF IMH3 CAL0000509 PMID: 9079920|CGD_REF: CAL0081442 aneuploid, classical genetics overexpression CAI-4 resistance to chemicals: increased mycophenolic acid C. albicans orf19.18 ORF IMH3 CAL0000509 PMID: 20571955|CGD_REF: CAL0125847 heterozygous diploid, classical genetics overexpression SC5314 filamentous growth: decreased C. albicans orf19.1800 ORF CAL0001572 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.1800 ORF CAL0001572 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 invasive growth: decreased solid SLAD media C. albicans orf19.1801 ORF CBR1 CAL0001574 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.1802 ORF OFD1 CAL0001575 PMID: 24237696|CGD_REF: CAL0000173698 homozygous diploid, classical genetics null BWP17 viable C. albicans orf19.1802 ORF OFD1 CAL0001575 PMID: 24237696|CGD_REF: CAL0000173698 homozygous diploid, classical genetics null BWP17 filamentous growth: increased C. albicans orf19.1802 ORF OFD1 CAL0001575 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient YPD medium C. albicans orf19.1802 ORF OFD1 CAL0001575 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient SC medium C. albicans orf19.1802 ORF OFD1 CAL0001575 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient SLAD medium C. albicans orf19.1803 ORF CDC43 CAL0001576 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.1803 ORF CDC43 CAL0001576 PMID: 14507372|CGD_REF: CAL0088818 heterozygous diploid, large-scale survey (large-scale identification of essential genes by gene replacement and conditional expression (GRACE) method) repressible CAI-4 viable one allele is deleted and the other is placed under repressible Tet promoter C. albicans orf19.1803 ORF CDC43 CAL0001576 PMID: 10633104|CGD_REF: CAL0080870 homozygous diploid, classical genetics null cdc43::hisG/cdc43::URA3 CAI-4 cellular morphology: abnormal round, swollen and clumped cells with significantly fewer buds C. albicans orf19.1803 ORF CDC43 CAL0001576 PMID: 10633104|CGD_REF: CAL0080870 homozygous diploid, classical genetics null cdc43::hisG/cdc43::URA3 CAI-4 vegetative growth: decreased rate C. albicans orf19.1803 ORF CDC43 CAL0001576 PMID: 10633104|CGD_REF: CAL0080870 homozygous diploid, classical genetics null cdc43::hisG/cdc43::URA3 CAI-4 viable growth at late log phase reduced to 70% of wild type C. albicans orf19.1804 ORF CAL0001578 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.1804 ORF CAL0001578 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 invasive growth: decreased solid SLAD media C. albicans orf19.1805 ORF PEX14 CAL0001580 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.1805 ORF PEX14 CAL0001580 PMID: 14663094|CGD_REF: CAL0080633 homozygous diploid, systematic mutation set (homozygous insertion mutants generated with URA3-ARG4-URA3 (UAU1) cassette) null BWP17 viable C. albicans orf19.1805 ORF PEX14 CAL0001580 PMID: 23856128|CGD_REF: CAL0000172540 homozygous diploid, classical genetics null BWP17 resistance to chemicals: decreased propolis C. albicans orf19.1808 ORF MED5 CAL0001584 PMID: 23873866|CGD_REF: CAL0000172574 homozygous diploid, classical genetics null SN152 phenotypic switching: abnormal C. albicans orf19.1814 ORF STT4 CAL0001601 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.1814 ORF STT4 CAL0001601 PMID: 22891265|CGD_REF: CAL0000157680 heterozygous diploid, classical genetics repressible stt4/pTetSTT4 BWP17 viable repressive conditions, doxycycline C. albicans orf19.1814 ORF STT4 CAL0001601 PMID: 22891265|CGD_REF: CAL0000157680 heterozygous diploid, classical genetics repressible stt4/pTetSTT4 BWP17 invasive growth: decreased C. albicans orf19.1814 ORF STT4 CAL0001601 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.1814 ORF STT4 CAL0001601 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: abnormal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.1814 ORF STT4 CAL0001601 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.1814 ORF STT4 CAL0001601 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.1815 ORF CAL0001603 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.1816 ORF ALS3 CAL0001605 PMID: 15256583|CGD_REF: CAL0082078 homozygous diploid, classical genetics null Not recorded germ tube formation: normal RPMI or Lee's media C. albicans orf19.1816 ORF ALS3 CAL0001605 PMID: 19023418|CGD_REF: CAL0121072 homozygous diploid, classical genetics null Not recorded utilization of iron source: decreased ferritin C. albicans orf19.1816 ORF ALS3 CAL0001605 PMID: 19427882|CGD_REF: CAL0123547 heterozygous diploid, classical genetics repressible Not recorded adhesion: decreased adhesion to vascular endothelial cells and buccal epithelial cells antibody binding blocks adhesion C. albicans orf19.1816 ORF ALS3 CAL0001605 PMID: 15758214|CGD_REF: CAL0082338 heterozygous diploid, classical genetics null Not recorded adhesion: decreased adhesion to pharyngeal epithelial cells or human umbilical vein endothelial cells effect is allele-specific: mutant with only the large ALS3 allele shows wild-type adhesion and mutant with only the small ALS3 allele shows an adhesion defect C. albicans orf19.1816 ORF ALS3 CAL0001605 PMID: 15256583|CGD_REF: CAL0082078 homozygous diploid, classical genetics null Not recorded adhesion: decreased adhesion to human buccal epithelial cells and umbilical vein endothelial cells C. albicans orf19.1816 ORF ALS3 CAL0001605 PMID: 15758214|CGD_REF: CAL0082338 homozygous diploid, classical genetics null Not recorded adhesion: decreased adhesion to pharyngeal epithelial cells or human umbilical vein endothelial cells C. albicans orf19.1816 ORF ALS3 CAL0001605 PMID: 17311474|CGD_REF: CAL0117976 homozygous diploid, classical genetics null Not recorded adhesion: decreased adhesion to human umbilical vein endothelial cells C. albicans orf19.1816 ORF ALS3 CAL0001605 PMID: 21407800|CGD_REF: CAL0141800 homozygous diploid, classical genetics null BWP17 interaction with host/environment: abnormal significantly reduces adhesion, invasion, and damage to epithelial cells ex vivo model of infection C. albicans orf19.1816 ORF ALS3 CAL0001605 PMID: 21436220|CGD_REF: CAL0141826 haploid, classical genetics null als3::SAT SC5314 biofilm formation: decreased defective in biofilm formation on an elastomer surface in vitro C. albicans orf19.1816 ORF ALS3 CAL0001605 PMID: 21436220|CGD_REF: CAL0141826 haploid, classical genetics null als3::SAT SC5314 virulence: normal mouse intravenous infection (6-8 wk old female BALB/c mice) C. albicans orf19.1816 ORF ALS3 CAL0001605 PMID: 22918893|CGD_REF: CAL0000157689 homozygous diploid, classical genetics null CAI-4 adhesion: decreased adhesion force between single cells of C. albicans and Staphylococcus aureus was reduced for a C. albicans als1 mutant strain, by atomic force and confocal microscopy C. albicans orf19.1816 ORF ALS3 CAL0001605 PMID: 22918893|CGD_REF: CAL0000157689 homozygous diploid, classical genetics null CAI-4 adhesion: decreased adhesion force between single cells of C. albicans and Staphylococcus aureus was reduced for a C. albicans als3 mutant strain, by atomic force and confocal microscopy C. albicans orf19.1816 ORF ALS3 CAL0001605 PMID: 22428031|CGD_REF: CAL0000156989 homozygous diploid, classical genetics null SC5314 adhesion: decreased reduced adhesion and damage to oral epithelial cells C. albicans orf19.1816 ORF ALS3 CAL0001605 PMID: 18683080|CGD_REF: CAL0119365 homozygous diploid, classical genetics null SC5314 biofilm formation: abnormal CDC reactor system decreased filamentation in early biofilm formation, but wild-type at later stages of biofilm growth C. albicans orf19.1816 ORF ALS3 CAL0001605 PMID: 16849795|CGD_REF: CAL0116362 homozygous diploid, classical genetics null CAI-4 biofilm formation: abnormal on silicone elastomer surfaces disorganized and weakened biofilm structure C. albicans orf19.1816 ORF ALS3 CAL0001605 PMID: 15256583|CGD_REF: CAL0082078 homozygous diploid, classical genetics null Not recorded virulence: decreased reconstituted human buccal epithelium ex vivo model of infection C. albicans orf19.1816 ORF ALS3 CAL0001605 PMID: 19023418|CGD_REF: CAL0121072 homozygous diploid, classical genetics null Not recorded virulence: decreased oral epithelial cells decreased capacity to damage cells in vitro model of infection C. albicans orf19.1816 ORF ALS3 CAL0001605 PMID: 16839200|CGD_REF: CAL0116292 homozygous diploid, classical genetics null als3::ARG4/als3::HIS1 BWP17 biofilm formation: abnormal Spider medium, 37 deg C for 60 h at 150-rpm agitation mutant displays a severe defect in biofilm formation; forms a rudimentary biofilm of 20 um in depth comprised mainly of yeast cells, with few hyphae C. albicans orf19.1816 ORF ALS3 CAL0001605 PMID: 20805332|CGD_REF: CAL0126199 homozygous diploid, classical genetics null CAI-4 biofilm formation: decreased C. albicans orf19.1816 ORF ALS3 CAL0001605 PMID: 21221944|CGD_REF: CAL0141180 homozygous diploid, classical genetics null als3::HIS1 BWP17 adhesion: decreased C. albicans orf19.1822 ORF UME6 CAL0001625 PMID: 19116272|CGD_REF: CAL0122035 heterozygous diploid, classical genetics overexpression CAI-8 hyphal growth: abnormal complete transition to hyphal growth in the absence of hyphae-inducing conditions C. albicans orf19.1822 ORF UME6 CAL0001625 PMID: 19054126|CGD_REF: CAL0121259 homozygous diploid, classical genetics null SN87 hyphal growth: decreased various media C. albicans orf19.1822 ORF UME6 CAL0001625 PMID: 18216277|CGD_REF: CAL0118892 heterozygous diploid, classical genetics null Not recorded viable C. albicans orf19.1822 ORF UME6 CAL0001625 PMID: 18216277|CGD_REF: CAL0118892 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.1822 ORF UME6 CAL0001625 PMID: 15964282|CGD_REF: CAL0114274 homozygous diploid, systematic mutation set (split-marker transposon insertion strategy to disrupt both alleles) null BWP17 inviable homozygous null mutant strain could not be recovered, suggesting that the gene is essential under the selection conditions C. albicans orf19.1822 ORF UME6 CAL0001625 PMID: 18216277|CGD_REF: CAL0118892 heterozygous diploid, classical genetics null CAF2-1 filamentous growth: abnormal filamentation defect is less severe than that of homozygous null mutant C. albicans orf19.1822 ORF UME6 CAL0001625 PMID: 18216277|CGD_REF: CAL0118892 homozygous diploid, classical genetics null CAF2-1 filamentous growth: abnormal Spider, Lee's, neutral pH, or serum media, or in mouse kidney filaments are short C. albicans orf19.1822 ORF UME6 CAL0001625 PMID: 22276126|CGD_REF: CAL0000143926 aneuploid, classical genetics overexpression Other C. albicans filamentous growth: increased C. albicans orf19.1822 ORF UME6 CAL0001625 PMID: 18216277|CGD_REF: CAL0118892 homozygous diploid, classical genetics null Not recorded virulence: decreased mouse intravenous infection C. albicans orf19.1822 ORF UME6 CAL0001625 PMID: 18216277|CGD_REF: CAL0118892 heterozygous diploid, classical genetics null Not recorded virulence: normal mouse intravenous infection C. albicans orf19.1822 ORF UME6 CAL0001625 PMID: 19116272|CGD_REF: CAL0122035 heterozygous diploid, classical genetics overexpression Not recorded virulence: increased mouse intravenous infection C. albicans orf19.1822 ORF UME6 CAL0001625 PMID: 19054126|CGD_REF: CAL0121259 homozygous diploid, classical genetics null Not recorded virulence: decreased mouse peritoneal infection C. albicans orf19.1822 ORF UME6 CAL0001625 PMID: 20360962|CGD_REF: CAL0125164 heterozygous diploid, classical genetics overexpression Other C. albicans biofilm formation: abnormal biofilm is more filamentous than normal and releases fewer yeast-form cells C. albicans orf19.1824 ORF PGA50 CAL0001627 PMID: 18765290|CGD_REF: CAL0119430 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.1825 ORF CAL0001629 PMID: 14663094|CGD_REF: CAL0080633 homozygous diploid, systematic mutation set (homozygous insertion mutants generated with URA3-ARG4-URA3 (UAU1) cassette) null BWP17 viable C. albicans orf19.1825 ORF CAL0001629 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.1825 ORF CAL0001629 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.1825 ORF CAL0001629 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.1825 ORF CAL0001629 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.1826 ORF MDM34 CAL0001630 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.1826 ORF MDM34 CAL0001630 PMID: 15964282|CGD_REF: CAL0114274 homozygous diploid, systematic mutation set (split-marker transposon insertion strategy to disrupt both alleles) null BWP17 viable C. albicans orf19.1826 ORF MDM34 CAL0001630 PMID: 15964282|CGD_REF: CAL0114274 homozygous diploid, systematic mutation set (split-marker transposon insertion strategy to disrupt both alleles) null BWP17 biofilm formation: normal C. albicans orf19.1828 ORF BUD16 CAL0001634 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.183 ORF HIS3 CAL0003242 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.1830 ORF CAL0001649 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 invasive growth: decreased solid SLAD media C. albicans orf19.1832 ORF FCY23 CAL0001652 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.1833 ORF CAL0001653 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.1836 ORF APN2 CAL0001657 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.1837 ORF TBP1 CAL0001658 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.1839 ORF RPA190 CAL0001661 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.1842 ORF BUD5 CAL0001675 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 invasive growth: decreased solid SLAD media C. albicans orf19.1844 ORF CAL0001677 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.1844 ORF CAL0001677 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 invasive growth: decreased solid SLAD media C. albicans orf19.1847 ORF ARO10 CAL0001679 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.1850 ORF SIW14 CAL0001689 PMID: 18708562|CGD_REF: CAL0119375 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.1850 ORF SIW14 CAL0001689 PMID: 18708562|CGD_REF: CAL0119375 homozygous diploid, classical genetics null Not recorded virulence: decreased insect infection C. albicans orf19.1853 ORF HHT2 CAL0001692 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.1853 ORF HHT2 CAL0001692 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 invasive growth: decreased solid SLAD media C. albicans orf19.1854 ORF HHF22 CAL0001693 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.1854 ORF HHF22 CAL0001693 PMID: 20498713|CGD_REF: CAL0125627 homozygous diploid, classical genetics null BWP17 viable C. albicans orf19.1857 ORF CAL0001696 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.1857 ORF CAL0001696 PMID: 14663094|CGD_REF: CAL0080633 homozygous diploid, systematic mutation set (homozygous insertion mutants generated with URA3-ARG4-URA3 (UAU1) cassette) null BWP17 viable C. albicans orf19.1860 ORF LSC2 CAL0001726 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.1860 ORF LSC2 CAL0001726 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.1860 ORF LSC2 CAL0001726 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.1860 ORF LSC2 CAL0001726 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.1865 ORF MCS7 CAL0001732 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.1867 ORF CAL0001734 PMID: 23417561|CGD_REF: CAL0000158590 homozygous diploid, classical genetics null SC5314 viable C. albicans orf19.1871 ORF CAL0001763 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.1872 ORF CAL0001764 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 invasive growth: decreased solid SLAD media C. albicans orf19.1876 ORF CAL0001768 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.1878 ORF MED4 CAL0001770 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.188 ORF CAL0003257 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.1880 ORF HEM15 CAL0001790 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.1881 ORF LPT1 CAL0001792 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.1881 ORF LPT1 CAL0001792 PMID: 24406902|CGD_REF: CAL0000173753 homozygous diploid, classical genetics null SN152 viable C. albicans orf19.1883 ORF YCS4 CAL0001793 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.1885 ORF TAF4 CAL0001794 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.1885 ORF TAF4 CAL0001794 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, competitive growth (haploinsufficient phenotype assay, barcode deletion set) null SC5314 resistance to chemicals: decreased ergosterol analogs (ECC69 and/or ECC1384) C. albicans orf19.1886 ORF RCL1 CAL0001795 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.1886 ORF RCL1 CAL0001795 PMID: 16607011|CGD_REF: CAL0115846 heterozygous diploid, classical genetics null SC5314 viable C. albicans orf19.1886 ORF RCL1 CAL0001795 PMID: 16607011|CGD_REF: CAL0115846 homozygous diploid, classical genetics null SC5314 inviable homozygous null mutant strain could not be recovered, suggesting that the gene is essential under the selection conditions C. albicans orf19.1886 ORF RCL1 CAL0001795 PMID: 16607011|CGD_REF: CAL0115846 heterozygous diploid, classical genetics repressible SC5314 inviable C. albicans orf19.1887 ORF CAL0001796 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.1888 ORF CAL0001797 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.1890 ORF CAL0001823 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.1891 ORF APR1 CAL0001825 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.1893 ORF CAL0001827 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient YNB medium C. albicans orf19.1893 ORF CAL0001827 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 invasive growth: decreased solid SLAD media C. albicans orf19.1896 ORF SSC1 CAL0001828 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.1900 ORF CAL0002493 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.1901 ORF MCM3 CAL0002494 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.1902 ORF NOC4 CAL0002495 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, competitive growth (haploinsufficient phenotype assay, barcode deletion set) null SC5314 resistance to chemicals: increased 5-fluorouracil C. albicans orf19.1902 ORF NOC4 CAL0002495 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, competitive growth (haploinsufficient phenotype assay, barcode deletion set) null SC5314 resistance to chemicals: increased tubercidin C. albicans orf19.1902 ORF NOC4 CAL0002495 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, competitive growth (haploinsufficient phenotype assay, barcode deletion set) null SC5314 resistance to chemicals: increased flucytosine C. albicans orf19.1902 ORF NOC4 CAL0002495 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.1907 ORF EMC9 CAL0002503 PMID: 14663094|CGD_REF: CAL0080633 homozygous diploid, systematic mutation set (homozygous insertion mutants generated with URA3-ARG4-URA3 (UAU1) cassette) null BWP17 viable C. albicans orf19.1907 ORF EMC9 CAL0002503 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.1907 ORF EMC9 CAL0002503 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.1907 ORF EMC9 CAL0002503 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: decreased rate liquid synthetic complete medium C. albicans orf19.1907 ORF EMC9 CAL0002503 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.191 ORF KIC1 CAL0003268 PMID: 18843050|CGD_REF: CAL0120345 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased Calcofluor White C. albicans orf19.191 ORF KIC1 CAL0003268 PMID: 18843050|CGD_REF: CAL0120345 heterozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased itraconazole sensitivity is intermediate between that of the homozygous null mutant and wild type C. albicans orf19.191 ORF KIC1 CAL0003268 PMID: 18843050|CGD_REF: CAL0120345 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased itraconazole C. albicans orf19.191 ORF KIC1 CAL0003268 PMID: 18843050|CGD_REF: CAL0120345 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased sodium dodecyl sulfate C. albicans orf19.191 ORF KIC1 CAL0003268 PMID: 18843050|CGD_REF: CAL0120345 homozygous diploid, classical genetics null CAI-4 hyphal growth: decreased solid and liquid media C. albicans orf19.191 ORF KIC1 CAL0003268 PMID: 18843050|CGD_REF: CAL0120345 homozygous diploid, classical genetics null Not recorded vegetative growth: decreased rate C. albicans orf19.191 ORF KIC1 CAL0003268 PMID: 18843050|CGD_REF: CAL0120345 heterozygous diploid, classical genetics null Not recorded viable URA3-blaster technique C. albicans orf19.191 ORF KIC1 CAL0003268 PMID: 18843050|CGD_REF: CAL0120345 homozygous diploid, classical genetics null Not recorded viable URA3-blaster technique C. albicans orf19.191 ORF KIC1 CAL0003268 PMID: 18843050|CGD_REF: CAL0120345 homozygous diploid, classical genetics null Not recorded cell cycle progression: abnormal cells are multinucleate C. albicans orf19.191 ORF KIC1 CAL0003268 PMID: 18843050|CGD_REF: CAL0120345 homozygous diploid, classical genetics null Not recorded cell shape: abnormal cells are round and enlarged C. albicans orf19.191 ORF KIC1 CAL0003268 PMID: 18843050|CGD_REF: CAL0120345 homozygous diploid, classical genetics null Not recorded hypoosmotic stress resistance: decreased cells lyse in liquid YPD C. albicans orf19.191 ORF KIC1 CAL0003268 PMID: 18843050|CGD_REF: CAL0120345 homozygous diploid, classical genetics null Not recorded cell size: increased cells are round, large, and heterogeneous in size C. albicans orf19.191 ORF KIC1 CAL0003268 PMID: 18843050|CGD_REF: CAL0120345 homozygous diploid, classical genetics null Not recorded cytokinesis: absent C. albicans orf19.191 ORF KIC1 CAL0003268 PMID: 18843050|CGD_REF: CAL0120345 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased Hygromycin B C. albicans orf19.191 ORF KIC1 CAL0003268 PMID: 18843050|CGD_REF: CAL0120345 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased Congo Red C. albicans orf19.191 ORF KIC1 CAL0003268 PMID: 18843050|CGD_REF: CAL0120345 heterozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased fluconazole sensitivity is intermediate between that of the homozygous null mutant and wild type C. albicans orf19.191 ORF KIC1 CAL0003268 PMID: 18843050|CGD_REF: CAL0120345 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased fluconazole C. albicans orf19.191 ORF KIC1 CAL0003268 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: increased growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.191 ORF KIC1 CAL0003268 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: abnormal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.191 ORF KIC1 CAL0003268 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, classical genetics null SN152 germ tube formation: decreased serum-containing medium C. albicans orf19.191 ORF KIC1 CAL0003268 PMID: 22589718|CGD_REF: CAL0000157315 homozygous diploid, classical genetics null BWP17 biofilm formation: decreased C. albicans orf19.191 ORF KIC1 CAL0003268 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: decreased rate liquid synthetic complete medium C. albicans orf19.191 ORF KIC1 CAL0003268 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.1911 ORF PGA52 CAL0002515 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.1911 ORF PGA52 CAL0002515 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 invasive growth: decreased solid SLAD media C. albicans orf19.1915 ORF MPP10 CAL0002520 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.192 ORF CAL0003270 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.192 ORF CAL0003270 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.192 ORF CAL0003270 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.192 ORF CAL0003270 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.1920 ORF CAL0002533 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.1920 ORF CAL0002533 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.1920 ORF CAL0002533 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.1920 ORF CAL0002533 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.1923 ORF RRN3 CAL0002535 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.1926 ORF SEF2 CAL0002540 PMID: 20041210|CGD_REF: CAL0124764 homozygous diploid, systematic mutation set null SN152 metal resistance: decreased copper(2+) strongly sensitive C. albicans orf19.1934 ORF HST3 CAL0002561 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.1934 ORF HST3 CAL0002561 PMID: 21749487|CGD_REF: CAL0000142507 heterozygous diploid, classical genetics null HST3/hst3::FRT WO-1 phenotypic switching: increased mutants display increased white-to-opaque switching C. albicans orf19.1934 ORF HST3 CAL0002561 PMID: 21749487|CGD_REF: CAL0000142507 heterozygous diploid, classical genetics overexpression HST3/hst3::FRT WO-1 phenotypic switching: decreased ectopic expression of HST3 blocks genotoxin induced white-to-opaque switching C. albicans orf19.1934 ORF HST3 CAL0002561 PMID: 20601951|CGD_REF: CAL0125877 heterozygous diploid, classical genetics null hst3-delta/HST3+ Other C. albicans resistance to chemicals: decreased hydroxyurea (10 mM) C. albicans orf19.1934 ORF HST3 CAL0002561 PMID: 20601951|CGD_REF: CAL0125877 heterozygous diploid, classical genetics null hst3-delta/HST3+ Other C. albicans resistance to chemicals: decreased methyl methanesulfonate (0.005%) C. albicans orf19.1934 ORF HST3 CAL0002561 PMID: 20601951|CGD_REF: CAL0125877 heterozygous diploid, classical genetics repressible hst3-delta/pTET-HST3 Other C. albicans vegetative growth: decreased plus doxycycline (repressed) C. albicans orf19.1934 ORF HST3 CAL0002561 PMID: 20601951|CGD_REF: CAL0125877 heterozygous diploid, classical genetics repressible hst3-delta/pTET-HST3 Other C. albicans protein/peptide modification: increased H3K56 C. albicans orf19.1934 ORF HST3 CAL0002561 PMID: 20601951|CGD_REF: CAL0125877 heterozygous diploid, classical genetics repressible hst3-delta/pTET-HST3 Other C. albicans filamentous growth: increased plus doxycycline (repressed) repression of HST3 under yeast growth conditions triggers the conversion to filamentous growth C. albicans orf19.1934 ORF HST3 CAL0002561 PMID: 20601951|CGD_REF: CAL0125877 homozygous diploid, classical genetics null Other C. albicans inviable deletion of both copies of HST3 not obtained except in a rtt109/rtt109 null background C. albicans orf19.1934 ORF HST3 CAL0002561 PMID: 20601951|CGD_REF: CAL0125877 homozygous diploid, classical genetics null hst3-delta/pTET-HST3 Other C. albicans virulence: decreased plus doxycyclin (repressed) clinical symptoms typical of infection not visible and reduced kidney fungal burden mouse intravenous infection (A/J mice) C. albicans orf19.1934 ORF HST3 CAL0002561 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient YPD medium C. albicans orf19.1934 ORF HST3 CAL0002561 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient SC medium C. albicans orf19.1935 ORF CAL0002563 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient SLAD medium C. albicans orf19.1936 ORF SNF1 CAL0002564 PMID: 9393775|CGD_REF: CAL0081924 homozygous diploid, classical genetics null CAI-4 inviable homozygous null mutant strain could not be recovered, suggesting that the gene is essential under the selection conditions C. albicans orf19.1936 ORF SNF1 CAL0002564 PMID: 9393775|CGD_REF: CAL0081924 heterozygous diploid, classical genetics null CAI-4 filamentous growth: increased C. albicans orf19.1936 ORF SNF1 CAL0002564 PMID: 9393775|CGD_REF: CAL0081924 heterozygous diploid, classical genetics null CAI-4 vegetative growth: decreased rate C. albicans orf19.1936 ORF SNF1 CAL0002564 PMID: 9393775|CGD_REF: CAL0081924 heterozygous diploid, classical genetics null CAI-4 virulence: normal mouse intravenous infection C. albicans orf19.1938 ORF CAL0002567 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient YPD medium C. albicans orf19.1938 ORF CAL0002567 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient SC medium C. albicans orf19.1938 ORF CAL0002567 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient YNB medium C. albicans orf19.1938 ORF CAL0002567 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient SLAD medium C. albicans orf19.1939 ORF CAL0002569 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.194 ORF CAL0003276 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: decreased growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.194 ORF CAL0003276 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.194 ORF CAL0003276 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: decreased rate liquid synthetic complete medium C. albicans orf19.194 ORF CAL0003276 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.1940 ORF CAL0002581 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.1941 ORF NUF2 CAL0002582 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.1942 ORF SGE1 CAL0002583 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.1944 ORF GPR1 CAL0002585 PMID: 15667329|CGD_REF: CAL0103937 homozygous diploid, classical genetics null SC5314 hyphal growth: abnormal defect in hyphal induction in response to low glucose (also fructose, maltose, sucrose or galactose) in minimal medium plus methionine; homozygous gpr1D mutant C. albicans orf19.1944 ORF GPR1 CAL0002585 PMID: 15302825|CGD_REF: CAL0082074 homozygous diploid, classical genetics null CAI-4 hyphal growth: decreased liquid Spider medium slight decrease C. albicans orf19.1944 ORF GPR1 CAL0002585 PMID: 15302825|CGD_REF: CAL0082074 homozygous diploid, classical genetics null CAI-4 hyphal growth: normal liquid serum-containing medium C. albicans orf19.1944 ORF GPR1 CAL0002585 PMID: 15302825|CGD_REF: CAL0082074 heterozygous diploid, classical genetics null Not recorded viable C. albicans orf19.1944 ORF GPR1 CAL0002585 PMID: 15302825|CGD_REF: CAL0082074 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.1944 ORF GPR1 CAL0002585 PMID: 15673611|CGD_REF: CAL0082754 heterozygous diploid, classical genetics null Not recorded viable C. albicans orf19.1944 ORF GPR1 CAL0002585 PMID: 15673611|CGD_REF: CAL0082754 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.1944 ORF GPR1 CAL0002585 PMID: 15673611|CGD_REF: CAL0082754 homozygous diploid, classical genetics null CAI-4 invasive growth: decreased embedded in agar C. albicans orf19.1944 ORF GPR1 CAL0002585 PMID: 15302825|CGD_REF: CAL0082074 homozygous diploid, classical genetics null CAI-4 filamentous growth: decreased solid FBS or Spider media decreased filamentation is suppressed by dbcAMP (cAMP derivative) C. albicans orf19.1944 ORF GPR1 CAL0002585 PMID: 15673611|CGD_REF: CAL0082754 homozygous diploid, classical genetics null CAI-4 filamentous growth: decreased liquid Spider; solid serum, Spider, SLAD, or Lee's media decreases also observed in proline- or methionine-induced filamentation, and in filamentation in an ex vivo human skin model or a systemic mouse infection model C. albicans orf19.1944 ORF GPR1 CAL0002585 PMID: 15302825|CGD_REF: CAL0082074 homozygous diploid, classical genetics null CAI-4 filamentous growth: decreased embedded in agar C. albicans orf19.1944 ORF GPR1 CAL0002585 PMID: 15302825|CGD_REF: CAL0082074 heterozygous diploid, classical genetics overexpression CAI-4 filamentous growth: increased C. albicans orf19.1944 ORF GPR1 CAL0002585 PMID: 15714240|CGD_REF: CAL0103923 homozygous diploid, classical genetics null BWP17 filamentous growth: absent embedded in rich medium C. albicans orf19.1944 ORF GPR1 CAL0002585 PMID: 15302825|CGD_REF: CAL0082074 heterozygous diploid, classical genetics null Not recorded virulence: normal mouse intravenous infection C. albicans orf19.1944 ORF GPR1 CAL0002585 PMID: 15302825|CGD_REF: CAL0082074 homozygous diploid, classical genetics null Not recorded virulence: normal mouse intravenous infection C. albicans orf19.1944 ORF GPR1 CAL0002585 PMID: 15673611|CGD_REF: CAL0082754 homozygous diploid, classical genetics null Not recorded virulence: decreased mouse intravenous infection C. albicans orf19.1944 ORF GPR1 CAL0002585 PMID: 15673611|CGD_REF: CAL0082754 heterozygous diploid, classical genetics null Not recorded virulence: normal mouse intravenous infection C. albicans orf19.1944 ORF GPR1 CAL0002585 PMID: 22952228|CGD_REF: CAL0000157834 homozygous diploid, classical genetics null CAI-4 filamentous growth: absent 37 degree C temperature stimulus C. albicans orf19.1944 ORF GPR1 CAL0002585 PMID: 22952228|CGD_REF: CAL0000157834 homozygous diploid, classical genetics null CAI-4 chemical compound accumulation: increased trehalose 37 degree C exponentially growing cells do not normally make significant amounts of trhalose C. albicans orf19.1945 ORF AUR1 CAL0002586 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.1945 ORF AUR1 CAL0002586 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, competitive growth (haploinsufficient phenotype assay, barcode deletion set) null SC5314 resistance to chemicals: decreased Aureobasidin A C. albicans orf19.1945 ORF AUR1 CAL0002586 PMID: 21135205|CGD_REF: CAL0139967 heterozygous diploid, large-scale survey (large-scale identification of genes essential for virulence in mouse) repressible CAI-4 virulence: absent mouse intravenous infection C. albicans orf19.1946 ORF CAL0002587 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.1949 ORF VPS1 CAL0002589 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.1949 ORF VPS1 CAL0002589 PMID: 18296085|CGD_REF: CAL0118903 homozygous diploid, classical genetics null Not recorded inviable homozygous null mutant strain could not be recovered, suggesting that the gene is essential under the selection conditions C. albicans orf19.1949 ORF VPS1 CAL0002589 PMID: 18296085|CGD_REF: CAL0118903 heterozygous diploid, classical genetics repressible CAI-8 filamentous growth: decreased decreased and delayed filamentation C. albicans orf19.1949 ORF VPS1 CAL0002589 PMID: 18296085|CGD_REF: CAL0118903 heterozygous diploid, classical genetics repressible Not recorded resistance to chemicals: decreased fluconazole C. albicans orf19.1949 ORF VPS1 CAL0002589 PMID: 18296085|CGD_REF: CAL0118903 heterozygous diploid, classical genetics repressible BWP17 biofilm formation: abnormal C. albicans orf19.1950 ORF CAL0002596 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.1953 ORF CAL0002599 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.1953 ORF CAL0002599 PMID: 14663094|CGD_REF: CAL0080633 homozygous diploid, systematic mutation set (homozygous insertion mutants generated with URA3-ARG4-URA3 (UAU1) cassette) null BWP17 viable C. albicans orf19.1954 ORF PUS4 CAL0002600 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.1954 ORF PUS4 CAL0002600 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient YPD medium C. albicans orf19.1954 ORF PUS4 CAL0002600 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient SC medium C. albicans orf19.1954 ORF PUS4 CAL0002600 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient SLAD medium C. albicans orf19.1957 ORF CYC3 CAL0002603 PMID: 9786186|CGD_REF: CAL0081101 homozygous diploid, classical genetics null Not recorded germ tube formation: decreased Lee's medium C. albicans orf19.1957 ORF CYC3 CAL0002603 PMID: 9786186|CGD_REF: CAL0081101 homozygous diploid, classical genetics null Not recorded vegetative growth: decreased rate C. albicans orf19.1957 ORF CYC3 CAL0002603 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.1957 ORF CYC3 CAL0002603 PMID: 9786186|CGD_REF: CAL0081101 heterozygous diploid, classical genetics null Not recorded viable wild-type growth rate C. albicans orf19.1957 ORF CYC3 CAL0002603 PMID: 9786186|CGD_REF: CAL0081101 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.1957 ORF CYC3 CAL0002603 PMID: 9786186|CGD_REF: CAL0081101 homozygous diploid, classical genetics null Not recorded utilization of carbon source: absent lactic acid C. albicans orf19.1960 ORF CLN3 CAL0002632 PMID: 15643064|CGD_REF: CAL0082463 heterozygous diploid, classical genetics repressible BWP17 hyphal growth: abnormal liquid serum-containing media or pH 7.0 at 37 deg C abnormal hyphal morphology C. albicans orf19.1960 ORF CLN3 CAL0002632 PMID: 15643065|CGD_REF: CAL0082434 heterozygous diploid, classical genetics repressible CAI-4 hyphal growth: abnormal abnormal morphology of environmentally induced hyphae C. albicans orf19.1960 ORF CLN3 CAL0002632 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.1960 ORF CLN3 CAL0002632 PMID: 15643065|CGD_REF: CAL0082434 heterozygous diploid, classical genetics repressible Not recorded budding: absent cells become enlarged and then begin filamentous growth C. albicans orf19.1960 ORF CLN3 CAL0002632 PMID: 12524333|CGD_REF: CAL0080691 homozygous diploid, systematic mutation set (homozygous insertion mutants generated with URA3-ARG4-URA3 (UAU1) cassette) null BWP17 inviable homozygous null mutant strain could not be recovered, suggesting that the gene is essential under the selection conditions C. albicans orf19.1960 ORF CLN3 CAL0002632 PMID: 15643064|CGD_REF: CAL0082463 homozygous diploid, classical genetics null Not recorded inviable homozygous null mutant strain could not be recovered, suggesting that the gene is essential under the selection conditions C. albicans orf19.1960 ORF CLN3 CAL0002632 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, competitive growth (haploinsufficient phenotype assay, barcode deletion set) null SC5314 resistance to chemicals: decreased amphotericin B C. albicans orf19.1960 ORF CLN3 CAL0002632 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 invasive growth: decreased solid SLAD media C. albicans orf19.1964 ORF CAL0002636 PMID: 21414038|CGD_REF: CAL0141808 homozygous diploid, classical genetics null BWP17 viable C. albicans orf19.1966 ORF BUD23 CAL0002637 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.1971 ORF TRY3 CAL0002668 PMID: 22359502|CGD_REF: CAL0000144048 homozygous diploid, classical genetics null BWP17 viable C. albicans orf19.1971 ORF TRY3 CAL0002668 PMID: 22359502|CGD_REF: CAL0000144048 homozygous diploid, classical genetics null BWP17 adhesion: decreased C. albicans orf19.1971 ORF TRY3 CAL0002668 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 invasive growth: decreased solid SLAD media C. albicans orf19.1973 ORF HAP5 CAL0002670 PMID: 20041210|CGD_REF: CAL0124764 homozygous diploid, systematic mutation set null SN152 resistance to chemicals: decreased BPS (500 uM bathophenanthrolinedisulfonic?acid, an iron chelator) strongly sensitive C. albicans orf19.1973 ORF HAP5 CAL0002670 PMID: 16215174|CGD_REF: CAL0114835 homozygous diploid, classical genetics null Not recorded vegetative growth: decreased rate C. albicans orf19.1973 ORF HAP5 CAL0002670 PMID: 18503007|CGD_REF: CAL0119016 homozygous diploid, classical genetics null Not recorded vegetative growth: normal rate solid YPG medium C. albicans orf19.1973 ORF HAP5 CAL0002670 PMID: 20041210|CGD_REF: CAL0124764 homozygous diploid, systematic mutation set null SN152 vegetative growth: decreased Lee's pH 4.5 medium at 30 deg C strongly decreased C. albicans orf19.1973 ORF HAP5 CAL0002670 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.1973 ORF HAP5 CAL0002670 PMID: 16215174|CGD_REF: CAL0114835 heterozygous diploid, classical genetics null Not recorded viable C. albicans orf19.1973 ORF HAP5 CAL0002670 PMID: 16215174|CGD_REF: CAL0114835 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.1973 ORF HAP5 CAL0002670 PMID: 18503007|CGD_REF: CAL0119016 heterozygous diploid, classical genetics null Not recorded viable C. albicans orf19.1973 ORF HAP5 CAL0002670 PMID: 18503007|CGD_REF: CAL0119016 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.1973 ORF HAP5 CAL0002670 PMID: 20041210|CGD_REF: CAL0124764 homozygous diploid, systematic mutation set null SN152 resistance to chemicals: increased rapamycin strongly resistant C. albicans orf19.1973 ORF HAP5 CAL0002670 PMID: 20041210|CGD_REF: CAL0124764 homozygous diploid, systematic mutation set null SN152 alkaline pH resistance: decreased pH 10.5 strongly sensitive C. albicans orf19.1973 ORF HAP5 CAL0002670 PMID: 16215174|CGD_REF: CAL0114835 homozygous diploid, classical genetics null BWP17 filamentous growth: increased solid alkaline M199 medium, poor carbon sources filamentation is wild-type in some liquid media C. albicans orf19.1973 ORF HAP5 CAL0002670 PMID: 16215174|CGD_REF: CAL0114835 homozygous diploid, classical genetics null BWP17 filamentous growth: decreased serum-containing, Spider, or Lee's solid media, and liquid Spider medium C. albicans orf19.1973 ORF HAP5 CAL0002670 PMID: 18503007|CGD_REF: CAL0119016 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased iron chelators C. albicans orf19.1973 ORF HAP5 CAL0002670 PMID: 18503007|CGD_REF: CAL0119016 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased iron chelators C. albicans orf19.1973 ORF HAP5 CAL0002670 PMID: 20041210|CGD_REF: CAL0124764 homozygous diploid, systematic mutation set null SN152 metal resistance: increased copper(2+) strongly resistant C. albicans orf19.1973 ORF HAP5 CAL0002670 PMID: 21592964|CGD_REF: CAL0142015 homozygous diploid, classical genetics null SN152 RNA accumulation: decreased SIT1 mRNA C. albicans orf19.1973 ORF HAP5 CAL0002670 PMID: 21592964|CGD_REF: CAL0142015 homozygous diploid, classical genetics null SN152 RNA accumulation: decreased FRP1 mRNA C. albicans orf19.1973 ORF HAP5 CAL0002670 PMID: 21592964|CGD_REF: CAL0142015 homozygous diploid, classical genetics null SN152 RNA accumulation: decreased HMX1 mRNA C. albicans orf19.1973 ORF HAP5 CAL0002670 PMID: 21592964|CGD_REF: CAL0142015 homozygous diploid, classical genetics null SN152 RNA accumulation: increased ACO1 mRNA C. albicans orf19.1973 ORF HAP5 CAL0002670 PMID: 22365851|CGD_REF: CAL0000144076 homozygous diploid, classical genetics null SN95 filamentous growth: absent mutant did not filament in response to geldanamycin or elevated temperature (42 degrees C) C. albicans orf19.1975 ORF CAL0002672 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.1977 ORF URA4 CAL0002674 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.1978 ORF GIT2 CAL0002675 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.1979 ORF GIT3 CAL0002676 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.1980 ORF GIT4 CAL0002702 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.1980 ORF GIT4 CAL0002702 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 invasive growth: decreased solid SLAD media C. albicans orf19.1986 ORF ARO2 CAL0002708 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.1986 ORF ARO2 CAL0002708 PMID: 21135205|CGD_REF: CAL0139967 heterozygous diploid, large-scale survey (large-scale identification of genes essential for virulence in mouse) repressible CAI-4 virulence: absent mouse intravenous infection C. albicans orf19.1988 ORF CDC45 CAL0002709 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.1989 ORF DCW1 CAL0002710 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.1989 ORF DCW1 CAL0002710 PMID: 12912894|CGD_REF: CAL0081137 homozygous diploid, classical genetics null Not recorded viable no apparent phenotype C. albicans orf19.199 ORF CAL0003292 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.199 ORF CAL0003292 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.199 ORF CAL0003292 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: decreased rate liquid synthetic complete medium C. albicans orf19.199 ORF CAL0003292 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.199 ORF CAL0003292 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 invasive growth: decreased solid SLAD media C. albicans orf19.1990 ORF SNX4 CAL0002737 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.1991 ORF CAL0002738 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.1992 ORF SIR2 CAL0002739 PMID: 18691183|CGD_REF: CAL0119368 heterozygous diploid, classical genetics null Not recorded silencing: decreased defect in silencing of a reporter inserted at the rDNA locus C. albicans orf19.1992 ORF SIR2 CAL0002739 PMID: 10228170|CGD_REF: CAL0081917 heterozygous diploid, classical genetics overexpression Not recorded vegetative growth: decreased rate slight decrease C. albicans orf19.1992 ORF SIR2 CAL0002739 PMID: 10228170|CGD_REF: CAL0081917 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.1992 ORF SIR2 CAL0002739 PMID: 18691183|CGD_REF: CAL0119368 heterozygous diploid, classical genetics null BWP17 viable C. albicans orf19.1992 ORF SIR2 CAL0002739 PMID: 18691183|CGD_REF: CAL0119368 aneuploid, classical genetics overexpression BWP17 viable C. albicans orf19.1992 ORF SIR2 CAL0002739 PMID: 19555456|CGD_REF: CAL0123821 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.1992 ORF SIR2 CAL0002739 PMID: 10228170|CGD_REF: CAL0081917 homozygous diploid, classical genetics null Not recorded chromosome/plasmid maintenance: abnormal ribosomal DNA (rDNA) minichromosomes are formed C. albicans orf19.1992 ORF SIR2 CAL0002739 PMID: 18691183|CGD_REF: CAL0119368 heterozygous diploid, classical genetics null Not recorded lifespan: decreased duration C. albicans orf19.1992 ORF SIR2 CAL0002739 PMID: 18691183|CGD_REF: CAL0119368 homozygous diploid, classical genetics null Not recorded lifespan: decreased duration C. albicans orf19.1992 ORF SIR2 CAL0002739 PMID: 10228170|CGD_REF: CAL0081917 heterozygous diploid, classical genetics repressible Not recorded filamentous growth: increased solid or liquid rich media C. albicans orf19.1992 ORF SIR2 CAL0002739 PMID: 10228170|CGD_REF: CAL0081917 homozygous diploid, classical genetics null Not recorded phenotypic switching: increased switching among variant colony morphologies C. albicans orf19.1992 ORF SIR2 CAL0002739 PMID: 10228170|CGD_REF: CAL0081917 heterozygous diploid, classical genetics repressible Not recorded phenotypic switching: increased switching among variant colony morphologies C. albicans orf19.1992 ORF SIR2 CAL0002739 PMID: 18691183|CGD_REF: CAL0119368 homozygous diploid, classical genetics null Not recorded protein transport: abnormal oxidatively damaged proteins are distributed equally between mother and bud, rather than being distributed asymmetrically as in wild type C. albicans orf19.1992 ORF SIR2 CAL0002739 PMID: 18691183|CGD_REF: CAL0119368 aneuploid, classical genetics overexpression BWP17 replicative lifespan: increased increased gene dosage by insertion of additional copy of the gene C. albicans orf19.1995 ORF MNN24 CAL0002742 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.1995 ORF MNN24 CAL0002742 PMID: 23633946|CGD_REF: CAL0000172007 homozygous diploid, classical genetics null mnn24::dpl200/mnn24::dpl200 CAI-4 virulence: decreased mannan mutant allow increased survival time of larvae other model (G. mellonella larvae) C. albicans orf19.1995 ORF MNN24 CAL0002742 PMID: 23633946|CGD_REF: CAL0000172007 homozygous diploid, classical genetics null mnn24::dpl200/mnn24::dpl200 CAI-4 chemical compound accumulation: decreased mannan C. albicans orf19.1996 ORF CHA1 CAL0002743 PMID: 12773383|CGD_REF: CAL0087974 heterozygous diploid, classical genetics (haploinsufficient phenotype assay) null CAI-4 viable heterozygous transposon insertion C. albicans orf19.1996 ORF CHA1 CAL0002743 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.20 ORF RTS1 CAL0000518 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.2000 ORF CAL0004313 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.2000 ORF CAL0004313 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 invasive growth: decreased solid SLAD media C. albicans orf19.2002 ORF CAL0004316 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.2003 ORF HNM1 CAL0004318 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.2003 ORF HNM1 CAL0004318 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, competitive growth (haploinsufficient phenotype assay, barcode deletion set) null SC5314 resistance to chemicals: decreased ergosterol analogs (ECC69 and/or ECC1384) C. albicans orf19.2005 ORF REG1 CAL0004320 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.2007 ORF CAL0004322 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.2012 ORF NOT3 CAL0004330 PMID: 14500538|CGD_REF: CAL0081606 homozygous diploid, classical genetics null Not recorded viable liquid YPD at 37 deg C wild-type growth rate C. albicans orf19.2012 ORF NOT3 CAL0004330 PMID: 14500538|CGD_REF: CAL0081606 homozygous diploid, classical genetics null Not recorded adhesion: normal adhesion to human buccal epithelial cells C. albicans orf19.2012 ORF NOT3 CAL0004330 PMID: 14500538|CGD_REF: CAL0081606 homozygous diploid, classical genetics null CAI-4 filamentous growth: abnormal solid M199 or Spider media reduced filamentation ratio of colonies C. albicans orf19.2012 ORF NOT3 CAL0004330 PMID: 22359502|CGD_REF: CAL0000144048 homozygous diploid, classical genetics null BWP17 adhesion: decreased independent insertion mutant isolates tested C. albicans orf19.2012 ORF NOT3 CAL0004330 PMID: 22359502|CGD_REF: CAL0000144048 homozygous diploid, classical genetics null BWP17 viable independent insertion mutant isolates tested C. albicans orf19.2012 ORF NOT3 CAL0004330 PMID: 14500538|CGD_REF: CAL0081606 homozygous diploid, classical genetics null Not recorded virulence: normal mouse intravenous infection C. albicans orf19.2013 ORF KAR2 CAL0004332 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.2013 ORF KAR2 CAL0004332 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: increased growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.2013 ORF KAR2 CAL0004332 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.2013 ORF KAR2 CAL0004332 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.2013 ORF KAR2 CAL0004332 PMID: 20886215|CGD_REF: CAL0126490 heterozygous diploid, classical genetics repressible kar2Δ::UAU1/MET3p-KAR2 BWP17 inviable repressing conditions (2.5 mM methionine and cysteine in growth media) C. albicans orf19.2013 ORF KAR2 CAL0004332 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.2013 ORF KAR2 CAL0004332 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 invasive growth: decreased solid SLAD media C. albicans orf19.2014 ORF BCY1 CAL0004334 PMID: 14523129|CGD_REF: CAL0080787 homozygous diploid, classical genetics overexpression CAI-4 germ tube formation: decreased solid and liquid media or embedded in agar C. albicans orf19.2014 ORF BCY1 CAL0004334 PMID: 19391100|CGD_REF: CAL0122781 heterozygous diploid, classical genetics null Not recorded thermotolerance: decreased C. albicans orf19.2014 ORF BCY1 CAL0004334 PMID: 14523129|CGD_REF: CAL0080787 homozygous diploid, classical genetics overexpression CAI-4 hyphal growth: decreased solid and liquid media or embedded in agar C. albicans orf19.2014 ORF BCY1 CAL0004334 PMID: 16473139|CGD_REF: CAL0115529 heterozygous diploid, classical genetics null CAI-4 hyphal growth: abnormal liquid GlcNAc-containing or Lee's media C. albicans orf19.2014 ORF BCY1 CAL0004334 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.2014 ORF BCY1 CAL0004334 PMID: 14871949|CGD_REF: CAL0080788 heterozygous diploid, classical genetics null Not recorded viable C. albicans orf19.2014 ORF BCY1 CAL0004334 PMID: 12524333|CGD_REF: CAL0080691 homozygous diploid, systematic mutation set (homozygous insertion mutants generated with URA3-ARG4-URA3 (UAU1) cassette) null BWP17 inviable homozygous null mutant strain could not be recovered, suggesting that the gene is essential under the selection conditions C. albicans orf19.2014 ORF BCY1 CAL0004334 PMID: 14871949|CGD_REF: CAL0080788 homozygous diploid, classical genetics null Not recorded inviable C. albicans orf19.2014 ORF BCY1 CAL0004334 PMID: 19391100|CGD_REF: CAL0122781 heterozygous diploid, classical genetics null CAI-4 filamentous growth: abnormal cells germinate as a mixture of hyphae and pseudohyphae C. albicans orf19.2016 ORF ERG28 CAL0004337 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.2017 ORF CAL0004338 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.2019 ORF CAL0004340 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.2019 ORF CAL0004340 PMID: 21135205|CGD_REF: CAL0139967 heterozygous diploid, competitive growth (large-scale identification of genes essential for virulence in mouse) repressible CAI-4 virulence: decreased mouse intravenous infection C. albicans orf19.202 ORF CDC47 CAL0003868 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.2020 ORF HGT6 CAL0004351 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.2020 ORF HGT6 CAL0004351 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.2020 ORF HGT6 CAL0004351 PMID: 21414038|CGD_REF: CAL0141808 homozygous diploid, classical genetics null BWP17 viable C. albicans orf19.2020 ORF HGT6 CAL0004351 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.2020 ORF HGT6 CAL0004351 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.2020 ORF HGT6 CAL0004351 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.2021 ORF HGT8 CAL0004354 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: decreased growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.2021 ORF HGT8 CAL0004354 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.2021 ORF HGT8 CAL0004354 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.2021 ORF HGT8 CAL0004354 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.2023 ORF HGT7 CAL0004358 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.2023 ORF HGT7 CAL0004358 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, competitive growth (haploinsufficient phenotype assay, barcode deletion set) null SC5314 resistance to chemicals: decreased amphotericin B C. albicans orf19.2023 ORF HGT7 CAL0004358 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, competitive growth (haploinsufficient phenotype assay, barcode deletion set) null SC5314 resistance to chemicals: decreased ergosterol analogs (ECC69 and/or ECC1384) C. albicans orf19.2023 ORF HGT7 CAL0004358 PMID: 21414038|CGD_REF: CAL0141808 homozygous diploid, classical genetics null BWP17 viable C. albicans orf19.2026 ORF UBP13 CAL0004364 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.2028 ORF MXR1 CAL0004365 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.2029 ORF RFC5 CAL0004366 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.2031 ORF VPS24 CAL0004377 PMID: 15371534|CGD_REF: CAL0082134 homozygous diploid, classical genetics null BWP17 hyphal growth: normal solid medium, alkaline pH C. albicans orf19.2031 ORF VPS24 CAL0004377 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.2031 ORF VPS24 CAL0004377 PMID: 15371534|CGD_REF: CAL0082134 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.2031 ORF VPS24 CAL0004377 PMID: 18466294|CGD_REF: CAL0119004 homozygous diploid, classical genetics null Not recorded utilization of iron source: absent hemoglobin C. albicans orf19.2031 ORF VPS24 CAL0004377 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient SLAD medium C. albicans orf19.2033 ORF PGA19 CAL0004383 PMID: 14663094|CGD_REF: CAL0080633 homozygous diploid, systematic mutation set (homozygous insertion mutants generated with URA3-ARG4-URA3 (UAU1) cassette) null BWP17 viable C. albicans orf19.2036 ORF CAL0004389 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.2038 ORF CAL0004391 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient YPD medium C. albicans orf19.2038 ORF CAL0004391 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient SLAD medium C. albicans orf19.2039 ORF MSF1 CAL0004392 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.2040 ORF CAL0004403 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.2041 ORF CAL0004406 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.2043 ORF CAL0004410 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.2044 ORF PGA27 CAL0004412 PMID: 18765290|CGD_REF: CAL0119430 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.2044 ORF PGA27 CAL0004412 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 invasive growth: decreased solid SLAD media C. albicans orf19.2045 ORF CAL0004414 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.2046 ORF POT1-2 CAL0004416 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.2046 ORF POT1-2 CAL0004416 PMID: 23758791|CGD_REF: CAL0000172382 homozygous diploid, classical genetics null SC5314 viable C. albicans orf19.2047 ORF CAL0004417 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.2047 ORF CAL0004417 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, competitive growth (haploinsufficient phenotype assay, barcode deletion set) null SC5314 resistance to chemicals: decreased amphotericin B C. albicans orf19.2047 ORF CAL0004417 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, competitive growth (haploinsufficient phenotype assay, barcode deletion set) null SC5314 resistance to chemicals: decreased ergosterol analogs (ECC69 and/or ECC1384) C. albicans orf19.2049 ORF CAL0004419 PMID: 19115836|CGD_REF: CAL0122036 heterozygous diploid, competitive growth (haploinsufficient phenotype assay, barcode deletion set) null SC5314 resistance to chemicals: decreased virgineone C. albicans orf19.2050 ORF CAL0004431 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.2054 ORF FGR15 CAL0004440 PMID: 20041210|CGD_REF: CAL0124764 homozygous diploid, systematic mutation set null SN152 heat sensitivity: increased elevated temperature (42 deg C, YEPD or SD medium) strongly sensitive C. albicans orf19.2054 ORF FGR15 CAL0004440 PMID: 15964282|CGD_REF: CAL0114274 homozygous diploid, systematic mutation set (split-marker transposon insertion strategy to disrupt both alleles) null BWP17 viable C. albicans orf19.2054 ORF FGR15 CAL0004440 PMID: 16552442|CGD_REF: CAL0115731 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.2054 ORF FGR15 CAL0004440 PMID: 15964282|CGD_REF: CAL0114274 homozygous diploid, systematic mutation set (split-marker transposon insertion strategy to disrupt both alleles) null BWP17 biofilm formation: normal C. albicans orf19.2054 ORF FGR15 CAL0004440 PMID: 20041210|CGD_REF: CAL0124764 homozygous diploid, systematic mutation set null SN152 cold sensitivity: increased reduced temperature (16 deg C, YEPD or SD medium) strongly sensitive C. albicans orf19.2054 ORF FGR15 CAL0004440 PMID: 20041210|CGD_REF: CAL0124764 homozygous diploid, systematic mutation set null SN152 colony appearance: abnormal Spider medium strongly increased colony wrinkling C. albicans orf19.2054 ORF FGR15 CAL0004440 PMID: 12773383|CGD_REF: CAL0087974 heterozygous diploid, classical genetics (haploinsufficient phenotype assay) unspecified CAI-4 filamentous growth: abnormal solid Spider medium increased or decreased filamentous growth, depending on the allele; heterozygous transposon insertion C. albicans orf19.2054 ORF FGR15 CAL0004440 PMID: 16552442|CGD_REF: CAL0115731 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased caspofungin effect is slight C. albicans orf19.2055 ORF NPL6 CAL0004441 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.2055 ORF NPL6 CAL0004441 PMID: 21135205|CGD_REF: CAL0139967 heterozygous diploid, large-scale survey (large-scale identification of genes essential for virulence in mouse) repressible CAI-4 virulence: absent mouse intravenous infection C. albicans orf19.2057 ORF CAL0004443 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.2059 ORF CAL0004444 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.206 ORF CAL0003872 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.206 ORF CAL0003872 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.206 ORF CAL0003872 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.206 ORF CAL0003872 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.2060 ORF SOD5 CAL0004456 PMID: 14617819|CGD_REF: CAL0081198 heterozygous diploid, classical genetics null Not recorded viable C. albicans orf19.2060 ORF SOD5 CAL0004456 PMID: 14617819|CGD_REF: CAL0081198 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.2060 ORF SOD5 CAL0004456 PMID: 15813733|CGD_REF: CAL0104041 heterozygous diploid, classical genetics null Not recorded viable C. albicans orf19.2060 ORF SOD5 CAL0004456 PMID: 19019164|CGD_REF: CAL0121070 heterozygous diploid, classical genetics null Not recorded interaction with host/environment: normal wild-type reactive oxygen species accumulation during response to macrophages in vitro model of infection C. albicans orf19.2060 ORF SOD5 CAL0004456 PMID: 14617819|CGD_REF: CAL0081198 heterozygous diploid, classical genetics null Not recorded oxidative stress resistance: decreased hydrogen peroxide minimal media C. albicans orf19.2060 ORF SOD5 CAL0004456 PMID: 14617819|CGD_REF: CAL0081198 homozygous diploid, classical genetics null Not recorded oxidative stress resistance: decreased hydrogen peroxide minimal media C. albicans orf19.2060 ORF SOD5 CAL0004456 PMID: 19019164|CGD_REF: CAL0121070 homozygous diploid, classical genetics null Not recorded chemical compound accumulation: increased reactive oxygen species during infection of macrophages or dendritic cells; reversed by exogenous commercial bovine erythrocyte SOD enzyme C. albicans orf19.2060 ORF SOD5 CAL0004456 PMID: 15813733|CGD_REF: CAL0104041 homozygous diploid, classical genetics null CAI-4 viable C. albicans orf19.2060 ORF SOD5 CAL0004456 PMID: 19019164|CGD_REF: CAL0121070 homozygous diploid, classical genetics null SN152 viable C. albicans orf19.2060 ORF SOD5 CAL0004456 PMID: 19019164|CGD_REF: CAL0121070 homozygous diploid, classical genetics null SN152 induction of host response: increased increased host ROS production in infected bone marrow-derived macrophages C. albicans orf19.2060 ORF SOD5 CAL0004456 PMID: 14617819|CGD_REF: CAL0081198 homozygous diploid, classical genetics null CAI-4 resistance to killing by host cells: normal in vitro model of infection (RAW264.7 macrophages) C. albicans orf19.2060 ORF SOD5 CAL0004456 PMID: 19019164|CGD_REF: CAL0121070 homozygous diploid, classical genetics null SN152 resistance to killing by host cells: decreased hypersensitive to killing by innate immune response; rescued by exogenous commercial bovine erythrocyte SOD enzyme in vitro model of infection (murine bone marrow-derived macrophages) C. albicans orf19.2060 ORF SOD5 CAL0004456 PMID: 15813733|CGD_REF: CAL0104041 homozygous diploid, classical genetics null CAI-4 resistance to killing by host cells: decreased decreased viability in the presence of blood components in vitro model of infection (human whole blood or granulocytes) C. albicans orf19.2060 ORF SOD5 CAL0004456 PMID: 14617819|CGD_REF: CAL0081198 heterozygous diploid, classical genetics null Not recorded virulence: decreased exhibits decreased kidney colonization mouse intravenous infection C. albicans orf19.2060 ORF SOD5 CAL0004456 PMID: 14617819|CGD_REF: CAL0081198 homozygous diploid, classical genetics null Not recorded virulence: decreased exhibits decreased kidney colonization mouse intravenous infection C. albicans orf19.2060 ORF SOD5 CAL0004456 PMID: 14617819|CGD_REF: CAL0081198 heterozygous diploid, classical genetics null Not recorded virulence: decreased virulence is intermediate between that of the homozygous null mutant and wild type mouse intravenous infection C. albicans orf19.2060 ORF SOD5 CAL0004456 PMID: 14617819|CGD_REF: CAL0081198 homozygous diploid, classical genetics null Not recorded virulence: decreased mouse intravenous infection C. albicans orf19.2060 ORF SOD5 CAL0004456 PMID: 15813733|CGD_REF: CAL0104041 homozygous diploid, classical genetics null Not recorded virulence: decreased mouse intravenous infection C. albicans orf19.2060 ORF SOD5 CAL0004456 PMID: 23285201|CGD_REF: CAL0000158306 homozygous diploid, classical genetics null BWP17 resistance to killing by host cells: decreased human neutrophils C. albicans orf19.2061 ORF CAL0004459 PMID: 14663094|CGD_REF: CAL0080633 homozygous diploid, systematic mutation set (homozygous insertion mutants generated with URA3-ARG4-URA3 (UAU1) cassette) null BWP17 viable C. albicans orf19.2062 ORF SOD4 CAL0004462 PMID: 18765290|CGD_REF: CAL0119430 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.2062 ORF SOD4 CAL0004462 PMID: 19019164|CGD_REF: CAL0121070 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.2062 ORF SOD4 CAL0004462 PMID: 19019164|CGD_REF: CAL0121070 homozygous diploid, classical genetics null Not recorded interaction with host/environment: normal wild-type reactive oxygen species accumulation during response to macrophages in vitro model of infection C. albicans orf19.2063 ORF CAL0004465 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.2063 ORF CAL0004465 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.2063 ORF CAL0004465 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.2063 ORF CAL0004465 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.2064 ORF CAL0004467 PMID: 15964282|CGD_REF: CAL0114274 homozygous diploid, systematic mutation set (split-marker transposon insertion strategy to disrupt both alleles) null BWP17 inviable homozygous null mutant strain could not be recovered, suggesting that the gene is essential under the selection conditions C. albicans orf19.2064 ORF CAL0004467 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.2064 ORF CAL0004467 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.2064 ORF CAL0004467 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.2064 ORF CAL0004467 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.2065 ORF CAL0004469 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.2067 ORF CAL0004471 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.2069 ORF SMF3 CAL0004473 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.207 ORF PGA55 CAL0003874 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.207 ORF PGA55 CAL0003874 PMID: 18765290|CGD_REF: CAL0119430 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.207 ORF PGA55 CAL0003874 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.207 ORF PGA55 CAL0003874 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.207 ORF PGA55 CAL0003874 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.207 ORF PGA55 CAL0003874 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.2070 ORF CAL0004485 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.2072 ORF CAL0004491 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.2073 ORF CAL0004494 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.2073 ORF CAL0004494 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 invasive growth: decreased solid SLAD media C. albicans orf19.2074 ORF CAL0004496 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 invasive growth: decreased solid SLAD media C. albicans orf19.2075 ORF DFG5 CAL0004498 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.2075 ORF DFG5 CAL0004498 PMID: 12912894|CGD_REF: CAL0081137 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.2075 ORF DFG5 CAL0004498 PMID: 18765290|CGD_REF: CAL0119430 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.2075 ORF DFG5 CAL0004498 PMID: 18765290|CGD_REF: CAL0119430 homozygous diploid, classical genetics null Not recorded cell wall morphology: abnormal increased thickness C. albicans orf19.2075 ORF DFG5 CAL0004498 PMID: 12912894|CGD_REF: CAL0081137 homozygous diploid, classical genetics null Other C. albicans filamentous growth: absent alkaline (pH 8) liquid or solid medium C. albicans orf19.2075 ORF DFG5 CAL0004498 PMID: 18765290|CGD_REF: CAL0119430 homozygous diploid, classical genetics null Not recorded resistance to chemicals: increased caspofungin C. albicans orf19.2075 ORF DFG5 CAL0004498 PMID: 18765290|CGD_REF: CAL0119430 homozygous diploid, classical genetics null Not recorded chemical compound accumulation: increased glucan increased cell wall glucan C. albicans orf19.2075 ORF DFG5 CAL0004498 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.2075 ORF DFG5 CAL0004498 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.2075 ORF DFG5 CAL0004498 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.2075 ORF DFG5 CAL0004498 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.2077 ORF ZCF9 CAL0004500 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.2077 ORF ZCF9 CAL0004500 PMID: 15964282|CGD_REF: CAL0114274 homozygous diploid, systematic mutation set (split-marker transposon insertion strategy to disrupt both alleles) null BWP17 inviable homozygous null mutant strain could not be recovered, suggesting that the gene is essential under the selection conditions C. albicans orf19.2077 ORF ZCF9 CAL0004500 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, competitive growth (haploinsufficient phenotype assay, barcode deletion set) null SC5314 resistance to chemicals: decreased ergosterol analogs (ECC69 and/or ECC1384) C. albicans orf19.2077 ORF ZCF9 CAL0004500 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient YPD medium C. albicans orf19.2077 ORF ZCF9 CAL0004500 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient YNB medium C. albicans orf19.2077 ORF ZCF9 CAL0004500 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient SLAD medium C. albicans orf19.2078 ORF CAL0004501 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.2078 ORF CAL0004501 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient YPD medium C. albicans orf19.2078 ORF CAL0004501 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient SC medium C. albicans orf19.2078 ORF CAL0004501 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient YNB medium C. albicans orf19.2079 ORF PHHB CAL0004502 PMID: 12773383|CGD_REF: CAL0087974 heterozygous diploid, classical genetics (haploinsufficient phenotype assay) null CAI-4 viable heterozygous transposon insertion C. albicans orf19.2079 ORF PHHB CAL0004502 PMID: 12773383|CGD_REF: CAL0087974 heterozygous diploid, classical genetics (haploinsufficient phenotype assay) null CAI-4 filamentous growth: abnormal heterozygous transposon insertion C. albicans orf19.2082 ORF SAP30 CAL0004526 PMID: 17416895|CGD_REF: CAL0117926 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.2082 ORF SAP30 CAL0004526 PMID: 19675652|CGD_REF: CAL0123947 homozygous diploid, classical genetics null Not recorded cell shape: abnormal cells are elongated C. albicans orf19.2082 ORF SAP30 CAL0004526 PMID: 17416895|CGD_REF: CAL0117926 homozygous diploid, classical genetics null Not recorded mating efficiency: decreased C. albicans orf19.2082 ORF SAP30 CAL0004526 PMID: 19675652|CGD_REF: CAL0123947 homozygous diploid, classical genetics null Not recorded mating response: abnormal mating-like response in the absence of exogenous pheromone or a mating partner C. albicans orf19.2082 ORF SAP30 CAL0004526 PMID: 19675652|CGD_REF: CAL0123947 homozygous diploid, classical genetics null Not recorded colony appearance: abnormal colonies are wrinkled C. albicans orf19.2082 ORF SAP30 CAL0004526 PMID: 17416895|CGD_REF: CAL0117926 homozygous diploid, classical genetics null Not recorded pheromone sensitivity: increased alpha factor C. albicans orf19.2082 ORF SAP30 CAL0004526 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient YNB medium C. albicans orf19.2084 ORF CDH1 CAL0004530 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.2084 ORF CDH1 CAL0004530 PMID: 21398510|CGD_REF: CAL0141801 homozygous diploid, classical genetics null cdh1::URA3/cdh1::HIS1 BWP17 colony shape: abnormal smaller colonies with uneven edges C. albicans orf19.2084 ORF CDH1 CAL0004530 PMID: 21398510|CGD_REF: CAL0141801 homozygous diploid, classical genetics null cdh1::URA3/cdh1::HIS1 BWP17 cell shape: abnormal liquid YEPD medium 30% pseudohyphae and irregular-shaped cells C. albicans orf19.2084 ORF CDH1 CAL0004530 PMID: 21398510|CGD_REF: CAL0141801 homozygous diploid, classical genetics null cdh1::URA3/cdh1::HIS1 BWP17 viable C. albicans orf19.2087 ORF SAS2 CAL0004532 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.2087 ORF SAS2 CAL0004532 PMID: 19555456|CGD_REF: CAL0123821 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.2087 ORF SAS2 CAL0004532 PMID: 23355007|CGD_REF: CAL0000158487 homozygous diploid, classical genetics null BWP17 viable C. albicans orf19.2087 ORF SAS2 CAL0004532 PMID: 23355007|CGD_REF: CAL0000158487 homozygous diploid, classical genetics null BWP17 heat sensitivity: decreased C. albicans orf19.2088 ORF DPB4 CAL0004533 PMID: 20041210|CGD_REF: CAL0124764 homozygous diploid, systematic mutation set null SN152 vegetative growth: decreased SD or YEPD media at 30 deg C, or blood agar at 37 deg C strongly decreased C. albicans orf19.2088 ORF DPB4 CAL0004533 PMID: 20041210|CGD_REF: CAL0124764 homozygous diploid, systematic mutation set null SN152 invasive growth: increased SD or YEPD media at 30 or 37 deg C strongly increased C. albicans orf19.2088 ORF DPB4 CAL0004533 PMID: 20041210|CGD_REF: CAL0124764 homozygous diploid, systematic mutation set null SN152 colony color: abnormal CHROMagar medium at 30 deg C darker than normal C. albicans orf19.2088 ORF DPB4 CAL0004533 PMID: 24450762|CGD_REF: CAL0000173762 homozygous diploid, classical genetics null Other C. albicans viable C. albicans orf19.2088 ORF DPB4 CAL0004533 PMID: 24450762|CGD_REF: CAL0000173762 homozygous diploid, classical genetics null Other C. albicans vegetative growth: decreased rate C. albicans orf19.2088 ORF DPB4 CAL0004533 PMID: 24450762|CGD_REF: CAL0000173762 homozygous diploid, classical genetics null Other C. albicans colony shape: abnormal C. albicans orf19.2088 ORF DPB4 CAL0004533 PMID: 24450762|CGD_REF: CAL0000173762 homozygous diploid, classical genetics null Other C. albicans invasive growth: decreased C. albicans orf19.2088 ORF DPB4 CAL0004533 PMID: 24450762|CGD_REF: CAL0000173762 homozygous diploid, classical genetics null Other C. albicans resistance to chemicals: decreased Calcofluor White C. albicans orf19.2088 ORF DPB4 CAL0004533 PMID: 24450762|CGD_REF: CAL0000173762 homozygous diploid, classical genetics null Other C. albicans resistance to chemicals: decreased caspofungin C. albicans orf19.2088 ORF DPB4 CAL0004533 PMID: 24450762|CGD_REF: CAL0000173762 homozygous diploid, classical genetics null Other C. albicans respiratory growth: decreased rate C. albicans orf19.2088 ORF DPB4 CAL0004533 PMID: 24450762|CGD_REF: CAL0000173762 homozygous diploid, classical genetics null Other C. albicans mitochondrial genome maintenance: decreased C. albicans orf19.2089 ORF CAL0004534 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient YPD medium C. albicans orf19.209 ORF DFG10 CAL0003877 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.209 ORF DFG10 CAL0003877 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.209 ORF DFG10 CAL0003877 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.209 ORF DFG10 CAL0003877 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.2090 ORF CAL0004556 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.2092 ORF CAL0004561 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.2093 ORF RFA1 CAL0004564 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.2093 ORF RFA1 CAL0004564 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient SLAD medium C. albicans orf19.2094 ORF PDR6 CAL0004566 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: decreased growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.2094 ORF PDR6 CAL0004566 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.2094 ORF PDR6 CAL0004566 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.2094 ORF PDR6 CAL0004566 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.2095 ORF CAL0004568 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.2097 ORF CAL0004569 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.2098 ORF ARO8 CAL0004570 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.2099 ORF HIR1 CAL0004571 PMID: 23417560|CGD_REF: CAL0000158588 homozygous diploid, classical genetics null hir1::FRT/hir1::FRT Other C. albicans viable C. albicans orf19.21 ORF CAL0000519 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.210 ORF CAL0003890 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient YPD medium C. albicans orf19.210 ORF CAL0003890 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient SLAD medium C. albicans orf19.2102 ORF CKB1 CAL0005264 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.2102 ORF CKB1 CAL0005264 PMID: 15813744|CGD_REF: CAL0104042 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.2102 ORF CKB1 CAL0005264 PMID: 23856128|CGD_REF: CAL0000172540 homozygous diploid, classical genetics null BWP17 resistance to chemicals: decreased propolis C. albicans orf19.2104 ORF CAL0005266 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.2105 ORF CAL0005267 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.2107 ORF MUQ1 CAL0005270 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.2108 ORF SOD6 CAL0005271 PMID: 18765290|CGD_REF: CAL0119430 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.2108 ORF SOD6 CAL0005271 PMID: 19019164|CGD_REF: CAL0121070 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.2108 ORF SOD6 CAL0005271 PMID: 19019164|CGD_REF: CAL0121070 homozygous diploid, classical genetics null Not recorded interaction with host/environment: normal wild-type reactive oxygen species accumulation during response to macrophages in vitro model of infection C. albicans orf19.2108 ORF SOD6 CAL0005271 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.2108 ORF SOD6 CAL0005271 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.2108 ORF SOD6 CAL0005271 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.2108 ORF SOD6 CAL0005271 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.211 ORF CAL0003891 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.2110 ORF CAL0005273 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.2112 ORF CAL0005277 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.2113 ORF CAL0005278 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.2114 ORF CAL0005280 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.2115 ORF CAL0005281 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.2115 ORF CAL0005281 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.2115 ORF CAL0005281 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.2115 ORF CAL0005281 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.2115 ORF CAL0005281 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.2116 ORF NAT2 CAL0005283 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.2116 ORF NAT2 CAL0005283 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, competitive growth (haploinsufficient phenotype assay, barcode deletion set) null SC5314 resistance to chemicals: decreased ergosterol analogs (ECC69 and/or ECC1384) C. albicans orf19.2117 ORF LEU5 CAL0005284 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.2119 ORF NDT80 CAL0005285 PMID: 20041210|CGD_REF: CAL0124764 homozygous diploid, systematic mutation set null SN152 resistance to chemicals: decreased fluconazole severely sensitive C. albicans orf19.2119 ORF NDT80 CAL0005285 PMID: 20041210|CGD_REF: CAL0124764 homozygous diploid, systematic mutation set null SN152 ionic stress resistance: decreased lithium chloride strongly sensitive C. albicans orf19.2119 ORF NDT80 CAL0005285 PMID: 20041210|CGD_REF: CAL0124764 homozygous diploid, systematic mutation set null SN152 resistance to chemicals: decreased flucytosine severely sensitive C. albicans orf19.2119 ORF NDT80 CAL0005285 PMID: 15561818|CGD_REF: CAL0082135 heterozygous diploid, classical genetics null Not recorded viable C. albicans orf19.2119 ORF NDT80 CAL0005285 PMID: 15561818|CGD_REF: CAL0082135 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.2119 ORF NDT80 CAL0005285 PMID: 20097739|CGD_REF: CAL0124922 homozygous diploid, classical genetics null ndt80::HIS1/ndt80::URA3 BWP17 hyphal growth: decreased liquid medium containing serum or N- acetylglucosamine C. albicans orf19.2119 ORF NDT80 CAL0005285 PMID: 20097739|CGD_REF: CAL0124922 homozygous diploid, classical genetics null ndt80::HIS1/ndt80::URA3 BWP17 viable C. albicans orf19.2119 ORF NDT80 CAL0005285 PMID: 20097739|CGD_REF: CAL0124922 homozygous diploid, classical genetics null ndt80::HIS1/ndt80::URA3 BWP17 cellular morphology: abnormal defects in cell separation C. albicans orf19.2119 ORF NDT80 CAL0005285 PMID: 20097739|CGD_REF: CAL0124922 homozygous diploid, classical genetics null ndt80::HIS1/ndt80::URA3 BWP17 virulence: decreased mouse intravenous infection C. albicans orf19.2119 ORF NDT80 CAL0005285 PMID: 20041210|CGD_REF: CAL0124764 homozygous diploid, systematic mutation set null SN152 resistance to chemicals: decreased sodium dodecyl sulfate strongly sensitive C. albicans orf19.2119 ORF NDT80 CAL0005285 PMID: 20041210|CGD_REF: CAL0124764 homozygous diploid, systematic mutation set null SN152 resistance to chemicals: decreased rapamycin strongly sensitive C. albicans orf19.2119 ORF NDT80 CAL0005285 PMID: 17005790|CGD_REF: CAL0116694 aneuploid, classical genetics reduction of function ndt80-R432A (mutation in DNA binding domain) Not recorded resistance to chemicals: increased fluconazole R432A allele does not restore wild-type fluconazole sensitivity in homozygous null mutant background C. albicans orf19.2119 ORF NDT80 CAL0005285 PMID: 20041210|CGD_REF: CAL0124764 homozygous diploid, systematic mutation set null SN152 invasive growth: increased SD medium at 30 deg C strongly increased C. albicans orf19.2119 ORF NDT80 CAL0005285 PMID: 15561818|CGD_REF: CAL0082135 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased voriconazole C. albicans orf19.2119 ORF NDT80 CAL0005285 PMID: 20041210|CGD_REF: CAL0124764 homozygous diploid, systematic mutation set null SN152 oxidative stress resistance: decreased hydrogen peroxide strongly sensitive C. albicans orf19.2119 ORF NDT80 CAL0005285 PMID: 20041210|CGD_REF: CAL0124764 homozygous diploid, systematic mutation set null SN152 colony appearance: abnormal Spider medium smooth colonies with almost no peripheral filamentation C. albicans orf19.2119 ORF NDT80 CAL0005285 PMID: 20041210|CGD_REF: CAL0124764 homozygous diploid, systematic mutation set null SN152 colony color: abnormal CHROMagar medium at 30 and 37 deg C darker than normal C. albicans orf19.2119 ORF NDT80 CAL0005285 PMID: 20041210|CGD_REF: CAL0124764 homozygous diploid, systematic mutation set null SN152 resistance to chemicals: decreased caffeine severely sensitive C. albicans orf19.2119 ORF NDT80 CAL0005285 PMID: 20041210|CGD_REF: CAL0124764 homozygous diploid, systematic mutation set null SN152 metal resistance: decreased copper(2+) strongly sensitive C. albicans orf19.2119 ORF NDT80 CAL0005285 PMID: 15561818|CGD_REF: CAL0082135 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased fluconazole C. albicans orf19.2119 ORF NDT80 CAL0005285 PMID: 22002580|CGD_REF: CAL0000143504 homozygous diploid, large-scale survey null SC5314 virulence: decreased mouse intravenous infection C. albicans orf19.2119 ORF NDT80 CAL0005285 PMID: 22002580|CGD_REF: CAL0000143504 homozygous diploid, large-scale survey null SC5314 hyphal growth: decreased C. albicans orf19.2119 ORF NDT80 CAL0005285 PMID: 22002580|CGD_REF: CAL0000143504 homozygous diploid, large-scale survey null SC5314 germ tube formation: decreased C. albicans orf19.2119 ORF NDT80 CAL0005285 PMID: 22265407|CGD_REF: CAL0000143925 homozygous diploid, classical genetics null Other C. albicans biofilm formation: decreased C. albicans orf19.2119 ORF NDT80 CAL0005285 PMID: 23637598|CGD_REF: CAL0000172002 homozygous diploid, classical genetics null a/alpha arg1::hisG/arg1::hisG ndt80::HIS1/ndt80::LEU2 SC5314 biofilm formation: decreased 37 degrees C in Spider medium severely reduced biofilm formation C. albicans orf19.212 ORF VPS28 CAL0003892 PMID: 17005841|CGD_REF: CAL0116696 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased Calcofluor White C. albicans orf19.212 ORF VPS28 CAL0003892 PMID: 17005841|CGD_REF: CAL0116696 homozygous diploid, classical genetics null Not recorded resistance to chemicals: normal flucytosine C. albicans orf19.212 ORF VPS28 CAL0003892 PMID: 17005841|CGD_REF: CAL0116696 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased sodium dodecyl sulfate C. albicans orf19.212 ORF VPS28 CAL0003892 PMID: 15371534|CGD_REF: CAL0082134 homozygous diploid, classical genetics null BWP17 hyphal growth: absent solid medium, alkaline pH C. albicans orf19.212 ORF VPS28 CAL0003892 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.212 ORF VPS28 CAL0003892 PMID: 15371534|CGD_REF: CAL0082134 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.212 ORF VPS28 CAL0003892 PMID: 16299290|CGD_REF: CAL0115041 homozygous diploid, classical genetics null Not recorded alkaline pH resistance: decreased C. albicans orf19.212 ORF VPS28 CAL0003892 PMID: 17005841|CGD_REF: CAL0116696 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased voriconazole C. albicans orf19.212 ORF VPS28 CAL0003892 PMID: 17005841|CGD_REF: CAL0116696 homozygous diploid, classical genetics null Not recorded resistance to chemicals: normal amphotericin B C. albicans orf19.212 ORF VPS28 CAL0003892 PMID: 16299290|CGD_REF: CAL0115041 homozygous diploid, classical genetics null Not recorded endocytosis: abnormal abnormal uptake of FM4-64 C. albicans orf19.212 ORF VPS28 CAL0003892 PMID: 17005841|CGD_REF: CAL0116696 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased micafungin C. albicans orf19.212 ORF VPS28 CAL0003892 PMID: 17005841|CGD_REF: CAL0116696 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased nikkomycin Z C. albicans orf19.212 ORF VPS28 CAL0003892 PMID: 17005841|CGD_REF: CAL0116696 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased caspofungin C. albicans orf19.212 ORF VPS28 CAL0003892 PMID: 18466294|CGD_REF: CAL0119004 homozygous diploid, classical genetics null Not recorded utilization of iron source: absent hemoglobin C. albicans orf19.212 ORF VPS28 CAL0003892 PMID: 17005841|CGD_REF: CAL0116696 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased fluconazole C. albicans orf19.212 ORF VPS28 CAL0003892 PMID: 22427429|CGD_REF: CAL0000156990 homozygous diploid, classical genetics null vps28::ARG4/vps28::URA3-dpl200 RIM8-HA::HIS1 BWP17 protein/peptide modification: absent at pH 8, Rim8-HA modification was not modified to the 95-105 kD forms in this mutant Rim8-HA C. albicans orf19.212 ORF VPS28 CAL0003892 PMID: 22427429|CGD_REF: CAL0000156990 homozygous diploid, classical genetics null BWP17 protein/peptide modification: absent mutants don't process RIM8-HA RIM8-HA C. albicans orf19.212 ORF VPS28 CAL0003892 PMID: 16299290|CGD_REF: CAL0115041 homozygous diploid, classical genetics null Not recorded virulence: decreased mouse intravenous infection C. albicans orf19.212 ORF VPS28 CAL0003892 PMID: 20581294|CGD_REF: CAL0125802 homozygous diploid, classical genetics null BWP17 alkaline pH resistance: decreased YPD pH 9, 2 days at 37 degrees C C. albicans orf19.212 ORF VPS28 CAL0003892 PMID: 20581294|CGD_REF: CAL0125802 homozygous diploid, classical genetics null BWP17 metal resistance: decreased lithium chloride (150 mM) YPD plus 150 mM lithium chloride C. albicans orf19.212 ORF VPS28 CAL0003892 PMID: 20581294|CGD_REF: CAL0125802 homozygous diploid, classical genetics null BWP17 protein/peptide modification: absent Rim101p C. albicans orf19.212 ORF VPS28 CAL0003892 PMID: 20581294|CGD_REF: CAL0125802 homozygous diploid, classical genetics null BWP17 hyphal growth: absent M199 pH 8 plates, 37 degrees C, 6 days no peripheral hyphae produced C. albicans orf19.212 ORF VPS28 CAL0003892 PMID: 20581294|CGD_REF: CAL0125802 homozygous diploid, classical genetics null BWP17 resistance to chemicals: decreased iron chelators YPD plus 150 micromolar bathophenanthrolinedisulfonic acid (BPS) C. albicans orf19.2127 ORF CST5 CAL0005308 PMID: 21249169|CGD_REF: CAL0141189 homozygous diploid, classical genetics null Other C. albicans pheromone-induced cell cycle arrest: absent alpha pheromone response assay C. albicans orf19.2127 ORF CST5 CAL0005308 PMID: 21249169|CGD_REF: CAL0141189 homozygous diploid, classical genetics null Other C. albicans viable C. albicans orf19.2127 ORF CST5 CAL0005308 PMID: 21249169|CGD_REF: CAL0141189 homozygous diploid, classical genetics null Other C. albicans shmoo formation: absent alpha pheromone response assay C. albicans orf19.2127 ORF CST5 CAL0005308 PMID: 21221248|CGD_REF: CAL0141177 homozygous diploid, classical genetics null cst5/cst5-TETp-CST5- GFP P37005 mating response: absent repressed - without doxycyclin, in response to alpha pheromone C. albicans orf19.2127 ORF CST5 CAL0005308 PMID: 21249169|CGD_REF: CAL0141189 heterozygous diploid, classical genetics overexpression Other C. albicans mating response: increased alpha pheromone response assay C. albicans orf19.2127 ORF CST5 CAL0005308 PMID: 21221248|CGD_REF: CAL0141177 homozygous diploid, classical genetics null cst5::FRT/cst5::FRT P37005 viable C. albicans orf19.2127 ORF CST5 CAL0005308 PMID: 21221248|CGD_REF: CAL0141177 homozygous diploid, classical genetics null cst5/cst5-TETp-CST5- GFP P37005 shmoo formation: absent repressed - without doxycyclin, in response to alpha pheromone C. albicans orf19.2127 ORF CST5 CAL0005308 PMID: 21221248|CGD_REF: CAL0141177 homozygous diploid, classical genetics null cst5/cst5-TETp-CST5 P37005 biofilm formation: decreased white cells; repressed - without doxycycline C. albicans orf19.213 ORF CAL0003893 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.2133 ORF LIP4 CAL0005323 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.2133 ORF LIP4 CAL0005323 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.2133 ORF LIP4 CAL0005323 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.2133 ORF LIP4 CAL0005323 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.2133 ORF LIP4 CAL0005323 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.2137 ORF CAL0005328 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.2138 ORF ILS1 CAL0005329 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.2138 ORF ILS1 CAL0005329 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 invasive growth: decreased solid SLAD media C. albicans orf19.2143 ORF CAL0005345 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.2146 ORF HAT2 CAL0005349 PMID: 23075292|CGD_REF: CAL0000158032 homozygous diploid, classical genetics null SC5314 viable C. albicans orf19.2146 ORF HAT2 CAL0005349 PMID: 23075292|CGD_REF: CAL0000158032 homozygous diploid, classical genetics null SC5314 pseudohyphal growth: increased C. albicans orf19.2146 ORF HAT2 CAL0005349 PMID: 23075292|CGD_REF: CAL0000158032 homozygous diploid, classical genetics null SC5314 resistance to chemicals: decreased methyl methanesulfonate C. albicans orf19.2146 ORF HAT2 CAL0005349 PMID: 23075292|CGD_REF: CAL0000158032 homozygous diploid, classical genetics null SC5314 resistance to chemicals: decreased ethanesulfonate C. albicans orf19.2146 ORF HAT2 CAL0005349 PMID: 23075292|CGD_REF: CAL0000158032 homozygous diploid, classical genetics null SC5314 resistance to chemicals: decreased 4-nitroquinoline N-oxide C. albicans orf19.2146 ORF HAT2 CAL0005349 PMID: 23075292|CGD_REF: CAL0000158032 homozygous diploid, classical genetics null SC5314 resistance to chemicals: decreased caspofungin C. albicans orf19.2146 ORF HAT2 CAL0005349 PMID: 23075292|CGD_REF: CAL0000158032 homozygous diploid, classical genetics null SC5314 phenotypic switching: increased C. albicans orf19.215 ORF CAL0003895 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.215 ORF CAL0003895 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.215 ORF CAL0003895 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.215 ORF CAL0003895 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.2150 ORF CAL0005361 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.2151 ORF NAG6 CAL0005364 PMID: 12076781|CGD_REF: CAL0081581 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.2151 ORF NAG6 CAL0005364 PMID: 12076781|CGD_REF: CAL0081581 homozygous diploid, classical genetics null Not recorded chemical compound accumulation: decreased hexose C. albicans orf19.2151 ORF NAG6 CAL0005364 PMID: 12076781|CGD_REF: CAL0081581 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased cycloheximide C. albicans orf19.2151 ORF NAG6 CAL0005364 PMID: 12076781|CGD_REF: CAL0081581 homozygous diploid, classical genetics null Not recorded virulence: decreased mouse intravenous infection C. albicans orf19.2151 ORF NAG6 CAL0005364 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 invasive growth: decreased solid SLAD media C. albicans orf19.2154 ORF HXK1 CAL0005368 PMID: 11298769|CGD_REF: CAL0081580 homozygous diploid, classical genetics null Not recorded utilization of carbon source: decreased GlcNAc C. albicans orf19.2154 ORF HXK1 CAL0005368 PMID: 11705974|CGD_REF: CAL0081134 homozygous diploid, classical genetics null Not recorded utilization of carbon source: decreased GlcNAc C. albicans orf19.2154 ORF HXK1 CAL0005368 PMID: 11705974|CGD_REF: CAL0081134 homozygous diploid, classical genetics null Not recorded utilization of carbon source: decreased GlcNAc C. albicans orf19.2154 ORF HXK1 CAL0005368 PMID: 11298769|CGD_REF: CAL0081580 homozygous diploid, classical genetics null Not recorded hyphal growth: decreased solid serum-containing medium C. albicans orf19.2154 ORF HXK1 CAL0005368 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.2154 ORF HXK1 CAL0005368 PMID: 11298769|CGD_REF: CAL0081580 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.2154 ORF HXK1 CAL0005368 PMID: 11705974|CGD_REF: CAL0081134 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.2154 ORF HXK1 CAL0005368 PMID: 17139615|CGD_REF: CAL0117016 homozygous diploid, classical genetics null hxk1-(nag5::HIS1/nag5::URA3, arg4) BWP17 filamentous growth: increased ex vivo model of infection (Porcine Intestinal Epithelium (PIE)-Assay) C. albicans orf19.2154 ORF HXK1 CAL0005368 PMID: 17139615|CGD_REF: CAL0117016 homozygous diploid, classical genetics null hxk1-(nag5::HIS1/nag5::URA3, arg4) BWP17 invasive growth: increased ex vivo model of infection (Porcine Intestinal Epithelium (PIE)-Assay) C. albicans orf19.2154 ORF HXK1 CAL0005368 PMID: 23341961|CGD_REF: CAL0000158485 homozygous diploid, classical genetics null CAI-4 filamentous growth: increased constitutive filamentous growth; hyperfilamentous growth under filamentation inducing conditions C. albicans orf19.2154 ORF HXK1 CAL0005368 PMID: 23341961|CGD_REF: CAL0000158485 homozygous diploid, classical genetics null CAI-4 resistance to chemicals: decreased nikkomycin Z C. albicans orf19.2156 ORF NAG1 CAL0005371 PMID: 11298769|CGD_REF: CAL0081580 homozygous diploid, classical genetics null Not recorded utilization of carbon source: absent GlcNAc C. albicans orf19.2156 ORF NAG1 CAL0005371 PMID: 11298769|CGD_REF: CAL0081580 homozygous diploid, classical genetics null Not recorded hyphal growth: decreased solid serum-containing medium C. albicans orf19.2156 ORF NAG1 CAL0005371 PMID: 11298769|CGD_REF: CAL0081580 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.2156 ORF NAG1 CAL0005371 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.2156 ORF NAG1 CAL0005371 PMID: 21700702|CGD_REF: CAL0000142437 homozygous diploid, classical genetics null BWP17 utilization of carbon source: absent GlcNAc C. albicans orf19.2156 ORF NAG1 CAL0005371 PMID: 21700702|CGD_REF: CAL0000142437 homozygous diploid, classical genetics null BWP17 hyphal growth: normal in this study, no defects in the ability of the mutant to be induced by serum were found C. albicans orf19.2156 ORF NAG1 CAL0005371 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.2156 ORF NAG1 CAL0005371 PMID: 11298769|CGD_REF: CAL0081580 homozygous diploid, classical genetics null Not recorded virulence: decreased mouse intravenous infection C. albicans orf19.2156 ORF NAG1 CAL0005371 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.2156 ORF NAG1 CAL0005371 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.2157 ORF DAC1 CAL0005372 PMID: 11298769|CGD_REF: CAL0081580 homozygous diploid, classical genetics null Not recorded utilization of carbon source: absent GlcNAc C. albicans orf19.2157 ORF DAC1 CAL0005372 PMID: 11298769|CGD_REF: CAL0081580 homozygous diploid, classical genetics null Not recorded hyphal growth: decreased solid serum-containing medium C. albicans orf19.2157 ORF DAC1 CAL0005372 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.2157 ORF DAC1 CAL0005372 PMID: 14507372|CGD_REF: CAL0088818 heterozygous diploid, large-scale survey (large-scale identification of essential genes by gene replacement and conditional expression (GRACE) method) repressible CAI-4 viable one allele is deleted and the other is placed under repressible Tet promoter C. albicans orf19.2157 ORF DAC1 CAL0005372 PMID: 11298769|CGD_REF: CAL0081580 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.2157 ORF DAC1 CAL0005372 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.2157 ORF DAC1 CAL0005372 PMID: 21700702|CGD_REF: CAL0000142437 homozygous diploid, classical genetics null BWP17 utilization of carbon source: absent GlcNAc C. albicans orf19.2157 ORF DAC1 CAL0005372 PMID: 21700702|CGD_REF: CAL0000142437 homozygous diploid, classical genetics null BWP17 hyphal growth: normal in this study, no defects in the ability of the mutant to be induced by serum were found C. albicans orf19.2157 ORF DAC1 CAL0005372 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.2157 ORF DAC1 CAL0005372 PMID: 11298769|CGD_REF: CAL0081580 homozygous diploid, classical genetics null Not recorded virulence: decreased mouse intravenous infection C. albicans orf19.2157 ORF DAC1 CAL0005372 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.2157 ORF DAC1 CAL0005372 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.2158 ORF NAG3 CAL0006619 PMID: 12076781|CGD_REF: CAL0081581 homozygous diploid, classical genetics null Not recorded utilization of carbon source: decreased GlcNAc C. albicans orf19.2158 ORF NAG3 CAL0006619 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.2158 ORF NAG3 CAL0006619 PMID: 12076781|CGD_REF: CAL0081581 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.2158 ORF NAG3 CAL0006619 PMID: 12589826|CGD_REF: CAL0081135 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.2158 ORF NAG3 CAL0006619 PMID: 12589826|CGD_REF: CAL0081135 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased 4-nitroquinoline N-oxide C. albicans orf19.2158 ORF NAG3 CAL0006619 PMID: 12076781|CGD_REF: CAL0081581 homozygous diploid, classical genetics null Not recorded chemical compound accumulation: decreased hexose C. albicans orf19.2158 ORF NAG3 CAL0006619 PMID: 12076781|CGD_REF: CAL0081581 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased cycloheximide C. albicans orf19.2158 ORF NAG3 CAL0006619 PMID: 12589826|CGD_REF: CAL0081135 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased cycloheximide C. albicans orf19.2158 ORF NAG3 CAL0006619 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, competitive growth (haploinsufficient phenotype assay, barcode deletion set) null SC5314 resistance to chemicals: decreased ergosterol analogs (ECC69 and/or ECC1384) C. albicans orf19.2158 ORF NAG3 CAL0006619 PMID: 12589826|CGD_REF: CAL0081135 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased 1,10-phenanthroline C. albicans orf19.2158 ORF NAG3 CAL0006619 PMID: 12076781|CGD_REF: CAL0081581 homozygous diploid, classical genetics null Not recorded virulence: decreased mouse intravenous infection C. albicans orf19.2158 ORF NAG3 CAL0006619 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient SC medium C. albicans orf19.2158 ORF NAG3 CAL0006619 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 invasive growth: decreased solid SLAD media C. albicans orf19.216 ORF CAL0003897 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.2160 ORF NAG4 CAL0005382 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.2160 ORF NAG4 CAL0005382 PMID: 12076781|CGD_REF: CAL0081581 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.2160 ORF NAG4 CAL0005382 PMID: 12589826|CGD_REF: CAL0081135 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.2160 ORF NAG4 CAL0005382 PMID: 12589826|CGD_REF: CAL0081135 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased 4-nitroquinoline N-oxide C. albicans orf19.2160 ORF NAG4 CAL0005382 PMID: 12076781|CGD_REF: CAL0081581 homozygous diploid, classical genetics null Not recorded chemical compound accumulation: decreased hexose C. albicans orf19.2160 ORF NAG4 CAL0005382 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, competitive growth (haploinsufficient phenotype assay, barcode deletion set) null SC5314 resistance to chemicals: decreased amphotericin B C. albicans orf19.2160 ORF NAG4 CAL0005382 PMID: 12076781|CGD_REF: CAL0081581 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased cycloheximide C. albicans orf19.2160 ORF NAG4 CAL0005382 PMID: 12589826|CGD_REF: CAL0081135 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased cycloheximide C. albicans orf19.2160 ORF NAG4 CAL0005382 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, competitive growth (haploinsufficient phenotype assay, barcode deletion set) null SC5314 resistance to chemicals: decreased ergosterol analogs (ECC69 and/or ECC1384) C. albicans orf19.2160 ORF NAG4 CAL0005382 PMID: 12589826|CGD_REF: CAL0081135 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased 1,10-phenanthroline C. albicans orf19.2160 ORF NAG4 CAL0005382 PMID: 12076781|CGD_REF: CAL0081581 homozygous diploid, classical genetics null Not recorded virulence: decreased mouse intravenous infection C. albicans orf19.2160 ORF NAG4 CAL0005382 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 invasive growth: decreased solid SLAD media C. albicans orf19.2164.1 ORF MFA1 CAF0007435 PMID: 17209123|CGD_REF: CAL0117418 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.2164.1 ORF MFA1 CAF0007435 PMID: 17209123|CGD_REF: CAL0117418 homozygous diploid, classical genetics null Not recorded mating response: abnormal C. albicans orf19.2167 ORF CAL0005395 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.217 ORF CAL0003899 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.217 ORF CAL0003899 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.217 ORF CAL0003899 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.217 ORF CAL0003899 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.2170 ORF PHM7 CAL0005406 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.2172 ORF ARA1 CAL0005411 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.2174 ORF RAD57 CAL0005415 PMID: 16607011|CGD_REF: CAL0115846 heterozygous diploid, classical genetics null SC5314 viable C. albicans orf19.2174 ORF RAD57 CAL0005415 PMID: 16607011|CGD_REF: CAL0115846 homozygous diploid, classical genetics null SC5314 inviable homozygous null mutant strain could not be recovered, suggesting that the gene is essential under the selection conditions C. albicans orf19.2174 ORF RAD57 CAL0005415 PMID: 16607011|CGD_REF: CAL0115846 heterozygous diploid, classical genetics repressible SC5314 inviable C. albicans orf19.2175 ORF CAL0005416 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.2175 ORF CAL0005416 PMID: 23620174|CGD_REF: CAL0000171941 homozygous diploid, classical genetics null CAI-4 viable C. albicans orf19.2175 ORF CAL0005416 PMID: 23620174|CGD_REF: CAL0000171941 homozygous diploid, classical genetics overexpression CAI-4 resistance to chemicals: decreased fluconazole C. albicans orf19.2175 ORF CAL0005416 PMID: 23620174|CGD_REF: CAL0000171941 homozygous diploid, classical genetics overexpression CAI-4 resistance to chemicals: decreased ketoconazole C. albicans orf19.2175 ORF CAL0005416 PMID: 23620174|CGD_REF: CAL0000171941 homozygous diploid, classical genetics overexpression CAI-4 resistance to chemicals: decreased miconazole C. albicans orf19.2175 ORF CAL0005416 PMID: 23620174|CGD_REF: CAL0000171941 homozygous diploid, classical genetics overexpression CAI-4 resistance to chemicals: decreased itraconazole C. albicans orf19.2175 ORF CAL0005416 PMID: 23620174|CGD_REF: CAL0000171941 homozygous diploid, classical genetics overexpression CAI-4 resistance to chemicals: decreased amphotericin B C. albicans orf19.2175 ORF CAL0005416 PMID: 23620174|CGD_REF: CAL0000171941 homozygous diploid, classical genetics overexpression CAI-4 resistance to chemicals: decreased terbinafine C. albicans orf19.2175 ORF CAL0005416 PMID: 23620174|CGD_REF: CAL0000171941 homozygous diploid, classical genetics null CAI-4 biofilm formation: decreased RPMI 1640 medium in microtiter plates, assayed by XTT reduction C. albicans orf19.2175 ORF CAL0005416 PMID: 23620174|CGD_REF: CAL0000171941 homozygous diploid, classical genetics overexpression CAI-4 biofilm formation: increased RPMI 1640 medium in microtiter plates, assayed by XTT reduction C. albicans orf19.2176 ORF IFM3 CAL0005418 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.2176 ORF IFM3 CAL0005418 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient YNB medium C. albicans orf19.2178 ORF MRS4 CAL0005419 PMID: 22846114|CGD_REF: CAL0000157670 homozygous diploid, classical genetics null BWP17 respiratory growth: decreased rate ethanol|glycerol C. albicans orf19.2178 ORF MRS4 CAL0005419 PMID: 22846114|CGD_REF: CAL0000157670 homozygous diploid, classical genetics null BWP17 utilization of iron source: decreased iron-limited medium (with bathophenanthroline disulfonate, BPS) C. albicans orf19.2178 ORF MRS4 CAL0005419 PMID: 22846114|CGD_REF: CAL0000157670 homozygous diploid, classical genetics null BWP17 chemical compound accumulation: increased iron cation increased cellular iron content C. albicans orf19.2178 ORF MRS4 CAL0005419 PMID: 22846114|CGD_REF: CAL0000157670 homozygous diploid, classical genetics null BWP17 metal resistance: decreased copper(2+) sulfate C. albicans orf19.2178 ORF MRS4 CAL0005419 PMID: 22846114|CGD_REF: CAL0000157670 homozygous diploid, classical genetics null BWP17 oxidative stress resistance: decreased hydrogen peroxide C. albicans orf19.2178 ORF MRS4 CAL0005419 PMID: 22846114|CGD_REF: CAL0000157670 homozygous diploid, classical genetics null BWP17 oxidative stress resistance: decreased menadione C. albicans orf19.2178 ORF MRS4 CAL0005419 PMID: 22846114|CGD_REF: CAL0000157670 homozygous diploid, classical genetics null BWP17 metal resistance: decreased cadmium dichloride C. albicans orf19.2178 ORF MRS4 CAL0005419 PMID: 22846114|CGD_REF: CAL0000157670 homozygous diploid, classical genetics null BWP17 metal resistance: decreased lithium chloride C. albicans orf19.2178 ORF MRS4 CAL0005419 PMID: 22846114|CGD_REF: CAL0000157670 homozygous diploid, classical genetics null BWP17 metal resistance: increased cobalt dichloride C. albicans orf19.2178 ORF MRS4 CAL0005419 PMID: 22846114|CGD_REF: CAL0000157670 homozygous diploid, classical genetics null BWP17 filamentous growth: decreased C. albicans orf19.2178 ORF MRS4 CAL0005419 PMID: 22846114|CGD_REF: CAL0000157670 homozygous diploid, classical genetics null BWP17 vegetative growth: decreased rate C. albicans orf19.2178 ORF MRS4 CAL0005419 PMID: 24368185|CGD_REF: CAL0000173732 homozygous diploid, classical genetics null BWP17 resistance to chemicals: decreased caspofungin C. albicans orf19.2178 ORF MRS4 CAL0005419 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 invasive growth: decreased solid SLAD media C. albicans orf19.2179 ORF SIT1 CAL0005420 PMID: 12183576|CGD_REF: CAL0081314 homozygous diploid, classical genetics null CAI-4 hyphal growth: normal various liquid and solid media C. albicans orf19.2179 ORF SIT1 CAL0005420 PMID: 12183576|CGD_REF: CAL0081314 homozygous diploid, classical genetics null Not recorded utilization of iron source: decreased decreased utilization of exogenous ferrichrome, ferricrocin, ferrichrysin, ferrirubin, coprogen, or triacetylfusarinine C siderophores, but wild-type utilization of ferrioxamines E and B, ferric citrate, or hemin C. albicans orf19.2179 ORF SIT1 CAL0005420 PMID: 12183576|CGD_REF: CAL0081314 homozygous diploid, classical genetics null Not recorded utilization of iron source: decreased decreased utilization of exogenous ferrioxamines E and B or ferric citrate C. albicans orf19.2179 ORF SIT1 CAL0005420 PMID: 12060662|CGD_REF: CAL0081313 homozygous diploid, classical genetics null Not recorded utilization of iron source: decreased defect in utilization of iron-bound ferrichrome siderophore as an iron source C. albicans orf19.2179 ORF SIT1 CAL0005420 PMID: 15616301|CGD_REF: CAL0103859 homozygous diploid, classical genetics null Not recorded utilization of iron source: decreased mutant cannot use ferrichrome as sole iron source and shows defect in uptake of ornithine-based trihydroxamate siderophoreutant cannot use ferrichrome as sole iron source and shows defect in uptake of ornithine-based trihydroxamate siderophore C. albicans orf19.2179 ORF SIT1 CAL0005420 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.2179 ORF SIT1 CAL0005420 PMID: 12060662|CGD_REF: CAL0081313 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.2179 ORF SIT1 CAL0005420 PMID: 12183576|CGD_REF: CAL0081314 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.2179 ORF SIT1 CAL0005420 PMID: 15616301|CGD_REF: CAL0103859 homozygous diploid, classical genetics null Not recorded resistance to chemicals: increased siderophore-drug conjugates C. albicans orf19.2179 ORF SIT1 CAL0005420 PMID: 12183576|CGD_REF: CAL0081314 homozygous diploid, classical genetics null Not recorded virulence: decreased human keratinocyte tissue severely decreased tissue penetration and damage ex vivo model of infection C. albicans orf19.2179 ORF SIT1 CAL0005420 PMID: 12060662|CGD_REF: CAL0081313 homozygous diploid, classical genetics null Not recorded virulence: normal mouse intravenous infection C. albicans orf19.2179 ORF SIT1 CAL0005420 PMID: 12183576|CGD_REF: CAL0081314 heterozygous diploid, classical genetics null Not recorded virulence: normal mouse intravenous infection C. albicans orf19.2179 ORF SIT1 CAL0005420 PMID: 12183576|CGD_REF: CAL0081314 homozygous diploid, classical genetics null Not recorded virulence: normal mouse intravenous infection C. albicans orf19.2179 ORF SIT1 CAL0005420 PMID: 23572557|CGD_REF: CAL0000158900 homozygous diploid, classical genetics null BWP17 adhesion: decreased Fluxion Bioflux 200, equipped with a microscope, was used for adherence analysis allowing a constant flow of cells through microfluidic channels C. albicans orf19.2179 ORF SIT1 CAL0005420 PMID: 23572557|CGD_REF: CAL0000158900 homozygous diploid, classical genetics null BWP17 resistance to chemicals: increased fluconazole RPMI+MOPS+Histidine medium , 6 hours without shaking at 37 degrees C 24 hr fluconazole treatment in 96 well plates C. albicans orf19.2179.2 ORF RPS10 CAF0006939 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient YPD medium C. albicans orf19.2179.2 ORF RPS10 CAF0006939 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient SC medium C. albicans orf19.2179.2 ORF RPS10 CAF0006939 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient YNB medium C. albicans orf19.2179.2 ORF RPS10 CAF0006939 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient SLAD medium C. albicans orf19.218 ORF BUD20 CAL0003900 PMID: 12773383|CGD_REF: CAL0087974 heterozygous diploid, classical genetics (haploinsufficient phenotype assay) null CAI-4 viable heterozygous transposon insertion C. albicans orf19.218 ORF BUD20 CAL0003900 PMID: 12773383|CGD_REF: CAL0087974 heterozygous diploid, classical genetics (haploinsufficient phenotype assay) null CAI-4 filamentous growth: increased solid Spider medium heterozygous transposon insertion C. albicans orf19.2180 ORF CAL0005439 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.2182 ORF BLM3 CAL0005443 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.2183 ORF KRE30 CAL0005445 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.2183 ORF KRE30 CAL0005445 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, competitive growth (haploinsufficient phenotype assay, barcode deletion set) null SC5314 resistance to chemicals: decreased amphotericin B C. albicans orf19.2186 ORF SEH1 CAL0005451 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.2187 ORF ALG7 CAL0005452 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.2187 ORF ALG7 CAL0005452 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, competitive growth (haploinsufficient phenotype assay, barcode deletion set) null SC5314 resistance to chemicals: decreased tunicamycin C. albicans orf19.2187 ORF ALG7 CAL0005452 PMID: 21135205|CGD_REF: CAL0139967 heterozygous diploid, large-scale survey (large-scale identification of genes essential for virulence in mouse) repressible CAI-4 virulence: absent mouse intravenous infection C. albicans orf19.2190 ORF VRP1 CAL0005470 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.2190 ORF VRP1 CAL0005470 PMID: 20656786|CGD_REF: CAL0125999 homozygous diploid, classical genetics null vrp1::ARG4/vrp1::CdHIS1|vrp1::URA3/vrp1::CdHIS1 Other C. albicans viable C. albicans orf19.2190 ORF VRP1 CAL0005470 PMID: 20656786|CGD_REF: CAL0125999 homozygous diploid, classical genetics null vrp1::ARG4/vrp1::CdHIS1|vrp1::URA3/vrp1::CdHIS1 Other C. albicans hyphal growth: decreased Spider solid media C. albicans orf19.2190 ORF VRP1 CAL0005470 PMID: 20656786|CGD_REF: CAL0125999 homozygous diploid, classical genetics null vrp1::ARG4/vrp1::CdHIS1|vrp1::URA3/vrp1::CdHIS1 Other C. albicans actin cytoskeleton morphology: abnormal C. albicans orf19.2190 ORF VRP1 CAL0005470 PMID: 20656786|CGD_REF: CAL0125999 homozygous diploid, classical genetics null vrp1::ARG4/vrp1::CdHIS1|vrp1::URA3/vrp1::CdHIS1 Other C. albicans endocytosis: decreased C. albicans orf19.2190 ORF VRP1 CAL0005470 PMID: 20656786|CGD_REF: CAL0125999 homozygous diploid, classical genetics null vrp1::ARG4/vrp1::CdHIS1|vrp1::URA3/vrp1::CdHIS1 Other C. albicans vacuolar morphology: abnormal C. albicans orf19.2192 ORF GDH2 CAL0005475 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.2193 ORF PRS5 CAL0005477 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.2194 ORF APM4 CAL0005479 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.2194 ORF APM4 CAL0005479 PMID: 24460703|CGD_REF: CAL0000173765 homozygous diploid, classical genetics null BWP17 viable C. albicans orf19.2194 ORF APM4 CAL0005479 PMID: 24460703|CGD_REF: CAL0000173765 homozygous diploid, classical genetics null BWP17 hyphal growth: decreased C. albicans orf19.2194 ORF APM4 CAL0005479 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 invasive growth: decreased solid SLAD media C. albicans orf19.2197 ORF CAL0005483 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.2198 ORF FLC3 CAL0005484 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.220 ORF PIR1 CAL0003915 PMID: 15470096|CGD_REF: CAL0082461 heterozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased Calcofluor White C. albicans orf19.220 ORF PIR1 CAL0003915 PMID: 15470096|CGD_REF: CAL0082461 heterozygous diploid, classical genetics null Not recorded vegetative growth: decreased rate minimal medium at 28 or 37 deg C C. albicans orf19.220 ORF PIR1 CAL0003915 PMID: 15470096|CGD_REF: CAL0082461 heterozygous diploid, classical genetics overexpression Not recorded viable wild-type growth and morphology C. albicans orf19.220 ORF PIR1 CAL0003915 PMID: 15470096|CGD_REF: CAL0082461 heterozygous diploid, classical genetics null Not recorded viable C. albicans orf19.220 ORF PIR1 CAL0003915 PMID: 15470096|CGD_REF: CAL0082461 heterozygous diploid, classical genetics null Not recorded cell shape: abnormal cells are elongated and misshapen, and tend to aggregate C. albicans orf19.220 ORF PIR1 CAL0003915 PMID: 15470096|CGD_REF: CAL0082461 homozygous diploid, classical genetics null Not recorded inviable homozygous null mutant strain could not be recovered, suggesting that the gene is essential under the selection conditions C. albicans orf19.220 ORF PIR1 CAL0003915 PMID: 15470096|CGD_REF: CAL0082461 heterozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased Congo Red C. albicans orf19.220 ORF PIR1 CAL0003915 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.220 ORF PIR1 CAL0003915 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.220 ORF PIR1 CAL0003915 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.220 ORF PIR1 CAL0003915 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.2200 ORF CAL0006164 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.2200 ORF CAL0006164 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.2200 ORF CAL0006164 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.2200 ORF CAL0006164 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.2200 ORF CAL0006164 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.2204.2 ORF RHO2 CAF0006942 PMID: 23796158|CGD_REF: CAL0000172432 homozygous diploid, classical genetics null BWP17 viable C. albicans orf19.2208 ORF CAL0006174 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.2209 ORF YVC1 CAL0006175 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.2209 ORF YVC1 CAL0006175 PMID: 21457451|CGD_REF: CAL0141864 homozygous diploid, classical genetics null BWP17 viable C. albicans orf19.2209 ORF YVC1 CAL0006175 PMID: 24368068|CGD_REF: CAL0000173735 homozygous diploid, classical genetics null Other C. albicans biofilm formation: decreased C. albicans orf19.2209 ORF YVC1 CAL0006175 PMID: 24368068|CGD_REF: CAL0000173735 homozygous diploid, classical genetics null Other C. albicans virulence: decreased mouse intravenous infection C. albicans orf19.2209 ORF YVC1 CAL0006175 PMID: 24368068|CGD_REF: CAL0000173735 homozygous diploid, classical genetics null Other C. albicans resistance to chemicals: decreased sodium dodecyl sulfate C. albicans orf19.2209 ORF YVC1 CAL0006175 PMID: 24368068|CGD_REF: CAL0000173735 homozygous diploid, classical genetics null Other C. albicans resistance to chemicals: decreased ethanol (8%) C. albicans orf19.2209 ORF YVC1 CAL0006175 PMID: 24368068|CGD_REF: CAL0000173735 homozygous diploid, classical genetics null Other C. albicans invasive growth: decreased C. albicans orf19.2209 ORF YVC1 CAL0006175 PMID: 24368068|CGD_REF: CAL0000173735 homozygous diploid, classical genetics null Other C. albicans flocculation: increased C. albicans orf19.2214 ORF CAL0006187 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.2215 ORF GLE1 CAL0006189 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.2216 ORF PDS5 CAL0006191 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.2222 ORF CAL0006212 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.2230 ORF CAL0006234 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.2231 ORF CAL0006237 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient YPD medium C. albicans orf19.2232 ORF RPL11 CAL0006240 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.2233 ORF PRE2 CAL0006242 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.2237 ORF SPR1 CAL0006247 PMID: 14663094|CGD_REF: CAL0080633 homozygous diploid, systematic mutation set (homozygous insertion mutants generated with URA3-ARG4-URA3 (UAU1) cassette) null BWP17 viable C. albicans orf19.2237 ORF SPR1 CAL0006247 PMID: 18765290|CGD_REF: CAL0119430 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.2237 ORF SPR1 CAL0006247 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.2237 ORF SPR1 CAL0006247 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.2237 ORF SPR1 CAL0006247 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.2237 ORF SPR1 CAL0006247 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.2241 ORF PST1 CAL0006260 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.2242 ORF PRB1 CAL0006263 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.2242 ORF PRB1 CAL0006263 PMID: 12455710|CGD_REF: CAL0081754 heterozygous diploid, classical genetics null Not recorded viable no apparent phenotype C. albicans orf19.2242 ORF PRB1 CAL0006263 PMID: 12455710|CGD_REF: CAL0081754 homozygous diploid, classical genetics null Not recorded viable no apparent phenotype C. albicans orf19.2245 ORF YPT72 CAL0006268 PMID: 19364843|CGD_REF: CAL0122751 homozygous diploid, classical genetics null Not recorded starvation resistance: decreased nitrogen starvation C. albicans orf19.2245 ORF YPT72 CAL0006268 PMID: 19364843|CGD_REF: CAL0122751 homozygous diploid, classical genetics null Not recorded vacuolar morphology: abnormal vacuoles are fragmented C. albicans orf19.2245 ORF YPT72 CAL0006268 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.2245 ORF YPT72 CAL0006268 PMID: 19364843|CGD_REF: CAL0122751 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.2245 ORF YPT72 CAL0006268 PMID: 19364843|CGD_REF: CAL0122751 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased rapamycin C. albicans orf19.2245 ORF YPT72 CAL0006268 PMID: 19364843|CGD_REF: CAL0122751 homozygous diploid, classical genetics null Not recorded endocytosis: abnormal FM4-64 is internalized to multiple compartments C. albicans orf19.2245 ORF YPT72 CAL0006268 PMID: 19364843|CGD_REF: CAL0122751 homozygous diploid, classical genetics null CAI-4 filamentous growth: decreased C. albicans orf19.2245 ORF YPT72 CAL0006268 PMID: 19364843|CGD_REF: CAL0122751 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased caffeine C. albicans orf19.2245 ORF YPT72 CAL0006268 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.2245 ORF YPT72 CAL0006268 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: abnormal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.2245 ORF YPT72 CAL0006268 PMID: 19364843|CGD_REF: CAL0122751 homozygous diploid, classical genetics null Not recorded virulence: decreased mouse intravenous infection C. albicans orf19.2245 ORF YPT72 CAL0006268 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.2245 ORF YPT72 CAL0006268 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.2246 ORF CAL0006270 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.2248 ORF ARE2 CAL0006272 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.2249 ORF CAL0006273 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.2250 ORF SPE3 CAL0006284 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.2251 ORF AAH1 CAL0006286 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.2251 ORF AAH1 CAL0006286 PMID: 14663094|CGD_REF: CAL0080633 homozygous diploid, systematic mutation set (homozygous insertion mutants generated with URA3-ARG4-URA3 (UAU1) cassette) null BWP17 viable C. albicans orf19.2251 ORF AAH1 CAL0006286 PMID: 23572557|CGD_REF: CAL0000158900 homozygous diploid, classical genetics null BWP17 adhesion: decreased Fluxion Bioflux 200, equipped with a microscope, was used for adherence analysis allowing a constant flow of cells through microfluidic channels C. albicans orf19.2251 ORF AAH1 CAL0006286 PMID: 23572557|CGD_REF: CAL0000158900 homozygous diploid, classical genetics null BWP17 resistance to chemicals: increased fluconazole RPMI+MOPS+Histidine medium , 6 hours without shaking at 37 degrees C 24 hr fluconazole treatment in 96 well plates C. albicans orf19.2260 ORF CAL0006308 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.2260 ORF CAL0006308 PMID: 15964282|CGD_REF: CAL0114274 homozygous diploid, systematic mutation set (split-marker transposon insertion strategy to disrupt both alleles) null BWP17 viable C. albicans orf19.2260 ORF CAL0006308 PMID: 15964282|CGD_REF: CAL0114274 homozygous diploid, systematic mutation set (split-marker transposon insertion strategy to disrupt both alleles) null BWP17 biofilm formation: normal C. albicans orf19.2261 ORF CAL0006311 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.2262 ORF CAL0006314 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.2264 ORF OLE2 CAL0006318 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.2264 ORF OLE2 CAL0006318 PMID: 15184585|CGD_REF: CAL0081531 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.2264 ORF OLE2 CAL0006318 PMID: 17470538|CGD_REF: CAL0118025 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.2264 ORF OLE2 CAL0006318 PMID: 17470538|CGD_REF: CAL0118025 homozygous diploid, classical genetics null Not recorded chemical compound accumulation: decreased prostaglandin E2 C. albicans orf19.2265 ORF CAL0006320 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.2265 ORF CAL0006320 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.2265 ORF CAL0006320 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.2265 ORF CAL0006320 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.2267 ORF RFA2 CAL0006323 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.2268 ORF RCK2 CAL0006324 PMID: 18625027|CGD_REF: CAL0119338 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased lithium chloride C. albicans orf19.2268 ORF RCK2 CAL0006324 PMID: 18625027|CGD_REF: CAL0119338 homozygous diploid, classical genetics null Not recorded vegetative growth: decreased rate C. albicans orf19.2268 ORF RCK2 CAL0006324 PMID: 18625027|CGD_REF: CAL0119338 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.2268 ORF RCK2 CAL0006324 PMID: 18625027|CGD_REF: CAL0119338 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased rapamycin C. albicans orf19.2268 ORF RCK2 CAL0006324 PMID: 18625027|CGD_REF: CAL0119338 homozygous diploid, classical genetics null Not recorded ionic stress resistance: decreased sodium chloride C. albicans orf19.2268 ORF RCK2 CAL0006324 PMID: 20402792|CGD_REF: CAL0125387 homozygous diploid, classical genetics null rck2∷hisG/rck2∷hisG RM1000 resistance to chemicals: decreased sodium dodecyl sulfate (0.04%) C. albicans orf19.2268 ORF RCK2 CAL0006324 PMID: 20402792|CGD_REF: CAL0125387 homozygous diploid, classical genetics null rck2∷hisG/rck2∷hisG RM1000 resistance to chemicals: decreased Congo Red (0.3 mg/ml) C. albicans orf19.2268 ORF RCK2 CAL0006324 PMID: 20402792|CGD_REF: CAL0125387 homozygous diploid, classical genetics null rck2∷hisG/rck2∷hisG RM1000 resistance to chemicals: decreased Calcofluor White (0.15 mg/ml) C. albicans orf19.2268 ORF RCK2 CAL0006324 PMID: 20402792|CGD_REF: CAL0125387 homozygous diploid, classical genetics null rck2∷hisG/rck2∷hisG RM1000 filamentous growth: decreased reduced filamentation in liquid Spider, YPD plus 10% FBS or Lee's media C. albicans orf19.2268 ORF RCK2 CAL0006324 PMID: 20402792|CGD_REF: CAL0125387 homozygous diploid, classical genetics null rck2∷hisG/rck2∷hisG RM1000 heat sensitivity: increased elevated temperatures (37 and 42 deg) C. albicans orf19.2268 ORF RCK2 CAL0006324 PMID: 20402792|CGD_REF: CAL0125387 homozygous diploid, classical genetics null rck2∷hisG/rck2∷hisG RM1000 virulence: decreased mouse intravenous infection C. albicans orf19.2268 ORF RCK2 CAL0006324 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 invasive growth: decreased solid SLAD media C. albicans orf19.2269 ORF CAL0006325 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.2270 ORF SMF12 CAL0006336 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.2270 ORF SMF12 CAL0006336 PMID: 14663094|CGD_REF: CAL0080633 homozygous diploid, systematic mutation set (homozygous insertion mutants generated with URA3-ARG4-URA3 (UAU1) cassette) null BWP17 viable C. albicans orf19.2272 ORF AFT2 CAL0006340 PMID: 23626810|CGD_REF: CAL0000172006 homozygous diploid, classical genetics null BWP17 chemical compound excretion: decreased iron cation ion-deficient conditions C. albicans orf19.2272 ORF AFT2 CAL0006340 PMID: 23626810|CGD_REF: CAL0000172006 homozygous diploid, classical genetics null BWP17 oxidative stress resistance: decreased hydrogen peroxide C. albicans orf19.2272 ORF AFT2 CAL0006340 PMID: 23626810|CGD_REF: CAL0000172006 homozygous diploid, classical genetics null BWP17 filamentous growth: decreased solid Spider medium, 5 days incubation at 37 deg C. albicans orf19.2272 ORF AFT2 CAL0006340 PMID: 23626810|CGD_REF: CAL0000172006 homozygous diploid, classical genetics null BWP17 flocculation: increased C. albicans orf19.2272 ORF AFT2 CAL0006340 PMID: 23626810|CGD_REF: CAL0000172006 homozygous diploid, classical genetics null BWP17 adhesion: increased C. albicans orf19.2272 ORF AFT2 CAL0006340 PMID: 23626810|CGD_REF: CAL0000172006 homozygous diploid, classical genetics null BWP17 hyphal growth: increased liquid YPD+10% serum and Spider medium at 37 deg C. albicans orf19.2272 ORF AFT2 CAL0006340 PMID: 20595261|CGD_REF: CAL0125818 homozygous diploid, classical genetics null BWP17 filamentous growth: decreased Spider or YPG plus 10% serum medium, 37 degrees C, 4 days C. albicans orf19.2272 ORF AFT2 CAL0006340 PMID: 20595261|CGD_REF: CAL0125818 homozygous diploid, classical genetics null BWP17 viable C. albicans orf19.2272 ORF AFT2 CAL0006340 PMID: 20595261|CGD_REF: CAL0125818 homozygous diploid, classical genetics null BWP17 protein activity: decreased M199 medium buffered at pH4 or pH 8, but not at pH 4 with 50 micromolar bathophenanthroline disulfondisulfonate (BPS) ferric reductase C. albicans orf19.2272 ORF AFT2 CAL0006340 PMID: 20595261|CGD_REF: CAL0125818 homozygous diploid, classical genetics null BWP17 virulence: decreased mouse intravenous infection C. albicans orf19.2275 ORF CAL0006345 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.2276 ORF CAL0006347 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.2277 ORF TPK2 CAL0006348 PMID: 12553943|CGD_REF: CAL0081980 homozygous diploid, classical genetics null Not recorded germ tube formation: decreased GlcNAc-containing medium defect is also observed in medium with low concentrations of serum, but not at high serum concentrations C. albicans orf19.2277 ORF TPK2 CAL0006348 PMID: 15760450|CGD_REF: CAL0104038 homozygous diploid, classical genetics null CAI-4 hyphal growth: abnormal FaDu or OKF6/TERT-2 epithelial cells hyphae are short in vitro model of infection C. albicans orf19.2277 ORF TPK2 CAL0006348 PMID: 15760450|CGD_REF: CAL0104038 heterozygous diploid, classical genetics null CAI-4 hyphal growth: normal FaDu or OKF6/TERT-2 epithelial cells reintegrant in vitro model of infection C. albicans orf19.2277 ORF TPK2 CAL0006348 PMID: 11886556|CGD_REF: CAL0081621 heterozygous diploid, classical genetics overexpression Not recorded hyphal growth: abnormal hyphal growth occurs in non-inducing SCAA medium C. albicans orf19.2277 ORF TPK2 CAL0006348 PMID: 11886556|CGD_REF: CAL0081621 homozygous diploid, classical genetics null Not recorded hyphal growth: decreased liquid serum-containing or Spider media C. albicans orf19.2277 ORF TPK2 CAL0006348 PMID: 14507372|CGD_REF: CAL0088818 heterozygous diploid, large-scale survey (large-scale identification of essential genes by gene replacement and conditional expression (GRACE) method) repressible CAI-4 viable one allele is deleted and the other is placed under repressible Tet promoter C. albicans orf19.2277 ORF TPK2 CAL0006348 PMID: 11886556|CGD_REF: CAL0081621 homozygous diploid, classical genetics null Not recorded viable no apparent phenotype C. albicans orf19.2277 ORF TPK2 CAL0006348 PMID: 12553943|CGD_REF: CAL0081980 homozygous diploid, classical genetics null Not recorded viable YEPD or minimal media wild-type growth rate C. albicans orf19.2277 ORF TPK2 CAL0006348 PMID: 12553943|CGD_REF: CAL0081980 heterozygous diploid, classical genetics null Not recorded viable C. albicans orf19.2277 ORF TPK2 CAL0006348 PMID: 16407097|CGD_REF: CAL0115390 homozygous diploid, classical genetics null Not recorded apoptosis: normal C. albicans orf19.2277 ORF TPK2 CAL0006348 PMID: 10652099|CGD_REF: CAL0080974 homozygous diploid, classical genetics overexpression tpk2::hisG/tpk2::hisG-URA3-hisG CAI-4 filamentous growth: increased increased filamentation and invasive growth C. albicans orf19.2277 ORF TPK2 CAL0006348 PMID: 10652099|CGD_REF: CAL0080974 homozygous diploid, classical genetics null tpk2::hisG/tpk2::hisG-URA3-hisG CAI-4 hyphal growth: abnormal Spider medium delayed hyphal development C. albicans orf19.2277 ORF TPK2 CAL0006348 PMID: 10652099|CGD_REF: CAL0080974 homozygous diploid, classical genetics overexpression tpk2::hisG/tpk2::hisG-URA3-hisG CAI-4 invasive growth: increased increased filamentation and invasive growth C. albicans orf19.2277 ORF TPK2 CAL0006348 PMID: 10652099|CGD_REF: CAL0080974 homozygous diploid, classical genetics null tpk2::hisG/tpk2::hisG-URA3-hisG CAI-4 virulence: decreased partial reduction of virulence mouse intravenous infection C. albicans orf19.2277 ORF TPK2 CAL0006348 PMID: 21407800|CGD_REF: CAL0141800 homozygous diploid, classical genetics null BWP17 interaction with host/environment: abnormal significantly reduces adhesion, invasion, and damage to epithelial cells ex vivo model of infection C. albicans orf19.2277 ORF TPK2 CAL0006348 PMID: 21456055|CGD_REF: CAL0141857 homozygous diploid, classical genetics null tpk2::Cat/tpk2::Cat CAI-4 biofilm formation: decreased C. albicans orf19.2277 ORF TPK2 CAL0006348 PMID: 21456055|CGD_REF: CAL0141857 homozygous diploid, classical genetics null tpk2::Cat/tpk2::Cat CAI-4 flocculation: decreased C. albicans orf19.2277 ORF TPK2 CAL0006348 PMID: 15760450|CGD_REF: CAL0104038 homozygous diploid, classical genetics null Not recorded virulence: decreased FaDu or OKF6/TERT-2 epithelial cells decreased capacity to damage cells in vitro model of infection C. albicans orf19.2277 ORF TPK2 CAL0006348 PMID: 15760450|CGD_REF: CAL0104038 heterozygous diploid, classical genetics null Not recorded virulence: normal mouse intravenous infection C. albicans orf19.2277 ORF TPK2 CAL0006348 PMID: 15760450|CGD_REF: CAL0104038 homozygous diploid, classical genetics null Not recorded virulence: normal mouse intravenous infection C. albicans orf19.2277 ORF TPK2 CAL0006348 PMID: 15760450|CGD_REF: CAL0104038 homozygous diploid, classical genetics null Not recorded virulence: decreased mouse oropharyngeal infection C. albicans orf19.2277 ORF TPK2 CAL0006348 PMID: 15760450|CGD_REF: CAL0104038 heterozygous diploid, classical genetics null Not recorded virulence: normal mouse oropharyngeal infection C. albicans orf19.2277 ORF TPK2 CAL0006348 PMID: 22923045|CGD_REF: CAL0000157829 homozygous diploid, competitive growth null Other C. albicans formation of anatomical structure: absent elevated concentrations of CO2 at 37 deg finger structure C. albicans orf19.2277 ORF TPK2 CAL0006348 PMID: 21234881|CGD_REF: CAL0141183 homozygous diploid, classical genetics null tpk2::Cat/tpk2::Cat CAI-4 biofilm formation: decreased C. albicans orf19.2280 ORF ZCF10 CAL0006370 PMID: 15964282|CGD_REF: CAL0114274 homozygous diploid, systematic mutation set (split-marker transposon insertion strategy to disrupt both alleles) null BWP17 viable C. albicans orf19.2280 ORF ZCF10 CAL0006370 PMID: 15964282|CGD_REF: CAL0114274 homozygous diploid, systematic mutation set (split-marker transposon insertion strategy to disrupt both alleles) null BWP17 biofilm formation: normal C. albicans orf19.2280 ORF ZCF10 CAL0006370 PMID: 22073120|CGD_REF: CAL0000143592 homozygous diploid, classical genetics null BWP17 viable C. albicans orf19.2280 ORF ZCF10 CAL0006370 PMID: 22073120|CGD_REF: CAL0000143592 homozygous diploid, classical genetics null BWP17 colony appearance: abnormal decreased colony wrinkling C. albicans orf19.2280 ORF ZCF10 CAL0006370 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 invasive growth: decreased solid SLAD media C. albicans orf19.2281 ORF CAL0006372 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.2281 ORF CAL0006372 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.2281 ORF CAL0006372 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.2281 ORF CAL0006372 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.2281 ORF CAL0006372 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.2282 ORF CAL0006375 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.2282 ORF CAL0006375 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.2282 ORF CAL0006375 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.2282 ORF CAL0006375 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.2282 ORF CAL0006375 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.2283 ORF DQD1 CAL0006377 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.2284 ORF CAL0006378 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.2284 ORF CAL0006378 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.2284 ORF CAL0006378 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.2284 ORF CAL0006378 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.2284 ORF CAL0006378 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.2285 ORF CAL0006380 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, competitive growth (haploinsufficient phenotype assay, barcode deletion set) null SC5314 resistance to chemicals: decreased 5-fluorouracil C. albicans orf19.2285 ORF CAL0006380 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.2286 ORF CAL0006381 PMID: 21414038|CGD_REF: CAL0141808 homozygous diploid, classical genetics null BWP17 viable C. albicans orf19.2287 ORF RPA12 CAL0006382 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.2288 ORF CCT5 CAL0006383 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.2289 ORF ARP3 CAL0006384 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.2289 ORF ARP3 CAL0006384 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, competitive growth (haploinsufficient phenotype assay, barcode deletion set) null SC5314 resistance to chemicals: decreased cytochalasin D C. albicans orf19.229 ORF CAL0003934 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 invasive growth: decreased solid SLAD media C. albicans orf19.2290 ORF TOR1 CAL0006402 PMID: 19115836|CGD_REF: CAL0122036 heterozygous diploid, competitive growth (haploinsufficient phenotype assay, barcode deletion set) null SC5314 resistance to chemicals: decreased rapamycin C. albicans orf19.2290 ORF TOR1 CAL0006402 PMID: 11600372|CGD_REF: CAL0081772 heterozygous diploid, classical genetics null TOR1-1/TOR1 Not recorded resistance to chemicals: increased rapamycin C. albicans orf19.2290 ORF TOR1 CAL0006402 PMID: 11600372|CGD_REF: CAL0081772 heterozygous diploid, classical genetics null TOR1-1/TOR1 Not recorded viable C. albicans orf19.2290 ORF TOR1 CAL0006402 PMID: 11600372|CGD_REF: CAL0081772 heterozygous diploid, classical genetics null TOR1-2/TOR1 Not recorded resistance to chemicals: increased rapamycin C. albicans orf19.2290 ORF TOR1 CAL0006402 PMID: 11600372|CGD_REF: CAL0081772 heterozygous diploid, classical genetics null TOR1-2/TOR1 Not recorded viable C. albicans orf19.2297 ORF ARL3 CAL0006416 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.2297 ORF ARL3 CAL0006416 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.2297 ORF ARL3 CAL0006416 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.2297 ORF ARL3 CAL0006416 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.2297 ORF ARL3 CAL0006416 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.2298 ORF WBP1 CAL0006417 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.23 ORF RTA3 CAL0000521 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.230 ORF CAL0003947 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient YPD medium C. albicans orf19.230 ORF CAL0003947 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient YNB medium C. albicans orf19.230 ORF CAL0003947 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient SLAD medium C. albicans orf19.2302 ORF CAL0000642 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.2302 ORF CAL0000642 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.2302 ORF CAL0000642 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.2302 ORF CAL0000642 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.2302 ORF CAL0000642 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.2303 ORF FGR16 CAL0000644 PMID: 12773383|CGD_REF: CAL0087974 heterozygous diploid, classical genetics (haploinsufficient phenotype assay) unspecified CAI-4 filamentous growth: increased solid Spider medium or solid YEPD plus serum increase is allele- and medium-dependent; transposon insertion proximal to, but not within, the ORF C. albicans orf19.2304 ORF CAL0000646 PMID: 12773383|CGD_REF: CAL0087974 heterozygous diploid, classical genetics (haploinsufficient phenotype assay) unspecified CAI-4 filamentous growth: increased solid Spider medium or solid YEPD plus serum increase is allele- and medium-dependent; transposon insertion proximal to, but not within, the ORF C. albicans orf19.2306 ORF CAL0000649 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.2307 ORF CAL0000650 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.2307 ORF CAL0000650 PMID: 21135205|CGD_REF: CAL0139967 heterozygous diploid, large-scale survey (large-scale identification of genes essential for virulence in mouse) repressible CAI-4 virulence: absent mouse intravenous infection C. albicans orf19.2309 ORF PET127 CAL0000652 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.231 ORF APL2 CAL0003949 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.231 ORF APL2 CAL0003949 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, competitive growth (haploinsufficient phenotype assay, barcode deletion set) null SC5314 resistance to chemicals: decreased ergosterol analogs (ECC69 and/or ECC1384) C. albicans orf19.2312 ORF CAL0000668 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.2312 ORF CAL0000668 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.2312 ORF CAL0000668 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.2312 ORF CAL0000668 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.2312 ORF CAL0000668 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.2313 ORF CAL0000670 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.2313 ORF CAL0000670 PMID: 21135205|CGD_REF: CAL0139967 heterozygous diploid, competitive growth (large-scale identification of genes essential for virulence in mouse) repressible CAI-4 virulence: normal mouse intravenous infection C. albicans orf19.2314 ORF CAL0000672 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, competitive growth (haploinsufficient phenotype assay, barcode deletion set) null SC5314 resistance to chemicals: decreased 5-fluorouracil C. albicans orf19.2314 ORF CAL0000672 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, competitive growth (haploinsufficient phenotype assay, barcode deletion set) null SC5314 resistance to chemicals: decreased tubercidin C. albicans orf19.2314 ORF CAL0000672 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, competitive growth (haploinsufficient phenotype assay, barcode deletion set) null SC5314 resistance to chemicals: decreased flucytosine C. albicans orf19.2314 ORF CAL0000672 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.2315 ORF RTG3 CAL0000674 PMID: 17555439|CGD_REF: CAL0117968 homozygous diploid, classical genetics null Not recorded survival rate in stationary phase: decreased C. albicans orf19.2315 ORF RTG3 CAL0000674 PMID: 15964282|CGD_REF: CAL0114274 homozygous diploid, systematic mutation set (split-marker transposon insertion strategy to disrupt both alleles) null BWP17 viable C. albicans orf19.2315 ORF RTG3 CAL0000674 PMID: 15964282|CGD_REF: CAL0114274 homozygous diploid, systematic mutation set (split-marker transposon insertion strategy to disrupt both alleles) null BWP17 biofilm formation: normal C. albicans orf19.2315 ORF RTG3 CAL0000674 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: decreased growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.2315 ORF RTG3 CAL0000674 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.2315 ORF RTG3 CAL0000674 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.2315 ORF RTG3 CAL0000674 PMID: 23526879|CGD_REF: CAL0000158852 homozygous diploid, classical genetics null SN152 virulence: decreased mouse intravenous infection C. albicans orf19.2315 ORF RTG3 CAL0000674 PMID: 23526879|CGD_REF: CAL0000158852 homozygous diploid, classical genetics null SN152 viable C. albicans orf19.2315 ORF RTG3 CAL0000674 PMID: 23526879|CGD_REF: CAL0000158852 homozygous diploid, classical genetics null SN152 virulence: decreased significant defect in GI tract colonization mouse gastrointestinal tract infection C. albicans orf19.2315 ORF RTG3 CAL0000674 PMID: 24606409|CGD_REF: CAL0000173789 homozygous diploid, classical genetics null BWP17 resistance to chemicals: decreased sodium(1+) C. albicans orf19.2315 ORF RTG3 CAL0000674 PMID: 24606409|CGD_REF: CAL0000173789 homozygous diploid, classical genetics null BWP17 resistance to chemicals: decreased calcium(2+) C. albicans orf19.2315 ORF RTG3 CAL0000674 PMID: 24606409|CGD_REF: CAL0000173789 homozygous diploid, classical genetics null BWP17 resistance to chemicals: decreased sodium dodecyl sulfate C. albicans orf19.2315 ORF RTG3 CAL0000674 PMID: 24606409|CGD_REF: CAL0000173789 homozygous diploid, classical genetics null BWP17 resistance to chemicals: decreased fluconazole C. albicans orf19.2315 ORF RTG3 CAL0000674 PMID: 24606409|CGD_REF: CAL0000173789 homozygous diploid, classical genetics null BWP17 resistance to chemicals: decreased ketoconazole C. albicans orf19.2315 ORF RTG3 CAL0000674 PMID: 24606409|CGD_REF: CAL0000173789 homozygous diploid, classical genetics null BWP17 filamentous growth: decreased liquid YPD medium containing 10% FBS at 37 deg C. albicans orf19.2315 ORF RTG3 CAL0000674 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.2319 ORF CAL0000677 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.232 ORF CAL0003950 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.2324 ORF UBA4 CAL0000697 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.2325 ORF CAL0000698 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.2330 ORF CAL0000714 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.2330 ORF CAL0000714 PMID: 21135205|CGD_REF: CAL0139967 heterozygous diploid, large-scale survey (large-scale identification of genes essential for virulence in mouse) repressible CAI-4 virulence: absent mouse intravenous infection C. albicans orf19.2331 ORF ADA2 CAL0000716 PMID: 19666778|CGD_REF: CAL0123941 homozygous diploid, classical genetics null BWP17 hyphal growth: absent Spider medium at 37 deg C, or in vivo in a C. elegans model C. albicans orf19.2331 ORF ADA2 CAL0000716 PMID: 15964282|CGD_REF: CAL0114274 homozygous diploid, systematic mutation set (split-marker transposon insertion strategy to disrupt both alleles) null BWP17 viable C. albicans orf19.2331 ORF ADA2 CAL0000716 PMID: 16552442|CGD_REF: CAL0115731 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.2331 ORF ADA2 CAL0000716 PMID: 15964282|CGD_REF: CAL0114274 homozygous diploid, systematic mutation set (split-marker transposon insertion strategy to disrupt both alleles) null BWP17 biofilm formation: normal C. albicans orf19.2331 ORF ADA2 CAL0000716 PMID: 19279142|CGD_REF: CAL0122493 homozygous diploid, classical genetics null Not recorded oxidative stress resistance: decreased hydrogen peroxide C. albicans orf19.2331 ORF ADA2 CAL0000716 PMID: 16552442|CGD_REF: CAL0115731 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased caspofungin C. albicans orf19.2331 ORF ADA2 CAL0000716 PMID: 19279142|CGD_REF: CAL0122493 homozygous diploid, classical genetics null Not recorded oxidative stress resistance: decreased menadione C. albicans orf19.2331 ORF ADA2 CAL0000716 PMID: 16552442|CGD_REF: CAL0115731 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased Congo Red C. albicans orf19.2331 ORF ADA2 CAL0000716 PMID: 19279142|CGD_REF: CAL0122493 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased fluconazole C. albicans orf19.2331 ORF ADA2 CAL0000716 PMID: 22359502|CGD_REF: CAL0000144048 homozygous diploid, classical genetics null BWP17 viable insertion mutant, independent BWP17 deletion mutant and complemented strains also tested C. albicans orf19.2331 ORF ADA2 CAL0000716 PMID: 22359502|CGD_REF: CAL0000144048 homozygous diploid, classical genetics null BWP17 adhesion: decreased insertion mutant, independent BWP17 deletion mutant and complemented strains also tested C. albicans orf19.2334 ORF BIG1 CAL0000722 PMID: 16552067|CGD_REF: CAL0115741 homozygous diploid, classical genetics null CAI-4 hyphal growth: abnormal shorter hyphae, but normal yeast-to-hyphae transition C. albicans orf19.2334 ORF BIG1 CAL0000722 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.2334 ORF BIG1 CAL0000722 PMID: 16552067|CGD_REF: CAL0115741 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.2334 ORF BIG1 CAL0000722 PMID: 16552067|CGD_REF: CAL0115741 homozygous diploid, classical genetics null Not recorded adhesion: decreased adhesion to human epithelial (HeLa) cells C. albicans orf19.2334 ORF BIG1 CAL0000722 PMID: 16552067|CGD_REF: CAL0115741 homozygous diploid, classical genetics null Not recorded cell shape: abnormal cells are elongated and tend to aggregate C. albicans orf19.2334 ORF BIG1 CAL0000722 PMID: 16552067|CGD_REF: CAL0115741 homozygous diploid, classical genetics null Not recorded chitin deposition: increased increased cell wall chitin C. albicans orf19.2334 ORF BIG1 CAL0000722 PMID: 16552067|CGD_REF: CAL0115741 homozygous diploid, classical genetics null Not recorded chlamydospore formation: absent C. albicans orf19.2334 ORF BIG1 CAL0000722 PMID: 16552067|CGD_REF: CAL0115741 homozygous diploid, classical genetics null Not recorded chemical compound accumulation: decreased (1->6)-beta-D-glucan decreased cell wall beta-1,6-glucan C. albicans orf19.2334 ORF BIG1 CAL0000722 PMID: 16552067|CGD_REF: CAL0115741 homozygous diploid, classical genetics null Not recorded virulence: decreased mouse intravenous infection C. albicans orf19.2335 ORF CAL0000724 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, competitive growth (haploinsufficient phenotype assay, barcode deletion set) null SC5314 resistance to chemicals: decreased 5-fluorouracil C. albicans orf19.2335 ORF CAL0000724 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.2336 ORF CAL0000726 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.2336 ORF CAL0000726 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.2336 ORF CAL0000726 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.2336 ORF CAL0000726 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.2337 ORF ALP1 CAL0000727 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.2337 ORF ALP1 CAL0000727 PMID: 21414038|CGD_REF: CAL0141808 homozygous diploid, classical genetics null BWP17 viable C. albicans orf19.2337 ORF ALP1 CAL0000727 PMID: 21414038|CGD_REF: CAL0141808 homozygous diploid, classical genetics null BWP17 biofilm formation: normal C. albicans orf19.2337 ORF ALP1 CAL0000727 PMID: 21507960|CGD_REF: CAL0141910 homozygous diploid, classical genetics null alp1/alp1(cyn1::FRT/cyn1::FRT) SC5314 utilization of sulfur source: decreased cystine C. albicans orf19.234 ORF PHA2 CAL0003953 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.2340 ORF CDC48 CAL0000732 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.2341 ORF HNT1 CAL0000734 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.2342 ORF SFT2 CAL0000736 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.2343 ORF VPS23 CAL0000738 PMID: 15371534|CGD_REF: CAL0082134 homozygous diploid, classical genetics null BWP17 hyphal growth: absent solid medium, alkaline pH C. albicans orf19.2343 ORF VPS23 CAL0000738 PMID: 15371534|CGD_REF: CAL0082134 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.2343 ORF VPS23 CAL0000738 PMID: 18466294|CGD_REF: CAL0119004 homozygous diploid, classical genetics null Not recorded utilization of iron source: absent hemoglobin C. albicans orf19.2346 ORF CAL0000742 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.2347 ORF MNN2 CAL0000743 PMID: 16467465|CGD_REF: CAL0115507 homozygous diploid, classical genetics null Not recorded resistance to enzymatic treatment: decreased glucanase C. albicans orf19.2347 ORF MNN2 CAL0000743 PMID: 16467465|CGD_REF: CAL0115507 homozygous diploid, classical genetics null Not recorded toxin resistance: increased lactoferrin C. albicans orf19.2347 ORF MNN2 CAL0000743 PMID: 16467465|CGD_REF: CAL0115507 homozygous diploid, classical genetics null CAI-4 hyphal growth: decreased solid media C. albicans orf19.2347 ORF MNN2 CAL0000743 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.2347 ORF MNN2 CAL0000743 PMID: 16467465|CGD_REF: CAL0115507 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.2347 ORF MNN2 CAL0000743 PMID: 12773383|CGD_REF: CAL0087974 heterozygous diploid, classical genetics (haploinsufficient phenotype assay) unspecified CAI-4 filamentous growth: decreased solid Spider medium transposon insertion proximal to, but not within, the ORF C. albicans orf19.2347 ORF MNN2 CAL0000743 PMID: 16467465|CGD_REF: CAL0115507 homozygous diploid, classical genetics null Not recorded virulence: decreased mouse intravenous infection C. albicans orf19.2347 ORF MNN2 CAL0000743 PMID: 23633946|CGD_REF: CAL0000172007 homozygous diploid, classical genetics null mnn2::dpl200/mnn2::dpl200 CAI-4 chemical compound accumulation: increased glucan C. albicans orf19.2347 ORF MNN2 CAL0000743 PMID: 23633946|CGD_REF: CAL0000172007 homozygous diploid, classical genetics null CAI-4 resistance to chemicals: decreased Calcofluor White YPD agar plates containing 100 ug/ml CFW C. albicans orf19.2347 ORF MNN2 CAL0000743 PMID: 23633946|CGD_REF: CAL0000172007 homozygous diploid, classical genetics null mnn2::dpl200/mnn2::dpl200 CAI-4 virulence: decreased mutant allow increased survival time of larvae other model (G. mellonella larvae) C. albicans orf19.2347 ORF MNN2 CAL0000743 PMID: 23633946|CGD_REF: CAL0000172007 homozygous diploid, classical genetics null mnn2::dpl200/mnn2::dpl200 CAI-4 chemical compound accumulation: decreased mannan C. albicans orf19.2347 ORF MNN2 CAL0000743 PMID: 23633946|CGD_REF: CAL0000172007 homozygous diploid, classical genetics null mnn2::dpl200/mnn2::dpl200 CAI-4 induction of host response: decreased deletion of MNN2 resulted in a 67% reduction in TNF-alpha secretion from PBMCs C. albicans orf19.2347 ORF MNN2 CAL0000743 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 invasive growth: decreased solid SLAD media C. albicans orf19.2350 ORF CAL0000747 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.2350 ORF CAL0000747 PMID: 14663094|CGD_REF: CAL0080633 homozygous diploid, systematic mutation set (homozygous insertion mutants generated with URA3-ARG4-URA3 (UAU1) cassette) null BWP17 viable C. albicans orf19.2350 ORF CAL0000747 PMID: 12773383|CGD_REF: CAL0087974 heterozygous diploid, classical genetics (haploinsufficient phenotype assay) unspecified CAI-4 filamentous growth: decreased solid Spider medium transposon insertion proximal to, but not within, the ORF C. albicans orf19.2351 ORF NIT3 CAL0000749 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.2352 ORF CAL0000750 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.2356 ORF CRZ2 CAL0000754 PMID: 20041210|CGD_REF: CAL0124764 homozygous diploid, systematic mutation set null SN152 resistance to chemicals: increased fluconazole strongly resistant C. albicans orf19.2356 ORF CRZ2 CAL0000754 PMID: 15964282|CGD_REF: CAL0114274 homozygous diploid, systematic mutation set (split-marker transposon insertion strategy to disrupt both alleles) null BWP17 viable C. albicans orf19.2356 ORF CRZ2 CAL0000754 PMID: 16468987|CGD_REF: CAL0115525 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.2356 ORF CRZ2 CAL0000754 PMID: 17927701|CGD_REF: CAL0118690 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.2356 ORF CRZ2 CAL0000754 PMID: 17927701|CGD_REF: CAL0118690 homozygous diploid, classical genetics null Not recorded acid pH resistance: decreased pH 2 C. albicans orf19.2356 ORF CRZ2 CAL0000754 PMID: 15964282|CGD_REF: CAL0114274 homozygous diploid, systematic mutation set (split-marker transposon insertion strategy to disrupt both alleles) null BWP17 biofilm formation: normal C. albicans orf19.2356 ORF CRZ2 CAL0000754 PMID: 16468987|CGD_REF: CAL0115525 homozygous diploid, classical genetics null Not recorded metal resistance: normal C. albicans orf19.2356 ORF CRZ2 CAL0000754 PMID: 20041210|CGD_REF: CAL0124764 homozygous diploid, systematic mutation set null SN152 metal resistance: increased copper(2+) strongly resistant C. albicans orf19.2356 ORF CRZ2 CAL0000754 PMID: 22359502|CGD_REF: CAL0000144048 homozygous diploid, classical genetics null BWP17 viable insertion mutant, independent BWP17 and SN152 deletion mutants also tested C. albicans orf19.2356 ORF CRZ2 CAL0000754 PMID: 22359502|CGD_REF: CAL0000144048 homozygous diploid, classical genetics null BWP17 adhesion: decreased insertion mutant, independent BWP17 and SN152 deletion mutants also tested C. albicans orf19.2361 ORF SPT10 CAL0000761 PMID: 19555456|CGD_REF: CAL0123821 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.2362 ORF CAL0000762 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.2362 ORF CAL0000762 PMID: 21135205|CGD_REF: CAL0139967 heterozygous diploid, competitive growth (large-scale identification of genes essential for virulence in mouse) repressible CAI-4 virulence: decreased mouse intravenous infection C. albicans orf19.2364 ORF MIS11 CAL0000766 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.2365 ORF POL2 CAL0000768 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.2365 ORF POL2 CAL0000768 PMID: 20494978|CGD_REF: CAL0125636 heterozygous diploid, classical genetics null BWP17 resistance to chemicals: decreased clotrimazole (75 uM) growth in liquid culture confirmation of mutant phenotypes for heterozygous transposon insertion strains showing sensitivity in a large-scale assay C. albicans orf19.2365 ORF POL2 CAL0000768 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient YPD medium C. albicans orf19.2365 ORF POL2 CAL0000768 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient SC medium C. albicans orf19.2365 ORF POL2 CAL0000768 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient YNB medium C. albicans orf19.2365 ORF POL2 CAL0000768 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient SLAD medium C. albicans orf19.2367 ORF CAL0000771 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.2369 ORF CAL0000773 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.2376 ORF CAL0000789 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.2378 ORF CAL0000790 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.2378 ORF CAL0000790 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: abnormal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.2378 ORF CAL0000790 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: decreased rate liquid synthetic complete medium C. albicans orf19.2378 ORF CAL0000790 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.2379 ORF NOT4 CAL0000791 PMID: 14702416|CGD_REF: CAL0081605 homozygous diploid, classical genetics null CAI-4 germ tube formation: decreased liquid serum-containing or M199 media C. albicans orf19.2379 ORF NOT4 CAL0000791 PMID: 14702416|CGD_REF: CAL0081605 homozygous diploid, classical genetics null CAI-4 hyphal growth: abnormal growth in mouse kidney abnormal hyphal morphology C. albicans orf19.2379 ORF NOT4 CAL0000791 PMID: 14702416|CGD_REF: CAL0081605 homozygous diploid, classical genetics null CAI-4 hyphal growth: decreased growth in mouse kidney C. albicans orf19.2379 ORF NOT4 CAL0000791 PMID: 14702416|CGD_REF: CAL0081605 homozygous diploid, classical genetics null CAI-4 hyphal growth: absent serum-containing, Spider, or M199 solid media C. albicans orf19.2379 ORF NOT4 CAL0000791 PMID: 14702416|CGD_REF: CAL0081605 heterozygous diploid, classical genetics null CAI-4 hyphal growth: decreased serum-containing, Spider, or M199 solid media C. albicans orf19.2379 ORF NOT4 CAL0000791 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.2379 ORF NOT4 CAL0000791 PMID: 14702416|CGD_REF: CAL0081605 homozygous diploid, classical genetics null Not recorded viable wild-type growth rate C. albicans orf19.2379 ORF NOT4 CAL0000791 PMID: 14702416|CGD_REF: CAL0081605 heterozygous diploid, classical genetics null Not recorded viable C. albicans orf19.2379 ORF NOT4 CAL0000791 PMID: 14702416|CGD_REF: CAL0081605 homozygous diploid, classical genetics null Not recorded resistance to chemicals: normal sodium dodecyl sulfate C. albicans orf19.2379 ORF NOT4 CAL0000791 PMID: 14702416|CGD_REF: CAL0081605 homozygous diploid, classical genetics null Not recorded osmotic stress resistance: normal C. albicans orf19.2379 ORF NOT4 CAL0000791 PMID: 14702416|CGD_REF: CAL0081605 homozygous diploid, classical genetics null Not recorded resistance to chemicals: normal 3-aminotriazole C. albicans orf19.2379 ORF NOT4 CAL0000791 PMID: 14702416|CGD_REF: CAL0081605 homozygous diploid, classical genetics null Not recorded resistance to chemicals: normal caffeine C. albicans orf19.2379 ORF NOT4 CAL0000791 PMID: 14702416|CGD_REF: CAL0081605 homozygous diploid, classical genetics null CAF2-1 biofilm formation: decreased C. albicans orf19.2379 ORF NOT4 CAL0000791 PMID: 14702416|CGD_REF: CAL0081605 homozygous diploid, classical genetics null Not recorded virulence: absent mouse intravenous infection C. albicans orf19.2379 ORF NOT4 CAL0000791 PMID: 14702416|CGD_REF: CAL0081605 heterozygous diploid, classical genetics null Not recorded virulence: decreased mouse intravenous infection C. albicans orf19.2382 ORF CAL0000808 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.2383 ORF YKU80 CAL0000809 PMID: 17965250|CGD_REF: CAL0118884 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.2384 ORF MTG1 CAL0000811 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.2385 ORF KTI12 CAL0000813 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.2386 ORF CAL0000815 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.2389 ORF CAL0000817 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.239 ORF CAL0003962 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.2391 ORF CAL0000832 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.2392 ORF CAL0000834 PMID: 14663094|CGD_REF: CAL0080633 homozygous diploid, systematic mutation set (homozygous insertion mutants generated with URA3-ARG4-URA3 (UAU1) cassette) null BWP17 viable C. albicans orf19.2393 ORF CAL0000836 PMID: 15964282|CGD_REF: CAL0114274 homozygous diploid, systematic mutation set (split-marker transposon insertion strategy to disrupt both alleles) null BWP17 viable C. albicans orf19.2393 ORF CAL0000836 PMID: 15964282|CGD_REF: CAL0114274 homozygous diploid, systematic mutation set (split-marker transposon insertion strategy to disrupt both alleles) null BWP17 biofilm formation: normal C. albicans orf19.2394 ORF CAL0000838 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.2395 ORF IME2 CAL0000840 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.2395 ORF IME2 CAL0000840 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, competitive growth (haploinsufficient phenotype assay, barcode deletion set) null SC5314 resistance to chemicals: decreased amphotericin B C. albicans orf19.2396 ORF IFR2 CAL0000841 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.2397 ORF CAL0000842 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.2397.3 ORF CAF0006949 PMID: 20141603|CGD_REF: CAL0124951 homozygous diploid, systematic mutation set (homozygous insertion mutants generated with URA3-ARG4-URA3 (UAU1) cassette) null BWP17 colony appearance: abnormal 10% serum or Spider media at 37 deg C colonies are smoother than wild type but mutant is able to form true hyphae under liquid inducing conditions C. albicans orf19.2397.3 ORF CAF0006949 PMID: 20141603|CGD_REF: CAL0124951 homozygous diploid, systematic mutation set (homozygous insertion mutants generated with URA3-ARG4-URA3 (UAU1) cassette) null BWP17 viable C. albicans orf19.2397.3 ORF CAF0006949 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient YPD medium C. albicans orf19.2397.3 ORF CAF0006949 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient SLAD medium C. albicans orf19.2399 ORF CAL0000844 PMID: 15964282|CGD_REF: CAL0114274 homozygous diploid, systematic mutation set (split-marker transposon insertion strategy to disrupt both alleles) null BWP17 viable C. albicans orf19.2399 ORF CAL0000844 PMID: 15964282|CGD_REF: CAL0114274 homozygous diploid, systematic mutation set (split-marker transposon insertion strategy to disrupt both alleles) null BWP17 biofilm formation: normal C. albicans orf19.24 ORF RTA2 CAL0000522 PMID: 19002381|CGD_REF: CAL0121039 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased econazole C. albicans orf19.24 ORF RTA2 CAL0000522 PMID: 18601908|CGD_REF: CAL0119323 homozygous diploid, classical genetics null Not recorded resistance to chemicals: increased brefeldin A C. albicans orf19.24 ORF RTA2 CAL0000522 PMID: 19002381|CGD_REF: CAL0121039 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased ketoconazole mutant does not display Ca2+ induced resistance to ketoconazole, and sensitivity is not affected by calcineurin inhibitors C. albicans orf19.24 ORF RTA2 CAL0000522 PMID: 19002381|CGD_REF: CAL0121039 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased itraconazole C. albicans orf19.24 ORF RTA2 CAL0000522 PMID: 19002381|CGD_REF: CAL0121039 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.24 ORF RTA2 CAL0000522 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.24 ORF RTA2 CAL0000522 PMID: 19002381|CGD_REF: CAL0121039 heterozygous diploid, classical genetics null Not recorded viable C. albicans orf19.24 ORF RTA2 CAL0000522 PMID: 19002381|CGD_REF: CAL0121039 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased voriconazole C. albicans orf19.24 ORF RTA2 CAL0000522 PMID: 19002381|CGD_REF: CAL0121039 homozygous diploid, classical genetics null Not recorded chemical compound excretion: increased dihydrosphingosine defect in export of dihydrosphingosine (DHS) C. albicans orf19.24 ORF RTA2 CAL0000522 PMID: 19002381|CGD_REF: CAL0121039 homozygous diploid, classical genetics null Not recorded resistance to chemicals: increased myriocin myriocin decreases sphingolipid long chain base accumulation in wild type C. albicans orf19.24 ORF RTA2 CAL0000522 PMID: 19002381|CGD_REF: CAL0121039 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased triazoles increased cell membrane damage upon azole treatment C. albicans orf19.24 ORF RTA2 CAL0000522 PMID: 18601908|CGD_REF: CAL0119323 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased triazoles C. albicans orf19.24 ORF RTA2 CAL0000522 PMID: 18601908|CGD_REF: CAL0119323 heterozygous diploid, classical genetics overexpression Not recorded resistance to chemicals: increased triazoles C. albicans orf19.24 ORF RTA2 CAL0000522 PMID: 19002381|CGD_REF: CAL0121039 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased fumonisin B1 fumonisin B1 increases sphingolipid long chain base accumulation in wild type C. albicans orf19.24 ORF RTA2 CAL0000522 PMID: 19002381|CGD_REF: CAL0121039 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased fluconazole Ca2+ induced resistance to fluconazole is abolished, and sensitivity is not affected by calcineurin inhibitors C. albicans orf19.240 ORF PAM17 CAL0003975 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.2401 ORF CAL0001444 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.2402 ORF SSU72 CAL0001446 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.2404 ORF CAL0001450 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.2404 ORF CAL0001450 PMID: 20494978|CGD_REF: CAL0125636 heterozygous diploid, classical genetics null BWP17 resistance to chemicals: decreased clotrimazole (75 uM) growth in liquid culture confirmation of mutant phenotypes for heterozygous transposon insertion strains showing sensitivity in a large-scale assay C. albicans orf19.2404 ORF CAL0001450 PMID: 21135205|CGD_REF: CAL0139967 heterozygous diploid, competitive growth (large-scale identification of genes essential for virulence in mouse) repressible CAI-4 virulence: decreased mouse intravenous infection C. albicans orf19.2407 ORF DPS1-1 CAL0001457 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.2410 ORF SYS3 CAL0001468 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.2411 ORF SYN8 CAL0001470 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.2415 ORF CAL0001478 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.2416.1 ORF MLC1 CAF0006950 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.2417 ORF SMC5 CAL0001481 PMID: 12773383|CGD_REF: CAL0087974 heterozygous diploid, classical genetics (haploinsufficient phenotype assay) null CAI-4 viable heterozygous transposon insertion C. albicans orf19.2417 ORF SMC5 CAL0001481 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.2417 ORF SMC5 CAL0001481 PMID: 12773383|CGD_REF: CAL0087974 heterozygous diploid, classical genetics (haploinsufficient phenotype assay) null CAI-4 filamentous growth: increased solid Spider medium or solid YEPD plus serum heterozygous transposon insertion C. albicans orf19.2417 ORF SMC5 CAL0001481 PMID: 20494978|CGD_REF: CAL0125636 heterozygous diploid, classical genetics null BWP17 resistance to chemicals: decreased clotrimazole (75 uM) growth in liquid culture confirmation of mutant phenotypes for heterozygous transposon insertion strains showing sensitivity in a large-scale assay C. albicans orf19.2417 ORF SMC5 CAL0001481 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 invasive growth: decreased solid SLAD media C. albicans orf19.2418 ORF CAL0001483 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient YPD medium C. albicans orf19.2418 ORF CAL0001483 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient SC medium C. albicans orf19.2418 ORF CAL0001483 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient YNB medium C. albicans orf19.2418 ORF CAL0001483 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient SLAD medium C. albicans orf19.242 ORF SAP8 CAL0003978 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.242 ORF SAP8 CAL0003978 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.242 ORF SAP8 CAL0003978 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.242 ORF SAP8 CAL0003978 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.242 ORF SAP8 CAL0003978 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.242.2 ORF CAF0006892 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.2422 ORF ARC1 CAL0001493 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.2422 ORF ARC1 CAL0001493 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 invasive growth: decreased solid SLAD media C. albicans orf19.2423 ORF ZCF11 CAL0001494 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.2423 ORF ZCF11 CAL0001494 PMID: 19779551|CGD_REF: CAL0124331 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.2423 ORF ZCF11 CAL0001494 PMID: 19779551|CGD_REF: CAL0124331 homozygous diploid, classical genetics null Not recorded colony appearance: abnormal solid Spider medium C. albicans orf19.2423 ORF ZCF11 CAL0001494 PMID: 12773383|CGD_REF: CAL0087974 heterozygous diploid, classical genetics (haploinsufficient phenotype assay) unspecified CAI-4 filamentous growth: abnormal transposon insertion proximal to, but not within, the ORF C. albicans orf19.2425 ORF HGT18 CAL0001498 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.2426 ORF CAL0001500 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.2429 ORF CAL0001504 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.2429 ORF CAL0001504 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.2429 ORF CAL0001504 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.2429 ORF CAL0001504 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.2432 ORF HAC1 CAL0001516 PMID: 18602013|CGD_REF: CAL0119327 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased Calcofluor White C. albicans orf19.2432 ORF HAC1 CAL0001516 PMID: 18602013|CGD_REF: CAL0119327 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.2432 ORF HAC1 CAL0001516 PMID: 15964282|CGD_REF: CAL0114274 homozygous diploid, systematic mutation set (split-marker transposon insertion strategy to disrupt both alleles) null BWP17 inviable homozygous null mutant strain could not be recovered, suggesting that the gene is essential under the selection conditions C. albicans orf19.2432 ORF HAC1 CAL0001516 PMID: 18602013|CGD_REF: CAL0119327 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased 1,4-dithiothreitol C. albicans orf19.2432 ORF HAC1 CAL0001516 PMID: 18602013|CGD_REF: CAL0119327 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased tunicamycin C. albicans orf19.2432 ORF HAC1 CAL0001516 PMID: 18602013|CGD_REF: CAL0119327 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased Congo Red C. albicans orf19.2432 ORF HAC1 CAL0001516 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient YPD medium C. albicans orf19.2434 ORF NPL4 CAL0001521 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.2435 ORF MSI3 CAL0001523 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.2435 ORF MSI3 CAL0001523 PMID: 22713118|CGD_REF: CAL0000157493 heterozygous diploid, classical genetics repressible tet-MSI3/msi3::URA3 CAI-8 virulence: decreased repressive conditions, doxycycline mouse intravenous infection C. albicans orf19.2435 ORF MSI3 CAL0001523 PMID: 22713118|CGD_REF: CAL0000157493 heterozygous diploid, classical genetics repressible tet-MSI3/msi3::URA3 CAI-8 inviable repressive conditions, doxycycline C. albicans orf19.2435 ORF MSI3 CAL0001523 PMID: 22713118|CGD_REF: CAL0000157493 heterozygous diploid, classical genetics repressible tet-MSI3/msi3::URA3 CAI-8 resistance to chemicals: decreased fluconazole repressive conditions, doxycycline C. albicans orf19.2436 ORF CAL0001525 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.2437 ORF ARC35 CAL0001527 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.2437 ORF ARC35 CAL0001527 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, competitive growth (haploinsufficient phenotype assay, barcode deletion set) null SC5314 resistance to chemicals: decreased cytochalasin D C. albicans orf19.2437 ORF ARC35 CAL0001527 PMID: 21135205|CGD_REF: CAL0139967 heterozygous diploid, large-scale survey (large-scale identification of genes essential for virulence in mouse) repressible CAI-4 virulence: absent mouse intravenous infection C. albicans orf19.2438 ORF CAL0001528 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.2440 ORF CAL0001537 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.2443 ORF RGD1 CAL0001542 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.2443 ORF RGD1 CAL0001542 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.2443 ORF RGD1 CAL0001542 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.2443 ORF RGD1 CAL0001542 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.2443 ORF RGD1 CAL0001542 PMID: 20637818|CGD_REF: CAL0125963 homozygous diploid, classical genetics null BWP17 acid pH resistance: decreased pH 2.8 C. albicans orf19.2443 ORF RGD1 CAL0001542 PMID: 20637818|CGD_REF: CAL0125963 homozygous diploid, classical genetics null BWP17 hyphal growth: increased liquid YEPD plus 20% fetal calf serum, 37 degrees C increased hyphal length in liquid medium C. albicans orf19.2443 ORF RGD1 CAL0001542 PMID: 20637818|CGD_REF: CAL0125963 homozygous diploid, classical genetics null BWP17 filamentous growth: increased solid YEPS medium (2% sucrose instead of dextrose as in YEPD) increased peripheral hyphal outgrowths C. albicans orf19.2443 ORF RGD1 CAL0001542 PMID: 20637818|CGD_REF: CAL0125963 homozygous diploid, classical genetics null BWP17 invasive growth: increased embedded agar conditions C. albicans orf19.2443 ORF RGD1 CAL0001542 PMID: 20637818|CGD_REF: CAL0125963 homozygous diploid, classical genetics overexpression BWP17 hyphal growth: decreased liquid YEPD plus 20% fetal calf serum, 37 degrees C C. albicans orf19.2443 ORF RGD1 CAL0001542 PMID: 20637818|CGD_REF: CAL0125963 homozygous diploid, classical genetics null BWP17 viable C. albicans orf19.2443 ORF RGD1 CAL0001542 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.2444 ORF CHS7 CAL0001543 PMID: 16079341|CGD_REF: CAL0114434 homozygous diploid, classical genetics null Not recorded resistance to chemicals: increased Calcofluor White C. albicans orf19.2444 ORF CHS7 CAL0001543 PMID: 16079341|CGD_REF: CAL0114434 homozygous diploid, classical genetics null CAI-4 flocculation: increased C. albicans orf19.2444 ORF CHS7 CAL0001543 PMID: 16079341|CGD_REF: CAL0114434 homozygous diploid, classical genetics null CAI-4 hyphal growth: abnormal solid media curved hyphae with irregular swellings of hyphal wall C. albicans orf19.2444 ORF CHS7 CAL0001543 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.2444 ORF CHS7 CAL0001543 PMID: 16079341|CGD_REF: CAL0114434 heterozygous diploid, classical genetics null Not recorded viable C. albicans orf19.2444 ORF CHS7 CAL0001543 PMID: 16079341|CGD_REF: CAL0114434 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.2444 ORF CHS7 CAL0001543 PMID: 16079341|CGD_REF: CAL0114434 homozygous diploid, classical genetics null Not recorded chitin deposition: abnormal decreased chitin content, septal abnormalities, and prominent bud scars C. albicans orf19.2444 ORF CHS7 CAL0001543 PMID: 16079341|CGD_REF: CAL0114434 heterozygous diploid, classical genetics null Not recorded chitin deposition: decreased slight reduction in chitin content of yeast-form cells C. albicans orf19.2444 ORF CHS7 CAL0001543 PMID: 16079341|CGD_REF: CAL0114434 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased nikkomycin Z C. albicans orf19.2444 ORF CHS7 CAL0001543 PMID: 16079341|CGD_REF: CAL0114434 homozygous diploid, classical genetics null CAI-4 filamentous growth: increased C. albicans orf19.2444 ORF CHS7 CAL0001543 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: increased growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.2444 ORF CHS7 CAL0001543 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.2444 ORF CHS7 CAL0001543 PMID: 16079341|CGD_REF: CAL0114434 homozygous diploid, classical genetics null Not recorded virulence: decreased mouse intravenous infection C. albicans orf19.2444 ORF CHS7 CAL0001543 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.2444 ORF CHS7 CAL0001543 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.2445 ORF CAL0001545 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.2446 ORF CAL0001547 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.2446 ORF CAL0001547 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.2446 ORF CAL0001547 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.2446 ORF CAL0001547 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.2446 ORF CAL0001547 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.2447 ORF CAL0001548 PMID: 22073120|CGD_REF: CAL0000143592 homozygous diploid, classical genetics null BWP17 viable C. albicans orf19.2447 ORF CAL0001548 PMID: 22073120|CGD_REF: CAL0000143592 homozygous diploid, classical genetics null BWP17 invasive growth: decreased decreased agar invasion C. albicans orf19.2451 ORF PGA45 CAL0001553 PMID: 18765290|CGD_REF: CAL0119430 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.2451 ORF PGA45 CAL0001553 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.2451 ORF PGA45 CAL0001553 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.2451 ORF PGA45 CAL0001553 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.2451 ORF PGA45 CAL0001553 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.2454 ORF PHO87 CAL0001557 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.2454 ORF PHO87 CAL0001557 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 invasive growth: decreased solid SLAD media C. albicans orf19.2457 ORF CAL0001562 PMID: 23516516|CGD_REF: CAL0000158761 homozygous diploid, classical genetics null SC5314 viable C. albicans orf19.2457 ORF CAL0001562 PMID: 23516516|CGD_REF: CAL0000158761 homozygous diploid, classical genetics null SC5314 filamentous growth: normal C. albicans orf19.2458 ORF SIP5 CAL0001563 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.2458 ORF SIP5 CAL0001563 PMID: 15964282|CGD_REF: CAL0114274 homozygous diploid, systematic mutation set (split-marker transposon insertion strategy to disrupt both alleles) null BWP17 viable C. albicans orf19.2458 ORF SIP5 CAL0001563 PMID: 15964282|CGD_REF: CAL0114274 homozygous diploid, systematic mutation set (split-marker transposon insertion strategy to disrupt both alleles) null BWP17 biofilm formation: normal C. albicans orf19.2459 ORF CAL0001564 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.2460 ORF CAL0001577 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.2460 ORF CAL0001577 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.2460 ORF CAL0001577 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.2460 ORF CAL0001577 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.2460 ORF CAL0001577 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 invasive growth: decreased solid SLAD media C. albicans orf19.2461 ORF PRN4 CAL0001579 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.2461 ORF PRN4 CAL0001579 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.2461 ORF PRN4 CAL0001579 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.2461 ORF PRN4 CAL0001579 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.2461 ORF PRN4 CAL0001579 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.2462 ORF PRN3 CAL0001581 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.2463 ORF PRN2 CAL0001583 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.2463 ORF PRN2 CAL0001583 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.2463 ORF PRN2 CAL0001583 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.2463 ORF PRN2 CAL0001583 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.2463 ORF PRN2 CAL0001583 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.2467 ORF PRN1 CAL0001587 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.2467 ORF PRN1 CAL0001587 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.2467 ORF PRN1 CAL0001587 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.2467 ORF PRN1 CAL0001587 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.2467 ORF PRN1 CAL0001587 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.2469 ORF RAD10 CAL0001589 PMID: 18667577|CGD_REF: CAL0119361 homozygous diploid, classical genetics null Not recorded UV resistance: decreased C. albicans orf19.2469 ORF RAD10 CAL0001589 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.2469 ORF RAD10 CAL0001589 PMID: 18667577|CGD_REF: CAL0119361 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.2475 ORF PGA26 CAL0001610 PMID: 21439008|CGD_REF: CAL0141853 homozygous diploid, classical genetics null pga26::hisG/pga26::hisG CAI-4 viable C. albicans orf19.2475 ORF PGA26 CAL0001610 PMID: 21439008|CGD_REF: CAL0141853 homozygous diploid, classical genetics null pga26::hisG/pga26::hisG CAI-4 resistance to chemicals: decreased Calcofluor White C. albicans orf19.2475 ORF PGA26 CAL0001610 PMID: 21439008|CGD_REF: CAL0141853 homozygous diploid, classical genetics null pga26::hisG/pga26::hisG CAI-4 resistance to chemicals: decreased Congo Red C. albicans orf19.2475 ORF PGA26 CAL0001610 PMID: 21439008|CGD_REF: CAL0141853 homozygous diploid, classical genetics null pga26::hisG/pga26::hisG CAI-4 filamentous growth: increased C. albicans orf19.2475 ORF PGA26 CAL0001610 PMID: 21439008|CGD_REF: CAL0141853 homozygous diploid, classical genetics null pga26::hisG/pga26::hisG CAI-4 biofilm formation: increased C. albicans orf19.2475 ORF PGA26 CAL0001610 PMID: 21439008|CGD_REF: CAL0141853 homozygous diploid, classical genetics null pga26::hisG/pga26::hisG CAI-4 virulence: decreased mouse intravenous infection C. albicans orf19.2475 ORF PGA26 CAL0001610 PMID: 21439008|CGD_REF: CAL0141853 homozygous diploid, classical genetics null pga26::hisG/pga26::hisG CAI-4 resistance to enzymatic treatment: decreased endo-beta-1,3-glucanase (zymolyase) C. albicans orf19.2476 ORF CAL0001611 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.2476 ORF CAL0001611 PMID: 17873081|CGD_REF: CAL0118685 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.2476 ORF CAL0001611 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient YPD medium C. albicans orf19.2476 ORF CAL0001611 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient SC medium C. albicans orf19.2476 ORF CAL0001611 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient YNB medium C. albicans orf19.248 ORF APL5 CAL0003993 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.248 ORF APL5 CAL0003993 PMID: 14663094|CGD_REF: CAL0080633 homozygous diploid, systematic mutation set (homozygous insertion mutants generated with URA3-ARG4-URA3 (UAU1) cassette) null BWP17 viable C. albicans orf19.248 ORF APL5 CAL0003993 PMID: 23856128|CGD_REF: CAL0000172540 homozygous diploid, classical genetics null BWP17 resistance to chemicals: decreased propolis C. albicans orf19.2480.1 ORF AUT7 CAF0006954 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.2481 ORF CAL0001628 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.2484 ORF CAL0001633 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: decreased growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.2484 ORF CAL0001633 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.2484 ORF CAL0001633 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.2485 ORF CAL0001635 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.2488 ORF FAL1 CAL0001638 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.2488 ORF FAL1 CAL0001638 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient YNB medium C. albicans orf19.2488 ORF FAL1 CAL0001638 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient SLAD medium C. albicans orf19.2489 ORF CAL0001639 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.2492 ORF STE3 CAL0001656 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.2492 ORF STE3 CAL0001656 PMID: 18162580|CGD_REF: CAL0118948 homozygous diploid, classical genetics null Not recorded phenotypic switching: normal C. albicans orf19.2492 ORF STE3 CAL0001656 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.2492 ORF STE3 CAL0001656 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.2492 ORF STE3 CAL0001656 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.2492 ORF STE3 CAL0001656 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.2494 ORF CAL0001659 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.2496 ORF ATO2 CAL0001662 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.25 ORF CAL0000523 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.250 ORF SLC1 CAL0004001 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.250 ORF SLC1 CAL0004001 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 invasive growth: decreased solid SLAD media C. albicans orf19.2500 ORF CAL0002351 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: decreased growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.2500 ORF CAL0002351 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: decreased rate liquid synthetic complete medium C. albicans orf19.2500 ORF CAL0002351 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.2501 ORF FLC1 CAL0002353 PMID: 16717099|CGD_REF: CAL0116315 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.2501 ORF FLC1 CAL0002353 PMID: 16717099|CGD_REF: CAL0116315 heterozygous diploid, classical genetics overexpression Not recorded nutrient uptake: increased heme C. albicans orf19.2501 ORF FLC1 CAL0002353 PMID: 16717099|CGD_REF: CAL0116315 homozygous diploid, classical genetics null Not recorded small molecule transport: decreased heme decreased heme uptake C. albicans orf19.2501 ORF FLC1 CAL0002353 PMID: 16717099|CGD_REF: CAL0116315 homozygous diploid, classical genetics null BWP17 filamentous growth: decreased C. albicans orf19.2501 ORF FLC1 CAL0002353 PMID: 21414038|CGD_REF: CAL0141808 homozygous diploid, classical genetics null BWP17 viable C. albicans orf19.2504 ORF BMS1 CAL0002359 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, competitive growth (haploinsufficient phenotype assay, barcode deletion set) null SC5314 resistance to chemicals: increased flucytosine C. albicans orf19.2504 ORF BMS1 CAL0002359 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.2504 ORF BMS1 CAL0002359 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient YPD medium C. albicans orf19.2504 ORF BMS1 CAL0002359 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient YNB medium C. albicans orf19.2505 ORF CAL0002362 PMID: 20494978|CGD_REF: CAL0125636 heterozygous diploid, classical genetics null BWP17 resistance to chemicals: decreased clotrimazole (75 uM) growth in liquid culture confirmation of mutant phenotypes for heterozygous transposon insertion strains showing sensitivity in a large-scale assay C. albicans orf19.2507 ORF ARP9 CAL0002366 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.2507 ORF ARP9 CAL0002366 PMID: 12524333|CGD_REF: CAL0080691 homozygous diploid, systematic mutation set (homozygous insertion mutants generated with URA3-ARG4-URA3 (UAU1) cassette) null BWP17 inviable homozygous null mutant strain could not be recovered, suggesting that the gene is essential under the selection conditions C. albicans orf19.2508 ORF PRM9 CAL0002367 PMID: 14663094|CGD_REF: CAL0080633 homozygous diploid, systematic mutation set (homozygous insertion mutants generated with URA3-ARG4-URA3 (UAU1) cassette) null BWP17 viable C. albicans orf19.2508 ORF PRM9 CAL0002367 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 invasive growth: decreased solid SLAD media C. albicans orf19.251 ORF GLX3 CAL0004002 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.251 ORF GLX3 CAL0004002 PMID: 24302734|CGD_REF: CAL0000173716 homozygous diploid, classical genetics null SC5314 viable C. albicans orf19.251 ORF GLX3 CAL0004002 PMID: 24302734|CGD_REF: CAL0000173716 homozygous diploid, classical genetics null SC5314 resistance to chemicals: decreased methylglyoxal C. albicans orf19.251 ORF GLX3 CAL0004002 PMID: 24302734|CGD_REF: CAL0000173716 homozygous diploid, classical genetics null SC5314 vegetative growth: decreased rate glycerol as carbon source C. albicans orf19.2514 ORF CAL0002386 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.2514 ORF CAL0002386 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 invasive growth: decreased solid SLAD media C. albicans orf19.2517 ORF CAL0002394 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.2517 ORF CAL0002394 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.2517 ORF CAL0002394 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.2517 ORF CAL0002394 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.2517 ORF CAL0002394 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.2518 ORF CAL0002396 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.2519 ORF CAL0002398 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.252 ORF CAL0004004 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.2521 ORF CAL0002408 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 invasive growth: decreased solid SLAD media C. albicans orf19.2524 ORF MGE1 CAL0002414 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.2525 ORF LYS12 CAL0002415 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.2527 ORF CAL0002419 PMID: 21414038|CGD_REF: CAL0141808 homozygous diploid, classical genetics null BWP17 viable C. albicans orf19.2528 ORF CAL0002421 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.2528 ORF CAL0002421 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 invasive growth: decreased solid SLAD media C. albicans orf19.2528 ORF CAL0002421 PMID: 21135205|CGD_REF: CAL0139967 heterozygous diploid, large-scale survey (large-scale identification of genes essential for virulence in mouse) repressible CAI-4 virulence: absent mouse intravenous infection C. albicans orf19.2531 ORF CSP37 CAL0002434 PMID: 9244249|CGD_REF: CAL0081088 homozygous diploid, classical genetics null Not recorded germ tube formation: normal GlcNAc-containing or Lee's media C. albicans orf19.2531 ORF CSP37 CAL0002434 PMID: 9244249|CGD_REF: CAL0081088 homozygous diploid, classical genetics null Not recorded viable wild-type growth rate C. albicans orf19.2531 ORF CSP37 CAL0002434 PMID: 9244249|CGD_REF: CAL0081088 homozygous diploid, classical genetics null Not recorded adhesion: decreased adhesion to polystyrene C. albicans orf19.2531 ORF CSP37 CAL0002434 PMID: 9244249|CGD_REF: CAL0081088 homozygous diploid, classical genetics null Not recorded virulence: decreased mouse intravenous infection C. albicans orf19.2532 ORF PRS CAL0002436 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.2533.1 ORF CAF0006956 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient YPD medium C. albicans orf19.2533.1 ORF CAF0006956 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient YPD medium C. albicans orf19.2533.1 ORF CAF0006956 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient YPD medium C. albicans orf19.2533.1 ORF CAF0006956 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient YPD medium C. albicans orf19.2533.1 ORF CAF0006956 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient YNB medium C. albicans orf19.2533.1 ORF CAF0006956 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient SLAD medium C. albicans orf19.2534 ORF PIN4 CAL0002441 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.2534 ORF PIN4 CAL0002441 PMID: 12773383|CGD_REF: CAL0087974 heterozygous diploid, classical genetics (haploinsufficient phenotype assay) unspecified CAI-4 filamentous growth: increased solid YEPD plus serum transposon insertion proximal to, but not within, the ORF C. albicans orf19.2534 ORF PIN4 CAL0002441 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.2534 ORF PIN4 CAL0002441 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.2534 ORF PIN4 CAL0002441 PMID: 12773383|CGD_REF: CAL0087974 heterozygous diploid, classical genetics (haploinsufficient phenotype assay) null CAI-4 filamentous growth: decreased solid Spider medium heterozygous transposon insertion C. albicans orf19.2534 ORF PIN4 CAL0002441 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.2534 ORF PIN4 CAL0002441 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.2538 ORF PTC2 CAL0002447 PMID: 18708562|CGD_REF: CAL0119375 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.2538 ORF PTC2 CAL0002447 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.2538 ORF PTC2 CAL0002447 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: abnormal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.2538 ORF PTC2 CAL0002447 PMID: 18708562|CGD_REF: CAL0119375 homozygous diploid, classical genetics null Not recorded virulence: decreased insect infection C. albicans orf19.2538 ORF PTC2 CAL0002447 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.2538 ORF PTC2 CAL0002447 PMID: 20641018|CGD_REF: CAL0126129 homozygous diploid, classical genetics null RM1000 viable C. albicans orf19.2538 ORF PTC2 CAL0002447 PMID: 20641018|CGD_REF: CAL0126129 heterozygous diploid, classical genetics null RM1000 viable C. albicans orf19.2538 ORF PTC2 CAL0002447 PMID: 20641018|CGD_REF: CAL0126129 homozygous diploid, classical genetics null RM1000 resistance to chemicals: decreased sodium dodecyl sulfate (0.02%) C. albicans orf19.2538 ORF PTC2 CAL0002447 PMID: 20641018|CGD_REF: CAL0126129 homozygous diploid, classical genetics null RM1000 resistance to chemicals: decreased fluconazole (4 ug/ml) C. albicans orf19.2538 ORF PTC2 CAL0002447 PMID: 20641018|CGD_REF: CAL0126129 homozygous diploid, classical genetics null RM1000 resistance to chemicals: decreased ketoconazole (0.1 ug/ml) C. albicans orf19.2538 ORF PTC2 CAL0002447 PMID: 20641018|CGD_REF: CAL0126129 homozygous diploid, classical genetics null RM1000 resistance to chemicals: decreased methyl methanesulfonate (0.01%) C. albicans orf19.2538 ORF PTC2 CAL0002447 PMID: 20641018|CGD_REF: CAL0126129 homozygous diploid, classical genetics null RM1000 resistance to chemicals: decreased hydroxyurea (40 mM) C. albicans orf19.2538 ORF PTC2 CAL0002447 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.2541 ORF CAL0002458 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.2544 ORF CAL0002463 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.2545 ORF DOT6 CAL0002464 PMID: 22581526|CGD_REF: CAL0000157314 homozygous diploid, systematic mutation set null BWP17 resistance to chemicals: decreased flucytosine C. albicans orf19.2546 ORF TRP2 CAL0002466 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.2546 ORF TRP2 CAL0002466 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient SLAD medium C. albicans orf19.2549 ORF SHP1 CAL0002468 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.2549 ORF SHP1 CAL0002468 PMID: 22542681|CGD_REF: CAL0000157242 homozygous diploid, classical genetics null shp1::ARG4/shp1::HIS1 BWP17 cell cycle progression through the G2/M phase transition: delayed C. albicans orf19.2549 ORF SHP1 CAL0002468 PMID: 22542681|CGD_REF: CAL0000157242 homozygous diploid, classical genetics null shp1::ARG4/shp1::HIS1 BWP17 hyphal growth: decreased rate C. albicans orf19.2549 ORF SHP1 CAL0002468 PMID: 22542681|CGD_REF: CAL0000157242 homozygous diploid, classical genetics null shp1::ARG4/shp1::HIS1 BWP17 heat sensitivity: decreased 42 deg C. albicans orf19.2549 ORF SHP1 CAL0002468 PMID: 22542681|CGD_REF: CAL0000157242 homozygous diploid, classical genetics null shp1::ARG4/shp1::HIS1 BWP17 resistance to chemicals: decreased methyl methanesulfonate C. albicans orf19.2549 ORF SHP1 CAL0002468 PMID: 22542681|CGD_REF: CAL0000157242 homozygous diploid, classical genetics null shp1::ARG4/shp1::HIS1 BWP17 resistance to chemicals: decreased hydroxyurea C. albicans orf19.2549 ORF SHP1 CAL0002468 PMID: 22542681|CGD_REF: CAL0000157242 homozygous diploid, classical genetics null shp1::ARG4/shp1::HIS1 BWP17 resistance to chemicals: decreased 4-nitroquinoline N-oxide C. albicans orf19.2549 ORF SHP1 CAL0002468 PMID: 22542681|CGD_REF: CAL0000157242 homozygous diploid, classical genetics null shp1::ARG4/shp1::HIS1 BWP17 vegetative growth: decreased rate C. albicans orf19.2549 ORF SHP1 CAL0002468 PMID: 22542681|CGD_REF: CAL0000157242 homozygous diploid, classical genetics null shp1::ARG4/shp1::HIS1 BWP17 viable C. albicans orf19.2549 ORF SHP1 CAL0002468 PMID: 22542681|CGD_REF: CAL0000157242 homozygous diploid, classical genetics null shp1::ARG4/shp1::HIS1 BWP17 cell shape: abnormal elongated cells C. albicans orf19.2549 ORF SHP1 CAL0002468 PMID: 22542681|CGD_REF: CAL0000157242 homozygous diploid, classical genetics null shp1::ARG4/shp1::HIS1 BWP17 UV resistance: decreased C. albicans orf19.255 ORF ZCF1 CAL0004010 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.255 ORF ZCF1 CAL0004010 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.255 ORF ZCF1 CAL0004010 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.255 ORF ZCF1 CAL0004010 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.2551 ORF MET6 CAL0002475 PMID: 17935688|CGD_REF: CAL0118712 heterozygous diploid, classical genetics null Not recorded viable C. albicans orf19.2551 ORF MET6 CAL0002475 PMID: 17935688|CGD_REF: CAL0118712 homozygous diploid, classical genetics null Not recorded inviable homozygous null mutant strain could not be recovered, suggesting that the gene is essential under the selection conditions C. albicans orf19.2551 ORF MET6 CAL0002475 PMID: 17935688|CGD_REF: CAL0118712 heterozygous diploid, classical genetics repressible Not recorded auxotrophy methionine expressed at a low level from the GAL1 promoter under glucose repression C. albicans orf19.2552 ORF CAL0002477 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.2553 ORF CAL0002479 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.2555 ORF URA5 CAL0002481 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.2555 ORF URA5 CAL0002481 PMID: 21135205|CGD_REF: CAL0139967 heterozygous diploid, large-scale survey (large-scale identification of genes essential for virulence in mouse) repressible CAI-4 virulence: absent mouse intravenous infection C. albicans orf19.2557 ORF SEC65 CAL0002482 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.2559 ORF CDC4 CAL0002484 PMID: 15814839|CGD_REF: CAL0114183 homozygous diploid, classical genetics null CAI-4 germ tube formation: increased serum-containing medium germ tube formation is also accelerated C. albicans orf19.2559 ORF CDC4 CAL0002484 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.2559 ORF CDC4 CAL0002484 PMID: 15814839|CGD_REF: CAL0114183 heterozygous diploid, classical genetics null Not recorded viable C. albicans orf19.2559 ORF CDC4 CAL0002484 PMID: 15814839|CGD_REF: CAL0114183 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.2559 ORF CDC4 CAL0002484 PMID: 16228290|CGD_REF: CAL0115361 heterozygous diploid, classical genetics repressible Not recorded viable C. albicans orf19.2559 ORF CDC4 CAL0002484 PMID: 15814839|CGD_REF: CAL0114183 heterozygous diploid, classical genetics repressible CAI-4 filamentous growth: increased hyperfilamentous, similar to homozygous null mutant C. albicans orf19.2559 ORF CDC4 CAL0002484 PMID: 15814839|CGD_REF: CAL0114183 homozygous diploid, classical genetics null CAI-4 filamentous growth: increased hyperfilamentous; on solid media grow as hyphae with some pseudohyphae, form aerial hyphal bundles and invade agar; in liquid media grow as pseudohyphae with some hyphae and form mycelial balls C. albicans orf19.2559 ORF CDC4 CAL0002484 PMID: 16228290|CGD_REF: CAL0115361 heterozygous diploid, classical genetics repressible BWP17 filamentous growth: abnormal C. albicans orf19.2560 ORF CDC60 CAL0002497 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.2560 ORF CDC60 CAL0002497 PMID: 12524333|CGD_REF: CAL0080691 homozygous diploid, systematic mutation set (homozygous insertion mutants generated with URA3-ARG4-URA3 (UAU1) cassette) null BWP17 inviable homozygous null mutant strain could not be recovered, suggesting that the gene is essential under the selection conditions C. albicans orf19.2560 ORF CDC60 CAL0002497 PMID: 21135205|CGD_REF: CAL0139967 heterozygous diploid, large-scale survey (large-scale identification of genes essential for virulence in mouse) repressible CAI-4 virulence: absent mouse intravenous infection C. albicans orf19.2563 ORF CAL0002502 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.2570 ORF MCI4 CAL0002517 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: decreased growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.2570 ORF MCI4 CAL0002517 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: decreased rate liquid synthetic complete medium C. albicans orf19.2570 ORF MCI4 CAL0002517 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.2571 ORF SEC4 CAL0002519 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.2571 ORF SEC4 CAL0002519 PMID: 14507372|CGD_REF: CAL0088818 heterozygous diploid, large-scale survey (large-scale identification of essential genes by gene replacement and conditional expression (GRACE) method) repressible CAI-4 inviable one allele is deleted and the other is placed under repressible Tet promoter C. albicans orf19.2571 ORF SEC4 CAL0002519 PMID: 10572126|CGD_REF: CAL0081325 homozygous diploid, classical genetics null sec4::hisG-URA3-hisG CAI-4 inviable homozygous null mutant strain could not be recovered, suggesting that the gene is essential under the selection conditions C. albicans orf19.2571 ORF SEC4 CAL0002519 PMID: 10572126|CGD_REF: CAL0081325 heterozygous diploid, classical genetics dominant negative sec4-S28N CAI-4 protein secretion: decreased C. albicans orf19.2571 ORF SEC4 CAL0002519 PMID: 16178371|CGD_REF: CAL0114737 heterozygous diploid, classical genetics dominant negative sec4-S28N Not recorded protein transport: abnormal mislocalization of Cdr1p and Ftr1p, but not Mlt1p, Cdc10p, Int1p C. albicans orf19.2571 ORF SEC4 CAL0002519 PMID: 10572126|CGD_REF: CAL0081325 heterozygous diploid, classical genetics dominant negative sec4-S28N CAI-4 vegetative growth: decreased rate C. albicans orf19.2571 ORF SEC4 CAL0002519 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, competitive growth (haploinsufficient phenotype assay, barcode deletion set) null SC5314 resistance to chemicals: decreased ergosterol analogs (ECC69 and/or ECC1384) C. albicans orf19.2573 ORF FRS1 CAL0002521 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, competitive growth (haploinsufficient phenotype assay, barcode deletion set) null SC5314 resistance to chemicals: decreased tubercidin C. albicans orf19.2573 ORF FRS1 CAL0002521 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.2574 ORF CAL0002523 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.2575 ORF CAL0002524 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.2580 ORF HST2 CAL0002536 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.2580 ORF HST2 CAL0002536 PMID: 19555456|CGD_REF: CAL0123821 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.2580 ORF HST2 CAL0002536 PMID: 19555456|CGD_REF: CAL0123821 homozygous diploid, classical genetics null Not recorded phenotypic switching: decreased MTLa/MTLa background white-to-opaque switching C. albicans orf19.2581 ORF CAL0002537 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.2582 ORF CAL0002539 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.2583 ORF PTR2 CAL0002541 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.2583 ORF PTR2 CAL0002541 PMID: 23376942|CGD_REF: CAL0000158493 homozygous diploid, classical genetics null SC5314 viable C. albicans orf19.2593 ORF BIO2 CAL0002565 PMID: 21135205|CGD_REF: CAL0139967 heterozygous diploid, large-scale survey (large-scale identification of genes essential for virulence in mouse) repressible CAI-4 virulence: absent mouse intravenous infection C. albicans orf19.2594 ORF CAL0002566 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.2597 ORF MRS2 CAL0002570 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.2598 ORF VMA4 CAL0002571 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.2599 ORF CRC1 CAL0002572 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.26 ORF CAL0000524 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.260 ORF SLD1 CAL0004027 PMID: 19047747|CGD_REF: CAL0121296 homozygous diploid, classical genetics null Other C. albicans hyphal growth: decreased solid media C. albicans orf19.260 ORF SLD1 CAL0004027 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.260 ORF SLD1 CAL0004027 PMID: 19047747|CGD_REF: CAL0121296 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.260 ORF SLD1 CAL0004027 PMID: 19047747|CGD_REF: CAL0121296 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased sodium dodecyl sulfate C. albicans orf19.260 ORF SLD1 CAL0004027 PMID: 19047747|CGD_REF: CAL0121296 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased fluconazole C. albicans orf19.260 ORF SLD1 CAL0004027 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.260 ORF SLD1 CAL0004027 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.260 ORF SLD1 CAL0004027 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, classical genetics null SN152 virulence: decreased BALB/c mice mouse intravenous infection C. albicans orf19.260 ORF SLD1 CAL0004027 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, classical genetics null SN152 chemical compound accumulation: absent glucosylceramide mature glucosylceramide is absent from cellular membranes C. albicans orf19.260 ORF SLD1 CAL0004027 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.260 ORF SLD1 CAL0004027 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.2600 ORF SPC98 CAL0003350 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.2601 ORF HEM1 CAL0003351 PMID: 15893902|CGD_REF: CAL0114689 homozygous diploid, classical genetics null Not recorded auxotrophy hemin growth is rescued by delta-aminolevulinic acid or by hemin, but not by exogenous ergosterol (indicating lack of ergosterol uptake) C. albicans orf19.2601 ORF HEM1 CAL0003351 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.2601 ORF HEM1 CAL0003351 PMID: 15893902|CGD_REF: CAL0114689 heterozygous diploid, classical genetics null Not recorded viable C. albicans orf19.2601 ORF HEM1 CAL0003351 PMID: 15893902|CGD_REF: CAL0114689 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.2602 ORF OPT1 CAL0003352 PMID: 15474295|CGD_REF: CAL0082145 homozygous diploid, classical genetics null Not recorded toxin resistance: increased toxic ethionine-containing peptide completely resistant C. albicans orf19.2602 ORF OPT1 CAL0003352 PMID: 15474295|CGD_REF: CAL0082145 heterozygous diploid, classical genetics null Not recorded toxin resistance: increased toxic ethionine-containing peptide phenotype is intermediate between that of wild type and the homozygous null mutant C. albicans orf19.2602 ORF OPT1 CAL0003352 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.2602 ORF OPT1 CAL0003352 PMID: 15474295|CGD_REF: CAL0082145 heterozygous diploid, classical genetics null Not recorded viable C. albicans orf19.2602 ORF OPT1 CAL0003352 PMID: 15474295|CGD_REF: CAL0082145 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.2602 ORF OPT1 CAL0003352 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, competitive growth (haploinsufficient phenotype assay, barcode deletion set) null SC5314 resistance to chemicals: decreased amphotericin B C. albicans orf19.2602 ORF OPT1 CAL0003352 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, competitive growth (haploinsufficient phenotype assay, barcode deletion set) null SC5314 resistance to chemicals: decreased ergosterol analogs (ECC69 and/or ECC1384) C. albicans orf19.2604 ORF CAL0003354 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.2604 ORF CAL0003354 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 invasive growth: decreased solid SLAD media C. albicans orf19.2605 ORF PRK1 CAL0003356 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.2605 ORF PRK1 CAL0003356 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.2605 ORF PRK1 CAL0003356 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.2605 ORF PRK1 CAL0003356 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.2605 ORF PRK1 CAL0003356 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.2606 ORF HDA1 CAL0003359 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.2606 ORF HDA1 CAL0003359 PMID: 11404352|CGD_REF: CAL0081365 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.2606 ORF HDA1 CAL0003359 PMID: 11443097|CGD_REF: CAL0081194 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.2606 ORF HDA1 CAL0003359 PMID: 12798685|CGD_REF: CAL0081196 homozygous diploid, classical genetics null CAI-4 viable C. albicans orf19.2606 ORF HDA1 CAL0003359 PMID: 19555456|CGD_REF: CAL0123821 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.2606 ORF HDA1 CAL0003359 PMID: 11404352|CGD_REF: CAL0081365 homozygous diploid, classical genetics null Not recorded phenotypic switching: normal opaque-to-white switching C. albicans orf19.2606 ORF HDA1 CAL0003359 PMID: 11404352|CGD_REF: CAL0081365 homozygous diploid, classical genetics null Not recorded phenotypic switching: increased white-to-opaque switching C. albicans orf19.2606 ORF HDA1 CAL0003359 PMID: 19555456|CGD_REF: CAL0123821 homozygous diploid, classical genetics null Not recorded phenotypic switching: increased MTLa/MTLa background white-to-opaque switching C. albicans orf19.2606 ORF HDA1 CAL0003359 PMID: 20730094|CGD_REF: CAL0126184 homozygous diploid, classical genetics null hda1/hda1 (Tn7::UAU1 disruption) BWP17 viable solid M199 pH8, Spider, embedded agar, SLAD and serum media; liquid Spider, GlcNac and serum media C. albicans orf19.2606 ORF HDA1 CAL0003359 PMID: 20730094|CGD_REF: CAL0126184 homozygous diploid, classical genetics null hda1/hda1 (Tn7::UAU1 disruption) BWP17 filamentous growth: decreased solid M199 pH8, Spider, embedded agar, SLAD and serum media; liquid Spider, GlcNac and serum media C. albicans orf19.2606 ORF HDA1 CAL0003359 PMID: 20730094|CGD_REF: CAL0126184 homozygous diploid, classical genetics null hda1/hda1 (Tn7::UAU1 disruption) BWP17 invasive growth: decreased embedded conditions C. albicans orf19.2606 ORF HDA1 CAL0003359 PMID: 20730094|CGD_REF: CAL0126184 homozygous diploid, classical genetics null hda1/hda1 (Tn7::UAU1 disruption) BWP17 viable C. albicans orf19.2606 ORF HDA1 CAL0003359 PMID: 20730094|CGD_REF: CAL0126184 homozygous diploid, classical genetics null hda1/hda1 (Tn7::UAU1 disruption) BWP17 germ tube formation: delayed C. albicans orf19.2608 ORF ADH5 CAL0003363 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.2608 ORF ADH5 CAL0003363 PMID: 19529758|CGD_REF: CAL0123764 heterozygous diploid, classical genetics overexpression BWP17 biofilm formation: abnormal C. albicans orf19.2608 ORF ADH5 CAL0003363 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 invasive growth: decreased solid SLAD media C. albicans orf19.2609 ORF CET1 CAL0003365 PMID: 12477801|CGD_REF: CAL0080831 homozygous diploid, classical genetics null Not recorded vegetative growth: decreased rate growth defect is more severe at 37 deg C than at 30 deg C C. albicans orf19.2609 ORF CET1 CAL0003365 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.2609 ORF CET1 CAL0003365 PMID: 11737862|CGD_REF: CAL0080988 heterozygous diploid, classical genetics null Not recorded viable C. albicans orf19.2609 ORF CET1 CAL0003365 PMID: 12477801|CGD_REF: CAL0080831 heterozygous diploid, classical genetics null Not recorded viable C. albicans orf19.2609 ORF CET1 CAL0003365 PMID: 12477801|CGD_REF: CAL0080831 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.2609 ORF CET1 CAL0003365 PMID: 14507372|CGD_REF: CAL0088818 heterozygous diploid, large-scale survey (large-scale identification of essential genes by gene replacement and conditional expression (GRACE) method) repressible CAI-4 inviable one allele is deleted and the other is placed under repressible Tet promoter C. albicans orf19.2609 ORF CET1 CAL0003365 PMID: 11737862|CGD_REF: CAL0080988 homozygous diploid, classical genetics null Not recorded inviable homozygous null mutant strain could not be recovered, suggesting that the gene is essential under the selection conditions C. albicans orf19.2609 ORF CET1 CAL0003365 PMID: 12477801|CGD_REF: CAL0080831 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased cycloheximide C. albicans orf19.2609 ORF CET1 CAL0003365 PMID: 10756187|CGD_REF: CAL0080986 unknown ploidy, classical genetics unspecified Other C. albicans viable point mutations identify catalytic site residues required for ATPase activity; truncation mutations define NTPase domain C. albicans orf19.261 ORF CAL0004029 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.2611 ORF MCM6 CAL0003376 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.2612 ORF CAL0003377 PMID: 17555439|CGD_REF: CAL0117968 homozygous diploid, classical genetics null Not recorded survival rate in stationary phase: decreased C. albicans orf19.2612 ORF CAL0003377 PMID: 15964282|CGD_REF: CAL0114274 homozygous diploid, systematic mutation set (split-marker transposon insertion strategy to disrupt both alleles) null BWP17 viable C. albicans orf19.2612 ORF CAL0003377 PMID: 15964282|CGD_REF: CAL0114274 homozygous diploid, systematic mutation set (split-marker transposon insertion strategy to disrupt both alleles) null BWP17 biofilm formation: normal C. albicans orf19.2612 ORF CAL0003377 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.2612 ORF CAL0003377 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.2612 ORF CAL0003377 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.2612 ORF CAL0003377 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.2613 ORF ECM4 CAL0003379 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.2613 ORF ECM4 CAL0003379 PMID: 17873081|CGD_REF: CAL0118685 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.2613 ORF ECM4 CAL0003379 PMID: 12773383|CGD_REF: CAL0087974 heterozygous diploid, classical genetics (haploinsufficient phenotype assay) unspecified CAI-4 filamentous growth: decreased solid Spider medium transposon insertion proximal to, but not within, the ORF C. albicans orf19.2613 ORF ECM4 CAL0003379 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.2613 ORF ECM4 CAL0003379 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.2613 ORF ECM4 CAL0003379 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.2613 ORF ECM4 CAL0003379 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.2614 ORF RSR1 CAL0003380 PMID: 16002653|CGD_REF: CAL0114400 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased Calcofluor White C. albicans orf19.2614 ORF RSR1 CAL0003380 PMID: 9308185|CGD_REF: CAL0080800 homozygous diploid, classical genetics null CAI-4 germ tube formation: decreased liquid Lee's medium C. albicans orf19.2614 ORF RSR1 CAL0003380 PMID: 16002653|CGD_REF: CAL0114400 heterozygous diploid, classical genetics null Not recorded heat sensitivity: normal reintegrant C. albicans orf19.2614 ORF RSR1 CAL0003380 PMID: 16002653|CGD_REF: CAL0114400 homozygous diploid, classical genetics null Not recorded heat sensitivity: increased C. albicans orf19.2614 ORF RSR1 CAL0003380 PMID: 18281602|CGD_REF: CAL0118849 homozygous diploid, classical genetics null BWP17 hyphal growth: abnormal decreased hyphal reorientation in response to ridges on substrate or electric field, decreased hyphal penetration into epithelial cells C. albicans orf19.2614 ORF RSR1 CAL0003380 PMID: 9308185|CGD_REF: CAL0080800 homozygous diploid, classical genetics null CAI-4 hyphal growth: abnormal hyphal growth under noninducing conditions C. albicans orf19.2614 ORF RSR1 CAL0003380 PMID: 16002653|CGD_REF: CAL0114400 heterozygous diploid, classical genetics null BWP17 hyphal growth: normal reintegrant C. albicans orf19.2614 ORF RSR1 CAL0003380 PMID: 12582118|CGD_REF: CAL0080793 heterozygous diploid, classical genetics repressible BWP17 hyphal growth: decreased solid YEPD plus serum C. albicans orf19.2614 ORF RSR1 CAL0003380 PMID: 9308185|CGD_REF: CAL0080800 homozygous diploid, classical genetics null CAI-4 hyphal growth: decreased liquid Lee's medium C. albicans orf19.2614 ORF RSR1 CAL0003380 PMID: 9308185|CGD_REF: CAL0080800 homozygous diploid, classical genetics null CAI-4 hyphal growth: delayed serum-containing medium C. albicans orf19.2614 ORF RSR1 CAL0003380 PMID: 9308185|CGD_REF: CAL0080800 homozygous diploid, classical genetics null Not recorded vegetative growth: decreased liquid SC or YPD media decreased cell density C. albicans orf19.2614 ORF RSR1 CAL0003380 PMID: 12582118|CGD_REF: CAL0080793 heterozygous diploid, classical genetics repressible BWP17 viable wild-type growth rate C. albicans orf19.2614 ORF RSR1 CAL0003380 PMID: 16002653|CGD_REF: CAL0114400 heterozygous diploid, classical genetics null Not recorded viable C. albicans orf19.2614 ORF RSR1 CAL0003380 PMID: 16002653|CGD_REF: CAL0114400 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.2614 ORF RSR1 CAL0003380 PMID: 9308185|CGD_REF: CAL0080800 heterozygous diploid, classical genetics null Not recorded viable C. albicans orf19.2614 ORF RSR1 CAL0003380 PMID: 9308185|CGD_REF: CAL0080800 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.2614 ORF RSR1 CAL0003380 PMID: 16002653|CGD_REF: CAL0114400 homozygous diploid, classical genetics null Not recorded actin cytoskeleton morphology: abnormal yeast-form cells exhibit an increased number of actin patches and some have aberrant morphology; hyphae exhibit delocalized actin patches and randomly oriented actin cables C. albicans orf19.2614 ORF RSR1 CAL0003380 PMID: 9308185|CGD_REF: CAL0080800 homozygous diploid, classical genetics null Not recorded budding pattern: abnormal bud site selection is more random than in wild type C. albicans orf19.2614 ORF RSR1 CAL0003380 PMID: 18281602|CGD_REF: CAL0118849 homozygous diploid, classical genetics null Not recorded interaction with host/environment: abnormal decrease in thigmotropic hyphal reorientation in response to ridges on substrate and in galvanotropic response to electric field C. albicans orf19.2614 ORF RSR1 CAL0003380 PMID: 18281602|CGD_REF: CAL0118849 homozygous diploid, classical genetics null Not recorded interaction with host/environment: abnormal galvanotropic germ tube emergence orientation response and hyphal growth reorientation response do not occur C. albicans orf19.2614 ORF RSR1 CAL0003380 PMID: 16002653|CGD_REF: CAL0114400 homozygous diploid, classical genetics null BWP17 invasive growth: absent growth into agar C. albicans orf19.2614 ORF RSR1 CAL0003380 PMID: 16002653|CGD_REF: CAL0114400 homozygous diploid, classical genetics null Not recorded invasive growth: absent C. albicans orf19.2614 ORF RSR1 CAL0003380 PMID: 16002653|CGD_REF: CAL0114400 homozygous diploid, classical genetics null Not recorded cell size: increased cells are round and enlarged C. albicans orf19.2614 ORF RSR1 CAL0003380 PMID: 9308185|CGD_REF: CAL0080800 homozygous diploid, classical genetics null Not recorded cell size: increased cells are round and enlarged C. albicans orf19.2614 ORF RSR1 CAL0003380 PMID: 12773383|CGD_REF: CAL0087974 heterozygous diploid, classical genetics (haploinsufficient phenotype assay) unspecified CAI-4 filamentous growth: decreased solid Spider medium transposon insertion proximal to, but not within, the ORF C. albicans orf19.2614 ORF RSR1 CAL0003380 PMID: 16002653|CGD_REF: CAL0114400 homozygous diploid, classical genetics null BWP17 filamentous growth: increased increased branching frequency C. albicans orf19.2614 ORF RSR1 CAL0003380 PMID: 16002653|CGD_REF: CAL0114400 homozygous diploid, classical genetics null BWP17 filamentous growth: abnormal solid milk-Tween medium; embedded in agar; solid or liquid serum-containing medium pseudohyphal growth occurs under conditions that support wild-type hyphal growth; hyphae branch from random positions, whereas wild-type branching initiates near a septum C. albicans orf19.2614 ORF RSR1 CAL0003380 PMID: 21407800|CGD_REF: CAL0141800 homozygous diploid, classical genetics null BWP17 interaction with host/environment: abnormal significantly reduced adhesion and damage to epithelial cells, but normal invasion ex vivo model of infection C. albicans orf19.2614 ORF RSR1 CAL0003380 PMID: 18281602|CGD_REF: CAL0118849 homozygous diploid, classical genetics null Not recorded virulence: decreased cultured oral epithelial cells decreased hyphal penetration and capacity to damage cells in vitro model of infection C. albicans orf19.2614 ORF RSR1 CAL0003380 PMID: 18281602|CGD_REF: CAL0118849 homozygous diploid, classical genetics null Not recorded virulence: decreased exhibits decreased tissue invasion in kidney but wild-type fungal burden in kidney and liver mouse intravenous infection C. albicans orf19.2614 ORF RSR1 CAL0003380 PMID: 9308185|CGD_REF: CAL0080800 heterozygous diploid, classical genetics null Not recorded virulence: decreased virulence is intermediate between that of the homozygous null mutant and wild type mouse intravenous infection C. albicans orf19.2614 ORF RSR1 CAL0003380 PMID: 12582118|CGD_REF: CAL0080793 heterozygous diploid, classical genetics misexpression BWP17 virulence: decreased mouse intravenous infection C. albicans orf19.2614 ORF RSR1 CAL0003380 PMID: 9308185|CGD_REF: CAL0080800 homozygous diploid, classical genetics null Not recorded virulence: decreased mouse intravenous infection C. albicans orf19.2615 ORF MDL1 CAL0003383 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.2618 ORF MET2 CAL0003388 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.2618 ORF MET2 CAL0003388 PMID: 21135205|CGD_REF: CAL0139967 heterozygous diploid, competitive growth (large-scale identification of genes essential for virulence in mouse) repressible CAI-4 virulence: normal mouse intravenous infection C. albicans orf19.262 ORF SMC3 CAL0004031 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.262 ORF SMC3 CAL0004031 PMID: 12524333|CGD_REF: CAL0080691 homozygous diploid, systematic mutation set (homozygous insertion mutants generated with URA3-ARG4-URA3 (UAU1) cassette) null BWP17 inviable homozygous null mutant strain could not be recovered, suggesting that the gene is essential under the selection conditions C. albicans orf19.2622 ORF YPT31 CAL0003404 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.2622 ORF YPT31 CAL0003404 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, competitive growth (haploinsufficient phenotype assay, barcode deletion set) null SC5314 resistance to chemicals: decreased ergosterol analogs (ECC69 and/or ECC1384) C. albicans orf19.2623 ORF ECM22 CAL0003406 PMID: 17873081|CGD_REF: CAL0118685 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.2623 ORF ECM22 CAL0003406 PMID: 15964282|CGD_REF: CAL0114274 homozygous diploid, systematic mutation set (split-marker transposon insertion strategy to disrupt both alleles) null BWP17 inviable homozygous null mutant strain could not be recovered, suggesting that the gene is essential under the selection conditions C. albicans orf19.2623 ORF ECM22 CAL0003406 PMID: 22073120|CGD_REF: CAL0000143592 homozygous diploid, classical genetics null BWP17 viable C. albicans orf19.2623 ORF ECM22 CAL0003406 PMID: 22073120|CGD_REF: CAL0000143592 homozygous diploid, classical genetics null BWP17 invasive growth: increased increased agar invasion C. albicans orf19.2629 ORF USO1 CAL0003416 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.2630 ORF RAD59 CAL0003425 PMID: 20206282|CGD_REF: CAL0125104 homozygous diploid, classical genetics null rad59::hisG/rad59::hisG-URA3-hisG CAI-4 viable C. albicans orf19.2630 ORF RAD59 CAL0003425 PMID: 20206282|CGD_REF: CAL0125104 heterozygous diploid, classical genetics null rad59::hisG-URA3-hisG CAI-4 UV resistance: decreased C. albicans orf19.2630 ORF RAD59 CAL0003425 PMID: 20206282|CGD_REF: CAL0125104 homozygous diploid, classical genetics null rad59::hisG/rad59::hisG-URA3-hisG CAI-4 UV resistance: decreased C. albicans orf19.2630 ORF RAD59 CAL0003425 PMID: 20206282|CGD_REF: CAL0125104 homozygous diploid, classical genetics null rad59::hisG/rad59::hisG-URA3-hisG CAI-4 resistance to chemicals: decreased camptothecin C. albicans orf19.2633 ORF HGT14 CAL0003431 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.2637 ORF CAL0003439 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.2640 ORF FUR1 CAL0003450 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, competitive growth (haploinsufficient phenotype assay, barcode deletion set) null SC5314 resistance to chemicals: increased 5-fluorouracil C. albicans orf19.2640 ORF FUR1 CAL0003450 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, classical genetics repressible SC5314 resistance to chemicals: increased 5-fluorouracil C. albicans orf19.2640 ORF FUR1 CAL0003450 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, competitive growth (haploinsufficient phenotype assay, barcode deletion set) null SC5314 resistance to chemicals: increased flucytosine C. albicans orf19.2640 ORF FUR1 CAL0003450 PMID: 15155225|CGD_REF: CAL0081317 heterozygous diploid, classical genetics unspecified Not recorded resistance to chemicals: increased flucytosine C. albicans orf19.2640 ORF FUR1 CAL0003450 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, classical genetics repressible SC5314 resistance to chemicals: increased flucytosine C. albicans orf19.2640 ORF FUR1 CAL0003450 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.2640 ORF FUR1 CAL0003450 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, competitive growth (haploinsufficient phenotype assay, barcode deletion set) null SC5314 resistance to chemicals: increased 6-azauracil C. albicans orf19.2640 ORF FUR1 CAL0003450 PMID: 15504867|CGD_REF: CAL0082142 unknown ploidy, classical genetics unspecified Other C. albicans resistance to chemicals: increased flucytosine R101C allele is associated with resistance to flucytosine (5-FC) in clinical isolates (but does not definitively cause resistance in all cases); mutation may destabilize intersubunit contacts within the tetramer C. albicans orf19.2640 ORF FUR1 CAL0003450 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient SLAD medium C. albicans orf19.2641 ORF ARP1 CAL0003452 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.2643 ORF RPO26 CAL0003456 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.2643 ORF RPO26 CAL0003456 PMID: 19623926|CGD_REF: CAL0124054 heterozygous diploid, competitive growth (haploinsufficient phenotype assay, barcode deletion set) null SC5314 resistance to chemicals: increased parnafungin C. albicans orf19.2644 ORF QCR2 CAL0003458 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.2644 ORF QCR2 CAL0003458 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 invasive growth: decreased solid SLAD media C. albicans orf19.2646 ORF ZCF13 CAL0003461 PMID: 14663094|CGD_REF: CAL0080633 homozygous diploid, systematic mutation set (homozygous insertion mutants generated with URA3-ARG4-URA3 (UAU1) cassette) null BWP17 viable C. albicans orf19.2646 ORF ZCF13 CAL0003461 PMID: 22073120|CGD_REF: CAL0000143592 homozygous diploid, classical genetics null BWP17 viable C. albicans orf19.2646 ORF ZCF13 CAL0003461 PMID: 22073120|CGD_REF: CAL0000143592 homozygous diploid, classical genetics null BWP17 heat sensitivity: decreased Increased susceptibility to 42 degrees C heat C. albicans orf19.2646 ORF ZCF13 CAL0003461 PMID: 22073120|CGD_REF: CAL0000143592 homozygous diploid, classical genetics null BWP17 viable C. albicans orf19.2646 ORF ZCF13 CAL0003461 PMID: 22073120|CGD_REF: CAL0000143592 homozygous diploid, classical genetics null BWP17 invasive growth: increased increased agar invasion C. albicans orf19.2646 ORF ZCF13 CAL0003461 PMID: 22073120|CGD_REF: CAL0000143592 homozygous diploid, classical genetics null BWP17 viable C. albicans orf19.2646 ORF ZCF13 CAL0003461 PMID: 22073120|CGD_REF: CAL0000143592 homozygous diploid, classical genetics null BWP17 colony appearance: abnormal increased colony wrinkling C. albicans orf19.2647 ORF ZCF14 CAL0003462 PMID: 15964282|CGD_REF: CAL0114274 homozygous diploid, systematic mutation set (split-marker transposon insertion strategy to disrupt both alleles) null BWP17 viable C. albicans orf19.2647 ORF ZCF14 CAL0003462 PMID: 19463063|CGD_REF: CAL0123630 homozygous diploid, systematic mutation set (split-marker transposon insertion strategy to disrupt both alleles) null BWP17 viable C. albicans orf19.2647 ORF ZCF14 CAL0003462 PMID: 15964282|CGD_REF: CAL0114274 homozygous diploid, systematic mutation set (split-marker transposon insertion strategy to disrupt both alleles) null BWP17 biofilm formation: normal C. albicans orf19.2647 ORF ZCF14 CAL0003462 PMID: 22073120|CGD_REF: CAL0000143592 homozygous diploid, classical genetics null BWP17 hyphal growth: decreased C. albicans orf19.2647 ORF ZCF14 CAL0003462 PMID: 19463063|CGD_REF: CAL0123630 homozygous diploid, systematic mutation set (split-marker transposon insertion strategy to disrupt both alleles) null BWP17 virulence: normal Toll mutant D. melanogaster invasive infection insect infection C. albicans orf19.2649 ORF PCL1 CAL0003463 PMID: 22365851|CGD_REF: CAL0000144076 homozygous diploid, classical genetics null pcl1::FRT/pcl1::FRT SN95 invasive growth: decreased grown on YPD agar for 4 days at 42 degrees C, then washed with water required for agar invasion at elevated temperature C. albicans orf19.2649 ORF PCL1 CAL0003463 PMID: 22365851|CGD_REF: CAL0000144076 homozygous diploid, classical genetics null pcl1::FRT/pcl1::FRT SN95 viable C. albicans orf19.2649 ORF PCL1 CAL0003463 PMID: 22365851|CGD_REF: CAL0000144076 homozygous diploid, classical genetics null pcl1::FRT/pcl1::FRT SN95 colony appearance: abnormal required for wrinkly colony morphology at elevated temperature C. albicans orf19.2649 ORF PCL1 CAL0003463 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 invasive growth: decreased solid SLAD media C. albicans orf19.2651 ORF CAM1-1 CAL0003469 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.2653 ORF CAL0003472 PMID: 14663094|CGD_REF: CAL0080633 homozygous diploid, systematic mutation set (homozygous insertion mutants generated with URA3-ARG4-URA3 (UAU1) cassette) null BWP17 viable C. albicans orf19.2653 ORF CAL0003472 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: decreased growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.2653 ORF CAL0003472 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.2653 ORF CAL0003472 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.2653 ORF CAL0003472 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.2655 ORF BUB3 CAL0003474 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.2660 ORF EAF3 CAL0003490 PMID: 14663094|CGD_REF: CAL0080633 homozygous diploid, systematic mutation set (homozygous insertion mutants generated with URA3-ARG4-URA3 (UAU1) cassette) null BWP17 viable C. albicans orf19.2663 ORF CAL0003492 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.2663 ORF CAL0003492 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.2663 ORF CAL0003492 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.2663 ORF CAL0003492 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.2667 ORF RPF1 CAL0003496 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.2667 ORF RPF1 CAL0003496 PMID: 14507372|CGD_REF: CAL0088818 heterozygous diploid, large-scale survey (large-scale identification of essential genes by gene replacement and conditional expression (GRACE) method) repressible CAI-4 inviable one allele is deleted and the other is placed under repressible Tet promoter C. albicans orf19.267 ORF CAL0004042 PMID: 19779551|CGD_REF: CAL0124331 homozygous diploid, classical genetics null CAF2-1 hyphal growth: abnormal serum-containing medium at 37 deg C C. albicans orf19.267 ORF CAL0004042 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.267 ORF CAL0004042 PMID: 19779551|CGD_REF: CAL0124331 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.267 ORF CAL0004042 PMID: 19779551|CGD_REF: CAL0124331 homozygous diploid, classical genetics null Not recorded colony appearance: abnormal solid Spider medium C. albicans orf19.267 ORF CAL0004042 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.267 ORF CAL0004042 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.267 ORF CAL0004042 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.267 ORF CAL0004042 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.2670 ORF CAL0003509 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient SLAD medium C. albicans orf19.2672 ORF NCP1 CAL0003511 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.2672 ORF NCP1 CAL0003511 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, competitive growth (haploinsufficient phenotype assay, barcode deletion set) null SC5314 resistance to chemicals: decreased fluconazole C. albicans orf19.2672 ORF NCP1 CAL0003511 PMID: 20494978|CGD_REF: CAL0125636 heterozygous diploid, classical genetics null BWP17 resistance to chemicals: decreased clotrimazole (75 uM) growth in liquid culture confirmation of mutant phenotypes for heterozygous transposon insertion strains showing sensitivity in a large-scale assay C. albicans orf19.2674 ORF CAL0003513 PMID: 15964282|CGD_REF: CAL0114274 homozygous diploid, systematic mutation set (split-marker transposon insertion strategy to disrupt both alleles) null BWP17 viable C. albicans orf19.2674 ORF CAL0003513 PMID: 15964282|CGD_REF: CAL0114274 homozygous diploid, systematic mutation set (split-marker transposon insertion strategy to disrupt both alleles) null BWP17 biofilm formation: normal C. albicans orf19.2675 ORF CAL0003514 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.2676 ORF CAL0003515 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.2677 ORF CAL0003516 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.2677 ORF CAL0003516 PMID: 21135205|CGD_REF: CAL0139967 heterozygous diploid, large-scale survey (large-scale identification of genes essential for virulence in mouse) repressible CAI-4 virulence: absent mouse intravenous infection C. albicans orf19.2678 ORF BUB1 CAL0003517 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.2678 ORF BUB1 CAL0003517 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, competitive growth (haploinsufficient phenotype assay, barcode deletion set) null SC5314 resistance to chemicals: decreased ECC220 (microtubule inhibitor) C. albicans orf19.2678 ORF BUB1 CAL0003517 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, competitive growth (haploinsufficient phenotype assay, barcode deletion set) null SC5314 resistance to chemicals: decreased nocodazole C. albicans orf19.268 ORF CAL0004044 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.268 ORF CAL0004044 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.268 ORF CAL0004044 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.268 ORF CAL0004044 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.2681 ORF RBT7 CAL0003529 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.2682 ORF CAL0003530 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.2684 ORF CAL0003531 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient YNB medium C. albicans orf19.2685 ORF PGA54 CAL0003532 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 invasive growth: decreased solid SLAD media C. albicans orf19.2686 ORF CAL0003533 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.2686 ORF CAL0003533 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.2686 ORF CAL0003533 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.2686 ORF CAL0003533 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.2687.1 ORF CAF0006961 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.2687.1 ORF CAF0006961 PMID: 21135205|CGD_REF: CAL0139967 heterozygous diploid, competitive growth (large-scale identification of genes essential for virulence in mouse) repressible CAI-4 virulence: decreased mouse intravenous infection C. albicans orf19.2688 ORF NAN1 CAL0003534 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.2688 ORF NAN1 CAL0003534 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 invasive growth: decreased solid SLAD media C. albicans orf19.2688 ORF NAN1 CAL0003534 PMID: 21135205|CGD_REF: CAL0139967 heterozygous diploid, competitive growth (large-scale identification of genes essential for virulence in mouse) repressible CAI-4 virulence: decreased mouse intravenous infection C. albicans orf19.269 ORF SES1 CAL0004049 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.2690 ORF CAL0003545 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.2694 ORF TYS1 CAL0003549 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.2695 ORF UBR1 CAL0003550 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.2695 ORF UBR1 CAL0003550 PMID: 12773383|CGD_REF: CAL0087974 heterozygous diploid, classical genetics (haploinsufficient phenotype assay) unspecified CAI-4 filamentous growth: abnormal solid Spider medium or solid YEPD plus serum decreased or increased filamentous growth, depending on the allele; transposon insertion proximal to, but not within, the ORF C. albicans orf19.2695 ORF UBR1 CAL0003550 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.2695 ORF UBR1 CAL0003550 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: abnormal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.2695 ORF UBR1 CAL0003550 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.2695 ORF UBR1 CAL0003550 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.2697 ORF CAL0003551 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.2697 ORF CAL0003551 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.2697 ORF CAL0003551 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: abnormal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.2697 ORF CAL0003551 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: decreased rate liquid synthetic complete medium C. albicans orf19.2697 ORF CAL0003551 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.2699 ORF ABP1 CAL0003553 PMID: 17431925|CGD_REF: CAL0117929 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.2699 ORF ABP1 CAL0003553 PMID: 17431925|CGD_REF: CAL0117929 homozygous diploid, classical genetics null Not recorded cellular morphology: normal no defects in polarized growth detected C. albicans orf19.2699 ORF ABP1 CAL0003553 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.2699 ORF ABP1 CAL0003553 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.2699 ORF ABP1 CAL0003553 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.2699 ORF ABP1 CAL0003553 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.2703 ORF CAL0004165 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.2703 ORF CAL0004165 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.2703 ORF CAL0004165 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.2703 ORF CAL0004165 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.2706 ORF CRH11 CAL0004169 PMID: 17074760|CGD_REF: CAL0117089 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.2706 ORF CRH11 CAL0004169 PMID: 17074760|CGD_REF: CAL0117089 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased Congo Red C. albicans orf19.2708 ORF CAL0004172 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.2708 ORF CAL0004172 PMID: 16607011|CGD_REF: CAL0115846 heterozygous diploid, classical genetics null SC5314 viable C. albicans orf19.2708 ORF CAL0004172 PMID: 16607011|CGD_REF: CAL0115846 homozygous diploid, classical genetics null SC5314 viable C. albicans orf19.2708 ORF CAL0004172 PMID: 16607011|CGD_REF: CAL0115846 heterozygous diploid, classical genetics repressible SC5314 viable C. albicans orf19.2709 ORF ZUO1 CAL0004174 PMID: 12524333|CGD_REF: CAL0080691 homozygous diploid, systematic mutation set (homozygous insertion mutants generated with URA3-ARG4-URA3 (UAU1) cassette) null BWP17 inviable homozygous null mutant strain could not be recovered, suggesting that the gene is essential under the selection conditions C. albicans orf19.271 ORF ADH4 CAL0004056 PMID: 14663094|CGD_REF: CAL0080633 homozygous diploid, systematic mutation set (homozygous insertion mutants generated with URA3-ARG4-URA3 (UAU1) cassette) null BWP17 viable C. albicans orf19.2711 ORF CAL0004181 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.2711.1 ORF MED20 CAF0006963 PMID: 22496666|CGD_REF: CAL0000157144 homozygous diploid, classical genetics null BWP17 viable C. albicans orf19.2711.1 ORF MED20 CAF0006963 PMID: 22496666|CGD_REF: CAL0000157144 homozygous diploid, classical genetics null BWP17 biofilm formation: decreased C. albicans orf19.2711.1 ORF MED20 CAF0006963 PMID: 22496666|CGD_REF: CAL0000157144 homozygous diploid, classical genetics null BWP17 resistance to chemicals: decreased Congo Red C. albicans orf19.2711.1 ORF MED20 CAF0006963 PMID: 22496666|CGD_REF: CAL0000157144 homozygous diploid, classical genetics null BWP17 resistance to chemicals: decreased sodium dodecyl sulfate C. albicans orf19.2711.1 ORF MED20 CAF0006963 PMID: 22496666|CGD_REF: CAL0000157144 homozygous diploid, classical genetics null BWP17 resistance to chemicals: decreased ethanol C. albicans orf19.2711.1 ORF MED20 CAF0006963 PMID: 23873866|CGD_REF: CAL0000172574 homozygous diploid, classical genetics null SN152 phenotypic switching: abnormal C. albicans orf19.2711.1 ORF MED20 CAF0006963 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 invasive growth: decreased solid SLAD media C. albicans orf19.2712 ORF HCA4 CAL0004182 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.2713 ORF CAL0004183 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.2713 ORF CAL0004183 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient SC medium C. albicans orf19.2713 ORF CAL0004183 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient YNB medium C. albicans orf19.2713 ORF CAL0004183 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient SLAD medium C. albicans orf19.2715 ORF RPC53 CAL0004186 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.2717 ORF SAS10 CAL0004189 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, competitive growth (haploinsufficient phenotype assay, barcode deletion set) null SC5314 resistance to chemicals: increased flucytosine C. albicans orf19.2717 ORF SAS10 CAL0004189 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.2717 ORF SAS10 CAL0004189 PMID: 21135205|CGD_REF: CAL0139967 heterozygous diploid, large-scale survey (large-scale identification of genes essential for virulence in mouse) repressible CAI-4 virulence: absent mouse intravenous infection C. albicans orf19.272 ORF FAA21 CAL0004057 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.272 ORF FAA21 CAL0004057 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient YPD medium C. albicans orf19.272 ORF FAA21 CAL0004057 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient SC medium C. albicans orf19.272 ORF FAA21 CAL0004057 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient YNB medium C. albicans orf19.2720 ORF CAL0004195 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.2720 ORF CAL0004195 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient SLAD medium C. albicans orf19.2721 ORF CAL0004196 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.2722 ORF CGR1 CAL0004197 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.2723 ORF HIT1 CAL0004198 PMID: 16939537|CGD_REF: CAL0117180 homozygous diploid, classical genetics null Not recorded heat sensitivity: increased C. albicans orf19.2723 ORF HIT1 CAL0004198 PMID: 14663094|CGD_REF: CAL0080633 homozygous diploid, systematic mutation set (homozygous insertion mutants generated with URA3-ARG4-URA3 (UAU1) cassette) null BWP17 viable C. albicans orf19.2723 ORF HIT1 CAL0004198 PMID: 16939537|CGD_REF: CAL0117180 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.2723 ORF HIT1 CAL0004198 PMID: 23856128|CGD_REF: CAL0000172540 homozygous diploid, classical genetics null BWP17 resistance to chemicals: decreased propolis C. albicans orf19.2726 ORF CAL0004202 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: increased growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.2726 ORF CAL0004202 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.2726 ORF CAL0004202 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.2726 ORF CAL0004202 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.2727 ORF GRX3 CAL0004203 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.2733 ORF CAL0004212 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.2733 ORF CAL0004212 PMID: 20494978|CGD_REF: CAL0125636 heterozygous diploid, classical genetics null BWP17 resistance to chemicals: decreased clotrimazole (75 uM) growth in liquid culture confirmation of mutant phenotypes for heterozygous transposon insertion strains showing sensitivity in a large-scale assay C. albicans orf19.2734 ORF CAL0004213 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.2734 ORF CAL0004213 PMID: 14663094|CGD_REF: CAL0080633 homozygous diploid, systematic mutation set (homozygous insertion mutants generated with URA3-ARG4-URA3 (UAU1) cassette) null BWP17 viable C. albicans orf19.2735 ORF SEN2 CAL0004215 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.2735 ORF SEN2 CAL0004215 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, competitive growth (haploinsufficient phenotype assay, barcode deletion set) null SC5314 resistance to chemicals: decreased amphotericin B C. albicans orf19.2735 ORF SEN2 CAL0004215 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, competitive growth (haploinsufficient phenotype assay, barcode deletion set) null SC5314 resistance to chemicals: decreased ergosterol analogs (ECC69 and/or ECC1384) C. albicans orf19.2735 ORF SEN2 CAL0004215 PMID: 21135205|CGD_REF: CAL0139967 heterozygous diploid, competitive growth (large-scale identification of genes essential for virulence in mouse) repressible CAI-4 virulence: decreased mouse intravenous infection C. albicans orf19.2736 ORF HFL2 CAL0004217 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.2738 ORF SUL2 CAL0004221 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.2739 ORF CAL0004223 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.274 ORF TFC4 CAL0004061 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.2743 ORF CAL0004229 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 invasive growth: decreased solid SLAD media C. albicans orf19.2745 ORF UME7 CAL0004230 PMID: 17555439|CGD_REF: CAL0117968 homozygous diploid, classical genetics null Not recorded survival rate in stationary phase: decreased C. albicans orf19.2745 ORF UME7 CAL0004230 PMID: 15964282|CGD_REF: CAL0114274 homozygous diploid, systematic mutation set (split-marker transposon insertion strategy to disrupt both alleles) null BWP17 viable C. albicans orf19.2745 ORF UME7 CAL0004230 PMID: 19463063|CGD_REF: CAL0123630 homozygous diploid, systematic mutation set (split-marker transposon insertion strategy to disrupt both alleles) null BWP17 viable C. albicans orf19.2745 ORF UME7 CAL0004230 PMID: 15964282|CGD_REF: CAL0114274 homozygous diploid, systematic mutation set (split-marker transposon insertion strategy to disrupt both alleles) null BWP17 biofilm formation: normal C. albicans orf19.2745 ORF UME7 CAL0004230 PMID: 19463063|CGD_REF: CAL0123630 homozygous diploid, systematic mutation set (split-marker transposon insertion strategy to disrupt both alleles) null BWP17 virulence: normal Toll mutant D. melanogaster invasive infection insect infection C. albicans orf19.2747 ORF RGT1 CAL0004232 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.2747 ORF RGT1 CAL0004232 PMID: 17605131|CGD_REF: CAL0118478 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.2747 ORF RGT1 CAL0004232 PMID: 17605131|CGD_REF: CAL0118478 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased 2-deoxy-D-glucose C. albicans orf19.2747 ORF RGT1 CAL0004232 PMID: 20041210|CGD_REF: CAL0124764 homozygous diploid, systematic mutation set null SN152 colony appearance: abnormal YEPD medium at 42 deg C strongly decreased colony fuzziness and/or peripheral filamentation C. albicans orf19.2747 ORF RGT1 CAL0004232 PMID: 17605131|CGD_REF: CAL0118478 homozygous diploid, classical genetics null BWP17 filamentous growth: increased C. albicans orf19.2747 ORF RGT1 CAL0004232 PMID: 19249212|CGD_REF: CAL0122456 homozygous diploid, classical genetics null BWP17 filamentous growth: increased Spider medium at 37 deg C C. albicans orf19.2747 ORF RGT1 CAL0004232 PMID: 22073120|CGD_REF: CAL0000143592 homozygous diploid, classical genetics null BWP17 hyphal growth: decreased C. albicans orf19.2748 ORF ARG83 CAL0004233 PMID: 20041210|CGD_REF: CAL0124764 homozygous diploid, systematic mutation set null SN152 acid pH resistance: decreased pH 2.0 strongly sensitive C. albicans orf19.2748 ORF ARG83 CAL0004233 PMID: 20041210|CGD_REF: CAL0124764 homozygous diploid, systematic mutation set null SN152 utilization of nitrogen source: decreased proline strongly decreased C. albicans orf19.2748 ORF ARG83 CAL0004233 PMID: 20041210|CGD_REF: CAL0124764 homozygous diploid, systematic mutation set null SN152 colony appearance: abnormal Lee's medium pH 6.8 at 37 deg C strongly decreased colony fuzziness and/or peripheral filamentation C. albicans orf19.2749 ORF CAL0004234 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.275 ORF CAL0004064 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.2752 ORF ADR1 CAL0004236 PMID: 19700635|CGD_REF: CAL0124154 homozygous diploid, classical genetics null Not recorded utilization of carbon source: normal extra-virgin olive oil C. albicans orf19.2752 ORF ADR1 CAL0004236 PMID: 12773383|CGD_REF: CAL0087974 heterozygous diploid, classical genetics (haploinsufficient phenotype assay) null CAI-4 viable heterozygous transposon insertion C. albicans orf19.2752 ORF ADR1 CAL0004236 PMID: 19700635|CGD_REF: CAL0124154 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.2752 ORF ADR1 CAL0004236 PMID: 15964282|CGD_REF: CAL0114274 homozygous diploid, systematic mutation set (split-marker transposon insertion strategy to disrupt both alleles) null BWP17 inviable homozygous null mutant strain could not be recovered, suggesting that the gene is essential under the selection conditions C. albicans orf19.2752 ORF ADR1 CAL0004236 PMID: 19700635|CGD_REF: CAL0124154 homozygous diploid, classical genetics null Not recorded utilization of carbon source: normal acetic acid C. albicans orf19.2752 ORF ADR1 CAL0004236 PMID: 19700635|CGD_REF: CAL0124154 homozygous diploid, classical genetics null Not recorded utilization of carbon source: normal oleic acid C. albicans orf19.2752 ORF ADR1 CAL0004236 PMID: 19700635|CGD_REF: CAL0124154 homozygous diploid, classical genetics null Not recorded utilization of carbon source: normal ethanol C. albicans orf19.2752 ORF ADR1 CAL0004236 PMID: 19700635|CGD_REF: CAL0124154 homozygous diploid, classical genetics null Not recorded utilization of carbon source: normal linoleic acid C. albicans orf19.2752 ORF ADR1 CAL0004236 PMID: 19700635|CGD_REF: CAL0124154 homozygous diploid, classical genetics null Not recorded utilization of carbon source: normal glycerol C. albicans orf19.2752 ORF ADR1 CAL0004236 PMID: 12773383|CGD_REF: CAL0087974 heterozygous diploid, classical genetics (haploinsufficient phenotype assay) null CAI-4 filamentous growth: increased solid Spider medium heterozygous transposon insertion C. albicans orf19.2752 ORF ADR1 CAL0004236 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.2752 ORF ADR1 CAL0004236 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: abnormal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.2752 ORF ADR1 CAL0004236 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.2752 ORF ADR1 CAL0004236 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.2753 ORF ZCF15 CAL0004237 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.2753 ORF ZCF15 CAL0004237 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.2753 ORF ZCF15 CAL0004237 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.2753 ORF ZCF15 CAL0004237 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.2753 ORF ZCF15 CAL0004237 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.2755 ORF CAL0004239 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.2756 ORF CAL0004240 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.2756 ORF CAL0004240 PMID: 21135205|CGD_REF: CAL0139967 heterozygous diploid, large-scale survey (large-scale identification of genes essential for virulence in mouse) repressible CAI-4 virulence: absent mouse intravenous infection C. albicans orf19.2758 ORF PGA38 CAL0004242 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.2758 ORF PGA38 CAL0004242 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 invasive growth: decreased solid SLAD media C. albicans orf19.2760 ORF CAL0004251 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.2760 ORF CAL0004251 PMID: 19623926|CGD_REF: CAL0124054 heterozygous diploid, competitive growth (haploinsufficient phenotype assay, barcode deletion set) null SC5314 resistance to chemicals: decreased parnafungin C. albicans orf19.2760 ORF CAL0004251 PMID: 19623926|CGD_REF: CAL0124054 heterozygous diploid, competitive growth (haploinsufficient phenotype assay, barcode deletion set) null SC5314 resistance to chemicals: decreased cordycepin C. albicans orf19.2760 ORF CAL0004251 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 invasive growth: decreased solid SLAD media C. albicans orf19.2761 ORF CAL0004252 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.2761 ORF CAL0004252 PMID: 20141603|CGD_REF: CAL0124951 homozygous diploid, systematic mutation set (homozygous insertion mutants generated with URA3-ARG4-URA3 (UAU1) cassette) null BWP17 colony appearance: abnormal 10% serum or Spider media at 37 deg C colonies are smoother than wild type but mutant is able to form true hyphae under liquid inducing conditions C. albicans orf19.2761 ORF CAL0004252 PMID: 20141603|CGD_REF: CAL0124951 homozygous diploid, systematic mutation set (homozygous insertion mutants generated with URA3-ARG4-URA3 (UAU1) cassette) null BWP17 viable C. albicans orf19.2762 ORF AHP1 CAL0004253 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.2763 ORF CAL0004254 PMID: 14663094|CGD_REF: CAL0080633 homozygous diploid, systematic mutation set (homozygous insertion mutants generated with URA3-ARG4-URA3 (UAU1) cassette) null BWP17 viable C. albicans orf19.2765 ORF PGA62 CAL0004255 PMID: 18765290|CGD_REF: CAL0119430 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased Calcofluor White C. albicans orf19.2765 ORF PGA62 CAL0004255 PMID: 18765290|CGD_REF: CAL0119430 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.2765 ORF PGA62 CAL0004255 PMID: 19383685|CGD_REF: CAL0122757 homozygous diploid, classical genetics null BWP17 biofilm formation: normal C. albicans orf19.2765 ORF PGA62 CAL0004255 PMID: 18765290|CGD_REF: CAL0119430 homozygous diploid, classical genetics null Not recorded cell wall morphology: abnormal increased thickness of central chitin/glucan layer C. albicans orf19.2765 ORF PGA62 CAL0004255 PMID: 18765290|CGD_REF: CAL0119430 homozygous diploid, classical genetics null Not recorded chitin deposition: increased C. albicans orf19.2765 ORF PGA62 CAL0004255 PMID: 18765290|CGD_REF: CAL0119430 homozygous diploid, classical genetics null Not recorded resistance to chemicals: increased caspofungin C. albicans orf19.2765 ORF PGA62 CAL0004255 PMID: 19383685|CGD_REF: CAL0122757 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased Congo Red C. albicans orf19.2765 ORF PGA62 CAL0004255 PMID: 18765290|CGD_REF: CAL0119430 homozygous diploid, classical genetics null Not recorded chemical compound accumulation: increased glucan increased cell wall glucan C. albicans orf19.2767 ORF PGA59 CAL0004257 PMID: 19383685|CGD_REF: CAL0122757 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.2767 ORF PGA59 CAL0004257 PMID: 19383685|CGD_REF: CAL0122757 homozygous diploid, classical genetics null BWP17 biofilm formation: normal C. albicans orf19.2767 ORF PGA59 CAL0004257 PMID: 19383685|CGD_REF: CAL0122757 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased Congo Red C. albicans orf19.2767 ORF PGA59 CAL0004257 PMID: 19383685|CGD_REF: CAL0122757 homozygous diploid, classical genetics null BWP17 filamentous growth: decreased liquid Lee's medium severe decrease C. albicans orf19.2768 ORF AMS1 CAL0004258 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.2768 ORF AMS1 CAL0004258 PMID: 19187560|CGD_REF: CAL0122338 homozygous diploid, classical genetics null SC5314 biofilm formation: abnormal forms biofilm with altered detachment properties C. albicans orf19.277 ORF THI6 CAL0004069 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.2770 ORF CAL0004268 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 invasive growth: decreased solid SLAD media C. albicans orf19.2770.1 ORF SOD1 CAL0006717 PMID: 12898709|CGD_REF: CAL0081932 homozygous diploid, classical genetics null Not recorded oxidative stress resistance: increased lithium chloride C. albicans orf19.2770.1 ORF SOD1 CAL0006717 PMID: 12427960|CGD_REF: CAL0081929 homozygous diploid, classical genetics null CAI-4 hyphal growth: delayed Spider medium C. albicans orf19.2770.1 ORF SOD1 CAL0006717 PMID: 19019164|CGD_REF: CAL0121070 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.2770.1 ORF SOD1 CAL0006717 PMID: 19019164|CGD_REF: CAL0121070 homozygous diploid, classical genetics null Not recorded interaction with host/environment: normal wild-type reactive oxygen species accumulation during response to macrophages in vitro model of infection C. albicans orf19.2770.1 ORF SOD1 CAL0006717 PMID: 12427960|CGD_REF: CAL0081929 homozygous diploid, classical genetics null Not recorded oxidative stress resistance: normal hydrogen peroxide C. albicans orf19.2770.1 ORF SOD1 CAL0006717 PMID: 12898709|CGD_REF: CAL0081932 homozygous diploid, classical genetics null Not recorded oxidative stress resistance: increased diamide C. albicans orf19.2770.1 ORF SOD1 CAL0006717 PMID: 19019164|CGD_REF: CAL0121070 homozygous diploid, classical genetics null Not recorded oxidative stress resistance: increased diamide C. albicans orf19.2770.1 ORF SOD1 CAL0006717 PMID: 19019164|CGD_REF: CAL0121070 homozygous diploid, classical genetics null Not recorded oxidative stress resistance: increased diamide C. albicans orf19.2770.1 ORF SOD1 CAL0006717 PMID: 12427960|CGD_REF: CAL0081929 homozygous diploid, classical genetics null Not recorded oxidative stress resistance: decreased menadione C. albicans orf19.2770.1 ORF SOD1 CAL0006717 PMID: 19019164|CGD_REF: CAL0121070 homozygous diploid, classical genetics null Not recorded oxidative stress resistance: decreased menadione C. albicans orf19.2770.1 ORF SOD1 CAL0006717 PMID: 19019164|CGD_REF: CAL0121070 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased menadione C. albicans orf19.2770.1 ORF SOD1 CAL0006717 PMID: 12427960|CGD_REF: CAL0081929 homozygous diploid, classical genetics null CAI-4 viable C. albicans orf19.2770.1 ORF SOD1 CAL0006717 PMID: 12427960|CGD_REF: CAL0081929 homozygous diploid, classical genetics null CAI-4 viable L-lysine leaky auxotrophy: slow growth in the absence of lysine C. albicans orf19.2770.1 ORF SOD1 CAL0006717 PMID: 12427960|CGD_REF: CAL0081929 homozygous diploid, classical genetics null CAI-4 virulence: decreased mouse intravenous infection (17-20g BALB/c mice) C. albicans orf19.2770.1 ORF SOD1 CAL0006717 PMID: 12427960|CGD_REF: CAL0081929 homozygous diploid, classical genetics null CAI-4 resistance to killing by host cells: decreased in vitro model of infection (RAW264.7 macrophages) C. albicans orf19.2771 ORF BEM3 CAL0004269 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.2771 ORF BEM3 CAL0004269 PMID: 17093060|CGD_REF: CAL0117112 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.2771 ORF BEM3 CAL0004269 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.2771 ORF BEM3 CAL0004269 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.2771 ORF BEM3 CAL0004269 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: decreased rate liquid synthetic complete medium C. albicans orf19.2771 ORF BEM3 CAL0004269 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.2772 ORF HOS3 CAL0004270 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.2772 ORF HOS3 CAL0004270 PMID: 19555456|CGD_REF: CAL0123821 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.2775 ORF IDI1 CAL0004272 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.2778 ORF CAL0004274 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.278 ORF CAL0004072 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.278 ORF CAL0004072 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.278 ORF CAL0004072 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.278 ORF CAL0004072 PMID: 23572557|CGD_REF: CAL0000158900 homozygous diploid, classical genetics null BWP17 adhesion: decreased Fluxion Bioflux 200, equipped with a microscope, was used for adherence analysis allowing a constant flow of cells through microfluidic channels C. albicans orf19.278 ORF CAL0004072 PMID: 23572557|CGD_REF: CAL0000158900 homozygous diploid, classical genetics null BWP17 resistance to chemicals: increased fluconazole RPMI+MOPS+Histidine medium , 6 hours without shaking at 37 degrees C 24 hr fluconazole treatment in 96 well plates C. albicans orf19.278 ORF CAL0004072 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.278 ORF CAL0004072 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.2781 ORF CAL0004285 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.2781 ORF CAL0004285 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.2781 ORF CAL0004285 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.2781 ORF CAL0004285 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient YPD medium C. albicans orf19.2781 ORF CAL0004285 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.2783 ORF PIR32 CAL0004287 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.2783 ORF PIR32 CAL0004287 PMID: 22391823|CGD_REF: CAL0000144107 homozygous diploid, classical genetics null pir32::HIS1/pir32::URA3 RM1000 viable C. albicans orf19.2783 ORF PIR32 CAL0004287 PMID: 22391823|CGD_REF: CAL0000144107 homozygous diploid, classical genetics null pir32::HIS1/pir32::URA3 RM1000 filamentous growth: increased C. albicans orf19.2783 ORF PIR32 CAL0004287 PMID: 22391823|CGD_REF: CAL0000144107 homozygous diploid, classical genetics null pir32::HIS1/pir32::URA3 RM1000 virulence: increased mouse intravenous infection C. albicans orf19.2783 ORF PIR32 CAL0004287 PMID: 22391823|CGD_REF: CAL0000144107 homozygous diploid, classical genetics null pir32::HIS1/pir32::URA3 RM1000 oxidative stress resistance: increased hydrogen peroxide C. albicans orf19.2783 ORF PIR32 CAL0004287 PMID: 22391823|CGD_REF: CAL0000144107 homozygous diploid, classical genetics null pir32::HIS1/pir32::URA3 RM1000 resistance to chemicals: increased sodium dodecyl sulfate C. albicans orf19.2787 ORF PRY1 CAL0004291 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.2787 ORF PRY1 CAL0004291 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.2787 ORF PRY1 CAL0004291 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.2787 ORF PRY1 CAL0004291 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.2787 ORF PRY1 CAL0004291 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.2790 ORF SWD2 CAL0004300 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.2791 ORF BBC1 CAL0004301 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.2791 ORF BBC1 CAL0004301 PMID: 20402797|CGD_REF: CAL0125391 homozygous diploid, classical genetics null Other C. albicans viable C. albicans orf19.2792 ORF IST2 CAL0004302 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.2792 ORF IST2 CAL0004302 PMID: 14507372|CGD_REF: CAL0088818 heterozygous diploid, large-scale survey (large-scale identification of essential genes by gene replacement and conditional expression (GRACE) method) repressible CAI-4 viable one allele is deleted and the other is placed under repressible Tet promoter C. albicans orf19.2794 ORF CAL0004303 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.2796 ORF CAL0004305 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.2796 ORF CAL0004305 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 invasive growth: decreased solid SLAD media C. albicans orf19.2797 ORF CAL0004306 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.2797 ORF CAL0004306 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.2797 ORF CAL0004306 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.2797 ORF CAL0004306 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.2798 ORF CAL0004307 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 invasive growth: decreased solid SLAD media C. albicans orf19.2799 ORF GPI8 CAL0004308 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.2799 ORF GPI8 CAL0004308 PMID: 12524333|CGD_REF: CAL0080691 homozygous diploid, systematic mutation set (homozygous insertion mutants generated with URA3-ARG4-URA3 (UAU1) cassette) null BWP17 inviable homozygous null mutant strain could not be recovered, suggesting that the gene is essential under the selection conditions C. albicans orf19.28 ORF CAL0000526 PMID: 23572557|CGD_REF: CAL0000158900 homozygous diploid, classical genetics null orf19.28::Tn7-UAU1/orf19.28::Tn7-URA3 BWP17 viable C. albicans orf19.2803 ORF HEM13 CAL0005027 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.2805 ORF PEX8 CAL0005030 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: abnormal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.2805 ORF PEX8 CAL0005030 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: decreased rate liquid synthetic complete medium C. albicans orf19.2805 ORF PEX8 CAL0005030 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.2805 ORF PEX8 CAL0005030 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.2808 ORF ZCF16 CAL0005035 PMID: 14663094|CGD_REF: CAL0080633 homozygous diploid, systematic mutation set (homozygous insertion mutants generated with URA3-ARG4-URA3 (UAU1) cassette) null BWP17 viable C. albicans orf19.2808 ORF ZCF16 CAL0005035 PMID: 22073120|CGD_REF: CAL0000143592 homozygous diploid, classical genetics null BWP17 viable C. albicans orf19.2808 ORF ZCF16 CAL0005035 PMID: 22073120|CGD_REF: CAL0000143592 homozygous diploid, classical genetics null BWP17 colony appearance: abnormal increased colony wrinkling C. albicans orf19.2809 ORF CTN3 CAL0005036 PMID: 15219562|CGD_REF: CAL0082066 homozygous diploid, classical genetics null CAI-4 germ tube formation: abnormal within macrophages germ tubes are shorter than wild-type C. albicans orf19.2809 ORF CTN3 CAL0005036 PMID: 15219562|CGD_REF: CAL0082066 heterozygous diploid, classical genetics null CAI-4 germ tube formation: abnormal within macrophages germ tubes are shorter than wild-type; phenotype is intermediate between that of wild type and the homozygous null mutant C. albicans orf19.2809 ORF CTN3 CAL0005036 PMID: 15219562|CGD_REF: CAL0082066 heterozygous diploid, classical genetics null CAI-4 hyphal growth: decreased solid M199 pH 7, ethanol-, glycerol-, or serum-containing media C. albicans orf19.2809 ORF CTN3 CAL0005036 PMID: 15219562|CGD_REF: CAL0082066 homozygous diploid, classical genetics null CAI-4 hyphal growth: decreased solid M199 pH 7, ethanol-, glycerol-, or serum-containing media C. albicans orf19.2809 ORF CTN3 CAL0005036 PMID: 18227254|CGD_REF: CAL0118865 homozygous diploid, classical genetics null SC5314 hyphal growth: normal solid YP-glycerol, YP-serum, or M199, 37 deg C; strain is Ura+ C. albicans orf19.2809 ORF CTN3 CAL0005036 PMID: 18227254|CGD_REF: CAL0118865 homozygous diploid, classical genetics null SC5314 viable strain is Ura+ C. albicans orf19.2809 ORF CTN3 CAL0005036 PMID: 15219562|CGD_REF: CAL0082066 homozygous diploid, classical genetics null CAI-4 viable C. albicans orf19.2809 ORF CTN3 CAL0005036 PMID: 15219562|CGD_REF: CAL0082066 homozygous diploid, classical genetics null CAI-4 resistance to killing by host cells: decreased in vitro model of infection (J774.1 macrophages) C. albicans orf19.2809 ORF CTN3 CAL0005036 PMID: 15219562|CGD_REF: CAL0082066 heterozygous diploid, classical genetics null CAI-4 resistance to killing by host cells: decreased phenotype is intermediate between that of wild type and the homozygous null mutant in vitro model of infection (J774.1 macrophages) C. albicans orf19.2809 ORF CTN3 CAL0005036 PMID: 15219562|CGD_REF: CAL0082066 heterozygous diploid, classical genetics null CAI-4 viable C. albicans orf19.2809 ORF CTN3 CAL0005036 PMID: 18227254|CGD_REF: CAL0118865 homozygous diploid, classical genetics null SC5314 virulence: normal strain is Ura+ mouse intravenous infection C. albicans orf19.2810 ORF AAP1 CAL0005050 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.2810 ORF AAP1 CAL0005050 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 invasive growth: decreased solid SLAD media C. albicans orf19.2818 ORF CAL0005059 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.2820 ORF CAL0005076 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.2821 ORF CAL0005078 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.2821 ORF CAL0005078 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: decreased growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.2821 ORF CAL0005078 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: decreased rate liquid synthetic complete medium C. albicans orf19.2821 ORF CAL0005078 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.2823 ORF RFG1 CAL0005080 PMID: 12773383|CGD_REF: CAL0087974 heterozygous diploid, classical genetics (haploinsufficient phenotype assay) null CAI-4 viable heterozygous deletion C. albicans orf19.2823 ORF RFG1 CAL0005080 PMID: 11259598|CGD_REF: CAL0081162 heterozygous diploid, classical genetics null Not recorded viable C. albicans orf19.2823 ORF RFG1 CAL0005080 PMID: 11259598|CGD_REF: CAL0081162 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.2823 ORF RFG1 CAL0005080 PMID: 11290707|CGD_REF: CAL0081366 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.2823 ORF RFG1 CAL0005080 PMID: 12060662|CGD_REF: CAL0081313 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.2823 ORF RFG1 CAL0005080 PMID: 18424510|CGD_REF: CAL0118975 homozygous diploid, classical genetics null Not recorded interaction with host/environment: normal wild-type response to farnesol C. albicans orf19.2823 ORF RFG1 CAL0005080 PMID: 12773383|CGD_REF: CAL0087974 heterozygous diploid, classical genetics (haploinsufficient phenotype assay) null CAI-4 filamentous growth: increased solid Spider medium or solid YEPD plus serum heterozygous deletion C. albicans orf19.2823 ORF RFG1 CAL0005080 PMID: 12773383|CGD_REF: CAL0087974 heterozygous diploid, classical genetics (haploinsufficient phenotype assay) unspecified CAI-4 filamentous growth: increased solid Spider medium transposon insertion proximal to, but not within, the ORF C. albicans orf19.2823 ORF RFG1 CAL0005080 PMID: 12060662|CGD_REF: CAL0081313 homozygous diploid, classical genetics null Not recorded filamentous growth: abnormal YPD medium at 30 deg C constitutive filamentous growth C. albicans orf19.2823 ORF RFG1 CAL0005080 PMID: 11290707|CGD_REF: CAL0081366 homozygous diploid, classical genetics null Not recorded filamentous growth: increased growth is exclusively filamentous and mostly hyphal C. albicans orf19.2823 ORF RFG1 CAL0005080 PMID: 11259598|CGD_REF: CAL0081162 heterozygous diploid, classical genetics null Not recorded filamentous growth: increased phenotype is intermediate between that of wild type and the homozygous null mutant C. albicans orf19.2823 ORF RFG1 CAL0005080 PMID: 11259598|CGD_REF: CAL0081162 homozygous diploid, classical genetics null Not recorded filamentous growth: increased solid media C. albicans orf19.2823 ORF RFG1 CAL0005080 PMID: 11259598|CGD_REF: CAL0081162 homozygous diploid, classical genetics null Not recorded filamentous growth: decreased solid Spider, serum-containing, Lee's ph 6.8 mannitol, and Lee's ph 4.5 mannitol media C. albicans orf19.2823 ORF RFG1 CAL0005080 PMID: 11259598|CGD_REF: CAL0081162 homozygous diploid, classical genetics null Not recorded virulence: absent mouse intravenous infection C. albicans orf19.2823 ORF RFG1 CAL0005080 PMID: 11259598|CGD_REF: CAL0081162 heterozygous diploid, classical genetics null Not recorded virulence: decreased mouse intravenous infection C. albicans orf19.2823 ORF RFG1 CAL0005080 PMID: 20656914|CGD_REF: CAL0125988 heterozygous diploid, classical genetics overexpression RFG1/rfg1::URA3-tetO-RFG1 CAF2-1 virulence: normal mouse intravenous infection C. albicans orf19.2823 ORF RFG1 CAL0005080 PMID: 20656914|CGD_REF: CAL0125988 heterozygous diploid, classical genetics overexpression RFG1/rfg1::URA3-tetO-RFG1 CAF2-1 pseudohyphal growth: increased C. albicans orf19.2823 ORF RFG1 CAL0005080 PMID: 20656914|CGD_REF: CAL0125988 heterozygous diploid, classical genetics overexpression RFG1/rfg1::URA3-tetO-RFG1 CAF2-1 hyphal growth: normal C. albicans orf19.2825 ORF DRE2 CAL0005083 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.2825 ORF DRE2 CAL0005083 PMID: 21135205|CGD_REF: CAL0139967 heterozygous diploid, competitive growth (large-scale identification of genes essential for virulence in mouse) repressible CAI-4 virulence: normal mouse intravenous infection C. albicans orf19.2827 ORF CAL0005087 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.2828 ORF CAL0005089 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.2830 ORF RRP9 CAL0005106 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, competitive growth (haploinsufficient phenotype assay, barcode deletion set) null SC5314 resistance to chemicals: increased 5-fluorouracil C. albicans orf19.2830 ORF RRP9 CAL0005106 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, competitive growth (haploinsufficient phenotype assay, barcode deletion set) null SC5314 resistance to chemicals: increased tubercidin C. albicans orf19.2830 ORF RRP9 CAL0005106 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, competitive growth (haploinsufficient phenotype assay, barcode deletion set) null SC5314 resistance to chemicals: increased flucytosine C. albicans orf19.2830 ORF RRP9 CAL0005106 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.2831 ORF RPC31 CAL0005108 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.2833 ORF PGA34 CAL0005110 PMID: 21407800|CGD_REF: CAL0141800 homozygous diploid, classical genetics null BWP17 interaction with host/environment: abnormal significantly reduced damage to epithelial cells, but normal adhesion and invasion ex vivo model of infection C. albicans orf19.2834 ORF RPD3 CAL0005111 PMID: 19555456|CGD_REF: CAL0123821 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.2834 ORF RPD3 CAL0005111 PMID: 11443097|CGD_REF: CAL0081194 homozygous diploid, classical genetics null Not recorded phenotypic switching: increased both white-to-opaque and opaque-to-white switching C. albicans orf19.2835 ORF CAL0005113 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.2836 ORF CAL0005115 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.2836 ORF CAL0005115 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.2836 ORF CAL0005115 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.2836 ORF CAL0005115 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.2836 ORF CAL0005115 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.2837 ORF ALG5 CAL0005117 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.2838 ORF CAL0005119 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.2838 ORF CAL0005119 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, competitive growth (haploinsufficient phenotype assay, barcode deletion set) null SC5314 resistance to chemicals: decreased amphotericin B C. albicans orf19.2838 ORF CAL0005119 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.2838 ORF CAL0005119 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.2838 ORF CAL0005119 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.2838 ORF CAL0005119 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.2841 ORF PGM2 CAL0005135 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.2841 ORF PGM2 CAL0005135 PMID: 14663094|CGD_REF: CAL0080633 homozygous diploid, systematic mutation set (homozygous insertion mutants generated with URA3-ARG4-URA3 (UAU1) cassette) null BWP17 viable C. albicans orf19.2842 ORF GZF3 CAL0005136 PMID: 20041210|CGD_REF: CAL0124764 homozygous diploid, systematic mutation set null SN152 resistance to chemicals: decreased fluconazole strongly sensitive C. albicans orf19.2842 ORF GZF3 CAL0005136 PMID: 20041210|CGD_REF: CAL0124764 homozygous diploid, systematic mutation set null SN152 ionic stress resistance: decreased lithium chloride strongly sensitive C. albicans orf19.2842 ORF GZF3 CAL0005136 PMID: 20041210|CGD_REF: CAL0124764 homozygous diploid, systematic mutation set null SN152 heat sensitivity: increased elevated temperature (42 deg C, YEPD or SD medium) strongly sensitive C. albicans orf19.2842 ORF GZF3 CAL0005136 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.2842 ORF GZF3 CAL0005136 PMID: 20041210|CGD_REF: CAL0124764 homozygous diploid, systematic mutation set null SN152 resistance to chemicals: decreased rapamycin strongly sensitive C. albicans orf19.2842 ORF GZF3 CAL0005136 PMID: 20041210|CGD_REF: CAL0124764 homozygous diploid, systematic mutation set null SN152 colony appearance: abnormal Spider medium at 30 deg C increased colony wrinkling and reduced peripheral filamentation C. albicans orf19.2842 ORF GZF3 CAL0005136 PMID: 20041210|CGD_REF: CAL0124764 homozygous diploid, systematic mutation set null SN152 metal resistance: decreased copper(2+) strongly sensitive C. albicans orf19.2842 ORF GZF3 CAL0005136 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: decreased growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.2842 ORF GZF3 CAL0005136 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: abnormal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.2842 ORF GZF3 CAL0005136 PMID: 23856128|CGD_REF: CAL0000172540 homozygous diploid, classical genetics null BWP17 resistance to chemicals: decreased propolis C. albicans orf19.2842 ORF GZF3 CAL0005136 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.2842 ORF GZF3 CAL0005136 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.2843 ORF RHO1 CAL0005137 PMID: 16078083|CGD_REF: CAL0114544 heterozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased Calcofluor White C. albicans orf19.2843 ORF RHO1 CAL0005137 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.2843 ORF RHO1 CAL0005137 PMID: 16078083|CGD_REF: CAL0114544 heterozygous diploid, classical genetics null Not recorded viable C. albicans orf19.2843 ORF RHO1 CAL0005137 PMID: 14507372|CGD_REF: CAL0088818 heterozygous diploid, large-scale survey (large-scale identification of essential genes by gene replacement and conditional expression (GRACE) method) repressible CAI-4 inviable one allele is deleted and the other is placed under repressible Tet promoter C. albicans orf19.2843 ORF RHO1 CAL0005137 PMID: 12702298|CGD_REF: CAL0081726 heterozygous diploid, classical genetics repressible Not recorded inviable C. albicans orf19.2843 ORF RHO1 CAL0005137 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, competitive growth (haploinsufficient phenotype assay, barcode deletion set) null SC5314 resistance to chemicals: decreased caspofungin C. albicans orf19.2843 ORF RHO1 CAL0005137 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, competitive growth (haploinsufficient phenotype assay, barcode deletion set) null SC5314 resistance to chemicals: decreased ergokonin A C. albicans orf19.2843 ORF RHO1 CAL0005137 PMID: 21135205|CGD_REF: CAL0139967 heterozygous diploid, large-scale survey (large-scale identification of genes essential for virulence in mouse) repressible CAI-4 virulence: absent mouse intravenous infection C. albicans orf19.2844 ORF APL4 CAL0005138 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.2847 ORF CAL0005140 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.2848 ORF CAL0005141 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.2849 ORF AQY1 CAL0005142 PMID: 11746601|CGD_REF: CAL0080765 homozygous diploid, classical genetics null CAI-4 flocculation: normal liquid YPD medium C. albicans orf19.2849 ORF AQY1 CAL0005142 PMID: 16204575|CGD_REF: CAL0114768 homozygous diploid, classical genetics null Not recorded freeze-thaw resistance: decreased C. albicans orf19.2849 ORF AQY1 CAL0005142 PMID: 16204575|CGD_REF: CAL0114768 heterozygous diploid, classical genetics repressible Not recorded freeze-thaw resistance: decreased C. albicans orf19.2849 ORF AQY1 CAL0005142 PMID: 11746601|CGD_REF: CAL0080765 homozygous diploid, classical genetics null CAI-4 hyphal growth: normal solid Spider medium C. albicans orf19.2849 ORF AQY1 CAL0005142 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.2849 ORF AQY1 CAL0005142 PMID: 11746601|CGD_REF: CAL0080765 homozygous diploid, classical genetics null CAI-4 viable C. albicans orf19.2849 ORF AQY1 CAL0005142 PMID: 19187560|CGD_REF: CAL0122338 homozygous diploid, classical genetics null SC5314 biofilm formation: abnormal forms biofilm with altered detachment properties C. albicans orf19.2849 ORF AQY1 CAL0005142 PMID: 11746601|CGD_REF: CAL0080765 homozygous diploid, classical genetics null CAI-4 invasive growth: normal solid YPD medium C. albicans orf19.2849 ORF AQY1 CAL0005142 PMID: 11746601|CGD_REF: CAL0080765 homozygous diploid, classical genetics null CAI-4 osmotic stress resistance: increased greater-than-wild type resistance to both hyper- and hypoosmotic shock C. albicans orf19.2849 ORF AQY1 CAL0005142 PMID: 11746601|CGD_REF: CAL0080765 homozygous diploid, classical genetics null CAI-4 virulence: normal organ colonization is also normal mouse intravenous infection C. albicans orf19.2849 ORF AQY1 CAL0005142 PMID: 23563485|CGD_REF: CAL0000158903 homozygous diploid, classical genetics null a/alpha aqy1::FRT/aqy1::FRT SC5314 biofilm formation: abnormal RPMI medium 29 degrees C with rocking for 48 hr mutants have reduced vertical orientation of hyphae, an abnormal extracellular matrix, complete penetrabity to Sypro Ruby and human PMNs and increased sensitivity to fluconazole C. albicans orf19.2849 ORF AQY1 CAL0005142 PMID: 23563485|CGD_REF: CAL0000158903 heterozygous diploid, classical genetics repressible ADH1/adh1::pTET-AQY1-GFP::SATR (tet repressed) P37005 biofilm formation: abnormal RPMI medium 29 degrees C with rocking for 48 hr decreased Sypro Ruby and human PMN penetrability, decreased resistance to fluconazole C. albicans orf19.2849 ORF AQY1 CAL0005142 PMID: 23563485|CGD_REF: CAL0000158903 heterozygous diploid, classical genetics repressible aqy1::FRT/aqy1::FRT ADH1/adh1::pTET-AQY1-GFP::SATR SC5314 biofilm formation: abnormal RPMI medium 29 degrees C with rocking for 48 hr mutant has minor defects in vertical orientation of hyphae and reduced extracellular matrix, complete permeability to Sypro Ruby and human PMNs and decreased fluconazole resistance C. albicans orf19.2850 ORF CAL0005150 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.2850 ORF CAL0005150 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.2850 ORF CAL0005150 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.2850 ORF CAL0005150 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.2851 ORF CAL0005152 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.2852 ORF CAL0005153 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.2857 ORF CAL0005155 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.2859 ORF SRP40 CAL0005156 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.286 ORF CAL0004090 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient SC medium C. albicans orf19.2862 ORF RIB1 CAL0005171 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.2862 ORF RIB1 CAL0005171 PMID: 21135205|CGD_REF: CAL0139967 heterozygous diploid, competitive growth (large-scale identification of genes essential for virulence in mouse) repressible CAI-4 virulence: decreased mouse intravenous infection C. albicans orf19.2863.1 ORF ERV1 CAF0006965 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.2868 ORF CAL0005177 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.2868 ORF CAL0005177 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.2868 ORF CAL0005177 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.2868 ORF CAL0005177 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.287 ORF CAL0004094 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.287 ORF CAL0004094 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: decreased rate liquid synthetic complete medium C. albicans orf19.287 ORF CAL0004094 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.287 ORF CAL0004094 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.2873 ORF TOP2 CAL0005199 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.2873 ORF TOP2 CAL0005199 PMID: 22203422|CGD_REF: CAL0000143759 homozygous diploid, classical genetics null top2/top2Δ::hisG CAI-4 virulence: increased mouse intravenous infection C. albicans orf19.2873 ORF TOP2 CAL0005199 PMID: 22203422|CGD_REF: CAL0000143759 homozygous diploid, classical genetics null top2/top2Δ::hisG CAI-4 hyphal growth: increased C. albicans orf19.2873 ORF TOP2 CAL0005199 PMID: 20223895|CGD_REF: CAL0125138 homozygous diploid, classical genetics null top2::hisG-URA3-hisG/top2::hisG CAI-4 viable C. albicans orf19.2873 ORF TOP2 CAL0005199 PMID: 20223895|CGD_REF: CAL0125138 homozygous diploid, classical genetics null top2::hisG-URA3-hisG/top2::hisG CAI-4 resistance to chemicals: increased ketoconazole C. albicans orf19.2873 ORF TOP2 CAL0005199 PMID: 20223895|CGD_REF: CAL0125138 homozygous diploid, classical genetics null top2::hisG-URA3-hisG/top2::hisG CAI-4 resistance to chemicals: increased voriconazole C. albicans orf19.2873 ORF TOP2 CAL0005199 PMID: 20223895|CGD_REF: CAL0125138 homozygous diploid, classical genetics null top2::hisG-URA3-hisG/top2::hisG CAI-4 resistance to chemicals: increased miconazole C. albicans orf19.2873 ORF TOP2 CAL0005199 PMID: 20223895|CGD_REF: CAL0125138 homozygous diploid, classical genetics null top2::hisG-URA3-hisG/top2::hisG CAI-4 resistance to chemicals: increased itraconazole C. albicans orf19.2873 ORF TOP2 CAL0005199 PMID: 20223895|CGD_REF: CAL0125138 homozygous diploid, classical genetics null top2::hisG-URA3-hisG/top2::hisG CAI-4 resistance to chemicals: increased amphotericin B C. albicans orf19.2873 ORF TOP2 CAL0005199 PMID: 20223895|CGD_REF: CAL0125138 homozygous diploid, classical genetics null top2::hisG-URA3-hisG/top2::hisG CAI-4 resistance to chemicals: increased caspofungin C. albicans orf19.2873 ORF TOP2 CAL0005199 PMID: 20223895|CGD_REF: CAL0125138 homozygous diploid, classical genetics null top2::hisG-URA3-hisG/top2::hisG CAI-4 resistance to chemicals: increased terbinafine C. albicans orf19.2873 ORF TOP2 CAL0005199 PMID: 20223895|CGD_REF: CAL0125138 aneuploid, classical genetics overexpression MET3p::TOP2 CAI-4 resistance to chemicals: decreased ketoconazole C. albicans orf19.2873 ORF TOP2 CAL0005199 PMID: 20223895|CGD_REF: CAL0125138 aneuploid, classical genetics overexpression MET3p::TOP2 CAI-4 resistance to chemicals: decreased voriconazole C. albicans orf19.2873 ORF TOP2 CAL0005199 PMID: 20223895|CGD_REF: CAL0125138 aneuploid, classical genetics overexpression MET3p::TOP2 CAI-4 resistance to chemicals: decreased miconazole C. albicans orf19.2873 ORF TOP2 CAL0005199 PMID: 20223895|CGD_REF: CAL0125138 aneuploid, classical genetics overexpression MET3p::TOP2 CAI-4 resistance to chemicals: decreased itraconazole C. albicans orf19.2873 ORF TOP2 CAL0005199 PMID: 20223895|CGD_REF: CAL0125138 aneuploid, classical genetics overexpression MET3p::TOP2 CAI-4 resistance to chemicals: decreased amphotericin B C. albicans orf19.2873 ORF TOP2 CAL0005199 PMID: 20223895|CGD_REF: CAL0125138 aneuploid, classical genetics overexpression MET3p::TOP2 CAI-4 resistance to chemicals: decreased caspofungin C. albicans orf19.2873 ORF TOP2 CAL0005199 PMID: 20223895|CGD_REF: CAL0125138 aneuploid, classical genetics overexpression MET3p::TOP2 CAI-4 resistance to chemicals: decreased terbinafine C. albicans orf19.2875 ORF CAL0005200 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.2876 ORF CBF1 CAL0005201 PMID: 14659878|CGD_REF: CAL0080823 homozygous diploid, classical genetics null Not recorded heat sensitivity: increased C. albicans orf19.2876 ORF CBF1 CAL0005201 PMID: 14659878|CGD_REF: CAL0080823 homozygous diploid, classical genetics null Not recorded vegetative growth: decreased rate C. albicans orf19.2876 ORF CBF1 CAL0005201 PMID: 14659878|CGD_REF: CAL0080823 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.2876 ORF CBF1 CAL0005201 PMID: 14659878|CGD_REF: CAL0080823 homozygous diploid, classical genetics null Not recorded auxotrophy cysteine C. albicans orf19.2876 ORF CBF1 CAL0005201 PMID: 14659878|CGD_REF: CAL0080823 homozygous diploid, classical genetics null Not recorded cell size: increased cells are round and enlarged, and tend to aggregate C. albicans orf19.2876 ORF CBF1 CAL0005201 PMID: 14659878|CGD_REF: CAL0080823 homozygous diploid, classical genetics null Not recorded auxotrophy methionine C. albicans orf19.2877 ORF PDC11 CAL0005202 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.2877 ORF PDC11 CAL0005202 PMID: 21135205|CGD_REF: CAL0139967 heterozygous diploid, competitive growth (large-scale identification of genes essential for virulence in mouse) repressible CAI-4 virulence: normal mouse intravenous infection C. albicans orf19.288 ORF MET13 CAL0004097 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.2881 ORF MNN4 CAL0005219 PMID: 15271989|CGD_REF: CAL0082069 heterozygous diploid, classical genetics null CAI-4 hyphal growth: normal serum-containing or Spider media C. albicans orf19.2881 ORF MNN4 CAL0005219 PMID: 15271989|CGD_REF: CAL0082069 homozygous diploid, classical genetics null CAI-4 hyphal growth: normal serum-containing or Spider media C. albicans orf19.2881 ORF MNN4 CAL0005219 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.2881 ORF MNN4 CAL0005219 PMID: 15271989|CGD_REF: CAL0082069 heterozygous diploid, classical genetics null Not recorded viable C. albicans orf19.2881 ORF MNN4 CAL0005219 PMID: 15271989|CGD_REF: CAL0082069 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.2881 ORF MNN4 CAL0005219 PMID: 15821124|CGD_REF: CAL0104047 heterozygous diploid, classical genetics null Not recorded viable C. albicans orf19.2881 ORF MNN4 CAL0005219 PMID: 15821124|CGD_REF: CAL0104047 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.2881 ORF MNN4 CAL0005219 PMID: 15271989|CGD_REF: CAL0082069 heterozygous diploid, classical genetics null Not recorded adhesion: normal adhesion to host macrophages C. albicans orf19.2881 ORF MNN4 CAL0005219 PMID: 15271989|CGD_REF: CAL0082069 homozygous diploid, classical genetics null Not recorded adhesion: normal adhesion to host macrophages C. albicans orf19.2881 ORF MNN4 CAL0005219 PMID: 15271989|CGD_REF: CAL0082069 heterozygous diploid, classical genetics null Not recorded cell wall morphology: abnormal altered cell wall mannans, as detected by Alcian Blue binding intermediate between that of the homozygous null mutant and wild type C. albicans orf19.2881 ORF MNN4 CAL0005219 PMID: 15821124|CGD_REF: CAL0104047 heterozygous diploid, classical genetics null Not recorded cell wall morphology: abnormal altered cell wall mannans, as detected by decreased Alcian Blue binding C. albicans orf19.2881 ORF MNN4 CAL0005219 PMID: 15821124|CGD_REF: CAL0104047 homozygous diploid, classical genetics null Not recorded cell wall morphology: abnormal altered cell wall mannans, as detected by decreased Alcian Blue binding C. albicans orf19.2881 ORF MNN4 CAL0005219 PMID: 15271989|CGD_REF: CAL0082069 homozygous diploid, classical genetics null Not recorded cell wall morphology: abnormal altered cell wall mannans, as detected by lack of Alcian Blue binding C. albicans orf19.2881 ORF MNN4 CAL0005219 PMID: 15821124|CGD_REF: CAL0104047 homozygous diploid, classical genetics null Not recorded cell wall morphology: abnormal increased cell surface hydrophobicity C. albicans orf19.2881 ORF MNN4 CAL0005219 PMID: 20123707|CGD_REF: CAL0125018 homozygous diploid, classical genetics null CAI-4 resistance to phagocytosis: increased reduced rate of uptake by macrophages in vitro model of infection (J774.1 cells and murine bone-marrow-derived macrophages) C. albicans orf19.2881 ORF MNN4 CAL0005219 PMID: 15271989|CGD_REF: CAL0082069 homozygous diploid, classical genetics null Not recorded virulence: normal wild-type kidney colonization mouse intravenous infection C. albicans orf19.2881 ORF MNN4 CAL0005219 PMID: 15271989|CGD_REF: CAL0082069 heterozygous diploid, classical genetics null Not recorded virulence: normal wild-type kidney colonization and macrophage engulfment mouse intravenous infection C. albicans orf19.2881 ORF MNN4 CAL0005219 PMID: 15821124|CGD_REF: CAL0104047 homozygous diploid, classical genetics null Not recorded virulence: normal mouse intravenous infection C. albicans orf19.2882 ORF XUT1 CAL0005220 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.2884 ORF CDC68 CAL0005222 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.2884 ORF CDC68 CAL0005222 PMID: 12420162|CGD_REF: CAL0080882 heterozygous diploid, classical genetics null Not recorded viable C. albicans orf19.2884 ORF CDC68 CAL0005222 PMID: 12420162|CGD_REF: CAL0080882 homozygous diploid, classical genetics null Not recorded inviable homozygous null mutant strain could not be recovered, suggesting that the gene is essential under the selection conditions C. albicans orf19.2885 ORF PRI2 CAL0005223 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.2886 ORF CEK1 CAL0005224 PMID: 19563901|CGD_REF: CAL0123856 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased Calcofluor White C. albicans orf19.2886 ORF CEK1 CAL0005224 PMID: 19563901|CGD_REF: CAL0123856 homozygous diploid, classical genetics null Not recorded flocculation: increased C. albicans orf19.2886 ORF CEK1 CAL0005224 PMID: 9596738|CGD_REF: CAL0080971 homozygous diploid, classical genetics null CAI-4 hyphal growth: abnormal solid SLAD medium decreased and aberrant hyphal growth C. albicans orf19.2886 ORF CEK1 CAL0005224 PMID: 9596738|CGD_REF: CAL0080971 homozygous diploid, classical genetics null CAI-4 hyphal growth: normal liquid media C. albicans orf19.2886 ORF CEK1 CAL0005224 PMID: 9596738|CGD_REF: CAL0080971 homozygous diploid, classical genetics null CAI-4 hyphal growth: normal solid Lee's plus glucose or solid Spider plus glucose media C. albicans orf19.2886 ORF CEK1 CAL0005224 PMID: 9596738|CGD_REF: CAL0080971 homozygous diploid, classical genetics null CAI-4 hyphal growth: absent solid Lee's plus mannitol or Spider plus mannitol media C. albicans orf19.2886 ORF CEK1 CAL0005224 PMID: 9596738|CGD_REF: CAL0080971 heterozygous diploid, classical genetics null CAI-4 hyphal growth: decreased solid Lee's plus mannitol or Spider plus mannitol media C. albicans orf19.2886 ORF CEK1 CAL0005224 PMID: 9596738|CGD_REF: CAL0080971 homozygous diploid, classical genetics null CAI-4 hyphal growth: decreased rate solid serum-containing medium C. albicans orf19.2886 ORF CEK1 CAL0005224 PMID: 9596738|CGD_REF: CAL0080971 homozygous diploid, classical genetics null Not recorded vegetative growth: normal rate liquid YPD C. albicans orf19.2886 ORF CEK1 CAL0005224 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.2886 ORF CEK1 CAL0005224 PMID: 12453219|CGD_REF: CAL0080981 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.2886 ORF CEK1 CAL0005224 PMID: 9596738|CGD_REF: CAL0080971 heterozygous diploid, classical genetics null Not recorded viable C. albicans orf19.2886 ORF CEK1 CAL0005224 PMID: 9596738|CGD_REF: CAL0080971 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.2886 ORF CEK1 CAL0005224 PMID: 20100861|CGD_REF: CAL0124920 homozygous diploid, classical genetics null cell wall morphology: abnormal less electron-dense cell-walls seen in transmission electron microscopy C. albicans orf19.2886 ORF CEK1 CAL0005224 PMID: 20100861|CGD_REF: CAL0124920 homozygous diploid, classical genetics null chemical compound accumulation: increased beta-D-glucan increased beta-glucan exposure on the cell wall surface C. albicans orf19.2886 ORF CEK1 CAL0005224 PMID: 18162580|CGD_REF: CAL0118948 homozygous diploid, classical genetics null Not recorded mating response: abnormal reduced and delayed shmoo formation in opaque cells in response to alpha pheromone C. albicans orf19.2886 ORF CEK1 CAL0005224 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, competitive growth (haploinsufficient phenotype assay, barcode deletion set) null SC5314 resistance to chemicals: decreased amphotericin B C. albicans orf19.2886 ORF CEK1 CAL0005224 PMID: 18162580|CGD_REF: CAL0118948 homozygous diploid, classical genetics null Not recorded phenotypic switching: normal C. albicans orf19.2886 ORF CEK1 CAL0005224 PMID: 18162580|CGD_REF: CAL0118948 homozygous diploid, classical genetics null Not recorded pheromone sensitivity: decreased alpha factor reduced aggregation of white-phase cells C. albicans orf19.2886 ORF CEK1 CAL0005224 PMID: 19542310|CGD_REF: CAL0123805 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased caspofungin C. albicans orf19.2886 ORF CEK1 CAL0005224 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, competitive growth (haploinsufficient phenotype assay, barcode deletion set) null SC5314 resistance to chemicals: decreased ergosterol analogs (ECC69 and/or ECC1384) C. albicans orf19.2886 ORF CEK1 CAL0005224 PMID: 19563901|CGD_REF: CAL0123856 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased Congo Red C. albicans orf19.2886 ORF CEK1 CAL0005224 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.2886 ORF CEK1 CAL0005224 PMID: 20100861|CGD_REF: CAL0124920 homozygous diploid, classical genetics null Other C. albicans resistance to killing by host cells: decreased in vitro model of infection (human monocyte-derived dendritic cells (hDCs) and macrophages) C. albicans orf19.2886 ORF CEK1 CAL0005224 PMID: 17346314|CGD_REF: CAL0118020 homozygous diploid, classical genetics null CAI-4 resistance to killing by host cells: increased 2 hrs at MOI 1:40 in vitro model of infection (human PMN) C. albicans orf19.2886 ORF CEK1 CAL0005224 PMID: 20100861|CGD_REF: CAL0124920 homozygous diploid, classical genetics null Other C. albicans resistance to phagocytosis: decreased cek1/cek1 mutants are phagocytosed about twice as readily as wild-type in vitro model of infection (human monocyte-derived dendritic cells or RAW 264.7 macrophages) C. albicans orf19.2886 ORF CEK1 CAL0005224 PMID: 20100861|CGD_REF: CAL0124920 homozygous diploid, classical genetics null Other C. albicans resistance to phagocytosis: decreased in vitro model of infection (human monocyte-derived dendritic cells and macrophages) C. albicans orf19.2886 ORF CEK1 CAL0005224 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: abnormal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.2886 ORF CEK1 CAL0005224 PMID: 18162580|CGD_REF: CAL0118948 homozygous diploid, classical genetics null P37005 biofilm formation: decreased white cells form a biofilm of reduced thickness in the presence of opaque cells of the opposite mating type C. albicans orf19.2886 ORF CEK1 CAL0005224 PMID: 12381467|CGD_REF: CAL0087147 homozygous diploid, classical genetics null Not recorded virulence: decreased Galleria mellonella (Greater Wax Moth) larvae insect infection C. albicans orf19.2886 ORF CEK1 CAL0005224 PMID: 9596738|CGD_REF: CAL0080971 homozygous diploid, classical genetics null Not recorded virulence: decreased mouse intravenous infection C. albicans orf19.2886 ORF CEK1 CAL0005224 PMID: 9741091|CGD_REF: CAL0080972 heterozygous diploid, classical genetics null Not recorded virulence: normal reintegrant mouse mammary gland infection C. albicans orf19.2886 ORF CEK1 CAL0005224 PMID: 9741091|CGD_REF: CAL0080972 homozygous diploid, classical genetics null Not recorded virulence: decreased mouse mammary gland infection C. albicans orf19.2886 ORF CEK1 CAL0005224 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.2886 ORF CEK1 CAL0005224 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.2893 ORF CAL0005248 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.2895 ORF VMA8 CAL0005252 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.2896 ORF SOU1 CAL0005253 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.2896 ORF SOU1 CAL0005253 PMID: 12940995|CGD_REF: CAL0081934 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.2896 ORF SOU1 CAL0005253 PMID: 9560244|CGD_REF: CAL0081933 homozygous diploid, classical genetics null Not recorded utilization of carbon source: absent L-sorbose C. albicans orf19.2897 ORF SOU2 CAL0005254 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.2898 ORF CAL0005255 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.29 ORF CAL0000527 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.290 ORF KRE5 CAL0004102 PMID: 15590817|CGD_REF: CAL0082483 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased Calcofluor White C. albicans orf19.290 ORF KRE5 CAL0004102 PMID: 15590817|CGD_REF: CAL0082483 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased sodium dodecyl sulfate C. albicans orf19.290 ORF KRE5 CAL0004102 PMID: 15590817|CGD_REF: CAL0082483 homozygous diploid, classical genetics null CAI-4 hyphal growth: decreased solid Spider, Lee's plus mannitol, or serum-containing media; liquid Lee's or serum-containing media C. albicans orf19.290 ORF KRE5 CAL0004102 PMID: 15590817|CGD_REF: CAL0082483 homozygous diploid, classical genetics null Not recorded vegetative growth: decreased rate C. albicans orf19.290 ORF KRE5 CAL0004102 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.290 ORF KRE5 CAL0004102 PMID: 15590817|CGD_REF: CAL0082483 heterozygous diploid, classical genetics null Not recorded viable C. albicans orf19.290 ORF KRE5 CAL0004102 PMID: 15590817|CGD_REF: CAL0082483 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.290 ORF KRE5 CAL0004102 PMID: 15590817|CGD_REF: CAL0082483 homozygous diploid, classical genetics null Not recorded adhesion: decreased adhesion to human epithelial (HeLa) cells C. albicans orf19.290 ORF KRE5 CAL0004102 PMID: 15590817|CGD_REF: CAL0082483 homozygous diploid, classical genetics null Not recorded cell size: increased cells are enlarged, have large vacuoles, and exhibit clumping; defects are partially rescued by N-acetylglucosamine C. albicans orf19.290 ORF KRE5 CAL0004102 PMID: 16652171|CGD_REF: CAL0115929 homozygous diploid, classical genetics null Not recorded cell wall morphology: abnormal beta-glucan is unmasked C. albicans orf19.290 ORF KRE5 CAL0004102 PMID: 15590817|CGD_REF: CAL0082483 homozygous diploid, classical genetics null Not recorded chemical compound accumulation: decreased (1->6)-beta-D-glucan decreased cell wall beta-1,6-glucan C. albicans orf19.290 ORF KRE5 CAL0004102 PMID: 15590817|CGD_REF: CAL0082483 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased caffeine C. albicans orf19.290 ORF KRE5 CAL0004102 PMID: 15590817|CGD_REF: CAL0082483 heterozygous diploid, classical genetics null Not recorded resistance to chemicals: increased Hygromycin B C. albicans orf19.290 ORF KRE5 CAL0004102 PMID: 16652171|CGD_REF: CAL0115929 homozygous diploid, classical genetics null SC5314 induction of host response: abnormal mutant elicits enhanced TNFalpha response in vitro model of infection (RAW264.7 or mouse bone marrow derived macrophages) C. albicans orf19.290 ORF KRE5 CAL0004102 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: increased growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.290 ORF KRE5 CAL0004102 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: abnormal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.290 ORF KRE5 CAL0004102 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, classical genetics null SN152 germ tube formation: decreased serum-containing medium C. albicans orf19.290 ORF KRE5 CAL0004102 PMID: 15590817|CGD_REF: CAL0082483 homozygous diploid, classical genetics null Not recorded virulence: absent mouse intravenous infection C. albicans orf19.290 ORF KRE5 CAL0004102 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: decreased rate liquid synthetic complete medium C. albicans orf19.290 ORF KRE5 CAL0004102 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.2901 ORF NUP60 CAL0005940 PMID: 14663094|CGD_REF: CAL0080633 homozygous diploid, systematic mutation set (homozygous insertion mutants generated with URA3-ARG4-URA3 (UAU1) cassette) null BWP17 viable C. albicans orf19.2903 ORF AGO1 CAL0005941 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.2903 ORF AGO1 CAL0005941 PMID: 22173636|CGD_REF: CAL0000143754 homozygous diploid, classical genetics null BWP17 viable C. albicans orf19.2907 ORF PGA42 CAL0005947 PMID: 18765290|CGD_REF: CAL0119430 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.2908 ORF CAL0005949 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.2909 ORF ERG26 CAL0005951 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.2909 ORF ERG26 CAL0005951 PMID: 12702354|CGD_REF: CAL0081258 homozygous diploid, classical genetics null Not recorded inviable homozygous null mutant strain could not be recovered, suggesting that the gene is essential under the selection conditions C. albicans orf19.2909 ORF ERG26 CAL0005951 PMID: 15893902|CGD_REF: CAL0114689 heterozygous diploid, classical genetics repressible Not recorded inviable not rescued by various exogenous sources of sterol, indicating lack of uptake C. albicans orf19.2909 ORF ERG26 CAL0005951 PMID: 12702354|CGD_REF: CAL0081258 heterozygous diploid, classical genetics repressible Not recorded inviable C. albicans orf19.2909 ORF ERG26 CAL0005951 PMID: 21135205|CGD_REF: CAL0139967 heterozygous diploid, competitive growth (large-scale identification of genes essential for virulence in mouse) repressible CAI-4 virulence: normal mouse intravenous infection C. albicans orf19.2910 ORF PGA43 CAL0005964 PMID: 18765290|CGD_REF: CAL0119430 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.2911 ORF SEC3 CAL0005966 PMID: 17504812|CGD_REF: CAL0117850 homozygous diploid, classical genetics null Not recorded heat sensitivity: increased 37 deg C slow growth at 37 deg C; no growth at 42 deg C C. albicans orf19.2911 ORF SEC3 CAL0005966 PMID: 17504812|CGD_REF: CAL0117850 homozygous diploid, classical genetics null BWP17 hyphal growth: absent unable to continue hyphal growth after germ tube formation C. albicans orf19.2911 ORF SEC3 CAL0005966 PMID: 17504812|CGD_REF: CAL0117850 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.2911 ORF SEC3 CAL0005966 PMID: 17504812|CGD_REF: CAL0117850 homozygous diploid, classical genetics null Not recorded protein/peptide distribution: abnormal normal polarized distribution of cell polarity regulators Cdc42p, Spa2, Bni1p is not observed Cdc42p C. albicans orf19.2915 ORF CAL0005969 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.2916 ORF CAL0005971 PMID: 20494978|CGD_REF: CAL0125636 heterozygous diploid, classical genetics null BWP17 resistance to chemicals: decreased clotrimazole (75 uM) growth in liquid culture confirmation of mutant phenotypes for heterozygous transposon insertion strains showing sensitivity in a large-scale assay C. albicans orf19.2917 ORF CAL0005973 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.2917 ORF CAL0005973 PMID: 19623926|CGD_REF: CAL0124054 heterozygous diploid, competitive growth (haploinsufficient phenotype assay, barcode deletion set) null SC5314 resistance to chemicals: increased parnafungin C. albicans orf19.2917 ORF CAL0005973 PMID: 21135205|CGD_REF: CAL0139967 heterozygous diploid, large-scale survey (large-scale identification of genes essential for virulence in mouse) repressible CAI-4 virulence: absent mouse intravenous infection C. albicans orf19.292 ORF CAL0004106 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 invasive growth: decreased solid SLAD media C. albicans orf19.2920 ORF CAL0005985 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.2921 ORF CAL0005987 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.2922 ORF CAL0005988 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.2923 ORF CAL0005989 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.2925 ORF CAL0005991 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.2926 ORF CAL0005993 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.2929 ORF GSC1 CAL0005999 PMID: 9209021|CGD_REF: CAL0081298 heterozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased Calcofluor White C. albicans orf19.2929 ORF GSC1 CAL0005999 PMID: 18180350|CGD_REF: CAL0118817 homozygous diploid, classical genetics unspecified Other C. albicans hyphal growth: increased liquid GlcNAc- or serum-containing media increased length and abundance of hyphae; homozygous S645Y mutant C. albicans orf19.2929 ORF GSC1 CAL0005999 PMID: 19154328|CGD_REF: CAL0122236 homozygous diploid, classical genetics null Other C. albicans hyphal growth: normal semisolid substrate wild-type hyphal tip oscillation C. albicans orf19.2929 ORF GSC1 CAL0005999 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.2929 ORF GSC1 CAL0005999 PMID: 9209021|CGD_REF: CAL0081298 heterozygous diploid, classical genetics null Not recorded viable wild-type growth rate C. albicans orf19.2929 ORF GSC1 CAL0005999 PMID: 18180350|CGD_REF: CAL0118817 homozygous diploid, classical genetics unspecified gsc1-S645Y Not recorded adhesion: increased adhesion to plastic C. albicans orf19.2929 ORF GSC1 CAL0005999 PMID: 18180350|CGD_REF: CAL0118817 homozygous diploid, classical genetics unspecified gsc1-S645Y Not recorded cell wall morphology: abnormal C. albicans orf19.2929 ORF GSC1 CAL0005999 PMID: 18180350|CGD_REF: CAL0118817 homozygous diploid, classical genetics unspecified gsc1-S645Y Not recorded resistance to chemicals: increased micafungin C. albicans orf19.2929 ORF GSC1 CAL0005999 PMID: 18180350|CGD_REF: CAL0118817 homozygous diploid, classical genetics unspecified gsc1-S645Y Not recorded viable homozygous S645Y mutant, also called CO23RFK, a micafungin-selected variant of patient isolate CO23S C. albicans orf19.2929 ORF GSC1 CAL0005999 PMID: 18180350|CGD_REF: CAL0118817 homozygous diploid, classical genetics unspecified gsc1-S645Y Not recorded virulence: increased mouse intravenous infection C. albicans orf19.2929 ORF GSC1 CAL0005999 PMID: 18180350|CGD_REF: CAL0118817 homozygous diploid, classical genetics unspecified gsc1-S645Y Not recorded virulence: normal rat vaginal infection C. albicans orf19.2929 ORF GSC1 CAL0005999 PMID: 18180350|CGD_REF: CAL0118817 homozygous diploid, classical genetics unspecified gsc1-S645Y Other C. albicans biofilm formation: increased increased biofilm formation; homozygous S645Y mutant C. albicans orf19.2929 ORF GSC1 CAL0005999 PMID: 18180350|CGD_REF: CAL0118817 homozygous diploid, classical genetics unspecified Other C. albicans invasive growth: increased solid serum-containing medium homozygous S645Y mutant C. albicans orf19.2929 ORF GSC1 CAL0005999 PMID: 14507372|CGD_REF: CAL0088818 heterozygous diploid, large-scale survey (large-scale identification of essential genes by gene replacement and conditional expression (GRACE) method) repressible CAI-4 inviable one allele is deleted and the other is placed under repressible Tet promoter C. albicans orf19.2929 ORF GSC1 CAL0005999 PMID: 9209021|CGD_REF: CAL0081298 homozygous diploid, classical genetics null Not recorded inviable homozygous null mutant strain could not be recovered, suggesting that the gene is essential under the selection conditions C. albicans orf19.2929 ORF GSC1 CAL0005999 PMID: 9371352|CGD_REF: CAL0081299 homozygous diploid, classical genetics null Not recorded inviable homozygous null mutant strain could not be recovered, suggesting that the gene is essential under the selection conditions C. albicans orf19.2929 ORF GSC1 CAL0005999 PMID: 9209021|CGD_REF: CAL0081298 heterozygous diploid, classical genetics null Not recorded cellular morphology: normal C. albicans orf19.2929 ORF GSC1 CAL0005999 PMID: 8757860|CGD_REF: CAL0081295 heterozygous diploid, classical genetics unspecified Not recorded resistance to chemicals: increased aculeacin A CAI4R1 is heterozygous for an unspecified mutant allele C. albicans orf19.2929 ORF GSC1 CAL0005999 PMID: 9209021|CGD_REF: CAL0081298 heterozygous diploid, classical genetics null Not recorded chemical compound accumulation: decreased (1->6)-beta-D-glucan decreased cell wall beta-1,6-glucan C. albicans orf19.2929 ORF GSC1 CAL0005999 PMID: 8757860|CGD_REF: CAL0081295 heterozygous diploid, classical genetics unspecified Not recorded resistance to chemicals: increased Echinocandin B CAI4R1 is heterozygous for an unspecified mutant allele C. albicans orf19.2929 ORF GSC1 CAL0005999 PMID: 18955538|CGD_REF: CAL0120461 homozygous diploid, classical genetics unspecified Not recorded resistance to chemicals: increased Echinocandin B multiple mutations examined, those affecting Ser645 cause greatest effect C. albicans orf19.2929 ORF GSC1 CAL0005999 PMID: 9209021|CGD_REF: CAL0081298 heterozygous diploid, classical genetics null Not recorded resistance to chemicals: normal Echinocandin B C. albicans orf19.2929 ORF GSC1 CAL0005999 PMID: 8757860|CGD_REF: CAL0081295 heterozygous diploid, classical genetics unspecified Not recorded resistance to chemicals: increased dihydropapulacandin CAI4R1 is heterozygous for an unspecified mutant allele C. albicans orf19.2929 ORF GSC1 CAL0005999 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, competitive growth (haploinsufficient phenotype assay, barcode deletion set) null SC5314 resistance to chemicals: decreased ergokonin A C. albicans orf19.2929 ORF GSC1 CAL0005999 PMID: 15793151|CGD_REF: CAL0104093 unknown ploidy, classical genetics unspecified Other C. albicans resistance to chemicals: decreased amphotericin B C. albicans orf19.2929 ORF GSC1 CAL0005999 PMID: 15793151|CGD_REF: CAL0104093 unknown ploidy, classical genetics unspecified Other C. albicans resistance to chemicals: decreased fluconazole C. albicans orf19.2929 ORF GSC1 CAL0005999 PMID: 15793151|CGD_REF: CAL0104093 unknown ploidy, classical genetics unspecified Other C. albicans resistance to chemicals: decreased flucytosine C. albicans orf19.2929 ORF GSC1 CAL0005999 PMID: 15793151|CGD_REF: CAL0104093 unknown ploidy, classical genetics unspecified Other C. albicans resistance to chemicals: decreased itraconazole C. albicans orf19.2929 ORF GSC1 CAL0005999 PMID: 16048935|CGD_REF: CAL0114429 unknown ploidy, classical genetics unspecified gsc1-S645P Other C. albicans resistance to chemicals: increased caspofungin|echinocandin B C. albicans orf19.2929 ORF GSC1 CAL0005999 PMID: 16048935|CGD_REF: CAL0114429 unknown ploidy, classical genetics unspecified gsc1-S645PY Other C. albicans resistance to chemicals: increased caspofungin|echinocandin B C. albicans orf19.2929 ORF GSC1 CAL0005999 PMID: 8757860|CGD_REF: CAL0081295 unknown ploidy, classical genetics unspecified CAI-4 virulence: normal mouse intravenous infection C. albicans orf19.2929 ORF GSC1 CAL0005999 PMID: 16870797|CGD_REF: CAL0116364 unknown ploidy, classical genetics unspecified gsc1-F641Y Other C. albicans resistance to chemicals: increased Echinocandin B C. albicans orf19.2929 ORF GSC1 CAL0005999 PMID: 8757860|CGD_REF: CAL0081295 heterozygous diploid, classical genetics unspecified CAI-4 resistance to chemicals: increased pneumocandin L-733560 CAI4R1 is heterozygous for an unspecified mutant allele mouse intravenous infection C. albicans orf19.2929 ORF GSC1 CAL0005999 PMID: 16048935|CGD_REF: CAL0114429 unknown ploidy, classical genetics unspecified gsc1-S645F Other C. albicans resistance to chemicals: increased Echinocandin B|caspofungin C. albicans orf19.2929 ORF GSC1 CAL0005999 PMID: 16048935|CGD_REF: CAL0114429 unknown ploidy, classical genetics unspecified gsc1-S645F Other C. albicans resistance to chemicals: increased Echinocandin B|caspofungin C. albicans orf19.2929 ORF GSC1 CAL0005999 PMID: 16716141|CGD_REF: CAL0116066 unknown ploidy, classical genetics unspecified gsc1-S645P Other C. albicans resistance to chemicals: increased caspofungin C. albicans orf19.2929 ORF GSC1 CAL0005999 PMID: 16716141|CGD_REF: CAL0116066 unknown ploidy, classical genetics unspecified gsc1-S645P Other C. albicans resistance to chemicals: increased caspofungin C. albicans orf19.2929 ORF GSC1 CAL0005999 PMID: 9371352|CGD_REF: CAL0081299 unknown ploidy, classical genetics unspecified CAI-4 resistance to chemicals: increased Echinocandin B C. albicans orf19.2929 ORF GSC1 CAL0005999 PMID: 15793151|CGD_REF: CAL0104093 unknown ploidy, classical genetics unspecified CAI-4 resistance to chemicals: increased caspofungin C. albicans orf19.2929 ORF GSC1 CAL0005999 PMID: 16723566|CGD_REF: CAL0116067 unknown ploidy, classical genetics unspecified Other C. albicans resistance to chemicals: increased caspofungin C. albicans orf19.2929 ORF GSC1 CAL0005999 PMID: 9371352|CGD_REF: CAL0081299 unknown ploidy, classical genetics unspecified CAI-4 resistance to chemicals: increased pneumocandin B0 C. albicans orf19.2929 ORF GSC1 CAL0005999 PMID: 8757860|CGD_REF: CAL0081295 unknown ploidy, classical genetics unspecified CAI-4 hyphal growth: normal RPMI 1640 medium at 37 deg C C. albicans orf19.2929 ORF GSC1 CAL0005999 PMID: 21666076|CGD_REF: CAL0000142107 heterozygous diploid, classical genetics null gsc1(fks1)::URA3 BWP17 viable C. albicans orf19.2929 ORF GSC1 CAL0005999 PMID: 21666076|CGD_REF: CAL0000142107 heterozygous diploid, classical genetics null gsc1::HisG-URA3-HisG/GSC1 CAI-4 viable C. albicans orf19.2929 ORF GSC1 CAL0005999 PMID: 21666076|CGD_REF: CAL0000142107 heterozygous diploid, classical genetics null gsc1::HisG-URA3-HisG/GSC1 CAI-4 resistance to chemicals fluconazole increased susceptibility to fluconazole in a biofilm C. albicans orf19.2929 ORF GSC1 CAL0005999 PMID: 20233776|CGD_REF: CAL0125113 homozygous diploid, classical genetics unspecified gsc1-S645F Other C. albicans resistance to chemicals: increased micafungin (4 mg/l) C. albicans orf19.2929 ORF GSC1 CAL0005999 PMID: 20233776|CGD_REF: CAL0125113 heterozygous diploid, classical genetics unspecified gsc1-S645F Other C. albicans resistance to chemicals: increased micafungin (1 mg/l) C. albicans orf19.2929 ORF GSC1 CAL0005999 PMID: 21135205|CGD_REF: CAL0139967 heterozygous diploid, large-scale survey (large-scale identification of genes essential for virulence in mouse) repressible CAI-4 virulence: absent mouse intravenous infection C. albicans orf19.2930 ORF CAL0006012 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.2933 ORF CAL0006014 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.2935 ORF RPL10 CAL0006017 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.2935 ORF RPL10 CAL0006017 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient YPD medium C. albicans orf19.2935 ORF RPL10 CAL0006017 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient SC medium C. albicans orf19.2935 ORF RPL10 CAL0006017 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient SLAD medium C. albicans orf19.2937 ORF PMM1 CAL0006021 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.2938 ORF CAL0006023 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.2938 ORF CAL0006023 PMID: 14663094|CGD_REF: CAL0080633 homozygous diploid, systematic mutation set (homozygous insertion mutants generated with URA3-ARG4-URA3 (UAU1) cassette) null BWP17 viable C. albicans orf19.2939 ORF CAL0006025 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.2940 ORF CAL0006034 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.2940 ORF CAL0006034 PMID: 21135205|CGD_REF: CAL0139967 heterozygous diploid, competitive growth (large-scale identification of genes essential for virulence in mouse) repressible CAI-4 virulence: decreased mouse intravenous infection C. albicans orf19.2941 ORF SCW4 CAL0006035 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.2941 ORF SCW4 CAL0006035 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.2941 ORF SCW4 CAL0006035 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.2941 ORF SCW4 CAL0006035 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.2941 ORF SCW4 CAL0006035 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.2942 ORF DIP5 CAL0006036 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.2942 ORF DIP5 CAL0006036 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, competitive growth (haploinsufficient phenotype assay, barcode deletion set) null SC5314 resistance to chemicals: decreased ergosterol analogs (ECC69 and/or ECC1384) C. albicans orf19.2945 ORF PUT4 CAL0006038 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.2945 ORF PUT4 CAL0006038 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient SLAD medium C. albicans orf19.2945 ORF PUT4 CAL0006038 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 invasive growth: decreased solid SLAD media C. albicans orf19.2946 ORF HNM4 CAL0006039 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.2947 ORF SNZ1 CAL0006040 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.2948 ORF SNO1 CAL0006041 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.2949 ORF IML1 CAL0006042 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.2951 ORF HOM6 CAL0006049 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.2951 ORF HOM6 CAL0006049 PMID: 21135205|CGD_REF: CAL0139967 heterozygous diploid, competitive growth (large-scale identification of genes essential for virulence in mouse) repressible CAI-4 virulence: decreased mouse intravenous infection C. albicans orf19.2952 ORF EXG2 CAL0006050 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.2952 ORF EXG2 CAL0006050 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.2952 ORF EXG2 CAL0006050 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.2952 ORF EXG2 CAL0006050 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.2952 ORF EXG2 CAL0006050 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.2952 ORF EXG2 CAL0006050 PMID: 21135205|CGD_REF: CAL0139967 heterozygous diploid, competitive growth (large-scale identification of genes essential for virulence in mouse) repressible CAI-4 virulence: normal mouse intravenous infection C. albicans orf19.2953 ORF TOM20 CAL0006051 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.2956 ORF MGM101 CAL0006053 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, competitive growth (haploinsufficient phenotype assay, barcode deletion set) null SC5314 resistance to chemicals: decreased tubercidin C. albicans orf19.2956 ORF MGM101 CAL0006053 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.2956 ORF MGM101 CAL0006053 PMID: 21135205|CGD_REF: CAL0139967 heterozygous diploid, competitive growth (large-scale identification of genes essential for virulence in mouse) repressible CAI-4 virulence: decreased mouse intravenous infection C. albicans orf19.2959.1 ORF CAF0006969 PMID: 22438810|CGD_REF: CAL0000156986 homozygous diploid, classical genetics null BWP17 viable C. albicans orf19.2959.1 ORF CAF0006969 PMID: 22438810|CGD_REF: CAL0000156986 homozygous diploid, classical genetics null BWP17 virulence: decreased mutants have reduced capacity to damage oral epithelial cells in vitro model of infection (monolayers of oral epithelial cells) C. albicans orf19.2960 ORF FRS2 CAL0006075 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.2961 ORF CAL0006077 PMID: 20041210|CGD_REF: CAL0124764 homozygous diploid, systematic mutation set null SN152 resistance to chemicals: decreased rapamycin strongly sensitive C. albicans orf19.2961 ORF CAL0006077 PMID: 15964282|CGD_REF: CAL0114274 homozygous diploid, systematic mutation set (split-marker transposon insertion strategy to disrupt both alleles) null BWP17 inviable homozygous null mutant strain could not be recovered, suggesting that the gene is essential under the selection conditions C. albicans orf19.2961 ORF CAL0006077 PMID: 20041210|CGD_REF: CAL0124764 homozygous diploid, systematic mutation set null SN152 metal resistance: increased copper(2+) strongly resistant C. albicans orf19.2961 ORF CAL0006077 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: decreased growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.2961 ORF CAL0006077 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.2961 ORF CAL0006077 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.2961 ORF CAL0006077 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.2963 ORF CAL0006079 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.2964 ORF CAL0006080 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.2964 ORF CAL0006080 PMID: 21135205|CGD_REF: CAL0139967 heterozygous diploid, large-scale survey (large-scale identification of genes essential for virulence in mouse) repressible CAI-4 virulence: absent mouse intravenous infection C. albicans orf19.2965 ORF CAL0006081 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.2966 ORF CAL0006082 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.2967 ORF TIF34 CAL0006083 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.2967 ORF TIF34 CAL0006083 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, competitive growth (haploinsufficient phenotype assay, barcode deletion set) null SC5314 resistance to chemicals: decreased verrucarin C. albicans orf19.2967 ORF TIF34 CAL0006083 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, competitive growth (haploinsufficient phenotype assay, barcode deletion set) null SC5314 resistance to chemicals: decreased roridin A C. albicans orf19.2967 ORF TIF34 CAL0006083 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient YPD medium C. albicans orf19.2967 ORF TIF34 CAL0006083 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient SC medium C. albicans orf19.2967 ORF TIF34 CAL0006083 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient SLAD medium C. albicans orf19.2970 ORF LYS2 CAL0006102 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.2970 ORF LYS2 CAL0006102 PMID: 10647122|CGD_REF: CAL0081494 homozygous diploid, classical genetics null lys2::hisG-URA3-hisG CAI-4 auxotrophy L-lysine C. albicans orf19.2970 ORF LYS2 CAL0006102 PMID: 10647122|CGD_REF: CAL0081494 homozygous diploid, classical genetics null lys2::hisG-URA3-hisG CAI-4 filamentous growth: normal solid Spider medium C. albicans orf19.2970 ORF LYS2 CAL0006102 PMID: 10647122|CGD_REF: CAL0081494 homozygous diploid, classical genetics null lys2::hisG-URA3-hisG CAI-4 hyphal growth: normal liquid Spider media C. albicans orf19.2970 ORF LYS2 CAL0006102 PMID: 10647122|CGD_REF: CAL0081494 heterozygous diploid, classical genetics null lys2::hisG-URA3-hisG CAI-4 viable both alleles contribute to cellular AAR activity C. albicans orf19.2970 ORF LYS2 CAL0006102 PMID: 10647122|CGD_REF: CAL0081494 homozygous diploid, classical genetics null lys2::hisG-URA3-hisG CAI-4 viable C. albicans orf19.2970 ORF LYS2 CAL0006102 PMID: 2050413|CGD_REF: CAL0080658 unknown ploidy, classical genetics unspecified Other C. albicans auxotrophy L-lysine C. albicans orf19.2970 ORF LYS2 CAL0006102 PMID: 2050413|CGD_REF: CAL0080658 unknown ploidy, classical genetics unspecified Other C. albicans viable C. albicans orf19.2970 ORF LYS2 CAL0006102 PMID: 21135205|CGD_REF: CAL0139967 heterozygous diploid, competitive growth (large-scale identification of genes essential for virulence in mouse) repressible CAI-4 virulence: normal mouse intravenous infection C. albicans orf19.2972 ORF PDE2 CAL0006104 PMID: 15789349|CGD_REF: CAL0104004 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased Calcofluor White C. albicans orf19.2972 ORF PDE2 CAL0006104 PMID: 15789349|CGD_REF: CAL0104004 heterozygous diploid, classical genetics null Not recorded resistance to chemicals: normal Calcofluor White C. albicans orf19.2972 ORF PDE2 CAL0006104 PMID: 14617167|CGD_REF: CAL0080818 heterozygous diploid, classical genetics overexpression CAI-4 germ tube formation: decreased C. albicans orf19.2972 ORF PDE2 CAL0006104 PMID: 14617167|CGD_REF: CAL0080818 homozygous diploid, classical genetics null Not recorded starvation resistance: decreased nutrient starvation C. albicans orf19.2972 ORF PDE2 CAL0006104 PMID: 17614954|CGD_REF: CAL0118240 homozygous diploid, classical genetics null Not recorded thermotolerance: decreased increased sensitivity to heat shock C. albicans orf19.2972 ORF PDE2 CAL0006104 PMID: 15789349|CGD_REF: CAL0104004 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased flucytosine C. albicans orf19.2972 ORF PDE2 CAL0006104 PMID: 15789349|CGD_REF: CAL0104004 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased sodium dodecyl sulfate C. albicans orf19.2972 ORF PDE2 CAL0006104 PMID: 15789349|CGD_REF: CAL0104004 heterozygous diploid, classical genetics null Not recorded resistance to chemicals: normal sodium dodecyl sulfate C. albicans orf19.2972 ORF PDE2 CAL0006104 PMID: 14523128|CGD_REF: CAL0081197 homozygous diploid, classical genetics null Not recorded heat sensitivity: increased C. albicans orf19.2972 ORF PDE2 CAL0006104 PMID: 14523128|CGD_REF: CAL0081197 homozygous diploid, classical genetics null CAI-4 hyphal growth: abnormal solid media abolished hyphal to yeast-form switching C. albicans orf19.2972 ORF PDE2 CAL0006104 PMID: 14523128|CGD_REF: CAL0081197 homozygous diploid, classical genetics null CAI-4 hyphal growth: abnormal solid YPD plus serum, Spider, agar-embedded, or GlcNAc media hyphae exhibit less branching and fewer buds C. albicans orf19.2972 ORF PDE2 CAL0006104 PMID: 14617167|CGD_REF: CAL0080818 homozygous diploid, classical genetics null CAI-4 hyphal growth: increased liquid M199, solid Spider, or solid serum-containing media rapid germ tube growth and increased hyphal length C. albicans orf19.2972 ORF PDE2 CAL0006104 PMID: 14523128|CGD_REF: CAL0081197 homozygous diploid, classical genetics null CAI-4 hyphal growth: absent serum- or GlcNAc-containing, Lee's pH 6.5, or Spider liquid media C. albicans orf19.2972 ORF PDE2 CAL0006104 PMID: 12773383|CGD_REF: CAL0087974 heterozygous diploid, classical genetics (haploinsufficient phenotype assay) null CAI-4 viable heterozygous deletion or transposon insertion C. albicans orf19.2972 ORF PDE2 CAL0006104 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.2972 ORF PDE2 CAL0006104 PMID: 14523128|CGD_REF: CAL0081197 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.2972 ORF PDE2 CAL0006104 PMID: 14617167|CGD_REF: CAL0080818 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.2972 ORF PDE2 CAL0006104 PMID: 17614954|CGD_REF: CAL0118240 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.2972 ORF PDE2 CAL0006104 PMID: 17614954|CGD_REF: CAL0118240 homozygous diploid, classical genetics null Not recorded acid pH resistance: decreased C. albicans orf19.2972 ORF PDE2 CAL0006104 PMID: 17614954|CGD_REF: CAL0118240 homozygous diploid, classical genetics null Not recorded adhesion: decreased adhesion to human buccal epithelial cells C. albicans orf19.2972 ORF PDE2 CAL0006104 PMID: 16407097|CGD_REF: CAL0115390 homozygous diploid, classical genetics null Not recorded apoptosis: increased slightly increased sensitivity to apoptosis-inducing stimuli C. albicans orf19.2972 ORF PDE2 CAL0006104 PMID: 14523128|CGD_REF: CAL0081197 homozygous diploid, classical genetics null CAI-4 invasive growth: increased solid Spider medium at 37 deg C C. albicans orf19.2972 ORF PDE2 CAL0006104 PMID: 14617167|CGD_REF: CAL0080818 homozygous diploid, classical genetics null CAI-4 invasive growth: abnormal solid YPD and YNB media C. albicans orf19.2972 ORF PDE2 CAL0006104 PMID: 17614954|CGD_REF: CAL0118240 homozygous diploid, classical genetics null Not recorded oxidative stress resistance: decreased hydrogen peroxide C. albicans orf19.2972 ORF PDE2 CAL0006104 PMID: 15789349|CGD_REF: CAL0104004 homozygous diploid, classical genetics null Not recorded cell wall morphology: abnormal cell wall is thinner than wild type C. albicans orf19.2972 ORF PDE2 CAL0006104 PMID: 15789349|CGD_REF: CAL0104004 homozygous diploid, classical genetics null Not recorded chemical compound accumulation: increased ergosterol C. albicans orf19.2972 ORF PDE2 CAL0006104 PMID: 14617167|CGD_REF: CAL0080818 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased 3',5'-cyclic AMP C. albicans orf19.2972 ORF PDE2 CAL0006104 PMID: 14523128|CGD_REF: CAL0081197 homozygous diploid, classical genetics null Not recorded chemical compound accumulation: increased 3',5'-cyclic AMP C. albicans orf19.2972 ORF PDE2 CAL0006104 PMID: 17614954|CGD_REF: CAL0118240 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased 1,4-dithiothreitol C. albicans orf19.2972 ORF PDE2 CAL0006104 PMID: 17614954|CGD_REF: CAL0118240 homozygous diploid, classical genetics null Not recorded metal resistance: decreased cadmium C. albicans orf19.2972 ORF PDE2 CAL0006104 PMID: 17614954|CGD_REF: CAL0118240 homozygous diploid, classical genetics null Not recorded ionic stress resistance: decreased sodium chloride C. albicans orf19.2972 ORF PDE2 CAL0006104 PMID: 15789349|CGD_REF: CAL0104004 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased amphotericin B C. albicans orf19.2972 ORF PDE2 CAL0006104 PMID: 14523128|CGD_REF: CAL0081197 homozygous diploid, classical genetics null Not recorded pseudohyphal growth: abnormal pseudohyphal growth occurs under hyphal growth-inducing conditions C. albicans orf19.2972 ORF PDE2 CAL0006104 PMID: 14523128|CGD_REF: CAL0081197 homozygous diploid, classical genetics null Not recorded pseudohyphal growth: increased in the presence of cAMP C. albicans orf19.2972 ORF PDE2 CAL0006104 PMID: 14523128|CGD_REF: CAL0081197 homozygous diploid, classical genetics null Not recorded pseudohyphal growth: increased liquid YPD or RPMI 1640 media, 30 deg C C. albicans orf19.2972 ORF PDE2 CAL0006104 PMID: 14523128|CGD_REF: CAL0081197 homozygous diploid, classical genetics null CAI-4 pseudohyphal growth: normal liquid YPD, 35 deg C C. albicans orf19.2972 ORF PDE2 CAL0006104 PMID: 14617167|CGD_REF: CAL0080818 homozygous diploid, classical genetics null Not recorded chemical compound accumulation: decreased glycogen upon entry into stationary phase C. albicans orf19.2972 ORF PDE2 CAL0006104 PMID: 17614954|CGD_REF: CAL0118240 homozygous diploid, classical genetics null Not recorded oxidative stress resistance: decreased menadione C. albicans orf19.2972 ORF PDE2 CAL0006104 PMID: 12773383|CGD_REF: CAL0087974 heterozygous diploid, classical genetics (haploinsufficient phenotype assay) null CAI-4 filamentous growth: increased solid Spider medium or solid YEPD plus serum heterozygous deletion or transposon insertion C. albicans orf19.2972 ORF PDE2 CAL0006104 PMID: 14617167|CGD_REF: CAL0080818 homozygous diploid, classical genetics null CAI-4 filamentous growth: abnormal filaments lack buds C. albicans orf19.2972 ORF PDE2 CAL0006104 PMID: 14617167|CGD_REF: CAL0080818 homozygous diploid, classical genetics null CAI-4 filamentous growth: increased solid YPD, liquid YPD, solid YNB, liquid YNB, solid Spider hyperfilamentous growth and filament aggregation C. albicans orf19.2972 ORF PDE2 CAL0006104 PMID: 14523128|CGD_REF: CAL0081197 homozygous diploid, classical genetics null CAI-4 filamentous growth: increased solid media C. albicans orf19.2972 ORF PDE2 CAL0006104 PMID: 17614954|CGD_REF: CAL0118240 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased tunicamycin C. albicans orf19.2972 ORF PDE2 CAL0006104 PMID: 15789349|CGD_REF: CAL0104004 homozygous diploid, classical genetics null Not recorded chemical compound accumulation: decreased glucan decreased cell wall glucan C. albicans orf19.2972 ORF PDE2 CAL0006104 PMID: 15789349|CGD_REF: CAL0104004 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased fluconazole C. albicans orf19.2972 ORF PDE2 CAL0006104 PMID: 14617167|CGD_REF: CAL0080818 homozygous diploid, classical genetics null Not recorded virulence: decreased mouse intravenous infection C. albicans orf19.2972 ORF PDE2 CAL0006104 PMID: 17614954|CGD_REF: CAL0118240 homozygous diploid, classical genetics null Not recorded virulence: decreased mouse intravenous infection C. albicans orf19.2973 ORF CAL0006105 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient YPD medium C. albicans orf19.2974 ORF YKT6 CAL0006106 PMID: 19040629|CGD_REF: CAL0121263 heterozygous diploid, classical genetics repressible CAI-4 hyphal growth: abnormal altered branching frequency in hyphae C. albicans orf19.2974 ORF YKT6 CAL0006106 PMID: 19040629|CGD_REF: CAL0121263 heterozygous diploid, classical genetics repressible CAI-4 hyphal growth: absent liquid serum-containing medium C. albicans orf19.2974 ORF YKT6 CAL0006106 PMID: 19040629|CGD_REF: CAL0121263 heterozygous diploid, classical genetics repressible Not recorded vacuolar morphology: abnormal diffuse vacuoles in yeast-like cells C. albicans orf19.2974 ORF YKT6 CAL0006106 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.2974 ORF YKT6 CAL0006106 PMID: 19040629|CGD_REF: CAL0121263 homozygous diploid, classical genetics null Not recorded inviable homozygous null mutant strain could not be recovered, suggesting that the gene is essential under the selection conditions C. albicans orf19.2974 ORF YKT6 CAL0006106 PMID: 19040629|CGD_REF: CAL0121263 heterozygous diploid, classical genetics repressible CAI-4 filamentous growth: abnormal agar-slide cultures with serum forms pseudohyphae instead of true hyphae C. albicans orf19.2975 ORF YPT7 CAL0006107 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.2975 ORF YPT7 CAL0006107 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.2975 ORF YPT7 CAL0006107 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: abnormal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.2975 ORF YPT7 CAL0006107 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.2975 ORF YPT7 CAL0006107 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.2977 ORF MIA40 CAL0006108 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.2978 ORF CAL0006109 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 invasive growth: decreased solid SLAD media C. albicans orf19.2983 ORF CDC73 CAL0006129 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.2984 ORF MST1 CAL0006130 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.2987 ORF CAL0006133 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.2988 ORF CAL0006134 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.2989 ORF GOR1 CAL0006135 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.299 ORF ECM14 CAL0004123 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.299 ORF ECM14 CAL0004123 PMID: 17873081|CGD_REF: CAL0118685 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.299 ORF ECM14 CAL0004123 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.299 ORF ECM14 CAL0004123 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: abnormal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.299 ORF ECM14 CAL0004123 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.299 ORF ECM14 CAL0004123 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.2990 ORF XOG1 CAL0006153 PMID: 9308184|CGD_REF: CAL0082037 homozygous diploid, classical genetics null Not recorded resistance to chemicals: normal miconazole C. albicans orf19.2990 ORF XOG1 CAL0006153 PMID: 9308184|CGD_REF: CAL0082037 homozygous diploid, classical genetics null CAI-4 hyphal growth: normal serum-containing or Lee's media C. albicans orf19.2990 ORF XOG1 CAL0006153 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.2990 ORF XOG1 CAL0006153 PMID: 14663094|CGD_REF: CAL0080633 homozygous diploid, systematic mutation set (homozygous insertion mutants generated with URA3-ARG4-URA3 (UAU1) cassette) null BWP17 viable C. albicans orf19.2990 ORF XOG1 CAL0006153 PMID: 14507372|CGD_REF: CAL0088818 heterozygous diploid, large-scale survey (large-scale identification of essential genes by gene replacement and conditional expression (GRACE) method) repressible CAI-4 viable one allele is deleted and the other is placed under repressible Tet promoter C. albicans orf19.2990 ORF XOG1 CAL0006153 PMID: 9308184|CGD_REF: CAL0082037 homozygous diploid, classical genetics null Not recorded viable wild-type growth rate C. albicans orf19.2990 ORF XOG1 CAL0006153 PMID: 9308184|CGD_REF: CAL0082037 heterozygous diploid, classical genetics null Not recorded viable C. albicans orf19.2990 ORF XOG1 CAL0006153 PMID: 9308184|CGD_REF: CAL0082037 heterozygous diploid, classical genetics null Not recorded protein activity: decreased activity is decreased by 40% of total exoglucanase C. albicans orf19.2990 ORF XOG1 CAL0006153 PMID: 9308184|CGD_REF: CAL0082037 homozygous diploid, classical genetics null Not recorded protein activity: decreased activity is decreased by 80% of total exoglucanase C. albicans orf19.2990 ORF XOG1 CAL0006153 PMID: 9308184|CGD_REF: CAL0082037 homozygous diploid, classical genetics null Not recorded resistance to chemicals: normal 2-deoxy-D-glucose C. albicans orf19.2990 ORF XOG1 CAL0006153 PMID: 9308184|CGD_REF: CAL0082037 homozygous diploid, classical genetics null Not recorded cellular morphology: normal C. albicans orf19.2990 ORF XOG1 CAL0006153 PMID: 9308184|CGD_REF: CAL0082037 homozygous diploid, classical genetics null Not recorded chitin deposition: increased increased staining with chitin-binding fluorochromes C. albicans orf19.2990 ORF XOG1 CAL0006153 PMID: 9308184|CGD_REF: CAL0082037 homozygous diploid, classical genetics null Not recorded resistance to chemicals: normal amphotericin B C. albicans orf19.2990 ORF XOG1 CAL0006153 PMID: 9308184|CGD_REF: CAL0082037 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased Cilofungin effect is slight C. albicans orf19.2990 ORF XOG1 CAL0006153 PMID: 9308184|CGD_REF: CAL0082037 homozygous diploid, classical genetics null Not recorded resistance to chemicals: normal canavanine C. albicans orf19.2990 ORF XOG1 CAL0006153 PMID: 9308184|CGD_REF: CAL0082037 homozygous diploid, classical genetics null Not recorded resistance to chemicals: normal trichodermin C. albicans orf19.2990 ORF XOG1 CAL0006153 PMID: 9308184|CGD_REF: CAL0082037 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased papulacandin B effect is slight C. albicans orf19.2990 ORF XOG1 CAL0006153 PMID: 9308184|CGD_REF: CAL0082037 homozygous diploid, classical genetics null Not recorded resistance to chemicals: increased nikkomycin Z C. albicans orf19.2990 ORF XOG1 CAL0006153 PMID: 22876186|CGD_REF: CAL0000157675 homozygous diploid, classical genetics null BWP17 biofilm formation: decreased C. albicans orf19.2990 ORF XOG1 CAL0006153 PMID: 22876186|CGD_REF: CAL0000157675 homozygous diploid, classical genetics null BWP17 resistance to chemicals: decreased fluconazole C. albicans orf19.2990 ORF XOG1 CAL0006153 PMID: 9308184|CGD_REF: CAL0082037 homozygous diploid, classical genetics null Not recorded virulence: decreased exhibits decreased brain colonization mouse intravenous infection C. albicans orf19.2990 ORF XOG1 CAL0006153 PMID: 9308184|CGD_REF: CAL0082037 homozygous diploid, classical genetics null Not recorded virulence: normal mouse intravenous infection C. albicans orf19.2991 ORF HOL1 CAL0006155 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.2991 ORF HOL1 CAL0006155 PMID: 14507372|CGD_REF: CAL0088818 heterozygous diploid, large-scale survey (large-scale identification of essential genes by gene replacement and conditional expression (GRACE) method) repressible CAI-4 viable one allele is deleted and the other is placed under repressible Tet promoter C. albicans orf19.2992 ORF RPP1A CAL0006156 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.2994 ORF RPL13 CAL0006157 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.2998 ORF TSR2 CAL0006160 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.30 ORF SPF1 CAL0000546 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: decreased growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.30 ORF SPF1 CAL0000546 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: abnormal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.30 ORF SPF1 CAL0000546 PMID: 22745267|CGD_REF: CAL0000157531 homozygous diploid, classical genetics null Other C. albicans viable C. albicans orf19.30 ORF SPF1 CAL0000546 PMID: 22745267|CGD_REF: CAL0000157531 homozygous diploid, classical genetics null Other C. albicans vegetative growth: decreased rate C. albicans orf19.30 ORF SPF1 CAL0000546 PMID: 22745267|CGD_REF: CAL0000157531 homozygous diploid, classical genetics null Other C. albicans resistance to chemicals: decreased ethylene glycol bis(2-aminoethyl)tetraacetate C. albicans orf19.30 ORF SPF1 CAL0000546 PMID: 22745267|CGD_REF: CAL0000157531 homozygous diploid, classical genetics null Other C. albicans metal resistance: decreased calcium(2+) (160 mM) C. albicans orf19.30 ORF SPF1 CAL0000546 PMID: 22745267|CGD_REF: CAL0000157531 homozygous diploid, classical genetics null Other C. albicans hyphal growth: decreased C. albicans orf19.30 ORF SPF1 CAL0000546 PMID: 22745267|CGD_REF: CAL0000157531 homozygous diploid, classical genetics null Other C. albicans biofilm formation: decreased polystyrene microtiter plates C. albicans orf19.30 ORF SPF1 CAL0000546 PMID: 22745267|CGD_REF: CAL0000157531 homozygous diploid, classical genetics null Other C. albicans virulence: decreased mouse intravenous infection C. albicans orf19.30 ORF SPF1 CAL0000546 PMID: 23731904|CGD_REF: CAL0000172373 homozygous diploid, classical genetics null spf1::ARG4/spf1::URA3-dpl200 Other C. albicans adhesion: decreased C. albicans orf19.30 ORF SPF1 CAL0000546 PMID: 23731904|CGD_REF: CAL0000172373 homozygous diploid, classical genetics null spf1::ARG4/spf1::URA3-dpl200 Other C. albicans flocculation: decreased C. albicans orf19.30 ORF SPF1 CAL0000546 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.30 ORF SPF1 CAL0000546 PMID: 23731904|CGD_REF: CAL0000172373 homozygous diploid, classical genetics null spf1::ARG4/spf1::URA3-dpl200 Other C. albicans protein/peptide modification: decreased N-linked glycosylation orf19.4014 C. albicans orf19.30 ORF SPF1 CAL0000546 PMID: 23731904|CGD_REF: CAL0000172373 homozygous diploid, classical genetics null spf1::ARG4/spf1::URA3-dpl200 Other C. albicans resistance to chemicals: decreased Calcofluor White C. albicans orf19.30 ORF SPF1 CAL0000546 PMID: 23731904|CGD_REF: CAL0000172373 homozygous diploid, classical genetics null spf1::ARG4/spf1::URA3-dpl200 Other C. albicans cell wall morphology: abnormal C. albicans orf19.30 ORF SPF1 CAL0000546 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.300 ORF AIP2 CAL0004623 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.3000 ORF ORC1 CAL0001320 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.3000 ORF ORC1 CAL0001320 PMID: 18179283|CGD_REF: CAL0119040 heterozygous diploid, classical genetics null Not recorded viable C. albicans orf19.3000 ORF ORC1 CAL0001320 PMID: 18179283|CGD_REF: CAL0119040 homozygous diploid, classical genetics null Not recorded inviable homozygous null mutant strain could not be recovered, suggesting that the gene is essential under the selection conditions C. albicans orf19.3001 ORF TEM1 CAL0001322 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.3001 ORF TEM1 CAL0001322 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient SC medium C. albicans orf19.3001 ORF TEM1 CAL0001322 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient YNB medium C. albicans orf19.3001 ORF TEM1 CAL0001322 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient SLAD medium C. albicans orf19.3001 ORF TEM1 CAL0001322 PMID: 21135205|CGD_REF: CAL0139967 heterozygous diploid, large-scale survey (large-scale identification of genes essential for virulence in mouse) repressible CAI-4 virulence: absent mouse intravenous infection C. albicans orf19.3002 ORF RPS1 CAL0001324 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.3002 ORF RPS1 CAL0001324 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient YPD medium C. albicans orf19.3002 ORF RPS1 CAL0001324 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient SC medium C. albicans orf19.3002 ORF RPS1 CAL0001324 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient YNB medium C. albicans orf19.3002 ORF RPS1 CAL0001324 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient SLAD medium C. albicans orf19.3003 ORF CAL0001326 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.3003.1 ORF RPL6 CAF0006876 PMID: 12773383|CGD_REF: CAL0087974 heterozygous diploid, classical genetics (haploinsufficient phenotype assay) unspecified CAI-4 filamentous growth: increased solid Spider medium transposon insertion proximal to, but not within, the ORF C. albicans orf19.3006 ORF GGA2 CAL0001331 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.3009 ORF CAL0001334 PMID: 14663094|CGD_REF: CAL0080633 homozygous diploid, systematic mutation set (homozygous insertion mutants generated with URA3-ARG4-URA3 (UAU1) cassette) null BWP17 viable C. albicans orf19.301 ORF PGA18 CAL0004624 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.301 ORF PGA18 CAL0004624 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.301 ORF PGA18 CAL0004624 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.301 ORF PGA18 CAL0004624 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.3010 ORF CAL0001338 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.3010.1 ORF ECM33 CAL0006505 PMID: 15470113|CGD_REF: CAL0082128 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased Calcofluor White C. albicans orf19.3010.1 ORF ECM33 CAL0006505 PMID: 15470113|CGD_REF: CAL0082128 homozygous diploid, classical genetics null Not recorded flocculation: increased C. albicans orf19.3010.1 ORF ECM33 CAL0006505 PMID: 16400176|CGD_REF: CAL0115367 heterozygous diploid, classical genetics null CAI-4 hyphal growth: normal endothelial cells or FaDu oral epithelial cell line in vitro model of infection C. albicans orf19.3010.1 ORF ECM33 CAL0006505 PMID: 16400176|CGD_REF: CAL0115367 homozygous diploid, classical genetics null CAI-4 hyphal growth: normal endothelial cells or FaDu oral epithelial cell line in vitro model of infection C. albicans orf19.3010.1 ORF ECM33 CAL0006505 PMID: 15470113|CGD_REF: CAL0082128 homozygous diploid, classical genetics null CAI-4 hyphal growth: absent solid Spider, SLADH, or serum-containing media C. albicans orf19.3010.1 ORF ECM33 CAL0006505 PMID: 16400176|CGD_REF: CAL0115367 heterozygous diploid, classical genetics null Not recorded vegetative growth: decreased rate rate is similar to that of homozygous null mutant C. albicans orf19.3010.1 ORF ECM33 CAL0006505 PMID: 16400176|CGD_REF: CAL0115367 homozygous diploid, classical genetics null Not recorded vegetative growth: decreased rate C. albicans orf19.3010.1 ORF ECM33 CAL0006505 PMID: 18546157|CGD_REF: CAL0119098 homozygous diploid, classical genetics null Not recorded viable URA3 restored during strain construction C. albicans orf19.3010.1 ORF ECM33 CAL0006505 PMID: 15470113|CGD_REF: CAL0082128 heterozygous diploid, classical genetics null Not recorded viable C. albicans orf19.3010.1 ORF ECM33 CAL0006505 PMID: 15470113|CGD_REF: CAL0082128 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.3010.1 ORF ECM33 CAL0006505 PMID: 16400176|CGD_REF: CAL0115367 homozygous diploid, classical genetics null Not recorded protein/peptide distribution: abnormal defect in Als1p localization to distinct band at base of hypha Als1p C. albicans orf19.3010.1 ORF ECM33 CAL0006505 PMID: 16400176|CGD_REF: CAL0115367 heterozygous diploid, classical genetics null Not recorded protein/peptide distribution: abnormal slight defect in Als1p localization to distinct band at base of hypha Als1p C. albicans orf19.3010.1 ORF ECM33 CAL0006505 PMID: 16400176|CGD_REF: CAL0115367 heterozygous diploid, classical genetics null Not recorded adhesion: decreased adhesion to endothelial cells or FaDu oral epithelial cell line phenotype is intermediate between that of wild type and the homozygous null mutant C. albicans orf19.3010.1 ORF ECM33 CAL0006505 PMID: 16400176|CGD_REF: CAL0115367 homozygous diploid, classical genetics null Not recorded adhesion: decreased adhesion to endothelial cells or FaDu oral epithelial cell line C. albicans orf19.3010.1 ORF ECM33 CAL0006505 PMID: 15470113|CGD_REF: CAL0082128 homozygous diploid, classical genetics null Not recorded cell size: increased cells are round and enlarged C. albicans orf19.3010.1 ORF ECM33 CAL0006505 PMID: 18546157|CGD_REF: CAL0119098 homozygous diploid, classical genetics null Not recorded cell wall morphology: abnormal altered pattern of surface-exposed proteins C. albicans orf19.3010.1 ORF ECM33 CAL0006505 PMID: 16400176|CGD_REF: CAL0115367 heterozygous diploid, classical genetics null Not recorded cell wall morphology: abnormal defect is intermediate between that of the homozygous null mutant and wild type C. albicans orf19.3010.1 ORF ECM33 CAL0006505 PMID: 16400176|CGD_REF: CAL0115367 homozygous diploid, classical genetics null Not recorded cell wall morphology: abnormal C. albicans orf19.3010.1 ORF ECM33 CAL0006505 PMID: 15470113|CGD_REF: CAL0082128 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased Congo Red C. albicans orf19.3010.1 ORF ECM33 CAL0006505 PMID: 15470113|CGD_REF: CAL0082128 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased Hygromycin B C. albicans orf19.3010.1 ORF ECM33 CAL0006505 PMID: 18546157|CGD_REF: CAL0119098 homozygous diploid, classical genetics null SC5314 induction of host response: abnormal mutant elicits enhanced TNFalpha response in vitro model of infection (RAW264.7 or mouse bone marrow derived macrophages) C. albicans orf19.3010.1 ORF ECM33 CAL0006505 PMID: 21407800|CGD_REF: CAL0141800 homozygous diploid, classical genetics null BWP17 interaction with host/environment: abnormal severely reduced invasion, and significantly reduced adhesion and damage to epithelial cells ex vivo model of infection C. albicans orf19.3010.1 ORF ECM33 CAL0006505 PMID: 22665950|CGD_REF: CAL0000157385 homozygous diploid, classical genetics null CAF2-1 biofilm formation: decreased C. albicans orf19.3010.1 ORF ECM33 CAL0006505 PMID: 16400176|CGD_REF: CAL0115367 homozygous diploid, classical genetics null Not recorded virulence: decreased endothelial cells or FaDu oral epithelial cell line decreased capacity to damage cells in vitro model of infection C. albicans orf19.3010.1 ORF ECM33 CAL0006505 PMID: 18546157|CGD_REF: CAL0119098 homozygous diploid, classical genetics null Not recorded virulence: absent strain is Ura+ mouse intravenous infection C. albicans orf19.3010.1 ORF ECM33 CAL0006505 PMID: 15470113|CGD_REF: CAL0082128 homozygous diploid, classical genetics null Not recorded virulence: decreased mouse intravenous infection C. albicans orf19.3010.1 ORF ECM33 CAL0006505 PMID: 18546157|CGD_REF: CAL0119098 homozygous diploid, classical genetics null Not recorded virulence: decreased mouse intravenous infection C. albicans orf19.3012 ORF ARO80 CAL0001342 PMID: 14663094|CGD_REF: CAL0080633 homozygous diploid, systematic mutation set (homozygous insertion mutants generated with URA3-ARG4-URA3 (UAU1) cassette) null BWP17 viable C. albicans orf19.3012 ORF ARO80 CAL0001342 PMID: 18836025|CGD_REF: CAL0120344 homozygous diploid, classical genetics null Not recorded chemical compound accumulation: decreased phenethyl alcohol C. albicans orf19.3012 ORF ARO80 CAL0001342 PMID: 18836025|CGD_REF: CAL0120344 homozygous diploid, classical genetics null Not recorded chemical compound accumulation: decreased tyrosol C. albicans orf19.3012 ORF ARO80 CAL0001342 PMID: 18836025|CGD_REF: CAL0120344 homozygous diploid, classical genetics null Not recorded chemical compound accumulation: decreased tryptophol C. albicans orf19.3012 ORF ARO80 CAL0001342 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.3012 ORF ARO80 CAL0001342 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: abnormal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.3012 ORF ARO80 CAL0001342 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.3012 ORF ARO80 CAL0001342 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.3013 ORF CDC12 CAL0001344 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.3013 ORF CDC12 CAL0001344 PMID: 22886998|CGD_REF: CAL0000157677 heterozygous diploid, classical genetics conditional cdc12-6/cdc12::ARG4 BWP17 filamentous growth: abnormal elevated temperatures (37 deg) C. albicans orf19.3013 ORF CDC12 CAL0001344 PMID: 12181342|CGD_REF: CAL0080842 homozygous diploid, classical genetics null Not recorded inviable homozygous null mutant strain could not be recovered, suggesting that the gene is essential under the selection conditions C. albicans orf19.3013 ORF CDC12 CAL0001344 PMID: 22886998|CGD_REF: CAL0000157677 heterozygous diploid, classical genetics conditional cdc12-6/cdc12::ARG4 BWP17 heat sensitivity: increased elevated temperatures (37 deg) C. albicans orf19.3013 ORF CDC12 CAL0001344 PMID: 22886998|CGD_REF: CAL0000157677 heterozygous diploid, classical genetics conditional cdc12-6/cdc12::ARG4 BWP17 bud morphology: abnormal elevated temperatures (37 deg) elongated buds C. albicans orf19.3014 ORF BMH1 CAL0001346 PMID: 15197733|CGD_REF: CAL0080799 heterozygous diploid, classical genetics null Other C. albicans germ tube formation: normal serum-containing or M199 media C. albicans orf19.3014 ORF BMH1 CAL0001346 PMID: 15197733|CGD_REF: CAL0080799 heterozygous diploid, classical genetics null Other C. albicans hyphal growth: normal solid Spider medium plus uridine hyphae are somewhat shorter than normal; supplemental uridine compensates for reduced URA3 expression C. albicans orf19.3014 ORF BMH1 CAL0001346 PMID: 11754483|CGD_REF: CAL0080797 heterozygous diploid, classical genetics null Not recorded hyphal growth: absent liquid M199 medium C. albicans orf19.3014 ORF BMH1 CAL0001346 PMID: 11754483|CGD_REF: CAL0080797 heterozygous diploid, classical genetics null Not recorded hyphal growth: normal liquid serum-containing medium C. albicans orf19.3014 ORF BMH1 CAL0001346 PMID: 11754483|CGD_REF: CAL0080797 heterozygous diploid, classical genetics null Not recorded hyphal growth: decreased solid M199, Spider, or serum-containing medium C. albicans orf19.3014 ORF BMH1 CAL0001346 PMID: 15184577|CGD_REF: CAL0080798 heterozygous diploid, classical genetics reduction of function Not recorded vegetative growth: decreased rate various point mutations cause slow growth to differing degrees: S188P (heat sensitive); K51E (ligand binding); L14Q, A15Q, E16R triple mutant (dimerization), L231S, and K51R C. albicans orf19.3014 ORF BMH1 CAL0001346 PMID: 11754483|CGD_REF: CAL0080797 heterozygous diploid, classical genetics null Not recorded vegetative growth: decreased rate solid or liquid media C. albicans orf19.3014 ORF BMH1 CAL0001346 PMID: 15184577|CGD_REF: CAL0080798 heterozygous diploid, classical genetics repressible Not recorded vegetative growth: decreased rate C. albicans orf19.3014 ORF BMH1 CAL0001346 PMID: 14663094|CGD_REF: CAL0080633 homozygous diploid, systematic mutation set (homozygous insertion mutants generated with URA3-ARG4-URA3 (UAU1) cassette) unspecified BWP17 viable homozygous insertion in 3' UTR C. albicans orf19.3014 ORF BMH1 CAL0001346 PMID: 12524333|CGD_REF: CAL0080691 homozygous diploid, systematic mutation set (homozygous insertion mutants generated with URA3-ARG4-URA3 (UAU1) cassette) null BWP17 viable homozygous insertion in 3' UTR C. albicans orf19.3014 ORF BMH1 CAL0001346 PMID: 11754483|CGD_REF: CAL0080797 heterozygous diploid, classical genetics null Not recorded viable C. albicans orf19.3014 ORF BMH1 CAL0001346 PMID: 15184577|CGD_REF: CAL0080798 heterozygous diploid, classical genetics reduction of function bmh1-L231S Not recorded chlamydospore formation: decreased hyperfilamentation is observed under chlamydospore-inducing conditions for L231S and K51E alleles C. albicans orf19.3014 ORF BMH1 CAL0001346 PMID: 15184577|CGD_REF: CAL0080798 heterozygous diploid, classical genetics reduction of function Not recorded resistance to chemicals: decreased rapamycin increased sensitivity to rapamycin (S188P or K51E at 37 deg C; L231S at 30 or 37 deg C) C. albicans orf19.3014 ORF BMH1 CAL0001346 PMID: 15184577|CGD_REF: CAL0080798 heterozygous diploid, classical genetics repressible Not recorded resistance to chemicals: increased rapamycin C. albicans orf19.3014 ORF BMH1 CAL0001346 PMID: 12524333|CGD_REF: CAL0080691 homozygous diploid, systematic mutation set (homozygous insertion mutants generated with URA3-ARG4-URA3 (UAU1) cassette) null BWP17 inviable homozygous null mutant strain could not be recovered, suggesting that the gene is essential under the selection conditions C. albicans orf19.3014 ORF BMH1 CAL0001346 PMID: 15197733|CGD_REF: CAL0080799 homozygous diploid, classical genetics null Not recorded inviable homozygous null mutant strain could not be recovered, suggesting that the gene is essential under the selection conditions C. albicans orf19.3014 ORF BMH1 CAL0001346 PMID: 11754483|CGD_REF: CAL0080797 homozygous diploid, classical genetics null Not recorded inviable C. albicans orf19.3014 ORF BMH1 CAL0001346 PMID: 15184577|CGD_REF: CAL0080798 heterozygous diploid, classical genetics null Not recorded chlamydospore formation: absent C. albicans orf19.3014 ORF BMH1 CAL0001346 PMID: 15197733|CGD_REF: CAL0080799 heterozygous diploid, classical genetics overexpression Not recorded utilization of carbon source: abnormal L-sorbose C. albicans orf19.3014 ORF BMH1 CAL0001346 PMID: 15197733|CGD_REF: CAL0080799 heterozygous diploid, classical genetics null Not recorded utilization of carbon source: increased L-sorbose C. albicans orf19.3014 ORF BMH1 CAL0001346 PMID: 15184577|CGD_REF: CAL0080798 heterozygous diploid, classical genetics unspecified BWP17 filamentous growth: abnormal several point mutations tested; mutants exhibit varying filamentation defects C. albicans orf19.3014 ORF BMH1 CAL0001346 PMID: 15184577|CGD_REF: CAL0080798 heterozygous diploid, classical genetics repressible BWP17 filamentous growth: decreased C. albicans orf19.3014 ORF BMH1 CAL0001346 PMID: 19372164|CGD_REF: CAL0122803 heterozygous diploid, classical genetics null bmh1-M125R BWP17 induction of host response: decreased host proinflammatory response is decreased mouse intravenous infection (BALB/c mice) C. albicans orf19.3014 ORF BMH1 CAL0001346 PMID: 19372164|CGD_REF: CAL0122803 heterozygous diploid, classical genetics reduction of function bmh1-K51E (similar results with bmh1-L231S) BWP17 virulence: decreased macrophage killing is attenuated in vitro model of infection (murine macrophage culture) C. albicans orf19.3014 ORF BMH1 CAL0001346 PMID: 15549319|CGD_REF: CAL0082476 heterozygous diploid, classical genetics reduction of function bmh1-K51R (similar results with bmh1-L231S) BWP17 filamentous growth: decreased solid M199, serum-containing medium, or chocolate agar with 5% CO2 mutant allele integrated at URA3 in bmh1 homozygous null background C. albicans orf19.3014 ORF BMH1 CAL0001346 PMID: 15549319|CGD_REF: CAL0082476 heterozygous diploid, classical genetics reduction of function bmh1-K51R (similar results with bmh1-L231S) BWP17 invasive growth: decreased embedded in YPS agar mutant allele integrated at URA3 in bmh1 homozygous null background C. albicans orf19.3014 ORF BMH1 CAL0001346 PMID: 15549319|CGD_REF: CAL0082476 heterozygous diploid, classical genetics reduction of function bmh1-L231S (similar results with bmh1-M125R) BWP17 heat sensitivity: increased elevated temperature (42 deg C) mutant allele integrated at URA3 in bmh1 homozygous null background C. albicans orf19.3014 ORF BMH1 CAL0001346 PMID: 15549319|CGD_REF: CAL0082476 heterozygous diploid, classical genetics reduction of function bmh1-L231S BWP17 vegetative growth: decreased rate permissive temperature (30 deg C) mutant allele integrated at URA3 in bmh1 homozygous null background C. albicans orf19.3014 ORF BMH1 CAL0001346 PMID: 15549319|CGD_REF: CAL0082476 heterozygous diploid, classical genetics reduction of function bmh1-L231S BWP17 resistance to chemicals: decreased rapamycin (10 nM) 30 or 37 deg C mutant allele integrated at URA3 in bmh1 homozygous null background C. albicans orf19.3014 ORF BMH1 CAL0001346 PMID: 15549319|CGD_REF: CAL0082476 heterozygous diploid, classical genetics reduction of function bmh1-M125R BWP17 resistance to chemicals: decreased rapamycin (10 nM) 37 deg C (rapamycin sensitivity is normal at 30 deg C) mutant allele integrated at URA3 in bmh1 homozygous null background C. albicans orf19.3014 ORF BMH1 CAL0001346 PMID: 15549319|CGD_REF: CAL0082476 heterozygous diploid, classical genetics reduction of function bmh1-L231S BWP17 chlamydospore formation: decreased cornmeal agar mutant allele integrated at URA3 in bmh1 homozygous null background C. albicans orf19.3014 ORF BMH1 CAL0001346 PMID: 15549319|CGD_REF: CAL0082476 heterozygous diploid, classical genetics reduction of function bmh1-R142C BWP17 chlamydospore formation: increased cornmeal agar mutant allele integrated at URA3 in bmh1 homozygous null background C. albicans orf19.3014 ORF BMH1 CAL0001346 PMID: 15549319|CGD_REF: CAL0082476 heterozygous diploid, classical genetics reduction of function bmh1-R142C BWP17 filamentous growth: increased cornmeal agar mutant allele integrated at URA3 in bmh1 homozygous null background C. albicans orf19.3016 ORF CAL0001350 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.302 ORF CAL0004625 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.3023 ORF NGG1 CAL0001366 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.3023 ORF NGG1 CAL0001366 PMID: 21135205|CGD_REF: CAL0139967 heterozygous diploid, competitive growth (large-scale identification of genes essential for virulence in mouse) repressible CAI-4 virulence: decreased mouse intravenous infection C. albicans orf19.3027 ORF CAL0001370 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.3029 ORF EHD3 CAL0001371 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.3029 ORF EHD3 CAL0001371 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.3029 ORF EHD3 CAL0001371 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: abnormal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.3029 ORF EHD3 CAL0001371 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.3029 ORF EHD3 CAL0001371 PMID: 24497638|CGD_REF: CAL0000173832 homozygous diploid, classical genetics null SC5314 utilization of carbon source: decreased propionate C. albicans orf19.3029 ORF EHD3 CAL0001371 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.3031 ORF SEC62 CAL0001383 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.3034 ORF RLI1 CAL0001388 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.3035 ORF CAL0001390 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.3037 ORF CAL0001392 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.3038 ORF TPS2 CAL0001393 PMID: 19231283|CGD_REF: CAL0122433 homozygous diploid, classical genetics null Not recorded heat sensitivity: increased 37 deg C slow growth at 37 deg C; no growth at 42 deg C C. albicans orf19.3038 ORF TPS2 CAL0001393 PMID: 11895938|CGD_REF: CAL0081983 homozygous diploid, classical genetics null Not recorded heat sensitivity: increased C. albicans orf19.3038 ORF TPS2 CAL0001393 PMID: 11988502|CGD_REF: CAL0081987 homozygous diploid, classical genetics null Not recorded hyphal growth: abnormal Spider medium hyphal growth is delayed C. albicans orf19.3038 ORF TPS2 CAL0001393 PMID: 11895938|CGD_REF: CAL0081983 homozygous diploid, classical genetics null Not recorded hyphal growth: normal various solid media or liquid media plus serum C. albicans orf19.3038 ORF TPS2 CAL0001393 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.3038 ORF TPS2 CAL0001393 PMID: 14507372|CGD_REF: CAL0088818 heterozygous diploid, large-scale survey (large-scale identification of essential genes by gene replacement and conditional expression (GRACE) method) repressible CAI-4 viable one allele is deleted and the other is placed under repressible Tet promoter C. albicans orf19.3038 ORF TPS2 CAL0001393 PMID: 11895938|CGD_REF: CAL0081983 heterozygous diploid, classical genetics null Not recorded viable C. albicans orf19.3038 ORF TPS2 CAL0001393 PMID: 11895938|CGD_REF: CAL0081983 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.3038 ORF TPS2 CAL0001393 PMID: 19231283|CGD_REF: CAL0122433 homozygous diploid, classical genetics null Not recorded oxidative stress resistance: decreased hydrogen peroxide C. albicans orf19.3038 ORF TPS2 CAL0001393 PMID: 19231283|CGD_REF: CAL0122433 homozygous diploid, classical genetics null Not recorded ionic stress resistance: decreased sodium chloride C. albicans orf19.3038 ORF TPS2 CAL0001393 PMID: 19231283|CGD_REF: CAL0122433 homozygous diploid, classical genetics null Other C. albicans resistance to killing by host cells: decreased in vitro model of infection (J774 macrophages) C. albicans orf19.3038 ORF TPS2 CAL0001393 PMID: 11895938|CGD_REF: CAL0081983 homozygous diploid, classical genetics null Not recorded virulence: decreased mouse intravenous infection C. albicans orf19.3038 ORF TPS2 CAL0001393 PMID: 11895938|CGD_REF: CAL0081983 heterozygous diploid, classical genetics null Not recorded virulence: normal mouse intravenous infection C. albicans orf19.3038 ORF TPS2 CAL0001393 PMID: 11988502|CGD_REF: CAL0081987 homozygous diploid, classical genetics null Not recorded virulence: decreased mouse intravenous infection C. albicans orf19.304 ORF CAL0004626 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.304 ORF CAL0004626 PMID: 21135205|CGD_REF: CAL0139967 heterozygous diploid, competitive growth (large-scale identification of genes essential for virulence in mouse) repressible CAI-4 virulence: normal mouse intravenous infection C. albicans orf19.3042 ORF CAL0001408 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.3045 ORF CAL0001411 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.3049 ORF CAL0001416 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.3049 ORF CAL0001416 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.3049 ORF CAL0001416 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.3049 ORF CAL0001416 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.3049 ORF CAL0001416 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.305 ORF CAL0004628 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.305 ORF CAL0004628 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.305 ORF CAL0004628 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.305 ORF CAL0004628 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.3051 ORF CAL0001429 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.3052 ORF YPT1 CAL0001430 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.3052 ORF YPT1 CAL0001430 PMID: 11429473|CGD_REF: CAL0081327 heterozygous diploid, classical genetics dominant negative Not recorded viable C. albicans orf19.3052 ORF YPT1 CAL0001430 PMID: 14507372|CGD_REF: CAL0088818 heterozygous diploid, large-scale survey (large-scale identification of essential genes by gene replacement and conditional expression (GRACE) method) repressible CAI-4 inviable one allele is deleted and the other is placed under repressible Tet promoter C. albicans orf19.3052 ORF YPT1 CAL0001430 PMID: 11429473|CGD_REF: CAL0081327 homozygous diploid, classical genetics null Not recorded inviable homozygous null mutant strain could not be recovered, suggesting that the gene is essential under the selection conditions C. albicans orf19.3052 ORF YPT1 CAL0001430 PMID: 16178371|CGD_REF: CAL0114737 heterozygous diploid, classical genetics dominant negative ypt1-N121I Not recorded protein transport: abnormal mislocalization of Cdr1p, Ftr1p, Mlt1p, but not Cdc10p, Int1p C. albicans orf19.3052 ORF YPT1 CAL0001430 PMID: 11429473|CGD_REF: CAL0081327 heterozygous diploid, classical genetics dominant negative Not recorded endomembrane system morphology: abnormal accumulation of intracellular secretory vesicles C. albicans orf19.3052 ORF YPT1 CAL0001430 PMID: 11429473|CGD_REF: CAL0081327 heterozygous diploid, classical genetics dominant negative Not recorded protein secretion: decreased decreased secreted aspartyl protease activity C. albicans orf19.3052 ORF YPT1 CAL0001430 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, competitive growth (haploinsufficient phenotype assay, barcode deletion set) null SC5314 resistance to chemicals: decreased terbinafine C. albicans orf19.3054 ORF RPN3 CAL0001433 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.3055 ORF MED17 CAL0001435 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.3055 ORF MED17 CAL0001435 PMID: 21135205|CGD_REF: CAL0139967 heterozygous diploid, competitive growth (large-scale identification of genes essential for virulence in mouse) repressible CAI-4 virulence: decreased mouse intravenous infection C. albicans orf19.3058 ORF COQ6 CAL0001438 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.3059 ORF SUA71 CAL0001439 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.3059 ORF SUA71 CAL0001439 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient YPD medium C. albicans orf19.3060 ORF CAL0001449 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.3060 ORF CAL0001449 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.3060 ORF CAL0001449 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: abnormal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.3060 ORF CAL0001449 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.3060 ORF CAL0001449 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.3062 ORF CAL0001454 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.3063 ORF HFL1 CAL0001456 PMID: 20041210|CGD_REF: CAL0124764 homozygous diploid, systematic mutation set null SN152 vegetative growth: decreased SD or YEPD media at 30 deg C, or blood agar at 37 deg C strongly decreased C. albicans orf19.3063 ORF HFL1 CAL0001456 PMID: 20041210|CGD_REF: CAL0124764 homozygous diploid, systematic mutation set null SN152 invasive growth: increased YEPD medium at 30 deg C strongly increased C. albicans orf19.3063 ORF HFL1 CAL0001456 PMID: 20041210|CGD_REF: CAL0124764 homozygous diploid, systematic mutation set null SN152 colony color: abnormal CHROMagar medium at 30 deg C darker than normal C. albicans orf19.3063 ORF HFL1 CAL0001456 PMID: 24450762|CGD_REF: CAL0000173762 homozygous diploid, classical genetics null Other C. albicans viable C. albicans orf19.3063 ORF HFL1 CAL0001456 PMID: 24450762|CGD_REF: CAL0000173762 homozygous diploid, classical genetics null Other C. albicans vegetative growth: decreased rate C. albicans orf19.3063 ORF HFL1 CAL0001456 PMID: 24450762|CGD_REF: CAL0000173762 homozygous diploid, classical genetics null Other C. albicans colony shape: abnormal C. albicans orf19.3063 ORF HFL1 CAL0001456 PMID: 24450762|CGD_REF: CAL0000173762 homozygous diploid, classical genetics null Other C. albicans invasive growth: decreased C. albicans orf19.3063 ORF HFL1 CAL0001456 PMID: 24450762|CGD_REF: CAL0000173762 homozygous diploid, classical genetics null Other C. albicans resistance to chemicals: decreased fluconazole C. albicans orf19.3063 ORF HFL1 CAL0001456 PMID: 24450762|CGD_REF: CAL0000173762 homozygous diploid, classical genetics null Other C. albicans resistance to chemicals: decreased Calcofluor White C. albicans orf19.3063 ORF HFL1 CAL0001456 PMID: 24450762|CGD_REF: CAL0000173762 homozygous diploid, classical genetics null Other C. albicans resistance to chemicals: decreased caspofungin C. albicans orf19.3063 ORF HFL1 CAL0001456 PMID: 24450762|CGD_REF: CAL0000173762 homozygous diploid, classical genetics null Other C. albicans resistance to chemicals: decreased Congo Red C. albicans orf19.3063 ORF HFL1 CAL0001456 PMID: 24450762|CGD_REF: CAL0000173762 homozygous diploid, classical genetics null Other C. albicans respiratory growth: decreased rate C. albicans orf19.3064 ORF MRPL27 CAL0001458 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.3065 ORF DAO1 CAL0001460 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.3065 ORF DAO1 CAL0001460 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient SC medium C. albicans orf19.3066 ORF ENG1 CAL0001461 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.3066 ORF ENG1 CAL0001461 PMID: 16328626|CGD_REF: CAL0115073 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.3066 ORF ENG1 CAL0001461 PMID: 16328626|CGD_REF: CAL0115073 homozygous diploid, classical genetics null Not recorded cytokinesis: absent C. albicans orf19.3066 ORF ENG1 CAL0001461 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.3066 ORF ENG1 CAL0001461 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: abnormal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.3066 ORF ENG1 CAL0001461 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.3066 ORF ENG1 CAL0001461 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.3071 ORF MIH1 CAL0001477 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.3071 ORF MIH1 CAL0001477 PMID: 18708562|CGD_REF: CAL0119375 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.3071 ORF MIH1 CAL0001477 PMID: 18708562|CGD_REF: CAL0119375 homozygous diploid, classical genetics null Not recorded virulence: normal silkworm insect infection C. albicans orf19.3077 ORF VID21 CAL0001486 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 invasive growth: decreased solid SLAD media C. albicans orf19.308 ORF CAL0004634 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.3080 ORF CAL0001496 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.3083 ORF CAL0001501 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.3086 ORF SEC10 CAL0001505 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.3087 ORF UBI3 CAL0001506 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.3087 ORF UBI3 CAL0001506 PMID: 11054822|CGD_REF: CAL0082004 homozygous diploid, classical genetics null Not recorded inviable homozygous null mutant strain could not be recovered, suggesting that the gene is essential under the selection conditions C. albicans orf19.3087 ORF UBI3 CAL0001506 PMID: 12702318|CGD_REF: CAL0081529 homozygous diploid, classical genetics null Not recorded inviable C. albicans orf19.3088 ORF CAL0001507 PMID: 15964282|CGD_REF: CAL0114274 homozygous diploid, systematic mutation set (split-marker transposon insertion strategy to disrupt both alleles) null BWP17 viable C. albicans orf19.3088 ORF CAL0001507 PMID: 15964282|CGD_REF: CAL0114274 homozygous diploid, systematic mutation set (split-marker transposon insertion strategy to disrupt both alleles) null BWP17 biofilm formation: normal C. albicans orf19.3089 ORF CAL0001508 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.3089 ORF CAL0001508 PMID: 23572557|CGD_REF: CAL0000158900 homozygous diploid, classical genetics null BWP17 adhesion: decreased Fluxion Bioflux 200, equipped with a microscope, was used for adherence analysis allowing a constant flow of cells through microfluidic channels C. albicans orf19.3089 ORF CAL0001508 PMID: 23572557|CGD_REF: CAL0000158900 homozygous diploid, classical genetics null BWP17 resistance to chemicals: increased fluconazole RPMI+MOPS+Histidine medium , 6 hours without shaking at 37 degrees C 24 hr fluconazole treatment in 96 well plates C. albicans orf19.309 ORF DAL5 CAL0004637 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.309 ORF DAL5 CAL0004637 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient YPD medium C. albicans orf19.309 ORF DAL5 CAL0004637 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient SLAD medium C. albicans orf19.3091 ORF CAL0001522 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 invasive growth: decreased solid SLAD media C. albicans orf19.3093 ORF MSH2 CAL0001526 PMID: 17965250|CGD_REF: CAL0118884 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.3097 ORF PDA1 CAL0001531 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.3098 ORF CAL0001532 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.3099 ORF TRP4 CAL0001533 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.3099 ORF TRP4 CAL0001533 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 invasive growth: decreased solid SLAD media C. albicans orf19.310 ORF CAL0004660 PMID: 17873081|CGD_REF: CAL0118685 homozygous diploid, classical genetics null Not recorded inviable homozygous null mutant strain could not be recovered, suggesting that the gene is essential under the selection conditions C. albicans orf19.3100 ORF CAL0002211 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.3100 ORF CAL0002211 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient SC medium C. albicans orf19.3100 ORF CAL0002211 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 invasive growth: decreased solid SLAD media C. albicans orf19.3103 ORF CAL0002215 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.3104 ORF YDC1 CAL0002217 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.3105 ORF CAL0002219 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.3105 ORF CAL0002219 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.3105 ORF CAL0002219 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.3105 ORF CAL0002219 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.3105 ORF CAL0002219 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.3106 ORF MET16 CAL0002221 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.3106 ORF MET16 CAL0002221 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, competitive growth (haploinsufficient phenotype assay, barcode deletion set) null SC5314 resistance to chemicals: decreased amphotericin B C. albicans orf19.3106 ORF MET16 CAL0002221 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, competitive growth (haploinsufficient phenotype assay, barcode deletion set) null SC5314 resistance to chemicals: decreased ergosterol analogs (ECC69 and/or ECC1384) C. albicans orf19.3106 ORF MET16 CAL0002221 PMID: 21135205|CGD_REF: CAL0139967 heterozygous diploid, competitive growth (large-scale identification of genes essential for virulence in mouse) repressible CAI-4 virulence: normal mouse intravenous infection C. albicans orf19.3108 ORF CAL0002223 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.3108 ORF CAL0002223 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.3108 ORF CAL0002223 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.3108 ORF CAL0002223 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.3111 ORF PRA1 CAL0002231 PMID: 9440517|CGD_REF: CAL0081753 homozygous diploid, classical genetics null Not recorded germ tube formation: decreased serum-containing or Lee's media C. albicans orf19.3111 ORF PRA1 CAL0002231 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.3111 ORF PRA1 CAL0002231 PMID: 18625733|CGD_REF: CAL0119341 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.3111 ORF PRA1 CAL0002231 PMID: 9440517|CGD_REF: CAL0081753 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.3111 ORF PRA1 CAL0002231 PMID: 17277107|CGD_REF: CAL0117291 homozygous diploid, classical genetics null Not recorded adhesion: decreased adhesion to THP-1 monocytoid cells C. albicans orf19.3111 ORF PRA1 CAL0002231 PMID: 14507372|CGD_REF: CAL0088818 heterozygous diploid, large-scale survey (large-scale identification of essential genes by gene replacement and conditional expression (GRACE) method) repressible CAI-4 inviable one allele is deleted and the other is placed under repressible Tet promoter C. albicans orf19.3111 ORF PRA1 CAL0002231 PMID: 9440517|CGD_REF: CAL0081753 homozygous diploid, classical genetics null Not recorded cellular morphology: abnormal C. albicans orf19.3111 ORF PRA1 CAL0002231 PMID: 21245270|CGD_REF: CAL0141197 homozygous diploid, classical genetics null Other C. albicans virulence: increased mouse intravenous infection C. albicans orf19.3111 ORF PRA1 CAL0002231 PMID: 21245270|CGD_REF: CAL0141197 homozygous diploid, classical genetics null Other C. albicans adhesion: decreased peritoneal PMNs and and HEK293/alphaMbeta2 cells (Human Embryonic Kidney cell line 293 159 expressing alphaMbeta2 on their surface) C. albicans orf19.3111 ORF PRA1 CAL0002231 PMID: 21245270|CGD_REF: CAL0141197 homozygous diploid, classical genetics null Other C. albicans induction of host response: decreased peritoneal PMNs absence of peritoneal PMN migration toward pra1 mutants C. albicans orf19.3111 ORF PRA1 CAL0002231 PMID: 17277107|CGD_REF: CAL0117291 homozygous diploid, classical genetics null Other C. albicans resistance to killing by host cells: increased increased resistance to PMN-mediated killing in vitro model of infection (human polymorphonuclear leukocytes) C. albicans orf19.3111 ORF PRA1 CAL0002231 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.3111 ORF PRA1 CAL0002231 PMID: 21245270|CGD_REF: CAL0141197 homozygous diploid, classical genetics null Other C. albicans resistance to killing by host cells: increased 32% of wild-type control remained viable whereas 88% of pra1 mutants retained viability in vitro model of infection (peritoneal PMNs) C. albicans orf19.3111 ORF PRA1 CAL0002231 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.3111 ORF PRA1 CAL0002231 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.3111 ORF PRA1 CAL0002231 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.3112 ORF ZRT1 CAL0002233 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.3112 ORF ZRT1 CAL0002233 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.3112 ORF ZRT1 CAL0002233 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.3112 ORF ZRT1 CAL0002233 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.3112 ORF ZRT1 CAL0002233 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.3116 ORF EXM2 CAL0002241 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.3116 ORF EXM2 CAL0002241 PMID: 21135205|CGD_REF: CAL0139967 heterozygous diploid, large-scale survey (large-scale identification of genes essential for virulence in mouse) repressible CAI-4 virulence: absent mouse intravenous infection C. albicans orf19.3117 ORF CSA2 CAF0006972 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.3117 ORF CSA2 CAF0006972 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.3117 ORF CSA2 CAF0006972 PMID: 23563485|CGD_REF: CAL0000158903 homozygous diploid, classical genetics null a/apha csa2::FRT/csa2::FRT SC5314 biofilm formation: abnormal RPMI medium 29 degrees C with rocking for 48 hr mutants have reduced vertical orientation of hyphae, an abnormal extracellular matrix, complete penetrabity to Sypro Ruby and human PMNs and increased sensitivity to fluconazole C. albicans orf19.3117 ORF CSA2 CAF0006972 PMID: 23563485|CGD_REF: CAL0000158903 heterozygous diploid, classical genetics repressible a/alpha csa2::FRT/csa2::FRT ADH1/adh1::pTET-CSA2::SATR SC5314 biofilm formation: abnormal RPMI medium 29 degrees C with rocking for 48 hr mutant has minor defects in vertical orientation of hyphae, complete permeability to Sypro Ruby and human PMNs and decreased fluconazole resistance C. albicans orf19.3117 ORF CSA2 CAF0006972 PMID: 23563485|CGD_REF: CAL0000158903 heterozygous diploid, classical genetics repressible a/a ADH1/adh1::pTET-CSA2::SATR (tet repressed) P37005 biofilm formation: abnormal RPMI medium 29 degrees C with rocking for 48 hr ecreased Sypro Ruby and human PMN penetrability, decreased resistance to fluconazole C. albicans orf19.3117 ORF CSA2 CAF0006972 PMID: 24796871|CGD_REF: CAL0000173858 homozygous diploid, classical genetics null BWP17 utilization of iron source: decreased iron trichloride C. albicans orf19.3117 ORF CSA2 CAF0006972 PMID: 24796871|CGD_REF: CAL0000173858 homozygous diploid, classical genetics null BWP17 utilization of iron source: decreased human hemoglobin C. albicans orf19.3117 ORF CSA2 CAF0006972 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.3117 ORF CSA2 CAF0006972 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.3120 ORF CAL0002254 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.3121 ORF GST1 CAL0002257 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.3122 ORF ARR3 CAL0002260 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.3122 ORF ARR3 CAL0002260 PMID: 14663094|CGD_REF: CAL0080633 homozygous diploid, systematic mutation set (homozygous insertion mutants generated with URA3-ARG4-URA3 (UAU1) cassette) null BWP17 viable C. albicans orf19.3122 ORF ARR3 CAL0002260 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.3122 ORF ARR3 CAL0002260 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.3122 ORF ARR3 CAL0002260 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.3122 ORF ARR3 CAL0002260 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.3123 ORF RPT5 CAL0002261 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.3123 ORF RPT5 CAL0002261 PMID: 20494978|CGD_REF: CAL0125636 heterozygous diploid, classical genetics null BWP17 resistance to chemicals: decreased clotrimazole (75 uM) growth in liquid culture confirmation of mutant phenotypes for heterozygous transposon insertion strains showing sensitivity in a large-scale assay C. albicans orf19.3123.2 ORF CAF0006974 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 invasive growth: decreased solid SLAD media C. albicans orf19.3124 ORF CAL0002263 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.3124 ORF CAL0002263 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 invasive growth: decreased solid SLAD media C. albicans orf19.3125 ORF CAL0002265 PMID: 14663094|CGD_REF: CAL0080633 homozygous diploid, systematic mutation set (homozygous insertion mutants generated with URA3-ARG4-URA3 (UAU1) cassette) null BWP17 viable C. albicans orf19.3126 ORF CCT6 CAL0002267 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.3126 ORF CCT6 CAL0002267 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, competitive growth (haploinsufficient phenotype assay, barcode deletion set) null SC5314 resistance to chemicals: decreased cytochalasin D C. albicans orf19.3127 ORF CZF1 CAL0002268 PMID: 12773383|CGD_REF: CAL0087974 heterozygous diploid, classical genetics (haploinsufficient phenotype assay) null CAI-4 viable heterozygous transposon insertion C. albicans orf19.3127 ORF CZF1 CAL0002268 PMID: 15964282|CGD_REF: CAL0114274 homozygous diploid, systematic mutation set (split-marker transposon insertion strategy to disrupt both alleles) null BWP17 viable C. albicans orf19.3127 ORF CZF1 CAL0002268 PMID: 10564506|CGD_REF: CAL0081058 homozygous diploid, classical genetics overexpression CAI-4 viable C. albicans orf19.3127 ORF CZF1 CAL0002268 PMID: 10564506|CGD_REF: CAL0081058 homozygous diploid, classical genetics null czf1::hisG/czf1::hisG-URA3-hisG CAI-4 filamentous growth: decreased growth condition-specific C. albicans orf19.3127 ORF CZF1 CAL0002268 PMID: 10564506|CGD_REF: CAL0081058 homozygous diploid, classical genetics null czf1::hisG/czf1::hisG-URA3-hisG CAI-4 filamentous growth: delayed embedded in YPS agar, 25 deg C C. albicans orf19.3127 ORF CZF1 CAL0002268 PMID: 10564506|CGD_REF: CAL0081058 homozygous diploid, classical genetics null czf1::hisG/czf1::hisG-URA3-hisG CAI-4 viable C. albicans orf19.3127 ORF CZF1 CAL0002268 PMID: 15964282|CGD_REF: CAL0114274 homozygous diploid, systematic mutation set (split-marker transposon insertion strategy to disrupt both alleles) null BWP17 biofilm formation: normal C. albicans orf19.3127 ORF CZF1 CAL0002268 PMID: 22761849|CGD_REF: CAL0000157576 aneuploid, classical genetics reduction of function czf1-R321A (similar results with czf1-K322A) CAI-4 invasive growth: decreased C. albicans orf19.3127 ORF CZF1 CAL0002268 PMID: 22761849|CGD_REF: CAL0000157576 aneuploid, classical genetics reduction of function czf1-R321A (similar results with czf1-K322A) CAI-4 filamentous growth: decreased C. albicans orf19.3127 ORF CZF1 CAL0002268 PMID: 12773383|CGD_REF: CAL0087974 heterozygous diploid, classical genetics (haploinsufficient phenotype assay) null CAI-4 filamentous growth: increased solid Spider medium or solid YEPD plus serum heterozygous transposon insertion C. albicans orf19.3127 ORF CZF1 CAL0002268 PMID: 10564506|CGD_REF: CAL0081058 homozygous diploid, classical genetics overexpression CAI-4 filamentous growth: increased embedded in agar C. albicans orf19.3127 ORF CZF1 CAL0002268 PMID: 9593148|CGD_REF: CAL0103098 unknown ploidy, classical genetics overexpression WO-1 phenotypic switching: increased white-to-opaque switching C. albicans orf19.3127 ORF CZF1 CAL0002268 PMID: 18551173|CGD_REF: CAL0119102 homozygous diploid, classical genetics null WO-1 phenotypic switching: abnormal decreased induction of white-to-opaque switching under anaerobic conditions C. albicans orf19.3127 ORF CZF1 CAL0002268 PMID: 18551173|CGD_REF: CAL0119102 heterozygous diploid, classical genetics misexpression WO-1 phenotypic switching: increased white-to-opaque switching C. albicans orf19.3127 ORF CZF1 CAL0002268 PMID: 17880264|CGD_REF: CAL0118619 homozygous diploid, classical genetics null CAI-4 viable C. albicans orf19.3127 ORF CZF1 CAL0002268 PMID: 19463063|CGD_REF: CAL0123630 homozygous diploid, classical genetics null BWP17 viable C. albicans orf19.3127 ORF CZF1 CAL0002268 PMID: 19200725|CGD_REF: CAL0122386 homozygous diploid, classical genetics null czf1::FRT/czf1::FRT WO-1 phenotypic switching: decreased decreased induction of white-to-opaque switching by CO2 C. albicans orf19.3127 ORF CZF1 CAL0002268 PMID: 19200725|CGD_REF: CAL0122386 homozygous diploid, classical genetics null CAI-4 phenotypic switching: decreased MTLa/MTLa background white-to-opaque switching (50-fold reduction) C. albicans orf19.3127 ORF CZF1 CAL0002268 PMID: 19200725|CGD_REF: CAL0122386 heterozygous diploid, classical genetics misexpression CAI-4 phenotypic switching: increased MTLa/MTLa background white-to-opaque switching C. albicans orf19.3127 ORF CZF1 CAL0002268 PMID: 21407800|CGD_REF: CAL0141800 homozygous diploid, classical genetics null BWP17 interaction with host/environment: abnormal significantly reduces adhesion, invasion, and damage to epithelial cells ex vivo model of infection C. albicans orf19.3127 ORF CZF1 CAL0002268 PMID: 22073120|CGD_REF: CAL0000143592 homozygous diploid, classical genetics null BWP17 viable C. albicans orf19.3127 ORF CZF1 CAL0002268 PMID: 22073120|CGD_REF: CAL0000143592 homozygous diploid, classical genetics null BWP17 colony appearance: abnormal increased colony wrinkling C. albicans orf19.3127 ORF CZF1 CAL0002268 PMID: 22359502|CGD_REF: CAL0000144048 homozygous diploid, classical genetics null BWP17 viable insertion mutant, independent SN152 deletion mutant strain also tested C. albicans orf19.3127 ORF CZF1 CAL0002268 PMID: 22359502|CGD_REF: CAL0000144048 homozygous diploid, classical genetics null BWP17 adhesion: decreased insertion mutant, independent SN152 deletion mutant strain also tested C. albicans orf19.3127 ORF CZF1 CAL0002268 PMID: 23873867|CGD_REF: CAL0000172545 homozygous diploid, classical genetics null czf1::hisG/czf1::hisG CAI-4 resistance to chemicals: increased farnesol C. albicans orf19.3127 ORF CZF1 CAL0002268 PMID: 19463063|CGD_REF: CAL0123630 homozygous diploid, systematic mutation set (split-marker transposon insertion strategy to disrupt both alleles) null BWP17 virulence: normal Toll mutant D. melanogaster invasive infection insect infection C. albicans orf19.3127 ORF CZF1 CAL0002268 PMID: 23808664|CGD_REF: CAL0000172530 homozygous diploid, systematic mutation set null CAI-4 filamentous growth: increased Lee's glucose medium at 25 deg opaque cells C. albicans orf19.3128 ORF CAL0002269 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.3129 ORF CAL0002270 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.3129 ORF CAL0002270 PMID: 19115836|CGD_REF: CAL0122036 heterozygous diploid, competitive growth (haploinsufficient phenotype assay, barcode deletion set) null SC5314 resistance to chemicals: decreased virgineone C. albicans orf19.3129 ORF CAL0002270 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient YPD medium C. albicans orf19.3129 ORF CAL0002270 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient SLAD medium C. albicans orf19.313 ORF DAL4 CAL0004663 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.3130 ORF CAL0002280 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.3131 ORF OYE32 CAL0002283 PMID: 17531199|CGD_REF: CAL0118028 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.3131 ORF OYE32 CAL0002283 PMID: 20017731|CGD_REF: CAL0124891 homozygous diploid, classical genetics null Other C. albicans resistance to chemicals: decreased cucurminoids (74 mg/l) C. albicans orf19.3133 ORF GUT2 CAL0002288 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient YPD medium C. albicans orf19.3133 ORF GUT2 CAL0002288 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient YNB medium C. albicans orf19.3138 ORF NOP1 CAL0002295 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient YPD medium C. albicans orf19.3138 ORF NOP1 CAL0002295 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient SLAD medium C. albicans orf19.3138 ORF NOP1 CAL0002295 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 invasive growth: decreased solid SLAD media C. albicans orf19.3139 ORF CAL0002296 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.314 ORF CAL0004664 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.3149 ORF LSP1 CAL0002322 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.3150 ORF GRE2 CAL0002333 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.3152 ORF AMO2 CAL0002338 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.3152 ORF AMO2 CAL0002338 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, competitive growth (haploinsufficient phenotype assay, barcode deletion set) null SC5314 resistance to chemicals: decreased ergosterol analogs (ECC69 and/or ECC1384) C. albicans orf19.3153 ORF MSS4 CAL0002340 PMID: 22891265|CGD_REF: CAL0000157680 heterozygous diploid, classical genetics repressible mss4/pTetMSS4 BWP17 viable repressive conditions, doxycycline C. albicans orf19.3153 ORF MSS4 CAL0002340 PMID: 22891265|CGD_REF: CAL0000157680 heterozygous diploid, classical genetics repressible mss4/pTetMSS4 BWP17 invasive growth: decreased repressive conditions, doxycycline C. albicans orf19.3156 ORF CAL0002344 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.3156 ORF CAL0002344 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.3156 ORF CAL0002344 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.3156 ORF CAL0002344 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.3156 ORF CAL0002344 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.3156 ORF CAL0002344 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.3156 ORF CAL0002344 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.3156 ORF CAL0002344 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.3156 ORF CAL0002344 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.3159 ORF UTP20 CAL0002346 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, competitive growth (haploinsufficient phenotype assay, barcode deletion set) null SC5314 resistance to chemicals: increased flucytosine C. albicans orf19.3159 ORF UTP20 CAL0002346 PMID: 12524333|CGD_REF: CAL0080691 homozygous diploid, systematic mutation set (homozygous insertion mutants generated with URA3-ARG4-URA3 (UAU1) cassette) null BWP17 inviable homozygous null mutant strain could not be recovered, suggesting that the gene is essential under the selection conditions C. albicans orf19.3159 ORF UTP20 CAL0002346 PMID: 19623926|CGD_REF: CAL0124054 heterozygous diploid, competitive growth (haploinsufficient phenotype assay, barcode deletion set) null SC5314 resistance to chemicals: increased parnafungin C. albicans orf19.316 ORF SEC13 CAL0004667 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.3161 ORF CAL0002361 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.3161 ORF CAL0002361 PMID: 21135205|CGD_REF: CAL0139967 heterozygous diploid, large-scale survey (large-scale identification of genes essential for virulence in mouse) repressible CAI-4 virulence: absent mouse intravenous infection C. albicans orf19.3166 ORF CAL0002369 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.3168 ORF RPN8 CAL0002371 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.3168 ORF RPN8 CAL0002371 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, competitive growth (haploinsufficient phenotype assay, barcode deletion set) null SC5314 resistance to chemicals: decreased amphotericin B C. albicans orf19.3169 ORF CAL0002372 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.3170 ORF CAL0002385 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 invasive growth: decreased solid SLAD media C. albicans orf19.3171 ORF ACH1 CAL0002388 PMID: 14663094|CGD_REF: CAL0080633 homozygous diploid, systematic mutation set (homozygous insertion mutants generated with URA3-ARG4-URA3 (UAU1) cassette) null BWP17 viable C. albicans orf19.3171 ORF ACH1 CAL0002388 PMID: 18689527|CGD_REF: CAL0119372 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.3171 ORF ACH1 CAL0002388 PMID: 18689527|CGD_REF: CAL0119372 homozygous diploid, classical genetics null Not recorded utilization of carbon source: decreased acetic acid C. albicans orf19.3171 ORF ACH1 CAL0002388 PMID: 18689527|CGD_REF: CAL0119372 homozygous diploid, classical genetics null Not recorded utilization of carbon source: decreased ethanol C. albicans orf19.3171 ORF ACH1 CAL0002388 PMID: 18689527|CGD_REF: CAL0119372 homozygous diploid, classical genetics null Not recorded virulence: normal mouse intravenous infection C. albicans orf19.3174 ORF CDC24 CAL0002395 PMID: 15755921|CGD_REF: CAL0082335 heterozygous diploid, classical genetics overexpression BWP17 germ tube formation: abnormal germ tubes are longer than wild-type C. albicans orf19.3174 ORF CDC24 CAL0002395 PMID: 15755921|CGD_REF: CAL0082335 heterozygous diploid, classical genetics repressible BWP17 hyphal growth: abnormal solid serum-containing medium elongated buds, indicating that hyphal growth is induced but not maintained C. albicans orf19.3174 ORF CDC24 CAL0002395 PMID: 12582118|CGD_REF: CAL0080793 heterozygous diploid, classical genetics misexpression BWP17 hyphal growth: decreased liquid media plus serum severe decrease C. albicans orf19.3174 ORF CDC24 CAL0002395 PMID: 12582118|CGD_REF: CAL0080793 heterozygous diploid, classical genetics misexpression BWP17 hyphal growth: absent solid media, with or without serum C. albicans orf19.3174 ORF CDC24 CAL0002395 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.3174 ORF CDC24 CAL0002395 PMID: 12582118|CGD_REF: CAL0080793 heterozygous diploid, classical genetics null Not recorded viable wild-type growth rate C. albicans orf19.3174 ORF CDC24 CAL0002395 PMID: 15755921|CGD_REF: CAL0082335 heterozygous diploid, classical genetics overexpression Not recorded viable C. albicans orf19.3174 ORF CDC24 CAL0002395 PMID: 15755921|CGD_REF: CAL0082335 heterozygous diploid, classical genetics overexpression BWP17 invasive growth: normal C. albicans orf19.3174 ORF CDC24 CAL0002395 PMID: 12582118|CGD_REF: CAL0080793 heterozygous diploid, classical genetics repressible BWP17 inviable C. albicans orf19.3174 ORF CDC24 CAL0002395 PMID: 12582118|CGD_REF: CAL0080793 heterozygous diploid, classical genetics misexpression BWP17 virulence: absent mouse intravenous infection C. albicans orf19.3174 ORF CDC24 CAL0002395 PMID: 21135205|CGD_REF: CAL0139967 heterozygous diploid, competitive growth (large-scale identification of genes essential for virulence in mouse) repressible CAI-4 virulence: decreased mouse intravenous infection C. albicans orf19.3175 ORF CAL0002397 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.3176 ORF RIM21 CAL0002399 PMID: 19230847|CGD_REF: CAL0122428 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased lithium chloride solid YPD medium C. albicans orf19.3176 ORF RIM21 CAL0002399 PMID: 19230847|CGD_REF: CAL0122428 homozygous diploid, classical genetics null BWP17 hyphal growth: abnormal M199 medium, pH 7.5 C. albicans orf19.3176 ORF RIM21 CAL0002399 PMID: 12819929|CGD_REF: CAL0081778 homozygous diploid, classical genetics null Not recorded vegetative growth: decreased rate alkaline pH C. albicans orf19.3176 ORF RIM21 CAL0002399 PMID: 12819929|CGD_REF: CAL0081778 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.3176 ORF RIM21 CAL0002399 PMID: 19230847|CGD_REF: CAL0122428 homozygous diploid, classical genetics null Not recorded alkaline pH resistance: decreased solid SC medium at pH 10.0 C. albicans orf19.3176 ORF RIM21 CAL0002399 PMID: 22427429|CGD_REF: CAL0000156990 homozygous diploid, classical genetics null BWP17 protein/peptide modification: absent mutants don't process RIM8-HA RIM8-HA C. albicans orf19.3177 ORF CAL0002400 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.3177 ORF CAL0002400 PMID: 21135205|CGD_REF: CAL0139967 heterozygous diploid, large-scale survey (large-scale identification of genes essential for virulence in mouse) repressible CAI-4 virulence: absent mouse intravenous infection C. albicans orf19.3178 ORF CAL0002401 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.318 ORF CAL0004670 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.3181.1 ORF CAF0006977 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 invasive growth: decreased solid SLAD media C. albicans orf19.3182 ORF GIS2 CAL0002417 PMID: 20041210|CGD_REF: CAL0124764 homozygous diploid, systematic mutation set null SN152 resistance to chemicals: decreased flucytosine strongly sensitive C. albicans orf19.3182 ORF GIS2 CAL0002417 PMID: 20041210|CGD_REF: CAL0124764 homozygous diploid, systematic mutation set null SN152 acid pH resistance: decreased pH 2.0 severely sensitive C. albicans orf19.3182 ORF GIS2 CAL0002417 PMID: 20041210|CGD_REF: CAL0124764 homozygous diploid, systematic mutation set null SN152 cold sensitivity: increased reduced temperature (16 deg C, YEPD medium) strongly sensitive C. albicans orf19.3182 ORF GIS2 CAL0002417 PMID: 20041210|CGD_REF: CAL0124764 homozygous diploid, systematic mutation set null SN152 hyperosmotic stress resistance: decreased glucitol strongly sensitive C. albicans orf19.3182 ORF GIS2 CAL0002417 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.3182 ORF GIS2 CAL0002417 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.3182 ORF GIS2 CAL0002417 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.3182 ORF GIS2 CAL0002417 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.3187 ORF ZNC1 CAL0002425 PMID: 15964282|CGD_REF: CAL0114274 homozygous diploid, systematic mutation set (split-marker transposon insertion strategy to disrupt both alleles) null BWP17 viable C. albicans orf19.3187 ORF ZNC1 CAL0002425 PMID: 19463063|CGD_REF: CAL0123630 homozygous diploid, systematic mutation set (split-marker transposon insertion strategy to disrupt both alleles) null BWP17 viable C. albicans orf19.3187 ORF ZNC1 CAL0002425 PMID: 15590837|CGD_REF: CAL0082486 heterozygous diploid, classical genetics null Not recorded viable C. albicans orf19.3187 ORF ZNC1 CAL0002425 PMID: 15964282|CGD_REF: CAL0114274 homozygous diploid, systematic mutation set (split-marker transposon insertion strategy to disrupt both alleles) null BWP17 biofilm formation: normal C. albicans orf19.3187 ORF ZNC1 CAL0002425 PMID: 15590837|CGD_REF: CAL0082486 homozygous diploid, classical genetics null Not recorded inviable homozygous null mutant strain could not be recovered, suggesting that the gene is essential under the selection conditions C. albicans orf19.3187 ORF ZNC1 CAL0002425 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.3187 ORF ZNC1 CAL0002425 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.3187 ORF ZNC1 CAL0002425 PMID: 22359502|CGD_REF: CAL0000144048 homozygous diploid, classical genetics null BWP17 viable insertion mutant, independent BWP17 and SN152 deletion mutants also tested C. albicans orf19.3187 ORF ZNC1 CAL0002425 PMID: 22359502|CGD_REF: CAL0000144048 homozygous diploid, classical genetics null BWP17 adhesion: decreased insertion mutant, independent BWP17 and SN152 deletion mutants also tested C. albicans orf19.3187 ORF ZNC1 CAL0002425 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.3187 ORF ZNC1 CAL0002425 PMID: 19463063|CGD_REF: CAL0123630 homozygous diploid, systematic mutation set (split-marker transposon insertion strategy to disrupt both alleles) null BWP17 virulence: normal Toll mutant D. melanogaster invasive infection insect infection C. albicans orf19.3187 ORF ZNC1 CAL0002425 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.3188 ORF TAC1 CAL0002426 PMID: 15590837|CGD_REF: CAL0082486 homozygous diploid, classical genetics null Not recorded resistance to chemicals: normal flucytosine C. albicans orf19.3188 ORF TAC1 CAL0002426 PMID: 19089303|CGD_REF: CAL0122011 homozygous diploid, classical genetics unspecified Not recorded viable strain with laboratory-evolved fluconazole resistance is found to have acquired ERG3-D19E and TAC1-L47K, N977K changes; causality was not demonstrated between these mutations and the drug resistance phenotype C. albicans orf19.3188 ORF TAC1 CAL0002426 PMID: 15590837|CGD_REF: CAL0082486 heterozygous diploid, classical genetics null Not recorded viable C. albicans orf19.3188 ORF TAC1 CAL0002426 PMID: 15590837|CGD_REF: CAL0082486 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.3188 ORF TAC1 CAL0002426 PMID: 16452151|CGD_REF: CAL0115894 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.3188 ORF TAC1 CAL0002426 PMID: 20086148|CGD_REF: CAL0124781 homozygous diploid, classical genetics gain of function Other C. albicans RNA accumulation: increased constitutive high expression of CDR1 and CDR2 CDR2 mRNA C. albicans orf19.3188 ORF TAC1 CAL0002426 PMID: 20086148|CGD_REF: CAL0124781 heterozygous diploid, classical genetics null viable a N977D mutation is present in the heterozygous allele C. albicans orf19.3188 ORF TAC1 CAL0002426 PMID: 20086148|CGD_REF: CAL0124781 homozygous diploid, classical genetics null viable C. albicans orf19.3188 ORF TAC1 CAL0002426 PMID: 20086148|CGD_REF: CAL0124781 homozygous diploid, classical genetics null resistance to chemicals: decreased azoles C. albicans orf19.3188 ORF TAC1 CAL0002426 PMID: 20086148|CGD_REF: CAL0124781 homozygous diploid, classical genetics gain of function Other C. albicans RNA accumulation: increased constitutive high expression of CDR1 and CDR2 CDR1 mRNA C. albicans orf19.3188 ORF TAC1 CAL0002426 PMID: 15590837|CGD_REF: CAL0082486 heterozygous diploid, classical genetics activation TAC1-2 (derived from a clinical isolate) Not recorded resistance to chemicals: increased triazoles mutation causes increased CDR1 and CDR2 expression, which leads to azole resistance C. albicans orf19.3188 ORF TAC1 CAL0002426 PMID: 16452151|CGD_REF: CAL0115894 heterozygous diploid, classical genetics activation TAC1-5 (N977D mutation, contained in TAC1-5 and TAC1-7 alleles) Not recorded resistance to chemicals: increased fluconazole mutation also causes increased rhodamine G6 efflux; codominance/dosage effects observed C. albicans orf19.3188 ORF TAC1 CAL0002426 PMID: 16452151|CGD_REF: CAL0115894 heterozygous diploid, classical genetics activation TAC1-5 (N977D mutation, contained in TAC1-5 and TAC1-7 alleles) Not recorded resistance to chemicals: increased terbinafine mutation also causes increased rhodamine G6 efflux; codominance/dosage effects observed C. albicans orf19.3188 ORF TAC1 CAL0002426 PMID: 16452151|CGD_REF: CAL0115894 heterozygous diploid, classical genetics activation TAC1-5 (N977D mutation, contained in TAC1-5 and TAC1-7 alleles) Not recorded viable C. albicans orf19.3188 ORF TAC1 CAL0002426 PMID: 15590837|CGD_REF: CAL0082486 homozygous diploid, classical genetics null Not recorded resistance to chemicals: normal caspofungin C. albicans orf19.3188 ORF TAC1 CAL0002426 PMID: 15590837|CGD_REF: CAL0082486 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased fluphenazine C. albicans orf19.3188 ORF TAC1 CAL0002426 PMID: 15590837|CGD_REF: CAL0082486 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased terbinafine C. albicans orf19.3188 ORF TAC1 CAL0002426 PMID: 18363649|CGD_REF: CAL0118932 aneuploid, classical genetics activation Not recorded resistance to chemicals: increased fluconazole increased fluconazole resistance in aneuploid strains with multiplied hyperactive TAC1-1 allele C. albicans orf19.3188 ORF TAC1 CAL0002426 PMID: 15590837|CGD_REF: CAL0082486 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased fluconazole C. albicans orf19.3188 ORF TAC1 CAL0002426 PMID: 16452151|CGD_REF: CAL0115894 heterozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased fluconazole C. albicans orf19.3188 ORF TAC1 CAL0002426 PMID: 16452151|CGD_REF: CAL0115894 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased fluconazole C. albicans orf19.3188 ORF TAC1 CAL0002426 PMID: 22073120|CGD_REF: CAL0000143592 homozygous diploid, classical genetics null BWP17 viable C. albicans orf19.3188 ORF TAC1 CAL0002426 PMID: 22073120|CGD_REF: CAL0000143592 homozygous diploid, classical genetics null BWP17 oxidative stress resistance: decreased C. albicans orf19.3188 ORF TAC1 CAL0002426 PMID: 22073120|CGD_REF: CAL0000143592 homozygous diploid, classical genetics null BWP17 hyphal growth: decreased C. albicans orf19.3188 ORF TAC1 CAL0002426 PMID: 24243794|CGD_REF: CAL0000173702 homozygous diploid, classical genetics gain of function TAC1-5 SC5314 virulence: decreased mouse intravenous infection C. albicans orf19.3188 ORF TAC1 CAL0002426 PMID: 20876623|CGD_REF: CAL0126452 homozygous diploid, classical genetics gain of function TAC1(A736T, N977D, N972S, E461K, R673Q, H741Y, S108N, P276L, S290C, F973S, N740S and N740D) Other C. albicans resistance to chemicals: increased azoles C. albicans orf19.3190 ORF HAL9 CAL0002440 PMID: 14663094|CGD_REF: CAL0080633 homozygous diploid, systematic mutation set (homozygous insertion mutants generated with URA3-ARG4-URA3 (UAU1) cassette) null BWP17 viable C. albicans orf19.3190 ORF HAL9 CAL0002440 PMID: 15590837|CGD_REF: CAL0082486 heterozygous diploid, classical genetics null Not recorded viable C. albicans orf19.3190 ORF HAL9 CAL0002440 PMID: 15590837|CGD_REF: CAL0082486 homozygous diploid, classical genetics null Not recorded inviable homozygous null mutant strain could not be recovered, suggesting that the gene is essential under the selection conditions C. albicans orf19.3190 ORF HAL9 CAL0002440 PMID: 22073120|CGD_REF: CAL0000143592 homozygous diploid, classical genetics null BWP17 viable C. albicans orf19.3190 ORF HAL9 CAL0002440 PMID: 22073120|CGD_REF: CAL0000143592 homozygous diploid, classical genetics null BWP17 invasive growth: increased increased agar invasion C. albicans orf19.3190 ORF HAL9 CAL0002440 PMID: 22073120|CGD_REF: CAL0000143592 homozygous diploid, classical genetics null BWP17 viable C. albicans orf19.3190 ORF HAL9 CAL0002440 PMID: 22073120|CGD_REF: CAL0000143592 homozygous diploid, classical genetics null BWP17 colony appearance: abnormal decreased colony wrinkling C. albicans orf19.3192 ORF STI1 CAL0002444 PMID: 19115836|CGD_REF: CAL0122036 heterozygous diploid, competitive growth (haploinsufficient phenotype assay, barcode deletion set) null SC5314 resistance to chemicals: decreased radicicol C. albicans orf19.3192 ORF STI1 CAL0002444 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 invasive growth: decreased solid SLAD media C. albicans orf19.3193 ORF FCR3 CAL0002445 PMID: 15964282|CGD_REF: CAL0114274 homozygous diploid, systematic mutation set (split-marker transposon insertion strategy to disrupt both alleles) null BWP17 viable C. albicans orf19.3193 ORF FCR3 CAL0002445 PMID: 15964282|CGD_REF: CAL0114274 homozygous diploid, systematic mutation set (split-marker transposon insertion strategy to disrupt both alleles) null BWP17 biofilm formation: normal C. albicans orf19.3193 ORF FCR3 CAL0002445 PMID: 22359502|CGD_REF: CAL0000144048 homozygous diploid, classical genetics null BWP17 viable insertion mutant, independent SN152 deletion mutant strain also tested C. albicans orf19.3193 ORF FCR3 CAL0002445 PMID: 22359502|CGD_REF: CAL0000144048 homozygous diploid, classical genetics null BWP17 adhesion: decreased insertion mutant, independent SN152 deletion mutant strain also tested C. albicans orf19.3196 ORF CAL0002450 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient SC medium C. albicans orf19.3197 ORF PAP1 CAL0002451 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.3197 ORF PAP1 CAL0002451 PMID: 22253594|CGD_REF: CAL0000143870 heterozygous diploid, classical genetics null Other C. albicans biofilm formation: decreased C. albicans orf19.3197 ORF PAP1 CAL0002451 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient SLAD medium C. albicans orf19.3197 ORF PAP1 CAL0002451 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 invasive growth: decreased solid SLAD media C. albicans orf19.3197 ORF PAP1 CAL0002451 PMID: 21135205|CGD_REF: CAL0139967 heterozygous diploid, large-scale survey (large-scale identification of genes essential for virulence in mouse) repressible CAI-4 virulence: absent mouse intravenous infection C. albicans orf19.3198 ORF OBPA CAL0002452 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.3198 ORF OBPA CAL0002452 PMID: 22253594|CGD_REF: CAL0000143870 heterozygous diploid, classical genetics null obpa/obpalpha Other C. albicans virulence: decreased mouse intravenous infection C. albicans orf19.3198 ORF OBPA CAL0002452 PMID: 22253594|CGD_REF: CAL0000143870 heterozygous diploid, classical genetics null Other C. albicans biofilm formation: decreased C. albicans orf19.3199 ORF PIKA CAL0002453 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.3199 ORF PIKA CAL0002453 PMID: 22253594|CGD_REF: CAL0000143870 heterozygous diploid, classical genetics null Other C. albicans biofilm formation: decreased C. albicans orf19.320 ORF CAL0004696 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.320 ORF CAL0004696 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 invasive growth: decreased solid SLAD media C. albicans orf19.3200 ORF MTLA2 CAL0003184 PMID: 14622594|CGD_REF: CAL0081573 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.3200 ORF MTLA2 CAL0003184 PMID: 16087738|CGD_REF: CAL0114510 homozygous diploid, classical genetics misexpression WO-1 mating response: abnormal expression in opaque MTLalpha homozygote WO-1 (but not in MTLa/alpha heterozygote or MTLa strain lacking MTLalpha) cells induces formation of mating projections (shmoos) C. albicans orf19.3201 ORF MTLA1 CAL0003187 PMID: 17555440|CGD_REF: CAL0117935 homozygous diploid, classical genetics null Not recorded viable strain is an a/alpha heterozygote C. albicans orf19.3201 ORF MTLA1 CAL0003187 PMID: 14622594|CGD_REF: CAL0081573 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.3201 ORF MTLA1 CAL0003187 PMID: 17071565|CGD_REF: CAL0116853 heterozygous diploid, classical genetics null Not recorded chlamydospore formation: normal mtla1 mutation in MTLa/MTLalpha background C. albicans orf19.3201 ORF MTLA1 CAL0003187 PMID: 16087738|CGD_REF: CAL0114510 homozygous diploid, classical genetics misexpression WO-1 phenotypic switching: abnormal expression in opaque MTLalpha homozygote cells induces opaque-to-white switching C. albicans orf19.3201 ORF MTLA1 CAL0003187 PMID: 14622594|CGD_REF: CAL0081573 homozygous diploid, classical genetics null Not recorded phenotypic switching: abnormal repression of white-to-opaque switching is lost C. albicans orf19.3201 ORF MTLA1 CAL0003187 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: decreased growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.3201 ORF MTLA1 CAL0003187 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.3201 ORF MTLA1 CAL0003187 PMID: 17555440|CGD_REF: CAL0117935 homozygous diploid, classical genetics null Not recorded virulence: decreased variability observed between different strain backgrounds mouse intravenous infection C. albicans orf19.3201 ORF MTLA1 CAL0003187 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.3201 ORF MTLA1 CAL0003187 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.3202 ORF CAL0003188 PMID: 14663094|CGD_REF: CAL0080633 homozygous diploid, systematic mutation set (homozygous insertion mutants generated with URA3-ARG4-URA3 (UAU1) cassette) null BWP17 viable C. albicans orf19.3203 ORF RCY1 CAL0003190 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.3203 ORF RCY1 CAL0003190 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.3203 ORF RCY1 CAL0003190 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: abnormal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.3203 ORF RCY1 CAL0003190 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: decreased rate liquid synthetic complete medium C. albicans orf19.3203 ORF RCY1 CAL0003190 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.3204 ORF CAL0003193 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.3205 ORF MPRL36 CAL0003196 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.3206 ORF CCT7 CAL0003198 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.3207 ORF CCN1 CAL0003199 PMID: 10330142|CGD_REF: CAL0081038 homozygous diploid, classical genetics null Not recorded hyphal growth: decreased solid serum-containing or liquid Lee mannitol media hyphal growth is initiated but not maintained C. albicans orf19.3207 ORF CCN1 CAL0003199 PMID: 17765684|CGD_REF: CAL0118343 homozygous diploid, classical genetics null BWP17 hyphal growth: absent unable to maintain polarized tip growth C. albicans orf19.3207 ORF CCN1 CAL0003199 PMID: 10330142|CGD_REF: CAL0081038 heterozygous diploid, classical genetics null Not recorded hyphal growth: decreased solid or liquid Lee mannitol media C. albicans orf19.3207 ORF CCN1 CAL0003199 PMID: 10330142|CGD_REF: CAL0081038 heterozygous diploid, classical genetics null Not recorded vegetative growth: decreased rate C. albicans orf19.3207 ORF CCN1 CAL0003199 PMID: 10330142|CGD_REF: CAL0081038 homozygous diploid, classical genetics null Not recorded vegetative growth: decreased rate C. albicans orf19.3207 ORF CCN1 CAL0003199 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.3207 ORF CCN1 CAL0003199 PMID: 10330142|CGD_REF: CAL0081038 heterozygous diploid, classical genetics null Not recorded viable C. albicans orf19.3207 ORF CCN1 CAL0003199 PMID: 10330142|CGD_REF: CAL0081038 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.3207 ORF CCN1 CAL0003199 PMID: 17765684|CGD_REF: CAL0118343 heterozygous diploid, classical genetics null BWP17 viable C. albicans orf19.3207 ORF CCN1 CAL0003199 PMID: 17765684|CGD_REF: CAL0118343 homozygous diploid, classical genetics null BWP17 viable C. albicans orf19.3207 ORF CCN1 CAL0003199 PMID: 17765684|CGD_REF: CAL0118343 homozygous diploid, classical genetics null Not recorded bud neck morphology: abnormal neck is elongated, and cytokinesis is misplaced in 30% of the cells C. albicans orf19.3207 ORF CCN1 CAL0003199 PMID: 10330142|CGD_REF: CAL0081038 homozygous diploid, classical genetics null Not recorded invasive growth: absent solid Lee mannitol media C. albicans orf19.3207 ORF CCN1 CAL0003199 PMID: 10330142|CGD_REF: CAL0081038 homozygous diploid, classical genetics null Not recorded mitotic cell cycle: decreased rate slow cell cycle progression and enlarged cells C. albicans orf19.3207 ORF CCN1 CAL0003199 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, competitive growth (haploinsufficient phenotype assay, barcode deletion set) null SC5314 resistance to chemicals: decreased amphotericin B C. albicans orf19.3207 ORF CCN1 CAL0003199 PMID: 10330142|CGD_REF: CAL0081038 homozygous diploid, classical genetics null Not recorded filamentous growth: decreased solid Lee mannitol media colonies do not exhibit radial filaments C. albicans orf19.3207 ORF CCN1 CAL0003199 PMID: 10330142|CGD_REF: CAL0081038 heterozygous diploid, classical genetics null Not recorded filamentous growth: decreased solid Lee mannitol media colonies exhibit fewer radial filaments C. albicans orf19.3207 ORF CCN1 CAL0003199 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.3207 ORF CCN1 CAL0003199 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: abnormal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.3207 ORF CCN1 CAL0003199 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.3207 ORF CCN1 CAL0003199 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.3208 ORF DAL52 CAL0003200 PMID: 14663094|CGD_REF: CAL0080633 homozygous diploid, systematic mutation set (homozygous insertion mutants generated with URA3-ARG4-URA3 (UAU1) cassette) null BWP17 viable C. albicans orf19.3209 ORF FGR42 CAL0003201 PMID: 12773383|CGD_REF: CAL0087974 heterozygous diploid, classical genetics (haploinsufficient phenotype assay) null CAI-4 viable heterozygous transposon insertion C. albicans orf19.321 ORF CAL0004697 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.3211 ORF RCF3 CAL0003213 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.3211 ORF RCF3 CAL0003213 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 invasive growth: decreased solid SLAD media C. albicans orf19.3212 ORF MID1 CAL0003216 PMID: 19755168|CGD_REF: CAL0124242 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased lithium chloride C. albicans orf19.3212 ORF MID1 CAL0003216 PMID: 18765290|CGD_REF: CAL0119430 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased Calcofluor White C. albicans orf19.3212 ORF MID1 CAL0003216 PMID: 19755168|CGD_REF: CAL0124242 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased sodium dodecyl sulfate C. albicans orf19.3212 ORF MID1 CAL0003216 PMID: 17275302|CGD_REF: CAL0117325 homozygous diploid, classical genetics null CAI-4 hyphal growth: abnormal abnormal directional growth of hyphae C. albicans orf19.3212 ORF MID1 CAL0003216 PMID: 19154328|CGD_REF: CAL0122236 homozygous diploid, classical genetics null Other C. albicans hyphal growth: abnormal semisolid substrate decreased hyphal tip oscillation C. albicans orf19.3212 ORF MID1 CAL0003216 PMID: 19154328|CGD_REF: CAL0122236 homozygous diploid, classical genetics null Other C. albicans hyphal growth: abnormal semisolid substrate decreased oscillatory amplitude of hyphal tip oscillation C. albicans orf19.3212 ORF MID1 CAL0003216 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.3212 ORF MID1 CAL0003216 PMID: 17275302|CGD_REF: CAL0117325 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.3212 ORF MID1 CAL0003216 PMID: 18765290|CGD_REF: CAL0119430 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.3212 ORF MID1 CAL0003216 PMID: 22886468|CGD_REF: CAL0000157678 homozygous diploid, classical genetics null BWP17 hyphal growth: decreased C. albicans orf19.3212 ORF MID1 CAL0003216 PMID: 22886468|CGD_REF: CAL0000157678 homozygous diploid, classical genetics null BWP17 invasive growth: decreased C. albicans orf19.3212 ORF MID1 CAL0003216 PMID: 22886468|CGD_REF: CAL0000157678 homozygous diploid, classical genetics null BWP17 oxidative stress resistance: decreased menadione C. albicans orf19.3212 ORF MID1 CAL0003216 PMID: 22886468|CGD_REF: CAL0000157678 homozygous diploid, classical genetics null BWP17 virulence: decreased mouse intravenous infection C. albicans orf19.3212 ORF MID1 CAL0003216 PMID: 18765290|CGD_REF: CAL0119430 homozygous diploid, classical genetics null Not recorded cell wall morphology: abnormal decreased thickness C. albicans orf19.3212 ORF MID1 CAL0003216 PMID: 18765290|CGD_REF: CAL0119430 homozygous diploid, classical genetics null Not recorded chitin deposition: decreased C. albicans orf19.3212 ORF MID1 CAL0003216 PMID: 17275302|CGD_REF: CAL0117325 homozygous diploid, classical genetics null Not recorded chemical compound accumulation: abnormal calcium C. albicans orf19.3212 ORF MID1 CAL0003216 PMID: 18765290|CGD_REF: CAL0119430 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased caspofungin C. albicans orf19.3212 ORF MID1 CAL0003216 PMID: 21457451|CGD_REF: CAL0141864 homozygous diploid, classical genetics null BWP17 viable C. albicans orf19.3212 ORF MID1 CAL0003216 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: decreased growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.3212 ORF MID1 CAL0003216 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.3212 ORF MID1 CAL0003216 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.3212 ORF MID1 CAL0003216 PMID: 20865172|CGD_REF: CAL0126252 homozygous diploid, classical genetics null SN95 resistance to chemicals: decreased fluconazole C. albicans orf19.3212 ORF MID1 CAL0003216 PMID: 20865172|CGD_REF: CAL0126252 homozygous diploid, classical genetics null SN95 resistance to chemicals: decreased fenpropimorph C. albicans orf19.3212 ORF MID1 CAL0003216 PMID: 20865172|CGD_REF: CAL0126252 homozygous diploid, classical genetics null SN95 resistance to chemicals: decreased terbinafine C. albicans orf19.3212 ORF MID1 CAL0003216 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.3215 ORF CAL0003225 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.3218 ORF CAL0003229 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.3218 ORF CAL0003229 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 invasive growth: decreased solid SLAD media C. albicans orf19.3219 ORF CAL0003230 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.3222 ORF CAL0003250 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.3225 ORF CWH43 CAL0003256 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.3226 ORF CAL0003259 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.3226 ORF CAL0003259 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.3226 ORF CAL0003259 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.3226 ORF CAL0003259 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.3226 ORF CAL0003259 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.3227 ORF FTH2 CAL0003260 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.3228 ORF CAL0003261 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.3229 ORF CAL0003262 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient YNB medium C. albicans orf19.3229 ORF CAL0003262 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient SLAD medium C. albicans orf19.3230 ORF BOI2 CAL0003275 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.3230 ORF BOI2 CAL0003275 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, competitive growth (haploinsufficient phenotype assay, barcode deletion set) null SC5314 resistance to chemicals: decreased ergosterol analogs (ECC69 and/or ECC1384) C. albicans orf19.3230 ORF BOI2 CAL0003275 PMID: 20402797|CGD_REF: CAL0125391 homozygous diploid, classical genetics null Other C. albicans vacuolar distribution: abnormal large central vacuole absent in germ tubes C. albicans orf19.3230 ORF BOI2 CAL0003275 PMID: 20402797|CGD_REF: CAL0125391 homozygous diploid, classical genetics null Other C. albicans viable C. albicans orf19.3231 ORF CDC27 CAL0003279 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.3232 ORF CAL0003283 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.3232 ORF CAL0003283 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, competitive growth (haploinsufficient phenotype assay, barcode deletion set) null SC5314 resistance to chemicals: decreased ergosterol analogs (ECC69 and/or ECC1384) C. albicans orf19.3233 ORF HSE1 CAL0003285 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.3233 ORF HSE1 CAL0003285 PMID: 20402797|CGD_REF: CAL0125391 homozygous diploid, classical genetics null Other C. albicans viable C. albicans orf19.3234 ORF OYE22 CAL0003287 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.3234.1 ORF SFT1 CAF0006978 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.3237 ORF CAL0003293 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.3237 ORF CAL0003293 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.3237 ORF CAL0003293 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.3237 ORF CAL0003293 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.3237 ORF CAL0003293 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.3240 ORF ERG27 CAL0003306 PMID: 15552648|CGD_REF: CAL0082139 heterozygous diploid, classical genetics repressible Not recorded vegetative growth: decreased rate strain grows poorly and exhibits a sterol profile like that of an S. cerevisiae erg27 mutant C. albicans orf19.3240 ORF ERG27 CAL0003306 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.3240 ORF ERG27 CAL0003306 PMID: 15552648|CGD_REF: CAL0082139 heterozygous diploid, classical genetics null Not recorded viable C. albicans orf19.3240 ORF ERG27 CAL0003306 PMID: 16607011|CGD_REF: CAL0115846 heterozygous diploid, classical genetics null Not recorded viable C. albicans orf19.3240 ORF ERG27 CAL0003306 PMID: 15552648|CGD_REF: CAL0082139 homozygous diploid, classical genetics null Not recorded inviable homozygous null mutant strain could not be recovered, suggesting that the gene is essential under the selection conditions C. albicans orf19.3240 ORF ERG27 CAL0003306 PMID: 16607011|CGD_REF: CAL0115846 homozygous diploid, classical genetics null SC5314 inviable homozygous null mutant strain could not be recovered, suggesting that the gene is essential under the selection conditions C. albicans orf19.3240 ORF ERG27 CAL0003306 PMID: 15893902|CGD_REF: CAL0114689 heterozygous diploid, classical genetics repressible Not recorded inviable not rescued by various exogenous sources of sterol, indicating lack of uptake C. albicans orf19.3240 ORF ERG27 CAL0003306 PMID: 16607011|CGD_REF: CAL0115846 heterozygous diploid, classical genetics repressible SC5314 inviable C. albicans orf19.3240 ORF ERG27 CAL0003306 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, competitive growth (haploinsufficient phenotype assay, barcode deletion set) null SC5314 resistance to chemicals: decreased radicicol C. albicans orf19.3240 ORF ERG27 CAL0003306 PMID: 19115836|CGD_REF: CAL0122036 heterozygous diploid, competitive growth (haploinsufficient phenotype assay, barcode deletion set) null SC5314 resistance to chemicals: decreased radicicol C. albicans orf19.3240 ORF ERG27 CAL0003306 PMID: 21135205|CGD_REF: CAL0139967 heterozygous diploid, large-scale survey (large-scale identification of genes essential for virulence in mouse) repressible CAI-4 virulence: absent mouse intravenous infection C. albicans orf19.3241 ORF CAL0003309 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.3242 ORF CAL0003312 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.3243 ORF SRP54 CAL0003314 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.3247 ORF CAL0003321 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.3247 ORF CAL0003321 PMID: 12524333|CGD_REF: CAL0080691 homozygous diploid, systematic mutation set (homozygous insertion mutants generated with URA3-ARG4-URA3 (UAU1) cassette) null BWP17 inviable homozygous null mutant strain could not be recovered, suggesting that the gene is essential under the selection conditions C. albicans orf19.3249 ORF LAG1 CAL0003323 PMID: 22211636|CGD_REF: CAL0000143845 homozygous diploid, classical genetics null lag1::dpl200/lag1::dpl200 CAI-4 viable C. albicans orf19.3249 ORF LAG1 CAL0003323 PMID: 22211636|CGD_REF: CAL0000143845 homozygous diploid, classical genetics null lag1::dpl200/lag1::dpl200 CAI-4 hyphal growth: absent C. albicans orf19.325 ORF CAL0004705 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.325 ORF CAL0004705 PMID: 19623926|CGD_REF: CAL0124054 heterozygous diploid, competitive growth (haploinsufficient phenotype assay, barcode deletion set) null SC5314 resistance to chemicals: decreased cordycepin C. albicans orf19.325 ORF CAL0004705 PMID: 19623926|CGD_REF: CAL0124054 heterozygous diploid, competitive growth (haploinsufficient phenotype assay, barcode deletion set) null SC5314 resistance to chemicals: decreased parnafungin C. albicans orf19.325 ORF CAL0004705 PMID: 21135205|CGD_REF: CAL0139967 heterozygous diploid, large-scale survey (large-scale identification of genes essential for virulence in mouse) repressible CAI-4 virulence: absent mouse intravenous infection C. albicans orf19.3250 ORF CAL0003333 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.3251 ORF ARC19 CAL0003336 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.3251 ORF ARC19 CAL0003336 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, competitive growth (haploinsufficient phenotype assay, barcode deletion set) null SC5314 resistance to chemicals: decreased cytochalasin D C. albicans orf19.3252 ORF DAL81 CAL0003338 PMID: 22359502|CGD_REF: CAL0000144048 homozygous diploid, classical genetics null BWP17 viable insertion mutant, independent SN152 deletion mutant strain also tested C. albicans orf19.3252 ORF DAL81 CAL0003338 PMID: 22359502|CGD_REF: CAL0000144048 homozygous diploid, classical genetics null BWP17 adhesion: decreased insertion mutant, independent SN152 deletion mutant strain also tested C. albicans orf19.3254 ORF CAL0003341 PMID: 14663094|CGD_REF: CAL0080633 homozygous diploid, systematic mutation set (homozygous insertion mutants generated with URA3-ARG4-URA3 (UAU1) cassette) null BWP17 viable C. albicans orf19.3255 ORF TEN1 CAL0003343 PMID: 20008938|CGD_REF: CAL0124723 homozygous diploid, classical genetics null BWP17 viable C. albicans orf19.3255 ORF TEN1 CAL0003343 PMID: 20008938|CGD_REF: CAL0124723 homozygous diploid, classical genetics null BWP17 vegetative growth: decreased rate C. albicans orf19.3255 ORF TEN1 CAL0003343 PMID: 20008938|CGD_REF: CAL0124723 homozygous diploid, classical genetics null BWP17 filamentous growth: increased increased abundance of filamentous cells in liquid cultures C. albicans orf19.3255 ORF TEN1 CAL0003343 PMID: 20008938|CGD_REF: CAL0124723 homozygous diploid, classical genetics null BWP17 telomere length: increased extremely long and heterogeneous telomeres C. albicans orf19.3256 ORF SLN1 CAL0003344 PMID: 15470110|CGD_REF: CAL0082464 homozygous diploid, classical genetics null Not recorded germ tube formation: normal serum-containing medium C. albicans orf19.3256 ORF SLN1 CAL0003344 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.3256 ORF SLN1 CAL0003344 PMID: 14507372|CGD_REF: CAL0088818 heterozygous diploid, large-scale survey (large-scale identification of essential genes by gene replacement and conditional expression (GRACE) method) repressible CAI-4 viable one allele is deleted and the other is placed under repressible Tet promoter C. albicans orf19.3256 ORF SLN1 CAL0003344 PMID: 9493379|CGD_REF: CAL0081391 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.3256 ORF SLN1 CAL0003344 PMID: 10572127|CGD_REF: CAL0081384 homozygous diploid, classical genetics null sln1::hisG-URA3-hisG/sln1::hisG-URA3-hisG CAI-4 hyphal growth: decreased solid YEPD plus serum C. albicans orf19.3256 ORF SLN1 CAL0003344 PMID: 10572127|CGD_REF: CAL0081384 homozygous diploid, classical genetics null sln1::hisG-URA3-hisG/sln1::hisG-URA3-hisG CAI-4 viable C. albicans orf19.3256 ORF SLN1 CAL0003344 PMID: 10572127|CGD_REF: CAL0081384 homozygous diploid, classical genetics null sln1::hisG-URA3-hisG/sln1::hisG-URA3-hisG CAI-4 virulence: decreased mouse intravenous infection C. albicans orf19.3256 ORF SLN1 CAL0003344 PMID: 9493379|CGD_REF: CAL0081391 homozygous diploid, classical genetics null Not recorded osmotic stress resistance: decreased C. albicans orf19.3259 ORF CAL0003345 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.3264 ORF CCE1 CAL0003364 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 invasive growth: decreased solid SLAD media C. albicans orf19.3265 ORF TRM1 CAL0003366 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.3267 ORF CAL0003368 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.3267 ORF CAL0003368 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient SC medium C. albicans orf19.3267 ORF CAL0003368 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 invasive growth: decreased solid SLAD media C. albicans orf19.3268 ORF TMA19 CAL0003369 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 invasive growth: decreased solid SLAD media C. albicans orf19.3269 ORF GSL2 CAL0003370 PMID: 9209021|CGD_REF: CAL0081298 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.3273 ORF CAL0003387 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.3276 ORF PWP2 CAL0003392 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.3277 ORF CAL0003393 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 invasive growth: decreased solid SLAD media C. albicans orf19.3279 ORF HYR4 CAL0003395 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.3279 ORF HYR4 CAL0003395 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.3279 ORF HYR4 CAL0003395 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.3279 ORF HYR4 CAL0003395 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.3279 ORF HYR4 CAL0003395 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 invasive growth: decreased solid SLAD media C. albicans orf19.328 ORF NPR2 CAL0004714 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: decreased growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.328 ORF NPR2 CAL0004714 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: abnormal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.328 ORF NPR2 CAL0004714 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: decreased rate liquid synthetic complete medium C. albicans orf19.328 ORF NPR2 CAL0004714 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.3281 ORF CAL0003411 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.3282 ORF BMT3 CAL0003413 PMID: 18234669|CGD_REF: CAL0119018 homozygous diploid, classical genetics null Not recorded resistance to chemicals: normal Calcofluor White C. albicans orf19.3282 ORF BMT3 CAL0003413 PMID: 18234669|CGD_REF: CAL0119018 homozygous diploid, classical genetics null Not recorded resistance to chemicals: normal sodium dodecyl sulfate C. albicans orf19.3282 ORF BMT3 CAL0003413 PMID: 18234669|CGD_REF: CAL0119018 homozygous diploid, classical genetics null BWP17 hyphal growth: normal serum-containing medium C. albicans orf19.3282 ORF BMT3 CAL0003413 PMID: 18234669|CGD_REF: CAL0119018 homozygous diploid, classical genetics null Not recorded viable rich medium wild-type growth rate C. albicans orf19.3282 ORF BMT3 CAL0003413 PMID: 18234669|CGD_REF: CAL0119018 homozygous diploid, classical genetics null Not recorded cell wall morphology: abnormal strongly decreased beta-mannosylation of both acid-stable and acid-labile fractions of phosphopeptidomannan C. albicans orf19.3282 ORF BMT3 CAL0003413 PMID: 18234669|CGD_REF: CAL0119018 homozygous diploid, classical genetics null Not recorded chlamydospore formation: normal RAT medium C. albicans orf19.3282 ORF BMT3 CAL0003413 PMID: 18234669|CGD_REF: CAL0119018 homozygous diploid, classical genetics null Not recorded ionic stress resistance: normal sodium chloride C. albicans orf19.3282 ORF BMT3 CAL0003413 PMID: 18234669|CGD_REF: CAL0119018 homozygous diploid, classical genetics null Not recorded resistance to chemicals: normal calcium dichloride C. albicans orf19.3283 ORF CAL0003415 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: decreased growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.3283 ORF CAL0003415 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.3283 ORF CAL0003415 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.3283 ORF CAL0003415 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.329 ORF CAL0004717 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.3290 ORF CAL0003434 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.3290 ORF CAL0003434 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: decreased growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.3290 ORF CAL0003434 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.3290 ORF CAL0003434 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.3290 ORF CAL0003434 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.3291 ORF HMT1 CAL0003436 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.3291 ORF HMT1 CAL0003436 PMID: 17483287|CGD_REF: CAL0118089 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.3292 ORF CAL0003438 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.3293 ORF CAL0003440 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.3293 ORF CAL0003440 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient YPD medium C. albicans orf19.3293 ORF CAL0003440 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient SC medium C. albicans orf19.3293 ORF CAL0003440 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient YNB medium C. albicans orf19.3293 ORF CAL0003440 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient SLAD medium C. albicans orf19.3294 ORF MBF1 CAL0003442 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.3298 ORF CCH1 CAL0003447 PMID: 19755168|CGD_REF: CAL0124242 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased lithium chloride C. albicans orf19.3298 ORF CCH1 CAL0003447 PMID: 19755168|CGD_REF: CAL0124242 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased sodium dodecyl sulfate C. albicans orf19.3298 ORF CCH1 CAL0003447 PMID: 17275302|CGD_REF: CAL0117325 homozygous diploid, classical genetics null CAI-4 hyphal growth: abnormal abnormal directional growth of hyphae C. albicans orf19.3298 ORF CCH1 CAL0003447 PMID: 19154328|CGD_REF: CAL0122236 homozygous diploid, classical genetics null Other C. albicans hyphal growth: abnormal semisolid substrate decreased hyphal tip oscillation C. albicans orf19.3298 ORF CCH1 CAL0003447 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.3298 ORF CCH1 CAL0003447 PMID: 17275302|CGD_REF: CAL0117325 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.3298 ORF CCH1 CAL0003447 PMID: 22886468|CGD_REF: CAL0000157678 homozygous diploid, classical genetics null BWP17 invasive growth: decreased C. albicans orf19.3298 ORF CCH1 CAL0003447 PMID: 22886468|CGD_REF: CAL0000157678 homozygous diploid, classical genetics null BWP17 hyphal growth: decreased C. albicans orf19.3298 ORF CCH1 CAL0003447 PMID: 22886468|CGD_REF: CAL0000157678 homozygous diploid, classical genetics null BWP17 oxidative stress resistance: decreased hydrogen peroxide C. albicans orf19.3298 ORF CCH1 CAL0003447 PMID: 22886468|CGD_REF: CAL0000157678 homozygous diploid, classical genetics null BWP17 oxidative stress resistance: decreased menadione C. albicans orf19.3298 ORF CCH1 CAL0003447 PMID: 22886468|CGD_REF: CAL0000157678 homozygous diploid, classical genetics null BWP17 virulence: decreased mouse intravenous infection C. albicans orf19.3298 ORF CCH1 CAL0003447 PMID: 17275302|CGD_REF: CAL0117325 homozygous diploid, classical genetics null Not recorded chemical compound accumulation: abnormal calcium C. albicans orf19.3298 ORF CCH1 CAL0003447 PMID: 21457451|CGD_REF: CAL0141864 homozygous diploid, classical genetics null BWP17 viable C. albicans orf19.3298 ORF CCH1 CAL0003447 PMID: 20865172|CGD_REF: CAL0126252 homozygous diploid, classical genetics null SN95 resistance to chemicals: decreased fluconazole C. albicans orf19.3298 ORF CCH1 CAL0003447 PMID: 20865172|CGD_REF: CAL0126252 homozygous diploid, classical genetics null SN95 resistance to chemicals: decreased fenpropimorph C. albicans orf19.3298 ORF CCH1 CAL0003447 PMID: 20865172|CGD_REF: CAL0126252 homozygous diploid, classical genetics null SN95 resistance to chemicals: decreased terbinafine C. albicans orf19.3298 ORF CCH1 CAL0003447 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient YPD medium C. albicans orf19.3298 ORF CCH1 CAL0003447 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient SC medium C. albicans orf19.3298 ORF CCH1 CAL0003447 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient SLAD medium C. albicans orf19.330.1 ORF RUB1 CAF0006894 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.330.1 ORF RUB1 CAF0006894 PMID: 22080453|CGD_REF: CAL0000143626 homozygous diploid, classical genetics null Other C. albicans viable C. albicans orf19.330.1 ORF RUB1 CAF0006894 PMID: 22080453|CGD_REF: CAL0000143626 homozygous diploid, classical genetics null Other C. albicans cell shape: abnormal elongated cells C. albicans orf19.330.1 ORF RUB1 CAF0006894 PMID: 22080453|CGD_REF: CAL0000143626 homozygous diploid, classical genetics null Other C. albicans vegetative growth: decreased rate C. albicans orf19.3300 ORF ZPR1 CAL0004036 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.3300 ORF ZPR1 CAL0004036 PMID: 15964282|CGD_REF: CAL0114274 homozygous diploid, systematic mutation set (split-marker transposon insertion strategy to disrupt both alleles) null BWP17 viable C. albicans orf19.3300 ORF ZPR1 CAL0004036 PMID: 15964282|CGD_REF: CAL0114274 homozygous diploid, systematic mutation set (split-marker transposon insertion strategy to disrupt both alleles) null BWP17 biofilm formation: normal C. albicans orf19.3301 ORF CAL0004039 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.3302 ORF CAL0004041 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.3303 ORF CAL0004043 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.3304 ORF CAL0004045 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.3304 ORF CAL0004045 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 invasive growth: decreased solid SLAD media C. albicans orf19.3305 ORF ZCF17 CAL0004047 PMID: 17555439|CGD_REF: CAL0117968 homozygous diploid, classical genetics null Not recorded survival rate in stationary phase: decreased C. albicans orf19.3305 ORF ZCF17 CAL0004047 PMID: 15964282|CGD_REF: CAL0114274 homozygous diploid, systematic mutation set (split-marker transposon insertion strategy to disrupt both alleles) null BWP17 viable C. albicans orf19.3305 ORF ZCF17 CAL0004047 PMID: 15964282|CGD_REF: CAL0114274 homozygous diploid, systematic mutation set (split-marker transposon insertion strategy to disrupt both alleles) null BWP17 biofilm formation: normal C. albicans orf19.3305 ORF ZCF17 CAL0004047 PMID: 22073120|CGD_REF: CAL0000143592 homozygous diploid, classical genetics null BWP17 viable C. albicans orf19.3305 ORF ZCF17 CAL0004047 PMID: 22073120|CGD_REF: CAL0000143592 homozygous diploid, classical genetics null BWP17 hyphal growth: increased C. albicans orf19.3305 ORF ZCF17 CAL0004047 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 invasive growth: decreased solid SLAD media C. albicans orf19.3307 ORF CAL0004051 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.3308 ORF STB5 CAL0004052 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.3308 ORF STB5 CAL0004052 PMID: 15964282|CGD_REF: CAL0114274 homozygous diploid, systematic mutation set (split-marker transposon insertion strategy to disrupt both alleles) null BWP17 viable C. albicans orf19.3308 ORF STB5 CAL0004052 PMID: 19463063|CGD_REF: CAL0123630 homozygous diploid, systematic mutation set (split-marker transposon insertion strategy to disrupt both alleles) null BWP17 viable C. albicans orf19.3308 ORF STB5 CAL0004052 PMID: 15964282|CGD_REF: CAL0114274 homozygous diploid, systematic mutation set (split-marker transposon insertion strategy to disrupt both alleles) null BWP17 biofilm formation: normal C. albicans orf19.3308 ORF STB5 CAL0004052 PMID: 22073120|CGD_REF: CAL0000143592 homozygous diploid, classical genetics null BWP17 viable C. albicans orf19.3308 ORF STB5 CAL0004052 PMID: 22073120|CGD_REF: CAL0000143592 homozygous diploid, classical genetics null BWP17 colony appearance: abnormal increased colony wrinkling C. albicans orf19.3308 ORF STB5 CAL0004052 PMID: 19463063|CGD_REF: CAL0123630 homozygous diploid, systematic mutation set (split-marker transposon insertion strategy to disrupt both alleles) null BWP17 virulence: normal Toll mutant D. melanogaster invasive infection insect infection C. albicans orf19.331 ORF CAL0004742 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.3311 ORF IFD3 CAL0004065 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.3311 ORF IFD3 CAL0004065 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.3311 ORF IFD3 CAL0004065 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.3311 ORF IFD3 CAL0004065 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.3311 ORF IFD3 CAL0004065 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.3314 ORF TRS20 CAL0004070 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.3314 ORF TRS20 CAL0004070 PMID: 21135205|CGD_REF: CAL0139967 heterozygous diploid, competitive growth (large-scale identification of genes essential for virulence in mouse) repressible CAI-4 virulence: normal mouse intravenous infection C. albicans orf19.3315 ORF CTA9 CAL0004073 PMID: 19779551|CGD_REF: CAL0124331 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.3315 ORF CTA9 CAL0004073 PMID: 19779551|CGD_REF: CAL0124331 homozygous diploid, classical genetics null Not recorded colony appearance: abnormal solid Spider medium C. albicans orf19.3315 ORF CTA9 CAL0004073 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.3315 ORF CTA9 CAL0004073 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: abnormal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.3315 ORF CTA9 CAL0004073 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.3315 ORF CTA9 CAL0004073 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.3317 ORF MED22 CAL0004076 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.3318 ORF CAL0004077 PMID: 20494978|CGD_REF: CAL0125636 heterozygous diploid, classical genetics null BWP17 resistance to chemicals: decreased clotrimazole (75 uM) growth in liquid culture confirmation of mutant phenotypes for heterozygous transposon insertion strains showing sensitivity in a large-scale assay C. albicans orf19.3319 ORF CAL0004078 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.332 ORF CAL0004743 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.3321 ORF MRS7 CAL0004088 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.3321 ORF MRS7 CAL0004088 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 invasive growth: decreased solid SLAD media C. albicans orf19.3322 ORF DUT1 CAL0004091 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.3325 ORF CAL0004098 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.3325.3 ORF RPS21B CAF0006982 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient YPD medium C. albicans orf19.3325.3 ORF RPS21B CAF0006982 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient SC medium C. albicans orf19.3325.3 ORF RPS21B CAF0006982 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient SLAD medium C. albicans orf19.3327 ORF TRM2 CAL0004099 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.3329 ORF CAL0004101 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.3329 ORF CAL0004101 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 invasive growth: decreased solid SLAD media C. albicans orf19.333 ORF FCY2 CAL0004745 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, competitive growth (haploinsufficient phenotype assay, barcode deletion set) null SC5314 resistance to chemicals: increased 5-fluorouracil C. albicans orf19.333 ORF FCY2 CAL0004745 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, competitive growth (haploinsufficient phenotype assay, barcode deletion set) null SC5314 resistance to chemicals: increased flucytosine C. albicans orf19.333 ORF FCY2 CAL0004745 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.333 ORF FCY2 CAL0004745 PMID: 12773383|CGD_REF: CAL0087974 heterozygous diploid, classical genetics (haploinsufficient phenotype assay) unspecified CAI-4 filamentous growth: increased solid YEPD plus serum transposon insertion proximal to, but not within, the ORF C. albicans orf19.333 ORF FCY2 CAL0004745 PMID: 15504867|CGD_REF: CAL0082142 unknown ploidy, classical genetics unspecified Other C. albicans resistance to chemicals: increased flucytosine mutation is associated with resistance to flucytosine (5-FC) in clinical isolates but has not been shown to be causative C. albicans orf19.333 ORF FCY2 CAL0004745 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.333 ORF FCY2 CAL0004745 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.333 ORF FCY2 CAL0004745 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: decreased rate liquid synthetic complete medium C. albicans orf19.333 ORF FCY2 CAL0004745 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.333 ORF FCY2 CAL0004745 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 invasive growth: decreased solid SLAD media C. albicans orf19.3330 ORF CRL1 CAL0004109 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.3330 ORF CRL1 CAL0004109 PMID: 17351079|CGD_REF: CAL0117784 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.3330 ORF CRL1 CAL0004109 PMID: 17351079|CGD_REF: CAL0117784 homozygous diploid, classical genetics null Not recorded cell shape: abnormal cells are elongated C. albicans orf19.3330 ORF CRL1 CAL0004109 PMID: 17351079|CGD_REF: CAL0117784 homozygous diploid, classical genetics null Not recorded cytokinesis: absent C. albicans orf19.3330 ORF CRL1 CAL0004109 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.3330 ORF CRL1 CAL0004109 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.3330 ORF CRL1 CAL0004109 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.3330 ORF CRL1 CAL0004109 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.3330.3 ORF POX18 CAF0006983 PMID: 14663094|CGD_REF: CAL0080633 homozygous diploid, systematic mutation set (homozygous insertion mutants generated with URA3-ARG4-URA3 (UAU1) cassette) null BWP17 viable C. albicans orf19.3330.3 ORF POX18 CAF0006983 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.3330.3 ORF POX18 CAF0006983 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.3330.3 ORF POX18 CAF0006983 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.3330.3 ORF POX18 CAF0006983 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.3331 ORF ABC1 CAL0004112 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient YPD medium C. albicans orf19.3332 ORF CAL0004114 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.3333 ORF CAL0004117 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.3333 ORF CAL0004117 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 invasive growth: decreased solid SLAD media C. albicans orf19.3334 ORF RPS21 CAL0004119 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.3335 ORF CAL0004121 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: decreased growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.3335 ORF CAL0004121 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.3335 ORF CAL0004121 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.3335 ORF CAL0004121 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.3340 ORF SOD2 CAL0004132 PMID: 12898709|CGD_REF: CAL0081932 homozygous diploid, classical genetics null Not recorded oxidative stress resistance: increased lithium chloride C. albicans orf19.3340 ORF SOD2 CAL0004132 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.3340 ORF SOD2 CAL0004132 PMID: 12898709|CGD_REF: CAL0081932 heterozygous diploid, classical genetics null Not recorded viable C. albicans orf19.3340 ORF SOD2 CAL0004132 PMID: 12898709|CGD_REF: CAL0081932 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.3340 ORF SOD2 CAL0004132 PMID: 19019164|CGD_REF: CAL0121070 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.3340 ORF SOD2 CAL0004132 PMID: 19019164|CGD_REF: CAL0121070 homozygous diploid, classical genetics null Not recorded interaction with host/environment: normal wild-type reactive oxygen species accumulation during response to macrophages in vitro model of infection C. albicans orf19.3340 ORF SOD2 CAL0004132 PMID: 12898709|CGD_REF: CAL0081932 homozygous diploid, classical genetics null Not recorded oxidative stress resistance: increased diamide C. albicans orf19.3340 ORF SOD2 CAL0004132 PMID: 19019164|CGD_REF: CAL0121070 homozygous diploid, classical genetics null Not recorded oxidative stress resistance: increased diamide C. albicans orf19.3340 ORF SOD2 CAL0004132 PMID: 19019164|CGD_REF: CAL0121070 homozygous diploid, classical genetics null Not recorded oxidative stress resistance: increased diamide C. albicans orf19.3340 ORF SOD2 CAL0004132 PMID: 12898709|CGD_REF: CAL0081932 homozygous diploid, classical genetics null Not recorded oxidative stress resistance: decreased menadione C. albicans orf19.3340 ORF SOD2 CAL0004132 PMID: 19019164|CGD_REF: CAL0121070 homozygous diploid, classical genetics null Not recorded oxidative stress resistance: decreased menadione C. albicans orf19.3340 ORF SOD2 CAL0004132 PMID: 19019164|CGD_REF: CAL0121070 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased menadione C. albicans orf19.3340 ORF SOD2 CAL0004132 PMID: 12898709|CGD_REF: CAL0081932 heterozygous diploid, classical genetics overexpression Not recorded metal resistance: decreased lithium C. albicans orf19.3340 ORF SOD2 CAL0004132 PMID: 12898709|CGD_REF: CAL0081932 homozygous diploid, classical genetics null Not recorded oxidative stress resistance: decreased paraquat C. albicans orf19.3340 ORF SOD2 CAL0004132 PMID: 12898709|CGD_REF: CAL0081932 homozygous diploid, classical genetics null Not recorded virulence: normal mouse intravenous infection C. albicans orf19.3340 ORF SOD2 CAL0004132 PMID: 12898709|CGD_REF: CAL0081932 heterozygous diploid, classical genetics overexpression Not recorded virulence: normal mouse intravenous infection C. albicans orf19.3341 ORF CAL0004134 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.3341 ORF CAL0004134 PMID: 16607011|CGD_REF: CAL0115846 heterozygous diploid, classical genetics null SC5314 viable C. albicans orf19.3341 ORF CAL0004134 PMID: 16607011|CGD_REF: CAL0115846 homozygous diploid, classical genetics null SC5314 inviable homozygous null mutant strain could not be recovered, suggesting that the gene is essential under the selection conditions C. albicans orf19.3341 ORF CAL0004134 PMID: 16607011|CGD_REF: CAL0115846 heterozygous diploid, classical genetics repressible SC5314 inviable C. albicans orf19.3345 ORF SIZ1 CAL0004141 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.3345 ORF SIZ1 CAL0004141 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.3345 ORF SIZ1 CAL0004141 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.3345 ORF SIZ1 CAL0004141 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.3345 ORF SIZ1 CAL0004141 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient YNB medium C. albicans orf19.3345 ORF SIZ1 CAL0004141 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.3347 ORF RPB7 CAL0004143 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.3347 ORF RPB7 CAL0004143 PMID: 19623926|CGD_REF: CAL0124054 heterozygous diploid, competitive growth (haploinsufficient phenotype assay, barcode deletion set) null SC5314 resistance to chemicals: increased parnafungin C. albicans orf19.3348 ORF CAL0004144 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.3348 ORF CAL0004144 PMID: 21135205|CGD_REF: CAL0139967 heterozygous diploid, large-scale survey (large-scale identification of genes essential for virulence in mouse) repressible CAI-4 virulence: absent mouse intravenous infection C. albicans orf19.3349 ORF CAL0004145 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.3349 ORF CAL0004145 PMID: 19623926|CGD_REF: CAL0124054 heterozygous diploid, competitive growth (haploinsufficient phenotype assay, barcode deletion set) null SC5314 resistance to chemicals: increased parnafungin C. albicans orf19.335 ORF CAL0004749 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.335 ORF CAL0004749 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.335 ORF CAL0004749 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.335 ORF CAL0004749 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.3352 ORF CAL0004153 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.3353 ORF CAL0004155 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 invasive growth: decreased solid SLAD media C. albicans orf19.3355 ORF ISN1 CAL0004158 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.3355 ORF ISN1 CAL0004158 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient YPD medium C. albicans orf19.3355 ORF ISN1 CAL0004158 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient SC medium C. albicans orf19.3355 ORF ISN1 CAL0004158 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient YNB medium C. albicans orf19.3355 ORF ISN1 CAL0004158 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient SLAD medium C. albicans orf19.3356 ORF ESP1 CAL0004160 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.3356 ORF ESP1 CAL0004160 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, competitive growth (haploinsufficient phenotype assay, barcode deletion set) null SC5314 resistance to chemicals: decreased nocodazole C. albicans orf19.3358 ORF LSC1 CAL0004162 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.3359 ORF ARP8 CAL0004163 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.3359 ORF ARP8 CAL0004163 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, competitive growth (haploinsufficient phenotype assay, barcode deletion set) null SC5314 resistance to chemicals: decreased amphotericin B C. albicans orf19.3359 ORF ARP8 CAL0004163 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, competitive growth (haploinsufficient phenotype assay, barcode deletion set) null SC5314 resistance to chemicals: decreased ergosterol analogs (ECC69 and/or ECC1384) C. albicans orf19.3359 ORF ARP8 CAL0004163 PMID: 19115836|CGD_REF: CAL0122036 heterozygous diploid, competitive growth (haploinsufficient phenotype assay, barcode deletion set) null SC5314 resistance to chemicals: decreased virgineone C. albicans orf19.336 ORF YAH1 CAL0004752 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.336 ORF YAH1 CAL0004752 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 invasive growth: decreased solid SLAD media C. albicans orf19.3364 ORF CAL0004173 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient SC medium C. albicans orf19.3364 ORF CAL0004173 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient YNB medium C. albicans orf19.3364 ORF CAL0004173 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient SLAD medium C. albicans orf19.3365 ORF DAO2 CAL0004175 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.3366 ORF CSH3 CAL0004176 PMID: 14756779|CGD_REF: CAL0081087 homozygous diploid, classical genetics null CAI-4 germ tube formation: normal liquid Lee's medium C. albicans orf19.3366 ORF CSH3 CAL0004176 PMID: 14756779|CGD_REF: CAL0081087 homozygous diploid, classical genetics null Not recorded small molecule transport: abnormal abolished lysine or phenylalanine transport; decreased histidine or proline transport; increased adenine transport C. albicans orf19.3366 ORF CSH3 CAL0004176 PMID: 14756779|CGD_REF: CAL0081087 heterozygous diploid, classical genetics null Not recorded small molecule transport: abnormal increased adenine transport, slightly decreased lysine, phenylalanine, or proline transport C. albicans orf19.3366 ORF CSH3 CAL0004176 PMID: 14756779|CGD_REF: CAL0081087 homozygous diploid, classical genetics null CAI-4 hyphal growth: decreased decreased hyphal induction by proline C. albicans orf19.3366 ORF CSH3 CAL0004176 PMID: 14756779|CGD_REF: CAL0081087 heterozygous diploid, classical genetics null CAI-4 hyphal growth: normal solid Spider or serum-containing media C. albicans orf19.3366 ORF CSH3 CAL0004176 PMID: 14756779|CGD_REF: CAL0081087 heterozygous diploid, classical genetics null CAI-4 hyphal growth: normal normal hyphal induction by proline C. albicans orf19.3366 ORF CSH3 CAL0004176 PMID: 14756779|CGD_REF: CAL0081087 heterozygous diploid, classical genetics null CAI-4 hyphal growth: normal GlcNAc-containing medium C. albicans orf19.3366 ORF CSH3 CAL0004176 PMID: 14756779|CGD_REF: CAL0081087 homozygous diploid, classical genetics null CAI-4 hyphal growth: normal GlcNAc-containing medium C. albicans orf19.3366 ORF CSH3 CAL0004176 PMID: 14756779|CGD_REF: CAL0081087 homozygous diploid, classical genetics null CAI-4 hyphal growth: absent liquid Lee's medium C. albicans orf19.3366 ORF CSH3 CAL0004176 PMID: 14756779|CGD_REF: CAL0081087 heterozygous diploid, classical genetics null CAI-4 hyphal growth: normal liquid Lee's medium C. albicans orf19.3366 ORF CSH3 CAL0004176 PMID: 14756779|CGD_REF: CAL0081087 homozygous diploid, classical genetics null CAI-4 hyphal growth: normal M199 pH 8 medium C. albicans orf19.3366 ORF CSH3 CAL0004176 PMID: 14756779|CGD_REF: CAL0081087 homozygous diploid, classical genetics null CAI-4 hyphal growth: decreased solid Spider or serum-containing media C. albicans orf19.3366 ORF CSH3 CAL0004176 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.3366 ORF CSH3 CAL0004176 PMID: 14756779|CGD_REF: CAL0081087 heterozygous diploid, classical genetics null Not recorded viable C. albicans orf19.3366 ORF CSH3 CAL0004176 PMID: 14756779|CGD_REF: CAL0081087 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.3366 ORF CSH3 CAL0004176 PMID: 16227594|CGD_REF: CAL0114869 homozygous diploid, classical genetics null Not recorded protein/peptide modification: absent Stp2p and Stp3p are not proteolytically processed in response to amino acids, as in wild type Stp2p C. albicans orf19.3366 ORF CSH3 CAL0004176 PMID: 14756779|CGD_REF: CAL0081087 homozygous diploid, classical genetics null Not recorded resistance to chemicals: increased D-lysine high concentrations C. albicans orf19.3366 ORF CSH3 CAL0004176 PMID: 14756779|CGD_REF: CAL0081087 heterozygous diploid, classical genetics null Not recorded resistance to chemicals: increased D-lysine C. albicans orf19.3366 ORF CSH3 CAL0004176 PMID: 14756779|CGD_REF: CAL0081087 heterozygous diploid, classical genetics null Not recorded utilization of nitrogen source: decreased citrulline phenotype is intermediate between that of wild type and the homozygous null mutant C. albicans orf19.3366 ORF CSH3 CAL0004176 PMID: 14756779|CGD_REF: CAL0081087 homozygous diploid, classical genetics null Not recorded utilization of nitrogen source: decreased citrulline C. albicans orf19.3366 ORF CSH3 CAL0004176 PMID: 14756779|CGD_REF: CAL0081087 homozygous diploid, classical genetics null Not recorded utilization of nitrogen source: decreased amino acid C. albicans orf19.3366 ORF CSH3 CAL0004176 PMID: 14756779|CGD_REF: CAL0081087 heterozygous diploid, classical genetics null Not recorded resistance to chemicals: increased thialysine C. albicans orf19.3366 ORF CSH3 CAL0004176 PMID: 14756779|CGD_REF: CAL0081087 homozygous diploid, classical genetics null Not recorded resistance to chemicals: increased thialysine C. albicans orf19.3366 ORF CSH3 CAL0004176 PMID: 14756779|CGD_REF: CAL0081087 heterozygous diploid, classical genetics null Not recorded virulence: decreased mouse intravenous infection C. albicans orf19.3366 ORF CSH3 CAL0004176 PMID: 14756779|CGD_REF: CAL0081087 homozygous diploid, classical genetics null Not recorded virulence: decreased mouse intravenous infection C. albicans orf19.3368 ORF CAL0004178 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.337 ORF VTI1 CAL0004755 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.337 ORF VTI1 CAL0004755 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 invasive growth: decreased solid SLAD media C. albicans orf19.337 ORF VTI1 CAL0004755 PMID: 21135205|CGD_REF: CAL0139967 heterozygous diploid, large-scale survey (large-scale identification of genes essential for virulence in mouse) repressible CAI-4 virulence: absent mouse intravenous infection C. albicans orf19.3370 ORF DOT4 CAL0004185 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.3370 ORF DOT4 CAL0004185 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.3370 ORF DOT4 CAL0004185 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: decreased rate liquid synthetic complete medium C. albicans orf19.3370 ORF DOT4 CAL0004185 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.3371 ORF JAB1 CAL0004187 PMID: 22080453|CGD_REF: CAL0000143626 homozygous diploid, classical genetics null Other C. albicans viable C. albicans orf19.3374 ORF ECE1 CAL0004191 PMID: 8359888|CGD_REF: CAL0081161 homozygous diploid, classical genetics null CAI-4 hyphal growth: normal various inducing conditions C. albicans orf19.3374 ORF ECE1 CAL0004191 PMID: 8349105|CGD_REF: CAL0082009 heterozygous diploid, classical genetics null Not recorded viable C. albicans orf19.3374 ORF ECE1 CAL0004191 PMID: 8349105|CGD_REF: CAL0082009 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.3374 ORF ECE1 CAL0004191 PMID: 8359888|CGD_REF: CAL0081161 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.3374 ORF ECE1 CAL0004191 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.3374 ORF ECE1 CAL0004191 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.3374 ORF ECE1 CAL0004191 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.3374 ORF ECE1 CAL0004191 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.338 ORF CAL0004758 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.3380 ORF HWP2 CAL0004200 PMID: 18765290|CGD_REF: CAL0119430 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.3380 ORF HWP2 CAL0004200 PMID: 19616419|CGD_REF: CAL0123911 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.3380 ORF HWP2 CAL0004200 PMID: 19616419|CGD_REF: CAL0123911 homozygous diploid, classical genetics null RM1000 viable C. albicans orf19.3380 ORF HWP2 CAL0004200 PMID: 19616419|CGD_REF: CAL0123911 homozygous diploid, classical genetics null RM1000 filamentous growth: absent Sabouraud dextrose agar (phenotype is also observed on cornmeal agar) C. albicans orf19.3380 ORF HWP2 CAL0004200 PMID: 19616419|CGD_REF: CAL0123911 homozygous diploid, classical genetics null RM1000 virulence: decreased infected mice survive for 11 days as compared to 6 days for wild-type infection mouse intravenous infection C. albicans orf19.3380 ORF HWP2 CAL0004200 PMID: 19837954|CGD_REF: CAL0124430 homozygous diploid, classical genetics null SC5314 mating efficiency: decreased C. albicans orf19.3380 ORF HWP2 CAL0004200 PMID: 19837954|CGD_REF: CAL0124430 homozygous diploid, classical genetics null SC5314 biofilm formation: decreased C. albicans orf19.3380 ORF HWP2 CAL0004200 PMID: 19616419|CGD_REF: CAL0123911 homozygous diploid, classical genetics null Not recorded filamentous growth: absent Sabouraud dextrose agar or cornmeal agar C. albicans orf19.3380 ORF HWP2 CAL0004200 PMID: 20869222|CGD_REF: CAL0126467 homozygous diploid, classical genetics null RM1000 resistance to chemicals: decreased hydrogen peroxide (50mM) C. albicans orf19.3380 ORF HWP2 CAL0004200 PMID: 20869222|CGD_REF: CAL0126467 heterozygous diploid, classical genetics null RM1000 resistance to chemicals: decreased hydrogen peroxide (50mM) C. albicans orf19.3380 ORF HWP2 CAL0004200 PMID: 20869222|CGD_REF: CAL0126467 homozygous diploid, classical genetics null RM1000 resistance to chemicals: decreased Congo Red (200 micrograms/mL) C. albicans orf19.3380 ORF HWP2 CAL0004200 PMID: 20869222|CGD_REF: CAL0126467 heterozygous diploid, classical genetics null RM1000 resistance to chemicals: decreased Congo Red (200 micrograms/mL) C. albicans orf19.3380 ORF HWP2 CAL0004200 PMID: 20869222|CGD_REF: CAL0126467 homozygous diploid, classical genetics null RM1000 biofilm formation: decreased polystyrene plastic microtiter plates C. albicans orf19.3380 ORF HWP2 CAL0004200 PMID: 20869222|CGD_REF: CAL0126467 heterozygous diploid, classical genetics null RM1000 biofilm formation: decreased polystyrene plastic microtiter plates heterozygous HWP2/hwp2 displays an intermediate phenotype between the nulll and wild-type C. albicans orf19.3380 ORF HWP2 CAL0004200 PMID: 20869222|CGD_REF: CAL0126467 homozygous diploid, classical genetics null RM1000 resistance to chemicals: decreased sodium dodecyl sulfate (0.03%) C. albicans orf19.3380 ORF HWP2 CAL0004200 PMID: 20869222|CGD_REF: CAL0126467 homozygous diploid, classical genetics null RM1000 adhesion: decreased similar results obtained with both the human epithelial cell line HT-29 and the human endothelial cell line ECV304 C. albicans orf19.3380 ORF HWP2 CAL0004200 PMID: 20869222|CGD_REF: CAL0126467 heterozygous diploid, classical genetics null RM1000 adhesion: decreased similar results obtained with both the human epithelial cell line HT-29 and the human endothelial cell line ECV304 C. albicans orf19.3380 ORF HWP2 CAL0004200 PMID: 20869222|CGD_REF: CAL0126467 homozygous diploid, classical genetics null RM1000 chemical compound accumulation: decreased chitin approximately 20% reduction from wild-type levels C. albicans orf19.3380 ORF HWP2 CAL0004200 PMID: 20869222|CGD_REF: CAL0126467 heterozygous diploid, classical genetics null RM1000 chemical compound accumulation: decreased chitin approximately 10% reduction from wild-type levels C. albicans orf19.3380 ORF HWP2 CAL0004200 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.3380 ORF HWP2 CAL0004200 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.3380 ORF HWP2 CAL0004200 PMID: 19616419|CGD_REF: CAL0123911 homozygous diploid, classical genetics null Not recorded virulence: decreased infected mice die after 11 days as compared to 6 days for wild-type infection mouse intravenous infection C. albicans orf19.3380 ORF HWP2 CAL0004200 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.3380 ORF HWP2 CAL0004200 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.339 ORF NDE1 CAL0004762 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.339 ORF NDE1 CAL0004762 PMID: 14507372|CGD_REF: CAL0088818 heterozygous diploid, large-scale survey (large-scale identification of essential genes by gene replacement and conditional expression (GRACE) method) repressible CAI-4 viable one allele is deleted and the other is placed under repressible Tet promoter C. albicans orf19.339 ORF NDE1 CAL0004762 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 invasive growth: decreased solid SLAD media C. albicans orf19.3391 ORF ADK1 CAL0004216 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.3392 ORF DOG1 CAL0004218 PMID: 15796987|CGD_REF: CAL0104027 heterozygous diploid, classical genetics repressible Not recorded viable C. albicans orf19.3392 ORF DOG1 CAL0004218 PMID: 15796987|CGD_REF: CAL0104027 homozygous diploid, classical genetics null Not recorded inviable homozygous null mutant strain could not be recovered, suggesting that the gene is essential under the selection conditions C. albicans orf19.3392 ORF DOG1 CAL0004218 PMID: 15796987|CGD_REF: CAL0104027 heterozygous diploid, classical genetics repressible Not recorded osmotic stress resistance: normal C. albicans orf19.3392 ORF DOG1 CAL0004218 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient YPD medium C. albicans orf19.3392 ORF DOG1 CAL0004218 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient SC medium C. albicans orf19.3393 ORF CAL0004220 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.3395 ORF CAL0004224 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.3395 ORF CAL0004224 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.3395 ORF CAL0004224 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.3395 ORF CAL0004224 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.3395 ORF CAL0004224 PMID: 20494978|CGD_REF: CAL0125636 heterozygous diploid, classical genetics null BWP17 resistance to chemicals: decreased clotrimazole (75 uM) growth in liquid culture confirmation of mutant phenotypes for heterozygous transposon insertion strains showing sensitivity in a large-scale assay C. albicans orf19.3395 ORF CAL0004224 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.3396 ORF HCH1 CAL0004225 PMID: 14663094|CGD_REF: CAL0080633 homozygous diploid, systematic mutation set (homozygous insertion mutants generated with URA3-ARG4-URA3 (UAU1) cassette) null BWP17 viable C. albicans orf19.3396 ORF HCH1 CAL0004225 PMID: 19115836|CGD_REF: CAL0122036 heterozygous diploid, competitive growth (haploinsufficient phenotype assay, barcode deletion set) null SC5314 resistance to chemicals: increased virgineone C. albicans orf19.3396 ORF HCH1 CAL0004225 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.3396 ORF HCH1 CAL0004225 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.3396 ORF HCH1 CAL0004225 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.3396 ORF HCH1 CAL0004225 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.3399 ORF CAL0004226 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.34 ORF GIT1 CAL0000550 PMID: 21984707|CGD_REF: CAL0000143468 homozygous diploid, classical genetics null git1:UAU1/git1::URA3 BWP17 viable C. albicans orf19.34 ORF GIT1 CAL0000550 PMID: 21984707|CGD_REF: CAL0000143468 homozygous diploid, classical genetics null git1:UAU1/git1::URA3 BWP17 utilization of phosphorus source: decreased glycerophosphoinositol C. albicans orf19.3400 ORF COQ3 CAL0004858 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.3401 ORF CTA1 CAL0004860 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.3401 ORF CTA1 CAL0004860 PMID: 15664973|CGD_REF: CAL0103941 heterozygous diploid, classical genetics null Not recorded viable C. albicans orf19.3401 ORF CTA1 CAL0004860 PMID: 15664973|CGD_REF: CAL0103941 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.3401 ORF CTA1 CAL0004860 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, competitive growth (haploinsufficient phenotype assay, barcode deletion set) null SC5314 resistance to chemicals: decreased amphotericin B C. albicans orf19.3402 ORF FPG1 CAL0004863 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.3402 ORF FPG1 CAL0004863 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.3402 ORF FPG1 CAL0004863 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.3402 ORF FPG1 CAL0004863 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.3402 ORF FPG1 CAL0004863 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.3404 ORF CAL0004866 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.3404 ORF CAL0004866 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.3404 ORF CAL0004866 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.3404 ORF CAL0004866 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient SC medium C. albicans orf19.3404 ORF CAL0004866 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.3404 ORF CAL0004866 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 invasive growth: decreased solid SLAD media C. albicans orf19.3405 ORF ZCF18 CAL0004869 PMID: 15964282|CGD_REF: CAL0114274 homozygous diploid, systematic mutation set (split-marker transposon insertion strategy to disrupt both alleles) null BWP17 viable C. albicans orf19.3405 ORF ZCF18 CAL0004869 PMID: 15964282|CGD_REF: CAL0114274 homozygous diploid, systematic mutation set (split-marker transposon insertion strategy to disrupt both alleles) null BWP17 biofilm formation: normal C. albicans orf19.3405 ORF ZCF18 CAL0004869 PMID: 19115836|CGD_REF: CAL0122036 heterozygous diploid, competitive growth (haploinsufficient phenotype assay, barcode deletion set) null SC5314 resistance to chemicals: decreased virgineone C. albicans orf19.3405 ORF ZCF18 CAL0004869 PMID: 22073120|CGD_REF: CAL0000143592 homozygous diploid, classical genetics null BWP17 viable C. albicans orf19.3405 ORF ZCF18 CAL0004869 PMID: 22073120|CGD_REF: CAL0000143592 homozygous diploid, classical genetics null BWP17 hyphal growth: increased C. albicans orf19.3407 ORF RAD18 CAL0004874 PMID: 15964282|CGD_REF: CAL0114274 homozygous diploid, systematic mutation set (split-marker transposon insertion strategy to disrupt both alleles) null BWP17 viable C. albicans orf19.3407 ORF RAD18 CAL0004874 PMID: 15964282|CGD_REF: CAL0114274 homozygous diploid, systematic mutation set (split-marker transposon insertion strategy to disrupt both alleles) null BWP17 biofilm formation: normal C. albicans orf19.3407 ORF RAD18 CAL0004874 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.3407 ORF RAD18 CAL0004874 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.3407 ORF RAD18 CAL0004874 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.3407 ORF RAD18 CAL0004874 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.3409 ORF SEC12 CAL0004877 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.341 ORF CAL0004786 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.341 ORF CAL0004786 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.341 ORF CAL0004786 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.341 ORF CAL0004786 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.341 ORF CAL0004786 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.3411 ORF CAL0004890 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.3412 ORF ATG15 CAL0004893 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.3412 ORF ATG15 CAL0004893 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.3412 ORF ATG15 CAL0004893 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.3412 ORF ATG15 CAL0004893 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.3412 ORF ATG15 CAL0004893 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.3413 ORF FGR37 CAL0004895 PMID: 12773383|CGD_REF: CAL0087974 heterozygous diploid, classical genetics (haploinsufficient phenotype assay) null CAI-4 viable heterozygous transposon insertion C. albicans orf19.3413 ORF FGR37 CAL0004895 PMID: 12773383|CGD_REF: CAL0087974 heterozygous diploid, classical genetics (haploinsufficient phenotype assay) null CAI-4 filamentous growth: increased solid Spider medium heterozygous transposon insertion C. albicans orf19.3414 ORF SUR7 CAL0004898 PMID: 18799621|CGD_REF: CAL0120254 homozygous diploid, classical genetics null BWP17 hyphal growth: abnormal liquid serum or GlcNAc media abnormal morphology of cells responding to hyphal induction conditions C. albicans orf19.3414 ORF SUR7 CAL0004898 PMID: 18799621|CGD_REF: CAL0120254 heterozygous diploid, classical genetics null Not recorded viable C. albicans orf19.3414 ORF SUR7 CAL0004898 PMID: 18799621|CGD_REF: CAL0120254 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.3414 ORF SUR7 CAL0004898 PMID: 18799621|CGD_REF: CAL0120254 homozygous diploid, classical genetics null Not recorded actin cytoskeleton morphology: abnormal depolarized cortical actin patches and septin mislocalization C. albicans orf19.3414 ORF SUR7 CAL0004898 PMID: 18799621|CGD_REF: CAL0120254 homozygous diploid, classical genetics null BWP17 invasive growth: decreased solid serum- or GlcNAc-containing media C. albicans orf19.3414 ORF SUR7 CAL0004898 PMID: 18799621|CGD_REF: CAL0120254 homozygous diploid, classical genetics null Not recorded cell wall morphology: abnormal cell wall exhibits gross abnormalities, including growth of intracellular cell wall structures C. albicans orf19.3414 ORF SUR7 CAL0004898 PMID: 18799621|CGD_REF: CAL0120254 homozygous diploid, classical genetics null Not recorded chitin deposition: increased C. albicans orf19.3414 ORF SUR7 CAL0004898 PMID: 18799621|CGD_REF: CAL0120254 homozygous diploid, classical genetics null Not recorded endocytosis: delayed delay in endocytosis and vacuolar trafficking of FM 4-64 dye or a ligand-bound receptor reporter C. albicans orf19.3414 ORF SUR7 CAL0004898 PMID: 18799621|CGD_REF: CAL0120254 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased fluconazole C. albicans orf19.3414 ORF SUR7 CAL0004898 PMID: 22202230|CGD_REF: CAL0000143762 homozygous diploid, classical genetics null BWP17 resistance to chemicals: decreased menadione C. albicans orf19.3414 ORF SUR7 CAL0004898 PMID: 22202230|CGD_REF: CAL0000143762 homozygous diploid, classical genetics null BWP17 resistance to chemicals: decreased hydrogen peroxide C. albicans orf19.3414 ORF SUR7 CAL0004898 PMID: 22202230|CGD_REF: CAL0000143762 homozygous diploid, classical genetics null BWP17 resistance to chemicals: decreased cadmium dichloride C. albicans orf19.3414 ORF SUR7 CAL0004898 PMID: 22202230|CGD_REF: CAL0000143762 homozygous diploid, classical genetics null BWP17 resistance to chemicals: decreased copper(2+) sulfate C. albicans orf19.3414 ORF SUR7 CAL0004898 PMID: 22202230|CGD_REF: CAL0000143762 homozygous diploid, classical genetics null BWP17 resistance to chemicals: decreased cumene hydroperoxide C. albicans orf19.3414 ORF SUR7 CAL0004898 PMID: 22202230|CGD_REF: CAL0000143762 homozygous diploid, classical genetics null BWP17 resistance to chemicals: decreased diamide C. albicans orf19.3414 ORF SUR7 CAL0004898 PMID: 22202230|CGD_REF: CAL0000143762 homozygous diploid, classical genetics null BWP17 virulence: decreased mouse intravenous infection C. albicans orf19.3414 ORF SUR7 CAL0004898 PMID: 20433738|CGD_REF: CAL0125748 homozygous diploid, classical genetics null BWP17 heat sensitivity: increased 42 degrees C impaired growth at 42 degrees C is partially overcome by the addition of 1M NaCl C. albicans orf19.3414 ORF SUR7 CAL0004898 PMID: 20433738|CGD_REF: CAL0125748 homozygous diploid, classical genetics null BWP17 resistance to chemicals: decreased caspofungin (0.25 micrograms/ml) C. albicans orf19.3414 ORF SUR7 CAL0004898 PMID: 20433738|CGD_REF: CAL0125748 homozygous diploid, classical genetics null BWP17 resistance to chemicals: decreased Calcofluor White|Congo Red|sodium dodecyl sulfate C. albicans orf19.3414 ORF SUR7 CAL0004898 PMID: 20433738|CGD_REF: CAL0125748 homozygous diploid, classical genetics null BWP17 hyphal growth: abnormal yeast cells and hyphae with aberrant morphology and branching C. albicans orf19.3414 ORF SUR7 CAL0004898 PMID: 20433738|CGD_REF: CAL0125748 heterozygous diploid, classical genetics null BWP17 resistance to chemicals: decreased Calcofluor White|Congo Red|sodium dodecyl sulfate C. albicans orf19.3414 ORF SUR7 CAL0004898 PMID: 20433738|CGD_REF: CAL0125748 homozygous diploid, classical genetics null BWP17 hyphal growth: decreased M199 agar or Spider agar at 37 degrees C C. albicans orf19.3414 ORF SUR7 CAL0004898 PMID: 20433738|CGD_REF: CAL0125748 homozygous diploid, classical genetics null BWP17 germ tube formation: decreased C. albicans orf19.3414 ORF SUR7 CAL0004898 PMID: 20433738|CGD_REF: CAL0125748 homozygous diploid, classical genetics null BWP17 protein/peptide accumulation: increased Sap2p C. albicans orf19.3414 ORF SUR7 CAL0004898 PMID: 20433738|CGD_REF: CAL0125748 heterozygous diploid, classical genetics null BWP17 resistance to chemicals: decreased caspofungin (0.25 micrograms/ml) defect is intermediate between wil-type (2 copies) and the heterozygote or complemented strains (one copy) C. albicans orf19.3414 ORF SUR7 CAL0004898 PMID: 20433738|CGD_REF: CAL0125748 homozygous diploid, classical genetics null BWP17 plasma membrane morphology: abnormal subcellular invaginations that appear to be plasma membrane observed in mutants (electron microscopy) C. albicans orf19.3414 ORF SUR7 CAL0004898 PMID: 20433738|CGD_REF: CAL0125748 homozygous diploid, classical genetics null BWP17 biofilm formation: abnormal sparse biofilm architecture observed by scanning electron microscopy C. albicans orf19.3414 ORF SUR7 CAL0004898 PMID: 20433738|CGD_REF: CAL0125748 homozygous diploid, classical genetics null BWP17 virulence: decreased J774A.1 murine macrophage cell-line decreased killing of macrophages, MOI 2 in vitro model of infection C. albicans orf19.3414 ORF SUR7 CAL0004898 PMID: 21115741|CGD_REF: CAL0139952 homozygous diploid, classical genetics null sur7::UAU/sur7::URA3 BWP17 bud morphology: abnormal C. albicans orf19.3414 ORF SUR7 CAL0004898 PMID: 21115741|CGD_REF: CAL0139952 homozygous diploid, classical genetics null sur7::UAU/sur7::URA3 BWP17 cell shape: abnormal C. albicans orf19.3414 ORF SUR7 CAL0004898 PMID: 21115741|CGD_REF: CAL0139952 homozygous diploid, classical genetics null sur7::UAU/sur7::URA3 BWP17 resistance to chemicals: decreased cercosporamide C. albicans orf19.3414 ORF SUR7 CAL0004898 PMID: 21115741|CGD_REF: CAL0139952 homozygous diploid, classical genetics null sur7::UAU/sur7::URA3 BWP17 resistance to chemicals: decreased cercosporamide|nikkomycin Z C. albicans orf19.3415 ORF PTK2 CAL0004902 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.3415 ORF PTK2 CAL0004902 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, competitive growth (haploinsufficient phenotype assay, barcode deletion set) null SC5314 resistance to chemicals: decreased tunicamycin C. albicans orf19.3415.1 ORF RPL32 CAF0006985 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient YPD medium C. albicans orf19.3415.1 ORF RPL32 CAF0006985 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient SC medium C. albicans orf19.3415.1 ORF RPL32 CAF0006985 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient YNB medium C. albicans orf19.3415.1 ORF RPL32 CAF0006985 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient SLAD medium C. albicans orf19.3417 ORF ACF2 CAL0004906 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.3417 ORF ACF2 CAL0004906 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.3417 ORF ACF2 CAL0004906 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.3417 ORF ACF2 CAL0004906 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.3417 ORF ACF2 CAL0004906 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.3418 ORF CAL0004907 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.3418 ORF CAL0004907 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.3418 ORF CAL0004907 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.3418 ORF CAL0004907 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.3418 ORF CAL0004907 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.3419 ORF MAE1 CAL0004908 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.342 ORF BMT7 CAL0004787 PMID: 18234669|CGD_REF: CAL0119018 homozygous diploid, classical genetics null Not recorded resistance to chemicals: normal Calcofluor White C. albicans orf19.342 ORF BMT7 CAL0004787 PMID: 18234669|CGD_REF: CAL0119018 homozygous diploid, classical genetics null Not recorded resistance to chemicals: normal sodium dodecyl sulfate C. albicans orf19.342 ORF BMT7 CAL0004787 PMID: 18234669|CGD_REF: CAL0119018 homozygous diploid, classical genetics null BWP17 hyphal growth: normal serum-containing medium C. albicans orf19.342 ORF BMT7 CAL0004787 PMID: 18234669|CGD_REF: CAL0119018 homozygous diploid, classical genetics null Not recorded viable rich medium wild-type growth rate C. albicans orf19.342 ORF BMT7 CAL0004787 PMID: 18234669|CGD_REF: CAL0119018 homozygous diploid, classical genetics null Not recorded chlamydospore formation: normal RAT medium C. albicans orf19.342 ORF BMT7 CAL0004787 PMID: 18234669|CGD_REF: CAL0119018 homozygous diploid, classical genetics null Not recorded ionic stress resistance: normal sodium chloride C. albicans orf19.342 ORF BMT7 CAL0004787 PMID: 18234669|CGD_REF: CAL0119018 homozygous diploid, classical genetics null Not recorded resistance to chemicals: normal calcium dichloride C. albicans orf19.3422 ORF FMP27 CAL0004921 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.3422 ORF FMP27 CAL0004921 PMID: 14507372|CGD_REF: CAL0088818 heterozygous diploid, large-scale survey (large-scale identification of essential genes by gene replacement and conditional expression (GRACE) method) repressible CAI-4 viable one allele is deleted and the other is placed under repressible Tet promoter C. albicans orf19.3422 ORF FMP27 CAL0004921 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.3422 ORF FMP27 CAL0004921 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.3422 ORF FMP27 CAL0004921 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.3422 ORF FMP27 CAL0004921 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.3426 ORF ANB1 CAL0004932 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.3429 ORF FGR47 CAL0004937 PMID: 12773383|CGD_REF: CAL0087974 heterozygous diploid, classical genetics (haploinsufficient phenotype assay) unspecified CAI-4 filamentous growth: decreased solid Spider medium transposon insertion proximal to, but not within, the ORF C. albicans orf19.3429 ORF FGR47 CAL0004937 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 invasive growth: decreased solid SLAD media C. albicans orf19.3430 ORF CAL0004951 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 invasive growth: decreased solid SLAD media C. albicans orf19.3431 ORF CAL0004952 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.3432 ORF CAL0004954 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.3434 ORF TRY5 CAL0004960 PMID: 17873081|CGD_REF: CAL0118685 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.3434 ORF TRY5 CAL0004960 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.3434 ORF TRY5 CAL0004960 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.3434 ORF TRY5 CAL0004960 PMID: 22359502|CGD_REF: CAL0000144048 homozygous diploid, classical genetics null BWP17 viable insertion mutant, independent SN152 deletion mutant strain also tested C. albicans orf19.3434 ORF TRY5 CAL0004960 PMID: 22359502|CGD_REF: CAL0000144048 homozygous diploid, classical genetics null BWP17 adhesion: decreased insertion mutant, independent SN152 deletion mutant strain also tested C. albicans orf19.3434 ORF TRY5 CAL0004960 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.3434 ORF TRY5 CAL0004960 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.3437 ORF CAL0004970 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient YPD medium C. albicans orf19.3437 ORF CAL0004970 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient YNB medium C. albicans orf19.3437 ORF CAL0004970 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient SLAD medium C. albicans orf19.3438 ORF CAL0004972 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.3438 ORF CAL0004972 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.3438 ORF CAL0004972 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.3438 ORF CAL0004972 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.3438 ORF CAL0004972 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.344 ORF CAL0004790 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 invasive growth: decreased solid SLAD media C. albicans orf19.3440 ORF FRP5 CAL0004983 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 invasive growth: decreased solid SLAD media C. albicans orf19.3441 ORF FRP6 CAL0004985 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.3444 ORF CAL0004991 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.3445 ORF HOC1 CAL0004993 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.3447 ORF CAL0004996 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.3449 ORF CAL0004998 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.3449 ORF CAL0004998 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.3449 ORF CAL0004998 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.3449 ORF CAL0004998 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.3449 ORF CAL0004998 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.3449 ORF CAL0004998 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 invasive growth: decreased solid SLAD media C. albicans orf19.345 ORF CAL0004793 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.3453 ORF CAL0005008 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.3453 ORF CAL0005008 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.3453 ORF CAL0005008 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.3453 ORF CAL0005008 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.3456 ORF CAL0005012 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.3457 ORF SWD3 CAL0005013 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.3458 ORF CAL0005014 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.3459 ORF CAL0005015 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.3459 ORF CAL0005015 PMID: 22427429|CGD_REF: CAL0000156990 homozygous diploid, classical genetics null BWP17 viable C. albicans orf19.346 ORF ALT1 CAL0004796 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, competitive growth (haploinsufficient phenotype assay, barcode deletion set) null SC5314 resistance to chemicals: decreased flucytosine C. albicans orf19.346 ORF ALT1 CAL0004796 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.3462 ORF SAR1 CAL0005033 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.3466 ORF CAL0005038 PMID: 20494978|CGD_REF: CAL0125636 heterozygous diploid, classical genetics null BWP17 resistance to chemicals: decreased clotrimazole (75 uM) growth in liquid culture confirmation of mutant phenotypes for heterozygous transposon insertion strains showing sensitivity in a large-scale assay C. albicans orf19.3467 ORF SEC27 CAL0005039 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.3467 ORF SEC27 CAL0005039 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient SLAD medium C. albicans orf19.3468 ORF ALG11 CAL0005040 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.3468 ORF ALG11 CAL0005040 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient YPD medium C. albicans orf19.3468 ORF ALG11 CAL0005040 PMID: 21135205|CGD_REF: CAL0139967 heterozygous diploid, competitive growth (large-scale identification of genes essential for virulence in mouse) repressible CAI-4 virulence: decreased mouse intravenous infection C. albicans orf19.3470 ORF CAL0005055 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.3470 ORF CAL0005055 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.3470 ORF CAL0005055 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.3470 ORF CAL0005055 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.3474 ORF IPL1 CAL0005060 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.3474 ORF IPL1 CAL0005060 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient SLAD medium C. albicans orf19.3476 ORF HRR25 CAL0005063 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.3477 ORF CAL0005064 PMID: 23572557|CGD_REF: CAL0000158900 homozygous diploid, classical genetics null BWP17 resistance to chemicals: decreased fluconazole RPMI+MOPS+Histidine medium , 6 hours without shaking at 37 degrees C 24 hr fluconazole treatment in 96 well plates C. albicans orf19.3477 ORF CAL0005064 PMID: 23572557|CGD_REF: CAL0000158900 homozygous diploid, classical genetics null BWP17 adhesion: increased Fluxion Bioflux 200, equipped with a microscope, was used for adherence analysis allowing a constant flow of cells through microfluidic channels C. albicans orf19.3477 ORF CAL0005064 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient YNB medium C. albicans orf19.3478 ORF NIP7 CAL0005065 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.348 ORF SKN2 CAL0004802 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.348 ORF SKN2 CAL0004802 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.348 ORF SKN2 CAL0004802 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.348 ORF SKN2 CAL0004802 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.3480 ORF CAL0005082 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 invasive growth: decreased solid SLAD media C. albicans orf19.3481 ORF CAL0005084 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.3483 ORF CAL0005088 PMID: 21414038|CGD_REF: CAL0141808 homozygous diploid, classical genetics null BWP17 viable C. albicans orf19.3483 ORF CAL0005088 PMID: 21414038|CGD_REF: CAL0141808 homozygous diploid, classical genetics null BWP17 biofilm formation: normal C. albicans orf19.3483 ORF CAL0005088 PMID: 23572557|CGD_REF: CAL0000158900 homozygous diploid, classical genetics null BWP17 adhesion: decreased Fluxion Bioflux 200, equipped with a microscope, was used for adherence analysis allowing a constant flow of cells through microfluidic channels C. albicans orf19.349 ORF CAL0004805 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.3490 ORF FGR6-4 CAL0005112 PMID: 12773383|CGD_REF: CAL0087974 heterozygous diploid, classical genetics (haploinsufficient phenotype assay) unspecified CAI-4 filamentous growth: decreased solid Spider medium transposon insertion proximal to, but not within, the ORF C. albicans orf19.3496 ORF CHC1 CAL0005122 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.35 ORF CAL0000551 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.350 ORF PRE9 CAL0004819 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.3506 ORF DBR1 CAL0005778 PMID: 17351132|CGD_REF: CAL0117571 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.3506 ORF DBR1 CAL0005778 PMID: 17351132|CGD_REF: CAL0117571 homozygous diploid, classical genetics null Not recorded RNA accumulation: increased lariat splicing intermediates C. albicans orf19.3507 ORF MCR1 CAL0005780 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.3515 ORF CAL0005808 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 invasive growth: decreased solid SLAD media C. albicans orf19.3516 ORF CAL0005812 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient YPD medium C. albicans orf19.3516 ORF CAL0005812 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 invasive growth: decreased solid SLAD media C. albicans orf19.3519 ORF SUA72 CAL0005818 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient SC medium C. albicans orf19.3519 ORF SUA72 CAL0005818 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient SLAD medium C. albicans orf19.352 ORF CAL0004823 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient YPD medium C. albicans orf19.352 ORF CAL0004823 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient SC medium C. albicans orf19.352 ORF CAL0004823 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 invasive growth: decreased solid SLAD media C. albicans orf19.3523 ORF CRK1 CAL0005839 PMID: 12114968|CGD_REF: CAL0080854 homozygous diploid, classical genetics null Not recorded flocculation: increased C. albicans orf19.3523 ORF CRK1 CAL0005839 PMID: 12114968|CGD_REF: CAL0080854 homozygous diploid, classical genetics null Not recorded hyphal growth: abnormal Lee's liquid medium, ph 4.5 at 25 deg C grows hyphally while wild type is yeast-form under these conditions C. albicans orf19.3523 ORF CRK1 CAL0005839 PMID: 11073971|CGD_REF: CAL0080850 homozygous diploid, classical genetics null Not recorded hyphal growth: decreased solid M199, Spider, or serum-containing medium C. albicans orf19.3523 ORF CRK1 CAL0005839 PMID: 14507372|CGD_REF: CAL0088818 heterozygous diploid, large-scale survey (large-scale identification of essential genes by gene replacement and conditional expression (GRACE) method) repressible CAI-4 viable one allele is deleted and the other is placed under repressible Tet promoter C. albicans orf19.3523 ORF CRK1 CAL0005839 PMID: 11073971|CGD_REF: CAL0080850 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.3523 ORF CRK1 CAL0005839 PMID: 12114968|CGD_REF: CAL0080854 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.3523 ORF CRK1 CAL0005839 PMID: 11073971|CGD_REF: CAL0080850 homozygous diploid, classical genetics null Not recorded virulence: decreased mouse intravenous infection C. albicans orf19.3526 ORF ITR1 CAL0005849 PMID: 18268031|CGD_REF: CAL0118829 heterozygous diploid, classical genetics null Not recorded viable C. albicans orf19.3526 ORF ITR1 CAL0005849 PMID: 18268031|CGD_REF: CAL0118829 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.3526 ORF ITR1 CAL0005849 PMID: 18268031|CGD_REF: CAL0118829 heterozygous diploid, classical genetics null Not recorded small molecule transport: decreased myo-inositol C. albicans orf19.3526 ORF ITR1 CAL0005849 PMID: 18268031|CGD_REF: CAL0118829 heterozygous diploid, classical genetics null Not recorded virulence: normal mouse intravenous infection C. albicans orf19.3526 ORF ITR1 CAL0005849 PMID: 18268031|CGD_REF: CAL0118829 homozygous diploid, classical genetics null Not recorded virulence: normal mouse intravenous infection C. albicans orf19.3526 ORF ITR1 CAL0005849 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 invasive growth: decreased solid SLAD media C. albicans orf19.3527 ORF CYT1 CAL0005851 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.3530 ORF CKA2 CAL0005868 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.3530 ORF CKA2 CAL0005868 PMID: 14663094|CGD_REF: CAL0080633 homozygous diploid, systematic mutation set (homozygous insertion mutants generated with URA3-ARG4-URA3 (UAU1) cassette) null BWP17 viable C. albicans orf19.3530 ORF CKA2 CAL0005868 PMID: 15813744|CGD_REF: CAL0104042 heterozygous diploid, classical genetics null Not recorded viable C. albicans orf19.3530 ORF CKA2 CAL0005868 PMID: 16939537|CGD_REF: CAL0117180 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.3530 ORF CKA2 CAL0005868 PMID: 15813744|CGD_REF: CAL0104042 homozygous diploid, classical genetics null Not recorded resistance to chemicals: increased fluconazole phenotype is rescued by cyclosporin A, indicating involvement of the calcineurin pathway C. albicans orf19.3530 ORF CKA2 CAL0005868 PMID: 15813744|CGD_REF: CAL0104042 heterozygous diploid, classical genetics null Not recorded resistance to chemicals: normal fluconazole C. albicans orf19.3530 ORF CKA2 CAL0005868 PMID: 21407800|CGD_REF: CAL0141800 homozygous diploid, classical genetics null BWP17 interaction with host/environment: abnormal significantly reduced adhesion and damage to epithelial cells, but normal invasion ex vivo model of infection C. albicans orf19.3530 ORF CKA2 CAL0005868 PMID: 16939537|CGD_REF: CAL0117180 homozygous diploid, classical genetics null Not recorded virulence: decreased endothelial and oral epithelial cells decreased capacity to damage cells in vitro model of infection C. albicans orf19.3530 ORF CKA2 CAL0005868 PMID: 16939537|CGD_REF: CAL0117180 homozygous diploid, classical genetics null Not recorded virulence: normal mouse intravenous infection C. albicans orf19.3530 ORF CKA2 CAL0005868 PMID: 16939537|CGD_REF: CAL0117180 homozygous diploid, classical genetics null Not recorded virulence: decreased mouse oropharyngeal infection C. albicans orf19.3530 ORF CKA2 CAL0005868 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient YPD medium C. albicans orf19.3531 ORF CAL0005871 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.3532 ORF MRPL10 CAL0005873 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.3532 ORF MRPL10 CAL0005873 PMID: 21135205|CGD_REF: CAL0139967 heterozygous diploid, large-scale survey (large-scale identification of genes essential for virulence in mouse) repressible CAI-4 virulence: absent mouse intravenous infection C. albicans orf19.3534 ORF RHO3 CAL0005878 PMID: 17351079|CGD_REF: CAL0117784 heterozygous diploid, classical genetics repressible BWP17 hyphal growth: abnormal hyphal tips are swollen soon after germ tube formation C. albicans orf19.3534 ORF RHO3 CAL0005878 PMID: 17351079|CGD_REF: CAL0117784 heterozygous diploid, classical genetics repressible Not recorded cell shape: abnormal round cells C. albicans orf19.3534 ORF RHO3 CAL0005878 PMID: 17351079|CGD_REF: CAL0117784 homozygous diploid, classical genetics null Not recorded inviable homozygous null mutant strain could not be recovered, suggesting that the gene is essential under the selection conditions C. albicans orf19.3534 ORF RHO3 CAL0005878 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.3534 ORF RHO3 CAL0005878 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.3534 ORF RHO3 CAL0005878 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.3534 ORF RHO3 CAL0005878 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.3537 ORF CAL0005887 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient YPD medium C. albicans orf19.3539 ORF CAL0005891 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.354 ORF CAL0004826 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 invasive growth: decreased solid SLAD media C. albicans orf19.3540 ORF MAK5 CAL0005900 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.3540 ORF MAK5 CAL0005900 PMID: 21135205|CGD_REF: CAL0139967 heterozygous diploid, large-scale survey (large-scale identification of genes essential for virulence in mouse) repressible CAI-4 virulence: absent mouse intravenous infection C. albicans orf19.3541 ORF ERF1 CAL0005902 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.3542 ORF LEM3 CAL0005904 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.3542 ORF LEM3 CAL0005904 PMID: 16078083|CGD_REF: CAL0114544 heterozygous diploid, classical genetics null Not recorded viable C. albicans orf19.3542 ORF LEM3 CAL0005904 PMID: 16078083|CGD_REF: CAL0114544 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.3542 ORF LEM3 CAL0005904 PMID: 16078083|CGD_REF: CAL0114544 heterozygous diploid, classical genetics null Not recorded resistance to chemicals: increased miltefosine phenotype is intermediate between that of wild type and the homozygous null mutant C. albicans orf19.3542 ORF LEM3 CAL0005904 PMID: 16078083|CGD_REF: CAL0114544 homozygous diploid, classical genetics null Not recorded resistance to chemicals: increased miltefosine C. albicans orf19.3544 ORF CAL0005908 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.3545 ORF CAL0005910 PMID: 23856128|CGD_REF: CAL0000172540 homozygous diploid, classical genetics null BWP17 resistance to chemicals: decreased propolis C. albicans orf19.3546 ORF PEX2 CAL0005912 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.3548 ORF CAL0005914 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.3548.1 ORF WH11 CAF0006989 PMID: 15249973|CGD_REF: CAL0082100 homozygous diploid, classical genetics null Not recorded viable no apparent phenotype C. albicans orf19.3548.1 ORF WH11 CAF0006989 PMID: 9353021|CGD_REF: CAL0081614 unknown ploidy, classical genetics misexpression WO-1 phenotypic switching: increased opaque-to-white switching C. albicans orf19.3548.1 ORF WH11 CAF0006989 PMID: 9353021|CGD_REF: CAL0081614 unknown ploidy, classical genetics misexpression WO-1 virulence: increased increased kidney colonization; colonization by opaque cells due to increased opaque-to-white switching mouse intravenous infection C. albicans orf19.3548.1 ORF WH11 CAF0006989 PMID: 23563485|CGD_REF: CAL0000158903 homozygous diploid, classical genetics null a/alpha wh11::FRT/wh11::FRT SC5314 biofilm formation: abnormal RPMI medium 29 degrees C with rocking for 48 hr mutants have increased permeability to Sybro Ruby and PMN infiltration and decreased resistance to fluconaazole C. albicans orf19.3548.1 ORF WH11 CAF0006989 PMID: 23563485|CGD_REF: CAL0000158903 heterozygous diploid, classical genetics repressible a/a ADH1/adh1::pTET-WH11-GFP::SATR P37005 biofilm formation: abnormal RPMI medium 29 degrees C with rocking for 48 hr decreased Sypro Ruby and human PMN penetrability, decreased resistance to fluconazole C. albicans orf19.355 ORF CAL0004829 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.3551 ORF DAD2 CAL0005920 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.3551 ORF DAD2 CAL0005920 PMID: 21549601|CGD_REF: CAL0142005 heterozygous diploid, classical genetics repressible BWP17 inviable repressible conditions (with tetracycline) Gene replacement and conditional expression (GRACE) C. albicans orf19.3551 ORF DAD2 CAL0005920 PMID: 21571923|CGD_REF: CAL0142042 homozygous diploid, classical genetics repressible dad2::HIS1/PCK1(p)-DAD2 Other C. albicans inviable repressing conditions C. albicans orf19.3551 ORF DAD2 CAL0005920 PMID: 21571923|CGD_REF: CAL0142042 homozygous diploid, classical genetics repressible dad2::HIS1/PCK1(p)-DAD2 Other C. albicans cell cycle progression: arrested repressing conditions mutant accumulates large budded cells after 4h of growth under nonpermissive conditions, prolonged incubation leads to a transition to an elongated (pseudohyphal-like) bud C. albicans orf19.3551 ORF DAD2 CAL0005920 PMID: 21571923|CGD_REF: CAL0142042 homozygous diploid, classical genetics repressible dad2::HIS1/PCK1(p)-DAD2 Other C. albicans chromosome segregation: abnormal repressing conditions C. albicans orf19.3551 ORF DAD2 CAL0005920 PMID: 21135205|CGD_REF: CAL0139967 heterozygous diploid, competitive growth (large-scale identification of genes essential for virulence in mouse) repressible CAI-4 virulence: decreased mouse intravenous infection C. albicans orf19.3552 ORF CAL0005922 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.3553 ORF RPF2 CAL0005924 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, competitive growth (haploinsufficient phenotype assay, barcode deletion set) null SC5314 resistance to chemicals: decreased 5-fluorouracil C. albicans orf19.3553 ORF RPF2 CAL0005924 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, competitive growth (haploinsufficient phenotype assay, barcode deletion set) null SC5314 resistance to chemicals: decreased tubercidin C. albicans orf19.3553 ORF RPF2 CAL0005924 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, competitive growth (haploinsufficient phenotype assay, barcode deletion set) null SC5314 resistance to chemicals: decreased flucytosine C. albicans orf19.3553 ORF RPF2 CAL0005924 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.3553 ORF RPF2 CAL0005924 PMID: 21135205|CGD_REF: CAL0139967 heterozygous diploid, competitive growth (large-scale identification of genes essential for virulence in mouse) repressible CAI-4 virulence: decreased mouse intravenous infection C. albicans orf19.3554 ORF AAT1 CAL0005926 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.3555 ORF BUD14 CAL0005928 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.3555 ORF BUD14 CAL0005928 PMID: 20402797|CGD_REF: CAL0125391 homozygous diploid, classical genetics null Other C. albicans viable C. albicans orf19.3556 ORF CAL0005930 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.3556 ORF CAL0005930 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient YPD medium C. albicans orf19.3556 ORF CAL0005930 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient SLAD medium C. albicans orf19.3557 ORF GPI19 CAL0005931 PMID: 20576690|CGD_REF: CAL0125835 heterozygous diploid, classical genetics repressible gpi19/MET3-GFP-GPI19 BWP17 vegetative growth: decreased rate repressive conditions (10 mM Met/Cys) modest decrease in doubling time C. albicans orf19.3557 ORF GPI19 CAL0005931 PMID: 20576690|CGD_REF: CAL0125835 heterozygous diploid, classical genetics repressible gpi19/MET3-GFP-GPI19 BWP17 chitin deposition: abnormal repressive conditions (10 mM Met/Cys) uniform distribution over cell surface C. albicans orf19.3557 ORF GPI19 CAL0005931 PMID: 20576690|CGD_REF: CAL0125835 heterozygous diploid, classical genetics repressible gpi19/MET3-GFP-GPI19 BWP17 filamentous growth: increased repressive conditions, 10% serum or Spider medium (10 mM Met/Cys) C. albicans orf19.3557 ORF GPI19 CAL0005931 PMID: 20576690|CGD_REF: CAL0125835 heterozygous diploid, classical genetics repressible gpi19/MET3-GFP-GPI19 BWP17 resistance to chemicals: increased amphotericin B repressive conditions (10 mM Met/Cys) C. albicans orf19.3557 ORF GPI19 CAL0005931 PMID: 20576690|CGD_REF: CAL0125835 heterozygous diploid, classical genetics repressible gpi19/MET3-GFP-GPI19 BWP17 resistance to chemicals: decreased fluconazole repressive conditions (10 mM Met/Cys) C. albicans orf19.3557 ORF GPI19 CAL0005931 PMID: 20576690|CGD_REF: CAL0125835 heterozygous diploid, classical genetics repressible gpi19/MET3-GFP-GPI19 BWP17 resistance to chemicals: decreased miconazole repressive conditions (10 mM Met/Cys) C. albicans orf19.3557 ORF GPI19 CAL0005931 PMID: 20576690|CGD_REF: CAL0125835 heterozygous diploid, classical genetics repressible gpi19/MET3-GFP-GPI19 BWP17 resistance to chemicals: decreased ketoconazole repressive conditions (10 mM Met/Cys) C. albicans orf19.3557 ORF GPI19 CAL0005931 PMID: 20576690|CGD_REF: CAL0125835 heterozygous diploid, classical genetics null BWP17 resistance to chemicals: increased amphotericin B C. albicans orf19.3558 ORF CAL0005932 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.3561 ORF CDC7 CAL0005945 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.3563 ORF CAL0005948 PMID: 14663094|CGD_REF: CAL0080633 homozygous diploid, systematic mutation set (homozygous insertion mutants generated with URA3-ARG4-URA3 (UAU1) cassette) null BWP17 viable C. albicans orf19.3564 ORF RPC40 CAL0005950 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.3564 ORF RPC40 CAL0005950 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 invasive growth: decreased solid SLAD media C. albicans orf19.3565 ORF CAL0005952 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 invasive growth: decreased solid SLAD media C. albicans orf19.3567 ORF BIO32 CAL0005953 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.3568 ORF RXT3 CAL0005954 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient YPD medium C. albicans orf19.3568 ORF RXT3 CAL0005954 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient SC medium C. albicans orf19.3568 ORF RXT3 CAL0005954 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient SLAD medium C. albicans orf19.3568 ORF RXT3 CAL0005954 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 invasive growth: decreased solid SLAD media C. albicans orf19.357 ORF CAL0004834 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.3573 ORF PEX6 CAL0005974 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.3574 ORF MDJ2 CAL0005975 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.3574 ORF MDJ2 CAL0005975 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.3574 ORF MDJ2 CAL0005975 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.3574 ORF MDJ2 CAL0005975 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.3575 ORF CDC19 CAL0005977 PMID: 12773383|CGD_REF: CAL0087974 heterozygous diploid, classical genetics (haploinsufficient phenotype assay) null CAI-4 viable heterozygous transposon insertion C. albicans orf19.3575 ORF CDC19 CAL0005977 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.3575 ORF CDC19 CAL0005977 PMID: 12773383|CGD_REF: CAL0087974 heterozygous diploid, classical genetics (haploinsufficient phenotype assay) null CAI-4 filamentous growth: decreased solid Spider medium heterozygous transposon insertion C. albicans orf19.3575 ORF CDC19 CAL0005977 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: decreased growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.3575 ORF CDC19 CAL0005977 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.3575 ORF CDC19 CAL0005977 PMID: 16681837|CGD_REF: CAL0116091 homozygous diploid, classical genetics null Not recorded virulence: decreased mouse intravenous infection C. albicans orf19.3575 ORF CDC19 CAL0005977 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.3575 ORF CDC19 CAL0005977 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.3577 ORF COQ5 CAL0005978 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.3577 ORF COQ5 CAL0005978 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, competitive growth (haploinsufficient phenotype assay, barcode deletion set) null SC5314 resistance to chemicals: decreased ergosterol analogs (ECC69 and/or ECC1384) C. albicans orf19.3581 ORF CAL0005992 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.3585 ORF CAL0006000 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.3586 ORF CAL0006001 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.3589 ORF SPO11 CAL0006003 PMID: 18462019|CGD_REF: CAL0119081 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.3589 ORF SPO11 CAL0006003 PMID: 18462019|CGD_REF: CAL0119081 homozygous diploid, classical genetics null Not recorded mitotic recombination: absent during the parasexual cycle C. albicans orf19.3589 ORF SPO11 CAL0006003 PMID: 18462019|CGD_REF: CAL0119081 homozygous diploid, classical genetics null Not recorded mitotic recombination: absent during the parasexual cycle C. albicans orf19.3590 ORF IPP1 CAL0006016 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.3591 ORF APE3 CAL0006018 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.3592 ORF JEM1 CAL0006020 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.3592 ORF JEM1 CAL0006020 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.3592 ORF JEM1 CAL0006020 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.3592 ORF JEM1 CAL0006020 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.3592 ORF JEM1 CAL0006020 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.3593 ORF RPT6 CAL0006022 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.3599 ORF TIF4631 CAL0006026 PMID: 16212935|CGD_REF: CAL0114868 heterozygous diploid, classical genetics overexpression Not recorded viable C. albicans orf19.3601 ORF CAL0000272 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient SC medium C. albicans orf19.3603 ORF MFG1 CAL0000273 PMID: 22984072|CGD_REF: CAL0000157844 homozygous diploid, classical genetics null mfg1::FRT/mfg1::FRT SN95 viable C. albicans orf19.3603 ORF MFG1 CAL0000273 PMID: 22984072|CGD_REF: CAL0000157844 homozygous diploid, classical genetics null mfg1::FRT/mfg1::FRT SN95 filamentous growth: absent C. albicans orf19.3603 ORF MFG1 CAL0000273 PMID: 22984072|CGD_REF: CAL0000157844 homozygous diploid, classical genetics null mfg1::FRT/mfg1::FRT SN95 virulence: decreased insect infection (Galleria mellonella survival model) C. albicans orf19.3603 ORF MFG1 CAL0000273 PMID: 22984072|CGD_REF: CAL0000157844 homozygous diploid, classical genetics null mfg1::FRT/mfg1::FRT SN95 biofilm formation: decreased RPMI medium at 37 deg C. albicans orf19.3604 ORF CAL0000276 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient SLAD medium C. albicans orf19.3607 ORF CAL0000286 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.3609 ORF UTP15 CAL0000290 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, competitive growth (haploinsufficient phenotype assay, barcode deletion set) null SC5314 resistance to chemicals: increased flucytosine C. albicans orf19.3609 ORF UTP15 CAL0000290 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.3609 ORF UTP15 CAL0000290 PMID: 21135205|CGD_REF: CAL0139967 heterozygous diploid, competitive growth (large-scale identification of genes essential for virulence in mouse) repressible CAI-4 virulence: decreased mouse intravenous infection C. albicans orf19.3611 ORF CAL0000301 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: decreased growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.3611 ORF CAL0000301 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.3611 ORF CAL0000301 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: decreased rate liquid synthetic complete medium C. albicans orf19.3611 ORF CAL0000301 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.3613 ORF CAL0000306 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.3615 ORF CAL0000313 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.3615 ORF CAL0000313 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.3615 ORF CAL0000313 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.3615 ORF CAL0000313 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.3615 ORF CAL0000313 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.3616 ORF ERG9 CAL0000316 PMID: 12524333|CGD_REF: CAL0080691 homozygous diploid, systematic mutation set (homozygous insertion mutants generated with URA3-ARG4-URA3 (UAU1) cassette) null BWP17 inviable homozygous null mutant strain could not be recovered, suggesting that the gene is essential under the selection conditions C. albicans orf19.3616 ORF ERG9 CAL0000316 PMID: 21135205|CGD_REF: CAL0139967 heterozygous diploid, large-scale survey (large-scale identification of genes essential for virulence in mouse) repressible CAI-4 virulence: absent mouse intravenous infection C. albicans orf19.3617 ORF GTR1 CAL0000319 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.3617 ORF GTR1 CAL0000319 PMID: 22438810|CGD_REF: CAL0000156986 homozygous diploid, classical genetics null BWP17 viable C. albicans orf19.3618 ORF YWP1 CAL0000321 PMID: 15870471|CGD_REF: CAL0082509 heterozygous diploid, classical genetics null Not recorded viable C. albicans orf19.3618 ORF YWP1 CAL0000321 PMID: 15870471|CGD_REF: CAL0082509 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.3618 ORF YWP1 CAL0000321 PMID: 18765290|CGD_REF: CAL0119430 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.3618 ORF YWP1 CAL0000321 PMID: 15870471|CGD_REF: CAL0082509 heterozygous diploid, classical genetics null Not recorded adhesion: increased phenotype is intermediate between that of wild type and the homozygous null mutant C. albicans orf19.3618 ORF YWP1 CAL0000321 PMID: 15870471|CGD_REF: CAL0082509 homozygous diploid, classical genetics null Not recorded adhesion: increased adhesion to polystyrene C. albicans orf19.3618 ORF YWP1 CAL0000321 PMID: 19187560|CGD_REF: CAL0122338 homozygous diploid, classical genetics null SC5314 biofilm formation: abnormal forms biofilm with altered detachment properties C. albicans orf19.3618 ORF YWP1 CAL0000321 PMID: 21414038|CGD_REF: CAL0141808 homozygous diploid, classical genetics null BWP17 viable C. albicans orf19.3618 ORF YWP1 CAL0000321 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.3618 ORF YWP1 CAL0000321 PMID: 21414038|CGD_REF: CAL0141808 homozygous diploid, classical genetics null BWP17 biofilm formation: normal C. albicans orf19.3618 ORF YWP1 CAL0000321 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.3618 ORF YWP1 CAL0000321 PMID: 15870471|CGD_REF: CAL0082509 homozygous diploid, classical genetics null BWP17 biofilm formation: abnormal on polystyrene increased biofilm thickness C. albicans orf19.3618 ORF YWP1 CAL0000321 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.3618 ORF YWP1 CAL0000321 PMID: 15870471|CGD_REF: CAL0082509 homozygous diploid, classical genetics null Not recorded virulence: normal mouse intravenous infection C. albicans orf19.3618 ORF YWP1 CAL0000321 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.3621 ORF CAL0000334 PMID: 15870471|CGD_REF: CAL0082509 homozygous diploid, classical genetics null BWP17 viable no apparent phenotype C. albicans orf19.3623 ORF SMC2 CAL0000340 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.3625 ORF CAL0000348 PMID: 23526879|CGD_REF: CAL0000158852 homozygous diploid, classical genetics null SN152 viable C. albicans orf19.3625 ORF CAL0000348 PMID: 23526879|CGD_REF: CAL0000158852 homozygous diploid, classical genetics null SN152 virulence: decreased significant defect in GI tract colonization mouse gastrointestinal tract infection C. albicans orf19.3626 ORF CAL0000351 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.3628 ORF RSP5 CAL0000356 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.3628 ORF RSP5 CAL0000356 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 invasive growth: decreased solid SLAD media C. albicans orf19.3629 ORF DSE1 CAL0000357 PMID: 21760783|CGD_REF: CAL0000142509 heterozygous diploid, classical genetics null RM1000 filamentous growth: increased increase in filamentation of the mutant compared to the wild type C. albicans orf19.3629 ORF DSE1 CAL0000357 PMID: 21760783|CGD_REF: CAL0000142509 homozygous diploid, classical genetics null RM1000 inviable unable to obtain homozygous null mutants under the conditions used C. albicans orf19.3629 ORF DSE1 CAL0000357 PMID: 21760783|CGD_REF: CAL0000142509 heterozygous diploid, classical genetics null RM1000 invasive growth: increased increase in invasiveness of the mutant compared to the wild type C. albicans orf19.3629 ORF DSE1 CAL0000357 PMID: 21760783|CGD_REF: CAL0000142509 heterozygous diploid, classical genetics null RM1000 resistance to chemicals: decreased Calcofluor White C. albicans orf19.3629 ORF DSE1 CAL0000357 PMID: 21760783|CGD_REF: CAL0000142509 heterozygous diploid, classical genetics null RM1000 chitin deposition: decreased mutant chitin content was 84% that of the wild type C. albicans orf19.3629 ORF DSE1 CAL0000357 PMID: 21760783|CGD_REF: CAL0000142509 heterozygous diploid, classical genetics null RM1000 resistance to chemicals: decreased hydrogen peroxide C. albicans orf19.3629 ORF DSE1 CAL0000357 PMID: 21760783|CGD_REF: CAL0000142509 heterozygous diploid, classical genetics null RM1000 biofilm formation: decreased mutants display a 30% reduction in biofilm formation C. albicans orf19.3629 ORF DSE1 CAL0000357 PMID: 21760783|CGD_REF: CAL0000142509 heterozygous diploid, classical genetics null RM1000 virulence: decreased mouse intravenous infection C. albicans orf19.3629 ORF DSE1 CAL0000357 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 invasive growth: decreased solid SLAD media C. albicans orf19.3630 ORF RRP8 CAL0000367 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.3631 ORF STN1 CAL0000369 PMID: 20008938|CGD_REF: CAL0124723 homozygous diploid, classical genetics null BWP17 viable C. albicans orf19.3631 ORF STN1 CAL0000369 PMID: 20008938|CGD_REF: CAL0124723 homozygous diploid, classical genetics null BWP17 vegetative growth: decreased rate C. albicans orf19.3631 ORF STN1 CAL0000369 PMID: 20008938|CGD_REF: CAL0124723 homozygous diploid, classical genetics null BWP17 filamentous growth: increased increased abundance of filamentous cells in liquid cultures C. albicans orf19.3631 ORF STN1 CAL0000369 PMID: 20008938|CGD_REF: CAL0124723 homozygous diploid, classical genetics null BWP17 telomere length: increased extremely long and heterogeneous telomeres C. albicans orf19.3638 ORF PGA46 CAL0000386 PMID: 18765290|CGD_REF: CAL0119430 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.3639 ORF CAL0000388 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.3642 ORF SUN41 CAL0000399 PMID: 17905924|CGD_REF: CAL0118686 homozygous diploid, classical genetics null Not recorded resistance to chemicals: normal Calcofluor White C. albicans orf19.3642 ORF SUN41 CAL0000399 PMID: 18001349|CGD_REF: CAL0118752 homozygous diploid, classical genetics null Not recorded germ tube formation: abnormal germ tube elongation is impaired C. albicans orf19.3642 ORF SUN41 CAL0000399 PMID: 17555439|CGD_REF: CAL0117968 homozygous diploid, classical genetics null Not recorded survival rate in stationary phase: decreased C. albicans orf19.3642 ORF SUN41 CAL0000399 PMID: 17905924|CGD_REF: CAL0118686 homozygous diploid, classical genetics null SC5314 hyphal growth: decreased solid medium C. albicans orf19.3642 ORF SUN41 CAL0000399 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.3642 ORF SUN41 CAL0000399 PMID: 17873081|CGD_REF: CAL0118685 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.3642 ORF SUN41 CAL0000399 PMID: 17905924|CGD_REF: CAL0118686 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.3642 ORF SUN41 CAL0000399 PMID: 17905924|CGD_REF: CAL0118686 homozygous diploid, classical genetics null Not recorded adhesion: decreased adhesion to Caco-2 cell monolayer C. albicans orf19.3642 ORF SUN41 CAL0000399 PMID: 17905924|CGD_REF: CAL0118686 homozygous diploid, classical genetics null Not recorded cell size: increased C. albicans orf19.3642 ORF SUN41 CAL0000399 PMID: 18001349|CGD_REF: CAL0118752 homozygous diploid, classical genetics null Not recorded cytokinesis: absent chains of cells observed C. albicans orf19.3642 ORF SUN41 CAL0000399 PMID: 17905924|CGD_REF: CAL0118686 homozygous diploid, classical genetics null Not recorded cytokinesis: absent C. albicans orf19.3642 ORF SUN41 CAL0000399 PMID: 17905924|CGD_REF: CAL0118686 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased Congo Red C. albicans orf19.3642 ORF SUN41 CAL0000399 PMID: 17873081|CGD_REF: CAL0118685 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased caspofungin C. albicans orf19.3642 ORF SUN41 CAL0000399 PMID: 21820070|CGD_REF: CAL0000142790 homozygous diploid, classical genetics null Other C. albicans biofilm formation: decreased mildly defective in biofilm formation in vivo C. albicans orf19.3642 ORF SUN41 CAL0000399 PMID: 17873081|CGD_REF: CAL0118685 homozygous diploid, classical genetics null BWP17 biofilm formation: abnormal C. albicans orf19.3642 ORF SUN41 CAL0000399 PMID: 17905924|CGD_REF: CAL0118686 homozygous diploid, classical genetics null SC5314 biofilm formation: decreased C. albicans orf19.3642 ORF SUN41 CAL0000399 PMID: 17873081|CGD_REF: CAL0118685 homozygous diploid, classical genetics null Not recorded virulence: decreased mouse intravenous infection C. albicans orf19.3642 ORF SUN41 CAL0000399 PMID: 17873081|CGD_REF: CAL0118685 homozygous diploid, classical genetics null Not recorded virulence: decreased mouse oropharyngeal infection C. albicans orf19.3643 ORF CAL0000401 PMID: 20494978|CGD_REF: CAL0125636 heterozygous diploid, classical genetics null BWP17 resistance to chemicals: decreased clotrimazole (75 uM) growth in liquid culture confirmation of mutant phenotypes for heterozygous transposon insertion strains showing sensitivity in a large-scale assay C. albicans orf19.3646 ORF CTR1 CAL0000406 PMID: 12777486|CGD_REF: CAL0081092 homozygous diploid, classical genetics null Not recorded respiratory growth: absent defect is rescued by exogenous copper C. albicans orf19.3646 ORF CTR1 CAL0000406 PMID: 12777486|CGD_REF: CAL0081092 homozygous diploid, classical genetics null BWP17 hyphal growth: normal liquid YPD plus serum C. albicans orf19.3646 ORF CTR1 CAL0000406 PMID: 15256562|CGD_REF: CAL0082101 homozygous diploid, classical genetics null Not recorded utilization of iron source: decreased decreased iron uptake C. albicans orf19.3646 ORF CTR1 CAL0000406 PMID: 12777486|CGD_REF: CAL0081092 homozygous diploid, classical genetics null Not recorded vegetative growth: decreased rate growth defect is rescued by exogenous copper C. albicans orf19.3646 ORF CTR1 CAL0000406 PMID: 12777486|CGD_REF: CAL0081092 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.3646 ORF CTR1 CAL0000406 PMID: 15256562|CGD_REF: CAL0082101 homozygous diploid, classical genetics null BWP17 invasive growth: increased increased agar-invasive growth, consistent with a defect in copper acquisition C. albicans orf19.3646 ORF CTR1 CAL0000406 PMID: 12777486|CGD_REF: CAL0081092 homozygous diploid, classical genetics null Not recorded oxidative stress resistance: decreased hydrogen peroxide sensitivity is rescued by exogenous copper C. albicans orf19.3646 ORF CTR1 CAL0000406 PMID: 12777486|CGD_REF: CAL0081092 homozygous diploid, classical genetics null Not recorded cellular morphology: abnormal defect is rescued by exogenous copper C. albicans orf19.3646 ORF CTR1 CAL0000406 PMID: 12777486|CGD_REF: CAL0081092 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased oxytetracycline C. albicans orf19.3646 ORF CTR1 CAL0000406 PMID: 12777486|CGD_REF: CAL0081092 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased iron chelators sensitivity is rescued by exogenous copper C. albicans orf19.3647 ORF SEC8 CAL0000407 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.3647 ORF SEC8 CAL0000407 PMID: 20494978|CGD_REF: CAL0125636 heterozygous diploid, classical genetics null BWP17 resistance to chemicals: decreased clotrimazole (75 uM) growth in liquid culture confirmation of mutant phenotypes for heterozygous transposon insertion strains showing sensitivity in a large-scale assay C. albicans orf19.3649 ORF CAL0000409 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.3651 ORF PGK1 CAL0000415 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.3653 ORF FAT1 CAL0000418 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient YNB medium C. albicans orf19.3656 ORF COX15 CAL0000422 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.3656 ORF COX15 CAL0000422 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 invasive growth: decreased solid SLAD media C. albicans orf19.3658 ORF CAL0000424 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.3665 ORF SET6 CAL0000436 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.3665 ORF SET6 CAL0000436 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.3665 ORF SET6 CAL0000436 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.3665 ORF SET6 CAL0000436 PMID: 23572557|CGD_REF: CAL0000158900 homozygous diploid, classical genetics null BWP17 adhesion: increased Fluxion Bioflux 200, equipped with a microscope, was used for adherence analysis allowing a constant flow of cells through microfluidic channels C. albicans orf19.3665 ORF SET6 CAL0000436 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.3666 ORF CAL0000437 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.3667 ORF CAL0000438 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.3667 ORF CAL0000438 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.3667 ORF CAL0000438 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.3667 ORF CAL0000438 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.3667 ORF CAL0000438 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.3669 ORF SHA3 CAL0000440 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.3669 ORF SHA3 CAL0000440 PMID: 14507372|CGD_REF: CAL0088818 heterozygous diploid, large-scale survey (large-scale identification of essential genes by gene replacement and conditional expression (GRACE) method) repressible CAI-4 viable one allele is deleted and the other is placed under repressible Tet promoter C. albicans orf19.3669 ORF SHA3 CAL0000440 PMID: 12773383|CGD_REF: CAL0087974 heterozygous diploid, classical genetics (haploinsufficient phenotype assay) unspecified CAI-4 filamentous growth: decreased solid Spider medium transposon insertion proximal to, but not within, the ORF C. albicans orf19.3669 ORF SHA3 CAL0000440 PMID: 24603354|CGD_REF: CAL0000173791 heterozygous diploid, classical genetics null BWP17 colony appearance: abnormal Spider growth medium with mannitol less wrinkled colonies C. albicans orf19.3669 ORF SHA3 CAL0000440 PMID: 24603354|CGD_REF: CAL0000173791 heterozygous diploid, classical genetics null BWP17 biofilm formation: decreased Spider growth medium with mannitol C. albicans orf19.367 ORF CNH1 CAL0004864 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.367 ORF CNH1 CAL0004864 PMID: 14507372|CGD_REF: CAL0088818 heterozygous diploid, large-scale survey (large-scale identification of essential genes by gene replacement and conditional expression (GRACE) method) repressible CAI-4 viable one allele is deleted and the other is placed under repressible Tet promoter C. albicans orf19.367 ORF CNH1 CAL0004864 PMID: 10832630|CGD_REF: CAL0081045 heterozygous diploid, classical genetics null CNH1/cnh1::hisG?URA3?hisG CAI-4 colony appearance: normal sodium C. albicans orf19.367 ORF CNH1 CAL0004864 PMID: 10832630|CGD_REF: CAL0081045 heterozygous diploid, classical genetics null CNH1/cnh1::hisG?URA3?hisG CAI-4 metal resistance: normal lithium C. albicans orf19.367 ORF CNH1 CAL0004864 PMID: 10832630|CGD_REF: CAL0081045 heterozygous diploid, classical genetics null CNH1/cnh1::hisG?URA3?hisG CAI-4 metal resistance: normal C. albicans orf19.367 ORF CNH1 CAL0004864 PMID: 10832630|CGD_REF: CAL0081045 heterozygous diploid, classical genetics null CNH1/cnh1::hisG?URA3?hisG CAI-4 vegetative growth: decreased rate slow growth, intermediate phenotype C. albicans orf19.367 ORF CNH1 CAL0004864 PMID: 10832630|CGD_REF: CAL0081045 heterozygous diploid, classical genetics null CNH1/cnh1::hisG?URA3?hisG CAI-4 viable C. albicans orf19.367 ORF CNH1 CAL0004864 PMID: 10832630|CGD_REF: CAL0081045 heterozygous diploid, classical genetics null CNH1/cnh1::hisG?URA3?hisG CAI-4 virulence: normal mouse intravenous infection C. albicans orf19.367 ORF CNH1 CAL0004864 PMID: 10832630|CGD_REF: CAL0081045 homozygous diploid, classical genetics null cnh1::hisG/cnh1::hisG?URA3?hisG CAI-4 metal resistance: normal sodium C. albicans orf19.367 ORF CNH1 CAL0004864 PMID: 10832630|CGD_REF: CAL0081045 homozygous diploid, classical genetics null cnh1::hisG/cnh1::hisG?URA3?hisG CAI-4 metal resistance: normal lithium C. albicans orf19.367 ORF CNH1 CAL0004864 PMID: 10832630|CGD_REF: CAL0081045 homozygous diploid, classical genetics null cnh1::hisG/cnh1::hisG?URA3?hisG CAI-4 cell shape: abnormal solid YPD, liquid GMM at ph 5.5 or 7.5 elongated cells C. albicans orf19.367 ORF CNH1 CAL0004864 PMID: 10832630|CGD_REF: CAL0081045 homozygous diploid, classical genetics null cnh1::hisG/cnh1::hisG?URA3?hisG CAI-4 hyphal growth: normal liquid GMM plus serum or Lee's media C. albicans orf19.367 ORF CNH1 CAL0004864 PMID: 10832630|CGD_REF: CAL0081045 homozygous diploid, classical genetics null cnh1::hisG/cnh1::hisG?URA3?hisG CAI-4 vegetative growth: decreased rate C. albicans orf19.367 ORF CNH1 CAL0004864 PMID: 10832630|CGD_REF: CAL0081045 homozygous diploid, classical genetics null cnh1::hisG/cnh1::hisG?URA3?hisG CAI-4 viable C. albicans orf19.367 ORF CNH1 CAL0004864 PMID: 10832630|CGD_REF: CAL0081045 homozygous diploid, classical genetics null cnh1::hisG/cnh1::hisG?URA3?hisG CAI-4 virulence: decreased wild-type kidney colonization mouse intravenous infection C. albicans orf19.367 ORF CNH1 CAL0004864 PMID: 17660424|CGD_REF: CAL0118169 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased potassium(1+) low pH C. albicans orf19.367 ORF CNH1 CAL0004864 PMID: 17660424|CGD_REF: CAL0118169 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased potassium(1+) low pH C. albicans orf19.3670 ORF GAL1 CAL0000446 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.3670 ORF GAL1 CAL0000446 PMID: 1936958|CGD_REF: CAL0081320 unknown ploidy, classical genetics unspecified Other C. albicans resistance to chemicals: increased 2-deoxy-D-galactose C. albicans orf19.3670 ORF GAL1 CAL0000446 PMID: 1563045|CGD_REF: CAL0090736 unknown ploidy, classical genetics unspecified Other C. albicans resistance to chemicals: increased 2-deoxy-D-galactose increased resistance to 2-deoxy-galactose (2-DG); presumed gal1 mutations C. albicans orf19.3670 ORF GAL1 CAL0000446 PMID: 1563045|CGD_REF: CAL0090736 unknown ploidy, classical genetics unspecified Other C. albicans utilization of carbon source: abnormal defect in utilization of galactose carbon source; presumed gal1 mutations C. albicans orf19.3670 ORF GAL1 CAL0000446 PMID: 1563045|CGD_REF: CAL0090736 unknown ploidy, classical genetics unspecified Other C. albicans viable presumed gal1 mutations C. albicans orf19.3670 ORF GAL1 CAL0000446 PMID: 1563045|CGD_REF: CAL0090736 unknown ploidy, classical genetics unspecified CAI-4 viable C. albicans orf19.3670 ORF GAL1 CAL0000446 PMID: 12742062|CGD_REF: CAL0081329 homozygous diploid, classical genetics null CAI-4 viable C. albicans orf19.3670 ORF GAL1 CAL0000446 PMID: 12742062|CGD_REF: CAL0081329 homozygous diploid, classical genetics null RM1000 virulence: normal C. albicans orf19.3672 ORF GAL10 CAL0000448 PMID: 17178245|CGD_REF: CAL0117840 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased Calcofluor White C. albicans orf19.3672 ORF GAL10 CAL0000448 PMID: 17178245|CGD_REF: CAL0117840 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased sodium dodecyl sulfate C. albicans orf19.3672 ORF GAL10 CAL0000448 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.3672 ORF GAL10 CAL0000448 PMID: 17178245|CGD_REF: CAL0117840 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.3672 ORF GAL10 CAL0000448 PMID: 17178245|CGD_REF: CAL0117840 homozygous diploid, classical genetics null Not recorded oxidative stress resistance: decreased hydrogen peroxide C. albicans orf19.3672 ORF GAL10 CAL0000448 PMID: 17178245|CGD_REF: CAL0117840 homozygous diploid, classical genetics null Not recorded utilization of carbon source: absent galactose C. albicans orf19.3672 ORF GAL10 CAL0000448 PMID: 17178245|CGD_REF: CAL0117840 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased Congo Red C. albicans orf19.3672 ORF GAL10 CAL0000448 PMID: 17178245|CGD_REF: CAL0117840 homozygous diploid, classical genetics null BWP17 filamentous growth: increased filamentation-inducing conditions C. albicans orf19.3672 ORF GAL10 CAL0000448 PMID: 17178245|CGD_REF: CAL0117840 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased Hygromycin B C. albicans orf19.3672 ORF GAL10 CAL0000448 PMID: 17178245|CGD_REF: CAL0117840 homozygous diploid, classical genetics null BWP17 biofilm formation: abnormal forms biofilm almost entirely composed of filamentous cells C. albicans orf19.3673 ORF CAL0000449 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.3673 ORF CAL0000449 PMID: 21135205|CGD_REF: CAL0139967 heterozygous diploid, large-scale survey (large-scale identification of genes essential for virulence in mouse) repressible CAI-4 virulence: absent mouse intravenous infection C. albicans orf19.3674 ORF GAL102 CAL0000450 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.3674 ORF GAL102 CAL0000450 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, competitive growth (haploinsufficient phenotype assay, barcode deletion set) null SC5314 resistance to chemicals: decreased ergosterol analogs (ECC69 and/or ECC1384) C. albicans orf19.3674 ORF GAL102 CAL0000450 PMID: 22114559|CGD_REF: CAL0000143663 homozygous diploid, classical genetics null SC5314 viable C. albicans orf19.3674 ORF GAL102 CAL0000450 PMID: 22114559|CGD_REF: CAL0000143663 homozygous diploid, classical genetics null SC5314 resistance to chemicals: decreased Calcofluor White C. albicans orf19.3674 ORF GAL102 CAL0000450 PMID: 22114559|CGD_REF: CAL0000143663 homozygous diploid, classical genetics null Other C. albicans resistance to chemicals: decreased sodium dodecyl sulfate C. albicans orf19.3674 ORF GAL102 CAL0000450 PMID: 22114559|CGD_REF: CAL0000143663 homozygous diploid, classical genetics null Other C. albicans resistance to chemicals: decreased Congo Red C. albicans orf19.3674 ORF GAL102 CAL0000450 PMID: 22114559|CGD_REF: CAL0000143663 homozygous diploid, classical genetics null Other C. albicans resistance to chemicals: decreased echinocandin C. albicans orf19.3674 ORF GAL102 CAL0000450 PMID: 22114559|CGD_REF: CAL0000143663 homozygous diploid, classical genetics null Other C. albicans biofilm formation: abnormal C. albicans orf19.3674 ORF GAL102 CAL0000450 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 invasive growth: decreased solid SLAD media C. albicans orf19.3675 ORF GAL7 CAL0000451 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.3676 ORF ABP140 CAL0000452 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.3678 ORF CAL0000454 PMID: 14663094|CGD_REF: CAL0080633 homozygous diploid, systematic mutation set (homozygous insertion mutants generated with URA3-ARG4-URA3 (UAU1) cassette) null BWP17 viable C. albicans orf19.3679 ORF CAL0000455 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.3680 ORF SEP7 CAL0000463 PMID: 18234840|CGD_REF: CAL0118880 homozygous diploid, classical genetics null BWP17 hyphal growth: abnormal cell separation occurs during hyphal growth C. albicans orf19.3680 ORF SEP7 CAL0000463 PMID: 12819094|CGD_REF: CAL0080843 homozygous diploid, classical genetics null BWP17 hyphal growth: normal within macrophages normal hyphal growth upon engulfment by macrophage C. albicans orf19.3680 ORF SEP7 CAL0000463 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.3680 ORF SEP7 CAL0000463 PMID: 12181342|CGD_REF: CAL0080842 homozygous diploid, classical genetics null Not recorded viable no apparent phenotype C. albicans orf19.3680 ORF SEP7 CAL0000463 PMID: 12819094|CGD_REF: CAL0080843 heterozygous diploid, classical genetics null Not recorded viable C. albicans orf19.3680 ORF SEP7 CAL0000463 PMID: 12819094|CGD_REF: CAL0080843 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.3680 ORF SEP7 CAL0000463 PMID: 12819094|CGD_REF: CAL0080843 homozygous diploid, classical genetics null BWP17 invasive growth: decreased solid serum-containing medium slight decrease C. albicans orf19.3680 ORF SEP7 CAL0000463 PMID: 16002645|CGD_REF: CAL0114398 homozygous diploid, classical genetics null Not recorded chlamydospore formation: normal C. albicans orf19.3680 ORF SEP7 CAL0000463 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.3680 ORF SEP7 CAL0000463 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.3680 ORF SEP7 CAL0000463 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.3680 ORF SEP7 CAL0000463 PMID: 12819094|CGD_REF: CAL0080843 homozygous diploid, classical genetics null Not recorded virulence: normal mouse intravenous infection C. albicans orf19.3680 ORF SEP7 CAL0000463 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.3681 ORF CAL0000464 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.3682 ORF CWH8 CAL0000465 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.3683 ORF AGE3 CAL0000466 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.3683 ORF AGE3 CAL0000466 PMID: 15964282|CGD_REF: CAL0114274 homozygous diploid, systematic mutation set (split-marker transposon insertion strategy to disrupt both alleles) null BWP17 viable C. albicans orf19.3683 ORF AGE3 CAL0000466 PMID: 20140196|CGD_REF: CAL0124941 homozygous diploid, classical genetics null SN95 viable C. albicans orf19.3683 ORF AGE3 CAL0000466 PMID: 20140196|CGD_REF: CAL0124941 homozygous diploid, classical genetics null SN95 virulence: decreased mouse intravenous infection C. albicans orf19.3683 ORF AGE3 CAL0000466 PMID: 20140196|CGD_REF: CAL0124941 homozygous diploid, classical genetics null SN95 resistance to chemicals: decreased hygromycin B (80 micrograms/ml) C. albicans orf19.3683 ORF AGE3 CAL0000466 PMID: 20140196|CGD_REF: CAL0124941 homozygous diploid, classical genetics null SN95 resistance to chemicals: decreased caspofungin (150 micrograms/ml) C. albicans orf19.3683 ORF AGE3 CAL0000466 PMID: 20140196|CGD_REF: CAL0124941 homozygous diploid, classical genetics null SN95 resistance to chemicals: decreased fluconazole (10 micrograms/ml) C. albicans orf19.3683 ORF AGE3 CAL0000466 PMID: 20140196|CGD_REF: CAL0124941 homozygous diploid, classical genetics null SN95 resistance to chemicals: decreased Calcofluor White (22 micrograms/ml) C. albicans orf19.3683 ORF AGE3 CAL0000466 PMID: 15964282|CGD_REF: CAL0114274 homozygous diploid, systematic mutation set (split-marker transposon insertion strategy to disrupt both alleles) null BWP17 biofilm formation: normal C. albicans orf19.3683 ORF AGE3 CAL0000466 PMID: 20700541|CGD_REF: CAL0126030 homozygous diploid, classical genetics null SN87 endocytosis: delayed C. albicans orf19.3683 ORF AGE3 CAL0000466 PMID: 20700541|CGD_REF: CAL0126030 homozygous diploid, classical genetics null SN87 viable C. albicans orf19.3683 ORF AGE3 CAL0000466 PMID: 20700541|CGD_REF: CAL0126030 heterozygous diploid, classical genetics null SN87 viable C. albicans orf19.3683 ORF AGE3 CAL0000466 PMID: 20700541|CGD_REF: CAL0126030 homozygous diploid, classical genetics null SN87 hyphal growth: abnormal serum-containing liquid medium (defects also observed in various liquid and solid media) abnormal hyphal morphology, with many curved or spiral germ tubes and filaments C. albicans orf19.3683 ORF AGE3 CAL0000466 PMID: 20700541|CGD_REF: CAL0126030 homozygous diploid, classical genetics null SN87 invasive growth: abnormal solid Spider medium filaments are short and colonies are easily washed off the plate C. albicans orf19.3683 ORF AGE3 CAL0000466 PMID: 20700541|CGD_REF: CAL0126030 homozygous diploid, classical genetics null SN87 actin cytoskeleton morphology: abnormal actin patches are not concentrated at hyphal and germ tube tips C. albicans orf19.3683 ORF AGE3 CAL0000466 PMID: 20700541|CGD_REF: CAL0126030 homozygous diploid, classical genetics null SN87 resistance to chemicals: decreased hygromycin B (100 ug/ml) C. albicans orf19.3683 ORF AGE3 CAL0000466 PMID: 20700541|CGD_REF: CAL0126030 homozygous diploid, classical genetics null SN87 resistance to chemicals: decreased miconazole (20 ng/ml) C. albicans orf19.3683 ORF AGE3 CAL0000466 PMID: 20700541|CGD_REF: CAL0126030 homozygous diploid, classical genetics null SN87 resistance to chemicals: decreased itraconazole (10 ng/ml) C. albicans orf19.3683 ORF AGE3 CAL0000466 PMID: 20700541|CGD_REF: CAL0126030 homozygous diploid, classical genetics null SN87 resistance to chemicals: decreased cadmium(2+) (30 uM) C. albicans orf19.3683 ORF AGE3 CAL0000466 PMID: 20700541|CGD_REF: CAL0126030 homozygous diploid, classical genetics null SN87 resistance to chemicals: decreased sodium dodecyl sulfate (200 ug/ml) C. albicans orf19.3683 ORF AGE3 CAL0000466 PMID: 20700541|CGD_REF: CAL0126030 homozygous diploid, classical genetics null SN87 resistance to chemicals: decreased brefeldin A (40 uM) C. albicans orf19.3683 ORF AGE3 CAL0000466 PMID: 20700541|CGD_REF: CAL0126030 homozygous diploid, classical genetics null SN87 resistance to enzymatic treatment: increased zymolyase (20 ug/ml) C. albicans orf19.3685 ORF PSY2 CAL0000468 PMID: 21890819|CGD_REF: CAL0000142895 homozygous diploid, classical genetics null psy2::ARG4/psy2::HIS1 BWP17 viable C. albicans orf19.3685 ORF PSY2 CAL0000468 PMID: 21890819|CGD_REF: CAL0000142895 homozygous diploid, classical genetics null psy2::ARG4/psy2::HIS1 BWP17 resistance to chemicals: decreased methyl methanesulfonate C. albicans orf19.3685 ORF PSY2 CAL0000468 PMID: 21890819|CGD_REF: CAL0000142895 homozygous diploid, classical genetics null psy2::ARG4/psy2::HIS1 BWP17 resistance to chemicals: decreased cisplatin C. albicans orf19.3685 ORF PSY2 CAL0000468 PMID: 21890819|CGD_REF: CAL0000142895 homozygous diploid, classical genetics null psy2::ARG4/psy2::HIS1 BWP17 UV resistance: decreased C. albicans orf19.3685 ORF PSY2 CAL0000468 PMID: 22606354|CGD_REF: CAL0000157313 homozygous diploid, classical genetics null BWP17 protein/peptide modification: increased mutant displays Rad53 hyperphosphorylation Rad53 C. albicans orf19.3686 ORF CAL0000469 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.3689 ORF CAL0000472 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.3693 ORF PGA5 CAL0000485 PMID: 18765290|CGD_REF: CAL0119430 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.3693 ORF PGA5 CAL0000485 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.3693 ORF PGA5 CAL0000485 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.3693 ORF PGA5 CAL0000485 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.3693 ORF PGA5 CAL0000485 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.3695 ORF CAL0000487 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.3696 ORF TOM22 CAL0000488 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.3699 ORF TEP1 CAL0000491 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.3699 ORF TEP1 CAL0000491 PMID: 18708562|CGD_REF: CAL0119375 heterozygous diploid, classical genetics null Not recorded viable C. albicans orf19.3700 ORF TOM70 CAL0001055 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.3701 ORF CAL0001057 PMID: 14663094|CGD_REF: CAL0080633 homozygous diploid, systematic mutation set (homozygous insertion mutants generated with URA3-ARG4-URA3 (UAU1) cassette) null BWP17 viable C. albicans orf19.3704 ORF CAL0001062 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.3704.1 ORF CAF0006993 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient YNB medium C. albicans orf19.3705 ORF PTC6 CAL0001065 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.3705 ORF PTC6 CAL0001065 PMID: 18708562|CGD_REF: CAL0119375 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.3705 ORF PTC6 CAL0001065 PMID: 20033882|CGD_REF: CAL0124851 homozygous diploid, classical genetics null ptc6::hisG-URA3-hisG RM1000 viable no growth defects under many tested conditions: rapamycin, caffeine, cell wall affecting drugs, azole drugs, various carbon sources C. albicans orf19.3705 ORF PTC6 CAL0001065 PMID: 18708562|CGD_REF: CAL0119375 homozygous diploid, classical genetics null Not recorded virulence: decreased insect infection C. albicans orf19.3707 ORF YHB1 CAL0001071 PMID: 14663094|CGD_REF: CAL0080633 homozygous diploid, systematic mutation set (homozygous insertion mutants generated with URA3-ARG4-URA3 (UAU1) cassette) null BWP17 viable C. albicans orf19.3707 ORF YHB1 CAL0001071 PMID: 15189992|CGD_REF: CAL0082041 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.3707 ORF YHB1 CAL0001071 PMID: 15855504|CGD_REF: CAL0104062 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased nitrosyl sensitivity is not enhanced by econazole, which inhibits enzyme activity in vitro C. albicans orf19.3707 ORF YHB1 CAL0001071 PMID: 15189992|CGD_REF: CAL0082041 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased nitrosyl C. albicans orf19.3707 ORF YHB1 CAL0001071 PMID: 16030247|CGD_REF: CAL0114765 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased nitrosyl C. albicans orf19.3707 ORF YHB1 CAL0001071 PMID: 16030247|CGD_REF: CAL0114765 homozygous diploid, classical genetics null RM1000 filamentous growth: abnormal C. albicans orf19.3707 ORF YHB1 CAL0001071 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.3707 ORF YHB1 CAL0001071 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.3707 ORF YHB1 CAL0001071 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.3707 ORF YHB1 CAL0001071 PMID: 23285201|CGD_REF: CAL0000158306 homozygous diploid, classical genetics null BWP17 resistance to killing by host cells: decreased C. albicans orf19.3707 ORF YHB1 CAL0001071 PMID: 23856128|CGD_REF: CAL0000172540 homozygous diploid, classical genetics null BWP17 resistance to chemicals: decreased propolis C. albicans orf19.3707 ORF YHB1 CAL0001071 PMID: 15189992|CGD_REF: CAL0082041 homozygous diploid, classical genetics null Not recorded virulence: decreased mouse intravenous infection C. albicans orf19.3707 ORF YHB1 CAL0001071 PMID: 16030247|CGD_REF: CAL0114765 homozygous diploid, classical genetics null Not recorded virulence: decreased mouse intravenous infection C. albicans orf19.3707 ORF YHB1 CAL0001071 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.3708 ORF SAP2 CAL0001073 PMID: 9596782|CGD_REF: CAL0081875 heterozygous diploid, classical genetics null SC5314 hyphal growth: normal human umbilical vein endothelial cells reintegrant in vitro model of infection C. albicans orf19.3708 ORF SAP2 CAL0001073 PMID: 9596782|CGD_REF: CAL0081875 homozygous diploid, classical genetics null SC5314 hyphal growth: normal human umbilical vein endothelial cells in vitro model of infection C. albicans orf19.3708 ORF SAP2 CAL0001073 PMID: 9720053|CGD_REF: CAL0080688 heterozygous diploid, classical genetics overexpression Not recorded utilization of nitrogen source: increased BSA medium increased growth utilizing protein (BSA) as the nitrogen source C. albicans orf19.3708 ORF SAP2 CAL0001073 PMID: 12028383|CGD_REF: CAL0081896 heterozygous diploid, classical genetics null Not recorded utilization of nitrogen source: decreased BSA as nitrogen source phenotype is allele-specific: disruption of one SAP2 allele causes the phenotype whereas disruption of the other allele does not C. albicans orf19.3708 ORF SAP2 CAL0001073 PMID: 15820985|CGD_REF: CAL0082498 homozygous diploid, classical genetics null Not recorded utilization of nitrogen source: absent bovine serum albumin as sole nitrogen source; YCB/BSA medium C. albicans orf19.3708 ORF SAP2 CAL0001073 PMID: 18957582|CGD_REF: CAL0120457 homozygous diploid, classical genetics null Not recorded utilization of nitrogen source: absent bovine serum albumin as sole nitrogen source C. albicans orf19.3708 ORF SAP2 CAL0001073 PMID: 9284116|CGD_REF: CAL0081802 homozygous diploid, classical genetics null Not recorded vegetative growth: decreased rate YCB/BSA media also exhibits clumping C. albicans orf19.3708 ORF SAP2 CAL0001073 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.3708 ORF SAP2 CAL0001073 PMID: 12028383|CGD_REF: CAL0081896 heterozygous diploid, classical genetics null Not recorded viable C. albicans orf19.3708 ORF SAP2 CAL0001073 PMID: 12028383|CGD_REF: CAL0081896 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.3708 ORF SAP2 CAL0001073 PMID: 15820985|CGD_REF: CAL0082498 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.3708 ORF SAP2 CAL0001073 PMID: 9284116|CGD_REF: CAL0081802 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.3708 ORF SAP2 CAL0001073 PMID: 9720053|CGD_REF: CAL0080688 heterozygous diploid, classical genetics overexpression Not recorded viable C. albicans orf19.3708 ORF SAP2 CAL0001073 PMID: 9485603|CGD_REF: CAL0081808 homozygous diploid, classical genetics null Not recorded adhesion: decreased adhesion to human buccal epithelial cells C. albicans orf19.3708 ORF SAP2 CAL0001073 PMID: 9596782|CGD_REF: CAL0081875 heterozygous diploid, classical genetics null Not recorded adhesion: increased adhesion to human umbilical vein endothelial cells C. albicans orf19.3708 ORF SAP2 CAL0001073 PMID: 9596782|CGD_REF: CAL0081875 homozygous diploid, classical genetics null Not recorded adhesion: normal adhesion to human umbilical vein endothelial cells C. albicans orf19.3708 ORF SAP2 CAL0001073 PMID: 15845479|CGD_REF: CAL0082755 homozygous diploid, classical genetics null Other C. albicans induction of host response: decreased decreased cytokine induction ex vivo model of infection (reconstituted human vaginal epithelium) C. albicans orf19.3708 ORF SAP2 CAL0001073 PMID: 9596782|CGD_REF: CAL0081875 homozygous diploid, classical genetics null CAI-4 induction of host response: decreased decreased induction of host E-selectin expression ex vivo model of infection (human umbilical vein endothelial cells (HUVECs)) C. albicans orf19.3708 ORF SAP2 CAL0001073 PMID: 12761103|CGD_REF: CAL0081857 homozygous diploid, classical genetics null Not recorded virulence: decreased reconstituted human vaginal epithelium decreased capacity to invade and damage cells ex vivo model of infection C. albicans orf19.3708 ORF SAP2 CAL0001073 PMID: 10733678|CGD_REF: CAL0081828 homozygous diploid, classical genetics null SC5314 virulence: decreased reconstituted human epithelium decreased tissue damage (reconstituted human epidermis) ex vivo model of infection C. albicans orf19.3708 ORF SAP2 CAL0001073 PMID: 10540295|CGD_REF: CAL0081826 homozygous diploid, classical genetics null SC5314 virulence: decreased reconstituted human epithelium ex vivo model of infection C. albicans orf19.3708 ORF SAP2 CAL0001073 PMID: 9284116|CGD_REF: CAL0081802 homozygous diploid, classical genetics null Not recorded virulence: decreased guinea pig intravenous infection C. albicans orf19.3708 ORF SAP2 CAL0001073 PMID: 9596782|CGD_REF: CAL0081875 homozygous diploid, classical genetics null Not recorded virulence: decreased human umbilical vein endothelial cells decreased capacity to damage cells in vitro model of infection C. albicans orf19.3708 ORF SAP2 CAL0001073 PMID: 9596782|CGD_REF: CAL0081875 heterozygous diploid, classical genetics null Not recorded virulence: normal human umbilical vein endothelial cells normal damage to human cells in vitro model of infection C. albicans orf19.3708 ORF SAP2 CAL0001073 PMID: 9720053|CGD_REF: CAL0080688 heterozygous diploid, classical genetics overexpression Not recorded virulence: normal mouse gastrointestinal tract infection C. albicans orf19.3708 ORF SAP2 CAL0001073 PMID: 9284116|CGD_REF: CAL0081802 homozygous diploid, classical genetics null Not recorded virulence: decreased mouse intravenous infection C. albicans orf19.3708 ORF SAP2 CAL0001073 PMID: 9720053|CGD_REF: CAL0080688 heterozygous diploid, classical genetics overexpression Not recorded virulence: normal mouse intravenous infection C. albicans orf19.3708 ORF SAP2 CAL0001073 PMID: 10569785|CGD_REF: CAL0081876 homozygous diploid, classical genetics null CAI-4 virulence: normal mouse peritoneal infection C. albicans orf19.3708 ORF SAP2 CAL0001073 PMID: 9841840|CGD_REF: CAL0081814 homozygous diploid, classical genetics null Not recorded virulence: decreased rat vaginal infection C. albicans orf19.3708 ORF SAP2 CAL0001073 PMID: 9841840|CGD_REF: CAL0081814 heterozygous diploid, classical genetics null Not recorded virulence: normal rat vaginal infection C. albicans orf19.3710 ORF YHB5 CAL0001093 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.3710 ORF YHB5 CAL0001093 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: abnormal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.3710 ORF YHB5 CAL0001093 PMID: 15189992|CGD_REF: CAL0082041 homozygous diploid, classical genetics null Not recorded virulence: decreased slight decrease mouse intravenous infection C. albicans orf19.3710 ORF YHB5 CAL0001093 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.3710 ORF YHB5 CAL0001093 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.3711 ORF CAL0001094 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.3715 ORF ASF1 CAL0001104 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.3715 ORF ASF1 CAL0001104 PMID: 12524333|CGD_REF: CAL0080691 homozygous diploid, systematic mutation set (homozygous insertion mutants generated with URA3-ARG4-URA3 (UAU1) cassette) null BWP17 inviable homozygous null mutant strain could not be recovered, suggesting that the gene is essential under the selection conditions C. albicans orf19.3720 ORF CAL0001131 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.3720 ORF CAL0001131 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.3720 ORF CAL0001131 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.3720 ORF CAL0001131 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.3720 ORF CAL0001131 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient YPD medium C. albicans orf19.3720 ORF CAL0001131 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.3720 ORF CAL0001131 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 invasive growth: decreased solid SLAD media C. albicans orf19.3721 ORF CAL0001133 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient YPD medium C. albicans orf19.3722 ORF CAL0001135 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.3722 ORF CAL0001135 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.3722 ORF CAL0001135 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: decreased rate liquid synthetic complete medium C. albicans orf19.3722 ORF CAL0001135 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.3724 ORF CAL0001138 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.3727 ORF PHO112 CAL0001146 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.3734 ORF GEF2 CAL0001170 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.3736 ORF KAR4 CAL0001176 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.3736 ORF KAR4 CAL0001176 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.3736 ORF KAR4 CAL0001176 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.3736 ORF KAR4 CAL0001176 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.3736 ORF KAR4 CAL0001176 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.3740 ORF PGA23 CAL0001195 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.3740 ORF PGA23 CAL0001195 PMID: 18765290|CGD_REF: CAL0119430 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.3740 ORF PGA23 CAL0001195 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, competitive growth (haploinsufficient phenotype assay, barcode deletion set) null SC5314 resistance to chemicals: decreased amphotericin B C. albicans orf19.3740 ORF PGA23 CAL0001195 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, competitive growth (haploinsufficient phenotype assay, barcode deletion set) null SC5314 resistance to chemicals: decreased ergosterol analogs (ECC69 and/or ECC1384) C. albicans orf19.3743 ORF CAL0001198 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 invasive growth: decreased solid SLAD media C. albicans orf19.3744 ORF CAL0001199 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.3751 ORF CAL0001213 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.3752 ORF RAD51 CAL0001214 PMID: 19458191|CGD_REF: CAL0123591 homozygous diploid, classical genetics null Not recorded phenotypic switching: increased white-to-opaque switching C. albicans orf19.3752 ORF RAD51 CAL0001214 PMID: 20206282|CGD_REF: CAL0125104 homozygous diploid, classical genetics null rad51::hisG/rad51::hisG-URA3-hisG CAI-4 viable C. albicans orf19.3752 ORF RAD51 CAL0001214 PMID: 20206282|CGD_REF: CAL0125104 homozygous diploid, classical genetics null rad51::hisG/rad51::hisG-URA3-hisG CAI-4 vegetative growth: decreased rate C. albicans orf19.3752 ORF RAD51 CAL0001214 PMID: 20206282|CGD_REF: CAL0125104 homozygous diploid, classical genetics null rad51::hisG/rad51::hisG-URA3-hisG CAI-4 filamentous growth: increased C. albicans orf19.3752 ORF RAD51 CAL0001214 PMID: 20206282|CGD_REF: CAL0125104 heterozygous diploid, classical genetics null rad51::hisG-URA3-hisG CAI-4 UV resistance: decreased C. albicans orf19.3752 ORF RAD51 CAL0001214 PMID: 20206282|CGD_REF: CAL0125104 homozygous diploid, classical genetics null rad51::hisG/rad51::hisG-URA3-hisG CAI-4 UV resistance: decreased C. albicans orf19.3752 ORF RAD51 CAL0001214 PMID: 20206282|CGD_REF: CAL0125104 homozygous diploid, classical genetics null rad51::hisG/rad51::hisG-URA3-hisG CAI-4 resistance to chemicals: decreased methyl methanesulfonate C. albicans orf19.3752 ORF RAD51 CAL0001214 PMID: 20206282|CGD_REF: CAL0125104 homozygous diploid, classical genetics null rad51::hisG/rad51::hisG-URA3-hisG CAI-4 resistance to chemicals: decreased bleomycin C. albicans orf19.3752 ORF RAD51 CAL0001214 PMID: 20206282|CGD_REF: CAL0125104 homozygous diploid, classical genetics null rad51::hisG/rad51::hisG-URA3-hisG CAI-4 resistance to chemicals: decreased camptothecin C. albicans orf19.3752 ORF RAD51 CAL0001214 PMID: 20206282|CGD_REF: CAL0125104 homozygous diploid, classical genetics null rad51::hisG/rad51::hisG-URA3-hisG CAI-4 oxidative stress resistance: decreased hydrogen peroxide similar slight sensitivity seen with menadione or tBOOH C. albicans orf19.3753 ORF SEF1 CAL0001215 PMID: 20041210|CGD_REF: CAL0124764 homozygous diploid, systematic mutation set null SN152 resistance to chemicals: decreased BPS (500 uM bathophenanthrolinedisulfonic?acid, an iron chelator) severely sensitive C. albicans orf19.3753 ORF SEF1 CAL0001215 PMID: 17555439|CGD_REF: CAL0117968 homozygous diploid, classical genetics null Not recorded survival rate in stationary phase: decreased C. albicans orf19.3753 ORF SEF1 CAL0001215 PMID: 15964282|CGD_REF: CAL0114274 homozygous diploid, systematic mutation set (split-marker transposon insertion strategy to disrupt both alleles) null BWP17 viable C. albicans orf19.3753 ORF SEF1 CAL0001215 PMID: 20041210|CGD_REF: CAL0124764 homozygous diploid, systematic mutation set null SN152 alkaline pH resistance: decreased pH 10.5 strongly sensitive C. albicans orf19.3753 ORF SEF1 CAL0001215 PMID: 15964282|CGD_REF: CAL0114274 homozygous diploid, systematic mutation set (split-marker transposon insertion strategy to disrupt both alleles) null BWP17 biofilm formation: normal C. albicans orf19.3753 ORF SEF1 CAL0001215 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: decreased growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.3753 ORF SEF1 CAL0001215 PMID: 22073120|CGD_REF: CAL0000143592 homozygous diploid, classical genetics null BWP17 viable C. albicans orf19.3753 ORF SEF1 CAL0001215 PMID: 22073120|CGD_REF: CAL0000143592 homozygous diploid, classical genetics null BWP17 alkaline pH resistance: decreased C. albicans orf19.3753 ORF SEF1 CAL0001215 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.3753 ORF SEF1 CAL0001215 PMID: 22073120|CGD_REF: CAL0000143592 homozygous diploid, classical genetics null BWP17 hyphal growth: decreased C. albicans orf19.3753 ORF SEF1 CAL0001215 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.3753 ORF SEF1 CAL0001215 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient SLAD medium C. albicans orf19.3753 ORF SEF1 CAL0001215 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.3756 ORF CHR1 CAL0001218 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.3758 ORF CAL0001221 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.3758 ORF CAL0001221 PMID: 20494978|CGD_REF: CAL0125636 heterozygous diploid, classical genetics null BWP17 resistance to chemicals: decreased clotrimazole (75 uM) growth in liquid culture confirmation of mutant phenotypes for heterozygous transposon insertion strains showing sensitivity in a large-scale assay C. albicans orf19.3759 ORF CAL0001223 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.376 ORF CAL0004892 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.376 ORF CAL0004892 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: abnormal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.376 ORF CAL0004892 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.376 ORF CAL0004892 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.376 ORF CAL0004892 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.3760 ORF DLH1 CAL0001240 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.3761 ORF CDC54 CAL0001241 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.3763 ORF CAL0001243 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.3763 ORF CAL0001243 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.3763 ORF CAL0001243 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.3763 ORF CAL0001243 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.3763 ORF CAL0001243 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.3764 ORF GSG1 CAL0001244 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.3764 ORF GSG1 CAL0001244 PMID: 14663094|CGD_REF: CAL0080633 homozygous diploid, systematic mutation set (homozygous insertion mutants generated with URA3-ARG4-URA3 (UAU1) cassette) null BWP17 viable C. albicans orf19.3765 ORF RAX2 CAL0001245 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.3765 ORF RAX2 CAL0001245 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.3765 ORF RAX2 CAL0001245 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.3765 ORF RAX2 CAL0001245 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.3765 ORF RAX2 CAL0001245 PMID: 23608319|CGD_REF: CAL0000171942 homozygous diploid, classical genetics null rax2::HIS1/rax2::ARG4 BWP17 viable C. albicans orf19.3765 ORF RAX2 CAL0001245 PMID: 23608319|CGD_REF: CAL0000171942 homozygous diploid, classical genetics null rax2::HIS1/rax2::ARG4 BWP17 budding pattern: abnormal random bud site selection C. albicans orf19.3765 ORF RAX2 CAL0001245 PMID: 23608319|CGD_REF: CAL0000171942 homozygous diploid, classical genetics null rax2::HIS1/rax2::ARG4 BWP17 hyphal growth: abnormal curvier hyphae C. albicans orf19.3765 ORF RAX2 CAL0001245 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.377 ORF PHR3 CAL0004897 PMID: 17257864|CGD_REF: CAL0117713 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.377 ORF PHR3 CAL0004897 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 invasive growth: decreased solid SLAD media C. albicans orf19.3770 ORF ARG8 CAL0001267 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.3774 ORF PPG1 CAL0001271 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.3774 ORF PPG1 CAL0001271 PMID: 18708562|CGD_REF: CAL0119375 heterozygous diploid, classical genetics null Not recorded viable C. albicans orf19.3775 ORF SSK2 CAL0001272 PMID: 17804815|CGD_REF: CAL0118617 homozygous diploid, classical genetics null Not recorded resistance to chemicals: increased Calcofluor White C. albicans orf19.3775 ORF SSK2 CAL0001272 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.3775 ORF SSK2 CAL0001272 PMID: 17804815|CGD_REF: CAL0118617 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.3775 ORF SSK2 CAL0001272 PMID: 17804815|CGD_REF: CAL0118617 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased staurosporine C. albicans orf19.3775 ORF SSK2 CAL0001272 PMID: 17804815|CGD_REF: CAL0118617 homozygous diploid, classical genetics null Not recorded oxidative stress resistance: decreased hydrogen peroxide C. albicans orf19.3775 ORF SSK2 CAL0001272 PMID: 17804815|CGD_REF: CAL0118617 homozygous diploid, classical genetics null Not recorded metal resistance: decreased cadmium C. albicans orf19.3775 ORF SSK2 CAL0001272 PMID: 17804815|CGD_REF: CAL0118617 homozygous diploid, classical genetics null Not recorded osmotic stress resistance: decreased sodium chloride C. albicans orf19.3775 ORF SSK2 CAL0001272 PMID: 17804815|CGD_REF: CAL0118617 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased arsenic C. albicans orf19.3775 ORF SSK2 CAL0001272 PMID: 17804815|CGD_REF: CAL0118617 homozygous diploid, classical genetics null Not recorded oxidative stress resistance: decreased tert-butyl hydroperoxide C. albicans orf19.3775 ORF SSK2 CAL0001272 PMID: 17804815|CGD_REF: CAL0118617 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased caffeine C. albicans orf19.3775 ORF SSK2 CAL0001272 PMID: 17804815|CGD_REF: CAL0118617 homozygous diploid, classical genetics null Not recorded oxidative stress resistance: decreased menadione C. albicans orf19.3775 ORF SSK2 CAL0001272 PMID: 17804815|CGD_REF: CAL0118617 homozygous diploid, classical genetics null Not recorded osmotic stress resistance: decreased glucitol C. albicans orf19.3775 ORF SSK2 CAL0001272 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient YPD medium C. albicans orf19.3775 ORF SSK2 CAL0001272 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient SC medium C. albicans orf19.3775 ORF SSK2 CAL0001272 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient YNB medium C. albicans orf19.3775 ORF SSK2 CAL0001272 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient SLAD medium C. albicans orf19.3778 ORF CAL0001276 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, competitive growth (haploinsufficient phenotype assay, barcode deletion set) null SC5314 resistance to chemicals: decreased 5-fluorouracil C. albicans orf19.3778 ORF CAL0001276 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, competitive growth (haploinsufficient phenotype assay, barcode deletion set) null SC5314 resistance to chemicals: decreased flucytosine C. albicans orf19.3778 ORF CAL0001276 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.3780 ORF CAL0001294 PMID: 12524333|CGD_REF: CAL0080691 homozygous diploid, systematic mutation set (homozygous insertion mutants generated with URA3-ARG4-URA3 (UAU1) cassette) null BWP17 inviable homozygous null mutant strain could not be recovered, suggesting that the gene is essential under the selection conditions C. albicans orf19.3787 ORF CAL0001300 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.3791 ORF FGR10 CAL0001307 PMID: 12773383|CGD_REF: CAL0087974 heterozygous diploid, classical genetics (haploinsufficient phenotype assay) unspecified CAI-4 filamentous growth: decreased solid Spider medium transposon insertion proximal to, but not within, the ORF C. albicans orf19.3792 ORF CAL0001308 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.3794 ORF CSR1 CAL0001310 PMID: 20041210|CGD_REF: CAL0124764 homozygous diploid, systematic mutation set null SN152 resistance to chemicals: decreased BPS (150 uM bathophenanthrolinedisulfonic?acid, an iron chelator) severe sensitivity to this iron chelator may be due to chelation of zinc ions at high concentrations C. albicans orf19.3794 ORF CSR1 CAL0001310 PMID: 20041210|CGD_REF: CAL0124764 homozygous diploid, systematic mutation set null SN152 resistance to chemicals: decreased EDTA (0.75 mM ethylenediaminetetraacetic acid) severely sensitive C. albicans orf19.3794 ORF CSR1 CAL0001310 PMID: 18309267|CGD_REF: CAL0118912 homozygous diploid, classical genetics null Not recorded utilization of zinc source: decreased unable to grow under zinc-limiting conditions C. albicans orf19.3794 ORF CSR1 CAL0001310 PMID: 12773383|CGD_REF: CAL0087974 heterozygous diploid, classical genetics (haploinsufficient phenotype assay) null CAI-4 viable heterozygous deletion C. albicans orf19.3794 ORF CSR1 CAL0001310 PMID: 12773383|CGD_REF: CAL0087974 heterozygous diploid, classical genetics (haploinsufficient phenotype assay) null CAI-4 viable heterozygous transposon insertion C. albicans orf19.3794 ORF CSR1 CAL0001310 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.3794 ORF CSR1 CAL0001310 PMID: 18309267|CGD_REF: CAL0118912 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.3794 ORF CSR1 CAL0001310 PMID: 20041210|CGD_REF: CAL0124764 homozygous diploid, systematic mutation set null SN152 acid pH resistance: decreased pH 2.0 severely sensitive C. albicans orf19.3794 ORF CSR1 CAL0001310 PMID: 19529758|CGD_REF: CAL0123764 homozygous diploid, classical genetics null BWP17 biofilm formation: abnormal biofilm has glistening appearance due to increased accumulation of extracellular beta-1,3-glucan C. albicans orf19.3794 ORF CSR1 CAL0001310 PMID: 17880264|CGD_REF: CAL0118619 homozygous diploid, classical genetics null Not recorded inviable homozygous null mutant strain could not be recovered, suggesting that the gene is essential under the selection conditions C. albicans orf19.3794 ORF CSR1 CAL0001310 PMID: 20041210|CGD_REF: CAL0124764 homozygous diploid, systematic mutation set null SN152 colony appearance: abnormal Spider medium strongly decreased colony wrinkling C. albicans orf19.3794 ORF CSR1 CAL0001310 PMID: 20041210|CGD_REF: CAL0124764 homozygous diploid, systematic mutation set null SN152 colony color: abnormal CHROMagar medium at 30 and 37 deg C darker than normal C. albicans orf19.3794 ORF CSR1 CAL0001310 PMID: 12773383|CGD_REF: CAL0087974 heterozygous diploid, classical genetics (haploinsufficient phenotype assay) null CAI-4 filamentous growth: abnormal solid Spider medium decreased filamentation in the central part of the colony, with wild-type peripheral hyphae; heterozygous deletion C. albicans orf19.3794 ORF CSR1 CAL0001310 PMID: 12773383|CGD_REF: CAL0087974 heterozygous diploid, classical genetics (haploinsufficient phenotype assay) null CAI-4 filamentous growth: increased solid Spider medium heterozygous transposon insertion C. albicans orf19.3794 ORF CSR1 CAL0001310 PMID: 12773383|CGD_REF: CAL0087974 heterozygous diploid, classical genetics (haploinsufficient phenotype assay) unspecified CAI-4 filamentous growth: abnormal solid Spider medium increased or decreased filamentous growth, depending on the allele; heterozygous transposon insertion C. albicans orf19.3794 ORF CSR1 CAL0001310 PMID: 18309267|CGD_REF: CAL0118912 homozygous diploid, classical genetics null CAI-4 filamentous growth: abnormal C. albicans orf19.3794 ORF CSR1 CAL0001310 PMID: 19529758|CGD_REF: CAL0123764 homozygous diploid, classical genetics null Not recorded filamentous growth: decreased in biofilms C. albicans orf19.3794 ORF CSR1 CAL0001310 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: decreased growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.3794 ORF CSR1 CAL0001310 PMID: 21890817|CGD_REF: CAL0000142897 homozygous diploid, classical genetics null BWP17 biofilm formation: abnormal mutant biofilms produce excess beta-glucan and increased accumulation of yeast cells C. albicans orf19.3794 ORF CSR1 CAL0001310 PMID: 21890817|CGD_REF: CAL0000142897 homozygous diploid, classical genetics null BWP17 chemical compound accumulation: decreased farnesol C. albicans orf19.3794 ORF CSR1 CAL0001310 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: abnormal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.3794 ORF CSR1 CAL0001310 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.3794 ORF CSR1 CAL0001310 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.3795 ORF AGP3 CAL0001311 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.3796 ORF DCR1 CAL0001312 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.3796 ORF DCR1 CAL0001312 PMID: 22173636|CGD_REF: CAL0000143754 homozygous diploid, classical genetics null BWP17 inviable C. albicans orf19.3796 ORF DCR1 CAL0001312 PMID: 22173636|CGD_REF: CAL0000143754 heterozygous diploid, classical genetics repressible BWP17 vegetative growth: decreased rate C. albicans orf19.3798 ORF CAL0001314 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.3799 ORF CAL0001315 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.3799 ORF CAL0001315 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.3799 ORF CAL0001315 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.3799 ORF CAL0001315 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.3802 ORF PMT6 CAL0001900 PMID: 15659169|CGD_REF: CAL0082300 homozygous diploid, classical genetics null CAI-4 hyphal growth: absent Lee's or Spider media C. albicans orf19.3802 ORF PMT6 CAL0001900 PMID: 15659169|CGD_REF: CAL0082300 homozygous diploid, classical genetics null CAI-4 hyphal growth: normal oxygen-limited conditions C. albicans orf19.3802 ORF PMT6 CAL0001900 PMID: 15659169|CGD_REF: CAL0082300 homozygous diploid, classical genetics null CAI-4 hyphal growth: normal serum-containing medium C. albicans orf19.3802 ORF PMT6 CAL0001900 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.3802 ORF PMT6 CAL0001900 PMID: 10809683|CGD_REF: CAL0080975 homozygous diploid, classical genetics null pmt6::hisG/pmt6::hisG-URA3-hisG CAI-4 protein/peptide modification: normal Als1p is normally glycosylated Als1p C. albicans orf19.3802 ORF PMT6 CAL0001900 PMID: 10809683|CGD_REF: CAL0080975 homozygous diploid, classical genetics null pmt6::hisG/pmt6::hisG-URA3-hisG CAI-4 resistance to chemicals: normal amphotericin B C. albicans orf19.3802 ORF PMT6 CAL0001900 PMID: 10809683|CGD_REF: CAL0080975 homozygous diploid, classical genetics null pmt6::hisG/pmt6::hisG-URA3-hisG CAI-4 resistance to chemicals: normal clotrimazole C. albicans orf19.3802 ORF PMT6 CAL0001900 PMID: 10809683|CGD_REF: CAL0080975 homozygous diploid, classical genetics null pmt6::hisG/pmt6::hisG-URA3-hisG CAI-4 resistance to chemicals: normal fluconazole C. albicans orf19.3802 ORF PMT6 CAL0001900 PMID: 10809683|CGD_REF: CAL0080975 homozygous diploid, classical genetics null pmt6::hisG/pmt6::hisG-URA3-hisG CAI-4 resistance to chemicals: normal Calcofluor White C. albicans orf19.3802 ORF PMT6 CAL0001900 PMID: 10809683|CGD_REF: CAL0080975 homozygous diploid, classical genetics null pmt6::hisG/pmt6::hisG-URA3-hisG CAI-4 resistance to chemicals: normal sodium dodecyl sulfate C. albicans orf19.3802 ORF PMT6 CAL0001900 PMID: 10809683|CGD_REF: CAL0080975 homozygous diploid, classical genetics null pmt6::hisG/pmt6::hisG-URA3-hisG CAI-4 adhesion: decreased porcine aortic endothelial cells C. albicans orf19.3802 ORF PMT6 CAL0001900 PMID: 10809683|CGD_REF: CAL0080975 homozygous diploid, classical genetics null pmt6::hisG/pmt6::hisG-URA3-hisG CAI-4 hyphal growth: decreased solid Spider medium C. albicans orf19.3802 ORF PMT6 CAL0001900 PMID: 10809683|CGD_REF: CAL0080975 homozygous diploid, classical genetics null pmt6::hisG/pmt6::hisG-URA3-hisG CAI-4 hyphal growth: normal C. albicans orf19.3802 ORF PMT6 CAL0001900 PMID: 10809683|CGD_REF: CAL0080975 homozygous diploid, classical genetics null pmt6::hisG/pmt6::hisG-URA3-hisG CAI-4 resistance to chemicals: normal Congo red C. albicans orf19.3802 ORF PMT6 CAL0001900 PMID: 10809683|CGD_REF: CAL0080975 homozygous diploid, classical genetics null pmt6::hisG/pmt6::hisG-URA3-hisG CAI-4 resistance to chemicals: decreased Hygromycin B C. albicans orf19.3802 ORF PMT6 CAL0001900 PMID: 10809683|CGD_REF: CAL0080975 homozygous diploid, classical genetics null pmt6::hisG/pmt6::hisG-URA3-hisG CAI-4 resistance to chemicals: normal nystatin C. albicans orf19.3802 ORF PMT6 CAL0001900 PMID: 10809683|CGD_REF: CAL0080975 homozygous diploid, classical genetics null pmt6::hisG/pmt6::hisG-URA3-hisG CAI-4 resistance to chemicals: normal sodium orthovanadate C. albicans orf19.3802 ORF PMT6 CAL0001900 PMID: 10809683|CGD_REF: CAL0080975 homozygous diploid, classical genetics null pmt6::hisG/pmt6::hisG-URA3-hisG CAI-4 resistance to chemicals: normal fluphenazine C. albicans orf19.3802 ORF PMT6 CAL0001900 PMID: 10809683|CGD_REF: CAL0080975 homozygous diploid, classical genetics null pmt6::hisG/pmt6::hisG-URA3-hisG CAI-4 resistance to chemicals: normal G418 C. albicans orf19.3802 ORF PMT6 CAL0001900 PMID: 10809683|CGD_REF: CAL0080975 homozygous diploid, classical genetics null pmt6::hisG/pmt6::hisG-URA3-hisG CAI-4 viable C. albicans orf19.3802 ORF PMT6 CAL0001900 PMID: 10809683|CGD_REF: CAL0080975 homozygous diploid, classical genetics null pmt6::hisG/pmt6::hisG-URA3-hisG CAI-4 virulence: decreased mouse intravenous infection C. albicans orf19.3802 ORF PMT6 CAL0001900 PMID: 10809683|CGD_REF: CAL0080975 heterozygous diploid, classical genetics null pmt6::hisG-URA3-hisG/PMT6 CAI-4 hyphal growth: decreased solid Spider medium C. albicans orf19.3802 ORF PMT6 CAL0001900 PMID: 10809683|CGD_REF: CAL0080975 heterozygous diploid, classical genetics null pmt6::hisG-URA3-hisG/PMT6 CAI-4 hyphal growth: normal C. albicans orf19.3802 ORF PMT6 CAL0001900 PMID: 10809683|CGD_REF: CAL0080975 heterozygous diploid, classical genetics null pmt6::hisG-URA3-hisG/PMT6 CAI-4 resistance to chemicals: decreased Hygromycin B C. albicans orf19.3802 ORF PMT6 CAL0001900 PMID: 10809683|CGD_REF: CAL0080975 heterozygous diploid, classical genetics null pmt6::hisG-URA3-hisG/PMT6 CAI-4 viable SD medium wild-type growth rate C. albicans orf19.3802 ORF PMT6 CAL0001900 PMID: 17005840|CGD_REF: CAL0116746 homozygous diploid, classical genetics null CAF2-1 biofilm formation: decreased moderate reduction C. albicans orf19.3802 ORF PMT6 CAL0001900 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient YPD medium C. albicans orf19.3802 ORF PMT6 CAL0001900 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient SLAD medium C. albicans orf19.3803 ORF MNN22 CAL0001902 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.3803 ORF MNN22 CAL0001902 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.3803 ORF MNN22 CAL0001902 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.3803 ORF MNN22 CAL0001902 PMID: 23633946|CGD_REF: CAL0000172007 homozygous diploid, classical genetics null mnn22::dpl200/mnn22::dpl200 CAI-4 resistance to chemicals: decreased sodium dodecyl sulfate YPD agar plates containing 0.03% SDS C. albicans orf19.3803 ORF MNN22 CAL0001902 PMID: 23633946|CGD_REF: CAL0000172007 homozygous diploid, classical genetics null mnn22::dpl200/mnn22::dpl200 CAI-4 resistance to chemicals: decreased Calcofluor White YPD agar plates containing 100 ug/ml CFW C. albicans orf19.3803 ORF MNN22 CAL0001902 PMID: 23633946|CGD_REF: CAL0000172007 homozygous diploid, classical genetics null mnn22::dpl200/mnn22::dpl200 CAI-4 resistance to chemicals: decreased Congo Red YPD agar plates containing 100 ug/ml Congo Red C. albicans orf19.3803 ORF MNN22 CAL0001902 PMID: 23633946|CGD_REF: CAL0000172007 homozygous diploid, classical genetics null mnn22::dpl200/mnn22::dpl200 CAI-4 thermotolerance: decreased YPD agar plates, 42 degrees C C. albicans orf19.3803 ORF MNN22 CAL0001902 PMID: 23633946|CGD_REF: CAL0000172007 homozygous diploid, classical genetics null mnn22::dpl200/mnn22::dpl200 CAI-4 chemical compound accumulation: decreased mannan C. albicans orf19.3803 ORF MNN22 CAL0001902 PMID: 23633946|CGD_REF: CAL0000172007 homozygous diploid, classical genetics null mnn22::dpl200/mnn22::dpl200 CAI-4 induction of host response: decreased Deletion of MNN22 resulted in a 50% reduction in TNF-alpha secretion from PBMCs C. albicans orf19.3803 ORF MNN22 CAL0001902 PMID: 23633946|CGD_REF: CAL0000172007 homozygous diploid, classical genetics null mnn22::dpl200/mnn22::dpl200 CAI-4 virulence: decreased mutant allow increased survival time of larvae other model (G. mellonella larvae) C. albicans orf19.3803 ORF MNN22 CAL0001902 PMID: 23633946|CGD_REF: CAL0000172007 homozygous diploid, classical genetics null mnn22::dpl200/mnn22::dpl200 CAI-4 filamentous growth: delayed Spider medium, 30 degrees C C. albicans orf19.3803 ORF MNN22 CAL0001902 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.3804 ORF CAL0001904 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.3809 ORF BAS1 CAL0001915 PMID: 20041210|CGD_REF: CAL0124764 homozygous diploid, systematic mutation set null SN152 vegetative growth: decreased Lee's pH 4.5 medium at 30 deg C severely decreased C. albicans orf19.3809 ORF BAS1 CAL0001915 PMID: 15964282|CGD_REF: CAL0114274 homozygous diploid, systematic mutation set (split-marker transposon insertion strategy to disrupt both alleles) null BWP17 viable C. albicans orf19.3809 ORF BAS1 CAL0001915 PMID: 19463063|CGD_REF: CAL0123630 homozygous diploid, systematic mutation set (split-marker transposon insertion strategy to disrupt both alleles) null BWP17 viable C. albicans orf19.3809 ORF BAS1 CAL0001915 PMID: 15964282|CGD_REF: CAL0114274 homozygous diploid, systematic mutation set (split-marker transposon insertion strategy to disrupt both alleles) null BWP17 biofilm formation: normal C. albicans orf19.3809 ORF BAS1 CAL0001915 PMID: 20041210|CGD_REF: CAL0124764 homozygous diploid, systematic mutation set null SN152 auxotrophy adenine SD or MM media at 30 deg C C. albicans orf19.3809 ORF BAS1 CAL0001915 PMID: 20041210|CGD_REF: CAL0124764 homozygous diploid, systematic mutation set null SN152 colony appearance: abnormal Spider medium reduced colony wrinkling C. albicans orf19.3809 ORF BAS1 CAL0001915 PMID: 19463063|CGD_REF: CAL0123630 homozygous diploid, systematic mutation set (split-marker transposon insertion strategy to disrupt both alleles) null BWP17 virulence: normal Toll mutant D. melanogaster invasive infection insect infection C. albicans orf19.3810 ORF CAL0001938 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.3811 ORF GYP1 CAL0001941 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.3811 ORF GYP1 CAL0001941 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.3811 ORF GYP1 CAL0001941 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.3811 ORF GYP1 CAL0001941 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.3815 ORF CAL0001949 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.3817 ORF CAL0001954 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.3818 ORF GOA1 CAL0001957 PMID: 19717740|CGD_REF: CAL0124163 homozygous diploid, classical genetics null Not recorded respiratory growth: absent nonfermentable carbon sources glycerol, ethanol, or lactate C. albicans orf19.3818 ORF GOA1 CAL0001957 PMID: 19717740|CGD_REF: CAL0124163 homozygous diploid, classical genetics null BWP17 hyphal growth: absent SLAD or Spider media C. albicans orf19.3818 ORF GOA1 CAL0001957 PMID: 19717740|CGD_REF: CAL0124163 homozygous diploid, classical genetics null Not recorded vegetative growth: decreased rate C. albicans orf19.3818 ORF GOA1 CAL0001957 PMID: 14663094|CGD_REF: CAL0080633 homozygous diploid, systematic mutation set (homozygous insertion mutants generated with URA3-ARG4-URA3 (UAU1) cassette) null BWP17 viable C. albicans orf19.3818 ORF GOA1 CAL0001957 PMID: 19717740|CGD_REF: CAL0124163 homozygous diploid, classical genetics null Not recorded oxidative stress resistance: decreased hydrogen peroxide C. albicans orf19.3818 ORF GOA1 CAL0001957 PMID: 19717740|CGD_REF: CAL0124163 homozygous diploid, classical genetics null Not recorded chlamydospore formation: absent C. albicans orf19.3818 ORF GOA1 CAL0001957 PMID: 12524333|CGD_REF: CAL0080691 homozygous diploid, systematic mutation set (homozygous insertion mutants generated with URA3-ARG4-URA3 (UAU1) cassette) null BWP17 inviable homozygous null mutant strain could not be recovered, suggesting that the gene is essential under the selection conditions C. albicans orf19.3818 ORF GOA1 CAL0001957 PMID: 19717740|CGD_REF: CAL0124163 homozygous diploid, classical genetics null Not recorded oxidative stress resistance: decreased menadione C. albicans orf19.3818 ORF GOA1 CAL0001957 PMID: 19717740|CGD_REF: CAL0124163 homozygous diploid, classical genetics null BWP17 resistance to killing by host cells: decreased increased sensitivity to killing by polymorphonuclear neutrophils in vitro model of infection (polymorphonuclear neutrophil culture) C. albicans orf19.3818 ORF GOA1 CAL0001957 PMID: 21398508|CGD_REF: CAL0141806 homozygous diploid, classical genetics null SC5314 oxidative phosphorylation: decreased C. albicans orf19.3818 ORF GOA1 CAL0001957 PMID: 21398508|CGD_REF: CAL0141806 homozygous diploid, classical genetics null SC5314 resistance to chemicals: decreased rotenone C. albicans orf19.3818 ORF GOA1 CAL0001957 PMID: 21398508|CGD_REF: CAL0141806 homozygous diploid, classical genetics null SC5314 chronological lifespan: decreased C. albicans orf19.3818 ORF GOA1 CAL0001957 PMID: 21398508|CGD_REF: CAL0141806 homozygous diploid, classical genetics null SC5314 apoptosis: increased C. albicans orf19.3818 ORF GOA1 CAL0001957 PMID: 19717740|CGD_REF: CAL0124163 homozygous diploid, classical genetics null Not recorded virulence: decreased mouse intravenous infection C. albicans orf19.3818 ORF GOA1 CAL0001957 PMID: 23490206|CGD_REF: CAL0000158698 homozygous diploid, classical genetics null SC5314 viable: increased in vitro model of infection (RAW264.7) C. albicans orf19.3818 ORF GOA1 CAL0001957 PMID: 23490206|CGD_REF: CAL0000158698 homozygous diploid, classical genetics null SC5314 flocculation: increased RPMI after 6 h C. albicans orf19.3818 ORF GOA1 CAL0001957 PMID: 23490206|CGD_REF: CAL0000158698 homozygous diploid, classical genetics null SC5314 resistance to chemicals: decreased Calcofluor White|Congo Red C. albicans orf19.3818 ORF GOA1 CAL0001957 PMID: 23490206|CGD_REF: CAL0000158698 homozygous diploid, classical genetics null SC5314 resistance to killing by host cells: normal in vitro model of infection (RAW264.7) C. albicans orf19.3818 ORF GOA1 CAL0001957 PMID: 23490206|CGD_REF: CAL0000158698 homozygous diploid, classical genetics null SC5314 induction of host response: decreased decreased recognition and endocytosis of goa1 by FaDu epithelial cell line in vitro model of infection (RAW264.7) C. albicans orf19.3818 ORF GOA1 CAL0001957 PMID: 23490206|CGD_REF: CAL0000158698 homozygous diploid, classical genetics null SC5314 resistance to phagocytosis: increased goa1 mutant is phagocytosed poorly by mouse phagocytes in vitro model of infection (RAW264.7) C. albicans orf19.382 ORF TEF2 CAL0004916 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient YPD medium C. albicans orf19.382 ORF TEF2 CAL0004916 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient YNB medium C. albicans orf19.3820 ORF CAL0001980 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient SLAD medium C. albicans orf19.3822 ORF SCS7 CAL0001985 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.3823 ORF ZDS1 CAL0001987 PMID: 11737862|CGD_REF: CAL0080988 heterozygous diploid, classical genetics null Not recorded viable C. albicans orf19.3823 ORF ZDS1 CAL0001987 PMID: 11737862|CGD_REF: CAL0080988 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.3825 ORF RCE1 CAL0001992 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.3825 ORF RCE1 CAL0001992 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.3825 ORF RCE1 CAL0001992 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.3825 ORF RCE1 CAL0001992 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.3828 ORF CAL0002000 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.3829 ORF PHR1 CAL0002002 PMID: 18765290|CGD_REF: CAL0119430 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased Calcofluor White C. albicans orf19.3829 ORF PHR1 CAL0002002 PMID: 9422607|CGD_REF: CAL0081334 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased Calcofluor White C. albicans orf19.3829 ORF PHR1 CAL0002002 PMID: 7591097|CGD_REF: CAL0081714 homozygous diploid, classical genetics null Other C. albicans hyphal growth: absent in mouse kidney C. albicans orf19.3829 ORF PHR1 CAL0002002 PMID: 9315654|CGD_REF: CAL0081715 homozygous diploid, classical genetics null Not recorded vegetative growth: decreased rate alkaline pH C. albicans orf19.3829 ORF PHR1 CAL0002002 PMID: 10559174|CGD_REF: CAL0081719 homozygous diploid, classical genetics null Other C. albicans viable C. albicans orf19.3829 ORF PHR1 CAL0002002 PMID: 7823929|CGD_REF: CAL0081331 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.3829 ORF PHR1 CAL0002002 PMID: 10974097|CGD_REF: CAL0081722 heterozygous diploid, classical genetics null phr1::hisG/PHR1 Other C. albicans viable C. albicans orf19.3829 ORF PHR1 CAL0002002 PMID: 10974097|CGD_REF: CAL0081722 homozygous diploid, classical genetics null phr1::hisG/phr1::hisG-URA3-hisG Other C. albicans filamentous growth: absent M199, pH 8, 37 deg C mutants lack filaments and cells are highly vacuolated C. albicans orf19.3829 ORF PHR1 CAL0002002 PMID: 10974097|CGD_REF: CAL0081722 homozygous diploid, classical genetics null phr1::hisG/phr1::hisG-URA3-hisG Other C. albicans viable C. albicans orf19.3829 ORF PHR1 CAL0002002 PMID: 18765290|CGD_REF: CAL0119430 homozygous diploid, classical genetics null Not recorded cell wall morphology: abnormal increased thickness of central chitin/glucan layer C. albicans orf19.3829 ORF PHR1 CAL0002002 PMID: 7823929|CGD_REF: CAL0081331 homozygous diploid, classical genetics null Not recorded cellular morphology: abnormal abnormal morphology of both yeast-form cells and germ tubes at alkaline pH C. albicans orf19.3829 ORF PHR1 CAL0002002 PMID: 18765290|CGD_REF: CAL0119430 homozygous diploid, classical genetics null Not recorded chitin deposition: increased C. albicans orf19.3829 ORF PHR1 CAL0002002 PMID: 9422607|CGD_REF: CAL0081334 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased nikkomycin Z C. albicans orf19.3829 ORF PHR1 CAL0002002 PMID: 18765290|CGD_REF: CAL0119430 homozygous diploid, classical genetics null Not recorded resistance to chemicals: increased caspofungin C. albicans orf19.3829 ORF PHR1 CAL0002002 PMID: 18765290|CGD_REF: CAL0119430 homozygous diploid, classical genetics null Not recorded chemical compound accumulation: increased glucan increased cell wall glucan C. albicans orf19.3829 ORF PHR1 CAL0002002 PMID: 20430812|CGD_REF: CAL0125756 homozygous diploid, classical genetics null Other C. albicans interaction with host/environment: decreased mutant unable to penetrate a reconstructed human epithelium ex vivo model of infection (reconstructed human epithelium) C. albicans orf19.3829 ORF PHR1 CAL0002002 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: decreased growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.3829 ORF PHR1 CAL0002002 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: abnormal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.3829 ORF PHR1 CAL0002002 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, classical genetics null SN152 germ tube formation: decreased serum-containing medium C. albicans orf19.3829 ORF PHR1 CAL0002002 PMID: 22876186|CGD_REF: CAL0000157675 homozygous diploid, classical genetics null BWP17 resistance to chemicals: decreased fluconazole C. albicans orf19.3829 ORF PHR1 CAL0002002 PMID: 22876186|CGD_REF: CAL0000157675 homozygous diploid, classical genetics null BWP17 biofilm formation: decreased C. albicans orf19.3829 ORF PHR1 CAL0002002 PMID: 9632601|CGD_REF: CAL0081716 heterozygous diploid, classical genetics null Not recorded virulence: decreased virulence is intermediate between that of the homozygous null mutant and wild type mouse intravenous infection C. albicans orf19.3829 ORF PHR1 CAL0002002 PMID: 7591097|CGD_REF: CAL0081714 homozygous diploid, classical genetics null Not recorded virulence: absent mouse intravenous infection C. albicans orf19.3829 ORF PHR1 CAL0002002 PMID: 9632601|CGD_REF: CAL0081716 homozygous diploid, classical genetics null Not recorded virulence: decreased mouse intravenous infection C. albicans orf19.3829 ORF PHR1 CAL0002002 PMID: 9632601|CGD_REF: CAL0081716 heterozygous diploid, classical genetics null Not recorded virulence: normal rat vaginal infection C. albicans orf19.3829 ORF PHR1 CAL0002002 PMID: 9632601|CGD_REF: CAL0081716 homozygous diploid, classical genetics null Not recorded virulence: normal rat vaginal infection C. albicans orf19.3829 ORF PHR1 CAL0002002 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.3829 ORF PHR1 CAL0002002 PMID: 20375342|CGD_REF: CAL0125177 homozygous diploid, classical genetics null SC5314 invasive growth: decreased porcine corneal tissue depth of hyphal penetration into corneal tissue is reduced ex vivo model of infection C. albicans orf19.3829 ORF PHR1 CAL0002002 PMID: 20375342|CGD_REF: CAL0125177 homozygous diploid, classical genetics null SC5314 filamentous growth: absent solid M199 medium pH 7.3 or 8.0 C. albicans orf19.3829 ORF PHR1 CAL0002002 PMID: 20375342|CGD_REF: CAL0125177 homozygous diploid, classical genetics null SC5314 virulence: absent BALB/C or C57BL/6J mice mouse corneal infection C. albicans orf19.3829 ORF PHR1 CAL0002002 PMID: 20430812|CGD_REF: CAL0125756 homozygous diploid, classical genetics null Other C. albicans adhesion: decreased mutant defective in adhesion to abiotic surfaces ex vivo model of infection C. albicans orf19.3829 ORF PHR1 CAL0002002 PMID: 20430812|CGD_REF: CAL0125756 homozygous diploid, classical genetics null Other C. albicans adhesion: decreased mutant defective in adhesion to monolayers of epithelial cells ex vivo model of infection C. albicans orf19.3829 ORF PHR1 CAL0002002 PMID: 20430812|CGD_REF: CAL0125756 homozygous diploid, classical genetics null Other C. albicans hyphal growth: abnormal hyphal-growth inducing conditions defective hyphal elongation ex vivo model of infection C. albicans orf19.3829 ORF PHR1 CAL0002002 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.3831 ORF CAL0002023 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.3833 ORF CAL0002026 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.3833 ORF CAL0002026 PMID: 15964282|CGD_REF: CAL0114274 homozygous diploid, systematic mutation set (split-marker transposon insertion strategy to disrupt both alleles) null BWP17 viable C. albicans orf19.3833 ORF CAL0002026 PMID: 15964282|CGD_REF: CAL0114274 homozygous diploid, systematic mutation set (split-marker transposon insertion strategy to disrupt both alleles) null BWP17 biofilm formation: normal C. albicans orf19.3838 ORF EFB1 CAL0002038 PMID: 14507372|CGD_REF: CAL0088818 heterozygous diploid, large-scale survey (large-scale identification of essential genes by gene replacement and conditional expression (GRACE) method) repressible CAI-4 viable one allele is deleted and the other is placed under repressible Tet promoter C. albicans orf19.3839 ORF SAP10 CAL0002041 PMID: 16269404|CGD_REF: CAL0115363 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased Calcofluor White C. albicans orf19.3839 ORF SAP10 CAL0002041 PMID: 16269404|CGD_REF: CAL0115363 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased itraconazole C. albicans orf19.3839 ORF SAP10 CAL0002041 PMID: 15820985|CGD_REF: CAL0082498 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.3839 ORF SAP10 CAL0002041 PMID: 16269404|CGD_REF: CAL0115363 heterozygous diploid, classical genetics null Not recorded viable C. albicans orf19.3839 ORF SAP10 CAL0002041 PMID: 16269404|CGD_REF: CAL0115363 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.3839 ORF SAP10 CAL0002041 PMID: 16269404|CGD_REF: CAL0115363 homozygous diploid, classical genetics null Not recorded adhesion: decreased adhesion to human buccal epithelial cells C. albicans orf19.3839 ORF SAP10 CAL0002041 PMID: 16269404|CGD_REF: CAL0115363 homozygous diploid, classical genetics null Not recorded chitin deposition: increased increased cell wall chitin C. albicans orf19.3839 ORF SAP10 CAL0002041 PMID: 16269404|CGD_REF: CAL0115363 homozygous diploid, classical genetics null Not recorded cytokinesis: absent C. albicans orf19.3839 ORF SAP10 CAL0002041 PMID: 16269404|CGD_REF: CAL0115363 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased Congo Red C. albicans orf19.3839 ORF SAP10 CAL0002041 PMID: 16269404|CGD_REF: CAL0115363 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased Hygromycin B C. albicans orf19.3839 ORF SAP10 CAL0002041 PMID: 16269404|CGD_REF: CAL0115363 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased amorolfine C. albicans orf19.3839 ORF SAP10 CAL0002041 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.3839 ORF SAP10 CAL0002041 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.3839 ORF SAP10 CAL0002041 PMID: 21097664|CGD_REF: CAL0139899 homozygous diploid, classical genetics null CAI-4 resistance to phagocytosis: normal in vitro model of infection (human macrophages) C. albicans orf19.3839 ORF SAP10 CAL0002041 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.3839 ORF SAP10 CAL0002041 PMID: 16269404|CGD_REF: CAL0115363 homozygous diploid, classical genetics null Not recorded virulence: decreased reconstituted human epithelium ex vivo model of infection C. albicans orf19.3839 ORF SAP10 CAL0002041 PMID: 16269404|CGD_REF: CAL0115363 homozygous diploid, classical genetics null Not recorded virulence: decreased mouse intravenous infection C. albicans orf19.3839 ORF SAP10 CAL0002041 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.3840 ORF CAL0002060 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.3841 ORF CAL0002062 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.3843 ORF CAL0002063 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.3843 ORF CAL0002063 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 invasive growth: decreased solid SLAD media C. albicans orf19.3844 ORF MRP8 CAL0002064 PMID: 14663094|CGD_REF: CAL0080633 homozygous diploid, systematic mutation set (homozygous insertion mutants generated with URA3-ARG4-URA3 (UAU1) cassette) null BWP17 viable C. albicans orf19.3844 ORF MRP8 CAL0002064 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 invasive growth: decreased solid SLAD media C. albicans orf19.3845 ORF FGR3 CAL0002065 PMID: 12773383|CGD_REF: CAL0087974 heterozygous diploid, classical genetics (haploinsufficient phenotype assay) null CAI-4 viable heterozygous deletion or transposon insertion C. albicans orf19.3845 ORF FGR3 CAL0002065 PMID: 12773383|CGD_REF: CAL0087974 heterozygous diploid, classical genetics (haploinsufficient phenotype assay) null CAI-4 filamentous growth: decreased solid Spider medium heterozygous deletion or transposon insertion C. albicans orf19.3845 ORF FGR3 CAL0002065 PMID: 12773383|CGD_REF: CAL0087974 heterozygous diploid, classical genetics (haploinsufficient phenotype assay) null CAI-4 filamentous growth: increased solid YEPD plus serum heterozygous deletion or transposon insertion C. albicans orf19.3845 ORF FGR3 CAL0002065 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.3845 ORF FGR3 CAL0002065 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: abnormal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.3845 ORF FGR3 CAL0002065 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.3845 ORF FGR3 CAL0002065 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.3845 ORF FGR3 CAL0002065 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 invasive growth: decreased solid SLAD media C. albicans orf19.3846 ORF LYS4 CAL0002066 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.385 ORF GCV2 CAL0004920 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.3852 ORF CAL0002088 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.3854 ORF CAL0002089 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.3854 ORF CAL0002089 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.3854 ORF CAL0002089 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: abnormal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.3854 ORF CAL0002089 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.3854 ORF CAL0002089 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.3856 ORF CDC28 CAL0002090 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.3856 ORF CDC28 CAL0002090 PMID: 16710830|CGD_REF: CAL0116044 heterozygous diploid, classical genetics repressible CAI-4 hyphal growth: abnormal abnormal hyphal morphology C. albicans orf19.3856 ORF CDC28 CAL0002090 PMID: 17765684|CGD_REF: CAL0118343 heterozygous diploid, classical genetics repressible BWP17 hyphal growth: abnormal cdc28as mutation causes sensitivity to 1NM-PP1 (ATP analog); inhibition causes wide surface structures but no true hyphae to be formed under hyphal-inducing conditions (and defect in Cdc11p phosphorylation) C. albicans orf19.3856 ORF CDC28 CAL0002090 PMID: 15659158|CGD_REF: CAL0082298 heterozygous diploid, classical genetics reduction of function cdc28-Y18F (mutation in predicted phosphorylation site) Not recorded viable C. albicans orf19.3856 ORF CDC28 CAL0002090 PMID: 16710830|CGD_REF: CAL0116044 heterozygous diploid, classical genetics repressible Not recorded cell shape: abnormal highly elongated cells C. albicans orf19.3856 ORF CDC28 CAL0002090 PMID: 14507372|CGD_REF: CAL0088818 heterozygous diploid, large-scale survey (large-scale identification of essential genes by gene replacement and conditional expression (GRACE) method) repressible CAI-4 inviable one allele is deleted and the other is placed under repressible Tet promoter C. albicans orf19.3859 ORF CAL0002094 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.386 ORF SAM4 CAL0004923 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 invasive growth: decreased solid SLAD media C. albicans orf19.3861 ORF SIS1 CAL0002119 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.3861 ORF SIS1 CAL0002119 PMID: 19115836|CGD_REF: CAL0122036 heterozygous diploid, competitive growth (haploinsufficient phenotype assay, barcode deletion set) null SC5314 resistance to chemicals: decreased virgineone C. albicans orf19.3862 ORF CAL0002120 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.3862 ORF CAL0002120 PMID: 19115836|CGD_REF: CAL0122036 heterozygous diploid, competitive growth (haploinsufficient phenotype assay, barcode deletion set) null SC5314 resistance to chemicals: decreased rapamycin C. albicans orf19.3863 ORF CAL0002121 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.3863 ORF CAL0002121 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.3863 ORF CAL0002121 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.3863 ORF CAL0002121 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.3865 ORF RFX1 CAL0002122 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.3867 ORF RPL7 CAL0002123 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.3869 ORF CAL0002127 PMID: 17873081|CGD_REF: CAL0118685 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.3869 ORF CAL0002127 PMID: 17873081|CGD_REF: CAL0118685 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased caspofungin C. albicans orf19.387 ORF GCR3 CAL0004925 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.3870 ORF ADE13 CAL0002147 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.3872 ORF CAL0002150 PMID: 22438810|CGD_REF: CAL0000156986 homozygous diploid, classical genetics null BWP17 viable C. albicans orf19.3872 ORF CAL0002150 PMID: 22438810|CGD_REF: CAL0000156986 homozygous diploid, classical genetics null BWP17 virulence: decreased mutants have reduced capacity to damage oral epithelial cells in vitro model of infection (monolayers of oral epithelial cells) C. albicans orf19.3873 ORF ARC40 CAL0002151 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.3873 ORF ARC40 CAL0002151 PMID: 12773383|CGD_REF: CAL0087974 heterozygous diploid, classical genetics (haploinsufficient phenotype assay) unspecified CAI-4 filamentous growth: increased solid Spider medium transposon insertion proximal to, but not within, the ORF C. albicans orf19.3874 ORF CAL0002152 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.3874 ORF CAL0002152 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.3874 ORF CAL0002152 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.3874 ORF CAL0002152 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.3874 ORF CAL0002152 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.3878 ORF CAL0002156 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.3878 ORF CAL0002156 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.3878 ORF CAL0002156 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.3878 ORF CAL0002156 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.388 ORF CAF16 CAL0004927 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.3884 ORF FGR50 CAL0002180 PMID: 12773383|CGD_REF: CAL0087974 heterozygous diploid, classical genetics (haploinsufficient phenotype assay) unspecified CAI-4 filamentous growth: increased solid Spider medium transposon insertion proximal to, but not within, the ORF C. albicans orf19.3884 ORF FGR50 CAL0002180 PMID: 20494978|CGD_REF: CAL0125636 heterozygous diploid, classical genetics null BWP17 resistance to chemicals: decreased clotrimazole (75 uM) growth in liquid culture confirmation of mutant phenotypes for heterozygous transposon insertion strains showing sensitivity in a large-scale assay C. albicans orf19.3885 ORF CAL0002181 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.3885 ORF CAL0002181 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.3885 ORF CAL0002181 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.3885 ORF CAL0002181 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.3888 ORF PGI1 CAL0002184 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.3888.2 ORF CAF0006999 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 invasive growth: decreased solid SLAD media C. albicans orf19.3893 ORF SCW11 CAL0002202 PMID: 17873081|CGD_REF: CAL0118685 homozygous diploid, classical genetics null Not recorded inviable homozygous null mutant strain could not be recovered, suggesting that the gene is essential under the selection conditions C. albicans orf19.3894 ORF CAL0002203 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.3894 ORF CAL0002203 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, competitive growth (haploinsufficient phenotype assay, barcode deletion set) null SC5314 resistance to chemicals: decreased ergosterol analogs (ECC69 and/or ECC1384) C. albicans orf19.3894 ORF CAL0002203 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.3894 ORF CAL0002203 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.3894 ORF CAL0002203 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.3894 ORF CAL0002203 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.3895 ORF CHT2 CAL0002204 PMID: 16214381|CGD_REF: CAL0114979 homozygous diploid, classical genetics null BWP17 germ tube formation: normal serum-containing medium C. albicans orf19.3895 ORF CHT2 CAL0002204 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.3895 ORF CHT2 CAL0002204 PMID: 14507372|CGD_REF: CAL0088818 heterozygous diploid, large-scale survey (large-scale identification of essential genes by gene replacement and conditional expression (GRACE) method) repressible CAI-4 viable one allele is deleted and the other is placed under repressible Tet promoter C. albicans orf19.3895 ORF CHT2 CAL0002204 PMID: 16214381|CGD_REF: CAL0114979 heterozygous diploid, classical genetics null Not recorded viable C. albicans orf19.3895 ORF CHT2 CAL0002204 PMID: 16214381|CGD_REF: CAL0114979 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.3895 ORF CHT2 CAL0002204 PMID: 18765290|CGD_REF: CAL0119430 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.3895 ORF CHT2 CAL0002204 PMID: 19779551|CGD_REF: CAL0124331 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.3895 ORF CHT2 CAL0002204 PMID: 19779551|CGD_REF: CAL0124331 homozygous diploid, classical genetics null CAF2-1 hyphal growth: abnormal serum-containing medium at 37 deg C C. albicans orf19.3895 ORF CHT2 CAL0002204 PMID: 19779551|CGD_REF: CAL0124331 homozygous diploid, classical genetics null Not recorded colony appearance: abnormal solid Spider medium C. albicans orf19.3895 ORF CHT2 CAL0002204 PMID: 16214381|CGD_REF: CAL0114979 homozygous diploid, classical genetics null BWP17 filamentous growth: increased increased filamentation at colony periphery C. albicans orf19.3895 ORF CHT2 CAL0002204 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: decreased growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.3895 ORF CHT2 CAL0002204 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.3895 ORF CHT2 CAL0002204 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.3895 ORF CHT2 CAL0002204 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.3898 ORF CAL0002206 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.390 ORF CDC42 CAL0004942 PMID: 15189993|CGD_REF: CAL0080878 heterozygous diploid, classical genetics reduction of function SC5314 germ tube formation: decreased various media C. albicans orf19.390 ORF CDC42 CAL0004942 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.390 ORF CDC42 CAL0004942 PMID: 12455975|CGD_REF: CAL0080875 heterozygous diploid, classical genetics overexpression CAI-4 viable no apparent phenotype C. albicans orf19.390 ORF CDC42 CAL0004942 PMID: 15755921|CGD_REF: CAL0082335 heterozygous diploid, classical genetics overexpression Not recorded viable C. albicans orf19.390 ORF CDC42 CAL0004942 PMID: 15755921|CGD_REF: CAL0082335 heterozygous diploid, classical genetics repressible BWP17 hyphal growth: abnormal solid serum-containing medium elongated buds, indicating that hyphal growth is induced but not maintained C. albicans orf19.390 ORF CDC42 CAL0004942 PMID: 12455975|CGD_REF: CAL0080875 heterozygous diploid, classical genetics activation CAI-4 hyphal growth: abnormal multibranched hyphae C. albicans orf19.390 ORF CDC42 CAL0004942 PMID: 12582118|CGD_REF: CAL0080793 heterozygous diploid, classical genetics misexpression BWP17 hyphal growth: decreased liquid media plus serum severe decrease C. albicans orf19.390 ORF CDC42 CAL0004942 PMID: 12366849|CGD_REF: CAL0080792 heterozygous diploid, classical genetics repressible CAI-4 hyphal growth: decreased RPMI 1640 medium plus serum some hyphal markers are still expressed C. albicans orf19.390 ORF CDC42 CAL0004942 PMID: 12582118|CGD_REF: CAL0080793 heterozygous diploid, classical genetics misexpression BWP17 hyphal growth: absent solid media, with or without serum C. albicans orf19.390 ORF CDC42 CAL0004942 PMID: 16087738|CGD_REF: CAL0114510 heterozygous diploid, classical genetics dominant negative CDC42-D118A Not recorded inviable terminal phenotype is enlarged, multinucleate cells C. albicans orf19.390 ORF CDC42 CAL0004942 PMID: 17093060|CGD_REF: CAL0117112 heterozygous diploid, classical genetics activation CDC42-G12V (constitutively GTP bound) BWP17 cellular morphology: abnormal loss of polarity and abnormal septin bar formation C. albicans orf19.390 ORF CDC42 CAL0004942 PMID: 12455975|CGD_REF: CAL0080875 heterozygous diploid, classical genetics repressible CAI-4 budding: absent C. albicans orf19.390 ORF CDC42 CAL0004942 PMID: 15755921|CGD_REF: CAL0082335 heterozygous diploid, classical genetics overexpression BWP17 invasive growth: normal C. albicans orf19.390 ORF CDC42 CAL0004942 PMID: 16467473|CGD_REF: CAL0115508 heterozygous diploid, classical genetics repressible Not recorded cell size: increased C. albicans orf19.390 ORF CDC42 CAL0004942 PMID: 12366849|CGD_REF: CAL0080792 homozygous diploid, classical genetics null Not recorded inviable cells fail to bud or separate after excision of CDC42 is induced C. albicans orf19.390 ORF CDC42 CAL0004942 PMID: 12455975|CGD_REF: CAL0080875 heterozygous diploid, classical genetics activation CAI-4 inviable multibudded cells C. albicans orf19.390 ORF CDC42 CAL0004942 PMID: 12455975|CGD_REF: CAL0080875 heterozygous diploid, classical genetics dominant negative CAI-4 inviable multinucleate cells C. albicans orf19.390 ORF CDC42 CAL0004942 PMID: 16087738|CGD_REF: CAL0114510 homozygous diploid, classical genetics null Not recorded inviable terminal phenotype is enlarged, multinucleate cells C. albicans orf19.390 ORF CDC42 CAL0004942 PMID: 12455975|CGD_REF: CAL0080875 heterozygous diploid, classical genetics repressible CAI-4 inviable C. albicans orf19.390 ORF CDC42 CAL0004942 PMID: 12582118|CGD_REF: CAL0080793 heterozygous diploid, classical genetics repressible BWP17 inviable C. albicans orf19.390 ORF CDC42 CAL0004942 PMID: 16467473|CGD_REF: CAL0115508 heterozygous diploid, classical genetics repressible BWP17 filamentous growth: abnormal subtle defect in agar-embedded growth; shorter filaments than wild-type C. albicans orf19.390 ORF CDC42 CAL0004942 PMID: 12582118|CGD_REF: CAL0080793 heterozygous diploid, classical genetics misexpression BWP17 virulence: absent mouse intravenous infection C. albicans orf19.3901 ORF CAL0002814 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.3901 ORF CAL0002814 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.3901 ORF CAL0002814 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.3901 ORF CAL0002814 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.3901 ORF CAL0002814 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.3902 ORF MRV2 CAL0002816 PMID: 24281718|CGD_REF: CAL0000173710 homozygous diploid, classical genetics null BWP17 viable C. albicans orf19.3903 ORF MRV3 CAL0002817 PMID: 24281718|CGD_REF: CAL0000173710 homozygous diploid, classical genetics null BWP17 viable C. albicans orf19.3904 ORF MRV4 CAL0002820 PMID: 24281718|CGD_REF: CAL0000173710 homozygous diploid, classical genetics null BWP17 viable C. albicans orf19.3905 ORF MRV5 CAL0002822 PMID: 24281718|CGD_REF: CAL0000173710 homozygous diploid, classical genetics null BWP17 viable C. albicans orf19.3906 ORF MRV6 CAL0002824 PMID: 14663094|CGD_REF: CAL0080633 homozygous diploid, systematic mutation set (homozygous insertion mutants generated with URA3-ARG4-URA3 (UAU1) cassette) null BWP17 viable C. albicans orf19.3906 ORF MRV6 CAL0002824 PMID: 24281718|CGD_REF: CAL0000173710 homozygous diploid, classical genetics null BWP17 viable C. albicans orf19.3906 ORF MRV6 CAL0002824 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient YPD medium C. albicans orf19.3906 ORF MRV6 CAL0002824 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient YNB medium C. albicans orf19.3908 ORF MRV8 CAL0002828 PMID: 24281718|CGD_REF: CAL0000173710 homozygous diploid, classical genetics null BWP17 viable C. albicans orf19.3908 ORF MRV8 CAL0002828 PMID: 24610660|CGD_REF: CAL0000173793 homozygous diploid, classical genetics null BWP17 viable C. albicans orf19.391 ORF UPC2 CAL0004944 PMID: 20041210|CGD_REF: CAL0124764 homozygous diploid, systematic mutation set null SN152 resistance to chemicals: decreased fluconazole severely sensitive C. albicans orf19.391 ORF UPC2 CAL0004944 PMID: 15590814|CGD_REF: CAL0082482 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased ketoconazole C. albicans orf19.391 ORF UPC2 CAL0004944 PMID: 15855491|CGD_REF: CAL0104089 heterozygous diploid, classical genetics overexpression Not recorded resistance to chemicals: increased ketoconazole C. albicans orf19.391 ORF UPC2 CAL0004944 PMID: 15590814|CGD_REF: CAL0082482 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased fenpropimorph C. albicans orf19.391 ORF UPC2 CAL0004944 PMID: 20041210|CGD_REF: CAL0124764 homozygous diploid, systematic mutation set null SN152 resistance to chemicals: decreased fenpropimorph strongly sensitive C. albicans orf19.391 ORF UPC2 CAL0004944 PMID: 15590814|CGD_REF: CAL0082482 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased itraconazole C. albicans orf19.391 ORF UPC2 CAL0004944 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.391 ORF UPC2 CAL0004944 PMID: 15590814|CGD_REF: CAL0082482 heterozygous diploid, classical genetics null Not recorded viable C. albicans orf19.391 ORF UPC2 CAL0004944 PMID: 15590814|CGD_REF: CAL0082482 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.391 ORF UPC2 CAL0004944 PMID: 15855491|CGD_REF: CAL0104089 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.391 ORF UPC2 CAL0004944 PMID: 19884367|CGD_REF: CAL0124528 homozygous diploid, classical genetics activation UPC2- (A643T) (hyperactive transcription factor) SC5314 resistance to chemicals: increased fluconazole hyperactivation causes constitutive induction of ERG11 C. albicans orf19.391 ORF UPC2 CAL0004944 PMID: 15855491|CGD_REF: CAL0104089 homozygous diploid, classical genetics null Not recorded anaerobic growth: decreased C. albicans orf19.391 ORF UPC2 CAL0004944 PMID: 15855491|CGD_REF: CAL0104089 heterozygous diploid, classical genetics overexpression Not recorded anaerobic growth: increased C. albicans orf19.391 ORF UPC2 CAL0004944 PMID: 18487346|CGD_REF: CAL0119007 heterozygous diploid, classical genetics unspecified upc2-G648D Not recorded resistance to chemicals: increased triazoles C. albicans orf19.391 ORF UPC2 CAL0004944 PMID: 15590814|CGD_REF: CAL0082482 homozygous diploid, classical genetics null Not recorded chemical compound accumulation: abnormal sterol ergosterol content and accumulation of lipophilic compounds are decreased C. albicans orf19.391 ORF UPC2 CAL0004944 PMID: 20041210|CGD_REF: CAL0124764 homozygous diploid, systematic mutation set null SN152 colony color: abnormal CHROMagar medium at 30 deg C darker than normal C. albicans orf19.391 ORF UPC2 CAL0004944 PMID: 15855491|CGD_REF: CAL0104089 heterozygous diploid, classical genetics overexpression Not recorded resistance to chemicals: increased fluphenazine C. albicans orf19.391 ORF UPC2 CAL0004944 PMID: 15855491|CGD_REF: CAL0104089 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased fluphenazine C. albicans orf19.391 ORF UPC2 CAL0004944 PMID: 15590814|CGD_REF: CAL0082482 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased terbinafine C. albicans orf19.391 ORF UPC2 CAL0004944 PMID: 15590814|CGD_REF: CAL0082482 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased lovastatin C. albicans orf19.391 ORF UPC2 CAL0004944 PMID: 15590814|CGD_REF: CAL0082482 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased fluconazole C. albicans orf19.391 ORF UPC2 CAL0004944 PMID: 15855491|CGD_REF: CAL0104089 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased fluconazole C. albicans orf19.391 ORF UPC2 CAL0004944 PMID: 15855491|CGD_REF: CAL0104089 heterozygous diploid, classical genetics overexpression Not recorded resistance to chemicals: increased fluconazole C. albicans orf19.391 ORF UPC2 CAL0004944 PMID: 24243794|CGD_REF: CAL0000173702 homozygous diploid, classical genetics gain of function UPC2-3 SC5314 virulence: decreased mouse intravenous infection C. albicans orf19.391 ORF UPC2 CAL0004944 PMID: 24376002|CGD_REF: CAL0000173742 homozygous diploid, classical genetics null SN152 induction of host response: decreased reduced levels of pyroptosis in macrophages C. albicans orf19.391 ORF UPC2 CAL0004944 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient SLAD medium C. albicans orf19.391 ORF UPC2 CAL0004944 PMID: 21078937|CGD_REF: CAL0139851 heterozygous diploid, classical genetics gain of function UPC2-A643V BWP17 resistance to chemicals: increased fluconazole C. albicans orf19.3910 ORF CAL0002852 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.3911 ORF SAH1 CAL0002855 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.3912 ORF GLN3 CAL0002857 PMID: 18547391|CGD_REF: CAL0119095 homozygous diploid, classical genetics null Not recorded utilization of nitrogen source: decreased bovine serum albumin as sole nitrogen source slight defect C. albicans orf19.3912 ORF GLN3 CAL0002857 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.3912 ORF GLN3 CAL0002857 PMID: 17369441|CGD_REF: CAL0117785 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.3912 ORF GLN3 CAL0002857 PMID: 17950010|CGD_REF: CAL0118825 homozygous diploid, classical genetics null Not recorded resistance to chemicals: increased rapamycin C. albicans orf19.3912 ORF GLN3 CAL0002857 PMID: 20041210|CGD_REF: CAL0124764 homozygous diploid, systematic mutation set null SN152 resistance to chemicals: increased rapamycin strongly resistant C. albicans orf19.3912 ORF GLN3 CAL0002857 PMID: 17950010|CGD_REF: CAL0118825 homozygous diploid, classical genetics null Not recorded utilization of nitrogen source: decreased urea C. albicans orf19.3912 ORF GLN3 CAL0002857 PMID: 17950010|CGD_REF: CAL0118825 homozygous diploid, classical genetics null Not recorded utilization of nitrogen source: decreased isoleucine C. albicans orf19.3912 ORF GLN3 CAL0002857 PMID: 20041210|CGD_REF: CAL0124764 homozygous diploid, systematic mutation set null SN152 resistance to chemicals: increased caffeine strongly resistant C. albicans orf19.3912 ORF GLN3 CAL0002857 PMID: 17950010|CGD_REF: CAL0118825 homozygous diploid, classical genetics null Not recorded utilization of nitrogen source: decreased glutamine C. albicans orf19.3912 ORF GLN3 CAL0002857 PMID: 17950010|CGD_REF: CAL0118825 homozygous diploid, classical genetics null Not recorded utilization of nitrogen source: decreased ammonium C. albicans orf19.3912 ORF GLN3 CAL0002857 PMID: 17950010|CGD_REF: CAL0118825 homozygous diploid, classical genetics null Not recorded utilization of nitrogen source: decreased arginine C. albicans orf19.3912 ORF GLN3 CAL0002857 PMID: 17369441|CGD_REF: CAL0117785 homozygous diploid, classical genetics null SC5314 filamentous growth: decreased nitrogen starvation C. albicans orf19.3912 ORF GLN3 CAL0002857 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.3912 ORF GLN3 CAL0002857 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.3912 ORF GLN3 CAL0002857 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.3912 ORF GLN3 CAL0002857 PMID: 17950010|CGD_REF: CAL0118825 homozygous diploid, classical genetics null Not recorded virulence: decreased mouse intravenous infection C. albicans orf19.3912 ORF GLN3 CAL0002857 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.3915 ORF CAL0002864 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.3919 ORF CAL0002874 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.3919 ORF CAL0002874 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.3919 ORF CAL0002874 PMID: 20494978|CGD_REF: CAL0125636 heterozygous diploid, classical genetics null BWP17 resistance to chemicals: decreased clotrimazole (75 uM) growth in liquid culture confirmation of mutant phenotypes for heterozygous transposon insertion strains showing sensitivity in a large-scale assay C. albicans orf19.3919 ORF CAL0002874 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.3919 ORF CAL0002874 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.3920 ORF CAL0002895 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.3921 ORF CAL0002896 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.3922 ORF CAL0002898 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.3923 ORF PGA37 CAL0002899 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.3923 ORF PGA37 CAL0002899 PMID: 18765290|CGD_REF: CAL0119430 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.3926 ORF RNY11 CAL0002906 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.3928 ORF CAL0002911 PMID: 15964282|CGD_REF: CAL0114274 homozygous diploid, systematic mutation set (split-marker transposon insertion strategy to disrupt both alleles) null BWP17 viable C. albicans orf19.3928 ORF CAL0002911 PMID: 15964282|CGD_REF: CAL0114274 homozygous diploid, systematic mutation set (split-marker transposon insertion strategy to disrupt both alleles) null BWP17 biofilm formation: normal C. albicans orf19.3928 ORF CAL0002911 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.3928 ORF CAL0002911 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.3928 ORF CAL0002911 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.3928 ORF CAL0002911 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.393 ORF APS3 CAL0004948 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.393 ORF APS3 CAL0004948 PMID: 20870878|CGD_REF: CAL0126471 homozygous diploid, classical genetics null aps3::ARG4/aps3::HIS1 BWP17 viable C. albicans orf19.393 ORF APS3 CAL0004948 PMID: 20870878|CGD_REF: CAL0126471 homozygous diploid, classical genetics null aps3::ARG4/aps3::HIS1 BWP17 vacuolar morphology: abnormal large vesicles accumulate within vacuole lumen C. albicans orf19.393 ORF APS3 CAL0004948 PMID: 20870878|CGD_REF: CAL0126471 homozygous diploid, classical genetics null aps3::ARG4/aps3::HIS1 BWP17 resistance to chemicals: decreased rapamycin C. albicans orf19.3930 ORF YUH2 CAL0002925 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, competitive growth (haploinsufficient phenotype assay, barcode deletion set) null SC5314 resistance to chemicals: decreased 5-fluorouracil C. albicans orf19.3930 ORF YUH2 CAL0002925 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.3931 ORF SFC1 CAL0002928 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.3932 ORF CAL0002930 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.3932 ORF CAL0002930 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient YPD medium C. albicans orf19.3932 ORF CAL0002930 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient SC medium C. albicans orf19.3934 ORF CAR1 CAL0002934 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.3936 ORF GDE1 CAL0002940 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, competitive growth (haploinsufficient phenotype assay, barcode deletion set) null SC5314 resistance to chemicals: decreased 5-fluorouracil C. albicans orf19.3936 ORF GDE1 CAL0002940 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.3936 ORF GDE1 CAL0002940 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.3936 ORF GDE1 CAL0002940 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.3936 ORF GDE1 CAL0002940 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.3936 ORF GDE1 CAL0002940 PMID: 24114876|CGD_REF: CAL0000173042 homozygous diploid, classical genetics null SC5314 chemical compound accumulation: increased glycerophosphocholine C. albicans orf19.3936 ORF GDE1 CAL0002940 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.3938 ORF CAL0002946 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, competitive growth (haploinsufficient phenotype assay, barcode deletion set) null SC5314 resistance to chemicals: decreased 5-fluorouracil C. albicans orf19.3938 ORF CAL0002946 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, competitive growth (haploinsufficient phenotype assay, barcode deletion set) null SC5314 resistance to chemicals: decreased tubercidin C. albicans orf19.3938 ORF CAL0002946 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, competitive growth (haploinsufficient phenotype assay, barcode deletion set) null SC5314 resistance to chemicals: decreased flucytosine C. albicans orf19.3938 ORF CAL0002946 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.3940.1 ORF CUP1 CAF0007430 PMID: 10737803|CGD_REF: CAL0081080 heterozygous diploid, classical genetics null cup1::hisG-URA3-hisG Other C. albicans metal resistance: normal copper C. albicans orf19.3940.1 ORF CUP1 CAF0007430 PMID: 10737803|CGD_REF: CAL0081080 heterozygous diploid, classical genetics null cup1::hisG-URA3-hisG Other C. albicans viable C. albicans orf19.3940.1 ORF CUP1 CAF0007430 PMID: 10737803|CGD_REF: CAL0081080 homozygous diploid, classical genetics null cup1::hisG-URA3-hisG/cup1::hisG Other C. albicans metal resistance: decreased copper slightly increased sensitivity to copper C. albicans orf19.3940.1 ORF CUP1 CAF0007430 PMID: 10737803|CGD_REF: CAL0081080 homozygous diploid, classical genetics null cup1::hisG-URA3-hisG/cup1::hisG Other C. albicans viable C. albicans orf19.3941 ORF URA7 CAL0002977 PMID: 21135205|CGD_REF: CAL0139967 heterozygous diploid, large-scale survey (large-scale identification of genes essential for virulence in mouse) repressible CAI-4 virulence: absent mouse intravenous infection C. albicans orf19.3942 ORF CAL0002978 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.3942.1 ORF RPL43A CAF0007000 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient YPD medium C. albicans orf19.3942.1 ORF RPL43A CAF0007000 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient SC medium C. albicans orf19.3942.1 ORF RPL43A CAF0007000 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient YNB medium C. albicans orf19.3942.1 ORF RPL43A CAF0007000 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient SLAD medium C. albicans orf19.3944 ORF GRR1 CAL0002979 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.3944 ORF GRR1 CAL0002979 PMID: 16730201|CGD_REF: CAL0116351 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.3944 ORF GRR1 CAL0002979 PMID: 16987179|CGD_REF: CAL0116690 homozygous diploid, classical genetics null Not recorded utilization of carbon source: decreased D-glucose C. albicans orf19.3944 ORF GRR1 CAL0002979 PMID: 16987179|CGD_REF: CAL0116690 homozygous diploid, classical genetics null Not recorded pseudohyphal growth: increased pseudohyphal growth is constitutive C. albicans orf19.3944 ORF GRR1 CAL0002979 PMID: 16730201|CGD_REF: CAL0116351 homozygous diploid, classical genetics null Not recorded pseudohyphal growth: abnormal pseudohyphal growth occurs under yeast-form growth-inducing conditions C. albicans orf19.3944 ORF GRR1 CAL0002979 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.3944 ORF GRR1 CAL0002979 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: abnormal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.3944 ORF GRR1 CAL0002979 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: decreased rate liquid synthetic complete medium C. albicans orf19.3944 ORF GRR1 CAL0002979 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient SLAD medium C. albicans orf19.3944 ORF GRR1 CAL0002979 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.3949 ORF CAL0002985 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.395 ORF ENO1 CAL0004953 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.395 ORF ENO1 CAL0004953 PMID: 16453178|CGD_REF: CAL0115982 heterozygous diploid, classical genetics repressible Not recorded viable C. albicans orf19.395 ORF ENO1 CAL0004953 PMID: 7896700|CGD_REF: CAL0081204 heterozygous diploid, classical genetics null Not recorded viable C. albicans orf19.395 ORF ENO1 CAL0004953 PMID: 16453178|CGD_REF: CAL0115982 heterozygous diploid, classical genetics repressible TR-ENO1/eno1::ARG4 BWP17 hyphal growth: absent serum-containing medium C. albicans orf19.395 ORF ENO1 CAL0004953 PMID: 14507372|CGD_REF: CAL0088818 heterozygous diploid, large-scale survey (large-scale identification of essential genes by gene replacement and conditional expression (GRACE) method) repressible CAI-4 inviable one allele is deleted and the other is placed under repressible Tet promoter C. albicans orf19.395 ORF ENO1 CAL0004953 PMID: 16453178|CGD_REF: CAL0115982 heterozygous diploid, classical genetics repressible Not recorded utilization of carbon source: absent glucose C. albicans orf19.395 ORF ENO1 CAL0004953 PMID: 23812815|CGD_REF: CAL0000172531 homozygous diploid, classical genetics null SC5314 resistance to chemicals: decreased amphotericin B C. albicans orf19.395 ORF ENO1 CAL0004953 PMID: 23812815|CGD_REF: CAL0000172531 homozygous diploid, classical genetics null SC5314 resistance to chemicals: decreased fluconazole C. albicans orf19.395 ORF ENO1 CAL0004953 PMID: 23812815|CGD_REF: CAL0000172531 homozygous diploid, classical genetics null SC5314 resistance to chemicals: decreased miconazole C. albicans orf19.395 ORF ENO1 CAL0004953 PMID: 23812815|CGD_REF: CAL0000172531 homozygous diploid, classical genetics null SC5314 resistance to chemicals: decreased voriconazole C. albicans orf19.395 ORF ENO1 CAL0004953 PMID: 23812815|CGD_REF: CAL0000172531 homozygous diploid, classical genetics null SC5314 virulence: decreased mouse intravenous infection C. albicans orf19.395 ORF ENO1 CAL0004953 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 invasive growth: decreased solid SLAD media C. albicans orf19.3950 ORF MSM1 CAL0003007 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.3951 ORF TIP1 CAL0003009 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.3951 ORF TIP1 CAL0003009 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, competitive growth (haploinsufficient phenotype assay, barcode deletion set) null SC5314 resistance to chemicals: decreased ergosterol analogs (ECC69 and/or ECC1384) C. albicans orf19.3951 ORF TIP1 CAL0003009 PMID: 21135205|CGD_REF: CAL0139967 heterozygous diploid, competitive growth (large-scale identification of genes essential for virulence in mouse) repressible CAI-4 virulence: decreased mouse intravenous infection C. albicans orf19.3952 ORF SRP101 CAL0003010 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.3954 ORF PSD2 CAL0003011 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.3954 ORF PSD2 CAL0003011 PMID: 20132453|CGD_REF: CAL0125003 homozygous diploid, classical genetics null psd2/psd2::SAT1-FLP SC5314 resistance to chemicals: increased papuamide B (5 micrograms/ml) C. albicans orf19.3954 ORF PSD2 CAL0003011 PMID: 20132453|CGD_REF: CAL0125003 homozygous diploid, classical genetics null psd2/psd2::SAT1-FLP SC5314 cold sensitivity: increased 37, 30 and 15 degrees C C. albicans orf19.3954 ORF PSD2 CAL0003011 PMID: 20132453|CGD_REF: CAL0125003 homozygous diploid, classical genetics null psd2/psd2::SAT1-FLP SC5314 resistance to chemicals: increased paraquat C. albicans orf19.3954 ORF PSD2 CAL0003011 PMID: 21135205|CGD_REF: CAL0139967 heterozygous diploid, competitive growth (large-scale identification of genes essential for virulence in mouse) repressible CAI-4 virulence: normal mouse intravenous infection C. albicans orf19.3955 ORF MES1 CAL0003012 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.3957 ORF CAL0003014 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.3959 ORF SSD1 CAL0003016 PMID: 18843050|CGD_REF: CAL0120345 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased Calcofluor White C. albicans orf19.3959 ORF SSD1 CAL0003016 PMID: 18515753|CGD_REF: CAL0119026 homozygous diploid, classical genetics null Not recorded toxin resistance: decreased human salivary histatin 5 C. albicans orf19.3959 ORF SSD1 CAL0003016 PMID: 18515753|CGD_REF: CAL0119026 homozygous diploid, classical genetics null Not recorded resistance to chemicals: normal sodium dodecyl sulfate C. albicans orf19.3959 ORF SSD1 CAL0003016 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.3959 ORF SSD1 CAL0003016 PMID: 18515753|CGD_REF: CAL0119026 homozygous diploid, classical genetics null BWP17 viable URA3 restored during strain construction C. albicans orf19.3959 ORF SSD1 CAL0003016 PMID: 18843050|CGD_REF: CAL0120345 heterozygous diploid, classical genetics null Not recorded viable URA3-blaster technique C. albicans orf19.3959 ORF SSD1 CAL0003016 PMID: 18843050|CGD_REF: CAL0120345 homozygous diploid, classical genetics null Not recorded viable URA3-blaster technique C. albicans orf19.3959 ORF SSD1 CAL0003016 PMID: 18515753|CGD_REF: CAL0119026 heterozygous diploid, classical genetics null Not recorded viable C. albicans orf19.3959 ORF SSD1 CAL0003016 PMID: 18515753|CGD_REF: CAL0119026 homozygous diploid, classical genetics null Not recorded oxidative stress resistance: normal hydrogen peroxide C. albicans orf19.3959 ORF SSD1 CAL0003016 PMID: 18515753|CGD_REF: CAL0119026 homozygous diploid, classical genetics null Not recorded resistance to chemicals: normal amphotericin B C. albicans orf19.3959 ORF SSD1 CAL0003016 PMID: 18843050|CGD_REF: CAL0120345 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased Congo Red C. albicans orf19.3959 ORF SSD1 CAL0003016 PMID: 18515753|CGD_REF: CAL0119026 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased protamine C. albicans orf19.3959 ORF SSD1 CAL0003016 PMID: 18515753|CGD_REF: CAL0119026 heterozygous diploid, classical genetics overexpression Not recorded resistance to chemicals: increased protamines C. albicans orf19.3959 ORF SSD1 CAL0003016 PMID: 18515753|CGD_REF: CAL0119026 homozygous diploid, classical genetics null Not recorded virulence: decreased mouse intravenous infection C. albicans orf19.3960 ORF HYS2 CAL0003049 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.3962 ORF HAS1 CAL0003050 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.3964 ORF ASH2 CAL0003052 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.3966 ORF CRH12 CAL0003054 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.3966 ORF CRH12 CAL0003054 PMID: 17074760|CGD_REF: CAL0117089 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.3966 ORF CRH12 CAL0003054 PMID: 17873081|CGD_REF: CAL0118685 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.3966 ORF CRH12 CAL0003054 PMID: 17074760|CGD_REF: CAL0117089 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased Congo Red C. albicans orf19.3966 ORF CRH12 CAL0003054 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.3966 ORF CRH12 CAL0003054 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.3966 ORF CRH12 CAL0003054 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.3966 ORF CRH12 CAL0003054 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.3967 ORF PFK1 CAL0003055 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.3969 ORF SFL2 CAL0003059 PMID: 20023067|CGD_REF: CAL0124775 homozygous diploid, classical genetics null SC5314 viable C. albicans orf19.3969 ORF SFL2 CAL0003059 PMID: 20023067|CGD_REF: CAL0124775 heterozygous diploid, classical genetics null SC5314 viable C. albicans orf19.3969 ORF SFL2 CAL0003059 PMID: 20023067|CGD_REF: CAL0124775 homozygous diploid, classical genetics null SC5314 invasive growth: absent embedded in YPSuc agar at 37 deg C C. albicans orf19.3969 ORF SFL2 CAL0003059 PMID: 20023067|CGD_REF: CAL0124775 homozygous diploid, classical genetics null SC5314 colony shape: abnormal Pal's or Spider agar colonies are smooth C. albicans orf19.3969 ORF SFL2 CAL0003059 PMID: 20023067|CGD_REF: CAL0124775 homozygous diploid, classical genetics null SC5314 vegetative growth: normal rate YPD medium at 37 deg C C. albicans orf19.3969 ORF SFL2 CAL0003059 PMID: 20023067|CGD_REF: CAL0124775 homozygous diploid, classical genetics null SC5314 virulence: normal organs carry a normal fungal burden, although almost no filamentous growth is observed in the kidney mouse intravenous infection C. albicans orf19.3969 ORF SFL2 CAL0003059 PMID: 20023067|CGD_REF: CAL0124775 heterozygous diploid, classical genetics null SC5314 invasive growth: decreased embedded in YPSuc agar at 37 deg C C. albicans orf19.3969 ORF SFL2 CAL0003059 PMID: 20023067|CGD_REF: CAL0124775 heterozygous diploid, classical genetics null SC5314 colony shape: abnormal Spider agar colonies are wrinkled, like wild-type, but lack the peripheral fringe of hyphae C. albicans orf19.3969 ORF SFL2 CAL0003059 PMID: 20023067|CGD_REF: CAL0124775 homozygous diploid, classical genetics overexpression SC5314 filamentous growth: increased liquid or solid YPD at 30 deg C filaments are formed under conditions normally promoting only yeast-form growth C. albicans orf19.3969 ORF SFL2 CAL0003059 PMID: 20023067|CGD_REF: CAL0124775 homozygous diploid, classical genetics null SC5314 germ tube formation: decreased 10% serum in the absence of preculture at 37 deg C C. albicans orf19.3969 ORF SFL2 CAL0003059 PMID: 20023067|CGD_REF: CAL0124775 homozygous diploid, classical genetics null SC5314 germ tube formation: absent 5% CO2 C. albicans orf19.3969 ORF SFL2 CAL0003059 PMID: 20023067|CGD_REF: CAL0124775 homozygous diploid, classical genetics null SC5314 germ tube formation: absent pH shift from 4.5 to 6.5 in Lee's medium C. albicans orf19.3969 ORF SFL2 CAL0003059 PMID: 20023067|CGD_REF: CAL0124775 heterozygous diploid, classical genetics null SC5314 germ tube formation: decreased pH shift from 4.5 to 6.5 in Lee's medium C. albicans orf19.3969 ORF SFL2 CAL0003059 PMID: 20023067|CGD_REF: CAL0124775 heterozygous diploid, classical genetics null SC5314 germ tube formation: decreased 5% CO2 C. albicans orf19.3969 ORF SFL2 CAL0003059 PMID: 20023067|CGD_REF: CAL0124775 homozygous diploid, classical genetics null SC5314 virulence: decreased reconstituted human epithelium capacity to damage human cells is decreased, and hyphal growth is not observed ex vivo model of infection C. albicans orf19.3969 ORF SFL2 CAL0003059 PMID: 20041210|CGD_REF: CAL0124764 homozygous diploid, systematic mutation set null SN152 colony appearance: abnormal Spider medium reduced colony wrinkling C. albicans orf19.3969 ORF SFL2 CAL0003059 PMID: 21205158|CGD_REF: CAL0140095 homozygous diploid, classical genetics null sfl2::hisG/sfl2::hisG-URA3-hisG CAI-4 viable C. albicans orf19.3969 ORF SFL2 CAL0003059 PMID: 21205158|CGD_REF: CAL0140095 homozygous diploid, classical genetics null sfl2::hisG/sfl2::hisG-URA3-hisG CAI-4 hyphal growth: decreased C. albicans orf19.3969 ORF SFL2 CAL0003059 PMID: 21205158|CGD_REF: CAL0140095 homozygous diploid, classical genetics null sfl2::hisG/sfl2::hisG-URA3-hisG CAI-4 virulence: decreased mouse gastrointestinal tract infection C. albicans orf19.397 ORF CAL0004959 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.3970 ORF CAL0003091 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.3972 ORF CAL0003094 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.3972 ORF CAL0003094 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 invasive growth: decreased solid SLAD media C. albicans orf19.3980 ORF CAL0003134 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.3980 ORF CAL0003134 PMID: 20494978|CGD_REF: CAL0125636 heterozygous diploid, classical genetics null BWP17 resistance to chemicals: decreased clotrimazole (75 uM) growth in liquid culture confirmation of mutant phenotypes for heterozygous transposon insertion strains showing sensitivity in a large-scale assay C. albicans orf19.3981 ORF MAL31 CAL0003136 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.3982 ORF CAL0003137 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.3982 ORF CAL0003137 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.3982 ORF CAL0003137 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.3982 ORF CAL0003137 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.3982 ORF CAL0003137 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.3983 ORF CAL0003138 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.3986 ORF PPR1 CAL0003140 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.3986 ORF PPR1 CAL0003140 PMID: 15964282|CGD_REF: CAL0114274 homozygous diploid, systematic mutation set (split-marker transposon insertion strategy to disrupt both alleles) null BWP17 viable C. albicans orf19.3986 ORF PPR1 CAL0003140 PMID: 19463063|CGD_REF: CAL0123630 homozygous diploid, systematic mutation set (split-marker transposon insertion strategy to disrupt both alleles) null BWP17 viable C. albicans orf19.3986 ORF PPR1 CAL0003140 PMID: 15964282|CGD_REF: CAL0114274 homozygous diploid, systematic mutation set (split-marker transposon insertion strategy to disrupt both alleles) null BWP17 biofilm formation: normal C. albicans orf19.3986 ORF PPR1 CAL0003140 PMID: 22073120|CGD_REF: CAL0000143592 homozygous diploid, classical genetics null BWP17 hyphal growth: decreased C. albicans orf19.3986 ORF PPR1 CAL0003140 PMID: 19463063|CGD_REF: CAL0123630 homozygous diploid, systematic mutation set (split-marker transposon insertion strategy to disrupt both alleles) null BWP17 virulence: normal Toll mutant D. melanogaster invasive infection insect infection C. albicans orf19.399 ORF CAL0004967 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.3990 ORF CAL0003169 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.3991 ORF CAL0003171 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.3994 ORF CAL0003173 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.3995 ORF RIM13 CAL0003174 PMID: 12819929|CGD_REF: CAL0081778 homozygous diploid, classical genetics null Not recorded vegetative growth: decreased rate alkaline pH C. albicans orf19.3995 ORF RIM13 CAL0003174 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.3995 ORF RIM13 CAL0003174 PMID: 12524333|CGD_REF: CAL0080691 homozygous diploid, systematic mutation set (homozygous insertion mutants generated with URA3-ARG4-URA3 (UAU1) cassette) null BWP17 viable C. albicans orf19.3995 ORF RIM13 CAL0003174 PMID: 14663094|CGD_REF: CAL0080633 homozygous diploid, systematic mutation set (homozygous insertion mutants generated with URA3-ARG4-URA3 (UAU1) cassette) null BWP17 viable C. albicans orf19.3995 ORF RIM13 CAL0003174 PMID: 12819929|CGD_REF: CAL0081778 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.3995 ORF RIM13 CAL0003174 PMID: 15590834|CGD_REF: CAL0082485 homozygous diploid, classical genetics null Not recorded protein/peptide modification: absent Rim101p is not processed Rim101p C. albicans orf19.3995 ORF RIM13 CAL0003174 PMID: 12524333|CGD_REF: CAL0080691 homozygous diploid, systematic mutation set (homozygous insertion mutants generated with URA3-ARG4-URA3 (UAU1) cassette) null BWP17 hyphal growth: abnormal defective alkaline ph-induced hyphal growth C. albicans orf19.3995 ORF RIM13 CAL0003174 PMID: 14663094|CGD_REF: CAL0080633 homozygous diploid, systematic mutation set (homozygous insertion mutants generated with URA3-ARG4-URA3 (UAU1) cassette) null BWP17 hyphal growth: decreased embedded in solid medium C. albicans orf19.3995 ORF RIM13 CAL0003174 PMID: 18836025|CGD_REF: CAL0120344 homozygous diploid, classical genetics null Not recorded chemical compound accumulation: decreased phenethyl alcohol C. albicans orf19.3995 ORF RIM13 CAL0003174 PMID: 18836025|CGD_REF: CAL0120344 homozygous diploid, classical genetics null Not recorded chemical compound accumulation: decreased tyrosol C. albicans orf19.3995 ORF RIM13 CAL0003174 PMID: 14663094|CGD_REF: CAL0080633 homozygous diploid, systematic mutation set (homozygous insertion mutants generated with URA3-ARG4-URA3 (UAU1) cassette) null BWP17 chlamydospore formation: decreased C. albicans orf19.3995 ORF RIM13 CAL0003174 PMID: 18836025|CGD_REF: CAL0120344 homozygous diploid, classical genetics null Not recorded chemical compound accumulation: decreased tryptophol C. albicans orf19.3995 ORF RIM13 CAL0003174 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: decreased growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.3995 ORF RIM13 CAL0003174 PMID: 22427429|CGD_REF: CAL0000156990 homozygous diploid, classical genetics null BWP17 protein/peptide modification: absent mutants don't process RIM8-HA RIM8-HA C. albicans orf19.3995 ORF RIM13 CAL0003174 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: abnormal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.3995 ORF RIM13 CAL0003174 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, classical genetics null SN152 germ tube formation: decreased serum-containing medium C. albicans orf19.3995 ORF RIM13 CAL0003174 PMID: 17241762|CGD_REF: CAL0117323 homozygous diploid, classical genetics null Not recorded virulence: decreased mouse corneal infection C. albicans orf19.3995 ORF RIM13 CAL0003174 PMID: 17251477|CGD_REF: CAL0117217 homozygous diploid, classical genetics null Not recorded virulence: absent mouse corneal infection C. albicans orf19.3995 ORF RIM13 CAL0003174 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.3995 ORF RIM13 CAL0003174 PMID: 20375342|CGD_REF: CAL0125177 homozygous diploid, classical genetics null BWP17 virulence: decreased BALB/C mice mouse corneal infection C. albicans orf19.3995 ORF RIM13 CAL0003174 PMID: 20375342|CGD_REF: CAL0125177 homozygous diploid, classical genetics null BWP17 invasive growth: decreased porcine corneal tissue depth of hyphal penetration into corneal tissue is reduced ex vivo model of infection C. albicans orf19.3995 ORF RIM13 CAL0003174 PMID: 20375342|CGD_REF: CAL0125177 homozygous diploid, classical genetics null BWP17 filamentous growth: absent solid M199 medium pH 7.3 or 8.0 C. albicans orf19.3995 ORF RIM13 CAL0003174 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.3996 ORF CAL0003175 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.3997 ORF ADH1 CAL0003176 PMID: 16790752|CGD_REF: CAL0116201 homozygous diploid, classical genetics null BWP17 viable C. albicans orf19.3997 ORF ADH1 CAL0003176 PMID: 16790752|CGD_REF: CAL0116201 homozygous diploid, classical genetics null BWP17 biofilm formation: increased C. albicans orf19.3997 ORF ADH1 CAL0003176 PMID: 16790752|CGD_REF: CAL0116201 heterozygous diploid, classical genetics null BWP17 biofilm formation: increased C. albicans orf19.3997 ORF ADH1 CAL0003176 PMID: 24607541|CGD_REF: CAL0000173787 homozygous diploid, classical genetics null SC5314 vegetative growth: decreased rate C. albicans orf19.3997 ORF ADH1 CAL0003176 PMID: 24607541|CGD_REF: CAL0000173787 homozygous diploid, classical genetics null SC5314 resistance to chemicals: decreased tert-butyl hydroperoxide (0.5 mM) C. albicans orf19.3997 ORF ADH1 CAL0003176 PMID: 24607541|CGD_REF: CAL0000173787 homozygous diploid, classical genetics null SC5314 resistance to chemicals: decreased 1,1'-azobis(N,N-dimethylformamide) (0.5 mM) C. albicans orf19.3997 ORF ADH1 CAL0003176 PMID: 24607541|CGD_REF: CAL0000173787 homozygous diploid, classical genetics null SC5314 oxidative stress resistance: decreased hydrogen peroxide (0.5 mM) C. albicans orf19.3997 ORF ADH1 CAL0003176 PMID: 24607541|CGD_REF: CAL0000173787 homozygous diploid, classical genetics null SC5314 oxidative stress resistance: decreased menadione (0.5 mM) C. albicans orf19.3997 ORF ADH1 CAL0003176 PMID: 24607541|CGD_REF: CAL0000173787 homozygous diploid, classical genetics null SC5314 virulence: decreased mouse intravenous infection C. albicans orf19.400 ORF GCF1 CAL0005535 PMID: 19332824|CGD_REF: CAL0122661 homozygous diploid, classical genetics null Not recorded inviable homozygous null mutant strain could not be recovered, suggesting that the gene is essential under the selection conditions C. albicans orf19.400 ORF GCF1 CAL0005535 PMID: 19332824|CGD_REF: CAL0122661 heterozygous diploid, classical genetics repressible Not recorded mitochondrial genome maintenance: abnormal decreased mitochondrial DNA content C. albicans orf19.400 ORF GCF1 CAL0005535 PMID: 19332824|CGD_REF: CAL0122661 heterozygous diploid, classical genetics overexpression Not recorded mitochondrial genome maintenance: abnormal increased mitochondrial DNA content C. albicans orf19.4000 ORF GRF10 CAL0004635 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.4000 ORF GRF10 CAL0004635 PMID: 22253901|CGD_REF: CAL0000143881 homozygous diploid, classical genetics null BWP17 viable C. albicans orf19.4000 ORF GRF10 CAL0004635 PMID: 22253901|CGD_REF: CAL0000143881 homozygous diploid, classical genetics null BWP17 filamentous growth: decreased phosphate limitation C. albicans orf19.4001 ORF CAL0004638 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.4001 ORF CAL0004638 PMID: 23856128|CGD_REF: CAL0000172540 homozygous diploid, classical genetics null BWP17 resistance to chemicals: decreased propolis C. albicans orf19.4002 ORF DUN1 CAL0004640 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.4002 ORF DUN1 CAL0004640 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: decreased growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.4002 ORF DUN1 CAL0004640 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.4002 ORF DUN1 CAL0004640 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.4002 ORF DUN1 CAL0004640 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.4003 ORF TIP20 CAL0004642 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.4003 ORF TIP20 CAL0004642 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 invasive growth: decreased solid SLAD media C. albicans orf19.4004 ORF CCT3 CAL0004644 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.4004 ORF CCT3 CAL0004644 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, competitive growth (haploinsufficient phenotype assay, barcode deletion set) null SC5314 resistance to chemicals: decreased cytochalasin D C. albicans orf19.4005 ORF CAL0004646 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.4005 ORF CAL0004646 PMID: 12524333|CGD_REF: CAL0080691 homozygous diploid, systematic mutation set (homozygous insertion mutants generated with URA3-ARG4-URA3 (UAU1) cassette) null BWP17 inviable homozygous null mutant strain could not be recovered, suggesting that the gene is essential under the selection conditions C. albicans orf19.4005 ORF CAL0004646 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient YPD medium C. albicans orf19.4006 ORF CAL0004648 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.4007 ORF CAL0004649 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.4009 ORF CNB1 CAL0004650 PMID: 15557662|CGD_REF: CAL0082138 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased lithium chloride C. albicans orf19.4009 ORF CNB1 CAL0004650 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.4009 ORF CNB1 CAL0004650 PMID: 11847103|CGD_REF: CAL0081043 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.4009 ORF CNB1 CAL0004650 PMID: 12796287|CGD_REF: CAL0081044 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.4009 ORF CNB1 CAL0004650 PMID: 15557662|CGD_REF: CAL0082138 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.4009 ORF CNB1 CAL0004650 PMID: 17927701|CGD_REF: CAL0118690 homozygous diploid, classical genetics null Not recorded acid pH resistance: decreased pH 2 C. albicans orf19.4009 ORF CNB1 CAL0004650 PMID: 18180354|CGD_REF: CAL0118822 homozygous diploid, classical genetics null SC5314 biofilm formation: normal C. albicans orf19.4009 ORF CNB1 CAL0004650 PMID: 16113294|CGD_REF: CAL0114615 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased calcium(2+) physiological calcium concentrations in serum account for the toxicity of serum against this mutant C. albicans orf19.4009 ORF CNB1 CAL0004650 PMID: 19649312|CGD_REF: CAL0123929 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased micafungin (30 ng/ml) micafungin treatment is fungicidal C. albicans orf19.4009 ORF CNB1 CAL0004650 PMID: 11847103|CGD_REF: CAL0081043 heterozygous diploid, classical genetics gain of function Not recorded resistance to chemicals: increased FK506 resistance is dominant C. albicans orf19.4009 ORF CNB1 CAL0004650 PMID: 11847103|CGD_REF: CAL0081043 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased triazoles C. albicans orf19.4009 ORF CNB1 CAL0004650 PMID: 15557662|CGD_REF: CAL0082138 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased fluconazole C. albicans orf19.4009 ORF CNB1 CAL0004650 PMID: 16923949|CGD_REF: CAL0116864 homozygous diploid, classical genetics null Not recorded virulence: decreased accelerated disease resolution mouse corneal infection C. albicans orf19.4009 ORF CNB1 CAL0004650 PMID: 12796287|CGD_REF: CAL0081044 homozygous diploid, classical genetics null Not recorded virulence: decreased exhibits no kidney colonization mouse intravenous infection C. albicans orf19.4009 ORF CNB1 CAL0004650 PMID: 15557662|CGD_REF: CAL0082138 homozygous diploid, classical genetics null Not recorded virulence: absent mouse intravenous infection C. albicans orf19.4009 ORF CNB1 CAL0004650 PMID: 20870881|CGD_REF: CAL0126465 homozygous diploid, classical genetics null SC5314 cell death: increased C. albicans orf19.401 ORF TCP1 CAL0005536 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.4010 ORF PAN3 CAL0004671 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.4010 ORF PAN3 CAL0004671 PMID: 14663094|CGD_REF: CAL0080633 homozygous diploid, systematic mutation set (homozygous insertion mutants generated with URA3-ARG4-URA3 (UAU1) cassette) null BWP17 viable C. albicans orf19.4011 ORF CAL0004674 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.4011 ORF CAL0004674 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.4011 ORF CAL0004674 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.4011 ORF CAL0004674 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.4012 ORF PCL5 CAL0004676 PMID: 15701793|CGD_REF: CAL0082332 homozygous diploid, classical genetics null CAI-4 germ tube formation: decreased liquid Lee's medium C. albicans orf19.4012 ORF PCL5 CAL0004676 PMID: 15701793|CGD_REF: CAL0082332 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.4012 ORF PCL5 CAL0004676 PMID: 15701793|CGD_REF: CAL0082332 homozygous diploid, classical genetics null CAI-4 filamentous growth: decreased solid Lee's medium C. albicans orf19.4012 ORF PCL5 CAL0004676 PMID: 15701793|CGD_REF: CAL0082332 homozygous diploid, classical genetics null Not recorded resistance to chemicals: increased 3-aminotriazole C. albicans orf19.4012 ORF PCL5 CAL0004676 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.4012 ORF PCL5 CAL0004676 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.4012 ORF PCL5 CAL0004676 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.4012 ORF PCL5 CAL0004676 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient YPD medium C. albicans orf19.4012 ORF PCL5 CAL0004676 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.4014 ORF CAL0004680 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.4014 ORF CAL0004680 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: abnormal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.4014 ORF CAL0004680 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.4014 ORF CAL0004680 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.4015 ORF CAG1 CAL0004682 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.4015 ORF CAG1 CAL0004682 PMID: 14507372|CGD_REF: CAL0088818 heterozygous diploid, large-scale survey (large-scale identification of essential genes by gene replacement and conditional expression (GRACE) method) repressible CAI-4 viable one allele is deleted and the other is placed under repressible Tet promoter C. albicans orf19.4015 ORF CAG1 CAL0004682 PMID: 1569935|CGD_REF: CAL0082132 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.4015 ORF CAG1 CAL0004682 PMID: 18658257|CGD_REF: CAL0119356 heterozygous diploid, classical genetics null Not recorded viable C. albicans orf19.4015 ORF CAG1 CAL0004682 PMID: 18658257|CGD_REF: CAL0119356 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.4015 ORF CAG1 CAL0004682 PMID: 18658257|CGD_REF: CAL0119356 heterozygous diploid, classical genetics overexpression Not recorded viable C. albicans orf19.4015 ORF CAG1 CAL0004682 PMID: 1569935|CGD_REF: CAL0082132 heterozygous diploid, classical genetics null WO-1 hyphal growth: normal serum-containing medium C. albicans orf19.4015 ORF CAG1 CAL0004682 PMID: 1569935|CGD_REF: CAL0082132 homozygous diploid, classical genetics null WO-1 hyphal growth: normal serum-containing medium C. albicans orf19.4015 ORF CAG1 CAL0004682 PMID: 18658257|CGD_REF: CAL0119356 homozygous diploid, classical genetics null Not recorded mating response: absent C. albicans orf19.4015 ORF CAG1 CAL0004682 PMID: 18658257|CGD_REF: CAL0119356 homozygous diploid, classical genetics null Not recorded pheromone sensitivity: decreased alpha factor mating projection not formed C. albicans orf19.4015 ORF CAG1 CAL0004682 PMID: 18658257|CGD_REF: CAL0119356 heterozygous diploid, classical genetics overexpression Not recorded pheromone-induced cell cycle arrest: normal C. albicans orf19.4015 ORF CAG1 CAL0004682 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.4015 ORF CAG1 CAL0004682 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.4015 ORF CAG1 CAL0004682 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.4015 ORF CAG1 CAL0004682 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.4015 ORF CAG1 CAL0004682 PMID: 21135205|CGD_REF: CAL0139967 heterozygous diploid, competitive growth (large-scale identification of genes essential for virulence in mouse) repressible CAI-4 virulence: normal mouse intravenous infection C. albicans orf19.4016 ORF CAL0004684 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.4023 ORF MRP2 CAL0004723 PMID: 12773383|CGD_REF: CAL0087974 heterozygous diploid, classical genetics (haploinsufficient phenotype assay) null CAI-4 viable heterozygous transposon insertion C. albicans orf19.4023 ORF MRP2 CAL0004723 PMID: 12773383|CGD_REF: CAL0087974 heterozygous diploid, classical genetics (haploinsufficient phenotype assay) null CAI-4 filamentous growth: decreased solid Spider medium or solid YEPD plus serum different alleles affect filamentous growth on different media; heterozygous transposon mutant alleles C. albicans orf19.4024 ORF RIB5 CAL0004725 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.4024 ORF RIB5 CAL0004725 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient YPD medium C. albicans orf19.4025 ORF PRE1 CAL0004727 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.4025 ORF PRE1 CAL0004727 PMID: 21135205|CGD_REF: CAL0139967 heterozygous diploid, large-scale survey (large-scale identification of genes essential for virulence in mouse) repressible CAI-4 virulence: absent mouse intravenous infection C. albicans orf19.4026 ORF HIS1 CAL0004729 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.4026 ORF HIS1 CAL0004729 PMID: 14507372|CGD_REF: CAL0088818 heterozygous diploid, large-scale survey (large-scale identification of essential genes by gene replacement and conditional expression (GRACE) method) repressible CAI-4 inviable one allele is deleted and the other is placed under repressible Tet promoter C. albicans orf19.4026 ORF HIS1 CAL0004729 PMID: 7489899|CGD_REF: CAL0081377 unknown ploidy, classical genetics unspecified Other C. albicans viable C. albicans orf19.4026 ORF HIS1 CAL0004729 PMID: 7489899|CGD_REF: CAL0081377 unknown ploidy, classical genetics unspecified Other C. albicans auxotrophy histidine C. albicans orf19.4026 ORF HIS1 CAL0004729 PMID: 20737428|CGD_REF: CAL0126182 homozygous diploid, classical genetics null SC5314 viable phenotype is also observed in the WO-1 background C. albicans orf19.4026 ORF HIS1 CAL0004729 PMID: 20737428|CGD_REF: CAL0126182 homozygous diploid, classical genetics null SC5314 auxotrophy histidine phenotype is also observed in the WO-1 background C. albicans orf19.4028 ORF CAL0004730 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.4029 ORF CAL0004731 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.4029 ORF CAL0004731 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient YPD medium C. albicans orf19.403 ORF PCL2 CAL0005537 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.403 ORF PCL2 CAL0005537 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.403 ORF PCL2 CAL0005537 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.403 ORF PCL2 CAL0005537 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.403 ORF PCL2 CAL0005537 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.4030 ORF CAL0004759 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.4031 ORF CAL0004763 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.4032 ORF RPN5 CAL0004766 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.4033 ORF PRP22 CAL0004768 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.4035 ORF PGA4 CAL0004772 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.4035 ORF PGA4 CAL0004772 PMID: 17257864|CGD_REF: CAL0117713 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.4035 ORF PGA4 CAL0004772 PMID: 18765290|CGD_REF: CAL0119430 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.4035 ORF PGA4 CAL0004772 PMID: 18765290|CGD_REF: CAL0119430 homozygous diploid, classical genetics null Not recorded cell wall morphology: abnormal increased thickness C. albicans orf19.4035 ORF PGA4 CAL0004772 PMID: 18765290|CGD_REF: CAL0119430 homozygous diploid, classical genetics null Not recorded resistance to chemicals: increased caspofungin C. albicans orf19.4035 ORF PGA4 CAL0004772 PMID: 18765290|CGD_REF: CAL0119430 homozygous diploid, classical genetics null Not recorded chemical compound accumulation: increased glucan increased cell wall glucan C. albicans orf19.4035 ORF PGA4 CAL0004772 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.4035 ORF PGA4 CAL0004772 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.4035 ORF PGA4 CAL0004772 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.4035 ORF PGA4 CAL0004772 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.4036 ORF APM1 CAL0004774 PMID: 12773383|CGD_REF: CAL0087974 heterozygous diploid, classical genetics (haploinsufficient phenotype assay) null CAI-4 viable heterozygous transposon insertion C. albicans orf19.4036 ORF APM1 CAL0004774 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.4036 ORF APM1 CAL0004774 PMID: 12773383|CGD_REF: CAL0087974 heterozygous diploid, classical genetics (haploinsufficient phenotype assay) null CAI-4 filamentous growth: increased solid Spider medium heterozygous transposon insertion C. albicans orf19.4036 ORF APM1 CAL0004774 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.4036 ORF APM1 CAL0004774 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: abnormal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.4036 ORF APM1 CAL0004774 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.4036 ORF APM1 CAL0004774 PMID: 20494978|CGD_REF: CAL0125636 heterozygous diploid, classical genetics null BWP17 resistance to chemicals: decreased clotrimazole (75 uM) growth in liquid culture confirmation of mutant phenotypes for heterozygous transposon insertion strains showing sensitivity in a large-scale assay C. albicans orf19.4036 ORF APM1 CAL0004774 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.4040 ORF ILV3 CAL0004803 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.4041 ORF PEX4 CAL0004806 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.4041 ORF PEX4 CAL0004806 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.4041 ORF PEX4 CAL0004806 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.4041 ORF PEX4 CAL0004806 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.4045 ORF EST1 CAL0004815 PMID: 12477797|CGD_REF: CAL0081268 homozygous diploid, classical genetics null Not recorded telomere length: decreased C. albicans orf19.4045 ORF EST1 CAL0004815 PMID: 16714448|CGD_REF: CAL0116045 homozygous diploid, classical genetics null Not recorded telomere length: decreased C. albicans orf19.4045 ORF EST1 CAL0004815 PMID: 17545315|CGD_REF: CAL0118239 homozygous diploid, classical genetics null Not recorded telomere length: decreased C. albicans orf19.4045 ORF EST1 CAL0004815 PMID: 12477797|CGD_REF: CAL0081268 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.4045 ORF EST1 CAL0004815 PMID: 12716976|CGD_REF: CAL0081269 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.4045 ORF EST1 CAL0004815 PMID: 16714448|CGD_REF: CAL0116045 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.4045 ORF EST1 CAL0004815 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient YPD medium C. albicans orf19.4045 ORF EST1 CAL0004815 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient SLAD medium C. albicans orf19.4048 ORF DES1 CAL0004818 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.405 ORF VCX1 CAL0005539 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.4051 ORF HTS1 CAL0004839 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.4055 ORF CAL0004847 PMID: 12773383|CGD_REF: CAL0087974 heterozygous diploid, classical genetics (haploinsufficient phenotype assay) null CAI-4 viable heterozygous transposon insertion C. albicans orf19.4055 ORF CAL0004847 PMID: 12773383|CGD_REF: CAL0087974 heterozygous diploid, classical genetics (haploinsufficient phenotype assay) null CAI-4 filamentous growth: increased solid Spider medium heterozygous transposon insertion C. albicans orf19.4056 ORF BRG1 CAL0004848 PMID: 22757963|CGD_REF: CAL0000157562 aneuploid, classical genetics overexpression SC5314 colony shape: abnormal wrinkled colonies C. albicans orf19.4056 ORF BRG1 CAL0004848 PMID: 22757963|CGD_REF: CAL0000157562 aneuploid, classical genetics overexpression SC5314 invasive growth: increased C. albicans orf19.4056 ORF BRG1 CAL0004848 PMID: 22757963|CGD_REF: CAL0000157562 aneuploid, classical genetics overexpression SC5314 hyphal growth: increased C. albicans orf19.4056 ORF BRG1 CAL0004848 PMID: 22757963|CGD_REF: CAL0000157562 aneuploid, classical genetics overexpression SC5314 biofilm formation: increased C. albicans orf19.4056 ORF BRG1 CAL0004848 PMID: 22757963|CGD_REF: CAL0000157562 aneuploid, classical genetics overexpression SC5314 virulence: decreased mouse intravenous infection C. albicans orf19.4056 ORF BRG1 CAL0004848 PMID: 20041210|CGD_REF: CAL0124764 homozygous diploid, systematic mutation set null SN152 invasive growth: decreased YEPD medium at 30 deg C; SD or YEPD media at 37 deg C strongly decreased C. albicans orf19.4056 ORF BRG1 CAL0004848 PMID: 20041210|CGD_REF: CAL0124764 homozygous diploid, systematic mutation set null SN152 colony appearance: abnormal Spider medium smooth colonies with no peripheral filamentation C. albicans orf19.4056 ORF BRG1 CAL0004848 PMID: 12773383|CGD_REF: CAL0087974 heterozygous diploid, classical genetics (haploinsufficient phenotype assay) unspecified CAI-4 filamentous growth: increased solid Spider medium or solid YEPD plus serum transposon insertion proximal to, but not within, the ORF C. albicans orf19.4056 ORF BRG1 CAL0004848 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.4056 ORF BRG1 CAL0004848 PMID: 22265407|CGD_REF: CAL0000143925 homozygous diploid, classical genetics null Other C. albicans biofilm formation: abnormal C. albicans orf19.4056 ORF BRG1 CAL0004848 PMID: 22276126|CGD_REF: CAL0000143926 homozygous diploid, classical genetics null Other C. albicans filamentous growth: decreased C. albicans orf19.4056 ORF BRG1 CAL0004848 PMID: 22276126|CGD_REF: CAL0000143926 homozygous diploid, classical genetics null Other C. albicans virulence: decreased mouse intravenous infection C. albicans orf19.4056 ORF BRG1 CAL0004848 PMID: 22276126|CGD_REF: CAL0000143926 aneuploid, classical genetics overexpression Other C. albicans filamentous growth: increased C. albicans orf19.4056 ORF BRG1 CAL0004848 PMID: 22276126|CGD_REF: CAL0000143926 homozygous diploid, classical genetics null Other C. albicans biofilm formation: abnormal C. albicans orf19.4056 ORF BRG1 CAL0004848 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: abnormal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.4056 ORF BRG1 CAL0004848 PMID: 23637598|CGD_REF: CAL0000172002 homozygous diploid, classical genetics null arg1::hisG/arg1::hisG brg1::HIS1/brg1::LEU2 SC5314 biofilm formation: decreased 37 degrees C in Spider medium 24 h or 60 h with gentle shaking C. albicans orf19.4056 ORF BRG1 CAL0004848 PMID: 23637598|CGD_REF: CAL0000172002 homozygous diploid, classical genetics null a/a arg::hisG/arg::hisG brg1::HIS1/brg1::LEU2 P37005 biofilm formation: decreased 37 degrees C in Spider medium deficient in 10uM alpha pheromone stimulated biofilms C. albicans orf19.4056 ORF BRG1 CAL0004848 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.4056 ORF BRG1 CAL0004848 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.4059 ORF CAL0004850 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.406 ORF ERG1 CAL0005541 PMID: 16246085|CGD_REF: CAL0114864 heterozygous diploid, classical genetics repressible Not recorded resistance to chemicals: decreased ketoconazole C. albicans orf19.406 ORF ERG1 CAL0005541 PMID: 15845783|CGD_REF: CAL0114245 heterozygous diploid, classical genetics repressible Not recorded vegetative growth: decreased rate one allele under the control of the MET3 regulatable promoter C. albicans orf19.406 ORF ERG1 CAL0005541 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.406 ORF ERG1 CAL0005541 PMID: 16246085|CGD_REF: CAL0114864 heterozygous diploid, classical genetics null Not recorded viable C. albicans orf19.406 ORF ERG1 CAL0005541 PMID: 16246085|CGD_REF: CAL0114864 heterozygous diploid, classical genetics repressible Not recorded viable C. albicans orf19.406 ORF ERG1 CAL0005541 PMID: 16607011|CGD_REF: CAL0115846 heterozygous diploid, classical genetics null Not recorded viable C. albicans orf19.406 ORF ERG1 CAL0005541 PMID: 16246085|CGD_REF: CAL0114864 heterozygous diploid, classical genetics repressible Not recorded protein transport: abnormal decreased cell-surface localization of Cdr1p Cdr1p C. albicans orf19.406 ORF ERG1 CAL0005541 PMID: 16246085|CGD_REF: CAL0114864 heterozygous diploid, classical genetics conditional CAF2-1 hyphal growth: decreased solid Spider or liquid GlcNAc plus serum media C. albicans orf19.406 ORF ERG1 CAL0005541 PMID: 16246085|CGD_REF: CAL0114864 homozygous diploid, classical genetics null Not recorded inviable homozygous null mutant strain could not be recovered, suggesting that the gene is essential under the selection conditions C. albicans orf19.406 ORF ERG1 CAL0005541 PMID: 16607011|CGD_REF: CAL0115846 homozygous diploid, classical genetics null Not recorded inviable homozygous null mutant strain could not be recovered, suggesting that the gene is essential under the selection conditions C. albicans orf19.406 ORF ERG1 CAL0005541 PMID: 15845783|CGD_REF: CAL0114245 homozygous diploid, classical genetics null Not recorded inviable C. albicans orf19.406 ORF ERG1 CAL0005541 PMID: 16607011|CGD_REF: CAL0115846 heterozygous diploid, classical genetics repressible SC5314 inviable C. albicans orf19.406 ORF ERG1 CAL0005541 PMID: 16246085|CGD_REF: CAL0114864 heterozygous diploid, classical genetics repressible Not recorded resistance to chemicals: decreased amphotericin B C. albicans orf19.406 ORF ERG1 CAL0005541 PMID: 16246085|CGD_REF: CAL0114864 heterozygous diploid, classical genetics repressible Not recorded resistance to chemicals: decreased cycloheximide C. albicans orf19.406 ORF ERG1 CAL0005541 PMID: 16246085|CGD_REF: CAL0114864 heterozygous diploid, classical genetics repressible Not recorded resistance to chemicals: decreased nystatin C. albicans orf19.406 ORF ERG1 CAL0005541 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, competitive growth (haploinsufficient phenotype assay, barcode deletion set) null SC5314 resistance to chemicals: decreased terbinafine C. albicans orf19.406 ORF ERG1 CAL0005541 PMID: 16246085|CGD_REF: CAL0114864 heterozygous diploid, classical genetics repressible Not recorded resistance to chemicals: decreased terbinafine C. albicans orf19.406 ORF ERG1 CAL0005541 PMID: 16607011|CGD_REF: CAL0115846 heterozygous diploid, classical genetics repressible SC5314 resistance to chemicals: decreased terbinafine C. albicans orf19.406 ORF ERG1 CAL0005541 PMID: 16246085|CGD_REF: CAL0114864 heterozygous diploid, classical genetics repressible Not recorded resistance to chemicals: decreased fluconazole C. albicans orf19.406 ORF ERG1 CAL0005541 PMID: 21135205|CGD_REF: CAL0139967 heterozygous diploid, large-scale survey (large-scale identification of genes essential for virulence in mouse) repressible CAI-4 virulence: absent mouse intravenous infection C. albicans orf19.4060 ORF ARO4 CAL0004867 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.4062 ORF TRY2 CAL0004873 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.4062 ORF TRY2 CAL0004873 PMID: 22359502|CGD_REF: CAL0000144048 homozygous diploid, classical genetics null BWP17 viable independent insertion mutant isolates tested C. albicans orf19.4062 ORF TRY2 CAL0004873 PMID: 22359502|CGD_REF: CAL0000144048 homozygous diploid, classical genetics null BWP17 adhesion: decreased independent insertion mutant isolates tested C. albicans orf19.4063 ORF GPT1 CAL0004875 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.4064 ORF GPI7 CAL0004876 PMID: 12101300|CGD_REF: CAL0081357 homozygous diploid, classical genetics null Not recorded resistance to enzymatic treatment: decreased cell wall lytic enzymes C. albicans orf19.4064 ORF GPI7 CAL0004876 PMID: 11994163|CGD_REF: CAL0081358 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased Calcofluor White C. albicans orf19.4064 ORF GPI7 CAL0004876 PMID: 12101300|CGD_REF: CAL0081357 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased sodium dodecyl sulfate C. albicans orf19.4064 ORF GPI7 CAL0004876 PMID: 11994163|CGD_REF: CAL0081358 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.4064 ORF GPI7 CAL0004876 PMID: 12101300|CGD_REF: CAL0081357 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.4064 ORF GPI7 CAL0004876 PMID: 11994163|CGD_REF: CAL0081358 homozygous diploid, classical genetics null Not recorded hyphal growth: absent solid medium C. albicans orf19.4064 ORF GPI7 CAL0004876 PMID: 12101300|CGD_REF: CAL0081357 homozygous diploid, classical genetics null Not recorded cell wall morphology: abnormal association of GPI-linked proteins and cell wall mannoproteins is decreased C. albicans orf19.4064 ORF GPI7 CAL0004876 PMID: 12101300|CGD_REF: CAL0081357 homozygous diploid, classical genetics null Not recorded chitin deposition: abnormal cell wall exhibits increased chitin content C. albicans orf19.4064 ORF GPI7 CAL0004876 PMID: 11994163|CGD_REF: CAL0081358 homozygous diploid, classical genetics null Not recorded osmotic stress resistance: abnormal C. albicans orf19.4064 ORF GPI7 CAL0004876 PMID: 12101300|CGD_REF: CAL0081357 homozygous diploid, classical genetics null Not recorded chemical compound accumulation: decreased mannan decreased cell wall mannan C. albicans orf19.4064 ORF GPI7 CAL0004876 PMID: 18403244|CGD_REF: CAL0118959 homozygous diploid, classical genetics null SC5314 induction of host response: abnormal murine proinflammatory response is enhanced C. albicans orf19.4064 ORF GPI7 CAL0004876 PMID: 11994163|CGD_REF: CAL0081358 homozygous diploid, classical genetics null CAI-4 resistance to killing by host cells: decreased in vitro model of infection (J774 macrophages) C. albicans orf19.4064 ORF GPI7 CAL0004876 PMID: 11994163|CGD_REF: CAL0081358 homozygous diploid, classical genetics null Not recorded virulence: decreased mouse intravenous infection C. albicans orf19.4064 ORF GPI7 CAL0004876 PMID: 18403244|CGD_REF: CAL0118959 homozygous diploid, classical genetics null Not recorded virulence: decreased mouse intravenous infection C. albicans orf19.4066 ORF CAL0004879 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.4066 ORF CAL0004879 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.4066 ORF CAL0004879 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.4066 ORF CAL0004879 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.4067 ORF FGR18 CAL0004880 PMID: 12773383|CGD_REF: CAL0087974 heterozygous diploid, classical genetics (haploinsufficient phenotype assay) unspecified CAI-4 filamentous growth: decreased solid Spider medium transposon insertion proximal to, but not within, the ORF C. albicans orf19.407 ORF GCD6 CAL0005543 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.407 ORF GCD6 CAL0005543 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 invasive growth: decreased solid SLAD media C. albicans orf19.407 ORF GCD6 CAL0005543 PMID: 21135205|CGD_REF: CAL0139967 heterozygous diploid, large-scale survey (large-scale identification of genes essential for virulence in mouse) repressible CAI-4 virulence: absent mouse intravenous infection C. albicans orf19.4072 ORF IFF6 CAL0004905 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.4072 ORF IFF6 CAL0004905 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.4072 ORF IFF6 CAL0004905 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.4072 ORF IFF6 CAL0004905 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.4076 ORF MET10 CAL0004909 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.4077 ORF MIT1 CAL0004910 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.4077 ORF MIT1 CAL0004910 PMID: 15347680|CGD_REF: CAL0082133 homozygous diploid, classical genetics null CAI-4 resistance to killing by host cells: decreased decreased survival in the presence of macrophages in vitro model of infection (J774 macrophages) C. albicans orf19.4077 ORF MIT1 CAL0004910 PMID: 15347680|CGD_REF: CAL0082133 homozygous diploid, classical genetics null CAI-4 viable wild-type growth rate C. albicans orf19.4077 ORF MIT1 CAL0004910 PMID: 15347680|CGD_REF: CAL0082133 homozygous diploid, classical genetics null CAI-4 virulence: decreased C. albicans orf19.4077 ORF MIT1 CAL0004910 PMID: 15347680|CGD_REF: CAL0082133 homozygous diploid, classical genetics null CAI-4 resistance to chemicals: decreased calcium(2+)|sodium dodecyl sulfate C. albicans orf19.4078 ORF CAL0004911 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.4082 ORF DDR48 CAL0004933 PMID: 18509269|CGD_REF: CAL0119014 heterozygous diploid, classical genetics null Not recorded hyphal growth: decreased inducing conditions C. albicans orf19.4082 ORF DDR48 CAL0004933 PMID: 18509269|CGD_REF: CAL0119014 heterozygous diploid, classical genetics null Not recorded oxidative stress resistance: decreased hydrogen peroxide C. albicans orf19.4082 ORF DDR48 CAL0004933 PMID: 18509269|CGD_REF: CAL0119014 homozygous diploid, classical genetics null Not recorded inviable homozygous null mutant strain could not be recovered, suggesting that the gene is essential under the selection conditions C. albicans orf19.4082 ORF DDR48 CAL0004933 PMID: 18509269|CGD_REF: CAL0119014 heterozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased triazoles C. albicans orf19.4082 ORF DDR48 CAL0004933 PMID: 22523369|CGD_REF: CAL0000157173 homozygous diploid, classical genetics null BWP17 resistance to chemicals: decreased 4-nitroquinoline N-oxide C. albicans orf19.4082 ORF DDR48 CAL0004933 PMID: 22523369|CGD_REF: CAL0000157173 homozygous diploid, classical genetics null BWP17 viable C. albicans orf19.4082 ORF DDR48 CAL0004933 PMID: 22523369|CGD_REF: CAL0000157173 homozygous diploid, classical genetics null BWP17 resistance to chemicals: increased rapamycin at 37 deg C. albicans orf19.4082 ORF DDR48 CAL0004933 PMID: 22523369|CGD_REF: CAL0000157173 homozygous diploid, classical genetics null BWP17 resistance to chemicals: increased amphotericin B at 37 deg C. albicans orf19.4082 ORF DDR48 CAL0004933 PMID: 22523369|CGD_REF: CAL0000157173 homozygous diploid, classical genetics null BWP17 resistance to chemicals: increased sodium dodecyl sulfate at 37 deg C. albicans orf19.4082 ORF DDR48 CAL0004933 PMID: 18509269|CGD_REF: CAL0119014 heterozygous diploid, classical genetics null Not recorded virulence: normal C. albicans orf19.4084 ORF KIS1 CAL0004936 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: decreased growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.4084 ORF KIS1 CAL0004936 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: abnormal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.4084 ORF KIS1 CAL0004936 PMID: 23856128|CGD_REF: CAL0000172540 homozygous diploid, classical genetics null BWP17 resistance to chemicals: decreased propolis C. albicans orf19.4084 ORF KIS1 CAL0004936 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.4084 ORF KIS1 CAL0004936 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.4088 ORF GLO2 CAL0004940 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.4089 ORF SGT1 CAL0004941 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.4089 ORF SGT1 CAL0004941 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, competitive growth (haploinsufficient phenotype assay, barcode deletion set) null SC5314 resistance to chemicals: decreased radicicol C. albicans orf19.4089 ORF SGT1 CAL0004941 PMID: 19115836|CGD_REF: CAL0122036 heterozygous diploid, competitive growth (haploinsufficient phenotype assay, barcode deletion set) null SC5314 resistance to chemicals: decreased radicicol C. albicans orf19.4089 ORF SGT1 CAL0004941 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.4089 ORF SGT1 CAL0004941 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.4089 ORF SGT1 CAL0004941 PMID: 22970302|CGD_REF: CAL0000157840 heterozygous diploid, classical genetics repressible tetO-SGT1/sgt1 SN95 invasive growth: increased repressive conditions, doxycycline or tetracycline C. albicans orf19.4089 ORF SGT1 CAL0004941 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.4089 ORF SGT1 CAL0004941 PMID: 22970302|CGD_REF: CAL0000157840 heterozygous diploid, classical genetics repressible tetO-SGT1/sgt1 SN95 filamentous growth: increased repressive conditions, doxycycline or tetracycline C. albicans orf19.4089 ORF SGT1 CAL0004941 PMID: 22970302|CGD_REF: CAL0000157840 heterozygous diploid, classical genetics repressible tetO-SGT1/sgt1 SN95 colony shape: abnormal repressive conditions, doxycycline or tetracycline wrinkly colonies C. albicans orf19.4089 ORF SGT1 CAL0004941 PMID: 22970302|CGD_REF: CAL0000157840 heterozygous diploid, classical genetics repressible tetO-SGT1/sgt1 SN95 virulence: decreased repressive conditions, doxycycline or tetracycline reduced kidney fungal burden mouse intravenous infection C. albicans orf19.4089 ORF SGT1 CAL0004941 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.4093 ORF PES1 CAL0004971 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, competitive growth (haploinsufficient phenotype assay, barcode deletion set) null SC5314 resistance to chemicals: decreased 5-fluorouracil C. albicans orf19.4093 ORF PES1 CAL0004971 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, competitive growth (haploinsufficient phenotype assay, barcode deletion set) null SC5314 resistance to chemicals: decreased tubercidin C. albicans orf19.4093 ORF PES1 CAL0004971 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, competitive growth (haploinsufficient phenotype assay, barcode deletion set) null SC5314 resistance to chemicals: decreased flucytosine C. albicans orf19.4093 ORF PES1 CAL0004971 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.4093 ORF PES1 CAL0004971 PMID: 19075239|CGD_REF: CAL0122005 heterozygous diploid, classical genetics repressible nop7-W416R/nop7 null Not recorded heat sensitivity: increased 37 deg C, rich medium C. albicans orf19.4093 ORF PES1 CAL0004971 PMID: 19075239|CGD_REF: CAL0122005 heterozygous diploid, classical genetics repressible SC5314 filamentous growth: abnormal abolished lateral yeast growth (filament-to-yeast switching) C. albicans orf19.4093 ORF PES1 CAL0004971 PMID: 19075239|CGD_REF: CAL0122005 heterozygous diploid, classical genetics overexpression SC5314 filamentous growth: decreased decreased filamentous growth and increased lateral yeast growth (filament-to-yeast switching) C. albicans orf19.4093 ORF PES1 CAL0004971 PMID: 23104566|CGD_REF: CAL0000158097 homozygous diploid, classical genetics repressible tetO-PES1/pes1 SC5314 virulence: decreased only hyphae seen in mouse kidneys mouse intravenous infection C. albicans orf19.4093 ORF PES1 CAL0004971 PMID: 19075239|CGD_REF: CAL0122005 heterozygous diploid, classical genetics repressible Not recorded virulence: absent Galleria mellonella (Greater Wax Moth) larvae insect infection C. albicans orf19.4093 ORF PES1 CAL0004971 PMID: 20360962|CGD_REF: CAL0125164 heterozygous diploid, classical genetics overexpression Other C. albicans biofilm formation: abnormal increased dispersal of yeast-form cells from the biofilm C. albicans orf19.410.3 ORF RIB4 CAF0006895 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.4101 ORF CAL0005549 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 invasive growth: decreased solid SLAD media C. albicans orf19.4102 ORF RPN10 CAL0005551 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.4104 ORF CAL0005554 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.4104 ORF CAL0005554 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.4104 ORF CAL0005554 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.4104 ORF CAL0005554 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.4106 ORF CAL0005558 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.4109 ORF PMT4 CAL0005560 PMID: 15659169|CGD_REF: CAL0082300 homozygous diploid, classical genetics null Not recorded flocculation: increased C. albicans orf19.4109 ORF PMT4 CAL0005560 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.4109 ORF PMT4 CAL0005560 PMID: 15659169|CGD_REF: CAL0082300 heterozygous diploid, classical genetics null Not recorded viable C. albicans orf19.4109 ORF PMT4 CAL0005560 PMID: 15659169|CGD_REF: CAL0082300 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.4109 ORF PMT4 CAL0005560 PMID: 15659169|CGD_REF: CAL0082300 homozygous diploid, classical genetics null CAI-4 hyphal growth: absent Lee's or Spider media C. albicans orf19.4109 ORF PMT4 CAL0005560 PMID: 15659169|CGD_REF: CAL0082300 homozygous diploid, classical genetics null CAI-4 hyphal growth: normal oxygen-limited conditions C. albicans orf19.4109 ORF PMT4 CAL0005560 PMID: 15659169|CGD_REF: CAL0082300 homozygous diploid, classical genetics null CAI-4 hyphal growth: normal serum-containing medium C. albicans orf19.4109 ORF PMT4 CAL0005560 PMID: 17005840|CGD_REF: CAL0116746 homozygous diploid, classical genetics null Not recorded biofilm formation: decreased moderate reduction C. albicans orf19.4109 ORF PMT4 CAL0005560 PMID: 15659169|CGD_REF: CAL0082300 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased Hygromycin B C. albicans orf19.4109 ORF PMT4 CAL0005560 PMID: 15659169|CGD_REF: CAL0082300 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased geneticin C. albicans orf19.4109 ORF PMT4 CAL0005560 PMID: 21375589|CGD_REF: CAL0141772 homozygous diploid, classical genetics null CAF2-1 resistance to chemicals: decreased tunicamycin C. albicans orf19.4109 ORF PMT4 CAL0005560 PMID: 17005840|CGD_REF: CAL0116746 homozygous diploid, classical genetics null CAF2-1 biofilm formation: decreased moderate reduction C. albicans orf19.4109 ORF PMT4 CAL0005560 PMID: 15659169|CGD_REF: CAL0082300 homozygous diploid, classical genetics null Not recorded virulence: decreased mouse intravenous infection C. albicans orf19.411 ORF CAL0005571 PMID: 14663094|CGD_REF: CAL0080633 homozygous diploid, systematic mutation set (homozygous insertion mutants generated with URA3-ARG4-URA3 (UAU1) cassette) null BWP17 viable C. albicans orf19.4112 ORF CAL0005587 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.4114 ORF FAA2-1 CAL0005590 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.4116 ORF CAL0005594 PMID: 14663094|CGD_REF: CAL0080633 homozygous diploid, systematic mutation set (homozygous insertion mutants generated with URA3-ARG4-URA3 (UAU1) cassette) null BWP17 viable C. albicans orf19.4117 ORF CAL0005595 PMID: 14663094|CGD_REF: CAL0080633 homozygous diploid, systematic mutation set (homozygous insertion mutants generated with URA3-ARG4-URA3 (UAU1) cassette) null BWP17 viable C. albicans orf19.4118 ORF CNT CAL0005596 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, competitive growth (haploinsufficient phenotype assay, barcode deletion set) null SC5314 resistance to chemicals: increased tubercidin C. albicans orf19.4118 ORF CNT CAL0005596 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, classical genetics repressible SC5314 resistance to chemicals: increased tubercidin C. albicans orf19.4118 ORF CNT CAL0005596 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.4118 ORF CNT CAL0005596 PMID: 19623926|CGD_REF: CAL0124054 heterozygous diploid, competitive growth (haploinsufficient phenotype assay, barcode deletion set) null SC5314 resistance to chemicals: increased cordycepin C. albicans orf19.4118 ORF CNT CAL0005596 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.4118 ORF CNT CAL0005596 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.4118 ORF CNT CAL0005596 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient YPD medium C. albicans orf19.4118 ORF CNT CAL0005596 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.4118 ORF CNT CAL0005596 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.4119 ORF SPO72 CAL0005597 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.412 ORF SSH1 CAL0005572 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.4120 ORF LAS1 CAL0005623 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, competitive growth (haploinsufficient phenotype assay, barcode deletion set) null SC5314 resistance to chemicals: decreased 5-fluorouracil C. albicans orf19.4120 ORF LAS1 CAL0005623 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, competitive growth (haploinsufficient phenotype assay, barcode deletion set) null SC5314 resistance to chemicals: decreased flucytosine C. albicans orf19.4120 ORF LAS1 CAL0005623 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.4120 ORF LAS1 CAL0005623 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 invasive growth: decreased solid SLAD media C. albicans orf19.4125 ORF PZF1 CAL0005633 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.4125 ORF PZF1 CAL0005633 PMID: 15964282|CGD_REF: CAL0114274 homozygous diploid, systematic mutation set (split-marker transposon insertion strategy to disrupt both alleles) null BWP17 viable C. albicans orf19.4125 ORF PZF1 CAL0005633 PMID: 19463063|CGD_REF: CAL0123630 homozygous diploid, systematic mutation set (split-marker transposon insertion strategy to disrupt both alleles) null BWP17 viable C. albicans orf19.4125 ORF PZF1 CAL0005633 PMID: 15964282|CGD_REF: CAL0114274 homozygous diploid, systematic mutation set (split-marker transposon insertion strategy to disrupt both alleles) null BWP17 biofilm formation: normal C. albicans orf19.4125 ORF PZF1 CAL0005633 PMID: 19463063|CGD_REF: CAL0123630 homozygous diploid, systematic mutation set (split-marker transposon insertion strategy to disrupt both alleles) null BWP17 virulence: normal Toll mutant D. melanogaster invasive infection insect infection C. albicans orf19.4125 ORF PZF1 CAL0005633 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 invasive growth: decreased solid SLAD media C. albicans orf19.4133 ORF CAL0005669 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.4135 ORF PRC2 CAL0005673 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.4135 ORF PRC2 CAL0005673 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.4135 ORF PRC2 CAL0005673 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.4135 ORF PRC2 CAL0005673 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.4136 ORF YBL053 CAL0005675 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.4136 ORF YBL053 CAL0005675 PMID: 14663094|CGD_REF: CAL0080633 homozygous diploid, systematic mutation set (homozygous insertion mutants generated with URA3-ARG4-URA3 (UAU1) cassette) null BWP17 viable C. albicans orf19.4136 ORF YBL053 CAL0005675 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.4136 ORF YBL053 CAL0005675 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: decreased rate liquid synthetic complete medium C. albicans orf19.4136 ORF YBL053 CAL0005675 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.4142 ORF CAL0005710 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.4144 ORF CAL0005714 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.4146 ORF SMD3 CAL0005718 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.4147 ORF GLR1 CAL0005719 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.4149.1 ORF CAF0007002 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.4150 ORF CAL0005739 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.4151 ORF SPO1 CAL0005743 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.4151 ORF SPO1 CAL0005743 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 invasive growth: decreased solid SLAD media C. albicans orf19.4152 ORF CEF3 CAL0005746 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.4152 ORF CEF3 CAL0005746 PMID: 14507372|CGD_REF: CAL0088818 heterozygous diploid, large-scale survey (large-scale identification of essential genes by gene replacement and conditional expression (GRACE) method) repressible CAI-4 inviable one allele is deleted and the other is placed under repressible Tet promoter C. albicans orf19.4152 ORF CEF3 CAL0005746 PMID: 21135205|CGD_REF: CAL0139967 heterozygous diploid, large-scale survey (large-scale identification of genes essential for virulence in mouse) repressible CAI-4 virulence: absent mouse intravenous infection C. albicans orf19.4157 ORF SPS20 CAL0005754 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.4157 ORF SPS20 CAL0005754 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.4157 ORF SPS20 CAL0005754 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.4157 ORF SPS20 CAL0005754 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.4157 ORF SPS20 CAL0005754 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.4160 ORF CAL0005771 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.4161 ORF CAL0005775 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.4162 ORF MLH1 CAL0005779 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.4166 ORF ZCF21 CAL0005785 PMID: 20041210|CGD_REF: CAL0124764 homozygous diploid, systematic mutation set null SN152 resistance to chemicals: decreased caffeine strongly sensitive C. albicans orf19.4166 ORF ZCF21 CAL0005785 PMID: 23526879|CGD_REF: CAL0000158852 homozygous diploid, classical genetics null SN152 virulence: decreased mouse intravenous infection C. albicans orf19.4166 ORF ZCF21 CAL0005785 PMID: 23526879|CGD_REF: CAL0000158852 homozygous diploid, classical genetics null SN152 virulence: decreased weak defect in GI tract colonization mouse gastrointestinal tract infection C. albicans orf19.4166 ORF ZCF21 CAL0005785 PMID: 23526879|CGD_REF: CAL0000158852 homozygous diploid, classical genetics null SN152 viable C. albicans orf19.4168 ORF CAL0005787 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.4169 ORF CAL0005788 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient YPD medium C. albicans orf19.4169 ORF CAL0005788 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient YNB medium C. albicans orf19.417 ORF MTM1 CAL0005580 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.417 ORF MTM1 CAL0005580 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 invasive growth: decreased solid SLAD media C. albicans orf19.4171 ORF CAL0005809 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.4172 ORF CAL0005813 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.4174 ORF CAL0005817 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.4174 ORF CAL0005817 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.4174 ORF CAL0005817 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.4174 ORF CAL0005817 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.4174 ORF CAL0005817 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.4175 ORF TOK1 CAL0005819 PMID: 12761106|CGD_REF: CAL0087951 homozygous diploid, classical genetics null Not recorded toxin resistance: decreased human salivary histatin 5 C. albicans orf19.4175 ORF TOK1 CAL0005819 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.4175 ORF TOK1 CAL0005819 PMID: 12761106|CGD_REF: CAL0087951 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.4175 ORF TOK1 CAL0005819 PMID: 19175416|CGD_REF: CAL0122293 homozygous diploid, classical genetics null Not recorded small molecule transport: decreased potassium(1+) decreased K+ efflux C. albicans orf19.4175 ORF TOK1 CAL0005819 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.4175 ORF TOK1 CAL0005819 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.4175 ORF TOK1 CAL0005819 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.4175 ORF TOK1 CAL0005819 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.4177 ORF HIS5 CAL0005821 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.418 ORF KOG1 CAL0005582 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.418 ORF KOG1 CAL0005582 PMID: 19115836|CGD_REF: CAL0122036 heterozygous diploid, competitive growth (haploinsufficient phenotype assay, barcode deletion set) null SC5314 resistance to chemicals: decreased rapamycin C. albicans orf19.418 ORF KOG1 CAL0005582 PMID: 12524333|CGD_REF: CAL0080691 homozygous diploid, systematic mutation set (homozygous insertion mutants generated with URA3-ARG4-URA3 (UAU1) cassette) null BWP17 inviable homozygous null mutant strain could not be recovered, suggesting that the gene is essential under the selection conditions C. albicans orf19.4182 ORF CAL0005850 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.4182 ORF CAL0005850 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: decreased growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.4182 ORF CAL0005850 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: abnormal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.4182 ORF CAL0005850 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, classical genetics null SN152 germ tube formation: decreased serum-containing medium C. albicans orf19.4182 ORF CAL0005850 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: decreased rate liquid synthetic complete medium C. albicans orf19.4182 ORF CAL0005850 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.4183 ORF MUC1 CAL0005852 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.4183 ORF MUC1 CAL0005852 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.4183 ORF MUC1 CAL0005852 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.4183 ORF MUC1 CAL0005852 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.4183 ORF MUC1 CAL0005852 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.4185 ORF CAL0005856 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.4185 ORF CAL0005856 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.4185 ORF CAL0005856 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.4185 ORF CAL0005856 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.4186 ORF PCT1 CAL0005857 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.4187 ORF CAL0005858 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.4187 ORF CAL0005858 PMID: 21135205|CGD_REF: CAL0139967 heterozygous diploid, large-scale survey (large-scale identification of genes essential for virulence in mouse) repressible CAI-4 virulence: absent mouse intravenous infection C. albicans orf19.4188 ORF NMD5 CAL0005859 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.4188 ORF NMD5 CAL0005859 PMID: 14663094|CGD_REF: CAL0080633 homozygous diploid, systematic mutation set (homozygous insertion mutants generated with URA3-ARG4-URA3 (UAU1) cassette) null BWP17 viable C. albicans orf19.4188 ORF NMD5 CAL0005859 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: decreased growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.4188 ORF NMD5 CAL0005859 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.4188 ORF NMD5 CAL0005859 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.4188 ORF NMD5 CAL0005859 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.4189 ORF CAL0005860 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.4189 ORF CAL0005860 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.4189 ORF CAL0005860 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.4189 ORF CAL0005860 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.419 ORF CAL0005585 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.419 ORF CAL0005585 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.419 ORF CAL0005585 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.419 ORF CAL0005585 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.4190 ORF PAM18 CAL0005879 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.4191 ORF RLP24 CAL0005882 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, competitive growth (haploinsufficient phenotype assay, barcode deletion set) null SC5314 resistance to chemicals: decreased 5-fluorouracil C. albicans orf19.4191 ORF RLP24 CAL0005882 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, competitive growth (haploinsufficient phenotype assay, barcode deletion set) null SC5314 resistance to chemicals: decreased tubercidin C. albicans orf19.4191 ORF RLP24 CAL0005882 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, competitive growth (haploinsufficient phenotype assay, barcode deletion set) null SC5314 resistance to chemicals: decreased flucytosine C. albicans orf19.4191 ORF RLP24 CAL0005882 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.4191 ORF RLP24 CAL0005882 PMID: 16607011|CGD_REF: CAL0115846 heterozygous diploid, classical genetics null SC5314 viable C. albicans orf19.4191 ORF RLP24 CAL0005882 PMID: 16607011|CGD_REF: CAL0115846 homozygous diploid, classical genetics null SC5314 inviable homozygous null mutant strain could not be recovered, suggesting that the gene is essential under the selection conditions C. albicans orf19.4191 ORF RLP24 CAL0005882 PMID: 16607011|CGD_REF: CAL0115846 heterozygous diploid, classical genetics repressible SC5314 inviable C. albicans orf19.4192 ORF CDC14 CAL0005886 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.4192 ORF CDC14 CAL0005886 PMID: 16507592|CGD_REF: CAL0115695 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.4192 ORF CDC14 CAL0005886 PMID: 16507592|CGD_REF: CAL0115695 homozygous diploid, classical genetics null Not recorded cytokinesis: absent C. albicans orf19.4192 ORF CDC14 CAL0005886 PMID: 16507592|CGD_REF: CAL0115695 homozygous diploid, classical genetics null CAI-4 filamentous growth: abnormal C. albicans orf19.4193 ORF CAL0005888 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.4193 ORF CAL0005888 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.4193 ORF CAL0005888 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.4193 ORF CAL0005888 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient SC medium C. albicans orf19.4193 ORF CAL0005888 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.4194 ORF CAL0005890 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.4195 ORF CAL0005892 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.4195 ORF CAL0005892 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.4195 ORF CAL0005892 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.4195 ORF CAL0005892 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.4195.1 ORF FCA1 CAL0006519 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.4195.1 ORF FCA1 CAL0006519 PMID: 15504867|CGD_REF: CAL0082142 unknown ploidy, classical genetics unspecified Other C. albicans resistance to chemicals: increased flucytosine mutations are associated with resistance to flucytosine (5-FC) in clinical isolates C. albicans orf19.4197 ORF YHM2 CAL0005894 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.4199 ORF SLY41 CAL0005895 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.4203 ORF CAL0000057 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.4204 ORF CAL0000059 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient YPD medium C. albicans orf19.4204 ORF CAL0000059 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 invasive growth: decreased solid SLAD media C. albicans orf19.4205.1 ORF CAF0007005 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.4208 ORF RAD52 CAL0000064 PMID: 15306020|CGD_REF: CAL0082076 homozygous diploid, classical genetics null Not recorded UV resistance: decreased C. albicans orf19.4208 ORF RAD52 CAL0000064 PMID: 16468988|CGD_REF: CAL0115570 heterozygous diploid, classical genetics repressible Not recorded UV resistance: decreased C. albicans orf19.4208 ORF RAD52 CAL0000064 PMID: 17965250|CGD_REF: CAL0118884 homozygous diploid, classical genetics null Not recorded UV resistance: decreased C. albicans orf19.4208 ORF RAD52 CAL0000064 PMID: 16468988|CGD_REF: CAL0115570 homozygous diploid, classical genetics null Not recorded vegetative growth: decreased rate YPD medium generation time of 140 min C. albicans orf19.4208 ORF RAD52 CAL0000064 PMID: 15306020|CGD_REF: CAL0082076 homozygous diploid, classical genetics null Not recorded vegetative growth: decreased rate C. albicans orf19.4208 ORF RAD52 CAL0000064 PMID: 17965250|CGD_REF: CAL0118884 homozygous diploid, classical genetics null Not recorded vegetative growth: decreased rate C. albicans orf19.4208 ORF RAD52 CAL0000064 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.4208 ORF RAD52 CAL0000064 PMID: 15306020|CGD_REF: CAL0082076 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.4208 ORF RAD52 CAL0000064 PMID: 17965250|CGD_REF: CAL0118884 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.4208 ORF RAD52 CAL0000064 PMID: 18026727|CGD_REF: CAL0118863 heterozygous diploid, classical genetics null Not recorded viable C. albicans orf19.4208 ORF RAD52 CAL0000064 PMID: 18026727|CGD_REF: CAL0118863 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.4208 ORF RAD52 CAL0000064 PMID: 18026727|CGD_REF: CAL0118863 heterozygous diploid, classical genetics overexpression Not recorded viable C. albicans orf19.4208 ORF RAD52 CAL0000064 PMID: 17965250|CGD_REF: CAL0118884 homozygous diploid, classical genetics null Not recorded oxidative stress resistance: decreased hydrogen peroxide C. albicans orf19.4208 ORF RAD52 CAL0000064 PMID: 15306020|CGD_REF: CAL0082076 homozygous diploid, classical genetics null Not recorded mitotic recombination: decreased decreased homologous recombination C. albicans orf19.4208 ORF RAD52 CAL0000064 PMID: 18026727|CGD_REF: CAL0118863 homozygous diploid, classical genetics null Not recorded mutation frequency: decreased decreased UV-induced loss of heterozygosity (LOH) C. albicans orf19.4208 ORF RAD52 CAL0000064 PMID: 18026727|CGD_REF: CAL0118863 heterozygous diploid, classical genetics null Not recorded mutation frequency: decreased decreased UV-induced loss of heterozygosity (LOH); phenotype is intermediate between that of wild type and the homozygous null mutant C. albicans orf19.4208 ORF RAD52 CAL0000064 PMID: 18026727|CGD_REF: CAL0118863 heterozygous diploid, classical genetics overexpression Not recorded mutation frequency: increased increased UV-induced loss of heterozygosity (LOH) C. albicans orf19.4208 ORF RAD52 CAL0000064 PMID: 17965250|CGD_REF: CAL0118884 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased ethyl methanesulfonate C. albicans orf19.4208 ORF RAD52 CAL0000064 PMID: 15306020|CGD_REF: CAL0082076 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased methyl methanesulfonate C. albicans orf19.4208 ORF RAD52 CAL0000064 PMID: 16468988|CGD_REF: CAL0115570 heterozygous diploid, classical genetics repressible Not recorded resistance to chemicals: decreased methyl methanesulfonate C. albicans orf19.4208 ORF RAD52 CAL0000064 PMID: 17965250|CGD_REF: CAL0118884 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased methyl methanesulfonate C. albicans orf19.4208 ORF RAD52 CAL0000064 PMID: 15306020|CGD_REF: CAL0082076 heterozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased methyl methanesulfonate C. albicans orf19.4208 ORF RAD52 CAL0000064 PMID: 17965250|CGD_REF: CAL0118884 homozygous diploid, classical genetics null Not recorded oxidative stress resistance: decreased tert-butyl hydroperoxide C. albicans orf19.4208 ORF RAD52 CAL0000064 PMID: 19458191|CGD_REF: CAL0123591 homozygous diploid, classical genetics null Not recorded phenotypic switching: increased white-to-opaque switching C. albicans orf19.4208 ORF RAD52 CAL0000064 PMID: 16468988|CGD_REF: CAL0115570 homozygous diploid, classical genetics null CAI-4 filamentous growth: abnormal mixture of elongated pseudohyphae and true hyphae C. albicans orf19.4208 ORF RAD52 CAL0000064 PMID: 17965250|CGD_REF: CAL0118884 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased camptothecin C. albicans orf19.4208 ORF RAD52 CAL0000064 PMID: 17965250|CGD_REF: CAL0118884 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased fluconazole C. albicans orf19.4208 ORF RAD52 CAL0000064 PMID: 21272099|CGD_REF: CAL0141414 homozygous diploid, classical genetics null rad52::hisG/rad52::hisG-URA3-hisG CAI-4 chromosome/plasmid maintenance: abnormal increased loss of heterozygosity at HIS4 locus C. albicans orf19.4208 ORF RAD52 CAL0000064 PMID: 16299301|CGD_REF: CAL0114215 homozygous diploid, classical genetics null Not recorded virulence: absent low inoculum exhibits decreased kidney colonization and decreased virulence at high inoculum mouse intravenous infection C. albicans orf19.4208 ORF RAD52 CAL0000064 PMID: 16299301|CGD_REF: CAL0114215 heterozygous diploid, classical genetics null Not recorded virulence: normal mouse intravenous infection C. albicans orf19.4208 ORF RAD52 CAL0000064 PMID: 20206282|CGD_REF: CAL0125104 homozygous diploid, classical genetics null rad52::hisG/rad52::hisG-URA3-hisG CAI-4 UV resistance: decreased C. albicans orf19.4208 ORF RAD52 CAL0000064 PMID: 20206282|CGD_REF: CAL0125104 homozygous diploid, classical genetics null rad52::hisG/rad52::hisG-URA3-hisG CAI-4 resistance to chemicals: decreased methyl methanesulfonate C. albicans orf19.4208 ORF RAD52 CAL0000064 PMID: 20206282|CGD_REF: CAL0125104 homozygous diploid, classical genetics null rad52::hisG/rad52::hisG-URA3-hisG CAI-4 resistance to chemicals: decreased bleomycin C. albicans orf19.4208 ORF RAD52 CAL0000064 PMID: 20206282|CGD_REF: CAL0125104 homozygous diploid, classical genetics null rad52::hisG/rad52::hisG-URA3-hisG CAI-4 resistance to chemicals: decreased camptothecin C. albicans orf19.4208 ORF RAD52 CAL0000064 PMID: 20206282|CGD_REF: CAL0125104 homozygous diploid, classical genetics null rad52::hisG/rad52::hisG-URA3-hisG CAI-4 oxidative stress resistance: decreased hydrogen peroxide similar slight sensitivity seen with menadione or tBOOH C. albicans orf19.4209 ORF CAL0000065 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 invasive growth: decreased solid SLAD media C. albicans orf19.4210 ORF CAL0000088 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.4211 ORF CAL0000091 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.4211 ORF CAL0000091 PMID: 17470538|CGD_REF: CAL0118025 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.4211 ORF CAL0000091 PMID: 10517594|CGD_REF: CAL0081291 homozygous diploid, classical genetics null fet3::hisG/fet3::hisG-URA3::hisG CAI-4 utilization of iron source: decreased iron trichloride C. albicans orf19.4211 ORF CAL0000091 PMID: 10517594|CGD_REF: CAL0081291 homozygous diploid, classical genetics null fet3::hisG/fet3::hisG-URA3::hisG CAI-4 adhesion: decreased adhesion to mouse L929 fibroblasts C. albicans orf19.4211 ORF CAL0000091 PMID: 10517594|CGD_REF: CAL0081291 homozygous diploid, classical genetics null fet3::hisG/fet3::hisG-URA3::hisG CAI-4 viable C. albicans orf19.4211 ORF CAL0000091 PMID: 17470538|CGD_REF: CAL0118025 homozygous diploid, classical genetics null Not recorded chemical compound accumulation: decreased prostaglandin E2 C. albicans orf19.4211 ORF CAL0000091 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, competitive growth (haploinsufficient phenotype assay, barcode deletion set) null SC5314 resistance to chemicals: decreased ergosterol analogs (ECC69 and/or ECC1384) C. albicans orf19.4211 ORF CAL0000091 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.4211 ORF CAL0000091 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.4211 ORF CAL0000091 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.4211 ORF CAL0000091 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.4212 ORF FET99 CAL0000094 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.4212 ORF FET99 CAL0000094 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.4212 ORF FET99 CAL0000094 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.4212 ORF FET99 CAL0000094 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.4213 ORF CAL0000096 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.4213 ORF CAL0000096 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 invasive growth: decreased solid SLAD media C. albicans orf19.4214 ORF CAL0000098 PMID: 14663094|CGD_REF: CAL0080633 homozygous diploid, systematic mutation set (homozygous insertion mutants generated with URA3-ARG4-URA3 (UAU1) cassette) null BWP17 viable C. albicans orf19.4215 ORF FET34 CAL0000100 PMID: 23579686|CGD_REF: CAL0000158899 homozygous diploid, classical genetics null fet34::ARG4/fet34::URA3-dpl200 BWP17 viable C. albicans orf19.4215 ORF FET34 CAL0000100 PMID: 23579686|CGD_REF: CAL0000158899 homozygous diploid, classical genetics null fet34::ARG4/fet34::URA3-dpl200 BWP17 chemical compound accumulation: decreased cellular iron iron limiting conditions no obvious growth defect in iron-limited medium C. albicans orf19.4215 ORF FET34 CAL0000100 PMID: 23579686|CGD_REF: CAL0000158899 homozygous diploid, classical genetics null fet34::ARG4/fet34::URA3-dpl200 BWP17 filamentous growth: decreased 30 and 37 degrees C Spider medium C. albicans orf19.4215 ORF FET34 CAL0000100 PMID: 23579686|CGD_REF: CAL0000158899 homozygous diploid, classical genetics null fet34::ARG4/fet34::URA3-dpl200 BWP17 filamentous growth: decreased N-acetylglucosamine, 30 and 37 degrees C defective in GlcNAc at 30 degrees C, not 37 degrees C C. albicans orf19.4215 ORF FET34 CAL0000100 PMID: 23579686|CGD_REF: CAL0000158899 homozygous diploid, classical genetics null fet34::ARG4/fet34::URA3-dpl200 BWP17 filamentous growth: decreased RPMI1640 solid medium defective in filamentous growth slightly at 30 degrees C, more so at 37 degrees C C. albicans orf19.4215 ORF FET34 CAL0000100 PMID: 23579686|CGD_REF: CAL0000158899 homozygous diploid, classical genetics null fet34::ARG4/fet34::URA3-dpl200 BWP17 virulence: decreased mouse intravenous infection C. albicans orf19.4219 ORF RIX7 CAL0000102 PMID: 17183478|CGD_REF: CAL0117088 heterozygous diploid, classical genetics null Not recorded vegetative growth: decreased rate C. albicans orf19.4219 ORF RIX7 CAL0000102 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.4219 ORF RIX7 CAL0000102 PMID: 17183478|CGD_REF: CAL0117088 heterozygous diploid, classical genetics null Other C. albicans biofilm formation: decreased biofilm formation quantified by the violet crystal and XTT reduction assays C. albicans orf19.422 ORF SPT20 CAL0005609 PMID: 24732310|CGD_REF: CAL0000173839 homozygous diploid, classical genetics null SC5314 viable C. albicans orf19.422 ORF SPT20 CAL0005609 PMID: 24732310|CGD_REF: CAL0000173839 homozygous diploid, classical genetics null SC5314 virulence: decreased insect infection (G. mellonella infection model) C. albicans orf19.422 ORF SPT20 CAL0005609 PMID: 24732310|CGD_REF: CAL0000173839 homozygous diploid, classical genetics null SC5314 virulence: decreased C. elegans infection C. albicans orf19.422 ORF SPT20 CAL0005609 PMID: 24732310|CGD_REF: CAL0000173839 homozygous diploid, classical genetics null SC5314 virulence: decreased mouse intravenous infection C. albicans orf19.422 ORF SPT20 CAL0005609 PMID: 24732310|CGD_REF: CAL0000173839 homozygous diploid, classical genetics null SC5314 resistance to chemicals: decreased sodium dodecyl sulfate C. albicans orf19.422 ORF SPT20 CAL0005609 PMID: 24732310|CGD_REF: CAL0000173839 homozygous diploid, classical genetics null SC5314 hyperosmotic stress resistance: decreased sodium chloride C. albicans orf19.422 ORF SPT20 CAL0005609 PMID: 24732310|CGD_REF: CAL0000173839 homozygous diploid, classical genetics null SC5314 resistance to chemicals: decreased fluconazole C. albicans orf19.422 ORF SPT20 CAL0005609 PMID: 24732310|CGD_REF: CAL0000173839 homozygous diploid, classical genetics null SC5314 resistance to chemicals: decreased caspofungin C. albicans orf19.422 ORF SPT20 CAL0005609 PMID: 24732310|CGD_REF: CAL0000173839 homozygous diploid, classical genetics null SC5314 resistance to chemicals: decreased amphotericin B C. albicans orf19.422 ORF SPT20 CAL0005609 PMID: 24732310|CGD_REF: CAL0000173839 homozygous diploid, classical genetics null SC5314 hyphal growth: decreased C. albicans orf19.422 ORF SPT20 CAL0005609 PMID: 24732310|CGD_REF: CAL0000173839 homozygous diploid, classical genetics null SC5314 biofilm formation: decreased C. albicans orf19.422 ORF SPT20 CAL0005609 PMID: 24732310|CGD_REF: CAL0000173839 homozygous diploid, classical genetics null SC5314 nuclear position: abnormal C. albicans orf19.422 ORF SPT20 CAL0005609 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 invasive growth: decreased solid SLAD media C. albicans orf19.4221 ORF ORC4 CAL0000132 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.4222 ORF SST2 CAL0000136 PMID: 16400182|CGD_REF: CAL0115369 heterozygous diploid, classical genetics null Not recorded viable C. albicans orf19.4222 ORF SST2 CAL0000136 PMID: 16400182|CGD_REF: CAL0115369 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.4222 ORF SST2 CAL0000136 PMID: 16400182|CGD_REF: CAL0115369 homozygous diploid, classical genetics null Not recorded mating efficiency: decreased C. albicans orf19.4222 ORF SST2 CAL0000136 PMID: 16400182|CGD_REF: CAL0115369 heterozygous diploid, classical genetics null Not recorded mating response: normal reintegrant C. albicans orf19.4222 ORF SST2 CAL0000136 PMID: 16400182|CGD_REF: CAL0115369 heterozygous diploid, classical genetics null Not recorded pheromone sensitivity: normal reintegrant C. albicans orf19.4222 ORF SST2 CAL0000136 PMID: 16400182|CGD_REF: CAL0115369 homozygous diploid, classical genetics null Not recorded pheromone sensitivity: increased alpha factor C. albicans orf19.4223 ORF GCD11 CAL0000138 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.4223 ORF GCD11 CAL0000138 PMID: 12524333|CGD_REF: CAL0080691 homozygous diploid, systematic mutation set (homozygous insertion mutants generated with URA3-ARG4-URA3 (UAU1) cassette) null BWP17 inviable homozygous null mutant strain could not be recovered, suggesting that the gene is essential under the selection conditions C. albicans orf19.4223 ORF GCD11 CAL0000138 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient SC medium C. albicans orf19.4225 ORF LEU3 CAL0000141 PMID: 22359502|CGD_REF: CAL0000144048 homozygous diploid, classical genetics null BWP17 viable insertion mutant, independent SN152 deletion mutant strain also tested C. albicans orf19.4225 ORF LEU3 CAL0000141 PMID: 22359502|CGD_REF: CAL0000144048 homozygous diploid, classical genetics null BWP17 viable insertion mutant, independent SN152 deletion mutant strain also tested C. albicans orf19.4229 ORF CAL0000145 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.423 ORF CAL0005611 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.4230 ORF CAL0000170 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.4231 ORF PTH2 CAL0000174 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.4232 ORF PTH1 CAL0000176 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.4233 ORF THR4 CAL0000179 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.4233 ORF THR4 CAL0000179 PMID: 21135205|CGD_REF: CAL0139967 heterozygous diploid, competitive growth (large-scale identification of genes essential for virulence in mouse) repressible CAI-4 virulence: normal mouse intravenous infection C. albicans orf19.4235 ORF PDE1 CAL0000183 PMID: 17614954|CGD_REF: CAL0118240 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.4235 ORF PDE1 CAL0000183 PMID: 17614954|CGD_REF: CAL0118240 homozygous diploid, classical genetics null Not recorded oxidative stress resistance: decreased hydrogen peroxide C. albicans orf19.4235 ORF PDE1 CAL0000183 PMID: 17614954|CGD_REF: CAL0118240 homozygous diploid, classical genetics null Not recorded metal resistance: decreased cadmium C. albicans orf19.4235 ORF PDE1 CAL0000183 PMID: 20558315|CGD_REF: CAL0125518 homozygous diploid, classical genetics null CAF2-1 filamentous growth: decreased serum-containing or Spider solid media, or embedded in YPS agar filamentous growth is wild-type in liquid media C. albicans orf19.4235 ORF PDE1 CAL0000183 PMID: 20558315|CGD_REF: CAL0125518 homozygous diploid, classical genetics null CAF2-1 chemical compound accumulation: increased 3',5'-cyclic AMP after glucose addition to glucose-starved cells C. albicans orf19.4236 ORF RET2 CAL0000185 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.424 ORF TRP99 CAL0005613 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.424 ORF TRP99 CAL0005613 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 invasive growth: decreased solid SLAD media C. albicans orf19.4240 ORF CAL0000211 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.4240 ORF CAL0000211 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 invasive growth: decreased solid SLAD media C. albicans orf19.4242 ORF CST20 CAL0000217 PMID: 8917572|CGD_REF: CAL0081090 homozygous diploid, classical genetics null CAI-4 germ tube formation: normal solid or liquid serum-containing or liquid Lee's medium C. albicans orf19.4242 ORF CST20 CAL0000217 PMID: 16467475|CGD_REF: CAL0115509 homozygous diploid, classical genetics null Not recorded resistance to enzymatic treatment: decreased beta-1-glucanase C. albicans orf19.4242 ORF CST20 CAL0000217 PMID: 16467475|CGD_REF: CAL0115509 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased Calcofluor White C. albicans orf19.4242 ORF CST20 CAL0000217 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.4242 ORF CST20 CAL0000217 PMID: 12453219|CGD_REF: CAL0080981 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.4242 ORF CST20 CAL0000217 PMID: 8917571|CGD_REF: CAL0081089 heterozygous diploid, classical genetics null Not recorded viable C. albicans orf19.4242 ORF CST20 CAL0000217 PMID: 8917571|CGD_REF: CAL0081089 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.4242 ORF CST20 CAL0000217 PMID: 8917572|CGD_REF: CAL0081090 heterozygous diploid, classical genetics null Not recorded viable C. albicans orf19.4242 ORF CST20 CAL0000217 PMID: 8917572|CGD_REF: CAL0081090 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.4242 ORF CST20 CAL0000217 PMID: 9596738|CGD_REF: CAL0080971 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.4242 ORF CST20 CAL0000217 PMID: 9596738|CGD_REF: CAL0080971 homozygous diploid, classical genetics null CAI-4 hyphal growth: abnormal solid SLAD medium decreased and aberrant hyphal growth C. albicans orf19.4242 ORF CST20 CAL0000217 PMID: 8917572|CGD_REF: CAL0081090 heterozygous diploid, classical genetics null CAI-4 hyphal growth: decreased solid Spider medium heterozygous null and reintegrant show intermediate phenotype between homozygous null and wild-type C. albicans orf19.4242 ORF CST20 CAL0000217 PMID: 8917571|CGD_REF: CAL0081089 homozygous diploid, classical genetics null CAI-4 hyphal growth: decreased solid Spider medium plus galactose, mannose, or raffinose severe decrease C. albicans orf19.4242 ORF CST20 CAL0000217 PMID: 8917571|CGD_REF: CAL0081089 homozygous diploid, classical genetics null CAI-4 hyphal growth: normal liquid media C. albicans orf19.4242 ORF CST20 CAL0000217 PMID: 8917571|CGD_REF: CAL0081089 homozygous diploid, classical genetics null CAI-4 hyphal growth: absent solid Spider medium plus mannitol or sorbitol C. albicans orf19.4242 ORF CST20 CAL0000217 PMID: 8917571|CGD_REF: CAL0081089 homozygous diploid, classical genetics null CAI-4 hyphal growth: normal solid Spider plus glucose or GlcNAc; Lee's; serum-containing; or rice agar media C. albicans orf19.4242 ORF CST20 CAL0000217 PMID: 8917572|CGD_REF: CAL0081090 homozygous diploid, classical genetics null CAI-4 hyphal growth: decreased solid Spider, Lee's, or M199 pH 7 media C. albicans orf19.4242 ORF CST20 CAL0000217 PMID: 8917572|CGD_REF: CAL0081090 homozygous diploid, classical genetics null CAI-4 hyphal growth: decreased solid Spider, Lee's, or M199 pH 7 media C. albicans orf19.4242 ORF CST20 CAL0000217 PMID: 12453219|CGD_REF: CAL0080981 homozygous diploid, classical genetics null Not recorded mating efficiency: decreased C. albicans orf19.4242 ORF CST20 CAL0000217 PMID: 16467475|CGD_REF: CAL0115509 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased Congo Red C. albicans orf19.4242 ORF CST20 CAL0000217 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.4242 ORF CST20 CAL0000217 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.4242 ORF CST20 CAL0000217 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.4242 ORF CST20 CAL0000217 PMID: 8917571|CGD_REF: CAL0081089 homozygous diploid, classical genetics null Not recorded virulence: decreased exhibits decreased kidney colonization mouse intravenous infection C. albicans orf19.4242 ORF CST20 CAL0000217 PMID: 8917571|CGD_REF: CAL0081089 heterozygous diploid, classical genetics null Not recorded virulence: normal mouse intravenous infection C. albicans orf19.4242 ORF CST20 CAL0000217 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.4243 ORF CAL0000220 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.4243 ORF CAL0000220 PMID: 14663094|CGD_REF: CAL0080633 homozygous diploid, systematic mutation set (homozygous insertion mutants generated with URA3-ARG4-URA3 (UAU1) cassette) null BWP17 viable C. albicans orf19.4244 ORF CAL0000221 PMID: 14663094|CGD_REF: CAL0080633 homozygous diploid, systematic mutation set (homozygous insertion mutants generated with URA3-ARG4-URA3 (UAU1) cassette) null BWP17 viable C. albicans orf19.4246 ORF CAL0000225 PMID: 12773383|CGD_REF: CAL0087974 heterozygous diploid, classical genetics (haploinsufficient phenotype assay) null CAI-4 viable heterozygous transposon insertion C. albicans orf19.4246 ORF CAL0000225 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.4246 ORF CAL0000225 PMID: 12773383|CGD_REF: CAL0087974 heterozygous diploid, classical genetics (haploinsufficient phenotype assay) null CAI-4 filamentous growth: decreased solid Spider medium heterozygous transposon insertion C. albicans orf19.4247 ORF CAL0000226 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 invasive growth: decreased solid SLAD media C. albicans orf19.4248 ORF CAL0000227 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.4248 ORF CAL0000227 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.4248 ORF CAL0000227 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.4248 ORF CAL0000227 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.4248 ORF CAL0000227 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.425 ORF CAL0005616 PMID: 14663094|CGD_REF: CAL0080633 homozygous diploid, systematic mutation set (homozygous insertion mutants generated with URA3-ARG4-URA3 (UAU1) cassette) null BWP17 viable C. albicans orf19.4251 ORF ZCF22 CAL0000249 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 invasive growth: decreased solid SLAD media C. albicans orf19.4252 ORF CAL0000253 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.4255 ORF ECM331 CAL0000259 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.4255 ORF ECM331 CAL0000259 PMID: 18765290|CGD_REF: CAL0119430 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.4257 ORF INT1 CAL0000261 PMID: 14663094|CGD_REF: CAL0080633 homozygous diploid, systematic mutation set (homozygous insertion mutants generated with URA3-ARG4-URA3 (UAU1) cassette) null BWP17 viable C. albicans orf19.4257 ORF INT1 CAL0000261 PMID: 10847632|CGD_REF: CAL0081454 heterozygous diploid, classical genetics null Other C. albicans viable C. albicans orf19.4257 ORF INT1 CAL0000261 PMID: 10847632|CGD_REF: CAL0081454 homozygous diploid, classical genetics null Other C. albicans viable C. albicans orf19.4257 ORF INT1 CAL0000261 PMID: 11694587|CGD_REF: CAL0080801 heterozygous diploid, classical genetics null Not recorded viable C. albicans orf19.4257 ORF INT1 CAL0000261 PMID: 11694587|CGD_REF: CAL0080801 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.4257 ORF INT1 CAL0000261 PMID: 9478896|CGD_REF: CAL0081448 homozygous diploid, classical genetics null Not recorded adhesion: decreased adhesion to human epithelial (HeLa) cells specific reduced by 39% relative to wild type C. albicans orf19.4257 ORF INT1 CAL0000261 PMID: 11694587|CGD_REF: CAL0080801 homozygous diploid, classical genetics null Not recorded budding pattern: abnormal increased budding in a bipolar pattern, compared to wild type and reintegrant strains, which each show roughly equivalent amounts of bipolar and axial budding C. albicans orf19.4257 ORF INT1 CAL0000261 PMID: 10600356|CGD_REF: CAL0081452 homozygous diploid, classical genetics null CAF2-1 filamentous growth: decreased orally infected mice, antibiotic pretreatment decreased filamentous growth in ileum mouse gastrointestinal tract infection C. albicans orf19.4257 ORF INT1 CAL0000261 PMID: 9478896|CGD_REF: CAL0081448 homozygous diploid, classical genetics null CAI-4 filamentous growth: decreased milk-Tween agar and on Spider medium C. albicans orf19.4257 ORF INT1 CAL0000261 PMID: 10600356|CGD_REF: CAL0081452 homozygous diploid, classical genetics null CAF2-1 virulence: decreased orally infected mice, antibiotic pretreatment decreased cecal colonization mouse gastrointestinal tract infection C. albicans orf19.4257 ORF INT1 CAL0000261 PMID: 10847632|CGD_REF: CAL0081454 homozygous diploid, classical genetics null Other C. albicans virulence: decreased mouse oral infection with oral bacitracin/streptomycin pre-treatment decreased cecal colonization, with or without pre-treatment with parenteral lipopolysaccharide mouse gastrointestinal tract infection C. albicans orf19.4257 ORF INT1 CAL0000261 PMID: 10847632|CGD_REF: CAL0081454 heterozygous diploid, classical genetics null Other C. albicans virulence: decreased mouse oral infection with oral bacitracin/streptomycin pre-treatment decreased cecal colonization; defect of reintegrant similar to that of homozygous null mutant mouse gastrointestinal tract infection C. albicans orf19.4257 ORF INT1 CAL0000261 PMID: 10600356|CGD_REF: CAL0081452 heterozygous diploid, classical genetics null CAF2-1 virulence: decreased orally infected mice, antibiotic pretreatment heterozygous null and reintegrant show decreased cecal colonization, similar to that by null mutant mouse gastrointestinal tract infection C. albicans orf19.4257 ORF INT1 CAL0000261 PMID: 10444345|CGD_REF: CAL0081451 homozygous diploid, classical genetics null Not recorded virulence: decreased increased kidney colonization but decreased deep tissue invasion mouse intravenous infection C. albicans orf19.4257 ORF INT1 CAL0000261 PMID: 10444345|CGD_REF: CAL0081451 heterozygous diploid, classical genetics null Not recorded virulence: decreased virulence is intermediate between that of the homozygous null mutant and wild type mouse intravenous infection C. albicans orf19.4258 ORF CAL0000262 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.4258 ORF CAL0000262 PMID: 19623926|CGD_REF: CAL0124054 heterozygous diploid, competitive growth (haploinsufficient phenotype assay, barcode deletion set) null SC5314 resistance to chemicals: decreased cordycepin C. albicans orf19.4258 ORF CAL0000262 PMID: 19623926|CGD_REF: CAL0124054 heterozygous diploid, competitive growth (haploinsufficient phenotype assay, barcode deletion set) null SC5314 resistance to chemicals: decreased cordycepin C. albicans orf19.4258 ORF CAL0000262 PMID: 19623926|CGD_REF: CAL0124054 heterozygous diploid, competitive growth (haploinsufficient phenotype assay, barcode deletion set) null SC5314 resistance to chemicals: decreased parnafungin C. albicans orf19.4262 ORF CAL0000283 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.4265 ORF UAP1 CAL0000289 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.4266 ORF SPR28 CAL0000291 PMID: 12181342|CGD_REF: CAL0080842 homozygous diploid, classical genetics null Not recorded viable no apparent phenotype C. albicans orf19.4266 ORF SPR28 CAL0000291 PMID: 16002645|CGD_REF: CAL0114398 homozygous diploid, classical genetics null Not recorded chlamydospore formation: normal C. albicans orf19.4268 ORF UTP13 CAL0000293 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.4269 ORF CAL0000294 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.4270 ORF MNN13 CAL0000309 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.4270 ORF MNN13 CAL0000309 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.4270 ORF MNN13 CAL0000309 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.4270 ORF MNN13 CAL0000309 PMID: 23886038|CGD_REF: CAL0000172548 homozygous diploid, classical genetics null CAI-4 viable C. albicans orf19.4270 ORF MNN13 CAL0000309 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient YPD medium C. albicans orf19.4270 ORF MNN13 CAL0000309 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient SC medium C. albicans orf19.4270 ORF MNN13 CAL0000309 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.4275 ORF RAD9 CAL0000322 PMID: 17182857|CGD_REF: CAL0117321 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.4275 ORF RAD9 CAL0000322 PMID: 17182857|CGD_REF: CAL0117321 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased methyl methanesulfonate C. albicans orf19.4275 ORF RAD9 CAL0000322 PMID: 17182857|CGD_REF: CAL0117321 homozygous diploid, classical genetics null Not recorded chemical compound accumulation: normal hydroxyurea C. albicans orf19.4279 ORF MNN1 CAL0000325 PMID: 23886038|CGD_REF: CAL0000172548 homozygous diploid, classical genetics null CAI-4 viable C. albicans orf19.428 ORF CAL0005622 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.4282 ORF IFH1 CAL0000350 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.4284 ORF BUR2 CAL0000355 PMID: 14663094|CGD_REF: CAL0080633 homozygous diploid, systematic mutation set (homozygous insertion mutants generated with URA3-ARG4-URA3 (UAU1) cassette) null BWP17 viable C. albicans orf19.4284 ORF BUR2 CAL0000355 PMID: 14500538|CGD_REF: CAL0081606 homozygous diploid, classical genetics null Not recorded viable liquid YPD at 37 deg C wild-type growth rate C. albicans orf19.4284 ORF BUR2 CAL0000355 PMID: 14500538|CGD_REF: CAL0081606 homozygous diploid, classical genetics null Not recorded adhesion: normal adhesion to human buccal epithelial cells C. albicans orf19.4284 ORF BUR2 CAL0000355 PMID: 14500538|CGD_REF: CAL0081606 homozygous diploid, classical genetics null CAI-4 hyphal growth: normal solid M199 or Spider media C. albicans orf19.4284 ORF BUR2 CAL0000355 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.4284 ORF BUR2 CAL0000355 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: abnormal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.4284 ORF BUR2 CAL0000355 PMID: 23856128|CGD_REF: CAL0000172540 homozygous diploid, classical genetics null BWP17 resistance to chemicals: decreased propolis C. albicans orf19.4284 ORF BUR2 CAL0000355 PMID: 14500538|CGD_REF: CAL0081606 homozygous diploid, classical genetics null Not recorded virulence: normal mouse intravenous infection C. albicans orf19.4284 ORF BUR2 CAL0000355 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: decreased rate liquid synthetic complete medium C. albicans orf19.4284 ORF BUR2 CAL0000355 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.4287 ORF CAL0000359 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.4288 ORF CTA7 CAL0000360 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 invasive growth: decreased solid SLAD media C. albicans orf19.429 ORF CAL0005626 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.429 ORF CAL0005626 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 invasive growth: decreased solid SLAD media C. albicans orf19.4290 ORF TRR1 CAL0000375 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.4290 ORF TRR1 CAL0000375 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient YPD medium C. albicans orf19.4290 ORF TRR1 CAL0000375 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient SC medium C. albicans orf19.4290 ORF TRR1 CAL0000375 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient SLAD medium C. albicans orf19.4290 ORF TRR1 CAL0000375 PMID: 21135205|CGD_REF: CAL0139967 heterozygous diploid, competitive growth (large-scale identification of genes essential for virulence in mouse) repressible CAI-4 virulence: normal mouse intravenous infection C. albicans orf19.4292 ORF CAL0000381 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: decreased growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.4292 ORF CAL0000381 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: abnormal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.4292 ORF CAL0000381 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.4292 ORF CAL0000381 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.4293 ORF CAL0000383 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.4295 ORF CAL0000387 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.4297 ORF CKB2 CAL0000389 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.4297 ORF CKB2 CAL0000389 PMID: 15813744|CGD_REF: CAL0104042 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.4297 ORF CKB2 CAL0000389 PMID: 23856128|CGD_REF: CAL0000172540 homozygous diploid, classical genetics null BWP17 resistance to chemicals: decreased propolis C. albicans orf19.4299 ORF MSW1 CAL0000390 PMID: 12524333|CGD_REF: CAL0080691 homozygous diploid, systematic mutation set (homozygous insertion mutants generated with URA3-ARG4-URA3 (UAU1) cassette) null BWP17 inviable homozygous null mutant strain could not be recovered, suggesting that the gene is essential under the selection conditions C. albicans orf19.430 ORF YPT53 CAL0005648 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.430 ORF YPT53 CAL0005648 PMID: 23709183|CGD_REF: CAL0000172370 homozygous diploid, classical genetics null BWP17 viable C. albicans orf19.4304 ORF GAP1 CAL0000889 PMID: 12949183|CGD_REF: CAL0081072 heterozygous diploid, classical genetics null Not recorded viable C. albicans orf19.4304 ORF GAP1 CAL0000889 PMID: 12949183|CGD_REF: CAL0081072 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.4304 ORF GAP1 CAL0000889 PMID: 12949183|CGD_REF: CAL0081072 heterozygous diploid, classical genetics null Other C. albicans filamentous growth: decreased solid SLAD medium phenotype intermediate between wild type and homozygous null mutant C. albicans orf19.4304 ORF GAP1 CAL0000889 PMID: 12949183|CGD_REF: CAL0081072 heterozygous diploid, classical genetics null Other C. albicans filamentous growth: decreased liquid media plus GlcNAc C. albicans orf19.4304 ORF GAP1 CAL0000889 PMID: 12949183|CGD_REF: CAL0081072 homozygous diploid, classical genetics null Other C. albicans filamentous growth: decreased liquid media plus GlcNAc C. albicans orf19.4304 ORF GAP1 CAL0000889 PMID: 12949183|CGD_REF: CAL0081072 homozygous diploid, classical genetics null Other C. albicans filamentous growth: decreased solid SLAD medium C. albicans orf19.4304 ORF GAP1 CAL0000889 PMID: 12949183|CGD_REF: CAL0081072 homozygous diploid, classical genetics null Other C. albicans filamentous growth: decreased solid Spider plus mannitol C. albicans orf19.4304 ORF GAP1 CAL0000889 PMID: 12949183|CGD_REF: CAL0081072 heterozygous diploid, classical genetics null Other C. albicans filamentous growth: normal solid Spider plus mannitol C. albicans orf19.4304 ORF GAP1 CAL0000889 PMID: 12949183|CGD_REF: CAL0081072 homozygous diploid, classical genetics null Other C. albicans filamentous growth: decreased C. albicans orf19.4304 ORF GAP1 CAL0000889 PMID: 12949183|CGD_REF: CAL0081072 homozygous diploid, classical genetics null Not recorded virulence: normal mouse intravenous infection C. albicans orf19.4304 ORF GAP1 CAL0000889 PMID: 23572557|CGD_REF: CAL0000158900 homozygous diploid, classical genetics null BWP17 resistance to chemicals: decreased fluconazole RPMI+MOPS+Histidine medium , 6 hours without shaking at 37 degrees C 24 hr fluconazole treatment in 96 well plates C. albicans orf19.4304 ORF GAP1 CAL0000889 PMID: 23572557|CGD_REF: CAL0000158900 homozygous diploid, classical genetics null BWP17 adhesion: increased Fluxion Bioflux 200, equipped with a microscope, was used for adherence analysis allowing a constant flow of cells through microfluidic channels C. albicans orf19.4306 ORF CAL0000892 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.4307 ORF CAL0000893 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.4308 ORF HSL1 CAL0000894 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.4308 ORF HSL1 CAL0000894 PMID: 15659158|CGD_REF: CAL0082298 homozygous diploid, classical genetics null Not recorded viable YPD medium at 30 deg C wild-type growth rate C. albicans orf19.4308 ORF HSL1 CAL0000894 PMID: 14769857|CGD_REF: CAL0080845 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.4308 ORF HSL1 CAL0000894 PMID: 15659158|CGD_REF: CAL0082298 homozygous diploid, classical genetics null CAI-4 hyphal growth: increased rate increased hyphal cell length C. albicans orf19.4308 ORF HSL1 CAL0000894 PMID: 15659158|CGD_REF: CAL0082298 homozygous diploid, classical genetics null CAI-4 hyphal growth: normal solid serum-containing or M199 media C. albicans orf19.4308 ORF HSL1 CAL0000894 PMID: 15659158|CGD_REF: CAL0082298 homozygous diploid, classical genetics reduction of function hsl1-K94M (mutation in predicted kinase domain) Not recorded cell shape: abnormal yeast-form cells are elongated; mutant protein expressed in homozygous null mutant background C. albicans orf19.4308 ORF HSL1 CAL0000894 PMID: 15659158|CGD_REF: CAL0082298 homozygous diploid, classical genetics null Not recorded cell shape: abnormal yeast-form cells are elongated C. albicans orf19.4308 ORF HSL1 CAL0000894 PMID: 15659158|CGD_REF: CAL0082298 homozygous diploid, classical genetics null CAI-4 invasive growth: increased solid YPD medium increased invasive growth on C. albicans orf19.4308 ORF HSL1 CAL0000894 PMID: 14769857|CGD_REF: CAL0080845 homozygous diploid, classical genetics null Not recorded cellular morphology: normal at high cell density C. albicans orf19.4308 ORF HSL1 CAL0000894 PMID: 14769857|CGD_REF: CAL0080845 heterozygous diploid, classical genetics repressible Not recorded cellular morphology: normal wild-type cell morphology at high cell density C. albicans orf19.4308 ORF HSL1 CAL0000894 PMID: 14769857|CGD_REF: CAL0080845 heterozygous diploid, classical genetics repressible Not recorded pseudohyphal growth: abnormal constitutive pseudohyphal morphology at low cell density C. albicans orf19.4308 ORF HSL1 CAL0000894 PMID: 14769857|CGD_REF: CAL0080845 homozygous diploid, classical genetics null Not recorded pseudohyphal growth: increased pseudohyphal growth is constitutive at low cell density C. albicans orf19.4308 ORF HSL1 CAL0000894 PMID: 15659158|CGD_REF: CAL0082298 homozygous diploid, classical genetics null CAI-4 filamentous growth: increased non-inducing conditions (YPD solid medium) C. albicans orf19.4308 ORF HSL1 CAL0000894 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: decreased growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.4308 ORF HSL1 CAL0000894 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: abnormal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.4308 ORF HSL1 CAL0000894 PMID: 15659158|CGD_REF: CAL0082298 homozygous diploid, classical genetics null Not recorded virulence: decreased exhibits decreased kidney colonization mouse intravenous infection C. albicans orf19.4308 ORF HSL1 CAL0000894 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: decreased rate liquid synthetic complete medium C. albicans orf19.4308 ORF HSL1 CAL0000894 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.4309 ORF GRP2 CAL0000895 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.431 ORF ZCF2 CAL0005650 PMID: 15964282|CGD_REF: CAL0114274 homozygous diploid, systematic mutation set (split-marker transposon insertion strategy to disrupt both alleles) null BWP17 viable C. albicans orf19.431 ORF ZCF2 CAL0005650 PMID: 15964282|CGD_REF: CAL0114274 homozygous diploid, systematic mutation set (split-marker transposon insertion strategy to disrupt both alleles) null BWP17 biofilm formation: normal C. albicans orf19.431 ORF ZCF2 CAL0005650 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.431 ORF ZCF2 CAL0005650 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.431 ORF ZCF2 CAL0005650 PMID: 22073120|CGD_REF: CAL0000143592 homozygous diploid, classical genetics null BWP17 viable C. albicans orf19.431 ORF ZCF2 CAL0005650 PMID: 22073120|CGD_REF: CAL0000143592 homozygous diploid, classical genetics null BWP17 colony appearance: abnormal increased colony wrinkling C. albicans orf19.431 ORF ZCF2 CAL0005650 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.431 ORF ZCF2 CAL0005650 PMID: 23417561|CGD_REF: CAL0000158590 homozygous diploid, classical genetics null SC5314 resistance to chemicals: decreased sulfite C. albicans orf19.431 ORF ZCF2 CAL0005650 PMID: 23417561|CGD_REF: CAL0000158590 homozygous diploid, classical genetics null SC5314 resistance to chemicals: decreased cysteine C. albicans orf19.431 ORF ZCF2 CAL0005650 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.4310 ORF CAL0000914 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient YNB medium C. albicans orf19.4311 ORF YNK1 CAL0000917 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.4312 ORF CAL0000920 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.4312 ORF CAL0000920 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.4312 ORF CAL0000920 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: abnormal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.4312 ORF CAL0000920 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: decreased rate liquid synthetic complete medium C. albicans orf19.4312 ORF CAL0000920 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.4316 ORF CAL0000924 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.4316 ORF CAL0000924 PMID: 19289605|CGD_REF: CAL0122500 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.4316 ORF CAL0000924 PMID: 19289605|CGD_REF: CAL0122500 homozygous diploid, classical genetics null Not recorded utilization of carbon source: absent acetic acid C. albicans orf19.4316 ORF CAL0000924 PMID: 19289605|CGD_REF: CAL0122500 homozygous diploid, classical genetics null Not recorded utilization of carbon source: absent oleic acid C. albicans orf19.4316 ORF CAL0000924 PMID: 19289605|CGD_REF: CAL0122500 homozygous diploid, classical genetics null Not recorded utilization of carbon source: absent ethanol C. albicans orf19.4317 ORF GRE3 CAL0000925 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.4318 ORF MIG1 CAL0000926 PMID: 11532938|CGD_REF: CAL0080745 homozygous diploid, classical genetics null Not recorded germ tube formation: normal serum-containing medium C. albicans orf19.4318 ORF MIG1 CAL0000926 PMID: 11737641|CGD_REF: CAL0080636 homozygous diploid, classical genetics null Not recorded respiratory metabolism: abnormal decreased oxygen utilization C. albicans orf19.4318 ORF MIG1 CAL0000926 PMID: 11737641|CGD_REF: CAL0080636 homozygous diploid, classical genetics null Not recorded vegetative growth: decreased rate C. albicans orf19.4318 ORF MIG1 CAL0000926 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.4318 ORF MIG1 CAL0000926 PMID: 15964282|CGD_REF: CAL0114274 homozygous diploid, systematic mutation set (split-marker transposon insertion strategy to disrupt both alleles) null BWP17 viable C. albicans orf19.4318 ORF MIG1 CAL0000926 PMID: 11532939|CGD_REF: CAL0081163 homozygous diploid, classical genetics null Not recorded viable no obvious phenotype C. albicans orf19.4318 ORF MIG1 CAL0000926 PMID: 10629176|CGD_REF: CAL0081283 homozygous diploid, classical genetics null RM1000 viable wild-type growth rate C. albicans orf19.4318 ORF MIG1 CAL0000926 PMID: 11737641|CGD_REF: CAL0080636 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.4318 ORF MIG1 CAL0000926 PMID: 19463063|CGD_REF: CAL0123630 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.4318 ORF MIG1 CAL0000926 PMID: 20041210|CGD_REF: CAL0124764 homozygous diploid, systematic mutation set null SN152 resistance to chemicals: decreased rapamycin strongly sensitive C. albicans orf19.4318 ORF MIG1 CAL0000926 PMID: 10629176|CGD_REF: CAL0081283 homozygous diploid, classical genetics null RM1000 hyphal growth: normal C. albicans orf19.4318 ORF MIG1 CAL0000926 PMID: 15964282|CGD_REF: CAL0114274 homozygous diploid, systematic mutation set (split-marker transposon insertion strategy to disrupt both alleles) null BWP17 biofilm formation: normal C. albicans orf19.4318 ORF MIG1 CAL0000926 PMID: 14507372|CGD_REF: CAL0088818 heterozygous diploid, large-scale survey (large-scale identification of essential genes by gene replacement and conditional expression (GRACE) method) repressible CAI-4 inviable one allele is deleted and the other is placed under repressible Tet promoter C. albicans orf19.4318 ORF MIG1 CAL0000926 PMID: 20041210|CGD_REF: CAL0124764 homozygous diploid, systematic mutation set null SN152 resistance to chemicals: decreased caffeine severely sensitive C. albicans orf19.4318 ORF MIG1 CAL0000926 PMID: 19463063|CGD_REF: CAL0123630 homozygous diploid, systematic mutation set (split-marker transposon insertion strategy to disrupt both alleles) null BWP17 virulence: normal Toll mutant D. melanogaster invasive infection insect infection C. albicans orf19.4318 ORF MIG1 CAL0000926 PMID: 10629176|CGD_REF: CAL0081283 homozygous diploid, classical genetics null RM1000 virulence: normal mouse intravenous infection C. albicans orf19.432 ORF CAL0005652 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.4322 ORF DAP2 CAL0000950 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.4324 ORF CAL0000955 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.4325 ORF CAL0000957 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.4326 ORF CAL0000958 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.4326 ORF CAL0000958 PMID: 21135205|CGD_REF: CAL0139967 heterozygous diploid, competitive growth (large-scale identification of genes essential for virulence in mouse) repressible CAI-4 virulence: decreased mouse intravenous infection C. albicans orf19.4328 ORF CCC2 CAL0000959 PMID: 19023418|CGD_REF: CAL0121072 homozygous diploid, classical genetics null Not recorded utilization of iron source: absent ferritin C. albicans orf19.4328 ORF CCC2 CAL0000959 PMID: 12067343|CGD_REF: CAL0080829 heterozygous diploid, classical genetics null Not recorded utilization of iron source: normal wild-type growth in presence of iron chelator; wild-type use of hemin or hemoglobin iron source C. albicans orf19.4328 ORF CCC2 CAL0000959 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.4328 ORF CCC2 CAL0000959 PMID: 12067343|CGD_REF: CAL0080829 heterozygous diploid, classical genetics null Not recorded viable C. albicans orf19.4328 ORF CCC2 CAL0000959 PMID: 12067343|CGD_REF: CAL0080829 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.4328 ORF CCC2 CAL0000959 PMID: 12067343|CGD_REF: CAL0080829 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased iron chelators C. albicans orf19.4328 ORF CCC2 CAL0000959 PMID: 16954314|CGD_REF: CAL0116835 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased fluconazole reversible by iron supplementation C. albicans orf19.4328 ORF CCC2 CAL0000959 PMID: 12067343|CGD_REF: CAL0080829 homozygous diploid, classical genetics null Not recorded virulence: normal wild-type kidney colonization mouse intravenous infection C. albicans orf19.433 ORF CAL0005654 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.433 ORF CAL0005654 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.433 ORF CAL0005654 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.433 ORF CAL0005654 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.4332 ORF CAL0000983 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 invasive growth: decreased solid SLAD media C. albicans orf19.4336 ORF RPS5 CAL0000989 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.4337 ORF CAL0000990 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.4339 ORF VPS4 CAL0000992 PMID: 18814053|CGD_REF: CAL0120281 homozygous diploid, classical genetics null Not recorded utilization of carbon source: decreased polysorbate 80 solid medium C. albicans orf19.4339 ORF VPS4 CAL0000992 PMID: 17506830|CGD_REF: CAL0118319 homozygous diploid, classical genetics null Not recorded vacuolar morphology: abnormal vacuoles are enlarged, similar to the class E vacuolar morphology of S. cerevisiae vps4 null mutants C. albicans orf19.4339 ORF VPS4 CAL0000992 PMID: 15590834|CGD_REF: CAL0082485 homozygous diploid, classical genetics null Not recorded vacuolar transport: decreased defect in multivesicular body (MVB) transport to the vacuole C. albicans orf19.4339 ORF VPS4 CAL0000992 PMID: 15590834|CGD_REF: CAL0082485 heterozygous diploid, classical genetics null Not recorded viable C. albicans orf19.4339 ORF VPS4 CAL0000992 PMID: 15590834|CGD_REF: CAL0082485 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.4339 ORF VPS4 CAL0000992 PMID: 17506830|CGD_REF: CAL0118319 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.4339 ORF VPS4 CAL0000992 PMID: 18814053|CGD_REF: CAL0120281 heterozygous diploid, classical genetics null CAF2-1 viable C. albicans orf19.4339 ORF VPS4 CAL0000992 PMID: 18814053|CGD_REF: CAL0120281 homozygous diploid, classical genetics null CAF2-1 viable C. albicans orf19.4339 ORF VPS4 CAL0000992 PMID: 19819358|CGD_REF: CAL0124401 homozygous diploid, classical genetics null BWP17 filamentous growth: abnormal increased frequency of branching, characteristic of class E vacuolar mutants C. albicans orf19.4339 ORF VPS4 CAL0000992 PMID: 19819358|CGD_REF: CAL0124401 homozygous diploid, classical genetics null BWP17 biofilm formation: abnormal denser biofilm with increased resistance to capsofungin C. albicans orf19.4339 ORF VPS4 CAL0000992 PMID: 18814053|CGD_REF: CAL0120281 homozygous diploid, classical genetics null CAF2-1 protein secretion: decreased BSA agar Sap2p secretion is decreased; BSA degradation is increased Sap2p C. albicans orf19.4339 ORF VPS4 CAL0000992 PMID: 18814053|CGD_REF: CAL0120281 homozygous diploid, classical genetics null CAF2-1 protein secretion: decreased liquid RPMI at 37 deg C Sap4-6p C. albicans orf19.4339 ORF VPS4 CAL0000992 PMID: 17506830|CGD_REF: CAL0118319 homozygous diploid, classical genetics null Not recorded protein secretion: decreased decreased extracellular protease activity C. albicans orf19.4339 ORF VPS4 CAL0000992 PMID: 18814053|CGD_REF: CAL0120281 homozygous diploid, classical genetics null Not recorded protein secretion: decreased decreased secreted lipase activity C. albicans orf19.4339 ORF VPS4 CAL0000992 PMID: 15590834|CGD_REF: CAL0082485 homozygous diploid, classical genetics null BWP17 filamentous growth: normal liquid media with serum C. albicans orf19.4339 ORF VPS4 CAL0000992 PMID: 15590834|CGD_REF: CAL0082485 homozygous diploid, classical genetics null BWP17 filamentous growth: decreased solid M199 medium, pH 8 C. albicans orf19.4339 ORF VPS4 CAL0000992 PMID: 22427429|CGD_REF: CAL0000156990 homozygous diploid, classical genetics null BWP17 protein/peptide modification: absent mutants don't process RIM8-HA RIM8-HA C. albicans orf19.4339 ORF VPS4 CAL0000992 PMID: 22427429|CGD_REF: CAL0000156990 homozygous diploid, classical genetics null BWP17 protein/peptide modification: increased mutant constitutively processes Rim101 Rim101p C. albicans orf19.4339 ORF VPS4 CAL0000992 PMID: 22427429|CGD_REF: CAL0000156990 homozygous diploid, classical genetics null BWP17 protein/peptide modification: abnormal defective for RIM8-HA-processing RIM8-HA C. albicans orf19.4339 ORF VPS4 CAL0000992 PMID: 18814053|CGD_REF: CAL0120281 homozygous diploid, classical genetics null Not recorded virulence: decreased decreased kidney colonization, and kidney microabscesses are absent mouse intravenous infection C. albicans orf19.4339 ORF VPS4 CAL0000992 PMID: 18814053|CGD_REF: CAL0120281 heterozygous diploid, classical genetics null Not recorded virulence: decreased virulence is intermediate between that of the homozygous null mutant and wild type mouse intravenous infection C. albicans orf19.4339 ORF VPS4 CAL0000992 PMID: 20581294|CGD_REF: CAL0125802 homozygous diploid, classical genetics null BWP17 metal resistance: decreased lithium chloride (150 mM) YPD plus 150 mM lithium chloride C. albicans orf19.4339 ORF VPS4 CAL0000992 PMID: 20581294|CGD_REF: CAL0125802 homozygous diploid, classical genetics null BWP17 filamentous growth: abnormal C. albicans orf19.4339 ORF VPS4 CAL0000992 PMID: 20581294|CGD_REF: CAL0125802 homozygous diploid, classical genetics null BWP17 resistance to chemicals: decreased iron chelators YPD plus 150 micromolar bathophenanthrolinedisulfonic acid (BPS) C. albicans orf19.434 ORF PRD1 CAL0005656 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.434 ORF PRD1 CAL0005656 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient YPD medium C. albicans orf19.434 ORF PRD1 CAL0005656 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient SC medium C. albicans orf19.434 ORF PRD1 CAL0005656 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient SLAD medium C. albicans orf19.4341 ORF CAL0001012 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.4342 ORF SUT1 CAL0001013 CGD_REF: CAL0000173071 homozygous diploid, classical genetics null C. albicans virulence: decreased attenuated for invasive infection C. albicans orf19.4346 ORF CAL0001016 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.4347 ORF CAL0001018 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.4348 ORF MED14 CAL0001020 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.4353 ORF ULP2 CAL0001037 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.4353 ORF ULP2 CAL0001037 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.4353 ORF ULP2 CAL0001037 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.4353 ORF ULP2 CAL0001037 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: decreased rate liquid synthetic complete medium C. albicans orf19.4353 ORF ULP2 CAL0001037 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.4356 ORF HGT3 CAL0001043 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.4362 ORF CAL0001067 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.4362 ORF CAL0001067 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.4362 ORF CAL0001067 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.4362 ORF CAL0001067 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.4362 ORF CAL0001067 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.4363 ORF SGD1 CAL0001070 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.4363 ORF SGD1 CAL0001070 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient YPD medium C. albicans orf19.4363 ORF SGD1 CAL0001070 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient YNB medium C. albicans orf19.4363 ORF SGD1 CAL0001070 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient SLAD medium C. albicans orf19.4365 ORF CAL0001075 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.4367 ORF SMC1 CAL0001080 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.4368 ORF CAL0001082 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.4369 ORF CAL0001084 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.4369 ORF CAL0001084 PMID: 14663094|CGD_REF: CAL0080633 homozygous diploid, systematic mutation set (homozygous insertion mutants generated with URA3-ARG4-URA3 (UAU1) cassette) null BWP17 viable C. albicans orf19.437 ORF GRS1 CAL0005660 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.4370 ORF CAL0001100 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.4371 ORF TAL1 CAL0001103 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.4372 ORF CAL0001105 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.4373 ORF CAL0001108 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.4374 ORF PRP42 CAL0001111 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.4375 ORF CAL0001114 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.4375.1 ORF RPS30 CAF0007010 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient YPD medium C. albicans orf19.4375.1 ORF RPS30 CAF0007010 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient SC medium C. albicans orf19.4375.1 ORF RPS30 CAF0007010 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient YNB medium C. albicans orf19.4375.1 ORF RPS30 CAF0007010 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient SLAD medium C. albicans orf19.4376 ORF CAL0001117 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.4376 ORF CAL0001117 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.4376 ORF CAL0001117 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.4376 ORF CAL0001117 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.4376 ORF CAL0001117 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.4378 ORF PPH3 CAL0001121 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.4378 ORF PPH3 CAL0001121 PMID: 21890819|CGD_REF: CAL0000142895 homozygous diploid, classical genetics null pph3::ARG4/pph3::HIS1 BWP17 viable C. albicans orf19.4378 ORF PPH3 CAL0001121 PMID: 21890819|CGD_REF: CAL0000142895 homozygous diploid, classical genetics null pph3::ARG4/pph3::HIS1 BWP17 resistance to chemicals: decreased methyl methanesulfonate C. albicans orf19.4378 ORF PPH3 CAL0001121 PMID: 21890819|CGD_REF: CAL0000142895 homozygous diploid, classical genetics null pph3::ARG4/pph3::HIS1 BWP17 resistance to chemicals: decreased cisplatin C. albicans orf19.4378 ORF PPH3 CAL0001121 PMID: 21890819|CGD_REF: CAL0000142895 homozygous diploid, classical genetics null pph3::ARG4/pph3::HIS1 BWP17 UV resistance: decreased C. albicans orf19.4378 ORF PPH3 CAL0001121 PMID: 22606354|CGD_REF: CAL0000157313 homozygous diploid, classical genetics null BWP17 protein/peptide modification: increased mutant displays Rad53 hyperphosphorylation Rad53 C. albicans orf19.4378 ORF PPH3 CAL0001121 PMID: 23083206|CGD_REF: CAL0000158035 homozygous diploid, classical genetics null RM1000 resistance to chemicals: decreased methyl methanesulfonate (0.015%) C. albicans orf19.4378 ORF PPH3 CAL0001121 PMID: 23083206|CGD_REF: CAL0000158035 homozygous diploid, classical genetics null RM1000 resistance to chemicals: decreased hydroxyurea (40 mM) C. albicans orf19.4378 ORF PPH3 CAL0001121 PMID: 23083206|CGD_REF: CAL0000158035 homozygous diploid, classical genetics null RM1000 filamentous growth: increased liquid Lee?s, SLAD, Spider media, or YPD medium containing 10% FBS C. albicans orf19.4381 ORF VTC3 CAL0001140 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.4382 ORF CAL0001142 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.4382 ORF CAL0001142 PMID: 21135205|CGD_REF: CAL0139967 heterozygous diploid, large-scale survey (large-scale identification of genes essential for virulence in mouse) repressible CAI-4 virulence: absent mouse intravenous infection C. albicans orf19.4384 ORF HXT5 CAL0001148 PMID: 21414038|CGD_REF: CAL0141808 homozygous diploid, classical genetics null BWP17 viable C. albicans orf19.4384 ORF HXT5 CAL0001148 PMID: 21414038|CGD_REF: CAL0141808 homozygous diploid, classical genetics null BWP17 biofilm formation: normal C. albicans orf19.4388 ORF CAL0001155 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.4392 ORF DEM1 CAL0001175 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.4395 ORF CAL0001184 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.4396 ORF CAL0001186 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.4400 ORF CAL0001706 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 invasive growth: decreased solid SLAD media C. albicans orf19.4401 ORF YVH1 CAL0001708 PMID: 16000712|CGD_REF: CAL0114380 homozygous diploid, classical genetics null CAI-4 germ tube formation: normal serum-containing medium C. albicans orf19.4401 ORF YVH1 CAL0001708 PMID: 16000712|CGD_REF: CAL0114380 heterozygous diploid, classical genetics overexpression Not recorded vegetative growth: increased rate faster than wild-type growth rate (yeast-form or hyphal) C. albicans orf19.4401 ORF YVH1 CAL0001708 PMID: 16000712|CGD_REF: CAL0114380 homozygous diploid, classical genetics null Not recorded vegetative growth: decreased rate C. albicans orf19.4401 ORF YVH1 CAL0001708 PMID: 16000712|CGD_REF: CAL0114380 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.4401 ORF YVH1 CAL0001708 PMID: 18708562|CGD_REF: CAL0119375 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.4401 ORF YVH1 CAL0001708 PMID: 16000712|CGD_REF: CAL0114380 homozygous diploid, classical genetics null CAI-4 hyphal growth: decreased solid and liquid media C. albicans orf19.4401 ORF YVH1 CAL0001708 PMID: 16000712|CGD_REF: CAL0114380 homozygous diploid, classical genetics null CAI-4 hyphal growth: decreased various liquid and solid media C. albicans orf19.4401 ORF YVH1 CAL0001708 PMID: 18708562|CGD_REF: CAL0119375 homozygous diploid, classical genetics null Not recorded virulence: decreased insect infection C. albicans orf19.4401 ORF YVH1 CAL0001708 PMID: 16000712|CGD_REF: CAL0114380 homozygous diploid, classical genetics null Not recorded virulence: decreased mouse intravenous infection C. albicans orf19.4401 ORF YVH1 CAL0001708 PMID: 16000712|CGD_REF: CAL0114380 heterozygous diploid, classical genetics overexpression Not recorded virulence: increased mouse intravenous infection C. albicans orf19.4403 ORF VPS11 CAL0001711 PMID: 16215175|CGD_REF: CAL0114836 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased vanadate(3-) C. albicans orf19.4403 ORF VPS11 CAL0001711 PMID: 12796286|CGD_REF: CAL0082026 homozygous diploid, classical genetics null BWP17 germ tube formation: delayed liquid serum-containing medium germ tube formation is also decreased C. albicans orf19.4403 ORF VPS11 CAL0001711 PMID: 16215175|CGD_REF: CAL0114836 homozygous diploid, classical genetics null BWP17 germ tube formation: delayed solid serum-containing medium C. albicans orf19.4403 ORF VPS11 CAL0001711 PMID: 16215175|CGD_REF: CAL0114836 homozygous diploid, classical genetics null BWP17 germ tube formation: delayed solid serum-containing medium C. albicans orf19.4403 ORF VPS11 CAL0001711 PMID: 16215175|CGD_REF: CAL0114836 homozygous diploid, classical genetics null Not recorded starvation resistance: decreased nitrogen starvation C. albicans orf19.4403 ORF VPS11 CAL0001711 PMID: 12796286|CGD_REF: CAL0082026 homozygous diploid, classical genetics null Not recorded heat sensitivity: increased C. albicans orf19.4403 ORF VPS11 CAL0001711 PMID: 12796286|CGD_REF: CAL0082026 homozygous diploid, classical genetics null Not recorded vacuolar morphology: abnormal cells lack vacuole C. albicans orf19.4403 ORF VPS11 CAL0001711 PMID: 12796286|CGD_REF: CAL0082026 homozygous diploid, classical genetics null Not recorded vegetative growth: decreased rate C. albicans orf19.4403 ORF VPS11 CAL0001711 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.4403 ORF VPS11 CAL0001711 PMID: 12796286|CGD_REF: CAL0082026 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.4403 ORF VPS11 CAL0001711 PMID: 12796286|CGD_REF: CAL0082026 homozygous diploid, classical genetics null Not recorded protein activity: decreased vacuolar hydrolase C. albicans orf19.4403 ORF VPS11 CAL0001711 PMID: 16215175|CGD_REF: CAL0114836 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased rapamycin C. albicans orf19.4403 ORF VPS11 CAL0001711 PMID: 16215175|CGD_REF: CAL0114836 homozygous diploid, classical genetics null BWP17 hyphal growth: decreased solid serum-containing medium few, morphologically abnormal, slow-growing hyphae C. albicans orf19.4403 ORF VPS11 CAL0001711 PMID: 12796286|CGD_REF: CAL0082026 homozygous diploid, classical genetics null BWP17 hyphal growth: absent liquid serum-containing media C. albicans orf19.4403 ORF VPS11 CAL0001711 PMID: 16215175|CGD_REF: CAL0114836 heterozygous diploid, classical genetics reduction of function vps11hr (lacking heptad repeat region) BWP17 oxidative stress resistance: decreased hydrogen peroxide slight increase C. albicans orf19.4403 ORF VPS11 CAL0001711 PMID: 16215175|CGD_REF: CAL0114836 heterozygous diploid, classical genetics reduction of function vps11hr (lacking heptad repeat region) BWP17 resistance to chemicals: decreased vanadate(3-) sensitivity is intermediate between that of the homozygous null mutant and wild type C. albicans orf19.4403 ORF VPS11 CAL0001711 PMID: 16215175|CGD_REF: CAL0114836 heterozygous diploid, classical genetics reduction of function vps11hr (lacking heptad repeat region) BWP17 resistance to chemicals: decreased rapamycin sensitivity is intermediate between that of the homozygous null mutant and wild type C. albicans orf19.4403 ORF VPS11 CAL0001711 PMID: 16215175|CGD_REF: CAL0114836 heterozygous diploid, classical genetics reduction of function vps11hr (lacking heptad repeat region) BWP17 chlamydospore formation: normal C. albicans orf19.4403 ORF VPS11 CAL0001711 PMID: 16215175|CGD_REF: CAL0114836 heterozygous diploid, classical genetics reduction of function vps11hr (lacking heptad repeat region) BWP17 filamentous growth: decreased solid M199 medium abnormal short and tufty filament morphology C. albicans orf19.4403 ORF VPS11 CAL0001711 PMID: 16215175|CGD_REF: CAL0114836 heterozygous diploid, classical genetics reduction of function vps11hr (lacking heptad repeat region) BWP17 germ tube formation: delayed solid serum-containing medium C. albicans orf19.4403 ORF VPS11 CAL0001711 PMID: 16215175|CGD_REF: CAL0114836 heterozygous diploid, classical genetics reduction of function vps11hr (lacking heptad repeat region) BWP17 heat sensitivity: normal C. albicans orf19.4403 ORF VPS11 CAL0001711 PMID: 16215175|CGD_REF: CAL0114836 heterozygous diploid, classical genetics reduction of function vps11hr (lacking heptad repeat region) BWP17 hyphal growth: abnormal solid serum-containing medium hyphae are slow-growing and short C. albicans orf19.4403 ORF VPS11 CAL0001711 PMID: 16215175|CGD_REF: CAL0114836 heterozygous diploid, classical genetics reduction of function vps11hr (lacking heptad repeat region) BWP17 osmotic stress resistance: normal C. albicans orf19.4403 ORF VPS11 CAL0001711 PMID: 16215175|CGD_REF: CAL0114836 heterozygous diploid, classical genetics reduction of function vps11hr (lacking heptad repeat region) BWP17 resistance to chemicals: decreased Hygromycin B sensitivity is intermediate between that of the homozygous null mutant and wild type C. albicans orf19.4403 ORF VPS11 CAL0001711 PMID: 16215175|CGD_REF: CAL0114836 heterozygous diploid, classical genetics reduction of function vps11hr (lacking heptad repeat region) BWP17 starvation resistance: decreased increased sensitivity to nitrogen starvation C. albicans orf19.4403 ORF VPS11 CAL0001711 PMID: 16215175|CGD_REF: CAL0114836 heterozygous diploid, classical genetics reduction of function vps11hr (lacking heptad repeat region) BWP17 vacuolar morphology: abnormal cells lack vacuole, show vacuolar fragmentation C. albicans orf19.4403 ORF VPS11 CAL0001711 PMID: 16215175|CGD_REF: CAL0114836 heterozygous diploid, classical genetics reduction of function vps11hr (lacking heptad repeat region) BWP17 vegetative growth: normal rate liquid YPD C. albicans orf19.4403 ORF VPS11 CAL0001711 PMID: 16215175|CGD_REF: CAL0114836 heterozygous diploid, classical genetics reduction of function vps11hr (lacking heptad repeat region) BWP17 viable C. albicans orf19.4403 ORF VPS11 CAL0001711 PMID: 16215175|CGD_REF: CAL0114836 heterozygous diploid, classical genetics reduction of function vps11hr (lacking heptad repeat region) BWP17 virulence: decreased decreased ability to kill murine macrophages; increased inviability upon macrophage engulfment in vitro model of infection C. albicans orf19.4403 ORF VPS11 CAL0001711 PMID: 16215175|CGD_REF: CAL0114836 homozygous diploid, classical genetics null Not recorded oxidative stress resistance: decreased hydrogen peroxide C. albicans orf19.4403 ORF VPS11 CAL0001711 PMID: 12796286|CGD_REF: CAL0082026 homozygous diploid, classical genetics null Not recorded cellular morphology: abnormal C. albicans orf19.4403 ORF VPS11 CAL0001711 PMID: 16215175|CGD_REF: CAL0114836 homozygous diploid, classical genetics null Not recorded chlamydospore formation: absent C. albicans orf19.4403 ORF VPS11 CAL0001711 PMID: 12796286|CGD_REF: CAL0082026 homozygous diploid, classical genetics null Not recorded osmotic stress resistance: decreased C. albicans orf19.4403 ORF VPS11 CAL0001711 PMID: 12796286|CGD_REF: CAL0082026 homozygous diploid, classical genetics null Not recorded protein secretion: decreased decreased secreted aspartyl protease activity C. albicans orf19.4403 ORF VPS11 CAL0001711 PMID: 12796286|CGD_REF: CAL0082026 homozygous diploid, classical genetics null Not recorded protein secretion: decreased decreased secreted lipase activity C. albicans orf19.4403 ORF VPS11 CAL0001711 PMID: 12796286|CGD_REF: CAL0082026 homozygous diploid, classical genetics null Not recorded metal resistance: decreased copper(2+) C. albicans orf19.4403 ORF VPS11 CAL0001711 PMID: 16215175|CGD_REF: CAL0114836 homozygous diploid, classical genetics null BWP17 filamentous growth: absent solid M199 medium C. albicans orf19.4403 ORF VPS11 CAL0001711 PMID: 16215175|CGD_REF: CAL0114836 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased Hygromycin B C. albicans orf19.4403 ORF VPS11 CAL0001711 PMID: 21407800|CGD_REF: CAL0141800 homozygous diploid, classical genetics null BWP17 interaction with host/environment: abnormal significantly reduces adhesion, invasion, and damage to epithelial cells ex vivo model of infection C. albicans orf19.4403 ORF VPS11 CAL0001711 PMID: 16215175|CGD_REF: CAL0114836 homozygous diploid, classical genetics null Not recorded virulence: decreased murine macrophage culture decreased survival in the presence of macrophages; decreased ability to kill macrophages in vitro model of infection C. albicans orf19.4405 ORF PPS1 CAL0001715 PMID: 18708562|CGD_REF: CAL0119375 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.4405 ORF PPS1 CAL0001715 PMID: 18708562|CGD_REF: CAL0119375 homozygous diploid, classical genetics null Not recorded virulence: decreased insect infection C. albicans orf19.4406 ORF NIF3 CAL0001717 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.4407 ORF CAL0001719 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.4407 ORF CAL0001719 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.4407 ORF CAL0001719 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.4407 ORF CAL0001719 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.4409 ORF CAL0001722 PMID: 14663094|CGD_REF: CAL0080633 homozygous diploid, systematic mutation set (homozygous insertion mutants generated with URA3-ARG4-URA3 (UAU1) cassette) null BWP17 viable C. albicans orf19.441 ORF RPT1 CAL0005689 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.4410 ORF ALG1 CAL0001745 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.4410 ORF ALG1 CAL0001745 PMID: 12524333|CGD_REF: CAL0080691 homozygous diploid, systematic mutation set (homozygous insertion mutants generated with URA3-ARG4-URA3 (UAU1) cassette) null BWP17 inviable homozygous null mutant strain could not be recovered, suggesting that the gene is essential under the selection conditions C. albicans orf19.4411 ORF HOS1 CAL0001747 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.4411 ORF HOS1 CAL0001747 PMID: 19555456|CGD_REF: CAL0123821 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.4412 ORF CAL0001748 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.4412 ORF CAL0001748 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.4412 ORF CAL0001748 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.4412 ORF CAL0001748 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.4412 ORF CAL0001748 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 invasive growth: decreased solid SLAD media C. albicans orf19.4412 ORF CAL0001748 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.4413 ORF CMD1 CAL0001750 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.4413 ORF CMD1 CAL0001750 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, competitive growth (haploinsufficient phenotype assay, barcode deletion set) null SC5314 resistance to chemicals: decreased cytochalasin D C. albicans orf19.4413 ORF CMD1 CAL0001750 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, competitive growth (haploinsufficient phenotype assay, barcode deletion set) null SC5314 resistance to chemicals: decreased tunicamycin C. albicans orf19.4413 ORF CMD1 CAL0001750 PMID: 19115836|CGD_REF: CAL0122036 heterozygous diploid, competitive growth (haploinsufficient phenotype assay, barcode deletion set) null SC5314 resistance to chemicals: decreased virgineone C. albicans orf19.4413 ORF CMD1 CAL0001750 PMID: 20494978|CGD_REF: CAL0125636 heterozygous diploid, classical genetics null BWP17 resistance to chemicals: decreased clotrimazole (75 uM) growth in liquid culture confirmation of mutant phenotypes for heterozygous transposon insertion strains showing sensitivity in a large-scale assay C. albicans orf19.4415 ORF MED3 CAL0001754 PMID: 23873866|CGD_REF: CAL0000172574 homozygous diploid, classical genetics null SN152 viable C. albicans orf19.4415 ORF MED3 CAL0001754 PMID: 23873866|CGD_REF: CAL0000172574 homozygous diploid, classical genetics null SN152 mating efficiency: decreased C. albicans orf19.4415 ORF MED3 CAL0001754 PMID: 23873866|CGD_REF: CAL0000172574 homozygous diploid, classical genetics null SN152 phenotypic switching: abnormal C. albicans orf19.4416 ORF VPS13 CAL0001755 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.4418 ORF FMT1 CAL0001758 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.4424 ORF PHO100 CAL0001782 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.4424 ORF PHO100 CAL0001782 PMID: 19151328|CGD_REF: CAL0122238 homozygous diploid, classical genetics null CAI-4 viable URA-blaster technique, with URA3 integrated at RPS1 C. albicans orf19.4424 ORF PHO100 CAL0001782 PMID: 19151328|CGD_REF: CAL0122238 heterozygous diploid, classical genetics null Not recorded viable C. albicans orf19.4424 ORF PHO100 CAL0001782 PMID: 19151328|CGD_REF: CAL0122238 homozygous diploid, classical genetics null Not recorded protein secretion: increased increased secreted acid phosphatase activity C. albicans orf19.4424 ORF PHO100 CAL0001782 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.4424 ORF PHO100 CAL0001782 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.4424 ORF PHO100 CAL0001782 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.4424 ORF PHO100 CAL0001782 PMID: 19151328|CGD_REF: CAL0122238 homozygous diploid, classical genetics null Not recorded virulence: decreased mouse intravenous infection C. albicans orf19.4424 ORF PHO100 CAL0001782 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.4427 ORF SKP1 CAL0001786 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.4428 ORF CAL0001787 PMID: 14663094|CGD_REF: CAL0080633 homozygous diploid, systematic mutation set (homozygous insertion mutants generated with URA3-ARG4-URA3 (UAU1) cassette) null BWP17 viable C. albicans orf19.443 ORF CAL0005692 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.4432 ORF KSP1 CAL0001809 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.4432 ORF KSP1 CAL0001809 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, competitive growth (haploinsufficient phenotype assay, barcode deletion set) null SC5314 resistance to chemicals: decreased amphotericin B C. albicans orf19.4432 ORF KSP1 CAL0001809 PMID: 20494978|CGD_REF: CAL0125636 heterozygous diploid, classical genetics null BWP17 resistance to chemicals: decreased clotrimazole (75 uM) growth in liquid culture confirmation of mutant phenotypes for heterozygous transposon insertion strains showing sensitivity in a large-scale assay C. albicans orf19.4433 ORF CPH1 CAL0001810 PMID: 18467082|CGD_REF: CAL0119001 homozygous diploid, classical genetics null Not recorded germ tube formation: delayed C. albicans orf19.4433 ORF CPH1 CAL0001810 PMID: 19188358|CGD_REF: CAL0122313 homozygous diploid, classical genetics null Not recorded germ tube formation: normal arginine- or urea-containing media or 5% carbon dioxide C. albicans orf19.4433 ORF CPH1 CAL0001810 PMID: 7992058|CGD_REF: CAL0081052 homozygous diploid, classical genetics null CAI-4 germ tube formation: normal liquid serum-containing medium C. albicans orf19.4433 ORF CPH1 CAL0001810 PMID: 16467475|CGD_REF: CAL0115509 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased Calcofluor White C. albicans orf19.4433 ORF CPH1 CAL0001810 PMID: 15964282|CGD_REF: CAL0114274 homozygous diploid, systematic mutation set (split-marker transposon insertion strategy to disrupt both alleles) null BWP17 viable C. albicans orf19.4433 ORF CPH1 CAL0001810 PMID: 7992058|CGD_REF: CAL0081052 homozygous diploid, classical genetics null Not recorded viable wild-type growth rate C. albicans orf19.4433 ORF CPH1 CAL0001810 PMID: 11533231|CGD_REF: CAL0080743 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.4433 ORF CPH1 CAL0001810 PMID: 12453219|CGD_REF: CAL0080981 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.4433 ORF CPH1 CAL0001810 PMID: 12453219|CGD_REF: CAL0080981 heterozygous diploid, classical genetics overexpression Not recorded viable C. albicans orf19.4433 ORF CPH1 CAL0001810 PMID: 19463063|CGD_REF: CAL0123630 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.4433 ORF CPH1 CAL0001810 PMID: 9596738|CGD_REF: CAL0080971 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.4433 ORF CPH1 CAL0001810 PMID: 9596738|CGD_REF: CAL0080971 homozygous diploid, classical genetics null CAI-4 hyphal growth: abnormal solid SLAD medium decreased and aberrant hyphal growth C. albicans orf19.4433 ORF CPH1 CAL0001810 PMID: 11533231|CGD_REF: CAL0080743 homozygous diploid, classical genetics null Not recorded hyphal growth: absent solid SSA medium C. albicans orf19.4433 ORF CPH1 CAL0001810 PMID: 11595734|CGD_REF: CAL0081060 homozygous diploid, classical genetics null Not recorded hyphal growth: normal YPD plus serum medium at 37 deg C C. albicans orf19.4433 ORF CPH1 CAL0001810 PMID: 7992058|CGD_REF: CAL0081052 homozygous diploid, classical genetics null CAI-4 hyphal growth: normal liquid Lee's medium C. albicans orf19.4433 ORF CPH1 CAL0001810 PMID: 7992058|CGD_REF: CAL0081052 homozygous diploid, classical genetics null CAI-4 hyphal growth: decreased solid Spider or Lee's plus mannitol media C. albicans orf19.4433 ORF CPH1 CAL0001810 PMID: 10564506|CGD_REF: CAL0081058 homozygous diploid, classical genetics null cph1::hisG/cph1::hisG CAI-4 filamentous growth: normal C. albicans orf19.4433 ORF CPH1 CAL0001810 PMID: 15964282|CGD_REF: CAL0114274 homozygous diploid, systematic mutation set (split-marker transposon insertion strategy to disrupt both alleles) null BWP17 biofilm formation: normal C. albicans orf19.4433 ORF CPH1 CAL0001810 PMID: 16980403|CGD_REF: CAL0116783 homozygous diploid, classical genetics null Not recorded chemical compound accumulation: normal tyrosol C. albicans orf19.4433 ORF CPH1 CAL0001810 PMID: 12453219|CGD_REF: CAL0080981 heterozygous diploid, classical genetics overexpression Not recorded mating efficiency: increased C. albicans orf19.4433 ORF CPH1 CAL0001810 PMID: 12453219|CGD_REF: CAL0080981 homozygous diploid, classical genetics null Not recorded mating response: absent C. albicans orf19.4433 ORF CPH1 CAL0001810 PMID: 12453220|CGD_REF: CAL0080738 homozygous diploid, classical genetics null Not recorded mating response: absent C. albicans orf19.4433 ORF CPH1 CAL0001810 PMID: 18162580|CGD_REF: CAL0118948 homozygous diploid, classical genetics null Not recorded phenotypic switching: normal C. albicans orf19.4433 ORF CPH1 CAL0001810 PMID: 16039996|CGD_REF: CAL0114588 homozygous diploid, classical genetics null Not recorded pseudohyphal growth: decreased defect in pseudohyphal growth after prolonged (16 h) incubation with macrophages, at which point there is significant macrophage lysis C. albicans orf19.4433 ORF CPH1 CAL0001810 PMID: 11595734|CGD_REF: CAL0081060 heterozygous diploid, classical genetics overexpression Not recorded pseudohyphal growth: abnormal pseudohyphal growth observed under conditions that induce yeast-form growth of wild type C. albicans orf19.4433 ORF CPH1 CAL0001810 PMID: 16467475|CGD_REF: CAL0115509 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased Congo Red C. albicans orf19.4433 ORF CPH1 CAL0001810 PMID: 11595734|CGD_REF: CAL0081060 homozygous diploid, classical genetics null Not recorded filamentous growth: decreased liquid SS medium or succinate carbon source carbon-source dependent defect in filamentation C. albicans orf19.4433 ORF CPH1 CAL0001810 PMID: 16980403|CGD_REF: CAL0116783 homozygous diploid, classical genetics null Not recorded filamentous growth: decreased in biofilms C. albicans orf19.4433 ORF CPH1 CAL0001810 PMID: 18467082|CGD_REF: CAL0119001 heterozygous diploid, classical genetics overexpression Not recorded filamentous growth: increased C. albicans orf19.4433 ORF CPH1 CAL0001810 PMID: 15813733|CGD_REF: CAL0104041 homozygous diploid, classical genetics null CAI-4 resistance to killing by host cells: decreased decreased viability in the presence of human blood components C. albicans orf19.4433 ORF CPH1 CAL0001810 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.4433 ORF CPH1 CAL0001810 PMID: 9596738|CGD_REF: CAL0080971 unknown ploidy, classical genetics overexpression CAI-4 viable C. albicans orf19.4433 ORF CPH1 CAL0001810 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.4433 ORF CPH1 CAL0001810 PMID: 22276126|CGD_REF: CAL0000143926 aneuploid, classical genetics overexpression Other C. albicans filamentous growth: increased C. albicans orf19.4433 ORF CPH1 CAL0001810 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.4433 ORF CPH1 CAL0001810 PMID: 16980403|CGD_REF: CAL0116783 homozygous diploid, classical genetics null SC5314 biofilm formation: abnormal defect in filamentous growth in biofilm, and yeast-form biofilm cells do not respond to tyrosol C. albicans orf19.4433 ORF CPH1 CAL0001810 PMID: 19463063|CGD_REF: CAL0123630 homozygous diploid, systematic mutation set (split-marker transposon insertion strategy to disrupt both alleles) null BWP17 virulence: normal Toll mutant D. melanogaster invasive infection insect infection C. albicans orf19.4433 ORF CPH1 CAL0001810 PMID: 16518764|CGD_REF: CAL0115737 homozygous diploid, classical genetics null Not recorded virulence: decreased insect infection C. albicans orf19.4433 ORF CPH1 CAL0001810 PMID: 23637598|CGD_REF: CAL0000172002 homozygous diploid, classical genetics null a/a cph1/cph1 (opaque cells) P37005 mating projection morphology: abnormal 37 degrees C in Spider medium with gentle shaking formation of mating projections are absent C. albicans orf19.4433 ORF CPH1 CAL0001810 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.4433 ORF CPH1 CAL0001810 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 invasive growth: decreased solid SLAD media C. albicans orf19.4435 ORF CAL0001812 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.4436 ORF GPX3 CAL0001814 PMID: 23706023|CGD_REF: CAL0000172371 homozygous diploid, classical genetics null Other C. albicans viable C. albicans orf19.4436 ORF GPX3 CAL0001814 PMID: 23706023|CGD_REF: CAL0000172371 homozygous diploid, classical genetics null Other C. albicans oxidative stress resistance: decreased hydrogen peroxide C. albicans orf19.4436 ORF GPX3 CAL0001814 PMID: 23706023|CGD_REF: CAL0000172371 homozygous diploid, classical genetics null Other C. albicans virulence: normal mouse intravenous infection C. albicans orf19.4436 ORF GPX3 CAL0001814 PMID: 23706023|CGD_REF: CAL0000172371 homozygous diploid, classical genetics null Other C. albicans virulence: decreased insect infection (Galleria mellonella survival model) C. albicans orf19.444 ORF CAL0005693 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.4440 ORF SEC34 CAL0001837 PMID: 14663094|CGD_REF: CAL0080633 homozygous diploid, systematic mutation set (homozygous insertion mutants generated with URA3-ARG4-URA3 (UAU1) cassette) null BWP17 viable C. albicans orf19.4441 ORF CAL0001839 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.4443 ORF YPD1 CAL0001843 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.4443 ORF YPD1 CAL0001843 PMID: 24489039|CGD_REF: CAL0000173768 homozygous diploid, classical genetics null SN152 viable C. albicans orf19.4443 ORF YPD1 CAL0001843 PMID: 24489039|CGD_REF: CAL0000173768 homozygous diploid, classical genetics null SN152 vegetative growth: decreased rate C. albicans orf19.4443 ORF YPD1 CAL0001843 PMID: 24489039|CGD_REF: CAL0000173768 homozygous diploid, classical genetics null SN152 flocculation: increased C. albicans orf19.4443 ORF YPD1 CAL0001843 PMID: 24489039|CGD_REF: CAL0000173768 homozygous diploid, classical genetics null SN152 filamentous growth: increased C. albicans orf19.4443 ORF YPD1 CAL0001843 PMID: 24489039|CGD_REF: CAL0000173768 homozygous diploid, classical genetics null SN152 resistance to chemicals: decreased sodium dodecyl sulfate (0.025%) C. albicans orf19.4444 ORF PHO15 CAL0001845 PMID: 19555456|CGD_REF: CAL0123821 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.4444 ORF PHO15 CAL0001845 PMID: 19555456|CGD_REF: CAL0123821 homozygous diploid, classical genetics null Not recorded phenotypic switching: increased MTLa/MTLa background opaque-to-white switching C. albicans orf19.4444 ORF PHO15 CAL0001845 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.4444 ORF PHO15 CAL0001845 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: abnormal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.4444 ORF PHO15 CAL0001845 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.4444 ORF PHO15 CAL0001845 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.4445 ORF CAL0001847 PMID: 20023067|CGD_REF: CAL0124775 homozygous diploid, classical genetics null SC5314 viable C. albicans orf19.4445 ORF CAL0001847 PMID: 20023067|CGD_REF: CAL0124775 heterozygous diploid, classical genetics null SC5314 viable C. albicans orf19.4445 ORF CAL0001847 PMID: 20023067|CGD_REF: CAL0124775 homozygous diploid, classical genetics null SC5314 filamentous growth: normal 10% fetal calf serum C. albicans orf19.4445 ORF CAL0001847 PMID: 20023067|CGD_REF: CAL0124775 homozygous diploid, classical genetics null SC5314 invasive growth: normal growth into agar substrate C. albicans orf19.4445 ORF CAL0001847 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.4445 ORF CAL0001847 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.4445 ORF CAL0001847 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.4445 ORF CAL0001847 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.4447 ORF YMC1 CAL0001851 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.4448 ORF SOG2 CAL0001853 PMID: 18843050|CGD_REF: CAL0120345 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased Calcofluor White C. albicans orf19.4448 ORF SOG2 CAL0001853 PMID: 18843050|CGD_REF: CAL0120345 heterozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased itraconazole sensitivity is intermediate between that of the homozygous null mutant and wild type C. albicans orf19.4448 ORF SOG2 CAL0001853 PMID: 18843050|CGD_REF: CAL0120345 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased itraconazole C. albicans orf19.4448 ORF SOG2 CAL0001853 PMID: 18843050|CGD_REF: CAL0120345 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased sodium dodecyl sulfate C. albicans orf19.4448 ORF SOG2 CAL0001853 PMID: 18843050|CGD_REF: CAL0120345 homozygous diploid, classical genetics null Not recorded vegetative growth: decreased rate C. albicans orf19.4448 ORF SOG2 CAL0001853 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.4448 ORF SOG2 CAL0001853 PMID: 18843050|CGD_REF: CAL0120345 heterozygous diploid, classical genetics null Not recorded viable URA3-blaster technique C. albicans orf19.4448 ORF SOG2 CAL0001853 PMID: 18843050|CGD_REF: CAL0120345 homozygous diploid, classical genetics null Not recorded viable URA3-blaster technique C. albicans orf19.4448 ORF SOG2 CAL0001853 PMID: 18843050|CGD_REF: CAL0120345 homozygous diploid, classical genetics null CAI-4 hyphal growth: decreased solid and liquid media C. albicans orf19.4448 ORF SOG2 CAL0001853 PMID: 18843050|CGD_REF: CAL0120345 homozygous diploid, classical genetics null Not recorded cell cycle progression: abnormal cells are multinucleate C. albicans orf19.4448 ORF SOG2 CAL0001853 PMID: 18843050|CGD_REF: CAL0120345 homozygous diploid, classical genetics null Not recorded cell shape: abnormal cells are round and enlarged C. albicans orf19.4448 ORF SOG2 CAL0001853 PMID: 18843050|CGD_REF: CAL0120345 homozygous diploid, classical genetics null Not recorded hypoosmotic stress resistance: decreased cells lyse in liquid YPD C. albicans orf19.4448 ORF SOG2 CAL0001853 PMID: 18843050|CGD_REF: CAL0120345 homozygous diploid, classical genetics null Not recorded cell size: increased cells are round, large, and heterogeneous in size C. albicans orf19.4448 ORF SOG2 CAL0001853 PMID: 18843050|CGD_REF: CAL0120345 homozygous diploid, classical genetics null Not recorded cytokinesis: absent C. albicans orf19.4448 ORF SOG2 CAL0001853 PMID: 18843050|CGD_REF: CAL0120345 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased Congo Red C. albicans orf19.4448 ORF SOG2 CAL0001853 PMID: 18843050|CGD_REF: CAL0120345 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased Hygromycin B C. albicans orf19.4448 ORF SOG2 CAL0001853 PMID: 18843050|CGD_REF: CAL0120345 heterozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased fluconazole sensitivity is intermediate between that of the homozygous null mutant and wild type C. albicans orf19.4448 ORF SOG2 CAL0001853 PMID: 18843050|CGD_REF: CAL0120345 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased fluconazole C. albicans orf19.4448 ORF SOG2 CAL0001853 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 invasive growth: decreased solid SLAD media C. albicans orf19.4451 ORF RIA1 CAL0001869 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.4451 ORF RIA1 CAL0001869 PMID: 14507372|CGD_REF: CAL0088818 heterozygous diploid, large-scale survey (large-scale identification of essential genes by gene replacement and conditional expression (GRACE) method) repressible CAI-4 viable one allele is deleted and the other is placed under repressible Tet promoter C. albicans orf19.4457 ORF BNI4 CAL0001878 PMID: 15470104|CGD_REF: CAL0082131 homozygous diploid, classical genetics null Not recorded resistance to chemicals: increased Calcofluor White C. albicans orf19.4457 ORF BNI4 CAL0001878 PMID: 14663094|CGD_REF: CAL0080633 homozygous diploid, systematic mutation set (homozygous insertion mutants generated with URA3-ARG4-URA3 (UAU1) cassette) null BWP17 viable C. albicans orf19.4457 ORF BNI4 CAL0001878 PMID: 15470104|CGD_REF: CAL0082131 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.4457 ORF BNI4 CAL0001878 PMID: 15470104|CGD_REF: CAL0082131 homozygous diploid, classical genetics null CAI-4 hyphal growth: normal liquid Lee's medium pH 6.5 at 37 deg C C. albicans orf19.4457 ORF BNI4 CAL0001878 PMID: 15470104|CGD_REF: CAL0082131 homozygous diploid, classical genetics null CAI-4 hyphal growth: decreased solid serum-containing medium C. albicans orf19.4457 ORF BNI4 CAL0001878 PMID: 15470104|CGD_REF: CAL0082131 homozygous diploid, classical genetics null Not recorded cell shape: abnormal cells are lemon shaped and have abnormal distribution of bud scars C. albicans orf19.4457 ORF BNI4 CAL0001878 PMID: 16002645|CGD_REF: CAL0114398 homozygous diploid, classical genetics null Not recorded cell shape: abnormal protrusions are observed at sites of cell division C. albicans orf19.4457 ORF BNI4 CAL0001878 PMID: 15470104|CGD_REF: CAL0082131 homozygous diploid, classical genetics null Not recorded chitin deposition: decreased decreased cell wall chitin C. albicans orf19.4457 ORF BNI4 CAL0001878 PMID: 16002645|CGD_REF: CAL0114398 homozygous diploid, classical genetics null Not recorded chlamydospore formation: normal C. albicans orf19.4457 ORF BNI4 CAL0001878 PMID: 12773383|CGD_REF: CAL0087974 heterozygous diploid, classical genetics (haploinsufficient phenotype assay) unspecified CAI-4 filamentous growth: increased solid YEPD plus serum transposon insertion proximal to, but not within, the ORF C. albicans orf19.4459 ORF CAL0001881 PMID: 12773383|CGD_REF: CAL0087974 heterozygous diploid, classical genetics (haploinsufficient phenotype assay) unspecified CAI-4 filamentous growth: increased solid YEPD plus serum transposon insertion proximal to, but not within, the ORF C. albicans orf19.4459 ORF CAL0001881 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.4459 ORF CAL0001881 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: abnormal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.4459 ORF CAL0001881 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.4459 ORF CAL0001881 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.4461 ORF CAL0001906 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.4466 ORF CAL0001917 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.4466 ORF CAL0001917 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: abnormal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.4466 ORF CAL0001917 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.4466 ORF CAL0001917 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.4468 ORF CAL0001921 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.4471 ORF CAL0001948 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.4471 ORF CAL0001948 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: increased growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.4471 ORF CAL0001948 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: abnormal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.4471 ORF CAL0001948 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.4471 ORF CAL0001948 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.4473 ORF SPC19 CAL0001953 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.4473 ORF SPC19 CAL0001953 PMID: 21549601|CGD_REF: CAL0142005 heterozygous diploid, classical genetics repressible BWP17 inviable repressible conditions (with tetracycline) Gene replacement and conditional expression (GRACE) C. albicans orf19.4473 ORF SPC19 CAL0001953 PMID: 21571923|CGD_REF: CAL0142042 homozygous diploid, classical genetics repressible spc19::HIS1/MET3(p)-SPC19 Other C. albicans cell cycle progression: arrested repressing conditions mutant accumulates large budded cells after 4h of growth under nonpermissive conditions, prolonged incubation leads to a transition to an elongated (pseudohyphal-like) bud C. albicans orf19.4473 ORF SPC19 CAL0001953 PMID: 21571923|CGD_REF: CAL0142042 homozygous diploid, classical genetics repressible spc19::HIS1/MET3(p)-SPC19 Other C. albicans inviable repressing conditions C. albicans orf19.4473 ORF SPC19 CAL0001953 PMID: 21571923|CGD_REF: CAL0142042 homozygous diploid, classical genetics repressible spc19::HIS1/MET3(p)-SPC19 Other C. albicans chromosome segregation: abnormal repressing conditions C. albicans orf19.4474 ORF CAL0001956 PMID: 14663094|CGD_REF: CAL0080633 homozygous diploid, systematic mutation set (homozygous insertion mutants generated with URA3-ARG4-URA3 (UAU1) cassette) null BWP17 viable C. albicans orf19.4474 ORF CAL0001956 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.4474 ORF CAL0001956 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.4474 ORF CAL0001956 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.4474 ORF CAL0001956 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.4475 ORF KTR4 CAL0001958 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.4475 ORF KTR4 CAL0001958 PMID: 20164191|CGD_REF: CAL0124956 homozygous diploid, classical genetics null ktr4::hisG/ktr4::hisG CAI-4 viable C. albicans orf19.4475 ORF KTR4 CAL0001958 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.4475 ORF KTR4 CAL0001958 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.4475 ORF KTR4 CAL0001958 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.4475 ORF KTR4 CAL0001958 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.4476 ORF CAL0001960 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.4477 ORF CSH1 CAL0001962 PMID: 11371521|CGD_REF: CAL0081084 homozygous diploid, classical genetics null Not recorded germ tube formation: normal C. albicans orf19.4477 ORF CSH1 CAL0001962 PMID: 11371521|CGD_REF: CAL0081084 homozygous diploid, classical genetics null Not recorded viable wild-type growth rate C. albicans orf19.4477 ORF CSH1 CAL0001962 PMID: 11371521|CGD_REF: CAL0081084 homozygous diploid, classical genetics null Not recorded adhesion: decreased adhesion to fibronectin at 23 deg C C. albicans orf19.4477 ORF CSH1 CAL0001962 PMID: 15766793|CGD_REF: CAL0082249 homozygous diploid, classical genetics null Not recorded adhesion: normal adhesion to fibronectin C. albicans orf19.4477 ORF CSH1 CAL0001962 PMID: 19529758|CGD_REF: CAL0123764 heterozygous diploid, classical genetics overexpression BWP17 biofilm formation: abnormal C. albicans orf19.4477 ORF CSH1 CAL0001962 PMID: 11371521|CGD_REF: CAL0081084 homozygous diploid, classical genetics null Not recorded cell wall morphology: abnormal decreased cell surface hydrophobicity C. albicans orf19.4477 ORF CSH1 CAL0001962 PMID: 19798425|CGD_REF: CAL0124304 homozygous diploid, classical genetics null Other C. albicans biofilm formation: abnormal C. albicans orf19.4477 ORF CSH1 CAL0001962 PMID: 15766793|CGD_REF: CAL0082249 heterozygous diploid, classical genetics null Not recorded virulence: decreased virulence is intermediate between that of the homozygous null mutant and wild type mouse intravenous infection C. albicans orf19.4477 ORF CSH1 CAL0001962 PMID: 15766793|CGD_REF: CAL0082249 homozygous diploid, classical genetics null Not recorded virulence: decreased mouse intravenous infection C. albicans orf19.4477 ORF CSH1 CAL0001962 PMID: 15766793|CGD_REF: CAL0082249 heterozygous diploid, classical genetics null Not recorded virulence: decreased virulence is intermediate between that of the homozygous null mutant and wild type mouse vaginal infection C. albicans orf19.4477 ORF CSH1 CAL0001962 PMID: 15766793|CGD_REF: CAL0082249 homozygous diploid, classical genetics null Not recorded virulence: decreased mouse vaginal infection C. albicans orf19.4478 ORF CAL0001963 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.4479 ORF CAL0001965 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.4479 ORF CAL0001965 PMID: 21135205|CGD_REF: CAL0139967 heterozygous diploid, large-scale survey (large-scale identification of genes essential for virulence in mouse) repressible CAI-4 virulence: absent mouse intravenous infection C. albicans orf19.448 ORF CUE5 CAL0005703 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.4481 ORF MFALPHA CAL0001991 PMID: 14585977|CGD_REF: CAL0081534 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.4481 ORF MFALPHA CAL0001991 PMID: 14665468|CGD_REF: CAL0081469 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.4481 ORF MFALPHA CAL0001991 PMID: 14585977|CGD_REF: CAL0081534 homozygous diploid, classical genetics null Not recorded mating response: abnormal mutant MTLalpha cells do not mate C. albicans orf19.4481 ORF MFALPHA CAL0001991 PMID: 14665468|CGD_REF: CAL0081469 homozygous diploid, classical genetics null Not recorded mating response: abnormal mutant MTLalpha cells do not mate, but mating of MTLa cells is unaffected C. albicans orf19.4481 ORF MFALPHA CAL0001991 PMID: 21498642|CGD_REF: CAL0141911 homozygous diploid, classical genetics null P37005 biofilm formation: decreased defect in white MTLa/MTLa cell biofilm formation C. albicans orf19.4488 ORF CAL0002007 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient SLAD medium C. albicans orf19.449 ORF CAL0005709 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.449 ORF CAL0005709 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: decreased growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.449 ORF CAL0005709 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.449 ORF CAL0005709 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.449 ORF CAL0005709 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.4490 ORF RPL17B CAL0002028 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, competitive growth (haploinsufficient phenotype assay, barcode deletion set) null SC5314 resistance to chemicals: decreased 5-fluorouracil C. albicans orf19.4490 ORF RPL17B CAL0002028 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, competitive growth (haploinsufficient phenotype assay, barcode deletion set) null SC5314 resistance to chemicals: decreased tubercidin C. albicans orf19.4490 ORF RPL17B CAL0002028 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.4491 ORF ERG20 CAL0002030 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.4491 ORF ERG20 CAL0002030 PMID: 12524333|CGD_REF: CAL0080691 homozygous diploid, systematic mutation set (homozygous insertion mutants generated with URA3-ARG4-URA3 (UAU1) cassette) null BWP17 inviable homozygous null mutant strain could not be recovered, suggesting that the gene is essential under the selection conditions C. albicans orf19.4491 ORF ERG20 CAL0002030 PMID: 21135205|CGD_REF: CAL0139967 heterozygous diploid, large-scale survey (large-scale identification of genes essential for virulence in mouse) repressible CAI-4 virulence: absent mouse intravenous infection C. albicans orf19.4492 ORF CAL0002033 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.4492 ORF CAL0002033 PMID: 21135205|CGD_REF: CAL0139967 heterozygous diploid, large-scale survey (large-scale identification of genes essential for virulence in mouse) repressible CAI-4 virulence: absent mouse intravenous infection C. albicans orf19.4494 ORF KTR2 CAL0002037 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.4494 ORF KTR2 CAL0002037 PMID: 20164191|CGD_REF: CAL0124956 homozygous diploid, classical genetics null ktr2::hisG/ktr2::hisG CAI-4 viable C. albicans orf19.4495 ORF NDH51 CAL0002040 PMID: 12081465|CGD_REF: CAL0081582 homozygous diploid, classical genetics null Not recorded respiratory growth: absent unable to utilize nonfermentable carbon sources ethanol or acetate C. albicans orf19.4495 ORF NDH51 CAL0002040 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.4495 ORF NDH51 CAL0002040 PMID: 12081465|CGD_REF: CAL0081582 heterozygous diploid, classical genetics null Not recorded viable C. albicans orf19.4495 ORF NDH51 CAL0002040 PMID: 12081465|CGD_REF: CAL0081582 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.4495 ORF NDH51 CAL0002040 PMID: 12081465|CGD_REF: CAL0081582 homozygous diploid, classical genetics null BWP17 filamentous growth: absent low glucose media no germ tubes, pseudohyphae, or hyphae observed C. albicans orf19.4495 ORF NDH51 CAL0002040 PMID: 19707174|CGD_REF: CAL0124230 homozygous diploid, classical genetics null BWP17 biofilm formation: decreased assayed by safranin staining of exopolysaccharide matrix C. albicans orf19.4496 ORF CAL0002043 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.4496 ORF CAL0002043 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.4496 ORF CAL0002043 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.4496 ORF CAL0002043 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.4496 ORF CAL0002043 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.4497 ORF MED8 CAL0002045 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.4497 ORF MED8 CAL0002045 PMID: 14663094|CGD_REF: CAL0080633 homozygous diploid, systematic mutation set (homozygous insertion mutants generated with URA3-ARG4-URA3 (UAU1) cassette) null BWP17 viable C. albicans orf19.4499 ORF RIM2 CAL0002049 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.4502 ORF CAL0002614 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.4503 ORF CAL0002616 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.4506 ORF LYS22 CAL0002622 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.4506 ORF LYS22 CAL0002622 PMID: 20571912|CGD_REF: CAL0125848 homozygous diploid, classical genetics null SC5314 viable C. albicans orf19.4506 ORF LYS22 CAL0002622 PMID: 20571912|CGD_REF: CAL0125848 homozygous diploid, classical genetics null SC5314 virulence: normal mouse intravenous infection C. albicans orf19.4513 ORF CAL0002652 PMID: 14663094|CGD_REF: CAL0080633 homozygous diploid, systematic mutation set (homozygous insertion mutants generated with URA3-ARG4-URA3 (UAU1) cassette) null BWP17 viable C. albicans orf19.4516 ORF CAL0002657 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.4517 ORF CAL0002659 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient YPD medium C. albicans orf19.4517 ORF CAL0002659 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient SC medium C. albicans orf19.4517 ORF CAL0002659 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient YNB medium C. albicans orf19.4518 ORF CAL0002661 PMID: 14663094|CGD_REF: CAL0080633 homozygous diploid, systematic mutation set (homozygous insertion mutants generated with URA3-ARG4-URA3 (UAU1) cassette) null BWP17 viable C. albicans orf19.4519 ORF SUV3 CAL0002663 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.4519 ORF SUV3 CAL0002663 PMID: 14663094|CGD_REF: CAL0080633 homozygous diploid, systematic mutation set (homozygous insertion mutants generated with URA3-ARG4-URA3 (UAU1) cassette) null BWP17 viable C. albicans orf19.4519 ORF SUV3 CAL0002663 PMID: 14663094|CGD_REF: CAL0080633 homozygous diploid, systematic mutation set (homozygous insertion mutants generated with URA3-ARG4-URA3 (UAU1) cassette) null BWP17 hyphal growth: absent embedded in solid medium C. albicans orf19.4519 ORF SUV3 CAL0002663 PMID: 14663094|CGD_REF: CAL0080633 homozygous diploid, systematic mutation set (homozygous insertion mutants generated with URA3-ARG4-URA3 (UAU1) cassette) null BWP17 chlamydospore formation: absent C. albicans orf19.4519 ORF SUV3 CAL0002663 PMID: 15813744|CGD_REF: CAL0104042 homozygous diploid, classical genetics null Not recorded resistance to chemicals: increased fluconazole C. albicans orf19.4519 ORF SUV3 CAL0002663 PMID: 16087754|CGD_REF: CAL0114512 homozygous diploid, classical genetics null BWP17 biofilm formation: decreased C. albicans orf19.4519 ORF SUV3 CAL0002663 PMID: 23856128|CGD_REF: CAL0000172540 homozygous diploid, classical genetics null BWP17 resistance to chemicals: decreased propolis C. albicans orf19.4519 ORF SUV3 CAL0002663 PMID: 17241762|CGD_REF: CAL0117323 homozygous diploid, classical genetics null Not recorded virulence: decreased mouse corneal infection C. albicans orf19.4519 ORF SUV3 CAL0002663 PMID: 16087754|CGD_REF: CAL0114512 homozygous diploid, classical genetics null suv3::Tn7-UAU1/suv3::Tn7-URA3 BWP17 biofilm formation: abnormal 60 h at 37 deg C in Spider medium or 60 h at 37 deg C in SD medium plus 50 mM glucose on silicone squares blocked at an early step of biofilm formation before the production of hyphae; mutants form a thin 10-um layer of cells, primarily yeast cells, though a few elongated cells representing pseudohyphae are occasionally seen C. albicans orf19.4519 ORF SUV3 CAL0002663 PMID: 16087754|CGD_REF: CAL0114512 homozygous diploid, classical genetics null suv3::Tn7-UAU1/suv3::Tn7-URA3 BWP17 hyphal growth: absent M199 medium, pH 8, at 37 deg C for 12 h -alkaline medium completely defective in alkaline-induced hyphal morphogenesis C. albicans orf19.4519 ORF SUV3 CAL0002663 PMID: 20223293|CGD_REF: CAL0125139 homozygous diploid, classical genetics null BWP17 filamentous growth: absent in 10% hemolymph and in the presence of G. mellonella hemocytes C. albicans orf19.4520 ORF CAL0002682 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.4524 ORF ZCF24 CAL0002690 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.4524 ORF ZCF24 CAL0002690 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.4524 ORF ZCF24 CAL0002690 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.4524 ORF ZCF24 CAL0002690 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.4524 ORF ZCF24 CAL0002690 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.4526 ORF HSP30 CAL0002694 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.4527 ORF HGT1 CAL0002696 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.4527 ORF HGT1 CAL0002696 PMID: 12524333|CGD_REF: CAL0080691 homozygous diploid, systematic mutation set (homozygous insertion mutants generated with URA3-ARG4-URA3 (UAU1) cassette) null BWP17 inviable homozygous null mutant strain could not be recovered, suggesting that the gene is essential under the selection conditions C. albicans orf19.4527 ORF HGT1 CAL0002696 PMID: 21844307|CGD_REF: CAL0000142816 homozygous diploid, classical genetics null hgt1::LEU2/hgt1::HIS1 SN152 hyphal growth: decreased RPMI medium, 30 or 37 deg C C. albicans orf19.4527 ORF HGT1 CAL0002696 PMID: 21844307|CGD_REF: CAL0000142816 homozygous diploid, classical genetics null hgt1::LEU2/hgt1::HIS1 SN152 viable C. albicans orf19.4529 ORF CAL0002700 PMID: 14663094|CGD_REF: CAL0080633 homozygous diploid, systematic mutation set (homozygous insertion mutants generated with URA3-ARG4-URA3 (UAU1) cassette) null BWP17 viable C. albicans orf19.4530.1 ORF CAF0007014 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 invasive growth: decreased solid SLAD media C. albicans orf19.4531 ORF CAL0002718 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.4532 ORF CAL0002719 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.4533 ORF CAL0002721 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.4534 ORF CAL0002723 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.4535 ORF PTR3 CAL0002725 PMID: 14663094|CGD_REF: CAL0080633 homozygous diploid, systematic mutation set (homozygous insertion mutants generated with URA3-ARG4-URA3 (UAU1) cassette) null BWP17 viable C. albicans orf19.4536 ORF CYS4 CAL0002727 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.4537 ORF CAL0002729 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.4538 ORF CAL0002731 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.454 ORF SFL1 CAL0005730 PMID: 17766464|CGD_REF: CAL0118561 homozygous diploid, classical genetics null Not recorded flocculation: increased C. albicans orf19.454 ORF SFL1 CAL0005730 PMID: 20041210|CGD_REF: CAL0124764 homozygous diploid, systematic mutation set null SN152 resistance to chemicals: decreased flucytosine strongly sensitive C. albicans orf19.454 ORF SFL1 CAL0005730 PMID: 17715361|CGD_REF: CAL0118684 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.454 ORF SFL1 CAL0005730 PMID: 17766464|CGD_REF: CAL0118561 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.454 ORF SFL1 CAL0005730 PMID: 17715361|CGD_REF: CAL0118684 homozygous diploid, classical genetics null BWP17 hyphal growth: increased increased hyphal growth under non-hypha-inducing conditions C. albicans orf19.454 ORF SFL1 CAL0005730 PMID: 20041210|CGD_REF: CAL0124764 homozygous diploid, systematic mutation set null SN152 invasive growth: increased SD medium at 30 deg C; SD or YEPD media at 37 deg C strongly increased C. albicans orf19.454 ORF SFL1 CAL0005730 PMID: 20041210|CGD_REF: CAL0124764 homozygous diploid, systematic mutation set null SN152 colony appearance: abnormal Spider medium at 30 deg C increased colony wrinkling and reduced peripheral filamentation C. albicans orf19.454 ORF SFL1 CAL0005730 PMID: 17715361|CGD_REF: CAL0118684 homozygous diploid, classical genetics null Not recorded virulence: decreased mouse intravenous infection C. albicans orf19.454 ORF SFL1 CAL0005730 PMID: 17715361|CGD_REF: CAL0118684 heterozygous diploid, classical genetics overexpression Not recorded virulence: decreased mouse intravenous infection C. albicans orf19.4540 ORF UBC8 CAL0002753 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 invasive growth: decreased solid SLAD media C. albicans orf19.4542 ORF CAL0002756 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.4542 ORF CAL0002756 PMID: 21135205|CGD_REF: CAL0139967 heterozygous diploid, competitive growth (large-scale identification of genes essential for virulence in mouse) repressible CAI-4 virulence: decreased mouse intravenous infection C. albicans orf19.4543 ORF UGA2 CAL0002758 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.4543 ORF UGA2 CAL0002758 PMID: 14663094|CGD_REF: CAL0080633 homozygous diploid, systematic mutation set (homozygous insertion mutants generated with URA3-ARG4-URA3 (UAU1) cassette) null BWP17 viable C. albicans orf19.4543 ORF UGA2 CAL0002758 PMID: 23856128|CGD_REF: CAL0000172540 homozygous diploid, classical genetics null BWP17 resistance to chemicals: decreased propolis C. albicans orf19.4545 ORF SWI4 CAL0002762 PMID: 20041210|CGD_REF: CAL0124764 homozygous diploid, systematic mutation set null SN152 resistance to chemicals: decreased fenpropimorph strongly sensitive C. albicans orf19.4545 ORF SWI4 CAL0002762 PMID: 20041210|CGD_REF: CAL0124764 homozygous diploid, systematic mutation set null SN152 heat sensitivity: increased elevated temperature (42 deg C, SD medium) strongly sensitive C. albicans orf19.4545 ORF SWI4 CAL0002762 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.4545 ORF SWI4 CAL0002762 PMID: 20041210|CGD_REF: CAL0124764 homozygous diploid, systematic mutation set null SN152 colony appearance: abnormal YEPD plus serum medium at 37 deg C or Lee's medium pH 6.8 at 37 deg C strongly decreased colony fuzziness and/or peripheral filamentation C. albicans orf19.4545 ORF SWI4 CAL0002762 PMID: 20041210|CGD_REF: CAL0124764 homozygous diploid, systematic mutation set null SN152 colony color: abnormal CHROMagar medium at 30 and 37 deg C darker than normal C. albicans orf19.4545 ORF SWI4 CAL0002762 PMID: 20041210|CGD_REF: CAL0124764 homozygous diploid, systematic mutation set null SN152 resistance to chemicals: decreased caffeine severely sensitive C. albicans orf19.4545 ORF SWI4 CAL0002762 PMID: 21257795|CGD_REF: CAL0141410 homozygous diploid, classical genetics null BWP17 viable C. albicans orf19.4545 ORF SWI4 CAL0002762 PMID: 21257795|CGD_REF: CAL0141410 homozygous diploid, classical genetics null BWP17 cell size: increased C. albicans orf19.4545 ORF SWI4 CAL0002762 PMID: 21257795|CGD_REF: CAL0141410 homozygous diploid, classical genetics null BWP17 cell shape: abnormal elongated cells C. albicans orf19.4545 ORF SWI4 CAL0002762 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.4545 ORF SWI4 CAL0002762 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.4545 ORF SWI4 CAL0002762 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: decreased rate liquid synthetic complete medium C. albicans orf19.4545 ORF SWI4 CAL0002762 PMID: 20865172|CGD_REF: CAL0126252 homozygous diploid, classical genetics null SN95 resistance to chemicals: decreased fluconazole C. albicans orf19.4545 ORF SWI4 CAL0002762 PMID: 20865172|CGD_REF: CAL0126252 homozygous diploid, classical genetics null SN95 resistance to chemicals: decreased fenpropimorph C. albicans orf19.4545 ORF SWI4 CAL0002762 PMID: 20865172|CGD_REF: CAL0126252 homozygous diploid, classical genetics null SN95 resistance to chemicals: decreased terbinafine C. albicans orf19.4545 ORF SWI4 CAL0002762 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.4546 ORF HOL4 CAL0002764 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.4548 ORF MAK32 CAL0002767 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.4549 ORF FGR38 CAL0002769 PMID: 12773383|CGD_REF: CAL0087974 heterozygous diploid, classical genetics (haploinsufficient phenotype assay) null CAI-4 viable heterozygous transposon insertion C. albicans orf19.4549 ORF FGR38 CAL0002769 PMID: 12773383|CGD_REF: CAL0087974 heterozygous diploid, classical genetics (haploinsufficient phenotype assay) null CAI-4 filamentous growth: increased solid Spider medium heterozygous transposon insertion C. albicans orf19.4550 ORF CAL0002781 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.4551 ORF CTN1 CAL0002783 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.4551 ORF CTN1 CAL0002783 PMID: 18227254|CGD_REF: CAL0118865 homozygous diploid, classical genetics null SC5314 viable strain is Ura+ C. albicans orf19.4551 ORF CTN1 CAL0002783 PMID: 18227254|CGD_REF: CAL0118865 homozygous diploid, classical genetics null SC5314 hyphal growth: normal solid YP-glycerol, YP-serum, or M199, 37 deg C; strain is Ura+ C. albicans orf19.4551 ORF CTN1 CAL0002783 PMID: 18227254|CGD_REF: CAL0118865 homozygous diploid, classical genetics null SC5314 utilization of carbon source: decreased acetic acid strain is Ura+ C. albicans orf19.4551 ORF CTN1 CAL0002783 PMID: 18227254|CGD_REF: CAL0118865 homozygous diploid, classical genetics null SC5314 utilization of carbon source: decreased ethanol strain is Ura+ C. albicans orf19.4551 ORF CTN1 CAL0002783 PMID: 18227254|CGD_REF: CAL0118865 homozygous diploid, classical genetics null SC5314 utilization of carbon source: decreased citric acid strain is Ura+ C. albicans orf19.4551 ORF CTN1 CAL0002783 PMID: 18227254|CGD_REF: CAL0118865 homozygous diploid, classical genetics null SC5314 virulence: normal strain is Ura+ mouse intravenous infection C. albicans orf19.4555 ORF ALS4 CAL0002789 PMID: 15870470|CGD_REF: CAL0082507 homozygous diploid, classical genetics null CAI-4 germ tube formation: decreased liquid RPMI medium decrease is not observed in Lee's medium C. albicans orf19.4555 ORF ALS4 CAL0002789 PMID: 15870470|CGD_REF: CAL0082507 heterozygous diploid, classical genetics null Not recorded viable C. albicans orf19.4555 ORF ALS4 CAL0002789 PMID: 15870470|CGD_REF: CAL0082507 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.4555 ORF ALS4 CAL0002789 PMID: 15870470|CGD_REF: CAL0082507 homozygous diploid, classical genetics null Not recorded adhesion: decreased adhesion to vascular endothelial cells slight decrease C. albicans orf19.4555 ORF ALS4 CAL0002789 PMID: 15870470|CGD_REF: CAL0082507 homozygous diploid, classical genetics null Not recorded virulence: normal reconstituted human epithelium ex vivo model of infection C. albicans orf19.4563 ORF CAL0002825 PMID: 23572557|CGD_REF: CAL0000158900 homozygous diploid, classical genetics null BWP17 adhesion: decreased Fluxion Bioflux 200, equipped with a microscope, was used for adherence analysis allowing a constant flow of cells through microfluidic channels C. albicans orf19.4563 ORF CAL0002825 PMID: 23572557|CGD_REF: CAL0000158900 homozygous diploid, classical genetics null BWP17 resistance to chemicals: increased fluconazole RPMI+MOPS+Histidine medium , 6 hours without shaking at 37 degrees C 24 hr fluconazole treatment in 96 well plates C. albicans orf19.4565 ORF BGL2 CAL0002830 PMID: 9043114|CGD_REF: CAL0080795 homozygous diploid, classical genetics null Not recorded flocculation: increased especially during stationary phase C. albicans orf19.4565 ORF BGL2 CAL0002830 PMID: 9043114|CGD_REF: CAL0080795 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased Calcofluor White effect is slight C. albicans orf19.4565 ORF BGL2 CAL0002830 PMID: 9043114|CGD_REF: CAL0080795 homozygous diploid, classical genetics null Not recorded vegetative growth: decreased rate effect is slight C. albicans orf19.4565 ORF BGL2 CAL0002830 PMID: 9043114|CGD_REF: CAL0080795 homozygous diploid, classical genetics null Not recorded chemical compound accumulation: normal (1->6)-beta-D-glucan normal cell wall beta-1,6-glucan C. albicans orf19.4565 ORF BGL2 CAL0002830 PMID: 9043114|CGD_REF: CAL0080795 homozygous diploid, classical genetics null Not recorded chemical compound accumulation: normal mannan normal cell wall mannan content C. albicans orf19.4565 ORF BGL2 CAL0002830 PMID: 9043114|CGD_REF: CAL0080795 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased nikkomycin Z C. albicans orf19.4565 ORF BGL2 CAL0002830 PMID: 9043114|CGD_REF: CAL0080795 homozygous diploid, classical genetics null Not recorded chemical compound accumulation: normal (1->3)-beta-D-glucan normal cell wall beta-1,3-glucan C. albicans orf19.4565 ORF BGL2 CAL0002830 PMID: 22876186|CGD_REF: CAL0000157675 homozygous diploid, classical genetics null BWP17 biofilm formation: decreased C. albicans orf19.4565 ORF BGL2 CAL0002830 PMID: 22876186|CGD_REF: CAL0000157675 homozygous diploid, classical genetics null BWP17 resistance to chemicals: decreased fluconazole C. albicans orf19.4565 ORF BGL2 CAL0002830 PMID: 9043114|CGD_REF: CAL0080795 homozygous diploid, classical genetics null Not recorded virulence: decreased exhibits decreased kidney colonization mouse intravenous infection C. albicans orf19.4566 ORF CAL0002832 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.4566 ORF CAL0002832 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.4566 ORF CAL0002832 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.4566 ORF CAL0002832 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.4566 ORF CAL0002832 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.4566 ORF CAL0002832 PMID: 21135205|CGD_REF: CAL0139967 heterozygous diploid, competitive growth (large-scale identification of genes essential for virulence in mouse) repressible CAI-4 virulence: normal mouse intravenous infection C. albicans orf19.4567 ORF CAL0002834 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.4567 ORF CAL0002834 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.4567 ORF CAL0002834 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.4567 ORF CAL0002834 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.4567 ORF CAL0002834 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.4568 ORF ZCF25 CAL0002836 PMID: 15964282|CGD_REF: CAL0114274 homozygous diploid, systematic mutation set (split-marker transposon insertion strategy to disrupt both alleles) null BWP17 viable C. albicans orf19.4568 ORF ZCF25 CAL0002836 PMID: 19463063|CGD_REF: CAL0123630 homozygous diploid, systematic mutation set (split-marker transposon insertion strategy to disrupt both alleles) null BWP17 viable C. albicans orf19.4568 ORF ZCF25 CAL0002836 PMID: 15964282|CGD_REF: CAL0114274 homozygous diploid, systematic mutation set (split-marker transposon insertion strategy to disrupt both alleles) null BWP17 biofilm formation: normal C. albicans orf19.4568 ORF ZCF25 CAL0002836 PMID: 19463063|CGD_REF: CAL0123630 homozygous diploid, systematic mutation set (split-marker transposon insertion strategy to disrupt both alleles) null BWP17 virulence: normal Toll mutant D. melanogaster invasive infection insect infection C. albicans orf19.4569 ORF CAL0002838 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.4569 ORF CAL0002838 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.4569 ORF CAL0002838 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.4569 ORF CAL0002838 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.4569 ORF CAL0002838 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.457 ORF CAL0005737 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.4571 ORF CAL0002863 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.4573 ORF ZCF26 CAL0002868 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.4573 ORF ZCF26 CAL0002868 PMID: 15964282|CGD_REF: CAL0114274 homozygous diploid, systematic mutation set (split-marker transposon insertion strategy to disrupt both alleles) null BWP17 viable C. albicans orf19.4573 ORF ZCF26 CAL0002868 PMID: 15964282|CGD_REF: CAL0114274 homozygous diploid, systematic mutation set (split-marker transposon insertion strategy to disrupt both alleles) null BWP17 biofilm formation: normal C. albicans orf19.4573 ORF ZCF26 CAL0002868 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.4573 ORF ZCF26 CAL0002868 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.4573 ORF ZCF26 CAL0002868 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.4573 ORF ZCF26 CAL0002868 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.4574 ORF CAL0002871 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.4575 ORF CAL0002873 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.4575 ORF CAL0002873 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 invasive growth: decreased solid SLAD media C. albicans orf19.4577.3 ORF TIM10 CAF0007015 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.4578 ORF CYT2 CAL0002879 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.4579 ORF ERV29 CAL0002881 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.4581 ORF CAL0002903 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.4582 ORF CAL0002905 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.4583 ORF CAL0002908 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.4584 ORF PHO114 CAL0002910 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.4585 ORF TFG1 CAL0002912 PMID: 12773383|CGD_REF: CAL0087974 heterozygous diploid, classical genetics (haploinsufficient phenotype assay) unspecified CAI-4 filamentous growth: increased solid YEPD plus serum transposon insertion proximal to, but not within, the ORF C. albicans orf19.4585 ORF TFG1 CAL0002912 PMID: 21135205|CGD_REF: CAL0139967 heterozygous diploid, large-scale survey (large-scale identification of genes essential for virulence in mouse) repressible CAI-4 virulence: absent mouse intravenous infection C. albicans orf19.4587 ORF HGH1 CAL0002914 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.459 ORF ADP1 CAL0005745 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.459 ORF ADP1 CAL0005745 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.459 ORF ADP1 CAL0005745 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.459 ORF ADP1 CAL0005745 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.459 ORF ADP1 CAL0005745 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.4590 ORF RFX2 CAL0002933 PMID: 19252121|CGD_REF: CAL0122455 heterozygous diploid, classical genetics null Not recorded heat sensitivity: decreased heterozygous null mutant and reintegrant strains; heat resistance is intermediate between that of wild type and the homozygous null mutant C. albicans orf19.4590 ORF RFX2 CAL0002933 PMID: 19252121|CGD_REF: CAL0122455 homozygous diploid, classical genetics null Not recorded heat sensitivity: decreased C. albicans orf19.4590 ORF RFX2 CAL0002933 PMID: 19252121|CGD_REF: CAL0122455 heterozygous diploid, classical genetics null Not recorded UV resistance: normal heterozygous null mutant and reintegrant strains C. albicans orf19.4590 ORF RFX2 CAL0002933 PMID: 19252121|CGD_REF: CAL0122455 homozygous diploid, classical genetics null Not recorded UV resistance: decreased C. albicans orf19.4590 ORF RFX2 CAL0002933 PMID: 19252121|CGD_REF: CAL0122455 heterozygous diploid, classical genetics null Not recorded viable C. albicans orf19.4590 ORF RFX2 CAL0002933 PMID: 19252121|CGD_REF: CAL0122455 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.4590 ORF RFX2 CAL0002933 PMID: 19252121|CGD_REF: CAL0122455 homozygous diploid, classical genetics null Not recorded adhesion: increased adhesion to human buccal epithelial cells C. albicans orf19.4590 ORF RFX2 CAL0002933 PMID: 19252121|CGD_REF: CAL0122455 heterozygous diploid, classical genetics null Not recorded adhesion: normal C. albicans orf19.4590 ORF RFX2 CAL0002933 PMID: 19252121|CGD_REF: CAL0122455 heterozygous diploid, classical genetics null Not recorded invasive growth: normal solid YPD C. albicans orf19.4590 ORF RFX2 CAL0002933 PMID: 19252121|CGD_REF: CAL0122455 homozygous diploid, classical genetics null SC5314 invasive growth: increased C. albicans orf19.4590 ORF RFX2 CAL0002933 PMID: 19252121|CGD_REF: CAL0122455 heterozygous diploid, classical genetics null Not recorded resistance to chemicals: increased ethanol heterozygous null mutant and reintegrant strains; resistance is intermediate between that of wild type and the homozygous null mutant C. albicans orf19.4590 ORF RFX2 CAL0002933 PMID: 19252121|CGD_REF: CAL0122455 homozygous diploid, classical genetics null Not recorded resistance to chemicals: increased ethanol C. albicans orf19.4590 ORF RFX2 CAL0002933 PMID: 19252121|CGD_REF: CAL0122455 homozygous diploid, classical genetics null Not recorded oxidative stress resistance: normal hydrogen peroxide C. albicans orf19.4590 ORF RFX2 CAL0002933 PMID: 19252121|CGD_REF: CAL0122455 homozygous diploid, classical genetics null Not recorded resistance to chemicals: normal ethyl methanesulfonate C. albicans orf19.4590 ORF RFX2 CAL0002933 PMID: 19252121|CGD_REF: CAL0122455 homozygous diploid, classical genetics null Not recorded resistance to chemicals: normal methyl methanesulfonate C. albicans orf19.4590 ORF RFX2 CAL0002933 PMID: 19252121|CGD_REF: CAL0122455 homozygous diploid, classical genetics null Not recorded ionic stress resistance: normal sodium chloride C. albicans orf19.4590 ORF RFX2 CAL0002933 PMID: 19252121|CGD_REF: CAL0122455 homozygous diploid, classical genetics null SC5314 filamentous growth: increased solid YPD or Sabouraud dextrose media, or liquid YPD plus serum extra-long hyphae and persistent filamentation C. albicans orf19.4590 ORF RFX2 CAL0002933 PMID: 19252121|CGD_REF: CAL0122455 homozygous diploid, classical genetics null Not recorded resistance to chemicals: normal streptonigrin C. albicans orf19.4590 ORF RFX2 CAL0002933 PMID: 19252121|CGD_REF: CAL0122455 homozygous diploid, classical genetics null Not recorded resistance to chemicals: normal bleomycin C. albicans orf19.4590 ORF RFX2 CAL0002933 PMID: 19252121|CGD_REF: CAL0122455 homozygous diploid, classical genetics null Not recorded resistance to chemicals: normal hydroxyurea C. albicans orf19.4590 ORF RFX2 CAL0002933 PMID: 19252121|CGD_REF: CAL0122455 homozygous diploid, classical genetics null Not recorded virulence: decreased mouse intravenous infection C. albicans orf19.4590 ORF RFX2 CAL0002933 PMID: 19252121|CGD_REF: CAL0122455 homozygous diploid, classical genetics null Not recorded virulence: decreased mouse oropharyngeal infection C. albicans orf19.4591 ORF CAT2 CAL0002936 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.4591 ORF CAT2 CAL0002936 PMID: 18227254|CGD_REF: CAL0118865 homozygous diploid, classical genetics null SC5314 viable strain is Ura+ C. albicans orf19.4591 ORF CAT2 CAL0002936 PMID: 18281597|CGD_REF: CAL0118818 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.4591 ORF CAT2 CAL0002936 PMID: 18227254|CGD_REF: CAL0118865 homozygous diploid, classical genetics null SC5314 hyphal growth: normal solid YP-glycerol, YP-serum, or M199, 37 deg C; strain is Ura+ C. albicans orf19.4591 ORF CAT2 CAL0002936 PMID: 18227254|CGD_REF: CAL0118865 homozygous diploid, classical genetics null SC5314 utilization of carbon source: decreased acetic acid strain is Ura+ C. albicans orf19.4591 ORF CAT2 CAL0002936 PMID: 18281597|CGD_REF: CAL0118818 homozygous diploid, classical genetics null Not recorded utilization of carbon source: absent acetic acid C. albicans orf19.4591 ORF CAT2 CAL0002936 PMID: 18227254|CGD_REF: CAL0118865 homozygous diploid, classical genetics null SC5314 utilization of carbon source: decreased oleic acid strain is Ura+ C. albicans orf19.4591 ORF CAT2 CAL0002936 PMID: 18227254|CGD_REF: CAL0118865 homozygous diploid, classical genetics null SC5314 utilization of carbon source: decreased ethanol strain is Ura+ C. albicans orf19.4591 ORF CAT2 CAL0002936 PMID: 18281597|CGD_REF: CAL0118818 homozygous diploid, classical genetics null Not recorded utilization of carbon source: absent ethanol C. albicans orf19.4591 ORF CAT2 CAL0002936 PMID: 18281597|CGD_REF: CAL0118818 homozygous diploid, classical genetics null Not recorded utilization of carbon source: absent fatty acid C. albicans orf19.4591 ORF CAT2 CAL0002936 PMID: 18281597|CGD_REF: CAL0118818 homozygous diploid, classical genetics null Other C. albicans biofilm formation: decreased C. albicans orf19.4591 ORF CAT2 CAL0002936 PMID: 18227254|CGD_REF: CAL0118865 homozygous diploid, classical genetics null SC5314 virulence: normal strain is Ura+ mouse intravenous infection C. albicans orf19.4591 ORF CAT2 CAL0002936 PMID: 18281597|CGD_REF: CAL0118818 homozygous diploid, classical genetics null Not recorded virulence: normal mouse intravenous infection C. albicans orf19.4592 ORF HSX11 CAL0002939 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.4592 ORF HSX11 CAL0002939 PMID: 11443131|CGD_REF: CAL0085475 homozygous diploid, classical genetics null Not recorded viable no obvious growth or filamentation defects C. albicans orf19.4592 ORF HSX11 CAL0002939 PMID: 11443131|CGD_REF: CAL0085475 heterozygous diploid, classical genetics null Not recorded viable C. albicans orf19.4592 ORF HSX11 CAL0002939 PMID: 20019081|CGD_REF: CAL0124887 homozygous diploid, classical genetics null Other C. albicans hyphal growth: decreased rate C. albicans orf19.4592 ORF HSX11 CAL0002939 PMID: 20019081|CGD_REF: CAL0124887 homozygous diploid, classical genetics null Other C. albicans resistance to chemicals: decreased sodium dodecyl sulfate C. albicans orf19.4592 ORF HSX11 CAL0002939 PMID: 20019081|CGD_REF: CAL0124887 homozygous diploid, classical genetics null Other C. albicans resistance to chemicals: decreased fluconazole C. albicans orf19.4592 ORF HSX11 CAL0002939 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.4592 ORF HSX11 CAL0002939 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.4592 ORF HSX11 CAL0002939 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, classical genetics null SN152 virulence: decreased BALB/c mice mouse intravenous infection C. albicans orf19.4592 ORF HSX11 CAL0002939 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, classical genetics null SN152 chemical compound accumulation: absent glucosylceramide mature glucosylceramide is absent from cellular membranes C. albicans orf19.4592 ORF HSX11 CAL0002939 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.4592 ORF HSX11 CAL0002939 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.4593 ORF RGA2 CAL0002942 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.4593 ORF RGA2 CAL0002942 PMID: 17093060|CGD_REF: CAL0117112 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.4593 ORF RGA2 CAL0002942 PMID: 17673907|CGD_REF: CAL0118285 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.4593 ORF RGA2 CAL0002942 PMID: 17093060|CGD_REF: CAL0117112 heterozygous diploid, classical genetics reduction of function rga2-K1061A/rga2 null BWP17 cellular morphology: abnormal polarized growth is enhanced C. albicans orf19.4593 ORF RGA2 CAL0002942 PMID: 17093060|CGD_REF: CAL0117112 heterozygous diploid, classical genetics reduction of function rga2-R1015L/rga2 null BWP17 cellular morphology: abnormal polarized growth is enhanced C. albicans orf19.4593 ORF RGA2 CAL0002942 PMID: 17093060|CGD_REF: CAL0117112 homozygous diploid, classical genetics null Not recorded cell shape: abnormal cells are elongated C. albicans orf19.4593 ORF RGA2 CAL0002942 PMID: 17673907|CGD_REF: CAL0118285 homozygous diploid, classical genetics null Not recorded cell shape: abnormal cells are elongated with abnormally wide bud necks C. albicans orf19.4593 ORF RGA2 CAL0002942 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: decreased growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.4593 ORF RGA2 CAL0002942 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.4593 ORF RGA2 CAL0002942 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.4593 ORF RGA2 CAL0002942 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.4594 ORF CLC1 CAL0002945 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.4599 ORF PHO89 CAL0002956 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.460 ORF CEK2 CAL0005756 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.460 ORF CEK2 CAL0005756 PMID: 12453219|CGD_REF: CAL0080981 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.460 ORF CEK2 CAL0005756 PMID: 12549007|CGD_REF: CAL0080982 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.460 ORF CEK2 CAL0005756 PMID: 12453219|CGD_REF: CAL0080981 homozygous diploid, classical genetics null Not recorded mating efficiency: decreased C. albicans orf19.460 ORF CEK2 CAL0005756 PMID: 18162580|CGD_REF: CAL0118948 homozygous diploid, classical genetics null Not recorded mating response: abnormal reduced and delayed shmoo formation in opaque cells in response to alpha pheromone C. albicans orf19.460 ORF CEK2 CAL0005756 PMID: 18162580|CGD_REF: CAL0118948 homozygous diploid, classical genetics null Not recorded phenotypic switching: normal C. albicans orf19.460 ORF CEK2 CAL0005756 PMID: 18162580|CGD_REF: CAL0118948 homozygous diploid, classical genetics null Not recorded pheromone sensitivity: decreased alpha factor reduced aggregation of white-phase cells C. albicans orf19.460 ORF CEK2 CAL0005756 PMID: 12773383|CGD_REF: CAL0087974 heterozygous diploid, classical genetics (haploinsufficient phenotype assay) unspecified CAI-4 filamentous growth: increased solid Spider medium transposon insertion proximal to, but not within, the ORF C. albicans orf19.460 ORF CEK2 CAL0005756 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.460 ORF CEK2 CAL0005756 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.460 ORF CEK2 CAL0005756 PMID: 18162580|CGD_REF: CAL0118948 homozygous diploid, classical genetics null P37005 biofilm formation: decreased white cells form a biofilm of reduced thickness in the presence of opaque cells of the opposite mating type C. albicans orf19.460 ORF CEK2 CAL0005756 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.460 ORF CEK2 CAL0005756 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.4601 ORF CAL0003581 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.4602 ORF MDH1-1 CAL0003583 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.4603 ORF ARL1 CAL0003584 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, competitive growth (haploinsufficient phenotype assay, barcode deletion set) null SC5314 resistance to chemicals: decreased brefeldin A C. albicans orf19.4603 ORF ARL1 CAL0003584 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.4603 ORF ARL1 CAL0003584 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: decreased growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.4603 ORF ARL1 CAL0003584 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: abnormal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.4603 ORF ARL1 CAL0003584 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.4603 ORF ARL1 CAL0003584 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.4606 ORF ERG8 CAL0003589 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.4606 ORF ERG8 CAL0003589 PMID: 21135205|CGD_REF: CAL0139967 heterozygous diploid, large-scale survey (large-scale identification of genes essential for virulence in mouse) repressible CAI-4 virulence: absent mouse intravenous infection C. albicans orf19.4612 ORF CAL0003611 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.4612 ORF CAL0003611 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 invasive growth: decreased solid SLAD media C. albicans orf19.4614 ORF CAL0003613 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.4615 ORF CAL0003615 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 invasive growth: decreased solid SLAD media C. albicans orf19.4616 ORF POL30 CAL0003616 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.4617 ORF CAL0003617 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.4618 ORF FBA1 CAL0003619 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.4618 ORF FBA1 CAL0003619 PMID: 16896220|CGD_REF: CAL0116432 heterozygous diploid, classical genetics repressible Not recorded inviable growth arrest when depleted below 5% C. albicans orf19.4618 ORF FBA1 CAL0003619 PMID: 16896220|CGD_REF: CAL0116432 homozygous diploid, classical genetics null Not recorded inviable homozygous null mutant strain could not be recovered, suggesting that the gene is essential under the selection conditions C. albicans orf19.4618 ORF FBA1 CAL0003619 PMID: 16896220|CGD_REF: CAL0116432 heterozygous diploid, classical genetics repressible Not recorded virulence: decreased mouse intravenous infection C. albicans orf19.4618 ORF FBA1 CAL0003619 PMID: 21135205|CGD_REF: CAL0139967 heterozygous diploid, large-scale survey (large-scale identification of genes essential for virulence in mouse) repressible CAI-4 virulence: absent mouse intravenous infection C. albicans orf19.4620 ORF TIM12 CAL0003633 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.4621 ORF CAL0003635 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.4624 ORF HRT2 CAL0003640 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.4625 ORF TOA2 CAL0003642 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.4626 ORF CAL0003644 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.4628 ORF CAL0003648 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.4628 ORF CAL0003648 PMID: 19623926|CGD_REF: CAL0124054 heterozygous diploid, competitive growth (haploinsufficient phenotype assay, barcode deletion set) null SC5314 resistance to chemicals: decreased parnafungin C. albicans orf19.4628 ORF CAL0003648 PMID: 21135205|CGD_REF: CAL0139967 heterozygous diploid, competitive growth (large-scale identification of genes essential for virulence in mouse) repressible CAI-4 virulence: decreased mouse intravenous infection C. albicans orf19.4629 ORF CAL0003650 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 invasive growth: decreased solid SLAD media C. albicans orf19.4630 ORF CPA1 CAL0003663 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.4631 ORF ERG251 CAL0003665 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.4631 ORF ERG251 CAL0003665 PMID: 21135205|CGD_REF: CAL0139967 heterozygous diploid, competitive growth (large-scale identification of genes essential for virulence in mouse) repressible CAI-4 virulence: normal mouse intravenous infection C. albicans orf19.4632 ORF RPL20B CAL0003667 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.4633 ORF CAL0003668 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.4635 ORF NIP1 CAL0003672 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.4635 ORF NIP1 CAL0003672 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, competitive growth (haploinsufficient phenotype assay, barcode deletion set) null SC5314 resistance to chemicals: decreased verrucarin C. albicans orf19.4635 ORF NIP1 CAL0003672 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, competitive growth (haploinsufficient phenotype assay, barcode deletion set) null SC5314 resistance to chemicals: decreased roridin A C. albicans orf19.4639 ORF CAL0003680 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.4639 ORF CAL0003680 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.4639 ORF CAL0003680 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.4639 ORF CAL0003680 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.4640 ORF PWP1 CAL0003692 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.4640 ORF PWP1 CAL0003692 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: decreased growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.4640 ORF PWP1 CAL0003692 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, classical genetics null SN152 germ tube formation: decreased serum-containing medium C. albicans orf19.4640 ORF PWP1 CAL0003692 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: decreased rate liquid synthetic complete medium C. albicans orf19.4640 ORF PWP1 CAL0003692 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.4641 ORF NMT1 CAL0003694 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.4641 ORF NMT1 CAL0003694 PMID: 14507372|CGD_REF: CAL0088818 heterozygous diploid, large-scale survey (large-scale identification of essential genes by gene replacement and conditional expression (GRACE) method) repressible CAI-4 inviable one allele is deleted and the other is placed under repressible Tet promoter C. albicans orf19.4641 ORF NMT1 CAL0003694 PMID: 16607011|CGD_REF: CAL0115846 heterozygous diploid, classical genetics repressible SC5314 inviable C. albicans orf19.4641 ORF NMT1 CAL0003694 PMID: 7565086|CGD_REF: CAL0081587 heterozygous diploid, classical genetics conditional nmt1-G447D/nmt1 null CAI-4 heat sensitivity: increased 37 deg C in absence of myristate G447D mutation causes decrease in enzyme efficiency C. albicans orf19.4641 ORF NMT1 CAL0003694 PMID: 7565086|CGD_REF: CAL0081587 heterozygous diploid, classical genetics conditional nmt1-G447D/nmt1 null CAI-4 virulence: absent immunosuppressed mouse intravenous infection C. albicans orf19.4641 ORF NMT1 CAL0003694 PMID: 9043113|CGD_REF: CAL0080772 unknown ploidy, classical genetics reduction of function Other C. albicans auxotrophy mutant shows decreased affinity for substrate, and activity is required for growth C. albicans orf19.4641 ORF NMT1 CAL0003694 PMID: 9043113|CGD_REF: CAL0080772 unknown ploidy, classical genetics reduction of function Other C. albicans viable C. albicans orf19.4641 ORF NMT1 CAL0003694 PMID: 16607011|CGD_REF: CAL0115846 homozygous diploid, classical genetics null BWP17 inviable homozygous null mutant strain could not be recovered, suggesting that the gene is essential under the selection conditions C. albicans orf19.4641 ORF NMT1 CAL0003694 PMID: 16607011|CGD_REF: CAL0115846 heterozygous diploid, classical genetics null BWP17 viable C. albicans orf19.4641 ORF NMT1 CAL0003694 PMID: 7565086|CGD_REF: CAL0081587 homozygous diploid, classical genetics null CAI-4 inviable homozygous null mutant strain could not be recovered, suggesting that the gene is essential under the selection conditions C. albicans orf19.4641 ORF NMT1 CAL0003694 PMID: 7565086|CGD_REF: CAL0081587 heterozygous diploid, classical genetics null CAI-4 viable C. albicans orf19.4641 ORF NMT1 CAL0003694 PMID: 7565086|CGD_REF: CAL0081587 heterozygous diploid, classical genetics null CAI-4 virulence: normal immunosuppressed mouse intravenous infection C. albicans orf19.4641 ORF NMT1 CAL0003694 PMID: 9043113|CGD_REF: CAL0080772 heterozygous diploid, classical genetics null Other C. albicans viable C. albicans orf19.4642 ORF CAL0003696 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient YPD medium C. albicans orf19.4642 ORF CAL0003696 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 invasive growth: decreased solid SLAD media C. albicans orf19.4645 ORF BEM1 CAL0003701 PMID: 12582118|CGD_REF: CAL0080793 heterozygous diploid, classical genetics repressible BWP17 vegetative growth: decreased rate C. albicans orf19.4645 ORF BEM1 CAL0003701 PMID: 12582118|CGD_REF: CAL0080793 heterozygous diploid, classical genetics repressible BWP17 viable C. albicans orf19.4645 ORF BEM1 CAL0003701 PMID: 12366849|CGD_REF: CAL0080792 heterozygous diploid, classical genetics repressible CAI-4 hyphal growth: abnormal RPMI 1640 medium plus serum C. albicans orf19.4645 ORF BEM1 CAL0003701 PMID: 12582118|CGD_REF: CAL0080793 heterozygous diploid, classical genetics repressible BWP17 hyphal growth: normal solid YEPD plus serum C. albicans orf19.4645 ORF BEM1 CAL0003701 PMID: 12366849|CGD_REF: CAL0080792 homozygous diploid, classical genetics null Not recorded inviable cells show reduced budding, lack of daughter cell separation, abnormal morphology, and lysis after excision of BEM1 C. albicans orf19.4645 ORF BEM1 CAL0003701 PMID: 12582118|CGD_REF: CAL0080793 heterozygous diploid, classical genetics misexpression BWP17 virulence: decreased mouse intravenous infection C. albicans orf19.4646 ORF UEC1 CAL0003703 PMID: 19700637|CGD_REF: CAL0124157 homozygous diploid, classical genetics null Not recorded toxin resistance: decreased human neutrophil defensin-1, h-beta-D-2, RP-1, RP-11, and RP-13, but not histatin-5 C. albicans orf19.4646 ORF UEC1 CAL0003703 PMID: 19700637|CGD_REF: CAL0124157 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased sodium dodecyl sulfate C. albicans orf19.4646 ORF UEC1 CAL0003703 PMID: 19700637|CGD_REF: CAL0124157 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.4646 ORF UEC1 CAL0003703 PMID: 19700637|CGD_REF: CAL0124157 homozygous diploid, classical genetics null BWP17 hyphal growth: abnormal hyphae are thicker than wild-type C. albicans orf19.4646 ORF UEC1 CAL0003703 PMID: 19700637|CGD_REF: CAL0124157 homozygous diploid, classical genetics null Not recorded ionic stress resistance: decreased sodium chloride C. albicans orf19.4646 ORF UEC1 CAL0003703 PMID: 19700637|CGD_REF: CAL0124157 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased protamine C. albicans orf19.4646 ORF UEC1 CAL0003703 PMID: 19700637|CGD_REF: CAL0124157 homozygous diploid, classical genetics null Not recorded virulence: decreased oral epithelial cells decreased capacity to damage cells in vitro model of infection C. albicans orf19.4647 ORF HAP3 CAL0003705 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.4647 ORF HAP3 CAL0003705 PMID: 17880264|CGD_REF: CAL0118619 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.4647 ORF HAP3 CAL0003705 PMID: 17880264|CGD_REF: CAL0118619 homozygous diploid, classical genetics null Not recorded phenotypic switching: normal MTLa/MTLa background white-to-opaque switching C. albicans orf19.4647 ORF HAP3 CAL0003705 PMID: 21592964|CGD_REF: CAL0142015 homozygous diploid, classical genetics null SN152 resistance to chemicals: decreased BPS impaired for growth in iron chelating BPS medium C. albicans orf19.4649 ORF ZCF27 CAL0003708 PMID: 15964282|CGD_REF: CAL0114274 homozygous diploid, systematic mutation set (split-marker transposon insertion strategy to disrupt both alleles) null BWP17 inviable homozygous null mutant strain could not be recovered, suggesting that the gene is essential under the selection conditions C. albicans orf19.4649 ORF ZCF27 CAL0003708 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.4649 ORF ZCF27 CAL0003708 PMID: 22073120|CGD_REF: CAL0000143592 homozygous diploid, classical genetics null BWP17 viable C. albicans orf19.4649 ORF ZCF27 CAL0003708 PMID: 22073120|CGD_REF: CAL0000143592 homozygous diploid, classical genetics null BWP17 invasive growth: decreased decreased agar invasion C. albicans orf19.4649 ORF ZCF27 CAL0003708 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: abnormal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.4649 ORF ZCF27 CAL0003708 PMID: 22073120|CGD_REF: CAL0000143592 homozygous diploid, classical genetics null BWP17 viable C. albicans orf19.4649 ORF ZCF27 CAL0003708 PMID: 22073120|CGD_REF: CAL0000143592 homozygous diploid, classical genetics null BWP17 hyphal growth: increased C. albicans orf19.4649 ORF ZCF27 CAL0003708 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.4649 ORF ZCF27 CAL0003708 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.4650 ORF ILV6 CAL0003717 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.4653 ORF CAL0003721 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 invasive growth: decreased solid SLAD media C. albicans orf19.4655 ORF OPT6 CAL0003725 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.4655 ORF OPT6 CAL0003725 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, competitive growth (haploinsufficient phenotype assay, barcode deletion set) null SC5314 resistance to chemicals: decreased ergosterol analogs (ECC69 and/or ECC1384) C. albicans orf19.4655 ORF OPT6 CAL0003725 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.4655 ORF OPT6 CAL0003725 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.4655 ORF OPT6 CAL0003725 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.4655 ORF OPT6 CAL0003725 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.4657 ORF CAL0003729 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.4657 ORF CAL0003729 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient YPD medium C. albicans orf19.4657 ORF CAL0003729 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient YNB medium C. albicans orf19.4657 ORF CAL0003729 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient SLAD medium C. albicans orf19.4658 ORF CAL0003730 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.4658 ORF CAL0003730 PMID: 14663094|CGD_REF: CAL0080633 homozygous diploid, systematic mutation set (homozygous insertion mutants generated with URA3-ARG4-URA3 (UAU1) cassette) null BWP17 viable C. albicans orf19.4658 ORF CAL0003730 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.4658 ORF CAL0003730 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.4658 ORF CAL0003730 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.4658 ORF CAL0003730 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.4659 ORF CAL0003731 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.4662 ORF RLM1 CAL0003752 PMID: 20041210|CGD_REF: CAL0124764 homozygous diploid, systematic mutation set null SN152 resistance to chemicals: decreased Calcofluor White severely sensitive C. albicans orf19.4662 ORF RLM1 CAL0003752 PMID: 16552442|CGD_REF: CAL0115731 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.4662 ORF RLM1 CAL0003752 PMID: 16552442|CGD_REF: CAL0115731 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased Congo Red C. albicans orf19.4662 ORF RLM1 CAL0003752 PMID: 16552442|CGD_REF: CAL0115731 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased caspofungin C. albicans orf19.4662 ORF RLM1 CAL0003752 PMID: 21666076|CGD_REF: CAL0000142107 homozygous diploid, classical genetics null rlm1::Tn7-UAU1/rlm1::Tn7-URA3 BWP17 resistance to chemicals: decreased fluconazole increased susceptibility to fluconazole in a biofilm C. albicans orf19.4662 ORF RLM1 CAL0003752 PMID: 24466000|CGD_REF: CAL0000173764 homozygous diploid, classical genetics null SC5314 resistance to chemicals: decreased Congo Red C. albicans orf19.4662 ORF RLM1 CAL0003752 PMID: 24466000|CGD_REF: CAL0000173764 homozygous diploid, classical genetics null SC5314 resistance to chemicals: decreased Calcofluor White C. albicans orf19.4662 ORF RLM1 CAL0003752 PMID: 24466000|CGD_REF: CAL0000173764 homozygous diploid, classical genetics null SC5314 resistance to chemicals: decreased caspofungin C. albicans orf19.4664 ORF NAT4 CAL0003754 PMID: 19555456|CGD_REF: CAL0123821 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.4664 ORF NAT4 CAL0003754 PMID: 19555456|CGD_REF: CAL0123821 homozygous diploid, classical genetics null Not recorded phenotypic switching: increased MTLa/MTLa background opaque-to-white switching C. albicans orf19.4664 ORF NAT4 CAL0003754 PMID: 19555456|CGD_REF: CAL0123821 homozygous diploid, classical genetics null Not recorded phenotypic switching: decreased MTLa/MTLa background white-to-opaque switching C. albicans orf19.4664 ORF NAT4 CAL0003754 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient YPD medium C. albicans orf19.4668 ORF CAL0003760 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.4668 ORF CAL0003760 PMID: 14663094|CGD_REF: CAL0080633 homozygous diploid, systematic mutation set (homozygous insertion mutants generated with URA3-ARG4-URA3 (UAU1) cassette) null BWP17 viable C. albicans orf19.4669 ORF AAT22 CAL0003762 PMID: 14663094|CGD_REF: CAL0080633 homozygous diploid, systematic mutation set (homozygous insertion mutants generated with URA3-ARG4-URA3 (UAU1) cassette) null BWP17 viable C. albicans orf19.467 ORF WOR3 CAL0005769 PMID: 23610392|CGD_REF: CAL0000171937 homozygous diploid, classical genetics overexpression MET3(p)-Wor3 SC5314 phenotypic switching: increased WOR3 overexpression in white cells at 25 degrees C results in mass switching to the opaque cell type C. albicans orf19.467 ORF WOR3 CAL0005769 PMID: 23610392|CGD_REF: CAL0000171937 homozygous diploid, classical genetics null SC5314 viable C. albicans orf19.4670 ORF CAS5 CAL0003780 PMID: 20041210|CGD_REF: CAL0124764 homozygous diploid, systematic mutation set null SN152 resistance to chemicals: decreased fluconazole severely sensitive C. albicans orf19.4670 ORF CAS5 CAL0003780 PMID: 20041210|CGD_REF: CAL0124764 homozygous diploid, systematic mutation set null SN152 resistance to chemicals: decreased fluphenazine (1 mM) severely sensitive C. albicans orf19.4670 ORF CAS5 CAL0003780 PMID: 20041210|CGD_REF: CAL0124764 homozygous diploid, systematic mutation set null SN152 resistance to chemicals: decreased fenpropimorph severely sensitive C. albicans orf19.4670 ORF CAS5 CAL0003780 PMID: 15964282|CGD_REF: CAL0114274 homozygous diploid, systematic mutation set (split-marker transposon insertion strategy to disrupt both alleles) null BWP17 viable C. albicans orf19.4670 ORF CAS5 CAL0003780 PMID: 16552442|CGD_REF: CAL0115731 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.4670 ORF CAS5 CAL0003780 PMID: 19463063|CGD_REF: CAL0123630 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.4670 ORF CAS5 CAL0003780 PMID: 19666778|CGD_REF: CAL0123941 homozygous diploid, classical genetics null BWP17 hyphal growth: decreased in C. elegans C. elegans infection C. albicans orf19.4670 ORF CAS5 CAL0003780 PMID: 19666778|CGD_REF: CAL0123941 homozygous diploid, classical genetics null BWP17 hyphal growth: normal Spider medium at 37 deg C C. albicans orf19.4670 ORF CAS5 CAL0003780 PMID: 15964282|CGD_REF: CAL0114274 homozygous diploid, systematic mutation set (split-marker transposon insertion strategy to disrupt both alleles) null BWP17 biofilm formation: normal C. albicans orf19.4670 ORF CAS5 CAL0003780 PMID: 20041210|CGD_REF: CAL0124764 homozygous diploid, systematic mutation set null SN152 cold sensitivity: increased reduced temperature (16 deg C, SD medium) severely sensitive C. albicans orf19.4670 ORF CAS5 CAL0003780 PMID: 20041210|CGD_REF: CAL0124764 homozygous diploid, systematic mutation set null SN152 colony appearance: abnormal Spider medium at 30 deg C strongly increased colony wrinkling and reduced peripheral filamentation C. albicans orf19.4670 ORF CAS5 CAL0003780 PMID: 20041210|CGD_REF: CAL0124764 homozygous diploid, systematic mutation set null SN152 colony color: abnormal CHROMagar medium at 30 and 37 deg C darker than normal C. albicans orf19.4670 ORF CAS5 CAL0003780 PMID: 20041210|CGD_REF: CAL0124764 homozygous diploid, systematic mutation set null SN152 metal resistance: increased copper(2+) strongly resistant C. albicans orf19.4670 ORF CAS5 CAL0003780 PMID: 16552442|CGD_REF: CAL0115731 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased Congo Red C. albicans orf19.4670 ORF CAS5 CAL0003780 PMID: 19463063|CGD_REF: CAL0123630 homozygous diploid, classical genetics null BWP17 filamentous growth: normal C. albicans orf19.4670 ORF CAS5 CAL0003780 PMID: 16552442|CGD_REF: CAL0115731 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased caspofungin C. albicans orf19.4670 ORF CAS5 CAL0003780 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.4670 ORF CAS5 CAL0003780 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: abnormal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.4670 ORF CAS5 CAL0003780 PMID: 22359502|CGD_REF: CAL0000144048 homozygous diploid, classical genetics null BWP17 adhesion: decreased insertion mutant, independent SN152 deletion mutant strain also tested C. albicans orf19.4670 ORF CAS5 CAL0003780 PMID: 22359502|CGD_REF: CAL0000144048 homozygous diploid, classical genetics null BWP17 viable insertion mutant, independent SN152 deletion mutant strain also tested C. albicans orf19.4670 ORF CAS5 CAL0003780 PMID: 19463063|CGD_REF: CAL0123630 homozygous diploid, systematic mutation set (split-marker transposon insertion strategy to disrupt both alleles) null BWP17 virulence: decreased Toll mutant D. melanogaster invasive infection insect infection C. albicans orf19.4670 ORF CAS5 CAL0003780 PMID: 19666778|CGD_REF: CAL0123941 homozygous diploid, classical genetics null Not recorded virulence: decreased C. elegans infection C. albicans orf19.4670 ORF CAS5 CAL0003780 PMID: 19463063|CGD_REF: CAL0123630 homozygous diploid, classical genetics null BWP17 virulence: decreased Toll mutant D. melanogaster invasive infection insect infection C. albicans orf19.4670 ORF CAS5 CAL0003780 PMID: 19463063|CGD_REF: CAL0123630 heterozygous diploid, classical genetics null BWP17 virulence: normal Toll mutant D. melanogaster invasive infection insect infection C. albicans orf19.4670 ORF CAS5 CAL0003780 PMID: 19463063|CGD_REF: CAL0123630 homozygous diploid, classical genetics null BWP17 virulence: absent BALB/c mice mouse intravenous infection C. albicans orf19.4670 ORF CAS5 CAL0003780 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.4670 ORF CAS5 CAL0003780 PMID: 20140194|CGD_REF: CAL0124995 homozygous diploid, classical genetics null Other C. albicans resistance to chemicals: decreased caspofungin C. albicans orf19.4670 ORF CAS5 CAL0003780 PMID: 20140194|CGD_REF: CAL0124995 homozygous diploid, classical genetics null Other C. albicans viable C. albicans orf19.4670 ORF CAS5 CAL0003780 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.4673 ORF BMT9 CAL0003785 PMID: 18234669|CGD_REF: CAL0119018 homozygous diploid, classical genetics null Not recorded resistance to chemicals: normal Calcofluor White C. albicans orf19.4673 ORF BMT9 CAL0003785 PMID: 18234669|CGD_REF: CAL0119018 homozygous diploid, classical genetics null Not recorded resistance to chemicals: normal sodium dodecyl sulfate C. albicans orf19.4673 ORF BMT9 CAL0003785 PMID: 18234669|CGD_REF: CAL0119018 homozygous diploid, classical genetics null Not recorded viable rich medium wild-type growth rate C. albicans orf19.4673 ORF BMT9 CAL0003785 PMID: 18234669|CGD_REF: CAL0119018 homozygous diploid, classical genetics null BWP17 hyphal growth: normal serum-containing medium C. albicans orf19.4673 ORF BMT9 CAL0003785 PMID: 18234669|CGD_REF: CAL0119018 homozygous diploid, classical genetics null Not recorded chlamydospore formation: normal RAT medium C. albicans orf19.4673 ORF BMT9 CAL0003785 PMID: 18234669|CGD_REF: CAL0119018 homozygous diploid, classical genetics null Not recorded ionic stress resistance: normal sodium chloride C. albicans orf19.4673 ORF BMT9 CAL0003785 PMID: 18234669|CGD_REF: CAL0119018 homozygous diploid, classical genetics null Not recorded resistance to chemicals: normal calcium dichloride C. albicans orf19.4675 ORF ASK1 CAL0003789 PMID: 21571923|CGD_REF: CAL0142042 homozygous diploid, classical genetics repressible ask1::HIS1/MET3(p)-ASK1 Other C. albicans inviable repressing conditions C. albicans orf19.4675 ORF ASK1 CAL0003789 PMID: 21571923|CGD_REF: CAL0142042 homozygous diploid, classical genetics repressible ask1::HIS1/MET3(p)-ASK1 Other C. albicans cell cycle progression: arrested repressing conditions mutant accumulates large budded cells after 4h of growth under nonpermissive conditions, prolonged incubation leads to a transition to an elongated (pseudohyphal-like) bud C. albicans orf19.4675 ORF ASK1 CAL0003789 PMID: 21571923|CGD_REF: CAL0142042 homozygous diploid, classical genetics repressible ask1::HIS1/MET3(p)-ASK1 Other C. albicans chromosome segregation: abnormal repressing conditions C. albicans orf19.4678 ORF CAL0003795 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.4678 ORF CAL0003795 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.4678 ORF CAL0003795 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.4678 ORF CAL0003795 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.4678 ORF CAL0003795 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.4680 ORF CAL0003814 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.4680 ORF CAL0003814 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, competitive growth (haploinsufficient phenotype assay, barcode deletion set) null SC5314 resistance to chemicals: decreased ergosterol analogs (ECC69 and/or ECC1384) C. albicans orf19.4680 ORF CAL0003814 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.4680 ORF CAL0003814 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.4680 ORF CAL0003814 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.4680 ORF CAL0003814 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.4681 ORF RAT1 CAL0003816 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.4682 ORF HGT17 CAL0003818 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.4683 ORF MLP1 CAL0003820 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.4688 ORF DAG7 CAL0003828 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.4688 ORF DAG7 CAL0003828 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, competitive growth (haploinsufficient phenotype assay, barcode deletion set) null SC5314 resistance to chemicals: decreased ergosterol analogs (ECC69 and/or ECC1384) C. albicans orf19.4688 ORF DAG7 CAL0003828 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.4688 ORF DAG7 CAL0003828 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.4688 ORF DAG7 CAL0003828 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.4688 ORF DAG7 CAL0003828 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.4689 ORF PGA57 CAL0003830 PMID: 18765290|CGD_REF: CAL0119430 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.469 ORF HST7 CAL0005777 PMID: 8917572|CGD_REF: CAL0081090 homozygous diploid, classical genetics null CAI-4 germ tube formation: normal solid or liquid serum-containing medium, or liquid Lee's medium C. albicans orf19.469 ORF HST7 CAL0005777 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.469 ORF HST7 CAL0005777 PMID: 20100861|CGD_REF: CAL0124920 homozygous diploid, classical genetics null chemical compound accumulation: increased beta-D-glucan increased beta-glucan exposure on the cell wall surface C. albicans orf19.469 ORF HST7 CAL0005777 PMID: 9596738|CGD_REF: CAL0080971 homozygous diploid, classical genetics null CAI-4 hyphal growth: abnormal solid SLAD medium decreased and aberrant hyphal growth C. albicans orf19.469 ORF HST7 CAL0005777 PMID: 8917572|CGD_REF: CAL0081090 homozygous diploid, classical genetics null CAI-4 hyphal growth: decreased solid Spider, Lee's, or M199 pH 7 media fails to form peripheral hyphae on solid Spider medium C. albicans orf19.469 ORF HST7 CAL0005777 PMID: 8917572|CGD_REF: CAL0081090 heterozygous diploid, classical genetics null CAI-4 hyphal growth: decreased solid Spider medium heterozygous null and reintegrant show intermediate phenotype between homozygous null and wild-type C. albicans orf19.469 ORF HST7 CAL0005777 PMID: 8917572|CGD_REF: CAL0081090 homozygous diploid, classical genetics null CAI-4 hyphal growth: abnormal solid Spider medium peripheral hyphae are not formed C. albicans orf19.469 ORF HST7 CAL0005777 PMID: 8917571|CGD_REF: CAL0081089 homozygous diploid, classical genetics null CAI-4 hyphal growth: decreased solid Spider medium plus galactose, mannose, or raffinose severe decrease C. albicans orf19.469 ORF HST7 CAL0005777 PMID: 8917571|CGD_REF: CAL0081089 homozygous diploid, classical genetics null CAI-4 hyphal growth: normal liquid media C. albicans orf19.469 ORF HST7 CAL0005777 PMID: 8917571|CGD_REF: CAL0081089 homozygous diploid, classical genetics null CAI-4 hyphal growth: absent solid Spider medium plus mannitol or sorbitol C. albicans orf19.469 ORF HST7 CAL0005777 PMID: 8917571|CGD_REF: CAL0081089 homozygous diploid, classical genetics null CAI-4 hyphal growth: normal solid Spider plus glucose or GlcNAc; Lee's; serum-containing; or rice agar media C. albicans orf19.469 ORF HST7 CAL0005777 PMID: 8917572|CGD_REF: CAL0081090 homozygous diploid, classical genetics null CAI-4 hyphal growth: decreased solid Spider, Lee's, or M199 pH 7 media C. albicans orf19.469 ORF HST7 CAL0005777 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.469 ORF HST7 CAL0005777 PMID: 9596738|CGD_REF: CAL0080971 unknown ploidy, classical genetics overexpression CAI-4 viable C. albicans orf19.469 ORF HST7 CAL0005777 PMID: 8917571|CGD_REF: CAL0081089 homozygous diploid, classical genetics null CAI-4 viable C. albicans orf19.469 ORF HST7 CAL0005777 PMID: 8917572|CGD_REF: CAL0081090 homozygous diploid, classical genetics null CAI-4 viable C. albicans orf19.469 ORF HST7 CAL0005777 PMID: 9596738|CGD_REF: CAL0080971 homozygous diploid, classical genetics null CAI-4 viable C. albicans orf19.469 ORF HST7 CAL0005777 PMID: 8917571|CGD_REF: CAL0081089 heterozygous diploid, classical genetics null CAI-4 viable C. albicans orf19.469 ORF HST7 CAL0005777 PMID: 8917571|CGD_REF: CAL0081089 homozygous diploid, classical genetics null CAI-4 virulence: normal mouse intravenous infection C. albicans orf19.469 ORF HST7 CAL0005777 PMID: 8917572|CGD_REF: CAL0081090 heterozygous diploid, classical genetics null CAI-4 viable C. albicans orf19.469 ORF HST7 CAL0005777 PMID: 12453219|CGD_REF: CAL0080981 homozygous diploid, classical genetics null CAI-4 mating response: absent C. albicans orf19.469 ORF HST7 CAL0005777 PMID: 12453219|CGD_REF: CAL0080981 homozygous diploid, classical genetics null CAI-4 viable C. albicans orf19.469 ORF HST7 CAL0005777 PMID: 12453220|CGD_REF: CAL0080738 homozygous diploid, classical genetics null Other C. albicans viable C. albicans orf19.469 ORF HST7 CAL0005777 PMID: 12453220|CGD_REF: CAL0080738 homozygous diploid, classical genetics null Other C. albicans mating response: absent C. albicans orf19.469 ORF HST7 CAL0005777 PMID: 16467475|CGD_REF: CAL0115509 homozygous diploid, classical genetics null RM1000 resistance to chemicals: decreased Congo Red C. albicans orf19.469 ORF HST7 CAL0005777 PMID: 16467475|CGD_REF: CAL0115509 homozygous diploid, classical genetics null RM1000 resistance to chemicals: decreased Calcofluor White C. albicans orf19.469 ORF HST7 CAL0005777 PMID: 16467475|CGD_REF: CAL0115509 homozygous diploid, classical genetics null RM1000 protein/peptide modification: absent Cek1p is not phosphorylated Cek1p C. albicans orf19.469 ORF HST7 CAL0005777 PMID: 8917571|CGD_REF: CAL0081089 heterozygous diploid, classical genetics null CAI-4 virulence: normal mouse intravenous infection C. albicans orf19.469 ORF HST7 CAL0005777 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: abnormal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.469 ORF HST7 CAL0005777 PMID: 23856128|CGD_REF: CAL0000172540 homozygous diploid, classical genetics null BWP17 resistance to chemicals: decreased propolis C. albicans orf19.469 ORF HST7 CAL0005777 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.469 ORF HST7 CAL0005777 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.4690 ORF CAL0003849 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.4691 ORF MRV1 CAL0003851 PMID: 24281718|CGD_REF: CAL0000173710 homozygous diploid, classical genetics null BWP17 viable C. albicans orf19.4691 ORF MRV1 CAL0003851 PMID: 24610660|CGD_REF: CAL0000173793 homozygous diploid, classical genetics null BWP17 viable C. albicans orf19.4697 ORF MDN1 CAL0003858 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.4698 ORF PTC8 CAL0003860 PMID: 19049858|CGD_REF: CAL0121293 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.4698 ORF PTC8 CAL0003860 PMID: 19049858|CGD_REF: CAL0121293 homozygous diploid, classical genetics null RM1000 hyphal growth: absent Lee's, 10% serum, and Spider media C. albicans orf19.4698 ORF PTC8 CAL0003860 PMID: 21414038|CGD_REF: CAL0141808 homozygous diploid, classical genetics null BWP17 viable C. albicans orf19.4698 ORF PTC8 CAL0003860 PMID: 21414038|CGD_REF: CAL0141808 homozygous diploid, classical genetics null BWP17 biofilm formation: normal C. albicans orf19.4699 ORF CAL0003862 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.4704 ORF ARO1 CAL0004346 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.4704 ORF ARO1 CAL0004346 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient YPD medium C. albicans orf19.4704 ORF ARO1 CAL0004346 PMID: 21135205|CGD_REF: CAL0139967 heterozygous diploid, large-scale survey (large-scale identification of genes essential for virulence in mouse) repressible CAI-4 virulence: absent mouse intravenous infection C. albicans orf19.4705 ORF CAL0004347 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.4705 ORF CAL0004347 PMID: 21135205|CGD_REF: CAL0139967 heterozygous diploid, large-scale survey (large-scale identification of genes essential for virulence in mouse) repressible CAI-4 virulence: absent mouse intravenous infection C. albicans orf19.4707 ORF CAL0004352 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.4707 ORF CAL0004352 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.4707 ORF CAL0004352 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.4707 ORF CAL0004352 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.4707 ORF CAL0004352 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.4712 ORF FGR6-3 CAL0004368 PMID: 12773383|CGD_REF: CAL0087974 heterozygous diploid, classical genetics (haploinsufficient phenotype assay) null CAI-4 viable C. albicans orf19.4712 ORF FGR6-3 CAL0004368 PMID: 12773383|CGD_REF: CAL0087974 heterozygous diploid, classical genetics (haploinsufficient phenotype assay) null CAI-4 filamentous growth: increased solid Spider medium heterozygous transposon insertion C. albicans orf19.4715 ORF CAL0004372 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 invasive growth: decreased solid SLAD media C. albicans orf19.4718 ORF TRP5 CAL0004378 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.4718 ORF TRP5 CAL0004378 PMID: 21135205|CGD_REF: CAL0139967 heterozygous diploid, competitive growth (large-scale identification of genes essential for virulence in mouse) repressible CAI-4 virulence: normal mouse intravenous infection C. albicans orf19.4719 ORF CWH41 CAL0004381 PMID: 17933909|CGD_REF: CAL0118852 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased Calcofluor White C. albicans orf19.4719 ORF CWH41 CAL0004381 PMID: 17933909|CGD_REF: CAL0118852 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased sodium dodecyl sulfate C. albicans orf19.4719 ORF CWH41 CAL0004381 PMID: 17933909|CGD_REF: CAL0118852 homozygous diploid, classical genetics null Not recorded vegetative growth: decreased rate rich medium at 30 deg C C. albicans orf19.4719 ORF CWH41 CAL0004381 PMID: 17933909|CGD_REF: CAL0118852 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.4719 ORF CWH41 CAL0004381 PMID: 17933909|CGD_REF: CAL0118852 homozygous diploid, classical genetics null Not recorded cell size: increased C. albicans orf19.4719 ORF CWH41 CAL0004381 PMID: 17933909|CGD_REF: CAL0118852 homozygous diploid, classical genetics null Not recorded chemical compound accumulation: decreased mannan decreased cell wall mannan C. albicans orf19.4719 ORF CWH41 CAL0004381 PMID: 17933909|CGD_REF: CAL0118852 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased Congo Red C. albicans orf19.4719 ORF CWH41 CAL0004381 PMID: 17933909|CGD_REF: CAL0118852 homozygous diploid, classical genetics null CAI-4 filamentous growth: absent solid Spider medium C. albicans orf19.4719 ORF CWH41 CAL0004381 PMID: 17933909|CGD_REF: CAL0118852 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased Hygromycin B C. albicans orf19.4719 ORF CWH41 CAL0004381 PMID: 17933909|CGD_REF: CAL0118852 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased tunicamycin C. albicans orf19.4719 ORF CWH41 CAL0004381 PMID: 17933909|CGD_REF: CAL0118852 homozygous diploid, classical genetics null Not recorded chemical compound accumulation: decreased glucan decreased cell wall glucan C. albicans orf19.4719 ORF CWH41 CAL0004381 PMID: 17933909|CGD_REF: CAL0118852 homozygous diploid, classical genetics null Not recorded virulence: decreased mouse intravenous infection C. albicans orf19.4720 ORF CTR2 CAL0004393 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: decreased growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.4720 ORF CTR2 CAL0004393 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: abnormal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.4720 ORF CTR2 CAL0004393 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.4720 ORF CTR2 CAL0004393 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.4722 ORF RTG1 CAL0004395 PMID: 20041210|CGD_REF: CAL0124764 homozygous diploid, systematic mutation set null SN152 resistance to chemicals: increased rapamycin strongly resistant C. albicans orf19.4722 ORF RTG1 CAL0004395 PMID: 23526879|CGD_REF: CAL0000158852 homozygous diploid, classical genetics null SN152 viable C. albicans orf19.4722 ORF RTG1 CAL0004395 PMID: 23526879|CGD_REF: CAL0000158852 homozygous diploid, classical genetics null SN152 virulence: decreased significant defect in GI tract colonization mouse gastrointestinal tract infection C. albicans orf19.4722 ORF RTG1 CAL0004395 PMID: 23526879|CGD_REF: CAL0000158852 homozygous diploid, classical genetics null SN152 virulence: decreased mouse intravenous infection C. albicans orf19.4723 ORF FAD1 CAL0004396 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.4724 ORF CAL0004398 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.4725 ORF SWI6 CAL0004400 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.4725 ORF SWI6 CAL0004400 PMID: 21257795|CGD_REF: CAL0141410 homozygous diploid, classical genetics null BWP17 viable C. albicans orf19.4725 ORF SWI6 CAL0004400 PMID: 21257795|CGD_REF: CAL0141410 homozygous diploid, classical genetics null BWP17 cell size: increased C. albicans orf19.4725 ORF SWI6 CAL0004400 PMID: 21257795|CGD_REF: CAL0141410 homozygous diploid, classical genetics null BWP17 cell shape: abnormal elongated cells C. albicans orf19.4725 ORF SWI6 CAL0004400 PMID: 20865172|CGD_REF: CAL0126252 homozygous diploid, classical genetics null SN95 resistance to chemicals: decreased fluconazole C. albicans orf19.4725 ORF SWI6 CAL0004400 PMID: 20865172|CGD_REF: CAL0126252 homozygous diploid, classical genetics null SN95 resistance to chemicals: decreased fenpropimorph C. albicans orf19.4725 ORF SWI6 CAL0004400 PMID: 20865172|CGD_REF: CAL0126252 homozygous diploid, classical genetics null SN95 resistance to chemicals: decreased terbinafine C. albicans orf19.4726 ORF CAL0004401 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.4728 ORF CAL0004407 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.473 ORF TPO4 CAL0005793 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.4731 ORF CAL0004421 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.4732 ORF SEC24 CAL0004422 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.4733 ORF YMC2 CAL0004423 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.4735 ORF CAL0004427 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.4736 ORF CAL0004429 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.4736 ORF CAL0004429 PMID: 23856128|CGD_REF: CAL0000172540 homozygous diploid, classical genetics null BWP17 resistance to chemicals: decreased propolis C. albicans orf19.4737 ORF TPO3 CAL0004432 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, competitive growth (haploinsufficient phenotype assay, barcode deletion set) null SC5314 resistance to chemicals: decreased 5-fluorouracil C. albicans orf19.4737 ORF TPO3 CAL0004432 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, competitive growth (haploinsufficient phenotype assay, barcode deletion set) null SC5314 resistance to chemicals: decreased tubercidin C. albicans orf19.4737 ORF TPO3 CAL0004432 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, competitive growth (haploinsufficient phenotype assay, barcode deletion set) null SC5314 resistance to chemicals: decreased flucytosine C. albicans orf19.4737 ORF TPO3 CAL0004432 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.4737 ORF TPO3 CAL0004432 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 invasive growth: decreased solid SLAD media C. albicans orf19.4738 ORF CAL0004434 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.4738 ORF CAL0004434 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.4738 ORF CAL0004434 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.4738 ORF CAL0004434 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: decreased rate liquid synthetic complete medium C. albicans orf19.4738 ORF CAL0004434 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.4739 ORF MSS116 CAL0004436 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.474 ORF CAL0005795 PMID: 21135205|CGD_REF: CAL0139967 heterozygous diploid, large-scale survey (large-scale identification of genes essential for virulence in mouse) repressible CAI-4 virulence: absent mouse intravenous infection C. albicans orf19.4742 ORF CAL0004447 PMID: 20402797|CGD_REF: CAL0125391 homozygous diploid, classical genetics null Other C. albicans viable C. albicans orf19.4743 ORF AFG1 CAL0004449 PMID: 14663094|CGD_REF: CAL0080633 homozygous diploid, systematic mutation set (homozygous insertion mutants generated with URA3-ARG4-URA3 (UAU1) cassette) null BWP17 viable C. albicans orf19.4744 ORF CAL0004451 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.4744 ORF CAL0004451 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.4744 ORF CAL0004451 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.4744 ORF CAL0004451 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.4744 ORF CAL0004451 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.4746 ORF JIP5 CAL0004454 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.4746 ORF JIP5 CAL0004454 PMID: 14663094|CGD_REF: CAL0080633 homozygous diploid, systematic mutation set (homozygous insertion mutants generated with URA3-ARG4-URA3 (UAU1) cassette) null BWP17 viable C. albicans orf19.4747 ORF HEM14 CAL0004457 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.4750 ORF CAL0004474 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 invasive growth: decreased solid SLAD media C. albicans orf19.4752 ORF MSN4 CAL0004476 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.4752 ORF MSN4 CAL0004476 PMID: 15964282|CGD_REF: CAL0114274 homozygous diploid, systematic mutation set (split-marker transposon insertion strategy to disrupt both alleles) null BWP17 viable C. albicans orf19.4752 ORF MSN4 CAL0004476 PMID: 19463063|CGD_REF: CAL0123630 homozygous diploid, systematic mutation set (split-marker transposon insertion strategy to disrupt both alleles) null BWP17 viable C. albicans orf19.4752 ORF MSN4 CAL0004476 PMID: 15470239|CGD_REF: CAL0082146 homozygous diploid, classical genetics null Not recorded viable no apparent phenotype C. albicans orf19.4752 ORF MSN4 CAL0004476 PMID: 15470239|CGD_REF: CAL0082146 heterozygous diploid, classical genetics overexpression Not recorded viable no apparent stress-related phenotype C. albicans orf19.4752 ORF MSN4 CAL0004476 PMID: 15964282|CGD_REF: CAL0114274 homozygous diploid, systematic mutation set (split-marker transposon insertion strategy to disrupt both alleles) null BWP17 biofilm formation: normal C. albicans orf19.4752 ORF MSN4 CAL0004476 PMID: 19463063|CGD_REF: CAL0123630 homozygous diploid, systematic mutation set (split-marker transposon insertion strategy to disrupt both alleles) null BWP17 virulence: normal Toll mutant D. melanogaster invasive infection insect infection C. albicans orf19.4752 ORF MSN4 CAL0004476 PMID: 19463063|CGD_REF: CAL0123630 homozygous diploid, classical genetics null BWP17 virulence: normal BALB/c mice mouse intravenous infection C. albicans orf19.4752 ORF MSN4 CAL0004476 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient SC medium C. albicans orf19.4752 ORF MSN4 CAL0004476 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient SLAD medium C. albicans orf19.4753 ORF PFK26 CAL0004477 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.4755 ORF KEX2 CAL0004481 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.4755 ORF KEX2 CAL0004481 PMID: 14507372|CGD_REF: CAL0088818 heterozygous diploid, large-scale survey (large-scale identification of essential genes by gene replacement and conditional expression (GRACE) method) repressible CAI-4 viable one allele is deleted and the other is placed under repressible Tet promoter C. albicans orf19.4755 ORF KEX2 CAL0004481 PMID: 12419804|CGD_REF: CAL0081433 heterozygous diploid, classical genetics null Not recorded viable C. albicans orf19.4755 ORF KEX2 CAL0004481 PMID: 12419804|CGD_REF: CAL0081433 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.4755 ORF KEX2 CAL0004481 PMID: 9360967|CGD_REF: CAL0081464 heterozygous diploid, classical genetics null Not recorded viable C. albicans orf19.4755 ORF KEX2 CAL0004481 PMID: 9360967|CGD_REF: CAL0081464 homozygous diploid, classical genetics null Not recorded protein/peptide modification: absent Sap2p is not processed Sap2p C. albicans orf19.4755 ORF KEX2 CAL0004481 PMID: 12419804|CGD_REF: CAL0081433 homozygous diploid, classical genetics null CAI-4 hyphal growth: abnormal abolished hyphal induction upon phagocytosis by macrophage C. albicans orf19.4755 ORF KEX2 CAL0004481 PMID: 9360967|CGD_REF: CAL0081464 homozygous diploid, classical genetics null CAI-4 hyphal growth: absent liquid RPMI 1640 or YEPD plus serum at 37 deg C C. albicans orf19.4755 ORF KEX2 CAL0004481 PMID: 9360967|CGD_REF: CAL0081464 heterozygous diploid, classical genetics null CAI-4 hyphal growth: normal liquid RPMI 1640 or YEPD plus serum at 37 deg C C. albicans orf19.4755 ORF KEX2 CAL0004481 PMID: 12419804|CGD_REF: CAL0081433 homozygous diploid, classical genetics null Not recorded cell shape: abnormal embedded in agar cells are elongated and aberrantly shaped C. albicans orf19.4755 ORF KEX2 CAL0004481 PMID: 12419804|CGD_REF: CAL0081433 homozygous diploid, classical genetics null CAI-4 invasive growth: absent embedded in agar C. albicans orf19.4755 ORF KEX2 CAL0004481 PMID: 9360967|CGD_REF: CAL0081464 homozygous diploid, classical genetics null Not recorded chitin deposition: abnormal liquid RPMI 1640 or YEPD plus serum media at 37 deg C C. albicans orf19.4755 ORF KEX2 CAL0004481 PMID: 9360967|CGD_REF: CAL0081464 homozygous diploid, classical genetics null Not recorded protein secretion: decreased decreased secreted aspartyl protease activity C. albicans orf19.4755 ORF KEX2 CAL0004481 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: decreased growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.4755 ORF KEX2 CAL0004481 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, classical genetics null SN152 germ tube formation: decreased serum-containing medium C. albicans orf19.4755 ORF KEX2 CAL0004481 PMID: 12419804|CGD_REF: CAL0081433 homozygous diploid, classical genetics null Not recorded virulence: decreased macrophage culture decreased capacity to lyse macrophages in vitro model of infection C. albicans orf19.4755 ORF KEX2 CAL0004481 PMID: 12419804|CGD_REF: CAL0081433 homozygous diploid, classical genetics null Not recorded virulence: decreased exhibits decreased kidney colonization mouse intravenous infection C. albicans orf19.4755 ORF KEX2 CAL0004481 PMID: 12419804|CGD_REF: CAL0081433 heterozygous diploid, classical genetics null Not recorded virulence: decreased virulence is intermediate between that of the homozygous null mutant and wild type mouse intravenous infection C. albicans orf19.4755 ORF KEX2 CAL0004481 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.4755 ORF KEX2 CAL0004481 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.4757 ORF NAR1 CAL0004486 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.4757 ORF NAR1 CAL0004486 PMID: 14507372|CGD_REF: CAL0088818 heterozygous diploid, large-scale survey (large-scale identification of essential genes by gene replacement and conditional expression (GRACE) method) repressible CAI-4 inviable one allele is deleted and the other is placed under repressible Tet promoter C. albicans orf19.4758 ORF CAL0004489 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.4758 ORF CAL0004489 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: decreased growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.4758 ORF CAL0004489 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: decreased rate liquid synthetic complete medium C. albicans orf19.4758 ORF CAL0004489 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.4760 ORF CAL0004512 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.4761 ORF HST1 CAL0004513 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.4761 ORF HST1 CAL0004513 PMID: 19555456|CGD_REF: CAL0123821 homozygous diploid, classical genetics null Not recorded phenotypic switching: decreased MTLa/MTLa background opaque-to-white switching C. albicans orf19.4764 ORF CAL0004517 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient YPD medium C. albicans orf19.4765 ORF PGA6 CAL0004519 PMID: 15870470|CGD_REF: CAL0082507 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.4765 ORF PGA6 CAL0004519 PMID: 18765290|CGD_REF: CAL0119430 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.4765 ORF PGA6 CAL0004519 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.4765 ORF PGA6 CAL0004519 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.4765 ORF PGA6 CAL0004519 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.4765 ORF PGA6 CAL0004519 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.4766 ORF ARG81 CAL0004520 PMID: 15964282|CGD_REF: CAL0114274 homozygous diploid, systematic mutation set (split-marker transposon insertion strategy to disrupt both alleles) null BWP17 viable C. albicans orf19.4766 ORF ARG81 CAL0004520 PMID: 19463063|CGD_REF: CAL0123630 homozygous diploid, systematic mutation set (split-marker transposon insertion strategy to disrupt both alleles) null BWP17 viable C. albicans orf19.4766 ORF ARG81 CAL0004520 PMID: 20041210|CGD_REF: CAL0124764 homozygous diploid, systematic mutation set null SN152 resistance to chemicals: decreased rapamycin strongly sensitive C. albicans orf19.4766 ORF ARG81 CAL0004520 PMID: 15964282|CGD_REF: CAL0114274 homozygous diploid, systematic mutation set (split-marker transposon insertion strategy to disrupt both alleles) null BWP17 biofilm formation: normal C. albicans orf19.4766 ORF ARG81 CAL0004520 PMID: 20041210|CGD_REF: CAL0124764 homozygous diploid, systematic mutation set null SN152 resistance to chemicals: decreased caffeine strongly sensitive C. albicans orf19.4766 ORF ARG81 CAL0004520 PMID: 22073120|CGD_REF: CAL0000143592 homozygous diploid, classical genetics null BWP17 viable C. albicans orf19.4766 ORF ARG81 CAL0004520 PMID: 22073120|CGD_REF: CAL0000143592 homozygous diploid, classical genetics null BWP17 hyphal growth: increased C. albicans orf19.4766 ORF ARG81 CAL0004520 PMID: 22359502|CGD_REF: CAL0000144048 homozygous diploid, classical genetics null BWP17 adhesion: decreased insertion mutant, independent BWP17 and SN152 deletion mutants also tested C. albicans orf19.4766 ORF ARG81 CAL0004520 PMID: 22359502|CGD_REF: CAL0000144048 homozygous diploid, classical genetics null BWP17 viable insertion mutant, independent BWP17 and SN152 deletion mutants also tested C. albicans orf19.4766 ORF ARG81 CAL0004520 PMID: 19463063|CGD_REF: CAL0123630 homozygous diploid, systematic mutation set (split-marker transposon insertion strategy to disrupt both alleles) null BWP17 virulence: normal Toll mutant D. melanogaster invasive infection insect infection C. albicans orf19.4767 ORF ZCF28 CAL0004522 PMID: 17555439|CGD_REF: CAL0117968 homozygous diploid, classical genetics null Not recorded survival rate in stationary phase: decreased C. albicans orf19.4767 ORF ZCF28 CAL0004522 PMID: 15964282|CGD_REF: CAL0114274 homozygous diploid, systematic mutation set (split-marker transposon insertion strategy to disrupt both alleles) null BWP17 viable C. albicans orf19.4767 ORF ZCF28 CAL0004522 PMID: 15964282|CGD_REF: CAL0114274 homozygous diploid, systematic mutation set (split-marker transposon insertion strategy to disrupt both alleles) null BWP17 biofilm formation: normal C. albicans orf19.4767 ORF ZCF28 CAL0004522 PMID: 22359502|CGD_REF: CAL0000144048 homozygous diploid, classical genetics null BWP17 adhesion: decreased insertion mutant, independent BWP17 and SN152 deletion mutants also tested C. albicans orf19.4767 ORF ZCF28 CAL0004522 PMID: 22359502|CGD_REF: CAL0000144048 homozygous diploid, classical genetics null BWP17 viable insertion mutant, independent BWP17 and SN152 deletion mutants also tested C. albicans orf19.4768 ORF CAL0004524 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.4769 ORF IPT1 CAL0004527 PMID: 16048959|CGD_REF: CAL0114430 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased ketoconazole C. albicans orf19.4769 ORF IPT1 CAL0004527 PMID: 16246085|CGD_REF: CAL0114864 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased ketoconazole C. albicans orf19.4769 ORF IPT1 CAL0004527 PMID: 16048959|CGD_REF: CAL0114430 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased itraconazole C. albicans orf19.4769 ORF IPT1 CAL0004527 PMID: 16048959|CGD_REF: CAL0114430 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.4769 ORF IPT1 CAL0004527 PMID: 16246085|CGD_REF: CAL0114864 heterozygous diploid, classical genetics null Not recorded viable C. albicans orf19.4769 ORF IPT1 CAL0004527 PMID: 16246085|CGD_REF: CAL0114864 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.4769 ORF IPT1 CAL0004527 PMID: 16246085|CGD_REF: CAL0114864 homozygous diploid, classical genetics null Not recorded protein/peptide distribution: abnormal decreased cell-surface localization of Cdr1p Cdr1p C. albicans orf19.4769 ORF IPT1 CAL0004527 PMID: 16246085|CGD_REF: CAL0114864 homozygous diploid, classical genetics null CAF2-1 hyphal growth: decreased solid Spider or liquid GlcNAc plus serum media C. albicans orf19.4769 ORF IPT1 CAL0004527 PMID: 16048959|CGD_REF: CAL0114430 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased 4-nitroquinoline N-oxide C. albicans orf19.4769 ORF IPT1 CAL0004527 PMID: 16246085|CGD_REF: CAL0114864 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased 4-nitroquinoline N-oxide C. albicans orf19.4769 ORF IPT1 CAL0004527 PMID: 16048959|CGD_REF: CAL0114430 homozygous diploid, classical genetics null Not recorded resistance to chemicals: increased amphotericin B C. albicans orf19.4769 ORF IPT1 CAL0004527 PMID: 16048959|CGD_REF: CAL0114430 homozygous diploid, classical genetics null Not recorded resistance to chemicals: increased nystatin C. albicans orf19.4769 ORF IPT1 CAL0004527 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, competitive growth (haploinsufficient phenotype assay, barcode deletion set) null SC5314 resistance to chemicals: decreased Aureobasidin A C. albicans orf19.4769 ORF IPT1 CAL0004527 PMID: 16246085|CGD_REF: CAL0114864 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased sulphomethuron methyl sensitivity is probable result of Cdr1p mislocalization C. albicans orf19.4769 ORF IPT1 CAL0004527 PMID: 16048959|CGD_REF: CAL0114430 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased terbinafine C. albicans orf19.4769 ORF IPT1 CAL0004527 PMID: 16246085|CGD_REF: CAL0114864 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased terbinafine C. albicans orf19.4769 ORF IPT1 CAL0004527 PMID: 16048959|CGD_REF: CAL0114430 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased 1,10-phenanthroline C. albicans orf19.4769 ORF IPT1 CAL0004527 PMID: 16246085|CGD_REF: CAL0114864 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased 1,10-phenanthroline C. albicans orf19.4769 ORF IPT1 CAL0004527 PMID: 16048959|CGD_REF: CAL0114430 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased fluconazole C. albicans orf19.4769 ORF IPT1 CAL0004527 PMID: 16246085|CGD_REF: CAL0114864 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased fluconazole C. albicans orf19.4769 ORF IPT1 CAL0004527 PMID: 21091155|CGD_REF: CAL0139891 homozygous diploid, classical genetics null CAI-4 induction of host response: decreased decreased TLR2, TLR4, TLR6, and TLR9 gene expression in the epithelial cells C. albicans orf19.4769 ORF IPT1 CAL0004527 PMID: 21091155|CGD_REF: CAL0139891 homozygous diploid, classical genetics null CAI-4 induction of host response: decreased mutant fails to induce host antimicrobial peptides, HBD-2 and HBD-3 C. albicans orf19.4769 ORF IPT1 CAL0004527 PMID: 21903752|CGD_REF: CAL0000142904 homozygous diploid, classical genetics null CAI-4 biofilm formation: absent C. albicans orf19.4769 ORF IPT1 CAL0004527 PMID: 21091155|CGD_REF: CAL0139891 homozygous diploid, classical genetics null ipt1::hisG-URA3-hisG/ipt1::hisG CAI-4 adhesion: decreased reduced adherence to human gingival epithelial cells C. albicans orf19.4769 ORF IPT1 CAL0004527 PMID: 21091155|CGD_REF: CAL0139891 homozygous diploid, classical genetics null ipt1::hisG-URA3-hisG/ipt1::hisG CAI-4 hyphal growth: decreased C. albicans orf19.4771 ORF CAL0004545 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.4771 ORF CAL0004545 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.4771 ORF CAL0004545 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.4771 ORF CAL0004545 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.4771 ORF CAL0004545 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.4772 ORF SSU81 CAL0004546 PMID: 19563901|CGD_REF: CAL0123856 homozygous diploid, classical genetics null Not recorded flocculation: increased C. albicans orf19.4772 ORF SSU81 CAL0004546 PMID: 19542310|CGD_REF: CAL0123805 homozygous diploid, classical genetics null Not recorded resistance to enzymatic treatment: decreased zymolyase C. albicans orf19.4772 ORF SSU81 CAL0004546 PMID: 16287872|CGD_REF: CAL0115040 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased Calcofluor White C. albicans orf19.4772 ORF SSU81 CAL0004546 PMID: 19563901|CGD_REF: CAL0123856 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased Calcofluor White C. albicans orf19.4772 ORF SSU81 CAL0004546 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.4772 ORF SSU81 CAL0004546 PMID: 16287872|CGD_REF: CAL0115040 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.4772 ORF SSU81 CAL0004546 PMID: 16287872|CGD_REF: CAL0115040 homozygous diploid, classical genetics null Not recorded hyphal growth: absent hyphal growth-inducing conditions C. albicans orf19.4772 ORF SSU81 CAL0004546 PMID: 16287872|CGD_REF: CAL0115040 homozygous diploid, classical genetics null Not recorded ionic stress resistance: decreased sodium chloride C. albicans orf19.4772 ORF SSU81 CAL0004546 PMID: 16287872|CGD_REF: CAL0115040 homozygous diploid, classical genetics null Not recorded osmotic stress resistance: decreased glucitol C. albicans orf19.4772 ORF SSU81 CAL0004546 PMID: 16287872|CGD_REF: CAL0115040 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased Congo Red C. albicans orf19.4772 ORF SSU81 CAL0004546 PMID: 19563901|CGD_REF: CAL0123856 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased Congo Red C. albicans orf19.4772 ORF SSU81 CAL0004546 PMID: 19542310|CGD_REF: CAL0123805 homozygous diploid, classical genetics null RM1000 filamentous growth: decreased hypoxic conditions C. albicans orf19.4772 ORF SSU81 CAL0004546 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.4772 ORF SSU81 CAL0004546 PMID: 21375589|CGD_REF: CAL0141772 homozygous diploid, classical genetics null CAF2-1 resistance to chemicals: decreased tunicamycin C. albicans orf19.4772 ORF SSU81 CAL0004546 PMID: 21375589|CGD_REF: CAL0141772 homozygous diploid, classical genetics null CAF2-1 resistance to chemicals: decreased caspofungin C. albicans orf19.4772 ORF SSU81 CAL0004546 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: abnormal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.4772 ORF SSU81 CAL0004546 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.4772 ORF SSU81 CAL0004546 PMID: 20402797|CGD_REF: CAL0125391 homozygous diploid, classical genetics null Other C. albicans viable C. albicans orf19.4772 ORF SSU81 CAL0004546 PMID: 20384695|CGD_REF: CAL0125373 homozygous diploid, classical genetics null BWP17 resistance to chemicals: decreased Congo Red (200 microgram/ml) C. albicans orf19.4772 ORF SSU81 CAL0004546 PMID: 20384695|CGD_REF: CAL0125373 homozygous diploid, classical genetics null BWP17 invasive growth: delayed Congo Red (200 microgram/ml) embedded agar conditions C. albicans orf19.4772 ORF SSU81 CAL0004546 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.4772 ORF SSU81 CAL0004546 PMID: 21135205|CGD_REF: CAL0139967 heterozygous diploid, competitive growth (large-scale identification of genes essential for virulence in mouse) repressible CAI-4 virulence: normal mouse intravenous infection C. albicans orf19.4773 ORF AOX2 CAL0004548 PMID: 11368790|CGD_REF: CAL0080749 homozygous diploid, classical genetics null Not recorded respiratory growth: decreased cyanide-resistant respiration is severely reduced C. albicans orf19.4773 ORF AOX2 CAL0004548 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.4773 ORF AOX2 CAL0004548 PMID: 14507372|CGD_REF: CAL0088818 heterozygous diploid, large-scale survey (large-scale identification of essential genes by gene replacement and conditional expression (GRACE) method) repressible CAI-4 viable one allele is deleted and the other is placed under repressible Tet promoter C. albicans orf19.4773 ORF AOX2 CAL0004548 PMID: 11368790|CGD_REF: CAL0080749 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.4773 ORF AOX2 CAL0004548 PMID: 11368790|CGD_REF: CAL0080749 homozygous diploid, classical genetics null Not recorded hyphal growth: normal C. albicans orf19.4773 ORF AOX2 CAL0004548 PMID: 11368790|CGD_REF: CAL0080749 homozygous diploid, classical genetics null Not recorded virulence: normal mouse intravenous infection C. albicans orf19.4773 ORF AOX2 CAL0004548 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient YPD medium C. albicans orf19.4774 ORF AOX1 CAL0004550 PMID: 11368790|CGD_REF: CAL0080749 homozygous diploid, classical genetics null Not recorded respiratory growth: decreased cyanide-resistant respiration is severely reduced C. albicans orf19.4774 ORF AOX1 CAL0004550 PMID: 10383980|CGD_REF: CAL0080748 homozygous diploid, classical genetics null Not recorded respiratory growth: decreased C. albicans orf19.4774 ORF AOX1 CAL0004550 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.4774 ORF AOX1 CAL0004550 PMID: 10383980|CGD_REF: CAL0080748 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.4774 ORF AOX1 CAL0004550 PMID: 11368790|CGD_REF: CAL0080749 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.4774 ORF AOX1 CAL0004550 PMID: 11368790|CGD_REF: CAL0080749 homozygous diploid, classical genetics null Not recorded hyphal growth: normal C. albicans orf19.4774 ORF AOX1 CAL0004550 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.4774 ORF AOX1 CAL0004550 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.4774 ORF AOX1 CAL0004550 PMID: 11368790|CGD_REF: CAL0080749 homozygous diploid, classical genetics null Not recorded virulence: normal mouse intravenous infection C. albicans orf19.4774 ORF AOX1 CAL0004550 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient YPD medium C. albicans orf19.4774 ORF AOX1 CAL0004550 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.4774 ORF AOX1 CAL0004550 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient SLAD medium C. albicans orf19.4774 ORF AOX1 CAL0004550 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.4775 ORF CTA8 CAL0004552 PMID: 19818013|CGD_REF: CAL0124404 heterozygous diploid, classical genetics repressible Not recorded thermotolerance: decreased exposure to 30-45 deg C for 30 min decreased viability after heat shock C. albicans orf19.4775 ORF CTA8 CAL0004552 PMID: 19818013|CGD_REF: CAL0124404 homozygous diploid, classical genetics null Other C. albicans inviable C. albicans orf19.4775 ORF CTA8 CAL0004552 PMID: 19818013|CGD_REF: CAL0124404 heterozygous diploid, classical genetics repressible Other C. albicans thermotolerance: decreased exposure to elevated temperature (30-45 deg C heat shock for 30 min) decreased viability after heat shock C. albicans orf19.4775 ORF CTA8 CAL0004552 PMID: 19818013|CGD_REF: CAL0124404 homozygous diploid, classical genetics null Not recorded inviable C. albicans orf19.4775 ORF CTA8 CAL0004552 PMID: 20817114|CGD_REF: CAL0126218 homozygous diploid, classical genetics reduction of function cta8-delta-CE2 CAI-4 heat sensitivity: increased C. albicans orf19.4775 ORF CTA8 CAL0004552 PMID: 20817114|CGD_REF: CAL0126218 homozygous diploid, classical genetics reduction of function cta8-CE2t (truncated CE2 domain) CAI-4 virulence: decreased mouse intravenous infection C. albicans orf19.4776 ORF LYS143 CAL0004554 PMID: 15964282|CGD_REF: CAL0114274 homozygous diploid, systematic mutation set (split-marker transposon insertion strategy to disrupt both alleles) null BWP17 viable C. albicans orf19.4776 ORF LYS143 CAL0004554 PMID: 15964282|CGD_REF: CAL0114274 homozygous diploid, systematic mutation set (split-marker transposon insertion strategy to disrupt both alleles) null BWP17 biofilm formation: normal C. albicans orf19.4778 ORF LYS142 CAL0004560 PMID: 17555439|CGD_REF: CAL0117968 homozygous diploid, classical genetics null Not recorded survival rate in stationary phase: decreased C. albicans orf19.4778 ORF LYS142 CAL0004560 PMID: 15964282|CGD_REF: CAL0114274 homozygous diploid, systematic mutation set (split-marker transposon insertion strategy to disrupt both alleles) null BWP17 viable C. albicans orf19.4778 ORF LYS142 CAL0004560 PMID: 15964282|CGD_REF: CAL0114274 homozygous diploid, systematic mutation set (split-marker transposon insertion strategy to disrupt both alleles) null BWP17 biofilm formation: normal C. albicans orf19.4778 ORF LYS142 CAL0004560 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient YPD medium C. albicans orf19.4778 ORF LYS142 CAL0004560 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient SLAD medium C. albicans orf19.4779 ORF CAL0004562 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.4780 ORF CAL0004582 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.4781 ORF GRP1 CAL0004583 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.4783 ORF CAL0004585 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.4783 ORF CAL0004585 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.4783 ORF CAL0004585 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.4783 ORF CAL0004585 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.4783 ORF CAL0004585 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.4784 ORF CRP1 CAL0004587 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.4784 ORF CRP1 CAL0004587 PMID: 14663094|CGD_REF: CAL0080633 homozygous diploid, systematic mutation set (homozygous insertion mutants generated with URA3-ARG4-URA3 (UAU1) cassette) null BWP17 viable C. albicans orf19.4784 ORF CRP1 CAL0004587 PMID: 10737803|CGD_REF: CAL0081080 heterozygous diploid, classical genetics null crp1::hisG-URA3-hisG Other C. albicans metal resistance: normal copper C. albicans orf19.4784 ORF CRP1 CAL0004587 PMID: 10737803|CGD_REF: CAL0081080 heterozygous diploid, classical genetics null crp1::hisG-URA3-hisG Other C. albicans viable C. albicans orf19.4784 ORF CRP1 CAL0004587 PMID: 10940034|CGD_REF: CAL0081081 heterozygous diploid, classical genetics null crp1::hisG-URA3-hisG/CRP1 CAI-4 metal resistance: decreased copper C. albicans orf19.4784 ORF CRP1 CAL0004587 PMID: 10940034|CGD_REF: CAL0081081 heterozygous diploid, classical genetics null crp1::hisG-URA3-hisG/CRP1 CAI-4 viable C. albicans orf19.4784 ORF CRP1 CAL0004587 PMID: 10737803|CGD_REF: CAL0081080 homozygous diploid, classical genetics null crp1::hisG-URA3-hisG/crp1::hisG Other C. albicans metal resistance: normal cadmium C. albicans orf19.4784 ORF CRP1 CAL0004587 PMID: 10940034|CGD_REF: CAL0081081 homozygous diploid, classical genetics null crp1::hisG-URA3-hisG/crp1::hisG CAI-4 metal resistance: decreased cadmium C. albicans orf19.4784 ORF CRP1 CAL0004587 PMID: 10737803|CGD_REF: CAL0081080 homozygous diploid, classical genetics null crp1::hisG-URA3-hisG/crp1::hisG Other C. albicans metal resistance: normal zinc C. albicans orf19.4784 ORF CRP1 CAL0004587 PMID: 10940034|CGD_REF: CAL0081081 homozygous diploid, classical genetics null crp1::hisG-URA3-hisG/crp1::hisG CAI-4 metal resistance: normal zinc C. albicans orf19.4784 ORF CRP1 CAL0004587 PMID: 10737803|CGD_REF: CAL0081080 homozygous diploid, classical genetics null crp1::hisG-URA3-hisG/crp1::hisG Other C. albicans chemical compound accumulation: increased copper C. albicans orf19.4784 ORF CRP1 CAL0004587 PMID: 10737803|CGD_REF: CAL0081080 homozygous diploid, classical genetics null crp1::hisG-URA3-hisG/crp1::hisG Other C. albicans metal resistance: decreased copper C. albicans orf19.4784 ORF CRP1 CAL0004587 PMID: 10737803|CGD_REF: CAL0081080 homozygous diploid, classical genetics null crp1::hisG-URA3-hisG/crp1::hisG Other C. albicans metal resistance: normal silver C. albicans orf19.4784 ORF CRP1 CAL0004587 PMID: 10940034|CGD_REF: CAL0081081 homozygous diploid, classical genetics null crp1::hisG-URA3-hisG/crp1::hisG CAI-4 metal resistance: decreased silver C. albicans orf19.4784 ORF CRP1 CAL0004587 PMID: 10737803|CGD_REF: CAL0081080 homozygous diploid, classical genetics null crp1::hisG-URA3-hisG/crp1::hisG Other C. albicans viable C. albicans orf19.4784 ORF CRP1 CAL0004587 PMID: 10940034|CGD_REF: CAL0081081 homozygous diploid, classical genetics null crp1::hisG-URA3-hisG/crp1::hisG CAI-4 viable C. albicans orf19.4784 ORF CRP1 CAL0004587 PMID: 10737803|CGD_REF: CAL0081080 homozygous diploid, classical genetics null crp1::hisG-URA3-hisG/crp1::hisG Other C. albicans virulence: decreased growth abolished under conditions that simulate human digestive tract C. albicans orf19.4785 ORF PTC1 CAL0004589 PMID: 18708562|CGD_REF: CAL0119375 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.4785 ORF PTC1 CAL0004589 PMID: 18708562|CGD_REF: CAL0119375 homozygous diploid, classical genetics null CAI-4 hyphal growth: decreased serum-containing medium C. albicans orf19.4785 ORF PTC1 CAL0004589 PMID: 18708562|CGD_REF: CAL0119375 homozygous diploid, classical genetics null Not recorded protein secretion: decreased decreased extracellular protease activity C. albicans orf19.4785 ORF PTC1 CAL0004589 PMID: 18708562|CGD_REF: CAL0119375 homozygous diploid, classical genetics null Not recorded resistance to chemicals: increased Congo Red C. albicans orf19.4785 ORF PTC1 CAL0004589 PMID: 18708562|CGD_REF: CAL0119375 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased micafungin C. albicans orf19.4785 ORF PTC1 CAL0004589 PMID: 18708562|CGD_REF: CAL0119375 homozygous diploid, classical genetics null Not recorded resistance to chemicals: increased terbinafine C. albicans orf19.4785 ORF PTC1 CAL0004589 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: increased growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.4785 ORF PTC1 CAL0004589 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: abnormal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.4785 ORF PTC1 CAL0004589 PMID: 18708562|CGD_REF: CAL0119375 homozygous diploid, classical genetics null Not recorded virulence: decreased insect infection C. albicans orf19.4785 ORF PTC1 CAL0004589 PMID: 18708562|CGD_REF: CAL0119375 homozygous diploid, classical genetics null Not recorded virulence: decreased mouse intravenous infection C. albicans orf19.4785 ORF PTC1 CAL0004589 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.4785 ORF PTC1 CAL0004589 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.4786 ORF FGR43 CAL0004591 PMID: 12773383|CGD_REF: CAL0087974 heterozygous diploid, classical genetics (haploinsufficient phenotype assay) null CAI-4 viable heterozygous transposon insertion C. albicans orf19.4787 ORF CAL0004593 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.4788 ORF ARG5,6 CAL0004595 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.4788 ORF ARG5,6 CAL0004595 PMID: 10074081|CGD_REF: CAL0080678 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.4788 ORF ARG5,6 CAL0004595 PMID: 9043106|CGD_REF: CAL0080776 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.4788 ORF ARG5,6 CAL0004595 PMID: 10620776|CGD_REF: CAL0081775 homozygous diploid, classical genetics null arg5::URA3-dpl200 CAI-4 auxotrophy arginine C. albicans orf19.4788 ORF ARG5,6 CAL0004595 PMID: 10620776|CGD_REF: CAL0081775 heterozygous diploid, classical genetics null arg5::URA3-dpl200 CAI-4 viable C. albicans orf19.4788 ORF ARG5,6 CAL0004595 PMID: 10620776|CGD_REF: CAL0081775 homozygous diploid, classical genetics null arg5::URA3-dpl200 CAI-4 viable C. albicans orf19.4788 ORF ARG5,6 CAL0004595 PMID: 14507372|CGD_REF: CAL0088818 heterozygous diploid, large-scale survey (large-scale identification of essential genes by gene replacement and conditional expression (GRACE) method) repressible CAI-4 inviable one allele is deleted and the other is placed under repressible Tet promoter C. albicans orf19.4788 ORF ARG5,6 CAL0004595 PMID: 10074081|CGD_REF: CAL0080678 homozygous diploid, classical genetics null Not recorded auxotrophy arginine C. albicans orf19.4788 ORF ARG5,6 CAL0004595 PMID: 9043106|CGD_REF: CAL0080776 homozygous diploid, classical genetics null Not recorded auxotrophy arginine C. albicans orf19.4791 ORF CAL0004609 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient YPD medium C. albicans orf19.4791 ORF CAL0004609 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient SC medium C. albicans orf19.4791 ORF CAL0004609 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient YNB medium C. albicans orf19.4791 ORF CAL0004609 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient SLAD medium C. albicans orf19.4792 ORF CAL0004610 PMID: 21414038|CGD_REF: CAL0141808 homozygous diploid, classical genetics null BWP17 viable C. albicans orf19.4792 ORF CAL0004610 PMID: 21414038|CGD_REF: CAL0141808 homozygous diploid, classical genetics null BWP17 biofilm formation: normal C. albicans orf19.4798 ORF CAL0004618 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.4799 ORF CEF1 CAL0004619 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.4799 ORF CEF1 CAL0004619 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient YPD medium C. albicans orf19.48 ORF RPM2 CAL0000580 PMID: 12524333|CGD_REF: CAL0080691 homozygous diploid, systematic mutation set (homozygous insertion mutants generated with URA3-ARG4-URA3 (UAU1) cassette) null BWP17 inviable homozygous null mutant strain could not be recovered, suggesting that the gene is essential under the selection conditions C. albicans orf19.480 ORF CAL0005823 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 invasive growth: decreased solid SLAD media C. albicans orf19.4800 ORF RIM20 CAL0005286 PMID: 15590834|CGD_REF: CAL0082485 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased lithium(1+) C. albicans orf19.4800 ORF RIM20 CAL0005286 PMID: 12819929|CGD_REF: CAL0081778 homozygous diploid, classical genetics null Not recorded vegetative growth: decreased rate alkaline pH C. albicans orf19.4800 ORF RIM20 CAL0005286 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.4800 ORF RIM20 CAL0005286 PMID: 10074081|CGD_REF: CAL0080678 heterozygous diploid, classical genetics null Not recorded viable C. albicans orf19.4800 ORF RIM20 CAL0005286 PMID: 10074081|CGD_REF: CAL0080678 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.4800 ORF RIM20 CAL0005286 PMID: 15590834|CGD_REF: CAL0082485 homozygous diploid, classical genetics null Not recorded alkaline pH resistance: decreased pH 9 C. albicans orf19.4800 ORF RIM20 CAL0005286 PMID: 10629054|CGD_REF: CAL0081720 homozygous diploid, classical genetics null rim20::URA3/rim20::ARG4 BWP17 hyphal growth: absent alkaline pH C. albicans orf19.4800 ORF RIM20 CAL0005286 PMID: 10629054|CGD_REF: CAL0081720 homozygous diploid, classical genetics null rim20::URA3/rim20::ARG4 BWP17 viable C. albicans orf19.4800 ORF RIM20 CAL0005286 PMID: 10074081|CGD_REF: CAL0080678 homozygous diploid, classical genetics null Not recorded filamentous growth: absent solid Spider medium C. albicans orf19.4800 ORF RIM20 CAL0005286 PMID: 15590834|CGD_REF: CAL0082485 homozygous diploid, classical genetics null BWP17 filamentous growth: absent solid M199 medium, pH 8 C. albicans orf19.4800 ORF RIM20 CAL0005286 PMID: 22427429|CGD_REF: CAL0000156990 homozygous diploid, classical genetics null BWP17 protein/peptide modification: absent mutants don't process RIM8-HA RIM8-HA C. albicans orf19.4800 ORF RIM20 CAL0005286 PMID: 20375342|CGD_REF: CAL0125177 homozygous diploid, classical genetics null BWP17 filamentous growth: decreased solid M199 medium pH 7.3 or 8.0 C. albicans orf19.4800 ORF RIM20 CAL0005286 PMID: 20375342|CGD_REF: CAL0125177 homozygous diploid, classical genetics null BWP17 virulence: decreased BALB/C mice mouse corneal infection C. albicans orf19.4800 ORF RIM20 CAL0005286 PMID: 20375342|CGD_REF: CAL0125177 homozygous diploid, classical genetics null BWP17 invasive growth: decreased porcine corneal tissue depth of hyphal penetration into corneal tissue is reduced ex vivo model of infection C. albicans orf19.4801 ORF CAL0005287 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.4802 ORF FTH1 CAL0005288 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.4802 ORF FTH1 CAL0005288 PMID: 14663094|CGD_REF: CAL0080633 homozygous diploid, systematic mutation set (homozygous insertion mutants generated with URA3-ARG4-URA3 (UAU1) cassette) null BWP17 viable C. albicans orf19.4802 ORF FTH1 CAL0005288 PMID: 14507372|CGD_REF: CAL0088818 heterozygous diploid, large-scale survey (large-scale identification of essential genes by gene replacement and conditional expression (GRACE) method) repressible CAI-4 inviable one allele is deleted and the other is placed under repressible Tet promoter C. albicans orf19.4802 ORF FTH1 CAL0005288 PMID: 23856128|CGD_REF: CAL0000172540 homozygous diploid, classical genetics null BWP17 resistance to chemicals: decreased propolis C. albicans orf19.4804 ORF LIP2 CAL0005290 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.4804 ORF LIP2 CAL0005290 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.4804 ORF LIP2 CAL0005290 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.4804 ORF LIP2 CAL0005290 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.4804 ORF LIP2 CAL0005290 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.4805 ORF CAL0005291 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.4805 ORF CAL0005291 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.4805 ORF CAL0005291 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.4805 ORF CAL0005291 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.4807 ORF CAL0005294 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.4808 ORF NUP188 CAL0005296 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.4808 ORF NUP188 CAL0005296 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient YPD medium C. albicans orf19.4808 ORF NUP188 CAL0005296 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient SC medium C. albicans orf19.4808 ORF NUP188 CAL0005296 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient SLAD medium C. albicans orf19.4809 ORF ERG12 CAL0005299 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.4809 ORF ERG12 CAL0005299 PMID: 21135205|CGD_REF: CAL0139967 heterozygous diploid, large-scale survey (large-scale identification of genes essential for virulence in mouse) repressible CAI-4 virulence: absent mouse intravenous infection C. albicans orf19.481 ORF GCD1 CAL0005825 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.4811 ORF CAL0005311 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.4813 ORF GUA1 CAL0005313 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.4813 ORF GUA1 CAL0005313 PMID: 20082641|CGD_REF: CAL0124782 homozygous diploid, classical genetics null viable C. albicans orf19.4813 ORF GUA1 CAL0005313 PMID: 20082641|CGD_REF: CAL0124782 homozygous diploid, classical genetics null auxotrophy C. albicans orf19.4813 ORF GUA1 CAL0005313 PMID: 20082641|CGD_REF: CAL0124782 homozygous diploid, classical genetics null resistance to chemicals 6-azauracil C. albicans orf19.4813 ORF GUA1 CAL0005313 PMID: 20082641|CGD_REF: CAL0124782 homozygous diploid, classical genetics null virulence: decreased completely avirulent mouse intravenous infection C. albicans orf19.4813 ORF GUA1 CAL0005313 PMID: 21135205|CGD_REF: CAL0139967 heterozygous diploid, large-scale survey (large-scale identification of genes essential for virulence in mouse) repressible CAI-4 virulence: absent mouse intravenous infection C. albicans orf19.4815 ORF YTM1 CAL0005315 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.4815 ORF YTM1 CAL0005315 PMID: 12773383|CGD_REF: CAL0087974 heterozygous diploid, classical genetics (haploinsufficient phenotype assay) null CAI-4 filamentous growth: increased solid Spider medium heterozygous transposon insertion C. albicans orf19.4815 ORF YTM1 CAL0005315 PMID: 12773383|CGD_REF: CAL0087974 heterozygous diploid, classical genetics (haploinsufficient phenotype assay) null CAI-4 colony size: decreased solid Spider medium heterozygous transposon insertion C. albicans orf19.4815 ORF YTM1 CAL0005315 PMID: 21135205|CGD_REF: CAL0139967 heterozygous diploid, large-scale survey (large-scale identification of genes essential for virulence in mouse) repressible CAI-4 virulence: absent mouse intravenous infection C. albicans orf19.4817 ORF RAM2 CAL0005317 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.4817 ORF RAM2 CAL0005317 PMID: 16607011|CGD_REF: CAL0115846 heterozygous diploid, classical genetics null SC5314 viable C. albicans orf19.4817 ORF RAM2 CAL0005317 PMID: 12576598|CGD_REF: CAL0081764 homozygous diploid, classical genetics null Not recorded inviable homozygous null mutant strain could not be recovered, suggesting that the gene is essential under the selection conditions C. albicans orf19.4817 ORF RAM2 CAL0005317 PMID: 16607011|CGD_REF: CAL0115846 homozygous diploid, classical genetics null Not recorded inviable homozygous null mutant strain could not be recovered, suggesting that the gene is essential under the selection conditions C. albicans orf19.4817 ORF RAM2 CAL0005317 PMID: 16607011|CGD_REF: CAL0115846 heterozygous diploid, classical genetics repressible SC5314 inviable C. albicans orf19.4819 ORF CAL0005322 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient YNB medium C. albicans orf19.4819 ORF CAL0005322 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient SLAD medium C. albicans orf19.482 ORF RPT4 CAL0005827 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.4820 ORF CAL0005330 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.4821 ORF LIP1 CAL0005331 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.4821 ORF LIP1 CAL0005331 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.4821 ORF LIP1 CAL0005331 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.4821 ORF LIP1 CAL0005331 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.4821 ORF LIP1 CAL0005331 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.4822 ORF LIP10 CAL0005332 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.4822 ORF LIP10 CAL0005332 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.4822 ORF LIP10 CAL0005332 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.4822 ORF LIP10 CAL0005332 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.4822 ORF LIP10 CAL0005332 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.4823 ORF LIP6 CAL0005333 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.4823 ORF LIP6 CAL0005333 PMID: 14663094|CGD_REF: CAL0080633 homozygous diploid, systematic mutation set (homozygous insertion mutants generated with URA3-ARG4-URA3 (UAU1) cassette) null BWP17 viable C. albicans orf19.4823 ORF LIP6 CAL0005333 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.4823 ORF LIP6 CAL0005333 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.4823 ORF LIP6 CAL0005333 PMID: 23856128|CGD_REF: CAL0000172540 homozygous diploid, classical genetics null BWP17 resistance to chemicals: decreased propolis C. albicans orf19.4823 ORF LIP6 CAL0005333 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.4823 ORF LIP6 CAL0005333 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.4826 ORF IDH1 CAL0005337 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.4826 ORF IDH1 CAL0005337 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 invasive growth: decreased solid SLAD media C. albicans orf19.4827 ORF ADE12 CAL0005339 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.4829 ORF DOA1 CAL0005343 PMID: 17379712|CGD_REF: CAL0117537 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased isoflurane C. albicans orf19.4829 ORF DOA1 CAL0005343 PMID: 17379712|CGD_REF: CAL0117537 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased itraconazole C. albicans orf19.4829 ORF DOA1 CAL0005343 PMID: 17379712|CGD_REF: CAL0117537 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased propranolol C. albicans orf19.4829 ORF DOA1 CAL0005343 PMID: 17379712|CGD_REF: CAL0117537 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased sodium dodecyl sulfate C. albicans orf19.4829 ORF DOA1 CAL0005343 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.4829 ORF DOA1 CAL0005343 PMID: 17379712|CGD_REF: CAL0117537 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.4829 ORF DOA1 CAL0005343 PMID: 17379712|CGD_REF: CAL0117537 homozygous diploid, classical genetics null Not recorded protein activity: decreased phospholipase C. albicans orf19.4829 ORF DOA1 CAL0005343 PMID: 17379712|CGD_REF: CAL0117537 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased caffeine C. albicans orf19.4829 ORF DOA1 CAL0005343 PMID: 17379712|CGD_REF: CAL0117537 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased butan-1-ol C. albicans orf19.4829 ORF DOA1 CAL0005343 PMID: 17379712|CGD_REF: CAL0117537 homozygous diploid, classical genetics null CAI-4 filamentous growth: abnormal liquid SD medium mixture of pseudohyphae and true hyphae C. albicans orf19.4829 ORF DOA1 CAL0005343 PMID: 17379712|CGD_REF: CAL0117537 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased nocodazole C. albicans orf19.4829 ORF DOA1 CAL0005343 PMID: 17379712|CGD_REF: CAL0117537 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased ethylenediaminetetraacetic acid C. albicans orf19.4831 ORF MTS1 CAL0005352 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.4831 ORF MTS1 CAL0005352 PMID: 20019081|CGD_REF: CAL0124887 homozygous diploid, classical genetics null Other C. albicans viable C. albicans orf19.4831 ORF MTS1 CAL0005352 PMID: 20019081|CGD_REF: CAL0124887 homozygous diploid, classical genetics null Other C. albicans resistance to chemicals: decreased Micafungin C. albicans orf19.4831 ORF MTS1 CAL0005352 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: decreased growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.4831 ORF MTS1 CAL0005352 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.4831 ORF MTS1 CAL0005352 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.4831 ORF MTS1 CAL0005352 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, classical genetics null SN152 virulence: decreased BALB/C mice slight decrease mouse intravenous infection C. albicans orf19.4831 ORF MTS1 CAL0005352 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, classical genetics null SN152 chemical compound accumulation: absent glucosylceramide mature glucosylceramide is absent from cellular membranes C. albicans orf19.4831 ORF MTS1 CAL0005352 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.4833 ORF MLS1 CAL0005353 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.4835 ORF CAL0005357 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.4836 ORF URA1 CAL0005359 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.4837 ORF DAM1 CAL0005362 PMID: 21571923|CGD_REF: CAL0142042 homozygous diploid, classical genetics repressible dam1::HIS1/MET3(p)-DAM1 Other C. albicans cell cycle progression: arrested repressing condition mutant accumulates large budded cells after 4h of growth under nonpermissive conditions, prolonged incubation leads to a transition to an elongated (pseudohyphal-like) bud C. albicans orf19.4837 ORF DAM1 CAL0005362 PMID: 21571923|CGD_REF: CAL0142042 homozygous diploid, classical genetics repressible dam1::HIS1/MET3(p)-DAM1 Other C. albicans inviable repressing condition C. albicans orf19.4837 ORF DAM1 CAL0005362 PMID: 21571923|CGD_REF: CAL0142042 homozygous diploid, classical genetics repressible dam1::HIS1/MET3(p)-DAM1 Other C. albicans chromosome segregation: abnormal repressing condition C. albicans orf19.4837 ORF DAM1 CAL0005362 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient SC medium C. albicans orf19.4837 ORF DAM1 CAL0005362 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 invasive growth: decreased solid SLAD media C. albicans orf19.4841 ORF SHY1 CAL0005374 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.4843 ORF CAL0005376 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.4843 ORF CAL0005376 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.4843 ORF CAL0005376 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.4843 ORF CAL0005376 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.4844 ORF CAL0005378 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: decreased growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.4844 ORF CAL0005378 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: abnormal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.4844 ORF CAL0005378 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: decreased rate liquid synthetic complete medium C. albicans orf19.4844 ORF CAL0005378 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.4845 ORF TVP18 CAL0005379 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.4845 ORF TVP18 CAL0005379 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.4845 ORF TVP18 CAL0005379 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.4845 ORF TVP18 CAL0005379 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.4845 ORF TVP18 CAL0005379 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.4846 ORF CAL0005381 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.4846 ORF CAL0005381 PMID: 14663094|CGD_REF: CAL0080633 homozygous diploid, systematic mutation set (homozygous insertion mutants generated with URA3-ARG4-URA3 (UAU1) cassette) null BWP17 viable C. albicans orf19.4847 ORF CAF0007022 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient YNB medium C. albicans orf19.4847 ORF CAF0007022 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient SLAD medium C. albicans orf19.4848 ORF SKI3 CAL0005384 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.4849 ORF CAL0005386 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.485 ORF CAL0005835 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.485 ORF CAL0005835 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient YPD medium C. albicans orf19.485 ORF CAL0005835 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient SC medium C. albicans orf19.4850 ORF CAL0005398 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.4851 ORF TFA1 CAL0005399 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.4853 ORF HCM1 CAL0005400 PMID: 20041210|CGD_REF: CAL0124764 homozygous diploid, systematic mutation set null SN152 resistance to chemicals: decreased fluconazole strongly sensitive C. albicans orf19.4853 ORF HCM1 CAL0005400 PMID: 20041210|CGD_REF: CAL0124764 homozygous diploid, systematic mutation set null SN152 vegetative growth: decreased SD or YEPD media at 30 deg C strongly decreased C. albicans orf19.4853 ORF HCM1 CAL0005400 PMID: 12455696|CGD_REF: CAL0080790 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.4853 ORF HCM1 CAL0005400 PMID: 12455696|CGD_REF: CAL0080790 homozygous diploid, classical genetics null Not recorded cellular morphology: normal C. albicans orf19.4853 ORF HCM1 CAL0005400 PMID: 12455696|CGD_REF: CAL0080790 homozygous diploid, classical genetics null Not recorded colony appearance: normal C. albicans orf19.4853 ORF HCM1 CAL0005400 PMID: 20041210|CGD_REF: CAL0124764 homozygous diploid, systematic mutation set null SN152 colony color: abnormal CHROMagar medium at 37 deg C darker than normal C. albicans orf19.4855 ORF BUD31 CAL0005402 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.4856 ORF LIP3 CAL0005403 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.4856 ORF LIP3 CAL0005403 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.4856 ORF LIP3 CAL0005403 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.4856 ORF LIP3 CAL0005403 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.4856 ORF LIP3 CAL0005403 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.4858 ORF VPS41 CAL0005408 PMID: 19040629|CGD_REF: CAL0121263 heterozygous diploid, classical genetics repressible Not recorded vacuolar morphology: abnormal fragmented vacuoles in yeast-like cells C. albicans orf19.4858 ORF VPS41 CAL0005408 PMID: 19040629|CGD_REF: CAL0121263 heterozygous diploid, classical genetics repressible Not recorded vacuolar morphology: abnormal increased vacuole content in hyphae C. albicans orf19.4858 ORF VPS41 CAL0005408 PMID: 12773383|CGD_REF: CAL0087974 heterozygous diploid, classical genetics (haploinsufficient phenotype assay) null CAI-4 viable heterozygous transposon insertion C. albicans orf19.4858 ORF VPS41 CAL0005408 PMID: 19040629|CGD_REF: CAL0121263 heterozygous diploid, classical genetics repressible CAI-4 hyphal growth: abnormal altered branching frequency in hyphae C. albicans orf19.4858 ORF VPS41 CAL0005408 PMID: 12773383|CGD_REF: CAL0087974 heterozygous diploid, classical genetics (haploinsufficient phenotype assay) null CAI-4 filamentous growth: decreased solid Spider medium heterozygous transposon insertion C. albicans orf19.4858 ORF VPS41 CAL0005408 PMID: 18466294|CGD_REF: CAL0119004 homozygous diploid, classical genetics null Not recorded utilization of iron source: absent hemoglobin C. albicans orf19.486 ORF NIP100 CAL0005838 PMID: 18211963|CGD_REF: CAL0118861 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.486 ORF NIP100 CAL0005838 PMID: 18211963|CGD_REF: CAL0118861 homozygous diploid, classical genetics null Not recorded pseudohyphal growth: abnormal conditions inducing yeast-form growth pseudohyphal growth occurs along with yeast-form growth C. albicans orf19.486 ORF NIP100 CAL0005838 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient SLAD medium C. albicans orf19.4862 ORF CAL0005431 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.4863 ORF PDC2 CAL0005432 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.4864 ORF CAL0005433 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.4866 ORF CPP1 CAL0005436 PMID: 9398674|CGD_REF: CAL0080970 homozygous diploid, classical genetics null CAI-4 germ tube formation: normal liquid media C. albicans orf19.4866 ORF CPP1 CAL0005436 PMID: 9398674|CGD_REF: CAL0080970 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.4866 ORF CPP1 CAL0005436 PMID: 9596738|CGD_REF: CAL0080971 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.4866 ORF CPP1 CAL0005436 PMID: 9398674|CGD_REF: CAL0080970 homozygous diploid, classical genetics null CAI-4 hyphal growth: abnormal solid serum-containing medium at 37 deg C altered hyphal budding C. albicans orf19.4866 ORF CPP1 CAL0005436 PMID: 9398674|CGD_REF: CAL0080970 homozygous diploid, classical genetics null CAI-4 hyphal growth: increased various solid media at 23 deg C hyphal growth under non hyphal-inducing conditions C. albicans orf19.4866 ORF CPP1 CAL0005436 PMID: 9398674|CGD_REF: CAL0080970 homozygous diploid, classical genetics null CAI-4 hyphal growth: decreased rate solid serum-containing medium at 37 deg C C. albicans orf19.4866 ORF CPP1 CAL0005436 PMID: 9398674|CGD_REF: CAL0080970 homozygous diploid, classical genetics null CAI-4 hyphal growth: normal solid Spider medium plus glucose or mannitol at 37 deg C C. albicans orf19.4866 ORF CPP1 CAL0005436 PMID: 9596738|CGD_REF: CAL0080971 homozygous diploid, classical genetics null CAI-4 hyphal growth: decreased rate solid serum-containing medium C. albicans orf19.4866 ORF CPP1 CAL0005436 PMID: 9596738|CGD_REF: CAL0080971 homozygous diploid, classical genetics null CAI-4 hyphal growth: increased solid SLAD medium C. albicans orf19.4866 ORF CPP1 CAL0005436 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: decreased growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.4866 ORF CPP1 CAL0005436 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: abnormal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.4866 ORF CPP1 CAL0005436 PMID: 12381467|CGD_REF: CAL0087147 homozygous diploid, classical genetics null Not recorded virulence: decreased Galleria mellonella (Greater Wax Moth) larvae insect infection C. albicans orf19.4866 ORF CPP1 CAL0005436 PMID: 9398674|CGD_REF: CAL0080970 homozygous diploid, classical genetics null Not recorded virulence: decreased exhibits decreased kidney colonization mouse intravenous infection C. albicans orf19.4866 ORF CPP1 CAL0005436 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.4866 ORF CPP1 CAL0005436 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient YNB medium C. albicans orf19.4866 ORF CPP1 CAL0005436 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient SLAD medium C. albicans orf19.4866 ORF CPP1 CAL0005436 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.4867 ORF SWE1 CAL0005438 PMID: 14769857|CGD_REF: CAL0080845 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.4867 ORF SWE1 CAL0005438 PMID: 15659158|CGD_REF: CAL0082298 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.4867 ORF SWE1 CAL0005438 PMID: 19778960|CGD_REF: CAL0124332 homozygous diploid, classical genetics null BWP17 virulence: decreased mouse intravenous infection C. albicans orf19.4867 ORF SWE1 CAL0005438 PMID: 14769857|CGD_REF: CAL0080845 homozygous diploid, classical genetics null BWP17 hyphal growth: normal C. albicans orf19.4867 ORF SWE1 CAL0005438 PMID: 14769857|CGD_REF: CAL0080845 homozygous diploid, classical genetics null Not recorded cell size: decreased cells are small, rounded, and sometimes binucleate C. albicans orf19.4867 ORF SWE1 CAL0005438 PMID: 14769857|CGD_REF: CAL0080845 homozygous diploid, classical genetics null BWP17 pseudohyphal growth: normal C. albicans orf19.4869 ORF SFU1 CAL0005442 PMID: 15387822|CGD_REF: CAL0082083 heterozygous diploid, classical genetics null Not recorded viable C. albicans orf19.4869 ORF SFU1 CAL0005442 PMID: 15387822|CGD_REF: CAL0082083 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.4869 ORF SFU1 CAL0005442 PMID: 15387822|CGD_REF: CAL0082083 heterozygous diploid, classical genetics null RM1000 hyphal growth: normal liquid Lee's or YPD plus serum media C. albicans orf19.4869 ORF SFU1 CAL0005442 PMID: 15387822|CGD_REF: CAL0082083 homozygous diploid, classical genetics null RM1000 hyphal growth: normal liquid Lee's or YPD plus serum media C. albicans orf19.4869 ORF SFU1 CAL0005442 PMID: 20041210|CGD_REF: CAL0124764 homozygous diploid, systematic mutation set null SN152 metal resistance: decreased copper(2+) severely sensitive C. albicans orf19.4869 ORF SFU1 CAL0005442 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.4869 ORF SFU1 CAL0005442 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.4869 ORF SFU1 CAL0005442 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.4869 ORF SFU1 CAL0005442 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.487 ORF SPT14 CAL0005841 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.487 ORF SPT14 CAL0005841 PMID: 15964282|CGD_REF: CAL0114274 homozygous diploid, systematic mutation set (split-marker transposon insertion strategy to disrupt both alleles) null BWP17 inviable homozygous null mutant strain could not be recovered, suggesting that the gene is essential under the selection conditions C. albicans orf19.4870 ORF DBP3 CAL0005460 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.4871 ORF ERO1 CAL0005461 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.4872 ORF CAL0005462 PMID: 14663094|CGD_REF: CAL0080633 homozygous diploid, systematic mutation set (homozygous insertion mutants generated with URA3-ARG4-URA3 (UAU1) cassette) null BWP17 viable C. albicans orf19.4874 ORF MNN23 CAL0005465 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.4874 ORF MNN23 CAL0005465 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, competitive growth (haploinsufficient phenotype assay, barcode deletion set) null SC5314 resistance to chemicals: decreased amphotericin B C. albicans orf19.4874 ORF MNN23 CAL0005465 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, competitive growth (haploinsufficient phenotype assay, barcode deletion set) null SC5314 resistance to chemicals: decreased ergosterol analogs (ECC69 and/or ECC1384) C. albicans orf19.4874 ORF MNN23 CAL0005465 PMID: 23633946|CGD_REF: CAL0000172007 homozygous diploid, classical genetics null mnn23::dpl200/mnn23::dpl200 CAI-4 chemical compound accumulation: decreased mannan slight decrease in extracted cell wall mannan content (correlates with increased beta-glucan exposure on cells) C. albicans orf19.4874 ORF MNN23 CAL0005465 PMID: 23633946|CGD_REF: CAL0000172007 homozygous diploid, classical genetics null mnn23::dpl200/mnn23::dpl200 CAI-4 thermotolerance: decreased YPD agar plates, 42 degrees C C. albicans orf19.4874 ORF MNN23 CAL0005465 PMID: 23633946|CGD_REF: CAL0000172007 homozygous diploid, classical genetics null mnn23::dpl200/mnn23::dpl200 CAI-4 resistance to chemicals: decreased Calcofluor White YPD agar plates containing 100 ug/ml CFW C. albicans orf19.488 ORF MEX67 CAL0005845 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.488 ORF MEX67 CAL0005845 PMID: 21135205|CGD_REF: CAL0139967 heterozygous diploid, large-scale survey (large-scale identification of genes essential for virulence in mouse) repressible CAI-4 virulence: absent mouse intravenous infection C. albicans orf19.4882 ORF CAL0005496 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.4882 ORF CAL0005496 PMID: 21135205|CGD_REF: CAL0139967 heterozygous diploid, competitive growth (large-scale identification of genes essential for virulence in mouse) repressible CAI-4 virulence: decreased mouse intravenous infection C. albicans orf19.4883 ORF CAL0005497 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.4883 ORF CAL0005497 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 invasive growth: decreased solid SLAD media C. albicans orf19.4884 ORF WOR1 CAL0005498 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.4884 ORF WOR1 CAL0005498 PMID: 16950924|CGD_REF: CAL0116772 heterozygous diploid, classical genetics null Not recorded viable C. albicans orf19.4884 ORF WOR1 CAL0005498 PMID: 16950924|CGD_REF: CAL0116772 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.4884 ORF WOR1 CAL0005498 PMID: 17873081|CGD_REF: CAL0118685 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.4884 ORF WOR1 CAL0005498 PMID: 19555456|CGD_REF: CAL0123821 homozygous diploid, classical genetics null Not recorded mating response: absent human beta-defensin 2 homozygous wor1/wor1 null, MTLa/MTLa strain C. albicans orf19.4884 ORF WOR1 CAL0005498 PMID: 16905649|CGD_REF: CAL0116523 heterozygous diploid, classical genetics overexpression Not recorded phenotypic switching: increased all white cells convert to opaque upon ectopic expresssion C. albicans orf19.4884 ORF WOR1 CAL0005498 PMID: 16950924|CGD_REF: CAL0116772 heterozygous diploid, classical genetics misexpression Not recorded phenotypic switching: abnormal induction in opaque cells inhibits heat-induced opaque-to-white switching C. albicans orf19.4884 ORF WOR1 CAL0005498 PMID: 16950924|CGD_REF: CAL0116772 heterozygous diploid, classical genetics misexpression Not recorded phenotypic switching: abnormal induction in white MTLa homozygotes causes white-to-opaque switching C. albicans orf19.4884 ORF WOR1 CAL0005498 PMID: 16899543|CGD_REF: CAL0116553 homozygous diploid, classical genetics null Not recorded phenotypic switching: absent white-to-opaque switching C. albicans orf19.4884 ORF WOR1 CAL0005498 PMID: 16899543|CGD_REF: CAL0116553 heterozygous diploid, classical genetics overexpression Not recorded phenotypic switching: increased white-to-opaque switching C. albicans orf19.4884 ORF WOR1 CAL0005498 PMID: 16905649|CGD_REF: CAL0116523 homozygous diploid, classical genetics null Not recorded phenotypic switching: absent white-to-opaque switching C. albicans orf19.4884 ORF WOR1 CAL0005498 PMID: 16950924|CGD_REF: CAL0116772 homozygous diploid, classical genetics null Not recorded phenotypic switching: absent white-to-opaque switching C. albicans orf19.4884 ORF WOR1 CAL0005498 PMID: 16950924|CGD_REF: CAL0116772 heterozygous diploid, classical genetics null Not recorded phenotypic switching: decreased white-to-opaque switching C. albicans orf19.4884 ORF WOR1 CAL0005498 PMID: 19200725|CGD_REF: CAL0122386 homozygous diploid, classical genetics null Not recorded phenotypic switching: decreased white-to-opaque switching; defect is not rescued by high (20%) CO2 C. albicans orf19.4884 ORF WOR1 CAL0005498 PMID: 21498642|CGD_REF: CAL0141911 homozygous diploid, classical genetics null P37005 biofilm formation: decreased decreased biofilm mass C. albicans orf19.4884 ORF WOR1 CAL0005498 PMID: 21498642|CGD_REF: CAL0141911 homozygous diploid, classical genetics null P37005 RNA accumulation: decreased decreased biofilm mass EAP1 mRNA C. albicans orf19.4884 ORF WOR1 CAL0005498 PMID: 21498642|CGD_REF: CAL0141911 homozygous diploid, classical genetics null P37005 RNA accumulation: decreased EAP1 mRNA C. albicans orf19.4884 ORF WOR1 CAL0005498 PMID: 21498642|CGD_REF: CAL0141911 homozygous diploid, classical genetics null P37005 RNA accumulation: decreased CSH1 mRNA C. albicans orf19.4884 ORF WOR1 CAL0005498 PMID: 21498642|CGD_REF: CAL0141911 homozygous diploid, classical genetics null P37005 RNA accumulation: decreased RBT5 mRNA C. albicans orf19.4884 ORF WOR1 CAL0005498 PMID: 21498642|CGD_REF: CAL0141911 homozygous diploid, classical genetics null P37005 RNA accumulation: decreased SUN41 mRNA C. albicans orf19.4884 ORF WOR1 CAL0005498 PMID: 21498642|CGD_REF: CAL0141911 homozygous diploid, classical genetics null P37005 RNA accumulation: decreased CEK1 mRNA C. albicans orf19.4884 ORF WOR1 CAL0005498 PMID: 21498642|CGD_REF: CAL0141911 homozygous diploid, classical genetics null P37005 RNA accumulation: decreased RBT1 mRNA C. albicans orf19.4885 ORF MIR1 CAL0005500 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.4886 ORF CAL0005502 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 invasive growth: decreased solid SLAD media C. albicans orf19.4887 ORF ECM21 CAL0005504 PMID: 14663094|CGD_REF: CAL0080633 homozygous diploid, systematic mutation set (homozygous insertion mutants generated with URA3-ARG4-URA3 (UAU1) cassette) null BWP17 viable C. albicans orf19.4887 ORF ECM21 CAL0005504 PMID: 17873081|CGD_REF: CAL0118685 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.4889 ORF CAL0005508 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.489 ORF DAP1 CAL0005848 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.4890 ORF CLA4 CAL0005519 PMID: 16467475|CGD_REF: CAL0115509 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased Calcofluor White C. albicans orf19.4890 ORF CLA4 CAL0005519 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.4890 ORF CLA4 CAL0005519 PMID: 9259554|CGD_REF: CAL0080869 homozygous diploid, classical genetics null Not recorded viable wild-type growth rate C. albicans orf19.4890 ORF CLA4 CAL0005519 PMID: 9259554|CGD_REF: CAL0080869 heterozygous diploid, classical genetics null Not recorded viable C. albicans orf19.4890 ORF CLA4 CAL0005519 PMID: 16467475|CGD_REF: CAL0115509 homozygous diploid, classical genetics null Not recorded protein/peptide accumulation: decreased phenotype is suppressed by hog1 mutation Cek1p C. albicans orf19.4890 ORF CLA4 CAL0005519 PMID: 9259554|CGD_REF: CAL0080869 homozygous diploid, classical genetics null CAI-4 hyphal growth: decreased various liquid and solid media decreased hyphal growth ( tested) C. albicans orf19.4890 ORF CLA4 CAL0005519 PMID: 10816502|CGD_REF: CAL0081036 homozygous diploid, classical genetics null cla4::hisG/cla4::hisG-URA3-hisG CAI-4 hyphal growth: abnormal clumped and shorter hyphae upon exposure to endothelial cells from human umbilical cord veins C. albicans orf19.4890 ORF CLA4 CAL0005519 PMID: 9259554|CGD_REF: CAL0080869 heterozygous diploid, classical genetics null Not recorded cellular morphology: normal C. albicans orf19.4890 ORF CLA4 CAL0005519 PMID: 16002645|CGD_REF: CAL0114398 homozygous diploid, classical genetics null CAI-4 chlamydospore formation: abnormal bulged suspensor cells and truncated or highly branched filaments C. albicans orf19.4890 ORF CLA4 CAL0005519 PMID: 16002645|CGD_REF: CAL0114398 homozygous diploid, classical genetics null Not recorded chlamydospore formation: decreased C. albicans orf19.4890 ORF CLA4 CAL0005519 PMID: 9259554|CGD_REF: CAL0080869 homozygous diploid, classical genetics null Not recorded cytokinesis: decreased cells are multibudded and multinucleate C. albicans orf19.4890 ORF CLA4 CAL0005519 PMID: 16467475|CGD_REF: CAL0115509 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased Congo Red C. albicans orf19.4890 ORF CLA4 CAL0005519 PMID: 16467475|CGD_REF: CAL0115509 homozygous diploid, classical genetics null RM1000 filamentous growth: normal 100% serum C. albicans orf19.4890 ORF CLA4 CAL0005519 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: decreased growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.4890 ORF CLA4 CAL0005519 PMID: 12379711|CGD_REF: CAL0081037 homozygous diploid, classical genetics null CAI-4 resistance to killing by host cells: increased in vitro model of infection (RAW264.7 macrophages) C. albicans orf19.4890 ORF CLA4 CAL0005519 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: abnormal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.4890 ORF CLA4 CAL0005519 PMID: 12381467|CGD_REF: CAL0087147 homozygous diploid, classical genetics null Not recorded virulence: decreased insect infection C. albicans orf19.4890 ORF CLA4 CAL0005519 PMID: 9259554|CGD_REF: CAL0080869 homozygous diploid, classical genetics null Not recorded virulence: decreased exhibits decreased kidney colonization mouse intravenous infection C. albicans orf19.4890 ORF CLA4 CAL0005519 PMID: 9259554|CGD_REF: CAL0080869 homozygous diploid, classical genetics null Not recorded virulence: absent mouse intravenous infection C. albicans orf19.4890 ORF CLA4 CAL0005519 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: decreased rate liquid synthetic complete medium C. albicans orf19.4890 ORF CLA4 CAL0005519 PMID: 20140194|CGD_REF: CAL0124995 homozygous diploid, classical genetics null Other C. albicans resistance to chemicals: decreased caspofungin C. albicans orf19.4890 ORF CLA4 CAL0005519 PMID: 20140194|CGD_REF: CAL0124995 homozygous diploid, classical genetics null Other C. albicans viable caspofungin C. albicans orf19.4890 ORF CLA4 CAL0005519 PMID: 20140194|CGD_REF: CAL0124995 homozygous diploid, classical genetics null Other C. albicans viable C. albicans orf19.4890 ORF CLA4 CAL0005519 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.4892 ORF TPK1 CAL0005520 PMID: 16823887|CGD_REF: CAL0116267 homozygous diploid, classical genetics null Not recorded germ tube formation: delayed C. albicans orf19.4892 ORF TPK1 CAL0005520 PMID: 19391100|CGD_REF: CAL0122781 homozygous diploid, classical genetics null Not recorded thermotolerance: decreased C. albicans orf19.4892 ORF TPK1 CAL0005520 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.4892 ORF TPK1 CAL0005520 PMID: 11886556|CGD_REF: CAL0081621 homozygous diploid, classical genetics null Not recorded viable no apparent phenotype C. albicans orf19.4892 ORF TPK1 CAL0005520 PMID: 12798685|CGD_REF: CAL0081196 heterozygous diploid, classical genetics overexpression CAI-4 viable C. albicans orf19.4892 ORF TPK1 CAL0005520 PMID: 16407097|CGD_REF: CAL0115390 homozygous diploid, classical genetics null Not recorded apoptosis: normal C. albicans orf19.4892 ORF TPK1 CAL0005520 PMID: 15760450|CGD_REF: CAL0104038 heterozygous diploid, classical genetics null CAI-4 hyphal growth: normal FaDu or OKF6/TERT-2 epithelial cells reintegrant in vitro model of infection C. albicans orf19.4892 ORF TPK1 CAL0005520 PMID: 15760450|CGD_REF: CAL0104038 homozygous diploid, classical genetics null CAI-4 hyphal growth: normal FaDu or OKF6/TERT-2 epithelial cells in vitro model of infection C. albicans orf19.4892 ORF TPK1 CAL0005520 PMID: 11886556|CGD_REF: CAL0081621 heterozygous diploid, classical genetics overexpression Not recorded hyphal growth: abnormal SCAA medium hyphal growth occurs in non-inducing conditions C. albicans orf19.4892 ORF TPK1 CAL0005520 PMID: 11886556|CGD_REF: CAL0081621 homozygous diploid, classical genetics null Not recorded hyphal growth: absent liquid serum-containing or Spider media C. albicans orf19.4892 ORF TPK1 CAL0005520 PMID: 22882910|CGD_REF: CAL0000157683 homozygous diploid, classical genetics null BWP17 biofilm formation: increased C. albicans orf19.4892 ORF TPK1 CAL0005520 PMID: 22882910|CGD_REF: CAL0000157683 homozygous diploid, classical genetics null BWP17 cell wall morphology: abnormal C. albicans orf19.4892 ORF TPK1 CAL0005520 PMID: 22882910|CGD_REF: CAL0000157683 homozygous diploid, classical genetics null BWP17 resistance to chemicals: decreased caspofungin C. albicans orf19.4892 ORF TPK1 CAL0005520 PMID: 19391100|CGD_REF: CAL0122781 homozygous diploid, classical genetics null Not recorded oxidative stress resistance: decreased hydrogen peroxide C. albicans orf19.4892 ORF TPK1 CAL0005520 PMID: 19391100|CGD_REF: CAL0122781 homozygous diploid, classical genetics null Not recorded osmotic stress resistance: decreased C. albicans orf19.4892 ORF TPK1 CAL0005520 PMID: 19391100|CGD_REF: CAL0122781 homozygous diploid, classical genetics null Not recorded chemical compound accumulation: decreased glycogen C. albicans orf19.4892 ORF TPK1 CAL0005520 PMID: 21407800|CGD_REF: CAL0141800 homozygous diploid, classical genetics null BWP17 interaction with host/environment: abnormal significantly reduces adhesion, invasion, and damage to epithelial cells ex vivo model of infection C. albicans orf19.4892 ORF TPK1 CAL0005520 PMID: 15760450|CGD_REF: CAL0104038 heterozygous diploid, classical genetics null Not recorded virulence: normal fungal load is slightly decreased at early timepoints mouse oropharyngeal infection C. albicans orf19.4892 ORF TPK1 CAL0005520 PMID: 15760450|CGD_REF: CAL0104038 homozygous diploid, classical genetics null Not recorded virulence: normal fungal load is slightly decreased at early timepoints mouse oropharyngeal infection C. albicans orf19.4892 ORF TPK1 CAL0005520 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient YPD medium C. albicans orf19.4893 ORF CAL0005521 PMID: 14663094|CGD_REF: CAL0080633 homozygous diploid, systematic mutation set (homozygous insertion mutants generated with URA3-ARG4-URA3 (UAU1) cassette) null BWP17 viable C. albicans orf19.4897 ORF SFH5 CAL0005528 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.4898 ORF CAL0005529 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.4899 ORF GCA1 CAL0005531 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.4899 ORF GCA1 CAL0005531 PMID: 19529758|CGD_REF: CAL0123764 heterozygous diploid, classical genetics overexpression BWP17 biofilm formation: abnormal C. albicans orf19.4900 ORF MNN12 CAL0006195 PMID: 23886038|CGD_REF: CAL0000172548 homozygous diploid, classical genetics null CAI-4 viable C. albicans orf19.4903 ORF CAL0006198 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.4904 ORF CAL0006200 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.4905 ORF CAL0006202 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.4905 ORF CAL0006202 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: decreased growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.4905 ORF CAL0006202 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.4905 ORF CAL0006202 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.4905 ORF CAL0006202 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.4906 ORF CAL0006203 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.4906 ORF CAL0006203 PMID: 20384695|CGD_REF: CAL0125373 homozygous diploid, classical genetics null BWP17 viable C. albicans orf19.4907 ORF CAL0006205 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.4909 ORF CBK1 CAL0006211 PMID: 11889116|CGD_REF: CAL0080824 homozygous diploid, classical genetics null Not recorded flocculation: increased liquid Lee's medium at 30 or 37 deg C, and various other media C. albicans orf19.4909 ORF CBK1 CAL0006211 PMID: 18843050|CGD_REF: CAL0120345 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased Calcofluor White C. albicans orf19.4909 ORF CBK1 CAL0006211 PMID: 18843050|CGD_REF: CAL0120345 heterozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased itraconazole sensitivity is intermediate between that of the homozygous null mutant and wild type C. albicans orf19.4909 ORF CBK1 CAL0006211 PMID: 18843050|CGD_REF: CAL0120345 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased itraconazole C. albicans orf19.4909 ORF CBK1 CAL0006211 PMID: 18843050|CGD_REF: CAL0120345 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased sodium dodecyl sulfate C. albicans orf19.4909 ORF CBK1 CAL0006211 PMID: 18843050|CGD_REF: CAL0120345 homozygous diploid, classical genetics null Not recorded vegetative growth: decreased rate C. albicans orf19.4909 ORF CBK1 CAL0006211 PMID: 12773383|CGD_REF: CAL0087974 heterozygous diploid, classical genetics (haploinsufficient phenotype assay) null CAI-4 viable heterozygous deletion C. albicans orf19.4909 ORF CBK1 CAL0006211 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.4909 ORF CBK1 CAL0006211 PMID: 18843050|CGD_REF: CAL0120345 heterozygous diploid, classical genetics null Not recorded viable URA3-blaster technique C. albicans orf19.4909 ORF CBK1 CAL0006211 PMID: 18843050|CGD_REF: CAL0120345 homozygous diploid, classical genetics null Not recorded viable URA3-blaster technique C. albicans orf19.4909 ORF CBK1 CAL0006211 PMID: 11889116|CGD_REF: CAL0080824 heterozygous diploid, classical genetics null Not recorded viable C. albicans orf19.4909 ORF CBK1 CAL0006211 PMID: 11889116|CGD_REF: CAL0080824 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.4909 ORF CBK1 CAL0006211 PMID: 18843050|CGD_REF: CAL0120345 homozygous diploid, classical genetics null Not recorded actin cytoskeleton morphology: abnormal defect in polarization of cortical actin patches in both yeast-form and hyphal cells C. albicans orf19.4909 ORF CBK1 CAL0006211 PMID: 18843050|CGD_REF: CAL0120345 homozygous diploid, classical genetics null Not recorded actin cytoskeleton morphology: abnormal defect in polarization of cortical actin patches, in both yeast-form and hyphal cells C. albicans orf19.4909 ORF CBK1 CAL0006211 PMID: 11889116|CGD_REF: CAL0080824 homozygous diploid, classical genetics null Not recorded hyphal growth: absent all liquid or solid media tested, 30 or 37 deg C C. albicans orf19.4909 ORF CBK1 CAL0006211 PMID: 11889116|CGD_REF: CAL0080824 heterozygous diploid, classical genetics null Not recorded hyphal growth: decreased solid Spider, Lee's, or M199 ph 7.0 media C. albicans orf19.4909 ORF CBK1 CAL0006211 PMID: 18843050|CGD_REF: CAL0120345 homozygous diploid, classical genetics null CAI-4 hyphal growth: decreased solid and liquid media C. albicans orf19.4909 ORF CBK1 CAL0006211 PMID: 18843050|CGD_REF: CAL0120345 homozygous diploid, classical genetics null Not recorded cell cycle progression: abnormal cells are multinucleate C. albicans orf19.4909 ORF CBK1 CAL0006211 PMID: 18843050|CGD_REF: CAL0120345 homozygous diploid, classical genetics null Not recorded cell shape: abnormal cells are round and enlarged C. albicans orf19.4909 ORF CBK1 CAL0006211 PMID: 18843050|CGD_REF: CAL0120345 homozygous diploid, classical genetics null Not recorded hypoosmotic stress resistance: decreased cells lyse in liquid YPD C. albicans orf19.4909 ORF CBK1 CAL0006211 PMID: 18843050|CGD_REF: CAL0120345 homozygous diploid, classical genetics null Not recorded cell size: increased cells are round, large, and heterogeneous in size C. albicans orf19.4909 ORF CBK1 CAL0006211 PMID: 18843050|CGD_REF: CAL0120345 homozygous diploid, classical genetics null Not recorded cytokinesis: absent C. albicans orf19.4909 ORF CBK1 CAL0006211 PMID: 18843050|CGD_REF: CAL0120345 homozygous diploid, classical genetics null Not recorded plasma membrane morphology: abnormal lack of polarized lipid domains (lipid rafts) C. albicans orf19.4909 ORF CBK1 CAL0006211 PMID: 11889116|CGD_REF: CAL0080824 heterozygous diploid, classical genetics null Not recorded pseudohyphal growth: increased C. albicans orf19.4909 ORF CBK1 CAL0006211 PMID: 18843050|CGD_REF: CAL0120345 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased Congo Red C. albicans orf19.4909 ORF CBK1 CAL0006211 PMID: 12773383|CGD_REF: CAL0087974 heterozygous diploid, classical genetics (haploinsufficient phenotype assay) null CAI-4 filamentous growth: decreased solid Spider medium heterozygous deletion C. albicans orf19.4909 ORF CBK1 CAL0006211 PMID: 12773383|CGD_REF: CAL0087974 heterozygous diploid, classical genetics (haploinsufficient phenotype assay) unspecified CAI-4 filamentous growth: decreased solid Spider medium heterozygous transposon insertion C. albicans orf19.4909 ORF CBK1 CAL0006211 PMID: 18843050|CGD_REF: CAL0120345 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased Hygromycin B C. albicans orf19.4909 ORF CBK1 CAL0006211 PMID: 18843050|CGD_REF: CAL0120345 heterozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased fluconazole sensitivity is intermediate between that of the homozygous null mutant and wild type C. albicans orf19.4909 ORF CBK1 CAL0006211 PMID: 18843050|CGD_REF: CAL0120345 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased fluconazole C. albicans orf19.4909 ORF CBK1 CAL0006211 PMID: 21375589|CGD_REF: CAL0141772 homozygous diploid, classical genetics null CAF2-1 resistance to chemicals: decreased tunicamycin C. albicans orf19.4909 ORF CBK1 CAL0006211 PMID: 22589718|CGD_REF: CAL0000157315 homozygous diploid, classical genetics null BWP17 biofilm formation: decreased C. albicans orf19.4909 ORF CBK1 CAL0006211 PMID: 20140194|CGD_REF: CAL0124995 homozygous diploid, classical genetics null Other C. albicans resistance to chemicals: decreased caspofungin C. albicans orf19.4909 ORF CBK1 CAL0006211 PMID: 20140194|CGD_REF: CAL0124995 homozygous diploid, classical genetics null Other C. albicans viable caspofungin C. albicans orf19.4909 ORF CBK1 CAL0006211 PMID: 20140194|CGD_REF: CAL0124995 homozygous diploid, classical genetics null Other C. albicans viable C. albicans orf19.491 ORF CAL0005862 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.4910 ORF FGR41 CAL0006224 PMID: 12773383|CGD_REF: CAL0087974 heterozygous diploid, classical genetics (haploinsufficient phenotype assay) unspecified CAI-4 filamentous growth: decreased solid Spider medium or solid YEPD plus serum transposon insertion proximal to, but not within, the ORF C. albicans orf19.4916 ORF CAL0006231 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.4916 ORF CAL0006231 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.4916 ORF CAL0006231 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.4916 ORF CAL0006231 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.4916 ORF CAL0006231 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.4918 ORF CAL0006236 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.4919 ORF CAL0006239 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.4921 ORF CAL0006251 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.4923 ORF CAL0006253 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.4927 ORF BNI1 CAL0006256 PMID: 16855023|CGD_REF: CAL0116679 homozygous diploid, classical genetics null Not recorded vesicle distribution: abnormal specific defect in Golgi localization to the hyphal tip C. albicans orf19.4927 ORF BNI1 CAL0006256 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.4927 ORF BNI1 CAL0006256 PMID: 16215178|CGD_REF: CAL0114839 heterozygous diploid, classical genetics repressible Not recorded viable depletion causes same phenotypes as homozygous null mutation C. albicans orf19.4927 ORF BNI1 CAL0006256 PMID: 15914538|CGD_REF: CAL0114281 heterozygous diploid, classical genetics null Not recorded viable C. albicans orf19.4927 ORF BNI1 CAL0006256 PMID: 15914538|CGD_REF: CAL0114281 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.4927 ORF BNI1 CAL0006256 PMID: 16215178|CGD_REF: CAL0114839 heterozygous diploid, classical genetics null Not recorded viable C. albicans orf19.4927 ORF BNI1 CAL0006256 PMID: 16215178|CGD_REF: CAL0114839 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.4927 ORF BNI1 CAL0006256 PMID: 15914538|CGD_REF: CAL0114281 homozygous diploid, classical genetics null Not recorded protein/peptide distribution: abnormal Kar9p C. albicans orf19.4927 ORF BNI1 CAL0006256 PMID: 15914538|CGD_REF: CAL0114281 homozygous diploid, classical genetics null Not recorded actin cytoskeleton morphology: abnormal actin patches are delocalized in yeast-form cells, but actin localization is relatively wild-type in hyphae C. albicans orf19.4927 ORF BNI1 CAL0006256 PMID: 16215178|CGD_REF: CAL0114839 homozygous diploid, classical genetics null Not recorded actin cytoskeleton morphology: abnormal defect in actin patch polarity; delocalization of patches from bud to mother cell C. albicans orf19.4927 ORF BNI1 CAL0006256 PMID: 15914538|CGD_REF: CAL0114281 homozygous diploid, classical genetics null Not recorded hyphal growth: abnormal hyphae and germ tubes are swollen and contain multiple microtubule bundles C. albicans orf19.4927 ORF BNI1 CAL0006256 PMID: 16855023|CGD_REF: CAL0116679 homozygous diploid, classical genetics null BWP17 hyphal growth: abnormal specific defect in Golgi localization in hyphae C. albicans orf19.4927 ORF BNI1 CAL0006256 PMID: 15914538|CGD_REF: CAL0114281 homozygous diploid, classical genetics null BWP17 hyphal growth: abnormal swollen germ tubes and hyphae containing multiple microtubule bundles C. albicans orf19.4927 ORF BNI1 CAL0006256 PMID: 16215178|CGD_REF: CAL0114839 homozygous diploid, classical genetics null Not recorded bud neck morphology: abnormal bud necks are enlarged C. albicans orf19.4927 ORF BNI1 CAL0006256 PMID: 15914538|CGD_REF: CAL0114281 homozygous diploid, classical genetics null Not recorded budding pattern: abnormal bud site selection is more random than in wild type C. albicans orf19.4927 ORF BNI1 CAL0006256 PMID: 16215178|CGD_REF: CAL0114839 homozygous diploid, classical genetics null Not recorded budding pattern: abnormal bud site selection is more random than in wild type C. albicans orf19.4927 ORF BNI1 CAL0006256 PMID: 16215178|CGD_REF: CAL0114839 homozygous diploid, classical genetics null Not recorded cell size: increased cells are round and enlarged C. albicans orf19.4927 ORF BNI1 CAL0006256 PMID: 15914538|CGD_REF: CAL0114281 homozygous diploid, classical genetics null Not recorded cell size: increased cells are round and enlarged with an enlarged mother-bud neck; multinucleate cells observed C. albicans orf19.4927 ORF BNI1 CAL0006256 PMID: 16215178|CGD_REF: CAL0114839 homozygous diploid, classical genetics null Not recorded endomembrane system morphology: abnormal Spitzenkorper is enlarged C. albicans orf19.4927 ORF BNI1 CAL0006256 PMID: 15914538|CGD_REF: CAL0114281 homozygous diploid, classical genetics null BWP17 filamentous growth: abnormal solid ammonium sulfate medium does not display filamentous growth defect on all solid media C. albicans orf19.4927 ORF BNI1 CAL0006256 PMID: 16215178|CGD_REF: CAL0114839 homozygous diploid, classical genetics null BWP17 filamentous growth: decreased solid Spider medium C. albicans orf19.4927 ORF BNI1 CAL0006256 PMID: 15914538|CGD_REF: CAL0114281 homozygous diploid, classical genetics null Not recorded virulence: decreased exhibits decreased filamentous growth in kidneys mouse intravenous infection C. albicans orf19.4928 ORF SEC2 CAL0006259 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.4928 ORF SEC2 CAL0006259 PMID: 20639857|CGD_REF: CAL0125973 heterozygous diploid, classical genetics reduction of function SEC2(1-591)-YFP:URA3/sec2::HIS1 BWP17 hyphal growth: normal C. albicans orf19.4928 ORF SEC2 CAL0006259 PMID: 20639857|CGD_REF: CAL0125973 heterozygous diploid, classical genetics null SEC2/SEC2(1-508)-YFP:URA3 BWP17 inviable C. albicans orf19.4928 ORF SEC2 CAL0006259 PMID: 20639857|CGD_REF: CAL0125973 heterozygous diploid, classical genetics reduction of function SEC2(1-583)-YFP:URA3/sec2::HIS1 BWP17 hyphal growth: abnormal mutant unable to form normal hyphae C. albicans orf19.4930 ORF SPC3 CAL0006274 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.4930 ORF SPC3 CAL0006274 PMID: 15300682|CGD_REF: CAL0082073 heterozygous diploid, classical genetics null Not recorded viable C. albicans orf19.4930 ORF SPC3 CAL0006274 PMID: 15300682|CGD_REF: CAL0082073 homozygous diploid, classical genetics null Not recorded inviable homozygous null mutant strain could not be recovered, suggesting that the gene is essential under the selection conditions C. albicans orf19.4930 ORF SPC3 CAL0006274 PMID: 15300682|CGD_REF: CAL0082073 heterozygous diploid, classical genetics repressible Not recorded inviable C. albicans orf19.4931 ORF CAL0006275 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.4932 ORF CAL0006276 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.4933 ORF FAD3 CAL0006277 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.4933 ORF FAD3 CAL0006277 PMID: 16622072|CGD_REF: CAL0115920 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.4933 ORF FAD3 CAL0006277 PMID: 16622072|CGD_REF: CAL0115920 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.4933 ORF FAD3 CAL0006277 PMID: 16622072|CGD_REF: CAL0115920 homozygous diploid, classical genetics null Not recorded chemical compound accumulation: abnormal polyunsaturated fatty acid abnormal polyunsaturated fatty acid composition C. albicans orf19.4933 ORF FAD3 CAL0006277 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: decreased growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.4933 ORF FAD3 CAL0006277 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: abnormal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.4933 ORF FAD3 CAL0006277 PMID: 23572557|CGD_REF: CAL0000158900 homozygous diploid, classical genetics null BWP17 adhesion: decreased Fluxion Bioflux 200, equipped with a microscope, was used for adherence analysis allowing a constant flow of cells through microfluidic channels C. albicans orf19.4933 ORF FAD3 CAL0006277 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.4933 ORF FAD3 CAL0006277 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.4934 ORF OP4 CAL0006278 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.4934 ORF OP4 CAL0006278 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.4934 ORF OP4 CAL0006278 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.4934 ORF OP4 CAL0006278 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.4936 ORF CAL0006281 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 invasive growth: decreased solid SLAD media C. albicans orf19.4937 ORF CHS3 CAL0006283 PMID: 7479842|CGD_REF: CAL0081019 heterozygous diploid, classical genetics null Not recorded germ tube formation: normal serum- or GlcNAc-containing media, or RPMI 1640 C. albicans orf19.4937 ORF CHS3 CAL0006283 PMID: 7479842|CGD_REF: CAL0081019 homozygous diploid, classical genetics null Not recorded germ tube formation: normal serum- or GlcNAc-containing media, or RPMI 1640 C. albicans orf19.4937 ORF CHS3 CAL0006283 PMID: 7479842|CGD_REF: CAL0081019 homozygous diploid, classical genetics null Not recorded resistance to enzymatic treatment: decreased beta-glucuronidase C. albicans orf19.4937 ORF CHS3 CAL0006283 PMID: 7479842|CGD_REF: CAL0081019 homozygous diploid, classical genetics null Not recorded resistance to chemicals: increased Calcofluor White C. albicans orf19.4937 ORF CHS3 CAL0006283 PMID: 7479842|CGD_REF: CAL0081019 heterozygous diploid, classical genetics null Not recorded resistance to chemicals: normal Calcofluor White C. albicans orf19.4937 ORF CHS3 CAL0006283 PMID: 8636047|CGD_REF: CAL0081006 homozygous diploid, classical genetics null Not recorded vegetative growth: decreased rate C. albicans orf19.4937 ORF CHS3 CAL0006283 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.4937 ORF CHS3 CAL0006283 PMID: 10439400|CGD_REF: CAL0081025 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.4937 ORF CHS3 CAL0006283 PMID: 7479842|CGD_REF: CAL0081019 heterozygous diploid, classical genetics null Not recorded viable C. albicans orf19.4937 ORF CHS3 CAL0006283 PMID: 7479842|CGD_REF: CAL0081019 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.4937 ORF CHS3 CAL0006283 PMID: 8636047|CGD_REF: CAL0081006 heterozygous diploid, classical genetics null Not recorded viable C. albicans orf19.4937 ORF CHS3 CAL0006283 PMID: 8636047|CGD_REF: CAL0081006 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.4937 ORF CHS3 CAL0006283 PMID: 19154328|CGD_REF: CAL0122236 homozygous diploid, classical genetics null Other C. albicans hyphal growth: abnormal semisolid substrate increased oscillatory amplitude of hyphal tip oscillation C. albicans orf19.4937 ORF CHS3 CAL0006283 PMID: 15470104|CGD_REF: CAL0082131 homozygous diploid, classical genetics null CAI-4 hyphal growth: normal solid serum-containing medium C. albicans orf19.4937 ORF CHS3 CAL0006283 PMID: 7479842|CGD_REF: CAL0081019 homozygous diploid, classical genetics null Not recorded bud neck morphology: abnormal bud necks are enlarged; cells tend to aggregate C. albicans orf19.4937 ORF CHS3 CAL0006283 PMID: 8636047|CGD_REF: CAL0081006 homozygous diploid, classical genetics null Not recorded cell size: increased swollen morphology is rescued by sorbitol C. albicans orf19.4937 ORF CHS3 CAL0006283 PMID: 8636047|CGD_REF: CAL0081006 heterozygous diploid, classical genetics null Not recorded cell wall morphology: normal chitin content is normal C. albicans orf19.4937 ORF CHS3 CAL0006283 PMID: 9493376|CGD_REF: CAL0081007 homozygous diploid, classical genetics null Not recorded cell wall morphology: abnormal C. albicans orf19.4937 ORF CHS3 CAL0006283 PMID: 8636047|CGD_REF: CAL0081006 homozygous diploid, classical genetics null Not recorded chitin deposition: decreased in both yeast-form and hyphal cells C. albicans orf19.4937 ORF CHS3 CAL0006283 PMID: 7479842|CGD_REF: CAL0081019 homozygous diploid, classical genetics null Not recorded chitin deposition: abnormal mutant shows no bud scars C. albicans orf19.4937 ORF CHS3 CAL0006283 PMID: 10439400|CGD_REF: CAL0081025 homozygous diploid, classical genetics null Not recorded chitin deposition: abnormal reduced cell wall chitin content C. albicans orf19.4937 ORF CHS3 CAL0006283 PMID: 17971081|CGD_REF: CAL0118713 homozygous diploid, classical genetics null Not recorded chitin deposition: abnormal short-chitin microfibrils are absent C. albicans orf19.4937 ORF CHS3 CAL0006283 PMID: 7479842|CGD_REF: CAL0081019 heterozygous diploid, classical genetics null Not recorded virulence: decreased immunosuppressed mouse intravenous infection C. albicans orf19.4937 ORF CHS3 CAL0006283 PMID: 7479842|CGD_REF: CAL0081019 homozygous diploid, classical genetics null Not recorded virulence: decreased immunosuppressed mouse intravenous infection C. albicans orf19.4937 ORF CHS3 CAL0006283 PMID: 7479842|CGD_REF: CAL0081019 heterozygous diploid, classical genetics null Not recorded virulence: decreased mouse intravenous infection C. albicans orf19.4937 ORF CHS3 CAL0006283 PMID: 7479842|CGD_REF: CAL0081019 homozygous diploid, classical genetics null Not recorded virulence: decreased mouse intravenous infection C. albicans orf19.4937 ORF CHS3 CAL0006283 PMID: 8636047|CGD_REF: CAL0081006 homozygous diploid, classical genetics null Not recorded virulence: normal mouse intravenous infection C. albicans orf19.4937 ORF CHS3 CAL0006283 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient YPD medium C. albicans orf19.494 ORF CAL0005870 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.4940 ORF CAL0006299 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.4941 ORF TYE7 CAL0006300 PMID: 20041210|CGD_REF: CAL0124764 homozygous diploid, systematic mutation set null SN152 colony color: abnormal CHROMagar medium at 37 deg C darker than normal C. albicans orf19.4941 ORF TYE7 CAL0006300 PMID: 21414038|CGD_REF: CAL0141808 homozygous diploid, classical genetics null BWP17 filamentous growth: increased increased filametous growth when grown under hypoxic conditions; not observed when these strains were grown under normoxia at 30 or 37 degrees C C. albicans orf19.4941 ORF TYE7 CAL0006300 PMID: 21414038|CGD_REF: CAL0141808 homozygous diploid, classical genetics null BWP17 biofilm formation: decreased decreased biofilm adherence, easy to detach from the plastic surface C. albicans orf19.4941 ORF TYE7 CAL0006300 PMID: 21414038|CGD_REF: CAL0141808 homozygous diploid, classical genetics null BWP17 viable C. albicans orf19.4941 ORF TYE7 CAL0006300 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.4941 ORF TYE7 CAL0006300 PMID: 21414038|CGD_REF: CAL0141808 homozygous diploid, classical genetics null BWP17 viable Tye7 null has increased doubling times relative to twild-type controls grown under low aeration (SD 0.4% glucose at 37 degrees C in microtiter plates, under strong aeration in the presence ofantimycin A and in an anaerobic atmosphere on YPD solid medium at 37 degrees C C. albicans orf19.4941 ORF TYE7 CAL0006300 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.4941 ORF TYE7 CAL0006300 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.4941 ORF TYE7 CAL0006300 PMID: 23526879|CGD_REF: CAL0000158852 homozygous diploid, classical genetics null SN152 viable C. albicans orf19.4941 ORF TYE7 CAL0006300 PMID: 23526879|CGD_REF: CAL0000158852 homozygous diploid, classical genetics null SN152 virulence: decreased significant defect in GI tract colonization mouse gastrointestinal tract infection C. albicans orf19.4941 ORF TYE7 CAL0006300 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.4943 ORF PSA2 CAL0006302 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.4943 ORF PSA2 CAL0006302 PMID: 19187560|CGD_REF: CAL0122338 homozygous diploid, classical genetics null SC5314 biofilm formation: abnormal forms biofilm with altered detachment properties C. albicans orf19.4945 ORF MSH6 CAL0006305 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.4948 ORF REX3 CAL0006310 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.4950 ORF AKR1 CAL0006326 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.4952 ORF CAL0006328 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient YNB medium C. albicans orf19.4953 ORF CAL0006329 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.4954 ORF CAL0006331 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.4954 ORF CAL0006331 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 invasive growth: decreased solid SLAD media C. albicans orf19.4955 ORF CAL0006333 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 invasive growth: decreased solid SLAD media C. albicans orf19.4956 ORF RPN1 CAL0006334 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.4956 ORF RPN1 CAL0006334 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient YPD medium C. albicans orf19.4956 ORF RPN1 CAL0006334 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient SLAD medium C. albicans orf19.4958 ORF ECM25 CAL0006338 PMID: 18368314|CGD_REF: CAL0119034 homozygous diploid, classical genetics null Not recorded vegetative growth: decreased rate C. albicans orf19.4958 ORF ECM25 CAL0006338 PMID: 18368314|CGD_REF: CAL0119034 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.4958 ORF ECM25 CAL0006338 PMID: 18368314|CGD_REF: CAL0119034 homozygous diploid, classical genetics null BWP17 filamentous growth: decreased C. albicans orf19.4958 ORF ECM25 CAL0006338 PMID: 18368314|CGD_REF: CAL0119034 homozygous diploid, classical genetics null Not recorded virulence: decreased exhibits decreased kidney colonization mouse intravenous infection C. albicans orf19.496 ORF CAL0005874 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.4960 ORF CAL0006358 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.4961 ORF STP2 CAL0006359 PMID: 16227594|CGD_REF: CAL0114869 heterozygous diploid, classical genetics null Not recorded viable C. albicans orf19.4961 ORF STP2 CAL0006359 PMID: 16227594|CGD_REF: CAL0114869 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.4961 ORF STP2 CAL0006359 PMID: 16227594|CGD_REF: CAL0114869 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased sulfonylurea herbicide MM sensitivity indicates a defect in uptake of branched-chain amino acids C. albicans orf19.4961 ORF STP2 CAL0006359 PMID: 22365851|CGD_REF: CAL0000144076 homozygous diploid, classical genetics null SN95 filamentous growth: absent mutant did not filament in response to geldanamycin or elevated temperature (42 degrees C) C. albicans orf19.4961 ORF STP2 CAL0006359 PMID: 24626429|CGD_REF: CAL0000173806 homozygous diploid, classical genetics null SC5314 chemical compound excretion: decreased ammonia GM-BCP medium C. albicans orf19.4961 ORF STP2 CAL0006359 PMID: 24626429|CGD_REF: CAL0000173806 homozygous diploid, classical genetics null SC5314 nutrient utilization: abnormal decreased utilization of amino acids C. albicans orf19.4961 ORF STP2 CAL0006359 PMID: 24626429|CGD_REF: CAL0000173806 homozygous diploid, classical genetics null SC5314 resistance to phagocytosis: decreased C. albicans orf19.4961 ORF STP2 CAL0006359 PMID: 24626429|CGD_REF: CAL0000173806 homozygous diploid, classical genetics null SC5314 virulence: decreased mouse intravenous infection C. albicans orf19.4966 ORF AGC1 CAL0006367 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.4966 ORF AGC1 CAL0006367 PMID: 14663094|CGD_REF: CAL0080633 homozygous diploid, systematic mutation set (homozygous insertion mutants generated with URA3-ARG4-URA3 (UAU1) cassette) null BWP17 viable C. albicans orf19.4969 ORF KEM1 CAL0006374 PMID: 15183877|CGD_REF: CAL0082063 homozygous diploid, classical genetics null CAI-4 germ tube formation: decreased liquid Spider or Lee's media C. albicans orf19.4969 ORF KEM1 CAL0006374 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.4969 ORF KEM1 CAL0006374 PMID: 14663094|CGD_REF: CAL0080633 homozygous diploid, systematic mutation set (homozygous insertion mutants generated with URA3-ARG4-URA3 (UAU1) cassette) null BWP17 viable C. albicans orf19.4969 ORF KEM1 CAL0006374 PMID: 15183877|CGD_REF: CAL0082063 homozygous diploid, classical genetics null CAI-4 hyphal growth: decreased solid serum-containing medium slight decrease C. albicans orf19.4969 ORF KEM1 CAL0006374 PMID: 15183877|CGD_REF: CAL0082063 heterozygous diploid, classical genetics null CAI-4 hyphal growth: decreased solid Spider or Lee's media C. albicans orf19.4969 ORF KEM1 CAL0006374 PMID: 15183877|CGD_REF: CAL0082063 homozygous diploid, classical genetics null CAI-4 hyphal growth: decreased solid Spider or Lee's media C. albicans orf19.4969 ORF KEM1 CAL0006374 PMID: 16087754|CGD_REF: CAL0114512 homozygous diploid, classical genetics null BWP17 hyphal growth: absent M199 pH 8 and Spider media C. albicans orf19.4969 ORF KEM1 CAL0006374 PMID: 15813744|CGD_REF: CAL0104042 homozygous diploid, classical genetics null Not recorded resistance to chemicals: increased fluconazole C. albicans orf19.4969 ORF KEM1 CAL0006374 PMID: 16087754|CGD_REF: CAL0114512 homozygous diploid, classical genetics null BWP17 biofilm formation: decreased C. albicans orf19.4969 ORF KEM1 CAL0006374 PMID: 20223293|CGD_REF: CAL0125139 homozygous diploid, classical genetics null BWP17 virulence: decreased G. mellonella infection insect infection C. albicans orf19.4969 ORF KEM1 CAL0006374 PMID: 20571955|CGD_REF: CAL0125847 homozygous diploid, classical genetics null SC5314 viable C. albicans orf19.4969 ORF KEM1 CAL0006374 PMID: 20571955|CGD_REF: CAL0125847 homozygous diploid, classical genetics null SC5314 resistance to killing by host cells: decreased RAW264.7 macrophages in vitro model of infection C. albicans orf19.4969 ORF KEM1 CAL0006374 PMID: 20571955|CGD_REF: CAL0125847 homozygous diploid, classical genetics null SC5314 protein/peptide accumulation: decreased Lpd1p C. albicans orf19.4969 ORF KEM1 CAL0006374 PMID: 20571955|CGD_REF: CAL0125847 homozygous diploid, classical genetics null SC5314 protein/peptide accumulation: decreased Met6p C. albicans orf19.4969 ORF KEM1 CAL0006374 PMID: 20571955|CGD_REF: CAL0125847 homozygous diploid, classical genetics null SC5314 protein/peptide accumulation: increased Idh1p C. albicans orf19.4969 ORF KEM1 CAL0006374 PMID: 20571955|CGD_REF: CAL0125847 homozygous diploid, classical genetics null SC5314 protein/peptide accumulation: increased Idh2p C. albicans orf19.4969 ORF KEM1 CAL0006374 PMID: 20571955|CGD_REF: CAL0125847 homozygous diploid, classical genetics null SC5314 protein/peptide accumulation: increased Ssb1p C. albicans orf19.4969 ORF KEM1 CAL0006374 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 invasive growth: decreased solid SLAD media C. albicans orf19.497 ORF EAF7 CAL0005877 PMID: 18685084|CGD_REF: CAL0119364 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.4972 ORF CAL0006395 PMID: 15964282|CGD_REF: CAL0114274 homozygous diploid, systematic mutation set (split-marker transposon insertion strategy to disrupt both alleles) null BWP17 viable C. albicans orf19.4972 ORF CAL0006395 PMID: 17880264|CGD_REF: CAL0118619 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.4972 ORF CAL0006395 PMID: 19463063|CGD_REF: CAL0123630 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.4972 ORF CAL0006395 PMID: 15964282|CGD_REF: CAL0114274 homozygous diploid, systematic mutation set (split-marker transposon insertion strategy to disrupt both alleles) null BWP17 biofilm formation: normal C. albicans orf19.4972 ORF CAL0006395 PMID: 17880264|CGD_REF: CAL0118619 homozygous diploid, classical genetics null Not recorded phenotypic switching: normal MTLa/MTLa background white-to-opaque switching C. albicans orf19.4972 ORF CAL0006395 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.4972 ORF CAL0006395 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: abnormal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.4972 ORF CAL0006395 PMID: 19463063|CGD_REF: CAL0123630 homozygous diploid, systematic mutation set (split-marker transposon insertion strategy to disrupt both alleles) null BWP17 virulence: normal Toll mutant D. melanogaster invasive infection insect infection C. albicans orf19.4972 ORF CAL0006395 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.4972 ORF CAL0006395 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.4975 ORF HYR1 CAL0006398 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.4975 ORF HYR1 CAL0006398 PMID: 21283544|CGD_REF: CAL0141430 homozygous diploid, classical genetics null Other C. albicans biofilm formation: decreased mouse oropharyngeal infection C. albicans orf19.4975 ORF HYR1 CAL0006398 PMID: 8808922|CGD_REF: CAL0081439 unknown ploidy, classical genetics misexpression CAI-4 viable no apparent phenotype C. albicans orf19.4975 ORF HYR1 CAL0006398 PMID: 8808922|CGD_REF: CAL0081439 unknown ploidy, classical genetics misexpression CAI-4 cellular morphology: normal C. albicans orf19.4975 ORF HYR1 CAL0006398 PMID: 8808922|CGD_REF: CAL0081439 unknown ploidy, classical genetics misexpression CAI-4 resistance to chemicals: normal Calcofluor White|caffeine C. albicans orf19.4975 ORF HYR1 CAL0006398 PMID: 8808922|CGD_REF: CAL0081439 homozygous diploid, classical genetics null CAI-4 resistance to chemicals: normal Calcofluor White|caffeine C. albicans orf19.4975 ORF HYR1 CAL0006398 PMID: 8808922|CGD_REF: CAL0081439 homozygous diploid, classical genetics null CAI-4 viable no apparent phenotype C. albicans orf19.4975 ORF HYR1 CAL0006398 PMID: 18765290|CGD_REF: CAL0119430 homozygous diploid, classical genetics null BWP17 viable C. albicans orf19.4975 ORF HYR1 CAL0006398 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.4975 ORF HYR1 CAL0006398 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.4975 ORF HYR1 CAL0006398 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.4975 ORF HYR1 CAL0006398 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.4979 ORF KNS1 CAL0006406 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.4979 ORF KNS1 CAL0006406 PMID: 14663094|CGD_REF: CAL0080633 homozygous diploid, systematic mutation set (homozygous insertion mutants generated with URA3-ARG4-URA3 (UAU1) cassette) null BWP17 viable C. albicans orf19.4980 ORF HSP70 CAL0000006 PMID: 16720580|CGD_REF: CAL0116423 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.4980 ORF HSP70 CAL0000006 PMID: 21085601|CGD_REF: CAL0139856 homozygous diploid, classical genetics null hsp70 (ssa1::FRTssa1::FRT) SC5314 interaction with host/environment: decreased mutant grew only in small foci and caused little visible epithelial cell damage C. albicans orf19.4980 ORF HSP70 CAL0000006 PMID: 21085601|CGD_REF: CAL0139856 homozygous diploid, classical genetics null SC5314 virulence: decreased male BALB/c mice mouse oropharyngeal infection (immunosuppressed with cortisone acetate) C. albicans orf19.4980 ORF HSP70 CAL0000006 PMID: 21085601|CGD_REF: CAL0139856 homozygous diploid, classical genetics null SC5314 virulence: decreased 20 g male BALB/c mice mouse intravenous infection C. albicans orf19.4981 ORF CAL0000007 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.4981 ORF CAL0000007 PMID: 17873081|CGD_REF: CAL0118685 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.4981 ORF CAL0000007 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 invasive growth: decreased solid SLAD media C. albicans orf19.4982 ORF CAL0000008 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.4982 ORF CAL0000008 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.4982 ORF CAL0000008 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.4982 ORF CAL0000008 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.4984 ORF CAL0000011 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.4984 ORF CAL0000011 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.4984 ORF CAL0000011 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.4984 ORF CAL0000011 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.4984 ORF CAL0000011 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.4985 ORF GUP1 CAL0000013 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.4985 ORF GUP1 CAL0000013 PMID: 19383674|CGD_REF: CAL0122777 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.4985 ORF GUP1 CAL0000013 PMID: 20843317|CGD_REF: CAL0126249 homozygous diploid, classical genetics null gup1::URA3-dpl200/gup1::ARG4 BWP17 resistance to chemicals: increased clotrimazole C. albicans orf19.4985 ORF GUP1 CAL0000013 PMID: 20843317|CGD_REF: CAL0126249 homozygous diploid, classical genetics null gup1::URA3-dpl200/gup1::ARG4 BWP17 resistance to chemicals: increased ketoconazole C. albicans orf19.4985 ORF GUP1 CAL0000013 PMID: 20843317|CGD_REF: CAL0126249 homozygous diploid, classical genetics null gup1::URA3-dpl200/gup1::ARG4 BWP17 resistance to chemicals: increased fluconazole C. albicans orf19.4985 ORF GUP1 CAL0000013 PMID: 20843317|CGD_REF: CAL0126249 homozygous diploid, classical genetics null gup1::URA3-dpl200/gup1::ARG4 BWP17 resistance to chemicals: increased fenpropimorph C. albicans orf19.4985 ORF GUP1 CAL0000013 PMID: 20843317|CGD_REF: CAL0126249 homozygous diploid, classical genetics null gup1::URA3-dpl200/gup1::ARG4 BWP17 hyphal growth: decreased C. albicans orf19.4985 ORF GUP1 CAL0000013 PMID: 20843317|CGD_REF: CAL0126249 homozygous diploid, classical genetics null gup1::URA3-dpl200/gup1::ARG4 BWP17 cell shape: abnormal C. albicans orf19.4985 ORF GUP1 CAL0000013 PMID: 20843317|CGD_REF: CAL0126249 homozygous diploid, classical genetics null gup1::URA3-dpl200/gup1::ARG4 BWP17 adhesion: decreased reduced adhesion to polystyrene C. albicans orf19.4985 ORF GUP1 CAL0000013 PMID: 20843317|CGD_REF: CAL0126249 homozygous diploid, classical genetics null gup1::URA3-dpl200/gup1::ARG4 BWP17 invasive growth: decreased C. albicans orf19.4985 ORF GUP1 CAL0000013 PMID: 20843317|CGD_REF: CAL0126249 homozygous diploid, classical genetics null gup1::URA3-dpl200/gup1::ARG4 BWP17 biofilm formation: decreased C. albicans orf19.4987 ORF NUP49 CAL0000016 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.4993 ORF SEC18 CAL0000029 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.4996 ORF CAL0000035 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.4998 ORF ROB1 CAL0000039 PMID: 20041210|CGD_REF: CAL0124764 homozygous diploid, systematic mutation set null SN152 invasive growth: decreased YEPD medium at 30 or 37 deg C strongly decreased C. albicans orf19.4998 ORF ROB1 CAL0000039 PMID: 20041210|CGD_REF: CAL0124764 homozygous diploid, systematic mutation set null SN152 colony appearance: abnormal Spider medium smooth colonies with no peripheral filamentation C. albicans orf19.4998 ORF ROB1 CAL0000039 PMID: 22073120|CGD_REF: CAL0000143592 homozygous diploid, classical genetics null BWP17 viable C. albicans orf19.4998 ORF ROB1 CAL0000039 PMID: 22073120|CGD_REF: CAL0000143592 homozygous diploid, classical genetics null BWP17 colony appearance: abnormal decreased colony wrinkling C. albicans orf19.4998 ORF ROB1 CAL0000039 PMID: 22073120|CGD_REF: CAL0000143592 homozygous diploid, classical genetics null BWP17 hyphal growth: decreased C. albicans orf19.4998 ORF ROB1 CAL0000039 PMID: 22265407|CGD_REF: CAL0000143925 homozygous diploid, classical genetics null Other C. albicans biofilm formation: decreased C. albicans orf19.4998 ORF ROB1 CAL0000039 PMID: 23637598|CGD_REF: CAL0000172002 homozygous diploid, classical genetics null a/a arg1::hisG/arg1::hisG rob1::HIS1/rob1::LEU2 P37005 biofilm formation: decreased 37 degrees C in Spider medium deficient in 10uM alpha pheromone stimulated biofilms C. albicans orf19.50 ORF CAL0000600 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.50 ORF CAL0000600 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.50 ORF CAL0000600 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.50 ORF CAL0000600 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.500 ORF CAL0000045 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.5000 ORF CYB2 CAL0001565 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.5001 ORF CUP2 CAL0001566 PMID: 14663094|CGD_REF: CAL0080633 homozygous diploid, systematic mutation set (homozygous insertion mutants generated with URA3-ARG4-URA3 (UAU1) cassette) null BWP17 viable C. albicans orf19.5001 ORF CUP2 CAL0001566 PMID: 20041210|CGD_REF: CAL0124764 homozygous diploid, systematic mutation set null SN152 metal resistance: decreased copper(2+) strongly sensitive C. albicans orf19.5001 ORF CUP2 CAL0001566 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.5001 ORF CUP2 CAL0001566 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.5001 ORF CUP2 CAL0001566 PMID: 8436951|CGD_REF: CAL0100462 homozygous diploid, classical genetics null Other C. albicans resistance to chemicals: decreased acetic acid C. albicans orf19.5001 ORF CUP2 CAL0001566 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.5001 ORF CUP2 CAL0001566 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.5004 ORF RAD54 CAL0001568 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.5004 ORF RAD54 CAL0001568 PMID: 21951709|CGD_REF: CAL0000143399 homozygous diploid, classical genetics null rad54::SAT1-FLP SC5314 viable C. albicans orf19.5004 ORF RAD54 CAL0001568 PMID: 21951709|CGD_REF: CAL0000143399 homozygous diploid, classical genetics null rad54::SAT1-FLP SC5314 cell cycle progression through the G2/M phase transition: absent mutant cells arrest in G2 phase of the cell cycle C. albicans orf19.5004 ORF RAD54 CAL0001568 PMID: 21951709|CGD_REF: CAL0000143399 homozygous diploid, classical genetics null rad54::SAT1-FLP SC5314 cellular morphology: abnormal 20% of cells exhibit an elongated morphology reminiscent of pseudohyphae C. albicans orf19.5004 ORF RAD54 CAL0001568 PMID: 21951709|CGD_REF: CAL0000143399 homozygous diploid, classical genetics null rad54::SAT1-FLP SC5314 nuclear morphology: abnormal C. albicans orf19.5004 ORF RAD54 CAL0001568 PMID: 21951709|CGD_REF: CAL0000143399 homozygous diploid, classical genetics null rad54::SAT1-FLP SC5314 colony size: decreased C. albicans orf19.5004 ORF RAD54 CAL0001568 PMID: 21951709|CGD_REF: CAL0000143399 homozygous diploid, classical genetics null rad54::SAT1-FLP SC5314 resistance to chemicals: normal fluconazole C. albicans orf19.5004 ORF RAD54 CAL0001568 PMID: 21951709|CGD_REF: CAL0000143399 homozygous diploid, classical genetics null rad54::SAT1-FLP SC5314 colony appearance: abnormal mutant colonies have wrinkled appearance whereas wild-type colonies are smooth C. albicans orf19.5005 ORF OSM2 CAL0001569 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.5005 ORF OSM2 CAL0001569 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 invasive growth: decreased solid SLAD media C. albicans orf19.5006 ORF GCV3 CAL0001570 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.5006.1 ORF CAF0007029 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.5007 ORF ACT1 CAL0001571 PMID: 19115836|CGD_REF: CAL0122036 heterozygous diploid, competitive growth (haploinsufficient phenotype assay, barcode deletion set) null SC5314 resistance to chemicals: decreased virgineone C. albicans orf19.5008.1 ORF DAD1 CAF0007030 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.5008.1 ORF DAD1 CAF0007030 PMID: 21549601|CGD_REF: CAL0142005 heterozygous diploid, classical genetics repressible BWP17 inviable repressible conditions (with tetracycline) Gene replacement and conditional expression (GRACE) C. albicans orf19.501 ORF CAL0000046 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.501 ORF CAL0000046 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient SLAD medium C. albicans orf19.5010 ORF DIM1 CAL0001590 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.5010 ORF DIM1 CAL0001590 PMID: 12524333|CGD_REF: CAL0080691 homozygous diploid, systematic mutation set (homozygous insertion mutants generated with URA3-ARG4-URA3 (UAU1) cassette) null BWP17 inviable homozygous null mutant strain could not be recovered, suggesting that the gene is essential under the selection conditions C. albicans orf19.5011 ORF KAR9 CAL0001591 PMID: 14663094|CGD_REF: CAL0080633 homozygous diploid, systematic mutation set (homozygous insertion mutants generated with URA3-ARG4-URA3 (UAU1) cassette) null BWP17 viable C. albicans orf19.5013 ORF AGM1 CAL0001593 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.5014 ORF CAL0001594 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.5014 ORF CAL0001594 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.5014 ORF CAL0001594 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.5014 ORF CAL0001594 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.5014 ORF CAL0001594 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.5015 ORF MYO2 CAL0001595 PMID: 12583918|CGD_REF: CAL0080653 homozygous diploid, classical genetics null Not recorded vegetative growth: decreased rate C. albicans orf19.5015 ORF MYO2 CAL0001595 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.5015 ORF MYO2 CAL0001595 PMID: 12583918|CGD_REF: CAL0080653 heterozygous diploid, classical genetics null Not recorded viable wild-type growth rate C. albicans orf19.5015 ORF MYO2 CAL0001595 PMID: 12583918|CGD_REF: CAL0080653 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.5015 ORF MYO2 CAL0001595 PMID: 12583918|CGD_REF: CAL0080653 homozygous diploid, classical genetics null Not recorded actin cytoskeleton morphology: abnormal abolished F-actin cytoskeletal polarity C. albicans orf19.5015 ORF MYO2 CAL0001595 PMID: 12583918|CGD_REF: CAL0080653 homozygous diploid, classical genetics null CAI-4 hyphal growth: absent liquid YPDU at 37 deg C C. albicans orf19.5015 ORF MYO2 CAL0001595 PMID: 12583918|CGD_REF: CAL0080653 heterozygous diploid, classical genetics null CAI-4 hyphal growth: normal liquid YPDU at 37 deg C C. albicans orf19.5015 ORF MYO2 CAL0001595 PMID: 12583918|CGD_REF: CAL0080653 homozygous diploid, classical genetics null Not recorded nuclear morphology: abnormal C. albicans orf19.5015 ORF MYO2 CAL0001595 PMID: 12583918|CGD_REF: CAL0080653 homozygous diploid, classical genetics null Not recorded nuclear position: abnormal C. albicans orf19.5015 ORF MYO2 CAL0001595 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient YPD medium C. albicans orf19.5015 ORF MYO2 CAL0001595 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient YNB medium C. albicans orf19.5015 ORF MYO2 CAL0001595 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient SLAD medium C. albicans orf19.5015 ORF MYO2 CAL0001595 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 invasive growth: decreased solid SLAD media C. albicans orf19.5016 ORF CAL0001596 PMID: 14663094|CGD_REF: CAL0080633 homozygous diploid, systematic mutation set (homozygous insertion mutants generated with URA3-ARG4-URA3 (UAU1) cassette) null BWP17 viable C. albicans orf19.5019 ORF CAL0001598 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 invasive growth: decreased solid SLAD media C. albicans orf19.5020 ORF CAL0001614 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.5020 ORF CAL0001614 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.5020 ORF CAL0001614 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.5020 ORF CAL0001614 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.5021 ORF PDX1 CAL0001615 PMID: 17254815|CGD_REF: CAL0118475 homozygous diploid, classical genetics null BWP17 germ tube formation: decreased C. albicans orf19.5021 ORF PDX1 CAL0001615 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.5021 ORF PDX1 CAL0001615 PMID: 17254815|CGD_REF: CAL0118475 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.5021 ORF PDX1 CAL0001615 PMID: 19707174|CGD_REF: CAL0124230 homozygous diploid, classical genetics null BWP17 biofilm formation: decreased assayed by safranin staining of exopolysaccharide matrix C. albicans orf19.5022 ORF CAL0001616 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.5023 ORF DAL7 CAL0001617 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.5023 ORF DAL7 CAL0001617 PMID: 14663094|CGD_REF: CAL0080633 homozygous diploid, systematic mutation set (homozygous insertion mutants generated with URA3-ARG4-URA3 (UAU1) cassette) null BWP17 viable C. albicans orf19.5024 ORF GND1 CAL0001618 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.5025 ORF MET3 CAL0001619 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.5025 ORF MET3 CAL0001619 PMID: 21414038|CGD_REF: CAL0141808 homozygous diploid, classical genetics null BWP17 viable C. albicans orf19.5025 ORF MET3 CAL0001619 PMID: 21414038|CGD_REF: CAL0141808 homozygous diploid, classical genetics null BWP17 biofilm formation: normal C. albicans orf19.5025 ORF MET3 CAL0001619 PMID: 23572557|CGD_REF: CAL0000158900 homozygous diploid, classical genetics null BWP17 adhesion: decreased Fluxion Bioflux 200, equipped with a microscope, was used for adherence analysis allowing a constant flow of cells through microfluidic channels C. albicans orf19.5025 ORF MET3 CAL0001619 PMID: 23572557|CGD_REF: CAL0000158900 homozygous diploid, classical genetics null BWP17 resistance to chemicals: increased fluconazole RPMI+MOPS+Histidine medium , 6 hours without shaking at 37 degrees C 24 hr fluconazole treatment in 96 well plates C. albicans orf19.5026 ORF CAL0001620 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.5026 ORF CAL0001620 PMID: 15964282|CGD_REF: CAL0114274 homozygous diploid, systematic mutation set (split-marker transposon insertion strategy to disrupt both alleles) null BWP17 viable C. albicans orf19.5026 ORF CAL0001620 PMID: 19463063|CGD_REF: CAL0123630 homozygous diploid, systematic mutation set (split-marker transposon insertion strategy to disrupt both alleles) null BWP17 viable C. albicans orf19.5026 ORF CAL0001620 PMID: 15964282|CGD_REF: CAL0114274 homozygous diploid, systematic mutation set (split-marker transposon insertion strategy to disrupt both alleles) null BWP17 biofilm formation: normal C. albicans orf19.5026 ORF CAL0001620 PMID: 19463063|CGD_REF: CAL0123630 homozygous diploid, systematic mutation set (split-marker transposon insertion strategy to disrupt both alleles) null BWP17 virulence: normal Toll mutant D. melanogaster invasive infection insect infection C. albicans orf19.5026 ORF CAL0001620 PMID: 19463063|CGD_REF: CAL0123630 homozygous diploid, classical genetics null BWP17 virulence: normal BALB/c mice mouse intravenous infection C. albicans orf19.5027 ORF LCB2 CAL0001621 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.5027 ORF LCB2 CAL0001621 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, competitive growth (haploinsufficient phenotype assay, barcode deletion set) null SC5314 resistance to chemicals: decreased Aureobasidin A C. albicans orf19.5029 ORF MODF CAL0001623 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.5031 ORF SSK1 CAL0001641 PMID: 15664927|CGD_REF: CAL0103935 homozygous diploid, classical genetics null Not recorded toxin resistance: decreased human defensin-1, HNP-1 C. albicans orf19.5031 ORF SSK1 CAL0001641 PMID: 14555484|CGD_REF: CAL0080739 homozygous diploid, classical genetics null Not recorded heat sensitivity: increased C. albicans orf19.5031 ORF SSK1 CAL0001641 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.5031 ORF SSK1 CAL0001641 PMID: 14507372|CGD_REF: CAL0088818 heterozygous diploid, large-scale survey (large-scale identification of essential genes by gene replacement and conditional expression (GRACE) method) repressible CAI-4 viable one allele is deleted and the other is placed under repressible Tet promoter C. albicans orf19.5031 ORF SSK1 CAL0001641 PMID: 14555484|CGD_REF: CAL0080739 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.5031 ORF SSK1 CAL0001641 PMID: 15664927|CGD_REF: CAL0103935 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.5031 ORF SSK1 CAL0001641 PMID: 10639412|CGD_REF: CAL0081941 heterozygous diploid, classical genetics null ssk1::hisG/SSK1 CAI-4 hyphal growth: decreased solid M199 at pH 7.5 or Spider media reduced radial hyphae; heterozygous mutant and reintegrant show intermediate phenotype between that of homozygous null mutant and wild type C. albicans orf19.5031 ORF SSK1 CAL0001641 PMID: 10639412|CGD_REF: CAL0081941 heterozygous diploid, classical genetics null ssk1::hisG/SSK1 CAI-4 invasive growth: normal solid SLAD, low nitrogen C. albicans orf19.5031 ORF SSK1 CAL0001641 PMID: 10639412|CGD_REF: CAL0081941 heterozygous diploid, classical genetics null ssk1::hisG/SSK1 CAI-4 viable C. albicans orf19.5031 ORF SSK1 CAL0001641 PMID: 10639412|CGD_REF: CAL0081941 heterozygous diploid, classical genetics null ssk1::hisG/SSK1 CAI-4 virulence: decreased virulence is intermediate between that of the homozygous null mutant and wild type mouse intravenous infection C. albicans orf19.5031 ORF SSK1 CAL0001641 PMID: 10639412|CGD_REF: CAL0081941 homozygous diploid, classical genetics null ssk1::hisG/ssk1::hisG-URA3-hisG CAI-4 flocculation: increased liquid M199 at pH 7.5 C. albicans orf19.5031 ORF SSK1 CAL0001641 PMID: 10639412|CGD_REF: CAL0081941 homozygous diploid, classical genetics null ssk1::hisG/ssk1::hisG-URA3-hisG CAI-4 germ tube formation: decreased solid M199 at pH 7.5 C. albicans orf19.5031 ORF SSK1 CAL0001641 PMID: 10639412|CGD_REF: CAL0081941 homozygous diploid, classical genetics null ssk1::hisG/ssk1::hisG-URA3-hisG CAI-4 hyphal growth: normal all liquid media tested C. albicans orf19.5031 ORF SSK1 CAL0001641 PMID: 10639412|CGD_REF: CAL0081941 homozygous diploid, classical genetics null ssk1::hisG/ssk1::hisG-URA3-hisG CAI-4 hyphal growth: decreased solid M199 at pH 7.5 or Spider media C. albicans orf19.5031 ORF SSK1 CAL0001641 PMID: 10639412|CGD_REF: CAL0081941 homozygous diploid, classical genetics null ssk1::hisG/ssk1::hisG-URA3-hisG CAI-4 hyphal growth: decreased solid M199 at pH 7.5 or Spider media C. albicans orf19.5031 ORF SSK1 CAL0001641 PMID: 10639412|CGD_REF: CAL0081941 homozygous diploid, classical genetics null ssk1::hisG/ssk1::hisG-URA3-hisG CAI-4 invasive growth: increased solid SLAD, low nitrogen C. albicans orf19.5031 ORF SSK1 CAL0001641 PMID: 10639412|CGD_REF: CAL0081941 homozygous diploid, classical genetics null ssk1::hisG/ssk1::hisG-URA3-hisG CAI-4 osmotic stress resistance: normal liquid or solid M199 pH 7.5 at 37 deg C, M199 pH 4.0 at 28 deg C C. albicans orf19.5031 ORF SSK1 CAL0001641 PMID: 10639412|CGD_REF: CAL0081941 homozygous diploid, classical genetics null ssk1::hisG/ssk1::hisG-URA3-hisG CAI-4 oxidative stress resistance: normal liquid or solid M199 pH 7.5 at 37 deg C, M199 pH 4.0 at 28 deg C C. albicans orf19.5031 ORF SSK1 CAL0001641 PMID: 10639412|CGD_REF: CAL0081941 homozygous diploid, classical genetics null ssk1::hisG/ssk1::hisG-URA3-hisG CAI-4 viable C. albicans orf19.5031 ORF SSK1 CAL0001641 PMID: 10639412|CGD_REF: CAL0081941 homozygous diploid, classical genetics null ssk1::hisG/ssk1::hisG-URA3-hisG CAI-4 virulence: absent mouse intravenous infection C. albicans orf19.5031 ORF SSK1 CAL0001641 PMID: 17038117|CGD_REF: CAL0116844 heterozygous diploid, classical genetics reduction of function ssk1-D556N Not recorded oxidative stress resistance: decreased hydrogen peroxide C. albicans orf19.5031 ORF SSK1 CAL0001641 PMID: 17038117|CGD_REF: CAL0116844 heterozygous diploid, classical genetics reduction of function ssk1-D556N Not recorded oxidative stress resistance: decreased tert-butyl hydroperoxide C. albicans orf19.5031 ORF SSK1 CAL0001641 PMID: 17664325|CGD_REF: CAL0118482 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased voriconazole C. albicans orf19.5031 ORF SSK1 CAL0001641 PMID: 14555484|CGD_REF: CAL0080739 homozygous diploid, classical genetics null Not recorded oxidative stress resistance: decreased hydrogen peroxide C. albicans orf19.5031 ORF SSK1 CAL0001641 PMID: 14555484|CGD_REF: CAL0080739 homozygous diploid, classical genetics null Not recorded oxidative stress resistance: decreased potassium superoxide C. albicans orf19.5031 ORF SSK1 CAL0001641 PMID: 14555484|CGD_REF: CAL0080739 homozygous diploid, classical genetics null Not recorded oxidative stress resistance: decreased tert-butyl hydroperoxide C. albicans orf19.5031 ORF SSK1 CAL0001641 PMID: 14555484|CGD_REF: CAL0080739 homozygous diploid, classical genetics null Not recorded oxidative stress resistance: decreased menadione C. albicans orf19.5031 ORF SSK1 CAL0001641 PMID: 19542310|CGD_REF: CAL0123805 homozygous diploid, classical genetics null RM1000 filamentous growth: increased hypoxic conditions C. albicans orf19.5031 ORF SSK1 CAL0001641 PMID: 17664325|CGD_REF: CAL0118482 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased fluconazole C. albicans orf19.5031 ORF SSK1 CAL0001641 PMID: 15664927|CGD_REF: CAL0103935 homozygous diploid, classical genetics null ssk1::hisG/ssk1::hisG-URA3-hisG CAI-4 resistance to killing by host cells: decreased approximately 43% of ssk1 mutants killed compared to 18-22% for wild-type controls in vitro model of infection (human PMNs) C. albicans orf19.5031 ORF SSK1 CAL0001641 PMID: 18616606|CGD_REF: CAL0119333 homozygous diploid, classical genetics null Not recorded virulence: decreased decreased colonization rat vaginal infection C. albicans orf19.5032 ORF SIM1 CAL0001642 PMID: 18001349|CGD_REF: CAL0118752 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.5032 ORF SIM1 CAL0001642 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient SLAD medium C. albicans orf19.5033 ORF CAL0001643 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.5034 ORF YBP1 CAL0001644 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.5034 ORF YBP1 CAL0001644 PMID: 23706023|CGD_REF: CAL0000172371 homozygous diploid, classical genetics null Other C. albicans viable C. albicans orf19.5034 ORF YBP1 CAL0001644 PMID: 23706023|CGD_REF: CAL0000172371 homozygous diploid, classical genetics null Other C. albicans oxidative stress resistance: decreased hydrogen peroxide C. albicans orf19.5034 ORF YBP1 CAL0001644 PMID: 23706023|CGD_REF: CAL0000172371 homozygous diploid, classical genetics null Other C. albicans virulence: normal mouse intravenous infection C. albicans orf19.5034 ORF YBP1 CAL0001644 PMID: 23706023|CGD_REF: CAL0000172371 homozygous diploid, classical genetics null Other C. albicans virulence: decreased insect infection (Galleria mellonella survival model) C. albicans orf19.5037 ORF HRQ2 CAL0001647 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.5037 ORF HRQ2 CAL0001647 PMID: 14663094|CGD_REF: CAL0080633 homozygous diploid, systematic mutation set (homozygous insertion mutants generated with URA3-ARG4-URA3 (UAU1) cassette) null BWP17 viable C. albicans orf19.5038 ORF CAL0001648 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.5038 ORF CAL0001648 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient SC medium C. albicans orf19.5038 ORF CAL0001648 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient YNB medium C. albicans orf19.5038 ORF CAL0001648 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient SLAD medium C. albicans orf19.5039 ORF RRP42 CAL0001650 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.504 ORF CAL0000047 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.5040 ORF CAL0001665 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.5043 ORF CAL0001668 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.5043 ORF CAL0001668 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 invasive growth: decreased solid SLAD media C. albicans orf19.5046 ORF RAM1 CAL0001670 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.505 ORF SRV2 CAL0000048 PMID: 11325951|CGD_REF: CAL0081430 homozygous diploid, classical genetics null Not recorded germ tube formation: abnormal liquid serum-containing medium germ tube length is decreased C. albicans orf19.505 ORF SRV2 CAL0000048 PMID: 11325951|CGD_REF: CAL0081430 homozygous diploid, classical genetics null Not recorded germ tube formation: decreased various liquid media C. albicans orf19.505 ORF SRV2 CAL0000048 PMID: 14506030|CGD_REF: CAL0080817 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased fenpropimorph C. albicans orf19.505 ORF SRV2 CAL0000048 PMID: 14506030|CGD_REF: CAL0080817 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased itraconazole C. albicans orf19.505 ORF SRV2 CAL0000048 PMID: 14506030|CGD_REF: CAL0080817 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased miconazole C. albicans orf19.505 ORF SRV2 CAL0000048 PMID: 11325951|CGD_REF: CAL0081430 homozygous diploid, classical genetics null Not recorded vegetative growth: decreased rate liquid minimal medium (YNB) but not rich medium (YPD) C. albicans orf19.505 ORF SRV2 CAL0000048 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.505 ORF SRV2 CAL0000048 PMID: 11325951|CGD_REF: CAL0081430 heterozygous diploid, classical genetics null Not recorded viable C. albicans orf19.505 ORF SRV2 CAL0000048 PMID: 11325951|CGD_REF: CAL0081430 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.505 ORF SRV2 CAL0000048 PMID: 19943905|CGD_REF: CAL0124661 homozygous diploid, classical genetics null BWP17 hyphal growth: absent liquid GMM plus serum, Lee's medium pH 8.0, or RPMI1640 medium several domain deletion mutants with hyphal growth defects also analyzed C. albicans orf19.505 ORF SRV2 CAL0000048 PMID: 11325951|CGD_REF: CAL0081430 homozygous diploid, classical genetics null Not recorded filamentous growth: absent solid media C. albicans orf19.505 ORF SRV2 CAL0000048 PMID: 11325951|CGD_REF: CAL0081430 heterozygous diploid, classical genetics null Not recorded filamentous growth: normal C. albicans orf19.505 ORF SRV2 CAL0000048 PMID: 14506030|CGD_REF: CAL0080817 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased terbinafine C. albicans orf19.505 ORF SRV2 CAL0000048 PMID: 14506030|CGD_REF: CAL0080817 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased fluconazole C. albicans orf19.505 ORF SRV2 CAL0000048 PMID: 11325951|CGD_REF: CAL0081430 homozygous diploid, classical genetics null Not recorded virulence: absent mouse intravenous infection C. albicans orf19.505 ORF SRV2 CAL0000048 PMID: 11325951|CGD_REF: CAL0081430 heterozygous diploid, classical genetics null Not recorded virulence: decreased mouse intravenous infection C. albicans orf19.505 ORF SRV2 CAL0000048 PMID: 14617167|CGD_REF: CAL0080818 homozygous diploid, classical genetics null Not recorded virulence: decreased mouse intravenous infection C. albicans orf19.5050 ORF MTO1 CAL0001681 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.5053 ORF CAL0001684 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.5056 ORF CAL0001686 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 invasive growth: decreased solid SLAD media C. albicans orf19.5058 ORF SMI1 CAL0001688 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.5058 ORF SMI1 CAL0001688 PMID: 21666076|CGD_REF: CAL0000142107 homozygous diploid, classical genetics null smi1::CdHIS1/smi1::CmLEU2 SN152 biofilm formation: abnormal biofilm cell wall architecture abnormal C. albicans orf19.5058 ORF SMI1 CAL0001688 PMID: 21666076|CGD_REF: CAL0000142107 homozygous diploid, classical genetics null smi1::CdHIS1/smi1::CmLEU2 SN152 viable C. albicans orf19.5058 ORF SMI1 CAL0001688 PMID: 21666076|CGD_REF: CAL0000142107 homozygous diploid, classical genetics null smi1::CdHIS1/smi1::CmLEU2 SN152 resistance to chemicals: decreased amphotericin B|anidulafungin|fluconazole the mutant biofilm exhibited increased susceptibly to fluconazole, anidulafungin and amphotericin B C. albicans orf19.5058 ORF SMI1 CAL0001688 PMID: 21666076|CGD_REF: CAL0000142107 homozygous diploid, classical genetics null smi1::CdHIS1/smi1::CmLEU2 SN152 resistance to chemicals: decreased Calcofluor White C. albicans orf19.5058 ORF SMI1 CAL0001688 PMID: 21666076|CGD_REF: CAL0000142107 heterozygous diploid, classical genetics null smi1::CdHIS1/SMI1 SN152 chemical compound accumulation: decreased (1->3)-beta-D-glucan C. albicans orf19.5058 ORF SMI1 CAL0001688 PMID: 21666076|CGD_REF: CAL0000142107 homozygous diploid, classical genetics null smi1::CdHIS1/smi1::CmLEU2 SN152 chemical compound accumulation: decreased (1->3)-beta-D-glucan|(1->6)-beta-D-glucan 40% decrease in cell wall beta-1,3 glucan - the decrease in cell wall beta-1,3 glucan is consistent with the transmission electron microscopy images demonstrating a thinner electron lucent cell wall layer C. albicans orf19.5058 ORF SMI1 CAL0001688 PMID: 21666076|CGD_REF: CAL0000142107 homozygous diploid, classical genetics null smi1::CdHIS1/smi1::CmLEU2 SN152 RNA accumulation: decreased transcript abundance of GSC1/FKS1 was decreased by nearly 50% in the smi1/smi1 mutant biofilm GSC1 mRNA C. albicans orf19.5058 ORF SMI1 CAL0001688 PMID: 21666076|CGD_REF: CAL0000142107 homozygous diploid, classical genetics null smi1::CdHIS1/smi1::CmLEU2 SN152 virulence: normal immunosuppressed mouse intravenous infection (disseminated murine neutropenic model treated with fluconazole) C. albicans orf19.5058 ORF SMI1 CAL0001688 PMID: 21666076|CGD_REF: CAL0000142107 homozygous diploid, classical genetics null smi1::CdHIS1/smi1::CmLEU2 SN152 hyphal growth: normal C. albicans orf19.5059 ORF GCS1 CAL0001690 PMID: 14706824|CGD_REF: CAL0081348 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.5059 ORF GCS1 CAL0001690 PMID: 14706824|CGD_REF: CAL0081348 homozygous diploid, classical genetics null Not recorded auxotrophy glutathione C. albicans orf19.5059 ORF GCS1 CAL0001690 PMID: 20966090|CGD_REF: CAL0137813 homozygous diploid, classical genetics null SC5314 viable C. albicans orf19.5059 ORF GCS1 CAL0001690 PMID: 20966090|CGD_REF: CAL0137813 homozygous diploid, classical genetics null SC5314 auxotrophy glutathione C. albicans orf19.5059 ORF GCS1 CAL0001690 PMID: 20966090|CGD_REF: CAL0137813 homozygous diploid, classical genetics null SC5314 resistance to killing by host cells: decreased exhibits reduced survival in the presence of macrophages C. albicans orf19.5059 ORF GCS1 CAL0001690 PMID: 20966090|CGD_REF: CAL0137813 homozygous diploid, classical genetics null SC5314 virulence: absent BALB/c mice mouse intravenous infection C. albicans orf19.5059 ORF GCS1 CAL0001690 PMID: 20966090|CGD_REF: CAL0137813 homozygous diploid, classical genetics null SC5314 virulence: decreased THP1 macrophage culture decreased ability to lyse and kill macrophages ex vivo model of infection C. albicans orf19.506 ORF YDJ1 CAL0000049 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.5061 ORF ADE5,7 CAL0001714 PMID: 17600079|CGD_REF: CAL0118017 homozygous diploid, classical genetics null Not recorded metal resistance: decreased silver(1+) C. albicans orf19.5061 ORF ADE5,7 CAL0001714 PMID: 17600079|CGD_REF: CAL0118017 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.5061 ORF ADE5,7 CAL0001714 PMID: 17600079|CGD_REF: CAL0118017 homozygous diploid, classical genetics null BWP17 hyphal growth: decreased low-temperature embedded conditions C. albicans orf19.5061 ORF ADE5,7 CAL0001714 PMID: 17600079|CGD_REF: CAL0118017 homozygous diploid, classical genetics null Not recorded auxotrophy adenine C. albicans orf19.5061 ORF ADE5,7 CAL0001714 PMID: 17600079|CGD_REF: CAL0118017 homozygous diploid, classical genetics null Not recorded metal resistance: decreased copper(2+) C. albicans orf19.5061 ORF ADE5,7 CAL0001714 PMID: 17600079|CGD_REF: CAL0118017 homozygous diploid, classical genetics null Not recorded virulence: decreased mouse intravenous infection C. albicans orf19.5063 ORF COI1 CAL0001718 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient YNB medium C. albicans orf19.5064 ORF MRPL3 CAL0001720 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.5066 ORF CAL0001723 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.5066 ORF CAL0001723 PMID: 16607011|CGD_REF: CAL0115846 heterozygous diploid, classical genetics null SC5314 viable C. albicans orf19.5066 ORF CAL0001723 PMID: 16607011|CGD_REF: CAL0115846 homozygous diploid, classical genetics null SC5314 inviable homozygous null mutant strain could not be recovered, suggesting that the gene is essential under the selection conditions C. albicans orf19.5066 ORF CAL0001723 PMID: 16607011|CGD_REF: CAL0115846 heterozygous diploid, classical genetics repressible SC5314 inviable C. albicans orf19.5068 ORF IRE1 CAL0001725 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.5068 ORF IRE1 CAL0001725 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: increased growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.5068 ORF IRE1 CAL0001725 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: abnormal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.5068 ORF IRE1 CAL0001725 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, classical genetics null SN152 germ tube formation: decreased serum-containing medium C. albicans orf19.5068 ORF IRE1 CAL0001725 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.5068 ORF IRE1 CAL0001725 PMID: 20140194|CGD_REF: CAL0124995 homozygous diploid, classical genetics null Other C. albicans resistance to chemicals: decreased caspofungin C. albicans orf19.5068 ORF IRE1 CAL0001725 PMID: 20140194|CGD_REF: CAL0124995 homozygous diploid, classical genetics null Other C. albicans viable caspofungin C. albicans orf19.5068 ORF IRE1 CAL0001725 PMID: 20140194|CGD_REF: CAL0124995 homozygous diploid, classical genetics null Other C. albicans viable C. albicans orf19.5068 ORF IRE1 CAL0001725 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.5071 ORF NRP1 CAL0001753 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.5073 ORF DPM1 CAL0001756 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.5074 ORF UBA2 CAL0001757 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.5076 ORF PFY1 CAL0001759 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.5076 ORF PFY1 CAL0001759 PMID: 16607011|CGD_REF: CAL0115846 homozygous diploid, classical genetics null SC5314 viable C. albicans orf19.5076 ORF PFY1 CAL0001759 PMID: 16607011|CGD_REF: CAL0115846 heterozygous diploid, classical genetics repressible SC5314 viable C. albicans orf19.5079 ORF CDR4 CAL0001762 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.5079 ORF CDR4 CAL0001762 PMID: 9767132|CGD_REF: CAL0080907 homozygous diploid, classical genetics null CAI-4 resistance to chemicals: normal fluconazole C. albicans orf19.5079 ORF CDR4 CAL0001762 PMID: 9756759|CGD_REF: CAL0080905 heterozygous diploid, classical genetics overexpression Other C. albicans resistance to chemicals: increased triazoles C. albicans orf19.5079 ORF CDR4 CAL0001762 PMID: 9767132|CGD_REF: CAL0080907 homozygous diploid, classical genetics null CAI-4 viable C. albicans orf19.508 ORF QDR1 CAL0000052 PMID: 21414038|CGD_REF: CAL0141808 homozygous diploid, classical genetics null BWP17 viable C. albicans orf19.508 ORF QDR1 CAL0000052 PMID: 24621232|CGD_REF: CAL0000173797 homozygous diploid, classical genetics null SC5314 biofilm formation: abnormal altered biofilm architecture and thickness C. albicans orf19.5081 ORF FUN12 CAL0001783 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.5083 ORF DRG1 CAL0001785 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.5083 ORF DRG1 CAL0001785 PMID: 17159222|CGD_REF: CAL0117046 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.5083 ORF DRG1 CAL0001785 PMID: 17159222|CGD_REF: CAL0117046 homozygous diploid, classical genetics null CAI-4 invasive growth: decreased embedded in agar C. albicans orf19.5083 ORF DRG1 CAL0001785 PMID: 17159222|CGD_REF: CAL0117046 homozygous diploid, classical genetics null Not recorded virulence: decreased exhibits decreased kidney invasion mouse intravenous infection C. albicans orf19.5085 ORF CAL0001788 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.5087 ORF BUD6 CAL0001789 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.5087 ORF BUD6 CAL0001789 PMID: 15976451|CGD_REF: CAL0114312 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.5087 ORF BUD6 CAL0001789 PMID: 16820761|CGD_REF: CAL0116250 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.5087 ORF BUD6 CAL0001789 PMID: 15976451|CGD_REF: CAL0114312 homozygous diploid, classical genetics null Not recorded protein/peptide distribution: abnormal the Spitzenkorper component Mlc1p is mislocalized to the polarisome Mlc1p C. albicans orf19.5087 ORF BUD6 CAL0001789 PMID: 15976451|CGD_REF: CAL0114312 homozygous diploid, classical genetics null BWP17 hyphal growth: abnormal broad hyphae, polarization defect C. albicans orf19.5089 ORF TERT CAL0001791 PMID: 12477797|CGD_REF: CAL0081268 homozygous diploid, classical genetics null Not recorded telomere length: decreased C. albicans orf19.5089 ORF TERT CAL0001791 PMID: 16714448|CGD_REF: CAL0116045 homozygous diploid, classical genetics null Not recorded telomere length: decreased C. albicans orf19.5089 ORF TERT CAL0001791 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.5089 ORF TERT CAL0001791 PMID: 12477797|CGD_REF: CAL0081268 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.5089 ORF TERT CAL0001791 PMID: 16714448|CGD_REF: CAL0116045 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.5090 ORF CAL0001811 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.5090 ORF CAL0001811 PMID: 23572557|CGD_REF: CAL0000158900 homozygous diploid, classical genetics null BWP17 resistance to chemicals: decreased fluconazole RPMI+MOPS+Histidine medium , 6 hours without shaking at 37 degrees C 24 hr fluconazole treatment in 96 well plates C. albicans orf19.5093 ORF CAL0001815 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.5094 ORF BUL1 CAL0001817 PMID: 14663094|CGD_REF: CAL0080633 homozygous diploid, systematic mutation set (homozygous insertion mutants generated with URA3-ARG4-URA3 (UAU1) cassette) null BWP17 viable C. albicans orf19.5095 ORF CAL0001819 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.5097 ORF CAT8 CAL0001821 PMID: 19700635|CGD_REF: CAL0124154 homozygous diploid, classical genetics null Not recorded utilization of carbon source: normal extra-virgin olive oil C. albicans orf19.5097 ORF CAT8 CAL0001821 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.5097 ORF CAT8 CAL0001821 PMID: 15764370|CGD_REF: CAL0082247 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.5097 ORF CAT8 CAL0001821 PMID: 19700635|CGD_REF: CAL0124154 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.5097 ORF CAT8 CAL0001821 PMID: 19700635|CGD_REF: CAL0124154 homozygous diploid, classical genetics null Not recorded utilization of carbon source: normal acetic acid C. albicans orf19.5097 ORF CAT8 CAL0001821 PMID: 19700635|CGD_REF: CAL0124154 homozygous diploid, classical genetics null Not recorded utilization of carbon source: normal oleic acid C. albicans orf19.5097 ORF CAT8 CAL0001821 PMID: 19700635|CGD_REF: CAL0124154 homozygous diploid, classical genetics null Not recorded utilization of carbon source: normal ethanol C. albicans orf19.5097 ORF CAT8 CAL0001821 PMID: 19700635|CGD_REF: CAL0124154 homozygous diploid, classical genetics null Not recorded utilization of carbon source: normal linoleic acid C. albicans orf19.5097 ORF CAT8 CAL0001821 PMID: 19700635|CGD_REF: CAL0124154 homozygous diploid, classical genetics null Not recorded utilization of carbon source: normal glycerol C. albicans orf19.5097 ORF CAT8 CAL0001821 PMID: 22073120|CGD_REF: CAL0000143592 homozygous diploid, classical genetics null BWP17 viable C. albicans orf19.5097 ORF CAT8 CAL0001821 PMID: 22073120|CGD_REF: CAL0000143592 homozygous diploid, classical genetics null BWP17 invasive growth: increased increased agar invasion C. albicans orf19.5097 ORF CAT8 CAL0001821 PMID: 22073120|CGD_REF: CAL0000143592 homozygous diploid, classical genetics null BWP17 viable C. albicans orf19.5097 ORF CAT8 CAL0001821 PMID: 22073120|CGD_REF: CAL0000143592 homozygous diploid, classical genetics null BWP17 colony appearance: abnormal increased colony wrinkling C. albicans orf19.5097 ORF CAT8 CAL0001821 PMID: 22073120|CGD_REF: CAL0000143592 homozygous diploid, classical genetics null BWP17 viable C. albicans orf19.5097 ORF CAT8 CAL0001821 PMID: 22073120|CGD_REF: CAL0000143592 homozygous diploid, classical genetics null BWP17 hyphal growth: increased C. albicans orf19.5097 ORF CAT8 CAL0001821 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 invasive growth: decreased solid SLAD media C. albicans orf19.5098 ORF NTG1 CAL0001822 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.5098 ORF NTG1 CAL0001822 PMID: 18667577|CGD_REF: CAL0119361 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.51 ORF CAL0000601 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.5100 ORF MLT1 CAL0002485 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.5100 ORF MLT1 CAL0002485 PMID: 14663094|CGD_REF: CAL0080633 homozygous diploid, systematic mutation set (homozygous insertion mutants generated with URA3-ARG4-URA3 (UAU1) cassette) null BWP17 viable C. albicans orf19.5100 ORF MLT1 CAL0002485 PMID: 12773383|CGD_REF: CAL0087974 heterozygous diploid, classical genetics (haploinsufficient phenotype assay) unspecified CAI-4 filamentous growth: increased solid YEPD plus serum transposon insertion proximal to, but not within, the ORF C. albicans orf19.5100 ORF MLT1 CAL0002485 PMID: 11929516|CGD_REF: CAL0081541 heterozygous diploid, classical genetics null CAI-4 viable C. albicans orf19.5100 ORF MLT1 CAL0002485 PMID: 11929516|CGD_REF: CAL0081541 homozygous diploid, classical genetics null CAI-4 viable C. albicans orf19.5100 ORF MLT1 CAL0002485 PMID: 11929516|CGD_REF: CAL0081541 heterozygous diploid, classical genetics null CAI-4 viable C. albicans orf19.5100 ORF MLT1 CAL0002485 PMID: 11929516|CGD_REF: CAL0081541 homozygous diploid, classical genetics null Not recorded virulence: decreased decreased host liver cell damage, measured as alanine aminotransferase released after hyphal invasion mouse peritoneal infection C. albicans orf19.5101 ORF CCR4 CAL0002486 PMID: 12773383|CGD_REF: CAL0087974 heterozygous diploid, classical genetics (haploinsufficient phenotype assay) null CAI-4 viable heterozygous transposon insertion C. albicans orf19.5101 ORF CCR4 CAL0002486 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.5101 ORF CCR4 CAL0002486 PMID: 12773383|CGD_REF: CAL0087974 heterozygous diploid, classical genetics (haploinsufficient phenotype assay) null CAI-4 filamentous growth: increased solid Spider medium or solid YEPD plus serum heterozygous transposon insertion C. albicans orf19.5101 ORF CCR4 CAL0002486 PMID: 21299651|CGD_REF: CAL0141610 homozygous diploid, classical genetics null ccr4::ARG4/ccr4::URA3 BWP17 viable C. albicans orf19.5101 ORF CCR4 CAL0002486 PMID: 21299651|CGD_REF: CAL0141610 homozygous diploid, classical genetics null ccr4::ARG4/ccr4::URA3 BWP17 resistance to chemicals: decreased Congo Red C. albicans orf19.5101 ORF CCR4 CAL0002486 PMID: 21299651|CGD_REF: CAL0141610 homozygous diploid, classical genetics null ccr4::ARG4/ccr4::URA3 BWP17 resistance to chemicals: decreased Calcofluor White C. albicans orf19.5101 ORF CCR4 CAL0002486 PMID: 21299651|CGD_REF: CAL0141610 homozygous diploid, classical genetics null ccr4::ARG4/ccr4::URA3 BWP17 resistance to chemicals: decreased caspofungin C. albicans orf19.5101 ORF CCR4 CAL0002486 PMID: 21299651|CGD_REF: CAL0141610 homozygous diploid, classical genetics null ccr4::ARG4/ccr4::URA3 BWP17 filamentous growth: decreased YPD medium with 10% serum or Spider medium C. albicans orf19.5101 ORF CCR4 CAL0002486 PMID: 21299651|CGD_REF: CAL0141610 homozygous diploid, classical genetics null ccr4::ARG4/ccr4::URA3 BWP17 virulence: decreased mouse intravenous infection C. albicans orf19.5101 ORF CCR4 CAL0002486 PMID: 21299651|CGD_REF: CAL0141610 homozygous diploid, classical genetics null ccr4::ARG4/ccr4::URA3 BWP17 mitochondrial morphology: abnormal C. albicans orf19.5102 ORF PLB5 CAL0002487 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.5102 ORF PLB5 CAL0002487 PMID: 16759910|CGD_REF: CAL0116674 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.5102 ORF PLB5 CAL0002487 PMID: 16759910|CGD_REF: CAL0116674 homozygous diploid, classical genetics null Not recorded virulence: decreased exhibits decreased organ colonization mouse intravenous infection C. albicans orf19.5103 ORF CAL0002488 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.5104 ORF LTP1 CAL0002489 PMID: 18708562|CGD_REF: CAL0119375 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.5104 ORF LTP1 CAL0002489 PMID: 18708562|CGD_REF: CAL0119375 homozygous diploid, classical genetics null Not recorded virulence: normal silkworm insect infection C. albicans orf19.5104 ORF LTP1 CAL0002489 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 invasive growth: decreased solid SLAD media C. albicans orf19.5105 ORF MED15 CAL0002490 PMID: 23873866|CGD_REF: CAL0000172574 homozygous diploid, classical genetics null SN152 phenotypic switching: abnormal C. albicans orf19.5106 ORF DIP2 CAL0002491 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.5106 ORF DIP2 CAL0002491 PMID: 12773383|CGD_REF: CAL0087974 heterozygous diploid, classical genetics (haploinsufficient phenotype assay) unspecified CAI-4 filamentous growth: increased solid Spider medium transposon insertion proximal to, but not within, the ORF C. albicans orf19.5106 ORF DIP2 CAL0002491 PMID: 19623926|CGD_REF: CAL0124054 heterozygous diploid, competitive growth (haploinsufficient phenotype assay, barcode deletion set) null SC5314 resistance to chemicals: increased parnafungin C. albicans orf19.5106 ORF DIP2 CAL0002491 PMID: 12773383|CGD_REF: CAL0087974 heterozygous diploid, classical genetics (haploinsufficient phenotype assay) unspecified CAI-4 colony size: decreased solid Spider medium transposon insertion proximal to, but not within, the ORF C. albicans orf19.5107 ORF NOT5 CAL0002492 PMID: 12787355|CGD_REF: CAL0080855 homozygous diploid, classical genetics null Not recorded resistance to chemicals: normal Calcofluor White C. albicans orf19.5107 ORF NOT5 CAL0002492 PMID: 12787355|CGD_REF: CAL0080855 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased sodium dodecyl sulfate C. albicans orf19.5107 ORF NOT5 CAL0002492 PMID: 12787355|CGD_REF: CAL0080855 homozygous diploid, classical genetics null Not recorded heat sensitivity: normal reintegrant C. albicans orf19.5107 ORF NOT5 CAL0002492 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.5107 ORF NOT5 CAL0002492 PMID: 12787355|CGD_REF: CAL0080855 heterozygous diploid, classical genetics null Not recorded viable YPD liquid, 37 deg C wild-type growth rate C. albicans orf19.5107 ORF NOT5 CAL0002492 PMID: 12787355|CGD_REF: CAL0080855 homozygous diploid, classical genetics null Not recorded viable liquid YPD at 37 deg C C. albicans orf19.5107 ORF NOT5 CAL0002492 PMID: 14500538|CGD_REF: CAL0081606 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.5107 ORF NOT5 CAL0002492 PMID: 12787355|CGD_REF: CAL0080855 homozygous diploid, classical genetics null Not recorded adhesion: decreased adhesion to human buccal epithelial cells C. albicans orf19.5107 ORF NOT5 CAL0002492 PMID: 14500538|CGD_REF: CAL0081606 homozygous diploid, classical genetics null Not recorded adhesion: decreased adhesion to human buccal epithelial cells C. albicans orf19.5107 ORF NOT5 CAL0002492 PMID: 12787355|CGD_REF: CAL0080855 homozygous diploid, classical genetics null SC5314 hyphal growth: absent liquid RPMI 1640 or YPD plus serum C. albicans orf19.5107 ORF NOT5 CAL0002492 PMID: 12787355|CGD_REF: CAL0080855 heterozygous diploid, classical genetics null SC5314 hyphal growth: decreased liquid RPMI 1640 or YPD plus serum C. albicans orf19.5107 ORF NOT5 CAL0002492 PMID: 12787355|CGD_REF: CAL0080855 homozygous diploid, classical genetics null SC5314 hyphal growth: absent solid YEPD plus serum, M199, Spider, or Lee's media C. albicans orf19.5107 ORF NOT5 CAL0002492 PMID: 12787355|CGD_REF: CAL0080855 heterozygous diploid, classical genetics null SC5314 hyphal growth: normal solid YEPD plus serum, M199, Spider, or Lee's media C. albicans orf19.5107 ORF NOT5 CAL0002492 PMID: 14500538|CGD_REF: CAL0081606 homozygous diploid, classical genetics null CAI-4 hyphal growth: absent solid M199 or Spider media C. albicans orf19.5107 ORF NOT5 CAL0002492 PMID: 12787355|CGD_REF: CAL0080855 homozygous diploid, classical genetics null Not recorded resistance to chemicals: normal caffeine C. albicans orf19.5107 ORF NOT5 CAL0002492 PMID: 12787355|CGD_REF: CAL0080855 homozygous diploid, classical genetics null Not recorded virulence: decreased mouse intravenous infection C. albicans orf19.5107 ORF NOT5 CAL0002492 PMID: 14500538|CGD_REF: CAL0081606 heterozygous diploid, classical genetics null Not recorded virulence: normal mouse intravenous infection C. albicans orf19.5107 ORF NOT5 CAL0002492 PMID: 14500538|CGD_REF: CAL0081606 homozygous diploid, classical genetics null Not recorded virulence: decreased C. albicans orf19.511 ORF CAL0000077 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.5110 ORF OPY2 CAL0002507 PMID: 23149115|CGD_REF: CAL0000158110 homozygous diploid, classical genetics null CAF2-1 viable C. albicans orf19.5110 ORF OPY2 CAL0002507 PMID: 23149115|CGD_REF: CAL0000158110 homozygous diploid, classical genetics null CAF2-1 resistance to chemicals: decreased Congo Red C. albicans orf19.5112 ORF TKL1 CAL0002508 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.5114 ORF CAL0002510 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.5117 ORF OLE1 CAL0002511 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.5117 ORF OLE1 CAL0002511 PMID: 15184585|CGD_REF: CAL0081531 heterozygous diploid, classical genetics repressible CAI-4 hyphal growth: absent solid Spider or Lee's media C. albicans orf19.5117 ORF OLE1 CAL0002511 PMID: 15184585|CGD_REF: CAL0081531 heterozygous diploid, classical genetics repressible Not recorded chlamydospore formation: absent C. albicans orf19.5117 ORF OLE1 CAL0002511 PMID: 15184585|CGD_REF: CAL0081531 homozygous diploid, classical genetics null Not recorded inviable C. albicans orf19.5117 ORF OLE1 CAL0002511 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 invasive growth: decreased solid SLAD media C. albicans orf19.5117 ORF OLE1 CAL0002511 PMID: 21135205|CGD_REF: CAL0139967 heterozygous diploid, large-scale survey (large-scale identification of genes essential for virulence in mouse) repressible CAI-4 virulence: absent mouse intravenous infection C. albicans orf19.512 ORF CAL0000078 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.512 ORF CAL0000078 PMID: 16607011|CGD_REF: CAL0115846 heterozygous diploid, classical genetics null SC5314 viable C. albicans orf19.512 ORF CAL0000078 PMID: 16607011|CGD_REF: CAL0115846 homozygous diploid, classical genetics null SC5314 inviable homozygous null mutant strain could not be recovered, suggesting that the gene is essential under the selection conditions C. albicans orf19.512 ORF CAL0000078 PMID: 16607011|CGD_REF: CAL0115846 heterozygous diploid, classical genetics repressible SC5314 inviable C. albicans orf19.5121 ORF OPT5 CAL0002526 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.5129 ORF CAL0002534 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.5129 ORF CAL0002534 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.5129 ORF CAL0002534 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.5129 ORF CAL0002534 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.5129 ORF CAL0002534 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.5131 ORF CAL0002548 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.5133 ORF ZCF29 CAL0002550 PMID: 20041210|CGD_REF: CAL0124764 homozygous diploid, systematic mutation set null SN152 resistance to chemicals: increased fenpropimorph strongly resistant C. albicans orf19.5133 ORF ZCF29 CAL0002550 PMID: 20041210|CGD_REF: CAL0124764 homozygous diploid, systematic mutation set null SN152 resistance to chemicals: decreased rapamycin strongly sensitive C. albicans orf19.5133 ORF ZCF29 CAL0002550 PMID: 20041210|CGD_REF: CAL0124764 homozygous diploid, systematic mutation set null SN152 resistance to chemicals: decreased caffeine severely sensitive C. albicans orf19.5133 ORF ZCF29 CAL0002550 PMID: 20041210|CGD_REF: CAL0124764 homozygous diploid, systematic mutation set null SN152 oxidative stress resistance: decreased menadione strongly sensitive C. albicans orf19.5133 ORF ZCF29 CAL0002550 PMID: 22073120|CGD_REF: CAL0000143592 homozygous diploid, classical genetics null BWP17 viable C. albicans orf19.5133 ORF ZCF29 CAL0002550 PMID: 22073120|CGD_REF: CAL0000143592 homozygous diploid, classical genetics null BWP17 colony appearance: abnormal decreased colony wrinkling C. albicans orf19.5133 ORF ZCF29 CAL0002550 PMID: 22073120|CGD_REF: CAL0000143592 homozygous diploid, classical genetics null BWP17 hyphal growth: decreased C. albicans orf19.5137.1 ORF HHO1 CAF0007031 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient SLAD medium C. albicans orf19.5138 ORF IFA21 CAL0002555 PMID: 14663094|CGD_REF: CAL0080633 homozygous diploid, systematic mutation set (homozygous insertion mutants generated with URA3-ARG4-URA3 (UAU1) cassette) null BWP17 viable C. albicans orf19.5138 ORF IFA21 CAL0002555 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.5138 ORF IFA21 CAL0002555 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.5138 ORF IFA21 CAL0002555 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.5138 ORF IFA21 CAL0002555 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.514 ORF SNP3 CAL0000080 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.5140 ORF CAL0002573 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.5140 ORF CAL0002573 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.5140 ORF CAL0002573 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.5140 ORF CAL0002573 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.5141 ORF CAL0002574 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.5141 ORF CAL0002574 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.5141 ORF CAL0002574 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.5141 ORF CAL0002574 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.5142 ORF DFR1 CAL0002575 PMID: 3031460|CGD_REF: CAL0080671 unknown ploidy, classical genetics overexpression Other C. albicans protein activity: increased dihydrofolate reductase C. albicans orf19.5143 ORF TIM54 CAL0002576 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.5147 ORF LMO1 CAL0002579 PMID: 20444104|CGD_REF: CAL0125731 homozygous diploid, classical genetics null lmo1-2::HIS1/lmo1-2::URA3 BWP17 viable C. albicans orf19.5147 ORF LMO1 CAL0002579 PMID: 20444104|CGD_REF: CAL0125731 homozygous diploid, classical genetics null lmo1-2::HIS1/lmo1-2::URA3 BWP17 invasive growth: absent embedded in an agar matrix C. albicans orf19.5147 ORF LMO1 CAL0002579 PMID: 20444104|CGD_REF: CAL0125731 homozygous diploid, classical genetics null lmo1-2::HIS1/lmo1-2::URA3 BWP17 filamentous growth: decreased Spider solid media C. albicans orf19.5147 ORF LMO1 CAL0002579 PMID: 20444104|CGD_REF: CAL0125731 homozygous diploid, classical genetics null lmo1-2::HIS1/lmo1-2::URA3 BWP17 resistance to chemicals: decreased Congo Red C. albicans orf19.5147 ORF LMO1 CAL0002579 PMID: 20444104|CGD_REF: CAL0125731 homozygous diploid, classical genetics null lmo1-2::HIS1/lmo1-2::URA3 BWP17 resistance to chemicals: decreased Calcofluor White C. albicans orf19.5148 ORF CYR1 CAL0002580 PMID: 15269278|CGD_REF: CAL0082117 homozygous diploid, classical genetics null Not recorded flocculation: increased C. albicans orf19.5148 ORF CYR1 CAL0002580 PMID: 15269278|CGD_REF: CAL0082117 homozygous diploid, classical genetics null Not recorded resistance to enzymatic treatment: increased zymolyase C. albicans orf19.5148 ORF CYR1 CAL0002580 PMID: 15269278|CGD_REF: CAL0082117 homozygous diploid, classical genetics null Not recorded thermotolerance: increased slightly increased resistance to heat shock C. albicans orf19.5148 ORF CYR1 CAL0002580 PMID: 15269278|CGD_REF: CAL0082117 homozygous diploid, classical genetics null Not recorded resistance to chemicals: increased Calcofluor White C. albicans orf19.5148 ORF CYR1 CAL0002580 PMID: 14506030|CGD_REF: CAL0080817 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased fenpropimorph drug sensitivity of the mutant is enhanced by MDL-12330A and partially rescued by cAMP C. albicans orf19.5148 ORF CYR1 CAL0002580 PMID: 14506030|CGD_REF: CAL0080817 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased itraconazole drug sensitivity of the mutant is enhanced by MDL-12330A and partially rescued by cAMP C. albicans orf19.5148 ORF CYR1 CAL0002580 PMID: 14506030|CGD_REF: CAL0080817 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased miconazole drug sensitivity of the mutant is enhanced by MDL-12330A and partially rescued by cAMP C. albicans orf19.5148 ORF CYR1 CAL0002580 PMID: 14506030|CGD_REF: CAL0080817 homozygous diploid, classical genetics null Not recorded vegetative growth: decreased rate growth defect is rescued by cAMP C. albicans orf19.5148 ORF CYR1 CAL0002580 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.5148 ORF CYR1 CAL0002580 PMID: 14507372|CGD_REF: CAL0088818 heterozygous diploid, large-scale survey (large-scale identification of essential genes by gene replacement and conditional expression (GRACE) method) repressible CAI-4 viable one allele is deleted and the other is placed under repressible Tet promoter C. albicans orf19.5148 ORF CYR1 CAL0002580 PMID: 16407097|CGD_REF: CAL0115390 homozygous diploid, classical genetics null Not recorded apoptosis: decreased increased resistance to apoptosis-inducing stimuli C. albicans orf19.5148 ORF CYR1 CAL0002580 PMID: 16856944|CGD_REF: CAL0116319 heterozygous diploid, classical genetics reduction of function cyr1-K388A (mutation of the RA domain) CAI-4 germ tube formation: absent C. albicans orf19.5148 ORF CYR1 CAL0002580 PMID: 16856944|CGD_REF: CAL0116319 heterozygous diploid, classical genetics reduction of function cyr1-L349A (mutation of the RA domain) CAI-4 germ tube formation: absent C. albicans orf19.5148 ORF CYR1 CAL0002580 PMID: 15269278|CGD_REF: CAL0082117 homozygous diploid, classical genetics null Not recorded osmotic stress resistance: decreased C. albicans orf19.5148 ORF CYR1 CAL0002580 PMID: 11694594|CGD_REF: CAL0080865 homozygous diploid, classical genetics null Not recorded chemical compound accumulation: decreased 3',5'-cyclic AMP C. albicans orf19.5148 ORF CYR1 CAL0002580 PMID: 14506030|CGD_REF: CAL0080817 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased amphotericin B drug sensitivity of the mutant is enhanced by MDL-12330A and partially rescued by cAMP C. albicans orf19.5148 ORF CYR1 CAL0002580 PMID: 19200725|CGD_REF: CAL0122386 homozygous diploid, classical genetics null Not recorded phenotypic switching: decreased air or 1% CO2 white-to-opaque switching C. albicans orf19.5148 ORF CYR1 CAL0002580 PMID: 16267276|CGD_REF: CAL0115298 homozygous diploid, classical genetics null CAI-4 filamentous growth: increased embedded in YPS agar, 25 deg C exhibits microaerophilic growth C. albicans orf19.5148 ORF CYR1 CAL0002580 PMID: 14506030|CGD_REF: CAL0080817 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased terbinafine drug sensitivity of the mutant is enhanced by MDL-12330A and partially rescued by cAMP C. albicans orf19.5148 ORF CYR1 CAL0002580 PMID: 14506030|CGD_REF: CAL0080817 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased fluconazole C. albicans orf19.5148 ORF CYR1 CAL0002580 PMID: 12379711|CGD_REF: CAL0081037 homozygous diploid, classical genetics null CAI-4 resistance to killing by host cells: decreased in vitro model of infection (RAW264.7 macrophages) C. albicans orf19.5148 ORF CYR1 CAL0002580 PMID: 12379711|CGD_REF: CAL0081037 homozygous diploid, classical genetics null CAF2-1 resistance to killing by host cells: decreased in vitro model of infection (RAW264.7 macrophages) C. albicans orf19.5148 ORF CYR1 CAL0002580 PMID: 21992526|CGD_REF: CAL0000143470 homozygous diploid, classical genetics null CYR1-E1541K BWP17 filamentous growth: increased E1541K mutation causeS constitutive filamentous growth C. albicans orf19.5148 ORF CYR1 CAL0002580 PMID: 21992526|CGD_REF: CAL0000143470 homozygous diploid, classical genetics null CYR1-E1541K BWP17 resistance to chemicals: decreased farnesol C. albicans orf19.5148 ORF CYR1 CAL0002580 PMID: 21992526|CGD_REF: CAL0000143470 homozygous diploid, classical genetics unspecified CYR1-E1541K BWP17 resistance to chemicals: increased farnesol C. albicans orf19.5148 ORF CYR1 CAL0002580 PMID: 21992526|CGD_REF: CAL0000143470 homozygous diploid, classical genetics unspecified CYR1-E1541K BWP17 chemical compound accumulation: increased riboflavin C. albicans orf19.5148 ORF CYR1 CAL0002580 PMID: 22923045|CGD_REF: CAL0000157829 homozygous diploid, competitive growth null Other C. albicans formation of anatomical structure: absent elevated concentrations of CO2 at 37 deg finger structure C. albicans orf19.5148 ORF CYR1 CAL0002580 PMID: 12381467|CGD_REF: CAL0087147 homozygous diploid, classical genetics null Not recorded virulence: decreased insect infection C. albicans orf19.5148 ORF CYR1 CAL0002580 PMID: 11694594|CGD_REF: CAL0080865 homozygous diploid, classical genetics null Not recorded virulence: absent mouse intravenous infection C. albicans orf19.5148 ORF CYR1 CAL0002580 PMID: 11694594|CGD_REF: CAL0080865 homozygous diploid, classical genetics null Not recorded virulence: absent mouse oropharyngeal infection C. albicans orf19.5148 ORF CYR1 CAL0002580 PMID: 20118211|CGD_REF: CAL0125028 homozygous diploid, classical genetics null CAI-4 oxidative stress resistance: decreased decreased H2O2 resistance C. albicans orf19.5148 ORF CYR1 CAL0002580 PMID: 20118211|CGD_REF: CAL0125028 homozygous diploid, classical genetics null CAI-4 oxidative stress resistance: decreased decreased H2O2 resistance C. albicans orf19.5148 ORF CYR1 CAL0002580 PMID: 21124988|CGD_REF: CAL0139960 aneuploid, classical genetics reduction of function CYR1/CYR1/pTEF2-CYR1(K1373A) CAI-4 virulence: decreased survival assessed over 48 hours endpoint survival was similar to wild-type; mutants were slightly delayed in killing insect infection (Toll-deficient D. melanogaster) C. albicans orf19.5148 ORF CYR1 CAL0002580 PMID: 21124988|CGD_REF: CAL0139960 aneuploid, classical genetics reduction of function CYR1/CYR1/pTEF2-CYR1(K1373A) CAI-4 virulence: normal mouse intravenous infection C. albicans orf19.5148 ORF CYR1 CAL0002580 PMID: 11694594|CGD_REF: CAL0080865 homozygous diploid, classical genetics null CAI-4 resistance to killing by host cells: decreased in vitro model of infection (RAW264.7 clone D3 murine macrophages) C. albicans orf19.5148 ORF CYR1 CAL0002580 PMID: 11694594|CGD_REF: CAL0080865 homozygous diploid, classical genetics null CAI-4 viable C. albicans orf19.5148 ORF CYR1 CAL0002580 PMID: 11694594|CGD_REF: CAL0080865 homozygous diploid, classical genetics null CAI-4 filamentous growth: absent various liquid and solid media C. albicans orf19.5148 ORF CYR1 CAL0002580 PMID: 11694594|CGD_REF: CAL0080865 homozygous diploid, classical genetics null CAI-4 vegetative growth: decreased rate C. albicans orf19.5148 ORF CYR1 CAL0002580 PMID: 11694594|CGD_REF: CAL0080865 homozygous diploid, classical genetics null CAI-4 hyphal growth: absent C. albicans orf19.5148 ORF CYR1 CAL0002580 PMID: 21124988|CGD_REF: CAL0139960 aneuploid, classical genetics reduction of function CYR1/CYR1/pTEF2 CYR1(K1373A) CAI-4 filamentous growth: decreased >5% CO2 specific disruption of CO2-induced filamentation C. albicans orf19.5148 ORF CYR1 CAL0002580 PMID: 11694594|CGD_REF: CAL0080865 homozygous diploid, classical genetics null CAI-4 chemical compound accumulation: decreased 3',5'-cyclic AMP C. albicans orf19.5156 ORF CAL0002593 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.5159 ORF DUG3 CAL0002597 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.516 ORF CAL0000084 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.5162 ORF BCK1 CAL0002621 PMID: 20140194|CGD_REF: CAL0124995 homozygous diploid, classical genetics null Other C. albicans resistance to chemicals: decreased caspofungin C. albicans orf19.5162 ORF BCK1 CAL0002621 PMID: 20140194|CGD_REF: CAL0124995 homozygous diploid, classical genetics null Other C. albicans viable caspofungin C. albicans orf19.5162 ORF BCK1 CAL0002621 PMID: 20865172|CGD_REF: CAL0126252 homozygous diploid, classical genetics null SN95 resistance to chemicals: decreased terbinafine C. albicans orf19.5162 ORF BCK1 CAL0002621 PMID: 20865172|CGD_REF: CAL0126252 homozygous diploid, classical genetics null SN95 resistance to chemicals: decreased fenpropimorph C. albicans orf19.5162 ORF BCK1 CAL0002621 PMID: 20865172|CGD_REF: CAL0126252 homozygous diploid, classical genetics null SN95 resistance to chemicals: decreased fluconazole C. albicans orf19.5162 ORF BCK1 CAL0002621 PMID: 20140194|CGD_REF: CAL0124995 homozygous diploid, classical genetics null Other C. albicans viable C. albicans orf19.5163 ORF SFI1 CAL0002623 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.5163 ORF SFI1 CAL0002623 PMID: 14507372|CGD_REF: CAL0088818 heterozygous diploid, large-scale survey (large-scale identification of essential genes by gene replacement and conditional expression (GRACE) method) repressible CAI-4 inviable one allele is deleted and the other is placed under repressible Tet promoter C. albicans orf19.5164 ORF ECM39 CAL0002625 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.5166 ORF DBF4 CAL0002629 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.5166 ORF DBF4 CAL0002629 PMID: 21135205|CGD_REF: CAL0139967 heterozygous diploid, large-scale survey (large-scale identification of genes essential for virulence in mouse) repressible CAI-4 virulence: absent mouse intravenous infection C. albicans orf19.5168 ORF CAL0002631 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.517 ORF HAP31 CAL0000086 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.517 ORF HAP31 CAL0000086 PMID: 20041210|CGD_REF: CAL0124764 homozygous diploid, systematic mutation set null SN152 resistance to chemicals: increased rapamycin strongly resistant C. albicans orf19.517 ORF HAP31 CAL0000086 PMID: 20041210|CGD_REF: CAL0124764 homozygous diploid, systematic mutation set null SN152 metal resistance: increased copper(2+) strongly resistant C. albicans orf19.5170 ORF ENA21 CAL0002653 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.5170 ORF ENA21 CAL0002653 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.5170 ORF ENA21 CAL0002653 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.5170 ORF ENA21 CAL0002653 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.5171 ORF PMT1 CAL0002654 PMID: 15659169|CGD_REF: CAL0082300 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased ketoconazole C. albicans orf19.5171 ORF PMT1 CAL0002654 PMID: 15659169|CGD_REF: CAL0082300 homozygous diploid, classical genetics null Not recorded flocculation: increased C. albicans orf19.5171 ORF PMT1 CAL0002654 PMID: 15659169|CGD_REF: CAL0082300 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased Calcofluor White C. albicans orf19.5171 ORF PMT1 CAL0002654 PMID: 9694829|CGD_REF: CAL0080732 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased Calcofluor White C. albicans orf19.5171 ORF PMT1 CAL0002654 PMID: 9694829|CGD_REF: CAL0080732 heterozygous diploid, classical genetics null Not recorded resistance to chemicals: normal Calcofluor White C. albicans orf19.5171 ORF PMT1 CAL0002654 PMID: 9694829|CGD_REF: CAL0080732 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased sodium dodecyl sulfate C. albicans orf19.5171 ORF PMT1 CAL0002654 PMID: 9694829|CGD_REF: CAL0080732 heterozygous diploid, classical genetics null Not recorded resistance to chemicals: normal sodium dodecyl sulfate C. albicans orf19.5171 ORF PMT1 CAL0002654 PMID: 15659169|CGD_REF: CAL0082300 homozygous diploid, classical genetics null Not recorded heat sensitivity: increased C. albicans orf19.5171 ORF PMT1 CAL0002654 PMID: 9694829|CGD_REF: CAL0080732 homozygous diploid, classical genetics null Not recorded vegetative growth: decreased rate C. albicans orf19.5171 ORF PMT1 CAL0002654 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.5171 ORF PMT1 CAL0002654 PMID: 9694829|CGD_REF: CAL0080732 heterozygous diploid, classical genetics null Not recorded viable C. albicans orf19.5171 ORF PMT1 CAL0002654 PMID: 9694829|CGD_REF: CAL0080732 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.5171 ORF PMT1 CAL0002654 PMID: 9694829|CGD_REF: CAL0080732 homozygous diploid, classical genetics null Not recorded protein/peptide modification: decreased Als1p is under-glycosylated Als1p C. albicans orf19.5171 ORF PMT1 CAL0002654 PMID: 9694829|CGD_REF: CAL0080732 homozygous diploid, classical genetics null Not recorded protein/peptide modification: abnormal Als1p C. albicans orf19.5171 ORF PMT1 CAL0002654 PMID: 9694829|CGD_REF: CAL0080732 homozygous diploid, classical genetics null Not recorded adhesion: decreased adhesion to human colon carcinoma epithelial cells C. albicans orf19.5171 ORF PMT1 CAL0002654 PMID: 9694829|CGD_REF: CAL0080732 heterozygous diploid, classical genetics null Not recorded adhesion: normal adhesion to human colon carcinoma epithelial cells C. albicans orf19.5171 ORF PMT1 CAL0002654 PMID: 15659169|CGD_REF: CAL0082300 homozygous diploid, classical genetics null CAI-4 hyphal growth: absent Lee's or Spider media C. albicans orf19.5171 ORF PMT1 CAL0002654 PMID: 15659169|CGD_REF: CAL0082300 homozygous diploid, classical genetics null CAI-4 hyphal growth: decreased serum-containing medium C. albicans orf19.5171 ORF PMT1 CAL0002654 PMID: 9694829|CGD_REF: CAL0080732 homozygous diploid, classical genetics null CAI-4 hyphal growth: normal solid media plus serum, liquid media plus serum or GlcNAc C. albicans orf19.5171 ORF PMT1 CAL0002654 PMID: 9694829|CGD_REF: CAL0080732 homozygous diploid, classical genetics null CAI-4 hyphal growth: absent solid Spider medium C. albicans orf19.5171 ORF PMT1 CAL0002654 PMID: 9694829|CGD_REF: CAL0080732 heterozygous diploid, classical genetics null CAI-4 hyphal growth: decreased solid Spider medium C. albicans orf19.5171 ORF PMT1 CAL0002654 PMID: 10672182|CGD_REF: CAL0080733 homozygous diploid, classical genetics null pmt1::hisG-URA3-hisG/pmt1::hisG CAI-4 cell wall morphology: abnormal C. albicans orf19.5171 ORF PMT1 CAL0002654 PMID: 10809683|CGD_REF: CAL0080975 homozygous diploid, classical genetics null pmt1::hisG-URA3-hisG/pmt1::hisG CAI-4 resistance to chemicals: decreased Congo red C. albicans orf19.5171 ORF PMT1 CAL0002654 PMID: 10672182|CGD_REF: CAL0080733 homozygous diploid, classical genetics null pmt1::hisG-URA3-hisG/pmt1::hisG CAI-4 resistance to chemicals: decreased nikkomycin Z C. albicans orf19.5171 ORF PMT1 CAL0002654 PMID: 10672182|CGD_REF: CAL0080733 homozygous diploid, classical genetics null pmt1::hisG-URA3-hisG/pmt1::hisG CAI-4 resistance to enzymatic treatment: decreased exochitinase C. albicans orf19.5171 ORF PMT1 CAL0002654 PMID: 10809683|CGD_REF: CAL0080975 homozygous diploid, classical genetics null pmt1::hisG-URA3-hisG/pmt1::hisG CAI-4 viable C. albicans orf19.5171 ORF PMT1 CAL0002654 PMID: 15659169|CGD_REF: CAL0082300 homozygous diploid, classical genetics null Not recorded cell wall morphology: abnormal drastically altered composition C. albicans orf19.5171 ORF PMT1 CAL0002654 PMID: 9694829|CGD_REF: CAL0080732 homozygous diploid, classical genetics null Not recorded cellular morphology: normal C. albicans orf19.5171 ORF PMT1 CAL0002654 PMID: 9694829|CGD_REF: CAL0080732 heterozygous diploid, classical genetics null Not recorded resistance to chemicals: normal amphotericin B C. albicans orf19.5171 ORF PMT1 CAL0002654 PMID: 9694829|CGD_REF: CAL0080732 homozygous diploid, classical genetics null Not recorded resistance to chemicals: normal amphotericin B C. albicans orf19.5171 ORF PMT1 CAL0002654 PMID: 9694829|CGD_REF: CAL0080732 homozygous diploid, classical genetics null Not recorded cytokinesis: decreased C. albicans orf19.5171 ORF PMT1 CAL0002654 PMID: 9694829|CGD_REF: CAL0080732 homozygous diploid, classical genetics null CAI-4 pseudohyphal growth: normal liquid YP medium, 37 deg C C. albicans orf19.5171 ORF PMT1 CAL0002654 PMID: 9694829|CGD_REF: CAL0080732 heterozygous diploid, classical genetics null Not recorded resistance to chemicals: normal caffeine C. albicans orf19.5171 ORF PMT1 CAL0002654 PMID: 9694829|CGD_REF: CAL0080732 homozygous diploid, classical genetics null Not recorded resistance to chemicals: normal caffeine C. albicans orf19.5171 ORF PMT1 CAL0002654 PMID: 9694829|CGD_REF: CAL0080732 heterozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased Hygromycin B sensitivity is intermediate between that of the homozygous null mutant and wild type C. albicans orf19.5171 ORF PMT1 CAL0002654 PMID: 15659169|CGD_REF: CAL0082300 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased Hygromycin B C. albicans orf19.5171 ORF PMT1 CAL0002654 PMID: 9694829|CGD_REF: CAL0080732 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased Hygromycin B C. albicans orf19.5171 ORF PMT1 CAL0002654 PMID: 9694829|CGD_REF: CAL0080732 heterozygous diploid, classical genetics null Not recorded resistance to chemicals: normal nystatin C. albicans orf19.5171 ORF PMT1 CAL0002654 PMID: 9694829|CGD_REF: CAL0080732 homozygous diploid, classical genetics null Not recorded resistance to chemicals: normal nystatin C. albicans orf19.5171 ORF PMT1 CAL0002654 PMID: 9694829|CGD_REF: CAL0080732 heterozygous diploid, classical genetics null Not recorded resistance to chemicals: normal fluphenazine C. albicans orf19.5171 ORF PMT1 CAL0002654 PMID: 9694829|CGD_REF: CAL0080732 homozygous diploid, classical genetics null Not recorded resistance to chemicals: normal fluphenazine C. albicans orf19.5171 ORF PMT1 CAL0002654 PMID: 9694829|CGD_REF: CAL0080732 heterozygous diploid, classical genetics null Not recorded resistance to chemicals: normal G418 C. albicans orf19.5171 ORF PMT1 CAL0002654 PMID: 15659169|CGD_REF: CAL0082300 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased geneticin C. albicans orf19.5171 ORF PMT1 CAL0002654 PMID: 9694829|CGD_REF: CAL0080732 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased geneticin C. albicans orf19.5171 ORF PMT1 CAL0002654 PMID: 9694829|CGD_REF: CAL0080732 heterozygous diploid, classical genetics null Not recorded resistance to chemicals: normal methotrexate + sulfanilamide C. albicans orf19.5171 ORF PMT1 CAL0002654 PMID: 9694829|CGD_REF: CAL0080732 homozygous diploid, classical genetics null Not recorded resistance to chemicals: normal methotrexate + sulfanilamide C. albicans orf19.5171 ORF PMT1 CAL0002654 PMID: 15659169|CGD_REF: CAL0082300 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased Congo Red C. albicans orf19.5171 ORF PMT1 CAL0002654 PMID: 9694829|CGD_REF: CAL0080732 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased clotrimazole C. albicans orf19.5171 ORF PMT1 CAL0002654 PMID: 9694829|CGD_REF: CAL0080732 heterozygous diploid, classical genetics null Not recorded resistance to chemicals: normal clotrimazole C. albicans orf19.5171 ORF PMT1 CAL0002654 PMID: 9694829|CGD_REF: CAL0080732 heterozygous diploid, classical genetics null Not recorded resistance to chemicals: normal fluconazole C. albicans orf19.5171 ORF PMT1 CAL0002654 PMID: 9694829|CGD_REF: CAL0080732 homozygous diploid, classical genetics null Not recorded resistance to chemicals: normal fluconazole C. albicans orf19.5171 ORF PMT1 CAL0002654 PMID: 21375589|CGD_REF: CAL0141772 homozygous diploid, classical genetics null CAF2-1 resistance to chemicals: decreased tunicamycin C. albicans orf19.5171 ORF PMT1 CAL0002654 PMID: 17005840|CGD_REF: CAL0116746 homozygous diploid, classical genetics null CAF2-1 biofilm formation: decreased significant reduction C. albicans orf19.5171 ORF PMT1 CAL0002654 PMID: 9694829|CGD_REF: CAL0080732 homozygous diploid, classical genetics null Not recorded virulence: absent exhibits no kidney colonization mouse intravenous infection C. albicans orf19.5171 ORF PMT1 CAL0002654 PMID: 9694829|CGD_REF: CAL0080732 heterozygous diploid, classical genetics null Not recorded virulence: decreased wild-type kidney colonization mouse intravenous infection C. albicans orf19.5174 ORF TAF19 CAL0002660 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.5174 ORF TAF19 CAL0002660 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, competitive growth (haploinsufficient phenotype assay, barcode deletion set) null SC5314 resistance to chemicals: decreased amphotericin B C. albicans orf19.5175 ORF CAL0002662 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.5178 ORF ERG5 CAL0002665 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.5178 ORF ERG5 CAL0002665 PMID: 12773383|CGD_REF: CAL0087974 heterozygous diploid, classical genetics (haploinsufficient phenotype assay) unspecified CAI-4 filamentous growth: increased solid Spider medium or solid YEPD plus serum transposon insertion proximal to, but not within, the ORF C. albicans orf19.5178 ORF ERG5 CAL0002665 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.5178 ORF ERG5 CAL0002665 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.5178 ORF ERG5 CAL0002665 PMID: 12773383|CGD_REF: CAL0087974 heterozygous diploid, classical genetics (haploinsufficient phenotype assay) null CAI-4 filamentous growth: normal solid Spider medium or solid YEPD plus serum C. albicans orf19.5178 ORF ERG5 CAL0002665 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.5178 ORF ERG5 CAL0002665 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.5178 ORF ERG5 CAL0002665 PMID: 21135205|CGD_REF: CAL0139967 heterozygous diploid, competitive growth (large-scale identification of genes essential for virulence in mouse) repressible CAI-4 virulence: normal mouse intravenous infection C. albicans orf19.5179 ORF LIP5 CAL0002667 PMID: 12773383|CGD_REF: CAL0087974 heterozygous diploid, classical genetics (haploinsufficient phenotype assay) null CAI-4 viable heterozygous deletion C. albicans orf19.5179 ORF LIP5 CAL0002667 PMID: 12773383|CGD_REF: CAL0087974 heterozygous diploid, classical genetics (haploinsufficient phenotype assay) null CAI-4 filamentous growth: decreased solid Spider medium heterozygous deletion C. albicans orf19.5179 ORF LIP5 CAL0002667 PMID: 12773383|CGD_REF: CAL0087974 heterozygous diploid, classical genetics (haploinsufficient phenotype assay) unspecified CAI-4 filamentous growth: decreased solid Spider medium transposon insertion proximal to, but not within, the ORF C. albicans orf19.5180 ORF PRX1 CAL0002689 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.5180 ORF PRX1 CAL0002689 PMID: 22392610|CGD_REF: CAL0000144105 homozygous diploid, classical genetics null CAI-4 viable C. albicans orf19.5180 ORF PRX1 CAL0002689 PMID: 22392610|CGD_REF: CAL0000144105 homozygous diploid, classical genetics null CAI-4 resistance to chemicals: decreased tert-butyl hydroperoxide C. albicans orf19.5181 ORF NIK1 CAL0002691 PMID: 11270409|CGD_REF: CAL0081050 homozygous diploid, classical genetics null Not recorded resistance to chemicals: normal ketoconazole C. albicans orf19.5181 ORF NIK1 CAL0002691 PMID: 11270409|CGD_REF: CAL0081050 homozygous diploid, classical genetics null Not recorded germ tube formation: delayed C. albicans orf19.5181 ORF NIK1 CAL0002691 PMID: 15470110|CGD_REF: CAL0082464 homozygous diploid, classical genetics null Not recorded germ tube formation: normal serum-containing medium C. albicans orf19.5181 ORF NIK1 CAL0002691 PMID: 11270409|CGD_REF: CAL0081050 homozygous diploid, classical genetics null Not recorded resistance to chemicals: normal flucytosine C. albicans orf19.5181 ORF NIK1 CAL0002691 PMID: 11270409|CGD_REF: CAL0081050 homozygous diploid, classical genetics null Not recorded resistance to chemicals: normal miconazole C. albicans orf19.5181 ORF NIK1 CAL0002691 PMID: 14507372|CGD_REF: CAL0088818 heterozygous diploid, large-scale survey (large-scale identification of essential genes by gene replacement and conditional expression (GRACE) method) repressible CAI-4 viable one allele is deleted and the other is placed under repressible Tet promoter C. albicans orf19.5181 ORF NIK1 CAL0002691 PMID: 11270409|CGD_REF: CAL0081050 heterozygous diploid, classical genetics null Not recorded viable C. albicans orf19.5181 ORF NIK1 CAL0002691 PMID: 11270409|CGD_REF: CAL0081050 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.5181 ORF NIK1 CAL0002691 PMID: 9618540|CGD_REF: CAL0081583 heterozygous diploid, classical genetics null Not recorded viable C. albicans orf19.5181 ORF NIK1 CAL0002691 PMID: 9618540|CGD_REF: CAL0081583 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.5181 ORF NIK1 CAL0002691 PMID: 9618540|CGD_REF: CAL0081583 heterozygous diploid, classical genetics null CAI-4 hyphal growth: decreased solid Spider or serum-containing medium phenotype is intermediate between that of wild type and the homozygous null mutant C. albicans orf19.5181 ORF NIK1 CAL0002691 PMID: 9618540|CGD_REF: CAL0081583 homozygous diploid, classical genetics null CAI-4 hyphal growth: decreased solid Spider or serum-containing medium C. albicans orf19.5181 ORF NIK1 CAL0002691 PMID: 10572127|CGD_REF: CAL0081384 homozygous diploid, classical genetics null nik1::hisG-URA3-hisG/nik1::hisG-URA3-hisG CAI-4 hyphal growth: decreased solid YEPD plus serum C. albicans orf19.5181 ORF NIK1 CAL0002691 PMID: 10572127|CGD_REF: CAL0081384 homozygous diploid, classical genetics null nik1::hisG-URA3-hisG/nik1::hisG-URA3-hisG CAI-4 viable C. albicans orf19.5181 ORF NIK1 CAL0002691 PMID: 10572127|CGD_REF: CAL0081384 homozygous diploid, classical genetics null nik1::hisG-URA3-hisG/nik1::hisG-URA3-hisG CAI-4 virulence: decreased mouse intravenous infection C. albicans orf19.5181 ORF NIK1 CAL0002691 PMID: 15470110|CGD_REF: CAL0082464 homozygous diploid, classical genetics null Not recorded oxidative stress resistance: decreased hydrogen peroxide C. albicans orf19.5181 ORF NIK1 CAL0002691 PMID: 11270409|CGD_REF: CAL0081050 homozygous diploid, classical genetics null Not recorded osmotic stress resistance: normal C. albicans orf19.5181 ORF NIK1 CAL0002691 PMID: 9618540|CGD_REF: CAL0081583 homozygous diploid, classical genetics null Not recorded osmotic stress resistance: normal C. albicans orf19.5181 ORF NIK1 CAL0002691 PMID: 11270409|CGD_REF: CAL0081050 homozygous diploid, classical genetics null Not recorded resistance to chemicals: normal amphotericin B C. albicans orf19.5181 ORF NIK1 CAL0002691 PMID: 11270409|CGD_REF: CAL0081050 homozygous diploid, classical genetics null Not recorded resistance to chemicals: normal benomyl C. albicans orf19.5181 ORF NIK1 CAL0002691 PMID: 11270409|CGD_REF: CAL0081050 homozygous diploid, classical genetics null Not recorded resistance to chemicals: normal Cilofungin C. albicans orf19.5181 ORF NIK1 CAL0002691 PMID: 11270409|CGD_REF: CAL0081050 homozygous diploid, classical genetics null Not recorded resistance to chemicals: normal nikkomycin Z C. albicans orf19.5181 ORF NIK1 CAL0002691 PMID: 11270409|CGD_REF: CAL0081050 homozygous diploid, classical genetics null Not recorded resistance to chemicals: normal vinclozolin C. albicans orf19.5181 ORF NIK1 CAL0002691 PMID: 11270409|CGD_REF: CAL0081050 homozygous diploid, classical genetics null Not recorded resistance to chemicals: normal fluconazole C. albicans orf19.5181 ORF NIK1 CAL0002691 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.5181 ORF NIK1 CAL0002691 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.5181 ORF NIK1 CAL0002691 PMID: 11270409|CGD_REF: CAL0081050 heterozygous diploid, classical genetics null Not recorded virulence: decreased mouse intravenous infection C. albicans orf19.5181 ORF NIK1 CAL0002691 PMID: 11270409|CGD_REF: CAL0081050 homozygous diploid, classical genetics null Not recorded virulence: decreased mouse intravenous infection C. albicans orf19.5181 ORF NIK1 CAL0002691 PMID: 11270409|CGD_REF: CAL0081050 homozygous diploid, classical genetics null Not recorded virulence: decreased mouse intravenous infection C. albicans orf19.5181 ORF NIK1 CAL0002691 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.5181 ORF NIK1 CAL0002691 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.5182 ORF POL3 CAL0002693 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.5184 ORF CAL0002697 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.5184 ORF CAL0002697 PMID: 21135205|CGD_REF: CAL0139967 heterozygous diploid, large-scale survey (large-scale identification of genes essential for virulence in mouse) repressible CAI-4 virulence: absent mouse intravenous infection C. albicans orf19.5188 ORF CHS1 CAL0002701 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.5188 ORF CHS1 CAL0002701 PMID: 11251855|CGD_REF: CAL0081010 heterozygous diploid, classical genetics repressible Not recorded hypoosmotic stress resistance: decreased cells lyse C. albicans orf19.5188 ORF CHS1 CAL0002701 PMID: 14507372|CGD_REF: CAL0088818 heterozygous diploid, large-scale survey (large-scale identification of essential genes by gene replacement and conditional expression (GRACE) method) repressible CAI-4 inviable one allele is deleted and the other is placed under repressible Tet promoter C. albicans orf19.5188 ORF CHS1 CAL0002701 PMID: 8636047|CGD_REF: CAL0081006 homozygous diploid, classical genetics null Not recorded inviable homozygous null mutant strain could not be recovered, suggesting that the gene is essential under the selection conditions C. albicans orf19.5188 ORF CHS1 CAL0002701 PMID: 11251855|CGD_REF: CAL0081010 heterozygous diploid, classical genetics repressible Not recorded inviable C. albicans orf19.5188 ORF CHS1 CAL0002701 PMID: 11251855|CGD_REF: CAL0081010 heterozygous diploid, classical genetics repressible Not recorded cytokinesis: decreased cells form chains which lack septa C. albicans orf19.5188 ORF CHS1 CAL0002701 PMID: 19222370|CGD_REF: CAL0122389 homozygous diploid, classical genetics null CAI-4 induction of host response: decreased Human peripheral blood mononuclear cells (PBMCs) stimulated with the mutant released significantly lower amounts of IL-1beta C. albicans orf19.5188 ORF CHS1 CAL0002701 PMID: 11251855|CGD_REF: CAL0081010 heterozygous diploid, classical genetics repressible Not recorded virulence: absent mouse intravenous infection C. albicans orf19.5188 ORF CHS1 CAL0002701 PMID: 21135205|CGD_REF: CAL0139967 heterozygous diploid, large-scale survey (large-scale identification of genes essential for virulence in mouse) repressible CAI-4 virulence: absent mouse intravenous infection C. albicans orf19.5191 ORF FGR6-1 CAL0002724 PMID: 12773383|CGD_REF: CAL0087974 heterozygous diploid, classical genetics (haploinsufficient phenotype assay) null CAI-4 viable heterozygous transposon insertion C. albicans orf19.5195 ORF URA6 CAL0002732 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.5196 ORF ESS1 CAL0002734 PMID: 11805043|CGD_REF: CAL0081062 heterozygous diploid, classical genetics null CAI-4 germ tube formation: decreased liquid Lee's medium at 37 deg C severe decrease; smaller decreases observed in Spider and serum-containing media at 37 deg C C. albicans orf19.5196 ORF ESS1 CAL0002734 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.5196 ORF ESS1 CAL0002734 PMID: 14507372|CGD_REF: CAL0088818 heterozygous diploid, large-scale survey (large-scale identification of essential genes by gene replacement and conditional expression (GRACE) method) repressible CAI-4 viable one allele is deleted and the other is placed under repressible Tet promoter C. albicans orf19.5196 ORF ESS1 CAL0002734 PMID: 11805043|CGD_REF: CAL0081062 heterozygous diploid, classical genetics null CAI-4 viable C. albicans orf19.5196 ORF ESS1 CAL0002734 PMID: 11805043|CGD_REF: CAL0081062 heterozygous diploid, classical genetics conditional ess1-H171R/ess1 deletion CAI-4 filamentous growth: absent solid Lee's or Spider media at 37 deg C C. albicans orf19.5196 ORF ESS1 CAL0002734 PMID: 11805043|CGD_REF: CAL0081062 heterozygous diploid, classical genetics conditional ess1-H171R/ess1 deletion CAI-4 germ tube formation: decreased liquid Lee's medium at 37 deg C severe decrease; smaller decreases observed in Spider and serum-containing media at 37 deg C C. albicans orf19.5196 ORF ESS1 CAL0002734 PMID: 11805043|CGD_REF: CAL0081062 heterozygous diploid, classical genetics conditional ess1-H171R/ess1 deletion CAI-4 heat sensitivity: increased elevated temperature (37 deg C) cells arrest in late mitosis, after nuclear division, at nonpermissive temperature C. albicans orf19.5196 ORF ESS1 CAL0002734 PMID: 11805043|CGD_REF: CAL0081062 heterozygous diploid, classical genetics conditional ess1-H171R/ess1 deletion CAI-4 vegetative growth: decreased rate permissive temperature (30 deg C) cells arrest in late mitosis, after nuclear division, at nonpermissive temperature C. albicans orf19.5196 ORF ESS1 CAL0002734 PMID: 11805043|CGD_REF: CAL0081062 homozygous diploid, classical genetics null CAI-4 inviable homozygous null mutant strain could not be recovered, suggesting that the gene is essential under the selection conditions C. albicans orf19.5196 ORF ESS1 CAL0002734 PMID: 11805043|CGD_REF: CAL0081062 homozygous diploid, classical genetics null CAI-4 filamentous growth: absent solid Lee's or Spider media at 37 deg C C. albicans orf19.5196 ORF ESS1 CAL0002734 PMID: 15835905|CGD_REF: CAL0104094 heterozygous diploid, classical genetics conditional Not recorded virulence: decreased H171R/null heterozygous mutant, heat sensitive mouse intravenous infection C. albicans orf19.5196 ORF ESS1 CAL0002734 PMID: 15835905|CGD_REF: CAL0104094 heterozygous diploid, classical genetics null Not recorded virulence: decreased mouse intravenous infection C. albicans orf19.5197 ORF APE2 CAL0002735 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.5198 ORF NOP4 CAL0002736 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, competitive growth (haploinsufficient phenotype assay, barcode deletion set) null SC5314 resistance to chemicals: decreased 5-fluorouracil C. albicans orf19.5198 ORF NOP4 CAL0002736 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, competitive growth (haploinsufficient phenotype assay, barcode deletion set) null SC5314 resistance to chemicals: decreased tubercidin C. albicans orf19.5198 ORF NOP4 CAL0002736 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, competitive growth (haploinsufficient phenotype assay, barcode deletion set) null SC5314 resistance to chemicals: decreased flucytosine C. albicans orf19.5198 ORF NOP4 CAL0002736 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.5198 ORF NOP4 CAL0002736 PMID: 20494978|CGD_REF: CAL0125636 heterozygous diploid, classical genetics null BWP17 resistance to chemicals: decreased clotrimazole (75 uM) growth in liquid culture confirmation of mutant phenotypes for heterozygous transposon insertion strains showing sensitivity in a large-scale assay C. albicans orf19.52 ORF CAL0000602 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.5200 ORF SIT4 CAL0003480 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.5200 ORF SIT4 CAL0003480 PMID: 18708562|CGD_REF: CAL0119375 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.5200 ORF SIT4 CAL0003480 PMID: 14731272|CGD_REF: CAL0081394 homozygous diploid, classical genetics null RM1000 hyphal growth: absent Lee's, Spider, SLAD, and serum-containing media C. albicans orf19.5200 ORF SIT4 CAL0003480 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.5200 ORF SIT4 CAL0003480 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: abnormal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.5200 ORF SIT4 CAL0003480 PMID: 18708562|CGD_REF: CAL0119375 homozygous diploid, classical genetics null Not recorded virulence: decreased insect infection C. albicans orf19.5200 ORF SIT4 CAL0003480 PMID: 14731272|CGD_REF: CAL0081394 homozygous diploid, classical genetics null Not recorded virulence: decreased mouse intravenous infection C. albicans orf19.5200 ORF SIT4 CAL0003480 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.5200 ORF SIT4 CAL0003480 PMID: 20457806|CGD_REF: CAL0125442 homozygous diploid, classical genetics null RM1000 hyphal growth: decreased liquid M199 pH 8 medium at 37 deg C hyphal growth defect is severe and is partially rescued by treatment with 5 nM rapamycin C. albicans orf19.5200 ORF SIT4 CAL0003480 PMID: 20457806|CGD_REF: CAL0125442 homozygous diploid, classical genetics null RM1000 alkaline pH resistance: decreased YPD medium, pH 9 C. albicans orf19.5200 ORF SIT4 CAL0003480 PMID: 20457806|CGD_REF: CAL0125442 homozygous diploid, classical genetics null RM1000 resistance to chemicals: increased rapamycin (10 nM) YPD or Spider media C. albicans orf19.5200 ORF SIT4 CAL0003480 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.5205 ORF CAL0003485 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.5206 ORF CAL0003486 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.5207 ORF CAL0003487 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.5207 ORF CAL0003487 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.5207 ORF CAL0003487 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.5207 ORF CAL0003487 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.5209 ORF CAL0003489 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.5219 ORF IRA2 CAL0003508 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.522 ORF PIM1 CAL0000116 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.5221 ORF CAL0003519 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.5224 ORF PKH2 CAL0003522 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.5224 ORF PKH2 CAL0003522 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.5224 ORF PKH2 CAL0003522 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.5224 ORF PKH2 CAL0003522 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.5224 ORF PKH2 CAL0003522 PMID: 23911092|CGD_REF: CAL0000172636 heterozygous diploid, classical genetics null Other C. albicans viable C. albicans orf19.5224 ORF PKH2 CAL0003522 PMID: 23911092|CGD_REF: CAL0000172636 heterozygous diploid, classical genetics null Other C. albicans chemical compound accumulation: decreased glycogen C. albicans orf19.5224 ORF PKH2 CAL0003522 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.5226 ORF WRS1 CAL0003524 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.5228 ORF RIB3 CAL0003526 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.5229 ORF CAL0003527 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.5231 ORF CAL0003536 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 invasive growth: decreased solid SLAD media C. albicans orf19.5232 ORF CSI2 CAL0003537 PMID: 12773383|CGD_REF: CAL0087974 heterozygous diploid, classical genetics (haploinsufficient phenotype assay) null CAI-4 viable heterozygous transposon insertion C. albicans orf19.5232 ORF CSI2 CAL0003537 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.5232 ORF CSI2 CAL0003537 PMID: 16607011|CGD_REF: CAL0115846 heterozygous diploid, classical genetics null SC5314 viable C. albicans orf19.5232 ORF CSI2 CAL0003537 PMID: 16607011|CGD_REF: CAL0115846 homozygous diploid, classical genetics null SC5314 inviable homozygous null mutant strain could not be recovered, suggesting that the gene is essential under the selection conditions C. albicans orf19.5232 ORF CSI2 CAL0003537 PMID: 16607011|CGD_REF: CAL0115846 heterozygous diploid, classical genetics repressible SC5314 inviable C. albicans orf19.5232 ORF CSI2 CAL0003537 PMID: 12773383|CGD_REF: CAL0087974 heterozygous diploid, classical genetics (haploinsufficient phenotype assay) null CAI-4 filamentous growth: decreased solid Spider medium heterozygous transposon insertion C. albicans orf19.5232 ORF CSI2 CAL0003537 PMID: 21135205|CGD_REF: CAL0139967 heterozygous diploid, competitive growth (large-scale identification of genes essential for virulence in mouse) repressible CAI-4 virulence: decreased mouse intravenous infection C. albicans orf19.5234 ORF RBD1 CAL0003539 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.5234 ORF RBD1 CAL0003539 PMID: 15701792|CGD_REF: CAL0082331 heterozygous diploid, classical genetics null Not recorded viable C. albicans orf19.5234 ORF RBD1 CAL0003539 PMID: 15701792|CGD_REF: CAL0082331 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.5234 ORF RBD1 CAL0003539 PMID: 15701792|CGD_REF: CAL0082331 homozygous diploid, classical genetics null RM1000 filamentous growth: abnormal solid Spider medium at 30 deg C increased peripheral filamentation, and decreased central area of colony C. albicans orf19.5234 ORF RBD1 CAL0003539 PMID: 15701792|CGD_REF: CAL0082331 heterozygous diploid, classical genetics null RM1000 filamentous growth: abnormal solid Spider medium at 30 deg C increased peripheral filamentation, and decreased central area of colony; phenotype is intermediate between wild type and homozygous null mutant C. albicans orf19.5234 ORF RBD1 CAL0003539 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: decreased growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.5234 ORF RBD1 CAL0003539 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: abnormal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.5234 ORF RBD1 CAL0003539 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.5234 ORF RBD1 CAL0003539 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.5235 ORF CAL0003540 PMID: 14663094|CGD_REF: CAL0080633 homozygous diploid, systematic mutation set (homozygous insertion mutants generated with URA3-ARG4-URA3 (UAU1) cassette) null BWP17 viable C. albicans orf19.5238 ORF CAL0003543 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.524 ORF CAL0000119 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.524 ORF CAL0000119 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.524 ORF CAL0000119 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: decreased rate liquid synthetic complete medium C. albicans orf19.524 ORF CAL0000119 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.5241 ORF SNT1 CAL0003554 PMID: 12773383|CGD_REF: CAL0087974 heterozygous diploid, classical genetics (haploinsufficient phenotype assay) null CAI-4 viable heterozygous transposon insertion C. albicans orf19.5241 ORF SNT1 CAL0003554 PMID: 14663094|CGD_REF: CAL0080633 homozygous diploid, systematic mutation set (homozygous insertion mutants generated with URA3-ARG4-URA3 (UAU1) cassette) null BWP17 viable C. albicans orf19.5241 ORF SNT1 CAL0003554 PMID: 12773383|CGD_REF: CAL0087974 heterozygous diploid, classical genetics (haploinsufficient phenotype assay) null CAI-4 filamentous growth: increased solid Spider medium heterozygous transposon insertion C. albicans orf19.5241 ORF SNT1 CAL0003554 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: decreased growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.5241 ORF SNT1 CAL0003554 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: abnormal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.5241 ORF SNT1 CAL0003554 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.5241 ORF SNT1 CAL0003554 PMID: 20485517|CGD_REF: CAL0125674 homozygous diploid, classical genetics null SN152 filamentous growth: increased MTL a/alpha cells, YPD medium, elevated temperature wrinkled colonies composed of mostly true hyphae C. albicans orf19.5241 ORF SNT1 CAL0003554 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.5242 ORF CDC6 CAL0003555 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.5243 ORF TRP3 CAL0003556 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.5244 ORF MCD4 CAL0003557 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.5247 ORF CAL0003560 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.5247 ORF CAL0003560 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.5247 ORF CAL0003560 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.5247 ORF CAL0003560 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.5248 ORF MSO1 CAL0003561 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient YPD medium C. albicans orf19.5248 ORF MSO1 CAL0003561 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient SLAD medium C. albicans orf19.5251 ORF ZCF30 CAL0003564 PMID: 14663094|CGD_REF: CAL0080633 homozygous diploid, systematic mutation set (homozygous insertion mutants generated with URA3-ARG4-URA3 (UAU1) cassette) null BWP17 viable C. albicans orf19.5251 ORF ZCF30 CAL0003564 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.5251 ORF ZCF30 CAL0003564 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.5251 ORF ZCF30 CAL0003564 PMID: 22073120|CGD_REF: CAL0000143592 homozygous diploid, classical genetics null BWP17 viable C. albicans orf19.5251 ORF ZCF30 CAL0003564 PMID: 22073120|CGD_REF: CAL0000143592 homozygous diploid, classical genetics null BWP17 invasive growth: decreased decreased agar invasion C. albicans orf19.5251 ORF ZCF30 CAL0003564 PMID: 22073120|CGD_REF: CAL0000143592 homozygous diploid, classical genetics null BWP17 viable C. albicans orf19.5251 ORF ZCF30 CAL0003564 PMID: 22073120|CGD_REF: CAL0000143592 homozygous diploid, classical genetics null BWP17 colony appearance: abnormal decreased colony wrinkling C. albicans orf19.5251 ORF ZCF30 CAL0003564 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.5251 ORF ZCF30 CAL0003564 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.5253 ORF CAL0003566 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.5255 ORF PXA2 CAL0003568 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.5257 ORF LCB4 CAL0003570 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.5257 ORF LCB4 CAL0003570 PMID: 22354293|CGD_REF: CAL0000144046 heterozygous diploid, classical genetics null Other C. albicans resistance to chemicals: decreased miconazole C. albicans orf19.5258 ORF CAL0003571 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.5258 ORF CAL0003571 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.5258 ORF CAL0003571 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.5258 ORF CAL0003571 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.526 ORF NHP2 CAL0000123 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.5260 ORF RPN2 CAL0003585 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.5263 ORF SER33 CAL0003590 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.5265 ORF KIP4 CAL0003594 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.5265 ORF KIP4 CAL0003594 PMID: 12773383|CGD_REF: CAL0087974 heterozygous diploid, classical genetics (haploinsufficient phenotype assay) unspecified CAI-4 filamentous growth: increased solid Spider medium transposon insertion proximal to, but not within, the ORF C. albicans orf19.5268 ORF MED10 CAL0003598 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.5274 ORF CAL0003618 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.5277 ORF CAL0003622 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 invasive growth: decreased solid SLAD media C. albicans orf19.528 ORF SEC26 CAL0000129 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.5280 ORF MUP1 CAL0003639 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.5280 ORF MUP1 CAL0003639 PMID: 21414038|CGD_REF: CAL0141808 homozygous diploid, classical genetics null BWP17 viable C. albicans orf19.5280 ORF MUP1 CAL0003639 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient YPD medium C. albicans orf19.5280 ORF MUP1 CAL0003639 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient YNB medium C. albicans orf19.5280 ORF MUP1 CAL0003639 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient SLAD medium C. albicans orf19.5281 ORF CAL0003641 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.5282 ORF CAL0003643 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 invasive growth: decreased solid SLAD media C. albicans orf19.5285 ORF PST3 CAL0003649 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.5285 ORF PST3 CAL0003649 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.5285 ORF PST3 CAL0003649 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.5285 ORF PST3 CAL0003649 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.5286 ORF YCP4 CAL0003651 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.5286 ORF YCP4 CAL0003651 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.5286 ORF YCP4 CAL0003651 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.5286 ORF YCP4 CAL0003651 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.529 ORF CAL0000133 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: decreased growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.529 ORF CAL0000133 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.529 ORF CAL0000133 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.529 ORF CAL0000133 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.5291 ORF CAL0003671 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.5291 ORF CAL0003671 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.5291 ORF CAL0003671 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.5291 ORF CAL0003671 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.5291 ORF CAL0003671 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.5291 ORF CAL0003671 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 invasive growth: decreased solid SLAD media C. albicans orf19.5292 ORF AXL2 CAL0003673 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.5292 ORF AXL2 CAL0003673 PMID: 14663094|CGD_REF: CAL0080633 homozygous diploid, systematic mutation set (homozygous insertion mutants generated with URA3-ARG4-URA3 (UAU1) cassette) null BWP17 viable C. albicans orf19.5292 ORF AXL2 CAL0003673 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient YPD medium C. albicans orf19.5292 ORF AXL2 CAL0003673 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient SC medium C. albicans orf19.5293 ORF CAL0003675 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.5295 ORF CAL0003679 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.5297 ORF CAL0003682 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.5297 ORF CAL0003682 PMID: 21135205|CGD_REF: CAL0139967 heterozygous diploid, large-scale survey (large-scale identification of genes essential for virulence in mouse) repressible CAI-4 virulence: absent mouse intravenous infection C. albicans orf19.5299 ORF ECM1 CAL0003683 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.530 ORF CAL0000154 PMID: 14663094|CGD_REF: CAL0080633 homozygous diploid, systematic mutation set (homozygous insertion mutants generated with URA3-ARG4-URA3 (UAU1) cassette) null BWP17 viable C. albicans orf19.5300 ORF CAL0004243 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.5300 ORF CAL0004243 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.5300 ORF CAL0004243 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: abnormal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.5300 ORF CAL0004243 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: decreased rate liquid synthetic complete medium C. albicans orf19.5300 ORF CAL0004243 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.5302 ORF PGA31 CAL0004244 PMID: 18765290|CGD_REF: CAL0119430 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased Calcofluor White C. albicans orf19.5302 ORF PGA31 CAL0004244 PMID: 18765290|CGD_REF: CAL0119430 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.5302 ORF PGA31 CAL0004244 PMID: 18765290|CGD_REF: CAL0119430 homozygous diploid, classical genetics null Not recorded cell wall morphology: abnormal decreased thickness C. albicans orf19.5302 ORF PGA31 CAL0004244 PMID: 18765290|CGD_REF: CAL0119430 homozygous diploid, classical genetics null Not recorded chitin deposition: decreased C. albicans orf19.5302 ORF PGA31 CAL0004244 PMID: 18765290|CGD_REF: CAL0119430 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased caspofungin C. albicans orf19.5303 ORF PGA30 CAL0004245 PMID: 18765290|CGD_REF: CAL0119430 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.5303 ORF PGA30 CAL0004245 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 invasive growth: decreased solid SLAD media C. albicans orf19.5305 ORF RHD3 CAL0004247 PMID: 20533408|CGD_REF: CAL0125506 homozygous diploid, classical genetics null BWP17 induction of host response: decreased mutant induces reduced mRNA levels of the cytokines GM-CSF, TNF, IL-1beta, IL-6 and IL-8 C. albicans orf19.5305 ORF RHD3 CAL0004247 PMID: 20533408|CGD_REF: CAL0125506 homozygous diploid, classical genetics null BWP17 viable C. albicans orf19.5305 ORF RHD3 CAL0004247 PMID: 20533408|CGD_REF: CAL0125506 homozygous diploid, classical genetics null BWP17 cell wall morphology: abnormal reduced level of mannose in the cell wall C. albicans orf19.5305 ORF RHD3 CAL0004247 PMID: 20533408|CGD_REF: CAL0125506 homozygous diploid, classical genetics null BWP17 virulence: decreased in vitro model of infection (reconstituted human epithelium) C. albicans orf19.5307 ORF JEN2 CAL0004249 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.5307 ORF JEN2 CAL0004249 PMID: 19968788|CGD_REF: CAL0124718 homozygous diploid, classical genetics null jen2::HIS1/jen2::URA3 RM1000 viable C. albicans orf19.5307 ORF JEN2 CAL0004249 PMID: 19968788|CGD_REF: CAL0124718 homozygous diploid, classical genetics null jen2::HIS1/jen2::URA3 RM1000 nutrient uptake: decreased rate succinic acid C. albicans orf19.5307 ORF JEN2 CAL0004249 PMID: 19968788|CGD_REF: CAL0124718 homozygous diploid, classical genetics null jen2::HIS1/jen2::URA3 RM1000 nutrient uptake: decreased rate malic acid C. albicans orf19.5307 ORF JEN2 CAL0004249 PMID: 19968788|CGD_REF: CAL0124718 homozygous diploid, classical genetics null jen2::HIS1/jen2::URA3 RM1000 nutrient uptake: normal rate lactic acid C. albicans orf19.5307 ORF JEN2 CAL0004249 PMID: 19968788|CGD_REF: CAL0124718 homozygous diploid, classical genetics null jen2::HIS1/jen2::URA3 RM1000 utilization of carbon source: decreased succinic acid C. albicans orf19.5307 ORF JEN2 CAL0004249 PMID: 19968788|CGD_REF: CAL0124718 homozygous diploid, classical genetics null jen2::HIS1/jen2::URA3 RM1000 utilization of carbon source: decreased malic acid C. albicans orf19.5307 ORF JEN2 CAL0004249 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient SLAD medium C. albicans orf19.5307 ORF JEN2 CAL0004249 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 invasive growth: decreased solid SLAD media C. albicans orf19.5308 ORF CAL0004250 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 invasive growth: decreased solid SLAD media C. albicans orf19.5312 ORF MET4 CAL0004261 PMID: 22359502|CGD_REF: CAL0000144048 homozygous diploid, classical genetics null BWP17 viable independent insertion mutant isolates C. albicans orf19.5312 ORF MET4 CAL0004261 PMID: 22359502|CGD_REF: CAL0000144048 homozygous diploid, classical genetics null BWP17 adhesion: decreased independent insertion mutant isolates C. albicans orf19.5316 ORF FGR29 CAL0004265 PMID: 12773383|CGD_REF: CAL0087974 heterozygous diploid, classical genetics (haploinsufficient phenotype assay) null CAI-4 viable heterozygous transposon insertion C. albicans orf19.5316 ORF FGR29 CAL0004265 PMID: 12773383|CGD_REF: CAL0087974 heterozygous diploid, classical genetics (haploinsufficient phenotype assay) null CAI-4 filamentous growth: decreased solid Spider medium heterozygous transposon insertion C. albicans orf19.532 ORF RBR2 CAL0000157 PMID: 17873081|CGD_REF: CAL0118685 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.5323 ORF MDH1-3 CAL0004279 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 invasive growth: decreased solid SLAD media C. albicans orf19.5325 ORF KIN3 CAL0004280 PMID: 20140194|CGD_REF: CAL0124995 homozygous diploid, classical genetics null Other C. albicans viable C. albicans orf19.5325 ORF KIN3 CAL0004280 PMID: 20140194|CGD_REF: CAL0124995 homozygous diploid, classical genetics null Other C. albicans resistance to chemicals: decreased caspofungin C. albicans orf19.5325 ORF KIN3 CAL0004280 PMID: 20140194|CGD_REF: CAL0124995 homozygous diploid, classical genetics null Other C. albicans protein/peptide distribution: abnormal Sep7-GFP C. albicans orf19.5326 ORF CAL0004281 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.5326 ORF CAL0004281 PMID: 15964282|CGD_REF: CAL0114274 homozygous diploid, systematic mutation set (split-marker transposon insertion strategy to disrupt both alleles) null BWP17 viable C. albicans orf19.5326 ORF CAL0004281 PMID: 19463063|CGD_REF: CAL0123630 homozygous diploid, systematic mutation set (split-marker transposon insertion strategy to disrupt both alleles) null BWP17 viable C. albicans orf19.5326 ORF CAL0004281 PMID: 15964282|CGD_REF: CAL0114274 homozygous diploid, systematic mutation set (split-marker transposon insertion strategy to disrupt both alleles) null BWP17 biofilm formation: normal C. albicans orf19.5326 ORF CAL0004281 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.5326 ORF CAL0004281 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.5326 ORF CAL0004281 PMID: 19463063|CGD_REF: CAL0123630 homozygous diploid, systematic mutation set (split-marker transposon insertion strategy to disrupt both alleles) null BWP17 virulence: normal Toll mutant D. melanogaster invasive infection insect infection C. albicans orf19.5326 ORF CAL0004281 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.5326 ORF CAL0004281 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.5328 ORF GCN1 CAL0004282 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient SC medium C. albicans orf19.5334 ORF CAL0004295 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.5334 ORF CAL0004295 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.5334 ORF CAL0004295 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.5334 ORF CAL0004295 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.5335 ORF SGS1 CAL0004296 PMID: 18691183|CGD_REF: CAL0119368 heterozygous diploid, classical genetics null BWP17 viable C. albicans orf19.5335 ORF SGS1 CAL0004296 PMID: 21511048|CGD_REF: CAL0141918 homozygous diploid, classical genetics null sgs1::CdHIS1/sgs1::CdARG4 Other C. albicans viable slow growth phenotype C. albicans orf19.5335 ORF SGS1 CAL0004296 PMID: 21511048|CGD_REF: CAL0141918 homozygous diploid, classical genetics null sgs1::CdHIS1/sgs1::CdARG4 Other C. albicans filamentous growth: abnormal YEPD + uri agar at 30 degrees C mutants produce wrinkled colonies with pseudohyphal-like cells C. albicans orf19.5335 ORF SGS1 CAL0004296 PMID: 21511048|CGD_REF: CAL0141918 homozygous diploid, classical genetics null sgs1::CdHIS1/sgs1::CdARG4 Other C. albicans resistance to chemicals: decreased tetrabutyl hydrogen peroxide (2 mM) C. albicans orf19.5335 ORF SGS1 CAL0004296 PMID: 21511048|CGD_REF: CAL0141918 homozygous diploid, classical genetics null sgs1::CdHIS1/sgs1::CdARG4 Other C. albicans resistance to chemicals: decreased camptothecin (100 micromolar) C. albicans orf19.5335 ORF SGS1 CAL0004296 PMID: 21511048|CGD_REF: CAL0141918 homozygous diploid, classical genetics null sgs1::CdHIS1/sgs1::CdARG4 Other C. albicans resistance to chemicals: decreased ethylmethane sulfonate (0.03%) C. albicans orf19.5335 ORF SGS1 CAL0004296 PMID: 21511048|CGD_REF: CAL0141918 homozygous diploid, classical genetics null sgs1::CdHIS1/sgs1::CdARG4 Other C. albicans resistance to chemicals: decreased methyl methanesulfonate (0.01%) C. albicans orf19.5335 ORF SGS1 CAL0004296 PMID: 21511048|CGD_REF: CAL0141918 homozygous diploid, classical genetics null sgs1::CdHIS1/sgs1::CdARG4 Other C. albicans resistance to chemicals: decreased hydroxyurea (20 mM) C. albicans orf19.5335 ORF SGS1 CAL0004296 PMID: 21511048|CGD_REF: CAL0141918 homozygous diploid, classical genetics null sgs1::CdHIS1/sgs1::CdARG4 Other C. albicans UV resistance: decreased C. albicans orf19.5335 ORF SGS1 CAL0004296 PMID: 21511048|CGD_REF: CAL0141918 homozygous diploid, classical genetics null sgs1::CdHIS1/sgs1::CdARG4 Other C. albicans resistance to chemicals: decreased fluconazole C. albicans orf19.5335 ORF SGS1 CAL0004296 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 invasive growth: decreased solid SLAD media C. albicans orf19.5337 ORF UBC15 CAL0004297 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.5338 ORF GAL4 CAL0004298 PMID: 17555439|CGD_REF: CAL0117968 homozygous diploid, classical genetics null Not recorded survival rate in stationary phase: decreased C. albicans orf19.5338 ORF GAL4 CAL0004298 PMID: 15964282|CGD_REF: CAL0114274 homozygous diploid, systematic mutation set (split-marker transposon insertion strategy to disrupt both alleles) null BWP17 viable C. albicans orf19.5338 ORF GAL4 CAL0004298 PMID: 17540568|CGD_REF: CAL0117978 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.5338 ORF GAL4 CAL0004298 PMID: 15964282|CGD_REF: CAL0114274 homozygous diploid, systematic mutation set (split-marker transposon insertion strategy to disrupt both alleles) null BWP17 biofilm formation: normal C. albicans orf19.5338 ORF GAL4 CAL0004298 PMID: 17540568|CGD_REF: CAL0117978 homozygous diploid, classical genetics null Not recorded utilization of carbon source: normal ethanol C. albicans orf19.5338 ORF GAL4 CAL0004298 PMID: 17540568|CGD_REF: CAL0117978 homozygous diploid, classical genetics null Not recorded utilization of carbon source: normal D-glucose C. albicans orf19.5338 ORF GAL4 CAL0004298 PMID: 17540568|CGD_REF: CAL0117978 homozygous diploid, classical genetics null Not recorded utilization of carbon source: normal glycerol C. albicans orf19.5338 ORF GAL4 CAL0004298 PMID: 17540568|CGD_REF: CAL0117978 homozygous diploid, classical genetics null Not recorded utilization of carbon source: normal galactose C. albicans orf19.5338 ORF GAL4 CAL0004298 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.5338 ORF GAL4 CAL0004298 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.5338 ORF GAL4 CAL0004298 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.5338 ORF GAL4 CAL0004298 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.5341 ORF RPS4A CAL0004310 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.5341 ORF RPS4A CAL0004310 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 invasive growth: decreased solid SLAD media C. albicans orf19.5342 ORF CAL0004311 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.5342 ORF CAL0004311 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.5342 ORF CAL0004311 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.5342 ORF CAL0004311 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.5343 ORF ASH1 CAL0004312 PMID: 12446785|CGD_REF: CAL0080783 homozygous diploid, classical genetics null CAI-4 germ tube formation: normal liquid serum-containing medium C. albicans orf19.5343 ORF ASH1 CAL0004312 PMID: 12436263|CGD_REF: CAL0081506 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.5343 ORF ASH1 CAL0004312 PMID: 12446785|CGD_REF: CAL0080783 heterozygous diploid, classical genetics null Not recorded viable C. albicans orf19.5343 ORF ASH1 CAL0004312 PMID: 12446785|CGD_REF: CAL0080783 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.5343 ORF ASH1 CAL0004312 PMID: 19779551|CGD_REF: CAL0124331 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.5343 ORF ASH1 CAL0004312 PMID: 12446785|CGD_REF: CAL0080783 homozygous diploid, classical genetics null CAI-4 hyphal growth: decreased solid Lee's medium, neutral pH severe decrease C. albicans orf19.5343 ORF ASH1 CAL0004312 PMID: 12446785|CGD_REF: CAL0080783 homozygous diploid, classical genetics null CAI-4 hyphal growth: decreased solid YPD plus serum slight decrease C. albicans orf19.5343 ORF ASH1 CAL0004312 PMID: 12436263|CGD_REF: CAL0081506 homozygous diploid, classical genetics null CAI-4 invasive growth: decreased solid SLAD or embedded in agar C. albicans orf19.5343 ORF ASH1 CAL0004312 PMID: 12436263|CGD_REF: CAL0081506 heterozygous diploid, classical genetics overexpression CAI-4 invasive growth: increased solid SLAD or embedded in agar C. albicans orf19.5343 ORF ASH1 CAL0004312 PMID: 19779551|CGD_REF: CAL0124331 homozygous diploid, classical genetics null Not recorded colony appearance: abnormal solid Spider medium C. albicans orf19.5343 ORF ASH1 CAL0004312 PMID: 12446785|CGD_REF: CAL0080783 heterozygous diploid, classical genetics null RM1000 filamentous growth: decreased solid Spider medium C. albicans orf19.5343 ORF ASH1 CAL0004312 PMID: 12446785|CGD_REF: CAL0080783 homozygous diploid, classical genetics null RM1000 filamentous growth: decreased solid Spider medium C. albicans orf19.5343 ORF ASH1 CAL0004312 PMID: 12446785|CGD_REF: CAL0080783 heterozygous diploid, classical genetics null Not recorded virulence: decreased virulence is intermediate between that of the homozygous null mutant and wild type mouse intravenous infection C. albicans orf19.5343 ORF ASH1 CAL0004312 PMID: 12446785|CGD_REF: CAL0080783 homozygous diploid, classical genetics null Not recorded virulence: decreased mouse intravenous infection C. albicans orf19.5343 ORF ASH1 CAL0004312 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 invasive growth: decreased solid SLAD media C. albicans orf19.5346 ORF CAL0004317 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.535 ORF RBR1 CAL0000162 PMID: 15189998|CGD_REF: CAL0081438 heterozygous diploid, classical genetics null Not recorded viable wild-type growth rate C. albicans orf19.535 ORF RBR1 CAL0000162 PMID: 15189998|CGD_REF: CAL0081438 homozygous diploid, classical genetics null Not recorded viable wild-type growth rate C. albicans orf19.535 ORF RBR1 CAL0000162 PMID: 15189998|CGD_REF: CAL0081438 homozygous diploid, classical genetics null CAI-4 filamentous growth: decreased low pH C. albicans orf19.5350 ORF CAL0004325 PMID: 23856128|CGD_REF: CAL0000172540 homozygous diploid, classical genetics null BWP17 resistance to chemicals: decreased propolis C. albicans orf19.5351 ORF TIF11 CAL0004326 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.5351 ORF TIF11 CAL0004326 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, competitive growth (haploinsufficient phenotype assay, barcode deletion set) null SC5314 resistance to chemicals: decreased verrucarin C. albicans orf19.5351 ORF TIF11 CAL0004326 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, competitive growth (haploinsufficient phenotype assay, barcode deletion set) null SC5314 resistance to chemicals: decreased roridin A C. albicans orf19.5352 ORF CAL0004327 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.5352 ORF CAL0004327 PMID: 14663094|CGD_REF: CAL0080633 homozygous diploid, systematic mutation set (homozygous insertion mutants generated with URA3-ARG4-URA3 (UAU1) cassette) null BWP17 viable C. albicans orf19.5352 ORF CAL0004327 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.5352 ORF CAL0004327 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.5352 ORF CAL0004327 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.5352 ORF CAL0004327 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.5353 ORF CAL0004328 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 invasive growth: decreased solid SLAD media C. albicans orf19.5356 ORF CAL0004331 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.5356 ORF CAL0004331 PMID: 21135205|CGD_REF: CAL0139967 heterozygous diploid, large-scale survey (large-scale identification of genes essential for virulence in mouse) repressible CAI-4 virulence: absent mouse intravenous infection C. albicans orf19.5357 ORF AKL1 CAL0004333 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.5358 ORF CAL0004335 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.536 ORF CAL0000165 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.5360 ORF RPC11 CAL0004345 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.5360 ORF RPC11 CAL0004345 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 invasive growth: decreased solid SLAD media C. albicans orf19.5362 ORF PSO2 CAL0004348 PMID: 16950924|CGD_REF: CAL0116772 heterozygous diploid, classical genetics null Not recorded viable C. albicans orf19.5362 ORF PSO2 CAL0004348 PMID: 16950924|CGD_REF: CAL0116772 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.5362 ORF PSO2 CAL0004348 PMID: 16950924|CGD_REF: CAL0116772 heterozygous diploid, classical genetics null Not recorded phenotypic switching: normal white-to-opaque switching C. albicans orf19.5362 ORF PSO2 CAL0004348 PMID: 16950924|CGD_REF: CAL0116772 homozygous diploid, classical genetics null Not recorded phenotypic switching: normal white-to-opaque switching C. albicans orf19.5363 ORF CAL0004350 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.5363 ORF CAL0004350 PMID: 21135205|CGD_REF: CAL0139967 heterozygous diploid, competitive growth (large-scale identification of genes essential for virulence in mouse) repressible CAI-4 virulence: decreased mouse intravenous infection C. albicans orf19.5364 ORF CAL0004353 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.5365 ORF CAL0004355 PMID: 14663094|CGD_REF: CAL0080633 homozygous diploid, systematic mutation set (homozygous insertion mutants generated with URA3-ARG4-URA3 (UAU1) cassette) null BWP17 viable C. albicans orf19.5367 ORF RDH54 CAL0004359 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.5368 ORF CAL0004361 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient YPD medium C. albicans orf19.5369 ORF CAL0004363 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.5370 ORF CAL0004370 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.5377 ORF HOS2 CAL0004384 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.5377 ORF HOS2 CAL0004384 PMID: 19555456|CGD_REF: CAL0123821 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.5377 ORF HOS2 CAL0004384 PMID: 19555456|CGD_REF: CAL0123821 homozygous diploid, classical genetics null Not recorded phenotypic switching: decreased MTLa/MTLa background white-to-opaque switching C. albicans orf19.5377 ORF HOS2 CAL0004384 PMID: 20730094|CGD_REF: CAL0126184 homozygous diploid, classical genetics null hos2/hos2 (Tn7::UAU1 disruption) BWP17 viable C. albicans orf19.5377 ORF HOS2 CAL0004384 PMID: 20730094|CGD_REF: CAL0126184 homozygous diploid, classical genetics null hos2/hos2 (Tn7::UAU1 disruption) BWP17 filamentous growth: increased solid M199 pH8, Spider, embedded agar and serum media, but not on SLAD medium; liquid Spider, GlcNac and serum media C. albicans orf19.5377 ORF HOS2 CAL0004384 PMID: 20730094|CGD_REF: CAL0126184 homozygous diploid, classical genetics null hos2/hos2 (Tn7::UAU1 disruption) BWP17 invasive growth: increased embedded conditions C. albicans orf19.5377 ORF HOS2 CAL0004384 PMID: 20485517|CGD_REF: CAL0125674 homozygous diploid, classical genetics null SN152 filamentous growth: abnormal MTL a/a opaque cells, Lee's agar plates wrinkled colonies composed of mostly pseudohyphal structures C. albicans orf19.5377 ORF HOS2 CAL0004384 PMID: 20485517|CGD_REF: CAL0125674 homozygous diploid, classical genetics null SN152 colony appearance: abnormal MTL a/a opaque cells, Lee's agar plates wrinkled colonies composed of mostly pseudohyphal structures C. albicans orf19.5377 ORF HOS2 CAL0004384 PMID: 20485517|CGD_REF: CAL0125674 homozygous diploid, classical genetics null SN152 filamentous growth: increased MTL a/alpha cells, YPD medium, elevated temperature wrinkled colonies composed of mostly true hyphae C. albicans orf19.5378 ORF SCL1 CAL0004386 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.5378 ORF SCL1 CAL0004386 PMID: 21135205|CGD_REF: CAL0139967 heterozygous diploid, large-scale survey (large-scale identification of genes essential for virulence in mouse) repressible CAI-4 virulence: absent mouse intravenous infection C. albicans orf19.5379 ORF ERG4 CAL0004388 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.5379 ORF ERG4 CAL0004388 PMID: 21135205|CGD_REF: CAL0139967 heterozygous diploid, competitive growth (large-scale identification of genes essential for virulence in mouse) repressible CAI-4 virulence: decreased mouse intravenous infection C. albicans orf19.538 ORF GPI2 CAL0000171 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.538 ORF GPI2 CAL0000171 PMID: 24356967|CGD_REF: CAL0000173720 homozygous diploid, classical genetics null CAI-4 inviable C. albicans orf19.538 ORF GPI2 CAL0000171 PMID: 24356967|CGD_REF: CAL0000173720 heterozygous diploid, classical genetics null CAI-4 resistance to chemicals: decreased Congo Red C. albicans orf19.538 ORF GPI2 CAL0000171 PMID: 24356967|CGD_REF: CAL0000173720 heterozygous diploid, classical genetics null CAI-4 resistance to chemicals: decreased Calcofluor White C. albicans orf19.538 ORF GPI2 CAL0000171 PMID: 24356967|CGD_REF: CAL0000173720 heterozygous diploid, classical genetics null CAI-4 resistance to chemicals: decreased sodium dodecyl sulfate C. albicans orf19.538 ORF GPI2 CAL0000171 PMID: 24356967|CGD_REF: CAL0000173720 heterozygous diploid, classical genetics null CAI-4 resistance to chemicals: increased azole C. albicans orf19.538 ORF GPI2 CAL0000171 PMID: 24356967|CGD_REF: CAL0000173720 heterozygous diploid, classical genetics null CAI-4 resistance to chemicals: decreased terbinafine C. albicans orf19.538 ORF GPI2 CAL0000171 PMID: 24356967|CGD_REF: CAL0000173720 heterozygous diploid, classical genetics null CAI-4 filamentous growth: decreased C. albicans orf19.5380 ORF LYS144 CAL0004397 PMID: 15964282|CGD_REF: CAL0114274 homozygous diploid, systematic mutation set (split-marker transposon insertion strategy to disrupt both alleles) null BWP17 viable C. albicans orf19.5380 ORF LYS144 CAL0004397 PMID: 15964282|CGD_REF: CAL0114274 homozygous diploid, systematic mutation set (split-marker transposon insertion strategy to disrupt both alleles) null BWP17 biofilm formation: normal C. albicans orf19.5380 ORF LYS144 CAL0004397 PMID: 23526879|CGD_REF: CAL0000158852 homozygous diploid, classical genetics null SN152 viable C. albicans orf19.5380 ORF LYS144 CAL0004397 PMID: 23526879|CGD_REF: CAL0000158852 homozygous diploid, classical genetics null SN152 virulence: decreased significant defect in GI tract colonization mouse gastrointestinal tract infection C. albicans orf19.5381 ORF CAL0004399 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.5383 ORF PMA1 CAL0004402 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.5383 ORF PMA1 CAL0004402 PMID: 2149266|CGD_REF: CAL0092087 unknown ploidy, classical genetics unspecified Other C. albicans resistance to chemicals: increased sodium orthovanadate C. albicans orf19.5383 ORF PMA1 CAL0004402 PMID: 21135205|CGD_REF: CAL0139967 heterozygous diploid, large-scale survey (large-scale identification of genes essential for virulence in mouse) repressible CAI-4 virulence: absent mouse intravenous infection C. albicans orf19.5384 ORF CHS8 CAL0004405 PMID: 14516767|CGD_REF: CAL0081014 homozygous diploid, classical genetics null Not recorded germ tube formation: normal wild-type germ tube morphology C. albicans orf19.5384 ORF CHS8 CAL0004405 PMID: 14516767|CGD_REF: CAL0081014 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased Calcofluor White effect is slight C. albicans orf19.5384 ORF CHS8 CAL0004405 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.5384 ORF CHS8 CAL0004405 PMID: 14516767|CGD_REF: CAL0081014 homozygous diploid, classical genetics null Not recorded viable wild-type growth rate C. albicans orf19.5384 ORF CHS8 CAL0004405 PMID: 14516767|CGD_REF: CAL0081014 homozygous diploid, classical genetics null Not recorded cellular morphology: normal C. albicans orf19.5384 ORF CHS8 CAL0004405 PMID: 14516767|CGD_REF: CAL0081014 homozygous diploid, classical genetics null Not recorded chitin deposition: normal in yeast-form cells and hyphae C. albicans orf19.5384 ORF CHS8 CAL0004405 PMID: 17971081|CGD_REF: CAL0118713 homozygous diploid, classical genetics null Not recorded chitin deposition: abnormal long-chitin microfibrils are absent C. albicans orf19.5389 ORF FKH2 CAL0004415 PMID: 12455696|CGD_REF: CAL0080790 homozygous diploid, classical genetics null Not recorded flocculation: increased C. albicans orf19.5389 ORF FKH2 CAL0004415 PMID: 12455696|CGD_REF: CAL0080790 homozygous diploid, classical genetics null Not recorded vegetative growth: decreased rate C. albicans orf19.5389 ORF FKH2 CAL0004415 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.5389 ORF FKH2 CAL0004415 PMID: 12455696|CGD_REF: CAL0080790 heterozygous diploid, classical genetics null Not recorded viable C. albicans orf19.5389 ORF FKH2 CAL0004415 PMID: 12455696|CGD_REF: CAL0080790 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.5389 ORF FKH2 CAL0004415 PMID: 12455696|CGD_REF: CAL0080790 homozygous diploid, classical genetics null BWP17 hyphal growth: absent growth is pseudohyphal under all conditions tested C. albicans orf19.5389 ORF FKH2 CAL0004415 PMID: 12455696|CGD_REF: CAL0080790 heterozygous diploid, classical genetics null Not recorded cellular morphology: normal C. albicans orf19.5389 ORF FKH2 CAL0004415 PMID: 12455696|CGD_REF: CAL0080790 homozygous diploid, classical genetics null Not recorded cytokinesis: absent C. albicans orf19.5389 ORF FKH2 CAL0004415 PMID: 12455696|CGD_REF: CAL0080790 homozygous diploid, classical genetics null Not recorded pseudohyphal growth: increased pseudohyphal growth is constitutive C. albicans orf19.5389 ORF FKH2 CAL0004415 PMID: 23856128|CGD_REF: CAL0000172540 homozygous diploid, classical genetics null BWP17 resistance to chemicals: decreased propolis C. albicans orf19.5389 ORF FKH2 CAL0004415 PMID: 12455696|CGD_REF: CAL0080790 homozygous diploid, classical genetics null Not recorded virulence: decreased human vascular endothelial cells and oral epithelial cells in vitro model of infection C. albicans orf19.5391 ORF CAL0004426 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.5392 ORF NGT1 CAL0004428 PMID: 17192409|CGD_REF: CAL0117211 homozygous diploid, classical genetics null BWP17 germ tube formation: decreased GlcNAc-containing medium defect is overcome at high GlcNAc concentration C. albicans orf19.5392 ORF NGT1 CAL0004428 PMID: 17192409|CGD_REF: CAL0117211 heterozygous diploid, classical genetics null BWP17 germ tube formation: normal GlcNAc-containing medium C. albicans orf19.5392 ORF NGT1 CAL0004428 PMID: 17192409|CGD_REF: CAL0117211 homozygous diploid, classical genetics null BWP17 germ tube formation: normal serum-containing medium C. albicans orf19.5392 ORF NGT1 CAL0004428 PMID: 17192409|CGD_REF: CAL0117211 homozygous diploid, classical genetics null Not recorded small molecule transport: decreased GlcNAc C. albicans orf19.5392 ORF NGT1 CAL0004428 PMID: 17192409|CGD_REF: CAL0117211 homozygous diploid, classical genetics null Not recorded utilization of carbon source: decreased GlcNAc C. albicans orf19.5392 ORF NGT1 CAL0004428 PMID: 17192409|CGD_REF: CAL0117211 heterozygous diploid, classical genetics null Not recorded utilization of carbon source: normal GlcNAc C. albicans orf19.5392 ORF NGT1 CAL0004428 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.5392 ORF NGT1 CAL0004428 PMID: 17192409|CGD_REF: CAL0117211 heterozygous diploid, classical genetics null Not recorded viable C. albicans orf19.5392 ORF NGT1 CAL0004428 PMID: 17192409|CGD_REF: CAL0117211 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.5393 ORF CAL0004430 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.5393 ORF CAL0004430 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.5393 ORF CAL0004430 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: decreased rate liquid synthetic complete medium C. albicans orf19.5393 ORF CAL0004430 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.5393 ORF CAL0004430 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.5399 ORF IFF11 CAL0004442 PMID: 17371861|CGD_REF: CAL0117880 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased Calcofluor White C. albicans orf19.5399 ORF IFF11 CAL0004442 PMID: 17371861|CGD_REF: CAL0117880 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased sodium dodecyl sulfate C. albicans orf19.5399 ORF IFF11 CAL0004442 PMID: 17371861|CGD_REF: CAL0117880 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.5399 ORF IFF11 CAL0004442 PMID: 17371861|CGD_REF: CAL0117880 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased Congo Red C. albicans orf19.5399 ORF IFF11 CAL0004442 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.5399 ORF IFF11 CAL0004442 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.5399 ORF IFF11 CAL0004442 PMID: 17371861|CGD_REF: CAL0117880 homozygous diploid, classical genetics null Not recorded virulence: decreased mouse intravenous infection C. albicans orf19.5399 ORF IFF11 CAL0004442 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.5399 ORF IFF11 CAL0004442 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.54 ORF RHD1 CAL0000604 PMID: 18234669|CGD_REF: CAL0119018 homozygous diploid, classical genetics null Not recorded resistance to chemicals: normal Calcofluor White C. albicans orf19.54 ORF RHD1 CAL0000604 PMID: 18234669|CGD_REF: CAL0119018 homozygous diploid, classical genetics null Not recorded resistance to chemicals: normal sodium dodecyl sulfate C. albicans orf19.54 ORF RHD1 CAL0000604 PMID: 18234669|CGD_REF: CAL0119018 homozygous diploid, classical genetics null Not recorded viable rich medium wild-type growth rate C. albicans orf19.54 ORF RHD1 CAL0000604 PMID: 18234669|CGD_REF: CAL0119018 homozygous diploid, classical genetics null BWP17 hyphal growth: normal serum-containing medium C. albicans orf19.54 ORF RHD1 CAL0000604 PMID: 18234669|CGD_REF: CAL0119018 homozygous diploid, classical genetics null Not recorded cell wall morphology: abnormal strongly decreased beta-mannosylation of both acid-stable and acid-labile fractions of phosphopeptidomannan C. albicans orf19.54 ORF RHD1 CAL0000604 PMID: 18234669|CGD_REF: CAL0119018 homozygous diploid, classical genetics null Not recorded chlamydospore formation: normal RAT medium C. albicans orf19.54 ORF RHD1 CAL0000604 PMID: 18234669|CGD_REF: CAL0119018 homozygous diploid, classical genetics null Not recorded ionic stress resistance: normal sodium chloride C. albicans orf19.54 ORF RHD1 CAL0000604 PMID: 18234669|CGD_REF: CAL0119018 homozygous diploid, classical genetics null Not recorded resistance to chemicals: normal calcium dichloride C. albicans orf19.540 ORF CAL0000194 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.540 ORF CAL0000194 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.540 ORF CAL0000194 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.540 ORF CAL0000194 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.540 ORF CAL0000194 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.5404.1 ORF FLO9 CAL0000142932 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.5404.1 ORF FLO9 CAL0000142932 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.5404.1 ORF FLO9 CAL0000142932 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.5404.1 ORF FLO9 CAL0000142932 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.5404.1 ORF FLO9 CAL0000142932 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, competitive growth (haploinsufficient phenotype assay, barcode deletion set) null SC5314 resistance to chemicals: decreased ergosterol analogs (ECC69 and/or ECC1384) C. albicans orf19.5404.1 ORF FLO9 CAL0000142932 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.5406 ORF CAL0005162 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.5406 ORF CAL0005162 PMID: 19779551|CGD_REF: CAL0124331 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.5406 ORF CAL0005162 PMID: 19779551|CGD_REF: CAL0124331 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.5406 ORF CAL0005162 PMID: 19779551|CGD_REF: CAL0124331 homozygous diploid, classical genetics null Not recorded colony appearance: abnormal solid Spider medium C. albicans orf19.5406 ORF CAL0005162 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.5406 ORF CAL0005162 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: abnormal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.5406 ORF CAL0005162 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.5406 ORF CAL0005162 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.5406 ORF CAL0005162 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 invasive growth: decreased solid SLAD media C. albicans orf19.5407 ORF SOF1 CAL0005164 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.5408 ORF HRK1 CAL0005166 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.541 ORF CAL0000196 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.5410 ORF CAL0005179 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.5411 ORF CAL0005180 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.5412 ORF CAL0005181 PMID: 17873081|CGD_REF: CAL0118685 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.5412 ORF CAL0005181 PMID: 17873081|CGD_REF: CAL0118685 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased caspofungin C. albicans orf19.5412 ORF CAL0005181 PMID: 17873081|CGD_REF: CAL0118685 homozygous diploid, classical genetics null BWP17 biofilm formation: abnormal C. albicans orf19.5412 ORF CAL0005181 PMID: 23856128|CGD_REF: CAL0000172540 homozygous diploid, classical genetics null BWP17 resistance to chemicals: decreased propolis C. albicans orf19.5413 ORF CAL0005182 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.5416 ORF ESA1 CAL0005186 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.5416 ORF ESA1 CAL0005186 PMID: 23355007|CGD_REF: CAL0000158487 homozygous diploid, classical genetics null BWP17 viable C. albicans orf19.5416 ORF ESA1 CAL0005186 PMID: 23355007|CGD_REF: CAL0000158487 homozygous diploid, classical genetics null BWP17 cold sensitivity: decreased C. albicans orf19.5416 ORF ESA1 CAL0005186 PMID: 23355007|CGD_REF: CAL0000158487 homozygous diploid, classical genetics null BWP17 heat sensitivity: increased C. albicans orf19.5416 ORF ESA1 CAL0005186 PMID: 23355007|CGD_REF: CAL0000158487 homozygous diploid, classical genetics null BWP17 filamentous growth: absent C. albicans orf19.5416 ORF ESA1 CAL0005186 PMID: 23355007|CGD_REF: CAL0000158487 homozygous diploid, classical genetics null BWP17 resistance to chemicals: decreased hydroxyurea C. albicans orf19.5416 ORF ESA1 CAL0005186 PMID: 23355007|CGD_REF: CAL0000158487 homozygous diploid, classical genetics null BWP17 resistance to chemicals: decreased methyl methanesulfonate C. albicans orf19.5416 ORF ESA1 CAL0005186 PMID: 23355007|CGD_REF: CAL0000158487 homozygous diploid, classical genetics null BWP17 resistance to chemicals: decreased camptothecin C. albicans orf19.5416 ORF ESA1 CAL0005186 PMID: 23355007|CGD_REF: CAL0000158487 homozygous diploid, classical genetics null BWP17 oxidative stress resistance: decreased hydrogen peroxide C. albicans orf19.5416 ORF ESA1 CAL0005186 PMID: 23355007|CGD_REF: CAL0000158487 homozygous diploid, classical genetics null BWP17 resistance to chemicals: increased Congo Red C. albicans orf19.5416 ORF ESA1 CAL0005186 PMID: 23355007|CGD_REF: CAL0000158487 homozygous diploid, classical genetics null BWP17 resistance to chemicals: increased caspofungin C. albicans orf19.5418 ORF CAL0005190 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.5420 ORF CAL0005205 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.5422 ORF CAL0005206 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 invasive growth: decreased solid SLAD media C. albicans orf19.5423 ORF EST3 CAL0005207 PMID: 19172753|CGD_REF: CAL0122282 homozygous diploid, classical genetics unspecified Not recorded telomere length: normal D59A, R72A or S92A alleles; integrated in homozygous null mutant background C. albicans orf19.5423 ORF EST3 CAL0005207 PMID: 19172753|CGD_REF: CAL0122282 homozygous diploid, classical genetics unspecified Not recorded telomere length: decreased D91A or DS91AA allele has null mutant phenotype and defects in TER1 RNA interaction and association of Est1p with holoenzyme; integrated in homozygous null mutant background C. albicans orf19.5423 ORF EST3 CAL0005207 PMID: 12477797|CGD_REF: CAL0081268 homozygous diploid, classical genetics null Not recorded telomere length: decreased C. albicans orf19.5423 ORF EST3 CAL0005207 PMID: 16714448|CGD_REF: CAL0116045 homozygous diploid, classical genetics null Not recorded telomere length: decreased C. albicans orf19.5423 ORF EST3 CAL0005207 PMID: 17545315|CGD_REF: CAL0118239 homozygous diploid, classical genetics null Not recorded telomere length: decreased C. albicans orf19.5423 ORF EST3 CAL0005207 PMID: 12477797|CGD_REF: CAL0081268 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.5423 ORF EST3 CAL0005207 PMID: 16714448|CGD_REF: CAL0116045 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.5423 ORF EST3 CAL0005207 PMID: 17545315|CGD_REF: CAL0118239 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.5425 ORF CAL0005210 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.5426 ORF CAL0005212 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.543 ORF FUM11 CAL0000200 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.5432 ORF TPT1 CAL0005230 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.5432 ORF TPT1 CAL0005230 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient YNB medium C. albicans orf19.5432 ORF TPT1 CAL0005230 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient SLAD medium C. albicans orf19.5436 ORF UTP8 CAL0005235 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.5437 ORF RHR2 CAL0005236 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.5437 ORF RHR2 CAL0005236 PMID: 15796987|CGD_REF: CAL0104027 heterozygous diploid, classical genetics null Not recorded viable C. albicans orf19.5437 ORF RHR2 CAL0005236 PMID: 15796987|CGD_REF: CAL0104027 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.5437 ORF RHR2 CAL0005236 PMID: 15796987|CGD_REF: CAL0104027 homozygous diploid, classical genetics null Not recorded ionic stress resistance: decreased sodium chloride defect in salt stress-induced glycerol accumulation C. albicans orf19.5437 ORF RHR2 CAL0005236 PMID: 15796987|CGD_REF: CAL0104027 heterozygous diploid, classical genetics null Not recorded ionic stress resistance: normal sodium chloride C. albicans orf19.5437 ORF RHR2 CAL0005236 PMID: 21414038|CGD_REF: CAL0141808 homozygous diploid, classical genetics null BWP17 viable C. albicans orf19.5437 ORF RHR2 CAL0005236 PMID: 21407800|CGD_REF: CAL0141800 homozygous diploid, large-scale survey null BWP17 interaction with host/environment: abnormal significantly reduced damage to epithelial cells, but normal adhesion and invasion ex vivo model of infection C. albicans orf19.5437 ORF RHR2 CAL0005236 PMID: 23572557|CGD_REF: CAL0000158900 homozygous diploid, classical genetics null rhr2::Tn7-UAU1/rhr2::Tn7-URA3 BWP17 biofilm formation: decreased Spider medium, 48 hr biofilm consists primarily of a basal layer of yeast-form cells with few interspersed hyphae; defect rescued by Spider-glycerol medium, in which glycerol replaces mannitol as the carbon source C. albicans orf19.5437 ORF RHR2 CAL0005236 PMID: 23572557|CGD_REF: CAL0000158900 homozygous diploid, classical genetics null rhr2::Tn7-UAU1/rhr2::Tn7-URA3 BWP17 RNA accumulation: decreased ALS3 C. albicans orf19.5437 ORF RHR2 CAL0005236 PMID: 23572557|CGD_REF: CAL0000158900 homozygous diploid, classical genetics null rhr2::Tn7-UAU1/rhr2::Tn7-URA3 BWP17 RNA accumulation: decreased HWP1 C. albicans orf19.5437 ORF RHR2 CAL0005236 PMID: 23572557|CGD_REF: CAL0000158900 homozygous diploid, classical genetics null rhr2::Tn7-UAU1/rhr2::Tn7-URA3 BWP17 chemical compound accumulation: decreased biofilm glycerol Spider medium, 48 hr mutant had a aprox. 50% reduction in biofilm glycerol accumulation compared to the wild type C. albicans orf19.5437 ORF RHR2 CAL0005236 PMID: 23572557|CGD_REF: CAL0000158900 homozygous diploid, classical genetics null rhr2::Tn7-UAU1/rhr2::Tn7-URA3 BWP17 RNA accumulation: decreased ALS1 C. albicans orf19.5437 ORF RHR2 CAL0005236 PMID: 23572557|CGD_REF: CAL0000158900 homozygous diploid, classical genetics null rhr2::Tn7-UAU1/rhr2::Tn7-URA3 BWP17 adhesion: decreased decreased adherence to an abiotic silicone substrate other model C. albicans orf19.5437 ORF RHR2 CAL0005236 PMID: 23572557|CGD_REF: CAL0000158900 homozygous diploid, classical genetics null BWP17 resistance to chemicals: decreased fluconazole RPMI+MOPS+Histidine medium , 6 hours without shaking at 37 degrees C 24 hr fluconazole treatment in 96 well plates C. albicans orf19.544 ORF RPR2 CAL0000202 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.544.1 ORF PRE6 CAF0006901 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.5440 ORF RPT2 CAL0005257 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.5443 ORF BNA4 CAL0005260 PMID: 12773383|CGD_REF: CAL0087974 heterozygous diploid, classical genetics (haploinsufficient phenotype assay) null CAI-4 viable heterozygous transposon insertion C. albicans orf19.5443 ORF BNA4 CAL0005260 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.5443 ORF BNA4 CAL0005260 PMID: 12773383|CGD_REF: CAL0087974 heterozygous diploid, classical genetics (haploinsufficient phenotype assay) null CAI-4 filamentous growth: decreased solid Spider medium heterozygous transposon insertion C. albicans orf19.5443 ORF BNA4 CAL0005260 PMID: 22438810|CGD_REF: CAL0000156986 homozygous diploid, classical genetics null BWP17 viable C. albicans orf19.5443 ORF BNA4 CAL0005260 PMID: 22438810|CGD_REF: CAL0000156986 homozygous diploid, classical genetics null BWP17 virulence: decreased mutants have reduced capacity to damage oral epithelial cells in vitro model of infection (monolayers of oral epithelial cells) C. albicans orf19.5444 ORF TIM44 CAL0005261 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.5444 ORF TIM44 CAL0005261 PMID: 21135205|CGD_REF: CAL0139967 heterozygous diploid, large-scale survey (large-scale identification of genes essential for virulence in mouse) repressible CAI-4 virulence: absent mouse intravenous infection C. albicans orf19.5445 ORF GLO3 CAL0005263 PMID: 14663094|CGD_REF: CAL0080633 homozygous diploid, systematic mutation set (homozygous insertion mutants generated with URA3-ARG4-URA3 (UAU1) cassette) null BWP17 viable C. albicans orf19.5445 ORF GLO3 CAL0005263 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: decreased growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.5445 ORF GLO3 CAL0005263 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: abnormal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.5445 ORF GLO3 CAL0005263 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.5445 ORF GLO3 CAL0005263 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.5447 ORF HGT19 CAL0005265 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.5449 ORF CAL0005268 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.5449 ORF CAL0005268 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.5449 ORF CAL0005268 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.5449 ORF CAL0005268 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.5450 ORF ETR1 CAL0005272 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.5455 ORF CAL0005276 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.5459 ORF CAL0005282 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.5463 ORF SEC6 CAL0005292 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.5463 ORF SEC6 CAL0005292 PMID: 21135205|CGD_REF: CAL0139967 heterozygous diploid, large-scale survey (large-scale identification of genes essential for virulence in mouse) repressible CAI-4 virulence: absent mouse intravenous infection C. albicans orf19.5465 ORF CAL0005297 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.547 ORF CAL0000208 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.5479 ORF FGR12 CAL0005326 PMID: 12773383|CGD_REF: CAL0087974 heterozygous diploid, classical genetics (haploinsufficient phenotype assay) null CAI-4 viable heterozygous transposon insertion C. albicans orf19.5479 ORF FGR12 CAL0005326 PMID: 12773383|CGD_REF: CAL0087974 heterozygous diploid, classical genetics (haploinsufficient phenotype assay) null CAI-4 filamentous growth: decreased solid Spider medium or solid YEPD plus serum heterozygous transposon insertion C. albicans orf19.548 ORF CDC10 CAL0000214 PMID: 12181342|CGD_REF: CAL0080842 homozygous diploid, classical genetics null Not recorded septum formation: abnormal abolition of septin ring C. albicans orf19.548 ORF CDC10 CAL0000214 PMID: 16858141|CGD_REF: CAL0116320 heterozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased Calcofluor White defect is rescued by 1M sorbitol C. albicans orf19.548 ORF CDC10 CAL0000214 PMID: 16858141|CGD_REF: CAL0116320 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased Calcofluor White defect is rescued by 1M sorbitol C. albicans orf19.548 ORF CDC10 CAL0000214 PMID: 12181342|CGD_REF: CAL0080842 homozygous diploid, classical genetics null Not recorded heat sensitivity: increased C. albicans orf19.548 ORF CDC10 CAL0000214 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.548 ORF CDC10 CAL0000214 PMID: 12181342|CGD_REF: CAL0080842 homozygous diploid, classical genetics null Not recorded viable wild-type growth rate C. albicans orf19.548 ORF CDC10 CAL0000214 PMID: 12819094|CGD_REF: CAL0080843 homozygous diploid, classical genetics null Not recorded viable wild-type growth rate C. albicans orf19.548 ORF CDC10 CAL0000214 PMID: 12819094|CGD_REF: CAL0080843 heterozygous diploid, classical genetics null Not recorded viable C. albicans orf19.548 ORF CDC10 CAL0000214 PMID: 16858141|CGD_REF: CAL0116320 heterozygous diploid, classical genetics null Not recorded viable C. albicans orf19.548 ORF CDC10 CAL0000214 PMID: 16858141|CGD_REF: CAL0116320 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.548 ORF CDC10 CAL0000214 PMID: 16858141|CGD_REF: CAL0116320 homozygous diploid, classical genetics null Not recorded protein/peptide distribution: abnormal Int1p localization to bud neck is decreased Int1p C. albicans orf19.548 ORF CDC10 CAL0000214 PMID: 16858141|CGD_REF: CAL0116320 heterozygous diploid, classical genetics null Not recorded adhesion: decreased adhesion to human epithelial (HeLa) cells phenotype is intermediate between that of wild type and the homozygous null mutant C. albicans orf19.548 ORF CDC10 CAL0000214 PMID: 16858141|CGD_REF: CAL0116320 homozygous diploid, classical genetics null Not recorded adhesion: decreased adhesion to human epithelial (HeLa) cells C. albicans orf19.548 ORF CDC10 CAL0000214 PMID: 12819094|CGD_REF: CAL0080843 homozygous diploid, classical genetics null BWP17 hyphal growth: normal within macrophages C. albicans orf19.548 ORF CDC10 CAL0000214 PMID: 12181342|CGD_REF: CAL0080842 homozygous diploid, classical genetics null BWP17 invasive growth: normal C. albicans orf19.548 ORF CDC10 CAL0000214 PMID: 12819094|CGD_REF: CAL0080843 homozygous diploid, classical genetics null BWP17 invasive growth: decreased solid serum-containing medium C. albicans orf19.548 ORF CDC10 CAL0000214 PMID: 16858141|CGD_REF: CAL0116320 homozygous diploid, classical genetics null Not recorded cell wall morphology: abnormal defect is enhanced at elevated temperature C. albicans orf19.548 ORF CDC10 CAL0000214 PMID: 16858141|CGD_REF: CAL0116320 heterozygous diploid, classical genetics null Not recorded cell wall morphology: abnormal defect is intermediate between that of the homozygous null mutant and wild type; defect is enhanced at elevated temperature C. albicans orf19.548 ORF CDC10 CAL0000214 PMID: 12819094|CGD_REF: CAL0080843 homozygous diploid, classical genetics null Not recorded chitin deposition: abnormal C. albicans orf19.548 ORF CDC10 CAL0000214 PMID: 16002645|CGD_REF: CAL0114398 homozygous diploid, classical genetics null Not recorded chlamydospore formation: abnormal abnormal chlamydospore morphology: septum is lacking at suspensor cell-chlamydospore junction; ectopic chitin deposition in chlamydospores; some multinucleate chlamydospores and suspensor cells C. albicans orf19.548 ORF CDC10 CAL0000214 PMID: 12181342|CGD_REF: CAL0080842 homozygous diploid, classical genetics null Not recorded cytokinesis: decreased C. albicans orf19.548 ORF CDC10 CAL0000214 PMID: 16002645|CGD_REF: CAL0114398 homozygous diploid, classical genetics null CAI-4 filamentous growth: abnormal curved, kinked filaments C. albicans orf19.548 ORF CDC10 CAL0000214 PMID: 16858141|CGD_REF: CAL0116320 heterozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased Congo Red defect is rescued by 1M sorbitol C. albicans orf19.548 ORF CDC10 CAL0000214 PMID: 16858141|CGD_REF: CAL0116320 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased Congo Red defect is rescued by 1M sorbitol C. albicans orf19.548 ORF CDC10 CAL0000214 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: decreased growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.548 ORF CDC10 CAL0000214 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.548 ORF CDC10 CAL0000214 PMID: 23856128|CGD_REF: CAL0000172540 homozygous diploid, classical genetics null BWP17 resistance to chemicals: decreased propolis C. albicans orf19.548 ORF CDC10 CAL0000214 PMID: 12819094|CGD_REF: CAL0080843 homozygous diploid, classical genetics null Not recorded virulence: decreased exhibits decreased kidney invasion mouse intravenous infection C. albicans orf19.548 ORF CDC10 CAL0000214 PMID: 16858141|CGD_REF: CAL0116320 homozygous diploid, classical genetics null Not recorded virulence: absent exhibits decreased organ colonization mouse intravenous infection C. albicans orf19.548 ORF CDC10 CAL0000214 PMID: 16858141|CGD_REF: CAL0116320 heterozygous diploid, classical genetics null Not recorded virulence: decreased exhibits decreased organ colonization mouse intravenous infection C. albicans orf19.548 ORF CDC10 CAL0000214 PMID: 12819094|CGD_REF: CAL0080843 homozygous diploid, classical genetics null Not recorded virulence: decreased mouse intravenous infection C. albicans orf19.548 ORF CDC10 CAL0000214 PMID: 12819094|CGD_REF: CAL0080843 heterozygous diploid, classical genetics null Not recorded virulence: normal mouse intravenous infection C. albicans orf19.548 ORF CDC10 CAL0000214 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.548 ORF CDC10 CAL0000214 PMID: 20140194|CGD_REF: CAL0124995 homozygous diploid, classical genetics null Other C. albicans resistance to chemicals: decreased caspofungin C. albicans orf19.548 ORF CDC10 CAL0000214 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.5480 ORF ILV1 CAL0005334 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.5480 ORF ILV1 CAL0005334 PMID: 20019084|CGD_REF: CAL0124886 homozygous diploid, classical genetics null ilv1::SAT1/ilv1::FRT SC5314 viable C. albicans orf19.5480 ORF ILV1 CAL0005334 PMID: 20019084|CGD_REF: CAL0124886 homozygous diploid, classical genetics null ilv1::SAT1/ilv1::FRT SC5314 virulence: decreased mouse intravenous infection C. albicans orf19.5480 ORF ILV1 CAL0005334 PMID: 20019084|CGD_REF: CAL0124886 homozygous diploid, classical genetics null ilv1::SAT1/ilv1::FRT SC5314 starvation resistance: decreased mutant cells lose viability upon isoleucine and valine starvation C. albicans orf19.5483 ORF CAL0005338 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.5484 ORF SER1 CAL0005340 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.5485 ORF MEC3 CAL0005342 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.5485 ORF MEC3 CAL0005342 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.5485 ORF MEC3 CAL0005342 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.5485 ORF MEC3 CAL0005342 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.5486 ORF CAL0005344 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.5486 ORF CAL0005344 PMID: 19623926|CGD_REF: CAL0124054 heterozygous diploid, competitive growth (haploinsufficient phenotype assay, barcode deletion set) null SC5314 resistance to chemicals: decreased cordycepin C. albicans orf19.5486 ORF CAL0005344 PMID: 19623926|CGD_REF: CAL0124054 heterozygous diploid, competitive growth (haploinsufficient phenotype assay, barcode deletion set) null SC5314 resistance to chemicals: decreased parnafungin C. albicans orf19.5486 ORF CAL0005344 PMID: 21135205|CGD_REF: CAL0139967 heterozygous diploid, large-scale survey (large-scale identification of genes essential for virulence in mouse) repressible CAI-4 virulence: absent mouse intravenous infection C. albicans orf19.5487 ORF CDC46 CAL0005346 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.5492 ORF CAL0005358 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.5493 ORF GSP1 CAL0005360 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.5493 ORF GSP1 CAL0005360 PMID: 10854789|CGD_REF: CAL0081361 homozygous diploid, classical genetics null gsp1::hisG/gsp1::hisG?URA3?hisG CAI-4 inviable homozygous null mutant strain could not be recovered, suggesting that the gene is essential under the selection conditions C. albicans orf19.5493 ORF GSP1 CAL0005360 PMID: 10854789|CGD_REF: CAL0081361 heterozygous diploid, classical genetics null gsp1::hisG?URA3?hisG/GSP1 CAI-4 chromosome/plasmid maintenance: abnormal C. albicans orf19.5493 ORF GSP1 CAL0005360 PMID: 10854789|CGD_REF: CAL0081361 heterozygous diploid, classical genetics null gsp1::hisG?URA3?hisG/GSP1 CAI-4 viable C. albicans orf19.5493 ORF GSP1 CAL0005360 PMID: 14507372|CGD_REF: CAL0088818 heterozygous diploid, large-scale survey (large-scale identification of essential genes by gene replacement and conditional expression (GRACE) method) repressible CAI-4 inviable one allele is deleted and the other is placed under repressible Tet promoter C. albicans orf19.5495 ORF CAL0005365 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.5495 ORF CAL0005365 PMID: 14663094|CGD_REF: CAL0080633 homozygous diploid, systematic mutation set (homozygous insertion mutants generated with URA3-ARG4-URA3 (UAU1) cassette) null BWP17 viable C. albicans orf19.5496 ORF AVT1 CAL0005367 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.5498 ORF EFH1 CAL0005369 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.5498 ORF EFH1 CAL0005369 PMID: 15218092|CGD_REF: CAL0081199 homozygous diploid, classical genetics null Not recorded viable no apparent phenotype C. albicans orf19.5498 ORF EFH1 CAL0005369 PMID: 15218092|CGD_REF: CAL0081199 heterozygous diploid, classical genetics null Not recorded viable C. albicans orf19.5498 ORF EFH1 CAL0005369 PMID: 15218092|CGD_REF: CAL0081199 heterozygous diploid, classical genetics overexpression Not recorded phenotypic switching: increased opaque-to-white switching C. albicans orf19.5498 ORF EFH1 CAL0005369 PMID: 15218092|CGD_REF: CAL0081199 heterozygous diploid, classical genetics overexpression Not recorded pseudohyphal growth: increased increased pseudohyphal growth, with defect in hyphal induction C. albicans orf19.5498 ORF EFH1 CAL0005369 PMID: 18069889|CGD_REF: CAL0118787 heterozygous diploid, classical genetics overexpression Not recorded virulence: decreased decreased colonization of mouse intestinal tract mouse gastrointestinal tract infection C. albicans orf19.5498 ORF EFH1 CAL0005369 PMID: 18069889|CGD_REF: CAL0118787 homozygous diploid, classical genetics null Not recorded virulence: increased increased colonization of mouse intestinal tract mouse gastrointestinal tract infection C. albicans orf19.5499 ORF CAL0005370 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.5499 ORF CAL0005370 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: decreased growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.5499 ORF CAL0005370 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.5499 ORF CAL0005370 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.5499 ORF CAL0005370 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.55 ORF CAL0000605 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.550 ORF PDX3 CAL0000228 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.5505 ORF HIS7 CAL0006063 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.5505 ORF HIS7 CAL0006063 PMID: 21135205|CGD_REF: CAL0139967 heterozygous diploid, competitive growth (large-scale identification of genes essential for virulence in mouse) repressible CAI-4 virulence: normal mouse intravenous infection C. albicans orf19.5506 ORF PLC1 CAL0006065 PMID: 16207920|CGD_REF: CAL0114770 heterozygous diploid, classical genetics null Not recorded respiratory growth: absent unable to utilize nonfermentable carbon sources glycerol or acetate C. albicans orf19.5506 ORF PLC1 CAL0006065 PMID: 16207920|CGD_REF: CAL0114770 heterozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased itraconazole C. albicans orf19.5506 ORF PLC1 CAL0006065 PMID: 16207920|CGD_REF: CAL0114770 heterozygous diploid, classical genetics repressible Not recorded heat sensitivity: increased C. albicans orf19.5506 ORF PLC1 CAL0006065 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.5506 ORF PLC1 CAL0006065 PMID: 16207920|CGD_REF: CAL0114770 heterozygous diploid, classical genetics null Not recorded viable C. albicans orf19.5506 ORF PLC1 CAL0006065 PMID: 16207920|CGD_REF: CAL0114770 heterozygous diploid, classical genetics repressible Not recorded viable C. albicans orf19.5506 ORF PLC1 CAL0006065 PMID: 16207920|CGD_REF: CAL0114770 heterozygous diploid, classical genetics null CAI-4 hyphal growth: decreased blood agar, serum agar or solid Spider medium at 37 deg C C. albicans orf19.5506 ORF PLC1 CAL0006065 PMID: 16207920|CGD_REF: CAL0114770 heterozygous diploid, classical genetics null Not recorded oxidative stress resistance: decreased hydrogen peroxide C. albicans orf19.5506 ORF PLC1 CAL0006065 PMID: 16207920|CGD_REF: CAL0114770 heterozygous diploid, classical genetics repressible Not recorded cold sensitivity: increased C. albicans orf19.5506 ORF PLC1 CAL0006065 PMID: 16207920|CGD_REF: CAL0114770 homozygous diploid, classical genetics null Not recorded inviable homozygous null mutant strain could not be recovered, suggesting that the gene is essential under the selection conditions C. albicans orf19.5506 ORF PLC1 CAL0006065 PMID: 16207920|CGD_REF: CAL0114770 heterozygous diploid, classical genetics repressible Not recorded osmotic stress resistance: decreased C. albicans orf19.5506 ORF PLC1 CAL0006065 PMID: 16207920|CGD_REF: CAL0114770 heterozygous diploid, classical genetics repressible Not recorded utilization of carbon source: abnormal galactose C. albicans orf19.5506 ORF PLC1 CAL0006065 PMID: 16207920|CGD_REF: CAL0114770 heterozygous diploid, classical genetics repressible Not recorded utilization of nitrogen source: abnormal arginine C. albicans orf19.5506 ORF PLC1 CAL0006065 PMID: 16207920|CGD_REF: CAL0114770 heterozygous diploid, classical genetics null CAI-4 filamentous growth: decreased blood agar at 37 deg C, solid serum-containing medium, solid Spider medium C. albicans orf19.5506 ORF PLC1 CAL0006065 PMID: 16207920|CGD_REF: CAL0114770 heterozygous diploid, classical genetics repressible Not recorded resistance to chemicals: decreased nocodazole C. albicans orf19.5507 ORF ENP1 CAL0006067 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.5507 ORF ENP1 CAL0006067 PMID: 14507372|CGD_REF: CAL0088818 heterozygous diploid, large-scale survey (large-scale identification of essential genes by gene replacement and conditional expression (GRACE) method) repressible CAI-4 viable one allele is deleted and the other is placed under repressible Tet promoter C. albicans orf19.5507 ORF ENP1 CAL0006067 PMID: 12773383|CGD_REF: CAL0087974 heterozygous diploid, classical genetics (haploinsufficient phenotype assay) null CAI-4 filamentous growth: abnormal solid Spider medium or solid YEPD plus serum increased or decreased filamentous growth, depending on the allele and medium; heterozygous transposon insertion C. albicans orf19.551 ORF CAL0000230 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.5513 ORF PRP45 CAL0006088 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.5516 ORF CAL0006093 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.5517 ORF CAL0006095 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.5519 ORF GCV1 CAL0006098 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.552 ORF CAL0000232 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.5521 ORF ISA1 CAL0006111 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.5522 ORF CAL0006112 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 invasive growth: decreased solid SLAD media C. albicans orf19.5524 ORF CAL0006115 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 invasive growth: decreased solid SLAD media C. albicans orf19.5525 ORF CAL0006116 PMID: 21414038|CGD_REF: CAL0141808 homozygous diploid, classical genetics null BWP17 viable C. albicans orf19.5525 ORF CAL0006116 PMID: 21414038|CGD_REF: CAL0141808 homozygous diploid, classical genetics null BWP17 biofilm formation: normal C. albicans orf19.5526 ORF SEC20 CAL0006118 PMID: 11114899|CGD_REF: CAL0081526 heterozygous diploid, classical genetics repressible Not recorded resistance to chemicals: normal vanadate(3-) C. albicans orf19.5526 ORF SEC20 CAL0006118 PMID: 11114899|CGD_REF: CAL0081526 heterozygous diploid, classical genetics repressible Not recorded resistance to chemicals: decreased Calcofluor White C. albicans orf19.5526 ORF SEC20 CAL0006118 PMID: 11114899|CGD_REF: CAL0081526 heterozygous diploid, classical genetics repressible Not recorded resistance to chemicals: decreased neomycin C. albicans orf19.5526 ORF SEC20 CAL0006118 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.5526 ORF SEC20 CAL0006118 PMID: 11114899|CGD_REF: CAL0081526 heterozygous diploid, classical genetics repressible Not recorded hyphal growth: normal serum-containing medium C. albicans orf19.5526 ORF SEC20 CAL0006118 PMID: 14507372|CGD_REF: CAL0088818 heterozygous diploid, large-scale survey (large-scale identification of essential genes by gene replacement and conditional expression (GRACE) method) repressible CAI-4 inviable one allele is deleted and the other is placed under repressible Tet promoter C. albicans orf19.5526 ORF SEC20 CAL0006118 PMID: 11114899|CGD_REF: CAL0081526 homozygous diploid, classical genetics null Not recorded inviable homozygous null mutant strain could not be recovered, suggesting that the gene is essential under the selection conditions C. albicans orf19.5526 ORF SEC20 CAL0006118 PMID: 11114899|CGD_REF: CAL0081526 heterozygous diploid, classical genetics repressible Not recorded endomembrane system morphology: abnormal accumulation of intracellular membranes C. albicans orf19.5526 ORF SEC20 CAL0006118 PMID: 11114899|CGD_REF: CAL0081526 heterozygous diploid, classical genetics repressible Not recorded resistance to chemicals: normal caffeine C. albicans orf19.5526 ORF SEC20 CAL0006118 PMID: 11114899|CGD_REF: CAL0081526 heterozygous diploid, classical genetics repressible Not recorded resistance to chemicals: decreased Hygromycin B C. albicans orf19.5526 ORF SEC20 CAL0006118 PMID: 11114899|CGD_REF: CAL0081526 heterozygous diploid, classical genetics repressible Not recorded resistance to chemicals: decreased nystatin C. albicans orf19.5526 ORF SEC20 CAL0006118 PMID: 11114899|CGD_REF: CAL0081526 heterozygous diploid, classical genetics repressible Not recorded resistance to chemicals: decreased G418 C. albicans orf19.5526 ORF SEC20 CAL0006118 PMID: 11114899|CGD_REF: CAL0081526 heterozygous diploid, classical genetics repressible Not recorded resistance to chemicals: normal clotrimazole C. albicans orf19.5526 ORF SEC20 CAL0006118 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient YPD medium C. albicans orf19.5528 ORF MOB1 CAL0006122 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.5528 ORF MOB1 CAL0006122 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 invasive growth: decreased solid SLAD media C. albicans orf19.553 ORF CAL0000233 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.5530 ORF NAB3 CAL0006136 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.5531 ORF CDC37 CAL0006137 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.5531 ORF CDC37 CAL0006137 PMID: 12524333|CGD_REF: CAL0080691 homozygous diploid, systematic mutation set (homozygous insertion mutants generated with URA3-ARG4-URA3 (UAU1) cassette) null BWP17 inviable homozygous null mutant strain could not be recovered, suggesting that the gene is essential under the selection conditions C. albicans orf19.5531 ORF CDC37 CAL0006137 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, competitive growth (haploinsufficient phenotype assay, barcode deletion set) null SC5314 resistance to chemicals: decreased radicicol C. albicans orf19.5531 ORF CDC37 CAL0006137 PMID: 19115836|CGD_REF: CAL0122036 heterozygous diploid, competitive growth (haploinsufficient phenotype assay, barcode deletion set) null SC5314 resistance to chemicals: decreased radicicol C. albicans orf19.5532 ORF CAL0006138 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.5533 ORF CAL0006139 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.5533 ORF CAL0006139 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient SLAD medium C. albicans orf19.5534 ORF CAL0006141 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.5535 ORF CAL0006143 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.5536 ORF CAL0006145 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.5537 ORF WSC2 CAL0006147 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.5537 ORF WSC2 CAL0006147 PMID: 20384695|CGD_REF: CAL0125373 homozygous diploid, classical genetics null BWP17 viable C. albicans orf19.554 ORF DIT2 CAL0000235 PMID: 18663031|CGD_REF: CAL0119355 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.554 ORF DIT2 CAL0000235 PMID: 18663031|CGD_REF: CAL0119355 homozygous diploid, classical genetics null Not recorded chlamydospore formation: absent C. albicans orf19.554 ORF DIT2 CAL0000235 PMID: 18663031|CGD_REF: CAL0119355 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased caspofungin C. albicans orf19.5542 ORF SAP6 CAL0006162 PMID: 17652724|CGD_REF: CAL0118165 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.5542 ORF SAP6 CAL0006162 PMID: 12427964|CGD_REF: CAL0081850 homozygous diploid, classical genetics null CAI-4 hyphal growth: normal liquid Lee's medium pH 6.5 at 37 deg C C. albicans orf19.5542 ORF SAP6 CAL0006162 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.5542 ORF SAP6 CAL0006162 PMID: 21540243|CGD_REF: CAL0141962 homozygous diploid, classical genetics null Other C. albicans induction of host response: decreased reduced induction of the host antifungal peptide gene Drosomycin insect infection (Drosophila model of gastrointestinal tract infection) C. albicans orf19.5542 ORF SAP6 CAL0006162 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.5542 ORF SAP6 CAL0006162 PMID: 17652724|CGD_REF: CAL0118165 homozygous diploid, classical genetics null Not recorded virulence: decreased mouse corneal infection C. albicans orf19.5542 ORF SAP6 CAL0006162 PMID: 11812212|CGD_REF: CAL0081840 homozygous diploid, classical genetics null Not recorded virulence: normal mouse gastrointestinal tract infection C. albicans orf19.5542 ORF SAP6 CAL0006162 PMID: 9841840|CGD_REF: CAL0081814 homozygous diploid, classical genetics null Not recorded virulence: normal small, transient decrease in colonization observed rat vaginal infection C. albicans orf19.5542 ORF SAP6 CAL0006162 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.5542 ORF SAP6 CAL0006162 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.5543 ORF CAL0006163 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.5544 ORF SAC6 CAL0006165 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.5547 ORF CAL0006170 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.5547 ORF CAL0006170 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.5547 ORF CAL0006170 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.5548 ORF LYS14 CAL0006172 PMID: 15964282|CGD_REF: CAL0114274 homozygous diploid, systematic mutation set (split-marker transposon insertion strategy to disrupt both alleles) null BWP17 viable C. albicans orf19.5548 ORF LYS14 CAL0006172 PMID: 19463063|CGD_REF: CAL0123630 homozygous diploid, systematic mutation set (split-marker transposon insertion strategy to disrupt both alleles) null BWP17 viable C. albicans orf19.5548 ORF LYS14 CAL0006172 PMID: 15964282|CGD_REF: CAL0114274 homozygous diploid, systematic mutation set (split-marker transposon insertion strategy to disrupt both alleles) null BWP17 biofilm formation: normal C. albicans orf19.5548 ORF LYS14 CAL0006172 PMID: 22073120|CGD_REF: CAL0000143592 homozygous diploid, classical genetics null BWP17 viable C. albicans orf19.5548 ORF LYS14 CAL0006172 PMID: 22073120|CGD_REF: CAL0000143592 homozygous diploid, classical genetics null BWP17 colony appearance: abnormal decreased colony wrinkling C. albicans orf19.5548 ORF LYS14 CAL0006172 PMID: 19463063|CGD_REF: CAL0123630 homozygous diploid, systematic mutation set (split-marker transposon insertion strategy to disrupt both alleles) null BWP17 virulence: normal Toll mutant D. melanogaster invasive infection insect infection C. albicans orf19.5548 ORF LYS14 CAL0006172 PMID: 23526879|CGD_REF: CAL0000158852 homozygous diploid, classical genetics null SN152 virulence: decreased mouse intravenous infection C. albicans orf19.5550 ORF MRT4 CAL0006176 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, competitive growth (haploinsufficient phenotype assay, barcode deletion set) null SC5314 resistance to chemicals: decreased tubercidin C. albicans orf19.5550 ORF MRT4 CAL0006176 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.5551 ORF MIF2 CAL0006177 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.5551 ORF MIF2 CAL0006177 PMID: 15272074|CGD_REF: CAL0082070 heterozygous diploid, classical genetics repressible Not recorded inviable C. albicans orf19.5553 ORF CAL0006179 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.5553 ORF CAL0006179 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient YPD medium C. albicans orf19.5553 ORF CAL0006179 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient SC medium C. albicans orf19.5553 ORF CAL0006179 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient YNB medium C. albicans orf19.5553 ORF CAL0006179 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient SLAD medium C. albicans orf19.5555 ORF CAL0006182 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.5555 ORF CAL0006182 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.5555 ORF CAL0006182 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.5555 ORF CAL0006182 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.5557 ORF MNN4-4 CAL0006186 PMID: 15821124|CGD_REF: CAL0104047 homozygous diploid, classical genetics null Not recorded cell wall morphology: abnormal altered cell wall mannans, as detected by decreased Alcian Blue binding C. albicans orf19.5557 ORF MNN4-4 CAL0006186 PMID: 20123707|CGD_REF: CAL0125018 homozygous diploid, classical genetics null CAI-4 resistance to phagocytosis: increased reduced rate of uptake by macrophages in vitro model of infection (bone marrow-derived macrophages) C. albicans orf19.5558 ORF RBF1 CAL0006188 PMID: 9043120|CGD_REF: CAL0081769 homozygous diploid, classical genetics null Other C. albicans germ tube formation: increased rate various liquid and solid media C. albicans orf19.5558 ORF RBF1 CAL0006188 PMID: 20041210|CGD_REF: CAL0124764 homozygous diploid, systematic mutation set null SN152 vegetative growth: decreased YEPD, SD, MM, Spider, or Lee's pH 4.5 media at 30 deg C strongly decreased C. albicans orf19.5558 ORF RBF1 CAL0006188 PMID: 9043120|CGD_REF: CAL0081769 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.5558 ORF RBF1 CAL0006188 PMID: 24450762|CGD_REF: CAL0000173762 homozygous diploid, classical genetics null Other C. albicans viable C. albicans orf19.5558 ORF RBF1 CAL0006188 PMID: 24450762|CGD_REF: CAL0000173762 homozygous diploid, classical genetics null Other C. albicans vegetative growth: decreased rate C. albicans orf19.5558 ORF RBF1 CAL0006188 PMID: 24450762|CGD_REF: CAL0000173762 homozygous diploid, classical genetics null Other C. albicans colony shape: abnormal C. albicans orf19.5558 ORF RBF1 CAL0006188 PMID: 24450762|CGD_REF: CAL0000173762 homozygous diploid, classical genetics null Other C. albicans invasive growth: decreased C. albicans orf19.5558 ORF RBF1 CAL0006188 PMID: 24450762|CGD_REF: CAL0000173762 homozygous diploid, classical genetics null Other C. albicans resistance to chemicals: decreased fluconazole C. albicans orf19.5558 ORF RBF1 CAL0006188 PMID: 24450762|CGD_REF: CAL0000173762 homozygous diploid, classical genetics null Other C. albicans resistance to chemicals: decreased Calcofluor White C. albicans orf19.5558 ORF RBF1 CAL0006188 PMID: 24450762|CGD_REF: CAL0000173762 homozygous diploid, classical genetics null Other C. albicans resistance to chemicals: decreased caspofungin C. albicans orf19.5558 ORF RBF1 CAL0006188 PMID: 24450762|CGD_REF: CAL0000173762 homozygous diploid, classical genetics null Other C. albicans resistance to chemicals: decreased Congo Red C. albicans orf19.5558 ORF RBF1 CAL0006188 PMID: 24450762|CGD_REF: CAL0000173762 homozygous diploid, classical genetics null Other C. albicans respiratory growth: decreased rate C. albicans orf19.5558 ORF RBF1 CAL0006188 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient YPD medium C. albicans orf19.5558 ORF RBF1 CAL0006188 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient SC medium C. albicans orf19.5558 ORF RBF1 CAL0006188 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient SLAD medium C. albicans orf19.5559 ORF RAV2 CAL0006190 PMID: 12773383|CGD_REF: CAL0087974 heterozygous diploid, classical genetics (haploinsufficient phenotype assay) unspecified CAI-4 filamentous growth: increased solid Spider medium or solid YEPD plus serum transposon insertion proximal to, but not within, the ORF C. albicans orf19.5559 ORF RAV2 CAL0006190 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.5559 ORF RAV2 CAL0006190 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.5559 ORF RAV2 CAL0006190 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.5559 ORF RAV2 CAL0006190 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.5561 ORF STE23 CAL0006201 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.5561 ORF STE23 CAL0006201 PMID: 12773383|CGD_REF: CAL0087974 heterozygous diploid, classical genetics (haploinsufficient phenotype assay) unspecified CAI-4 filamentous growth: increased solid Spider medium or solid YEPD plus serum heterozygous transposon insertion C. albicans orf19.5564 ORF CAL0006207 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.5565 ORF HPD1 CAL0006210 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.5565 ORF HPD1 CAL0006210 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.5565 ORF HPD1 CAL0006210 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.5565 ORF HPD1 CAL0006210 PMID: 24497638|CGD_REF: CAL0000173832 homozygous diploid, classical genetics null SC5314 utilization of carbon source: decreased propionate C. albicans orf19.5565 ORF HPD1 CAL0006210 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.5565 ORF HPD1 CAL0006210 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.5566 ORF CAL0006213 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.5567 ORF POP4 CAL0006215 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.5567 ORF POP4 CAL0006215 PMID: 12524333|CGD_REF: CAL0080691 homozygous diploid, systematic mutation set (homozygous insertion mutants generated with URA3-ARG4-URA3 (UAU1) cassette) null BWP17 inviable homozygous null mutant strain could not be recovered, suggesting that the gene is essential under the selection conditions C. albicans orf19.5568 ORF VPS51 CAL0006217 PMID: 19700637|CGD_REF: CAL0124157 homozygous diploid, classical genetics null Not recorded toxin resistance: decreased human beta-defensin 2 C. albicans orf19.5568 ORF VPS51 CAL0006217 PMID: 19700637|CGD_REF: CAL0124157 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased sodium dodecyl sulfate C. albicans orf19.5568 ORF VPS51 CAL0006217 PMID: 19700637|CGD_REF: CAL0124157 homozygous diploid, classical genetics null Not recorded vacuolar morphology: abnormal vacuoles are highly fragmented C. albicans orf19.5568 ORF VPS51 CAL0006217 PMID: 19700637|CGD_REF: CAL0124157 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.5568 ORF VPS51 CAL0006217 PMID: 19700637|CGD_REF: CAL0124157 homozygous diploid, classical genetics null BWP17 hyphal growth: abnormal contact with oral epithelial cells, vascular endothelial cells, or polystyrene produces short and unbranched hyphae C. albicans orf19.5568 ORF VPS51 CAL0006217 PMID: 19700637|CGD_REF: CAL0124157 homozygous diploid, classical genetics null Not recorded oxidative stress resistance: decreased hydrogen peroxide C. albicans orf19.5568 ORF VPS51 CAL0006217 PMID: 19700637|CGD_REF: CAL0124157 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased protamine C. albicans orf19.5568 ORF VPS51 CAL0006217 PMID: 19700637|CGD_REF: CAL0124157 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased Congo Red C. albicans orf19.5568 ORF VPS51 CAL0006217 PMID: 21998592|CGD_REF: CAL0000143471 homozygous diploid, classical genetics null BWP17 virulence: decreased mouse intravenous infection C. albicans orf19.5568 ORF VPS51 CAL0006217 PMID: 24363364|CGD_REF: CAL0000173733 homozygous diploid, classical genetics null BWP17 vacuolar morphology: abnormal multiple small vacuoles C. albicans orf19.5568 ORF VPS51 CAL0006217 PMID: 19700637|CGD_REF: CAL0124157 homozygous diploid, classical genetics null Not recorded virulence: decreased oral epithelial cells and vascular endothelial cells decreased capacity to damage cells in vitro model of infection C. albicans orf19.5568 ORF VPS51 CAL0006217 PMID: 24363364|CGD_REF: CAL0000173733 homozygous diploid, classical genetics null BWP17 viable C. albicans orf19.5568 ORF VPS51 CAL0006217 PMID: 24363364|CGD_REF: CAL0000173733 homozygous diploid, large-scale survey null BWP17 resistance to chemicals: decreased Congo Red C. albicans orf19.5568 ORF VPS51 CAL0006217 PMID: 24363364|CGD_REF: CAL0000173733 homozygous diploid, large-scale survey null BWP17 protein secretion: abnormal Kex2 secreted to the medium KEX2 C. albicans orf19.5568 ORF VPS51 CAL0006217 PMID: 24363364|CGD_REF: CAL0000173733 homozygous diploid, large-scale survey null BWP17 resistance to chemicals: decreased hydrogen peroxide C. albicans orf19.5568 ORF VPS51 CAL0006217 PMID: 24363364|CGD_REF: CAL0000173733 homozygous diploid, large-scale survey null BWP17 resistance to chemicals: decreased sodium dodecyl sulfate C. albicans orf19.5568 ORF VPS51 CAL0006217 PMID: 24363364|CGD_REF: CAL0000173733 homozygous diploid, large-scale survey null BWP17 metal resistance: decreased manganese(2+) C. albicans orf19.5568 ORF VPS51 CAL0006217 PMID: 24363364|CGD_REF: CAL0000173733 homozygous diploid, large-scale survey null BWP17 metal resistance: decreased copper(2+) C. albicans orf19.5568 ORF VPS51 CAL0006217 PMID: 24363364|CGD_REF: CAL0000173733 homozygous diploid, large-scale survey null BWP17 resistance to chemicals: decreased fluconazole C. albicans orf19.5568 ORF VPS51 CAL0006217 PMID: 24363364|CGD_REF: CAL0000173733 homozygous diploid, large-scale survey null BWP17 resistance to chemicals: decreased protamine A C. albicans orf19.5568 ORF VPS51 CAL0006217 PMID: 24363364|CGD_REF: CAL0000173733 homozygous diploid, large-scale survey null BWP17 virulence: decreased protamine A mouse oropharyngeal infection C. albicans orf19.5569 ORF CAL0006219 PMID: 14663094|CGD_REF: CAL0080633 homozygous diploid, systematic mutation set (homozygous insertion mutants generated with URA3-ARG4-URA3 (UAU1) cassette) null BWP17 viable C. albicans orf19.557 ORF CAL0000246 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: increased growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.557 ORF CAL0000246 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.557 ORF CAL0000246 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.557 ORF CAL0000246 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.5574 ORF CAL0006235 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.5574 ORF CAL0006235 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 invasive growth: decreased solid SLAD media C. albicans orf19.5576 ORF CAL0006241 PMID: 12773383|CGD_REF: CAL0087974 heterozygous diploid, classical genetics (haploinsufficient phenotype assay) unspecified CAI-4 filamentous growth: increased solid Spider medium or solid YEPD plus serum transposon insertion proximal to, but not within, the ORF C. albicans orf19.5585 ORF SAP5 CAL0006261 PMID: 12427964|CGD_REF: CAL0081850 homozygous diploid, classical genetics null CAI-4 hyphal growth: normal liquid Lee's medium pH 6.5 at 37 deg C C. albicans orf19.5585 ORF SAP5 CAL0006261 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.5585 ORF SAP5 CAL0006261 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.5585 ORF SAP5 CAL0006261 PMID: 11812212|CGD_REF: CAL0081840 homozygous diploid, classical genetics null Not recorded virulence: normal mouse gastrointestinal tract infection C. albicans orf19.5585 ORF SAP5 CAL0006261 PMID: 9841840|CGD_REF: CAL0081814 homozygous diploid, classical genetics null Not recorded virulence: normal rat vaginal infection C. albicans orf19.5585 ORF SAP5 CAL0006261 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.5585 ORF SAP5 CAL0006261 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.5586 ORF CAL0006264 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.5588 ORF PGA60 CAL0006267 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.5588 ORF PGA60 CAL0006267 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.5588 ORF PGA60 CAL0006267 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.5588 ORF PGA60 CAL0006267 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.559 ORF FGR14 CAL0000254 PMID: 12773383|CGD_REF: CAL0087974 heterozygous diploid, classical genetics (haploinsufficient phenotype assay) unspecified CAI-4 filamentous growth: increased solid YEPD plus serum transposon insertion proximal to, but not within, the ORF C. albicans orf19.5591 ORF ADO1 CAL0006279 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.5591 ORF ADO1 CAL0006279 PMID: 19623926|CGD_REF: CAL0124054 heterozygous diploid, competitive growth (haploinsufficient phenotype assay, barcode deletion set) null SC5314 resistance to chemicals: increased cordycepin C. albicans orf19.5592 ORF CAL0006280 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.5595 ORF SHE3 CAL0006287 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.5595 ORF SHE3 CAL0006287 PMID: 19779551|CGD_REF: CAL0124331 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.5595 ORF SHE3 CAL0006287 PMID: 19779551|CGD_REF: CAL0124331 homozygous diploid, classical genetics null Not recorded RNA localization: abnormal specific mRNA (mRNAs bound by She3p fail to localize to yeast-form daughter cells and/or to hyphal tips) C. albicans orf19.5595 ORF SHE3 CAL0006287 PMID: 19779551|CGD_REF: CAL0124331 homozygous diploid, classical genetics null CAI-4 hyphal growth: abnormal serum-containing or Spider media C. albicans orf19.5595 ORF SHE3 CAL0006287 PMID: 19779551|CGD_REF: CAL0124331 homozygous diploid, classical genetics null CAI-4 colony appearance: abnormal serum-containing or Spider media C. albicans orf19.5595 ORF SHE3 CAL0006287 PMID: 19779551|CGD_REF: CAL0124331 homozygous diploid, classical genetics null Not recorded virulence: decreased oral epithelial cells decreased capacity to damage oral epithelial cells in vitro model of infection C. albicans orf19.5595 ORF SHE3 CAL0006287 PMID: 19779551|CGD_REF: CAL0124331 homozygous diploid, classical genetics null Not recorded virulence: normal primary endothelial cells normal capacity to damage primary endothelial cells in vitro model of infection C. albicans orf19.5596 ORF CAL0006290 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient SLAD medium C. albicans orf19.5597 ORF POL5 CAL0006292 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.5597 ORF POL5 CAL0006292 PMID: 21135205|CGD_REF: CAL0139967 heterozygous diploid, competitive growth (large-scale identification of genes essential for virulence in mouse) repressible CAI-4 virulence: normal mouse intravenous infection C. albicans orf19.56 ORF ARG2 CAL0000606 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.56 ORF ARG2 CAL0000606 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient SC medium C. albicans orf19.5602 ORF BMT6 CAL0000530 PMID: 18234669|CGD_REF: CAL0119018 homozygous diploid, classical genetics null Not recorded resistance to chemicals: normal Calcofluor White C. albicans orf19.5602 ORF BMT6 CAL0000530 PMID: 18234669|CGD_REF: CAL0119018 homozygous diploid, classical genetics null Not recorded viable rich medium wild-type growth rate C. albicans orf19.5602 ORF BMT6 CAL0000530 PMID: 18234669|CGD_REF: CAL0119018 homozygous diploid, classical genetics null Not recorded resistance to chemicals: normal sodium dodecyl sulfate C. albicans orf19.5602 ORF BMT6 CAL0000530 PMID: 18234669|CGD_REF: CAL0119018 homozygous diploid, classical genetics null BWP17 hyphal growth: normal serum-containing medium C. albicans orf19.5602 ORF BMT6 CAL0000530 PMID: 18234669|CGD_REF: CAL0119018 homozygous diploid, classical genetics null Not recorded chlamydospore formation: normal RAT medium C. albicans orf19.5602 ORF BMT6 CAL0000530 PMID: 18234669|CGD_REF: CAL0119018 homozygous diploid, classical genetics null Not recorded ionic stress resistance: normal sodium chloride C. albicans orf19.5602 ORF BMT6 CAL0000530 PMID: 18234669|CGD_REF: CAL0119018 homozygous diploid, classical genetics null Not recorded resistance to chemicals: normal calcium dichloride C. albicans orf19.5604 ORF MDR1 CAL0000532 PMID: 11709317|CGD_REF: CAL0081518 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased brefeldin A C. albicans orf19.5604 ORF MDR1 CAL0000532 PMID: 16569853|CGD_REF: CAL0115750 heterozygous diploid, classical genetics overexpression Not recorded resistance to chemicals: increased brefeldin A C. albicans orf19.5604 ORF MDR1 CAL0000532 PMID: 8891134|CGD_REF: CAL0080887 homozygous diploid, classical genetics null Not recorded resistance to chemicals: normal ketoconazole C. albicans orf19.5604 ORF MDR1 CAL0000532 PMID: 15114480|CGD_REF: CAL0080964 heterozygous diploid, classical genetics overexpression Not recorded oxidative stress resistance: increased 1,1'-azobis(N,N-dimethylformamide) C. albicans orf19.5604 ORF MDR1 CAL0000532 PMID: 8891134|CGD_REF: CAL0080887 homozygous diploid, classical genetics null Not recorded resistance to chemicals: normal itraconazole C. albicans orf19.5604 ORF MDR1 CAL0000532 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.5604 ORF MDR1 CAL0000532 PMID: 15114480|CGD_REF: CAL0080964 heterozygous diploid, classical genetics overexpression Not recorded viable C. albicans orf19.5604 ORF MDR1 CAL0000532 PMID: 7591094|CGD_REF: CAL0081512 heterozygous diploid, classical genetics null Not recorded viable C. albicans orf19.5604 ORF MDR1 CAL0000532 PMID: 7591094|CGD_REF: CAL0081512 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.5604 ORF MDR1 CAL0000532 PMID: 7726508|CGD_REF: CAL0081513 heterozygous diploid, classical genetics null Not recorded viable C. albicans orf19.5604 ORF MDR1 CAL0000532 PMID: 7726508|CGD_REF: CAL0081513 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.5604 ORF MDR1 CAL0000532 PMID: 8891134|CGD_REF: CAL0080887 heterozygous diploid, classical genetics null Not recorded viable C. albicans orf19.5604 ORF MDR1 CAL0000532 PMID: 8891134|CGD_REF: CAL0080887 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.5604 ORF MDR1 CAL0000532 PMID: 10844673|CGD_REF: CAL0081443 heterozygous diploid, classical genetics null MDR1/mdr1::FRT Other C. albicans resistance to chemicals: decreased 4-nitroquinoline N-oxide C. albicans orf19.5604 ORF MDR1 CAL0000532 PMID: 10844673|CGD_REF: CAL0081443 heterozygous diploid, classical genetics null MDR1/mdr1::FRT Other C. albicans resistance to chemicals: decreased fluconazole C. albicans orf19.5604 ORF MDR1 CAL0000532 PMID: 10844673|CGD_REF: CAL0081443 heterozygous diploid, classical genetics null MDR1/mdr1::FRT Other C. albicans viable C. albicans orf19.5604 ORF MDR1 CAL0000532 PMID: 10844673|CGD_REF: CAL0081443 homozygous diploid, classical genetics null mdr1::FRT/mdr1::MPAR-FLIP Other C. albicans resistance to chemicals: decreased 4-nitroquinoline N-oxide C. albicans orf19.5604 ORF MDR1 CAL0000532 PMID: 10844673|CGD_REF: CAL0081443 homozygous diploid, classical genetics null mdr1::FRT/mdr1::MPAR-FLIP Other C. albicans resistance to chemicals: decreased fluconazole C. albicans orf19.5604 ORF MDR1 CAL0000532 PMID: 10844673|CGD_REF: CAL0081443 homozygous diploid, classical genetics null mdr1::FRT/mdr1::MPAR-FLIP Other C. albicans viable C. albicans orf19.5604 ORF MDR1 CAL0000532 PMID: 11709317|CGD_REF: CAL0081518 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased 4-nitroquinoline N-oxide C. albicans orf19.5604 ORF MDR1 CAL0000532 PMID: 7726508|CGD_REF: CAL0081513 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased 4-nitroquinoline N-oxide C. albicans orf19.5604 ORF MDR1 CAL0000532 PMID: 8891134|CGD_REF: CAL0080887 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased 4-nitroquinoline N-oxide C. albicans orf19.5604 ORF MDR1 CAL0000532 PMID: 8891134|CGD_REF: CAL0080887 homozygous diploid, classical genetics null Not recorded resistance to chemicals: normal cycloheximide C. albicans orf19.5604 ORF MDR1 CAL0000532 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, competitive growth (haploinsufficient phenotype assay, barcode deletion set) null SC5314 resistance to chemicals: normal cerulenin C. albicans orf19.5604 ORF MDR1 CAL0000532 PMID: 11709317|CGD_REF: CAL0081518 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased cerulenin C. albicans orf19.5604 ORF MDR1 CAL0000532 PMID: 16569853|CGD_REF: CAL0115750 heterozygous diploid, classical genetics overexpression Not recorded resistance to chemicals: increased cerulenin C. albicans orf19.5604 ORF MDR1 CAL0000532 PMID: 7726508|CGD_REF: CAL0081513 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased methotrexate C. albicans orf19.5604 ORF MDR1 CAL0000532 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, competitive growth (haploinsufficient phenotype assay, barcode deletion set) null SC5314 resistance to chemicals: normal fluconazole C. albicans orf19.5604 ORF MDR1 CAL0000532 PMID: 15328097|CGD_REF: CAL0082113 homozygous diploid, classical genetics null Not recorded resistance to chemicals: increased fluconazole resistance is induced upon adherence to a substrate C. albicans orf19.5604 ORF MDR1 CAL0000532 PMID: 11709317|CGD_REF: CAL0081518 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased fluconazole C. albicans orf19.5604 ORF MDR1 CAL0000532 PMID: 16569853|CGD_REF: CAL0115750 heterozygous diploid, classical genetics overexpression Not recorded resistance to chemicals: increased fluconazole C. albicans orf19.5604 ORF MDR1 CAL0000532 PMID: 8891134|CGD_REF: CAL0080887 homozygous diploid, classical genetics null Not recorded resistance to chemicals: normal fluconazole C. albicans orf19.5604 ORF MDR1 CAL0000532 PMID: 7591094|CGD_REF: CAL0081512 heterozygous diploid, classical genetics null Not recorded virulence: decreased mouse intravenous infection C. albicans orf19.5604 ORF MDR1 CAL0000532 PMID: 7591094|CGD_REF: CAL0081512 homozygous diploid, classical genetics null Not recorded virulence: decreased mouse intravenous infection C. albicans orf19.5605 ORF CAL0000534 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.5608 ORF CAL0000539 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.5610 ORF ARG3 CAL0000556 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.5611 ORF CAL0000557 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.5612 ORF BMT4 CAL0000558 PMID: 18234669|CGD_REF: CAL0119018 homozygous diploid, classical genetics null Not recorded resistance to chemicals: normal Calcofluor White C. albicans orf19.5612 ORF BMT4 CAL0000558 PMID: 18234669|CGD_REF: CAL0119018 homozygous diploid, classical genetics null Not recorded viable rich medium wild-type growth rate C. albicans orf19.5612 ORF BMT4 CAL0000558 PMID: 18234669|CGD_REF: CAL0119018 homozygous diploid, classical genetics null Not recorded resistance to chemicals: normal sodium dodecyl sulfate C. albicans orf19.5612 ORF BMT4 CAL0000558 PMID: 18234669|CGD_REF: CAL0119018 homozygous diploid, classical genetics null BWP17 hyphal growth: normal serum-containing medium C. albicans orf19.5612 ORF BMT4 CAL0000558 PMID: 18234669|CGD_REF: CAL0119018 homozygous diploid, classical genetics null Not recorded cell wall morphology: abnormal strongly decreased beta-mannosylation of both acid-stable and acid-labile fractions of phosphopeptidomannan C. albicans orf19.5612 ORF BMT4 CAL0000558 PMID: 18234669|CGD_REF: CAL0119018 homozygous diploid, classical genetics null Not recorded chlamydospore formation: normal RAT medium C. albicans orf19.5612 ORF BMT4 CAL0000558 PMID: 18234669|CGD_REF: CAL0119018 homozygous diploid, classical genetics null Not recorded ionic stress resistance: normal sodium chloride C. albicans orf19.5612 ORF BMT4 CAL0000558 PMID: 18234669|CGD_REF: CAL0119018 homozygous diploid, classical genetics null Not recorded resistance to chemicals: normal calcium dichloride C. albicans orf19.5615 ORF AYR2 CAL0000562 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.5617 ORF CAL0000566 PMID: 22581526|CGD_REF: CAL0000157314 homozygous diploid, systematic mutation set null BWP17 resistance to chemicals: decreased flucytosine C. albicans orf19.5618 ORF CAL0000568 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.5619 ORF CAL0000570 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.5619 ORF CAL0000570 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.5619 ORF CAL0000570 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.5619 ORF CAL0000570 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.562 ORF FGR13 CAL0000265 PMID: 12773383|CGD_REF: CAL0087974 heterozygous diploid, classical genetics (haploinsufficient phenotype assay) null CAI-4 viable heterozygous deletion or transposon insertion C. albicans orf19.562 ORF FGR13 CAL0000265 PMID: 12773383|CGD_REF: CAL0087974 heterozygous diploid, classical genetics (haploinsufficient phenotype assay) null CAI-4 colony appearance: abnormal solid YEPD plus serum colonies appear striated; heterozygous deletion or transposon insertion C. albicans orf19.562 ORF FGR13 CAL0000265 PMID: 12773383|CGD_REF: CAL0087974 heterozygous diploid, classical genetics (haploinsufficient phenotype assay) null CAI-4 filamentous growth: increased solid YEPD plus serum heterozygous deletion or transposon insertion C. albicans orf19.5621 ORF CAL0000582 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.5621 ORF CAL0000582 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, competitive growth (haploinsufficient phenotype assay, barcode deletion set) null SC5314 resistance to chemicals: decreased amphotericin B C. albicans orf19.5623 ORF ARP4 CAL0000584 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.5623 ORF ARP4 CAL0000584 PMID: 19115836|CGD_REF: CAL0122036 heterozygous diploid, competitive growth (haploinsufficient phenotype assay, barcode deletion set) null SC5314 resistance to chemicals: decreased virgineone C. albicans orf19.5627 ORF CAL0000592 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.5628 ORF CAL0000594 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.563 ORF RRP15 CAL0000267 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.5630 ORF APA2 CAL0000610 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.5634 ORF FRP1 CAL0000614 PMID: 19623957|CGD_REF: CAL0124052 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.5634 ORF FRP1 CAL0000614 PMID: 19623957|CGD_REF: CAL0124052 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased iron chelators C. albicans orf19.5634 ORF FRP1 CAL0000614 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.5634 ORF FRP1 CAL0000614 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.5634 ORF FRP1 CAL0000614 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.5634 ORF FRP1 CAL0000614 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.5635 ORF PGA7 CAL0000616 PMID: 18765290|CGD_REF: CAL0119430 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.5635 ORF PGA7 CAL0000616 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.5635 ORF PGA7 CAL0000616 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.5635 ORF PGA7 CAL0000616 PMID: 23563485|CGD_REF: CAL0000158903 homozygous diploid, classical genetics null pga7::FRT/pga7::FRT SC5314 biofilm formation: abnormal RPMI medium 29 degrees C with rocking for 48 hr mutants have reduced vertical orientation of hyphae, an abnormal extracellular matrix, complete penetrabity to human PMNs, partial impermeability to Sypro Ruby and increased sensitivity to fluconazole C. albicans orf19.5635 ORF PGA7 CAL0000616 PMID: 23563485|CGD_REF: CAL0000158903 heterozygous diploid, classical genetics repressible ADH1/adh1::pTET-PGA7::SATR (tet repressed) P37005 biofilm formation: abnormal RPMI medium 29 degrees C with rocking for 48 hr decreased Sypro Ruby and human PMN penetrability, decreased resistance to fluconazole C. albicans orf19.5635 ORF PGA7 CAL0000616 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.5635 ORF PGA7 CAL0000616 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.5636 ORF RBT5 CAL0000618 PMID: 10978273|CGD_REF: CAL0081429 homozygous diploid, classical genetics null CAI-4 viable no apparent growth defects under various laboratory conditions C. albicans orf19.5636 ORF RBT5 CAL0000618 PMID: 15306022|CGD_REF: CAL0082082 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.5636 ORF RBT5 CAL0000618 PMID: 17042757|CGD_REF: CAL0116848 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.5636 ORF RBT5 CAL0000618 PMID: 18765290|CGD_REF: CAL0119430 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.5636 ORF RBT5 CAL0000618 PMID: 15306022|CGD_REF: CAL0082082 heterozygous diploid, classical genetics null Not recorded utilization of iron source: decreased hemoglobin YPD plus ferrozine medium C. albicans orf19.5636 ORF RBT5 CAL0000618 PMID: 18466294|CGD_REF: CAL0119004 homozygous diploid, classical genetics null Not recorded utilization of iron source: absent hemoglobin C. albicans orf19.5636 ORF RBT5 CAL0000618 PMID: 21414038|CGD_REF: CAL0141808 homozygous diploid, classical genetics null BWP17 viable C. albicans orf19.5636 ORF RBT5 CAL0000618 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.5636 ORF RBT5 CAL0000618 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.5636 ORF RBT5 CAL0000618 PMID: 17042757|CGD_REF: CAL0116848 homozygous diploid, classical genetics null CAI-4 biofilm formation: abnormal C. albicans orf19.5636 ORF RBT5 CAL0000618 PMID: 10978273|CGD_REF: CAL0081429 homozygous diploid, classical genetics null CAI-4 virulence: normal mouse intravenous infection C. albicans orf19.5636 ORF RBT5 CAL0000618 PMID: 10978273|CGD_REF: CAL0081429 homozygous diploid, classical genetics null CAI-4 virulence: normal rabbit corneal infection C. albicans orf19.5636 ORF RBT5 CAL0000618 PMID: 23563485|CGD_REF: CAL0000158903 homozygous diploid, classical genetics null a/alpha rbt5::FRT/rbt5::FRT SC5314 biofilm formation: abnormal RPMI medium 29 degrees C with rocking for 48 hr mutant has decreased thickness of basal poly yeast layer, a slight decrease in hypha production and vertical orientation of hyphae, partial impermeability to Sypro Ruby, complete penetrability by human PMNs and decreased fluconazole resistance C. albicans orf19.5636 ORF RBT5 CAL0000618 PMID: 23563485|CGD_REF: CAL0000158903 heterozygous diploid, classical genetics repressible ADH1/adh1::pTET-RBT5::SATR P37005 biofilm formation: abnormal PMI medium 29 degrees C with rocking for 48 hr decreased Sypro Ruby and human PMN penetrability, decreased resistance to fluconazole C. albicans orf19.5636 ORF RBT5 CAL0000618 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.5636 ORF RBT5 CAL0000618 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.5639 ORF HIS4 CAL0000622 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.5639 ORF HIS4 CAL0000622 PMID: 2163392|CGD_REF: CAL0081378 unknown ploidy, classical genetics unspecified Other C. albicans auxotrophy histidine C. albicans orf19.5639 ORF HIS4 CAL0000622 PMID: 2163392|CGD_REF: CAL0081378 unknown ploidy, classical genetics unspecified Other C. albicans viable C. albicans orf19.5639 ORF HIS4 CAL0000622 PMID: 9673013|CGD_REF: CAL0081379 unknown ploidy, classical genetics unspecified Other C. albicans viable C. albicans orf19.5639 ORF HIS4 CAL0000622 PMID: 9673013|CGD_REF: CAL0081379 unknown ploidy, classical genetics unspecified Other C. albicans adhesion: decreased adhesion to human buccal epithelial cells or human keratinocytes C. albicans orf19.5639 ORF HIS4 CAL0000622 PMID: 17964203|CGD_REF: CAL0118824 homozygous diploid, classical genetics null CAI-4 auxotrophy histidine C. albicans orf19.564 ORF KAR3 CAL0000270 PMID: 18586948|CGD_REF: CAL0119312 homozygous diploid, classical genetics null Not recorded vegetative growth: decreased rate C. albicans orf19.564 ORF KAR3 CAL0000270 PMID: 14663094|CGD_REF: CAL0080633 homozygous diploid, systematic mutation set (homozygous insertion mutants generated with URA3-ARG4-URA3 (UAU1) cassette) null BWP17 viable C. albicans orf19.564 ORF KAR3 CAL0000270 PMID: 18586948|CGD_REF: CAL0119312 homozygous diploid, classical genetics null Not recorded cell cycle progression: abnormal delayed progression through anaphase C. albicans orf19.564 ORF KAR3 CAL0000270 PMID: 18586948|CGD_REF: CAL0119312 homozygous diploid, classical genetics null Not recorded cell shape: abnormal cells are elongated and enlarged C. albicans orf19.564 ORF KAR3 CAL0000270 PMID: 15686553|CGD_REF: CAL0082305 homozygous diploid, classical genetics null Not recorded mating response: abnormal C. albicans orf19.564 ORF KAR3 CAL0000270 PMID: 19458191|CGD_REF: CAL0123591 homozygous diploid, classical genetics null Not recorded phenotypic switching: increased white-to-opaque switching C. albicans orf19.564 ORF KAR3 CAL0000270 PMID: 18586948|CGD_REF: CAL0119312 homozygous diploid, classical genetics null Other C. albicans filamentous growth: abnormal hyphal-inducing conditions mostly pseudohyphae are formed C. albicans orf19.564 ORF KAR3 CAL0000270 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.564 ORF KAR3 CAL0000270 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: abnormal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.564 ORF KAR3 CAL0000270 PMID: 23856128|CGD_REF: CAL0000172540 homozygous diploid, classical genetics null BWP17 resistance to chemicals: decreased propolis C. albicans orf19.564 ORF KAR3 CAL0000270 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: decreased rate liquid synthetic complete medium C. albicans orf19.564 ORF KAR3 CAL0000270 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.5640 ORF PEX5 CAL0000635 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.5640 ORF PEX5 CAL0000635 PMID: 16963628|CGD_REF: CAL0116907 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.5640 ORF PEX5 CAL0000635 PMID: 16963628|CGD_REF: CAL0116907 homozygous diploid, classical genetics null Not recorded utilization of carbon source: absent oleic acid C. albicans orf19.5640 ORF PEX5 CAL0000635 PMID: 18832312|CGD_REF: CAL0120314 homozygous diploid, classical genetics null Not recorded peroxisomal transport: decreased defect in peroxisomal protein import mediated by PTS1 (but not PTS2) targeting sequences C. albicans orf19.5640 ORF PEX5 CAL0000635 PMID: 16963628|CGD_REF: CAL0116907 homozygous diploid, classical genetics null Not recorded utilization of carbon source: decreased fatty acid strongly reduced fatty acid beta-oxidation C. albicans orf19.5641 ORF CAR2 CAL0000636 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.5641 ORF CAR2 CAL0000636 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, competitive growth (haploinsufficient phenotype assay, barcode deletion set) null SC5314 resistance to chemicals: decreased amphotericin B C. albicans orf19.5641 ORF CAR2 CAL0000636 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, competitive growth (haploinsufficient phenotype assay, barcode deletion set) null SC5314 resistance to chemicals: decreased ergosterol analogs (ECC69 and/or ECC1384) C. albicans orf19.5643 ORF ECM7 CAL0000638 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.5643 ORF ECM7 CAL0000638 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.5643 ORF ECM7 CAL0000638 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.5643 ORF ECM7 CAL0000638 PMID: 23769872|CGD_REF: CAL0000172426 homozygous diploid, classical genetics null BWP17 chemical compound accumulation: decreased calcium(2+) under high pH shock C. albicans orf19.5643 ORF ECM7 CAL0000638 PMID: 23769872|CGD_REF: CAL0000172426 homozygous diploid, classical genetics null BWP17 resistance to chemicals: decreased ethylene glycol bis(2-aminoethyl)tetraacetate C. albicans orf19.5643 ORF ECM7 CAL0000638 PMID: 23769872|CGD_REF: CAL0000172426 homozygous diploid, classical genetics null BWP17 oxidative stress resistance: decreased hydrogen peroxide C. albicans orf19.5643 ORF ECM7 CAL0000638 PMID: 23769872|CGD_REF: CAL0000172426 homozygous diploid, classical genetics null BWP17 oxidative stress resistance: decreased menadione C. albicans orf19.5643 ORF ECM7 CAL0000638 PMID: 23769872|CGD_REF: CAL0000172426 homozygous diploid, classical genetics null BWP17 hyphal growth: decreased liquid FBS-containing YPD medium C. albicans orf19.5643 ORF ECM7 CAL0000638 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.5644 ORF CAL0000639 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.5644 ORF CAL0000639 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.5644 ORF CAL0000639 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.5644 ORF CAL0000639 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.5644 ORF CAL0000639 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 invasive growth: decreased solid SLAD media C. albicans orf19.5645 ORF MET15 CAL0000641 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.5645 ORF MET15 CAL0000641 PMID: 10992284|CGD_REF: CAL0081523 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.5645 ORF MET15 CAL0000641 PMID: 16043373|CGD_REF: CAL0114589 heterozygous diploid, classical genetics null Not recorded viable C. albicans orf19.5645 ORF MET15 CAL0000641 PMID: 16043373|CGD_REF: CAL0114589 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.5645 ORF MET15 CAL0000641 PMID: 10992284|CGD_REF: CAL0081523 homozygous diploid, classical genetics null Not recorded auxotrophy methionine C. albicans orf19.5645 ORF MET15 CAL0000641 PMID: 16043373|CGD_REF: CAL0114589 homozygous diploid, classical genetics null Not recorded colony color: abnormal colonies are brown C. albicans orf19.5645 ORF MET15 CAL0000641 PMID: 10992284|CGD_REF: CAL0081523 homozygous diploid, classical genetics null Not recorded colony color: abnormal C. albicans orf19.5647 ORF SUB2 CAL0000645 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.5650 ORF PRO3 CAL0000661 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.5651 ORF CAL0000662 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.5651 ORF CAL0000662 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.5651 ORF CAL0000662 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.5651 ORF CAL0000662 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.5651 ORF CAL0000662 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.5651 ORF CAL0000662 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 invasive growth: decreased solid SLAD media C. albicans orf19.5653 ORF ATP2 CAL0000663 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient SC medium C. albicans orf19.5653 ORF ATP2 CAL0000663 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient SLAD medium C. albicans orf19.5654 ORF STE24 CAL0000665 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.5654 ORF STE24 CAL0000665 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient SLAD medium C. albicans orf19.5655 ORF CAL0000667 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.5655 ORF CAL0000667 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.5655 ORF CAL0000667 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.5655 ORF CAL0000667 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.5657 ORF SWI1 CAL0000671 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.5657 ORF SWI1 CAL0000671 PMID: 16647065|CGD_REF: CAL0116010 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.5657 ORF SWI1 CAL0000671 PMID: 16647065|CGD_REF: CAL0116010 homozygous diploid, classical genetics null CAI-4 hyphal growth: decreased serum-containing or Lee's medium, or solid media C. albicans orf19.5657 ORF SWI1 CAL0000671 PMID: 16647065|CGD_REF: CAL0116010 homozygous diploid, classical genetics null CAI-4 hyphal growth: decreased serum-containing or Lee's medium, or solid media C. albicans orf19.5657 ORF SWI1 CAL0000671 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, competitive growth (haploinsufficient phenotype assay, barcode deletion set) null SC5314 resistance to chemicals: decreased amphotericin B C. albicans orf19.5657 ORF SWI1 CAL0000671 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, competitive growth (haploinsufficient phenotype assay, barcode deletion set) null SC5314 resistance to chemicals: decreased ergosterol analogs (ECC69 and/or ECC1384) C. albicans orf19.5657 ORF SWI1 CAL0000671 PMID: 16647065|CGD_REF: CAL0116010 homozygous diploid, classical genetics null Not recorded virulence: absent mouse intravenous infection C. albicans orf19.5661 ORF PTC7 CAL0000688 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.5661 ORF PTC7 CAL0000688 PMID: 17496972|CGD_REF: CAL0117820 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.5661 ORF PTC7 CAL0000688 PMID: 18708562|CGD_REF: CAL0119375 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.5661 ORF PTC7 CAL0000688 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.5661 ORF PTC7 CAL0000688 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: abnormal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.5661 ORF PTC7 CAL0000688 PMID: 18708562|CGD_REF: CAL0119375 homozygous diploid, classical genetics null Not recorded virulence: normal silkworm insect infection C. albicans orf19.5661 ORF PTC7 CAL0000688 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.5661 ORF PTC7 CAL0000688 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.5662 ORF PEP7 CAL0000689 PMID: 17005990|CGD_REF: CAL0116749 heterozygous diploid, classical genetics null Not recorded metal resistance: normal nickel(2+) C. albicans orf19.5662 ORF PEP7 CAL0000689 PMID: 17005990|CGD_REF: CAL0116749 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased nickel(2+) C. albicans orf19.5662 ORF PEP7 CAL0000689 PMID: 19040629|CGD_REF: CAL0121263 heterozygous diploid, classical genetics repressible Not recorded vacuolar morphology: abnormal fragmented vacuoles in yeast-like cells C. albicans orf19.5662 ORF PEP7 CAL0000689 PMID: 19040629|CGD_REF: CAL0121263 heterozygous diploid, classical genetics repressible Not recorded vacuolar morphology: abnormal increased vacuole content in hyphae C. albicans orf19.5662 ORF PEP7 CAL0000689 PMID: 17005990|CGD_REF: CAL0116749 homozygous diploid, classical genetics null Not recorded vegetative growth: normal rate liquid YPD or Sabouraud media C. albicans orf19.5662 ORF PEP7 CAL0000689 PMID: 12773383|CGD_REF: CAL0087974 heterozygous diploid, classical genetics (haploinsufficient phenotype assay) null CAI-4 viable heterozygous transposon insertion C. albicans orf19.5662 ORF PEP7 CAL0000689 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.5662 ORF PEP7 CAL0000689 PMID: 17005990|CGD_REF: CAL0116749 heterozygous diploid, classical genetics null Not recorded viable C. albicans orf19.5662 ORF PEP7 CAL0000689 PMID: 17005990|CGD_REF: CAL0116749 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.5662 ORF PEP7 CAL0000689 PMID: 17005990|CGD_REF: CAL0116749 heterozygous diploid, classical genetics null Not recorded protein secretion: normal secreted aspartyl protease C. albicans orf19.5662 ORF PEP7 CAL0000689 PMID: 17005990|CGD_REF: CAL0116749 homozygous diploid, classical genetics null Not recorded adhesion: decreased adhesion to human vaginal epithelial cells C. albicans orf19.5662 ORF PEP7 CAL0000689 PMID: 17005990|CGD_REF: CAL0116749 heterozygous diploid, classical genetics null Not recorded adhesion: normal C. albicans orf19.5662 ORF PEP7 CAL0000689 PMID: 19040629|CGD_REF: CAL0121263 heterozygous diploid, classical genetics repressible CAI-4 hyphal growth: abnormal altered branching frequency in hyphae C. albicans orf19.5662 ORF PEP7 CAL0000689 PMID: 17005990|CGD_REF: CAL0116749 homozygous diploid, classical genetics null CAI-4 hyphal growth: abnormal defect in hyphal growth on solid media; yeast-form growth (solid Spider), pseudohyphal (solid serum) C. albicans orf19.5662 ORF PEP7 CAL0000689 PMID: 17005990|CGD_REF: CAL0116749 heterozygous diploid, classical genetics null CAI-4 hyphal growth: normal heterozygous null and reintegrant strains C. albicans orf19.5662 ORF PEP7 CAL0000689 PMID: 17005990|CGD_REF: CAL0116749 homozygous diploid, classical genetics null CAI-4 hyphal growth: delayed pH-induced hyphal growth C. albicans orf19.5662 ORF PEP7 CAL0000689 PMID: 17005990|CGD_REF: CAL0116749 homozygous diploid, classical genetics null CAI-4 hyphal growth: normal liquid Spider, liquid serum media C. albicans orf19.5662 ORF PEP7 CAL0000689 PMID: 17005990|CGD_REF: CAL0116749 heterozygous diploid, classical genetics null Not recorded chlamydospore formation: normal both heterozygous null mutant and reintegrant strains C. albicans orf19.5662 ORF PEP7 CAL0000689 PMID: 17005990|CGD_REF: CAL0116749 homozygous diploid, classical genetics null Not recorded chlamydospore formation: absent solid or liquid media C. albicans orf19.5662 ORF PEP7 CAL0000689 PMID: 17005990|CGD_REF: CAL0116749 homozygous diploid, classical genetics null Not recorded endocytosis: decreased defect in uptake of lipophilic dye (FM4-64); decreased vacuolar staining with wild-type prevacuolar endocytic staining C. albicans orf19.5662 ORF PEP7 CAL0000689 PMID: 17005990|CGD_REF: CAL0116749 heterozygous diploid, classical genetics null Not recorded endocytosis: normal C. albicans orf19.5662 ORF PEP7 CAL0000689 PMID: 17005990|CGD_REF: CAL0116749 homozygous diploid, classical genetics null Not recorded protein secretion: decreased decreased secreted aspartyl protease activity C. albicans orf19.5662 ORF PEP7 CAL0000689 PMID: 17005990|CGD_REF: CAL0116749 heterozygous diploid, classical genetics null Not recorded metal resistance: normal copper(2+) C. albicans orf19.5662 ORF PEP7 CAL0000689 PMID: 17005990|CGD_REF: CAL0116749 homozygous diploid, classical genetics null Not recorded metal resistance: decreased copper(2+) C. albicans orf19.5662 ORF PEP7 CAL0000689 PMID: 17005990|CGD_REF: CAL0116749 heterozygous diploid, classical genetics null Not recorded metal resistance: normal zinc(2+) C. albicans orf19.5662 ORF PEP7 CAL0000689 PMID: 17005990|CGD_REF: CAL0116749 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased zinc(2+) C. albicans orf19.5662 ORF PEP7 CAL0000689 PMID: 17005990|CGD_REF: CAL0116749 homozygous diploid, classical genetics null CAI-4 filamentous growth: increased microaerophilic agar-embedded growth C. albicans orf19.5662 ORF PEP7 CAL0000689 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: decreased growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.5662 ORF PEP7 CAL0000689 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: abnormal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.5662 ORF PEP7 CAL0000689 PMID: 17005990|CGD_REF: CAL0116749 homozygous diploid, classical genetics null Not recorded virulence: absent mouse intravenous infection C. albicans orf19.5662 ORF PEP7 CAL0000689 PMID: 17005990|CGD_REF: CAL0116749 heterozygous diploid, classical genetics null Not recorded virulence: normal mouse intravenous infection C. albicans orf19.5662 ORF PEP7 CAL0000689 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.5662 ORF PEP7 CAL0000689 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.5663 ORF RCH1 CAL0000690 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.5663 ORF RCH1 CAL0000690 PMID: 22530691|CGD_REF: CAL0000157179 homozygous diploid, classical genetics null RM1000 viable C. albicans orf19.5663 ORF RCH1 CAL0000690 PMID: 22530691|CGD_REF: CAL0000157179 homozygous diploid, classical genetics null RM1000 resistance to chemicals: increased ketoconazole C. albicans orf19.5663 ORF RCH1 CAL0000690 PMID: 22530691|CGD_REF: CAL0000157179 homozygous diploid, classical genetics null RM1000 resistance to chemicals: increased fluconazole C. albicans orf19.5663 ORF RCH1 CAL0000690 PMID: 22530691|CGD_REF: CAL0000157179 homozygous diploid, classical genetics null RM1000 resistance to chemicals: increased terbinafine C. albicans orf19.5663 ORF RCH1 CAL0000690 PMID: 22530691|CGD_REF: CAL0000157179 homozygous diploid, classical genetics null RM1000 resistance to chemicals: decreased sodium dodecyl sulfate C. albicans orf19.5663 ORF RCH1 CAL0000690 PMID: 22530691|CGD_REF: CAL0000157179 homozygous diploid, classical genetics null RM1000 resistance to chemicals: increased lithium chloride (0.4 M) C. albicans orf19.5663 ORF RCH1 CAL0000690 PMID: 22530691|CGD_REF: CAL0000157179 homozygous diploid, classical genetics null RM1000 resistance to chemicals: decreased calcium dichloride (0.4 M but not 0.2 M) C. albicans orf19.5663 ORF RCH1 CAL0000690 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient YPD medium C. albicans orf19.5664 ORF HOF1 CAL0000692 PMID: 14663094|CGD_REF: CAL0080633 homozygous diploid, systematic mutation set (homozygous insertion mutants generated with URA3-ARG4-URA3 (UAU1) cassette) null BWP17 viable C. albicans orf19.5665 ORF CAL0000693 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.567 ORF TFB3 CAL0000277 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.567 ORF TFB3 CAL0000277 PMID: 15964282|CGD_REF: CAL0114274 homozygous diploid, systematic mutation set (split-marker transposon insertion strategy to disrupt both alleles) null BWP17 inviable homozygous null mutant strain could not be recovered, suggesting that the gene is essential under the selection conditions C. albicans orf19.5671 ORF CAL0000711 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.5672 ORF MEP2 CAL0000712 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.5672 ORF MEP2 CAL0000712 PMID: 15819622|CGD_REF: CAL0104067 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.5672 ORF MEP2 CAL0000712 PMID: 15819622|CGD_REF: CAL0104067 heterozygous diploid, classical genetics activation CAI-4 filamentous growth: increased solid SLAD medium C-terminal truncation of 40 residues C. albicans orf19.5672 ORF MEP2 CAL0000712 PMID: 15819622|CGD_REF: CAL0104067 homozygous diploid, classical genetics null CAI-4 filamentous growth: absent C. albicans orf19.5673 ORF OPT7 CAL0000713 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.5673 ORF OPT7 CAL0000713 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.5673 ORF OPT7 CAL0000713 PMID: 21994941|CGD_REF: CAL0000143466 homozygous diploid, classical genetics null SC5314 virulence: normal mouse intravenous infection C. albicans orf19.5673 ORF OPT7 CAL0000713 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.5673 ORF OPT7 CAL0000713 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.5674 ORF PGA10 CAL0000715 PMID: 17042757|CGD_REF: CAL0116848 homozygous diploid, classical genetics null Not recorded flocculation: increased C. albicans orf19.5674 ORF PGA10 CAL0000715 PMID: 17042757|CGD_REF: CAL0116848 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased Calcofluor White C. albicans orf19.5674 ORF PGA10 CAL0000715 PMID: 15306022|CGD_REF: CAL0082082 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.5674 ORF PGA10 CAL0000715 PMID: 17042757|CGD_REF: CAL0116848 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.5674 ORF PGA10 CAL0000715 PMID: 17873081|CGD_REF: CAL0118685 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.5674 ORF PGA10 CAL0000715 PMID: 18765290|CGD_REF: CAL0119430 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.5674 ORF PGA10 CAL0000715 PMID: 17042757|CGD_REF: CAL0116848 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased sodium dodecyl sulfate C. albicans orf19.5674 ORF PGA10 CAL0000715 PMID: 17042757|CGD_REF: CAL0116848 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased Congo Red C. albicans orf19.5674 ORF PGA10 CAL0000715 PMID: 18466294|CGD_REF: CAL0119004 homozygous diploid, classical genetics null Not recorded utilization of iron source: absent hemoglobin C. albicans orf19.5674 ORF PGA10 CAL0000715 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.5674 ORF PGA10 CAL0000715 PMID: 19798425|CGD_REF: CAL0124304 homozygous diploid, classical genetics null Other C. albicans biofilm formation: abnormal C. albicans orf19.5674 ORF PGA10 CAL0000715 PMID: 17042757|CGD_REF: CAL0116848 homozygous diploid, classical genetics null CAI-4 biofilm formation: abnormal C. albicans orf19.5674 ORF PGA10 CAL0000715 PMID: 23563485|CGD_REF: CAL0000158903 homozygous diploid, classical genetics null a/alpha pga10::FRT/pga10::FRT SC5314 biofilm formation: abnormal RPMI medium 29 degrees C with rocking for 48 hr mutants have reduced vertical orientation of hyphae, reduced extracellular matrix, increased Sypro Ruby penetrability, complete PMN penetrability and decreased flucoazole resistane C. albicans orf19.5674 ORF PGA10 CAL0000715 PMID: 23563485|CGD_REF: CAL0000158903 heterozygous diploid, classical genetics repressible a/alpha pga10::FRT/pga10::FRT ADH1/adh1::pTET-PGA10::SATR SC5314 biofilm formation: abnormal RPMI medium 29 degrees C with rocking for 48 hr mutants have reduced vertical orientation of hyphae, an abnormal extracellular matrix, complete penetrabity to Sypro Ruby and human PMNs and increased sensitivity to fluconazole C. albicans orf19.5674 ORF PGA10 CAL0000715 PMID: 23563485|CGD_REF: CAL0000158903 heterozygous diploid, classical genetics repressible a/a ADH1/adh1::pTET-PGA10::SATR (tet repressed) P37005 biofilm formation: abnormal RPMI medium 29 degrees C with rocking for 48 hr decreased Sypro Ruby and human PMN penetrability, decreased resistance to fluconazole C. albicans orf19.5674 ORF PGA10 CAL0000715 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: decreased rate liquid synthetic complete medium C. albicans orf19.5674 ORF PGA10 CAL0000715 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.5674 ORF PGA10 CAL0000715 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 invasive growth: decreased solid SLAD media C. albicans orf19.5674 ORF PGA10 CAL0000715 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.5676 ORF CAL0000719 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.5677 ORF DUR4 CAL0000721 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.5682 ORF CAL0000730 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.5685 ORF THS1 CAL0000735 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.5691 ORF CDC11 CAL0000744 PMID: 12181342|CGD_REF: CAL0080842 homozygous diploid, classical genetics null Not recorded heat sensitivity: increased septin ring is temporarily disrupted C. albicans orf19.5691 ORF CDC11 CAL0000744 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.5691 ORF CDC11 CAL0000744 PMID: 17765684|CGD_REF: CAL0118343 heterozygous diploid, classical genetics reduction of function Not recorded viable S394A and S395A mimic unphosphorylated forms, S394D mimics constitutively phosphorylated form C. albicans orf19.5691 ORF CDC11 CAL0000744 PMID: 12181342|CGD_REF: CAL0080842 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.5691 ORF CDC11 CAL0000744 PMID: 12819094|CGD_REF: CAL0080843 heterozygous diploid, classical genetics null Not recorded viable C. albicans orf19.5691 ORF CDC11 CAL0000744 PMID: 12819094|CGD_REF: CAL0080843 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.5691 ORF CDC11 CAL0000744 PMID: 16858141|CGD_REF: CAL0116320 homozygous diploid, classical genetics null Not recorded protein/peptide distribution: abnormal Int1p localization to bud neck is decreased Int1p C. albicans orf19.5691 ORF CDC11 CAL0000744 PMID: 17765684|CGD_REF: CAL0118343 heterozygous diploid, classical genetics reduction of function cdc11-S394A BWP17 hyphal growth: abnormal hyphal growth is initiated but not maintained C. albicans orf19.5691 ORF CDC11 CAL0000744 PMID: 12819094|CGD_REF: CAL0080843 homozygous diploid, classical genetics null BWP17 hyphal growth: normal within macrophages normal hyphal growth upon engulfment by macrophage C. albicans orf19.5691 ORF CDC11 CAL0000744 PMID: 17765684|CGD_REF: CAL0118343 heterozygous diploid, classical genetics reduction of function BWP17 hyphal growth: abnormal S394A mutant displays a defect in maintenance of hyphal growth C. albicans orf19.5691 ORF CDC11 CAL0000744 PMID: 17765684|CGD_REF: CAL0118343 heterozygous diploid, classical genetics reduction of function cdc11-S395A BWP17 germ tube formation: abnormal multiple abortive germ tubes are initiated C. albicans orf19.5691 ORF CDC11 CAL0000744 PMID: 12181342|CGD_REF: CAL0080842 homozygous diploid, classical genetics null BWP17 invasive growth: decreased C. albicans orf19.5691 ORF CDC11 CAL0000744 PMID: 12819094|CGD_REF: CAL0080843 homozygous diploid, classical genetics null BWP17 invasive growth: decreased solid serum-containing medium C. albicans orf19.5691 ORF CDC11 CAL0000744 PMID: 12181342|CGD_REF: CAL0080842 homozygous diploid, classical genetics null Not recorded cellular morphology: abnormal C. albicans orf19.5691 ORF CDC11 CAL0000744 PMID: 12181342|CGD_REF: CAL0080842 homozygous diploid, classical genetics null Not recorded chitin deposition: abnormal C. albicans orf19.5691 ORF CDC11 CAL0000744 PMID: 16002645|CGD_REF: CAL0114398 homozygous diploid, classical genetics null Not recorded chlamydospore formation: abnormal abnormal chlamydospore morphology: septum is lacking at suspensor cell-chlamydospore junction; ectopic chitin deposition in chlamydospores; some multinucleate chlamydospores and suspensor cells C. albicans orf19.5691 ORF CDC11 CAL0000744 PMID: 12181342|CGD_REF: CAL0080842 homozygous diploid, classical genetics null Not recorded cytokinesis: absent C. albicans orf19.5691 ORF CDC11 CAL0000744 PMID: 16002645|CGD_REF: CAL0114398 homozygous diploid, classical genetics null CAI-4 filamentous growth: abnormal curved, kinked filaments C. albicans orf19.5691 ORF CDC11 CAL0000744 PMID: 12819094|CGD_REF: CAL0080843 homozygous diploid, classical genetics null Not recorded virulence: decreased exhibits no tissue invasion mouse intravenous infection C. albicans orf19.5691 ORF CDC11 CAL0000744 PMID: 12819094|CGD_REF: CAL0080843 heterozygous diploid, classical genetics null Not recorded virulence: normal mouse intravenous infection C. albicans orf19.5691 ORF CDC11 CAL0000744 PMID: 20140194|CGD_REF: CAL0124995 homozygous diploid, classical genetics null Other C. albicans resistance to chemicals: decreased caspofungin C. albicans orf19.5692 ORF CAL0000745 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.5693 ORF CAL0000746 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.57 ORF PSF2 CAL0000607 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.570 ORF IFF8 CAL0000295 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.570 ORF IFF8 CAL0000295 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.570 ORF IFF8 CAL0000295 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.570 ORF IFF8 CAL0000295 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.5702 ORF CAL0001355 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.5705 ORF NAM2 CAL0001358 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 invasive growth: decreased solid SLAD media C. albicans orf19.5711 ORF CAL0001373 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 invasive growth: decreased solid SLAD media C. albicans orf19.5713 ORF YMX6 CAL0001374 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.5714 ORF SAP1 CAL0001375 PMID: 9284116|CGD_REF: CAL0081802 homozygous diploid, classical genetics null Not recorded vegetative growth: decreased rate YCB/BSA media C. albicans orf19.5714 ORF SAP1 CAL0001375 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.5714 ORF SAP1 CAL0001375 PMID: 15820985|CGD_REF: CAL0082498 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.5714 ORF SAP1 CAL0001375 PMID: 9284116|CGD_REF: CAL0081802 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.5714 ORF SAP1 CAL0001375 PMID: 9485603|CGD_REF: CAL0081808 homozygous diploid, classical genetics null Not recorded adhesion: decreased adhesion to human buccal epithelial cells C. albicans orf19.5714 ORF SAP1 CAL0001375 PMID: 9596782|CGD_REF: CAL0081875 homozygous diploid, classical genetics null Not recorded adhesion: normal adhesion to human umbilical vein endothelial cells C. albicans orf19.5714 ORF SAP1 CAL0001375 PMID: 15845479|CGD_REF: CAL0082755 homozygous diploid, classical genetics null CAI-4 induction of host response: decreased mutants have a strongly reduced ability to induce gene expression of IL-1beta, IL-8, GM-CSF, IFN-gamma, and TNF-alpha ex vivo model of infection (reconstituted human vaginal epithelium) C. albicans orf19.5714 ORF SAP1 CAL0001375 PMID: 15845479|CGD_REF: CAL0082755 heterozygous diploid, classical genetics null CAI-4 induction of host response: normal wild-type level of IL-1beta, IL-8, GM-CSF, IFN-gamma, and TNF-alpha gene expression ex vivo model of infection (reconstituted human vaginal epithelium) C. albicans orf19.5714 ORF SAP1 CAL0001375 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.5714 ORF SAP1 CAL0001375 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.5714 ORF SAP1 CAL0001375 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.5714 ORF SAP1 CAL0001375 PMID: 12761103|CGD_REF: CAL0081857 homozygous diploid, classical genetics null Not recorded virulence: decreased reconstituted human vaginal epithelium decreased capacity to invade and damage cells ex vivo model of infection C. albicans orf19.5714 ORF SAP1 CAL0001375 PMID: 10733678|CGD_REF: CAL0081828 homozygous diploid, classical genetics null SC5314 virulence: decreased reconstituted human epithelium decreased tissue damage ex vivo model of infection C. albicans orf19.5714 ORF SAP1 CAL0001375 PMID: 10540295|CGD_REF: CAL0081826 homozygous diploid, classical genetics null SC5314 virulence: decreased reconstituted human epithelium ex vivo model of infection C. albicans orf19.5714 ORF SAP1 CAL0001375 PMID: 9284116|CGD_REF: CAL0081802 homozygous diploid, classical genetics null Not recorded virulence: decreased guinea pig intravenous infection C. albicans orf19.5714 ORF SAP1 CAL0001375 PMID: 9596782|CGD_REF: CAL0081875 heterozygous diploid, classical genetics null Not recorded virulence: normal human umbilical vein endothelial cells normal damage to human cells in vitro model of infection C. albicans orf19.5714 ORF SAP1 CAL0001375 PMID: 9596782|CGD_REF: CAL0081875 homozygous diploid, classical genetics null Not recorded virulence: normal human umbilical vein endothelial cells normal damage to human cells in vitro model of infection C. albicans orf19.5714 ORF SAP1 CAL0001375 PMID: 10569787|CGD_REF: CAL0081627 homozygous diploid, classical genetics misexpression WO-1 virulence: increased misexpression in white-phase cells mouse cutaneous infection C. albicans orf19.5714 ORF SAP1 CAL0001375 PMID: 9284116|CGD_REF: CAL0081802 homozygous diploid, classical genetics null Not recorded virulence: decreased mouse intravenous infection C. albicans orf19.5714 ORF SAP1 CAL0001375 PMID: 10569785|CGD_REF: CAL0081876 homozygous diploid, classical genetics null CAI-4 virulence: normal mouse peritoneal infection C. albicans orf19.5714 ORF SAP1 CAL0001375 PMID: 9841840|CGD_REF: CAL0081814 homozygous diploid, classical genetics null Not recorded virulence: decreased rat vaginal infection C. albicans orf19.5714 ORF SAP1 CAL0001375 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.5716 ORF SAP4 CAL0001377 PMID: 12427964|CGD_REF: CAL0081850 homozygous diploid, classical genetics null CAI-4 hyphal growth: normal liquid Lee's medium pH 6.5 at 37 deg C C. albicans orf19.5716 ORF SAP4 CAL0001377 PMID: 21540243|CGD_REF: CAL0141962 homozygous diploid, classical genetics null Other C. albicans induction of host response: decreased reduced induction of the host antifungal peptide gene Drosomycin insect infection (Drosophila model of gastrointestinal tract infection) C. albicans orf19.5716 ORF SAP4 CAL0001377 PMID: 11812212|CGD_REF: CAL0081840 homozygous diploid, classical genetics null Not recorded virulence: normal mouse gastrointestinal tract infection C. albicans orf19.5716 ORF SAP4 CAL0001377 PMID: 9841840|CGD_REF: CAL0081814 homozygous diploid, classical genetics null Not recorded virulence: normal rat vaginal infection C. albicans orf19.5720 ORF CAL0001394 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.5722 ORF CAL0001395 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.5728 ORF CAL0001404 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.5728 ORF CAL0001404 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.5728 ORF CAL0001404 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: decreased rate liquid synthetic complete medium C. albicans orf19.5728 ORF CAL0001404 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.5728 ORF CAL0001404 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.5729 ORF FGR17 CAL0001407 PMID: 12773383|CGD_REF: CAL0087974 heterozygous diploid, classical genetics (haploinsufficient phenotype assay) null CAI-4 viable heterozygous deletion or transposon insertion C. albicans orf19.5729 ORF FGR17 CAL0001407 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.5729 ORF FGR17 CAL0001407 PMID: 15964282|CGD_REF: CAL0114274 homozygous diploid, systematic mutation set (split-marker transposon insertion strategy to disrupt both alleles) null BWP17 viable C. albicans orf19.5729 ORF FGR17 CAL0001407 PMID: 19463063|CGD_REF: CAL0123630 homozygous diploid, systematic mutation set (split-marker transposon insertion strategy to disrupt both alleles) null BWP17 viable C. albicans orf19.5729 ORF FGR17 CAL0001407 PMID: 15964282|CGD_REF: CAL0114274 homozygous diploid, systematic mutation set (split-marker transposon insertion strategy to disrupt both alleles) null BWP17 biofilm formation: normal C. albicans orf19.5729 ORF FGR17 CAL0001407 PMID: 12773383|CGD_REF: CAL0087974 heterozygous diploid, classical genetics (haploinsufficient phenotype assay) null CAI-4 filamentous growth: decreased solid Spider medium heterozygous deletion or transposon insertion C. albicans orf19.5729 ORF FGR17 CAL0001407 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.5729 ORF FGR17 CAL0001407 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.5729 ORF FGR17 CAL0001407 PMID: 22073120|CGD_REF: CAL0000143592 homozygous diploid, classical genetics null BWP17 viable C. albicans orf19.5729 ORF FGR17 CAL0001407 PMID: 22073120|CGD_REF: CAL0000143592 homozygous diploid, classical genetics null BWP17 invasive growth: increased increased agar invasion C. albicans orf19.5729 ORF FGR17 CAL0001407 PMID: 22073120|CGD_REF: CAL0000143592 homozygous diploid, classical genetics null BWP17 viable C. albicans orf19.5729 ORF FGR17 CAL0001407 PMID: 22073120|CGD_REF: CAL0000143592 homozygous diploid, classical genetics null BWP17 hyphal growth: increased C. albicans orf19.5729 ORF FGR17 CAL0001407 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.5729 ORF FGR17 CAL0001407 PMID: 19463063|CGD_REF: CAL0123630 homozygous diploid, systematic mutation set (split-marker transposon insertion strategy to disrupt both alleles) null BWP17 virulence: normal Toll mutant D. melanogaster invasive infection insect infection C. albicans orf19.5729 ORF FGR17 CAL0001407 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient SLAD medium C. albicans orf19.5729 ORF FGR17 CAL0001407 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.5730 ORF CAL0001417 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.5732 ORF NOG2 CAL0001419 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.5732 ORF NOG2 CAL0001419 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient SC medium C. albicans orf19.5732 ORF NOG2 CAL0001419 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 invasive growth: decreased solid SLAD media C. albicans orf19.5734 ORF POP2 CAL0001422 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.5734 ORF POP2 CAL0001422 PMID: 19623926|CGD_REF: CAL0124054 heterozygous diploid, competitive growth (haploinsufficient phenotype assay, barcode deletion set) null SC5314 resistance to chemicals: increased cordycepin C. albicans orf19.5734 ORF POP2 CAL0001422 PMID: 19623926|CGD_REF: CAL0124054 heterozygous diploid, competitive growth (haploinsufficient phenotype assay, barcode deletion set) null SC5314 resistance to chemicals: increased parnafungin C. albicans orf19.5734 ORF POP2 CAL0001422 PMID: 21299651|CGD_REF: CAL0141610 homozygous diploid, classical genetics null pop2::ARG4/pop2::URA3 BWP17 viable C. albicans orf19.5734 ORF POP2 CAL0001422 PMID: 21299651|CGD_REF: CAL0141610 homozygous diploid, classical genetics null pop2::ARG4/pop2::URA3 BWP17 resistance to chemicals: decreased Congo Red C. albicans orf19.5734 ORF POP2 CAL0001422 PMID: 21299651|CGD_REF: CAL0141610 homozygous diploid, classical genetics null pop2::ARG4/pop2::URA3 BWP17 resistance to chemicals: decreased Calcofluor White C. albicans orf19.5734 ORF POP2 CAL0001422 PMID: 21299651|CGD_REF: CAL0141610 homozygous diploid, classical genetics null pop2::ARG4/pop2::URA3 BWP17 resistance to chemicals: decreased caspofungin C. albicans orf19.5734 ORF POP2 CAL0001422 PMID: 21299651|CGD_REF: CAL0141610 homozygous diploid, classical genetics null pop2::ARG4/pop2::URA3 BWP17 filamentous growth: decreased YPD medium with 10% serum or Spider medium C. albicans orf19.5734 ORF POP2 CAL0001422 PMID: 21299651|CGD_REF: CAL0141610 homozygous diploid, classical genetics null pop2::ARG4/pop2::URA3 BWP17 mitochondrial morphology: abnormal C. albicans orf19.5734 ORF POP2 CAL0001422 PMID: 21299651|CGD_REF: CAL0141610 homozygous diploid, classical genetics null pop2::ARG4/pop2::URA3 BWP17 virulence: decreased mouse intravenous infection C. albicans orf19.5736 ORF ALS5 CAL0001426 PMID: 17654269|CGD_REF: CAL0118166 homozygous diploid, classical genetics null Not recorded vegetative growth: decreased rate C. albicans orf19.5736 ORF ALS5 CAL0001426 PMID: 17654269|CGD_REF: CAL0118166 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.5736 ORF ALS5 CAL0001426 PMID: 17654269|CGD_REF: CAL0118166 homozygous diploid, classical genetics null Not recorded adhesion: increased adhesion to human vascular endothelial cell monolayers and buccal epithelial cells C. albicans orf19.5736 ORF ALS5 CAL0001426 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.5736 ORF ALS5 CAL0001426 PMID: 21408122|CGD_REF: CAL0141794 heterozygous diploid, classical genetics dominant negative ALS5-V326N Other C. albicans biofilm formation: decreased substitution peptide inhibited aggregation and biofilm activity when expressed in wild-type cells C. albicans orf19.5736 ORF ALS5 CAL0001426 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.5736 ORF ALS5 CAL0001426 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.5736 ORF ALS5 CAL0001426 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.5736 ORF ALS5 CAL0001426 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 invasive growth: decreased solid SLAD media C. albicans orf19.5741 ORF ALS1 CAL0001440 PMID: 15256583|CGD_REF: CAL0082078 homozygous diploid, classical genetics null Not recorded germ tube formation: decreased rate Lee's medium C. albicans orf19.5741 ORF ALS1 CAL0001440 PMID: 15256583|CGD_REF: CAL0082078 homozygous diploid, classical genetics null Not recorded germ tube formation: normal RPMI medium C. albicans orf19.5741 ORF ALS1 CAL0001440 PMID: 12058169|CGD_REF: CAL0080723 heterozygous diploid, classical genetics null Not recorded viable C. albicans orf19.5741 ORF ALS1 CAL0001440 PMID: 12183577|CGD_REF: CAL0080737 heterozygous diploid, classical genetics null Not recorded viable C. albicans orf19.5741 ORF ALS1 CAL0001440 PMID: 12183577|CGD_REF: CAL0080737 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.5741 ORF ALS1 CAL0001440 PMID: 15042589|CGD_REF: CAL0080741 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.5741 ORF ALS1 CAL0001440 PMID: 11967069|CGD_REF: CAL0080735 heterozygous diploid, classical genetics overexpression Not recorded adhesion: increased 125% increase in adherence to endothelial cells C. albicans orf19.5741 ORF ALS1 CAL0001440 PMID: 11967069|CGD_REF: CAL0080735 homozygous diploid, classical genetics null Not recorded adhesion: decreased 35% reduction in adherence to endothelial cells C. albicans orf19.5741 ORF ALS1 CAL0001440 PMID: 12183577|CGD_REF: CAL0080737 homozygous diploid, classical genetics null Not recorded adhesion: decreased adhesion to mouse tongue ex vivo C. albicans orf19.5741 ORF ALS1 CAL0001440 PMID: 15042589|CGD_REF: CAL0080741 homozygous diploid, classical genetics null Not recorded adhesion: decreased adhesion to human FaDu oropharyngeal epithelial cells C. albicans orf19.5741 ORF ALS1 CAL0001440 PMID: 15256583|CGD_REF: CAL0082078 homozygous diploid, classical genetics null Not recorded adhesion: decreased adhesion to human umbilical vein endothelial cells C. albicans orf19.5741 ORF ALS1 CAL0001440 PMID: 11967069|CGD_REF: CAL0080735 homozygous diploid, classical genetics null Not recorded hyphal growth: abnormal C. albicans orf19.5741 ORF ALS1 CAL0001440 PMID: 12058169|CGD_REF: CAL0080723 heterozygous diploid, classical genetics null Not recorded hyphal growth: decreased some solid media C. albicans orf19.5741 ORF ALS1 CAL0001440 PMID: 12183577|CGD_REF: CAL0080737 heterozygous diploid, classical genetics null CAI-4 hyphal growth: decreased some solid media C. albicans orf19.5741 ORF ALS1 CAL0001440 PMID: 19187560|CGD_REF: CAL0122338 homozygous diploid, classical genetics null SC5314 biofilm formation: abnormal forms biofilm with altered detachment properties C. albicans orf19.5741 ORF ALS1 CAL0001440 PMID: 12183577|CGD_REF: CAL0080737 homozygous diploid, classical genetics null CAI-4 filamentous growth: normal mouse oropharyngeal infection C. albicans orf19.5741 ORF ALS1 CAL0001440 PMID: 22037180|CGD_REF: CAL0000143564 homozygous diploid, classical genetics null als1::hisG/als1::hisG-URA3- hisG CAI-4 flocculation: decreased decreased caspofungin-induced flocculation in caspofungin liquid medium C. albicans orf19.5741 ORF ALS1 CAL0001440 PMID: 18683080|CGD_REF: CAL0119365 homozygous diploid, classical genetics null SC5314 biofilm formation: normal C. albicans orf19.5741 ORF ALS1 CAL0001440 PMID: 15256583|CGD_REF: CAL0082078 homozygous diploid, classical genetics null Not recorded virulence: decreased reconstituted human buccal epithelium ex vivo model of infection C. albicans orf19.5741 ORF ALS1 CAL0001440 PMID: 15042589|CGD_REF: CAL0080741 homozygous diploid, classical genetics null Not recorded virulence: decreased exhibits decreased kidney and brain colonization mouse intravenous infection C. albicans orf19.5741 ORF ALS1 CAL0001440 PMID: 15042589|CGD_REF: CAL0080741 homozygous diploid, classical genetics null Not recorded virulence: decreased mouse intravenous infection C. albicans orf19.5741 ORF ALS1 CAL0001440 PMID: 12183577|CGD_REF: CAL0080737 homozygous diploid, classical genetics null Not recorded virulence: decreased decreased virulence at early timepoints after infection, smaller infectious foci mouse oropharyngeal infection C. albicans orf19.5741 ORF ALS1 CAL0001440 PMID: 12183577|CGD_REF: CAL0080737 heterozygous diploid, classical genetics null Not recorded virulence: normal mouse oropharyngeal infection C. albicans orf19.5741 ORF ALS1 CAL0001440 PMID: 11967069|CGD_REF: CAL0080735 homozygous diploid, classical genetics null Not recorded virulence: decreased C. albicans orf19.5742 ORF ALS9 CAL0001441 PMID: 17600078|CGD_REF: CAL0118031 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.5742 ORF ALS9 CAL0001441 PMID: 17600078|CGD_REF: CAL0118031 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.5742 ORF ALS9 CAL0001441 PMID: 17600078|CGD_REF: CAL0118031 homozygous diploid, classical genetics null Not recorded adhesion: decreased adhesion to human vascular endothelial cell monolayers C. albicans orf19.5746 ORF ALA1 CAL0001447 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.575 ORF HYR3 CAL0000304 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.575 ORF HYR3 CAL0000304 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.575 ORF HYR3 CAL0000304 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.575 ORF HYR3 CAL0000304 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.575 ORF HYR3 CAL0000304 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.5750 ORF SHM2 CAL0001464 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 invasive growth: decreased solid SLAD media C. albicans orf19.5751 ORF ORM1 CAL0001465 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.5751 ORF ORM1 CAL0001465 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, competitive growth (haploinsufficient phenotype assay, barcode deletion set) null SC5314 resistance to chemicals: decreased Aureobasidin A C. albicans orf19.5752 ORF CAL0001466 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.5753 ORF HGT10 CAL0001467 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.5753 ORF HGT10 CAL0001467 PMID: 19383674|CGD_REF: CAL0122777 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.5753 ORF HGT10 CAL0001467 PMID: 19383674|CGD_REF: CAL0122777 homozygous diploid, classical genetics null Not recorded utilization of carbon source: decreased glycerol C. albicans orf19.5755 ORF CAL0001471 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.5757 ORF CAL0001474 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.5758 ORF SAL6 CAL0001476 PMID: 18708562|CGD_REF: CAL0119375 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.5758 ORF SAL6 CAL0001476 PMID: 18708562|CGD_REF: CAL0119375 homozygous diploid, classical genetics null Not recorded virulence: decreased insect infection C. albicans orf19.5759 ORF SNQ2 CAL0001479 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.5759 ORF SNQ2 CAL0001479 PMID: 12773383|CGD_REF: CAL0087974 heterozygous diploid, classical genetics (haploinsufficient phenotype assay) null CAI-4 filamentous growth: decreased solid Spider medium heterozygous transposon insertion C. albicans orf19.5759 ORF SNQ2 CAL0001479 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.5759 ORF SNQ2 CAL0001479 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.5759 ORF SNQ2 CAL0001479 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.5759 ORF SNQ2 CAL0001479 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient SC medium C. albicans orf19.5759 ORF SNQ2 CAL0001479 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.5760 ORF IHD1 CAL0001488 PMID: 14663094|CGD_REF: CAL0080633 homozygous diploid, systematic mutation set (homozygous insertion mutants generated with URA3-ARG4-URA3 (UAU1) cassette) null BWP17 viable C. albicans orf19.5760 ORF IHD1 CAL0001488 PMID: 18765290|CGD_REF: CAL0119430 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.5760 ORF IHD1 CAL0001488 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.5760 ORF IHD1 CAL0001488 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.5760 ORF IHD1 CAL0001488 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.5760 ORF IHD1 CAL0001488 PMID: 23516516|CGD_REF: CAL0000158761 homozygous diploid, classical genetics null SC5314 filamentous growth: normal C. albicans orf19.5760 ORF IHD1 CAL0001488 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.5763 ORF CAL0001490 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.5764 ORF SKI8 CAL0001491 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient SC medium C. albicans orf19.5765 ORF NUP82 CAL0001492 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.5768 ORF SNF4 CAL0001497 PMID: 12773383|CGD_REF: CAL0087974 heterozygous diploid, classical genetics (haploinsufficient phenotype assay) null CAI-4 viable heterozygous transposon insertion C. albicans orf19.5768 ORF SNF4 CAL0001497 PMID: 12773383|CGD_REF: CAL0087974 heterozygous diploid, classical genetics (haploinsufficient phenotype assay) null CAI-4 filamentous growth: decreased solid Spider medium heterozygous transposon insertion C. albicans orf19.5768 ORF SNF4 CAL0001497 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: decreased growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.5768 ORF SNF4 CAL0001497 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, classical genetics null SN152 germ tube formation: decreased serum-containing medium C. albicans orf19.5768 ORF SNF4 CAL0001497 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.5770 ORF OPT8 CAL0001509 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.5771 ORF PBP2 CAL0001510 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.5773 ORF CAL0001512 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.5776 ORF TOM1 CAL0001517 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: decreased growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.5776 ORF TOM1 CAL0001517 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: abnormal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.5776 ORF TOM1 CAL0001517 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: decreased rate liquid synthetic complete medium C. albicans orf19.5776 ORF TOM1 CAL0001517 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.5777 ORF CAL0001519 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.5779 ORF RNR1 CAL0001524 PMID: 12773383|CGD_REF: CAL0087974 heterozygous diploid, classical genetics (haploinsufficient phenotype assay) null CAI-4 viable heterozygous transposon insertion C. albicans orf19.5779 ORF RNR1 CAL0001524 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.5779 ORF RNR1 CAL0001524 PMID: 14507372|CGD_REF: CAL0088818 heterozygous diploid, large-scale survey (large-scale identification of essential genes by gene replacement and conditional expression (GRACE) method) repressible CAI-4 inviable one allele is deleted and the other is placed under repressible Tet promoter C. albicans orf19.5779 ORF RNR1 CAL0001524 PMID: 12773383|CGD_REF: CAL0087974 heterozygous diploid, classical genetics (haploinsufficient phenotype assay) unspecified CAI-4 filamentous growth: increased solid Spider medium transposon insertion proximal to, but not within, the ORF C. albicans orf19.5779 ORF RNR1 CAL0001524 PMID: 12773383|CGD_REF: CAL0087974 heterozygous diploid, classical genetics (haploinsufficient phenotype assay) unspecified CAI-4 colony size: decreased solid Spider medium ransposon insertion proximal to, but not within, the ORF C. albicans orf19.578 ORF CAL0000314 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.578 ORF CAL0000314 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 invasive growth: decreased solid SLAD media C. albicans orf19.5780 ORF CAL0001534 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.5782 ORF CAL0001535 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.5782 ORF CAL0001535 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: increased growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.5782 ORF CAL0001535 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.5782 ORF CAL0001535 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.5782 ORF CAL0001535 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.5784 ORF AMO1 CAL0001538 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.5788 ORF EFT2 CAL0001544 PMID: 10095118|CGD_REF: CAL0081201 heterozygous diploid, classical genetics repressible RM1000 inviable C. albicans orf19.5788 ORF EFT2 CAL0001544 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient YNB medium C. albicans orf19.5788 ORF EFT2 CAL0001544 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient SLAD medium C. albicans orf19.5788 ORF EFT2 CAL0001544 PMID: 21135205|CGD_REF: CAL0139967 heterozygous diploid, large-scale survey (large-scale identification of genes essential for virulence in mouse) repressible CAI-4 virulence: absent mouse intravenous infection C. albicans orf19.5789 ORF ADE8 CAL0001546 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.5789 ORF ADE8 CAL0001546 PMID: 20082641|CGD_REF: CAL0124782 homozygous diploid, classical genetics null viable C. albicans orf19.5789 ORF ADE8 CAL0001546 PMID: 20082641|CGD_REF: CAL0124782 homozygous diploid, classical genetics null auxotrophy adenine C. albicans orf19.5789 ORF ADE8 CAL0001546 PMID: 20082641|CGD_REF: CAL0124782 homozygous diploid, classical genetics null resistance to chemicals: decreased methotrexate C. albicans orf19.5789 ORF ADE8 CAL0001546 PMID: 20082641|CGD_REF: CAL0124782 heterozygous diploid, classical genetics null viable C. albicans orf19.5789 ORF ADE8 CAL0001546 PMID: 20082641|CGD_REF: CAL0124782 homozygous diploid, classical genetics null virulence: decreased completely avirulent mouse intravenous infection C. albicans orf19.5789 ORF ADE8 CAL0001546 PMID: 20082641|CGD_REF: CAL0124782 heterozygous diploid, classical genetics null virulence: decreased partially attentuated compared to wild-type conrols (unknown which allele was disrupted in heterozygous null) C. albicans orf19.579 ORF FOL1 CAL0000317 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.5791 ORF IDH2 CAL0001550 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.5792 ORF SMP3 CAL0001551 PMID: 15470093|CGD_REF: CAL0082147 heterozygous diploid, classical genetics repressible Not recorded resistance to chemicals: decreased Calcofluor White C. albicans orf19.5792 ORF SMP3 CAL0001551 PMID: 15470093|CGD_REF: CAL0082147 heterozygous diploid, classical genetics repressible Not recorded vegetative growth: decreased rate C. albicans orf19.5792 ORF SMP3 CAL0001551 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.5792 ORF SMP3 CAL0001551 PMID: 15470093|CGD_REF: CAL0082147 heterozygous diploid, classical genetics null Not recorded viable C. albicans orf19.5792 ORF SMP3 CAL0001551 PMID: 15470093|CGD_REF: CAL0082147 heterozygous diploid, classical genetics repressible Not recorded cellular morphology: abnormal mutant forms aggregates containing abnormal, enlarged, and dead cells C. albicans orf19.5792 ORF SMP3 CAL0001551 PMID: 15470093|CGD_REF: CAL0082147 homozygous diploid, classical genetics null Not recorded inviable homozygous null mutant strain could not be recovered, suggesting that the gene is essential under the selection conditions C. albicans orf19.5793 ORF PR26 CAL0001552 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.5796 ORF SHE9 CAL0001555 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.5797 ORF PLC2 CAL0001556 PMID: 16207920|CGD_REF: CAL0114770 homozygous diploid, classical genetics null Not recorded viable minimal or rich media wild-type growth rate C. albicans orf19.5797 ORF PLC2 CAL0001556 PMID: 16040234|CGD_REF: CAL0114661 homozygous diploid, classical genetics null BWP17 resistance to killing by host cells: normal MOI of 0.1 in vitro model of infection (J774 macrophages) C. albicans orf19.5797 ORF PLC2 CAL0001556 PMID: 16040234|CGD_REF: CAL0114661 homozygous diploid, classical genetics null BWP17 resistance to phagocytosis: normal in vitro model of infection (J774 macrophages) C. albicans orf19.5798 ORF LIG4 CAL0001558 PMID: 11119499|CGD_REF: CAL0081478 heterozygous diploid, classical genetics null Not recorded viable C. albicans orf19.5798 ORF LIG4 CAL0001558 PMID: 11119499|CGD_REF: CAL0081478 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.5798 ORF LIG4 CAL0001558 PMID: 11119499|CGD_REF: CAL0081478 heterozygous diploid, classical genetics null Not recorded filamentous growth: decreased various solid media phenotype is intermediate between that of wild type and the homozygous null mutant C. albicans orf19.5798 ORF LIG4 CAL0001558 PMID: 11119499|CGD_REF: CAL0081478 homozygous diploid, classical genetics null Not recorded filamentous growth: decreased solid Spider, pH 6.8, 7.3, 7.36; solid YPD, solid M199 at pH 6.8; liquid Spider medium; liquid M199 C. albicans orf19.5798 ORF LIG4 CAL0001558 PMID: 11119499|CGD_REF: CAL0081478 heterozygous diploid, classical genetics null Not recorded virulence: decreased mouse intravenous infection C. albicans orf19.5798 ORF LIG4 CAL0001558 PMID: 11119499|CGD_REF: CAL0081478 homozygous diploid, classical genetics null Not recorded virulence: decreased mouse intravenous infection C. albicans orf19.5798 ORF LIG4 CAL0001558 PMID: 16299301|CGD_REF: CAL0114215 homozygous diploid, classical genetics null Not recorded virulence: decreased mouse intravenous infection C. albicans orf19.5799 ORF CAL0001560 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient YNB medium C. albicans orf19.58 ORF RRP6 CAL0000608 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, competitive growth (haploinsufficient phenotype assay, barcode deletion set) null SC5314 resistance to chemicals: decreased 5-fluorouracil C. albicans orf19.58 ORF RRP6 CAL0000608 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, competitive growth (haploinsufficient phenotype assay, barcode deletion set) null SC5314 resistance to chemicals: decreased tubercidin C. albicans orf19.58 ORF RRP6 CAL0000608 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, competitive growth (haploinsufficient phenotype assay, barcode deletion set) null SC5314 resistance to chemicals: decreased flucytosine C. albicans orf19.58 ORF RRP6 CAL0000608 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.58 ORF RRP6 CAL0000608 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient SC medium C. albicans orf19.58 ORF RRP6 CAL0000608 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 invasive growth: decreased solid SLAD media C. albicans orf19.580 ORF CAL0000326 PMID: 14663094|CGD_REF: CAL0080633 homozygous diploid, systematic mutation set (homozygous insertion mutants generated with URA3-ARG4-URA3 (UAU1) cassette) null BWP17 viable C. albicans orf19.5801 ORF RNR21 CAL0002245 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.5801 ORF RNR21 CAL0002245 PMID: 17182857|CGD_REF: CAL0117321 heterozygous diploid, classical genetics repressible Not recorded cell shape: abnormal elongated cells C. albicans orf19.5801 ORF RNR21 CAL0002245 PMID: 17182857|CGD_REF: CAL0117321 homozygous diploid, classical genetics null Not recorded inviable homozygous null mutant strain could not be recovered, suggesting that the gene is essential under the selection conditions C. albicans orf19.5802 ORF CAL0002246 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.5806 ORF ALD5 CAL0002252 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.5806 ORF ALD5 CAL0002252 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 invasive growth: decreased solid SLAD media C. albicans orf19.5808 ORF CAL0002256 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.5808 ORF CAL0002256 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient YNB medium C. albicans orf19.5809 ORF CAL0002259 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.581 ORF CAL0000328 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.5811 ORF MET1 CAL0002271 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.5811 ORF MET1 CAL0002271 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, competitive growth (haploinsufficient phenotype assay, barcode deletion set) null SC5314 resistance to chemicals: decreased amphotericin B C. albicans orf19.5811 ORF MET1 CAL0002271 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, competitive growth (haploinsufficient phenotype assay, barcode deletion set) null SC5314 resistance to chemicals: decreased ergosterol analogs (ECC69 and/or ECC1384) C. albicans orf19.5811 ORF MET1 CAL0002271 PMID: 6358187|CGD_REF: CAL0080660 unknown ploidy, classical genetics unspecified Other C. albicans auxotrophy methionine C. albicans orf19.5811 ORF MET1 CAL0002271 PMID: 6754707|CGD_REF: CAL0082625 unknown ploidy, classical genetics unspecified Other C. albicans auxotrophy methionine later papers mention that this strain contains a met1 allele C. albicans orf19.5811 ORF MET1 CAL0002271 PMID: 6754707|CGD_REF: CAL0082625 unknown ploidy, classical genetics unspecified Other C. albicans viable later papers mention that this strain contains a met1 allele C. albicans orf19.5813 ORF CAL0002273 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.5813 ORF CAL0002273 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.5813 ORF CAL0002273 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.5813 ORF CAL0002273 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.5815 ORF SCT2 CAL0002276 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.5816 ORF EBP7 CAL0002278 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.5816 ORF EBP7 CAL0002278 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, competitive growth (haploinsufficient phenotype assay, barcode deletion set) null SC5314 resistance to chemicals: decreased ergosterol analogs (ECC69 and/or ECC1384) C. albicans orf19.5817 ORF CAL0002279 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.5818 ORF SUR2 CAL0002282 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.5825 ORF NCB2 CAL0002303 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.5826 ORF CAL0002305 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.5826 ORF CAL0002305 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient YPD medium C. albicans orf19.5826 ORF CAL0002305 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient SC medium C. albicans orf19.5826 ORF CAL0002305 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient YNB medium C. albicans orf19.5826 ORF CAL0002305 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient SLAD medium C. albicans orf19.5827 ORF BUB2 CAL0002306 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.5827 ORF BUB2 CAL0002306 PMID: 16091036|CGD_REF: CAL0114514 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.5827 ORF BUB2 CAL0002306 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, competitive growth (haploinsufficient phenotype assay, barcode deletion set) null SC5314 resistance to chemicals: decreased amphotericin B C. albicans orf19.583 ORF CAL0000331 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.5830 ORF LHS1 CAL0002323 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.5830 ORF LHS1 CAL0002323 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 invasive growth: decreased solid SLAD media C. albicans orf19.5832 ORF HPT1 CAL0002325 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.5832 ORF HPT1 CAL0002325 PMID: 23572557|CGD_REF: CAL0000158900 homozygous diploid, classical genetics null BWP17 resistance to chemicals: increased fluconazole RPMI+MOPS+Histidine medium , 6 hours without shaking at 37 degrees C 24 hr fluconazole treatment in 96 well plates C. albicans orf19.5833 ORF CAL0002326 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.5834 ORF CAL0002327 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.5835 ORF CAL0002329 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.5837 ORF CAL0002332 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.5838 ORF SER2 CAL0002335 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.5839 ORF PDR17 CAL0002337 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.5839 ORF PDR17 CAL0002337 PMID: 17604452|CGD_REF: CAL0118249 homozygous diploid, classical genetics null SC5314 viable C. albicans orf19.5839 ORF PDR17 CAL0002337 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, competitive growth (haploinsufficient phenotype assay, barcode deletion set) null SC5314 resistance to chemicals: decreased fluconazole C. albicans orf19.5839 ORF PDR17 CAL0002337 PMID: 17604452|CGD_REF: CAL0118249 homozygous diploid, classical genetics null SC5314 resistance to chemicals: decreased fluconazole specifically hypersensitive to fluconazole C. albicans orf19.584 ORF CAL0000335 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.584 ORF CAL0000335 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.584 ORF CAL0000335 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.584 ORF CAL0000335 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.5842 ORF CAL0002349 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 invasive growth: decreased solid SLAD media C. albicans orf19.5843 ORF SRR1 CAL0002350 PMID: 21841121|CGD_REF: CAL0000142791 homozygous diploid, classical genetics null Other C. albicans viable C. albicans orf19.5843 ORF SRR1 CAL0002350 PMID: 21841121|CGD_REF: CAL0000142791 homozygous diploid, classical genetics null Other C. albicans vegetative growth: decreased rate C. albicans orf19.5843 ORF SRR1 CAL0002350 PMID: 21841121|CGD_REF: CAL0000142791 homozygous diploid, classical genetics null Other C. albicans oxidative stress resistance: decreased hydrogen peroxide C. albicans orf19.5843 ORF SRR1 CAL0002350 PMID: 21841121|CGD_REF: CAL0000142791 homozygous diploid, classical genetics null Other C. albicans hyperosmotic stress resistance: decreased sodium chloride C. albicans orf19.5843 ORF SRR1 CAL0002350 PMID: 21841121|CGD_REF: CAL0000142791 homozygous diploid, classical genetics null Other C. albicans virulence: decreased mouse intravenous infection C. albicans orf19.5843 ORF SRR1 CAL0002350 PMID: 22164221|CGD_REF: CAL0000143752 homozygous diploid, classical genetics null RM1000 viable C. albicans orf19.5843 ORF SRR1 CAL0002350 PMID: 22164221|CGD_REF: CAL0000143752 homozygous diploid, classical genetics null RM1000 oxidative stress resistance: decreased hydrogen peroxide C. albicans orf19.5843 ORF SRR1 CAL0002350 PMID: 22164221|CGD_REF: CAL0000143752 homozygous diploid, classical genetics null RM1000 hyperosmotic stress resistance: normal sodium chloride (other agents tested include KCl, sorbitol) C. albicans orf19.5843 ORF SRR1 CAL0002350 PMID: 22164221|CGD_REF: CAL0000143752 homozygous diploid, classical genetics null RM1000 resistance to chemicals: normal caffeine (other chemicals tested include cadmium, arsenic, fluconazole, nystatin) C. albicans orf19.5843 ORF SRR1 CAL0002350 PMID: 22164221|CGD_REF: CAL0000143752 homozygous diploid, classical genetics reduction of function srr1(Crr1-D/N) (mutation removes putative phosphorylation site) RM1000 oxidative stress resistance: decreased hydrogen peroxide C. albicans orf19.5843 ORF SRR1 CAL0002350 PMID: 22164221|CGD_REF: CAL0000143752 homozygous diploid, classical genetics null RM1000 virulence: normal mouse intravenous infection C. albicans orf19.5843 ORF SRR1 CAL0002350 PMID: 23584995|CGD_REF: CAL0000158942 homozygous diploid, classical genetics null srr1::CmLEU2/srr1::CdHIS1 Other C. albicans apoptosis: increased C. albicans orf19.5846 ORF CAL0002355 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.5847 ORF CAL0002357 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.5848 ORF CAL0002360 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.5848 ORF CAL0002360 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.5848 ORF CAL0002360 PMID: 22438810|CGD_REF: CAL0000156986 homozygous diploid, classical genetics null BWP17 viable C. albicans orf19.5848 ORF CAL0002360 PMID: 22438810|CGD_REF: CAL0000156986 homozygous diploid, classical genetics null BWP17 virulence: decreased mutants have reduced capacity to damage oral epithelial cells in vitro model of infection (monolayers of oral epithelial cells) C. albicans orf19.5848 ORF CAL0002360 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.5848 ORF CAL0002360 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.5849 ORF CWT1 CAL0002363 PMID: 13129622|CGD_REF: CAL0081099 homozygous diploid, classical genetics null Other C. albicans germ tube formation: normal C. albicans orf19.5849 ORF CWT1 CAL0002363 PMID: 13129622|CGD_REF: CAL0081099 homozygous diploid, classical genetics null Not recorded resistance to enzymatic treatment: increased zymolyase C. albicans orf19.5849 ORF CWT1 CAL0002363 PMID: 13129622|CGD_REF: CAL0081099 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased Calcofluor White C. albicans orf19.5849 ORF CWT1 CAL0002363 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.5849 ORF CWT1 CAL0002363 PMID: 13129622|CGD_REF: CAL0081099 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.5849 ORF CWT1 CAL0002363 PMID: 19908200|CGD_REF: CAL0124546 homozygous diploid, classical genetics null cwt1::ARG5,6/cwt1::HIS1 colony shape: abnormal small and wrinkled colonies C. albicans orf19.5849 ORF CWT1 CAL0002363 PMID: 19908200|CGD_REF: CAL0124546 homozygous diploid, classical genetics null cwt1::ARG5,6/cwt1::HIS1 colony size: abnormal small and wrinkled colonies C. albicans orf19.5849 ORF CWT1 CAL0002363 PMID: 19908200|CGD_REF: CAL0124546 homozygous diploid, classical genetics null cwt1::ARG5,6/cwt1::HIS1 virulence: normal mouse intravenous infection C. albicans orf19.5849 ORF CWT1 CAL0002363 PMID: 19908200|CGD_REF: CAL0124546 homozygous diploid, classical genetics null cwt1::ARG5,6/cwt1::HIS1 filamentous growth: decreased attenuated filamentation on Spider medium C. albicans orf19.5849 ORF CWT1 CAL0002363 PMID: 19908200|CGD_REF: CAL0124546 homozygous diploid, classical genetics null cwt1::ARG5,6/cwt1::HIS1 resistance to chemicals: decreased ketoconazole C. albicans orf19.5849 ORF CWT1 CAL0002363 PMID: 19908200|CGD_REF: CAL0124546 heterozygous diploid, classical genetics null cwt1::ARG5,6/cwt1::HIS1 virulence: absent mouse intravenous infection C. albicans orf19.5849 ORF CWT1 CAL0002363 PMID: 13129622|CGD_REF: CAL0081099 homozygous diploid, classical genetics null Not recorded resistance to chemicals: increased sodium dodecyl sulfate C. albicans orf19.5849 ORF CWT1 CAL0002363 PMID: 13129622|CGD_REF: CAL0081099 homozygous diploid, classical genetics null Not recorded chemical compound accumulation: decreased beta-D-glucan decreased cell wall beta-glucan C. albicans orf19.5849 ORF CWT1 CAL0002363 PMID: 13129622|CGD_REF: CAL0081099 homozygous diploid, classical genetics null Not recorded chemical compound accumulation: increased mannan increased cell wall mannan C. albicans orf19.5849 ORF CWT1 CAL0002363 PMID: 13129622|CGD_REF: CAL0081099 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased Congo Red C. albicans orf19.5849 ORF CWT1 CAL0002363 PMID: 22073120|CGD_REF: CAL0000143592 homozygous diploid, classical genetics null BWP17 viable C. albicans orf19.5849 ORF CWT1 CAL0002363 PMID: 22073120|CGD_REF: CAL0000143592 homozygous diploid, classical genetics null BWP17 heat sensitivity: decreased Increased susceptibility to 42 degrees C heat C. albicans orf19.5849 ORF CWT1 CAL0002363 PMID: 22073120|CGD_REF: CAL0000143592 homozygous diploid, classical genetics null BWP17 hyphal growth: decreased C. albicans orf19.5850 ORF NOC2 CAL0002373 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, competitive growth (haploinsufficient phenotype assay, barcode deletion set) null SC5314 resistance to chemicals: decreased 5-fluorouracil C. albicans orf19.5850 ORF NOC2 CAL0002373 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, competitive growth (haploinsufficient phenotype assay, barcode deletion set) null SC5314 resistance to chemicals: decreased tubercidin C. albicans orf19.5850 ORF NOC2 CAL0002373 PMID: 12773383|CGD_REF: CAL0087974 heterozygous diploid, classical genetics (haploinsufficient phenotype assay) null CAI-4 viable heterozygous transposon insertion C. albicans orf19.5850 ORF NOC2 CAL0002373 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.5850 ORF NOC2 CAL0002373 PMID: 12773383|CGD_REF: CAL0087974 heterozygous diploid, classical genetics (haploinsufficient phenotype assay) null CAI-4 filamentous growth: decreased solid Spider medium or solid YEPD plus serum heterozygous transposon insertion C. albicans orf19.5851 ORF STE13 CAL0002374 PMID: 12773383|CGD_REF: CAL0087974 heterozygous diploid, classical genetics (haploinsufficient phenotype assay) null CAI-4 viable heterozygous transposon insertion C. albicans orf19.5851 ORF STE13 CAL0002374 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.5851 ORF STE13 CAL0002374 PMID: 12773383|CGD_REF: CAL0087974 heterozygous diploid, classical genetics (haploinsufficient phenotype assay) null CAI-4 filamentous growth: increased solid Spider medium heterozygous transposon insertion C. albicans orf19.5851 ORF STE13 CAL0002374 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.5851 ORF STE13 CAL0002374 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.5851 ORF STE13 CAL0002374 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.5851 ORF STE13 CAL0002374 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.5855 ORF MBP1 CAL0002380 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.5855 ORF MBP1 CAL0002380 PMID: 21257795|CGD_REF: CAL0141410 homozygous diploid, classical genetics null mbp1::HIS1/mbp1::URA3 BWP17 viable C. albicans orf19.5855 ORF MBP1 CAL0002380 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.5855 ORF MBP1 CAL0002380 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.5855 ORF MBP1 CAL0002380 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.5855 ORF MBP1 CAL0002380 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.5859 ORF DAL8 CAL0002390 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.586 ORF ERV46 CAL0000341 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.586 ORF ERV46 CAL0000341 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 invasive growth: decreased solid SLAD media C. albicans orf19.5861 ORF KRE9 CAL0002403 PMID: 9707560|CGD_REF: CAL0081473 homozygous diploid, classical genetics null CAI-4 germ tube formation: absent serum-containing galactose medium C. albicans orf19.5861 ORF KRE9 CAL0002403 PMID: 9707560|CGD_REF: CAL0081473 heterozygous diploid, classical genetics null CAI-4 germ tube formation: normal serum-containing galactose medium C. albicans orf19.5861 ORF KRE9 CAL0002403 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.5861 ORF KRE9 CAL0002403 PMID: 9707560|CGD_REF: CAL0081473 heterozygous diploid, classical genetics null Not recorded viable C. albicans orf19.5861 ORF KRE9 CAL0002403 PMID: 9707560|CGD_REF: CAL0081473 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.5861 ORF KRE9 CAL0002403 PMID: 14507372|CGD_REF: CAL0088818 heterozygous diploid, large-scale survey (large-scale identification of essential genes by gene replacement and conditional expression (GRACE) method) repressible CAI-4 inviable one allele is deleted and the other is placed under repressible Tet promoter C. albicans orf19.5861 ORF KRE9 CAL0002403 PMID: 17873081|CGD_REF: CAL0118685 homozygous diploid, classical genetics null Not recorded inviable homozygous null mutant strain could not be recovered, suggesting that the gene is essential under the selection conditions C. albicans orf19.5861 ORF KRE9 CAL0002403 PMID: 9707560|CGD_REF: CAL0081473 homozygous diploid, classical genetics null Not recorded utilization of carbon source: decreased maltose C. albicans orf19.5861 ORF KRE9 CAL0002403 PMID: 9707560|CGD_REF: CAL0081473 homozygous diploid, classical genetics null Not recorded utilization of carbon source: absent D-glucose C. albicans orf19.5861 ORF KRE9 CAL0002403 PMID: 9707560|CGD_REF: CAL0081473 homozygous diploid, classical genetics null Not recorded utilization of carbon source: decreased glycerol C. albicans orf19.5861 ORF KRE9 CAL0002403 PMID: 9707560|CGD_REF: CAL0081473 homozygous diploid, classical genetics null Not recorded utilization of carbon source: decreased sucrose C. albicans orf19.5861 ORF KRE9 CAL0002403 PMID: 9707560|CGD_REF: CAL0081473 homozygous diploid, classical genetics null Not recorded chemical compound accumulation: decreased (1->6)-beta-D-glucan decreased cell wall beta-1,6-glucan C. albicans orf19.5861 ORF KRE9 CAL0002403 PMID: 9707560|CGD_REF: CAL0081473 homozygous diploid, classical genetics null Not recorded utilization of carbon source: decreased galactose C. albicans orf19.5861 ORF KRE9 CAL0002403 PMID: 9707560|CGD_REF: CAL0081473 homozygous diploid, classical genetics null Not recorded utilization of carbon source: decreased fructose C. albicans orf19.5861 ORF KRE9 CAL0002403 PMID: 9707560|CGD_REF: CAL0081473 homozygous diploid, classical genetics null Not recorded utilization of carbon source: decreased glucitol C. albicans orf19.5861 ORF KRE9 CAL0002403 PMID: 9707560|CGD_REF: CAL0081473 homozygous diploid, classical genetics null Not recorded utilization of carbon source: decreased mannose C. albicans orf19.5861 ORF KRE9 CAL0002403 PMID: 21135205|CGD_REF: CAL0139967 heterozygous diploid, competitive growth (large-scale identification of genes essential for virulence in mouse) repressible CAI-4 virulence: decreased mouse intravenous infection C. albicans orf19.5862 ORF AFP99 CAL0002404 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.5864 ORF URK1 CAL0002407 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.5866 ORF CAL0002411 PMID: 14663094|CGD_REF: CAL0080633 homozygous diploid, systematic mutation set (homozygous insertion mutants generated with URA3-ARG4-URA3 (UAU1) cassette) null BWP17 viable C. albicans orf19.5867 ORF WSC1 CAL0002412 PMID: 17555439|CGD_REF: CAL0117968 homozygous diploid, classical genetics null Not recorded survival rate in stationary phase: decreased C. albicans orf19.5867 ORF WSC1 CAL0002412 PMID: 17873081|CGD_REF: CAL0118685 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.5867 ORF WSC1 CAL0002412 PMID: 17873081|CGD_REF: CAL0118685 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased caspofungin C. albicans orf19.5867 ORF WSC1 CAL0002412 PMID: 20384695|CGD_REF: CAL0125373 homozygous diploid, classical genetics null BWP17 viable C. albicans orf19.5869 ORF CAL0002416 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.587 ORF CAL0000345 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.587 ORF CAL0000345 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.587 ORF CAL0000345 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: decreased rate liquid synthetic complete medium C. albicans orf19.587 ORF CAL0000345 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.5871 ORF SNF5 CAL0002429 PMID: 22359502|CGD_REF: CAL0000144048 homozygous diploid, classical genetics null BWP17 biofilm formation: decreased deletion mutant has a severe biofilm defect in vivo (rat central-venous-catheter infection model) C. albicans orf19.5871 ORF SNF5 CAL0002429 PMID: 22359502|CGD_REF: CAL0000144048 homozygous diploid, classical genetics null BWP17 biofilm formation: abnormal deletion mutant has a severe biofilm defect in vitro; sparse adherent cells and reduced biomass C. albicans orf19.5871 ORF SNF5 CAL0002429 PMID: 22359502|CGD_REF: CAL0000144048 homozygous diploid, classical genetics null BWP17 hyphal growth: abnormal hypha formation visualized after 4 hr of growth in Spider medium at 37 degrees C deletion mutant has a severe defect in hyphal morphogenesis C. albicans orf19.5871 ORF SNF5 CAL0002429 PMID: 22359502|CGD_REF: CAL0000144048 homozygous diploid, classical genetics null BWP17 viable insertion mutant, independent BWP17 deletion mutant and complemented strains also tested C. albicans orf19.5871 ORF SNF5 CAL0002429 PMID: 22359502|CGD_REF: CAL0000144048 homozygous diploid, classical genetics null BWP17 adhesion: decreased insertion mutant, independent BWP17 deletion mutant and complemented strains also tested C. albicans orf19.5871 ORF SNF5 CAL0002429 PMID: 22359502|CGD_REF: CAL0000144048 homozygous diploid, classical genetics null BWP17 resistance to chemicals: decreased Congo Red|caspofungin C. albicans orf19.5871 ORF SNF5 CAL0002429 PMID: 22359502|CGD_REF: CAL0000144048 homozygous diploid, classical genetics null BWP17 vegetative growth: abnormal mutants display increased cell aggregation during yeast form growth C. albicans orf19.5873 ORF POL1 CAL0002431 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.5873 ORF POL1 CAL0002431 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 invasive growth: decreased solid SLAD media C. albicans orf19.5874 ORF CAL0002433 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.5874 ORF CAL0002433 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.5874 ORF CAL0002433 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.5874 ORF CAL0002433 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.5874 ORF CAL0002433 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 invasive growth: decreased solid SLAD media C. albicans orf19.5875 ORF VAM3 CAL0002435 PMID: 19040629|CGD_REF: CAL0121263 heterozygous diploid, classical genetics repressible Not recorded vacuolar morphology: abnormal fragmented vacuoles in yeast-like cells C. albicans orf19.5875 ORF VAM3 CAL0002435 PMID: 19040629|CGD_REF: CAL0121263 heterozygous diploid, classical genetics repressible Not recorded vacuolar morphology: abnormal increased vacuole content in hyphae C. albicans orf19.5875 ORF VAM3 CAL0002435 PMID: 19040629|CGD_REF: CAL0121263 heterozygous diploid, classical genetics repressible CAI-4 hyphal growth: abnormal altered branching frequency in hyphae C. albicans orf19.5884 ORF CAL0002457 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.5885 ORF CAL0002459 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.5886 ORF CUP5 CAL0002461 PMID: 23913543|CGD_REF: CAL0000172635 heterozygous diploid, classical genetics repressible cup5::dpl200::99/tet-CUP5 Other C. albicans vegetative growth: decreased rate repressive conditions, doxycycline or tetracycline C. albicans orf19.5886 ORF CUP5 CAL0002461 PMID: 23913543|CGD_REF: CAL0000172635 heterozygous diploid, classical genetics repressible cup5::dpl200::99/tet-CUP5 Other C. albicans resistance to chemicals: decreased caspofungin repressive conditions, doxycycline or tetracycline C. albicans orf19.5886 ORF CUP5 CAL0002461 PMID: 23913543|CGD_REF: CAL0000172635 heterozygous diploid, classical genetics repressible cup5::dpl200::99/tet-CUP5 Other C. albicans cold sensitivity: increased repressive conditions, doxycycline or tetracycline C. albicans orf19.5886 ORF CUP5 CAL0002461 PMID: 23913543|CGD_REF: CAL0000172635 heterozygous diploid, classical genetics repressible cup5::dpl200::99/tet-CUP5 Other C. albicans chemical compound accumulation: decreased quinacrine repressive conditions, doxycycline or tetracycline C. albicans orf19.5886 ORF CUP5 CAL0002461 PMID: 23913543|CGD_REF: CAL0000172635 heterozygous diploid, classical genetics repressible cup5::dpl200::99/tet-CUP5 Other C. albicans vacuolar morphology: abnormal repressive conditions, doxycycline or tetracycline C. albicans orf19.5886 ORF CUP5 CAL0002461 PMID: 23913543|CGD_REF: CAL0000172635 heterozygous diploid, classical genetics repressible cup5::dpl200::99/tet-CUP5 Other C. albicans filamentous growth: decreased repressive conditions, doxycycline or tetracycline C. albicans orf19.5886 ORF CUP5 CAL0002461 PMID: 23913543|CGD_REF: CAL0000172635 heterozygous diploid, classical genetics repressible cup5::dpl200::99/tet-CUP5 Other C. albicans virulence: decreased repressive conditions, doxycycline or tetracycline in vitro model of infection (macrophage killing assay) C. albicans orf19.5886 ORF CUP5 CAL0002461 PMID: 23913543|CGD_REF: CAL0000172635 heterozygous diploid, classical genetics repressible cup5::dpl200::99/tet-CUP5 Other C. albicans protein secretion: decreased repressive conditions, doxycycline or tetracycline C. albicans orf19.5887 ORF NUP85 CAL0002462 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.5887 ORF NUP85 CAL0002462 PMID: 14663094|CGD_REF: CAL0080633 homozygous diploid, systematic mutation set (homozygous insertion mutants generated with URA3-ARG4-URA3 (UAU1) cassette) null BWP17 viable C. albicans orf19.5887 ORF NUP85 CAL0002462 PMID: 16087754|CGD_REF: CAL0114512 homozygous diploid, classical genetics null BWP17 hyphal growth: absent M199 pH 8 and Spider media C. albicans orf19.5887 ORF NUP85 CAL0002462 PMID: 16087754|CGD_REF: CAL0114512 homozygous diploid, classical genetics null BWP17 biofilm formation: decreased C. albicans orf19.5887 ORF NUP85 CAL0002462 PMID: 23856128|CGD_REF: CAL0000172540 homozygous diploid, classical genetics null BWP17 resistance to chemicals: decreased propolis C. albicans orf19.5887 ORF NUP85 CAL0002462 PMID: 16087754|CGD_REF: CAL0114512 homozygous diploid, classical genetics null nup85::Tn7-UAU1/nup85::Tn7-URA3 BWP17 biofilm formation: abnormal 60 h at 37 deg C in Spider medium or 60 h at 37 deg C in SD medium plus 50 mM glucose on silicone squares mutants form a 30-μm biofilm that includes yeast cells, pseudohyphae, and some rare hyphae C. albicans orf19.5887 ORF NUP85 CAL0002462 PMID: 16087754|CGD_REF: CAL0114512 homozygous diploid, classical genetics null nup85::Tn7-UAU1/nup85::Tn7-URA3 BWP17 hyphal growth: absent M199 medium, pH 8, at 37 deg C for 12 h -alkaline medium completely defective in alkaline-induced hyphal morphogenesis C. albicans orf19.589 ORF VPS21 CAL0000352 PMID: 19364843|CGD_REF: CAL0122751 homozygous diploid, classical genetics null Not recorded starvation resistance: decreased nitrogen starvation C. albicans orf19.589 ORF VPS21 CAL0000352 PMID: 19364843|CGD_REF: CAL0122751 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.589 ORF VPS21 CAL0000352 PMID: 19364843|CGD_REF: CAL0122751 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased rapamycin C. albicans orf19.589 ORF VPS21 CAL0000352 PMID: 19364843|CGD_REF: CAL0122751 homozygous diploid, classical genetics null Not recorded endocytosis: delayed delayed internalization of FM4-64 C. albicans orf19.589 ORF VPS21 CAL0000352 PMID: 19364843|CGD_REF: CAL0122751 homozygous diploid, classical genetics null CAI-4 filamentous growth: decreased C. albicans orf19.589 ORF VPS21 CAL0000352 PMID: 19364843|CGD_REF: CAL0122751 homozygous diploid, classical genetics null Not recorded virulence: decreased mouse intravenous infection C. albicans orf19.5892 ORF CAL0002471 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.5892 ORF CAL0002471 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.5892 ORF CAL0002471 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.5892 ORF CAL0002471 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.5892 ORF CAL0002471 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.5894 ORF CAL0002474 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.5901 ORF PKC1 CAL0003231 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.5901 ORF PKC1 CAL0003231 PMID: 14507372|CGD_REF: CAL0088818 heterozygous diploid, large-scale survey (large-scale identification of essential genes by gene replacement and conditional expression (GRACE) method) repressible CAI-4 viable one allele is deleted and the other is placed under repressible Tet promoter C. albicans orf19.5901 ORF PKC1 CAL0003231 PMID: 8813761|CGD_REF: CAL0081725 heterozygous diploid, classical genetics null Not recorded viable C. albicans orf19.5901 ORF PKC1 CAL0003231 PMID: 8813761|CGD_REF: CAL0081725 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.5901 ORF PKC1 CAL0003231 PMID: 16079350|CGD_REF: CAL0114435 homozygous diploid, classical genetics null Not recorded protein/peptide modification: abnormal defect in phosphorylation of Mkc1p in response to selective osmotic (hyper- or hypo-) or oxidative stress, cold, or cell wall disrupting agents Mkc1p C. albicans orf19.5901 ORF PKC1 CAL0003231 PMID: 8813761|CGD_REF: CAL0081725 heterozygous diploid, classical genetics null CAI-4 hyphal growth: normal liquid serum media C. albicans orf19.5901 ORF PKC1 CAL0003231 PMID: 8813761|CGD_REF: CAL0081725 homozygous diploid, classical genetics null CAI-4 hyphal growth: normal liquid serum media C. albicans orf19.5901 ORF PKC1 CAL0003231 PMID: 8813761|CGD_REF: CAL0081725 heterozygous diploid, classical genetics null Not recorded cell size: increased C. albicans orf19.5901 ORF PKC1 CAL0003231 PMID: 8813761|CGD_REF: CAL0081725 homozygous diploid, classical genetics null Not recorded osmotic stress resistance: decreased cells lyse even under hypertonic conditions C. albicans orf19.5901 ORF PKC1 CAL0003231 PMID: 16079350|CGD_REF: CAL0114435 homozygous diploid, classical genetics null Not recorded cold sensitivity: increased rescued by sorbitol C. albicans orf19.5901 ORF PKC1 CAL0003231 PMID: 8813761|CGD_REF: CAL0081725 homozygous diploid, classical genetics null Not recorded cytokinesis: decreased cells form chains and have elongated buds C. albicans orf19.5901 ORF PKC1 CAL0003231 PMID: 20140194|CGD_REF: CAL0124995 homozygous diploid, classical genetics null Other C. albicans resistance to chemicals: decreased caspofungin C. albicans orf19.5901 ORF PKC1 CAL0003231 PMID: 20865172|CGD_REF: CAL0126252 homozygous diploid, classical genetics null pkc1::FRT/pkc1::FRT SN95 resistance to chemicals: decreased fluconazole C. albicans orf19.5901 ORF PKC1 CAL0003231 PMID: 20865172|CGD_REF: CAL0126252 homozygous diploid, classical genetics null pkc1::FRT/pkc1::FRT SN95 resistance to chemicals: decreased fenpropimorph C. albicans orf19.5901 ORF PKC1 CAL0003231 PMID: 20865172|CGD_REF: CAL0126252 homozygous diploid, classical genetics null pkc1::FRT/pkc1::FRT SN95 resistance to chemicals: decreased terbinafine C. albicans orf19.5901 ORF PKC1 CAL0003231 PMID: 20865172|CGD_REF: CAL0126252 homozygous diploid, classical genetics null pkc1::FRT/pkc1::FRT SN95 virulence: decreased mouse intravenous infection C. albicans orf19.5901 ORF PKC1 CAL0003231 PMID: 20140194|CGD_REF: CAL0124995 homozygous diploid, classical genetics null Other C. albicans viable C. albicans orf19.5902 ORF RAS2 CAL0003232 PMID: 19788542|CGD_REF: CAL0124303 homozygous diploid, classical genetics null Not recorded metal resistance: increased cobalt(2+) C. albicans orf19.5902 ORF RAS2 CAL0003232 PMID: 19788542|CGD_REF: CAL0124303 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased hydrogen peroxide C. albicans orf19.5902 ORF RAS2 CAL0003232 PMID: 12773383|CGD_REF: CAL0087974 heterozygous diploid, classical genetics (haploinsufficient phenotype assay) unspecified CAI-4 filamentous growth: decreased solid Spider medium transposon insertion proximal to, but not within, the ORF C. albicans orf19.5903 ORF RAX1 CAL0003233 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.5903 ORF RAX1 CAL0003233 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.5903 ORF RAX1 CAL0003233 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.5903 ORF RAX1 CAL0003233 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.5903 ORF RAX1 CAL0003233 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.5904 ORF RPL19A CAL0003235 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.5905 ORF CAL0003238 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.5906 ORF ADE2 CAL0003241 PMID: 11254618|CGD_REF: CAL0080681 heterozygous diploid, classical genetics null Not recorded vegetative growth: decreased rate in the absence of supplemental adenine C. albicans orf19.5906 ORF ADE2 CAL0003241 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.5906 ORF ADE2 CAL0003241 PMID: 10074081|CGD_REF: CAL0080678 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.5906 ORF ADE2 CAL0003241 PMID: 11254618|CGD_REF: CAL0080681 heterozygous diploid, classical genetics null Not recorded viable C. albicans orf19.5906 ORF ADE2 CAL0003241 PMID: 11254618|CGD_REF: CAL0080681 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.5906 ORF ADE2 CAL0003241 PMID: 16043373|CGD_REF: CAL0114589 heterozygous diploid, classical genetics null Not recorded viable C. albicans orf19.5906 ORF ADE2 CAL0003241 PMID: 16043373|CGD_REF: CAL0114589 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.5906 ORF ADE2 CAL0003241 PMID: 8349105|CGD_REF: CAL0082009 heterozygous diploid, classical genetics null Not recorded viable C. albicans orf19.5906 ORF ADE2 CAL0003241 PMID: 8349105|CGD_REF: CAL0082009 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.5906 ORF ADE2 CAL0003241 PMID: 10074081|CGD_REF: CAL0080678 homozygous diploid, classical genetics null Not recorded auxotrophy adenine C. albicans orf19.5906 ORF ADE2 CAL0003241 PMID: 11254618|CGD_REF: CAL0080681 homozygous diploid, classical genetics null Not recorded auxotrophy adenine C. albicans orf19.5906 ORF ADE2 CAL0003241 PMID: 11254618|CGD_REF: CAL0080681 homozygous diploid, classical genetics null Not recorded auxotrophy adenine C. albicans orf19.5906 ORF ADE2 CAL0003241 PMID: 1879944|CGD_REF: CAL0091438 homozygous diploid, classical genetics null Not recorded auxotrophy adenine C. albicans orf19.5906 ORF ADE2 CAL0003241 PMID: 8349105|CGD_REF: CAL0082009 homozygous diploid, classical genetics null Not recorded auxotrophy adenine C. albicans orf19.5906 ORF ADE2 CAL0003241 PMID: 10074081|CGD_REF: CAL0080678 homozygous diploid, classical genetics null Not recorded colony color: abnormal colonies are red C. albicans orf19.5906 ORF ADE2 CAL0003241 PMID: 11254618|CGD_REF: CAL0080681 homozygous diploid, classical genetics null Not recorded colony color: abnormal colonies are red C. albicans orf19.5906 ORF ADE2 CAL0003241 PMID: 16043373|CGD_REF: CAL0114589 homozygous diploid, classical genetics null Not recorded colony color: abnormal red colonies C. albicans orf19.5906 ORF ADE2 CAL0003241 PMID: 6358187|CGD_REF: CAL0080660 unknown ploidy, classical genetics unspecified Other C. albicans auxotrophy adenine C. albicans orf19.5906 ORF ADE2 CAL0003241 PMID: 6358187|CGD_REF: CAL0080660 unknown ploidy, classical genetics unspecified Other C. albicans colony color: abnormal colonies are red C. albicans orf19.5906 ORF ADE2 CAL0003241 PMID: 6358187|CGD_REF: CAL0080660 unknown ploidy, classical genetics unspecified Other C. albicans viable C. albicans orf19.5906 ORF ADE2 CAL0003241 PMID: 1347636|CGD_REF: CAL0080664 unknown ploidy, classical genetics unspecified Other C. albicans colony color: abnormal aneuploid strain with a single copy of the chromosome bearing an ade2 mutation makes small red colonies, and homozygous ade2 mutant with both homologous chromosomes makes large red colonies C. albicans orf19.5906 ORF ADE2 CAL0003241 PMID: 11254618|CGD_REF: CAL0080681 homozygous diploid, classical genetics null Not recorded virulence: decreased immunosuppressed mouse intravenous infection C. albicans orf19.5906 ORF ADE2 CAL0003241 PMID: 11254618|CGD_REF: CAL0080681 heterozygous diploid, classical genetics null Not recorded virulence: normal immunosuppressed mouse intravenous infection C. albicans orf19.5906 ORF ADE2 CAL0003241 PMID: 1879944|CGD_REF: CAL0091438 homozygous diploid, classical genetics null Not recorded virulence: decreased immunosuppressed mouse intravenous infection C. albicans orf19.5906 ORF ADE2 CAL0003241 PMID: 1879944|CGD_REF: CAL0091438 homozygous diploid, classical genetics null Not recorded virulence: decreased mouse intravenous infection C. albicans orf19.5906 ORF ADE2 CAL0003241 PMID: 21135205|CGD_REF: CAL0139967 heterozygous diploid, competitive growth (large-scale identification of genes essential for virulence in mouse) repressible CAI-4 virulence: decreased mouse intravenous infection C. albicans orf19.5908 ORF TEC1 CAL0003246 PMID: 15755921|CGD_REF: CAL0082335 homozygous diploid, classical genetics null BWP17 germ tube formation: absent serum-containing medium C. albicans orf19.5908 ORF TEC1 CAL0003246 PMID: 15964282|CGD_REF: CAL0114274 homozygous diploid, systematic mutation set (split-marker transposon insertion strategy to disrupt both alleles) null BWP17 viable C. albicans orf19.5908 ORF TEC1 CAL0003246 PMID: 11069668|CGD_REF: CAL0081307 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.5908 ORF TEC1 CAL0003246 PMID: 11533231|CGD_REF: CAL0080743 heterozygous diploid, classical genetics overexpression Not recorded viable C. albicans orf19.5908 ORF TEC1 CAL0003246 PMID: 15964282|CGD_REF: CAL0114274 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.5908 ORF TEC1 CAL0003246 PMID: 19463063|CGD_REF: CAL0123630 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.5908 ORF TEC1 CAL0003246 PMID: 15039365|CGD_REF: CAL0081880 homozygous diploid, classical genetics null Other C. albicans hyphal growth: normal growth in mouse kidney mouse intravenous infection C. albicans orf19.5908 ORF TEC1 CAL0003246 PMID: 15039365|CGD_REF: CAL0081880 homozygous diploid, classical genetics null Other C. albicans hyphal growth: decreased growth in mouse liver mouse peritoneal infection C. albicans orf19.5908 ORF TEC1 CAL0003246 PMID: 15964282|CGD_REF: CAL0114274 homozygous diploid, classical genetics null BWP17 hyphal growth: abnormal mutant cells exhibit a defect in hyphal formation in mixed biofilms composed of wild-type and mutant cells C. albicans orf19.5908 ORF TEC1 CAL0003246 PMID: 11069668|CGD_REF: CAL0081307 homozygous diploid, classical genetics null Not recorded hyphal growth: absent liquid serum-containing medium, Lee's medium at neutral pH, or within macrophages C. albicans orf19.5908 ORF TEC1 CAL0003246 PMID: 11533231|CGD_REF: CAL0080743 heterozygous diploid, classical genetics overexpression Not recorded hyphal growth: increased solid SSA medium C. albicans orf19.5908 ORF TEC1 CAL0003246 PMID: 11595734|CGD_REF: CAL0081060 heterozygous diploid, classical genetics overexpression Not recorded hyphal growth: increased solid SSA medium C. albicans orf19.5908 ORF TEC1 CAL0003246 PMID: 15964282|CGD_REF: CAL0114274 homozygous diploid, systematic mutation set (split-marker transposon insertion strategy to disrupt both alleles) null BWP17 biofilm formation: decreased produces a rudimentary biofilm less than 20 um deep on a silicone substrate in vitro C. albicans orf19.5908 ORF TEC1 CAL0003246 PMID: 15964282|CGD_REF: CAL0114274 heterozygous diploid, classical genetics null BWP17 biofilm formation: normal heterozygous null mutant reconstituted by transformation of the homozygous null with the wild-type gene C. albicans orf19.5908 ORF TEC1 CAL0003246 PMID: 20041210|CGD_REF: CAL0124764 homozygous diploid, systematic mutation set null SN152 colony appearance: abnormal YEPD medium at 42 deg C strongly decreased colony fuzziness and/or peripheral filamentation C. albicans orf19.5908 ORF TEC1 CAL0003246 PMID: 20041210|CGD_REF: CAL0124764 homozygous diploid, systematic mutation set null SN152 colony appearance: abnormal Lee's medium pH 6.8 at 37 deg C strongly decreased colony fuzziness and/or peripheral filamentation C. albicans orf19.5908 ORF TEC1 CAL0003246 PMID: 19115836|CGD_REF: CAL0122036 heterozygous diploid, competitive growth (haploinsufficient phenotype assay, barcode deletion set) null SC5314 resistance to chemicals: increased virgineone C. albicans orf19.5908 ORF TEC1 CAL0003246 PMID: 21407800|CGD_REF: CAL0141800 homozygous diploid, classical genetics null BWP17 interaction with host/environment: abnormal significantly reduces adhesion, invasion, and damage to epithelial cells ex vivo model of infection C. albicans orf19.5908 ORF TEC1 CAL0003246 PMID: 22265407|CGD_REF: CAL0000143925 homozygous diploid, classical genetics null Other C. albicans biofilm formation: decreased C. albicans orf19.5908 ORF TEC1 CAL0003246 PMID: 22276126|CGD_REF: CAL0000143926 aneuploid, classical genetics overexpression Other C. albicans filamentous growth: increased C. albicans orf19.5908 ORF TEC1 CAL0003246 PMID: 16839200|CGD_REF: CAL0116292 homozygous diploid, classical genetics null BWP17 biofilm formation: abnormal C. albicans orf19.5908 ORF TEC1 CAL0003246 PMID: 22923045|CGD_REF: CAL0000157829 homozygous diploid, competitive growth null Other C. albicans formation of anatomical structure: absent elevated concentrations of CO2 at 37 deg finger structure C. albicans orf19.5908 ORF TEC1 CAL0003246 PMID: 23637598|CGD_REF: CAL0000172002 homozygous diploid, classical genetics null a/alpha arg1::hisG/arg1::hisG tec1::HIS1/tec1::LEU2 SC5314 biofilm formation: decreased 37 degrees C in Spider medium C. albicans orf19.5908 ORF TEC1 CAL0003246 PMID: 23637598|CGD_REF: CAL0000172002 homozygous diploid, classical genetics null a/a tec1/tec1::SAT P37005 biofilm formation: decreased 37 degrees C in Spider medium deficient in 10uM alpha pheromone stimulated biofilms C. albicans orf19.5908 ORF TEC1 CAL0003246 PMID: 19463063|CGD_REF: CAL0123630 homozygous diploid, systematic mutation set (split-marker transposon insertion strategy to disrupt both alleles) null BWP17 virulence: normal Toll mutant D. melanogaster invasive infection insect infection C. albicans orf19.5908 ORF TEC1 CAL0003246 PMID: 11069668|CGD_REF: CAL0081307 homozygous diploid, classical genetics null Not recorded virulence: absent mouse intravenous infection C. albicans orf19.5908 ORF TEC1 CAL0003246 PMID: 15039365|CGD_REF: CAL0081880 homozygous diploid, classical genetics null Not recorded virulence: decreased decreased liver tissue invasiveness mouse peritoneal infection C. albicans orf19.5908 ORF TEC1 CAL0003246 PMID: 20223293|CGD_REF: CAL0125139 homozygous diploid, classical genetics null BWP17 virulence: decreased G. mellonella infection insect infection C. albicans orf19.5908 ORF TEC1 CAL0003246 PMID: 20454615|CGD_REF: CAL0125454 homozygous diploid, classical genetics null tec1::FRT/tec1::FRT P37005 adhesion: decreased white cells in the presence of alpha pheromone C. albicans orf19.5908 ORF TEC1 CAL0003246 PMID: 20454615|CGD_REF: CAL0125454 homozygous diploid, classical genetics null tec1::FRT/tec1::FRT P37005 biofilm formation: abnormal white cells in the presence of alpha pheromone decreased thickness in the absence of minority opaque cell and decreased enhancement of white cell biofilm formation in the presence of minority opaque cellss C. albicans orf19.5908 ORF TEC1 CAL0003246 PMID: 20435697|CGD_REF: CAL0125740 homozygous diploid, classical genetics null SC5314 RNA accumulation: decreased mouse cecum expression of ECE1 20-fold lower than in wild-type cells ECE1 mRNA mouse gastrointestinal tract infection C. albicans orf19.5910 ORF CAL0003263 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.5911 ORF CMK1 CAL0003264 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.5911 ORF CMK1 CAL0003264 PMID: 24661877|CGD_REF: CAL0000173817 homozygous diploid, classical genetics null BWP17 viable C. albicans orf19.5911 ORF CMK1 CAL0003264 PMID: 24661877|CGD_REF: CAL0000173817 homozygous diploid, classical genetics null BWP17 resistance to chemicals: decreased Calcofluor White C. albicans orf19.5912 ORF MAK21 CAL0003265 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, competitive growth (haploinsufficient phenotype assay, barcode deletion set) null SC5314 resistance to chemicals: decreased tubercidin C. albicans orf19.5912 ORF MAK21 CAL0003265 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.5915 ORF DUR35 CAL0003269 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.5915 ORF DUR35 CAL0003269 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.5915 ORF DUR35 CAL0003269 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.5915 ORF DUR35 CAL0003269 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.5915 ORF DUR35 CAL0003269 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.5917 ORF STP1 CAL0003274 PMID: 16227594|CGD_REF: CAL0114869 homozygous diploid, classical genetics null Not recorded utilization of nitrogen source: absent protein as sole nitrogen source C. albicans orf19.5917 ORF STP1 CAL0003274 PMID: 16227594|CGD_REF: CAL0114869 heterozygous diploid, classical genetics null Not recorded viable C. albicans orf19.5917 ORF STP1 CAL0003274 PMID: 16227594|CGD_REF: CAL0114869 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.5917 ORF STP1 CAL0003274 PMID: 20041210|CGD_REF: CAL0124764 homozygous diploid, systematic mutation set null SN152 resistance to chemicals: increased rapamycin strongly resistant C. albicans orf19.5917 ORF STP1 CAL0003274 PMID: 16227594|CGD_REF: CAL0114869 homozygous diploid, classical genetics null Not recorded protein secretion: decreased YCB/BSA media decreased secreted aspartyl protease activity C. albicans orf19.5917 ORF STP1 CAL0003274 PMID: 20041210|CGD_REF: CAL0124764 homozygous diploid, systematic mutation set null SN152 resistance to chemicals: increased caffeine strongly resistant C. albicans orf19.5918 ORF CAL0003278 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 invasive growth: decreased solid SLAD media C. albicans orf19.5919 ORF MEA1 CAL0003282 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.5919 ORF MEA1 CAL0003282 PMID: 17715368|CGD_REF: CAL0118559 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.5920 ORF CAL0003296 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient YNB medium C. albicans orf19.5921 ORF CAL0003297 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.5924 ORF ZCF31 CAL0003299 PMID: 20041210|CGD_REF: CAL0124764 homozygous diploid, systematic mutation set null SN152 resistance to chemicals: increased Calcofluor White strongly resistant C. albicans orf19.5924 ORF ZCF31 CAL0003299 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.5924 ORF ZCF31 CAL0003299 PMID: 20041210|CGD_REF: CAL0124764 homozygous diploid, systematic mutation set null SN152 resistance to chemicals: decreased sodium dodecyl sulfate severely sensitive C. albicans orf19.5924 ORF ZCF31 CAL0003299 PMID: 20041210|CGD_REF: CAL0124764 homozygous diploid, systematic mutation set null SN152 metal resistance: decreased copper(2+) strongly sensitive C. albicans orf19.5924 ORF ZCF31 CAL0003299 PMID: 22359502|CGD_REF: CAL0000144048 homozygous diploid, classical genetics null BWP17 viable insertion mutant, independent SN152 deletion mutant strain also tested C. albicans orf19.5924 ORF ZCF31 CAL0003299 PMID: 22359502|CGD_REF: CAL0000144048 homozygous diploid, classical genetics null BWP17 adhesion: decreased insertion mutant, independent SN152 deletion mutant strain also tested C. albicans orf19.5925 ORF CAL0003301 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.5927 ORF RPS15 CAL0003305 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient SC medium C. albicans orf19.5927 ORF RPS15 CAL0003305 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient YNB medium C. albicans orf19.5927 ORF RPS15 CAL0003305 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient SLAD medium C. albicans orf19.593 ORF FGR32 CAL0000368 PMID: 12773383|CGD_REF: CAL0087974 heterozygous diploid, classical genetics (haploinsufficient phenotype assay) null CAI-4 viable heterozygous deletion C. albicans orf19.593 ORF FGR32 CAL0000368 PMID: 12773383|CGD_REF: CAL0087974 heterozygous diploid, classical genetics (haploinsufficient phenotype assay) null CAI-4 filamentous growth: increased solid Spider medium heterozygous deletion C. albicans orf19.593 ORF FGR32 CAL0000368 PMID: 12773383|CGD_REF: CAL0087974 heterozygous diploid, classical genetics (haploinsufficient phenotype assay) null CAI-4 filamentous growth: decreased solid YEPD plus serum heterozygous deletion C. albicans orf19.593 ORF FGR32 CAL0000368 PMID: 12773383|CGD_REF: CAL0087974 heterozygous diploid, classical genetics (haploinsufficient phenotype assay) unspecified CAI-4 filamentous growth: increased solid YEPD plus serum heterozygous transposon insertion C. albicans orf19.5931 ORF ARV1 CAL0003325 PMID: 22142782|CGD_REF: CAL0000143700 homozygous diploid, classical genetics null BWP17 resistance to chemicals: decreased terbinafine C. albicans orf19.5931 ORF ARV1 CAL0003325 PMID: 22142782|CGD_REF: CAL0000143700 homozygous diploid, classical genetics null BWP17 viable C. albicans orf19.5931 ORF ARV1 CAL0003325 PMID: 22142782|CGD_REF: CAL0000143700 homozygous diploid, classical genetics null BWP17 resistance to chemicals: decreased itraconazole C. albicans orf19.5931 ORF ARV1 CAL0003325 PMID: 22142782|CGD_REF: CAL0000143700 homozygous diploid, classical genetics null BWP17 resistance to chemicals: decreased nystatin C. albicans orf19.5931 ORF ARV1 CAL0003325 PMID: 22142782|CGD_REF: CAL0000143700 homozygous diploid, classical genetics null BWP17 virulence: absent mouse intravenous infection C. albicans orf19.5932 ORF CAL0003326 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.5934 ORF CAL0003329 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.5938 ORF SEN1 CAL0003335 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.5940 ORF ZCF32 CAL0003346 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.5940 ORF ZCF32 CAL0003346 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.5940 ORF ZCF32 CAL0003346 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.5940 ORF ZCF32 CAL0003346 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.5941 ORF CAL0003347 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.5942 ORF CAL0003348 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.5942 ORF CAL0003348 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.5942 ORF CAL0003348 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.5942 ORF CAL0003348 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.5942 ORF CAL0003348 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.5947 ORF SEC7 CAL0003353 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, competitive growth (haploinsufficient phenotype assay, barcode deletion set) null SC5314 resistance to chemicals: decreased brefeldin A C. albicans orf19.5947 ORF SEC7 CAL0003353 PMID: 19623926|CGD_REF: CAL0124054 heterozygous diploid, competitive growth (haploinsufficient phenotype assay, barcode deletion set) null SC5314 resistance to chemicals: decreased brefeldin A C. albicans orf19.5947 ORF SEC7 CAL0003353 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.5949 ORF FAS2 CAL0003358 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.5949 ORF FAS2 CAL0003358 PMID: 9009352|CGD_REF: CAL0081282 heterozygous diploid, classical genetics null Not recorded viable wild-type growth rate C. albicans orf19.5949 ORF FAS2 CAL0003358 PMID: 8828218|CGD_REF: CAL0081281 heterozygous diploid, classical genetics null Not recorded viable C. albicans orf19.5949 ORF FAS2 CAL0003358 PMID: 8828218|CGD_REF: CAL0081281 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.5949 ORF FAS2 CAL0003358 PMID: 9009352|CGD_REF: CAL0081282 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.5949 ORF FAS2 CAL0003358 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, competitive growth (haploinsufficient phenotype assay, barcode deletion set) null SC5314 resistance to chemicals: normal cerulenin C. albicans orf19.5949 ORF FAS2 CAL0003358 PMID: 8828218|CGD_REF: CAL0081281 homozygous diploid, classical genetics null Not recorded auxotrophy fatty acid C. albicans orf19.5949 ORF FAS2 CAL0003358 PMID: 9009352|CGD_REF: CAL0081282 homozygous diploid, classical genetics null Not recorded auxotrophy fatty acid C. albicans orf19.5949 ORF FAS2 CAL0003358 PMID: 9009352|CGD_REF: CAL0081282 homozygous diploid, classical genetics null Not recorded virulence: absent mouse intravenous infection C. albicans orf19.5949 ORF FAS2 CAL0003358 PMID: 9009352|CGD_REF: CAL0081282 heterozygous diploid, classical genetics null Not recorded virulence: decreased mouse intravenous infection C. albicans orf19.5949 ORF FAS2 CAL0003358 PMID: 8828218|CGD_REF: CAL0081281 heterozygous diploid, classical genetics null Not recorded virulence: decreased virulence is intermediate between that of the homozygous null mutant and wild type rat oropharyngeal infection C. albicans orf19.5949 ORF FAS2 CAL0003358 PMID: 8828218|CGD_REF: CAL0081281 homozygous diploid, classical genetics null Not recorded virulence: absent rat oropharyngeal infection C. albicans orf19.5949 ORF FAS2 CAL0003358 PMID: 21135205|CGD_REF: CAL0139967 heterozygous diploid, large-scale survey (large-scale identification of genes essential for virulence in mouse) repressible CAI-4 virulence: absent mouse intravenous infection C. albicans orf19.5953 ORF CAL0003373 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.5956 ORF PIN3 CAL0003378 PMID: 20402797|CGD_REF: CAL0125391 homozygous diploid, classical genetics null Other C. albicans viable C. albicans orf19.5958 ORF CDR2 CAL0003382 PMID: 19223631|CGD_REF: CAL0122395 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased ketoconazole slight decrease C. albicans orf19.5958 ORF CDR2 CAL0003382 PMID: 19223631|CGD_REF: CAL0122395 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased itraconazole slight decrease C. albicans orf19.5958 ORF CDR2 CAL0003382 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.5958 ORF CDR2 CAL0003382 PMID: 9043118|CGD_REF: CAL0080888 homozygous diploid, classical genetics null Not recorded viable no apparent phenotype C. albicans orf19.5958 ORF CDR2 CAL0003382 PMID: 12657057|CGD_REF: CAL0080947 heterozygous diploid, classical genetics overexpression Not recorded resistance to chemicals: increased caspofungin C. albicans orf19.5958 ORF CDR2 CAL0003382 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, competitive growth (haploinsufficient phenotype assay, barcode deletion set) null SC5314 resistance to chemicals: decreased dyclonine C. albicans orf19.5958 ORF CDR2 CAL0003382 PMID: 9756759|CGD_REF: CAL0080905 heterozygous diploid, classical genetics overexpression Not recorded resistance to chemicals: increased triazoles C. albicans orf19.5958 ORF CDR2 CAL0003382 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, competitive growth (haploinsufficient phenotype assay, barcode deletion set) null SC5314 resistance to chemicals: normal fluconazole C. albicans orf19.5958 ORF CDR2 CAL0003382 PMID: 19223631|CGD_REF: CAL0122395 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased fluconazole slight decrease C. albicans orf19.5959 ORF NOP14 CAL0003384 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, competitive growth (haploinsufficient phenotype assay, barcode deletion set) null SC5314 resistance to chemicals: increased 5-fluorouracil C. albicans orf19.5959 ORF NOP14 CAL0003384 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, competitive growth (haploinsufficient phenotype assay, barcode deletion set) null SC5314 resistance to chemicals: increased tubercidin C. albicans orf19.5959 ORF NOP14 CAL0003384 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, competitive growth (haploinsufficient phenotype assay, barcode deletion set) null SC5314 resistance to chemicals: increased flucytosine C. albicans orf19.5959 ORF NOP14 CAL0003384 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.5959 ORF NOP14 CAL0003384 PMID: 19623926|CGD_REF: CAL0124054 heterozygous diploid, competitive growth (haploinsufficient phenotype assay, barcode deletion set) null SC5314 resistance to chemicals: increased parnafungin C. albicans orf19.5959 ORF NOP14 CAL0003384 PMID: 21135205|CGD_REF: CAL0139967 heterozygous diploid, competitive growth (large-scale identification of genes essential for virulence in mouse) repressible CAI-4 virulence: decreased mouse intravenous infection C. albicans orf19.596.1 ORF NOP10 CAF0006902 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.596.1 ORF NOP10 CAF0006902 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient YPD medium C. albicans orf19.596.1 ORF NOP10 CAF0006902 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient SC medium C. albicans orf19.5960 ORF NCE102 CAL0003396 PMID: 24281718|CGD_REF: CAL0000173710 homozygous diploid, classical genetics null BWP17 actin cytoskeleton morphology: abnormal C. albicans orf19.5960 ORF NCE102 CAL0003396 PMID: 24281718|CGD_REF: CAL0000173710 homozygous diploid, classical genetics null BWP17 viable C. albicans orf19.5960 ORF NCE102 CAL0003396 PMID: 24281718|CGD_REF: CAL0000173710 homozygous diploid, classical genetics null BWP17 invasive growth: decreased agar concentrations below 2% no defect in denser agar (4% and higher) C. albicans orf19.5960 ORF NCE102 CAL0003396 PMID: 24281718|CGD_REF: CAL0000173710 homozygous diploid, classical genetics null BWP17 hyphal growth: decreased C. albicans orf19.5960 ORF NCE102 CAL0003396 PMID: 24281718|CGD_REF: CAL0000173710 homozygous diploid, classical genetics null BWP17 virulence: decreased mouse intravenous infection C. albicans orf19.5961 ORF CAL0003397 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.5962 ORF HGT4 CAL0003398 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.5962 ORF HGT4 CAL0003398 PMID: 17030998|CGD_REF: CAL0116776 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.5962 ORF HGT4 CAL0003398 PMID: 17030998|CGD_REF: CAL0116776 heterozygous diploid, classical genetics activation SNF3-(HGT4-1) (R167K) Not recorded viable C. albicans orf19.5962 ORF HGT4 CAL0003398 PMID: 17030998|CGD_REF: CAL0116776 homozygous diploid, classical genetics null Not recorded utilization of carbon source: decreased D-glucose in the presence of Antimycin A C. albicans orf19.5962 ORF HGT4 CAL0003398 PMID: 17030998|CGD_REF: CAL0116776 homozygous diploid, classical genetics null Not recorded utilization of carbon source: decreased D-glucose C. albicans orf19.5962 ORF HGT4 CAL0003398 PMID: 19249212|CGD_REF: CAL0122456 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased antimycin A C. albicans orf19.5962 ORF HGT4 CAL0003398 PMID: 17030998|CGD_REF: CAL0116776 homozygous diploid, classical genetics null Not recorded utilization of carbon source: decreased fructose C. albicans orf19.5962 ORF HGT4 CAL0003398 PMID: 17030998|CGD_REF: CAL0116776 heterozygous diploid, classical genetics null BWP17 filamentous growth: normal reconstituted heterozygote C. albicans orf19.5962 ORF HGT4 CAL0003398 PMID: 17030998|CGD_REF: CAL0116776 heterozygous diploid, classical genetics activation BWP17 filamentous growth: normal serum-containing medium C. albicans orf19.5962 ORF HGT4 CAL0003398 PMID: 17030998|CGD_REF: CAL0116776 homozygous diploid, classical genetics null BWP17 filamentous growth: normal serum-containing medium C. albicans orf19.5962 ORF HGT4 CAL0003398 PMID: 17030998|CGD_REF: CAL0116776 homozygous diploid, classical genetics null BWP17 filamentous growth: decreased solid Spider medium C. albicans orf19.5962 ORF HGT4 CAL0003398 PMID: 17030998|CGD_REF: CAL0116776 heterozygous diploid, classical genetics activation BWP17 filamentous growth: increased solid Spider medium C. albicans orf19.5962 ORF HGT4 CAL0003398 PMID: 19249212|CGD_REF: CAL0122456 homozygous diploid, classical genetics null BWP17 filamentous growth: decreased galactose carbon source C. albicans orf19.5962 ORF HGT4 CAL0003398 PMID: 17030998|CGD_REF: CAL0116776 homozygous diploid, classical genetics null Not recorded utilization of carbon source: decreased mannose C. albicans orf19.5962 ORF HGT4 CAL0003398 PMID: 17030998|CGD_REF: CAL0116776 homozygous diploid, classical genetics null Not recorded virulence: decreased exhibits normal kidney colonization mouse intravenous infection C. albicans orf19.5962 ORF HGT4 CAL0003398 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 invasive growth: decreased solid SLAD media C. albicans orf19.5963 ORF CAL0003399 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.5964 ORF ARF2 CAL0003401 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, competitive growth (haploinsufficient phenotype assay, barcode deletion set) null SC5314 resistance to chemicals: decreased brefeldin A C. albicans orf19.5964 ORF ARF2 CAL0003401 PMID: 19623926|CGD_REF: CAL0124054 heterozygous diploid, competitive growth (haploinsufficient phenotype assay, barcode deletion set) null SC5314 resistance to chemicals: decreased brefeldin A C. albicans orf19.5964 ORF ARF2 CAL0003401 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.5965 ORF CAL0003403 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.5965 ORF CAL0003403 PMID: 20494978|CGD_REF: CAL0125636 heterozygous diploid, classical genetics null BWP17 resistance to chemicals: decreased clotrimazole (75 uM) growth in liquid culture confirmation of mutant phenotypes for heterozygous transposon insertion strains showing sensitivity in a large-scale assay C. albicans orf19.5967 ORF FGR44 CAL0003407 PMID: 12773383|CGD_REF: CAL0087974 heterozygous diploid, classical genetics (haploinsufficient phenotype assay) null CAI-4 viable heterozygous transposon insertion C. albicans orf19.5968 ORF RDI1 CAL0003409 PMID: 12773383|CGD_REF: CAL0087974 heterozygous diploid, classical genetics (haploinsufficient phenotype assay) null CAI-4 viable heterozygous deletion or transposon insertion C. albicans orf19.5968 ORF RDI1 CAL0003409 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.5968 ORF RDI1 CAL0003409 PMID: 17093060|CGD_REF: CAL0117112 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.5968 ORF RDI1 CAL0003409 PMID: 12773383|CGD_REF: CAL0087974 heterozygous diploid, classical genetics (haploinsufficient phenotype assay) null CAI-4 filamentous growth: increased solid Spider medium or solid YEPD plus serum heterozygous deletion or transposon insertion C. albicans orf19.5968 ORF RDI1 CAL0003409 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.5968 ORF RDI1 CAL0003409 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: abnormal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.5968 ORF RDI1 CAL0003409 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.5968 ORF RDI1 CAL0003409 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.5970 ORF CAL0003422 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.5971 ORF CAL0003423 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.5971 ORF CAL0003423 PMID: 20494978|CGD_REF: CAL0125636 heterozygous diploid, classical genetics null BWP17 resistance to chemicals: decreased clotrimazole (75 uM) growth in liquid culture confirmation of mutant phenotypes for heterozygous transposon insertion strains showing sensitivity in a large-scale assay C. albicans orf19.5973 ORF PHB2 CAL0003424 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.5974 ORF ATG9 CAL0003426 PMID: 17185534|CGD_REF: CAL0117104 homozygous diploid, classical genetics null Not recorded starvation resistance: decreased nitrogen starvation C. albicans orf19.5974 ORF ATG9 CAL0003426 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.5974 ORF ATG9 CAL0003426 PMID: 17185534|CGD_REF: CAL0117104 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.5974 ORF ATG9 CAL0003426 PMID: 17185534|CGD_REF: CAL0117104 homozygous diploid, classical genetics null Not recorded protein transport: abnormal reporter is not delivered to vacuole by cytoplasm to vacuole trafficking Lap41p-GFP C. albicans orf19.5974 ORF ATG9 CAL0003426 PMID: 17185534|CGD_REF: CAL0117104 homozygous diploid, classical genetics null Not recorded autophagy: abnormal nitrogen starvation in the presence of PMSF fails to accumulate autophagic bodies C. albicans orf19.5975 ORF TRY4 CAL0003428 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.5975 ORF TRY4 CAL0003428 PMID: 15964282|CGD_REF: CAL0114274 homozygous diploid, systematic mutation set (split-marker transposon insertion strategy to disrupt both alleles) null BWP17 viable C. albicans orf19.5975 ORF TRY4 CAL0003428 PMID: 15964282|CGD_REF: CAL0114274 homozygous diploid, systematic mutation set (split-marker transposon insertion strategy to disrupt both alleles) null BWP17 biofilm formation: normal C. albicans orf19.5975 ORF TRY4 CAL0003428 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.5975 ORF TRY4 CAL0003428 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.5975 ORF TRY4 CAL0003428 PMID: 22359502|CGD_REF: CAL0000144048 homozygous diploid, classical genetics null BWP17 viable insertion mutant, independent SN152 deletion mutant strain also tested C. albicans orf19.5975 ORF TRY4 CAL0003428 PMID: 22359502|CGD_REF: CAL0000144048 homozygous diploid, classical genetics null BWP17 adhesion: decreased insertion mutant, independent SN152 deletion mutant strain also tested C. albicans orf19.5975 ORF TRY4 CAL0003428 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.5975 ORF TRY4 CAL0003428 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.5977 ORF CEM1 CAL0003432 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.5977 ORF CEM1 CAL0003432 PMID: 12524333|CGD_REF: CAL0080691 homozygous diploid, systematic mutation set (homozygous insertion mutants generated with URA3-ARG4-URA3 (UAU1) cassette) null BWP17 inviable homozygous null mutant strain could not be recovered, suggesting that the gene is essential under the selection conditions C. albicans orf19.5978 ORF CAL0003435 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.5982 ORF RPL18 CAL0003449 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.5984 ORF CAL0003451 PMID: 20141603|CGD_REF: CAL0124951 homozygous diploid, systematic mutation set (homozygous insertion mutants generated with URA3-ARG4-URA3 (UAU1) cassette) null BWP17 colony appearance: abnormal 10% serum or Spider media at 37 deg C colonies are smoother than wild type but mutant is able to form true hyphae under liquid inducing conditions C. albicans orf19.5984 ORF CAL0003451 PMID: 20141603|CGD_REF: CAL0124951 homozygous diploid, systematic mutation set (homozygous insertion mutants generated with URA3-ARG4-URA3 (UAU1) cassette) null BWP17 viable C. albicans orf19.5986 ORF THI4 CAL0003455 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.5987 ORF CAL0003457 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.5989 ORF CAL0003460 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.5989 ORF CAL0003460 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 invasive growth: decreased solid SLAD media C. albicans orf19.5991 ORF CAL0003464 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.5991 ORF CAL0003464 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient SLAD medium C. albicans orf19.5992 ORF WOR2 CAL0003465 PMID: 17880264|CGD_REF: CAL0118619 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.5992 ORF WOR2 CAL0003465 PMID: 20041210|CGD_REF: CAL0124764 homozygous diploid, systematic mutation set null SN152 colony appearance: abnormal YEPD medium at 42 deg C strongly increased colony fuzziness and/or peripheral filamentation C. albicans orf19.5992 ORF WOR2 CAL0003465 PMID: 17880264|CGD_REF: CAL0118619 homozygous diploid, classical genetics null Not recorded phenotypic switching: abnormal defect in maintenance of opaque state C. albicans orf19.5992 ORF WOR2 CAL0003465 PMID: 17880264|CGD_REF: CAL0118619 homozygous diploid, classical genetics null Not recorded phenotypic switching: absent MTLa/MTLa background white-to-opaque switching C. albicans orf19.5992 ORF WOR2 CAL0003465 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.5992 ORF WOR2 CAL0003465 PMID: 22073120|CGD_REF: CAL0000143592 homozygous diploid, classical genetics null BWP17 viable C. albicans orf19.5992 ORF WOR2 CAL0003465 PMID: 22073120|CGD_REF: CAL0000143592 homozygous diploid, classical genetics null BWP17 invasive growth: increased increased agar invasion C. albicans orf19.5992 ORF WOR2 CAL0003465 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: abnormal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.5992 ORF WOR2 CAL0003465 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.5992 ORF WOR2 CAL0003465 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.5994 ORF RHB1 CAL0003468 PMID: 19095072|CGD_REF: CAL0122066 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased Calcofluor White C. albicans orf19.5994 ORF RHB1 CAL0003468 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.5994 ORF RHB1 CAL0003468 PMID: 19095072|CGD_REF: CAL0122066 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.5994 ORF RHB1 CAL0003468 PMID: 19095072|CGD_REF: CAL0122066 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased rapamycin C. albicans orf19.5994 ORF RHB1 CAL0003468 PMID: 19095072|CGD_REF: CAL0122066 heterozygous diploid, classical genetics overexpression SC5314 filamentous growth: absent low nitrogen conditions C. albicans orf19.5994 ORF RHB1 CAL0003468 PMID: 19095072|CGD_REF: CAL0122066 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased Hygromycin B C. albicans orf19.5994 ORF RHB1 CAL0003468 PMID: 19095072|CGD_REF: CAL0122066 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased Congo Red C. albicans orf19.5994 ORF RHB1 CAL0003468 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: increased growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.5994 ORF RHB1 CAL0003468 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.5994 ORF RHB1 CAL0003468 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: decreased rate liquid synthetic complete medium C. albicans orf19.5994 ORF RHB1 CAL0003468 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.5995 ORF MCA1 CAL0003470 PMID: 19049890|CGD_REF: CAL0121262 homozygous diploid, classical genetics null Not recorded vegetative growth: decreased rate both rich and minimal media C. albicans orf19.5995 ORF MCA1 CAL0003470 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.5995 ORF MCA1 CAL0003470 PMID: 19049890|CGD_REF: CAL0121262 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.5995 ORF MCA1 CAL0003470 PMID: 19049890|CGD_REF: CAL0121262 homozygous diploid, classical genetics null Not recorded apoptosis: decreased decreased apoptotic cell death upon H2O2 treatment C. albicans orf19.5995 ORF MCA1 CAL0003470 PMID: 19049890|CGD_REF: CAL0121262 homozygous diploid, classical genetics null Not recorded chemical compound accumulation: decreased reactive oxygen species upon H2O2 treatment C. albicans orf19.5995 ORF MCA1 CAL0003470 PMID: 19049890|CGD_REF: CAL0121262 homozygous diploid, classical genetics null Not recorded chemical compound accumulation: increased trehalose upon H2O2 treatment C. albicans orf19.5995 ORF MCA1 CAL0003470 PMID: 23856128|CGD_REF: CAL0000172540 homozygous diploid, classical genetics null BWP17 resistance to chemicals: decreased propolis C. albicans orf19.5995 ORF MCA1 CAL0003470 PMID: 19596007|CGD_REF: CAL0124094 homozygous diploid, classical genetics null BWP17 protein activity: decreased treatment with 120?mM acetic acid caspase C. albicans orf19.5995 ORF MCA1 CAL0003470 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient YPD medium C. albicans orf19.5995 ORF MCA1 CAL0003470 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient SC medium C. albicans orf19.5995 ORF MCA1 CAL0003470 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient SLAD medium C. albicans orf19.5999 ORF DYN1 CAL0003475 PMID: 15590831|CGD_REF: CAL0082484 homozygous diploid, classical genetics null Not recorded vegetative growth: decreased rate C. albicans orf19.5999 ORF DYN1 CAL0003475 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.5999 ORF DYN1 CAL0003475 PMID: 15590831|CGD_REF: CAL0082484 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.5999 ORF DYN1 CAL0003475 PMID: 15590831|CGD_REF: CAL0082484 heterozygous diploid, classical genetics repressible BWP17 hyphal growth: abnormal defect in nuclear migration into germ tube, hyphae; hyphal growth arrest C. albicans orf19.5999 ORF DYN1 CAL0003475 PMID: 15590831|CGD_REF: CAL0082484 homozygous diploid, classical genetics null BWP17 hyphal growth: abnormal solid Spider or serum-containing media, or liquid serum-containing medium C. albicans orf19.5999 ORF DYN1 CAL0003475 PMID: 15590831|CGD_REF: CAL0082484 homozygous diploid, classical genetics null Not recorded cell shape: abnormal cells are elongated and tend to aggregate C. albicans orf19.5999 ORF DYN1 CAL0003475 PMID: 15590831|CGD_REF: CAL0082484 heterozygous diploid, classical genetics repressible Not recorded nuclear position: abnormal defect in nuclear migration into germ tubes and hyphae C. albicans orf19.5999 ORF DYN1 CAL0003475 PMID: 18211963|CGD_REF: CAL0118861 homozygous diploid, classical genetics null Not recorded pseudohyphal growth: abnormal conditions inducing yeast-form growth pseudohyphal growth occurs along with yeast-form growth C. albicans orf19.600 ORF TRK1 CAL0000875 PMID: 15485849|CGD_REF: CAL0090463 heterozygous diploid, classical genetics null Not recorded small molecule transport: decreased rubidium(1+) decreased influx of rubidium C. albicans orf19.600 ORF TRK1 CAL0000875 PMID: 19175416|CGD_REF: CAL0122293 heterozygous diploid, classical genetics null Not recorded small molecule transport: decreased rubidium(1+) decreased influx of rubidium as an assay for K+ influx C. albicans orf19.600 ORF TRK1 CAL0000875 PMID: 15485849|CGD_REF: CAL0090463 heterozygous diploid, classical genetics null Not recorded toxin resistance: increased human salivary histatin 5 C. albicans orf19.600 ORF TRK1 CAL0000875 PMID: 16377704|CGD_REF: CAL0115300 heterozygous diploid, classical genetics null Not recorded toxin resistance: normal human beta-defensins C. albicans orf19.600 ORF TRK1 CAL0000875 PMID: 16377704|CGD_REF: CAL0115300 heterozygous diploid, classical genetics null Not recorded toxin resistance: increased human salivary histatin 5 and other cationic peptides C. albicans orf19.600 ORF TRK1 CAL0000875 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.600 ORF TRK1 CAL0000875 PMID: 15485849|CGD_REF: CAL0090463 homozygous diploid, classical genetics null Not recorded inviable homozygous null mutant strain could not be recovered, suggesting that the gene is essential under the selection conditions C. albicans orf19.6000 ORF CDR1 CAL0005016 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, competitive growth (haploinsufficient phenotype assay, barcode deletion set) null SC5314 resistance to chemicals: decreased brefeldin A C. albicans orf19.6000 ORF CDR1 CAL0005016 PMID: 19623926|CGD_REF: CAL0124054 heterozygous diploid, competitive growth (haploinsufficient phenotype assay, barcode deletion set) null SC5314 resistance to chemicals: decreased brefeldin A C. albicans orf19.6000 ORF CDR1 CAL0005016 PMID: 15486081|CGD_REF: CAL0082469 heterozygous diploid, classical genetics overexpression Not recorded resistance to chemicals: increased brefeldin A overexpression causes resistance to drugs including azoles, terbinafine, cerulenin, nigericin, and brefeldin A (but not polyene antibiotic drugs) C. albicans orf19.6000 ORF CDR1 CAL0005016 PMID: 8891134|CGD_REF: CAL0080887 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased brefeldin A C. albicans orf19.6000 ORF CDR1 CAL0005016 PMID: 17144665|CGD_REF: CAL0117043 heterozygous diploid, classical genetics reduction of function Not recorded resistance to chemicals: decreased ketoconazole D327N, D327A, D1026N, D1026A, and D327N/D1026N mutations lead to severely impaired ATPase activity and drug efflux C. albicans orf19.6000 ORF CDR1 CAL0005016 PMID: 19223631|CGD_REF: CAL0122395 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased ketoconazole C. albicans orf19.6000 ORF CDR1 CAL0005016 PMID: 8891134|CGD_REF: CAL0080887 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased ketoconazole C. albicans orf19.6000 ORF CDR1 CAL0005016 PMID: 17144665|CGD_REF: CAL0117043 heterozygous diploid, classical genetics reduction of function Not recorded resistance to chemicals: decreased itraconazole D327N, D327A, D1026N, D1026A, and D327N/D1026N mutations lead to severely impaired ATPase activity and drug efflux C. albicans orf19.6000 ORF CDR1 CAL0005016 PMID: 19223631|CGD_REF: CAL0122395 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased itraconazole C. albicans orf19.6000 ORF CDR1 CAL0005016 PMID: 8891134|CGD_REF: CAL0080887 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased itraconazole C. albicans orf19.6000 ORF CDR1 CAL0005016 PMID: 17144665|CGD_REF: CAL0117043 heterozygous diploid, classical genetics reduction of function Not recorded resistance to chemicals: decreased miconazole D327N, D327A, D1026N, D1026A, and D327N/D1026N mutations lead to severely impaired ATPase activity and drug efflux C. albicans orf19.6000 ORF CDR1 CAL0005016 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.6000 ORF CDR1 CAL0005016 PMID: 11694594|CGD_REF: CAL0080865 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.6000 ORF CDR1 CAL0005016 PMID: 11870854|CGD_REF: CAL0080933 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.6000 ORF CDR1 CAL0005016 PMID: 11967831|CGD_REF: CAL0080650 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.6000 ORF CDR1 CAL0005016 PMID: 17604452|CGD_REF: CAL0118249 homozygous diploid, classical genetics null SC5314 viable C. albicans orf19.6000 ORF CDR1 CAL0005016 PMID: 8891134|CGD_REF: CAL0080887 heterozygous diploid, classical genetics null Not recorded viable C. albicans orf19.6000 ORF CDR1 CAL0005016 PMID: 8891134|CGD_REF: CAL0080887 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.6000 ORF CDR1 CAL0005016 PMID: 16475832|CGD_REF: CAL0115547 heterozygous diploid, classical genetics reduction of function Not recorded protein activity: decreased Cdr1p-W326A and Cdr1p-C193A exhibit moderate and severe defects, respectively, in ATPase activity Cdr1p C. albicans orf19.6000 ORF CDR1 CAL0005016 PMID: 15381123|CGD_REF: CAL0082120 heterozygous diploid, classical genetics reduction of function cdr1-K901C (defective in transport and ATPase activities) Not recorded resistance to chemicals: decreased cycloheximide C. albicans orf19.6000 ORF CDR1 CAL0005016 PMID: 15381123|CGD_REF: CAL0082120 heterozygous diploid, classical genetics reduction of function cdr1-K901C (defective in transport and ATPase activities) Not recorded resistance to chemicals: decreased fluconazole C. albicans orf19.6000 ORF CDR1 CAL0005016 PMID: 15381123|CGD_REF: CAL0082120 heterozygous diploid, classical genetics reduction of function cdr1-K901C (defective in transport and ATPase activities) Not recorded resistance to chemicals: decreased miconazole C. albicans orf19.6000 ORF CDR1 CAL0005016 PMID: 15381123|CGD_REF: CAL0082120 heterozygous diploid, classical genetics reduction of function cdr1-K901C (defective in transport and ATPase activities) Not recorded resistance to chemicals: decreased ansiomycin C. albicans orf19.6000 ORF CDR1 CAL0005016 PMID: 11870854|CGD_REF: CAL0080933 homozygous diploid, classical genetics null Not recorded chemical compound accumulation: abnormal phosphatidylethanolamine decreased phosphatidylethanolamine content of plasma membrane C. albicans orf19.6000 ORF CDR1 CAL0005016 PMID: 10029989|CGD_REF: CAL0080910 homozygous diploid, classical genetics null Not recorded chemical compound accumulation: abnormal phosphatidylethanolamine decreased phosphatidylethanolamine content of plasma membrane outer leaflet C. albicans orf19.6000 ORF CDR1 CAL0005016 PMID: 17144665|CGD_REF: CAL0117043 heterozygous diploid, classical genetics reduction of function Not recorded resistance to chemicals: decreased cycloheximide D327N, D327A, D1026N, D1026A, and D327N/D1026N mutations lead to severely impaired ATPase activity and drug efflux C. albicans orf19.6000 ORF CDR1 CAL0005016 PMID: 8891134|CGD_REF: CAL0080887 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased cycloheximide C. albicans orf19.6000 ORF CDR1 CAL0005016 PMID: 15486081|CGD_REF: CAL0082469 heterozygous diploid, classical genetics overexpression Not recorded resistance to chemicals: increased cerulenin overexpression causes resistance to drugs including azoles, terbinafine, cerulenin, nigericin, and brefeldin A (but not polyene antibiotic drugs) C. albicans orf19.6000 ORF CDR1 CAL0005016 PMID: 17144665|CGD_REF: CAL0117043 heterozygous diploid, classical genetics reduction of function Not recorded resistance to chemicals: decreased anisomycin D327N, D327A, D1026N, D1026A, and D327N/D1026N mutations lead to severely impaired ATPase activity and drug efflux C. albicans orf19.6000 ORF CDR1 CAL0005016 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, competitive growth (haploinsufficient phenotype assay, barcode deletion set) null SC5314 resistance to chemicals: decreased radicicol C. albicans orf19.6000 ORF CDR1 CAL0005016 PMID: 19115836|CGD_REF: CAL0122036 heterozygous diploid, competitive growth (haploinsufficient phenotype assay, barcode deletion set) null SC5314 resistance to chemicals: decreased radicicol C. albicans orf19.6000 ORF CDR1 CAL0005016 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, competitive growth (haploinsufficient phenotype assay, barcode deletion set) null SC5314 resistance to chemicals: decreased cytochalasin D C. albicans orf19.6000 ORF CDR1 CAL0005016 PMID: 15486081|CGD_REF: CAL0082469 heterozygous diploid, classical genetics overexpression Not recorded resistance to chemicals: increased nigericin overexpression causes resistance to drugs including azoles, terbinafine, cerulenin, nigericin, and brefeldin A (but not polyene antibiotic drugs) C. albicans orf19.6000 ORF CDR1 CAL0005016 PMID: 8891134|CGD_REF: CAL0080887 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased amorolfine C. albicans orf19.6000 ORF CDR1 CAL0005016 PMID: 8891134|CGD_REF: CAL0080887 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased fluphenazine C. albicans orf19.6000 ORF CDR1 CAL0005016 PMID: 15486081|CGD_REF: CAL0082469 heterozygous diploid, classical genetics overexpression Not recorded resistance to chemicals: increased terbinafine overexpression causes resistance to drugs including azoles, terbinafine, cerulenin, nigericin, and brefeldin A (but not polyene antibiotic drugs) C. albicans orf19.6000 ORF CDR1 CAL0005016 PMID: 8891134|CGD_REF: CAL0080887 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased terbinafine C. albicans orf19.6000 ORF CDR1 CAL0005016 PMID: 15486081|CGD_REF: CAL0082469 heterozygous diploid, classical genetics overexpression Not recorded resistance to chemicals: increased triazoles overexpression causes resistance to drugs including azoles, terbinafine, cerulenin, nigericin, and brefeldin A (but not polyene antibiotic drugs) C. albicans orf19.6000 ORF CDR1 CAL0005016 PMID: 9756759|CGD_REF: CAL0080905 heterozygous diploid, classical genetics overexpression Not recorded resistance to chemicals: increased triazoles C. albicans orf19.6000 ORF CDR1 CAL0005016 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, competitive growth (haploinsufficient phenotype assay, barcode deletion set) null SC5314 resistance to chemicals: decreased fluconazole C. albicans orf19.6000 ORF CDR1 CAL0005016 PMID: 17144665|CGD_REF: CAL0117043 heterozygous diploid, classical genetics reduction of function Not recorded resistance to chemicals: decreased fluconazole D327N, D327A, D1026N, D1026A, and D327N/D1026N mutations lead to severely impaired ATPase activity and drug efflux C. albicans orf19.6000 ORF CDR1 CAL0005016 PMID: 8891134|CGD_REF: CAL0080887 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased fluconazole fluconazole accumulation is also increased C. albicans orf19.6000 ORF CDR1 CAL0005016 PMID: 15328097|CGD_REF: CAL0082113 homozygous diploid, classical genetics null Not recorded resistance to chemicals: increased fluconazole resistance is induced upon adherence to a substrate C. albicans orf19.6000 ORF CDR1 CAL0005016 PMID: 17604452|CGD_REF: CAL0118249 homozygous diploid, classical genetics null SC5314 resistance to chemicals: decreased fluconazole specifically hypersensitive to fluconazole C. albicans orf19.6000 ORF CDR1 CAL0005016 PMID: 11967831|CGD_REF: CAL0080650 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased fluconazole C. albicans orf19.6000 ORF CDR1 CAL0005016 PMID: 11967831|CGD_REF: CAL0080650 heterozygous diploid, classical genetics overexpression Not recorded resistance to chemicals: increased fluconazole C. albicans orf19.6000 ORF CDR1 CAL0005016 PMID: 19223631|CGD_REF: CAL0122395 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased fluconazole C. albicans orf19.6001 ORF SAP3 CAL0005017 PMID: 9284116|CGD_REF: CAL0081802 homozygous diploid, classical genetics null Not recorded vegetative growth: decreased rate YCB/BSA media C. albicans orf19.6001 ORF SAP3 CAL0005017 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.6001 ORF SAP3 CAL0005017 PMID: 15820985|CGD_REF: CAL0082498 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.6001 ORF SAP3 CAL0005017 PMID: 9284116|CGD_REF: CAL0081802 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.6001 ORF SAP3 CAL0005017 PMID: 9485603|CGD_REF: CAL0081808 homozygous diploid, classical genetics null Not recorded adhesion: decreased adhesion to human buccal epithelial cells C. albicans orf19.6001 ORF SAP3 CAL0005017 PMID: 9596782|CGD_REF: CAL0081875 homozygous diploid, classical genetics null Not recorded adhesion: normal adhesion to human umbilical vein endothelial cells C. albicans orf19.6001 ORF SAP3 CAL0005017 PMID: 15845479|CGD_REF: CAL0082755 homozygous diploid, classical genetics null CAI-4 induction of host response: normal wild-type induction of IL-1beta, IL-8, GM-CSF, IFN-gamma, and TNF-alpha ex vivo model of infection (reconstituted human vaginal epithelium) C. albicans orf19.6001 ORF SAP3 CAL0005017 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.6001 ORF SAP3 CAL0005017 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.6001 ORF SAP3 CAL0005017 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.6001 ORF SAP3 CAL0005017 PMID: 12761103|CGD_REF: CAL0081857 homozygous diploid, classical genetics null Not recorded virulence: normal reconstituted human vaginal epithelium wild-type invasion and cell damage ex vivo model of infection C. albicans orf19.6001 ORF SAP3 CAL0005017 PMID: 10540295|CGD_REF: CAL0081826 homozygous diploid, classical genetics null SC5314 virulence: decreased reconstituted human epithelium ex vivo model of infection C. albicans orf19.6001 ORF SAP3 CAL0005017 PMID: 9284116|CGD_REF: CAL0081802 homozygous diploid, classical genetics null Not recorded virulence: decreased guinea pig intravenous infection C. albicans orf19.6001 ORF SAP3 CAL0005017 PMID: 9596782|CGD_REF: CAL0081875 heterozygous diploid, classical genetics null Not recorded virulence: normal human umbilical vein endothelial cells normal damage to human cells in vitro model of infection C. albicans orf19.6001 ORF SAP3 CAL0005017 PMID: 9596782|CGD_REF: CAL0081875 homozygous diploid, classical genetics null Not recorded virulence: normal human umbilical vein endothelial cells normal damage to human cells in vitro model of infection C. albicans orf19.6001 ORF SAP3 CAL0005017 PMID: 9284116|CGD_REF: CAL0081802 homozygous diploid, classical genetics null Not recorded virulence: decreased mouse intravenous infection C. albicans orf19.6001 ORF SAP3 CAL0005017 PMID: 10569785|CGD_REF: CAL0081876 homozygous diploid, classical genetics null CAI-4 virulence: normal mouse peritoneal infection C. albicans orf19.6001 ORF SAP3 CAL0005017 PMID: 9841840|CGD_REF: CAL0081814 homozygous diploid, classical genetics null Not recorded virulence: decreased rat vaginal infection C. albicans orf19.6001 ORF SAP3 CAL0005017 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.6005 ORF HGT5 CAL0005021 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.6007 ORF CAL0005022 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.6008 ORF CAL0005023 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 invasive growth: decreased solid SLAD media C. albicans orf19.6009 ORF SET1 CAL0005024 PMID: 16629671|CGD_REF: CAL0115923 homozygous diploid, classical genetics null Not recorded resistance to enzymatic treatment: normal zymolyase C. albicans orf19.6009 ORF SET1 CAL0005024 PMID: 16629671|CGD_REF: CAL0115923 homozygous diploid, classical genetics null Not recorded resistance to chemicals: normal Calcofluor White C. albicans orf19.6009 ORF SET1 CAL0005024 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.6009 ORF SET1 CAL0005024 PMID: 16629671|CGD_REF: CAL0115923 heterozygous diploid, classical genetics null Not recorded viable C. albicans orf19.6009 ORF SET1 CAL0005024 PMID: 16629671|CGD_REF: CAL0115923 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.6009 ORF SET1 CAL0005024 PMID: 19555456|CGD_REF: CAL0123821 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.6009 ORF SET1 CAL0005024 PMID: 16629671|CGD_REF: CAL0115923 homozygous diploid, classical genetics null Not recorded protein/peptide modification: decreased decreased methylation of residue K4 of histone H3 histone H3 C. albicans orf19.6009 ORF SET1 CAL0005024 PMID: 16629671|CGD_REF: CAL0115923 homozygous diploid, classical genetics null Not recorded resistance to chemicals: normal sodium dodecyl sulfate C. albicans orf19.6009 ORF SET1 CAL0005024 PMID: 16629671|CGD_REF: CAL0115923 homozygous diploid, classical genetics null Not recorded adhesion: decreased adhesion to epithelial cells C. albicans orf19.6009 ORF SET1 CAL0005024 PMID: 16629671|CGD_REF: CAL0115923 homozygous diploid, classical genetics null CAI-4 invasive growth: increased embedded in agar C. albicans orf19.6009 ORF SET1 CAL0005024 PMID: 19555456|CGD_REF: CAL0123821 homozygous diploid, classical genetics null Not recorded phenotypic switching: increased MTLa/MTLa background white-to-opaque switching C. albicans orf19.6009 ORF SET1 CAL0005024 PMID: 16629671|CGD_REF: CAL0115923 homozygous diploid, classical genetics null CAI-4 filamentous growth: normal liquid serum or RPMI; solid serum, Spider, M199, Lee's media C. albicans orf19.6009 ORF SET1 CAL0005024 PMID: 16629671|CGD_REF: CAL0115923 homozygous diploid, classical genetics null Not recorded resistance to chemicals: normal caspofungin C. albicans orf19.6009 ORF SET1 CAL0005024 PMID: 16629671|CGD_REF: CAL0115923 homozygous diploid, classical genetics null Not recorded resistance to chemicals: normal fluconazole C. albicans orf19.6009 ORF SET1 CAL0005024 PMID: 16629671|CGD_REF: CAL0115923 homozygous diploid, classical genetics null Not recorded virulence: decreased exhibits decreased organ colonization mouse intravenous infection C. albicans orf19.6009 ORF SET1 CAL0005024 PMID: 16629671|CGD_REF: CAL0115923 heterozygous diploid, classical genetics null Not recorded virulence: normal mouse intravenous infection C. albicans orf19.6010 ORF CDC5 CAL0005042 PMID: 12802083|CGD_REF: CAL0080866 heterozygous diploid, classical genetics overexpression CAI-4 viable no apparent phenotype C. albicans orf19.6010 ORF CDC5 CAL0005042 PMID: 12802083|CGD_REF: CAL0080866 heterozygous diploid, classical genetics repressible CAI-4 cell cycle progression: abnormal C. albicans orf19.6010 ORF CDC5 CAL0005042 PMID: 12802083|CGD_REF: CAL0080866 heterozygous diploid, classical genetics repressible CAI-4 cell cycle progression in M phase: arrested C. albicans orf19.6010 ORF CDC5 CAL0005042 PMID: 12802083|CGD_REF: CAL0080866 heterozygous diploid, classical genetics repressible CAI-4 filamentous growth: abnormal determinate filamentation (filaments form and die) C. albicans orf19.6011 ORF SIN3 CAL0005043 PMID: 12773383|CGD_REF: CAL0087974 heterozygous diploid, classical genetics (haploinsufficient phenotype assay) null CAI-4 viable heterozygous transposon insertion C. albicans orf19.6011 ORF SIN3 CAL0005043 PMID: 12798685|CGD_REF: CAL0081196 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.6011 ORF SIN3 CAL0005043 PMID: 12773383|CGD_REF: CAL0087974 heterozygous diploid, classical genetics (haploinsufficient phenotype assay) null CAI-4 filamentous growth: decreased solid Spider medium heterozygous transposon insertion C. albicans orf19.6011 ORF SIN3 CAL0005043 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: decreased growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.6011 ORF SIN3 CAL0005043 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: abnormal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.6011 ORF SIN3 CAL0005043 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: decreased rate liquid synthetic complete medium C. albicans orf19.6011 ORF SIN3 CAL0005043 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.6012 ORF CAL0005044 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.6014 ORF RRS1 CAL0005046 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, competitive growth (haploinsufficient phenotype assay, barcode deletion set) null SC5314 resistance to chemicals: decreased 5-fluorouracil C. albicans orf19.6014 ORF RRS1 CAL0005046 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, competitive growth (haploinsufficient phenotype assay, barcode deletion set) null SC5314 resistance to chemicals: decreased tubercidin C. albicans orf19.6014 ORF RRS1 CAL0005046 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, competitive growth (haploinsufficient phenotype assay, barcode deletion set) null SC5314 resistance to chemicals: decreased flucytosine C. albicans orf19.6014 ORF RRS1 CAL0005046 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.6016 ORF CAL0005047 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.6018 ORF LRO1 CAL0005049 PMID: 18179283|CGD_REF: CAL0119040 heterozygous diploid, classical genetics null Not recorded viable UAU1 cassette C. albicans orf19.6018 ORF LRO1 CAL0005049 PMID: 18179283|CGD_REF: CAL0119040 homozygous diploid, classical genetics null Not recorded viable UAU1 cassette C. albicans orf19.6018 ORF LRO1 CAL0005049 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.6018 ORF LRO1 CAL0005049 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.6018 ORF LRO1 CAL0005049 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.6018 ORF LRO1 CAL0005049 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.6020 ORF CAL0005067 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.6022 ORF NRM1 CAL0005069 PMID: 22463761|CGD_REF: CAL0000157109 homozygous diploid, classical genetics null CAI-4 viable C. albicans orf19.6022 ORF NRM1 CAL0005069 PMID: 22463761|CGD_REF: CAL0000157109 homozygous diploid, classical genetics null CAI-4 cell size: decreased C. albicans orf19.6022 ORF NRM1 CAL0005069 PMID: 22463761|CGD_REF: CAL0000157109 homozygous diploid, classical genetics null CAI-4 resistance to chemicals: increased hydroxyurea C. albicans orf19.6023 ORF CAL0005070 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.6023 ORF CAL0005070 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 invasive growth: decreased solid SLAD media C. albicans orf19.6025 ORF CAL0005072 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.6026 ORF ERG2 CAL0005073 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.6026 ORF ERG2 CAL0005073 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, competitive growth (haploinsufficient phenotype assay, barcode deletion set) null SC5314 resistance to chemicals: decreased dyclonine C. albicans orf19.6026 ORF ERG2 CAL0005073 PMID: 15105135|CGD_REF: CAL0080962 unknown ploidy, classical genetics unspecified Other C. albicans resistance to chemicals: decreased terbinafine C. albicans orf19.6026 ORF ERG2 CAL0005073 PMID: 15105135|CGD_REF: CAL0080962 unknown ploidy, classical genetics unspecified Other C. albicans resistance to chemicals: decreased fluconazole|itraconazole|ketoconazole C. albicans orf19.6026 ORF ERG2 CAL0005073 PMID: 15105135|CGD_REF: CAL0080962 unknown ploidy, classical genetics unspecified Other C. albicans resistance to chemicals: decreased 1,10-phenanthroline C. albicans orf19.6026 ORF ERG2 CAL0005073 PMID: 15105135|CGD_REF: CAL0080962 unknown ploidy, classical genetics unspecified Other C. albicans resistance to chemicals: decreased 4-nitroquinoline N-oxide C. albicans orf19.6026 ORF ERG2 CAL0005073 PMID: 15473366|CGD_REF: CAL0082468 unknown ploidy, classical genetics unspecified CAI-8 viable C. albicans orf19.6026 ORF ERG2 CAL0005073 PMID: 1922193|CGD_REF: CAL0081255 unknown ploidy, classical genetics unspecified Other C. albicans resistance to chemicals: increased nystatin C. albicans orf19.6026 ORF ERG2 CAL0005073 PMID: 1922193|CGD_REF: CAL0081255 unknown ploidy, classical genetics unspecified Other C. albicans chemical compound accumulation: abnormal sterol altered plasma membrane sterol content C. albicans orf19.6026 ORF ERG2 CAL0005073 PMID: 1922193|CGD_REF: CAL0081255 unknown ploidy, classical genetics unspecified Other C. albicans viable C. albicans orf19.6026 ORF ERG2 CAL0005073 PMID: 24204207|CGD_REF: CAL0000173572 classical genetics null Other C. albicans resistance to chemicals: increased amphotericin B C. albicans orf19.6026 ORF ERG2 CAL0005073 PMID: 20494978|CGD_REF: CAL0125636 heterozygous diploid, classical genetics null BWP17 resistance to chemicals: decreased clotrimazole (75 uM) growth in liquid culture confirmation of mutant phenotypes for heterozygous transposon insertion strains showing sensitivity in a large-scale assay C. albicans orf19.6026 ORF ERG2 CAL0005073 PMID: 21135205|CGD_REF: CAL0139967 heterozygous diploid, competitive growth (large-scale identification of genes essential for virulence in mouse) repressible CAI-4 virulence: decreased mouse intravenous infection C. albicans orf19.6028 ORF HGC1 CAL0005075 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.6028 ORF HGC1 CAL0005075 PMID: 15071502|CGD_REF: CAL0080862 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.6028 ORF HGC1 CAL0005075 PMID: 15071502|CGD_REF: CAL0080862 homozygous diploid, classical genetics null BWP17 hyphal growth: decreased solid Spider, Lee's, or M199 ph 7.0 media C. albicans orf19.6028 ORF HGC1 CAL0005075 PMID: 21407800|CGD_REF: CAL0141800 homozygous diploid, classical genetics null BWP17 interaction with host/environment: abnormal significantly reduces adhesion, invasion, and damage to epithelial cells ex vivo model of infection C. albicans orf19.6028 ORF HGC1 CAL0005075 PMID: 23637598|CGD_REF: CAL0000172002 homozygous diploid, classical genetics null SC5314 biofilm formation: decreased 37 degrees C in Spider medium C. albicans orf19.6028 ORF HGC1 CAL0005075 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 invasive growth: decreased solid SLAD media C. albicans orf19.603 ORF IMP4 CAL0000877 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.6031 ORF VPS27 CAL0005098 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.6031 ORF VPS27 CAL0005098 PMID: 20581294|CGD_REF: CAL0125802 homozygous diploid, classical genetics null BWP17 viable a log less CFU/g tongue compared to mice infected with wild type mouse oropharyngeal infection (cortisone-immunosuppressed mice) C. albicans orf19.6032 ORF SPE1 CAL0005099 PMID: 14663094|CGD_REF: CAL0080633 homozygous diploid, systematic mutation set (homozygous insertion mutants generated with URA3-ARG4-URA3 (UAU1) cassette) null BWP17 viable C. albicans orf19.6032 ORF SPE1 CAL0005099 PMID: 23672250|CGD_REF: CAL0000172360 homozygous diploid, classical genetics null SC5314 resistance to chemicals: decreased amphotericin B C. albicans orf19.6033 ORF CMP1 CAL0005100 PMID: 12753189|CGD_REF: CAL0080803 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased brefeldin A C. albicans orf19.6033 ORF CMP1 CAL0005100 PMID: 12753189|CGD_REF: CAL0080803 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased lithium(1+) C. albicans orf19.6033 ORF CMP1 CAL0005100 PMID: 16790813|CGD_REF: CAL0116203 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased lithium(1+) C. albicans orf19.6033 ORF CMP1 CAL0005100 PMID: 12753189|CGD_REF: CAL0080803 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased Calcofluor White C. albicans orf19.6033 ORF CMP1 CAL0005100 PMID: 12753189|CGD_REF: CAL0080803 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased itraconazole wild-type MIC, but decreased survival at drug concentrations over MIC C. albicans orf19.6033 ORF CMP1 CAL0005100 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.6033 ORF CMP1 CAL0005100 PMID: 12753189|CGD_REF: CAL0080803 heterozygous diploid, classical genetics null Not recorded viable C. albicans orf19.6033 ORF CMP1 CAL0005100 PMID: 12753189|CGD_REF: CAL0080803 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.6033 ORF CMP1 CAL0005100 PMID: 12933882|CGD_REF: CAL0081042 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.6033 ORF CMP1 CAL0005100 PMID: 18708562|CGD_REF: CAL0119375 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.6033 ORF CMP1 CAL0005100 PMID: 16790813|CGD_REF: CAL0116203 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased sodium dodecyl sulfate C. albicans orf19.6033 ORF CMP1 CAL0005100 PMID: 12933882|CGD_REF: CAL0081042 homozygous diploid, classical genetics null Not recorded alkaline pH resistance: decreased C. albicans orf19.6033 ORF CMP1 CAL0005100 PMID: 16790813|CGD_REF: CAL0116203 homozygous diploid, classical genetics null Not recorded alkaline pH resistance: decreased C. albicans orf19.6033 ORF CMP1 CAL0005100 PMID: 12753189|CGD_REF: CAL0080803 homozygous diploid, classical genetics null CAF2-1 hyphal growth: absent serum-containing medium C. albicans orf19.6033 ORF CMP1 CAL0005100 PMID: 12753189|CGD_REF: CAL0080803 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased voriconazole wild-type MIC, but decreased survival at drug concentrations over MIC C. albicans orf19.6033 ORF CMP1 CAL0005100 PMID: 12753189|CGD_REF: CAL0080803 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased mycophenolic acid C. albicans orf19.6033 ORF CMP1 CAL0005100 PMID: 12933882|CGD_REF: CAL0081042 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased sodium chloride C. albicans orf19.6033 ORF CMP1 CAL0005100 PMID: 12753189|CGD_REF: CAL0080803 homozygous diploid, classical genetics null CAF2-1 colony appearance: abnormal solid YEPD medium wrinkled colonies C. albicans orf19.6033 ORF CMP1 CAL0005100 PMID: 12753189|CGD_REF: CAL0080803 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased caffeine C. albicans orf19.6033 ORF CMP1 CAL0005100 PMID: 16790813|CGD_REF: CAL0116203 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased manganese(2+) C. albicans orf19.6033 ORF CMP1 CAL0005100 PMID: 12753189|CGD_REF: CAL0080803 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased sodium(1+) C. albicans orf19.6033 ORF CMP1 CAL0005100 PMID: 16790813|CGD_REF: CAL0116203 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased sodium(1+) C. albicans orf19.6033 ORF CMP1 CAL0005100 PMID: 12753189|CGD_REF: CAL0080803 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased calcium(2+) C. albicans orf19.6033 ORF CMP1 CAL0005100 PMID: 16790813|CGD_REF: CAL0116203 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased calcium(2+) C. albicans orf19.6033 ORF CMP1 CAL0005100 PMID: 12753189|CGD_REF: CAL0080803 homozygous diploid, classical genetics null CAF2-1 filamentous growth: decreased solid SLAD medium C. albicans orf19.6033 ORF CMP1 CAL0005100 PMID: 12753189|CGD_REF: CAL0080803 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased amorolfine decreased MIC, and decreased survival at drug concentrations over MIC C. albicans orf19.6033 ORF CMP1 CAL0005100 PMID: 19649312|CGD_REF: CAL0123929 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased micafungin (30 ng/ml) micafungin treatment is fungicidal C. albicans orf19.6033 ORF CMP1 CAL0005100 PMID: 12753189|CGD_REF: CAL0080803 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased caspofungin wild-type MIC, but decreased survival at drug concentrations over MIC C. albicans orf19.6033 ORF CMP1 CAL0005100 PMID: 12753189|CGD_REF: CAL0080803 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased fluphenazine C. albicans orf19.6033 ORF CMP1 CAL0005100 PMID: 12753189|CGD_REF: CAL0080803 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased pradimycin C. albicans orf19.6033 ORF CMP1 CAL0005100 PMID: 12753189|CGD_REF: CAL0080803 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased terbinafine decreased MIC, and decreased survival at drug concentrations over MIC C. albicans orf19.6033 ORF CMP1 CAL0005100 PMID: 19115836|CGD_REF: CAL0122036 heterozygous diploid, competitive growth (haploinsufficient phenotype assay, barcode deletion set) null SC5314 resistance to chemicals: decreased virgineone C. albicans orf19.6033 ORF CMP1 CAL0005100 PMID: 12753189|CGD_REF: CAL0080803 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased Congo Red C. albicans orf19.6033 ORF CMP1 CAL0005100 PMID: 12753189|CGD_REF: CAL0080803 heterozygous diploid, classical genetics activation CAF2-1 resistance to chemicals: increased fluconazole increased survival at drug concentrations over MIC; CNAtr allele, truncated at residue 499 C. albicans orf19.6033 ORF CMP1 CAL0005100 PMID: 12753189|CGD_REF: CAL0080803 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased fluconazole wild-type MIC, but decreased survival at drug concentrations over MIC C. albicans orf19.6033 ORF CMP1 CAL0005100 PMID: 16790813|CGD_REF: CAL0116203 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased fluconazole C. albicans orf19.6033 ORF CMP1 CAL0005100 PMID: 23028789|CGD_REF: CAL0000157931 homozygous diploid, classical genetics null CAI-4 apoptosis: decreased C. albicans orf19.6033 ORF CMP1 CAL0005100 PMID: 18708562|CGD_REF: CAL0119375 homozygous diploid, classical genetics null Not recorded virulence: decreased insect infection C. albicans orf19.6033 ORF CMP1 CAL0005100 PMID: 12753189|CGD_REF: CAL0080803 heterozygous diploid, classical genetics null Not recorded virulence: decreased decreased kidney colonization; phenotype is intermediate between that of wild type and the homozygous null mutant mouse intravenous infection C. albicans orf19.6033 ORF CMP1 CAL0005100 PMID: 12753189|CGD_REF: CAL0080803 homozygous diploid, classical genetics null Not recorded virulence: decreased exhibits decreased kidney colonization mouse intravenous infection C. albicans orf19.6033 ORF CMP1 CAL0005100 PMID: 16790813|CGD_REF: CAL0116203 homozygous diploid, classical genetics null Not recorded virulence: decreased various mouse models C. albicans orf19.6033 ORF CMP1 CAL0005100 PMID: 20865172|CGD_REF: CAL0126252 homozygous diploid, classical genetics null SN95 resistance to chemicals: decreased fluconazole C. albicans orf19.6033 ORF CMP1 CAL0005100 PMID: 20865172|CGD_REF: CAL0126252 homozygous diploid, classical genetics null SN95 resistance to chemicals: decreased fenpropimorph C. albicans orf19.6033 ORF CMP1 CAL0005100 PMID: 20865172|CGD_REF: CAL0126252 homozygous diploid, classical genetics null SN95 resistance to chemicals: decreased terbinafine C. albicans orf19.6034 ORF TUB2 CAL0005101 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, competitive growth (haploinsufficient phenotype assay, barcode deletion set) null SC5314 vegetative growth: decreased rate C. albicans orf19.6034 ORF TUB2 CAL0005101 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.6034 ORF TUB2 CAL0005101 PMID: 16215177|CGD_REF: CAL0114838 heterozygous diploid, classical genetics unspecified Not recorded hyphal growth: decreased rate C. albicans orf19.6034 ORF TUB2 CAL0005101 PMID: 16215177|CGD_REF: CAL0114838 heterozygous diploid, classical genetics unspecified Not recorded cell cycle passage through the metaphase-anaphase transition: delayed during hyphal growth C. albicans orf19.6034 ORF TUB2 CAL0005101 PMID: 16215177|CGD_REF: CAL0114838 heterozygous diploid, classical genetics unspecified Not recorded cell cycle progression through the G1/S phase transition: delayed during hyphal growth C. albicans orf19.6034 ORF TUB2 CAL0005101 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, competitive growth (haploinsufficient phenotype assay, barcode deletion set) null SC5314 resistance to chemicals: normal benomyl C. albicans orf19.6034 ORF TUB2 CAL0005101 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, competitive growth (haploinsufficient phenotype assay, barcode deletion set) null SC5314 resistance to chemicals: decreased nocodazole C. albicans orf19.6035 ORF CAL0005102 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: decreased growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.6035 ORF CAL0005102 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.6035 ORF CAL0005102 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.6036 ORF RIC1 CAL0005103 PMID: 14663094|CGD_REF: CAL0080633 homozygous diploid, systematic mutation set (homozygous insertion mutants generated with URA3-ARG4-URA3 (UAU1) cassette) null BWP17 viable C. albicans orf19.6037 ORF ASM3 CAL0005104 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.6037 ORF ASM3 CAL0005104 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.6037 ORF ASM3 CAL0005104 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.6037 ORF ASM3 CAL0005104 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.6037 ORF ASM3 CAL0005104 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 invasive growth: decreased solid SLAD media C. albicans orf19.6037 ORF ASM3 CAL0005104 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.6038 ORF UGA32 CAL0005105 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.6038 ORF UGA32 CAL0005105 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.6038 ORF UGA32 CAL0005105 PMID: 22073120|CGD_REF: CAL0000143592 homozygous diploid, classical genetics null BWP17 viable C. albicans orf19.6038 ORF UGA32 CAL0005105 PMID: 22073120|CGD_REF: CAL0000143592 homozygous diploid, classical genetics null BWP17 hyphal growth: increased C. albicans orf19.6038 ORF UGA32 CAL0005105 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.6038 ORF UGA32 CAL0005105 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.6039 ORF CAL0005107 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.604 ORF CAL0000878 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.6040 ORF SNF7 CAL0005125 PMID: 15590834|CGD_REF: CAL0082485 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased lithium(1+) C. albicans orf19.6040 ORF SNF7 CAL0005125 PMID: 15590834|CGD_REF: CAL0082485 homozygous diploid, classical genetics null BWP17 germ tube formation: decreased liquid serum-containing medium C. albicans orf19.6040 ORF SNF7 CAL0005125 PMID: 17005841|CGD_REF: CAL0116696 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased Calcofluor White C. albicans orf19.6040 ORF SNF7 CAL0005125 PMID: 17005841|CGD_REF: CAL0116696 homozygous diploid, classical genetics null Not recorded resistance to chemicals: normal flucytosine C. albicans orf19.6040 ORF SNF7 CAL0005125 PMID: 15590834|CGD_REF: CAL0082485 homozygous diploid, classical genetics null Not recorded vacuolar transport: decreased defect in multivesicular body (MVB) transport to the vacuole C. albicans orf19.6040 ORF SNF7 CAL0005125 PMID: 18974864|CGD_REF: CAL0120463 homozygous diploid, classical genetics null Not recorded vacuolar transport: decreased defect in multivesicular body (MVB) transport to the vacuole C. albicans orf19.6040 ORF SNF7 CAL0005125 PMID: 15590834|CGD_REF: CAL0082485 homozygous diploid, classical genetics null Not recorded vegetative growth: decreased rate rich medium effect is slight C. albicans orf19.6040 ORF SNF7 CAL0005125 PMID: 17005841|CGD_REF: CAL0116696 homozygous diploid, classical genetics null Not recorded vegetative growth: decreased rate C. albicans orf19.6040 ORF SNF7 CAL0005125 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.6040 ORF SNF7 CAL0005125 PMID: 15371534|CGD_REF: CAL0082134 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.6040 ORF SNF7 CAL0005125 PMID: 15590834|CGD_REF: CAL0082485 heterozygous diploid, classical genetics null Not recorded viable C. albicans orf19.6040 ORF SNF7 CAL0005125 PMID: 15590834|CGD_REF: CAL0082485 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.6040 ORF SNF7 CAL0005125 PMID: 15590834|CGD_REF: CAL0082485 homozygous diploid, classical genetics null Not recorded protein/peptide modification: absent Rim101p is not processed Rim101p C. albicans orf19.6040 ORF SNF7 CAL0005125 PMID: 17005841|CGD_REF: CAL0116696 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased sodium dodecyl sulfate C. albicans orf19.6040 ORF SNF7 CAL0005125 PMID: 15590834|CGD_REF: CAL0082485 homozygous diploid, classical genetics null Not recorded alkaline pH resistance: decreased pH 9 C. albicans orf19.6040 ORF SNF7 CAL0005125 PMID: 16299290|CGD_REF: CAL0115041 homozygous diploid, classical genetics null Not recorded alkaline pH resistance: decreased C. albicans orf19.6040 ORF SNF7 CAL0005125 PMID: 15371534|CGD_REF: CAL0082134 homozygous diploid, classical genetics null BWP17 hyphal growth: absent solid medium, alkaline pH C. albicans orf19.6040 ORF SNF7 CAL0005125 PMID: 17005841|CGD_REF: CAL0116696 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased voriconazole C. albicans orf19.6040 ORF SNF7 CAL0005125 PMID: 17005841|CGD_REF: CAL0116696 homozygous diploid, classical genetics null Not recorded resistance to chemicals: normal amphotericin B C. albicans orf19.6040 ORF SNF7 CAL0005125 PMID: 16299290|CGD_REF: CAL0115041 homozygous diploid, classical genetics null Not recorded endocytosis: abnormal abnormal uptake of FM4-64 C. albicans orf19.6040 ORF SNF7 CAL0005125 PMID: 18974864|CGD_REF: CAL0120463 homozygous diploid, classical genetics null Not recorded endocytosis: decreased defect in uptake of low concentrations of histatin-5 antimicrobial salivary peptide into the vacuole C. albicans orf19.6040 ORF SNF7 CAL0005125 PMID: 15590834|CGD_REF: CAL0082485 homozygous diploid, classical genetics null BWP17 filamentous growth: absent solid M199 medium, pH 8 C. albicans orf19.6040 ORF SNF7 CAL0005125 PMID: 17005841|CGD_REF: CAL0116696 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased micafungin C. albicans orf19.6040 ORF SNF7 CAL0005125 PMID: 17005841|CGD_REF: CAL0116696 homozygous diploid, classical genetics null Not recorded resistance to chemicals: normal nikkomycin Z C. albicans orf19.6040 ORF SNF7 CAL0005125 PMID: 17005841|CGD_REF: CAL0116696 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased caspofungin C. albicans orf19.6040 ORF SNF7 CAL0005125 PMID: 18466294|CGD_REF: CAL0119004 homozygous diploid, classical genetics null Not recorded utilization of iron source: absent hemoglobin C. albicans orf19.6040 ORF SNF7 CAL0005125 PMID: 17005841|CGD_REF: CAL0116696 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased fluconazole C. albicans orf19.6040 ORF SNF7 CAL0005125 PMID: 22427429|CGD_REF: CAL0000156990 homozygous diploid, classical genetics null BWP17 protein/peptide modification: absent mutants don't process RIM8-HA RIM8-HA C. albicans orf19.6040 ORF SNF7 CAL0005125 PMID: 22427429|CGD_REF: CAL0000156990 homozygous diploid, classical genetics null BWP17 protein/peptide modification: absent Rim8-HA was not modified to the 95-105 kD forms in this mutant at pH 8 Rim8-HA C. albicans orf19.6040 ORF SNF7 CAL0005125 PMID: 22427429|CGD_REF: CAL0000156990 homozygous diploid, classical genetics null BWP17 protein/peptide modification: abnormal defective for RIM8-HA-processing RIM8-HA C. albicans orf19.6040 ORF SNF7 CAL0005125 PMID: 16299290|CGD_REF: CAL0115041 homozygous diploid, classical genetics null Not recorded virulence: decreased mouse intravenous infection C. albicans orf19.6040 ORF SNF7 CAL0005125 PMID: 20026677|CGD_REF: CAL0124872 homozygous diploid, classical genetics null snf7::ARG4/snf7::URA3-dpl200 BWP17 metal resistance: decreased lithium(1+) C. albicans orf19.6040 ORF SNF7 CAL0005125 PMID: 20026677|CGD_REF: CAL0124872 homozygous diploid, classical genetics null snf7::ARG4/snf7::URA3-dpl200 BWP17 alkaline pH resistance: decreased C. albicans orf19.6040 ORF SNF7 CAL0005125 PMID: 20026677|CGD_REF: CAL0124872 homozygous diploid, classical genetics null snf7::ARG4/snf7::URA3-dpl200 BWP17 endocytosis: decreased abolished delivery of FM 4-64 to the vacuole C. albicans orf19.6040 ORF SNF7 CAL0005125 PMID: 20026677|CGD_REF: CAL0124872 homozygous diploid, classical genetics null snf7::ARG4/snf7::URA3-dpl200 BWP17 germ tube formation: decreased C. albicans orf19.6040 ORF SNF7 CAL0005125 PMID: 20581294|CGD_REF: CAL0125802 homozygous diploid, classical genetics null BWP17 alkaline pH resistance: decreased YPD pH 9, 2 days at 37 degrees C C. albicans orf19.6040 ORF SNF7 CAL0005125 PMID: 20581294|CGD_REF: CAL0125802 homozygous diploid, classical genetics null BWP17 viable C. albicans orf19.6040 ORF SNF7 CAL0005125 PMID: 20581294|CGD_REF: CAL0125802 homozygous diploid, classical genetics null BWP17 virulence: decreased nearly two logs less CFU/g tongue than wild type mouse oropharyngeal infection (cortisone-immunosuppressed mice) C. albicans orf19.6040 ORF SNF7 CAL0005125 PMID: 20581294|CGD_REF: CAL0125802 homozygous diploid, classical genetics null BWP17 protein/peptide modification: absent Rim101p C. albicans orf19.6040 ORF SNF7 CAL0005125 PMID: 20581294|CGD_REF: CAL0125802 homozygous diploid, classical genetics null BWP17 hyphal growth: absent M199 pH 8 plates, 37 degrees C, 6 days no peripheral hyphae produced C. albicans orf19.6040 ORF SNF7 CAL0005125 PMID: 20581294|CGD_REF: CAL0125802 homozygous diploid, classical genetics null BWP17 metal resistance: decreased lithium chloride (150 mM) YPD plus 150 mM lithium chloride C. albicans orf19.6040 ORF SNF7 CAL0005125 PMID: 20581294|CGD_REF: CAL0125802 homozygous diploid, classical genetics null BWP17 resistance to chemicals: decreased iron chelators YPD plus 150 micromolar bathophenanthrolinedisulfonic acid (BPS) C. albicans orf19.6041 ORF RPO41 CAL0005126 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.6041 ORF RPO41 CAL0005126 PMID: 21135205|CGD_REF: CAL0139967 heterozygous diploid, large-scale survey (large-scale identification of genes essential for virulence in mouse) repressible CAI-4 virulence: absent mouse intravenous infection C. albicans orf19.6043 ORF CAL0005127 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.6044 ORF MOB2 CAL0005128 PMID: 18843050|CGD_REF: CAL0120345 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased Calcofluor White C. albicans orf19.6044 ORF MOB2 CAL0005128 PMID: 18843050|CGD_REF: CAL0120345 heterozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased itraconazole sensitivity is intermediate between that of the homozygous null mutant and wild type C. albicans orf19.6044 ORF MOB2 CAL0005128 PMID: 18843050|CGD_REF: CAL0120345 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased itraconazole C. albicans orf19.6044 ORF MOB2 CAL0005128 PMID: 18843050|CGD_REF: CAL0120345 homozygous diploid, classical genetics null Not recorded vegetative growth: decreased rate C. albicans orf19.6044 ORF MOB2 CAL0005128 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.6044 ORF MOB2 CAL0005128 PMID: 18843050|CGD_REF: CAL0120345 heterozygous diploid, classical genetics null Not recorded viable URA3-blaster technique C. albicans orf19.6044 ORF MOB2 CAL0005128 PMID: 18843050|CGD_REF: CAL0120345 homozygous diploid, classical genetics null Not recorded viable URA3-blaster technique C. albicans orf19.6044 ORF MOB2 CAL0005128 PMID: 19779551|CGD_REF: CAL0124331 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.6044 ORF MOB2 CAL0005128 PMID: 18843050|CGD_REF: CAL0120345 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased sodium dodecyl sulfate C. albicans orf19.6044 ORF MOB2 CAL0005128 PMID: 18843050|CGD_REF: CAL0120345 homozygous diploid, classical genetics null Not recorded actin cytoskeleton morphology: abnormal defect in polarization of cortical actin patches, in both yeast-form and hyphal cells C. albicans orf19.6044 ORF MOB2 CAL0005128 PMID: 18843050|CGD_REF: CAL0120345 homozygous diploid, classical genetics null CAI-4 hyphal growth: decreased solid and liquid media C. albicans orf19.6044 ORF MOB2 CAL0005128 PMID: 19779551|CGD_REF: CAL0124331 homozygous diploid, classical genetics null CAF2-1 hyphal growth: abnormal serum-containing medium at 37 deg C C. albicans orf19.6044 ORF MOB2 CAL0005128 PMID: 18843050|CGD_REF: CAL0120345 homozygous diploid, classical genetics null Not recorded cell cycle progression: abnormal cells are multinucleate C. albicans orf19.6044 ORF MOB2 CAL0005128 PMID: 18843050|CGD_REF: CAL0120345 homozygous diploid, classical genetics null Not recorded cell shape: abnormal cells are round and enlarged C. albicans orf19.6044 ORF MOB2 CAL0005128 PMID: 18843050|CGD_REF: CAL0120345 homozygous diploid, classical genetics null Not recorded hypoosmotic stress resistance: decreased cells lyse in liquid YPD C. albicans orf19.6044 ORF MOB2 CAL0005128 PMID: 18843050|CGD_REF: CAL0120345 homozygous diploid, classical genetics null Not recorded cell size: increased cells are round, large, and heterogeneous in size C. albicans orf19.6044 ORF MOB2 CAL0005128 PMID: 19779551|CGD_REF: CAL0124331 homozygous diploid, classical genetics null Not recorded colony appearance: abnormal solid Spider medium C. albicans orf19.6044 ORF MOB2 CAL0005128 PMID: 18843050|CGD_REF: CAL0120345 homozygous diploid, classical genetics null Not recorded cytokinesis: absent C. albicans orf19.6044 ORF MOB2 CAL0005128 PMID: 18843050|CGD_REF: CAL0120345 homozygous diploid, classical genetics null Not recorded plasma membrane morphology: abnormal lack of polarized lipid domains (lipid rafts) C. albicans orf19.6044 ORF MOB2 CAL0005128 PMID: 18843050|CGD_REF: CAL0120345 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased Hygromycin B C. albicans orf19.6044 ORF MOB2 CAL0005128 PMID: 18843050|CGD_REF: CAL0120345 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased Congo Red C. albicans orf19.6044 ORF MOB2 CAL0005128 PMID: 18843050|CGD_REF: CAL0120345 heterozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased fluconazole sensitivity is intermediate between that of the homozygous null mutant and wild type C. albicans orf19.6044 ORF MOB2 CAL0005128 PMID: 18843050|CGD_REF: CAL0120345 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased fluconazole C. albicans orf19.6044 ORF MOB2 CAL0005128 PMID: 21593210|CGD_REF: CAL0142017 homozygous diploid, classical genetics null Other C. albicans protein/peptide distribution: abnormal Cbk1p doesn't localize to regions of polarized growth in the mob2 mutant Cbk1p-YFP C. albicans orf19.6044 ORF MOB2 CAL0005128 PMID: 21593210|CGD_REF: CAL0142017 heterozygous diploid, classical genetics reduction of function mob2-S44A/S51A/S67A/S97A (4 consensus Cbk1p phosphorylation sites mutated to alanines) Other C. albicans protein/peptide distribution: abnormal Cbk1p doesn't localize to regions of polarized growth in the mob2 mutant Cbk1p-YFP C. albicans orf19.6044 ORF MOB2 CAL0005128 PMID: 21593210|CGD_REF: CAL0142017 heterozygous diploid, classical genetics activation mob2-S44E/S51E/S67E/S97E (4 consensus Cbk1p phosphorylation site serines mutated to glutamic acid) Other C. albicans protein/peptide distribution: abnormal Kel1p-GFP was disorganized in the filaments during hyphal-growth inducing conditions Kel1p-GFP C. albicans orf19.6044 ORF MOB2 CAL0005128 PMID: 21593210|CGD_REF: CAL0142017 heterozygous diploid, classical genetics reduction of function mob2-S44A/S51A/S67A/S97A|4 (4 consensus Cbk1p phosphorylation sites mutated to alanines to prevent phosphorylation) Other C. albicans hyphal growth: abnormal shorter hyphae with enlarged tips that display activation of cell separation C. albicans orf19.6044 ORF MOB2 CAL0005128 PMID: 21593210|CGD_REF: CAL0142017 heterozygous diploid, classical genetics reduction of function mob2-S44A/S51A/S67A/S97A|4 (4 consensus Cbk1p phosphorylation sites mutated to alanines to prevent phosphorylation) Other C. albicans protein/peptide distribution: abnormal Spa2p-GFP C. albicans orf19.6044 ORF MOB2 CAL0005128 PMID: 22589718|CGD_REF: CAL0000157315 homozygous diploid, classical genetics null BWP17 biofilm formation: decreased C. albicans orf19.6045 ORF CAL0005129 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.6045 ORF CAL0005129 PMID: 20132453|CGD_REF: CAL0125003 homozygous diploid, classical genetics null psd1/psd1::SAT1-FLP SC5314 filamentous growth YPD plus 10% serum phenotype additive in combination with psd2 null C. albicans orf19.6045 ORF CAL0005129 PMID: 20132453|CGD_REF: CAL0125003 homozygous diploid, classical genetics null psd1/psd1::SAT1-FLP SC5314 viable C. albicans orf19.6045 ORF CAL0005129 PMID: 20132453|CGD_REF: CAL0125003 homozygous diploid, classical genetics null psd1/psd1::SAT1-FLP SC5314 filamentous growth Spider plus 1 mM ethanolamine phenotype additive in combination with psd2 null C. albicans orf19.6046 ORF APC1 CAL0005130 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.6046 ORF APC1 CAL0005130 PMID: 14507372|CGD_REF: CAL0088818 heterozygous diploid, large-scale survey (large-scale identification of essential genes by gene replacement and conditional expression (GRACE) method) repressible CAI-4 inviable one allele is deleted and the other is placed under repressible Tet promoter C. albicans orf19.6046 ORF APC1 CAL0005130 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient YPD medium C. albicans orf19.6052 ORF CNS1 CAL0005143 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.6052 ORF CNS1 CAL0005143 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, competitive growth (haploinsufficient phenotype assay, barcode deletion set) null SC5314 resistance to chemicals: decreased radicicol C. albicans orf19.6053 ORF CIS2 CAL0005144 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.6053 ORF CIS2 CAL0005144 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.6053 ORF CIS2 CAL0005144 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.6053 ORF CIS2 CAL0005144 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.6053 ORF CIS2 CAL0005144 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.6057 ORF CAL0005148 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.6057 ORF CAL0005148 PMID: 21135205|CGD_REF: CAL0139967 heterozygous diploid, large-scale survey (large-scale identification of genes essential for virulence in mouse) repressible CAI-4 virulence: absent mouse intravenous infection C. albicans orf19.6058 ORF GLO1 CAL0005149 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.6059 ORF TTR1 CAL0005151 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.6059 ORF TTR1 CAL0005151 PMID: 18273798|CGD_REF: CAL0118826 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.6059 ORF TTR1 CAL0005151 PMID: 18273798|CGD_REF: CAL0118826 homozygous diploid, classical genetics null Not recorded protein activity: normal phospholipase C. albicans orf19.6059 ORF TTR1 CAL0005151 PMID: 18273798|CGD_REF: CAL0118826 homozygous diploid, classical genetics null Not recorded protein activity: normal YCB/BSA media secreted protease C. albicans orf19.6059 ORF TTR1 CAL0005151 PMID: 18273798|CGD_REF: CAL0118826 homozygous diploid, classical genetics null Not recorded adhesion: normal adhesion to human buccal epithelial cells C. albicans orf19.6059 ORF TTR1 CAL0005151 PMID: 18273798|CGD_REF: CAL0118826 homozygous diploid, classical genetics null Not recorded oxidative stress resistance: normal hydrogen peroxide C. albicans orf19.6059 ORF TTR1 CAL0005151 PMID: 18273798|CGD_REF: CAL0118826 homozygous diploid, classical genetics null Not recorded colony appearance: normal Spider or GlcNAc agar C. albicans orf19.6059 ORF TTR1 CAL0005151 PMID: 18273798|CGD_REF: CAL0118826 homozygous diploid, classical genetics null Not recorded oxidative stress resistance: increased diamide (2.5 mM) C. albicans orf19.6059 ORF TTR1 CAL0005151 PMID: 18273798|CGD_REF: CAL0118826 homozygous diploid, classical genetics null Not recorded oxidative stress resistance: decreased menadione C. albicans orf19.6059 ORF TTR1 CAL0005151 PMID: 18273798|CGD_REF: CAL0118826 homozygous diploid, classical genetics null CAI-4 resistance to killing by host cells: decreased in vitro model of infection (human polymorphonuclear neutrophils) C. albicans orf19.6059 ORF TTR1 CAL0005151 PMID: 23285201|CGD_REF: CAL0000158306 homozygous diploid, classical genetics null BWP17 resistance to killing by host cells: decreased human neutrophils C. albicans orf19.6059 ORF TTR1 CAL0005151 PMID: 18273798|CGD_REF: CAL0118826 homozygous diploid, classical genetics null Not recorded virulence: decreased mouse intravenous infection C. albicans orf19.6059 ORF TTR1 CAL0005151 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient YPD medium C. albicans orf19.6060 ORF GCN20 CAL0005158 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.6061 ORF CAL0005160 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.6063 ORF UBP6 CAL0005163 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.6066 ORF CAL0005169 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.6068 ORF SVF1 CAL0005170 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.607 ORF CAL0000882 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.6070 ORF ENA2 CAL0005183 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.6072 ORF CDC13 CAL0005185 PMID: 20008938|CGD_REF: CAL0124723 homozygous diploid, classical genetics null BWP17 inviable failure to obtain homozygous null mutants indicates the gene is essential C. albicans orf19.6073 ORF HMX1 CAL0005187 PMID: 12634327|CGD_REF: CAL0081388 homozygous diploid, classical genetics null Not recorded utilization of iron source: decreased hemin C. albicans orf19.6073 ORF HMX1 CAL0005187 PMID: 14615478|CGD_REF: CAL0081389 homozygous diploid, classical genetics null Not recorded utilization of iron source: decreased poor growth under iron-limiting conditions C. albicans orf19.6073 ORF HMX1 CAL0005187 PMID: 14615478|CGD_REF: CAL0081389 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.6073 ORF HMX1 CAL0005187 PMID: 21414038|CGD_REF: CAL0141808 homozygous diploid, classical genetics null BWP17 viable C. albicans orf19.6073 ORF HMX1 CAL0005187 PMID: 20800092|CGD_REF: CAL0126189 homozygous diploid, classical genetics null SC5314 virulence: decreased Exogenous carbon monoxide supplied to the mice partially restores virulence C. albicans orf19.6074 ORF HBR1 CAL0005189 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.6074 ORF HBR1 CAL0005189 PMID: 15189997|CGD_REF: CAL0081423 homozygous diploid, classical genetics null Not recorded inviable C. albicans orf19.6074 ORF HBR1 CAL0005189 PMID: 15189997|CGD_REF: CAL0081423 heterozygous diploid, classical genetics null Not recorded phenotypic switching: increased opaque-to-white switching C. albicans orf19.6074 ORF HBR1 CAL0005189 PMID: 21372131|CGD_REF: CAL0141751 heterozygous diploid, classical genetics repressible HBR1/MET3(p)-HBR1(G19S) (P-loop mutation, phenotype also observed for allele (K22Q)) BWP17 RNA accumulation: increased +Met and -Met (repressing and non-repressing conditions) one mutant allele is sufficient to decrease MTLalpha2 mRNA levels which derepresses CAG1 mRNA CAG1 mRNA C. albicans orf19.6074 ORF HBR1 CAL0005189 PMID: 21372131|CGD_REF: CAL0141751 heterozygous diploid, classical genetics null HBR1/hbr1 BWP17 RNA accumulation: increased heterozygous mutant is haploinsufficient for MTLalpha2 expression CAG1 mRNA (derepression due to the absence of MTLalpha2 protein) C. albicans orf19.6074 ORF HBR1 CAL0005189 PMID: 21372131|CGD_REF: CAL0141751 heterozygous diploid, classical genetics null HBR1/hbr1 BWP17 RNA accumulation: absent +Met (repressing condition) MTLalpha2 mRNA C. albicans orf19.6074 ORF HBR1 CAL0005189 PMID: 21372131|CGD_REF: CAL0141751 heterozygous diploid, classical genetics repressible HBR1/MET3(p)-HBR1(G19S) (P-loop mutation, phenotype also observed for allele (K22Q)) BWP17 RNA accumulation: absent +Met and -Met (repressing and non-repressing conditions) MTLalpha2 mRNA C. albicans orf19.6074 ORF HBR1 CAL0005189 PMID: 21372131|CGD_REF: CAL0141751 heterozygous diploid, classical genetics repressible HBR1/MET3(p)-HBR1 BWP17 RNA accumulation: increased +Met and -Met (repressing and non-repressing conditions) CAG1 mRNA C. albicans orf19.6075 ORF CAL0005191 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.6076 ORF CAL0005193 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.6077 ORF CAL0005194 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 invasive growth: decreased solid SLAD media C. albicans orf19.6081 ORF PHR2 CAL0005209 PMID: 9315654|CGD_REF: CAL0081715 homozygous diploid, classical genetics null Not recorded vegetative growth: decreased rate acidic pH C. albicans orf19.6081 ORF PHR2 CAL0005209 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.6081 ORF PHR2 CAL0005209 PMID: 10559174|CGD_REF: CAL0081719 homozygous diploid, classical genetics null Other C. albicans viable C. albicans orf19.6081 ORF PHR2 CAL0005209 PMID: 9315654|CGD_REF: CAL0081715 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.6081 ORF PHR2 CAL0005209 PMID: 10559174|CGD_REF: CAL0081719 homozygous diploid, classical genetics null Other C. albicans cell wall morphology: abnormal increased cell-wall chitin-linked glucosylated mannoprotein fraction; severely decreased synthesis of cell-wall beta-1,6-glucan C. albicans orf19.6081 ORF PHR2 CAL0005209 PMID: 9315654|CGD_REF: CAL0081715 homozygous diploid, classical genetics null Not recorded cellular morphology: abnormal abnormal morphology of both yeast-form cells and germ tubes at alkaline pH C. albicans orf19.6081 ORF PHR2 CAL0005209 PMID: 14507372|CGD_REF: CAL0088818 heterozygous diploid, large-scale survey (large-scale identification of essential genes by gene replacement and conditional expression (GRACE) method) repressible CAI-4 inviable one allele is deleted and the other is placed under repressible Tet promoter C. albicans orf19.6081 ORF PHR2 CAL0005209 PMID: 16652171|CGD_REF: CAL0115929 homozygous diploid, classical genetics null SC5314 induction of host response: abnormal mutant elicits enhanced TNFalpha response in vitro model of infection (RAW264.7 or mouse bone marrow derived macrophages) C. albicans orf19.6081 ORF PHR2 CAL0005209 PMID: 9632601|CGD_REF: CAL0081716 homozygous diploid, classical genetics null Not recorded virulence: normal mouse intravenous infection C. albicans orf19.6081 ORF PHR2 CAL0005209 PMID: 9632601|CGD_REF: CAL0081716 heterozygous diploid, classical genetics null Not recorded virulence: decreased virulence is intermediate between that of the homozygous null mutant and wild type rat vaginal infection C. albicans orf19.6081 ORF PHR2 CAL0005209 PMID: 21135205|CGD_REF: CAL0139967 heterozygous diploid, competitive growth (large-scale identification of genes essential for virulence in mouse) repressible CAI-4 virulence: normal mouse intravenous infection C. albicans orf19.6085 ORF RPL16A CAL0005216 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.6085 ORF RPL16A CAL0005216 PMID: 12773383|CGD_REF: CAL0087974 heterozygous diploid, classical genetics (haploinsufficient phenotype assay) unspecified CAI-4 filamentous growth: decreased solid Spider medium or solid YEPD plus serum transposon insertion proximal to, but not within, the ORF C. albicans orf19.6086 ORF LEU4 CAL0005218 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.6086 ORF LEU4 CAL0005218 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, competitive growth (haploinsufficient phenotype assay, barcode deletion set) null SC5314 resistance to chemicals: decreased ergosterol analogs (ECC69 and/or ECC1384) C. albicans orf19.6090 ORF CAL0005232 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.6090 ORF CAL0005232 PMID: 21414038|CGD_REF: CAL0141808 homozygous diploid, classical genetics null BWP17 viable C. albicans orf19.6091 ORF RIM8 CAL0005233 PMID: 12819929|CGD_REF: CAL0081778 homozygous diploid, classical genetics null Not recorded vegetative growth: decreased rate alkaline pH C. albicans orf19.6091 ORF RIM8 CAL0005233 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.6091 ORF RIM8 CAL0005233 PMID: 11810234|CGD_REF: CAL0081756 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.6091 ORF RIM8 CAL0005233 PMID: 11810234|CGD_REF: CAL0081756 homozygous diploid, classical genetics null Not recorded hyphal growth: absent M199 or serum-containing media C. albicans orf19.6091 ORF RIM8 CAL0005233 PMID: 10601209|CGD_REF: CAL0081188 homozygous diploid, classical genetics null rim8::hisG/rim8::hisG-URA3-hisG CAI-4 entry into G0 (stationary phase): abnormal multibudded cells at stationary phase C. albicans orf19.6091 ORF RIM8 CAL0005233 PMID: 10601209|CGD_REF: CAL0081188 homozygous diploid, classical genetics null rim8::hisG/rim8::hisG-URA3-hisG CAI-4 filamentous growth: abnormal liquid M199 at pH 7.5 chains of yeast-form cells form C. albicans orf19.6091 ORF RIM8 CAL0005233 PMID: 10601209|CGD_REF: CAL0081188 homozygous diploid, classical genetics null rim8::hisG/rim8::hisG-URA3-hisG CAI-4 filamentous growth: absent solid serum-containing medium or solid M199 at pH 7.5 C. albicans orf19.6091 ORF RIM8 CAL0005233 PMID: 10601209|CGD_REF: CAL0081188 homozygous diploid, classical genetics null rim8::hisG/rim8::hisG-URA3-hisG CAI-4 filamentous growth: decreased solid Spider or Lee's media C. albicans orf19.6091 ORF RIM8 CAL0005233 PMID: 10601209|CGD_REF: CAL0081188 heterozygous diploid, classical genetics null rim8::hisG/rim8::hisG-URA3-hisG CAI-4 germ tube formation: normal liquid media C. albicans orf19.6091 ORF RIM8 CAL0005233 PMID: 10601209|CGD_REF: CAL0081188 homozygous diploid, classical genetics null rim8::hisG/rim8::hisG-URA3-hisG CAI-4 germ tube formation: normal liquid Spider, Lee's, or serum-containing media at 37 deg C C. albicans orf19.6091 ORF RIM8 CAL0005233 PMID: 10601209|CGD_REF: CAL0081188 heterozygous diploid, classical genetics null rim8::hisG/rim8::hisG-URA3-hisG CAI-4 hyphal growth: decreased solid serum-containing medium C. albicans orf19.6091 ORF RIM8 CAL0005233 PMID: 10601209|CGD_REF: CAL0081188 homozygous diploid, classical genetics null rim8::hisG/rim8::hisG-URA3-hisG CAI-4 invasive growth: absent solid serum-containing medium C. albicans orf19.6091 ORF RIM8 CAL0005233 PMID: 10601209|CGD_REF: CAL0081188 homozygous diploid, classical genetics null rim8::hisG/rim8::hisG-URA3-hisG CAI-4 vegetative growth: decreased rate pH 4 or 7 C. albicans orf19.6091 ORF RIM8 CAL0005233 PMID: 10601209|CGD_REF: CAL0081188 heterozygous diploid, classical genetics null rim8::hisG/rim8::hisG-URA3-hisG CAI-4 viable C. albicans orf19.6091 ORF RIM8 CAL0005233 PMID: 10601209|CGD_REF: CAL0081188 homozygous diploid, classical genetics null rim8::hisG/rim8::hisG-URA3-hisG CAI-4 viable C. albicans orf19.6091 ORF RIM8 CAL0005233 PMID: 10629054|CGD_REF: CAL0081720 homozygous diploid, classical genetics null rim8::URA3/rim8::ARG4 BWP17 hyphal growth: absent alkaline pH C. albicans orf19.6091 ORF RIM8 CAL0005233 PMID: 10629054|CGD_REF: CAL0081720 homozygous diploid, classical genetics null rim8::URA3/rim8::ARG4 BWP17 viable C. albicans orf19.6091 ORF RIM8 CAL0005233 PMID: 14507372|CGD_REF: CAL0088818 heterozygous diploid, large-scale survey (large-scale identification of essential genes by gene replacement and conditional expression (GRACE) method) repressible CAI-4 inviable one allele is deleted and the other is placed under repressible Tet promoter C. albicans orf19.6091 ORF RIM8 CAL0005233 PMID: 10992507|CGD_REF: CAL0081776 homozygous diploid, classical genetics null Not recorded virulence: decreased endothelial cells decreased capacity to damage cells in vitro model of infection C. albicans orf19.6091 ORF RIM8 CAL0005233 PMID: 10992507|CGD_REF: CAL0081776 homozygous diploid, classical genetics null Not recorded virulence: decreased decreased kidney colonization late in infection mouse intravenous infection C. albicans orf19.6091 ORF RIM8 CAL0005233 PMID: 10992507|CGD_REF: CAL0081776 homozygous diploid, classical genetics null Not recorded virulence: decreased mouse intravenous infection C. albicans orf19.6091 ORF RIM8 CAL0005233 PMID: 10992507|CGD_REF: CAL0081776 heterozygous diploid, classical genetics null Not recorded virulence: normal mouse intravenous infection C. albicans orf19.6091 ORF RIM8 CAL0005233 PMID: 20375342|CGD_REF: CAL0125177 homozygous diploid, classical genetics null BWP17 filamentous growth: decreased solid M199 medium pH 7.3 or 8.0 C. albicans orf19.6091 ORF RIM8 CAL0005233 PMID: 20375342|CGD_REF: CAL0125177 homozygous diploid, classical genetics null BWP17 virulence: decreased BALB/C mice mouse corneal infection C. albicans orf19.6091 ORF RIM8 CAL0005233 PMID: 20375342|CGD_REF: CAL0125177 homozygous diploid, classical genetics null BWP17 invasive growth: decreased porcine corneal tissue depth of hyphal penetration into corneal tissue is reduced ex vivo model of infection C. albicans orf19.6092 ORF KEL1 CAL0005234 PMID: 14500538|CGD_REF: CAL0081606 homozygous diploid, classical genetics null Not recorded viable liquid YPD at 37 deg C wild-type growth rate C. albicans orf19.6092 ORF KEL1 CAL0005234 PMID: 14500538|CGD_REF: CAL0081606 homozygous diploid, classical genetics null Not recorded adhesion: normal adhesion to human buccal epithelial cells C. albicans orf19.6092 ORF KEL1 CAL0005234 PMID: 14500538|CGD_REF: CAL0081606 homozygous diploid, classical genetics null CAI-4 filamentous growth: abnormal solid M199 or Spider media reduced filamentation ratio of colonies C. albicans orf19.6092 ORF KEL1 CAL0005234 PMID: 14500538|CGD_REF: CAL0081606 homozygous diploid, classical genetics null Not recorded virulence: normal mouse intravenous infection C. albicans orf19.6094 ORF VPS53 CAL0005237 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.6096 ORF TRP1 CAF0006885 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.6096 ORF TRP1 CAF0006885 PMID: 7958943|CGD_REF: CAL0081993 heterozygous diploid, classical genetics null Not recorded viable C. albicans orf19.6096 ORF TRP1 CAF0006885 PMID: 7958943|CGD_REF: CAL0081993 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.6096 ORF TRP1 CAF0006885 PMID: 7958943|CGD_REF: CAL0081993 homozygous diploid, classical genetics null Not recorded auxotrophy tryptophan C. albicans orf19.6096 ORF TRP1 CAF0006885 PMID: 20141603|CGD_REF: CAL0124951 homozygous diploid, systematic mutation set (homozygous insertion mutants generated with URA3-ARG4-URA3 (UAU1) cassette) null BWP17 auxotrophy tryptophan C. albicans orf19.6096 ORF TRP1 CAF0006885 PMID: 20141603|CGD_REF: CAL0124951 homozygous diploid, systematic mutation set (homozygous insertion mutants generated with URA3-ARG4-URA3 (UAU1) cassette) null BWP17 viable C. albicans orf19.6099 ORF CCT8 CAL0005242 PMID: 9846730|CGD_REF: CAL0080836 heterozygous diploid, classical genetics overexpression CAI-4 germ tube formation: delayed GlcNAc-containing liquid medium or serum-containing solid media C. albicans orf19.6099 ORF CCT8 CAL0005242 PMID: 9846730|CGD_REF: CAL0080836 heterozygous diploid, classical genetics overexpression CAI-4 germ tube formation: absent solid Spider medium C. albicans orf19.6099 ORF CCT8 CAL0005242 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.6099 ORF CCT8 CAL0005242 PMID: 9846730|CGD_REF: CAL0080836 heterozygous diploid, classical genetics null CAI-4 hyphal growth: normal solid or liquid serum-containing media C. albicans orf19.6099 ORF CCT8 CAL0005242 PMID: 9846730|CGD_REF: CAL0080836 heterozygous diploid, classical genetics null CAI-4 hyphal growth: absent solid Spider medium C. albicans orf19.6099 ORF CCT8 CAL0005242 PMID: 9846730|CGD_REF: CAL0080836 heterozygous diploid, classical genetics overexpression CAI-4 hyphal growth: absent solid Spider medium C. albicans orf19.6099 ORF CCT8 CAL0005242 PMID: 14507372|CGD_REF: CAL0088818 heterozygous diploid, large-scale survey (large-scale identification of essential genes by gene replacement and conditional expression (GRACE) method) repressible CAI-4 inviable one allele is deleted and the other is placed under repressible Tet promoter C. albicans orf19.6099 ORF CCT8 CAL0005242 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, competitive growth (haploinsufficient phenotype assay, barcode deletion set) null SC5314 resistance to chemicals: decreased cytochalasin D C. albicans orf19.6099 ORF CCT8 CAL0005242 PMID: 9846730|CGD_REF: CAL0080836 unknown ploidy, classical genetics overexpression Other C. albicans viable C. albicans orf19.6099 ORF CCT8 CAL0005242 PMID: 9846730|CGD_REF: CAL0080836 homozygous diploid, classical genetics null CAI-4 inviable homozygous null mutant strain could not be recovered, suggesting that the gene is essential under the selection conditions C. albicans orf19.6099 ORF CCT8 CAL0005242 PMID: 9846730|CGD_REF: CAL0080836 heterozygous diploid, classical genetics null CAI-4 viable C. albicans orf19.6099 ORF CCT8 CAL0005242 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 invasive growth: decreased solid SLAD media C. albicans orf19.610 ORF EFG1 CAL0000906 PMID: 19188358|CGD_REF: CAL0122313 homozygous diploid, classical genetics null Not recorded germ tube formation: absent arginine- or urea-containing media or 5% carbon dioxide C. albicans orf19.610 ORF EFG1 CAL0000906 PMID: 16467475|CGD_REF: CAL0115509 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased Calcofluor White C. albicans orf19.610 ORF EFG1 CAL0000906 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.610 ORF EFG1 CAL0000906 PMID: 10456912|CGD_REF: CAL0081187 homozygous diploid, classical genetics null CAI-4 viable HLC52 derivative of CAI4; no opaque-like phenotype observed in this background, unlike the SS4 strain background C. albicans orf19.610 ORF EFG1 CAL0000906 PMID: 10456912|CGD_REF: CAL0081187 heterozygous diploid, classical genetics overexpression Not recorded viable C. albicans orf19.610 ORF EFG1 CAL0000906 PMID: 11533231|CGD_REF: CAL0080743 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.610 ORF EFG1 CAL0000906 PMID: 12374745|CGD_REF: CAL0080781 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.610 ORF EFG1 CAL0000906 PMID: 12798685|CGD_REF: CAL0081196 heterozygous diploid, classical genetics overexpression CAI-4 viable C. albicans orf19.610 ORF EFG1 CAL0000906 PMID: 12798685|CGD_REF: CAL0081196 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.610 ORF EFG1 CAL0000906 PMID: 14665461|CGD_REF: CAL0081156 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.610 ORF EFG1 CAL0000906 PMID: 17880264|CGD_REF: CAL0118619 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.610 ORF EFG1 CAL0000906 PMID: 9155024|CGD_REF: CAL0081185 heterozygous diploid, classical genetics null Not recorded viable C. albicans orf19.610 ORF EFG1 CAL0000906 PMID: 14665461|CGD_REF: CAL0081156 homozygous diploid, classical genetics null Not recorded adhesion: decreased adhesion to human embryonic kidney cells C. albicans orf19.610 ORF EFG1 CAL0000906 PMID: 15760450|CGD_REF: CAL0104038 homozygous diploid, classical genetics null Not recorded adhesion: decreased adhesion to FaDu or OKF6/TERT-2 epithelial cells C. albicans orf19.610 ORF EFG1 CAL0000906 PMID: 16487333|CGD_REF: CAL0115574 homozygous diploid, classical genetics null Not recorded adhesion: decreased adhesion to extracellular matrices C. albicans orf19.610 ORF EFG1 CAL0000906 PMID: 15760450|CGD_REF: CAL0104038 heterozygous diploid, classical genetics null CAI-4 hyphal growth: normal FaDu or OKF6/TERT-2 epithelial cells reintegrant in vitro model of infection C. albicans orf19.610 ORF EFG1 CAL0000906 PMID: 15760450|CGD_REF: CAL0104038 homozygous diploid, classical genetics null CAI-4 hyphal growth: absent FaDu or OKF6/TERT-2 epithelial cells short pseudohyphae are observed, but no hyphae in vitro model of infection C. albicans orf19.610 ORF EFG1 CAL0000906 PMID: 9155024|CGD_REF: CAL0081185 heterozygous diploid, classical genetics repressible CAI-8 hyphal growth: decreased pseudohyphal growth is increased C. albicans orf19.610 ORF EFG1 CAL0000906 PMID: 11533231|CGD_REF: CAL0080743 homozygous diploid, classical genetics null Not recorded hyphal growth: absent solid SSA medium C. albicans orf19.610 ORF EFG1 CAL0000906 PMID: 11595734|CGD_REF: CAL0081060 homozygous diploid, classical genetics null Not recorded hyphal growth: abnormal YPD plus serum or Lee's media C. albicans orf19.610 ORF EFG1 CAL0000906 PMID: 15218092|CGD_REF: CAL0081199 homozygous diploid, classical genetics null CAI-4 hyphal growth: absent microaerophilic conditions C. albicans orf19.610 ORF EFG1 CAL0000906 PMID: 18547332|CGD_REF: CAL0119100 homozygous diploid, classical genetics null CAF2-1 hyphal growth: absent iron deprivation C. albicans orf19.610 ORF EFG1 CAL0000906 PMID: 10692363|CGD_REF: CAL0081189 homozygous diploid, classical genetics null efg1::hisG/efg1::CAT-URA3-CAT WO-1 phenotypic switching: absent opaque-to-white switching is not observed, apparently because of the inability to attain white-phase cell type C. albicans orf19.610 ORF EFG1 CAL0000906 PMID: 10692363|CGD_REF: CAL0081189 homozygous diploid, classical genetics null efg1::hisG/efg1::CAT-URA3-CAT WO-1 viable C. albicans orf19.610 ORF EFG1 CAL0000906 PMID: 10865906|CGD_REF: CAL0081191 homozygous diploid, classical genetics null efg1::hisG/efg1::hisG CAI-4 virulence: abnormal reconstituted human intestinal epithelium, Caco-2 cells decreased migration across cell monolayer ex vivo model of infection C. albicans orf19.610 ORF EFG1 CAL0000906 PMID: 10692363|CGD_REF: CAL0081189 heterozygous diploid, classical genetics null efg1::hisG-URA3-hisG/EFG1 WO-1 phenotypic switching: decreased opaque-to-white switching C. albicans orf19.610 ORF EFG1 CAL0000906 PMID: 10692363|CGD_REF: CAL0081189 heterozygous diploid, classical genetics null efg1::hisG-URA3-hisG/EFG1 WO-1 viable C. albicans orf19.610 ORF EFG1 CAL0000906 PMID: 11290709|CGD_REF: CAL0080977 heterozygous diploid, classical genetics reduction of function efg1-T206A Not recorded hyphal growth: decreased solid Spider medium, liquid Lee's or GlcNAc-containing medium C. albicans orf19.610 ORF EFG1 CAL0000906 PMID: 11290709|CGD_REF: CAL0080977 heterozygous diploid, classical genetics activation efg1-T206E Not recorded filamentous growth: decreased GlcNAc-containing medium C. albicans orf19.610 ORF EFG1 CAL0000906 PMID: 11290709|CGD_REF: CAL0080977 heterozygous diploid, classical genetics activation efg1-T206E Not recorded filamentous growth: normal serum-containing medium C. albicans orf19.610 ORF EFG1 CAL0000906 PMID: 11290709|CGD_REF: CAL0080977 heterozygous diploid, classical genetics activation efg1-T206E Not recorded filamentous growth: increased solid or liquid Spider medium C. albicans orf19.610 ORF EFG1 CAL0000906 PMID: 18547332|CGD_REF: CAL0119100 homozygous diploid, classical genetics null CAF2-1 biofilm formation: decreased C. albicans orf19.610 ORF EFG1 CAL0000906 PMID: 20041210|CGD_REF: CAL0124764 homozygous diploid, systematic mutation set null SN152 invasive growth: decreased YEPD medium at 37 deg C strongly decreased C. albicans orf19.610 ORF EFG1 CAL0000906 PMID: 15218092|CGD_REF: CAL0081199 homozygous diploid, classical genetics null Not recorded cell shape: abnormal cells are rod-shaped C. albicans orf19.610 ORF EFG1 CAL0000906 PMID: 16980403|CGD_REF: CAL0116783 homozygous diploid, classical genetics null Not recorded chemical compound accumulation: normal tyrosol tyrosol production is essentially wild-type, but mutant does not show the time-dependent plateau in tyrosol level that is observed in wild type or cph1 homozygous null mutant C. albicans orf19.610 ORF EFG1 CAL0000906 PMID: 10496941|CGD_REF: CAL0080973 homozygous diploid, classical genetics null Not recorded chlamydospore formation: absent phenotype is observed for the null,T206A, and T206E mutants C. albicans orf19.610 ORF EFG1 CAL0000906 PMID: 10456912|CGD_REF: CAL0081187 homozygous diploid, classical genetics null Not recorded inviable homozygous null mutant strain could not be recovered, suggesting that the gene is essential under the selection conditions C. albicans orf19.610 ORF EFG1 CAL0000906 PMID: 15218092|CGD_REF: CAL0081199 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased antimycin A C. albicans orf19.610 ORF EFG1 CAL0000906 PMID: 20041210|CGD_REF: CAL0124764 homozygous diploid, systematic mutation set null SN152 colony appearance: abnormal Spider medium smooth colonies with no peripheral filamentation C. albicans orf19.610 ORF EFG1 CAL0000906 PMID: 10456912|CGD_REF: CAL0081187 heterozygous diploid, classical genetics repressible SC5314 phenotypic switching: abnormal opaque-like phenotype is produced in a strain background not known to undergo white-opaque switching C. albicans orf19.610 ORF EFG1 CAL0000906 PMID: 10456912|CGD_REF: CAL0081187 heterozygous diploid, classical genetics overexpression WO-1 phenotypic switching: increased opaque-to-white switching C. albicans orf19.610 ORF EFG1 CAL0000906 PMID: 17880264|CGD_REF: CAL0118619 homozygous diploid, classical genetics null Not recorded phenotypic switching: decreased MTLa/MTLa background opaque-to-white switching C. albicans orf19.610 ORF EFG1 CAL0000906 PMID: 17880264|CGD_REF: CAL0118619 homozygous diploid, classical genetics null Not recorded phenotypic switching: increased MTLa/MTLa background; phenotype not observed in MTLa/MTLalpha white-to-opaque switching C. albicans orf19.610 ORF EFG1 CAL0000906 PMID: 16039996|CGD_REF: CAL0114588 homozygous diploid, classical genetics null Not recorded pseudohyphal growth: decreased defect in pseudohyphal growth after prolonged (16 h) incubation with macrophages, at which point there is significant macrophage lysis C. albicans orf19.610 ORF EFG1 CAL0000906 PMID: 16487333|CGD_REF: CAL0115574 homozygous diploid, classical genetics null CAI-4 filamentous growth: decreased decreased invasion of artificial extracellular matrices C. albicans orf19.610 ORF EFG1 CAL0000906 PMID: 16267276|CGD_REF: CAL0115298 homozygous diploid, classical genetics null CAI-4 filamentous growth: increased embedded in YPS agar, 25 deg C exhibits microaerophilic growth C. albicans orf19.610 ORF EFG1 CAL0000906 PMID: 9155024|CGD_REF: CAL0081185 heterozygous diploid, classical genetics overexpression CAI-8 filamentous growth: increased both inducing and noninducing conditions hyperfilamentation (both hyphae and pseudohyphae) C. albicans orf19.610 ORF EFG1 CAL0000906 PMID: 11290709|CGD_REF: CAL0080977 heterozygous diploid, classical genetics overexpression Not recorded filamentous growth: abnormal SCAA medium hyperfilamentation and pseudohyphal growth observed C. albicans orf19.610 ORF EFG1 CAL0000906 PMID: 12374745|CGD_REF: CAL0080781 homozygous diploid, classical genetics null Not recorded resistance to chemicals: increased 3-aminotriazole C. albicans orf19.610 ORF EFG1 CAL0000906 PMID: 16467475|CGD_REF: CAL0115509 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased Congo Red C. albicans orf19.610 ORF EFG1 CAL0000906 PMID: 15728931|CGD_REF: CAL0082215 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased triazoles C. albicans orf19.610 ORF EFG1 CAL0000906 PMID: 10816502|CGD_REF: CAL0081036 homozygous diploid, classical genetics null efg1::hisG/egf1::hisG-URA3-hisG CAI-4 resistance to phagocytosis: increased reduced endocytosis in vitro model of infection (human umbilical cord vein endothelial cells) C. albicans orf19.610 ORF EFG1 CAL0000906 PMID: 12867554|CGD_REF: CAL0081071 homozygous diploid, classical genetics null CAI-4 resistance to killing by host cells: decreased in vitro model of infection (human neutrophils) C. albicans orf19.610 ORF EFG1 CAL0000906 PMID: 15813733|CGD_REF: CAL0104041 homozygous diploid, classical genetics null CAI-4 resistance to killing by host cells: decreased decreased viability in the presence of blood components in vitro model of infection (human blood) C. albicans orf19.610 ORF EFG1 CAL0000906 PMID: 21407800|CGD_REF: CAL0141800 homozygous diploid, classical genetics null BWP17 interaction with host/environment: abnormal severely reduced invasion, and significantly reduced adhesion and damage to epithelial cells ex vivo model of infection C. albicans orf19.610 ORF EFG1 CAL0000906 PMID: 21512583|CGD_REF: CAL0141906 homozygous diploid, classical genetics null SC5314 RNA accumulation: decreased DEF1/EED1 promoter contains several E box motifs that resemble binding sites of Efg1 UME6 mRNA C. albicans orf19.610 ORF EFG1 CAL0000906 PMID: 22037180|CGD_REF: CAL0000143564 homozygous diploid, classical genetics null efg1::hisG/efg1::hisG CAI-4 RNA accumulation: decreased ALS1 mRNA C. albicans orf19.610 ORF EFG1 CAL0000906 PMID: 22037180|CGD_REF: CAL0000143564 homozygous diploid, classical genetics null efg1::hisG/efg1::hisG CAI-4 flocculation: decreased decreased caspofungin-induced flocculation C. albicans orf19.610 ORF EFG1 CAL0000906 PMID: 22037180|CGD_REF: CAL0000143564 homozygous diploid, classical genetics null efg1::hisG/efg1::hisG CAI-4 resistance to chemicals: decreased caspofungin C. albicans orf19.610 ORF EFG1 CAL0000906 PMID: 22265407|CGD_REF: CAL0000143925 homozygous diploid, classical genetics null Other C. albicans biofilm formation: decreased C. albicans orf19.610 ORF EFG1 CAL0000906 PMID: 22422573|CGD_REF: CAL0000156983 homozygous diploid, classical genetics null CAF2-1 resistance to chemicals: decreased miconazole efg1 sessile cells showed increased sensitivity to miconazole (BEC50 =0.1 mM) as compared to sessile cells of the corresponding isogenic WT strain CAF2 (BEC50 > 4.8 mM) C. albicans orf19.610 ORF EFG1 CAL0000906 PMID: 22422573|CGD_REF: CAL0000156983 homozygous diploid, classical genetics null CAF2-1 chemical compound accumulation: increased intracellular miconazole significant increase in intracellular miconazole levels in efg1 sessile cells as compared to WT cells following miconazole treatment C. albicans orf19.610 ORF EFG1 CAL0000906 PMID: 22422573|CGD_REF: CAL0000156983 homozygous diploid, classical genetics null CAF2-1 resistance to chemicals: normal miconazole the efg1 mutant displayed no increased miconazole sensitivity as compared to WT cells in biofilms in vivo other model (subcutaneous biofilm rat model) C. albicans orf19.610 ORF EFG1 CAL0000906 PMID: 16980403|CGD_REF: CAL0116783 homozygous diploid, classical genetics null SC5314 biofilm formation: abnormal defect in filamentous growth in biofilm, and yeast-form biofilm cells do not respond to tyrosol C. albicans orf19.610 ORF EFG1 CAL0000906 PMID: 22923045|CGD_REF: CAL0000157829 homozygous diploid, competitive growth null Other C. albicans formation of anatomical structure: absent elevated concentrations of CO2 at 37 deg finger structure C. albicans orf19.610 ORF EFG1 CAL0000906 PMID: 19666778|CGD_REF: CAL0123941 homozygous diploid, classical genetics null Not recorded virulence: decreased C. elegans infection C. albicans orf19.610 ORF EFG1 CAL0000906 PMID: 12867554|CGD_REF: CAL0081071 homozygous diploid, classical genetics null Not recorded virulence: decreased human oral epithelial cells decreased capacity to damage cells in vitro model of infection C. albicans orf19.610 ORF EFG1 CAL0000906 PMID: 15760450|CGD_REF: CAL0104038 homozygous diploid, classical genetics null Not recorded virulence: decreased FaDu or OKF6/TERT-2 epithelial cells decreased capacity to damage cells in vitro model of infection C. albicans orf19.610 ORF EFG1 CAL0000906 PMID: 12381467|CGD_REF: CAL0087147 homozygous diploid, classical genetics null Not recorded virulence: decreased Galleria mellonella (Greater Wax Moth) larvae insect infection C. albicans orf19.610 ORF EFG1 CAL0000906 PMID: 16518764|CGD_REF: CAL0115737 homozygous diploid, classical genetics null Not recorded virulence: decreased insect infection C. albicans orf19.610 ORF EFG1 CAL0000906 PMID: 15760450|CGD_REF: CAL0104038 heterozygous diploid, classical genetics null Not recorded virulence: decreased virulence is intermediate between that of the homozygous null mutant and wild type mouse intravenous infection C. albicans orf19.610 ORF EFG1 CAL0000906 PMID: 15760450|CGD_REF: CAL0104038 homozygous diploid, classical genetics null Not recorded virulence: decreased mouse intravenous infection C. albicans orf19.610 ORF EFG1 CAL0000906 PMID: 15760450|CGD_REF: CAL0104038 homozygous diploid, classical genetics null Not recorded virulence: decreased mouse oropharyngeal infection C. albicans orf19.610 ORF EFG1 CAL0000906 PMID: 15760450|CGD_REF: CAL0104038 heterozygous diploid, classical genetics null Not recorded virulence: normal mouse oropharyngeal infection C. albicans orf19.610 ORF EFG1 CAL0000906 PMID: 20491944|CGD_REF: CAL0125652 homozygous diploid, classical genetics null CAF2-1 resistance to chemicals: decreased fluconazole C. albicans orf19.610 ORF EFG1 CAL0000906 PMID: 20491944|CGD_REF: CAL0125652 homozygous diploid, classical genetics null CAF2-1 resistance to chemicals: decreased itraconazole C. albicans orf19.610 ORF EFG1 CAL0000906 PMID: 20491944|CGD_REF: CAL0125652 homozygous diploid, classical genetics null CAF2-1 resistance to chemicals: decreased ketoconazole C. albicans orf19.610 ORF EFG1 CAL0000906 PMID: 20491944|CGD_REF: CAL0125652 homozygous diploid, classical genetics null CAF2-1 resistance to chemicals: decreased nystatin C. albicans orf19.610 ORF EFG1 CAL0000906 PMID: 20491944|CGD_REF: CAL0125652 homozygous diploid, classical genetics null CAF2-1 resistance to chemicals: decreased amphotericin B C. albicans orf19.6100 ORF CAL0005934 PMID: 14663094|CGD_REF: CAL0080633 homozygous diploid, systematic mutation set (homozygous insertion mutants generated with URA3-ARG4-URA3 (UAU1) cassette) null BWP17 viable C. albicans orf19.6100 ORF CAL0005934 PMID: 23856128|CGD_REF: CAL0000172540 homozygous diploid, classical genetics null BWP17 resistance to chemicals: decreased propolis C. albicans orf19.6102 ORF RCA1 CAL0005936 PMID: 20041210|CGD_REF: CAL0124764 homozygous diploid, systematic mutation set null SN152 vegetative growth: decreased YEPD, SD, or Lee's pH 4.5 media at 30 deg C strongly decreased C. albicans orf19.6102 ORF RCA1 CAL0005936 PMID: 20041210|CGD_REF: CAL0124764 homozygous diploid, systematic mutation set null SN152 invasive growth: increased YEPD medium at 30 deg C strongly increased C. albicans orf19.6102 ORF RCA1 CAL0005936 PMID: 20041210|CGD_REF: CAL0124764 homozygous diploid, systematic mutation set null SN152 colony appearance: abnormal Spider medium at 30 deg C strongly increased colony fuzziness and/or peripheral filamentation C. albicans orf19.6102 ORF RCA1 CAL0005936 PMID: 22253597|CGD_REF: CAL0000143883 homozygous diploid, classical genetics null CAI-4 vegetative growth: decreased rate 77% increase of generation time C. albicans orf19.6102 ORF RCA1 CAL0005936 PMID: 22581526|CGD_REF: CAL0000157314 homozygous diploid, systematic mutation set null BWP17 resistance to chemicals: decreased flucytosine C. albicans orf19.6102 ORF RCA1 CAL0005936 PMID: 22581526|CGD_REF: CAL0000157314 homozygous diploid, systematic mutation set null BWP17 resistance to chemicals: increased fluconazole C. albicans orf19.6102 ORF RCA1 CAL0005936 PMID: 22253597|CGD_REF: CAL0000143883 homozygous diploid, classical genetics null CAI-4 viable C. albicans orf19.6102 ORF RCA1 CAL0005936 PMID: 22253597|CGD_REF: CAL0000143883 homozygous diploid, classical genetics null CAI-4 resistance to chemicals: decreased Congo Red C. albicans orf19.6102 ORF RCA1 CAL0005936 PMID: 22253597|CGD_REF: CAL0000143883 homozygous diploid, classical genetics null CAI-4 resistance to chemicals: decreased caffeine C. albicans orf19.6102 ORF RCA1 CAL0005936 PMID: 22253597|CGD_REF: CAL0000143883 homozygous diploid, classical genetics null CAI-4 resistance to chemicals: decreased sodium dodecyl sulfate C. albicans orf19.6102 ORF RCA1 CAL0005936 PMID: 22253597|CGD_REF: CAL0000143883 homozygous diploid, classical genetics null CAI-4 filamentous growth: decreased in response to serum C. albicans orf19.6102 ORF RCA1 CAL0005936 PMID: 22581526|CGD_REF: CAL0000157314 homozygous diploid, systematic mutation set null BWP17 resistance to chemicals: increased caspofungin C. albicans orf19.6105 ORF MVD CAL0005938 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.6105 ORF MVD CAL0005938 PMID: 21135205|CGD_REF: CAL0139967 heterozygous diploid, large-scale survey (large-scale identification of genes essential for virulence in mouse) repressible CAI-4 virulence: absent mouse intravenous infection C. albicans orf19.6109 ORF TUP1 CAL0005939 PMID: 20041210|CGD_REF: CAL0124764 homozygous diploid, systematic mutation set null SN152 resistance to chemicals: decreased fluconazole severely sensitive C. albicans orf19.6109 ORF TUP1 CAL0005939 PMID: 20041210|CGD_REF: CAL0124764 homozygous diploid, systematic mutation set null SN152 ionic stress resistance: decreased lithium chloride severely sensitive C. albicans orf19.6109 ORF TUP1 CAL0005939 PMID: 9204892|CGD_REF: CAL0081053 homozygous diploid, classical genetics null Not recorded germ tube formation: decreased serum-containing or Lee's media C. albicans orf19.6109 ORF TUP1 CAL0005939 PMID: 20041210|CGD_REF: CAL0124764 homozygous diploid, systematic mutation set null SN152 resistance to chemicals: decreased flucytosine strongly sensitive C. albicans orf19.6109 ORF TUP1 CAL0005939 PMID: 9204892|CGD_REF: CAL0081053 homozygous diploid, classical genetics null Not recorded heat sensitivity: increased C. albicans orf19.6109 ORF TUP1 CAL0005939 PMID: 9204892|CGD_REF: CAL0081053 homozygous diploid, classical genetics null Not recorded vegetative growth: increased rate glycerol carbon source C. albicans orf19.6109 ORF TUP1 CAL0005939 PMID: 11737641|CGD_REF: CAL0080636 homozygous diploid, classical genetics null Not recorded vegetative growth: decreased rate C. albicans orf19.6109 ORF TUP1 CAL0005939 PMID: 11737641|CGD_REF: CAL0080636 homozygous diploid, classical genetics null Not recorded vegetative growth: decreased rate C. albicans orf19.6109 ORF TUP1 CAL0005939 PMID: 12773383|CGD_REF: CAL0087974 heterozygous diploid, classical genetics (haploinsufficient phenotype assay) null CAI-4 viable heterozygous deletion or transposon insertion C. albicans orf19.6109 ORF TUP1 CAL0005939 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.6109 ORF TUP1 CAL0005939 PMID: 11737641|CGD_REF: CAL0080636 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.6109 ORF TUP1 CAL0005939 PMID: 12060662|CGD_REF: CAL0081313 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.6109 ORF TUP1 CAL0005939 PMID: 12455984|CGD_REF: CAL0081164 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.6109 ORF TUP1 CAL0005939 PMID: 12581357|CGD_REF: CAL0081069 heterozygous diploid, classical genetics overexpression CAI-4 viable C. albicans orf19.6109 ORF TUP1 CAL0005939 PMID: 15701792|CGD_REF: CAL0082331 heterozygous diploid, classical genetics null Not recorded viable C. albicans orf19.6109 ORF TUP1 CAL0005939 PMID: 15701792|CGD_REF: CAL0082331 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.6109 ORF TUP1 CAL0005939 PMID: 16313617|CGD_REF: CAL0114226 heterozygous diploid, classical genetics null Not recorded viable C. albicans orf19.6109 ORF TUP1 CAL0005939 PMID: 16313617|CGD_REF: CAL0114226 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.6109 ORF TUP1 CAL0005939 PMID: 9204892|CGD_REF: CAL0081053 heterozygous diploid, classical genetics null Not recorded viable C. albicans orf19.6109 ORF TUP1 CAL0005939 PMID: 9204892|CGD_REF: CAL0081053 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.6109 ORF TUP1 CAL0005939 PMID: 20041210|CGD_REF: CAL0124764 homozygous diploid, systematic mutation set null SN152 resistance to chemicals: decreased rapamycin severely sensitive C. albicans orf19.6109 ORF TUP1 CAL0005939 PMID: 15209998|CGD_REF: CAL0081077 homozygous diploid, classical genetics null Not recorded adhesion: decreased adhesion to oral epithelial cells C. albicans orf19.6109 ORF TUP1 CAL0005939 PMID: 18680523|CGD_REF: CAL0119367 homozygous diploid, classical genetics null Not recorded interaction with host/environment: abnormal decreased viability during growth in co-culture with Pseudomonas aeruginosa, specific to hyphal induction media C. albicans orf19.6109 ORF TUP1 CAL0005939 PMID: 11532938|CGD_REF: CAL0080745 homozygous diploid, classical genetics null Not recorded invasive growth: increased agar invasion is constitutive C. albicans orf19.6109 ORF TUP1 CAL0005939 PMID: 20041210|CGD_REF: CAL0124764 homozygous diploid, systematic mutation set null SN152 invasive growth: increased SD or YEPD media at 30 deg C strongly increased C. albicans orf19.6109 ORF TUP1 CAL0005939 PMID: 10816502|CGD_REF: CAL0081036 homozygous diploid, classical genetics null tup1::hisG/tup1::hisG-URA3-hisG CAI-4 virulence: decreased reduced endocytosis by human umbilical cord vein endothelial cells C. albicans orf19.6109 ORF TUP1 CAL0005939 PMID: 11737641|CGD_REF: CAL0080636 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased ethanol C. albicans orf19.6109 ORF TUP1 CAL0005939 PMID: 11737641|CGD_REF: CAL0080636 homozygous diploid, classical genetics null Not recorded oxidative stress resistance: decreased hydrogen peroxide C. albicans orf19.6109 ORF TUP1 CAL0005939 PMID: 16313617|CGD_REF: CAL0114226 homozygous diploid, classical genetics null WO-1 cell shape: abnormal cells within fuzzy, frizzy, wrinkled, and smooth colonies have distinct morphologies C. albicans orf19.6109 ORF TUP1 CAL0005939 PMID: 9204892|CGD_REF: CAL0081053 homozygous diploid, classical genetics null Not recorded cell wall morphology: abnormal effect is slight C. albicans orf19.6109 ORF TUP1 CAL0005939 PMID: 16313617|CGD_REF: CAL0114226 heterozygous diploid, classical genetics null Not recorded cellular morphology: normal C. albicans orf19.6109 ORF TUP1 CAL0005939 PMID: 16313617|CGD_REF: CAL0114226 homozygous diploid, classical genetics null WO-1 mating response: abnormal MTLalpha strain mated to MTLa tester cells of smooth morphology are mating-defective, but fuzzy, frizzy, and wrinkled are mating-competent, with reduced efficiency compared to wild type C. albicans orf19.6109 ORF TUP1 CAL0005939 PMID: 16313617|CGD_REF: CAL0114226 heterozygous diploid, classical genetics null WO-1 colony appearance: normal both white and opaque cells C. albicans orf19.6109 ORF TUP1 CAL0005939 PMID: 16313617|CGD_REF: CAL0114226 homozygous diploid, classical genetics null WO-1 colony appearance: abnormal filamentous growth within fuzzy, frizzy, and wrinkled colonies C. albicans orf19.6109 ORF TUP1 CAL0005939 PMID: 20041210|CGD_REF: CAL0124764 homozygous diploid, systematic mutation set null SN152 colony appearance: abnormal multiple different media including YEPD with or without serum, Spider, Lee's, blood agar; temperatures from 30-37 deg C strongly increased colony fuzziness and/or peripheral filamentation C. albicans orf19.6109 ORF TUP1 CAL0005939 PMID: 20041210|CGD_REF: CAL0124764 homozygous diploid, systematic mutation set null SN152 colony color: abnormal CHROMagar medium at 30 and 37 deg C darker than normal C. albicans orf19.6109 ORF TUP1 CAL0005939 PMID: 12455984|CGD_REF: CAL0081164 homozygous diploid, classical genetics null Not recorded phenotypic switching: absent white-to-opaque switching C. albicans orf19.6109 ORF TUP1 CAL0005939 PMID: 11532938|CGD_REF: CAL0080745 homozygous diploid, classical genetics null Not recorded pseudohyphal growth: increased pseudohyphal growth under conditions favoring yeast-form growth of wild type C. albicans orf19.6109 ORF TUP1 CAL0005939 PMID: 20041210|CGD_REF: CAL0124764 homozygous diploid, systematic mutation set null SN152 resistance to chemicals: decreased caffeine severely sensitive C. albicans orf19.6109 ORF TUP1 CAL0005939 PMID: 18424510|CGD_REF: CAL0118975 homozygous diploid, classical genetics null Not recorded chemical compound accumulation: increased farnesol C. albicans orf19.6109 ORF TUP1 CAL0005939 PMID: 20041210|CGD_REF: CAL0124764 homozygous diploid, systematic mutation set null SN152 metal resistance: decreased copper(2+) severely sensitive C. albicans orf19.6109 ORF TUP1 CAL0005939 PMID: 12773383|CGD_REF: CAL0087974 heterozygous diploid, classical genetics (haploinsufficient phenotype assay) null CAI-4 filamentous growth: increased solid Spider medium or solid YEPD plus serum heterozygous deletion or transposon insertion C. albicans orf19.6109 ORF TUP1 CAL0005939 PMID: 15209998|CGD_REF: CAL0081077 homozygous diploid, classical genetics null SC5314 filamentous growth: abnormal in oral epithelial cell culture growth is exclusively pseudohyphal in vitro model of infection C. albicans orf19.6109 ORF TUP1 CAL0005939 PMID: 12060662|CGD_REF: CAL0081313 homozygous diploid, classical genetics null Not recorded filamentous growth: abnormal YPD medium at 30 deg C constitutive filamentous growth C. albicans orf19.6109 ORF TUP1 CAL0005939 PMID: 18424510|CGD_REF: CAL0118975 heterozygous diploid, classical genetics null CAI-4 filamentous growth: abnormal farnesol suppresses haploinsufficiency with respect to filamentation C. albicans orf19.6109 ORF TUP1 CAL0005939 PMID: 18424510|CGD_REF: CAL0118975 homozygous diploid, classical genetics null CAI-4 filamentous growth: abnormal filamentation is insensitive to farnesol C. albicans orf19.6109 ORF TUP1 CAL0005939 PMID: 9204892|CGD_REF: CAL0081053 homozygous diploid, classical genetics null CAI-4 filamentous growth: abnormal filamentous growth without induction (all conditions tested) C. albicans orf19.6109 ORF TUP1 CAL0005939 PMID: 15701792|CGD_REF: CAL0082331 homozygous diploid, classical genetics null RM1000 filamentous growth: increased solid Spider medium at 30 deg C hyperfilamentous with increased pseudohyphae and decreased peripheral hyphae C. albicans orf19.6109 ORF TUP1 CAL0005939 PMID: 15701792|CGD_REF: CAL0082331 heterozygous diploid, classical genetics null RM1000 filamentous growth: abnormal solid Spider medium at 30 deg C hyperfilamentous with increased pseudohyphae and decreased peripheral hyphae; phenotype is intermediate between that of wild type and homozygous null C. albicans orf19.6109 ORF TUP1 CAL0005939 PMID: 12455984|CGD_REF: CAL0081164 homozygous diploid, classical genetics null WO-1 filamentous growth: abnormal unidirectional morphology transitions (hyphal to pseudohyphal to budding to pseudohyphal) C. albicans orf19.6109 ORF TUP1 CAL0005939 PMID: 11532938|CGD_REF: CAL0080745 homozygous diploid, classical genetics null Not recorded filamentous growth: increased SLAD medium C. albicans orf19.6109 ORF TUP1 CAL0005939 PMID: 9204892|CGD_REF: CAL0081053 heterozygous diploid, classical genetics null CAI-4 filamentous growth: increased C. albicans orf19.6109 ORF TUP1 CAL0005939 PMID: 19057660|CGD_REF: CAL0121272 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased caspofungin filamentous cells appear to be more sensitive than yeast-form cells C. albicans orf19.6109 ORF TUP1 CAL0005939 PMID: 21407800|CGD_REF: CAL0141800 homozygous diploid, classical genetics null BWP17 interaction with host/environment: abnormal significantly reduces adhesion, invasion, and damage to epithelial cells ex vivo model of infection C. albicans orf19.6109 ORF TUP1 CAL0005939 PMID: 21512583|CGD_REF: CAL0141906 homozygous diploid, classical genetics null SC5314 RNA accumulation: increased DEF1/EED1 mRNA C. albicans orf19.6109 ORF TUP1 CAL0005939 PMID: 12576958|CGD_REF: CAL0087535 homozygous diploid, classical genetics null Not recorded virulence: decreased decreased cecal colonization and extraintestinal dissemination mouse gastrointestinal tract infection C. albicans orf19.6109 ORF TUP1 CAL0005939 PMID: 11532938|CGD_REF: CAL0080745 homozygous diploid, classical genetics null Not recorded virulence: decreased mouse intravenous infection C. albicans orf19.6109 ORF TUP1 CAL0005939 PMID: 12576958|CGD_REF: CAL0087535 homozygous diploid, classical genetics null Not recorded virulence: absent mouse intravenous infection C. albicans orf19.6109 ORF TUP1 CAL0005939 PMID: 19197361|CGD_REF: CAL0122318 homozygous diploid, classical genetics null SC5314 resistance to chemicals: decreased rapamycin (2 nM) C. albicans orf19.6121 ORF MNL1 CAL0005981 PMID: 20041210|CGD_REF: CAL0124764 homozygous diploid, systematic mutation set null SN152 resistance to chemicals: increased fluconazole strongly resistant C. albicans orf19.6121 ORF MNL1 CAL0005981 PMID: 15470239|CGD_REF: CAL0082146 homozygous diploid, classical genetics null Not recorded viable no apparent phenotype C. albicans orf19.6121 ORF MNL1 CAL0005981 PMID: 15470239|CGD_REF: CAL0082146 heterozygous diploid, classical genetics overexpression Not recorded viable no apparent stress-related phenotype C. albicans orf19.6121 ORF MNL1 CAL0005981 PMID: 18653474|CGD_REF: CAL0119352 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased weak organic acids highest sensitivity to one- and two-carbon weak acids (formic and acetic), lesser sensitivity to 4- and 6-carbon weak acids (butyric and sorbic) and to the aromatic weak acid benzoic acid C. albicans orf19.6121 ORF MNL1 CAL0005981 PMID: 23856128|CGD_REF: CAL0000172540 homozygous diploid, classical genetics null BWP17 resistance to chemicals: decreased propolis C. albicans orf19.6124 ORF ACE2 CAL0005982 PMID: 20041210|CGD_REF: CAL0124764 homozygous diploid, systematic mutation set null SN152 resistance to chemicals: increased Calcofluor White strongly resistant C. albicans orf19.6124 ORF ACE2 CAL0005982 PMID: 16507592|CGD_REF: CAL0115695 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.6124 ORF ACE2 CAL0005982 PMID: 15255906|CGD_REF: CAL0082068 homozygous diploid, classical genetics null SC5314 invasive growth: increased YEPD agar at 30 deg C C. albicans orf19.6124 ORF ACE2 CAL0005982 PMID: 20041210|CGD_REF: CAL0124764 homozygous diploid, systematic mutation set null SN152 invasive growth: increased YEPD medium at 30 deg C strongly increased C. albicans orf19.6124 ORF ACE2 CAL0005982 PMID: 16998073|CGD_REF: CAL0117037 homozygous diploid, classical genetics null Not recorded resistance to chemicals: increased antimycin A C. albicans orf19.6124 ORF ACE2 CAL0005982 PMID: 15255906|CGD_REF: CAL0082068 homozygous diploid, classical genetics null SC5314 filamentous growth: increased hyperfilamentation (hyphae and pseudohyphae) under both inducing and noninducing conditions C. albicans orf19.6124 ORF ACE2 CAL0005982 PMID: 16998073|CGD_REF: CAL0117037 homozygous diploid, classical genetics null SC5314 filamentous growth: decreased hypoxic conditions C. albicans orf19.6124 ORF ACE2 CAL0005982 PMID: 21375589|CGD_REF: CAL0141772 homozygous diploid, classical genetics null CAF2-1 resistance to chemicals: decreased tunicamycin C. albicans orf19.6124 ORF ACE2 CAL0005982 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: decreased growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.6124 ORF ACE2 CAL0005982 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: abnormal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.6124 ORF ACE2 CAL0005982 PMID: 22359502|CGD_REF: CAL0000144048 homozygous diploid, classical genetics null BWP17 viable insertion mutant, independent BWP17 and SN152 deletion mutants also tested C. albicans orf19.6124 ORF ACE2 CAL0005982 PMID: 22359502|CGD_REF: CAL0000144048 homozygous diploid, classical genetics null BWP17 adhesion: decreased insertion mutant, independent BWP17 and SN152 deletion mutants also tested C. albicans orf19.6124 ORF ACE2 CAL0005982 PMID: 15255906|CGD_REF: CAL0082068 homozygous diploid, classical genetics null CAI-4 biofilm formation: absent C. albicans orf19.6124 ORF ACE2 CAL0005982 PMID: 23856128|CGD_REF: CAL0000172540 homozygous diploid, classical genetics null BWP17 resistance to chemicals: decreased propolis C. albicans orf19.6124 ORF ACE2 CAL0005982 PMID: 15255906|CGD_REF: CAL0082068 homozygous diploid, classical genetics null Not recorded virulence: decreased mouse intravenous infection C. albicans orf19.6124 ORF ACE2 CAL0005982 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.6124 ORF ACE2 CAL0005982 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.6126 ORF KGD2 CAL0005983 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient YPD medium C. albicans orf19.6126 ORF KGD2 CAL0005983 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 invasive growth: decreased solid SLAD media C. albicans orf19.6127 ORF LPD1 CAL0005984 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.6127 ORF LPD1 CAL0005984 PMID: 20571955|CGD_REF: CAL0125847 heterozygous diploid, classical genetics overexpression SC5314 filamentous growth: increased subtle effect in a wild-type background, hyperfilamentation more easily observed in the kem1 null mutant C. albicans orf19.6127 ORF LPD1 CAL0005984 PMID: 20601046|CGD_REF: CAL0125887 homozygous diploid, classical genetics null lpd1::hph/lpd1::hisG CAI-4 viable C. albicans orf19.6127 ORF LPD1 CAL0005984 PMID: 20601046|CGD_REF: CAL0125887 homozygous diploid, classical genetics null lpd1::hph/lpd1::hisG CAI-4 respiratory growth: absent non-fermentable carbon sources (glycerol, ethanol, potassium acetate, and citrate) tested C. albicans orf19.6127 ORF LPD1 CAL0005984 PMID: 20601046|CGD_REF: CAL0125887 homozygous diploid, classical genetics null lpd1::hph/lpd1::hisG CAI-4 filamentous growth: absent serum-containing YEP medium C. albicans orf19.6127 ORF LPD1 CAL0005984 PMID: 20601046|CGD_REF: CAL0125887 homozygous diploid, classical genetics null lpd1::hph/lpd1::hisG CAI-4 resistance to chemicals: decreased hydrogen peroxide (0.5 mM) C. albicans orf19.6131 ORF KSR1 CAL0006004 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.6131 ORF KSR1 CAL0006004 PMID: 16431155|CGD_REF: CAL0115694 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.6131 ORF KSR1 CAL0006004 PMID: 16431155|CGD_REF: CAL0115694 homozygous diploid, classical genetics null Not recorded resistance to chemicals: normal myriocin C. albicans orf19.6131 ORF KSR1 CAL0006004 PMID: 16431155|CGD_REF: CAL0115694 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased Aureobasidin A C. albicans orf19.6135.1 ORF SMX4 CAF0007066 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.6135.1 ORF SMX4 CAF0007066 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient YPD medium C. albicans orf19.6135.1 ORF SMX4 CAF0007066 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient SC medium C. albicans orf19.6135.1 ORF SMX4 CAF0007066 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient YNB medium C. albicans orf19.6135.1 ORF SMX4 CAF0007066 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient SLAD medium C. albicans orf19.6136 ORF CAL0006009 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient SC medium C. albicans orf19.6141 ORF HGT16 CAL0006028 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.6143 ORF CAL0006030 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.6143 ORF CAL0006030 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.6143 ORF CAL0006030 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.6143 ORF CAL0006030 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.6143 ORF CAL0006030 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.6146 ORF CLG1 CAL0006031 PMID: 21414038|CGD_REF: CAL0141808 homozygous diploid, classical genetics null BWP17 viable C. albicans orf19.6148 ORF CAL0006033 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.6151 ORF ARC15 CAL0006043 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.6151 ORF ARC15 CAL0006043 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, competitive growth (haploinsufficient phenotype assay, barcode deletion set) null SC5314 resistance to chemicals: decreased cytochalasin D C. albicans orf19.6155 ORF CAL0006047 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.6163 ORF CSE4 CAL0006066 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.6163 ORF CSE4 CAL0006066 PMID: 12271118|CGD_REF: CAL0081622 heterozygous diploid, classical genetics repressible CAI-4 bud morphology: abnormal large-budded cells C. albicans orf19.6163 ORF CSE4 CAL0006066 PMID: 12271118|CGD_REF: CAL0081622 heterozygous diploid, classical genetics repressible CAI-4 cell cycle progression in M phase: arrested cells arrest in mitosis with unsegregated nuclei C. albicans orf19.6163 ORF CSE4 CAL0006066 PMID: 12271118|CGD_REF: CAL0081622 homozygous diploid, classical genetics null Not recorded inviable C. albicans orf19.6163 ORF CSE4 CAL0006066 PMID: 21571923|CGD_REF: CAL0142042 heterozygous diploid, classical genetics repressible cse4/PCK1(p)-CSE4 Other C. albicans cell cycle progression through the G2/M phase transition: arrested arrested cells at G2/M stage with either short or medium-long spindles C. albicans orf19.6165 ORF KGD1 CAL0006070 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.6167 ORF AYR1 CAL0006073 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.6169 ORF ATO1 CAL0006076 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.6169 ORF ATO1 CAL0006076 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient SC medium C. albicans orf19.6171 ORF NUP159 CAL0006091 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.6173 ORF STD1 CAL0006094 PMID: 19249212|CGD_REF: CAL0122456 homozygous diploid, classical genetics null BWP17 filamentous growth: increased Spider medium at 37 deg C C. albicans orf19.6175 ORF CAL0006097 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.6176 ORF SEC61 CAL0006099 PMID: 15341916|CGD_REF: CAL0082116 heterozygous diploid, classical genetics repressible Not recorded flocculation: increased C. albicans orf19.6176 ORF SEC61 CAL0006099 PMID: 15341916|CGD_REF: CAL0082116 heterozygous diploid, classical genetics repressible Not recorded vegetative growth: decreased rate severe decrease C. albicans orf19.6176 ORF SEC61 CAL0006099 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.6176 ORF SEC61 CAL0006099 PMID: 15341916|CGD_REF: CAL0082116 homozygous diploid, classical genetics null Not recorded inviable homozygous null mutant strain could not be recovered, suggesting that the gene is essential under the selection conditions C. albicans orf19.6178 ORF FBP1 CAL0006101 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.6178 ORF FBP1 CAL0006101 PMID: 17158734|CGD_REF: CAL0117267 homozygous diploid, classical genetics null Not recorded virulence: decreased slight decrease mouse intravenous infection C. albicans orf19.6178 ORF FBP1 CAL0006101 PMID: 12702281|CGD_REF: CAL0081287 homozygous diploid, classical genetics null CAI-4 viable C. albicans orf19.6178 ORF FBP1 CAL0006101 PMID: 12702281|CGD_REF: CAL0081287 homozygous diploid, classical genetics null CAI-4 utilization of carbon source: decreased unable to utilize non-fermentable carbon-sources C. albicans orf19.6182 ORF ZCF34 CAL0006117 PMID: 20041210|CGD_REF: CAL0124764 homozygous diploid, systematic mutation set null SN152 resistance to chemicals: decreased fluconazole strongly sensitive C. albicans orf19.6182 ORF ZCF34 CAL0006117 PMID: 17555439|CGD_REF: CAL0117968 homozygous diploid, classical genetics null Not recorded survival rate in stationary phase: decreased C. albicans orf19.6182 ORF ZCF34 CAL0006117 PMID: 15964282|CGD_REF: CAL0114274 homozygous diploid, systematic mutation set (split-marker transposon insertion strategy to disrupt both alleles) null BWP17 viable C. albicans orf19.6182 ORF ZCF34 CAL0006117 PMID: 15964282|CGD_REF: CAL0114274 homozygous diploid, systematic mutation set (split-marker transposon insertion strategy to disrupt both alleles) null BWP17 biofilm formation: normal C. albicans orf19.6182 ORF ZCF34 CAL0006117 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.6182 ORF ZCF34 CAL0006117 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: abnormal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.6182 ORF ZCF34 CAL0006117 PMID: 22359502|CGD_REF: CAL0000144048 homozygous diploid, classical genetics null BWP17 viable insertion mutant, independent BWP17 and SN152 deletion mutants also tested C. albicans orf19.6182 ORF ZCF34 CAL0006117 PMID: 22359502|CGD_REF: CAL0000144048 homozygous diploid, classical genetics null BWP17 adhesion: decreased insertion mutant, independent BWP17 and SN152 deletion mutants also tested C. albicans orf19.6182 ORF ZCF34 CAL0006117 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.6182 ORF ZCF34 CAL0006117 PMID: 20494978|CGD_REF: CAL0125636 heterozygous diploid, classical genetics null BWP17 resistance to chemicals: decreased clotrimazole (75 uM) growth in liquid culture confirmation of mutant phenotypes for heterozygous transposon insertion strains showing sensitivity in a large-scale assay C. albicans orf19.6182 ORF ZCF34 CAL0006117 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.6185 ORF CAL0006123 PMID: 14663094|CGD_REF: CAL0080633 homozygous diploid, systematic mutation set (homozygous insertion mutants generated with URA3-ARG4-URA3 (UAU1) cassette) null BWP17 viable C. albicans orf19.6187 ORF CAL0006125 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.6190 ORF SRB1 CAL0006140 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.6190 ORF SRB1 CAL0006140 PMID: 12524333|CGD_REF: CAL0080691 homozygous diploid, systematic mutation set (homozygous insertion mutants generated with URA3-ARG4-URA3 (UAU1) cassette) null BWP17 inviable homozygous null mutant strain could not be recovered, suggesting that the gene is essential under the selection conditions C. albicans orf19.6190 ORF SRB1 CAL0006140 PMID: 14507372|CGD_REF: CAL0088818 heterozygous diploid, large-scale survey (large-scale identification of essential genes by gene replacement and conditional expression (GRACE) method) repressible CAI-4 inviable one allele is deleted and the other is placed under repressible Tet promoter C. albicans orf19.6193 ORF TAF145 CAL0006146 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.6193 ORF TAF145 CAL0006146 PMID: 12524333|CGD_REF: CAL0080691 homozygous diploid, systematic mutation set (homozygous insertion mutants generated with URA3-ARG4-URA3 (UAU1) cassette) null BWP17 inviable homozygous null mutant strain could not be recovered, suggesting that the gene is essential under the selection conditions C. albicans orf19.6193 ORF TAF145 CAL0006146 PMID: 15964282|CGD_REF: CAL0114274 homozygous diploid, systematic mutation set (split-marker transposon insertion strategy to disrupt both alleles) null BWP17 inviable homozygous null mutant strain could not be recovered, suggesting that the gene is essential under the selection conditions C. albicans orf19.6194 ORF CAL0006148 PMID: 14663094|CGD_REF: CAL0080633 homozygous diploid, systematic mutation set (homozygous insertion mutants generated with URA3-ARG4-URA3 (UAU1) cassette) null BWP17 viable C. albicans orf19.6199 ORF CAL0006154 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.6200 ORF CAL0000426 PMID: 22438810|CGD_REF: CAL0000156986 homozygous diploid, classical genetics null BWP17 viable C. albicans orf19.6200 ORF CAL0000426 PMID: 22438810|CGD_REF: CAL0000156986 homozygous diploid, classical genetics null BWP17 virulence: decreased mutants have reduced capacity to damage oral epithelial cells in vitro model of infection (monolayers of oral epithelial cells) C. albicans orf19.6202 ORF RBT4 CAL0000427 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.6202 ORF RBT4 CAL0000427 PMID: 10978273|CGD_REF: CAL0081429 homozygous diploid, classical genetics null CAI-4 viable no apparent growth defects under various laboratory conditions C. albicans orf19.6202 ORF RBT4 CAL0000427 PMID: 10978273|CGD_REF: CAL0081429 heterozygous diploid, classical genetics null CAI-4 viable C. albicans orf19.6202 ORF RBT4 CAL0000427 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, competitive growth (haploinsufficient phenotype assay, barcode deletion set) null SC5314 resistance to chemicals: decreased ergosterol analogs (ECC69 and/or ECC1384) C. albicans orf19.6202 ORF RBT4 CAL0000427 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: decreased growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.6202 ORF RBT4 CAL0000427 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.6202 ORF RBT4 CAL0000427 PMID: 11737753|CGD_REF: CAL0085973 homozygous diploid, classical genetics null rbt4::FRT/rbt4::FRT SC5314 virulence: decreased significant reduction in virulence, an rbe1/bt4 double mutant strain showed a drastic reduction in virulence mice mouse intravenous infection C. albicans orf19.6202 ORF RBT4 CAL0000427 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.6202 ORF RBT4 CAL0000427 PMID: 17525181|CGD_REF: CAL0117858 homozygous diploid, classical genetics null Not recorded virulence: decreased mouse corneal infection C. albicans orf19.6202 ORF RBT4 CAL0000427 PMID: 10978273|CGD_REF: CAL0081429 heterozygous diploid, classical genetics null CAI-4 virulence: decreased mouse intravenous infection C. albicans orf19.6202 ORF RBT4 CAL0000427 PMID: 10978273|CGD_REF: CAL0081429 homozygous diploid, classical genetics null CAI-4 virulence: decreased mouse intravenous infection C. albicans orf19.6202 ORF RBT4 CAL0000427 PMID: 10978273|CGD_REF: CAL0081429 homozygous diploid, classical genetics null CAI-4 virulence: decreased rabbit corneal infection C. albicans orf19.6202 ORF RBT4 CAL0000427 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.6209 ORF CAL0000431 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.6213 ORF SUI2 CAL0000442 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.6213 ORF SUI2 CAL0000442 PMID: 21135205|CGD_REF: CAL0139967 heterozygous diploid, large-scale survey (large-scale identification of genes essential for virulence in mouse) repressible CAI-4 virulence: absent mouse intravenous infection C. albicans orf19.6214 ORF ATC1 CAL0000443 PMID: 17464051|CGD_REF: CAL0117728 homozygous diploid, classical genetics null Not recorded germ tube formation: delayed C. albicans orf19.6214 ORF ATC1 CAL0000443 PMID: 17464051|CGD_REF: CAL0117728 homozygous diploid, classical genetics null Not recorded heat sensitivity: decreased C. albicans orf19.6214 ORF ATC1 CAL0000443 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.6214 ORF ATC1 CAL0000443 PMID: 15252058|CGD_REF: CAL0082067 heterozygous diploid, classical genetics null Not recorded viable C. albicans orf19.6214 ORF ATC1 CAL0000443 PMID: 15252058|CGD_REF: CAL0082067 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.6214 ORF ATC1 CAL0000443 PMID: 17464051|CGD_REF: CAL0117728 homozygous diploid, classical genetics null Not recorded oxidative stress resistance: increased hydrogen peroxide C. albicans orf19.6214 ORF ATC1 CAL0000443 PMID: 17464051|CGD_REF: CAL0117728 homozygous diploid, classical genetics null Not recorded ionic stress resistance: increased sodium chloride C. albicans orf19.6214 ORF ATC1 CAL0000443 PMID: 15252058|CGD_REF: CAL0082067 homozygous diploid, classical genetics null Not recorded utilization of carbon source: absent trehalose C. albicans orf19.6214 ORF ATC1 CAL0000443 PMID: 17464051|CGD_REF: CAL0117728 homozygous diploid, classical genetics null Not recorded virulence: decreased mouse intravenous infection C. albicans orf19.6217 ORF PGA63 CAL0000444 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.6219 ORF CAL0000445 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.6219 ORF CAL0000445 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.6219 ORF CAL0000445 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: decreased rate liquid synthetic complete medium C. albicans orf19.6219 ORF CAL0000445 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.6220.4 ORF CAF0007069 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient YPD medium C. albicans orf19.6220.4 ORF CAF0007069 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient SLAD medium C. albicans orf19.6220.4 ORF CAF0007069 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 invasive growth: decreased solid SLAD media C. albicans orf19.6222 ORF SPO22 CAL0000457 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient SC medium C. albicans orf19.6222 ORF SPO22 CAL0000457 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient SLAD medium C. albicans orf19.6224 ORF CAL0000459 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.6225 ORF PCL7 CAL0000460 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.6225 ORF PCL7 CAL0000460 PMID: 21135205|CGD_REF: CAL0139967 heterozygous diploid, competitive growth (large-scale identification of genes essential for virulence in mouse) repressible CAI-4 virulence: normal mouse intravenous infection C. albicans orf19.6227 ORF CAL0000461 PMID: 22581526|CGD_REF: CAL0000157314 homozygous diploid, systematic mutation set null BWP17 resistance to chemicals: decreased amphotericin B C. albicans orf19.6229 ORF CAT1 CAL0000462 PMID: 12906099|CGD_REF: CAL0080838 homozygous diploid, classical genetics null Not recorded vegetative growth: decreased rate 42 deg C C. albicans orf19.6229 ORF CAT1 CAL0000462 PMID: 12906099|CGD_REF: CAL0080838 heterozygous diploid, classical genetics null Not recorded viable C. albicans orf19.6229 ORF CAT1 CAL0000462 PMID: 12906099|CGD_REF: CAL0080838 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.6229 ORF CAT1 CAL0000462 PMID: 18791036|CGD_REF: CAL0120270 heterozygous diploid, classical genetics null Not recorded viable C. albicans orf19.6229 ORF CAT1 CAL0000462 PMID: 18791036|CGD_REF: CAL0120270 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.6229 ORF CAT1 CAL0000462 PMID: 9573075|CGD_REF: CAL0080820 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.6229 ORF CAT1 CAL0000462 PMID: 12906099|CGD_REF: CAL0080838 homozygous diploid, classical genetics null Not recorded protein activity: absent catalase activity is not induced in response to H2O2 catalase C. albicans orf19.6229 ORF CAT1 CAL0000462 PMID: 12906099|CGD_REF: CAL0080838 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased sodium dodecyl sulfate C. albicans orf19.6229 ORF CAT1 CAL0000462 PMID: 18791036|CGD_REF: CAL0120270 homozygous diploid, classical genetics null SC5314 hyphal growth: abnormal increased induction of hyphal growth in response to H2O2 C. albicans orf19.6229 ORF CAT1 CAL0000462 PMID: 18791036|CGD_REF: CAL0120270 heterozygous diploid, classical genetics null SC5314 hyphal growth: abnormal reintegrant exhibits phenotype intermediate between homozygous null and wild type with respect to H2O2 induction of hyphal growth C. albicans orf19.6229 ORF CAT1 CAL0000462 PMID: 18352908|CGD_REF: CAL0118918 homozygous diploid, classical genetics null CAI-4 hyphal growth: absent Spider medium and corn meal medium C. albicans orf19.6229 ORF CAT1 CAL0000462 PMID: 18791036|CGD_REF: CAL0120270 homozygous diploid, classical genetics null Not recorded hyphal growth: abnormal hydrogen peroxide increased induction of hyphal growth in response to H2O2 C. albicans orf19.6229 ORF CAT1 CAL0000462 PMID: 12906099|CGD_REF: CAL0080838 heterozygous diploid, classical genetics null Not recorded oxidative stress resistance: decreased hydrogen peroxide sensitivity is intermediate between that of the homozygous null mutant and wild type C. albicans orf19.6229 ORF CAT1 CAL0000462 PMID: 12906099|CGD_REF: CAL0080838 homozygous diploid, classical genetics null Not recorded oxidative stress resistance: decreased hydrogen peroxide C. albicans orf19.6229 ORF CAT1 CAL0000462 PMID: 9573075|CGD_REF: CAL0080820 homozygous diploid, classical genetics null Not recorded oxidative stress resistance: decreased hydrogen peroxide C. albicans orf19.6229 ORF CAT1 CAL0000462 PMID: 12906099|CGD_REF: CAL0080838 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased NP40 C. albicans orf19.6229 ORF CAT1 CAL0000462 PMID: 12906099|CGD_REF: CAL0080838 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased Triton X-100 C. albicans orf19.6229 ORF CAT1 CAL0000462 PMID: 12906099|CGD_REF: CAL0080838 homozygous diploid, classical genetics null Not recorded virulence: decreased exhibits decreased liver colonization mouse intravenous infection C. albicans orf19.6229 ORF CAT1 CAL0000462 PMID: 12906099|CGD_REF: CAL0080838 heterozygous diploid, classical genetics null Not recorded virulence: decreased liver colonization is intermediate between that of the homozygous null mutant and wild type mouse intravenous infection C. albicans orf19.6229 ORF CAT1 CAL0000462 PMID: 9573075|CGD_REF: CAL0080820 homozygous diploid, classical genetics null Not recorded virulence: decreased mouse intravenous infection C. albicans orf19.6230 ORF CAL0000473 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.6232 ORF NPR1 CAL0000475 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.6232 ORF NPR1 CAL0000475 PMID: 21278231|CGD_REF: CAL0141432 homozygous diploid, classical genetics null SC5314 utilization of nitrogen source: decreased ammonium C. albicans orf19.6232 ORF NPR1 CAL0000475 PMID: 21278231|CGD_REF: CAL0141432 homozygous diploid, classical genetics null SC5314 nutrient uptake: decreased ammonium C. albicans orf19.6232 ORF NPR1 CAL0000475 PMID: 21278231|CGD_REF: CAL0141432 homozygous diploid, classical genetics null SC5314 utilization of nitrogen source: decreased threonine C. albicans orf19.6232 ORF NPR1 CAL0000475 PMID: 21278231|CGD_REF: CAL0141432 homozygous diploid, classical genetics null SC5314 utilization of nitrogen source: decreased phenylalanine C. albicans orf19.6232 ORF NPR1 CAL0000475 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.6232 ORF NPR1 CAL0000475 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.6232 ORF NPR1 CAL0000475 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.6232 ORF NPR1 CAL0000475 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.6233 ORF CAL0000476 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.6234 ORF CAL0000477 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, competitive growth (haploinsufficient phenotype assay, barcode deletion set) null SC5314 resistance to chemicals: decreased 5-fluorouracil C. albicans orf19.6234 ORF CAL0000477 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, competitive growth (haploinsufficient phenotype assay, barcode deletion set) null SC5314 resistance to chemicals: decreased tubercidin C. albicans orf19.6234 ORF CAL0000477 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, competitive growth (haploinsufficient phenotype assay, barcode deletion set) null SC5314 resistance to chemicals: decreased flucytosine C. albicans orf19.6234 ORF CAL0000477 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.6237 ORF RAC1 CAL0000480 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.6237 ORF RAC1 CAL0000480 PMID: 16467473|CGD_REF: CAL0115508 heterozygous diploid, classical genetics null Not recorded viable C. albicans orf19.6237 ORF RAC1 CAL0000480 PMID: 16467473|CGD_REF: CAL0115508 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.6237 ORF RAC1 CAL0000480 PMID: 16467473|CGD_REF: CAL0115508 heterozygous diploid, classical genetics overexpression Not recorded viable C. albicans orf19.6237 ORF RAC1 CAL0000480 PMID: 16467473|CGD_REF: CAL0115508 homozygous diploid, classical genetics null Not recorded actin cytoskeleton morphology: normal C. albicans orf19.6237 ORF RAC1 CAL0000480 PMID: 16467473|CGD_REF: CAL0115508 homozygous diploid, classical genetics null BWP17 hyphal growth: normal liquid media or serum-containing solid media C. albicans orf19.6237 ORF RAC1 CAL0000480 PMID: 16467473|CGD_REF: CAL0115508 homozygous diploid, classical genetics overexpression BWP17 hyphal growth: normal serum-containing medium C. albicans orf19.6237 ORF RAC1 CAL0000480 PMID: 16467473|CGD_REF: CAL0115508 homozygous diploid, classical genetics null BWP17 invasive growth: absent embedded in agar C. albicans orf19.6237 ORF RAC1 CAL0000480 PMID: 16467473|CGD_REF: CAL0115508 heterozygous diploid, classical genetics overexpression Not recorded cell size: abnormal cell size is heterogeneous C. albicans orf19.6237 ORF RAC1 CAL0000480 PMID: 16467473|CGD_REF: CAL0115508 heterozygous diploid, classical genetics null BWP17 filamentous growth: normal reintegrant C. albicans orf19.6237 ORF RAC1 CAL0000480 PMID: 16467473|CGD_REF: CAL0115508 homozygous diploid, classical genetics null BWP17 filamentous growth: normal serum-containing, GlcNAc-containing, or Spider media C. albicans orf19.6237 ORF RAC1 CAL0000480 PMID: 20444104|CGD_REF: CAL0125731 homozygous diploid, classical genetics null BWP17 resistance to chemicals: decreased Calcofluor White C. albicans orf19.6237 ORF RAC1 CAL0000480 PMID: 20444104|CGD_REF: CAL0125731 homozygous diploid, classical genetics null BWP17 resistance to chemicals: decreased Congo Red C. albicans orf19.6238 ORF CAL0000481 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.6238 ORF CAL0000481 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.6238 ORF CAL0000481 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.6238 ORF CAL0000481 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.6238 ORF CAL0000481 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.6239 ORF CAL0000482 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.6239 ORF CAL0000482 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 invasive growth: decreased solid SLAD media C. albicans orf19.6242 ORF CYK3 CAL0000494 PMID: 20383711|CGD_REF: CAL0125351 homozygous diploid, classical genetics null SC5314 inviable C. albicans orf19.6242 ORF CYK3 CAL0000494 PMID: 20383711|CGD_REF: CAL0125351 homozygous diploid, classical genetics repressible pMET3::CYK3 SC5314 cell shape: abnormal methionine and cysteine in the medium (repressing conditions) elongated and misshapen cells C. albicans orf19.6242 ORF CYK3 CAL0000494 PMID: 20383711|CGD_REF: CAL0125351 homozygous diploid, classical genetics repressible pMET3::CYK3 SC5314 chitin deposition: abnormal methionine and cysteine in the medium (repressing conditions) C. albicans orf19.6242 ORF CYK3 CAL0000494 PMID: 20383711|CGD_REF: CAL0125351 homozygous diploid, classical genetics repressible pMET3::CYK3 SC5314 cytokinesis: arrested methionine and cysteine in the medium (repressing conditions) C. albicans orf19.6243 ORF VPS34 CAL0000495 PMID: 15870472|CGD_REF: CAL0082691 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased cobalt(2+) C. albicans orf19.6243 ORF VPS34 CAL0000495 PMID: 17600079|CGD_REF: CAL0118017 homozygous diploid, classical genetics null Not recorded metal resistance: decreased silver(1+) C. albicans orf19.6243 ORF VPS34 CAL0000495 PMID: 15870472|CGD_REF: CAL0082691 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased nickel(2+) C. albicans orf19.6243 ORF VPS34 CAL0000495 PMID: 11223944|CGD_REF: CAL0082029 homozygous diploid, classical genetics null Not recorded septum formation: abnormal septa form prematurely C. albicans orf19.6243 ORF VPS34 CAL0000495 PMID: 11065354|CGD_REF: CAL0082028 homozygous diploid, classical genetics null Not recorded heat sensitivity: increased C. albicans orf19.6243 ORF VPS34 CAL0000495 PMID: 11065354|CGD_REF: CAL0082028 homozygous diploid, classical genetics null Not recorded vacuolar morphology: abnormal vacuoles are enlarged C. albicans orf19.6243 ORF VPS34 CAL0000495 PMID: 11223944|CGD_REF: CAL0082029 homozygous diploid, classical genetics null Not recorded vacuolar morphology: abnormal vacuoles are enlarged and electron-transparent C. albicans orf19.6243 ORF VPS34 CAL0000495 PMID: 11065354|CGD_REF: CAL0082028 homozygous diploid, classical genetics null Not recorded vegetative growth: decreased rate C. albicans orf19.6243 ORF VPS34 CAL0000495 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.6243 ORF VPS34 CAL0000495 PMID: 11065354|CGD_REF: CAL0082028 heterozygous diploid, classical genetics null Not recorded viable wild-type growth C. albicans orf19.6243 ORF VPS34 CAL0000495 PMID: 11065354|CGD_REF: CAL0082028 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.6243 ORF VPS34 CAL0000495 PMID: 11223944|CGD_REF: CAL0082029 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.6243 ORF VPS34 CAL0000495 PMID: 11223944|CGD_REF: CAL0082029 homozygous diploid, classical genetics null Not recorded protein activity: decreased carboxypeptidase Y C. albicans orf19.6243 ORF VPS34 CAL0000495 PMID: 11065354|CGD_REF: CAL0082028 homozygous diploid, classical genetics null Not recorded adhesion: decreased adhesion to mouse fibroblasts C. albicans orf19.6243 ORF VPS34 CAL0000495 PMID: 15632428|CGD_REF: CAL0103879 heterozygous diploid, classical genetics reduction of function SC5314 hyphal growth: abnormal various media homozygous VPS34TOR allele; delayed or abolished hyphal growth C. albicans orf19.6243 ORF VPS34 CAL0000495 PMID: 11065354|CGD_REF: CAL0082028 homozygous diploid, classical genetics null Not recorded hyphal growth: decreased liquid serum-containing medium, liquid Spider medium at 37 deg C C. albicans orf19.6243 ORF VPS34 CAL0000495 PMID: 11065354|CGD_REF: CAL0082028 homozygous diploid, classical genetics null Not recorded hyphal growth: delayed liquid serum-containing medium, liquid Spider medium at 37 deg C C. albicans orf19.6243 ORF VPS34 CAL0000495 PMID: 11065354|CGD_REF: CAL0082028 homozygous diploid, classical genetics null Not recorded hyphal growth: absent solid Spider plus mannitol at 37 deg C, or solid YPD plus serum C. albicans orf19.6243 ORF VPS34 CAL0000495 PMID: 11065354|CGD_REF: CAL0082028 heterozygous diploid, classical genetics null Not recorded hyphal growth: normal C. albicans orf19.6243 ORF VPS34 CAL0000495 PMID: 15632428|CGD_REF: CAL0103879 homozygous diploid, classical genetics reduction of function VPS34TOR/VPS34TOR Not recorded adhesion: decreased adhesion to endothelial cells C. albicans orf19.6243 ORF VPS34 CAL0000495 PMID: 15632428|CGD_REF: CAL0103879 homozygous diploid, classical genetics reduction of function VPS34TOR/VPS34TOR Not recorded endocytosis: abnormal prevacuole to vacuole transport is blocked C. albicans orf19.6243 ORF VPS34 CAL0000495 PMID: 15632428|CGD_REF: CAL0103879 homozygous diploid, classical genetics reduction of function VPS34TOR/VPS34TOR Not recorded virulence: absent kidney colonization is reduced mouse intravenous infection C. albicans orf19.6243 ORF VPS34 CAL0000495 PMID: 11065354|CGD_REF: CAL0082028 heterozygous diploid, classical genetics null Not recorded cellular morphology: normal C. albicans orf19.6243 ORF VPS34 CAL0000495 PMID: 11223944|CGD_REF: CAL0082029 homozygous diploid, classical genetics null Not recorded nuclear position: abnormal defective nuclear migration and segregation C. albicans orf19.6243 ORF VPS34 CAL0000495 PMID: 11065354|CGD_REF: CAL0082028 homozygous diploid, classical genetics null Not recorded osmotic stress resistance: decreased C. albicans orf19.6243 ORF VPS34 CAL0000495 PMID: 11223944|CGD_REF: CAL0082029 homozygous diploid, classical genetics null Not recorded endocytosis: decreased prevacuole to vacuole transport is blocked C. albicans orf19.6243 ORF VPS34 CAL0000495 PMID: 15870472|CGD_REF: CAL0082691 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased manganese(2+) C. albicans orf19.6243 ORF VPS34 CAL0000495 PMID: 15870472|CGD_REF: CAL0082691 homozygous diploid, classical genetics null Not recorded metal resistance: decreased copper(2+) C. albicans orf19.6243 ORF VPS34 CAL0000495 PMID: 17600079|CGD_REF: CAL0118017 homozygous diploid, classical genetics null Not recorded metal resistance: decreased copper(2+) C. albicans orf19.6243 ORF VPS34 CAL0000495 PMID: 15870472|CGD_REF: CAL0082691 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased zinc(2+) C. albicans orf19.6243 ORF VPS34 CAL0000495 PMID: 23856128|CGD_REF: CAL0000172540 homozygous diploid, classical genetics null BWP17 resistance to chemicals: decreased propolis C. albicans orf19.6243 ORF VPS34 CAL0000495 PMID: 11065354|CGD_REF: CAL0082028 homozygous diploid, classical genetics null Not recorded virulence: decreased no kidney colonization observed mouse intravenous infection C. albicans orf19.6243 ORF VPS34 CAL0000495 PMID: 11065354|CGD_REF: CAL0082028 homozygous diploid, classical genetics null Not recorded virulence: absent mouse intravenous infection C. albicans orf19.6243 ORF VPS34 CAL0000495 PMID: 11065354|CGD_REF: CAL0082028 heterozygous diploid, classical genetics null Not recorded virulence: normal mouse intravenous infection C. albicans orf19.6243 ORF VPS34 CAL0000495 PMID: 20140194|CGD_REF: CAL0124995 homozygous diploid, classical genetics null Other C. albicans resistance to chemicals: decreased caspofungin C. albicans orf19.6243 ORF VPS34 CAL0000495 PMID: 20140194|CGD_REF: CAL0124995 homozygous diploid, classical genetics null Other C. albicans protein/peptide distribution: abnormal mother-daughter cell bud-neck localization not observed in mutants Sep7-GFP C. albicans orf19.6243 ORF VPS34 CAL0000495 PMID: 20140194|CGD_REF: CAL0124995 homozygous diploid, classical genetics null Other C. albicans viable caspofungin C. albicans orf19.6243 ORF VPS34 CAL0000495 PMID: 20140194|CGD_REF: CAL0124995 homozygous diploid, classical genetics null Other C. albicans viable C. albicans orf19.6243 ORF VPS34 CAL0000495 PMID: 20140194|CGD_REF: CAL0124995 homozygous diploid, classical genetics null Other C. albicans oxidative stress resistance: decreased hydrogen peroxide C. albicans orf19.6245 ORF CAL0000497 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.6245 ORF CAL0000497 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.6245 ORF CAL0000497 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.6245 ORF CAL0000497 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.6246 ORF CAL0000498 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.6247 ORF CAL0000499 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient SC medium C. albicans orf19.6247 ORF CAL0000499 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient YNB medium C. albicans orf19.6247 ORF CAL0000499 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient SLAD medium C. albicans orf19.6249 ORF HAK1 CAL0000501 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: decreased growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.6249 ORF HAK1 CAL0000501 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.6249 ORF HAK1 CAL0000501 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.6249 ORF HAK1 CAL0000501 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.6249 ORF HAK1 CAL0000501 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 invasive growth: decreased solid SLAD media C. albicans orf19.6252 ORF CAL0000512 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.6252 ORF CAL0000512 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 invasive growth: decreased solid SLAD media C. albicans orf19.6253 ORF RPS23A CAL0000513 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.6254 ORF ANT1 CAL0000514 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.6259 ORF CAL0000517 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.6261 ORF BPH1 CAL0000533 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.6261 ORF BPH1 CAL0000533 PMID: 14663094|CGD_REF: CAL0080633 homozygous diploid, systematic mutation set (homozygous insertion mutants generated with URA3-ARG4-URA3 (UAU1) cassette) null BWP17 viable C. albicans orf19.6263 ORF CAL0000536 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.6265 ORF RPS22A CAL0000540 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.6265.1 ORF RPS14B CAF0007074 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient YPD medium C. albicans orf19.6267 ORF CAL0000543 PMID: 14663094|CGD_REF: CAL0080633 homozygous diploid, systematic mutation set (homozygous insertion mutants generated with URA3-ARG4-URA3 (UAU1) cassette) null BWP17 viable C. albicans orf19.6267 ORF CAL0000543 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 invasive growth: decreased solid SLAD media C. albicans orf19.6268 ORF CAL0000544 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.6268 ORF CAL0000544 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 invasive growth: decreased solid SLAD media C. albicans orf19.6271 ORF CAL0000561 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.6274 ORF PBR1 CAL0000567 PMID: 19798425|CGD_REF: CAL0124304 homozygous diploid, classical genetics null Not recorded adhesion: abnormal C. albicans orf19.6274 ORF PBR1 CAL0000567 PMID: 19798425|CGD_REF: CAL0124304 homozygous diploid, classical genetics null Other C. albicans biofilm formation: abnormal C. albicans orf19.6275 ORF CAL0000569 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient YPD medium C. albicans orf19.6283 ORF CAL0000591 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.6284 ORF CAL0000593 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.6285 ORF GLC7 CAL0000595 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.6285 ORF GLC7 CAL0000595 PMID: 18708562|CGD_REF: CAL0119375 heterozygous diploid, classical genetics null Not recorded viable C. albicans orf19.6285 ORF GLC7 CAL0000595 PMID: 22542681|CGD_REF: CAL0000157242 heterozygous diploid, classical genetics repressible glc7/pMET3-GLC7 BWP17 inviable repressing conditions, on media containing methionine and cysteine C. albicans orf19.6285 ORF GLC7 CAL0000595 PMID: 22542681|CGD_REF: CAL0000157242 heterozygous diploid, classical genetics repressible glc7/pMET3-GLC7 BWP17 cell cycle progression through the G2/M phase transition: arrested repressing conditions, on media containing methionine and cysteine C. albicans orf19.6285 ORF GLC7 CAL0000595 PMID: 22542681|CGD_REF: CAL0000157242 heterozygous diploid, classical genetics null glc7::ARG4/GLC7 BWP17 resistance to chemicals: decreased methyl methanesulfonate C. albicans orf19.6285 ORF GLC7 CAL0000595 PMID: 22542681|CGD_REF: CAL0000157242 heterozygous diploid, classical genetics null glc7::ARG4/GLC7 BWP17 resistance to chemicals: decreased hydroxyurea C. albicans orf19.6285 ORF GLC7 CAL0000595 PMID: 22542681|CGD_REF: CAL0000157242 heterozygous diploid, classical genetics null glc7::ARG4/GLC7 BWP17 resistance to chemicals: decreased 4-nitroquinoline N-oxide C. albicans orf19.6285 ORF GLC7 CAL0000595 PMID: 22542681|CGD_REF: CAL0000157242 heterozygous diploid, classical genetics null glc7::ARG4/GLC7 BWP17 UV resistance: decreased C. albicans orf19.6286 ORF CAL0000597 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 invasive growth: decreased solid SLAD media C. albicans orf19.6287 ORF AAT21 CAL0000598 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.6291 ORF CAL0000615 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 invasive growth: decreased solid SLAD media C. albicans orf19.6293 ORF EMP24 CAL0000619 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: decreased growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.6293 ORF EMP24 CAL0000619 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: abnormal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.6293 ORF EMP24 CAL0000619 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.6293 ORF EMP24 CAL0000619 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.6294 ORF MYO1 CAL0000620 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.6295 ORF MAS2 CAL0000621 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient YPD medium C. albicans orf19.6295 ORF MAS2 CAL0000621 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient SC medium C. albicans orf19.6296 ORF VPS22 CAL0000623 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.6296 ORF VPS22 CAL0000623 PMID: 22427429|CGD_REF: CAL0000156990 homozygous diploid, classical genetics null BWP17 protein/peptide modification: absent mutants don't process RIM8-HA RIM8-HA C. albicans orf19.6296 ORF VPS22 CAL0000623 PMID: 22427429|CGD_REF: CAL0000156990 homozygous diploid, classical genetics null BWP17 protein/peptide modification: absent Rim8-HA was not modified to the 95-105 kD forms in this mutant at pH 8 Rim8-HA C. albicans orf19.6296 ORF VPS22 CAL0000623 PMID: 22427429|CGD_REF: CAL0000156990 homozygous diploid, classical genetics null vps22::ARG4/vps22::URA3- dpl200 RIM8-HA::HIS1/RIM8 BWP17 protein/peptide modification: absent Rim8-HA was not modified to the 95-105 kD forms in this mutant at pH 8 Rim8-HA C. albicans orf19.6296 ORF VPS22 CAL0000623 PMID: 22427429|CGD_REF: CAL0000156990 homozygous diploid, classical genetics null BWP17 protein/peptide modification: absent Rim8-HA was not modified to the 95-105 kD forms in this mutant at pH 8 Rim8-HA C. albicans orf19.6296 ORF VPS22 CAL0000623 PMID: 22427429|CGD_REF: CAL0000156990 homozygous diploid, classical genetics null BWP17 protein/peptide modification: abnormal defective for RIM8-HA-processing RIM8-HA C. albicans orf19.6296 ORF VPS22 CAL0000623 PMID: 20581294|CGD_REF: CAL0125802 homozygous diploid, classical genetics null BWP17 alkaline pH resistance: decreased YPD pH 9, 2 days at 37 degrees C C. albicans orf19.6296 ORF VPS22 CAL0000623 PMID: 20581294|CGD_REF: CAL0125802 homozygous diploid, classical genetics null BWP17 viable C. albicans orf19.6296 ORF VPS22 CAL0000623 PMID: 20581294|CGD_REF: CAL0125802 homozygous diploid, classical genetics null BWP17 hyphal growth: absent M199 pH 8 plates, 37 degrees C, 6 days no peripheral hyphae produced C. albicans orf19.6296 ORF VPS22 CAL0000623 PMID: 20581294|CGD_REF: CAL0125802 homozygous diploid, classical genetics null BWP17 metal resistance: decreased lithium chloride (150 mM) YPD plus 150 mM lithium chloride C. albicans orf19.6296 ORF VPS22 CAL0000623 PMID: 20581294|CGD_REF: CAL0125802 homozygous diploid, classical genetics null BWP17 resistance to chemicals: decreased iron chelators YPD plus 150 micromolar bathophenanthrolinedisulfonic acid (BPS) C. albicans orf19.6297 ORF CAL0000624 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.6302 ORF PGA39 CAL0001233 PMID: 18765290|CGD_REF: CAL0119430 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.6302 ORF PGA39 CAL0001233 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 invasive growth: decreased solid SLAD media C. albicans orf19.6305 ORF CAL0001235 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.6305 ORF CAL0001235 PMID: 19289605|CGD_REF: CAL0122500 homozygous diploid, classical genetics null Not recorded utilization of carbon source: absent acetic acid C. albicans orf19.6305 ORF CAL0001235 PMID: 19289605|CGD_REF: CAL0122500 homozygous diploid, classical genetics null Not recorded utilization of carbon source: absent ethanol C. albicans orf19.6305 ORF CAL0001235 PMID: 19289605|CGD_REF: CAL0122500 homozygous diploid, classical genetics null Not recorded utilization of carbon source: decreased fatty acid C. albicans orf19.6306 ORF CAL0001236 PMID: 19289605|CGD_REF: CAL0122500 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.6306 ORF CAL0001236 PMID: 19289605|CGD_REF: CAL0122500 homozygous diploid, classical genetics null Not recorded utilization of carbon source: absent acetic acid C. albicans orf19.6306 ORF CAL0001236 PMID: 19289605|CGD_REF: CAL0122500 homozygous diploid, classical genetics null Not recorded utilization of carbon source: absent oleic acid C. albicans orf19.6306 ORF CAL0001236 PMID: 19289605|CGD_REF: CAL0122500 homozygous diploid, classical genetics null Not recorded utilization of carbon source: absent ethanol C. albicans orf19.6309 ORF MSS11 CAL0001239 PMID: 19734367|CGD_REF: CAL0124168 homozygous diploid, classical genetics null CAI-4 hyphal growth: decreased liquid serum-containing medium fewer and shorter hyphae C. albicans orf19.6309 ORF MSS11 CAL0001239 PMID: 19734367|CGD_REF: CAL0124168 homozygous diploid, classical genetics null CAI-4 filamentous growth: absent Lee's medium C. albicans orf19.6309 ORF MSS11 CAL0001239 PMID: 19734367|CGD_REF: CAL0124168 heterozygous diploid, classical genetics overexpression CAI-4 filamentous growth: increased C. albicans orf19.6309 ORF MSS11 CAL0001239 PMID: 24752399|CGD_REF: CAL0000173845 homozygous diploid, classical genetics null SC5314 biofilm formation: decreased C. albicans orf19.6309 ORF MSS11 CAL0001239 PMID: 24752399|CGD_REF: CAL0000173845 homozygous diploid, classical genetics null SC5314 virulence: decreased mouse intravenous infection C. albicans orf19.6312 ORF RPS3 CAL0001259 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.6313 ORF MNT4 CAL0001260 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.6313 ORF MNT4 CAL0001260 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.6313 ORF MNT4 CAL0001260 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.6313 ORF MNT4 CAL0001260 PMID: 23886038|CGD_REF: CAL0000172548 homozygous diploid, classical genetics null CAI-4 viable C. albicans orf19.6313 ORF MNT4 CAL0001260 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.6313.2 ORF MVB12 CAF0007076 PMID: 20581294|CGD_REF: CAL0125802 homozygous diploid, classical genetics null BWP17 filamentous growth: abnormal shortened peripheral filaments around colony edge C. albicans orf19.6313.2 ORF MVB12 CAF0007076 PMID: 20581294|CGD_REF: CAL0125802 homozygous diploid, classical genetics null BWP17 viable C. albicans orf19.6313.2 ORF MVB12 CAF0007076 PMID: 20581294|CGD_REF: CAL0125802 homozygous diploid, classical genetics null BWP17 protein/peptide modification: absent Rim101p C. albicans orf19.6313.2 ORF MVB12 CAF0007076 PMID: 20581294|CGD_REF: CAL0125802 homozygous diploid, classical genetics null BWP17 metal resistance: decreased lithium chloride (150 mM) YPD plus 150 mM lithium chloride C. albicans orf19.6314 ORF RPB8 CAL0001261 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.6314 ORF RPB8 CAL0001261 PMID: 19623926|CGD_REF: CAL0124054 heterozygous diploid, competitive growth (haploinsufficient phenotype assay, barcode deletion set) null SC5314 resistance to chemicals: increased parnafungin C. albicans orf19.6314 ORF RPB8 CAL0001261 PMID: 21135205|CGD_REF: CAL0139967 heterozygous diploid, competitive growth (large-scale identification of genes essential for virulence in mouse) repressible CAI-4 virulence: decreased mouse intravenous infection C. albicans orf19.6316 ORF CAL0001263 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.6316 ORF CAL0001263 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 invasive growth: decreased solid SLAD media C. albicans orf19.6317 ORF ADE6 CAL0001264 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.6317 ORF ADE6 CAL0001264 PMID: 21135205|CGD_REF: CAL0139967 heterozygous diploid, competitive growth (large-scale identification of genes essential for virulence in mouse) repressible CAI-4 virulence: decreased mouse intravenous infection C. albicans orf19.6318 ORF CAL0001265 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.6318 ORF CAL0001265 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.6318 ORF CAL0001265 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.6318 ORF CAL0001265 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.6322 ORF ARD CAL0001287 PMID: 7768790|CGD_REF: CAL0080767 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.6322 ORF ARD CAL0001287 PMID: 7768790|CGD_REF: CAL0080767 homozygous diploid, classical genetics null Not recorded utilization of carbon source: absent D-arabinose C. albicans orf19.6322 ORF ARD CAL0001287 PMID: 7768790|CGD_REF: CAL0080767 homozygous diploid, classical genetics null Not recorded utilization of carbon source: absent D-arabinitol C. albicans orf19.6323 ORF HPA2 CAL0001288 PMID: 19555456|CGD_REF: CAL0123821 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.6323 ORF HPA2 CAL0001288 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 invasive growth: decreased solid SLAD media C. albicans orf19.6324 ORF VID27 CAL0001289 PMID: 12773383|CGD_REF: CAL0087974 heterozygous diploid, classical genetics (haploinsufficient phenotype assay) null CAI-4 viable heterozygous transposon insertion C. albicans orf19.6324 ORF VID27 CAL0001289 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.6324 ORF VID27 CAL0001289 PMID: 12773383|CGD_REF: CAL0087974 heterozygous diploid, classical genetics (haploinsufficient phenotype assay) null CAI-4 filamentous growth: increased solid Spider medium or solid YEPD plus serum heterozygous transposon insertion C. albicans orf19.6324 ORF VID27 CAL0001289 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, competitive growth (haploinsufficient phenotype assay, barcode deletion set) null SC5314 resistance to chemicals: decreased ergosterol analogs (ECC69 and/or ECC1384) C. albicans orf19.6324 ORF VID27 CAL0001289 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.6324 ORF VID27 CAL0001289 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.6324 ORF VID27 CAL0001289 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.6327 ORF HET1 CAL0001291 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.6327 ORF HET1 CAL0001291 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: decreased growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.6327 ORF HET1 CAL0001291 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.6327 ORF HET1 CAL0001291 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.6327 ORF HET1 CAL0001291 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, classical genetics null SN152 virulence: decreased BALB/c mice mouse intravenous infection C. albicans orf19.6327 ORF HET1 CAL0001291 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.6328 ORF CAL0001292 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.633 ORF CRG1 CAL0000972 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.633 ORF CRG1 CAL0000972 PMID: 24083538|CGD_REF: CAL0000172998 haploid, classical genetics null SN87 resistance to chemicals: decreased cantharidin C. albicans orf19.633 ORF CRG1 CAL0000972 PMID: 24083538|CGD_REF: CAL0000172998 haploid, classical genetics null SN87 chemical compound accumulation: increased phytoceramide C. albicans orf19.633 ORF CRG1 CAL0000972 PMID: 24083538|CGD_REF: CAL0000172998 haploid, classical genetics null SN87 virulence: decreased insect infection C. albicans orf19.6336 ORF PGA25 CAL0001302 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.6339 ORF NRG2 CAL0001305 PMID: 12773383|CGD_REF: CAL0087974 heterozygous diploid, classical genetics (haploinsufficient phenotype assay) unspecified CAI-4 filamentous growth: increased solid Spider medium or solid YEPD plus serum transposon insertion proximal to, but not within, the ORF C. albicans orf19.6339 ORF NRG2 CAL0001305 PMID: 12773383|CGD_REF: CAL0087974 heterozygous diploid, classical genetics (haploinsufficient phenotype assay) null CAI-4 viable heterozygous deletion C. albicans orf19.6339 ORF NRG2 CAL0001305 PMID: 12773383|CGD_REF: CAL0087974 heterozygous diploid, classical genetics (haploinsufficient phenotype assay) null CAI-4 viable heterozygous transposon insertion C. albicans orf19.6339 ORF NRG2 CAL0001305 PMID: 12773383|CGD_REF: CAL0087974 heterozygous diploid, classical genetics (haploinsufficient phenotype assay) null CAI-4 filamentous growth: increased solid Spider medium heterozygous deletion C. albicans orf19.6339 ORF NRG2 CAL0001305 PMID: 12773383|CGD_REF: CAL0087974 heterozygous diploid, classical genetics (haploinsufficient phenotype assay) null CAI-4 filamentous growth: increased solid Spider medium or solid YEPD plus serum increase is allele- and medium-dependent C. albicans orf19.6340 ORF CAL0001316 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.6341 ORF CAL0001317 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.6343 ORF FEN1 CAL0001319 PMID: 24395234|CGD_REF: CAL0000173748 homozygous diploid, classical genetics null SC5314 viable C. albicans orf19.6343 ORF FEN1 CAL0001319 PMID: 24395234|CGD_REF: CAL0000173748 homozygous diploid, classical genetics null SC5314 resistance to chemicals: decreased amphotericin B C. albicans orf19.6344 ORF RBK1 CAL0001321 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.6344 ORF RBK1 CAL0001321 PMID: 14663094|CGD_REF: CAL0080633 homozygous diploid, systematic mutation set (homozygous insertion mutants generated with URA3-ARG4-URA3 (UAU1) cassette) null BWP17 viable C. albicans orf19.6344 ORF RBK1 CAL0001321 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 invasive growth: decreased solid SLAD media C. albicans orf19.6345 ORF RPG1A CAL0001323 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.6345 ORF RPG1A CAL0001323 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, competitive growth (haploinsufficient phenotype assay, barcode deletion set) null SC5314 resistance to chemicals: decreased verrucarin C. albicans orf19.6345 ORF RPG1A CAL0001323 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, competitive growth (haploinsufficient phenotype assay, barcode deletion set) null SC5314 resistance to chemicals: decreased roridin A C. albicans orf19.6346 ORF CAL0001325 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.6347 ORF CAL0001327 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.6348 ORF CAL0001329 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.6348 ORF CAL0001329 PMID: 14663094|CGD_REF: CAL0080633 homozygous diploid, systematic mutation set (homozygous insertion mutants generated with URA3-ARG4-URA3 (UAU1) cassette) null BWP17 viable C. albicans orf19.6348 ORF CAL0001329 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.6348 ORF CAL0001329 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.6348 ORF CAL0001329 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.6348 ORF CAL0001329 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient YPD medium C. albicans orf19.6348 ORF CAL0001329 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient SC medium C. albicans orf19.6348 ORF CAL0001329 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient YNB medium C. albicans orf19.6348 ORF CAL0001329 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient SLAD medium C. albicans orf19.6348 ORF CAL0001329 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.6349 ORF RVS162 CAL0001330 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.6349 ORF RVS162 CAL0001330 PMID: 19596778|CGD_REF: CAL0123901 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.6355 ORF CAL0001341 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.6355 ORF CAL0001341 PMID: 21135205|CGD_REF: CAL0139967 heterozygous diploid, competitive growth (large-scale identification of genes essential for virulence in mouse) repressible CAI-4 virulence: decreased mouse intravenous infection C. albicans orf19.6356 ORF CAL0001343 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.6358 ORF CAL0001347 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.6358 ORF CAL0001347 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.6358 ORF CAL0001347 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: abnormal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.6358 ORF CAL0001347 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.6358 ORF CAL0001347 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.6360 ORF CAL0001356 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient YPD medium C. albicans orf19.6360 ORF CAL0001356 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient SC medium C. albicans orf19.6360 ORF CAL0001356 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient SLAD medium C. albicans orf19.6362 ORF SPA2 CAL0001359 PMID: 12940995|CGD_REF: CAL0081934 homozygous diploid, classical genetics null Not recorded septum formation: abnormal septa are misplaced C. albicans orf19.6362 ORF SPA2 CAL0001359 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.6362 ORF SPA2 CAL0001359 PMID: 12940995|CGD_REF: CAL0081934 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.6362 ORF SPA2 CAL0001359 PMID: 15976451|CGD_REF: CAL0114312 homozygous diploid, classical genetics null Not recorded protein/peptide distribution: abnormal the Spitzenkorper component Mlc1p is mislocalized to the polarisome Mlc1p C. albicans orf19.6362 ORF SPA2 CAL0001359 PMID: 12940995|CGD_REF: CAL0081934 homozygous diploid, classical genetics null Not recorded actin cytoskeleton morphology: abnormal abnormal actin distribution C. albicans orf19.6362 ORF SPA2 CAL0001359 PMID: 12940995|CGD_REF: CAL0081934 homozygous diploid, classical genetics null Not recorded hyphal growth: abnormal liquid media hyphae are thicker and more curved than wild-type hyphae C. albicans orf19.6362 ORF SPA2 CAL0001359 PMID: 12940995|CGD_REF: CAL0081934 homozygous diploid, classical genetics null CAI-4 hyphal growth: decreased solid media severe decrease C. albicans orf19.6362 ORF SPA2 CAL0001359 PMID: 12940995|CGD_REF: CAL0081934 homozygous diploid, classical genetics null Not recorded bud neck morphology: abnormal bud necks are enlarged C. albicans orf19.6362 ORF SPA2 CAL0001359 PMID: 12940995|CGD_REF: CAL0081934 homozygous diploid, classical genetics null Not recorded budding pattern: abnormal bud site selection is more random than in wild type C. albicans orf19.6362 ORF SPA2 CAL0001359 PMID: 12940995|CGD_REF: CAL0081934 homozygous diploid, classical genetics null Not recorded cell cycle progression: abnormal cells are multinucleate C. albicans orf19.6362 ORF SPA2 CAL0001359 PMID: 12940995|CGD_REF: CAL0081934 homozygous diploid, classical genetics null Not recorded cell shape: abnormal cell size and shape are irregular C. albicans orf19.6362 ORF SPA2 CAL0001359 PMID: 12940995|CGD_REF: CAL0081934 homozygous diploid, classical genetics null Not recorded cytoskeleton morphology: abnormal abnormal microtubule polarity in yeast-form cells, not hyphae C. albicans orf19.6362 ORF SPA2 CAL0001359 PMID: 12940995|CGD_REF: CAL0081934 homozygous diploid, classical genetics null Not recorded virulence: absent mouse intravenous infection C. albicans orf19.6365 ORF PTP1 CAL0001363 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.6365 ORF PTP1 CAL0001363 PMID: 14663094|CGD_REF: CAL0080633 homozygous diploid, systematic mutation set (homozygous insertion mutants generated with URA3-ARG4-URA3 (UAU1) cassette) null BWP17 viable C. albicans orf19.6365 ORF PTP1 CAL0001363 PMID: 18708562|CGD_REF: CAL0119375 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.6365 ORF PTP1 CAL0001363 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.6365 ORF PTP1 CAL0001363 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: abnormal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.6365 ORF PTP1 CAL0001363 PMID: 23856128|CGD_REF: CAL0000172540 homozygous diploid, classical genetics null BWP17 resistance to chemicals: decreased propolis C. albicans orf19.6365 ORF PTP1 CAL0001363 PMID: 18708562|CGD_REF: CAL0119375 homozygous diploid, classical genetics null Not recorded virulence: normal silkworm insect infection C. albicans orf19.6365 ORF PTP1 CAL0001363 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.6365 ORF PTP1 CAL0001363 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.6367 ORF SSB1 CAL0001367 PMID: 20571955|CGD_REF: CAL0125847 heterozygous diploid, classical genetics overexpression SC5314 filamentous growth: increased YPD, Spider and Serum medium C. albicans orf19.6369 ORF RIO2 CAL0001368 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.6373 ORF DCP2 CAL0001378 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.6374 ORF CAL0001381 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient SLAD medium C. albicans orf19.6375 ORF RPS20 CAL0001384 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.6376 ORF PTC5 CAL0001386 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.6376 ORF PTC5 CAL0001386 PMID: 18708562|CGD_REF: CAL0119375 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.6376 ORF PTC5 CAL0001386 PMID: 22882651|CGD_REF: CAL0000157685 homozygous diploid, classical genetics null RM1000 resistance to chemicals: decreased terbinafine C. albicans orf19.6376 ORF PTC5 CAL0001386 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.6376 ORF PTC5 CAL0001386 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.6376 ORF PTC5 CAL0001386 PMID: 22882651|CGD_REF: CAL0000157685 homozygous diploid, classical genetics null RM1000 metal resistance: decreased cadmium(2+) C. albicans orf19.6376 ORF PTC5 CAL0001386 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.6376 ORF PTC5 CAL0001386 PMID: 18708562|CGD_REF: CAL0119375 homozygous diploid, classical genetics null Not recorded virulence: decreased insect infection C. albicans orf19.6376 ORF PTC5 CAL0001386 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.6377 ORF CAL0001387 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.638 ORF FDH1 CAL0000982 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.6382 ORF CAL0001399 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.6385 ORF ACO1 CAL0001406 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.6387 ORF HSP104 CAL0001410 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.6387 ORF HSP104 CAL0001410 PMID: 19115836|CGD_REF: CAL0122036 heterozygous diploid, competitive growth (haploinsufficient phenotype assay, barcode deletion set) null SC5314 resistance to chemicals: decreased virgineone C. albicans orf19.6387 ORF HSP104 CAL0001410 PMID: 22635920|CGD_REF: CAL0000157381 homozygous diploid, classical genetics null SC5314 thermotolerance: decreased C. albicans orf19.6387 ORF HSP104 CAL0001410 PMID: 22635920|CGD_REF: CAL0000157381 homozygous diploid, classical genetics null SC5314 viable C. albicans orf19.6387 ORF HSP104 CAL0001410 PMID: 22635920|CGD_REF: CAL0000157381 homozygous diploid, classical genetics null SC5314 biofilm formation: decreased C. albicans orf19.6387 ORF HSP104 CAL0001410 PMID: 22635920|CGD_REF: CAL0000157381 homozygous diploid, classical genetics null SC5314 virulence: decreased C. elegans infection C. albicans orf19.6387 ORF HSP104 CAL0001410 PMID: 21209325|CGD_REF: CAL0140079 heterozygous diploid, classical genetics reduction of function hsp104/HSP104-K356R (sumoylation site mutant) BWP17 heat sensitivity: increased 30-42?C heat shock C. albicans orf19.6398 ORF CAL0001434 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.6399 ORF ATS1 CAL0001436 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.640 ORF CAL0001003 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.640 ORF CAL0001003 PMID: 21135205|CGD_REF: CAL0139967 heterozygous diploid, competitive growth (large-scale identification of genes essential for virulence in mouse) repressible CAI-4 virulence: decreased mouse intravenous infection C. albicans orf19.6403 ORF CAL0002104 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 invasive growth: decreased solid SLAD media C. albicans orf19.6404 ORF GSH2 CAL0002106 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.6407 ORF CAL0002112 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.6408 ORF CAL0002114 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.641 ORF CAL0001004 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.641 ORF CAL0001004 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.641 ORF CAL0001004 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.641 ORF CAL0001004 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.641 ORF CAL0001004 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.6411 ORF CAL0002134 PMID: 12773383|CGD_REF: CAL0087974 heterozygous diploid, classical genetics (haploinsufficient phenotype assay) null CAI-4 filamentous growth: abnormal solid Spider medium or solid YEPD plus serum increased or decreased filamentous growth, depending on the allele and medium; heterozygous transposon insertions C. albicans orf19.6411 ORF CAL0002134 PMID: 12773383|CGD_REF: CAL0087974 heterozygous diploid, classical genetics (haploinsufficient phenotype assay) null CAI-4 viable heterozygous transposon insertion C. albicans orf19.6411 ORF CAL0002134 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.6411 ORF CAL0002134 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: decreased growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.6411 ORF CAL0002134 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.6411 ORF CAL0002134 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.6411 ORF CAL0002134 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.6415.1 ORF CAF0007079 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 invasive growth: decreased solid SLAD media C. albicans orf19.6417 ORF TSR1 CAL0002141 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.6417 ORF TSR1 CAL0002141 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient SC medium C. albicans orf19.6417 ORF TSR1 CAL0002141 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient YNB medium C. albicans orf19.6417 ORF TSR1 CAL0002141 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient SLAD medium C. albicans orf19.6420 ORF PGA13 CAL0002165 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.6420 ORF PGA13 CAL0002165 PMID: 19187560|CGD_REF: CAL0122338 homozygous diploid, classical genetics null SC5314 biofilm formation: abnormal forms biofilm with altered detachment properties C. albicans orf19.6420 ORF PGA13 CAL0002165 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.6420 ORF PGA13 CAL0002165 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.6420 ORF PGA13 CAL0002165 PMID: 22343036|CGD_REF: CAL0000144044 homozygous diploid, classical genetics null CAI-4 resistance to chemicals: decreased Calcofluor White C. albicans orf19.6420 ORF PGA13 CAL0002165 PMID: 22343036|CGD_REF: CAL0000144044 homozygous diploid, classical genetics null CAI-4 resistance to chemicals: decreased Congo Red C. albicans orf19.6420 ORF PGA13 CAL0002165 PMID: 22343036|CGD_REF: CAL0000144044 homozygous diploid, classical genetics null CAI-4 thermotolerance: increased increased recovery from 60 min heat shock at 55 deg C. albicans orf19.6420 ORF PGA13 CAL0002165 PMID: 22343036|CGD_REF: CAL0000144044 homozygous diploid, classical genetics null CAI-4 resistance to chemicals: increased 5-fluorocytosine C. albicans orf19.6420 ORF PGA13 CAL0002165 PMID: 22343036|CGD_REF: CAL0000144044 homozygous diploid, classical genetics null CAI-4 filamentous growth: delayed C. albicans orf19.6420 ORF PGA13 CAL0002165 PMID: 22343036|CGD_REF: CAL0000144044 homozygous diploid, classical genetics null CAI-4 flocculation: increased C. albicans orf19.6420 ORF PGA13 CAL0002165 PMID: 22343036|CGD_REF: CAL0000144044 homozygous diploid, classical genetics null CAI-4 adhesion: increased C. albicans orf19.6420 ORF PGA13 CAL0002165 PMID: 22343036|CGD_REF: CAL0000144044 homozygous diploid, classical genetics null CAI-4 virulence: decreased mouse intravenous infection C. albicans orf19.6420 ORF PGA13 CAL0002165 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.6420 ORF PGA13 CAL0002165 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.6422 ORF SSY5 CAL0002166 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.6423 ORF CAL0002167 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.6424 ORF CAL0002169 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.6425 ORF SKI2 CAL0002171 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.6432 ORF CAL0002187 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.6434 ORF PEX19 CAL0002188 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.6435 ORF CAL0002190 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient YNB medium C. albicans orf19.6435 ORF CAL0002190 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient SLAD medium C. albicans orf19.6437 ORF CDC23 CAL0002194 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.6438 ORF CAL0002196 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.644 ORF HGT9 CAL0001007 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.6440 ORF CAL0002208 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient SC medium C. albicans orf19.6440 ORF CAL0002208 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient YNB medium C. albicans orf19.6440 ORF CAL0002208 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient SLAD medium C. albicans orf19.6442 ORF PRP8 CAL0002209 PMID: 21135205|CGD_REF: CAL0139967 heterozygous diploid, large-scale survey (large-scale identification of genes essential for virulence in mouse) repressible CAI-4 virulence: absent mouse intravenous infection C. albicans orf19.6443 ORF CAL0002210 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 invasive growth: decreased solid SLAD media C. albicans orf19.6444 ORF CAL0002212 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.6445 ORF ECI1 CAL0002213 PMID: 12773383|CGD_REF: CAL0087974 heterozygous diploid, classical genetics (haploinsufficient phenotype assay) null CAI-4 viable heterozygous transposon insertion C. albicans orf19.6449 ORF CAL0002220 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.6449 ORF CAL0002220 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.6449 ORF CAL0002220 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.6449 ORF CAL0002220 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.6449 ORF CAL0002220 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.6452 ORF RBP1 CAL0002227 PMID: 11600372|CGD_REF: CAL0081772 homozygous diploid, classical genetics null Not recorded filamentous growth: normal C. albicans orf19.6452 ORF RBP1 CAL0002227 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.6452 ORF RBP1 CAL0002227 PMID: 11600372|CGD_REF: CAL0081772 heterozygous diploid, classical genetics null Not recorded viable C. albicans orf19.6452 ORF RBP1 CAL0002227 PMID: 11600372|CGD_REF: CAL0081772 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.6452 ORF RBP1 CAL0002227 PMID: 11600372|CGD_REF: CAL0081772 homozygous diploid, classical genetics null Not recorded resistance to chemicals: increased rapamycin C. albicans orf19.6455 ORF CAL0002232 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.6456 ORF CAL0002234 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 invasive growth: decreased solid SLAD media C. albicans orf19.6457 ORF CAL0002236 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient SC medium C. albicans orf19.6459 ORF DPP3 CAL0002240 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.6459 ORF DPP3 CAL0002240 PMID: 17283095|CGD_REF: CAL0117533 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.6459 ORF DPP3 CAL0002240 PMID: 17283095|CGD_REF: CAL0117533 homozygous diploid, classical genetics null Not recorded chemical compound accumulation: decreased farnesol C. albicans orf19.6459 ORF DPP3 CAL0002240 PMID: 17283095|CGD_REF: CAL0117533 homozygous diploid, classical genetics null Not recorded virulence: decreased mouse intravenous infection C. albicans orf19.6460 ORF PEX1 CAL0002247 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.6461 ORF CAL0002249 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 invasive growth: decreased solid SLAD media C. albicans orf19.6462 ORF CAL0002251 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.6463 ORF CAL0002253 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.6463 ORF CAL0002253 PMID: 16607011|CGD_REF: CAL0115846 heterozygous diploid, classical genetics null SC5314 viable C. albicans orf19.6463 ORF CAL0002253 PMID: 16607011|CGD_REF: CAL0115846 heterozygous diploid, classical genetics repressible SC5314 viable C. albicans orf19.6463 ORF CAL0002253 PMID: 12524333|CGD_REF: CAL0080691 homozygous diploid, systematic mutation set (homozygous insertion mutants generated with URA3-ARG4-URA3 (UAU1) cassette) null BWP17 inviable homozygous null mutant strain could not be recovered, suggesting that the gene is essential under the selection conditions C. albicans orf19.6463 ORF CAL0002253 PMID: 16607011|CGD_REF: CAL0115846 homozygous diploid, classical genetics null SC5314 inviable homozygous null mutant strain could not be recovered, suggesting that the gene is essential under the selection conditions C. albicans orf19.6464 ORF CAL0002255 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.6469 ORF CAL0002266 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient YPD medium C. albicans orf19.6470 ORF AHP2 CAL0002274 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 invasive growth: decreased solid SLAD media C. albicans orf19.6477 ORF CAL0002289 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.6478 ORF YCF1 CAL0002291 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.6480 ORF CAL0002300 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.6481 ORF YPS7 CAL0002302 PMID: 17416895|CGD_REF: CAL0117926 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.6481 ORF YPS7 CAL0002302 PMID: 17416895|CGD_REF: CAL0117926 homozygous diploid, classical genetics null Not recorded pheromone sensitivity: increased alpha factor C. albicans orf19.6481 ORF YPS7 CAL0002302 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.6481 ORF YPS7 CAL0002302 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.6481 ORF YPS7 CAL0002302 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.6481 ORF YPS7 CAL0002302 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.6481 ORF YPS7 CAL0002302 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 invasive growth: decreased solid SLAD media C. albicans orf19.6486 ORF LDG3 CAL0002312 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient YPD medium C. albicans orf19.6487 ORF CAL0002314 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 invasive growth: decreased solid SLAD media C. albicans orf19.6489 ORF FMP45 CAL0002318 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.6489 ORF FMP45 CAL0002318 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, competitive growth (haploinsufficient phenotype assay, barcode deletion set) null SC5314 resistance to chemicals: decreased amphotericin B C. albicans orf19.6489 ORF FMP45 CAL0002318 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, competitive growth (haploinsufficient phenotype assay, barcode deletion set) null SC5314 resistance to chemicals: decreased ergosterol analogs (ECC69 and/or ECC1384) C. albicans orf19.6489 ORF FMP45 CAL0002318 PMID: 21115741|CGD_REF: CAL0139952 homozygous diploid, classical genetics null fmp45::HIS1/fmp45::NAT BWP17 viable C. albicans orf19.649 ORF CAL0001014 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: decreased growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.649 ORF CAL0001014 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: abnormal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.649 ORF CAL0001014 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, classical genetics null SN152 germ tube formation: decreased serum-containing medium C. albicans orf19.649 ORF CAL0001014 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.649 ORF CAL0001014 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.6502 ORF CAL0003030 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.6502 ORF CAL0003030 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.6502 ORF CAL0003030 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.6502 ORF CAL0003030 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.6502 ORF CAL0003030 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.6506 ORF CAL0003038 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.6506 ORF CAL0003038 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.6506 ORF CAL0003038 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.6506 ORF CAL0003038 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.6506 ORF CAL0003038 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.6507 ORF CAL0003041 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.6507 ORF CAL0003041 PMID: 21414038|CGD_REF: CAL0141808 homozygous diploid, classical genetics null BWP17 viable C. albicans orf19.6507 ORF CAL0003041 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 invasive growth: decreased solid SLAD media C. albicans orf19.651 ORF LYP1 CAL0001027 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.6511 ORF LIG1 CAL0003070 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.6511 ORF LIG1 CAL0003070 PMID: 21135205|CGD_REF: CAL0139967 heterozygous diploid, large-scale survey (large-scale identification of genes essential for virulence in mouse) repressible CAI-4 virulence: absent mouse intravenous infection C. albicans orf19.6512 ORF EXO70 CAL0003072 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.6514 ORF CUP9 CAL0003077 PMID: 20041210|CGD_REF: CAL0124764 homozygous diploid, systematic mutation set null SN152 colony appearance: abnormal Spider medium at 30 deg C enhanced peripheral invasion C. albicans orf19.6514 ORF CUP9 CAL0003077 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.6514 ORF CUP9 CAL0003077 PMID: 21414038|CGD_REF: CAL0141808 homozygous diploid, classical genetics null BWP17 viable C. albicans orf19.6514 ORF CUP9 CAL0003077 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.6514 ORF CUP9 CAL0003077 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.6514 ORF CUP9 CAL0003077 PMID: 23808664|CGD_REF: CAL0000172530 homozygous diploid, systematic mutation set null CAI-4 filamentous growth: increased Lee's glucose medium at 25 deg opaque cells C. albicans orf19.6514 ORF CUP9 CAL0003077 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.6515 ORF HSP90 CAL0003079 PMID: 19327993|CGD_REF: CAL0122626 heterozygous diploid, classical genetics repressible SN95 germ tube formation: increased C. albicans orf19.6515 ORF HSP90 CAL0003079 PMID: 7591093|CGD_REF: CAL0081410 heterozygous diploid, classical genetics null Not recorded germ tube formation: normal liquid YPD plus serum at 37 deg C C. albicans orf19.6515 ORF HSP90 CAL0003079 PMID: 19115836|CGD_REF: CAL0122036 heterozygous diploid, competitive growth (haploinsufficient phenotype assay, barcode deletion set) null SC5314 resistance to chemicals: decreased virgineone C. albicans orf19.6515 ORF HSP90 CAL0003079 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.6515 ORF HSP90 CAL0003079 PMID: 7591093|CGD_REF: CAL0081410 heterozygous diploid, classical genetics null Not recorded viable wild-type growth rate C. albicans orf19.6515 ORF HSP90 CAL0003079 PMID: 7591093|CGD_REF: CAL0081410 homozygous diploid, classical genetics null Not recorded inviable homozygous null mutant strain could not be recovered, suggesting that the gene is essential under the selection conditions C. albicans orf19.6515 ORF HSP90 CAL0003079 PMID: 19649312|CGD_REF: CAL0123929 heterozygous diploid, classical genetics repressible Not recorded resistance to chemicals: decreased micafungin (30 ng/ml) micafungin treatment is fungicidal C. albicans orf19.6515 ORF HSP90 CAL0003079 PMID: 19196973|CGD_REF: CAL0122319 heterozygous diploid, classical genetics repressible Not recorded resistance to chemicals: decreased fluconazole mutant that does not show wild-type heat- or drug-responsive stress-mediated induction shows increased fluconazole sensitivity in vitro, and in murine intravenous infection (tetO-HSP90/hsp90del strain) C. albicans orf19.6515 ORF HSP90 CAL0003079 PMID: 22090345|CGD_REF: CAL0000143625 heterozygous diploid, classical genetics repressible SC5314 filamentous growth: abnormal C. albicans orf19.6515 ORF HSP90 CAL0003079 PMID: 22090345|CGD_REF: CAL0000143625 heterozygous diploid, classical genetics repressible SC5314 cellular morphology: abnormal C. albicans orf19.6515 ORF HSP90 CAL0003079 PMID: 22365851|CGD_REF: CAL0000144076 heterozygous diploid, classical genetics repressible tetO-HSP90/hsp90::CdHIS1 (doxicyclin-repressible conditional mutant) SN95 filamentous growth: increased DOX-mediated depletion of Hsp90 induces filamentation C. albicans orf19.6515 ORF HSP90 CAL0003079 PMID: 21931556|CGD_REF: CAL0000142969 heterozygous diploid, classical genetics repressible tetO-HSP90/hsp90 SN95 protein/peptide accumulation: decreased doxycycline-mediated reduction of Hsp90 levels led to an ~90% reduction in Cna1-His-FLAG in planktonic conditions, but no reduction in biofilm cells Cna1p C. albicans orf19.6515 ORF HSP90 CAL0003079 PMID: 21931556|CGD_REF: CAL0000142969 heterozygous diploid, classical genetics repressible tetO-HSP90/hsp90 (doxycyclin-repressible conditional mutant) SN95 resistance to chemicals: decreased fluconazole required for the resistance of biofilms to fluconazole in a mammalian host, compromise of Hsp90 function genetically or pharmacologically enhances the efficacy of fluconazole in vivo other model (rat central venous catheter infection) C. albicans orf19.6515 ORF HSP90 CAL0003079 PMID: 21931556|CGD_REF: CAL0000142969 heterozygous diploid, classical genetics null tetO-HSP90/hsp90 SN95 chemical compound accumulation: decreased glucan Hsp90 depletion leads to reduced glucan levels C. albicans orf19.6515 ORF HSP90 CAL0003079 PMID: 21931556|CGD_REF: CAL0000142969 heterozygous diploid, classical genetics repressible tetO-HSP90/hsp90 (doxycyclin-repressible conditional mutant) SN95 biofilm formation: abnormal abnormal biofilm in vitro, decreased thickness of the bottom yeast layer, biofilms formed upon Hsp90 genetic or chemical inhibition with geldanamycin have a greater proportion of their total thickness occupied by filaments C. albicans orf19.6515 ORF HSP90 CAL0003079 PMID: 23028789|CGD_REF: CAL0000157931 heterozygous diploid, classical genetics repressible tetO-HSP90/hsp90 SN95 apoptosis: decreased repressive conditions, doxycycline or tetracycline C. albicans orf19.6515 ORF HSP90 CAL0003079 PMID: 21931556|CGD_REF: CAL0000142969 heterozygous diploid, classical genetics repressible tetO-HSP90/hsp90 SN95 protein/peptide accumulation: decreased doxycycline-mediated reduction of Hsp90 levels led to ~80% reduction in Mkc1 levels in planktonic conditions, however, Mkc1 levels remain stable in biofilm conditions Mkc1p C. albicans orf19.6515 ORF HSP90 CAL0003079 PMID: 21931556|CGD_REF: CAL0000142969 heterozygous diploid, classical genetics repressible tetO-HSP90/hsp90 SN95 protein/peptide modification: decreased doxycycline-mediated reduction of Hsp90 leads to a reduction in levels of activated Mkc1 in planktonic conditions, however, Mkc1 remains activated in biofilm conditions Mkc1p C. albicans orf19.6515 ORF HSP90 CAL0003079 PMID: 19196973|CGD_REF: CAL0122319 heterozygous diploid, classical genetics repressible Not recorded virulence: decreased decreased fungal burden (tetO-HSP90/hsp90del strain, nonrepressing conditions) mouse intravenous infection C. albicans orf19.6515 ORF HSP90 CAL0003079 PMID: 19649312|CGD_REF: CAL0123929 heterozygous diploid, classical genetics repressible Not recorded virulence: decreased exhibits decreased kidney colonization mouse intravenous infection C. albicans orf19.6515 ORF HSP90 CAL0003079 PMID: 19196973|CGD_REF: CAL0122319 heterozygous diploid, classical genetics null Not recorded virulence: normal wild-type fungal burden mouse intravenous infection C. albicans orf19.6515 ORF HSP90 CAL0003079 PMID: 19327993|CGD_REF: CAL0122626 heterozygous diploid, classical genetics repressible Not recorded virulence: decreased mouse intravenous infection C. albicans orf19.6517 ORF RAD14 CAL0003083 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.6518 ORF CAL0003085 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.6522 ORF CAL0003114 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.6524 ORF TOM40 CAL0003116 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.6524 ORF TOM40 CAL0003116 PMID: 21135205|CGD_REF: CAL0139967 heterozygous diploid, large-scale survey (large-scale identification of genes essential for virulence in mouse) repressible CAI-4 virulence: absent mouse intravenous infection C. albicans orf19.6526 ORF CAL0003122 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.6526 ORF CAL0003122 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: abnormal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.6526 ORF CAL0003122 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.6526 ORF CAL0003122 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.6529 ORF CDC34 CAL0003131 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.6530 ORF CAL0003143 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.6530 ORF CAL0003143 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.6530 ORF CAL0003143 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.6530 ORF CAL0003143 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.6531 ORF NUC2 CAL0003145 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.6531 ORF NUC2 CAL0003145 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient SC medium C. albicans orf19.6531 ORF NUC2 CAL0003145 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient SLAD medium C. albicans orf19.6532 ORF CAL0003146 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.6533 ORF MSK1 CAL0003148 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.6534 ORF CAL0003151 PMID: 24610660|CGD_REF: CAL0000173793 homozygous diploid, classical genetics null BWP17 viable C. albicans orf19.6534.2 ORF CRN1 CAF0007082 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 invasive growth: decreased solid SLAD media C. albicans orf19.6536 ORF IQG1 CAL0003156 PMID: 18923418|CGD_REF: CAL0120369 homozygous diploid, classical genetics null Not recorded heat sensitivity: increased heat enhances morphology defects; cells are inviable at 42 deg C. albicans orf19.6536 ORF IQG1 CAL0003156 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.6536 ORF IQG1 CAL0003156 PMID: 18923418|CGD_REF: CAL0120369 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.6536 ORF IQG1 CAL0003156 PMID: 18923418|CGD_REF: CAL0120369 homozygous diploid, classical genetics null Not recorded bud neck morphology: abnormal bud necks are enlarged C. albicans orf19.6536 ORF IQG1 CAL0003156 PMID: 18923418|CGD_REF: CAL0120369 homozygous diploid, classical genetics null Not recorded cell shape: abnormal cells are elongated; phenotype also results from phosphorylation site disruption or phosphomimetic mutations C. albicans orf19.6536 ORF IQG1 CAL0003156 PMID: 18923418|CGD_REF: CAL0120369 homozygous diploid, classical genetics null Not recorded cell size: increased C. albicans orf19.6536 ORF IQG1 CAL0003156 PMID: 18923418|CGD_REF: CAL0120369 homozygous diploid, classical genetics null Not recorded cytokinesis: absent chains of cells observed C. albicans orf19.6536 ORF IQG1 CAL0003156 PMID: 18923418|CGD_REF: CAL0120369 homozygous diploid, classical genetics null Not recorded cytoskeleton morphology: abnormal actomyosin ring defect C. albicans orf19.6537 ORF CAL0003159 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.6538 ORF VMA11 CAL0003162 PMID: 18466294|CGD_REF: CAL0119004 homozygous diploid, classical genetics null Not recorded vegetative growth: decreased rate neutral pH C. albicans orf19.6538 ORF VMA11 CAL0003162 PMID: 18466294|CGD_REF: CAL0119004 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.6538 ORF VMA11 CAL0003162 PMID: 18466294|CGD_REF: CAL0119004 homozygous diploid, classical genetics null Not recorded utilization of iron source: absent hemoglobin C. albicans orf19.6539 ORF CAL0003165 PMID: 19115836|CGD_REF: CAL0122036 heterozygous diploid, competitive growth (haploinsufficient phenotype assay, barcode deletion set) null SC5314 resistance to chemicals: decreased virgineone C. albicans orf19.6539 ORF CAL0003165 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.6541 ORF RPL5 CAL0003181 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.6544 ORF LPI9 CAL0003186 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.6548 ORF ISU1 CAL0003195 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.6551 ORF CAL0003205 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.6551.1 ORF STE18 CAF0007083 PMID: 24489040|CGD_REF: CAL0000173772 homozygous diploid, classical genetics null Other C. albicans viable C. albicans orf19.6551.1 ORF STE18 CAF0007083 PMID: 24489040|CGD_REF: CAL0000173772 homozygous diploid, classical genetics null Other C. albicans sterile C. albicans orf19.6552 ORF CAL0003207 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 invasive growth: decreased solid SLAD media C. albicans orf19.6553 ORF CAL0003209 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.6553 ORF CAL0003209 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.6553 ORF CAL0003209 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.6553 ORF CAL0003209 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.6557 ORF CAL0003221 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.6558 ORF CAL0003224 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.6559 ORF CAL0003226 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.6559 ORF CAL0003226 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 invasive growth: decreased solid SLAD media C. albicans orf19.6561 ORF LAT1 CAL0003237 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.6562 ORF RNH35 CAL0003240 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.6563 ORF KCH1 CAL0003243 PMID: 24142703|CGD_REF: CAL0000173075 haploid, classical genetics null SC5314 viable C. albicans orf19.6563 ORF KCH1 CAL0003243 PMID: 24142703|CGD_REF: CAL0000173075 haploid, classical genetics null SC5314 nutrient uptake: decreased calcium(2+) with tunicamycin and FK506 C. albicans orf19.6565 ORF CAL0003249 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.6568 ORF SMC6 CAL0003255 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.6569 ORF CAL0003258 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.6569 ORF CAL0003258 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 invasive growth: decreased solid SLAD media C. albicans orf19.657 ORF SAM2 CAL0001034 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.6570 ORF NUP CAL0003267 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.6573 ORF BEM2 CAL0003273 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 invasive growth: decreased solid SLAD media C. albicans orf19.6574 ORF ALK6 CAL0003277 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.6577 ORF FLU1 CAL0003286 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.6577 ORF FLU1 CAL0003286 PMID: 11065353|CGD_REF: CAL0080815 heterozygous diploid, classical genetics null Not recorded viable C. albicans orf19.6577 ORF FLU1 CAL0003286 PMID: 11065353|CGD_REF: CAL0080815 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.6577 ORF FLU1 CAL0003286 PMID: 11065353|CGD_REF: CAL0080815 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased mycophenolic acid C. albicans orf19.6577 ORF FLU1 CAL0003286 PMID: 23380720|CGD_REF: CAL0000158492 homozygous diploid, classical genetics null CAF2-1 toxin resistance: decreased human salivary histatin 5 C. albicans orf19.6577 ORF FLU1 CAL0003286 PMID: 23380720|CGD_REF: CAL0000158492 homozygous diploid, classical genetics null CAF2-1 chemical compound excretion: decreased spermidine C. albicans orf19.6578 ORF CAL0003288 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.6578 ORF CAL0003288 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.6578 ORF CAL0003288 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.6578 ORF CAL0003288 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.658 ORF GIN1 CAL0001036 PMID: 17182857|CGD_REF: CAL0117321 homozygous diploid, classical genetics null Not recorded vegetative growth: decreased rate C. albicans orf19.658 ORF GIN1 CAL0001036 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.658 ORF GIN1 CAL0001036 PMID: 14663094|CGD_REF: CAL0080633 homozygous diploid, systematic mutation set (homozygous insertion mutants generated with URA3-ARG4-URA3 (UAU1) cassette) null BWP17 viable C. albicans orf19.658 ORF GIN1 CAL0001036 PMID: 17182857|CGD_REF: CAL0117321 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.658 ORF GIN1 CAL0001036 PMID: 17182857|CGD_REF: CAL0117321 homozygous diploid, classical genetics null Not recorded cell shape: abnormal cells are elongated C. albicans orf19.658 ORF GIN1 CAL0001036 PMID: 17182857|CGD_REF: CAL0117321 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased methyl methanesulfonate C. albicans orf19.658 ORF GIN1 CAL0001036 PMID: 17182857|CGD_REF: CAL0117321 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased hydroxyurea C. albicans orf19.6582 ORF PRE10 CAL0003302 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.6584 ORF PRT1 CAL0003307 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, competitive growth (haploinsufficient phenotype assay, barcode deletion set) null SC5314 resistance to chemicals: decreased verrucarin C. albicans orf19.6584 ORF PRT1 CAL0003307 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, competitive growth (haploinsufficient phenotype assay, barcode deletion set) null SC5314 resistance to chemicals: decreased roridin A C. albicans orf19.6584 ORF PRT1 CAL0003307 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.6586 ORF CAL0003313 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, competitive growth (haploinsufficient phenotype assay, barcode deletion set) null SC5314 resistance to chemicals: decreased 5-fluorouracil C. albicans orf19.6586 ORF CAL0003313 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, competitive growth (haploinsufficient phenotype assay, barcode deletion set) null SC5314 resistance to chemicals: decreased tubercidin C. albicans orf19.6586 ORF CAL0003313 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.6587 ORF GIR2 CAL0003315 PMID: 12773383|CGD_REF: CAL0087974 heterozygous diploid, classical genetics (haploinsufficient phenotype assay) unspecified CAI-4 filamentous growth: decreased solid Spider medium transposon insertion proximal to, but not within, the ORF C. albicans orf19.6587 ORF GIR2 CAL0003315 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 invasive growth: decreased solid SLAD media C. albicans orf19.6588 ORF NBP2 CAL0003317 PMID: 20383711|CGD_REF: CAL0125351 homozygous diploid, classical genetics null nbp2::CdHIS1/nbp2::URA3 SC5314 viable C. albicans orf19.6588 ORF NBP2 CAL0003317 PMID: 20383711|CGD_REF: CAL0125351 homozygous diploid, classical genetics null nbp2::CdHIS1/nbp2::URA3 SC5314 hyphal growth: abnormal serum-containing or Spider medium shorter hyphae and multiple germ tubes C. albicans orf19.6588 ORF NBP2 CAL0003317 PMID: 20383711|CGD_REF: CAL0125351 homozygous diploid, classical genetics null nbp2::CdHIS1/nbp2::URA3 SC5314 germ tube formation: abnormal serum-containing or Spider medium shorter hyphae and multiple germ tubes C. albicans orf19.6588 ORF NBP2 CAL0003317 PMID: 20383711|CGD_REF: CAL0125351 homozygous diploid, classical genetics null nbp2::CdHIS1/nbp2::URA3 SC5314 vacuolar morphology: abnormal fragmented vacuoles in hyphae, but normal in yeast cells C. albicans orf19.6592 ORF CAL0003332 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.6592 ORF CAL0003332 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.6592 ORF CAL0003332 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.6592 ORF CAL0003332 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.6592 ORF CAL0003332 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.6594 ORF PLB3 CAL0003334 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.6595 ORF RTA4 CAL0003337 PMID: 12773383|CGD_REF: CAL0087974 heterozygous diploid, classical genetics (haploinsufficient phenotype assay) unspecified CAI-4 filamentous growth: decreased solid Spider medium transposon insertion proximal to, but not within, the ORF C. albicans orf19.6595 ORF RTA4 CAL0003337 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.6596 ORF CAL0003339 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.6598 ORF WAL1 CAL0003342 PMID: 16215178|CGD_REF: CAL0114839 homozygous diploid, classical genetics null Not recorded filamentous growth: absent C. albicans orf19.6598 ORF WAL1 CAL0003342 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.6598 ORF WAL1 CAL0003342 PMID: 15075276|CGD_REF: CAL0082031 homozygous diploid, classical genetics null BWP17 hyphal growth: absent solid Spider or serum-containing media C. albicans orf19.6598 ORF WAL1 CAL0003342 PMID: 16215178|CGD_REF: CAL0114839 homozygous diploid, classical genetics null Not recorded endocytosis: abnormal C. albicans orf19.6598 ORF WAL1 CAL0003342 PMID: 16215178|CGD_REF: CAL0114839 homozygous diploid, classical genetics null Not recorded endomembrane system morphology: abnormal vesicle accumulation at germ tube tip C. albicans orf19.6598 ORF WAL1 CAL0003342 PMID: 15075276|CGD_REF: CAL0082031 homozygous diploid, classical genetics null wal1::URA3/wal1::HIS1, arg4 BWP17 budding pattern: abnormal C. albicans orf19.6598 ORF WAL1 CAL0003342 PMID: 15075276|CGD_REF: CAL0082031 homozygous diploid, classical genetics null wal1::URA3/wal1::HIS1, arg4 BWP17 viable C. albicans orf19.6598 ORF WAL1 CAL0003342 PMID: 15075276|CGD_REF: CAL0082031 homozygous diploid, classical genetics null wal1::URA3/wal1::HIS1, arg4 BWP17 filamentous growth: absent C. albicans orf19.6598 ORF WAL1 CAL0003342 PMID: 15075276|CGD_REF: CAL0082031 homozygous diploid, classical genetics null wal1::URA3/wal1::HIS1, arg4 BWP17 actin cytoskeleton morphology: abnormal depolarization of actin patches C. albicans orf19.6598 ORF WAL1 CAL0003342 PMID: 15075276|CGD_REF: CAL0082031 heterozygous diploid, classical genetics null wal1::URA3/wal1::HIS1, arg4 BWP17 viable C. albicans orf19.6598 ORF WAL1 CAL0003342 PMID: 15075276|CGD_REF: CAL0082031 homozygous diploid, classical genetics null wal1::URA3/wal1::HIS1, arg4 BWP17 viable C. albicans orf19.6598 ORF WAL1 CAL0003342 PMID: 15075276|CGD_REF: CAL0082031 heterozygous diploid, classical genetics null WAL1/wal1::HIS1 BWP17 cellular morphology: normal C. albicans orf19.6598 ORF WAL1 CAL0003342 PMID: 15075276|CGD_REF: CAL0082031 homozygous diploid, classical genetics null wal1::URA3/wal1::HIS1, arg4 BWP17 cytokinesis: absent C. albicans orf19.6598 ORF WAL1 CAL0003342 PMID: 15075276|CGD_REF: CAL0082031 homozygous diploid, classical genetics null wal1::URA3/wal1::HIS1, arg4 BWP17 endocytosis: abnormal C. albicans orf19.6598 ORF WAL1 CAL0003342 PMID: 15075276|CGD_REF: CAL0082031 homozygous diploid, classical genetics null wal1::URA3/wal1::HIS1, arg4 BWP17 cell shape: abnormal cells are round C. albicans orf19.6598 ORF WAL1 CAL0003342 PMID: 15075276|CGD_REF: CAL0082031 homozygous diploid, classical genetics null wal1::URA3/wal1::HIS1, arg4 BWP17 cell size: increased abnormal expansion of mother cell C. albicans orf19.6598 ORF WAL1 CAL0003342 PMID: 15075276|CGD_REF: CAL0082031 homozygous diploid, classical genetics null wal1::URA3/wal1::HIS1, arg4 BWP17 endocytosis: abnormal C. albicans orf19.6598 ORF WAL1 CAL0003342 PMID: 15075276|CGD_REF: CAL0082031 homozygous diploid, classical genetics null wal1::URA3/wal1::HIS1, arg4 BWP17 heat sensitivity: normal C. albicans orf19.6598 ORF WAL1 CAL0003342 PMID: 15075276|CGD_REF: CAL0082031 homozygous diploid, classical genetics null wal1::URA3/wal1::HIS1, arg4 BWP17 pseudohyphal growth: abnormal pseudohyphal growth occurs under hyphal growth-inducing conditions C. albicans orf19.6598 ORF WAL1 CAL0003342 PMID: 15075276|CGD_REF: CAL0082031 homozygous diploid, classical genetics null wal1::URA3/wal1::HIS1, arg4 BWP17 vacuolar morphology: abnormal vacuoles are fragmented C. albicans orf19.6598 ORF WAL1 CAL0003342 PMID: 17139615|CGD_REF: CAL0117016 homozygous diploid, classical genetics null wal1::HIS1/wal1::URA3, arg4 BWP17 filamentous growth: absent mutants failed to filament upon contact with porcine intestinal epithelia ex vivo model of infection (Porcine Intestinal Epithelium (PIE)-Assay) C. albicans orf19.6598 ORF WAL1 CAL0003342 PMID: 17139615|CGD_REF: CAL0117016 homozygous diploid, classical genetics null wal1::HIS1/wal1::URA3, arg4 BWP17 virulence: decreased C. albicans orf19.660 ORF CAL0001052 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.660 ORF CAL0001052 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.660 ORF CAL0001052 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.660 ORF CAL0001052 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.6601.1 ORF YKE2 CAF0007113 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 invasive growth: decreased solid SLAD media C. albicans orf19.6602 ORF CAL0003918 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.6602 ORF CAL0003918 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 invasive growth: decreased solid SLAD media C. albicans orf19.6606 ORF CAL0003928 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.6606 ORF CAL0003928 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.6606 ORF CAL0003928 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.6606 ORF CAL0003928 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.6606 ORF CAL0003928 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.6607 ORF CAL0003931 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: decreased growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.6607 ORF CAL0003931 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: decreased rate liquid synthetic complete medium C. albicans orf19.6607 ORF CAL0003931 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.6607 ORF CAL0003931 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 invasive growth: decreased solid SLAD media C. albicans orf19.6608 ORF CAL0003933 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 invasive growth: decreased solid SLAD media C. albicans orf19.661 ORF KRR1 CAL0001053 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.661 ORF KRR1 CAL0001053 PMID: 21135205|CGD_REF: CAL0139967 heterozygous diploid, large-scale survey (large-scale identification of genes essential for virulence in mouse) repressible CAI-4 virulence: absent mouse intravenous infection C. albicans orf19.6610 ORF CAL0003948 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.6621 ORF MHP1 CAL0003977 PMID: 12773383|CGD_REF: CAL0087974 heterozygous diploid, classical genetics (haploinsufficient phenotype assay) unspecified CAI-4 filamentous growth: increased solid Spider medium transposon insertion proximal to, but not within, the ORF C. albicans orf19.6623 ORF CAL0003980 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient YPD medium C. albicans orf19.6623 ORF CAL0003980 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient YNB medium C. albicans orf19.6623 ORF CAL0003980 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient SLAD medium C. albicans orf19.6629 ORF ISC1 CAL0003997 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.6629 ORF ISC1 CAL0003997 PMID: 14663094|CGD_REF: CAL0080633 homozygous diploid, systematic mutation set (homozygous insertion mutants generated with URA3-ARG4-URA3 (UAU1) cassette) null BWP17 viable C. albicans orf19.663 ORF GIN4 CAL0001054 PMID: 14769857|CGD_REF: CAL0080845 homozygous diploid, classical genetics null Not recorded germ tube formation: abnormal primary septum is not formed in germ tube C. albicans orf19.663 ORF GIN4 CAL0001054 PMID: 14769857|CGD_REF: CAL0080845 heterozygous diploid, classical genetics repressible Not recorded germ tube formation: abnormal primary septum is not formed in germ tube C. albicans orf19.663 ORF GIN4 CAL0001054 PMID: 14769857|CGD_REF: CAL0080845 homozygous diploid, classical genetics null Not recorded septum formation: abnormal abnormal septin dynamics in germ tube C. albicans orf19.663 ORF GIN4 CAL0001054 PMID: 14769857|CGD_REF: CAL0080845 heterozygous diploid, classical genetics repressible Not recorded septum formation: abnormal abnormal septin dynamics in germ tube C. albicans orf19.663 ORF GIN4 CAL0001054 PMID: 14769857|CGD_REF: CAL0080845 heterozygous diploid, classical genetics repressible Not recorded septum formation: abnormal decreased formation of primary septum C. albicans orf19.663 ORF GIN4 CAL0001054 PMID: 14769857|CGD_REF: CAL0080845 heterozygous diploid, classical genetics repressible Not recorded septum formation: abnormal decreased formation of septin ring in germ tube C. albicans orf19.663 ORF GIN4 CAL0001054 PMID: 14769857|CGD_REF: CAL0080845 homozygous diploid, classical genetics null Not recorded vegetative growth: decreased rate C. albicans orf19.663 ORF GIN4 CAL0001054 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.663 ORF GIN4 CAL0001054 PMID: 14769857|CGD_REF: CAL0080845 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.663 ORF GIN4 CAL0001054 PMID: 14769857|CGD_REF: CAL0080845 heterozygous diploid, classical genetics overexpression Not recorded viable C. albicans orf19.663 ORF GIN4 CAL0001054 PMID: 14769857|CGD_REF: CAL0080845 heterozygous diploid, classical genetics repressible Not recorded viable C. albicans orf19.663 ORF GIN4 CAL0001054 PMID: 17765684|CGD_REF: CAL0118343 heterozygous diploid, classical genetics null Not recorded viable C. albicans orf19.663 ORF GIN4 CAL0001054 PMID: 17765684|CGD_REF: CAL0118343 heterozygous diploid, classical genetics repressible Not recorded viable C. albicans orf19.663 ORF GIN4 CAL0001054 PMID: 14769857|CGD_REF: CAL0080845 heterozygous diploid, classical genetics repressible Not recorded hyphal growth: normal serum-containing medium wild-type yeast to hyphal switch C. albicans orf19.663 ORF GIN4 CAL0001054 PMID: 14769857|CGD_REF: CAL0080845 homozygous diploid, classical genetics null BWP17 invasive growth: decreased 37 deg C C. albicans orf19.663 ORF GIN4 CAL0001054 PMID: 14769857|CGD_REF: CAL0080845 homozygous diploid, classical genetics null BWP17 invasive growth: increased YEPD medium at 30 deg C C. albicans orf19.663 ORF GIN4 CAL0001054 PMID: 14769857|CGD_REF: CAL0080845 heterozygous diploid, classical genetics repressible Not recorded cell shape: abnormal cells are elongated C. albicans orf19.663 ORF GIN4 CAL0001054 PMID: 14769857|CGD_REF: CAL0080845 homozygous diploid, classical genetics null Not recorded cell shape: abnormal cells are elongated and form chains C. albicans orf19.663 ORF GIN4 CAL0001054 PMID: 17765684|CGD_REF: CAL0118343 heterozygous diploid, classical genetics repressible Not recorded cell shape: abnormal elongated cells linked in chains C. albicans orf19.663 ORF GIN4 CAL0001054 PMID: 14769857|CGD_REF: CAL0080845 heterozygous diploid, classical genetics repressible Not recorded nuclear position: abnormal C. albicans orf19.663 ORF GIN4 CAL0001054 PMID: 14769857|CGD_REF: CAL0080845 heterozygous diploid, classical genetics overexpression Not recorded pseudohyphal growth: abnormal serum-containing medium increased pseudohyphal to hyphal switching C. albicans orf19.663 ORF GIN4 CAL0001054 PMID: 14769857|CGD_REF: CAL0080845 homozygous diploid, classical genetics null Not recorded pseudohyphal growth: increased pseudohyphal growth is constitutive C. albicans orf19.663 ORF GIN4 CAL0001054 PMID: 14769857|CGD_REF: CAL0080845 homozygous diploid, classical genetics null Not recorded pseudohyphal growth: abnormal serum-containing media pseudohyphal growth occurs under hyphal growth-inducing conditions C. albicans orf19.663 ORF GIN4 CAL0001054 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: increased growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.663 ORF GIN4 CAL0001054 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: abnormal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.663 ORF GIN4 CAL0001054 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, classical genetics null SN152 germ tube formation: decreased serum-containing medium C. albicans orf19.663 ORF GIN4 CAL0001054 PMID: 22366454|CGD_REF: CAL0000144075 heterozygous diploid, classical genetics conditional BWP17 protein/peptide distribution: abnormal G1 cells released into the glucose (repressive) medium did not show bud-neck localization of Cdc12-GFP at any stage of the cell cycle; instead it localized persistently at the bud tip Cdc12-GFP C. albicans orf19.663 ORF GIN4 CAL0001054 PMID: 23856128|CGD_REF: CAL0000172540 homozygous diploid, classical genetics null BWP17 resistance to chemicals: decreased propolis C. albicans orf19.663 ORF GIN4 CAL0001054 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: decreased rate liquid synthetic complete medium C. albicans orf19.663 ORF GIN4 CAL0001054 PMID: 20140194|CGD_REF: CAL0124995 homozygous diploid, classical genetics null Other C. albicans resistance to chemicals: decreased caspofungin C. albicans orf19.663 ORF GIN4 CAL0001054 PMID: 20140194|CGD_REF: CAL0124995 homozygous diploid, classical genetics null Other C. albicans viable caspofungin C. albicans orf19.663 ORF GIN4 CAL0001054 PMID: 20140194|CGD_REF: CAL0124995 homozygous diploid, classical genetics null Other C. albicans protein/peptide distribution: abnormal mother-daughter cell bud-neck localization not observed in mutants Sep7-GFP C. albicans orf19.663 ORF GIN4 CAL0001054 PMID: 20140194|CGD_REF: CAL0124995 homozygous diploid, classical genetics null Other C. albicans viable C. albicans orf19.663 ORF GIN4 CAL0001054 PMID: 20140194|CGD_REF: CAL0124995 homozygous diploid, classical genetics null Other C. albicans oxidative stress resistance: decreased hydrogen peroxide C. albicans orf19.663 ORF GIN4 CAL0001054 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.6630 ORF CAF0007071 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 invasive growth: decreased solid SLAD media C. albicans orf19.6632 ORF ACO2 CAL0004005 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.6634 ORF VMA2 CAL0004009 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.6637 ORF CAL0004017 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.6637 ORF CAL0004017 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.6637 ORF CAL0004017 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.6637 ORF CAL0004017 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.6638 ORF PTC4 CAL0004020 PMID: 18708562|CGD_REF: CAL0119375 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.6638 ORF PTC4 CAL0004020 PMID: 20014041|CGD_REF: CAL0124744 homozygous diploid, classical genetics null RM1000 viable C. albicans orf19.6638 ORF PTC4 CAL0004020 PMID: 20014041|CGD_REF: CAL0124744 homozygous diploid, classical genetics null RM1000 metal resistance: decreased sodium C. albicans orf19.6638 ORF PTC4 CAL0004020 PMID: 20014041|CGD_REF: CAL0124744 homozygous diploid, classical genetics null RM1000 metal resistance: decreased potassium C. albicans orf19.6638 ORF PTC4 CAL0004020 PMID: 20014041|CGD_REF: CAL0124744 homozygous diploid, classical genetics null RM1000 resistance to chemicals: decreased fluconazole C. albicans orf19.6638 ORF PTC4 CAL0004020 PMID: 20014041|CGD_REF: CAL0124744 homozygous diploid, classical genetics null RM1000 resistance to chemicals: decreased ketoconazole C. albicans orf19.6638 ORF PTC4 CAL0004020 PMID: 18708562|CGD_REF: CAL0119375 homozygous diploid, classical genetics null Not recorded virulence: decreased insect infection C. albicans orf19.6640 ORF TPS1 CAL0004028 PMID: 15777624|CGD_REF: CAL0104039 homozygous diploid, classical genetics null Not recorded germ tube formation: increased serum-containing medium at 37 deg C C. albicans orf19.6640 ORF TPS1 CAL0004028 PMID: 9683476|CGD_REF: CAL0081981 homozygous diploid, classical genetics null Not recorded heat sensitivity: increased glucose-containing medium at 42 deg C C. albicans orf19.6640 ORF TPS1 CAL0004028 PMID: 9683476|CGD_REF: CAL0081981 homozygous diploid, classical genetics null Not recorded vegetative growth: normal rate galactose medium at 37 deg C C. albicans orf19.6640 ORF TPS1 CAL0004028 PMID: 9683476|CGD_REF: CAL0081981 homozygous diploid, classical genetics null Not recorded vegetative growth: normal rate galactose or glycerol media at 42 deg C C. albicans orf19.6640 ORF TPS1 CAL0004028 PMID: 9683476|CGD_REF: CAL0081981 homozygous diploid, classical genetics null Not recorded vegetative growth: normal rate glucose, fructose, galactose, or glycerol media at 30 deg C C. albicans orf19.6640 ORF TPS1 CAL0004028 PMID: 9683476|CGD_REF: CAL0081981 homozygous diploid, classical genetics null Not recorded vegetative growth: decreased rate glucose-containing medium at 37 deg C C. albicans orf19.6640 ORF TPS1 CAL0004028 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.6640 ORF TPS1 CAL0004028 PMID: 14507372|CGD_REF: CAL0088818 heterozygous diploid, large-scale survey (large-scale identification of essential genes by gene replacement and conditional expression (GRACE) method) repressible CAI-4 viable one allele is deleted and the other is placed under repressible Tet promoter C. albicans orf19.6640 ORF TPS1 CAL0004028 PMID: 9683476|CGD_REF: CAL0081981 heterozygous diploid, classical genetics null Not recorded viable C. albicans orf19.6640 ORF TPS1 CAL0004028 PMID: 9683476|CGD_REF: CAL0081981 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.6640 ORF TPS1 CAL0004028 PMID: 10577485|CGD_REF: CAL0081982 homozygous diploid, classical genetics null CAI-4 hyphal growth: abnormal carbon-source dependent defect in growth or hyphal induction on glucose or fructose media; mutant can form germ tubes in response to serum C. albicans orf19.6640 ORF TPS1 CAL0004028 PMID: 9683476|CGD_REF: CAL0081981 homozygous diploid, classical genetics null CAI-4 hyphal growth: absent liquid galactose or glycerol media at 42 deg C C. albicans orf19.6640 ORF TPS1 CAL0004028 PMID: 9683476|CGD_REF: CAL0081981 homozygous diploid, classical genetics null CAI-4 hyphal growth: normal liquid galactose or glycerol plus serum media at 37 deg C C. albicans orf19.6640 ORF TPS1 CAL0004028 PMID: 9683476|CGD_REF: CAL0081981 homozygous diploid, classical genetics null CAI-4 hyphal growth: absent liquid glucose plus serum media at 37 deg C C. albicans orf19.6640 ORF TPS1 CAL0004028 PMID: 9683476|CGD_REF: CAL0081981 homozygous diploid, classical genetics null Not recorded chemical compound accumulation: decreased ATP C. albicans orf19.6640 ORF TPS1 CAL0004028 PMID: 9683476|CGD_REF: CAL0081981 homozygous diploid, classical genetics null Not recorded utilization of carbon source: increased D-glucose increased glucose consumption C. albicans orf19.6640 ORF TPS1 CAL0004028 PMID: 10577485|CGD_REF: CAL0081982 homozygous diploid, classical genetics null CAI-4 chemical compound accumulation: absent trehalose defect in trehalose accumulation in response to oxidative, osmotic, or heat stress C. albicans orf19.6640 ORF TPS1 CAL0004028 PMID: 9683476|CGD_REF: CAL0081981 heterozygous diploid, classical genetics null Not recorded chemical compound accumulation: decreased trehalose phenotype is intermediate between that of wild type and the homozygous null mutant C. albicans orf19.6640 ORF TPS1 CAL0004028 PMID: 9683476|CGD_REF: CAL0081981 homozygous diploid, classical genetics null Not recorded chemical compound accumulation: absent trehalose C. albicans orf19.6640 ORF TPS1 CAL0004028 PMID: 21246042|CGD_REF: CAL0141194 homozygous diploid, classical genetics null tps1::hisG/tps1:hisG CAI-4 apoptosis: increased accelerated apoptosis in response to hydrogen peroxide C. albicans orf19.6640 ORF TPS1 CAL0004028 PMID: 21252202|CGD_REF: CAL0141206 homozygous diploid, classical genetics null CAI-4 induction of host response: decreased decreased TNF-alfpha production by macrophages when yeasts were grown in liquid medium but not on solid media C. albicans orf19.6640 ORF TPS1 CAL0004028 PMID: 21570449|CGD_REF: CAL0142016 homozygous diploid, classical genetics null Other C. albicans resistance to chemicals: decreased amphotericin B null mutant show a high degree of cell killing upon exposure to increasing amounts of amphotericin B C. albicans orf19.6640 ORF TPS1 CAL0004028 PMID: 21570449|CGD_REF: CAL0142016 homozygous diploid, classical genetics null Other C. albicans protein activity: increased catalase C. albicans orf19.6640 ORF TPS1 CAL0004028 PMID: 21570449|CGD_REF: CAL0142016 homozygous diploid, classical genetics null Other C. albicans protein activity: increased glutathione reductase C. albicans orf19.6640 ORF TPS1 CAL0004028 PMID: 17359322|CGD_REF: CAL0117459 homozygous diploid, classical genetics null CAI-4 resistance to killing by host cells: decreased 1.5-fold lower survival rate for tps1/tps1 strains than CAI4 in vitro model of infection (peritoneal macrophages pre-stimulated with interferon-gamma) C. albicans orf19.6640 ORF TPS1 CAL0004028 PMID: 17359322|CGD_REF: CAL0117459 homozygous diploid, classical genetics null CAI-4 resistance to phagocytosis: increased reduced adherence to macrophages is accompanied by a reduced ingestion rate in vitro model of infection (J774 macrophages) C. albicans orf19.6640 ORF TPS1 CAL0004028 PMID: 9683476|CGD_REF: CAL0081981 homozygous diploid, classical genetics null Not recorded virulence: decreased mouse intravenous infection C. albicans orf19.6640 ORF TPS1 CAL0004028 PMID: 17359322|CGD_REF: CAL0117459 homozygous diploid, classical genetics null CAI-4 adhesion: decreased J774 macrophages C. albicans orf19.6642 ORF CAL0004032 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.6643 ORF MCT1 CAL0004034 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.6648 ORF SDA1 CAL0004046 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.6649 ORF BRF1 CAL0004048 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.665 ORF NEP1 CAL0001059 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.665 ORF NEP1 CAL0001059 PMID: 11935223|CGD_REF: CAL0086410 heterozygous diploid, classical genetics null Not recorded viable C. albicans orf19.665 ORF NEP1 CAL0001059 PMID: 11935223|CGD_REF: CAL0086410 homozygous diploid, classical genetics null Not recorded inviable homozygous null mutant strain could not be recovered, suggesting that the gene is essential under the selection conditions C. albicans orf19.6652 ORF DBP8 CAL0004058 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.6652 ORF DBP8 CAL0004058 PMID: 12524333|CGD_REF: CAL0080691 homozygous diploid, systematic mutation set (homozygous insertion mutants generated with URA3-ARG4-URA3 (UAU1) cassette) null BWP17 inviable homozygous null mutant strain could not be recovered, suggesting that the gene is essential under the selection conditions C. albicans orf19.6652 ORF DBP8 CAL0004058 PMID: 21135205|CGD_REF: CAL0139967 heterozygous diploid, competitive growth (large-scale identification of genes essential for virulence in mouse) repressible CAI-4 virulence: decreased mouse intravenous infection C. albicans orf19.6653 ORF MTG2 CAL0004060 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.6653 ORF MTG2 CAL0004060 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.6653 ORF MTG2 CAL0004060 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: decreased rate liquid synthetic complete medium C. albicans orf19.6653 ORF MTG2 CAL0004060 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.6654 ORF CAL0004063 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.6654 ORF CAL0004063 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.6654 ORF CAL0004063 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.6654 ORF CAL0004063 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.6656 ORF CAL0004068 PMID: 22438810|CGD_REF: CAL0000156986 homozygous diploid, classical genetics null BWP17 virulence: decreased mutants have reduced capacity to damage oral epithelial cells in vitro model of infection (monolayers of oral epithelial cells) C. albicans orf19.6656 ORF CAL0004068 PMID: 22438810|CGD_REF: CAL0000156986 homozygous diploid, classical genetics null dur3::ARG4/dur3::HIS1 BWP17 viable C. albicans orf19.6656 ORF CAL0004068 PMID: 22438810|CGD_REF: CAL0000156986 homozygous diploid, classical genetics null dur3::ARG4/dur3::HIS1 BWP17 toxin resistance: increased histatin 5 C. albicans orf19.6656 ORF CAL0004068 PMID: 22438810|CGD_REF: CAL0000156986 homozygous diploid, classical genetics null dur3::ARG4/dur3::HIS1 BWP17 metal resistance: decreased silver(1+) nitrate (0.75 mM) 100- to 1000-fold reduction in growth of the mutant in comparison to the wild type C. albicans orf19.6656 ORF CAL0004068 PMID: 22438810|CGD_REF: CAL0000156986 homozygous diploid, classical genetics null dur3::ARG4/dur3::HIS1 BWP17 colony size: decreased mutant formed significantly smaller microcolonies than the wild type and complemented strains C. albicans orf19.6656 ORF CAL0004068 PMID: 22438810|CGD_REF: CAL0000156986 homozygous diploid, competitive growth null dur3::ARG4/dur3::HIS1 BWP17 filamentous growth: decreased agar containing 10% serum or 5% RPMI, on Spider or SLAD agar or by embedding in YPS agar mutant formed aberrant colonies which lacked the peripheral, invasive filaments observed for the wild type C. albicans orf19.6656 ORF CAL0004068 PMID: 22438810|CGD_REF: CAL0000156986 homozygous diploid, competitive growth null dur3::ARG4/dur3::HIS1 BWP17 virulence: delayed required for the rapid onset of symptomatic disseminated candidiasis; kidneys exhibited similar pathologies to wild type-infected mice with the presence of fungal filaments and neutrophil infiltrates mouse intravenous infection C. albicans orf19.6656 ORF CAL0004068 PMID: 22033918|CGD_REF: CAL0000143535 homozygous diploid, classical genetics null CAF2-1 toxin resistance: increased histatin 5 human salivary histatin 5 C. albicans orf19.6656 ORF CAL0004068 PMID: 22438810|CGD_REF: CAL0000156986 homozygous diploid, classical genetics null dur3::ARG4/dur3::HIS1 BWP17 resistance to chemicals: decreased Congo Red (450 micrograms/mL) C. albicans orf19.6659 ORF GAP6 CAL0004074 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.6660 ORF CAL0004080 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.6660 ORF CAL0004080 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.6660 ORF CAL0004080 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.6660 ORF CAL0004080 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.6662 ORF CAL0004083 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 invasive growth: decreased solid SLAD media C. albicans orf19.6665 ORF CAL0004089 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.6670 ORF CAC2 CAL0004103 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.6670 ORF CAC2 CAL0004103 PMID: 23417560|CGD_REF: CAL0000158588 homozygous diploid, classical genetics null cac2::FRT/cac2::FRT Other C. albicans viable C. albicans orf19.6670 ORF CAC2 CAL0004103 PMID: 23417560|CGD_REF: CAL0000158588 homozygous diploid, classical genetics null cac2::FRT/cac2::FRT Other C. albicans heat sensitivity: increased elevated temperatures (42 deg) C. albicans orf19.6670 ORF CAC2 CAL0004103 PMID: 23417560|CGD_REF: CAL0000158588 homozygous diploid, classical genetics null cac2::FRT/cac2::FRT Other C. albicans resistance to chemicals: decreased hydroxyurea C. albicans orf19.6670 ORF CAC2 CAL0004103 PMID: 23417560|CGD_REF: CAL0000158588 homozygous diploid, classical genetics null cac2::FRT/cac2::FRT Other C. albicans resistance to chemicals: decreased nicotinamide dinucleotide C. albicans orf19.6671 ORF LAP4 CAL0004105 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.6671 ORF LAP4 CAL0004105 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, competitive growth (haploinsufficient phenotype assay, barcode deletion set) null SC5314 resistance to chemicals: decreased amphotericin B C. albicans orf19.6672 ORF MDJ1 CAL0004107 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.6673 ORF HEX1 CAL0004108 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.6673 ORF HEX1 CAL0004108 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.6673 ORF HEX1 CAL0004108 PMID: 3327914|CGD_REF: CAL0081368 unknown ploidy, classical genetics unspecified Other C. albicans utilization of carbon source: absent N,N'-diacetylchitobiose C. albicans orf19.6673 ORF HEX1 CAL0004108 PMID: 3327914|CGD_REF: CAL0081368 unknown ploidy, classical genetics unspecified Other C. albicans viable C. albicans orf19.6673 ORF HEX1 CAL0004108 PMID: 3327914|CGD_REF: CAL0081368 unknown ploidy, classical genetics unspecified Other C. albicans virulence: decreased decreased virulence in unspecified mouse infection model other model C. albicans orf19.6673 ORF HEX1 CAL0004108 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.6673 ORF HEX1 CAL0004108 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.6673 ORF HEX1 CAL0004108 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.6674 ORF BTS1 CAL0004110 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.6676 ORF CAL0004115 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.6676 ORF CAL0004115 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient YPD medium C. albicans orf19.6676 ORF CAL0004115 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient SC medium C. albicans orf19.6676 ORF CAL0004115 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient YNB medium C. albicans orf19.6676 ORF CAL0004115 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient SLAD medium C. albicans orf19.6676 ORF CAL0004115 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 invasive growth: decreased solid SLAD media C. albicans orf19.6678 ORF CAL0004120 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.6678 ORF CAL0004120 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.6678 ORF CAL0004120 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.6678 ORF CAL0004120 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.6679 ORF CAL0004122 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.668 ORF TOS4 CAL0001066 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.668 ORF TOS4 CAL0001066 PMID: 19463063|CGD_REF: CAL0123630 homozygous diploid, systematic mutation set (split-marker transposon insertion strategy to disrupt both alleles) null BWP17 viable C. albicans orf19.668 ORF TOS4 CAL0001066 PMID: 19463063|CGD_REF: CAL0123630 homozygous diploid, systematic mutation set (split-marker transposon insertion strategy to disrupt both alleles) null BWP17 virulence: normal Toll mutant D. melanogaster invasive infection insect infection C. albicans orf19.6680 ORF FGR27 CAL0004128 PMID: 12773383|CGD_REF: CAL0087974 heterozygous diploid, classical genetics (haploinsufficient phenotype assay) null CAI-4 filamentous growth: increased solid Spider medium or solid YEPD plus serum heterozygous deletion C. albicans orf19.6680 ORF FGR27 CAL0004128 PMID: 12773383|CGD_REF: CAL0087974 heterozygous diploid, classical genetics (haploinsufficient phenotype assay) unspecified CAI-4 filamentous growth: increased solid Spider medium transposon insertion proximal to, but not within, the ORF C. albicans orf19.6680 ORF FGR27 CAL0004128 PMID: 12773383|CGD_REF: CAL0087974 heterozygous diploid, classical genetics (haploinsufficient phenotype assay) null CAI-4 viable heterozygous deletion C. albicans orf19.6680 ORF FGR27 CAL0004128 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.6680 ORF FGR27 CAL0004128 PMID: 15964282|CGD_REF: CAL0114274 homozygous diploid, systematic mutation set (split-marker transposon insertion strategy to disrupt both alleles) null BWP17 viable C. albicans orf19.6680 ORF FGR27 CAL0004128 PMID: 15964282|CGD_REF: CAL0114274 homozygous diploid, systematic mutation set (split-marker transposon insertion strategy to disrupt both alleles) null BWP17 biofilm formation: normal C. albicans orf19.6680 ORF FGR27 CAL0004128 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.6680 ORF FGR27 CAL0004128 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.6680 ORF FGR27 CAL0004128 PMID: 22359502|CGD_REF: CAL0000144048 homozygous diploid, classical genetics null BWP17 viable insertion mutant, independent SN152 deletion mutant strain also tested C. albicans orf19.6680 ORF FGR27 CAL0004128 PMID: 22359502|CGD_REF: CAL0000144048 homozygous diploid, classical genetics null BWP17 adhesion: decreased insertion mutant, independent SN152 deletion mutant strain also tested C. albicans orf19.6680 ORF FGR27 CAL0004128 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.6680 ORF FGR27 CAL0004128 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.6681 ORF CAL0004129 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.6681 ORF CAL0004129 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.6681 ORF CAL0004129 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.6681 ORF CAL0004129 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.6685 ORF ISY1 CAL0004135 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, competitive growth (haploinsufficient phenotype assay, barcode deletion set) null SC5314 resistance to chemicals: increased flucytosine C. albicans orf19.6685 ORF ISY1 CAL0004135 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.6686 ORF ENP2 CAL0004137 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, competitive growth (haploinsufficient phenotype assay, barcode deletion set) null SC5314 resistance to chemicals: increased 5-fluorouracil C. albicans orf19.6686 ORF ENP2 CAL0004137 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, competitive growth (haploinsufficient phenotype assay, barcode deletion set) null SC5314 resistance to chemicals: increased tubercidin C. albicans orf19.6686 ORF ENP2 CAL0004137 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, competitive growth (haploinsufficient phenotype assay, barcode deletion set) null SC5314 resistance to chemicals: increased flucytosine C. albicans orf19.6686 ORF ENP2 CAL0004137 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.6686 ORF ENP2 CAL0004137 PMID: 16607011|CGD_REF: CAL0115846 heterozygous diploid, classical genetics null SC5314 viable C. albicans orf19.6686 ORF ENP2 CAL0004137 PMID: 16607011|CGD_REF: CAL0115846 homozygous diploid, classical genetics null SC5314 inviable homozygous null mutant strain could not be recovered, suggesting that the gene is essential under the selection conditions C. albicans orf19.6686 ORF ENP2 CAL0004137 PMID: 16607011|CGD_REF: CAL0115846 heterozygous diploid, classical genetics repressible SC5314 inviable C. albicans orf19.6686 ORF ENP2 CAL0004137 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 invasive growth: decreased solid SLAD media C. albicans orf19.6688 ORF CAL0004140 PMID: 24610660|CGD_REF: CAL0000173793 homozygous diploid, classical genetics null BWP17 induction of host response: increased increased production of IL-1beta by infected host C. albicans orf19.6688 ORF CAL0004140 PMID: 24610660|CGD_REF: CAL0000173793 homozygous diploid, classical genetics null BWP17 viable C. albicans orf19.6688 ORF CAL0004140 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 invasive growth: decreased solid SLAD media C. albicans orf19.6689 ORF ARG4 CAL0004142 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.6689 ORF ARG4 CAL0004142 PMID: 3519855|CGD_REF: CAL0080773 unknown ploidy, classical genetics unspecified Other C. albicans viable C. albicans orf19.6689 ORF ARG4 CAL0004142 PMID: 8194754|CGD_REF: CAL0080661 unknown ploidy, classical genetics unspecified Other C. albicans viable C. albicans orf19.6689 ORF ARG4 CAL0004142 PMID: 8194754|CGD_REF: CAL0080661 unknown ploidy, classical genetics unspecified Other C. albicans auxotrophy arginine C. albicans orf19.6689 ORF ARG4 CAL0004142 PMID: 3519855|CGD_REF: CAL0080773 unknown ploidy, classical genetics unspecified Other C. albicans auxotrophy arginine C. albicans orf19.6689 ORF ARG4 CAL0004142 PMID: 11119495|CGD_REF: CAL0080774 heterozygous diploid, classical genetics null arg4::MPAr WO-1 viable C. albicans orf19.6689 ORF ARG4 CAL0004142 PMID: 20737428|CGD_REF: CAL0126182 homozygous diploid, classical genetics null SC5314 viable phenotype is also observed in the WO-1 background C. albicans orf19.6689 ORF ARG4 CAL0004142 PMID: 20737428|CGD_REF: CAL0126182 homozygous diploid, classical genetics null SC5314 auxotrophy arginine phenotype is also observed in the WO-1 background C. albicans orf19.669 ORF PRM1 CAL0001069 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.669 ORF PRM1 CAL0001069 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.669 ORF PRM1 CAL0001069 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.669 ORF PRM1 CAL0001069 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.669 ORF PRM1 CAL0001069 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.6691 ORF CAL0004147 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.6692 ORF MNN26 CAL0004148 PMID: 23633946|CGD_REF: CAL0000172007 homozygous diploid, classical genetics null mnn26::dpl200/mnn26::dpl200 CAI-4 resistance to chemicals: decreased Calcofluor White YPD agar plates containing 100 ug/ml CFW C. albicans orf19.6692 ORF MNN26 CAL0004148 PMID: 23633946|CGD_REF: CAL0000172007 homozygous diploid, classical genetics null mnn26::dpl200/mnn26::dpl200 CAI-4 thermotolerance: decreased YPD agar plates incubated at 42 degrees C C. albicans orf19.6692 ORF MNN26 CAL0004148 PMID: 23633946|CGD_REF: CAL0000172007 homozygous diploid, classical genetics null mnn26::dpl200/mnn26::dpl200 CAI-4 resistance to chemicals: decreased sodium dodecyl sulfate YPD agar plates containing 0.03% SDS, 30 degrees C minor defect in resistance C. albicans orf19.6692 ORF MNN26 CAL0004148 PMID: 23633946|CGD_REF: CAL0000172007 homozygous diploid, classical genetics null mnn26::dpl200/mnn26::dpl200 CAI-4 chemical compound accumulation: increased glucan C. albicans orf19.6692 ORF MNN26 CAL0004148 PMID: 23633946|CGD_REF: CAL0000172007 homozygous diploid, classical genetics null mnn26::dpl200/mnn26::dpl200 CAI-4 chemical compound accumulation: decreased mannan C. albicans orf19.6692 ORF MNN26 CAL0004148 PMID: 23633946|CGD_REF: CAL0000172007 homozygous diploid, classical genetics null mnn26::dpl200/mnn26 CAI-4 induction of host response: decreased deletion of MNN26 resulted in a 50% reduction in TNF-alpha secretion from PBMCs C. albicans orf19.6693 ORF CAL0004149 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.6693 ORF CAL0004149 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.6693 ORF CAL0004149 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.6693 ORF CAL0004149 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.6693 ORF CAL0004149 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.6694 ORF CAL0004151 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.6694 ORF CAL0004151 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient YPD medium C. albicans orf19.6694 ORF CAL0004151 PMID: 20494978|CGD_REF: CAL0125636 heterozygous diploid, classical genetics null BWP17 resistance to chemicals: decreased clotrimazole (75 uM) growth in liquid culture confirmation of mutant phenotypes for heterozygous transposon insertion strains showing sensitivity in a large-scale assay C. albicans orf19.6696 ORF TIM9 CAL0004154 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.6699 ORF CAL0004159 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.670 ORF SMT3 CAL0001089 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.670 ORF SMT3 CAL0001089 PMID: 21209325|CGD_REF: CAL0140079 homozygous diploid, classical genetics null smt3/smt3 BWP17 viable C. albicans orf19.670 ORF SMT3 CAL0001089 PMID: 21209325|CGD_REF: CAL0140079 homozygous diploid, classical genetics null smt3/smt3 BWP17 protein/peptide modification: decreased phosphorylation Mkc1p C. albicans orf19.670 ORF SMT3 CAL0001089 PMID: 21209325|CGD_REF: CAL0140079 homozygous diploid, classical genetics null smt3/smt3 BWP17 hyphal growth: abnormal 10% serum at 37 degrees C unable to form true hyphae C. albicans orf19.670 ORF SMT3 CAL0001089 PMID: 21209325|CGD_REF: CAL0140079 homozygous diploid, classical genetics null smt3/smt3 BWP17 chitin deposition: abnormal revealed by Calcofluor White staining C. albicans orf19.670 ORF SMT3 CAL0001089 PMID: 21209325|CGD_REF: CAL0140079 homozygous diploid, classical genetics null smt3/smt3 BWP17 heat sensitivity: increased heat shock at 30, 37 and 42 degrees C C. albicans orf19.670 ORF SMT3 CAL0001089 PMID: 21209325|CGD_REF: CAL0140079 heterozygous diploid, classical genetics repressible MET3p-SMT3/smt3 BWP17 resistance to chemicals: decreased tunicamycin|Calcofluor White|Congo Red|caspofungin|hydrogen peroxide|sodium chloride C. albicans orf19.670 ORF SMT3 CAL0001089 PMID: 21209325|CGD_REF: CAL0140079 homozygous diploid, classical genetics null smt3/smt3 BWP17 resistance to chemicals: decreased tunicamycin|Calcofluor White|Congo Red|caspofungin|hydrogen peroxide|sodium chloride C. albicans orf19.670 ORF SMT3 CAL0001089 PMID: 21209325|CGD_REF: CAL0140079 heterozygous diploid, classical genetics repressible MET3p-SMT3/smt3 BWP17 heat sensitivity: increased heat shock at 30, 37 and 42 degrees C C. albicans orf19.6701 ORF CAL0004698 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.6702 ORF DED81 CAL0004700 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.6705 ORF CAL0004707 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.6705 ORF CAL0004707 PMID: 19779551|CGD_REF: CAL0124331 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.6705 ORF CAL0004707 PMID: 19779551|CGD_REF: CAL0124331 homozygous diploid, classical genetics null Not recorded colony appearance: abnormal solid Spider medium C. albicans orf19.6712 ORF CAL0004744 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient SC medium C. albicans orf19.6713 ORF CAL0004746 PMID: 22581526|CGD_REF: CAL0000157314 homozygous diploid, systematic mutation set null BWP17 resistance to chemicals: decreased flucytosine C. albicans orf19.6713 ORF CAL0004746 PMID: 22581526|CGD_REF: CAL0000157314 homozygous diploid, systematic mutation set null BWP17 resistance to chemicals: decreased amphotericin B C. albicans orf19.6713 ORF CAL0004746 PMID: 22581526|CGD_REF: CAL0000157314 homozygous diploid, systematic mutation set null BWP17 resistance to chemicals: decreased fluconazole C. albicans orf19.6713 ORF CAL0004746 PMID: 22581526|CGD_REF: CAL0000157314 homozygous diploid, systematic mutation set null BWP17 resistance to chemicals: decreased caspofungin C. albicans orf19.6716 ORF ABD1 CAL0004754 PMID: 12477801|CGD_REF: CAL0080831 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased Hygromycin B C. albicans orf19.6716 ORF ABD1 CAL0004754 PMID: 12477801|CGD_REF: CAL0080831 homozygous diploid, classical genetics null Not recorded vegetative growth: decreased rate growth defect is more severe at 37 deg C than at 30 deg C C. albicans orf19.6716 ORF ABD1 CAL0004754 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.6716 ORF ABD1 CAL0004754 PMID: 12477801|CGD_REF: CAL0080831 heterozygous diploid, classical genetics null Not recorded viable C. albicans orf19.6716 ORF ABD1 CAL0004754 PMID: 12477801|CGD_REF: CAL0080831 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.6719 ORF CAL0004765 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.6719 ORF CAL0004765 PMID: 20141603|CGD_REF: CAL0124951 homozygous diploid, systematic mutation set (homozygous insertion mutants generated with URA3-ARG4-URA3 (UAU1) cassette) null BWP17 colony appearance: abnormal 10% serum or Spider media at 37 deg C colonies are smoother than wild type but mutant is able to form true hyphae under liquid inducing conditions C. albicans orf19.6719 ORF CAL0004765 PMID: 20141603|CGD_REF: CAL0124951 homozygous diploid, systematic mutation set (homozygous insertion mutants generated with URA3-ARG4-URA3 (UAU1) cassette) null BWP17 viable C. albicans orf19.672 ORF CAL0001091 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.6720 ORF CAL0004785 PMID: 12773383|CGD_REF: CAL0087974 heterozygous diploid, classical genetics (haploinsufficient phenotype assay) unspecified CAI-4 filamentous growth: increased solid Spider medium C. albicans orf19.6720 ORF CAL0004785 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.6720 ORF CAL0004785 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.6720 ORF CAL0004785 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.6720 ORF CAL0004785 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.6722 ORF CAL0004788 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.6724 ORF FUM12 CAL0004792 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.6727 ORF RIT1 CAL0004801 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.6729 ORF TIP120 CAL0004808 PMID: 14663094|CGD_REF: CAL0080633 homozygous diploid, systematic mutation set (homozygous insertion mutants generated with URA3-ARG4-URA3 (UAU1) cassette) null BWP17 viable C. albicans orf19.6729 ORF TIP120 CAL0004808 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.6729 ORF TIP120 CAL0004808 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.6729 ORF TIP120 CAL0004808 PMID: 22080453|CGD_REF: CAL0000143626 homozygous diploid, classical genetics null Other C. albicans viable C. albicans orf19.6729 ORF TIP120 CAL0004808 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.6729 ORF TIP120 CAL0004808 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.673 ORF CAL0001092 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.6730 ORF CAL0004820 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.6734 ORF TCC1 CAL0004828 PMID: 16998076|CGD_REF: CAL0116908 homozygous diploid, classical genetics null CAI-4 filamentous growth: increased YPD at pH 5; under alkaline conditions; on Spider medium C. albicans orf19.6734 ORF TCC1 CAL0004828 PMID: 16998076|CGD_REF: CAL0116908 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.6734 ORF TCC1 CAL0004828 PMID: 16998076|CGD_REF: CAL0116908 homozygous diploid, classical genetics null Not recorded virulence: decreased mouse intravenous infection C. albicans orf19.6736 ORF CAL0004833 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: decreased growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.6736 ORF CAL0004833 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: decreased rate liquid synthetic complete medium C. albicans orf19.6736 ORF CAL0004833 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.6737 ORF CAL0004836 PMID: 14663094|CGD_REF: CAL0080633 homozygous diploid, systematic mutation set (homozygous insertion mutants generated with URA3-ARG4-URA3 (UAU1) cassette) null BWP17 viable C. albicans orf19.6738 ORF VAN1 CAL0004838 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.6738 ORF VAN1 CAL0004838 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.6738 ORF VAN1 CAL0004838 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.6738 ORF VAN1 CAL0004838 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.6739 ORF CAL0004841 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.674 ORF CAL0001095 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.6740 ORF CAL0004852 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.6741 ORF CAL0004854 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.6741 ORF CAL0004854 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.6741 ORF CAL0004854 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.6741 ORF CAL0004854 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 invasive growth: decreased solid SLAD media C. albicans orf19.6741 ORF CAL0004854 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.6742 ORF CAL0004856 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.6744 ORF CAL0004859 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.6745 ORF TPI1 CAL0004861 PMID: 12773383|CGD_REF: CAL0087974 heterozygous diploid, classical genetics (haploinsufficient phenotype assay) unspecified CAI-4 filamentous growth: increased solid Spider medium transposon insertion proximal to, but not within, the ORF C. albicans orf19.6745 ORF TPI1 CAL0004861 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.6747 ORF CAL0004865 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.6749 ORF KRS1 CAL0004871 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.6751 ORF CAL0004884 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.6755 ORF DLD2 CAL0004891 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.6755 ORF DLD2 CAL0004891 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient YNB medium C. albicans orf19.6757 ORF GCY1 CAL0004896 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, competitive growth (haploinsufficient phenotype assay, barcode deletion set) null SC5314 resistance to chemicals: decreased ergosterol analogs (ECC69 and/or ECC1384) C. albicans orf19.6757 ORF GCY1 CAL0004896 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.6760 ORF MDS3 CAL0004914 PMID: 12524333|CGD_REF: CAL0080691 homozygous diploid, systematic mutation set (homozygous insertion mutants generated with URA3-ARG4-URA3 (UAU1) cassette) null BWP17 metal resistance: decreased lithium chloride slight growth defect in presence of LiCl C. albicans orf19.6760 ORF MDS3 CAL0004914 PMID: 12524333|CGD_REF: CAL0080691 homozygous diploid, systematic mutation set (homozygous insertion mutants generated with URA3-ARG4-URA3 (UAU1) cassette) null BWP17 viable C. albicans orf19.6760 ORF MDS3 CAL0004914 PMID: 14663094|CGD_REF: CAL0080633 homozygous diploid, systematic mutation set (homozygous insertion mutants generated with URA3-ARG4-URA3 (UAU1) cassette) null BWP17 viable C. albicans orf19.6760 ORF MDS3 CAL0004914 PMID: 12524333|CGD_REF: CAL0080691 homozygous diploid, systematic mutation set (homozygous insertion mutants generated with URA3-ARG4-URA3 (UAU1) cassette) null BWP17 alkaline pH resistance: decreased slight growth defect at pH 9 C. albicans orf19.6760 ORF MDS3 CAL0004914 PMID: 12524333|CGD_REF: CAL0080691 homozygous diploid, systematic mutation set (homozygous insertion mutants generated with URA3-ARG4-URA3 (UAU1) cassette) null BWP17 hyphal growth: abnormal defective alkaline pH-induced hyphal growth C. albicans orf19.6760 ORF MDS3 CAL0004914 PMID: 14663094|CGD_REF: CAL0080633 homozygous diploid, systematic mutation set (homozygous insertion mutants generated with URA3-ARG4-URA3 (UAU1) cassette) null BWP17 hyphal growth: decreased embedded in solid medium C. albicans orf19.6760 ORF MDS3 CAL0004914 PMID: 16087754|CGD_REF: CAL0114512 homozygous diploid, classical genetics null BWP17 hyphal growth: absent M199 pH 8 and Spider media C. albicans orf19.6760 ORF MDS3 CAL0004914 PMID: 14663094|CGD_REF: CAL0080633 homozygous diploid, systematic mutation set (homozygous insertion mutants generated with URA3-ARG4-URA3 (UAU1) cassette) null BWP17 chlamydospore formation: decreased C. albicans orf19.6760 ORF MDS3 CAL0004914 PMID: 16087754|CGD_REF: CAL0114512 homozygous diploid, classical genetics null BWP17 biofilm formation: decreased C. albicans orf19.6760 ORF MDS3 CAL0004914 PMID: 23856128|CGD_REF: CAL0000172540 homozygous diploid, classical genetics null BWP17 resistance to chemicals: decreased propolis C. albicans orf19.6760 ORF MDS3 CAL0004914 PMID: 16087754|CGD_REF: CAL0114512 homozygous diploid, classical genetics null mds3::Tn7-UAU1/mds3::Tn7-URA3 BWP17 biofilm formation: abnormal 60 h at 37 deg C in Spider medium or 60 h at 37 deg C in SD medium plus 50 mM glucose on silicone squares blocked at an early step of biofilm formation before the production of hyphae; mutants form a thin 10-um layer of cells, primarily yeast cells, though a few elongated cells representing pseudohyphae are occasionally seen C. albicans orf19.6760 ORF MDS3 CAL0004914 PMID: 16087754|CGD_REF: CAL0114512 homozygous diploid, classical genetics null mds3::Tn7-UAU1/mds3::Tn7-URA3 BWP17 germ tube formation: absent M199 medium, pH 8, at 37 deg C for 12 h -alkaline media completely defective in alkaline-induced hyphal morphogenesis C. albicans orf19.6760 ORF MDS3 CAL0004914 PMID: 12524333|CGD_REF: CAL0080691 homozygous diploid, systematic mutation set (homozygous insertion mutants generated with URA3-ARG4-URA3 (UAU1) cassette) null BWP17 virulence: decreased mouse intravenous infection C. albicans orf19.6760 ORF MDS3 CAL0004914 PMID: 16939537|CGD_REF: CAL0117180 homozygous diploid, classical genetics null Not recorded virulence: decreased endothelial cells decreased capacity to damage cells in vitro model of infection C. albicans orf19.6760 ORF MDS3 CAL0004914 PMID: 17241762|CGD_REF: CAL0117323 homozygous diploid, classical genetics null Not recorded virulence: decreased mild defect mouse corneal infection C. albicans orf19.6760 ORF MDS3 CAL0004914 PMID: 20457806|CGD_REF: CAL0125442 homozygous diploid, classical genetics null Other C. albicans hyphal growth: decreased liquid M199 pH 8 medium at 37 deg C hyphal growth defect is severe and is partially rescued by treatment with 5 nM rapamycin C. albicans orf19.6760 ORF MDS3 CAL0004914 PMID: 20457806|CGD_REF: CAL0125442 homozygous diploid, classical genetics null Other C. albicans alkaline pH resistance: decreased YPD medium, pH 9 C. albicans orf19.6760 ORF MDS3 CAL0004914 PMID: 20457806|CGD_REF: CAL0125442 homozygous diploid, classical genetics null Other C. albicans resistance to chemicals: increased rapamycin (5 nM) Spider medium mutant displays resistance on nutrient poor medium but not on rich medium C. albicans orf19.6763 ORF SLK19 CAL0004917 PMID: 15289560|CGD_REF: CAL0082072 homozygous diploid, classical genetics null Not recorded flocculation: increased C. albicans orf19.6763 ORF SLK19 CAL0004917 PMID: 15289560|CGD_REF: CAL0082072 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased Calcofluor White solid Lee's medium at alkaline pH C. albicans orf19.6763 ORF SLK19 CAL0004917 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.6763 ORF SLK19 CAL0004917 PMID: 14663094|CGD_REF: CAL0080633 homozygous diploid, systematic mutation set (homozygous insertion mutants generated with URA3-ARG4-URA3 (UAU1) cassette) null BWP17 viable C. albicans orf19.6763 ORF SLK19 CAL0004917 PMID: 15289560|CGD_REF: CAL0082072 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.6763 ORF SLK19 CAL0004917 PMID: 15289560|CGD_REF: CAL0082072 homozygous diploid, classical genetics null Not recorded cell wall morphology: abnormal increased cell surface hydrophobicity C. albicans orf19.6763 ORF SLK19 CAL0004917 PMID: 15289560|CGD_REF: CAL0082072 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased Congo Red solid Lee's medium at alkaline pH C. albicans orf19.6763 ORF SLK19 CAL0004917 PMID: 15289560|CGD_REF: CAL0082072 homozygous diploid, classical genetics null Not recorded virulence: decreased mouse intravenous infection C. albicans orf19.6766 ORF NOP13 CAL0004922 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.677 ORF CHO1 CAL0001102 PMID: 12773383|CGD_REF: CAL0087974 heterozygous diploid, classical genetics (haploinsufficient phenotype assay) unspecified CAI-4 filamentous growth: decreased solid Spider medium or solid YEPD plus serum transposon insertion proximal to, but not within, the ORF C. albicans orf19.677 ORF CHO1 CAL0001102 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.677 ORF CHO1 CAL0001102 PMID: 20132453|CGD_REF: CAL0125003 homozygous diploid, classical genetics null SC5314 viable C. albicans orf19.677 ORF CHO1 CAL0001102 PMID: 20132453|CGD_REF: CAL0125003 homozygous diploid, classical genetics null cho1/cho1-CaNAT1-FLP SC5314 auxotrophy ethanolamine (1 mM) C. albicans orf19.677 ORF CHO1 CAL0001102 PMID: 20132453|CGD_REF: CAL0125003 homozygous diploid, classical genetics null SC5314 filamentous growth: increased filamentous growth greater than wild-type on solid Spider plus 1mM ethanolamine with 1 mM sorbitol or YPD plus 10% serum with 1 mM sorbitol C. albicans orf19.677 ORF CHO1 CAL0001102 PMID: 20132453|CGD_REF: CAL0125003 homozygous diploid, classical genetics null cho1/cho1-CaNAT1-FLP SC5314 resistance to chemicals: increased caspofungin (25 micrograms/ml) C. albicans orf19.677 ORF CHO1 CAL0001102 PMID: 20132453|CGD_REF: CAL0125003 homozygous diploid, classical genetics null cho1/cho1-CaNAT1-FLP SC5314 resistance to chemicals: increased paraquat C. albicans orf19.677 ORF CHO1 CAL0001102 PMID: 20132453|CGD_REF: CAL0125003 homozygous diploid, classical genetics null cho1/cho1-CaNAT1-FLP SC5314 cold sensitivity: increased 37, 30 15 degrees C C. albicans orf19.677 ORF CHO1 CAL0001102 PMID: 20132453|CGD_REF: CAL0125003 homozygous diploid, classical genetics null cho1/cho1-CaNAT1-FLP SC5314 virulence: decreased mouse intravenous infection C. albicans orf19.677 ORF CHO1 CAL0001102 PMID: 20132453|CGD_REF: CAL0125003 homozygous diploid, classical genetics null cho1/cho1-CaNAT1-FLP SC5314 respiratory metabolism: decreased trypan blue and eosin Y indicator plates used to detect mitochondrial dysfunction; dyes taken up more readily by mutants C. albicans orf19.677 ORF CHO1 CAL0001102 PMID: 20132453|CGD_REF: CAL0125003 homozygous diploid, classical genetics null cho1/cho1-CaNAT1-FLP SC5314 filamentous growth: decreased Spider medium plus 1 mM ethanolamine, 68 h C. albicans orf19.6771 ORF UBI4 CAL0004945 PMID: 12742065|CGD_REF: CAL0081530 heterozygous diploid, classical genetics repressible CAI-4 filamentous growth: abnormal induction of hyphal and pseudohyphal growth C. albicans orf19.6771 ORF UBI4 CAL0004945 PMID: 12742065|CGD_REF: CAL0081530 heterozygous diploid, classical genetics repressible CAI-4 heat sensitivity: increased sensitive to chronic heat stress, but not heat shock, at stationary phase on glycerol C. albicans orf19.6771 ORF UBI4 CAL0004945 PMID: 12742065|CGD_REF: CAL0081530 heterozygous diploid, classical genetics repressible CAI-4 viable wild-type growth rate C. albicans orf19.6771 ORF UBI4 CAL0004945 PMID: 12742065|CGD_REF: CAL0081530 heterozygous diploid, classical genetics null Not recorded viable C. albicans orf19.6771 ORF UBI4 CAL0004945 PMID: 12742065|CGD_REF: CAL0081530 homozygous diploid, classical genetics null Not recorded inviable homozygous null mutant strain could not be recovered, suggesting that the gene is essential under the selection conditions C. albicans orf19.6771 ORF UBI4 CAL0004945 PMID: 12742065|CGD_REF: CAL0081530 heterozygous diploid, classical genetics repressible CAI-4 phenotypic switching: increased increased frequency of phenotypic switching C. albicans orf19.6771 ORF UBI4 CAL0004945 PMID: 21269335|CGD_REF: CAL0141401 homozygous diploid, classical genetics null ubi4::URA3/ubi4::ARG4 BWP17 viable C. albicans orf19.6771 ORF UBI4 CAL0004945 PMID: 21269335|CGD_REF: CAL0141401 homozygous diploid, classical genetics null ubi4::URA3/ubi4::ARG4 BWP17 colony appearance: abnormal solid YPD medium wrinkled, rough, asymmetrical colonies C. albicans orf19.6771 ORF UBI4 CAL0004945 PMID: 21269335|CGD_REF: CAL0141401 homozygous diploid, classical genetics null ubi4::URA3/ubi4::ARG4 BWP17 liquid culture appearance: abnormal liquid YPD medium mixture of yeast, pseudohyphal and hyphal cells C. albicans orf19.6771 ORF UBI4 CAL0004945 PMID: 21269335|CGD_REF: CAL0141401 homozygous diploid, classical genetics null ubi4::URA3/ubi4::ARG4 BWP17 nuclear position: abnormal liquid YPD medium defective nuclear segregation C. albicans orf19.6771 ORF UBI4 CAL0004945 PMID: 21269335|CGD_REF: CAL0141401 homozygous diploid, classical genetics null ubi4::URA3/ubi4::ARG4 BWP17 nuclear position: abnormal liquid YPD medium with 10% serum (hypha-inducing) defective nuclear segregation C. albicans orf19.6771 ORF UBI4 CAL0004945 PMID: 21269335|CGD_REF: CAL0141401 homozygous diploid, classical genetics null ubi4::URA3/ubi4::ARG4 BWP17 heat sensitivity: increased elevated temperatures (37 or 42 deg) C. albicans orf19.6771 ORF UBI4 CAL0004945 PMID: 21269335|CGD_REF: CAL0141401 homozygous diploid, classical genetics null ubi4::URA3/ubi4::ARG4 BWP17 oxidative stress resistance: decreased hydrogen peroxide C. albicans orf19.6771 ORF UBI4 CAL0004945 PMID: 21269335|CGD_REF: CAL0141401 homozygous diploid, classical genetics null ubi4::URA3/ubi4::ARG4 BWP17 resistance to chemicals: decreased Congo Red C. albicans orf19.6771 ORF UBI4 CAL0004945 PMID: 21269335|CGD_REF: CAL0141401 homozygous diploid, classical genetics null ubi4::URA3/ubi4::ARG4 BWP17 resistance to chemicals: decreased caspofungin C. albicans orf19.6771 ORF UBI4 CAL0004945 PMID: 21269335|CGD_REF: CAL0141401 homozygous diploid, classical genetics null ubi4::URA3/ubi4::ARG4 BWP17 resistance to chemicals: decreased Calcofluor White C. albicans orf19.6771 ORF UBI4 CAL0004945 PMID: 21269335|CGD_REF: CAL0141401 homozygous diploid, classical genetics null ubi4::URA3/ubi4::ARG4 BWP17 resistance to chemicals: decreased tunicamycin C. albicans orf19.6771 ORF UBI4 CAL0004945 PMID: 21269335|CGD_REF: CAL0141401 homozygous diploid, classical genetics null ubi4::URA3/ubi4::ARG4 BWP17 starvation resistance: decreased C. albicans orf19.6771 ORF UBI4 CAL0004945 PMID: 21269335|CGD_REF: CAL0141401 homozygous diploid, classical genetics null ubi4/ubi4 BWP17 virulence: decreased mouse intravenous infection C. albicans orf19.6773 ORF ECM29 CAL0004949 PMID: 12773383|CGD_REF: CAL0087974 heterozygous diploid, classical genetics (haploinsufficient phenotype assay) null CAI-4 filamentous growth: decreased solid Spider medium heterozygous transposon insertion C. albicans orf19.6773 ORF ECM29 CAL0004949 PMID: 12773383|CGD_REF: CAL0087974 heterozygous diploid, classical genetics (haploinsufficient phenotype assay) null CAI-4 viable heterozygous transposon insertion C. albicans orf19.6773 ORF ECM29 CAL0004949 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.6776 ORF GCD2 CAL0004955 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.6778 ORF CAL0004962 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.6779 ORF PRO2 CAL0004966 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.6781 ORF ZFU2 CAL0004980 PMID: 15964282|CGD_REF: CAL0114274 homozygous diploid, systematic mutation set (split-marker transposon insertion strategy to disrupt both alleles) null BWP17 viable C. albicans orf19.6781 ORF ZFU2 CAL0004980 PMID: 15964282|CGD_REF: CAL0114274 homozygous diploid, systematic mutation set (split-marker transposon insertion strategy to disrupt both alleles) null BWP17 biofilm formation: normal C. albicans orf19.6781 ORF ZFU2 CAL0004980 PMID: 22073120|CGD_REF: CAL0000143592 homozygous diploid, classical genetics null BWP17 viable C. albicans orf19.6781 ORF ZFU2 CAL0004980 PMID: 22073120|CGD_REF: CAL0000143592 homozygous diploid, classical genetics null BWP17 colony appearance: abnormal increased colony wrinkling C. albicans orf19.6781 ORF ZFU2 CAL0004980 PMID: 22581526|CGD_REF: CAL0000157314 homozygous diploid, systematic mutation set null BWP17 resistance to chemicals: decreased caspofungin C. albicans orf19.6781 ORF ZFU2 CAL0004980 PMID: 22359502|CGD_REF: CAL0000144048 homozygous diploid, classical genetics null BWP17 viable insertion mutant, independent BWP17 and SN152 deletion mutants also tested C. albicans orf19.6781 ORF ZFU2 CAL0004980 PMID: 22359502|CGD_REF: CAL0000144048 homozygous diploid, classical genetics null BWP17 adhesion: decreased insertion mutant, independent BWP17 and SN152 deletion mutants also tested C. albicans orf19.6781 ORF ZFU2 CAL0004980 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 invasive growth: decreased solid SLAD media C. albicans orf19.6782 ORF BMT1 CAL0004981 PMID: 18234669|CGD_REF: CAL0119018 homozygous diploid, classical genetics null Not recorded resistance to chemicals: normal Calcofluor White C. albicans orf19.6782 ORF BMT1 CAL0004981 PMID: 18234669|CGD_REF: CAL0119018 homozygous diploid, classical genetics null Not recorded viable rich medium wild-type growth rate C. albicans orf19.6782 ORF BMT1 CAL0004981 PMID: 18234669|CGD_REF: CAL0119018 homozygous diploid, classical genetics null Not recorded resistance to chemicals: normal sodium dodecyl sulfate C. albicans orf19.6782 ORF BMT1 CAL0004981 PMID: 18234669|CGD_REF: CAL0119018 homozygous diploid, classical genetics null BWP17 hyphal growth: normal serum-containing medium C. albicans orf19.6782 ORF BMT1 CAL0004981 PMID: 18234669|CGD_REF: CAL0119018 homozygous diploid, classical genetics null Not recorded cell wall morphology: abnormal strongly decreased beta-mannosylation of both acid-stable and acid-labile fractions of phosphopeptidomannan C. albicans orf19.6782 ORF BMT1 CAL0004981 PMID: 18234669|CGD_REF: CAL0119018 homozygous diploid, classical genetics null Not recorded chlamydospore formation: normal RAT medium C. albicans orf19.6782 ORF BMT1 CAL0004981 PMID: 18234669|CGD_REF: CAL0119018 homozygous diploid, classical genetics null Not recorded ionic stress resistance: normal sodium chloride C. albicans orf19.6782 ORF BMT1 CAL0004981 PMID: 18234669|CGD_REF: CAL0119018 homozygous diploid, classical genetics null Not recorded resistance to chemicals: normal calcium dichloride C. albicans orf19.6783 ORF CAL0004982 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.6784 ORF PGA32 CAL0004984 PMID: 18765290|CGD_REF: CAL0119430 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.6784 ORF PGA32 CAL0004984 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: decreased growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.6784 ORF PGA32 CAL0004984 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.6784 ORF PGA32 CAL0004984 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.6784 ORF PGA32 CAL0004984 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.6787 ORF CAL0004990 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.679 ORF FGR39 CAL0001107 PMID: 12773383|CGD_REF: CAL0087974 heterozygous diploid, classical genetics (haploinsufficient phenotype assay) unspecified CAI-4 filamentous growth: decreased solid Spider medium or solid YEPD plus serum transposon insertion proximal to, but not within, the ORF C. albicans orf19.6790 ORF CAL0004999 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.6792 ORF RRD1 CAL0005001 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.6793 ORF CAL0005002 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 invasive growth: decreased solid SLAD media C. albicans orf19.6794 ORF FESUR1 CAL0005004 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.6798 ORF SSN6 CAL0005010 PMID: 12581357|CGD_REF: CAL0081069 homozygous diploid, classical genetics null CAI-4 filamentous growth: abnormal mutant forms pseudohyphae with abnormal stubby morphology under conditions where wild type grows in yeast form or true hyphal form C. albicans orf19.6798 ORF SSN6 CAL0005010 PMID: 12581357|CGD_REF: CAL0081069 heterozygous diploid, classical genetics overexpression CAI-4 filamentous growth: increased liquid SCAA medium, 28 deg C; various solid media C. albicans orf19.6798 ORF SSN6 CAL0005010 PMID: 12581357|CGD_REF: CAL0081069 homozygous diploid, classical genetics null Not recorded respiratory growth: decreased slow growth utilizing nonfermentable carbon sources acetate or lactate C. albicans orf19.6798 ORF SSN6 CAL0005010 PMID: 20041210|CGD_REF: CAL0124764 homozygous diploid, systematic mutation set null SN152 resistance to chemicals: increased flucytosine strongly resistant C. albicans orf19.6798 ORF SSN6 CAL0005010 PMID: 12581357|CGD_REF: CAL0081069 homozygous diploid, classical genetics null Not recorded heat sensitivity: increased 43 deg C C. albicans orf19.6798 ORF SSN6 CAL0005010 PMID: 20041210|CGD_REF: CAL0124764 homozygous diploid, systematic mutation set null SN152 vegetative growth: decreased MM or Lee's pH 4.5 media at 30 deg C strongly decreased C. albicans orf19.6798 ORF SSN6 CAL0005010 PMID: 12581357|CGD_REF: CAL0081069 heterozygous diploid, classical genetics overexpression CAI-4 viable C. albicans orf19.6798 ORF SSN6 CAL0005010 PMID: 12581357|CGD_REF: CAL0081069 heterozygous diploid, classical genetics null Not recorded viable C. albicans orf19.6798 ORF SSN6 CAL0005010 PMID: 12581357|CGD_REF: CAL0081069 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.6798 ORF SSN6 CAL0005010 PMID: 15814841|CGD_REF: CAL0114185 heterozygous diploid, classical genetics null Not recorded viable C. albicans orf19.6798 ORF SSN6 CAL0005010 PMID: 15814841|CGD_REF: CAL0114185 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.6798 ORF SSN6 CAL0005010 PMID: 20041210|CGD_REF: CAL0124764 homozygous diploid, systematic mutation set null SN152 invasive growth: increased SD medium at 30 deg C strongly increased C. albicans orf19.6798 ORF SSN6 CAL0005010 PMID: 12581357|CGD_REF: CAL0081069 homozygous diploid, classical genetics null Not recorded oxidative stress resistance: increased hydrogen peroxide C. albicans orf19.6798 ORF SSN6 CAL0005010 PMID: 15814841|CGD_REF: CAL0114185 homozygous diploid, classical genetics null Not recorded cell shape: abnormal cells are pseudohyphal-like (but not truly pseudohyphal) or stumpy C. albicans orf19.6798 ORF SSN6 CAL0005010 PMID: 20041210|CGD_REF: CAL0124764 homozygous diploid, systematic mutation set null SN152 colony appearance: abnormal Spider medium enhanced colony wrinkling C. albicans orf19.6798 ORF SSN6 CAL0005010 PMID: 20041210|CGD_REF: CAL0124764 homozygous diploid, systematic mutation set null SN152 colony color: abnormal CHROMagar medium at 30 and 37 deg C darker than normal C. albicans orf19.6798 ORF SSN6 CAL0005010 PMID: 12581357|CGD_REF: CAL0081069 homozygous diploid, classical genetics null Not recorded oxidative stress resistance: increased C. albicans orf19.6798 ORF SSN6 CAL0005010 PMID: 12581357|CGD_REF: CAL0081069 heterozygous diploid, classical genetics overexpression CAI-4 virulence: decreased mouse intravenous infection C. albicans orf19.6798 ORF SSN6 CAL0005010 PMID: 12581357|CGD_REF: CAL0081069 homozygous diploid, classical genetics null Not recorded virulence: decreased mouse intravenous infection C. albicans orf19.6798 ORF SSN6 CAL0005010 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient YPD medium C. albicans orf19.680 ORF TIM50 CAL0001128 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.680 ORF TIM50 CAL0001128 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 invasive growth: decreased solid SLAD media C. albicans orf19.680 ORF TIM50 CAL0001128 PMID: 21135205|CGD_REF: CAL0139967 heterozygous diploid, large-scale survey (large-scale identification of genes essential for virulence in mouse) repressible CAI-4 virulence: absent mouse intravenous infection C. albicans orf19.6800 ORF POS5 CAL0005607 PMID: 12524333|CGD_REF: CAL0080691 homozygous diploid, systematic mutation set (homozygous insertion mutants generated with URA3-ARG4-URA3 (UAU1) cassette) null BWP17 inviable homozygous null mutant strain could not be recovered, suggesting that the gene is essential under the selection conditions C. albicans orf19.6800 ORF POS5 CAL0005607 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient YPD medium C. albicans orf19.6800 ORF POS5 CAL0005607 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient SC medium C. albicans orf19.6800 ORF POS5 CAL0005607 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient SLAD medium C. albicans orf19.6801 ORF RPD31 CAL0005608 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.6801 ORF RPD31 CAL0005608 PMID: 19555456|CGD_REF: CAL0123821 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.6801 ORF RPD31 CAL0005608 PMID: 19555456|CGD_REF: CAL0123821 homozygous diploid, classical genetics null Not recorded phenotypic switching: increased MTLa/MTLa background white-to-opaque switching C. albicans orf19.6802 ORF CAL0005610 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.6802 ORF CAL0005610 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.6802 ORF CAL0005610 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.6802 ORF CAL0005610 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.6802 ORF CAL0005610 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.6804 ORF CAL0005615 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.6804 ORF CAL0005615 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient SLAD medium C. albicans orf19.6805 ORF CAL0005617 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient YPD medium C. albicans orf19.6805 ORF CAL0005617 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient SC medium C. albicans orf19.6805 ORF CAL0005617 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient YNB medium C. albicans orf19.6809 ORF CAL0005628 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.681 ORF HAP43 CAL0001129 PMID: 18503007|CGD_REF: CAL0119016 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased iron chelators C. albicans orf19.681 ORF HAP43 CAL0001129 PMID: 20041210|CGD_REF: CAL0124764 homozygous diploid, systematic mutation set null SN152 resistance to chemicals: decreased BPS (150 uM bathophenanthrolinedisulfonic?acid, an iron chelator) strongly sensitive C. albicans orf19.681 ORF HAP43 CAL0001129 PMID: 18503007|CGD_REF: CAL0119016 homozygous diploid, classical genetics null Not recorded vegetative growth: normal rate solid YPG medium C. albicans orf19.681 ORF HAP43 CAL0001129 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.681 ORF HAP43 CAL0001129 PMID: 18503007|CGD_REF: CAL0119016 heterozygous diploid, classical genetics null Not recorded viable C. albicans orf19.681 ORF HAP43 CAL0001129 PMID: 18503007|CGD_REF: CAL0119016 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.681 ORF HAP43 CAL0001129 PMID: 20041210|CGD_REF: CAL0124764 homozygous diploid, systematic mutation set null SN152 alkaline pH resistance: decreased pH 10.5 strongly sensitive C. albicans orf19.681 ORF HAP43 CAL0001129 PMID: 20041210|CGD_REF: CAL0124764 homozygous diploid, systematic mutation set null SN152 metal resistance: increased copper(2+) strongly resistant C. albicans orf19.681 ORF HAP43 CAL0001129 PMID: 21592964|CGD_REF: CAL0142015 homozygous diploid, classical genetics null SN152 virulence: delayed decreased fungal burdens in the brains and kineys of infected mice mouse intravenous infection C. albicans orf19.681 ORF HAP43 CAL0001129 PMID: 21592964|CGD_REF: CAL0142015 homozygous diploid, classical genetics null SN152 RNA accumulation: increased SFU1 mRNA C. albicans orf19.681 ORF HAP43 CAL0001129 PMID: 21131439|CGD_REF: CAL0139970 homozygous diploid, classical genetics null SC5314 utilization of iron source: decreased unable to grow in iron-limiting conditions C. albicans orf19.681 ORF HAP43 CAL0001129 PMID: 21131439|CGD_REF: CAL0139970 homozygous diploid, classical genetics null SC5314 virulence: decreased mouse intravenous infection C. albicans orf19.6810 ORF CAL0005649 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.6810 ORF CAL0005649 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient YNB medium C. albicans orf19.6812 ORF PMT2 CAL0005653 PMID: 15659169|CGD_REF: CAL0082300 heterozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased ketoconazole C. albicans orf19.6812 ORF PMT2 CAL0005653 PMID: 15659169|CGD_REF: CAL0082300 heterozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased Hygromycin B C. albicans orf19.6812 ORF PMT2 CAL0005653 PMID: 15659169|CGD_REF: CAL0082300 heterozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased G418 C. albicans orf19.6812 ORF PMT2 CAL0005653 PMID: 15659169|CGD_REF: CAL0082300 heterozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased Calcofluor White C. albicans orf19.6812 ORF PMT2 CAL0005653 PMID: 15659169|CGD_REF: CAL0082300 heterozygous diploid, classical genetics null Not recorded heat sensitivity: increased C. albicans orf19.6812 ORF PMT2 CAL0005653 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.6812 ORF PMT2 CAL0005653 PMID: 15659169|CGD_REF: CAL0082300 heterozygous diploid, classical genetics null Not recorded viable C. albicans orf19.6812 ORF PMT2 CAL0005653 PMID: 15659169|CGD_REF: CAL0082300 heterozygous diploid, classical genetics null CAI-4 hyphal growth: absent Lee's or Spider media C. albicans orf19.6812 ORF PMT2 CAL0005653 PMID: 15659169|CGD_REF: CAL0082300 heterozygous diploid, classical genetics null CAI-4 hyphal growth: normal oxygen-limited conditions C. albicans orf19.6812 ORF PMT2 CAL0005653 PMID: 15659169|CGD_REF: CAL0082300 homozygous diploid, classical genetics null Not recorded inviable C. albicans orf19.6812 ORF PMT2 CAL0005653 PMID: 15659169|CGD_REF: CAL0082300 heterozygous diploid, classical genetics null Not recorded cold sensitivity: increased C. albicans orf19.6812 ORF PMT2 CAL0005653 PMID: 15659169|CGD_REF: CAL0082300 heterozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased Congo Red C. albicans orf19.6812 ORF PMT2 CAL0005653 PMID: 17885949|CGD_REF: CAL0118767 heterozygous diploid, classical genetics null CAI-4 protein activity: decreased extracellular protease C. albicans orf19.6812 ORF PMT2 CAL0005653 PMID: 17885949|CGD_REF: CAL0118767 heterozygous diploid, classical genetics null CAI-4 protein activity: decreased phospholipase C. albicans orf19.6812 ORF PMT2 CAL0005653 PMID: 17885949|CGD_REF: CAL0118767 heterozygous diploid, classical genetics null CAI-4 induction of host response: increased murine peritoneal macrophages mutant cells induce a greater amount of IL-12p70 C. albicans orf19.6812 ORF PMT2 CAL0005653 PMID: 21407800|CGD_REF: CAL0141800 heterozygous diploid, competitive growth null BWP17 interaction with host/environment: abnormal significantly reduced invasion and damage to epithelial cells, but normal adhesion ex vivo model of infection C. albicans orf19.6812 ORF PMT2 CAL0005653 PMID: 17885949|CGD_REF: CAL0118767 heterozygous diploid, classical genetics null CAI-4 resistance to killing by host cells: increased in vitro model of infection (thioglycollate induced macrophages) C. albicans orf19.6812 ORF PMT2 CAL0005653 PMID: 17005840|CGD_REF: CAL0116746 homozygous diploid, classical genetics null CAF2-1 biofilm formation: decreased C. albicans orf19.6814 ORF TDH3 CAL0005657 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 invasive growth: decreased solid SLAD media C. albicans orf19.6816 ORF CAL0005659 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.6817 ORF FCR1 CAL0005662 PMID: 9864335|CGD_REF: CAL0081289 homozygous diploid, classical genetics null Not recorded resistance to chemicals: increased brefeldin A C. albicans orf19.6817 ORF FCR1 CAL0005662 PMID: 9864335|CGD_REF: CAL0081289 homozygous diploid, classical genetics null Not recorded resistance to chemicals: increased ketoconazole C. albicans orf19.6817 ORF FCR1 CAL0005662 PMID: 12773383|CGD_REF: CAL0087974 heterozygous diploid, classical genetics (haploinsufficient phenotype assay) unspecified CAI-4 filamentous growth: increased solid YEPD plus serum transposon insertion proximal to, but not within, the ORF C. albicans orf19.6817 ORF FCR1 CAL0005662 PMID: 15964282|CGD_REF: CAL0114274 homozygous diploid, systematic mutation set (split-marker transposon insertion strategy to disrupt both alleles) null BWP17 viable C. albicans orf19.6817 ORF FCR1 CAL0005662 PMID: 19463063|CGD_REF: CAL0123630 homozygous diploid, systematic mutation set (split-marker transposon insertion strategy to disrupt both alleles) null BWP17 viable C. albicans orf19.6817 ORF FCR1 CAL0005662 PMID: 9864335|CGD_REF: CAL0081289 homozygous diploid, classical genetics null Not recorded viable wild-type growth rate C. albicans orf19.6817 ORF FCR1 CAL0005662 PMID: 15964282|CGD_REF: CAL0114274 homozygous diploid, systematic mutation set (split-marker transposon insertion strategy to disrupt both alleles) null BWP17 biofilm formation: normal C. albicans orf19.6817 ORF FCR1 CAL0005662 PMID: 9864335|CGD_REF: CAL0081289 homozygous diploid, classical genetics null Not recorded resistance to chemicals: increased fluconazole C. albicans orf19.6817 ORF FCR1 CAL0005662 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.6817 ORF FCR1 CAL0005662 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.6817 ORF FCR1 CAL0005662 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.6817 ORF FCR1 CAL0005662 PMID: 19463063|CGD_REF: CAL0123630 homozygous diploid, systematic mutation set (split-marker transposon insertion strategy to disrupt both alleles) null BWP17 virulence: normal Toll mutant D. melanogaster invasive infection insect infection C. albicans orf19.6817 ORF FCR1 CAL0005662 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.6818 ORF CAL0005664 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.6820 ORF CAL0005688 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.6821 ORF CAL0005690 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.6824 ORF TRY6 CAL0005695 PMID: 22359502|CGD_REF: CAL0000144048 homozygous diploid, classical genetics null BWP17 viable insertion mutant, independent SN152 deletion mutant strain also tested C. albicans orf19.6824 ORF TRY6 CAL0005695 PMID: 22359502|CGD_REF: CAL0000144048 homozygous diploid, classical genetics null BWP17 adhesion: decreased insertion mutant, independent SN152 deletion mutant strain also tested C. albicans orf19.6824 ORF TRY6 CAL0005695 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 invasive growth: decreased solid SLAD media C. albicans orf19.6827 ORF SLU7 CAL0005702 PMID: 21135205|CGD_REF: CAL0139967 heterozygous diploid, large-scale survey (large-scale identification of genes essential for virulence in mouse) repressible CAI-4 virulence: absent mouse intravenous infection C. albicans orf19.6828 ORF CAL0005705 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.6828.1 ORF CAF0007087 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.6828.1 ORF CAF0007087 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 invasive growth: decreased solid SLAD media C. albicans orf19.6830 ORF CAL0005723 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.6832 ORF CAL0005727 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.6834.10 ORF TAR1 CAF0007114 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient SLAD medium C. albicans orf19.6838 ORF CAL0005741 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.6838 ORF CAL0005741 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.6838 ORF CAL0005741 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.6838 ORF CAL0005741 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.6838 ORF CAL0005741 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.684 ORF CAL0001134 PMID: 19623926|CGD_REF: CAL0124054 heterozygous diploid, competitive growth (haploinsufficient phenotype assay, barcode deletion set) null SC5314 resistance to chemicals: decreased parnafungin C. albicans orf19.684 ORF CAL0001134 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.684 ORF CAL0001134 PMID: 15964282|CGD_REF: CAL0114274 homozygous diploid, systematic mutation set (split-marker transposon insertion strategy to disrupt both alleles) null BWP17 inviable homozygous null mutant strain could not be recovered, suggesting that the gene is essential under the selection conditions C. albicans orf19.684 ORF CAL0001134 PMID: 19623926|CGD_REF: CAL0124054 heterozygous diploid, competitive growth (haploinsufficient phenotype assay, barcode deletion set) null SC5314 resistance to chemicals: decreased cordycepin C. albicans orf19.6842 ORF TUS1 CAL0005760 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.6842 ORF TUS1 CAL0005760 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: decreased growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.6842 ORF TUS1 CAL0005760 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: abnormal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.6842 ORF TUS1 CAL0005760 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.6842 ORF TUS1 CAL0005760 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.6843 ORF CAL0005761 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.6843 ORF CAL0005761 PMID: 23075292|CGD_REF: CAL0000158032 homozygous diploid, classical genetics null SC5314 viable C. albicans orf19.6843 ORF CAL0005761 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 invasive growth: decreased solid SLAD media C. albicans orf19.6844 ORF ICL1 CAL0005762 PMID: 11452311|CGD_REF: CAL0081441 homozygous diploid, classical genetics null Not recorded filamentous growth: normal solid serum-containing medium or neutral pH C. albicans orf19.6844 ORF ICL1 CAL0005762 PMID: 11452311|CGD_REF: CAL0081441 homozygous diploid, classical genetics null Not recorded germ tube formation: normal liquid serum-containing or neutral pH media C. albicans orf19.6844 ORF ICL1 CAL0005762 PMID: 11452311|CGD_REF: CAL0081441 homozygous diploid, classical genetics null Not recorded stress resistance: normal C. albicans orf19.6844 ORF ICL1 CAL0005762 PMID: 16963628|CGD_REF: CAL0116907 homozygous diploid, classical genetics null Not recorded utilization of carbon source: decreased nonfermentable carbon sources severe decrease C. albicans orf19.6844 ORF ICL1 CAL0005762 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.6844 ORF ICL1 CAL0005762 PMID: 14507372|CGD_REF: CAL0088818 heterozygous diploid, large-scale survey (large-scale identification of essential genes by gene replacement and conditional expression (GRACE) method) repressible CAI-4 viable one allele is deleted and the other is placed under repressible Tet promoter C. albicans orf19.6844 ORF ICL1 CAL0005762 PMID: 11452311|CGD_REF: CAL0081441 homozygous diploid, classical genetics null Not recorded viable YPD medium wild-type growth rate C. albicans orf19.6844 ORF ICL1 CAL0005762 PMID: 11452311|CGD_REF: CAL0081441 heterozygous diploid, classical genetics null Not recorded viable C. albicans orf19.6844 ORF ICL1 CAL0005762 PMID: 11452311|CGD_REF: CAL0081441 homozygous diploid, classical genetics null Not recorded utilization of carbon source: absent acetic acid C. albicans orf19.6844 ORF ICL1 CAL0005762 PMID: 11452311|CGD_REF: CAL0081441 homozygous diploid, classical genetics null Not recorded utilization of carbon source: absent oleic acid C. albicans orf19.6844 ORF ICL1 CAL0005762 PMID: 17158734|CGD_REF: CAL0117267 homozygous diploid, classical genetics null Not recorded utilization of carbon source: absent oleic acid C. albicans orf19.6844 ORF ICL1 CAL0005762 PMID: 11452311|CGD_REF: CAL0081441 homozygous diploid, classical genetics null Not recorded utilization of carbon source: absent ethanol C. albicans orf19.6844 ORF ICL1 CAL0005762 PMID: 17158734|CGD_REF: CAL0117267 homozygous diploid, classical genetics null Not recorded utilization of carbon source: absent ethanol C. albicans orf19.6844 ORF ICL1 CAL0005762 PMID: 17158734|CGD_REF: CAL0117267 homozygous diploid, classical genetics null Not recorded utilization of carbon source: absent glycerol C. albicans orf19.6844 ORF ICL1 CAL0005762 PMID: 17158734|CGD_REF: CAL0117267 homozygous diploid, classical genetics null Not recorded utilization of carbon source: absent citric acid C. albicans orf19.6844 ORF ICL1 CAL0005762 PMID: 21407800|CGD_REF: CAL0141800 homozygous diploid, classical genetics null CAI-4 interaction with host/environment: abnormal significantly reduced invasion and damage to epithelial cells, but normal adhesion ex vivo model of infection C. albicans orf19.6844 ORF ICL1 CAL0005762 PMID: 23285201|CGD_REF: CAL0000158306 homozygous diploid, classical genetics null BWP17 resistance to killing by host cells: decreased C. albicans orf19.6844 ORF ICL1 CAL0005762 PMID: 17158734|CGD_REF: CAL0117267 homozygous diploid, classical genetics null Not recorded virulence: decreased slight decrease mouse intravenous infection C. albicans orf19.6844 ORF ICL1 CAL0005762 PMID: 11452311|CGD_REF: CAL0081441 heterozygous diploid, classical genetics null Not recorded virulence: decreased mouse intravenous infection C. albicans orf19.6844 ORF ICL1 CAL0005762 PMID: 11452311|CGD_REF: CAL0081441 homozygous diploid, classical genetics null Not recorded virulence: decreased mouse intravenous infection C. albicans orf19.6844 ORF ICL1 CAL0005762 PMID: 16681837|CGD_REF: CAL0116091 homozygous diploid, classical genetics null Not recorded virulence: decreased mouse intravenous infection C. albicans orf19.6844 ORF ICL1 CAL0005762 PMID: 16963628|CGD_REF: CAL0116907 homozygous diploid, classical genetics null Not recorded virulence: decreased BALB/c mice mouse intravenous infection C. albicans orf19.6845 ORF CAL0005765 PMID: 15964282|CGD_REF: CAL0114274 homozygous diploid, systematic mutation set (split-marker transposon insertion strategy to disrupt both alleles) null BWP17 viable C. albicans orf19.6845 ORF CAL0005765 PMID: 15964282|CGD_REF: CAL0114274 homozygous diploid, systematic mutation set (split-marker transposon insertion strategy to disrupt both alleles) null BWP17 biofilm formation: normal C. albicans orf19.6845 ORF CAL0005765 PMID: 23689717|CGD_REF: CAL0000172329 homozygous diploid, classical genetics null Other C. albicans resistance to chemicals: increased plant defensin NaD1 C. albicans orf19.6846 ORF PHO85 CAL0005766 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.6846 ORF PHO85 CAL0005766 PMID: 17086158|CGD_REF: CAL0116909 homozygous diploid, classical genetics null Not recorded inviable homozygous null mutant strain could not be recovered, suggesting that the gene is essential under the selection conditions C. albicans orf19.6846 ORF PHO85 CAL0005766 PMID: 22365851|CGD_REF: CAL0000144076 heterozygous diploid, classical genetics repressible tetO-PHO85/pho85 (doxicyclin-repressible conditional mutant) SN95 filamentous growth: absent in response to Hsp90 inhibition C. albicans orf19.6846 ORF PHO85 CAL0005766 PMID: 22365851|CGD_REF: CAL0000144076 heterozygous diploid, classical genetics repressible tetO-PHO85/pho85 (doxicyclin-repressible conditional mutant) SN95 vegetative growth: decreased rate C. albicans orf19.6847 ORF CAL0005768 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.6847 ORF CAL0005768 PMID: 22438810|CGD_REF: CAL0000156986 homozygous diploid, classical genetics null BWP17 viable C. albicans orf19.6847 ORF CAL0005768 PMID: 22438810|CGD_REF: CAL0000156986 homozygous diploid, classical genetics null BWP17 virulence: decreased mutants have reduced capacity to damage oral epithelial cells in vitro model of infection (monolayers of oral epithelial cells) C. albicans orf19.6848 ORF VPS16 CAL0005772 PMID: 19040629|CGD_REF: CAL0121263 heterozygous diploid, classical genetics repressible CAI-4 filamentous growth: abnormal agar-slide cultures with serum forms pseudohyphae instead of true hyphae C. albicans orf19.6848 ORF VPS16 CAL0005772 PMID: 19040629|CGD_REF: CAL0121263 heterozygous diploid, classical genetics repressible Not recorded vacuolar morphology: abnormal diffuse vacuoles in yeast-like cells C. albicans orf19.6848 ORF VPS16 CAL0005772 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.6848 ORF VPS16 CAL0005772 PMID: 19040629|CGD_REF: CAL0121263 heterozygous diploid, classical genetics repressible CAI-4 hyphal growth: abnormal altered branching frequency in hyphae C. albicans orf19.6848 ORF VPS16 CAL0005772 PMID: 19040629|CGD_REF: CAL0121263 heterozygous diploid, classical genetics repressible CAI-4 hyphal growth: absent liquid serum-containing medium C. albicans orf19.6848 ORF VPS16 CAL0005772 PMID: 12524333|CGD_REF: CAL0080691 homozygous diploid, systematic mutation set (homozygous insertion mutants generated with URA3-ARG4-URA3 (UAU1) cassette) null BWP17 inviable homozygous null mutant strain could not be recovered, suggesting that the gene is essential under the selection conditions C. albicans orf19.6848 ORF VPS16 CAL0005772 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 invasive growth: decreased solid SLAD media C. albicans orf19.6850 ORF CAL0005790 PMID: 17555439|CGD_REF: CAL0117968 homozygous diploid, classical genetics null Not recorded survival rate in stationary phase: decreased C. albicans orf19.6850 ORF CAL0005790 PMID: 14663094|CGD_REF: CAL0080633 homozygous diploid, systematic mutation set (homozygous insertion mutants generated with URA3-ARG4-URA3 (UAU1) cassette) null BWP17 viable C. albicans orf19.6850 ORF CAL0005790 PMID: 15964282|CGD_REF: CAL0114274 homozygous diploid, systematic mutation set (split-marker transposon insertion strategy to disrupt both alleles) null BWP17 viable C. albicans orf19.6850 ORF CAL0005790 PMID: 15964282|CGD_REF: CAL0114274 homozygous diploid, systematic mutation set (split-marker transposon insertion strategy to disrupt both alleles) null BWP17 biofilm formation: normal C. albicans orf19.6854 ORF ATP1 CAL0005797 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient SC medium C. albicans orf19.6854 ORF ATP1 CAL0005797 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 invasive growth: decreased solid SLAD media C. albicans orf19.6858 ORF EDC3 CAL0005806 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.6858 ORF EDC3 CAL0005806 PMID: 14663094|CGD_REF: CAL0080633 homozygous diploid, systematic mutation set (homozygous insertion mutants generated with URA3-ARG4-URA3 (UAU1) cassette) null BWP17 viable C. albicans orf19.6858 ORF EDC3 CAL0005806 PMID: 22056521|CGD_REF: CAL0000143594 homozygous diploid, classical genetics null edc3::hph/edc3::hph BWP17 viable C. albicans orf19.6858 ORF EDC3 CAL0005806 PMID: 22056521|CGD_REF: CAL0000143594 homozygous diploid, classical genetics null edc3::hph/edc3::hph BWP17 filamentous growth: decreased C. albicans orf19.6860 ORF CAL0005824 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.6861 ORF CAL0005826 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.6861 ORF CAL0005826 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 invasive growth: decreased solid SLAD media C. albicans orf19.6862 ORF CAL0005828 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, competitive growth (haploinsufficient phenotype assay, barcode deletion set) null SC5314 resistance to chemicals: decreased 5-fluorouracil C. albicans orf19.6862 ORF CAL0005828 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, competitive growth (haploinsufficient phenotype assay, barcode deletion set) null SC5314 resistance to chemicals: decreased tubercidin C. albicans orf19.6862 ORF CAL0005828 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, competitive growth (haploinsufficient phenotype assay, barcode deletion set) null SC5314 resistance to chemicals: decreased flucytosine C. albicans orf19.6862 ORF CAL0005828 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.6862 ORF CAL0005828 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 invasive growth: decreased solid SLAD media C. albicans orf19.6863 ORF VPH1 CAL0005829 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.6863 ORF VPH1 CAL0005829 PMID: 23316054|CGD_REF: CAL0000158474 homozygous diploid, classical genetics null BWP17 viable C. albicans orf19.6863 ORF VPH1 CAL0005829 PMID: 23316054|CGD_REF: CAL0000158474 homozygous diploid, classical genetics null vph1::URA3/vph1::ARG4 BWP17 vacuolar morphology: abnormal C. albicans orf19.6863 ORF VPH1 CAL0005829 PMID: 23316054|CGD_REF: CAL0000158474 homozygous diploid, classical genetics null vph1::URA3/vph1::ARG4 BWP17 endocytosis: abnormal C. albicans orf19.6863 ORF VPH1 CAL0005829 PMID: 23316054|CGD_REF: CAL0000158474 homozygous diploid, classical genetics null vph1::URA3/vph1::ARG4p BWP17 protein secretion: decreased secreted protease and lipase activity C. albicans orf19.6863 ORF VPH1 CAL0005829 PMID: 23884420|CGD_REF: CAL0000172543 homozygous diploid, classical genetics null SN152 filamentous growth: decreased liquid Spider medium, with mannitol as carbon source reduction by 85% C. albicans orf19.6863 ORF VPH1 CAL0005829 PMID: 23884420|CGD_REF: CAL0000172543 homozygous diploid, classical genetics null SN152 virulence: decreased mouse intravenous infection C. albicans orf19.6864 ORF CAL0005832 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient SC medium C. albicans orf19.6868 ORF CAL0005844 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.6868 ORF CAL0005844 PMID: 20141603|CGD_REF: CAL0124951 homozygous diploid, systematic mutation set (homozygous insertion mutants generated with URA3-ARG4-URA3 (UAU1) cassette) null BWP17 colony appearance: abnormal 10% serum or Spider media at 37 deg C colonies are smoother than wild type but mutant is able to form true hyphae under liquid inducing conditions C. albicans orf19.6868 ORF CAL0005844 PMID: 20141603|CGD_REF: CAL0124951 homozygous diploid, systematic mutation set (homozygous insertion mutants generated with URA3-ARG4-URA3 (UAU1) cassette) null BWP17 viable C. albicans orf19.687.1 ORF RPL25 CAF0006909 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.687.1 ORF RPL25 CAF0006909 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 invasive growth: decreased solid SLAD media C. albicans orf19.6871 ORF CAL0005863 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.6874 ORF CAL0005869 PMID: 20041210|CGD_REF: CAL0124764 homozygous diploid, systematic mutation set null SN152 invasive growth: increased SD or YEPD media at 30 or 37 deg C strongly increased C. albicans orf19.6874 ORF CAL0005869 PMID: 20041210|CGD_REF: CAL0124764 homozygous diploid, systematic mutation set null SN152 colony appearance: abnormal Spider medium at 30 deg C enhanced peripheral invasion C. albicans orf19.6874 ORF CAL0005869 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.6874 ORF CAL0005869 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: abnormal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.6874 ORF CAL0005869 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.6874 ORF CAL0005869 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.6875 ORF VPS35 CAL0005872 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.6877 ORF PNG2 CAL0005876 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.6879 ORF CAL0005883 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.688 ORF CAL0001141 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.688 ORF CAL0001141 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient YNB medium C. albicans orf19.6880 ORF COG4 CAL0005896 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.6881 ORF YTH1 CAL0005897 PMID: 19623926|CGD_REF: CAL0124054 heterozygous diploid, competitive growth (haploinsufficient phenotype assay, barcode deletion set) null SC5314 resistance to chemicals: decreased parnafungin C. albicans orf19.6881 ORF YTH1 CAL0005897 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.6881 ORF YTH1 CAL0005897 PMID: 19623926|CGD_REF: CAL0124054 heterozygous diploid, competitive growth (haploinsufficient phenotype assay, barcode deletion set) null SC5314 resistance to chemicals: decreased cordycepin C. albicans orf19.6882 ORF OSM1 CAL0005898 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.6884 ORF GWT1 CAL0005901 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.6884 ORF GWT1 CAL0005901 PMID: 22143530|CGD_REF: CAL0000143699 homozygous diploid, classical genetics reduction of function Other C. albicans germ tube formation: decreased inhibition by E1210 anti fungal drug C. albicans orf19.6884 ORF GWT1 CAL0005901 PMID: 22143530|CGD_REF: CAL0000143699 homozygous diploid, classical genetics reduction of function Other C. albicans adhesion: decreased inhibition by E1210 anti fungal drug C. albicans orf19.6884 ORF GWT1 CAL0005901 PMID: 22143530|CGD_REF: CAL0000143699 homozygous diploid, classical genetics reduction of function Other C. albicans biofilm formation: decreased inhibition by E1210 anti fungal drug C. albicans orf19.6888 ORF CAL0005909 PMID: 22073120|CGD_REF: CAL0000143592 homozygous diploid, classical genetics null BWP17 viable C. albicans orf19.6888 ORF CAL0005909 PMID: 22073120|CGD_REF: CAL0000143592 homozygous diploid, classical genetics null BWP17 colony appearance: abnormal increased colony wrinkling C. albicans orf19.6889 ORF MKK2 CAL0005911 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.6889 ORF MKK2 CAL0005911 PMID: 14663094|CGD_REF: CAL0080633 homozygous diploid, systematic mutation set (homozygous insertion mutants generated with URA3-ARG4-URA3 (UAU1) cassette) null BWP17 viable C. albicans orf19.6889 ORF MKK2 CAL0005911 PMID: 20140194|CGD_REF: CAL0124995 homozygous diploid, classical genetics null Other C. albicans resistance to chemicals: decreased caspofungin C. albicans orf19.6889 ORF MKK2 CAL0005911 PMID: 20140194|CGD_REF: CAL0124995 homozygous diploid, classical genetics null Other C. albicans viable caspofungin C. albicans orf19.6889 ORF MKK2 CAL0005911 PMID: 20140194|CGD_REF: CAL0124995 homozygous diploid, classical genetics null Other C. albicans viable C. albicans orf19.689 ORF PLB1 CAL0001144 PMID: 9748287|CGD_REF: CAL0081674 homozygous diploid, classical genetics null Not recorded germ tube formation: normal C. albicans orf19.689 ORF PLB1 CAL0001144 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.689 ORF PLB1 CAL0001144 PMID: 14507372|CGD_REF: CAL0088818 heterozygous diploid, large-scale survey (large-scale identification of essential genes by gene replacement and conditional expression (GRACE) method) repressible CAI-4 viable one allele is deleted and the other is placed under repressible Tet promoter C. albicans orf19.689 ORF PLB1 CAL0001144 PMID: 11535799|CGD_REF: CAL0081689 heterozygous diploid, classical genetics null Not recorded viable reintegrant C. albicans orf19.689 ORF PLB1 CAL0001144 PMID: 9748287|CGD_REF: CAL0081674 heterozygous diploid, classical genetics null Not recorded viable C. albicans orf19.689 ORF PLB1 CAL0001144 PMID: 9748287|CGD_REF: CAL0081674 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.689 ORF PLB1 CAL0001144 PMID: 19839869|CGD_REF: CAL0124498 homozygous diploid, classical genetics null SC5314 virulence: decreased delayed tissue invasion rabbit corneal infection C. albicans orf19.689 ORF PLB1 CAL0001144 PMID: 9748287|CGD_REF: CAL0081674 homozygous diploid, classical genetics null Not recorded adhesion: normal adhesion to monolayers of endothelial or epithelial cells C. albicans orf19.689 ORF PLB1 CAL0001144 PMID: 9748287|CGD_REF: CAL0081674 homozygous diploid, classical genetics null Not recorded resistance to chemicals: normal amphotericin B C. albicans orf19.689 ORF PLB1 CAL0001144 PMID: 9748287|CGD_REF: CAL0081674 homozygous diploid, classical genetics null CAI-4 interaction with host/environment: decreased decreased capacity to penetrate cell monolayers, although adherence is wild-type in vitro model of infection (monolayers of endothelial or epithelial cells) C. albicans orf19.689 ORF PLB1 CAL0001144 PMID: 11535799|CGD_REF: CAL0081689 heterozygous diploid, classical genetics null Not recorded virulence: normal reintegrant mouse gastrointestinal tract infection C. albicans orf19.689 ORF PLB1 CAL0001144 PMID: 11535799|CGD_REF: CAL0081689 homozygous diploid, classical genetics null Not recorded virulence: decreased mouse gastrointestinal tract infection C. albicans orf19.689 ORF PLB1 CAL0001144 PMID: 9748287|CGD_REF: CAL0081674 homozygous diploid, classical genetics null Not recorded virulence: decreased exhibits decreased kidney and brain colonization mouse intravenous infection C. albicans orf19.689 ORF PLB1 CAL0001144 PMID: 11535799|CGD_REF: CAL0081689 heterozygous diploid, classical genetics null Not recorded virulence: normal reintegrant mouse intravenous infection C. albicans orf19.689 ORF PLB1 CAL0001144 PMID: 11535799|CGD_REF: CAL0081689 homozygous diploid, classical genetics null Not recorded virulence: decreased mouse intravenous infection C. albicans orf19.6891 ORF RFC1 CAL0005916 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.6891 ORF RFC1 CAL0005916 PMID: 12524333|CGD_REF: CAL0080691 homozygous diploid, systematic mutation set (homozygous insertion mutants generated with URA3-ARG4-URA3 (UAU1) cassette) null BWP17 inviable homozygous null mutant strain could not be recovered, suggesting that the gene is essential under the selection conditions C. albicans orf19.6893 ORF CAL0005917 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.6896 ORF CAL0005923 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 invasive growth: decreased solid SLAD media C. albicans orf19.6898 ORF CAL0005927 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.6899 ORF CAL0005929 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, competitive growth (haploinsufficient phenotype assay, barcode deletion set) null SC5314 resistance to chemicals: decreased ergosterol analogs (ECC69 and/or ECC1384) C. albicans orf19.6899 ORF CAL0005929 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.6899 ORF CAL0005929 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.6899 ORF CAL0005929 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.6899 ORF CAL0005929 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.6899 ORF CAL0005929 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.690 ORF PLB2 CAL0001160 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.6900 ORF CAL0000114 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.6902 ORF DBP7 CAL0000117 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.6902 ORF DBP7 CAL0000117 PMID: 20494978|CGD_REF: CAL0125636 heterozygous diploid, classical genetics null BWP17 resistance to chemicals: decreased clotrimazole (75 uM) growth in liquid culture confirmation of mutant phenotypes for heterozygous transposon insertion strains showing sensitivity in a large-scale assay C. albicans orf19.6903 ORF CAL0000118 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.6904 ORF GCN3 CAL0000120 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.6905 ORF CAL0000122 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.6906 ORF ASC1 CAL0000124 PMID: 20929924|CGD_REF: CAL0126497 homozygous diploid, classical genetics null BWP17 viable C. albicans orf19.6906 ORF ASC1 CAL0000124 PMID: 20929924|CGD_REF: CAL0126497 homozygous diploid, classical genetics null BWP17 virulence: decreased mouse intravenous infection C. albicans orf19.6906 ORF ASC1 CAL0000124 PMID: 20929924|CGD_REF: CAL0126497 homozygous diploid, classical genetics null BWP17 hyphal growth: abnormal iquid Lee's, serum-containing, or GlcNAc media abnormally short hyphal filaments C. albicans orf19.6906 ORF ASC1 CAL0000124 PMID: 20929924|CGD_REF: CAL0126497 homozygous diploid, classical genetics null BWP17 filamentous growth: absent liquid or solid SCLD or SLAD media (glucose or nitrogen starvation conditions) C. albicans orf19.6906 ORF ASC1 CAL0000124 PMID: 21221944|CGD_REF: CAL0141180 homozygous diploid, classical genetics null asc1::HIS1 BWP17 invasive growth: decreased C. albicans orf19.6906 ORF ASC1 CAL0000124 PMID: 21221944|CGD_REF: CAL0141180 homozygous diploid, classical genetics null asc1::HIS1 BWP17 adhesion: decreased C. albicans orf19.6906 ORF ASC1 CAL0000124 PMID: 21221944|CGD_REF: CAL0141180 homozygous diploid, classical genetics null asc1::HIS1 BWP17 virulence: decreased C. albicans orf19.6907 ORF CAL0000127 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.6908 ORF CAL0000131 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.6908 ORF CAL0000131 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient YPD medium C. albicans orf19.6908 ORF CAL0000131 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient YNB medium C. albicans orf19.6908 ORF CAL0000131 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient SLAD medium C. albicans orf19.6909 ORF CAL0000135 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.691 ORF GPD2 CAL0001161 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.691 ORF GPD2 CAL0001161 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.691 ORF GPD2 CAL0001161 PMID: 21407800|CGD_REF: CAL0141800 homozygous diploid, large-scale survey null BWP17 interaction with host/environment: abnormal significantly reduced damage to epithelial cells, but normal adhesion and invasion ex vivo model of infection C. albicans orf19.691 ORF GPD2 CAL0001161 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.691 ORF GPD2 CAL0001161 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.691 ORF GPD2 CAL0001161 PMID: 23572557|CGD_REF: CAL0000158900 homozygous diploid, classical genetics null SN152 adhesion: decreased Fluxion Bioflux 200, equipped with a microscope, was used for adherence analysis allowing a constant flow of cells through microfluidic channels C. albicans orf19.691 ORF GPD2 CAL0001161 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.6910 ORF PSF1 CAL0000155 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.6912 ORF CAL0000158 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.6913 ORF GCN2 CAL0000160 PMID: 16215176|CGD_REF: CAL0114837 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased 3-aminotriazole C. albicans orf19.6913 ORF GCN2 CAL0000160 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.6913 ORF GCN2 CAL0000160 PMID: 16215176|CGD_REF: CAL0114837 heterozygous diploid, classical genetics null Not recorded viable C. albicans orf19.6913 ORF GCN2 CAL0000160 PMID: 16215176|CGD_REF: CAL0114837 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.6913 ORF GCN2 CAL0000160 PMID: 22406769|CGD_REF: CAL0000156984 homozygous diploid, classical genetics null gcn2::hisG/gcn2::HisG-URA3-HisG CAI-4 viable C. albicans orf19.6913 ORF GCN2 CAL0000160 PMID: 22406769|CGD_REF: CAL0000156984 homozygous diploid, classical genetics null gcn2::hisG/gcn2::HisG-URA3-HisG CAI-4 filamentous growth: decreased N-acetyl-D-glucosamine mutant is not filamentous on GlcNAc C. albicans orf19.6913 ORF GCN2 CAL0000160 PMID: 22406769|CGD_REF: CAL0000156984 homozygous diploid, classical genetics null gcn2::hisG/gcn2::HisG-URA3-HisG CAI-4 colony size: decreased C. albicans orf19.6913 ORF GCN2 CAL0000160 PMID: 22406769|CGD_REF: CAL0000156984 homozygous diploid, classical genetics null gcn2::hisG/gcn2::HisG-URA3-HisG CAI-4 colony shape: abnormal forms smooth colonies on GlcNAc medium instead of filamentous colonies as does wild-type C. albicans orf19.6913 ORF GCN2 CAL0000160 PMID: 22406769|CGD_REF: CAL0000156984 homozygous diploid, classical genetics null gcn2::hisG/gcn2::HisG-URA3-HisG CAI-4 protein/peptide modification: decreased more than two fold increased phosphorylation of eIF2alpha was observed in response to GlcNAc as compared to that of glucose, no detectable phosphorylation of eIF2alpha was observed in the gcn2 mutant strain eIF2alpha C. albicans orf19.6915 ORF MRE11 CAL0000164 PMID: 17965250|CGD_REF: CAL0118884 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased camptothecin C. albicans orf19.6915 ORF MRE11 CAL0000164 PMID: 17965250|CGD_REF: CAL0118884 homozygous diploid, classical genetics null Not recorded UV resistance: decreased C. albicans orf19.6915 ORF MRE11 CAL0000164 PMID: 17965250|CGD_REF: CAL0118884 homozygous diploid, classical genetics null Not recorded vegetative growth: decreased rate C. albicans orf19.6915 ORF MRE11 CAL0000164 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.6915 ORF MRE11 CAL0000164 PMID: 17965250|CGD_REF: CAL0118884 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.6915 ORF MRE11 CAL0000164 PMID: 17965250|CGD_REF: CAL0118884 homozygous diploid, classical genetics null Not recorded oxidative stress resistance: decreased hydrogen peroxide C. albicans orf19.6915 ORF MRE11 CAL0000164 PMID: 17965250|CGD_REF: CAL0118884 homozygous diploid, classical genetics null Not recorded cell size: increased C. albicans orf19.6915 ORF MRE11 CAL0000164 PMID: 17965250|CGD_REF: CAL0118884 homozygous diploid, classical genetics null Not recorded chromosome segregation: abnormal increased chromosome instability C. albicans orf19.6915 ORF MRE11 CAL0000164 PMID: 17965250|CGD_REF: CAL0118884 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased ethyl methanesulfonate C. albicans orf19.6915 ORF MRE11 CAL0000164 PMID: 17965250|CGD_REF: CAL0118884 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased methyl methanesulfonate C. albicans orf19.6915 ORF MRE11 CAL0000164 PMID: 17965250|CGD_REF: CAL0118884 homozygous diploid, classical genetics null Not recorded oxidative stress resistance: decreased tert-butyl hydroperoxide C. albicans orf19.6915 ORF MRE11 CAL0000164 PMID: 17965250|CGD_REF: CAL0118884 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased fluconazole C. albicans orf19.6916 ORF CAL0000167 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.6917 ORF CAL0000169 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.6923 ORF CAL0000201 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.6924 ORF HTA1 CAL0000204 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.6925 ORF HTB1 CAL0000206 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.6926 ORF CSC25 CAL0000207 PMID: 12773383|CGD_REF: CAL0087974 heterozygous diploid, classical genetics (haploinsufficient phenotype assay) unspecified CAI-4 filamentous growth: abnormal transposon insertion proximal to, but not within, the ORF C. albicans orf19.6926 ORF CSC25 CAL0000207 PMID: 11004171|CGD_REF: CAL0080680 homozygous diploid, classical genetics null Not recorded filamentous growth: decreased solid serum-containing medium C. albicans orf19.6926 ORF CSC25 CAL0000207 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.6926 ORF CSC25 CAL0000207 PMID: 14507372|CGD_REF: CAL0088818 heterozygous diploid, large-scale survey (large-scale identification of essential genes by gene replacement and conditional expression (GRACE) method) repressible CAI-4 viable one allele is deleted and the other is placed under repressible Tet promoter C. albicans orf19.6926 ORF CSC25 CAL0000207 PMID: 11004171|CGD_REF: CAL0080680 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.6927 ORF PEP8 CAL0000210 PMID: 12773383|CGD_REF: CAL0087974 heterozygous diploid, classical genetics (haploinsufficient phenotype assay) unspecified CAI-4 filamentous growth: abnormal transposon insertion proximal to, but not within, the ORF C. albicans orf19.6927 ORF PEP8 CAL0000210 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.6927 ORF PEP8 CAL0000210 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: abnormal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.6927 ORF PEP8 CAL0000210 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.6927 ORF PEP8 CAL0000210 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.6928 ORF SAP9 CAL0000212 PMID: 16269404|CGD_REF: CAL0115363 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased Hygromycin B C. albicans orf19.6928 ORF SAP9 CAL0000212 PMID: 16269404|CGD_REF: CAL0115363 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased amorolfine C. albicans orf19.6928 ORF SAP9 CAL0000212 PMID: 16269404|CGD_REF: CAL0115363 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased nikkomycin Z C. albicans orf19.6928 ORF SAP9 CAL0000212 PMID: 16269404|CGD_REF: CAL0115363 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased Calcofluor White C. albicans orf19.6928 ORF SAP9 CAL0000212 PMID: 16269404|CGD_REF: CAL0115363 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased itraconazole C. albicans orf19.6928 ORF SAP9 CAL0000212 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.6928 ORF SAP9 CAL0000212 PMID: 15820985|CGD_REF: CAL0082498 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.6928 ORF SAP9 CAL0000212 PMID: 16269404|CGD_REF: CAL0115363 heterozygous diploid, classical genetics null Not recorded viable C. albicans orf19.6928 ORF SAP9 CAL0000212 PMID: 16269404|CGD_REF: CAL0115363 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.6928 ORF SAP9 CAL0000212 PMID: 18765290|CGD_REF: CAL0119430 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.6928 ORF SAP9 CAL0000212 PMID: 16269404|CGD_REF: CAL0115363 homozygous diploid, classical genetics null Not recorded adhesion: increased adhesion to human buccal epithelial cells C. albicans orf19.6928 ORF SAP9 CAL0000212 PMID: 16269404|CGD_REF: CAL0115363 homozygous diploid, classical genetics null Not recorded chitin deposition: increased increased cell wall chitin C. albicans orf19.6928 ORF SAP9 CAL0000212 PMID: 16269404|CGD_REF: CAL0115363 homozygous diploid, classical genetics null Not recorded cytokinesis: absent C. albicans orf19.6928 ORF SAP9 CAL0000212 PMID: 16269404|CGD_REF: CAL0115363 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased Congo Red C. albicans orf19.6928 ORF SAP9 CAL0000212 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.6928 ORF SAP9 CAL0000212 PMID: 19805528|CGD_REF: CAL0124359 homozygous diploid, classical genetics null CAI-4 resistance to killing by host cells: decreased survival at 3 hrs post-incubation with PMNs is 88% compared to wild-type survival of 47% in vitro model of infection (human PMNs) C. albicans orf19.6928 ORF SAP9 CAL0000212 PMID: 21097664|CGD_REF: CAL0139899 homozygous diploid, classical genetics null CAI-4 resistance to phagocytosis: normal in vitro model of infection (human macrophages) C. albicans orf19.6928 ORF SAP9 CAL0000212 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.6928 ORF SAP9 CAL0000212 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.6928 ORF SAP9 CAL0000212 PMID: 16269404|CGD_REF: CAL0115363 homozygous diploid, classical genetics null Not recorded virulence: decreased reconstituted human epithelium ex vivo model of infection C. albicans orf19.6928 ORF SAP9 CAL0000212 PMID: 16269404|CGD_REF: CAL0115363 homozygous diploid, classical genetics null Not recorded virulence: decreased mouse intravenous infection C. albicans orf19.6928 ORF SAP9 CAL0000212 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.6930 ORF SOL1 CAL0000229 PMID: 15814839|CGD_REF: CAL0114183 homozygous diploid, classical genetics null CAI-4 germ tube formation: normal serum-containing medium C. albicans orf19.6930 ORF SOL1 CAL0000229 PMID: 15814839|CGD_REF: CAL0114183 homozygous diploid, classical genetics null Not recorded vegetative growth: decreased rate C. albicans orf19.6930 ORF SOL1 CAL0000229 PMID: 15814839|CGD_REF: CAL0114183 heterozygous diploid, classical genetics overexpression Not recorded viable wild-type cell morphology C. albicans orf19.6930 ORF SOL1 CAL0000229 PMID: 15814839|CGD_REF: CAL0114183 heterozygous diploid, classical genetics null Not recorded viable C. albicans orf19.6930 ORF SOL1 CAL0000229 PMID: 15814839|CGD_REF: CAL0114183 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.6930 ORF SOL1 CAL0000229 PMID: 15814839|CGD_REF: CAL0114183 homozygous diploid, classical genetics null Not recorded bud morphology: abnormal some buds are elongated C. albicans orf19.6930 ORF SOL1 CAL0000229 PMID: 15814839|CGD_REF: CAL0114183 heterozygous diploid, classical genetics null Not recorded bud morphology: abnormal some buds are elongated; phenotype is less severe than that of the homozygous null mutant C. albicans orf19.6930 ORF SOL1 CAL0000229 PMID: 15814839|CGD_REF: CAL0114183 homozygous diploid, classical genetics null Not recorded cell size: increased some cells are enlarged C. albicans orf19.6931 ORF CAL0000231 PMID: 19623926|CGD_REF: CAL0124054 heterozygous diploid, competitive growth (haploinsufficient phenotype assay, barcode deletion set) null SC5314 resistance to chemicals: decreased parnafungin C. albicans orf19.6931 ORF CAL0000231 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.6931 ORF CAL0000231 PMID: 19623926|CGD_REF: CAL0124054 heterozygous diploid, competitive growth (haploinsufficient phenotype assay, barcode deletion set) null SC5314 resistance to chemicals: decreased cordycepin C. albicans orf19.6931 ORF CAL0000231 PMID: 21135205|CGD_REF: CAL0139967 heterozygous diploid, large-scale survey (large-scale identification of genes essential for virulence in mouse) repressible CAI-4 virulence: absent mouse intravenous infection C. albicans orf19.6933 ORF CAL0000234 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.6936 ORF RAD53 CAL0000242 PMID: 17182857|CGD_REF: CAL0117321 homozygous diploid, classical genetics null Not recorded vegetative growth: decreased rate C. albicans orf19.6936 ORF RAD53 CAL0000242 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.6936 ORF RAD53 CAL0000242 PMID: 17182857|CGD_REF: CAL0117321 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.6936 ORF RAD53 CAL0000242 PMID: 17182857|CGD_REF: CAL0117321 homozygous diploid, classical genetics null BWP17 hyphal growth: decreased serum-containing medium C. albicans orf19.6936 ORF RAD53 CAL0000242 PMID: 17182857|CGD_REF: CAL0117321 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased methyl methanesulfonate C. albicans orf19.6936 ORF RAD53 CAL0000242 PMID: 17182857|CGD_REF: CAL0117321 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased hydroxyurea C. albicans orf19.6937 ORF PTR22 CAL0000244 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.6937 ORF PTR22 CAL0000244 PMID: 21414038|CGD_REF: CAL0141808 homozygous diploid, classical genetics null BWP17 viable C. albicans orf19.6937 ORF PTR22 CAL0000244 PMID: 23376942|CGD_REF: CAL0000158493 homozygous diploid, classical genetics null SC5314 viable C. albicans orf19.6938 ORF MEU1 CAL0000248 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient SLAD medium C. albicans orf19.6942 ORF ORC3 CAL0000266 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, competitive growth (haploinsufficient phenotype assay, barcode deletion set) null SC5314 resistance to chemicals: decreased ergosterol analogs (ECC69 and/or ECC1384) C. albicans orf19.6942 ORF ORC3 CAL0000266 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.6948 ORF CCC1 CAL0000278 PMID: 19779551|CGD_REF: CAL0124331 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.6948 ORF CCC1 CAL0000278 PMID: 19779551|CGD_REF: CAL0124331 homozygous diploid, classical genetics null Not recorded colony appearance: abnormal solid Spider medium C. albicans orf19.6948 ORF CCC1 CAL0000278 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.6948 ORF CCC1 CAL0000278 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.6948 ORF CCC1 CAL0000278 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.6948 ORF CCC1 CAL0000278 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 invasive growth: decreased solid SLAD media C. albicans orf19.6948 ORF CCC1 CAL0000278 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.695 ORF RGS2 CAL0001166 PMID: 14663094|CGD_REF: CAL0080633 homozygous diploid, systematic mutation set (homozygous insertion mutants generated with URA3-ARG4-URA3 (UAU1) cassette) null BWP17 viable C. albicans orf19.695 ORF RGS2 CAL0001166 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.695 ORF RGS2 CAL0001166 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: abnormal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.695 ORF RGS2 CAL0001166 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.695 ORF RGS2 CAL0001166 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.6950 ORF CAL0000296 PMID: 14663094|CGD_REF: CAL0080633 homozygous diploid, systematic mutation set (homozygous insertion mutants generated with URA3-ARG4-URA3 (UAU1) cassette) null BWP17 viable C. albicans orf19.6951 ORF CAL0000297 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.6951 ORF CAL0000297 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.6951 ORF CAL0000297 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.6951 ORF CAL0000297 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.6951 ORF CAL0000297 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.6952 ORF CAL0000298 PMID: 14663094|CGD_REF: CAL0080633 homozygous diploid, systematic mutation set (homozygous insertion mutants generated with URA3-ARG4-URA3 (UAU1) cassette) null BWP17 viable C. albicans orf19.6952 ORF CAL0000298 PMID: 23856128|CGD_REF: CAL0000172540 homozygous diploid, classical genetics null BWP17 resistance to chemicals: decreased propolis C. albicans orf19.6953 ORF IRS4 CAL0000299 PMID: 16151204|CGD_REF: CAL0114705 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased caspofungin C. albicans orf19.6953 ORF IRS4 CAL0000299 PMID: 16151204|CGD_REF: CAL0114705 homozygous diploid, classical genetics null Not recorded resistance to enzymatic treatment: decreased zymolyase C. albicans orf19.6953 ORF IRS4 CAL0000299 PMID: 16151204|CGD_REF: CAL0114705 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased Calcofluor White C. albicans orf19.6953 ORF IRS4 CAL0000299 PMID: 16151204|CGD_REF: CAL0114705 heterozygous diploid, classical genetics null Not recorded viable C. albicans orf19.6953 ORF IRS4 CAL0000299 PMID: 16151204|CGD_REF: CAL0114705 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.6953 ORF IRS4 CAL0000299 PMID: 16151204|CGD_REF: CAL0114705 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased sodium dodecyl sulfate C. albicans orf19.6953 ORF IRS4 CAL0000299 PMID: 16151204|CGD_REF: CAL0114705 homozygous diploid, classical genetics null Not recorded adhesion: decreased adhesion to FaDu, HeLa cervical, and HT-29 colonic cell lines C. albicans orf19.6953 ORF IRS4 CAL0000299 PMID: 16151204|CGD_REF: CAL0114705 heterozygous diploid, classical genetics null CAI-4 hyphal growth: decreased on solid agar or embedded within agar phenotype is intermediate between that of wild type and the homozygous null mutant C. albicans orf19.6953 ORF IRS4 CAL0000299 PMID: 16151204|CGD_REF: CAL0114705 homozygous diploid, classical genetics null CAI-4 hyphal growth: normal liquid media C. albicans orf19.6953 ORF IRS4 CAL0000299 PMID: 16151204|CGD_REF: CAL0114705 homozygous diploid, classical genetics null CAI-4 hyphal growth: decreased on solid agar or embedded within agar C. albicans orf19.6953 ORF IRS4 CAL0000299 PMID: 18957583|CGD_REF: CAL0120459 homozygous diploid, classical genetics null Not recorded chemical compound accumulation: increased phosphoinositide C. albicans orf19.6953 ORF IRS4 CAL0000299 PMID: 16151204|CGD_REF: CAL0114705 homozygous diploid, classical genetics null Not recorded chitin deposition: abnormal abnormal chitin distribution in hyphal cell walls during agar-embedded growth but not during growth in liquid media C. albicans orf19.6953 ORF IRS4 CAL0000299 PMID: 16151204|CGD_REF: CAL0114705 homozygous diploid, classical genetics null Not recorded virulence: decreased mouse intravenous infection C. albicans orf19.6953 ORF IRS4 CAL0000299 PMID: 16151204|CGD_REF: CAL0114705 heterozygous diploid, classical genetics null Not recorded virulence: normal mouse intravenous infection C. albicans orf19.6953 ORF IRS4 CAL0000299 PMID: 16151204|CGD_REF: CAL0114705 homozygous diploid, classical genetics null Not recorded virulence: normal immunocompromised mice mouse oropharyngeal infection C. albicans orf19.6955 ORF HBR3 CAL0000302 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.6955 ORF HBR3 CAL0000302 PMID: 16607011|CGD_REF: CAL0115846 heterozygous diploid, classical genetics null SC5314 viable C. albicans orf19.6955 ORF HBR3 CAL0000302 PMID: 16607011|CGD_REF: CAL0115846 homozygous diploid, classical genetics null SC5314 inviable homozygous null mutant strain could not be recovered, suggesting that the gene is essential under the selection conditions C. albicans orf19.6955 ORF HBR3 CAL0000302 PMID: 16607011|CGD_REF: CAL0115846 heterozygous diploid, classical genetics repressible SC5314 inviable C. albicans orf19.6955 ORF HBR3 CAL0000302 PMID: 21135205|CGD_REF: CAL0139967 heterozygous diploid, competitive growth (large-scale identification of genes essential for virulence in mouse) repressible CAI-4 virulence: decreased mouse intravenous infection C. albicans orf19.6956 ORF DAL9 CAL0000305 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.6958 ORF ECM18 CAL0000311 PMID: 17873081|CGD_REF: CAL0118685 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.6958 ORF ECM18 CAL0000311 PMID: 17873081|CGD_REF: CAL0118685 homozygous diploid, classical genetics null Not recorded inviable homozygous null mutant strain could not be recovered, suggesting that the gene is essential under the selection conditions C. albicans orf19.696 ORF STE2 CAL0001168 PMID: 21135205|CGD_REF: CAL0139967 heterozygous diploid, competitive growth (large-scale identification of genes essential for virulence in mouse) repressible CAI-4 virulence: normal mouse intravenous infection C. albicans orf19.696 ORF STE2 CAL0001168 PMID: 19170873|CGD_REF: CAL0122281 unknown ploidy, classical genetics unspecified P37005 viable series of deletion mutants; separable function of unique loop in a-specific white (nonmating) cell response to alpha pheromone C. albicans orf19.696 ORF STE2 CAL0001168 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.696 ORF STE2 CAL0001168 PMID: 19170873|CGD_REF: CAL0122281 homozygous diploid, classical genetics null P37005 adhesion: decreased adhesion to plastic C. albicans orf19.696 ORF STE2 CAL0001168 PMID: 14585977|CGD_REF: CAL0081534 homozygous diploid, classical genetics null CAI-4 viable C. albicans orf19.696 ORF STE2 CAL0001168 PMID: 19170873|CGD_REF: CAL0122281 homozygous diploid, classical genetics null P37005 biofilm formation: abnormal deletion of IC1 or IC3 loop or tail has null phenotype with respect to biofilm formation C. albicans orf19.696 ORF STE2 CAL0001168 PMID: 19170873|CGD_REF: CAL0122281 homozygous diploid, classical genetics null P37005 mating response: absent deletion of IC3 loop and tail has null phenotype with respect to shmooing, mating C. albicans orf19.696 ORF STE2 CAL0001168 PMID: 18162580|CGD_REF: CAL0118948 homozygous diploid, classical genetics null P37005 biofilm formation: decreased white cells form a biofilm of reduced thickness in the presence of opaque cells of the opposite mating type C. albicans orf19.696 ORF STE2 CAL0001168 PMID: 18162580|CGD_REF: CAL0118948 homozygous diploid, classical genetics null P37005 phenotypic switching: normal C. albicans orf19.696 ORF STE2 CAL0001168 PMID: 18162580|CGD_REF: CAL0118948 homozygous diploid, classical genetics null P37005 pheromone sensitivity: decreased alpha factor reduced aggregation of white-phase cells C. albicans orf19.696 ORF STE2 CAL0001168 PMID: 21498642|CGD_REF: CAL0141911 homozygous diploid, classical genetics null P37005 biofilm formation: decreased defect in white MTLa/MTLa cell biofilm formation C. albicans orf19.696 ORF STE2 CAL0001168 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.696 ORF STE2 CAL0001168 PMID: 21998194|CGD_REF: CAL0000143467 homozygous diploid, classical genetics null P37005 viable C. albicans orf19.696 ORF STE2 CAL0001168 PMID: 21998194|CGD_REF: CAL0000143467 homozygous diploid, classical genetics null P37005 mating response the third cytoplasmic loop (IC3) is critical for the response to α pheromone by opaque a cells C. albicans orf19.696 ORF STE2 CAL0001168 PMID: 21998194|CGD_REF: CAL0000143467 homozygous diploid, classical genetics null P37005 mating response: decreased the third cytoplasmic loop (IC3) is critical for the response to α pheromone by opaque a cells C. albicans orf19.696 ORF STE2 CAL0001168 PMID: 21998194|CGD_REF: CAL0000143467 homozygous diploid, classical genetics null P37005 shmoo formation: decreased mutants have a lower percentage of shmoos (43.2% and 61.4%) and shorter conjugation tubes (8.9 μm and 7.7 μm) than wildtype (97% shmooing, 31 μm projections) C. albicans orf19.696 ORF STE2 CAL0001168 PMID: 21998194|CGD_REF: CAL0000143467 homozygous diploid, classical genetics null P37005 cell cycle progression: increased IC3 and C-369 mutants lost the ability to undergo cell cycle arrest whereas C417 and C-392 mutants showed diminished arrest C. albicans orf19.696 ORF STE2 CAL0001168 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.696 ORF STE2 CAL0001168 PMID: 23637598|CGD_REF: CAL0000172002 homozygous diploid, classical genetics null a/a ste2/ste2 (opaque cells) P37005 mating projection morphology: abnormal 37 degrees C in Spider medium with gentle shakingS formation of mating projections are absent C. albicans orf19.696 ORF STE2 CAL0001168 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.6967 ORF USO6 CAL0000342 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.6970 ORF CAL0000362 PMID: 14663094|CGD_REF: CAL0080633 homozygous diploid, systematic mutation set (homozygous insertion mutants generated with URA3-ARG4-URA3 (UAU1) cassette) null BWP17 viable C. albicans orf19.6971 ORF DIE2 CAL0000363 PMID: 14663094|CGD_REF: CAL0080633 homozygous diploid, systematic mutation set (homozygous insertion mutants generated with URA3-ARG4-URA3 (UAU1) cassette) null BWP17 viable C. albicans orf19.6971 ORF DIE2 CAL0000363 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 invasive growth: decreased solid SLAD media C. albicans orf19.6973 ORF CAL0000366 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.6977 ORF GPI1 CAL0000374 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.698 ORF CAL0001174 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.698 ORF CAL0001174 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.698 ORF CAL0001174 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.698 ORF CAL0001174 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: decreased rate liquid synthetic complete medium C. albicans orf19.698 ORF CAL0001174 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.6980 ORF CAL0000391 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.6980 ORF CAL0000391 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: abnormal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.6980 ORF CAL0000391 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.6980 ORF CAL0000391 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.6981 ORF CAL0000392 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.6984 ORF CAL0000396 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.6985 ORF TEA1 CAL0000398 PMID: 20041210|CGD_REF: CAL0124764 homozygous diploid, systematic mutation set null SN152 resistance to chemicals: decreased flucytosine strongly sensitive C. albicans orf19.6985 ORF TEA1 CAL0000398 PMID: 15964282|CGD_REF: CAL0114274 homozygous diploid, systematic mutation set (split-marker transposon insertion strategy to disrupt both alleles) null BWP17 inviable homozygous null mutant strain could not be recovered, suggesting that the gene is essential under the selection conditions C. albicans orf19.6985 ORF TEA1 CAL0000398 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.6985 ORF TEA1 CAL0000398 PMID: 22073120|CGD_REF: CAL0000143592 homozygous diploid, classical genetics null BWP17 viable C. albicans orf19.6985 ORF TEA1 CAL0000398 PMID: 22073120|CGD_REF: CAL0000143592 homozygous diploid, classical genetics null BWP17 invasive growth: decreased decreased agar invasion C. albicans orf19.6985 ORF TEA1 CAL0000398 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.6985 ORF TEA1 CAL0000398 PMID: 22073120|CGD_REF: CAL0000143592 homozygous diploid, classical genetics null BWP17 viable C. albicans orf19.6985 ORF TEA1 CAL0000398 PMID: 22073120|CGD_REF: CAL0000143592 homozygous diploid, classical genetics null BWP17 colony appearance: abnormal decreased colony wrinkling C. albicans orf19.6985 ORF TEA1 CAL0000398 PMID: 22073120|CGD_REF: CAL0000143592 homozygous diploid, classical genetics null BWP17 viable C. albicans orf19.6985 ORF TEA1 CAL0000398 PMID: 22073120|CGD_REF: CAL0000143592 homozygous diploid, classical genetics null BWP17 hyphal growth: increased C. albicans orf19.6985 ORF TEA1 CAL0000398 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.6985 ORF TEA1 CAL0000398 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.6986 ORF CAL0000400 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.6987 ORF DNM1 CAL0000402 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.6988 ORF OST1 CAL0000404 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.6990 ORF CAL0000410 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.6990 ORF CAL0000410 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.6990 ORF CAL0000410 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.6990 ORF CAL0000410 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.6990 ORF CAL0000410 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.6992 ORF QDR2 CAL0000412 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.6992 ORF QDR2 CAL0000412 PMID: 24621232|CGD_REF: CAL0000173797 homozygous diploid, classical genetics null SC5314 biofilm formation: abnormal altered biofilm architecture and thickness C. albicans orf19.6992 ORF QDR2 CAL0000412 PMID: 24621232|CGD_REF: CAL0000173797 homozygous diploid, classical genetics null SC5314 virulence: decreased mouse intravenous infection C. albicans orf19.6993 ORF GAP2 CAL0000413 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.6995 ORF ATO6 CAL0000416 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.6996 ORF MNN14 CAL0000417 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.6996 ORF MNN14 CAL0000417 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.6996 ORF MNN14 CAL0000417 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.6996 ORF MNN14 CAL0000417 PMID: 23886038|CGD_REF: CAL0000172548 homozygous diploid, classical genetics null CAI-4 viable C. albicans orf19.6996 ORF MNN14 CAL0000417 PMID: 23886038|CGD_REF: CAL0000172548 homozygous diploid, classical genetics null CAI-4 filamentous growth: decreased 20% serum, or pH 6.5, or solid Spider medium C. albicans orf19.6996 ORF MNN14 CAL0000417 PMID: 23886038|CGD_REF: CAL0000172548 homozygous diploid, classical genetics null CAI-4 protein/peptide modification: decreased glycosylation HEX1 C. albicans orf19.6996 ORF MNN14 CAL0000417 PMID: 23886038|CGD_REF: CAL0000172548 homozygous diploid, classical genetics null CAI-4 resistance to chemicals: decreased sodium dodecyl sulfate C. albicans orf19.6996 ORF MNN14 CAL0000417 PMID: 23886038|CGD_REF: CAL0000172548 homozygous diploid, classical genetics null CAI-4 resistance to chemicals: decreased tunicamycin C. albicans orf19.6996 ORF MNN14 CAL0000417 PMID: 23886038|CGD_REF: CAL0000172548 homozygous diploid, classical genetics null CAI-4 resistance to chemicals: decreased hygromycin B C. albicans orf19.6996 ORF MNN14 CAL0000417 PMID: 23886038|CGD_REF: CAL0000172548 homozygous diploid, classical genetics null CAI-4 virulence: decreased mouse intravenous infection C. albicans orf19.6996 ORF MNN14 CAL0000417 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.700 ORF SEO1 CAL0001698 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.7001 ORF YCK2 CAL0001885 PMID: 19700637|CGD_REF: CAL0124157 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased protamine C. albicans orf19.7001 ORF YCK2 CAL0001885 PMID: 19700637|CGD_REF: CAL0124157 homozygous diploid, classical genetics null Not recorded toxin resistance: decreased human beta-defensin 2 C. albicans orf19.7001 ORF YCK2 CAL0001885 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.7001 ORF YCK2 CAL0001885 PMID: 19700637|CGD_REF: CAL0124157 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.7001 ORF YCK2 CAL0001885 PMID: 19700637|CGD_REF: CAL0124157 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased sodium dodecyl sulfate C. albicans orf19.7001 ORF YCK2 CAL0001885 PMID: 19700637|CGD_REF: CAL0124157 homozygous diploid, classical genetics null BWP17 hyphal growth: abnormal contact with oral epithelial cells, vascular endothelial cells, or polystyrene produces multiple short hyphae C. albicans orf19.7001 ORF YCK2 CAL0001885 PMID: 19700637|CGD_REF: CAL0124157 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased Congo Red C. albicans orf19.7001 ORF YCK2 CAL0001885 PMID: 19700637|CGD_REF: CAL0124157 homozygous diploid, classical genetics null Not recorded virulence: decreased oral epithelial cells decreased capacity to damage cells in vitro model of infection C. albicans orf19.7002 ORF CAL0001886 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.7009 ORF CAL0001897 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.701 ORF CFL11 CAL0001699 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.701 ORF CFL11 CAL0001699 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.701 ORF CFL11 CAL0001699 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: abnormal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.701 ORF CFL11 CAL0001699 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.701 ORF CFL11 CAL0001699 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.7011 ORF CAL0001929 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.7011 ORF CAL0001929 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 invasive growth: decreased solid SLAD media C. albicans orf19.7015 ORF RPP0 CAL0001932 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.7016 ORF PHM5 CAL0001934 PMID: 14663094|CGD_REF: CAL0080633 homozygous diploid, systematic mutation set (homozygous insertion mutants generated with URA3-ARG4-URA3 (UAU1) cassette) null BWP17 viable C. albicans orf19.7016 ORF PHM5 CAL0001934 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 invasive growth: decreased solid SLAD media C. albicans orf19.7017 ORF YOX1 CAL0001936 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.7017 ORF YOX1 CAL0001936 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.7017 ORF YOX1 CAL0001936 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.7017 ORF YOX1 CAL0001936 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.7018 ORF RPS18 CAL0001937 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient YNB medium C. albicans orf19.7018 ORF RPS18 CAL0001937 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient SLAD medium C. albicans orf19.7019 ORF YML6 CAL0001940 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.7019 ORF YML6 CAL0001940 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient SC medium C. albicans orf19.7019 ORF YML6 CAL0001940 PMID: 21135205|CGD_REF: CAL0139967 heterozygous diploid, competitive growth (large-scale identification of genes essential for virulence in mouse) repressible CAI-4 virulence: decreased mouse intravenous infection C. albicans orf19.702 ORF CAL0001700 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.7020 ORF CAL0001969 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.7020 ORF CAL0001969 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.7020 ORF CAL0001969 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.7020 ORF CAL0001969 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.7020 ORF CAL0001969 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.7021 ORF GPH1 CAL0001970 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.7023 ORF CAL0001972 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.7023 ORF CAL0001972 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.7023 ORF CAL0001972 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.7023 ORF CAL0001972 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.7025 ORF MCM1 CAL0001975 PMID: 12581351|CGD_REF: CAL0081309 heterozygous diploid, classical genetics repressible CAI-4 filamentous growth: abnormal rapid induction of pseudohyphae, followed by hyphae-like structures C. albicans orf19.7025 ORF MCM1 CAL0001975 PMID: 12581351|CGD_REF: CAL0081309 heterozygous diploid, classical genetics overexpression CAI-4 flocculation: increased enhanced cell-cell adhesion C. albicans orf19.7025 ORF MCM1 CAL0001975 PMID: 15964282|CGD_REF: CAL0114274 homozygous diploid, systematic mutation set (split-marker transposon insertion strategy to disrupt both alleles) null BWP17 viable C. albicans orf19.7025 ORF MCM1 CAL0001975 PMID: 15964282|CGD_REF: CAL0114274 homozygous diploid, systematic mutation set (split-marker transposon insertion strategy to disrupt both alleles) null BWP17 biofilm formation: normal C. albicans orf19.7025 ORF MCM1 CAL0001975 PMID: 12581351|CGD_REF: CAL0081309 heterozygous diploid, classical genetics overexpression CAI-4 hyphal growth: increased solid Lee's medium C. albicans orf19.7025 ORF MCM1 CAL0001975 PMID: 12581351|CGD_REF: CAL0081309 homozygous diploid, classical genetics null Not recorded inviable C. albicans orf19.7025 ORF MCM1 CAL0001975 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 invasive growth: decreased solid SLAD media C. albicans orf19.7029 ORF CAL0001982 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, competitive growth (haploinsufficient phenotype assay, barcode deletion set) null SC5314 resistance to chemicals: decreased ergosterol analogs (ECC69 and/or ECC1384) C. albicans orf19.7029 ORF CAL0001982 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.7030 ORF SSR1 CAL0002011 PMID: 18765290|CGD_REF: CAL0119430 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased caspofungin C. albicans orf19.7030 ORF SSR1 CAL0002011 PMID: 12904553|CGD_REF: CAL0081943 homozygous diploid, classical genetics null Not recorded resistance to enzymatic treatment: decreased zymolyase C. albicans orf19.7030 ORF SSR1 CAL0002011 PMID: 12904553|CGD_REF: CAL0081943 heterozygous diploid, classical genetics overexpression Not recorded resistance to enzymatic treatment: decreased zymolyase C. albicans orf19.7030 ORF SSR1 CAL0002011 PMID: 12904553|CGD_REF: CAL0081943 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased Calcofluor White C. albicans orf19.7030 ORF SSR1 CAL0002011 PMID: 18765290|CGD_REF: CAL0119430 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased Calcofluor White C. albicans orf19.7030 ORF SSR1 CAL0002011 PMID: 12904553|CGD_REF: CAL0081943 homozygous diploid, classical genetics null Not recorded viable wild-type growth rate C. albicans orf19.7030 ORF SSR1 CAL0002011 PMID: 12904553|CGD_REF: CAL0081943 heterozygous diploid, classical genetics overexpression Not recorded viable wild-type growth rate C. albicans orf19.7030 ORF SSR1 CAL0002011 PMID: 18765290|CGD_REF: CAL0119430 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.7030 ORF SSR1 CAL0002011 PMID: 18765290|CGD_REF: CAL0119430 homozygous diploid, classical genetics null Not recorded cell wall morphology: abnormal decreased thickness C. albicans orf19.7030 ORF SSR1 CAL0002011 PMID: 12904553|CGD_REF: CAL0081943 homozygous diploid, classical genetics null Not recorded cellular morphology: normal C. albicans orf19.7030 ORF SSR1 CAL0002011 PMID: 12904553|CGD_REF: CAL0081943 heterozygous diploid, classical genetics overexpression Not recorded cellular morphology: normal C. albicans orf19.7030 ORF SSR1 CAL0002011 PMID: 12904553|CGD_REF: CAL0081943 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased Congo Red C. albicans orf19.7030 ORF SSR1 CAL0002011 PMID: 18765290|CGD_REF: CAL0119430 homozygous diploid, classical genetics null Not recorded chemical compound accumulation: increased glucan increased cell wall glucan C. albicans orf19.7030 ORF SSR1 CAL0002011 PMID: 16024227|CGD_REF: CAL0114862 homozygous diploid, classical genetics null Not recorded chemical compound accumulation: increased (1->3)-beta-D-glucan increased cell wall beta-1,3-glucan C. albicans orf19.7030 ORF SSR1 CAL0002011 PMID: 16024227|CGD_REF: CAL0114862 homozygous diploid, classical genetics null CAI-4 viable C. albicans orf19.7033 ORF CAL0002013 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.7033 ORF CAL0002013 PMID: 18708562|CGD_REF: CAL0119375 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.7033 ORF CAL0002013 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.7033 ORF CAL0002013 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.7033 ORF CAL0002013 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.7033 ORF CAL0002013 PMID: 18708562|CGD_REF: CAL0119375 homozygous diploid, classical genetics null Not recorded virulence: normal silkworm insect infection C. albicans orf19.7033 ORF CAL0002013 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.7035 ORF RFC2 CAL0002015 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.7037 ORF YAE1 CAL0002018 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.7037 ORF YAE1 CAL0002018 PMID: 14507372|CGD_REF: CAL0088818 heterozygous diploid, large-scale survey (large-scale identification of essential genes by gene replacement and conditional expression (GRACE) method) repressible CAI-4 viable one allele is deleted and the other is placed under repressible Tet promoter C. albicans orf19.704 ORF SOL3 CAL0001702 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.7041 ORF CAL0002053 PMID: 19623926|CGD_REF: CAL0124054 heterozygous diploid, competitive growth (haploinsufficient phenotype assay, barcode deletion set) null SC5314 resistance to chemicals: decreased parnafungin C. albicans orf19.7041 ORF CAL0002053 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.7041 ORF CAL0002053 PMID: 19623926|CGD_REF: CAL0124054 heterozygous diploid, competitive growth (haploinsufficient phenotype assay, barcode deletion set) null SC5314 resistance to chemicals: decreased cordycepin C. albicans orf19.7041 ORF CAL0002053 PMID: 21135205|CGD_REF: CAL0139967 heterozygous diploid, large-scale survey (large-scale identification of genes essential for virulence in mouse) repressible CAI-4 virulence: absent mouse intravenous infection C. albicans orf19.7043.1 ORF ACB1 CAF0007094 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient YPD medium C. albicans orf19.7043.1 ORF ACB1 CAF0007094 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient SLAD medium C. albicans orf19.7044 ORF RIM15 CAL0002056 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.7044 ORF RIM15 CAL0002056 PMID: 21335533|CGD_REF: CAL0141646 homozygous diploid, classical genetics null rim15::hisG/rim15::hisG CAI-4 viable C. albicans orf19.7044 ORF RIM15 CAL0002056 PMID: 21335533|CGD_REF: CAL0141646 homozygous diploid, classical genetics null rim15::hisG/rim15::hisG CAI-4 chronological lifespan: decreased under normal oxygen levels C. albicans orf19.7044 ORF RIM15 CAL0002056 PMID: 23856128|CGD_REF: CAL0000172540 homozygous diploid, classical genetics null BWP17 resistance to chemicals: decreased propolis C. albicans orf19.7049 ORF CYB5 CAL0002061 PMID: 15328107|CGD_REF: CAL0082077 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased ketoconazole C. albicans orf19.7049 ORF CYB5 CAL0002061 PMID: 15328107|CGD_REF: CAL0082077 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased terbinafine C. albicans orf19.7049 ORF CYB5 CAL0002061 PMID: 15328107|CGD_REF: CAL0082077 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased itraconazole C. albicans orf19.7049 ORF CYB5 CAL0002061 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.7049 ORF CYB5 CAL0002061 PMID: 15328107|CGD_REF: CAL0082077 heterozygous diploid, classical genetics null Not recorded viable C. albicans orf19.7049 ORF CYB5 CAL0002061 PMID: 15328107|CGD_REF: CAL0082077 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.7049 ORF CYB5 CAL0002061 PMID: 15328107|CGD_REF: CAL0082077 homozygous diploid, classical genetics null Not recorded resistance to chemicals: increased morpholines C. albicans orf19.7049 ORF CYB5 CAL0002061 PMID: 15328107|CGD_REF: CAL0082077 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased fluconazole C. albicans orf19.7049 ORF CYB5 CAL0002061 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: decreased growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.7049 ORF CYB5 CAL0002061 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.7049 ORF CYB5 CAL0002061 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.7049 ORF CYB5 CAL0002061 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.705 ORF GCN5 CAL0001703 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, competitive growth (haploinsufficient phenotype assay, barcode deletion set) null SC5314 resistance to chemicals: decreased 5-fluorouracil C. albicans orf19.705 ORF GCN5 CAL0001703 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.7050 ORF NOP15 CAL0002077 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.7050 ORF NOP15 CAL0002077 PMID: 21135205|CGD_REF: CAL0139967 heterozygous diploid, competitive growth (large-scale identification of genes essential for virulence in mouse) repressible CAI-4 virulence: decreased mouse intravenous infection C. albicans orf19.7052 ORF CAL0002079 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.7052 ORF CAL0002079 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient YNB medium C. albicans orf19.7056 ORF CAL0002083 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.7057 ORF GUS1 CAL0002084 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.7057 ORF GUS1 CAL0002084 PMID: 21135205|CGD_REF: CAL0139967 heterozygous diploid, large-scale survey (large-scale identification of genes essential for virulence in mouse) repressible CAI-4 virulence: absent mouse intravenous infection C. albicans orf19.7058 ORF CAL0002085 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.706 ORF NMD3 CAL0001704 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.706 ORF NMD3 CAL0001704 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 invasive growth: decreased solid SLAD media C. albicans orf19.7061 ORF CAL0002107 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.7062 ORF RPA135 CAL0002109 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.7064 ORF GLN4 CAL0002113 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.7067 ORF CAL0002116 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.7068 ORF MAC1 CAL0002117 PMID: 20041210|CGD_REF: CAL0124764 homozygous diploid, systematic mutation set null SN152 resistance to chemicals: decreased BPS (150 uM bathophenanthrolinedisulfonic?acid, an iron chelator) strongly sensitive C. albicans orf19.7068 ORF MAC1 CAL0002117 PMID: 15256562|CGD_REF: CAL0082101 homozygous diploid, classical genetics null Not recorded respiratory growth: absent unable to utilize nonfermentable carbon sources glycerol or ethanol; defect is rescued by exogenous cupric chloride C. albicans orf19.7068 ORF MAC1 CAL0002117 PMID: 15256562|CGD_REF: CAL0082101 homozygous diploid, classical genetics null Not recorded vegetative growth: decreased rate low-copper or low-iron media growth defect is rescued by cupric chloride C. albicans orf19.7068 ORF MAC1 CAL0002117 PMID: 20041210|CGD_REF: CAL0124764 homozygous diploid, systematic mutation set null SN152 vegetative growth: decreased Spider medium at 30 deg C, or blood agar at 37 deg C severely decreased C. albicans orf19.7068 ORF MAC1 CAL0002117 PMID: 20041210|CGD_REF: CAL0124764 homozygous diploid, systematic mutation set null SN152 vegetative growth: decreased YEPD medium at 30 deg C strongly decreased C. albicans orf19.7068 ORF MAC1 CAL0002117 PMID: 15256562|CGD_REF: CAL0082101 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.7068 ORF MAC1 CAL0002117 PMID: 15256562|CGD_REF: CAL0082101 homozygous diploid, classical genetics null BWP17 hyphal growth: normal serum-containing medium at 37 deg C C. albicans orf19.7068 ORF MAC1 CAL0002117 PMID: 20041210|CGD_REF: CAL0124764 homozygous diploid, systematic mutation set null SN152 colony appearance: abnormal YEPD medium at 42 deg C, or YEPD plus serum at 37 deg C strongly decreased colony fuzziness and/or peripheral filamentation C. albicans orf19.7069 ORF CAL0002118 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.7069 ORF CAL0002118 PMID: 21414038|CGD_REF: CAL0141808 homozygous diploid, classical genetics null BWP17 viable C. albicans orf19.707 ORF APG7 CAL0001705 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.707 ORF APG7 CAL0001705 PMID: 14663094|CGD_REF: CAL0080633 homozygous diploid, systematic mutation set (homozygous insertion mutants generated with URA3-ARG4-URA3 (UAU1) cassette) null BWP17 viable C. albicans orf19.7071 ORF FGR2 CAL0002137 PMID: 12773383|CGD_REF: CAL0087974 heterozygous diploid, classical genetics (haploinsufficient phenotype assay) null CAI-4 filamentous growth: decreased solid Spider medium heterozygous transposon insertion C. albicans orf19.7071 ORF FGR2 CAL0002137 PMID: 12773383|CGD_REF: CAL0087974 heterozygous diploid, classical genetics (haploinsufficient phenotype assay) null CAI-4 viable heterozygous transposon insertion C. albicans orf19.7071 ORF FGR2 CAL0002137 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.7071 ORF FGR2 CAL0002137 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.7071 ORF FGR2 CAL0002137 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.7071 ORF FGR2 CAL0002137 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.7071 ORF FGR2 CAL0002137 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.7072 ORF PEL1 CAL0002138 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.7074 ORF CAL0002142 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.7077 ORF CAL0002145 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.7077 ORF CAL0002145 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 invasive growth: decreased solid SLAD media C. albicans orf19.708 ORF CAL0001707 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.708 ORF CAL0001707 PMID: 21135205|CGD_REF: CAL0139967 heterozygous diploid, large-scale survey (large-scale identification of genes essential for virulence in mouse) repressible CAI-4 virulence: absent mouse intravenous infection C. albicans orf19.7080 ORF LEU2 CAL0002168 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.7080 ORF LEU2 CAL0002168 PMID: 2976118|CGD_REF: CAL0080668 unknown ploidy, classical genetics unspecified SC5314 auxotrophy leucine C. albicans orf19.7080 ORF LEU2 CAL0002168 PMID: 1879944|CGD_REF: CAL0091438 homozygous diploid, classical genetics null SC5314 auxotrophy leucine C. albicans orf19.7080 ORF LEU2 CAL0002168 PMID: 1879944|CGD_REF: CAL0091438 homozygous diploid, classical genetics null SC5314 virulence: decreased immunosuppressed mouse intravenous infection C. albicans orf19.7080 ORF LEU2 CAL0002168 PMID: 20737428|CGD_REF: CAL0126182 homozygous diploid, classical genetics null SC5314 auxotrophy leucine phenotype is also observed in the WO-1 background C. albicans orf19.7080 ORF LEU2 CAL0002168 PMID: 20737428|CGD_REF: CAL0126182 homozygous diploid, classical genetics null SC5314 viable phenotype is also observed in the WO-1 background C. albicans orf19.7081 ORF SPL1 CAL0002170 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.7083 ORF DCC1 CAL0002173 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.7084 ORF DFI1 CAL0002174 PMID: 20384695|CGD_REF: CAL0125373 homozygous diploid, classical genetics null BWP17 viable C. albicans orf19.7084 ORF DFI1 CAL0002174 PMID: 20384695|CGD_REF: CAL0125373 homozygous diploid, classical genetics null BWP17 resistance to chemicals: decreased Congo Red (200 micrograms/mL) C. albicans orf19.7084 ORF DFI1 CAL0002174 PMID: 20384695|CGD_REF: CAL0125373 homozygous diploid, classical genetics null BWP17 resistance to chemicals: decreased caspofungin (90 ng/ml) C. albicans orf19.7084 ORF DFI1 CAL0002174 PMID: 20384695|CGD_REF: CAL0125373 homozygous diploid, classical genetics null BWP17 protein activity: decreased Cek1p C. albicans orf19.7084 ORF DFI1 CAL0002174 PMID: 20384695|CGD_REF: CAL0125373 homozygous diploid, classical genetics null BWP17 virulence: decreased mouse intravenous infection C. albicans orf19.7084 ORF DFI1 CAL0002174 PMID: 20384695|CGD_REF: CAL0125373 heterozygous diploid, classical genetics null dfi1[G273,227L] (glycine 273 and glycine 277 were replaced with leucines, one copy of this allele was expressed in a dfi1/dfi1 background) BWP17 invasive growth: decreased embedded agar conditions defective for invasive filamentation C. albicans orf19.7084 ORF DFI1 CAL0002174 PMID: 20384695|CGD_REF: CAL0125373 homozygous diploid, classical genetics null BWP17 invasive growth: decreased embedded agar conditions defective for invasive filamentation C. albicans orf19.7086 ORF CAL0002176 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.7086 ORF CAL0002176 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.7086 ORF CAL0002176 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: abnormal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.7086 ORF CAL0002176 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.7086 ORF CAL0002176 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.7088 ORF CAL0002177 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.7089 ORF PMR1 CAL0002178 PMID: 15843378|CGD_REF: CAL0114265 homozygous diploid, classical genetics null CAI-4 filamentous growth: abnormal solid Spider medium filamentation is delayed C. albicans orf19.7089 ORF PMR1 CAL0002178 PMID: 15843378|CGD_REF: CAL0114265 homozygous diploid, classical genetics null Not recorded flocculation: increased yeast cells form small aggregates in liquid medium C. albicans orf19.7089 ORF PMR1 CAL0002178 PMID: 15843378|CGD_REF: CAL0114265 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased Hygromycin B C. albicans orf19.7089 ORF PMR1 CAL0002178 PMID: 15843378|CGD_REF: CAL0114265 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased Hygromycin B C. albicans orf19.7089 ORF PMR1 CAL0002178 PMID: 15843378|CGD_REF: CAL0114265 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased EGTA C. albicans orf19.7089 ORF PMR1 CAL0002178 PMID: 15843378|CGD_REF: CAL0114265 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased Calcofluor White C. albicans orf19.7089 ORF PMR1 CAL0002178 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.7089 ORF PMR1 CAL0002178 PMID: 15843378|CGD_REF: CAL0114265 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.7089 ORF PMR1 CAL0002178 PMID: 19154328|CGD_REF: CAL0122236 homozygous diploid, classical genetics null Other C. albicans hyphal growth: abnormal semisolid substrate abolished hyphal tip oscillation; shorter hyphal and cell length than wild type C. albicans orf19.7089 ORF PMR1 CAL0002178 PMID: 19154328|CGD_REF: CAL0122236 heterozygous diploid, classical genetics null Other C. albicans hyphal growth: abnormal semisolid substrate decreased hyphal tip oscillation, and decreased oscillatory wavelength C. albicans orf19.7089 ORF PMR1 CAL0002178 PMID: 15843378|CGD_REF: CAL0114265 homozygous diploid, classical genetics null Not recorded cell wall morphology: abnormal altered cell wall mannan content C. albicans orf19.7089 ORF PMR1 CAL0002178 PMID: 15843378|CGD_REF: CAL0114265 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased Congo Red C. albicans orf19.7089 ORF PMR1 CAL0002178 PMID: 15843378|CGD_REF: CAL0114265 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased Congo Red C. albicans orf19.7089 ORF PMR1 CAL0002178 PMID: 21059878|CGD_REF: CAL0139816 homozygous diploid, classical genetics null CAI-4 induction of host response: increased 6-8 week old female BALB/c mice increased levels of G-CSF, IL-6, and MIP-2 in the kidneys at 12 hrs post-infection C. albicans orf19.7089 ORF PMR1 CAL0002178 PMID: 20123707|CGD_REF: CAL0125018 homozygous diploid, classical genetics null CAI-4 resistance to phagocytosis: increased reduced rate of uptake by macrophages in vitro model of infection (bone marrow-derived macrophages) C. albicans orf19.7089 ORF PMR1 CAL0002178 PMID: 15843378|CGD_REF: CAL0114265 homozygous diploid, classical genetics null Not recorded virulence: decreased mouse intravenous infection C. albicans orf19.709 ORF PUP2 CAL0001709 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.7091 ORF CAL0002189 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.7092 ORF CAL0002191 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.7093 ORF HGT13 CAL0002193 PMID: 19383674|CGD_REF: CAL0122777 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.7094 ORF HGT12 CAL0002195 PMID: 17030998|CGD_REF: CAL0116776 homozygous diploid, classical genetics null BWP17 filamentous growth: normal solid Spider medium C. albicans orf19.7094 ORF HGT12 CAL0002195 PMID: 17030998|CGD_REF: CAL0116776 homozygous diploid, classical genetics null Not recorded utilization of carbon source: normal C. albicans orf19.7094 ORF HGT12 CAL0002195 PMID: 16084700|CGD_REF: CAL0114664 heterozygous diploid, classical genetics null Not recorded viable C. albicans orf19.7094 ORF HGT12 CAL0002195 PMID: 16084700|CGD_REF: CAL0114664 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.7094 ORF HGT12 CAL0002195 PMID: 17030998|CGD_REF: CAL0116776 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.7094 ORF HGT12 CAL0002195 PMID: 16084700|CGD_REF: CAL0114664 homozygous diploid, classical genetics null CAI-4 hyphal growth: abnormal macrophage engulfment or growth on solid serum-containing media forms abnormally short hyphae or no hyphae C. albicans orf19.7094 ORF HGT12 CAL0002195 PMID: 16084700|CGD_REF: CAL0114664 heterozygous diploid, classical genetics null CAI-4 hyphal growth: abnormal macrophage engulfment or growth on solid serum-containing media forms abnormally short hyphae; phenotype is intermediate between homozygous null mutant and wild type C. albicans orf19.7094 ORF HGT12 CAL0002195 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: decreased growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.7094 ORF HGT12 CAL0002195 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.7094 ORF HGT12 CAL0002195 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.7094 ORF HGT12 CAL0002195 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.7096 ORF CAL0002198 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.7096 ORF CAL0002198 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.7096 ORF CAL0002198 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.7096 ORF CAL0002198 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.7097 ORF CAL0002199 PMID: 19623926|CGD_REF: CAL0124054 heterozygous diploid, competitive growth (haploinsufficient phenotype assay, barcode deletion set) null SC5314 resistance to chemicals: decreased parnafungin C. albicans orf19.7097 ORF CAL0002199 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.7097 ORF CAL0002199 PMID: 19623926|CGD_REF: CAL0124054 heterozygous diploid, competitive growth (haploinsufficient phenotype assay, barcode deletion set) null SC5314 resistance to chemicals: decreased cordycepin C. albicans orf19.7098 ORF CAL0002200 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.7098 ORF CAL0002200 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.7098 ORF CAL0002200 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.7098 ORF CAL0002200 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.7098 ORF CAL0002200 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.7100 ORF CAL0002799 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 invasive growth: decreased solid SLAD media C. albicans orf19.7101 ORF CAL0002800 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.7105 ORF FAR1 CAL0002805 PMID: 18162580|CGD_REF: CAL0118948 homozygous diploid, classical genetics null Not recorded shmoo formation: decreased C. albicans orf19.7105 ORF FAR1 CAL0002805 PMID: 15814839|CGD_REF: CAL0114183 homozygous diploid, classical genetics null Not recorded viable no apparent phenotype C. albicans orf19.7105 ORF FAR1 CAL0002805 PMID: 15814839|CGD_REF: CAL0114183 heterozygous diploid, classical genetics null Not recorded viable C. albicans orf19.7105 ORF FAR1 CAL0002805 PMID: 18346117|CGD_REF: CAL0118920 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.7105 ORF FAR1 CAL0002805 PMID: 15814839|CGD_REF: CAL0114183 homozygous diploid, classical genetics null CAI-4 hyphal growth: normal serum-containing medium C. albicans orf19.7105 ORF FAR1 CAL0002805 PMID: 18162580|CGD_REF: CAL0118948 homozygous diploid, classical genetics null Not recorded mating efficiency: decreased severe reduction C. albicans orf19.7105 ORF FAR1 CAL0002805 PMID: 18346117|CGD_REF: CAL0118920 homozygous diploid, classical genetics null Not recorded mating efficiency: decreased severe reduction C. albicans orf19.7105 ORF FAR1 CAL0002805 PMID: 18162580|CGD_REF: CAL0118948 homozygous diploid, classical genetics null Not recorded phenotypic switching: normal C. albicans orf19.7105 ORF FAR1 CAL0002805 PMID: 18346117|CGD_REF: CAL0118920 homozygous diploid, classical genetics null Not recorded pheromone-induced cell cycle arrest: absent alpha factor does not arrest or undergo morphological changes C. albicans orf19.7105 ORF FAR1 CAL0002805 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.7105 ORF FAR1 CAL0002805 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.7105 ORF FAR1 CAL0002805 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.7105 ORF FAR1 CAL0002805 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.7107 ORF CAL0002809 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.7107 ORF CAL0002809 PMID: 21414038|CGD_REF: CAL0141808 homozygous diploid, classical genetics null BWP17 viable C. albicans orf19.7111 ORF CAL0002844 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.7111.1 ORF SOD3 CAL0006719 PMID: 19019164|CGD_REF: CAL0121070 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.7111.1 ORF SOD3 CAL0006719 PMID: 19019164|CGD_REF: CAL0121070 homozygous diploid, classical genetics null Not recorded interaction with host/environment: normal wild-type reactive oxygen species accumulation during response to macrophages in vitro model of infection C. albicans orf19.7111.1 ORF SOD3 CAL0006719 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient YPD medium C. albicans orf19.7111.1 ORF SOD3 CAL0006719 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient SC medium C. albicans orf19.7111.1 ORF SOD3 CAL0006719 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient YNB medium C. albicans orf19.7111.1 ORF SOD3 CAL0006719 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient SLAD medium C. albicans orf19.7112 ORF FRP2 CAL0002845 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.7112 ORF FRP2 CAL0002845 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.7112 ORF FRP2 CAL0002845 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.7112 ORF FRP2 CAL0002845 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.7112 ORF FRP2 CAL0002845 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.7114 ORF CSA1 CAL0002846 PMID: 10978273|CGD_REF: CAL0081429 homozygous diploid, classical genetics null CAI-4 viable no apparent growth defects under various laboratory conditions C. albicans orf19.7114 ORF CSA1 CAL0002846 PMID: 15306022|CGD_REF: CAL0082082 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.7114 ORF CSA1 CAL0002846 PMID: 17042757|CGD_REF: CAL0116848 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.7114 ORF CSA1 CAL0002846 PMID: 18765290|CGD_REF: CAL0119430 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.7114 ORF CSA1 CAL0002846 PMID: 10652105|CGD_REF: CAL0081083 homozygous diploid, classical genetics null csa1::CAT-URA3-CAT CAI-4 hyphal growth: normal C. albicans orf19.7114 ORF CSA1 CAL0002846 PMID: 10652105|CGD_REF: CAL0081083 heterozygous diploid, classical genetics null csa1::CAT-URA3-CAT CAI-4 viable C. albicans orf19.7114 ORF CSA1 CAL0002846 PMID: 10652105|CGD_REF: CAL0081083 homozygous diploid, classical genetics null csa1::CAT-URA3-CAT CAI-4 viable C. albicans orf19.7114 ORF CSA1 CAL0002846 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.7114 ORF CSA1 CAL0002846 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.7114 ORF CSA1 CAL0002846 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.7114 ORF CSA1 CAL0002846 PMID: 17042757|CGD_REF: CAL0116848 homozygous diploid, classical genetics null CAI-4 biofilm formation: abnormal C. albicans orf19.7114 ORF CSA1 CAL0002846 PMID: 23563485|CGD_REF: CAL0000158903 homozygous diploid, classical genetics null a/alpha csa1::FRT/csa1::FRT SC5314 biofilm formation: abnormal RPMI medium 29 degrees C with rocking for 48 hr mutants have reduced vertical orientation of hyphae, an abnormal extracellular matrix, complete penetrabity to Sypro Ruby and human PMNs and increased sensitivity to fluconazole C. albicans orf19.7114 ORF CSA1 CAL0002846 PMID: 23563485|CGD_REF: CAL0000158903 homozygous diploid, classical genetics repressible a/alpha csa1::FRT/csa1::FRT ADH1/adh1::pTET-CSA1::SATR SC5314 biofilm formation: abnormal RPMI medium 29 degrees C with rocking for 48 hr mutant has minor defects in vertical orientation of hyphae, complete permeability to Sypro Ruby and human PMNs and decreased fluconazole resistance C. albicans orf19.7114 ORF CSA1 CAL0002846 PMID: 23563485|CGD_REF: CAL0000158903 heterozygous diploid, classical genetics repressible a/a ADH1/adh1::pTET-CSA1::SATR (tet repressed) P37005 biofilm formation: abnormal RPMI medium 29 degrees C with rocking for 48 hr decreased Sypro Ruby and human PMN penetrability, decreased resistance to fluconazole C. albicans orf19.7114 ORF CSA1 CAL0002846 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.7115 ORF SAC7 CAL0002847 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.7115 ORF SAC7 CAL0002847 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.7115 ORF SAC7 CAL0002847 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.7115 ORF SAC7 CAL0002847 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.7115 ORF SAC7 CAL0002847 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.7118 ORF CAL0002851 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.7119 ORF RAD3 CAL0002854 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.712 ORF KIP1 CAL0001739 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.712 ORF KIP1 CAL0001739 PMID: 17573815|CGD_REF: CAL0118119 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.712 ORF KIP1 CAL0001739 PMID: 17573815|CGD_REF: CAL0118119 homozygous diploid, classical genetics null Not recorded cell cycle progression: abnormal transient cell cycle arrest C. albicans orf19.712 ORF KIP1 CAL0001739 PMID: 17573815|CGD_REF: CAL0118119 homozygous diploid, classical genetics null Not recorded cell shape: abnormal cells are elongated C. albicans orf19.7124 ORF RVS161 CAL0002888 PMID: 19596778|CGD_REF: CAL0123901 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased lithium chloride C. albicans orf19.7124 ORF RVS161 CAL0002888 PMID: 19596778|CGD_REF: CAL0123901 homozygous diploid, classical genetics null BWP17 filamentous growth: abnormal solid medium with 4% serum C. albicans orf19.7124 ORF RVS161 CAL0002888 PMID: 19596778|CGD_REF: CAL0123901 homozygous diploid, classical genetics null Not recorded toxin resistance: increased human salivary histatin 5 C. albicans orf19.7124 ORF RVS161 CAL0002888 PMID: 19596778|CGD_REF: CAL0123901 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased Calcofluor White C. albicans orf19.7124 ORF RVS161 CAL0002888 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.7124 ORF RVS161 CAL0002888 PMID: 19596778|CGD_REF: CAL0123901 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.7124 ORF RVS161 CAL0002888 PMID: 19596778|CGD_REF: CAL0123901 homozygous diploid, classical genetics null Not recorded bud morphology: abnormal buds are larger and rounder than wild type C. albicans orf19.7124 ORF RVS161 CAL0002888 PMID: 19596778|CGD_REF: CAL0123901 homozygous diploid, classical genetics null Not recorded budding pattern: abnormal bud site selection is more random than in wild type C. albicans orf19.7124 ORF RVS161 CAL0002888 PMID: 19596778|CGD_REF: CAL0123901 homozygous diploid, classical genetics null BWP17 hyphal growth: absent serum-containing medium at 37 deg C C. albicans orf19.7124 ORF RVS161 CAL0002888 PMID: 19596778|CGD_REF: CAL0123901 homozygous diploid, classical genetics null Not recorded oxidative stress resistance: decreased hydrogen peroxide C. albicans orf19.7124 ORF RVS161 CAL0002888 PMID: 19596778|CGD_REF: CAL0123901 homozygous diploid, classical genetics null Not recorded endocytosis: decreased the endocytic marker FM4-64 is not internalized C. albicans orf19.7124 ORF RVS161 CAL0002888 PMID: 19596778|CGD_REF: CAL0123901 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased Congo Red C. albicans orf19.7124 ORF RVS161 CAL0002888 PMID: 19596778|CGD_REF: CAL0123901 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased fluconazole C. albicans orf19.7124 ORF RVS161 CAL0002888 PMID: 19596778|CGD_REF: CAL0123901 homozygous diploid, classical genetics null Not recorded virulence: decreased mouse intravenous infection C. albicans orf19.7127 ORF TLO16 CAL0002892 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.7128 ORF SYS1 CAL0002894 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.7131 ORF CAL0002922 PMID: 19289605|CGD_REF: CAL0122500 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.7131 ORF CAL0002922 PMID: 19289605|CGD_REF: CAL0122500 homozygous diploid, classical genetics null Not recorded utilization of carbon source: absent acetic acid C. albicans orf19.7131 ORF CAL0002922 PMID: 19289605|CGD_REF: CAL0122500 homozygous diploid, classical genetics null Not recorded utilization of carbon source: absent oleic acid C. albicans orf19.7131 ORF CAL0002922 PMID: 19289605|CGD_REF: CAL0122500 homozygous diploid, classical genetics null Not recorded utilization of carbon source: absent ethanol C. albicans orf19.7136 ORF SPT6 CAL0002923 PMID: 12773383|CGD_REF: CAL0087974 heterozygous diploid, classical genetics (haploinsufficient phenotype assay) null CAI-4 filamentous growth: abnormal solid Spider medium or solid YEPD plus serum increased filamentous growth (solid YEPD plus serum) or decreased filamentous growth (solid Spider medium), or textured appearance (solid YEPD plus serum), depending on the allele; heterozygous transposon insertion C. albicans orf19.7136 ORF SPT6 CAL0002923 PMID: 12773383|CGD_REF: CAL0087974 heterozygous diploid, classical genetics (haploinsufficient phenotype assay) null CAI-4 viable heterozygous transposon insertion C. albicans orf19.7136 ORF SPT6 CAL0002923 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.7136 ORF SPT6 CAL0002923 PMID: 20060921|CGD_REF: CAL0124818 homozygous diploid, classical genetics null spt6::HIS1/spt6::LEU2 SC5314 viable C. albicans orf19.7136 ORF SPT6 CAL0002923 PMID: 20060921|CGD_REF: CAL0124818 homozygous diploid, classical genetics null spt6::HIS1/spt6::LEU2 SC5314 heat sensitivity: increased elevated temperature (37 deg) no growth C. albicans orf19.7136 ORF SPT6 CAL0002923 PMID: 20060921|CGD_REF: CAL0124818 homozygous diploid, classical genetics null spt6::HIS1/spt6::LEU2 SC5314 vegetative growth: decreased rate standard temperature (30 deg) very slow growth C. albicans orf19.7136 ORF SPT6 CAL0002923 PMID: 20060921|CGD_REF: CAL0124818 homozygous diploid, classical genetics null spt6::HIS1/spt6::LEU2 SC5314 hyphal growth: decreased no hyphal growth on solid media containing serum or on Spider media C. albicans orf19.714 ORF CAL0001741 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.7140 ORF CAL0002966 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.7141 ORF UFE1 CAL0002968 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.715 ORF CAL0001742 PMID: 19463063|CGD_REF: CAL0123630 homozygous diploid, systematic mutation set (split-marker transposon insertion strategy to disrupt both alleles) null BWP17 viable C. albicans orf19.715 ORF CAL0001742 PMID: 19463063|CGD_REF: CAL0123630 homozygous diploid, systematic mutation set (split-marker transposon insertion strategy to disrupt both alleles) null BWP17 virulence: normal Toll mutant D. melanogaster invasive infection insect infection C. albicans orf19.7150 ORF NRG1 CAL0002995 PMID: 20041210|CGD_REF: CAL0124764 homozygous diploid, systematic mutation set null SN152 resistance to chemicals: decreased fluconazole strongly sensitive C. albicans orf19.7150 ORF NRG1 CAL0002995 PMID: 15554973|CGD_REF: CAL0082478 homozygous diploid, classical genetics null BWP17 filamentous growth: abnormal constitutive filamentation C. albicans orf19.7150 ORF NRG1 CAL0002995 PMID: 12060662|CGD_REF: CAL0081313 homozygous diploid, classical genetics null Not recorded filamentous growth: abnormal YPD medium at 30 deg C constitutive filamentous growth C. albicans orf19.7150 ORF NRG1 CAL0002995 PMID: 18424510|CGD_REF: CAL0118975 homozygous diploid, classical genetics null CAI-4 filamentous growth: abnormal filamentation is insensitive to farnesol C. albicans orf19.7150 ORF NRG1 CAL0002995 PMID: 11532938|CGD_REF: CAL0080745 homozygous diploid, classical genetics null Not recorded filamentous growth: normal in response to serum, pH, or on solid Spider medium C. albicans orf19.7150 ORF NRG1 CAL0002995 PMID: 11532938|CGD_REF: CAL0080745 homozygous diploid, classical genetics null Not recorded filamentous growth: increased SLAD medium C. albicans orf19.7150 ORF NRG1 CAL0002995 PMID: 11532939|CGD_REF: CAL0081163 homozygous diploid, classical genetics null Not recorded filamentous growth: increased solid YPD, SD, or Spider media C. albicans orf19.7150 ORF NRG1 CAL0002995 PMID: 11532939|CGD_REF: CAL0081163 heterozygous diploid, classical genetics overexpression Not recorded germ tube formation: absent serum-containing, Spider, or cornmeal media, or heat treatment nrg1 is expressed constitutively C. albicans orf19.7150 ORF NRG1 CAL0002995 PMID: 17967861|CGD_REF: CAL0123285 heterozygous diploid, classical genetics repressible CAF2-1 germ tube formation: absent C. albicans orf19.7150 ORF NRG1 CAL0002995 PMID: 19057660|CGD_REF: CAL0121272 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased caspofungin filamentous cells appear to be more sensitive than yeast-form cells C. albicans orf19.7150 ORF NRG1 CAL0002995 PMID: 20041210|CGD_REF: CAL0124764 homozygous diploid, systematic mutation set null SN152 resistance to chemicals: decreased fenpropimorph strongly sensitive C. albicans orf19.7150 ORF NRG1 CAL0002995 PMID: 20041210|CGD_REF: CAL0124764 homozygous diploid, systematic mutation set null SN152 resistance to chemicals: decreased flucytosine strongly sensitive C. albicans orf19.7150 ORF NRG1 CAL0002995 PMID: 11532938|CGD_REF: CAL0080745 homozygous diploid, classical genetics null Not recorded vegetative growth: decreased rate C. albicans orf19.7150 ORF NRG1 CAL0002995 PMID: 11737641|CGD_REF: CAL0080636 homozygous diploid, classical genetics null Not recorded vegetative growth: decreased rate C. albicans orf19.7150 ORF NRG1 CAL0002995 PMID: 15964282|CGD_REF: CAL0114274 homozygous diploid, systematic mutation set (split-marker transposon insertion strategy to disrupt both alleles) null BWP17 viable C. albicans orf19.7150 ORF NRG1 CAL0002995 PMID: 11532938|CGD_REF: CAL0080745 heterozygous diploid, classical genetics null Not recorded viable C. albicans orf19.7150 ORF NRG1 CAL0002995 PMID: 11532938|CGD_REF: CAL0080745 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.7150 ORF NRG1 CAL0002995 PMID: 11532939|CGD_REF: CAL0081163 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.7150 ORF NRG1 CAL0002995 PMID: 11737641|CGD_REF: CAL0080636 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.7150 ORF NRG1 CAL0002995 PMID: 12060662|CGD_REF: CAL0081313 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.7150 ORF NRG1 CAL0002995 PMID: 14555488|CGD_REF: CAL0081607 heterozygous diploid, classical genetics overexpression Not recorded viable C. albicans orf19.7150 ORF NRG1 CAL0002995 PMID: 15554973|CGD_REF: CAL0082478 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.7150 ORF NRG1 CAL0002995 PMID: 20041210|CGD_REF: CAL0124764 homozygous diploid, systematic mutation set null SN152 resistance to chemicals: decreased rapamycin strongly sensitive C. albicans orf19.7150 ORF NRG1 CAL0002995 PMID: 15964282|CGD_REF: CAL0114274 homozygous diploid, systematic mutation set (split-marker transposon insertion strategy to disrupt both alleles) null BWP17 biofilm formation: normal C. albicans orf19.7150 ORF NRG1 CAL0002995 PMID: 14555488|CGD_REF: CAL0081607 heterozygous diploid, classical genetics overexpression CAF2-1 hyphal growth: absent various media C. albicans orf19.7150 ORF NRG1 CAL0002995 PMID: 16087738|CGD_REF: CAL0114510 heterozygous diploid, classical genetics misexpression CAI-4 hyphal growth: absent liquid hyphal-inducing media C. albicans orf19.7150 ORF NRG1 CAL0002995 PMID: 11532938|CGD_REF: CAL0080745 homozygous diploid, classical genetics null Not recorded invasive growth: increased agar invasion is constitutive C. albicans orf19.7150 ORF NRG1 CAL0002995 PMID: 20041210|CGD_REF: CAL0124764 homozygous diploid, systematic mutation set null SN152 invasive growth: increased SD or YEPD media at 30 deg C strongly increased C. albicans orf19.7150 ORF NRG1 CAL0002995 PMID: 11532938|CGD_REF: CAL0080745 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased ethanol also displays sensitivity to carbon limitation C. albicans orf19.7150 ORF NRG1 CAL0002995 PMID: 11737641|CGD_REF: CAL0080636 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased ethanol C. albicans orf19.7150 ORF NRG1 CAL0002995 PMID: 11532938|CGD_REF: CAL0080745 homozygous diploid, classical genetics null Not recorded oxidative stress resistance: decreased hydrogen peroxide C. albicans orf19.7150 ORF NRG1 CAL0002995 PMID: 11737641|CGD_REF: CAL0080636 homozygous diploid, classical genetics null Not recorded oxidative stress resistance: decreased hydrogen peroxide C. albicans orf19.7150 ORF NRG1 CAL0002995 PMID: 15659176|CGD_REF: CAL0103920 homozygous diploid, classical genetics null Not recorded chlamydospore formation: abnormal solid Staib agar mutant forms chlamydospores under conditions where C. dubliniensis normally forms chlamydospores and C. albicans normally does not C. albicans orf19.7150 ORF NRG1 CAL0002995 PMID: 11532938|CGD_REF: CAL0080745 homozygous diploid, classical genetics null Not recorded chlamydospore formation: normal no delay in chlamydospore induction C. albicans orf19.7150 ORF NRG1 CAL0002995 PMID: 11532938|CGD_REF: CAL0080745 homozygous diploid, classical genetics null Not recorded colony appearance: abnormal solid YPD at 25 deg C wrinkled colonies C. albicans orf19.7150 ORF NRG1 CAL0002995 PMID: 20041210|CGD_REF: CAL0124764 homozygous diploid, systematic mutation set null SN152 colony appearance: abnormal multiple different media including YEPD with or without serum, Spider, Lee's, blood agar; temperatures from 30-42 deg C strongly increased colony fuzziness and/or peripheral filamentation C. albicans orf19.7150 ORF NRG1 CAL0002995 PMID: 20041210|CGD_REF: CAL0124764 homozygous diploid, systematic mutation set null SN152 colony color: abnormal CHROMagar medium at 30 deg C darker than normal C. albicans orf19.7150 ORF NRG1 CAL0002995 PMID: 11532938|CGD_REF: CAL0080745 homozygous diploid, classical genetics null Not recorded pseudohyphal growth: increased pseudohyphal growth under conditions favoring yeast-form growth of wild type C. albicans orf19.7150 ORF NRG1 CAL0002995 PMID: 11532938|CGD_REF: CAL0080745 heterozygous diploid, classical genetics repressible Not recorded pseudohyphal growth: increased pseudohyphal growth under conditions favoring yeast-form growth of wild type C. albicans orf19.7150 ORF NRG1 CAL0002995 PMID: 18424510|CGD_REF: CAL0118975 homozygous diploid, classical genetics null Not recorded chemical compound accumulation: increased farnesol C. albicans orf19.7150 ORF NRG1 CAL0002995 PMID: 20709787|CGD_REF: CAL0126049 unknown ploidy, classical genetics overexpression NRG1(tet) (no doxicyclin) CAI-8 biofilm formation: abnormal only yeast and pseudohyphal cells were found attached to the substrate, no hyphae present C. albicans orf19.7150 ORF NRG1 CAL0002995 PMID: 21512583|CGD_REF: CAL0141906 homozygous diploid, classical genetics null SC5314 RNA accumulation: increased under conditions which favor yeast growth of wild type cells (YPD, 30 degrees C), EED1/DEF1 was significantly up-regulated in nrg1 cells as compared to the wild type EED1/DEF1 mRNA C. albicans orf19.7150 ORF NRG1 CAL0002995 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: increased growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.7150 ORF NRG1 CAL0002995 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: abnormal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.7150 ORF NRG1 CAL0002995 PMID: 19666778|CGD_REF: CAL0123941 homozygous diploid, classical genetics null Not recorded virulence: decreased C. elegans infection C. albicans orf19.7150 ORF NRG1 CAL0002995 PMID: 17967861|CGD_REF: CAL0123285 aneuploid, classical genetics overexpression Not recorded virulence: decreased B-cell deficient, nude, SCID, and C5-deficient mice immunosuppressed mouse intravenous infection C. albicans orf19.7150 ORF NRG1 CAL0002995 PMID: 17967861|CGD_REF: CAL0123285 aneuploid, classical genetics overexpression Not recorded virulence: normal severely immunosuppressed (cyclophosphamide-cortisone acetate-treated) mice immunosuppressed mouse intravenous infection C. albicans orf19.7150 ORF NRG1 CAL0002995 PMID: 16518764|CGD_REF: CAL0115737 heterozygous diploid, classical genetics overexpression Not recorded virulence: decreased Toll (T1)-deficient Drosophila melanogaster conditional overexpression (doxycycline-repressible) insect infection C. albicans orf19.7150 ORF NRG1 CAL0002995 PMID: 14555488|CGD_REF: CAL0081607 heterozygous diploid, classical genetics overexpression Not recorded virulence: absent avirulent, despite organ colonization mouse intravenous infection C. albicans orf19.7150 ORF NRG1 CAL0002995 PMID: 17005810|CGD_REF: CAL0116695 heterozygous diploid, classical genetics overexpression Not recorded virulence: decreased induction of overexpression 24-48 hours post-infection inhibits filamentation and reduces virulence (doxycycline-regulated NRG1 expression construct) mouse intravenous infection C. albicans orf19.7150 ORF NRG1 CAL0002995 PMID: 19144791|CGD_REF: CAL0122173 heterozygous diploid, classical genetics repressible Not recorded virulence: abnormal infection with strain containing tetracycline-regulated tetNRG1 construct (no drug, yeast-form cells) causes resistance to subsequent challenge with a wild-type strain mouse intravenous infection C. albicans orf19.7150 ORF NRG1 CAL0002995 PMID: 11532938|CGD_REF: CAL0080745 homozygous diploid, classical genetics null Not recorded virulence: decreased mouse intravenous infection C. albicans orf19.7150 ORF NRG1 CAL0002995 PMID: 11532939|CGD_REF: CAL0081163 homozygous diploid, classical genetics null Not recorded virulence: absent mouse intravenous infection C. albicans orf19.7150 ORF NRG1 CAL0002995 PMID: 17967861|CGD_REF: CAL0123285 aneuploid, classical genetics overexpression Not recorded virulence: decreased mouse intravenous infection C. albicans orf19.7150 ORF NRG1 CAL0002995 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: decreased rate liquid synthetic complete medium C. albicans orf19.7150 ORF NRG1 CAL0002995 PMID: 20232156|CGD_REF: CAL0125119 heterozygous diploid, classical genetics overexpression tet-NRG1 (overexpression in the absence of doxycyclin) CAF2-1 filamentous growth: absent alkaline medium (pH 8) without doxycycline (derepressing conditions) C. albicans orf19.7150 ORF NRG1 CAL0002995 PMID: 20232156|CGD_REF: CAL0125119 heterozygous diploid, classical genetics overexpression tet-NRG1 (overexpression in the absence of doxycyclin) CAF2-1 filamentous growth: absent RPMI-1640 medium or GlcNAc medium without doxycycline (derepressing conditions) C. albicans orf19.7150 ORF NRG1 CAL0002995 PMID: 20232156|CGD_REF: CAL0125119 heterozygous diploid, classical genetics overexpression tet-NRG1 (overexpression in the absence of doxycyclin) CAF2-1 filamentous growth: absent solid Spider medium without doxycycline (derepressing conditions) C. albicans orf19.7150 ORF NRG1 CAL0002995 PMID: 20232156|CGD_REF: CAL0125119 heterozygous diploid, classical genetics overexpression tet-NRG1 (overexpression in the absence of doxycyclin) CAF2-1 invasive growth: decreased embedded in solid medium without doxycycline (derepressing conditions) C. albicans orf19.7150 ORF NRG1 CAL0002995 PMID: 19197361|CGD_REF: CAL0122318 homozygous diploid, classical genetics null SC5314 resistance to chemicals: decreased rapamycin (2 nM) C. albicans orf19.7150 ORF NRG1 CAL0002995 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.7152 ORF CAL0002998 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.7152 ORF CAL0002998 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient YPD medium C. albicans orf19.7154 ORF UTP18 CAL0003002 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.7156 ORF FAA2-3 CAL0003004 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.7158 ORF CAL0003006 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.716 ORF CAL0001743 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.716 ORF CAL0001743 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.716 ORF CAL0001743 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.716 ORF CAL0001743 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.7161 ORF SUI3 CAL0003036 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.7164 ORF CAL0003042 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.7165 ORF MED9 CAL0003045 PMID: 23873866|CGD_REF: CAL0000172574 homozygous diploid, classical genetics null SN152 phenotypic switching: abnormal C. albicans orf19.717 ORF HSP60 CAL0001744 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.717 ORF HSP60 CAL0001744 PMID: 21209325|CGD_REF: CAL0140079 heterozygous diploid, classical genetics reduction of function hsp60/HSP60-K324R (sumoylation site mutant) BWP17 cell shape: abnormal C. albicans orf19.717 ORF HSP60 CAL0001744 PMID: 21209325|CGD_REF: CAL0140079 heterozygous diploid, classical genetics reduction of function hsp60/HSP60-K324R (sumoylation site mutant) BWP17 heat sensitivity: increased 30-42 degree C heat shock in the presence of the respiratory inhibitor Antimycin A no difference was observed in the absence of Antimycin A C. albicans orf19.717 ORF HSP60 CAL0001744 PMID: 21209325|CGD_REF: CAL0140079 heterozygous diploid, classical genetics null hsp60/HSP60 (sumoylation site mutant) BWP17 heat sensitivity: increased 30-42 degree C heat shock in the presence of the respiratory inhibitor Antimycin A no difference was observed in the absence of Antimycin A C. albicans orf19.717 ORF HSP60 CAL0001744 PMID: 21209325|CGD_REF: CAL0140079 heterozygous diploid, classical genetics reduction of function hsp60/HSP60-K324R (sumoylation site mutant) BWP17 colony appearance: abnormal wrinkled colony morphology C. albicans orf19.7170 ORF CAL0003076 PMID: 24610660|CGD_REF: CAL0000173793 homozygous diploid, classical genetics null BWP17 viable C. albicans orf19.7175 ORF HLJ1 CAL0003087 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.7176 ORF NPT1 CAL0003088 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.7177 ORF KAP120 CAL0003089 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, competitive growth (haploinsufficient phenotype assay, barcode deletion set) null SC5314 resistance to chemicals: decreased cytochalasin D C. albicans orf19.7177 ORF KAP120 CAL0003089 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.7178 ORF PRE5 CAL0003090 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.718 ORF RRN11 CAL0001746 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.718 ORF RRN11 CAL0001746 PMID: 15964282|CGD_REF: CAL0114274 homozygous diploid, systematic mutation set (split-marker transposon insertion strategy to disrupt both alleles) null BWP17 inviable homozygous null mutant strain could not be recovered, suggesting that the gene is essential under the selection conditions C. albicans orf19.7185 ORF CAL0003130 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.7185 ORF CAL0003130 PMID: 23075292|CGD_REF: CAL0000158032 homozygous diploid, classical genetics null SC5314 viable C. albicans orf19.7186 ORF CLB4 CAL0003132 PMID: 15888543|CGD_REF: CAL0114307 heterozygous diploid, classical genetics overexpression Not recorded germ tube formation: decreased serum-containing medium fewer and shorter germ tubes observed C. albicans orf19.7186 ORF CLB4 CAL0003132 PMID: 15888543|CGD_REF: CAL0114307 homozygous diploid, classical genetics null Not recorded germ tube formation: abnormal serum-containing medium germ tubes are wider than normal C. albicans orf19.7186 ORF CLB4 CAL0003132 PMID: 15888543|CGD_REF: CAL0114307 heterozygous diploid, classical genetics repressible Not recorded germ tube formation: abnormal serum-containing medium germ tubes are wider than normal C. albicans orf19.7186 ORF CLB4 CAL0003132 PMID: 15888543|CGD_REF: CAL0114307 heterozygous diploid, classical genetics null Not recorded viable C. albicans orf19.7186 ORF CLB4 CAL0003132 PMID: 15888543|CGD_REF: CAL0114307 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.7186 ORF CLB4 CAL0003132 PMID: 19458191|CGD_REF: CAL0123591 homozygous diploid, classical genetics null Not recorded RNA accumulation: decreased total RNA C. albicans orf19.7186 ORF CLB4 CAL0003132 PMID: 15888543|CGD_REF: CAL0114307 heterozygous diploid, classical genetics dominant negative Not recorded inviable mutant lacking the destruction box shows dominant inviability; terminal phenotype shows branching, elongated buds (increased polarized growth without cytokinesis) C. albicans orf19.7186 ORF CLB4 CAL0003132 PMID: 15888543|CGD_REF: CAL0114307 homozygous diploid, classical genetics null BWP17 pseudohyphal growth: abnormal constitutively pseudohyphal C. albicans orf19.7186 ORF CLB4 CAL0003132 PMID: 15888543|CGD_REF: CAL0114307 heterozygous diploid, classical genetics repressible BWP17 pseudohyphal growth: abnormal constitutively pseudohyphal C. albicans orf19.7186 ORF CLB4 CAL0003132 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: decreased growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.7186 ORF CLB4 CAL0003132 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: abnormal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.7186 ORF CLB4 CAL0003132 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: decreased rate liquid synthetic complete medium C. albicans orf19.7186 ORF CLB4 CAL0003132 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.7188 ORF RPP1B CAL0006682 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.7190 ORF OGG1 CAL0003150 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.7190 ORF OGG1 CAL0003150 PMID: 18667577|CGD_REF: CAL0119361 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.7193 ORF CAL0003158 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient SLAD medium C. albicans orf19.7194 ORF CAL0003161 PMID: 14663094|CGD_REF: CAL0080633 homozygous diploid, systematic mutation set (homozygous insertion mutants generated with URA3-ARG4-URA3 (UAU1) cassette) null BWP17 viable C. albicans orf19.7194 ORF CAL0003161 PMID: 17645752|CGD_REF: CAL0119305 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.7194 ORF CAL0003161 PMID: 17645752|CGD_REF: CAL0119305 homozygous diploid, classical genetics null Not recorded virulence: decreased reconstituted human epithelium decreased capacity to cause tissue damage ex vivo model of infection C. albicans orf19.7195 ORF RAD6 CAL0003164 PMID: 10712706|CGD_REF: CAL0081059 heterozygous diploid, classical genetics overexpression MET3-RAD6/rad6 CAI-4 germ tube formation: delayed serum-containing medium C. albicans orf19.7195 ORF RAD6 CAL0003164 PMID: 10712706|CGD_REF: CAL0081059 heterozygous diploid, classical genetics repressible MET3-RAD6/rad6 CAI-4 pseudohyphal growth: increased C. albicans orf19.7195 ORF RAD6 CAL0003164 PMID: 10712706|CGD_REF: CAL0081059 heterozygous diploid, classical genetics repressible MET3-RAD6/rad6 CAI-4 UV resistance: decreased C. albicans orf19.7195 ORF RAD6 CAL0003164 PMID: 10712706|CGD_REF: CAL0081059 heterozygous diploid, classical genetics repressible MET3-RAD6/rad6 CAI-4 vegetative growth: decreased rate C. albicans orf19.7195 ORF RAD6 CAL0003164 PMID: 10712706|CGD_REF: CAL0081059 homozygous diploid, classical genetics null rad6::hisG-URA3-hisG CAI-4 inviable homozygous null mutant strain could not be recovered, suggesting that the gene is essential under the selection conditions C. albicans orf19.7196 ORF CAL0003166 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.7196 ORF CAL0003166 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.7196 ORF CAL0003166 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.7196 ORF CAL0003166 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.7197 ORF CAL0003167 PMID: 19623926|CGD_REF: CAL0124054 heterozygous diploid, competitive growth (haploinsufficient phenotype assay, barcode deletion set) null SC5314 resistance to chemicals: increased parnafungin C. albicans orf19.7197 ORF CAL0003167 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.7197 ORF CAL0003167 PMID: 21135205|CGD_REF: CAL0139967 heterozygous diploid, large-scale survey (large-scale identification of genes essential for virulence in mouse) repressible CAI-4 virulence: absent mouse intravenous infection C. albicans orf19.7201 ORF SLA2 CAL0003735 PMID: 16896210|CGD_REF: CAL0116431 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased Calcofluor White C. albicans orf19.7201 ORF SLA2 CAL0003735 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.7201 ORF SLA2 CAL0003735 PMID: 12524333|CGD_REF: CAL0080691 homozygous diploid, systematic mutation set (homozygous insertion mutants generated with URA3-ARG4-URA3 (UAU1) cassette) null BWP17 viable C. albicans orf19.7201 ORF SLA2 CAL0003735 PMID: 14663094|CGD_REF: CAL0080633 homozygous diploid, systematic mutation set (homozygous insertion mutants generated with URA3-ARG4-URA3 (UAU1) cassette) null BWP17 viable C. albicans orf19.7201 ORF SLA2 CAL0003735 PMID: 11158313|CGD_REF: CAL0081455 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.7201 ORF SLA2 CAL0003735 PMID: 19778960|CGD_REF: CAL0124332 homozygous diploid, classical genetics null BWP17 viable C. albicans orf19.7201 ORF SLA2 CAL0003735 PMID: 19778960|CGD_REF: CAL0124332 homozygous diploid, classical genetics null BWP17 heat sensitivity: increased elevated temperature (37 or 42 deg C) C. albicans orf19.7201 ORF SLA2 CAL0003735 PMID: 19778960|CGD_REF: CAL0124332 homozygous diploid, classical genetics null BWP17 cell size: abnormal permissive temperature (30 deg C) cells are larger and rounder than wild type C. albicans orf19.7201 ORF SLA2 CAL0003735 PMID: 19778960|CGD_REF: CAL0124332 homozygous diploid, classical genetics null BWP17 cell cycle progression through the G2/M phase transition: delayed permissive temperature (30 deg C) C. albicans orf19.7201 ORF SLA2 CAL0003735 PMID: 19778960|CGD_REF: CAL0124332 homozygous diploid, classical genetics null BWP17 actin cytoskeleton morphology: abnormal abnormal actin patch morphology and localization, fewer and randomly oriented actin cables C. albicans orf19.7201 ORF SLA2 CAL0003735 PMID: 16896210|CGD_REF: CAL0116431 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased sodium dodecyl sulfate C. albicans orf19.7201 ORF SLA2 CAL0003735 PMID: 12524333|CGD_REF: CAL0080691 homozygous diploid, systematic mutation set (homozygous insertion mutants generated with URA3-ARG4-URA3 (UAU1) cassette) null BWP17 hyphal growth: abnormal defective alkaline pH-induced hyphal growth C. albicans orf19.7201 ORF SLA2 CAL0003735 PMID: 11158313|CGD_REF: CAL0081455 homozygous diploid, classical genetics null Not recorded hyphal growth: absent milk-Tween agar or RPMI medium containing 20% fetal calf serum C. albicans orf19.7201 ORF SLA2 CAL0003735 PMID: 16896210|CGD_REF: CAL0116431 homozygous diploid, classical genetics null Not recorded chitin deposition: abnormal C. albicans orf19.7201 ORF SLA2 CAL0003735 PMID: 16896210|CGD_REF: CAL0116431 homozygous diploid, classical genetics null Not recorded endocytosis: decreased defective fluid-phase endocytosis C. albicans orf19.7201 ORF SLA2 CAL0003735 PMID: 18466294|CGD_REF: CAL0119004 homozygous diploid, classical genetics null Not recorded utilization of iron source: absent hemoglobin C. albicans orf19.7201 ORF SLA2 CAL0003735 PMID: 17241762|CGD_REF: CAL0117323 homozygous diploid, classical genetics null Not recorded virulence: decreased mild defect mouse corneal infection C. albicans orf19.7206 ORF OCA6 CAL0003740 PMID: 18708562|CGD_REF: CAL0119375 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.7206 ORF OCA6 CAL0003740 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.7206 ORF OCA6 CAL0003740 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.7206 ORF OCA6 CAL0003740 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.7206 ORF OCA6 CAL0003740 PMID: 18708562|CGD_REF: CAL0119375 homozygous diploid, classical genetics null Not recorded virulence: decreased insect infection C. albicans orf19.7206 ORF OCA6 CAL0003740 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.7207 ORF DOA4 CAL0003741 PMID: 14663094|CGD_REF: CAL0080633 homozygous diploid, systematic mutation set (homozygous insertion mutants generated with URA3-ARG4-URA3 (UAU1) cassette) null BWP17 viable C. albicans orf19.7207 ORF DOA4 CAL0003741 PMID: 23856128|CGD_REF: CAL0000172540 homozygous diploid, classical genetics null BWP17 resistance to chemicals: decreased propolis C. albicans orf19.7207 ORF DOA4 CAL0003741 PMID: 20581294|CGD_REF: CAL0125802 homozygous diploid, classical genetics null BWP17 metal resistance: decreased lithium chloride (150 mM) YPD plus 150 mM lithium chloride C. albicans orf19.7208 ORF CSK1 CAL0003743 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.7208 ORF CSK1 CAL0003743 PMID: 14663094|CGD_REF: CAL0080633 homozygous diploid, systematic mutation set (homozygous insertion mutants generated with URA3-ARG4-URA3 (UAU1) cassette) null BWP17 viable C. albicans orf19.7208 ORF CSK1 CAL0003743 PMID: 12549007|CGD_REF: CAL0080982 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.7208 ORF CSK1 CAL0003743 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.7208 ORF CSK1 CAL0003743 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.7208 ORF CSK1 CAL0003743 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.7208 ORF CSK1 CAL0003743 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.721 ORF CAL0001772 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.721 ORF CAL0001772 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 invasive growth: decreased solid SLAD media C. albicans orf19.7210 ORF CAL0003765 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.7212 ORF CAL0003766 PMID: 20141603|CGD_REF: CAL0124951 homozygous diploid, systematic mutation set (homozygous insertion mutants generated with URA3-ARG4-URA3 (UAU1) cassette) null BWP17 colony appearance: abnormal 10% serum or Spider media at 37 deg C colonies are smoother than wild type but mutant is able to form true hyphae under liquid inducing conditions C. albicans orf19.7212 ORF CAL0003766 PMID: 20141603|CGD_REF: CAL0124951 homozygous diploid, systematic mutation set (homozygous insertion mutants generated with URA3-ARG4-URA3 (UAU1) cassette) null BWP17 viable C. albicans orf19.7214 ORF CAL0003768 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.7214 ORF CAL0003768 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.7214 ORF CAL0003768 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.7214 ORF CAL0003768 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.7215 ORF CAL0003770 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.7215 ORF CAL0003770 PMID: 21135205|CGD_REF: CAL0139967 heterozygous diploid, large-scale survey (large-scale identification of genes essential for virulence in mouse) repressible CAI-4 virulence: absent mouse intravenous infection C. albicans orf19.7216 ORF YPT52 CAL0003771 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.7216 ORF YPT52 CAL0003771 PMID: 23709183|CGD_REF: CAL0000172370 homozygous diploid, classical genetics null BWP17 viable C. albicans orf19.7216 ORF YPT52 CAL0003771 PMID: 23709183|CGD_REF: CAL0000172370 homozygous diploid, classical genetics null BWP17 vacuolar morphology: abnormal C. albicans orf19.7217 ORF RPL4B CAL0003773 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.7218 ORF RBE1 CAL0003775 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.7218 ORF RBE1 CAL0003775 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.7218 ORF RBE1 CAL0003775 PMID: 23136884|CGD_REF: CAL0000158105 homozygous diploid, classical genetics null rbe1::FRT/rbe1::FRT SC5314 virulence: decreased single deletion of RBE1 or RBT4 in a clinical C. albicans isolate resulted in moderate but significant attenuation in virulence in a mouse model for disseminated candidiasis. Virulence is strongly attenuated in a rbe1/rbt4 double mutant; the double deletion strain also showed increased sensitivity to attack by polymorphonuclear leukocytes mouse intravenous infection C. albicans orf19.7218 ORF RBE1 CAL0003775 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.7218 ORF RBE1 CAL0003775 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.7219 ORF FTR1 CAL0003776 PMID: 18503007|CGD_REF: CAL0119016 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased iron chelators pH 6 severe growth defect in the presence of iron chelator bathophenanthroline disulphonate C. albicans orf19.7219 ORF FTR1 CAL0003776 PMID: 16113264|CGD_REF: CAL0114585 heterozygous diploid, classical genetics null Not recorded small molecule transport: normal wild-type growth using diferric transferrin iron source C. albicans orf19.7219 ORF FTR1 CAL0003776 PMID: 19023418|CGD_REF: CAL0121072 homozygous diploid, classical genetics null Not recorded utilization of iron source: absent ferritin C. albicans orf19.7219 ORF FTR1 CAL0003776 PMID: 10807578|CGD_REF: CAL0081311 homozygous diploid, classical genetics null SC5314 utilization of iron source: abnormal abolished high-affinity iron uptake and growth under iron-depletion conditions C. albicans orf19.7219 ORF FTR1 CAL0003776 PMID: 16113264|CGD_REF: CAL0114585 homozygous diploid, classical genetics null Not recorded utilization of iron source: decreased decreased iron uptake from diferric transferrin or ferrous ascorbate iron source; slow growth using diferric transferrin iron source; lack of growth under low pH, iron starvation conditions C. albicans orf19.7219 ORF FTR1 CAL0003776 PMID: 18503007|CGD_REF: CAL0119016 homozygous diploid, classical genetics null Not recorded vegetative growth: normal rate solid YPG medium C. albicans orf19.7219 ORF FTR1 CAL0003776 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.7219 ORF FTR1 CAL0003776 PMID: 10807578|CGD_REF: CAL0081311 homozygous diploid, classical genetics null SC5314 viable C. albicans orf19.7219 ORF FTR1 CAL0003776 PMID: 16954314|CGD_REF: CAL0116835 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased fluconazole reversible by iron supplementation C. albicans orf19.7219 ORF FTR1 CAL0003776 PMID: 19023418|CGD_REF: CAL0121072 homozygous diploid, classical genetics null Not recorded virulence: decreased oral epithelial cells decreased capacity to damage cells in vitro model of infection C. albicans orf19.7219 ORF FTR1 CAL0003776 PMID: 10807578|CGD_REF: CAL0081311 homozygous diploid, classical genetics null SC5314 virulence: decreased abolished kidney colonization mouse intravenous infection C. albicans orf19.7219 ORF FTR1 CAL0003776 PMID: 10807578|CGD_REF: CAL0081311 homozygous diploid, classical genetics null SC5314 virulence: absent mouse intravenous infection C. albicans orf19.7221 ORF SET3 CAL0003800 PMID: 12773383|CGD_REF: CAL0087974 heterozygous diploid, classical genetics (haploinsufficient phenotype assay) null CAI-4 filamentous growth: abnormal solid Spider medium or solid YEPD plus serum increased or decreased filamentous growth, depending on the allele and medium; heterozygous transposon insertions C. albicans orf19.7221 ORF SET3 CAL0003800 PMID: 12773383|CGD_REF: CAL0087974 heterozygous diploid, classical genetics (haploinsufficient phenotype assay) null CAI-4 viable heterozygous transposon insertion C. albicans orf19.7221 ORF SET3 CAL0003800 PMID: 19555456|CGD_REF: CAL0123821 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.7221 ORF SET3 CAL0003800 PMID: 19555456|CGD_REF: CAL0123821 homozygous diploid, classical genetics null Not recorded phenotypic switching: decreased MTLa/MTLa background white-to-opaque switching C. albicans orf19.7221 ORF SET3 CAL0003800 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.7221 ORF SET3 CAL0003800 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: abnormal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.7221 ORF SET3 CAL0003800 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.7221 ORF SET3 CAL0003800 PMID: 20485517|CGD_REF: CAL0125674 homozygous diploid, classical genetics null SN152 filamentous growth: abnormal MTL a/a opaque cells, Lee's agar plates wrinkled colonies composed of mostly pseudohyphal structures C. albicans orf19.7221 ORF SET3 CAL0003800 PMID: 20485517|CGD_REF: CAL0125674 homozygous diploid, classical genetics null SN152 colony appearance: abnormal MTL a/a opaque cells, Lee's agar plates wrinkled colonies composed of mostly pseudohyphal structures C. albicans orf19.7221 ORF SET3 CAL0003800 PMID: 20485517|CGD_REF: CAL0125674 homozygous diploid, classical genetics null SN152 filamentous growth: increased MTL a/alpha cells, YPD medium, elevated temperature wrinkled colonies composed of mostly true hyphae C. albicans orf19.7221 ORF SET3 CAL0003800 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.7222 ORF PAM16 CAL0003801 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.7223 ORF CAL0003802 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.7224 ORF CAL0003803 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.7224 ORF CAL0003803 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.7224 ORF CAL0003803 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: abnormal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.7224 ORF CAL0003803 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.7224 ORF CAL0003803 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.7227 ORF CAL0003807 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, competitive growth (haploinsufficient phenotype assay, barcode deletion set) null SC5314 resistance to chemicals: decreased ergosterol analogs (ECC69 and/or ECC1384) C. albicans orf19.7227 ORF CAL0003807 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.7227 ORF CAL0003807 PMID: 20141603|CGD_REF: CAL0124951 homozygous diploid, systematic mutation set (homozygous insertion mutants generated with URA3-ARG4-URA3 (UAU1) cassette) null BWP17 colony appearance: abnormal 10% serum or Spider media at 37 deg C colonies are smoother than wild type but mutant is able to form true hyphae under liquid inducing conditions C. albicans orf19.7227 ORF CAL0003807 PMID: 20141603|CGD_REF: CAL0124951 homozygous diploid, systematic mutation set (homozygous insertion mutants generated with URA3-ARG4-URA3 (UAU1) cassette) null BWP17 viable C. albicans orf19.7228 ORF CAL0003808 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.7228 ORF CAL0003808 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.7228 ORF CAL0003808 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.7228 ORF CAL0003808 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.7228 ORF CAL0003808 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.7229 ORF IML2 CAL0003810 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient SC medium C. albicans orf19.723 ORF BCR1 CAL0001773 PMID: 20041210|CGD_REF: CAL0124764 homozygous diploid, systematic mutation set null SN152 resistance to chemicals: increased fluconazole strongly resistant C. albicans orf19.723 ORF BCR1 CAL0001773 PMID: 19779551|CGD_REF: CAL0124331 homozygous diploid, classical genetics null CAI-4 filamentous growth: abnormal solid Spider medium C. albicans orf19.723 ORF BCR1 CAL0001773 PMID: 17555439|CGD_REF: CAL0117968 homozygous diploid, classical genetics null Not recorded survival rate in stationary phase: decreased C. albicans orf19.723 ORF BCR1 CAL0001773 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.723 ORF BCR1 CAL0001773 PMID: 15964282|CGD_REF: CAL0114274 homozygous diploid, systematic mutation set (split-marker transposon insertion strategy to disrupt both alleles) null BWP17 viable C. albicans orf19.723 ORF BCR1 CAL0001773 PMID: 15964282|CGD_REF: CAL0114274 heterozygous diploid, classical genetics null BWP17 viable heterozygous null mutant reconstituted by transformation of the homozygous null with the wild-type gene C. albicans orf19.723 ORF BCR1 CAL0001773 PMID: 19463063|CGD_REF: CAL0123630 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.723 ORF BCR1 CAL0001773 PMID: 19779551|CGD_REF: CAL0124331 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.723 ORF BCR1 CAL0001773 PMID: 20041210|CGD_REF: CAL0124764 homozygous diploid, systematic mutation set null SN152 resistance to chemicals: decreased rapamycin strongly sensitive C. albicans orf19.723 ORF BCR1 CAL0001773 PMID: 15964282|CGD_REF: CAL0114274 homozygous diploid, systematic mutation set (split-marker transposon insertion strategy to disrupt both alleles) null BWP17 biofilm formation: decreased produces a rudimentary biofilm less than 20 um deep on a silicone substrate in vitro C. albicans orf19.723 ORF BCR1 CAL0001773 PMID: 15964282|CGD_REF: CAL0114274 heterozygous diploid, classical genetics null BWP17 biofilm formation: normal heterozygous null mutant reconstituted by transformation of the homozygous null with the wild-type gene C. albicans orf19.723 ORF BCR1 CAL0001773 PMID: 15964282|CGD_REF: CAL0114274 homozygous diploid, classical genetics null BWP17 hyphal growth: normal under various conditions, including mixed biofilms composed of wild-type and mutant cells C. albicans orf19.723 ORF BCR1 CAL0001773 PMID: 20041210|CGD_REF: CAL0124764 homozygous diploid, systematic mutation set null SN152 invasive growth: increased SD or YEPD media at 30 or 37 deg C strongly increased C. albicans orf19.723 ORF BCR1 CAL0001773 PMID: 19779551|CGD_REF: CAL0124331 homozygous diploid, classical genetics null Not recorded colony appearance: abnormal solid Spider medium C. albicans orf19.723 ORF BCR1 CAL0001773 PMID: 20041210|CGD_REF: CAL0124764 homozygous diploid, systematic mutation set null SN152 colony appearance: abnormal Spider medium slightly reduced colony wrinkling and enhanced peripheral filamentation C. albicans orf19.723 ORF BCR1 CAL0001773 PMID: 20041210|CGD_REF: CAL0124764 homozygous diploid, systematic mutation set null SN152 colony color: abnormal CHROMagar medium at 30 deg C darker than normal C. albicans orf19.723 ORF BCR1 CAL0001773 PMID: 20041210|CGD_REF: CAL0124764 homozygous diploid, systematic mutation set null SN152 resistance to chemicals: decreased caffeine strongly sensitive C. albicans orf19.723 ORF BCR1 CAL0001773 PMID: 21283544|CGD_REF: CAL0141430 homozygous diploid, classical genetics null Other C. albicans biofilm formation: decreased mouse oropharyngeal infection C. albicans orf19.723 ORF BCR1 CAL0001773 PMID: 21407800|CGD_REF: CAL0141800 homozygous diploid, classical genetics null BWP17 interaction with host/environment: abnormal significantly reduced adhesion and damage to epithelial cells, but normal invasion ex vivo model of infection C. albicans orf19.723 ORF BCR1 CAL0001773 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: decreased growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.723 ORF BCR1 CAL0001773 PMID: 19463063|CGD_REF: CAL0123630 homozygous diploid, classical genetics (split-marker transposon insertion strategy to disrupt both alleles) null BWP17 virulence: normal insect infection (Toll mutant D. melanogaster invasive infection) C. albicans orf19.723 ORF BCR1 CAL0001773 PMID: 20415594|CGD_REF: CAL0125421 homozygous diploid, classical genetics null SC5314 resistance to killing by host cells: decreased mutants are hypersusceptible to phagocyte-mediated killing C. albicans orf19.723 ORF BCR1 CAL0001773 PMID: 22265407|CGD_REF: CAL0000143925 homozygous diploid, classical genetics null Other C. albicans biofilm formation: decreased C. albicans orf19.723 ORF BCR1 CAL0001773 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: abnormal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.723 ORF BCR1 CAL0001773 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, classical genetics null SN152 germ tube formation: decreased serum-containing medium C. albicans orf19.723 ORF BCR1 CAL0001773 PMID: 22589718|CGD_REF: CAL0000157315 heterozygous diploid, classical genetics reduction of function bcr1AA (phosphodefective mutations T191A, S556A,) BWP17 biofilm formation: decreased C. albicans orf19.723 ORF BCR1 CAL0001773 PMID: 22589718|CGD_REF: CAL0000157315 heterozygous diploid, classical genetics gain of function bcr1EE (phosphomimetic mutations T191E, S556E) BWP17 biofilm formation: increased C. albicans orf19.723 ORF BCR1 CAL0001773 PMID: 22589718|CGD_REF: CAL0000157315 heterozygous diploid, large-scale survey reduction of function bcr1AA (phosphodefective mutations T191A, S556A,) BWP17 virulence: decreased mouse intravenous infection C. albicans orf19.723 ORF BCR1 CAL0001773 PMID: 22589718|CGD_REF: CAL0000157315 heterozygous diploid, classical genetics gain of function bcr1EE (phosphomimetic mutations T191E, S556E) BWP17 virulence: decreased mouse intravenous infection C. albicans orf19.723 ORF BCR1 CAL0001773 PMID: 22359502|CGD_REF: CAL0000144048 homozygous diploid, classical genetics null BWP17 adhesion: decreased insertion mutant, independent BWP17 and SN152 deletion mutants also tested C. albicans orf19.723 ORF BCR1 CAL0001773 PMID: 22359502|CGD_REF: CAL0000144048 homozygous diploid, classical genetics null BWP17 viable insertion mutant, independent BWP17 and SN152 deletion mutants also tested C. albicans orf19.723 ORF BCR1 CAL0001773 PMID: 22544909|CGD_REF: CAL0000157240 homozygous diploid, classical genetics null BWP17 virulence: decreased mutant has decreased oral fungal burden at day 1 and 5 post-infection other model (Immunosuppressed mice) C. albicans orf19.723 ORF BCR1 CAL0001773 PMID: 16839200|CGD_REF: CAL0116292 homozygous diploid, classical genetics null BWP17 biofilm formation: abnormal C. albicans orf19.723 ORF BCR1 CAL0001773 PMID: 23572557|CGD_REF: CAL0000158900 homozygous diploid, classical genetics null BWP17 resistance to chemicals: decreased fluconazole RPMI+MOPS+Histidine medium , 6 hours without shaking at 37 degrees C 24 hr fluconazole treatment in 96 well plates C. albicans orf19.723 ORF BCR1 CAL0001773 PMID: 23637598|CGD_REF: CAL0000172002 homozygous diploid, classical genetics null arg1::hisG/arg1::hisG bcr1::HIS1/bcr1::LEU2 SC5314 biofilm formation: decreased 37 degrees C in Spider medium 24 h or 60 h with gentle shaking C. albicans orf19.723 ORF BCR1 CAL0001773 PMID: 23637598|CGD_REF: CAL0000172002 homozygous diploid, classical genetics null a/a arg1::hisG/arg1::hisG bcr1::HIS1/bcr1::LEU2 P37005 biofilm formation: decreased 37 degrees C in Spider medium deficient in 10uM alpha pheromone stimulated biofilms C. albicans orf19.723 ORF BCR1 CAL0001773 PMID: 23563485|CGD_REF: CAL0000158903 homozygous diploid, classical genetics null a/alpha bcr1::ARG4/bcr1::URA3 BWP17 biofilm formation: abnormal RPMI medium. Biofilm disks were incubated at 29 degrees C with rocking for 16 hr or 48 hr defective in vertical orientation of hyphae, extracellular matrix production, Sypro Ruby impermeability, human PMN invasion and fluconzole resistance (41% of wild-type); decreased biofilm thickness C. albicans orf19.723 ORF BCR1 CAL0001773 PMID: 23563485|CGD_REF: CAL0000158903 homozygous diploid, classical genetics repressible (a/a)-TETp-BCR1 (minus doxycyclin) BWP17 biofilm formation: abnormal RPMI medium. Biofilm disks were incubated at 29 degrees C with rocking for48 hr a/a biofilms treated with doxycycline were reproducibly thinner than parental biofilms, showed increased Sypro Ruby penetration and permeability to human PMNs but were indistinguishable architecturally; doxycyclin addition partially restore these phenotypes C. albicans orf19.723 ORF BCR1 CAL0001773 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.723 ORF BCR1 CAL0001773 PMID: 23808664|CGD_REF: CAL0000172530 homozygous diploid, systematic mutation set null CAI-4 filamentous growth: increased Lee's glucose medium at 25 deg opaque cells C. albicans orf19.723 ORF BCR1 CAL0001773 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.7231 ORF FTR2 CAL0003834 PMID: 10807578|CGD_REF: CAL0081311 homozygous diploid, classical genetics null SC5314 utilization of iron source: normal wild-type high-affinity iron uptake and growth under iron-depletion conditions C. albicans orf19.7231 ORF FTR2 CAL0003834 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.7231 ORF FTR2 CAL0003834 PMID: 10807578|CGD_REF: CAL0081311 homozygous diploid, classical genetics null SC5314 viable C. albicans orf19.7231 ORF FTR2 CAL0003834 PMID: 16954314|CGD_REF: CAL0116835 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased fluconazole reversible by iron supplementation C. albicans orf19.7231 ORF FTR2 CAL0003834 PMID: 10807578|CGD_REF: CAL0081311 homozygous diploid, classical genetics null SC5314 virulence: normal wild-type kidney colonization mouse intravenous infection C. albicans orf19.7232 ORF IRR1 CAL0003835 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.7234 ORF CAL0003837 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.7235 ORF CAL0003838 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.7235 ORF CAL0003838 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, competitive growth (haploinsufficient phenotype assay, barcode deletion set) null SC5314 resistance to chemicals: decreased amphotericin B C. albicans orf19.7236 ORF TIF35 CAL0003839 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, competitive growth (haploinsufficient phenotype assay, barcode deletion set) null SC5314 vegetative growth: decreased rate C. albicans orf19.7236 ORF TIF35 CAL0003839 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.7236 ORF TIF35 CAL0003839 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient YPD medium C. albicans orf19.7236 ORF TIF35 CAL0003839 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient SC medium C. albicans orf19.7236 ORF TIF35 CAL0003839 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient YNB medium C. albicans orf19.7236 ORF TIF35 CAL0003839 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient SLAD medium C. albicans orf19.7236 ORF TIF35 CAL0003839 PMID: 21135205|CGD_REF: CAL0139967 heterozygous diploid, large-scale survey (large-scale identification of genes essential for virulence in mouse) repressible CAI-4 virulence: absent mouse intravenous infection C. albicans orf19.7238 ORF NPL3 CAL0003843 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.7238 ORF NPL3 CAL0003843 PMID: 21414038|CGD_REF: CAL0141808 homozygous diploid, classical genetics null BWP17 viable C. albicans orf19.7238 ORF NPL3 CAL0003843 PMID: 23381995|CGD_REF: CAL0000158490 homozygous diploid, classical genetics null BWP17 viable C. albicans orf19.7238 ORF NPL3 CAL0003843 PMID: 23381995|CGD_REF: CAL0000158490 homozygous diploid, classical genetics null BWP17 cold sensitivity: increased 16 deg C. albicans orf19.7243 ORF CAL0003875 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.7245 ORF CAL0003878 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.7247 ORF RIM101 CAL0003879 PMID: 12524333|CGD_REF: CAL0080691 homozygous diploid, systematic mutation set (homozygous insertion mutants generated with URA3-ARG4-URA3 (UAU1) cassette) null BWP17 metal resistance: decreased lithium chloride slight growth defect in presence of LiCl C. albicans orf19.7247 ORF RIM101 CAL0003879 PMID: 20041210|CGD_REF: CAL0124764 homozygous diploid, systematic mutation set null SN152 ionic stress resistance: decreased lithium chloride severely sensitive C. albicans orf19.7247 ORF RIM101 CAL0003879 PMID: 15590834|CGD_REF: CAL0082485 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased lithium(1+) C. albicans orf19.7247 ORF RIM101 CAL0003879 PMID: 10074081|CGD_REF: CAL0080678 homozygous diploid, classical genetics null Not recorded filamentous growth: absent solid Spider medium C. albicans orf19.7247 ORF RIM101 CAL0003879 PMID: 15590834|CGD_REF: CAL0082485 homozygous diploid, classical genetics null BWP17 filamentous growth: absent solid M199 medium, pH 8 C. albicans orf19.7247 ORF RIM101 CAL0003879 PMID: 15590834|CGD_REF: CAL0082485 homozygous diploid, classical genetics null BWP17 filamentous growth: decreased C. albicans orf19.7247 ORF RIM101 CAL0003879 PMID: 15590834|CGD_REF: CAL0082485 homozygous diploid, classical genetics null BWP17 germ tube formation: decreased liquid serum-containing medium C. albicans orf19.7247 ORF RIM101 CAL0003879 PMID: 19188358|CGD_REF: CAL0122313 homozygous diploid, classical genetics null Not recorded germ tube formation: normal arginine- or urea-containing media or 5% carbon dioxide C. albicans orf19.7247 ORF RIM101 CAL0003879 PMID: 17005841|CGD_REF: CAL0116696 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased micafungin C. albicans orf19.7247 ORF RIM101 CAL0003879 PMID: 17005841|CGD_REF: CAL0116696 homozygous diploid, classical genetics null Not recorded resistance to chemicals: normal nikkomycin Z C. albicans orf19.7247 ORF RIM101 CAL0003879 PMID: 17005841|CGD_REF: CAL0116696 homozygous diploid, classical genetics null Not recorded resistance to chemicals: normal nikkomycin Z C. albicans orf19.7247 ORF RIM101 CAL0003879 PMID: 17005841|CGD_REF: CAL0116696 heterozygous diploid, classical genetics activation Not recorded resistance to chemicals: increased nikkomycin Z C. albicans orf19.7247 ORF RIM101 CAL0003879 PMID: 17005841|CGD_REF: CAL0116696 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased caspofungin C. albicans orf19.7247 ORF RIM101 CAL0003879 PMID: 18503007|CGD_REF: CAL0119016 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased iron chelators pH 6 severe growth defect in the presence of iron chelator bathophenanthroline disulphonate C. albicans orf19.7247 ORF RIM101 CAL0003879 PMID: 15554973|CGD_REF: CAL0082478 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased iron chelators C. albicans orf19.7247 ORF RIM101 CAL0003879 PMID: 20041210|CGD_REF: CAL0124764 homozygous diploid, systematic mutation set null SN152 resistance to chemicals: decreased EDTA (0.75 mM ethylenediaminetetraacetic acid) strongly sensitive C. albicans orf19.7247 ORF RIM101 CAL0003879 PMID: 17005841|CGD_REF: CAL0116696 homozygous diploid, classical genetics null Not recorded resistance to chemicals: normal Calcofluor White C. albicans orf19.7247 ORF RIM101 CAL0003879 PMID: 17005841|CGD_REF: CAL0116696 homozygous diploid, classical genetics null Not recorded resistance to chemicals: normal Calcofluor White C. albicans orf19.7247 ORF RIM101 CAL0003879 PMID: 12819929|CGD_REF: CAL0081778 homozygous diploid, classical genetics null Not recorded vegetative growth: decreased rate alkaline pH C. albicans orf19.7247 ORF RIM101 CAL0003879 PMID: 18503007|CGD_REF: CAL0119016 homozygous diploid, classical genetics null Not recorded vegetative growth: normal rate solid YPG medium C. albicans orf19.7247 ORF RIM101 CAL0003879 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.7247 ORF RIM101 CAL0003879 PMID: 12524333|CGD_REF: CAL0080691 homozygous diploid, systematic mutation set (homozygous insertion mutants generated with URA3-ARG4-URA3 (UAU1) cassette) null BWP17 viable C. albicans orf19.7247 ORF RIM101 CAL0003879 PMID: 14663094|CGD_REF: CAL0080633 homozygous diploid, systematic mutation set (homozygous insertion mutants generated with URA3-ARG4-URA3 (UAU1) cassette) null BWP17 viable C. albicans orf19.7247 ORF RIM101 CAL0003879 PMID: 15964282|CGD_REF: CAL0114274 homozygous diploid, systematic mutation set (split-marker transposon insertion strategy to disrupt both alleles) null BWP17 viable C. albicans orf19.7247 ORF RIM101 CAL0003879 PMID: 10074081|CGD_REF: CAL0080678 heterozygous diploid, classical genetics null Not recorded viable C. albicans orf19.7247 ORF RIM101 CAL0003879 PMID: 10074081|CGD_REF: CAL0080678 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.7247 ORF RIM101 CAL0003879 PMID: 19463063|CGD_REF: CAL0123630 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.7247 ORF RIM101 CAL0003879 PMID: 17005841|CGD_REF: CAL0116696 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased sodium dodecyl sulfate C. albicans orf19.7247 ORF RIM101 CAL0003879 PMID: 17005841|CGD_REF: CAL0116696 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased sodium dodecyl sulfate C. albicans orf19.7247 ORF RIM101 CAL0003879 PMID: 20041210|CGD_REF: CAL0124764 homozygous diploid, systematic mutation set null SN152 resistance to chemicals: decreased sodium dodecyl sulfate strongly sensitive C. albicans orf19.7247 ORF RIM101 CAL0003879 PMID: 20041210|CGD_REF: CAL0124764 homozygous diploid, systematic mutation set null SN152 resistance to chemicals: decreased rapamycin strongly sensitive C. albicans orf19.7247 ORF RIM101 CAL0003879 PMID: 12524333|CGD_REF: CAL0080691 homozygous diploid, systematic mutation set (homozygous insertion mutants generated with URA3-ARG4-URA3 (UAU1) cassette) null BWP17 alkaline pH resistance: decreased slight growth defect at pH 9 C. albicans orf19.7247 ORF RIM101 CAL0003879 PMID: 15590834|CGD_REF: CAL0082485 homozygous diploid, classical genetics null Not recorded alkaline pH resistance: decreased pH 9 C. albicans orf19.7247 ORF RIM101 CAL0003879 PMID: 20041210|CGD_REF: CAL0124764 homozygous diploid, systematic mutation set null SN152 alkaline pH resistance: decreased pH 10.5 strongly sensitive C. albicans orf19.7247 ORF RIM101 CAL0003879 PMID: 10629054|CGD_REF: CAL0081720 homozygous diploid, classical genetics null rim101::ARG4/rim101::URA3 BWP17 hyphal growth: absent alkaline pH C. albicans orf19.7247 ORF RIM101 CAL0003879 PMID: 10629054|CGD_REF: CAL0081720 heterozygous diploid, classical genetics null rim101::ARG4/rim101::URA3 BWP17 viable C. albicans orf19.7247 ORF RIM101 CAL0003879 PMID: 10629054|CGD_REF: CAL0081720 homozygous diploid, classical genetics null rim101::ARG4/rim101::URA3 BWP17 viable C. albicans orf19.7247 ORF RIM101 CAL0003879 PMID: 10620776|CGD_REF: CAL0081775 homozygous diploid, classical genetics null rim101::dpl200 CAI-4 filamentous growth: absent C. albicans orf19.7247 ORF RIM101 CAL0003879 PMID: 10620776|CGD_REF: CAL0081775 heterozygous diploid, classical genetics null rim101::dpl200 CAI-4 viable C. albicans orf19.7247 ORF RIM101 CAL0003879 PMID: 10620776|CGD_REF: CAL0081775 homozygous diploid, classical genetics null rim101::dpl200 CAI-4 viable C. albicans orf19.7247 ORF RIM101 CAL0003879 PMID: 10601210|CGD_REF: CAL0081755 heterozygous diploid, classical genetics null rim101::hisG/rim101::hisG-URA3-hisG CAI-4 filamentous growth: decreased various media C. albicans orf19.7247 ORF RIM101 CAL0003879 PMID: 10601210|CGD_REF: CAL0081755 homozygous diploid, classical genetics null rim101::hisG/rim101::hisG-URA3-hisG CAI-4 filamentous growth: decreased various media C. albicans orf19.7247 ORF RIM101 CAL0003879 PMID: 10601210|CGD_REF: CAL0081755 heterozygous diploid, classical genetics null rim101::hisG/rim101::hisG-URA3-hisG CAI-4 viable C. albicans orf19.7247 ORF RIM101 CAL0003879 PMID: 10601210|CGD_REF: CAL0081755 homozygous diploid, classical genetics null rim101::hisG/rim101::hisG-URA3-hisG CAI-4 viable C. albicans orf19.7247 ORF RIM101 CAL0003879 PMID: 15964282|CGD_REF: CAL0114274 homozygous diploid, systematic mutation set (split-marker transposon insertion strategy to disrupt both alleles) null BWP17 biofilm formation: normal C. albicans orf19.7247 ORF RIM101 CAL0003879 PMID: 14663094|CGD_REF: CAL0080633 homozygous diploid, systematic mutation set (homozygous insertion mutants generated with URA3-ARG4-URA3 (UAU1) cassette) null BWP17 hyphal growth: decreased embedded in solid medium C. albicans orf19.7247 ORF RIM101 CAL0003879 PMID: 17005841|CGD_REF: CAL0116696 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased voriconazole C. albicans orf19.7247 ORF RIM101 CAL0003879 PMID: 14663094|CGD_REF: CAL0080633 homozygous diploid, systematic mutation set (homozygous insertion mutants generated with URA3-ARG4-URA3 (UAU1) cassette) null BWP17 chlamydospore formation: decreased C. albicans orf19.7247 ORF RIM101 CAL0003879 PMID: 20041210|CGD_REF: CAL0124764 homozygous diploid, systematic mutation set null SN152 colony appearance: abnormal Spider medium colonies are wrinkled but are flatter than wild-type colonies C. albicans orf19.7247 ORF RIM101 CAL0003879 PMID: 20041210|CGD_REF: CAL0124764 homozygous diploid, systematic mutation set null SN152 metal resistance: decreased copper(2+) severely sensitive C. albicans orf19.7247 ORF RIM101 CAL0003879 PMID: 17005841|CGD_REF: CAL0116696 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased fluconazole C. albicans orf19.7247 ORF RIM101 CAL0003879 PMID: 16040970|CGD_REF: CAL0114427 homozygous diploid, classical genetics null BWP17 induction of host response: decreased endothelial cell monolayers decreased induction of proinflammatory cytokine response C. albicans orf19.7247 ORF RIM101 CAL0003879 PMID: 16040970|CGD_REF: CAL0114427 homozygous diploid, classical genetics null BWP17 induction of host response: decreased decreased induction of proinflammatory cytokine response ex vivo model of infection (reconstituted human oral mucosa) C. albicans orf19.7247 ORF RIM101 CAL0003879 PMID: 16040970|CGD_REF: CAL0114427 homozygous diploid, classical genetics null BWP17 induction of host response: decreased decreased induction of proinflammatory cytokine response in vitro model of infection (oral keratinocyte and dermal microvascular endothelial cell monolayers) C. albicans orf19.7247 ORF RIM101 CAL0003879 PMID: 16040970|CGD_REF: CAL0114427 homozygous diploid, classical genetics null BWP17 interaction with host/environment: decreased decreased cell monolayer invasion and induction of proinflammatory cytokine response ex vivo model of infection (reconstituted human oral mucosa) C. albicans orf19.7247 ORF RIM101 CAL0003879 PMID: 16040970|CGD_REF: CAL0114427 homozygous diploid, classical genetics null BWP17 interaction with host/environment: decreased decreased cell monolayer invasion and induction of proinflammatory cytokine response in vitro model of infection (oral keratinocyte and dermal microvascular endothelial cell monolayers) C. albicans orf19.7247 ORF RIM101 CAL0003879 PMID: 21407800|CGD_REF: CAL0141800 homozygous diploid, classical genetics null BWP17 interaction with host/environment: abnormal significantly reduces adhesion, invasion, and damage to epithelial cells ex vivo model of infection C. albicans orf19.7247 ORF RIM101 CAL0003879 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.7247 ORF RIM101 CAL0003879 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: abnormal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.7247 ORF RIM101 CAL0003879 PMID: 12524333|CGD_REF: CAL0080691 homozygous diploid, systematic mutation set (homozygous insertion mutants generated with URA3-ARG4-URA3 (UAU1) cassette) null BWP17 virulence: decreased mouse intravenous infection C. albicans orf19.7247 ORF RIM101 CAL0003879 PMID: 19463063|CGD_REF: CAL0123630 homozygous diploid, systematic mutation set (split-marker transposon insertion strategy to disrupt both alleles) null BWP17 virulence: normal Toll mutant D. melanogaster invasive infection insect infection C. albicans orf19.7247 ORF RIM101 CAL0003879 PMID: 19666778|CGD_REF: CAL0123941 homozygous diploid, classical genetics null Not recorded virulence: decreased C. elegans infection C. albicans orf19.7247 ORF RIM101 CAL0003879 PMID: 10992507|CGD_REF: CAL0081776 homozygous diploid, classical genetics null Not recorded virulence: decreased endothelial cells decreased capacity to damage cells in vitro model of infection C. albicans orf19.7247 ORF RIM101 CAL0003879 PMID: 10992507|CGD_REF: CAL0081776 homozygous diploid, classical genetics null Not recorded virulence: decreased decreased kidney colonization late in infection mouse intravenous infection C. albicans orf19.7247 ORF RIM101 CAL0003879 PMID: 10992507|CGD_REF: CAL0081776 homozygous diploid, classical genetics null Not recorded virulence: decreased mouse intravenous infection C. albicans orf19.7247 ORF RIM101 CAL0003879 PMID: 10992507|CGD_REF: CAL0081776 heterozygous diploid, classical genetics null Not recorded virulence: normal mouse intravenous infection C. albicans orf19.7247 ORF RIM101 CAL0003879 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.7247 ORF RIM101 CAL0003879 PMID: 20375342|CGD_REF: CAL0125177 homozygous diploid, classical genetics null BWP17 filamentous growth: decreased solid M199 medium pH 7.3 or 8.0 C. albicans orf19.7247 ORF RIM101 CAL0003879 PMID: 20375342|CGD_REF: CAL0125177 homozygous diploid, classical genetics null BWP17 virulence: decreased BALB/C mice mouse corneal infection C. albicans orf19.7247 ORF RIM101 CAL0003879 PMID: 20375342|CGD_REF: CAL0125177 homozygous diploid, classical genetics null BWP17 invasive growth: decreased porcine corneal tissue depth of hyphal penetration into corneal tissue is reduced ex vivo model of infection C. albicans orf19.7247 ORF RIM101 CAL0003879 PMID: 20581294|CGD_REF: CAL0125802 homozygous diploid, classical genetics null BWP17 alkaline pH resistance: decreased YPD pH 9, 2 days at 37 degrees C C. albicans orf19.7247 ORF RIM101 CAL0003879 PMID: 20581294|CGD_REF: CAL0125802 homozygous diploid, classical genetics null BWP17 filamentous growth: decreased M199 pH 8 plates, 37 degrees C, 6 days no peripheral hyphae produced C. albicans orf19.7247 ORF RIM101 CAL0003879 PMID: 20581294|CGD_REF: CAL0125802 homozygous diploid, classical genetics null BWP17 virulence: decreased nearly two logs of lower burden than wild type mouse oropharyngeal infection (cortisone-immunosuppressed mice) C. albicans orf19.7247 ORF RIM101 CAL0003879 PMID: 20581294|CGD_REF: CAL0125802 homozygous diploid, classical genetics null BWP17 metal resistance: decreased lithium chloride (150 mM) YPD plus 150 mM lithium chloride C. albicans orf19.7247 ORF RIM101 CAL0003879 PMID: 20581294|CGD_REF: CAL0125802 homozygous diploid, classical genetics null BWP17 resistance to chemicals: decreased iron chelators YPD plus 150 micromolar bathophenanthrolinedisulfonic acid (BPS) C. albicans orf19.7247 ORF RIM101 CAL0003879 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.7255 ORF RPC10 CAL0003902 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.7256 ORF CAL0003903 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.7257 ORF MLH3 CAL0003904 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.7258 ORF DDI1 CAL0003905 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.726 ORF PPZ1 CAL0001775 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.726 ORF PPZ1 CAL0001775 PMID: 18708562|CGD_REF: CAL0119375 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.726 ORF PPZ1 CAL0001775 PMID: 22750657|CGD_REF: CAL0000157583 homozygous diploid, classical genetics null SN87 resistance to chemicals: decreased diamide C. albicans orf19.726 ORF PPZ1 CAL0001775 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: decreased growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.726 ORF PPZ1 CAL0001775 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: abnormal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.726 ORF PPZ1 CAL0001775 PMID: 22343349|CGD_REF: CAL0000144047 homozygous diploid, classical genetics null SN87 germ tube formation: delayed decreased rate of germ tube formation in 90% sheep serum; catches up with wild-type after ~90 minutes C. albicans orf19.726 ORF PPZ1 CAL0001775 PMID: 22343349|CGD_REF: CAL0000144047 homozygous diploid, classical genetics null SN87 viable C. albicans orf19.726 ORF PPZ1 CAL0001775 PMID: 22343349|CGD_REF: CAL0000144047 homozygous diploid, classical genetics null SN87 resistance to chemicals: increased hygromycin B|lithium chloride|spermine C. albicans orf19.726 ORF PPZ1 CAL0001775 PMID: 22343349|CGD_REF: CAL0000144047 homozygous diploid, classical genetics null SN87 virulence: decreased mouse intravenous infection C. albicans orf19.726 ORF PPZ1 CAL0001775 PMID: 22750657|CGD_REF: CAL0000157583 homozygous diploid, classical genetics null SN87 resistance to chemicals: decreased tert-butyl hydroperoxide C. albicans orf19.726 ORF PPZ1 CAL0001775 PMID: 22343349|CGD_REF: CAL0000144047 homozygous diploid, classical genetics null SN87 resistance to chemicals: decreased Calcofluor White|Congo Red|caffeine|potassium chloride C. albicans orf19.726 ORF PPZ1 CAL0001775 PMID: 18708562|CGD_REF: CAL0119375 homozygous diploid, classical genetics null Not recorded virulence: normal silkworm insect infection C. albicans orf19.726 ORF PPZ1 CAL0001775 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.726 ORF PPZ1 CAL0001775 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.7261 ORF GDI1 CAL0003925 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.7264 ORF CAL0003932 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.7265 ORF CAL0003935 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.7269 ORF CAL0003938 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.7275 ORF FGR24 CAL0003963 PMID: 12773383|CGD_REF: CAL0087974 heterozygous diploid, classical genetics (haploinsufficient phenotype assay) null CAI-4 filamentous growth: increased solid YEPD plus serum heterozygous transposon insertion C. albicans orf19.7275 ORF FGR24 CAL0003963 PMID: 12773383|CGD_REF: CAL0087974 heterozygous diploid, classical genetics (haploinsufficient phenotype assay) null CAI-4 viable heterozygous transposon insertion C. albicans orf19.728 ORF TSC11 CAL0001779 PMID: 12773383|CGD_REF: CAL0087974 heterozygous diploid, classical genetics (haploinsufficient phenotype assay) unspecified CAI-4 filamentous growth: increased solid Spider medium or solid YEPD plus serum C. albicans orf19.728 ORF TSC11 CAL0001779 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.728 ORF TSC11 CAL0001779 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.728 ORF TSC11 CAL0001779 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: abnormal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.728 ORF TSC11 CAL0001779 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: decreased rate liquid synthetic complete medium C. albicans orf19.728 ORF TSC11 CAL0001779 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.7281 ORF PDK2 CAL0003985 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.7281 ORF PDK2 CAL0003985 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, competitive growth (haploinsufficient phenotype assay, barcode deletion set) null SC5314 resistance to chemicals: decreased amphotericin B C. albicans orf19.7281 ORF PDK2 CAL0003985 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.7281 ORF PDK2 CAL0003985 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.7281 ORF PDK2 CAL0003985 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.7281 ORF PDK2 CAL0003985 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.7282 ORF PEX13 CAL0003988 PMID: 18832312|CGD_REF: CAL0120314 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.7282 ORF PEX13 CAL0003988 PMID: 18832312|CGD_REF: CAL0120314 homozygous diploid, classical genetics null Not recorded peroxisomal transport: decreased defect in peroxisomal protein import mediated by PTS1 and PTS2 targeting sequences C. albicans orf19.7282 ORF PEX13 CAL0003988 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.7282 ORF PEX13 CAL0003988 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: abnormal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.7282 ORF PEX13 CAL0003988 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.7282 ORF PEX13 CAL0003988 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.7283 ORF CAL0003991 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.7285 ORF CAL0003996 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.7286 ORF RPN7 CAL0003998 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.7288 ORF CAL0004000 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.7288 ORF CAL0004000 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: decreased growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.7288 ORF CAL0004000 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.7288 ORF CAL0004000 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.7288 ORF CAL0004000 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.729 ORF CAL0001780 PMID: 12773383|CGD_REF: CAL0087974 heterozygous diploid, classical genetics (haploinsufficient phenotype assay) null CAI-4 filamentous growth: increased solid Spider medium or solid YEPD plus serum heterozygous deletion or transposon insertion C. albicans orf19.729 ORF CAL0001780 PMID: 12773383|CGD_REF: CAL0087974 heterozygous diploid, classical genetics (haploinsufficient phenotype assay) null CAI-4 filamentous growth: increased solid Spider medium heterozygous transposon insertion C. albicans orf19.729 ORF CAL0001780 PMID: 12773383|CGD_REF: CAL0087974 heterozygous diploid, classical genetics (haploinsufficient phenotype assay) null CAI-4 viable heterozygous deletion or transposon insertion C. albicans orf19.729 ORF CAL0001780 PMID: 12773383|CGD_REF: CAL0087974 heterozygous diploid, classical genetics (haploinsufficient phenotype assay) null CAI-4 viable heterozygous transposon insertion C. albicans orf19.7290 ORF CAL0004008 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.7291 ORF CAL0004011 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.7291 ORF CAL0004011 PMID: 14663094|CGD_REF: CAL0080633 homozygous diploid, systematic mutation set (homozygous insertion mutants generated with URA3-ARG4-URA3 (UAU1) cassette) null BWP17 viable C. albicans orf19.7292 ORF ARP2 CAL0004013 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, competitive growth (haploinsufficient phenotype assay, barcode deletion set) null SC5314 resistance to chemicals: decreased cytochalasin D C. albicans orf19.7292 ORF ARP2 CAL0004013 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.7292 ORF ARP2 CAL0004013 PMID: 20141603|CGD_REF: CAL0124951 homozygous diploid, classical genetics null SN95 hyphal growth: absent liquid YPD plus 10% serum at 37 deg C pseudohyphal growth occurs under hyphal-inducing conditions C. albicans orf19.7292 ORF ARP2 CAL0004013 PMID: 20141603|CGD_REF: CAL0124951 heterozygous diploid, classical genetics null SN95 hyphal growth: normal liquid YPD plus 10% serum at 37 deg C C. albicans orf19.7292 ORF ARP2 CAL0004013 PMID: 20141603|CGD_REF: CAL0124951 homozygous diploid, classical genetics null SN95 actin cytoskeleton morphology: abnormal actin patches are absent while actin cables and cytokinetic rings are still present C. albicans orf19.7292 ORF ARP2 CAL0004013 PMID: 20141603|CGD_REF: CAL0124951 heterozygous diploid, classical genetics null SN95 actin cytoskeleton morphology: abnormal actin patches are present, but decreased in number C. albicans orf19.7292 ORF ARP2 CAL0004013 PMID: 20141603|CGD_REF: CAL0124951 homozygous diploid, classical genetics null SN95 endocytosis: delayed endocytosis assayed by uptake of FM4-64 or Lucifer Yellow C. albicans orf19.7292 ORF ARP2 CAL0004013 PMID: 20141603|CGD_REF: CAL0124951 homozygous diploid, classical genetics null SN95 cell shape: abnormal cells are rounded and swollen C. albicans orf19.7292 ORF ARP2 CAL0004013 PMID: 20141603|CGD_REF: CAL0124951 homozygous diploid, classical genetics null SN95 resistance to chemicals: absent Calcofluor White (22 ug/ml) C. albicans orf19.7292 ORF ARP2 CAL0004013 PMID: 20141603|CGD_REF: CAL0124951 homozygous diploid, classical genetics null SN95 resistance to chemicals: absent Congo Red (200 ug/ml) C. albicans orf19.7292 ORF ARP2 CAL0004013 PMID: 20141603|CGD_REF: CAL0124951 homozygous diploid, classical genetics null SN95 resistance to chemicals: absent sodium dodecyl sulfate (0.01 %) C. albicans orf19.7292 ORF ARP2 CAL0004013 PMID: 20141603|CGD_REF: CAL0124951 homozygous diploid, classical genetics null SN95 resistance to chemicals: decreased fluconazole (1 ug/ml) C. albicans orf19.7292 ORF ARP2 CAL0004013 PMID: 20141603|CGD_REF: CAL0124951 homozygous diploid, classical genetics null SN95 resistance to chemicals: absent Hygromycin B (80 ug/ml) C. albicans orf19.7292 ORF ARP2 CAL0004013 PMID: 20141603|CGD_REF: CAL0124951 homozygous diploid, classical genetics null SN95 ionic stress resistance: absent sodium chloride (1.5 M) C. albicans orf19.7292 ORF ARP2 CAL0004013 PMID: 20141603|CGD_REF: CAL0124951 homozygous diploid, classical genetics null SN95 chitin deposition: abnormal cell wall chitin deposition is aberrant and random C. albicans orf19.7292 ORF ARP2 CAL0004013 PMID: 20141603|CGD_REF: CAL0124951 homozygous diploid, classical genetics null SN95 cytokinesis: decreased C. albicans orf19.7292 ORF ARP2 CAL0004013 PMID: 20141603|CGD_REF: CAL0124951 homozygous diploid, classical genetics null SN95 virulence: absent complement-5 (C5)-deficient mice no kidney colonization; does not elicit host induction of interleukin 6 (IL-6) or creatine kinase (CK) production immunosuppressed mouse intravenous infection C. albicans orf19.7292 ORF ARP2 CAL0004013 PMID: 20141603|CGD_REF: CAL0124951 homozygous diploid, classical genetics null SN95 viable C. albicans orf19.7292 ORF ARP2 CAL0004013 PMID: 20141603|CGD_REF: CAL0124951 homozygous diploid, systematic mutation set (homozygous insertion mutants generated with URA3-ARG4-URA3 (UAU1) cassette) null BWP17 hyphal growth: absent YPD plus 10% serum at 37 deg C C. albicans orf19.7292 ORF ARP2 CAL0004013 PMID: 20141603|CGD_REF: CAL0124951 homozygous diploid, systematic mutation set (homozygous insertion mutants generated with URA3-ARG4-URA3 (UAU1) cassette) null BWP17 colony appearance: abnormal 10% serum or Spider media at 37 deg C colonies are smooth C. albicans orf19.7292 ORF ARP2 CAL0004013 PMID: 20141603|CGD_REF: CAL0124951 homozygous diploid, classical genetics null SN95 induction of host response: decreased does not elicit host induction of interleukin 6 (IL-6) or creatine kinase (CK) production immunosuppressed mouse intravenous infection C. albicans orf19.7292 ORF ARP2 CAL0004013 PMID: 20141603|CGD_REF: CAL0124951 homozygous diploid, systematic mutation set (homozygous insertion mutants generated with URA3-ARG4-URA3 (UAU1) cassette) null BWP17 viable C. albicans orf19.7293 ORF MPS1 CAL0004016 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.7293 ORF MPS1 CAL0004016 PMID: 14507372|CGD_REF: CAL0088818 heterozygous diploid, large-scale survey (large-scale identification of essential genes by gene replacement and conditional expression (GRACE) method) repressible CAI-4 inviable one allele is deleted and the other is placed under repressible Tet promoter C. albicans orf19.7293 ORF MPS1 CAL0004016 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 invasive growth: decreased solid SLAD media C. albicans orf19.7296 ORF CAL0004024 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.7298 ORF CHS2 CAL0004026 PMID: 8016141|CGD_REF: CAL0081016 homozygous diploid, classical genetics null Not recorded germ tube formation: normal serum-containing medium wild-type germ tube morphology C. albicans orf19.7298 ORF CHS2 CAL0004026 PMID: 8016141|CGD_REF: CAL0081016 homozygous diploid, classical genetics null Not recorded germ tube formation: delayed C. albicans orf19.7298 ORF CHS2 CAL0004026 PMID: 14516767|CGD_REF: CAL0081014 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased Calcofluor White effect is slight C. albicans orf19.7298 ORF CHS2 CAL0004026 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.7298 ORF CHS2 CAL0004026 PMID: 8016141|CGD_REF: CAL0081016 homozygous diploid, classical genetics null Not recorded viable wild-type growth rate C. albicans orf19.7298 ORF CHS2 CAL0004026 PMID: 14516767|CGD_REF: CAL0081014 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.7298 ORF CHS2 CAL0004026 PMID: 8636047|CGD_REF: CAL0081006 heterozygous diploid, classical genetics null Not recorded viable C. albicans orf19.7298 ORF CHS2 CAL0004026 PMID: 8636047|CGD_REF: CAL0081006 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.7298 ORF CHS2 CAL0004026 PMID: 8636047|CGD_REF: CAL0081006 homozygous diploid, classical genetics null Not recorded cell wall morphology: normal chitin content is normal C. albicans orf19.7298 ORF CHS2 CAL0004026 PMID: 9493376|CGD_REF: CAL0081007 homozygous diploid, classical genetics null Not recorded cell wall morphology: abnormal C. albicans orf19.7298 ORF CHS2 CAL0004026 PMID: 8016141|CGD_REF: CAL0081016 homozygous diploid, classical genetics null Not recorded chitin deposition: decreased in germ tubes C. albicans orf19.7298 ORF CHS2 CAL0004026 PMID: 8016141|CGD_REF: CAL0081016 homozygous diploid, classical genetics null Not recorded chitin deposition: normal in yeast-form cells C. albicans orf19.7298 ORF CHS2 CAL0004026 PMID: 14516767|CGD_REF: CAL0081014 homozygous diploid, classical genetics null Not recorded chemical compound accumulation: decreased mannan decreased cell wall mannan C. albicans orf19.7298 ORF CHS2 CAL0004026 PMID: 14516767|CGD_REF: CAL0081014 homozygous diploid, classical genetics null Not recorded chemical compound accumulation: increased glucan increased cell wall glucan C. albicans orf19.7298 ORF CHS2 CAL0004026 PMID: 8636047|CGD_REF: CAL0081006 homozygous diploid, classical genetics null Not recorded virulence: normal mouse intravenous infection C. albicans orf19.7298 ORF CHS2 CAL0004026 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 invasive growth: decreased solid SLAD media C. albicans orf19.7304 ORF CAL0004507 PMID: 20023067|CGD_REF: CAL0124775 homozygous diploid, classical genetics null SC5314 viable C. albicans orf19.7304 ORF CAL0004507 PMID: 20023067|CGD_REF: CAL0124775 heterozygous diploid, classical genetics null SC5314 viable C. albicans orf19.7304 ORF CAL0004507 PMID: 20023067|CGD_REF: CAL0124775 homozygous diploid, classical genetics null SC5314 filamentous growth: normal 10% fetal calf serum C. albicans orf19.7304 ORF CAL0004507 PMID: 20023067|CGD_REF: CAL0124775 homozygous diploid, classical genetics null SC5314 invasive growth: normal growth into agar substrate C. albicans orf19.7304 ORF CAL0004507 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.7304 ORF CAL0004507 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.7304 ORF CAL0004507 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.7304 ORF CAL0004507 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient SLAD medium C. albicans orf19.7304 ORF CAL0004507 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.7305 ORF CAL0004508 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.7305 ORF CAL0004508 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.7305 ORF CAL0004508 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.7305 ORF CAL0004508 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.7306 ORF CAL0004509 PMID: 15114480|CGD_REF: CAL0080964 homozygous diploid, classical genetics null Not recorded resistance to chemicals: normal brefeldin A C. albicans orf19.7306 ORF CAL0004509 PMID: 15114480|CGD_REF: CAL0080964 heterozygous diploid, classical genetics overexpression Not recorded resistance to chemicals: normal brefeldin A C. albicans orf19.7306 ORF CAL0004509 PMID: 15114480|CGD_REF: CAL0080964 heterozygous diploid, classical genetics overexpression Not recorded oxidative stress resistance: normal 1,1'-azobis(N,N-dimethylformamide) C. albicans orf19.7306 ORF CAL0004509 PMID: 15114480|CGD_REF: CAL0080964 homozygous diploid, classical genetics null Not recorded resistance to chemicals: normal cerulenin C. albicans orf19.7306 ORF CAL0004509 PMID: 15114480|CGD_REF: CAL0080964 heterozygous diploid, classical genetics overexpression Not recorded resistance to chemicals: normal cerulenin C. albicans orf19.7306 ORF CAL0004509 PMID: 15114480|CGD_REF: CAL0080964 homozygous diploid, classical genetics null Not recorded resistance to chemicals: normal diamide C. albicans orf19.7306 ORF CAL0004509 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.7306 ORF CAL0004509 PMID: 15114480|CGD_REF: CAL0080964 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.7306 ORF CAL0004509 PMID: 15114480|CGD_REF: CAL0080964 heterozygous diploid, classical genetics overexpression Not recorded viable C. albicans orf19.7306 ORF CAL0004509 PMID: 15114480|CGD_REF: CAL0080964 homozygous diploid, classical genetics null Not recorded oxidative stress resistance: normal hydrogen peroxide C. albicans orf19.7306 ORF CAL0004509 PMID: 15114480|CGD_REF: CAL0080964 heterozygous diploid, classical genetics overexpression Not recorded oxidative stress resistance: normal hydrogen peroxide C. albicans orf19.7306 ORF CAL0004509 PMID: 15114480|CGD_REF: CAL0080964 homozygous diploid, classical genetics null Not recorded resistance to chemicals: normal 4-nitroquinoline N-oxide C. albicans orf19.7306 ORF CAL0004509 PMID: 15114480|CGD_REF: CAL0080964 heterozygous diploid, classical genetics overexpression Not recorded resistance to chemicals: normal 4-nitroquinoline N-oxide C. albicans orf19.7306 ORF CAL0004509 PMID: 15114480|CGD_REF: CAL0080964 homozygous diploid, classical genetics null Not recorded oxidative stress resistance: normal menadione C. albicans orf19.7306 ORF CAL0004509 PMID: 15114480|CGD_REF: CAL0080964 heterozygous diploid, classical genetics overexpression Not recorded oxidative stress resistance: normal menadione C. albicans orf19.7306 ORF CAL0004509 PMID: 15114480|CGD_REF: CAL0080964 homozygous diploid, classical genetics null Not recorded resistance to chemicals: normal fluconazole C. albicans orf19.7306 ORF CAL0004509 PMID: 15114480|CGD_REF: CAL0080964 heterozygous diploid, classical genetics overexpression Not recorded resistance to chemicals: normal fluconazole C. albicans orf19.7307 ORF CAL0004510 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.7308 ORF TUB1 CAL0004511 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, competitive growth (haploinsufficient phenotype assay, barcode deletion set) null SC5314 resistance to chemicals: decreased mebendazole C. albicans orf19.7308 ORF TUB1 CAL0004511 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, competitive growth (haploinsufficient phenotype assay, barcode deletion set) null SC5314 vegetative growth: decreased rate modest effect C. albicans orf19.7308 ORF TUB1 CAL0004511 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.7308 ORF TUB1 CAL0004511 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, competitive growth repressible SC5314 cell cycle progression through the G2/M phase transition: arrested cells display a large-budded terminal phenotype C. albicans orf19.7308 ORF TUB1 CAL0004511 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, competitive growth (haploinsufficient phenotype assay, barcode deletion set) null SC5314 resistance to chemicals: decreased benomyl C. albicans orf19.7308 ORF TUB1 CAL0004511 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, competitive growth (haploinsufficient phenotype assay, barcode deletion set) null SC5314 resistance to chemicals: decreased nocodazole C. albicans orf19.7308 ORF TUB1 CAL0004511 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, competitive growth (haploinsufficient phenotype assay, barcode deletion set) null SC5314 resistance to chemicals: decreased thiabendazole C. albicans orf19.7308 ORF TUB1 CAL0004511 PMID: 21135205|CGD_REF: CAL0139967 heterozygous diploid, large-scale survey (large-scale identification of genes essential for virulence in mouse) repressible CAI-4 virulence: absent mouse intravenous infection C. albicans orf19.731 ORF EMP46 CAL0001800 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.731 ORF EMP46 CAL0001800 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.731 ORF EMP46 CAL0001800 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.731 ORF EMP46 CAL0001800 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.7310 ORF CAL0004535 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.7310 ORF CAL0004535 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.7310 ORF CAL0004535 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.7310 ORF CAL0004535 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.7310 ORF CAL0004535 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.7312 ORF ERG13 CAL0004537 PMID: 12773383|CGD_REF: CAL0087974 heterozygous diploid, classical genetics (haploinsufficient phenotype assay) unspecified CAI-4 filamentous growth: increased solid Spider medium transposon insertion proximal to, but not within, the ORF C. albicans orf19.7312 ORF ERG13 CAL0004537 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.7312 ORF ERG13 CAL0004537 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, competitive growth (haploinsufficient phenotype assay, barcode deletion set) null SC5314 resistance to chemicals: decreased lovastatin C. albicans orf19.7312 ORF ERG13 CAL0004537 PMID: 21135205|CGD_REF: CAL0139967 heterozygous diploid, large-scale survey (large-scale identification of genes essential for virulence in mouse) repressible CAI-4 virulence: absent mouse intravenous infection C. albicans orf19.7313 ORF SSU1 CAL0004538 PMID: 12773383|CGD_REF: CAL0087974 heterozygous diploid, classical genetics (haploinsufficient phenotype assay) unspecified CAI-4 filamentous growth: increased solid Spider medium transposon insertion proximal to, but not within, the ORF C. albicans orf19.7313 ORF SSU1 CAL0004538 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.7313 ORF SSU1 CAL0004538 PMID: 18083829|CGD_REF: CAL0118813 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.7313 ORF SSU1 CAL0004538 PMID: 18083829|CGD_REF: CAL0118813 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased sulfite C. albicans orf19.7313 ORF SSU1 CAL0004538 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.7313 ORF SSU1 CAL0004538 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.7313 ORF SSU1 CAL0004538 PMID: 23417561|CGD_REF: CAL0000158590 homozygous diploid, classical genetics null SC5314 resistance to chemicals: decreased cysteine C. albicans orf19.7313 ORF SSU1 CAL0004538 PMID: 23417561|CGD_REF: CAL0000158590 homozygous diploid, classical genetics null SC5314 hyphal growth: decreased cysteine containing medium (5 mM) C. albicans orf19.7313 ORF SSU1 CAL0004538 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.7313 ORF SSU1 CAL0004538 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.7314 ORF CDG1 CAL0004539 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.7314 ORF CDG1 CAL0004539 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.7314 ORF CDG1 CAL0004539 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.7314 ORF CDG1 CAL0004539 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.7314 ORF CDG1 CAL0004539 PMID: 23417561|CGD_REF: CAL0000158590 homozygous diploid, classical genetics null SC5314 hyphal growth: decreased cysteine containing medium (5 mM) C. albicans orf19.7314 ORF CDG1 CAL0004539 PMID: 23417561|CGD_REF: CAL0000158590 homozygous diploid, classical genetics null SC5314 virulence: decreased mouse intravenous infection C. albicans orf19.7314 ORF CDG1 CAL0004539 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.7316 ORF CAL0004540 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, competitive growth (haploinsufficient phenotype assay, barcode deletion set) null SC5314 resistance to chemicals: decreased 5-fluorouracil C. albicans orf19.7316 ORF CAL0004540 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, competitive growth (haploinsufficient phenotype assay, barcode deletion set) null SC5314 resistance to chemicals: decreased tubercidin C. albicans orf19.7316 ORF CAL0004540 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, competitive growth (haploinsufficient phenotype assay, barcode deletion set) null SC5314 resistance to chemicals: decreased flucytosine C. albicans orf19.7316 ORF CAL0004540 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.7317 ORF UGA33 CAL0004541 PMID: 15964282|CGD_REF: CAL0114274 homozygous diploid, systematic mutation set (split-marker transposon insertion strategy to disrupt both alleles) null BWP17 viable C. albicans orf19.7317 ORF UGA33 CAL0004541 PMID: 15964282|CGD_REF: CAL0114274 homozygous diploid, systematic mutation set (split-marker transposon insertion strategy to disrupt both alleles) null BWP17 biofilm formation: normal C. albicans orf19.7317 ORF UGA33 CAL0004541 PMID: 22359502|CGD_REF: CAL0000144048 homozygous diploid, classical genetics null BWP17 viable insertion mutant, independent SN152 deletion mutant strain also tested C. albicans orf19.7317 ORF UGA33 CAL0004541 PMID: 22359502|CGD_REF: CAL0000144048 homozygous diploid, classical genetics null BWP17 adhesion: decreased insertion mutant, independent SN152 deletion mutant strain also tested C. albicans orf19.7319 ORF SUC1 CAL0004543 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.7319 ORF SUC1 CAL0004543 PMID: 14507372|CGD_REF: CAL0088818 heterozygous diploid, large-scale survey (large-scale identification of essential genes by gene replacement and conditional expression (GRACE) method) repressible CAI-4 viable one allele is deleted and the other is placed under repressible Tet promoter C. albicans orf19.7319 ORF SUC1 CAL0004543 PMID: 1974885|CGD_REF: CAL0081503 unknown ploidy, classical genetics unspecified Other C. albicans utilization of carbon source: absent sucrose C. albicans orf19.7319 ORF SUC1 CAL0004543 PMID: 22359502|CGD_REF: CAL0000144048 homozygous diploid, classical genetics null BWP17 viable insertion mutant, independent SN152 deletion mutant strain also tested C. albicans orf19.7319 ORF SUC1 CAL0004543 PMID: 22359502|CGD_REF: CAL0000144048 homozygous diploid, classical genetics null BWP17 viable insertion mutant, independent SN152 deletion mutant strain also tested C. albicans orf19.732 ORF CAL0001801 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.7320 ORF LIP7 CAL0004572 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.7320 ORF LIP7 CAL0004572 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.7320 ORF LIP7 CAL0004572 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.7320 ORF LIP7 CAL0004572 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.7320 ORF LIP7 CAL0004572 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.7322 ORF CAL0004574 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.7324 ORF THI13 CAL0004576 PMID: 14663094|CGD_REF: CAL0080633 homozygous diploid, systematic mutation set (homozygous insertion mutants generated with URA3-ARG4-URA3 (UAU1) cassette) null BWP17 viable C. albicans orf19.7327 ORF PHO88 CAL0004579 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.7328 ORF CAL0004580 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.7328 ORF CAL0004580 PMID: 21414038|CGD_REF: CAL0141808 homozygous diploid, classical genetics null BWP17 viable C. albicans orf19.7328 ORF CAL0004580 PMID: 21414038|CGD_REF: CAL0141808 homozygous diploid, classical genetics null BWP17 biofilm formation: normal C. albicans orf19.7328 ORF CAL0004580 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.7328 ORF CAL0004580 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.7328 ORF CAL0004580 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.7328 ORF CAL0004580 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.7329 ORF CAL0004581 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.7329 ORF CAL0004581 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.7329 ORF CAL0004581 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.7329 ORF CAL0004581 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.733 ORF CAL0001802 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.7330 ORF CAL0004601 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.7330 ORF CAL0004601 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.7330 ORF CAL0004601 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.7330 ORF CAL0004601 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.7330 ORF CAL0004601 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.7331 ORF FCY24 CAL0004602 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.7332 ORF ELF1 CAL0004603 PMID: 9720054|CGD_REF: CAL0080903 heterozygous diploid, classical genetics null Not recorded vegetative growth: decreased rate phenotype is intermediate between that of wild type and the homozygous null mutant C. albicans orf19.7332 ORF ELF1 CAL0004603 PMID: 9720054|CGD_REF: CAL0080903 homozygous diploid, classical genetics null Not recorded vegetative growth: decreased rate C. albicans orf19.7332 ORF ELF1 CAL0004603 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.7332 ORF ELF1 CAL0004603 PMID: 9720054|CGD_REF: CAL0080903 heterozygous diploid, classical genetics null Not recorded viable C. albicans orf19.7332 ORF ELF1 CAL0004603 PMID: 9720054|CGD_REF: CAL0080903 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.7332 ORF ELF1 CAL0004603 PMID: 9720054|CGD_REF: CAL0080903 heterozygous diploid, classical genetics null Not recorded cellular morphology: abnormal defect is less severe than that of homozygous null mutant C. albicans orf19.7332 ORF ELF1 CAL0004603 PMID: 9720054|CGD_REF: CAL0080903 homozygous diploid, classical genetics null Not recorded cellular morphology: abnormal C. albicans orf19.7335 ORF PRE8 CAL0004604 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.7337 ORF CAL0004606 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.7339 ORF BGL22 CAL0004607 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.734 ORF GLK1 CAL0001803 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.7341 ORF CAL0004629 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 invasive growth: decreased solid SLAD media C. albicans orf19.7342 ORF AXL1 CAL0004631 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.7342 ORF AXL1 CAL0004631 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.7342 ORF AXL1 CAL0004631 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.7342 ORF AXL1 CAL0004631 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.7343 ORF CAL0004633 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.7347 ORF CAL0004643 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.7347 ORF CAL0004643 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.7347 ORF CAL0004643 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.7347 ORF CAL0004643 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.7347 ORF CAL0004643 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.7349 ORF CHS4 CAL0004647 PMID: 10439400|CGD_REF: CAL0081025 homozygous diploid, classical genetics null Not recorded resistance to chemicals: increased Calcofluor White C. albicans orf19.7349 ORF CHS4 CAL0004647 PMID: 10439400|CGD_REF: CAL0081025 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.7349 ORF CHS4 CAL0004647 PMID: 10439400|CGD_REF: CAL0081025 homozygous diploid, classical genetics null Not recorded chitin deposition: abnormal reduced cell wall chitin content C. albicans orf19.7349 ORF CHS4 CAL0004647 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: decreased growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.7349 ORF CHS4 CAL0004647 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.7349 ORF CHS4 CAL0004647 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.7349 ORF CHS4 CAL0004647 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.7353 ORF CAL0004669 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.7353 ORF CAL0004669 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.7353 ORF CAL0004669 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.7353 ORF CAL0004669 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: decreased rate liquid synthetic complete medium C. albicans orf19.7353 ORF CAL0004669 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 invasive growth: decreased solid SLAD media C. albicans orf19.7353 ORF CAL0004669 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.7354 ORF LAC1 CAL0004672 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.7354 ORF LAC1 CAL0004672 PMID: 22211636|CGD_REF: CAL0000143845 homozygous diploid, classical genetics null lac1::dpl200/lac1::dpl200 CAI-4 hyphal growth: normal C. albicans orf19.7354 ORF LAC1 CAL0004672 PMID: 22211636|CGD_REF: CAL0000143845 homozygous diploid, classical genetics null lac1::dpl200/lac1::dpl200 CAI-4 viable C. albicans orf19.7355 ORF SSN8 CAL0004675 PMID: 16652171|CGD_REF: CAL0115929 homozygous diploid, classical genetics null BWP17 filamentous growth: increased YPD slight increase C. albicans orf19.7355 ORF SSN8 CAL0004675 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.7355 ORF SSN8 CAL0004675 PMID: 14663094|CGD_REF: CAL0080633 homozygous diploid, systematic mutation set (homozygous insertion mutants generated with URA3-ARG4-URA3 (UAU1) cassette) null BWP17 viable C. albicans orf19.7355 ORF SSN8 CAL0004675 PMID: 16652171|CGD_REF: CAL0115929 homozygous diploid, classical genetics null Not recorded cell wall morphology: abnormal beta-glucan is unmasked at regions of polarized growth C. albicans orf19.7355 ORF SSN8 CAL0004675 PMID: 16652171|CGD_REF: CAL0115929 homozygous diploid, classical genetics null BWP17 induction of host response: abnormal mutant elicits enhanced TNFalpha response in vitro model of infection (RAW264.7 or mouse bone marrow derived macrophages) C. albicans orf19.7355 ORF SSN8 CAL0004675 PMID: 23856128|CGD_REF: CAL0000172540 homozygous diploid, classical genetics null BWP17 resistance to chemicals: decreased propolis C. albicans orf19.7355 ORF SSN8 CAL0004675 PMID: 20140194|CGD_REF: CAL0124995 homozygous diploid, classical genetics null Other C. albicans oxidative stress resistance: decreased hydrogen peroxide C. albicans orf19.7357 ORF CAL0004679 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.7358 ORF SAM50 CAL0004681 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.7359 ORF CRZ1 CAL0004683 PMID: 20041210|CGD_REF: CAL0124764 homozygous diploid, systematic mutation set null SN152 resistance to chemicals: decreased fluconazole strongly sensitive C. albicans orf19.7359 ORF CRZ1 CAL0004683 PMID: 16044281|CGD_REF: CAL0114543 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased lithium(1+) C. albicans orf19.7359 ORF CRZ1 CAL0004683 PMID: 16468987|CGD_REF: CAL0115525 homozygous diploid, classical genetics null Not recorded resistance to chemicals: normal lithium(1+) C. albicans orf19.7359 ORF CRZ1 CAL0004683 PMID: 16468987|CGD_REF: CAL0115525 homozygous diploid, classical genetics null CAF2-1 filamentous growth: decreased solid Spider medium severe defect C. albicans orf19.7359 ORF CRZ1 CAL0004683 PMID: 19649312|CGD_REF: CAL0123929 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased micafungin (30 ng/ml) C. albicans orf19.7359 ORF CRZ1 CAL0004683 PMID: 20041210|CGD_REF: CAL0124764 homozygous diploid, systematic mutation set null SN152 resistance to chemicals: decreased fenpropimorph strongly sensitive C. albicans orf19.7359 ORF CRZ1 CAL0004683 PMID: 15964282|CGD_REF: CAL0114274 homozygous diploid, systematic mutation set (split-marker transposon insertion strategy to disrupt both alleles) null BWP17 viable C. albicans orf19.7359 ORF CRZ1 CAL0004683 PMID: 15557662|CGD_REF: CAL0082138 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.7359 ORF CRZ1 CAL0004683 PMID: 15813744|CGD_REF: CAL0104042 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.7359 ORF CRZ1 CAL0004683 PMID: 16044281|CGD_REF: CAL0114543 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.7359 ORF CRZ1 CAL0004683 PMID: 16468987|CGD_REF: CAL0115525 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.7359 ORF CRZ1 CAL0004683 PMID: 17927701|CGD_REF: CAL0118690 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.7359 ORF CRZ1 CAL0004683 PMID: 19463063|CGD_REF: CAL0123630 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.7359 ORF CRZ1 CAL0004683 PMID: 20041210|CGD_REF: CAL0124764 homozygous diploid, systematic mutation set null SN152 resistance to chemicals: decreased sodium dodecyl sulfate severely sensitive C. albicans orf19.7359 ORF CRZ1 CAL0004683 PMID: 17927701|CGD_REF: CAL0118690 homozygous diploid, classical genetics null Not recorded acid pH resistance: decreased pH 2 C. albicans orf19.7359 ORF CRZ1 CAL0004683 PMID: 18180354|CGD_REF: CAL0118822 homozygous diploid, classical genetics null SC5314 biofilm formation: normal C. albicans orf19.7359 ORF CRZ1 CAL0004683 PMID: 15964282|CGD_REF: CAL0114274 homozygous diploid, systematic mutation set (split-marker transposon insertion strategy to disrupt both alleles) null BWP17 biofilm formation: normal C. albicans orf19.7359 ORF CRZ1 CAL0004683 PMID: 19154328|CGD_REF: CAL0122236 homozygous diploid, classical genetics null Other C. albicans hyphal growth: abnormal semisolid substrate decreased hyphal tip oscillation C. albicans orf19.7359 ORF CRZ1 CAL0004683 PMID: 16044281|CGD_REF: CAL0114543 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased manganese(2+) C. albicans orf19.7359 ORF CRZ1 CAL0004683 PMID: 16468987|CGD_REF: CAL0115525 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased manganese(2+) C. albicans orf19.7359 ORF CRZ1 CAL0004683 PMID: 16044281|CGD_REF: CAL0114543 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased calcium(2+) C. albicans orf19.7359 ORF CRZ1 CAL0004683 PMID: 16468987|CGD_REF: CAL0115525 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased calcium(2+) C. albicans orf19.7359 ORF CRZ1 CAL0004683 PMID: 19002381|CGD_REF: CAL0121039 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased fluconazole Ca2+ induced resistance to fluconazole is abolished C. albicans orf19.7359 ORF CRZ1 CAL0004683 PMID: 15557662|CGD_REF: CAL0082138 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased fluconazole sensitivity is enhanced in the presence of FK506 C. albicans orf19.7359 ORF CRZ1 CAL0004683 PMID: 15813744|CGD_REF: CAL0104042 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased fluconazole slight decrease C. albicans orf19.7359 ORF CRZ1 CAL0004683 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: decreased growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.7359 ORF CRZ1 CAL0004683 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.7359 ORF CRZ1 CAL0004683 PMID: 23028789|CGD_REF: CAL0000157931 homozygous diploid, classical genetics null CAI-4 apoptosis: decreased C. albicans orf19.7359 ORF CRZ1 CAL0004683 PMID: 19463063|CGD_REF: CAL0123630 homozygous diploid, systematic mutation set (split-marker transposon insertion strategy to disrupt both alleles) null BWP17 virulence: normal Toll mutant D. melanogaster invasive infection insect infection C. albicans orf19.7359 ORF CRZ1 CAL0004683 PMID: 15557662|CGD_REF: CAL0082138 homozygous diploid, classical genetics null Not recorded virulence: normal mouse intravenous infection C. albicans orf19.7359 ORF CRZ1 CAL0004683 PMID: 16468987|CGD_REF: CAL0115525 homozygous diploid, classical genetics null Not recorded virulence: decreased mouse intravenous infection C. albicans orf19.7359 ORF CRZ1 CAL0004683 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.7359 ORF CRZ1 CAL0004683 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.736 ORF SRB8 CAL0001805 PMID: 23873866|CGD_REF: CAL0000172574 homozygous diploid, classical genetics null SN152 phenotypic switching: abnormal C. albicans orf19.736 ORF SRB8 CAL0001805 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient YPD medium C. albicans orf19.736 ORF SRB8 CAL0001805 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient SC medium C. albicans orf19.736 ORF SRB8 CAL0001805 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient YNB medium C. albicans orf19.736 ORF SRB8 CAL0001805 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient SLAD medium C. albicans orf19.7361 ORF CAL0004706 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.7362 ORF SKN1 CAL0004709 PMID: 9079924|CGD_REF: CAL0081372 homozygous diploid, classical genetics null Not recorded resistance to chemicals: normal Echinocandin B C. albicans orf19.7362 ORF SKN1 CAL0004709 PMID: 14507372|CGD_REF: CAL0088818 heterozygous diploid, large-scale survey (large-scale identification of essential genes by gene replacement and conditional expression (GRACE) method) repressible CAI-4 viable one allele is deleted and the other is placed under repressible Tet promoter C. albicans orf19.7362 ORF SKN1 CAL0004709 PMID: 9079924|CGD_REF: CAL0081372 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.7362 ORF SKN1 CAL0004709 PMID: 9079924|CGD_REF: CAL0081372 homozygous diploid, classical genetics null Not recorded cellular morphology: normal C. albicans orf19.7362 ORF SKN1 CAL0004709 PMID: 9079924|CGD_REF: CAL0081372 homozygous diploid, classical genetics null Not recorded chemical compound accumulation: normal beta-D-glucan C. albicans orf19.7363 ORF KRE6 CAL0004712 PMID: 9079924|CGD_REF: CAL0081372 heterozygous diploid, classical genetics null Not recorded resistance to chemicals: normal Echinocandin B C. albicans orf19.7363 ORF KRE6 CAL0004712 PMID: 9079924|CGD_REF: CAL0081372 heterozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased Calcofluor White effect is slight C. albicans orf19.7363 ORF KRE6 CAL0004712 PMID: 9079924|CGD_REF: CAL0081372 heterozygous diploid, classical genetics repressible Not recorded resistance to chemicals: decreased Calcofluor White C. albicans orf19.7363 ORF KRE6 CAL0004712 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.7363 ORF KRE6 CAL0004712 PMID: 14507372|CGD_REF: CAL0088818 heterozygous diploid, large-scale survey (large-scale identification of essential genes by gene replacement and conditional expression (GRACE) method) repressible CAI-4 viable one allele is deleted and the other is placed under repressible Tet promoter C. albicans orf19.7363 ORF KRE6 CAL0004712 PMID: 9079924|CGD_REF: CAL0081372 heterozygous diploid, classical genetics null Not recorded viable wild-type growth rate C. albicans orf19.7363 ORF KRE6 CAL0004712 PMID: 9079924|CGD_REF: CAL0081372 heterozygous diploid, classical genetics null Not recorded cellular morphology: normal C. albicans orf19.7363 ORF KRE6 CAL0004712 PMID: 9079924|CGD_REF: CAL0081372 homozygous diploid, classical genetics null Not recorded inviable homozygous null mutant strain could not be recovered, suggesting that the gene is essential under the selection conditions C. albicans orf19.7363 ORF KRE6 CAL0004712 PMID: 9079924|CGD_REF: CAL0081372 heterozygous diploid, classical genetics null Not recorded chemical compound accumulation: decreased (1->6)-beta-D-glucan decreased alkali-insoluble cell wall beta-1,6-glucan C. albicans orf19.7363 ORF KRE6 CAL0004712 PMID: 9079924|CGD_REF: CAL0081372 heterozygous diploid, classical genetics repressible Not recorded cytokinesis: decreased abnormal cell separation C. albicans orf19.7364 ORF CAL0004715 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.7367 ORF UBP1 CAL0004724 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.7368 ORF CAL0004726 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.7369 ORF TRM12 CAL0004728 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.7370 ORF CAL0004748 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.7370 ORF CAL0004748 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.7370 ORF CAL0004748 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.7370 ORF CAL0004748 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.7370 ORF CAL0004748 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.7371 ORF ZCF35 CAL0004750 PMID: 22581526|CGD_REF: CAL0000157314 homozygous diploid, systematic mutation set null BWP17 resistance to chemicals: decreased amphotericin B C. albicans orf19.7372 ORF MRR1 CAL0004753 PMID: 18577180|CGD_REF: CAL0119301 homozygous diploid, classical genetics gain of function Not recorded resistance to chemicals: increased brefeldin A C. albicans orf19.7372 ORF MRR1 CAL0004753 PMID: 18577180|CGD_REF: CAL0119301 homozygous diploid, classical genetics gain of function Not recorded resistance to chemicals: increased cerulenin increased resistance to cerulenin, brefeldin A and fluconazole, gain-of-function mutations K335N, Q350L, T360I, T381I, P683H , P683S , N803D, G878E, A880E, T896I, G997V, or L998F; resistance to cerulenin and brefeldin A, gain-of-function mutations R873T, W893R C. albicans orf19.7372 ORF MRR1 CAL0004753 PMID: 17983269|CGD_REF: CAL0118754 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.7372 ORF MRR1 CAL0004753 PMID: 18577180|CGD_REF: CAL0119301 homozygous diploid, classical genetics gain of function Not recorded resistance to chemicals: increased fluconazole C. albicans orf19.7374 ORF CTA4 CAL0004760 PMID: 18083829|CGD_REF: CAL0118813 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.7374 ORF CTA4 CAL0004760 PMID: 18451058|CGD_REF: CAL0118988 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.7374 ORF CTA4 CAL0004760 PMID: 18083829|CGD_REF: CAL0118813 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased nitrosyl C. albicans orf19.7374 ORF CTA4 CAL0004760 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.7374 ORF CTA4 CAL0004760 PMID: 22073120|CGD_REF: CAL0000143592 homozygous diploid, classical genetics null BWP17 viable C. albicans orf19.7374 ORF CTA4 CAL0004760 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.7374 ORF CTA4 CAL0004760 PMID: 22073120|CGD_REF: CAL0000143592 homozygous diploid, classical genetics null BWP17 invasive growth: decreased decreased agar invasion C. albicans orf19.7374 ORF CTA4 CAL0004760 PMID: 22073120|CGD_REF: CAL0000143592 homozygous diploid, classical genetics null BWP17 viable C. albicans orf19.7374 ORF CTA4 CAL0004760 PMID: 22073120|CGD_REF: CAL0000143592 homozygous diploid, classical genetics null BWP17 colony appearance: abnormal decreased colony wrinkling C. albicans orf19.7374 ORF CTA4 CAL0004760 PMID: 22073120|CGD_REF: CAL0000143592 homozygous diploid, classical genetics null BWP17 hyphal growth: decreased C. albicans orf19.7374 ORF CTA4 CAL0004760 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.7374 ORF CTA4 CAL0004760 PMID: 18083829|CGD_REF: CAL0118813 homozygous diploid, classical genetics null Not recorded virulence: decreased mouse intravenous infection C. albicans orf19.7374 ORF CTA4 CAL0004760 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.7375 ORF CAL0004764 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.7377 ORF ASE1 CAL0004769 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.7378 ORF CAL0004771 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.738 ORF MYO5 CAL0001808 PMID: 16896210|CGD_REF: CAL0116431 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased Calcofluor White C. albicans orf19.738 ORF MYO5 CAL0001808 PMID: 12455956|CGD_REF: CAL0080651 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.738 ORF MYO5 CAL0001808 PMID: 15470256|CGD_REF: CAL0090411 homozygous diploid, classical genetics null Not recorded protein secretion: normal secreted aspartyl protease C. albicans orf19.738 ORF MYO5 CAL0001808 PMID: 16896210|CGD_REF: CAL0116431 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased sodium dodecyl sulfate C. albicans orf19.738 ORF MYO5 CAL0001808 PMID: 12455956|CGD_REF: CAL0080651 homozygous diploid, classical genetics null Not recorded actin cytoskeleton morphology: abnormal depolarization of actin patches C. albicans orf19.738 ORF MYO5 CAL0001808 PMID: 15470256|CGD_REF: CAL0090411 homozygous diploid, classical genetics null Not recorded actin cytoskeleton morphology: abnormal depolarization of actin patches C. albicans orf19.738 ORF MYO5 CAL0001808 PMID: 12455956|CGD_REF: CAL0080651 homozygous diploid, classical genetics null Not recorded budding pattern: abnormal bud site selection is more random than in wild type C. albicans orf19.738 ORF MYO5 CAL0001808 PMID: 15470256|CGD_REF: CAL0090411 homozygous diploid, classical genetics null CAI-4 hyphal growth: abnormal deletions of various regions of the gene result in null or intermediate phenotypes C. albicans orf19.738 ORF MYO5 CAL0001808 PMID: 12455956|CGD_REF: CAL0080651 homozygous diploid, classical genetics null CAI-4 hyphal growth: absent various liquid and solid media some pseudohyphal growth is observed C. albicans orf19.738 ORF MYO5 CAL0001808 PMID: 15470256|CGD_REF: CAL0090411 homozygous diploid, classical genetics null Not recorded cell shape: abnormal cells are round and tend to aggregate; deletion of various regions of the protein results in null phenotypes C. albicans orf19.738 ORF MYO5 CAL0001808 PMID: 12455956|CGD_REF: CAL0080651 homozygous diploid, classical genetics null Not recorded cellular morphology: abnormal C. albicans orf19.738 ORF MYO5 CAL0001808 PMID: 12455956|CGD_REF: CAL0080651 homozygous diploid, classical genetics null Not recorded chitin deposition: abnormal C. albicans orf19.738 ORF MYO5 CAL0001808 PMID: 16896210|CGD_REF: CAL0116431 homozygous diploid, classical genetics null Not recorded chitin deposition: abnormal C. albicans orf19.738 ORF MYO5 CAL0001808 PMID: 18974864|CGD_REF: CAL0120463 homozygous diploid, classical genetics null Not recorded endocytosis: decreased defect in uptake of low concentrations of histatin-5 antimicrobial salivary peptide into the vacuole C. albicans orf19.738 ORF MYO5 CAL0001808 PMID: 16896210|CGD_REF: CAL0116431 homozygous diploid, classical genetics null Not recorded endocytosis: decreased defective fluid-phase endocytosis C. albicans orf19.738 ORF MYO5 CAL0001808 PMID: 15470256|CGD_REF: CAL0090411 homozygous diploid, classical genetics null Not recorded endocytosis: decreased C. albicans orf19.738 ORF MYO5 CAL0001808 PMID: 18466294|CGD_REF: CAL0119004 homozygous diploid, classical genetics null Not recorded utilization of iron source: absent hemoglobin C. albicans orf19.738 ORF MYO5 CAL0001808 PMID: 22408227|CGD_REF: CAL0000156981 homozygous diploid, classical genetics null myo5::hisG/myo5::hisG Other C. albicans viable C. albicans orf19.738 ORF MYO5 CAL0001808 PMID: 22408227|CGD_REF: CAL0000156981 heterozygous diploid, classical genetics conditional myo5::hisG/MET3(p)-MYO5 Other C. albicans phenotypic switching: absent required for maintenance of the opaque state; ectopic expression of WOR1 rescues the phenotypic switching defect C. albicans orf19.7380 ORF CAL0004791 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient SLAD medium C. albicans orf19.7381 ORF AHR1 CAL0004794 PMID: 20041210|CGD_REF: CAL0124764 homozygous diploid, systematic mutation set null SN152 resistance to chemicals: decreased flucytosine strongly sensitive C. albicans orf19.7381 ORF AHR1 CAL0004794 PMID: 14663094|CGD_REF: CAL0080633 homozygous diploid, systematic mutation set (homozygous insertion mutants generated with URA3-ARG4-URA3 (UAU1) cassette) null BWP17 viable C. albicans orf19.7381 ORF AHR1 CAL0004794 PMID: 16939537|CGD_REF: CAL0117180 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.7381 ORF AHR1 CAL0004794 PMID: 20041210|CGD_REF: CAL0124764 homozygous diploid, systematic mutation set null SN152 colony appearance: abnormal Spider medium at 30 deg C enhanced colony wrinkling C. albicans orf19.7381 ORF AHR1 CAL0004794 PMID: 21299649|CGD_REF: CAL0141592 homozygous diploid, classical genetics null ahr1::URA3/ahr1::HIS1 BWP17 adhesion: decreased C. albicans orf19.7381 ORF AHR1 CAL0004794 PMID: 21299649|CGD_REF: CAL0141592 homozygous diploid, classical genetics null ahr1::URA3/ahr1::HIS1 BWP17 biofilm formation: decreased C. albicans orf19.7381 ORF AHR1 CAL0004794 PMID: 21299649|CGD_REF: CAL0141592 homozygous diploid, classical genetics null ahr1::URA3/ahr1::HIS1 BWP17 hyphal growth: decreased C. albicans orf19.7381 ORF AHR1 CAL0004794 PMID: 21299649|CGD_REF: CAL0141592 homozygous diploid, classical genetics null ahr1::FRT/ahr1::FRT SN95 virulence: decreased mouse intravenous infection C. albicans orf19.7381 ORF AHR1 CAL0004794 PMID: 21315072|CGD_REF: CAL0141633 homozygous diploid, classical genetics null BWP17 phenotypic switching: increased increased frequency of white-to-opaque switch and stabilized opaque phase C. albicans orf19.7381 ORF AHR1 CAL0004794 PMID: 21315072|CGD_REF: CAL0141633 homozygous diploid, classical genetics overexpression BWP17 phenotypic switching: increased increased frequency of opaque-to white switch C. albicans orf19.7381 ORF AHR1 CAL0004794 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.7381 ORF AHR1 CAL0004794 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: abnormal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.7381 ORF AHR1 CAL0004794 PMID: 22073120|CGD_REF: CAL0000143592 homozygous diploid, classical genetics null BWP17 viable C. albicans orf19.7381 ORF AHR1 CAL0004794 PMID: 22073120|CGD_REF: CAL0000143592 homozygous diploid, classical genetics null BWP17 colony appearance: abnormal increased colony wrinkling C. albicans orf19.7381 ORF AHR1 CAL0004794 PMID: 22073120|CGD_REF: CAL0000143592 homozygous diploid, classical genetics null BWP17 viable C. albicans orf19.7381 ORF AHR1 CAL0004794 PMID: 22073120|CGD_REF: CAL0000143592 homozygous diploid, classical genetics null BWP17 hyphal growth: increased C. albicans orf19.7381 ORF AHR1 CAL0004794 PMID: 22581526|CGD_REF: CAL0000157314 homozygous diploid, systematic mutation set null BWP17 resistance to chemicals: decreased caspofungin C. albicans orf19.7381 ORF AHR1 CAL0004794 PMID: 22581526|CGD_REF: CAL0000157314 homozygous diploid, systematic mutation set null BWP17 resistance to chemicals: increased fluconazole C. albicans orf19.7381 ORF AHR1 CAL0004794 PMID: 22581526|CGD_REF: CAL0000157314 homozygous diploid, systematic mutation set null BWP17 resistance to chemicals: increased caspofungin C. albicans orf19.7381 ORF AHR1 CAL0004794 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.7381 ORF AHR1 CAL0004794 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.7383 ORF MNN9 CAL0004800 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.7383 ORF MNN9 CAL0004800 PMID: 10601199|CGD_REF: CAL0080746 homozygous diploid, classical genetics null mnn9::hisG-URA3-hisG/mnn9::hisG CAI-4 cell shape: abnormal C. albicans orf19.7383 ORF MNN9 CAL0004800 PMID: 10601199|CGD_REF: CAL0080746 homozygous diploid, classical genetics null mnn9::hisG-URA3-hisG/mnn9::hisG CAI-4 cell wall morphology: abnormal decreased cell wall mannan C. albicans orf19.7383 ORF MNN9 CAL0004800 PMID: 10672182|CGD_REF: CAL0080733 homozygous diploid, classical genetics null mnn9::hisG-URA3-hisG/mnn9::hisG CAI-4 cell wall morphology: abnormal C. albicans orf19.7383 ORF MNN9 CAL0004800 PMID: 10601199|CGD_REF: CAL0080746 homozygous diploid, classical genetics null mnn9::hisG-URA3-hisG/mnn9::hisG CAI-4 flocculation: increased C. albicans orf19.7383 ORF MNN9 CAL0004800 PMID: 10601199|CGD_REF: CAL0080746 homozygous diploid, classical genetics null mnn9::hisG-URA3-hisG/mnn9::hisG CAI-4 germ tube formation: decreased liquid YPD plus serum or RPMI 1640 media C. albicans orf19.7383 ORF MNN9 CAL0004800 PMID: 10601199|CGD_REF: CAL0080746 homozygous diploid, classical genetics null mnn9::hisG-URA3-hisG/mnn9::hisG CAI-4 hyphal growth: decreased C. albicans orf19.7383 ORF MNN9 CAL0004800 PMID: 10601199|CGD_REF: CAL0080746 homozygous diploid, classical genetics null mnn9::hisG-URA3-hisG/mnn9::hisG CAI-4 pseudohyphal growth: increased C. albicans orf19.7383 ORF MNN9 CAL0004800 PMID: 10601199|CGD_REF: CAL0080746 homozygous diploid, classical genetics null mnn9::hisG-URA3-hisG/mnn9::hisG CAI-4 resistance to chemicals: decreased Hygromycin B C. albicans orf19.7383 ORF MNN9 CAL0004800 PMID: 10601199|CGD_REF: CAL0080746 homozygous diploid, classical genetics null mnn9::hisG-URA3-hisG/mnn9::hisG CAI-4 resistance to chemicals: increased sodium orthovanadate C. albicans orf19.7383 ORF MNN9 CAL0004800 PMID: 10672182|CGD_REF: CAL0080733 homozygous diploid, classical genetics null mnn9::hisG-URA3-hisG/mnn9::hisG CAI-4 resistance to chemicals: decreased nikkomycin Z C. albicans orf19.7383 ORF MNN9 CAL0004800 PMID: 10601199|CGD_REF: CAL0080746 homozygous diploid, classical genetics null mnn9::hisG-URA3-hisG/mnn9::hisG CAI-4 resistance to enzymatic treatment: decreased glucanase C. albicans orf19.7383 ORF MNN9 CAL0004800 PMID: 10672182|CGD_REF: CAL0080733 homozygous diploid, classical genetics null mnn9::hisG-URA3-hisG/mnn9::hisG CAI-4 resistance to enzymatic treatment: decreased exochitinase C. albicans orf19.7383 ORF MNN9 CAL0004800 PMID: 10601199|CGD_REF: CAL0080746 homozygous diploid, classical genetics null mnn9::hisG-URA3-hisG/mnn9::hisG CAI-4 vegetative growth: decreased rate C. albicans orf19.7383 ORF MNN9 CAL0004800 PMID: 10601199|CGD_REF: CAL0080746 homozygous diploid, classical genetics null mnn9::hisG-URA3-hisG/mnn9::hisG CAI-4 viable C. albicans orf19.7383 ORF MNN9 CAL0004800 PMID: 14507372|CGD_REF: CAL0088818 heterozygous diploid, large-scale survey (large-scale identification of essential genes by gene replacement and conditional expression (GRACE) method) repressible CAI-4 inviable one allele is deleted and the other is placed under repressible Tet promoter C. albicans orf19.7383 ORF MNN9 CAL0004800 PMID: 23856128|CGD_REF: CAL0000172540 homozygous diploid, classical genetics null BWP17 resistance to chemicals: decreased propolis C. albicans orf19.7384 ORF NOG1 CAL0004804 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, competitive growth (haploinsufficient phenotype assay, barcode deletion set) null SC5314 resistance to chemicals: decreased 5-fluorouracil C. albicans orf19.7384 ORF NOG1 CAL0004804 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, competitive growth (haploinsufficient phenotype assay, barcode deletion set) null SC5314 resistance to chemicals: decreased tubercidin C. albicans orf19.7384 ORF NOG1 CAL0004804 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, competitive growth (haploinsufficient phenotype assay, barcode deletion set) null SC5314 resistance to chemicals: decreased flucytosine C. albicans orf19.7384 ORF NOG1 CAL0004804 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.7387 ORF ELP3 CAL0004812 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.7387 ORF ELP3 CAL0004812 PMID: 19555456|CGD_REF: CAL0123821 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.7388 ORF PBS2 CAL0004814 PMID: 15817773|CGD_REF: CAL0104043 homozygous diploid, classical genetics null RM1000 filamentous growth: increased serum-containing medium C. albicans orf19.7388 ORF PBS2 CAL0004814 PMID: 15817773|CGD_REF: CAL0104043 homozygous diploid, classical genetics null Not recorded resistance to chemicals: increased nikkomycin Z C. albicans orf19.7388 ORF PBS2 CAL0004814 PMID: 15817773|CGD_REF: CAL0104043 homozygous diploid, classical genetics null Not recorded resistance to enzymatic treatment: decreased zymolyase C. albicans orf19.7388 ORF PBS2 CAL0004814 PMID: 15817773|CGD_REF: CAL0104043 homozygous diploid, classical genetics null Not recorded hyperosmotic stress resistance: decreased decreased growth and defects in cell separation, Hog1p phosphorylation, and glycerol accumulation C. albicans orf19.7388 ORF PBS2 CAL0004814 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.7388 ORF PBS2 CAL0004814 PMID: 15817773|CGD_REF: CAL0104043 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.7388 ORF PBS2 CAL0004814 PMID: 15817773|CGD_REF: CAL0104043 homozygous diploid, classical genetics null RM1000 invasive growth: increased solid SLADH medium C. albicans orf19.7388 ORF PBS2 CAL0004814 PMID: 15817773|CGD_REF: CAL0104043 homozygous diploid, classical genetics null Not recorded oxidative stress resistance: decreased hydrogen peroxide C. albicans orf19.7388 ORF PBS2 CAL0004814 PMID: 15817773|CGD_REF: CAL0104043 homozygous diploid, classical genetics null Not recorded oxidative stress resistance: decreased menadione C. albicans orf19.7388 ORF PBS2 CAL0004814 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: decreased growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.7388 ORF PBS2 CAL0004814 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: abnormal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.7388 ORF PBS2 CAL0004814 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.7388 ORF PBS2 CAL0004814 PMID: 23689717|CGD_REF: CAL0000172329 homozygous diploid, classical genetics null Other C. albicans resistance to chemicals: decreased plant defensin NaD1 C. albicans orf19.7388 ORF PBS2 CAL0004814 PMID: 20140194|CGD_REF: CAL0124995 homozygous diploid, classical genetics null Other C. albicans oxidative stress resistance: decreased hydrogen peroxide C. albicans orf19.7388 ORF PBS2 CAL0004814 PMID: 20140194|CGD_REF: CAL0124995 homozygous diploid, classical genetics null Other C. albicans resistance to chemicals: decreased fluconazole C. albicans orf19.7388 ORF PBS2 CAL0004814 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.7389 ORF REV3 CAL0004816 PMID: 14663094|CGD_REF: CAL0080633 homozygous diploid, systematic mutation set (homozygous insertion mutants generated with URA3-ARG4-URA3 (UAU1) cassette) null BWP17 viable C. albicans orf19.7391 ORF OCH1 CAL0004830 PMID: 16263704|CGD_REF: CAL0115362 homozygous diploid, classical genetics null CAI-4 filamentous growth: abnormal hyphal induction by pH or temperature in Lee's or RPMI 1640 media mixed hyphae and pseudohyphae C. albicans orf19.7391 ORF OCH1 CAL0004830 PMID: 16263704|CGD_REF: CAL0115362 homozygous diploid, classical genetics null CAI-4 filamentous growth: absent Spider medium C. albicans orf19.7391 ORF OCH1 CAL0004830 PMID: 16263704|CGD_REF: CAL0115362 homozygous diploid, classical genetics null CAI-4 germ tube formation: abnormal serum-containing medium germ tubes are short C. albicans orf19.7391 ORF OCH1 CAL0004830 PMID: 16263704|CGD_REF: CAL0115362 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased Hygromycin B C. albicans orf19.7391 ORF OCH1 CAL0004830 PMID: 16263704|CGD_REF: CAL0115362 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased tunicamycin C. albicans orf19.7391 ORF OCH1 CAL0004830 PMID: 16263704|CGD_REF: CAL0115362 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased Calcofluor White C. albicans orf19.7391 ORF OCH1 CAL0004830 PMID: 16263704|CGD_REF: CAL0115362 homozygous diploid, classical genetics null Not recorded heat sensitivity: increased C. albicans orf19.7391 ORF OCH1 CAL0004830 PMID: 16263704|CGD_REF: CAL0115362 homozygous diploid, classical genetics null Not recorded vegetative growth: decreased rate rate is 75% of wild type C. albicans orf19.7391 ORF OCH1 CAL0004830 PMID: 16263704|CGD_REF: CAL0115362 heterozygous diploid, classical genetics null Not recorded viable no apparent phenotype C. albicans orf19.7391 ORF OCH1 CAL0004830 PMID: 16263704|CGD_REF: CAL0115362 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.7391 ORF OCH1 CAL0004830 PMID: 16263704|CGD_REF: CAL0115362 homozygous diploid, classical genetics null Not recorded protein/peptide modification: decreased Hex1p is under-glycosylated Hex1p C. albicans orf19.7391 ORF OCH1 CAL0004830 PMID: 16263704|CGD_REF: CAL0115362 heterozygous diploid, classical genetics repressible Not recorded protein/peptide modification: decreased decreased protein mannosylation mannosylated proteins C. albicans orf19.7391 ORF OCH1 CAL0004830 PMID: 16263704|CGD_REF: CAL0115362 heterozygous diploid, classical genetics repressible Not recorded protein activity: decreased decreased alpha-1,6-mannosyltransferase activity; decreased phosphomannan Och1p C. albicans orf19.7391 ORF OCH1 CAL0004830 PMID: 16263704|CGD_REF: CAL0115362 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased sodium dodecyl sulfate C. albicans orf19.7391 ORF OCH1 CAL0004830 PMID: 16263704|CGD_REF: CAL0115362 homozygous diploid, classical genetics null CAI-4 hyphal growth: abnormal Lee's or RPMI 1640 media mixed hyphal and pseudohyphal growth in response to hyphal induction by pH or temperature C. albicans orf19.7391 ORF OCH1 CAL0004830 PMID: 16263704|CGD_REF: CAL0115362 homozygous diploid, classical genetics null CAI-4 invasive growth: increased solid media C. albicans orf19.7391 ORF OCH1 CAL0004830 PMID: 16263704|CGD_REF: CAL0115362 homozygous diploid, classical genetics null Not recorded cell size: increased cells are enlarged and tend to aggregate C. albicans orf19.7391 ORF OCH1 CAL0004830 PMID: 16263704|CGD_REF: CAL0115362 homozygous diploid, classical genetics null Not recorded chemical compound accumulation: decreased phosphomannan C. albicans orf19.7391 ORF OCH1 CAL0004830 PMID: 16263704|CGD_REF: CAL0115362 homozygous diploid, classical genetics null Not recorded chitin deposition: increased increased cell wall chitin C. albicans orf19.7391 ORF OCH1 CAL0004830 PMID: 16263704|CGD_REF: CAL0115362 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased Congo Red C. albicans orf19.7391 ORF OCH1 CAL0004830 PMID: 16263704|CGD_REF: CAL0115362 homozygous diploid, classical genetics null Not recorded chemical compound accumulation: increased glucan increased cell wall glucan C. albicans orf19.7391 ORF OCH1 CAL0004830 PMID: 19222370|CGD_REF: CAL0122389 homozygous diploid, classical genetics null CAI-4 induction of host response: decreased Human peripheral blood mononuclear cells (PBMCs) stimulated with the mutant released significantly lower amounts of IL-1beta C. albicans orf19.7391 ORF OCH1 CAL0004830 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.7391 ORF OCH1 CAL0004830 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.7391 ORF OCH1 CAL0004830 PMID: 16263704|CGD_REF: CAL0115362 homozygous diploid, classical genetics null Not recorded virulence: decreased exhibits normal fungal burden in tissues mouse intravenous infection C. albicans orf19.7391 ORF OCH1 CAL0004830 PMID: 16263704|CGD_REF: CAL0115362 heterozygous diploid, classical genetics null Not recorded virulence: normal C. albicans orf19.7391 ORF OCH1 CAL0004830 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: decreased rate liquid synthetic complete medium C. albicans orf19.7391 ORF OCH1 CAL0004830 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.7392 ORF DED1 CAL0004832 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.7394 ORF GDA1 CAL0004837 PMID: 12455990|CGD_REF: CAL0081349 heterozygous diploid, classical genetics null Not recorded viable C. albicans orf19.7394 ORF GDA1 CAL0004837 PMID: 12455990|CGD_REF: CAL0081349 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.7394 ORF GDA1 CAL0004837 PMID: 12455990|CGD_REF: CAL0081349 homozygous diploid, classical genetics null Not recorded adhesion: normal adhesion to human epithelial (HeLa) cells C. albicans orf19.7394 ORF GDA1 CAL0004837 PMID: 12455990|CGD_REF: CAL0081349 homozygous diploid, classical genetics null CAI-4 hyphal growth: decreased induction by heat, pH, or solid Lee's medium plus mannitol C. albicans orf19.7394 ORF GDA1 CAL0004837 PMID: 12455990|CGD_REF: CAL0081349 homozygous diploid, classical genetics null CAI-4 hyphal growth: normal serum- or GlcNAc-containing media C. albicans orf19.7394 ORF GDA1 CAL0004837 PMID: 12455990|CGD_REF: CAL0081349 homozygous diploid, classical genetics null Not recorded cell wall morphology: abnormal C. albicans orf19.7396 ORF CAL0004843 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.7397 ORF CAL0004844 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: decreased growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.7397 ORF CAL0004844 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.7397 ORF CAL0004844 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.7397 ORF CAL0004844 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.740 ORF HAP41 CAL0001831 PMID: 18503007|CGD_REF: CAL0119016 homozygous diploid, classical genetics null Not recorded vegetative growth: normal rate solid YPG medium C. albicans orf19.740 ORF HAP41 CAL0001831 PMID: 18503007|CGD_REF: CAL0119016 heterozygous diploid, classical genetics null Not recorded viable C. albicans orf19.740 ORF HAP41 CAL0001831 PMID: 18503007|CGD_REF: CAL0119016 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.7400 ORF ALS7 CAL0005421 PMID: 17654269|CGD_REF: CAL0118166 homozygous diploid, classical genetics null Not recorded vegetative growth: decreased rate C. albicans orf19.7400 ORF ALS7 CAL0005421 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.7400 ORF ALS7 CAL0005421 PMID: 14663094|CGD_REF: CAL0080633 homozygous diploid, systematic mutation set (homozygous insertion mutants generated with URA3-ARG4-URA3 (UAU1) cassette) null BWP17 viable C. albicans orf19.7400 ORF ALS7 CAL0005421 PMID: 17654269|CGD_REF: CAL0118166 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.7400 ORF ALS7 CAL0005421 PMID: 17654269|CGD_REF: CAL0118166 homozygous diploid, classical genetics null Not recorded adhesion: increased adhesion to human vascular endothelial cell monolayers and buccal epithelial cells C. albicans orf19.7401 ORF ISW2 CAL0005422 PMID: 20041210|CGD_REF: CAL0124764 homozygous diploid, systematic mutation set null SN152 resistance to chemicals: decreased fluconazole severely sensitive C. albicans orf19.7401 ORF ISW2 CAL0005422 PMID: 14663094|CGD_REF: CAL0080633 homozygous diploid, systematic mutation set (homozygous insertion mutants generated with URA3-ARG4-URA3 (UAU1) cassette) null BWP17 viable C. albicans orf19.7401 ORF ISW2 CAL0005422 PMID: 16939537|CGD_REF: CAL0117180 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.7401 ORF ISW2 CAL0005422 PMID: 14663094|CGD_REF: CAL0080633 homozygous diploid, systematic mutation set (homozygous insertion mutants generated with URA3-ARG4-URA3 (UAU1) cassette) null BWP17 chlamydospore formation: absent C. albicans orf19.7401 ORF ISW2 CAL0005422 PMID: 20041210|CGD_REF: CAL0124764 homozygous diploid, systematic mutation set null SN152 colony appearance: abnormal YEPD medium at 37 deg C strongly decreased colony fuzziness and/or peripheral filamentation C. albicans orf19.7401 ORF ISW2 CAL0005422 PMID: 20041210|CGD_REF: CAL0124764 homozygous diploid, systematic mutation set null SN152 metal resistance: increased copper(2+) strongly resistant C. albicans orf19.7401 ORF ISW2 CAL0005422 PMID: 23856128|CGD_REF: CAL0000172540 homozygous diploid, classical genetics null BWP17 resistance to chemicals: decreased propolis C. albicans orf19.7402 ORF DOT1 CAL0005423 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.7402 ORF DOT1 CAL0005423 PMID: 19555456|CGD_REF: CAL0123821 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.7403 ORF CAL0005424 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.7404 ORF CAL0005425 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.7409 ORF ERV25 CAL0005428 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient YPD medium C. albicans orf19.7409 ORF ERV25 CAL0005428 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient YNB medium C. albicans orf19.7409 ORF ERV25 CAL0005428 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient SLAD medium C. albicans orf19.7410 ORF CYM1 CAL0005453 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.7410 ORF CYM1 CAL0005453 PMID: 14663094|CGD_REF: CAL0080633 homozygous diploid, systematic mutation set (homozygous insertion mutants generated with URA3-ARG4-URA3 (UAU1) cassette) null BWP17 viable C. albicans orf19.7411 ORF OAC1 CAL0005454 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.7412 ORF MUB1 CAL0005455 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.7412 ORF MUB1 CAL0005455 PMID: 14663094|CGD_REF: CAL0080633 homozygous diploid, systematic mutation set (homozygous insertion mutants generated with URA3-ARG4-URA3 (UAU1) cassette) null BWP17 viable C. albicans orf19.7412 ORF MUB1 CAL0005455 PMID: 23856128|CGD_REF: CAL0000172540 homozygous diploid, classical genetics null BWP17 resistance to chemicals: decreased propolis C. albicans orf19.7413 ORF MMS21 CAL0005456 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.7413 ORF MMS21 CAL0005456 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.7413 ORF MMS21 CAL0005456 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.7413 ORF MMS21 CAL0005456 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: decreased rate liquid synthetic complete medium C. albicans orf19.7413 ORF MMS21 CAL0005456 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient YNB medium C. albicans orf19.7413 ORF MMS21 CAL0005456 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.7414 ORF ALS6 CAL0005457 PMID: 17654269|CGD_REF: CAL0118166 homozygous diploid, classical genetics null Not recorded vegetative growth: decreased rate C. albicans orf19.7414 ORF ALS6 CAL0005457 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.7414 ORF ALS6 CAL0005457 PMID: 17654269|CGD_REF: CAL0118166 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.7414 ORF ALS6 CAL0005457 PMID: 17654269|CGD_REF: CAL0118166 homozygous diploid, classical genetics null Not recorded adhesion: increased adhesion to human vascular endothelial cell monolayers and buccal epithelial cells C. albicans orf19.7417 ORF TSA1 CAL0005458 PMID: 16102003|CGD_REF: CAL0114591 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased Calcofluor White solid Spider medium C. albicans orf19.7417 ORF TSA1 CAL0005458 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.7417 ORF TSA1 CAL0005458 PMID: 16102003|CGD_REF: CAL0114591 heterozygous diploid, classical genetics null Not recorded viable C. albicans orf19.7417 ORF TSA1 CAL0005458 PMID: 16102003|CGD_REF: CAL0114591 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.7417 ORF TSA1 CAL0005458 PMID: 18791036|CGD_REF: CAL0120270 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.7417 ORF TSA1 CAL0005458 PMID: 18791036|CGD_REF: CAL0120270 homozygous diploid, classical genetics null Not recorded hyphal growth: abnormal hydrogen peroxide increased induction of hyphal growth in response to H2O2 C. albicans orf19.7417 ORF TSA1 CAL0005458 PMID: 18791036|CGD_REF: CAL0120270 homozygous diploid, classical genetics null Not recorded inviable C. albicans orf19.7417 ORF TSA1 CAL0005458 PMID: 16102003|CGD_REF: CAL0114591 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased Congo Red solid Spider medium C. albicans orf19.7419 ORF HNT2 CAL0005459 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.742 ORF ALD6 CAL0001833 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.7420 ORF CAL0005486 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.7421 ORF CYP5 CAL0005487 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.7422 ORF CAL0005488 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.7424 ORF NSA2 CAL0005489 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.7427 ORF CAL0005492 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.7428 ORF APN1 CAL0005493 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.7428 ORF APN1 CAL0005493 PMID: 18667577|CGD_REF: CAL0119361 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.7433 ORF CAL0005513 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.7434 ORF GLG2 CAL0005514 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.7436 ORF AAF1 CAL0005516 PMID: 20041210|CGD_REF: CAL0124764 homozygous diploid, systematic mutation set null SN152 resistance to chemicals: increased fluconazole strongly resistant C. albicans orf19.7436 ORF AAF1 CAL0005516 PMID: 10377090|CGD_REF: CAL0080632 heterozygous diploid, classical genetics null Not recorded viable C. albicans orf19.7436 ORF AAF1 CAL0005516 PMID: 10377090|CGD_REF: CAL0080632 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.7436 ORF AAF1 CAL0005516 PMID: 10377090|CGD_REF: CAL0080632 heterozygous diploid, classical genetics null Not recorded adhesion: normal adhesion to human umbilical cord vein endothelial cells C. albicans orf19.7436 ORF AAF1 CAL0005516 PMID: 10377090|CGD_REF: CAL0080632 homozygous diploid, classical genetics null Not recorded adhesion: normal adhesion to human umbilical cord vein endothelial cells C. albicans orf19.7436 ORF AAF1 CAL0005516 PMID: 20041210|CGD_REF: CAL0124764 homozygous diploid, systematic mutation set null SN152 colony appearance: abnormal Spider medium slightly reduced colony wrinkling and enhanced peripheral filamentation C. albicans orf19.7436 ORF AAF1 CAL0005516 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: decreased growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.7436 ORF AAF1 CAL0005516 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: abnormal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.7436 ORF AAF1 CAL0005516 PMID: 10377090|CGD_REF: CAL0080632 heterozygous diploid, classical genetics null Not recorded virulence: decreased mouse intravenous infection C. albicans orf19.7436 ORF AAF1 CAL0005516 PMID: 10377090|CGD_REF: CAL0080632 homozygous diploid, classical genetics null Not recorded virulence: decreased mouse intravenous infection C. albicans orf19.7436 ORF AAF1 CAL0005516 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.7436 ORF AAF1 CAL0005516 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.7436.1 ORF ECM15 CAF0007123 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.7437 ORF CAL0005517 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.7437 ORF CAL0005517 PMID: 14507372|CGD_REF: CAL0088818 heterozygous diploid, large-scale survey (large-scale identification of essential genes by gene replacement and conditional expression (GRACE) method) repressible CAI-4 viable one allele is deleted and the other is placed under repressible Tet promoter C. albicans orf19.7438 ORF UBA1 CAL0005518 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.7438 ORF UBA1 CAL0005518 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient SC medium C. albicans orf19.744 ORF GDB1 CAL0001834 PMID: 20494978|CGD_REF: CAL0125636 heterozygous diploid, classical genetics null BWP17 resistance to chemicals: decreased clotrimazole (75 uM) growth in liquid culture confirmation of mutant phenotypes for heterozygous transposon insertion strains showing sensitivity in a large-scale assay C. albicans orf19.7440 ORF HST6 CAL0005538 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.7440 ORF HST6 CAL0005538 PMID: 21135205|CGD_REF: CAL0139967 heterozygous diploid, competitive growth (large-scale identification of genes essential for virulence in mouse) repressible CAI-4 virulence: normal mouse intravenous infection C. albicans orf19.7441 ORF CAL0005540 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.7444 ORF CAL0005547 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 invasive growth: decreased solid SLAD media C. albicans orf19.7445 ORF CAL0005550 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.7445 ORF CAL0005550 PMID: 21414038|CGD_REF: CAL0141808 homozygous diploid, classical genetics null BWP17 viable C. albicans orf19.7445 ORF CAL0005550 PMID: 21414038|CGD_REF: CAL0141808 homozygous diploid, classical genetics null BWP17 biofilm formation: normal C. albicans orf19.7446 ORF OPI3 CAL0005552 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.7447 ORF JEN1 CAL0005553 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.7447 ORF JEN1 CAL0005553 PMID: 14663094|CGD_REF: CAL0080633 homozygous diploid, systematic mutation set (homozygous insertion mutants generated with URA3-ARG4-URA3 (UAU1) cassette) null BWP17 viable C. albicans orf19.7447 ORF JEN1 CAL0005553 PMID: 15764370|CGD_REF: CAL0082247 heterozygous diploid, classical genetics null Not recorded viable C. albicans orf19.7447 ORF JEN1 CAL0005553 PMID: 15764370|CGD_REF: CAL0082247 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.7447 ORF JEN1 CAL0005553 PMID: 19968788|CGD_REF: CAL0124718 homozygous diploid, classical genetics null jen1::HIS1/jen1::ura3-, jen2::ura3-/jen2::URA3 RM1000 utilization of carbon source: decreased lactic acid C. albicans orf19.7447 ORF JEN1 CAL0005553 PMID: 19968788|CGD_REF: CAL0124718 homozygous diploid, classical genetics null jen1::HIS1/jen1::ura3-, jen2::ura3-/jen2::URA3 RM1000 utilization of carbon source: decreased pyruvic acid C. albicans orf19.7448 ORF LYS9 CAL0005555 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.7449 ORF CAL0005557 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.745 ORF VAC8 CAL0001835 PMID: 19040629|CGD_REF: CAL0121263 heterozygous diploid, classical genetics repressible CAI-4 filamentous growth: abnormal agar-slide cultures with serum forms pseudohyphae instead of true hyphae C. albicans orf19.745 ORF VAC8 CAL0001835 PMID: 16467476|CGD_REF: CAL0115524 homozygous diploid, classical genetics null Not recorded vacuolar distribution: abnormal vacuolar inheritance defect C. albicans orf19.745 ORF VAC8 CAL0001835 PMID: 19040629|CGD_REF: CAL0121263 heterozygous diploid, classical genetics repressible Not recorded vacuolar morphology: abnormal decreased vacuole content C. albicans orf19.745 ORF VAC8 CAL0001835 PMID: 19040629|CGD_REF: CAL0121263 heterozygous diploid, classical genetics repressible Not recorded vacuolar morphology: abnormal enlarged vacuoles, depleted in emerging buds in yeast-like cells C. albicans orf19.745 ORF VAC8 CAL0001835 PMID: 16467476|CGD_REF: CAL0115524 homozygous diploid, classical genetics null Not recorded vacuolar morphology: abnormal vacuoles are fragmented C. albicans orf19.745 ORF VAC8 CAL0001835 PMID: 16467476|CGD_REF: CAL0115524 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.745 ORF VAC8 CAL0001835 PMID: 19040629|CGD_REF: CAL0121263 heterozygous diploid, classical genetics repressible CAI-4 hyphal growth: abnormal altered branching frequency in hyphae C. albicans orf19.745 ORF VAC8 CAL0001835 PMID: 16467476|CGD_REF: CAL0115524 homozygous diploid, classical genetics null CAI-4 hyphal growth: abnormal increased hyphal branching C. albicans orf19.7451 ORF FUN31 CAL0005577 PMID: 18434592|CGD_REF: CAL0118971 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased caspofungin C. albicans orf19.7451 ORF FUN31 CAL0005577 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.7451 ORF FUN31 CAL0005577 PMID: 14663094|CGD_REF: CAL0080633 homozygous diploid, systematic mutation set (homozygous insertion mutants generated with URA3-ARG4-URA3 (UAU1) cassette) null BWP17 viable C. albicans orf19.7451 ORF FUN31 CAL0005577 PMID: 18434592|CGD_REF: CAL0118971 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.7453 ORF CAL0005581 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient YPD medium C. albicans orf19.7453 ORF CAL0005581 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient SC medium C. albicans orf19.7453 ORF CAL0005581 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient YNB medium C. albicans orf19.7453 ORF CAL0005581 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient SLAD medium C. albicans orf19.7454 ORF TAF60 CAL0005584 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.7454 ORF TAF60 CAL0005584 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, competitive growth (haploinsufficient phenotype assay, barcode deletion set) null SC5314 resistance to chemicals: decreased amphotericin B C. albicans orf19.7454 ORF TAF60 CAL0005584 PMID: 21135205|CGD_REF: CAL0139967 heterozygous diploid, large-scale survey (large-scale identification of genes essential for virulence in mouse) repressible CAI-4 virulence: absent mouse intravenous infection C. albicans orf19.7459 ORF CAL0005593 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.7459 ORF CAL0005593 PMID: 21414038|CGD_REF: CAL0141808 homozygous diploid, classical genetics null BWP17 viable C. albicans orf19.7463 ORF CAL0005620 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.7464 ORF CAL0005624 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, competitive growth (haploinsufficient phenotype assay, barcode deletion set) null SC5314 resistance to chemicals: decreased ergosterol analogs (ECC69 and/or ECC1384) C. albicans orf19.7464 ORF CAL0005624 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.7466 ORF ACC1 CAL0005630 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.7469 ORF ARG1 CAL0005634 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.7469 ORF ARG1 CAL0005634 PMID: 6358187|CGD_REF: CAL0080660 unknown ploidy, classical genetics unspecified Other C. albicans auxotrophy arginine C. albicans orf19.7469 ORF ARG1 CAL0005634 PMID: 6358187|CGD_REF: CAL0080660 unknown ploidy, classical genetics unspecified Other C. albicans viable C. albicans orf19.747 ORF NBP35 CAL0001838 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.7472 ORF IFF4 CAL0005658 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.7472 ORF IFF4 CAL0005658 PMID: 14663094|CGD_REF: CAL0080633 homozygous diploid, systematic mutation set (homozygous insertion mutants generated with URA3-ARG4-URA3 (UAU1) cassette) null BWP17 viable C. albicans orf19.7472 ORF IFF4 CAL0005658 PMID: 17481864|CGD_REF: CAL0118153 homozygous diploid, classical genetics null BWP17 viable C. albicans orf19.7472 ORF IFF4 CAL0005658 PMID: 17481864|CGD_REF: CAL0118153 homozygous diploid, classical genetics null Not recorded adhesion: abnormal germ tubes display altered adhesion to plastic C. albicans orf19.7472 ORF IFF4 CAL0005658 PMID: 17481864|CGD_REF: CAL0118153 homozygous diploid, classical genetics null Not recorded adhesion: decreased adhesion of germ tubes to plastic C. albicans orf19.7472 ORF IFF4 CAL0005658 PMID: 18178776|CGD_REF: CAL0118769 heterozygous diploid, classical genetics overexpression Not recorded adhesion: increased adhesion to plastic and to human epithelial cells C. albicans orf19.7472 ORF IFF4 CAL0005658 PMID: 19347602|CGD_REF: CAL0122742 homozygous diploid, classical genetics null BWP17 adhesion: decreased adhesion to silicone catheter C. albicans orf19.7472 ORF IFF4 CAL0005658 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.7472 ORF IFF4 CAL0005658 PMID: 18178776|CGD_REF: CAL0118769 heterozygous diploid, classical genetics overexpression HIS1-TR-IFF4 (tetracycline repressible promoter) Other C. albicans resistance to killing by host cells: decreased approximately 60% of the IFF4-overexpressing strains killed compared to about 40% killing in wild-type controls in vitro model of infection (human neutrophils) C. albicans orf19.7472 ORF IFF4 CAL0005658 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.7472 ORF IFF4 CAL0005658 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.7472 ORF IFF4 CAL0005658 PMID: 18178776|CGD_REF: CAL0118769 heterozygous diploid, classical genetics overexpression Not recorded virulence: normal immunosuppressed mouse intravenous infection C. albicans orf19.7472 ORF IFF4 CAL0005658 PMID: 18178776|CGD_REF: CAL0118769 heterozygous diploid, classical genetics overexpression Not recorded virulence: decreased mouse intravenous infection C. albicans orf19.7472 ORF IFF4 CAL0005658 PMID: 19347602|CGD_REF: CAL0122742 homozygous diploid, classical genetics null Not recorded virulence: decreased mouse intravenous infection C. albicans orf19.7472 ORF IFF4 CAL0005658 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.7473 ORF CAL0005661 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 invasive growth: decreased solid SLAD media C. albicans orf19.7475 ORF PHO81 CAL0005667 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.7475 ORF PHO81 CAL0005667 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.7475 ORF PHO81 CAL0005667 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: abnormal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.7475 ORF PHO81 CAL0005667 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.7475 ORF PHO81 CAL0005667 PMID: 20965180|CGD_REF: CAL0137819 homozygous diploid, classical genetics null pho81::hisG-URA3-hisG/pho81::hisG CAI-4 viable C. albicans orf19.7475 ORF PHO81 CAL0005667 PMID: 20965180|CGD_REF: CAL0137819 homozygous diploid, classical genetics null pho81::hisG-URA3-hisG/pho81::hisG CAI-4 filamentous growth: increased YPD medium C. albicans orf19.7475 ORF PHO81 CAL0005667 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.7477 ORF YRB1 CAL0005670 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.7478 ORF CAL0005672 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.7479 ORF NTH1 CAL0005674 PMID: 9421900|CGD_REF: CAL0081608 homozygous diploid, classical genetics null CAI-4 germ tube formation: delayed serum- or GlcNAc-containing media C. albicans orf19.7479 ORF NTH1 CAL0005674 PMID: 9421900|CGD_REF: CAL0081608 heterozygous diploid, classical genetics null Not recorded thermotolerance: decreased heat shock at 50 deg C decreased ability to recover from heat shock C. albicans orf19.7479 ORF NTH1 CAL0005674 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.7479 ORF NTH1 CAL0005674 PMID: 14663094|CGD_REF: CAL0080633 homozygous diploid, systematic mutation set (homozygous insertion mutants generated with URA3-ARG4-URA3 (UAU1) cassette) null BWP17 viable C. albicans orf19.7479 ORF NTH1 CAL0005674 PMID: 14507372|CGD_REF: CAL0088818 heterozygous diploid, large-scale survey (large-scale identification of essential genes by gene replacement and conditional expression (GRACE) method) repressible CAI-4 viable one allele is deleted and the other is placed under repressible Tet promoter C. albicans orf19.7479 ORF NTH1 CAL0005674 PMID: 9421900|CGD_REF: CAL0081608 heterozygous diploid, classical genetics null Not recorded viable C. albicans orf19.7479 ORF NTH1 CAL0005674 PMID: 9421900|CGD_REF: CAL0081608 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.7479 ORF NTH1 CAL0005674 PMID: 16423071|CGD_REF: CAL0115414 homozygous diploid, classical genetics null Not recorded oxidative stress resistance: increased hydrogen peroxide C. albicans orf19.7479 ORF NTH1 CAL0005674 PMID: 9421900|CGD_REF: CAL0081608 heterozygous diploid, classical genetics null Not recorded utilization of carbon source: decreased trehalose slight decrease C. albicans orf19.7479 ORF NTH1 CAL0005674 PMID: 9421900|CGD_REF: CAL0081608 homozygous diploid, classical genetics null Not recorded utilization of carbon source: decreased trehalose slight decrease C. albicans orf19.7479 ORF NTH1 CAL0005674 PMID: 9421900|CGD_REF: CAL0081608 heterozygous diploid, classical genetics null Not recorded virulence: normal mouse intravenous infection C. albicans orf19.7479 ORF NTH1 CAL0005674 PMID: 9421900|CGD_REF: CAL0081608 homozygous diploid, classical genetics null Not recorded virulence: normal mouse intravenous infection C. albicans orf19.7483 ORF CRM1 CAL0005701 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.7484 ORF ADE1 CAL0005704 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.7484 ORF ADE1 CAL0005704 PMID: 6754707|CGD_REF: CAL0082625 unknown ploidy, classical genetics unspecified Other C. albicans auxotrophy adenine recessive mutation; later papers mention that this strain contains ade1-1 allele C. albicans orf19.7484 ORF ADE1 CAL0005704 PMID: 6358187|CGD_REF: CAL0080660 unknown ploidy, classical genetics unspecified Other C. albicans auxotrophy adenine C. albicans orf19.7484 ORF ADE1 CAL0005704 PMID: 6358187|CGD_REF: CAL0080660 unknown ploidy, classical genetics unspecified Other C. albicans colony color: abnormal colonies are red C. albicans orf19.7484 ORF ADE1 CAL0005704 PMID: 6754707|CGD_REF: CAL0082625 unknown ploidy, classical genetics unspecified ade1-1 Other C. albicans colony color: abnormal red colonies; later papers mention that this strain contains ade1-1 allele C. albicans orf19.7484 ORF ADE1 CAL0005704 PMID: 2050413|CGD_REF: CAL0080658 unknown ploidy, classical genetics unspecified Other C. albicans auxotrophy adenine C. albicans orf19.7484 ORF ADE1 CAL0005704 PMID: 2050413|CGD_REF: CAL0080658 unknown ploidy, classical genetics unspecified Other C. albicans viable C. albicans orf19.7484 ORF ADE1 CAL0005704 PMID: 6358187|CGD_REF: CAL0080660 unknown ploidy, classical genetics unspecified Other C. albicans viable C. albicans orf19.7484 ORF ADE1 CAL0005704 PMID: 8195090|CGD_REF: CAL0080662 unknown ploidy, classical genetics unspecified Other C. albicans viable adenine C. albicans orf19.7484 ORF ADE1 CAL0005704 PMID: 6754707|CGD_REF: CAL0082625 unknown ploidy, classical genetics unspecified ade1-1 Other C. albicans viable later papers mention that this strain contains ade1-1 allele C. albicans orf19.7485 ORF CAL0005707 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.7486 ORF MRPL6 CAL0005711 PMID: 21135205|CGD_REF: CAL0139967 heterozygous diploid, large-scale survey (large-scale identification of genes essential for virulence in mouse) repressible CAI-4 virulence: absent mouse intravenous infection C. albicans orf19.7487 ORF CAL0005713 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient SLAD medium C. albicans orf19.7488 ORF CAL0005715 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.7489 ORF CAL0005717 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.7490 ORF CAL0005731 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.7491 ORF RTT109 CAL0005733 PMID: 20080646|CGD_REF: CAL0124778 homozygous diploid, classical genetics null SC5314 viable C. albicans orf19.7491 ORF RTT109 CAL0005733 PMID: 20080646|CGD_REF: CAL0124778 homozygous diploid, classical genetics null SC5314 colony appearance: abnormal wrinkled colonies C. albicans orf19.7491 ORF RTT109 CAL0005733 PMID: 20080646|CGD_REF: CAL0124778 homozygous diploid, classical genetics null SC5314 filamentous growth: increased standard growth conditions large proportion of filamentous cells C. albicans orf19.7491 ORF RTT109 CAL0005733 PMID: 20080646|CGD_REF: CAL0124778 homozygous diploid, classical genetics null SC5314 resistance to chemicals: decreased campthotecin C. albicans orf19.7491 ORF RTT109 CAL0005733 PMID: 20080646|CGD_REF: CAL0124778 homozygous diploid, classical genetics null SC5314 resistance to chemicals: decreased methyl methanesulfonate C. albicans orf19.7491 ORF RTT109 CAL0005733 PMID: 20080646|CGD_REF: CAL0124778 homozygous diploid, classical genetics null SC5314 resistance to chemicals: decreased hydrogen peroxide C. albicans orf19.7491 ORF RTT109 CAL0005733 PMID: 20080646|CGD_REF: CAL0124778 homozygous diploid, classical genetics null SC5314 resistance to chemicals: decreased flucytosine C. albicans orf19.7491 ORF RTT109 CAL0005733 PMID: 20080646|CGD_REF: CAL0124778 homozygous diploid, classical genetics null SC5314 virulence: decreased mouse intravenous infection C. albicans orf19.7491 ORF RTT109 CAL0005733 PMID: 20080646|CGD_REF: CAL0124778 homozygous diploid, classical genetics null SC5314 virulence: decreased in vitro model of infection C. albicans orf19.7491 ORF RTT109 CAL0005733 PMID: 20601951|CGD_REF: CAL0125877 homozygous diploid, classical genetics null SN152 induction of host response: decreased mutant induced lower amounts of interleukin-6 and keratinocyte-derived chemokine mouse intravenous infection (A/J mice) C. albicans orf19.7491 ORF RTT109 CAL0005733 PMID: 20080646|CGD_REF: CAL0124778 homozygous diploid, classical genetics null Other C. albicans resistance to killing by host cells: decreased in vitro model of infection (ZBM2, mouse-derived macrophage-like cell line) C. albicans orf19.7491 ORF RTT109 CAL0005733 PMID: 21749487|CGD_REF: CAL0000142507 homozygous diploid, classical genetics null rtt109::FRT/rtt109::FRT SC5314 phenotypic switching: decreased reduced spontaneous opaque cell-type formation compared with the wild-type alpha/alpha strain C. albicans orf19.7491 ORF RTT109 CAL0005733 PMID: 20601951|CGD_REF: CAL0125877 homozygous diploid, classical genetics null SN152 resistance to chemicals: decreased hydroxyurea (10 mM) C. albicans orf19.7491 ORF RTT109 CAL0005733 PMID: 20601951|CGD_REF: CAL0125877 homozygous diploid, classical genetics null SN152 resistance to chemicals: decreased methyl methanesulfonate (0.005%) C. albicans orf19.7491 ORF RTT109 CAL0005733 PMID: 20601951|CGD_REF: CAL0125877 homozygous diploid, classical genetics null SN152 resistance to chemicals: decreased caspofungin (0.03 micrograms/ml) C. albicans orf19.7491 ORF RTT109 CAL0005733 PMID: 20601951|CGD_REF: CAL0125877 homozygous diploid, classical genetics null SN152 resistance to chemicals: decreased micafungin (0.02 micrograms/ml) growth partially restored by the addition of antioxidants (25 mM N-acetyl-L-cysteine or vitamin C) C. albicans orf19.7491 ORF RTT109 CAL0005733 PMID: 20601951|CGD_REF: CAL0125877 homozygous diploid, classical genetics null SN152 virulence: decreased reduced fungal burden in the heart and kidneys compared to control strains; a weaker inflammatory response is illicited mouse intravenous infection (A/J mice) C. albicans orf19.7492 ORF SWC4 CAL0005735 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.7495 ORF CAL0005744 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.7497 ORF CAL0005748 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.7497 ORF CAL0005748 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.7497 ORF CAL0005748 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.7497 ORF CAL0005748 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.7498 ORF LEU1 CAL0005750 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.7499 ORF CAL0005752 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.7500 ORF PXA1 CAL0006350 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.7501 ORF NAP1 CAL0006351 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.7501 ORF NAP1 CAL0006351 PMID: 24496790|CGD_REF: CAL0000173769 homozygous diploid, classical genetics null BWP17 viable C. albicans orf19.7501 ORF NAP1 CAL0006351 PMID: 24496790|CGD_REF: CAL0000173769 homozygous diploid, classical genetics null BWP17 filamentous growth: abnormal C. albicans orf19.7503 ORF CDA2 CAL0006353 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.7503 ORF CDA2 CAL0006353 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.7503 ORF CDA2 CAL0006353 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.7503 ORF CDA2 CAL0006353 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.751 ORF CAL0001861 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.751 ORF CAL0001861 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.751 ORF CAL0001861 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.751 ORF CAL0001861 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.7510 ORF KIN2 CAL0006385 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.7510 ORF KIN2 CAL0006385 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.7510 ORF KIN2 CAL0006385 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.7510 ORF KIN2 CAL0006385 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.7510 ORF KIN2 CAL0006385 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.7511 ORF CAL0006386 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.7511 ORF CAL0006386 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient YPD medium C. albicans orf19.7511 ORF CAL0006386 PMID: 21135205|CGD_REF: CAL0139967 heterozygous diploid, large-scale survey (large-scale identification of genes essential for virulence in mouse) repressible CAI-4 virulence: absent mouse intravenous infection C. albicans orf19.7512 ORF CAL0006387 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.7513 ORF ALK2 CAL0006388 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.7514 ORF PCK1 CAL0006389 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.7514 ORF PCK1 CAL0006389 PMID: 16681837|CGD_REF: CAL0116091 homozygous diploid, classical genetics null Not recorded virulence: decreased mouse intravenous infection C. albicans orf19.7516 ORF CAL0006390 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.7516 ORF CAL0006390 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.7516 ORF CAL0006390 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.7516 ORF CAL0006390 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.7516 ORF CAL0006390 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.7517 ORF CHT1 CAL0006391 PMID: 16214381|CGD_REF: CAL0114979 homozygous diploid, classical genetics null BWP17 filamentous growth: increased increased filamentation at colony periphery C. albicans orf19.7517 ORF CHT1 CAL0006391 PMID: 16214381|CGD_REF: CAL0114979 homozygous diploid, classical genetics null BWP17 germ tube formation: normal serum-containing medium C. albicans orf19.7517 ORF CHT1 CAL0006391 PMID: 16214381|CGD_REF: CAL0114979 heterozygous diploid, classical genetics null Not recorded viable C. albicans orf19.7517 ORF CHT1 CAL0006391 PMID: 16214381|CGD_REF: CAL0114979 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.7517 ORF CHT1 CAL0006391 PMID: 18765290|CGD_REF: CAL0119430 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.7518 ORF ZCF38 CAL0006392 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.7518 ORF ZCF38 CAL0006392 PMID: 15964282|CGD_REF: CAL0114274 homozygous diploid, systematic mutation set (split-marker transposon insertion strategy to disrupt both alleles) null BWP17 viable C. albicans orf19.7518 ORF ZCF38 CAL0006392 PMID: 19463063|CGD_REF: CAL0123630 homozygous diploid, systematic mutation set (split-marker transposon insertion strategy to disrupt both alleles) null BWP17 viable C. albicans orf19.7518 ORF ZCF38 CAL0006392 PMID: 15964282|CGD_REF: CAL0114274 homozygous diploid, systematic mutation set (split-marker transposon insertion strategy to disrupt both alleles) null BWP17 biofilm formation: normal C. albicans orf19.7518 ORF ZCF38 CAL0006392 PMID: 19463063|CGD_REF: CAL0123630 homozygous diploid, systematic mutation set (split-marker transposon insertion strategy to disrupt both alleles) null BWP17 virulence: normal Toll mutant D. melanogaster invasive infection insect infection C. albicans orf19.7518 ORF ZCF38 CAL0006392 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 invasive growth: decreased solid SLAD media C. albicans orf19.7520 ORF POT1 CAL0006419 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.7520 ORF POT1 CAL0006419 PMID: 23758791|CGD_REF: CAL0000172382 homozygous diploid, classical genetics null SC5314 viable C. albicans orf19.7520 ORF POT1 CAL0006419 PMID: 23758791|CGD_REF: CAL0000172382 homozygous diploid, classical genetics null SC5314 utilization of carbon source: decreased fatty acid C. albicans orf19.7520 ORF POT1 CAL0006419 PMID: 23758791|CGD_REF: CAL0000172382 homozygous diploid, classical genetics null SC5314 virulence: normal other model (chicken embryo) C. albicans orf19.7521 ORF REP1 CAL0000001 PMID: 19527793|CGD_REF: CAL0123759 homozygous diploid, classical genetics null Not recorded resistance to chemicals: increased miconazole C. albicans orf19.7521 ORF REP1 CAL0000001 PMID: 19527793|CGD_REF: CAL0123759 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.7521 ORF REP1 CAL0000001 PMID: 19527793|CGD_REF: CAL0123759 homozygous diploid, classical genetics null Not recorded resistance to chemicals: increased voriconazole C. albicans orf19.7521 ORF REP1 CAL0000001 PMID: 19527793|CGD_REF: CAL0123759 homozygous diploid, classical genetics null Not recorded resistance to chemicals: increased fluconazole C. albicans orf19.7522 ORF CAL0000002 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.7522 ORF CAL0000002 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, competitive growth (haploinsufficient phenotype assay, barcode deletion set) null SC5314 resistance to chemicals: decreased amphotericin B C. albicans orf19.7523 ORF MKC1 CAL0000003 PMID: 15800048|CGD_REF: CAL0104040 homozygous diploid, classical genetics null CAI-4 filamentous growth: normal liquid media C. albicans orf19.7523 ORF MKC1 CAL0000003 PMID: 9493378|CGD_REF: CAL0081538 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased nikkomycin Z C. albicans orf19.7523 ORF MKC1 CAL0000003 PMID: 16304189|CGD_REF: CAL0114223 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased caspofungin paradoxical effect of supra-MIC caspofungin (whereby high concentrations are less effective than lower concentrations of the antifungal) is decreased C. albicans orf19.7523 ORF MKC1 CAL0000003 PMID: 7891715|CGD_REF: CAL0081536 heterozygous diploid, classical genetics null Not recorded resistance to enzymatic treatment: decreased glusulase phenotype is intermediate between that of wild type and the homozygous null mutant C. albicans orf19.7523 ORF MKC1 CAL0000003 PMID: 7891715|CGD_REF: CAL0081536 homozygous diploid, classical genetics null Not recorded resistance to enzymatic treatment: decreased glusulase C. albicans orf19.7523 ORF MKC1 CAL0000003 PMID: 9493378|CGD_REF: CAL0081538 homozygous diploid, classical genetics null Not recorded thermotolerance: decreased defective acquisition of thermotolerance C. albicans orf19.7523 ORF MKC1 CAL0000003 PMID: 7891715|CGD_REF: CAL0081536 heterozygous diploid, classical genetics null Not recorded heat sensitivity: increased loss of viability at high temperature C. albicans orf19.7523 ORF MKC1 CAL0000003 PMID: 7891715|CGD_REF: CAL0081536 homozygous diploid, classical genetics null Not recorded heat sensitivity: increased C. albicans orf19.7523 ORF MKC1 CAL0000003 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.7523 ORF MKC1 CAL0000003 PMID: 7891715|CGD_REF: CAL0081536 heterozygous diploid, classical genetics null Not recorded viable C. albicans orf19.7523 ORF MKC1 CAL0000003 PMID: 7891715|CGD_REF: CAL0081536 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.7523 ORF MKC1 CAL0000003 PMID: 9009353|CGD_REF: CAL0081537 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.7523 ORF MKC1 CAL0000003 PMID: 19187560|CGD_REF: CAL0122338 homozygous diploid, classical genetics null SC5314 biofilm formation: abnormal forms biofilm with altered detachment properties C. albicans orf19.7523 ORF MKC1 CAL0000003 PMID: 9493378|CGD_REF: CAL0081538 homozygous diploid, classical genetics null CAI-4 hyphal growth: decreased Spider medium C. albicans orf19.7523 ORF MKC1 CAL0000003 PMID: 15800048|CGD_REF: CAL0104040 homozygous diploid, classical genetics null CAI-4 invasive growth: decreased severely decreased agar-invasive or agar-embedded filamentation C. albicans orf19.7523 ORF MKC1 CAL0000003 PMID: 15800048|CGD_REF: CAL0104040 heterozygous diploid, classical genetics null CAI-4 invasive growth: normal C. albicans orf19.7523 ORF MKC1 CAL0000003 PMID: 9493378|CGD_REF: CAL0081538 homozygous diploid, classical genetics null Not recorded cell wall morphology: abnormal C. albicans orf19.7523 ORF MKC1 CAL0000003 PMID: 16179009|CGD_REF: CAL0114738 homozygous diploid, classical genetics null Not recorded oxidative stress resistance: decreased 3-morpholinosydnonimine 3-morpholinosydnonimine (SIN1-1) generates nitric oxide, superoxide, and peroxynitrite C. albicans orf19.7523 ORF MKC1 CAL0000003 PMID: 16079350|CGD_REF: CAL0114435 homozygous diploid, classical genetics null Not recorded oxidative stress resistance: decreased diamide mutant does not display sensitivity to other oxidizing agents C. albicans orf19.7523 ORF MKC1 CAL0000003 PMID: 7891715|CGD_REF: CAL0081536 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased caffeine C. albicans orf19.7523 ORF MKC1 CAL0000003 PMID: 15800048|CGD_REF: CAL0104040 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased fluconazole adherence-induced fluconazole resistance is decreased C. albicans orf19.7523 ORF MKC1 CAL0000003 PMID: 16179009|CGD_REF: CAL0114738 homozygous diploid, classical genetics null SC5314 induction of host response: abnormal mutant cell wall extract causes greater induction of nitric oxide release from cultured RAW 264.7 macrophages, compared to wild-type cell wall extract C. albicans orf19.7523 ORF MKC1 CAL0000003 PMID: 16179009|CGD_REF: CAL0114738 homozygous diploid, classical genetics null SC5314 resistance to killing by host cells: decreased decreased survival in the presence of neutrophils or activated macrophages in vitro model of infection (mouse neutrophils or macrophages) C. albicans orf19.7523 ORF MKC1 CAL0000003 PMID: 21407800|CGD_REF: CAL0141800 homozygous diploid, large-scale survey null BWP17 interaction with host/environment: abnormal significantly reduced damage to epithelial cells, but normal adhesion and invasion ex vivo model of infection C. albicans orf19.7523 ORF MKC1 CAL0000003 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.7523 ORF MKC1 CAL0000003 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.7523 ORF MKC1 CAL0000003 PMID: 9493378|CGD_REF: CAL0081538 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.7523 ORF MKC1 CAL0000003 PMID: 15800048|CGD_REF: CAL0104040 homozygous diploid, competitive growth null CAI-4 biofilm formation: abnormal on polystyrene C. albicans orf19.7523 ORF MKC1 CAL0000003 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.7523 ORF MKC1 CAL0000003 PMID: 9009353|CGD_REF: CAL0081537 homozygous diploid, classical genetics null Not recorded virulence: decreased exhibits decreased kidney colonization mouse intravenous infection C. albicans orf19.7523 ORF MKC1 CAL0000003 PMID: 20140194|CGD_REF: CAL0124995 homozygous diploid, classical genetics null Other C. albicans resistance to chemicals: decreased caspofungin C. albicans orf19.7523 ORF MKC1 CAL0000003 PMID: 20870881|CGD_REF: CAL0126465 homozygous diploid, classical genetics null SC5314 mating efficiency: decreased C. albicans orf19.7523 ORF MKC1 CAL0000003 PMID: 20865172|CGD_REF: CAL0126252 homozygous diploid, classical genetics null SN95 resistance to chemicals: decreased terbinafine C. albicans orf19.7523 ORF MKC1 CAL0000003 PMID: 20865172|CGD_REF: CAL0126252 homozygous diploid, classical genetics null SN95 resistance to chemicals: decreased fenpropimorph C. albicans orf19.7523 ORF MKC1 CAL0000003 PMID: 20865172|CGD_REF: CAL0126252 homozygous diploid, classical genetics null SN95 resistance to chemicals: decreased fluconazole C. albicans orf19.7523 ORF MKC1 CAL0000003 PMID: 20140194|CGD_REF: CAL0124995 homozygous diploid, classical genetics null Other C. albicans viable caspofungin C. albicans orf19.7523 ORF MKC1 CAL0000003 PMID: 20140194|CGD_REF: CAL0124995 homozygous diploid, classical genetics null Other C. albicans viable C. albicans orf19.7523 ORF MKC1 CAL0000003 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.7529 ORF EPL1 CAL0000005 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.7529 ORF EPL1 CAL0000005 PMID: 21135205|CGD_REF: CAL0139967 heterozygous diploid, large-scale survey (large-scale identification of genes essential for virulence in mouse) repressible CAI-4 virulence: absent mouse intravenous infection C. albicans orf19.753 ORF MNN15 CAL0001863 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: increased growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.753 ORF MNN15 CAL0001863 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.753 ORF MNN15 CAL0001863 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.753 ORF MNN15 CAL0001863 PMID: 23886038|CGD_REF: CAL0000172548 homozygous diploid, classical genetics null CAI-4 viable C. albicans orf19.753 ORF MNN15 CAL0001863 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.7534 ORF MIS12 CAL0000024 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.7537 ORF BNR1 CAL0000025 PMID: 15914538|CGD_REF: CAL0114281 heterozygous diploid, classical genetics repressible Not recorded actin cytoskeleton morphology: abnormal delocalized actin patches C. albicans orf19.7537 ORF BNR1 CAL0000025 PMID: 16215178|CGD_REF: CAL0114839 homozygous diploid, classical genetics null Not recorded cell shape: abnormal cells are elongated C. albicans orf19.7537 ORF BNR1 CAL0000025 PMID: 16215178|CGD_REF: CAL0114839 homozygous diploid, classical genetics null Not recorded cytokinesis: absent C. albicans orf19.7537 ORF BNR1 CAL0000025 PMID: 15914538|CGD_REF: CAL0114281 homozygous diploid, classical genetics null Not recorded viable no apparent phenotype C. albicans orf19.7537 ORF BNR1 CAL0000025 PMID: 15914538|CGD_REF: CAL0114281 heterozygous diploid, classical genetics null Not recorded viable C. albicans orf19.7537 ORF BNR1 CAL0000025 PMID: 16215178|CGD_REF: CAL0114839 heterozygous diploid, classical genetics null Not recorded viable C. albicans orf19.7537 ORF BNR1 CAL0000025 PMID: 16215178|CGD_REF: CAL0114839 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.7538 ORF CAL0000026 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.7539 ORF INO2 CAL0000027 PMID: 17588177|CGD_REF: CAL0118322 homozygous diploid, classical genetics null Not recorded inviable homozygous null mutant strain could not be recovered, suggesting that the gene is essential under the selection conditions C. albicans orf19.754 ORF YBN5 CAL0001864 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.7546 ORF CAL0000056 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.7548 ORF MED21 CAL0000060 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.7549 ORF PMT5 CAL0000061 PMID: 15659169|CGD_REF: CAL0082300 homozygous diploid, classical genetics null CAI-4 hyphal growth: normal Lee's, Spider, and serum-containing media C. albicans orf19.7549 ORF PMT5 CAL0000061 PMID: 17885949|CGD_REF: CAL0118767 homozygous diploid, classical genetics null CAI-4 induction of host response: increased thioglycollate induced murine peritoneal macrophages significantly higher IL-10 levels induced by mutant C. albicans orf19.7549 ORF PMT5 CAL0000061 PMID: 17885949|CGD_REF: CAL0118767 heterozygous diploid, classical genetics null CAI-4 induction of host response: increased murine macrophages prolonged activation of MyD88 C. albicans orf19.7549 ORF PMT5 CAL0000061 PMID: 17885949|CGD_REF: CAL0118767 homozygous diploid, classical genetics null CAI-4 resistance to killing by host cells: increased in vitro model of infection (thioglycollate induced macrophages) C. albicans orf19.7549 ORF PMT5 CAL0000061 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.7549 ORF PMT5 CAL0000061 PMID: 15659169|CGD_REF: CAL0082300 heterozygous diploid, classical genetics null Not recorded viable C. albicans orf19.7549 ORF PMT5 CAL0000061 PMID: 15659169|CGD_REF: CAL0082300 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.7549 ORF PMT5 CAL0000061 PMID: 17005840|CGD_REF: CAL0116746 homozygous diploid, classical genetics null CAF2-1 biofilm formation: normal C. albicans orf19.7549 ORF PMT5 CAL0000061 PMID: 15659169|CGD_REF: CAL0082300 homozygous diploid, classical genetics null Not recorded virulence: normal mouse intravenous infection C. albicans orf19.7550 ORF IFA14 CAL0000081 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.7550 ORF IFA14 CAL0000081 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.7550 ORF IFA14 CAL0000081 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.7550 ORF IFA14 CAL0000081 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.7551 ORF ALO1 CAL0000083 PMID: 18282465|CGD_REF: CAL0118812 aneuploid, classical genetics overexpression Not recorded respiratory growth: abnormal decreased lag phase in presence of cyanide; increased respiration and AOX protein abundance C. albicans orf19.7551 ORF ALO1 CAL0000083 PMID: 18282465|CGD_REF: CAL0118812 homozygous diploid, classical genetics null Not recorded respiratory growth: abnormal decreased respiration and increased lag phase in presence of cyanide, indicating defect in AOX-mediated cyanide-insensitive respiratory growth C. albicans orf19.7551 ORF ALO1 CAL0000083 PMID: 11349062|CGD_REF: CAL0080715 homozygous diploid, classical genetics null Not recorded hyphal growth: decreased solid Spider medium severe decrease C. albicans orf19.7551 ORF ALO1 CAL0000083 PMID: 11349062|CGD_REF: CAL0080715 heterozygous diploid, classical genetics null Not recorded hyphal growth: decreased solid Spider medium slight decrease C. albicans orf19.7551 ORF ALO1 CAL0000083 PMID: 11349062|CGD_REF: CAL0080715 homozygous diploid, classical genetics null Not recorded oxidative stress resistance: decreased hydrogen peroxide C. albicans orf19.7551 ORF ALO1 CAL0000083 PMID: 11349062|CGD_REF: CAL0080715 heterozygous diploid, classical genetics overexpression Not recorded oxidative stress resistance: increased hydrogen peroxide C. albicans orf19.7551 ORF ALO1 CAL0000083 PMID: 18282465|CGD_REF: CAL0118812 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased cyanide resumption of growth is delayed in the presence of cyanide, but no defect in log phase growth C. albicans orf19.7551 ORF ALO1 CAL0000083 PMID: 11349062|CGD_REF: CAL0080715 homozygous diploid, classical genetics null Not recorded oxidative stress resistance: decreased menadione C. albicans orf19.7551 ORF ALO1 CAL0000083 PMID: 11349062|CGD_REF: CAL0080715 heterozygous diploid, classical genetics overexpression Not recorded oxidative stress resistance: increased menadione C. albicans orf19.7551 ORF ALO1 CAL0000083 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.7551 ORF ALO1 CAL0000083 PMID: 11349062|CGD_REF: CAL0080715 heterozygous diploid, classical genetics null Not recorded viable C. albicans orf19.7551 ORF ALO1 CAL0000083 PMID: 11349062|CGD_REF: CAL0080715 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.7551 ORF ALO1 CAL0000083 PMID: 11349062|CGD_REF: CAL0080715 heterozygous diploid, classical genetics overexpression Not recorded viable C. albicans orf19.7551 ORF ALO1 CAL0000083 PMID: 11349062|CGD_REF: CAL0080715 homozygous diploid, classical genetics null Not recorded virulence: decreased mouse intravenous infection C. albicans orf19.7551 ORF ALO1 CAL0000083 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 invasive growth: decreased solid SLAD media C. albicans orf19.7552 ORF CAL0000085 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.7554 ORF CAL0000090 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.7554 ORF CAL0000090 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.7554 ORF CAL0000090 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.7554 ORF CAL0000090 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.7557 ORF FGR46 CAL0000097 PMID: 12773383|CGD_REF: CAL0087974 heterozygous diploid, classical genetics (haploinsufficient phenotype assay) unspecified CAI-4 filamentous growth: increased solid Spider medium or solid YEPD plus serum transposon insertion proximal to, but not within, the ORF C. albicans orf19.7557 ORF FGR46 CAL0000097 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 invasive growth: decreased solid SLAD media C. albicans orf19.7558 ORF YTA6 CAL0000099 PMID: 12773383|CGD_REF: CAL0087974 heterozygous diploid, classical genetics (haploinsufficient phenotype assay) unspecified CAI-4 filamentous growth: increased solid Spider medium or solid YEPD plus serum transposon insertion proximal to, but not within, the ORF C. albicans orf19.7558 ORF YTA6 CAL0000099 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.756 ORF SAP7 CAL0001866 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.756 ORF SAP7 CAL0001866 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.756 ORF SAP7 CAL0001866 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.756 ORF SAP7 CAL0001866 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.756 ORF SAP7 CAL0001866 PMID: 16177393|CGD_REF: CAL0114766 homozygous diploid, classical genetics null Not recorded virulence: decreased mouse intravenous infection C. albicans orf19.756 ORF SAP7 CAL0001866 PMID: 16177393|CGD_REF: CAL0114766 homozygous diploid, classical genetics null Not recorded virulence: normal immunosuppressed mouse short-term infection mouse pulmonary infection C. albicans orf19.756 ORF SAP7 CAL0001866 PMID: 16177393|CGD_REF: CAL0114766 homozygous diploid, classical genetics null Not recorded virulence: normal mouse vaginal infection C. albicans orf19.756 ORF SAP7 CAL0001866 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.7561 ORF DEF1 CAL0000121 PMID: 17645752|CGD_REF: CAL0119305 heterozygous diploid, classical genetics null BWP17 filamentous growth: decreased little or no filamentation under several different conditions that induce filamentous growth and agar invasion in wild type C. albicans orf19.7561 ORF DEF1 CAL0000121 PMID: 17645752|CGD_REF: CAL0119305 homozygous diploid, classical genetics null BWP17 filamentous growth: decreased little or no filamentation under several different conditions that induce filamentous growth and agar invasion in wild type C. albicans orf19.7561 ORF DEF1 CAL0000121 PMID: 19057660|CGD_REF: CAL0121272 homozygous diploid, classical genetics null Not recorded resistance to chemicals: increased caspofungin filamentous cells appear to be more sensitive than yeast-form cells C. albicans orf19.7561 ORF DEF1 CAL0000121 PMID: 21407800|CGD_REF: CAL0141800 homozygous diploid, large-scale survey null BWP17 interaction with host/environment: abnormal significantly reduced damage to epithelial cells, but normal adhesion and invasion ex vivo model of infection C. albicans orf19.7561 ORF DEF1 CAL0000121 PMID: 21512583|CGD_REF: CAL0141906 homozygous diploid, classical genetics null SC5314 filamentous growth: abnormal produces budding filaments, the budding of yeast cells from the initial filaments C. albicans orf19.7561 ORF DEF1 CAL0000121 PMID: 21512583|CGD_REF: CAL0141906 homozygous diploid, classical genetics null SC5314 hyphal growth: abnormal unable to produce true hyphae in liquid media and only transiently produced filaments during contact with oral epithelial cells, but switched to yeast cell growth during the infection process C. albicans orf19.7561 ORF DEF1 CAL0000121 PMID: 21512583|CGD_REF: CAL0141906 homozygous diploid, classical genetics null SC5314 adhesion: decreased decreased adhesion properties to plastic surfaces C. albicans orf19.7561 ORF DEF1 CAL0000121 PMID: 21512583|CGD_REF: CAL0141906 homozygous diploid, classical genetics null SC5314 RNA accumulation: decreased UME6 mRNA C. albicans orf19.7561 ORF DEF1 CAL0000121 PMID: 17645752|CGD_REF: CAL0119305 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.7561 ORF DEF1 CAL0000121 PMID: 17645752|CGD_REF: CAL0119305 homozygous diploid, classical genetics null Not recorded virulence: decreased reconstituted human epithelium decreased capacity to cause tissue damage ex vivo model of infection C. albicans orf19.7563 ORF BET2 CAL0000126 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.7563 ORF BET2 CAL0000126 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient SLAD medium C. albicans orf19.7564 ORF DPB2 CAL0000130 PMID: 10953084|CGD_REF: CAL0081154 heterozygous diploid, classical genetics repressible dpb2::hisG/dpb2::MAL2-DPB2::URA3 CAI-4 inviable C. albicans orf19.7564 ORF DPB2 CAL0000130 PMID: 10953084|CGD_REF: CAL0081154 heterozygous diploid, classical genetics null dpb2::hisG-URA3-hisG/DPB2 CAI-4 viable C. albicans orf19.7564 ORF DPB2 CAL0000130 PMID: 14507372|CGD_REF: CAL0088818 heterozygous diploid, large-scale survey (large-scale identification of essential genes by gene replacement and conditional expression (GRACE) method) repressible CAI-4 inviable one allele is deleted and the other is placed under repressible Tet promoter C. albicans orf19.7564 ORF DPB2 CAL0000130 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient YNB medium C. albicans orf19.7565 ORF GNP3 CAL0000134 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.7566 ORF CAL0000137 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.7569 ORF SIK1 CAL0000142 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.757 ORF CAL0001868 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.757 ORF CAL0001868 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.757 ORF CAL0001868 PMID: 19463063|CGD_REF: CAL0123630 homozygous diploid, systematic mutation set (split-marker transposon insertion strategy to disrupt both alleles) null BWP17 viable C. albicans orf19.757 ORF CAL0001868 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.757 ORF CAL0001868 PMID: 19463063|CGD_REF: CAL0123630 homozygous diploid, systematic mutation set (split-marker transposon insertion strategy to disrupt both alleles) null BWP17 virulence: normal Toll mutant D. melanogaster invasive infection insect infection C. albicans orf19.757 ORF CAL0001868 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.7570 ORF UGA3 CAL0000161 PMID: 20041210|CGD_REF: CAL0124764 homozygous diploid, systematic mutation set null SN152 utilization of nitrogen source: decreased GABA (40 mM gamma-aminobutyric acid) strongly decreased C. albicans orf19.7570 ORF UGA3 CAL0000161 PMID: 15964282|CGD_REF: CAL0114274 homozygous diploid, systematic mutation set (split-marker transposon insertion strategy to disrupt both alleles) null BWP17 biofilm formation: normal C. albicans orf19.7570 ORF UGA3 CAL0000161 PMID: 15964282|CGD_REF: CAL0114274 homozygous diploid, systematic mutation set (split-marker transposon insertion strategy to disrupt both alleles) null BWP17 viable C. albicans orf19.7571 ORF UBC4 CAL0000163 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.7572 ORF SPT7 CAL0000166 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, competitive growth (haploinsufficient phenotype assay, barcode deletion set) null SC5314 resistance to chemicals: decreased ergosterol analogs (ECC69 and/or ECC1384) C. albicans orf19.7572 ORF SPT7 CAL0000166 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, competitive growth (haploinsufficient phenotype assay, barcode deletion set) null SC5314 resistance to chemicals: decreased amphotericin B C. albicans orf19.7572 ORF SPT7 CAL0000166 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.7574 ORF CAL0000172 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.7574 ORF CAL0000172 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.7574 ORF CAL0000172 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.7574 ORF CAL0000172 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.7574 ORF CAL0000172 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.7576 ORF CAL0000178 PMID: 14663094|CGD_REF: CAL0080633 homozygous diploid, systematic mutation set (homozygous insertion mutants generated with URA3-ARG4-URA3 (UAU1) cassette) null BWP17 viable C. albicans orf19.7577 ORF MSS51 CAL0000180 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.7579 ORF FGR34 CAL0000184 PMID: 12773383|CGD_REF: CAL0087974 heterozygous diploid, classical genetics (haploinsufficient phenotype assay) null CAI-4 filamentous growth: increased solid Spider medium heterozygous transposon insertion C. albicans orf19.7579 ORF FGR34 CAL0000184 PMID: 12773383|CGD_REF: CAL0087974 heterozygous diploid, classical genetics (haploinsufficient phenotype assay) unspecified CAI-4 filamentous growth: increased solid Spider medium transposon insertion proximal to, but not within, the ORF C. albicans orf19.7579 ORF FGR34 CAL0000184 PMID: 12773383|CGD_REF: CAL0087974 heterozygous diploid, classical genetics (haploinsufficient phenotype assay) null CAI-4 colony size: decreased solid Spider medium heterozygous transposon insertion C. albicans orf19.7579 ORF FGR34 CAL0000184 PMID: 12773383|CGD_REF: CAL0087974 heterozygous diploid, classical genetics (haploinsufficient phenotype assay) null CAI-4 viable heterozygous transposon insertion C. albicans orf19.7581 ORF CAL0000205 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.7583 ORF ZCF39 CAL0000209 PMID: 15964282|CGD_REF: CAL0114274 homozygous diploid, systematic mutation set (split-marker transposon insertion strategy to disrupt both alleles) null BWP17 biofilm formation: normal C. albicans orf19.7583 ORF ZCF39 CAL0000209 PMID: 22073120|CGD_REF: CAL0000143592 homozygous diploid, classical genetics null BWP17 viable C. albicans orf19.7583 ORF ZCF39 CAL0000209 PMID: 22073120|CGD_REF: CAL0000143592 homozygous diploid, classical genetics null BWP17 colony appearance: abnormal increased colony wrinkling C. albicans orf19.7583 ORF ZCF39 CAL0000209 PMID: 14663094|CGD_REF: CAL0080633 homozygous diploid, systematic mutation set (homozygous insertion mutants generated with URA3-ARG4-URA3 (UAU1) cassette) null BWP17 viable C. albicans orf19.7583 ORF ZCF39 CAL0000209 PMID: 15964282|CGD_REF: CAL0114274 homozygous diploid, systematic mutation set (split-marker transposon insertion strategy to disrupt both alleles) null BWP17 viable C. albicans orf19.7583 ORF ZCF39 CAL0000209 PMID: 19463063|CGD_REF: CAL0123630 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.7583 ORF ZCF39 CAL0000209 PMID: 22359502|CGD_REF: CAL0000144048 homozygous diploid, classical genetics null BWP17 viable insertion mutant, independent BWP17 and SN152 deletion mutants also tested C. albicans orf19.7583 ORF ZCF39 CAL0000209 PMID: 22359502|CGD_REF: CAL0000144048 homozygous diploid, classical genetics null BWP17 adhesion: decreased insertion mutant, independent BWP17 and SN152 deletion mutants also tested C. albicans orf19.7583 ORF ZCF39 CAL0000209 PMID: 19463063|CGD_REF: CAL0123630 homozygous diploid, systematic mutation set (split-marker transposon insertion strategy to disrupt both alleles) null BWP17 virulence: normal Toll mutant D. melanogaster invasive infection insect infection C. albicans orf19.7585 ORF INO1 CAL0000215 PMID: 18268031|CGD_REF: CAL0118829 homozygous diploid, classical genetics null Not recorded auxotrophy inositol C. albicans orf19.7585 ORF INO1 CAL0000215 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.7585 ORF INO1 CAL0000215 PMID: 18268031|CGD_REF: CAL0118829 heterozygous diploid, classical genetics null Not recorded viable C. albicans orf19.7585 ORF INO1 CAL0000215 PMID: 18268031|CGD_REF: CAL0118829 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.7585 ORF INO1 CAL0000215 PMID: 18268031|CGD_REF: CAL0118829 heterozygous diploid, classical genetics null Not recorded virulence: normal mouse intravenous infection C. albicans orf19.7585 ORF INO1 CAL0000215 PMID: 18268031|CGD_REF: CAL0118829 homozygous diploid, classical genetics null Not recorded virulence: normal mouse intravenous infection C. albicans orf19.7585 ORF INO1 CAL0000215 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 invasive growth: decreased solid SLAD media C. albicans orf19.7586 ORF CHT3 CAL0000219 PMID: 16214381|CGD_REF: CAL0114979 homozygous diploid, classical genetics null Not recorded protein activity: decreased severely decreased cellular chitinase activity, indicating that Cht3p is the major chitinase in yeast-form cells chitinase C. albicans orf19.7586 ORF CHT3 CAL0000219 PMID: 16214381|CGD_REF: CAL0114979 homozygous diploid, classical genetics null Not recorded budding pattern: abnormal budding is unipolar C. albicans orf19.7586 ORF CHT3 CAL0000219 PMID: 16214381|CGD_REF: CAL0114979 heterozygous diploid, classical genetics repressible Not recorded cytokinesis: decreased defect in cell separation C. albicans orf19.7586 ORF CHT3 CAL0000219 PMID: 16214381|CGD_REF: CAL0114979 homozygous diploid, classical genetics null Not recorded cytokinesis: absent C. albicans orf19.7586 ORF CHT3 CAL0000219 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.7586 ORF CHT3 CAL0000219 PMID: 16214381|CGD_REF: CAL0114979 heterozygous diploid, classical genetics null Not recorded viable C. albicans orf19.7586 ORF CHT3 CAL0000219 PMID: 16214381|CGD_REF: CAL0114979 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.759 ORF SEC21 CAL0001871 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.7590 ORF CAL0000236 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: decreased growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.7590 ORF CAL0000236 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.7590 ORF CAL0000236 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: decreased rate liquid synthetic complete medium C. albicans orf19.7590 ORF CAL0000236 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.7592 ORF FAA4 CAL0000241 PMID: 21414038|CGD_REF: CAL0141808 homozygous diploid, classical genetics null BWP17 viable C. albicans orf19.7592 ORF FAA4 CAL0000241 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.7594 ORF CAL0000247 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.7596 ORF CAL0000255 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.7599 ORF UTP5 CAL0000260 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, competitive growth (haploinsufficient phenotype assay, barcode deletion set) null SC5314 resistance to chemicals: increased 5-fluorouracil C. albicans orf19.7599 ORF UTP5 CAL0000260 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, competitive growth (haploinsufficient phenotype assay, barcode deletion set) null SC5314 resistance to chemicals: increased tubercidin C. albicans orf19.7599 ORF UTP5 CAL0000260 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, competitive growth (haploinsufficient phenotype assay, barcode deletion set) null SC5314 resistance to chemicals: increased flucytosine C. albicans orf19.7599 ORF UTP5 CAL0000260 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.7599 ORF UTP5 CAL0000260 PMID: 21135205|CGD_REF: CAL0139967 heterozygous diploid, competitive growth (large-scale identification of genes essential for virulence in mouse) repressible CAI-4 virulence: decreased mouse intravenous infection C. albicans orf19.76 ORF SPB1 CAL0000659 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.7600 ORF FDH3 CAL0000792 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.7602 ORF AHA1 CAL0000794 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.7604 ORF CAL0000796 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.7605 ORF PUP1 CAL0000797 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.7605 ORF PUP1 CAL0000797 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 invasive growth: decreased solid SLAD media C. albicans orf19.7605 ORF PUP1 CAL0000797 PMID: 21135205|CGD_REF: CAL0139967 heterozygous diploid, large-scale survey (large-scale identification of genes essential for virulence in mouse) repressible CAI-4 virulence: absent mouse intravenous infection C. albicans orf19.761 ORF TCO89 CAL0001891 PMID: 17298473|CGD_REF: CAL0117873 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased lithium(1+) C. albicans orf19.761 ORF TCO89 CAL0001891 PMID: 17298473|CGD_REF: CAL0117873 homozygous diploid, classical genetics null Not recorded flocculation: increased C. albicans orf19.761 ORF TCO89 CAL0001891 PMID: 19115836|CGD_REF: CAL0122036 heterozygous diploid, competitive growth (haploinsufficient phenotype assay, barcode deletion set) null SC5314 resistance to chemicals: decreased rapamycin C. albicans orf19.761 ORF TCO89 CAL0001891 PMID: 17298473|CGD_REF: CAL0117873 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased rapamycin C. albicans orf19.761 ORF TCO89 CAL0001891 PMID: 17298473|CGD_REF: CAL0117873 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.7610 ORF PTP3 CAL0000818 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.7610 ORF PTP3 CAL0000818 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.7610 ORF PTP3 CAL0000818 PMID: 14663094|CGD_REF: CAL0080633 homozygous diploid, systematic mutation set (homozygous insertion mutants generated with URA3-ARG4-URA3 (UAU1) cassette) null BWP17 viable C. albicans orf19.7610 ORF PTP3 CAL0000818 PMID: 18708562|CGD_REF: CAL0119375 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.7610 ORF PTP3 CAL0000818 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: abnormal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.7610 ORF PTP3 CAL0000818 PMID: 23856128|CGD_REF: CAL0000172540 homozygous diploid, classical genetics null BWP17 resistance to chemicals: decreased propolis C. albicans orf19.7610 ORF PTP3 CAL0000818 PMID: 18708562|CGD_REF: CAL0119375 homozygous diploid, classical genetics null Not recorded virulence: decreased insect infection C. albicans orf19.7610 ORF PTP3 CAL0000818 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.7610 ORF PTP3 CAL0000818 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.7611 ORF TRX1 CAL0000819 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.7611 ORF TRX1 CAL0000819 PMID: 20679492|CGD_REF: CAL0126003 homozygous diploid, classical genetics null trx1::loxP-ARG4-loxP/trx1::loxP-HIS1-loxP Other C. albicans viable C. albicans orf19.7611 ORF TRX1 CAL0000819 PMID: 20679492|CGD_REF: CAL0126003 homozygous diploid, classical genetics null trx1::loxP-ARG4-loxP/trx1::loxP-HIS1-loxP Other C. albicans oxidative stress resistance: decreased hydrogen peroxide C. albicans orf19.7611 ORF TRX1 CAL0000819 PMID: 20679492|CGD_REF: CAL0126003 homozygous diploid, classical genetics null trx1::loxP-ARG4-loxP/trx1::loxP-HIS1-loxP Other C. albicans auxotrophy methionine C. albicans orf19.7611 ORF TRX1 CAL0000819 PMID: 20679492|CGD_REF: CAL0126003 homozygous diploid, classical genetics null trx1::loxP-ARG4-loxP/trx1::loxP-HIS1-loxP (similar effects of trx1-C30S and trx1-C33S alleles) Other C. albicans filamentous growth: increased non-inducing and non-stressed conditions C. albicans orf19.7611 ORF TRX1 CAL0000819 PMID: 20679492|CGD_REF: CAL0126003 homozygous diploid, classical genetics null trx1::loxP-ARG4-loxP/trx1::loxP-HIS1-loxP Other C. albicans virulence: decreased mouse intravenous infection C. albicans orf19.7614 ORF CAL0000822 PMID: 14663094|CGD_REF: CAL0080633 homozygous diploid, systematic mutation set (homozygous insertion mutants generated with URA3-ARG4-URA3 (UAU1) cassette) null BWP17 viable C. albicans orf19.7614 ORF CAL0000822 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 invasive growth: decreased solid SLAD media C. albicans orf19.7615 ORF CAL0000823 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.7615 ORF CAL0000823 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient YPD medium C. albicans orf19.7615 ORF CAL0000823 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient SC medium C. albicans orf19.7615 ORF CAL0000823 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient YNB medium C. albicans orf19.7617 ORF CAL0000824 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.7617 ORF CAL0000824 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 invasive growth: decreased solid SLAD media C. albicans orf19.7618 ORF CAL0000825 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.7619 ORF CAL0000826 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.762 ORF CAL0001893 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.762 ORF CAL0001893 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: abnormal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.762 ORF CAL0001893 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.762 ORF CAL0001893 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.762 ORF CAL0001893 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.7620 ORF CAL0000845 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.7622 ORF SPT3 CAL0000847 PMID: 12072450|CGD_REF: CAL0081308 homozygous diploid, classical genetics null BWP17 filamentous growth: increased hyperfilamentation (hyphae and pseudohyphae) under both inducing and noninducing conditions C. albicans orf19.7622 ORF SPT3 CAL0000847 PMID: 12072450|CGD_REF: CAL0081308 homozygous diploid, classical genetics null Not recorded flocculation: increased C. albicans orf19.7622 ORF SPT3 CAL0000847 PMID: 12072450|CGD_REF: CAL0081308 homozygous diploid, classical genetics null Not recorded vegetative growth: decreased rate both solid and liquid media C. albicans orf19.7622 ORF SPT3 CAL0000847 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.7622 ORF SPT3 CAL0000847 PMID: 12072450|CGD_REF: CAL0081308 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.7622 ORF SPT3 CAL0000847 PMID: 12072450|CGD_REF: CAL0081308 homozygous diploid, classical genetics null Not recorded virulence: absent mouse intravenous infection C. albicans orf19.7624 ORF CAL0000848 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.7625 ORF PGA1 CAL0000849 PMID: 20406396|CGD_REF: CAL0125395 homozygous diploid, classical genetics null RM1000 resistance to chemicals: decreased Calcofluor White (100 micrograms/ml) C. albicans orf19.7625 ORF PGA1 CAL0000849 PMID: 20406396|CGD_REF: CAL0125395 homozygous diploid, classical genetics null RM1000 viable C. albicans orf19.7625 ORF PGA1 CAL0000849 PMID: 20406396|CGD_REF: CAL0125395 homozygous diploid, classical genetics null RM1000 resistance to chemicals: decreased Congo Red (50 micrograms/ml) C. albicans orf19.7625 ORF PGA1 CAL0000849 PMID: 20406396|CGD_REF: CAL0125395 homozygous diploid, classical genetics null RM1000 resistance to chemicals: increased sodium dodecyl sulfate (0.03%) C. albicans orf19.7625 ORF PGA1 CAL0000849 PMID: 20406396|CGD_REF: CAL0125395 homozygous diploid, classical genetics null RM1000 filamentous growth: increased potato dextrose liquid and solid medium, 30 degrees C C. albicans orf19.7625 ORF PGA1 CAL0000849 PMID: 20406396|CGD_REF: CAL0125395 heterozygous diploid, classical genetics null RM1000 biofilm formation: decreased decreased adhesion to polystyrene microtitre plates C. albicans orf19.7625 ORF PGA1 CAL0000849 PMID: 20406396|CGD_REF: CAL0125395 heterozygous diploid, classical genetics null RM1000 chitin deposition: decreased chitin levels are intermediate between wild-type and the homozygous null mutant C. albicans orf19.7625 ORF PGA1 CAL0000849 PMID: 20406396|CGD_REF: CAL0125395 homozygous diploid, classical genetics null RM1000 chitin deposition: decreased C. albicans orf19.7625 ORF PGA1 CAL0000849 PMID: 20406396|CGD_REF: CAL0125395 homozygous diploid, classical genetics null RM1000 adhesion: decreased human epithelial cell line Ht-29 adhesion to human epithelial cells decreased by 50% compared to wild-type C. albicans orf19.7625 ORF PGA1 CAL0000849 PMID: 20406396|CGD_REF: CAL0125395 heterozygous diploid, classical genetics null RM1000 adhesion: decreased human epithelial cell line Ht-29 level of adhesion is intermediate between wild-type and the homozygous null mutant C. albicans orf19.7625 ORF PGA1 CAL0000849 PMID: 20406396|CGD_REF: CAL0125395 homozygous diploid, classical genetics null RM1000 biofilm formation: decreased decreased adhesion to polystyrene microtitre plates C. albicans orf19.7626 ORF EIF4E CAL0000850 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.7626 ORF EIF4E CAL0000850 PMID: 16212935|CGD_REF: CAL0114868 heterozygous diploid, classical genetics overexpression Not recorded viable no apparent phenotype C. albicans orf19.7627 ORF CAL0000851 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.7627 ORF CAL0000851 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 invasive growth: decreased solid SLAD media C. albicans orf19.7629 ORF CAL0000852 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.7629 ORF CAL0000852 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient YPD medium C. albicans orf19.7629 ORF CAL0000852 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient SC medium C. albicans orf19.763 ORF CAL0001895 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.7631 ORF SLD5 CAL0000861 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.7634 ORF MCD1 CAL0000863 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.7634 ORF MCD1 CAL0000863 PMID: 21135205|CGD_REF: CAL0139967 heterozygous diploid, large-scale survey (large-scale identification of genes essential for virulence in mouse) repressible CAI-4 virulence: absent mouse intravenous infection C. albicans orf19.7635 ORF DRS1 CAL0000864 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, competitive growth (haploinsufficient phenotype assay, barcode deletion set) null SC5314 resistance to chemicals: decreased 5-fluorouracil C. albicans orf19.7635 ORF DRS1 CAL0000864 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, competitive growth (haploinsufficient phenotype assay, barcode deletion set) null SC5314 resistance to chemicals: decreased tubercidin C. albicans orf19.7635 ORF DRS1 CAL0000864 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.7637 ORF YHB4 CAL0000865 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.7638 ORF PRO1 CAL0000866 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.764 ORF CAL0001899 PMID: 21135205|CGD_REF: CAL0139967 heterozygous diploid, competitive growth (large-scale identification of genes essential for virulence in mouse) repressible CAI-4 virulence: normal mouse intravenous infection C. albicans orf19.764 ORF CAL0001899 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.764 ORF CAL0001899 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.764 ORF CAL0001899 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.764 ORF CAL0001899 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.764 ORF CAL0001899 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.764 ORF CAL0001899 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 invasive growth: decreased solid SLAD media C. albicans orf19.7644 ORF CAL0000884 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.7644 ORF CAL0000884 PMID: 21135205|CGD_REF: CAL0139967 heterozygous diploid, competitive growth (large-scale identification of genes essential for virulence in mouse) repressible CAI-4 virulence: decreased mouse intravenous infection C. albicans orf19.7645 ORF CAL0000887 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.7648 ORF CAL0000890 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.7650 ORF LTV1 CAL0000910 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.7652 ORF CKA1 CAL0000912 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.7652 ORF CKA1 CAL0000912 PMID: 15813744|CGD_REF: CAL0104042 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.7654 ORF CPR6 CAL0000916 PMID: 19115836|CGD_REF: CAL0122036 heterozygous diploid, competitive growth (haploinsufficient phenotype assay, barcode deletion set) null SC5314 resistance to chemicals: decreased virgineone C. albicans orf19.7654 ORF CPR6 CAL0000916 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.7655 ORF RPO21 CAL0000919 PMID: 12773383|CGD_REF: CAL0087974 heterozygous diploid, classical genetics (haploinsufficient phenotype assay) null CAI-4 filamentous growth: decreased solid Spider medium heterozygous transposon insertion C. albicans orf19.7655 ORF RPO21 CAL0000919 PMID: 12773383|CGD_REF: CAL0087974 heterozygous diploid, classical genetics (haploinsufficient phenotype assay) null CAI-4 viable heterozygous transposon insertion C. albicans orf19.7655 ORF RPO21 CAL0000919 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.7657 ORF POP3 CAL0000921 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.7658 ORF RFC4 CAL0000922 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.7660 ORF VPS52 CAL0000940 PMID: 20141603|CGD_REF: CAL0124951 homozygous diploid, classical genetics null SN95 hyphal growth: absent liquid YPD plus 10% serum at 37 deg C pseudohyphal growth occurs under hyphal-inducing conditions C. albicans orf19.7660 ORF VPS52 CAL0000940 PMID: 20141603|CGD_REF: CAL0124951 heterozygous diploid, classical genetics null SN95 hyphal growth: normal liquid YPD plus 10% serum at 37 deg C C. albicans orf19.7660 ORF VPS52 CAL0000940 PMID: 20141603|CGD_REF: CAL0124951 homozygous diploid, systematic mutation set (homozygous insertion mutants generated with URA3-ARG4-URA3 (UAU1) cassette) null BWP17 hyphal growth: absent YPD plus 10% serum at 37 deg C C. albicans orf19.7660 ORF VPS52 CAL0000940 PMID: 20141603|CGD_REF: CAL0124951 homozygous diploid, systematic mutation set (homozygous insertion mutants generated with URA3-ARG4-URA3 (UAU1) cassette) null BWP17 colony appearance: abnormal 10% serum or Spider media at 37 deg C colonies are smooth C. albicans orf19.7660 ORF VPS52 CAL0000940 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.7660 ORF VPS52 CAL0000940 PMID: 20141603|CGD_REF: CAL0124951 homozygous diploid, systematic mutation set (homozygous insertion mutants generated with URA3-ARG4-URA3 (UAU1) cassette) null BWP17 viable C. albicans orf19.7660 ORF VPS52 CAL0000940 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 invasive growth: decreased solid SLAD media C. albicans orf19.7661 ORF HMI1 CAL0000942 PMID: 17311590|CGD_REF: CAL0117313 homozygous diploid, classical genetics null Not recorded mitochondrial distribution: abnormal C. albicans orf19.7661 ORF HMI1 CAL0000942 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.7661 ORF HMI1 CAL0000942 PMID: 17311590|CGD_REF: CAL0117313 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.7662 ORF CAL0000943 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 invasive growth: decreased solid SLAD media C. albicans orf19.7666 ORF CAL0000952 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.7667 ORF IAH1 CAL0000954 PMID: 12773383|CGD_REF: CAL0087974 heterozygous diploid, classical genetics (haploinsufficient phenotype assay) unspecified CAI-4 filamentous growth: increased solid Spider medium or solid YEPD plus serum transposon insertion proximal to, but not within, the ORF C. albicans orf19.7667 ORF IAH1 CAL0000954 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, competitive growth (haploinsufficient phenotype assay, barcode deletion set) null SC5314 resistance to chemicals: decreased tunicamycin C. albicans orf19.7667 ORF IAH1 CAL0000954 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.7668 ORF MAL2 CAL0000956 PMID: 12773383|CGD_REF: CAL0087974 heterozygous diploid, classical genetics (haploinsufficient phenotype assay) null CAI-4 filamentous growth: increased solid YEPD plus serum heterozygous transposon insertion C. albicans orf19.7668 ORF MAL2 CAL0000956 PMID: 12773383|CGD_REF: CAL0087974 heterozygous diploid, classical genetics (haploinsufficient phenotype assay) unspecified CAI-4 filamentous growth: increased solid Spider medium or solid YEPD plus serum transposon insertion proximal to, but not within, the ORF C. albicans orf19.7668 ORF MAL2 CAL0000956 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.7668 ORF MAL2 CAL0000956 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.7668 ORF MAL2 CAL0000956 PMID: 12773383|CGD_REF: CAL0087974 heterozygous diploid, classical genetics (haploinsufficient phenotype assay) null CAI-4 viable heterozygous transposon insertion C. albicans orf19.7668 ORF MAL2 CAL0000956 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.7668 ORF MAL2 CAL0000956 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.7668 ORF MAL2 CAL0000956 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.767 ORF ERG3 CAL0001905 PMID: 16436713|CGD_REF: CAL0115445 homozygous diploid, classical genetics null CAI-4 filamentous growth: absent various media C. albicans orf19.767 ORF ERG3 CAL0001905 PMID: 16436713|CGD_REF: CAL0115445 heterozygous diploid, classical genetics null CAI-4 filamentous growth: normal C. albicans orf19.767 ORF ERG3 CAL0001905 PMID: 16127034|CGD_REF: CAL0114593 homozygous diploid, classical genetics null Other C. albicans hyphal growth: decreased serum-containing medium at 37 deg C C. albicans orf19.767 ORF ERG3 CAL0001905 PMID: 16436713|CGD_REF: CAL0115445 homozygous diploid, classical genetics null CAI-4 hyphal growth: decreased on various media or in mouse kidney C. albicans orf19.767 ORF ERG3 CAL0001905 PMID: 16127034|CGD_REF: CAL0114593 homozygous diploid, classical genetics null Not recorded resistance to chemicals: increased amphotericin B slight increase C. albicans orf19.767 ORF ERG3 CAL0001905 PMID: 10433965|CGD_REF: CAL0081260 heterozygous diploid, classical genetics unspecified Other C. albicans resistance to chemicals: increased triazoles Darlington strain C. albicans orf19.767 ORF ERG3 CAL0001905 PMID: 16127034|CGD_REF: CAL0114593 homozygous diploid, classical genetics null Not recorded resistance to chemicals: increased triazoles C. albicans orf19.767 ORF ERG3 CAL0001905 PMID: 21135205|CGD_REF: CAL0139967 heterozygous diploid, competitive growth (large-scale identification of genes essential for virulence in mouse) repressible CAI-4 virulence: normal mouse intravenous infection C. albicans orf19.767 ORF ERG3 CAL0001905 PMID: 8980781|CGD_REF: CAL0081259 unknown ploidy, classical genetics unspecified Other C. albicans resistance to chemicals: increased amphotericin B|fluconazole C. albicans orf19.767 ORF ERG3 CAL0001905 PMID: 8980781|CGD_REF: CAL0081259 unknown ploidy, classical genetics unspecified Other C. albicans chemical compound accumulation: abnormal sterol C. albicans orf19.767 ORF ERG3 CAL0001905 PMID: 15473366|CGD_REF: CAL0082468 unknown ploidy, classical genetics unspecified CAI-8 viable homozygosis induced by growth at 37 degrees C with heat shock at 53 degrees C C. albicans orf19.767 ORF ERG3 CAL0001905 PMID: 8980781|CGD_REF: CAL0081259 unknown ploidy, classical genetics unspecified Other C. albicans viable C. albicans orf19.767 ORF ERG3 CAL0001905 PMID: 16436713|CGD_REF: CAL0115445 homozygous diploid, classical genetics null CAI-4 viable C. albicans orf19.767 ORF ERG3 CAL0001905 PMID: 16436713|CGD_REF: CAL0115445 homozygous diploid, classical genetics null CAI-4 chemical compound accumulation: abnormal sterol chebi_ontology|ergosterol is replaced by ergosta-7,22-dien-3beta-ol, and C5,6-desaturated sterols are absent C. albicans orf19.767 ORF ERG3 CAL0001905 PMID: 16436713|CGD_REF: CAL0115445 homozygous diploid, classical genetics null CAI-4 virulence: decreased exhibits decreased kidney colonization and decreased filamentation in kidney mouse intravenous infection C. albicans orf19.767 ORF ERG3 CAL0001905 PMID: 12878497|CGD_REF: CAL0081252 homozygous diploid, classical genetics null CAF2-1 resistance to chemicals: decreased amphotericin B slight decrease C. albicans orf19.767 ORF ERG3 CAL0001905 PMID: 12878497|CGD_REF: CAL0081252 homozygous diploid, classical genetics null Other C. albicans resistance to chemicals: increased fluconazole C. albicans orf19.767 ORF ERG3 CAL0001905 PMID: 16127034|CGD_REF: CAL0114593 heterozygous diploid, classical genetics null Other C. albicans chemical compound accumulation: normal triazoles C. albicans orf19.767 ORF ERG3 CAL0001905 PMID: 12878497|CGD_REF: CAL0081252 homozygous diploid, classical genetics null Other C. albicans resistance to chemicals: decreased brefeldin A C. albicans orf19.767 ORF ERG3 CAL0001905 PMID: 12878497|CGD_REF: CAL0081252 homozygous diploid, classical genetics null CAF2-1 viable C. albicans orf19.767 ORF ERG3 CAL0001905 PMID: 12878497|CGD_REF: CAL0081252 homozygous diploid, classical genetics null CAF2-1 resistance to chemicals: decreased cycloheximide C. albicans orf19.767 ORF ERG3 CAL0001905 PMID: 12878497|CGD_REF: CAL0081252 homozygous diploid, classical genetics null CAF2-1 resistance to chemicals: decreased fluphenazine C. albicans orf19.767 ORF ERG3 CAL0001905 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.767 ORF ERG3 CAL0001905 PMID: 10433965|CGD_REF: CAL0081260 heterozygous diploid, classical genetics unspecified Other C. albicans viable Darlington strain C. albicans orf19.767 ORF ERG3 CAL0001905 PMID: 19089303|CGD_REF: CAL0122011 homozygous diploid, classical genetics unspecified Not recorded viable strain with laboratory-evolved fluconazole resistance is found to have acquired ERG3-D19E and TAC1-L47K, N977K changes; causality was not demonstrated between these mutations and the drug resistance phenotype C. albicans orf19.767 ORF ERG3 CAL0001905 PMID: 16127034|CGD_REF: CAL0114593 heterozygous diploid, classical genetics null Not recorded viable C. albicans orf19.767 ORF ERG3 CAL0001905 PMID: 16127034|CGD_REF: CAL0114593 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.767 ORF ERG3 CAL0001905 PMID: 16127034|CGD_REF: CAL0114593 homozygous diploid, classical genetics null Not recorded virulence: decreased exhibits normal kidney colonization mouse intravenous infection C. albicans orf19.7670 ORF CAL0000974 PMID: 22438810|CGD_REF: CAL0000156986 homozygous diploid, classical genetics null BWP17 viable C. albicans orf19.7670 ORF CAL0000974 PMID: 22438810|CGD_REF: CAL0000156986 homozygous diploid, classical genetics null BWP17 virulence: decreased mutants have reduced capacity to damage oral epithelial cells in vitro model of infection (monolayers of oral epithelial cells) C. albicans orf19.7673 ORF CAL0000979 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.7676 ORF XYL2 CAL0000985 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.7678 ORF ATP16 CAL0000987 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.768 ORF SYG1 CAL0001907 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.768 ORF SYG1 CAL0001907 PMID: 14663094|CGD_REF: CAL0080633 homozygous diploid, systematic mutation set (homozygous insertion mutants generated with URA3-ARG4-URA3 (UAU1) cassette) null BWP17 viable C. albicans orf19.769 ORF IFE1 CAL0001909 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.769 ORF IFE1 CAL0001909 PMID: 14663094|CGD_REF: CAL0080633 homozygous diploid, systematic mutation set (homozygous insertion mutants generated with URA3-ARG4-URA3 (UAU1) cassette) null BWP17 viable C. albicans orf19.771 ORF LPG20 CAL0001933 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.771 ORF LPG20 CAL0001933 PMID: 14663094|CGD_REF: CAL0080633 homozygous diploid, systematic mutation set (homozygous insertion mutants generated with URA3-ARG4-URA3 (UAU1) cassette) null BWP17 viable C. albicans orf19.771 ORF LPG20 CAL0001933 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 invasive growth: decreased solid SLAD media C. albicans orf19.772 ORF LYS21 CAL0001935 PMID: 20571912|CGD_REF: CAL0125848 homozygous diploid, classical genetics null SC5314 viable C. albicans orf19.772 ORF LYS21 CAL0001935 PMID: 20571912|CGD_REF: CAL0125848 homozygous diploid, classical genetics null SC5314 virulence: normal C. albicans orf19.773 ORF CAL0001939 PMID: 23572557|CGD_REF: CAL0000158900 homozygous diploid, classical genetics null orf19.773::Tn7-UAU1/orf19.773::Tn7-URA3 BWP17 viable C. albicans orf19.778 ORF PIL1 CAL0001950 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.779 ORF HAT1 CAL0001952 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.779 ORF HAT1 CAL0001952 PMID: 23075292|CGD_REF: CAL0000158032 homozygous diploid, classical genetics null SC5314 viable C. albicans orf19.779 ORF HAT1 CAL0001952 PMID: 23075292|CGD_REF: CAL0000158032 homozygous diploid, classical genetics null SC5314 pseudohyphal growth: increased C. albicans orf19.779 ORF HAT1 CAL0001952 PMID: 23075292|CGD_REF: CAL0000158032 homozygous diploid, classical genetics null SC5314 resistance to chemicals: decreased methyl methanesulfonate C. albicans orf19.779 ORF HAT1 CAL0001952 PMID: 23075292|CGD_REF: CAL0000158032 homozygous diploid, classical genetics null SC5314 resistance to chemicals: decreased ethanesulfonate C. albicans orf19.779 ORF HAT1 CAL0001952 PMID: 23075292|CGD_REF: CAL0000158032 homozygous diploid, classical genetics null SC5314 resistance to chemicals: decreased 4-nitroquinoline N-oxide C. albicans orf19.779 ORF HAT1 CAL0001952 PMID: 23075292|CGD_REF: CAL0000158032 homozygous diploid, classical genetics null SC5314 UV resistance: decreased C. albicans orf19.779 ORF HAT1 CAL0001952 PMID: 23075292|CGD_REF: CAL0000158032 homozygous diploid, classical genetics null SC5314 resistance to chemicals: decreased caspofungin C. albicans orf19.779 ORF HAT1 CAL0001952 PMID: 23075292|CGD_REF: CAL0000158032 homozygous diploid, classical genetics null SC5314 phenotypic switching: increased C. albicans orf19.780 ORF DUR1,2 CAL0001974 PMID: 19188358|CGD_REF: CAL0122313 homozygous diploid, classical genetics null Not recorded germ tube formation: absent arginine- or urea-containing media C. albicans orf19.780 ORF DUR1,2 CAL0001974 PMID: 19188358|CGD_REF: CAL0122313 homozygous diploid, classical genetics null Not recorded germ tube formation: absent within macrophages C. albicans orf19.780 ORF DUR1,2 CAL0001974 PMID: 19188358|CGD_REF: CAL0122313 homozygous diploid, classical genetics null Not recorded utilization of nitrogen source: absent urea C. albicans orf19.780 ORF DUR1,2 CAL0001974 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.780 ORF DUR1,2 CAL0001974 PMID: 19188358|CGD_REF: CAL0122313 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.781 ORF DUR3 CAL0001976 PMID: 22033918|CGD_REF: CAL0000143535 homozygous diploid, classical genetics null CAF2-1 toxin resistance: decreased human salivary histatin 5 C. albicans orf19.781 ORF DUR3 CAL0001976 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.781 ORF DUR3 CAL0001976 PMID: 20884691|CGD_REF: CAL0126475 homozygous diploid, classical genetics null SC5314 viable C. albicans orf19.781 ORF DUR3 CAL0001976 PMID: 20884691|CGD_REF: CAL0126475 homozygous diploid, classical genetics null SC5314 small molecule transport: decreased urea C. albicans orf19.782 ORF CAL0001978 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.782 ORF CAL0001978 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.782 ORF CAL0001978 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.782 ORF CAL0001978 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.782 ORF CAL0001978 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.783 ORF CAL0001981 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: increased growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.783 ORF CAL0001981 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: abnormal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.783 ORF CAL0001981 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, classical genetics null SN152 germ tube formation: decreased serum-containing medium C. albicans orf19.783 ORF CAL0001981 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.783 ORF CAL0001981 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.789 ORF PYC2 CAL0001995 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.791 ORF RIM11 CAL0002017 PMID: 14663094|CGD_REF: CAL0080633 homozygous diploid, systematic mutation set (homozygous insertion mutants generated with URA3-ARG4-URA3 (UAU1) cassette) null BWP17 viable C. albicans orf19.791 ORF RIM11 CAL0002017 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient YPD medium C. albicans orf19.792 ORF CAL0002019 PMID: 14663094|CGD_REF: CAL0080633 homozygous diploid, systematic mutation set (homozygous insertion mutants generated with URA3-ARG4-URA3 (UAU1) cassette) null BWP17 viable C. albicans orf19.793 ORF CAK1 CAL0002021 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.794 ORF SSN3 CAL0002024 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.794 ORF SSN3 CAL0002024 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.794 ORF SSN3 CAL0002024 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: abnormal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.794 ORF SSN3 CAL0002024 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.794 ORF SSN3 CAL0002024 PMID: 20140194|CGD_REF: CAL0124995 homozygous diploid, classical genetics null Other C. albicans oxidative stress resistance: decreased hydrogen peroxide C. albicans orf19.794 ORF SSN3 CAL0002024 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.795 ORF VPS36 CAL0002025 PMID: 18974864|CGD_REF: CAL0120463 homozygous diploid, classical genetics null Not recorded vacuolar transport: decreased defect in multivesicular body (MVB) transport to the vacuole C. albicans orf19.795 ORF VPS36 CAL0002025 PMID: 15371534|CGD_REF: CAL0082134 homozygous diploid, classical genetics null BWP17 hyphal growth: absent solid medium, alkaline pH C. albicans orf19.795 ORF VPS36 CAL0002025 PMID: 18974864|CGD_REF: CAL0120463 homozygous diploid, classical genetics null Not recorded endocytosis: decreased defect in uptake of low concentrations of histatin-5 antimicrobial salivary peptide into the vacuole C. albicans orf19.795 ORF VPS36 CAL0002025 PMID: 18466294|CGD_REF: CAL0119004 homozygous diploid, classical genetics null Not recorded utilization of iron source: absent hemoglobin C. albicans orf19.795 ORF VPS36 CAL0002025 PMID: 22427429|CGD_REF: CAL0000156990 homozygous diploid, classical genetics null BWP17 protein/peptide modification: absent mutants don't process RIM8-HA RIM8-HA C. albicans orf19.795 ORF VPS36 CAL0002025 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.795 ORF VPS36 CAL0002025 PMID: 15371534|CGD_REF: CAL0082134 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.795 ORF VPS36 CAL0002025 PMID: 22427429|CGD_REF: CAL0000156990 homozygous diploid, classical genetics null vps36::ARG4/vps36::URA3- dpl200 RIM8-HA::HIS1/RIM8 BWP17 protein/peptide modification: absent at pH 8, Rim8-HA modification was not modified to the 95-105 kD forms in this mutant Rim8-HA C. albicans orf19.795 ORF VPS36 CAL0002025 PMID: 22427429|CGD_REF: CAL0000156990 homozygous diploid, classical genetics null BWP17 protein/peptide modification: absent Rim8-HA was not modified to the 95-105 kD forms in this mutant at pH 8 Rim8-HA C. albicans orf19.795 ORF VPS36 CAL0002025 PMID: 22427429|CGD_REF: CAL0000156990 homozygous diploid, classical genetics null BWP17 protein/peptide modification: abnormal defective for RIM8-HA-processing RIM8-HA C. albicans orf19.795 ORF VPS36 CAL0002025 PMID: 20581294|CGD_REF: CAL0125802 homozygous diploid, classical genetics null BWP17 alkaline pH resistance: decreased YPD pH 9, 2 days at 37 degrees C C. albicans orf19.795 ORF VPS36 CAL0002025 PMID: 20581294|CGD_REF: CAL0125802 homozygous diploid, classical genetics null BWP17 protein/peptide modification: absent Rim101p C. albicans orf19.795 ORF VPS36 CAL0002025 PMID: 20581294|CGD_REF: CAL0125802 homozygous diploid, classical genetics null BWP17 hyphal growth: absent M199 pH 8 plates, 37 degrees C, 6 days no peripheral hyphae produced C. albicans orf19.795 ORF VPS36 CAL0002025 PMID: 20581294|CGD_REF: CAL0125802 homozygous diploid, classical genetics null BWP17 metal resistance: decreased lithium chloride (150 mM) YPD plus 150 mM lithium chloride C. albicans orf19.795 ORF VPS36 CAL0002025 PMID: 20581294|CGD_REF: CAL0125802 homozygous diploid, classical genetics null BWP17 resistance to chemicals: decreased iron chelators YPD plus 150 micromolar bathophenanthrolinedisulfonic acid (BPS) C. albicans orf19.796 ORF HYM1 CAL0002027 PMID: 18843050|CGD_REF: CAL0120345 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased fluconazole C. albicans orf19.796 ORF HYM1 CAL0002027 PMID: 18843050|CGD_REF: CAL0120345 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased Hygromycin B C. albicans orf19.796 ORF HYM1 CAL0002027 PMID: 18843050|CGD_REF: CAL0120345 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased Calcofluor White C. albicans orf19.796 ORF HYM1 CAL0002027 PMID: 18843050|CGD_REF: CAL0120345 heterozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased itraconazole sensitivity is intermediate between that of the homozygous null mutant and wild type C. albicans orf19.796 ORF HYM1 CAL0002027 PMID: 18843050|CGD_REF: CAL0120345 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased itraconazole C. albicans orf19.796 ORF HYM1 CAL0002027 PMID: 18843050|CGD_REF: CAL0120345 homozygous diploid, classical genetics null Not recorded vegetative growth: decreased rate C. albicans orf19.796 ORF HYM1 CAL0002027 PMID: 18843050|CGD_REF: CAL0120345 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased sodium dodecyl sulfate C. albicans orf19.796 ORF HYM1 CAL0002027 PMID: 18843050|CGD_REF: CAL0120345 homozygous diploid, classical genetics null Not recorded cell cycle progression: abnormal cells are multinucleate C. albicans orf19.796 ORF HYM1 CAL0002027 PMID: 18843050|CGD_REF: CAL0120345 homozygous diploid, classical genetics null CAI-4 hyphal growth: decreased solid and liquid media C. albicans orf19.796 ORF HYM1 CAL0002027 PMID: 18843050|CGD_REF: CAL0120345 homozygous diploid, classical genetics null Not recorded hypoosmotic stress resistance: decreased cells lyse in liquid YPD C. albicans orf19.796 ORF HYM1 CAL0002027 PMID: 18843050|CGD_REF: CAL0120345 homozygous diploid, classical genetics null Not recorded cell shape: abnormal cells are round and enlarged C. albicans orf19.796 ORF HYM1 CAL0002027 PMID: 18843050|CGD_REF: CAL0120345 homozygous diploid, classical genetics null Not recorded cell size: increased cells are round, large, and heterogeneous in size C. albicans orf19.796 ORF HYM1 CAL0002027 PMID: 18843050|CGD_REF: CAL0120345 homozygous diploid, classical genetics null Not recorded cytokinesis: absent C. albicans orf19.796 ORF HYM1 CAL0002027 PMID: 18843050|CGD_REF: CAL0120345 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased Congo Red C. albicans orf19.796 ORF HYM1 CAL0002027 PMID: 18843050|CGD_REF: CAL0120345 heterozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased fluconazole sensitivity is intermediate between that of the homozygous null mutant and wild type C. albicans orf19.796 ORF HYM1 CAL0002027 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.796 ORF HYM1 CAL0002027 PMID: 18843050|CGD_REF: CAL0120345 heterozygous diploid, classical genetics null Not recorded viable URA3-blaster technique C. albicans orf19.796 ORF HYM1 CAL0002027 PMID: 18843050|CGD_REF: CAL0120345 homozygous diploid, classical genetics null Not recorded viable URA3-blaster technique C. albicans orf19.797 ORF BAT21 CAL0002029 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.798 ORF TAF14 CAL0002032 PMID: 15964282|CGD_REF: CAL0114274 homozygous diploid, systematic mutation set (split-marker transposon insertion strategy to disrupt both alleles) null BWP17 biofilm formation: normal C. albicans orf19.798 ORF TAF14 CAL0002032 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.798 ORF TAF14 CAL0002032 PMID: 15964282|CGD_REF: CAL0114274 homozygous diploid, systematic mutation set (split-marker transposon insertion strategy to disrupt both alleles) null BWP17 viable C. albicans orf19.798 ORF TAF14 CAL0002032 PMID: 22359502|CGD_REF: CAL0000144048 homozygous diploid, classical genetics null BWP17 viable no independent insertion mutants; possible pleiotropic effects in this mutant C. albicans orf19.798 ORF TAF14 CAL0002032 PMID: 22359502|CGD_REF: CAL0000144048 homozygous diploid, classical genetics null BWP17 adhesion: decreased no independent insertion mutants; possible pleiotropic effects in this mutant C. albicans orf19.798 ORF TAF14 CAL0002032 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient SC medium C. albicans orf19.799 ORF STE4 CAL0002035 PMID: 18162580|CGD_REF: CAL0118948 homozygous diploid, classical genetics null Not recorded phenotypic switching: normal C. albicans orf19.799 ORF STE4 CAL0002035 PMID: 18658257|CGD_REF: CAL0119356 homozygous diploid, classical genetics null Not recorded pheromone sensitivity: decreased alpha factor mating projection not formed C. albicans orf19.799 ORF STE4 CAL0002035 PMID: 18162580|CGD_REF: CAL0118948 homozygous diploid, classical genetics null Not recorded pheromone sensitivity: decreased alpha factor reduced aggregation of white-phase cells C. albicans orf19.799 ORF STE4 CAL0002035 PMID: 18658257|CGD_REF: CAL0119356 heterozygous diploid, classical genetics overexpression Not recorded pheromone-induced cell cycle arrest: normal C. albicans orf19.799 ORF STE4 CAL0002035 PMID: 18658257|CGD_REF: CAL0119356 heterozygous diploid, classical genetics null Not recorded viable C. albicans orf19.799 ORF STE4 CAL0002035 PMID: 18658257|CGD_REF: CAL0119356 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.799 ORF STE4 CAL0002035 PMID: 18658257|CGD_REF: CAL0119356 heterozygous diploid, classical genetics overexpression Not recorded viable C. albicans orf19.799 ORF STE4 CAL0002035 PMID: 18162580|CGD_REF: CAL0118948 homozygous diploid, classical genetics null P37005 biofilm formation: decreased white cells form a biofilm of reduced thickness in the presence of opaque cells of the opposite mating type C. albicans orf19.799 ORF STE4 CAL0002035 PMID: 20494978|CGD_REF: CAL0125636 heterozygous diploid, classical genetics null BWP17 resistance to chemicals: decreased clotrimazole (75 uM) growth in liquid culture confirmation of mutant phenotypes for heterozygous transposon insertion strains showing sensitivity in a large-scale assay C. albicans orf19.799 ORF STE4 CAL0002035 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 invasive growth: decreased solid SLAD media C. albicans orf19.801 ORF TBF1 CAL0002606 PMID: 18342603|CGD_REF: CAL0118928 heterozygous diploid, classical genetics repressible Not recorded inviable heterozygous null/tet-repressible strain is inviable in the presence of tetracycline C. albicans orf19.801 ORF TBF1 CAL0002606 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.801 ORF TBF1 CAL0002606 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient SLAD medium C. albicans orf19.801 ORF TBF1 CAL0002606 PMID: 21135205|CGD_REF: CAL0139967 heterozygous diploid, large-scale survey (large-scale identification of genes essential for virulence in mouse) repressible CAI-4 virulence: absent mouse intravenous infection C. albicans orf19.804 ORF CAL0002609 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 invasive growth: decreased solid SLAD media C. albicans orf19.805 ORF CAL0002610 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.806 ORF VMA7 CAL0002611 PMID: 15870472|CGD_REF: CAL0082691 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased cobalt(2+) C. albicans orf19.806 ORF VMA7 CAL0002611 PMID: 15870472|CGD_REF: CAL0082691 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased nickel(2+) C. albicans orf19.806 ORF VMA7 CAL0002611 PMID: 15870472|CGD_REF: CAL0082691 homozygous diploid, classical genetics null Not recorded vacuolar transport: abnormal decreased vacuolar acidification C. albicans orf19.806 ORF VMA7 CAL0002611 PMID: 15870472|CGD_REF: CAL0082691 homozygous diploid, classical genetics null Not recorded alkaline pH resistance: decreased C. albicans orf19.806 ORF VMA7 CAL0002611 PMID: 15870472|CGD_REF: CAL0082691 homozygous diploid, classical genetics null BWP17 hyphal growth: absent liquid serum-containing or Spider media C. albicans orf19.806 ORF VMA7 CAL0002611 PMID: 15870472|CGD_REF: CAL0082691 homozygous diploid, classical genetics null BWP17 hyphal growth: normal solid Spider medium C. albicans orf19.806 ORF VMA7 CAL0002611 PMID: 15870472|CGD_REF: CAL0082691 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased manganese(2+) C. albicans orf19.806 ORF VMA7 CAL0002611 PMID: 15870472|CGD_REF: CAL0082691 homozygous diploid, classical genetics null Not recorded metal resistance: decreased copper(2+) C. albicans orf19.806 ORF VMA7 CAL0002611 PMID: 15870472|CGD_REF: CAL0082691 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased zinc(2+) C. albicans orf19.806 ORF VMA7 CAL0002611 PMID: 15870472|CGD_REF: CAL0082691 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.806 ORF VMA7 CAL0002611 PMID: 15870472|CGD_REF: CAL0082691 homozygous diploid, classical genetics null Not recorded virulence: absent mouse intravenous infection C. albicans orf19.807 ORF CHS5 CAL0002612 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: decreased growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.807 ORF CHS5 CAL0002612 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: abnormal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.807 ORF CHS5 CAL0002612 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.807 ORF CHS5 CAL0002612 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.808 ORF CAL0002613 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.809 ORF CAL0002615 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.811 ORF CAL0002642 PMID: 14663094|CGD_REF: CAL0080633 homozygous diploid, systematic mutation set (homozygous insertion mutants generated with URA3-ARG4-URA3 (UAU1) cassette) null BWP17 viable C. albicans orf19.811 ORF CAL0002642 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient SC medium C. albicans orf19.811 ORF CAL0002642 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient YNB medium C. albicans orf19.813 ORF CAL0002644 PMID: 14663094|CGD_REF: CAL0080633 homozygous diploid, systematic mutation set (homozygous insertion mutants generated with URA3-ARG4-URA3 (UAU1) cassette) null BWP17 viable C. albicans orf19.814 ORF SSY1 CAL0002645 PMID: 14871944|CGD_REF: CAL0081091 homozygous diploid, classical genetics null Not recorded resistance to chemicals: increased L-glutamic acid gamma-hydrazide C. albicans orf19.814 ORF SSY1 CAL0002645 PMID: 14871944|CGD_REF: CAL0081091 heterozygous diploid, classical genetics null Not recorded small molecule transport: normal histidine-activated amino acid transport C. albicans orf19.814 ORF SSY1 CAL0002645 PMID: 14871944|CGD_REF: CAL0081091 homozygous diploid, classical genetics null Not recorded small molecule transport: abnormal histidine-activated amino acid transport is blocked C. albicans orf19.814 ORF SSY1 CAL0002645 PMID: 16227594|CGD_REF: CAL0114869 homozygous diploid, classical genetics null Not recorded protein/peptide modification: absent Stp2p and Stp3p are not proteolytically processed in response to amino acids, as in wild type Stp2p C. albicans orf19.814 ORF SSY1 CAL0002645 PMID: 14871944|CGD_REF: CAL0081091 homozygous diploid, classical genetics null BWP17 hyphal growth: decreased solid serum-containing or Lee's media C. albicans orf19.814 ORF SSY1 CAL0002645 PMID: 14871944|CGD_REF: CAL0081091 homozygous diploid, classical genetics null BWP17 hyphal growth: normal solid Spider, SLAD, or GlcNAc; liquid serum or Lee's media C. albicans orf19.814 ORF SSY1 CAL0002645 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.814 ORF SSY1 CAL0002645 PMID: 14663094|CGD_REF: CAL0080633 homozygous diploid, systematic mutation set (homozygous insertion mutants generated with URA3-ARG4-URA3 (UAU1) cassette) null BWP17 viable C. albicans orf19.814 ORF SSY1 CAL0002645 PMID: 14871944|CGD_REF: CAL0081091 heterozygous diploid, classical genetics null Not recorded viable C. albicans orf19.814 ORF SSY1 CAL0002645 PMID: 14871944|CGD_REF: CAL0081091 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.815 ORF DCK1 CAL0002646 PMID: 12773383|CGD_REF: CAL0087974 heterozygous diploid, classical genetics (haploinsufficient phenotype assay) null CAI-4 filamentous growth: decreased solid Spider medium heterozygous transposon insertion C. albicans orf19.815 ORF DCK1 CAL0002646 PMID: 18579689|CGD_REF: CAL0119304 homozygous diploid, classical genetics null BWP17 invasive growth: absent C. albicans orf19.815 ORF DCK1 CAL0002646 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.815 ORF DCK1 CAL0002646 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: abnormal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.815 ORF DCK1 CAL0002646 PMID: 12773383|CGD_REF: CAL0087974 heterozygous diploid, classical genetics (haploinsufficient phenotype assay) null CAI-4 viable heterozygous transposon insertion C. albicans orf19.815 ORF DCK1 CAL0002646 PMID: 18579689|CGD_REF: CAL0119304 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.815 ORF DCK1 CAL0002646 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.815 ORF DCK1 CAL0002646 PMID: 20444104|CGD_REF: CAL0125731 homozygous diploid, classical genetics null BWP17 resistance to chemicals: decreased Calcofluor White C. albicans orf19.815 ORF DCK1 CAL0002646 PMID: 20444104|CGD_REF: CAL0125731 homozygous diploid, classical genetics null BWP17 resistance to chemicals: decreased Congo Red C. albicans orf19.815 ORF DCK1 CAL0002646 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.816 ORF DCK2 CAL0002647 PMID: 12773383|CGD_REF: CAL0087974 heterozygous diploid, classical genetics (haploinsufficient phenotype assay) null CAI-4 filamentous growth: decreased solid Spider medium heterozygous transposon insertion C. albicans orf19.816 ORF DCK2 CAL0002647 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.816 ORF DCK2 CAL0002647 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.816 ORF DCK2 CAL0002647 PMID: 12773383|CGD_REF: CAL0087974 heterozygous diploid, classical genetics (haploinsufficient phenotype assay) null CAI-4 viable heterozygous transposon insertion C. albicans orf19.816 ORF DCK2 CAL0002647 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.816 ORF DCK2 CAL0002647 PMID: 18579689|CGD_REF: CAL0119304 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.816 ORF DCK2 CAL0002647 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.816 ORF DCK2 CAL0002647 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.816 ORF DCK2 CAL0002647 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 invasive growth: decreased solid SLAD media C. albicans orf19.819 ORF CAL0002651 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.822 ORF HSP21 CAL0002678 PMID: 19187560|CGD_REF: CAL0122338 homozygous diploid, classical genetics null SC5314 biofilm formation: abnormal forms biofilm with altered detachment properties C. albicans orf19.822 ORF HSP21 CAL0002678 PMID: 22685587|CGD_REF: CAL0000157456 homozygous diploid, classical genetics null BWP17 viable C. albicans orf19.822 ORF HSP21 CAL0002678 PMID: 22685587|CGD_REF: CAL0000157456 homozygous diploid, classical genetics null BWP17 thermotolerance: decreased C. albicans orf19.822 ORF HSP21 CAL0002678 PMID: 22685587|CGD_REF: CAL0000157456 homozygous diploid, classical genetics null BWP17 oxidative stress resistance: decreased menadione C. albicans orf19.822 ORF HSP21 CAL0002678 PMID: 22685587|CGD_REF: CAL0000157456 homozygous diploid, classical genetics null BWP17 starvation resistance: decreased C. albicans orf19.822 ORF HSP21 CAL0002678 PMID: 22685587|CGD_REF: CAL0000157456 homozygous diploid, classical genetics null BWP17 hyphal growth: decreased C. albicans orf19.822 ORF HSP21 CAL0002678 PMID: 22685587|CGD_REF: CAL0000157456 homozygous diploid, classical genetics null BWP17 invasive growth: decreased C. albicans orf19.822 ORF HSP21 CAL0002678 PMID: 22685587|CGD_REF: CAL0000157456 homozygous diploid, classical genetics null BWP17 virulence: decreased other model (hen egg model) C. albicans orf19.822 ORF HSP21 CAL0002678 PMID: 23533680|CGD_REF: CAL0000158764 homozygous diploid, classical genetics null BWP17 resistance to chemicals: decreased ethanol (5%) C. albicans orf19.822 ORF HSP21 CAL0002678 PMID: 23533680|CGD_REF: CAL0000158764 homozygous diploid, classical genetics null BWP17 resistance to chemicals: decreased tacrolimus (anhydrous) C. albicans orf19.825 ORF GCD7 CAL0002680 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.826 ORF MED1 CAL0002681 PMID: 23873866|CGD_REF: CAL0000172574 homozygous diploid, classical genetics null SN152 phenotypic switching: abnormal C. albicans orf19.827 ORF CAL0002683 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 invasive growth: decreased solid SLAD media C. albicans orf19.829 ORF SCH9 CAL0002687 PMID: 14663094|CGD_REF: CAL0080633 homozygous diploid, systematic mutation set (homozygous insertion mutants generated with URA3-ARG4-URA3 (UAU1) cassette) null BWP17 hyphal growth: absent embedded in solid medium C. albicans orf19.829 ORF SCH9 CAL0002687 PMID: 14663094|CGD_REF: CAL0080633 homozygous diploid, systematic mutation set (homozygous insertion mutants generated with URA3-ARG4-URA3 (UAU1) cassette) null BWP17 chlamydospore formation: absent C. albicans orf19.829 ORF SCH9 CAL0002687 PMID: 21335533|CGD_REF: CAL0141646 homozygous diploid, classical genetics null sch9::hisG/sch9::hisG CAI-4 viable C. albicans orf19.829 ORF SCH9 CAL0002687 PMID: 21335533|CGD_REF: CAL0141646 homozygous diploid, classical genetics null sch9::hisG/sch9::hisG CAI-4 hyphal growth: increased under hypoxia at elevated CO2 levels at lower temperatures C. albicans orf19.829 ORF SCH9 CAL0002687 PMID: 21335533|CGD_REF: CAL0141646 homozygous diploid, classical genetics null sch9::hisG/sch9::hisG CAI-4 resistance to chemicals: increased fluconazole C. albicans orf19.829 ORF SCH9 CAL0002687 PMID: 21335533|CGD_REF: CAL0141646 homozygous diploid, classical genetics null sch9::hisG/sch9::hisG CAI-4 resistance to chemicals: increased sodium dodecyl sulfate C. albicans orf19.829 ORF SCH9 CAL0002687 PMID: 21335533|CGD_REF: CAL0141646 homozygous diploid, classical genetics null sch9::hisG/sch9::hisG CAI-4 resistance to chemicals: decreased hygromycin B C. albicans orf19.829 ORF SCH9 CAL0002687 PMID: 21335533|CGD_REF: CAL0141646 homozygous diploid, classical genetics null sch9::hisG/sch9::hisG CAI-4 chronological lifespan: decreased under normal oxygen levels C. albicans orf19.829 ORF SCH9 CAL0002687 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.829 ORF SCH9 CAL0002687 PMID: 14663094|CGD_REF: CAL0080633 homozygous diploid, systematic mutation set (homozygous insertion mutants generated with URA3-ARG4-URA3 (UAU1) cassette) null BWP17 viable C. albicans orf19.829 ORF SCH9 CAL0002687 PMID: 17241762|CGD_REF: CAL0117323 homozygous diploid, classical genetics null Not recorded virulence: decreased mouse corneal infection C. albicans orf19.829 ORF SCH9 CAL0002687 PMID: 20345900|CGD_REF: CAL0125167 homozygous diploid, classical genetics null RM1000 viable C. albicans orf19.829 ORF SCH9 CAL0002687 PMID: 20345900|CGD_REF: CAL0125167 heterozygous diploid, classical genetics null RM1000 viable C. albicans orf19.829 ORF SCH9 CAL0002687 PMID: 20345900|CGD_REF: CAL0125167 homozygous diploid, classical genetics null RM1000 growth in exponential phase: decreased rate C. albicans orf19.829 ORF SCH9 CAL0002687 PMID: 20345900|CGD_REF: CAL0125167 homozygous diploid, classical genetics null RM1000 cell size: decreased C. albicans orf19.829 ORF SCH9 CAL0002687 PMID: 20345900|CGD_REF: CAL0125167 homozygous diploid, classical genetics null RM1000 resistance to chemicals: decreased rapamycin (15 ng/l) C. albicans orf19.829 ORF SCH9 CAL0002687 PMID: 20345900|CGD_REF: CAL0125167 homozygous diploid, classical genetics null RM1000 resistance to chemicals: decreased caffeine (5 mM) C. albicans orf19.829 ORF SCH9 CAL0002687 PMID: 20345900|CGD_REF: CAL0125167 homozygous diploid, classical genetics null RM1000 ionic stress resistance: decreased lithium chloride (0.4 M) C. albicans orf19.829 ORF SCH9 CAL0002687 PMID: 20345900|CGD_REF: CAL0125167 homozygous diploid, classical genetics null RM1000 ionic stress resistance: decreased sodium chloride (1.5 M) C. albicans orf19.829 ORF SCH9 CAL0002687 PMID: 20345900|CGD_REF: CAL0125167 homozygous diploid, classical genetics null RM1000 ionic stress resistance: decreased potassium chloride (2 M) C. albicans orf19.829 ORF SCH9 CAL0002687 PMID: 20345900|CGD_REF: CAL0125167 homozygous diploid, classical genetics null RM1000 resistance to chemicals: decreased sodium dodecyl sulfate (0.01%) C. albicans orf19.829 ORF SCH9 CAL0002687 PMID: 20345900|CGD_REF: CAL0125167 homozygous diploid, classical genetics null RM1000 filamentous growth: decreased rate liquid Lee's medium C. albicans orf19.829 ORF SCH9 CAL0002687 PMID: 20345900|CGD_REF: CAL0125167 homozygous diploid, classical genetics null RM1000 filamentous growth: increased liquid SLAD medium 29.3% of mutant cells produce filaments, in comparison to 6.7% of wild-type cells C. albicans orf19.829 ORF SCH9 CAL0002687 PMID: 20345900|CGD_REF: CAL0125167 homozygous diploid, classical genetics null RM1000 hyphal growth: decreased solid Spider medium C. albicans orf19.829 ORF SCH9 CAL0002687 PMID: 20345900|CGD_REF: CAL0125167 homozygous diploid, classical genetics null RM1000 virulence: decreased hyphae are not observed in kidneys of infected mice mouse intravenous infection C. albicans orf19.829 ORF SCH9 CAL0002687 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 invasive growth: decreased solid SLAD media C. albicans orf19.831 ORF CAL0002711 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.832 ORF GPI13 CAL0002712 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.834 ORF CAL0002714 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.835 ORF CAL0002715 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.836 ORF CAL0002716 PMID: 12524333|CGD_REF: CAL0080691 homozygous diploid, systematic mutation set (homozygous insertion mutants generated with URA3-ARG4-URA3 (UAU1) cassette) null BWP17 inviable homozygous null mutant strain could not be recovered, suggesting that the gene is essential under the selection conditions C. albicans orf19.837 ORF GNA1 CAL0002717 PMID: 10878139|CGD_REF: CAL0081355 homozygous diploid, classical genetics null gna1::hisG/gna1::hisG?URA3?hisG CAI-4 nutrient uptake: absent N-acetyl-D-glucosamine C. albicans orf19.837 ORF GNA1 CAL0002717 PMID: 10878139|CGD_REF: CAL0081355 homozygous diploid, classical genetics null gna1::hisG/gna1::hisG?URA3?hisG CAI-4 cellular morphology: abnormal cell swelling and cell separation defects upon GlcNAc depletion C. albicans orf19.837 ORF GNA1 CAL0002717 PMID: 10878139|CGD_REF: CAL0081355 homozygous diploid, classical genetics null gna1::hisG/gna1::hisG?URA3?hisG CAI-4 viable C. albicans orf19.837 ORF GNA1 CAL0002717 PMID: 10878139|CGD_REF: CAL0081355 homozygous diploid, classical genetics null gna1::hisG/gna1::hisG?URA3?hisG CAI-4 virulence: decreased severely decreased virulence mouse intravenous infection C. albicans orf19.837 ORF GNA1 CAL0002717 PMID: 10878139|CGD_REF: CAL0081355 heterozygous diploid, classical genetics null gna1::hisG?URA3?hisG/GNA1 CAI-4 viable C. albicans orf19.837 ORF GNA1 CAL0002717 PMID: 10878139|CGD_REF: CAL0081355 heterozygous diploid, classical genetics null gna1::hisG?URA3?hisG/GNA1 CAI-4 virulence: decreased mouse intravenous infection C. albicans orf19.837 ORF GNA1 CAL0002717 PMID: 14507372|CGD_REF: CAL0088818 heterozygous diploid, large-scale survey (large-scale identification of essential genes by gene replacement and conditional expression (GRACE) method) repressible CAI-4 inviable one allele is deleted and the other is placed under repressible Tet promoter C. albicans orf19.837 ORF GNA1 CAL0002717 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.837 ORF GNA1 CAL0002717 PMID: 21135205|CGD_REF: CAL0139967 heterozygous diploid, competitive growth (large-scale identification of genes essential for virulence in mouse) repressible CAI-4 virulence: decreased mouse intravenous infection C. albicans orf19.837.1 ORF INO4 CAF0007452 PMID: 17588177|CGD_REF: CAL0118322 homozygous diploid, classical genetics null Not recorded inviable homozygous null mutant strain could not be recovered, suggesting that the gene is essential under the selection conditions C. albicans orf19.838.1 ORF RPS9B CAF0006912 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.839 ORF CAL0002720 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, competitive growth (haploinsufficient phenotype assay, barcode deletion set) null SC5314 resistance to chemicals: decreased Aureobasidin A C. albicans orf19.839 ORF CAL0002720 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.839 ORF CAL0002720 PMID: 20494978|CGD_REF: CAL0125636 heterozygous diploid, classical genetics null BWP17 resistance to chemicals: decreased clotrimazole (75 uM) growth in liquid culture confirmation of mutant phenotypes for heterozygous transposon insertion strains showing sensitivity in a large-scale assay C. albicans orf19.839 ORF CAL0002720 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 invasive growth: decreased solid SLAD media C. albicans orf19.843 ORF CAL0002750 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.843 ORF CAL0002750 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.843 ORF CAL0002750 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.843 ORF CAL0002750 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.843 ORF CAL0002750 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.844 ORF STE11 CAL0002751 PMID: 17804815|CGD_REF: CAL0118617 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased Calcofluor White C. albicans orf19.844 ORF STE11 CAL0002751 PMID: 17804815|CGD_REF: CAL0118617 homozygous diploid, classical genetics null Not recorded osmotic stress resistance: normal C. albicans orf19.844 ORF STE11 CAL0002751 PMID: 17804815|CGD_REF: CAL0118617 homozygous diploid, classical genetics null Not recorded oxidative stress resistance: normal C. albicans orf19.844 ORF STE11 CAL0002751 PMID: 21249169|CGD_REF: CAL0141189 heterozygous diploid, classical genetics reduction of function STE11-E707K (mutation prevents interaction with Hst7p) Other C. albicans mating efficiency: decreased C. albicans orf19.844 ORF STE11 CAL0002751 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: increased growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.844 ORF STE11 CAL0002751 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.844 ORF STE11 CAL0002751 PMID: 17804815|CGD_REF: CAL0118617 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.844 ORF STE11 CAL0002751 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: abnormal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.844 ORF STE11 CAL0002751 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.844 ORF STE11 CAL0002751 PMID: 20140194|CGD_REF: CAL0124995 homozygous diploid, classical genetics null Other C. albicans oxidative stress resistance: decreased hydrogen peroxide C. albicans orf19.844 ORF STE11 CAL0002751 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.846 ORF CAL0002752 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.846 ORF CAL0002752 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.846 ORF CAL0002752 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.846 ORF CAL0002752 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.848 ORF PGA16 CAL0002755 PMID: 24610660|CGD_REF: CAL0000173793 homozygous diploid, classical genetics null BWP17 virulence: decreased mouse intravenous infection C. albicans orf19.848 ORF PGA16 CAL0002755 PMID: 24610660|CGD_REF: CAL0000173793 homozygous diploid, classical genetics null BWP17 hyphal growth: abnormal fewer secondary hyphae and branches C. albicans orf19.848 ORF PGA16 CAL0002755 PMID: 24610660|CGD_REF: CAL0000173793 homozygous diploid, classical genetics null BWP17 viable C. albicans orf19.85 ORF GPX2 CAL0000682 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.85 ORF GPX2 CAL0000682 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient YNB medium C. albicans orf19.85 ORF GPX2 CAL0000682 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient SLAD medium C. albicans orf19.850 ORF CAL0002774 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.851 ORF CAL0002775 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.851 ORF CAL0002775 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 invasive growth: decreased solid SLAD media C. albicans orf19.852 ORF SAP98 CAL0002776 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.852 ORF SAP98 CAL0002776 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.852 ORF SAP98 CAL0002776 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.852 ORF SAP98 CAL0002776 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.854 ORF UGA11 CAL0002778 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.856 ORF IFK2 CAL0002780 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.856 ORF IFK2 CAL0002780 PMID: 14663094|CGD_REF: CAL0080633 homozygous diploid, systematic mutation set (homozygous insertion mutants generated with URA3-ARG4-URA3 (UAU1) cassette) null BWP17 viable C. albicans orf19.857 ORF FMO2 CAL0002782 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.86 ORF CAL0000683 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.86 ORF CAL0000683 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 invasive growth: decreased solid SLAD media C. albicans orf19.860 ORF BMT8 CAL0002804 PMID: 18234669|CGD_REF: CAL0119018 homozygous diploid, classical genetics null Not recorded resistance to chemicals: normal Calcofluor White C. albicans orf19.860 ORF BMT8 CAL0002804 PMID: 18234669|CGD_REF: CAL0119018 homozygous diploid, classical genetics null Not recorded resistance to chemicals: normal sodium dodecyl sulfate C. albicans orf19.860 ORF BMT8 CAL0002804 PMID: 18234669|CGD_REF: CAL0119018 homozygous diploid, classical genetics null BWP17 hyphal growth: normal serum-containing medium C. albicans orf19.860 ORF BMT8 CAL0002804 PMID: 18234669|CGD_REF: CAL0119018 homozygous diploid, classical genetics null Not recorded chlamydospore formation: normal RAT medium C. albicans orf19.860 ORF BMT8 CAL0002804 PMID: 18234669|CGD_REF: CAL0119018 homozygous diploid, classical genetics null Not recorded ionic stress resistance: normal sodium chloride C. albicans orf19.860 ORF BMT8 CAL0002804 PMID: 20141603|CGD_REF: CAL0124951 homozygous diploid, systematic mutation set (homozygous insertion mutants generated with URA3-ARG4-URA3 (UAU1) cassette) reduction of function BWP17 colony appearance: abnormal 10% serum or Spider media at 37 deg C transposon insertion is 553 bp upstream of the translational start codon; colonies are smoother than wild type but mutant is able to form true hyphae under liquid inducing conditions C. albicans orf19.860 ORF BMT8 CAL0002804 PMID: 18234669|CGD_REF: CAL0119018 homozygous diploid, classical genetics null Not recorded resistance to chemicals: normal calcium dichloride C. albicans orf19.860 ORF BMT8 CAL0002804 PMID: 18234669|CGD_REF: CAL0119018 homozygous diploid, classical genetics null Not recorded viable rich medium wild-type growth rate C. albicans orf19.860 ORF BMT8 CAL0002804 PMID: 20141603|CGD_REF: CAL0124951 homozygous diploid, systematic mutation set (homozygous insertion mutants generated with URA3-ARG4-URA3 (UAU1) cassette) reduction of function BWP17 viable transposon insertion is 553 bp upstream of the translational start codon C. albicans orf19.862 ORF CAL0002808 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 invasive growth: decreased solid SLAD media C. albicans orf19.863 ORF CAL0002812 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.864 ORF CAL0002815 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.866 ORF RAD32 CAL0002818 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.87 ORF GPX1 CAL0000684 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.872 ORF CAL0002850 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.872 ORF CAL0002850 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.872 ORF CAL0002850 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.872 ORF CAL0002850 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.873 ORF CAL0002853 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.875 ORF CAL0002858 PMID: 20141603|CGD_REF: CAL0124951 homozygous diploid, systematic mutation set (homozygous insertion mutants generated with URA3-ARG4-URA3 (UAU1) cassette) null BWP17 respiratory growth: absent glycerol C. albicans orf19.875 ORF CAL0002858 PMID: 20141603|CGD_REF: CAL0124951 homozygous diploid, systematic mutation set (homozygous insertion mutants generated with URA3-ARG4-URA3 (UAU1) cassette) null BWP17 viable C. albicans orf19.876 ORF PGA33 CAL0002859 PMID: 18765290|CGD_REF: CAL0119430 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.878 ORF NBN1 CAL0002865 PMID: 18685084|CGD_REF: CAL0119364 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased camptothecin C. albicans orf19.878 ORF NBN1 CAL0002865 PMID: 18685084|CGD_REF: CAL0119364 homozygous diploid, classical genetics null Not recorded vegetative growth: decreased rate C. albicans orf19.878 ORF NBN1 CAL0002865 PMID: 18685084|CGD_REF: CAL0119364 homozygous diploid, classical genetics null BWP17 hyphal growth: decreased severe decrease C. albicans orf19.878 ORF NBN1 CAL0002865 PMID: 18685084|CGD_REF: CAL0119364 homozygous diploid, classical genetics null Not recorded cellular morphology: abnormal cells are enlarged and multibudded C. albicans orf19.878 ORF NBN1 CAL0002865 PMID: 18685084|CGD_REF: CAL0119364 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased methyl methanesulfonate C. albicans orf19.878 ORF NBN1 CAL0002865 PMID: 18685084|CGD_REF: CAL0119364 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased hydroxyurea C. albicans orf19.878 ORF NBN1 CAL0002865 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.878 ORF NBN1 CAL0002865 PMID: 18685084|CGD_REF: CAL0119364 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.878 ORF NBN1 CAL0002865 PMID: 20494978|CGD_REF: CAL0125636 heterozygous diploid, classical genetics null BWP17 resistance to chemicals: decreased clotrimazole (75 uM) growth in liquid culture confirmation of mutant phenotypes for heterozygous transposon insertion strains showing sensitivity in a large-scale assay C. albicans orf19.88 ORF ILV5 CAL0000685 PMID: 21135205|CGD_REF: CAL0139967 heterozygous diploid, competitive growth (large-scale identification of genes essential for virulence in mouse) repressible CAI-4 virulence: normal mouse intravenous infection C. albicans orf19.88 ORF ILV5 CAL0000685 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.880 ORF CAL0002889 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.881 ORF DFG16 CAL0002891 PMID: 15879523|CGD_REF: CAL0082749 homozygous diploid, classical genetics null BWP17 filamentous growth: absent solid pH 8 media abolished peripheral filaments C. albicans orf19.881 ORF DFG16 CAL0002891 PMID: 17367383|CGD_REF: CAL0117481 homozygous diploid, classical genetics null CAI-4 filamentous growth: absent solid media at pH 8 C. albicans orf19.881 ORF DFG16 CAL0002891 PMID: 17367383|CGD_REF: CAL0117481 homozygous diploid, classical genetics null Not recorded utilization of iron source: decreased pH 8 poor growth under iron-limiting conditions C. albicans orf19.881 ORF DFG16 CAL0002891 PMID: 17367383|CGD_REF: CAL0117481 homozygous diploid, classical genetics null Not recorded utilization of phosphorus source: decreased low phosphate conditions at pH 8 or pH 7.4 no growth C. albicans orf19.881 ORF DFG16 CAL0002891 PMID: 15879523|CGD_REF: CAL0082749 homozygous diploid, classical genetics null Not recorded endomembrane system morphology: normal multivesicular body (MVB) morphology visualized by FM4-64 staining in live cells C. albicans orf19.881 ORF DFG16 CAL0002891 PMID: 22427429|CGD_REF: CAL0000156990 homozygous diploid, classical genetics null BWP17 protein/peptide modification: absent mutants don't process RIM8-HA RIM8-HA C. albicans orf19.881 ORF DFG16 CAL0002891 PMID: 15879523|CGD_REF: CAL0082749 heterozygous diploid, classical genetics null Not recorded viable C. albicans orf19.881 ORF DFG16 CAL0002891 PMID: 15879523|CGD_REF: CAL0082749 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.881 ORF DFG16 CAL0002891 PMID: 17367383|CGD_REF: CAL0117481 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.881 ORF DFG16 CAL0002891 PMID: 17367383|CGD_REF: CAL0117481 homozygous diploid, classical genetics null Not recorded virulence: decreased mouse intravenous infection C. albicans orf19.886 ORF PAN1 CAL0002900 PMID: 17431925|CGD_REF: CAL0117929 heterozygous diploid, classical genetics repressible Not recorded cell shape: abnormal round and swollen cells upon depletion C. albicans orf19.886 ORF PAN1 CAL0002900 PMID: 17431925|CGD_REF: CAL0117929 homozygous diploid, classical genetics null Not recorded inviable homozygous null mutant strain could not be recovered, suggesting that the gene is essential under the selection conditions C. albicans orf19.886 ORF PAN1 CAL0002900 PMID: 17431925|CGD_REF: CAL0117929 heterozygous diploid, classical genetics repressible Not recorded endocytosis: decreased strong defect in uptake of FM4-64 C. albicans orf19.886 ORF PAN1 CAL0002900 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.889 ORF THI20 CAL0002907 PMID: 15964282|CGD_REF: CAL0114274 homozygous diploid, systematic mutation set (split-marker transposon insertion strategy to disrupt both alleles) null BWP17 biofilm formation: normal C. albicans orf19.889 ORF THI20 CAL0002907 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.889 ORF THI20 CAL0002907 PMID: 15964282|CGD_REF: CAL0114274 homozygous diploid, systematic mutation set (split-marker transposon insertion strategy to disrupt both alleles) null BWP17 viable C. albicans orf19.89 ORF PEX7 CAL0000686 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.891 ORF CAL0002924 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.893 ORF PGA17 CAL0002926 PMID: 17873081|CGD_REF: CAL0118685 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.893 ORF PGA17 CAL0002926 PMID: 18765290|CGD_REF: CAL0119430 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.895 ORF HOG1 CAL0002931 PMID: 16339080|CGD_REF: CAL0115439 homozygous diploid, classical genetics null BWP17 filamentous growth: abnormal displays hyphal and pseudohyphal growth under noninducing conditions C. albicans orf19.895 ORF HOG1 CAL0002931 PMID: 16467475|CGD_REF: CAL0115509 homozygous diploid, classical genetics null RM1000 filamentous growth: increased low pH or low temperature C. albicans orf19.895 ORF HOG1 CAL0002931 PMID: 19202089|CGD_REF: CAL0122349 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased sodium azide C. albicans orf19.895 ORF HOG1 CAL0002931 PMID: 19202089|CGD_REF: CAL0122349 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased oligomycin C. albicans orf19.895 ORF HOG1 CAL0002931 PMID: 17804815|CGD_REF: CAL0118617 homozygous diploid, classical genetics null Not recorded resistance to chemicals: increased Calcofluor White C. albicans orf19.895 ORF HOG1 CAL0002931 PMID: 16151209|CGD_REF: CAL0114691 homozygous diploid, classical genetics null Not recorded heat sensitivity: normal C. albicans orf19.895 ORF HOG1 CAL0002931 PMID: 12684384|CGD_REF: CAL0080816 homozygous diploid, classical genetics null Not recorded UV resistance: decreased C. albicans orf19.895 ORF HOG1 CAL0002931 PMID: 16467475|CGD_REF: CAL0115509 homozygous diploid, classical genetics null Not recorded protein/peptide modification: increased Cek1p basal level of phosphorylation is increased Cek1p C. albicans orf19.895 ORF HOG1 CAL0002931 PMID: 16079350|CGD_REF: CAL0114435 homozygous diploid, classical genetics null Not recorded protein/peptide modification: abnormal defect in phosphorylation of Mkc1p in response to calcium, sorbitol or glycerol; increased phosphorylation in response to cell-wall disrupting agents Mkc1p C. albicans orf19.895 ORF HOG1 CAL0002931 PMID: 18625027|CGD_REF: CAL0119338 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased rapamycin C. albicans orf19.895 ORF HOG1 CAL0002931 PMID: 10322006|CGD_REF: CAL0081392 homozygous diploid, classical genetics null Not recorded hyphal growth: increased increased hyphal growth at limiting serum concentrations C. albicans orf19.895 ORF HOG1 CAL0002931 PMID: 15817773|CGD_REF: CAL0104043 homozygous diploid, classical genetics null RM1000 invasive growth: increased solid SLAD medium C. albicans orf19.895 ORF HOG1 CAL0002931 PMID: 15229284|CGD_REF: CAL0082098 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased staurosporine C. albicans orf19.895 ORF HOG1 CAL0002931 PMID: 17804815|CGD_REF: CAL0118617 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased staurosporine C. albicans orf19.895 ORF HOG1 CAL0002931 PMID: 16339080|CGD_REF: CAL0115439 homozygous diploid, classical genetics null Not recorded oxidative stress resistance: decreased hydrogen peroxide increased sensitivity to high-dose peroxide stress, but not low-dose peroxide stress C. albicans orf19.895 ORF HOG1 CAL0002931 PMID: 15817773|CGD_REF: CAL0104043 homozygous diploid, classical genetics null Not recorded oxidative stress resistance: decreased hydrogen peroxide C. albicans orf19.895 ORF HOG1 CAL0002931 PMID: 17804815|CGD_REF: CAL0118617 homozygous diploid, classical genetics null Not recorded oxidative stress resistance: decreased hydrogen peroxide C. albicans orf19.895 ORF HOG1 CAL0002931 PMID: 19759180|CGD_REF: CAL0124252 homozygous diploid, classical genetics null Not recorded oxidative stress resistance: decreased hydrogen peroxide C. albicans orf19.895 ORF HOG1 CAL0002931 PMID: 12684384|CGD_REF: CAL0080816 homozygous diploid, classical genetics null Not recorded chlamydospore formation: absent C. albicans orf19.895 ORF HOG1 CAL0002931 PMID: 16467475|CGD_REF: CAL0115509 homozygous diploid, classical genetics null Not recorded chlamydospore formation: absent C. albicans orf19.895 ORF HOG1 CAL0002931 PMID: 12684384|CGD_REF: CAL0080816 homozygous diploid, classical genetics null Not recorded osmotic stress resistance: decreased C. albicans orf19.895 ORF HOG1 CAL0002931 PMID: 15817773|CGD_REF: CAL0104043 homozygous diploid, classical genetics null Not recorded osmotic stress resistance: decreased C. albicans orf19.895 ORF HOG1 CAL0002931 PMID: 16151209|CGD_REF: CAL0114691 homozygous diploid, classical genetics null Not recorded osmotic stress resistance: decreased C. albicans orf19.895 ORF HOG1 CAL0002931 PMID: 16339080|CGD_REF: CAL0115439 homozygous diploid, classical genetics null Not recorded osmotic stress resistance: decreased C. albicans orf19.895 ORF HOG1 CAL0002931 PMID: 16467475|CGD_REF: CAL0115509 homozygous diploid, classical genetics null Not recorded osmotic stress resistance: decreased C. albicans orf19.895 ORF HOG1 CAL0002931 PMID: 8824643|CGD_REF: CAL0081390 homozygous diploid, classical genetics null Not recorded osmotic stress resistance: decreased C. albicans orf19.895 ORF HOG1 CAL0002931 PMID: 19202089|CGD_REF: CAL0122349 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased chloramphenicol C. albicans orf19.895 ORF HOG1 CAL0002931 PMID: 16151209|CGD_REF: CAL0114691 homozygous diploid, classical genetics null Not recorded chemical compound accumulation: decreased D-arabinitol C. albicans orf19.895 ORF HOG1 CAL0002931 PMID: 12684384|CGD_REF: CAL0080816 homozygous diploid, classical genetics null Not recorded oxidative stress resistance: decreased superoxide C. albicans orf19.895 ORF HOG1 CAL0002931 PMID: 15229284|CGD_REF: CAL0082098 homozygous diploid, classical genetics null Not recorded metal resistance: decreased cadmium C. albicans orf19.895 ORF HOG1 CAL0002931 PMID: 17804815|CGD_REF: CAL0118617 homozygous diploid, classical genetics null Not recorded metal resistance: decreased cadmium C. albicans orf19.895 ORF HOG1 CAL0002931 PMID: 17804815|CGD_REF: CAL0118617 homozygous diploid, classical genetics null Not recorded osmotic stress resistance: decreased sodium chloride C. albicans orf19.895 ORF HOG1 CAL0002931 PMID: 15229284|CGD_REF: CAL0082098 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased arsenic C. albicans orf19.895 ORF HOG1 CAL0002931 PMID: 17804815|CGD_REF: CAL0118617 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased arsenic C. albicans orf19.895 ORF HOG1 CAL0002931 PMID: 15229284|CGD_REF: CAL0082098 homozygous diploid, classical genetics null Not recorded oxidative stress resistance: decreased tert-butyl hydroperoxide C. albicans orf19.895 ORF HOG1 CAL0002931 PMID: 17804815|CGD_REF: CAL0118617 homozygous diploid, classical genetics null Not recorded oxidative stress resistance: decreased tert-butyl hydroperoxide C. albicans orf19.895 ORF HOG1 CAL0002931 PMID: 16151209|CGD_REF: CAL0114691 homozygous diploid, classical genetics null Not recorded oxidative stress resistance: decreased C. albicans orf19.895 ORF HOG1 CAL0002931 PMID: 16467475|CGD_REF: CAL0115509 homozygous diploid, classical genetics null Not recorded oxidative stress resistance: decreased C. albicans orf19.895 ORF HOG1 CAL0002931 PMID: 15229284|CGD_REF: CAL0082098 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased caffeine C. albicans orf19.895 ORF HOG1 CAL0002931 PMID: 17804815|CGD_REF: CAL0118617 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased caffeine C. albicans orf19.895 ORF HOG1 CAL0002931 PMID: 15229284|CGD_REF: CAL0082098 homozygous diploid, classical genetics null Not recorded oxidative stress resistance: decreased menadione C. albicans orf19.895 ORF HOG1 CAL0002931 PMID: 15817773|CGD_REF: CAL0104043 homozygous diploid, classical genetics null Not recorded oxidative stress resistance: decreased menadione C. albicans orf19.895 ORF HOG1 CAL0002931 PMID: 17804815|CGD_REF: CAL0118617 homozygous diploid, classical genetics null Not recorded oxidative stress resistance: decreased menadione C. albicans orf19.895 ORF HOG1 CAL0002931 PMID: 16151209|CGD_REF: CAL0114691 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased citric acid increased sensitivity to citric acid stress; also displays decreased glycerol and increased D-arabitol production C. albicans orf19.895 ORF HOG1 CAL0002931 PMID: 15229284|CGD_REF: CAL0082098 homozygous diploid, classical genetics null Not recorded osmotic stress resistance: decreased glucitol C. albicans orf19.895 ORF HOG1 CAL0002931 PMID: 17804815|CGD_REF: CAL0118617 homozygous diploid, classical genetics null Not recorded osmotic stress resistance: decreased glucitol C. albicans orf19.895 ORF HOG1 CAL0002931 PMID: 15229284|CGD_REF: CAL0082098 homozygous diploid, classical genetics null Not recorded hyperosmotic stress resistance: decreased potassium chloride C. albicans orf19.895 ORF HOG1 CAL0002931 PMID: 19202089|CGD_REF: CAL0122349 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased potassium cyanide C. albicans orf19.895 ORF HOG1 CAL0002931 PMID: 16467475|CGD_REF: CAL0115509 homozygous diploid, classical genetics null Not recorded chemical compound accumulation: abnormal glucan abnormal cell wall glucan content C. albicans orf19.895 ORF HOG1 CAL0002931 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: decreased growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.895 ORF HOG1 CAL0002931 PMID: 17346314|CGD_REF: CAL0118020 homozygous diploid, classical genetics null RM1000 resistance to killing by host cells: decreased 2 hrs at MOI 1:40 in vitro model of infection (HL-60 cells or RAW 264.7 macrophages) C. albicans orf19.895 ORF HOG1 CAL0002931 PMID: 17346314|CGD_REF: CAL0118020 homozygous diploid, classical genetics null RM1000 resistance to killing by host cells: decreased 2 hrs at MOI 1:40 in vitro model of infection (human PMN) C. albicans orf19.895 ORF HOG1 CAL0002931 PMID: 21994942|CGD_REF: CAL0000143465 homozygous diploid, classical genetics null hog1::loxP-ura3-loxP/hog1::loxP-HIS1-loxP (URA3 expressed from the RPS10 locus) RM1000 virulence: decreased 100% survival rate of mice infected with hog1 cells over the 28-day experiment mouse intravenous infection C. albicans orf19.895 ORF HOG1 CAL0002931 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.895 ORF HOG1 CAL0002931 PMID: 14507372|CGD_REF: CAL0088818 heterozygous diploid, large-scale survey (large-scale identification of essential genes by gene replacement and conditional expression (GRACE) method) repressible CAI-4 viable one allele is deleted and the other is placed under repressible Tet promoter C. albicans orf19.895 ORF HOG1 CAL0002931 PMID: 10322006|CGD_REF: CAL0081392 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.895 ORF HOG1 CAL0002931 PMID: 15229284|CGD_REF: CAL0082098 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.895 ORF HOG1 CAL0002931 PMID: 16151209|CGD_REF: CAL0114691 heterozygous diploid, classical genetics null Not recorded viable C. albicans orf19.895 ORF HOG1 CAL0002931 PMID: 16151209|CGD_REF: CAL0114691 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.895 ORF HOG1 CAL0002931 PMID: 8824643|CGD_REF: CAL0081390 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.895 ORF HOG1 CAL0002931 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: abnormal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.895 ORF HOG1 CAL0002931 PMID: 23261427|CGD_REF: CAL0000158305 homozygous diploid, classical genetics null RM1000 resistance to chemicals: decreased sodium chloride C. albicans orf19.895 ORF HOG1 CAL0002931 PMID: 23261427|CGD_REF: CAL0000158305 homozygous diploid, classical genetics null RM1000 chemical compound accumulation: decreased glycerol intracellular content of glycerol was extremely low in mutant C. albicans orf19.895 ORF HOG1 CAL0002931 PMID: 23856128|CGD_REF: CAL0000172540 homozygous diploid, classical genetics null BWP17 resistance to chemicals: decreased propolis C. albicans orf19.895 ORF HOG1 CAL0002931 PMID: 10322006|CGD_REF: CAL0081392 homozygous diploid, classical genetics null Not recorded virulence: decreased mouse intravenous infection C. albicans orf19.895 ORF HOG1 CAL0002931 PMID: 15378749|CGD_REF: CAL0082119 homozygous diploid, classical genetics null Not recorded virulence: decreased mouse intravenous infection C. albicans orf19.895 ORF HOG1 CAL0002931 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: decreased rate liquid synthetic complete medium C. albicans orf19.895 ORF HOG1 CAL0002931 PMID: 23689717|CGD_REF: CAL0000172329 homozygous diploid, classical genetics null Other C. albicans resistance to chemicals: decreased plant defensin NaD1 C. albicans orf19.895 ORF HOG1 CAL0002931 PMID: 23706023|CGD_REF: CAL0000172371 homozygous diploid, classical genetics null Other C. albicans resistance to phagocytosis: decreased decreased killing of J774.1 macrophages after 3 hrs C. albicans orf19.895 ORF HOG1 CAL0002931 PMID: 20118211|CGD_REF: CAL0125028 homozygous diploid, classical genetics null RM1000 oxidative stress resistance: decreased decreased H2O2 resistance C. albicans orf19.895 ORF HOG1 CAL0002931 PMID: 20140194|CGD_REF: CAL0124995 homozygous diploid, classical genetics null Other C. albicans oxidative stress resistance: decreased hydrogen peroxide C. albicans orf19.895 ORF HOG1 CAL0002931 PMID: 20140194|CGD_REF: CAL0124995 homozygous diploid, classical genetics null Other C. albicans resistance to chemicals: decreased fluconazole C. albicans orf19.895 ORF HOG1 CAL0002931 PMID: 20140194|CGD_REF: CAL0124995 homozygous diploid, classical genetics null Other C. albicans osmotic stress resistance: decreased sodium chloride C. albicans orf19.895 ORF HOG1 CAL0002931 PMID: 20608985|CGD_REF: CAL0125886 homozygous diploid, classical genetics null RM1000 resistance to chemicals: decreased menadione C. albicans orf19.895 ORF HOG1 CAL0002931 PMID: 20608985|CGD_REF: CAL0125886 homozygous diploid, classical genetics null RM1000 oxidative stress resistance: decreased menadione C. albicans orf19.895 ORF HOG1 CAL0002931 PMID: 20608985|CGD_REF: CAL0125886 homozygous diploid, classical genetics null RM1000 resistance to chemicals: decreased hydrogen peroxide C. albicans orf19.895 ORF HOG1 CAL0002931 PMID: 20608985|CGD_REF: CAL0125886 homozygous diploid, classical genetics null RM1000 oxidative stress resistance: decreased hydrogen peroxide C. albicans orf19.895 ORF HOG1 CAL0002931 PMID: 20608985|CGD_REF: CAL0125886 homozygous diploid, classical genetics null RM1000 chemical compound accumulation: increased trehalose C. albicans orf19.895 ORF HOG1 CAL0002931 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.896 ORF CHK1 CAL0002932 PMID: 17664325|CGD_REF: CAL0118482 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased fluconazole C. albicans orf19.896 ORF CHK1 CAL0002932 PMID: 10411270|CGD_REF: CAL0081382 heterozygous diploid, classical genetics null Not recorded flocculation: increased flocculence is less severe than that of homozygous null mutant C. albicans orf19.896 ORF CHK1 CAL0002932 PMID: 10411270|CGD_REF: CAL0081382 homozygous diploid, classical genetics null Not recorded flocculation: increased C. albicans orf19.896 ORF CHK1 CAL0002932 PMID: 19563901|CGD_REF: CAL0123856 homozygous diploid, classical genetics null Not recorded flocculation: increased C. albicans orf19.896 ORF CHK1 CAL0002932 PMID: 19563901|CGD_REF: CAL0123856 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased Calcofluor White C. albicans orf19.896 ORF CHK1 CAL0002932 PMID: 15302838|CGD_REF: CAL0082108 homozygous diploid, classical genetics null Not recorded germ tube formation: abnormal defect in farnesol-mediated inhibition of germination C. albicans orf19.896 ORF CHK1 CAL0002932 PMID: 15302838|CGD_REF: CAL0082108 heterozygous diploid, classical genetics null Not recorded germ tube formation: abnormal defect in farnesol-mediated inhibition of germination; phenotype is intermediate between wild type and that of the homozygous null mutant C. albicans orf19.896 ORF CHK1 CAL0002932 PMID: 15470110|CGD_REF: CAL0082464 homozygous diploid, classical genetics null Not recorded germ tube formation: normal serum-containing medium C. albicans orf19.896 ORF CHK1 CAL0002932 PMID: 10572127|CGD_REF: CAL0081384 homozygous diploid, classical genetics null chk1::hisG-URA3-hisG/chk1::hisG-URA3-hisG CAI-4 hyphal growth: decreased solid YEPD plus serum C. albicans orf19.896 ORF CHK1 CAL0002932 PMID: 10572127|CGD_REF: CAL0081384 homozygous diploid, classical genetics null chk1::hisG-URA3-hisG/chk1::hisG-URA3-hisG CAI-4 viable C. albicans orf19.896 ORF CHK1 CAL0002932 PMID: 10572127|CGD_REF: CAL0081384 homozygous diploid, classical genetics null chk1::hisG-URA3-hisG/chk1::hisG-URA3-hisG CAI-4 virulence: decreased mouse intravenous infection C. albicans orf19.896 ORF CHK1 CAL0002932 PMID: 17664325|CGD_REF: CAL0118482 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased voriconazole C. albicans orf19.896 ORF CHK1 CAL0002932 PMID: 15470110|CGD_REF: CAL0082464 homozygous diploid, classical genetics null Not recorded oxidative stress resistance: decreased hydrogen peroxide C. albicans orf19.896 ORF CHK1 CAL0002932 PMID: 19563901|CGD_REF: CAL0123856 homozygous diploid, classical genetics null Not recorded chemical compound accumulation: abnormal mannan altered cell wall mannan content C. albicans orf19.896 ORF CHK1 CAL0002932 PMID: 19563901|CGD_REF: CAL0123856 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased Congo Red C. albicans orf19.896 ORF CHK1 CAL0002932 PMID: 11796636|CGD_REF: CAL0080998 homozygous diploid, classical genetics null CAI-4 resistance to killing by host cells: decreased in vitro model of infection (human neutrophil culture) C. albicans orf19.896 ORF CHK1 CAL0002932 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.896 ORF CHK1 CAL0002932 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.896 ORF CHK1 CAL0002932 PMID: 11796636|CGD_REF: CAL0080998 homozygous diploid, classical genetics null CAI-4 resistance to killing by host cells: decreased approximately 81% killed compared to wild-type control 37% killed in vitro model of infection (human PMNs) C. albicans orf19.896 ORF CHK1 CAL0002932 PMID: 11796636|CGD_REF: CAL0080998 homozygous diploid, classical genetics null CAI-4 resistance to phagocytosis: normal in vitro model of infection (human PMNs) C. albicans orf19.896 ORF CHK1 CAL0002932 PMID: 20688824|CGD_REF: CAL0126005 homozygous diploid, classical genetics null chk1::HisG/chk1::HisG-URA3-HisG CAI-4 resistance to phagocytosis: decreased increased uptake as compared to CAF2-1 control strain in vitro model of infection (murine macrophage cell lines RAW264.7 and J-774A.1, murine and human PMN) C. albicans orf19.896 ORF CHK1 CAL0002932 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.896 ORF CHK1 CAL0002932 PMID: 14507372|CGD_REF: CAL0088818 heterozygous diploid, large-scale survey (large-scale identification of essential genes by gene replacement and conditional expression (GRACE) method) repressible CAI-4 viable one allele is deleted and the other is placed under repressible Tet promoter C. albicans orf19.896 ORF CHK1 CAL0002932 PMID: 10411270|CGD_REF: CAL0081382 heterozygous diploid, classical genetics null Not recorded viable C. albicans orf19.896 ORF CHK1 CAL0002932 PMID: 10411270|CGD_REF: CAL0081382 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.896 ORF CHK1 CAL0002932 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.896 ORF CHK1 CAL0002932 PMID: 15302838|CGD_REF: CAL0082108 homozygous diploid, classical genetics null CAF2-1 biofilm formation: abnormal defect in farnesol-mediated inhibition of biofilm formation C. albicans orf19.896 ORF CHK1 CAL0002932 PMID: 23563485|CGD_REF: CAL0000158903 homozygous diploid, classical genetics null a/alpha chk1::FRT/chk1::FRT SC5314 biofilm formation: abnormal RPMI medium 29 degrees C with rocking for 48 hr mutant has decreased thickness of basal poly yeast layer, a slight decrease in hypha production and vertical orientation of hyphae, partial impermeability to Sypro Ruby, complete penetrability by human PMNs and decreased fluconazole resistance C. albicans orf19.896 ORF CHK1 CAL0002932 PMID: 10417206|CGD_REF: CAL0081383 homozygous diploid, classical genetics null Not recorded virulence: absent mouse intravenous infection C. albicans orf19.896 ORF CHK1 CAL0002932 PMID: 10417206|CGD_REF: CAL0081383 heterozygous diploid, classical genetics null Not recorded virulence: decreased mouse intravenous infection C. albicans orf19.896 ORF CHK1 CAL0002932 PMID: 10417206|CGD_REF: CAL0081383 homozygous diploid, classical genetics null Not recorded virulence: normal rat vaginal infection C. albicans orf19.896 ORF CHK1 CAL0002932 PMID: 20118211|CGD_REF: CAL0125028 homozygous diploid, classical genetics null CAI-4 oxidative stress resistance: decreased decreased H2O2 resistance C. albicans orf19.896 ORF CHK1 CAL0002932 PMID: 20140194|CGD_REF: CAL0124995 homozygous diploid, classical genetics null Other C. albicans oxidative stress resistance: decreased hydrogen peroxide C. albicans orf19.896 ORF CHK1 CAL0002932 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.897 ORF VPS20 CAL0002935 PMID: 22427429|CGD_REF: CAL0000156990 homozygous diploid, classical genetics null BWP17 protein/peptide modification: absent mutants don't process RIM8-HA RIM8-HA C. albicans orf19.897 ORF VPS20 CAL0002935 PMID: 22427429|CGD_REF: CAL0000156990 homozygous diploid, classical genetics null BWP17 protein/peptide modification: absent Rim8-HA was not modified to the 95-105 kD forms in this mutant at pH 8 Rim8-HA C. albicans orf19.897 ORF VPS20 CAL0002935 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.897 ORF VPS20 CAL0002935 PMID: 22427429|CGD_REF: CAL0000156990 homozygous diploid, classical genetics null BWP17 protein/peptide modification: abnormal defective for RIM8-HA-processing RIM8-HA C. albicans orf19.897 ORF VPS20 CAL0002935 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient YPD medium C. albicans orf19.897 ORF VPS20 CAL0002935 PMID: 20581294|CGD_REF: CAL0125802 homozygous diploid, classical genetics null BWP17 alkaline pH resistance: decreased YPD pH 9, 2 days at 37 degrees C C. albicans orf19.897 ORF VPS20 CAL0002935 PMID: 20581294|CGD_REF: CAL0125802 homozygous diploid, classical genetics null BWP17 viable C. albicans orf19.897 ORF VPS20 CAL0002935 PMID: 20581294|CGD_REF: CAL0125802 homozygous diploid, classical genetics null BWP17 protein/peptide modification: absent Rim101p C. albicans orf19.897 ORF VPS20 CAL0002935 PMID: 20581294|CGD_REF: CAL0125802 homozygous diploid, classical genetics null BWP17 hyphal growth: absent M199 pH 8 plates, 37 degrees C, 6 days no peripheral hyphae produced C. albicans orf19.897 ORF VPS20 CAL0002935 PMID: 20581294|CGD_REF: CAL0125802 homozygous diploid, classical genetics null BWP17 metal resistance: decreased lithium chloride (150 mM) YPD plus 150 mM lithium chloride C. albicans orf19.897 ORF VPS20 CAL0002935 PMID: 20581294|CGD_REF: CAL0125802 homozygous diploid, classical genetics null BWP17 resistance to chemicals: decreased iron chelators YPD plus 150 micromolar bathophenanthrolinedisulfonic acid (BPS) C. albicans orf19.898 ORF HEM2 CAL0002938 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.899 ORF CAL0002941 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.899 ORF CAL0002941 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.899 ORF CAL0002941 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.899 ORF CAL0002941 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.9 ORF CAL0005251 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient YNB medium C. albicans orf19.9 ORF CAL0005251 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient SLAD medium C. albicans orf19.90 ORF CAL0000702 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.900 ORF NSP1 CAL0003573 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.900 ORF NSP1 CAL0003573 PMID: 21135205|CGD_REF: CAL0139967 heterozygous diploid, large-scale survey (large-scale identification of genes essential for virulence in mouse) repressible CAI-4 virulence: absent mouse intravenous infection C. albicans orf19.903 ORF GPM1 CAL0003574 PMID: 17959597|CGD_REF: CAL0118809 homozygous diploid, classical genetics null Not recorded utilization of carbon source: absent D-glucose grows on ethanol and glycerol C. albicans orf19.903 ORF GPM1 CAL0003574 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.903 ORF GPM1 CAL0003574 PMID: 17959597|CGD_REF: CAL0118809 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.903 ORF GPM1 CAL0003574 PMID: 24625558|CGD_REF: CAL0000173809 homozygous diploid, classical genetics null SC5314 adhesion: decreased low efficiency adhesion to human endothelial cells C. albicans orf19.904 ORF CAL0003575 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 invasive growth: decreased solid SLAD media C. albicans orf19.905 ORF AVT7 CAL0003576 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.906 ORF ROM2 CAL0003577 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.906 ORF ROM2 CAL0003577 PMID: 21135205|CGD_REF: CAL0139967 heterozygous diploid, competitive growth (large-scale identification of genes essential for virulence in mouse) repressible CAI-4 virulence: decreased mouse intravenous infection C. albicans orf19.908 ORF FEN12 CAL0003580 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.908 ORF FEN12 CAL0003580 PMID: 24395234|CGD_REF: CAL0000173748 homozygous diploid, classical genetics null SC5314 viable C. albicans orf19.908 ORF FEN12 CAL0003580 PMID: 24395234|CGD_REF: CAL0000173748 homozygous diploid, classical genetics null SC5314 resistance to chemicals: decreased amphotericin B C. albicans orf19.908 ORF FEN12 CAL0003580 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient SC medium C. albicans orf19.908 ORF FEN12 CAL0003580 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient SLAD medium C. albicans orf19.908 ORF FEN12 CAL0003580 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 invasive growth: decreased solid SLAD media C. albicans orf19.909 ORF STP4 CAL0003582 PMID: 17555439|CGD_REF: CAL0117968 homozygous diploid, classical genetics null Not recorded survival rate in stationary phase: decreased C. albicans orf19.909 ORF STP4 CAL0003582 PMID: 20041210|CGD_REF: CAL0124764 homozygous diploid, systematic mutation set null SN152 resistance to chemicals: decreased sodium dodecyl sulfate strongly sensitive C. albicans orf19.909 ORF STP4 CAL0003582 PMID: 15964282|CGD_REF: CAL0114274 homozygous diploid, systematic mutation set (split-marker transposon insertion strategy to disrupt both alleles) null BWP17 biofilm formation: normal C. albicans orf19.909 ORF STP4 CAL0003582 PMID: 20041210|CGD_REF: CAL0124764 homozygous diploid, systematic mutation set null SN152 invasive growth: increased YEPD medium at 30 deg C strongly increased C. albicans orf19.909 ORF STP4 CAL0003582 PMID: 22581526|CGD_REF: CAL0000157314 homozygous diploid, systematic mutation set null BWP17 resistance to chemicals: decreased caspofungin C. albicans orf19.909 ORF STP4 CAL0003582 PMID: 15964282|CGD_REF: CAL0114274 homozygous diploid, systematic mutation set (split-marker transposon insertion strategy to disrupt both alleles) null BWP17 viable C. albicans orf19.910 ORF PRP3 CAL0003600 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.916 ORF CAL0003605 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.920 ORF RMT2 CAL0003625 PMID: 17483287|CGD_REF: CAL0118089 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.921 ORF HMS1 CAL0003626 PMID: 20041210|CGD_REF: CAL0124764 homozygous diploid, systematic mutation set null SN152 colony appearance: abnormal YEPD medium at 37 or 42 deg C strongly decreased colony fuzziness and/or peripheral filamentation C. albicans orf19.921 ORF HMS1 CAL0003626 PMID: 22365851|CGD_REF: CAL0000144076 homozygous diploid, classical genetics null hms1::FRT/hms1::FRT SN95 virulence: decreased insect infection (G. mellonella model) C. albicans orf19.921 ORF HMS1 CAL0003626 PMID: 22365851|CGD_REF: CAL0000144076 homozygous diploid, classical genetics null hms1::FRT/hms1::FRT SN95 colony appearance: abnormal required for wrinkly colony morphology at elevated temperature C. albicans orf19.921 ORF HMS1 CAL0003626 PMID: 22365851|CGD_REF: CAL0000144076 homozygous diploid, classical genetics null hms1::FRT/hms1::FRT SN95 filamentous growth: absent mutant is unable to filament in response to 42 degree C temperature or to geldanamycin, a Hsp90p inhibitor that induces filamentous growth C. albicans orf19.921 ORF HMS1 CAL0003626 PMID: 23526879|CGD_REF: CAL0000158852 homozygous diploid, classical genetics null SN152 viable C. albicans orf19.921 ORF HMS1 CAL0003626 PMID: 23526879|CGD_REF: CAL0000158852 homozygous diploid, classical genetics null SN152 virulence: decreased significant defect in GI tract colonization mouse gastrointestinal tract infection C. albicans orf19.921 ORF HMS1 CAL0003626 PMID: 23526879|CGD_REF: CAL0000158852 homozygous diploid, classical genetics null SN152 virulence: decreased mouse intravenous infection C. albicans orf19.922 ORF ERG11 CAL0003627 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, competitive growth (haploinsufficient phenotype assay, barcode deletion set) null SC5314 resistance to chemicals: decreased fluconazole C. albicans orf19.922 ORF ERG11 CAL0003627 PMID: 16276890|CGD_REF: CAL0114983 heterozygous diploid, classical genetics reduction of function erg11-H310D Not recorded resistance to chemicals: increased fluconazole C. albicans orf19.922 ORF ERG11 CAL0003627 PMID: 15105135|CGD_REF: CAL0080962 unknown ploidy, classical genetics unspecified Other C. albicans resistance to chemicals: decreased 4-nitroquinoline N-oxide C. albicans orf19.922 ORF ERG11 CAL0003627 PMID: 15105135|CGD_REF: CAL0080962 unknown ploidy, classical genetics unspecified Other C. albicans resistance to chemicals: decreased terbinafine|1,10-phenanthroline|4-nitroquinoline N-oxide C. albicans orf19.922 ORF ERG11 CAL0003627 PMID: 15105135|CGD_REF: CAL0080962 unknown ploidy, classical genetics unspecified Other C. albicans resistance to chemicals: decreased fluconazole|itraconazole|ketoconazole C. albicans orf19.922 ORF ERG11 CAL0003627 PMID: 9527767|CGD_REF: CAL0081233 unknown ploidy, classical genetics unspecified Other C. albicans resistance to chemicals: increased fluconazole|itraconazole|ketoconazole C. albicans orf19.922 ORF ERG11 CAL0003627 PMID: 1880679|CGD_REF: CAL0091443 unknown ploidy, classical genetics unspecified Other C. albicans utilization of carbon source: absent succinic acid C. albicans orf19.922 ORF ERG11 CAL0003627 PMID: 9869573|CGD_REF: CAL0103701 unknown ploidy, classical genetics unspecified Other C. albicans resistance to chemicals: decreased acetate mutant shows increased sensitivity to carboxylates acetate, propionate, and benzoate (sodium acetate, not sodium chloride) C. albicans orf19.922 ORF ERG11 CAL0003627 PMID: 14657086|CGD_REF: CAL0080955 unknown ploidy, classical genetics unspecified Other C. albicans resistance to chemicals: increased triazoles multiple point mutations associated with azole resistance in clinical isolates C. albicans orf19.922 ORF ERG11 CAL0003627 PMID: 15611610|CGD_REF: CAL0082489 unknown ploidy, classical genetics unspecified Other C. albicans resistance to chemicals: increased fluconazole Y132H and G448V mutations found in a fluconazole-resistant clinical isolate C. albicans orf19.922 ORF ERG11 CAL0003627 PMID: 15552648|CGD_REF: CAL0082139 homozygous diploid, classical genetics null BWP17 viable fluconazole C. albicans orf19.922 ORF ERG11 CAL0003627 PMID: 15552648|CGD_REF: CAL0082139 homozygous diploid, classical genetics null BWP17 viable C. albicans orf19.922 ORF ERG11 CAL0003627 PMID: 12878497|CGD_REF: CAL0081252 homozygous diploid, classical genetics null Other C. albicans viable C. albicans orf19.922 ORF ERG11 CAL0003627 PMID: 12878497|CGD_REF: CAL0081252 homozygous diploid, classical genetics null Other C. albicans resistance to chemicals: increased amphotericin B C. albicans orf19.922 ORF ERG11 CAL0003627 PMID: 12878497|CGD_REF: CAL0081252 homozygous diploid, classical genetics null Other C. albicans resistance to chemicals: increased fluconazole C. albicans orf19.922 ORF ERG11 CAL0003627 PMID: 10537192|CGD_REF: CAL0081112 heterozygous diploid, classical genetics unspecified Other C. albicans resistance to chemicals: abnormal triazoles C. albicans orf19.922 ORF ERG11 CAL0003627 PMID: 15034753|CGD_REF: CAL0081253 heterozygous diploid, classical genetics overexpression SC5314 resistance to chemicals: increased fluconazole C. albicans orf19.922 ORF ERG11 CAL0003627 PMID: 15155210|CGD_REF: CAL0080657 heterozygous diploid, classical genetics unspecified Other C. albicans resistance to chemicals: increased triazoles single and multiple point mutations found in clinical isolates confer resistance to azole drugs C. albicans orf19.922 ORF ERG11 CAL0003627 PMID: 18363649|CGD_REF: CAL0118932 aneuploid, classical genetics overexpression Other C. albicans resistance to chemicals: increased fluconazole increased fluconazole resistance in aneuploid strains with multiplied copies of ERG11 C. albicans orf19.922 ORF ERG11 CAL0003627 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.922 ORF ERG11 CAL0003627 PMID: 20494978|CGD_REF: CAL0125636 heterozygous diploid, classical genetics null BWP17 resistance to chemicals: decreased clotrimazole (75 uM) growth in liquid culture confirmation of mutant phenotypes for heterozygous transposon insertion strains showing sensitivity in a large-scale assay C. albicans orf19.922 ORF ERG11 CAL0003627 PMID: 21135205|CGD_REF: CAL0139967 heterozygous diploid, large-scale survey (large-scale identification of genes essential for virulence in mouse) repressible CAI-4 virulence: absent mouse intravenous infection C. albicans orf19.923 ORF THR1 CAL0003628 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.923 ORF THR1 CAL0003628 PMID: 20305003|CGD_REF: CAL0125133 homozygous diploid, classical genetics null thr1::SAT1 SC5314 viable C. albicans orf19.923 ORF THR1 CAL0003628 PMID: 20305003|CGD_REF: CAL0125133 homozygous diploid, classical genetics null thr1::SAT1 SC5314 virulence: decreased mouse intravenous infection C. albicans orf19.923 ORF THR1 CAL0003628 PMID: 20305002|CGD_REF: CAL0125134 homozygous diploid, classical genetics null thr1::SAT1 SC5314 resistance to chemicals: decreased homoserine C. albicans orf19.925 ORF SAM51 CAL0003630 PMID: 23151513|CGD_REF: CAL0000158127 homozygous diploid, classical genetics null BWP17 viable C. albicans orf19.925 ORF SAM51 CAL0003630 PMID: 23151513|CGD_REF: CAL0000158127 homozygous diploid, classical genetics null BWP17 mitochondrial transport: decreased C. albicans orf19.926 ORF EXO1 CAL0003631 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.926 ORF EXO1 CAL0003631 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 invasive growth: decreased solid SLAD media C. albicans orf19.93 ORF CAL0000705 PMID: 17645752|CGD_REF: CAL0119305 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.93 ORF CAL0000705 PMID: 17645752|CGD_REF: CAL0119305 homozygous diploid, classical genetics null Not recorded virulence: decreased reconstituted human epithelium decreased capacity to cause tissue damage ex vivo model of infection C. albicans orf19.930 ORF PET9 CAL0003655 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.931 ORF CAL0003656 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: abnormal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.931 ORF CAL0003656 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: decreased rate liquid synthetic complete medium C. albicans orf19.931 ORF CAL0003656 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.931 ORF CAL0003656 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.933 ORF CAL0003658 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.936 ORF CAL0003661 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.936 ORF CAL0003661 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: decreased rate liquid synthetic complete medium C. albicans orf19.936 ORF CAL0003661 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.936 ORF CAL0003661 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.939 ORF NAM7 CAL0003666 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.939 ORF NAM7 CAL0003666 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 invasive growth: decreased solid SLAD media C. albicans orf19.940 ORF BUD2 CAL0003684 PMID: 16002653|CGD_REF: CAL0114400 homozygous diploid, classical genetics null BWP17 filamentous growth: increased increased branching frequency C. albicans orf19.940 ORF BUD2 CAL0003684 PMID: 16002653|CGD_REF: CAL0114400 homozygous diploid, classical genetics null BWP17 filamentous growth: abnormal solid milk-Tween, embedded in agar, solid or liquid serum media pseudohyphal growth under conditions that support wild-type hyphal growth; hyphal branching from random positions along hyphal cell, whereas wild-type branching initiates near a septum C. albicans orf19.940 ORF BUD2 CAL0003684 PMID: 16002653|CGD_REF: CAL0114400 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased Calcofluor White C. albicans orf19.940 ORF BUD2 CAL0003684 PMID: 16002653|CGD_REF: CAL0114400 heterozygous diploid, classical genetics null Not recorded heat sensitivity: normal reintegrant C. albicans orf19.940 ORF BUD2 CAL0003684 PMID: 16002653|CGD_REF: CAL0114400 homozygous diploid, classical genetics null Not recorded heat sensitivity: increased C. albicans orf19.940 ORF BUD2 CAL0003684 PMID: 16002653|CGD_REF: CAL0114400 homozygous diploid, classical genetics null Not recorded actin cytoskeleton morphology: abnormal yeast-form cells exhibit an increased number of actin patches and some have aberrant morphology; hyphae exhibit delocalized actin patches and randomly oriented actin cables C. albicans orf19.940 ORF BUD2 CAL0003684 PMID: 16002653|CGD_REF: CAL0114400 homozygous diploid, classical genetics null Not recorded budding pattern: abnormal bud site selection is more random than in wild type C. albicans orf19.940 ORF BUD2 CAL0003684 PMID: 18281602|CGD_REF: CAL0118849 homozygous diploid, classical genetics null BWP17 hyphal growth: abnormal decreased hyphal reorientation in response to ridges on substrate or electric field, decreased hyphal penetration into epithelial cells C. albicans orf19.940 ORF BUD2 CAL0003684 PMID: 16002653|CGD_REF: CAL0114400 heterozygous diploid, classical genetics null BWP17 hyphal growth: normal reintegrant C. albicans orf19.940 ORF BUD2 CAL0003684 PMID: 18281602|CGD_REF: CAL0118849 homozygous diploid, classical genetics null Not recorded interaction with host/environment: abnormal decrease in thigmotropic hyphal reorientation in response to ridges on substrate and in galvanotropic response to electric field C. albicans orf19.940 ORF BUD2 CAL0003684 PMID: 18281602|CGD_REF: CAL0118849 homozygous diploid, classical genetics null Not recorded interaction with host/environment: abnormal galvanotropic germ tube emergence orientation response and hyphal growth reorientation response do not occur C. albicans orf19.940 ORF BUD2 CAL0003684 PMID: 16002653|CGD_REF: CAL0114400 homozygous diploid, classical genetics null Not recorded cell size: increased cells are round and enlarged C. albicans orf19.940 ORF BUD2 CAL0003684 PMID: 21407800|CGD_REF: CAL0141800 homozygous diploid, classical genetics null BWP17 interaction with host/environment: abnormal significantly reduced adhesion and damage to epithelial cells, but normal invasion ex vivo model of infection C. albicans orf19.940 ORF BUD2 CAL0003684 PMID: 16002653|CGD_REF: CAL0114400 heterozygous diploid, classical genetics null Not recorded viable C. albicans orf19.940 ORF BUD2 CAL0003684 PMID: 16002653|CGD_REF: CAL0114400 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.940 ORF BUD2 CAL0003684 PMID: 18281602|CGD_REF: CAL0118849 homozygous diploid, classical genetics null Not recorded virulence: decreased cultured oral epithelial cells decreased hyphal penetration and capacity to damage cells in vitro model of infection C. albicans orf19.941 ORF SEC14 CAL0003685 PMID: 8896277|CGD_REF: CAL0081905 heterozygous diploid, classical genetics null Not recorded protein secretion: normal exoglucanase and acid phosphatase C. albicans orf19.941 ORF SEC14 CAL0003685 PMID: 14507372|CGD_REF: CAL0088818 heterozygous diploid, large-scale survey (large-scale identification of essential genes by gene replacement and conditional expression (GRACE) method) repressible CAI-4 inviable one allele is deleted and the other is placed under repressible Tet promoter C. albicans orf19.941 ORF SEC14 CAL0003685 PMID: 8896277|CGD_REF: CAL0081905 homozygous diploid, classical genetics null Not recorded inviable homozygous null mutant strain could not be recovered, suggesting that the gene is essential under the selection conditions C. albicans orf19.941 ORF SEC14 CAL0003685 PMID: 9387231|CGD_REF: CAL0081907 homozygous diploid, classical genetics null Not recorded inviable homozygous null mutant strain could not be recovered, suggesting that the gene is essential under the selection conditions C. albicans orf19.941 ORF SEC14 CAL0003685 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.941 ORF SEC14 CAL0003685 PMID: 8896277|CGD_REF: CAL0081905 heterozygous diploid, classical genetics null Not recorded viable wild-type growth rate C. albicans orf19.941 ORF SEC14 CAL0003685 PMID: 9387231|CGD_REF: CAL0081907 heterozygous diploid, classical genetics null Not recorded viable C. albicans orf19.941 ORF SEC14 CAL0003685 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient SC medium C. albicans orf19.942 ORF KRE62 CAL0003686 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.942 ORF KRE62 CAL0003686 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.942 ORF KRE62 CAL0003686 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.942 ORF KRE62 CAL0003686 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.942 ORF KRE62 CAL0003686 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.942 ORF KRE62 CAL0003686 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 invasive growth: decreased solid SLAD media C. albicans orf19.943 ORF FET33 CAL0003687 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.943 ORF FET33 CAL0003687 PMID: 23579686|CGD_REF: CAL0000158899 homozygous diploid, classical genetics null fet33::ARG4/fet33::URA3-dpl200 BWP17 viable C. albicans orf19.943 ORF FET33 CAL0003687 PMID: 23579686|CGD_REF: CAL0000158899 homozygous diploid, classical genetics null fet33::ARG4/fet33::URA3-dpl200 BWP17 chemical compound accumulation: decreased cellular iron iron limiting conditions no obvious growth defect in iron-limited medium C. albicans orf19.943 ORF FET33 CAL0003687 PMID: 23579686|CGD_REF: CAL0000158899 homozygous diploid, classical genetics null fet33::ARG4/fet33::URA3-dpl200 BWP17 virulence: normal mouse intravenous infection C. albicans orf19.945 ORF VPS2 CAL0003689 PMID: 15371534|CGD_REF: CAL0082134 homozygous diploid, classical genetics null BWP17 hyphal growth: normal solid medium, alkaline pH C. albicans orf19.945 ORF VPS2 CAL0003689 PMID: 18466294|CGD_REF: CAL0119004 homozygous diploid, classical genetics null Not recorded utilization of iron source: absent hemoglobin C. albicans orf19.945 ORF VPS2 CAL0003689 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.945 ORF VPS2 CAL0003689 PMID: 15371534|CGD_REF: CAL0082134 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.946 ORF MET14 CAL0003690 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.949 ORF CAL0003695 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.949 ORF CAL0003695 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient YPD medium C. albicans orf19.949 ORF CAL0003695 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient SC medium C. albicans orf19.949 ORF CAL0003695 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient YNB medium C. albicans orf19.95 ORF CAL0000707 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.95 ORF CAL0000707 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.95 ORF CAL0000707 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.95 ORF CAL0000707 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.952 ORF CAL0003713 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 invasive growth: decreased solid SLAD media C. albicans orf19.954 ORF CAL0003714 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.96 ORF TOP1 CAL0000708 PMID: 9043115|CGD_REF: CAL0081977 heterozygous diploid, classical genetics repressible Not recorded germ tube formation: decreased C. albicans orf19.96 ORF TOP1 CAL0000708 PMID: 9043115|CGD_REF: CAL0081977 heterozygous diploid, classical genetics repressible Not recorded vegetative growth: decreased rate C. albicans orf19.96 ORF TOP1 CAL0000708 PMID: 9043115|CGD_REF: CAL0081977 heterozygous diploid, classical genetics repressible Not recorded cellular morphology: abnormal C. albicans orf19.96 ORF TOP1 CAL0000708 PMID: 9043115|CGD_REF: CAL0081977 heterozygous diploid, classical genetics null Not recorded viable C. albicans orf19.96 ORF TOP1 CAL0000708 PMID: 9043115|CGD_REF: CAL0081977 heterozygous diploid, classical genetics repressible Not recorded virulence: decreased mouse intravenous infection C. albicans orf19.962 ORF CAL0003742 PMID: 20494978|CGD_REF: CAL0125636 heterozygous diploid, classical genetics null BWP17 resistance to chemicals: decreased clotrimazole (75 uM) growth in liquid culture confirmation of mutant phenotypes for heterozygous transposon insertion strains showing sensitivity in a large-scale assay C. albicans orf19.964 ORF SMC4 CAL0003745 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.967 ORF CAL0003747 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.967 ORF CAL0003747 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient SLAD medium C. albicans orf19.969 ORF CAL0003751 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.97 ORF CAN1 CAL0000709 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.971 ORF SKN7 CAL0003772 PMID: 15039366|CGD_REF: CAL0081919 homozygous diploid, classical genetics null CAI-4 hyphal growth: absent 10% serum, M-199 pH 7.5, and Spider media C. albicans orf19.971 ORF SKN7 CAL0003772 PMID: 15039366|CGD_REF: CAL0081919 homozygous diploid, classical genetics null Not recorded oxidative stress resistance: decreased hydrogen peroxide C. albicans orf19.971 ORF SKN7 CAL0003772 PMID: 20041210|CGD_REF: CAL0124764 homozygous diploid, systematic mutation set null SN152 oxidative stress resistance: decreased hydrogen peroxide strongly sensitive C. albicans orf19.971 ORF SKN7 CAL0003772 PMID: 15039366|CGD_REF: CAL0081919 homozygous diploid, classical genetics null Not recorded oxidative stress resistance: decreased tert-butyl hydroperoxide C. albicans orf19.971 ORF SKN7 CAL0003772 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.971 ORF SKN7 CAL0003772 PMID: 15039366|CGD_REF: CAL0081919 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.971 ORF SKN7 CAL0003772 PMID: 15039366|CGD_REF: CAL0081919 homozygous diploid, classical genetics null Not recorded virulence: decreased slight decrease mouse intravenous infection C. albicans orf19.972 ORF CAL0003774 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.974 ORF ROT2 CAL0003777 PMID: 17933909|CGD_REF: CAL0118852 homozygous diploid, classical genetics null CAI-4 filamentous growth: absent solid Spider medium C. albicans orf19.974 ORF ROT2 CAL0003777 PMID: 17933909|CGD_REF: CAL0118852 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased Hygromycin B C. albicans orf19.974 ORF ROT2 CAL0003777 PMID: 17933909|CGD_REF: CAL0118852 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased tunicamycin C. albicans orf19.974 ORF ROT2 CAL0003777 PMID: 17933909|CGD_REF: CAL0118852 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased Calcofluor White C. albicans orf19.974 ORF ROT2 CAL0003777 PMID: 17933909|CGD_REF: CAL0118852 homozygous diploid, classical genetics null Not recorded vegetative growth: decreased rate rich medium at 30 deg C C. albicans orf19.974 ORF ROT2 CAL0003777 PMID: 17933909|CGD_REF: CAL0118852 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased sodium dodecyl sulfate C. albicans orf19.974 ORF ROT2 CAL0003777 PMID: 17933909|CGD_REF: CAL0118852 homozygous diploid, classical genetics null Not recorded cell size: increased C. albicans orf19.974 ORF ROT2 CAL0003777 PMID: 17933909|CGD_REF: CAL0118852 homozygous diploid, classical genetics null Not recorded chemical compound accumulation: decreased mannan decreased cell wall mannan C. albicans orf19.974 ORF ROT2 CAL0003777 PMID: 17933909|CGD_REF: CAL0118852 homozygous diploid, classical genetics null Not recorded resistance to chemicals: decreased Congo Red C. albicans orf19.974 ORF ROT2 CAL0003777 PMID: 17933909|CGD_REF: CAL0118852 homozygous diploid, classical genetics null Not recorded chemical compound accumulation: decreased glucan decreased cell wall glucan C. albicans orf19.974 ORF ROT2 CAL0003777 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.974 ORF ROT2 CAL0003777 PMID: 17933909|CGD_REF: CAL0118852 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.974 ORF ROT2 CAL0003777 PMID: 17933909|CGD_REF: CAL0118852 homozygous diploid, classical genetics null Not recorded virulence: decreased mouse intravenous infection C. albicans orf19.976 ORF BRE1 CAL0003779 PMID: 12773383|CGD_REF: CAL0087974 heterozygous diploid, classical genetics (haploinsufficient phenotype assay) null CAI-4 filamentous growth: increased solid Spider medium heterozygous transposon insertion C. albicans orf19.976 ORF BRE1 CAL0003779 PMID: 15964282|CGD_REF: CAL0114274 homozygous diploid, systematic mutation set (split-marker transposon insertion strategy to disrupt both alleles) null BWP17 inviable homozygous null mutant strain could not be recovered, suggesting that the gene is essential under the selection conditions C. albicans orf19.976 ORF BRE1 CAL0003779 PMID: 12773383|CGD_REF: CAL0087974 heterozygous diploid, classical genetics (haploinsufficient phenotype assay) null CAI-4 viable heterozygous transposon insertion C. albicans orf19.976 ORF BRE1 CAL0003779 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.978 ORF BDF1 CAL0003781 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.978 ORF BDF1 CAL0003781 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient YPD medium C. albicans orf19.979 ORF FAS1 CAL0003782 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, competitive growth (haploinsufficient phenotype assay, barcode deletion set) null SC5314 resistance to chemicals: decreased cerulenin C. albicans orf19.979 ORF FAS1 CAL0003782 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, competitive growth (haploinsufficient phenotype assay, barcode deletion set) null SC5314 vegetative growth: decreased rate modest effect C. albicans orf19.979 ORF FAS1 CAL0003782 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.979 ORF FAS1 CAL0003782 PMID: 21135205|CGD_REF: CAL0139967 heterozygous diploid, large-scale survey (large-scale identification of genes essential for virulence in mouse) repressible CAI-4 virulence: absent mouse intravenous infection C. albicans orf19.984 ORF PHO8 CAL0003811 PMID: 19555456|CGD_REF: CAL0123821 homozygous diploid, classical genetics null Not recorded viable C. albicans orf19.986 ORF GLY1 CAL0003813 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.986 ORF GLY1 CAL0003813 PMID: 14507372|CGD_REF: CAL0088818 heterozygous diploid, large-scale survey (large-scale identification of essential genes by gene replacement and conditional expression (GRACE) method) repressible CAI-4 viable one allele is deleted and the other is placed under repressible Tet promoter C. albicans orf19.986 ORF GLY1 CAL0003813 PMID: 10641038|CGD_REF: CAL0081354 homozygous diploid, classical genetics null Other C. albicans viable wild-type growth rate C. albicans orf19.988 ORF CAL0003815 PMID: 22438810|CGD_REF: CAL0000156986 homozygous diploid, classical genetics null BWP17 viable C. albicans orf19.988 ORF CAL0003815 PMID: 22438810|CGD_REF: CAL0000156986 homozygous diploid, classical genetics null BWP17 virulence: decreased mutants have reduced capacity to damage oral epithelial cells in vitro model of infection (monolayers of oral epithelial cells) C. albicans orf19.988 ORF CAL0003815 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.989 ORF CAL0003817 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.99 ORF HAL21 CAL0000710 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.991 ORF DJP1 CAL0003840 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.992 ORF LKH1 CAL0003842 PMID: 17604452|CGD_REF: CAL0118249 heterozygous diploid, large-scale survey (haploinsufficient phenotype assay, barcode deletion set) null SC5314 viable C. albicans orf19.992 ORF LKH1 CAL0003842 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient YPD medium C. albicans orf19.992 ORF LKH1 CAL0003842 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient YNB medium C. albicans orf19.992 ORF LKH1 CAL0003842 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 haploinsufficient SLAD medium C. albicans orf19.993 ORF CAL0003844 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.993 ORF CAL0003844 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: decreased rate liquid synthetic complete medium C. albicans orf19.993 ORF CAL0003844 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.993 ORF CAL0003844 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.996 ORF CAL0003847 PMID: 20949076|CGD_REF: CAL0126511 heterozygous diploid, competitive growth null BWP17 invasive growth: decreased solid SLAD media C. albicans orf19.998 ORF CAL0003850 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, competitive growth (competitive growth in the mouse host using null mutant set generated with virulence-neutral markers) null SN152 competitive fitness: normal growth in BALB/c mouse host R\I score is the median log2(R/I) value representing abundance of the mutant in recovered pool relative to inoculum mouse intravenous infection C. albicans orf19.998 ORF CAL0003850 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 colony appearance: normal solid Spider medium Morphology (M) score represents relative sizes of central and peripheral regions of colony C. albicans orf19.998 ORF CAL0003850 PMID: 14663094|CGD_REF: CAL0080633 homozygous diploid, systematic mutation set (homozygous insertion mutants generated with URA3-ARG4-URA3 (UAU1) cassette) null BWP17 viable C. albicans orf19.998 ORF CAL0003850 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 vegetative growth: normal rate liquid synthetic complete medium C. albicans orf19.998 ORF CAL0003850 PMID: 20543849|CGD_REF: CAL0125565 homozygous diploid, systematic mutation set null SN152 viable C. albicans orf19.999 ORF GCA2 CAL0003852 PMID: 19529758|CGD_REF: CAL0123764 heterozygous diploid, classical genetics overexpression BWP17 biofilm formation: abnormal C. albicans