ARG100 ARG100 CAF0006874 Unknown/unspecified Arginine auxotrophy PMID:8194754 FGR21 FGR21 CAF0006879 Unknown/unspecified Filamentous growth abnormal Decreased filamentous growth (solid Spider medium); transposon is proximal to, but not within, the ORF PMID:12773383 FGR36 FGR36 CAF0006880 Heterozygous null Filamentous growth abnormal Decreased filamentous growth (solid Spider medium); heterozygous transposon mutant allele PMID:12773383 FGR36 FGR36 CAF0006880 Heterozygous null Viable Heterozygous transposon mutant allele PMID:12773383 FGR45 FGR45 CAF0006881 Unknown/unspecified Filamentous growth abnormal Decreased filamentous growth (solid Spider medium), increased filamentous growth (solid YEPD + serum); transposon is proximal to, but not within, the ORF PMID:12773383 FGR49 FGR49 CAF0006882 Heterozygous null Filamentous growth abnormal Increased filamentous growth (solid YEPD + serum); heterozygous transposon mutant allele PMID:12773383 FGR49 FGR49 CAF0006882 Heterozygous null Viable Heterozygous transposon mutant allele PMID:12773383 LET1 LET1 CAL0006585 Homozygous null Inviable PMID:6757662 LET1 LET1 CAL0006585 Heterozygous null Viable PMID:6757662 LET2 LET2 CAL0006586 Homozygous null Inviable PMID:6757662 LET2 LET2 CAL0006586 Heterozygous null Viable PMID:6757662 MET MET CAL0006602 Homozygous null Methionine auxotrophy PMID:6757662 MTLalpha2 MTLALPHA2 CAL0006612 Misexpression Virulence defect Expression in an MTLa/MTLa background causes increased virulence (mouse intravenous infection) PMID:15695357 MTLalpha2 MTLALPHA2 CAL0006612 Homozygous null Viable Genetic interaction experiments demonstrate that Alpha1p is required for alpha mating type, A1p is required for the a mating type, and both Alpha2p and A1p are required to repress the white-opaque switch that precedes mating. PMID:14622594 MTLalpha2 MTLALPHA2 CAL0006612 Homozygous null Transcription regulation abnormal PMID:14622594 MTLalpha2 MTLALPHA2 CAL0006612 Homozygous null Phenotypic switching abnormal Mutants lacking A1p or Alpha2p show a defect in wild-type repression of white-opaque switching; mutants undergo switching, whereas wild-type cells that contain A1p and Alpha2p do not. PMID:14622594 MTLalpha2 MTLALPHA2 CAL0006612 Homozygous null Viable gene deleted from a/alpha heterozygous strain PMID:17555440 MTLalpha2 MTLALPHA2 CAL0006612 Homozygous null Virulence defect Decreased virulence (murine intravenous infection); variability observed among strain backgrounds; gene deleted from a/alpha heterozygous strain PMID:17555440 TER1 CAF0007465 Homozygous null Viable PMID:17609387 TER1 CAF0007465 Homozygous null abolished telomerase activity PMID:17609387 TER1 CAF0007465 Homozygous null Telomere shortening PMID:17609387 orf19.10 ALK8 CAL0000502 Homozygous null Viable PMID:11536334 orf19.10 ALK8 CAL0000502 Homozygous null Wild-type drug sensitivity PMID:11536334 orf19.10 ALK8 CAL0000502 Homozygous null Slow growth Slow growth during utilization of alkanes as the carbon source PMID:11536334 orf19.10 ALK8 CAL0000502 Overexpression Drug susceptibility altered Resistance to fluconazole PMID:11536334 orf19.10 ALK8 CAL0000502 Depletion Viable large-scale identification of essential genes by gene replacement and conditional expression (GRACE) method PMID:14507372 orf19.10 ALK8 CAL0000502 Heterozygous null Viable Barcode deletion set, fitness test (haploinsufficient phenotype assay) PMID:17604452 orf19.1005 CAL0001021 Homozygous null Viable PMID:14663094 orf19.1006 CAL0001023 Heterozygous null Filamentous growth abnormal Increased filamentous growth or striated appearance of colony (solid YEPD + serum); heterozygous deletion or transposon allele PMID:12773383 orf19.1006 CAL0001023 Heterozygous null Viable Heterozygous deletion allele, heterozygous transposon mutant allele PMID:12773383 orf19.1007 CAL0001024 Homozygous null Viable Insertion mutation, supplementary data PMID:15964282 orf19.1007 CAL0001024 Homozygous null Wild-type biofilm formation Insertion mutation, supplementary data PMID:15964282 orf19.1007 CAL0001024 Heterozygous null Viable Barcode deletion set, fitness test (haploinsufficient phenotype assay) PMID:17604452 orf19.1011 CAL0001040 Heterozygous null Viable Barcode deletion set, fitness test (haploinsufficient phenotype assay) PMID:17604452 orf19.1012 CAL0001042 Heterozygous null Viable Barcode deletion set, fitness test (haploinsufficient phenotype assay) PMID:17604452 orf19.1026 CAL0001085 Heterozygous null Viable Barcode deletion set, fitness test (haploinsufficient phenotype assay) PMID:17604452 orf19.1027 PDR16 CAL0001086 Homozygous null Viable PMID:16796687 orf19.1027 PDR16 CAL0001086 Homozygous null Drug susceptibility altered increased sensitivity to fluconazole PMID:16796687 orf19.1027 PDR16 CAL0001086 Overexpression Drug susceptibility altered decreased sensitivity to fluconazole PMID:16796687 orf19.1029 CAL0001088 Heterozygous null Viable Barcode deletion set, fitness test (haploinsufficient phenotype assay) PMID:17604452 orf19.1031 HMG1 CAL0001113 Heterozygous null Viable Barcode deletion set, fitness test (haploinsufficient phenotype assay) PMID:17604452 orf19.1032 SKO1 CAL0001116 Homozygous null Viable No obvious phenotype PMID:11532939 orf19.1033 STR2 CAL0001118 Homozygous null Viable PMID:14663094 orf19.1033 STR2 CAL0001118 Heterozygous null Viable Barcode deletion set, fitness test (haploinsufficient phenotype assay) PMID:17604452 orf19.1035 WAR1 CAL0001122 Homozygous null increased sensitivity to weak organic acids PMID:16544288 orf19.1035 WAR1 CAL0001122 Homozygous null Viable PMID:16544288 orf19.1035 WAR1 CAL0001122 Overexpression decreased sensitivity to weak organic acids PMID:16544288 orf19.1035 WAR1 CAL0001122 Heterozygous null Viable Barcode deletion set, fitness test (haploinsufficient phenotype assay) PMID:17604452 orf19.1036 CAL0001124 Heterozygous null Viable Barcode deletion set, fitness test (haploinsufficient phenotype assay) PMID:17604452 orf19.1040 MAD2 CAL0001147 Heterozygous null Drug susceptibility altered Increased sensitivity to nocodazole PMID:12100546 orf19.1040 MAD2 CAL0001147 Homozygous null Drug susceptibility altered Increased sensitivity to nocodazole PMID:12100546 orf19.1040 MAD2 CAL0001147 Homozygous null Filamentous growth abnormal Abolished filament formation inside macrophages PMID:12100546 orf19.1040 MAD2 CAL0001147 Homozygous null increased mitotic chromosome loss PMID:12100546 orf19.1040 MAD2 CAL0001147 Homozygous null Oxidative stress susceptibility altered Increased sensitivity to hydrogen peroxide PMID:12100546 orf19.1040 MAD2 CAL0001147 Heterozygous null Viable PMID:12100546 orf19.1040 MAD2 CAL0001147 Homozygous null Viable PMID:12100546 orf19.1040 MAD2 CAL0001147 Homozygous null Virulence defect Sensitive to macrophage killing PMID:12100546 orf19.1040 MAD2 CAL0001147 Homozygous null Virulence defect Decreased kidney colonization (mouse model of systemic infection) PMID:12100546 orf19.1040 MAD2 CAL0001147 Homozygous null Virulence defect Greatly decreased virulence (mouse model of systemic infection) PMID:12100546 orf19.1040 MAD2 CAL0001147 Heterozygous null Viable Barcode deletion set, fitness test (haploinsufficient phenotype assay) PMID:17604452 orf19.1042 POR1 CAL0001151 Heterozygous null Viable Barcode deletion set, fitness test (haploinsufficient phenotype assay) PMID:17604452 orf19.1045 CAL0001156 Heterozygous null Viable Barcode deletion set, fitness test (haploinsufficient phenotype assay) PMID:17604452 orf19.1047 ERB1 CAL0001157 Heterozygous null Viable Barcode deletion set, fitness test (haploinsufficient phenotype assay) PMID:17604452 orf19.1048 IFD6 CAL0001158 Heterozygous null Viable Barcode deletion set, fitness test (haploinsufficient phenotype assay) PMID:17604452 orf19.105 HAL22 CAL0002967 Heterozygous null Viable Barcode deletion set, fitness test (haploinsufficient phenotype assay) PMID:17604452 orf19.1051 HTA2 CAL0001183 Heterozygous null Viable Barcode deletion set, fitness test (haploinsufficient phenotype assay) PMID:17604452 orf19.1055 CDC3 CAL0001190 Homozygous null (inferred) Inviable PMID:12181342 orf19.1055 CDC3 CAL0001190 Heterozygous null Viable Barcode deletion set, fitness test (haploinsufficient phenotype assay) PMID:17604452 orf19.1062 CAL0001205 Heterozygous null Viable Barcode deletion set, fitness test (haploinsufficient phenotype assay) PMID:17604452 orf19.1063 CAL0001206 Heterozygous null Viable Barcode deletion set, fitness test (haploinsufficient phenotype assay) PMID:17604452 orf19.1064 ACS2 CAL0001207 Heterozygous null Viable Barcode deletion set, fitness test (haploinsufficient phenotype assay) PMID:17604452 orf19.1065 SSA2 CAL0001208 Homozygous null Other stress susceptibility altered Somewhat increased resistance to human beta-defensin peptides (strain is also heterozygous for deletion of HSP70) PMID:16377704 orf19.1065 SSA2 CAL0001208 Homozygous null Viable PMID:16720580 orf19.1065 SSA2 CAL0001208 Homozygous null Other stress susceptibility altered decreased sensitivity to human salivary histatin 5 PMID:42021 orf19.1066 CAL0001209 Heterozygous null Viable Barcode deletion set, fitness test (haploinsufficient phenotype assay) PMID:17604452 orf19.1067 GPM2 CAL0001210 Heterozygous null Viable Barcode deletion set, fitness test (haploinsufficient phenotype assay) PMID:17604452 orf19.1069 RPN4 CAL0001212 Heterozygous null Viable Barcode deletion set, fitness test (haploinsufficient phenotype assay) PMID:17604452 orf19.107 CAL0002969 Heterozygous null Viable Barcode deletion set, fitness test (haploinsufficient phenotype assay) PMID:17604452 orf19.1070 CAL0001220 Heterozygous null Viable Barcode deletion set, fitness test (haploinsufficient phenotype assay) PMID:17604452 orf19.10712 MTLALPHA1 CAL0006611 Homozygous null Viable Genetic interaction experiments demonstrate that Alpha1p is required for alpha mating type, A1p is required for the a mating type, and both Alpha2p and A1p are required to repress the white-opaque switch that precedes mating. PMID:14622594 orf19.1077 ATM1 CAL0001228 Heterozygous null Viable Barcode deletion set, fitness test (haploinsufficient phenotype assay) PMID:17604452 orf19.1079 CAL0001230 Heterozygous null Viable Barcode deletion set, fitness test (haploinsufficient phenotype assay) PMID:17604452 orf19.1083 CAL0001251 Heterozygous null Viable Barcode deletion set, fitness test (haploinsufficient phenotype assay) PMID:17604452 orf19.1084 CDC39 CAL0001252 Heterozygous null Filamentous growth abnormal Decreased filamentous growth (solid YEPD + serum); heterozygous transposon mutant allele PMID:12773383 orf19.10841 POX18 CAL0006648 Homozygous null Viable PMID:14663094 orf19.1085 CAL0001253 Heterozygous null Viable Barcode deletion set, fitness test (haploinsufficient phenotype assay) PMID:17604452 orf19.109 CAL0002971 Heterozygous null Viable Barcode deletion set, fitness test (haploinsufficient phenotype assay) PMID:17604452 orf19.1093 FLO8 CAL0001280 Homozygous null Hyphal growth abnormal Abolished hyphal growth (yeast-form growth observed), liquid or solid serum media, solid Lee's medium (deletion of LUFS domain or entire gene) PMID:16267276 orf19.1093 FLO8 CAL0001280 Homozygous null Transcription regulation abnormal Abolished hyphal induction of hyphal-specific genes (deletion of LUFS domain or entire gene) PMID:16267276 orf19.1093 FLO8 CAL0001280 Heterozygous null Viable PMID:16267276 orf19.1093 FLO8 CAL0001280 Homozygous null Viable PMID:16267276 orf19.1093 FLO8 CAL0001280 Heterozygous null Hyphal growth abnormal Partial defect in hyphal growth PMID:16267276 orf19.1093 FLO8 CAL0001280 Heterozygous null Transcription regulation abnormal Decreased hyphal induction of hyphal-specific genes PMID:16267276 orf19.1093 FLO8 CAL0001280 Homozygous null Virulence defect Abolished virulence, mouse intravenous infection (complemented strain shows wild-type virulence) PMID:16267276 orf19.1093 FLO8 CAL0001280 Homozygous null Hyphal growth abnormal Hyperfilamentation; YPS agar-embedded growth at 25 deg (microaerophilic growth) PMID:16267276 orf19.1093 FLO8 CAL0001280 Heterozygous null Viable Barcode deletion set, fitness test (haploinsufficient phenotype assay) PMID:17604452 orf19.1097 ALS2 CAL0001283 Heterozygous null Viable PMID:15870470 orf19.1097 ALS2 CAL0001283 Homozygous null (inferred) Inviable Strain construction failed, possibly because mutant is inviable, but possibly for technical reasons PMID:15870470 orf19.1097 ALS2 CAL0001283 Overexpression Viable No obvious phenotype PMID:15870470 orf19.1097 ALS2 CAL0001283 Depletion Viable PMID:15870470 orf19.1097 ALS2 CAL0001283 Depletion Hyphal growth abnormal Decreased germ tube induction (liquid RPMI, Lee, or in reconstituted human epithelium) PMID:15870470 orf19.1097 ALS2 CAL0001283 Depletion Adhesion abnormal Decreased adhesion (vascular endothelial cells or reconstituted human epithelium, but not BEC) PMID:15870470 orf19.1097 ALS2 CAL0001283 Depletion Virulence defect Reconstituted human epithelium PMID:15870470 orf19.1097 ALS2 CAL0001283 Depletion Biofilm formation abnormal Decreased biofilm formation (catheter model in vitro) PMID:15870470 orf19.1097 ALS2 CAL0001283 Depletion Transcription regulation abnormal Increased transcription of PGA6 and (possibly compensatory) increase in ALS4 transcription PMID:15870470 orf19.1104 CAL0001852 Heterozygous null Viable Barcode deletion set, fitness test (haploinsufficient phenotype assay) PMID:17604452 orf19.1105.2 PGA56 CAL0006784 Homozygous null Viable Mutation made in context of Sou+ strain, which is monosomic for Chr. 5 PMID:16099828 orf19.1108 HAM1 CAL0001858 Heterozygous null Viable Barcode deletion set, fitness test (haploinsufficient phenotype assay) PMID:17604452 orf19.111 CAN2 CAL0002992 Heterozygous null Viable Barcode deletion set, fitness test (haploinsufficient phenotype assay) PMID:17604452 orf19.1110 CAL0001872 Heterozygous null Viable Barcode deletion set, fitness test (haploinsufficient phenotype assay) PMID:17604452 orf19.1111 CAL0001873 Heterozygous null Viable Barcode deletion set, fitness test (haploinsufficient phenotype assay) PMID:17604452 orf19.1112 BUD7 CAL0001875 Heterozygous null Viable Barcode deletion set, fitness test (haploinsufficient phenotype assay) PMID:17604452 orf19.1115 GUK1 CAL0001880 Heterozygous null Viable Barcode deletion set, fitness test (haploinsufficient phenotype assay) PMID:17604452 orf19.1119 MTR10 CAL0001884 Heterozygous null Viable Barcode deletion set, fitness test (haploinsufficient phenotype assay) PMID:17604452 orf19.1124 CAL0001920 Heterozygous null Viable Barcode deletion set, fitness test (haploinsufficient phenotype assay) PMID:17604452 orf19.113 CIP1 CAL0002993 Homozygous null Viable PMID:16339733 orf19.113 CIP1 CAL0002993 Homozygous null Oxidative stress susceptibility altered Increased sensitivity to hydrogen peroxide PMID:16339733 orf19.1130 CAL0001955 Heterozygous null Viable Barcode deletion set, fitness test (haploinsufficient phenotype assay) PMID:17604452 orf19.1135 CAS1 CAL0001964 Homozygous null Viable Insertion mutation, supplementary data PMID:15964282 orf19.1135 CAS1 CAL0001964 Homozygous null Wild-type biofilm formation Insertion mutation, supplementary data PMID:15964282 orf19.1135 CAS1 CAL0001964 Homozygous null Drug susceptibility altered Slight increase in caspofungin sensitivity PMID:16552442 orf19.1135 CAS1 CAL0001964 Homozygous null Viable PMID:16552442 orf19.1136 CAL0001966 Heterozygous null Viable Barcode deletion set, fitness test (haploinsufficient phenotype assay) PMID:17604452 orf19.1137 CAL0001967 Heterozygous null Viable Barcode deletion set, fitness test (haploinsufficient phenotype assay) PMID:17604452 orf19.1139 CAL0001968 Heterozygous null Viable Barcode deletion set, fitness test (haploinsufficient phenotype assay) PMID:17604452 orf19.1142 CAL0002003 Heterozygous null Viable Barcode deletion set, fitness test (haploinsufficient phenotype assay) PMID:17604452 orf19.11450 CAL0006785 Homozygous null Viable PMID:14663094 orf19.1152 CAL0002042 Heterozygous null Viable Barcode deletion set, fitness test (haploinsufficient phenotype assay) PMID:17604452 orf19.1153 GAD1 CAL0002044 Heterozygous null Viable Barcode deletion set, fitness test (haploinsufficient phenotype assay) PMID:17604452 orf19.1154 EGD1 CAL0002046 Heterozygous null Viable Barcode deletion set, fitness test (haploinsufficient phenotype assay) PMID:17604452 orf19.1155 DPP2 CAL0002048 Heterozygous null Viable Barcode deletion set, fitness test (haploinsufficient phenotype assay) PMID:17604452 orf19.1159 CAL0002052 Heterozygous null Viable Barcode deletion set, fitness test (haploinsufficient phenotype assay) PMID:17604452 orf19.1160 CAL0002067 Heterozygous null Viable Barcode deletion set, fitness test (haploinsufficient phenotype assay) PMID:17604452 orf19.1161 PLD1 CAL0002069 Homozygous null Viable PMID:11283284|PMID:15552646 orf19.1161 PLD1 CAL0002069 Homozygous null Virulence defect Decreased virulence and organ colonization in mouse oral or intravenous infection model, despite wild-type intestinal colonization; decreased tissue penetration under some, but not all, conditions PMID:15552646 orf19.1161 PLD1 CAL0002069 Homozygous null Hyphal growth abnormal Decreased hyphal growth (solid serum or Spider media), but wild-type hyphal growth in liquid media PMID:11283284 orf19.1161 PLD1 CAL0002069 Homozygous null Filamentous growth abnormal Decreased agar invasion PMID:11283284 orf19.1161 PLD1 CAL0002069 Homozygous null Hyphal growth abnormal Increased hyphal growth (solid cornmeal + Tween 80 [CMA/T] medium), abnormal hyphal morphology PMID:11283284 orf19.1161 PLD1 CAL0002069 Homozygous null Virulence defect Abolished virulence (oral infection of immunodeficient mice) PMID:11283284 orf19.1161 PLD1 CAL0002069 Homozygous null Wild-type virulence Wild-type virulence in a model of oral infection (reconstituted human epithelium) PMID:11283284 orf19.1161 PLD1 CAL0002069 Homozygous null Hyphal growth abnormal Increased inhibition of hyphal growth by propranolol PMID:12384374 orf19.1161 PLD1 CAL0002069 Homozygous null Drug susceptibility altered Increased inhibition of cell growth by propranolol PMID:12384374 orf19.1164 GAR1 CAL0002072 Heterozygous null Viable Barcode deletion set, fitness test (haploinsufficient phenotype assay) PMID:17604452 orf19.1166 CTA3 CAL0002073 Homozygous null Viable PMID:17431925 orf19.1166 CTA3 CAL0002073 Homozygous null Wild-type cell morphology no defects in polarized growth detected PMID:17431925 orf19.1166 CTA3 CAL0002073 Heterozygous null Viable Barcode deletion set, fitness test (haploinsufficient phenotype assay) PMID:17604452 orf19.1167 CAL0002074 Heterozygous null Viable Barcode deletion set, fitness test (haploinsufficient phenotype assay) PMID:17604452 orf19.117 CAL0002999 Heterozygous null Viable Barcode deletion set, fitness test (haploinsufficient phenotype assay) PMID:17604452 orf19.1170 ARO7 CAL0002091 Heterozygous null Viable Barcode deletion set, fitness test (haploinsufficient phenotype assay) PMID:17604452 orf19.1171 CAL0002093 Heterozygous null Viable Barcode deletion set, fitness test (haploinsufficient phenotype assay) PMID:17604452 orf19.1178 CAL0002100 Homozygous null Viable Insertion mutation, supplementary data PMID:15964282 orf19.1178 CAL0002100 Homozygous null Wild-type biofilm formation Insertion mutation, supplementary data PMID:15964282 orf19.118 FAD2 CAL0003001 Homozygous null Viable PMID:16622072 orf19.118 FAD2 CAL0003001 Homozygous null abnormal polyunsaturated fatty acid composition PMID:16622072 orf19.118 FAD2 CAL0003001 Heterozygous null Viable Barcode deletion set, fitness test (haploinsufficient phenotype assay) PMID:17604452 orf19.1180 CAL0002124 Heterozygous null Viable Barcode deletion set, fitness test (haploinsufficient phenotype assay) PMID:17604452 orf19.1185 CAL0002130 Heterozygous null Viable Barcode deletion set, fitness test (haploinsufficient phenotype assay) PMID:17604452 orf19.1187 CPH2 CAL0002132 Overexpression Cell morphology abnormal Elongated cells PMID:11533231 orf19.1187 CPH2 CAL0002132 Homozygous null Hyphal growth abnormal Decreased hyphal growth (growth condition-specific) PMID:11533231 orf19.1187 CPH2 CAL0002132 Homozygous null Hyphal growth abnormal Decreased hyphal growth (liquid Lee's + various carbon sources) PMID:11533231 orf19.1187 CPH2 CAL0002132 Homozygous null Hyphal growth abnormal Decreased hyphal growth (solid SSA, solid Lee's, solid media + serum) PMID:11533231 orf19.1187 CPH2 CAL0002132 Homozygous null Viable PMID:11533231 orf19.1187 CPH2 CAL0002132 Overexpression Viable orf19.1187 CPH2 CAL0002132 Homozygous null Wild-type hyphal growth Normal hyphal growth (liquid + serum, GlcNAc, proline) PMID:11533231 orf19.1187 CPH2 CAL0002132 Homozygous null Wild-type hyphal growth YPD + serum, 37 deg PMID:11595734 orf19.1187 CPH2 CAL0002132 Homozygous null Hyphal growth abnormal Lee media PMID:11595734 orf19.1187 CPH2 CAL0002132 Homozygous null Transcription regulation abnormal PMID:11595734 orf19.1187 CPH2 CAL0002132 Homozygous null Viable Insertion mutation, supplementary data PMID:15964282 orf19.1187 CPH2 CAL0002132 Homozygous null Wild-type biofilm formation Insertion mutation, supplementary data PMID:15964282 orf19.1187 CPH2 CAL0002132 Heterozygous null Viable Barcode deletion set, fitness test (haploinsufficient phenotype assay) PMID:17604452 orf19.119 CAL0003003 Heterozygous null Viable Barcode deletion set, fitness test (haploinsufficient phenotype assay) PMID:17604452 orf19.1190 CAL0002155 Heterozygous null Viable Barcode deletion set, fitness test (haploinsufficient phenotype assay) PMID:17604452 orf19.1191 CAL0002157 Heterozygous null Viable Barcode deletion set, fitness test (haploinsufficient phenotype assay) PMID:17604452 orf19.1192 DNA2 CAL0002159 Heterozygous null Viable Barcode deletion set, fitness test (haploinsufficient phenotype assay) PMID:17604452 orf19.1193 GNP1 CAL0002160 Heterozygous null Viable Barcode deletion set, fitness test (haploinsufficient phenotype assay) PMID:17604452 orf19.1196 CAL0002162 Heterozygous null Viable Barcode deletion set, fitness test (haploinsufficient phenotype assay) PMID:17604452 orf19.1198 CAL0002163 Heterozygous null Viable Barcode deletion set, fitness test (haploinsufficient phenotype assay) PMID:17604452 orf19.1199 NOP5 CAL0002164 Heterozygous null Viable Heterozygous transposon mutant allele PMID:12773383 orf19.1199 NOP5 CAL0002164 Heterozygous null Viable Barcode deletion set, fitness test (haploinsufficient phenotype assay) PMID:17604452 orf19.1201 CAL0002761 Heterozygous null Viable Barcode deletion set, fitness test (haploinsufficient phenotype assay) PMID:17604452 orf19.1204 CAL0002766 Heterozygous null Viable Barcode deletion set, fitness test (haploinsufficient phenotype assay) PMID:17604452 orf19.121 CAL0003027 Heterozygous null Viable Barcode deletion set, fitness test (haploinsufficient phenotype assay) PMID:17604452 orf19.1214 CAL0002793 Heterozygous null Viable Barcode deletion set, fitness test (haploinsufficient phenotype assay) PMID:17604452 orf19.1217 CAL0002796 Heterozygous null Viable Barcode deletion set, fitness test (haploinsufficient phenotype assay) PMID:17604452 orf19.122 CDC20 CAL0003029 Heterozygous null Viable Barcode deletion set, fitness test (haploinsufficient phenotype assay) PMID:17604452 orf19.1220 RVS167 CAL0002827 Depletion Viable large-scale identification of essential genes by gene replacement and conditional expression (GRACE) method PMID:14507372 orf19.1220 RVS167 CAL0002827 Heterozygous null Viable Barcode deletion set, fitness test (haploinsufficient phenotype assay) PMID:17604452 orf19.1221 ALG2 CAL0002829 Heterozygous null Viable Barcode deletion set, fitness test (haploinsufficient phenotype assay) PMID:17604452 orf19.1224 FRP3 CAL0002835 Heterozygous null Viable Barcode deletion set, fitness test (haploinsufficient phenotype assay) PMID:17604452 orf19.1227 CAL0002840 Homozygous null (inferred) Inviable Insertion mutation, supplementary data PMID:15964282 orf19.1229 CAL0002842 Heterozygous null Viable Barcode deletion set, fitness test (haploinsufficient phenotype assay) PMID:17604452 orf19.1232 VRG4 CAL0002875 Depletion Cell morphology abnormal PMID:11741841 orf19.1232 VRG4 CAL0002875 Depletion Cell wall abnormal Defect in cell wall and cell separation PMID:11741841 orf19.1232 VRG4 CAL0002875 Depletion Cell wall abnormal Decreased cell surface phosphomannan PMID:11741841 orf19.1232 VRG4 CAL0002875 Depletion decreased protein mannosylation PMID:11741841 orf19.1232 VRG4 CAL0002875 Depletion Drug susceptibility altered Increased sensitivity to hygromycin B PMID:11741841 orf19.1232 VRG4 CAL0002875 Depletion Hyphal growth abnormal Abolished germ tube induction and hyphal growth; pseudohyphal growth instead (liquid media + serum) PMID:11741841 orf19.1232 VRG4 CAL0002875 Depletion Hyphal growth abnormal Abolished hyphal growth (solid serum or Spider media) PMID:11741841 orf19.1232 VRG4 CAL0002875 Depletion increased cell lysis PMID:11741841 orf19.1232 VRG4 CAL0002875 Homozygous null (inferred) Inviable PMID:11741841 orf19.1232 VRG4 CAL0002875 Depletion Pseudohyphal growth abnormal Increased pseudohyphal growth PMID:11741841 orf19.1232 VRG4 CAL0002875 Depletion wild-type sensitivity to Calcofluor white or sodium vanadate PMID:11741841 orf19.1232 VRG4 CAL0002875 Heterozygous null Viable Barcode deletion set, fitness test (haploinsufficient phenotype assay) PMID:17604452 orf19.1233 ADE4 CAL0002876 Heterozygous null Viable Barcode deletion set, fitness test (haploinsufficient phenotype assay) PMID:17604452 orf19.1234 FGR6-10 CAL0002878 Unknown/unspecified Filamentous growth abnormal Decreased filamentous growth (solid Spider medium); transposon is proximal to, but not within, the ORF PMID:12773383 orf19.1235 HOM3 CAL0002880 Heterozygous null Viable Barcode deletion set, fitness test (haploinsufficient phenotype assay) PMID:17604452 orf19.1236 CAL0002882 Heterozygous null Viable Barcode deletion set, fitness test (haploinsufficient phenotype assay) PMID:17604452 orf19.1237 ARO9 CAL0002883 Heterozygous null Viable Barcode deletion set, fitness test (haploinsufficient phenotype assay) PMID:17604452 orf19.124 CAL0003033 Heterozygous null Viable Barcode deletion set, fitness test (haploinsufficient phenotype assay) PMID:17604452 orf19.1248 CAL0002919 Heterozygous null Viable Barcode deletion set, fitness test (haploinsufficient phenotype assay) PMID:17604452 orf19.1249 CAL0002920 Heterozygous null Viable Barcode deletion set, fitness test (haploinsufficient phenotype assay) PMID:17604452 orf19.125 EBP1 CAL0003035 Homozygous null Viable Mutation has no effect on steroid-induced transcription of CDR1 PMID:14968428 orf19.125 EBP1 CAL0003035 Heterozygous null Viable Barcode deletion set, fitness test (haploinsufficient phenotype assay) PMID:17604452 orf19.1251 CAL0002947 Heterozygous null Viable Barcode deletion set, fitness test (haploinsufficient phenotype assay) PMID:17604452 orf19.1252 YME1 CAL0002950 Homozygous null Viable PMID:14663094 orf19.1252 YME1 CAL0002950 Heterozygous null Viable Barcode deletion set, fitness test (haploinsufficient phenotype assay) PMID:17604452 orf19.1254 SEC23 CAL0002954 Heterozygous null Viable Barcode deletion set, fitness test (haploinsufficient phenotype assay) PMID:17604452 orf19.1255 CAL0002955 Homozygous null Viable Insertion mutation, supplementary data PMID:15964282 orf19.1255 CAL0002955 Homozygous null Wild-type biofilm formation Insertion mutation, supplementary data PMID:15964282 orf19.1261 CGT1 CAL0002984 Heterozygous null Viable PMID:12477801 orf19.1261 CGT1 CAL0002984 Heterozygous null Virulence defect Increased virulence observed in mouse intravenous infection (wild-type virulence in guinea pig intravenous infection and wild-type kidney colonization in mice and guinea pigs) PMID:10708374 orf19.1261 CGT1 CAL0002984 Homozygous null (inferred) Inviable PMID:12477801 orf19.1261 CGT1 CAL0002984 Heterozygous null Slow growth Increased growth lag, but higher final culture density PMID:10708374 orf19.1261 CGT1 CAL0002984 Heterozygous null Drug susceptibility altered Increased resistance to hygromycin B PMID:10708374 orf19.1261 CGT1 CAL0002984 Heterozygous null Colony morphology abnormal Mutant colonies are unusually large and show an "irregular wrinkle" morphology PMID:10708374 orf19.1261 CGT1 CAL0002984 Heterozygous null Heat stress susceptibility altered Increased resistance to heat PMID:10708374 orf19.1261 CGT1 CAL0002984 Heterozygous null Viable Barcode deletion set, fitness test (haploinsufficient phenotype assay) PMID:17604452 orf19.1263 CFL1 CAL0002986 Heterozygous null Viable Barcode deletion set, fitness test (haploinsufficient phenotype assay) PMID:17604452 orf19.1264 CFL2 CAL0002987 Heterozygous null Viable Barcode deletion set, fitness test (haploinsufficient phenotype assay) PMID:17604452 orf19.1267.1 CAF0006921 Heterozygous null Viable Barcode deletion set, fitness test (haploinsufficient phenotype assay) PMID:17604452 orf19.1270 CAL0003015 Heterozygous null Viable Barcode deletion set, fitness test (haploinsufficient phenotype assay) PMID:17604452 orf19.1275 GAT1 CAL0003020 Homozygous null abolished proline induction of GAP1 or UGA4 transcription (defect in nitrogen catabolite repression) PMID:14617156 orf19.1275 GAT1 CAL0003020 Homozygous null Hyphal growth abnormal Slightly delayed germ tube induction (Lee's medium or Media 199) PMID:14617156 orf19.1275 GAT1 CAL0003020 Homozygous null Slow growth Slow growth on isoleucine, tyrosine, or tryptophan nitrogen source PMID:14617156 orf19.1275 GAT1 CAL0003020 Heterozygous null Viable PMID:14617156 orf19.1275 GAT1 CAL0003020 Homozygous null Viable PMID:14617156|PMID:17369441 orf19.1275 GAT1 CAL0003020 Homozygous null Virulence defect Avirulent in mouse systemic infection model PMID:14617156 orf19.1275 GAT1 CAL0003020 Homozygous null wild-type chlamydospore formation PMID:14617156 orf19.1275 GAT1 CAL0003020 Homozygous null wild-type growth rate in 100% serum PMID:14617156 orf19.1275 GAT1 CAL0003020 Homozygous null Wild-type hyphal growth Normal hyphal growth (various solid and liquid media) PMID:14617156 orf19.1275 GAT1 CAL0003020 Heterozygous null Wild-type virulence PMID:14617156 orf19.1275 GAT1 CAL0003020 Heterozygous null Viable Barcode deletion set, fitness test (haploinsufficient phenotype assay) PMID:17604452 orf19.1276 CAL0003021 Homozygous null Viable PMID:14663094 orf19.1277 CAL0003022 Homozygous null Viable PMID:17873081 orf19.1277 CAL0003022 Homozygous null Drug susceptibility altered decreased resistance to caspofungin PMID:17873081 orf19.1279 CDS1 CAL0003024 Heterozygous null Filamentous growth abnormal Decreased filamentous growth (solid Spider medium); heterozygous transposon mutant allele PMID:12773383 orf19.1279 CDS1 CAL0003024 Heterozygous null Viable Heterozygous transposon mutant allele PMID:12773383 orf19.1279 CDS1 CAL0003024 Heterozygous null Viable Barcode deletion set, fitness test (haploinsufficient phenotype assay) PMID:17604452 orf19.1280 SUI1 CAL0003056 Heterozygous null Viable Barcode deletion set, fitness test (haploinsufficient phenotype assay) PMID:17604452 orf19.1282 CAL0003060 Heterozygous null Viable Barcode deletion set, fitness test (haploinsufficient phenotype assay) PMID:17604452 orf19.1283 MEC1 CAL0003061 Heterozygous null Viable Barcode deletion set, fitness test (haploinsufficient phenotype assay) PMID:17604452 orf19.1285 CAL0003062 Heterozygous null Viable Barcode deletion set, fitness test (haploinsufficient phenotype assay) PMID:17604452 orf19.1288 FOX2 CAL0003065 Homozygous null Viable PMID:16963628 orf19.1288 FOX2 CAL0003065 Homozygous null Carbon source utilization defect unable to utilize oleic acid as carbon source PMID:16963628 orf19.1288 FOX2 CAL0003065 Homozygous null Metabolism abnormal strongly reduced fatty acid beta-oxidation PMID:16963628 orf19.1288 FOX2 CAL0003065 Homozygous null Virulence defect attenuated virulence in BALB/c mice systemic infections PMID:16963628 orf19.1288 FOX2 CAL0003065 Homozygous null Carbon source utilization defect severe growth defects on nonfermentable carbon sources PMID:16963628 orf19.1288 FOX2 CAL0003065 Homozygous null Carbon source utilization defect unable to utilize ethanol, oleic, palmitic, linoleic, or myristic acid; poor growth on citrate or glycerol PMID:17158734 orf19.1288 FOX2 CAL0003065 Homozygous null Virulence defect mild decrease in virulence mouse model of hematogenously disseminated candidiasis PMID:17158734 orf19.1291 ABZ1 CAL0003102 Homozygous null Viable PMID:14663094 orf19.1291 ABZ1 CAL0003102 Heterozygous null Viable Barcode deletion set, fitness test (haploinsufficient phenotype assay) PMID:17604452 orf19.1295 VAS1 CAL0003105 Heterozygous null Viable Barcode deletion set, fitness test (haploinsufficient phenotype assay) PMID:17604452 orf19.1299 RPN6 CAL0003109 Heterozygous null Viable Barcode deletion set, fitness test (haploinsufficient phenotype assay) PMID:17604452 orf19.130 CAL0003067 Heterozygous null Viable Barcode deletion set, fitness test (haploinsufficient phenotype assay) PMID:17604452 orf19.1300 CAL0003697 Heterozygous null Viable Barcode deletion set, fitness test (haploinsufficient phenotype assay) PMID:17604452 orf19.1304 CAL0003704 Heterozygous null Viable Barcode deletion set, fitness test (haploinsufficient phenotype assay) PMID:17604452 orf19.1305 CAL0003706 Heterozygous null Viable Barcode deletion set, fitness test (haploinsufficient phenotype assay) PMID:17604452 orf19.1306 CAL0003707 Heterozygous null Viable Barcode deletion set, fitness test (haploinsufficient phenotype assay) PMID:17604452 orf19.1307 CAL0003709 Heterozygous null Viable Barcode deletion set, fitness test (haploinsufficient phenotype assay) PMID:17604452 orf19.1308 CAL0003710 Heterozygous null Viable Barcode deletion set, fitness test (haploinsufficient phenotype assay) PMID:17604452 orf19.1310 CAL0003720 Heterozygous null Viable Barcode deletion set, fitness test (haploinsufficient phenotype assay) PMID:17604452 orf19.1311 SPO75 CAL0003722 Heterozygous null Viable Barcode deletion set, fitness test (haploinsufficient phenotype assay) PMID:17604452 orf19.1313 CDR3 CAL0003726 Homozygous null Viable Wild-type growth PMID:9393682 orf19.1313 CDR3 CAL0003726 Overexpression Viable PMID:9393682 orf19.1313 CDR3 CAL0003726 Overexpression wild-type 4-NQO sensitivity PMID:9393682 orf19.1313 CDR3 CAL0003726 Overexpression wild-type brefeldin A sensitivity PMID:9393682 orf19.1313 CDR3 CAL0003726 Homozygous null Wild-type cell morphology PMID:9393682 orf19.1313 CDR3 CAL0003726 Overexpression wild-type cerulenin sensitivity PMID:9393682 orf19.1313 CDR3 CAL0003726 Overexpression wild-type cycloheximide sensitivity PMID:9393682 orf19.1313 CDR3 CAL0003726 Homozygous null wild-type fluconazole sensitivity PMID:9393682 orf19.1313 CDR3 CAL0003726 Overexpression wild-type fluconazole sensitivity PMID:9393682 orf19.1313 CDR3 CAL0003726 Overexpression wild-type phenanthroline sensitivity PMID:9393682 orf19.1313 CDR3 CAL0003726 Overexpression Drug susceptibility altered Increased resistance to azole drugs PMID:9756759 orf19.1313 CDR3 CAL0003726 Homozygous null Plasma membrane abnormal Increased surface phosphatidylethanolamine PMID:11870854 orf19.1313 CDR3 CAL0003726 Homozygous null Viable PMID:11870854 orf19.1317 OSH3 CAL0003732 Heterozygous null Viable PMID:17082746 orf19.1317 OSH3 CAL0003732 Homozygous null Viable PMID:17082746 orf19.1317 OSH3 CAL0003732 Homozygous null Filamentous growth abnormal Decreased filamentation (solid Spider) PMID:17082746 orf19.1321 HWP1 CAL0003753 Homozygous null Viable PMID:15042589 orf19.1321 HWP1 CAL0003753 Homozygous null Adhesion abnormal Decreased adhesion (human buccal epithelial cells [BEC]) PMID:15262971 orf19.1321 HWP1 CAL0003753 Heterozygous null Virulence defect reduced virulence in murine model of hematogenously disseminated candidiasis PMID:10722594 orf19.1321 HWP1 CAL0003753 Homozygous null Virulence defect severely reduced virulence in murine model of hematogenously disseminated candidiasis PMID:10722594 orf19.1321 HWP1 CAL0003753 Homozygous null Adhesion abnormal Decreased adhesion (human buccal epithelial cells [BEC]); stable attachment mediated by unidentified host transglutaminase PMID:10066176 orf19.1321 HWP1 CAL0003753 Homozygous null Wild-type hyphal growth M199 media PMID:10066176 orf19.1321 HWP1 CAL0003753 Homozygous null Virulence defect Mouse intravenous infection PMID:10066176 orf19.1321 HWP1 CAL0003753 Homozygous null Hyphal growth abnormal nearly complete loss of hyphal growth on solid medium PMID:10464197 orf19.1321 HWP1 CAL0003753 Heterozygous null Hyphal growth abnormal greatly reduced hyphal growth on solid medium PMID:10464197 orf19.1321 HWP1 CAL0003753 Homozygous null wild-type filamentous growth Filamentous growth defect observed in previous studies was shown to be due to URA3 effects, independent of HWP1 PMID:15817775 orf19.1321 HWP1 CAL0003753 Homozygous null Wild-type virulence Defect observed in previous studies was shown to be due to URA3 effects, independent of HWP1 PMID:15817775 orf19.1321 HWP1 CAL0003753 Homozygous null Virulence defect Mouse intravenous infection; URA3 marker also influences virulence in this model PMID:12011025 orf19.1321 HWP1 CAL0003753 Heterozygous null Wild-type virulence Mouse intravenous infection PMID:12011025 orf19.1321 HWP1 CAL0003753 Homozygous null Biofilm formation abnormal severe biofilm formation defect in vivo (rat venous catheter model) PMID:17030992 orf19.1321 HWP1 CAL0003753 Homozygous null Wild-type adhesion human FaDU oropharyngeal epithelial cells PMID:15042589 orf19.1323 CAL0003756 Heterozygous null Viable Barcode deletion set, fitness test (haploinsufficient phenotype assay) PMID:17604452 orf19.1324 RAD2 CAL0003758 Heterozygous null Viable Barcode deletion set, fitness test (haploinsufficient phenotype assay) PMID:17604452 orf19.1325 ECM38 CAL0003759 Heterozygous null Viable Barcode deletion set, fitness test (haploinsufficient phenotype assay) PMID:17604452 orf19.1327 RBT1 CAL0003763 Heterozygous null Viable PMID:10978273 orf19.1327 RBT1 CAL0003763 Homozygous null Viable No apparent growth defects under various laboratory conditions PMID:10978273 orf19.1327 RBT1 CAL0003763 Heterozygous null Virulence defect Decreased virulence in mouse systemic infection model PMID:10978273 orf19.1327 RBT1 CAL0003763 Homozygous null Virulence defect Decreased virulence in mouse systemic infection model PMID:10978273 orf19.1327 RBT1 CAL0003763 Homozygous null Virulence defect Decreased virulence in rabbit corneal infection model PMID:10978273 orf19.1327 RBT1 CAL0003763 Homozygous null Viable PMID:14663094 orf19.1331 HSM3 CAL0003786 Homozygous null Viable PMID:14663094 orf19.1332 CAL0003788 Heterozygous null Viable Barcode deletion set, fitness test (haploinsufficient phenotype assay) PMID:17604452 orf19.1333 SNG3 CAL0003790 Heterozygous null Viable Barcode deletion set, fitness test (haploinsufficient phenotype assay) PMID:17604452 orf19.1335 CAL0003794 Heterozygous null Viable Barcode deletion set, fitness test (haploinsufficient phenotype assay) PMID:17604452 orf19.1341 CAL0003821 Heterozygous null Viable Barcode deletion set, fitness test (haploinsufficient phenotype assay) PMID:17604452 orf19.1342 SHM1 CAL0003822 Heterozygous null Viable Barcode deletion set, fitness test (haploinsufficient phenotype assay) PMID:17604452 orf19.1345 LIP8 CAL0003827 Homozygous null Viable PMID:17646357 orf19.1345 LIP8 CAL0003827 Homozygous null Flocculence increased flocculation PMID:17646357 orf19.1345 LIP8 CAL0003827 Homozygous null Colony morphology abnormal colonies with wrinkled center PMID:17646357 orf19.1345 LIP8 CAL0003827 Overexpression Colony morphology abnormal increased mycelial growth in outer regions of colonies PMID:17646357 orf19.1345 LIP8 CAL0003827 Homozygous null Virulence defect decreased virulence in mouse systemic infection model PMID:17646357 orf19.1345 LIP8 CAL0003827 Heterozygous null Viable Barcode deletion set, fitness test (haploinsufficient phenotype assay) PMID:17604452 orf19.135 CAL0003078 Heterozygous null Viable Barcode deletion set, fitness test (haploinsufficient phenotype assay) PMID:17604452 orf19.1352 CAL0003855 Heterozygous null Viable Barcode deletion set, fitness test (haploinsufficient phenotype assay) PMID:17604452 orf19.1355 CAL0003859 Heterozygous null Viable Barcode deletion set, fitness test (haploinsufficient phenotype assay) PMID:17604452 orf19.1357 FCY21 CAL0003863 Heterozygous null Viable Barcode deletion set, fitness test (haploinsufficient phenotype assay) PMID:17604452 orf19.1358 GCN4 CAL0003864 Homozygous null Viable PMID:12374745 orf19.1358 GCN4 CAL0003864 Overexpression Filamentous growth abnormal Filamentous growth without induction PMID:12374745 orf19.1358 GCN4 CAL0003864 Homozygous null Filamentous growth abnormal Abolished filament induction by amino acid starvation PMID:12374745 orf19.1358 GCN4 CAL0003864 Homozygous null Wild-type hyphal growth Normal hyphal induction by serum PMID:12374745 orf19.1358 GCN4 CAL0003864 Overexpression Drug susceptibility altered Increased resistance to 3-aminotriazole PMID:12374745 orf19.1358 GCN4 CAL0003864 Homozygous null Drug susceptibility altered Increased sensitivity to 3-aminotriazole PMID:12374745|PMID:15701793 orf19.1358 GCN4 CAL0003864 Overexpression Colony morphology abnormal Wrinkled colony morphology PMID:12374745 orf19.1358 GCN4 CAL0003864 Overexpression Transcription regulation abnormal PCL5 induction PMID:15701793 orf19.1358 GCN4 CAL0003864 Homozygous null Filamentous growth abnormal Filamentation defect (solid Lee medium) PMID:15701793 orf19.1358 GCN4 CAL0003864 Homozygous null Hyphal growth abnormal Hyphal induction defect (liquid Lee medium) PMID:15701793 orf19.1358 GCN4 CAL0003864 Heterozygous null Wild-type virulence Mutant shows wild-type virulence (mouse intravenous infection); however, URA3 position effect caused by construction of the mutant strain causes a spurious effect on virulence in this assay PMID:15302823 orf19.1358 GCN4 CAL0003864 Homozygous null Wild-type virulence Mutant shows wild-type virulence (mouse intravenous infection); however, URA3 position effect caused by construction of the mutant strain causes a spurious effect on virulence in this assay PMID:15302823 orf19.1358 GCN4 CAL0003864 Homozygous null Slow growth PMID:15075282 orf19.1358 GCN4 CAL0003864 Homozygous null Biofilm formation abnormal Decreased biofilm formation PMID:15075282 orf19.1358 GCN4 CAL0003864 Homozygous null Wild-type hyphal growth Wild-type proportion of hyphal cells in the mutant biofilm PMID:15075282 orf19.1358 GCN4 CAL0003864 Homozygous null Transcription regulation abnormal Large-scale experimental measurement of protein abundance PMID:15274137 orf19.1358 GCN4 CAL0003864 Homozygous null Drug susceptibility altered Response to 3-aminotriazole, which mimics histidine starvation and induces GCN response; large-scale experimental measurement of protein abundance PMID:15274137 orf19.1358 GCN4 CAL0003864 Homozygous null Transcription regulation abnormal Transcript profiling data PMID:16215176 orf19.1358 GCN4 CAL0003864 Homozygous null Response to amino acid starvation abnormal Slow growth in absence of amino acids PMID:16215176 orf19.1358 GCN4 CAL0003864 Homozygous null Transcription regulation abnormal Transcript profiles PMID:16215176 orf19.1358 GCN4 CAL0003864 Homozygous null Viable Insertion mutation, supplementary data PMID:15964282 orf19.1358 GCN4 CAL0003864 Homozygous null Wild-type biofilm formation Insertion mutation, supplementary data PMID:15964282 orf19.136 CAL0003080 Heterozygous null Viable Barcode deletion set, fitness test (haploinsufficient phenotype assay) PMID:17604452 orf19.1361 CAL0003881 Heterozygous null Viable Barcode deletion set, fitness test (haploinsufficient phenotype assay) PMID:17604452 orf19.1362 CAL0003882 Heterozygous null Viable Barcode deletion set, fitness test (haploinsufficient phenotype assay) PMID:17604452 orf19.1363 CAL0003883 Heterozygous null Viable Barcode deletion set, fitness test (haploinsufficient phenotype assay) PMID:17604452 orf19.1365 CAL0003885 Heterozygous null Viable Barcode deletion set, fitness test (haploinsufficient phenotype assay) PMID:17604452 orf19.1366 CAL0003886 Heterozygous null Viable Barcode deletion set, fitness test (haploinsufficient phenotype assay) PMID:17604452 orf19.1369 CAL0003889 Heterozygous null Viable Barcode deletion set, fitness test (haploinsufficient phenotype assay) PMID:17604452 orf19.137 CAL0003081 Heterozygous null Viable Barcode deletion set, fitness test (haploinsufficient phenotype assay) PMID:17604452 orf19.1375 LEU42 CAL0003911 Heterozygous null Viable Barcode deletion set, fitness test (haploinsufficient phenotype assay) PMID:17604452 orf19.1378 SUP35 CAL0003914 Heterozygous null Viable Barcode deletion set, fitness test (haploinsufficient phenotype assay) PMID:17604452 orf19.138 FIG1 CAL0003084 Homozygous null Hyphal growth abnormal abnormal directional growth of hyphae PMID:17275302 orf19.1381 CAL0003939 Heterozygous null Viable Barcode deletion set, fitness test (haploinsufficient phenotype assay) PMID:17604452 orf19.1382 YEA4 CAL0003940 Heterozygous null Viable Barcode deletion set, fitness test (haploinsufficient phenotype assay) PMID:17604452 orf19.1386 CAL0003943 Heterozygous null Viable Barcode deletion set, fitness test (haploinsufficient phenotype assay) PMID:17604452 orf19.1387 CAL0003944 Heterozygous null Viable Barcode deletion set, fitness test (haploinsufficient phenotype assay) PMID:17604452 orf19.1388 CAL0003945 Heterozygous null Viable Barcode deletion set, fitness test (haploinsufficient phenotype assay) PMID:17604452 orf19.1389 CAL0003946 Heterozygous null Viable Barcode deletion set, fitness test (haploinsufficient phenotype assay) PMID:17604452 orf19.1390 PMI1 CAL0003967 Homozygous null Viable PMID:7785330 orf19.1390 PMI1 CAL0003967 Homozygous null D-mannose auxotrophy In absence of exogenous D-mannose cells exhibit abnormal, swollen morphology and defect in cell separation PMID:7785330 orf19.1390 PMI1 CAL0003967 Heterozygous null Viable PMID:7785330 orf19.1390 PMI1 CAL0003967 Point Drug susceptibility altered C150A mutant enzyme activity is resistant to mercury and silver, shows wild-type phosphomannose isomerase activity PMID:7794901 orf19.1390 PMI1 CAL0003967 Heterozygous null Viable Barcode deletion set, fitness test (haploinsufficient phenotype assay) PMID:17604452 orf19.1394 CAL0003971 Homozygous null Viable PMID:14663094 orf19.1395 CAL0003972 Heterozygous null Viable Barcode deletion set, fitness test (haploinsufficient phenotype assay) PMID:17604452 orf19.1400 CAL0004448 Heterozygous null Viable Barcode deletion set, fitness test (haploinsufficient phenotype assay) PMID:17604452 orf19.1401 EAP1 CAL0004450 Homozygous null Viable PMID:17416898 orf19.1401 EAP1 CAL0004450 Homozygous null Biofilm formation abnormal Reduced biofilm formation in in vitro and in vivo assays PMID:17416898 orf19.1401 EAP1 CAL0004450 Homozygous null Adhesion abnormal Decreased adhesion to polystyrene and to HEK293 kidney epithelial cell monolayers PMID:17416898 orf19.1401 EAP1 CAL0004450 Heterozygous null Viable Barcode deletion set, fitness test (haploinsufficient phenotype assay) PMID:17604452 orf19.1402 CAL0004452 Heterozygous null Viable Barcode deletion set, fitness test (haploinsufficient phenotype assay) PMID:17604452 orf19.1409 VAC7 CAL0004468 Homozygous null Viable PMID:14663094 orf19.1411 CAL0004478 Heterozygous null Viable Barcode deletion set, fitness test (haploinsufficient phenotype assay) PMID:17604452 orf19.1413 YFH1 CAL0004482 Homozygous null Viable PMID:15469520 orf19.1413 YFH1 CAL0004482 Homozygous null Slow growth Severe growth defect in both minimal and rich medium PMID:15469520 orf19.1413 YFH1 CAL0004482 Homozygous null Metabolism abnormal Elevated secretion of flavins resulting in deep yellow culture supernatant PMID:15469520 orf19.1413 YFH1 CAL0004482 Homozygous null Abnormal iron uptake Elevated iron uptake PMID:15469520 orf19.1413 YFH1 CAL0004482 Homozygous null Cell morphology abnormal Abnormal mitochondrial morphology PMID:15469520 orf19.1413 YFH1 CAL0004482 Homozygous null Oxidative stress susceptibility altered Elevated sensitivity to paraquat and hydrogen peroxide PMID:15469520 orf19.1413 YFH1 CAL0004482 Homozygous null Oxidative stress susceptibility altered Accumulation of reactive oxygen species (ROS) PMID:15469520 orf19.1413 YFH1 CAL0004482 Heterozygous null Viable Barcode deletion set, fitness test (haploinsufficient phenotype assay) PMID:17604452 orf19.1415 FRE10 CAL0004487 Homozygous null Viable No apparent growth defects under various laboratory conditions PMID:10978273 orf19.1415 FRE10 CAL0004487 Homozygous null Wild-type virulence Rabbit cornea infection PMID:10978273 orf19.1415 FRE10 CAL0004487 Homozygous null Abnormal iron uptake Decreased iron uptake from transferrin or ferric chloride iron source; decreased growth rate using holotransferrin iron source at pH 4.3-4.4, but no significant defect using holotransferrin, ferric ammonium sulfate, or ferrichrome at pH 6.3-6.4 PMID:16113264 orf19.1415 FRE10 CAL0004487 Homozygous null Protein activity abnormal Decreased cell surface reductase activity toward ferric ammonium sulfate substrate (reconstituted strain shows wild-type activity) PMID:16113264 orf19.1419 CAL0004497 Heterozygous null Viable Barcode deletion set, fitness test (haploinsufficient phenotype assay) PMID:17604452 orf19.1421 CAL0004516 Heterozygous null Viable Barcode deletion set, fitness test (haploinsufficient phenotype assay) PMID:17604452 orf19.1422 FZO1 CAL0004518 Heterozygous null Viable Barcode deletion set, fitness test (haploinsufficient phenotype assay) PMID:17604452 orf19.1427 CAL0004528 Heterozygous null Viable Barcode deletion set, fitness test (haploinsufficient phenotype assay) PMID:17604452 orf19.1434 CAL0004555 Heterozygous null Viable Barcode deletion set, fitness test (haploinsufficient phenotype assay) PMID:17604452 orf19.144 SNU114 CAL0003115 Homozygous null Inviable PMID:12524333 orf19.144 SNU114 CAL0003115 Heterozygous null Viable Barcode deletion set, fitness test (haploinsufficient phenotype assay) PMID:17604452 orf19.1442 PLB4.5 CAL0004588 Heterozygous null Viable Barcode deletion set, fitness test (haploinsufficient phenotype assay) PMID:17604452 orf19.1445 ESC4 CAL0004594 Heterozygous null Filamentous growth abnormal Increased filamentous growth (solid Spider medium); heterozygous transposon mutant allele or heterozygous deletion allele PMID:12773383 orf19.1445 ESC4 CAL0004594 Heterozygous null Viable Heterozygous deletion allele, heterozygous transposon mutant allele PMID:12773383 orf19.1445 ESC4 CAL0004594 Heterozygous null Viable Barcode deletion set, fitness test (haploinsufficient phenotype assay) PMID:17604452 orf19.1446 CLB2 CAL0004596 Heterozygous null Viable PMID:15888543 orf19.1446 CLB2 CAL0004596 Homozygous null (inferred) Inviable PMID:15888543 orf19.1446 CLB2 CAL0004596 Depletion Inviable Cell-cycle arrest in late anaphase/telophase as elongated filamentous, dinucleate cells with polarized cortical actin patches, indicating a mitotic exit defect PMID:15888543 orf19.1446 CLB2 CAL0004596 Depletion Wild-type hyphal growth Germ tube induction in response to serum PMID:15888543 orf19.1446 CLB2 CAL0004596 Overexpression Hyphal growth abnormal Fewer, shorter germ tubes (serum induction) PMID:15888543 orf19.1446 CLB2 CAL0004596 Dominant negative Inviable Mutant lacking the destruction box shows dominant inviability; terminal phenotype shows branching, elongated buds (increased polarized growth without cytokinesis) PMID:15888543 orf19.1446 CLB2 CAL0004596 Heterozygous null Viable Barcode deletion set, fitness test (haploinsufficient phenotype assay) PMID:17604452 orf19.1448 APT1 CAL0004599 Heterozygous null Viable Barcode deletion set, fitness test (haploinsufficient phenotype assay) PMID:17604452 orf19.1449 CAL0004600 Heterozygous null Viable Barcode deletion set, fitness test (haploinsufficient phenotype assay) PMID:17604452 orf19.145 RPB4 CAL0003117 Heterozygous null Viable Heterozygous transposon mutant allele PMID:12773383 orf19.1451 SRB9 CAL0004613 Unknown/unspecified Filamentous growth abnormal Decreased filamentous growth (solid Spider medium); transposon is proximal to, but not within, the ORF PMID:12773383 orf19.1453 SPT5 CAL0004616 Heterozygous null Filamentous growth abnormal Decreased filamentous growth (solid Spider medium); heterozygous transposon mutant allele PMID:12773383 orf19.1453 SPT5 CAL0004616 Unknown/unspecified Filamentous growth abnormal Decreased filamentous growth (solid Spider medium); transposon is proximal to, but not within, the ORF PMID:12773383 orf19.1453 SPT5 CAL0004616 Heterozygous null Viable Heterozygous transposon mutant allele PMID:12773383 orf19.1453 SPT5 CAL0004616 Heterozygous null Viable Barcode deletion set, fitness test (haploinsufficient phenotype assay) PMID:17604452 orf19.1457 CAL0004620 Heterozygous null Viable Barcode deletion set, fitness test (haploinsufficient phenotype assay) PMID:17604452 orf19.1458 CAL0004621 Heterozygous null Viable Barcode deletion set, fitness test (haploinsufficient phenotype assay) PMID:17604452 orf19.1459 PPE1 CAL0004622 Heterozygous null Viable Barcode deletion set, fitness test (haploinsufficient phenotype assay) PMID:17604452 orf19.1460 CAL0004651 Heterozygous null Viable Barcode deletion set, fitness test (haploinsufficient phenotype assay) PMID:17604452 orf19.1462 SMP2 CAL0004653 Heterozygous null Viable Barcode deletion set, fitness test (haploinsufficient phenotype assay) PMID:17604452 orf19.1465 CAL0004655 Heterozygous null Viable Barcode deletion set, fitness test (haploinsufficient phenotype assay) PMID:17604452 orf19.1466 CAL0004656 Heterozygous null Viable Barcode deletion set, fitness test (haploinsufficient phenotype assay) PMID:17604452 orf19.1468 CAL0004658 Heterozygous null Viable Barcode deletion set, fitness test (haploinsufficient phenotype assay) PMID:17604452 orf19.147 CAL0003123 Heterozygous null Viable Barcode deletion set, fitness test (haploinsufficient phenotype assay) PMID:17604452 orf19.1477 CAL0004693 Heterozygous null Viable Barcode deletion set, fitness test (haploinsufficient phenotype assay) PMID:17604452 orf19.1478 CAL0004694 Heterozygous null Viable Barcode deletion set, fitness test (haploinsufficient phenotype assay) PMID:17604452 orf19.1480 CAL0004732 Heterozygous null Viable Barcode deletion set, fitness test (haploinsufficient phenotype assay) PMID:17604452 orf19.1490 MSB2 CAL0004775 Homozygous null Viable PMID:17873081 orf19.1490 MSB2 CAL0004775 Homozygous null Drug susceptibility altered decreased resistance to caspofungin PMID:17873081 orf19.1490 MSB2 CAL0004775 Heterozygous null Viable Barcode deletion set, fitness test (haploinsufficient phenotype assay) PMID:17604452 orf19.1491 CAL0004776 Heterozygous null Viable Barcode deletion set, fitness test (haploinsufficient phenotype assay) PMID:17604452 orf19.1492 CAL0004777 Heterozygous null Viable Barcode deletion set, fitness test (haploinsufficient phenotype assay) PMID:17604452 orf19.1493 RAD7 CAL0004778 Heterozygous null Viable Barcode deletion set, fitness test (haploinsufficient phenotype assay) PMID:17604452 orf19.1494 RAD23 CAL0004779 Heterozygous null Viable Barcode deletion set, fitness test (haploinsufficient phenotype assay) PMID:17604452 orf19.1495 CAL0004780 Heterozygous null Viable Barcode deletion set, fitness test (haploinsufficient phenotype assay) PMID:17604452 orf19.1496 CAL0004781 Homozygous null Viable Insertion mutation, supplementary data PMID:15964282 orf19.1496 CAL0004781 Homozygous null Wild-type biofilm formation Insertion mutation, supplementary data PMID:15964282 orf19.1497 CAL0004782 Homozygous null Viable Insertion mutation, supplementary data PMID:15964282 orf19.1497 CAL0004782 Homozygous null Wild-type biofilm formation Insertion mutation, supplementary data PMID:15964282 orf19.150 CAL0003142 Heterozygous null Viable Barcode deletion set, fitness test (haploinsufficient phenotype assay) PMID:17604452 orf19.1504 CAL0005383 Heterozygous null Viable Barcode deletion set, fitness test (haploinsufficient phenotype assay) PMID:17604452 orf19.1505 CAL0005385 Homozygous null Viable PMID:14663094 orf19.1509 ROD1 CAL0005393 Homozygous null Viable PMID:14663094 orf19.1509 ROD1 CAL0005393 Heterozygous null Viable Barcode deletion set, fitness test (haploinsufficient phenotype assay) PMID:17604452 orf19.151 TPO5 CAL0003144 Heterozygous null Viable Barcode deletion set, fitness test (haploinsufficient phenotype assay) PMID:17604452 orf19.1510 CAL0005401 Homozygous null Viable PMID:14663094 orf19.1513 FAB1 CAL0005404 Homozygous null Cell morphology abnormal Enlarged vacuoles PMID:12117957 orf19.1513 FAB1 CAL0005404 Homozygous null decreased vacuolar acidification PMID:12117957 orf19.1513 FAB1 CAL0005404 Homozygous null Hyphal growth abnormal Abolished hyphal growth on solid media (solid Spider medium plus mannitol) PMID:12117957 orf19.1513 FAB1 CAL0005404 Homozygous null Hyphal growth abnormal Abolished hyphal growth on solid media (solid YPD media plus serum) PMID:12117957 orf19.1513 FAB1 CAL0005404 Homozygous null increased population of binucleate cells PMID:12117957 orf19.1513 FAB1 CAL0005404 Homozygous null Slow growth PMID:12117957 orf19.1513 FAB1 CAL0005404 Homozygous null Viable PMID:12117957 orf19.1513 FAB1 CAL0005404 Homozygous null wild-type heat sensitivity PMID:12117957 orf19.1513 FAB1 CAL0005404 Homozygous null Wild-type hyphal growth Normal hyphal induction in liquid media (liquid Spider media, or YPD media plus serum) PMID:12117957 orf19.1513 FAB1 CAL0005404 Homozygous null wild-type osmotic stress sensitivity PMID:12117957 orf19.1513 FAB1 CAL0005404 Homozygous null Wild-type virulence Mouse intravenous infection PMID:12117957 orf19.1513 FAB1 CAL0005404 Homozygous null Wild-type adhesion HeLa cells PMID:12117957 orf19.1513 FAB1 CAL0005404 Heterozygous null Viable Barcode deletion set, fitness test (haploinsufficient phenotype assay) PMID:17604452 orf19.1514 CAL0005407 Heterozygous null Viable Barcode deletion set, fitness test (haploinsufficient phenotype assay) PMID:17604452 orf19.1515 CHT4 CAL0005409 Homozygous null Viable No apparent mutant phenotype PMID:16214381 orf19.1515 CHT4 CAL0005409 Heterozygous null Viable PMID:16214381 orf19.1515 CHT4 CAL0005409 Heterozygous null Viable Barcode deletion set, fitness test (haploinsufficient phenotype assay) PMID:17604452 orf19.1516 CAL0005412 Heterozygous null Viable Barcode deletion set, fitness test (haploinsufficient phenotype assay) PMID:17604452 orf19.1517 ARO3 CAL0005414 Homozygous null Viable PMID:8625423 orf19.1523 CAL0005437 Heterozygous null Viable Barcode deletion set, fitness test (haploinsufficient phenotype assay) PMID:17604452 orf19.1524 SPR3 CAL0005440 Homozygous null Viable No apparent phenotype PMID:12181342 orf19.1524 SPR3 CAL0005440 Homozygous null wild-type chlamydospore formation PMID:16002645 orf19.1524 SPR3 CAL0005440 Heterozygous null Viable Barcode deletion set, fitness test (haploinsufficient phenotype assay) PMID:17604452 orf19.1526 SNF2 CAL0005444 Homozygous null Viable PMID:16647065 orf19.1526 SNF2 CAL0005444 Homozygous null Hyphal growth abnormal most cells fail to form hyphae on either serum or Lees medium, and on solid media PMID:16647065 orf19.1526 SNF2 CAL0005444 Homozygous null Colony morphology abnormal irregular and wrinkled PMID:16647065 orf19.1526 SNF2 CAL0005444 Homozygous null Virulence defect avirulent in mice PMID:16647065 orf19.153 CAL0003147 Heterozygous null Viable Barcode deletion set, fitness test (haploinsufficient phenotype assay) PMID:17604452 orf19.1531 CAL0005466 Heterozygous null Viable Barcode deletion set, fitness test (haploinsufficient phenotype assay) PMID:17604452 orf19.1538 TLG2 CAL0005480 Heterozygous null Viable Barcode deletion set, fitness test (haploinsufficient phenotype assay) PMID:17604452 orf19.1541 CAL0005499 Homozygous null Viable PMID:14663094 orf19.1542 HEX3 CAL0005501 Unknown/unspecified Filamentous growth abnormal Decreased filamentous growth (solid Spider medium); transposon is proximal to, but not within, the ORF PMID:12773383 orf19.1542 HEX3 CAL0005501 Heterozygous null Viable Barcode deletion set, fitness test (haploinsufficient phenotype assay) PMID:17604452 orf19.1548 CAL0005511 Heterozygous null Viable Barcode deletion set, fitness test (haploinsufficient phenotype assay) PMID:17604452 orf19.1555 SAC3 CAL0005530 Heterozygous null Viable Barcode deletion set, fitness test (haploinsufficient phenotype assay) PMID:17604452 orf19.1559 HOM2 CAL0005534 Heterozygous null Viable Barcode deletion set, fitness test (haploinsufficient phenotype assay) PMID:17604452 orf19.156 FGR51 CAL0003154 Heterozygous null Filamentous growth abnormal Increased filamentous growth and small colony (solid Spider medium); heterozygous transposon mutant allele PMID:12773383 orf19.156 FGR51 CAL0003154 Heterozygous null Viable Heterozygous transposon mutant allele PMID:12773383 orf19.1560 POB3 CAL0005561 Heterozygous null Filamentous growth abnormal Increased filamentous growth (solid Spider medium); heterozygous transposon mutant allele PMID:12773383 orf19.1560 POB3 CAL0005561 Heterozygous null Viable Heterozygous transposon mutant allele PMID:12773383 orf19.1560 POB3 CAL0005561 Heterozygous null Viable Barcode deletion set, fitness test (haploinsufficient phenotype assay) PMID:17604452 orf19.1563 ECM3 CAL0005563 Homozygous null Viable PMID:17873081 orf19.1564 CAL0005564 Heterozygous null Viable Barcode deletion set, fitness test (haploinsufficient phenotype assay) PMID:17604452 orf19.1565 CAL0005565 Homozygous null Viable Insertion mutation, supplementary data PMID:15964282 orf19.1565 CAL0005565 Homozygous null Wild-type biofilm formation Insertion mutation, supplementary data PMID:15964282 orf19.1568 CAL0005568 Heterozygous null Viable Barcode deletion set, fitness test (haploinsufficient phenotype assay) PMID:17604452 orf19.1569 CAL0005569 Heterozygous null Viable Barcode deletion set, fitness test (haploinsufficient phenotype assay) PMID:17604452 orf19.1570 ERG7 CAL0005598 Heterozygous null Viable Barcode deletion set, fitness test (haploinsufficient phenotype assay) PMID:17604452 orf19.1573 CAL0005601 Heterozygous null Viable Barcode deletion set, fitness test (haploinsufficient phenotype assay) PMID:17604452 orf19.1574 CAL0005602 Heterozygous null Viable Barcode deletion set, fitness test (haploinsufficient phenotype assay) PMID:17604452 orf19.1575 PRS1 CAL0005603 Homozygous null (inferred) Inviable PMID:9402522 orf19.1575 PRS1 CAL0005603 Heterozygous null Protein activity abnormal Decreased phosphoribosylpyrophosphate synthetase activity PMID:9402522 orf19.1575 PRS1 CAL0005603 Heterozygous null Viable No obvious growth or filamentation defect PMID:9402522 orf19.1575 PRS1 CAL0005603 Depletion Inviable large-scale identification of essential genes by gene replacement and conditional expression (GRACE) method PMID:14507372 orf19.1575 PRS1 CAL0005603 Heterozygous null Viable Barcode deletion set, fitness test (haploinsufficient phenotype assay) PMID:17604452 orf19.1576 CAL0005604 Heterozygous null Viable Barcode deletion set, fitness test (haploinsufficient phenotype assay) PMID:17604452 orf19.1578 CAL0005606 Heterozygous null Viable Barcode deletion set, fitness test (haploinsufficient phenotype assay) PMID:17604452 orf19.158 CAL0003160 Heterozygous null Viable Barcode deletion set, fitness test (haploinsufficient phenotype assay) PMID:17604452 orf19.1580 CAL0005638 Heterozygous null Viable Barcode deletion set, fitness test (haploinsufficient phenotype assay) PMID:17604452 orf19.1583 CAL0005641 Heterozygous null Viable Barcode deletion set, fitness test (haploinsufficient phenotype assay) PMID:17604452 orf19.1584 CAL0005642 Heterozygous null Viable Barcode deletion set, fitness test (haploinsufficient phenotype assay) PMID:17604452 orf19.1585 ZRT2 CAL0005643 Heterozygous null Viable Barcode deletion set, fitness test (haploinsufficient phenotype assay) PMID:17604452 orf19.1586 FGR22 CAL0005644 Heterozygous null Filamentous growth abnormal Increased filamentous growth (solid Spider medium, solid YEPD + serum); heterozygous deletion allele PMID:12773383 orf19.1586 FGR22 CAL0005644 Unknown/unspecified Filamentous growth abnormal Increased filamentous growth (solid Spider medium, solid YEPD + serum); transposon is proximal to, but not within, the ORF PMID:12773383 orf19.1586 FGR22 CAL0005644 Heterozygous null Viable Heterozygous deletion allele PMID:12773383 orf19.1586 FGR22 CAL0005644 Homozygous null Viable Wild-type growth (minimal or rich media and many conditions tested) PMID:16207920 orf19.1586 FGR22 CAL0005644 Heterozygous null Viable Barcode deletion set, fitness test (haploinsufficient phenotype assay) PMID:17604452 orf19.1587 HGT20 CAL0005645 Heterozygous null Viable Barcode deletion set, fitness test (haploinsufficient phenotype assay) PMID:17604452 orf19.1589 CAL0005647 Homozygous null Viable Insertion mutation, supplementary data PMID:15964282 orf19.1589 CAL0005647 Homozygous null Wild-type biofilm formation Insertion mutation, supplementary data PMID:15964282 orf19.1589 CAL0005647 Heterozygous null Viable Barcode deletion set, fitness test (haploinsufficient phenotype assay) PMID:17604452 orf19.1591 ERG10 CAL0005678 Heterozygous null Viable Barcode deletion set, fitness test (haploinsufficient phenotype assay) PMID:17604452 orf19.1593 CAL0005680 Homozygous null Viable PMID:14663094 orf19.1593 CAL0005680 Heterozygous null Viable Barcode deletion set, fitness test (haploinsufficient phenotype assay) PMID:17604452 orf19.1596 FGR28 CAL0005683 Unknown/unspecified Filamentous growth abnormal Increased filamentous growth (solid Spider medium, solid YEPD + serum); transposon is proximal to, but not within, the ORF PMID:12773383 orf19.1597 ABG1 CAL0005684 Heterozygous null defect in cell separation Budded daughter cells fail to separate; chains of cells of decreasing size are observed under conditions that favor yeast-form growth PMID:15947201 orf19.1597 ABG1 CAL0005684 Overexpression Viable No obvious phenotype PMID:15947201 orf19.1597 ABG1 CAL0005684 Heterozygous null Viable PMID:15947201 orf19.1597 ABG1 CAL0005684 Homozygous null (inferred) Inviable PMID:15947201 orf19.1597 ABG1 CAL0005684 Depletion Inviable PMID:15947201 orf19.1597 ABG1 CAL0005684 Depletion Hyphal growth abnormal Increased branching frequency under hyphae-inducing conditions PMID:15947201 orf19.1597 ABG1 CAL0005684 Depletion defect in cell separation Budded daughter cells fail to separate; chains of cells of decreasing size are observed under conditions that favor yeast-form growth PMID:15947201 orf19.1597 ABG1 CAL0005684 Depletion Abnormal vacuolar morphology Small, "collapsed" vacuole in yeast-form; small, fragmented vacuole in hyphal form PMID:15947201 orf19.1597 ABG1 CAL0005684 Depletion Cell wall abnormal Increased sensitivity to Calcofluor white and Congo red; decreased sensitivity to SDS PMID:15947201 orf19.1597 ABG1 CAL0005684 Heterozygous null Cell wall abnormal Increased sensitivity to Calcofluor white PMID:15947201 orf19.1598 ERG24 CAL0005685 Homozygous null Drug susceptibility altered Increased resistance to azole drugs PMID:11897574 orf19.1598 ERG24 CAL0005685 Homozygous null Drug susceptibility altered Hypersensitivity to cycloheximide PMID:11897574 orf19.1598 ERG24 CAL0005685 Homozygous null Drug susceptibility altered Hypersensitivity to fluphenazine PMID:11897574 orf19.1598 ERG24 CAL0005685 Homozygous null Drug susceptibility altered Hypersensitivity to cerulenin PMID:11897574 orf19.1598 ERG24 CAL0005685 Homozygous null Drug susceptibility altered Hypersensitivity to brefeldin A PMID:11897574 orf19.1598 ERG24 CAL0005685 Homozygous null Hyphal growth abnormal Abolished germ tube formation in response to serum PMID:11897574 orf19.1598 ERG24 CAL0005685 Homozygous null Slow growth PMID:11897574 orf19.1598 ERG24 CAL0005685 Homozygous null Viable PMID:11897574 orf19.1598 ERG24 CAL0005685 Homozygous null Virulence defect Decreased virulence in mouse systemic infection model PMID:11897574 orf19.1598 ERG24 CAL0005685 Depletion Viable large-scale identification of essential genes by gene replacement and conditional expression (GRACE) method PMID:14507372 orf19.1598 ERG24 CAL0005685 Heterozygous null Viable Barcode deletion set, fitness test (haploinsufficient phenotype assay) PMID:17604452 orf19.1601 RPL3 CAL0006304 Heterozygous null Viable Barcode deletion set, fitness test (haploinsufficient phenotype assay) PMID:17604452 orf19.1607 ALR1 CAL0006317 Heterozygous null Viable Barcode deletion set, fitness test (haploinsufficient phenotype assay) PMID:17604452 orf19.1608 CAL0006319 Heterozygous null Viable Barcode deletion set, fitness test (haploinsufficient phenotype assay) PMID:17604452 orf19.1609 CAL0006321 Heterozygous null Viable Barcode deletion set, fitness test (haploinsufficient phenotype assay) PMID:17604452 orf19.1613 ILV2 CAL0006335 Heterozygous null Viable Barcode deletion set, fitness test (haploinsufficient phenotype assay) PMID:17604452 orf19.1614 MEP1 CAL0006337 Homozygous null Viable PMID:14663094 orf19.1614 MEP1 CAL0006337 Homozygous null Viable A mep1 mep2 double homozygous null mutant lacks ammonium permease activity and has a nitrogen utilization defect (requires > 5 mM ammonium for growth) PMID:15819622 orf19.1614 MEP1 CAL0006337 Homozygous null wild-type filamentous growth PMID:15819622 orf19.1614 MEP1 CAL0006337 Heterozygous null Viable Barcode deletion set, fitness test (haploinsufficient phenotype assay) PMID:17604452 orf19.1616 FGR23 CAL0006341 Heterozygous null Filamentous growth abnormal Decreased filamentous growth (solid Spider medium); heterozygous transposon mutant allele PMID:12773383 orf19.1617 CAL0006342 Heterozygous null Filamentous growth abnormal Decreased filamentous growth (solid Spider medium); heterozygous transposon mutant allele PMID:12773383 orf19.1618 GFA1 CAL0006344 Homozygous null Inviable Glucosamine auxotroph PMID:9933591 orf19.1618 GFA1 CAL0006344 Point Hyphal growth abnormal Decreased hyphal growth PMID:15158264 orf19.1618 GFA1 CAL0006344 Point Cell wall abnormal Altered chitin content PMID:15158264 orf19.1618 GFA1 CAL0006344 Heterozygous null Viable PMID:15158264 orf19.1618 GFA1 CAL0006344 Point Viable S208A mutant, which lacks PKA phosphorylation site PMID:15158264 orf19.1618 GFA1 CAL0006344 Homozygous null Inviable Viability rescued by GlcNAc PMID:15158264 orf19.1618 GFA1 CAL0006344 Heterozygous null Hyphal growth abnormal Decreased germination (37 deg in various liquid media including Lee's and media with GlcNAc) PMID:15158264 orf19.1618 GFA1 CAL0006344 Point Hyphal growth abnormal Decreased germination, increased pseudohyphal growth (37 deg in various liquid media including Lee's, media with GlcNAc, media with serum); S208A mutant PMID:15158264 orf19.1618 GFA1 CAL0006344 Point Hyphal growth abnormal PMID:15158264 orf19.1618 GFA1 CAL0006344 Point Cell wall abnormal Decreased induction of chitin synthesis and decreased induction of enzyme activity at 37 deg PMID:15158264 orf19.1618 GFA1 CAL0006344 Heterozygous null Viable Barcode deletion set, fitness test (haploinsufficient phenotype assay) PMID:17604452 orf19.1619 CAL0006346 Heterozygous null Viable Barcode deletion set, fitness test (haploinsufficient phenotype assay) PMID:17604452 orf19.1621 GPA2 CAL0006364 Homozygous null Viable PMID:15302825|PMID:15673611 orf19.1621 GPA2 CAL0006364 Homozygous null Filamentous growth abnormal Decreased filamentous growth (embedded in agar) PMID:15302825 orf19.1621 GPA2 CAL0006364 Homozygous null Filamentous growth abnormal Decreased filamentation (solid FBS or Spider media), suppressed by dbcAMP (cAMP derivative) PMID:15302825 orf19.1621 GPA2 CAL0006364 Homozygous null Hyphal growth abnormal Decreased hyphal growth (liquid Spider media) PMID:15302825 orf19.1621 GPA2 CAL0006364 Activated Hyphal growth abnormal Delayed hyphal growth (liquid media + serum) PMID:15302825 orf19.1621 GPA2 CAL0006364 Homozygous null Wild-type hyphal growth Normal hyphal growth (liquid medium + serum) PMID:15302825 orf19.1621 GPA2 CAL0006364 Activated Filamentous growth abnormal Increased filamentous growth PMID:15302825 orf19.1621 GPA2 CAL0006364 Homozygous null Hyphal growth abnormal Blocked yeast-to-hyphae switch in Spider liquid medium, Lee's medium at pH 7, solid SLAD medium or in embedded conditions PMID:12477787 orf19.1621 GPA2 CAL0006364 Dominant negative Hyphal growth abnormal Abolished hyphal growth in solid SLAD medium, embedded conditions, liquid Spider and Lee pH 7 media PMID:12477787 orf19.1621 GPA2 CAL0006364 Heterozygous null Wild-type virulence Mouse intravenous infection PMID:15302825 orf19.1621 GPA2 CAL0006364 Homozygous null Wild-type virulence Mouse intravenous infection PMID:15302825 orf19.1621 GPA2 CAL0006364 Activated Virulence defect Decreased virulence, Q355L allele, mouse intravenous infection PMID:15302825 orf19.1621 GPA2 CAL0006364 Heterozygous null Viable PMID:15302825|PMID:15673611 orf19.1621 GPA2 CAL0006364 Activated Viable Q355L PMID:15673611 orf19.1621 GPA2 CAL0006364 Homozygous null Filamentous growth abnormal Defect in embedded hyphal growth is rescued by cAMP, in contrast to a different published gpa2 mutant PMID:15673611 orf19.1621 GPA2 CAL0006364 Homozygous null Pheromone response abnormal hypersensitive to alpha factor PMID:16987174 orf19.1622 CAL0006366 Heterozygous null Viable Barcode deletion set, fitness test (haploinsufficient phenotype assay) PMID:17604452 orf19.1623 CAP1 CAL0006368 Activated Drug susceptibility altered Increased resistance to cadmium, PMID:9922230 orf19.1623 CAP1 CAL0006368 Activated Drug susceptibility altered Increased resistance to 4-nitroquinoline-N-oxide PMID:9922230 orf19.1623 CAP1 CAL0006368 Activated Drug susceptibility altered Increased resistance to 1,10-phenanthroline PMID:9922230 orf19.1623 CAP1 CAL0006368 Activated Drug susceptibility altered Increased resistance to diamide PMID:9922230 orf19.1623 CAP1 CAL0006368 Activated Drug susceptibility altered Increased resistance to fluconazole PMID:9922230 orf19.1623 CAP1 CAL0006368 Activated Drug susceptibility altered Increased resistance to cerulenin PMID:9922230 orf19.1623 CAP1 CAL0006368 Activated Drug susceptibility altered Increased resistance to brefeldin A PMID:9922230 orf19.1623 CAP1 CAL0006368 Homozygous null Drug susceptibility altered Increased resistance to cadmium, PMID:9922230 orf19.1623 CAP1 CAL0006368 Homozygous null Drug susceptibility altered Increased resistance to 4-nitroquinoline-N-oxide PMID:9922230 orf19.1623 CAP1 CAL0006368 Homozygous null Drug susceptibility altered Increased resistance to 1,10-phenanthroline PMID:9922230 orf19.1623 CAP1 CAL0006368 Homozygous null Oxidative stress susceptibility altered Increased sensitivity to H2O2 PMID:9922230 orf19.1623 CAP1 CAL0006368 Activated Viable PMID:9922230 orf19.1623 CAP1 CAL0006368 Homozygous null Viable PMID:9922230|PMID:12684384 orf19.1623 CAP1 CAL0006368 Homozygous null wild-type fluconazole sensitivity PMID:9922230 orf19.1623 CAP1 CAL0006368 Homozygous null Oxidative stress susceptibility altered Increased sensitivity to hydrogen peroxide and cadmium PMID:12684384 orf19.1623 CAP1 CAL0006368 Homozygous null Abnormal response to host Increased sensitivity to human whole blood or neutrophils PMID:15813733 orf19.1623 CAP1 CAL0006368 Homozygous null Transcription regulation abnormal Defect in TSA1 induction in response to peroxide PMID:16102003 orf19.1623 CAP1 CAL0006368 Homozygous null Viable Insertion mutation, supplementary data PMID:15964282 orf19.1623 CAP1 CAL0006368 Homozygous null Wild-type biofilm formation Insertion mutation, supplementary data PMID:15964282 orf19.1623 CAP1 CAL0006368 Homozygous null Oxidative stress susceptibility altered Increased sensitivity to high- or low-dose peroxide stress PMID:16339080 orf19.1623 CAP1 CAL0006368 Homozygous null Transcription regulation abnormal Gene expression, microarray PMID:16545688 orf19.1626 CAL0006376 Heterozygous null Viable Barcode deletion set, fitness test (haploinsufficient phenotype assay) PMID:17604452 orf19.1628 LAP41 CAL0006379 Homozygous null Viable PMID:14663094 orf19.1628 LAP41 CAL0006379 Heterozygous null Viable Barcode deletion set, fitness test (haploinsufficient phenotype assay) PMID:17604452 orf19.1631 ERG6 CAL0006397 Homozygous null Drug susceptibility altered Increased resistance to nystatin PMID:9593144 orf19.1631 ERG6 CAL0006397 Homozygous null Plasma membrane abnormal Altered plasma membrane permeability PMID:9593144 orf19.1631 ERG6 CAL0006397 Homozygous null Plasma membrane abnormal Altered plasma membrane sterol content PMID:9593144 orf19.1631 ERG6 CAL0006397 Homozygous null Viable PMID:9593144 orf19.1631 ERG6 CAL0006397 Homozygous null Drug susceptibility altered Hypersensitivity to cyclosporin A (CsA) or FK506 PMID:11847103 orf19.1631 ERG6 CAL0006397 Heterozygous null Wild-type drug sensitivity Cyclosporin A (CsA), FK506 PMID:11847103 orf19.1631 ERG6 CAL0006397 Depletion Viable large-scale identification of essential genes by gene replacement and conditional expression (GRACE) method PMID:14507372 orf19.1631 ERG6 CAL0006397 Heterozygous null Viable Barcode deletion set, fitness test (haploinsufficient phenotype assay) PMID:17604452 orf19.1633 CAL0006401 Heterozygous null Viable Barcode deletion set, fitness test (haploinsufficient phenotype assay) PMID:17604452 orf19.1635 RPL12 CAL0006405 Heterozygous null Viable Barcode deletion set, fitness test (haploinsufficient phenotype assay) PMID:17604452 orf19.1637 CAL0006410 Heterozygous null Viable Barcode deletion set, fitness test (haploinsufficient phenotype assay) PMID:17604452 orf19.1639 CAL0006414 Heterozygous null Viable Barcode deletion set, fitness test (haploinsufficient phenotype assay) PMID:17604452 orf19.1641 CAL0000012 Heterozygous null Viable Barcode deletion set, fitness test (haploinsufficient phenotype assay) PMID:17604452 orf19.1646 CAL0000019 Heterozygous null Viable Barcode deletion set, fitness test (haploinsufficient phenotype assay) PMID:17604452 orf19.1648 RAD50 CAL0000021 Heterozygous null Viable Barcode deletion set, fitness test (haploinsufficient phenotype assay) PMID:17604452 orf19.1649 CAL0000022 Heterozygous null Viable Barcode deletion set, fitness test (haploinsufficient phenotype assay) PMID:17604452 orf19.1655 PXP2 CAL0000040 Heterozygous null Viable Barcode deletion set, fitness test (haploinsufficient phenotype assay) PMID:17604452 orf19.1659 ALG8 CAL0000044 Heterozygous null Viable Barcode deletion set, fitness test (haploinsufficient phenotype assay) PMID:17604452 orf19.166 CAL0003189 Heterozygous null Viable Barcode deletion set, fitness test (haploinsufficient phenotype assay) PMID:17604452 orf19.1661 CAL0000067 Heterozygous null Viable Barcode deletion set, fitness test (haploinsufficient phenotype assay) PMID:17604452 orf19.1663 MNT2 CAL0000069 Homozygous null Adhesion abnormal Decreased adhesion to Matrigel or to human buccal epithelial cells PMID:15519997 orf19.1663 MNT2 CAL0000069 Homozygous null Wild-type virulence Mouse intravenous infection; double mutant does show defect PMID:15519997 orf19.1663 MNT2 CAL0000069 Depletion Viable large-scale identification of essential genes by gene replacement and conditional expression (GRACE) method PMID:14507372 orf19.1663 MNT2 CAL0000069 Heterozygous null Viable Barcode deletion set, fitness test (haploinsufficient phenotype assay) PMID:17604452 orf19.1664 CAL0000070 Heterozygous null Viable Barcode deletion set, fitness test (haploinsufficient phenotype assay) PMID:17604452 orf19.1665 MNT1 CAL0000071 Homozygous null Adhesion abnormal Decreased adhesion (human buccal epithelial cells in vitro) PMID:9636208 orf19.1665 MNT1 CAL0000071 Homozygous null Cell wall abnormal Severely decreased cell wall O-linked oligosaccharide containing second or third mannose PMID:9636208 orf19.1665 MNT1 CAL0000071 Heterozygous null Viable Wild-type growth PMID:9636208 orf19.1665 MNT1 CAL0000071 Homozygous null Viable PMID:9636208 orf19.1665 MNT1 CAL0000071 Heterozygous null Virulence defect Decreased virulence in guinea pig systemic infection model PMID:9636208 orf19.1665 MNT1 CAL0000071 Heterozygous null Virulence defect Decreased virulence in mouse systemic infection model PMID:9636208 orf19.1665 MNT1 CAL0000071 Heterozygous null Virulence defect Decreased virulence in rat vaginal infection model PMID:9636208 orf19.1665 MNT1 CAL0000071 Homozygous null Virulence defect Slightly decreased tissue colonization (mouse intravenous infection) PMID:9636208 orf19.1665 MNT1 CAL0000071 Homozygous null Virulence defect Decreased tissue colonization (guinea pig intravenous infection) PMID:9636208 orf19.1665 MNT1 CAL0000071 Homozygous null Virulence defect Decreased virulence in guinea pig systemic infection model PMID:9636208 orf19.1665 MNT1 CAL0000071 Homozygous null Virulence defect Decreased virulence in mouse systemic infection model PMID:9636208 orf19.1665 MNT1 CAL0000071 Homozygous null Virulence defect Decreased virulence in rat vaginal infection model PMID:9636208 orf19.1665 MNT1 CAL0000071 Homozygous null Wild-type hyphal growth Normal germ tube induction (by serum, Spider media, or GlcNAc) PMID:9636208 orf19.1665 MNT1 CAL0000071 Homozygous null Adhesion abnormal Decreased adhesion to Matrigel or to human buccal epithelial cells PMID:15519997 orf19.1665 MNT1 CAL0000071 Homozygous null Wild-type virulence Mouse intravenous infection; double mutant does show defect PMID:15519997 orf19.1665 MNT1 CAL0000071 Homozygous null Protein activity abnormal decreased alpha-1,2-mannosyltransferase activity in membrane fraction PMID:9636208 orf19.1665 MNT1 CAL0000071 Heterozygous null Protein activity abnormal decreased alpha-1,2-mannosyltransferase activity in membrane fraction, intermediate phenotype PMID:9636208 orf19.1665 MNT1 CAL0000071 Heterozygous null Viable Barcode deletion set, fitness test (haploinsufficient phenotype assay) PMID:17604452 orf19.1667 CAL0000073 Heterozygous null Viable Barcode deletion set, fitness test (haploinsufficient phenotype assay) PMID:17604452 orf19.1669 AFG3 CAL0000075 Homozygous null Inviable PMID:12524333 orf19.1669 AFG3 CAL0000075 Heterozygous null Viable Barcode deletion set, fitness test (haploinsufficient phenotype assay) PMID:17604452 orf19.1670 BRO1 CAL0000103 Homozygous null Viable PMID:15371534|PMID:15590834 orf19.1670 BRO1 CAL0000103 Homozygous null Wild-type hyphal growth Normal hyphal growth (solid medium, alkaline pH) orf19.1670 BRO1 CAL0000103 Homozygous null Wild-type hyphal growth Normal hyphal growth (solid medium, alkaline pH) PMID:15371534 orf19.1670 BRO1 CAL0000103 Heterozygous null Viable PMID:15590834 orf19.1670 BRO1 CAL0000103 Homozygous null wild-type filamentous growth Normal filamentation (solid M199 medium, pH 8, or liquid media with serum) PMID:15590834 orf19.1670 BRO1 CAL0000103 Homozygous null Defect in multivesicular body (MVB) transport to the vacuole PMID:15590834 orf19.1671 UTR2 CAL0000104 Heterozygous null Adhesion abnormal Decreased adhesion, intermediate phenotype (human fadu oropharyngeal epithelial cells) PMID:15042589 orf19.1671 UTR2 CAL0000104 Homozygous null Adhesion abnormal Decreased adhesion (human fadu oropharyngeal epithelial cells) PMID:15042589 orf19.1671 UTR2 CAL0000104 Heterozygous null Drug susceptibility altered Increased sensitivity to SDS, intermediate phenotype PMID:15042589 orf19.1671 UTR2 CAL0000104 Homozygous null Drug susceptibility altered Increased sensitivity to SDS PMID:15042589 orf19.1671 UTR2 CAL0000104 Homozygous null Hyphal growth abnormal Abolished invasive hyphal growth (solid Spider media) PMID:15042589 orf19.1671 UTR2 CAL0000104 Homozygous null Viable Wild-type growth rate PMID:15042589 orf19.1671 UTR2 CAL0000104 Homozygous null Virulence defect Decreased kidney and brain colonization (mouse intravenous infection) PMID:15042589 orf19.1671 UTR2 CAL0000104 Homozygous null Virulence defect Decreased virulence in mouse systemic infection model PMID:15042589|PMID:17074760 orf19.1671 UTR2 CAL0000104 Homozygous null wild-type sensitivity to Calcofluor white PMID:15042589 orf19.1671 UTR2 CAL0000104 Homozygous null wild-type sensitivity to NaCl PMID:15042589 orf19.1671 UTR2 CAL0000104 Homozygous null Wild-type drug sensitivity fluconazole, amphotericin B, micafungin PMID:15042589 orf19.1671 UTR2 CAL0000104 Homozygous null Viable PMID:17074760 orf19.1671 UTR2 CAL0000104 Homozygous null increased sensitivity to congo red PMID:17074760 orf19.1672 CAL0000105 Heterozygous null Viable Barcode deletion set, fitness test (haploinsufficient phenotype assay) PMID:17604452 orf19.1673 PPT1 CAL0000106 Heterozygous null Viable Barcode deletion set, fitness test (haploinsufficient phenotype assay) PMID:17604452 orf19.1674 CAL0000107 Heterozygous null Viable Barcode deletion set, fitness test (haploinsufficient phenotype assay) PMID:17604452 orf19.1675 CAL0000108 Heterozygous null Viable Barcode deletion set, fitness test (haploinsufficient phenotype assay) PMID:17604452 orf19.1680 CAL0000146 Heterozygous null Viable Barcode deletion set, fitness test (haploinsufficient phenotype assay) PMID:17604452 orf19.1682 CAL0000148 Heterozygous null Viable Barcode deletion set, fitness test (haploinsufficient phenotype assay) PMID:17604452 orf19.1683 PPH21 CAL0000149 Heterozygous null Viable Barcode deletion set, fitness test (haploinsufficient phenotype assay) PMID:17604452 orf19.1686 CAL0000152 Heterozygous null Viable Barcode deletion set, fitness test (haploinsufficient phenotype assay) PMID:17604452 orf19.1687 CAL0000153 Heterozygous null Viable Barcode deletion set, fitness test (haploinsufficient phenotype assay) PMID:17604452 orf19.169 CHO2 CAL0003197 Heterozygous null Viable Barcode deletion set, fitness test (haploinsufficient phenotype assay) PMID:17604452 orf19.1693 CAS4 CAL0000189 Homozygous null (inferred) Inviable Deletion or insertion mutations at codons 836, 842, 1163, or 1828 appear to be lethal PMID:16552442 orf19.1693 CAS4 CAL0000189 Unknown/unspecified Viable Insertion mutation near 3' end PMID:16552442 orf19.1693 CAS4 CAL0000189 Unknown/unspecified Drug susceptibility altered Increase in caspofungin sensitivity (insertion mutation near 3' end) PMID:16552442 orf19.1693 CAS4 CAL0000189 Homozygous null Viable Insertion mutation, supplementary data PMID:15964282 orf19.1693 CAS4 CAL0000189 Homozygous null Wild-type biofilm formation Insertion mutation, supplementary data PMID:15964282 orf19.1694 CAL0000190 Homozygous null Viable Insertion mutation, supplementary data PMID:15964282 orf19.1694 CAL0000190 Homozygous null Wild-type biofilm formation Insertion mutation, supplementary data PMID:15964282 orf19.1698 CAL0000192 Heterozygous null Viable Barcode deletion set, fitness test (haploinsufficient phenotype assay) PMID:17604452 orf19.1699 BZZ1 CAL0000193 Homozygous null Viable PMID:17431925 orf19.1699 BZZ1 CAL0000193 Homozygous null Wild-type cell morphology no defects in polarized growth detected PMID:17431925 orf19.1699 BZZ1 CAL0000193 Heterozygous null Viable Barcode deletion set, fitness test (haploinsufficient phenotype assay) PMID:17604452 orf19.1701 CAL0000757 Heterozygous null Viable Barcode deletion set, fitness test (haploinsufficient phenotype assay) PMID:17604452 orf19.1709 CAL0000769 Heterozygous null Viable Barcode deletion set, fitness test (haploinsufficient phenotype assay) PMID:17604452 orf19.171 DBP2 CAL0003204 Heterozygous null Viable Barcode deletion set, fitness test (haploinsufficient phenotype assay) PMID:17604452 orf19.1710 CAL0000774 Heterozygous null Viable Barcode deletion set, fitness test (haploinsufficient phenotype assay) PMID:17604452 orf19.1711 END3 CAL0000775 Heterozygous null Viable Barcode deletion set, fitness test (haploinsufficient phenotype assay) PMID:17604452 orf19.1713 CAL0000777 Heterozygous null Viable Barcode deletion set, fitness test (haploinsufficient phenotype assay) PMID:17604452 orf19.1714 PGA44 CAL0000779 Homozygous null Viable PMID:17873081 orf19.1715 IRO1 CAL0000781 Heterozygous null Viable PMID:16237272 orf19.1715 IRO1 CAL0000781 Homozygous null Viable PMID:16237272 orf19.1715 IRO1 CAL0000781 Heterozygous null Abnormal iron utilization Growth is slowed upon iron chelation, whereas homozygous null mutant shows similar growth rate in the absence and presence of an iron chelator PMID:16237272 orf19.1715 IRO1 CAL0000781 Homozygous null Slow growth Slow growth compared to wild type (in absence or presence of iron chelator) PMID:16237272 orf19.1715 IRO1 CAL0000781 Heterozygous null Wild-type virulence Mouse intravenous infection PMID:16237272 orf19.1715 IRO1 CAL0000781 Homozygous null Virulence defect Decreased virulence; mouse intravenous infection PMID:16237272 orf19.1716 URA3 CAL0000783 Depletion Hyphal growth abnormal Decreased hyphal growth on solid medium (199 and Spider media); strains carrying URA3 expressed from an ectopic location PMID:14500538 orf19.1716 URA3 CAL0000783 Depletion Adhesion abnormal Decreased adhesion (human epithelial cells, buccal); strains carrying URA3 expressed from an ectopic location PMID:14500538 orf19.1716 URA3 CAL0000783 Depletion Virulence defect Decreased virulence in mouse systemic infection model; strains carrying URA3 expressed from an ectopic location PMID:14500538 orf19.1716 URA3 CAL0000783 Depletion Uridine auxotrophy PMID:10564518 orf19.1716 URA3 CAL0000783 Homozygous null Viable Mutant accumulates abundant orotic acid (visible as crystals in growth media) in the presence of acetate PMID:15502413 orf19.1716 URA3 CAL0000783 Homozygous null Viable PMID:3031459|PMID:11371541|PMID:8349105 orf19.1716 URA3 CAL0000783 Homozygous null Uridine auxotrophy Also 5-FOA resistant PMID:3031459|PMID:11371541 orf19.1716 URA3 CAL0000783 Homozygous null Adhesion abnormal Matrigel, human buccal epithelial cells PMID:11731143 orf19.1716 URA3 CAL0000783 Heterozygous null Wild-type adhesion Matrigel, human buccal epithelial cells PMID:11731143 orf19.1716 URA3 CAL0000783 Homozygous null Virulence defect Abolished migration across monolayer of intestinal epithelial cells (Caco-2) in absence of exogenous uridine PMID:10865906 orf19.1716 URA3 CAL0000783 Misexpression Virulence defect Variable expression due to the use of the ura-blaster gene disruption technique affects virulence in the mouse intravenous infection model PMID:9784536 orf19.1716 URA3 CAL0000783 Misexpression Filamentous growth abnormal Defect had originally been attributed to mutation of HWP1 PMID:15817775 orf19.1716 URA3 CAL0000783 Misexpression Virulence defect Mouse intravenous infection; defect had originally been attributed to mutation of HWP1 PMID:15817775 orf19.1716 URA3 CAL0000783 Misexpression Virulence defect URA3 influences virulence (mouse intravenous infection) PMID:12011025 orf19.1716 URA3 CAL0000783 Heterozygous null Viable PMID:3031459|PMID:8349105 orf19.1716 URA3 CAL0000783 Homozygous null Uridine auxotrophy PMID:1936958|PMID:8349105 orf19.1716 URA3 CAL0000783 Homozygous null Virulence defect Rat intraperitonal infection PMID:16835826 orf19.1716 URA3 CAL0000783 Unknown/unspecified Wild-type phenotypic switching Mutation does not eliminate white-opaque switching PMID:1569024 orf19.172 CAL0003206 Heterozygous null Viable Barcode deletion set, fitness test (haploinsufficient phenotype assay) PMID:17604452 orf19.1720 CAL0000801 Heterozygous null Viable Barcode deletion set, fitness test (haploinsufficient phenotype assay) PMID:17604452 orf19.1721 NCE103 CAL0000802 Homozygous null Inviable Increased concentration of CO2 (more than 0.5%) required for growth PMID:16303561 orf19.1721 NCE103 CAL0000802 Heterozygous null Viable Barcode deletion set, fitness test (haploinsufficient phenotype assay) PMID:17604452 orf19.1723 CAL0000804 Heterozygous null Viable Barcode deletion set, fitness test (haploinsufficient phenotype assay) PMID:17604452 orf19.1727 PMC1 CAL0000810 Homozygous null Viable PMID:12753189 orf19.1727 PMC1 CAL0000810 Homozygous null Drug susceptibility altered Increased resistance to fluconazole PMID:12753189 orf19.1727 PMC1 CAL0000810 Homozygous null Other stress susceptibility altered Increased sensitivity to calcium chloride PMID:12753189 orf19.1727 PMC1 CAL0000810 Homozygous null Other stress susceptibility altered Increased resistance to lithium chloride PMID:12753189 orf19.1727 PMC1 CAL0000810 Heterozygous null Viable Barcode deletion set, fitness test (haploinsufficient phenotype assay) PMID:17604452 orf19.1729 CAL0000814 Homozygous null Viable Insertion mutation, supplementary data PMID:15964282 orf19.1729 CAL0000814 Homozygous null Wild-type biofilm formation Insertion mutation, supplementary data PMID:15964282 orf19.173 CAL0003208 Homozygous null Viable Insertion mutation, supplementary data PMID:15964282 orf19.173 CAL0003208 Homozygous null Wild-type biofilm formation Insertion mutation, supplementary data PMID:15964282 orf19.1732 CAL0000829 Heterozygous null Viable Barcode deletion set, fitness test (haploinsufficient phenotype assay) PMID:17604452 orf19.1738 UGP1 CAL0000839 Heterozygous null Viable Barcode deletion set, fitness test (haploinsufficient phenotype assay) PMID:17604452 orf19.1741 CAL0000853 Heterozygous null Viable Barcode deletion set, fitness test (haploinsufficient phenotype assay) PMID:17604452 orf19.1742 HEM3 CAL0000854 Homozygous null Abnormal iron utilization Heme auxotrophy PMID:2671651 orf19.1742 HEM3 CAL0000854 Homozygous null Viable PMID:2671651 orf19.1742 HEM3 CAL0000854 Depletion Inviable large-scale identification of essential genes by gene replacement and conditional expression (GRACE) method PMID:14507372 orf19.1742 HEM3 CAL0000854 Heterozygous null Viable Barcode deletion set, fitness test (haploinsufficient phenotype assay) PMID:17604452 orf19.1747 KIP2 CAL0000859 Heterozygous null Viable Barcode deletion set, fitness test (haploinsufficient phenotype assay) PMID:17604452 orf19.1751 SPT23 CAL0000868 Conditional Fatty acid auxotrophy requirement for unsaturated fatty acids PMID:16415349 orf19.1753 PUS7 CAL0000869 Heterozygous null Viable Barcode deletion set, fitness test (haploinsufficient phenotype assay) PMID:17604452 orf19.1754 CAL0000870 Heterozygous null Viable Barcode deletion set, fitness test (haploinsufficient phenotype assay) PMID:17604452 orf19.1755 CAL0000871 Heterozygous null Viable Barcode deletion set, fitness test (haploinsufficient phenotype assay) PMID:17604452 orf19.1757 CAL0000873 Homozygous null Viable Insertion mutation, supplementary data PMID:15964282 orf19.1757 CAL0000873 Homozygous null Wild-type biofilm formation Insertion mutation, supplementary data PMID:15964282 orf19.1759 PHO23 CAL0000874 Homozygous null Viable PMID:14663094 orf19.1760 RAS1 CAL0000896 Activated decreased glycogen accumulation PMID:10515923 orf19.1760 RAS1 CAL0000896 Activated Heat sensitive PMID:10515923 orf19.1760 RAS1 CAL0000896 Overexpression Heat sensitive PMID:10515923 orf19.1760 RAS1 CAL0000896 Activated Hyphal growth abnormal Increased hyphal growth (solid media) PMID:10515923 orf19.1760 RAS1 CAL0000896 Dominant negative Hyphal growth abnormal Abolished hyphal growth (solid media) PMID:10515923 orf19.1760 RAS1 CAL0000896 Homozygous null Hyphal growth abnormal Abolished hyphal induction by serum (solid or liquid media) PMID:10515923 orf19.1760 RAS1 CAL0000896 Overexpression Hyphal growth abnormal Increased hyphal growth (solid media) PMID:10515923 orf19.1760 RAS1 CAL0000896 Homozygous null Slow growth PMID:10515923 orf19.1760 RAS1 CAL0000896 Activated Viable PMID:10515923 orf19.1760 RAS1 CAL0000896 Dominant negative Viable PMID:10515923 orf19.1760 RAS1 CAL0000896 Heterozygous null Viable PMID:10515923|PMID:11722734 orf19.1760 RAS1 CAL0000896 Homozygous null Viable PMID:10515923|PMID:11722734 orf19.1760 RAS1 CAL0000896 Overexpression Viable PMID:10515923 orf19.1760 RAS1 CAL0000896 Dominant negative wild-type glycogen accumulation PMID:10515923 orf19.1760 RAS1 CAL0000896 Homozygous null wild-type glycogen accumulation PMID:10515923 orf19.1760 RAS1 CAL0000896 Heterozygous null Wild-type hyphal growth Normal hyphal induction by serum (solid or liquid media) PMID:10515923 orf19.1760 RAS1 CAL0000896 Homozygous null Slow growth Rescued by cAMP, suppressed by Hst7p overproduction PMID:11722734 orf19.1760 RAS1 CAL0000896 Homozygous null Hyphal growth abnormal Mutant forms short pseudohyphae, no hyphae (all hyphal inducing conditions, except microaerophilic conditions, under which hyphae are observed) PMID:11722734 orf19.1760 RAS1 CAL0000896 Heterozygous null Hyphal growth abnormal Partial defect on solid media; wild-type hyphal growth on liquid media PMID:11722734 orf19.1760 RAS1 CAL0000896 Activated Hyphal growth abnormal Hyperfilamentation, suppressed by mutation of HST7, CPH1, EFG1, CDC35, or CPH1 and EFG1 PMID:11722734 orf19.1760 RAS1 CAL0000896 Homozygous null Transcription regulation abnormal Defect in serum induction of SAP4-6 and HWP1 PMID:11722734 orf19.1760 RAS1 CAL0000896 Homozygous null Hyphal growth abnormal Defect in hyphal growth in murine macrophage and defect in macrophage cell damage PMID:11722734 orf19.1760 RAS1 CAL0000896 Heterozygous null Wild-type virulence Mouse intravenous infection PMID:11722734 orf19.1760 RAS1 CAL0000896 Homozygous null Virulence defect Mouse intravenous infection; virulence defect suppressed by Hst7p overproduction PMID:11722734 orf19.1760 RAS1 CAL0000896 Homozygous null defect in regulation of cAMP levels Abolished cAMP response to hyphal induction by glucose and serum PMID:15673611 orf19.1760 RAS1 CAL0000896 Homozygous null Transcription regulation abnormal Yeast-form and hyphal transcription profiles evaluated PMID:15269278 orf19.1760 RAS1 CAL0000896 Homozygous null Heat stress susceptibility altered Slightly increased resistance to heat shock PMID:15269278 orf19.1760 RAS1 CAL0000896 Homozygous null Apoptosis response abnormal Increased resistance to apoptosis-inducing stimuli PMID:16407097 orf19.1760 RAS1 CAL0000896 Activated Apoptosis response abnormal RAS1(Val13) mutant is hypersensitive to apoptosis-inducing stimuli PMID:16407097 orf19.1760 RAS1 CAL0000896 Activated Viable Inducible RAS1(Val13) activated mutation PMID:16407097 orf19.1760 RAS1 CAL0000896 Activated Colony morphology abnormal Wrinkly colonies; RAS1-Val13 mutation PMID:16407097 orf19.1760 RAS1 CAL0000896 Homozygous null Virulence defect Moderately decreased virulence in a Galleria mellonella (Greater Wax Moth) larval model PMID:12381467 orf19.1760 RAS1 CAL0000896 Dominant negative wild-type heat sensitivity wild-type heat shock sensitivity PMID:10515923 orf19.1760 RAS1 CAL0000896 Heterozygous null Viable Barcode deletion set, fitness test (haploinsufficient phenotype assay) PMID:17604452 orf19.1761 CAL0000897 Heterozygous null Viable Barcode deletion set, fitness test (haploinsufficient phenotype assay) PMID:17604452 orf19.1762 CAL0000898 Homozygous null Viable PMID:14663094 orf19.1769 CAL0000905 Heterozygous null Viable Barcode deletion set, fitness test (haploinsufficient phenotype assay) PMID:17604452 orf19.1771 CAL0000928 Heterozygous null Viable Barcode deletion set, fitness test (haploinsufficient phenotype assay) PMID:17604452 orf19.1773 RAP1 CAL0000930 antisense expression Cell aggregation cell aggregation at stationary phase PMID:14745778 orf19.1773 RAP1 CAL0000930 Homozygous null Viable PMID:12706897 orf19.1773 RAP1 CAL0000930 Homozygous null Filamentous growth abnormal increased pseudohyphal growth PMID:12706897 orf19.1773 RAP1 CAL0000930 Homozygous null Wild-type hyphal growth Normal hyphal growth (various solid media or liquid media, except in liquid RPMI + serum) PMID:12706897 orf19.1773 RAP1 CAL0000930 Homozygous null Hyphal growth abnormal Slightly decreased hyphal growth (liquid RPMI + serum) PMID:12706897 orf19.1774 CAL0000931 Heterozygous null Viable Barcode deletion set, fitness test (haploinsufficient phenotype assay) PMID:17604452 orf19.1776 CAL0000933 Heterozygous null Viable Barcode deletion set, fitness test (haploinsufficient phenotype assay) PMID:17604452 orf19.1777 CAL0000934 Heterozygous null Viable Barcode deletion set, fitness test (haploinsufficient phenotype assay) PMID:17604452 orf19.1779 MP65 CAL0000936 Homozygous null Viable PMID:17217426 orf19.1779 MP65 CAL0000936 Homozygous null Hyphal growth abnormal severely impaired hyphal differentiation PMID:17217426 orf19.1779 MP65 CAL0000936 Homozygous null Adhesion abnormal defective in adherence to plastic PMID:17217426 orf19.1779 MP65 CAL0000936 Homozygous null Virulence defect decreased virulence in mouse model of haematogenously disseminated candidiasis PMID:17217426 orf19.1789.1 LYS1 CAL0006591 Unknown/unspecified Lysine auxotrophy PMID:1429460 orf19.1789.1 LYS1 CAL0006591 Unknown/unspecified Viable PMID:1429460 orf19.1789.1 LYS1 CAL0006591 Point Protein activity abnormal Site-directed mutagenesis study, defining residues involved in catalysis of accharopine dehydrogenase (forward) reaction and reverse reaction PMID:16292576 orf19.1791 CAL0000994 Heterozygous null Viable Barcode deletion set, fitness test (haploinsufficient phenotype assay) PMID:17604452 orf19.1792 CAL0000995 Heterozygous null Viable Barcode deletion set, fitness test (haploinsufficient phenotype assay) PMID:17604452 orf19.1793 CAL0000996 Homozygous null Viable PMID:14663094 orf19.1793 CAL0000996 Heterozygous null Viable Barcode deletion set, fitness test (haploinsufficient phenotype assay) PMID:17604452 orf19.1795 PUF3 CAL0000998 Homozygous null Viable PMID:14663094 orf19.1795 PUF3 CAL0000998 Heterozygous null Viable Barcode deletion set, fitness test (haploinsufficient phenotype assay) PMID:17604452 orf19.1797 CAL0001000 Heterozygous null Viable Barcode deletion set, fitness test (haploinsufficient phenotype assay) PMID:17604452 orf19.1798 CAL0001001 Homozygous null Viable PMID:14663094 orf19.1799 CAL0001002 Heterozygous null Viable Barcode deletion set, fitness test (haploinsufficient phenotype assay) PMID:17604452 orf19.18 IMH3 CAL0000509 Overexpression Drug susceptibility altered Increased resistance to mycophenolic acid PMID:15034753|PMID:9079920 orf19.18 IMH3 CAL0000509 Overexpression Viable PMID:9079920 orf19.18 IMH3 CAL0000509 Multiple Drug susceptibility altered Increased resistance to mycophenolic acid; resistance allele has I47V, S102A, G482D mutations PMID:11119495 orf19.18 IMH3 CAL0000509 Point Drug susceptibility altered A251T mutation causes increased resistance to mycophenolic acid and increased sensitivity to mizoribine monophosphate PMID:15665003 orf19.18 IMH3 CAL0000509 Heterozygous null Drug susceptibility altered Increased sensitivity to mizoribine PMID:15665003 orf19.18 IMH3 CAL0000509 Heterozygous null Viable PMID:15665003 orf19.1800 CAL0001572 Heterozygous null Viable Barcode deletion set, fitness test (haploinsufficient phenotype assay) PMID:17604452 orf19.1801 CAL0001574 Heterozygous null Viable Barcode deletion set, fitness test (haploinsufficient phenotype assay) PMID:17604452 orf19.1803 CDC43 CAL0001576 Homozygous null Viable growth at late log phase reduced to 70% of wild type PMID:10633104 orf19.1803 CDC43 CAL0001576 Homozygous null Slow growth PMID:10633104 orf19.1803 CDC43 CAL0001576 Homozygous null Cell morphology abnormal round, swollen and clumped cells with significantly fewer buds PMID:10633104 orf19.1803 CDC43 CAL0001576 Depletion Viable large-scale identification of essential genes by gene replacement and conditional expression (GRACE) method PMID:14507372 orf19.1803 CDC43 CAL0001576 Heterozygous null Viable Barcode deletion set, fitness test (haploinsufficient phenotype assay) PMID:17604452 orf19.1804 CAL0001578 Heterozygous null Viable Barcode deletion set, fitness test (haploinsufficient phenotype assay) PMID:17604452 orf19.1805 PEX14 CAL0001580 Homozygous null Viable PMID:14663094 orf19.1805 PEX14 CAL0001580 Heterozygous null Viable Barcode deletion set, fitness test (haploinsufficient phenotype assay) PMID:17604452 orf19.1809 CAL0001586 Heterozygous null Viable Barcode deletion set, fitness test (haploinsufficient phenotype assay) PMID:17604452 orf19.1814 CAL0001601 Heterozygous null Viable Barcode deletion set, fitness test (haploinsufficient phenotype assay) PMID:17604452 orf19.1815 CAL0001603 Heterozygous null Viable Barcode deletion set, fitness test (haploinsufficient phenotype assay) PMID:17604452 orf19.1816 ALS3 CAL0001605 Homozygous null Adhesion abnormal Decreased adhesion (human umbilical vein endothelial cells and buccal epithelial cells) PMID:15256583 orf19.1816 ALS3 CAL0001605 Homozygous null Virulence defect Decreased virulence in an in vitro model of oral infection (buccal reconstituted human epithelium) PMID:15256583 orf19.1816 ALS3 CAL0001605 Homozygous null Wild-type hyphal growth Normal germ tube formation (RPMI or Lee medium} PMID:15256583 orf19.1816 ALS3 CAL0001605 Heterozygous null Adhesion abnormal Allele-specific effect on adhesion; mutant with only the large ALS3 allele shows wild-type adhesion and mutant with only the small ALS3 allele shows an adhesion defect (pharyngeal epithelial cells or human umbilical vein endothelial cells) PMID:15758214 orf19.1816 ALS3 CAL0001605 Homozygous null Adhesion abnormal Homozygous null mutant adhesion defect is more severe than that of either heterozygous null mutant (pharyngeal epithelial cells or human umbilical vein endothelial cells) PMID:15758214 orf19.1816 ALS3 CAL0001605 Homozygous null Biofilm formation abnormal PMID:16839200 orf19.1816 ALS3 CAL0001605 Homozygous null Biofilm formation abnormal disorganized and weakened biofilm structure on silicone elastomer surfaces PMID:16849795 orf19.1816 ALS3 CAL0001605 Homozygous null Adhesion abnormal Decreased association with human umbilical vein endothelial cells (HUVEC) and decreased endocytosis by HUVEC and oral epithelial (FaDu) cells PMID:17311474 orf19.1822 CAL0001625 Homozygous null (inferred) Inviable Insertion mutation, supplementary data PMID:15964282 orf19.1825 CAL0001629 Homozygous null Viable PMID:14663094 orf19.1826 MDM34 CAL0001630 Homozygous null Viable Insertion mutation, supplementary data PMID:15964282 orf19.1826 MDM34 CAL0001630 Homozygous null Wild-type biofilm formation Insertion mutation, supplementary data PMID:15964282 orf19.1826 MDM34 CAL0001630 Heterozygous null Viable Barcode deletion set, fitness test (haploinsufficient phenotype assay) PMID:17604452 orf19.1828 BUD16 CAL0001634 Heterozygous null Viable Barcode deletion set, fitness test (haploinsufficient phenotype assay) PMID:17604452 orf19.183 HIS3 CAL0003242 Heterozygous null Viable Barcode deletion set, fitness test (haploinsufficient phenotype assay) PMID:17604452 orf19.1832 FCY23 CAL0001652 Heterozygous null Viable Barcode deletion set, fitness test (haploinsufficient phenotype assay) PMID:17604452 orf19.1833 CAL0001653 Heterozygous null Viable Barcode deletion set, fitness test (haploinsufficient phenotype assay) PMID:17604452 orf19.1836 APN2 CAL0001657 Heterozygous null Viable Barcode deletion set, fitness test (haploinsufficient phenotype assay) PMID:17604452 orf19.1837 TBP1 CAL0001658 Heterozygous null Viable Barcode deletion set, fitness test (haploinsufficient phenotype assay) PMID:17604452 orf19.1839 RPA190 CAL0001661 Heterozygous null Viable Barcode deletion set, fitness test (haploinsufficient phenotype assay) PMID:17604452 orf19.1844 CAL0001677 Heterozygous null Viable Barcode deletion set, fitness test (haploinsufficient phenotype assay) PMID:17604452 orf19.1847 ARO10 CAL0001679 Heterozygous null Viable Barcode deletion set, fitness test (haploinsufficient phenotype assay) PMID:17604452 orf19.1853 HHT2 CAL0001692 Heterozygous null Viable Barcode deletion set, fitness test (haploinsufficient phenotype assay) PMID:17604452 orf19.1854 HHF22 CAL0001693 Heterozygous null Viable Barcode deletion set, fitness test (haploinsufficient phenotype assay) PMID:17604452 orf19.1857 CAL0001696 Homozygous null Viable PMID:14663094 orf19.1857 CAL0001696 Heterozygous null Viable Barcode deletion set, fitness test (haploinsufficient phenotype assay) PMID:17604452 orf19.1865 CAL0001732 Heterozygous null Viable Barcode deletion set, fitness test (haploinsufficient phenotype assay) PMID:17604452 orf19.1871 CAL0001763 Heterozygous null Viable Barcode deletion set, fitness test (haploinsufficient phenotype assay) PMID:17604452 orf19.1875 CAL0001767 Heterozygous null Viable Barcode deletion set, fitness test (haploinsufficient phenotype assay) PMID:17604452 orf19.1876 CAL0001768 Heterozygous null Viable Barcode deletion set, fitness test (haploinsufficient phenotype assay) PMID:17604452 orf19.1878 CAL0001770 Heterozygous null Viable Barcode deletion set, fitness test (haploinsufficient phenotype assay) PMID:17604452 orf19.188 CAL0003257 Heterozygous null Viable Barcode deletion set, fitness test (haploinsufficient phenotype assay) PMID:17604452 orf19.1880 HEM15 CAL0001790 Heterozygous null Viable Barcode deletion set, fitness test (haploinsufficient phenotype assay) PMID:17604452 orf19.1881 CAL0001792 Heterozygous null Viable Barcode deletion set, fitness test (haploinsufficient phenotype assay) PMID:17604452 orf19.1883 CAL0001793 Heterozygous null Viable Barcode deletion set, fitness test (haploinsufficient phenotype assay) PMID:17604452 orf19.1885 CAL0001794 Heterozygous null Viable Barcode deletion set, fitness test (haploinsufficient phenotype assay) PMID:17604452 orf19.1886 RCL1 CAL0001795 Depletion Inviable Repressible MET3 promoter-based expression PMID:16607011 orf19.1886 RCL1 CAL0001795 Homozygous null (inferred) Inviable PMID:16607011 orf19.1886 RCL1 CAL0001795 Heterozygous null Viable PMID:16607011 orf19.1886 RCL1 CAL0001795 Heterozygous null Viable Barcode deletion set, fitness test (haploinsufficient phenotype assay) PMID:17604452 orf19.1887 CAL0001796 Heterozygous null Viable Barcode deletion set, fitness test (haploinsufficient phenotype assay) PMID:17604452 orf19.1888 CAL0001797 Heterozygous null Viable Barcode deletion set, fitness test (haploinsufficient phenotype assay) PMID:17604452 orf19.1890 CAL0001823 Heterozygous null Viable Barcode deletion set, fitness test (haploinsufficient phenotype assay) PMID:17604452 orf19.1891 APR1 CAL0001825 Heterozygous null Viable Barcode deletion set, fitness test (haploinsufficient phenotype assay) PMID:17604452 orf19.1896 SSC1 CAL0001828 Heterozygous null Viable Barcode deletion set, fitness test (haploinsufficient phenotype assay) PMID:17604452 orf19.19 CAL0000510 Heterozygous null Viable Barcode deletion set, fitness test (haploinsufficient phenotype assay) PMID:17604452 orf19.1900 CAL0002493 Heterozygous null Viable Barcode deletion set, fitness test (haploinsufficient phenotype assay) PMID:17604452 orf19.1901 CAL0002494 Heterozygous null Viable Barcode deletion set, fitness test (haploinsufficient phenotype assay) PMID:17604452 orf19.1902 CAL0002495 Heterozygous null Viable Barcode deletion set, fitness test (haploinsufficient phenotype assay) PMID:17604452 orf19.1903 CAL0002496 Heterozygous null Viable TOR1-1/TOR1 and TOR1-2/TOR1 PMID:11600372 orf19.1903 CAL0002496 Heterozygous null Drug susceptibility altered Increased resistance to rapamycin; TOR1-1/TOR1 and TOR1-2/TOR1 PMID:11600372 orf19.1907 EMC9 CAL0002503 Homozygous null Viable PMID:14663094 orf19.1911 PGA52 CAL0002515 Heterozygous null Viable Barcode deletion set, fitness test (haploinsufficient phenotype assay) PMID:17604452 orf19.1915 MPP10 CAL0002520 Heterozygous null Viable Barcode deletion set, fitness test (haploinsufficient phenotype assay) PMID:17604452 orf19.1923 RRN3 CAL0002535 Heterozygous null Viable Barcode deletion set, fitness test (haploinsufficient phenotype assay) PMID:17604452 orf19.1934 CAL0002561 Heterozygous null Viable Barcode deletion set, fitness test (haploinsufficient phenotype assay) PMID:17604452 orf19.1936 SNF1 CAL0002564 Heterozygous null Slow growth PMID:9560244 orf19.1936 SNF1 CAL0002564 Homozygous null (inferred) Inviable Strain construction failed PMID:9560244 orf19.1936 SNF1 CAL0002564 Heterozygous null Filamentous growth abnormal increased filamentous growth PMID:9560244 orf19.1936 SNF1 CAL0002564 Heterozygous null Wild-type virulence Mouse intravenous infection PMID:9560244 orf19.1939 CAL0002569 Heterozygous null Viable Barcode deletion set, fitness test (haploinsufficient phenotype assay) PMID:17604452 orf19.1940 CAL0002581 Heterozygous null Viable Barcode deletion set, fitness test (haploinsufficient phenotype assay) PMID:17604452 orf19.1941 CAL0002582 Heterozygous null Viable Barcode deletion set, fitness test (haploinsufficient phenotype assay) PMID:17604452 orf19.1942 SGE1 CAL0002583 Heterozygous null Viable Barcode deletion set, fitness test (haploinsufficient phenotype assay) PMID:17604452 orf19.1944 GPR1 CAL0002585 Homozygous null Filamentous growth abnormal Decreased filamentation (solid FBS or Spider media), suppressed by dbcAMP (cAMP derivative) PMID:15302825 orf19.1944 GPR1 CAL0002585 Homozygous null Filamentous growth abnormal Decreased filamentous growth (embedded in agar) PMID:15302825 orf19.1944 GPR1 CAL0002585 Homozygous null Wild-type hyphal growth Normal hyphal growth (liquid medium + serum) PMID:15302825 orf19.1944 GPR1 CAL0002585 Homozygous null Viable PMID:15302825|PMID:15673611 orf19.1944 GPR1 CAL0002585 Homozygous null Hyphal growth abnormal Slightly decreased hyphal growth (liquid Spider media) PMID:15302825 orf19.1944 GPR1 CAL0002585 Overexpression Filamentous growth abnormal Increased filamentous growth PMID:15302825 orf19.1944 GPR1 CAL0002585 Homozygous null Filamentous growth abnormal Abolished filamentation by cells embedded in rich media PMID:15714240 orf19.1944 GPR1 CAL0002585 Unknown/unspecified Hyphal growth abnormal Defect in hyphal induction in response to low glucose (also fructose, maltose, sucrose or galactose) in minimal medium + methionine; homozygous gpr1D mutant PMID:15667329 orf19.1944 GPR1 CAL0002585 Heterozygous null Wild-type virulence Mouse intravenous infection PMID:15302825|PMID:15673611 orf19.1944 GPR1 CAL0002585 Homozygous null Wild-type virulence Mouse intravenous infection PMID:15302825 orf19.1944 GPR1 CAL0002585 Heterozygous null Viable PMID:15302825|PMID:15673611 orf19.1944 GPR1 CAL0002585 Homozygous null Filamentous growth abnormal Decreased filamentous growth (liquid Spider; solid serum, Spider, SLAD, or Lee media; growth embedded in agar; proline or methionine-induced filamentation; or filamentation in a reconstructed human skin model or systemic mouse infection model) PMID:15673611 orf19.1944 GPR1 CAL0002585 Homozygous null Virulence defect Decreased virulence (mouse intravenous infection) PMID:15673611 orf19.1944 GPR1 CAL0002585 Homozygous null defect in regulation of cAMP levels Decreased basal cAMP, but wild-type cAMP response to hyphal induction by glucose and serum PMID:15673611 orf19.1945 AUR1 CAL0002586 Heterozygous null Viable Barcode deletion set, fitness test (haploinsufficient phenotype assay) PMID:17604452 orf19.1946 CAL0002587 Heterozygous null Viable Barcode deletion set, fitness test (haploinsufficient phenotype assay) PMID:17604452 orf19.1949 VPS1 CAL0002589 Heterozygous null Viable Barcode deletion set, fitness test (haploinsufficient phenotype assay) PMID:17604452 orf19.1950 CAL0002596 Heterozygous null Viable Barcode deletion set, fitness test (haploinsufficient phenotype assay) PMID:17604452 orf19.1952 CAL0002598 Homozygous null Viable PMID:14663094 orf19.1953 CAL0002599 Heterozygous null Viable Barcode deletion set, fitness test (haploinsufficient phenotype assay) PMID:17604452 orf19.1954 PUS4 CAL0002600 Heterozygous null Viable Barcode deletion set, fitness test (haploinsufficient phenotype assay) PMID:17604452 orf19.1957 CYC3 CAL0002603 Homozygous null Carbon source utilization defect Abolished lactate utilization as carbon source PMID:9786186 orf19.1957 CYC3 CAL0002603 Homozygous null Hyphal growth abnormal Decreased germ tube formation (lee's medium) PMID:9786186 orf19.1957 CYC3 CAL0002603 Homozygous null Slow growth PMID:9786186 orf19.1957 CYC3 CAL0002603 Heterozygous null Viable Wild-type growth rate PMID:9786186 orf19.1957 CYC3 CAL0002603 Homozygous null Viable PMID:9786186 orf19.1957 CYC3 CAL0002603 Heterozygous null Viable Barcode deletion set, fitness test (haploinsufficient phenotype assay) PMID:17604452 orf19.1960 CLN3 CAL0002632 Homozygous null Inviable PMID:12524333 orf19.1960 CLN3 CAL0002632 Depletion Abolished budding Cells do not bud; they become enlarged and then begin filamentous growth (hyphae or pseudohyphae) PMID:15643064 orf19.1960 CLN3 CAL0002632 Depletion Hyphal growth abnormal Hyphal morphology is abnormal (liquid media with serum or pH 7.0, 37 deg) PMID:15643064 orf19.1960 CLN3 CAL0002632 Homozygous null (inferred) Inviable Construction of a homozygous null mutant was unsuccessful PMID:15643064 orf19.1960 CLN3 CAL0002632 Depletion Abolished budding Cells become enlarged and then begin filamentous growth PMID:15643065 orf19.1960 CLN3 CAL0002632 Depletion Hyphal growth abnormal Abnormal morphology of environmentally induced hyphae PMID:15643065 orf19.1960 CLN3 CAL0002632 Heterozygous null Viable Barcode deletion set, fitness test (haploinsufficient phenotype assay) PMID:17604452 orf19.1966 CAL0002637 Heterozygous null Viable Barcode deletion set, fitness test (haploinsufficient phenotype assay) PMID:17604452 orf19.1973 HAP5 CAL0002670 Heterozygous null Viable PMID:16215174 orf19.1973 HAP5 CAL0002670 Homozygous null Viable PMID:16215174 orf19.1973 HAP5 CAL0002670 Homozygous null Slow growth PMID:16215174 orf19.1973 HAP5 CAL0002670 Homozygous null Filamentous growth abnormal Decreased filamentation on solid serum, Spider, Lee, and liquid Spider; hyperfilamentation on solid alkaline M199 medium, poor carbon sources; wild-type filamentation in other liquid media PMID:16215174 orf19.1973 HAP5 CAL0002670 Homozygous null Hyphal growth abnormal PMID:16215174 orf19.1973 HAP5 CAL0002670 Homozygous null Transcription regulation abnormal COX5, CYC1, altered band shift of CCAAT site oligos in cell extracts PMID:16215174 orf19.1973 HAP5 CAL0002670 Heterozygous null Viable Barcode deletion set, fitness test (haploinsufficient phenotype assay) PMID:17604452 orf19.1975 CAL0002672 Heterozygous null Viable Barcode deletion set, fitness test (haploinsufficient phenotype assay) PMID:17604452 orf19.1977 CAL0002674 Heterozygous null Viable Barcode deletion set, fitness test (haploinsufficient phenotype assay) PMID:17604452 orf19.1978 GIT2 CAL0002675 Heterozygous null Viable Barcode deletion set, fitness test (haploinsufficient phenotype assay) PMID:17604452 orf19.1979 GIT1 CAL0002676 Heterozygous null Viable Barcode deletion set, fitness test (haploinsufficient phenotype assay) PMID:17604452 orf19.1980 GIT4 CAL0002702 Heterozygous null Viable Barcode deletion set, fitness test (haploinsufficient phenotype assay) PMID:17604452 orf19.1984 CAL0002706 Heterozygous null Viable Barcode deletion set, fitness test (haploinsufficient phenotype assay) PMID:17604452 orf19.1986 ARO2 CAL0002708 Heterozygous null Viable Barcode deletion set, fitness test (haploinsufficient phenotype assay) PMID:17604452 orf19.1988 CDC45 CAL0002709 Heterozygous null Viable Barcode deletion set, fitness test (haploinsufficient phenotype assay) PMID:17604452 orf19.1989 DCW1 CAL0002710 Homozygous null Viable Wild-type filamentous growth PMID:12912894 orf19.1989 DCW1 CAL0002710 Heterozygous null Viable Barcode deletion set, fitness test (haploinsufficient phenotype assay) PMID:17604452 orf19.1990 SNX4 CAL0002737 Heterozygous null Viable Barcode deletion set, fitness test (haploinsufficient phenotype assay) PMID:17604452 orf19.1991 CAL0002738 Heterozygous null Viable Barcode deletion set, fitness test (haploinsufficient phenotype assay) PMID:17604452 orf19.1992 SIR2 CAL0002739 Depletion Filamentous growth abnormal Increased filamentous growth (liquid or solid rich medium) PMID:10228170 orf19.1992 SIR2 CAL0002739 Overexpression Slow growth Slightly decreased growth PMID:10228170 orf19.1992 SIR2 CAL0002739 Homozygous null Phenotypic switching abnormal Greatly increased frequency of switching among variant colony morphologies (strain background) PMID:10228170 orf19.1992 SIR2 CAL0002739 Depletion Phenotypic switching abnormal Greatly increased frequency of switching among variant colony morphologies (strain background) PMID:10228170 orf19.1992 SIR2 CAL0002739 Homozygous null Karyotype abnormal Formation of an ribosomal DNA (rDNA) minichromosome PMID:10228170 orf19.1995 CAL0002742 Heterozygous null Viable Barcode deletion set, fitness test (haploinsufficient phenotype assay) PMID:17604452 orf19.1996 CHA1 CAL0002743 Heterozygous null Viable Heterozygous transposon mutant allele PMID:12773383 orf19.1996 CHA1 CAL0002743 Heterozygous null Viable Barcode deletion set, fitness test (haploinsufficient phenotype assay) PMID:17604452 orf19.20 RTS1 CAL0000518 Heterozygous null Viable Barcode deletion set, fitness test (haploinsufficient phenotype assay) PMID:17604452 orf19.2000 CAL0004313 Heterozygous null Viable Barcode deletion set, fitness test (haploinsufficient phenotype assay) PMID:17604452 orf19.2002 CAL0004316 Heterozygous null Viable Barcode deletion set, fitness test (haploinsufficient phenotype assay) PMID:17604452 orf19.2003 HNM1 CAL0004318 Heterozygous null Viable Barcode deletion set, fitness test (haploinsufficient phenotype assay) PMID:17604452 orf19.2005 REG1 CAL0004320 Heterozygous null Viable Barcode deletion set, fitness test (haploinsufficient phenotype assay) PMID:17604452 orf19.2007 CAL0004322 Heterozygous null Viable Barcode deletion set, fitness test (haploinsufficient phenotype assay) PMID:17604452 orf19.2012 NOT3 CAL0004330 Homozygous null Viable Wild-type growth rate (liquid YPD 37 deg) PMID:14500538 orf19.2012 NOT3 CAL0004330 Homozygous null Wild-type virulence Wild-type virulence in mouse systemic infection model PMID:14500538 orf19.2012 NOT3 CAL0004330 Homozygous null Hyphal growth abnormal Reduced filamentation ratio of colonies on solid medium 199 or Spider medium PMID:14500538 orf19.2012 NOT3 CAL0004330 Homozygous null Wild-type adhesion Wild-type adhesion (human epithelial cells, buccal) PMID:14500538 orf19.2013 KAR2 CAL0004332 Heterozygous null Viable Barcode deletion set, fitness test (haploinsufficient phenotype assay) PMID:17604452 orf19.2014 BCY1 CAL0004334 Homozygous null Inviable PMID:12524333|PMID:14871949 orf19.2014 BCY1 CAL0004334 Heterozygous null Viable PMID:14871949 orf19.2014 BCY1 CAL0004334 Overexpression Hyphal growth abnormal Decreased hyphal growth; decreased germ tube formation and filamentation (solid and liquid media or embedded in agar) PMID:14523129 orf19.2014 BCY1 CAL0004334 Heterozygous null Hyphal growth abnormal GlcNAc liquid media, Lee liquid media PMID:16473139 orf19.2014 BCY1 CAL0004334 Heterozygous null Viable Barcode deletion set, fitness test (haploinsufficient phenotype assay) PMID:17604452 orf19.2016 CAL0004337 Heterozygous null Viable Barcode deletion set, fitness test (haploinsufficient phenotype assay) PMID:17604452 orf19.2017 CAL0004338 Heterozygous null Viable Barcode deletion set, fitness test (haploinsufficient phenotype assay) PMID:17604452 orf19.2019 CAL0004340 Heterozygous null Viable Barcode deletion set, fitness test (haploinsufficient phenotype assay) PMID:17604452 orf19.202 CAL0003868 Heterozygous null Viable Barcode deletion set, fitness test (haploinsufficient phenotype assay) PMID:17604452 orf19.2020 HGT6 CAL0004351 Heterozygous null Viable Barcode deletion set, fitness test (haploinsufficient phenotype assay) PMID:17604452 orf19.2022 CAL0004356 Heterozygous null Viable Barcode deletion set, fitness test (haploinsufficient phenotype assay) PMID:17604452 orf19.2023 HGT7 CAL0004358 Heterozygous null Viable Barcode deletion set, fitness test (haploinsufficient phenotype assay) PMID:17604452 orf19.2026 CAL0004364 Heterozygous null Viable Barcode deletion set, fitness test (haploinsufficient phenotype assay) PMID:17604452 orf19.2028 MXR1 CAL0004365 Heterozygous null Viable Barcode deletion set, fitness test (haploinsufficient phenotype assay) PMID:17604452 orf19.2029 CAL0004366 Heterozygous null Viable Barcode deletion set, fitness test (haploinsufficient phenotype assay) PMID:17604452 orf19.2031 VPS24 CAL0004377 Homozygous null Viable PMID:15371534 orf19.2031 VPS24 CAL0004377 Homozygous null Wild-type hyphal growth Normal hyphal growth (solid medium, alkaline pH) PMID:15371534 orf19.2031 VPS24 CAL0004377 Heterozygous null Viable Barcode deletion set, fitness test (haploinsufficient phenotype assay) PMID:17604452 orf19.2033 PGA19 CAL0004383 Homozygous null Viable PMID:14663094 orf19.2036 CAL0004389 Heterozygous null Viable Barcode deletion set, fitness test (haploinsufficient phenotype assay) PMID:17604452 orf19.2039 CAL0004392 Heterozygous null Viable Barcode deletion set, fitness test (haploinsufficient phenotype assay) PMID:17604452 orf19.2040 CAL0004403 Heterozygous null Viable Barcode deletion set, fitness test (haploinsufficient phenotype assay) PMID:17604452 orf19.2041 CAL0004406 Heterozygous null Viable Barcode deletion set, fitness test (haploinsufficient phenotype assay) PMID:17604452 orf19.2043 CAL0004410 Heterozygous null Viable Barcode deletion set, fitness test (haploinsufficient phenotype assay) PMID:17604452 orf19.2045 CAL0004414 Heterozygous null Viable Barcode deletion set, fitness test (haploinsufficient phenotype assay) PMID:17604452 orf19.2046 POT1-2 CAL0004416 Heterozygous null Viable Barcode deletion set, fitness test (haploinsufficient phenotype assay) PMID:17604452 orf19.2047 CAL0004417 Heterozygous null Viable Barcode deletion set, fitness test (haploinsufficient phenotype assay) PMID:17604452 orf19.2050 CAL0004431 Heterozygous null Viable Barcode deletion set, fitness test (haploinsufficient phenotype assay) PMID:17604452 orf19.2054 FGR15 CAL0004440 Unknown/unspecified Filamentous growth abnormal Increased or decreased filamentous growth, depending on the allele (solid Spider medium); heterozygous transposon mutant allele PMID:12773383 orf19.2054 FGR15 CAL0004440 Homozygous null Viable Insertion mutation, supplementary data PMID:15964282 orf19.2054 FGR15 CAL0004440 Homozygous null Wild-type biofilm formation Insertion mutation, supplementary data PMID:15964282 orf19.2054 FGR15 CAL0004440 Homozygous null Drug susceptibility altered Slight increase in caspofungin sensitivity PMID:16552442 orf19.2054 FGR15 CAL0004440 Homozygous null Viable PMID:16552442 orf19.2055 NPL6 CAL0004441 Heterozygous null Viable Barcode deletion set, fitness test (haploinsufficient phenotype assay) PMID:17604452 orf19.2057 CAL0004443 Heterozygous null Viable Barcode deletion set, fitness test (haploinsufficient phenotype assay) PMID:17604452 orf19.2059 CAL0004444 Heterozygous null Viable Barcode deletion set, fitness test (haploinsufficient phenotype assay) PMID:17604452 orf19.2060 SOD5 CAL0004456 Heterozygous null Viable PMID:14617819|PMID:15813733 orf19.2060 SOD5 CAL0004456 Homozygous null Virulence defect Decreased kidney colonization (mouse systemic infection) PMID:14617819 orf19.2060 SOD5 CAL0004456 Homozygous null Oxidative stress susceptibility altered Increased H2O2 sensitivity on minimal media PMID:14617819 orf19.2060 SOD5 CAL0004456 Heterozygous null Oxidative stress susceptibility altered Intermediate H2O2 sensitivity on minimal media PMID:14617819 orf19.2060 SOD5 CAL0004456 Homozygous null Virulence defect Decreased virulence (mouse systemic infection) PMID:14617819 orf19.2060 SOD5 CAL0004456 Heterozygous null Virulence defect Intermediate virulence (mouse systemic infection) PMID:14617819 orf19.2060 SOD5 CAL0004456 Homozygous null Viable PMID:14617819|PMID:15813733 orf19.2060 SOD5 CAL0004456 Heterozygous null Virulence defect Decreased kidney colonization (mouse systemic infection) PMID:14617819 orf19.2060 SOD5 CAL0004456 Homozygous null Wild-type virulence Wild-type sensitivity to macrophage killing PMID:14617819 orf19.2060 SOD5 CAL0004456 Homozygous null Virulence defect Decreased virulence (mouse intravenous infection) PMID:15813733 orf19.2060 SOD5 CAL0004456 Homozygous null Abnormal response to host Increased sensitivity to human whole blood or granulocytes PMID:15813733 orf19.2061 CAL0004459 Homozygous null Viable PMID:14663094 orf19.2064 CAL0004467 Homozygous null (inferred) Inviable Insertion mutation, supplementary data PMID:15964282 orf19.2065 CAL0004469 Heterozygous null Viable Barcode deletion set, fitness test (haploinsufficient phenotype assay) PMID:17604452 orf19.2067 CAL0004471 Heterozygous null Viable Barcode deletion set, fitness test (haploinsufficient phenotype assay) PMID:17604452 orf19.2069 SMF3 CAL0004473 Heterozygous null Viable Barcode deletion set, fitness test (haploinsufficient phenotype assay) PMID:17604452 orf19.207 PGA55 CAL0003874 Heterozygous null Viable Barcode deletion set, fitness test (haploinsufficient phenotype assay) PMID:17604452 orf19.2070 CAL0004485 Heterozygous null Viable Barcode deletion set, fitness test (haploinsufficient phenotype assay) PMID:17604452 orf19.2072 CAL0004491 Heterozygous null Viable Barcode deletion set, fitness test (haploinsufficient phenotype assay) PMID:17604452 orf19.2073 CAL0004494 Heterozygous null Viable Barcode deletion set, fitness test (haploinsufficient phenotype assay) PMID:17604452 orf19.2075 DFG5 CAL0004498 Homozygous null Viable PMID:12912894 orf19.2075 DFG5 CAL0004498 Homozygous null Filamentous growth abnormal Abolished filamentous growth (alkaline (pH 8) liquid or solid medium) PMID:12912894 orf19.2075 DFG5 CAL0004498 Heterozygous null Viable Barcode deletion set, fitness test (haploinsufficient phenotype assay) PMID:17604452 orf19.2077 CAL0004500 Homozygous null (inferred) Inviable Insertion mutation, supplementary data PMID:15964282 orf19.2077 CAL0004500 Heterozygous null Viable Barcode deletion set, fitness test (haploinsufficient phenotype assay) PMID:17604452 orf19.2078 CAL0004501 Heterozygous null Viable Barcode deletion set, fitness test (haploinsuf