GWEIGHT	G648S Exp1	G648S Exp2	G648D Exp1	G648D Exp2	Y642F Exp1	Y642F Exp2	A643V Exp1	A643V Exp2
EWEIGHT			1	1	1	1	1	1	1	1
0	|| orf19.4682 || HGT17 ||  || Putative MFS family glucose transporter; 20 members in C. albicans; 12 probable membrane-spanning segments; induced at low (0.2%, compared to 2%) glucose in rich media; Spider biofilm induced ||	1	-0.58	-0.34	0.58	0.24	-0.36	-0.11	1.22	1.10
1	|| orf19.5862 || AFP99 ||  || Protein related to arginases; downregulated upon adherence to polystyrene; regulated by Gcn2p and Gcn4p ||	1	-0.91	1.51	1.24	0.77	-0.22	-0.20	0.79	-0.57
2	|| orf19.11618 ||  ||  ||  ||	1	0.55	0.70	0.67	-0.47	-0.17	-0.03	0.83	-0.34
3	|| orf19.1341 || PRR2 ||  || Putative serine/threonine protein kinase; mutation confers resistance to 5-fluorocytosine (5-FC) ||	1	0.80	0.47	1.72	0.62	-0.67	0.92	1.45	-0.24
4	|| orf19.3437 ||  ||  || Has domain(s) with predicted serine-type endopeptidase activity and role in proteolysis ||	1	1.32	1.21	1.31	0.95	-2.71	0.01	1.18	0.37
5	|| orf19.980 ||  ||  || Ortholog(s) have inositol heptakisphosphate kinase activity, inositol hexakisphosphate 1-kinase activity, inositol hexakisphosphate 3-kinase activity, inositol hexakisphosphate 4-kinase activity, inositol hexakisphosphate 6-kinase activity ||	1	0.75	0.57	0.93	0.43	-0.39	0.36	-0.41	0.19
6	|| orf19.1341 || PRR2 ||  || Putative serine/threonine protein kinase; mutation confers resistance to 5-fluorocytosine (5-FC) ||	1	0.58	1.33	1.53	0.09	-0.11	-0.09	0.16	0.70
7	|| orf19.3538 || FRE9 ||  || Ferric reductase; alkaline induced; ciclopirox olamine; Hap43-induced ||	1	1.10	0.62	0.29	0.46	-0.04	0.38	0.32	0.77
8	|| orf19.1406 ||  ||  || Ortholog(s) have DNA-directed DNA polymerase activity, role in error-free translesion synthesis, error-prone translesion synthesis and mitochondrion, nuclear chromatin, zeta DNA polymerase complex localization ||	1	0.03	0.06	1.07	0.59	0.18	-0.44	0.87	-0.20
9	|| orf19.1462 || SMP2 ||  || Putative Mg2+-dependent phosphatidate phosphatase; transcript regulated by Nrg1 ||	1	0.08	-0.03	0.78	0.54	0.45	-0.23	0.65	0.08
10	|| orf19.1941 || NUF2 ||  || Kinetochore component; amount of Nuf2p and Mtw1p protein detected at each centromere is consistent with a single kinetochore microtubule attachment site ||	1	0.15	0.08	0.71	0.56	0.44	-0.36	0.65	0.08
11	|| orf19.5320 || NCE4 ||  || Putative RecQ-mediated genome instability protein; Hap43-repressed gene; periodic mRNA expression, peak at cell-cycle G2/M phase; flow model biofilm induced ||	1	0.25	-0.28	0.81	0.65	0.69	-0.31	1.02	0.12
12	|| orf19.2888 ||  ||  || Ortholog(s) have role in early endosome to Golgi transport, protein complex assembly and Golgi apparatus, TRAPP complex, clathrin-coated vesicle localization ||	1	0.44	-0.42	0.85	0.64	1.16	-0.30	1.35	-0.02
13	|| orf19.5097 || CAT8 ||  || Zn(II)2Cys6 transcription factor; similar to S. cerevisiae Cat8 but mutant phenotype suggests different target genes; mutant displays increased filamentous/invasive growth; flucytosine repressed; rat catheter biofilm induced ||	1	0.65	-0.60	0.98	1.06	0.04	0.11	1.27	0.11
14	|| orf19.7585 || INO1 ||  || Inositol-1-phosphate synthase; antigenic in human; repressed by farnesol in biofilm or by caspofungin; upstream inositol/choline regulatory element; glycosylation predicted; rat catheter, flow model induced; Spider biofilm repressed ||	1	0.28	-0.69	0.53	0.61	0.74	0.22	1.31	0.72
15	|| orf19.5547 ||  ||  || Protein of unknown function; Hap43-repressed gene ||	1	1.62	-0.22	0.74	0.66	2.52	0.33	1.77	-0.18
16	|| orf19.6589 || SSF1 ||  || Protein involved in ribosome biogenesis; ortholog of S. cerevisiae Ssf1; Hap43-induced; rat catheter and Spider biofilm induced ||	1	1.12	-0.20	0.49	0.35	1.09	0.61	0.75	0.22
17	|| orf19.6356 ||  ||  || Ortholog(s) have role in mRNA splicing, via spliceosome and U4/U6 x U5 tri-snRNP complex localization ||	1	1.16	-0.24	0.44	0.08	0.91	0.64	0.31	0.02
18	|| orf19.2650.1 ||  ||  || Mitochondrial ribosomal protein of the small subunit; Spider biofilm repressed ||	1	0.53	0.24	0.75	0.64	0.82	0.63	0.35	0.10
19	|| orf19.6805 ||  ||  || Protein of unknown function; Spider biofilm induced ||	1	0.86	0.37	1.47	0.67	1.08	0.60	0.54	0.03
20	|| orf19.6920 ||  ||  || Protein of unknown function; induced during chlamydospore formation in both C. albicans and C. dubliniensis; Hap43-induced gene; Spider biofilm induced; F-12/CO2 early biofilm induced ||	1	1.01	0.85	1.44	1.07	0.67	0.43	0.59	-0.18
21	|| orf19.6920 ||  ||  || Protein of unknown function; induced during chlamydospore formation in both C. albicans and C. dubliniensis; Hap43-induced gene; Spider biofilm induced; F-12/CO2 early biofilm induced ||	1	1.01	0.85	1.44	1.07	0.67	0.43	0.59	-0.18
22	|| orf19.6982 ||  ||  || Ortholog(s) have ribosome binding activity and mitochondrion localization ||	1	0.80	0.63	0.45	0.33	0.75	0.13	0.50	0.15
23	|| orf19.6351 ||  ||  || Ortholog of <i>C. dubliniensis CD36</i> : Cd36_11880, <i>Candida tenuis NRRL Y-1498</i> : cten_CGOB_00231, <i>Debaryomyces hansenii CBS767</i> : DEHA2D04928g and <i>Pichia stipitis Pignal</i> : PICST_29234 ||	1	0.73	0.77	0.34	0.47	1.26	-0.13	0.55	-0.01
24	|| orf19.2006 ||  ||  || Ortholog(s) have fungal-type vacuole membrane localization ||	1	1.32	0.72	1.50	1.08	1.77	-0.22	0.82	-0.10
25	|| orf19.2006 ||  ||  || Ortholog(s) have fungal-type vacuole membrane localization ||	1	1.32	0.72	1.50	1.08	1.77	-0.22	0.82	-0.10
26	|| orf19.6460 || PEX1 ||  || Ortholog(s) have ATPase activity, protein heterodimerization activity, role in fatty acid metabolic process, protein import into peroxisome matrix, receptor recycling and cytosol, peroxisomal membrane localization ||	1	0.58	-0.03	0.74	0.63	0.66	-0.37	0.74	0.09
27	|| orf19.1828 || BUD16 ||  || Putative pyridoxal kinase; a key enzyme in pyridoxal 5'-phosphate synthesis, the active form of vitamin B6; involved in bud-site selection and genome integrity in S. cerevisiae; induced by alpha pheromone in SpiderM medium ||	1	1.29	-0.22	1.45	0.56	1.06	-0.29	1.04	-0.12
28	|| orf19.2755 ||  ||  || Ortholog(s) have role in proteasomal ubiquitin-independent protein catabolic process, proteasome-mediated ubiquitin-dependent protein catabolic process and cytosol, nucleus, proteasome core complex, beta-subunit complex localization ||	1	0.70	-0.14	1.00	0.65	1.00	-0.11	0.64	-0.58
29	|| orf19.4583 ||  ||  || Protein with a mitochondrial carrier protein domain; possibly an essential gene, disruptants not obtained by UAU1 method; Spider biofilm repressed ||	1	1.18	0.12	0.90	0.69	0.89	0.23	1.02	-0.40
30	|| orf19.911 ||  ||  || Predicted ORF from Assembly 19; merged with orf19.5776 in Assembly 20 ||	1	1.22	0.67	0.86	0.32	0.46	0.30	0.92	-0.14
31	|| orf19.4711 ||  ||  || Ortholog of <i>C. dubliniensis CD36</i> : Cd36_40890, <i>C. parapsilosis CDC317</i> : CPAR2_401100, <i>Candida tenuis NRRL Y-1498</i> : CANTEDRAFT_119698 and <i>Debaryomyces hansenii CBS767</i> : DEHA2G22154g ||	1	1.92	0.77	2.30	0.43	0.78	0.02	1.90	-0.19
32	|| orf19.3121 || GST1 ||  || Putative glutathione S-transferase; upregulated in the presence of human neutrophils; expression is regulated upon white-opaque switching; increased transcription is observed upon benomyl treatment ||	1	2.96	1.03	5.25	0.31	4.03	-0.13	3.76	-0.20
33	|| orf19.4608 || PDC12 ||  || Putative pyruvate decarboxylase; fungal-specific (no human or murine homolog) ||	1	1.22	0.39	1.92	0.56	1.58	-0.01	1.71	-0.07
34	|| orf19.2508 || PRM9 ||  || Protein described a similar to S. cerevisiae Prm9; not the ortholog though; mutant is viable ||	1	3.82	1.56	3.92	0.66	3.73	1.39	3.78	0.26
35	|| orf19.2238 || LTE1 ||  || Protein similar to GDP/GTP exchange factors; repressed by alpha pheromone in SpiderM medium; flow model biofilm repressed ||	1	4.19	0.96	3.30	-1.06	4.25	0.40	3.33	-0.26
36	|| orf19.3156 ||  ||  || Protein of unknown function; induced by Mnl1 under weak acid stress ||	1	1.04	0.55	0.95	-0.03	0.74	0.02	0.56	-0.06
37	|| orf19.6979 ||  ||  || Ortholog(s) have role in cellular manganese ion homeostasis, mitochondrion organization and fungal-type vacuole membrane localization ||	1	0.81	0.55	1.11	-0.07	0.66	0.16	0.42	0.07
38	|| orf19.3519 || SUA72 ||  || Predicted transcription factor; induced during planktonic growth, whereas related SUA71 is downregulated ||	1	0.54	0.75	1.17	-0.28	0.34	-0.06	0.74	0.27
39	|| orf19.2839 || CIRT4B ||  || Cirt family transposase; transcript repressed in an azole-resistant strain that overexpresses CDR1 and CDR2; Hap43-repressed; flow model biofilm induced ||	1	0.92	0.75	1.55	0.32	0.47	-0.90	1.77	0.59
40	|| orf19.302 ||  ||  || Ortholog(s) have Rab guanyl-nucleotide exchange factor activity, role in ER to Golgi vesicle-mediated transport and TRAPP complex, cytosol, nucleus localization ||	1	0.73	0.55	0.36	0.17	-0.00	-0.44	0.48	0.22
41	|| orf19.742 || ALD6 ||  || Putative aldehyde dehydrogenase; stationary phase enriched protein; expression regulated upon white-opaque switch; rat catheter biofilm induced; rat catheter and Spider biofilm induced ||	1	1.40	1.66	0.53	0.29	0.76	-0.58	0.82	0.63
42	|| orf19.7303 ||  ||  || Ortholog of <i>C. dubliniensis CD36</i> : Cd36_34495, <i>Candida tropicalis MYA-3404</i> : CTRG_05947 and <i>Candida albicans WO-1</i> : CAWG_02181 ||	1	1.81	1.48	0.84	-0.50	0.47	0.25	1.93	0.42
43	|| orf19.1768 ||  ||  || Ortholog of <i>C. parapsilosis CDC317</i> : CPAR2_407480, <i>C. dubliniensis CD36</i> : Cd36_24170, <i>Candida orthopsilosis Co 90-125</i> : CORT_0C06830 and <i>Spathaspora passalidarum NRRL Y-27907</i> : SPAPADRAFT_65786 ||	1	0.70	0.79	0.36	0.00	0.66	0.10	0.68	-0.20
44	|| orf19.262 || SMC3 ||  || Protein similar to S. cerevisiae Smc3p, which is an ATPase involved in sister chromatid cohesion; likely to be essential for growth, based on an insertional mutagenesis strategy ||	1	0.56	0.75	0.42	-0.09	0.84	-0.39	0.45	-0.50
45	|| orf19.4735 ||  ||  || Ornithine cyclodeaminase family protein; Sef1, Sfu1, and Hap43-regulated; ortholog of S. cerevisiae YGL159W and S. pombe SPAP11E10.01; rat catheter biofilm induced ||	1	0.56	0.72	0.54	0.12	0.30	-0.37	0.50	-0.28
46	|| orf19.6311 ||  ||  || Protein of unknown function; Hap43-induced; rat catheter and Spider biofilm induced ||	1	0.05	2.07	1.95	2.16	1.06	0.74	0.51	0.20
47	|| orf19.3998 ||  ||  || Ortholog(s) have Atg8 ligase activity, protein binding, bridging activity and role in C-terminal protein lipidation, CVT pathway, macroautophagy, mitochondrion degradation, piecemeal microautophagy of nucleus ||	1	0.58	0.69	1.89	0.71	1.03	-0.85	0.94	0.18
48	|| orf19.6790 ||  ||  || Ortholog(s) have mRNA binding activity, role in 3'-UTR-mediated mRNA destabilization, mitochondrion organization and cytoplasmic mRNA processing body, cytoplasmic stress granule, cytosol, perinuclear region of cytoplasm localization ||	1	0.62	0.55	1.47	0.60	0.69	-0.58	0.36	-0.21
49	|| orf19.6790 ||  ||  || Ortholog(s) have mRNA binding activity, role in 3'-UTR-mediated mRNA destabilization, mitochondrion organization and cytoplasmic mRNA processing body, cytoplasmic stress granule, cytosol, perinuclear region of cytoplasm localization ||	1	0.62	0.55	1.47	0.60	0.69	-0.58	0.36	-0.21
50	|| orf19.6308 ||  ||  || Ortholog of <i>Candida albicans WO-1</i> : CAWG_01818 ||	1	0.60	0.63	0.86	0.58	0.53	-0.29	0.58	-0.07
51	|| orf19.6308 ||  ||  || Ortholog of <i>Candida albicans WO-1</i> : CAWG_01818 ||	1	0.60	0.63	0.86	0.58	0.53	-0.29	0.58	-0.07
52	|| orf19.3112 || ZRT1 ||  || Putative zinc transporter; acts with Pra1 in sequestration of zinc from host tissues during infection; hyphal, macrophage-induced; alkaline induced upon adherence to polystyrene; induced in oralpharyngeal candidasis; Spider biofilm induced ||	1	0.59	0.67	0.65	0.49	0.08	-0.35	0.22	0.01
53	|| orf19.4791 ||  ||  || Protein of unknown function; Spider biofilm induced ||	1	0.32	0.86	1.23	0.67	-0.02	-0.56	0.59	0.15
54	|| orf19.6601 ||  ||  || Protein of unknown function; rat catheter and flow model biofilm induced ||	1	-0.16	0.71	1.47	0.70	0.12	-0.43	0.53	0.21
55	|| orf19.2768 || AMS1 ||  || Putative alpha-mannosidase; transcript regulated by Nrg1; induced during cell wall regeneration; flow model biofilm induced; Spider biofilm induced ||	1	0.12	1.46	2.05	0.98	0.34	-0.27	0.35	0.33
56	|| orf19.1763 || IFR1 ||  || Predicted oxidoreductase/dehydrogenase; induced by nitric oxide; rat catheter and Spider biofilm induced ||	1	0.17	1.73	1.98	0.89	0.65	0.11	1.04	0.51
57	|| orf19.5935 ||  ||  || Ortholog of <i>C. dubliniensis CD36</i> : Cd36_84710, <i>C. parapsilosis CDC317</i> : CPAR2_807470, <i>Candida tenuis NRRL Y-1498</i> : CANTEDRAFT_136475 and <i>Debaryomyces hansenii CBS767</i> : DEHA2B08844g ||	1	0.39	1.30	0.82	0.74	0.32	0.14	0.50	0.26
58	|| orf19.689 || PLB1 ||  || Phospholipase B; host cell penetration and virulence in mouse systemic infection; Hog1-induced; signal sequence, N-glycosylation, and Tyr phosphorylation site; induced in fluconazole-resistant strains; rat catheter biofilm repressed ||	1	0.70	0.97	0.92	0.31	0.41	0.09	0.51	0.08
59	|| orf19.3813 ||  ||  || Ortholog of <i>C. dubliniensis CD36</i> : Cd36_44340, <i>C. parapsilosis CDC317</i> : CPAR2_302240, <i>Candida tenuis NRRL Y-1498</i> : CANTEDRAFT_105331 and <i>Debaryomyces hansenii CBS767</i> : DEHA2E03454g ||	1	0.62	0.82	1.41	0.44	0.46	-0.07	1.28	0.07
60	|| orf19.5295 ||  ||  || Protein with a predicted endonuclease/exonuclease/phosphatase family domain and a carbon catabolite repressor protein 4 domain; induced by alpha pheromone in SpiderM medium ||	1	0.68	1.05	1.30	0.70	-0.11	-0.14	0.95	0.43
61	|| orf19.5295 ||  ||  || Protein with a predicted endonuclease/exonuclease/phosphatase family domain and a carbon catabolite repressor protein 4 domain; induced by alpha pheromone in SpiderM medium ||	1	0.68	1.05	1.30	0.70	-0.11	-0.14	0.95	0.43
62	|| orf19.4177 || HIS5 ||  || Putative histidinol-phosphate aminotransferase; Gcn4p-regulated; protein present in exponential and stationary growth phase yeast cultures ||	1	0.34	0.56	0.59	0.58	0.07	-0.38	0.73	0.30
63	|| orf19.4691 || MRV1 ||  || Ortholog of <i>Candida albicans WO-1</i> : CAWG_03682 ||	1	0.20	0.44	1.32	1.01	-0.19	-0.40	0.03	0.42
64	|| orf19.6556 ||  ||  || Protein of unknown function; rat catheter, flow model and Spider biofilm induced ||	1	0.08	0.17	0.76	0.58	0.16	-0.23	0.01	-0.14
65	|| orf19.7365 ||  ||  || Ortholog(s) have ubiquitin-protein ligase activity and role in negative regulation of apoptotic process, negative regulation of gluconeogenesis, proteasome-mediated ubiquitin-dependent protein catabolic process ||	1	0.21	-0.07	0.75	0.55	0.15	-0.11	0.16	-0.08
66	|| orf19.1070 ||  ||  || Ortholog(s) have cytoplasm localization ||	1	-0.04	0.31	1.98	1.16	0.30	-0.18	0.73	0.28
67	|| orf19.1434 ||  ||  || Ortholog(s) have protein kinase activator activity ||	1	0.07	0.01	0.94	0.75	0.04	0.06	0.43	0.05
68	|| orf19.3214 ||  ||  || Alpha/beta-HydrolasE superfamily protein; membrane-localized ||	1	0.30	0.55	1.29	1.20	0.34	0.15	0.77	0.07
69	|| orf19.225 ||  ||  || Predicted 2-hydroxyacid dehydrogenase; Hap43-repressed gene ||	1	0.09	0.44	1.03	0.71	0.38	-0.02	0.32	0.31
70	|| orf19.6773 || ECM29 ||  || Putative scaffold protein; assists in association of the proteasome core particle with the regulatory particle; ortholog of S. cerevisiae Ecm29; transposon mutation affects filamentous growth; flow model biofilm repressed ||	1	0.10	0.29	0.59	0.60	0.35	-0.05	0.29	0.26
71	|| orf19.5239 ||  ||  || Predicted alanine-tRNA ligase; oxidative stress-induced via Cap1 ||	1	-0.06	0.85	1.24	1.08	0.86	0.05	0.55	0.61
72	|| orf19.7507 ||  ||  || Ortholog of <i>C. dubliniensis CD36</i> : Cd36_25310, <i>Pichia stipitis Pignal</i> : PICST_30877, <i>Candida tropicalis MYA-3404</i> : CTRG_01053 and <i>Candida lusitaniae ATCC 42720</i> : CLUG_02644 ||	1	-0.11	0.43	0.70	0.78	0.41	-0.25	0.13	0.32
73	|| orf19.6462 ||  ||  || Ortholog(s) have role in protein folding in endoplasmic reticulum and ER membrane protein complex, cytosol localization ||	1	-0.10	0.06	0.63	1.08	0.31	0.08	0.26	0.45
74	|| orf19.3984 ||  ||  || Protein of unknown function; induced in core caspofungin response; induced in ssr1 mutant; induced by nitric oxide independent of Yhb1; Spider biofilm induced ||	1	0.02	0.04	0.69	0.82	0.42	-0.25	0.39	0.28
75	|| orf19.5008.1 || DAD1 ||  || Subunit of the Dam1 (DASH) complex, which acts in chromosome segregation by coupling kinetochores to spindle microtubules ||	1	-0.12	0.15	0.57	0.91	0.19	-0.30	0.36	0.05
76	|| orf19.4807 ||  ||  || Ortholog(s) have inorganic diphosphatase activity, role in aerobic respiration and mitochondrion localization ||	1	0.23	0.19	0.59	0.62	0.01	-0.20	0.36	0.23
77	|| orf19.5014 ||  ||  || Ortholog(s) have mitochondrion localization ||	1	0.16	0.10	0.57	0.69	0.06	-0.17	0.27	0.26
78	|| orf19.1496 ||  ||  || Putative transcription factor with zinc finger DNA-binding motif; Hap43p-repressed gene ||	1	0.35	0.16	0.67	0.70	0.26	-0.30	0.37	0.51
79	|| orf19.5952 ||  ||  || Protein of unknown function; induced by nitric oxide independent of Yhb1; Sef1, Sfu1, and Hap43-induced; rat catheter and Spider biofilm induced ||	1	0.19	0.05	0.65	0.63	0.15	-0.17	0.12	0.67
80	|| orf19.5818 || SUR2 ||  || Putative ceramide hydroxylase; predicted enzyme of sphingolipid biosynthesis; regulated by Tsa1, Tsa1B under H2O2 stress conditions; Spider and flow model biofilm induced ||	1	0.03	0.18	0.47	0.14	0.22	0.10	0.57	0.65
81	|| orf19.6393 ||  ||  || Putative Arf3p GTPase activating protein; Hap43p-repressed gene; possibly an essential gene, disruptants not obtained by UAU1 method ||	1	0.05	0.31	0.51	0.21	0.33	-0.05	0.96	0.56
82	|| orf19.4595 ||  ||  || Ortholog of <i>C. dubliniensis CD36</i> : Cd36_41860, <i>C. parapsilosis CDC317</i> : CPAR2_400440, <i>Candida tenuis NRRL Y-1498</i> : CANTEDRAFT_103033 and <i>Debaryomyces hansenii CBS767</i> : DEHA2B03234g ||	1	-0.04	0.34	0.34	0.37	0.13	-0.10	0.60	0.56
83	|| orf19.676 ||  ||  || Microtubule-binding protein of the cortical microtubule; delays exit from mitosis when the spindle is abnormally oriented; Spider biofilm repressed ||	1	0.16	0.27	0.48	0.42	0.11	-0.30	0.66	0.54
84	|| orf19.4504 ||  ||  || Has domain(s) with predicted oxidoreductase activity, transferase activity, transferring acyl groups other than amino-acyl groups, zinc ion binding activity and role in oxidation-reduction process ||	1	0.53	0.34	0.62	0.51	0.26	-0.27	1.09	0.75
85	|| orf19.6973 ||  ||  || ATP-dependent LON protease family member; Hap43-repressed gene; regulated by Gcn2 and Gcn4; Spider biofilm induced ||	1	0.15	0.39	0.76	0.33	0.29	-0.34	0.57	0.56
86	|| orf19.6031 || VPS27 ||  || Putative ESCRT-0 complex protein with a role in multivesicular body (MVB) trafficking ||	1	0.10	0.29	1.28	0.46	0.65	-0.07	0.78	0.67
87	|| orf19.7225 ||  ||  || Ortholog of <i>C. dubliniensis CD36</i> : Cd36_13150, <i>C. parapsilosis CDC317</i> : CPAR2_700610, <i>Candida tenuis NRRL Y-1498</i> : CANTEDRAFT_135418 and <i>Debaryomyces hansenii CBS767</i> : DEHA2B01298g ||	1	0.30	0.18	1.08	0.55	0.03	-0.18	0.82	0.41
88	|| orf19.2303 || FGR16 ||  || Protein lacking an ortholog in S. cerevisiae; transposon mutation affects filamentous growth; fluconazole-downregulated ||	1	1.26	0.17	0.88	0.57	0.74	0.07	1.06	0.32
89	|| orf19.5037 || HRQ2 ||  || Protein of unknown function; mutants are viable; rat catheter and Spider biofilm induced ||	1	1.63	0.61	1.22	1.01	1.01	0.28	1.41	0.83
90	|| orf19.1988 || CDC45 ||  || Putative DNA replication initiation factor; transcriptionally regulated by interaction with macrophage ||	1	0.66	0.28	0.75	0.39	0.71	-0.04	0.58	0.61
91	|| orf19.6986 ||  ||  || Has domain(s) with predicted Rab GTPase activator activity, role in regulation of Rab GTPase activity and intracellular localization ||	1	1.28	0.86	1.33	1.16	1.50	0.26	1.36	1.12
92	|| orf19.1392 ||  ||  || Ortholog(s) have chaperone binding, protein disulfide isomerase activity, unfolded protein binding activity and role in ER-associated ubiquitin-dependent protein catabolic process, protein retention in ER lumen ||	1	0.63	0.30	0.60	0.79	0.94	-0.02	1.02	0.43
93	|| orf19.4766 || ARG81 ||  || Zn(II)2Cys6 transcription factor; required for utilization of ornithine as a nitrogen source and for wild-type resistance to caffeine; required for yeast cell adherence to silicone substrate ||	1	0.72	0.59	0.94	0.68	0.98	-0.07	0.73	0.29
94	|| orf19.4983 ||  ||  || Ortholog of <i>C. dubliniensis CD36</i> : Cd36_12520, <i>C. parapsilosis CDC317</i> : CPAR2_201720, <i>Candida tenuis NRRL Y-1498</i> : CANTEDRAFT_108003 and <i>Debaryomyces hansenii CBS767</i> : DEHA2D05214g ||	1	0.64	0.29	0.72	0.71	1.00	-0.02	0.75	0.22
95	|| orf19.2469 || RAD10 ||  || Ortholog of S. cerevisiae Rad10, an endonuclease involved in nucleotide excision repair; mutant is extremely sensitive to UV irradiation; transcript repressed in alkaline conditions ||	1	0.78	0.29	0.57	0.61	0.79	0.10	0.71	0.13
96	|| orf19.5772 ||  ||  || Ortholog(s) have role in histone exchange and Swr1 complex, cytosol localization ||	1	0.83	0.57	0.75	0.68	0.90	0.27	0.94	0.20
97	|| orf19.5772 ||  ||  || Ortholog(s) have role in histone exchange and Swr1 complex, cytosol localization ||	1	0.83	0.57	0.75	0.68	0.90	0.27	0.94	0.20
98	|| orf19.4168 ||  ||  || Ortholog(s) have ribonuclease MRP activity, ribonuclease P activity, role in intronic box C/D snoRNA processing, mRNA cleavage and nucleolar ribonuclease P complex, ribonuclease MRP complex localization ||	1	0.70	0.79	0.70	0.72	1.19	0.43	0.93	0.19
99	|| orf19.4168 ||  ||  || Ortholog(s) have ribonuclease MRP activity, ribonuclease P activity, role in intronic box C/D snoRNA processing, mRNA cleavage and nucleolar ribonuclease P complex, ribonuclease MRP complex localization ||	1	0.70	0.79	0.70	0.72	1.19	0.43	0.93	0.19
100	|| orf19.345 ||  ||  || Succinate semialdehyde dehydrogenase; for utilization of gamma-aminobutyrate (GABA) as a nitrogen source; part of 4-aminobutyrate and glutamate degradation pathways; rat catheter biofilm induced ||	1	1.04	0.53	0.68	0.86	1.22	0.59	0.90	0.41
101	|| orf19.7061 ||  ||  || Ortholog(s) have ATPase activity and cytosol, nucleus localization ||	1	0.99	0.02	1.02	0.54	1.07	0.46	1.21	0.35
102	|| orf19.6268 ||  ||  || Putative cohesin complex subunit; expression downregulated in an ssr1 null mutant ||	1	0.76	0.08	0.88	0.57	0.97	0.16	0.84	0.31
103	|| orf19.3939 ||  ||  || Ortholog(s) have role in protein folding in endoplasmic reticulum and ER membrane protein complex, cell division site, cytosol, mitotic spindle pole body, nucleus localization ||	1	1.16	0.20	1.10	0.57	1.30	0.15	1.24	0.24
104	|| orf19.1776 ||  ||  || Putative pantetheine-phosphate adenylyltransferase (PPAT); which catalyzes 4th step in coenzyme A biosynthesis from pantothenate; rat catheter biofilm repressed ||	1	1.36	0.18	1.61	1.08	1.99	0.08	2.12	0.34
105	|| orf19.6967 || USO6 ||  || Putative vesicular transport protein; transcript induced by filamentous growth; rat catheter biofilm repressed ||	1	0.81	0.55	1.43	0.69	0.89	-0.13	0.97	-0.02
106	|| orf19.6967 || USO6 ||  || Putative vesicular transport protein; transcript induced by filamentous growth; rat catheter biofilm repressed ||	1	0.81	0.55	1.43	0.69	0.89	-0.13	0.97	-0.02
107	|| orf19.4592 || HSX11 ||  || UDP-glucose:ceramide glucosyltransferase (glucosylceramide synthase [GCS], EC 2.4.1.80); involved in glucosylceramide biosynthesis, which is important for virulence ||	1	1.03	0.46	1.25	0.70	0.94	0.09	1.08	0.21
108	|| orf19.4357 ||  ||  || Putative protein similar to S. cerevisiae Mgr3p, a subunit of the i-AAA protease supercomplex that degrades misfolded mitochondrial proteins ||	1	0.70	0.22	1.09	0.57	0.60	0.01	0.74	0.29
109	|| orf19.5662 || PEP7 ||  || Vesicle transport protein; acts in endosomal transport; roles in metal ion resistance, virulence, adhesion, hyphal growth, chlamydospore formation; similar to S. cerevisiae Pep7p ||	1	0.60	0.19	0.94	0.74	0.77	-0.29	0.70	0.46
110	|| orf19.6003 ||  ||  || Protein of unknown function; role in intracellular signal transduction; Spider biofilm induced ||	1	0.70	0.40	1.13	0.80	0.67	-0.30	0.67	0.62
111	|| orf19.1481 || HAP42 ||  || Predicted transcription factor; possibly an essential gene, disruptants not obtained by UAU1 method ||	1	0.66	0.62	1.85	1.22	1.13	-0.06	1.09	0.63
112	|| orf19.5881 ||  ||  || Predicted ORF from Assembly 19; merged with orf19.5880 in Assembly 20 ||	1	0.50	0.23	1.05	0.64	0.47	-0.14	0.80	0.19
113	|| orf19.6200 ||  ||  || Pry family pathogenesis-related protein; oral infection upregulated gene; mutant has reduced capacity to damage oral epithelial cells ||	1	0.36	0.32	1.43	0.79	0.67	-0.37	1.10	0.49
114	|| orf19.5426 ||  ||  || Putative patatin-like phospholipase; macrophage-regulated gene; fungal-specific (no human or murine homolog) ||	1	0.76	0.89	1.37	0.96	0.54	-0.09	1.17	0.48
115	|| orf19.4346 ||  ||  || Ortholog(s) have protein anchor activity, role in COPII vesicle coating, protein localization to endoplasmic reticulum exit site and ER to Golgi transport vesicle membrane, endoplasmic reticulum exit site localization ||	1	0.68	0.72	1.27	0.82	0.64	-0.10	1.05	0.60
116	|| orf19.5337 || UBC15 ||  || Putative E2 ubiquitin-conjugating enzyme ||	1	0.45	0.45	0.85	0.58	0.41	0.05	0.74	0.44
117	|| orf19.1504 ||  ||  || Putative patatin-like phospholipase; fungal-specific (no human or murine homolog) ||	1	0.67	0.71	1.45	0.72	0.83	-0.05	1.57	0.70
118	|| orf19.5820 || UGA6 ||  || Putative GABA-specific permease; decreased transcription is observed upon benomyl treatment or in an azole-resistant strain that overexpresses MDR1 ||	1	0.74	0.94	1.87	0.60	0.74	-0.03	1.57	0.81
119	|| orf19.4584 || PHO114 ||  || Acid phosphatase; induced by Mnl1 under weak acid stress; Spider biofilm induced ||	1	0.75	0.68	1.13	0.49	0.82	-0.17	1.00	0.38
120	|| orf19.747 || NBP35 ||  || Similar to nucleotide-binding proteins; increased transcription is observed upon benomyl treatment; transcription is induced upon filamentous growth ||	1	0.85	0.58	1.06	0.43	0.63	-0.02	1.07	0.31
121	|| orf19.1698 ||  ||  || Ortholog(s) have phosphatidate phosphatase activity, role in actin cytoskeleton organization, cellular lipid metabolic process and actin cortical patch localization ||	1	0.73	0.39	1.20	0.60	0.68	0.03	1.12	0.80
122	|| orf19.6557 ||  ||  || Protein with a predicted fatty acid amide hydrolase I domain; induced by Mnl1 under weak acid stress ||	1	0.84	0.50	1.28	0.55	0.79	0.12	1.03	0.95
123	|| orf19.4015 || CAG1 ||  || heterotrimeric G protein alpha subunit; positive role in mating pheromone response; opaque-enriched transcript; transcript repressed by MTLa1-MTLalpha2; regulated by hemoglobin-responsive Hbr1 via MTL genes; rat catheter biofilm repressed ||	1	1.26	0.65	1.41	0.60	0.53	-0.17	1.07	0.59
124	|| orf19.1857 ||  ||  || Putative L-azetidine-2-carboxylic acid acetyltransferase; mutants are viable ||	1	0.78	0.31	1.15	0.67	0.94	0.02	1.07	0.58
125	|| orf19.3806 ||  ||  || Ortholog(s) have role in negative regulation of gluconeogenesis, proteasome-mediated ubiquitin-dependent protein catabolic process, traversing start control point of mitotic cell cycle and GID complex, cytoplasm, nucleus localization ||	1	0.50	0.23	1.01	0.55	1.02	-0.12	1.03	0.47
126	|| orf19.4726 ||  ||  || Ortholog(s) have calcium ion binding, enzyme activator activity ||	1	0.50	0.17	1.28	0.36	0.89	-0.25	1.24	0.65
127	|| orf19.1373 || INP51 ||  || Putative phosphatidylinositol-4,5-bisphosphate phosphatase; involved in maintenance of phosphoinositide levels; affects hyphal growth, virulence, cell integrity; interacts with Irs4p ||	1	0.89	0.04	1.32	0.58	0.73	-0.41	1.40	0.39
128	|| orf19.2710 ||  ||  || Ortholog(s) have enzyme activator activity, role in chromosome segregation and cytoplasm, nucleus localization ||	1	0.63	-0.03	1.51	0.58	1.06	-0.33	1.29	0.19
129	|| orf19.2346 ||  ||  || Putative protein of unknown function, transcription is positively regulated by Tbf1p ||	1	0.63	0.07	0.97	0.55	0.75	-0.26	0.80	0.29
130	|| orf19.2009 || PEX12 ||  || Ortholog(s) have ubiquitin-protein ligase activity, role in protein import into peroxisome matrix and integral to peroxisomal membrane localization ||	1	1.08	-0.03	1.35	0.64	1.50	-0.33	1.36	0.39
131	|| orf19.6569 ||  ||  || Predicted transmembrane transporter; induced during chlamydospore formation in both C. albicans and C. dubliniensis ||	1	0.93	0.09	1.05	0.72	0.60	0.16	1.40	0.42
132	|| orf19.4061 ||  ||  || Protein of unknown function; clade-associated gene expression ||	1	0.60	0.32	0.85	0.59	0.31	-0.01	1.07	0.33
133	|| orf19.834 ||  ||  || Ortholog(s) have carbohydrate binding, mannosyl-oligosaccharide 1,2-alpha-mannosidase activity, role in ER-associated ubiquitin-dependent protein catabolic process and endoplasmic reticulum lumen localization ||	1	0.60	0.20	0.95	0.61	0.54	0.32	0.76	-0.01
134	|| orf19.5367 || RDH54 ||  || Putative DNA-dependent ATPase with a predicted role in DNA recombination and repair; transcriptionally induced by interaction with macrophages ||	1	0.60	0.23	0.77	0.68	0.25	-0.13	0.69	0.11
135	|| orf19.3851 ||  ||  || Protein of unknown function; induced by alpha pheromone in SpiderM medium ||	1	0.57	0.65	1.05	0.11	-0.13	-0.08	0.69	0.65
136	|| orf19.3877 ||  ||  || Ortholog of <i>C. dubliniensis CD36</i> : Cd36_73360 and <i>Candida albicans WO-1</i> : CAWG_01936 ||	1	0.39	0.46	0.61	0.01	0.07	0.21	0.69	0.63
137	|| orf19.7561 || DEF1 ||  || RNA polymerase II regulator; role in filamentation, epithelial cell escape, dissemination in RHE model; induced by fluconazole, high cell density; Efg1/hyphal regulated; role in adhesion, hyphal growth on solid media; Spider biofilm induced ||	1	0.32	0.45	0.74	0.25	0.15	0.14	0.58	0.63
138	|| orf19.1288 || FOX2 ||  || 3-hydroxyacyl-CoA epimerase; fatty acid beta-oxidation; induced by phagocytosis; regulated by Mig1, by white-opaque switch, by DNA methylation; transcriptional activation by oleate requires Ctf1; rat catheter and Spider biofilm induced ||	1	0.38	0.34	0.54	0.39	0.04	0.08	0.69	0.57
139	|| orf19.136 ||  ||  || Predicted membrane transporter, member of the drug:proton antiporter (12 spanner) (DHA1) family, major facilitator superfamily (MFS); Hap43p-repressed gene ||	1	0.68	0.59	0.42	0.33	0.07	0.09	0.67	0.57
140	|| orf19.1297 ||  ||  || Ortholog(s) have phosphatidylinositol-3-phosphate binding activity and role in CVT pathway, early endosome to Golgi transport, macroautophagy, mitochondrion degradation ||	1	1.11	0.72	1.32	0.84	0.36	0.63	1.16	0.51
141	|| orf19.2296 ||  ||  || Predicted mucin-like protein; ketoconazole-induced; fluconazole-repressed; induced in cyr1 mutant; colony morphology-related gene regulation by Ssn6; flow model biofilm induced; Spider biofilm induced ||	1	1.11	1.27	1.85	0.28	0.75	0.91	1.44	0.91
142	|| orf19.2593 || BIO2 ||  || Putative biotin synthase; induced by high iron; repressed by ciclopirox olamine; upregulated in clinical isolates from HIV+ patients with oral candidiasis; Hap43-repressed; Spider biofilm induced ||	1	0.66	0.86	1.56	0.72	0.40	0.00	0.62	0.42
143	|| orf19.3215 ||  ||  || Putative plasma membrane protein; in S. cerevisiae it is localized to the cell bud and mating projection membrane; repressed by alpha pheromone in SpiderM medium ||	1	0.35	0.64	0.84	0.60	0.21	-0.04	0.54	0.21
144	|| orf19.1364 ||  ||  || Ortholog of S. pombe Stm1 G-protein coupled receptor; PQ-loop domains; constitutive expression independent of MTL or white-opaque status; Hap43-repressed ||	1	0.22	0.46	1.02	0.66	0.14	-0.15	0.62	0.27
145	|| orf19.5000 || CYB2 ||  || Putative cytochrome b2 precursor; induced in high iron; alkaline repressed; colony morphology-related gene regulation by Ssn6; Hap43-repressed; pider biofilm induced ||	1	0.11	0.41	0.88	0.56	0.32	-0.23	0.57	0.10
146	|| orf19.7288 ||  ||  || Protein with predicted oxidoreductase and dehydrogenase domains; Hap43-repressed; Spider biofilm induced ||	1	0.09	0.49	0.71	0.61	0.12	-0.19	0.44	0.52
147	|| orf19.3814 ||  ||  || Predicted ORF from Assembly 19; merged with orf19.3813 in Assembly 20 ||	1	0.10	0.50	0.82	0.72	0.14	-0.33	0.68	0.45
148	|| orf19.6349 || RVS162 ||  || Protein containing a BAR domain, which is found in proteins involved in membrane curvature; null mutant does not display the endocytic, hyphal growth, virulence, or cell wall defects exhibited by mutants in related genes RVS161 and RVS167 ||	1	0.17	0.76	0.85	0.61	0.23	-0.17	0.75	0.42
149	|| orf19.5125 ||  ||  || Protein of unknown function; induced by ketoconazole; Spider, F-12/CO2 and flow model biofilm induced ||	1	0.14	0.85	1.29	0.67	0.17	-0.32	0.88	0.62
150	|| orf19.3679 ||  ||  || Putative protein of unknown function; stationary phase enriched protein ||	1	0.04	0.73	1.15	0.62	0.03	-0.20	0.59	0.44
151	|| orf19.6690 ||  ||  || Protein of unknown function; Hap43-repressed gene ||	1	-0.14	0.54	1.00	0.52	-0.07	-0.16	0.57	0.61
152	|| orf19.4356 || HGT3 ||  || Putative glucose transporter of the major facilitator superfamily; the C. albicans glucose transporter family comprises 20 members; 12 probable membrane-spanning segments, extended C terminus; expressed in rich medium with 2% glucose ||	1	0.15	0.60	1.32	0.75	0.00	-0.03	0.95	0.78
153	|| orf19.3544 ||  ||  || Putative protein of unknown function; Hap43p-repressed gene ||	1	0.10	0.89	1.81	0.69	0.08	-0.06	1.28	0.90
154	|| orf19.897 || VPS20 ||  || ESCRT III complex protein; role in multivesicular body (MVB) trafficking; required for processing of Rim8; Bcr1-repressed in RPMI a/a biofilms ||	1	0.12	0.22	0.55	0.46	0.11	-0.06	0.86	0.59
155	|| orf19.7578 ||  ||  || Ortholog(s) have oligosaccharide binding activity, role in ER-associated ubiquitin-dependent protein catabolic process and Hrd1p ubiquitin ligase ERAD-L complex, luminal surveillance complex localization ||	1	0.31	0.74	1.46	1.16	0.61	-0.00	1.65	1.18
156	|| orf19.5205 ||  ||  || Protein of unknown function; Hap43-repressed gene ||	1	0.43	0.69	1.33	1.44	0.57	-0.10	1.79	1.31
157	|| orf19.4378 || PPH3 ||  || Putative catalytic subunit of protein phosphatase complex; functions with regulatory subunit Psy2p in dephosphorylation of Rad53p in response to DNA damage; dephosphorylates Rfa2p in G1 phase; ortholog of <i>S. cerevisiae</i> Pph3p ||	1	0.27	0.29	0.56	0.61	0.25	0.06	0.88	0.53
158	|| orf19.4975 || HYR1 ||  || GPI-anchored hyphal cell wall protein; macrophage-induced; repressed by neutrophils; resistance to killing by neutrophils, azoles; regulated by Rfg1, Efg1, Nrg1, Tup1, Cyr1, Bcr1, Hap43; Spider and flow model biofilm induced ||	1	0.42	0.39	0.73	0.62	0.28	0.01	0.83	0.57
159	|| orf19.5943 ||  ||  || Ortholog(s) have role in peroxisome organization and peroxisomal membrane localization ||	1	0.38	0.26	0.68	0.70	0.25	0.05	0.59	0.60
160	|| orf19.6440 ||  ||  || Ortholog(s) have ubiquitin-protein ligase activity, role in ubiquitin-dependent protein catabolic process and endoplasmic reticulum membrane, nuclear inner membrane localization ||	1	0.13	0.30	0.76	0.59	-0.00	-0.11	0.57	0.55
161	|| orf19.1162.1 ||  ||  || Ortholog(s) have Golgi apparatus localization ||	1	0.14	0.35	1.26	0.66	0.36	0.10	0.94	0.75
162	|| orf19.2411 || SYN8 ||  || Putative endosomal SNARE; role in protein transport; rat catheter and Spider biofilm induced ||	1	0.10	0.33	0.63	0.76	0.38	0.09	0.57	0.52
163	|| orf19.1433 ||  ||  || Protein of unknown function; Hap43-repressed; colony morphology-related gene regulation by Ssn6; Spider biofilm induced ||	1	0.12	0.51	0.82	0.97	0.41	0.20	0.72	0.67
164	|| orf19.6194 ||  ||  || Ortholog of <i>C. dubliniensis CD36</i> : Cd36_06640, <i>C. parapsilosis CDC317</i> : CPAR2_208220, <i>Candida tenuis NRRL Y-1498</i> : CANTEDRAFT_136902 and <i>Debaryomyces hansenii CBS767</i> : DEHA2F26730g ||	1	0.16	0.57	0.83	0.75	0.42	0.13	0.83	0.59
165	|| orf19.1277 ||  ||  || Protein of unknown function; Rgt1, Hap43-repressed; flow model biofilm induced; Spider biofilm induced ||	1	0.21	1.10	1.12	1.23	0.61	0.36	1.20	0.93
166	|| orf19.2046 || POT1-2 ||  || Putative peroxisomal 3-ketoacyl CoA thiolase; Hap43-repressed ||	1	0.11	0.61	0.62	0.79	0.21	0.05	0.54	0.40
167	|| orf19.7038 ||  ||  || Ortholog(s) have phosphatidylinositol-3-phosphate binding activity, role in protein targeting to vacuole and cytoplasm, nucleus localization ||	1	0.19	0.49	0.82	0.87	0.19	0.01	0.59	0.56
168	|| orf19.52 ||  ||  || Ortholog(s) have role in cellular iron ion homeostasis and mitochondrion localization ||	1	0.07	0.37	0.56	0.67	0.10	0.12	0.45	0.38
169	|| orf19.4591 || CAT2 ||  || Major carnitine acetyl transferase; intracellular acetyl-CoA transport; localized in peroxisomes and mitochondria; induced in macrophages; Hog1-repressed; stationary phase enriched; farnesol-upregulated in biofilm; Spider biofilm induced ||	1	0.13	0.45	0.58	0.71	0.16	0.11	0.63	0.51
170	|| orf19.346 || ALT1 ||  || Putative alanine transaminase; mutation confers hypersensitivity to 5-fluorocytosine (5-FC); rat catheter and flow model biofilm induced ||	1	0.25	0.66	1.00	0.85	0.11	-0.00	0.80	0.72
171	|| orf19.1591 || ERG10 ||  || Acetyl-CoA acetyltransferase; role in ergosterol biosynthesis; soluble in hyphae; changes in protein abundance associated with azole resistance; fluconazole or ketoconazole induced; macrophage-downregulated protein; GlcNAc-induced protein ||	1	0.22	0.56	1.02	0.78	0.11	0.00	0.74	0.50
172	|| orf19.6800 || POS5 ||  || Protein similar to S. cerevisiae Pos5p, a mitochondrial NADH kinase involved in the oxidative stress response; planktonic growth-induced gene; likely to be essential for growth, based on an insertional mutagenesis strategy ||	1	0.14	0.61	1.16	1.07	0.52	-0.10	0.95	0.90
173	|| orf19.1191 ||  ||  || Ortholog(s) have ubiquitin-protein ligase activity and role in ER-associated ubiquitin-dependent protein catabolic process ||	1	0.15	0.41	0.68	0.62	0.18	0.05	0.59	0.47
174	|| orf19.1756 || GPD1 ||  || Glycerol-3-phosphate dehydrogenase; glycerol biosynthesis; regulated by Efg1; regulated by Tsa1, Tsa1B under H2O2 stress conditions; Sflow model and Spider biofilm induced ||	1	0.10	0.34	0.74	0.55	0.23	0.05	0.57	0.48
175	|| orf19.775 ||  ||  || Ortholog of <i>C. dubliniensis CD36</i> : Cd36_04450, <i>C. parapsilosis CDC317</i> : CPAR2_105460, <i>Debaryomyces hansenii CBS767</i> : DEHA2D07128g and <i>Pichia stipitis Pignal</i> : PICST_80203 ||	1	0.12	0.63	1.29	1.09	0.39	0.13	0.89	0.72
176	|| orf19.5601 ||  ||  || Ortholog(s) have extracellular region localization ||	1	0.30	0.54	1.54	1.28	0.48	0.03	1.05	0.80
177	|| orf19.3749 || IFC3 ||  || Oligopeptide transporter; transcript induced by macrophage phagocytosis, BSA or peptides; fluconazole-induced; induced by Rim101 at pH 8; virulence-group-correlated expression; Hap43-repressed; Spider biofilm induced ||	1	0.18	0.74	2.56	1.84	0.42	0.20	1.84	1.74
178	|| orf19.3881 ||  ||  || Ortholog of <i>C. dubliniensis CD36</i> : Cd36_31790, <i>C. parapsilosis CDC317</i> : CPAR2_204900, <i>Candida tenuis NRRL Y-1498</i> : CANTEDRAFT_136864 and <i>Debaryomyces hansenii CBS767</i> : DEHA2F13200g ||	1	0.22	0.39	1.15	0.99	0.23	0.00	1.00	0.79
179	|| orf19.2913 ||  ||  || Predicted ORF from Assembly 19; merged with orf19.2911 in Assembly 20 ||	1	0.18	0.17	0.68	0.55	0.10	0.04	0.53	0.40
180	|| orf19.577 ||  ||  || Predicted protein tyrosine phosphatase; rat catheter biofilm induced ||	1	0.32	0.44	1.17	0.86	0.25	0.19	0.83	0.78
181	|| orf19.6045 ||  ||  || Putative phosphatidylserine decarboxylase; involved in phosphatidylethanolamine; Spider biofilm repressed ||	1	0.22	0.23	0.64	0.56	0.19	0.15	0.52	0.47
182	|| orf19.3734 || GEF2 ||  || Member of the voltage chloride channel family; Hap43p-repressed gene ||	1	0.32	0.36	1.01	0.93	0.45	0.13	1.00	0.80
183	|| orf19.4711 ||  ||  || Ortholog of <i>C. dubliniensis CD36</i> : Cd36_40890, <i>C. parapsilosis CDC317</i> : CPAR2_401100, <i>Candida tenuis NRRL Y-1498</i> : CANTEDRAFT_119698 and <i>Debaryomyces hansenii CBS767</i> : DEHA2G22154g ||	1	0.21	0.42	1.09	1.09	0.48	0.25	1.08	0.88
184	|| orf19.5727 ||  ||  || Ortholog of <i>C. dubliniensis CD36</i> : Cd36_64130, <i>C. parapsilosis CDC317</i> : CPAR2_601230, <i>Candida tenuis NRRL Y-1498</i> : CANTEDRAFT_115908 and <i>Debaryomyces hansenii CBS767</i> : DEHA2E12540g ||	1	0.22	0.62	1.43	1.28	0.44	0.22	1.31	1.01
185	|| orf19.6850 ||  ||  || Putative transcription factor with C3HC4 zinc finger DNA-binding motif; mutants are viable ||	1	0.09	0.41	0.80	0.75	0.23	0.07	0.75	0.77
186	|| orf19.1135 || CAS1 ||  || Putative transcription factor with Ku70/Ku80 beta-barrel DNA-binding motif; involved in telomerase regulation and telomere protection; mutation causes marginal increase in caspofungin sensitivity ||	1	0.11	0.25	0.62	0.57	0.21	0.06	0.48	0.59
187	|| orf19.5752 ||  ||  || Ortholog(s) have ubiquitin-protein ligase activity, role in SCF-dependent proteasomal ubiquitin-dependent protein catabolic process and SCF ubiquitin ligase complex localization ||	1	0.10	0.37	0.87	0.97	0.26	0.22	0.77	0.77
188	|| orf19.1614 || MEP1 ||  || Ammonium permease; Mep1 more efficient permease than Mep2, Mep2 has additional regulatory role; 11 predicted transmembrane regions; low mRNA abundance; hyphal downregulated; flow model biofilm induced ||	1	0.12	1.17	2.72	2.18	0.24	0.14	1.56	1.79
189	|| orf19.5114 ||  ||  || Sorting nexin; role in maintaining late-Golgi resident enzymes in their proper location by recycling molecules from the prevacuolar compartment; Spider biofilm induced ||	1	-0.03	0.44	1.00	1.11	0.13	0.09	0.99	0.72
190	|| orf19.97 || CAN1 ||  || Basic amino acid permease; complements lysine transport mutation; 10 predicted transmembrane regions, 3 predicted N-glycosylation sites; phagocytosis by macrophages induces transcript; rat catheter, Spider and flow model biofilm induced ||	1	0.66	0.78	2.45	1.66	0.26	0.14	1.31	1.24
191	|| orf19.5095 ||  ||  || Putative oxysterol-binding protein; caspofungin induced; possibly an essential gene, disruptants not obtained by UAU1 method ||	1	0.17	0.46	1.16	0.91	0.17	0.05	0.46	0.49
192	|| orf19.3233 || HSE1 ||  || ESCRT-0 complex subunit; SH3-domain-containing protein ||	1	0.23	0.26	0.91	0.58	0.20	0.26	0.58	0.72
193	|| orf19.192 ||  ||  || Ortholog of <i>C. dubliniensis CD36</i> : Cd36_19320, <i>C. parapsilosis CDC317</i> : CPAR2_209670, <i>Candida tenuis NRRL Y-1498</i> : CANTEDRAFT_113478 and <i>Debaryomyces hansenii CBS767</i> : DEHA2C15136g ||	1	0.33	0.53	0.70	0.84	0.27	-0.12	0.53	0.51
194	|| orf19.4763 ||  ||  || Protein of unknown function; possibly membrane bound; mutants are viable; rat catheter biofilm repressed ||	1	0.66	0.99	1.43	1.63	0.73	0.17	1.23	1.02
195	|| orf19.3407 || RAD18 ||  || Putative transcription factor with zinc finger DNA-binding motif; Hap43p-repressed gene ||	1	0.37	0.48	0.59	0.67	0.44	-0.02	0.55	0.27
196	|| orf19.3461 ||  ||  || Protein of unknown function; oxidative stress-induced via Cap1; induced by alpha pheromone in SpiderM medium ||	1	0.54	0.64	1.07	0.99	0.51	0.41	0.51	1.09
197	|| orf19.3461 ||  ||  || Protein of unknown function; oxidative stress-induced via Cap1; induced by alpha pheromone in SpiderM medium ||	1	0.54	0.64	1.07	0.99	0.51	0.41	0.51	1.09
198	|| orf19.919 ||  ||  || Predicted ORF from Assembly 19; orf19.918 and orf19.919 may be a single ORF encoding a putative transporter of the PDR subfamily of the ABC protein family; merged with orf19.918 in Assembly 20 ||	1	0.88	1.08	2.05	2.29	0.47	0.61	1.18	2.08
199	|| orf19.3615 ||  ||  || Protein of unknown function; induced in core caspofungin response; expression upregulated in an ssr1 null mutant; induced by nitric oxide independent of Yhb1p ||	1	0.35	0.68	1.22	1.52	0.62	0.37	0.76	0.90
200	|| orf19.2905 ||  ||  || Ortholog of <i>Candida albicans WO-1</i> : CAWG_03194 ||	1	0.16	0.67	0.84	1.04	0.54	0.28	0.41	0.63
201	|| orf19.827 ||  ||  || Ortholog of <i>C. dubliniensis CD36</i> : Cd36_18620, <i>C. parapsilosis CDC317</i> : CPAR2_212480, <i>Candida tenuis NRRL Y-1498</i> : CANTEDRAFT_115371 and <i>Debaryomyces hansenii CBS767</i> : DEHA2D06798g ||	1	0.47	0.94	0.89	1.54	0.43	0.51	0.56	0.81
202	|| orf19.802 || UGA1 ||  || Putative GABA transaminase; transcription regulated by Mig1 and Tup1; stationary phase enriched protein; rat catheter and Spider biofilm induced ||	1	0.21	0.86	0.84	0.60	0.09	0.20	0.51	0.33
203	|| orf19.6109 || TUP1 ||  || Transcriptional corepressor; represses filamentous growth; regulates switching; role in germ tube induction, farnesol response; in repression pathways with Nrg1, Rfg1; farnesol upregulated in biofilm; rat catheter, Spider biofilm repressed ||	1	0.27	0.79	0.73	0.66	0.02	0.39	0.43	0.53
204	|| orf19.1443 || PLB4 ||  || Putative phospholipase B; merged with orf19.1442 in Assembly 20 ||	1	0.48	0.94	1.01	0.94	0.28	0.37	0.55	0.58
205	|| orf19.7380 ||  ||  || Has domain(s) with predicted nucleic acid binding, nucleotide binding activity ||	1	0.54	1.04	1.28	1.18	0.37	0.27	0.71	0.71
206	|| orf19.6443 ||  ||  || Protein with an enoyl-CoA hydratase related domain; Spider biofilm induced ||	1	0.31	0.92	1.09	0.93	0.21	0.24	0.59	0.78
207	|| orf19.1237 || ARO9 ||  || Aromatic transaminase; Ehrlich fusel oil pathway of aromatic alcohol biosynthesis; Rim101-dependent pH-regulation (alkaline induced); Hap43-induced gene ||	1	0.59	1.76	2.54	2.06	0.61	0.90	1.10	1.48
208	|| orf19.1237 || ARO9 ||  || Aromatic transaminase; Ehrlich fusel oil pathway of aromatic alcohol biosynthesis; Rim101-dependent pH-regulation (alkaline induced); Hap43-induced gene ||	1	0.59	1.76	2.54	2.06	0.61	0.90	1.10	1.48
209	|| orf19.4424 || PHO100 ||  || Putative inducible acid phosphatase; DTT-extractable and observed in culture supernatant in low-phosphate conditions; slight effect on murine virulence; virulence-group-correlated expression; N-glycosylated; F-12/CO2 early biofilm induced ||	1	0.60	1.78	2.27	1.42	0.67	0.59	0.98	1.21
210	|| orf19.7131 ||  ||  || Butyrobetaine dioxygenase, the fourth enzyme of the carnitine biosynthesis pathway ||	1	0.53	0.82	1.54	0.92	0.41	0.41	1.03	0.66
211	|| orf19.2151 || NAG6 ||  || Protein required for wild-type mouse virulence and wild-type cycloheximide resistance; putative GTP-binding motif; similar to S. cerevisiae Yor165Wp; in gene cluster that encodes enzymes of GlcNAc catabolism; no human or murine homolog ||	1	0.26	0.43	0.77	0.59	0.19	0.15	0.45	0.33
212	|| orf19.2515 ||  ||  || ZZ-type zinc finger protein; rat catheter and Spider biofilm induced ||	1	0.45	2.01	3.24	2.17	0.85	0.41	1.87	1.67
213	|| orf19.467 || WOR3 ||  || Transcription factor; modulator of white-opaque switch; induced in opaque cells; promoter bound by Wor1; overexpression at 25 degr shifts cells to opaque state; deletion stabilizes opaque cells at higher temperatures; Spider biofilm induced ||	1	0.36	1.03	1.48	0.81	0.41	0.19	0.71	0.72
214	|| orf19.1763 || IFR1 ||  || Predicted oxidoreductase/dehydrogenase; induced by nitric oxide; rat catheter and Spider biofilm induced ||	1	0.67	1.72	2.77	1.52	0.89	0.10	1.39	1.24
215	|| orf19.7567 ||  ||  || Protein of unknown function; induced by alpha pheromone in SpiderM medium ||	1	0.44	0.84	1.89	1.44	0.73	0.20	1.03	1.01
216	|| orf19.6148 ||  ||  || Homolog of nuclear distribution factor NudE, NUDEL; regulates dynein targeting to microtubule plus ends; flow model biofilm repressed ||	1	0.47	0.89	2.15	1.57	0.83	0.48	0.94	0.83
217	|| orf19.2065 ||  ||  || Ortholog(s) have role in allantoin catabolic process and cytosol, nucleus localization ||	1	0.19	0.64	0.91	0.56	0.42	0.09	0.48	0.68
218	|| orf19.971 || SKN7 ||  || Putative homolog of S. cerevisiae Skn7p, which is predicted to be a response regulator protein in a phosphorelay signal transduction pathway; required for normal hydrogen peroxide resistance ||	1	0.22	0.61	0.73	0.80	0.14	-0.04	0.39	0.60
219	|| orf19.1482 || HSK3 ||  || Subunit of the Dam1 (DASH) complex, which acts in chromosome segregation by coupling kinetochores to spindle microtubules; expression regulated during planktonic growth ||	1	-0.02	0.53	0.70	0.88	-0.11	0.05	0.35	0.50
220	|| orf19.6709 ||  ||  || Predicted alpha/beta hydrolase; Spider biofilm induced ||	1	0.04	0.52	0.66	0.68	-0.24	0.15	0.34	0.34
221	|| orf19.1655 || PXP2 ||  || Putative acyl-CoA oxidase; enzyme of fatty acid beta-oxidation; induced during macrophage infection; opaque specific transcript; putative peroxisome targeting signal; Spider biofilm induced ||	1	0.56	1.35	1.80	1.72	-0.32	0.39	1.02	1.16
222	|| orf19.7538 ||  ||  || DNA helicase involved in rDNA replication; Spider biofilm repressed ||	1	0.27	0.62	0.62	0.75	0.20	0.22	0.43	0.57
223	|| orf19.7229 || IML2 ||  || Protein of unknown function; early-stage flow model biofilm induced; Hap43-repressed; Spider biofilm repressed ||	1	0.08	0.60	0.81	0.82	0.30	0.20	0.53	0.54
224	|| orf19.4690 ||  ||  || NRAMP metal ion transporter domain-containing protein; induced by nitric oxide independent of Yhb1; flow model biofilm induced; rat catheter biofilm repressed ||	1	0.25	2.33	3.49	3.36	0.94	1.29	1.75	2.75
225	|| orf19.2190 || VRP1 ||  || Verprolin-related protein involved in actin cytoskeleton organization and polarized morphogenesis; interacts with Wal1p and Myo5p; downregulated upon adherence to polystyrene ||	1	0.06	1.18	1.17	1.28	0.27	0.31	0.66	1.05
226	|| orf19.4699 ||  ||  || Putative phospholipase of patatin family; similar to S. cerevisiae Tgl3p; predicted Kex2p substrate ||	1	0.04	1.15	1.09	1.34	0.32	0.41	0.86	1.03
227	|| orf19.2163 ||  ||  || Ortholog(s) have cytosol localization ||	1	0.01	0.75	0.82	0.93	0.09	0.27	0.66	0.71
228	|| orf19.6469 ||  ||  || Predicted ORF in retrotransposon Tca11 with similarity to the Gag-Pol region of retrotransposons, which encodes nucleocapsid-like protein, reverse transcriptase, protease, and integrase ||	1	0.08	0.60	0.73	0.75	0.14	0.24	0.57	0.73
229	|| orf19.6838 ||  ||  || Putative protein of unknown function, transcript upregulated in clinical isolates from HIV+ patients with oral candidiasis; Spider biofilm induced ||	1	0.11	0.82	0.94	0.97	0.20	0.37	0.70	0.99
230	|| orf19.2691 ||  ||  || Planktonic growth-induced gene ||	1	0.55	2.42	2.43	3.19	0.65	1.21	2.13	2.71
231	|| orf19.1424 ||  ||  || Predicted membrane transporter, member of the oxalate:formate antiporter (OFA) family, major facilitator superfamily (MFS) ||	1	0.14	0.71	1.08	1.17	0.17	0.55	0.86	0.94
232	|| orf19.5777 ||  ||  || Protein of unknown function; F-12/CO2 early biofilm induced ||	1	0.22	1.05	1.79	1.84	0.34	0.72	1.38	1.54
233	|| orf19.4287 ||  ||  || Putative oxidoreductase; Hap43-repressed gene; clade-associated gene expression ||	1	0.11	1.05	1.67	1.90	0.09	0.42	1.21	1.61
234	|| orf19.3658 ||  ||  || Ortholog(s) have role in protein folding in endoplasmic reticulum and Golgi apparatus, integral to endoplasmic reticulum membrane, mitochondrion localization ||	1	0.02	0.57	0.57	0.81	-0.02	0.33	0.50	0.62
235	|| orf19.2050 ||  ||  || Ortholog(s) have sterol esterase activity, role in cellular lipid metabolic process, sterol metabolic process and fungal-type vacuole, integral to membrane, lipid particle localization ||	1	-0.14	0.67	0.91	0.91	0.03	0.08	0.76	1.03
236	|| orf19.2107 || MUQ1 ||  || Putative choline phosphate cytidylyltransferase/phosphoethanolamine cytidylyltransferase; repressed in hyphae compared vs yeast; Hap43-repressed; flow model biofilm induced; Spider biofilm repressed ||	1	-0.10	0.57	0.65	0.59	0.11	0.10	0.36	0.51
237	|| orf19.3508 ||  ||  || Putative protein of unknown function; stationary phase enriched protein ||	1	-0.25	0.98	1.17	1.00	-0.00	0.30	0.75	1.23
238	|| orf19.3973 ||  ||  || Ortholog of Hua1, a zinc finger domain protein with sequence similarity to Type I J-proteins; flow model biofilm induced ||	1	-0.16	0.98	1.05	1.05	-0.06	0.17	0.64	1.01
239	|| orf19.2691 ||  ||  || Planktonic growth-induced gene ||	1	-0.07	1.47	1.94	2.04	-0.11	0.43	1.11	1.66
240	|| orf19.1723 ||  ||  || Ortholog(s) have role in response to purine-containing compound and cytoplasm, nucleus localization ||	1	-0.12	0.45	0.55	0.58	-0.07	0.16	0.32	0.45
241	|| orf19.6956 || DAL9 ||  || Putative allantoate permease; fungal-specific (no human or murine homolog) ||	1	-0.22	0.66	1.01	0.71	-0.10	0.24	0.41	0.76
242	|| orf19.296 ||  ||  || Ortholog of <i>C. dubliniensis CD36</i> : Cd36_82980, <i>C. parapsilosis CDC317</i> : CPAR2_102360, <i>Candida tenuis NRRL Y-1498</i> : cten_CGOB_00165 and <i>Debaryomyces hansenii CBS767</i> : DEHA2G00990g ||	1	-0.11	1.24	1.75	1.21	-0.10	0.05	1.08	1.15
243	|| orf19.539 || LAP3 ||  || Putative aminopeptidase; positively regulated by Sfu1; clade-associated gene expression; virulence-group-correlated expression; induced by alpha pheromone in SpiderM medium; Hap43-induced; Spider and flow model biofilm induced ||	1	0.09	1.03	1.38	1.04	0.23	0.03	0.87	1.01
244	|| orf19.2791 || BBC1 ||  || Putative SH3-domain-containing protein ||	1	0.13	0.66	0.73	0.61	0.05	0.01	0.36	0.43
245	|| orf19.5342 ||  ||  || Ortholog(s) have cytosol, extracellular region, fungal-type vacuole, nucleus localization ||	1	0.05	0.62	0.70	0.62	-0.06	0.10	0.37	0.39
246	|| orf19.3150 || GRE2 ||  || Putative reductase; Nrg1 and Tup1-regulated; benomyl- and hyphal-induced; macrophage/pseudohyphal-repressed; repressed by low iron; possibly involved in osmotic stress response; stationary phase enriched protein; Spider biofilm induced ||	1	-0.08	0.59	0.74	0.55	0.01	0.23	0.30	0.46
247	|| orf19.4716 || GDH3 ||  || NADP-glutamate dehydrogenase; Nrg1, Plc1 regulated; hypha, hypoxia, Efg1-repressed; Rim101-induced at pH 8; GlcNAc, ciclopirox, ketoconazole induced; exp and stationary phase protein; Spider biofilm repressed; rat catheter biofilm induced ||	1	-0.05	0.70	0.95	0.64	0.05	0.37	0.22	0.64
248	|| orf19.2568 || IFU5 ||  || Predicted membrane protein; estradiol-induced; upregulation associated with CDR1 and CDR2 overexpression or fluphenazine; putative drug-responsive regulatory site; similar to S. cerevisiae Wwm1p; Hap43-repressed; Spider biofilm repressed ||	1	0.09	0.73	1.13	0.78	0.17	0.29	0.41	0.71
249	|| orf19.5614 ||  ||  || Putative ribonuclease H1; possibly an essential gene, disruptants not obtained by UAU1 method; flow model biofilm induced; Spider biofilm induced ||	1	-0.08	1.37	1.28	1.65	-0.12	0.99	0.67	1.19
250	|| orf19.886 || PAN1 ||  || Essential protein involved in endocytosis and polarized growth; ortholog of S. cerevisiae Pan1, which is a part of a complex that regulates actin cytoskeleton; Spider biofilm repressed ||	1	0.10	0.87	0.85	0.89	-0.07	0.41	0.43	0.77
251	|| orf19.7080 || LEU2 ||  || Isopropyl malate dehydrogenase; leucine biosynthesis; induced by human whole blood or PMNs; protein level decreases in stationary phase; GlcNAc-induced protein; flow model biofilm repressed ||	1	0.06	0.63	0.60	0.56	-0.20	0.29	0.19	0.41
252	|| orf19.6754 ||  ||  || Protein of unknown function; Spider biofilm induced ||	1	-0.08	0.21	0.60	0.54	0.11	0.14	0.33	0.34
253	|| orf19.5875 || VAM3 ||  || Predicted target membrane receptor (t-SNARE) involved in vacuolar transport, endocytosis, and secretion; required for biofilm formation in RPMI-1640 and for virulence; rat catheter biofilm repressed ||	1	-0.18	0.61	0.69	0.75	0.55	0.05	0.60	0.99
254	|| orf19.3021 ||  ||  || Putative protein of unknown function; Hap43-repressed gene; Spider biofilm induced ||	1	-0.39	0.58	0.90	0.97	0.46	0.07	0.60	0.79
255	|| orf19.5961 ||  ||  || Ortholog(s) have role in proteasome regulatory particle assembly, proteolysis and cytosol, nucleus, proteasome regulatory particle localization ||	1	-0.14	0.28	0.55	0.54	0.37	-0.08	0.63	0.41
256	|| orf19.6638 || PTC4 ||  || Type PP2C serine/threonine phosphatase; localized to mitochondria; mutation causes sensitivity to sodium, potassium and azole drugs; decreased expression in hyphae compared to yeast-form cells ||	1	-0.14	0.09	0.67	0.74	0.24	0.06	0.56	0.58
257	|| orf19.89 || PEX7 ||  || Ortholog(s) have peroxisome matrix targeting signal-2 binding activity, role in fatty acid metabolic process, protein import into peroxisome matrix, docking and cytosol, nucleus, peroxisome localization ||	1	-0.12	0.37	0.48	0.72	0.21	0.01	0.74	0.62
258	|| orf19.6852 ||  ||  || Ortholog of Rmd6 involved in S. cerevisiae sporulation; flow model biofilm induced ||	1	-0.03	0.18	0.52	0.71	0.39	0.27	0.68	0.55
259	|| orf19.2107.1 || STF2 ||  || Protein involved in ATP biosynthesis; repressed in hyphae; repressed by Efg1, Hap43; transcript upregulated in clinical isolates from HIV+ patients with oral candidiasis; rat catheter, flow model and Spider biofilm induced ||	1	-0.00	0.36	0.43	0.63	0.25	0.19	0.64	0.62
260	|| orf19.719 ||  ||  || Ortholog(s) have ubiquitin-protein ligase activity ||	1	0.10	0.63	0.76	1.26	0.37	0.28	0.94	0.88
261	|| orf19.1940 ||  ||  || Ortholog(s) have role in cellular response to cadmium ion, detoxification of cadmium ion, ubiquinone biosynthetic process and mitochondrial inner membrane localization ||	1	-0.03	0.44	0.64	1.08	0.30	0.36	0.68	0.84
262	|| orf19.1940 ||  ||  || Ortholog(s) have role in cellular response to cadmium ion, detoxification of cadmium ion, ubiquinone biosynthetic process and mitochondrial inner membrane localization ||	1	0.04	0.24	0.36	0.93	0.24	0.29	0.59	0.76
263	|| orf19.6816 ||  ||  || Putative xylose and arabinose reductase; flow model biofilm induced; Spider biofilm repressed ||	1	-0.01	0.02	0.34	0.71	0.26	0.17	0.67	0.57
264	|| orf19.6816 ||  ||  || Putative xylose and arabinose reductase; flow model biofilm induced; Spider biofilm repressed ||	1	-0.00	0.11	0.59	0.76	0.22	0.17	0.78	0.69
265	|| orf19.5640 || PEX5 ||  || Pex5p family protein; required for PTS1-mediated peroxisomal protein import, fatty acid beta-oxidation; similar to S. cerevisiae Pas10p peroxisomal targeting receptor; macrophage/pseudohyphal-repressed; Hap43p-repressed ||	1	0.04	-0.01	0.40	0.56	0.11	0.02	0.64	0.57
266	|| orf19.5751 || ORM1 ||  || Putative endoplasmic reticulum membrane protein; Hap43p-repressed gene; mutation confers hypersensitivity to aureobasidin A ||	1	0.22	0.21	1.02	1.26	0.47	0.41	0.80	0.59
267	|| orf19.6624 ||  ||  || Ortholog(s) have GTPase activator activity and clathrin-coated vesicle, endosome localization ||	1	0.64	0.38	0.92	0.81	0.31	0.29	1.05	0.56
268	|| orf19.2204.2 || RHO2 ||  || Ortholog(s) have GTPase activity ||	1	0.58	0.30	1.25	0.61	0.37	0.32	0.90	0.47
269	|| orf19.5815 || SCT2 ||  || Putative glycerol-3-phosphate acyltransferase; fungal-specific (no human or murine homolog) ||	1	0.56	0.17	1.31	0.74	0.43	0.22	0.85	0.59
270	|| orf19.4658 ||  ||  || RING finger and CHY zinc finger domain-containing protein; mutant are viable ||	1	0.66	0.49	1.73	1.38	0.80	0.42	0.98	0.58
271	|| orf19.6068 || SVF1 ||  || Putative survival factor; stationary phase enriched protein; fluconazole-induced; regulated by Gcn4p; repressed in response to amino acid starvation (3-AT treatment); fungal-specific (no human or murine homolog) ||	1	0.39	0.11	0.92	0.69	0.54	0.19	0.61	0.53
272	|| orf19.288 || MET13 ||  || Putative methionine biosynthesis protein; ketoconazole-induced; amphotericin B repressed; Spider biofilm repressed ||	1	0.70	0.29	1.42	1.24	0.79	0.49	1.24	0.84
273	|| orf19.3804 ||  ||  || Protein of unknown function; filament induced ||	1	0.43	0.22	0.89	0.73	0.51	0.29	0.61	0.46
274	|| orf19.3921 ||  ||  || Ortholog(s) have cell division site, cell tip, cytosol, nucleus localization ||	1	0.66	0.26	1.50	1.11	0.64	0.54	1.02	0.75
275	|| orf19.4459 ||  ||  || Predicted heme-binding stress-related protein; Tn mutation affects filamentous growth; induced during chlamydospore formation in C. albicans and C. dubliniensis; Spider biofilm induced ||	1	0.67	0.24	1.81	1.80	1.10	0.76	1.24	0.98
276	|| orf19.1069 || RPN4 ||  || C2H2 transcription factor; putative regulator of proteasome genes; DNA recognition sequence (GAAGGCAAAA) enriched in regions upstream of proteasome genes; induced in core stress response; Hap43-induced; Spider biofilm induced ||	1	0.51	0.17	1.01	1.11	0.60	0.38	0.78	0.69
277	|| orf19.951 ||  ||  || Protein of unknown function; transcript repressed upon yeast-hyphal switch; fluconazole-induced; Hap43-repressed; flow model biofilm induced ||	1	0.35	0.43	1.04	1.38	0.87	0.17	1.26	0.62
278	|| orf19.7457 ||  ||  || Protein with Mob2p-dependent hyphal regulation ||	1	0.44	0.64	1.21	1.41	0.77	0.31	1.44	0.86
279	|| orf19.6832 ||  ||  || Protein of unknown function; regulated by Sef1p-, Sfu1p-, and Hap43p ||	1	0.30	0.39	0.82	0.87	0.53	0.16	0.91	0.67
280	|| orf19.6970 ||  ||  || Ortholog of <i>C. dubliniensis CD36</i> : Cd36_85310, <i>C. parapsilosis CDC317</i> : CPAR2_807370, <i>Candida tenuis NRRL Y-1498</i> : CANTEDRAFT_115544 and <i>Debaryomyces hansenii CBS767</i> : DEHA2D11770g ||	1	0.87	0.95	1.94	1.94	1.40	0.47	2.24	1.49
281	|| orf19.4292 ||  ||  || Ortholog(s) have SNAP receptor activity, role in Golgi to vacuole transport, vacuole inheritance and Golgi apparatus, endosome localization ||	1	0.29	0.11	0.87	0.88	0.53	0.08	0.91	0.59
282	|| orf19.5248 || MSO1 ||  || Putative secretory protein involved in S. cerevisiae sporulation; repressed during pseudohyphal growth in the presence of lysed macrophages; Hap43-repressed; Spider biofilm induced ||	1	0.43	0.37	1.61	1.52	1.09	0.35	1.53	1.18
283	|| orf19.6437 || CDC23 ||  || Similar to anaphase-promoting complex component; possibly transcriptionally regulated by Tac1p ||	1	0.17	0.16	0.70	0.62	0.35	0.08	0.57	0.45
284	|| orf19.6905 ||  ||  || Ortholog of <i>S. cerevisiae</i> : YNL011C, <i>C. glabrata CBS138</i> : CAGL0H03619g, <i>C. dubliniensis CD36</i> : Cd36_71090, <i>C. parapsilosis CDC317</i> : CPAR2_300420 and <i>Candida tenuis NRRL Y-1498</i> : CANTEDRAFT_111980 ||	1	0.09	0.18	0.63	0.56	0.33	0.01	0.48	0.35
285	|| orf19.5249 ||  ||  || Ortholog(s) have role in ascospore formation, meiosis and cytosol, nucleus localization ||	1	0.29	0.51	1.40	0.93	0.66	0.19	1.00	0.63
286	|| orf19.2174 || RAD57 ||  || Putative DNA recombination and repair protein; induced by interaction with macrophage; transcript is regulated by Nrg1, Mig1, and Tup1; essential protein; S. cerevisiae ortholog is essential ||	1	0.35	0.42	1.17	0.76	0.68	0.09	0.90	0.55
287	|| orf19.4246 ||  ||  || Protein with similarity to S. cerevisiae Ykr070w; Tn mutation affects filamentation; Hog1-repressed; colony morphology-related gene regulation by Ssn6p; induced during cell wall regeneration; possibly essential ||	1	0.50	0.41	1.16	0.60	0.68	0.21	0.89	0.48
288	|| orf19.4726 ||  ||  || Ortholog(s) have calcium ion binding, enzyme activator activity ||	1	0.38	0.23	1.01	0.60	0.65	0.26	0.82	0.50
289	|| orf19.996 ||  ||  || Protein with a predicted leucine-rich repeat domain; possibly an essential gene, disruptants not obtained by UAU1 method ||	1	0.41	0.35	1.32	0.91	0.90	0.08	1.13	0.79
290	|| orf19.135 || EXO84 ||  || Predicted subunit of the exocyst complex, involved in exocytosis; localizes to a crescent on the surface of the hyphal tip ||	1	0.44	0.21	1.07	0.67	0.75	-0.02	0.74	0.56
291	|| orf19.4982 ||  ||  || Has domain(s) with predicted role in lipid metabolic process ||	1	0.80	0.65	1.60	0.98	0.91	0.14	1.42	0.84
292	|| orf19.1161 || PLD1 ||  || Phospholipase D1; required for phosphatidic acid and for most diacylglycerol production; required for wild-type mouse virulence, but not rat oral virulence; mutant defect in hyphal growth on solid substrates; similar to S. cerevisiae Spo14p ||	1	0.42	0.29	0.87	0.56	0.43	0.12	0.78	0.45
293	|| orf19.5644 ||  ||  || Ortholog(s) have role in ascospore wall assembly, spore membrane bending pathway and cytoplasm, prospore membrane localization ||	1	0.96	0.69	1.65	1.10	0.79	0.29	1.39	0.94
294	|| orf19.2862 || RIB1 ||  || Putative GTP cyclohydrolase II; enzyme of riboflavin biosynthesis; fungal-specific (no human or murine homolog); regulated by Sef1p-, Sfu1p-, and Hap43p ||	1	0.33	0.40	0.86	0.62	0.36	0.08	0.73	0.53
295	|| orf19.5798 || LIG4 ||  || DNA ligase; mRNA detected in yeast-form and pseudohyphal cells, induced upon hyphal induction; suppresses S. cerevisiae ime1-1 mutant IME2 transcription defect; required for wild-type filamentous growth and wild-type pathogenesis ||	1	0.74	0.61	1.73	1.28	0.91	0.29	1.39	0.95
296	|| orf19.7092 ||  ||  || Putative NAD dependent epimerase/dehydratase family protein; Spider biofilm repressed ||	1	0.33	0.31	0.96	0.79	0.50	0.14	0.80	0.59
297	|| orf19.4031 ||  ||  || Ortholog(s) have cytoplasm localization ||	1	0.68	0.49	1.72	1.24	0.98	0.28	1.75	1.11
298	|| orf19.6498 ||  ||  || Ortholog(s) have role in RNA polymerase II complex localization to nucleus, RNA polymerase III complex localization to nucleus and DNA-directed RNA polymerase II, holoenzyme, cytoplasm localization ||	1	0.39	0.20	0.82	0.58	0.49	0.05	0.81	0.53
299	|| orf19.3411 ||  ||  || Ortholog(s) have role in cellular bud site selection and cytosol, nucleus localization ||	1	0.44	0.15	0.80	0.63	0.38	-0.01	0.84	0.48
300	|| orf19.393 || APS3 ||  || Component of the adaptor complex AP-3, which is involved in vacuolar protein sorting ||	1	0.37	0.24	0.88	0.60	0.40	0.01	0.86	0.44
301	|| orf19.3848 ||  ||  || Ortholog of <i>C. dubliniensis CD36</i> : Cd36_31420, <i>C. parapsilosis CDC317</i> : CPAR2_205100, <i>Debaryomyces hansenii CBS767</i> : DEHA2G10648g and <i>Pichia stipitis Pignal</i> : PICST_32997 ||	1	1.29	0.82	2.66	1.83	1.00	0.18	2.67	1.48
302	|| orf19.2836 ||  ||  || Protein with similarity to carbonic anhydrases ||	1	1.34	0.73	2.41	1.75	1.03	0.39	2.52	1.59
303	|| orf19.6912 ||  ||  || Putative ethanolamine kinase ||	1	0.52	0.18	1.35	0.66	0.61	0.18	1.07	0.73
304	|| orf19.3318 ||  ||  || Ortholog(s) have cytoplasm localization ||	1	0.62	0.20	1.62	0.97	0.72	0.02	1.39	0.69
305	|| orf19.5492 ||  ||  || Ortholog(s) have mRNA binding, pre-mRNA 5'-splice site binding activity, role in mRNA 5'-splice site recognition and U1 snRNP, U2-type prespliceosome, commitment complex localization ||	1	0.24	0.05	1.02	0.83	0.45	0.31	1.04	0.56
306	|| orf19.35 ||  ||  || Predicted kinase; rat catheter, flow model, Spider biofilm induced ||	1	0.39	0.09	1.07	0.89	0.47	0.18	1.10	0.72
307	|| orf19.3135 ||  ||  || Ortholog(s) have protein binding, bridging activity and role in ER-associated ubiquitin-dependent protein catabolic process, lipid particle organization ||	1	0.37	0.21	1.00	0.83	0.34	0.04	1.08	0.75
308	|| orf19.2703 ||  ||  || Specificity factor required for ubiquitination and sorting of specific cargo proteins at the multivesicular body; ortholog of S. cerevisiae Ear1; transcript regulated by iron; Ssr1-represssed; Spider biofilm induced ||	1	0.32	0.19	1.06	0.78	0.17	0.09	1.06	0.72
309	|| orf19.90 ||  ||  || Ortholog(s) have cytoplasm localization ||	1	0.34	0.10	2.29	1.77	0.96	0.10	1.97	1.17
310	|| orf19.4077 || MIT1 ||  || Mannosylinositol phosphorylceramide (MIPC) synthase catalytic subunit; sphingolipid biosynthesis; fluconazole, caspofungin induced; macrophage-repressed; Spider biofilm induced ||	1	0.20	0.16	1.16	0.91	0.46	0.01	0.82	0.40
311	|| orf19.2772 || HOS3 ||  || Histone deacetylase; similar to S. cerevisiae Hos3p; greater expression and longer mRNA in white cells, compared to opaque cells; has conserved deacetylation motif ||	1	0.14	0.19	0.65	0.56	0.37	-0.09	0.52	0.29
312	|| orf19.4206 ||  ||  || Ortholog(s) have crossover junction endodeoxyribonuclease activity ||	1	0.42	0.24	1.12	1.16	0.66	-0.04	0.93	0.49
313	|| orf19.2943 ||  ||  || Predicted ORF from Assembly 19; merged with orf19.2942 in Assembly 20 ||	1	0.61	0.05	1.24	1.21	0.80	-0.13	1.19	0.77
314	|| orf19.1412 ||  ||  || Ortholog of <i>C. dubliniensis CD36</i> : Cd36_44020, <i>C. parapsilosis CDC317</i> : CPAR2_302330, <i>Candida tenuis NRRL Y-1498</i> : CANTEDRAFT_105448 and <i>Debaryomyces hansenii CBS767</i> : DEHA2C10582g ||	1	0.46	0.20	0.53	0.60	0.45	-0.04	0.87	0.59
315	|| orf19.2108 || SOD6 ||  || Copper- and zinc-containing superoxide dismutase; gene family includes SOD1, SOD4, SOD5, and SOD6; gene may contain an intron; Hap43-repressed; flow model and rat catheter biofilm induced ||	1	0.91	0.30	0.89	1.05	0.72	0.19	1.38	0.75
316	|| orf19.4723 || FAD1 ||  || Ortholog(s) have ATP binding, FMN adenylyltransferase activity, magnesium ion binding activity, role in FAD biosynthetic process and cytosol, nucleus localization ||	1	0.60	0.30	0.75	0.65	0.52	0.25	1.11	0.60
317	|| orf19.537 ||  ||  || Ortholog of <i>C. dubliniensis CD36</i> : Cd36_29810, <i>C. parapsilosis CDC317</i> : CPAR2_206030, <i>Candida tenuis NRRL Y-1498</i> : CANTEDRAFT_102086 and <i>Debaryomyces hansenii CBS767</i> : DEHA2F14014g ||	1	0.84	0.42	0.90	0.64	0.80	0.50	1.33	0.51
318	|| orf19.2452 ||  ||  || Protein of unknown function; induced in high iron; repressed in core caspofungin response; ketoconazole-repressed; colony morphology-related gene regulation by Ssn6; possibly subject to Kex2 processing ||	1	1.13	0.34	1.08	0.93	1.11	0.57	1.42	0.77
319	|| orf19.1592 ||  ||  || Protein of unknown function; Spider biofilm induced ||	1	0.91	0.30	1.10	0.64	1.01	0.37	1.16	0.56
320	|| orf19.6357 ||  ||  || Ortholog(s) have role in mitotic DNA integrity checkpoint, negative regulation of protein import into nucleus during spindle assembly checkpoint, nucleocytoplasmic transport ||	1	1.13	0.29	1.01	0.68	1.06	0.32	1.38	0.52
321	|| orf19.910 || PRP3 ||  || Predicted splicing factor, component of the U4/U6-U5 snRNP complex; Hap43-induced gene; rat catheter biofilm induced ||	1	0.76	0.22	0.75	0.76	0.93	0.34	1.21	0.73
322	|| orf19.4731 ||  ||  || Ortholog(s) have role in CVT pathway, intra-Golgi vesicle-mediated transport and Golgi transport complex localization ||	1	0.52	0.01	0.88	0.71	0.80	0.18	0.95	0.48
323	|| orf19.4897 || SFH5 ||  || Putative phosphatidylinositol transporter; rat catheter and Spider biofilm repressed ||	1	0.92	0.36	1.41	1.14	1.20	0.44	1.43	0.86
324	|| orf19.1377 || IPK2 ||  || Putative inositol polyphosphate multikinase; moderately induced at 42 deg ||	1	1.05	0.31	1.60	1.13	1.33	0.56	1.87	1.06
325	|| orf19.7347 ||  ||  || Ortholog(s) have ubiquitin-protein ligase activity, role in ER-associated ubiquitin-dependent protein catabolic process and endoplasmic reticulum membrane localization ||	1	0.60	0.10	0.94	0.72	0.66	0.20	1.10	0.79
326	|| orf19.7179 ||  ||  || Ortholog(s) have role in intracellular sequestering of iron ion, iron-sulfur cluster assembly, protein maturation and mitochondrial matrix localization ||	1	0.35	0.10	0.63	0.61	0.52	0.05	0.74	0.48
327	|| orf19.5962 || HGT4 ||  || Glucose and galactose sensor; fermentation, filamentation, virulence roles; 20-member glucose transporter family; extended C terminus; high-glucose repressed; macrophage induced; flow model biofilm repressed; Spider biofilm induced ||	1	0.61	0.16	0.93	0.62	0.54	0.11	0.93	0.48
328	|| orf19.4166 || ZCF21 ||  || Predicted Zn(II)2Cys6 transcription factor; mutants display increased colonization of mouse kidneys; Spider biofilm induced ||	1	0.82	0.27	1.14	0.94	0.65	0.39	1.06	0.69
329	|| orf19.1630 ||  ||  || Ortholog(s) have cytoplasm localization ||	1	0.54	0.16	0.71	0.64	0.42	0.40	0.72	0.55
330	|| orf19.633 || CRG1 ||  || Methyltransferase involved in sphingolipid homeostasis, methylates a drug cantharidin; decreased expression in hyphae compared to yeast; expression regulated during planktonic growth; flow model biofilm induced; Hap43-repressed gene ||	1	0.79	0.02	1.18	1.22	0.96	0.65	1.51	0.96
331	|| orf19.633 || CRG1 ||  || Methyltransferase involved in sphingolipid homeostasis, methylates a drug cantharidin; decreased expression in hyphae compared to yeast; expression regulated during planktonic growth; flow model biofilm induced; Hap43-repressed gene ||	1	0.79	0.02	1.18	1.22	0.96	0.65	1.51	0.96
332	|| orf19.4503 ||  ||  || Similar to HMG-box variant of S. pombe; Spider biofilm repressed ||	1	0.46	0.12	0.87	0.62	0.59	0.43	1.00	0.35
333	|| orf19.7449 ||  ||  || Ortholog(s) have role in mitochondrial genome maintenance, plasmid maintenance and cytosol, mitochondrion localization ||	1	0.40	0.27	0.82	0.75	0.61	0.32	0.93	0.35
334	|| orf19.6552 ||  ||  || Flavin-linked sulfhydryl oxidase; predicted localization to endoplasmic reticulum lumen; involved in disulfide bond formation within the ER; Spider biofilm induced ||	1	0.44	0.30	0.61	0.62	0.62	0.10	0.71	0.23
335	|| orf19.4170 || CSP2 ||  || Putative cell wall associated protein; C. albicans and C. dubliniensis specific gene highly induced during chlamydospore development in both species; localized to chlamydospore cell wall; Hap43-repressed; Spider biofilm induced ||	1	1.21	0.76	1.50	1.34	1.52	0.43	2.06	0.75
336	|| orf19.7345 ||  ||  || Ortholog(s) have ATP binding activity and cytosol, nucleus localization ||	1	0.73	0.64	1.07	1.00	0.88	0.14	1.35	0.67
337	|| orf19.5275 ||  ||  || Ortholog(s) have ATPase activator activity, role in late endosome to vacuole transport via multivesicular body sorting pathway, positive regulation of protein oligomerization and endosome membrane, multivesicular body localization ||	1	0.52	0.42	1.60	1.17	1.42	0.47	1.26	0.87
338	|| orf19.1444 ||  ||  || Ortholog(s) have phosphatidylinositol-4,5-bisphosphate binding activity, role in actin cortical patch assembly, actin filament organization, endocytosis and actin cortical patch, mating projection tip localization ||	1	1.00	0.79	2.13	0.92	1.51	0.65	1.40	0.52
339	|| orf19.1444 ||  ||  || Ortholog(s) have phosphatidylinositol-4,5-bisphosphate binding activity, role in actin cortical patch assembly, actin filament organization, endocytosis and actin cortical patch, mating projection tip localization ||	1	1.00	0.79	2.13	0.92	1.51	0.65	1.40	0.52
340	|| orf19.4183 || MUC1 ||  || Protein similar to S. cerevisiae Muc1; a cell surface glycoprotein involved in filamentous growth; repressed by benomyl treatment; mutant is viable ||	1	0.63	0.59	1.30	0.62	0.59	0.09	0.80	0.39
341	|| orf19.7537 || BNR1 ||  || Formin; probable role in hyphal cytoskeletal polarity; synthetic lethality if Bnr1p and Bni1p are absent ||	1	0.67	0.61	1.19	0.59	0.41	0.25	0.82	0.48
342	|| orf19.7537 || BNR1 ||  || Formin; probable role in hyphal cytoskeletal polarity; synthetic lethality if Bnr1p and Bni1p are absent ||	1	0.67	0.61	1.19	0.59	0.41	0.25	0.82	0.48
343	|| orf19.5426 ||  ||  || Putative patatin-like phospholipase; macrophage-regulated gene; fungal-specific (no human or murine homolog) ||	1	1.01	0.95	1.57	0.84	0.68	0.24	1.08	0.75
344	|| orf19.1443 || PLB4 ||  || Putative phospholipase B; merged with orf19.1442 in Assembly 20 ||	1	0.65	0.57	1.00	0.42	0.51	0.34	0.63	0.37
345	|| orf19.367 || CNH1 ||  || Na+/H+ antiporter; required for wild-type growth, cell morphology, and virulence in a mouse model of systemic infection; not transcriptionally regulated by NaCl; fungal-specific (no human or murine homolog) ||	1	1.17	0.90	1.51	1.21	0.92	0.42	1.25	0.88
346	|| orf19.1964 ||  ||  || Protein of unknown function; repressed by fluphenazine treatment; induced by benomyl treatment and in an RHE model; regulated by Nrg1, Tup1 ||	1	1.02	0.86	1.30	1.16	0.76	0.66	1.16	0.70
347	|| orf19.4589 ||  ||  || Ortholog(s) have polyamine oxidase activity, role in pantothenate biosynthetic process, polyamine catabolic process and cytoplasm localization ||	1	0.57	0.57	0.83	0.64	0.41	0.34	0.75	0.60
348	|| orf19.4384 || HXT5 ||  || Putative sugar transporter; induced by ciclopirox olamine; Snf3-induced; alkaline repressed; colony morphology-related gene regulation by Ssn6; possibly essential gene ||	1	0.85	1.07	1.39	0.97	0.84	0.55	1.21	0.76
349	|| orf19.5773 ||  ||  || Putative dipeptidyl-peptidase III; protein detected by mass spec in exponential and stationary phase cultures; Hog1p-induced; clade-associated gene expression ||	1	0.47	0.54	0.99	0.59	0.47	0.34	0.67	0.50
350	|| orf19.2887 ||  ||  || Ortholog in S. cerevisiae is localizedto the bud, mating projection tip, and associates with ribosomes; Spider biofilm induced ||	1	0.54	0.39	0.88	0.68	0.33	0.32	0.65	0.57
351	|| orf19.7504 ||  ||  || Ortholog of S. cerevisiae Rts3; a component of the protein phosphatase type 2A complex; Plc1-regulated; induced in core caspofungin response; Spider biofilm induced ||	1	1.16	0.50	1.99	1.27	1.25	0.84	1.36	0.87
352	|| orf19.7374 || CTA4 ||  || Zn(II)2Cys6 transcription factor; induced by nitric oxide; induced by Mnl1 under weak acid stress; repressed upon adherence to polystyrene; Hap43-repressed; Spider biofilm induced ||	1	0.48	0.40	1.02	0.68	0.78	0.50	0.90	0.36
353	|| orf19.2204.2 || RHO2 ||  || Ortholog(s) have GTPase activity ||	1	0.61	0.58	1.06	0.85	0.75	0.51	0.87	0.48
354	|| orf19.2607 ||  ||  || Protein of unknown function; Spider biofilm induced ||	1	0.73	0.60	1.11	0.76	0.98	0.40	0.85	0.56
355	|| orf19.3627 ||  ||  || Ortholog of <i>C. dubliniensis CD36</i> : Cd36_22640, <i>C. parapsilosis CDC317</i> : CPAR2_406910, <i>Candida tenuis NRRL Y-1498</i> : CANTEDRAFT_104937 and <i>Debaryomyces hansenii CBS767</i> : DEHA2D02706g ||	1	1.99	0.91	2.81	2.01	2.12	0.91	2.35	0.93
356	|| orf19.4657 ||  ||  || Ortholog(s) have phosphoprotein phosphatase activity, role in negative regulation of phospholipid biosynthetic process, nuclear envelope organization and Nem1-Spo7 phosphatase complex, integral to membrane, mitochondrion localization ||	1	1.07	0.60	1.50	1.01	1.10	0.51	1.30	0.71
357	|| orf19.641 ||  ||  || Ortholog(s) have role in protein folding and endoplasmic reticulum localization ||	1	0.86	0.54	1.12	0.70	0.74	0.36	1.03	0.42
358	|| orf19.641 ||  ||  || Ortholog(s) have role in protein folding and endoplasmic reticulum localization ||	1	0.86	0.54	1.12	0.70	0.74	0.36	1.03	0.42
359	|| orf19.6558 ||  ||  || Has domain(s) with predicted zinc ion binding activity, role in ER to Golgi vesicle-mediated transport, intracellular protein transport and COPII vesicle coat localization ||	1	0.78	0.48	0.80	0.72	0.75	0.54	0.86	0.55
360	|| orf19.6558 ||  ||  || Has domain(s) with predicted zinc ion binding activity, role in ER to Golgi vesicle-mediated transport, intracellular protein transport and COPII vesicle coat localization ||	1	0.78	0.48	0.80	0.72	0.75	0.54	0.86	0.55
361	|| orf19.286 ||  ||  || Has a predicted autophagy-related protein domain; transcription repressed by fluphenazine treatment ||	1	1.05	1.30	1.18	1.12	0.96	0.95	1.79	0.95
362	|| orf19.541 ||  ||  || Has domain(s) with predicted oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors activity ||	1	0.69	0.65	0.76	0.93	0.71	0.26	1.15	0.79
363	|| orf19.6348 ||  ||  || Predicted cysteine proteinase domain; mutants are viable ||	1	0.74	0.97	0.97	1.15	0.57	0.22	1.28	0.56
364	|| orf19.5345 ||  ||  || Putative ubiquitin-like polyubiquitin-binding protein; induced by nitric oxide independent of Yhb1; Spider biofilm repressed ||	1	0.38	0.53	0.65	0.71	0.29	0.31	0.64	0.42
365	|| orf19.6169.2 ||  ||  || ORF Predicted by Annotation Working Group; fluconazole-downregulated; merged with orf19.2496 in Assembly 20 ||	1	0.78	0.87	1.39	1.35	0.83	0.72	0.97	0.55
366	|| orf19.5094 || BUL1 ||  || Protein similar but not orthologous to S. cerevisiae Bul1; a protein involved in selection of substrates for ubiquitination; mutants are viable; macrophage/pseudohyphal-induced; rat catheter biofilm induced ||	1	0.94	0.95	2.05	1.62	1.31	0.84	1.04	0.92
367	|| orf19.3661 ||  ||  || Putative deubiquitinating enzyme; induced by Mnl1 under weak acid stress ||	1	0.38	0.49	0.75	0.76	0.64	0.11	0.53	0.48
368	|| orf19.517 || HAP31 ||  || CCAAT-binding transcription factor; regulates CYC1; required for resistance to rapamycin, copper; induced in high iron; repressed in low iron; Sef1, Sfu1, and Hap43 regulated; rat catheter and Spider biofilm induced ||	1	0.54	0.80	1.21	1.23	0.85	0.44	0.97	0.90
369	|| orf19.6867 ||  ||  || Protein with a predicted cytochrome b5-like heme/steroid binding domain; repressed by alpha pheromone in SpiderM medium ||	1	0.28	0.57	0.77	0.80	0.60	0.24	0.63	0.47
370	|| orf19.945 || VPS2 ||  || Ortholog(s) have role in intralumenal vesicle formation, protein retention in Golgi apparatus, protein targeting to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway ||	1	0.39	0.76	1.08	0.90	0.70	0.37	0.82	0.52
371	|| orf19.6187 ||  ||  || possible pseudouridine monophosphate glycosidase; overlaps orf19.6185 and orf19.618; has intron; Spider biofilm repressed ||	1	0.35	0.69	0.79	0.68	0.46	0.21	0.49	0.42
372	|| orf19.6900 ||  ||  || Ortholog(s) have role in establishment or maintenance of cell polarity, mitochondrial genome maintenance, mitochondrion inheritance, phospholipid transport, protein import into mitochondrial outer membrane ||	1	0.30	0.57	0.81	0.74	0.46	0.10	0.51	0.39
373	|| orf19.4070 ||  ||  || Ortholog of <i>C. dubliniensis CD36</i> : Cd36_23270 ||	1	0.27	0.64	0.76	0.63	0.41	0.24	0.56	0.75
374	|| orf19.5799 ||  ||  || Ortholog(s) have cytoplasm localization ||	1	0.73	1.02	1.78	1.27	0.61	0.61	1.26	1.37
375	|| orf19.5799 ||  ||  || Ortholog(s) have cytoplasm localization ||	1	0.73	1.02	1.78	1.27	0.61	0.61	1.26	1.37
376	|| orf19.1917 ||  ||  || Protein of unknown function; Spider biofilm repressed ||	1	0.37	0.54	0.89	0.61	0.31	0.29	0.53	0.58
377	|| orf19.273 ||  ||  || Ortholog(s) have unfolded protein binding activity, role in sterol biosynthetic process and endoplasmic reticulum localization ||	1	0.24	0.32	0.82	0.62	0.31	0.35	0.47	0.43
378	|| orf19.6883 ||  ||  || Putative oxysterol binding protein family; probable peripheral membrane protein of the Golgi complex; flow model and Spider biofilm repressed ||	1	0.15	0.39	0.80	0.68	0.38	0.40	0.51	0.60
379	|| orf19.6043 ||  ||  || Ortholog(s) have mitochondrial membrane localization ||	1	0.37	0.56	1.30	0.92	0.81	0.35	0.77	0.84
380	|| orf19.4593 || RGA2 ||  || Putative GTPase-activating protein (GAP) for Rho-type GTPase Cdc42; involved in cell signaling pathways controlling cell polarity; induced by low-level peroxide stress; flow model biofilm induced ||	1	0.22	0.26	0.70	0.65	0.49	0.20	0.43	0.45
381	|| orf19.4191.1 ||  ||  || Ortholog(s) have ubiquitin-ubiquitin ligase activity, role in ER-associated ubiquitin-dependent protein catabolic process, protein polyubiquitination and cytosol, nuclear envelope, proteasome complex localization ||	1	0.57	0.63	1.70	1.52	0.95	0.47	1.80	1.62
382	|| orf19.3811 || GYP1 ||  || Putative Cis-golgi GTPase-activating protein; transcript regulated by Nrg1, Mig1, and Tup1 ||	1	0.72	0.68	1.89	1.79	0.88	0.63	1.89	1.78
383	|| orf19.5248 || MSO1 ||  || Putative secretory protein involved in S. cerevisiae sporulation; repressed during pseudohyphal growth in the presence of lysed macrophages; Hap43-repressed; Spider biofilm induced ||	1	0.37	0.44	1.46	1.56	0.65	0.57	1.54	1.13
384	|| orf19.589 || VPS21 ||  || Late endosomal Rab small monomeric GTPase involved in transport of endocytosed proteins to the vacuole; involved in filamentous growth and virulence; Spider biofilm induced ||	1	0.32	0.42	1.00	0.72	0.41	0.23	0.72	0.49
385	|| orf19.5777 ||  ||  || Protein of unknown function; F-12/CO2 early biofilm induced ||	1	0.77	1.23	2.26	1.91	0.92	0.55	1.62	1.31
386	|| orf19.6674 || BTS1 ||  || Putative geranylgeranyl diphosphate synthase; repressed by benomyl treatment; Spider biofilm induced ||	1	0.97	1.35	2.77	2.69	1.38	0.99	2.33	2.05
387	|| orf19.6411 ||  ||  || Protein similar to S. cerevisiae Vac14p; a protein involved in regulated synthesis of PtdIns(3,5)P(2); transposon mutation affects filamentous growth ||	1	0.41	0.49	1.24	1.18	0.43	0.43	0.93	0.87
388	|| orf19.6102 || RCA1 ||  || Protein involved in regulation of carbonic anhydrases; controls CO2 sensing; bZIP domain-containing transcription factor of the ATF/CREB family; null mutant displays slow growth, abnormal colony morphology and invasive growth ||	1	0.29	0.51	0.95	0.82	0.33	0.35	0.71	0.87
389	|| orf19.3058 || COQ6 ||  || Ortholog(s) have role in ubiquinone biosynthetic process and mitochondrial inner membrane localization ||	1	0.33	0.53	0.95	0.99	0.32	0.41	0.78	0.91
390	|| orf19.6860 ||  ||  || Ortholog(s) have CDP-diacylglycerol-inositol 3-phosphatidyltransferase activity, role in phosphatidylinositol biosynthetic process and Golgi apparatus, integral to membrane, mitochondrial outer membrane localization ||	1	0.24	0.47	0.71	0.86	0.23	0.42	0.70	0.66
391	|| orf19.489 || DAP1 ||  || Similar to mammalian membrane-associated progesterone receptors involved in DNA damage response; induced in core stress response; Hog1 regulated; clade-associated expression; Hap43-repressed ||	1	0.37	1.02	1.60	1.97	0.81	0.97	1.42	1.47
392	|| orf19.6626 ||  ||  || Predicted homeodomain-containing protein; possible transcription factor; possibly transcriptionally regulated upon hyphal formation ||	1	0.21	0.40	0.90	1.14	0.44	0.50	0.93	0.86
393	|| orf19.3659 ||  ||  || Putative CTD phosphatase; role in dephosphorylation of RNA polymerase II C-terminal domain, transcription from RNA polymerase II promoter; flow model biofilm induced ||	1	0.16	0.32	0.69	0.80	0.38	0.31	0.67	0.69
394	|| orf19.4127 ||  ||  || Ortholog(s) have actin filament binding activity, role in actin cortical patch localization, actin filament bundle assembly, endocytosis and actin cortical patch localization ||	1	0.19	0.24	0.60	0.78	0.34	0.23	0.61	0.57
395	|| orf19.3008 || COQ4 ||  || Protein with a putative role in coenzyme Q biosynthesis; transcriptionally induced by interaction with macrophage; Hap43p-repressed gene ||	1	0.57	0.59	1.22	1.46	0.94	0.64	1.35	1.32
396	|| orf19.6057 ||  ||  || Ortholog(s) have 3-methyl-2-oxobutanoate hydroxymethyltransferase activity, role in pantothenate biosynthetic process, respiratory chain complex IV assembly and mitochondrion localization ||	1	0.48	0.41	0.91	1.17	0.55	0.51	0.97	0.93
397	|| orf19.2350 ||  ||  || Protein similar to S. cerevisiae Yor378w; MFS family transporter; transposon mutation affects filamentous growth; null mutants are viable; fungal-specific (no human or murine homolog) ||	1	0.73	0.80	1.75	2.13	1.00	0.94	1.67	1.61
398	|| orf19.3737 ||  ||  || Protein with a Vps9 vacuolar protein sorting protein domain; Hap43-repressed; repressed by ciclopirox olamine; Spider biofilm induced ||	1	0.67	0.94	1.53	1.75	0.99	0.81	1.61	1.40
399	|| orf19.1881 ||  ||  || Putative broad-specificity lysophospholipid acyltransferase; role in glycerophospholipid biosynthesis; rat catheter biofilm repressed ||	1	0.56	0.65	1.29	1.15	0.54	0.57	1.24	1.05
400	|| orf19.1881 ||  ||  || Putative broad-specificity lysophospholipid acyltransferase; role in glycerophospholipid biosynthesis; rat catheter biofilm repressed ||	1	0.56	0.65	1.29	1.15	0.54	0.57	1.24	1.05
401	|| orf19.4802 || FTH1 ||  || Protein similar to S. cerevisiae Fth1p, a high affinity iron transporter for intravacuolar stores of iron; repressed by Sfu1p, amphotericin B, caspofungin; induced by alkaline pH, ciclopirox olamine; regulated by Sef1p, Sfu1p, and Hap43p ||	1	1.37	1.37	2.41	2.37	1.23	0.91	2.72	2.39
402	|| orf19.4031 ||  ||  || Ortholog(s) have cytoplasm localization ||	1	0.83	0.84	1.32	1.33	0.70	0.54	1.52	1.30
403	|| orf19.4014 ||  ||  || Planktonic growth-induced gene ||	1	0.62	1.07	1.19	1.26	0.78	0.67	1.38	1.36
404	|| orf19.5210 ||  ||  || Putative Xbp1 transcriptional repressor; binds to cyclin gene promoters in S. cerevisiae; Hap43-repressed; possibly essential, disruptants not obtained by UAU1 method ||	1	0.59	1.09	1.43	1.45	0.84	0.55	1.55	1.21
405	|| orf19.7329 ||  ||  || Ortholog(s) have ubiquitin-protein ligase activity ||	1	0.69	1.05	1.61	1.61	0.79	0.83	1.30	1.20
406	|| orf19.7456 ||  ||  || Protein of unknown function; flow model biofilm repressed ||	1	0.74	1.36	2.12	2.04	1.12	1.09	1.96	1.83
407	|| orf19.1162 ||  ||  || Protein of unknown function; transcript upregulated by benomyl treatment ||	1	0.26	0.59	0.80	0.72	0.41	0.44	0.68	0.75
408	|| orf19.6953 || IRS4 ||  || Protein with roles in cell wall integrity, systemic (but not oral) murine infection, adherence, hyphal growth, and agar-embedded filamentous growth; antigenic in human infection; similar to S. cerevisiae Irs4p ||	1	0.37	0.48	0.96	0.68	0.57	0.38	0.73	0.60
409	|| orf19.1570 || ERG7 ||  || 2,3-epoxysqualene-lanosterol cyclase (lanosterol synthase), conversion of 2,3-oxidosqualene to lanosterol in sterol biosynthesis; fluconazole-induced; possibly essential, disruptants not obtained by UAU1 method; rat catheter biofilm induced ||	1	0.62	0.66	1.47	1.08	0.87	0.68	1.43	1.24
410	|| orf19.2948 || SNO1 ||  || Protein with a predicted role in pyridoxine metabolism; stationary phase protein; regulated by Tup1, Efg1; Spider biofilm induced ||	1	0.48	0.53	1.25	0.98	0.84	0.57	1.21	0.93
411	|| orf19.7043 ||  ||  || Ortholog(s) have endoplasmic reticulum localization ||	1	1.32	0.91	2.37	1.85	1.46	1.22	2.30	1.59
412	|| orf19.1800 ||  ||  || Protein of unknown function; Spider biofilm induced ||	1	1.17	1.14	2.21	1.96	1.34	1.11	2.18	1.77
413	|| orf19.496 ||  ||  || Ortholog(s) have DNA-dependent ATPase activity, dinucleotide insertion or deletion binding, guanine/thymine mispair binding activity, role in mismatch repair, mitochondrial DNA repair and mitochondrion localization ||	1	1.24	1.19	2.15	1.93	1.35	1.00	1.86	1.61
414	|| orf19.1801 || CBR1 ||  || Putative cytochrome B5 reductase; plasma membrane-localized ||	1	0.76	0.65	1.26	1.03	0.90	0.63	1.00	0.86
415	|| orf19.4747 || HEM14 ||  || Putative protoporphyrinogen oxidase; involved in heme biosynthesis; predicted Kex2p substrate; iron regulated transcript; Yfh1-induced; Hap43-repressed; rat catheter biofilm repressed ||	1	1.05	0.69	1.85	1.56	1.15	0.88	1.52	1.17
416	|| orf19.288 || MET13 ||  || Putative methionine biosynthesis protein; ketoconazole-induced; amphotericin B repressed; Spider biofilm repressed ||	1	0.82	0.62	1.56	1.31	1.08	0.57	1.32	0.99
417	|| orf19.5812 ||  ||  || Ortholog of S. cerevisiae Ett1, a nuclear protein that inhibits replication of Brome mosaic virus; early-stage flow model biofilm induced ||	1	0.29	0.20	0.64	0.61	0.40	0.32	0.56	0.44
418	|| orf19.3536 ||  ||  || Ortholog(s) have acetylglucosaminyltransferase activity, role in protein N-linked glycosylation and Golgi medial cisterna localization ||	1	0.46	0.28	0.74	0.74	0.44	0.28	0.71	0.49
419	|| orf19.3991 ||  ||  || Ortholog(s) have role in cellular lipid metabolic process and cytosol localization ||	1	0.43	0.22	0.74	0.71	0.39	0.32	0.76	0.62
420	|| orf19.3008 || COQ4 ||  || Protein with a putative role in coenzyme Q biosynthesis; transcriptionally induced by interaction with macrophage; Hap43p-repressed gene ||	1	0.78	0.53	1.39	1.51	0.88	0.63	1.55	1.23
421	|| orf19.7547 ||  ||  || Ortholog(s) have phosphatidylinositol-3-phosphate binding, ubiquitin-protein ligase activity, role in protein ubiquitination and cytosol, fungal-type vacuole membrane, late endosome, nucleus localization ||	1	0.88	0.63	1.50	1.41	1.01	0.63	1.65	1.23
422	|| orf19.2423 || ZCF11 ||  || Zn(II)2Cys6 transcription factor; required for wild-type filamentous growth; mRNA binds She3 ||	1	0.74	0.60	1.46	1.34	1.05	0.52	1.53	1.20
423	|| orf19.3705 || PTC6 ||  || Mitochondrial protein phosphatase of the Type 2C-related family (serine/threonine-specific), functional homolog of <i>S. cerevisiae</i> Ptc6p; mutant shows virulence defect ||	1	0.75	0.43	1.07	1.10	0.74	0.28	1.20	0.94
424	|| orf19.1985 ||  ||  || Has aminoglycoside phosphotransferase and protein kinase domains; rat catheter and flow model biofilm induced ||	1	0.70	0.47	1.27	1.09	0.72	0.35	1.22	1.14
425	|| orf19.6942 || ORC3 ||  || Protein similar to S. cerevisiae Orc3p, which is a component of the origin recognition complex involved in DNA replication; mutation confers hypersensitivity to toxic ergosterol analog; induced under hydroxyurea treatment ||	1	0.50	0.23	0.88	0.69	0.54	0.24	0.87	0.65
426	|| orf19.2622 || YPT31 ||  || Protein required for resistance to toxic ergosterol analog ||	1	0.57	0.31	0.99	0.72	0.79	0.48	0.94	0.63
427	|| orf19.3733 || IDP2 ||  || Isocitrate dehydrogenase; white-opaque switch regulated; morphology-regulation by Ssn6; protein in exponential and stationary phase yeast; Hap43-repressed; Spider biofilm repressed by Bcr1, Tec1, Ndt80, Rob1, Brg1; Spider biofilm induced ||	1	1.15	0.65	1.72	1.47	1.40	0.99	1.67	1.32
428	|| orf19.3616 || ERG9 ||  || Putative farnesyl-diphosphate farnesyl transferase (squalene synthase); sterol biosynthesis pathway; likely essential for growth; regulated by fluconazole, lovastatin; amphotericin B, caspofungin repressed; Spider biofilm repressed ||	1	0.62	0.36	0.99	0.78	0.73	0.60	0.87	0.83
429	|| orf19.2286 ||  ||  || Putative deoxyhypusine hydroxylase; ketoconazole-induced; protein level decreases in stationary phase cultures; required for biofilm formation; Spider biofilm repressed ||	1	0.44	0.21	0.68	0.49	0.60	0.43	0.68	0.61
430	|| orf19.2952 || EXG2 ||  || GPI-anchored cell wall protein, similar to S. cerevisiae exo-1,3-beta-glucosidase Exg2p; predicted Kex2p substrate; induced during cell wall regeneration; possibly an essential gene, disruptants not obtained by UAU1 method; Hap43p-repressed ||	1	0.98	0.48	1.26	1.24	1.01	0.54	1.28	0.92
431	|| orf19.4102 || RPN10 ||  || Putative 19S regulatory particle of the 26S proteasome; macrophage/pseudohyphal-repressed; regulated by Gcn2 and Gcn4; Spider biofilm repressed ||	1	0.40	0.24	0.60	0.64	0.54	0.25	0.54	0.40
432	|| orf19.2257 ||  ||  || Predicted ER protein involved in ER-nucleus signaling; Spider biofilm repressed ||	1	0.25	0.35	0.56	0.68	0.38	0.30	0.45	0.33
433	|| orf19.6840 ||  ||  || Protein of unknown function; transcript detected in high-resolution tiling arrays; transcription induced by alpha pheromone in SpiderM medium; Spider and early-stage flow model biofilm induced ||	1	0.96	1.07	2.03	2.12	1.36	1.26	1.65	1.39
434	|| orf19.3483 ||  ||  || Putative phosphatidyl glycerol phospholipase C; Plc1-regulated; flow model biofilm induced; Spider biofilm induced ||	1	1.03	1.29	2.40	2.23	1.55	1.14	1.81	1.73
435	|| orf19.2278 ||  ||  || Putative 20S proteasome assembly protein; filament induced; induced by alpha pheromone in SpiderM medium ||	1	0.50	0.67	1.34	1.13	0.70	0.49	0.88	0.79
436	|| orf19.7263 ||  ||  || Putative X-Pro aminopeptidase; Spider biofilm repressed ||	1	0.86	0.92	1.55	1.48	0.67	0.74	1.07	0.93
437	|| orf19.7504 ||  ||  || Ortholog of S. cerevisiae Rts3; a component of the protein phosphatase type 2A complex; Plc1-regulated; induced in core caspofungin response; Spider biofilm induced ||	1	1.06	0.87	1.59	1.70	0.94	1.02	1.16	1.05
438	|| orf19.344 ||  ||  || Protein of unknown function; upregulated by fluphenazine treatment or in an azole-resistant strain that overexpresses CDR1 and CDR2; transcript possibly regulated by Tac1 ||	1	3.03	3.17	4.64	4.37	3.28	2.88	3.73	3.35
439	|| orf19.5604 || MDR1 ||  || Plasma membrane MDR/MFS multidrug efflux pump; methotrexate is preferred substrate; overexpression in drug-resistant clinical isolates confers fluconazole resistance; repressed in young biofilms; rat catheter biofilm induced ||	1	2.57	2.46	3.91	3.00	2.73	2.61	2.55	2.51
440	|| orf19.2672 || NCP1 ||  || NADPH-cytochrome P450 reductase, acts with Erg11p in sterol 14 alpha-demethylation in ergosterol biosynthesis; subject to hypoxic regulation; ketoconazole-induced; caspofungin repressed ||	1	0.66	0.76	1.38	0.98	0.79	0.91	0.94	0.92
441	|| orf19.5591 || ADO1 ||  || Adenosine kinase; heterozygous null mutant is resistant to cordycepin in C. albicans fitness test; ketoconazole-induced; protein level decrease in stationary phase cultures; sumoylation target; Spider biofilm repressed ||	1	0.43	0.36	0.63	0.69	0.45	0.59	0.58	0.51
442	|| orf19.2451 || PGA45 ||  || Putative GPI-anchored cell wall protein; repressed in core caspofungin response; Hog1-induced; regulated by Ssn6; Mob2-dependent hyphal regulation; flow model biofilm induced ||	1	0.80	0.61	1.08	1.15	0.80	0.95	0.98	1.22
443	|| orf19.1598 || ERG24 ||  || C-14 sterol reductase, has a role in ergosterol biosynthesis; mutation confers increased sensitivity to dyclonine; rat catheter and Spider biofilm repressed ||	1	0.77	0.76	1.23	1.10	0.73	0.87	1.06	1.17
444	|| orf19.3240 || ERG27 ||  || 3-Keto sterol reductase of ergosterol biosynthesis; acts in C-4 sterol demethylation with Erg25p and Erg26p; possible drug target, essential for viability; functional homolog of S. cerevisiae Erg27p ||	1	0.82	1.04	1.74	1.78	1.14	1.11	1.65	1.67
445	|| orf19.5634 || FRP1 ||  || Ferric reductase; alkaline-induced by Rim101; iron-chelation-induced by CCAAT-binding factor; fluconazole-repressed; ciclopirox-, hypoxia-, Hap43-induced; colony morphology-related regulation by Ssn6; Spider and flow model biofilm induced ||	1	2.42	2.51	4.11	4.13	3.01	2.56	4.03	3.88
446	|| orf19.2909 || ERG26 ||  || C-3 sterol dehydrogenase, catalyzes the 2nd of 3 steps required to remove 2 C-4 methyl groups from an intermediate in ergosterol biosynthesis; amphotericin B, caspofungin repressed; Spider biofilm repressed ||	1	0.80	0.72	1.45	1.37	1.12	1.00	1.46	1.43
447	|| orf19.2652 || TEF4 ||  || Putative translation elongation factor; genes encoding ribosomal subunits, translation factors, and tRNA synthetases are downregulated upon phagocytosis by murine macrophage ||	1	4.04	4.05	5.80	6.50	4.90	5.03	6.03	6.08
448	|| orf19.260 || SLD1 ||  || Sphingolipid delta-8 desaturase; catalyzes desaturation at C8 in the long-chain base moiety of ceramides in glucosylceramide synthesis, important for virulence; ketoconazole and hypoxia induced; Hap43-repressed; Spider biofilm induced ||	1	0.71	0.53	0.90	1.02	0.79	0.67	0.93	0.83
449	|| orf19.7221 || SET3 ||  || NAD-dependent histone deacetylase; mutations affect filamentous growth; genetic evidence suggests Set3/Hos2 function as a complex to regulate white-opaque switching, morphogenesis, and virulence; flow model biofilm induced ||	1	1.49	1.42	2.66	2.51	2.14	1.87	2.27	2.27
450	|| orf19.406 || ERG1 ||  || Squalene epoxidase, epoxidation of squalene to 2,3(S)-oxidosqualene; ergosterol biosynthesis; allylamine antifungal drug target; NADH reducing cofactor but S. cerevisiae Erg1 uses NADPH; flow model biofilm induced; Spider biofilm repressed ||	1	0.86	0.81	1.42	1.18	1.11	0.98	1.22	1.21
451	|| orf19.6026 || ERG2 ||  || C-8 sterol isomerase; enzyme of ergosterol biosynthesis; converts fecosterol to episterol; mutant is hypersensitive to multiple drugs; ketoconazole-induced; flow model and Spider biofilm repressed ||	1	0.78	0.56	1.18	0.92	0.92	0.91	1.06	0.97
452	|| orf19.922 || ERG11 ||  || Lanosterol 14-alpha-demethylase; cytochrome P450 family; role in ergosterol biosynthesis; target of azole antifungals; may contribute to drug resistance; azole or flow model biofilm induced; drug treated biofilm induced; hypoxia regulated ||	1	0.65	0.51	0.85	0.69	0.74	0.66	0.74	0.74
453	|| orf19.260 || SLD1 ||  || Sphingolipid delta-8 desaturase; catalyzes desaturation at C8 in the long-chain base moiety of ceramides in glucosylceramide synthesis, important for virulence; ketoconazole and hypoxia induced; Hap43-repressed; Spider biofilm induced ||	1	0.81	0.58	1.14	0.88	0.80	0.67	1.03	0.91
454	|| orf19.1865 || MCS7 ||  || S. cerevisiae ortholog Mcs7 has a role in reciprocal meiotic recombination; Spider biofilm repressed ||	1	1.25	1.16	1.87	1.56	1.26	1.13	1.78	1.64
455	|| orf19.4013 ||  ||  || Putative protein of unknown function; Hap43p-repressed gene; <I>S. cerevisiae</I> ortholog YHR045W localizes to the endoplasmic reticulum ||	1	1.38	1.14	2.06	1.83	1.63	1.48	2.26	1.92
456	|| orf19.6025 ||  ||  || Ortholog(s) have N-acetylglucosaminyldiphosphodolichol N-acetylglucosaminyltransferase activity and role in dolichol-linked oligosaccharide biosynthetic process ||	1	1.12	1.10	1.97	2.37	1.92	1.65	2.38	2.39
457	|| orf19.417 || MTM1 ||  || Ortholog(s) have metallochaperone activity, role in manganese ion transport and mitochondrion localization ||	1	0.46	0.51	0.70	0.85	0.37	0.62	0.65	0.67
458	|| orf19.5635 || PGA7 ||  || GPI-linked hyphal surface antigen; induced by ciclopirox olamine, ketoconazole, Rim101 at pH 8; Hap43, fluconazole; flow model biofilm induced; Spider biofilm induced; required for RPMI biofilm; Bcr1-induced in a/a biofilm ||	1	1.19	1.87	2.51	2.88	1.45	1.92	2.25	2.62
459	|| orf19.4082 || DDR48 ||  || Immunogenic stress-associated protein; filamentation regulated; induced by benomyl/caspofungin/ketoconazole or in azole-resistant strain; Hog1, farnesol, alkaline repressed; stationary phase enriched; Spider, flow model biofilm induced ||	1	1.15	2.11	2.52	2.22	1.42	1.51	1.75	2.10
460	|| orf19.329 ||  ||  || Putative pre-mRNA branch point binding protein; role in mRNA splicing via spliceosome; Spider biofilm repressed ||	1	1.05	1.23	1.29	1.37	0.97	0.72	1.32	1.30
461	|| orf19.278 ||  ||  || Protein of unknown function; required for adhesion to abiotic substrate; Spider biofilm induced ||	1	0.48	0.67	0.69	0.89	0.45	0.27	0.57	0.78
462	|| orf19.692 ||  ||  || Protein of unknown function; Hap43-repressed gene; rat catheter and Spider biofilm induced ||	1	0.40	1.43	1.14	1.76	0.76	0.84	1.61	2.03
463	|| orf19.3261 || ATO9 ||  || Putative fungal-specific transmembrane protein ||	1	0.87	1.16	1.42	1.77	0.67	1.20	2.18	2.18
464	|| orf19.5535 ||  ||  || Predicted membrane transporter, member of the anion:cation symporter (ACS) family, major facilitator superfamily (MFS) ||	1	0.49	0.73	1.11	1.38	0.52	0.89	1.32	1.56
465	|| orf19.5535 ||  ||  || Predicted membrane transporter, member of the anion:cation symporter (ACS) family, major facilitator superfamily (MFS) ||	1	0.56	0.71	1.16	1.44	0.62	0.94	1.43	1.69
466	|| orf19.4865 ||  ||  || Ortholog(s) have phosphatidylinositol-3,5-bisphosphate 5-phosphatase activity, phosphatidylinositol-3-phosphatase activity, phosphatidylinositol-4-phosphate phosphatase activity and role in phosphatidylinositol dephosphorylation ||	1	0.25	0.30	0.57	0.65	0.26	0.33	0.67	0.75
467	|| orf19.1570 || ERG7 ||  || 2,3-epoxysqualene-lanosterol cyclase (lanosterol synthase), conversion of 2,3-oxidosqualene to lanosterol in sterol biosynthesis; fluconazole-induced; possibly essential, disruptants not obtained by UAU1 method; rat catheter biofilm induced ||	1	0.50	0.66	1.28	1.06	0.72	0.79	1.28	1.43
468	|| orf19.314 ||  ||  || Ortholog of <i>S. cerevisiae</i> : STB6, <i>C. dubliniensis CD36</i> : Cd36_83110, <i>C. parapsilosis CDC317</i> : CPAR2_103210, <i>Candida tenuis NRRL Y-1498</i> : CANTEDRAFT_133418 and <i>Debaryomyces hansenii CBS767</i> : DEHA2G08382g ||	1	0.17	0.25	0.63	0.52	0.45	0.37	0.68	0.71
469	|| orf19.6753 ||  ||  || Protein with a predicted RING-type zinc finger; possibly an essential gene, disruptants not obtained by UAU1 method ||	1	0.53	0.58	1.74	0.63	0.88	0.59	1.56	1.01
470	|| orf19.5711 ||  ||  || Putative phosphatidylinositol transfer protein; possibly an essential gene, disruptants not obtained by UAU1 method ||	1	0.48	0.44	1.09	0.54	0.47	0.30	0.87	0.77
471	|| orf19.1881 ||  ||  || Putative broad-specificity lysophospholipid acyltransferase; role in glycerophospholipid biosynthesis; rat catheter biofilm repressed ||	1	0.50	0.23	1.15	0.46	0.34	0.43	1.06	0.88
472	|| orf19.4411 || HOS1 ||  || Histone deacetylase; similar to S. cerevisiae Hos1; has conserved deacetylation motif; slightly greater expression in white cells than in opaque cells ||	1	0.16	-0.11	0.56	0.51	0.34	0.26	0.75	0.57
473	|| orf19.7459 ||  ||  || Putative mitochondrial protein with a predicted role in respiratory growth; fluconazole-induced; ketoconazole-repressed; mutants display a strong defect in flow model biofilm formation; Spider biofilm induced ||	1	0.23	-0.16	0.61	0.60	0.34	0.30	0.67	0.72
474	|| orf19.1306 ||  ||  || Ortholog(s) have cytosol, nucleus localization ||	1	0.22	-0.15	1.10	1.07	0.49	0.34	0.91	0.86
475	|| orf19.837.1 || INO4 ||  || Transcription factor; activator that forms a heterodimer with Ino2; likely regulates genes involved in phosphatidylcholine and phosphatidylinositol biosynthesis, fatty acid beta-oxidation, and peroxisome biogenesis; gene has intron ||	1	0.18	0.03	0.66	0.76	0.45	0.08	0.73	0.26
476	|| orf19.1730 ||  ||  || HMG-box protein; Spider biofilm repressed ||	1	0.13	0.00	0.71	0.73	0.55	0.05	0.51	0.35
477	|| orf19.5568 || VPS51 ||  || Protein with a role in vacuolar function; null mutant has defect in damaging oral epithelial and vascular endothelial cells; required for normal hyphal growth and stress resistance; induced in presence of host oral or vascular cells ||	1	0.20	0.37	0.99	0.74	0.91	-0.02	0.98	0.59
478	|| orf19.5253 ||  ||  || Has domain(s) with predicted ATP binding, protein tyrosine kinase activity and role in protein phosphorylation ||	1	0.17	0.08	0.71	0.56	0.60	-0.01	0.93	0.44
479	|| orf19.5236.1 ||  ||  || ORF Predicted by Annotation Working Group; merged with orf19.5236 in Assembly 21 ||	1	0.23	0.02	0.54	0.58	0.61	-0.05	0.79	0.36
480	|| orf19.2974 || YKT6 ||  || Putative protein of the vacuolar SNARE complex; predicted role in vacuolar fusion; rat catheter biofilm repressed ||	1	0.24	0.18	0.55	0.58	0.65	0.15	0.75	0.35
481	|| orf19.517 || HAP31 ||  || CCAAT-binding transcription factor; regulates CYC1; required for resistance to rapamycin, copper; induced in high iron; repressed in low iron; Sef1, Sfu1, and Hap43 regulated; rat catheter and Spider biofilm induced ||	1	0.37	0.02	0.42	0.84	0.57	0.20	0.79	0.56
482	|| orf19.2324 || UBA4 ||  || Putative ubiquitin activating protein; Hap43-repressed; induced by prostaglandins; clade-associated gene expression ||	1	0.59	0.01	0.62	0.79	0.70	0.19	0.96	0.67
483	|| orf19.3815 ||  ||  || Has domain(s) with predicted ubiquitin thiolesterase activity and role in ubiquitin-dependent protein catabolic process ||	1	0.51	0.14	0.59	0.82	0.51	-0.05	0.74	0.65
484	|| orf19.2026 || UBP13 ||  || Ortholog of S. cerevisiae Ubp13; putative ubiquitin carboxyl-terminal hydrolase; flow model biofilm induced; rat catheter biofilm repressed ||	1	0.25	0.11	0.74	0.75	0.54	-0.04	1.06	0.68
485	|| orf19.89 || PEX7 ||  || Ortholog(s) have peroxisome matrix targeting signal-2 binding activity, role in fatty acid metabolic process, protein import into peroxisome matrix, docking and cytosol, nucleus, peroxisome localization ||	1	0.22	0.07	0.71	0.90	0.43	0.06	1.08	0.72
486	|| orf19.1314 ||  ||  || Protein of unknown function; planktonic growth-induced gene ||	1	0.36	-0.13	0.72	0.79	0.43	0.02	1.03	0.51
487	|| orf19.91 ||  ||  || Protein of unknown function; flow model biofilm induced; Hap43-repressed ||	1	0.30	-0.11	0.56	0.54	0.32	0.02	0.59	0.36
488	|| orf19.7459 ||  ||  || Putative mitochondrial protein with a predicted role in respiratory growth; fluconazole-induced; ketoconazole-repressed; mutants display a strong defect in flow model biofilm formation; Spider biofilm induced ||	1	0.32	-0.10	0.53	0.40	0.45	0.19	0.69	0.54
489	|| orf19.5925 ||  ||  || Ortholog of <i>S. cerevisiae</i> : AIM6, <i>C. glabrata CBS138</i> : CAGL0C05533g, <i>C. dubliniensis CD36</i> : Cd36_84610, <i>C. parapsilosis CDC317</i> : CPAR2_404550 and <i>Candida tenuis NRRL Y-1498</i> : CANTEDRAFT_115337 ||	1	0.34	0.13	0.54	0.67	0.80	-0.07	0.84	0.82
490	|| orf19.5237 || VPH2 ||  || Ortholog(s) have role in vacuolar acidification, vacuolar proton-transporting V-type ATPase complex assembly and endoplasmic reticulum membrane localization ||	1	0.26	0.24	0.45	0.76	0.71	0.20	0.74	0.88
491	|| orf19.5236 ||  ||  || Ortholog(s) have dehydrodolichyl diphosphate synthase activity, role in protein glycosylation and lipid particle localization ||	1	0.29	0.49	0.58	0.62	0.43	0.03	0.58	0.77
492	|| orf19.2647 || ZCF14 ||  || Putative Zn(II)2Cys6 transcription factor; caspofungin induced ||	1	0.38	0.50	0.19	0.53	-0.03	0.58	0.70	0.67
493	|| orf19.6797 ||  ||  || Ortholog of <i>C. dubliniensis CD36</i> : Cd36_86960, <i>C. parapsilosis CDC317</i> : CPAR2_808800, <i>Candida tenuis NRRL Y-1498</i> : CANTEDRAFT_113621 and <i>Debaryomyces hansenii CBS767</i> : DEHA2F02486g ||	1	0.57	1.05	0.59	0.87	0.13	0.77	0.85	0.85
494	|| orf19.5459 ||  ||  || mRNA polyadenylation regulating protein; Hap43-repressed; transcript is upregulated in RHE model of oral candidiasis and in clinical isolates from HIV+ patients with oral candidiasis; Spider biofilm repressed ||	1	0.33	1.01	0.96	0.64	0.26	0.84	0.80	0.86
495	|| orf19.5620 ||  ||  || Stationary phase enriched protein; Gcn4-regulated; induced by amino acid starvation (3-AT), benomyl or in azole-resistant strain that overexpresses MDR1; flow model biofilm induced; rat catheter biofilm repressed; overlaps orf19.5621 ||	1	0.24	0.73	0.68	0.56	0.29	0.49	0.42	0.65
496	|| orf19.2947 || SNZ1 ||  || Stationary phase protein; vitamin B synthesis; induced byyeast-hypha switch, 3-AT or in azole-resistant strain overexpressing MDR1; soluble in hyphae; regulated by Gcn4, macrophage; Spider biofilm induced; rat catheter biofilm repressed ||	1	0.04	0.69	0.78	0.89	0.34	0.49	0.38	0.71
497	|| orf19.7265 ||  ||  || Putative zinc-finger domain protein with a predicted role in pre-mRNA splicing; Hap43-repressed; Spider biofilm repressed ||	1	0.09	0.69	0.67	0.79	0.24	0.41	0.30	0.60
498	|| orf19.629 || IFD7 ||  || Protein similar to aryl-alcohol dehydrogenases; regulated by Nrg1, Tup1; induced by benomyl treatment or fluconazole exposure over multiple generations; induction correlates with fluconazole resistance; removed from Assembly 20 ||	1	0.78	1.68	2.19	2.76	0.75	1.45	0.75	2.12
499	|| orf19.6837 || FMA1 ||  || Putative oxidoreductase; induced by ciclopirox olamine; upregulation correlates with clinical development of fluconazole resistance; Spider biofilm repressed ||	1	0.84	1.69	1.45	2.40	0.60	1.71	0.80	1.59
500	|| orf19.6229 || CAT1 ||  || Catalase; resistance to oxidative stress, neutrophils, peroxide; role in virulence; regulated by iron, ciclopirox, fluconazole, carbon source, pH, Rim101, Ssn6, Hog1, Hap43, Sfu1, Sef1, farnesol, core stress response; Spider biofilm induced ||	1	0.28	0.77	0.75	0.85	0.32	0.54	0.49	0.83
501	|| orf19.5674 || PGA10 ||  || GPI anchored membrane protein; utilization of hemin and hemoglobin for Fe in host; Rim101 at ph8/hypoxia/ketoconazole/ciclopirox/hypha-induced; required for RPMI biofilm formation, Bcr1-induced in a/a biofilm; rat catheter biofilm repressed ||	1	0.37	1.12	1.05	1.50	0.48	1.05	0.80	1.40
502	|| orf19.5760 || IHD1 ||  || GPI-anchored protein; alkaline, hypha-induced; regulated by Nrg1, Rfg1, Tup1 and Tsa1, Tsa1B in minimal media at 37; oralpharyngeal candidasis induced ; Spider biofilm induced; regulated in Spider biofilms by Tec1, Efg1, Ndt80, Rob1, Brg1 ||	1	0.41	0.88	0.74	0.94	0.23	0.74	0.76	1.03
503	|| orf19.1964 ||  ||  || Protein of unknown function; repressed by fluphenazine treatment; induced by benomyl treatment and in an RHE model; regulated by Nrg1, Tup1 ||	1	0.55	0.98	0.71	1.07	0.23	0.91	0.69	0.97
504	|| orf19.5674 || PGA10 ||  || GPI anchored membrane protein; utilization of hemin and hemoglobin for Fe in host; Rim101 at ph8/hypoxia/ketoconazole/ciclopirox/hypha-induced; required for RPMI biofilm formation, Bcr1-induced in a/a biofilm; rat catheter biofilm repressed ||	1	0.48	1.18	0.85	1.27	0.64	1.15	0.71	1.35
505	|| orf19.1591 || ERG10 ||  || Acetyl-CoA acetyltransferase; role in ergosterol biosynthesis; soluble in hyphae; changes in protein abundance associated with azole resistance; fluconazole or ketoconazole induced; macrophage-downregulated protein; GlcNAc-induced protein ||	1	0.39	0.62	0.64	0.71	0.46	0.74	0.50	0.85
506	|| orf19.1667 ||  ||  || Protein with a predicted SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily domain; Hap43-repressed gene ||	1	0.32	0.85	0.57	0.87	0.41	0.79	0.17	0.78
507	|| orf19.2016 || ERG28 ||  || Ortholog(s) have protein binding, bridging activity, role in ergosterol biosynthetic process and endoplasmic reticulum membrane localization ||	1	0.16	0.60	0.38	1.04	0.56	0.77	0.58	0.72
508	|| orf19.5282 ||  ||  || Protein of unknown function; Hap43-repressed gene; mRNA binds to She3; repressed in hyphae; Efg1 and Efh1 regulated; 5'-UTR intron; induced by Mnl1 under weak acid stress; rat catheter biofilm induced ||	1	0.28	0.30	0.33	0.79	0.53	0.44	0.58	0.60
509	|| orf19.2558 ||  ||  || Has domain(s) with predicted zinc ion binding activity and nucleus localization ||	1	0.43	0.38	0.55	1.08	0.47	0.67	0.77	0.89
510	|| orf19.5953 ||  ||  || C2H2 transcription factor; predicted regulator of ribosomal protein and biogenesis genes; possibly essential, disruptants not obtained by UAU1 method; rat catheter biofilm induced ||	1	0.47	0.31	0.59	0.93	0.39	0.46	0.62	0.75
511	|| orf19.6254 || ANT1 ||  || Peroxisomal adenine nucleotide transporter; role in beta-oxidation of medium-chain fatty acid and peroxisome proliferation; rat catheter biofilm induced ||	1	0.33	0.26	0.24	0.63	0.23	0.52	0.59	0.66
512	|| orf19.5636 || RBT5 ||  || GPI-linked cell wall protein; hemoglobin utilization; Rfg1, Rim101, Tbf1, Fe regulated; Sfu1, Hog1, Tup1, serum, alkaline pH, antifungal drugs, geldamycin repressed; Hap43 induced; required for RPMI biofilms; Spider biofilm induced ||	1	0.39	0.54	0.29	0.89	0.43	0.84	0.81	0.97
513	|| orf19.2400 ||  ||  || Ortholog(s) have role in mRNA splicing, via spliceosome, maturation of SSU-rRNA, positive regulation of ATPase activity, positive regulation of helicase activity ||	1	0.56	0.91	0.63	1.00	0.84	0.33	0.49	0.51
514	|| orf19.2400 ||  ||  || Ortholog(s) have role in mRNA splicing, via spliceosome, maturation of SSU-rRNA, positive regulation of ATPase activity, positive regulation of helicase activity ||	1	0.56	0.91	0.63	1.00	0.84	0.33	0.49	0.51
515	|| orf19.7267 || SAM35 ||  || Predicted component of the sorting and assembly machinery (SAM complex) of the mitochondrial outer membrane, involved in protein import into mitochondria ||	1	0.61	0.51	0.56	0.70	0.48	0.32	0.43	0.39
516	|| orf19.1553 || ENT3 ||  || Putative epsin; induced during the mating process; transcript is upregulated in an RHE model of oral candidiasis ||	1	1.07	0.94	1.11	1.07	0.98	0.49	0.57	0.94
517	|| orf19.7328 ||  ||  || Protein with a Staphylococcal nuclease domain; transcript regulated by Mig1 and Tup1; flow model and Spider biofilm repressed ||	1	0.33	0.58	0.94	0.68	0.54	0.37	0.42	0.60
518	|| orf19.4330 ||  ||  || Ortholog of <i>C. dubliniensis CD36</i> : Cd36_52790, <i>Candida tropicalis MYA-3404</i> : CTRG_05968 and <i>Candida albicans WO-1</i> : CAWG_04684 ||	1	0.76	1.04	1.18	0.93	0.75	0.59	0.51	0.86
519	|| orf19.4330 ||  ||  || Ortholog of <i>C. dubliniensis CD36</i> : Cd36_52790, <i>Candida tropicalis MYA-3404</i> : CTRG_05968 and <i>Candida albicans WO-1</i> : CAWG_04684 ||	1	0.76	1.04	1.18	0.93	0.75	0.59	0.51	0.86
520	|| orf19.5713 || YMX6 ||  || Putative NADH dehydrogenase; macrophage-downregulated gene; induced by nitric oxide; rat catheter biofilm induced ||	1	0.69	1.38	1.55	1.00	0.64	0.68	0.75	0.87
521	|| orf19.5693 ||  ||  || Subunit of the GPI (glycosylphosphatidylinositol):protein transamidase complex; removes the GPI-anchor signal and attaches GPI to proteins in the ER; Spider biofilm repressed ||	1	0.59	0.60	0.71	0.52	0.19	0.53	0.40	0.48
522	|| orf19.6023 ||  ||  || Protein with a predicted multidrug transporter domain; Hap43-repressed gene ||	1	0.32	0.68	1.13	0.61	0.74	0.84	0.42	0.54
523	|| orf19.4015 || CAG1 ||  || heterotrimeric G protein alpha subunit; positive role in mating pheromone response; opaque-enriched transcript; transcript repressed by MTLa1-MTLalpha2; regulated by hemoglobin-responsive Hbr1 via MTL genes; rat catheter biofilm repressed ||	1	0.21	1.04	0.78	0.59	0.73	0.73	0.24	0.44
524	|| orf19.345 ||  ||  || Succinate semialdehyde dehydrogenase; for utilization of gamma-aminobutyrate (GABA) as a nitrogen source; part of 4-aminobutyrate and glutamate degradation pathways; rat catheter biofilm induced ||	1	0.71	0.36	0.56	0.73	0.45	0.63	0.46	0.33
525	|| orf19.1631 || ERG6 ||  || Delta(24)-sterol C-methyltransferase, converts zymosterol to fecosterol, ergosterol biosynthesis; mutation confers nystatin resistance; Hap43, GlcNAc-, fluconazole-induced; upregulated in azole-resistant strain; Spider biofilm repressed ||	1	0.69	0.51	1.07	0.59	0.84	0.85	0.76	0.95
526	|| orf19.2176 || IFM3 ||  || Protein with a 2-hydroxyacid dehydrogenase catalytic domain; Hap43-repressed; Plc1-regulated; overlaps orf19.2177 ||	1	0.67	0.47	0.45	0.49	0.70	0.73	0.87	0.81
527	|| orf19.2175 ||  ||  || Putative mitochondrial cell death effector; induced by nitric oxide; Spider biofilm induced; rat catheter biofilm repressed ||	1	0.63	0.34	0.56	0.67	0.82	0.63	0.81	0.79
528	|| orf19.5454 || DAL1 ||  || Putative allantoinase; transcript regulated by Nrg1 and Mig1; macrophage/pseudohyphal-repressed ||	1	1.07	0.37	0.88	1.22	1.46	1.27	1.47	0.91
529	|| orf19.1344 ||  ||  || Protein of unknown function; fluconazole-induced; Spider biofilm induced ||	1	2.22	0.35	1.56	0.88	1.68	1.34	1.81	1.07
530	|| orf19.3434 || TRY5 ||  || Zn(II)2Cys6 transcription factor; regulator of yeast form adherence; required for yeast cell adherence to silicone substrate ||	1	0.69	0.17	0.50	0.35	0.68	0.35	1.06	0.63
531	|| orf19.5741 || ALS1 ||  || Cell-surface adhesin; adhesion, virulence, immunoprotective roles; band at hyphal base; Rfg1, Ssk1, Spider biofilm induced; flow model biofilm repressed; CAI-4 strain background effects; promoter bound Bcr1, Tec1, Efg1, Ndt80, and Brg1 ||	1	1.37	-0.15	0.40	1.15	1.48	1.21	1.77	1.08
532	|| orf19.1405 || PHO13 ||  || Putative 4-nitrophenylphosphatase; Hap43p-repressed gene; transcription is regulated upon yeast-hyphal switch ||	1	0.46	-0.25	0.38	0.63	0.70	0.59	0.48	0.44
533	|| orf19.4167 ||  ||  || Protein of unknown function; Spider biofilm induced ||	1	0.93	-0.44	1.13	1.13	1.51	0.79	1.52	0.77
534	|| orf19.5291 ||  ||  || Ortholog(s) have role in phospholipid biosynthetic process and endoplasmic reticulum localization ||	1	0.60	-0.14	0.74	0.30	0.72	0.56	0.41	0.49
535	|| orf19.5319 ||  ||  || Predicted ORF from Assembly 19; merged with orf19.5318 in Assembly 20 ||	1	0.78	0.54	0.64	0.19	1.09	-0.09	0.80	0.68
536	|| orf19.7444 ||  ||  || Ortholog(s) have cytoplasm, holo TFIIH complex localization ||	1	0.25	0.66	0.34	0.21	1.00	-0.22	1.24	0.72
537	|| orf19.3937 ||  ||  || Ortholog(s) have protein phosphatase type 2A regulator activity, role in TOR signaling cascade, cellular response to nitrogen starvation and cytosol, nucleus localization ||	1	0.46	0.68	0.11	0.53	0.47	-0.11	0.85	0.66
538	|| orf19.4041 || PEX4 ||  || Putative peroxisomal ubiquitin conjugating enzyme; regulated by Sef1, Sfu1, and Hap43; rat catheter biofilm induced; Spider biofilm induced ||	1	0.88	0.37	0.30	1.25	0.93	0.54	1.68	1.20
539	|| orf19.3670 || GAL1 ||  || Galactokinase; galactose, Mig1, Tup1, Hap43 regulated; fluconazole, ketoconazole-induced; stationary phase enriched protein; GlcNAc-induced protein; farnesol, hypoxia-repressed in biofilm; rat catheter and Spider biofilm induced ||	1	0.43	0.12	0.28	0.53	0.54	-0.00	1.02	0.68
540	|| orf19.6027 ||  ||  || Ortholog of <i>C. dubliniensis CD36</i> : Cd36_00740, <i>C. parapsilosis CDC317</i> : CPAR2_110170, <i>Candida tenuis NRRL Y-1498</i> : CANTEDRAFT_133175 and <i>Debaryomyces hansenii CBS767</i> : DEHA2D09724g ||	1	0.38	0.41	0.62	0.71	1.05	0.06	1.73	0.62
541	|| orf19.2108 || SOD6 ||  || Copper- and zinc-containing superoxide dismutase; gene family includes SOD1, SOD4, SOD5, and SOD6; gene may contain an intron; Hap43-repressed; flow model and rat catheter biofilm induced ||	1	0.23	-0.12	0.27	0.56	0.72	-0.25	1.24	0.72
542	|| orf19.5523 ||  ||  || Ortholog of <i>C. dubliniensis CD36</i> : Cd36_62780, <i>C. parapsilosis CDC317</i> : CPAR2_601690, <i>Candida tenuis NRRL Y-1498</i> : CANTEDRAFT_113271 and <i>Debaryomyces hansenii CBS767</i> : DEHA2A06644g ||	1	-0.02	-0.03	0.32	0.27	0.37	-0.13	0.68	0.55
543	|| orf19.3672 || GAL10 ||  || UDP-glucose 4-epimerase; galactose utilization; mutant has cell wall defects and increased filamentation; GlcNAc-, fluconazole- and ketoconazole-induced; stationary phase enriched protein; rat catheter and flow model biofilm induced ||	1	-0.01	0.39	0.18	0.59	0.43	0.18	0.70	0.68
544	|| orf19.5875 || VAM3 ||  || Predicted target membrane receptor (t-SNARE) involved in vacuolar transport, endocytosis, and secretion; required for biofilm formation in RPMI-1640 and for virulence; rat catheter biofilm repressed ||	1	-0.05	0.63	0.13	0.82	0.17	0.03	0.63	0.75
545	|| orf19.6033 || CMP1 ||  || Catalytic subunit of calcineurin (Ca[2+]-calmodulin-regulated S/T protein phosphatase); required for wild-type virulence, resistance to high pH, Na(+), Li(+), Mn(2+), and fluconazole tolerance; micafungin is fungicidal to null mutant ||	1	0.48	0.25	0.22	0.83	0.75	0.57	0.12	0.33
546	|| orf19.3631 || STN1 ||  || Protein involved in telomere maintenance; forms a complex with Ten1p ||	1	0.63	0.48	0.63	0.54	0.78	0.26	-0.05	0.32
547	|| orf19.3622 || ANP1 ||  || Putative mannosyltransferase of Golgi; member of Mnn9p family; similar to S. cerevisiae Anp1p; fungal-specific (no human or murine homolog) ||	1	0.95	0.62	0.60	0.26	0.40	0.45	0.18	-0.01
548	|| orf19.1327 || RBT1 ||  || Cell wall protein with similarity to Hwp1; required for virulence; predicted glycosylation; fluconazole, Tup1 repressed; farnesol, alpha factor, serum, hyphal and alkaline induced; Rfg1, Rim101-regulated ||	1	0.89	0.67	0.24	0.17	0.64	0.90	0.13	0.23
549	|| orf19.1327 || RBT1 ||  || Cell wall protein with similarity to Hwp1; required for virulence; predicted glycosylation; fluconazole, Tup1 repressed; farnesol, alpha factor, serum, hyphal and alkaline induced; Rfg1, Rim101-regulated ||	1	0.89	0.67	0.24	0.17	0.64	0.90	0.13	0.23
550	|| orf19.2285 ||  ||  || Protein of unknown function; transcription induced by benomyl treatment ||	1	0.73	1.33	0.88	0.57	0.86	1.26	1.05	0.00
551	|| orf19.1050 ||  ||  || Ortholog of <i>S. cerevisiae</i> : YMR087W, <i>C. glabrata CBS138</i> : CAGL0J01397g, <i>C. dubliniensis CD36</i> : Cd36_03920, <i>C. parapsilosis CDC317</i> : CPAR2_107150 and <i>Pichia stipitis Pignal</i> : PICST_61741 ||	1	0.43	1.32	-0.28	1.70	0.94	1.52	0.70	0.91
552	|| orf19.1616 || FGR23 ||  || Protein of unknown function; repressed by a1/alpha2 in white-phase cells, a-specific, alpha factor-induced; Hap43-repressed; flow model biofilm induced; Tn mutation affects filamentous growth; ||	1	-0.49	1.30	0.59	1.23	0.75	0.59	0.28	1.23
553	|| orf19.5145 || SSP96 ||  || Putative flavin-containing monooxygenase; F-12/CO2 early biofilm induced ||	1	-0.13	0.90	0.61	1.20	0.38	0.32	0.36	1.07
554	|| orf19.4923 ||  ||  || Predicted membrane transporter; sugar porter (SP) family member, major facilitator superfamily; caspofungin induced; Spider biofilm induced ||	1	0.60	1.25	0.53	0.92	0.18	0.17	0.43	0.92
555	|| orf19.2740 ||  ||  || Ortholog(s) have 5'-flap endonuclease activity ||	1	0.35	0.69	0.56	0.55	0.13	0.16	0.10	0.51
556	|| orf19.3607 ||  ||  || Ortholog of <i>C. dubliniensis CD36</i> : Cd36_22860, <i>C. parapsilosis CDC317</i> : CPAR2_806540, <i>Candida tenuis NRRL Y-1498</i> : CANTEDRAFT_108823 and <i>Debaryomyces hansenii CBS767</i> : DEHA2B13596g ||	1	1.94	3.33	1.70	3.91	0.51	2.69	-1.41	3.80
557	|| orf19.6501 ||  ||  || Ortholog of <i>C. dubliniensis CD36</i> : Cd36_71960, <i>Pichia stipitis Pignal</i> : psti_CGOB_00136, <i>Spathaspora passalidarum NRRL Y-27907</i> : SPAPADRAFT_63786 and <i>Candida tropicalis MYA-3404</i> : CTRG_05049 ||	1	0.64	4.26	1.57	4.20	0.47	3.17	0.04	3.02
558	|| orf19.6501 ||  ||  || Ortholog of <i>C. dubliniensis CD36</i> : Cd36_71960, <i>Pichia stipitis Pignal</i> : psti_CGOB_00136, <i>Spathaspora passalidarum NRRL Y-27907</i> : SPAPADRAFT_63786 and <i>Candida tropicalis MYA-3404</i> : CTRG_05049 ||	1	0.64	4.26	1.57	4.20	0.47	3.17	0.04	3.02
559	|| orf19.6148 ||  ||  || Homolog of nuclear distribution factor NudE, NUDEL; regulates dynein targeting to microtubule plus ends; flow model biofilm repressed ||	1	0.58	4.08	1.79	4.25	0.91	2.95	-0.21	2.46
560	|| orf19.751 ||  ||  || Ortholog of <i>C. dubliniensis CD36</i> : Cd36_04660, <i>Candida tropicalis MYA-3404</i> : CTRG_04484 and <i>Candida albicans WO-1</i> : CAWG_00904 ||	1	0.23	1.36	0.67	0.94	-0.00	0.76	0.34	1.36
561	|| orf19.1345 || LIP8 ||  || Secreted lipase, member of a differentially expressed lipase gene family with possible roles in nutrition and/or in creating an acidic microenvironment; LIP5 and LIP8 are expressed at all stages of both mucosal and systemic infection ||	1	0.51	0.96	0.66	0.69	-0.25	0.58	0.38	1.00
562	|| orf19.6342 ||  ||  || Ortholog of <i>C. dubliniensis CD36</i> : Cd36_11980, <i>C. parapsilosis CDC317</i> : CPAR2_201330, <i>Candida tenuis NRRL Y-1498</i> : CANTEDRAFT_114815 and <i>Debaryomyces hansenii CBS767</i> : DEHA2G10032g ||	1	0.92	1.97	1.71	3.21	-0.84	2.22	1.33	3.31
563	|| orf19.3151 ||  ||  || Has domain(s) with predicted catalytic activity, coenzyme binding activity and role in cellular metabolic process ||	1	-0.25	0.49	0.62	0.57	0.19	-0.21	0.69	0.17
564	|| orf19.1325 || ECM38 ||  || Putative gamma-glutamyltransferase; alkaline upregulated; Spider biofilm induced; possibly an essential gene, disruptants not obtained by UAU1 method ||	1	0.11	0.28	0.72	0.57	-0.12	0.32	0.60	0.44
565	|| orf19.2496 || ATO2 ||  || Putative fungal-specific transmembrane protein; fluconazole repressed, Hap43-repressed; flow model biofilm induced; Spider biofilm induced ||	1	0.05	0.38	0.78	0.80	-0.34	0.64	0.44	0.52
566	|| orf19.7112 || FRP2 ||  || Putative ferric reductase; alkaline induced by Rim101; fluconazole-downregulated; upregulated in the presence of human neutrophils; possibly adherence-induced; regulated by Sef1, Sfu1, and Hap43 ||	1	-0.38	0.52	0.65	0.60	0.12	0.13	0.18	0.33
567	|| orf19.1307 ||  ||  || Predicted membrane protein; rat catheter biofilm induced ||	1	-0.07	1.53	1.66	0.77	-0.24	0.26	0.70	1.06
568	|| orf19.3131 || OYE32 ||  || NAD(P)H oxidoreductase family protein; induced by nitric oxide, amphotericin B, oxidative stress via Cap1; upregulation associated with MDR1 overexpression or benomyl treatment; macrophage-downregulated protein; Spider biofilm induced ||	1	0.06	1.32	1.23	0.72	-0.01	0.22	0.39	0.83
569	|| orf19.4894 ||  ||  || Protein with similarity to S. cerevisiae Yer010cp, a protein of unknown function belonging to the prokaryotic RraA family; repressed by benomyl; Hap43-induced; Spider biofilm induced ||	1	-0.02	0.91	0.71	0.58	-0.06	-0.00	0.30	0.41
570	|| orf19.1421 ||  ||  || Ortholog(s) have ureidoglycolate hydrolase activity and cytosol, nucleus localization ||	1	-0.06	0.83	0.73	0.59	0.07	0.01	0.30	0.38
571	|| orf19.2262 ||  ||  || Protein similar to quinone oxidoreductases; induced by benomyl treatment, nitric oxide; oxidative stress-induced via Cap1; stationary-phase enriched protein; Spider biofilm induced ||	1	-0.23	0.92	0.92	0.78	-0.17	0.06	0.40	0.68
572	|| orf19.7676 || XYL2 ||  || D-xylulose reductase; immunogenic in mice; soluble protein in hyphae; induced by caspofungin, fluconazole, Hog1 and during cell wall regeneration; Mnl1-induced in weak acid stress; stationary phase enriched; flow model biofilm induced ||	1	-0.27	1.00	0.91	0.68	-0.39	0.20	0.25	0.65
573	|| orf19.1369 ||  ||  || Protein with predicted peptidase domains; Hap43-repressed gene ||	1	0.08	0.80	0.92	0.68	-0.19	0.24	-0.11	0.44
574	|| orf19.5784 || AMO1 ||  || Putative peroxisomal copper amine oxidase ||	1	-0.05	0.87	0.73	0.57	-0.11	-0.51	0.15	0.80
575	|| orf19.268 ||  ||  || Ortholog(s) have role in transcription-coupled nucleotide-excision repair and Ddb1-Ckn1 complex, cytosol localization ||	1	-0.10	0.52	0.88	0.55	-0.00	-0.57	0.39	0.58
576	|| orf19.3910 ||  ||  || Has domain(s) with predicted RNA binding, ribonuclease T2 activity ||	1	-0.16	1.11	1.54	1.24	-0.35	-0.81	0.72	0.76
577	|| orf19.7281 || PDK2 ||  || Putative pyruvate dehydrogenase kinase; mutation confers hypersensitivity to amphotericin B ||	1	-0.12	0.35	0.56	0.69	-0.07	-0.28	0.25	0.38
578	|| orf19.7579 || FGR34 ||  || Protein lacking an ortholog in S. cerevisiae; transposon mutation affects filamentous growth ||	1	-0.02	0.45	0.58	0.60	0.04	-0.13	0.32	0.27
579	|| orf19.4979 || KNS1 ||  || Protein kinase involved in negative regulation of PolIII transcription; effector kinase of the TOR signaling pathway, phosphorylates Rpc53p to regulate ribosome and tRNA biosynthesis; Spider and flow model biofilm induced ||	1	-0.43	0.84	1.00	1.11	-0.23	-0.24	0.51	1.06
580	|| orf19.6196 ||  ||  || Component of the SWI/SNF and RSC chromatin remodeling complexes; suggested role in chromosome maintenance; Spider biofilm induced ||	1	-0.27	0.64	0.74	0.72	-0.05	-0.14	0.28	0.74
581	|| orf19.4390 ||  ||  || Protein of unknown function; repressed by alpha pheromone in SpiderM medium; transcript induced by Mnl1 under weak acid stress ||	1	-0.29	0.45	0.73	0.64	-0.08	-0.10	0.22	0.45
582	|| orf19.5102 || PLB5 ||  || Putative GPI-linked phospholipase B, fungal-specific (no mammalian homolog); null mutation eliminates cell-associated phospholipase A2 activity and attenuates virulence; fluconazole-repressed; flow model biofilm repressed ||	1	-0.23	0.65	0.90	0.54	-0.33	-0.16	0.28	0.54
583	|| orf19.6048 ||  ||  || Protein of unknown function; Spider biofilm induced ||	1	-0.30	0.39	0.55	0.58	-0.26	-0.06	0.55	0.68
584	|| orf19.2838 ||  ||  || Protein of unknown function; mutation confers hypersensitivity to amphotericin B; flow model biofilm induced ||	1	-0.42	0.54	0.60	0.72	-0.30	-0.27	0.66	0.93
585	|| orf19.4055 ||  ||  || Protein similar to S. cerevisiae Ybr075wp; transposon mutation affects filamentous growth; clade-associated gene expression ||	1	-0.51	0.15	0.59	0.56	-0.10	-0.46	0.60	0.69
586	|| orf19.540 ||  ||  || Has domain(s) with predicted palmitoyl-(protein) hydrolase activity and role in cellular protein modification process ||	1	-0.14	0.28	0.79	0.47	0.07	-0.53	0.77	0.88
587	|| orf19.860 || BMT8 ||  || Putative beta-mannosyltransferase, member of a 9-gene family including characterized BMT genes with roles in beta-1,2-mannosylation of cell wall phosphopeptidomannan; transposon insertion in promoter region causes decreased colony wrinkling ||	1	-0.00	0.46	0.69	0.38	-0.02	-0.30	0.57	1.02
588	|| orf19.2154 || HXK1 ||  || N-acetylglucosamine (GlcNAc) kinase; involved in GlcNAc utilization; required for wild-type hyphal growth and mouse virulence; GlcNAc-induced transcript; induced by alpha pheromone in SpiderM medium ||	1	0.39	0.44	0.67	0.65	-0.12	0.04	0.42	0.58
589	|| orf19.2313 ||  ||  || Putative ortholog of S. cerevisiae Pex32 a peroxisomal integral membrane protein with a role in negative regulation of peroxisome size; Hap43-repressed gene ||	1	0.35	0.64	0.75	0.75	-0.16	-0.02	0.48	0.80
590	|| orf19.2565 ||  ||  || Predicted intermediate filament protein; required for nuclear and mitochondrial transmission to daughter buds in S. cerevisiae; Spider biofilm induced ||	1	0.08	0.41	0.54	0.66	-0.35	-0.13	0.35	0.60
591	|| orf19.6517 || RAD14 ||  || Putative DNA repair protein; transcription is regulated upon yeast-hyphal switch; flucytosine repressed ||	1	-0.03	0.58	0.65	0.69	-0.16	0.02	0.31	0.77
592	|| orf19.5585 || SAP5 ||  || Secreted aspartyl proteinase; sap4,5,6 triple null defective in utilization of protein as N source; virulence role effected by URA3; expressed during infection; mRNA localized to hyphal tip via She3; rat catheter and Spider biofilm induced ||	1	-0.02	1.21	0.90	1.54	-0.08	-0.23	0.95	1.48
593	|| orf19.2313 ||  ||  || Putative ortholog of S. cerevisiae Pex32 a peroxisomal integral membrane protein with a role in negative regulation of peroxisome size; Hap43-repressed gene ||	1	0.47	0.70	0.45	1.17	-0.23	-0.34	0.73	0.88
594	|| orf19.2423 || ZCF11 ||  || Zn(II)2Cys6 transcription factor; required for wild-type filamentous growth; mRNA binds She3 ||	1	-0.01	0.32	0.42	0.90	-0.18	0.21	0.56	0.97
595	|| orf19.1587 || HGT20 ||  || Putative glucose transporter of the major facilitator superfamily; the C. albicans glucose transporter family comprises 20 members; 12 probable membrane-spanning segments; regulated by Nrg1 ||	1	0.00	0.24	0.30	0.59	-0.14	0.08	0.66	0.82
596	|| orf19.4174 ||  ||  || Ortholog(s) have nicotinamide riboside transmembrane transporter activity, role in nicotinamide riboside transport, transmembrane transport and fungal-type vacuole membrane localization ||	1	0.11	0.39	0.53	0.59	-0.09	0.09	0.59	0.67
597	|| orf19.1587 || HGT20 ||  || Putative glucose transporter of the major facilitator superfamily; the C. albicans glucose transporter family comprises 20 members; 12 probable membrane-spanning segments; regulated by Nrg1 ||	1	0.36	0.14	0.57	0.68	-0.04	-0.01	0.83	0.83
598	|| orf19.910 || PRP3 ||  || Predicted splicing factor, component of the U4/U6-U5 snRNP complex; Hap43-induced gene; rat catheter biofilm induced ||	1	0.20	0.21	0.18	0.44	0.12	0.05	0.58	0.66
599	|| orf19.516 ||  ||  || <I>S. cerevisiae</I> ortholog Rft1p has role in glycolipid translocation, protein N-linked glycosylation and localizes to endoplasmic reticulum membrane; regulated by Sef1p-, Sfu1p-, and Hap43p ||	1	0.12	0.13	0.20	0.48	-0.00	0.28	0.63	0.60
600	|| orf19.5501 || YAF9 ||  || Subunit of the NuA4 histone acetyltransferase complex; transcript regulated by Mig1; possibly an essential gene, disruptants not obtained by UAU1 method ||	1	-0.09	0.54	0.55	0.56	-0.43	0.08	0.74	0.38
601	|| orf19.859 ||  ||  || Predicted ORF from Assembly 19; merged with orf19.857 in Assembly 20 ||	1	0.37	0.84	1.33	0.93	-0.80	-0.56	0.58	0.27
602	|| orf19.6995 || ATO6 ||  || Putative fungal-specific transmembrane protein ||	1	-0.02	0.11	0.91	0.71	-0.69	-0.17	0.58	0.68
603	|| orf19.6993 || GAP2 ||  || General amino acid permease; ketoconazole, flucytosine repressed; Ssy1-dependent histidine induction; regulated by Nrg1, Tup1; colony morphology-related gene regulation by Ssn6; Spider and flow model biofilm induced ||	1	-0.67	0.55	1.12	0.75	-0.78	-0.45	0.14	0.69
604	|| orf19.2839 || CIRT4B ||  || Cirt family transposase; transcript repressed in an azole-resistant strain that overexpresses CDR1 and CDR2; Hap43-repressed; flow model biofilm induced ||	1	-0.35	0.44	0.70	0.36	-0.64	-0.66	0.49	0.42
605	|| orf19.1275 || GAT1 ||  || GATA-type transcription factor; regulator of nitrogen utilization; required for nitrogen catabolite repression and utilization of isoleucine, tyrosine and tryptophan N sources; required for virulence in a mouse systemic infection model ||	1	-0.60	0.83	0.70	1.02	-1.01	0.05	-0.09	1.43
606	|| orf19.7260 ||  ||  || Protein with a predicted NADP-dependent oxidoreductase or aldo-keto reductase domain; Hap43-repressed; Spider biofilm repressed ||	1	-0.33	1.02	0.54	1.11	-0.54	0.52	-0.12	0.80
607	|| orf19.711 ||  ||  || Protein of unknown function; induced by nitric oxide; predicted ORF from Assembly 19; removed from Assembly 20; restored based on transcription data ||	1	-0.12	1.00	0.70	1.02	-0.35	0.53	0.19	0.22
608	|| orf19.4833 || MLS1 ||  || Malate synthase; glyoxylate cycle enzyme; no mammalian homolog; regulated upon white-opaque switch; phagocytosis, strong oxidative stress induced; stationary phase enriched; flow model biofilm repressed; rat catheter, Spider biofilm induced ||	1	-0.27	1.09	0.95	0.57	-0.28	0.04	-0.02	0.37
609	|| orf19.2344 || ASR1 ||  || Heat shock protein; transcript regulated by cAMP, osmotic stress, ciclopirox olamine, ketoconazole; repressed by Cyr1, Ras1; colony morphology-related regulated by Ssn6; stationary phase enriched; Hap43-induced; Spider biofilm induced ||	1	-0.80	1.69	1.04	0.84	-0.78	0.05	-0.11	0.32
610	|| orf19.4229 ||  ||  || Putative polyphosphate phosphatase; role in hydrolysis of diphosphorylated inositol polyphosphates and diadenosine polyphosphates; Spider biofilm induced ||	1	-1.24	0.82	1.02	0.65	-0.26	0.11	-0.08	0.49
611	|| orf19.5169 ||  ||  || Ortholog(s) have cytosol, nucleus localization ||	1	-0.27	0.96	1.26	0.98	0.61	0.53	-0.72	0.71
612	|| orf19.3121 || GST1 ||  || Putative glutathione S-transferase; upregulated in the presence of human neutrophils; expression is regulated upon white-opaque switching; increased transcription is observed upon benomyl treatment ||	1	-0.37	0.14	1.29	0.69	0.08	0.65	-0.07	0.44
613	|| orf19.5046 || RAM1 ||  || Protein that acts in prenylation; transcription is alpha-factor induced; regulated in response to lovastatin and fluconazole; Hap43p-repressed gene ||	1	0.03	-0.12	0.54	0.58	0.02	0.02	-0.17	-0.07
614	|| orf19.695 || RGS2 ||  || Protein of RGS superfamily; mutants are viable; rat catheter and Spider biofilm induced ||	1	-0.08	-0.29	0.59	1.38	-0.59	-0.90	0.06	0.68
615	|| orf19.190 ||  ||  || Ortholog(s) have role in endoplasmic reticulum organization, histone exchange and Swr1 complex, mitochondrion localization ||	1	0.24	0.17	0.55	0.63	0.34	-0.53	0.18	0.01
616	|| orf19.5270 ||  ||  || Protein of unknown function; rat catheter biofilm induced ||	1	0.10	0.52	1.00	0.59	-0.31	-1.18	0.90	0.42
617	|| orf19.5588 || PGA60 ||  || Putative GPI-anchored adhesin-like protein; hyphal-induced expression ||	1	-0.32	2.20	0.73	1.25	-0.03	-2.06	0.07	2.31
618	|| orf19.1395 ||  ||  || Ortholog(s) have inorganic phosphate transmembrane transporter activity, role in phosphate ion transport, transmembrane transport and mitochondrion localization ||	1	0.20	0.96	0.61	0.87	0.32	-0.57	-0.20	0.82
619	|| orf19.1728 ||  ||  || Ortholog of <i>C. dubliniensis CD36</i> : Cd36_81190, <i>C. parapsilosis CDC317</i> : CPAR2_503840, <i>Debaryomyces hansenii CBS767</i> : DEHA2A09042g and <i>Pichia stipitis Pignal</i> : PICST_42519 ||	1	0.15	2.54	1.07	1.71	0.05	-2.37	-1.42	0.70
620	|| orf19.7193 ||  ||  || Specificity factor required for ubiquitination; role in protein targeting to vacuole; involved in ubiquitin-dependent protein catabolism via the multivesicular body sorting pathway; Spider biofilm induced ||	1	0.78	0.60	-0.07	0.10	0.37	-0.33	-0.03	-0.41
621	|| orf19.3746 || IFC1 ||  || Oligopeptide transporter; induced upon phagocytosis by macrophage; macrophage/pseudohyphal-repressed after 16h; fluconazole-induced; virulence-group-correlated expression; Hap43-repressed ||	1	0.92	0.86	-0.16	-0.12	0.40	-0.53	0.30	-0.27
622	|| orf19.3976 ||  ||  || Ortholog(s) have structural constituent of cytoskeleton activity, role in establishment of mitotic spindle orientation, nuclear migration and astral microtubule, cell cortex, dynactin complex, spindle pole body localization ||	1	0.61	1.02	-0.41	-0.13	0.68	0.05	0.57	-0.03
623	|| orf19.6950 ||  ||  || Putative vacuolar membrane transporter for cationic amino acids; Spider biofilm induced ||	1	0.55	1.13	-0.13	-0.02	0.58	0.29	0.09	-0.01
624	|| orf19.4276 ||  ||  || Predicted ORF from Assembly 19; merged with orf19.4275 in Assembly 20 ||	1	0.82	1.32	1.13	-0.69	0.84	0.79	0.23	0.04
625	|| orf19.6975 || YST1 ||  || Ribosome-associated protein; antigenic in mice; complements S. cerevisiae yst1 yst2 mutant; similar to laminin receptor; predicted S/T phosphorylation, N-glycosylation, myristoylation, Hap43-, Gcn4-regulated; Spider biofilm repressed ||	1	1.04	0.30	0.59	-1.42	1.29	0.57	-0.28	0.69
626	|| orf19.3926 || RNY11 ||  || Ortholog(s) have endoribonuclease activity, role in RNA catabolic process, apoptotic process, cell morphogenesis and cytosol, extracellular region, vacuole localization ||	1	0.65	3.92	0.21	2.49	-0.46	3.15	-1.96	0.06
627	|| orf19.4505 || ADH3 ||  || Putative NAD-dependent (R,R)-butanediol dehydrogenase; regulated by white-opaque switch; induced by nitric oxide independent of Yhb1; Spider biofilm induced ||	1	-0.95	0.84	-0.66	-0.73	-0.55	0.47	-0.27	-0.34
628	|| orf19.3749 || IFC3 ||  || Oligopeptide transporter; transcript induced by macrophage phagocytosis, BSA or peptides; fluconazole-induced; induced by Rim101 at pH 8; virulence-group-correlated expression; Hap43-repressed; Spider biofilm induced ||	1	-0.83	0.78	0.48	0.14	-0.83	-0.68	0.05	0.10
629	|| orf19.1656 ||  ||  || Protein with a predicted FYVE/PHD zinc finger domain; Hap43-repressed; Spider biofilm induced ||	1	-1.35	0.57	0.35	-0.61	-0.68	-0.46	-0.66	-0.67
630	|| orf19.7053 || GAC1 ||  || Putative regulatory subunit of ser/thr phosphoprotein phosphatase 1; fluconazole-induced; caspofungin repressed; transcript induced by Mnl1 under weak acid stress; regulated by Nrg1, Tup1; Spider and flow model biofilm induced ||	1	-0.50	0.90	0.31	-0.47	-0.85	-0.72	-0.77	-0.70
631	|| orf19.7053 || GAC1 ||  || Putative regulatory subunit of ser/thr phosphoprotein phosphatase 1; fluconazole-induced; caspofungin repressed; transcript induced by Mnl1 under weak acid stress; regulated by Nrg1, Tup1; Spider and flow model biofilm induced ||	1	-0.50	0.90	0.31	-0.47	-0.85	-0.72	-0.77	-0.70
632	|| orf19.113 || CIP1 ||  || Possible oxidoreductase; transcript induced by cadmium but not other heavy metals, heat shock, yeast-hypha switch, oxidative stress (via Cap1), or macrophage interaction; stationary phase enriched protein; Spider biofilm induced ||	1	-0.61	1.20	0.17	-0.46	-0.87	-1.14	-0.60	-0.41
633	|| orf19.4135 || PRC2 ||  || Putative carboxypeptidase; induced by human neutrophils; Spider biofilm induced ||	1	-0.68	1.15	-0.16	-0.52	-1.24	-1.01	-0.74	-0.33
634	|| orf19.4530.1 ||  ||  || Protein of unknown function; regulated by Nrg1, Tup1; Spider and flow model biofilm induced ||	1	-1.35	1.10	-0.13	-0.09	-1.48	-0.79	-0.99	-0.10
635	|| orf19.769 || IFE1 ||  || Putative medium-chain alcohol dehydrogenase; rat catheter and Spider biofilm repressed ||	1	-1.11	0.80	-0.31	-0.35	-1.37	-0.63	-1.47	-0.38
636	|| orf19.4943 || PSA2 ||  || Mannose-1-phosphate guanyltransferase; Hap43, macrophage-repressed; stationary phase enriched protein; Spider biofilm induced; rat catheter biofilm repressed ||	1	-0.76	0.43	-0.22	-0.43	-1.09	-0.95	-0.33	0.04
637	|| orf19.2172 || ARA1 ||  || D-Arabinose dehydrogenase; dehydro-D-arabinono-1,4-lactone synthesis; active on D-arabinose, L-fucose, L-xylose, L-galactose; inhibited by metal ions, thiol group-specific reagents; induced on polystyrene adherence; Spider biofilm induced ||	1	-0.72	0.31	0.40	-0.05	-0.77	-1.21	-0.41	-0.50
638	|| orf19.5775 ||  ||  || Predicted ORF overlapping the Major Repeat Sequence on chromosome 6; member of a family encoded by FGR6-related genes in the RB2 repeat sequence; rat catheter biofilm repressed ||	1	-0.15	0.25	0.16	-0.34	-0.71	-1.39	-0.09	-0.83
639	|| orf19.247 ||  ||  || Ortholog(s) have role in endosome organization, regulation of protein localization and BLOC-1 complex, endosome localization ||	1	-0.42	-0.53	0.11	-0.04	-0.82	-1.22	-0.57	0.44
640	|| orf19.1484 ||  ||  || Ortholog of S, cerevisiae Spc24; a component of the conserved kinetochore-associated Ndc80 complex involved in chromosome segregation, spindle checkpoint activity and kinetochore clustering; Hap43-induced gene ||	1	-0.60	-0.40	-0.13	0.30	-0.84	-1.15	-0.06	-0.48
641	|| orf19.4821 || LIP1 ||  || Secreted lipase, member of a lipase gene family whose members are expressed differentially in response to carbon source and during infection; may have a role in nutrition and/or in creating an acidic microenvironment ||	1	-1.76	-0.11	0.01	-0.24	-0.68	-1.37	-0.15	-0.86
642	|| orf19.764 ||  ||  || Ortholog(s) have clathrin-coated vesicle, cytoplasm localization ||	1	-3.57	0.04	-0.80	-0.25	-0.69	-3.46	-0.82	-0.25
643	|| orf19.2163 ||  ||  || Ortholog(s) have cytosol localization ||	1	-1.88	-0.97	-0.67	-0.61	-1.47	-1.89	-0.49	0.12
644	|| orf19.2163 ||  ||  || Ortholog(s) have cytosol localization ||	1	-1.65	-0.90	-0.89	-0.73	-1.51	-1.50	-0.16	-0.07
645	|| orf19.5527 ||  ||  || Protein with a predicted role in 5.8S rRNA processing; flow model biofilm induced ||	1	-0.80	-0.34	-0.02	-0.12	-0.65	-1.07	0.51	0.31
646	|| orf19.4055 ||  ||  || Protein similar to S. cerevisiae Ybr075wp; transposon mutation affects filamentous growth; clade-associated gene expression ||	1	-0.97	-0.26	-0.75	0.04	-1.75	-1.21	0.73	0.81
647	|| orf19.6307 ||  ||  || Ortholog of <i>C. dubliniensis CD36</i> : Cd36_30250, <i>Candida tenuis NRRL Y-1498</i> : CANTEDRAFT_98619, <i>Debaryomyces hansenii CBS767</i> : DEHA2G22594g and <i>Pichia stipitis Pignal</i> : PICST_50168 ||	1	-0.65	0.13	-1.13	0.27	-1.21	-0.84	-0.35	0.19
648	|| orf19.99 || HAL21 ||  || Putative phosphoadenosine-5'-phosphate or 3'-phosphoadenosine 5'-phosphosulfate phosphatase; possible role in sulfur recycling; ortholog of S. cerevisiae Met22; predicted Kex2 substrate; F-12/CO2 biofilm induced ||	1	-1.37	-1.27	-1.26	0.21	-2.29	-1.34	-1.51	-0.74
649	|| orf19.99 || HAL21 ||  || Putative phosphoadenosine-5'-phosphate or 3'-phosphoadenosine 5'-phosphosulfate phosphatase; possible role in sulfur recycling; ortholog of S. cerevisiae Met22; predicted Kex2 substrate; F-12/CO2 biofilm induced ||	1	-1.37	-1.27	-1.26	0.21	-2.29	-1.34	-1.51	-0.74
650	|| orf19.4349 ||  ||  || Protein of unknown function; transcript repressed by elevated CO2; Spider biofilm induced ||	1	-0.17	-0.55	-0.95	-0.17	-0.91	-0.68	-1.37	-0.37
651	|| orf19.4768 ||  ||  || Protein of unknown function; Spider biofilm induced ||	1	-0.06	-1.05	-0.13	0.88	-1.28	-0.90	-0.54	-0.39
652	|| orf19.670.2 ||  ||  || Protein of unknown function; hypoxia, Hap43-repressed; ketoconazole induced; induced in oralpharyngeal candidasis; 16h flow model biofilm repressed, late-stage flow model biofilm induced; rat catheter and Spider biofilm induced ||	1	-0.36	-1.39	-1.75	-1.28	-0.54	-1.00	0.55	-0.18
653	|| orf19.69 ||  ||  || Protein of unknown function; induced by Mnl1 under weak acid stress ||	1	-0.63	0.06	-0.45	-0.19	-0.88	0.37	-1.05	-0.89
654	|| orf19.6586 ||  ||  || Protein of unknown function; transcript induced by benomyl or in azole-resistant strain overexpressing MDR1; Ssn6 colony morphology-related regulation; induced by NO; Hap43-repressed; rat catheter and flow model biofilm induced ||	1	-0.11	0.73	-0.42	-0.65	0.05	0.40	-1.19	-1.33
655	|| orf19.6899 ||  ||  || Putative oxidoreductase; mutation confers hypersensitivity to toxic ergosterol analog; rat catheter and Spider biofilm induced ||	1	0.65	1.34	-0.67	-1.24	-0.43	-0.15	-1.59	-1.49
656	|| orf19.6899 ||  ||  || Putative oxidoreductase; mutation confers hypersensitivity to toxic ergosterol analog; rat catheter and Spider biofilm induced ||	1	-0.04	1.44	-1.49	-0.90	-0.63	-0.13	-2.59	-1.22
657	|| orf19.6416 ||  ||  || Protein involved in N-glycosylation; Spider biofilm induced; rat catheter biofilm repressed ||	1	0.05	0.21	-0.51	-0.36	-0.36	-0.03	-0.79	-0.84
658	|| orf19.4377 || KRE1 ||  || Cell wall glycoprotein; beta glucan synthesis; increases glucan content in S. cerevisiae kre1, complements killer toxin sensitivity; caspofungin induced; Spider/rat catheter/flow model biofilm induced; Bcr1-repressed in RPMI a/a biofilms ||	1	0.28	0.30	-0.56	-0.66	-0.02	0.06	-0.70	-1.02
659	|| orf19.4056 || BRG1 ||  || Transcription factor; recruits Hda1 to hypha-specific promoters; Tn mutation affects filamentation; Hap43-repressed; Spider and flow model biofilm induced; required for Spider biofilm formation; Bcr1-repressed in RPMI a/a biofilms ||	1	0.21	0.48	-1.16	-1.09	-0.25	-0.01	-0.83	-1.40
660	|| orf19.1360 ||  ||  || Ortholog(s) have role in mitochondrial genome maintenance and mitochondrion localization ||	1	-0.13	0.14	-1.16	-0.82	-0.36	0.19	-0.44	-1.09
661	|| orf19.1117 ||  ||  || Protein similar to Candida boidinii formate dehydrogenase; virulence-group-correlated expression; Hap43-repressed; Spider biofilm repressed ||	1	0.19	2.47	-4.10	-0.52	-0.37	1.09	-1.33	-4.14
662	|| orf19.1363 ||  ||  || Putative protein of unknown function; Plc1-regulated; transcript induced by Mnl1 under weak acid stress; flow model, rat catheter, Spider biofilm induced ||	1	-0.60	-0.30	-4.43	-1.45	-1.09	0.14	-0.76	-0.36
663	|| orf19.2442 ||  ||  || Ortholog of S. cerevisiae Shg1; a COMPASS (Set1C) complex subunit that methylates histone H3 on lysine 4 and is required in transcriptional silencing near telomeres; repressed in an azole-resistant strain overexpressing MDR1 ||	1	-1.14	-0.90	-1.89	-1.12	-0.91	-0.54	-1.04	-0.02
664	|| orf19.3758 ||  ||  || Ortholog(s) have fungal-type vacuole membrane localization ||	1	-1.48	-0.38	-2.85	-0.39	-0.63	-1.06	-1.64	-0.53
665	|| orf19.5399 || IFF11 ||  || Secreted protein required for normal cell wall structure and for virulence; member of the IFF family; Hap43p-repressed gene ||	1	-0.74	-0.28	-0.63	-0.92	-1.12	-0.72	-0.26	0.02
666	|| orf19.1159 ||  ||  || Protein similar to A. nidulans CysA serine O-trans-acetylase; suggests that C. albicans uses an O-acetyl-serine (OAS) pathway of sulfur assimilation; F-12/CO2 early biofilm induced; Spider biofilm induced ||	1	-0.33	-0.21	-0.81	-0.56	-0.75	-0.71	0.01	-0.18
667	|| orf19.2738 || SUL2 ||  || Putative sulfate transporter; transcript negatively regulated by Sfu1; amphotericin B induced; F-12/CO2 and Spider biofilm induced ||	1	-0.63	-0.64	-2.02	-1.65	-1.47	-1.09	-0.48	-0.56
668	|| orf19.6795 ||  ||  || Ortholog(s) have enzyme activator activity ||	1	-0.62	-0.39	-0.97	-0.48	-1.00	-0.89	-0.55	-0.60
669	|| orf19.3674 || GAL102 ||  || UDP-glucose 4,6-dehydratase; role in mannosylation of cell wall proteins; mutation confers hypersensitivity to toxic ergosterol analog; overlaps orf19.3673; Spider biofilm induced ||	1	-0.49	-0.87	-0.84	-1.37	0.14	-1.18	-0.36	-0.90
670	|| orf19.1969 || CCW14 ||  || Putative mannoprotein of cell wall with role in response to stress; increased mRNA abundance observed in cyr1 homozygous mutant (hyphal or yeast-form cells) and in ras1 homozygous mutant (yeast-form cells) ||	1	-0.30	-0.73	-1.32	-0.84	-0.24	-1.12	-0.18	-0.89
671	|| orf19.3974 || PUT2 ||  || Putative delta-1-pyrroline-5-carboxylate dehydrogenase; alkaline upregulated; protein present in exponential and stationary growth phase yeast cultures; flow model biofilm induced; Spider biofilm induced ||	1	0.29	-0.21	-0.84	-0.77	-0.07	-0.34	-0.32	-0.41
672	|| orf19.6073 || HMX1 ||  || Heme oxygenase; utilization of hemin iron; transcript induced by heat, low iron, or hemin; repressed by Efg1; induced by low iron; upregulated by Rim101 at pH 8; Hap43-induced; Spider and flow model biofilm induced ||	1	0.10	-0.36	-1.81	-1.14	-0.07	0.11	-1.37	-1.19
673	|| orf19.3481 ||  ||  || Putative mitochondrial ATP-dependent RNA helicase of the DEAD-box family, transcription is activated in the presence of elevated CO2 ||	1	-0.06	-0.60	-0.88	-0.57	-0.14	-0.12	-0.75	-0.64
674	|| orf19.1886 || RCL1 ||  || Putative U3-containing 90S preribosome processome complex subunit; Hap43-induced; essential; S. cerevisiae ortholog is essential; represses in core stress response; ||	1	-0.17	-0.59	-1.13	-0.51	-0.35	0.04	-0.68	-0.69
675	|| orf19.7084 || DFI1 ||  || Cell-surface associated glycoprotein; promotes activation of Cek1 in a matrix-dependent manner; N-glycosylated; Spider biofilm induced ||	1	-0.09	-0.27	-0.88	-0.74	-0.35	-0.01	-0.58	-0.32
676	|| orf19.4527 || HGT1 ||  || High-affinity MFS glucose transporter; induced by progesterone, chloramphenicol, benomyl; likely essential for growth; protein newly produced during adaptation to the serum; rat catheter and Spider biofilm induced ||	1	-0.13	-1.05	-2.18	-1.12	-0.72	-0.91	-0.40	-0.77
677	|| orf19.4076 || MET10 ||  || Sulfite reductase; role in sulfur amino acid metabolism; induced by human whole blood or PMNs; Hog1-induced; possibly adherence-induced; flow model, Spider model, F-12/CO2 biofilm induced ||	1	-0.23	-0.59	-1.00	-0.76	-0.48	-0.29	-0.42	-0.56
678	|| orf19.4211 || FET3 ||  || Multicopper oxidase; for growth in low iron, prostaglandin E2 synthesis; ketoconazole/caspofungin/amphotericin B repressed; Sef1/Sfu1/Hap43 regulated; reports differ if functional homolog of ScFet3; rat catheter and Spider biofilm induced ||	1	-0.21	-0.94	-1.74	-1.20	-0.58	-0.43	-0.76	-0.88
679	|| orf19.6000 || CDR1 ||  || Multidrug transporter of ABC superfamily; transports phospholipids in an in-to-out direction; induced by beta-estradiol, progesterone, corticosteroid, or cholesterol; Spider biofilm induced ||	1	-0.01	-0.60	-0.96	-0.76	-0.15	-0.25	-0.36	-0.27
680	|| orf19.6078 || POL93 ||  || Predicted ORF in retrotransposon Tca8 with similarity to the Pol region of retrotransposons encoding reverse transcriptase, protease and integrase; downregulated in response to ciclopirox olamine; F-12/CO2 early biofilm induced ||	1	-0.02	-0.88	-1.76	-1.24	-0.29	-0.29	-0.35	-0.48
681	|| orf19.7502 ||  ||  || Protein of unknown function; Hap43-induced gene; upregulated in a cyr1 null mutant; Spider biofilm induced ||	1	0.04	-0.51	-1.43	-0.91	-0.20	-0.28	-0.23	-0.56
682	|| orf19.6139 || FRE7 ||  || Copper-regulated cupric reductase; repressed by ciclopirox olamine or 17-beta-estradiol; induced by alkaline conditions or interaction with macrophage; Spider biofilm induced ||	1	0.14	-0.81	-2.16	-1.26	-0.28	-0.20	-0.88	-1.08
683	|| orf19.4933 || FAD3 ||  || Omega-3 fatty acid desaturase; production of alpha-linolenic acid, a major component of membranes; caspofungin induced; Plc1-regulated; colony morphology-related gene regulation by Ssn6; Spider biofilm induced, flow model biofilm repressed ||	1	0.20	-0.90	-1.60	-1.01	0.00	-0.01	-0.41	-0.79
684	|| orf19.7566 ||  ||  || Predicted amino acid transport domain; transcript upregulated in clinical strains from HIV+ patients with oral candidiasis; alkaline upregulated by Rim101; rat catheter, Spider and flow model biofilm induced ||	1	0.08	-0.42	-0.71	-0.67	-0.24	-0.10	-0.21	-0.48
685	|| orf19.715 ||  ||  || Protein of unknown function; Hap43-induced; rat catheter and Spider biofilm induced ||	1	-0.33	-1.04	-1.37	-1.43	-0.28	-0.61	-0.37	-0.97
686	|| orf19.2263 ||  ||  || Has domain(s) with predicted adenyl nucleotide binding activity ||	1	-0.20	-0.67	-0.74	-0.71	-0.19	-0.22	-0.15	-0.59
687	|| orf19.4743 || AFG1 ||  || Putative mitochondrial ATPase of the AAA family; similar but not orthologous to S. cerevisiae Afg1; mutant is viable; regulated by Sef1, Sfu1, and Hap43 ||	1	-0.34	-0.77	-0.94	-0.94	-0.75	-0.94	-0.20	-0.91
688	|| orf19.2461 || PRN4 ||  || Protein with similarity to pirins; induced by benomyl treatment; flow model biofilm repressed ||	1	-0.07	-0.60	-0.81	-0.87	-0.13	-0.74	-0.42	-0.83
689	|| orf19.6580 ||  ||  || Protein of unknown function; Spider biofilm induced ||	1	-0.18	-0.44	-0.69	-1.03	-0.02	-0.55	-0.41	-0.77
690	|| orf19.1048 || IFD6 ||  || Aldo-keto reductase; similar to aryl alcohol dehydrogenases; protein increase correlates with MDR1 overexpression (not CDR1 or CDR2) in fluconazole-resistant clinical isolates; farnesol regulated; possibly essential; Spider biofilm induced ||	1	-0.44	-0.43	-0.81	-1.24	-0.21	-0.83	-0.34	-0.74
691	|| orf19.4900 || MNN12 ||  || Predicted alpha-1,3-mannosyltransferase activity with a role in protein glycosylation ||	1	-0.30	-0.42	-0.92	-1.39	-0.47	-0.89	-0.68	-1.01
692	|| orf19.1150.1 ||  ||  || Ortholog of <i>C. dubliniensis CD36</i> : Cd36_10990, <i>C. parapsilosis CDC317</i> : CPAR2_804585, <i>Candida tenuis NRRL Y-1498</i> : cten_CGOB_00256 and <i>Debaryomyces hansenii CBS767</i> : DEHA2F10406g ||	1	-0.20	-0.22	-0.66	-1.06	-0.38	-0.52	-0.43	-0.90
693	|| orf19.1333 || SNG3 ||  || Putative membrane transporter; Hap43p-induced gene; mutation confers hypersensitivity to toxic ergosterol analog; shows colony morphology-related gene regulation by Ssn6p ||	1	-0.06	-0.25	-0.65	-0.82	-0.39	-0.89	-0.41	-0.86
694	|| orf19.5155 || CHS6 ||  || Protein with tetratricopeptide repeats (TPRs); ortholog of S. cerevisiae Chs6, which has role in localizing chitin synthase; Cyr1-regulated in hyphae; possibly essential, disruptants not obtained by UAU1 method; flow model biofilm repressed ||	1	-0.10	-0.55	-0.82	-1.16	-0.60	-1.14	-0.25	-1.48
695	|| orf19.4679 || AGP2 ||  || Amino acid permease; hyphal repressed; white-opaque switch regulated; induced in core caspofungin response, during cell wall regeneration, by flucytosine; regulated by Sef1, Sfu1, and Hap43; rat catheter and Spider biofilm induced ||	1	0.10	-0.37	-0.66	-0.71	-0.33	-0.52	-0.15	-0.68
696	|| orf19.2179 || SIT1 ||  || Transporter of ferrichrome siderophores, not ferrioxamine B; required for human epithelial cell invasion in vitro, not for mouse systemic infection; regulated by iron, Sfu1, Rfg1, Tup1, Hap43; rat catheter and Spider biofilm induced ||	1	0.01	-0.60	-1.22	-0.98	-0.69	-0.65	-0.40	-0.89
697	|| orf19.1415 || FRE10 ||  || Major cell-surface ferric reductase under low-iron conditions; 7 transmembrane regions and a secretion signal predicted; Tup1, Rim101, Ssn6, Hog1, caspofungin repressed; ciclopirox olamine induced; rat catheter biofilm induced ||	1	0.04	-0.77	-1.25	-1.48	-0.84	-1.29	-1.07	-1.35
698	|| orf19.7314 || CDG1 ||  || Putative cysteine dioxygenases; role in conversion of cysteine to sulfite; transcript regulated upon white-opaque switch; rat catheter, Spider and flow model biofilm induced ||	1	0.29	-0.75	-0.73	-1.08	-0.73	-0.90	-0.82	-1.12
699	|| orf19.6874 ||  ||  || Putative helix-loop-helix (HLH) transcription factor with a role in filamentous growth ||	1	0.06	-0.18	-0.76	-0.65	-0.32	-0.40	-0.54	-0.86
700	|| orf19.6595 || RTA4 ||  || Protein similar to S. cerevisiae Rsb1p, involved in fatty acid transport; transposon mutation affects filamentous growth; alkaline downregulated; caspofungin induced; possibly an essential gene; Hap43p-repressed ||	1	-0.13	-0.44	-1.93	-1.66	-1.04	-1.08	-1.02	-0.94
701	|| orf19.2022 ||  ||  || Predicted ORF from Assembly 19; merged with orf19.2021 in Assembly 20 ||	1	-0.38	-0.34	-1.02	-1.09	-0.61	-0.58	-0.65	-0.73
702	|| orf19.2021 || HGT8 ||  || High-affinity glucose transporter of the major facilitator superfamily; 20 members in the C. albicans glucose transporter family; 12 probable membrane-spanning segments; gene has intron; expressed in rich medium; flow model biofilm induced ||	1	-0.36	-0.33	-0.89	-0.95	-0.60	-0.48	-0.63	-0.58
703	|| orf19.6077 ||  ||  || Putative protein of unknown function; shows colony morphology-related gene regulation by Ssn6p ||	1	-0.35	-0.13	-0.81	-0.96	-0.77	-0.60	-0.64	-0.64
704	|| orf19.24 || RTA2 ||  || Flippase; sphingolipid long chain base release; mediates calcineurin-dependent resistance to azoles; stress-associate; Plc1, Ca2+, calcineurin-regulated; ketoconazole, caspofungin induced; Spider biofilm induced; flow biofilm repressed ||	1	-0.18	-0.01	-0.76	-0.90	-0.51	-0.45	-0.38	-0.50
705	|| orf19.6679 ||  ||  || Ortholog(s) have cytosol, nucleus localization ||	1	-0.09	-0.22	-0.66	-0.90	-0.37	-0.42	-0.35	-0.42
706	|| orf19.2619 || PHO113 ||  || Putative constitutive acid phosphatase; Rim101-repressed; DTT-extractable; N-glycosylated; possibly an essential gene, disruptants not obtained by UAU1 method ||	1	-0.24	-0.43	-0.77	-0.74	-0.26	-0.41	-0.45	-0.62
707	|| orf19.1313 || CDR3 ||  || Transporter of the Pdr/Cdr family of the ATP-binding cassette superfamily; transports phospholipids out-to-in; expressed in opaque-phase cells; induced by macrophage interaction; fluconazole-repressed; Spider biofilm induced ||	1	-0.14	-0.38	-0.64	-0.63	-0.24	-0.33	-0.32	-0.51
708	|| orf19.7077 ||  ||  || Putative ferric reductase; induced by Mac1 under copper starvation; Plc1-regulated; Rim101-repressed ||	1	-0.05	-1.16	-2.22	-1.98	-0.57	-0.79	-1.35	-1.85
709	|| orf19.6007 ||  ||  || Predicted fatty acid acyl transferase-related protein domain; repressed by prostaglandins ||	1	-0.20	-0.49	-0.89	-1.07	-0.42	-0.26	-0.61	-0.92
710	|| orf19.4666 ||  ||  || Protein of unknown function; hyphal-induced expression, regulated by Cyr1, Ras1, Efg1; Spider biofilm induced ||	1	-0.13	-0.30	-0.85	-1.00	-0.48	-0.32	-0.56	-0.65
711	|| orf19.6578 ||  ||  || Predicted membrane transporter; vesicular neurotransmitter (VNT) family, major facilitator superfamily (MFS); repressed in core caspofungin response; induced in oralpharyngeal candidasis; Spider biofilm induced ||	1	-0.12	-0.18	-1.14	-1.04	-0.28	-0.36	-0.52	-0.75
712	|| orf19.3869 ||  ||  || Protein of unknown function; regulated by Tsa1, Tsa1B in minimal media at 37 degrees C; shows colony morphology-related gene regulation by Ssn6; Spider biofilm induced ||	1	-0.07	-0.32	-1.25	-1.00	-0.36	-0.55	-0.73	-0.89
713	|| orf19.3089 ||  ||  || Predicted mitochondrial intermembrane space protein; predicted role in phospholipid metabolism; rat catheter and Spider biofilm induced ||	1	-0.04	-0.13	-0.88	-0.73	-0.29	-0.28	-0.77	-0.91
714	|| orf19.5843 || SRR1 ||  || Two-component system response regulator; involved in stress response; Plc1-regulated; upregulated in cyr1 null mutant; flow model biofilm induced; Spider biofilm induced ||	1	-0.46	-0.48	-1.78	-1.50	-0.53	-0.35	-1.30	-1.76
715	|| orf19.6784 || PGA32 ||  || Putative GPI-anchored adhesin-like protein; induced in high iron; Spider biofilm induced ||	1	-0.12	-0.18	-0.82	-0.87	-0.34	-0.23	-0.59	-0.76
716	|| orf19.6741 ||  ||  || Putative plasma membrane protein; predicted role in cell wall integrity; regulated by Nrg1, Tup1; induced during chlamydospore formation in both C. albicans and C. dubliniensis ||	1	-0.49	-0.29	-1.17	-1.51	-0.89	-0.69	-1.32	-1.03
717	|| orf19.5753 || HGT10 ||  || Glycerol permease involved in glycerol uptake; member of the major facilitator superfamily; induced by osmotic stress, at low glucose in rich media, during cell wall regeneration; 12 membrane spans; Hap43p-induced gene ||	1	-0.83	-0.88	-2.11	-2.04	-0.99	-0.82	-2.12	-1.70
718	|| orf19.5431 ||  ||  || Protein of unknown function; Hap43-repressed; Spider biofilm induced ||	1	-0.61	-0.51	-1.72	-1.65	-0.87	-0.52	-1.50	-1.17
719	|| orf19.22 ||  ||  || Protein with homology to peroxisomal membrane proteins; Sef1p-, Sfu1p-, and Hap43p-regulated gene ||	1	-0.34	-0.47	-1.45	-1.57	-0.68	-0.53	-1.30	-1.24
720	|| orf19.207 || PGA55 ||  || GPI-anchored adhesin-like protein; filament induced; regulated by Nrg1, Tup1; regulated upon hyphal formation; mRNA binds to She3 and is localized to yeast-form buds and hyphal tips; induced during chlamydospore formation ||	1	-0.23	-0.45	-1.01	-1.07	-0.75	-0.41	-1.07	-0.91
721	|| orf19.4853 || HCM1 ||  || Protein with forkhead domain; similar to S. cerevisiae Hcm1p; Hap43p-induced gene ||	1	-0.29	-0.35	-0.87	-0.78	-0.62	-0.34	-0.75	-0.77
722	|| orf19.3270 ||  ||  || Predicted ORF from Assembly 19; merged with orf19.3269 in Assembly 20 ||	1	-0.14	-0.17	-0.70	-0.65	-0.47	-0.35	-0.59	-0.65
723	|| orf19.3664 || HSP31 ||  || Putative 30 kda heat shock protein; repressed during the mating process; rat catheter biofilm induced ||	1	-0.58	-0.47	-2.09	-1.96	-1.17	-0.94	-1.53	-2.10
724	|| orf19.768 || SYG1 ||  || Ortholog(s) have role in signal transduction and Golgi apparatus, endoplasmic reticulum, mitochondrion, plasma membrane localization ||	1	-0.28	-0.22	-1.01	-0.69	-0.41	-0.45	-0.57	-0.73
725	|| orf19.4456 || GAP4 ||  || Putative amino acid permease; hyphal induced; regulated by Hap43, Gcn2 and Gcn4; colony morphology-related gene regulation by Ssnp; detected at plasma membrane of yeast and germ tube by mass spec; Spider biofilm induced ||	1	-0.13	-0.28	-0.80	-0.69	-0.36	-0.15	-0.55	-0.46
726	|| orf19.409 ||  ||  || Ortholog of S. cerevisiae Aim38/Rcf2, cytochrome c oxidase subunit; plasma membrane localized; Hap43-repressed; induced in oralpharyngeal candidasis; flow model biofilm induced; Spider biofilm repressed ||	1	-0.25	-0.32	-0.85	-0.65	-0.25	-0.18	-0.68	-0.50
727	|| orf19.3475 ||  ||  || Described as a Gag-related protein; hyphal induced; downregulation correlates with clinical development of fluconazole resistance; repressed by nitric oxide, 17-beta-estradiol, ethynyl estradiol ||	1	-0.43	-0.39	-1.20	-0.89	-0.58	-0.36	-0.74	-0.53
728	|| orf19.7637 || YHB4 ||  || Protein related to flavohemoglobins; not required for wild-type nitric oxide resistance; has predicted globin, FAD-binding, and NAD(P)-binding domains but lacks some conserved residues of flavohemoglobins; Hap43p-repressed gene ||	1	-0.45	-0.26	-0.83	-0.69	-0.36	-0.41	-0.54	-0.42
729	|| orf19.5626 ||  ||  || Protein of unknown function; Plc1-regulated; induced by Mnl1 under weak acid stress; flow model biofilm induced ||	1	-0.35	-0.31	-1.20	-0.95	-0.10	-0.27	-0.73	-0.83
730	|| orf19.28 ||  ||  || Putative thiamine transmembrane transporter; Spider biofilm induced ||	1	-0.25	-0.43	-1.06	-0.72	-0.06	-0.20	-0.74	-0.83
731	|| orf19.716 ||  ||  || Protein of unknown function; Hap43-induced; regulated by Nrg1, Tup1; repressed by alpha pheromone in SpiderM medium; Spider biofilm induced; Bcr1-repressed in RPMI a/a biofilms ||	1	-1.43	-0.97	-1.21	-1.27	-0.84	-0.72	-1.30	-1.28
732	|| orf19.4873 ||  ||  || Protein of unknown function; transcript regulated by white-opaque switch; flow model biofilm induced; Spider biofilm induced ||	1	-1.20	-0.89	-0.79	-1.10	-0.66	-0.82	-0.75	-0.83
733	|| orf19.3621 ||  ||  || Possible pseudogene; similar to Ywp1p; ORF extended upstream from the initiating Met of orf19.3621 has a stop codon in the region corresponding to the Ywp1p signal peptide; disruption causes no apparent phenotype; no expression detected ||	1	-1.52	-1.08	-1.52	-1.84	-0.83	-1.48	-1.03	-0.93
734	|| orf19.756 || SAP7 ||  || Pepstatin A-insensitive secreted aspartyl protease; self-processing; expressed in human oral infection; Ssn6p-regulated; role in murine intravenous infection; induced during, but not required for, murine vaginal infection; N-glycosylated ||	1	-1.24	-1.39	-1.98	-2.39	-1.24	-1.39	-1.66	-1.46
735	|| orf19.2246 ||  ||  || Ortholog(s) have cytosol, nucleus localization ||	1	-0.31	-0.59	-0.73	-0.92	-0.31	-0.40	-0.45	-0.49
736	|| orf19.1264 || CFL2 ||  || Oxidoreductase; iron utilization; Sfu1/Sef1/Hap43/Nrg1/Tup1/Rim101 regulated; alkaline/low iron/fluphenazine/ciclopirox olamine, flucytosine, fluconazole, Spider/flow model/rat catheter biofilm induced; caspofungin/amphotericin B repressed ||	1	-0.61	-1.61	-1.57	-2.09	-1.08	-1.21	-0.95	-1.25
737	|| orf19.111 || CAN2 ||  || Basic amino acid permease; arginine metabolism; regulated by Nrg1/Tup1; caspofungin, flucytosine induced; colony morphology-related regulation by Ssn6; Hap43-repressed; rat catheter and Spider biofilm induced; promoter bound by Efg1 ||	1	-0.28	-0.33	-0.65	-0.70	-0.85	-0.42	-0.61	-0.44
738	|| orf19.2475 || PGA26 ||  || GPI-anchored adhesin-like protein of the cell wall; role in cell wall integrity; required for normal virulence; induced in high iron and during cell wall regeneration; Hap43-repressed ||	1	-0.70	-0.40	-1.15	-0.88	-1.10	-0.53	-0.78	-0.57
739	|| orf19.4769 || IPT1 ||  || Inositol phosphoryl transferase; catalyzes the synthesis of the most abundant sphingolipid, mannose-(inositol-P)2-ceramide, M(IP)2C, from MIPC; required for wild-type membrane localization of Cdr1; Spider biofilm induced ||	1	-0.29	-0.39	-0.88	-0.63	-0.67	-0.29	-0.58	-0.65
740	|| orf19.7586 || CHT3 ||  || Major chitinase; secreted; functional homolog of S. cerevisiae Cts1p; 4 N-glycosylation motifs; possible O-mannosylation; putative signal peptide; hyphal-repressed; farnesol upregulated in biofilm; regulated by Efg1p, Cyr1p, Ras1p ||	1	-0.55	-0.28	-0.84	-0.58	-0.69	-0.52	-0.65	-0.75
741	|| orf19.2824 ||  ||  || Predicted ORF from Assembly 19; merged with orf19.2823 in Assembly 20 ||	1	-0.35	-0.09	-0.56	-0.50	-0.30	-0.44	-0.68	-0.70
742	|| orf19.4774 || AOX1 ||  || Alternative oxidase; low abundance; constitutively expressed; one of two isoforms (Aox1p and Aox2p); involved in a cyanide-resistant respiratory pathway present in plants, protists, and some fungi, absent in S. cerevisiae; Hap43p-repressed ||	1	-1.06	-0.25	-1.45	-1.79	-1.28	-1.31	-1.61	-1.66
743	|| orf19.6245 ||  ||  || Protein of unknown function; regulated by osmotic stress via Hog1 and oxidative stress (Hog1- and Cap1-independent); induced by alpha pheromone in SpiderM medium; Spider biofilm induced ||	1	-0.64	-0.06	-0.73	-0.75	-0.44	-0.43	-0.77	-0.67
744	|| orf19.3110 ||  ||  || Possible mannosyltransferase; Spider biofilm induced ||	1	-0.68	-0.28	-0.74	-0.91	-0.64	-0.51	-1.07	-0.70
745	|| orf19.94 ||  ||  || Protein of unknown function; Spider biofilm induced ||	1	-0.90	-0.43	-1.34	-1.21	-1.08	-1.01	-1.36	-0.74
746	|| orf19.6817 || FCR1 ||  || Transcription factor; repressor of fluconazole/ketoconazole/brefeldin A resistance; Tn mutation enhances filamentation; partially rescues S. cerevisiae pdr1 pdr3 fluconazole sensitivity; rat catheter biofilm induced/Spider biofilm repressed ||	1	-0.49	-0.23	-0.63	-0.68	-0.74	-0.54	-0.56	-0.52
747	|| orf19.1368 ||  ||  || Protein of unknown function; flow model biofilm induced; Spider biofilm induced ||	1	-0.93	-0.28	-0.81	-1.30	-1.12	-1.00	-0.98	-0.86
748	|| orf19.3071 || MIH1 ||  || Putative protein phosphatase of the PTP family (tyrosine-specific); ortholog of S. cerevisiae Mih1; mRNA binds She3 ||	1	-0.60	-0.15	-0.45	-0.72	-0.72	-0.81	-0.71	-0.39
749	|| orf19.2531 || CSP37 ||  || Hyphal cell wall protein; role in progression of mouse systemic infection; predicted P-loop, divalent cation binding, N-glycosylation sites; expressed in yeast and hyphae; hyphal downregulated; stationary-phase enriched; GlcNAc-induced ||	1	-0.71	-0.10	-0.59	-0.82	-0.57	-0.93	-0.66	-0.79
750	|| orf19.7085 ||  ||  || Protein of unknown function; induced in core stress response; induced by cadmium stress via Hog1; oxidative stress-induced via Cap1; induced by Mnl1 under weak acid stress; macrophage-repressed; rat catheter and Spider biofilm induced ||	1	-0.72	-0.06	-0.87	-1.28	-0.26	-0.75	-0.96	-1.01
751	|| orf19.3048 ||  ||  || Protein of unknown function; repressed by alpha pheromone in SpiderM medium ||	1	-0.64	-0.29	-0.78	-1.13	-0.25	-1.07	-0.80	-1.11
752	|| orf19.3335 ||  ||  || Plasma membrane protein of unknown function; colony morphology-related gene regulation by Ssn6; repressed by nitric oxide ||	1	-0.49	-0.41	-0.80	-0.72	-0.17	-0.47	-0.76	-0.98
753	|| orf19.2726 ||  ||  || Putative plasma membrane protein; Plc1-regulated; Spider biofilm induced ||	1	-0.37	0.32	-0.78	-1.03	-0.46	-0.12	-0.85	-0.68
754	|| orf19.638 || FDH1 ||  || Formate dehydrogenase; oxidizes formate to CO2; Mig1 regulated; induced by macrophages; fluconazole-repressed; repressed by Efg1 in yeast, not hyphal conditions; stationary phase enriched; rat catheter and Spider biofilm induced ||	1	-0.41	0.48	-0.77	-1.20	-0.47	-0.42	-1.07	-0.97
755	|| orf19.6660 ||  ||  || Protein of unknown function; mRNA binds to She3; Hap43-repressed; rat catheter and flow model biofilm induced ||	1	-0.71	0.30	-1.01	-1.54	-0.60	-0.63	-1.58	-1.30
756	|| orf19.2724 ||  ||  || Protein of unknown function; flow model, rat catheter and Spider biofilm induced; Hap43-repressed ||	1	-0.68	0.35	-1.29	-1.52	-0.74	-0.50	-1.86	-1.53
757	|| orf19.4869 || SFU1 ||  || GATA-type transcription factor; regulator of iron-responsive genes; represses iron utilization genes if iron is present; Hap43-repressed; promotes gastrointestinal commensalism in mice; Spider biofilm induced ||	1	0.18	0.18	-0.38	-0.79	-0.10	-0.10	-0.83	-0.68
758	|| orf19.6514 || CUP9 ||  || Transcription factor; upregulated in clinical strains from HIV patients with oral candidiasis; yeast-hypha switch repressed; ketoconazole-induced; Plc1-regulated; colony morphology-related Ssn6 regulation; Spider, flow model biofilm induced ||	1	0.05	0.14	-0.78	-1.02	-0.10	-0.11	-0.80	-1.01
759	|| orf19.7372 || MRR1 ||  || Putative Zn(II)2Cys6 transcription factor; regulator of MDR1 transcription; gain-of-function mutations cause upregulation of MDR1 (a plasma membrane multidrug efflux pump) and multidrug resistance; Hap43-induced ||	1	0.07	-0.05	-0.61	-0.82	0.07	-0.16	-0.75	-0.86
760	|| orf19.5326 ||  ||  || Putative transcription factor with zinc finger DNA-binding motif; possible ortholog of S. cerevisiae Mig2p ||	1	0.35	-0.03	-0.56	-0.65	-0.02	-0.22	-0.69	-0.73
761	|| orf19.5919 || MEA1 ||  || Protein similar to <i>A. nidulans</i> MesA, which is involved in localization of actin cables; Hap43p-induced gene ||	1	0.08	-0.04	-0.43	-0.70	-0.15	-0.35	-0.73	-0.70
762	|| orf19.6976 ||  ||  || Predicted MFS membrane transporter; member of the proton coupled folate transporter/heme carrier protein family; virulence-group-correlated expression; Spider biofilm induced ||	1	-0.09	-0.01	-0.25	-0.53	-0.22	-0.25	-0.62	-0.75
763	|| orf19.5986 || THI4 ||  || Thiamine biosynthetic enzyme precursor; repressed during the mating process; stationary phase enriched protein; Spider biofilm induced ||	1	-0.13	-0.02	-0.73	-0.87	-0.58	-0.21	-0.86	-0.61
764	|| orf19.341 ||  ||  || Putative spermidine export pump; fungal-specific (no human or murine homolog) ||	1	-0.01	-0.02	-2.01	-2.72	-0.70	-0.53	-2.39	-1.93
765	|| orf19.6948 || CCC1 ||  || Manganese transporter; required for normal filamentous growth; mRNA binds She3, localized to hyphal tips; repressed by NO, alkaline pH; colony morphology-related regulation by Ssn6; regulated by Sef1, Sfu1, Hap43; Spider biofilm induced ||	1	-0.27	-0.18	-1.27	-1.39	-0.44	-0.17	-1.52	-1.34
766	|| orf19.1774 ||  ||  || Predicted dehydrogenase; transcript upregulated in an RHE model of oral candidiasis; virulence-group-correlated expression; Spider biofilm repressed ||	1	-0.01	-0.01	-1.93	-1.54	-0.88	-0.13	-1.62	-1.65
767	|| orf19.6691 ||  ||  || Putative ember of the multi-drug and toxin extrusion (MATE) family of the multidrug/oligosaccharidyl-lipid/polysaccharide exporter superfamily; Spider biofilm induced ||	1	-0.14	-0.28	-0.87	-1.38	-0.41	-0.14	-0.78	-0.72
768	|| orf19.4889 ||  ||  || Predicted MFS family membrane transporter, member of the drug:proton antiporter (12 spanner) (DHA1) family; Spider biofilm induced ||	1	-0.02	-0.51	-0.82	-1.36	-0.19	-0.25	-0.78	-0.82
769	|| orf19.5908 || TEC1 ||  || TEA/ATTS transcription factor; white cell pheromone response, hyphal gene regulation; required for Spider and RPMI biofilm formation; regulates BCR1; Cph2 regulated transcript; alkaline, rat catheter, Spider, flow model biofilm induced ||	1	-0.04	-0.09	-0.60	-1.48	-0.17	-0.40	-0.87	-0.82
770	|| orf19.254 ||  ||  || Protein of unknown function; Hog1p-repressed; Spider biofilm induced ||	1	0.04	-0.11	-0.89	-1.00	0.08	-0.33	-0.53	-0.69
771	|| orf19.3448 ||  ||  || Protein of unknown function; ketoconazole-repressed ||	1	-0.21	-0.07	-2.43	-2.27	-0.11	-0.89	-1.47	-1.54
772	|| orf19.4282 || IFH1 ||  || Transcription factor; forms a heterodimer with Fhl11 that is tethered to promoters by Tbf1; positively regulates rRNA and ribosomal protein gene transcription; Spider biofilm induced ||	1	0.37	-0.21	-0.89	-0.84	-0.40	-0.21	-0.65	-0.71
773	|| orf19.5017 || DUR32 ||  || Putative urea transporter; possibly an essential gene, disruptants not obtained by UAU1 method ||	1	-0.36	-0.04	-0.97	-0.86	-0.71	-0.39	-1.28	-0.43
774	|| orf19.5805 || DLD1 ||  || Putative D-lactate dehydrogenase; white cell-specific trancript; colony morphology-related gene regulation by Ssn6; Hap43-repressed; rat catheter biofilm induced; Spider biofilm repressed ||	1	-0.41	-0.03	-0.80	-0.86	-0.74	-0.31	-1.06	-0.45
775	|| orf19.2959.1 ||  ||  || Gene induced by hypoxia and ketoconazole; oral infection upregulated; mutants have reduced capacity to damage oral epithelial cells; Spider biofilm induced ||	1	-0.74	-0.10	-0.93	-0.76	-0.65	-0.26	-0.69	-0.24
776	|| orf19.6770 ||  ||  || protein with ENTH Epsin domain, N-terminal; Spider biofilm repressed ||	1	-0.53	-0.13	-0.81	-0.63	-0.63	-0.19	-0.81	-0.48
777	|| orf19.4959 ||  ||  || Protein of unknown function; Spider biofilm repressed ||	1	-0.94	-0.11	-1.41	-0.82	-1.10	-0.08	-1.07	-0.71
778	|| orf19.1585 || ZRT2 ||  || Zinc transporter; ciclopirox olamine, fluconazole, alkaline repressed; transcript induced by amphotericin B, interaction with macrophages; possibly essential (UAU1 method); induced in oralpharyngeal candidiasis; Spider biofilm induced ||	1	-0.47	-0.31	-1.06	-0.77	-0.66	0.02	-0.78	-0.32
779	|| orf19.5305 || RHD3 ||  || GPI-anchored yeast-associated cell wall protein; induced in high iron; clade-associated gene expression; not essential for cell wall integrity; fluconazole-repressed; flow model and Spider biofilm repressed ||	1	-0.34	-0.11	-1.49	-0.97	-0.57	-0.27	-0.67	-0.40
780	|| orf19.3439 ||  ||  || Protein of unknown function; Cyr1-repressed; rat catheter and Spider biofilm induced ||	1	-0.67	0.07	-3.35	-2.04	-0.91	-1.08	-1.23	-1.03
781	|| orf19.2600 || SPC98 ||  || Putative component of the microtubule-nucleating Tub4p (gamma-tubulin) complex; periodic mRNA expression, peak at cell-cycle S/G2 phase ||	1	-0.12	-0.09	-1.25	-0.75	0.26	-0.54	-0.35	-0.74
782	|| orf19.3988 ||  ||  || Putative adhesin-like protein; induced by Mnl1 under weak acid stress; rat catheter and Spider biofilm induced ||	1	-0.14	0.16	-1.21	-0.47	0.14	-0.67	-1.08	-0.73
783	|| orf19.4890 || CLA4 ||  || Ste20p family Ser/Thr kinase required for wild-type filamentous growth, organ colonization and virulence in mouse systemic infection; role in chlamydospore formation; functional homolog of S. cerevisiae Cla4p; mutant caspofungin sensitive ||	1	-0.60	-0.37	-1.01	-0.33	-0.41	-0.64	-1.13	-1.29
784	|| orf19.7311 ||  ||  || Protein of unknown function; Spider biofilm induced ||	1	-0.73	0.06	-0.49	-0.40	-0.76	-0.63	-0.83	-0.82
785	|| orf19.7311 ||  ||  || Protein of unknown function; Spider biofilm induced ||	1	-0.73	0.06	-0.49	-0.40	-0.76	-0.63	-0.83	-0.82
786	|| orf19.5859 || DAL8 ||  || Putative allantoate permease; fungal-specific (no human or murine homolog) ||	1	-0.46	-0.38	-0.72	-0.72	-1.10	-0.98	-1.09	-1.40
787	|| orf19.5315 || FGR6 ||  || Protein lacking an ortholog in S. cerevisiae; transposon mutation affects filamentous growth; removed from Assembly 20 ||	1	-0.39	-0.08	-0.33	-0.70	-0.52	-1.06	-0.70	-0.92
788	|| orf19.5826 ||  ||  || Predicted amino acid transmembrane transporter; rat catheter biofilm repressed ||	1	-0.97	-0.26	-0.65	-0.48	-0.78	-1.48	-0.87	-1.21
789	|| orf19.1600 ||  ||  || Ortholog of <i>C. dubliniensis CD36</i> : Cd36_23530, <i>C. parapsilosis CDC317</i> : CPAR2_406140, <i>Candida tenuis NRRL Y-1498</i> : CANTEDRAFT_116829 and <i>Debaryomyces hansenii CBS767</i> : DEHA2B01826g ||	1	-0.47	-0.22	-0.20	-0.92	-0.90	-0.78	-0.63	-0.42
790	|| orf19.5449 ||  ||  || Predicted integral membrane protein; Spider biofilm induced ||	1	-0.32	-0.05	-0.35	-0.69	-0.77	-0.82	-0.48	-0.61
791	|| orf19.2681 || RBT7 ||  || Protein with similarity to RNase T2 enzymes; has putative secretion signal; expression is Tup1-repressed ||	1	-0.58	0.28	-0.41	-1.18	-1.38	-1.50	-0.94	-0.48
792	|| orf19.1258 ||  ||  || Adhesin-like protein; regulated by Tsa1, Tsa1B in minimal media at 37 deg; clade-associated gene expression; induced by alpha pheromone in SpiderM medium; Hap43-induced; Spider biofilm repressed ||	1	-0.91	0.51	-0.01	-0.75	-1.16	-0.99	-0.85	-0.42
793	|| orf19.3839 || SAP10 ||  || Secreted aspartyl protease; roles in adhesion, virulence (RHE model), cell surface integrity; distinct specificity from Sap9; at cell membrane and wall; GPI-anchored; induced in low iron; Tbf1-activated; Spider biofilm induced ||	1	-1.04	0.38	-0.38	-1.01	-1.15	-0.92	-0.77	-0.44
794	|| orf19.1887 ||  ||  || Ortholog(s) have sterol esterase activity, role in sterol metabolic process and integral to membrane, lipid particle localization ||	1	-0.77	0.07	-0.12	-0.60	-0.85	-0.65	-0.68	-0.36
795	|| orf19.2737 ||  ||  || Carbohydrate kinase domain-containing protein; Spider biofilm induced ||	1	-0.96	0.25	-0.34	-0.56	-0.96	-0.66	-0.87	-0.38
796	|| orf19.2030 ||  ||  || Plasma membrane-associated protein; induced in cyr1 or ras1 mutant; induced by hypoxia, ketoconazole and during growth in the mouse cecum; induced in oralpharyngeal candidasis; Spider biofilm induced ||	1	-0.58	0.24	-0.32	-0.42	-0.85	-0.63	-0.39	-0.37
797	|| orf19.6489 || FMP45 ||  || Predicted membrane protein induced during mating; mutation confers hypersensitivity to toxic ergosterol analog, to amphotericin B; alkaline repressed; repressed by alpha pheromone in SpiderM medium; rat catheter, Spider biofilm induced ||	1	-1.24	0.78	-0.89	-1.16	-2.49	-1.83	-1.59	-0.91
798	|| orf19.675 ||  ||  || Cell wall protein; induced in core stress response and core caspofungin response; iron-regulated; amphotericin B, ketoconazole, and hypoxia induced; regulated by Cyr1, Ssn6; induced in oralpharyngeal candidasis; Spider biofilm repressed ||	1	-1.14	0.56	-0.86	-0.67	-1.40	-0.67	-1.20	-0.49
799	|| orf19.3932 ||  ||  || Predicted RNA binding protein; stationary phase enriched; induced in core caspofungin response; induced by nitric oxide independent of Yhb1; repressed in ssr1 null; ketoconazole, hypoxia induced; Spider biofilm induced ||	1	-1.27	0.78	-0.86	-0.85	-1.19	-0.89	-1.36	-0.77
800	|| orf19.822 || HSP21 ||  || Small heat shock protein; role in stress response and virulence; fluconazole-downregulated; induced in cyr1 or ras1 mutant; stationary phase enriched protein; detected in some, not all, biofilm extracts; Spider biofilm induced ||	1	-1.66	0.48	-1.69	-1.73	-1.28	-0.88	-1.86	-1.16
801	|| orf19.2896 || SOU1 ||  || Enzyme involved in utilization of L-sorbose; has sorbitol dehydrogenase, fructose reductase, and sorbose reductase activities; NAD-binding site motif; transcriptional regulation affected by chromosome 5 copy number; Hap43p-induced gene ||	1	-1.03	0.40	-0.92	-1.22	-1.16	-0.81	-1.08	-0.67
802	|| orf19.7310 ||  ||  || Protein with a role in directing meiotic recombination events to homologous chromatids; induced by ciclopirox olamine; positively regulated by Sfu1; Hog1, fluconazole-repressed; Hap43-induced; Spider biofilm induced ||	1	-1.27	0.54	-0.83	-1.73	-1.45	-1.12	-1.15	-1.16
803	|| orf19.7284 || ASR2 ||  || Adenylyl cyclase and stress responsive protein; induced in cyr1 or ras1 mutant; stationary phase enriched protein; Spider biofilm induced ||	1	-1.42	0.30	-0.82	-1.51	-1.22	-0.77	-1.33	-1.18
804	|| orf19.3160 || HSP12 ||  || Heat-shock protein; induced by osmotic/oxidative/cadmium stress, fluphenazine treatment, low iron, CDR1 and CDR2 overexpression, or ssn6 or ssk1 null mutation; overexpression increases resistance to farnesol and azoles ||	1	-0.84	0.23	-0.64	-1.32	-0.83	-0.45	-0.98	-0.74
805	|| orf19.251 || GLX3 ||  || Glutathione-independent glyoxalase; binds human immunoglobulin E; alkaline, fluconazole, Hog1 repressed; hypoxia, oxidative stress via Cap1, Hap43 induced; stationary-phase enriched; rat catheter, Spider biofilm induced ||	1	-0.71	0.44	-0.30	-1.19	-0.87	-0.65	-0.83	-0.78
806	|| orf19.3369 || MOH1 ||  || Ortholog of S. cerevisiae Moh1, essential for staionary phase growth; induced by alpha pheromone in SpiderM medium and by Mnl1 under weak acid stress; possibly essential (UAU1 method); flow model biofilm induced; Spider biofilm induced ||	1	-1.22	1.08	-0.38	-1.82	-1.19	-1.23	-1.33	-1.18
807	|| orf19.2846 ||  ||  || Protein of unknown function; Hap43-repressed; induced in core caspofungin response; regulated by yeast-hypha switch; Spider biofilm repressed ||	1	-1.03	0.93	-0.92	-1.56	-1.06	-1.12	-1.03	-0.80
808	|| orf19.750 ||  ||  || Protein of unknown function; exogenously expressed protein is a substrate for Kex2p processing in vitro ||	1	-0.46	0.48	-0.79	-0.50	-0.49	-0.64	-0.81	-0.68
809	|| orf19.4526 || HSP30 ||  || Putative heat shock protein; fluconazole repressed; amphotericin B induced; Spider biofilm induced; rat catheter biofilm induced ||	1	-0.83	1.23	-1.82	-1.34	-1.17	-1.30	-1.06	-0.59
810	|| orf19.5673 || OPT7 ||  || Putative oligopeptide transporter; possibly transports GSH or related compounds; Hog1-induced; expression of OPT6, -7, or -8 does not suppress defect of mutant lacking OPT1-3; Hap43-repressed; F-12/CO2 early biofilm induced ||	1	-0.57	0.44	-1.47	-1.34	-1.56	-0.77	-0.62	-0.55
811	|| orf19.5673 || OPT7 ||  || Putative oligopeptide transporter; possibly transports GSH or related compounds; Hog1-induced; expression of OPT6, -7, or -8 does not suppress defect of mutant lacking OPT1-3; Hap43-repressed; F-12/CO2 early biofilm induced ||	1	-0.57	0.44	-1.47	-1.34	-1.56	-0.77	-0.62	-0.55
812	|| orf19.5615 || AYR2 ||  || Putative NADPH-dependent 1-acyl dihydroxyacetone phosphate reductase; shows colony morphology-related gene regulation by Ssn6p ||	1	-0.49	0.17	-0.65	-0.67	-0.79	-0.59	-0.53	-0.22
813	|| orf19.348 || SKN2 ||  || Protein with a potential role in beta-1,6 glucan biosynthesis; similarity to Kre6 and Skn1; possibly essential, disruptants not obtained by UAU1 method; Hap43-induced; flow model biofilm induced; rat catheter biofilm repressed ||	1	-0.54	0.18	-0.64	-0.59	-0.91	-0.67	-0.26	-0.03
814	|| orf19.6001 || SAP3 ||  || Secreted aspartyl proteinase, acts in utilization of protein as nitrogen source; assessment of virulence role complicated by URA3 effects; regulated by growth phase; produced by opaque phase cells; alpha-pheromone repressed ||	1	-0.80	0.44	-0.69	-0.73	-0.92	-0.64	-0.84	0.11
815	|| orf19.3107 ||  ||  || Ortholog of <i>C. dubliniensis CD36</i> : Cd36_46490, <i>Pichia stipitis Pignal</i> : PICST_33598, <i>Spathaspora passalidarum NRRL Y-27907</i> : spas_CGOB_00037 and <i>Candida tropicalis MYA-3404</i> : CTRG_03758 ||	1	-2.08	-0.13	-0.83	-4.39	-1.28	-1.12	-3.80	-1.44
816	|| orf19.1368 ||  ||  || Protein of unknown function; flow model biofilm induced; Spider biofilm induced ||	1	-0.58	-0.03	-0.43	-1.25	-0.75	-0.81	-0.68	-0.75
817	|| orf19.5070 ||  ||  || Similar to cell-wall mannoproteins; induced in low iron; induced in cyr1 homozygous null; regulated by osmotic and oxidative stress via Hog1; Spider biofilm induced ||	1	-0.34	0.23	-0.50	-1.56	-0.51	-0.80	-0.87	-0.87
818	|| orf19.2870 ||  ||  || Protein of unknown function; rat catheter and Spider biofilm induced ||	1	-0.47	0.39	-0.70	-1.41	-0.51	-1.22	-0.51	-1.14
819	|| orf19.842 || ASR3 ||  || Adenylyl cyclase and stress responsive protein; induced in cyr1 or ras1 mutant; Spider biofilm induced ||	1	-0.34	0.24	-0.39	-0.91	-0.32	-0.95	-0.63	-1.08
820	|| orf19.2882 || XUT1 ||  || Putative high-affinity, high-capacity xanthine-uric acid/H+ symporter; similar to A. nidulans UapA; member of the Nucleobase-Ascorbate Transporter/Nucleobase-Cation Symporter (NAT/NCS2) family; rat catheter biofilm induced ||	1	-0.18	0.10	-0.04	-1.20	-0.14	-0.89	-0.87	-0.97
821	|| orf19.5775 ||  ||  || Predicted ORF overlapping the Major Repeat Sequence on chromosome 6; member of a family encoded by FGR6-related genes in the RB2 repeat sequence; rat catheter biofilm repressed ||	1	-0.25	-0.09	0.25	-1.44	-0.05	-0.95	-0.77	-0.64
822	|| orf19.6277 ||  ||  || Has domain(s) with predicted phosphatidylinositol binding activity and role in cell communication ||	1	0.05	0.71	-0.41	-1.93	-0.14	-1.07	-1.76	-1.39
823	|| orf19.5612 || BMT4 ||  || Beta-mannosyltransferase; for elongation of beta-mannose chains on the acid-labile fraction of cell wall phosphopeptidomannan; 9-gene family member; regulated by Tsa1, Tsa1B; flow model biofilm induced; rat catheter biofilm repressed ||	1	-0.28	0.47	0.03	-1.16	-0.43	-0.62	-0.76	-0.76
824	|| orf19.655 || PHO84 ||  || High-affinity phosphate transporter; transcript regulated by white-opaque switch; Hog1, ciclopirox olamine or alkaline induced; caspofungin, stress repressed; upregulated in RHE model; Spider and flow model biofilm induced, Hap43-induced ||	1	-0.31	0.28	-0.23	-0.66	-0.36	-0.21	-0.67	-0.65
825	|| orf19.1979 || GIT3 ||  || Glycerophosphocholine permease; white cell specific transcript; fungal-specific; alkaline repressed; caspofungin, macrophage/pseudohyphal-repressed; flow model biofilm induced; Spider biofilm induced ||	1	-0.27	0.43	-0.12	-0.52	-0.39	-0.38	-0.72	-0.71
826	|| orf19.2356 || CRZ2 ||  || C2H2 transcription factor; crz1 not crz2 null mutation suppresses fluconazole resistance of homozygous cka2 null; Rim101-repressed at pH 8; required for yeast cell adherence to silicone substrate; Spider biofilm induced ||	1	-0.34	0.91	0.04	-1.14	-0.29	-0.52	-1.80	-1.29
827	|| orf19.4266 || SPR28 ||  || Septin; similar to S. cerevisiae meiotic/sporulation septin; mutant has no obvious phenotype; two introns with noncanonical branch site and 5' splice site, respectively; splicing inhibited upon exposure to alpha-factor ||	1	-0.05	-0.41	-0.73	-1.72	0.17	-0.31	-1.22	-0.27
828	|| orf19.6017 ||  ||  || Protein of unknown function; Spider biofilm induced ||	1	0.21	-0.11	-0.25	-0.61	-0.65	-0.86	-0.04	-0.21
829	|| orf19.7296 ||  ||  || Putative cation conductance protein; similar to stomatin mechanoreception protein; plasma-membrane localized; induced by Rgt1; rat catheter and Spider biofilm induced ||	1	0.09	0.02	-0.72	-1.44	-0.31	-1.15	-0.11	-0.88
830	|| orf19.1357 || FCY21 ||  || High affinity, high capacity, hypoxanthine-adenine-guanine-cytosine/H+ symporter; similar to S. cerevisiae Fcy2; mutation confers resistance to 5-fluorocytosine (5-FC); flow model biofilm induced ||	1	0.30	-0.02	-0.76	-0.71	-0.05	-1.19	0.05	-1.59
831	|| orf19.1357 || FCY21 ||  || High affinity, high capacity, hypoxanthine-adenine-guanine-cytosine/H+ symporter; similar to S. cerevisiae Fcy2; mutation confers resistance to 5-fluorocytosine (5-FC); flow model biofilm induced ||	1	0.32	0.17	-0.25	-0.31	-0.24	-0.57	-0.67	-0.83
832	|| orf19.5872 ||  ||  || Predicted ORF from Assembly 19; merged with orf19.5871 in Assembly 20 ||	1	0.22	-0.07	-0.14	-0.53	-1.19	-0.59	-0.66	-1.20
833	|| orf19.7590 ||  ||  || Putative NADH-ubiquinone oxidoreductase; identified in detergent-resistant membrane fraction (possible lipid raft component); predicted N-terminal acetylation; repressed by nitric oxide ||	1	-0.14	-0.21	-0.55	-0.88	0.08	-0.99	-0.71	-0.90
834	|| orf19.4161 ||  ||  || Ortholog(s) have role in DNA repair and Smc5-Smc6 complex, nucleus localization ||	1	-0.10	-0.34	-0.91	-0.74	0.51	-0.81	-0.80	-1.05
835	|| orf19.2231 ||  ||  || Protein of unknown function; Spider biofilm induced ||	1	0.08	-0.23	-0.38	-0.32	0.23	-0.43	-0.68	-1.06
836	|| orf19.6662 ||  ||  || Putative coenzyme Q (ubiquinone) binding protein; transcript is upregulated in clinical isolates from HIV+ patients with oral candidiasis ||	1	0.12	-0.12	-0.11	-0.52	0.22	0.02	-0.63	-0.71
837	|| orf19.2604 ||  ||  || S. pombe ortholog SPAC2C4.06c is a predicted tRNA (cytosine-5-)-methyltransferase; Spider biofilm induced ||	1	0.37	-0.61	-0.47	-1.37	0.40	-0.43	-1.10	-1.20
838	|| orf19.3470 ||  ||  || Putative flavodoxin; similar to S. cerevisiae Tyw1, an iron-sulfur protein required for synthesis of wybutosine modified tRNA; predicted Kex2p substrate; Spider biofilm induced ||	1	0.46	-0.80	-0.09	-1.78	0.57	-0.94	-1.63	-1.76
839	|| orf19.5910 ||  ||  || Putative histone acetyltransferase complex subunit; induced upon low-level peroxide stress; Spider biofilm induced ||	1	0.01	-0.38	-0.07	-0.70	-0.05	-0.50	-0.76	-0.63
840	|| orf19.7565 || GNP3 ||  || Putative high-affinity glutamine permease; fungal-specific (no human or murine homolog) ||	1	0.04	-0.24	-0.05	-0.55	-0.25	-0.25	-0.63	-0.68
841	|| orf19.3170 ||  ||  || Ortholog(s) have role in RNA Polymerase I assembly, RNA Polymerase II core complex assembly, RNA Polymerase III assembly, formation of translation preinitiation complex and cytoplasm, cytosolic ribosome localization ||	1	0.62	-0.64	-0.28	-0.57	0.60	-0.28	-0.66	-1.06
842	|| orf19.6014 || RRS1 ||  || Putative ribosome biogenesis and nuclear export protein; Hap43p-induced gene; mutation confers hypersensitivity to 5-fluorocytosine (5-FC), 5-fluorouracil (5-FU), and tubercidin (7-deazaadenosine) ||	1	1.27	-1.00	-0.65	-0.98	1.28	-0.09	0.32	-1.20
843	|| orf19.1642 ||  ||  || Ortholog of S. cerevisiae Loc1, a nuclear protein involved in asymmetric localization of ASH1 mRNA in S. cerevisiae; Hap43-induced gene; Spider biofilm induced ||	1	1.40	-1.10	-0.70	-1.66	1.31	-0.15	-0.11	-1.53
844	|| orf19.6886 ||  ||  || Ortholog(s) have rRNA binding activity, role in maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA), ribosomal large subunit export from nucleus and nucleolus localization ||	1	1.10	-1.10	-0.80	-1.34	1.02	-0.10	-0.02	-1.41
845	|| orf19.2386 ||  ||  || Ortholog(s) have role in endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA and LSU-rRNA), <a href=#GOsection>more</a> ||	1	0.80	-0.73	-0.76	-1.15	1.01	0.09	0.07	-1.31
846	|| orf19.6862 ||  ||  || Hap43-induced gene; mutation confers hypersensitivity to 5-fluorocytosine (5-FC), 5-fluorouracil (5-FU), and tubercidin (7-deazaadenosine) ||	1	0.81	-0.57	-0.90	-1.39	0.75	-0.14	-0.27	-1.36
847	|| orf19.5353 ||  ||  || Ortholog of <i>C. parapsilosis CDC317</i> : CPAR2_407790, <i>C. dubliniensis CD36</i> : Cd36_24630, <i>Candida orthopsilosis Co 90-125</i> : CORT_0C07130 and <i>Spathaspora passalidarum NRRL Y-27907</i> : SPAPADRAFT_149801 ||	1	0.88	-0.57	-0.67	-1.07	0.51	-0.40	-0.15	-1.41
848	|| orf19.3756 || CHR1 ||  || Predicted DEAD-box ATP-dependent RNA helicase; functional homolog of S. cerevisiae Rok1; Hap43-induced; Spider biofilm induced ||	1	1.00	-0.87	-0.74	-1.03	1.21	-0.24	-0.28	-1.70
849	|| orf19.5959 || NOP14 ||  || Putative nucleolar protein; Hap43-induced; mutation confers resistance to 5-fluorocytosine (5-FC), 5-fluorouracil (5-FU), and tubercidin (7-deazaadenosine); heterozygous mutant is resistant to parnafungin; Spider biofilm induced ||	1	1.15	-0.70	-0.72	-1.34	1.54	-0.54	-0.67	-2.01
850	|| orf19.718 || RRN11 ||  || Putative RNA polymerase I subunit; rat catheter biofilm induced; Spider biofilm induced ||	1	0.36	-0.97	-0.73	-0.72	0.48	-0.16	-0.11	-1.23
851	|| orf19.1082 ||  ||  || Protein with an Alba DNA/RNA-binding protein domain; Spider biofilm induced ||	1	0.73	-1.14	-0.92	-0.87	0.20	-0.03	-0.62	-1.18
852	|| orf19.3478 || NIP7 ||  || Putative nucleolar protein with role in ribosomal assembly; hyphal-induced; Hap43-induced; Spider biofilm induced ||	1	0.43	-1.10	-1.20	-0.87	0.20	-0.00	-0.60	-1.17
853	|| orf19.6955 || HBR3 ||  || Essential protein; regulated by hemoglobin; S. cerevisiae ortholog is essential; Hap43p-induced gene ||	1	0.42	-0.67	-1.08	-0.95	0.63	0.39	-0.51	-0.99
854	|| orf19.3539 ||  ||  || Predicted nucleolar S-adenosylmethionine-dependent rRNA methyltransferase; Spider biofilm induced ||	1	0.12	-0.78	-0.89	-0.93	0.54	0.18	-0.52	-0.87
855	|| orf19.58 || RRP6 ||  || Putative nuclear exosome exonuclease component; Hap43p-induced gene; mutation confers hypersensitivity to 5-fluorocytosine (5-FC), 5-fluorouracil (5-FU), and tubercidin (7-deazaadenosine) ||	1	0.34	-0.85	-0.66	-0.69	0.29	0.17	-0.28	-0.62
856	|| orf19.3778 ||  ||  || Protein with a predicted role in ribosome biogenesis; mutation confers hypersensitivity to 5-fluorocytosine (5-FC), 5-fluorouracil (5-FU); repressed in core stress response; repressed by prostaglandins; Hap43-induced ||	1	0.34	-0.74	-0.89	-0.63	0.26	0.06	-0.24	-0.53
857	|| orf19.6766 || NOP13 ||  || Ortholog of S. cerevisiae Nop13; a nucleolar protein found in preribosomal complexes; Hap43-induced gene; rat catheter biofilm induced ||	1	0.42	-0.91	-0.94	-0.84	0.38	0.05	-0.33	-0.73
858	|| orf19.6418 ||  ||  || Ortholog(s) have role in ribosomal large subunit biogenesis and cytoplasm, nucleus localization ||	1	0.28	-0.84	-0.84	-0.64	0.28	0.06	-0.39	-0.64
859	|| orf19.3276 || PWP2 ||  || Putative 90S pre-ribosomal component; repressed in core stress response; repressed by prostaglandins; physically interacts with TAP-tagged Nop1; Hap43-induced ||	1	0.51	-1.03	-1.07	-0.90	0.47	-0.07	-0.47	-1.10
860	|| orf19.6648 || SDA1 ||  || Predicted nuclear protein involved in actin cytoskeleton organization, passage through Start, 60S ribosome biogenesis; rat catheter biofilm induced; Hap43-induced ||	1	0.53	-1.01	-1.16	-0.98	0.46	-0.05	-0.41	-1.14
861	|| orf19.1687 ||  ||  || Ortholog of S. cerevisiae Prp43, an RNA helicase in the DEAH-box family that functions in both RNA polymerase I and polymerase II transcript metabolism; Hap43-induced gene ||	1	0.38	-0.71	-0.90	-0.70	0.38	0.00	-0.39	-0.87
862	|| orf19.3393 ||  ||  || Putative DEAD-box helicase; Hap43-induced; Spider biofilm induced ||	1	0.47	-1.01	-1.03	-1.10	0.58	0.17	-0.58	-1.10
863	|| orf19.1902 || NOC4 ||  || Putative nucleolar protein; Hap43-induced; mutation confers resistance to 5-fluorocytosine (5-FC), 5-fluorouracil (5-FU), and tubercidin (7-deazaadenosine); Spider biofilm induced ||	1	0.49	-0.97	-1.29	-1.20	0.47	0.05	-0.61	-1.10
864	|| orf19.4896 || RPA34 ||  || Putative RNA polymerase I subunit; rat catheter biofilm induced ||	1	0.32	-0.56	-0.78	-0.73	0.40	0.08	-0.27	-0.62
865	|| orf19.2998 || TSR2 ||  || Protein with a predicted role in pre-rRNA processing; repressed by prostaglandins ||	1	0.49	-0.93	-1.08	-0.82	0.72	0.05	-0.39	-0.96
866	|| orf19.2185 || NSA1 ||  || Putative 66S pre-ribosomal particles conmponent; Hap43-induced; repressed by prostaglandins ||	1	0.43	-0.98	-0.97	-0.83	0.72	0.10	-0.53	-1.04
867	|| orf19.4479 ||  ||  || Putative U3-containing 90S preribosome subunit; Hap43-induced; repressed in core stress response; Spider biofilm induced ||	1	0.64	-0.88	-0.64	-0.69	0.70	-0.04	-0.12	-0.93
868	|| orf19.7107 ||  ||  || Ortholog(s) have role in ribosomal large subunit biogenesis and cytoplasm, nucleus, ribosome localization ||	1	0.37	-0.99	-0.77	-0.66	0.55	-0.11	-0.06	-0.67
869	|| orf19.3676 || ABP140 ||  || Ortholog of S. cerevisiae actin-binding protein Abp140; Hap43-induced; F-12/CO2 early biofilm induced ||	1	0.63	-1.18	-0.89	-1.08	0.74	-0.04	-0.39	-0.97
870	|| orf19.2527 ||  ||  || Putative protein of unknown function; Hap43-induced; required for normal biofilm growth; F-12/CO2 early biofilm induced ||	1	0.50	-0.95	-0.84	-0.73	0.70	-0.12	-0.25	-0.78
871	|| orf19.5232 || CSI2 ||  || Putative 66S pre-ribosomal particle component; Hap43-induced; essential for growth; transposon mutation affects filamentous growth; Spider biofilm induced ||	1	0.61	-1.08	-0.86	-0.77	0.77	0.06	-0.03	-0.86
872	|| orf19.6828 ||  ||  || Ortholog(s) have role in rRNA processing and nucleolus, preribosome, large subunit precursor localization ||	1	1.00	-1.55	-1.35	-1.34	0.99	0.12	-0.23	-1.30
873	|| orf19.6902 || DBP7 ||  || Putative ATP-dependent DEAD-box RNA helicase; Hap43-induced; rat catheter biofilm induced ||	1	0.65	-1.05	-1.10	-0.83	0.57	0.08	-0.14	-0.83
874	|| orf19.2667 || RPF1 ||  || Putative nucleolar protein with a predicted role in the assembly and export of the large ribosomal subunit; essential for growth; rat catheter and Spider biofilm induced ||	1	0.61	-0.88	-0.97	-0.79	0.48	0.15	-0.06	-0.80
875	|| orf19.2090 ||  ||  || Ortholog of S. cerevisiae Ecm16, an essential DEAH-box ATP-dependent RNA helicase specific to the U3 snoRNP required for 18S rRNA synthesis; Hap43-induced; Spider biofilm induced ||	1	0.50	-0.85	-0.85	-0.88	0.50	0.02	-0.30	-0.89
876	|| orf19.4793 ||  ||  || Putative ribosome-associated protein; ortholog of S. cerevisiae Tma16; Hap43-induced gene; Spider biofilm induced ||	1	0.52	-0.97	-1.01	-1.02	0.53	0.12	-0.33	-1.09
877	|| orf19.5106 || DIP2 ||  || Putative small ribonucleoprotein complex; Tn mutation affects filamentous growth; physically interacts with TAP-tagged Nop1; heterozygous null mutant exhibits resistance to parnafungin; Hap43-induced gene; Spider biofilm induced ||	1	0.60	-0.81	-0.87	-0.93	0.50	0.10	-0.41	-1.05
878	|| orf19.7599 || UTP5 ||  || Putative U3 snoRNA-associated protein; Hap43p-induced gene; mutation confers resistance to 5-fluorocytosine (5-FC), 5-fluorouracil (5-FU), and tubercidin (7-deazaadenosine); physically interacts with TAP-tagged Nop1p ||	1	0.60	-0.77	-0.73	-0.89	0.55	-0.01	-0.32	-0.94
879	|| orf19.563 || RRP15 ||  || Putative nucleolar protein; constituent of pre-60S ribosomal particles; Hap43-induced; repressed by prostaglandins ||	1	0.70	-0.87	-0.95	-1.15	0.66	-0.01	-0.45	-1.08
880	|| orf19.59 || REI1 ||  || Putative cytoplasmic pre-60S factor; Hap43-induced; repressed by prostaglandins ||	1	0.83	-0.91	-1.15	-1.14	0.76	0.04	-0.27	-1.32
881	|| orf19.7384 || NOG1 ||  || Putative GTPase; mutation confers hypersensitivity to 5-fluorocytosine (5-FC), 5-fluorouracil (5-FU), and tubercidin (7-deazaadenosine); repressed by prostaglandins; Hap43-induced ||	1	0.54	-0.83	-0.89	-0.87	0.55	-0.19	-0.20	-1.08
882	|| orf19.3463 ||  ||  || Putative GTPase; role in 60S ribosomal subunit biogenesis; Spider biofilm induced ||	1	0.64	-0.70	-0.79	-1.00	0.67	-0.13	-0.33	-1.06
883	|| orf19.4760 ||  ||  || Putative protein-histidine N-methyltransferase; Spider biofilm induced ||	1	0.71	-1.07	-1.16	-1.36	0.97	-0.29	-0.39	-1.51
884	|| orf19.2712 || HCA4 ||  || Putative role in regulation of cell wall biogenesis; Hap43p-induced gene; possibly an essential gene, disruptants not obtained by UAU1 method; flow model and rat catheter biofilm induced ||	1	0.59	-0.94	-0.86	-1.07	0.86	-0.04	-0.35	-1.14
885	|| orf19.124 || CIC1 ||  || Putative proteasome-interacting protein; rat catheter biofilm induced ||	1	0.90	-0.88	-0.92	-0.98	0.88	0.16	-0.22	-1.03
886	|| orf19.1708 ||  ||  || Protein of unknown function; Spider biofilm induced ||	1	1.17	-0.97	-1.15	-1.51	1.07	0.08	-0.17	-1.39
887	|| orf19.2287 || RPA12 ||  || Putative DNA-directed RNA polymerase I; induced upon adherence to polystyrene ||	1	0.85	-0.98	-0.90	-1.04	0.73	0.04	-0.07	-1.25
888	|| orf19.6234 ||  ||  || Putative U2 snRNP component; mutation confers hypersensitivity to 5-fluorocytosine (5-FC), 5-fluorouracil (5-FU), and tubercidin (7-deazaadenosine); Hap43-induced, Spider biofilm induced ||	1	0.88	-0.91	-0.77	-1.17	0.62	-0.11	-0.16	-1.24
889	|| orf19.2320 ||  ||  || Putative serine/threonine-protein kinase; possibly an essential gene, disruptants not obtained by UAU1 method ||	1	0.75	-1.20	-0.88	-1.68	0.76	-0.08	-0.51	-1.30
890	|| orf19.7422 ||  ||  || Ortholog(s) have RNA binding activity and nucleus localization ||	1	0.53	-0.86	-0.72	-0.93	0.56	-0.31	-0.40	-0.73
891	|| orf19.1566 || UTP21 ||  || Putative U3 snoRNP protein; Hap43-induce; physically interacts with TAP-tagged Nop1; Spider biofilm induced ||	1	0.70	-0.94	-0.77	-1.12	0.46	-0.25	-0.60	-1.30
892	|| orf19.494 ||  ||  || Putative RNA-binding protein; role in assembly of box H/ACA snoRNPs and thus pre-rRNA processing; Spider biofilm induced ||	1	0.32	-0.88	-0.98	-1.00	0.56	-0.17	-0.78	-1.43
893	|| orf19.2934 ||  ||  || Similar to S. cerevisiae Bud20; predicted role in cellular bud site selection; rat catheter and Spider biofilm induced ||	1	0.66	-1.08	-1.34	-1.33	0.83	-0.43	-0.79	-1.98
894	|| orf19.3287 || BUD22 ||  || Protein with a predicted role in 18S rRNA maturation and small ribosomal subunit biogenesis; repressed in core stress response; repressed by prostaglandins ||	1	0.59	-0.67	-1.19	-1.09	0.42	-0.12	-0.47	-1.21
895	|| orf19.1886 || RCL1 ||  || Putative U3-containing 90S preribosome processome complex subunit; Hap43-induced; essential; S. cerevisiae ortholog is essential; represses in core stress response; ||	1	0.50	-0.49	-0.72	-0.87	0.34	-0.10	-0.33	-0.77
896	|| orf19.5507 || ENP1 ||  || Protein required for pre-rRNA processing and 40S ribosomal subunit synthesis; associated with U3 and U14 snoRNAs; transposon mutation affects filamentous growth; repressed by prostaglandins; Spider biofilm induced ||	1	0.54	-0.82	-1.07	-1.32	0.40	0.07	-0.55	-1.24
897	|| orf19.5010 || DIM1 ||  || Putative 18S rRNA dimethylase; predicted role in rRNA modification and processing; Hap43-induced; likely to be essential for growth based on insertional mutagenesis strategy; F-12/CO2 early biofilm induced ||	1	0.70	-0.81	-1.45	-1.49	0.89	0.25	-0.73	-1.74
898	|| orf19.3327 || TRM2 ||  || Putative tRNA methyltransferase; repressed by prostaglandins; Spider biofilm induced ||	1	0.52	-0.59	-0.96	-1.01	0.55	0.01	-0.52	-1.17
899	|| orf19.2830 || RRP9 ||  || Ribosomal protein; mutation confers resistance to 5-fluorocytosine (5-FC), 5-fluorouracil (5-FU), and tubercidin (7-deazaadenosine); physically interacts with TAP-tagged Nop1; Hap43-induced; Spider biofilm induced ||	1	0.65	-0.70	-1.02	-1.26	0.78	-0.03	-0.51	-1.17
900	|| orf19.6298 || SPB4 ||  || Putative ATP-dependent RNA helicase; flucytosine repressed; Spider biofilm induced ||	1	0.54	-0.82	-0.88	-1.04	0.68	0.10	-0.74	-1.16
901	|| orf19.6052 || CNS1 ||  || Putative co-chaperone; Hap43p-induced gene; mutation confers hypersensitivity to radicicol ||	1	0.31	-0.53	-0.64	-0.71	0.37	-0.02	-0.52	-0.85
902	|| orf19.6297 ||  ||  || Ortholog(s) have pseudouridine synthase activity, role in tRNA pseudouridine synthesis and cytosol, nucleus localization ||	1	0.63	-0.49	-0.70	-0.83	0.45	-0.14	-0.60	-1.20
903	|| orf19.107 ||  ||  || DEAH-box ATP-dependent RNA helicase, required for 18S rRNA synthesis; rat catheter biofilm induced ||	1	0.54	-0.62	-0.70	-0.94	0.49	-0.05	-0.50	-1.28
904	|| orf19.7650 || LTV1 ||  || Putative GSE complex component; repressed by prostaglandins ||	1	0.53	-0.42	-0.67	-0.84	0.62	-0.09	-0.35	-1.10
905	|| orf19.5500 || MAK16 ||  || Putative constituent of 66S pre-ribosomal particles; Hap43-induced; repressed by prostaglandins; Spider biofilm induced ||	1	0.76	-0.67	-1.11	-1.46	0.93	0.20	-0.96	-1.99
906	|| orf19.4401 || YVH1 ||  || Putative dual specificity phosphatase (phosphoserine/threonine and phosphotyrosine phosphatase); required for wild-type growth rate and for wild-type virulence in mouse model of systemic infection; Hap43p-induced gene ||	1	0.42	-0.75	-0.65	-1.00	0.70	0.04	-0.34	-1.26
907	|| orf19.6652 || DBP8 ||  || Protein similar to S. cerevisiae Dbp8p, an ATP-dependent helicase involved in rRNA processing; oxidative stress-repressed via Cap1p; flucytosine repressed; likely to be essential for growth, based on insertional mutagenesis ||	1	0.66	-0.93	-0.95	-0.82	0.82	-0.18	-0.46	-1.54
908	|| orf19.6431 ||  ||  || Protein of unknown function; Spider biofilm induced ||	1	0.54	-0.53	-0.64	-0.64	0.62	-0.34	-0.19	-0.90
909	|| orf19.5299 || ECM1 ||  || Putative pre-ribosomal factor; decreased mRNA abundance observed in cyr1 homozygous mutant hyphae; induced by heavy metal (cadmium) stress; Hog1p regulated ||	1	0.89	-0.69	-0.88	-0.71	0.65	-0.17	-0.26	-1.16
910	|| orf19.2319 ||  ||  || Putative nucleolar protein with a predicted role in pre-rRNA processing; Hap43-induced gene; repressed in core stress response ||	1	0.97	-0.85	-0.80	-0.75	0.71	0.00	-0.19	-1.10
911	|| orf19.6686 || ENP2 ||  || Putative nucleolar protein; essential; heterozygous mutation confers resistance to 5-fluorocytosine (5-FC), 5-fluorouracil (5-FU), and tubercidin (7-deazaadenosine); Hap43-induced; Spider biofilm induced ||	1	0.61	-1.08	-1.53	-1.01	0.66	-0.01	-0.19	-1.61
912	|| orf19.2362 ||  ||  || Putative 90S preribosome component; Hap43p-induced gene; possibly an essential gene, disruptants not obtained by UAU1 method ||	1	0.43	-0.61	-1.12	-0.81	0.60	-0.11	-0.20	-1.08
913	|| orf19.962 ||  ||  || Protein with a fungal RNA polymerase I subunit RPA14 domain; proposed to play a role in the recruitment of pol I to the promoter; Hap43-induced gene ||	1	0.33	-0.70	-1.27	-0.76	0.63	-0.09	-0.18	-0.85
914	|| orf19.4835 ||  ||  || Ortholog(s) have role in endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA and LSU-rRNA), <a href=#GOsection>more</a> ||	1	0.26	-0.56	-0.64	-0.70	0.73	-0.30	-0.35	-0.81
915	|| orf19.1404 ||  ||  || Predicted tRNA dihydrouridine synthase; Spider biofilm induced ||	1	0.36	-0.56	-0.76	-0.62	0.61	-0.27	-0.52	-0.89
916	|| orf19.5039 || RRP42 ||  || Putative exosome non-catalytic core component; involved in 3'-5' RNA processing; rat catheter biofilm induced ||	1	0.63	-0.32	-0.85	-0.69	0.71	-0.16	-0.43	-0.97
917	|| orf19.1388 ||  ||  || Putative 66S pre-ribosomal particle component; Hap43-induced; F-12/CO2 early biofilm induced ||	1	0.58	-1.03	-1.03	-1.02	0.65	0.15	-1.15	-1.10
918	|| orf19.1646 ||  ||  || Ortholog(s) have rRNA primary transcript binding activity ||	1	0.49	-0.82	-0.79	-0.91	0.45	0.07	-0.58	-0.50
919	|| orf19.7154 || UTP18 ||  || Putative U3 snoRNA-associated protein; Hap43-induced; repressed in core stress response; physically interacts with TAP-tagged Nop1 ||	1	0.28	-0.69	-1.29	-1.06	0.16	0.10	-0.64	-0.80
920	|| orf19.5436 || UTP8 ||  || Essential nucleolar protein; involved in tRNA export from the nucleus and ribosomal small subunit biogenesis; physically interacts with TAP-tagged Nop1; Spider biofilm induced ||	1	0.12	-0.52	-0.89	-0.71	0.03	0.11	-0.45	-0.67
921	|| orf19.5430 || BUD21 ||  || Small-subunit processome component; repressed by prostaglandins ||	1	0.16	-0.82	-1.23	-1.25	0.24	0.21	-0.52	-1.08
922	|| orf19.2385 || KTI12 ||  || Protein similar to S. cerevisiae Kti12p, which associates with Elongator complex; has a role in resistance to killer toxin; predicted Kex2p substrate; Hap43p-induced gene ||	1	0.29	-0.52	-1.11	-1.01	0.55	-0.14	-0.52	-1.02
923	|| orf19.7657 || POP3 ||  || Putative RNase MRP and nuclear RNase P component; decreased repressed by prostaglandins; Spider biofilm induced ||	1	0.22	-0.44	-1.15	-1.02	0.37	0.09	-0.59	-1.01
924	|| orf19.2735 || SEN2 ||  || Putative tRNA splicing endonuclease subunit; mutation confers hypersensitivity to toxic ergosterol analog and to amphotericin B; 5'-UTR intron; Hap43-induced; Spider biofilm induced ||	1	0.36	-0.96	-1.31	-1.83	0.27	0.09	-0.98	-1.52
925	|| orf19.5038 ||  ||  || Predicted tRNA (guanine) methyltransferase activity; Spider biofilm induced ||	1	0.33	-0.68	-0.95	-1.13	0.14	0.10	-0.58	-1.17
926	|| orf19.603 || IMP4 ||  || Putative SSU processome component; Hap43-induced; repressed by prostaglandins; Spider biofilm induced ||	1	0.21	-0.61	-0.67	-0.85	0.30	0.12	-0.53	-0.91
927	|| orf19.5567 || POP4 ||  || Ortholog of S. cerevisiae Pop4; a subunit of both RNase MRP and nuclear RNase P; filament induced; regulated by Nrg1, Tup1; likely essential, based on UAU1 strategy; rat catheter and Spider biofilm induced ||	1	0.26	-0.46	-0.70	-0.73	0.33	-0.13	-0.54	-0.68
928	|| orf19.4375 ||  ||  || Ortholog(s) have S-adenosylmethionine-dependent methyltransferase activity, role in chromatin silencing at rDNA, nicotinamide metabolic process and cytosol localization ||	1	0.06	-0.46	-0.74	-0.77	0.19	-0.13	-0.39	-0.80
929	|| orf19.3303 ||  ||  || Ortholog(s) have tRNA methyltransferase activity, role in tRNA methylation, wybutosine biosynthetic process and cytosol, mitochondrion, nucleus localization ||	1	0.19	-0.64	-0.85	-0.90	0.19	-0.18	-0.57	-0.85
930	|| orf19.2604 ||  ||  || S. pombe ortholog SPAC2C4.06c is a predicted tRNA (cytosine-5-)-methyltransferase; Spider biofilm induced ||	1	0.38	-0.88	-1.31	-1.50	0.44	-0.39	-0.76	-1.34
931	|| orf19.4940 ||  ||  || Putative histidine permease; fungal-specific (no human or murine homolog); Hap43p-induced gene ||	1	0.31	-0.46	-0.74	-0.67	0.25	-0.07	-0.45	-0.82
932	|| orf19.3088 ||  ||  || bZIP transcription factor; possibly transcriptionally regulated upon hyphal formation; Hap43; F-12/CO2 early biofilm induced; Spider biofilm induced ||	1	0.37	-0.91	-1.36	-1.18	0.40	0.03	-0.85	-1.35
933	|| orf19.6710 || UTP9 ||  || Small-subunit processome protein; Ssr1-induced; repressed by prostaglandins; physically interacts with TAP-tagged Nop1 ||	1	0.10	-0.64	-0.89	-0.63	0.21	-0.01	-0.58	-0.88
934	|| orf19.3609 || UTP15 ||  || Small subunit (SSU) processome component; mutation confers resistance to 5-fluorocytosine (5-FC); physically interacts with TAP-tagged Nop1p ||	1	0.09	-0.67	-0.84	-0.70	0.35	-0.15	-0.56	-0.82
935	|| orf19.2330 ||  ||  || Putative U3 snoRNA-associated protein; Hap43-induced; transposon mutation affects filamentous growth; repressed by prostaglandins ||	1	0.21	-0.87	-1.23	-1.12	0.25	-0.12	-1.07	-1.09
936	|| orf19.7387 || ELP3 ||  || Predicted histone acetyltransferase; role in regulation of transcription, tRNA wobble uridine modification; Spider biofilm induced ||	1	0.20	-0.54	-0.72	-0.80	0.10	-0.06	-0.67	-0.88
937	|| orf19.3704 ||  ||  || Ortholog(s) have role in maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA), maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) ||	1	0.19	-0.67	-0.69	-0.67	0.08	-0.12	-0.52	-0.86
938	|| orf19.6938 || MEU1 ||  || Putative methylthioadenosine phosphorylase; protein level decreases in stationary phase cultures ||	1	0.20	-0.59	-0.66	-0.69	-0.02	-0.09	-0.47	-0.58
939	|| orf19.4499 || RIM2 ||  || Putative mitochondrial carrier protein; induced by alpha pheromone in SpiderM medium; Spider biofilm induced ||	1	0.10	-0.45	-0.72	-0.81	-0.14	-0.06	-0.49	-0.81
940	|| orf19.169 || CHO2 ||  || Putative phosphatidyl-ethanolamine N-methyltransferase; fungal-specific (no human or murine homolog); amphotericin B repressed; Hap43p-induced gene ||	1	0.09	-0.55	-0.73	-1.00	-0.22	-0.25	-0.82	-1.00
941	|| orf19.2018 ||  ||  || Protein with a predicted DnaJ chaperone domain and a CSL-type zinc finger; Spider biofilm induced ||	1	0.15	-0.78	-0.99	-1.43	-0.00	-0.30	-1.09	-1.30
942	|| orf19.3034 || RLI1 ||  || Member of RNase L inhibitor (RLI) subfamily of ABC family; predicted not to be a transporter; regulated by Sef1p, Sfu1p, and Hap43p ||	1	0.17	-0.54	-0.71	-0.98	0.10	-0.22	-0.68	-0.99
943	|| orf19.4445 ||  ||  || Protein of unknown function; Plc1p-regulated; expression induced early upon infection of reconstituted human epithelium (RHE), while expression of the C. dubliniensis ortholog is not; mutant is viable; Spider biofilm induced ||	1	-0.06	-1.29	-2.37	-2.90	0.24	-1.00	-1.94	-2.79
944	|| orf19.5020 ||  ||  || Protein of unknown function; Hap43-induced; Spider biofilm induced ||	1	0.27	-0.61	-1.36	-1.76	0.24	-0.21	-1.12	-1.74
945	|| orf19.3854 ||  ||  || Ortholog of S. cerevisiae Sat4; amphotericin B induced; clade-associated gene expression; Spider biofilm induced ||	1	0.11	-0.20	-0.63	-1.01	0.10	-0.20	-0.67	-0.79
946	|| orf19.1771 || CWC22 ||  || Predicted spliceosome-associated protein; role in pre-mRNA splicing; Spider biofilm induced ||	1	0.39	-0.39	-1.16	-1.41	0.36	-0.72	-1.16	-1.33
947	|| orf19.3759 ||  ||  || Putative elongator complex subunit; for modification of wobble nucleosides in tRNA; Spider biofilm induced ||	1	-0.08	-0.37	-1.33	-1.23	0.37	-0.50	-1.10	-1.18
948	|| orf19.3252 || DAL81 ||  || Zn(II)2Cys6 transcription factor; ortholog of S. cerevisiae Dal81, involved in the regulation of nitrogen-degradation genes; required for yeast cell adherence to silicone substrate; Spider biofilm induced ||	1	-0.11	-0.55	-0.92	-1.09	0.03	-0.33	-0.29	-0.97
949	|| orf19.353 || ULP1 ||  || SUMO deconjugation enzyme that cleaves the small ubiquitin-like modifier (SUMO) off proteins ||	1	-0.24	-0.70	-0.77	-0.66	0.05	-0.33	-0.36	-0.70
950	|| orf19.6137 ||  ||  || Ortholog of <i>C. dubliniensis CD36</i> : Cd36_32940, <i>Candida tenuis NRRL Y-1498</i> : CANTEDRAFT_134955, <i>Debaryomyces hansenii CBS767</i> : DEHA2E04422g and <i>Pichia stipitis Pignal</i> : PICST_33357 ||	1	-0.06	-0.84	-0.84	-0.72	0.02	-0.48	-0.61	-0.84
951	|| orf19.2306 ||  ||  || Ortholog(s) have acireductone dioxygenase (Ni2+-requiring) activity, role in L-methionine salvage from methylthioadenosine and cytosol, nucleus localization ||	1	-0.04	-0.56	-0.71	-0.66	0.03	-0.31	-0.45	-0.89
952	|| orf19.1959 ||  ||  || Ortholog(s) have ubiquitin-specific protease activity, role in protein deubiquitination and cytosol, ribosome localization ||	1	0.09	-0.45	-0.84	-0.65	0.08	-0.27	-0.48	-0.86
953	|| orf19.2045 ||  ||  || Ortholog(s) have diacylglycerol kinase activity, role in phosphatidic acid biosynthetic process and integral to endoplasmic reticulum membrane localization ||	1	0.04	-0.49	-0.78	-0.63	-0.04	-0.16	-0.39	-0.64
954	|| orf19.4342 || SUT1 ||  || Zn2Cys6 transcription factor involved in sterol uptake; flow model biofilm induced; Spider biofilm repressed ||	1	0.10	-0.61	-0.65	-0.77	-0.23	-0.39	-0.57	-0.91
955	|| orf19.4274 || PUT1 ||  || Putative proline oxidase; alkaline upregulated by Rim101; flow model biofilm induced; Spider biofilm induced ||	1	0.29	-0.35	-0.84	-0.93	0.06	-0.50	-0.46	-0.75
956	|| orf19.1697 ||  ||  || Ortholog(s) have role in cytoplasmic translation and cytoplasm, polysomal ribosome localization ||	1	0.21	-0.38	-0.77	-0.94	0.38	-0.25	-0.28	-0.72
957	|| orf19.6723 ||  ||  || Protein of unknown function; Spider biofilm induced ||	1	0.37	-0.46	-0.73	-0.77	0.11	-0.46	-0.37	-0.79
958	|| orf19.7593 ||  ||  || Putative asparaginase; predicted role in asparagine catabolism; Spider biofilm induced ||	1	0.40	-0.55	-0.75	-0.92	0.20	-0.36	-0.39	-0.83
959	|| orf19.6140 || FRE30 ||  || Protein with similarity to ferric reductases; downregulated in response to amphotericin B, estradiol, or ciclopirox olamine, and upregulated by interaction with macrophage; un-merged from orf19.6139 in a revision of Assembly 21 ||	1	0.50	-1.05	-1.52	-1.87	0.28	-0.65	-0.72	-1.68
960	|| orf19.5802 ||  ||  || Ortholog(s) have role in maturation of SSU-rRNA and cytoplasm, nucleus localization ||	1	0.33	-0.67	-0.65	-0.94	0.29	-0.47	-0.41	-0.80
961	|| orf19.7362 || SKN1 ||  || Protein with a role in beta-1,6-glucan synthesis; probable N-glycosylated type II membrane protein; transcript and mRNA length change induced by yeast-hypha transition; induced by Rim101, caspofungin; rat catheter and Spider biofilm induced ||	1	0.58	-1.21	-1.55	-1.98	0.31	-0.61	-0.33	-1.57
962	|| orf19.443 ||  ||  || Ortholog(s) have DNA-directed RNA polymerase activity, RNA polymerase III activity and role in tRNA transcription from RNA polymerase III promoter, transcription initiation from RNA polymerase III promoter ||	1	0.34	-0.65	-0.64	-0.75	0.14	-0.18	-0.17	-0.68
963	|| orf19.6078 || POL93 ||  || Predicted ORF in retrotransposon Tca8 with similarity to the Pol region of retrotransposons encoding reverse transcriptase, protease and integrase; downregulated in response to ciclopirox olamine; F-12/CO2 early biofilm induced ||	1	0.24	-0.56	-0.70	-0.82	-0.03	-0.39	-0.11	-0.67
964	|| orf19.7495 ||  ||  || Protein with NADPH oxidoreductase containing flavin mononucleotide (FMN) domain; induced by nitric oxide ||	1	0.28	-0.70	-0.67	-0.79	0.25	-0.40	-0.08	-0.60
965	|| orf19.2547 ||  ||  || Has domain(s) with predicted RNA binding, ribonuclease activity ||	1	0.34	-0.46	-0.91	-1.38	0.07	-0.47	-0.43	-1.44
966	|| orf19.5704 ||  ||  || Ortholog(s) have rRNA binding activity, role in mitochondrial RNA processing, mitochondrial genome maintenance, rRNA metabolic process and mitochondrion localization ||	1	0.25	-0.76	-0.80	-1.15	0.17	-0.21	-0.58	-1.39
967	|| orf19.2384 || MTG1 ||  || Putative mitochondrial GTPase; likely essential for respiratory competence and in large ribosomal subunit assembly; mitochondrial translation; Spider biofilm induced ||	1	0.60	-0.41	-0.74	-1.22	0.24	-0.41	-0.53	-1.56
968	|| orf19.5732 || NOG2 ||  || Putative nucleolar GTPase; repressed by prostaglandins; Hap43-induced, rat catheter and Spider biofilm induced ||	1	0.45	-0.77	-0.83	-1.36	0.50	-0.44	-0.83	-2.10
969	|| orf19.1362 || SMM1 ||  || Putative dihydrouridine synthase; Hap43-induced gene; rat catheter biofilm induced; Spider biofilm induced ||	1	0.48	-0.67	-1.09	-1.91	0.49	-0.50	-1.14	-1.99
970	|| orf19.2547 ||  ||  || Has domain(s) with predicted RNA binding, ribonuclease activity ||	1	0.37	-0.64	-0.54	-1.12	0.16	-0.38	-0.69	-1.28
971	|| orf19.4143 || FYV5 ||  || Protein with a predicted role maturation of 18S rRNA; rat catheter biofilm induced ||	1	0.58	-0.66	-0.37	-1.39	0.29	-0.30	-0.82	-1.41
972	|| orf19.6873.1 || KTI11 ||  || Zn-ribbon protein; required for synthesis of diphthamide on translation factor eEF2; involved in modification of wobble nucleosides in tRNAs; rat catheter and Spider biofilm induced ||	1	1.11	-0.31	-1.74	-2.36	0.69	-0.13	-1.10	-2.71
973	|| orf19.4273 ||  ||  || Putative mitochondrial membrane protein; ortholog of S. cerevisiae Sls1; coordinates expression of mitochondrially-encoded genes; Hap43-induced ||	1	0.66	-0.55	-0.93	-1.34	0.32	0.10	-0.89	-1.58
974	|| orf19.1287 ||  ||  || Protein of unknown function; flow model biofilm induced; Spider biofilm induced ||	1	0.78	-0.28	-0.66	-1.07	0.57	0.15	-0.73	-1.21
975	|| orf19.7088 ||  ||  || Ortholog(s) have single-stranded telomeric DNA binding activity, role in regulation of translational fidelity, telomere maintenance, threonylcarbamoyladenosine metabolic process and cytosol, nucleus localization ||	1	0.39	-0.44	-0.88	-0.69	0.47	0.19	-0.65	-1.06
976	|| orf19.6751 ||  ||  || Ortholog(s) have tRNA methyltransferase activity, role in cytoplasmic translation, tRNA methylation and cytoplasm localization ||	1	0.28	-0.38	-0.79	-0.63	0.32	0.06	-0.63	-0.93
977	|| orf19.4634 ||  ||  || Protein required for thiolation of uridine at wobble position of Gln, Lys, and Glu tRNAs; has a role in urmylation; S. cerevisiae ortholog has a role in invasive and pseudohyphal growth ||	1	0.69	-0.65	-0.73	-0.72	0.24	-0.02	-0.70	-1.17
978	|| orf19.5049 ||  ||  || Putative U3-containing 90S preribosome processome complex subunit; Hap43-induced gene; rat catheter and Spider biofilm induced; F-12/CO2 early biofilm induced ||	1	0.91	-0.86	-0.95	-0.87	0.50	-0.11	-1.31	-2.21
979	|| orf19.7468 ||  ||  || Putative transcriptional activator; expression upregulated during growth in the mouse cecum; Spider biofilm induced ||	1	0.18	-0.10	-0.92	-0.79	0.29	-0.11	-0.49	-1.16
980	|| orf19.5926 || ARG11 ||  || Putative ornithine transporter of the mitochondrial inner membrane; induced during the mating process ||	1	0.03	-0.17	-1.29	-1.12	0.36	-0.29	-0.98	-1.54
981	|| orf19.7190 || OGG1 ||  || Mitochondrial glycosylase/lyase; repairs oxidative damage to mitochondrial DNA, contributes to UVA resistance, role in base-excision repair; Spider biofilm induced ||	1	0.34	-0.27	-1.30	-0.71	0.31	-0.34	-0.42	-0.84
982	|| orf19.4792 ||  ||  || Protein with a regulator of G-protein signaling domain; Plc1-regulated; Spider biofilm induced; rat catheter biofilm repressed ||	1	0.45	-0.41	-1.10	-0.77	0.23	-0.18	-0.28	-0.97
983	|| orf19.4662 || RLM1 ||  || Putative transcription factor; required for wild-type resistance to cell wall perturbation, caspofungin treatment; regulates caspofungin induction of PGA13 ||	1	0.22	-0.25	-0.92	-0.76	0.03	-0.40	-0.15	-0.90
984	|| orf19.5905 ||  ||  || Protein of unknown function; Hap43-induced; F-12/CO2 early biofilm induced ||	1	0.19	-0.90	-0.90	-1.32	0.63	-0.90	-0.14	-2.25
985	|| orf19.1091 || NOP8 ||  || Ortholog of S. cereviiae Nop8; has a role in ribosomal large subunit biogenesis; rat catheter and Spider biofilm induced ||	1	0.58	-1.21	-1.28	-1.80	0.89	-1.10	-0.82	-2.49
986	|| orf19.2167 ||  ||  || Ortholog(s) have role in ribosomal large subunit biogenesis, ribosomal small subunit biogenesis and cytosolic large ribosomal subunit, nucleolus localization ||	1	0.30	-0.45	-0.64	-0.75	0.63	-0.68	-0.37	-1.21
987	|| orf19.4815 || YTM1 ||  || Protein similar to S. cerevisiae Ytm1p, which is involved in biogenesis of the large ribosomal subunit; transposon mutation affects filamentous growth; protein level decreases in stationary phase cultures; Hap43p-induced gene ||	1	0.15	-0.76	-1.33	-0.63	0.37	-0.06	-0.56	-0.92
988	|| orf19.3887 ||  ||  || Ortholog(s) have cytoplasm, nucleus localization ||	1	0.07	-0.68	-1.16	-0.67	0.24	-0.02	-0.53	-0.60
989	|| orf19.3015 || ARX1 ||  || Putative ribosomal large subunit biogenesis protein; repressed in core stress response; repressed by prostaglandins ||	1	0.21	-0.99	-1.24	-0.69	0.31	-0.07	-0.56	-0.68
990	|| orf19.7011 ||  ||  || Ortholog(s) have 90S preribosome, cytoplasm, mitotic spindle pole body, nucleolus localization ||	1	0.23	-0.99	-0.89	-0.68	0.07	-0.18	-0.41	-0.57
991	|| orf19.1449 ||  ||  || Protein of unknown function; induced in azole-resistant strain that overexpresses MDR1; protein present in exponential and stationary growth phase yeast cultures; Spider biofilm induced ||	1	0.30	-1.62	-1.50	-1.17	0.71	-0.23	0.08	-0.33
992	|| orf19.5392 || NGT1 ||  || N-acetylglucosamine (GlcNAc)-specific transporter; role in GlcNAc (but not serum) induced hyphal growth; localizes to plasma membrane; induced by GlcNAc, macrophage engulfment; 12 transmembrane, major facilitator superfamily ||	1	0.69	-1.15	-0.90	-0.75	0.06	-0.27	0.11	-0.45
993	|| orf19.6996 || MNN14 ||  || Predicted alpha-1,3-mannosyltransferase activity with a role in protein glycosylation; Hap43-repressed; Spider biofilm induced ||	1	0.76	-0.92	-0.67	-0.69	0.62	-0.15	0.07	-0.43
994	|| orf19.6730 ||  ||  || Ortholog(s) have nucleolus localization ||	1	0.87	-0.96	-0.72	-0.84	0.52	-0.12	0.08	-0.76
995	|| orf19.1633 || UTP4 ||  || Putative U3 snoRNA-associated protein; Hap43-induced; physically interacts with TAP-tagged Nop1; Spider biofilm induced ||	1	0.51	-1.04	-1.03	-0.82	0.41	0.17	0.08	-0.66
996	|| orf19.7618 ||  ||  || Putative nucleolar protein with a predicted role in pre-18S rRNA processing; Plc1p-regulated; Spider biofilm induced ||	1	0.80	-0.87	-1.26	-0.76	0.36	0.26	-0.31	-0.62
997	|| orf19.4563 ||  ||  || Protein of unknown function; repressed by prostaglandins; Hap43-induced, Spider biofilm induced ||	1	0.08	-0.76	-0.96	-0.30	0.06	0.60	-1.02	-0.75
998	|| orf19.5207 ||  ||  || Predicted diphthamide biosynthesis protein; Spider biofilm induced ||	1	0.28	-0.71	-1.47	-1.08	0.12	0.14	-1.96	-2.18
999	|| orf19.4697 || MDN1 ||  || Putative midasin, a very large dynein-related AAA-type ATPase; induced during the mating process ||	1	0.48	0.18	-0.85	-1.88	0.08	0.13	-0.37	-0.98
1000	|| orf19.3894 ||  ||  || Putative inositol oxygenase; mutation confers hypersensitivity to toxic ergosterol analog; Spider biofilm induced ||	1	-0.09	-0.13	-0.87	-0.78	-0.05	0.17	-0.15	-0.23
1001	|| orf19.946 || MET14 ||  || Putative adenylylsulfate kinase; predicted role in sulfur metabolism; possibly adherence-induced; protein present in exponential and stationary growth phase yeast; F-12/CO2 biofilm induced ||	1	-0.19	-0.25	-0.71	-0.87	-0.12	-0.07	-0.06	-0.23
1002	|| orf19.5025 || MET3 ||  || ATP sulfurlyase; sulfate assimilation; repressed by Met, Cys, Sfu1, or in fluconazole-resistant isolate; Hog1, caspofungin, white phase-induced; induced on biofilm formation, even in presence of Met and Cys; Spider, F-12/CO2 biofilm induced ||	1	0.46	-0.15	-1.43	-1.21	0.11	-0.38	0.36	-0.26
1003	|| orf19.2319 ||  ||  || Putative nucleolar protein with a predicted role in pre-rRNA processing; Hap43-induced gene; repressed in core stress response ||	1	0.51	-0.06	-0.90	-1.16	0.98	-0.09	0.33	-0.73
1004	|| orf19.1772 ||  ||  || Ortholog(s) have mitochondrion localization ||	1	0.82	0.14	-0.75	-0.38	0.76	0.26	-0.75	-0.99
1005	|| orf19.3831 ||  ||  || Ortholog(s) have telomerase inhibitor activity, role in box C/D snoRNA 3'-end processing, negative regulation of telomere maintenance via telomerase and nucleolus, nucleoplasm localization ||	1	0.77	0.21	-0.12	-0.49	0.62	-0.06	-0.68	-0.63
1006	|| orf19.48 || RPM2 ||  || Mitochondrial RNase P subunit; roles in nuclear transcription, cytoplasmic and mitochondrial RNA processing, mitochondrial translation; virulence-group-correlated expression; likely essential (UAU1 method); rat catheter biofilm induced ||	1	0.89	-0.22	-0.02	-0.34	0.44	-0.55	-1.15	-1.24
1007	|| orf19.5128 ||  ||  || Predicted ORF from Assembly 19; merged with orf19.5126 in Assembly 20 ||	1	-0.01	0.13	-0.12	0.27	0.08	0.03	-0.82	-0.74
1008	|| orf19.1179 ||  ||  || Protein of unknown function; induced in high iron; possibly subject to Kex2 processing; Hap43-repressed ||	1	1.29	-1.10	-0.63	-0.71	1.28	-0.65	1.00	-0.30