GWEIGHT Opaque cells (CAY2903) in LP Replicate 1 Opaque cells (CAY2903) in LP Replicate 2 Opaque cells (CAY2903) in LP Replicate 3 Opaque cells (CAY2903) in LP Replicate 4 White cells (RBY717) in LP Replicate 1 White cells (RBY717) in LP Replicate 2 Opaque cells (CAY2903) in SOR Replicate 1 Opaque cells (CAY2903) in SOR Replicate 2 Opaque cells (CAY2903) in SOR Replicate 3 Opaque cells (CAY2903) in SOR Replicate 4 White cells (RBY717) in SOR Replicate 1 White cells (RBY717) in SOR Replicate 2 Opaque cells (CAY2903) in SCD Replicate 1 Opaque cells (CAY2903) in SCD Replicate 2 White cells (RBY717) in SCD Replicate 1 White cells (RBY717) in SCD Replicate 2
EWEIGHT 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1
0 || orf19.7073 || || || Ortholog of S. cerevisiae : YCL002C, C. glabrata CBS138 : CAGL0B04719g, C. dubliniensis CD36 : Cd36_70180, C. parapsilosis CDC317 : CPAR2_805360 and Candida tenuis NRRL Y-1498 : cten_CGOB_00114 || 1 -0.24 -0.59 0.15 0.26 -0.19 0.03 -0.14 0.09 0.03 -0.56 -0.18 0.40 -0.30 0.54 -0.00 0.28
1 || orf19.3261 || ATO9 || || Putative fungal-specific transmembrane protein || 1 0.25 -1.02 -0.04 -0.07 0.15 0.32 0.65 -1.10 0.31 0.55 -0.62 0.43 -0.12
2 || orf19.2991 || HOL1 || || Putative MFS transporter; regulated by Nrg1; macrophage/pseudohyphal-repressed; induced by alpha pheromone in SpiderM medium; possibly an essential gene, disruptants not obtained by UAU1 method || 1 0.17 -1.61 0.18 2.10 -0.12 -0.03 -0.94 0.09 -0.54 0.79 -0.46 0.71 0.53 2.75
3 || orf19.5523 || || || Ortholog of C. dubliniensis CD36 : Cd36_62780, C. parapsilosis CDC317 : CPAR2_601690, Candida tenuis NRRL Y-1498 : CANTEDRAFT_113271 and Debaryomyces hansenii CBS767 : DEHA2A06644g || 1 -0.32 -0.38 0.34 0.47 -0.25 0.50 0.34 -0.03 0.60 -0.26 0.16 0.27 -0.06 0.40 -0.12 0.84
4 || orf19.7297 || || || Putative cystathionine gamma-synthase; decreased levels in stationary phase cultures; Hog1p-induced; Gcn4p-regulated || 1 -0.09 -0.22 -0.00 0.06 -0.92 0.44 0.58 -0.26 0.42 -0.78 0.73 0.74 -0.68 0.01 0.08 0.93
5 || orf19.4370 || || || Protein of unknown function; induced by nitric oxide; oxidative stress-induced via Cap1; fungal-specific (no human or murine homolog) || 1 0.05 0.01 0.29 0.86 -0.56 -0.22 0.12 -0.11 -0.18 -0.56 1.09 0.86 -0.26 -0.05 0.53 0.34
6 || orf19.3307 || || || Flavin-containing monooxygenase; catalyzes oxidation of biological thiols to maintain the ER redox buffer ratio for correct folding of disulfide-bonded proteins; Spider biofilm repressed || 1 -0.03 0.07 0.17 0.33 0.07 -0.25 -0.11 -0.07 0.43 -0.30 0.47 0.65 -0.42 0.14 -0.05 0.57
7 || orf19.5644 || || || Ortholog(s) have role in ascospore wall assembly, spore membrane bending pathway and cytoplasm, prospore membrane localization || 1 0.24 0.08 0.39 0.40 -0.23 -0.49 -0.07 0.07 0.37 -0.43 0.12 0.50 -0.06 -0.30 -0.01 0.49
8 || orf19.6164 || || || Ortholog of Candida albicans WO-1 : CAWG_02424 || 1 0.56 -0.49 0.36 1.20 0.23 -0.54 0.44 0.44 0.95 -0.00 0.10 0.17 -0.38 0.63 -0.35 0.82
9 || orf19.7464 || || || Putative subtilisin-family protease; mutation confers hypersensitivity to toxic ergosterol analog || 1 0.30 -0.40 0.09 0.73 -0.15 -0.02 -0.02 0.23 -0.15 -0.30 -0.37 -0.02 -0.52 -0.17 -0.16 0.47
10 || orf19.3320 || || || Dubious open reading frame || 1 0.04 -0.22 -0.09 -0.26 -0.36 -0.13 -0.18 0.58 0.07 0.72 -0.20 -0.06 -0.03 0.33 -0.12 0.44
11 || orf19.218 || BUD20 || || Protein similar to S. cerevisiae Bud20p, which affects bud site selection; transposon mutation affects filamentous growth || 1 0.14 -0.03 -0.54 -0.57 0.51 -0.18 0.51 0.45 0.24 -0.19 0.78 -0.25 0.91
12 || orf19.344 || || || Protein of unknown function; upregulated by fluphenazine treatment or in an azole-resistant strain that overexpresses CDR1 and CDR2; transcript possibly regulated by Tac1 || 1 -1.02 -0.68 0.00 0.29 -0.74 -0.26 0.74 0.80 0.32 0.33 0.25 -0.21 0.15 1.19 -0.45 0.74
13 || orf19.5879 || || || Has domain(s) with predicted oxidoreductase activity and role in metabolic process || 1 0.26 0.25 0.22 -0.38 -0.21 -0.57 0.45 0.55 0.64 0.33 0.61 -0.40 -0.23 0.81 -0.24 0.34
14 || orf19.6007 || || || Predicted fatty acid acyl transferase-related protein domain; repressed by prostaglandins || 1 0.15 -0.02 0.20 -0.06 -0.25 -0.26 0.12 0.13 0.34 0.12 0.11 -0.05 0.27 0.28 0.19 0.35
15 || orf19.7096 || || || Ortholog(s) have fungal-type vacuole membrane, mitochondrion localization || 1 0.03 -0.26 0.10 0.14 0.06 -0.33 -0.09 -0.15 0.26 -0.38 -0.12 0.14 0.17 -0.15 0.04 0.45
16 || orf19.3781 || || || Protein of unknown function; Hap43-repressed; Spider biofilm induced || 1 0.08 -0.07 0.32 0.08 0.20 0.27 -0.49 -0.55 0.21 -0.46 -0.14 0.36 0.38 -0.40 0.16 0.91
17 || orf19.6481 || YPS7 || || Putative aspartic-type endopeptidase with limited ability to degrade alpha pheromone; mutants show increased sensitivity to alpha pheromone || 1 0.10 0.21 0.33 -0.28 0.43 0.09 -0.49 -0.18 0.07 -0.08 0.31 0.57 0.43 0.27 -0.00 1.18
18 || orf19.4461 || || || Ortholog of Candida albicans WO-1 : CAWG_01005 || 1 -0.17 0.55 2.79 0.85 -1.94 1.27 0.71 0.26 0.22 3.55 0.56 5.60
19 || orf19.4819 || || || Protein of unknown function; transcript detected on high-resolution tiling arrays; rat catheter biofilm induced || 1 -0.06 1.01 0.17 0.19 -1.00 -1.00 0.19 1.50 -0.06 2.03 1.24 1.10 1.94
20 || orf19.4270 || MNN13 || || Predicted alpha-1,3-mannosyltransferase activity with a role in protein glycosylation; regulated by Sef1p-, Sfu1p-, and Hap43p || 1 0.01 -0.13 -0.22 0.08 0.57 0.70 0.09 0.17 0.01 -0.62 -0.04 0.38 0.46 0.67 0.70 1.15
21 || orf19.4200 || || || Ortholog of Candida albicans WO-1 : CAWG_05300 || 1 0.28 0.78 -0.68 1.06 -0.66 -0.38 -0.55 0.45 0.57 0.76 2.23 0.86 4.10
22 || orf19.2680 || || || Ortholog(s) have phospholipid-translocating ATPase activity, role in intracellular protein transport, phospholipid translocation and trans-Golgi network transport vesicle localization || 1 0.17 0.02 -0.24 -0.19 0.10 -0.05 -0.10 -0.16 -0.20 -0.23 -0.13 -0.04 0.04 0.67 0.30 0.37
23 || orf19.644 || HGT9 || || Putative glucose transporter of the major facilitator superfamily; the C. albicans glucose transporter family comprises 20 members; 12 probable membrane-spanning segments; induced at low (0.2%, compared to 2%) glucose in rich media; intron || 1 -0.19 -0.40 0.35 -0.25 -0.64 -0.30 0.02 -0.30 -0.04 -0.46 -0.26 -0.19 0.13 0.28 -0.00 1.50
24 || orf19.4179 || || || Putative adhesin-like protein || 1 -0.73 -0.16 0.43 -0.23 -0.38 -1.17 -0.16 -0.05 -0.38 -0.15 0.11 -0.44 -0.15 -0.48 2.95
25 || orf19.7609 || PGA11 || || Putative GPI-anchored protein || 1 -0.47 -0.41 0.16 -0.05 -0.31 -0.48 -0.00 -0.23 -0.16 -0.44 -0.46 0.68 -0.70 0.29 0.11 2.69
26 || orf19.5172 || LIP9 || || Secreted lipase, member of a lipase gene family whose members are expressed differentially in response to carbon source and during infection; may have a role in nutrition and/or in creating an acidic microenvironment || 1 -1.07 -0.79 -0.99 -1.13 -0.34 -0.02 0.04 -0.60 0.74 -0.05 -0.51 3.33
27 || orf19.4822 || LIP10 || || Secreted lipase, member of a lipase gene family whose members are expressed differentially in response to carbon source and during infection; may have a role in nutrition and/or in creating an acidic microenvironment || 1 -0.21 -0.30 -0.50 -0.83 0.05 -0.86 1.43 -0.08 -0.10 -0.37 -0.17 0.62 0.27 3.87
28 || orf19.3719 || || || Dubious open reading frame || 1 -0.05 -0.09 -0.07 0.10 0.13 0.51 0.22 0.09 -0.13 0.17 0.27 0.01 1.32
29 || orf19.7007 || || || Ortholog of C. dubliniensis CD36 : Cd36_70990 and Candida albicans WO-1 : CAWG_05464 || 1 -0.43 -0.14 -0.28 -0.90 0.58 -0.59 -0.15 0.41 0.43 0.31 -0.27 0.05 -0.58 0.17 0.04 3.04
30 || orf19.948 || || || Ortholog of Candida albicans WO-1 : CAWG_04435 || 1 0.50 0.05 1.27 -0.16 -0.27 0.32 -0.21 0.64 1.28 0.86 -0.76 -0.40 4.87
31 || orf19.4239 || || || Planktonic growth-induced gene || 1 -0.38 -0.18 0.16 0.18 0.68 -1.23 -0.16 -0.40 0.14 0.19 -0.06 0.50 0.20 -1.09 3.04
32 || orf19.1524 || SPR3 || || Septin; mutant has no obvious phenotype || 1 0.08 0.17 -1.20 0.15 -0.34 -0.13 0.03 -0.61 0.15 0.40 -0.09 -0.61 0.33 3.01
33 || orf19.420 || || || Protein of unknown function || 1 0.02 0.26 -0.77 -0.80 -0.03 -0.49 -0.89 -0.62 0.52 0.01 0.81 0.08 -0.74 2.09
34 || orf19.3736 || KAR4 || || Transcription factor; required for gene regulation in response to pheromones; ortholog of S. cerevisiae Kar4; role in karyogamy; opaque-specific, a-specific; induced by alpha factor || 1 -0.39 0.22 -0.88 0.10 -0.91 -0.11 -0.10 0.30 0.12 -0.48 1.24 -0.71 1.27 0.79 2.27
35 || orf19.2370 || DSL1 || || Protein similar to S. cerevisiae Dsl1p, which is a member of the t-SNARE complex of the endoplasmic reticulum || 1 0.06 0.20 -0.01 0.07 0.06 0.25 0.04 -0.12 0.02 0.04 0.48 0.53 -0.42 0.35 0.45 0.87
36 || orf19.1571 || ATO7 || || Putative fungal-specific transmembrane protein || 1 0.02 0.52 0.12 -0.25 0.73 0.18 0.05 0.13 0.30 1.05 -0.29 0.17 0.38 1.73
37 || orf19.1135 || CAS1 || || Putative transcription factor with Ku70/Ku80 beta-barrel DNA-binding motif; involved in telomerase regulation and telomere protection; mutation causes marginal increase in caspofungin sensitivity || 1 0.25 0.45 0.25 -0.16 0.09 -0.28 0.01 0.59 0.19 0.22 0.65 0.51 0.28 0.24 0.19 1.30
38 || orf19.57 || PSF2 || || Ortholog(s) have role in DNA-dependent DNA replication, cellular protein localization, double-strand break repair via break-induced replication, meiotic chromosome segregation || 1 0.50 0.07 0.08 -0.57 0.38 0.33 0.50 0.73 0.27 0.27 0.54 1.29 -0.27 0.54 -0.27 1.61
39 || orf19.866 || RAD32 || || Protein similar to S. cerevisiae protein with role in nucleotide excision repair; down-regulation associated with azole resistance; Hap43p-repressed gene || 1 0.23 0.24 0.20 -0.71 -0.16 0.25 0.35 0.11 0.60 -0.08 0.74 0.78 -0.07 0.11 -0.12 0.94
40 || orf19.2069 || SMF3 || || Putative vacuolar iron transporter; alkaline upregulated; caspofungin repressed; induced by Mnl1 under weak acid stress; Hap43-repressed || 1 0.08 -0.16 -0.04 -0.15 -0.27 -0.05 0.11 0.33 0.25 -0.34 0.58 0.38 -0.02 0.00 -0.43 1.10
41 || orf19.5841 || || || Ortholog of C. dubliniensis CD36 : Cd36_17700, C. parapsilosis CDC317 : CPAR2_212340, Candida tenuis NRRL Y-1498 : CANTEDRAFT_101113 and Debaryomyces hansenii CBS767 : DEHA2G03784g || 1 0.36 0.40 0.04 -0.33 -0.05 0.17 0.31 0.59 0.17 0.18 0.17 0.14 -0.23 -0.07 -0.06 0.58
42 || orf19.4909 || CBK1 || || Ser/Thr kinase of cell wall integrity pathway; mutants show abnormal morphology and aggregation; Mob2p associated; required for wild-type hyphal growth and transcriptional regulation of cell-wall-associated genes || 1 0.07 -0.28 0.12 -0.39 -0.43 -0.64 0.38 0.54 0.14 0.52 0.37 0.41 0.37 0.51 -0.21 0.62
43 || orf19.5578 || || || Ortholog of C. dubliniensis CD36 : Cd36_63050 and Candida albicans WO-1 : CAWG_05094 || 1 -0.55 -0.21 0.40 -0.80 -0.02 -0.80 0.04 0.02 0.24 0.34 0.55 0.49 0.26 0.57 -0.50 0.70
44 || orf19.1988 || CDC45 || || Putative DNA replication initiation factor; transcriptionally regulated by interaction with macrophage || 1 -0.24 -0.19 -0.06 -0.84 -0.36 -0.69 0.02 0.20 0.30 0.18 1.03 0.41 0.55 0.63 -0.31 1.16
45 || orf19.4703 || || || Protein with similarity to mutator-like element (MULE) transposase || 1 -0.01 0.03 -0.28 -0.47 -0.38 -0.16 0.09 0.30 0.64 0.08 0.61 0.42 0.37 0.65 -0.65 1.20
46 || orf19.2909 || ERG26 || || C-3 sterol dehydrogenase, catalyzes the 2nd of 3 steps required to remove 2 C-4 methyl groups from an intermediate in ergosterol biosynthesis; amphotericin B, caspofungin repressed; Spider biofilm repressed || 1 0.28 0.02 -0.47 -0.33 -0.73 -0.51 0.29 0.45 0.15 0.09 0.35 0.25 -0.18 0.61 -0.20 0.88
47 || orf19.5376 || || || Ortholog of S. cerevisiae Elm1; a serine/threonine protein kinase that regulates cellular morphogenesis, septin behavior, and cytokinesis in S. cerevisiae; possibly an essential gene, disruptants not obtained by UAU1 method || 1 -0.01 -0.24 -0.46 -0.33 -0.07 -0.38 -0.00 -0.09 0.04 0.28 0.09 0.24 -0.01 0.02 -0.19 0.46
48 || orf19.5722 || || || Ortholog(s) have DNA binding activity || 1 0.17 0.14 -0.74 -0.64 -0.47 -0.26 -0.18 -0.23 -0.18 0.60 0.76 0.84 0.21 0.11 -0.52 0.52
49 || orf19.5523 || || || Ortholog of C. dubliniensis CD36 : Cd36_62780, C. parapsilosis CDC317 : CPAR2_601690, Candida tenuis NRRL Y-1498 : CANTEDRAFT_113271 and Debaryomyces hansenii CBS767 : DEHA2A06644g || 1 -0.32 -0.50 -0.16 -0.45 -0.04 0.24 0.03 0.28 -0.07 -0.25 1.20 0.26 -0.50 -0.18 0.56
50 || orf19.5523 || || || Ortholog of C. dubliniensis CD36 : Cd36_62780, C. parapsilosis CDC317 : CPAR2_601690, Candida tenuis NRRL Y-1498 : CANTEDRAFT_113271 and Debaryomyces hansenii CBS767 : DEHA2A06644g || 1 -0.23 -0.28 -0.25 -0.31 -0.11 -0.20 0.25 0.37 -0.31 -0.20 1.06 0.38 -0.41 0.63 -0.68 0.65
51 || orf19.5485 || MEC3 || || Putative DNA damage and meiotic pachytene checkpoint protein; increased transcription is observed upon benomyl treatment || 1 -0.03 -0.10 -0.16 -0.12 0.22 -0.28 0.25 0.57 0.39 -0.06 0.66 0.05 -0.47 0.80 -0.31 0.41
52 || orf19.5388 || SWD1 || || Ortholog(s) have histone methyltransferase activity (H3-K4 specific) activity, role in chromatin silencing at telomere, histone H3-K4 methylation, telomere maintenance and Set1C/COMPASS complex, cytosol localization || 1 0.05 -0.24 0.04 -0.14 -0.15 -0.22 -0.23 0.23 0.01 -0.06 0.39 0.20 -0.34 0.69 -0.96 0.69
53 || orf19.1116 || || || Protein of unknown function; planktonic growth-induced gene || 1 -0.03 -0.00 0.09 -0.26 -0.10 0.05 0.37 -0.05 -0.27 -0.19 0.70 -0.30 -0.38 0.32 -0.66 0.76
54 || orf19.1105 || || || Ortholog of C. parapsilosis CDC317 : CPAR2_302980, C. dubliniensis CD36 : Cd36_53630, Pichia stipitis Pignal : PICST_32155 and Candida orthopsilosis Co 90-125 : CORT_0E05120 || 1 -0.02 0.59 -0.97 -0.23 -0.05 -0.23 0.30 0.24 0.07 0.02 0.74 -0.24 -0.04 1.00 -0.50 0.69
55 || orf19.7480 || || || Putative protein of unknown function; transcript is upregulated in clinical isolates from HIV+ patients with oral candidiasis || 1 0.87 0.07 -0.67 0.02 -0.17 0.18 0.02 -0.24 0.18 -0.09 0.14 0.06 -0.18 0.37 -0.14 0.61
56 || orf19.3404 || || || Protein of unknown function; transcription repressed by fluphenazine treatment || 1 0.59 0.63 -0.70 0.90 -0.40 -0.75 -0.51 -1.46 0.10 -0.16 0.26 0.13 0.00 0.30 0.92
57 || orf19.6833.2 || || || Ortholog of Candida albicans WO-1 : CAWG_00951 || 1 0.06 0.02 -1.13 0.96 -0.11 0.64 -0.31 -0.23 -0.52 -0.33 -0.69 0.12 0.31 1.02
58 || orf19.2832 || INN1 || || Protein with similarity to S. cerevisiae Inn1p, which is an essential protein of the contractile actomyosin ring required for ingression of the plasma membrane into the bud neck during cytokinesis; contains a C2 membrane targeting domain || 1 0.33 0.34 -0.09 0.13 0.00 -0.39 1.08 -0.21 -0.22 -0.48 0.20 -0.23 0.18 0.92 0.25 0.58
59 || orf19.4151 || SPO1 || || Protein similar to phospholipase B; fungal-specific (no human or murine homolog) || 1 0.65 0.80 -0.52 -0.06 -0.50 0.81 -0.46 0.50 0.03 0.54 1.06 1.03
60 || orf19.5264 || || || Dubious open reading frame || 1 -0.17 1.27 -0.03 -0.70 1.36 -1.00 0.96 0.30 -0.16 -0.21 0.94 -0.40 0.47
61 || orf19.4337 || || || Predicted membrane transporter; monocarboxylate porter (MCP) family, major facilitator superfamily (MFS); Spider biofilm induced; rat catheter biofilm repressed || 1 -0.00 0.10 -0.12 0.52 -0.18 -0.14 0.55 0.04 0.40 -0.29 -0.02 0.97 0.66 0.66 0.15 0.00
62 || orf19.1863 || || || Has domain(s) with predicted Rho guanyl-nucleotide exchange factor activity, role in regulation of Rho protein signal transduction and intracellular localization || 1 0.47 0.14 0.27 0.19 -0.17 -0.03 0.71 -0.01 1.07 -0.36 -0.00 1.88 0.72 0.23 1.50 0.22
63 || orf19.5556 || || || Ortholog of Candida albicans WO-1 : CAWG_05078 || 1 -0.36 0.00 -0.19 -0.42 0.23 0.21 -0.04 0.31 -0.48 0.02 0.77 0.59 0.98 0.27
64 || orf19.906 || ROM2 || || Putative GDP/GTP exchange factor; possibly an essential gene, disruptants not obtained by UAU1 method; Spider biofilm induced || 1 -0.33 -0.25 -0.28 -0.09 -0.30 -0.19 -0.37 -0.19 0.19 -0.05 0.11 0.34 0.19 0.31 0.35 0.19
65 || orf19.4819 || || || Protein of unknown function; transcript detected on high-resolution tiling arrays; rat catheter biofilm induced || 1 -0.42 0.44 -0.98 -0.27 -1.06 -1.18 -0.56 0.11 -0.22 2.67 0.19 0.69 0.93
66 || orf19.5377 || HOS2 || || Putative histone deacetylase; mutations affect filamentous growth; genetic evidence suggests that Set3p and Hos2p function together as a complex involved in regulation of white-opaque switching, morphogenesis, and virulence || 1 -0.13 -0.08 0.19 -0.11 -0.16 0.10 -0.11 -0.02 0.23 0.22 -0.06 0.74 0.03 0.03 0.35 0.46
67 || orf19.1493 || RAD7 || || Protein similar to S. cerevisiae Rad7p, which is a subunit of the Nucleotide Excision Repair Factor 4; induced under hydroxyurea treatment || 1 -0.02 0.04 0.27 0.02 -0.11 -0.08 -0.14 -0.02 0.29 0.06 0.11 0.55 0.02 0.22 0.23 0.47
68 || orf19.2911 || SEC3 || || Predicted subunit of the exocyst complex, involved in exocytosis; required for hyphal growth after the first septin ring formation; interacts with septins Cdc3p, Cdc10p, and Cdc11p; localizes to a crescent on the surface of the hyphal tip || 1 0.00 0.01 0.20 0.19 0.10 -0.12 -0.18 -0.02 -0.17 0.12 0.14 0.41 -0.04 0.59 0.30 0.49
69 || orf19.1530 || || || Protein of unknown function || 1 0.31 0.19 0.04 1.26 -2.07 -0.45 -0.22 -1.23 0.02 0.46 2.91 0.07 1.04
70 || orf19.5495 || || || Putative RNA-binding protein; induced by alpha pheromone in SpiderM medium || 1 0.37 0.32 -0.11 0.34 0.34 0.04 -0.50 -0.40 -0.37 0.22 0.37 0.77 0.01 -0.23 0.57 -0.12
71 || orf19.4954 || || || Ortholog(s) have endoplasmic reticulum, integral to membrane localization || 1 0.01 0.11 0.31 0.52 0.07 -0.18 -0.43 -0.25 -0.37 0.05 0.23 0.41 0.18 -0.05 0.25 -0.06
72 || orf19.7173 || || || Ortholog of C. parapsilosis CDC317 : CPAR2_702310, C. dubliniensis CD36 : Cd36_73730, Lodderomyces elongisporus NRLL YB-4239 : LELG_04029 and Candida orthopsilosis Co 90-125 : CORT_0G02490 || 1 0.14 0.01 0.28 0.44 0.44 0.04 -0.09 0.22 -0.05 0.05 0.49 1.00 0.47 -0.01 0.23 0.00
73 || orf19.3049 || || || Ortholog(s) have protein kinase activity, role in activation of bipolar cell growth, ascospore wall assembly, protein phosphorylation and cell division site, cytosol, nucleus, prospore membrane localization || 1 0.84 0.21 -0.12 -0.67 0.43 0.27 -0.46 -0.64 -0.56 -0.18 -0.01 4.71 -0.43 0.53 -0.71
74 || orf19.2505 || || || Ortholog of Candida albicans WO-1 : CAWG_02437 || 1 -1.00 0.05 0.28 0.66 -0.64 -1.02 0.23 0.30 -0.08 3.23 -0.54 -0.55 0.31 -0.17
75 || orf19.5264 || || || Dubious open reading frame || 1 -0.20 0.08 -0.67 0.28 -0.28 -0.29 0.73 0.67 0.33 0.09 -0.71 2.43 -0.31 0.35 -0.54
76 || orf19.5717 || || || Ortholog of Candida albicans WO-1 : CAWG_05019 || 1 0.64 -0.18 -0.51 -0.80 -0.55 -0.53 0.39 0.57 0.09 -0.05 -0.01 1.85 -0.49 0.26 0.53 0.30
77 || orf19.1215 || || || Ortholog of C. dubliniensis CD36 : Cd36_64550, Candida tropicalis MYA-3404 : CTRG_02747 and Candida albicans WO-1 : CAWG_04972 || 1 0.49 -0.61 -0.06 -0.31 -0.11 -0.20 -0.23 1.34 0.28 0.22 -0.06 1.74 -0.72 0.48 -0.21
78 || orf19.687 || || || Ortholog of C. dubliniensis CD36 : Cd36_62090, C. parapsilosis CDC317 : CPAR2_602150, Candida tenuis NRRL Y-1498 : CANTEDRAFT_112751 and Debaryomyces hansenii CBS767 : DEHA2F11814g || 1 0.11 0.03 -0.12 -0.09 0.69 -0.67 -0.01 0.44 -0.27 0.69 0.03 0.87 -0.31 -0.44 0.04 0.45
79 || orf19.6662 || || || Putative coenzyme Q (ubiquinone) binding protein; transcript is upregulated in clinical isolates from HIV+ patients with oral candidiasis || 1 0.32 -0.30 -0.38 -0.06 0.12 -0.67 0.07 0.25 0.13 0.56 0.05 0.63 0.28 0.27 0.05 0.19
80 || orf19.4151 || SPO1 || || Protein similar to phospholipase B; fungal-specific (no human or murine homolog) || 1 0.58 -0.40 -1.81 0.21 -0.67 -0.35 1.99 -0.26 1.22 0.38 0.77 0.38 0.70
81 || orf19.5844 || || || Ortholog(s) have role in meiotic DNA recombinase assembly, reciprocal meiotic recombination and condensed nuclear chromosome localization || 1 0.13 0.31 -0.40 0.33 0.06 -0.50 0.61 -0.30 0.10 0.49 -0.02 0.25 -0.00 0.34
82 || orf19.6482 || || || Protein of unknown function; induced by nitric oxide independent of Yhb1p; regulated by Sef1, Sfu1, and Hap43; rat catheter biofilm induced || 1 -0.24 0.07 -0.99 0.46 0.16 -0.66 1.77 0.49 0.36 2.13 0.13 0.98 0.85
83 || orf19.2784 || || || Ortholog of C. dubliniensis CD36 : Cd36_07090, Candida tenuis NRRL Y-1498 : cten_CGOB_00237, Debaryomyces hansenii CBS767 : DEHA2F25542g and Pichia stipitis Pignal : psti_CGOB_00186 || 1 0.28 0.09 -0.53 -0.75 0.12 -0.28 -0.20 0.68 -0.37 0.42 0.51 0.68 0.01 0.22 0.66 0.67
84 || orf19.5734 || POP2 || || Component of the Ccr4-Pop2 mRNA deadenylase; heterozygous null mutant exhibits resistance to parnafungin and cordycepin in the C. albicans fitness test || 1 0.87 -0.19 -0.18 -0.05 -0.31 -0.22 0.08 0.20 0.32 0.28 0.26 0.62 0.17 0.19 0.31 0.01
85 || orf19.3903 || MRV3 || || Ortholog of Candida albicans WO-1 : CAWG_04793 || 1 -0.13 -0.68 0.35 0.28 -0.20 -0.32 1.43 1.61 0.64 2.27 -0.29 -0.57
86 || orf19.6283 || || || Ortholog(s) have mitochondrion localization || 1 -0.04 -0.09 0.04 -0.01 -0.05 -0.13 -0.02 0.28 0.51 0.51 -0.02 0.39 0.09 0.32 -0.07 -0.10
87 || orf19.2211 || || || Ortholog of C. dubliniensis CD36 : Cd36_21990, C. parapsilosis CDC317 : CPAR2_103660, Debaryomyces hansenii CBS767 : DEHA2F19756g and Pichia stipitis Pignal : PICST_61375 || 1 -0.00 1.14 -0.72 -0.82 -0.62 -0.52 -0.05 1.43 1.21 0.53 1.02 0.69 0.35
88 || orf19.3284 || || || Ortholog of Candida albicans WO-1 : CAWG_01431 || 1 1.15 0.64 -0.44 -0.20 -0.24 -0.19 3.07 2.31 0.93 1.50 0.70 0.12 0.44
89 || orf19.6533 || MSK1 || || Putative mitochondrial lysine-tRNA synthetase; flucytosine repressed || 1 0.06 0.27 -0.06 -0.29 0.17 -0.12 0.13 0.09 0.99 0.28 0.12 0.31 0.12 -0.24 -0.06 0.30
90 || orf19.450 || || || Protein of unknown function || 1 -0.05 -0.69 -0.04 -0.60 -0.56 0.63 -0.33 -0.32 0.53 1.55 0.07 1.00 -0.76 1.29 0.93
91 || orf19.4142 || || || Putative transporter; decreased transcription is observed upon fluphenazine treatment || 1 0.02 -0.35 -0.10 -0.34 -0.03 0.10 0.14 0.26 -0.11 0.65 -0.14 0.67 -0.14 0.25 0.74 0.26
92 || orf19.6502 || || || Short-chain dehydrogenase/reductase; upregulation correlates with clinical development of fluconazole resistance || 1 -0.04 0.05 0.33 -0.73 -0.35 -0.01 0.10 0.31 -0.61 1.29 -0.44 0.31 0.00 0.61 0.57
93 || orf19.3284 || || || Ortholog of Candida albicans WO-1 : CAWG_01431 || 1 0.23 -0.09 0.41 -2.36 -0.71 1.66 0.12 -0.01 0.15 0.37 -0.09 -1.14
94 || orf19.322 || || || Ortholog of Candida albicans WO-1 : CAWG_02670 || 1 0.35 0.23 0.23 -1.94 -0.25 0.80 0.28 0.49 -0.08 -0.18 2.98 -0.13 -0.59 0.40 0.58
95 || orf19.7072 || PEL1 || || Predicted enzyme of mitochondrial phospholipid biosynthesis; rat catheter and flow model biofilm induced || 1 -0.16 -0.11 -0.12 -0.22 0.03 0.10 0.16 0.02 -0.48 0.13 0.26 0.67 0.05 -0.05 0.03 0.23
96 || orf19.1827 || || || Protein of unknown function; flow model biofilm induced; induced by alpha pheromone in SpiderM medium || 1 -0.01 0.01 -0.34 -0.25 1.21 0.01 0.40 -1.29 -0.02 0.87 0.95 0.21 -0.86 0.30 0.48
97 || orf19.7348 || || || Ortholog of Candida albicans WO-1 : CAWG_02878 || 1 0.12 -0.07 0.02 -0.24 -0.28 0.19 -0.14 0.38 -0.36 -0.28 0.02 0.51 0.13 -0.35 -0.04 -0.04
98 || orf19.6181 || || || Ortholog of Candida albicans WO-1 : CAWG_03093 || 1 0.13 0.53 -0.34 -1.05 -0.43 0.06 -0.72 0.59 0.09 0.31 0.94 -0.15 -1.07 -0.00 0.86
99 || orf19.6390 || || || Protein of unknown function; Spider biofilm induced || 1 0.54 0.19 0.49 -0.18 -1.41 0.39 -0.05 -0.47 0.30 -0.12 1.52 0.53 -1.99 0.30 0.97
100 || orf19.1744 || HEM4 || || Putative uroporphyrinogen III synthase; induced in high iron or elevated CO2; alkaline, Hap43-repressed || 1 0.28 0.24 -0.14 -0.57 -0.31 0.23 0.54 0.11 -0.13 0.20 0.52 0.46 -1.03 -0.54 0.30 0.83
101 || orf19.1744 || HEM4 || || Putative uroporphyrinogen III synthase; induced in high iron or elevated CO2; alkaline, Hap43-repressed || 1 0.54 0.34 -0.32 -0.39 -0.32 -0.07 0.59 0.29 -0.01 0.21 0.73 0.36 -0.88 -0.75 0.30 0.58
102 || orf19.4747 || HEM14 || || Putative protoporphyrinogen oxidase; involved in heme biosynthesis; predicted Kex2p substrate; iron regulated transcript; Yfh1-induced; Hap43-repressed; rat catheter biofilm repressed || 1 0.31 0.26 -0.69 -1.06 -0.26 -0.25 0.64 0.90 0.82 -0.49 1.28 0.86 -1.31 -1.29 -0.91 0.75
103 || orf19.3868 || || || Dubious open reading frame || 1 0.15 -0.01 -0.29 -0.27 -0.04 -0.62 -0.13 0.30 -0.15 -0.19 0.52 0.14 -0.38 -0.50 -0.06 0.50
104 || orf19.5239 || || || Predicted alanine-tRNA ligase; oxidative stress-induced via Cap1 || 1 0.48 -0.31 -0.86 -0.23 -0.47 -0.53 0.22 -0.20 0.15 -0.37 0.66 0.80 -0.56 -0.96 0.12 0.63
105 || orf19.1864 || || || Ortholog(s) have role in ribosome-associated ubiquitin-dependent protein catabolic process and RQC complex, cytosol, cytosolic large ribosomal subunit localization || 1 0.07 -0.12 -0.59 -0.51 -0.19 -0.42 -0.10 0.07 0.64 0.34 0.42 0.40 -0.40 -0.78 0.22 0.39
106 || orf19.3863 || || || Ortholog of C. dubliniensis CD36 : Cd36_31580, C. parapsilosis CDC317 : CPAR2_205000, Debaryomyces hansenii CBS767 : DEHA2G10846g and Pichia stipitis Pignal : PICST_32988 || 1 -0.07 0.09 -0.03 -0.85 0.04 0.31 -0.31 -0.26 0.50 0.39 0.02 0.81 0.42 -0.31 -0.36 0.83
107 || orf19.5490 || || || Predicted ORF in Assemblies 19, 20 and 21; merged with orf19.5489 in Assembly 21 || 1 -0.25 -0.17 0.25 -0.97 0.01 0.32 -0.35 -0.43 0.46 0.51 -0.04 0.28 -0.20 -0.19 -0.86 0.13
108 || orf19.2868 || || || Protein of unknown function; induced by alpha pheromone in SpiderM medium || 1 -0.30 -0.24 0.63 -0.74 -0.13 -0.09 -0.13 -0.33 0.52 0.08 -0.02 0.45 -0.03 -0.22 -0.49 0.30
109 || orf19.2265 || || || Ortholog(s) have role in positive regulation of transcription from RNA polymerase II promoter in response to amino acid starvation and SWI/SNF complex, cytosol localization || 1 -0.11 0.00 0.65 -0.31 -0.20 -0.06 -0.06 0.04 0.00 -0.11 0.01 0.53 0.17 0.16 -0.09 0.23
110 || orf19.2326 || || || Ortholog(s) have role in chromatin silencing at silent mating-type cassette, double-strand break repair via homologous recombination, intra-S DNA damage checkpoint, mitotic sister chromatid cohesion and nucleus localization || 1 -0.42 -0.28 0.48 -0.29 0.09 0.03 -0.06 -0.10 0.34 -0.04 0.01 0.40 0.19 0.26 -0.16 0.36
111 || orf19.5257 || LCB4 || || Putative sphingosine kinase; Tac1p-regulated expression; rat catheter biofilm induced || 1 -0.19 -0.04 0.40 0.01 0.10 -0.30 -0.37 -0.11 0.51 -0.28 0.19 0.35 0.04 0.33 -0.39 0.25
112 || orf19.3685 || PSY2 || || Putative protein phosphatase PP4 complex subunit; macrophage-induced gene || 1 -0.25 0.00 0.01 -0.22 0.06 -0.03 -0.27 -0.32 0.31 0.05 -0.10 0.35 0.31 0.57 -0.40 0.34
113 || orf19.1741 || DIT1 || || Ortholog(s) have catalytic activity and role in ascospore wall assembly || 1 -0.32 -0.49 0.42 0.21 -0.17 -0.44 0.36 -0.08 -0.33 0.19 0.60 0.23 -0.92 0.25
114 || orf19.6094 || VPS53 || || Ortholog(s) have role in Golgi to vacuole transport, retrograde transport, endosome to Golgi and GARP complex localization || 1 -0.48 -0.16 0.12 -0.02 -0.12 0.06 -0.31 -0.33 0.20 -0.08 -0.06 0.00 0.12 0.10 -0.34 0.32
115 || orf19.7516 || || || Putative glycoside hydrolase; Hap43-induced gene || 1 -0.57 0.03 0.52 0.32 0.17 0.47 -0.53 -0.01 0.11 0.07 -0.16 0.45 -0.01 -0.19 -0.52 0.42
116 || orf19.5984 || || || Putative protein of unknown function; homozygous transposon insertion causes decreased colony wrinkling under filamentous growth-inducing conditions, but does not block true hyphal formation in liquid media || 1 -0.41 0.16 0.49 0.20 0.34 0.00 -0.38 -0.48 0.59 0.38 -0.55 0.41 0.52 0.13 -0.04 0.43
117 || orf19.7558 || YTA6 || || Protein similar to S. cerevisiae Yta6p ATPase but ortholog of S. cervisiae Sap1; transposon mutation affects filamentous growth; induced by Mnl1 under weak acid stress || 1 -0.04 -0.01 0.29 0.09 0.14 0.22 -0.18 -0.43 0.47 0.11 -0.28 0.46 0.26 -0.26 0.09 0.06
118 || orf19.2547 || || || Has domain(s) with predicted RNA binding, ribonuclease activity || 1 -0.35 -0.28 0.47 0.08 -0.05 0.10 -0.66 -0.69 0.20 0.41 -0.56 0.49 0.14 -0.17 -0.32 -0.39
119 || orf19.5242 || CDC6 || || Putative ATP-binding protein with a predicted role in DNA replication; member of conserved Mcm1p regulon; periodic mRNA expression, peak at cell-cycle M/G1 phase || 1 0.29 0.67 0.24 0.02 0.69 -0.03 -1.02 -1.08 0.21 0.70 -0.72 0.45 0.03 -0.79 -1.00 -0.30
120 || orf19.6267 || || || Ortholog of C. dubliniensis CD36 : Cd36_06020, C. parapsilosis CDC317 : CPAR2_803380, Candida tenuis NRRL Y-1498 : CANTEDRAFT_91858 and Pichia stipitis Pignal : PICST_30337 || 1 0.11 -1.08 1.64 1.66 -0.68 -0.85 -0.57 0.15 -0.06 -0.31 0.28 -0.32 -1.00 -0.05
121 || orf19.2343 || VPS23 || || ESCRT I protein sorting complex protein; involved in proteolytic activation of Rim101, which regulates pH response; ortholog of S. cerevisiae Stp22/Vps23 || 1 -0.19 -0.31 0.19 -0.22 0.57 0.09 -0.17 0.05 0.24 -0.06 0.11 0.33 0.04 -0.11 0.09 0.24
122 || orf19.7609 || PGA11 || || Putative GPI-anchored protein || 1 -0.15 -0.24 0.23 0.11 0.95 -0.17 -0.10 -0.46 0.33 -0.02 0.00 0.69 -0.01 -0.16
123 || orf19.4196 || || || Dubious open reading frame || 1 -0.64 -1.27 -0.09 -0.46 0.94 0.12 0.50 -0.50 -0.07 0.02 -0.11 1.05 0.23 -0.52
124 || orf19.4750 || || || Ortholog of C. dubliniensis CD36 : Cd36_08410, C. parapsilosis CDC317 : CPAR2_301700, Candida tenuis NRRL Y-1498 : cten_CGOB_00267 and Debaryomyces hansenii CBS767 : DEHA2C10560g || 1 -0.35 -0.59 0.41 -0.35 -0.11 0.27 0.25 -0.31 0.03 -0.12 -0.03 0.61 -0.17 0.33 0.29 0.33
125 || orf19.3280 || || || Ortholog of Candida albicans WO-1 : CAWG_01435 || 1 -0.56 -1.07 1.77 -0.85 -0.90 1.78 -0.28 0.48 1.33 -1.03 3.72 0.88 -0.68 0.13
126 || orf19.3885 || || || Has domain(s) with predicted N-acetyltransferase activity; highly induced during chlamydospore formation in both C. albicans and C. dubliniensis || 1 -0.27 -0.16 0.59 -0.01 -0.45 0.31 -0.31 -0.26 0.07 -0.23 -0.26 0.54 0.11 0.57 -0.43 -0.31
127 || orf19.7074 || || || Ortholog(s) have RNA polymerase II transcription factor recruiting transcription factor activity, methylated histone residue binding activity || 1 -0.40 -0.22 0.37 0.43 -0.44 0.15 -0.05 -0.02 0.02 -0.26 -0.10 0.46 -0.08 0.18 -0.10 -0.22
128 || orf19.6399 || ATS1 || || Protein required for modification of wobble nucleosides in tRNA; induced upon adherence to polystyrene; regulated by Sef1, Sfu1, and Hap43 || 1 -0.04 0.01 0.61 0.33 -0.32 0.07 -0.32 0.11 0.01 0.19 0.03 -0.04 0.29 0.10 -0.15 0.18
129 || orf19.2332 || || || Ortholog of C. parapsilosis CDC317 : CPAR2_210560, C. dubliniensis CD36 : Cd36_10180, Candida orthopsilosis Co 90-125 : CORT_0A09890 and Candida tropicalis MYA-3404 : CTRG_04072 || 1 0.41 0.03 1.12 -0.87 -0.35 -0.26 0.44 -0.13 0.11 0.56 -0.47 0.51
130 || orf19.2010 || || || Ortholog of C. dubliniensis CD36 : Cd36_16030, C. parapsilosis CDC317 : CPAR2_213800, Debaryomyces hansenii CBS767 : DEHA2A01320g and Pichia stipitis Pignal : PICST_29434 || 1 -0.31 -0.33 1.58 0.07 -0.32 -0.34 1.09 0.09 -0.04 0.43 -0.21 -0.19
131 || orf19.6133 || PIF1 || || Putative DNA helicase; decreased transcription is observed upon fluphenazine treatment || 1 -0.08 0.03 0.01 0.34 -0.10 0.11 0.01 0.35 0.11 0.52 0.16 0.04 0.02 0.11 -0.29 -0.21
132 || orf19.3653 || FAT1 || || Predicted enzyme of sphingolipid biosynthesis; upregulated in biofilm || 1 0.22 0.06 0.27 0.74 -0.28 -0.16 0.05 0.11 0.16 0.70 0.25 0.29 -0.56 0.15 -0.09 0.16
133 || orf19.3653 || FAT1 || || Predicted enzyme of sphingolipid biosynthesis; upregulated in biofilm || 1 -0.15 0.05 -0.00 0.58 -0.55 -0.41 -0.17 0.23 -0.08 0.50 0.10 0.26 -0.97 0.02 -0.27 0.36
134 || orf19.5746 || ALA1 || || Alanyl-tRNA synthetase; translational regulation generates cytoplasmic and mitochondrial forms; Gcn4p-regulated; repressed by amino acid starvation (3-AT); translation-related genes downregulated upon phagocytosis by murine macrophages || 1 -0.14 -0.34 0.03 0.34 -0.05 -0.23 0.02 0.38 0.16 0.14 0.32 0.07 -0.32 -0.14 -0.04 -0.05
135 || orf19.302 || || || Ortholog(s) have Rab guanyl-nucleotide exchange factor activity, role in ER to Golgi vesicle-mediated transport and TRAPP complex, cytosol, nucleus localization || 1 -0.22 -0.59 -0.04 0.37 0.19 -0.04 -0.04 0.21 0.49 0.29 0.42 0.61 -0.51 -0.06 -0.29 0.20
136 || orf19.3186 || || || Ortholog of Candida albicans WO-1 : CAWG_04571 || 1 0.06 0.04 0.14 0.42 -0.07 -0.14 -0.32 -0.02 -0.10 0.07 0.54 0.24 -0.26 0.35 0.06 -0.22
137 || orf19.3000 || ORC1 || || Putative origin recognition complex large subunit; essential for viability; similar to S. cerevisiae Orc1p origin recognition complex subunit || 1 0.02 -0.04 0.13 -0.16 0.08 -0.14 0.01 -0.14 0.26 0.10 0.12 -0.01 -0.12 0.06 0.11 0.02
138 || orf19.3336 || || || Ortholog of Candida albicans WO-1 : CAWG_01228 || 1 -0.25 0.06 0.15 -0.45 0.25 -0.14 0.11 -0.63 0.17 0.39 0.55 -0.12 -0.47 0.95 0.53
139 || orf19.3969 || SFL2 || || Transcription factor involved in regulation of morphogenesis; required for filamentous growth, for virulence in RHE model but not in mice; induced upon RHE infection but C. dubliniensis ortholog is not; Spider biofilm induced || 1 -0.56 -0.69 1.02 -1.57 -0.28 -0.15 0.74 -0.61 0.16 -0.56 0.96 0.17 -0.11 0.26 1.29 0.78
140 || orf19.5846 || || || Putative TFIIH and nucleotide excision repair factor 3 complex subunit; possibly an essential gene, disruptants not obtained by UAU1 method || 1 -0.55 -0.54 0.18 -0.29 -0.34 -0.14 0.24 -0.10 -0.03 -0.40 0.41 -0.17 0.06 -0.11 0.14 0.39
141 || orf19.3420 || || || Protein of unknown function; decreased expression in hyphae than in yeast || 1 -0.14 -0.16 0.22 -0.36 -0.02 -0.19 0.26 0.15 0.15 0.15 0.24 -0.06 0.09 -0.31 0.31 -0.05
142 || orf19.6807 || || || Predicted ORF in retrotransposon Tca17 with similarity to parts of the Gag-Pol region of retrotransposons; clade-associated gene expression || 1 0.31 0.89 0.74 -1.47 -0.16 -0.01 1.32 0.28 0.41 0.62 -0.50 0.41 0.71 0.19
143 || orf19.2907 || PGA42 || || Putative GPI-anchored adhesin-like protein; decreased transcription is observed in azole-resistant strains that overexpress CDR1 and CDR2 or MDR1 || 1 -0.03 0.34 0.22 -0.59 -0.03 0.23 0.21 0.11 -0.00 -0.14 0.39 0.19 0.28 -0.13 0.40 0.20
144 || orf19.7103 || || || Predicted exonuclease; Spider biofilm induced || 1 -0.05 -0.03 0.17 -0.27 0.13 0.10 0.36 0.06 0.11 -0.06 0.07 0.00 -0.07 0.10 0.06 -0.04
145 || orf19.2699 || ABP1 || || Ortholog of S. cerevisiae Abp1; actin-binding protein of the cortical actin cytoskeleton; caspofungin induced; protein only detected in stationary phase yeast-form cultures; Spider biofilm repressed || 1 -0.06 -0.08 0.16 -0.00 0.09 0.05 0.54 0.36 0.44 0.00 0.19 0.19 -0.21 0.05 0.04 -0.14
146 || orf19.2337 || ALP1 || || Cystine transporter; present in pathogenic yeasts (no human or murine homolog); Spider biofilm induced || 1 -0.08 -0.07 0.33 0.26 -0.13 0.13 0.34 0.32 0.16 0.03 0.19 0.53 -0.17 0.46 0.12 -0.35
147 || orf19.552 || || || Ortholog of a S. cerevisiae Atg22; a vacuolar integral membrane protein required for efflux of amino acids during autophagic body breakdown in the vacuole; possibly an essential gene, disruptants not obtained by UAU1 method || 1 -0.29 -0.76 -0.20 -0.05 0.65 0.05 1.24 0.93 -0.32 -0.10 0.47 -0.25 0.29 0.11 -0.58
148 || orf19.3719 || || || Dubious open reading frame || 1 0.28 -0.47 0.04 -0.29 -0.42 -0.20 0.54 0.85 -0.28 -0.16 -0.23 -0.07 -0.30 -0.07 0.46 0.15
149 || orf19.1863 || || || Has domain(s) with predicted Rho guanyl-nucleotide exchange factor activity, role in regulation of Rho protein signal transduction and intracellular localization || 1 0.11 0.07 -0.15 -0.31 0.26 -0.16 0.19 0.65 -0.01 -0.21 -0.05 0.01 -0.04 -1.02 1.03 0.45
150 || orf19.2916 || || || Ortholog of C. dubliniensis CD36 : Cd36_45740, C. parapsilosis CDC317 : CPAR2_401900, Candida tenuis NRRL Y-1498 : CANTEDRAFT_116046 and Pichia stipitis Pignal : PICST_28890 || 1 0.34 -0.10 0.06 -0.39 0.43 -0.31 0.02 0.38 -0.44 -0.31 -0.27 0.82 0.00 -0.33 0.71 0.14
151 || orf19.3638 || PGA46 || || Putative GPI-anchored protein; secreted; fluconazole-induced || 1 0.46 -0.19 0.50 0.14 -0.05 -0.32 0.08 0.39 -0.37 -0.32 -0.26 0.24 -0.26 -0.27 0.40 -0.02
152 || orf19.7299.1 || || || Ortholog of Candida albicans WO-1 : CAWG_02179 || 1 0.44 0.15 1.38 -0.22 0.38 -1.18 0.31 1.31 -0.60 0.21 -0.33 -0.05 0.89 -0.12
153 || orf19.5308 || || || Protein of unknown function; induced by Rgt1 || 1 0.46 -0.09 0.83 0.50 0.20 -0.64 -0.15 0.60 -0.78 0.44 -0.26 0.15 -0.37 0.02 0.43 0.22
154 || orf19.4366 || || || Ortholog of C. dubliniensis CD36 : Cd36_28870, Candida tropicalis MYA-3404 : CTRG_00731 and Candida albicans WO-1 : CAWG_01703 || 1 0.26 0.23 0.56 0.23 -0.25 -0.12 0.04 0.23 -0.81 0.01 -0.11 -0.63 0.17 0.46 0.29
155 || orf19.4834 || || || Ortholog of C. dubliniensis CD36 : Cd36_09140, C. parapsilosis CDC317 : CPAR2_804920, Debaryomyces hansenii CBS767 : DEHA2B10516g and Pichia stipitis Pignal : PICST_30058 || 1 0.08 0.14 0.46 0.13 0.12 -0.60 -0.09 0.17 -0.97 -0.12 -0.38 0.18 -0.72 -0.01 -0.00 -0.22
156 || orf19.7609 || PGA11 || || Putative GPI-anchored protein || 1 -0.03 -0.22 0.34 -0.44 0.46 -0.59 0.26 0.16 -0.14 0.09 -0.73 0.43 -0.54 -0.13 0.26 -0.08
157 || orf19.10711 || PIKALPHA || || Putative phosphatidylinositol kinase; non-sex gene located within the MTLalpha mating-type-like locus || 1 0.20 -0.51 0.19 -0.02 0.68 -0.26 -0.28 0.39 -0.77 0.46 -0.29 0.28 -0.69 0.47 0.09 0.37
158 || orf19.7007 || || || Ortholog of C. dubliniensis CD36 : Cd36_70990 and Candida albicans WO-1 : CAWG_05464 || 1 0.02 -0.09 0.59 -0.13 0.64 0.08 -0.14 0.05 -0.15 0.35 -0.24 0.43 -0.30 0.02 0.00 0.54
159 || orf19.427 || || || Ortholog(s) have telomeric DNA binding activity and role in chromatin silencing at silent mating-type cassette, chromatin silencing at telomere, single-species biofilm formation on inanimate substrate, telomere capping || 1 0.27 0.12 0.29 0.31 0.86 0.02 -0.34 0.30 -0.38 0.41 -0.02 0.18 -0.26 -0.46 0.03 -0.20
160 || orf19.1348 || || || Ortholog of C. dubliniensis CD36 : Cd36_22500, Candida tropicalis MYA-3404 : CTRG_01825 and Candida albicans WO-1 : CAWG_05921 || 1 0.44 -0.19 0.83 -0.13 0.64 -0.10 -0.06 0.31 -0.54 0.82 0.05 0.74 -0.62 -0.72 0.44 -0.88
161 || orf19.1105.3 || || || Protein of unknown function || 1 0.10 0.50 0.35 0.61 0.28 0.32 0.33 1.03 0.30 0.55 -0.12 -0.06 0.01 -0.21 0.38 0.16
162 || orf19.1827 || || || Protein of unknown function; flow model biofilm induced; induced by alpha pheromone in SpiderM medium || 1 -0.16 0.29 0.73 0.84 0.10 0.11 0.21 0.90 0.14 0.30 -0.20 0.38 -0.32 -0.05 0.71 0.62
163 || orf19.89 || PEX7 || || Ortholog(s) have peroxisome matrix targeting signal-2 binding activity, role in fatty acid metabolic process, protein import into peroxisome matrix, docking and cytosol, nucleus, peroxisome localization || 1 -0.28 0.13 0.12 0.07 0.20 0.09 0.13 0.26 0.21 -0.05 -0.04 0.50 -0.14 -0.26 0.41 0.51
164 || orf19.4680 || || || Possile protease; mutation confers hypersensitivity to toxic ergosterol analog || 1 0.10 0.04 0.65 -0.17 0.37 0.42 0.08 0.47 0.19 0.20 0.30 0.73 -0.30 -0.48 0.47 0.38
165 || orf19.450 || || || Protein of unknown function || 1 0.17 0.30 0.68 0.38 0.25 0.56 -0.01 1.19 -0.08 -0.04 0.10 0.63 -0.08 -0.06 0.29 0.77
166 || orf19.6110 || || || Ortholog of Candida albicans WO-1 : CAWG_01361 || 1 0.19 0.25 0.81 0.03 1.50 0.32 0.25 1.93 0.24 -0.29 0.27 0.80 -0.00 -0.28 0.20 1.15
167 || orf19.2033 || PGA19 || || Putative GPI-anchored protein; macrophage-induced gene; mutants are viable || 1 -0.43 -0.42 0.55 -0.21 0.62 0.32 0.70 0.61 -0.46 0.03 -0.38 0.17 0.34
168 || orf19.354 || || || Ortholog(s) have aminopeptidase activity, role in protein processing, protein stabilization and extrinsic to mitochondrial inner membrane, nucleus localization || 1 -0.24 -0.36 0.21 -0.13 0.57 0.43 0.15 0.61 0.17 -0.13 0.34 0.64 -0.15 -0.01 0.08 0.41
169 || orf19.2469 || RAD10 || || Ortholog of S. cerevisiae Rad10, an endonuclease involved in nucleotide excision repair; mutant is extremely sensitive to UV irradiation; transcript repressed in alkaline conditions || 1 0.07 -0.28 0.43 0.10 0.38 0.28 0.30 0.39 0.17 0.08 0.13 0.40 -0.08 -0.01 0.39 0.79
170 || orf19.5764 || SKI8 || || Ortholog(s) have role in nuclear-transcribed mRNA catabolic process, 3'-5' exonucleolytic nonsense-mediated decay, nuclear-transcribed mRNA catabolic process, non-stop decay and protein complex assembly, more || 1 -0.21 -0.32 0.30 0.05 0.14 0.11 0.26 0.52 0.02 0.07 0.17 0.34 -0.10 0.09 0.43 0.26
171 || orf19.5342 || || || Ortholog(s) have cytosol, extracellular region, fungal-type vacuole, nucleus localization || 1 0.07 -0.42 0.34 0.46 -0.19 -0.23 0.43 0.38 0.03 -0.16 -0.19 0.25 0.01 -0.05 0.52 0.31
172 || orf19.2583.2 || || || Pseudogene; formerly an ORF Predicted by Annotation Working Group || 1 -0.21 -0.03 0.56 0.60 0.02 -0.26 0.33 0.62 0.05 -0.38 -0.28 0.45 0.06 -0.41 0.09 0.39
173 || orf19.5423 || EST3 || || Telomerase subunit; required for telomere maintenance in vivo; separable roles in telomerase activity and processivity; not required for catalytic activity in vitro; related to mammalian Tpp1p || 1 0.05 -0.15 0.60 0.55 0.37 -0.08 0.65 0.63 0.23 -0.07 -0.16 0.33 -0.05 0.23 -0.05 0.72
174 || orf19.3735 || || || Protein of unknown function; induced by alpha pheromone in SpiderM medium || 1 1.14 -0.47 0.48 0.60 0.43 0.14 0.90 0.97 0.04 -0.58 -0.15 0.88 0.28 -0.07 0.26 0.44
175 || orf19.1551 || || || Predicted protein of unknown function; overlaps CPR3/orf19.1552 || 1 0.04 -0.55 0.59 0.19 0.53 0.31 0.10 0.35 0.07 -0.54 -0.55 0.67 -0.14 0.51 0.22 0.42
176 || orf19.478 || || || Protein required for fusion of cvt-vesicles and autophagosomes with the vacuole; plays a role in autophagy, protein targeting to vacuole and vesicle docking; flow model biofilm induced || 1 -0.03 -0.19 0.60 0.17 0.11 0.16 -0.04 0.13 0.25 -0.54 -0.20 0.34 0.09 -0.03 0.09 0.41
177 || orf19.7299.1 || || || Ortholog of Candida albicans WO-1 : CAWG_02179 || 1 -0.43 -0.38 1.48 -0.06 0.19 0.16 -0.05 0.63 -0.77 0.04 -0.11 -0.28 0.01 0.12 0.69
178 || orf19.3966 || CRH12 || || CRH family cell wall protein; transcript regulated by Nrg1 and Tup1; alkaline induced by Rim101; repressed during cell wall regeneration; flow model biofilm induced || 1 0.29 0.40 0.52 -0.01 0.35 -0.39 -0.17 0.45 -0.88 -0.04 0.01 0.46 0.15 -0.37 -0.14 0.73
179 || orf19.2943.5 || || || Ortholog of Candida albicans WO-1 : CAWG_05543 || 1 0.47 0.20 0.46 0.57 -0.06 -0.09 -0.25 -0.16 -0.56 -0.06 -0.11 0.31 -0.03 -0.31 -0.45 0.64
180 || orf19.584 || || || Has domain(s) with predicted heme binding, peroxidase activity and role in oxidation-reduction process, response to oxidative stress || 1 -0.16 -0.24 1.08 0.34 -0.11 0.07 -0.00 -1.38 0.15 0.03 -0.19 -0.41
181 || orf19.1724 || || || Protein of unknown function; induced by nitric oxide independent of Yhb1p || 1 0.05 0.10 1.05 0.13 -0.34 -0.26 -1.43 -0.21 -0.20 0.19 0.38 0.05 -0.16 1.21
182 || orf19.2203 || || || Ortholog of Candida albicans WO-1 : CAWG_05873 || 1 0.34 0.32 2.35 0.61 0.83 -0.05 -0.54 -0.00 -1.18 0.27 -0.35 1.20
183 || orf19.4803 || || || Ortholog of Candida albicans WO-1 : CAWG_00488 || 1 -0.09 0.80 2.08 1.07 0.65 0.21 0.23 -0.55 0.33 0.17 -0.26 -0.02
184 || orf19.450 || || || Protein of unknown function || 1 0.33 1.55 0.69 0.38 0.43 0.93 0.03 -0.31 -0.52 -0.28 0.40 0.54 -0.43 -0.84 0.78 1.17
185 || orf19.2370 || DSL1 || || Protein similar to S. cerevisiae Dsl1p, which is a member of the t-SNARE complex of the endoplasmic reticulum || 1 0.14 0.52 0.47 0.36 0.03 0.39 -0.05 -0.25 -0.01 -0.27 0.22 0.62 0.03 0.20 0.20 0.74
186 || orf19.599 || || || Dubious open reading frame || 1 -0.20 1.00 1.20 0.54 0.10 -0.30 -0.10 -0.12 0.16 0.16 0.48 0.15 -0.08 0.32 1.88
187 || orf19.2324 || UBA4 || || Putative ubiquitin activating protein; Hap43-repressed; induced by prostaglandins; clade-associated gene expression || 1 -0.14 0.70 0.26 0.16 -0.02 0.18 -0.01 -0.04 -0.11 -0.52 -0.02 0.04 -0.21 0.02 -0.25 0.89
188 || orf19.3336 || || || Ortholog of Candida albicans WO-1 : CAWG_01228 || 1 -0.21 0.61 0.21 -0.01 0.16 0.40 -0.23 0.61 -0.59 -0.21 -0.07 0.07 -0.32 0.29 1.29
189 || orf19.298 || || || Protein of unknown function; flow model biofilm induced || 1 0.58 0.25 0.66 -0.51 0.37 -0.12 -0.37 0.42 0.17 -0.31 -0.22 -0.43 0.05 0.60
190 || orf19.4366 || || || Ortholog of C. dubliniensis CD36 : Cd36_28870, Candida tropicalis MYA-3404 : CTRG_00731 and Candida albicans WO-1 : CAWG_01703 || 1 0.14 0.45 1.16 -0.02 0.23 0.11 -0.02 0.07 -0.05 -0.21 -0.25 -0.79 0.32 0.28
191 || orf19.3159.4 || || || Ortholog of Candida albicans WO-1 : CAWG_04594 || 1 0.54 0.10 0.31 -0.12 -0.28 -0.02 -0.11 -0.26 -0.07 -0.03 0.26 -0.58 -0.98 -0.14 0.34
192 || orf19.6949 || || || Ortholog of Candida albicans WO-1 : CAWG_02687 || 1 0.88 0.29 0.37 0.05 -0.32 0.40 -0.70 0.47 -0.16 -0.06 -0.23 -0.45 1.13 0.29
193 || orf19.2914 || || || Ortholog of C. dubliniensis CD36 : Cd36_45760, C. parapsilosis CDC317 : CPAR2_401920, Candida tenuis NRRL Y-1498 : CANTEDRAFT_126814 and Debaryomyces hansenii CBS767 : DEHA2D16742g || 1 0.52 0.39 0.19 0.18 -0.18 -0.10 0.21 0.00 0.25 0.12 -0.14 0.29 0.08 0.09 0.32 -0.11
194 || orf19.17 || SCP1 || || Putative cortical actin cytoskeleton protein; constitutive expression independent of MTL or white-opaque status || 1 0.81 0.61 0.87 0.42 -0.09 0.09 0.12 -0.13 -0.08 -0.14 0.13 0.17 -0.41 0.10 0.50 0.05
195 || orf19.17 || SCP1 || || Putative cortical actin cytoskeleton protein; constitutive expression independent of MTL or white-opaque status || 1 1.03 0.88 0.31 0.41 0.05 0.22 0.63 -0.00 -0.21 0.06 -0.08 0.29 -0.23 -0.19 0.68 0.68
196 || orf19.4474 || || || Ortholog(s) have cytoplasm, nucleus localization || 1 1.00 0.81 -0.07 0.37 0.01 0.05 0.21 0.03 -0.27 0.05 0.26 0.23 -0.54 -0.43 0.76 -0.07
197 || orf19.5172 || LIP9 || || Secreted lipase, member of a lipase gene family whose members are expressed differentially in response to carbon source and during infection; may have a role in nutrition and/or in creating an acidic microenvironment || 1 -0.12 0.15 -0.32 0.73 0.00 0.06 -0.43 -0.22 0.33 -0.21 -0.19 -0.25 0.57 -0.25 -0.42
198 || orf19.2084 || CDH1 || || Protein involved in regulation of mitosis; similar to S. cerevisiae Cdh1, which is an APC/C component; transcriptionally induced by Mnl1 under weak acid stress || 1 -0.19 -0.15 0.03 0.72 0.20 0.39 -0.20 -0.13 0.02 -0.14 -0.00 0.04 0.06 0.07 0.14 -0.41
199 || orf19.6164 || || || Ortholog of Candida albicans WO-1 : CAWG_02424 || 1 0.71 0.38 -0.23 2.18 0.46 1.73 -0.11 -0.44 0.22 -0.03 0.53 -0.33 -0.11 -0.26
200 || orf19.6164 || || || Ortholog of Candida albicans WO-1 : CAWG_02424 || 1 0.43 0.50 -0.79 2.56 0.91 -0.14 -0.42 0.60 0.64 -0.27 0.37 0.17 -0.05
201 || orf19.2203 || || || Ortholog of Candida albicans WO-1 : CAWG_05873 || 1 0.32 -0.66 -0.25 2.37 -0.62 -0.25 -0.28 0.96 1.79 -0.17 0.42 -0.15 0.05 -0.51 0.34
202 || orf19.1874 || || || Ortholog(s) have protein serine/threonine kinase activity, role in meiosis, meiotic recombination checkpoint, protein phosphorylation, regulation of linear element assembly and cytosol, linear element localization || 1 -0.64 -0.62 1.61 -0.00 -0.12 -0.09 -0.70 0.66 -0.28 0.38 -0.39 0.27 -0.06 -0.15
203 || orf19.4803 || || || Ortholog of Candida albicans WO-1 : CAWG_00488 || 1 -0.19 -0.09 0.29 1.62 0.07 0.75 -0.38 -0.21 -0.59 0.72 -0.47 0.27 0.30 -0.22 -0.65 0.86
204 || orf19.7516 || || || Putative glycoside hydrolase; Hap43-induced gene || 1 -0.44 -0.35 0.25 1.10 0.54 0.48 -0.43 -0.17 -0.51 -0.04 0.08 0.46 -0.47 -0.56 0.11 0.32
205 || orf19.2514 || || || Predicted methyltransferase; rat catheter biofilm induced || 1 -0.02 0.04 0.18 0.45 0.23 0.67 -0.34 -0.17 -0.25 0.21 0.06 0.42 -0.29 -0.08 0.45 0.21
206 || orf19.2445 || || || Putative dicarboxylic amino acid permease; fungal-specific (no human or murine homolog); induced by alpha pheromone in SpiderM medium || 1 -0.17 -0.22 -0.01 0.64 0.29 0.71 0.32 -0.33 -0.43 -0.43 0.12 0.44 -0.31 -0.46 0.86 -0.16
207 || orf19.4403 || VPS11 || || Protein involved in protein trafficking; putative role in vesicle-target membrane fusion; mutant lacks vacuole; role in hyphal growth, possibly via vacuole expansion into hypha; role in killing of and survival within macrophage || 1 0.29 0.50 0.18 0.57 -0.01 0.05 -0.00 0.04 -0.19 -0.12 -0.35 0.14 0.06 0.02 0.25 0.26
208 || orf19.4601 || || || Putative RNA polymerase III transcription initiation factor complex (TFIIIC) subunit; possibly an essential gene, disruptants not obtained by UAU1 method || 1 0.61 0.27 0.34 0.33 0.17 0.06 0.23 0.12 -0.15 0.16 0.04 -0.02 0.29 0.31 0.14 0.38
209 || orf19.2832 || INN1 || || Protein with similarity to S. cerevisiae Inn1p, which is an essential protein of the contractile actomyosin ring required for ingression of the plasma membrane into the bud neck during cytokinesis; contains a C2 membrane targeting domain || 1 0.45 0.37 0.27 0.69 -0.14 0.13 0.68 -0.06 0.01 0.07 -0.30 -0.01 0.08 0.28 -0.05 0.62
210 || orf19.7356 || || || Ortholog of C. parapsilosis CDC317 : CPAR2_807080, C. dubliniensis CD36 : Cd36_85690, Candida orthopsilosis Co 90-125 : CORT_0C02090 and Candida albicans WO-1 : CAWG_02885 || 1 0.18 1.43 0.99 1.47 0.32 0.52 1.04 0.06 0.02 0.14 -1.25 -0.68 -0.10 2.23 0.52 0.64
211 || orf19.998 || || || Putative adapter protein; links synaptojanins Inp52 and Inp53 to the cortical actin cytoskeleton in S. cerevisiae; mutants are viable || 1 0.05 0.04 0.41 0.90 0.10 0.72 -0.20 -0.24 0.28 0.26 -0.57 0.48 0.03 1.05 -0.15 0.43
212 || orf19.109 || || || Probable mitochondrial tyrosyl-tRNA synthetase, based on conservation in other fungi || 1 -0.06 0.00 0.22 0.22 -0.15 0.50 0.23 -0.15 0.36 0.11 -0.28 0.36 -0.14 0.41 -0.03 0.67
213 || orf19.5588 || PGA60 || || Putative GPI-anchored adhesin-like protein; hyphal-induced expression || 1 0.20 0.05 0.47 0.34 -0.45 0.50 0.01 -0.31 0.22 -0.04 -0.58 0.57 -0.13 0.55 -0.26 1.00
214 || orf19.465 || IFF9 || || Predicted GPI-linked cell-wall protein; similar to Hyr1; induced in low iron; possibly an essential gene, disruptants not obtained by UAU1 method || 1 0.38 0.83 0.50 0.52 -0.20 0.90 0.11 0.14 0.55 -0.25 -0.21 -0.00 -0.09 0.51 -0.15 1.02
215 || orf19.2281 || || || Ortholog(s) have mitochondrion localization || 1 0.26 0.25 0.09 0.71 -0.29 0.24 -0.25 0.28 0.71 -0.30 -0.18 -0.12 0.35 0.50 0.02 0.54
216 || orf19.2059 || || || Protein with homology to magnesium-dependent endonucleases and phosphatases; regulated by Sef1, Sfu1, and Hap43; Spider biofilm induced || 1 0.04 -0.26 0.52 0.69 0.68 0.96 0.05 0.81 0.06 -0.59 -0.06 -0.73 0.71 0.22 0.20 0.91
217 || orf19.6307 || || || Ortholog of C. dubliniensis CD36 : Cd36_30250, Candida tenuis NRRL Y-1498 : CANTEDRAFT_98619, Debaryomyces hansenii CBS767 : DEHA2G22594g and Pichia stipitis Pignal : PICST_50168 || 1 0.46 -0.09 0.28 0.42 0.52 0.65 -0.14 0.30 -0.08 -0.58 -0.24 -0.31 0.56 -0.17 0.37 -0.02
218 || orf19.3851 || || || Protein of unknown function; induced by alpha pheromone in SpiderM medium || 1 0.17 0.02 0.19 0.44 0.73 0.18 0.04 0.04 0.22 -0.21 -0.21 -0.53 0.33 0.11 0.50 0.07
219 || orf19.2539 || || || Protein of unknown function; transcript detected on high-resolution tiling arrays || 1 0.50 0.25 0.81 0.23 0.80 0.33 -0.26 0.54 1.03 0.18 0.02 -1.48 0.71 0.13 1.52 0.71
220 || orf19.5215 || TES15 || || Putative acyl-CoA thioesterase; Hap43-repressed; Spider biofilm induced || 1 0.25 0.21 0.61 0.17 0.53 -0.09 -0.27 0.30 0.65 0.07 -0.09 -1.32 0.66 0.41 0.25 0.20
221 || orf19.4767 || ZCF28 || || Zn(II)2Cys6 transcription factor; required for yeast cell adherence to silicone substrate; Spider biofilm induced || 1 0.09 0.06 1.37 0.17 0.10 0.19 -0.05 -0.02 0.45 -0.17 -0.42 -0.63 0.23 -0.64 0.11 -0.29
222 || orf19.6280 || || || Dubious open reading frame || 1 -0.25 0.24 4.06 0.19 0.37 -0.17 -0.34 -0.21 0.64 0.44 -0.47 0.44
223 || orf19.2025 || || || Dubious open reading frame || 1 -0.20 0.14 1.04 -0.12 0.25 0.84 0.08 -0.12 0.69 -0.09 -0.14 -0.15 0.17 0.09 -0.26 0.36
224 || orf19.5492 || || || Ortholog(s) have mRNA binding, pre-mRNA 5'-splice site binding activity, role in mRNA 5'-splice site recognition and U1 snRNP, U2-type prespliceosome, commitment complex localization || 1 0.10 0.08 0.21 -0.07 0.09 0.22 -0.21 -0.16 0.19 -0.08 -0.44 0.04 0.19 0.04 -0.15 0.38
225 || orf19.4372 || || || Predicted transmembrane transporter; rat catheter and Spider biofilm induced || 1 0.37 0.65 0.53 0.30 0.51 0.44 -0.17 -0.25 0.50 -0.57 -0.41 -0.19 0.30 0.40 -0.20 0.38
226 || orf19.2010 || || || Ortholog of C. dubliniensis CD36 : Cd36_16030, C. parapsilosis CDC317 : CPAR2_213800, Debaryomyces hansenii CBS767 : DEHA2A01320g and Pichia stipitis Pignal : PICST_29434 || 1 0.22 0.90 0.88 0.24 0.62 0.62 -0.52 -0.12 0.22 -0.55 -0.65 0.16 0.13 -0.59
227 || orf19.1738 || UGP1 || || UTP-glucose-1-phosphaturidyl transferase; localizes to yeast, not hyphal cell surface; Hog1-repressed; stationary phase enriched; induced in oralpharyngeal candidasis; rat catheter biofilm repressed; Bcr1-repressed in RPMI a/a biofilms || 1 0.32 0.31 0.35 0.22 0.26 0.04 -0.07 -0.10 -0.16 -0.31 -0.28 0.06 -0.03 0.38 -0.08 0.22
228 || orf19.3360 || || || Protein of unknown function; flow model biofilm induced; Spider biofilm induced || 1 0.41 0.49 0.71 0.50 0.71 0.47 -0.18 -0.89 0.02 -0.48 -0.86 -0.68 0.51 0.41 0.15 0.31
229 || orf19.2432 || HAC1 || || bZIP transcription factor; role in unfolded protein response and control of morphology; transcript undergoes atypical splicing at C terminus under ER stress; induced during mating and by caspofungin; mRNA binds She3; Spider biofilm induced || 1 0.56 0.42 1.06 0.71 0.12 0.49 -0.01 -0.89 -0.17 -0.19 -1.12 -0.64 1.05 0.00 0.68 -0.13
230 || orf19.4328 || CCC2 || || Copper-transporting P-type ATPase of Golgi; required for wild-type iron assimilation (indirect effect via Fet3p); induced by iron starvation, ciclopirox olamine; caspofungin repressed; not required for virulence in mouse systemic infection || 1 1.00 0.40 0.88 0.71 0.41 0.71 -0.31 -0.13 -0.60 -0.42 -0.84 -0.92 1.15 0.64 0.09 -0.45
231 || orf19.4315 || || || Ortholog(s) have Rab GTPase activator activity, role in vesicle-mediated transport and intracellular localization || 1 0.40 0.27 0.39 0.38 0.53 0.56 -0.21 -0.16 -0.14 -0.24 -0.03 -0.27 0.58 0.18 -0.07 0.07
232 || orf19.5616 || || || Ortholog of C. dubliniensis CD36 : Cd36_63740, C. parapsilosis CDC317 : CPAR2_503850, Pichia stipitis Pignal : PICST_32045 and Candida guilliermondii ATCC 6260 : PGUG_00070 || 1 0.58 0.87 0.20 0.88 0.33 0.28 0.18 -0.17 -0.10 0.56 -0.26 -0.59 1.20 0.28 -0.65 -0.29
233 || orf19.4643 || || || Ortholog of C. dubliniensis CD36 : Cd36_41430, Candida tropicalis MYA-3404 : CTRG_00187 and Candida albicans WO-1 : CAWG_03642 || 1 0.22 0.38 0.57 0.47 0.34 -0.19 -0.25 -0.03 0.04 0.72 -0.13 -0.35 0.27 0.58 -0.19 -0.21
234 || orf19.2740 || || || Ortholog(s) have 5'-flap endonuclease activity || 1 0.13 0.12 0.34 0.31 0.50 0.19 -0.13 -0.02 0.16 0.54 -0.32 -0.09 0.06 0.31 -0.30 -0.23
235 || orf19.6903 || || || Predicted RNA polymerase III subunit C37; Spider biofilm induced || 1 0.56 0.30 0.87 0.70 0.80 0.78 0.09 -0.00 0.19 0.88 0.08 -0.12 0.91 0.24 -0.03 -0.81
236 || orf19.5020 || || || Protein of unknown function; Hap43-induced; Spider biofilm induced || 1 0.15 0.29 0.85 0.37 0.26 0.66 -0.18 -0.17 -0.28 1.27 -0.31 -0.16 0.79 0.05 0.20 -0.67
237 || orf19.177 || || || Has domain(s) with predicted phosphatidylinositol binding activity and role in cell communication || 1 0.13 0.21 0.23 0.68 0.50 0.33 -0.14 -0.24 0.18 0.74 0.02 0.42 0.47 0.14 0.41 0.05
238 || orf19.4539 || || || Protein with a Rho GDP-dissociation inhibitor domain; Hap43-repressed gene; Spider biofilm induced || 1 -0.22 -0.13 0.26 0.60 0.08 -0.22 -0.13 0.20 0.25 0.22 -0.01 0.07 0.26 0.15 -0.02 -0.24
239 || orf19.5083 || DRG1 || || Member of the DRG family of GTP-binding proteins; involved in regulation of invasive filamentous growth || 1 -0.24 0.06 1.09 0.63 0.06 -0.46 0.35 0.17 0.00 0.30 0.38 0.12 0.11 -0.08 -0.01 -0.17
240 || orf19.2468 || || || Ortholog(s) have trans-aconitate 3-methyltransferase activity and cytosol, nucleus localization || 1 -0.34 0.19 1.41 0.66 0.44 -0.58 0.05 -0.17 -0.17 0.96 0.49 -0.49 0.26 -0.24 0.49 -1.19
241 || orf19.7216 || YPT52 || || Rab-family GTPase involved in vacuolar trafficking, colocolizes with Vps1p and Ypt53p in late endosome || 1 0.27 0.36 0.40 0.48 0.18 0.01 0.04 0.36 0.22 0.35 0.39 0.14 -0.01 0.13 0.30 -0.54
242 || orf19.6972 || SMI1B || || Putative cell wall assembly regulatory protein; Rim101-repressed; possibly an essential gene, disruptants not obtained by UAU1 method || 1 0.20 0.34 0.68 0.41 0.33 -0.50 0.12 0.49 0.28 0.32 0.43 0.49 0.74 0.03 0.45 -0.52
243 || orf19.2697 || || || Ortholog(s) have role in protein monoubiquitination, regulation of dipeptide transmembrane transport by regulation of transcription from RNA polymerase II promoter and cytoplasm, nucleus localization || 1 -0.09 0.13 0.39 0.39 0.27 -0.17 -0.33 0.11 0.32 0.49 -0.02 0.23 0.23 -0.09 -0.17 -0.12
244 || orf19.2956 || MGM101 || || Putative mitochondrial genome maintenance protein; fungal-specific (no human or murine homolog); mutation confers hypersensitivity to tubercidin (7-deazaadenosine) || 1 -0.09 0.16 0.51 0.50 -0.02 -0.02 0.01 0.46 0.47 0.24 0.01 0.03 -0.01 -0.46 -0.01 -0.09
245 || orf19.3227 || FTH2 || || Putative iron transporter; similar to S. cerevisiae Fth1p || 1 0.00 0.14 0.69 0.65 0.05 -0.28 0.13 0.27 0.16 0.43 -0.16 0.16 0.26 -0.25 0.27 0.05
246 || orf19.5808 || || || Ortholog(s) have protein-lysine N-methyltransferase activity, role in negative regulation of G2/M transition of mitotic cell cycle, peptidyl-lysine methylation and cytosol, nucleus localization || 1 0.47 0.28 0.65 0.60 0.70 0.13 -0.02 0.06 0.18 0.33 0.19 0.22 0.31 -0.40 0.11 -0.31
247 || orf19.7625 || PGA1 || || Putative GPI-anchored protein; induced during cell wall regeneration; required for normal adhesion to host cells and for adherence during Sabouraud biofilm formation; Spider biofilm induced || 1 0.15 0.17 0.45 0.54 0.20 -0.18 -0.29 0.03 0.06 0.35 0.06 0.30 0.32 -0.44 0.28 -0.47
248 || orf19.6284 || || || Ortholog(s) have GTP binding, signal recognition particle binding activity, role in protein targeting to ER and integral to endoplasmic reticulum membrane localization || 1 0.02 0.15 0.35 0.45 0.11 -0.14 -0.25 0.08 0.20 0.12 0.11 0.21 0.23 -0.25 0.10 -0.10
249 || orf19.10712 || MTLALPHA1 || || Master regulator (activator) of alpha mating type; gene of the MTLalpha (Mating Type Like) locus; ortholog of S. cerevisiae Alpha1p; a/alpha mating type may increase virulence, offers competitive advantage || 1 0.01 0.10 0.66 0.86 0.43 0.22 -0.06 0.30 0.17 0.20 -0.04 0.70 0.18 -0.55 0.28 -0.26
250 || orf19.3404 || || || Protein of unknown function; transcription repressed by fluphenazine treatment || 1 -0.04 0.17 0.63 0.43 -0.00 0.32 -0.18 0.09 0.06 -0.14 0.09 0.35 0.35 -0.40 -0.03 -0.45
251 || orf19.3694 || || || Ortholog of C. dubliniensis CD36 : Cd36_02210, C. parapsilosis CDC317 : CPAR2_106350, Candida tenuis NRRL Y-1498 : CANTEDRAFT_116785 and Debaryomyces hansenii CBS767 : DEHA2C01980g || 1 0.05 0.39 0.80 0.92 0.35 -0.19 0.04 0.11 -0.27 -0.08 0.30 0.24 0.56 0.17 0.22 -0.11
252 || orf19.1112 || BUD7 || || Ortholog(s) have role in Golgi to plasma membrane transport, fungal-type cell wall chitin biosynthetic process and cell division site, clathrin-coated vesicle, cytosol, exomer complex, nucleus, ribosome localization || 1 0.18 0.43 0.48 0.24 0.24 -0.17 -0.11 -0.11 -0.11 -0.03 0.00 0.26 0.21 0.03 0.01 -0.13
253 || orf19.5411 || || || Ortholog(s) have NEDD8 ligase activity, role in protein neddylation, regulation of mitotic cell cycle and cytosol, nucleus localization || 1 0.14 0.47 0.74 0.46 0.58 -0.15 -0.27 -0.14 -0.19 -0.34 -0.15 0.19 0.55 -0.05 0.01 0.22
254 || orf19.2342 || SFT2 || || Putative membrane protein; transcript regulated by Mig1; Spider biofilm induced || 1 0.38 0.36 0.80 0.62 0.47 -0.12 -0.40 0.01 0.19 -0.09 -0.30 -0.20 0.07 0.07 0.30 0.14
255 || orf19.3982 || || || Maltase; induced during growth on sucrose; induced by alpha pheromone in SpiderM medium; early-stage flow model biofilm indced || 1 0.86 0.91 0.51 0.67 0.16 0.25 -0.22 0.23 0.36 0.74 -0.71 -0.61 -0.57 0.15 -0.30 0.32
256 || orf19.1374 || || || Ortholog of C. dubliniensis CD36 : Cd36_23840, Candida tenuis NRRL Y-1498 : CANTEDRAFT_104074, Debaryomyces hansenii CBS767 : DEHA2B13310g and Pichia stipitis Pignal : PICST_58235 || 1 0.48 0.61 0.48 0.58 0.58 0.79 0.01 0.19 0.10 0.48 -0.06 -0.25 -0.16 -0.00 -0.10 0.06
257 || orf19.1374 || || || Ortholog of C. dubliniensis CD36 : Cd36_23840, Candida tenuis NRRL Y-1498 : CANTEDRAFT_104074, Debaryomyces hansenii CBS767 : DEHA2B13310g and Pichia stipitis Pignal : PICST_58235 || 1 0.69 0.88 0.30 0.53 0.54 0.58 -0.20 -0.08 0.12 0.96 -0.15 -0.25 -0.20 -0.45 -0.38 -0.27
258 || orf19.1030 || || || Putative peptidyl-prolyl cis-trans isomerase || 1 1.02 0.70 0.51 0.16 0.58 0.53 -0.20 0.31 -0.04 0.52 0.18 -0.70 0.37 -0.06 -0.66 0.21
259 || orf19.500 || || || Ortholog(s) have tRNA (adenine-N1-)-methyltransferase activity, role in tRNA methylation and nucleus, tRNA (m1A) methyltransferase complex localization || 1 1.09 1.11 1.03 0.78 1.09 1.33 0.26 1.27 -0.26 0.52 0.31 -1.11 0.44 -0.11 0.14 -0.60
260 || orf19.5264 || || || Dubious open reading frame || 1 0.19 0.28 0.47 1.43 1.16 0.28 0.20 0.53 -0.46 -0.32 0.35 0.23
261 || orf19.182 || || || Ortholog(s) have rRNA (guanine-N1-)-methyltransferase activity, role in rRNA modification and endoplasmic reticulum, mitochondrion localization || 1 0.12 0.12 0.44 0.39 0.51 0.52 -0.08 0.22 0.15 0.47 -0.13 0.03 0.02 -0.39 0.03 -0.77
262 || orf19.1966 || BUD23 || || Putative methyltransferase; Hap43-induced; repressed by prostaglandins || 1 0.10 -0.02 0.48 0.32 0.56 0.65 -0.01 0.45 -0.28 0.31 -0.32 -0.80 0.28 -0.26 -0.09 -0.62
263 || orf19.5207 || || || Predicted diphthamide biosynthesis protein; Spider biofilm induced || 1 0.28 0.24 0.43 0.64 0.36 1.00 -0.18 0.04 -0.13 0.68 -0.48 -0.57 0.02 -0.34 -0.01 -0.62
264 || orf19.2090 || || || Ortholog of S. cerevisiae Ecm16, an essential DEAH-box ATP-dependent RNA helicase specific to the U3 snoRNP required for 18S rRNA synthesis; Hap43-induced; Spider biofilm induced || 1 0.03 0.07 0.43 0.61 0.59 1.05 -0.02 0.11 -0.32 0.55 -0.28 -1.17 -0.29 -0.64 -0.04 -0.73
265 || orf19.7398 || || || Protein of unknown function' Hap43-induced gene; repressed by prostaglandins || 1 0.14 0.16 0.38 0.62 0.12 1.13 -0.08 -0.01 -0.15 0.16 -0.59 -1.63 0.03 -0.63 -0.22 -1.37
266 || orf19.7280 || || || Ortholog of Candida albicans WO-1 : CAWG_02163 || 1 0.17 0.26 0.44 0.16 0.23 1.03 0.26 0.21 0.34 0.41 -0.51 0.37 0.39 -1.90
267 || orf19.3630 || RRP8 || || Ribosomal protein; Hap43-induced; F-12/CO2 early biofilm and rat catheter biofilm induced || 1 0.41 0.58 0.67 0.18 0.95 1.26 0.02 -0.19 0.11 0.49 -0.47 -0.92 0.67 -0.38 0.24 -1.83
268 || orf19.475 || || || Putative rRNA processing protein; rat catheter biofilm induced || 1 0.93 1.08 0.88 0.89 1.13 1.37 0.19 -0.16 -0.51 0.53 -0.51 -1.11 0.83 -0.49 -0.27 -2.69
269 || orf19.6236 || NOP6 || || Putative ortholog of S. cerevisiae Nop6; role in ribosomal small subunit biogenesis; Spider biofilm induced || 1 -0.03 0.39 1.03 0.40 0.58 1.82 -0.23 -0.59 0.09 0.74 -0.62 -0.88 0.35 0.08 -0.58 -1.26
270 || orf19.4399 || NCS2 || || Putative cytosolic thiouridylase subunit; Spider biofilm induced || 1 0.06 0.28 0.44 0.20 0.44 1.03 -0.19 -0.06 -0.01 0.32 -0.13 -0.34 0.57 0.32 0.07 -0.53
271 || orf19.4701 || || || Ortholog(s) have ATPase activity, tRNA binding activity, role in protein urmylation, regulation of transcription from RNA polymerase II promoter, tRNA wobble uridine modification and Elongator holoenzyme complex localization || 1 0.22 0.21 0.03 0.05 0.79 1.20 0.08 -0.04 -0.08 0.74 -0.91 -0.74 0.78 -0.00 0.01 -1.06
272 || orf19.5845 || RNR3 || || Putative ribonucleotide reductase large subunit; transcript induced in low iron; rat catheter and Spider biofilm induced || 1 0.77 1.09 0.12 0.98 0.81 1.30 0.28 -0.35 -0.05 0.85 -1.36 -1.05 0.67 0.10 0.73 -1.54
273 || orf19.7502 || || || Protein of unknown function; Hap43-induced gene; upregulated in a cyr1 null mutant; Spider biofilm induced || 1 1.00 0.86 0.53 0.19 1.27 1.36 -0.35 -0.33 -0.90 0.83 -1.91 -1.08 1.16 0.09 1.08 -1.63
274 || orf19.7502 || || || Protein of unknown function; Hap43-induced gene; upregulated in a cyr1 null mutant; Spider biofilm induced || 1 0.74 0.75 0.89 0.71 0.96 1.39 -0.69 -0.83 -1.10 0.36 -2.38 -0.78 0.90 0.07 0.78 -1.90
275 || orf19.6941 || || || Putative diacylglycerol acyltransferase; catalyzes the terminal step of triacylglycerol formation; flow model biofilm induced; Spider biofilm induced || 1 0.76 0.68 0.95 1.46 0.99 0.83 0.39 -0.03 0.56 0.02 -1.94 -1.08 0.66 0.59 0.97 -0.84
276 || orf19.6941 || || || Putative diacylglycerol acyltransferase; catalyzes the terminal step of triacylglycerol formation; flow model biofilm induced; Spider biofilm induced || 1 0.47 0.46 0.96 0.92 0.66 0.92 0.15 -0.42 0.35 -0.34 -2.61 -1.54 0.64 0.61 0.70 -1.45
277 || orf19.409 || || || Ortholog of S. cerevisiae Aim38/Rcf2, cytochrome c oxidase subunit; plasma membrane localized; Hap43-repressed; induced in oralpharyngeal candidasis; flow model biofilm induced; Spider biofilm repressed || 1 0.89 0.81 0.72 0.72 0.93 1.51 0.01 0.07 0.45 -0.66 -1.48 -2.25 -0.14 0.31 0.52 -1.78
278 || orf19.409 || || || Ortholog of S. cerevisiae Aim38/Rcf2, cytochrome c oxidase subunit; plasma membrane localized; Hap43-repressed; induced in oralpharyngeal candidasis; flow model biofilm induced; Spider biofilm repressed || 1 1.17 1.11 1.17 1.04 1.12 1.84 0.58 0.58 0.28 -0.95 -1.05 -2.12 0.17 -0.07 0.73 -1.45
279 || orf19.2620 || || || Ortholog of C. dubliniensis CD36 : Cd36_33120 and Candida albicans WO-1 : CAWG_02046 || 1 -0.05 -0.03 0.67 0.34 1.74 1.58 -0.29 -0.35 0.20 -0.65 -2.05 -2.35 0.16 0.03 0.58 -1.82
280 || orf19.7068 || MAC1 || || Copper fist transcription factor; regulator of CTR1 copper transporter; induces CTR1 in low-copper conditions; ectopic expression causes copper-sensitive stimulation of filamentation in S. cerevisiae; Spider biofilm induced || 1 -0.05 0.13 0.10 -0.19 0.43 1.00 -0.21 -0.34 0.07 -0.16 -1.16 -0.91 -0.23 0.39 -0.12 -0.66
281 || orf19.3704 || || || Ortholog(s) have role in maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA), maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) || 1 0.26 0.20 0.59 -0.04 0.97 1.27 -0.04 -0.37 -0.11 0.34 -0.31 -0.13 0.09 0.48 -0.54 -0.46
282 || orf19.5360 || RPC11 || || Putative RNA polymerase III subunit C11; repressed in core caspofungin response; Spider biofilm induced || 1 0.13 0.13 0.42 0.10 0.48 0.63 -0.08 -0.14 -0.04 0.07 -0.09 -0.14 0.17 0.36 0.00 0.04
283 || orf19.4369 || || || Ortholog of S. cerevisiae Spp41; protein involved in negative regulation of expression of spliceosome components PRP4 and PRP3 in S. cerevisiae; mutants are viable || 1 0.10 0.27 0.54 0.27 0.85 0.82 0.14 0.13 0.28 0.18 -0.28 0.07 0.32 0.21 -0.14 -0.04
284 || orf19.6049 || || || Ortholog(s) have protein kinase activator activity, role in protein phosphorylation, regulation of cytokinesis and chromosome passenger complex, kinetochore microtubule, spindle midzone localization || 1 0.12 0.25 0.60 0.05 0.72 0.68 -0.22 -0.15 0.42 0.10 -0.57 0.04 0.05 0.28 -0.01 -0.28
285 || orf19.1771 || CWC22 || || Predicted spliceosome-associated protein; role in pre-mRNA splicing; Spider biofilm induced || 1 0.44 0.50 0.49 0.18 1.19 1.90 -0.37 -0.35 -0.16 0.49 -0.63 0.15 0.18 -0.89 0.68 -0.99
286 || orf19.4133 || || || Protein wth a predicted role in transcription from RNA polymerase II promoters; Spider biofilm induced || 1 0.79 0.54 0.63 0.45 1.66 1.79 -0.11 -0.47 -0.48 0.09 -0.46 -0.03 0.31 -0.42 0.73 -0.67
287 || orf19.480 || || || Protein of unknown function; rat catheter and Spider biofilm induced || 1 0.59 0.26 0.47 0.51 0.79 0.92 -0.24 -0.35 -0.51 0.12 -0.32 0.07 0.15 -0.26 0.11 -0.71
288 || orf19.3759 || || || Putative elongator complex subunit; for modification of wobble nucleosides in tRNA; Spider biofilm induced || 1 0.34 0.16 0.49 0.71 1.30 1.71 0.20 -0.99 -1.68 0.04 -0.33 -0.61 0.17 -0.34 0.19 -1.04
289 || orf19.1029 || RPP1 || || Putative ortholog of S. cerevisiae Rpp1; subunit of both RNase MRP and nuclear RNase P; rat catheter and Spider biofilm induced || 1 0.80 0.81 0.25 0.24 1.31 1.62 0.03 -0.28 -1.09 -0.33 -0.25 -0.64 0.18 -0.33 0.48 -0.89
290 || orf19.3665 || SET6 || || Ortholog of S. cerevisiae Set6, a SET domain protein of unknown function; Hap43-induced; rat catheter and Spider biofilm induced || 1 0.45 0.35 1.00 1.01 0.60 1.47 -0.20 -0.05 -0.74 -0.43 -0.25 -0.52 0.17 -0.42 -0.01 -0.38
291 || orf19.2193 || PRS5 || || Putative 5-phospho-ribosyl-1(alpha)-pyrophosphate synthetase; Hap43-induced; repressed during core stress response || 1 0.24 0.29 0.65 0.62 0.75 1.36 -0.03 -0.18 -0.52 0.12 -0.02 -0.59 -0.01 -0.22 -0.08 -0.75
292 || orf19.4363 || SGD1 || || Predicted small ribosomal subunit biogenesis protein; repressed in core stress response; transcript increases in populations of cells exposed to fluconazole over multiple generations; Spider biofilm induced || 1 0.62 0.68 0.81 0.87 1.21 1.27 0.03 -0.03 -0.22 0.30 0.03 -0.58 -0.15 -0.22 -0.25 -0.57
293 || orf19.3130 || || || Ortholog of S. cerevisiae Gpn3 a GTPase with a role in biogenesis of RNA pol II and polIII; possibly an essential gene, disruptants not obtained by UAU1 method || 1 0.67 0.52 0.77 0.72 0.97 1.42 -0.19 -0.12 -0.39 0.11 -0.61 -0.37 0.01 -0.69 -0.04 -0.50
294 || orf19.2527 || || || Putative protein of unknown function; Hap43-induced; required for normal biofilm growth; F-12/CO2 early biofilm induced || 1 0.56 0.74 0.57 0.55 1.03 1.80 0.03 0.05 -0.39 0.57 -0.19 -0.83 -0.08 0.19 0.09 0.03
295 || orf19.3393 || || || Putative DEAD-box helicase; Hap43-induced; Spider biofilm induced || 1 0.70 0.54 0.59 0.56 0.59 1.77 -0.16 -0.45 -1.00 0.77 -0.41 -0.55 -0.35 0.36 -0.08 -0.28
296 || orf19.5407 || SOF1 || || Putative protein with a predicted role in 40S ribosomal subunit biogenesis; rat catheter biofilm induced || 1 0.58 0.14 0.74 0.28 1.09 1.72 -0.18 -0.69 -0.73 0.50 -0.28 -0.98 -0.15 -0.08 0.37 -0.48
297 || orf19.5824 || || || Protein of unknown function; rat catheter and Spider biofilm induced || 1 0.73 0.98 0.86 0.46 0.85 1.21 -0.19 -0.42 -0.56 0.41 -0.77 -0.79 -0.38 -0.41 0.16 -0.64
298 || orf19.500 || || || Ortholog(s) have tRNA (adenine-N1-)-methyltransferase activity, role in tRNA methylation and nucleus, tRNA (m1A) methyltransferase complex localization || 1 0.68 0.87 0.70 0.05 0.84 0.95 -0.18 -0.36 -0.85 0.35 -0.03 -0.97 -0.40 -0.01 -0.02 -0.39
299 || orf19.5824 || || || Protein of unknown function; rat catheter and Spider biofilm induced || 1 0.38 0.63 1.02 0.43 0.84 1.29 -0.79 -1.17 -0.47 0.56 -0.96 -0.52 -0.44 -0.20 -0.21 -0.66
300 || orf19.6831 || PRP5 || || Putative pre-mRNA processing RNA-helicase; induced upon adherence to polystyrene; rat catheter and Spider biofilm induced || 1 0.34 0.70 0.97 0.55 1.24 1.57 -0.27 -0.87 -0.25 0.25 -0.81 -0.58 0.23 0.21 -0.32 -0.68
301 || orf19.4569 || || || Ortholog of C. dubliniensis CD36 : Cd36_42100, Debaryomyces hansenii CBS767 : DEHA2C14850g, Pichia stipitis Pignal : PICST_52615 and Spathaspora passalidarum NRRL Y-27907 : SPAPADRAFT_58608 || 1 0.56 0.68 0.98 0.94 0.84 0.72 -0.02 -0.19 0.04 -0.20 -0.83 -0.22 -0.29 0.19 -0.06 -0.02
302 || orf19.7356 || || || Ortholog of C. parapsilosis CDC317 : CPAR2_807080, C. dubliniensis CD36 : Cd36_85690, Candida orthopsilosis Co 90-125 : CORT_0C02090 and Candida albicans WO-1 : CAWG_02885 || 1 1.35 1.52 1.02 1.73 0.62 1.58 1.03 0.67 0.34 -0.42 -1.14 -0.95 -0.21 0.45 0.07 -0.96
303 || orf19.7356 || || || Ortholog of C. parapsilosis CDC317 : CPAR2_807080, C. dubliniensis CD36 : Cd36_85690, Candida orthopsilosis Co 90-125 : CORT_0C02090 and Candida albicans WO-1 : CAWG_02885 || 1 1.29 1.35 1.17 1.08 1.31 2.46 1.23 0.09 0.09 -0.49 -0.87 -0.16 0.13 0.76 0.34 -0.81
304 || orf19.2461 || PRN4 || || Protein with similarity to pirins; induced by benomyl treatment; flow model biofilm repressed || 1 1.02 1.22 1.08 1.13 1.50 1.92 0.09 0.38 0.22 0.12 -0.87 -0.81 -0.22 -0.06 0.64 -1.42
305 || orf19.2461 || PRN4 || || Protein with similarity to pirins; induced by benomyl treatment; flow model biofilm repressed || 1 1.14 1.35 1.12 1.26 1.68 1.90 0.40 0.60 0.58 0.31 -0.78 -0.75 -0.14 0.05 0.81 -1.74
306 || orf19.2215 || GLE1 || || Putative nucleoporin; moderately induced at 42 degrees C || 1 0.25 0.29 0.43 0.11 0.60 0.55 -0.11 -0.23 0.12 -0.21 -0.27 -0.16 0.11 -0.06 0.03 -0.42
307 || orf19.1007 || KCS1 || || Putative bZIP transcription factor; Spider biofilm induced || 1 1.47 1.49 1.12 0.27 1.70 2.61 -0.37 -0.58 -0.46 -0.73 -0.78 -0.79 0.17 -0.31 -0.70 -0.71
308 || orf19.6235 || || || Protein of unknown function; Spider biofilm induced || 1 0.75 0.73 0.94 0.52 1.27 1.39 -0.14 -0.37 -0.17 -0.51 -0.37 -0.56 0.02 -0.20 -0.14 -0.51
309 || orf19.2770 || || || Ortholog of C. dubliniensis CD36 : Cd36_42220, C. parapsilosis CDC317 : CPAR2_500340, Debaryomyces hansenii CBS767 : DEHA2G17754g and Pichia stipitis Pignal : PICST_31424 || 1 1.91 1.96 1.41 1.04 2.27 2.08 0.03 0.16 0.24 -0.32 -0.93 -0.51 -0.00 -0.25 -0.20 -0.21
310 || orf19.2770 || || || Ortholog of C. dubliniensis CD36 : Cd36_42220, C. parapsilosis CDC317 : CPAR2_500340, Debaryomyces hansenii CBS767 : DEHA2G17754g and Pichia stipitis Pignal : PICST_31424 || 1 1.68 1.95 1.46 1.02 2.21 2.06 -0.22 0.09 0.16 -0.56 -0.98 -0.48 -0.17 -0.25 -0.32 -0.19
311 || orf19.2770 || || || Ortholog of C. dubliniensis CD36 : Cd36_42220, C. parapsilosis CDC317 : CPAR2_500340, Debaryomyces hansenii CBS767 : DEHA2G17754g and Pichia stipitis Pignal : PICST_31424 || 1 1.92 1.84 1.67 1.16 2.03 2.08 -0.17 -0.07 0.18 -0.50 -1.08 -0.43 -0.35 -0.49 -0.43 -0.43
312 || orf19.2770 || || || Ortholog of C. dubliniensis CD36 : Cd36_42220, C. parapsilosis CDC317 : CPAR2_500340, Debaryomyces hansenii CBS767 : DEHA2G17754g and Pichia stipitis Pignal : PICST_31424 || 1 1.76 1.83 1.61 0.99 2.21 1.91 -0.25 -0.11 0.25 -0.41 -1.17 -0.62 -0.42 -0.38 -0.41 -0.62
313 || orf19.2770 || || || Ortholog of C. dubliniensis CD36 : Cd36_42220, C. parapsilosis CDC317 : CPAR2_500340, Debaryomyces hansenii CBS767 : DEHA2G17754g and Pichia stipitis Pignal : PICST_31424 || 1 1.67 1.82 0.62 1.07 2.10 1.97 -0.29 -0.03 0.21 -0.60 -1.25 -0.79 -0.41 -0.58 -0.38 -0.98
314 || orf19.6731.1 || || || Ortholog of C. dubliniensis CD36 : Cd36_87460, C. parapsilosis CDC317 : CPAR2_808260, Debaryomyces hansenii CBS767 : DEHA2F07084g and Pichia stipitis Pignal : psti_CGOB_00185 || 1 0.66 0.85 0.53 0.38 1.00 1.02 0.36 0.22 -0.09 -0.44 0.13 -0.28 0.07 -0.41 -0.17 -0.53
315 || orf19.4241 || || || Protein of unknown function; transcript detected on high-resolution tiling arrays || 1 0.58 0.51 0.00 0.16 0.64 0.68 0.21 0.20 -0.11 -0.03 0.09 -0.02 -0.17 -0.10 -0.01 -0.34
316 || orf19.3445 || HOC1 || || Protein with similarity to mannosyltransferases; similar to S. cerevisiae Hoc1p and C. albicans Och1p || 1 0.51 0.58 0.41 0.46 0.89 0.60 -0.40 -0.10 -0.11 0.21 -0.57 -0.16 -0.03 0.02 -0.58 -0.62
317 || orf19.3303 || || || Ortholog(s) have tRNA methyltransferase activity, role in tRNA methylation, wybutosine biosynthetic process and cytosol, mitochondrion, nucleus localization || 1 0.28 0.89 0.40 0.34 0.84 0.52 -0.48 -0.39 0.31 0.20 -0.25 -0.21 0.47 -0.01 0.04 -0.42
318 || orf19.7523 || MKC1 || || MAP kinase; role in biofilm formation, contact-induced invasive filamentation, systemic virulence in mouse, cell wall structure/maintenance, caspofungin response; phosphorylated on surface contact, membrane perturbation, or cell wall stress || 1 0.27 0.71 0.61 0.51 0.96 0.48 -0.49 -0.48 0.43 -0.10 -0.21 0.04 0.75 -0.46 0.19 -0.14
319 || orf19.459 || ADP1 || || Putative PDR-subfamily ABC transporter; similar to WHITE subfamily proteins; gene used for strain identification by multilocus sequence typing || 1 0.32 0.66 0.99 1.01 0.86 0.69 -0.43 -0.60 0.24 -0.49 -0.62 -0.14 0.44 -0.34 0.31 -0.32
320 || orf19.7350 || RCT1 || || Fluconazole-induced protein; Ras1, Cyr1 repressed and Efg1 induced; regulated by Nrg1, Tup1, Tbf1, Ssn6; induced in oralpharyngeal candidasis; rat catheter biofilm repressed || 1 1.04 1.24 1.48 1.61 1.34 1.38 -0.32 -0.92 -0.10 -0.12 -0.45 -0.46 0.45 -0.76 0.55 -0.26
321 || orf19.7108 || || || D-ribulose-5-phosphate 3-epimerase; stationary phase enriched protein || 1 0.39 0.44 0.44 0.63 0.20 0.65 -0.30 -0.39 0.20 -0.11 -0.30 -0.14 0.35 -0.44 0.15 -0.14
322 || orf19.4078 || || || Ortholog(s) have role in U1 snRNA 3'-end processing, U4 snRNA 3'-end processing and U5 snRNA 3'-end processing, more || 1 0.99 1.08 0.59 0.92 0.73 1.01 -0.35 -0.56 0.39 -0.16 -0.28 -0.49 0.65 -0.52 0.07 -0.69
323 || orf19.3626 || || || Ortholog(s) have cytosol, nucleus localization || 1 0.36 0.49 0.38 0.46 0.50 0.71 -0.26 -0.70 0.05 0.18 -0.23 -0.04 0.26 -0.17 -0.06 -0.48
324 || orf19.3440 || FRP5 || || Protein with a GPR1/FUN34/yaaH family domain; flucytosine repressed || 1 -0.08 0.27 1.18 1.03 0.23 1.88 -0.10 -0.27 0.72 -0.16 -0.28 0.11 0.20 0.37 -0.14 -0.04
325 || orf19.6685 || ISY1 || || Putative pre-mRNA-splicing factor; mutation confers resistance to 5-fluorocytosine (5-FC); rat catheter biofilm induced || 1 0.37 0.34 0.85 1.32 0.60 1.57 -0.17 -0.38 0.57 -0.25 -0.74 0.10 0.26 0.44 -0.11 -0.14
326 || orf19.4234 || || || Protein of unknown function; Hap43-induced gene; Ctr86 ortholog in S. cerveisiae is essential; Spider biofilm induced || 1 -0.07 0.17 0.82 0.68 0.39 1.07 -0.29 -0.43 0.16 -0.18 -0.39 0.28 0.21 0.43 0.00 -0.28
327 || orf19.3852 || || || Has domain(s) with predicted carbohydrate binding, catalytic activity and role in carbohydrate metabolic process || 1 0.17 0.66 1.61 1.35 0.89 2.00 -0.55 -0.64 0.42 -0.45 -0.79 -0.04 0.17 -0.07 -0.54 -0.55
328 || orf19.4801 || || || Ortholog(s) have tRNA dimethylallyltransferase activity, role in tRNA modification and cytosol, mitochondrion, nucleolus localization || 1 0.44 0.53 0.84 0.65 0.96 1.30 0.06 -0.51 0.24 0.39 -0.41 -0.36 0.09 -0.01 -0.16 0.17
329 || orf19.1589 || || || Putative transcription factor component of the core factor (CF) rDNA transcription factor complex; Spider biofilm induced || 1 0.25 0.34 0.89 0.63 0.89 1.51 -0.25 -0.31 0.17 -0.01 -0.16 -0.23 0.20 0.04 -0.03 -0.40
330 || orf19.1708 || || || Protein of unknown function; Spider biofilm induced || 1 0.53 0.62 1.44 1.25 0.94 1.61 -0.41 -0.43 0.97 -0.12 -0.19 -0.10 0.47 0.00 0.09 -0.14
331 || orf19.4326 || || || Ortholog(s) have role in mRNA cis splicing, via spliceosome, maturation of 5S rRNA and U4/U6 x U5 tri-snRNP complex localization || 1 0.13 0.61 0.78 0.60 0.90 1.25 -0.05 -0.19 0.81 -0.01 -0.25 -0.39 0.40 -0.01 0.23 -0.27
332 || orf19.5573 || || || Protein of unknown function; expression downregulated in an ssr1 null mutant || 1 0.31 0.85 0.85 0.68 1.13 1.41 0.23 -0.30 0.46 0.07 -0.30 -0.03 0.45 0.36 0.12 0.08
333 || orf19.151 || TPO5 || || Putative polyamine transporter; mutation confers hypersensitivity to toxic ergosterol analog; hyphal induced; macrophage induced || 1 0.24 0.40 0.67 0.32 0.51 0.80 -0.04 -0.26 0.15 0.20 -0.00 0.16 0.45 0.17 0.12 -0.11
334 || orf19.3186 || || || Ortholog of Candida albicans WO-1 : CAWG_04571 || 1 0.10 0.38 0.92 1.30 0.73 1.04 -0.14 -0.33 0.20 -0.19 -0.06 0.19 0.65 -0.08 -0.28 -0.26
335 || orf19.2559 || CDC4 || || F-box subunit of SCF(CDC4) ubiquitin ligase; functional homolog of S. cerevisiae Cdc4; mutation/depletion causes hyperfilamentation; Sol1 is a substrate of SCF-Cdc4; Spider biofilm induced || 1 0.31 0.34 0.67 0.67 0.52 0.65 -0.43 -0.23 0.15 -0.16 0.19 -0.30 0.55 -0.21 -0.30 -0.33
336 || orf19.5391 || || || Predicted RNA splicing and ER to Golgi transport protein; Hap43-induced gene || 1 0.30 0.55 0.62 0.82 0.76 0.67 -0.19 -0.08 0.44 0.03 -0.05 -0.13 0.64 -0.16 -0.12 -0.71
337 || orf19.5977 || CEM1 || || Protein similar to S. cerevisiae Cem1p, an acyl carrier protein involved in fatty acid biosynthesis; likely to be essential for growth, based on an insertional mutagenesis strategy || 1 0.29 0.20 0.71 0.70 0.56 0.67 -0.04 -0.06 -0.00 0.08 -0.41 -0.17 0.47 0.06 -0.20 -0.44
338 || orf19.3227 || FTH2 || || Putative iron transporter; similar to S. cerevisiae Fth1p || 1 0.58 0.85 0.86 0.76 0.62 0.54 -0.41 -0.07 0.40 0.65 -0.26 0.09 0.79 -0.51 -0.24 -0.49
339 || orf19.7121 || || || Protein of unknown function; Spider biofilm repressed || 1 0.19 0.64 0.45 0.34 0.61 0.52 -0.41 -0.12 0.60 0.42 -0.29 -0.09 0.59 -0.24 -0.13 -0.32
340 || orf19.4214 || || || Ortholog of Candida albicans WO-1 : CAWG_05313 || 1 0.21 0.93 1.16 1.10 0.73 1.07 -0.60 -0.26 1.15 0.54 -0.57 -0.42 0.82 -0.64 -0.55 -0.32
341 || orf19.1920 || || || Ortholog of C. dubliniensis CD36 : Cd36_15040 || 1 0.09 0.69 0.95 1.64 0.54 0.90 -0.80 -0.70 0.60 0.92 -0.71 -0.63 0.69 -0.89 -0.56 -0.62
342 || orf19.850 || || || Ortholog(s) have protein-N-terminal asparagine amidohydrolase activity, protein-N-terminal glutamine amidohydrolase activity and role in cellular protein modification process, protein catabolic process || 1 0.09 0.73 0.88 1.04 0.52 0.52 -0.47 -0.48 0.38 0.12 -0.66 -0.41 0.60 -0.22 -0.23 -0.33
343 || orf19.6355 || || || Ortholog(s) have role in ribosome biogenesis and cytosol, nucleolus localization || 1 0.16 0.63 0.80 0.75 0.77 0.98 -0.16 -0.40 0.60 0.42 -0.26 -0.56 0.56 0.03 -0.38 -0.40
344 || orf19.6686 || ENP2 || || Putative nucleolar protein; essential; heterozygous mutation confers resistance to 5-fluorocytosine (5-FC), 5-fluorouracil (5-FU), and tubercidin (7-deazaadenosine); Hap43-induced; Spider biofilm induced || 1 0.24 0.53 1.58 1.21 0.70 1.74 -0.21 -0.68 0.93 0.83 -0.41 -0.95 0.65 0.24 -0.48 -0.23
345 || orf19.7088 || || || Ortholog(s) have single-stranded telomeric DNA binding activity, role in regulation of translational fidelity, telomere maintenance, threonylcarbamoyladenosine metabolic process and cytosol, nucleus localization || 1 0.06 0.25 0.81 0.74 0.11 0.85 -0.27 -0.44 0.14 0.19 -0.46 -0.42 0.25 -0.11 -0.12 -0.25
346 || orf19.3088 || || || bZIP transcription factor; possibly transcriptionally regulated upon hyphal formation; Hap43; F-12/CO2 early biofilm induced; Spider biofilm induced || 1 0.25 0.51 0.89 0.65 0.39 0.94 -0.13 -0.27 0.22 0.25 -0.25 -0.62 0.41 -0.54 -0.19 -0.51
347 || orf19.3275 || || || Ortholog of C. dubliniensis CD36 : Cd36_25870, C. parapsilosis CDC317 : CPAR2_804000, Candida tenuis NRRL Y-1498 : CANTEDRAFT_115661 and Debaryomyces hansenii CBS767 : DEHA2B05852g || 1 0.46 0.67 1.18 0.50 0.74 1.19 -0.12 -0.29 0.19 -0.06 -0.24 -0.38 0.79 -0.43 -0.26 -0.27
348 || orf19.3903 || MRV3 || || Ortholog of Candida albicans WO-1 : CAWG_04793 || 1 0.45 0.69 1.16 0.59 0.81 1.46 -0.05 -0.28 0.99 -0.02 -0.52 -0.29 0.80 -0.72 -0.45 0.08
349 || orf19.3724 || || || Ortholog(s) have role in endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA and LSU-rRNA), more || 1 0.36 0.14 1.02 0.85 0.28 1.35 -0.41 -0.23 0.52 0.01 -0.42 -0.23 0.20 -0.29 -0.56 0.23
350 || orf19.3109 || || || Ortholog of C. dubliniensis CD36 : Cd36_46470, C. parapsilosis CDC317 : CPAR2_500900, Debaryomyces hansenii CBS767 : DEHA2B15730g and Candida tropicalis MYA-3404 : CTRG_03755 || 1 0.29 0.45 1.63 1.43 0.48 1.20 -0.45 0.23 0.46 0.02 -0.21 -0.49 0.59 -0.14 -0.31 0.04
351 || orf19.5299 || ECM1 || || Putative pre-ribosomal factor; decreased mRNA abundance observed in cyr1 homozygous mutant hyphae; induced by heavy metal (cadmium) stress; Hog1p regulated || 1 0.45 0.39 1.33 1.40 0.80 2.05 0.13 0.27 0.28 0.58 0.95 -0.21 0.14 0.57 -0.22 -0.57
352 || orf19.5190 || || || Ortholog of Candida albicans WO-1 : CAWG_05610 || 1 0.16 0.21 0.72 0.69 0.89 1.39 -0.24 -0.05 0.31 0.40 0.45 -0.30 0.56 0.29 0.04 -0.63
353 || orf19.6731.1 || || || Ortholog of C. dubliniensis CD36 : Cd36_87460, C. parapsilosis CDC317 : CPAR2_808260, Debaryomyces hansenii CBS767 : DEHA2F07084g and Pichia stipitis Pignal : psti_CGOB_00185 || 1 -0.13 0.05 0.62 0.53 0.45 0.98 -0.20 -0.05 0.05 0.01 -0.15 0.16 0.09 0.02 -0.26 -0.61
354 || orf19.3852 || || || Has domain(s) with predicted carbohydrate binding, catalytic activity and role in carbohydrate metabolic process || 1 0.50 0.04 1.42 1.09 0.53 2.19 -0.15 -0.33 -0.67 -0.02 -0.44 0.38 -0.28 0.27 -0.31
355 || orf19.5446 || || || Putative protein of unknown function; transcript is upregulated in clinical isolates from HIV+ patients with oral candidiasis; regulated by Ssn6 || 1 0.25 -0.06 0.48 0.35 1.27 -0.14 -0.19 -0.18 -0.01 0.02 0.42 -0.06
356 || orf19.275 || || || Ortholog(s) have RNA binding, ribonuclease MRP activity, ribonuclease P activity, role in intronic box C/D snoRNA processing, mRNA cleavage and endoplasmic reticulum, nucleolar ribonuclease P complex, ribonuclease MRP complex localization || 1 0.03 0.03 0.55 0.83 0.19 0.94 -0.23 -0.12 -0.04 0.23 -0.26 0.16 0.23 -0.11 -0.03 -0.18
357 || orf19.2488 || FAL1 || || eIF4A subfamily of DEAD-box ATP-dependent RNA helicases; predicted nucleolar protein required for maturation of 18S rRNA; Spider biofilm induced || 1 0.09 0.29 0.83 0.73 0.44 1.49 -0.54 -0.31 -0.25 0.69 -0.14 0.01 -0.06 0.10 -0.10 -0.19
358 || orf19.3578 || || || Ortholog of C. dubliniensis CD36 : Cd36_19950, C. parapsilosis CDC317 : CPAR2_104135, Candida tenuis NRRL Y-1498 : cten_CGOB_00075 and Debaryomyces hansenii CBS767 : DEHA2F07964g || 1 0.07 0.19 0.62 0.71 -0.04 0.85 -0.24 -0.00 0.14 0.41 -0.19 0.32 0.03 0.33 0.08 -0.48
359 || orf19.1318 || || || Ortholog of C. dubliniensis CD36 : Cd36_43350, C. parapsilosis CDC317 : CPAR2_403560, Debaryomyces hansenii CBS767 : DEHA2A08250g and Pichia stipitis Pignal : PICST_29838 || 1 0.27 0.35 0.91 0.62 0.51 0.60 -0.02 -0.19 -0.36 0.18 -0.21 0.25 0.19 0.17 0.19 -0.30
360 || orf19.4895 || || || Ortholog of C. dubliniensis CD36 : Cd36_09650, C. parapsilosis CDC317 : CPAR2_805060, Candida tenuis NRRL Y-1498 : CANTEDRAFT_95780 and Debaryomyces hansenii CBS767 : DEHA2B12320g || 1 0.47 0.45 1.07 1.01 0.50 0.71 0.21 0.11 -0.18 0.27 -0.10 0.09 0.53 0.20 0.36 -0.40
361 || orf19.4634 || || || Protein required for thiolation of uridine at wobble position of Gln, Lys, and Glu tRNAs; has a role in urmylation; S. cerevisiae ortholog has a role in invasive and pseudohyphal growth || 1 0.27 0.15 0.96 0.66 0.43 1.17 0.08 -0.15 -0.08 0.33 -0.17 0.02 0.31 0.22 0.35 -0.27
362 || orf19.6652 || DBP8 || || Protein similar to S. cerevisiae Dbp8p, an ATP-dependent helicase involved in rRNA processing; oxidative stress-repressed via Cap1p; flucytosine repressed; likely to be essential for growth, based on insertional mutagenesis || 1 0.30 0.38 1.09 0.54 0.56 1.27 0.18 0.00 -0.16 0.24 -0.34 -0.34 0.19 0.08 0.21 -0.06
363 || orf19.4600 || || || Protein of unknown function; possible mitochondrial protein; Spider biofilm induced || 1 0.27 0.18 1.06 0.76 0.19 0.71 0.17 0.08 0.12 0.60 -0.39 -0.11 -0.07 0.39 0.08 -0.17
364 || orf19.3287 || BUD22 || || Protein with a predicted role in 18S rRNA maturation and small ribosomal subunit biogenesis; repressed in core stress response; repressed by prostaglandins || 1 0.31 0.47 1.98 1.61 0.43 1.52 0.03 0.19 0.45 0.62 -0.36 -0.32 0.28 0.13 -0.19 -0.84
365 || orf19.87 || GPX1 || || Putative thiol peroxidase; rat catheter and Spider biofilm induced || 1 0.18 0.36 1.23 1.15 0.31 0.71 0.03 0.08 0.19 1.01 0.05 -0.38 0.19 0.23 -0.10 -0.54
366 || orf19.1966 || BUD23 || || Putative methyltransferase; Hap43-induced; repressed by prostaglandins || 1 0.32 0.12 0.70 0.78 0.59 0.75 0.12 0.03 -0.09 0.92 -0.11 -0.14 0.19 -0.16 0.08 0.08
367 || orf19.6347 || || || Pre-mRNA splicing factor; important for catalytic step II of pre-mRNA splicing; possible role in cell cycle progression; Spider biofilm induced || 1 -0.13 0.42 1.70 1.05 0.72 1.06 -0.34 -0.80 0.30 0.29 -0.22 -0.22 0.35 0.05 -0.06 0.51
368 || orf19.2604 || || || S. pombe ortholog SPAC2C4.06c is a predicted tRNA (cytosine-5-)-methyltransferase; Spider biofilm induced || 1 0.15 0.25 1.23 0.52 0.42 1.19 -0.60 -0.49 -0.04 -0.26 -0.12 -0.67 0.50 -0.14 -0.05 -0.66
369 || orf19.773 || || || Protein similar to S. cerevisiae Rsa3 predicted nucleolar protein involved in maturation of pre-60S ribosomal particles; rat catheter and Spider biofilm induced || 1 0.46 0.51 0.69 0.80 0.36 0.42 0.22 -0.02 -0.33 0.07 -0.47 -0.22 0.55 -0.34 -0.12 -0.70
370 || orf19.93 || || || Putative mitochondrial intermembrane space protein; colony morphology-related gene regulation by Ssn6; regulated by Sef1, Sfu1, and Hap43; Spider biofilm repressed; rat catheter biofilm induced || 1 1.45 1.45 0.77 1.18 0.95 0.89 0.10 0.06 -0.15 0.39 -0.56 -0.93 -0.78 -1.13 -0.16 -1.31
371 || orf19.3210 || || || Predicted protein of unknown function; Plc1-regulated || 1 0.83 1.84 0.41 1.00 0.26 0.81 -0.02 0.00 0.37 0.06 -0.38 -0.39 0.45 -0.29 0.07 -0.55
372 || orf19.4749 || || || Protein of unknown function; hyphal-induced expression, regulated by Cyr1, Ras1, Efg1; Hap43-induced gene; Spider biofilm induced || 1 0.63 1.13 0.41 1.03 0.79 0.02 -0.03 0.39 0.05 0.14 -0.12 -0.66 0.29 -0.18 -0.27 -1.13
373 || orf19.4573 || ZCF26 || || Zn2-Cys6 transcription factor of unknown function; induced by alpha pheromone in SpiderM medium || 1 1.97 2.03 1.34 1.27 0.61 0.27 0.44 0.83 0.83 0.59 -1.07 -1.12 0.72 -0.13 0.41 -1.80
374 || orf19.5270 || || || Protein of unknown function; rat catheter biofilm induced || 1 1.02 1.02 0.47 0.69 0.23 0.01 0.20 0.14 0.07 -0.10 -0.75 -0.58 0.27 -0.08 0.62 -1.20
375 || orf19.7279 || NIT2 || || Putative carbon-nitrogen hydrolase; rat catheter biofilm repressed || 1 1.15 1.12 0.59 0.34 0.54 0.99 0.06 0.09 0.46 -0.10 -1.38 -0.43 -0.03 -0.18 -0.09 -1.00
376 || orf19.2346 || || || Putative protein of unknown function, transcription is positively regulated by Tbf1p || 1 0.64 0.68 0.53 0.31 0.28 0.22 0.07 -0.02 0.38 -0.00 -0.81 -0.26 -0.21 0.44 0.11 -0.43
377 || orf19.7281 || PDK2 || || Putative pyruvate dehydrogenase kinase; mutation confers hypersensitivity to amphotericin B || 1 0.64 0.59 0.52 0.47 0.12 0.21 -0.03 -0.13 0.13 -0.14 -0.39 0.07 0.12 0.05 0.58 -0.12
378 || orf19.2747 || RGT1 || || Zn(II)2Cys6 transcription factor; transcriptional repressor involved in the regulation of glucose transporter genes; ortholog of S. cerevisiae Rgt1; mutants display decreased colonization of mouse kidneys || 1 1.11 1.13 1.09 0.81 1.03 0.42 -0.02 0.11 0.27 0.05 -0.78 0.02 0.39 -0.51 0.97 -0.54
379 || orf19.2851 || || || Putative ornithine transport protein; localized to the mitochondrial membrane || 1 0.38 0.54 0.98 1.06 1.18 0.66 -0.06 0.07 0.63 -0.47 -0.21 -0.36 0.66 -0.67 0.08 -0.44
380 || orf19.6049 || || || Ortholog(s) have protein kinase activator activity, role in protein phosphorylation, regulation of cytokinesis and chromosome passenger complex, kinetochore microtubule, spindle midzone localization || 1 0.40 0.56 0.68 0.29 1.12 0.73 0.58 0.05 0.23 -0.16 0.15 -0.25 0.78 -0.48 0.19 -0.48
381 || orf19.5573 || || || Protein of unknown function; expression downregulated in an ssr1 null mutant || 1 1.45 1.31 0.64 0.81 1.31 0.80 0.69 -0.10 0.26 -0.33 -0.19 -0.33 1.22 0.05 -1.46
382 || orf19.4778 || LYS142 || || Zn(II)2Cys6 transcription factor; has similarity to S. cerevisiae Lys14, involved in the regulation of lysine biosynthesis genes; fungal-specific || 1 0.23 0.67 0.59 0.26 0.19 0.40 0.09 -0.03 0.30 -0.37 -0.02 0.05 0.35 -0.15 0.20 -0.39
383 || orf19.842 || ASR3 || || Adenylyl cyclase and stress responsive protein; induced in cyr1 or ras1 mutant; Spider biofilm induced || 1 0.70 0.91 1.03 0.85 0.82 1.42 0.42 0.05 0.89 -0.28 -0.48 0.11 0.13 -0.95 1.29 -0.66
384 || orf19.842 || ASR3 || || Adenylyl cyclase and stress responsive protein; induced in cyr1 or ras1 mutant; Spider biofilm induced || 1 0.77 0.72 0.77 0.34 0.64 0.85 0.34 -0.06 0.46 -0.53 -0.70 -0.43 0.10 -1.45 1.09 -0.84
385 || orf19.3107 || || || Ortholog of C. dubliniensis CD36 : Cd36_46490, Pichia stipitis Pignal : PICST_33598, Spathaspora passalidarum NRRL Y-27907 : spas_CGOB_00037 and Candida tropicalis MYA-3404 : CTRG_03758 || 1 0.41 0.74 0.37 0.75 0.88 0.58 0.48 0.16 0.57 0.01 -0.51 -0.82 0.04 -0.90 0.30 -0.62
386 || orf19.163 || PAN6 || || Ortholog(s) have pantoate-beta-alanine ligase activity, role in pantothenate biosynthetic process and cytosol, nucleus localization || 1 0.41 0.45 0.58 0.28 0.32 0.70 0.49 0.56 0.67 -0.05 -0.17 -0.41 0.51 -0.24 0.30 -0.39
387 || orf19.773 || || || Protein similar to S. cerevisiae Rsa3 predicted nucleolar protein involved in maturation of pre-60S ribosomal particles; rat catheter and Spider biofilm induced || 1 0.69 0.30 0.62 0.30 0.43 0.74 0.49 0.18 -0.24 0.30 -0.33 -0.26 0.33 0.12 0.47 -0.57
388 || orf19.5845 || RNR3 || || Putative ribonucleotide reductase large subunit; transcript induced in low iron; rat catheter and Spider biofilm induced || 1 1.12 1.16 -0.04 0.55 1.08 1.79 -0.09 -0.37 0.29 0.85 -1.37 -0.38 0.11 0.42 0.81 -0.67
389 || orf19.2474 || PRC3 || || Putative carboxypeptidase Y precursor; transcript regulated by Nrg1 and Mig1; regulated by Gcn2 and Gcn4 || 1 0.32 0.50 1.00 0.82 0.20 0.65 0.48 -0.08 0.51 -0.36 -0.77 -0.16 0.64 0.18 0.07 -0.57
390 || orf19.6478 || YCF1 || || Putative glutathione S-conjugate transporter; MRP/CFTR-subfamily, ABC type transporter; human neutrophil-induced; oxidative stress-induced via Cap1; possible association with multidrug resistance; possibly essential; Spider biofilm induced || 1 0.07 0.26 0.19 0.29 0.06 0.08 0.12 -0.16 0.23 -0.25 -0.38 0.03 0.23 0.23 -0.05 -0.43
391 || orf19.7209 || || || Putative Rho GDP dissociation inhibitor; induced by nitric oxide independent of Yhb1p || 1 0.92 0.72 0.55 1.74 0.50 0.20 0.00 -0.16 -0.16 0.35 0.18 0.31 -0.09 0.48 -0.00 -2.63
392 || orf19.4566 || || || Protein similar to S. cerevisiae Rot1p, which has roles in cytoskeletal dynamics and cell wall biosynthesis; predicted Kex2p substrate || 1 0.81 0.45 1.17 1.18 -0.01 1.28 0.33 0.05 0.89 -0.68 -0.21 -0.52 -0.04 0.29 -0.01 -1.75
393 || orf19.4463 || || || Ortholog of Candida albicans WO-1 : CAWG_01004 || 1 0.90 0.46 1.11 1.22 -0.08 0.82 0.34 0.02 0.75 -0.02 -0.15 -0.06 -0.27 0.84 0.37
394 || orf19.4516 || || || Ortholog(s) have tetrahydrofolylpolyglutamate synthase activity, role in one-carbon metabolic process, regulation of DNA methylation and cytosol, mitochondrion, nucleus localization || 1 0.52 0.59 0.68 0.90 0.33 0.14 0.06 0.15 0.09 0.39 0.06 0.24 0.37 0.21 0.06 -0.57
395 || orf19.2711.1 || MED20 || || Subunit of the RNA polymerase II mediator complex; involved in control of filamentous growth and Spider biofilm formation; rat catheter biofilm repressed || 1 0.25 0.33 0.76 0.74 0.21 0.44 -0.16 -0.01 0.18 0.20 0.06 0.43 0.30 0.19 0.17 -0.60
396 || orf19.1450 || || || Ortholog of C. dubliniensis CD36 : Cd36_16320, Candida tropicalis MYA-3404 : CTRG_01238 and Candida albicans WO-1 : CAWG_03918 || 1 0.33 0.34 1.13 1.98 0.59 0.87 -0.04 0.57 0.20 -0.10 0.24 0.38 0.37 0.99 0.18 -1.80
397 || orf19.7609 || PGA11 || || Putative GPI-anchored protein || 1 0.25 0.54 0.54 0.63 0.45 0.23 -0.18 -0.13 0.44 -0.22 0.09 0.54 0.28 0.09 -0.05 -1.08
398 || orf19.5167 || IFM1 || || Putative mitochondrial translation initiation factor; transcript regulated by Nrg1, Mig1, and Tup1 || 1 0.07 0.49 0.76 1.11 0.46 0.43 -0.11 -0.14 0.77 0.18 -0.54 0.34 0.61 -0.41 -0.06 -1.34
399 || orf19.2715 || RPC53 || || Ortholog(s) have RNA polymerase III activity, role in tRNA transcription from RNA polymerase III promoter and DNA-directed RNA polymerase III complex localization || 1 0.01 0.31 0.64 0.96 0.21 0.47 -0.32 -0.25 0.28 0.06 -0.21 0.04 0.14 -0.14 -0.30 -0.73
400 || orf19.3049 || || || Ortholog(s) have protein kinase activity, role in activation of bipolar cell growth, ascospore wall assembly, protein phosphorylation and cell division site, cytosol, nucleus, prospore membrane localization || 1 0.17 0.26 1.25 1.12 -0.05 1.17 -0.14 0.20 0.47 0.12 0.17 -0.09 0.44 -0.18 -0.13 -0.93
401 || orf19.5896 || || || Protein of unknown function; induced by alpha pheromone in SpiderM medium || 1 -0.14 0.66 1.22 -0.27 -0.44 0.00 -0.02 0.63 -0.09 0.50 -0.12 -1.42
402 || orf19.4011 || || || Similar to S. pombe mug180, a predicted esterase/lipase; highly induced during chlamydospore formation in both C. albicans and C. dubliniensis; flow model biofilm induced || 1 0.18 0.62 0.59 0.71 0.48 0.56 -0.57 0.03 0.19 0.23 0.09 0.30 0.03 0.23 0.25 -0.22
403 || orf19.3303 || || || Ortholog(s) have tRNA methyltransferase activity, role in tRNA methylation, wybutosine biosynthetic process and cytosol, mitochondrion, nucleus localization || 1 0.10 -0.09 0.71 0.64 0.45 0.18 0.09 0.34 -0.35 0.07 -0.22 0.03 -0.01 -0.28 0.08 0.08
404 || orf19.6356 || || || Ortholog(s) have role in mRNA splicing, via spliceosome and U4/U6 x U5 tri-snRNP complex localization || 1 -0.07 -0.14 1.27 0.62 0.44 0.33 0.05 0.12 -0.20 -0.04 -0.34 0.07 -0.08 -0.08 0.24 0.03
405 || orf19.4691 || MRV1 || || Ortholog of Candida albicans WO-1 : CAWG_03682 || 1 -0.09 0.19 1.16 0.91 0.72 0.38 0.13 0.01 -0.05 -0.40 -0.40 -0.07 -0.21 -0.21 0.07 0.25
406 || orf19.555 || || || Protein similar to S. cerevisiae Cis3p, which has a role cell-wall-related processes; predicted Kex2p substrate; possibly an essential gene, disruptants not obtained by UAU1 method || 1 0.00 0.34 1.10 1.32 0.94 0.75 -0.03 -0.12 0.35 -0.22 -0.44 0.27 -0.25 0.24 0.17 0.02
407 || orf19.5472 || || || Protein of unknown function || 1 0.07 -0.10 0.96 2.22 1.75 0.93 0.15 0.04 0.65 -0.00 -0.38 0.31 -0.30 -0.50 0.14 0.46
408 || orf19.3908 || MRV8 || || Protein of unknown function; Spider biofilm induced || 1 -0.12 0.09 0.80 0.87 0.94 0.52 -0.29 -0.09 0.12 0.04 -0.28 -0.03 -0.17 -0.62 -0.04 -0.07
409 || orf19.7403 || || || Ortholog of S. cerevisiae : YML020W, C. glabrata CBS138 : CAGL0J10538g, C. dubliniensis CD36 : Cd36_86190, C. parapsilosis CDC317 : CPAR2_404740 and Candida tenuis NRRL Y-1498 : CANTEDRAFT_107670 || 1 0.03 0.07 0.43 0.71 0.82 0.61 -0.43 -0.26 0.20 -0.12 -0.21 0.11 -0.54 -0.11 0.05 0.24
410 || orf19.3833 || || || Putative DNA-binding transcription factor; decreased transcription is observed upon fluphenazine treatment; possibly an essential gene, disruptants not obtained by UAU1 method; Hap43p-induced gene || 1 -0.06 -0.09 0.46 0.25 0.71 0.95 -0.25 0.10 -0.05 -0.43 0.07 0.41 -0.23 -0.38 0.14 0.11
411 || orf19.1769 || || || Ortholog(s) have G-protein beta/gamma-subunit complex binding, actin binding activity, role in positive regulation of transcription from RNA polymerase II promoter by pheromones, protein folding and cytoplasm localization || 1 -0.15 0.06 0.59 0.36 0.78 0.74 -0.06 0.10 -0.31 -0.16 0.22 0.17 -0.25 0.12 0.28 0.20
412 || orf19.1953 || || || Predicted protein of unknown function; merged with orf19.1952 in Assembly 21 || 1 -0.38 -0.15 0.47 0.34 0.48 0.77 0.01 0.04 -0.07 -0.41 -0.09 0.31 -0.06 0.16 0.25 0.04
413 || orf19.2528 || || || Putative RNA polymerase III transcription factor (TFIIIB) subunit; flucytosine repressed || 1 -0.19 -0.05 0.83 0.46 0.68 1.07 -0.27 0.23 0.09 -0.22 0.44 0.54 0.37 -0.06 0.17 0.19
414 || orf19.2190 || VRP1 || || Verprolin-related protein involved in actin cytoskeleton organization and polarized morphogenesis; interacts with Wal1p and Myo5p; downregulated upon adherence to polystyrene || 1 -0.22 -0.09 0.51 0.31 0.48 0.56 -0.03 -0.07 0.20 -0.10 0.03 0.28 0.27 0.05 0.25 -0.17
415 || orf19.3373 || || || Putative protein of unknown function; transcript upregulated in clinical isolates from HIV+ patients with oral candidiasis; Spider biofilm induced || 1 -0.11 0.00 0.90 0.85 0.34 0.86 0.13 0.36 0.06 -0.12 -0.06 0.51 0.34 0.29 0.60 0.03
416 || orf19.2423 || ZCF11 || || Zn(II)2Cys6 transcription factor; required for wild-type filamentous growth; mRNA binds She3 || 1 0.17 -0.28 0.57 0.56 0.46 0.59 0.23 0.16 0.15 -0.54 0.23 0.43 0.36 0.16 0.55 0.27
417 || orf19.7614 || || || Protein of unknown function; Hap43-induced gene; mutant is viable || 1 -0.47 0.38 1.36 1.17 1.18 0.57 -0.06 -0.21 0.26 0.86 0.26 -0.05
418 || orf19.6267 || || || Ortholog of C. dubliniensis CD36 : Cd36_06020, C. parapsilosis CDC317 : CPAR2_803380, Candida tenuis NRRL Y-1498 : CANTEDRAFT_91858 and Pichia stipitis Pignal : PICST_30337 || 1 -0.20 0.58 1.43 1.32 1.86 0.31 -0.17 -0.55 0.03 -0.12 0.82 -0.12 0.26
419 || orf19.6338 || || || Ortholog of Candida albicans WO-1 : CAWG_05352 || 1 -0.04 -0.28 1.18 1.56 1.42 0.99 -0.37 -0.11 0.40 -0.32 0.61 0.89 -0.43 -0.33 -0.46 -0.53
420 || orf19.4442 || ALG9 || || Putative mannosyltransferase; similar to S. cerevisiae Alg9p; has HKEXRF motif || 1 -0.12 0.68 0.60 0.66 0.07 0.08 0.04 0.02 0.62 0.25 0.09 0.08 -0.13 0.05 0.05 0.01
421 || orf19.4682 || HGT17 || || Putative MFS family glucose transporter; 20 members in C. albicans; 12 probable membrane-spanning segments; induced at low (0.2%, compared to 2%) glucose in rich media; Spider biofilm induced || 1 -0.06 0.75 0.84 0.56 0.46 0.00 -0.00 0.05 0.45 0.23 -0.11 0.01 -0.04 -0.10 0.04 -0.13
422 || orf19.4537 || || || Ortholog(s) have RNA polymerase II core binding, RNA polymerase II regulatory region DNA binding, core RNA polymerase II recruiting transcription factor activity || 1 0.36 0.49 0.51 0.60 0.21 -0.18 -0.14 0.15 -0.07 0.33 -0.27 0.44 0.24 0.03 -0.02 0.20
423 || orf19.6024 || || || Ortholog of C. dubliniensis CD36 : Cd36_00770, Candida tenuis NRRL Y-1498 : CANTEDRAFT_112621, Debaryomyces hansenii CBS767 : DEHA2D09812g and Pichia stipitis Pignal : PICST_61958 || 1 0.66 0.80 0.59 0.53 0.12 0.15 -0.20 -0.22 0.05 0.12 -0.40 0.51 0.57 0.31 0.01 0.52
424 || orf19.6151 || ARC15 || || Putative ARP2/3 complex subunit; mutation confers hypersensitivity to cytochalasin D || 1 0.35 0.57 0.79 0.68 0.40 0.11 -0.12 -0.05 0.27 0.18 -0.02 0.63 0.60 0.38 0.21 0.48
425 || orf19.4144 || || || Predicted protein kinase; clade-associated gene expression || 1 0.48 0.78 0.59 0.14 0.34 0.21 -0.06 0.04 0.61 0.13 -0.06 0.30 0.19 0.21 0.19 0.34
426 || orf19.331 || || || Ortholog(s) have S-adenosylmethionine-dependent methyltransferase activity, protein methyltransferase activity and role in peptidyl-glutamine methylation, regulation of translation || 1 1.46 1.54 0.61 0.65 0.21 -0.01 -0.39 0.02 0.88 0.30 0.02 0.46 0.90 0.16 -0.15 -0.30
427 || orf19.217 || || || Ortholog(s) have sequence-specific DNA binding activity || 1 0.66 1.06 0.87 0.17 0.10 0.52 -0.15 -0.19 0.07 0.24 -0.12 0.41 0.49 0.35 -0.24 -0.43
428 || orf19.6024 || || || Ortholog of C. dubliniensis CD36 : Cd36_00770, Candida tenuis NRRL Y-1498 : CANTEDRAFT_112621, Debaryomyces hansenii CBS767 : DEHA2D09812g and Pichia stipitis Pignal : PICST_61958 || 1 0.48 0.93 0.37 0.48 0.38 0.53 -0.02 -0.60 0.00 0.19 -0.51 0.28 0.49 0.47 -0.45 0.15
429 || orf19.4924 || || || Protein of unknown function; repressed in ssr1 mutant; Spider biofilm induced || 1 0.35 0.61 0.39 0.25 0.17 0.41 -0.06 -0.48 0.41 0.24 -0.34 0.28 0.14 0.30 -0.04 0.37
430 || orf19.6024 || || || Ortholog of C. dubliniensis CD36 : Cd36_00770, Candida tenuis NRRL Y-1498 : CANTEDRAFT_112621, Debaryomyces hansenii CBS767 : DEHA2D09812g and Pichia stipitis Pignal : PICST_61958 || 1 0.94 0.90 0.66 0.69 0.76 0.41 -0.41 -0.56 0.12 0.08 -0.54 0.24 0.92 -0.58 -0.13 0.20
431 || orf19.454 || SFL1 || || Transcription factor involved in negative regulation of morphogenesis, flocculation and virulence; induced in core caspofungin response; Spider biofilm induced || 1 0.11 0.26 0.95 0.59 0.25 0.54 -0.03 -0.29 0.11 -0.41 0.08 1.10 0.45 -0.26 0.30 0.28
432 || orf19.7098 || || || Putative protein of unknown function; Hap43-repressed; repressed by nitric oxide; Spider biofilm induced || 1 0.17 0.15 1.44 0.94 0.09 0.65 -0.01 -0.45 0.02 -0.95 0.33 0.53 0.08 -0.76 0.13 0.05
433 || orf19.1874 || || || Ortholog(s) have protein serine/threonine kinase activity, role in meiosis, meiotic recombination checkpoint, protein phosphorylation, regulation of linear element assembly and cytosol, linear element localization || 1 0.09 0.31 0.86 0.83 0.11 0.27 -0.12 -0.06 0.08 -0.16 0.00 0.51 -0.16 -0.79 -0.13 0.55
434 || orf19.513 || || || Protein with a DNA-binding domain, similar to S. cerevisiae meiosis-specific transcription factor Ndt80p || 1 0.66 0.59 1.21 0.75 0.27 0.87 0.44 0.67 0.21 -0.77 0.03 1.42 -0.46 -1.89 -0.05 0.83
435 || orf19.2517 || || || Predicted membrane transporter, member of the drug:proton antiporter (12 spanner) (DHA1) family, major facilitator superfamily (MFS) || 1 0.12 0.23 0.75 0.29 0.19 0.32 -0.03 0.14 0.09 0.05 -0.23 0.20 0.11 -0.37 -0.02 -0.05
436 || orf19.6044 || MOB2 || || Mob1/phocein domain protein of RAM signaling network; cell wall integrity; role in cell separation, cortical actin polarization; required for hyphal growth; phosphorylated by Cdc28 on hyphal induction; activates Cbk1; mRNA binds She3 || 1 0.39 0.34 0.89 0.67 0.10 0.33 -0.34 0.19 -0.16 0.16 -0.04 0.19 -0.00 -0.62 -0.22 -0.01
437 || orf19.3106 || MET16 || || Putative 3'-phosphoadenylsulfate reductase; sulfur amino acid metabolism; reports differ on regulation during biofilm formation; fungal-specific; possibly an essential gene, disruptants not obtained by UAU1 method; Hap43p-repressed gene || 1 0.54 0.21 0.86 0.71 0.10 0.04 -0.45 -0.33 0.45 0.20 0.03 0.16 0.58 -0.80 0.02 0.28
438 || orf19.4496 || || || Ortholog(s) have role in cellular calcium ion homeostasis and Golgi medial cisterna, cis-Golgi network, endoplasmic reticulum, fungal-type vacuole membrane localization || 1 0.66 0.25 0.72 0.64 0.12 0.01 -0.51 -0.23 0.41 0.14 0.11 0.24 0.24 -0.26 0.05 0.56
439 || orf19.5775 || || || Predicted ORF overlapping the Major Repeat Sequence on chromosome 6; member of a family encoded by FGR6-related genes in the RB2 repeat sequence; rat catheter biofilm repressed || 1 0.36 0.22 0.56 0.58 0.30 0.17 -0.26 0.06 0.48 0.00 -0.07 0.04 0.23 -0.40 -0.16 0.58
440 || orf19.2108 || SOD6 || || Copper- and zinc-containing superoxide dismutase; gene family includes SOD1, SOD4, SOD5, and SOD6; gene may contain an intron; Hap43-repressed; flow model and rat catheter biofilm induced || 1 0.64 0.70 1.07 1.03 0.49 0.65 0.07 0.16 0.72 -0.36 -0.13 0.14 0.07 -0.23 0.21 1.39
441 || orf19.1264 || CFL2 || || Oxidoreductase; iron utilization; Sfu1/Sef1/Hap43/Nrg1/Tup1/Rim101 regulated; alkaline/low iron/fluphenazine/ciclopirox olamine, flucytosine, fluconazole, Spider/flow model/rat catheter biofilm induced; caspofungin/amphotericin B repressed || 1 0.44 0.46 0.73 0.98 0.40 0.10 -0.04 0.17 -0.06 -0.46 -0.07 -0.03 0.45 -0.61 -0.05 1.01
442 || orf19.1724 || || || Protein of unknown function; induced by nitric oxide independent of Yhb1p || 1 0.34 0.85 0.58 1.16 0.21 0.68 -0.13 -0.12 0.33 -0.47 -0.56 -0.06 0.48 -1.17 -0.53 1.03
443 || orf19.7331 || FCY24 || || Putative transporter; more similar to S. cerevisiae Tpn1, which is a vitamin B6 transporter, than to purine-cytosine permeases; transcription is regulated by Nrg1; Spider biofilm induced || 1 0.20 0.35 0.68 0.49 0.40 0.39 0.23 0.24 0.46 -0.43 -0.59 0.42 0.16 -0.28 0.09 0.36
444 || orf19.4736 || || || Ortholog(s) have alkaline phosphatase activity and role in cellular response to cadmium ion, detoxification of cadmium ion, nicotinamide nucleotide metabolic process, protein dephosphorylation || 1 0.98 0.95 0.67 0.44 0.34 -0.14 1.03 0.66 0.41 -0.31 0.20 0.24 0.38 -0.88 -0.11 0.19
445 || orf19.7648 || || || Has domain(s) with predicted antiporter activity, drug transmembrane transporter activity, role in drug transmembrane transport and membrane localization || 1 0.72 0.65 0.60 1.11 0.70 0.24 0.66 0.56 -0.03 -0.45 0.13 0.14 0.45 -0.71 0.50 0.14
446 || orf19.2434 || NPL4 || || Putative ubiquitin-binding protein; regulated by Gcn2p and Gcn4p || 1 0.58 0.42 0.33 0.80 0.17 0.36 0.20 0.59 0.06 -0.04 0.33 0.64 0.04 -0.95 0.72 0.39
447 || orf19.3413 || FGR37 || || Protein lacking an ortholog in S. cerevisiae; transposon mutation affects filamentous growth || 1 0.84 0.90 0.51 0.89 0.25 0.47 0.46 0.88 0.71 0.61 0.09 0.11 -1.01 0.64 0.16
448 || orf19.119 || || || Ortholog(s) have protein C-terminal S-isoprenylcysteine carboxyl O-methyltransferase activity || 1 0.14 0.60 0.31 0.28 0.13 0.19 0.33 0.55 0.44 0.21 0.20 0.27 -0.08 0.16 -0.25 0.36
449 || orf19.6949 || || || Ortholog of Candida albicans WO-1 : CAWG_02687 || 1 0.58 0.52 0.65 1.41 0.53 0.42 0.51 1.26 0.48 -0.04 0.19 0.99 -0.04 -0.09 -0.20 0.51
450 || orf19.1247 || || || Ortholog of C. dubliniensis CD36 : Cd36_45230, C. parapsilosis CDC317 : CPAR2_500450, Candida tenuis NRRL Y-1498 : CANTEDRAFT_103249 and Debaryomyces hansenii CBS767 : DEHA2C07524g || 1 0.31 0.35 0.35 0.61 0.17 0.46 0.11 0.38 0.40 0.17 0.53 0.07 -0.13 -0.13 -0.10 0.08
451 || orf19.5438 || || || Putative ubiquitin-protein ligase; role in protein sumoylation, protein ubiquitination; Spider biofilm induced || 1 0.78 0.80 0.56 0.50 0.44 0.38 0.30 0.54 0.22 -0.28 0.63 0.34 -0.00 -0.40 -0.46 0.04
452 || orf19.1940 || || || Ortholog(s) have role in cellular response to cadmium ion, detoxification of cadmium ion, ubiquinone biosynthetic process and mitochondrial inner membrane localization || 1 0.46 0.17 0.38 0.22 0.24 0.30 0.13 0.22 0.50 -0.41 0.30 0.04 -0.22 -0.07 -0.28 -0.05
453 || orf19.3715 || ASF1 || || Protein similar to S. cerevisiae Asf1p, a chromatin assembly complex component; likely to be essential for growth, based on an insertional mutagenesis strategy || 1 1.53 0.15 1.64 1.38 -0.28 0.04 0.50 0.72 0.75 0.63 1.05 -0.00 0.01 0.15 -0.10 -0.10
454 || orf19.905 || AVT7 || || Ortholog of S. cerevisiae Avt7 transporter; repressed upon adherence to polystyrene; constitutive expression independent of MTL or white-opaque status; Spider biofilm induced || 1 1.17 0.14 1.03 1.24 -0.09 0.10 0.56 0.51 0.72 0.21 0.37 -0.27 0.14 0.19 0.06 -0.32
455 || orf19.1155 || DPP2 || || Protein similar to S. cerevisiae pyrophosphate phosphatase Lpp1p; possible role in farnesol biosynthesis || 1 1.42 0.24 1.32 1.37 -0.27 0.49 0.58 0.50 0.89 -0.03 0.73 -0.04 0.22 -0.02 0.19 0.08
456 || orf19.4985 || GUP1 || || Putative O-acyltransferase with a role in glycerol uptake; functionally complements growth of S. cerevisiae gup1 mutant under salt stress; required for normal ergosterol distribution, hyphal growth, biofilm formation || 1 0.95 0.10 1.01 1.19 -0.29 -0.01 0.28 0.11 0.60 0.14 0.21 -0.30 -0.27 -0.17 0.17 -0.36
457 || orf19.2883 || CSO99 || || Protein of unknown function; Hap43-repressed gene; protein not conserved in S. cerevisiae || 1 1.38 0.35 1.24 1.41 -0.42 0.69 0.60 0.27 0.62 -0.24 0.30 0.14 0.17 -0.55 -0.23 -0.44
458 || orf19.3872 || || || Protein of unknown function; oral infection induced; mutants have reduced capacity to damage oral epithelial cells; rat catheter biofilm repressed || 1 0.45 -0.06 0.38 0.95 -0.12 0.09 0.33 0.24 0.22 0.07 0.19 0.18 0.25 -0.13 -0.13 -0.14
459 || orf19.2883 || CSO99 || || Protein of unknown function; Hap43-repressed gene; protein not conserved in S. cerevisiae || 1 1.25 0.26 0.67 1.07 0.02 0.28 -0.19 -0.25 0.76 -0.32 -0.14 0.63 -0.04 -0.52 -0.22 -0.17
460 || orf19.1144 || || || Protein with SEL-1 like protein domain; early-stage flow model biofilm induced || 1 0.71 0.06 0.44 0.61 -0.17 0.08 0.39 0.05 0.26 -0.27 -0.15 0.03 0.28 -0.12 -0.18 0.01
461 || orf19.2039 || MSF1 || || Putative phenylalanine-tRNA ligase; protein level decreases in stationary phase cultures; Hap43p-repressed gene || 1 0.95 0.22 0.64 0.48 -0.14 0.05 0.24 0.45 0.54 0.01 -0.41 0.00 0.09 -0.46 0.04 -0.45
462 || orf19.2883 || CSO99 || || Protein of unknown function; Hap43-repressed gene; protein not conserved in S. cerevisiae || 1 1.59 1.24 1.35 1.33 -0.26 0.30 0.05 0.24 0.64 -0.36 -0.65 0.39 0.58 -0.56 -0.34 -0.75
463 || orf19.191 || KIC1 || || Member of the GCK-III subfamily of eukaryotic Ste20p kinases; in RAM cell wall integrity signaling network; role in cell separation, azole sensitivity; required for hyphal growth; constitutive expression is MTL, white-opaque independent || 1 0.58 0.48 0.56 0.54 -0.09 -0.16 -0.12 0.26 0.30 -0.12 -0.06 -0.04 0.18 -0.31 -0.23 0.05
464 || orf19.723 || BCR1 || || Transcription factor; regulates a/alpha biofilm formation, matrix, cell-surface-associated genes; confers adherence, impermeability, impenetrability, fluconazole resistance; Tup1/Tec1/Mnl1-regulated; mRNA binds She3; Spider biofilm induced || 1 0.25 0.27 0.57 0.65 0.24 0.34 -0.01 -0.16 0.51 0.44 -0.40 0.02 0.60 -0.09 0.47 0.16
465 || orf19.6973 || || || ATP-dependent LON protease family member; Hap43-repressed gene; regulated by Gcn2 and Gcn4; Spider biofilm induced || 1 0.34 0.32 0.54 0.36 0.04 -0.05 0.28 -0.02 1.09 -0.09 -0.33 0.39 0.47 0.14 0.31 0.25
466 || orf19.5573 || || || Protein of unknown function; expression downregulated in an ssr1 null mutant || 1 0.21 0.39 0.81 0.91 0.26 0.13 -0.09 -0.18 1.29 0.05 -0.20 0.16 0.76 0.37 0.18
467 || orf19.2071 || || || Protein of unknown function; induced by alpha pheromone in SpiderM medium || 1 0.06 0.42 1.28 0.80 0.51 0.82 0.27 0.10 1.82 0.12 0.22 1.18 1.13 -0.41 0.72 -0.10
468 || orf19.4566 || || || Protein similar to S. cerevisiae Rot1p, which has roles in cytoskeletal dynamics and cell wall biosynthesis; predicted Kex2p substrate || 1 -0.01 0.64 0.34 0.59 0.09 0.33 0.04 0.14 0.80 0.09 0.34 0.76 0.27 0.07 0.21 0.31
469 || orf19.2001 || || || Has domain(s) with predicted L-ascorbic acid binding, iron ion binding, oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen and 2-oxoglutarate as one donor, more || 1 0.54 0.45 0.65 0.72 0.14 0.13 -0.16 0.31 0.64 0.55 0.16 0.60 -0.08 0.05 0.25 0.08
470 || orf19.3466 || || || Predicted methyltransferase; downregulated by fluphenazine treatment or in an azole-resistant strain that overexpresses CDR1 and CDR2 || 1 0.42 0.39 1.17 0.67 -0.09 0.17 -0.13 0.15 0.46 0.03 0.25 0.76 0.33 -0.23 0.31 0.28
471 || orf19.2066 || || || Ortholog(s) have cytoplasm localization || 1 0.29 0.17 1.09 0.76 0.90 0.76 0.03 0.29 0.10 0.15 0.22 0.04 1.17 -0.54 0.44 -0.25
472 || orf19.7326 || || || Ortholog(s) have protein-lysine N-methyltransferase activity, role in peptidyl-lysine dimethylation and cytoplasm, nucleus localization || 1 0.17 0.34 0.63 0.33 0.42 0.33 -0.04 0.32 0.35 -0.17 -0.14 0.09 0.67 -0.02 0.17 0.17
473 || orf19.232 || || || RNA polymerase II mediator complex subunit; possibly an essential gene, disruptants not obtained by UAU1 method || 1 0.43 0.43 0.96 0.60 0.45 0.63 -0.17 0.14 0.22 -0.06 0.38 0.38 1.33 0.38 0.66 0.26
474 || orf19.5559 || RAV2 || || Protein similar to S. cerevisiae Rav2; a regulator of (H+)-ATPase in vacuolar membrane; transposon mutation affects filamentous growth || 1 0.23 0.33 0.95 0.49 0.35 0.46 -0.05 0.23 0.26 0.04 0.44 0.34 1.45 0.21 0.09 -0.32
475 || orf19.6309 || MSS11 || || Transcription factor; activator that binds to Flo8 via a LisH motif to cooperatively activate transcription of hypha-specific genes; required for hyphal growth || 1 0.32 0.39 0.76 0.35 0.19 -0.00 0.20 0.16 0.18 0.04 -0.13 0.10 1.09 0.36 0.30 -0.03
476 || orf19.2799 || GPI8 || || Protein similar to S. cerevisiae Gpi8p, which is a subunit of the GPI transamidase complex that adds GPI anchors to proteins; likely to be essential for growth, based on an insertional mutagenesis strategy || 1 0.07 0.39 1.00 0.58 0.13 -0.39 0.10 0.14 0.22 0.23 -0.06 -0.02 0.51 0.40 -0.17 0.17
477 || orf19.5384 || CHS8 || || Chitin synthase required for synthesis of long-chitin fibrils; nonessential; 8 or 9 membrane spanning regions; mRNA present in yeast and hyphae; induced during cell wall regeneration; flow model biofilm repressed || 1 0.53 0.86 0.90 0.83 0.57 -0.70 0.10 0.28 0.34 0.14 -0.09 -0.02 0.97 0.39 -0.20 0.25
478 || orf19.4308 || HSL1 || || Probable protein kinase involved in determination of morphology during the cell cycle of both yeast-form and hyphal cells via regulation of Swe1p and Cdc28p; required for full virulence and kidney colonization in mouse systemic infection || 1 0.54 1.05 1.03 0.73 0.97 -0.23 0.60 0.80 1.39 0.59 0.37 0.13 1.41 0.49 -0.20 0.27
479 || orf19.2546 || TRP2 || || Putative anthranilate synthase with a predicted role in tryptophan biosynthesis; regulated by Gcn2p and Gcn4p || 1 0.27 0.68 0.64 0.65 0.61 -0.17 0.34 0.22 1.00 0.08 0.18 0.24 0.74 0.04 -0.24 -0.17
480 || orf19.270 || || || Ortholog of C. parapsilosis CDC317 : CPAR2_102150, C. dubliniensis CD36 : Cd36_82780, Pichia stipitis Pignal : psti_CGOB_00155 and Candida orthopsilosis Co 90-125 : CORT_0B03450 || 1 0.45 0.62 0.60 0.44 0.47 -0.13 0.42 0.19 0.73 -0.18 0.04 0.07 0.60 -0.08 0.05 -0.03
481 || orf19.3430 || || || Plasma membrane-associated protein; physically interacts with TAP-tagged Nop1p || 1 0.62 0.83 1.00 0.92 0.53 -0.21 0.07 0.02 0.32 -0.00 0.16 0.34 1.00 -0.16 -0.17 0.42
482 || orf19.2007 || || || Ortholog(s) have role in Golgi to vacuole transport, ascospore wall assembly, retrograde transport, endosome to Golgi and GARP complex, mitochondrion localization || 1 1.01 0.88 1.09 0.81 0.94 0.17 0.01 0.20 1.17 -0.17 0.31 -0.19 1.37 0.03 -0.08 0.67
483 || orf19.7305 || || || Ortholog of C. dubliniensis CD36 : Cd36_34510, Candida tropicalis MYA-3404 : CTRG_05938 and Candida albicans WO-1 : CAWG_02183 || 1 0.45 0.57 1.14 0.59 0.28 0.10 -0.04 0.16 0.68 -0.08 0.00 -0.13 0.59 0.20 -0.03 0.42
484 || orf19.3156 || || || Protein of unknown function; induced by Mnl1 under weak acid stress || 1 0.74 0.88 0.98 0.45 0.07 0.86 -0.01 0.03 0.50 0.13 0.31 -0.19 0.26 -0.02 -0.04 -0.18
485 || orf19.3370 || DOT4 || || Protein similar to ubiquitin C-terminal hydrolase; localizes to cell surface of hyphal cells, but not yeast-form cells; repressed upon high-level peroxide; Hap43p-induced; rat catheter biofilm induced || 1 0.61 1.00 1.11 1.09 0.45 0.60 0.53 0.36 0.01 0.39 0.46 -0.03 0.63 -0.02 0.13 -0.50
486 || orf19.5337 || UBC15 || || Putative E2 ubiquitin-conjugating enzyme || 1 0.94 0.90 0.76 1.01 0.34 -0.12 0.12 0.30 -0.08 0.20 -0.00 -0.50 -0.15 -0.25 0.16 0.01
487 || orf19.4306 || || || Ortholog(s) have methylthioribulose 1-phosphate dehydratase activity, role in L-methionine salvage from methylthioadenosine and cytoplasm localization || 1 1.50 1.55 1.17 1.69 0.07 0.34 -0.11 0.40 -0.11 0.18 0.23 -0.18 -0.17 -0.40 -0.28 -0.30
488 || orf19.6731 || || || Protein of unknown function; repressed by alpha pheromone in SpiderM medium; Spider biofilm induced || 1 2.44 2.34 2.12 2.63 0.88 0.88 0.89 0.85 -0.06 0.68 -0.21 -0.31 -0.04 -0.29 -0.23 -0.51
489 || orf19.6731 || || || Protein of unknown function; repressed by alpha pheromone in SpiderM medium; Spider biofilm induced || 1 2.58 2.78 2.04 2.67 1.26 0.90 0.75 0.54 -0.01 0.54 0.10 -0.39 -0.06 -0.41 0.18 -0.70
490 || orf19.6731 || || || Protein of unknown function; repressed by alpha pheromone in SpiderM medium; Spider biofilm induced || 1 1.99 2.45 2.04 2.84 0.98 0.98 0.69 0.57 0.22 0.75 0.33 -0.26 -0.13 -0.31 0.14 -0.11
491 || orf19.6731 || || || Protein of unknown function; repressed by alpha pheromone in SpiderM medium; Spider biofilm induced || 1 2.12 2.21 2.33 2.94 0.69 1.29 0.15 0.42 0.13 0.72 0.23 -0.02 -0.22 -0.06 0.09 -0.18
492 || orf19.6731 || || || Protein of unknown function; repressed by alpha pheromone in SpiderM medium; Spider biofilm induced || 1 1.71 1.75 2.16 2.30 0.56 0.82 0.41 0.25 0.20 0.49 -0.06 -0.38 -0.33 -0.10 -0.28 -0.19
493 || orf19.4306 || || || Ortholog(s) have methylthioribulose 1-phosphate dehydratase activity, role in L-methionine salvage from methylthioadenosine and cytoplasm localization || 1 1.08 1.07 1.17 1.18 0.34 0.19 -0.21 0.20 0.28 0.26 0.04 0.04 0.19 0.24 -0.07 -0.45
494 || orf19.192 || || || Ortholog of C. dubliniensis CD36 : Cd36_19320, C. parapsilosis CDC317 : CPAR2_209670, Candida tenuis NRRL Y-1498 : CANTEDRAFT_113478 and Debaryomyces hansenii CBS767 : DEHA2C15136g || 1 1.39 1.02 1.36 1.44 0.61 0.06 0.06 0.10 0.36 0.31 0.27 -0.44 0.22 0.47 0.23 0.02
495 || orf19.7501 || || || Nucleosome assembly protein; protein present in exponential and stationary growth phase yeast cultures || 1 1.07 1.11 0.98 1.23 1.02 0.61 0.64 0.77 0.09 0.26 0.61 -0.06 0.31 0.04 0.37 -0.13
496 || orf19.6639 || || || Ortholog of S. cerevisiae Mdm36; mitochondrial distribution and morphology protein; Hap43-repressed gene || 1 1.61 1.57 1.41 1.00 1.15 0.85 0.23 0.13 0.08 0.21 0.07 -0.23 0.21 0.05 0.50 -0.14
497 || orf19.6639 || || || Ortholog of S. cerevisiae Mdm36; mitochondrial distribution and morphology protein; Hap43-repressed gene || 1 1.18 1.29 1.15 0.95 0.96 0.71 0.06 0.19 -0.03 0.05 0.29 -0.02 0.54 0.05 0.28 -0.03
498 || orf19.1527 || || || Protein of unknown function; Spider biofilm induced || 1 1.23 1.40 1.41 1.52 1.22 1.23 0.21 -0.00 -0.21 -0.28 0.79 -0.10 0.11 -0.23 0.46 -0.44
499 || orf19.1161 || PLD1 || || Phospholipase D1; required for phosphatidic acid and for most diacylglycerol production; required for wild-type mouse virulence, but not rat oral virulence; mutant defect in hyphal growth on solid substrates; similar to S. cerevisiae Spo14p || 1 0.90 1.01 0.57 0.59 0.59 0.47 -0.12 -0.02 0.00 0.05 0.02 -0.38 -0.20 -0.06 0.16 -0.10
500 || orf19.1161 || PLD1 || || Phospholipase D1; required for phosphatidic acid and for most diacylglycerol production; required for wild-type mouse virulence, but not rat oral virulence; mutant defect in hyphal growth on solid substrates; similar to S. cerevisiae Spo14p || 1 1.09 1.07 0.71 0.78 0.35 0.33 -0.20 -0.03 -0.29 0.03 -0.32 -0.50 -0.39 -0.06 -0.06 -0.30
501 || orf19.4522 || || || Ortholog(s) have role in response to drug and cytosol, nucleus localization || 1 1.41 1.56 1.16 1.05 0.38 0.75 0.36 0.00 0.33 0.25 -0.50 -0.63 -0.07 0.02 -0.02 -0.53
502 || orf19.4522 || || || Ortholog(s) have role in response to drug and cytosol, nucleus localization || 1 0.92 0.90 0.98 0.88 0.09 0.67 -0.08 -0.23 0.17 0.05 -0.57 -0.55 0.03 0.14 -0.23 -0.31
503 || orf19.5220 || || || Putative RNA exonuclease; induced in a ssr1 null mutant || 1 1.22 1.04 1.03 1.14 0.72 0.65 0.27 -0.01 -0.36 0.57 -0.45 -0.55 0.59 -0.03 0.11 -0.31
504 || orf19.1542 || HEX3 || || Protein similar to S. cerevisiae Hex3p, which is involved in DNA damage response; transposon mutation affects filamentous growth || 1 0.98 0.86 0.61 0.79 0.51 0.43 -0.22 -0.22 0.21 -0.24 0.00 0.09 0.22 -0.17 0.01 -0.21
505 || orf19.6416 || || || Protein involved in N-glycosylation; Spider biofilm induced; rat catheter biofilm repressed || 1 1.37 0.55 0.93 1.85 0.29 1.06 1.10 -0.26 1.04 -0.09 -0.67 0.46 -0.05 0.15 -0.22
506 || orf19.1026 || || || Ortholog(s) have role in exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA and LSU-rRNA), more || 1 1.08 0.22 0.73 0.76 0.37 1.08 0.45 0.15 0.40 0.38 -0.20 -0.17 0.26 0.06 0.23 -0.72
507 || orf19.1902 || NOC4 || || Putative nucleolar protein; Hap43-induced; mutation confers resistance to 5-fluorocytosine (5-FC), 5-fluorouracil (5-FU), and tubercidin (7-deazaadenosine); Spider biofilm induced || 1 1.29 0.58 0.89 1.22 0.59 1.28 -0.07 0.14 1.01 0.89 -0.12 -0.58 0.16 -0.04 -0.12 -0.43
508 || orf19.4793 || || || Putative ribosome-associated protein; ortholog of S. cerevisiae Tma16; Hap43-induced gene; Spider biofilm induced || 1 2.08 1.32 0.94 1.47 0.95 1.52 0.58 0.17 1.77 1.39 0.01 0.79 0.28 -0.21 -0.43
509 || orf19.1673 || PPT1 || || Putative serine/threonine phosphatase; induced in high iron || 1 0.90 0.34 0.63 0.96 0.04 0.42 0.43 0.33 0.77 1.01 -0.10 0.25 0.57 0.15 -0.03 -0.62
510 || orf19.1177 || || || Ortholog of S. cerevisiae Rtt106; histone chaperone that regulates chromatin structure in transcribed and silenced chromosomal regions; affects transcriptional elongation; Hap43-repressed; Spider biofilm repressed || 1 0.79 -0.07 0.69 0.84 -0.21 0.03 0.23 0.44 0.92 0.32 -0.15 0.14 -0.14 0.13 -0.16 -0.25
511 || orf19.1728 || || || Ortholog of C. dubliniensis CD36 : Cd36_81190, C. parapsilosis CDC317 : CPAR2_503840, Debaryomyces hansenii CBS767 : DEHA2A09042g and Pichia stipitis Pignal : PICST_42519 || 1 0.88 -0.03 1.07 1.30 -0.00 0.70 -0.03 -0.06 1.60 -0.24 -0.53 -0.10 -0.08 -0.29 -0.21 -0.60
512 || orf19.417 || MTM1 || || Ortholog(s) have metallochaperone activity, role in manganese ion transport and mitochondrion localization || 1 1.15 0.16 0.96 1.52 0.09 0.83 0.09 0.64 1.42 0.25 -0.52 0.17 0.35 -0.06 -0.42 -0.39
513 || orf19.4095 || || || Ortholog of C. parapsilosis CDC317 : CPAR2_407020, C. dubliniensis CD36 : Cd36_23460, Debaryomyces hansenii CBS767 : DEHA2B02002g and Pichia stipitis Pignal : PICST_31649 || 1 0.91 0.27 1.18 1.64 0.15 1.24 -0.20 0.39 2.48 0.49 -0.23 -0.01 0.26 0.73 0.21 -0.16
514 || orf19.5954 || || || Ortholog(s) have enzyme activator activity, role in ascospore wall assembly, meiosis I, positive regulation of protein catabolic process and anaphase-promoting complex localization || 1 1.09 -0.06 0.94 0.66 0.26 0.81 -0.19 0.13 0.88 -0.09 -0.15 -0.14 -0.07 0.10 -0.17 0.27
515 || orf19.1122 || || || Protein of unknown function; induced by alpha pheromone in SpiderM medium; Spider biofilm induced || 1 0.86 0.01 0.60 1.22 0.02 0.56 -0.37 -0.09 0.66 -0.21 -0.38 0.01 -0.23 0.12 -0.20 0.35
516 || orf19.5520 || ASG7 || || a-cell specific protein of unknown function; two predicted transmembrane domains; member of conserved Mcm1 regulon; induced by alpha pheromone in SpiderM medium || 1 1.22 0.64 0.59 1.40 -0.15 0.29 0.53 -0.42 1.18 0.31 -0.54 -0.10 0.52 0.08 0.30
517 || orf19.3680 || SEP7 || || Septin, required for wild-type invasive growth in vitro but not required for virulence in a mouse model of systemic infection; localizes to hyphal septum or bud neck; Asn-rich; aberrant gel mobility; phosphorylated in vitro by Gin4p || 1 1.61 0.84 0.59 1.24 0.36 0.29 0.09 -0.02 1.26 0.81 0.04 0.41 0.36 0.49 -0.18 0.24
518 || orf19.6698 || || || Ortholog(s) have asparagine-tRNA ligase activity, role in mitochondrial asparaginyl-tRNA aminoacylation and mitochondrion localization || 1 1.68 0.71 0.32 1.66 0.39 0.81 0.29 0.31 2.00 0.43 0.00 0.43 0.20 0.31 0.29 0.30
519 || orf19.5492 || || || Ortholog(s) have mRNA binding, pre-mRNA 5'-splice site binding activity, role in mRNA 5'-splice site recognition and U1 snRNP, U2-type prespliceosome, commitment complex localization || 1 0.50 0.09 0.38 0.44 -0.14 0.28 0.12 0.12 0.39 0.13 -0.05 0.04 0.23 0.09 -0.15 0.31
520 || orf19.1050 || || || Ortholog of S. cerevisiae : YMR087W, C. glabrata CBS138 : CAGL0J01397g, C. dubliniensis CD36 : Cd36_03920, C. parapsilosis CDC317 : CPAR2_107150 and Pichia stipitis Pignal : PICST_61741 || 1 0.45 0.43 0.96 0.75 0.95 1.07 -0.03 0.09 1.03 0.43 0.07 0.12 0.16 0.48 0.01 0.34
521 || orf19.5524 || || || Ortholog of C. dubliniensis CD36 : Cd36_62790, C. parapsilosis CDC317 : CPAR2_601680, Candida tenuis NRRL Y-1498 : cten_CGOB_00252 and Debaryomyces hansenii CBS767 : DEHA2A06622g || 1 0.17 0.28 1.16 1.04 0.98 1.06 0.25 0.80 0.83 -0.33 0.69 -0.06 0.56 0.03 0.32 0.18
522 || orf19.3209 || FGR42 || || Protein lacking an ortholog in S. cerevisiae; transposon mutation affects filamentous growth || 1 0.54 0.06 1.83 1.71 0.71 1.96 0.57 1.50 0.54 -0.10 1.02 -0.30 1.52 -0.98 1.10 0.34
523 || orf19.7449 || || || Ortholog(s) have role in mitochondrial genome maintenance, plasmid maintenance and cytosol, mitochondrion localization || 1 0.45 0.28 1.22 1.12 0.39 0.89 0.33 1.13 0.84 -0.12 0.41 -0.42 1.56 -0.03 0.39 0.06
524 || orf19.3907 || || || Ortholog of Candida albicans WO-1 : CAWG_04797 || 1 1.11 0.91 1.12 1.19 0.59 0.82 0.22 1.17 -0.07 -0.03 0.90 -0.22 0.83 -0.29 1.00 0.38
525 || orf19.6667 || || || Predicted histone deacetylase activity; Spider biofilm induced || 1 0.61 0.62 0.94 0.88 0.40 0.58 0.01 0.27 0.02 -0.13 0.74 -0.22 0.64 -0.22 0.52 0.49
526 || orf19.7282 || PEX13 || || Protein required for peroxisomal protein import mediated by PTS1 and PTS2 targeting sequences; transcript induced in an RHE model of oral candidiasis; Hap43-repressed gene || 1 0.37 0.27 0.93 0.87 0.04 0.32 -0.36 -0.14 0.04 0.13 -0.33 -0.06 0.30 -0.40 0.29 -0.12
527 || orf19.7666 || || || Predicted membrane transporter, member of the anion:cation symporter (ACS) family, major facilitator superfamily (MFS) || 1 0.12 0.62 1.44 0.98 0.54 0.59 -0.21 0.07 0.33 -0.19 -0.36 -0.26 0.97 -0.07 0.59 -0.86
528 || orf19.3427 || || || Ortholog of Candida albicans WO-1 : CAWG_05207 || 1 0.60 0.54 1.05 1.14 0.20 0.16 0.02 0.09 0.35 -0.41 -0.16 -0.17 0.53 -0.27 0.57 -0.23
529 || orf19.3427 || || || Ortholog of Candida albicans WO-1 : CAWG_05207 || 1 0.46 0.51 1.27 1.01 0.17 0.15 0.03 -0.06 0.42 -0.58 -0.15 -0.42 0.52 -0.36 0.45 -0.53
530 || orf19.296 || || || Ortholog of C. dubliniensis CD36 : Cd36_82980, C. parapsilosis CDC317 : CPAR2_102360, Candida tenuis NRRL Y-1498 : cten_CGOB_00165 and Debaryomyces hansenii CBS767 : DEHA2G00990g || 1 0.52 0.63 0.96 0.92 0.42 0.53 -0.09 -0.16 0.44 -0.43 -0.41 -0.45 0.58 -0.46 0.27 -0.58
531 || orf19.296 || || || Ortholog of C. dubliniensis CD36 : Cd36_82980, C. parapsilosis CDC317 : CPAR2_102360, Candida tenuis NRRL Y-1498 : cten_CGOB_00165 and Debaryomyces hansenii CBS767 : DEHA2G00990g || 1 0.50 0.60 1.21 0.92 0.41 0.44 -0.15 -0.15 0.33 -0.51 -0.47 -0.55 0.62 -0.45 0.28 -0.55
532 || orf19.296 || || || Ortholog of C. dubliniensis CD36 : Cd36_82980, C. parapsilosis CDC317 : CPAR2_102360, Candida tenuis NRRL Y-1498 : cten_CGOB_00165 and Debaryomyces hansenii CBS767 : DEHA2G00990g || 1 0.47 0.52 1.09 0.74 0.47 0.55 -0.16 -0.13 0.50 -0.29 -0.39 -0.59 0.68 -0.37 0.38 -0.44
533 || orf19.2809 || CTN3 || || Peroxisomal carnitine acetyl transferase; no obvious metabolic, hyphal, virulence defects in Ura+ strain; induced by macrophage engulfment, hyphal growth, starvation, nonfermentable carbon sources; rat catheter, Spider biofilm induced || 1 0.46 0.56 1.05 0.86 0.57 0.20 -0.03 -0.08 0.10 -0.19 -0.34 -0.22 0.59 -0.25 0.33 -0.13
534 || orf19.2181 || || || Ortholog of Spathaspora passalidarum NRRL Y-27907 : spas_CGOB_00067 and Candida albicans WO-1 : CAWG_05895 || 1 0.31 0.51 1.00 1.03 0.44 0.31 -0.01 -0.13 0.37 -0.16 -0.17 -0.30 0.70 -0.50 0.23 -0.27
535 || orf19.296 || || || Ortholog of C. dubliniensis CD36 : Cd36_82980, C. parapsilosis CDC317 : CPAR2_102360, Candida tenuis NRRL Y-1498 : cten_CGOB_00165 and Debaryomyces hansenii CBS767 : DEHA2G00990g || 1 0.47 0.57 0.82 0.79 0.31 0.22 -0.10 -0.13 -0.03 -0.16 -0.15 -0.32 0.58 -0.61 0.41 -0.24
536 || orf19.296 || || || Ortholog of C. dubliniensis CD36 : Cd36_82980, C. parapsilosis CDC317 : CPAR2_102360, Candida tenuis NRRL Y-1498 : cten_CGOB_00165 and Debaryomyces hansenii CBS767 : DEHA2G00990g || 1 0.46 0.53 0.61 0.90 0.30 0.36 -0.13 -0.19 0.05 -0.05 -0.32 -0.06 0.42 -0.40 0.44 -0.30
537 || orf19.280 || || || Ortholog of C. dubliniensis CD36 : Cd36_82875 and Candida albicans WO-1 : CAWG_02609 || 1 0.61 0.58 0.52 1.01 0.40 0.47 -0.12 -0.09 0.44 -0.23 -0.39 -0.38 0.55 -0.52 0.41 -0.43
538 || orf19.1655.3 || || || Ortholog(s) have role in cation transport, regulation of membrane potential and plasma membrane localization || 1 1.28 1.31 1.62 2.08 0.88 0.91 0.18 0.40 -0.16 -0.32 -0.24 -0.62 1.50 -0.16 0.87 -0.33
539 || orf19.1655.3 || || || Ortholog(s) have role in cation transport, regulation of membrane potential and plasma membrane localization || 1 1.38 1.31 1.80 2.14 0.90 0.95 0.15 0.24 -0.31 -0.38 -0.30 -0.47 1.45 0.13 1.06 -0.37
540 || orf19.1655.3 || || || Ortholog(s) have role in cation transport, regulation of membrane potential and plasma membrane localization || 1 1.32 1.18 1.81 2.02 0.90 0.84 0.19 0.28 -0.25 -0.48 -0.36 -0.46 1.33 -0.08 0.87 0.02
541 || orf19.1655.3 || || || Ortholog(s) have role in cation transport, regulation of membrane potential and plasma membrane localization || 1 1.34 1.21 1.84 2.09 0.78 0.91 0.10 0.21 -0.23 -0.31 -0.33 -0.44 1.38 -0.06 0.86 -0.08
542 || orf19.1655.3 || || || Ortholog(s) have role in cation transport, regulation of membrane potential and plasma membrane localization || 1 1.27 1.22 1.69 2.10 0.77 0.93 0.14 0.23 -0.30 -0.44 -0.35 -0.30 1.25 -0.24 0.86 -0.12
543 || orf19.6650 || || || Ortholog of C. dubliniensis CD36 : Cd36_30990, C. parapsilosis CDC317 : CPAR2_204660, Candida tenuis NRRL Y-1498 : CANTEDRAFT_104939 and Debaryomyces hansenii CBS767 : DEHA2G23760g || 1 0.72 0.70 1.21 1.38 0.26 0.18 -0.14 0.13 -0.17 0.11 0.13 0.11 0.43 0.09 0.04 -0.20
544 || orf19.4754 || ZWF1 || || Glucose-6-phosphate dehydrogenase; antigenic in mice; activity induced by O2 or oxidizing agents H2O2, menadione, macrophage; caspofungin repressed; induced in core stress response; regulated by Gcn2, Gcn4; rat catheter biofilm repressed || 1 0.68 0.75 1.11 1.58 0.07 0.10 0.10 0.23 0.00 -0.47 0.14 0.23 0.50 -0.18 0.18 -0.11
545 || orf19.2878 || PGA15 || || Putative GPI-anchored protein || 1 0.41 0.53 0.77 0.99 -0.08 0.17 0.28 0.48 0.12 0.21 -0.00 0.12 0.34 0.08 0.46 -0.12
546 || orf19.3964 || ASH2 || || Ortholog(s) have histone methyltransferase activity (H3-K4 specific) activity || 1 0.30 0.24 0.51 0.87 0.13 -0.06 0.10 0.25 0.08 -0.15 -0.35 0.00 0.44 -0.05 0.14 0.07
547 || orf19.273 || || || Ortholog(s) have unfolded protein binding activity, role in sterol biosynthetic process and endoplasmic reticulum localization || 1 0.56 1.43 0.71 1.53 0.87 0.27 0.05 0.02 0.71 0.25 0.00 0.17 0.89 -0.20 0.35 -0.02
548 || orf19.2590 || || || Putative dethiobiotin synthetase; transcript upregulated in clinical isolates from HIV+ patients with oral candidiasis; Hap43-repressed; GlcNAc-induced protein; Spider biofilm induced || 1 1.92 1.56 2.28 2.27 -0.41 1.02 0.16 0.07 1.39 -0.29 -0.39 0.15 1.59 0.77 0.81 -0.36
549 || orf19.4511 || || || Ortholog of Candida albicans WO-1 : CAWG_04197 || 1 0.53 0.32 0.94 0.88 0.05 0.63 -0.01 -0.29 0.91 -0.14 -0.22 -0.01 0.98 -0.28 -0.34
550 || orf19.6997 || ATO5 || || Putative fungal-specific transmembrane protein || 1 0.53 0.38 1.24 1.01 0.31 1.22 0.31 0.01 0.72 -0.01 0.20 0.07 1.65 0.28 -0.19
551 || orf19.4404 || PGA49 || || Putative GPI-anchored protein || 1 -0.12 0.24 1.69 1.25 0.76 1.68 0.05 0.25 0.88 -0.31 0.26 0.11 2.04 -0.46 -0.21 -0.10
552 || orf19.3112 || ZRT1 || || Putative zinc transporter; acts with Pra1 in sequestration of zinc from host tissues during infection; hyphal, macrophage-induced; alkaline induced upon adherence to polystyrene; induced in oralpharyngeal candidasis; Spider biofilm induced || 1 0.21 0.34 1.35 0.74 0.32 0.52 -0.14 0.02 0.43 -0.23 0.14 0.14 0.90 -0.24 -0.14 -0.48
553 || orf19.1582 || || || Predicted membrane transporter; member of the drug:proton antiporter (12 spanner) (DHA1) family, major facilitator superfamily (MFS); mRNA binds She3 || 1 0.35 0.42 1.60 1.52 0.60 0.57 0.12 -0.05 0.58 -0.42 -0.13 -0.14 1.58 -0.22 -0.09 -0.48
554 || orf19.7013 || || || Ortholog of C. dubliniensis CD36 : Cd36_70940, C. parapsilosis CDC317 : CPAR2_300280, Debaryomyces hansenii CBS767 : DEHA2F22220g and Pichia stipitis Pignal : PICST_32459 || 1 0.07 0.54 1.08 0.87 0.59 0.33 -0.07 0.07 0.59 -0.47 -0.22 -0.00 0.81 -0.03 -0.08 -0.10
555 || orf19.7157 || || || Protein with a tubulin binding cofactor C domain; flow model biofilm induced || 1 0.21 0.23 0.64 1.24 0.68 0.35 0.42 0.25 0.41 -0.06 -0.14 -0.06 0.27 0.16 -0.08 -0.02
556 || orf19.4520 || || || Putative gluconokinase; rat catheter biofilm induced || 1 0.25 0.22 1.07 1.49 0.29 0.41 0.54 0.38 0.27 0.06 -0.06 -0.36 0.50 0.41 -0.11 0.35
557 || orf19.5553 || || || Ortholog(s) have methionine-R-sulfoxide reductase activity, role in cellular response to oxidative stress and cytoplasm, nucleus localization || 1 0.54 -0.07 1.16 1.09 0.34 0.41 0.58 0.74 0.25 -0.15 0.09 -0.27 0.35 0.29 -0.04 -0.20
558 || orf19.876 || PGA33 || || Putative GPI-anchored protein of unknown function; Spider biofilm repressed || 1 0.57 0.42 1.05 0.94 0.45 -0.04 0.44 0.36 0.16 -0.26 0.02 0.20 0.45 -0.04 0.35 -0.16
559 || orf19.7556 || || || Ortholog of C. dubliniensis CD36 : Cd36_34965, C. parapsilosis CDC317 : CPAR2_200910, Candida tenuis NRRL Y-1498 : CANTEDRAFT_95984 and Debaryomyces hansenii CBS767 : DEHA2E02926g || 1 0.38 0.35 1.05 0.93 0.21 0.06 0.43 0.06 0.34 -0.12 -0.02 0.02 0.49 0.03 0.29 -0.37
560 || orf19.5110 || OPY2 || || Predicted transmembrane protein; role in cell wall biogenesis; required for Cek1 phosphorylation; Spider biofilm induced || 1 0.39 0.37 0.85 1.19 0.71 -0.09 0.68 0.31 0.55 0.43 -0.12 -0.19 0.48 0.54 0.49 -0.51
561 || orf19.6480 || || || Ortholog(s) have role in UDP-glucose transport and COPI-coated vesicle, Golgi apparatus localization || 1 0.40 0.64 0.94 1.03 0.40 -0.13 0.29 0.26 0.52 0.17 0.02 -0.15 0.79 0.36 0.22 -0.48
562 || orf19.1949 || VPS1 || || Dynamin-family GTPase-related protein; induced upon adherence to polystyrene; regulated by Gcn2p and Gcn4p || 1 0.50 0.44 1.03 0.86 0.71 -0.15 0.40 0.49 0.34 0.18 0.02 -0.23 0.42 0.20 0.09 -0.37
563 || orf19.3239 || CTF18 || || Protein with a predicted role in sister chromatid cohesion; cell-cycle regulated periodic mRNA expression || 1 0.37 0.18 0.64 0.70 0.20 0.04 0.26 0.40 0.41 0.41 0.07 -0.20 0.21 0.11 0.19 -0.22
564 || orf19.7457 || || || Protein with Mob2p-dependent hyphal regulation || 1 0.11 0.31 0.68 0.39 0.31 0.21 0.07 -0.22 0.22 0.14 -0.09 -0.16 0.44 0.45 0.26 -0.11
565 || orf19.5501 || YAF9 || || Subunit of the NuA4 histone acetyltransferase complex; transcript regulated by Mig1; possibly an essential gene, disruptants not obtained by UAU1 method || 1 0.10 0.18 0.94 0.69 0.38 0.17 0.09 0.08 0.26 0.15 -0.32 -0.28 0.49 0.33 0.00 -0.43
566 || orf19.5952 || || || Protein of unknown function; induced by nitric oxide independent of Yhb1; Sef1, Sfu1, and Hap43-induced; rat catheter and Spider biofilm induced || 1 0.60 0.43 1.39 1.29 0.65 0.23 0.14 0.27 0.18 -0.51 -0.34 -0.66 1.25 0.76 0.12 -0.31
567 || orf19.6399 || ATS1 || || Protein required for modification of wobble nucleosides in tRNA; induced upon adherence to polystyrene; regulated by Sef1, Sfu1, and Hap43 || 1 0.31 0.42 0.52 0.41 0.16 0.24 -0.03 0.03 0.15 -0.13 -0.17 -0.17 0.82 0.37 -0.11 -0.03
568 || orf19.2154 || HXK1 || || N-acetylglucosamine (GlcNAc) kinase; involved in GlcNAc utilization; required for wild-type hyphal growth and mouse virulence; GlcNAc-induced transcript; induced by alpha pheromone in SpiderM medium || 1 0.84 0.91 0.92 0.79 0.23 0.21 0.29 0.48 0.71 0.16 -0.39 -0.80 1.03 0.88 0.02 -0.29
569 || orf19.2346 || || || Putative protein of unknown function, transcription is positively regulated by Tbf1p || 1 0.63 0.66 0.74 0.67 0.47 0.21 0.23 0.11 0.32 -0.00 -0.35 -0.27 0.28 0.42 0.16 -0.14
570 || orf19.4743 || AFG1 || || Putative mitochondrial ATPase of the AAA family; similar but not orthologous to S. cerevisiae Afg1; mutant is viable; regulated by Sef1, Sfu1, and Hap43 || 1 0.29 1.34 1.25 1.29 1.31 0.41 0.18 0.46 0.65 -0.08 -0.20 -0.35 0.70 0.61 0.08 -0.45
571 || orf19.6142 || || || Ortholog(s) have double-stranded DNA binding activity, role in reciprocal meiotic recombination and condensed nuclear chromosome localization || 1 0.29 0.76 0.67 1.20 1.17 0.59 0.03 -0.05 0.33 0.42 -0.29 -0.29 1.00 0.81 -0.03
572 || orf19.4294 || || || Ortholog(s) have oxidoreductase activity, role in cytochrome c-heme linkage, mitochondrial membrane organization and extrinsic to mitochondrial inner membrane localization || 1 0.95 0.77 0.66 1.03 0.83 0.62 -0.28 -0.34 0.78 -0.47 0.79 -0.14 1.15 -0.35 -0.28 0.53
573 || orf19.3995 || RIM13 || || Protease of the pH response pathway; likely to mediate activation of Rim101 via C-terminal cleavage; required for alkaline pH-induced hyphal growth and for normal chlamydospore formation; Hap43-repressed; flow model biofilm induced || 1 0.45 0.42 0.47 0.35 0.45 0.22 -0.16 -0.05 0.29 -0.57 0.09 0.02 0.44 -0.16 -0.01 0.43
574 || orf19.360 || FUR4 || || Putative uracil permease || 1 0.26 0.48 1.12 0.75 0.72 1.02 -0.43 -0.40 0.56 -0.96 0.08 -0.12 0.41 -0.56 -0.08 0.59
575 || orf19.5965 || || || Ortholog(s) have ubiquitin-ubiquitin ligase activity, role in ER-associated ubiquitin-dependent protein catabolic process, protein ubiquitination, response to stress and cytoplasm, nucleus localization || 1 0.37 0.26 0.55 0.29 0.36 0.41 -0.19 -0.20 0.73 -0.28 0.10 -0.01 0.20 -0.03 0.03 0.55
576 || orf19.2991 || HOL1 || || Putative MFS transporter; regulated by Nrg1; macrophage/pseudohyphal-repressed; induced by alpha pheromone in SpiderM medium; possibly an essential gene, disruptants not obtained by UAU1 method || 1 0.65 0.93 2.23 0.98 0.81 1.56 -0.42 -0.45 1.38 -0.30 0.03 -0.36 0.91 -0.29 0.14 0.94
577 || orf19.5604 || MDR1 || || Plasma membrane MDR/MFS multidrug efflux pump; methotrexate is preferred substrate; overexpression in drug-resistant clinical isolates confers fluconazole resistance; repressed in young biofilms; rat catheter biofilm induced || 1 0.93 0.93 1.33 1.40 1.36 1.63 -0.37 -0.33 1.08 -0.46 -0.19 -0.30 0.81 -0.51 -0.16 0.85
578 || orf19.7661 || HMI1 || || ATP-dependent 3' - 5' helicase involved in maintenance of mitochondrial DNA; ortholog of S. cerevisiae Hmi1; rat catheter biofilm repressed || 1 0.77 0.56 1.38 1.20 0.66 1.02 -0.51 -0.36 0.85 -0.45 -0.32 -0.55 0.37 -0.34 -0.21 0.86
579 || orf19.6557 || || || Protein with a predicted fatty acid amide hydrolase I domain; induced by Mnl1 under weak acid stress || 1 0.48 0.34 1.15 1.16 0.49 0.56 -0.45 -0.32 0.76 -0.27 -0.16 -0.12 0.48 -0.44 -0.15 0.57
580 || orf19.2742 || || || Ortholog of C. parapsilosis CDC317 : CPAR2_400095, C. dubliniensis CD36 : Cd36_42560, Candida tenuis NRRL Y-1498 : CANTEDRAFT_113280 and Lodderomyces elongisporus NRLL YB-4239 : LELG_04166 || 1 0.52 0.39 0.73 0.84 0.64 0.79 -0.35 -0.29 0.77 -0.23 -0.25 -0.36 0.34 0.20 -0.33 0.80
581 || orf19.2494 || || || Ortholog(s) have glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity, role in glutaminyl-tRNAGln biosynthesis via transamidation, mitochondrial translation and glutamyl-tRNA(Gln) amidotransferase complex, mitochondrion localization || 1 0.71 0.31 1.00 0.67 0.58 0.34 -0.17 -0.01 0.79 -0.43 -0.11 -0.36 0.43 0.09 -0.28 0.38
582 || orf19.2351 || NIT3 || || Putative nitrilase; regulated by Gcn2p and Gcn4p; protein present in exponential and stationary growth phase yeast cultures || 1 0.55 0.37 1.29 1.08 0.41 0.28 -0.17 -0.02 0.94 -0.69 0.01 0.02 0.83 -0.46 -0.03 0.24
583 || orf19.2725 || || || Ortholog of Candida albicans WO-1 : CAWG_03525 || 1 0.54 0.51 1.27 0.98 0.34 0.71 -0.12 0.31 0.77 -0.45 -0.17 -0.13 0.53 -0.83 0.04 0.24
584 || orf19.4942 || || || Ortholog of Candida albicans WO-1 : CAWG_00134 || 1 0.58 0.40 0.80 1.08 0.87 0.59 -0.39 0.08 0.55 -0.47 0.09 0.10 0.38 -0.63 -0.23 0.23
585 || orf19.4747 || HEM14 || || Putative protoporphyrinogen oxidase; involved in heme biosynthesis; predicted Kex2p substrate; iron regulated transcript; Yfh1-induced; Hap43-repressed; rat catheter biofilm repressed || 1 0.43 0.88 0.86 0.91 0.92 0.60 -0.11 0.09 1.26 -0.36 0.27 0.87 0.84 -0.68 -0.27 0.51
586 || orf19.4763 || || || Protein of unknown function; possibly membrane bound; mutants are viable; rat catheter biofilm repressed || 1 0.29 0.26 0.73 0.63 0.64 0.72 -0.08 0.01 0.80 -0.31 0.07 0.33 0.60 -0.44 0.14 0.19
587 || orf19.4763 || || || Protein of unknown function; possibly membrane bound; mutants are viable; rat catheter biofilm repressed || 1 0.05 0.31 0.71 0.35 0.50 0.47 -0.06 0.02 0.66 -0.31 0.05 0.29 0.60 -0.31 0.13 -0.02
588 || orf19.4763 || || || Protein of unknown function; possibly membrane bound; mutants are viable; rat catheter biofilm repressed || 1 0.17 0.40 0.86 0.36 0.47 0.49 -0.06 -0.01 0.53 -0.26 0.05 0.54 0.58 -0.21 0.14 0.03
589 || orf19.4763 || || || Protein of unknown function; possibly membrane bound; mutants are viable; rat catheter biofilm repressed || 1 0.31 0.56 1.18 0.51 0.61 0.66 -0.08 -0.04 0.48 -0.26 0.03 0.57 0.71 -0.31 0.21 0.51
590 || orf19.6100 || || || Cardiolipin synthase; ortholog of S. cerevisiae Crd1; transcript is upregulated in clinical isolates from HIV+ patients with oral candidiasis; mutants are viable; Spider biofilm repressed || 1 0.01 0.17 0.82 0.60 0.36 0.47 -0.17 0.01 0.23 0.07 0.03 0.15 0.42 -0.28 0.02 0.32
591 || orf19.2197 || || || Has domain(s) with predicted N,N-dimethylaniline monooxygenase activity, NADP binding, flavin adenine dinucleotide binding activity and role in oxidation-reduction process || 1 0.47 0.27 0.94 1.08 0.44 0.27 -0.22 0.31 0.41 -0.24 -0.30 0.17 0.40 0.15 -0.05 -0.04
592 || orf19.4168 || || || Ortholog(s) have ribonuclease MRP activity, ribonuclease P activity, role in intronic box C/D snoRNA processing, mRNA cleavage and nucleolar ribonuclease P complex, ribonuclease MRP complex localization || 1 0.84 1.13 1.32 1.51 0.49 1.42 0.32 0.16 0.69 1.09 0.24 0.12 0.90 0.81 -0.03 0.26
593 || orf19.7063 || THG1 || || tRNA guanylyltransferase, with role in tRNA modification; catalyzes reverse (3'-5') nucleotide polymerization || 1 0.30 0.41 0.74 0.54 0.05 0.60 -0.17 0.12 0.20 0.37 -0.06 -0.02 0.15 0.31 0.06 0.09
594 || orf19.3970 || || || Putative ribosome biogenesis factor; possibly essential, disruptants not obtained by UAU1 method; rat catheter and Spider biofilm induced || 1 0.61 0.56 1.84 1.24 0.31 1.00 0.28 0.38 0.12 0.85 -0.13 0.15 0.35 0.45 0.41 0.23
595 || orf19.5500 || MAK16 || || Putative constituent of 66S pre-ribosomal particles; Hap43-induced; repressed by prostaglandins; Spider biofilm induced || 1 0.32 0.26 1.25 1.45 0.27 1.11 0.55 0.41 0.68 1.07 0.08 0.25 0.64 0.05 0.30 0.53
596 || orf19.961.2 || || || Ortholog(s) have mitochondrion, nucleus localization || 1 0.20 0.25 0.91 0.80 0.28 0.74 0.37 0.65 0.79 0.84 0.19 0.67 0.48 0.04 0.16 0.17
597 || orf19.5681 || || || Ortholog of C. dubliniensis CD36 : Cd36_50190, C. parapsilosis CDC317 : CPAR2_302680, Candida tenuis NRRL Y-1498 : CANTEDRAFT_109949 and Debaryomyces hansenii CBS767 : DEHA2G00814g || 1 0.43 0.27 0.65 0.60 0.41 0.32 0.28 0.68 0.46 0.50 0.09 0.34 0.22 0.04 0.05 0.22
598 || orf19.1447 || || || Ortholog of C. dubliniensis CD36 : Cd36_16290, C. parapsilosis CDC317 : CPAR2_214050, Candida tenuis NRRL Y-1498 : CANTEDRAFT_92180 and Debaryomyces hansenii CBS767 : DEHA2A01738g || 1 0.55 0.82 1.21 1.52 0.55 0.25 0.25 0.41 1.36 0.74 0.26 0.28 1.19 -0.03 0.33 -0.23
599 || orf19.1413 || YFH1 || || Frataxin; may be required for iron storage or delivery; role in oxidative stress resistance; transcript regulated by Nrg1, repressed if iron absent induced by macrophage interaction; Hap43-repressed gene || 1 0.29 0.38 0.86 0.74 0.40 0.22 0.35 0.49 0.96 0.48 0.37 0.26 0.57 -0.29 0.10 -0.10
600 || orf19.7339 || BGL22 || || Putative glucanase; induced during cell wall regeneration || 1 0.53 0.79 1.28 1.03 0.78 0.12 0.41 0.25 1.18 0.84 0.30 0.66 0.49 0.71
601 || orf19.3260 || || || Ortholog(s) have phosphopantothenoylcysteine decarboxylase activity, role in coenzyme A biosynthetic process, response to salt stress and phosphopantothenoylcysteine decarboxylase complex localization || 1 0.21 0.79 1.04 0.85 0.34 0.65 0.60 0.35 1.00 0.40 0.31 0.07 0.20 0.39 0.48 0.40
602 || orf19.2905 || || || Ortholog of Candida albicans WO-1 : CAWG_03194 || 1 0.74 0.59 1.94 2.48 0.57 1.47 1.16 1.06 2.78 0.30 1.25 0.31 1.26 0.13 0.92 0.93
603 || orf19.4627 || || || Ortholog(s) have structural constituent of nuclear pore activity || 1 -0.07 0.02 0.88 0.64 0.13 0.35 0.38 0.38 0.68 0.14 0.69 0.29 0.24 0.20 0.39 0.11
604 || orf19.2869 || || || Ortholog of C. dubliniensis CD36 : Cd36_46110, Candida tropicalis MYA-3404 : CTRG_03792 and Candida albicans WO-1 : CAWG_03165 || 1 0.59 1.27 1.06 1.09 0.23 1.10 0.54 1.00 0.59 -0.17 1.12 0.16 0.94 0.22 0.28 0.38
605 || orf19.2195 || || || Ortholog of Candida albicans WO-1 : CAWG_05881 || 1 0.71 1.76 1.51 1.36 0.39 1.66 0.51 0.37 0.95 -0.42 0.71 -0.30 1.32 0.64 0.45 0.37
606 || orf19.7127 || TLO16 || || Member of a family of telomere-proximal genes of unknown function; may be spliced in vivo || 1 1.55 1.29 0.73 1.63 0.93 1.37 0.45 0.56 0.96 -0.20 0.20 0.05 1.06 0.61 0.33 0.34
607 || orf19.3112 || ZRT1 || || Putative zinc transporter; acts with Pra1 in sequestration of zinc from host tissues during infection; hyphal, macrophage-induced; alkaline induced upon adherence to polystyrene; induced in oralpharyngeal candidasis; Spider biofilm induced || 1 0.70 0.79 0.87 0.87 0.43 0.57 -0.20 -0.18 0.17 -0.13 0.17 -0.33 0.49 -0.38 -0.29 0.23
608 || orf19.2202 || || || Protein of unknown function; induced by alpha pheromone in SpiderM medium || 1 1.12 0.89 1.49 1.59 1.07 0.86 -0.04 -0.18 0.77 0.04 0.73 -0.67 0.83 -0.56 -0.20 -0.40
609 || orf19.5090 || || || Ortholog(s) have tRNA-specific adenosine deaminase activity, tRNA-specific adenosine-34 deaminase activity and role in adenosine to inosine editing, tRNA modification || 1 0.87 0.83 1.33 1.02 0.51 0.54 0.35 0.04 0.49 -0.18 0.63 0.12 0.61 0.06 -0.30 -0.35
610 || orf19.3107 || || || Ortholog of C. dubliniensis CD36 : Cd36_46490, Pichia stipitis Pignal : PICST_33598, Spathaspora passalidarum NRRL Y-27907 : spas_CGOB_00037 and Candida tropicalis MYA-3404 : CTRG_03758 || 1 0.81 1.51 1.71 1.59 1.68 1.32 0.43 0.35 0.88 -0.20 0.13 -0.31 0.68 -0.41 0.39 -0.42
611 || orf19.2378 || || || Ortholog(s) have role in syncytium formation by plasma membrane fusion, vacuolar proton-transporting V-type ATPase complex assembly and integral to endoplasmic reticulum membrane localization || 1 0.60 0.90 1.38 0.71 0.70 0.79 -0.18 0.09 0.71 0.09 0.12 -0.10 0.85 -0.09 -0.51 0.03
612 || orf19.3769 || || || Ortholog(s) have zinc ion transmembrane transporter activity, role in zinc ion transport and endoplasmic reticulum localization || 1 0.42 1.06 1.00 0.86 1.03 0.51 0.03 0.01 1.23 0.23 -0.20 -0.07 0.93 -0.76 -0.14 -0.40
613 || orf19.3228 || || || Putative endosomal transmembrane protein; Hap43p-induced; mutation confers hypersensitivity to amphotericin B || 1 0.45 1.18 0.95 0.89 1.25 0.41 -0.00 -0.02 1.00 0.26 -0.11 -0.17 1.16 -0.19 0.09 -0.47
614 || orf19.4815 || YTM1 || || Protein similar to S. cerevisiae Ytm1p, which is involved in biogenesis of the large ribosomal subunit; transposon mutation affects filamentous growth; protein level decreases in stationary phase cultures; Hap43p-induced gene || 1 0.49 0.95 1.27 0.88 1.02 0.83 0.16 0.17 0.93 0.36 -0.12 -0.83 1.03 0.08 0.07 -0.52
615 || orf19.2060 || SOD5 || || Cu and Zn-containing superoxide dismutase; protects against oxidative stress; induced by neutrophils, hyphal growth, caspofungin, osmotic/oxidative stress; oralpharyngeal candidiasis induced; rat catheter and Spider biofilm induced || 1 0.47 1.05 1.13 0.97 0.81 0.54 0.12 0.08 1.01 -0.23 -0.14 -0.56 0.98 0.16 0.14 -0.44
616 || orf19.2210 || || || Protein of unknown function; Spider biofilm induced || 1 0.62 1.39 0.87 1.20 0.42 0.17 0.19 -0.07 0.82 0.11 -0.32 -0.45 1.17 0.22 0.13 -0.44
617 || orf19.6170 || || || Ortholog(s) have microtubule binding, protein heterodimerization activity, protein homodimerization activity || 1 0.69 1.21 1.22 1.09 1.05 0.22 -0.05 0.17 1.03 0.12 -0.02 0.06 1.26 0.12 -0.09 -0.44
618 || orf19.4014 || || || Planktonic growth-induced gene || 1 0.78 1.45 1.51 1.27 1.11 0.34 -0.11 0.10 1.23 0.06 -0.12 -0.20 1.35 0.42 -0.19 -0.17
619 || orf19.1392 || || || Ortholog(s) have chaperone binding, protein disulfide isomerase activity, unfolded protein binding activity and role in ER-associated ubiquitin-dependent protein catabolic process, protein retention in ER lumen || 1 0.69 0.84 0.97 1.05 0.73 0.03 0.29 0.29 0.76 0.23 -0.09 -0.18 0.88 0.33 -0.05 -0.03
620 || orf19.5575 || || || Putative peripheral peroxisomal membrane peroxin; required for regulating peroxisome size and maintenance; Spider biofilm induced || 1 0.54 0.74 0.92 0.76 0.60 0.26 -0.07 -0.12 0.29 0.33 -0.03 -0.23 0.48 0.05 0.04 -0.24
621 || orf19.718 || RRN11 || || Putative RNA polymerase I subunit; rat catheter biofilm induced; Spider biofilm induced || 1 0.56 0.82 0.80 1.06 0.85 0.72 0.27 -0.20 0.52 0.31 -0.50 -0.17 0.74 0.06 -0.03 -0.31
622 || orf19.1465 || || || Has domain(s) with predicted N-acetyltransferase activity || 1 0.89 1.71 1.44 1.57 1.26 1.41 -0.08 -0.12 1.33 0.60 -0.29 -0.33 1.56 -0.16 -0.44 -0.08
623 || orf19.5039 || RRP42 || || Putative exosome non-catalytic core component; involved in 3'-5' RNA processing; rat catheter biofilm induced || 1 0.56 1.14 1.36 1.04 1.00 1.30 -0.04 -0.18 1.15 0.85 -0.34 -0.16 1.36 0.15 -0.41 -0.20
624 || orf19.1040 || MAD2 || || Protein required for the spindle assembly checkpoint of the cell cycle; necessary for survival in host cell macrophages and for virulence in a mouse model of systemic candidiasis || 1 0.15 0.84 1.32 1.16 0.70 1.17 -0.19 -0.39 1.08 0.81 -0.08 -0.06 0.95 0.14 -0.45 -0.28
625 || orf19.6777 || || || Ortholog of Candida albicans WO-1 : CAWG_03032 || 1 0.42 0.77 0.94 0.78 0.22 0.96 0.04 -0.06 0.76 -0.07 0.18 -0.03 0.65 0.09 -0.10 -0.11
626 || orf19.344 || || || Protein of unknown function; upregulated by fluphenazine treatment or in an azole-resistant strain that overexpresses CDR1 and CDR2; transcript possibly regulated by Tac1 || 1 1.26 1.07 1.51 1.22 1.00 1.33 -0.14 -0.32 1.03 0.00 -0.21 0.11 0.96 0.36 -0.59 -0.43
627 || orf19.278 || || || Protein of unknown function; required for adhesion to abiotic substrate; Spider biofilm induced || 1 0.66 0.59 1.14 0.82 0.52 1.04 0.16 -0.31 0.62 -0.30 -0.41 0.28 0.63 -0.15 -0.28 -0.25
628 || orf19.5266 || || || Planktonic growth-induced gene || 1 0.45 0.95 1.33 1.05 0.77 0.78 -0.33 -0.70 0.63 -0.33 -0.67 -0.34 0.80 -0.09 -0.55 0.28
629 || orf19.1515 || CHT4 || || Chitinase; similar to S. cerevisiae sporulation-specific Cts2p; functionally complements A. gossypii cts2 mutant sporulation defect; homozygous null mutation causes no obvious defects; transcription decreases upon yeast-to-hyphal switch || 1 0.35 0.86 1.12 0.94 0.76 0.82 -0.37 -0.46 0.57 -0.43 -0.50 0.04 0.72 -0.02 -0.13 0.12
630 || orf19.530 || || || Protein with a UV radiation resistance protein/autophagy-related protein 14 domain; Hap43p-induced gene; mutants are viable || 1 1.08 1.20 1.48 1.20 0.94 0.83 -0.48 -0.39 0.92 -0.10 -0.28 0.11 0.84 -0.00 -0.26 0.07
631 || orf19.530 || || || Protein with a UV radiation resistance protein/autophagy-related protein 14 domain; Hap43p-induced gene; mutants are viable || 1 0.94 1.20 1.42 1.18 0.95 0.61 -0.38 -0.48 0.69 0.02 -0.61 0.05 1.18 -0.04 -0.37 -0.05
632 || orf19.530 || || || Protein with a UV radiation resistance protein/autophagy-related protein 14 domain; Hap43p-induced gene; mutants are viable || 1 0.95 1.21 1.13 1.23 0.75 0.52 -0.29 -0.25 0.72 -0.03 -0.44 0.13 0.80 -0.25 -0.49 -0.22
633 || orf19.479.2 || SEC22 || || Ortholog(s) have SNAP receptor activity and role in ER to Golgi vesicle-mediated transport, retrograde vesicle-mediated transport, Golgi to ER, vesicle fusion with Golgi apparatus || 1 0.45 0.64 0.77 0.76 0.54 0.21 -0.24 -0.20 0.16 -0.17 -0.26 -0.04 0.42 -0.09 -0.06 -0.06
634 || orf19.875 || || || Protein required for respiratory growth || 1 0.06 0.59 0.79 0.66 0.69 0.45 -0.54 -0.38 0.66 -0.06 -0.46 0.24 0.82 0.04 -0.15 -0.17
635 || orf19.6953 || IRS4 || || Protein with roles in cell wall integrity, systemic (but not oral) murine infection, adherence, hyphal growth, and agar-embedded filamentous growth; antigenic in human infection; similar to S. cerevisiae Irs4p || 1 0.22 0.88 1.27 1.45 0.89 0.89 -0.41 -0.45 0.92 -0.03 -0.36 0.24 1.23 0.06 -0.06 -0.01
636 || orf19.7095 || || || Ortholog(s) have endoplasmic reticulum localization || 1 0.05 0.80 0.95 1.11 1.00 0.65 -0.32 -0.31 0.95 -0.45 -0.22 0.29 1.03 -0.04 0.02 0.15
637 || orf19.3876 || ZCF19 || || Predicted Zn(II)2Cys6 transcription factor || 1 0.37 0.80 1.23 0.99 0.99 0.67 -0.26 -0.55 1.10 -0.36 -0.53 0.12 1.16 -0.20 -0.17 0.03
638 || orf19.2213 || || || Ortholog(s) have cytoplasm, nucleus localization || 1 0.25 0.80 1.37 0.92 1.14 0.73 -0.17 -0.41 1.54 0.09 -0.39 0.25 1.20 0.08 -0.19 0.05
639 || orf19.4366 || || || Ortholog of C. dubliniensis CD36 : Cd36_28870, Candida tropicalis MYA-3404 : CTRG_00731 and Candida albicans WO-1 : CAWG_01703 || 1 0.56 1.22 1.77 1.26 0.79 0.86 -0.33 -0.23 1.87 0.17 -0.63 0.38 1.09 -0.07 -0.31 -0.01
640 || orf19.3954 || PSD2 || || Ortholog(s) have phosphatidylserine decarboxylase activity, role in phosphatidylcholine biosynthetic process, phosphatidylethanolamine biosynthetic process and cell division site, cytosol, endosome localization || 1 0.18 0.73 0.95 1.10 0.66 0.84 -0.21 -0.32 0.99 -0.06 -0.11 0.59 0.69 0.18 0.08 -0.00
641 || orf19.4210 || || || Ortholog(s) have phospholipase A2 activity, role in cardiolipin acyl-chain remodeling and mitochondrion localization || 1 0.39 0.93 1.04 1.45 0.73 0.85 -0.04 -0.30 1.29 -0.22 -0.33 0.07 1.23 -0.06 0.07 -0.58
642 || orf19.3772 || || || Predicted ORF in Assemblies 19, 20 and 21; merged with orf19.3773 in Assembly 21 || 1 0.45 0.57 0.90 0.77 0.71 0.23 0.15 0.13 0.38 -0.16 -0.03 0.10 0.60 0.06 0.27 0.04
643 || orf19.2925 || || || Ortholog(s) have role in protein folding, tubulin complex assembly and cytoplasm localization || 1 0.95 1.32 1.24 1.39 0.79 0.63 0.24 0.30 1.20 -0.06 0.35 -0.03 0.93 0.15 0.20 -0.04
644 || orf19.6512 || EXO70 || || Predicted subunit of the exocyst complex, involved in exocytosis; localizes to a crescent on the surface of the hyphal tip || 1 0.78 1.03 1.05 1.03 0.71 0.43 0.16 0.33 0.65 0.10 -0.05 0.08 1.04 -0.08 0.48 -0.21
645 || orf19.4748 || || || Putative U2B'' component of the U2 snRNP, involved in splicing; contains an RNA recognition motif (RRM); ortholog of S. cerevisiae MSL1; Hap43p-induced gene || 1 0.90 1.33 1.63 1.83 1.25 0.74 0.35 0.32 1.36 -0.29 0.13 0.27 1.37 -0.27 0.25 -0.48
646 || orf19.5462 || || || Protein of unknown function || 1 0.73 1.34 1.18 1.58 1.13 0.76 0.16 0.08 0.93 -0.37 0.02 -0.13 1.19 -0.52 0.21 -0.52
647 || orf19.5462 || || || Protein of unknown function || 1 0.32 0.57 1.10 1.45 0.68 0.77 -0.10 0.37 0.54 -0.47 -0.09 -0.06 0.64 -0.36 0.06 -0.24
648 || orf19.5462 || || || Protein of unknown function || 1 0.42 0.84 1.27 1.52 1.02 0.91 0.10 0.23 0.52 -0.46 -0.10 -0.03 0.93 -0.17 0.32 -0.30
649 || orf19.3279 || HYR4 || || Putative GPI-anchored adhesin-like protein; Rim101-repressed; constitutive expression independent of MTL or white-opaque status || 1 0.31 0.40 0.66 0.90 0.60 0.51 -0.01 0.14 0.49 -0.40 0.00 0.07 0.59 0.03 0.15 -0.05
650 || orf19.1679 || || || Ortholog of C. dubliniensis CD36 : Cd36_81550, C. parapsilosis CDC317 : CPAR2_503570, Candida tenuis NRRL Y-1498 : cten_CGOB_00261 and Debaryomyces hansenii CBS767 : DEHA2D15378g || 1 0.31 0.71 1.47 1.51 0.70 0.70 -0.04 -0.12 0.59 -0.34 -0.23 0.10 0.72 0.12 0.37 -0.16
651 || orf19.5502 || || || Ortholog of C. dubliniensis CD36 : Cd36_73420, Debaryomyces hansenii CBS767 : DEHA2A05456g, Pichia stipitis Pignal : PICST_30999 and Candida guilliermondii ATCC 6260 : PGUG_00155 || 1 0.60 0.68 1.37 1.51 1.21 1.17 -0.02 0.13 0.64 0.18 -0.11 -0.18 0.86 0.01 0.14 -0.05
652 || orf19.6589 || SSF1 || || Protein involved in ribosome biogenesis; ortholog of S. cerevisiae Ssf1; Hap43-induced; rat catheter and Spider biofilm induced || 1 0.55 0.86 1.43 1.65 0.88 1.36 0.15 -0.09 0.67 0.33 -0.28 -0.34 1.03 0.00 -0.04 -0.45
653 || orf19.2508 || PRM9 || || Protein described a similar to S. cerevisiae Prm9; not the ortholog though; mutant is viable || 1 0.34 0.61 1.37 1.23 0.71 0.44 -0.01 -0.06 0.70 0.01 -0.17 -0.18 0.65 0.04 -0.12 -0.26
654 || orf19.7379 || FAA2 || || Putative acyl CoA synthetase; expression regulated upon white-opaque switch; rat catheter biofilm induced; Spider biofilm induced || 1 0.28 0.47 0.98 0.73 0.45 0.54 -0.10 -0.27 0.67 -0.14 -0.41 -0.00 0.71 0.10 -0.12 -0.27
655 || orf19.1741 || DIT1 || || Ortholog(s) have catalytic activity and role in ascospore wall assembly || 1 0.39 0.71 1.45 1.09 0.55 1.14 -0.23 -0.19 0.89 -0.19 -0.27 -0.02 0.79 0.17 -0.15 -0.43
656 || orf19.6502 || || || Short-chain dehydrogenase/reductase; upregulation correlates with clinical development of fluconazole resistance || 1 0.45 0.91 1.68 1.12 1.03 1.14 -0.23 -0.08 0.83 -0.37 -0.37 0.11 1.02 0.09 -0.27 -0.47
657 || orf19.2394 || || || Ortholog(s) have cytoplasm, nucleus localization || 1 0.27 0.75 1.63 1.50 0.87 1.14 -0.21 -0.30 0.77 -0.65 -0.47 -0.13 1.14 -0.38 -0.03 0.10
658 || orf19.4652 || || || Protein of unknown function; rat catheter biofilm induced || 1 0.83 1.20 2.21 2.07 1.03 1.61 -0.26 -0.26 1.08 -0.28 -0.38 -0.14 1.05 -0.42 -0.16 -0.25
659 || orf19.10711 || PIKALPHA || || Putative phosphatidylinositol kinase; non-sex gene located within the MTLalpha mating-type-like locus || 1 0.68 0.96 1.25 1.33 0.73 1.08 -0.14 -0.22 0.99 -0.27 -0.42 -0.43 0.92 -0.35 -0.19 -0.17
660 || orf19.1855 || || || Predicted membrane transporter, member of the anion:cation symporter (ACS) family, major facilitator superfamily (MFS); Gcn4p-regulated; flucytosine induced; ketoconazole-repressed; oxidative stress-induced via Cap1p || 1 1.33 1.35 1.73 2.05 0.94 1.20 -0.20 -0.18 1.20 -0.09 -0.32 0.05 0.70 0.06 -0.00 0.20
661 || orf19.2552 || || || Protein similar to S. cerevisiae Pmr1p; amphotericin B induced; previously merged with orf19.2553; unmerged from orf19.2553 in a revision of Assembly 21 || 1 1.62 1.73 2.42 2.32 1.48 1.47 -0.18 -0.14 1.88 -0.16 -0.22 0.21 1.11 -0.07 -0.14 0.21
662 || orf19.848 || PGA16 || || Putative GPI-anchored protein || 1 1.40 1.72 2.12 2.58 1.49 1.74 -0.14 -0.31 1.95 -0.04 -0.27 0.22 1.45 -0.26 0.23 -0.26
663 || orf19.6248 || || || Ortholog of C. dubliniensis CD36 : Cd36_06210, Candida tropicalis MYA-3404 : CTRG_04227 and Candida albicans WO-1 : CAWG_00750 || 1 0.88 1.13 1.40 1.42 0.99 1.01 -0.44 -0.12 1.36 -0.19 -0.21 -0.10 0.90 -0.15 -0.19 0.27
664 || orf19.1659 || ALG8 || || Putative glucosyltransferase involved in cell wall mannan biosynthesis; transcription is elevated in nik1 and sln1 homozygous null mutants, but not in the chk1 null mutant; possibly an essential gene, disruptants not obtained by UAU1 method || 1 0.95 1.13 1.20 1.14 1.13 0.97 -0.23 -0.05 1.26 0.00 -0.17 0.15 1.06 0.03 0.15 0.13
665 || orf19.3818 || GOA1 || || Protein required for respiratory growth, resistance to oxidants, chlamydospore formation, hyphal growth under some conditions, and virulence; relocalizes from the cytoplasm to the mitochondrion during oxidative or osmotic stress || 1 0.94 1.22 1.48 1.30 1.21 1.17 -0.04 -0.03 1.02 -0.35 -0.02 0.17 0.97 -0.24 0.07 -0.15
666 || orf19.2103 || || || Ortholog of Candida albicans WO-1 : CAWG_03811 || 1 0.58 1.18 1.56 1.51 1.25 1.11 -0.13 -0.12 1.43 -0.42 -0.38 -0.01 1.18 -0.01 0.13 0.26
667 || orf19.4652 || || || Protein of unknown function; rat catheter biofilm induced || 1 1.03 1.29 2.03 1.83 1.26 1.18 0.10 0.26 1.52 -0.01 -0.17 -0.32 1.21 -0.30 0.13 -0.53
668 || orf19.4481 || MFALPHA || || Alpha factor mating pheromone precursor; three copies of pheromone that are proteolytically processed by Kex2p and possibly by Orf19.5851p; required for alpha cells to mate; expressed specifically in opaque phase MTLalpha/MTLalpha cells || 1 1.05 1.38 2.66 2.41 1.30 1.65 -0.21 0.03 2.09 0.17 -0.42 0.33 1.50 -0.10 -0.18 -0.66
669 || orf19.2509 || || || Ortholog of C. parapsilosis CDC317 : CPAR2_401850, C. dubliniensis CD36 : Cd36_80970, Lodderomyces elongisporus NRLL YB-4239 : LELG_04407 and Candida orthopsilosis Co 90-125 : CORT_0E01890 || 1 0.73 1.43 1.47 2.23 1.15 0.80 -0.32 0.07 1.63 -0.17 -0.20 0.24 1.30 -0.00 -0.02 -0.19
670 || orf19.3898 || || || Ortholog(s) have SNAP receptor activity, role in endocytosis, vesicle fusion and Golgi apparatus, SNARE complex, endoplasmic reticulum, endosome, trans-Golgi network localization || 1 0.68 1.45 1.38 1.85 1.28 0.83 0.02 0.04 1.41 0.02 0.10 0.32 1.35 -0.02 0.24 -0.06
671 || orf19.6811 || ISA2 || || Protein required for maturation of mitochondrial [4Fe-4S] proteins; role in biotin biosynthetic process; rat catheter and Spider biofilm induced || 1 1.31 1.52 2.98 2.47 1.83 1.10 0.31 0.14 1.34 0.14 0.21 0.10 1.15 0.21 0.86 0.09
672 || orf19.1762 || OCA1 || || Putative protein phosphatase of the PTP family (tyrosine-specific); ortholog of S. cerevisiae Oca1; mutant is viable; mutant shows virulence defect || 1 0.67 0.87 1.17 1.14 0.88 0.69 0.07 -0.03 0.43 0.12 -0.02 0.17 0.66 -0.06 0.23 0.05
673 || orf19.2211 || || || Ortholog of C. dubliniensis CD36 : Cd36_21990, C. parapsilosis CDC317 : CPAR2_103660, Debaryomyces hansenii CBS767 : DEHA2F19756g and Pichia stipitis Pignal : PICST_61375 || 1 0.90 1.18 1.74 1.89 1.07 0.98 0.14 0.12 1.11 -0.03 -0.13 0.21 1.13 0.02 0.27 0.46
674 || orf19.3172 || || || Ortholog of C. dubliniensis CD36 : Cd36_51840, Candida tropicalis MYA-3404 : CTRG_05315 and Candida albicans WO-1 : CAWG_04584 || 1 1.07 1.43 2.20 2.35 1.53 1.18 0.39 0.42 1.65 -0.04 0.06 0.43 1.39 0.44 0.30 0.09
675 || orf19.7555 || || || Ortholog of Candida albicans WO-1 : CAWG_02247 || 1 0.42 0.94 1.75 1.75 0.77 1.01 0.19 0.07 0.94 -0.19 0.13 0.40 0.82 0.12 0.29 -0.00
676 || orf19.1524 || SPR3 || || Septin; mutant has no obvious phenotype || 1 0.59 1.40 1.78 1.69 1.33 1.17 -0.13 -0.02 1.32 0.22 -0.15 0.41 1.40 0.37 0.06 0.19
677 || orf19.6064 || || || Ortholog(s) have phosphatidylinositol binding, ubiquitin binding activity || 1 0.70 0.94 1.97 1.28 1.05 1.16 -0.18 -0.03 1.00 0.11 -0.07 0.09 1.18 0.37 0.07 0.29
678 || orf19.1968 || || || Ortholog of C. dubliniensis CD36 : Cd36_51280, C. parapsilosis CDC317 : CPAR2_501840, Candida tenuis NRRL Y-1498 : cten_CGOB_00020 and Debaryomyces hansenii CBS767 : DEHA2F24310g || 1 0.08 0.64 1.29 1.19 0.79 0.90 -0.03 0.03 0.70 0.17 -0.08 0.48 0.63 0.07 0.05 -0.05
679 || orf19.7557 || FGR46 || || Protein lacking an ortholog in S. cerevisiae; transposon mutation affects filamentous growth || 1 0.45 0.71 2.00 1.55 1.02 0.97 -0.16 -0.01 1.10 0.20 -0.01 0.88 0.75 0.48 -0.09 0.01
680 || orf19.647.3 || || || Protein of unknown function; Spider biofilm induced || 1 0.58 0.60 1.76 1.38 0.56 0.71 -0.07 -0.14 1.11 0.06 -0.14 0.14 0.66 0.06 0.10 0.35
681 || orf19.6179 || || || Ortholog of Candida albicans WO-1 : CAWG_03090 || 1 0.60 0.83 2.97 2.13 0.90 1.95 0.01 -0.07 1.70 0.55 -0.18 0.23 1.09 -0.04 -0.06 0.50
682 || orf19.1304 || || || Ortholog(s) have role in U4 snRNA 3'-end processing, exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA and LSU-rRNA), more || 1 0.59 0.92 2.21 1.91 1.12 1.81 -0.18 -0.31 1.35 0.39 -0.38 0.12 1.17 0.12 -0.02 -0.12
683 || orf19.3908 || MRV8 || || Protein of unknown function; Spider biofilm induced || 1 0.33 0.96 2.61 2.09 1.26 1.97 -0.25 -0.15 2.32 0.28 -0.20 0.31 0.56 0.13 0.37 0.36
684 || orf19.2415 || || || Ortholog(s) have role in mitochondrial translation and mitochondrion localization || 1 0.87 1.17 1.44 0.86 1.29 0.97 0.25 0.19 1.09 0.24 -0.11 0.16 1.18 -0.09 0.19 -0.28
685 || orf19.1969 || CCW14 || || Putative mannoprotein of cell wall with role in response to stress; increased mRNA abundance observed in cyr1 homozygous mutant (hyphal or yeast-form cells) and in ras1 homozygous mutant (yeast-form cells) || 1 0.80 1.71 1.82 1.66 1.76 2.26 0.12 0.10 1.76 -0.03 0.43 1.66 0.37 -0.05
686 || orf19.6431 || || || Protein of unknown function; Spider biofilm induced || 1 0.41 0.61 0.99 0.61 0.70 0.84 0.14 0.09 0.42 0.40 -0.01 0.36 0.70 0.33 0.16 -0.06
687 || orf19.3304 || || || Exosome non-catalytic core component; involved in 3'-5' RNA processing and degradation in the nucleus and cytoplasm; Spider biofilm induced || 1 0.85 0.91 1.37 1.22 1.09 1.16 0.15 0.33 0.47 0.37 0.20 0.23 0.77 -0.05 0.38 0.04
688 || orf19.5046 || RAM1 || || Protein that acts in prenylation; transcription is alpha-factor induced; regulated in response to lovastatin and fluconazole; Hap43p-repressed gene || 1 0.44 0.58 0.75 0.67 0.35 0.45 0.05 0.13 0.29 0.28 0.04 0.37 0.40 0.07 0.18 0.08
689 || orf19.6024 || || || Ortholog of C. dubliniensis CD36 : Cd36_00770, Candida tenuis NRRL Y-1498 : CANTEDRAFT_112621, Debaryomyces hansenii CBS767 : DEHA2D09812g and Pichia stipitis Pignal : PICST_61958 || 1 0.61 0.54 0.64 0.73 0.38 0.46 0.37 -0.02 0.36 -0.05 0.03 0.21 0.73 0.26 0.31 0.42
690 || orf19.2400 || || || Ortholog(s) have role in mRNA splicing, via spliceosome, maturation of SSU-rRNA, positive regulation of ATPase activity, positive regulation of helicase activity || 1 0.99 0.65 0.93 1.05 0.44 0.76 0.30 -0.03 0.94 -0.07 0.25 0.54 0.73 0.26 0.43 0.23
691 || orf19.3848 || || || Ortholog of C. dubliniensis CD36 : Cd36_31420, C. parapsilosis CDC317 : CPAR2_205100, Debaryomyces hansenii CBS767 : DEHA2G10648g and Pichia stipitis Pignal : PICST_32997 || 1 0.61 0.70 1.12 0.85 0.70 0.80 0.16 -0.01 0.48 -0.15 0.11 0.42 0.56 -0.12 0.73 0.41
692 || orf19.728 || TSC11 || || Protein similar to S. cerevisiae Tsc11p which is involved in sphingolipid biosynthesis; transposon mutation affects filamentous growth || 1 0.52 0.61 0.82 0.84 0.49 0.54 -0.01 -0.02 0.48 -0.17 0.03 0.30 0.29 0.23 0.34 0.20
693 || orf19.4776 || LYS143 || || Zn(II)2Cys6 transcription factor; ortholog of S. cerevisiae Lys14 involved in the regulation of lysine biosynthesis genes || 1 1.02 0.83 1.43 1.22 0.81 0.92 0.57 0.24 1.32 -0.15 0.20 0.09 0.90 0.16 0.53 0.45
694 || orf19.700 || SEO1 || || Protein with similarity to permeases; Sfu1-repressed; flucytosine induced; induced by Mnl1 under weak acid stress; flow model biofilm repressed || 1 1.14 1.18 1.65 1.92 0.96 1.61 -0.05 0.01 1.19 -0.11 0.35 0.27 0.63 0.27 0.14 1.23
695 || orf19.553 || || || Predicted membrane transporter, member of the drug:proton antiporter (12 spanner) (DHA1) family, major facilitator superfamily (MFS) || 1 1.54 1.23 2.95 2.91 1.35 2.15 -0.00 0.05 2.17 0.33 0.62 1.23 1.76 0.39 0.03 1.92
696 || orf19.647.3 || || || Protein of unknown function; Spider biofilm induced || 1 0.81 1.09 1.67 1.86 0.79 1.14 0.17 0.19 1.65 0.37 0.25 0.32 0.99 0.22 0.32 0.49
697 || orf19.5424 || || || Ortholog of Candida albicans WO-1 : CAWG_02376 || 1 0.95 1.01 1.59 1.70 1.00 1.26 0.08 0.10 1.49 0.15 0.32 0.38 0.74 0.13 0.29 0.73
698 || orf19.6453 || || || Ortholog of C. dubliniensis CD36 : Cd36_72300, C. parapsilosis CDC317 : CPAR2_703060, Candida tenuis NRRL Y-1498 : CANTEDRAFT_92002 and Debaryomyces hansenii CBS767 : DEHA2B06028g || 1 1.14 1.05 1.55 1.28 1.19 1.21 -0.14 0.03 1.29 -0.03 0.32 0.31 1.19 -0.15 0.35 0.67
699 || orf19.4466 || || || Ortholog(s) have palmitoyltransferase activity and role in ascospore formation, cellular response to cadmium ion, detoxification of cadmium ion, protein palmitoylation, protein targeting to membrane || 1 1.53 1.23 2.31 2.05 1.19 1.92 -0.16 -0.17 2.09 0.26 0.36 0.46 1.54 -0.02 0.14 1.29
700 || orf19.1062 || || || Ortholog of C. dubliniensis CD36 : Cd36_04020, C. parapsilosis CDC317 : CPAR2_107000, Candida tenuis NRRL Y-1498 : CANTEDRAFT_113990 and Pichia stipitis Pignal : PICST_32780 || 1 1.17 1.11 1.89 1.88 1.24 1.46 -0.17 -0.00 1.57 -0.12 0.11 -0.01 1.07 -0.33 -0.04 0.92
701 || orf19.4409 || || || Ortholog(s) have nucleoside-triphosphatase activity, nucleoside-triphosphate diphosphatase activity and role in cellular response to phosphate starvation, nucleoside triphosphate metabolic process || 1 0.69 0.81 1.59 1.13 0.84 1.20 -0.08 -0.12 1.21 -0.06 0.02 0.03 0.91 -0.18 0.25 0.58
702 || orf19.4905 || || || Putative MFS transporter; Hap43p-induced gene; also regulated by regulated by Sef1p and Sfu1p; repressed in a ssr1 null mutant || 1 0.82 0.72 1.45 1.36 0.82 0.86 -0.12 0.12 0.85 -0.47 0.08 0.16 1.07 0.28 0.16 0.48
703 || orf19.7206 || OCA6 || || Putative protein phosphatase of the PTP family (tyrosine-specific), similar to S. cerevisiae Oca6p; mutant shows virulence defect || 1 0.77 0.73 1.07 0.98 1.04 0.71 -0.12 -0.09 0.67 -0.12 0.10 0.17 0.57 -0.02 0.05 0.39
704 || orf19.530 || || || Protein with a UV radiation resistance protein/autophagy-related protein 14 domain; Hap43p-induced gene; mutants are viable || 1 1.29 1.21 1.37 1.34 0.96 0.78 -0.30 -0.30 0.88 -0.11 0.46 0.09 0.80 0.29 -0.11 0.52
705 || orf19.2103 || || || Ortholog of Candida albicans WO-1 : CAWG_03811 || 1 1.15 1.07 1.80 1.36 0.94 0.50 -0.12 0.03 0.51 -0.03 0.32 0.03 0.98 0.02 0.08 0.65
706 || orf19.2326 || || || Ortholog(s) have role in chromatin silencing at silent mating-type cassette, double-strand break repair via homologous recombination, intra-S DNA damage checkpoint, mitotic sister chromatid cohesion and nucleus localization || 1 1.34 1.45 1.64 1.38 1.18 0.89 0.28 0.33 1.13 0.09 0.62 0.27 0.86 0.10 0.43 0.92
707 || orf19.1563 || ECM3 || || Ortholog(s) have endoplasmic reticulum localization || 1 0.79 0.91 0.94 0.98 0.98 0.68 0.25 0.38 0.62 -0.11 0.41 0.57 0.99 0.07 0.56 0.33
708 || orf19.1107 || || || Protein of unknown function; Spider biofilm induced || 1 0.73 1.02 0.95 0.80 0.96 0.74 0.19 0.12 0.82 -0.19 0.40 0.42 0.90 0.19 0.39 0.69
709 || orf19.1798 || TSC2 || || Putative GTPase-activating protein; similar to mammalian tuberin; involved in control of filamentous growth; mutants are viable || 1 1.36 1.14 1.49 1.40 1.40 1.55 0.12 -0.10 1.10 -0.32 0.37 0.42 1.27 -0.05 0.64 0.61
710 || orf19.1333 || SNG3 || || Putative membrane transporter; Hap43p-induced gene; mutation confers hypersensitivity to toxic ergosterol analog; shows colony morphology-related gene regulation by Ssn6p || 1 1.40 1.37 1.34 1.39 1.51 1.62 0.15 0.14 0.97 -0.28 0.57 0.17 1.15 -0.43 0.54 1.54
711 || orf19.3459 || || || Putative serine/threonine/tyrosine (dual-specificity) kinase; disruptants not obtained by UAU1 method || 1 1.15 0.86 1.11 0.93 0.64 0.57 -0.13 0.13 0.80 -0.02 0.51 0.38 0.96 0.11 0.02 0.89
712 || orf19.136 || || || Predicted membrane transporter, member of the drug:proton antiporter (12 spanner) (DHA1) family, major facilitator superfamily (MFS); Hap43p-repressed gene || 1 1.12 1.26 1.78 1.52 1.14 0.98 0.22 0.14 0.64 -0.70 0.33 0.08 1.35 -0.46 0.20 1.04
713 || orf19.5462 || || || Protein of unknown function || 1 0.82 0.97 1.29 1.41 0.86 0.73 0.05 0.28 0.65 -0.38 0.22 -0.07 0.88 -0.54 0.35 0.38
714 || orf19.7395 || || || Ortholog of Candida albicans WO-1 : CAWG_02922 || 1 0.46 1.07 1.13 0.98 0.78 0.51 0.15 0.16 0.64 0.25 0.28 0.34 0.41 -0.27 0.14 -0.21
715 || orf19.2399 || || || Putative transcription factor with zinc finger DNA-binding motif; similar to bacterial DnaJ; induced in low iron || 1 0.31 1.09 1.19 1.39 1.01 0.88 0.37 0.30 0.88 0.23 0.32 0.39 0.32 -0.05 0.27 0.11
716 || orf19.5520 || ASG7 || || a-cell specific protein of unknown function; two predicted transmembrane domains; member of conserved Mcm1 regulon; induced by alpha pheromone in SpiderM medium || 1 0.76 0.88 1.54 1.69 0.72 0.86 0.23 0.05 0.76 0.08 0.61 0.38 0.57 0.24 0.13 -0.06
717 || orf19.2995 || || || Protein of unknown function; induced by nitric oxide; rat catheter and Spider biofilm induced || 1 0.78 0.74 1.06 1.00 0.79 0.54 -0.25 0.01 0.13 0.23 -0.09 0.15 0.53 -0.22 0.11 -0.24
718 || orf19.7406 || || || Ortholog of C. dubliniensis CD36 : Cd36_86220, C. parapsilosis CDC317 : CPAR2_404490, Candida tenuis NRRL Y-1498 : CANTEDRAFT_94473 and Debaryomyces hansenii CBS767 : DEHA2D01804g || 1 0.74 0.47 0.82 0.84 0.59 0.62 0.01 -0.14 0.11 0.17 -0.18 0.02 0.30 -0.15 0.01 0.22
719 || orf19.1327 || RBT1 || || Cell wall protein with similarity to Hwp1; required for virulence; predicted glycosylation; fluconazole, Tup1 repressed; farnesol, alpha factor, serum, hyphal and alkaline induced; Rfg1, Rim101-regulated || 1 1.11 0.69 1.91 1.86 1.77 1.03 0.07 -0.17 0.39 0.00 -0.12 -0.19 0.64 -0.35 0.25 0.13
720 || orf19.5011 || KAR9 || || Ortholog of S. cerevisiae Kar9; role in mitotic spindle positioning; nonessential; localizes to bud tip, bud neck, hyphal tip; wild-type localization requires actin and microtubule cytoskeleton; induced by alpha factor || 1 0.34 0.43 0.62 0.54 0.67 0.67 0.01 -0.17 0.05 0.05 -0.16 0.14 0.29 -0.14 0.11 -0.06
721 || orf19.7170 || || || Ortholog of C. dubliniensis CD36 : Cd36_73740, Candida tropicalis MYA-3404 : CTRG_05151 and Candida albicans WO-1 : CAWG_05736 || 1 0.69 0.79 1.39 1.38 1.04 1.59 -0.32 -0.52 0.28 0.11 -0.40 -0.03 0.73 0.19 0.49 0.12
722 || orf19.6530 || || || Similar to bacterial DnaJ; transcript upregulated in low iron; flow model biofilm induced; Spider biofilm induced || 1 0.55 0.49 1.34 1.25 0.79 0.95 -0.19 -0.34 0.49 -0.29 -0.32 0.09 0.56 -0.01 0.44 0.34
723 || orf19.7033 || || || Putative dual specificity protein phosphatase, similar to S. cerevisiae Pps1p || 1 0.41 0.63 1.19 1.04 0.61 0.79 -0.30 -0.05 0.09 -0.31 -0.17 0.09 0.63 0.10 0.26 0.39
724 || orf19.3112 || ZRT1 || || Putative zinc transporter; acts with Pra1 in sequestration of zinc from host tissues during infection; hyphal, macrophage-induced; alkaline induced upon adherence to polystyrene; induced in oralpharyngeal candidasis; Spider biofilm induced || 1 0.61 0.86 1.61 1.56 0.69 0.36 0.20 0.49 1.18 0.11 0.01 0.48 0.78 -0.07 0.17 0.45
725 || orf19.5237 || VPH2 || || Ortholog(s) have role in vacuolar acidification, vacuolar proton-transporting V-type ATPase complex assembly and endoplasmic reticulum membrane localization || 1 0.39 0.28 0.97 0.60 0.61 0.23 0.02 0.24 0.73 0.05 -0.06 -0.03 0.54 0.01 0.16 0.41
726 || orf19.849 || || || Ortholog(s) have role in protein N-linked glycosylation, protein O-linked glycosylation, response to stress || 1 0.78 1.19 2.33 1.53 1.51 1.60 0.42 0.07 2.20 0.39 0.20 0.73 1.58 0.97 0.27 0.37
727 || orf19.3204 || || || Ortholog of C. dubliniensis CD36 : Cd36_51610, C. parapsilosis CDC317 : CPAR2_303630, Candida tenuis NRRL Y-1498 : CANTEDRAFT_135125 and Debaryomyces hansenii CBS767 : DEHA2E19030g || 1 0.21 0.74 2.01 1.80 0.86 1.43 0.18 -0.15 1.31 0.89 -0.08 0.61 0.92 0.63 0.33 0.62
728 || orf19.4498 || || || Ortholog of C. dubliniensis CD36 : Cd36_19120, C. parapsilosis CDC317 : CPAR2_103880, Candida tenuis NRRL Y-1498 : CANTEDRAFT_115581 and Debaryomyces hansenii CBS767 : DEHA2F08426g || 1 0.38 0.59 1.32 1.05 0.39 1.09 0.41 0.01 0.85 0.52 -0.24 0.36 0.57 0.87 0.08 0.14
729 || orf19.217 || || || Ortholog(s) have sequence-specific DNA binding activity || 1 0.65 1.11 1.64 1.80 0.85 2.00 -0.10 -0.19 2.46 0.58 -0.42 0.38 0.98 -0.01 -0.26
730 || orf19.647.3 || || || Protein of unknown function; Spider biofilm induced || 1 0.20 0.66 1.58 1.35 0.67 1.10 -0.08 -0.26 1.79 0.22 -0.44 0.35 0.96 0.36 -0.08 -0.07
731 || orf19.1548 || || || Ortholog(s) have role in mRNA splicing, via spliceosome and U4/U6 x U5 tri-snRNP complex localization || 1 0.29 0.95 1.33 1.11 0.43 0.88 0.08 0.08 1.49 0.31 -0.27 0.32 0.83 0.43 -0.39 -0.37
732 || orf19.3042 || || || Protein of unknown function; Hap43-induced; rat catheter biofilm induced || 1 0.37 1.03 1.61 1.19 0.48 0.84 -0.07 -0.16 1.70 0.06 -0.03 0.57 1.24 0.43 -0.67 0.08
733 || orf19.1314 || || || Protein of unknown function; planktonic growth-induced gene || 1 0.42 0.88 0.94 0.51 0.94 0.72 -0.18 -0.14 0.77 -0.52 0.07 0.60 0.90 0.10 0.11 0.60
734 || orf19.5871 || SNF5 || || SWI/SNF chromatin remodeling complex subunit involved in transcriptional regulation; mutants have defects in silicone adherence, biofilm formation, hyphal morphogenesis, cell wall defects; increased cell aggregation during yeast form growth || 1 0.35 0.61 0.60 0.44 0.71 0.40 -0.01 -0.06 0.57 -0.11 0.22 0.38 0.75 0.34 0.16 0.20
735 || orf19.2671 || || || Protein with a predicted FAD-dependent pyridine nucleotide reductase domains; putative oxidoreductase; Plc1-regulated; possibly an essential gene, disruptants not obtained by UAU1 method || 1 0.59 1.20 1.00 0.90 1.37 0.76 0.06 -0.08 0.82 -0.65 0.27 0.26 1.27 0.76 0.20 0.56
736 || orf19.6057 || || || Ortholog(s) have 3-methyl-2-oxobutanoate hydroxymethyltransferase activity, role in pantothenate biosynthetic process, respiratory chain complex IV assembly and mitochondrion localization || 1 0.25 0.92 1.04 0.60 0.91 0.58 0.05 -0.01 1.04 -0.13 -0.02 -0.13 1.02 0.33 -0.02 0.19
737 || orf19.5045 || PTP2 || || Predicted protein tyrosine phosphatase; involved in regulation of MAP kinase Hog1 activity; induced by Mnl1 under weak acid stress; rat catheter and Spider biofilm induced || 1 0.37 1.04 1.08 1.07 1.13 0.80 -0.04 -0.09 1.16 -0.04 0.35 -0.09 1.02 0.40 0.56 0.46
738 || orf19.5045 || PTP2 || || Predicted protein tyrosine phosphatase; involved in regulation of MAP kinase Hog1 activity; induced by Mnl1 under weak acid stress; rat catheter and Spider biofilm induced || 1 0.55 1.22 0.92 0.92 1.33 0.70 -0.03 -0.06 1.11 -0.04 0.45 -0.06 1.02 0.43 0.66 0.36
739 || orf19.5045 || PTP2 || || Predicted protein tyrosine phosphatase; involved in regulation of MAP kinase Hog1 activity; induced by Mnl1 under weak acid stress; rat catheter and Spider biofilm induced || 1 0.65 1.39 0.86 1.30 1.24 0.65 -0.01 -0.05 1.17 -0.03 0.21 -0.23 0.98 0.37 0.65 0.15
740 || orf19.2246 || || || Ortholog(s) have cytosol, nucleus localization || 1 0.95 1.48 1.13 1.50 0.64 0.44 0.21 0.17 0.70 0.54 0.43 0.24 0.98 0.31 0.18 -0.30
741 || orf19.3676 || ABP140 || || Ortholog of S. cerevisiae actin-binding protein Abp140; Hap43-induced; F-12/CO2 early biofilm induced || 1 1.46 1.62 1.60 1.54 0.54 1.01 0.22 0.50 1.43 0.86 -0.01 -0.05 0.78 0.25 0.38 -0.17
742 || orf19.5270 || || || Protein of unknown function; rat catheter biofilm induced || 1 1.40 1.29 1.54 1.48 0.46 -0.14 0.13 0.35 1.20 0.66 -0.28 -0.22 0.44 0.16 0.06 -0.09
743 || orf19.799 || STE4 || || Beta subunit of heterotrimeric G protein of mating signal transduction pathway; required for mating; transcript is specific to cells homozygous at MTL; induced by alpha pheromone; ortholog of S. cerevisiae Ste4 || 1 1.92 0.91 1.18 1.81 0.73 0.70 0.24 0.06 1.55 0.29 -0.52 -0.53 1.00 -0.09 0.19 -0.65
744 || orf19.6955 || HBR3 || || Essential protein; regulated by hemoglobin; S. cerevisiae ortholog is essential; Hap43p-induced gene || 1 1.89 0.94 1.19 2.12 0.77 1.36 0.24 0.03 1.52 0.87 -0.33 -0.15 0.89 0.41 0.17 -0.70
745 || orf19.6908 || || || Dihydrofolate synthetase involved in folic acid biosynthesis || 1 2.16 1.21 1.81 2.54 1.10 1.23 0.23 0.51 1.92 0.12 0.07 0.37 1.47 0.02 0.39 -0.00
746 || orf19.781 || DUR31 || || High affinity spermidine transporter; expression is induced by urea; fungal-specific (no human or murine homolog); not required for virulence in a mouse intravenous model || 1 2.22 1.11 1.56 2.70 0.94 1.56 0.37 0.03 2.45 0.24 0.11 0.49 0.96 0.10 0.06 0.03
747 || orf19.90 || || || Ortholog(s) have cytoplasm localization || 1 2.28 1.29 1.36 2.83 1.00 1.62 0.15 0.13 2.21 0.19 -0.31 -0.03 1.02 0.37 0.05 -0.09
748 || orf19.6685 || ISY1 || || Putative pre-mRNA-splicing factor; mutation confers resistance to 5-fluorocytosine (5-FC); rat catheter biofilm induced || 1 1.65 0.84 1.38 2.52 0.83 1.49 0.14 -0.18 2.24 0.01 -0.31 0.45 0.54 0.23 -0.47 -0.34
749 || orf19.7024 || || || Ortholog of Candida albicans WO-1 : CAWG_05448 || 1 1.22 1.13 1.21 1.83 0.01 0.72 -0.11 0.09 1.32 -0.07 -0.06 0.35 0.16 -0.33 0.11 -0.08
750 || orf19.6284 || || || Ortholog(s) have GTP binding, signal recognition particle binding activity, role in protein targeting to ER and integral to endoplasmic reticulum membrane localization || 1 1.27 0.63 0.80 1.80 0.44 0.35 -0.06 -0.03 0.75 -0.05 -0.26 0.19 0.43 -0.22 0.37 0.05
751 || orf19.2907 || PGA42 || || Putative GPI-anchored adhesin-like protein; decreased transcription is observed in azole-resistant strains that overexpress CDR1 and CDR2 or MDR1 || 1 0.81 0.86 1.29 2.35 0.55 0.82 0.76 1.23 1.07 -0.33 0.07 -0.02 0.67 0.05 0.16 0.94
752 || orf19.1531 || || || Ortholog(s) have RNA binding, protein heterodimerization activity, role in mRNA cleavage, mRNA polyadenylation and cytosol, mRNA cleavage factor complex, mitochondrion localization || 1 1.61 0.86 1.52 1.72 0.76 0.55 1.28 1.50 1.09 -0.04 0.19 0.07 0.89 -0.22 0.55 -0.27
753 || orf19.4194 || || || Putative TFIIH complex subunit; possibly an essential gene, disruptants not obtained by UAU1 method || 1 1.67 0.89 1.57 1.66 0.71 0.95 0.69 1.76 1.81 0.49 0.49 0.16 1.23 -0.09 0.61 -0.55
754 || orf19.641 || || || Ortholog(s) have role in protein folding and endoplasmic reticulum localization || 1 1.61 0.48 1.38 1.54 0.26 0.63 0.60 0.81 1.10 0.56 0.11 -0.02 0.47 -0.34 0.32 -0.59
755 || orf19.10711 || PIKALPHA || || Putative phosphatidylinositol kinase; non-sex gene located within the MTLalpha mating-type-like locus || 1 0.57 0.80 1.14 1.10 0.17 0.30 -0.10 0.20 0.44 -0.19 0.03 0.09 0.18 -0.10 -0.18 0.05
756 || orf19.1341 || PRR2 || || Putative serine/threonine protein kinase; mutation confers resistance to 5-fluorocytosine (5-FC) || 1 1.43 1.28 2.17 2.09 0.04 1.16 0.31 0.32 0.99 -0.17 -0.08 0.03 0.29 -0.32 -0.20 -0.24
757 || orf19.3925 || || || Putative protein of unknown function, transcription is activated in the presence of elevated CO2 || 1 1.04 0.88 1.33 1.61 0.61 1.20 0.28 0.31 0.49 -0.11 -0.30 -0.20 0.62 -0.38 -0.04 0.02
758 || orf19.1757 || || || Putative C2H2 transcription factor; expression upregulated in clinical isolates from HIV+ patients with oral candidiasis; Spider biofilm induced || 1 1.86 0.72 2.03 1.84 0.34 1.25 0.41 0.44 0.96 0.33 -0.08 -0.26 0.51 -0.35 0.14 -0.43
759 || orf19.6820 || || || Has domain(s) with predicted protein heterodimerization activity, role in DNA-dependent transcription, initiation and transcription factor TFIID complex localization || 1 0.46 0.44 0.68 0.63 0.13 0.34 0.07 0.16 0.61 0.09 -0.14 0.03 0.32 -0.13 0.18 -0.11
760 || orf19.217 || || || Ortholog(s) have sequence-specific DNA binding activity || 1 2.01 1.34 2.75 2.82 1.03 2.00 0.50 0.99 2.32 0.01 -0.59 -0.13 1.04 -0.39 0.50 -0.58
761 || orf19.3241 || || || Ortholog(s) have Seh1-associated complex, extrinsic to fungal-type vacuolar membrane localization || 1 0.55 0.73 1.28 1.25 0.17 0.85 0.31 0.37 0.79 -0.13 -0.35 -0.11 0.34 -0.11 0.14 -0.31
762 || orf19.4652 || || || Protein of unknown function; rat catheter biofilm induced || 1 1.11 1.78 2.62 2.36 0.34 1.61 0.50 0.80 1.73 0.08 -0.01 -0.44 1.01 -0.22 0.27 -0.60
763 || orf19.586 || ERV46 || || Putative ER-derived vesicle protein; COPII-coated vesicle complex subunit; transcript induced by filamentous growth; Spider biofilm repressed || 1 0.73 1.05 1.73 1.89 0.58 0.89 0.50 0.74 1.17 0.13 -0.05 -0.07 0.46 -0.43 0.29 -0.14
764 || orf19.7625 || PGA1 || || Putative GPI-anchored protein; induced during cell wall regeneration; required for normal adhesion to host cells and for adherence during Sabouraud biofilm formation; Spider biofilm induced || 1 0.98 1.16 2.12 1.98 0.96 1.33 0.88 1.11 1.50 0.36 -0.15 0.11 0.84 -0.31 0.62 -0.47
765 || orf19.2264 || OLE2 || || Protein with similarity to fatty acid desaturase (stearoyl-CoA desaturase); homozygous null mutant shows decreased production of prostaglandin E2 || 1 0.67 0.38 1.72 1.40 0.59 1.04 0.33 0.57 0.83 0.03 -0.27 -0.17 0.48 -0.08 0.31 -0.18
766 || orf19.3774 || PPG1 || || Putative protein phosphatase of the Type 2A-related family (serine/threonine-specific), similar to S. cerevisiae Ppg1p; possibly an essential gene, disruptants not obtained by UAU1 method || 1 1.04 0.45 1.82 1.82 0.17 1.01 0.63 0.67 1.30 0.27 -0.16 0.06 0.55 -0.05 0.31 -0.18
767 || orf19.7546 || || || Protein involved in rRNA processing; required for maturation of the 35S primary transcript of pre-rRNA and for cleavage leading to mature 18S rRNA; Spider biofilm induced || 1 1.59 0.64 2.36 2.30 0.47 1.64 0.54 0.92 1.73 0.46 -0.58 -0.67 0.49 -0.48 0.29 -0.54
768 || orf19.3220 || || || Putative rRNA processing protein; Spider biofilm induced || 1 1.12 1.19 1.97 2.04 0.54 1.44 0.51 0.41 0.89 0.19 -0.44 -0.43 0.68 0.04 -0.07 -0.69
769 || orf19.3691 || TIM21 || || Component of the Translocase of the Inner Mitochondrial membrane (TIM23 complex); for protein import into mitochondria; Hap43, ketoconazole-repressed; Spider biofilm repressed || 1 0.63 0.61 1.64 1.57 0.28 0.68 0.19 0.34 0.79 0.38 -0.54 -0.05 0.49 0.03 0.04 -0.35
770 || orf19.6488 || || || Ortholog of C. dubliniensis CD36 : Cd36_72050, C. parapsilosis CDC317 : CPAR2_301140, Candida tenuis NRRL Y-1498 : CANTEDRAFT_135055 and Debaryomyces hansenii CBS767 : DEHA2E07678g || 1 1.42 1.06 2.62 2.52 0.65 1.24 0.13 -0.09 2.15 0.03 -0.54 0.35 0.97 -0.09 -0.04 -0.53
771 || orf19.3863 || || || Ortholog of C. dubliniensis CD36 : Cd36_31580, C. parapsilosis CDC317 : CPAR2_205000, Debaryomyces hansenii CBS767 : DEHA2G10846g and Pichia stipitis Pignal : PICST_32988 || 1 0.98 0.80 2.68 2.44 0.38 1.52 0.09 0.13 1.87 0.09 -0.08 0.09 0.74 -0.06 -0.03 -0.11
772 || orf19.3229 || || || Protein of unknown function; transcript detected on high-resolution tiling arrays || 1 1.54 1.33 2.14 2.99 0.74 1.44 0.42 0.34 1.97 0.15 0.25 0.38 0.85 -0.22 0.59 0.27
773 || orf19.7648 || || || Has domain(s) with predicted antiporter activity, drug transmembrane transporter activity, role in drug transmembrane transport and membrane localization || 1 0.93 0.94 1.72 2.03 0.80 1.07 0.63 0.25 1.03 0.09 0.15 0.47 0.74 -0.60 0.44 -0.07
774 || orf19.3626 || || || Ortholog(s) have cytosol, nucleus localization || 1 0.28 0.97 2.01 1.76 1.04 1.22 0.45 0.30 1.28 0.30 -0.02 -0.07 0.58 -0.16 0.16 -0.61
775 || orf19.3557 || GPI19 || || Subunit of GPI-GlcNAc transferase; role in synthesis of N-acetylglucosaminyl phosphatidylinositol (GlcNAc-PI), the first intermediate in GPI anchor synthesis; complements S. cerevisiae gpi19 mutant; flow model biofilm induced || 1 0.32 0.35 1.24 0.89 0.66 1.00 0.37 0.22 0.74 0.08 0.55 0.05 0.66 0.51 -0.11
776 || orf19.6730 || || || Ortholog(s) have nucleolus localization || 1 0.38 0.72 1.79 1.67 0.62 1.18 0.61 0.44 0.81 0.63 0.47 0.10 1.03 0.42 0.41 0.31
777 || orf19.275 || || || Ortholog(s) have RNA binding, ribonuclease MRP activity, ribonuclease P activity, role in intronic box C/D snoRNA processing, mRNA cleavage and endoplasmic reticulum, nucleolar ribonuclease P complex, ribonuclease MRP complex localization || 1 0.40 0.27 1.08 1.14 0.54 0.78 0.32 0.77 0.16 -0.00 0.22 0.02 0.56 0.06 0.21 0.17
778 || orf19.6460 || PEX1 || || Ortholog(s) have ATPase activity, protein heterodimerization activity, role in fatty acid metabolic process, protein import into peroxisome matrix, receptor recycling and cytosol, peroxisomal membrane localization || 1 0.52 0.47 1.13 1.33 0.77 0.57 0.79 0.92 0.70 0.34 0.30 0.14 0.76 0.21 0.69 0.65
779 || orf19.6552 || || || Flavin-linked sulfhydryl oxidase; predicted localization to endoplasmic reticulum lumen; involved in disulfide bond formation within the ER; Spider biofilm induced || 1 0.67 0.49 1.31 1.03 0.80 0.81 0.87 0.85 0.86 0.25 0.55 0.48 0.50 0.36 0.84 0.89
780 || orf19.7670 || || || Putative Ca2+/H+ antiporter; oral infection upregulated gene; mutants have reduced capacity to damage oral epithelial cells || 1 1.60 1.32 2.53 2.95 1.34 2.20 1.69 1.80 2.24 -0.21 0.95 0.55 1.34 0.23 1.03 1.79
781 || orf19.6166 || || || Ortholog of C. dubliniensis CD36 : Cd36_80810, C. parapsilosis CDC317 : CPAR2_101800, Candida tenuis NRRL Y-1498 : CANTEDRAFT_103482 and Debaryomyces hansenii CBS767 : DEHA2F17864g || 1 1.18 1.10 2.53 2.33 0.95 1.25 1.14 1.13 0.84 0.22 0.44 0.37 0.76 0.04 0.94 1.21
782 || orf19.1355 || || || Putative protein of unknown function; stationary phase enriched protein || 1 0.68 0.33 1.35 1.18 0.58 1.07 0.70 0.59 0.47 -0.05 0.43 0.42 0.63 0.03 0.98 0.72
783 || orf19.6016 || || || Ortholog(s) have GTPase activity, calcium ion binding activity, role in mitochondrion inheritance, phospholipid homeostasis, regulation of mitochondrion organization and ERMES complex, cytosol, nuclear envelope localization || 1 0.36 0.65 1.35 1.20 0.87 0.79 0.35 0.44 0.86 -0.27 0.26 0.29 0.84 -0.22 0.26 0.35
784 || orf19.2585 || || || Ortholog of Candida albicans WO-1 : CAWG_01548 || 1 0.64 0.51 1.84 1.33 0.86 1.37 0.40 0.67 1.24 -0.05 0.48 0.42 0.75 0.23 0.13 0.40
785 || orf19.4964 || || || Ortholog(s) have role in cellular bud site selection, mRNA export from nucleus, mRNA splicing, via spliceosome and RES complex localization || 1 1.00 0.78 1.33 1.57 1.01 1.90 0.67 0.46 0.91 0.09 0.80 0.31 0.84 0.23 0.65 0.11
786 || orf19.4146 || SMD3 || || Putative core snRNP protein; induced upon adherence to polystyrene || 1 0.80 1.07 1.36 1.34 0.83 1.18 0.50 0.70 0.73 0.16 0.74 0.38 0.49 0.31 0.50 0.28
787 || orf19.6732 || || || Ortholog(s) have cytosol, nucleus localization || 1 0.48 0.79 1.21 1.25 0.86 1.07 0.44 0.54 0.68 0.11 0.29 0.13 0.33 0.31 0.14 0.43
788 || orf19.2786 || || || Ortholog(s) have AP-2 adaptor complex, cellular bud neck localization || 1 2.12 1.22 2.53 2.28 0.94 1.77 1.16 1.45 1.88 0.51 -0.25 -0.08 0.84 0.19 0.84 -0.07
789 || orf19.3344 || VPS17 || || Ortholog(s) have phosphatidylinositol-3-phosphate binding, protein transporter activity || 1 1.57 1.43 1.69 1.46 0.78 1.08 0.80 1.06 0.96 0.09 0.19 -0.04 0.88 0.01 0.47 -0.24
790 || orf19.647.3 || || || Protein of unknown function; Spider biofilm induced || 1 0.79 1.63 2.34 2.67 1.04 1.73 0.79 1.01 1.99 -0.03 0.82 -0.03 1.06 0.17 0.55 -0.33
791 || orf19.705 || GCN5 || || Putative histone acetyltransferase; mutation confers hypersensitivity to 5-fluorouracil (5-FU); possibly an essential gene, disruptants not obtained by UAU1 method || 1 0.89 1.22 1.95 1.90 0.73 1.32 0.72 1.21 0.89 0.22 0.36 -0.34 0.89 -0.06 0.40 -0.01
792 || orf19.7022 || || || Ortholog of C. dubliniensis CD36 : Cd36_70850, Candida tenuis NRRL Y-1498 : cten_CGOB_00183, Debaryomyces hansenii CBS767 : DEHA2F22462g and Pichia stipitis Pignal : PICST_60416 || 1 1.22 1.29 2.22 2.57 1.28 1.75 1.38 1.42 1.42 -0.11 0.74 0.28 1.38 0.63 0.64 0.59
793 || orf19.5467 || TLO7 || || Member of a family of telomere-proximal genes of unknown function; may be spliced in vivo; rat catheter biofilm repressed || 1 1.75 1.12 1.97 1.87 0.83 1.53 0.99 1.07 1.09 0.08 0.94 0.06 1.21 0.61 0.77 0.36
794 || orf19.7343 || || || Ortholog(s) have role in mRNA splicing, via spliceosome and U4/U6 x U5 tri-snRNP complex localization || 1 1.24 0.44 1.66 1.47 0.45 0.86 0.57 0.45 0.83 0.22 0.73 0.16 0.84 0.20 0.63 0.19
795 || orf19.7205 || DUR7 || || Putative urea transporter; fungal-specific (no human or murine homolog) || 1 2.37 1.08 2.29 2.32 1.12 1.96 1.43 1.35 1.82 0.22 1.15 0.23 0.96 0.03 1.23 0.23
796 || orf19.4771 || || || Protein of unknown function; Spider biofilm induced || 1 1.61 0.68 2.42 2.09 0.60 1.76 1.44 1.15 1.61 0.35 1.05 -0.02 0.78 0.01 1.17 0.11
797 || orf19.4955 || || || Ortholog(s) have role in ascospore wall assembly and endoplasmic reticulum, mitochondrion localization || 1 1.63 1.11 2.90 3.19 1.36 2.29 1.43 1.26 2.14 0.54 1.39 0.55 1.26 -0.01 1.44 -0.29
798 || orf19.4064 || GPI7 || || Protein involved in attachment of GPI-linked proteins to cell wall; member of major facilitator superfamily; phosphodiesterase/nucleotide pyrophosphatase domain; similar to S. cerevisiae Gpi7p || 1 1.38 0.88 2.75 2.23 0.79 1.59 1.37 1.15 1.82 0.68 0.94 -0.26 0.91 -0.06 0.76 -0.44
799 || orf19.7489.3 || || || Ortholog(s) have role in negative regulation of transcription from RNA polymerase II promoter in response to iron and cytosol, nucleus localization || 1 1.21 1.12 2.46 2.53 0.75 1.46 1.02 1.10 1.58 0.59 0.38 0.23 1.02 0.38 0.80 0.02
800 || orf19.5312 || MET4 || || Putative transcription coactivator; predicted role in sulfur amino acid metabolism; required for yeast cell adherence to silicone substrate; Spider biofilm induced || 1 1.24 0.92 2.44 2.35 0.69 1.77 0.85 1.18 1.44 0.27 0.28 -0.08 1.11 -0.04 0.70 -0.23
801 || orf19.2412 || || || Ortholog(s) have role in late endosome to vacuole transport via multivesicular body sorting pathway and Golgi apparatus, Vps55/Vps68 complex, fungal-type vacuole membrane, late endosome localization || 1 1.22 1.02 1.82 2.01 0.38 1.09 0.74 1.03 0.84 0.06 0.35 0.30 1.14 0.11 0.58 -0.11
802 || orf19.2367 || || || Putative protein of unknown function; Hap43-induced; repressed by Rim101; Spider biofilm induced || 1 1.18 1.06 2.20 2.57 0.81 1.50 1.22 0.83 1.15 0.09 0.74 0.48 1.39 -0.08 0.97 0.22
803 || orf19.5042 || || || Ortholog(s) have role in maintenance of rDNA and nuclear periphery localization || 1 0.96 0.72 1.97 2.11 0.81 1.03 0.68 0.66 1.10 0.17 0.79 0.35 0.78 0.00 0.22 0.41
804 || orf19.2044 || PGA27 || || Putative GPI-anchored protein || 1 1.34 1.23 2.95 2.67 0.96 2.03 1.03 1.01 1.80 -0.05 1.15 0.26 1.31 0.11 0.56 0.26
805 || orf19.2411 || SYN8 || || Putative endosomal SNARE; role in protein transport; rat catheter and Spider biofilm induced || 1 0.73 0.74 1.79 1.63 0.43 1.03 0.56 0.72 0.83 -0.22 0.55 0.00 0.80 0.02 0.23 0.37
806 || orf19.7549 || PMT5 || || Protein mannosyltransferase (PMT), expressed at extremely low levels; not required for wild-type hyphal growth, drug resistance, or virulence in mouse systemic infection; one of five PMT family members || 1 0.59 0.32 1.51 1.25 0.28 0.69 0.81 0.81 1.01 0.18 0.69 -0.00 0.63 0.08 0.25 0.11
807 || orf19.7622 || SPT3 || || Functional homolog of S. cerevisiae Spt3p; required for virulence in mouse systemic infection; homozygous null mutant is hyperfilamentous || 1 0.52 0.25 1.41 1.30 0.37 0.80 0.28 0.58 0.66 -0.04 0.33 -0.09 0.47 -0.03 0.18 -0.18
808 || orf19.7068 || MAC1 || || Copper fist transcription factor; regulator of CTR1 copper transporter; induces CTR1 in low-copper conditions; ectopic expression causes copper-sensitive stimulation of filamentation in S. cerevisiae; Spider biofilm induced || 1 0.60 0.66 1.82 1.88 0.74 1.54 0.63 0.90 1.17 -0.49 0.41 -0.41 0.64 -0.28 0.35 -0.16
809 || orf19.1581 || || || Planktonic growth-induced gene || 1 0.56 0.70 1.76 2.18 0.53 1.48 0.58 0.79 1.03 -0.44 0.05 0.18 0.50 0.10 0.23 0.34
810 || orf19.2072 || || || Ortholog(s) have (R)-carnitine transmembrane transporter activity, choline transmembrane transporter activity, ethanolamine transmembrane transporter activity || 1 0.63 0.29 1.96 2.46 0.59 1.61 0.59 0.65 1.26 -0.70 0.21 0.22 1.08 -0.52 0.38 0.21
811 || orf19.445 || || || Protein of unknown function; repressed by prostaglandins || 1 0.48 0.31 1.31 1.42 0.60 0.86 0.69 0.58 0.41 -0.15 0.07 0.11 0.49 -0.40 0.29 0.08
812 || orf19.3098 || || || Predicted RNA-dependent ATPase RNA helicase; Hap43-induced gene || 1 0.80 0.51 1.54 1.69 0.80 1.35 0.69 0.70 0.72 -0.03 0.56 -0.16 0.86 -0.67 0.71 0.33
813 || orf19.3120 || || || PDR-subfamily ABC transporter (half-size); similar to WHITE subfamily proteins; repressed by fluphenazine treatment or in an azole-resistant strain that overexpresses CDR1 and CDR2; induced by nitric oxide; rat catheter biofilm induced || 1 1.25 0.98 2.90 3.26 0.97 2.12 0.95 1.25 1.95 -0.58 1.03 0.04 0.74 -0.45 1.39 0.91
814 || orf19.1075 || || || Protein of unknown function; Spider biofilm induced || 1 1.38 1.06 2.12 2.62 1.20 2.13 1.22 1.22 1.23 -0.75 0.88 0.16 1.06 -0.49 1.23 0.87
815 || orf19.4358 || || || Putative protein of unknown function; Hap43p-repressed gene; S. cerevisiae ortholog YDL157C localizes to mitochondria || 1 0.82 0.72 1.53 1.70 0.90 1.52 0.75 0.78 0.96 -0.78 0.25 -0.02 0.69 -0.43 0.81 0.68
816 || orf19.3910 || || || Has domain(s) with predicted RNA binding, ribonuclease T2 activity || 1 0.60 0.58 1.37 1.74 0.60 0.97 0.48 0.23 0.64 -0.68 0.39 0.19 0.45 -0.60 0.37 0.44
817 || orf19.4985 || GUP1 || || Putative O-acyltransferase with a role in glycerol uptake; functionally complements growth of S. cerevisiae gup1 mutant under salt stress; required for normal ergosterol distribution, hyphal growth, biofilm formation || 1 0.79 0.65 1.45 1.38 1.24 0.57 0.42 0.62 0.69 -0.07 0.23 0.16 0.43 -0.26 0.29 -0.22
818 || orf19.4295 || || || Ortholog(s) have DNA binding, nucleosome binding, transcription corepressor activity || 1 0.77 0.70 1.74 1.78 0.69 0.87 0.52 0.77 0.89 -0.09 -0.09 0.35 0.64 0.11 0.23 -0.15
819 || orf19.5155 || CHS6 || || Protein with tetratricopeptide repeats (TPRs); ortholog of S. cerevisiae Chs6, which has role in localizing chitin synthase; Cyr1-regulated in hyphae; possibly essential, disruptants not obtained by UAU1 method; flow model biofilm repressed || 1 0.57 0.67 1.38 1.22 0.80 0.39 0.61 0.64 0.83 0.03 0.28 0.14 0.66 0.17 0.19 -0.15
820 || orf19.1581 || || || Planktonic growth-induced gene || 1 0.61 0.79 1.78 1.44 0.45 0.54 0.43 0.73 0.89 0.12 0.34 -0.06 0.37 0.12 0.17 -0.24
821 || orf19.6786 || || || Protein of unknown function; flow model biofilm induced || 1 0.30 0.88 1.79 1.68 0.67 0.41 0.33 0.43 0.87 -0.13 0.16 0.33 0.37 0.03 0.06 -0.32
822 || orf19.3901 || || || Putative benzene desulfurase; induced by nitric oxide independent of Yhb1p || 1 0.43 0.42 1.20 1.78 0.01 0.42 0.34 0.57 0.49 -0.32 -0.07 0.11 0.51 0.09 0.25 0.22
823 || orf19.2899 || || || Ortholog(s) have cytosol, nucleus localization || 1 0.89 0.46 1.66 1.94 0.40 0.58 0.59 0.60 0.32 -0.35 -0.00 -0.10 0.48 -0.45 0.25 0.37
824 || orf19.1587 || HGT20 || || Putative glucose transporter of the major facilitator superfamily; the C. albicans glucose transporter family comprises 20 members; 12 probable membrane-spanning segments; regulated by Nrg1 || 1 0.60 0.55 1.76 1.96 0.68 0.98 0.64 0.42 0.41 -0.15 -0.17 -0.52 0.44 -0.11 0.42 0.12
825 || orf19.2215 || GLE1 || || Putative nucleoporin; moderately induced at 42 degrees C || 1 0.39 0.60 1.36 1.47 0.52 0.74 0.37 0.49 0.30 0.10 -0.02 -0.01 0.39 0.07 0.37 0.07
826 || orf19.5713 || YMX6 || || Putative NADH dehydrogenase; macrophage-downregulated gene; induced by nitric oxide; rat catheter biofilm induced || 1 0.88 0.85 1.40 1.50 0.46 0.74 0.32 0.41 0.23 -0.11 0.03 -0.05 0.45 0.16 0.50 0.34
827 || orf19.2825 || DRE2 || || Putative cytosolic Fe-S protein assembly protein; a-specific transcript; regulated by Sef1, Sfu1, and Hap43; rat catheter and Spider biofilm induced || 1 0.76 0.99 1.74 1.62 0.49 0.53 0.43 0.38 0.12 -0.26 0.09 0.44 0.51 -0.05 0.57 0.62
828 || orf19.115 || || || Ortholog of Candida tropicalis MYA-3404 : CTRG_02973 and Candida albicans WO-1 : CAWG_05252 || 1 0.55 0.70 2.17 1.99 0.38 0.53 0.19 0.30 0.56 0.08 -0.15 0.16 0.44 -0.20 0.25 0.51
829 || orf19.6998 || GTT1 || || Putative glutathione S-transferase; downregulated upon adherence to polystyrene; regulated upon white-opaque switching; induced in the presence of human neutrophils; oxidative stress-induced via Cap1p; regulated by Gcn2p, Gcn4p || 1 0.78 0.92 2.01 1.92 0.55 0.44 0.48 0.48 0.46 0.12 0.34 0.04 0.43 -0.07 0.37 0.44
830 || orf19.1780 || || || Has domain(s) with predicted catalytic activity || 1 0.97 0.87 2.47 2.27 0.68 0.60 0.74 0.97 1.08 0.25 -0.03 -0.13 0.80 -0.04 0.50 0.93
831 || orf19.2544 || || || Ortholog(s) have aminoacyl-tRNA hydrolase activity, role in negative regulation of proteasomal ubiquitin-dependent protein catabolic process and mitochondrial outer membrane localization || 1 0.88 0.89 1.45 1.22 0.80 0.55 0.86 1.10 0.62 0.10 0.25 0.13 0.84 0.07 0.86 0.32
832 || orf19.344 || || || Protein of unknown function; upregulated by fluphenazine treatment or in an azole-resistant strain that overexpresses CDR1 and CDR2; transcript possibly regulated by Tac1 || 1 1.51 1.39 2.21 2.47 1.68 0.56 1.22 1.57 0.59 -0.06 0.63 -0.35 1.41 -0.25 0.89 0.87
833 || orf19.1451 || SRB9 || || Subunit of the RNA polymerase II mediator complex; transposon mutation affects filamentous growth; suppresses S. cerevisiae diploid filamentous (flo8, ste7, ste12, tec1) or haploid invasive (flo8) mutant growth defects || 1 0.63 0.79 0.76 1.41 0.71 0.41 0.68 0.88 0.48 -0.20 0.16 0.01 0.60 0.06 0.41 -0.07
834 || orf19.123 || RCN1 || || Protein involved in calcineurin-dependent signaling that controls stress response and virulence; inhibits calcineurin function || 1 0.47 0.34 0.98 1.15 0.55 0.45 0.45 0.35 0.21 0.37 0.13 0.19 0.36 0.08 0.41 0.19
835 || orf19.703 || || || Ortholog(s) have 2',3'-cyclic-nucleotide 3'-phosphodiesterase activity, role in cyclic nucleotide metabolic process and clathrin-coated vesicle localization || 1 0.66 0.82 1.49 1.23 0.61 0.60 0.44 0.26 0.80 -0.25 -0.11 0.12 0.74 0.43 0.46 -0.14
836 || orf19.3581 || || || Ortholog(s) have histone binding activity, role in DNA replication-dependent nucleosome assembly and CAF-1 complex, cytoplasm, nucleus localization || 1 0.56 0.56 0.91 1.00 0.08 0.51 0.52 0.49 0.63 0.29 0.50 0.19 0.26 -0.25 0.22 0.02
837 || orf19.4340.1 || || || Ortholog(s) have role in mRNA splicing, via spliceosome and U1 snRNP, U2 snRNP, U4/U6 x U5 tri-snRNP complex, U5 snRNP, cytosol localization || 1 0.44 0.48 1.11 0.88 0.33 0.13 0.54 0.56 0.47 0.66 0.65 0.15 0.93 0.53 0.47 0.22
838 || orf19.6013 || || || Ortholog(s) have cytosol, nucleolus localization || 1 0.45 0.76 0.79 0.94 0.35 0.33 0.38 0.64 0.56 0.70 0.92 0.30 1.15 0.51 0.81 0.05
839 || orf19.473 || TPO4 || || Putative sperimidine transporter; fungal-specific (no human or murine homolog); Spider biofilm induced; promoter bound by Tec1 and Ndt80; Bcr1-repressed in RPMI a/a biofilms || 1 0.99 1.05 1.13 1.05 0.75 0.53 0.88 0.88 1.00 0.30 0.49 -0.15 1.08 0.33 1.01 -0.33
840 || orf19.3963 || || || Ortholog(s) have mitochondrion localization || 1 0.62 0.72 0.86 0.75 0.38 0.43 0.35 0.55 0.44 0.32 0.19 0.21 0.67 0.38 0.30 -0.19
841 || orf19.4573 || ZCF26 || || Zn2-Cys6 transcription factor of unknown function; induced by alpha pheromone in SpiderM medium || 1 0.88 0.81 1.10 0.69 0.32 0.14 0.29 0.55 0.62 0.52 0.16 0.13 0.41 0.28 0.39 0.04
842 || orf19.6064 || || || Ortholog(s) have phosphatidylinositol binding, ubiquitin binding activity || 1 0.91 0.83 0.94 0.88 0.41 0.03 0.12 0.53 0.26 0.32 0.41 0.04 0.21 0.14 0.35 0.21
843 || orf19.6437 || CDC23 || || Similar to anaphase-promoting complex component; possibly transcriptionally regulated by Tac1p || 1 0.48 0.40 0.56 0.44 0.22 0.10 0.11 0.31 0.21 0.04 0.31 -0.01 0.34 0.09 0.37 0.29
844 || orf19.2677 || || || Putative GPI transamidase component; possibly an essential gene, disruptants not obtained by UAU1 method || 1 0.43 0.32 0.72 0.54 0.46 0.23 0.15 0.25 0.43 0.03 0.36 -0.10 0.48 0.34 0.35 0.31
845 || orf19.1715 || IRO1 || || Putative transcription factor; role in iron utilization, pathogenesis; both IRO1 and adjacent URA3 are mutated in strain CAI4; suppresses S. cerevisiae aft1 mutant low-iron growth defect; hyphal-induced; reports differ about iron regulation || 1 0.74 0.88 1.02 0.94 0.58 0.10 0.40 0.45 0.74 0.35 0.20 0.09 0.89 0.22 0.23 0.81
846 || orf19.7022 || || || Ortholog of C. dubliniensis CD36 : Cd36_70850, Candida tenuis NRRL Y-1498 : cten_CGOB_00183, Debaryomyces hansenii CBS767 : DEHA2F22462g and Pichia stipitis Pignal : PICST_60416 || 1 1.16 1.31 1.62 1.40 1.16 0.53 0.26 0.60 1.01 0.23 0.45 0.25 1.41 0.54 0.49 0.70
847 || orf19.5919 || MEA1 || || Protein similar to A. nidulans MesA, which is involved in localization of actin cables; Hap43p-induced gene || 1 1.12 0.83 1.39 1.22 0.66 0.50 0.19 0.47 1.12 0.59 0.21 0.20 0.79 0.22 0.70 0.59
848 || orf19.497 || EAF7 || || Subunit of the NuA4 histone acetyltransferase complex || 1 1.03 0.81 1.29 1.33 0.83 0.86 0.55 0.70 0.91 0.57 0.32 0.25 1.15 0.58 0.62 0.41
849 || orf19.4167 || || || Protein of unknown function; Spider biofilm induced || 1 0.71 0.88 0.98 1.28 0.57 0.72 0.44 0.68 0.75 0.49 0.63 0.51 0.92 0.50 0.51 0.33
850 || orf19.7109 || || || Ortholog(s) have role in meiosis and cytosol, nucleus localization || 1 0.70 0.55 0.87 0.94 0.50 0.32 0.05 0.47 0.62 0.25 0.33 0.28 0.28 0.51 0.49 0.17
851 || orf19.4830 || || || Ortholog of C. dubliniensis CD36 : Cd36_09110, C. parapsilosis CDC317 : CPAR2_803660, Candida tenuis NRRL Y-1498 : cten_CGOB_00140 and Debaryomyces hansenii CBS767 : DEHA2B12056g || 1 0.80 0.82 1.53 1.57 0.33 0.56 0.69 0.67 0.57 0.41 0.29 0.10 0.95 0.57 0.15 0.33
852 || orf19.4447 || YMC1 || || Putative inner mitochondrial membrane transporter; flucytosine induced; Spider biofilm repressed || 1 0.97 0.88 1.19 1.71 0.53 0.57 1.00 1.04 0.80 0.57 0.25 -0.01 0.85 0.25 0.21 0.42
853 || orf19.2940 || || || Putative v-SNARE of the endoplasmic reticulum membrane; possibly an essential gene, disruptants not obtained by UAU1 method || 1 0.99 0.77 0.94 1.56 0.22 0.62 0.91 1.04 0.95 1.08 0.44 0.25 0.60 0.22 0.28 0.41
854 || orf19.7537 || BNR1 || || Formin; probable role in hyphal cytoskeletal polarity; synthetic lethality if Bnr1p and Bni1p are absent || 1 0.46 0.52 0.51 0.88 0.49 0.61 0.62 0.54 0.37 0.40 0.68 -0.08 0.62 0.23 0.45 0.28
855 || orf19.6537 || || || Ortholog(s) have role in chromosome segregation and nuclear MIS12/MIND complex, spindle pole localization || 1 0.94 0.52 1.30 1.69 0.77 1.24 1.03 1.21 0.92 -0.09 1.23 0.66 1.21 0.62 1.01 0.70
856 || orf19.4544 || || || Ortholog of C. dubliniensis CD36 : Cd36_01640, C. parapsilosis CDC317 : CPAR2_106830, Candida tenuis NRRL Y-1498 : cten_CGOB_00039 and Debaryomyces hansenii CBS767 : DEHA2B06578g || 1 1.41 1.29 2.16 1.51 1.49 0.99 1.43 1.52 1.08 0.34 1.85 0.68 1.56 0.93 1.30 0.62
857 || orf19.5178 || ERG5 || || Putative C-22 sterol desaturase; fungal C-22 sterol desaturases are cytochrome P450 enzymes of ergosterol biosynthesis, catalyze formation of the C-22(23) double bond in the sterol side chain; transposon mutation affects filamentous growth || 1 1.07 0.90 1.89 1.45 0.87 0.97 1.25 1.31 1.25 0.09 1.42 0.24 1.00 0.04 0.73 0.61
858 || orf19.149 || || || Protein of unknown function; transcript detected on high-resolution tiling arrays || 1 0.82 0.78 1.15 0.97 0.73 0.71 0.62 0.98 0.62 0.49 0.37 0.19 0.42 0.17 1.11 0.48
859 || orf19.5221 || || || Ortholog(s) have phosphatidylinositol-4,5-bisphosphate binding activity || 1 0.54 0.34 0.72 0.69 0.23 0.33 0.33 0.81 0.68 0.25 0.06 0.83 0.14 0.42 0.48 0.78
860 || orf19.3980 || || || Ortholog(s) have role in cytoplasmic translation, regulation of translation and cytosol, polysomal ribosome localization || 1 0.46 0.49 0.64 0.65 0.37 0.30 0.20 0.36 0.62 0.18 0.28 0.52 0.05 0.25 0.49 0.59
861 || orf19.7074 || || || Ortholog(s) have RNA polymerase II transcription factor recruiting transcription factor activity, methylated histone residue binding activity || 1 0.47 0.49 0.91 1.06 0.41 0.50 0.23 0.58 0.63 0.16 0.21 0.90 0.22 0.48 0.40 0.71
862 || orf19.6528 || || || Ortholog of C. dubliniensis CD36 : Cd36_71740, C. parapsilosis CDC317 : CPAR2_703440, Candida tenuis NRRL Y-1498 : CANTEDRAFT_102923 and Debaryomyces hansenii CBS767 : DEHA2C03190g || 1 0.49 0.48 0.94 0.95 0.66 0.60 0.29 0.37 0.64 0.47 0.31 0.84 0.52 0.63 0.55 0.94
863 || orf19.1848.1 || || || Ortholog of S. cerevisiae : KSH1, C. dubliniensis CD36 : Cd36_32390, C. parapsilosis CDC317 : CPAR2_203260, Candida tenuis NRRL Y-1498 : CANTEDRAFT_116778 and Debaryomyces hansenii CBS767 : DEHA2A10604g || 1 0.56 0.55 0.71 0.59 0.39 0.34 0.09 0.27 0.19 0.03 0.41 0.48 0.29 0.39 0.29 0.28
864 || orf19.3543 || || || Dubious open reading frame || 1 1.41 1.03 1.18 1.49 0.66 0.92 -0.01 1.00 0.82 -0.24 0.70 0.85 0.27 0.45 0.39 1.12
865 || orf19.6488 || || || Ortholog of C. dubliniensis CD36 : Cd36_72050, C. parapsilosis CDC317 : CPAR2_301140, Candida tenuis NRRL Y-1498 : CANTEDRAFT_135055 and Debaryomyces hansenii CBS767 : DEHA2E07678g || 1 0.39 0.61 1.29 1.67 0.66 1.38 0.41 0.86 0.67 0.05 0.23 0.76 0.31 0.54 0.69 0.80
866 || orf19.4151 || SPO1 || || Protein similar to phospholipase B; fungal-specific (no human or murine homolog) || 1 0.34 0.40 1.32 1.12 0.32 0.87 0.48 0.45 0.21 0.08 0.13 0.95 0.40 0.09 0.45 0.35
867 || orf19.1548 || || || Ortholog(s) have role in mRNA splicing, via spliceosome and U4/U6 x U5 tri-snRNP complex localization || 1 1.08 0.49 1.64 1.68 0.75 1.09 0.17 0.12 0.74 0.34 0.96 0.36 1.03 0.60 0.31 0.73
868 || orf19.596.2 || DAD4 || || Subunit of the Dam1 (DASH) complex, which acts in chromosome segregation by coupling kinetochores to spindle microtubules || 1 0.41 0.48 1.02 1.07 0.08 0.68 0.48 0.61 0.70 0.26 0.51 0.63 0.70 0.39 0.02 0.63
869 || orf19.4330 || || || Ortholog of C. dubliniensis CD36 : Cd36_52790, Candida tropicalis MYA-3404 : CTRG_05968 and Candida albicans WO-1 : CAWG_04684 || 1 0.65 0.69 1.45 1.67 0.31 1.42 0.64 0.63 1.51 0.45 0.61 0.72 0.77 0.77 0.54 0.52
870 || orf19.4101 || || || Ortholog of C. parapsilosis CDC317 : CPAR2_104840, Candida tenuis NRRL Y-1498 : CANTEDRAFT_116070, Debaryomyces hansenii CBS767 : DEHA2F04994g and Pichia stipitis Pignal : psti_CGOB_00085 || 1 0.77 0.76 1.04 1.79 0.44 1.09 0.72 0.15 1.12 0.75 0.29 0.71 0.93 0.77 0.30 0.61
871 || orf19.5488 || || || Ortholog(s) have mitochondrion localization || 1 0.54 0.13 1.20 1.77 0.54 0.67 0.44 0.35 0.94 0.32 0.26 0.80 0.95 0.59 -0.35 0.38
872 || orf19.1953 || || || Predicted protein of unknown function; merged with orf19.1952 in Assembly 21 || 1 0.82 0.30 1.26 1.05 0.73 0.91 0.37 0.47 0.21 -0.18 0.29 0.25 0.37 0.21 0.70 0.03
873 || orf19.7366 || || || Ortholog(s) have S-adenosylmethionine-dependent methyltransferase activity and nucleolus localization || 1 0.74 0.52 0.86 0.72 0.56 0.69 0.19 0.66 0.11 0.22 0.19 0.23 0.21 0.36 0.37 0.02
874 || orf19.1762 || OCA1 || || Putative protein phosphatase of the PTP family (tyrosine-specific); ortholog of S. cerevisiae Oca1; mutant is viable; mutant shows virulence defect || 1 1.10 0.98 1.14 1.21 0.90 0.81 0.66 0.27 0.90 0.85 0.45 0.35 0.43 -0.09 0.75 0.04
875 || orf19.414 || RSM22 || || Predicted mitochondrial small ribosomal subunit; rat catheter and Spider biofilm induced || 1 1.15 0.86 1.29 1.19 0.89 1.32 0.21 0.49 0.34 1.09 0.06 0.26 0.53 0.06 0.47 -0.11
876 || orf19.1250 || || || Ortholog(s) have role in maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) and cytoplasm, nucleolus localization || 1 1.12 1.02 1.04 1.23 0.97 1.36 0.22 0.56 -0.14 0.45 0.29 -0.01 0.31 -0.05 0.44 0.44
877 || orf19.1335 || || || Ortholog of S. cerevisiae Mtr4, an ATP-dependent 3'-5' RNA helicase of the DEAD-box family; Hap43-induced gene; Spider biofilm induced || 1 0.74 0.76 1.03 0.82 0.69 0.94 0.27 0.16 -0.13 0.45 0.53 0.13 0.49 0.27 0.26 0.28
878 || orf19.3431 || || || Ortholog(s) have 3'-5' exonuclease activity, DNA-directed DNA polymerase activity, role in mitochondrial DNA replication and mitochondrion localization || 1 0.69 1.04 1.16 0.97 0.77 0.83 0.50 0.54 0.22 0.69 0.32 0.50 0.63 -0.07 0.23 0.52
879 || orf19.332 || || || Member of a complex that contains Prp19; stabilizes U6 snRNA in catalytic forms of the spliceosome containing U2, U5, and U6 snRNAs; Spider biofilm induced || 1 0.74 0.81 0.94 0.66 0.76 1.13 0.19 0.15 0.45 0.15 0.14 -0.00 0.49 0.30 0.09 0.43
880 || orf19.304 || || || Putative transporter similar to MDR proteins; fungal-specific; Spider biofilm induced || 1 0.89 0.85 1.16 1.10 0.76 0.78 0.10 0.18 0.64 0.39 0.20 0.18 0.35 -0.46 0.17 0.51
881 || orf19.542.2 || MIM1 || || Predicted mitochondrial protein involved in outer membrane protein import; rat catheter biofilm repressed || 1 0.89 0.59 0.94 0.75 0.57 0.66 0.19 0.30 0.50 0.28 0.22 0.21 0.32 -0.35 0.26 0.43
882 || orf19.7422 || || || Ortholog(s) have RNA binding activity and nucleus localization || 1 1.12 0.87 1.47 1.36 1.05 1.23 0.08 0.09 0.69 0.75 0.36 -0.34 1.12 0.17 1.03 0.82
883 || orf19.3455 || || || Putative mitochondrial inner membrane magnesium transporter; possibly an essential gene, disruptants not obtained by UAU1 method || 1 0.35 0.15 0.79 0.64 0.56 0.55 0.13 0.48 0.40 0.12 -0.08 0.14 0.28 0.33 0.25 0.23
884 || orf19.4266 || SPR28 || || Septin; similar to S. cerevisiae meiotic/sporulation septin; mutant has no obvious phenotype; two introns with noncanonical branch site and 5' splice site, respectively; splicing inhibited upon exposure to alpha-factor || 1 0.54 0.41 1.07 1.19 1.03 1.47 0.42 0.60 0.71 0.13 0.11 0.58 0.31 0.01 0.25 0.25
885 || orf19.4691 || MRV1 || || Ortholog of Candida albicans WO-1 : CAWG_03682 || 1 2.08 0.57 3.16 2.28 1.08 1.60 0.22 0.73 2.34 0.35 0.10 0.37 0.26 0.50 0.52 -0.03
886 || orf19.94 || || || Protein of unknown function; Spider biofilm induced || 1 1.32 0.81 1.72 1.85 0.81 1.39 0.60 0.45 0.84 0.25 0.32 -0.42 0.32 -0.25 0.85 -0.80
887 || orf19.2185 || NSA1 || || Putative 66S pre-ribosomal particles conmponent; Hap43-induced; repressed by prostaglandins || 1 1.08 0.98 1.63 1.18 1.04 1.16 0.45 0.52 0.65 0.68 0.22 -0.38 0.72 -0.45 0.34 -0.01
888 || orf19.5628 || || || Mitochondrial dicarboxylate transporter; possibly an essential gene, disruptants not obtained by UAU1 method || 1 0.98 1.09 1.12 0.94 0.84 0.97 0.30 0.69 0.14 0.04 -0.01 -0.39 0.55 -0.18 0.08 -0.19
889 || orf19.7279 || NIT2 || || Putative carbon-nitrogen hydrolase; rat catheter biofilm repressed || 1 1.48 0.99 1.22 0.93 0.84 1.51 0.42 0.50 0.73 -0.02 -0.04 -0.30 0.32 -0.05 -0.05 -0.57
890 || orf19.1915 || MPP10 || || Putative SSU processome and 90S preribosome component; repressed in core stress response; repressed by prostaglandins || 1 1.56 0.83 1.45 1.25 0.90 1.63 0.66 0.84 0.83 0.77 -0.10 -0.70 0.45 0.00 0.15 -0.38
891 || orf19.6828 || || || Ortholog(s) have role in rRNA processing and nucleolus, preribosome, large subunit precursor localization || 1 1.64 0.89 1.62 1.58 0.64 1.50 0.95 1.21 1.37 0.69 -0.08 -0.79 0.58 -0.23 0.06 -0.64
892 || orf19.4862 || || || Putative integral membrane protein; S. cerevisiae ortholog Tvp23 localizes to late Golgi vesicles; rat catheter biofilm induced || 1 0.97 0.22 1.10 1.03 0.22 0.78 0.67 0.52 0.81 -0.10 0.19 -0.37 0.34 -0.07 0.21 -0.72
893 || orf19.7111 || || || Putative mitochondrial outer membrane protein membrane fission effector; possibly an essential gene, disruptants not obtained by UAU1 method || 1 1.21 0.31 1.78 1.49 0.15 0.90 0.43 0.42 0.95 -0.12 0.41 -0.34 0.29 -0.28 0.16 -0.68
894 || orf19.1582 || || || Predicted membrane transporter; member of the drug:proton antiporter (12 spanner) (DHA1) family, major facilitator superfamily (MFS); mRNA binds She3 || 1 1.70 0.48 2.34 1.98 0.29 1.61 0.60 0.75 1.69 -0.15 0.65 -0.42 0.46 0.07 -0.06 -0.56
895 || orf19.3229 || || || Protein of unknown function; transcript detected on high-resolution tiling arrays || 1 1.24 0.38 1.07 1.11 -0.00 1.42 0.33 0.08 0.99 -0.25 0.28 -0.39 0.14 0.23 0.25 -0.19
896 || orf19.1746 || || || Protein similar to S. cerevisiae meiosis-specific, spore-wall-localized protein Ssp2p, which is required for wild-type outer spore wall formation in S. cerevisiae; possibly an essential gene (UAU1 method); Hap43p-repressed || 1 0.09 0.67 1.36 1.36 -0.07 1.17 -0.10 -0.10 0.92 -0.14 0.05 -0.16 0.33 -0.14 -0.05 -0.34
897 || orf19.4856 || LIP3 || || Secreted lipase; gene family member whose members are expressed differentially in response to carbon source and infection; possible role in nutrition and/or in creating an acidic microenvironment; flow model biofilm induced || 1 0.50 0.29 1.21 1.47 -0.22 0.43 0.22 0.32 1.02 0.09 -0.13 0.02 -0.08 -0.14 0.26 0.03
898 || orf19.6404 || GSH2 || || Putative glutathione synthase; induced in high iron; heavy metal (cadmium) stress-induced || 1 0.56 0.13 1.54 1.30 -0.13 0.43 0.23 0.09 0.46 -0.10 0.22 0.13 0.08 0.03 0.42 -0.00
899 || orf19.3969 || SFL2 || || Transcription factor involved in regulation of morphogenesis; required for filamentous growth, for virulence in RHE model but not in mice; induced upon RHE infection but C. dubliniensis ortholog is not; Spider biofilm induced || 1 0.25 0.00 1.55 1.22 -0.23 0.78 0.24 0.11 0.80 -0.12 0.13 0.15 0.07 -0.30 0.02 0.12
900 || orf19.7206 || OCA6 || || Putative protein phosphatase of the PTP family (tyrosine-specific), similar to S. cerevisiae Oca6p; mutant shows virulence defect || 1 0.00 0.10 1.05 0.86 0.03 0.44 0.20 -0.08 0.58 -0.37 0.07 0.08 -0.03 0.05 0.15 -0.07
901 || orf19.3437 || || || Has domain(s) with predicted serine-type endopeptidase activity and role in proteolysis || 1 0.38 0.59 2.16 1.29 0.66 0.15 -0.06 -0.20 0.55 -0.59 -0.48 -0.45 0.76 0.03 0.35 -0.16
902 || orf19.5915 || DUR35 || || Putative urea transporter || 1 0.18 0.62 1.94 1.32 0.27 0.54 -0.16 -0.06 0.45 -0.48 -0.62 -0.52 0.55 -0.09 -0.10 -0.03
903 || orf19.4104 || || || Ortholog of C. dubliniensis CD36 : Cd36_20540, C. parapsilosis CDC317 : CPAR2_104860, Candida tenuis NRRL Y-1498 : CANTEDRAFT_116071 and Pichia stipitis Pignal : PICST_32327 || 1 0.24 0.18 1.14 1.00 0.31 0.91 0.14 0.28 0.26 -0.49 -0.27 -0.11 0.71 -0.10 0.25 -0.04
904 || orf19.4504 || || || Has domain(s) with predicted oxidoreductase activity, transferase activity, transferring acyl groups other than amino-acyl groups, zinc ion binding activity and role in oxidation-reduction process || 1 0.27 0.39 1.41 1.56 0.28 0.67 0.04 0.12 -0.01 -0.37 -0.60 -0.28 0.61 -0.15 0.14 -0.22
905 || orf19.4691 || MRV1 || || Ortholog of Candida albicans WO-1 : CAWG_03682 || 1 0.25 0.43 1.63 1.48 1.07 0.71 -0.16 0.01 0.24 -0.10 -0.35 -0.23 0.26 -0.20 -0.05 -0.24
906 || orf19.6900 || || || Ortholog(s) have role in establishment or maintenance of cell polarity, mitochondrial genome maintenance, mitochondrion inheritance, phospholipid transport, protein import into mitochondrial outer membrane || 1 0.22 0.57 1.32 1.10 0.71 0.46 0.37 -0.20 0.46 -0.18 -0.40 0.05 0.42 0.21 0.23 0.17
907 || orf19.1162.1 || || || Ortholog(s) have Golgi apparatus localization || 1 0.71 0.74 2.47 2.43 0.65 1.20 0.62 -0.18 1.09 -0.35 -0.43 0.21 0.73 -0.19 0.55 0.08
908 || orf19.732 || || || Possible dehydrogenase; flow model biofilm induced; rat catheter biofilm induced; Spider biofilm induced || 1 0.97 0.96 2.43 2.00 0.94 1.00 1.07 -0.19 1.01 -0.41 -0.41 -0.28 0.87 -0.29 0.55 0.09
909 || orf19.4834 || || || Ortholog of C. dubliniensis CD36 : Cd36_09140, C. parapsilosis CDC317 : CPAR2_804920, Debaryomyces hansenii CBS767 : DEHA2B10516g and Pichia stipitis Pignal : PICST_30058 || 1 0.80 1.11 2.53 2.25 1.01 0.98 0.93 0.09 1.34 -0.22 0.06 -0.19 0.90 -0.08 0.34 -0.04
910 || orf19.2496 || ATO2 || || Putative fungal-specific transmembrane protein; fluconazole repressed, Hap43-repressed; flow model biofilm induced; Spider biofilm induced || 1 0.33 0.48 1.78 1.78 0.40 0.56 0.30 0.20 0.73 0.07 -0.37 -0.50 0.43 -0.38 0.34 -0.00
911 || orf19.2857 || || || Ortholog(s) have ATP-dependent DNA helicase activity || 1 0.73 0.60 2.23 2.57 0.18 1.43 0.22 0.12 1.03 -0.15 -0.60 0.03 0.18 -0.40 0.28 -0.49
912 || orf19.2264 || OLE2 || || Protein with similarity to fatty acid desaturase (stearoyl-CoA desaturase); homozygous null mutant shows decreased production of prostaglandin E2 || 1 0.48 0.27 1.55 1.79 0.23 1.18 0.09 -0.01 0.43 -0.32 -0.05 -0.23 0.23 -0.31 0.07 -0.37
913 || orf19.5231 || || || Protein of unknown function; flow model biofilm induced || 1 0.32 1.02 2.43 2.67 0.43 1.43 0.25 0.49 1.05 -0.24 0.12 -0.28 0.38 0.17 0.02 -0.53
914 || orf19.3420 || || || Protein of unknown function; decreased expression in hyphae than in yeast || 1 0.26 0.27 2.09 1.54 0.37 0.80 0.23 -0.27 0.67 -0.37 -0.19 -0.25 0.81 -0.09 -0.02 -0.12
915 || orf19.371 || || || Ortholog of C. dubliniensis CD36 : Cd36_40110, C. parapsilosis CDC317 : CPAR2_402300, Candida tenuis NRRL Y-1498 : CANTEDRAFT_94507 and Debaryomyces hansenii CBS767 : DEHA2F05588g || 1 0.34 0.61 2.12 1.73 0.23 0.62 0.35 -0.28 0.58 -0.36 -0.39 0.13 0.49 0.05 0.35 0.33
916 || orf19.115 || || || Ortholog of Candida tropicalis MYA-3404 : CTRG_02973 and Candida albicans WO-1 : CAWG_05252 || 1 0.28 0.74 2.47 1.93 0.33 0.65 0.28 -0.04 0.66 -0.15 -0.32 0.22 0.42 -0.03 0.25 0.05
917 || orf19.115 || || || Ortholog of Candida tropicalis MYA-3404 : CTRG_02973 and Candida albicans WO-1 : CAWG_05252 || 1 0.23 0.52 1.63 1.66 0.35 0.75 0.05 -0.00 0.69 0.05 -0.10 0.22 0.31 -0.17 0.01 0.10
918 || orf19.7252 || || || Ortholog of Candida albicans WO-1 : CAWG_00017 || 1 0.25 0.47 2.39 2.04 0.72 1.04 0.00 -0.17 0.76 -0.35 0.04 0.11 0.45 -0.44 0.22 -0.09
919 || orf19.10713 || PAPALPHA || || Putative poly(A) polymerase; PAP is inhibited by parnafungin antifungals; non-sex gene located within the MTLalpha mating-type-like locus || 1 0.33 0.46 2.19 1.53 0.49 0.76 0.13 0.07 0.61 -0.52 0.02 -0.04 0.37 -0.53 0.14 0.13
920 || orf19.4652 || || || Protein of unknown function; rat catheter biofilm induced || 1 0.31 0.44 1.74 1.66 0.19 0.62 -0.03 0.13 0.68 -0.26 0.04 -0.17 0.26 -0.37 -0.00 0.37
921 || orf19.3263 || ATO10 || || Putative fungal-specific transmembrane protein; rat catheter and Spider biofilm induced || 1 0.29 0.25 2.11 1.95 0.03 0.70 0.13 -0.05 0.62 -0.30 0.08 0.13 -0.08 -0.29 0.19 0.30
922 || orf19.1780 || || || Has domain(s) with predicted catalytic activity || 1 -0.04 0.33 1.91 1.48 0.18 0.71 -0.07 -0.19 0.60 -0.01 -0.19 0.38 0.08 -0.15 0.03 -0.03
923 || orf19.538 || GPI2 || || Subunit of the GPI-N-acetylglucosaminyl transferase (GPI-GnT) that catalyzes the first step in GPI anchor biosynthesis || 1 0.18 0.19 1.53 1.36 0.66 0.48 0.25 -0.13 0.42 -0.04 -0.09 -0.01 -0.00 -0.04 0.00 0.14
924 || orf19.7666 || || || Predicted membrane transporter, member of the anion:cation symporter (ACS) family, major facilitator superfamily (MFS) || 1 0.32 0.48 1.62 1.34 0.31 0.51 -0.18 -0.19 0.38 -0.38 -0.21 -0.07 0.33 -0.45 0.10 0.31
925 || orf19.6950 || || || Putative vacuolar membrane transporter for cationic amino acids; Spider biofilm induced || 1 0.37 0.45 1.70 1.21 0.33 0.54 -0.54 -0.54 0.51 -0.47 -0.17 -0.20 0.49 -0.44 -0.00 0.25
926 || orf19.1935 || || || Dubious open reading frame || 1 0.61 0.90 1.70 1.55 0.75 0.75 -0.32 -0.40 0.60 -0.27 0.30 0.15 0.82 -0.28 -0.15 0.17
927 || orf19.3440 || FRP5 || || Protein with a GPR1/FUN34/yaaH family domain; flucytosine repressed || 1 0.59 0.63 1.25 1.36 0.68 0.78 0.04 -0.01 0.62 -0.30 0.08 0.07 0.31 -0.19 0.18 0.46
928 || orf19.1780 || || || Has domain(s) with predicted catalytic activity || 1 0.81 0.48 1.51 1.28 0.74 0.82 -0.27 -0.04 0.49 -0.42 0.02 -0.01 0.53 -0.61 0.11 0.32
929 || orf19.4652 || || || Protein of unknown function; rat catheter biofilm induced || 1 0.78 0.73 1.84 1.74 0.61 0.81 -0.45 -0.11 0.81 -0.25 -0.50 -0.02 0.48 -0.51 -0.20 0.10
930 || orf19.2889 || || || Ortholog(s) have role in chromatin remodeling and Ino80 complex, cytoplasm localization || 1 0.88 0.69 1.57 1.69 0.59 1.00 -0.27 -0.21 0.48 0.17 -0.34 -0.02 0.29 -0.27 -0.05 0.17
931 || orf19.3376 || || || Ortholog of Candida albicans WO-1 : CAWG_03459 || 1 0.97 0.54 1.58 1.98 0.41 0.68 -0.38 -0.12 0.79 -0.41 0.03 -0.16 0.43 -0.23 -0.39 0.66
932 || orf19.6756 || || || Ortholog(s) have Rab GTPase binding activity and Golgi apparatus, endoplasmic reticulum localization || 1 0.12 0.34 1.12 1.04 0.29 0.14 -0.20 0.08 0.58 -0.13 -0.18 -0.16 0.23 -0.25 -0.13 -0.06
933 || orf19.138 || FIG1 || || S. cerevisiae Fig1 ortholog; an integral membrane protein required for mating; role in thigmotropism; transcript is opaque-specific and a-specific; activated by Cph1 or alpha pheromone || 1 0.27 0.11 1.01 1.22 0.32 0.40 -0.16 0.00 0.44 -0.12 -0.45 0.04 0.53 -0.34 0.03 -0.06
934 || orf19.2211 || || || Ortholog of C. dubliniensis CD36 : Cd36_21990, C. parapsilosis CDC317 : CPAR2_103660, Debaryomyces hansenii CBS767 : DEHA2F19756g and Pichia stipitis Pignal : PICST_61375 || 1 0.22 0.37 1.05 1.43 0.44 0.75 -0.14 -0.14 0.71 -0.29 -0.46 0.16 0.56 0.11 0.13 -0.45
935 || orf19.5037 || HRQ2 || || Protein of unknown function; mutants are viable; rat catheter and Spider biofilm induced || 1 0.65 1.07 1.25 2.47 0.86 0.95 -0.15 -0.27 1.03 -0.36 -0.51 0.12 0.86 -0.46 0.33 -0.45
936 || orf19.2186 || SEH1 || || Ortholog(s) have Seh1-associated complex, cytosol, fungal-type vacuole membrane, nuclear membrane, nuclear pore outer ring localization || 1 0.10 0.31 0.53 0.92 0.29 0.19 0.05 -0.01 0.58 -0.28 -0.22 0.11 0.30 -0.09 -0.05 -0.04
937 || orf19.3735 || || || Protein of unknown function; induced by alpha pheromone in SpiderM medium || 1 0.19 0.26 1.08 0.97 -0.04 0.35 -0.10 0.25 0.33 -0.14 -0.16 0.23 0.38 0.10 -0.14 0.23
938 || orf19.2925 || || || Ortholog(s) have role in protein folding, tubulin complex assembly and cytoplasm localization || 1 0.27 0.30 1.48 1.10 0.06 0.64 0.21 0.05 0.48 -0.03 -0.23 0.59 0.19 0.54 -0.04 0.29
939 || orf19.3111 || PRA1 || || Cell surface protein that sequesters zinc from host tissue; enriched at hyphal tips; released extracellularly; binds to host complement regulators; mediates leukocyte adhesion and migration; immunogenic in mouse; produced at ambient pH || 1 0.22 0.28 0.85 1.05 0.14 0.92 -0.02 0.02 0.72 0.08 0.28 0.41 0.07 0.29 0.05 -0.01
940 || orf19.7103 || || || Predicted exonuclease; Spider biofilm induced || 1 0.15 0.36 1.02 0.99 0.27 0.89 -0.16 0.01 0.71 -0.06 0.22 0.45 0.02 0.58 0.08 0.37
941 || orf19.1456 || || || Ortholog of Candida albicans WO-1 : CAWG_03922 || 1 0.31 0.83 1.85 1.77 0.75 1.39 -0.07 0.37 1.40 -0.11 0.07 0.51 -0.03 0.02 0.30 0.51
942 || orf19.2366 || || || Has domain(s) with predicted DNA binding activity and role in DNA integration || 1 0.48 0.71 1.64 1.50 0.62 0.93 -0.18 0.15 1.11 0.15 -0.12 0.50 0.09 0.11 0.10 0.39
943 || orf19.5231 || || || Protein of unknown function; flow model biofilm induced || 1 0.64 0.58 1.81 1.99 0.37 1.24 -0.18 0.10 1.05 -0.02 -0.07 0.65 0.18 0.45 0.24 0.68
944 || orf19.5588 || PGA60 || || Putative GPI-anchored adhesin-like protein; hyphal-induced expression || 1 0.79 0.81 1.67 1.59 0.16 0.97 0.15 0.29 1.10 -0.10 0.10 0.28 0.27 0.24 0.08 0.25
945 || orf19.3905 || MRV5 || || Planktonic growth-induced gene || 1 0.51 0.60 1.65 1.16 0.44 1.18 -0.16 0.26 0.82 -0.43 0.12 0.92 0.09 -0.25 -0.18 0.12
946 || orf19.7063 || THG1 || || tRNA guanylyltransferase, with role in tRNA modification; catalyzes reverse (3'-5') nucleotide polymerization || 1 0.00 0.24 1.01 0.82 0.12 0.75 -0.24 -0.17 0.37 0.08 -0.18 0.34 0.08 0.11 -0.24 -0.47
947 || orf19.598 || || || Ortholog of Candida albicans WO-1 : CAWG_02092 || 1 0.29 0.32 1.46 1.42 0.18 1.16 -0.29 -0.50 0.74 -0.33 -0.16 0.36 -0.02 0.30 -0.27 -0.08
948 || orf19.1547 || || || Ortholog(s) have double-stranded DNA binding, polynucleotide 3'-phosphatase activity and role in double-strand break repair || 1 0.15 0.38 1.28 0.88 0.20 0.62 -0.28 -0.19 0.61 -0.05 -0.13 0.52 0.29 0.49 -0.10 -0.10
949 || orf19.4964 || || || Ortholog(s) have role in cellular bud site selection, mRNA export from nucleus, mRNA splicing, via spliceosome and RES complex localization || 1 -0.04 0.30 1.98 1.72 0.38 0.89 -0.21 -0.10 0.89 0.17 -0.26 0.19 0.43 0.31 -0.15 -0.21
950 || orf19.3604 || || || Ortholog(s) have nucleus localization || 1 0.12 0.21 1.52 1.36 0.09 0.82 0.00 0.11 0.81 0.11 -0.52 -0.11 0.05 0.24 -0.09 -0.29
951 || orf19.2103 || || || Ortholog of Candida albicans WO-1 : CAWG_03811 || 1 0.17 0.23 1.52 1.06 0.06 0.71 -0.39 -0.34 0.62 0.20 -0.19 0.13 0.09 0.14 -0.17 0.34
952 || orf19.3455 || || || Putative mitochondrial inner membrane magnesium transporter; possibly an essential gene, disruptants not obtained by UAU1 method || 1 0.17 0.08 1.02 0.94 0.35 0.59 -0.17 -0.22 0.56 0.04 -0.27 0.14 0.48 0.13 -0.26 0.19
953 || orf19.4330 || || || Ortholog of C. dubliniensis CD36 : Cd36_52790, Candida tropicalis MYA-3404 : CTRG_05968 and Candida albicans WO-1 : CAWG_04684 || 1 -0.28 -0.01 1.02 0.88 0.15 0.55 -0.22 -0.34 0.44 0.08 -0.30 0.09 0.27 -0.01 -0.29 -0.02
954 || orf19.6184 || || || Protein of unknown function; Spider biofilm repressed || 1 0.18 0.67 1.47 0.89 0.81 0.21 -0.33 -0.26 0.62 -0.40 -0.43 0.11 0.84 -0.30 0.03 0.27
955 || orf19.3887 || || || Ortholog(s) have cytoplasm, nucleus localization || 1 0.30 0.61 2.03 1.25 0.57 0.69 -0.34 -0.43 0.47 -0.34 -0.43 0.38 0.74 -0.00 0.37 0.26
956 || orf19.2663 || || || Ortholog of Pichia stipitis Pignal : PICST_29216 and Candida albicans WO-1 : CAWG_00788 || 1 0.27 0.20 0.63 0.34 0.29 0.16 -0.15 -0.10 0.15 0.06 -0.04 -0.01 0.37 -0.03 0.06 0.25
957 || orf19.3109 || || || Ortholog of C. dubliniensis CD36 : Cd36_46470, C. parapsilosis CDC317 : CPAR2_500900, Debaryomyces hansenii CBS767 : DEHA2B15730g and Candida tropicalis MYA-3404 : CTRG_03755 || 1 0.76 0.78 1.97 1.76 0.78 0.20 -0.26 -0.05 0.53 -0.09 0.32 -0.13 0.98 -0.12 0.25 0.46
958 || orf19.2285 || || || Protein of unknown function; transcription induced by benomyl treatment || 1 0.51 0.93 1.30 1.40 0.04 0.56 0.02 0.01 1.47 0.21 0.17 -0.16 0.18 0.47 0.03 0.64
959 || orf19.1365 || || || Putative monooxygenase; mutation confers hypersensitivity to toxic ergosterol analog; constitutive expression independent of MTL or white-opaque status || 1 1.01 1.00 1.84 2.08 0.18 0.63 0.37 0.26 1.17 -0.20 -0.28 -0.04 0.27 0.39 -0.25 0.65
960 || orf19.4567 || || || Catechol 1,2-dioxygenase (1,2-CTD), involved in degradation of aromatic compounds; Spider biofilm induced || 1 0.33 0.49 0.94 1.33 0.25 0.62 0.35 0.26 0.91 0.41 -0.46 -0.12 0.50 0.58 -0.02 -0.14
961 || orf19.944 || IFG3 || || Putative D-amino acid oxidase; Spider biofilm induced || 1 0.66 0.46 0.84 1.12 0.11 0.23 0.52 0.19 0.84 0.20 -0.19 -0.19 0.21 0.36 0.18 -0.01
962 || orf19.5741 || ALS1 || || Cell-surface adhesin; adhesion, virulence, immunoprotective roles; band at hyphal base; Rfg1, Ssk1, Spider biofilm induced; flow model biofilm repressed; CAI-4 strain background effects; promoter bound Bcr1, Tec1, Efg1, Ndt80, and Brg1 || 1 0.64 0.53 1.26 1.59 -0.03 0.89 0.80 0.54 1.07 0.01 -0.43 -0.49 0.80 0.26 0.18 0.27
963 || orf19.5169 || || || Ortholog(s) have cytosol, nucleus localization || 1 0.89 0.56 1.52 1.65 -0.28 0.46 0.83 0.50 0.85 -0.16 -0.57 -0.50 0.41 0.25 -0.17 -0.10
964 || orf19.5270 || || || Protein of unknown function; rat catheter biofilm induced || 1 1.20 1.21 1.52 1.36 0.00 0.44 0.59 0.49 0.81 0.25 -0.78 -0.52 0.63 0.01 0.40 -0.05
965 || orf19.1748 || || || Protein of unknown function; shows colony morphology-related gene regulation by Ssn6 || 1 0.35 0.46 0.89 0.92 0.17 0.27 0.16 0.31 0.31 -0.21 -0.34 0.16 0.26 -0.52 0.36 0.41
966 || orf19.6591 || PCD1 || || Ortholog(s) have 8-oxo-7,8-dihydroguanosine triphosphate pyrophosphatase activity, role in DNA repair and peroxisome localization || 1 0.25 0.50 0.82 1.17 0.16 0.26 0.30 0.17 0.02 -0.27 -0.15 0.10 0.20 -0.04 0.41 0.33
967 || orf19.7364 || || || Has domain(s) with predicted N,N-dimethylaniline monooxygenase activity, NADP binding, flavin adenine dinucleotide binding activity and role in oxidation-reduction process || 1 0.34 0.35 0.94 1.36 0.22 0.39 -0.06 -0.24 0.56 -0.30 -0.17 0.03 0.23 0.12 0.14 0.73
968 || orf19.2581 || || || Protein with a predicted epimerase/dehydratase domain; Hap43-repressed gene || 1 0.58 0.09 1.57 2.28 0.33 0.86 0.13 -0.34 0.72 -0.56 0.11 0.22 0.62 -0.09 0.47 0.92
969 || orf19.1107 || || || Protein of unknown function; Spider biofilm induced || 1 0.33 0.32 0.60 0.98 0.26 0.51 0.06 0.08 0.44 -0.34 0.23 0.36 0.32 -0.09 0.25 0.25
970 || orf19.4550 || || || Predicted MFS membrane transporter, member of the drug:proton antiporter (12 spanner) (DHA1) family; flow model biofilm induced || 1 0.42 0.25 0.83 0.91 0.42 0.21 -0.04 0.06 0.34 -0.41 0.03 0.25 0.42 -0.18 0.22 0.47
971 || orf19.3362 || || || Has domain(s) with predicted flavin adenine dinucleotide binding, oxidoreductase activity and role in oxidation-reduction process || 1 0.90 0.60 1.15 1.14 0.53 0.46 0.11 0.09 0.47 -0.75 0.29 0.08 0.63 0.01 0.61 0.63
972 || orf19.6131 || KSR1 || || 3-ketosphinganine reductase, catalyzes the second step in phytosphingosine synthesis || 1 1.30 0.86 1.86 2.27 0.57 0.95 -0.40 -0.32 0.79 -0.43 0.01 0.12 0.75 -0.48 0.93 0.71
973 || orf19.1637 || || || Ortholog(s) have cytosol, nucleus localization || 1 0.72 0.39 0.93 1.10 0.25 0.42 -0.33 -0.22 0.51 -0.19 -0.28 0.06 0.34 -0.08 0.64 0.33
974 || orf19.5270 || || || Protein of unknown function; rat catheter biofilm induced || 1 0.53 0.30 1.11 0.90 0.28 0.12 0.01 0.13 0.32 0.08 -0.34 -0.19 0.18 -0.05 0.33 0.26
975 || orf19.3828 || || || Ortholog of Candida albicans WO-1 : CAWG_03357 || 1 0.44 0.63 1.21 1.12 0.37 0.47 0.26 0.12 0.71 0.24 -0.39 0.30 0.18 -0.38 0.46 0.04
976 || orf19.2808 || ZCF16 || || Predicted Zn(II)2Cys6 transcription factor; mutants are viable; rat catheter biofilm induced || 1 0.49 0.38 0.80 0.81 0.35 0.34 0.17 0.13 0.49 0.25 -0.55 0.17 0.22 -0.29 0.56 -0.03
977 || orf19.2400 || || || Ortholog(s) have role in mRNA splicing, via spliceosome, maturation of SSU-rRNA, positive regulation of ATPase activity, positive regulation of helicase activity || 1 0.86 0.72 0.88 0.89 1.04 0.41 0.42 0.54 0.69 -0.12 0.08 0.44 -0.21 0.13 0.43 0.55
978 || orf19.6063 || UBP6 || || Putative ubiquitin-specific protease of the 26S proteasome; oxidative stress-induced via Cap1p || 1 0.66 0.42 0.73 1.05 0.42 0.30 0.24 0.50 0.06 0.14 0.10 0.36 0.29 0.20 0.69 0.57
979 || orf19.2926 || || || Putative nuclease required for DNA single- and double-strand break repair; rat catheter biofilm induced || 1 0.47 0.35 0.80 0.57 0.27 0.40 0.22 0.09 0.28 0.12 -0.14 0.34 0.19 0.23 0.21 0.47
980 || orf19.2072 || || || Ortholog(s) have (R)-carnitine transmembrane transporter activity, choline transmembrane transporter activity, ethanolamine transmembrane transporter activity || 1 0.86 0.26 1.10 1.34 0.60 1.11 0.41 0.46 0.43 0.15 -0.35 0.45 -0.09 -0.04 0.48 0.66
981 || orf19.5353 || || || Ortholog of C. parapsilosis CDC317 : CPAR2_407790, C. dubliniensis CD36 : Cd36_24630, Candida orthopsilosis Co 90-125 : CORT_0C07130 and Spathaspora passalidarum NRRL Y-27907 : SPAPADRAFT_149801 || 1 0.76 0.25 0.88 0.71 0.65 0.51 0.12 0.36 -0.05 0.39 -0.14 0.41 0.00 0.20 0.37 0.20
982 || orf19.515 || || || Has domain(s) with predicted nucleic acid binding, zinc ion binding activity || 1 1.35 0.24 1.35 1.18 0.83 1.79 0.43 0.23 0.91 0.05 0.40 -0.09 0.43 0.17 0.71 0.21
983 || orf19.6470 || AHP2 || || Putative thiol-specific peroxiredoxin; macrophage-downregulated gene || 1 0.39 0.14 0.98 1.14 0.56 1.53 0.43 0.22 1.34 -0.47 0.41 0.39 0.12 -0.28 0.62 0.33
984 || orf19.6555 || || || Ortholog(s) have zinc ion binding activity, role in protein import into mitochondrial intermembrane space and cytosol, mitochondrial intermembrane space, nucleus localization || 1 0.76 0.26 1.20 1.74 0.87 1.52 0.85 0.27 0.70 -0.50 0.64 0.47 0.79 -0.25 0.91 1.03
985 || orf19.6544 || LPI9 || || Protein phosphatase type 1 regulator; role in chromosome segregation, regulation of phosphoprotein phosphatase activity; rat catheter and Spider biofilm induced || 1 0.88 0.64 0.68 1.37 0.99 0.82 0.22 0.17 1.04 -0.12 -0.02 0.64 0.47 0.20 1.00 0.56
986 || orf19.3998 || || || Ortholog(s) have Atg8 ligase activity, protein binding, bridging activity and role in C-terminal protein lipidation, CVT pathway, macroautophagy, mitochondrion degradation, piecemeal microautophagy of nucleus || 1 0.78 0.88 0.92 1.18 0.98 1.24 -0.17 0.25 0.67 0.57 0.60 0.21 0.65 0.73 0.17 1.35
987 || orf19.5045 || PTP2 || || Predicted protein tyrosine phosphatase; involved in regulation of MAP kinase Hog1 activity; induced by Mnl1 under weak acid stress; rat catheter and Spider biofilm induced || 1 0.98 1.06 1.00 0.99 1.20 0.73 -0.05 -0.13 1.09 -0.16 0.80 0.03 0.82 0.64 0.78 1.27
988 || orf19.5045 || PTP2 || || Predicted protein tyrosine phosphatase; involved in regulation of MAP kinase Hog1 activity; induced by Mnl1 under weak acid stress; rat catheter and Spider biofilm induced || 1 0.79 1.02 1.30 1.34 1.10 1.31 -0.12 -0.05 1.45 -0.19 0.84 -0.06 0.80 0.74 0.62 1.26
989 || orf19.5961 || || || Ortholog(s) have role in proteasome regulatory particle assembly, proteolysis and cytosol, nucleus, proteasome regulatory particle localization || 1 1.12 1.12 1.94 1.14 1.48 1.70 -0.24 -0.20 0.77 -0.37 0.29 -0.06 0.82 0.22 0.97 1.20
990 || orf19.2826 || || || Ortholog of C. dubliniensis CD36 : Cd36_27680, C. parapsilosis CDC317 : CPAR2_801140, Candida tenuis NRRL Y-1498 : CANTEDRAFT_129982 and Debaryomyces hansenii CBS767 : DEHA2E09526g || 1 0.25 0.68 0.99 0.47 0.72 0.94 0.24 0.10 0.67 -0.28 0.36 -0.01 0.93 0.14 0.19 0.75
991 || orf19.6118 || || || Putative guanine nucleotide dissociation stimulator; transcription is positively regulated by Tbf1p || 1 0.71 0.94 0.73 0.58 1.04 1.20 -0.07 -0.07 0.77 -0.29 0.83 0.67 0.93 0.06 0.22 0.82
992 || orf19.1191 || || || Ortholog(s) have ubiquitin-protein ligase activity and role in ER-associated ubiquitin-dependent protein catabolic process || 1 0.21 0.22 0.46 0.24 0.54 0.37 -0.04 -0.01 0.34 0.01 0.14 0.38 0.21 0.05 0.38 0.56
993 || orf19.6020 || || || Ortholog(s) have Atg8 ligase activity and role in C-terminal protein lipidation, CVT pathway, autophagic vacuole assembly, cellular response to nitrogen starvation, mitochondrion degradation, piecemeal microautophagy of nucleus || 1 1.24 0.70 1.45 0.88 1.17 1.44 0.07 0.19 0.29 0.09 0.58 0.52 0.03 -0.13 1.51 0.29
994 || orf19.4292 || || || Ortholog(s) have SNAP receptor activity, role in Golgi to vacuole transport, vacuole inheritance and Golgi apparatus, endosome localization || 1 0.70 0.58 0.76 0.70 0.65 0.76 0.09 0.08 0.08 0.09 0.25 0.10 -0.20 -0.01 0.58 0.38
995 || orf19.2089 || || || Ortholog of Nyv1, v-SNARE component of the vacuolar SNARE complex involved in vesicle fusion in S. cerevisiae; Hap43-repressed gene || 1 0.44 0.40 0.61 0.40 0.40 0.61 0.15 0.07 0.00 -0.23 0.24 0.22 -0.05 -0.08 0.44 0.44
996 || orf19.3077 || VID21 || || Subunit of the NuA4 histone acetyltransferase complex; soluble protein in hyphae; Spider biofilm repressed || 1 0.39 0.35 0.93 0.82 0.68 0.99 0.32 0.26 0.17 -0.06 0.42 0.16 0.23 0.19 0.70 0.62
997 || orf19.3848 || || || Ortholog of C. dubliniensis CD36 : Cd36_31420, C. parapsilosis CDC317 : CPAR2_205100, Debaryomyces hansenii CBS767 : DEHA2G10648g and Pichia stipitis Pignal : PICST_32997 || 1 0.56 0.46 1.23 1.18 0.95 0.91 -0.01 0.14 0.23 0.41 0.08 0.47 0.28 0.42 1.09 0.88
998 || orf19.6811 || ISA2 || || Protein required for maturation of mitochondrial [4Fe-4S] proteins; role in biotin biosynthetic process; rat catheter and Spider biofilm induced || 1 0.32 0.55 0.69 0.73 0.47 0.57 -0.08 0.16 0.38 0.09 0.11 0.26 0.09 0.14 0.62 0.43
999 || orf19.5974 || ATG9 || || Protein similar to S. cerevisiae Atg9; required for early step in autophagy; required for cytoplasm to vacuole trafficking of Lap41; Spider biofilm induced || 1 0.58 0.71 1.00 0.69 0.91 0.80 0.28 0.43 0.22 0.13 0.04 0.68 0.34 0.23 0.60 0.49
1000 || orf19.3999 || || || Ortholog(s) have fungal-type vacuole membrane localization || 1 0.53 0.62 0.93 0.84 0.95 0.85 -0.04 0.01 0.62 0.17 0.22 0.70 -0.02 0.12 0.44 0.15
1001 || orf19.6444 || || || Ortholog(s) have role in cellular response to amino acid starvation, meiosis, negative regulation of TOR signaling cascade, regulation of autophagic vacuole assembly || 1 0.61 0.59 0.57 0.47 1.40 0.96 -0.05 0.14 0.52 0.13 0.50 0.42 0.08 0.28 0.67 0.37
1002 || orf19.1519 || || || Protein of unknown function; Hap43-repressed gene || 1 0.58 0.47 0.49 0.42 0.91 0.55 0.09 0.46 0.67 0.07 0.25 0.54 0.19 -0.01 0.56 0.52
1003 || orf19.537 || || || Ortholog of C. dubliniensis CD36 : Cd36_29810, C. parapsilosis CDC317 : CPAR2_206030, Candida tenuis NRRL Y-1498 : CANTEDRAFT_102086 and Debaryomyces hansenii CBS767 : DEHA2F14014g || 1 0.67 0.62 1.26 0.79 0.72 1.19 0.04 0.32 0.69 0.51 0.52 0.81 0.62 -0.22 0.53 0.91
1004 || orf19.7598 || || || Ortholog(s) have histone acetyltransferase activity, role in histone acetylation and Ada2/Gcn5/Ada3 transcription activator complex localization || 1 0.40 0.32 1.06 0.84 0.81 1.09 0.04 0.06 0.31 -0.07 0.75 0.64 0.48 -0.12 0.48 0.45
1005 || orf19.308 || || || Ortholog(s) have role in nucleobase-containing compound transport and plasma membrane localization || 1 0.11 0.45 0.94 0.71 0.38 1.17 -0.05 -0.01 0.37 -0.14 0.73 0.67 0.27 -0.18 0.40 0.39
1006 || orf19.5574 || || || Ortholog(s) have mitochondrial outer membrane localization || 1 0.17 0.17 0.81 0.75 0.17 0.58 0.15 0.22 0.36 0.03 0.55 0.15 0.26 0.16 -0.04 -0.12
1007 || orf19.2518 || || || Ortholog(s) have ATPase activator activity, soluble NSF attachment protein activity || 1 0.19 0.04 1.08 0.98 0.29 0.82 0.45 0.20 0.66 -0.12 0.61 0.07 0.06 -0.01 0.19 -0.19
1008 || orf19.4183 || MUC1 || || Protein similar to S. cerevisiae Muc1; a cell surface glycoprotein involved in filamentous growth; repressed by benomyl treatment; mutant is viable || 1 0.26 0.41 0.84 0.91 0.09 0.60 0.32 0.04 0.64 -0.21 0.29 0.22 0.46 -0.32 0.32 -0.29
1009 || orf19.1953 || || || Predicted protein of unknown function; merged with orf19.1952 in Assembly 21 || 1 0.10 0.40 0.14 0.62 0.42 0.32 0.04 0.14 0.51 0.03 0.10 0.19 0.41 0.01 0.45 -0.26
1010 || orf19.6790 || || || Ortholog(s) have mRNA binding activity, role in 3'-UTR-mediated mRNA destabilization, mitochondrion organization and cytoplasmic mRNA processing body, cytoplasmic stress granule, cytosol, perinuclear region of cytoplasm localization || 1 0.16 0.95 0.82 0.75 0.61 0.73 0.21 0.20 0.57 0.01 -0.03 0.20 0.56 0.15 0.83 -0.44
1011 || orf19.723 || BCR1 || || Transcription factor; regulates a/alpha biofilm formation, matrix, cell-surface-associated genes; confers adherence, impermeability, impenetrability, fluconazole resistance; Tup1/Tec1/Mnl1-regulated; mRNA binds She3; Spider biofilm induced || 1 0.67 0.74 1.00 1.00 0.56 0.28 0.50 0.16 0.54 0.54 -0.03 0.24 1.00 0.16 0.92 -0.15
1012 || orf19.2695 || UBR1 || || Protein similar to S. cerevisiae Ubr1p ubiquitin-protein ligase; transposon mutation affects filamentous growth; Spider biofilm induced || 1 0.51 0.38 0.38 0.40 0.34 0.44 0.26 0.27 0.46 0.26 -0.17 0.07 0.31 -0.03 0.44 -0.03
1013 || orf19.2173 || MAF1 || || Putative negative regulator of RNA polymerase III; decreased expression in hyphae vs yeast cells; caspofungin repressed; Spider biofilm repressed || 1 1.67 0.76 1.54 1.28 0.99 1.55 0.49 0.72 0.95 -0.53 0.16 -0.20 0.32 -1.03 0.73 0.38
1014 || orf19.6900 || || || Ortholog(s) have role in establishment or maintenance of cell polarity, mitochondrial genome maintenance, mitochondrion inheritance, phospholipid transport, protein import into mitochondrial outer membrane || 1 0.77 0.63 0.56 0.83 0.41 0.32 0.11 0.31 0.55 -0.32 0.14 -0.03 0.41 -0.19 0.57 0.47
1015 || orf19.1981 || IMP2 || || Predicted subunit of the mitochondrial inner membrane peptidase complex involved in protein targeting to mitochondria || 1 -0.21 -0.02 1.26 1.03 0.34 0.78 0.04 -0.04 0.12 0.03 0.18 0.32 0.24 -0.04 0.22 0.03
1016 || orf19.3638 || PGA46 || || Putative GPI-anchored protein; secreted; fluconazole-induced || 1 0.07 -0.12 1.78 0.90 0.43 1.02 0.00 0.03 0.32 -0.17 0.78 0.73 0.10 0.38 0.43 0.56
1017 || orf19.6016 || || || Ortholog(s) have GTPase activity, calcium ion binding activity, role in mitochondrion inheritance, phospholipid homeostasis, regulation of mitochondrion organization and ERMES complex, cytosol, nuclear envelope localization || 1 -0.10 0.12 1.24 1.23 0.81 0.46 -0.02 -0.11 0.71 -0.26 0.22 0.46 0.04 -0.05 0.16 0.37
1018 || orf19.3565 || || || Ortholog of C. dubliniensis CD36 : Cd36_19830, C. parapsilosis CDC317 : CPAR2_206470, Candida tenuis NRRL Y-1498 : CANTEDRAFT_113899 and Debaryomyces hansenii CBS767 : DEHA2C05676g || 1 0.28 0.02 0.75 0.89 0.55 0.31 -0.08 0.18 0.55 0.01 0.36 0.26 0.38 -0.06 0.19 0.35
1019 || orf19.2789 || || || Ortholog of C. dubliniensis CD36 : Cd36_07040, C. parapsilosis CDC317 : CPAR2_208700, Candida tenuis NRRL Y-1498 : CANTEDRAFT_108836 and Debaryomyces hansenii CBS767 : DEHA2F25674g || 1 0.27 -0.10 1.36 1.14 0.65 0.73 0.31 0.60 0.46 -0.40 0.27 0.49 0.24 0.13 0.47 0.44
1020 || orf19.2423 || ZCF11 || || Zn(II)2Cys6 transcription factor; required for wild-type filamentous growth; mRNA binds She3 || 1 0.18 0.26 1.59 0.85 0.60 0.64 0.11 -0.07 0.64 -0.17 0.12 0.63 0.69 0.22 0.46 0.49
1021 || orf19.6283 || || || Ortholog(s) have mitochondrion localization || 1 0.13 0.30 1.16 0.75 0.24 0.29 0.23 -0.17 0.33 -0.04 -0.26 0.56 0.31 0.17 0.52 0.35
1022 || orf19.6244 || || || Ortholog of C. dubliniensis CD36 : Cd36_06250, C. parapsilosis CDC317 : CPAR2_206820, Candida tenuis NRRL Y-1498 : CANTEDRAFT_125137 and Debaryomyces hansenii CBS767 : DEHA2G13266g || 1 0.04 0.06 0.53 0.56 0.21 0.37 -0.01 0.07 0.53 0.05 0.16 0.66 0.16 0.04 0.18 0.18
1023 || orf19.945 || VPS2 || || Ortholog(s) have role in intralumenal vesicle formation, protein retention in Golgi apparatus, protein targeting to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway || 1 0.00 0.28 0.90 0.62 -0.01 0.43 0.02 0.17 0.62 0.22 0.07 0.57 0.29 0.47 0.10 0.59
1024 || orf19.5954 || || || Ortholog(s) have enzyme activator activity, role in ascospore wall assembly, meiosis I, positive regulation of protein catabolic process and anaphase-promoting complex localization || 1 0.23 0.29 1.28 0.63 0.10 0.80 -0.07 0.14 0.86 0.05 0.30 0.47 0.47 0.48 0.39 0.47
1025 || orf19.5894 || || || Ortholog of S. cerevisiae : YEL023C, C. glabrata CBS138 : CAGL0I03168g, C. dubliniensis CD36 : Cd36_84380, Candida tenuis NRRL Y-1498 : CANTEDRAFT_101635 and Pichia stipitis Pignal : PICST_19384 || 1 0.40 0.10 1.11 1.10 0.40 0.74 -0.15 0.29 0.39 0.51 0.01 0.38 -0.10 0.35 0.09 0.49
1026 || orf19.5954 || || || Ortholog(s) have enzyme activator activity, role in ascospore wall assembly, meiosis I, positive regulation of protein catabolic process and anaphase-promoting complex localization || 1 0.03 0.30 1.63 1.34 0.12 0.98 0.31 0.52 0.33 -0.12 -0.09 0.61 -0.23 0.28 0.33 0.70
1027 || orf19.6222 || SPO22 || || Ortholog(s) have role in regulation of synaptonemal complex assembly and condensed nuclear chromosome localization || 1 0.08 0.13 0.68 0.71 0.00 0.63 0.00 0.06 0.42 0.09 -0.16 0.47 -0.40 0.18 0.01 0.25
1028 || orf19.7299.1 || || || Ortholog of Candida albicans WO-1 : CAWG_02179 || 1 0.39 0.15 0.65 0.81 0.31 0.13 0.01 0.53 0.37 -0.17 -0.27 0.27 -0.07 0.43 0.30 0.21
1029 || orf19.465 || IFF9 || || Predicted GPI-linked cell-wall protein; similar to Hyr1; induced in low iron; possibly an essential gene, disruptants not obtained by UAU1 method || 1 0.83 0.51 0.98 1.34 0.36 0.79 0.34 1.07 0.73 -0.23 -0.32 -0.08 -0.03 0.23 -0.41 1.09
1030 || orf19.2376 || || || Has domain(s) with predicted DNA 5'-adenosine monophosphate hydrolase activity, DNA binding activity and role in DNA repair || 1 1.08 0.52 0.93 0.95 0.44 0.82 0.29 0.83 0.50 0.12 -0.64 0.06 0.15 0.09 0.02 0.45
1031 || orf19.4570 || || || Ortholog of C. dubliniensis CD36 : Cd36_42090, Debaryomyces hansenii CBS767 : DEHA2C14872g, Pichia stipitis Pignal : PICST_74821 and Spathaspora passalidarum NRRL Y-27907 : SPAPADRAFT_58607 || 1 0.46 0.69 1.07 1.04 0.25 0.17 0.24 0.68 0.56 0.37 -0.37 -0.15 -0.04 0.10 0.22 0.34
1032 || orf19.1985 || || || Has aminoglycoside phosphotransferase and protein kinase domains; rat catheter and flow model biofilm induced || 1 0.58 0.53 0.69 1.09 -0.22 0.18 0.15 0.51 0.63 0.34 -0.66 -0.16 -0.43 -0.17 -0.02 0.36
1033 || orf19.7503 || CDA2 || || Putative chitin deacetylase; transcription is positively regulated by Tbf1p || 1 0.49 0.14 0.64 0.82 0.22 0.30 0.00 0.23 -0.17 -0.01 -0.46 0.36 0.06 -0.12 0.23 0.07
1034 || orf19.2479 || UGA4 || || Putative gamma-aminobutyric acid/polyamine permease; nitrogen catabolite repressed gene, induced in absence of preferred N sources; transcriptionally induced upon phagocytosis by macrophage; gene regulation by nitrogen source requires Gat1p || 1 0.36 0.40 0.56 0.80 0.11 0.64 0.32 0.13 0.26 -0.07 -0.18 0.42 0.02 -0.54 0.15 0.28
1035 || orf19.6550 || || || Putative mitochondrial outer membrane protein; regulated by Sef1p-, Sfu1p-, and Hap43p || 1 0.55 0.39 0.88 0.80 0.45 0.83 0.21 0.22 0.25 -0.06 -0.18 0.62 0.04 -0.60 0.36 0.32
1036 || orf19.6498 || || || Ortholog(s) have role in RNA polymerase II complex localization to nucleus, RNA polymerase III complex localization to nucleus and DNA-directed RNA polymerase II, holoenzyme, cytoplasm localization || 1 0.24 0.05 0.84 0.53 0.29 0.73 0.05 0.34 0.23 0.05 0.09 0.34 0.04 -0.36 0.34 0.06
1037 || orf19.4741 || || || Protein of unknown function; C. albicans- and C. dubliniensis specific gene; rat catheter biofilm repressed || 1 0.41 -0.04 1.32 0.82 0.66 0.66 0.20 0.59 0.16 0.23 -0.26 1.11 0.01 -0.04 0.10 0.51
1038 || orf19.1844 || || || Protein similar to ferric reductase Fre10p || 1 0.18 0.03 1.00 0.44 0.57 0.86 -0.16 0.41 -0.06 0.20 -0.03 0.25 -0.06 0.14 0.33 0.38
1039 || orf19.7652 || CKA1 || || Putative alpha subunit (catalytic subunit) of protein kinase CK2; Cka1p and Cka2p have a common target with respect to fluconazole resistance; synthetically lethal with CKA2; flucytosine induced || 1 0.22 0.06 0.54 0.60 0.27 0.60 -0.02 0.25 -0.07 0.31 0.28 0.40 0.12 0.14 0.23 0.25
1040 || orf19.4292 || || || Ortholog(s) have SNAP receptor activity, role in Golgi to vacuole transport, vacuole inheritance and Golgi apparatus, endosome localization || 1 0.58 0.44 0.60 0.86 0.56 0.80 0.09 -0.11 0.19 0.21 0.53 0.35 -0.38 0.22 0.57 0.46
1041 || orf19.6444 || || || Ortholog(s) have role in cellular response to amino acid starvation, meiosis, negative regulation of TOR signaling cascade, regulation of autophagic vacuole assembly || 1 0.37 0.35 0.27 1.49 1.18 1.32 0.03 0.14 0.27 0.27 0.39 0.43 0.15 0.35 0.69 0.22
1042 || orf19.3077 || VID21 || || Subunit of the NuA4 histone acetyltransferase complex; soluble protein in hyphae; Spider biofilm repressed || 1 0.58 0.68 0.07 0.93 0.69 1.03 0.18 0.04 0.39 0.60 0.29 0.16 0.16 0.67 0.89 0.32
1043 || orf19.4965 || || || Protein of unknown function; rat catheter biofilm induced || 1 0.74 0.54 0.29 0.45 0.81 1.20 0.36 0.11 0.09 0.12 -0.33 0.64 0.29 -0.22 0.76 -0.12
1044 || orf19.4420 || || || Predicted component of the core factor rDNA transcription factor complex; required for transcription of 35S rRNA genes by RNA polymerase I in S. cerevisiae; possibly an essential gene, disruptants not obtained by UAU1 method || 1 1.70 0.82 0.50 0.81 1.06 1.46 0.35 0.26 0.26 0.38 0.04 0.15 -0.02 -0.30 0.48 0.35
1045 || orf19.6243 || VPS34 || || Autophosphorylated class III phosphatidylinositol 3-kinase; required for normal vesicle transport, hyphal growth, fibroblast adherence, virulence in mouse systemic infection; growth-regulated; caspofungin and hydrogen peroxide sensitivity || 1 1.01 0.15 0.65 0.71 0.83 0.64 0.06 -0.00 0.52 -0.16 -0.12 0.39 -0.05 -0.17 0.82 -0.04
1046 || orf19.4673 || BMT9 || || Beta-mannosyltransferase, 9-gene family that includes characterized genes BMT1, BMT2, BMT3, and BMT4 with roles in beta-1,2-mannosylation of cell wall phosphopeptidomannan; regulated by Sef1, Sfu1, Hap43; rat catheter biofilm repressed || 1 0.96 -0.06 0.97 1.55 1.58 1.82 0.30 0.38 1.34 0.30 0.43 0.03 -0.27 -0.57 0.98 0.40
1047 || orf19.4239 || || || Planktonic growth-induced gene || 1 0.91 0.06 0.60 1.00 0.83 2.50 0.09 -0.10 0.98 0.09 0.26 0.30 -0.16 -1.26 0.27
1048 || orf19.1827 || || || Protein of unknown function; flow model biofilm induced; induced by alpha pheromone in SpiderM medium || 1 0.60 0.13 0.68 0.52 0.56 1.36 -0.16 -0.17 0.26 -0.40 -0.15 0.26 -0.25 0.29 0.31 -0.34
1049 || orf19.6475 || || || Protein of unknown function; flow model biofilm induced || 1 0.42 0.23 0.88 0.62 0.95 1.02 0.26 0.04 0.43 -0.25 0.49 0.57 -0.10 0.67 0.14 -0.33
1050 || orf19.7037 || YAE1 || || Ortholog(s) have role in ribosomal large subunit biogenesis, translational initiation and cytoplasm, nucleus localization || 1 0.16 0.28 0.42 0.25 0.78 1.15 0.46 0.13 0.43 -0.06 0.09 0.18 0.04 0.39 0.26 -0.08
1051 || orf19.1950 || || || Ortholog(s) have phosphatase activity || 1 0.19 0.24 0.78 0.68 0.70 0.95 0.39 0.30 0.38 -0.07 -0.13 -0.22 0.22 0.10 0.71 -0.47
1052 || orf19.1008 || || || Ortholog of Candida albicans WO-1 : CAWG_01856 || 1 0.71 1.18 0.70 3.44 0.30 1.71 0.51 1.20 -0.25 0.66 -0.38 1.38 1.30 -0.17
1053 || orf19.5616 || || || Ortholog of C. dubliniensis CD36 : Cd36_63740, C. parapsilosis CDC317 : CPAR2_503850, Pichia stipitis Pignal : PICST_32045 and Candida guilliermondii ATCC 6260 : PGUG_00070 || 1 0.14 0.44 0.70 1.02 0.42 0.76 0.10 0.28 -0.25 0.69 0.33 -0.22 0.68 0.06 0.13 -0.13
1054 || orf19.2517 || || || Predicted membrane transporter, member of the drug:proton antiporter (12 spanner) (DHA1) family, major facilitator superfamily (MFS) || 1 0.03 -0.09 0.94 1.17 0.10 0.48 -0.23 0.71 0.78 0.10 -0.41 0.51 0.34 -0.07 0.37 0.26
1055 || orf19.6464 || || || Protein of unknown function; induced upon adherence to polystyrene; oxidative stress-induced via Cap1 || 1 0.22 0.20 0.64 0.50 0.20 0.26 -0.11 -0.00 0.54 0.16 -0.02 0.18 -0.26 0.16 0.10 0.40
1056 || orf19.2766 || || || Dubious open reading frame || 1 0.31 -0.23 0.87 1.07 0.24 -0.07 0.82 -0.05 -0.47 0.17 -0.74 0.29
1057 || orf19.4450 || ZCF23 || || Predicted Zn(II)2Cys6 transcription factor; ortholog of S. cerevisiae Gsm1; flow model biofilm induced || 1 0.28 -0.03 1.03 0.69 0.07 1.05 -0.24 0.39 0.64 0.23 -0.37 0.10 -0.58 0.21 0.19 0.01
1058 || orf19.515 || || || Has domain(s) with predicted nucleic acid binding, zinc ion binding activity || 1 0.33 -0.24 0.73 0.66 0.25 1.05 -0.15 -0.25 0.37 0.06 -0.30 0.11 -0.14 -0.12 0.04 -0.17
1059 || orf19.634 || || || Ortholog of C. dubliniensis CD36 : Cd36_30370, Candida tropicalis MYA-3404 : CTRG_00536 and Candida albicans WO-1 : CAWG_01831 || 1 0.28 -0.17 2.12 2.33 1.10 2.48 -0.50 -0.17 2.06 0.44 -0.26 0.18 -0.19 -0.15 0.16 -0.40
1060 || orf19.2025 || || || Dubious open reading frame || 1 -0.13 -0.56 1.30 1.56 0.45 1.43 0.08 0.20 1.06 -0.14 -0.21 0.44 -0.12 0.02 -0.14 -0.01
1061 || orf19.1524 || SPR3 || || Septin; mutant has no obvious phenotype || 1 0.09 -0.00 1.42 1.71 0.34 1.21 -0.25 -0.11 2.30 0.62 -0.11 -0.69 -0.30 -0.12 -0.55 0.17
1062 || orf19.2530 || || || Dubious open reading frame || 1 0.33 0.22 1.10 0.64 -0.27 1.02 0.17 -0.32 0.99 -0.05 -0.25 -0.56 -0.38 -0.23 0.27 0.07
1063 || orf19.5177 || || || Ortholog of Candida albicans WO-1 : CAWG_05627 || 1 0.15 0.26 0.80 0.26 0.27 0.05 -0.17 -0.10 0.65 -0.43 -0.11 -0.40 0.38 0.25 -0.02 0.25
1064 || orf19.6045 || || || Putative phosphatidylserine decarboxylase; involved in phosphatidylethanolamine; Spider biofilm repressed || 1 -0.04 0.30 0.75 0.34 0.52 -0.16 0.02 -0.04 0.41 -0.12 -0.09 -0.23 0.68 0.31 -0.02 0.24
1065 || orf19.1228 || HAP2 || || CCAAT-binding transcription factor; regulates low-iron induction of FRP1; in these conditions CBF comprises Hap43 and probably Hap2 and Hap3; possibly essential, disruptants not obtained by UAU1 method; Cap1-dependent induction in low iron || 1 0.15 0.29 0.49 0.26 0.33 0.16 -0.20 -0.26 0.07 -0.11 -0.14 0.12 0.56 0.66 -0.01 0.15
1066 || orf19.4665 || || || Protein of unknown function; Spider biofilm induced || 1 0.19 0.01 0.79 0.48 0.12 0.36 -0.15 -0.14 0.37 -0.12 -0.26 -0.04 0.54 0.81 -0.11 0.32
1067 || orf19.1856 || || || Ortholog(s) have histone deacetylase activity || 1 0.25 0.27 0.40 0.41 0.20 0.11 -0.02 0.21 0.33 -0.09 0.14 -0.00 0.46 0.77 -0.10 -0.05
1068 || orf19.4665 || || || Protein of unknown function; Spider biofilm induced || 1 0.43 0.56 0.62 0.50 0.34 0.53 0.18 0.21 0.27 -0.28 0.35 0.11 0.94 0.95 -0.28 0.12
1069 || orf19.7547 || || || Ortholog(s) have phosphatidylinositol-3-phosphate binding, ubiquitin-protein ligase activity, role in protein ubiquitination and cytosol, fungal-type vacuole membrane, late endosome, nucleus localization || 1 0.12 0.17 0.60 0.75 0.10 0.64 0.02 0.17 0.30 -0.39 -0.12 -0.08 0.22 0.46 0.13 0.14
1070 || orf19.6138 || || || Protein similar to ferric reductase Fre10p; possibly an essential gene, disruptants not obtained by UAU1 method || 1 0.05 0.17 0.68 0.63 0.09 0.41 -0.28 0.11 0.09 -0.20 -0.25 -0.14 -0.16 0.52 -0.34 0.04
1071 || orf19.6450 || || || Protein of unknown function || 1 -0.15 0.35 1.05 1.21 0.30 -0.49 0.03 0.96 -0.10 0.03 -0.44 0.08 0.58 -0.41 0.56
1072 || orf19.4589 || || || Ortholog(s) have polyamine oxidase activity, role in pantothenate biosynthetic process, polyamine catabolic process and cytoplasm localization || 1 0.11 0.06 1.00 0.74 0.18 0.06 0.16 0.08 0.78 -0.07 -0.28 -0.10 0.46 0.62 -0.35 0.10
1073 || orf19.4923 || || || Predicted membrane transporter; sugar porter (SP) family member, major facilitator superfamily; caspofungin induced; Spider biofilm induced || 1 -0.17 -0.10 0.71 0.75 -0.31 0.23 -0.20 0.15 0.61 -0.02 -0.50 -0.15 0.06 0.43 -0.40 0.26
1074 || orf19.4949 || || || Ortholog of C. parapsilosis CDC317 : CPAR2_801735, C. dubliniensis CD36 : Cd36_84090, Candida orthopsilosis Co 90-125 : CORT_0B03960 and Spathaspora passalidarum NRRL Y-27907 : SPAPADRAFT_141253 || 1 0.00 -0.18 1.15 0.79 -0.38 0.49 0.10 0.07 0.47 -0.24 -0.03 -0.55 0.16 0.69 -0.13 -0.06
1075 || orf19.4905 || || || Putative MFS transporter; Hap43p-induced gene; also regulated by regulated by Sef1p and Sfu1p; repressed in a ssr1 null mutant || 1 0.67 -0.38 0.93 0.84 -0.43 0.40 0.17 0.16 0.58 -0.67 0.06 -0.26 0.23 0.72 -0.27 0.15
1076 || orf19.5866 || || || Ortholog of Candida albicans WO-1 : CAWG_02737 || 1 0.80 1.05 0.45 1.44 0.08 0.42 0.88 0.19 1.02 0.30 0.83 -0.06 0.51 0.68 0.00 -0.79
1077 || orf19.4719 || CWH41 || || Processing alpha glucosidase I, involved in N-linked protein glycosylation and assembly of cell wall beta 1,6 glucan; rat catheter biofilm repressed || 1 0.19 0.60 0.22 0.57 0.25 0.01 0.22 0.16 0.68 0.34 0.20 0.33 0.47 -0.30 -0.06 -0.13
1078 || orf19.4404 || PGA49 || || Putative GPI-anchored protein || 1 0.50 0.63 0.54 0.74 0.23 0.10 0.62 -0.03 0.89 0.43 0.22 -0.11 0.27 -0.58 0.33 -0.54
1079 || orf19.4787 || || || Ortholog(s) have cytoplasm, nucleus localization || 1 0.47 0.98 0.65 0.60 0.30 0.13 0.55 0.06 0.55 0.19 0.28 -0.19 0.75 -0.21 0.48 -0.37
1080 || orf19.2922 || || || Ortholog(s) have double-stranded DNA binding activity, role in reciprocal meiotic recombination, synapsis and condensed nuclear chromosome localization || 1 0.58 1.35 0.05 0.44 0.41 0.32 1.09 -0.01 1.59 -0.39 0.56 0.21 1.23 -0.63 0.31 -0.85
1081 || orf19.3210 || || || Predicted protein of unknown function; Plc1-regulated || 1 0.84 1.21 0.46 0.37 1.05 -0.51 0.14 -0.28 0.71 0.40 0.07 1.00 0.18
1082 || orf19.6028 || HGC1 || || Hypha-specific G1 cyclin-related protein involved in regulation of morphogenesis, biofilm formation; Cdc28-Hgc1 maintains Cdc11 S394 phosphorylation during hyphal growth; required for virulence in mice; regulated by Nrg1, Tup1, farnesol || 1 1.12 1.39 0.86 1.06 1.27 -0.19 0.24 -0.11 1.02 1.20 -0.49 -1.17 0.88 -1.24 0.04 -0.82
1083 || orf19.4510 || IFA4 || || Protein of unknown function; oxidative stress-induced via Cap1 || 1 0.90 0.39 0.59 0.60 0.95 0.11 0.34 0.31 1.28 0.93 0.16 -0.35 0.81 -0.49 -0.44 -0.08
1084 || orf19.7270 || || || Protein of unknown function; Spider biofilm repressed || 1 0.06 -0.21 0.53 0.54 -0.13 0.17 0.48 0.43 0.60 -0.29 0.19 0.19 0.17 -0.28 0.44 0.03
1085 || orf19.4898 || || || Putative protein of unknown function; induced by prostaglandins || 1 0.05 0.15 0.41 0.65 0.45 0.50 0.38 0.50 0.24 -0.79 -0.03 0.17 0.34 -0.20 0.77 0.19
1086 || orf19.5544 || SAC6 || || Fimbrin; actin filament bundling protein; transcript regulated by Nrg1 and Mig1; protein level decreases in stationary phase || 1 0.16 0.01 0.44 0.34 -0.03 0.22 0.22 0.26 -0.04 -0.33 0.49 0.13 -0.09 0.31 0.53 0.17
1087 || orf19.4019 || || || Ortholog(s) have protein phosphatase regulator activity, role in negative regulation of DNA damage checkpoint, protein dephosphorylation and cytoplasm, nucleus localization || 1 0.47 0.50 0.40 0.66 -0.22 0.14 0.28 0.37 0.16 -0.24 0.27 0.26 0.02 0.15 0.54 0.03
1088 || orf19.2366 || || || Has domain(s) with predicted DNA binding activity and role in DNA integration || 1 0.48 0.60 1.52 0.84 -0.00 0.97 0.40 0.88 0.41 -0.61 0.50 0.69 -0.10 0.62 0.61 -0.71
1089 || orf19.6861 || || || Ortholog(s) have ubiquitin-protein ligase activity and role in anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process, chromatin assembly, protein ubiquitination || 1 0.51 0.34 0.68 0.04 0.06 0.19 0.42 0.32 0.23 -0.14 0.17 0.57 0.64 0.17 0.15 -0.01
1090 || orf19.7297 || || || Putative cystathionine gamma-synthase; decreased levels in stationary phase cultures; Hog1p-induced; Gcn4p-regulated || 1 -0.02 0.29 0.46 0.26 0.06 0.25 0.33 0.02 0.67 -0.72 0.47 0.82 0.41 -0.01 0.12 0.39
1091 || orf19.4900 || MNN12 || || Predicted alpha-1,3-mannosyltransferase activity with a role in protein glycosylation || 1 0.32 0.23 0.52 0.16 0.29 0.42 0.17 -0.08 0.46 -0.21 0.44 0.98 0.07 -0.30 0.24 -0.03
1092 || orf19.322 || || || Ortholog of Candida albicans WO-1 : CAWG_02670 || 1 0.52 0.27 0.54 0.23 0.04 1.40 0.45 0.56 0.57 -0.33 1.30 0.52 0.27 -0.59 0.40 -0.17
1093 || orf19.2908 || || || Predicted oxidoreductase; rat catheter biofilm induced || 1 -0.13 0.49 0.70 0.02 0.00 -0.10 0.06 0.33 0.46 -0.28 0.29 0.53 0.52 0.11 0.02 0.62
1094 || orf19.1371 || || || Ortholog of C. dubliniensis CD36 : Cd36_23880, C. parapsilosis CDC317 : CPAR2_806590, Candida tenuis NRRL Y-1498 : CANTEDRAFT_92769 and Debaryomyces hansenii CBS767 : DEHA2B13376g || 1 -0.12 0.20 0.57 0.06 0.10 -0.09 -0.03 0.28 0.22 -0.18 -0.08 0.23 0.37 0.43 -0.31 0.46
1095 || orf19.3551 || DAD2 || || Essential subunit of the Dam1 (DASH) complex, which acts in chromosome segregation by coupling kinetochores to spindle microtubules || 1 0.72 0.65 1.23 1.09 0.40 -0.30 -0.16 0.07 0.31 -0.31 0.49 0.46 0.34 0.63 -1.01 0.49
1096 || orf19.1428 || DUO1 || || Subunit of the Dam1 (DASH) complex, which acts in chromosome segregation by coupling kinetochores to spindle microtubules || 1 0.23 0.13 0.67 0.47 0.33 0.11 0.17 0.28 -0.08 0.23 0.68 0.31 0.59 0.70 -0.53 0.53
1097 || orf19.1428 || DUO1 || || Subunit of the Dam1 (DASH) complex, which acts in chromosome segregation by coupling kinetochores to spindle microtubules || 1 0.08 0.03 0.87 0.68 0.07 0.16 0.09 0.33 -0.08 0.33 0.32 0.36 0.36 0.52 -0.41 0.75
1098 || orf19.1428 || DUO1 || || Subunit of the Dam1 (DASH) complex, which acts in chromosome segregation by coupling kinetochores to spindle microtubules || 1 0.08 -0.03 0.64 0.35 0.17 0.03 0.27 0.54 0.12 0.35 0.20 0.32 0.53 0.77 -0.57 0.89
1099 || orf19.1428 || DUO1 || || Subunit of the Dam1 (DASH) complex, which acts in chromosome segregation by coupling kinetochores to spindle microtubules || 1 0.19 -0.07 0.57 0.58 0.08 0.09 -0.10 0.30 0.20 0.44 0.30 0.39 0.56 0.71 -0.66 0.49
1100 || orf19.1428 || DUO1 || || Subunit of the Dam1 (DASH) complex, which acts in chromosome segregation by coupling kinetochores to spindle microtubules || 1 0.06 0.12 0.72 0.57 -0.10 0.11 -0.19 0.21 0.04 0.26 0.28 0.35 -0.12 0.75 -0.60 0.36
1101 || orf19.1622 || YCG1 || || Putative condensin G || 1 -0.14 0.02 0.95 0.49 -0.34 0.06 0.11 0.08 0.71 1.08 0.09 0.42 0.40 0.93 -0.38 0.82
1102 || orf19.4112 || || || Ortholog(s) have 8-oxo-dGDP phosphatase activity, ATP binding, magnesium ion binding, thiamine binding, thiamine diphosphokinase activity, role in thiamine biosynthetic process and cytosol localization || 1 0.09 0.08 0.66 0.18 0.06 -0.12 0.12 0.19 0.22 0.24 0.10 0.16 0.14 -0.04 -0.02 0.24
1103 || orf19.5287 || || || Ortholog of C. dubliniensis CD36 : Cd36_30690, C. parapsilosis CDC317 : CPAR2_204140, Debaryomyces hansenii CBS767 : DEHA2F16940g and Candida tropicalis MYA-3404 : CTRG_00570 || 1 0.16 0.03 0.83 0.49 -0.30 -0.46 0.19 0.25 0.21 0.00 -0.10 0.56 0.20 0.64 -0.10 0.73
1104 || orf19.315 || || || Ortholog of C. dubliniensis CD36 : Cd36_83120, C. parapsilosis CDC317 : CPAR2_103220, Candida tenuis NRRL Y-1498 : CANTEDRAFT_112860 and Debaryomyces hansenii CBS767 : DEHA2G08360g || 1 -0.05 0.23 0.71 0.21 -0.53 -0.19 0.09 0.49 0.12 0.14 0.46 0.40 0.11 0.65 -0.27 0.72
1105 || orf19.7020 || || || Protein similar to S. cerevisiae Kex1p, which is a pheromone-processing peptidase; possible Kex2p substrate || 1 0.31 0.47 0.64 0.42 -0.27 -0.23 0.59 0.33 0.32 0.19 0.77 0.50 0.59 0.68 0.14 0.49
1106 || orf19.3317 || MED22 || || RNA polymerase II mediator complex subunit || 1 0.28 0.41 0.68 0.64 0.22 -0.05 0.33 0.03 0.32 -0.05 0.61 0.58 0.35 0.51 0.45
1107 || orf19.6786 || || || Protein of unknown function; flow model biofilm induced || 1 0.15 0.55 1.80 1.08 -0.32 -0.42 0.52 0.31 0.09 -0.14 0.63 0.98 0.56 0.70 0.12 0.68
1108 || orf19.1135 || CAS1 || || Putative transcription factor with Ku70/Ku80 beta-barrel DNA-binding motif; involved in telomerase regulation and telomere protection; mutation causes marginal increase in caspofungin sensitivity || 1 0.27 0.48 1.30 0.63 -0.24 -0.36 0.62 0.10 0.33 -0.16 0.32 0.27 0.50 0.68 -0.25 0.53
1109 || orf19.1773 || RAP1 || || Transcription factor; binds telomeres and regulatory sequences in DNA; involved in telomere maintenance; represses hyphal growth under yeast-favoring conditions; similar to (but shorter than) S. cerevisiae Rap1 || 1 0.22 0.24 1.47 0.91 -0.67 0.12 0.50 -0.05 0.31 -0.22 0.47 0.24 0.54 0.24 -0.01 0.42
1110 || orf19.6080 || || || Ortholog(s) have role in mitotic spindle orientation checkpoint and spindle pole body localization || 1 0.08 0.20 1.18 0.41 -0.48 0.01 0.29 0.34 0.30 -0.26 0.04 0.34 0.16 0.05 -0.32 0.21
1111 || orf19.5814 || || || Protein of unknown function; Spider biofilm induced || 1 -0.00 0.16 0.82 0.47 -0.36 -0.22 0.08 0.33 0.20 0.18 0.02 0.24 0.00 0.13 -0.02 0.14
1112 || orf19.1725 || || || Putative adhesin-like protein || 1 0.29 0.03 1.08 1.07 -0.27 0.08 0.54 0.57 0.39 -0.44 0.01 0.05 0.44 0.09 -0.07 0.44
1113 || orf19.2507 || ARP9 || || Protein similar to S. cerevisiae Arp3p, a component of the Arp2/3 complex involved in actin-dependent processes; likely to be essential for growth, based on an insertional mutagenesis strategy || 1 -0.03 -0.10 0.64 0.52 -0.21 -0.17 -0.04 0.00 -0.05 -0.13 0.12 0.65 0.16 0.05 -0.03 0.28
1114 || orf19.6248 || || || Ortholog of C. dubliniensis CD36 : Cd36_06210, Candida tropicalis MYA-3404 : CTRG_04227 and Candida albicans WO-1 : CAWG_00750 || 1 -0.29 0.21 0.46 0.54 0.11 0.27 -0.14 0.08 0.14 0.38 0.38 0.09 0.23 0.12 0.47
1115 || orf19.6493 || || || Ortholog of C. dubliniensis CD36 : Cd36_72020 and Candida albicans WO-1 : CAWG_05570 || 1 -0.93 -0.08 1.27 1.68 0.10 -0.77 -0.24 0.59 0.41 0.37 0.71 -0.45 0.81
1116 || orf19.2911 || SEC3 || || Predicted subunit of the exocyst complex, involved in exocytosis; required for hyphal growth after the first septin ring formation; interacts with septins Cdc3p, Cdc10p, and Cdc11p; localizes to a crescent on the surface of the hyphal tip || 1 -0.11 -0.05 0.99 0.66 0.13 0.52 -0.02 -0.03 0.26 0.26 0.01 0.26 0.20 0.41 0.13 0.86
1117 || orf19.3643 || || || Protein of unknown function; Hap43-repressed gene || 1 -0.35 -0.10 0.78 0.77 -0.25 0.95 -0.12 -0.16 0.50 0.44 -0.06 0.70 0.21 0.27 -0.11 0.47
1118 || orf19.4847 || || || Ortholog of Candida albicans WO-1 : CAWG_00450 || 1 -0.37 0.03 0.26 0.09 0.53 -0.05 -0.18 0.56 0.35 -0.16 0.19 -0.21
1119 || orf19.679 || FGR39 || || Protein lacking an ortholog in S. cerevisiae; transposon mutation affects filamentous growth || 1 -0.00 -0.02 0.32 0.05 -0.38 0.25 0.08 -0.30 0.51 0.42 -0.00 0.25 0.48 0.18 -0.15 0.29
1120 || orf19.6588 || NBP2 || || Protein containing an SH3 domain; involved in vacuolar fusion in hyphae; mutants form multiple germ tubes; Spider biofilm induced || 1 -0.28 -0.22 0.60 -0.02 0.13 0.68 0.19 -0.16 0.78 0.49 0.01 0.38 0.64 0.45 -0.00 0.42
1121 || orf19.6900 || || || Ortholog(s) have role in establishment or maintenance of cell polarity, mitochondrial genome maintenance, mitochondrion inheritance, phospholipid transport, protein import into mitochondrial outer membrane || 1 -0.14 0.07 0.44 0.36 -0.09 0.40 0.46 -0.17 0.50 0.13 -0.14 0.39 -0.17 0.49 0.26 0.44
1122 || orf19.2943.5 || || || Ortholog of Candida albicans WO-1 : CAWG_05543 || 1 0.38 0.17 0.48 1.00 -0.46 0.97 0.83 0.03 1.74 0.30 0.17 0.79 0.00 0.81 0.56
1123 || orf19.6581 || || || Ortholog(s) have palmitoyltransferase activity, role in protein palmitoylation and endoplasmic reticulum localization || 1 0.62 -0.00 0.77 0.58 -0.27 0.16 0.30 0.05 0.98 0.45 0.10 0.45 -0.17 0.20 0.13 0.34
1124 || orf19.1571 || ATO7 || || Putative fungal-specific transmembrane protein || 1 0.19 -0.08 1.09 1.70 -0.40 1.36 1.29 0.13 1.63 0.60 0.59 0.76 -0.58 0.73
1125 || orf19.3193 || FCR3 || || bZIP transcription factor; ortholog of S. cerevisiae Yap3; partially complements fluconazole sensitivity of S. cerevisiae pdr1 pdr3; Hap43-induced; required for yeast cell adherence to silicone substrate; flow model biofilm repressed || 1 0.03 0.09 0.41 0.31 -0.13 0.37 0.10 0.07 0.45 0.42 -0.03 0.03 0.47 0.37 0.05 0.04
1126 || orf19.4678 || || || Predicted triglyceride lipase; Spider biofilm induced || 1 0.37 -0.27 0.78 0.93 -0.06 0.70 0.04 0.53 0.81 0.36 0.04 0.40 0.74 0.40 0.01 0.29
1127 || orf19.6949 || || || Ortholog of Candida albicans WO-1 : CAWG_02687 || 1 0.44 -0.17 1.28 -0.51 0.78 0.23 0.60 0.54 0.00 0.69 0.63 -0.80 -0.10
1128 || orf19.4724 || || || Ortholog(s) have RNA binding activity, role in spliceosomal complex assembly and U2-type prespliceosome localization || 1 0.30 0.33 0.94 1.30 0.72 0.35 0.33 0.47 0.57 0.30 0.72 0.39 0.04 0.82 -0.22 0.32
1129 || orf19.4566 || || || Protein similar to S. cerevisiae Rot1p, which has roles in cytoskeletal dynamics and cell wall biosynthesis; predicted Kex2p substrate || 1 -0.43 -0.28 2.09 2.55 0.99 0.20 0.13 0.18 0.79 0.43 1.62 -0.30 0.80 0.36 0.50
1130 || orf19.5155 || CHS6 || || Protein with tetratricopeptide repeats (TPRs); ortholog of S. cerevisiae Chs6, which has role in localizing chitin synthase; Cyr1-regulated in hyphae; possibly essential, disruptants not obtained by UAU1 method; flow model biofilm repressed || 1 -0.08 -0.12 0.31 0.47 0.07 -0.02 0.14 0.27 0.31 -0.03 0.52 0.13 0.57 0.20 0.00 -0.07
1131 || orf19.6205 || || || Ortholog of C. dubliniensis CD36 : Cd36_06550, C. parapsilosis CDC317 : CPAR2_209030, Candida tenuis NRRL Y-1498 : CANTEDRAFT_111035 and Debaryomyces hansenii CBS767 : DEHA2F25300g || 1 0.14 -0.09 0.73 0.99 -0.45 -0.12 0.23 0.47 0.15 0.27 0.26 0.39 0.81 -0.20 -0.06 0.13
1132 || orf19.6169 || ATO1 || || Putative fungal-specific transmembrane protein; induced by Rgt1; Spider biofilm induced || 1 -0.25 0.31 1.23 1.60 -1.00 0.50 -0.61 -0.25 -0.29 0.18 -0.70 0.62 0.06
1133 || orf19.2804 || || || Ortholog of C. dubliniensis CD36 : Cd36_83980, C. parapsilosis CDC317 : CPAR2_102620, Candida tenuis NRRL Y-1498 : CANTEDRAFT_134550 and Debaryomyces hansenii CBS767 : DEHA2D12100g || 1 -0.06 -0.01 0.39 0.90 -0.67 -0.08 4.11 -0.00 0.31 0.99 -0.15 0.42
1134 || orf19.2449 || || || Putative adhesin-like protein; macrophage-induced gene || 1 0.42 0.73 0.22 1.24 0.44 0.46 -0.41 -0.50 3.90 0.69 -0.44 0.31 -0.50 -0.93 0.12 0.55
1135 || orf19.6164 || || || Ortholog of Candida albicans WO-1 : CAWG_02424 || 1 1.21 0.33 0.53 0.29 0.63 0.68 0.89 0.43 4.49 0.26 -0.14 -0.06 -1.38 0.35 0.75
1136 || orf19.7275 || FGR24 || || Protein encoded in retrotransposon Zorro2 with similarity to retroviral endonuclease-reverse transcriptase proteins; lacks an ortholog in S. cerevisiae; transposon mutation affects filamentous growth || 1 0.11 1.47 0.58 0.20 0.35 1.08 0.52 -0.13 2.84 0.49 0.35 -0.59 0.50 0.48 1.17
1137 || orf19.1722 || || || Ortholog of Candida albicans WO-1 : CAWG_02462 || 1 0.93 1.07 1.47 1.34 1.01 0.24 0.54 1.01 7.11 -0.03 3.07 -0.12 1.15 0.66 -0.35
1138 || orf19.420 || || || Protein of unknown function || 1 0.19 0.88 -0.35 -0.06 0.51 0.41 0.57 0.51 3.39 0.04 1.47 -0.21 1.04 0.11 0.47 -0.40
1139 || orf19.2869 || || || Ortholog of C. dubliniensis CD36 : Cd36_46110, Candida tropicalis MYA-3404 : CTRG_03792 and Candida albicans WO-1 : CAWG_03165 || 1 1.02 0.58 -0.01 0.09 1.11 -0.49 0.45 -0.10 2.67 0.74 0.74 -0.36 1.42 -0.22 1.01 -0.51
1140 || orf19.541 || || || Has domain(s) with predicted oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors activity || 1 0.28 0.28 0.21 0.29 0.20 0.24 0.52 0.44 0.96 0.12 0.13 -0.05 0.01 0.06 0.69 -0.05
1141 || orf19.3280 || || || Ortholog of Candida albicans WO-1 : CAWG_01435 || 1 0.22 -0.35 -0.44 0.48 0.30 0.38 0.50 -0.10 1.88 -0.00 1.18 0.15 -0.37 0.65
1142 || orf19.4320 || || || Ortholog of Candida albicans WO-1 : CAWG_04676 || 1 0.52 0.08 0.56 0.83 0.09 1.53 0.13 -0.60 1.47 -0.40 0.82 0.55 -0.31 1.01 0.47
1143 || orf19.7557 || FGR46 || || Protein lacking an ortholog in S. cerevisiae; transposon mutation affects filamentous growth || 1 0.85 -0.23 0.44 0.94 0.12 0.44 -0.31 0.17 1.62 -0.29 -0.08 0.17 0.09 0.47 0.75 0.37
1144 || orf19.2071 || || || Protein of unknown function; induced by alpha pheromone in SpiderM medium || 1 0.44 1.15 0.09 2.88 0.67 0.75 0.23 -0.47 2.86 1.15 0.71 0.01 0.29 0.23 0.96
1145 || orf19.2766 || || || Dubious open reading frame || 1 -0.14 0.21 -0.19 0.72 0.33 -0.01 -0.19 0.66 0.55 0.09 0.66 0.22
1146 || orf19.5846 || || || Putative TFIIH and nucleotide excision repair factor 3 complex subunit; possibly an essential gene, disruptants not obtained by UAU1 method || 1 -0.25 -0.18 0.43 0.09 -0.07 -0.10 0.06 0.06 0.72 -0.07 0.41 -0.15 0.31 0.08 0.21 0.31
1147 || orf19.1969 || CCW14 || || Putative mannoprotein of cell wall with role in response to stress; increased mRNA abundance observed in cyr1 homozygous mutant (hyphal or yeast-form cells) and in ras1 homozygous mutant (yeast-form cells) || 1 -0.27 -0.19 0.23 0.51 0.43 -0.46 -0.63 1.30 -0.34 0.97 -0.02 0.56 -0.25 -0.15
1148 || orf19.599 || || || Dubious open reading frame || 1 -0.03 -0.44 0.41 0.83 0.94 0.48 -0.06 -0.07 0.81 -0.26 0.33 -0.11 0.02 0.10 -0.22 0.13
1149 || orf19.1204 || || || Phosphorylated protein of unknown function; transcript is upregulated clinical isolates from HIV positive patients with oral candidiasis || 1 -0.27 -0.21 0.52 0.88 0.05 0.21 0.13 -0.08 0.38 -0.07 0.11 0.50 0.11 -0.08 -0.00 -0.19
1150 || orf19.6179 || || || Ortholog of Candida albicans WO-1 : CAWG_03090 || 1 -0.50 -0.28 1.58 -0.12 -0.68 -0.18 1.56 -0.04 0.40 0.07 0.27 0.56
1151 || orf19.4789 || || || Has domain(s) with predicted metal ion binding activity || 1 -0.70 0.02 0.55 1.91 -0.06 0.64 -0.46 -0.50 1.36 -0.15 -0.44 0.04 -0.51 -0.24 -0.43 0.02
1152 || orf19.302 || || || Ortholog(s) have Rab guanyl-nucleotide exchange factor activity, role in ER to Golgi vesicle-mediated transport and TRAPP complex, cytosol, nucleus localization || 1 0.04 -0.64 0.66 0.54 -0.42 0.39 -0.24 -0.08 0.95 -0.05 0.15 0.22 -0.27 -0.08 -0.47 0.06
1153 || orf19.5587 || || || Protein of unknown function; transcript is upregulated in clinical isolates from HIV+ patients with oral candidiasis || 1 -0.05 -0.17 -0.10 0.79 -0.19 0.41 -0.58 -0.62 0.99 -0.44 -0.45 0.68 -0.24 -0.60 -0.11 0.07
1154 || orf19.4728 || || || Ortholog(s) have role in histone deacetylation, negative regulation of meiosis and Set3 complex localization || 1 0.51 0.13 0.22 0.23 0.44 0.28 -0.28 0.16 0.20 -0.35 -0.04 0.00 -0.09 -0.27 0.32 0.11
1155 || orf19.6113 || || || Protein of unknown function; transcript detected on high-resolution tiling arrays || 1 0.99 0.21 0.14 0.50 0.09 0.05 -0.11 -0.10 0.62 -0.56 0.06 0.19 0.22 -0.34 0.53 0.15
1156 || orf19.1863 || || || Has domain(s) with predicted Rho guanyl-nucleotide exchange factor activity, role in regulation of Rho protein signal transduction and intracellular localization || 1 0.88 -0.29 0.38 0.66 0.33 0.78 0.32 0.31 1.20 -0.00 0.02 0.39 -1.25 0.97 0.08
1157 || orf19.6777 || || || Ortholog of Candida albicans WO-1 : CAWG_03032 || 1 0.64 0.00 0.36 0.96 0.39 -0.18 0.18 1.00 0.23 0.73 -0.44 0.52 -0.78 0.48 0.15
1158 || orf19.5831 || || || Ortholog of C. parapsilosis CDC317 : CPAR2_212260, C. dubliniensis CD36 : Cd36_17620, Candida orthopsilosis Co 90-125 : CORT_0A11590 and Candida tropicalis MYA-3404 : CTRG_01348 || 1 -0.03 -0.29 0.34 0.97 0.37 -0.57 -0.44 0.06 0.11 -0.24 -0.31 1.83 -0.27 0.30
1159 || orf19.763 || || || Small subunit of the heterodimeric cap binding complex; component of the spliceosomal commitment complex; Spider biofilm repressed || 1 0.06 -0.00 -0.09 0.36 0.05 0.73 -0.15 -0.19 -0.26 -0.14 -0.07 -0.09 0.30 -0.02 0.28 0.25
1160 || orf19.1106 || || || Protein with Mob2p-dependent hyphal regulation; fluconazole-induced || 1 -0.60 0.19 0.16 1.12 0.65 1.55 -0.76 -0.65 0.15 0.49 -0.02 -0.19 0.63 0.50 -0.08 -0.11
1161 || orf19.6115 || || || Dubious open reading frame || 1 -0.53 0.44 0.40 0.48 0.14 0.83 -0.37 0.06 0.21 -0.13 0.09 0.02 0.52 -0.06 0.03
1162 || orf19.444 || || || Has domain(s) with predicted nucleic acid binding, nucleotide binding activity || 1 -0.25 -0.38 0.28 -0.14 0.56 1.11 -0.41 0.56 0.07 0.06 0.69 0.24 -0.04 -0.25 0.04 -0.28
1163 || orf19.246 || || || Predicted metalloendopeptidase; Spider biofilm induced || 1 -0.37 -0.06 0.37 0.30 0.84 1.48 -0.48 -0.42 -0.25 -0.19 1.15 0.45 0.55 -0.30 0.59 0.02
1164 || orf19.7175 || HLJ1 || || Putative HSP40 co-chaperone; repressed during the mating process || 1 0.13 0.02 0.41 -0.02 0.51 0.57 -0.22 -0.05 -0.04 0.24 0.17 -0.11 0.31 -0.30 0.49 -0.45
1165 || orf19.6038 || UGA32 || || Predicted Zn(II)2Cys6 transcription factor; has similarity to S. cerevisiae Uga3, a transcription factor involved in the regulation of gamma-aminobutyrate metabolism genes; rat catheter biofilm induced || 1 0.67 0.77 0.50 0.07 0.32 0.45 0.24 0.38 0.24 -0.45 -0.30 -0.14 -0.19 -0.22 -0.24 0.12
1166 || orf19.1867 || || || Putative malate permease; induced during macrophage infection; regulated by Gcn2 and Gcn4; putative peroxisome targeting signal; Hap43-repressed; Spider biofilm induced || 1 0.83 0.99 0.69 0.27 0.78 1.40 0.73 0.54 1.19 -1.08 -0.49 -0.72 0.23 -0.86 -0.22 -0.13
1167 || orf19.6747 || || || Ortholog(s) have acid phosphatase activity, role in dephosphorylation, intracellular sterol transport and cytoplasm, nucleus localization || 1 0.56 0.65 0.81 0.06 0.61 1.55 0.14 0.28 0.59 -0.53 -0.83 -0.29 -0.66 -0.50 0.06 0.09
1168 || orf19.7356 || || || Ortholog of C. parapsilosis CDC317 : CPAR2_807080, C. dubliniensis CD36 : Cd36_85690, Candida orthopsilosis Co 90-125 : CORT_0C02090 and Candida albicans WO-1 : CAWG_02885 || 1 1.06 1.20 0.74 0.71 0.33 1.89 0.58 0.73 0.28 0.06 -0.62 -0.01 -0.12 -0.03 0.27 0.20
1169 || orf19.844 || STE11 || || Protein similar to S. cerevisiae Ste11p; mutants are sensitive to growth on H2O2 medium || 1 0.16 0.13 -0.10 -0.54 0.57 1.00 0.45 -0.01 0.94 -0.40 -1.29 -0.17 -0.00 0.47 0.52 -0.36
1170 || orf19.844 || STE11 || || Protein similar to S. cerevisiae Ste11p; mutants are sensitive to growth on H2O2 medium || 1 0.08 -0.05 -0.09 -0.36 0.61 1.15 0.22 -0.30 0.57 -0.50 -1.13 -0.56 -0.07 -0.21 0.38 -0.39
1171 || orf19.1667.1 || || || Ortholog(s) have role in mitochondrial respiratory chain complex IV assembly and mitochondrial intermembrane space, nucleus localization || 1 0.17 0.37 0.40 -0.10 1.39 2.51 0.34 0.03 0.74 -0.04 -0.61 -0.09 -0.02 -0.27 -0.09 -0.18
1172 || orf19.3310 || || || Protein of unknown function; Hap43-repressed; rat catheter and Spider biofilm induced || 1 0.09 0.24 -0.10 -0.19 1.63 1.69 0.22 0.16 0.32 -0.85 -0.86 -0.66 0.54 -0.02 1.31 -0.94
1173 || orf19.3310 || || || Protein of unknown function; Hap43-repressed; rat catheter and Spider biofilm induced || 1 -0.16 -0.04 0.40 -0.10 1.37 1.68 0.07 0.21 0.34 -0.94 -0.80 -0.56 0.16 0.16 0.80 -0.43
1174 || orf19.3310 || || || Protein of unknown function; Hap43-repressed; rat catheter and Spider biofilm induced || 1 0.13 0.22 0.36 0.15 1.30 1.60 0.13 0.06 0.20 -0.96 -0.68 -0.64 0.05 -0.03 1.04 -0.18
1175 || orf19.3310 || || || Protein of unknown function; Hap43-repressed; rat catheter and Spider biofilm induced || 1 0.47 0.52 0.36 0.17 1.75 1.91 0.44 0.49 0.57 -0.82 -0.75 -0.53 0.54 0.29 1.24 -0.37
1176 || orf19.1169 || || || Putative DnaJ-like molecular chaperone; Spider biofilm induced || 1 0.40 0.36 0.06 0.28 1.31 2.37 0.22 0.29 0.36 -0.71 -0.87 -0.54 0.02 -0.01 0.20 -0.49
1177 || orf19.1169 || || || Putative DnaJ-like molecular chaperone; Spider biofilm induced || 1 0.21 0.65 0.67 -0.09 1.30 2.55 0.45 0.22 1.02 -0.55 -0.62 -0.79 0.42 -0.01 -0.00 -0.85
1178 || orf19.1169 || || || Putative DnaJ-like molecular chaperone; Spider biofilm induced || 1 1.08 1.04 0.38 -0.18 2.07 2.66 1.06 0.74 1.08 -1.01 -1.47 -0.98 0.53 -0.27 0.60 -1.21
1179 || orf19.1169 || || || Putative DnaJ-like molecular chaperone; Spider biofilm induced || 1 0.59 0.73 0.14 -0.63 1.69 2.47 0.90 0.18 0.50 -1.05 -1.54 -1.27 0.26 -0.54 0.27 -1.03
1180 || orf19.1114 || || || Cytochrome c oxidase subunit; membrane-localized protein; rat catheter biofilm induced || 1 1.10 1.01 0.18 -0.15 1.70 1.59 1.46 0.96 0.94 -0.28 -1.20 -1.41 0.69 -0.02 0.90 -1.08
1181 || orf19.1958 || || || Dubious open reading frame || 1 0.13 0.64 0.12 -0.15 0.23 1.24 0.01 0.33 -0.04 -0.19 -0.74 -0.49 -0.57 -0.22 0.23 -0.41
1182 || orf19.6747 || || || Ortholog(s) have acid phosphatase activity, role in dephosphorylation, intracellular sterol transport and cytoplasm, nucleus localization || 1 0.50 0.34 0.19 -0.62 0.50 1.43 0.25 0.16 0.47 -0.96 -0.92 -0.70 -0.73 -0.86 0.34 -0.30
1183 || orf19.4449 || CCS1 || || Copper chaperone involved in activation and protection of superoxide dismutase Sod1p || 1 -0.05 -0.08 0.07 -0.28 0.51 0.82 0.01 -0.01 0.34 -0.33 -0.49 -0.31 -0.60 -0.34 0.14 -0.53
1184 || orf19.4449 || CCS1 || || Copper chaperone involved in activation and protection of superoxide dismutase Sod1p || 1 -0.06 -0.17 -0.15 -0.52 0.43 0.58 -0.05 -0.11 0.14 -0.49 -0.67 -0.34 -0.88 -0.48 0.11 -0.48
1185 || orf19.2818 || || || Ortholog(s) have RNA-dependent ATPase activity, second spliceosomal transesterification activity, role in generation of catalytic spliceosome for second transesterification step and U2-type catalytic step 2 spliceosome localization || 1 -0.31 -0.21 0.55 -0.19 0.31 0.59 -0.14 -0.31 0.14 -0.03 -0.29 0.24 0.04 -0.09 -0.11 0.09
1186 || orf19.4964 || || || Ortholog(s) have role in cellular bud site selection, mRNA export from nucleus, mRNA splicing, via spliceosome and RES complex localization || 1 -0.20 -0.03 0.03 -0.30 0.47 0.99 -0.31 -0.81 -0.43 0.52 -0.45 0.66 0.19 0.34 0.26 -0.34
1187 || orf19.7361 || || || Ortholog(s) have tRNA-intron endonuclease activity, role in tRNA-type intron splice site recognition and cleavage and mitochondrial outer membrane, tRNA-intron endonuclease complex localization || 1 -0.29 0.00 0.23 -0.17 0.66 0.97 -0.19 -0.90 -0.23 0.34 -0.32 0.01 0.02 0.49 0.10 -0.01
1188 || orf19.966 || DUS4 || || Ortholog(s) have tRNA dihydrouridine synthase activity, role in tRNA modification and mitochondrion localization || 1 -0.06 -0.05 -0.09 -0.30 0.54 0.99 0.00 -0.56 -0.55 0.05 -0.36 -0.43 -0.08 0.66 -0.16 -0.15
1189 || orf19.3759 || || || Putative elongator complex subunit; for modification of wobble nucleosides in tRNA; Spider biofilm induced || 1 -0.25 0.09 0.03 0.05 1.01 1.01 -0.21 -0.62 -0.64 0.54 -0.08 -0.60 0.06 0.98 0.01 -0.34
1190 || orf19.4582 || || || Ortholog(s) have role in U1 snRNA 3'-end processing, U4 snRNA 3'-end processing and U5 snRNA 3'-end processing, more || 1 -0.11 -0.17 0.17 -0.19 0.53 0.87 -0.06 -0.21 -0.11 0.31 0.04 -0.23 0.16 0.25 0.01 0.09
1191 || orf19.7280 || || || Ortholog of Candida albicans WO-1 : CAWG_02163 || 1 0.05 0.44 0.21 1.33 3.24 -0.08 -0.71 -0.14 -1.17 -1.83 0.24 0.29 0.17 0.41
1192 || orf19.515 || || || Has domain(s) with predicted nucleic acid binding, zinc ion binding activity || 1 0.19 0.27 0.62 0.37 0.60 1.38 -0.34 -0.45 -0.19 -0.09 -0.29 -0.14 0.10 0.10 0.05 0.59
1193 || orf19.5364 || || || Putative pre-mRNA splicing factor; intron in 5'-UTR; possibly an essential gene, disruptants not obtained by UAU1 method || 1 -0.08 0.34 0.67 0.28 0.84 1.50 -0.41 -0.31 0.00 0.16 -0.28 0.03 -0.04 -0.01 0.22 -0.04
1194 || orf19.7029 || || || Putative guanine deaminase; mutation confers hypersensitivity to toxic ergosterol analog; Spider biofilm induced || 1 -0.16 0.26 0.45 -0.17 0.80 1.56 -0.75 -0.90 -0.27 -0.26 -0.32 -0.20 0.46 0.16 0.58 -0.04
1195 || orf19.6134 || || || Ortholog(s) have role in ER-dependent peroxisome organization, retrograde vesicle-mediated transport, Golgi to ER and Dsl1p complex, endoplasmic reticulum membrane, nuclear envelope, peroxisome localization || 1 -0.14 0.26 0.42 0.15 0.73 0.23 -0.41 -0.40 0.10 -0.23 -0.33 0.03 0.25 -0.03 -0.19 -0.21
1196 || orf19.3906 || MRV6 || || Ortholog of Candida albicans WO-1 : CAWG_04796 || 1 -0.47 -0.59 1.06 0.29 2.42 1.09 -1.18 -0.98 0.12 -0.55 -0.73 -0.68 -0.19 -1.24 -0.61
1197 || orf19.2445 || || || Putative dicarboxylic amino acid permease; fungal-specific (no human or murine homolog); induced by alpha pheromone in SpiderM medium || 1 -0.01 0.12 0.73 0.21 1.14 1.21 -0.49 -0.47 0.46 -0.17 -0.47 -0.41 0.20 -0.20 -0.56
1198 || orf19.956 || || || Ortholog(s) have role in fermentation and mitochondrion localization || 1 -0.50 -0.35 0.60 0.17 0.98 0.98 -0.74 -0.50 -0.12 -0.16 -0.45 -0.42 -0.29 -0.16 0.03 0.03
1199 || orf19.444 || || || Has domain(s) with predicted nucleic acid binding, nucleotide binding activity || 1 -0.44 -0.25 0.21 0.04 0.26 1.01 -0.31 -0.63 -0.46 -0.23 -0.25 0.10 0.20 0.04 -0.35 -0.24
1200 || orf19.6347 || || || Pre-mRNA splicing factor; important for catalytic step II of pre-mRNA splicing; possible role in cell cycle progression; Spider biofilm induced || 1 -0.61 -0.18 0.19 0.09 0.72 1.34 -0.57 -1.06 -0.30 -0.12 -0.67 -0.19 0.01 0.09 -0.30 -0.20
1201 || orf19.3906 || MRV6 || || Ortholog of Candida albicans WO-1 : CAWG_04796 || 1 -0.58 -0.55 0.36 0.09 1.34 1.12 -1.25 -0.49 0.20 -0.38 -0.33 -0.92 0.28 -0.72 0.29
1202 || orf19.3446 || || || Ortholog(s) have Ran GTPase binding activity, role in protein import into nucleus and nucleus localization || 1 -0.25 -0.20 0.14 0.02 1.41 1.50 -1.40 -0.96 -1.06 -0.49 -0.05 -0.25 -1.27 0.12 -1.01 -0.02
1203 || orf19.2393 || || || Putative transcription factor with zinc finger DNA-binding motif || 1 -0.44 -0.33 0.59 0.28 1.04 1.56 -1.15 -1.15 -0.92 -0.69 -0.41 -0.06 -0.90 -0.49 -0.53 -0.19
1204 || orf19.6054 || || || Protein with a Bul1 domain; binds the ubiquitin ligase Rsp5 and is involved in intracellular trafficking of a general amino acid permease Gap1; repressed in an azole-resistant strain overexpressing MDR1; Spider biofilm induced || 1 0.12 -0.08 0.18 -0.46 0.75 1.08 -0.94 -1.31 -0.76 -0.24 -0.32 0.54 -0.35 -0.40 -0.18 0.35
1205 || orf19.353 || ULP1 || || SUMO deconjugation enzyme that cleaves the small ubiquitin-like modifier (SUMO) off proteins || 1 0.17 0.35 0.07 -0.40 1.03 1.12 -0.43 -0.43 -0.40 -0.21 0.04 0.19 -0.40 -0.49 -0.50 0.22
1206 || orf19.6917 || || || Putative heat shock protein with a zinc finger motif; required for protein import into mitochondria in S. cerevisiae; Spider biofilm induced || 1 0.06 -0.02 0.63 0.24 0.23 0.76 -0.23 -0.68 -0.40 -0.09 0.05 -0.25 -0.07 -0.23 -0.32 -0.60
1207 || orf19.6259 || || || Exosome non-catalytic core component; involved in 3'-5' RNA processing and degradation in the nucleus and cytoplasm; Spider biofilm induced || 1 -0.11 -0.11 0.38 -0.10 0.14 0.81 -0.17 -0.21 -0.14 0.38 -0.26 0.11 0.16 0.14 -0.05 -0.72
1208 || orf19.2804 || || || Ortholog of C. dubliniensis CD36 : Cd36_83980, C. parapsilosis CDC317 : CPAR2_102620, Candida tenuis NRRL Y-1498 : CANTEDRAFT_134550 and Debaryomyces hansenii CBS767 : DEHA2D12100g || 1 0.12 -0.42 -0.18 0.06 0.64 2.31 -0.48 -0.43 0.06 0.70 0.15 -0.13 -0.21 -0.47 0.25 -0.79
1209 || orf19.1939 || || || Ortholog of S. cerevisiae : YDR374C, C. glabrata CBS138 : CAGL0A02970g, C. dubliniensis CD36 : Cd36_51030, C. parapsilosis CDC317 : CPAR2_303320 and Candida tenuis NRRL Y-1498 : CANTEDRAFT_106457 || 1 -0.40 -0.23 -0.17 1.17 1.22 -0.62 -0.77 -0.14 0.21 0.56 -0.54 0.46 0.10 -0.70
1210 || orf19.7280 || || || Ortholog of Candida albicans WO-1 : CAWG_02163 || 1 0.04 -0.16 -0.01 0.17 1.42 1.70 -0.26 -0.35 -0.16 0.12 0.21 0.21 0.61 0.13 -0.62
1211 || orf19.4629 || || || Ortholog(s) have ubiquitin-ubiquitin ligase activity, role in mitochondrion inheritance, protein monoubiquitination, protein polyubiquitination and plasma membrane, ubiquitin ligase complex localization || 1 0.03 -0.10 -0.20 -0.71 1.09 1.05 -0.12 -0.42 0.01 0.10 -0.21 0.52 0.37 0.27 0.15 -0.62
1212 || orf19.4187 || || || Ortholog(s) have role in hyphal growth, mitochondrial genome maintenance, phospholipid transport, protein import into mitochondrial outer membrane, sporocarp development involved in sexual reproduction || 1 0.05 -0.12 0.02 -0.35 0.46 0.52 -0.14 -0.14 0.13 -0.11 -0.06 0.29 0.11 0.10 0.44 -0.30
1213 || orf19.5212 || || || Ortholog(s) have SUMO ligase activity, role in protein sumoylation, reciprocal meiotic recombination, synaptonemal complex assembly and condensed nuclear chromosome localization || 1 -0.12 -0.08 0.06 0.13 0.56 0.96 -0.11 0.05 0.42 0.14 0.03 0.23 0.08 0.02 0.48 -0.74
1214 || orf19.6499 || || || Predicted DNA-directed RNA polymerase; role in transcription; Spider biofilm induced || 1 -0.20 -0.04 -0.19 -0.46 0.89 1.21 0.01 -0.50 0.39 0.09 -0.48 0.44 0.70 0.28 0.31 0.10
1215 || orf19.6499 || || || Predicted DNA-directed RNA polymerase; role in transcription; Spider biofilm induced || 1 -0.20 -0.30 -0.19 -0.33 0.71 1.15 -0.08 -0.71 0.30 -0.16 -0.19 0.12 0.65 0.19 0.44 0.22
1216 || orf19.2580 || HST2 || || Putative histone deacetylase; role in regulation of white-opaque switch; Spider biofilm induced || 1 -0.15 -0.16 0.35 -0.01 0.41 0.48 -0.04 -0.34 0.28 -0.16 -0.20 0.02 0.43 0.03 0.35 -0.06
1217 || orf19.6273 || || || Ortholog of C. dubliniensis CD36 : Cd36_05960, C. parapsilosis CDC317 : CPAR2_301790, Candida tenuis NRRL Y-1498 : CANTEDRAFT_112420 and Debaryomyces hansenii CBS767 : DEHA2G15290g || 1 -0.60 -0.37 0.49 0.32 0.62 1.03 -0.38 -0.74 0.50 0.22 -0.30 0.20 0.23 0.40 0.28 0.00
1218 || orf19.6391 || || || Protein of unknown function; transcript upregulated in azole-resistant strain overexpressing MDR1; Spider biofilm induced || 1 -0.92 -0.47 0.10 0.22 1.01 1.18 -0.30 -0.19 0.09 -0.06 0.06 0.50 0.23 0.03 -0.24
1219 || orf19.328 || NPR2 || || Putative urea transporter; induced during infection of murine kidney, compared to growth in vitro; has murine homolog || 1 -0.34 -0.16 -0.00 -0.18 0.40 0.48 -0.26 -0.16 0.42 0.34 0.10 -0.14 0.34 0.29 0.26 0.05
1220 || orf19.1148 || || || Ortholog of C. dubliniensis CD36 : Cd36_11020 and Candida albicans WO-1 : CAWG_00266 || 1 -0.17 0.18 0.18 -0.51 1.03 0.71 -0.22 -0.21 0.66 0.02 0.20 0.10 0.55 -0.11 -0.02 -0.44
1221 || orf19.2563 || || || Ortholog(s) have U6 snRNA binding activity, role in spliceosomal complex assembly, spliceosomal tri-snRNP complex assembly and U6 snRNP localization || 1 0.46 0.64 0.16 0.04 0.90 0.94 -0.33 -0.19 -0.34 0.16 0.18 -0.15 0.83 0.26 0.28 -0.14
1222 || orf19.4662 || RLM1 || || Putative transcription factor; required for wild-type resistance to cell wall perturbation, caspofungin treatment; regulates caspofungin induction of PGA13 || 1 0.81 0.83 0.24 0.35 1.29 1.07 -0.09 -0.38 -0.42 -0.09 0.16 -0.01 1.25 0.36 0.98 -0.56
1223 || orf19.4878 || || || Protein of unknown function; Hap43-repressed; rat catheter biofilm repressed || 1 0.19 0.26 -0.03 0.01 0.22 0.40 -0.11 0.06 -0.07 -0.11 0.12 0.48 0.19 0.29 0.00 -0.25
1224 || orf19.6475 || || || Protein of unknown function; flow model biofilm induced || 1 0.92 1.46 0.31 0.40 1.52 2.99 0.18 -0.01 1.14 0.83 0.62 2.31 1.39 1.05 0.32 0.11
1225 || orf19.3966 || CRH12 || || CRH family cell wall protein; transcript regulated by Nrg1 and Tup1; alkaline induced by Rim101; repressed during cell wall regeneration; flow model biofilm induced || 1 0.24 0.46 -0.03 0.01 0.56 0.83 -0.23 -0.06 -0.13 0.16 0.39 0.38 0.05 0.28 0.03 0.03
1226 || orf19.55 || || || Ortholog(s) have role in cellular zinc ion homeostasis and endoplasmic reticulum localization || 1 0.31 0.40 -0.01 0.16 0.21 0.35 -0.25 -0.03 0.05 0.25 0.40 0.38 0.12 0.17 0.05 -0.06
1227 || orf19.748 || || || Ortholog(s) have RNA binding, nucleocytoplasmic transporter activity, structural constituent of nuclear pore activity || 1 0.36 0.83 -0.09 0.03 0.48 0.50 0.05 0.21 0.13 0.23 0.42 0.39 0.23 -0.03 0.25 0.12
1228 || orf19.6152 || || || Ortholog(s) have mitochondrion localization || 1 0.35 0.22 -0.02 -0.11 0.68 1.12 0.22 -0.08 0.20 0.23 -0.25 0.52 0.08 -0.00 0.49 0.26
1229 || orf19.416 || || || Ortholog of C. dubliniensis CD36 : Cd36_05200, C. parapsilosis CDC317 : CPAR2_107660, Candida tenuis NRRL Y-1498 : cten_CGOB_00159 and Debaryomyces hansenii CBS767 : DEHA2E07854g || 1 0.20 0.31 -0.18 0.17 1.12 1.86 0.68 -0.56 0.06 0.29 -0.28 0.61 0.22 0.13
1230 || orf19.3506 || DBR1 || || Debranchase; homozygous mutant accumulates lariat intermediates of mRNA splicing; rat catheter biofilm repressed || 1 -0.01 0.11 0.27 0.16 0.75 1.10 0.32 -0.08 0.07 0.44 -0.05 0.61 0.14 -0.09 0.19 0.42
1231 || orf19.1304 || || || Ortholog(s) have role in U4 snRNA 3'-end processing, exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA and LSU-rRNA), more || 1 0.22 0.25 0.33 -0.22 0.89 1.23 -0.03 -0.29 0.02 1.04 0.34 0.12 0.54 0.24 0.35 0.14
1232 || orf19.1286 || || || Ortholog of Candida albicans WO-1 : CAWG_04776 || 1 0.00 0.63 0.95 -0.67 1.83 2.26 0.27 -0.90 1.01 1.23 0.90 0.87 -0.44 0.44 0.25
1233 || orf19.4451 || RIA1 || || Putative translation elongation factor; genes encoding ribosomal subunits, translation factors, and tRNA synthetases are downregulated upon phagocytosis by murine macrophage || 1 0.11 0.24 0.05 -0.41 0.70 1.08 0.19 -0.10 0.38 -0.06 0.32 0.14 -0.18 -0.07 0.28 0.45
1234 || orf19.5479 || FGR12 || || Protein lacking an ortholog in S. cerevisiae; transposon mutation affects filamentous growth; flow model biofilm induced || 1 -0.85 1.09 -0.58 3.22 3.08 0.69 -0.40 0.08 0.79 0.21 0.63 0.87 1.77
1235 || orf19.5865 || || || Ortholog(s) have RNA-dependent ATPase activity, role in generation of catalytic spliceosome for first transesterification step and U2-type catalytic step 1 spliceosome localization || 1 0.23 0.67 0.54 -0.40 0.79 1.12 -0.06 -0.18 -0.48 -0.04 0.17 0.42 0.32 -0.36 0.18 0.31
1236 || orf19.6054 || || || Protein with a Bul1 domain; binds the ubiquitin ligase Rsp5 and is involved in intracellular trafficking of a general amino acid permease Gap1; repressed in an azole-resistant strain overexpressing MDR1; Spider biofilm induced || 1 0.38 0.81 0.62 -0.08 0.82 1.20 0.22 -0.02 -0.45 -0.16 0.35 0.22 0.54 -0.16 0.18 0.39
1237 || orf19.7595 || || || Has domain(s) with predicted dynactin complex localization || 1 0.42 0.58 -0.04 -0.55 0.98 1.12 0.09 -0.12 -0.14 -0.44 0.28 0.32 1.29 0.05 0.31 0.08
1238 || orf19.4439 || || || Ortholog of Candida albicans WO-1 : CAWG_00687 || 1 0.20 0.65 0.06 1.46 2.40 0.39 -0.32 -0.07 0.71 0.24 2.18 0.53 1.26
1239 || orf19.810 || || || Ortholog(s) have DNA helicase activity, role in DNA unwinding involved in DNA replication, reciprocal meiotic recombination, synapsis and nucleus localization || 1 0.57 0.83 0.44 0.03 1.69 1.61 0.13 -0.48 0.77 -0.17 0.24 0.58 0.93 -0.15 0.66 0.92
1240 || orf19.450 || || || Protein of unknown function || 1 0.05 0.74 0.02 -0.27 0.70 0.89 -0.29 -0.22 0.28 -0.14 0.15 0.16 0.53 0.09 0.16 0.78
1241 || orf19.4326 || || || Ortholog(s) have role in mRNA cis splicing, via spliceosome, maturation of 5S rRNA and U4/U6 x U5 tri-snRNP complex localization || 1 0.69 0.90 0.11 -0.43 0.92 1.18 -0.31 -0.60 -0.08 -0.10 -0.08 -0.25 0.84 -0.17 0.32 0.57
1242 || orf19.5066 || || || Putative pre-60S pre-ribosomal particle subunit; essential gene; S. cerevisiae ortholog RRP17 is essential; Hap43p-induced; rat catheter biofilm induced || 1 0.78 1.27 0.17 -0.91 1.88 1.84 0.69 0.17 0.35 1.12 0.22 0.14 1.98 0.98 0.69 0.34
1243 || orf19.4988 || || || S. cerevisiae ortholog Sae2 is an endonuclease that processes hairpin DNA structures with the MRX complex, involved in meiotic and mitotic double-strand break repair; upregulated in a cyr1 null mutant || 1 -0.04 0.45 0.03 0.03 0.89 0.94 -0.30 -0.28 -0.01 0.44 0.19 0.45 1.15 0.74 0.26 0.70
1244 || orf19.7672 || || || Ortholog(s) have role in ER-associated ubiquitin-dependent protein catabolic process, endoplasmic reticulum unfolded protein response || 1 0.10 0.13 0.38 0.43 0.49 0.52 -0.34 -0.26 0.16 0.37 -0.21 0.49 0.29 -0.07 0.68 -0.33
1245 || orf19.7412 || MUB1 || || Predicted protein required for ubiquitination; role in meiosis, regulation of cell budding in S. cereviae; Spider biofilm induced || 1 0.39 0.41 0.44 0.38 0.47 0.66 -0.40 -0.18 0.03 0.22 -0.01 0.48 0.47 -0.04 0.55 -0.12
1246 || orf19.4629 || || || Ortholog(s) have ubiquitin-ubiquitin ligase activity, role in mitochondrion inheritance, protein monoubiquitination, protein polyubiquitination and plasma membrane, ubiquitin ligase complex localization || 1 0.17 0.18 0.52 0.57 0.53 0.78 -0.07 -0.42 0.11 -0.08 -0.21 0.66 0.35 0.09 0.45 -0.08
1247 || orf19.1253 || PHO4 || || bHLH transcription factor of the myc-family; required for growth in medium lacking phosphate and for resistance to copper and Phloxine B; induced by Mnl1 under weak acid stress || 1 0.33 0.29 0.36 0.10 0.27 0.77 -0.41 -0.56 0.18 -0.16 -0.30 0.36 0.53 -0.09 0.46 -0.21
1248 || orf19.3328 || || || Putative transcription factor; S. cerevisiae ortholog Hot1 is required for the transient induction of glycerol biosynthetic genes GPD1 and GPP2 in response to high osmolarity; filament induced || 1 0.12 0.08 0.40 0.12 0.30 0.79 -0.14 -0.24 -0.01 0.11 0.01 0.44 0.79 0.24 0.59 -0.09
1249 || orf19.7032 || || || Ortholog of C. dubliniensis CD36 : Cd36_70790, C. parapsilosis CDC317 : CPAR2_301530, Candida tenuis NRRL Y-1498 : CANTEDRAFT_94947 and Debaryomyces hansenii CBS767 : DEHA2A05258g || 1 0.43 0.29 0.56 0.60 1.66 1.68 -0.34 -0.85 -0.12 -0.40 -0.87 -0.06 0.95 0.47 1.27 0.40
1250 || orf19.7032 || || || Ortholog of C. dubliniensis CD36 : Cd36_70790, C. parapsilosis CDC317 : CPAR2_301530, Candida tenuis NRRL Y-1498 : CANTEDRAFT_94947 and Debaryomyces hansenii CBS767 : DEHA2A05258g || 1 0.36 0.42 1.28 0.83 1.66 1.60 -0.44 -0.70 0.32 -0.05 -0.75 0.18 1.21 0.35 1.04 0.58
1251 || orf19.2768 || AMS1 || || Putative alpha-mannosidase; transcript regulated by Nrg1; induced during cell wall regeneration; flow model biofilm induced; Spider biofilm induced || 1 1.04 1.46 1.16 1.40 1.41 2.12 -0.12 -0.82 1.58 -0.64 -0.72 0.30 1.89 0.08 1.12 -0.41
1252 || orf19.6985 || TEA1 || || Putative transcription factor with zinc cluster DNA-binding motif; has similarity to S. cerevisiae Tea1p; Hap43p-repressed gene || 1 0.64 0.69 0.86 0.91 1.07 0.87 -0.28 -0.62 0.64 -0.48 -0.65 0.44 0.80 0.31 0.79 -0.03
1253 || orf19.4119 || SPO72 || || Protein described as similar to S. cerevisiae sporulation protein; ortholog of S. cerevisiae Atg2, an autophagic vesicle formation protein; up-regulation associated with azole resistance; Spider biofilm induced || 1 0.44 0.55 0.68 0.43 1.08 0.99 0.14 -0.46 0.67 -0.47 -0.50 0.31 0.42 0.00 0.67 0.03
1254 || orf19.4119 || SPO72 || || Protein described as similar to S. cerevisiae sporulation protein; ortholog of S. cerevisiae Atg2, an autophagic vesicle formation protein; up-regulation associated with azole resistance; Spider biofilm induced || 1 0.32 0.32 0.49 0.38 0.84 0.83 0.28 0.06 0.59 -0.46 -0.39 0.17 0.28 0.21 0.77 0.21
1255 || orf19.5506 || PLC1 || || Phosphoinositide-specific phospholipase C (PI-PLC), delta-form; essential; roles in stress resistance, hyphal growth; upregulated in biofilm; predicted N-linked glycosylation; lacks conserved EF-hand domain || 1 0.36 0.53 0.20 0.24 0.73 0.44 0.23 -0.08 0.16 -0.26 -0.46 0.20 0.16 -0.07 0.52 0.14
1256 || orf19.1339 || CPY1 || || Carboxypeptidase Y; transcript regulated at yeast-hypha transition or macrophage response; induced human neutrophils; regulated by Gcn2 and Gcn4; putative N-glycosylation || 1 0.11 0.23 0.71 0.69 0.72 0.99 -0.09 0.01 0.35 -0.70 0.12 0.08 0.96 -0.12 0.88 0.19
1257 || orf19.2408 || || || Ortholog(s) have tRNA methyltransferase activity, role in tRNA methylation, wybutosine biosynthetic process and cytosol, nucleus localization || 1 0.15 0.16 0.64 0.34 0.41 0.71 -0.10 -0.24 0.33 0.25 -0.08 0.47 0.80 -0.05 -0.08 0.37
1258 || orf19.4492 || || || Ortholog(s) have role in nuclear division, rRNA processing and mitotic spindle pole body, nuclear periphery, nucleolus, preribosome, large subunit precursor localization || 1 0.10 0.45 0.58 0.25 0.43 0.60 -0.26 -0.30 0.27 0.37 -0.12 -0.07 0.56 0.17 0.20 0.17
1259 || orf19.936 || || || Ortholog of C. dubliniensis CD36 : Cd36_50530, C. parapsilosis CDC317 : CPAR2_303990, Candida tenuis NRRL Y-1498 : CANTEDRAFT_107934 and Pichia stipitis Pignal : PICST_63283 || 1 0.25 0.81 1.71 0.25 0.93 1.34 -0.42 -0.44 0.57 0.35 0.10 0.28 0.72 0.96 -0.08 0.78
1260 || orf19.4369 || || || Ortholog of S. cerevisiae Spp41; protein involved in negative regulation of expression of spliceosome components PRP4 and PRP3 in S. cerevisiae; mutants are viable || 1 -0.04 0.08 0.67 0.24 0.67 0.99 0.01 -0.34 0.05 -0.03 -0.17 0.43 0.19 0.45 0.25 0.39
1261 || orf19.5051 || || || Has domain(s) with predicted protein heterodimerization activity || 1 0.26 0.38 0.91 0.36 1.06 1.40 0.00 -0.01 -0.15 0.32 0.11 0.98 0.48 0.79 0.21 1.13
1262 || orf19.3894 || || || Putative inositol oxygenase; mutation confers hypersensitivity to toxic ergosterol analog; Spider biofilm induced || 1 0.29 0.17 0.66 0.64 0.56 1.31 0.44 0.32 0.27 0.44 -0.50 0.62 0.38 0.49 0.34 0.34
1263 || orf19.2031 || VPS24 || || Protein similar to S. cerevisiae Vps24p, which is a member of the ESCRT III protein sorting complex; downregulated upon adherence to polystyrene || 1 0.20 0.06 0.41 0.63 1.15 1.48 0.31 -0.58 0.27 0.14 -0.74 -0.07 0.02 1.14 0.64 0.41
1264 || orf19.2031 || VPS24 || || Protein similar to S. cerevisiae Vps24p, which is a member of the ESCRT III protein sorting complex; downregulated upon adherence to polystyrene || 1 0.08 0.28 0.85 0.51 1.04 1.57 0.36 -0.59 0.49 0.25 -0.39 0.09 0.69 0.99 0.41 0.59
1265 || orf19.2031 || VPS24 || || Protein similar to S. cerevisiae Vps24p, which is a member of the ESCRT III protein sorting complex; downregulated upon adherence to polystyrene || 1 0.16 0.19 0.66 0.55 1.23 1.32 0.44 -0.59 0.62 0.17 -0.68 -0.12 0.18 0.91 0.88 0.70
1266 || orf19.2031 || VPS24 || || Protein similar to S. cerevisiae Vps24p, which is a member of the ESCRT III protein sorting complex; downregulated upon adherence to polystyrene || 1 0.39 0.42 0.79 0.67 1.45 1.45 0.74 -0.39 0.80 0.28 -0.28 -0.23 0.38 0.88 1.17 0.92
1267 || orf19.2031 || VPS24 || || Protein similar to S. cerevisiae Vps24p, which is a member of the ESCRT III protein sorting complex; downregulated upon adherence to polystyrene || 1 0.22 0.24 -0.27 0.39 1.25 1.22 0.49 -0.45 0.59 0.19 -0.37 -0.18 0.55 0.90 1.01 0.46
1268 || orf19.3019 || || || Putative DNA-dependent ATPase; transcription may be increased in an azole-resistant strain that overexpresses MDR1 || 1 -0.07 -0.06 0.17 -0.19 0.92 0.65 0.13 -0.13 0.43 0.19 -0.19 0.24 0.35 0.50 0.56 0.09
1269 || orf19.1748 || || || Protein of unknown function; shows colony morphology-related gene regulation by Ssn6 || 1 0.39 0.46 0.85 0.47 1.87 0.86 0.12 -0.40 0.36 -0.01 0.07 0.42 0.16 0.17 0.65 0.29
1270 || orf19.3203 || RCY1 || || Putative F-box protein involved in endocytic membrane traffic and/or recycling; fungal-specific (no human or murine homolog) || 1 0.19 0.30 0.50 0.65 1.35 0.30 0.08 0.15 0.49 0.25 0.28 0.32 0.41 0.20 0.14 -0.08
1271 || orf19.7568 || || || Ortholog of S. cerevisiae : SPS4, C. glabrata CBS138 : CAGL0I09834g, C. dubliniensis CD36 : Cd36_35035, C. parapsilosis CDC317 : CPAR2_200810 and Candida tenuis NRRL Y-1498 : CANTEDRAFT_112327 || 1 0.31 0.44 1.06 1.01 1.93 0.75 0.21 0.13 0.93 -0.16 -0.03 -0.36 0.98 0.24 0.21 -0.34
1272 || orf19.2565 || || || Predicted intermediate filament protein; required for nuclear and mitochondrial transmission to daughter buds in S. cerevisiae; Spider biofilm induced || 1 0.27 0.02 0.34 0.10 0.76 0.36 0.26 -0.18 0.52 -0.02 -0.21 0.17 0.22 -0.08 0.79 0.13
1273 || orf19.1933 || || || Ortholog(s) have role in peroxisome organization and peroxisomal membrane localization || 1 -0.10 0.02 0.54 -0.06 0.97 1.33 -0.15 -0.26 0.75 0.26 0.05 0.86 0.09 0.70 0.60 0.83
1274 || orf19.3701 || || || Protein of unknown function; mutants are viable; ortholog of S. cervisiae Art10, a protein of unknown function || 1 -0.03 0.05 0.01 -0.36 0.56 1.20 0.03 -0.05 0.59 0.31 0.20 0.44 0.31 1.02 0.68 0.68
1275 || orf19.873 || || || Ortholog of Candida albicans WO-1 : CAWG_04115 || 1 0.50 0.39 0.07 0.10 0.65 1.30 -0.09 0.25 0.59 0.15 0.24 0.59 -0.05 0.75 0.44 0.49
1276 || orf19.5676 || || || Ortholog(s) have cytosol, nucleus localization || 1 0.00 -0.03 -0.22 -0.11 0.47 0.63 -0.14 0.01 0.02 -0.04 0.35 0.33 0.05 0.68 0.45 0.43
1277 || orf19.3233 || HSE1 || || ESCRT-0 complex subunit; SH3-domain-containing protein || 1 0.07 0.04 -0.07 0.17 0.65 0.60 -0.22 -0.71 -0.03 -0.05 -0.14 0.32 0.46 0.28 0.64 0.99
1278 || orf19.5962 || HGT4 || || Glucose and galactose sensor; fermentation, filamentation, virulence roles; 20-member glucose transporter family; extended C terminus; high-glucose repressed; macrophage induced; flow model biofilm repressed; Spider biofilm induced || 1 -0.09 -0.04 0.15 -0.04 0.87 0.35 -0.01 -0.31 0.10 -0.07 -0.12 0.16 0.46 0.13 0.26 0.36
1279 || orf19.6913 || GCN2 || || Translation initiation factor 2-alpha (eIF2alpha) kinase; has nonessential role in amino acid starvation response, in contrast to S. cerevisiae homolog; similar to S. cerevisiae Gcn2p || 1 0.31 0.19 0.07 -0.02 0.66 0.31 0.07 0.08 0.44 0.24 -0.04 -0.14 0.10 0.30 0.12 0.15
1280 || orf19.504 || || || Ortholog(s) have ATP-dependent 3'-5' DNA helicase activity, role in nucleosome mobilization and Ino80 complex, cytosol localization || 1 -0.04 0.04 0.17 0.06 0.45 0.31 0.29 0.21 0.45 0.17 0.16 0.10 0.11 0.45 0.21 0.09
1281 || orf19.2545 || DOT6 || || Protein with a predicted role in telomeric gene silencing and filamentation; repressed by high-level peroxide stress; Spider biofilm induced || 1 0.25 0.21 0.06 0.15 0.22 0.82 0.37 -0.02 0.74 0.64 -0.15 -0.16 0.32 0.79 0.22 -0.02
1282 || orf19.5844 || || || Ortholog(s) have role in meiotic DNA recombinase assembly, reciprocal meiotic recombination and condensed nuclear chromosome localization || 1 0.68 0.29 0.40 0.22 0.31 0.66 -0.04 0.08 0.66 0.15 -0.15 0.07 0.46 0.54 -0.19 -0.37
1283 || orf19.1831 || || || Dubious open reading frame || 1 -0.07 0.31 0.48 -0.27 0.52 0.89 -0.17 -0.18 0.48 0.49 -0.06 0.22 0.50 0.17 -0.26 -0.20
1284 || orf19.2508 || PRM9 || || Protein described a similar to S. cerevisiae Prm9; not the ortholog though; mutant is viable || 1 -0.32 0.46 0.63 -0.12 0.28 0.78 0.10 0.00 0.36 0.35 -0.11 -0.16 1.14 0.32 -0.01
1285 || orf19.4757 || NAR1 || || Putative cytosolic iron-sulfur (FeS) protein assembly machinery protein; induced by nitric oxide; oxidative stress-induced via Cap1p || 1 0.13 0.17 0.38 0.19 0.48 0.77 0.32 0.09 0.48 0.43 0.16 0.28 1.14 -0.23 0.33 -0.35
1286 || orf19.4858 || VPS41 || || Protein similar to S. cerevisiae Vps41p, which is involved in vacuole organization and biogenesis; transposon mutation affects filamentous growth; regulated by Gcn4p; induced in response to amino acid starvation (3-aminotriazole treatment) || 1 0.26 0.34 0.67 0.31 0.67 0.30 0.06 -0.03 0.75 0.25 -0.18 0.03 0.91 0.09 0.34 0.00
1287 || orf19.1291 || ABZ1 || || Ortholog(s) have 4-amino-4-deoxychorismate synthase activity, role in para-aminobenzoic acid biosynthetic process and cytosol, nucleus localization || 1 0.19 0.43 0.42 -0.01 0.54 0.55 0.16 0.04 0.86 0.23 -0.09 -0.10 0.56 0.02 0.19 -0.13
1288 || orf19.217 || || || Ortholog(s) have sequence-specific DNA binding activity || 1 0.42 0.78 0.23 -0.34 1.26 0.40 0.47 -0.08 1.60 0.56 0.16 0.43 1.08 0.26 0.32 -0.93
1289 || orf19.2638 || || || Protein of unknown function; Spider biofilm induced || 1 -0.24 0.23 0.34 0.52 0.56 -0.05 0.16 0.14 1.22 0.55 0.03 0.21 0.95 0.47 -0.01 -0.19
1290 || orf19.4787 || || || Ortholog(s) have cytoplasm, nucleus localization || 1 0.41 0.32 0.19 0.09 0.28 0.21 0.30 -0.03 0.04 0.15 -0.29 0.29 0.59 0.30 0.72 -0.05
1291 || orf19.6554 || || || Regulator of calcineurin; regulated by calcineurin-Crz1 pathway; feedback regulator of calcineurin-dependent signaling; Hap43-repressed; induced by ketoconazole, hypoxia, during growth in the mouse cecum; Spider biofilm induced || 1 0.85 0.85 0.37 0.69 0.87 0.95 0.83 -0.79 -0.27 -0.59 -0.10 -0.46 0.19 0.16 1.41 -0.34
1292 || orf19.6554 || || || Regulator of calcineurin; regulated by calcineurin-Crz1 pathway; feedback regulator of calcineurin-dependent signaling; Hap43-repressed; induced by ketoconazole, hypoxia, during growth in the mouse cecum; Spider biofilm induced || 1 1.31 1.34 0.76 1.06 1.13 1.57 1.13 -0.61 -0.25 -0.38 -0.24 0.32 0.36 0.34 1.77 0.37
1293 || orf19.6525 || || || S. cerevisiae ortholog Inp1 is a peripheral membrane protein of peroxisomes involved in peroxisomal inheritance; induced by Mnl1 under weak acid stress || 1 0.54 0.43 0.12 0.22 0.53 0.28 0.13 -0.01 0.01 0.05 -0.25 0.05 0.21 0.29 0.69 -0.04
1294 || orf19.4077 || MIT1 || || Mannosylinositol phosphorylceramide (MIPC) synthase catalytic subunit; sphingolipid biosynthesis; fluconazole, caspofungin induced; macrophage-repressed; Spider biofilm induced || 1 0.60 0.94 -0.13 0.13 0.88 0.26 0.14 -0.36 -0.12 -0.07 -0.32 -0.19 0.12 0.31 0.97 0.09
1295 || orf19.4077 || MIT1 || || Mannosylinositol phosphorylceramide (MIPC) synthase catalytic subunit; sphingolipid biosynthesis; fluconazole, caspofungin induced; macrophage-repressed; Spider biofilm induced || 1 0.41 0.29 0.09 0.26 1.00 0.53 0.24 -0.11 -0.26 -0.18 -0.55 -0.16 -0.03 -0.06 1.03 0.10
1296 || orf19.4315 || || || Ortholog(s) have Rab GTPase activator activity, role in vesicle-mediated transport and intracellular localization || 1 0.43 0.61 -0.02 -0.08 0.60 0.09 0.04 0.02 -0.43 -0.60 -0.38 -0.66 0.27 -0.10 0.23 -0.15
1297 || orf19.6601.1 || YKE2 || || Possible heterohexameric Gim/prefoldin protein complex subunit; role in folding alpha-tubulin, beta-tubulin, and actin; transcript induced by yeast-to-hypha switch; regulated by Nrg1, Tup1; Spider and flow model biofilm induced || 1 1.47 1.39 0.10 0.12 2.34 1.65 0.35 -0.07 -0.85 -0.47 -0.44 -0.72 -0.00 -1.31 1.43 -0.56
1298 || orf19.4241 || || || Protein of unknown function; transcript detected on high-resolution tiling arrays || 1 0.67 0.86 -0.14 0.04 0.92 0.55 0.31 0.25 -0.21 -0.20 0.19 -0.48 0.27 -0.54 -0.04 -0.38
1299 || orf19.4863 || PDC2 || || Homeodomain-like transcription factor; regulator of pyruvate decarboxylase; contains a putative C-terminal activation domain, Glu- and Pro-rich; complements glucose utilization defect of S. cerevisiae pdc2 mutant || 1 0.30 0.07 0.10 0.18 0.59 0.56 0.15 -0.12 0.15 -0.16 -0.14 0.22 -0.29 -0.53 0.88 -0.66
1300 || orf19.238 || CCP1 || || Cytochrome-c peroxidase N terminus; Rim101, alkaline pH repressed; induced in low iron or by macrophage interaction; oxygen-induced activity; regulated by Sef1, Sfu1, and Hap43; Spider biofilm induced; rat catheter biofilm repressed || 1 1.28 0.82 1.24 0.96 1.13 2.11 -0.17 -0.40 0.08 -0.74 0.26 0.50 -2.17 -3.13 0.54 -1.12
1301 || orf19.1465 || || || Has domain(s) with predicted N-acetyltransferase activity || 1 0.42 0.07 0.38 0.65 0.50 0.70 -0.35 -0.06 -0.26 -0.10 -0.13 0.39 -0.12 -0.62 0.42 -0.39
1302 || orf19.5521 || ISA1 || || Putative mitochondrial iron-sulfur protein; alkaline repressed; induced in high iron; regulated by Sef1, Sfu1, Hap43; Spider biofilm induced || 1 0.98 1.01 0.52 0.61 1.50 1.37 0.12 -0.38 -0.52 -0.16 0.32 0.61 -0.54 -1.30 0.90 -0.13
1303 || orf19.5521 || ISA1 || || Putative mitochondrial iron-sulfur protein; alkaline repressed; induced in high iron; regulated by Sef1, Sfu1, Hap43; Spider biofilm induced || 1 1.17 1.33 0.96 1.03 1.72 1.82 0.07 -0.41 -0.20 0.28 0.56 1.17 -0.69 -1.05 0.75 -0.78
1304 || orf19.6948 || CCC1 || || Manganese transporter; required for normal filamentous growth; mRNA binds She3, localized to hyphal tips; repressed by NO, alkaline pH; colony morphology-related regulation by Ssn6; regulated by Sef1, Sfu1, Hap43; Spider biofilm induced || 1 0.59 0.62 0.47 0.71 0.90 0.58 -0.06 -0.14 -0.26 0.09 0.37 1.61 -0.25 -1.50 0.86 -0.61
1305 || orf19.6275 || || || Ortholog(s) have cytosol localization || 1 0.21 0.27 0.31 0.18 0.10 0.55 -0.09 0.00 -0.13 -0.16 0.34 0.22 0.15 -0.19 0.45 0.30
1306 || orf19.6018 || LRO1 || || Acyltransferase that catalyzes diacylglycerol esterification of phospholipids; role in lipid storage, triglyceride biosynthesis; flow model biofilm repressed || 1 0.28 0.60 0.60 0.68 0.47 0.51 -0.12 -0.03 -0.11 -0.20 0.24 0.39 0.58 0.02 0.37 0.43
1307 || orf19.2846 || || || Protein of unknown function; Hap43-repressed; induced in core caspofungin response; regulated by yeast-hypha switch; Spider biofilm repressed || 1 0.58 0.79 1.01 0.82 0.69 1.19 0.22 0.20 -0.25 -0.64 0.85 0.39 1.15 0.13 0.76 0.68
1308 || orf19.4436 || GPX3 || || Putative glutathione peroxidase involved in Cap1p-dependent oxidative stress response, required for Cap1p oxidation in response to H2O2; planktonic growth-induced || 1 0.31 0.36 0.47 0.08 0.62 0.86 0.15 0.39 -0.12 -0.81 0.55 0.14 0.61 0.15 0.46 0.46
1309 || orf19.2853 || || || Protein of unknown function; rat catheter biofilm induced || 1 -0.13 0.03 0.24 0.17 0.33 0.65 0.03 0.04 -0.14 -0.56 0.43 0.34 0.17 0.07 0.22 0.27
1310 || orf19.2846 || || || Protein of unknown function; Hap43-repressed; induced in core caspofungin response; regulated by yeast-hypha switch; Spider biofilm repressed || 1 -0.21 0.53 0.77 0.39 0.45 1.01 -0.19 -0.17 -0.47 -1.00 0.80 0.60 0.37 0.35 0.32 0.85
1311 || orf19.2846 || || || Protein of unknown function; Hap43-repressed; induced in core caspofungin response; regulated by yeast-hypha switch; Spider biofilm repressed || 1 0.23 0.67 0.87 0.47 0.54 1.09 -0.10 -0.14 -0.37 -0.82 0.78 0.47 0.68 0.06 0.39 1.01
1312 || orf19.2846 || || || Protein of unknown function; Hap43-repressed; induced in core caspofungin response; regulated by yeast-hypha switch; Spider biofilm repressed || 1 0.17 0.64 0.57 0.57 0.25 1.01 -0.19 -0.42 -0.23 -0.93 1.03 0.23 0.46 0.12 0.43 0.49
1313 || orf19.2846 || || || Protein of unknown function; Hap43-repressed; induced in core caspofungin response; regulated by yeast-hypha switch; Spider biofilm repressed || 1 0.36 0.53 0.51 0.26 0.36 0.97 -0.17 -0.62 -0.69 -1.00 0.87 0.62 0.39 0.26 0.47 0.65
1314 || orf19.2704 || || || Ortholog of Candida albicans WO-1 : CAWG_03507 || 1 0.35 0.54 0.70 0.33 0.88 0.73 0.13 -0.12 0.31 -1.26 0.56 0.37 0.59 0.20 -0.18
1315 || orf19.3362 || || || Has domain(s) with predicted flavin adenine dinucleotide binding, oxidoreductase activity and role in oxidation-reduction process || 1 0.49 0.43 0.49 0.73 0.50 0.31 -0.16 0.02 0.43 -0.98 0.18 0.46 0.60 0.62 0.15 0.92
1316 || orf19.7480 || || || Putative protein of unknown function; transcript is upregulated in clinical isolates from HIV+ patients with oral candidiasis || 1 0.20 0.37 0.64 0.46 0.28 0.00 -0.40 0.08 0.40 -0.85 0.03 0.56 0.39 -0.27 -0.41 0.85
1317 || orf19.4055 || || || Protein similar to S. cerevisiae Ybr075wp; transposon mutation affects filamentous growth; clade-associated gene expression || 1 0.00 0.27 0.16 0.15 0.35 0.03 -0.12 -0.05 0.39 -0.53 0.12 0.06 0.47 -0.37 0.06 0.22
1318 || orf19.4523 || || || Ortholog(s) have 5-formyltetrahydrofolate cyclo-ligase activity, role in folic acid-containing compound biosynthetic process and mitochondrion localization || 1 0.07 0.30 0.72 0.18 0.56 0.25 -0.35 -0.22 0.31 -0.50 -0.39 -0.08 0.54 -0.33 0.08 0.37
1319 || orf19.4942 || || || Ortholog of Candida albicans WO-1 : CAWG_00134 || 1 -0.24 -0.09 0.86 0.68 0.19 0.79 -0.10 -0.38 0.23 -0.44 0.06 0.07 0.61 -0.19 -0.32 -0.05
1320 || orf19.2395 || IME2 || || Putative serine/threonine protein kinase; mutation confers hypersensitivity to amphotericin B || 1 -0.47 0.26 0.98 -0.02 0.34 1.10 -0.16 0.02 0.94 -0.22 0.09 0.48 0.03 -0.03 -0.71 0.56
1321 || orf19.4823 || LIP6 || || Secreted lipase, member of family of lipase genes expressed differentially in response to carbon source and during infection; may have a role in nutrition and/or in creating an acidic microenvironment; induced on adherence to polystyrene || 1 0.02 0.39 0.41 -0.26 0.43 0.77 -0.16 -0.37 0.34 -0.45 0.15 0.34 0.27 -0.46 -0.41 0.83
1322 || orf19.2110 || || || Ortholog(s) have arginyltransferase activity, role in protein arginylation and cytosol, nucleus localization || 1 -0.26 -0.23 0.32 0.11 0.31 0.56 -0.00 -0.18 0.36 -0.44 0.22 0.10 0.01 -0.23 0.08 0.43
1323 || orf19.4059 || || || Ortholog(s) have role in actin cortical patch localization, arginine transport, cellular protein localization, cellular response to heat, endocytosis, late endosome to vacuole transport and lysine transport, more || 1 -0.01 0.06 0.34 0.51 0.20 0.80 -0.29 -0.25 0.29 -0.67 0.04 0.38 -0.08 -0.20 0.12 0.39
1324 || orf19.5729 || FGR17 || || Putative DNA-binding transcription factor; has zinc cluster DNA-binding motif; lacks an ortholog in S. cerevisiae; transposon mutation affects filamentous growth; Hap43p-repressed gene || 1 0.23 0.29 1.26 0.69 0.47 1.02 -0.43 -0.31 0.89 -1.09 0.20 0.52 0.16 -0.25 0.26 1.16
1325 || orf19.4911 || || || BED zinc finger protein; predicted DNA binding protein; Spider biofilm repressed || 1 0.19 0.39 0.73 0.31 0.40 0.97 -0.33 -0.45 0.12 -1.04 0.07 0.33 0.55 0.04 0.11 0.82
1326 || orf19.4353 || ULP2 || || SUMO deconjugation enzyme; removes the small ubiquitin-like modifier (SUMO) from proteins; Spider biofilm induced || 1 0.19 0.19 0.41 0.13 0.26 0.82 -0.08 -0.10 0.19 -0.53 0.10 0.30 0.04 0.03 -0.31 0.29
1327 || orf19.3935 || || || Ortholog of Candida albicans WO-1 : CAWG_04819 || 1 0.24 0.06 0.39 0.04 0.74 1.67 0.12 0.09 0.72 -0.25 0.36 0.38 0.67 -0.02 -0.16 0.30
1328 || orf19.2863.1 || ERV1 || || Predicted component of the mitochondrial intermembrane space (IMS), involved in protein import into mitochondrial intermembrane space || 1 0.11 0.25 0.55 0.16 0.56 0.79 -0.05 -0.06 0.56 -0.12 0.02 0.23 0.27 -0.32 0.05 -0.15
1329 || orf19.3881 || || || Ortholog of C. dubliniensis CD36 : Cd36_31790, C. parapsilosis CDC317 : CPAR2_204900, Candida tenuis NRRL Y-1498 : CANTEDRAFT_136864 and Debaryomyces hansenii CBS767 : DEHA2F13200g || 1 -0.06 0.03 0.64 0.04 0.78 1.23 -0.12 -0.06 0.23 -0.57 -0.08 0.04 0.28 -0.06 0.20 -0.11
1330 || orf19.2839 || CIRT4B || || Cirt family transposase; transcript repressed in an azole-resistant strain that overexpresses CDR1 and CDR2; Hap43-repressed; flow model biofilm induced || 1 -0.22 0.33 0.71 -0.08 0.98 1.33 -0.36 -0.39 0.75 -0.71 0.01 0.16 0.72 -0.49 0.17 0.54
1331 || orf19.2987 || || || Ortholog(s) have role in cellular ion homeostasis, establishment or maintenance of cell polarity, mitochondrion inheritance, regulation of cardiolipin metabolic process and mitochondrial inner membrane, nucleus localization || 1 0.08 0.31 0.35 0.05 0.54 0.81 -0.12 -0.23 0.53 -0.56 -0.46 0.04 0.46 0.04 0.09 -0.15
1332 || orf19.2394 || || || Ortholog(s) have cytoplasm, nucleus localization || 1 0.32 -0.23 0.64 1.35 0.23 1.54 0.02 0.05 0.46 -1.00 -0.37 0.38 -0.11 -0.28 -0.05 0.40
1333 || orf19.3336 || || || Ortholog of Candida albicans WO-1 : CAWG_01228 || 1 0.34 -0.38 0.63 0.03 0.14 0.54 0.57 -0.63 -0.30 0.01 -0.12 0.58
1334 || orf19.5506 || PLC1 || || Phosphoinositide-specific phospholipase C (PI-PLC), delta-form; essential; roles in stress resistance, hyphal growth; upregulated in biofilm; predicted N-linked glycosylation; lacks conserved EF-hand domain || 1 0.24 0.03 0.00 -0.05 0.79 0.45 -0.33 -0.45 0.23 -0.21 -0.62 0.36 -0.18 0.14 -0.05 0.39
1335 || orf19.130 || || || Ortholog(s) have protein serine/threonine kinase activity, ubiquitin binding activity || 1 0.12 0.29 0.22 0.11 0.57 0.33 -0.26 -0.52 0.05 -0.27 -0.41 0.10 -0.13 0.10 0.21 0.10
1336 || orf19.1513 || FAB1 || || Phosphatidylinositol 3-phosphate 5-kinase; required for hyphal growth on solid media, and for wild-type vacuolar morphology and acidification; not required for wild-type virulence in mouse systemic infection or for adherence to HeLa cells || 1 0.11 0.11 0.41 -0.07 0.56 0.41 -0.20 -0.49 0.29 -0.62 -0.39 0.16 0.06 0.26 0.08 -0.02
1337 || orf19.4270 || MNN13 || || Predicted alpha-1,3-mannosyltransferase activity with a role in protein glycosylation; regulated by Sef1p-, Sfu1p-, and Hap43p || 1 -0.09 0.14 0.16 0.22 0.36 0.53 -0.50 -0.56 0.42 -0.50 -0.64 0.05 0.53 0.34 -0.02 0.31
1338 || orf19.7205 || DUR7 || || Putative urea transporter; fungal-specific (no human or murine homolog) || 1 0.07 0.11 0.14 -0.26 0.57 0.56 -0.44 -0.60 0.30 -0.47 -0.41 0.09 0.51 -0.09 -0.49 0.27
1339 || orf19.7054 || || || Dubious open reading frame || 1 -0.02 0.25 -0.05 0.47 0.87 1.57 -0.51 -0.63 0.25 -1.17 -0.96 -0.00 0.81 0.10 -0.95 -0.11
1340 || orf19.3176 || RIM21 || || Plasma membrane pH-sensor involved in the Rim101 pH response pathway; required for processing and activation of Rim101 and for alkaline pH-induced hyphal growth; Spider biofilm induced || 1 0.01 0.32 0.15 0.10 0.62 0.41 -0.45 -0.82 0.04 -0.17 -0.49 -0.34 0.40 -0.17 -0.29 -0.04
1341 || orf19.480 || || || Protein of unknown function; rat catheter and Spider biofilm induced || 1 0.26 0.55 0.24 0.11 0.78 1.04 -0.49 -1.03 -0.57 0.01 -0.68 0.03 0.70 -0.18 -0.14 -0.05
1342 || orf19.2537 || || || Protein of unknown function; transcript detected on high-resolution tiling arrays || 1 0.10 0.56 0.38 0.20 1.25 0.64 -0.22 -0.46 -0.01 -0.66 -0.17 -0.28 0.60 -0.29 0.21 -0.14
1343 || orf19.7389 || REV3 || || Ortholog(s) have DNA-directed DNA polymerase activity, role in error-free translesion synthesis, error-prone translesion synthesis and cytosol, mitochondrion, nuclear chromatin, nucleus, zeta DNA polymerase complex localization || 1 0.25 0.46 0.09 0.22 0.59 0.49 -0.19 -0.60 0.35 -0.81 -0.10 0.10 0.49 -0.23 0.60 0.00
1344 || orf19.2768 || AMS1 || || Putative alpha-mannosidase; transcript regulated by Nrg1; induced during cell wall regeneration; flow model biofilm induced; Spider biofilm induced || 1 0.28 0.44 0.90 -0.20 1.18 1.71 -0.31 -1.70 0.32 -2.04 -1.64 -0.14 1.67 -0.43 1.13 -0.95
1345 || orf19.1513 || FAB1 || || Phosphatidylinositol 3-phosphate 5-kinase; required for hyphal growth on solid media, and for wild-type vacuolar morphology and acidification; not required for wild-type virulence in mouse systemic infection or for adherence to HeLa cells || 1 0.14 0.25 0.21 -0.16 0.56 0.27 -0.04 -0.38 0.24 -0.67 -0.12 -0.03 0.19 -0.19 0.31 -0.43
1346 || orf19.3736 || KAR4 || || Transcription factor; required for gene regulation in response to pheromones; ortholog of S. cerevisiae Kar4; role in karyogamy; opaque-specific, a-specific; induced by alpha factor || 1 -0.14 0.18 0.11 -0.06 0.55 -0.55 -0.69 0.45 -1.10 -0.59 0.23 -0.14 0.41 -0.88
1347 || CaalfMp02 || NAD6 || || Subunit 6 of NADH:ubiquinone oxidoreductase (NADH:ubiquinone dehydrogenase), a multisubunit enzyme complex (complex I) of the mitochondrial inner membrane that catalyzes the first step in mitochondrial respiration || 1 0.20 0.32 0.09 0.33 1.06 0.62 -0.43 -0.10 0.28 -0.39 -0.32 -0.22 -0.05 0.09 0.09 -0.34
1348 || CaalfMp15 || COX3B || || Subunit III of cytochrome c oxidase, which is the terminal member of the mitochondrial inner membrane electron transport chain; identical to Cox3Ap; one of three mitochondrially-encoded subunits || 1 0.15 0.12 0.09 0.45 0.61 0.79 -0.59 -0.53 -0.22 -0.64 -0.48 -0.28 0.25 0.14 0.24 -0.12
1349 || orf19.6604 || || || Ortholog of S. cerevisiae Pba1 that is involved in 20S proteasome assembly; upregulated in a cyr1 null mutant; contains a 5' UTR intron || 1 0.25 0.36 0.43 0.34 0.55 0.56 -1.19 -0.71 -0.58 -0.42 -0.82 -0.31 -0.14 0.28 0.18 -0.45
1350 || orf19.6604 || || || Ortholog of S. cerevisiae Pba1 that is involved in 20S proteasome assembly; upregulated in a cyr1 null mutant; contains a 5' UTR intron || 1 0.31 0.30 0.01 -0.22 0.72 0.72 -1.08 -0.77 -0.66 -0.52 -0.59 -0.36 -0.11 0.54 0.55 -0.30
1351 || orf19.4753 || PFK26 || || Putative 6-phosphofructo-2-kinase; protein repressed during the mating process || 1 0.02 0.11 0.79 0.04 0.60 0.81 -0.34 -0.20 -0.04 -0.84 -0.41 -0.24 0.69 0.43 0.09 0.21
1352 || orf19.4753 || PFK26 || || Putative 6-phosphofructo-2-kinase; protein repressed during the mating process || 1 0.08 0.20 0.68 0.44 0.63 0.81 -0.40 -0.44 -0.58 -1.28 -0.58 -0.54 0.86 -0.02 0.15 0.30
1353 || orf19.5634 || FRP1 || || Ferric reductase; alkaline-induced by Rim101; iron-chelation-induced by CCAAT-binding factor; fluconazole-repressed; ciclopirox-, hypoxia-, Hap43-induced; colony morphology-related regulation by Ssn6; Spider and flow model biofilm induced || 1 0.14 0.13 0.58 0.69 0.37 0.41 -0.41 -0.11 0.05 -0.83 -0.16 -0.26 0.26 0.07 0.21 0.43
1354 || orf19.2356 || CRZ2 || || C2H2 transcription factor; crz1 not crz2 null mutation suppresses fluconazole resistance of homozygous cka2 null; Rim101-repressed at pH 8; required for yeast cell adherence to silicone substrate; Spider biofilm induced || 1 0.59 0.62 0.93 1.10 0.98 1.13 -0.08 -0.61 -1.10 -2.22 0.57 -0.94 0.63 -0.30 0.70 0.12
1355 || orf19.2356 || CRZ2 || || C2H2 transcription factor; crz1 not crz2 null mutation suppresses fluconazole resistance of homozygous cka2 null; Rim101-repressed at pH 8; required for yeast cell adherence to silicone substrate; Spider biofilm induced || 1 0.42 0.37 0.75 0.99 0.91 1.21 -0.13 -0.60 -1.16 -1.84 0.58 -0.47 0.31 0.49 0.74 0.43
1356 || orf19.6440 || || || Ortholog(s) have ubiquitin-protein ligase activity, role in ubiquitin-dependent protein catabolic process and endoplasmic reticulum membrane, nuclear inner membrane localization || 1 0.08 -0.03 0.27 0.44 0.28 0.40 0.04 -0.36 0.13 -0.76 -0.14 0.04 0.14 -0.13 0.38 0.15
1357 || orf19.411 || || || Protein similar to GTPase regulators; induced in low iron; transcript activated by Mnl1 under weak acid stress; Hap43-, Sfu1- and Sef1-regulated; flow model biofilm induced, Spider biofilm induced || 1 0.06 0.42 -0.25 0.14 0.67 0.85 -0.62 -0.73 -0.23 -1.50 -0.21 -0.16 0.52 -0.01 0.07 0.51
1358 || orf19.2397.3 || || || Putative aminotransferase; Hap43-repressed; homozygous Tn insertion decreases colony wrinkling in filament-inducing conditions, does not block true hypha formation in liquid media; rat catheter and Spider biofilm induced || 1 -0.08 0.16 0.28 0.24 0.14 0.10 0.02 -0.52 -0.17 -0.75 -0.01 -0.37 0.03 -0.06 0.15 0.50
1359 || CaalfMp13 || NAD5 || || Subunit 5 of NADH:ubiquinone oxidoreductase (NADH:ubiquinone dehydrogenase), a multisubunit enzyme complex (complex I) of the mitochondrial inner membrane that catalyzes the first step in mitochondrial respiration || 1 0.54 0.52 0.61 1.03 0.39 1.49 -0.07 -0.09 -0.62 -1.03 -0.19 0.44 -0.04 -0.86 0.07 0.63
1360 || orf19.359 || GTT12 || || Ortholog(s) have glutathione peroxidase activity, glutathione transferase activity, role in glutathione metabolic process and endoplasmic reticulum, mitochondrial outer membrane, plasma membrane localization || 1 0.30 0.21 0.80 0.85 0.85 1.06 -0.32 -0.48 -0.14 -0.39 -0.55 0.33 -0.68 -0.28 0.81 -0.75
1361 || orf19.6947 || GTT11 || || Glutathione S-transferase, localized to ER; induced in exponentially growing cells, under oxidative stress; induced by nitric oxide; Spider biofilm induced || 1 -0.09 0.17 0.72 0.72 0.78 0.95 -0.26 -0.50 -0.21 -0.45 -0.65 0.38 -0.70 -0.34 0.66 -0.46
1362 || orf19.5295 || || || Protein with a predicted endonuclease/exonuclease/phosphatase family domain and a carbon catabolite repressor protein 4 domain; induced by alpha pheromone in SpiderM medium || 1 0.70 0.50 0.31 0.13 1.12 1.47 -0.02 -0.61 0.12 -0.90 -0.89 0.24 -1.08 -0.68 0.49 -0.19
1363 || orf19.5295 || || || Protein with a predicted endonuclease/exonuclease/phosphatase family domain and a carbon catabolite repressor protein 4 domain; induced by alpha pheromone in SpiderM medium || 1 0.61 0.86 0.55 0.58 0.86 0.93 0.05 -0.19 -0.22 -0.77 -0.93 0.16 -0.58 -0.96 0.39 -0.36
1364 || orf19.3161 || || || Ortholog(s) have ATPase activator activity, RNA binding activity || 1 0.55 0.70 0.12 -0.12 0.86 1.00 0.38 -0.76 -0.36 0.14 0.15 -0.45 -0.30 -0.25 0.03 0.10
1365 || orf19.1971 || TRY3 || || RING-finger transcription factor; regulator of yeast form adherence; required for yeast cell adherence to silicone substrate; Spider biofilm induced || 1 1.03 0.83 0.90 0.51 1.51 2.39 -0.36 -1.30 -1.83 -1.03 -0.16 0.04 -0.33 -0.84 -0.06 0.47
1366 || orf19.3669 || SHA3 || || Putative ser/thr kinase involved in glucose transport; Tn mutation affects filamentous growth; fluconazole-induced; ketoconazole-repressed; induced in by alpha pheromone in SpiderM; possibly essential; flow model biofilm induced || 1 0.83 1.01 0.17 0.12 2.36 2.16 -0.35 -1.57 -1.68 -1.08 -1.29 -1.26 -0.49 -0.51 0.14 0.08
1367 || orf19.3669 || SHA3 || || Putative ser/thr kinase involved in glucose transport; Tn mutation affects filamentous growth; fluconazole-induced; ketoconazole-repressed; induced in by alpha pheromone in SpiderM; possibly essential; flow model biofilm induced || 1 0.84 1.01 0.03 -0.25 2.38 2.15 -0.32 -1.52 -1.42 -0.79 -1.22 -1.37 -0.36 -0.38 0.11 -0.20
1368 || orf19.3669 || SHA3 || || Putative ser/thr kinase involved in glucose transport; Tn mutation affects filamentous growth; fluconazole-induced; ketoconazole-repressed; induced in by alpha pheromone in SpiderM; possibly essential; flow model biofilm induced || 1 1.00 1.34 0.15 -0.17 2.70 2.21 0.20 -1.13 -1.22 -0.92 -0.83 -0.79 -0.17 0.27 0.40 0.59
1369 || orf19.3669 || SHA3 || || Putative ser/thr kinase involved in glucose transport; Tn mutation affects filamentous growth; fluconazole-induced; ketoconazole-repressed; induced in by alpha pheromone in SpiderM; possibly essential; flow model biofilm induced || 1 1.24 1.44 0.29 0.05 2.82 2.30 0.18 -1.11 -1.19 -0.77 -0.82 -1.18 0.05 -0.05 0.30 0.29
1370 || orf19.3669 || SHA3 || || Putative ser/thr kinase involved in glucose transport; Tn mutation affects filamentous growth; fluconazole-induced; ketoconazole-repressed; induced in by alpha pheromone in SpiderM; possibly essential; flow model biofilm induced || 1 1.10 1.56 -0.03 -0.14 2.90 2.28 0.30 -0.88 -1.27 -0.65 -0.72 -1.00 0.04 0.09 0.47 0.10
1371 || orf19.4941 || TYE7 || || bHLH transcription factor; control of glycolysis; required for biofilm formation; hyphally regulated by Cph1, Cyr1; flucytosine, Hog1 induced; amphotericin B, caspofungin repressed; induced in flow model biofilm and planktonic cultures || 1 1.08 1.00 0.24 -0.51 1.46 1.82 -0.38 -0.70 -1.36 -0.51 -0.17 -0.44 -0.36 0.05 0.62 -0.46
1372 || orf19.4941 || TYE7 || || bHLH transcription factor; control of glycolysis; required for biofilm formation; hyphally regulated by Cph1, Cyr1; flucytosine, Hog1 induced; amphotericin B, caspofungin repressed; induced in flow model biofilm and planktonic cultures || 1 0.95 1.11 0.57 -0.28 1.54 2.02 -0.56 -1.14 -1.63 -0.55 -0.51 -0.31 -0.10 0.42 0.69 -0.42
1373 || orf19.3785 || || || DnaJ chaperone domain protein; role in pre-mRNA splicing; Spider biofilm induced || 1 0.29 0.67 0.15 -0.03 0.96 1.27 -0.58 -0.78 -0.88 -1.20 -0.27 -0.33 0.19 -0.81 0.06 -0.24
1374 || orf19.6447 || ARF1 || || ADP-ribosylation factor; probable GTPase involved in intracellular transport; one of several C. albicans ADP-ribosylation factors; N-myristoylprotein; substrate of Nmt1; Spider biofilm induced || 1 0.17 0.36 0.28 -0.41 0.82 1.06 -0.63 -0.82 -0.09 -1.01 -0.31 -0.41 -0.19 -0.78 0.10 -0.14
1375 || CaalfMp10 || NAD3 || || Subunit 3 of NADH:ubiquinone oxidoreductase (NADH:ubiquinone dehydrogenase), a multisubunit enzyme complex (complex I) of the mitochondrial inner membrane that catalyzes the first step in mitochondrial respiration || 1 0.55 0.56 0.00 0.55 0.86 0.94 -0.22 -0.34 -0.70 -0.97 -0.05 -0.30 0.39 -0.56 0.46 -0.43
1376 || orf19.6275 || || || Ortholog(s) have cytosol localization || 1 0.77 0.74 0.72 0.61 0.40 0.69 -0.19 0.01 0.04 -0.14 0.27 0.38 0.19 -0.56 0.13 0.24
1377 || orf19.2236 || FHL1 || || Fork-head transcription factor; forms a heterodimer with Ifh1 that is tethered to promoters by Tbf1; positively regulates rRNA and ribosomal protein gene transcription || 1 0.63 0.74 0.54 0.49 0.53 0.43 -0.22 0.03 -0.52 -0.37 -0.03 0.03 0.42 -0.35 0.01 -0.05
1378 || orf19.2236 || FHL1 || || Fork-head transcription factor; forms a heterodimer with Ifh1 that is tethered to promoters by Tbf1; positively regulates rRNA and ribosomal protein gene transcription || 1 0.62 0.51 0.53 0.47 0.57 0.54 -0.05 -0.05 -0.33 0.01 -0.12 0.12 0.33 0.06 0.07 -0.06
1379 || CaalfMp14 || NAD4 || || Subunit 4 of NADH:ubiquinone oxidoreductase (NADH:ubiquinone dehydrogenase), a multisubunit enzyme complex (complex I) of the mitochondrial inner membrane that catalyzes the first step in mitochondrial respiration || 1 0.55 0.47 0.12 0.52 0.61 0.82 -0.00 -0.18 -0.13 -0.39 -0.03 0.03 0.05 -0.05 -0.13 0.19
1380 || orf19.1816 || ALS3 || || Cell wall adhesin; epithelial adhesion, endothelial invasion; alleles vary in adhesiveness; immunoprotective in mice; binds SspB adhesin of S. gordonii in mixed biofilm; induced in/required for Spider biofilm; flow model biofilm repressed || 1 0.70 0.82 0.56 0.21 0.88 0.91 -0.43 -0.66 0.41 -0.78 -0.33 -0.03 0.58 0.07 0.04 0.03
1381 || orf19.6447 || ARF1 || || ADP-ribosylation factor; probable GTPase involved in intracellular transport; one of several C. albicans ADP-ribosylation factors; N-myristoylprotein; substrate of Nmt1; Spider biofilm induced || 1 0.50 0.62 0.75 0.14 1.01 1.09 -0.44 -0.58 -0.11 -0.92 -0.23 0.22 0.18 -0.19 0.24 0.50
1382 || orf19.286 || || || Has a predicted autophagy-related protein domain; transcription repressed by fluphenazine treatment || 1 0.59 0.53 1.00 0.47 0.80 1.00 -0.36 -0.46 0.40 -0.38 -0.12 0.20 0.03 -0.13 0.30 0.17
1383 || orf19.4901 || || || Predicted methyltransferase; Spider biofilm induced || 1 0.53 1.05 1.02 0.66 1.03 0.88 -0.87 -0.94 0.23 -0.68 -0.29 0.14 0.37 -0.12 0.14 0.20
1384 || orf19.3833 || || || Putative DNA-binding transcription factor; decreased transcription is observed upon fluphenazine treatment; possibly an essential gene, disruptants not obtained by UAU1 method; Hap43p-induced gene || 1 0.20 0.57 0.97 0.62 0.79 1.00 -0.61 -0.63 0.11 -0.69 -0.19 0.23 0.49 -0.49 -0.14 0.06
1385 || orf19.3301 || || || Putative ubiquitin ligase complex component; induced by heavy metal (cadmium) stress; Hog1-induced; transcript induced by Mnl1p under weak acid stress; flow model biofilm induced; Spider biofilm induced || 1 0.48 0.46 0.51 0.53 0.29 0.67 -0.02 -0.31 0.22 -0.46 0.11 0.19 0.55 -0.17 0.24 0.46
1386 || orf19.333 || FCY2 || || Purine-cytosine permease of pyrimidine salvage; mutation associated with resistance to flucytosine in clinical isolates; transposon mutation affects filamentation; farnesol-upregulated in biofilm || 1 0.74 0.51 0.97 0.56 0.95 1.15 -0.06 -0.24 0.33 -0.69 0.26 0.23 0.80 -0.26 0.27 1.00
1387 || orf19.5573 || || || Protein of unknown function; expression downregulated in an ssr1 null mutant || 1 0.90 0.57 0.94 0.91 1.49 1.45 0.20 0.09 0.44 -0.67 -0.60 0.27 0.79 0.17 0.50 0.93
1388 || orf19.7044 || RIM15 || || Ortholog(s) have protein kinase activity and role in age-dependent response to oxidative stress involved in chronological cell aging, conidiophore development, hyphal growth, protein phosphorylation, regulation of meiosis || 1 0.18 0.18 0.74 0.52 0.58 0.52 -0.05 -0.18 0.19 -0.50 -0.21 0.10 0.46 0.07 0.39 0.39
1389 || orf19.6842 || TUS1 || || Putative guanine nucleotide exchange factor; induced by Mnl1 under weak acid stress; Spider biofilm induced || 1 0.40 0.47 0.62 0.60 0.95 0.84 -0.34 -0.32 0.23 -0.58 0.26 0.25 0.28 0.46 0.36 0.73
1390 || orf19.6638 || PTC4 || || Type PP2C serine/threonine phosphatase; localized to mitochondria; mutation causes sensitivity to sodium, potassium and azole drugs; decreased expression in hyphae compared to yeast-form cells || 1 0.51 0.83 0.60 0.86 0.98 0.62 -0.33 -0.24 0.27 -0.44 0.12 0.24 0.69 0.08 0.23 0.19
1391 || orf19.7319 || SUC1 || || Zinc-finger transcription factor; regulates alpha-glucosidase exression; complements S. cerevisiae suc2 for sucrose utilization and mal13 maltase defect; required for yeast cell adherence to silicone substrate; rat catheter biofilm induced || 1 0.59 0.83 0.63 0.64 0.47 0.50 -0.23 -0.42 0.02 -0.49 -0.21 0.07 0.25 0.12 0.34 0.48
1392 || orf19.753 || MNN15 || || Putative alpha-1,3-mannosyltransferase; predicted role in protein O-linked glycosylation; Spider biofilm induced || 1 0.81 0.64 0.70 0.95 0.52 0.74 -0.05 -0.12 0.08 -0.59 -0.48 0.52 0.26 -0.14 0.69 0.47
1393 || CaalfMp13 || NAD5 || || Subunit 5 of NADH:ubiquinone oxidoreductase (NADH:ubiquinone dehydrogenase), a multisubunit enzyme complex (complex I) of the mitochondrial inner membrane that catalyzes the first step in mitochondrial respiration || 1 1.01 1.06 1.06 -0.09 -0.27 -0.25 -0.87 -0.31 0.51 0.48 -0.24 0.64 0.41
1394 || orf19.6168 || || || Ortholog of C. dubliniensis CD36 : Cd36_80830, Debaryomyces hansenii CBS767 : DEHA2F17930g, Candida tropicalis MYA-3404 : CTRG_04030 and Candida lusitaniae ATCC 42720 : CLUG_04224 || 1 0.76 0.92 0.86 0.82 0.82 1.14 0.06 -0.21 -0.11 -0.63 0.45 -0.12 0.03 -0.08 0.02 0.24
1395 || orf19.2149 || || || Putative sulfate permease; S. cerevisiae ortholog YPR003C localizes to the endoplasmic reticulum; regulated by Sef1p-, Sfu1p-, and Hap43p || 1 0.54 0.74 0.87 0.79 1.04 0.87 0.21 -0.05 0.16 -0.38 0.26 -0.03 0.04 -0.61 0.23 -0.14
1396 || orf19.3922 || || || Possible pyrimidine 5' nucleotidase; protein present in exponential and stationary growth phase yeast cultures; Hap43p-repressed gene || 1 1.06 1.19 1.74 1.05 1.38 1.61 -0.02 -0.18 0.14 -0.74 0.39 -0.18 0.47 -0.72 0.39 -0.01
1397 || orf19.5755 || || || Ortholog(s) have cyclin-dependent protein serine/threonine kinase regulator activity || 1 1.15 1.34 0.92 0.86 1.51 1.38 -0.25 -0.40 -0.21 -0.75 0.22 -0.24 0.38 -0.86 0.61 -0.17
1398 || orf19.4799 || CEF1 || || Putative mRNA splicing factor; ortholog is essential in S. cerevisiae; Spider biofilm induced || 1 0.76 0.50 0.62 0.88 1.30 1.27 -0.19 -0.57 -0.40 -0.11 0.04 -0.28 0.22 -0.02 0.53 0.12
1399 || orf19.4799 || CEF1 || || Putative mRNA splicing factor; ortholog is essential in S. cerevisiae; Spider biofilm induced || 1 0.88 0.65 0.56 1.01 1.33 0.79 -0.16 -0.51 -0.47 -0.22 -0.11 -0.49 -0.02 -0.22 0.38 0.05
1400 || orf19.7006 || || || Ortholog(s) have role in reciprocal meiotic recombination || 1 0.85 0.99 0.62 0.83 1.29 1.32 -0.40 -0.92 -0.37 -0.32 -0.26 -0.53 -0.20 -1.06 1.00 0.08
1401 || orf19.5755 || || || Ortholog(s) have cyclin-dependent protein serine/threonine kinase regulator activity || 1 1.71 1.30 1.24 1.08 1.53 1.25 -0.77 -0.94 -1.02 -1.40 -0.10 -0.40 0.04 -1.42 0.88 -0.19
1402 || orf19.775 || || || Ortholog of C. dubliniensis CD36 : Cd36_04450, C. parapsilosis CDC317 : CPAR2_105460, Debaryomyces hansenii CBS767 : DEHA2D07128g and Pichia stipitis Pignal : PICST_80203 || 1 1.27 1.24 0.85 1.12 1.05 1.02 -0.59 -0.47 -0.09 -1.24 -0.16 0.02 -0.36 -0.45 0.47 0.12
1403 || orf19.5730 || || || Putative phenylacrylic acid decarboxylase; clade-associated gene expression || 1 0.83 0.66 0.81 0.88 0.92 0.93 -0.09 -0.26 -0.14 -0.47 -0.27 0.17 -0.41 -0.15 0.57 0.32
1404 || orf19.3460 || || || Protein of unknown function; mRNA binds She3; transcript regulated upon yeast-hypha switch; induced in oralpharyngeal candidasis || 1 1.24 1.02 1.09 1.60 1.04 1.33 -0.63 -0.28 -0.45 -0.78 0.10 0.69 -0.27 -0.76 1.10 0.24
1405 || orf19.3607 || || || Ortholog of C. dubliniensis CD36 : Cd36_22860, C. parapsilosis CDC317 : CPAR2_806540, Candida tenuis NRRL Y-1498 : CANTEDRAFT_108823 and Debaryomyces hansenii CBS767 : DEHA2B13596g || 1 0.65 0.65 0.98 1.47 1.33 1.25 -0.28 -0.47 -0.59 -1.25 -0.23 0.25 0.08 -0.86 0.91 0.19
1406 || orf19.2762 || AHP1 || || Alkyl hydroperoxide reductase; immunogenic; fluconazole-induced; amphotericin B, caspofungin, alkaline repressed; core stress response induced; Ssk1/Nrg1/Tup1/Ssn6/Hog1 regulated; flow model biofilm induced; rat catheter biofilm repressed || 1 1.19 1.12 1.39 1.17 -0.65 -0.97 -0.64 -2.19 -0.55 0.18 0.39 -1.08 0.63 0.27
1407 || orf19.775 || || || Ortholog of C. dubliniensis CD36 : Cd36_04450, C. parapsilosis CDC317 : CPAR2_105460, Debaryomyces hansenii CBS767 : DEHA2D07128g and Pichia stipitis Pignal : PICST_80203 || 1 0.91 0.72 0.86 0.88 0.89 1.06 -0.90 -0.92 -0.31 -1.40 -0.49 -0.12 -0.41 -0.79 0.35 0.34
1408 || orf19.4921 || || || Ortholog of C. dubliniensis CD36 : Cd36_12030 and Candida albicans WO-1 : CAWG_00152 || 1 0.40 0.25 0.86 0.88 0.63 0.71 -0.54 -0.44 -0.24 -0.69 -0.25 -0.15 -0.26 -0.39 0.21 0.31
1409 || orf19.3355 || ISN1 || || Putative inosine 5'-monophosphate 5'-nucleotidase; fungal-specific (no human or murine homolog) || 1 0.72 0.67 0.86 0.86 0.36 1.03 -0.58 -0.21 -0.22 -0.80 -0.10 -0.03 -0.46 -0.08 -0.00 0.68
1410 || orf19.1808 || MED5 || || RNA polymerase II mediator complex subunit; transcription positively regulated by Tbf1p || 1 0.43 0.17 0.69 1.31 0.59 0.88 -0.10 -0.84 0.02 -0.46 -0.29 -0.06 0.27 -0.38 0.95 0.06
1411 || orf19.6763 || SLK19 || || Alkaline-induced protein of plasma membrane; affects cell aggregation, cell wall; similar to S. cerevisiae Slk19p (a kinetochore protein with roles in mitosis, meiosis); required for wild-type virulence in mouse; macrophage-downregulated || 1 0.25 0.31 0.27 0.19 0.32 0.65 -0.10 -0.24 -0.21 -0.67 0.05 0.34 0.51 -0.25 0.76 -0.07
1412 || orf19.3460 || || || Protein of unknown function; mRNA binds She3; transcript regulated upon yeast-hypha switch; induced in oralpharyngeal candidasis || 1 0.80 0.57 0.76 0.79 0.41 1.21 -0.82 -0.84 -0.42 -1.14 0.46 0.56 0.38 -1.98 1.67 0.50
1413 || orf19.3460 || || || Protein of unknown function; mRNA binds She3; transcript regulated upon yeast-hypha switch; induced in oralpharyngeal candidasis || 1 0.95 0.74 0.88 1.41 1.11 1.23 -0.61 -0.34 -0.74 -1.04 0.23 0.81 0.46 -2.21 1.61 0.28
1414 || orf19.3460 || || || Protein of unknown function; mRNA binds She3; transcript regulated upon yeast-hypha switch; induced in oralpharyngeal candidasis || 1 0.89 0.84 1.12 1.44 1.09 1.49 -0.58 -0.65 -0.69 -1.11 0.25 1.16 0.35 -1.68 2.21 0.69
1415 || orf19.3460 || || || Protein of unknown function; mRNA binds She3; transcript regulated upon yeast-hypha switch; induced in oralpharyngeal candidasis || 1 0.44 0.75 0.60 1.31 1.07 1.26 -0.59 -0.67 -0.55 -1.17 0.34 0.46 -0.32 -1.54 1.40 0.50
1416 || orf19.4951 || || || Protein of unknown function; Spider biofilm induced || 1 0.26 0.19 -0.13 0.22 0.41 1.13 -0.03 -0.94 -0.65 -0.79 0.38 0.03 -0.05 -0.19 0.97 0.28
1417 || orf19.4951 || || || Protein of unknown function; Spider biofilm induced || 1 0.26 0.28 0.15 0.59 0.45 1.28 0.01 -0.67 -0.99 -0.81 0.50 -0.09 0.15 -0.52 0.84 0.01
1418 || orf19.480 || || || Protein of unknown function; rat catheter and Spider biofilm induced || 1 0.70 0.37 0.47 0.22 0.87 0.83 0.18 0.04 -0.52 0.23 -0.10 0.15 0.24 -0.10 0.92 0.19
1419 || orf19.4133 || || || Protein wth a predicted role in transcription from RNA polymerase II promoters; Spider biofilm induced || 1 0.35 0.37 0.47 -0.13 1.21 1.47 -0.04 -0.08 -0.31 0.04 -0.48 0.41 0.16 -0.09 0.89 0.20
1420 || orf19.4133 || || || Protein wth a predicted role in transcription from RNA polymerase II promoters; Spider biofilm induced || 1 0.61 0.54 0.64 0.10 1.33 1.79 0.03 -0.06 -0.25 0.44 -0.17 0.65 0.10 0.10 0.90 0.57
1421 || orf19.7574 || || || Ortholog(s) have ubiquitin ligase complex localization || 1 0.31 0.29 0.43 0.39 1.25 1.35 -0.02 0.22 0.16 0.06 -0.10 0.34 0.07 0.03 0.68 0.11
1422 || orf19.5833 || || || Ortholog(s) have polyubiquitin binding activity || 1 0.33 0.52 0.30 0.18 0.89 1.06 -0.28 -0.27 0.11 0.25 0.13 0.40 -0.12 0.05 0.81 0.48
1423 || orf19.5961 || || || Ortholog(s) have role in proteasome regulatory particle assembly, proteolysis and cytosol, nucleus, proteasome regulatory particle localization || 1 0.61 0.79 0.62 0.44 1.42 1.62 -0.32 -0.15 -0.06 -0.52 0.16 -0.03 0.21 0.27 1.36 0.74
1424 || orf19.7342 || AXL1 || || Putative endoprotease; induced by alpha factor; transcript is upregulated in an RHE model of oral candidiasis and in clinical isolates from HIV+ patients with oral candidiasis || 1 0.66 0.79 0.35 0.20 1.74 1.96 0.05 -0.20 -0.28 -0.68 -0.15 0.02 0.72 0.35 1.36 0.35
1425 || orf19.7078 || || || Ortholog(s) have role in meiosis and cytoplasm localization || 1 0.19 0.09 0.26 0.06 1.33 1.47 -0.53 -0.22 -0.53 -0.80 0.24 -0.29 -0.27 -0.10 0.95 0.17
1426 || orf19.4953 || || || Putative ATPase; predicted role in ER-associated protein catabolism; induced during chlamydospore formation in both C. albicans and C. dubliniensis; rat catheter biofilm repressed || 1 0.90 0.65 0.30 0.30 1.29 1.41 -0.14 -0.57 -0.22 -0.89 0.05 -0.01 -0.41 -0.23 1.13 0.14
1427 || orf19.7085 || || || Protein of unknown function; induced in core stress response; induced by cadmium stress via Hog1; oxidative stress-induced via Cap1; induced by Mnl1 under weak acid stress; macrophage-repressed; rat catheter and Spider biofilm induced || 1 1.38 1.42 0.69 -0.47 2.61 2.90 -0.65 -0.73 -1.79 -1.89 0.54 0.03 -0.10 -1.02 1.95 -0.08
1428 || orf19.7085 || || || Protein of unknown function; induced in core stress response; induced by cadmium stress via Hog1; oxidative stress-induced via Cap1; induced by Mnl1 under weak acid stress; macrophage-repressed; rat catheter and Spider biofilm induced || 1 1.64 1.67 1.03 -0.16 2.85 3.03 -0.64 -0.57 -1.62 -1.80 0.72 0.21 0.05 -0.69 2.09 -0.16
1429 || orf19.7085 || || || Protein of unknown function; induced in core stress response; induced by cadmium stress via Hog1; oxidative stress-induced via Cap1; induced by Mnl1 under weak acid stress; macrophage-repressed; rat catheter and Spider biofilm induced || 1 1.51 1.64 1.07 -0.14 2.90 2.97 -0.47 -0.37 -1.43 -1.61 0.70 0.30 0.06 -0.47 2.13 0.10
1430 || orf19.7085 || || || Protein of unknown function; induced in core stress response; induced by cadmium stress via Hog1; oxidative stress-induced via Cap1; induced by Mnl1 under weak acid stress; macrophage-repressed; rat catheter and Spider biofilm induced || 1 1.50 1.69 1.23 0.01 2.80 3.13 -0.39 -0.56 -1.66 -1.63 0.69 0.12 0.16 -0.69 1.89 0.17
1431 || orf19.7085 || || || Protein of unknown function; induced in core stress response; induced by cadmium stress via Hog1; oxidative stress-induced via Cap1; induced by Mnl1 under weak acid stress; macrophage-repressed; rat catheter and Spider biofilm induced || 1 1.89 2.04 1.19 0.05 3.22 3.45 -0.09 -0.12 -1.37 -1.49 1.10 0.38 0.46 -0.38 2.39 0.15
1432 || orf19.4657 || || || Ortholog(s) have phosphoprotein phosphatase activity, role in negative regulation of phospholipid biosynthetic process, nuclear envelope organization and Nem1-Spo7 phosphatase complex, integral to membrane, mitochondrion localization || 1 0.80 1.09 0.19 0.57 2.30 2.01 -0.00 -0.94 -1.24 -0.77 0.76 0.35 -0.26 -0.64 0.95 0.26
1433 || orf19.2392 || || || Ortholog of C. dubliniensis CD36 : Cd36_28460, Debaryomyces hansenii CBS767 : DEHA2B00704g, Pichia stipitis Pignal : PICST_43964 and Spathaspora passalidarum NRRL Y-27907 : spas_CGOB_00057 || 1 0.43 0.51 0.61 0.30 2.20 1.95 -0.35 -0.37 -0.89 -0.36 0.69 0.22 -0.23 -0.04 0.71 0.22
1434 || orf19.2392 || || || Ortholog of C. dubliniensis CD36 : Cd36_28460, Debaryomyces hansenii CBS767 : DEHA2B00704g, Pichia stipitis Pignal : PICST_43964 and Spathaspora passalidarum NRRL Y-27907 : spas_CGOB_00057 || 1 0.40 0.52 0.31 -0.09 2.31 2.03 -0.26 -0.36 -0.54 -0.23 0.68 0.13 0.16 0.37 0.79 0.21
1435 || orf19.2721 || || || Ortholog(s) have role in ascospore formation, regulation of mitotic cell cycle, regulation of translation and cytosol, nucleus localization || 1 0.41 0.54 0.46 0.13 0.81 1.15 0.02 -0.05 -0.62 -0.11 0.55 0.53 -0.06 -0.30 0.37 -0.13
1436 || orf19.7227 || || || Protein phosphatase inhibitor; Hap43-repressed; homozygous Tn insertion decreases colony wrinkling but does not block hyphal growth in liquid media; mutation confers hypersensitivity to toxic ergosterol analog; Spider biofilm induced || 1 0.56 0.98 0.39 -0.26 2.64 2.53 0.16 0.13 -0.54 -1.37 0.83 -0.62 -0.06 -0.28 1.27 1.53
1437 || orf19.699 || || || Protein of unknown function; flow model, rat catheter, Spider biofilm induced || 1 0.32 0.70 0.62 0.64 1.60 2.18 0.17 -0.32 -0.54 -1.06 -0.01 -0.63 0.71 -0.86 0.98 0.12
1438 || CaalfMp10 || NAD3 || || Subunit 3 of NADH:ubiquinone oxidoreductase (NADH:ubiquinone dehydrogenase), a multisubunit enzyme complex (complex I) of the mitochondrial inner membrane that catalyzes the first step in mitochondrial respiration || 1 0.47 0.53 0.37 0.65 1.20 1.51 0.21 0.05 -0.82 -0.84 0.02 0.77 0.17 -0.58 0.79 0.70
1439 || orf19.6596 || || || Putative esterase; possibly transcriptionally regulated by Tac1; induced by Mnl1 under weak acid stress; protein present in exponential and stationary growth phase yeast cultures; Spider biofilm repressed || 1 -0.07 0.18 0.32 0.22 0.47 0.65 -0.43 -0.33 -0.22 -0.82 -0.09 0.27 0.04 0.11 0.38 0.12
1440 || orf19.3607 || || || Ortholog of C. dubliniensis CD36 : Cd36_22860, C. parapsilosis CDC317 : CPAR2_806540, Candida tenuis NRRL Y-1498 : CANTEDRAFT_108823 and Debaryomyces hansenii CBS767 : DEHA2B13596g || 1 0.86 0.72 1.18 1.03 1.51 1.65 -1.16 -1.18 -0.55 -1.25 -0.34 0.77 0.24 -0.14 1.58 0.43
1441 || orf19.6817 || FCR1 || || Transcription factor; repressor of fluconazole/ketoconazole/brefeldin A resistance; Tn mutation enhances filamentation; partially rescues S. cerevisiae pdr1 pdr3 fluconazole sensitivity; rat catheter biofilm induced/Spider biofilm repressed || 1 0.37 0.24 1.32 0.49 0.95 1.78 -0.96 -1.04 -0.09 -1.74 0.13 0.17 0.18 -0.78 1.23 0.81
1442 || orf19.5749 || SBA1 || || Similar to co-chaperones; induced in high iron; farnesol-, heavy metal (cadmium) stress-induced; protein level decreases in stationary phase cultures; Hap43-repressed || 1 -0.10 -0.07 0.04 -0.22 0.74 1.26 -0.41 -0.42 -0.03 -0.57 -0.06 0.32 0.04 -0.31 0.67 0.03
1443 || orf19.2341 || HNT1 || || Protein with similarity to protein kinase C inhibitor-I; protein level decreases in stationary phase cultures || 1 -0.07 -0.07 0.37 0.06 1.28 1.56 -0.01 -0.39 -0.05 -0.56 -0.23 0.24 0.21 -0.63 1.17 -0.02
1444 || orf19.1075 || || || Protein of unknown function; Spider biofilm induced || 1 -0.11 -0.04 0.38 0.19 1.58 2.18 -0.27 -0.77 -0.17 -0.83 0.03 0.61 0.79 -0.87 1.50 -0.61
1445 || orf19.7027 || || || Protein of unknown function; Spider biofilm induced || 1 -0.28 -0.11 0.61 0.11 1.90 1.93 -0.56 -0.86 0.06 -1.27 -0.37 -0.42 0.26 -1.00 0.68 -0.30
1446 || orf19.2769 || || || Putative protease B inhibitor; hyphal-induced expression; Cyr1p- and Ras1p-repressed || 1 0.39 0.50 0.69 0.23 1.67 2.10 -0.61 -0.98 -0.70 -1.53 -0.51 -0.08 0.19 -1.13 1.25 -0.40
1447 || orf19.2769 || || || Putative protease B inhibitor; hyphal-induced expression; Cyr1p- and Ras1p-repressed || 1 0.52 0.62 0.64 0.36 1.84 2.12 -0.63 -1.18 -0.75 -1.54 -0.56 -0.00 0.17 -1.20 1.35 -0.67
1448 || orf19.2769 || || || Putative protease B inhibitor; hyphal-induced expression; Cyr1p- and Ras1p-repressed || 1 0.52 0.49 0.47 0.33 1.71 2.01 -0.64 -0.97 -0.44 -1.48 -0.51 -0.00 0.31 -1.20 1.18 -0.57
1449 || orf19.2769 || || || Putative protease B inhibitor; hyphal-induced expression; Cyr1p- and Ras1p-repressed || 1 0.52 0.59 0.94 0.45 1.82 2.17 -0.55 -0.93 -0.52 -1.35 -0.56 0.15 0.17 -1.31 1.19 -0.75
1450 || orf19.2769 || || || Putative protease B inhibitor; hyphal-induced expression; Cyr1p- and Ras1p-repressed || 1 0.65 0.66 1.11 0.58 1.81 2.03 -0.45 -0.92 -0.63 -1.44 -0.41 -0.03 0.08 -1.15 1.31 -0.57
1451 || orf19.7106 || VPS70 || || Ortholog(s) have role in protein targeting to vacuole and endoplasmic reticulum localization || 1 0.09 0.06 0.11 0.19 0.47 0.52 -0.31 -0.28 -0.24 -0.47 -0.12 0.07 0.00 -0.26 0.85 -0.20
1452 || orf19.3932 || || || Predicted RNA binding protein; stationary phase enriched; induced in core caspofungin response; induced by nitric oxide independent of Yhb1; repressed in ssr1 null; ketoconazole, hypoxia induced; Spider biofilm induced || 1 -0.23 -0.18 0.10 -0.17 2.14 2.42 -1.60 -2.17 -1.19 -1.92 -0.93 0.21 0.34 -0.31 2.65 -0.41
1453 || orf19.3932 || || || Predicted RNA binding protein; stationary phase enriched; induced in core caspofungin response; induced by nitric oxide independent of Yhb1; repressed in ssr1 null; ketoconazole, hypoxia induced; Spider biofilm induced || 1 -0.04 -0.04 0.35 0.16 2.28 2.62 -1.43 -1.92 -0.83 -2.02 -0.64 -0.15 0.56 -0.72 2.66 -0.69
1454 || orf19.5601 || || || Ortholog(s) have extracellular region localization || 1 -0.03 -0.09 0.19 0.15 1.08 -0.93 -1.08 -0.61 -0.77 -0.71 -0.21 0.06 -0.84 1.38 -0.38
1455 || orf19.5125 || || || Protein of unknown function; induced by ketoconazole; Spider, F-12/CO2 and flow model biofilm induced || 1 0.14 -0.08 0.88 0.33 0.95 0.98 -0.30 -0.62 -0.28 -1.03 -1.03 -0.06 -0.10 -0.78 1.32 -0.27
1456 || orf19.4043 || || || Protein with a predicted pleckstrin homology domain; induced by alpha pheromone in SpiderM medium || 1 0.36 0.36 0.71 0.50 1.33 0.84 -0.49 -0.41 -0.59 -0.67 -0.04 -0.28 -0.61 -0.52 0.40 -0.21
1457 || orf19.7159 || || || Putative protein of unknown function; Hap43p-repressed gene; ortholog of S. cerevisiae YMR185W || 1 0.25 0.13 0.46 0.22 0.60 0.80 -0.40 -0.18 -0.24 -0.25 -0.13 -0.09 -0.42 -0.45 0.27 0.14
1458 || orf19.3441 || FRP6 || || Putative ammonia transport protein; regulated by Nrg1 and Tup1; regulated by Ssn6; induced by human neutrophils || 1 0.36 0.32 0.46 -0.24 1.47 1.86 -0.83 -0.88 -0.26 -1.52 -0.08 -0.08 0.08 -1.47 0.14 0.71
1459 || orf19.1285 || || || Plasma membrane-localized protein of unknown function; Hap43p-repressed gene || 1 0.05 0.04 0.19 -0.25 1.63 1.78 -0.50 -0.88 -0.17 -1.03 -0.09 -0.03 -0.25 -0.93 1.00 0.25
1460 || orf19.1285 || || || Plasma membrane-localized protein of unknown function; Hap43p-repressed gene || 1 0.19 0.17 0.31 0.13 1.75 2.14 -0.35 -0.82 -0.41 -1.11 -0.12 0.17 -0.36 -1.22 0.96 0.73
1461 || orf19.3441 || FRP6 || || Putative ammonia transport protein; regulated by Nrg1 and Tup1; regulated by Ssn6; induced by human neutrophils || 1 -0.00 -0.23 0.10 -0.56 1.52 1.85 -0.54 -0.63 -0.75 -1.37 -0.15 -0.00 -0.81 -1.61 0.70 0.71
1462 || orf19.7436 || AAF1 || || Possible regulatory protein; possible adhesin-like; Glu-rich domain; production in S. cerevisiae increases endothelial cell adherence and flocculence; flow model biofilm, alkaline or caspofungin induced || 1 -0.42 -0.23 0.72 -0.14 1.58 1.94 -0.03 -0.51 -0.00 -1.45 0.37 0.57 0.07 -1.15 1.09 0.77
1463 || orf19.7570 || UGA3 || || Zn(II)2Cys6 transcription factor; required for utilization of gamma-aminobutyrate (GABA) as a nitrogen source; mutants display decreased CFU in mouse kidneys; Spider biofilm induced || 1 -0.03 -0.35 0.35 0.17 0.93 1.33 -0.71 -0.45 -0.22 -1.08 0.17 0.47 -0.08 -0.77 1.00 1.00
1464 || orf19.5770 || OPT8 || || Oligopeptide transporter; similar to Opt1 and to S. cerevisiae Ygl114wp, but not other OPTs; induced by nitric oxide, amphotericin B; expression of OPT6, 7, 8 does not complement mutants lacking Opt1, Opt2, and Opt3; Spider biofilm induced || 1 -0.11 -0.02 0.57 0.34 0.87 1.54 -0.30 -0.70 0.13 -0.46 -0.15 0.36 -0.30 -0.75 0.52 0.41
1465 || orf19.285 || || || Ortholog of S. cerevisiae Igo2; role in mRNA stabilization of mRNA; Spider biofilm induced || 1 0.18 0.18 0.48 0.05 1.04 1.33 -0.18 -0.44 0.02 -0.68 0.23 0.48 -0.32 -0.13 0.50 0.59
1466 || orf19.285 || || || Ortholog of S. cerevisiae Igo2; role in mRNA stabilization of mRNA; Spider biofilm induced || 1 0.10 0.01 0.22 -0.20 0.82 1.03 -0.44 -0.53 0.18 -0.52 0.05 0.39 -0.47 -0.02 0.29 0.45
1467 || orf19.1777 || || || Ortholog(s) have ubiquitin-specific protease activity, role in endocytosis, protein deubiquitination and cell division site, cytosol, nucleus, peroxisome, transport vesicle localization || 1 0.26 0.28 0.07 0.04 0.99 1.02 -0.53 -0.33 0.08 -0.10 -0.07 0.36 -0.35 -0.28 0.63 0.38
1468 || orf19.1777 || || || Ortholog(s) have ubiquitin-specific protease activity, role in endocytosis, protein deubiquitination and cell division site, cytosol, nucleus, peroxisome, transport vesicle localization || 1 -0.07 0.07 0.02 0.01 0.96 1.06 -0.45 -0.74 0.21 -0.18 -0.13 0.40 -0.18 -0.30 0.68 0.06
1469 || orf19.771 || LPG20 || || Aldo-keto reductase family protein; similar to aryl alcohol dehydrogenases; osmotic stress-induced, correlates with overexpression of MDR1 in fluconazole-resistant isolate; stationary phase enriched protein || 1 0.16 0.17 0.55 0.29 1.60 1.30 -0.12 -0.43 0.17 -1.04 -0.07 0.38 -0.23 -0.18 0.53 0.28
1470 || orf19.771 || LPG20 || || Aldo-keto reductase family protein; similar to aryl alcohol dehydrogenases; osmotic stress-induced, correlates with overexpression of MDR1 in fluconazole-resistant isolate; stationary phase enriched protein || 1 0.21 0.18 0.43 0.34 1.64 1.33 -0.20 -0.33 0.02 -0.88 -0.17 0.25 -0.46 -0.40 0.32 -0.23
1471 || orf19.5102 || PLB5 || || Putative GPI-linked phospholipase B, fungal-specific (no mammalian homolog); null mutation eliminates cell-associated phospholipase A2 activity and attenuates virulence; fluconazole-repressed; flow model biofilm repressed || 1 -0.01 0.27 0.49 0.73 0.75 1.27 -0.37 -0.52 -0.43 -0.69 0.05 0.33 -0.14 -0.53 0.61 0.39
1472 || orf19.4044 || MUM2 || || Protein similar to S. cerevisiae Mum2, a protein essential for meiotic DNA replication and sporulation; induced by alpha pheromone in SpiderM medium; transcript regulated by Tup1 || 1 0.48 0.67 1.09 0.53 1.30 1.06 -0.68 -0.64 -1.04 -0.68 0.61 0.56 -0.89 -1.47 1.02 0.43
1473 || orf19.3292 || || || Ortholog(s) have peptide-methionine (R)-S-oxide reductase activity, role in cellular response to oxidative stress and cytosol, mitochondrion, nucleus localization || 1 0.53 0.56 -0.01 0.09 1.45 1.41 -0.78 -0.90 -0.75 -0.33 0.41 0.75 -0.85 -1.11 1.42 0.78
1474 || orf19.3292 || || || Ortholog(s) have peptide-methionine (R)-S-oxide reductase activity, role in cellular response to oxidative stress and cytosol, mitochondrion, nucleus localization || 1 0.14 0.50 0.14 0.59 1.15 1.35 -0.75 -0.80 -0.78 -0.71 0.21 0.64 -0.80 -1.00 1.20 0.81
1475 || orf19.4043 || || || Protein with a predicted pleckstrin homology domain; induced by alpha pheromone in SpiderM medium || 1 0.29 0.51 0.57 0.47 1.44 1.04 -0.26 -0.26 -0.93 -0.82 0.13 -0.04 -0.41 -0.51 0.76 0.62
1476 || orf19.607 || || || Protein involved in transcription-coupled nucleotide excision repair of UV-induced DNA lesions; Spider biofilm induced || 1 0.27 0.37 0.05 0.03 1.07 0.95 -0.40 -0.25 -0.85 -0.69 -0.03 0.19 -0.22 -0.82 0.72 0.64
1477 || orf19.4657 || || || Ortholog(s) have phosphoprotein phosphatase activity, role in negative regulation of phospholipid biosynthetic process, nuclear envelope organization and Nem1-Spo7 phosphatase complex, integral to membrane, mitochondrion localization || 1 0.41 0.41 0.14 0.26 1.48 1.52 -0.39 -1.17 -1.52 -1.20 0.40 0.32 -0.91 -0.90 0.63 0.42
1478 || orf19.4657 || || || Ortholog(s) have phosphoprotein phosphatase activity, role in negative regulation of phospholipid biosynthetic process, nuclear envelope organization and Nem1-Spo7 phosphatase complex, integral to membrane, mitochondrion localization || 1 0.38 0.51 0.03 0.56 1.50 1.73 -0.30 -1.34 -1.31 -0.99 0.28 0.17 -0.88 -1.20 0.68 0.29
1479 || orf19.398 || || || Ortholog of C. dubliniensis CD36 : Cd36_08040, C. parapsilosis CDC317 : CPAR2_207180, Candida tenuis NRRL Y-1498 : CANTEDRAFT_114140 and Debaryomyces hansenii CBS767 : DEHA2G13992g || 1 1.02 0.94 0.40 0.79 2.17 2.65 -0.68 -1.33 -1.14 -1.57 -0.10 0.52 -0.85 -1.55 0.95 0.04
1480 || orf19.398 || || || Ortholog of C. dubliniensis CD36 : Cd36_08040, C. parapsilosis CDC317 : CPAR2_207180, Candida tenuis NRRL Y-1498 : CANTEDRAFT_114140 and Debaryomyces hansenii CBS767 : DEHA2G13992g || 1 0.37 0.66 -0.06 0.22 1.73 2.08 -0.80 -1.37 -1.26 -1.50 -0.44 0.05 -0.84 -1.75 0.32 0.18
1481 || orf19.2898 || || || Ortholog(s) have borate efflux transmembrane transporter activity, role in borate transport, protein targeting to vacuole and fungal-type vacuole, plasma membrane localization || 1 0.13 0.70 0.15 0.57 0.63 1.55 -0.66 -0.53 -1.82 -1.10 0.36 0.47 -0.44 -1.38 0.71 0.23
1482 || orf19.6817 || FCR1 || || Transcription factor; repressor of fluconazole/ketoconazole/brefeldin A resistance; Tn mutation enhances filamentation; partially rescues S. cerevisiae pdr1 pdr3 fluconazole sensitivity; rat catheter biofilm induced/Spider biofilm repressed || 1 -0.08 -0.38 0.21 0.76 0.97 1.90 -0.18 -0.75 -0.61 -2.10 0.09 0.21 -0.65 -1.33 1.13 0.41
1483 || orf19.5605 || || || Ortholog(s) have protein binding, bridging, ubiquitin protein ligase binding activity and role in positive regulation of ubiquitin-dependent endocytosis, regulation of intracellular transport || 1 0.28 -0.27 0.13 0.28 0.62 0.95 0.12 -0.62 -0.09 -0.93 0.16 -0.24 0.12 -0.57 0.83 0.38
1484 || orf19.3845 || FGR3 || || Protein lacking an ortholog in S. cerevisiae; transposon mutation affects filamentous growth || 1 -0.01 0.29 0.65 0.47 0.89 1.28 -0.34 -0.37 0.36 -0.25 0.13 -0.00 -0.13 -0.34 0.98 0.48
1485 || orf19.1481 || HAP42 || || Predicted transcription factor; possibly an essential gene, disruptants not obtained by UAU1 method || 1 -0.33 -0.12 0.73 0.41 0.94 0.96 -0.64 -0.38 0.35 -0.13 -0.06 0.29 -0.05 -0.36 0.56 0.45
1486 || orf19.3841 || || || Putative protein serine/threonine kinase; predicted role in vesicle formation in autophagy and the cytoplasm-to-vacuole targeting (Cvt) pathway; Spider biofilm induced || 1 0.10 -0.10 0.83 0.73 1.64 1.29 -0.38 -0.31 -0.05 -0.53 -0.49 -0.05 0.10 -0.20 0.74 0.17
1487 || orf19.6544 || LPI9 || || Protein phosphatase type 1 regulator; role in chromosome segregation, regulation of phosphoprotein phosphatase activity; rat catheter and Spider biofilm induced || 1 0.08 0.15 0.43 0.12 0.68 0.48 0.10 -0.17 -0.02 -0.60 -0.26 0.20 0.16 -0.04 0.82 0.36
1488 || orf19.5974 || ATG9 || || Protein similar to S. cerevisiae Atg9; required for early step in autophagy; required for cytoplasm to vacuole trafficking of Lap41; Spider biofilm induced || 1 0.00 0.22 0.31 -0.14 0.97 0.55 0.24 -0.66 -0.14 -0.66 -0.40 0.19 -0.08 -0.25 0.51 0.65
1489 || orf19.3030 || || || Ortholog(s) have phosphatidylinositol binding activity || 1 0.24 0.08 0.03 0.01 0.66 0.56 0.08 -0.44 -0.34 -0.91 0.03 0.21 -0.06 -0.45 0.59 0.64
1490 || orf19.3169 || || || Ortholog(s) have role in RNA polymerase II complex localization to nucleus, RNA polymerase III complex localization to nucleus, establishment of mitotic sister chromatid cohesion and cytosol, nucleus localization || 1 0.11 0.00 0.28 0.13 0.87 1.35 -0.44 -0.41 -0.61 -0.49 0.47 0.19 -0.38 -0.00 0.60 0.68
1491 || orf19.1796 || || || Putative glyoxylate reductase; acts on glyoxylate and hydroxypyruvate substrates; Spider biofilm repressed || 1 0.11 -0.05 -0.08 -0.16 1.32 1.47 -1.11 -0.57 -0.83 -0.77 0.49 -0.23 -0.71 -0.33 0.30 0.65
1492 || orf19.5767 || || || Ortholog(s) have RNA binding activity and role in mRNA splicing, via spliceosome || 1 0.37 -0.13 0.09 -0.31 0.99 1.33 -0.55 -0.13 -0.41 -0.17 0.16 -0.09 -0.45 -0.08 0.21 0.29
1493 || orf19.1338 || || || Protein of unknown function; possible COPI-coated vesicle, Golgi apparatus, ribosome localization; rat catheter biofilm repressed || 1 0.35 0.20 0.17 -0.12 0.47 0.41 -0.14 0.06 -0.21 -0.34 -0.10 -0.01 -0.18 -0.28 0.05 0.33
1494 || orf19.1318 || || || Ortholog of C. dubliniensis CD36 : Cd36_43350, C. parapsilosis CDC317 : CPAR2_403560, Debaryomyces hansenii CBS767 : DEHA2A08250g and Pichia stipitis Pignal : PICST_29838 || 1 0.37 0.24 0.07 0.16 0.08 0.38 -0.07 -0.13 -0.37 -0.11 -0.26 0.05 -0.03 -0.03 0.40 -0.13
1495 || orf19.3336 || || || Ortholog of Candida albicans WO-1 : CAWG_01228 || 1 0.49 0.74 0.14 0.64 0.66 2.76 1.03 -0.54 -0.65 -2.67 0.27 0.66 -0.63 1.33 -0.50
1496 || orf19.215 || || || Component of a complex containing the Tor2p kinase; possible a role in regulation of cell growth; Spider biofilm induced || 1 -0.13 0.00 0.32 0.84 0.67 1.33 -0.04 -1.23 -1.48 -1.05 -0.73 0.25 -0.20 -0.28 0.85 -0.07
1497 || orf19.215 || || || Component of a complex containing the Tor2p kinase; possible a role in regulation of cell growth; Spider biofilm induced || 1 0.12 0.21 0.33 1.08 0.69 1.19 0.13 -0.99 -1.07 -0.72 -0.61 0.18 0.22 -0.33 0.88 -0.16
1498 || orf19.215 || || || Component of a complex containing the Tor2p kinase; possible a role in regulation of cell growth; Spider biofilm induced || 1 0.26 0.58 0.40 0.63 1.00 1.20 0.28 -0.94 -1.08 -0.74 -0.44 -0.00 0.06 0.28 0.95 -0.09
1499 || orf19.3331 || ABC1 || || Putative ubiquinol-cytochrome-c reductase; induced upon adherence to polystyrene; flow model biofilm induced; Spider biofilm induced || 1 0.21 0.22 0.68 0.60 0.59 1.25 -0.06 -0.97 -0.71 -0.51 -1.16 0.21 0.13 0.60 0.66 -0.27
1500 || orf19.3331 || ABC1 || || Putative ubiquinol-cytochrome-c reductase; induced upon adherence to polystyrene; flow model biofilm induced; Spider biofilm induced || 1 -0.12 -0.17 0.48 0.47 0.33 0.98 -0.02 -1.17 -0.83 -0.51 -1.51 -0.19 0.03 0.60 0.50 -0.24
1501 || orf19.2733 || || || Putative subunit of phosphatidylinositol 3-kinase complexes I and II; transcription is activated in the presence of elevated CO2 || 1 0.05 0.63 0.32 -0.37 1.69 0.65 0.83 -0.31 -0.48 0.13 0.03 0.49 -0.21 0.33 1.14 -0.65
1502 || orf19.2503 || || || Ortholog of S. cerevisiae : YGL138C, C. glabrata CBS138 : CAGL0H08910g, C. dubliniensis CD36 : Cd36_80910, C. parapsilosis CDC317 : CPAR2_102230 and Candida tenuis NRRL Y-1498 : CANTEDRAFT_109984 || 1 -0.29 0.35 0.44 -0.13 2.26 1.09 0.34 0.49 -1.59 -0.13 -0.12 0.91 0.86 -0.00 0.30 0.15
1503 || orf19.2423 || ZCF11 || || Zn(II)2Cys6 transcription factor; required for wild-type filamentous growth; mRNA binds She3 || 1 -0.05 -0.03 0.12 -0.01 0.90 0.32 0.05 0.19 -0.14 -0.55 0.09 0.40 0.32 0.05 0.48 0.34
1504 || orf19.4412 || || || Ortholog(s) have DNA-directed DNA polymerase activity, deoxycytidyl transferase activity and role in error-free translesion synthesis, error-prone translesion synthesis || 1 0.01 0.10 0.34 0.42 1.41 0.08 0.28 0.41 0.11 -0.36 0.03 0.54 0.03 -0.01 0.12 0.19
1505 || orf19.605 || || || Ortholog of Candida albicans WO-1 : CAWG_02087 || 1 0.05 0.33 0.12 0.65 1.16 0.62 -0.33 0.85 -0.39 -0.30 0.10 0.79 -0.12 0.19 0.74 0.06
1506 || orf19.3674 || GAL102 || || UDP-glucose 4,6-dehydratase; role in mannosylation of cell wall proteins; mutation confers hypersensitivity to toxic ergosterol analog; overlaps orf19.3673; Spider biofilm induced || 1 -0.14 -0.12 0.66 0.35 1.11 1.47 -0.33 -0.79 -2.00 -0.26 -0.03 -0.78 0.63 1.10 2.29 -0.86
1507 || orf19.7150 || NRG1 || || Transcription factor/repressor; regulates chlamydospore formation/hyphal gene induction/virulence and rescue/stress response genes; effects both Tup1 dependent and independent regulation; flow model biofilm induced; Spider biofilm repressed || 1 -0.19 -0.36 0.00 -0.67 -0.17 0.13 0.33 -0.96 -0.95 -0.93 -0.51 0.16 0.26 -0.40 0.86 -0.31
1508 || orf19.7150 || NRG1 || || Transcription factor/repressor; regulates chlamydospore formation/hyphal gene induction/virulence and rescue/stress response genes; effects both Tup1 dependent and independent regulation; flow model biofilm induced; Spider biofilm repressed || 1 0.13 0.02 0.08 -0.26 0.21 0.36 0.69 -0.80 -0.60 -0.77 -0.26 0.34 0.68 -0.24 1.20 0.07
1509 || orf19.7150 || NRG1 || || Transcription factor/repressor; regulates chlamydospore formation/hyphal gene induction/virulence and rescue/stress response genes; effects both Tup1 dependent and independent regulation; flow model biofilm induced; Spider biofilm repressed || 1 0.23 0.10 0.20 -0.27 0.38 0.57 0.77 -0.56 -0.68 -0.74 0.10 0.40 0.89 -0.12 1.25 0.13
1510 || orf19.7150 || NRG1 || || Transcription factor/repressor; regulates chlamydospore formation/hyphal gene induction/virulence and rescue/stress response genes; effects both Tup1 dependent and independent regulation; flow model biofilm induced; Spider biofilm repressed || 1 0.04 0.16 0.14 -0.15 0.31 0.69 0.77 -0.70 -0.72 -0.83 -0.18 0.48 0.87 -0.07 1.45 0.09
1511 || orf19.7150 || NRG1 || || Transcription factor/repressor; regulates chlamydospore formation/hyphal gene induction/virulence and rescue/stress response genes; effects both Tup1 dependent and independent regulation; flow model biofilm induced; Spider biofilm repressed || 1 0.24 0.19 0.22 -0.26 0.33 0.74 0.74 -0.65 -0.58 -0.77 -0.05 0.56 0.78 0.12 1.51 0.17
1512 || orf19.4077 || MIT1 || || Mannosylinositol phosphorylceramide (MIPC) synthase catalytic subunit; sphingolipid biosynthesis; fluconazole, caspofungin induced; macrophage-repressed; Spider biofilm induced || 1 0.00 -0.02 -0.27 -0.30 0.76 0.36 0.03 -0.83 -0.29 -0.40 -0.74 -0.25 -0.01 0.28 0.69 0.50
1513 || orf19.4077 || MIT1 || || Mannosylinositol phosphorylceramide (MIPC) synthase catalytic subunit; sphingolipid biosynthesis; fluconazole, caspofungin induced; macrophage-repressed; Spider biofilm induced || 1 -0.10 -0.22 -0.50 -0.46 0.98 0.42 0.09 -0.53 -0.28 -0.07 -0.72 -0.06 -0.09 0.38 1.05
1514 || orf19.7646 || || || Ortholog(s) have role in box C/D snoRNP assembly, protein folding, rRNA processing, regulation of cell size and R2TP complex, cytoplasm, nucleus, small nucleolar ribonucleoprotein complex localization || 1 0.45 0.28 -0.19 -0.08 0.54 0.52 -0.32 -0.90 0.19 0.00 -0.54 0.63 0.66 0.16 1.18 0.10
1515 || orf19.4166 || ZCF21 || || Predicted Zn(II)2Cys6 transcription factor; mutants display increased colonization of mouse kidneys; Spider biofilm induced || 1 0.01 0.03 -0.14 0.37 0.68 0.49 -0.03 -0.46 0.01 -0.16 -0.43 -0.21 0.59 0.19 1.11 -0.06
1516 || orf19.1595 || || || Ortholog(s) have Dsc E3 ubiquitin ligase complex, endoplasmic reticulum localization || 1 -0.17 -0.13 -0.25 0.00 0.30 0.07 -0.02 -0.34 0.00 -0.28 -0.18 0.02 0.31 0.08 0.68 0.26
1517 || orf19.4722 || RTG1 || || Ortholog(s) have sequence-specific DNA binding RNA polymerase II transcription factor activity || 1 -0.09 -0.01 -0.04 -0.16 0.17 0.15 -0.26 -0.07 0.06 -0.25 -0.06 -0.01 0.35 0.10 0.41 -0.04
1518 || orf19.7038 || || || Ortholog(s) have phosphatidylinositol-3-phosphate binding activity, role in protein targeting to vacuole and cytoplasm, nucleus localization || 1 0.26 0.28 0.09 0.01 0.52 0.10 -0.22 -0.26 -0.03 -0.21 -0.01 0.28 0.24 0.25 0.49 0.24
1519 || orf19.2440 || || || S. cerevisiae ortholog Rtt101 is a cullin subunit of E3 ubiquitin ligase complex with a role in anaphase progression; induced by alpha pheromone in SpiderM medium || 1 0.22 0.31 0.06 -0.37 0.43 0.03 -0.07 -0.19 -0.08 -0.04 -0.14 0.36 -0.03 0.23 0.34 0.17
1520 || orf19.449 || || || Putative phosphatidyl synthase; stationary phase enriched protein; transcript repressed by yeast-hypha switch; Hap43-repressed; rat catheter, Spider and flow model biofilm induced || 1 0.28 0.22 0.38 -0.07 0.46 0.72 -0.81 -1.65 -0.22 -1.26 0.17 0.19 -0.91 -0.10 2.24 0.84
1521 || orf19.449 || || || Putative phosphatidyl synthase; stationary phase enriched protein; transcript repressed by yeast-hypha switch; Hap43-repressed; rat catheter, Spider and flow model biofilm induced || 1 0.59 0.75 0.82 0.51 0.50 0.93 -0.85 -1.31 -0.22 -1.13 0.28 -0.03 -0.80 0.02 2.32 0.77
1522 || orf19.671 || PSP1 || || Protein repressed during the mating process || 1 0.01 0.01 0.17 0.31 0.07 0.08 -0.27 -0.36 -0.19 -0.19 -0.32 0.25 0.02 0.27 0.52 0.36
1523 || orf19.942 || KRE62 || || Putative subunit of glucan synthase; macrophage-induced gene; Bcr1-regulated in a/a RPMI biofilms || 1 0.50 0.44 0.55 -0.12 0.12 0.91 0.32 -0.59 -0.20 -0.51 -0.73 0.53 0.41 0.07 0.12 -0.06
1524 || orf19.2308 || || || Putative 6-phosphofructo-2-kinase; catalyzes synthesis of fructose-2,6-bisphosphate; Hap43-repressed; flow model, rat catheter and Spider biofilm induced || 1 0.93 1.02 0.41 0.11 0.39 1.29 1.02 -0.08 -0.20 -0.56 0.06 0.09 0.94 0.64 -0.23 0.25
1525 || orf19.2308 || || || Putative 6-phosphofructo-2-kinase; catalyzes synthesis of fructose-2,6-bisphosphate; Hap43-repressed; flow model, rat catheter and Spider biofilm induced || 1 0.83 0.97 0.23 0.06 0.43 1.22 0.72 0.03 -0.04 -0.53 -0.06 -0.18 0.88 0.74 -0.15 0.17
1526 || orf19.6091 || RIM8 || || Beta-arrestin-like protein; involved in pH response; required for pathogenesis, activation of Rim101 and alkaline pH-induced hyphal growth; colony morphology-related gene regulation by Ssn6p negative feedback regulation target || 1 0.41 0.44 0.00 -0.40 0.55 0.80 0.62 0.09 -0.12 -0.88 0.08 -0.04 0.64 0.44 -0.09 0.33
1527 || orf19.1162.1 || || || Ortholog(s) have Golgi apparatus localization || 1 0.77 0.74 0.05 -0.37 0.60 0.44 0.16 0.37 0.30 -0.58 0.15 0.23 0.37 -0.28 0.18 -0.10
1528 || orf19.3689 || || || Putative protein similar to 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase; expression downregulated in an ssr1 null mutant || 1 0.38 0.13 0.03 0.20 0.28 0.09 -0.51 -0.16 -0.28 -0.25 -0.31 0.07 -0.22 0.03 -0.09 0.26
1529 || orf19.6030 || || || Protein of unknown function; transcript detected on high-resolution tiling arrays || 1 0.38 0.37 0.18 0.03 0.19 0.24 0.19 -0.04 -0.19 -0.22 -0.14 0.17 -0.38 -0.14 -0.06 0.44
1530 || orf19.3905 || MRV5 || || Planktonic growth-induced gene || 1 0.05 0.42 0.39 0.45 0.35 0.73 -0.17 -0.30 -0.20 -0.69 -0.03 0.44 -0.75 -0.54 -0.02 0.20
1531 || orf19.4248 || || || Ortholog of S. cerevisiae YLR118C (alias Apt1); acyl-protein thioesterase responsible for depalmitoylation of Gpa1 in S. cerevisiae; regulated by Gcn4; repressed in response to amino acid starvation (3AT); rat catheter biofilm repressed || 1 0.25 0.22 0.10 0.08 0.36 0.92 -0.22 -0.20 -0.11 -0.36 -0.00 0.03 -0.87 -0.35 -0.29 0.13
1532 || orf19.704 || SOL3 || || Putative 6-phosphogluconolactonase; present in exponential and stationary growth phase yeast cultures; macrophage-downregulated protein; Spider biofilm repressed || 1 0.16 0.11 0.02 0.13 0.06 0.32 -0.25 0.03 -0.33 -0.15 0.14 0.01 -0.59 -0.09 -0.04 0.03
1533 || orf19.4220 || || || Predicted pyridoxal 5'-phosphate synthase; regulated by Gcn4; repressed by amino acid starvation (3-AT treatment); rat catheter biofilm repressed || 1 0.35 0.15 0.09 0.16 0.35 0.47 -0.22 0.20 -0.21 -0.18 0.26 0.12 -0.62 0.31 0.02 0.17
1534 || orf19.2721 || || || Ortholog(s) have role in ascospore formation, regulation of mitotic cell cycle, regulation of translation and cytosol, nucleus localization || 1 0.37 0.52 0.20 0.29 0.47 0.71 -0.04 0.19 -0.40 0.22 0.51 0.28 -0.47 0.16 0.12 0.11
1535 || orf19.704 || SOL3 || || Putative 6-phosphogluconolactonase; present in exponential and stationary growth phase yeast cultures; macrophage-downregulated protein; Spider biofilm repressed || 1 0.24 0.36 0.24 0.27 0.31 0.51 -0.14 0.10 -0.18 -0.10 0.25 0.11 -0.34 -0.13 -0.01 0.10
1536 || orf19.7149 || || || Putative GTPase inhibitor; predicted role in endocytosis, protein targeting to vacuole; rat catheter biofilm repressed || 1 0.32 0.28 -0.02 0.03 0.67 0.54 -0.22 0.03 -0.29 -0.24 0.56 0.01 -0.07 -0.06 -0.35 0.89
1537 || orf19.332 || || || Member of a complex that contains Prp19; stabilizes U6 snRNA in catalytic forms of the spliceosome containing U2, U5, and U6 snRNAs; Spider biofilm induced || 1 0.53 0.55 0.10 -0.05 0.63 1.00 -0.00 -0.21 0.00 -0.06 0.20 0.10 -0.35 0.18 -0.19 0.69
1538 || orf19.6881 || YTH1 || || Putative mRNA cleavage and polyadenylation specificity factor; transcription is regulated upon yeast-hyphal switch; decreased expression in hyphae compared to yeast-form cells; fluconazole or flucytosine induced || 1 0.43 0.55 0.17 -0.43 0.93 1.29 0.04 -0.30 -0.19 -0.70 0.28 -0.56 -0.76 0.47 -0.24 0.52
1539 || orf19.6881 || YTH1 || || Putative mRNA cleavage and polyadenylation specificity factor; transcription is regulated upon yeast-hyphal switch; decreased expression in hyphae compared to yeast-form cells; fluconazole or flucytosine induced || 1 0.75 0.77 -0.21 -0.42 0.98 0.89 0.26 -0.15 -0.40 -0.72 0.18 -0.90 -0.54 0.15 -0.23 0.25
1540 || orf19.7611 || TRX1 || || Thioredoxin; involved in response to reactive oxygen species; biofilm, benomyl, flucytosine, peroxide, Hap43 induced; amphotericin B, caspofungin repressed; induced by human neutrophils; macrophage-repressed gene || 1 0.33 0.27 -0.02 0.28 -0.26 -0.32 -0.14 -0.53 -0.04 -0.01 -0.47 0.37 -0.36 0.03
1541 || orf19.590 || || || Putative thiamine biosynthesis enzyme; decreased expression in an ssr1 null mutant; protein present in exponential and stationary growth phase yeast cultures || 1 0.51 0.24 -0.27 -0.29 0.19 0.46 -0.34 -0.53 -0.55 -0.41 -0.40 -0.23 -0.63 -0.00 -0.23 0.26
1542 || orf19.590 || || || Putative thiamine biosynthesis enzyme; decreased expression in an ssr1 null mutant; protein present in exponential and stationary growth phase yeast cultures || 1 0.59 0.45 -0.21 -0.14 0.39 0.52 -0.05 -0.34 -0.44 -0.48 -0.36 -0.16 -0.68 0.11 -0.05 0.39
1543 || orf19.5815 || SCT2 || || Putative glycerol-3-phosphate acyltransferase; fungal-specific (no human or murine homolog) || 1 0.16 0.03 -0.43 -0.46 0.41 0.37 -0.17 -0.37 0.03 -0.31 -0.25 0.34 -0.72 0.19 -0.00 0.51
1544 || orf19.6203 || PUT3 || || Zn(II)2Cys6 transcription factor; has similarity to S. cerevisiae Put3, a transcription factor involved in the regulation of proline utilization genes || 1 -0.00 -0.10 -0.03 -0.05 0.28 0.26 -0.17 -0.53 0.26 -0.21 -0.49 0.51 -0.43 0.02 0.15 -0.22
1545 || orf19.2006 || || || Ortholog(s) have fungal-type vacuole membrane localization || 1 0.05 -0.14 0.14 0.05 0.43 1.00 -0.26 -0.53 -0.02 -0.11 -0.10 0.60 -0.51 0.40 0.17 -0.03
1546 || orf19.7482 || || || Ortholog of C. parapsilosis CDC317 : CPAR2_803740, C. dubliniensis CD36 : Cd36_25640, Lodderomyces elongisporus NRLL YB-4239 : LELG_00467 and Candida orthopsilosis Co 90-125 : CORT_0A03760 || 1 -0.18 -0.16 -0.28 0.75 0.47 1.30 -0.29 -0.22 0.10 0.04 -0.28 0.99 -0.56 0.29 0.07 -0.63
1547 || orf19.1421 || || || Ortholog(s) have ureidoglycolate hydrolase activity and cytosol, nucleus localization || 1 -0.23 -0.33 -0.33 0.34 0.87 1.24 0.27 0.04 -0.36 -0.10 -0.35 0.30 -0.69 -0.73 0.63 0.51
1548 || orf19.6999 || || || Predicted oxidoreductase; rat catheter biofilm repressed || 1 0.11 -0.05 -0.30 0.19 1.66 -0.65 -0.44 0.02 0.29 -0.67 0.74 -1.23 -1.42 0.61 0.50
1549 || orf19.4682 || HGT17 || || Putative MFS family glucose transporter; 20 members in C. albicans; 12 probable membrane-spanning segments; induced at low (0.2%, compared to 2%) glucose in rich media; Spider biofilm induced || 1 -0.14 -0.18 -0.27 -0.12 0.59 0.78 -0.38 -0.59 0.38 0.09 -0.96 -0.22 -0.63 -1.02 0.20 0.13
1550 || orf19.4691 || MRV1 || || Ortholog of Candida albicans WO-1 : CAWG_03682 || 1 -0.65 -0.55 0.24 0.14 0.68 0.97 -0.27 -0.29 0.39 0.28 -1.10 0.32 -1.10 -0.48 0.06 0.34
1551 || orf19.3009 || || || Ortholog of S. cerevisiae : YDR179W-A, C. glabrata CBS138 : CAGL0F05819g, C. dubliniensis CD36 : Cd36_02970, C. parapsilosis CDC317 : CPAR2_108540 and Candida tenuis NRRL Y-1498 : CANTEDRAFT_132957 || 1 -0.16 -0.25 0.10 -0.18 0.25 0.47 0.03 -0.17 0.37 -0.03 -0.43 0.28 -0.42 -0.07 0.16 -0.12
1552 || orf19.4919 || || || Has domain(s) with predicted DNA binding, nucleic acid binding activity || 1 0.10 -0.07 0.10 0.09 0.02 0.70 -0.03 -0.18 0.33 0.30 -0.43 0.17 -0.57 0.05 0.36 0.17
1553 || orf19.2266 || || || Ortholog(s) have ATPase activity, DNA binding, nucleosome binding activity, role in chromatin remodeling and Isw1 complex localization || 1 -0.10 -0.38 0.15 -0.09 0.47 0.75 -0.39 -0.18 0.12 0.41 -0.18 0.54 -0.48 0.07 0.14 0.46
1554 || orf19.5930 || || || Ortholog(s) have nucleocytoplasmic transporter activity, structural constituent of nuclear pore activity || 1 -0.43 -0.27 0.32 0.23 -0.11 0.87 -0.39 -0.85 0.52 0.08 -0.13 0.43 -0.32 0.20 -0.00 0.68
1555 || orf19.2177 || || || Sef1p-, Sfu1p-, and Hap43p-regulated gene; overlaps IFM3/orf19.2176 || 1 -0.41 -0.34 -0.21 1.18 1.55 -0.58 -1.37 2.84 -0.24 -0.65 0.47 -1.40 -0.27 -0.23 1.81
1556 || orf19.1563 || ECM3 || || Ortholog(s) have endoplasmic reticulum localization || 1 0.06 -0.10 -0.14 0.24 0.56 0.67 0.21 -0.02 0.65 -0.08 -0.28 0.48 0.02 -0.29 -0.28 0.47
1557 || orf19.7331 || FCY24 || || Putative transporter; more similar to S. cerevisiae Tpn1, which is a vitamin B6 transporter, than to purine-cytosine permeases; transcription is regulated by Nrg1; Spider biofilm induced || 1 -0.44 -0.47 0.12 -0.33 0.59 1.16 0.04 -0.19 0.89 -0.49 -0.34 0.35 -0.09 -0.06 -0.51 0.01
1558 || orf19.4451 || RIA1 || || Putative translation elongation factor; genes encoding ribosomal subunits, translation factors, and tRNA synthetases are downregulated upon phagocytosis by murine macrophage || 1 -0.16 0.05 0.11 -0.38 0.50 1.11 0.13 0.07 0.57 -0.30 -0.08 0.20 -0.08 -0.41 -0.20 0.04
1559 || orf19.5304 || || || Ortholog of C. dubliniensis CD36 : Cd36_43800 and Candida albicans WO-1 : CAWG_03395 || 1 0.37 0.60 -1.68 0.46 3.35 -0.40 0.68 2.23 -0.16 -0.25 -0.23 -0.29 -0.03 0.36
1560 || orf19.4861.1 || || || Protein of unknown function || 1 -0.07 -0.36 0.65 -0.02 0.05 1.50 -0.25 0.00 -0.04 0.00 0.00 0.15 -0.36 -0.16 0.12
1561 || orf19.3719 || || || Dubious open reading frame || 1 0.45 -0.02 1.11 -0.08 -0.48 2.22 0.19 -0.21 0.62 0.04 -0.02 -0.49 -0.07 -0.05 -0.76 -0.12
1562 || orf19.3503 || || || Ortholog of Candida albicans WO-1 : CAWG_05160 || 1 -0.14 -0.34 0.91 -0.31 2.95 0.51 0.67 0.02 0.58 -0.42 0.57 0.98 0.45
1563 || orf19.5264 || || || Dubious open reading frame || 1 -0.41 -0.58 -0.44 -0.17 5.59 0.09 0.89 0.47 -0.95 -0.26 -0.02 -0.72 -2.76 0.35 0.19
1564 || orf19.1456 || || || Ortholog of Candida albicans WO-1 : CAWG_03922 || 1 0.55 -0.12 0.69 0.90 0.08 1.61 -0.30 0.33 0.21 0.09 -0.33 0.11 -0.43 -0.76 0.71 0.03
1565 || orf19.1582 || || || Predicted membrane transporter; member of the drug:proton antiporter (12 spanner) (DHA1) family, major facilitator superfamily (MFS); mRNA binds She3 || 1 0.41 -0.53 0.33 -0.13 0.31 0.92 -0.71 0.31 0.33 -0.02 0.09 0.84 -0.30 -0.73 -0.00 1.38
1566 || orf19.7449 || || || Ortholog(s) have role in mitochondrial genome maintenance, plasmid maintenance and cytosol, mitochondrion localization || 1 0.87 0.05 -0.14 -0.34 0.59 0.82 0.19 -0.46 0.10 0.04 0.23 0.14 -0.05 0.34 0.64 0.76
1567 || orf19.1121 || || || Has domain(s) with predicted hydrolase activity || 1 -0.06 0.36 0.21 0.07 0.63 0.41 0.46 -0.19 0.17 -0.14 0.25 0.33 -0.15 0.30 -0.25 0.17
1568 || orf19.4741 || || || Protein of unknown function; C. albicans- and C. dubliniensis specific gene; rat catheter biofilm repressed || 1 0.34 1.29 0.43 0.44 1.10 0.20 -0.85 -0.43 -1.09 -0.06 0.08 -0.33 -0.40
1569 || orf19.1121 || || || Has domain(s) with predicted hydrolase activity || 1 0.13 0.29 -0.02 0.08 0.60 0.04 0.12 -0.11 -0.09 -0.50 0.25 0.15 -0.22 -0.35 -0.11 0.03
1570 || orf19.6465 || || || Ortholog of C. dubliniensis CD36 : Cd36_83910, Candida tropicalis MYA-3404 : CTRG_05087 and Candida albicans WO-1 : CAWG_00654 || 1 0.05 -0.05 0.40 -0.02 1.15 0.43 0.50 0.02 0.00 -0.36 0.57 -0.69 0.11 -0.75 0.44 -0.16
1571 || orf19.653 || || || Dubious open reading frame || 1 -0.08 0.11 0.49 1.00 0.61 1.28 -0.34 -0.06 1.12 -0.18 0.45 0.02
1572 || orf19.5223 || || || Ortholog of Candida albicans WO-1 : CAWG_00199 || 1 0.11 0.32 0.31 0.24 0.38 -0.03 0.76 0.05 -0.23 -0.29 0.35 -0.09 0.32 -0.23 0.09 -0.09
1573 || orf19.2429 || || || Protein of unknown function; induced by alpha pheromone in SpiderM medium || 1 0.36 0.39 1.00 1.16 0.21 0.12 0.56 -0.90 -0.35 -0.41 1.17 -0.47 -0.51 -1.07 -0.87 0.32
1574 || orf19.5502 || || || Ortholog of C. dubliniensis CD36 : Cd36_73420, Debaryomyces hansenii CBS767 : DEHA2A05456g, Pichia stipitis Pignal : PICST_30999 and Candida guilliermondii ATCC 6260 : PGUG_00155 || 1 -0.21 -0.22 0.60 1.30 1.26 0.39 -0.26 0.11 -0.50 0.29 -0.82 -0.58 -0.08 -0.67 -0.75
1575 || orf19.1557 || || || Ortholog(s) have S-adenosylmethionine-dependent methyltransferase activity, role in protein methylation and cytosol, nucleus localization || 1 0.31 0.24 0.70 0.64 1.16 0.20 0.04 0.21 0.31 0.15 -0.17 -0.56 -0.22 0.31 -0.74 -0.45
1576 || orf19.6957 || || || Protein of unknown function || 1 -0.37 0.96 0.84 0.48 1.40 -0.30 0.23 -0.10 -0.49 0.03 0.07 -0.18 0.03 -1.32 -0.12
1577 || orf19.3655 || || || Ortholog of C. dubliniensis CD36 : Cd36_60640, C. parapsilosis CDC317 : CPAR2_602930, Candida tenuis NRRL Y-1498 : CANTEDRAFT_115038 and Pichia stipitis Pignal : PICST_31932 || 1 -0.29 0.32 0.20 0.54 0.31 0.26 0.07 0.18 -0.01 0.09 -0.06 0.26 -0.26 0.20 -0.56 -0.56
1578 || orf19.5724 || || || Ortholog of C. parapsilosis CDC317 : CPAR2_500910, C. dubliniensis CD36 : Cd36_64110, Candida tenuis NRRL Y-1498 : CANTEDRAFT_115913 and Pichia stipitis Pignal : PICST_32870 || 1 -0.36 0.23 0.34 0.15 0.88 -0.29 0.18 0.02 0.27 0.49 0.11 0.00 -0.13 0.40 -0.18
1579 || orf19.7622 || SPT3 || || Functional homolog of S. cerevisiae Spt3p; required for virulence in mouse systemic infection; homozygous null mutant is hyperfilamentous || 1 -0.12 0.31 0.35 0.05 0.06 -0.27 0.05 0.36 0.12 0.29 0.12 -0.13 0.14 0.01 0.41 0.01
1580 || orf19.1580 || || || Protein of unknown function; Spider biofilm induced || 1 -0.01 0.05 0.22 0.41 0.09 -0.33 0.07 0.12 0.88 0.44 -0.39 -0.49 0.20 -0.12 0.74 -0.20
1581 || orf19.7379 || FAA2 || || Putative acyl CoA synthetase; expression regulated upon white-opaque switch; rat catheter biofilm induced; Spider biofilm induced || 1 0.11 -0.09 0.83 0.59 0.18 -0.40 0.06 -0.01 0.60 0.94 -0.27 -0.20 0.38 0.34 0.38 -0.42
1582 || orf19.1943 || || || Ortholog of C. parapsilosis CDC317 : CPAR2_302610, C. dubliniensis CD36 : Cd36_51070, Candida orthopsilosis Co 90-125 : CORT_0E04770 and Spathaspora passalidarum NRRL Y-27907 : SPAPADRAFT_50634 || 1 0.76 0.94 0.74 0.64 0.75 -1.05 0.26 -0.90 0.53 0.16 -0.80 0.19 0.16 -0.03
1583 || orf19.2479 || UGA4 || || Putative gamma-aminobutyric acid/polyamine permease; nitrogen catabolite repressed gene, induced in absence of preferred N sources; transcriptionally induced upon phagocytosis by macrophage; gene regulation by nitrogen source requires Gat1p || 1 0.42 0.21 0.58 0.55 0.81 -0.25 0.03 -0.19 0.18 0.80 -0.07 -1.25 0.11 -0.21 0.14 0.12
1584 || orf19.4070 || || || Ortholog of C. dubliniensis CD36 : Cd36_23270 || 1 0.06 0.29 0.41 -0.01 0.34 -0.23 -0.34 -0.23 1.34 0.91 -0.91 -0.97 0.37 -0.06 -0.93 -0.45
1585 || orf19.2797 || || || Has domain(s) with predicted ATP binding, DNA binding, helicase activity || 1 0.17 -0.04 0.30 0.02 -0.02 0.52 -0.16 -0.28 0.65 0.30 -0.61 -0.53 -0.02 -0.08 -0.14 -0.17
1586 || orf19.6302 || PGA39 || || Putative GPI-anchored protein || 1 0.47 0.27 0.59 0.84 0.29 0.51 -0.42 -0.73 0.62 0.53 -0.26 -0.51 0.22 -0.76 -0.51 0.11
1587 || orf19.3468 || ALG11 || || Alpha-1,2-mannosyltransferase; catalyzes sequential addition of 2 terminal alpha 1,2-mannose residues to the Man5GlcNAc2-PP-dolichol intermediate during asparagine-linked glycosylation in the ER; Spider biofilm induced || 1 0.32 0.61 1.05 0.77 0.31 -0.57 -0.58 -0.46 0.46 0.74 -0.11 -0.43 0.56 -0.48 -0.97 -0.10
1588 || orf19.4392 || DEM1 || || Putative mitochondrial exonuclease; alpha-factor induced || 1 0.58 -0.12 0.57 0.88 0.08 -0.10 -0.29 0.14 0.82 0.22 -0.50 -0.24 -0.26 -0.16 -0.93 -0.05
1589 || orf19.298 || || || Protein of unknown function; flow model biofilm induced || 1 0.65 -0.73 0.11 0.63 1.17 0.39 -0.59 1.00 0.44 0.23 -0.31 0.43 -0.59 -0.57 -0.29
1590 || orf19.3208 || DAL52 || || Putative allantoate permease; mutant is viable; similar but not orthologous to S. cerevisiae Dal5 || 1 0.17 0.03 0.54 0.22 -0.11 0.45 0.50 -0.39 0.29 0.41 0.13 -0.57 0.64 -0.34 -0.54 0.31
1591 || orf19.5259 || || || Ortholog of C. dubliniensis CD36 : Cd36_11290, C. parapsilosis CDC317 : CPAR2_805090, Pichia stipitis Pignal : PICST_28850 and Candida guilliermondii ATCC 6260 : PGUG_02709 || 1 -0.09 0.12 0.54 0.29 -0.06 0.05 0.71 -0.16 0.24 -0.14 -0.02 0.30 0.28 -0.28 -0.42 0.03
1592 || orf19.599 || || || Dubious open reading frame || 1 -0.14 0.74 1.51 0.85 -0.12 1.84 -0.53 -0.39 0.38 0.18 0.23 0.86 0.70 -0.16
1593 || orf19.2146 || HAT2 || || Putative Hat1-Hat2 histone acetyltransferase complex subunit; role in DNA damage repair and morphogenesis; mutations cause constitutive pseudohyphal growth, caspofungin sensitivity; rat catheter and Spider biofilm repressed || 1 0.28 -0.32 0.66 0.70 -0.26 -0.31 -0.02 0.35 0.35 0.12 0.44 -0.24 -0.24 -0.13 -0.24 -0.07
1594 || orf19.5768 || SNF4 || || Transcription factor; ortholog of S. cerevisiae Snf4; caspofungin repressed; transposon mutation affects filamentation || 1 0.24 0.14 0.74 0.38 -0.07 -0.19 0.29 0.98 0.02 -0.20 0.75 -0.08 0.17 0.19 0.00 0.00
1595 || orf19.1526 || SNF2 || || Protein involved in transcriptional regulation; ortholog of S. cerevisiae Snf2p, which is the catalytic subunit of the SWI/SNF chromatin remodeling complex; interacts with Swi1p; SWI/SNF complex is essential for hyphal growth and virulence || 1 0.41 0.32 0.06 0.08 0.18 -0.09 -0.16 0.18 -0.25 -0.01 0.61 0.29 0.64 0.10 0.16 -0.20
1596 || orf19.2827 || || || Ortholog(s) have structural constituent of cytoskeleton activity || 1 0.52 0.58 0.40 0.35 -0.25 -0.23 0.04 0.32 -0.23 -0.47 0.42 0.40 0.80 0.13 -0.03 -0.02
1597 || orf19.3461 || || || Protein of unknown function; oxidative stress-induced via Cap1; induced by alpha pheromone in SpiderM medium || 1 0.37 1.49 0.60 0.73 -0.04 -0.81 -0.11 0.46 -0.61 -0.75 0.70 -0.36 0.34 1.03 0.29 1.33
1598 || orf19.1588 || || || Putative mitochondrial protein of unknown function; regulated by Sef1p-, Sfu1p-, and Hap43p || 1 0.59 0.65 0.30 0.34 -0.05 -0.30 0.16 0.40 -0.24 -0.47 0.25 -0.23 0.65 0.55 -0.12 0.33
1599 || orf19.1588 || || || Putative mitochondrial protein of unknown function; regulated by Sef1p-, Sfu1p-, and Hap43p || 1 0.56 0.52 0.04 -0.12 -0.16 -0.49 0.01 0.25 -0.49 -0.71 0.12 -0.51 0.47 0.52 -0.07 0.10
1600 || orf19.642 || || || Ortholog of C. dubliniensis CD36 : Cd36_30470, C. parapsilosis CDC317 : CPAR2_203380, Candida tenuis NRRL Y-1498 : CANTEDRAFT_117493 and Debaryomyces hansenii CBS767 : DEHA2G19228g || 1 0.51 0.54 0.18 -0.22 0.13 -0.28 0.06 -0.03 0.03 -0.08 -0.10 0.02 0.41 0.17 0.04 0.10
1601 || orf19.7321 || || || Ortholog(s) have role in re-entry into mitotic cell cycle after pheromone arrest and endoplasmic reticulum localization || 1 0.49 0.50 0.25 0.25 0.13 -0.30 0.07 0.24 0.02 -0.33 -0.11 0.11 0.02 -0.01 0.38 0.12
1602 || orf19.6715 || || || Ortholog of Candida albicans WO-1 : CAWG_03078 || 1 0.34 1.64 0.40 0.09 0.20 -0.44 0.19 0.54 -0.27 -0.45 -0.25 0.01 0.08 -0.14 0.54 -0.04
1603 || orf19.4210 || || || Ortholog(s) have phospholipase A2 activity, role in cardiolipin acyl-chain remodeling and mitochondrion localization || 1 0.23 0.58 0.01 0.29 -0.49 -0.17 0.26 0.28 0.28 0.12 -0.26 -0.06 0.51 0.26 0.22 -0.36
1604 || orf19.6983 || || || Protein of unknown function; Hap43-repressed gene; repressed by nitric oxide; Spider biofilm induced || 1 1.07 0.62 0.96 1.36 -2.05 -0.97 1.05 -0.08 0.21 -0.50 -0.83 -1.05 2.36 -0.09 1.17 -0.72
1605 || orf19.6983 || || || Protein of unknown function; Hap43-repressed gene; repressed by nitric oxide; Spider biofilm induced || 1 0.58 0.66 1.13 1.33 -1.76 -0.19 1.09 -0.28 0.45 0.00 -0.70 -0.43 2.35 0.78 1.66 -0.02
1606 || orf19.2125 || || || Protein of unknown function; GlcNAc-induced protein; Spider biofilm induced; rat catheter biofilm repressed || 1 2.23 2.31 2.46 2.05 -1.38 -0.79 1.19 0.26 -0.23 -2.43 -0.48 -0.57 2.24 0.91 0.20 -0.31
1607 || orf19.2125 || || || Protein of unknown function; GlcNAc-induced protein; Spider biofilm induced; rat catheter biofilm repressed || 1 1.79 1.71 1.84 1.34 -1.82 -1.24 0.69 -0.25 -0.51 -2.32 -0.89 -1.09 1.79 0.80 -0.22 -0.55
1608 || orf19.6644 || || || Protein of unknown function; 2 predicted transmembrane domains; transcript detected on high-resolution tiling arrays; flow model biofilm induced; Spider biofilm repressed || 1 0.67 0.86 0.42 0.73 -0.49 -0.86 0.04 -0.13 -0.61 -0.62 0.16 -0.30 0.72 0.14 0.23 0.28
1609 || orf19.5897 || || || Ortholog(s) have Seh1-associated complex, cytosol, extrinsic to fungal-type vacuolar membrane localization || 1 0.52 -0.04 0.78 0.43 -0.02 -0.08 0.25 0.07 0.01 -0.57 -0.07 -0.20 1.18 -0.38 0.29 -0.10
1610 || orf19.4539 || || || Protein with a Rho GDP-dissociation inhibitor domain; Hap43-repressed gene; Spider biofilm induced || 1 0.19 0.14 0.33 0.50 -0.09 -0.59 0.20 0.64 0.19 0.14 -0.62 0.09 0.39 0.02 0.22 -0.01
1611 || orf19.6704 || || || Protein of unknown function; Hap43-repressed gene || 1 0.84 0.25 0.01 0.26 0.10 -0.73 0.42 0.61 0.66 -0.20 -0.49 -0.72 0.64 0.19 0.14 0.42
1612 || orf19.6971 || DIE2 || || Ortholog(s) have dolichyl-phosphate-glucose-glycolipid alpha-glucosyltransferase activity, role in protein N-linked glycosylation and endoplasmic reticulum membrane localization || 1 0.54 0.72 0.22 0.19 0.02 -0.66 0.40 0.41 0.31 0.14 -0.05 0.55 0.15 0.68 -0.29 0.63
1613 || orf19.1792 || || || Ortholog(s) have ubiquitin-protein ligase activity || 1 0.12 0.56 0.32 0.20 0.08 -0.48 0.01 -0.01 0.34 0.19 0.19 0.13 -0.08 0.76 -0.28 0.54
1614 || orf19.3939 || || || Ortholog(s) have role in protein folding in endoplasmic reticulum and ER membrane protein complex, cell division site, cytosol, mitotic spindle pole body, nucleus localization || 1 0.12 0.20 0.31 0.34 0.10 -0.16 -0.12 0.08 0.35 0.20 0.09 0.32 -0.01 0.10 -0.22 0.43
1615 || orf19.1630 || || || Ortholog(s) have cytoplasm localization || 1 0.25 0.16 0.25 0.22 0.04 -0.17 -0.11 0.18 0.13 0.08 0.13 0.20 -0.26 -0.01 -0.21 0.32
1616 || orf19.3199 || PIKA || || Putative phosphatidylinositol kinase; non-sex gene located within the MTLa mating-type-like locus || 1 0.37 0.33 0.56 0.24 -0.02 0.04 0.03 0.17 0.39 -0.16 0.14 -0.08 -0.09 -0.04 -0.38 0.64
1617 || orf19.6487 || || || Ortholog of C. parapsilosis CDC317 : CPAR2_808350, C. dubliniensis CD36 : Cd36_72060, Candida orthopsilosis Co 90-125 : CORT_0C00820 and Candida albicans WO-1 : CAWG_05575 || 1 1.33 1.79 0.84 0.77 -1.02 -0.26 0.14 0.69 1.57 0.27 -0.32 -0.44 0.28 -0.99 1.01
1618 || orf19.3281 || || || Ortholog(s) have histone demethylase activity (H3-K36 specific), methylated histone residue binding activity and role in histone demethylation || 1 0.29 1.11 0.55 0.74 -0.50 -0.13 0.11 0.22 0.71 -0.15 0.05 0.40 -0.12 -0.20 -0.06 0.29
1619 || orf19.3052 || YPT1 || || Functional homolog of S. cerevisiae Ypt1p, which is an essential small Ras-type GTPase involved in protein secretion at ER-to-Golgi; dominant-negative mutation causes SAP secretion defect and accumulation of intracellular secretory vesicles || 1 0.78 0.69 0.63 0.58 0.23 0.23 -0.34 0.17 -0.22 0.27 0.06 0.00 -0.35 -0.22 -0.08 0.29
1620 || orf19.4306 || || || Ortholog(s) have methylthioribulose 1-phosphate dehydratase activity, role in L-methionine salvage from methylthioadenosine and cytoplasm localization || 1 1.78 1.63 1.20 1.54 -0.16 0.05 -0.26 0.40 0.12 0.44 0.45 0.16 -1.06 0.19 -0.52 -0.44
1621 || orf19.1606 || || || Protein of unknown function; Plc1-regulated || 1 1.53 1.48 1.02 0.91 0.76 -0.76 -0.81 -0.23 -0.31 0.19 0.15 -0.25 0.05 -0.05 -0.58
1622 || orf19.1606 || || || Protein of unknown function; Plc1-regulated || 1 2.05 2.17 0.97 1.91 0.90 -0.87 0.01 -0.14 0.13 0.56 0.26 0.02 0.15 0.46 -0.53
1623 || orf19.2752 || ADR1 || || C2H2 transcription factor; ortholog of S. cerevisiae Adr1 but mutant phenotype suggests a different set of target genes; transposon mutation affects filamentous growth; Spider biofilm induced || 1 0.84 0.74 0.66 1.11 0.35 -0.11 -0.24 -0.10 -0.13 0.44 -0.28 -0.01 0.30 -0.11 0.38 -0.83
1624 || orf19.1757 || || || Putative C2H2 transcription factor; expression upregulated in clinical isolates from HIV+ patients with oral candidiasis; Spider biofilm induced || 1 1.06 0.91 0.11 0.51 0.05 0.02 -0.06 0.01 -0.30 0.46 0.01 -0.02 0.57 -0.17 0.34 -0.68
1625 || orf19.1793 || || || Ortholog(s) have phosphatidylinositol binding activity, role in cellular response to nitrogen starvation, piecemeal microautophagy of nucleus and Golgi apparatus, endosome, extrinsic to membrane, fungal-type vacuole localization || 1 0.30 0.28 0.23 0.75 0.10 -0.19 0.26 0.17 0.02 0.55 -0.24 -0.38 0.09 0.21 -0.05 -0.22
1626 || orf19.2317 || || || Protein of unknown function; induced by alpha pheromone in SpiderM medium || 1 0.32 0.55 1.57 1.49 0.30 -0.01 0.51 0.28 0.99 1.64 -0.36 -0.58 0.04 -0.54 -0.31 -0.70
1627 || orf19.4981 || || || Ortholog(s) have endoplasmic reticulum localization || 1 0.52 0.12 0.69 0.95 -0.38 -0.35 0.62 0.43 0.50 0.75 -0.34 0.02 -0.01 -0.23 -0.20 -0.32
1628 || orf19.3013 || CDC12 || || Septin; essential for viability; forms ring at sites of cell division and also forms filaments in mature chlamydospore; filamentous growth induced; regulated by Nrg1, Tup1, tyrosol and cell density; rat catheter biofilm repressed || 1 0.07 0.15 0.67 0.89 -0.20 -0.80 -0.04 0.34 0.26 0.65 0.07 -0.01 0.16 0.33 -0.34 -0.08
1629 || orf19.3673 || || || Ortholog(s) have Rab guanyl-nucleotide exchange factor activity, role in ER to Golgi vesicle-mediated transport, chromosome organization and TRAPP complex, cytosol, nucleus localization || 1 0.20 0.08 1.17 0.73 -0.02 -0.32 -0.02 0.37 0.19 0.50 0.24 -0.07 0.21 0.20 -0.01 -0.04
1630 || orf19.433 || || || Ortholog(s) have Rab guanyl-nucleotide exchange factor activity, role in intra-Golgi vesicle-mediated transport, protein complex assembly and TRAPP complex, trans-Golgi network localization || 1 0.22 0.27 1.13 1.03 0.01 -0.25 0.09 0.23 0.52 0.39 0.02 0.15 0.16 0.28 -0.32 -0.22
1631 || orf19.576 || CTF8 || || Putative kinetochore protein with a predicted role in sister chromatid cohesion; repressed during the mating process; flow model biofilm induced || 1 -0.05 -0.05 0.94 1.14 0.08 -0.23 -0.12 0.48 0.24 0.40 0.19 -0.29 -0.14 0.44 -0.41 -0.29
1632 || orf19.4367 || SMC1 || || Protein similar to chromosomal ATPases; RNA abundance regulated by tyrosol and cell density; cell-cycle regulated periodic mRNA expression || 1 0.55 0.67 1.57 1.26 0.34 0.13 -0.32 0.08 -0.00 0.55 0.15 -0.40 0.29 0.13 -0.48 -0.14
1633 || orf19.4643 || || || Ortholog of C. dubliniensis CD36 : Cd36_41430, Candida tropicalis MYA-3404 : CTRG_00187 and Candida albicans WO-1 : CAWG_03642 || 1 0.34 0.61 1.04 0.89 0.38 -0.10 -0.16 0.31 -0.02 0.67 -0.00 -0.04 0.36 0.40 -0.23 0.15
1634 || orf19.5575 || || || Putative peripheral peroxisomal membrane peroxin; required for regulating peroxisome size and maintenance; Spider biofilm induced || 1 0.42 0.55 0.66 0.43 0.08 0.00 -0.01 0.08 0.39 0.62 -0.25 0.23 0.31 0.17 0.09 -0.42
1635 || orf19.5789 || ADE8 || || Putative phosphoribosylglycinamide formyl-transferase, enzyme of amino acid biosynthesis pathway; upregulated in biofilm; S. cerevisiae ortholog is Gcn4p regulated; protein enriched in stationary phase yeast-form cultures || 1 0.64 0.67 0.56 0.58 -0.09 -0.01 -0.22 0.54 0.21 0.71 -0.12 -0.17 0.34 0.13 -0.48 -0.56
1636 || orf19.4120 || LAS1 || || Putative bud formation and morphogenesis protein; mutation confers hypersensitivity to 5-fluorocytosine (5-FC), 5-fluorouracil (5-FU); macrophage-induced; Spider biofilm induced || 1 0.35 0.50 0.52 0.41 0.10 0.05 -0.10 0.10 0.28 0.65 -0.46 -0.30 0.68 0.14 -0.57 -0.82
1637 || orf19.4568 || ZCF25 || || Putative Zn(II)2Cys6 transcription factor || 1 0.44 0.52 0.33 0.19 -0.42 -0.19 0.23 0.55 0.26 0.39 -1.00 -0.70 -0.11 -0.16 -0.50 -0.59
1638 || orf19.6794 || FESUR1 || || Putative ubiquinone reductase; transcriptionally induced by interaction with macrophage; alkaline downregulated; repressed by nitric oxide; clade-associated gene expression; Hap43p-repressed gene || 1 0.91 0.69 0.46 0.59 -0.79 -0.33 0.38 0.76 0.34 0.52 -0.60 -0.18 -0.47 -0.45 -0.07 -0.68
1639 || orf19.4153 || || || Ortholog(s) have NEDD8 activating enzyme activity, role in protein neddylation and cytosol, nucleus localization || 1 0.87 0.70 0.17 0.58 -0.28 -0.36 0.46 0.32 -0.06 0.46 -0.63 -0.36 0.04 -0.31 -0.33 -0.20
1640 || orf19.2813 || || || Ortholog of Candida albicans WO-1 : CAWG_02711 || 1 1.38 1.29 0.78 1.71 -1.06 -0.13 1.17 0.21 0.93 0.21 -1.33 -0.98 -0.63 -0.03 -1.38 -0.46
1641 || orf19.5750 || SHM2 || || Cytoplasmic serine hydroxymethyltransferase; complements glycine auxotrophy of S. cerevisiae shm1 shm2 gly1-1 mutant; antigenic; farnesol-upregulated in biofilm; stationary-phase enriched protein; rat catheter and Spider biofilm repressed || 1 0.64 0.51 0.03 0.55 -0.38 -0.13 0.25 0.37 0.51 0.08 -0.38 -0.14 -0.33 0.30 -0.14 -0.34
1642 || orf19.6788 || || || Protein with a predicted role in cotranslational protein targeting to membrane; induced during chlamydospore formation in both C. albicans and C. dubliniensis || 1 0.63 0.62 0.63 0.49 -0.23 -0.06 0.22 0.21 -0.02 -0.25 -0.32 -0.19 0.14 -0.05 0.40 -0.24
1643 || orf19.3554 || AAT1 || || Aspartate aminotransferase; soluble protein in hyphae; macrophage-induced protein; alkaline upregulated; amphotericin B repressed; gene used for strain identification by multilocus sequence typing; farnesol-, Hap43p-induced; GlcNAc-induced || 1 0.74 0.81 1.12 0.71 -0.15 -0.62 -0.04 -0.00 -0.43 -0.44 -0.73 -0.49 -0.15 0.09 -1.29 -0.16
1644 || orf19.6127 || LPD1 || || Putative dihydrolipoamide dehydrogenase; soluble in hyphae; antigenic in human oral infection and murine systemic infection; macrophage-induced protein; protein present in exponential and stationary phase yeast cultures; Hap43p-repressed || 1 0.67 0.68 0.53 0.63 -0.21 0.12 0.00 -0.19 -0.08 -0.20 -0.53 -0.49 0.07 -0.03 -0.44 -0.29
1645 || orf19.789 || PYC2 || || Putative pyruvate carboxylase; binds biotin cofactor; repressed by Ssk1 response regulator, by benomyl treatment, or in an azole-resistant strain overexpressing MDR1; stationary phase enriched protein; flow model biofilm repressed || 1 1.70 1.78 1.37 1.57 -0.62 -0.72 -0.50 -0.85 -0.35 0.34 -1.02 -0.78 -0.06 -0.15 -1.15 -0.02
1646 || orf19.577 || || || Predicted protein tyrosine phosphatase; rat catheter biofilm induced || 1 0.77 0.76 0.71 0.67 -0.47 -0.36 -0.14 0.01 -0.17 -0.05 -0.61 -0.34 -0.44 0.14 -0.20 0.05
1647 || orf19.3705 || PTC6 || || Mitochondrial protein phosphatase of the Type 2C-related family (serine/threonine-specific), functional homolog of S. cerevisiae Ptc6p; mutant shows virulence defect || 1 1.06 0.83 0.76 0.79 -0.65 -0.33 -0.17 -0.03 0.06 0.03 -0.71 -0.45 -0.56 0.59 -0.49 -0.06
1648 || orf19.3705 || PTC6 || || Mitochondrial protein phosphatase of the Type 2C-related family (serine/threonine-specific), functional homolog of S. cerevisiae Ptc6p; mutant shows virulence defect || 1 1.00 0.96 0.46 0.66 -0.49 -0.23 -0.02 -0.04 0.11 -0.08 -0.66 -0.47 -0.41 0.45 -0.51 -0.03
1649 || orf19.7043 || || || Ortholog(s) have endoplasmic reticulum localization || 1 1.63 1.44 0.88 1.31 -0.86 -0.39 -0.23 0.23 -0.04 -0.08 -0.42 -0.22 0.13 0.25 -0.92 0.08
1650 || orf19.577 || || || Predicted protein tyrosine phosphatase; rat catheter biofilm induced || 1 1.21 1.20 0.76 0.66 -0.01 -0.34 0.05 0.14 -0.08 -0.12 -0.23 -0.17 -0.06 -0.19 -0.04
1651 || orf19.35 || || || Predicted kinase; rat catheter, flow model, Spider biofilm induced || 1 1.19 1.34 1.04 0.43 0.23 -0.37 -0.15 0.35 0.09 -0.12 -0.40 -0.22 -0.15 0.68 -0.58 0.31
1652 || orf19.4887 || ECM21 || || Predicted regulator of endcytosis of plasma membrane proteins; fluconazole induced, alkaline induced by Rim101; repressed by caspofungin and in azole-resistant strain overexpressing MDR1; flow model, rat catheter and Spider biofilm induced || 1 1.86 2.07 1.73 1.00 0.47 -0.17 0.60 -0.04 1.05 -0.55 -0.96 -0.91 -0.01 0.26 -0.95 0.38
1653 || orf19.3554 || AAT1 || || Aspartate aminotransferase; soluble protein in hyphae; macrophage-induced protein; alkaline upregulated; amphotericin B repressed; gene used for strain identification by multilocus sequence typing; farnesol-, Hap43p-induced; GlcNAc-induced || 1 1.15 1.21 1.50 1.16 0.15 -0.59 0.40 0.33 0.09 -0.38 -0.45 -0.62 0.08 0.15 -0.88 -0.43
1654 || orf19.3097 || PDA1 || || Putative pyruvate dehydrogenase alpha chain; fluconazole-induced; protein present in exponential and stationary growth phase yeast cultures; Hap43-induced; Spider biofilm repressed || 1 1.05 0.98 0.83 0.76 0.01 0.04 0.45 0.72 0.29 0.04 -0.19 -0.42 0.01 0.14 -0.73 -0.25
1655 || orf19.3097 || PDA1 || || Putative pyruvate dehydrogenase alpha chain; fluconazole-induced; protein present in exponential and stationary growth phase yeast cultures; Hap43-induced; Spider biofilm repressed || 1 0.97 0.87 0.61 0.40 -0.12 -0.10 0.28 0.38 0.08 0.03 -0.19 -0.26 0.15 0.10 -0.64 -0.36
1656 || orf19.6561 || LAT1 || || Putative dihydrolipoamide acetyltransferase component (E2) of pyruvate dehydrogenase complex; sumoylation target; Spider biofilm repressed || 1 0.79 0.81 0.67 0.35 0.03 -0.12 0.21 0.36 0.16 0.20 -0.39 -0.59 0.29 0.32 -0.81 -0.10
1657 || orf19.5019 || || || Ortholog of C. dubliniensis CD36 : Cd36_12800, C. parapsilosis CDC317 : CPAR2_203460, Candida tenuis NRRL Y-1498 : CANTEDRAFT_94106 and Debaryomyces hansenii CBS767 : DEHA2C13948g || 1 1.01 1.09 1.32 1.42 -0.10 -0.01 -0.08 0.25 0.35 0.32 -0.31 -0.76 0.24 0.09 -1.32 -0.05
1658 || orf19.6310 || || || Has domain(s) with predicted myosin binding activity || 1 0.95 1.13 0.57 1.09 0.41 -0.20 -0.11 -0.21 -0.02 0.20 -0.32 -0.48 0.79 0.31 -0.52 -0.04
1659 || orf19.3060 || || || OPutative dolichyl-diphosphooligosaccharide-protein glycotransferase; role in protein N-linked glycosylation; Spider biofilm repressed || 1 0.73 0.90 0.63 0.81 0.69 -0.31 -0.31 -0.08 0.29 0.03 -0.22 -0.09 0.45 0.17 -0.00 -0.08
1660 || orf19.178 || || || Ortholog of C. dubliniensis CD36 : Cd36_32460, C. parapsilosis CDC317 : CPAR2_205480, Candida tenuis NRRL Y-1498 : CANTEDRAFT_115156 and Debaryomyces hansenii CBS767 : DEHA2E22154g || 1 0.77 0.73 0.63 0.46 0.57 0.13 0.14 0.06 0.12 0.10 0.17 -0.14 0.70 -0.05 0.14 -0.19
1661 || orf19.649 || || || Ortholog of C. dubliniensis CD36 : Cd36_30530, C. parapsilosis CDC317 : CPAR2_203340, Candida tenuis NRRL Y-1498 : CANTEDRAFT_117008 and Debaryomyces hansenii CBS767 : DEHA2G24244g || 1 0.85 0.97 0.47 0.62 0.46 -0.01 0.20 0.00 -0.36 0.23 -0.15 -0.37 0.68 0.12 0.03 -0.04
1662 || orf19.649 || || || Ortholog of C. dubliniensis CD36 : Cd36_30530, C. parapsilosis CDC317 : CPAR2_203340, Candida tenuis NRRL Y-1498 : CANTEDRAFT_117008 and Debaryomyces hansenii CBS767 : DEHA2G24244g || 1 0.68 0.73 0.36 0.34 0.38 -0.04 0.08 0.08 -0.18 0.20 -0.22 -0.20 0.59 0.30 0.30 0.12
1663 || orf19.7539 || INO2 || || Transcriptional activator that forms a heterodimer with Ino4p; likely regulates genes involved in phosphatidylcholine and phosphatidylinositol biosynthesis, fatty acid beta-oxidation, and peroxisome biogenesis || 1 1.63 1.72 1.33 1.98 -0.33 -0.16 0.05 0.08 -0.06 0.82 -0.65 -0.75 1.31 0.33 0.82 -0.31
1664 || orf19.7539 || INO2 || || Transcriptional activator that forms a heterodimer with Ino4p; likely regulates genes involved in phosphatidylcholine and phosphatidylinositol biosynthesis, fatty acid beta-oxidation, and peroxisome biogenesis || 1 1.95 2.01 1.49 2.29 -0.12 0.36 -0.02 0.20 0.17 1.15 -0.68 -0.25 1.60 0.69 0.79 -0.71
1665 || orf19.3823 || ZDS1 || || Nonessential protein; similar to S. cerevisiae Zds1p || 1 0.79 0.50 0.74 0.71 -0.02 -0.16 0.02 0.37 0.47 0.43 0.15 -0.07 0.57 0.41 0.19 -0.08
1666 || orf19.7473 || || || Ortholog(s) have role in endocytosis and actin cortical patch, cellular bud neck, cytoplasm localization || 1 0.46 0.79 0.50 0.75 0.15 -0.13 0.13 0.32 0.26 0.28 0.16 -0.21 0.57 0.17 0.29 -0.18
1667 || orf19.2210 || || || Protein of unknown function; Spider biofilm induced || 1 0.95 1.02 1.10 1.00 0.16 -0.33 0.38 0.14 0.69 0.23 0.65 -0.50 1.06 0.33 0.06 -0.32
1668 || orf19.5340 || || || Putative Rab GTPase activator; role in ER to Golgi vesicle-mediated transport; Spider biofilm induced || 1 0.78 0.64 0.72 0.64 -0.12 -0.12 0.50 0.13 0.10 0.50 0.02 -0.60 0.14 0.44 -0.17 0.02
1669 || orf19.2457 || || || Protein of unknown function; induced during chlamydospore formation in both C. albicans and C. dubliniensis; Spider biofilm induced || 1 1.33 1.37 1.04 1.18 -0.17 -0.67 0.63 0.55 0.58 1.47 -0.22 -0.47 0.41 0.02 -0.09 -0.26
1670 || orf19.2459 || || || Protein of unknown function; mRNA binds to She3; Hap43 repressed gene; Spider biofilm induced || 1 0.68 0.80 0.62 0.72 -0.47 -0.68 -0.06 -0.13 0.72 0.52 -0.44 -0.23 0.66 0.29 -0.12 -0.56
1671 || orf19.6456 || || || Ortholog of C. dubliniensis CD36 : Cd36_72280, C. parapsilosis CDC317 : CPAR2_703040, Candida tenuis NRRL Y-1498 : CANTEDRAFT_125842 and Debaryomyces hansenii CBS767 : DEHA2B05984g || 1 1.46 1.65 0.95 0.86 -0.21 -1.06 0.44 0.16 0.21 0.56 -0.70 -0.51 1.46 0.95 -0.27 -0.69
1672 || orf19.6456 || || || Ortholog of C. dubliniensis CD36 : Cd36_72280, C. parapsilosis CDC317 : CPAR2_703040, Candida tenuis NRRL Y-1498 : CANTEDRAFT_125842 and Debaryomyces hansenii CBS767 : DEHA2B05984g || 1 1.32 1.33 0.87 1.05 -0.85 -1.44 0.38 0.34 0.04 0.76 -0.55 -0.89 1.59 1.02 -0.28 -0.81
1673 || orf19.7042 || || || Protein of unknown function; induced by benomyl or in an azole-resistant strain overexpressing MDR1; induced by nitric oxide; Spider biofilm induced || 1 2.26 2.65 1.87 1.93 -1.16 -1.28 1.40 1.32 1.18 1.28 -0.92 -1.91 1.27 1.33 -0.70 -1.98
1674 || orf19.7042 || || || Protein of unknown function; induced by benomyl or in an azole-resistant strain overexpressing MDR1; induced by nitric oxide; Spider biofilm induced || 1 2.60 2.28 1.73 2.17 -1.86 -1.65 1.34 1.29 0.84 1.18 -0.98 -1.56 1.05 1.63 -0.51 -1.49
1675 || orf19.1356 || || || Ortholog(s) have thiosulfate sulfurtransferase activity, role in tRNA wobble position uridine thiolation and mitochondrion localization || 1 1.05 0.97 0.75 0.88 -0.55 -0.69 0.40 0.61 0.12 0.11 -0.41 -0.31 0.35 0.85 -0.17 -0.64
1676 || orf19.5848 || || || RING-type zinc finger protein; upregulated during oral infection; mutants have reduced ability to damage oral epithelial cells; Spider and flow model biofilm induced || 1 1.24 1.24 1.19 1.25 -0.26 -0.46 0.68 0.07 0.83 -0.11 -0.76 -0.84 0.61 -0.06 -0.28 -0.44
1677 || orf19.5848 || || || RING-type zinc finger protein; upregulated during oral infection; mutants have reduced ability to damage oral epithelial cells; Spider and flow model biofilm induced || 1 1.12 1.16 1.14 0.93 -0.09 -0.62 0.72 -0.06 0.82 -0.04 -0.75 -0.89 0.69 0.19 -0.06 -0.49
1678 || orf19.5848 || || || RING-type zinc finger protein; upregulated during oral infection; mutants have reduced ability to damage oral epithelial cells; Spider and flow model biofilm induced || 1 1.27 1.43 1.45 1.28 0.41 -0.54 0.81 0.19 1.03 0.03 -0.42 -0.66 0.82 0.02 0.01 -1.00
1679 || orf19.1651 || || || Ortholog of C. dubliniensis CD36 : Cd36_81960, Pichia stipitis Pignal : psti_CGOB_00163, Candida tropicalis MYA-3404 : CTRG_02378 and Candida albicans WO-1 : CAWG_02525 || 1 0.90 1.19 1.02 0.83 -0.10 -0.70 0.36 0.22 0.36 -0.27 -0.37 -0.09 0.16 0.77 -0.24 -0.39
1680 || orf19.5956 || PIN3 || || Putative SH3-domain-containing protein; predicted role in actin cytoskeleton organization; Spider biofilm repressed || 1 0.85 0.99 0.45 0.67 -0.04 -0.51 0.69 0.31 -0.07 -0.26 -0.09 -0.09 0.50 0.48 -0.14 -0.30
1681 || orf19.3711 || || || Protein with monooxygenase domains; flow model biofilm induced || 1 0.86 1.29 1.77 1.95 0.05 0.75 1.47 0.96 -0.22 -0.06 0.80 0.48 0.01 -0.32
1682 || orf19.1369 || || || Protein with predicted peptidase domains; Hap43-repressed gene || 1 0.58 0.39 0.85 1.38 -0.31 -0.75 0.54 0.63 0.41 -0.15 -0.32 -0.37 0.50 0.27 0.04 -0.10
1683 || orf19.4570 || || || Ortholog of C. dubliniensis CD36 : Cd36_42090, Debaryomyces hansenii CBS767 : DEHA2C14872g, Pichia stipitis Pignal : PICST_74821 and Spathaspora passalidarum NRRL Y-27907 : SPAPADRAFT_58607 || 1 0.85 0.74 0.96 1.29 -0.27 -0.59 0.23 0.58 -0.09 0.49 -0.61 -0.77 0.38 0.28 0.20 -0.34
1684 || orf19.1651 || || || Ortholog of C. dubliniensis CD36 : Cd36_81960, Pichia stipitis Pignal : psti_CGOB_00163, Candida tropicalis MYA-3404 : CTRG_02378 and Candida albicans WO-1 : CAWG_02525 || 1 0.54 0.58 0.71 0.92 -0.60 -0.34 0.07 0.48 -0.04 -0.10 -0.16 -0.14 -0.08 0.19 0.13 -0.18
1685 || orf19.1356 || || || Ortholog(s) have thiosulfate sulfurtransferase activity, role in tRNA wobble position uridine thiolation and mitochondrion localization || 1 0.83 0.76 1.21 1.49 -0.25 -0.35 0.28 0.48 -0.01 -0.20 -0.49 -0.57 0.13 0.41 -0.19 -0.28
1686 || orf19.7495 || || || Protein with NADPH oxidoreductase containing flavin mononucleotide (FMN) domain; induced by nitric oxide || 1 0.70 0.57 1.20 1.45 -0.30 -0.54 -0.19 -0.01 -0.23 -0.25 -0.47 -0.35 0.16 0.41 -0.14 -0.22
1687 || orf19.5680 || || || Protein with predicted hydrolase domains; similar to a universal stress protein family protein; possibly essential, disruptants not obtained by UAU1 method; Spider biofilm repressed || 1 0.39 0.35 0.63 0.64 -0.29 -0.21 -0.07 -0.01 0.04 -0.13 -0.11 -0.12 -0.07 0.09 -0.07 0.01
1688 || orf19.3710 || YHB5 || || Flavohemoglobin-related protein; not required for normal NO resistance; predicted globin/FAD-binding/NAD(P)-binding domains but lacks some conserved residues of flavohemoglobins; filament induced; rat catheter and Spider biofilm induced || 1 0.66 1.00 0.97 1.05 -1.03 -0.84 0.00 -0.45 0.24 0.60 -0.55 0.04 -0.23 0.09 -0.19 -0.32
1689 || orf19.2927 || MNN11 || || Ortholog(s) have alpha-1,2-galactosyltransferase activity, alpha-1,6-mannosyltransferase activity || 1 0.98 0.61 0.51 0.85 -0.52 -0.64 0.04 0.28 -0.10 0.80 -0.39 0.41 0.22 0.34 -0.03 -0.40
1690 || orf19.2927 || MNN11 || || Ortholog(s) have alpha-1,2-galactosyltransferase activity, alpha-1,6-mannosyltransferase activity || 1 1.12 1.04 0.89 1.17 -0.83 -0.63 0.21 0.40 -0.12 0.70 -0.19 0.23 0.23 0.16 -0.17 -0.74
1691 || orf19.5669 || || || Protein with B-cell receptor-associated protein 31-like domain; membrane-localized protein || 1 0.73 0.72 0.72 0.99 -0.49 -0.86 -0.21 0.39 0.22 0.37 -0.42 -0.44 -0.17 -0.01 -0.07 -0.90
1692 || orf19.5669 || || || Protein with B-cell receptor-associated protein 31-like domain; membrane-localized protein || 1 0.62 0.38 0.70 0.80 -0.38 -0.50 -0.16 0.23 0.05 0.46 -0.46 -0.14 -0.19 0.05 0.11 -0.24
1693 || orf19.2199 || PHO86 || || Putative endoplasmic reticulum protein; possibly adherence-induced || 1 1.60 1.17 0.95 1.95 -0.88 -0.43 0.05 0.42 0.13 0.32 -0.67 -0.13 0.18 -0.22 0.09 -0.77
1694 || orf19.4574 || || || Ortholog(s) have lipid particle localization || 1 0.76 0.55 0.96 0.75 -0.71 -0.27 0.06 -0.00 0.29 0.38 -0.57 -0.27 -0.19 -0.42 -0.10 -0.53
1695 || orf19.7049 || CYB5 || || Cytochrome b(5); ortholog of S. cerevisiae Cyb5; induced in high iron; fluconazole-induced; shows colony morphology-related gene regulation by Ssn6; mutants are viable || 1 2.14 1.67 1.69 1.75 -0.47 -0.65 0.38 1.03 0.45 0.80 -0.16 0.03 -0.39 -0.80 -0.75 -0.75
1696 || orf19.5130 || PDI1 || || Putative protein disulfide-isomerase; antigenic in human infection; soluble protein in hyphae; induced by filamentous growth; protein present in exponential and stationary growth phase yeast cultures; flow model biofilm repressed || 1 1.20 1.17 1.42 1.65 -0.68 -0.92 0.07 0.14 -0.05 0.40 0.11 -0.05 0.20 0.06 -0.24 -0.11
1697 || orf19.5130 || PDI1 || || Putative protein disulfide-isomerase; antigenic in human infection; soluble protein in hyphae; induced by filamentous growth; protein present in exponential and stationary growth phase yeast cultures; flow model biofilm repressed || 1 1.22 1.18 1.16 1.35 -1.14 -1.25 0.22 0.28 -0.38 0.37 0.16 -0.28 0.06 -0.19 -0.45 -0.34
1698 || orf19.479.2 || SEC22 || || Ortholog(s) have SNAP receptor activity and role in ER to Golgi vesicle-mediated transport, retrograde vesicle-mediated transport, Golgi to ER, vesicle fusion with Golgi apparatus || 1 0.82 0.75 0.51 0.55 -0.97 -0.65 -0.11 0.40 -0.27 0.23 0.52 -0.03 -0.10 -0.06 -0.21 0.17
1699 || orf19.4181 || SPC2 || || Signal peptidase complex component; role in ER protein translocation; transcript is induced upon filamentous growth || 1 0.71 0.52 0.59 0.63 -0.87 -0.70 0.01 0.63 -0.14 0.14 0.30 -0.05 -0.19 -0.22 -0.04 0.06
1700 || orf19.479.2 || SEC22 || || Ortholog(s) have SNAP receptor activity and role in ER to Golgi vesicle-mediated transport, retrograde vesicle-mediated transport, Golgi to ER, vesicle fusion with Golgi apparatus || 1 0.96 0.82 0.91 0.99 -0.78 -0.68 -0.35 0.54 -0.17 0.50 0.19 0.23 -0.56 0.03 -0.30 -0.03
1701 || orf19.1112 || BUD7 || || Ortholog(s) have role in Golgi to plasma membrane transport, fungal-type cell wall chitin biosynthetic process and cell division site, clathrin-coated vesicle, cytosol, exomer complex, nucleus, ribosome localization || 1 0.56 0.57 0.69 0.69 -0.35 -0.66 -0.13 0.30 0.03 0.44 0.36 0.20 -0.24 -0.04 -0.01 -0.04
1702 || orf19.479.2 || SEC22 || || Ortholog(s) have SNAP receptor activity and role in ER to Golgi vesicle-mediated transport, retrograde vesicle-mediated transport, Golgi to ER, vesicle fusion with Golgi apparatus || 1 0.75 0.40 0.76 0.65 -0.67 -0.41 -0.25 0.32 0.04 0.55 0.01 0.09 -0.08 -0.31 -0.09 0.33
1703 || orf19.3259 || || || Ortholog(s) have peptidase activity, role in protein targeting to ER, signal peptide processing and signal peptidase complex localization || 1 0.46 0.47 0.54 0.48 -0.22 -0.80 0.12 0.33 -0.30 0.19 -0.02 -0.21 0.05 -0.01 -0.14 -0.06
1704 || orf19.6434 || PEX19 || || Ortholog(s) have peroxisome membrane targeting sequence binding activity || 1 0.73 0.90 0.71 1.32 0.09 -0.35 0.13 0.69 0.08 0.75 0.03 -0.03 -0.13 -0.39 0.12 0.05
1705 || orf19.3438 || || || Ortholog(s) have chaperone binding activity, role in ER-associated ubiquitin-dependent protein catabolic process, protein folding in endoplasmic reticulum, response to unfolded protein and endoplasmic reticulum lumen localization || 1 0.59 0.55 1.15 1.23 0.02 -0.17 0.21 0.52 -0.18 0.59 -0.03 0.02 0.14 0.08 0.09 -0.16
1706 || orf19.3438 || || || Ortholog(s) have chaperone binding activity, role in ER-associated ubiquitin-dependent protein catabolic process, protein folding in endoplasmic reticulum, response to unfolded protein and endoplasmic reticulum lumen localization || 1 0.42 0.73 1.09 1.00 -0.18 -0.20 -0.07 0.36 -0.04 0.69 0.08 -0.20 -0.03 -0.28 0.38 -0.28
1707 || orf19.1317 || OSH3 || || Protein required for wild-type filamentation; has oxysterol binding protein domain and pleckstrin homology motif; overproducton suppresses cph1 homozygous null filamnetation defect; similar to S. cerevisiae Osh3p || 1 1.73 1.27 0.64 0.94 -0.78 -1.15 0.76 1.14 -0.12 0.47 0.05 -0.38 0.25 0.39 0.18 0.11
1708 || orf19.1317 || OSH3 || || Protein required for wild-type filamentation; has oxysterol binding protein domain and pleckstrin homology motif; overproducton suppresses cph1 homozygous null filamnetation defect; similar to S. cerevisiae Osh3p || 1 1.31 1.30 0.36 0.95 -1.02 -1.19 0.77 0.91 0.36 0.72 -0.13 -0.26 0.19 0.61 -0.13 -0.01
1709 || orf19.2439 || || || Fatty acid biosynthetic protein; shows colony morphology-related gene regulation by Ssn6p; protein newly produced during adaptation to the serum || 1 0.84 0.68 0.50 0.51 -0.49 -0.39 0.63 0.87 0.14 0.50 -0.02 -0.03 -0.08 -0.19 -0.48 -0.02
1710 || orf19.6510 || GRX1 || || Putative glutaredoxin; induced in low iron || 1 1.17 1.66 0.54 0.74 -0.71 -0.48 1.18 0.24 0.90 0.12 0.17 -0.49 0.31 0.23 -0.05 0.03
1711 || orf19.345 || || || Succinate semialdehyde dehydrogenase; for utilization of gamma-aminobutyrate (GABA) as a nitrogen source; part of 4-aminobutyrate and glutamate degradation pathways; rat catheter biofilm induced || 1 0.92 1.08 0.59 0.80 -0.61 -0.09 0.18 0.25 0.92 0.23 -0.16 0.07 0.37 0.16 0.21
1712 || orf19.4169 || || || Ortholog of C. dubliniensis CD36 : Cd36_40780, Candida tenuis NRRL Y-1498 : CANTEDRAFT_116553, Lodderomyces elongisporus NRLL YB-4239 : LELG_04263 and Debaryomyces hansenii CBS767 : DEHA2G21736g || 1 1.06 0.40 0.96 0.88 -0.05 -0.27 0.43 0.29 0.40 0.62 0.14 -0.46 -0.03 0.01 -0.79 -0.17
1713 || orf19.5596 || || || Ortholog(s) have ASTRA complex localization || 1 0.67 0.28 0.72 0.74 -0.28 -0.31 0.31 0.63 0.12 -0.17 0.06 -0.77 0.18 0.69 -0.42 -0.20
1714 || orf19.6317 || ADE6 || || 5-Phosphoribosylformyl glycinamidine synthetase; adenine biosynthesis; not induced in GCN response, in contrast to S. cerevisiae Ade6; protein in stationary phase yeast-form cultures; flow model and rat catheter biofilm repressed || 1 0.90 0.91 0.28 0.44 -0.12 -0.01 0.01 0.44 0.01 0.19 -0.23 -0.57 0.59 0.94 -0.59 -0.37
1715 || orf19.6317 || ADE6 || || 5-Phosphoribosylformyl glycinamidine synthetase; adenine biosynthesis; not induced in GCN response, in contrast to S. cerevisiae Ade6; protein in stationary phase yeast-form cultures; flow model and rat catheter biofilm repressed || 1 0.63 0.49 0.44 0.49 -0.49 0.09 -0.05 0.21 0.02 0.07 -0.37 -0.49 0.49 0.55 -0.81 -0.52
1716 || orf19.1946 || || || Similar to an aldose 1-epimerase-related protein; antigenic during murine systemic infection; protein present in exponential and stationary phase yeast cultures; Hap43-induced; Spider biofilm repressed || 1 0.53 0.60 0.65 0.45 -0.29 -0.22 0.00 0.00 0.25 -0.28 -0.02 -0.21 0.19 0.41 -0.44 -0.42
1717 || orf19.1651 || || || Ortholog of C. dubliniensis CD36 : Cd36_81960, Pichia stipitis Pignal : psti_CGOB_00163, Candida tropicalis MYA-3404 : CTRG_02378 and Candida albicans WO-1 : CAWG_02525 || 1 0.66 0.76 0.53 0.56 -0.46 -0.65 0.09 -0.09 0.35 0.07 0.17 -0.33 0.26 1.24 -0.84 -0.24
1718 || orf19.3555 || BUD14 || || Putative SH3-domain-containing protein; predicted role in bud-site selection; Spider biofilm induced || 1 0.47 0.62 0.43 0.23 0.49 -0.45 0.50 0.12 -0.02 -0.23 -0.25 -0.44 0.87 0.45 0.20 -0.32
1719 || orf19.1944 || GPR1 || || Plasma membrane G-protein-coupled receptor of the cAMP-PKA pathway; required for WT hyphal growth; reports differ on role in cAMP-mediated glucose signaling; Gpr1 C terminus binds Gpa2; regulates HWP1 and ECE1; flow model biofilm induced || 1 0.64 0.97 1.08 1.69 0.45 -0.18 0.58 0.14 -0.65 0.08 0.00 -0.06 1.06 0.78 0.59 0.00
1720 || orf19.4150 || || || Putative glutaredoxin; induced by nitric oxide; Spider biofilm induced || 1 0.96 1.02 0.89 1.05 0.41 0.10 0.90 0.08 -0.36 0.03 0.02 -0.03 0.86 0.86 0.66 -0.30
1721 || orf19.4150 || || || Putative glutaredoxin; induced by nitric oxide; Spider biofilm induced || 1 0.61 0.69 0.66 0.68 0.02 0.06 1.00 -0.11 -0.36 0.12 -0.44 -0.29 0.81 1.02 0.75 -0.27
1722 || orf19.4150 || || || Putative glutaredoxin; induced by nitric oxide; Spider biofilm induced || 1 0.88 0.80 0.76 0.84 -0.12 -0.32 1.33 0.16 -0.48 0.11 -0.39 -0.29 0.96 0.92 0.60 -0.35
1723 || orf19.5248 || MSO1 || || Putative secretory protein involved in S. cerevisiae sporulation; repressed during pseudohyphal growth in the presence of lysed macrophages; Hap43-repressed; Spider biofilm induced || 1 1.17 1.10 0.60 0.80 -0.13 -0.39 0.31 0.36 -0.23 -0.07 -0.13 -0.36 1.07 0.89 1.24 -0.06
1724 || orf19.5248 || MSO1 || || Putative secretory protein involved in S. cerevisiae sporulation; repressed during pseudohyphal growth in the presence of lysed macrophages; Hap43-repressed; Spider biofilm induced || 1 0.97 1.01 0.65 0.97 -0.67 -0.80 -0.00 0.23 -0.39 -0.16 -0.46 -0.42 0.88 0.91 0.93 -0.09
1725 || orf19.6608 || || || Predicted DDE superfamily endonuclease domain; repression correlates with clinical development of fluconazole resistance; Spider biofilm induced || 1 0.83 0.88 0.55 0.81 -0.13 0.10 0.39 0.26 0.37 0.18 -0.98 -0.65 1.20 0.83 0.85 0.25
1726 || orf19.4783 || || || Protein of unknown function; induced during chlamydospore formation in both C. albicans and C. dubliniensis || 1 0.47 0.28 0.88 1.31 0.07 -0.20 0.08 -0.04 0.56 -0.33 0.07 -0.06 0.93 0.49 0.29 -0.13
1727 || orf19.4264 || || || Protein of unknown function; induced during chlamydospore formation in both C. albicans and C. dubliniensis; flow model biofilm induced || 1 0.32 0.38 1.01 1.29 -0.26 0.29 0.51 0.57 0.79 -0.37 -0.27 -0.28 0.87 1.00 -0.11 -0.50
1728 || orf19.4264 || || || Protein of unknown function; induced during chlamydospore formation in both C. albicans and C. dubliniensis; flow model biofilm induced || 1 0.31 0.36 0.86 1.22 -0.71 -0.38 0.26 0.55 0.17 -0.39 -0.34 -0.24 0.57 0.76 -0.12 -0.63
1729 || orf19.4150 || || || Putative glutaredoxin; induced by nitric oxide; Spider biofilm induced || 1 0.17 0.36 1.01 1.34 -0.20 -0.01 0.48 -0.16 -0.09 0.33 -0.51 -0.27 0.44 0.88 -0.02 -0.56
1730 || orf19.4150 || || || Putative glutaredoxin; induced by nitric oxide; Spider biofilm induced || 1 0.27 0.45 1.06 1.03 -0.01 0.06 0.32 -0.05 -0.02 0.28 -0.30 -0.10 0.48 0.92 0.24 -0.57
1731 || orf19.792 || || || Ortholog(s) have protein serine/threonine kinase activity, role in activation of bipolar cell growth, protein phosphorylation, regulation of cytokinesis, regulation of mitotic sister chromatid segregation and cytosol, nucleus localization || 1 0.40 0.80 1.27 1.25 0.10 0.11 0.51 0.20 -0.18 0.65 -0.87 0.15 0.64 0.27 0.00 -0.47
1732 || orf19.1651 || || || Ortholog of C. dubliniensis CD36 : Cd36_81960, Pichia stipitis Pignal : psti_CGOB_00163, Candida tropicalis MYA-3404 : CTRG_02378 and Candida albicans WO-1 : CAWG_02525 || 1 0.71 0.25 0.52 0.84 -0.02 -0.66 -0.04 0.75 -0.00 -0.25 -0.33 -0.35 0.04 0.24 0.04 -0.03
1733 || orf19.4014 || || || Planktonic growth-induced gene || 1 0.78 1.12 0.40 0.27 -0.02 -0.77 0.17 0.61 -0.03 -0.17 0.62 -0.15 0.36 0.12 -0.05 0.36
1734 || orf19.4239 || || || Planktonic growth-induced gene || 1 1.23 0.87 0.58 0.79 -1.29 0.54 1.16 -0.27 -0.25 0.50 -0.04 0.49 0.29 0.61
1735 || orf19.4699 || || || Putative phospholipase of patatin family; similar to S. cerevisiae Tgl3p; predicted Kex2p substrate || 1 1.00 0.82 0.35 0.54 0.51 -0.31 0.50 0.56 -0.02 -0.25 0.48 0.02 0.56 0.02 0.54 0.56
1736 || orf19.3939 || || || Ortholog(s) have role in protein folding in endoplasmic reticulum and ER membrane protein complex, cell division site, cytosol, mitotic spindle pole body, nucleus localization || 1 0.59 0.72 0.52 0.56 0.17 -0.39 0.37 0.38 0.05 0.09 0.45 0.33 0.04 0.00 0.25 0.32
1737 || orf19.3183 || || || Protein with a role in insertion of tail-anchored proteins into the ER membrane; required for efficient mating, in shmoo formation and nuclear migration in the pre-zygote of S. cerevisiae; Hap43-repressed || 1 0.57 0.67 0.28 0.37 0.50 -0.53 0.14 0.48 -0.24 0.11 0.51 0.20 0.12 -0.48 0.38 0.08
1738 || orf19.3251 || ARC19 || || Putative ARP2/3 complex subunit; Hap43-induced gene; mutation confers hypersensitivity to cytochalasin D; rat catheter biofilm repressed || 1 0.49 0.38 0.18 0.26 -0.14 -0.45 0.47 0.47 -0.21 0.06 0.46 0.23 0.07 -0.16 0.31 0.21
1739 || orf19.4180 || SEC72 || || ER protein-translocation complex component; regulated by Gcn4p; repressed in response to amino acid starvation (3-aminotriazole treatment); sumoylation target || 1 0.79 0.79 -0.23 0.76 -0.21 -0.26 0.20 0.74 0.11 0.57 0.47 -0.01 -0.03 -0.04 0.01 0.03
1740 || orf19.403 || PCL2 || || Cyclin homolog; reduced expression observed upon depletion of Cln3; farnesol regulated; periodic mRNA expression, peak at cell-cycle G1/S phase; Hap43-induced; rat catheter biofilm repressed || 1 1.49 0.80 0.46 1.23 -0.75 -2.53 0.14 1.21 0.50 0.89 0.86 0.82 0.24 -0.37 0.49 0.05
1741 || orf19.403 || PCL2 || || Cyclin homolog; reduced expression observed upon depletion of Cln3; farnesol regulated; periodic mRNA expression, peak at cell-cycle G1/S phase; Hap43-induced; rat catheter biofilm repressed || 1 0.87 1.19 0.60 0.97 -0.98 -2.16 0.42 0.82 0.56 0.65 0.82 0.69 0.46 -0.47 0.09 0.09
1742 || orf19.3216 || || || Similar to Rab GTPase activators; Hap43p-induced gene || 1 0.50 0.75 0.08 0.48 -0.05 -0.62 0.01 0.09 0.13 0.22 0.44 0.63 0.24 0.01 -0.09 0.15
1743 || orf19.4723 || FAD1 || || Ortholog(s) have ATP binding, FMN adenylyltransferase activity, magnesium ion binding activity, role in FAD biosynthetic process and cytosol, nucleus localization || 1 0.85 0.90 0.42 0.85 -0.52 -0.58 0.04 0.44 0.36 -0.07 0.44 0.44 -0.45 -0.35 -0.23 0.47
1744 || orf19.6991 || PRE3 || || Putative beta-1 proteasome subunit; macrophage-induced protein; regulated by Gcn2p and Gcn4p; GlcNAc-induced protein || 1 0.53 0.50 0.36 0.54 -0.43 -0.11 -0.01 0.40 0.04 0.19 0.38 0.19 -0.28 -0.27 0.14 -0.12
1745 || orf19.2310 || || || Predicted single-stranded nucleic acid binding protein; flow model biofilm induced || 1 0.22 0.46 0.23 0.39 -0.24 -0.35 -0.10 0.19 0.28 0.30 0.28 0.35 -0.09 -0.11 0.05 -0.36
1746 || orf19.4468 || || || Putative succinate dehydrogenase; localized to the mitochondrial membrane; Hap43p-repressed gene || 1 0.53 0.47 0.48 0.59 -0.20 -0.60 0.00 0.50 0.53 0.71 0.23 0.28 -0.37 -0.58 -0.31 -0.25
1747 || orf19.1391 || || || Protein with similarity to trimeric LpxA-like enzymes; Hap43-repressed gene || 1 0.62 0.39 0.35 0.77 0.16 -0.62 -0.04 0.75 0.14 0.36 0.46 -0.13 -0.28 -0.19 -0.07 0.14
1748 || orf19.5418 || || || Ortholog(s) have role in ER to Golgi vesicle-mediated transport and endoplasmic reticulum localization || 1 0.35 -0.05 0.40 0.69 0.07 -0.38 0.42 0.77 0.14 0.55 0.19 0.09 -0.37 0.04 -0.13 0.10
1749 || orf19.2698 || || || Ortholog(s) have role in protein folding in endoplasmic reticulum and ER membrane protein complex localization || 1 0.32 0.33 0.58 0.56 -0.13 -0.16 0.00 0.46 0.21 0.62 0.52 0.52 -0.08 0.58 0.16 -0.04
1750 || orf19.7202 || || || Ortholog(s) have role in ER to Golgi vesicle-mediated transport, protein retention in ER lumen, retrograde vesicle-mediated transport, Golgi to ER and COPI-coated vesicle, ER to Golgi transport vesicle, Golgi cisterna localization || 1 0.81 0.28 0.31 0.78 -0.51 -0.68 0.09 0.99 0.17 0.90 0.51 0.14 0.21 0.18 0.01 -0.51
1751 || orf19.4879.2 || NTF2 || || Putative nuclear envelope protein; regulated by Ssn6; rat catheter biofilm repressed || 1 0.67 0.80 0.25 0.39 -0.22 -0.26 0.47 0.95 0.01 0.22 0.74 0.05 0.25 0.37 -0.55 -0.19
1752 || orf19.4879.2 || NTF2 || || Putative nuclear envelope protein; regulated by Ssn6; rat catheter biofilm repressed || 1 0.87 0.64 0.41 0.76 -0.37 -0.54 0.30 0.89 0.09 0.09 0.53 0.01 0.28 0.28 -0.40 -0.36
1753 || orf19.806 || VMA7 || || Putative subunit of the V-ATPase complex, which is involved in control of vacuolar pH; highly similar to S. cerevisiae Vma7p; interacts with phosphatidylinositol 3-kinase Vps34p || 1 0.37 0.30 0.21 0.59 -0.03 -0.44 0.33 0.83 0.02 0.14 0.52 0.17 0.06 0.05 0.13 0.11
1754 || orf19.6092 || KEL1 || || Kelch repeat domain-containing protein; localizes to sites of polarized growth; mutant colonies exhibit slightly decreased filamentation ratio; not required for buccal epithelial cell adherence or virulence in mice || 1 0.60 0.76 -0.03 0.82 0.64 -0.37 1.03 1.06 0.06 0.80 0.62 -0.02 0.69 0.39 0.75 0.06
1755 || orf19.6092 || KEL1 || || Kelch repeat domain-containing protein; localizes to sites of polarized growth; mutant colonies exhibit slightly decreased filamentation ratio; not required for buccal epithelial cell adherence or virulence in mice || 1 0.35 0.42 0.33 0.77 0.42 -0.50 0.52 0.76 0.13 0.86 0.29 -0.14 0.28 0.41 0.31 0.05
1756 || orf19.6341 || || || Ortholog(s) have 5-amino-6-(5-phosphoribosylamino)uracil reductase activity, role in riboflavin biosynthetic process and cytosol, nucleus localization || 1 0.55 0.62 0.24 0.32 0.01 -0.67 0.32 0.59 0.19 0.49 0.16 0.16 0.15 0.42 0.49 -0.11
1757 || orf19.7041 || || || Putative pre-tRNA processing protein; heterozygous null mutant exhibits hypersensitivity to parnafungin and cordycepin in the C. albicans fitness test || 1 0.71 0.64 0.29 0.69 0.13 -0.73 0.45 0.66 0.10 0.70 0.41 0.47 0.71 0.33 0.46 -0.49
1758 || orf19.1533 || || || Possible vacuolar protein; Hap43-induced gene || 1 0.35 0.31 0.54 0.74 0.30 -0.32 0.30 0.62 -0.22 0.64 0.18 0.24 0.42 0.13 0.20 0.05
1759 || orf19.2919 || MPH1 || || Protein similar to S. cerevisiae Mph1p, which is a DNA helicase involved in DNA repair; induced under hydroxyurea treatment || 1 0.85 1.04 0.38 0.54 0.19 -0.63 0.15 1.10 -0.15 0.96 0.80 0.27 0.11 0.93 -0.16 0.66
1760 || orf19.6628 || || || Protein of unknown function; rat catheter biofilm repressed || 1 0.84 0.81 1.07 0.79 0.01 -0.56 0.25 0.94 -0.08 0.40 0.87 0.16 1.04 0.53 -0.21 0.21
1761 || orf19.4830 || || || Ortholog of C. dubliniensis CD36 : Cd36_09110, C. parapsilosis CDC317 : CPAR2_803660, Candida tenuis NRRL Y-1498 : cten_CGOB_00140 and Debaryomyces hansenii CBS767 : DEHA2B12056g || 1 1.08 1.11 1.01 0.94 0.11 -1.03 0.31 1.11 0.10 0.65 0.52 -0.17 0.38 0.88 -0.46 0.17
1762 || orf19.955 || || || Protein of unknown function; Spider biofilm repressed || 1 0.37 0.72 0.69 0.75 0.00 -0.21 0.10 0.58 0.32 0.51 0.40 0.39 0.10 0.52 -0.26 0.31
1763 || orf19.4180 || SEC72 || || ER protein-translocation complex component; regulated by Gcn4p; repressed in response to amino acid starvation (3-aminotriazole treatment); sumoylation target || 1 0.83 0.90 0.71 0.69 0.05 -0.31 0.27 0.86 0.01 0.57 0.47 0.28 -0.02 0.05 0.30 0.13
1764 || orf19.7589 || || || Protein of unknown function; Hap43-repressed gene; transcript induced by elevated CO2 || 1 0.83 0.99 0.82 0.78 -0.03 -0.55 0.51 1.16 0.24 0.74 0.53 0.30 0.12 0.16 0.07 0.31
1765 || orf19.5817 || || || Ortholog(s) have Rab guanyl-nucleotide exchange factor activity, role in ER to Golgi vesicle-mediated transport, intra-Golgi vesicle-mediated transport and TRAPP complex, cis-Golgi network membrane, cytosol, nucleus localization || 1 0.91 0.86 0.60 1.01 -0.19 -0.58 0.63 1.12 0.42 0.99 0.81 0.62 0.15 0.20 0.19 0.33
1766 || orf19.5934 || || || Ortholog(s) have DNA topoisomerase type I activity || 1 0.56 0.81 0.56 0.87 -0.30 -0.85 0.25 0.83 0.37 1.00 0.46 0.25 0.17 0.03 -0.35 -0.08
1767 || orf19.5691 || CDC11 || || Septin; cell and hyphal morphology, agar-invasive growth, full virulence and kidney tissue invasion in mouse, but not kidney colonization, immunogenicity; hyphal and cell-cycle-regulated phosphorylation; rat catheter biofilm repressed || 1 0.84 0.72 0.61 0.74 -0.04 -0.87 0.40 0.99 0.36 1.29 0.52 0.22 0.44 0.36 0.02 0.33
1768 || orf19.5934 || || || Ortholog(s) have DNA topoisomerase type I activity || 1 0.61 0.44 0.89 0.79 0.10 -0.79 0.23 0.76 0.58 1.09 0.47 0.50 0.46 0.47 -0.14 0.30
1769 || orf19.6901 || || || Ortholog(s) have exoribonuclease activator activity, m7G(5')pppN diphosphatase activity || 1 0.28 0.23 0.55 0.27 -0.08 -0.40 0.24 0.34 0.43 0.60 0.17 -0.05 0.28 0.31 -0.06 0.16
1770 || orf19.3135 || || || Ortholog(s) have protein binding, bridging activity and role in ER-associated ubiquitin-dependent protein catabolic process, lipid particle organization || 1 0.66 0.76 0.67 0.61 -0.07 -0.29 0.23 0.55 0.63 0.30 0.23 0.04 0.18 0.16 -0.19 -0.05
1771 || orf19.4169 || || || Ortholog of C. dubliniensis CD36 : Cd36_40780, Candida tenuis NRRL Y-1498 : CANTEDRAFT_116553, Lodderomyces elongisporus NRLL YB-4239 : LELG_04263 and Debaryomyces hansenii CBS767 : DEHA2G21736g || 1 0.91 1.07 0.67 1.29 0.57 -0.42 0.33 0.89 -0.04 0.82 0.18 -0.22 0.11 0.50 -0.08 -0.21
1772 || orf19.2919 || MPH1 || || Protein similar to S. cerevisiae Mph1p, which is a DNA helicase involved in DNA repair; induced under hydroxyurea treatment || 1 0.66 0.20 0.43 0.66 0.45 -0.38 0.35 1.08 0.04 0.82 0.16 0.34 0.32 0.80 -0.12 0.62
1773 || orf19.485 || || || Ortholog(s) have structural constituent of cytoskeleton activity || 1 0.09 0.09 0.38 0.66 0.01 -0.25 0.04 0.46 0.10 0.28 0.22 0.18 -0.04 0.18 -0.19 0.48
1774 || orf19.955 || || || Protein of unknown function; Spider biofilm repressed || 1 0.34 0.31 0.59 0.77 0.09 -0.34 0.16 0.80 -0.16 0.07 0.24 0.26 0.07 0.54 -0.46 0.26
1775 || orf19.6553 || || || Membrane-localized protein of unknown function; possibly secreted; fluconazole-induced || 1 0.70 0.40 0.59 0.77 0.06 -0.41 0.02 0.31 0.32 -0.15 0.22 0.13 0.25 -0.00 0.00 0.27
1776 || orf19.5947 || SEC7 || || Putative guanine nucleotide exchange factor (GEF); mutation confers hypersensitivity to Brefeldin A; caspofungin repressed || 1 0.49 0.18 0.59 0.62 -0.04 -0.15 0.24 0.44 0.21 0.07 -0.02 0.23 0.33 0.34 -0.19 0.02
1777 || orf19.5056 || || || Ortholog(s) have enzyme regulator activity, mitotic anaphase-promoting complex activity || 1 0.51 0.34 0.75 0.83 0.04 -0.19 0.25 0.15 0.03 0.28 -0.28 0.27 0.45 0.10 -0.17 0.19
1778 || orf19.3639 || || || Ortholog(s) have alkylbase DNA N-glycosylase activity and role in DNA dealkylation involved in DNA repair, base-excision repair, AP site formation || 1 0.81 0.70 0.96 1.32 -0.52 -0.30 0.04 0.08 -0.18 0.05 0.12 0.55 0.23 0.45 0.09 0.39
1779 || orf19.4201 || NHX1 || || Protein similar to S. cerevisiae Nhx1p, which is an Na+/H+ exchanger required for intracellular sequestration of Na+ || 1 0.44 0.35 0.51 0.82 -0.09 -0.07 0.09 0.17 0.01 0.06 0.25 0.63 -0.01 0.30 0.19 0.37
1780 || orf19.1484 || || || Ortholog of S, cerevisiae Spc24; a component of the conserved kinetochore-associated Ndc80 complex involved in chromosome segregation, spindle checkpoint activity and kinetochore clustering; Hap43-induced gene || 1 0.28 0.47 0.78 0.93 0.19 -0.12 -0.16 0.33 -0.32 0.24 0.33 0.55 0.12 0.47 -0.14 0.65
1781 || orf19.4904 || || || Ortholog(s) have nucleosome binding activity, role in chromatin silencing at telomere, histone exchange and Swr1 complex, cytosol, nuclear chromosome, telomeric region localization || 1 0.40 0.28 0.44 0.59 0.02 -0.28 -0.20 0.32 0.01 0.18 0.42 0.22 0.27 0.33 0.08 0.10
1782 || orf19.4201 || NHX1 || || Protein similar to S. cerevisiae Nhx1p, which is an Na+/H+ exchanger required for intracellular sequestration of Na+ || 1 0.68 0.67 0.34 0.95 0.28 -0.27 -0.00 0.14 -0.27 0.00 0.47 0.11 0.00 0.25 0.21 0.47
1783 || orf19.3572 || || || Ortholog of C. dubliniensis CD36 : Cd36_19880, Candida tenuis NRRL Y-1498 : CANTEDRAFT_117672, Debaryomyces hansenii CBS767 : DEHA2D11154g and Pichia stipitis Pignal : PICST_59570 || 1 0.56 0.42 0.54 0.53 0.17 -0.27 0.02 0.15 -0.09 0.61 0.28 0.31 0.49 0.50 0.10 0.49
1784 || orf19.4781 || GRP1 || || Protein similar to dihydroflavonol-4-reductases || 1 0.55 0.38 0.65 0.43 0.30 -0.68 0.21 0.49 0.03 0.12 0.21 0.59 0.56 0.15 -0.00 0.50
1785 || orf19.1446 || CLB2 || || B-type mitotic cyclin (cyclin-dependent protein kinase regulatory subunit); essential; required for wild-type mitotic exit; role in cell polarization; interacts with catalytic subunit Cdk1; Spider biofilm repressed || 1 0.91 0.20 0.31 0.55 -0.05 -0.47 0.53 0.91 0.89 0.41 0.38 0.50 0.62 0.00 0.15 0.23
1786 || orf19.2964 || || || Ortholog(s) have DNA translocase activity || 1 0.78 0.07 0.47 0.53 -0.25 0.08 0.45 0.49 0.50 0.38 0.44 0.17 0.50 0.38 -0.14 0.12
1787 || orf19.3622 || ANP1 || || Putative mannosyltransferase of Golgi; member of Mnn9p family; similar to S. cerevisiae Anp1p; fungal-specific (no human or murine homolog) || 1 0.70 -0.03 0.48 0.66 -0.31 0.15 0.38 0.47 0.31 0.34 0.65 0.21 0.34 0.10 0.15 0.15
1788 || orf19.1803 || CDC43 || || Beta subunit of heterodimeric protein geranylgeranyltransferase type I; GGTase I enzyme binds zinc, is Mg-dependent; Cdc42p is GGTase I substrate || 1 0.44 0.38 0.35 0.47 0.01 -0.10 0.34 0.59 0.65 0.99 0.32 0.34 0.48 -0.02 -0.14 0.01
1789 || orf19.1447 || || || Ortholog of C. dubliniensis CD36 : Cd36_16290, C. parapsilosis CDC317 : CPAR2_214050, Candida tenuis NRRL Y-1498 : CANTEDRAFT_92180 and Debaryomyces hansenii CBS767 : DEHA2A01738g || 1 0.75 0.88 1.02 0.20 0.16 -0.19 0.45 0.60 0.39 1.29 0.50 0.72 0.46 0.22 -0.73 -0.29
1790 || orf19.7631 || SLD5 || || Putative GINS complex subunit; cell-cycle regulated periodic mRNA expression || 1 0.22 0.68 0.59 0.14 -0.05 0.00 0.25 0.41 0.25 0.46 0.41 0.43 0.64 -0.22 -0.26 0.15
1791 || orf19.2333 || || || Ortholog(s) have role in retrograde transport, endosome to Golgi and cytosol, late endosome, nucleus localization || 1 1.01 0.97 0.64 -0.17 -0.19 -0.15 0.55 0.71 0.71 0.45 0.24 0.05 0.42 -0.12 -0.48 -0.21
1792 || orf19.2333 || || || Ortholog(s) have role in retrograde transport, endosome to Golgi and cytosol, late endosome, nucleus localization || 1 0.45 0.62 0.84 0.04 -0.17 -0.24 0.09 0.38 0.73 0.30 -0.24 0.02 0.34 -0.12 -0.55 0.03
1793 || orf19.2016 || ERG28 || || Ortholog(s) have protein binding, bridging activity, role in ergosterol biosynthetic process and endoplasmic reticulum membrane localization || 1 0.31 0.33 0.27 0.12 -0.01 -0.44 0.30 0.33 0.55 0.15 -0.02 0.05 0.20 -0.13 -0.21 0.25
1794 || orf19.281 || || || Ortholog of C. dubliniensis CD36 : Cd36_82880, C. parapsilosis CDC317 : CPAR2_102370, Candida tenuis NRRL Y-1498 : CANTEDRAFT_118463 and Pichia stipitis Pignal : PICST_32241 || 1 0.70 0.67 0.02 0.20 0.18 -0.11 0.15 0.36 0.14 -0.28 -0.28 -0.32 0.48 -0.60 0.05 0.37
1795 || orf19.867 || || || Ortholog(s) have superoxide-generating NADPH oxidase activity, role in apoptotic process, regulation of actin cytoskeleton organization and perinuclear endoplasmic reticulum, ribosome localization || 1 0.71 0.63 0.30 0.30 0.21 -0.06 0.35 0.32 0.14 0.00 0.22 -0.54 0.05 -0.34 -0.16 0.01
1796 || orf19.5840 || || || Ortholog(s) have cytoplasm, mating projection tip localization || 1 1.34 1.08 0.68 0.52 0.61 -0.12 0.49 0.83 -0.23 -0.83 0.38 -0.42 0.20 -0.38 -0.15 0.00
1797 || orf19.980 || || || Ortholog(s) have inositol heptakisphosphate kinase activity, inositol hexakisphosphate 1-kinase activity, inositol hexakisphosphate 3-kinase activity, inositol hexakisphosphate 4-kinase activity, inositol hexakisphosphate 6-kinase activity || 1 0.60 0.58 0.08 0.29 0.16 0.02 0.13 0.03 0.05 -0.45 0.26 -0.18 0.31 -0.14 -0.31 0.14
1798 || orf19.2786 || || || Ortholog(s) have AP-2 adaptor complex, cellular bud neck localization || 1 0.36 0.54 0.14 0.22 0.37 -0.15 0.06 0.09 0.04 -0.49 0.03 -0.31 0.33 -0.04 -0.33 0.08
1799 || orf19.4290 || TRR1 || || Thioredoxin reductase; regulated by Tsa1/Tsa1B, Hap43; induced by nitric oxide, peroxide; oxidative stress-induce via Cap1; induced by human neutrophils; stationary phase enriched protein || 1 0.74 0.52 0.01 0.14 0.39 -0.30 0.27 0.21 0.05 -0.22 0.20 -0.28 0.36 0.14 -0.44 0.02
1800 || orf19.6198.1 || || || Ortholog of S. cerevisiae : YIL156W-B, C. glabrata CBS138 : CAGL0H06732g, C. dubliniensis CD36 : Cd36_06600, C. parapsilosis CDC317 : CPAR2_208850 and Candida tenuis NRRL Y-1498 : CANTEDRAFT_116509 || 1 1.00 1.00 0.53 0.35 0.45 -0.24 0.29 0.53 0.46 -0.17 0.41 0.09 0.71 0.47 -0.18 0.31
1801 || orf19.6771 || UBI4 || || Ubiquitin precursor (polyubiquitin) contains 3 tandem repeats of the ubiquitin peptide that are processed to individual units; transcript induced by stress; mRNA in yeast and mycelia at similar abundance; Spider biofilm induced || 1 1.58 1.57 0.91 0.15 0.20 1.05 0.20 0.43 -0.09 0.34 -0.29 1.29 0.80 -0.54 -0.37
1802 || orf19.6056 || || || Ortholog(s) have phosphatase activity, role in dephosphorylation and cytosol, nucleus localization || 1 1.43 1.36 0.74 0.51 0.20 0.96 0.94 0.23 0.59 -0.41 0.28 -0.04 0.49 0.20 -0.47 0.33
1803 || orf19.6056 || || || Ortholog(s) have phosphatase activity, role in dephosphorylation and cytosol, nucleus localization || 1 1.26 1.19 1.01 0.67 0.11 0.83 0.65 0.16 0.61 -0.20 0.10 0.17 0.22 0.28 -0.62 0.42
1804 || orf19.3156 || || || Protein of unknown function; induced by Mnl1 under weak acid stress || 1 0.98 1.03 0.77 0.35 0.10 0.46 0.18 0.48 0.43 0.16 0.23 -0.14 0.52 0.07 -0.26 0.22
1805 || orf19.7199 || || || Ortholog(s) have TRC complex, nucleus localization || 1 1.29 1.23 1.19 1.20 -0.30 0.52 0.61 0.63 0.34 -0.42 0.31 0.37 1.01 0.49 -0.15 0.24
1806 || orf19.6809 || || || Putative phosphomutase-like protein; protein present in exponential and stationary growth phase yeast; Hap43-repressed; Spider biofilm repressed || 1 0.89 0.92 0.67 0.81 -0.11 0.46 0.79 0.62 0.63 -0.65 0.55 0.35 0.38 0.61 -0.69 0.51
1807 || orf19.3721 || || || Protein of unknown function; Spider biofilm induced || 1 0.22 0.86 0.55 0.43 0.09 -0.17 1.11 0.23 0.68 -0.34 0.39 0.28 0.37 -0.03 -0.11 -0.03
1808 || orf19.4513 || || || Protein of unknown function; mutants are viable; rat catheter and Spider biofilm induced || 1 0.78 0.77 0.30 0.39 -0.04 -0.15 1.60 0.76 0.92 -0.59 -0.06 -0.12 0.38 0.40 -0.24 0.55
1809 || orf19.4768 || || || Protein of unknown function; Spider biofilm induced || 1 0.71 0.23 0.54 0.15 0.11 0.11 1.09 0.24 0.56 0.05 0.30 -0.12 0.11 0.44 0.17 0.15
1810 || orf19.4305.1 || || || Ortholog(s) have RNA binding activity, role in mRNA splicing, via spliceosome and U4/U6 x U5 tri-snRNP complex, U6 snRNP, nucleolus localization || 1 0.38 0.03 0.32 0.38 -0.01 0.10 0.32 0.35 0.73 -0.23 -0.25 -0.10 0.08 0.41 -0.43 -0.04
1811 || orf19.2284 || || || Protein with an FMN-binding domain; Hap43-repressed; flow model biofilm induced || 1 0.48 0.45 0.34 0.49 -0.07 -0.23 0.59 0.05 0.86 -0.69 -0.26 0.01 -0.03 -0.16 -0.52 0.24
1812 || orf19.3142 || || || Ortholog of C. dubliniensis CD36 : Cd36_46140, C. parapsilosis CDC317 : CPAR2_501210, Candida tenuis NRRL Y-1498 : CANTEDRAFT_97195 and Debaryomyces hansenii CBS767 : DEHA2E08800g || 1 0.56 0.50 0.38 0.49 -0.14 -0.55 0.79 0.12 1.00 -0.78 -0.70 -0.25 0.57 -0.16 -0.39 -0.03
1813 || orf19.3142 || || || Ortholog of C. dubliniensis CD36 : Cd36_46140, C. parapsilosis CDC317 : CPAR2_501210, Candida tenuis NRRL Y-1498 : CANTEDRAFT_97195 and Debaryomyces hansenii CBS767 : DEHA2E08800g || 1 1.38 0.87 0.72 1.34 0.07 -0.25 0.67 0.58 1.58 -0.69 -0.63 -0.17 0.57 0.28 -0.59 -0.19
1814 || orf19.56 || ARG2 || || Putative enzyme of arginine biosynthesis; transcription of genes of arginine biosynthesis pathway, except for ARG2, is induced upon phagocytosis by macrophage || 1 0.64 0.45 0.78 0.67 0.13 -0.01 0.26 0.04 0.81 -0.39 0.23 -0.01 0.08 0.00 -0.38 0.23
1815 || orf19.56 || ARG2 || || Putative enzyme of arginine biosynthesis; transcription of genes of arginine biosynthesis pathway, except for ARG2, is induced upon phagocytosis by macrophage || 1 0.59 0.59 0.75 0.65 0.18 -0.20 0.10 0.07 0.85 -0.39 -0.04 -0.30 -0.23 -0.20 -0.78 -0.03
1816 || orf19.6809 || || || Putative phosphomutase-like protein; protein present in exponential and stationary growth phase yeast; Hap43-repressed; Spider biofilm repressed || 1 0.79 0.75 0.13 0.14 -0.37 -0.25 0.86 0.50 0.17 -0.66 0.44 -0.37 0.17 0.34 -1.00 0.11
1817 || orf19.7578 || || || Ortholog(s) have oligosaccharide binding activity, role in ER-associated ubiquitin-dependent protein catabolic process and Hrd1p ubiquitin ligase ERAD-L complex, luminal surveillance complex localization || 1 0.66 0.41 0.29 0.17 -0.11 -0.31 0.17 0.18 -0.12 -0.33 -0.46 -0.50 -0.08 -0.04 -0.12 -0.26
1818 || orf19.4887 || ECM21 || || Predicted regulator of endcytosis of plasma membrane proteins; fluconazole induced, alkaline induced by Rim101; repressed by caspofungin and in azole-resistant strain overexpressing MDR1; flow model, rat catheter and Spider biofilm induced || 1 1.63 1.73 1.11 0.34 0.22 -0.91 0.52 -0.13 0.52 -0.86 -1.18 -1.62 -0.22 -0.33 -0.99 -0.27
1819 || orf19.4450.1 || || || Protein conserved among the CTG-clade; 2 adjacent upstream SRE-1 elements; highly up-regulated in cecum-grown cells in a Cph2-dependent manner; Hap43-repressed; rat catheter, Spider and flow model biofilm induced || 1 2.99 3.09 2.33 -0.73 -0.68 -0.65 1.40 0.86 1.53 -0.88 -2.08 -2.33 0.37 -0.02 -0.79 -1.51
1820 || orf19.4450.1 || || || Protein conserved among the CTG-clade; 2 adjacent upstream SRE-1 elements; highly up-regulated in cecum-grown cells in a Cph2-dependent manner; Hap43-repressed; rat catheter, Spider and flow model biofilm induced || 1 3.03 3.24 3.08 0.08 -0.65 -0.21 1.66 1.14 1.74 -0.54 -1.92 -1.91 0.49 0.23 -0.79 -0.99
1821 || orf19.5114 || || || Sorting nexin; role in maintaining late-Golgi resident enzymes in their proper location by recycling molecules from the prevacuolar compartment; Spider biofilm induced || 1 1.22 1.22 0.97 0.51 0.16 -0.27 -0.06 0.35 0.88 -0.12 -0.37 -0.85 -0.46 -0.36 -0.56 -0.67
1822 || orf19.4383 || || || Ortholog(s) have DNA 5'-adenosine monophosphate hydrolase activity, mismatched DNA binding, zinc ion binding activity, role in cellular response to DNA damage stimulus and cytosol, nucleus localization || 1 0.54 0.48 0.83 0.36 -0.05 0.50 0.57 -0.00 0.49 -0.00 -0.74 -0.42 -0.17 -0.12 -0.50 -0.11
1823 || orf19.4383 || || || Ortholog(s) have DNA 5'-adenosine monophosphate hydrolase activity, mismatched DNA binding, zinc ion binding activity, role in cellular response to DNA damage stimulus and cytosol, nucleus localization || 1 1.04 0.84 0.81 0.29 -0.56 0.94 0.40 0.37 0.93 0.39 -0.75 0.10 0.36 0.18 -0.54 0.02
1824 || orf19.6510 || GRX1 || || Putative glutaredoxin; induced in low iron || 1 1.15 1.51 0.44 0.39 0.20 0.46 0.97 -0.42 0.56 0.43 -0.69 0.19 0.13 -0.32 -0.26 -0.04
1825 || orf19.1617 || || || Protein similar to S. cerevisiae Ydr282cp; transposon mutation affects filamentous growth; Hap43p-repressed gene || 1 0.54 0.55 0.40 0.05 0.37 0.33 0.37 0.14 0.73 0.17 -0.31 -0.47 0.29 0.61 0.02 0.09
1826 || orf19.1668 || || || Protein of unknown function; expression downregulated in an ssr1 null mutant || 1 0.70 0.53 0.57 0.08 0.49 0.14 0.08 0.29 0.63 0.28 -0.77 -0.52 -0.06 0.57 -0.69 0.10
1827 || orf19.3163 || || || Ortholog of C. dubliniensis CD36 : Cd36_51910, C. parapsilosis CDC317 : CPAR2_101650, Candida tenuis NRRL Y-1498 : CANTEDRAFT_94797 and Debaryomyces hansenii CBS767 : DEHA2D06578g || 1 0.18 1.47 0.91 0.62 -0.12 -0.24 0.12 -0.04 -0.22 -0.18 -0.22 -0.41 -0.10 -0.09 -0.16 -0.06
1828 || orf19.2914 || || || Ortholog of C. dubliniensis CD36 : Cd36_45760, C. parapsilosis CDC317 : CPAR2_401920, Candida tenuis NRRL Y-1498 : CANTEDRAFT_126814 and Debaryomyces hansenii CBS767 : DEHA2D16742g || 1 0.71 0.66 0.59 0.62 0.03 -0.02 -0.02 -0.02 0.28 -0.01 0.16 -0.41 0.05 -0.47 0.37 0.03
1829 || orf19.819 || || || Ortholog(s) have role in lipoate biosynthetic process and mitochondrion localization || 1 0.82 -0.21 0.40 0.35 -0.40 -0.02 0.72 0.71 0.96 0.70 0.21 -0.43 -0.15 -0.22 -0.50 -0.69
1830 || orf19.6231 || MRPL19 || || Putative ribosomal protein; induced upon adherence to polystyrene; Spider biofilm repressed || 1 0.82 -0.11 0.61 0.26 0.15 0.14 0.61 0.68 0.85 0.39 0.54 0.14 0.23 -0.22 0.10 -0.39
1831 || orf19.6866 || || || Putative U1-70K component of the U1 snRNP, involved in splicing; ortholog of S. cerevisiae SNP1; downregulated upon adherence to polystyrene || 1 0.28 0.05 0.19 0.37 0.14 -0.01 0.54 0.37 0.41 0.40 0.20 -0.05 0.15 0.09 0.17 -0.47
1832 || orf19.644 || HGT9 || || Putative glucose transporter of the major facilitator superfamily; the C. albicans glucose transporter family comprises 20 members; 12 probable membrane-spanning segments; induced at low (0.2%, compared to 2%) glucose in rich media; intron || 1 0.59 0.60 0.54 0.90 0.16 0.61 0.25 1.93 1.42 -0.18 0.45 -0.93 0.40 -0.06 -1.63
1833 || orf19.3792 || || || Ortholog(s) have role in cytoplasmic mRNA processing body assembly, deadenylation-dependent decapping of nuclear-transcribed mRNA, formation of translation preinitiation complex, negative regulation of translational initiation || 1 0.94 0.22 -0.07 0.64 0.05 0.09 0.16 0.54 1.02 0.12 -0.01 0.31 0.33 0.02 -0.05 -0.17
1834 || orf19.295 || || || Ortholog of C. dubliniensis CD36 : Cd36_82970, Lodderomyces elongisporus NRLL YB-4239 : LELG_02117, Debaryomyces hansenii CBS767 : DEHA2G01012g and Candida lusitaniae ATCC 42720 : CLUG_03529 || 1 0.56 0.31 0.00 0.12 0.26 0.05 0.34 0.64 0.20 0.05 0.10 0.14 0.10 -0.14 0.21 0.22
1835 || orf19.6035 || || || Protein of unknown function; repressed by nitric oxide || 1 1.12 1.18 0.05 -0.11 0.01 -0.39 0.66 1.13 -0.19 0.55 0.57 -0.12 -0.40 -0.43 -0.03 -0.52
1836 || orf19.92 || || || Protein with a predicted thioredoxin-like domain; Hap43-repressed; induced by prostaglandins || 1 0.92 0.95 0.74 0.67 0.30 -0.06 0.68 1.03 0.63 0.61 0.37 0.35 -0.49 -0.31 -0.01 -0.07
1837 || orf19.3577.1 || || || Ortholog(s) have mitochondrial intermembrane space localization || 1 0.85 1.01 0.28 0.32 0.07 0.36 0.58 1.07 0.47 0.84 0.44 0.58 -0.33 0.12 0.47 0.31
1838 || orf19.6585 || || || Ortholog(s) have mitochondrion localization || 1 1.20 1.34 0.49 0.53 -0.41 -0.37 1.10 1.42 0.69 1.31 1.26 1.08 -0.16 -0.08 0.63 0.13
1839 || orf19.446.1 || || || Protein with a NADH-ubiquinone oxidoreductase B18 subunit domain; gene has intron || 1 0.66 0.73 -0.41 -0.21 -0.26 -0.53 1.18 1.19 0.26 0.60 1.02 0.31 0.28 0.31 0.32 -0.22
1840 || orf19.2570 || MCI4 || || Putative NADH-ubiquinone dehydrogenase; Hap43p-repressed gene || 1 1.21 1.24 -0.23 0.62 0.51 0.16 1.33 1.73 0.96 1.02 0.91 0.24 0.75 0.12 0.54 -0.50
1841 || orf19.3577.1 || || || Ortholog(s) have mitochondrial intermembrane space localization || 1 0.88 1.24 0.19 0.09 0.57 0.05 1.04 0.95 0.49 0.58 0.84 0.23 0.07 -0.01 0.60 -0.84
1842 || orf19.3366.1 || || || Protein of unknown function; Hap43-repressed gene || 1 1.26 1.34 -0.25 -0.12 0.54 -0.27 1.54 1.77 0.24 0.43 1.54 0.07 0.27 -0.36 0.72 -0.53
1843 || orf19.3366.1 || || || Protein of unknown function; Hap43-repressed gene || 1 1.68 1.75 0.24 0.27 0.84 -0.20 1.33 2.04 0.44 0.61 1.50 0.14 0.45 -0.20 0.81 -0.06
1844 || orf19.6035 || || || Protein of unknown function; repressed by nitric oxide || 1 1.27 1.39 0.23 0.17 0.38 -0.13 0.90 1.54 0.34 0.54 0.96 0.47 -0.23 0.03 0.32 -0.31
1845 || orf19.5077 || || || Protein of unknown function; Hap43-repressed gene; repressed by nitric oxide || 1 0.94 0.94 0.24 -0.05 0.14 0.23 1.09 1.19 0.43 0.68 0.76 0.35 0.10 -0.14 0.51 -0.05
1846 || orf19.3223.1 || || || Putative 12kDa subunit of mitochondrial NADH-ubiquinone oxidoreductase; gene has intron || 1 1.17 1.03 0.08 0.26 -0.36 -0.28 1.48 1.58 0.61 0.94 0.77 0.12 -0.29 0.08 -0.28 -0.44
1847 || orf19.3223.1 || || || Putative 12kDa subunit of mitochondrial NADH-ubiquinone oxidoreductase; gene has intron || 1 1.00 1.09 0.09 0.14 -0.44 -0.25 1.18 1.39 0.81 0.94 0.72 0.12 -0.09 -0.05 -0.23 -0.19
1848 || orf19.3290 || || || Plasma membrane-localized protein; repressed by nitric oxide; Hap43p-repressed gene || 1 0.85 0.71 0.10 0.03 -0.00 -0.18 1.17 1.37 0.49 0.66 0.55 0.09 0.22 0.23 0.22 0.08
1849 || orf19.3611 || || || Protein of unknown function; Hap43-repressed gene; repressed by nitric oxide || 1 0.73 0.66 0.03 0.01 -0.13 -0.26 0.94 1.29 0.28 0.53 0.43 0.19 0.09 0.43 0.19 -0.10
1850 || orf19.3290 || || || Plasma membrane-localized protein; repressed by nitric oxide; Hap43p-repressed gene || 1 0.72 0.72 -0.01 0.09 -0.19 -0.21 1.10 1.34 0.33 0.56 0.51 -0.27 0.23 0.27 0.07 -0.60
1851 || orf19.5629 || QCR7 || || Putative ubiquinol-cytochrome-c reductase, subunit 7; Hap43p-repressed gene || 1 1.29 1.28 -0.26 0.10 -0.28 -0.75 1.59 1.70 0.46 0.69 0.77 -0.19 0.04 0.37 0.49 -0.32
1852 || orf19.5629 || QCR7 || || Putative ubiquinol-cytochrome-c reductase, subunit 7; Hap43p-repressed gene || 1 1.71 1.65 -0.09 0.07 -0.02 -0.87 1.80 1.93 0.17 0.59 0.95 -0.16 0.40 0.02 0.49 -0.86
1853 || orf19.2707.1 || QCR9 || || Putative ubiquinol cytochrome c reductase; shows colony morphology-related gene regulation by Ssn6p || 1 1.34 1.26 0.32 0.52 0.04 -0.34 1.44 1.54 0.49 0.33 0.82 0.05 0.34 -0.07 0.26 -0.31
1854 || orf19.2707.1 || QCR9 || || Putative ubiquinol cytochrome c reductase; shows colony morphology-related gene regulation by Ssn6p || 1 1.16 1.14 0.41 0.66 -0.18 -0.51 1.36 1.49 0.44 0.36 0.80 -0.13 0.24 -0.29 -0.00 -0.42
1855 || orf19.446.2 || || || Protein with a NADH-ubiquinone oxidoreductase B18 subunit domain; gene has intron || 1 0.91 1.04 0.14 0.01 0.28 -0.23 1.07 1.23 0.49 0.62 0.45 -0.16 0.51 -0.07 0.20 -0.70
1856 || orf19.4759 || COX5 || || Cytochrome oxidase subunit V; putative upstream CCAAT box regulatory element; macrophage/pseudohyphal-induced; repressed by nitric oxide; intron in 5'-UTR; Hap43p-dependent repression in low iron medium || 1 1.17 1.34 0.47 0.12 0.28 -0.22 1.41 1.47 0.69 0.69 0.17 -0.32 0.50 0.10 0.03 -0.61
1857 || orf19.2821 || || || Protein of unknown function; Hap43-repressed gene; repressed by nitric oxide || 1 0.59 0.67 -0.03 -0.17 -0.23 -0.29 0.90 1.01 0.67 0.72 0.17 0.15 -0.09 -0.11 0.45 -0.17
1858 || orf19.4758 || || || Putative reductase or dehydrogenase; Hap43-repressed gene; alkaline repressed || 1 0.81 0.66 -0.04 -0.03 -0.13 -0.04 0.92 1.04 0.56 0.75 -0.02 0.25 -0.23 -0.18 0.70 -0.31
1859 || orf19.4758 || || || Putative reductase or dehydrogenase; Hap43-repressed gene; alkaline repressed || 1 0.54 0.44 0.10 -0.08 -0.20 0.10 0.57 0.61 0.34 0.50 -0.13 0.22 -0.48 -0.27 0.40 -0.17
1860 || orf19.2782 || || || Ortholog(s) have disulfide oxidoreductase activity, role in cellular response to oxidative stress, response to osmotic stress and mitochondrial matrix localization || 1 0.51 0.79 0.01 -0.06 -0.33 -0.70 0.74 1.06 0.15 0.47 0.70 0.33 -0.45 -0.13 0.25 -0.10
1861 || orf19.2782 || || || Ortholog(s) have disulfide oxidoreductase activity, role in cellular response to oxidative stress, response to osmotic stress and mitochondrial matrix localization || 1 0.17 0.47 -0.17 -0.34 -0.44 -0.44 0.59 0.85 0.17 0.43 0.66 0.38 -0.70 -0.14 0.19 -0.13
1862 || orf19.2821 || || || Protein of unknown function; Hap43-repressed gene; repressed by nitric oxide || 1 0.56 0.64 -0.95 -0.79 -0.35 -0.65 0.88 0.90 -0.07 0.35 0.07 -0.53 -0.05 -0.82 0.38 -0.51
1863 || orf19.5825.1 || || || Ortholog(s) have role in ER to Golgi vesicle-mediated transport and ER to Golgi transport vesicle, endoplasmic reticulum membrane, integral to Golgi membrane localization || 1 0.93 0.50 -0.10 -0.09 0.26 -0.46 0.48 0.59 -0.14 -0.30 0.30 -0.26 0.42 -0.31 0.07 -0.58
1864 || orf19.2439 || || || Fatty acid biosynthetic protein; shows colony morphology-related gene regulation by Ssn6p; protein newly produced during adaptation to the serum || 1 0.86 0.81 -0.22 0.17 -0.06 -0.44 0.91 0.87 -0.27 -0.08 0.25 -0.41 0.17 -0.45 -0.27 -0.41
1865 || orf19.446.2 || || || Protein with a NADH-ubiquinone oxidoreductase B18 subunit domain; gene has intron || 1 0.81 0.81 -0.66 -0.60 -0.05 -0.82 1.29 1.44 0.29 0.53 0.50 -0.50 0.01 -0.27 0.27 -0.62
1866 || orf19.1179 || || || Protein of unknown function; induced in high iron; possibly subject to Kex2 processing; Hap43-repressed || 1 0.64 0.68 -0.36 -0.54 -0.12 -0.48 1.32 1.11 0.32 0.09 0.85 0.00 -0.05 -0.20 -0.04 -0.77
1867 || orf19.1179 || || || Protein of unknown function; induced in high iron; possibly subject to Kex2 processing; Hap43-repressed || 1 0.76 0.65 -0.29 -0.22 -0.21 -0.56 1.42 1.33 0.28 0.01 0.92 -0.24 -0.01 -0.72 -0.12 -0.65
1868 || orf19.7673 || || || Ortholog(s) have mRNA binding activity, role in mRNA splicing, via spliceosome and U1 snRNP, U2-type prespliceosome, U4/U6 x U5 tri-snRNP complex, U5 snRNP, commitment complex, cytosol localization || 1 0.34 0.38 -0.29 -0.19 -0.08 -0.16 0.58 0.80 -0.32 0.04 0.50 -0.18 0.17 -0.56 0.07 -0.27
1869 || orf19.4205.1 || || || Ortholog(s) have role in mRNA splicing, via spliceosome and U1 snRNP, U2 snRNP, U2-type prespliceosome, U4/U6 x U5 tri-snRNP complex, U5 snRNP, cytosol localization || 1 0.40 0.30 -0.27 -0.16 -0.04 -0.32 0.58 0.90 -0.41 0.22 0.72 -0.48 -0.12 -0.10 -0.25 -0.58
1870 || orf19.2622 || YPT31 || || Protein required for resistance to toxic ergosterol analog || 1 0.22 0.36 -0.41 -0.21 -0.38 -0.95 0.38 0.67 -0.36 0.40 0.52 -0.38 0.21 -0.22 0.18 -0.32
1871 || orf19.6452 || RBP1 || || Peptidyl-prolyl cis-trans isomerase; rapamycin-binding protein; homozygous null mutation confers rapamycin resistance; regulated by Gcn4p; macrophage-induced protein; repressed in response to 3-AT; functional homolog of S. cerevisiae Rbp1p || 1 0.39 0.42 -0.10 -0.20 -0.52 -0.78 0.70 0.79 -0.10 0.02 0.69 -0.17 0.10 0.23 0.19 -0.51
1872 || orf19.4009 || CNB1 || || Regulatory subunit of calcineurin B (Ca[2+]-calmodulin-regulated S/T protein phosphatase); required for wild-type resistance to fluconazole or to SDS; micafungin is fungicidal to null mutant || 1 0.49 0.52 -0.13 -0.03 -0.45 -0.75 0.35 0.47 -0.46 0.03 0.30 -0.34 -0.03 0.15 -0.03 -0.10
1873 || orf19.6787 || || || Ortholog(s) have role in ER to Golgi vesicle-mediated transport, ascospore formation, axial cellular bud site selection and ER to Golgi transport vesicle, endoplasmic reticulum membrane localization || 1 0.44 0.20 0.12 0.51 -1.02 -0.81 0.33 1.26 -0.04 0.34 0.57 0.22 -0.21 0.51 -0.22 -0.29
1874 || orf19.6318 || || || Ortholog(s) have endoplasmic reticulum, mitochondrion localization || 1 0.57 0.49 0.40 0.81 -1.68 -1.32 1.16 1.33 0.01 -0.11 0.06 -0.30 0.43 0.05 -0.79 -0.46
1875 || orf19.2756 || || || Ortholog(s) have HDEL sequence binding activity, role in ER to Golgi vesicle-mediated transport, protein retention in ER lumen and Golgi apparatus, integral to endoplasmic reticulum membrane localization || 1 0.57 0.15 0.41 0.67 -0.77 -1.04 0.68 0.91 0.67 0.49 0.13 0.16 0.15 -0.05 -0.39 -0.43
1876 || orf19.6813 || || || Protein of unknown function; Hap43-induced gene || 1 0.80 -0.10 0.14 0.65 -0.86 -0.48 0.54 0.53 0.50 0.30 0.26 0.12 0.30 0.25 -0.29 -0.05
1877 || orf19.6971 || DIE2 || || Ortholog(s) have dolichyl-phosphate-glucose-glycolipid alpha-glucosyltransferase activity, role in protein N-linked glycosylation and endoplasmic reticulum membrane localization || 1 1.14 -0.05 0.30 0.26 -0.52 -0.77 0.72 0.61 0.22 0.14 0.23 0.25 0.17 0.47 -0.28 0.20
1878 || orf19.1340 || || || Putative aldose reductase; protein level decreases in stationary phase cultures; Spider biofilm repressed || 1 0.81 0.47 0.03 0.67 -0.96 -1.36 1.15 1.10 0.61 -0.08 0.81 0.18 0.21 0.51 -0.72 0.87
1879 || orf19.7238 || NPL3 || || Putative RNA-binding protein; required for normal flow model biofilm growth; nuclear export is facilitated by Hmt1p; transcript upregulated in RHE model of oralcandidiasis; Spider biofilm repressed || 1 0.10 0.14 -0.29 -0.02 -0.55 -1.28 0.69 0.92 -0.23 0.26 0.25 -0.44 0.16 -0.10 -1.13 -0.17
1880 || orf19.5419 || ATP5 || || Putative F0-ATP synthase FO subunit B; caspofungin repressed; protein level decreased in stationary phase yeast cultures; Spider biofilm repressed || 1 0.45 0.35 -0.28 -0.13 -0.76 -0.82 0.70 0.60 0.06 0.02 -0.22 -0.55 0.48 -0.04 -0.87 -0.18
1881 || orf19.5660.1 || || || Ortholog(s) have proton-transporting ATPase activity, rotational mechanism, structural molecule activity and role in ATP synthesis coupled proton transport, cristae formation, protein complex oligomerization || 1 0.51 0.40 -0.51 -0.21 -1.21 -1.29 1.11 1.12 0.03 0.34 0.08 -0.73 0.54 0.25 -0.52 -0.46
1882 || orf19.5660.1 || || || Ortholog(s) have proton-transporting ATPase activity, rotational mechanism, structural molecule activity and role in ATP synthesis coupled proton transport, cristae formation, protein complex oligomerization || 1 0.55 0.51 -0.63 -0.27 -1.24 -1.22 1.06 1.16 0.08 0.38 0.15 -0.56 0.55 0.21 -0.50 -0.80
1883 || orf19.2418 || || || Ortholog of C. dubliniensis CD36 : Cd36_28190, C. parapsilosis CDC317 : CPAR2_802530, Candida tenuis NRRL Y-1498 : CANTEDRAFT_109615 and Debaryomyces hansenii CBS767 : DEHA2A12650g || 1 -0.02 -0.01 -0.17 -0.08 -0.36 -0.29 0.37 0.71 0.34 0.26 0.25 -0.08 -0.25 0.18 -0.40 -0.55
1884 || orf19.913.2 || || || Ortholog of subunit 6 of the ubiquinol cytochrome-c reductase complex, a component of the mitochondrial inner membrane electron transport chain; Hap43-repressed gene || 1 0.50 0.36 -0.18 0.13 -0.90 -0.52 1.40 1.31 0.85 0.66 -0.05 -0.22 0.31 -0.07 -0.49 -0.57
1885 || orf19.913.2 || || || Ortholog of subunit 6 of the ubiquinol cytochrome-c reductase complex, a component of the mitochondrial inner membrane electron transport chain; Hap43-repressed gene || 1 0.24 0.28 -0.41 -0.12 -1.10 -0.79 1.37 1.36 0.68 0.56 -0.14 -0.38 0.03 -0.12 -0.65 -0.34
1886 || orf19.913.2 || || || Ortholog of subunit 6 of the ubiquinol cytochrome-c reductase complex, a component of the mitochondrial inner membrane electron transport chain; Hap43-repressed gene || 1 0.40 0.32 -0.32 -0.26 -1.01 -0.80 1.12 1.04 0.58 0.60 -0.32 -0.46 0.17 -0.19 -0.94 -0.65
1887 || orf19.913.2 || || || Ortholog of subunit 6 of the ubiquinol cytochrome-c reductase complex, a component of the mitochondrial inner membrane electron transport chain; Hap43-repressed gene || 1 0.25 0.11 -0.73 -0.49 -1.12 -0.90 1.09 1.14 0.57 0.51 -0.27 -0.38 -0.19 0.01 -0.89 -0.44
1888 || orf19.3527 || CYT1 || || Cytochrome c1; induced in high iron; alkaline repressed; possibly an essential gene, disruptants not obtained by UAU1 method; Hap43-repressed; Spider biofilm repressed || 1 0.21 0.12 -0.40 -0.35 -0.60 -0.92 0.80 0.85 0.56 0.42 0.18 -0.22 -0.44 -0.02 -0.20 -0.69
1889 || orf19.4316 || || || Trimethyllysine dioxygenase, the first enzyme in the carnitine biosynthesis pathway; hypha-induced expression, regulated by Cyr1, Ras1, Efg1; rat catheter biofilm repressed || 1 0.08 0.15 -0.33 -0.20 -0.25 -0.67 0.72 1.21 0.54 0.87 -0.26 -0.17 -0.48 0.31 -0.58 -0.61
1890 || orf19.4016 || || || Putative ubiquinol-cytochrome-c reductase; amphotericin B induced; repressed by nitric oxide; protein level decreases in stationary phase cultures; Hap43-repressed; Spider biofilm repressed || 1 0.14 0.10 -0.20 -0.15 -0.78 -0.70 0.87 0.88 0.64 0.74 -0.09 -0.02 -0.20 0.44 -0.27 -0.31
1891 || orf19.1682 || || || Membrane protein; Hap43p-repressed gene; repressed by nitric oxide || 1 0.62 0.37 -0.18 -0.20 -0.56 -0.70 0.90 1.10 0.62 0.73 0.21 -0.20 -0.22 0.06 -0.42 -0.51
1892 || orf19.1549 || || || Plasma membrane-associated protein identified in detergent-resistant membrane fraction (possible lipid raft component); repressed by nitric oxide; predicted transmembrane helix || 1 0.40 0.38 -0.42 -0.20 -0.76 -0.60 0.75 0.99 0.41 0.98 0.10 -0.18 -0.48 0.23 -0.23 -0.37
1893 || orf19.1549 || || || Plasma membrane-associated protein identified in detergent-resistant membrane fraction (possible lipid raft component); repressed by nitric oxide; predicted transmembrane helix || 1 0.61 0.55 -0.21 -0.07 -0.43 -0.51 0.88 1.14 0.43 0.98 0.39 0.06 -0.47 0.36 -0.08 -0.28
1894 || orf19.2418 || || || Ortholog of C. dubliniensis CD36 : Cd36_28190, C. parapsilosis CDC317 : CPAR2_802530, Candida tenuis NRRL Y-1498 : CANTEDRAFT_109615 and Debaryomyces hansenii CBS767 : DEHA2A12650g || 1 0.19 0.08 -0.37 -0.64 -0.36 -0.54 0.62 0.86 0.36 0.47 0.37 0.19 -0.10 0.78 0.30 -0.21
1895 || orf19.3757 || ATP20 || || Putative mitochondrial ATP synthase; shows colony morphology-related gene regulation by Ssn6p; flucytosine induced; caspofungin repressed; macrophage/pseudohyphal-induced || 1 0.30 0.21 -0.37 -0.12 -0.96 -1.59 0.99 1.46 0.27 0.55 0.34 -0.18 0.19 0.65 -0.30 -0.71
1896 || orf19.6062.3 || || || Mitochondrial protein; component of the mitochondrial inner membrane organizing system ; role in maintenance of crista junctions and inner membrane architecture; Spider biofilm repressed || 1 0.15 0.31 -0.32 0.20 -0.50 -0.81 0.67 1.00 0.39 0.68 0.26 -0.26 0.36 0.50 -0.13 -0.19
1897 || orf19.1055 || CDC3 || || Septin; essential for viability; functional homolog of S. cerevisiae Cdc3p; down-regulation associated with azole resistance; macrophage/pseudohyphal-repressed; virulence-group-correlated expression; gene has intron || 1 0.34 0.38 -0.45 -0.40 -0.52 -1.07 0.76 0.86 0.47 0.81 0.48 -0.27 0.35 0.66 -0.43 0.00
1898 || orf19.415 || || || Putative protein of unknown function; Hap43p-repressed gene || 1 0.16 0.15 0.04 -0.31 -0.48 -0.59 0.45 0.79 0.49 0.46 0.17 -0.26 0.24 0.57 -0.53 0.06
1899 || orf19.2862 || RIB1 || || Putative GTP cyclohydrolase II; enzyme of riboflavin biosynthesis; fungal-specific (no human or murine homolog); regulated by Sef1p-, Sfu1p-, and Hap43p || 1 0.20 0.47 -0.31 -0.46 -0.29 -0.65 0.53 0.89 0.24 0.26 0.02 -0.33 0.23 0.93 -0.27 -0.36
1900 || orf19.3757 || ATP20 || || Putative mitochondrial ATP synthase; shows colony morphology-related gene regulation by Ssn6p; flucytosine induced; caspofungin repressed; macrophage/pseudohyphal-induced || 1 0.24 0.32 -0.30 -0.28 0.14 -1.10 0.73 1.04 0.47 0.55 0.14 -0.50 0.52 0.72 -0.49 -0.45
1901 || orf19.3108 || || || Putative DNA repair methyltransferase; induced by nitric oxide independent of Yhb1; Spider biofilm induced || 1 0.35 0.17 0.03 0.21 0.01 -0.45 0.54 1.06 0.56 0.36 0.06 0.00 0.21 0.81 -0.08 -0.16
1902 || orf19.913.2 || || || Ortholog of subunit 6 of the ubiquinol cytochrome-c reductase complex, a component of the mitochondrial inner membrane electron transport chain; Hap43-repressed gene || 1 0.54 0.49 0.01 0.17 -0.75 -0.33 1.53 1.52 1.06 0.88 0.18 0.27 0.29 0.50 -0.42 -0.12
1903 || orf19.1682 || || || Membrane protein; Hap43p-repressed gene; repressed by nitric oxide || 1 0.48 0.62 0.11 0.04 -0.04 -0.50 0.95 1.34 0.89 0.95 0.40 0.22 0.23 0.40 0.03 -0.50
1904 || orf19.319 || || || Ortholog of S. cerevisiae : YDR286C, C. glabrata CBS138 : CAGL0H01111g, C. dubliniensis CD36 : Cd36_83160, C. parapsilosis CDC317 : CPAR2_101820 and Candida tenuis NRRL Y-1498 : CANTEDRAFT_113333 || 1 0.31 0.50 0.06 -0.54 0.01 -0.51 1.10 1.66 1.09 0.70 1.23 0.48 1.16 1.21 0.35 -0.33
1905 || orf19.319 || || || Ortholog of S. cerevisiae : YDR286C, C. glabrata CBS138 : CAGL0H01111g, C. dubliniensis CD36 : Cd36_83160, C. parapsilosis CDC317 : CPAR2_101820 and Candida tenuis NRRL Y-1498 : CANTEDRAFT_113333 || 1 0.07 0.10 -0.38 -0.80 -0.43 -1.05 1.19 1.51 0.70 0.58 0.88 0.15 0.78 0.88 0.00 -0.39
1906 || orf19.6062.3 || || || Mitochondrial protein; component of the mitochondrial inner membrane organizing system ; role in maintenance of crista junctions and inner membrane architecture; Spider biofilm repressed || 1 0.30 0.21 -0.08 -0.17 -0.25 -0.60 0.94 1.31 0.48 0.92 0.44 -0.00 0.31 0.65 0.02 -0.08
1907 || orf19.415 || || || Putative protein of unknown function; Hap43p-repressed gene || 1 0.36 0.41 -0.14 -0.23 -0.47 -0.53 0.87 1.08 0.64 0.57 0.42 -0.02 0.34 0.94 0.01 0.33
1908 || orf19.291 || || || Ortholog(s) have role in cellular response to DNA damage stimulus, protein sumoylation, response to UV-B, response to UV-C and nuclear envelope localization || 1 0.27 0.40 -0.47 -0.02 0.06 -0.45 0.75 0.70 0.63 0.40 0.28 0.03 0.34 0.48 0.02 0.10
1909 || orf19.1055 || CDC3 || || Septin; essential for viability; functional homolog of S. cerevisiae Cdc3p; down-regulation associated with azole resistance; macrophage/pseudohyphal-repressed; virulence-group-correlated expression; gene has intron || 1 -0.02 0.15 -0.11 0.01 -0.26 -0.66 0.40 0.49 0.47 0.85 0.13 0.21 0.23 0.67 -0.28 -0.06
1910 || orf19.5074 || UBA2 || || Ortholog(s) have SUMO activating enzyme activity, role in protein sumoylation and SUMO activating enzyme complex localization || 1 0.39 0.36 -0.03 -0.33 -0.08 -0.50 0.44 0.50 0.58 0.40 -0.09 0.11 0.58 0.45 -0.05 -0.30
1911 || orf19.1440 || || || Ortholog of C. dubliniensis CD36 : Cd36_43090, C. parapsilosis CDC317 : CPAR2_403340, Candida tenuis NRRL Y-1498 : CANTEDRAFT_94387 and Debaryomyces hansenii CBS767 : DEHA2G17622g || 1 0.52 0.68 -0.06 -0.19 -0.35 -0.41 1.42 0.56 0.48 0.36 -0.40 -0.18 0.67 0.69 0.16 -0.57
1912 || orf19.7678 || ATP16 || || Subunit of the mitochondrial F1F0 ATP synthase; sumoylation target; protein newly produced during adaptation to the serum; Spider biofilm repressed || 1 0.39 0.47 -0.37 -0.43 -0.30 -0.29 1.09 0.84 0.33 0.34 0.12 -0.23 0.52 0.38 0.01 -0.21
1913 || orf19.5662 || PEP7 || || Vesicle transport protein; acts in endosomal transport; roles in metal ion resistance, virulence, adhesion, hyphal growth, chlamydospore formation; similar to S. cerevisiae Pep7p || 1 0.34 0.63 0.36 0.17 -0.10 -0.24 0.68 0.65 0.98 0.16 -0.04 -0.27 0.31 0.04 0.41 0.22
1914 || orf19.5097 || CAT8 || || Zn(II)2Cys6 transcription factor; similar to S. cerevisiae Cat8 but mutant phenotype suggests different target genes; mutant displays increased filamentous/invasive growth; flucytosine repressed; rat catheter biofilm induced || 1 0.87 1.27 0.16 0.49 -0.67 -0.75 1.25 1.45 1.32 -0.12 -0.19 -0.14 1.05 -0.08 0.31 -0.18
1915 || orf19.1467 || COX13 || || Cytochrome c oxidase; flucytosine induced; repressed by nitric oxide || 1 0.54 0.60 0.49 0.18 -0.33 -0.20 0.65 0.61 0.50 -0.04 -0.19 -0.51 0.27 0.32 -0.23 -0.39
1916 || orf19.7131 || || || Butyrobetaine dioxygenase, the fourth enzyme of the carnitine biosynthesis pathway || 1 0.73 0.74 0.30 0.52 -0.56 -0.30 1.13 1.09 0.79 0.43 -0.40 -0.69 -0.05 0.02 -0.10 -0.85
1917 || orf19.7131 || || || Butyrobetaine dioxygenase, the fourth enzyme of the carnitine biosynthesis pathway || 1 0.76 0.79 0.35 0.23 -0.55 -0.47 1.24 1.02 0.94 0.55 -0.37 -0.52 -0.14 0.49 0.06 -0.77
1918 || orf19.1414 || || || Protein of unknown function; transcript is upregulated in an RHE model of oral candidiasis; Hap43-repressed || 1 0.37 0.36 0.24 0.50 -0.10 -0.67 0.73 0.69 0.53 0.39 -0.11 -0.42 0.16 0.15 -0.61 -0.47
1919 || orf19.4759 || COX5 || || Cytochrome oxidase subunit V; putative upstream CCAAT box regulatory element; macrophage/pseudohyphal-induced; repressed by nitric oxide; intron in 5'-UTR; Hap43p-dependent repression in low iron medium || 1 0.91 0.82 0.35 0.24 0.01 -0.31 0.99 1.18 0.67 0.55 -0.18 -0.47 0.30 0.12 -0.57 -0.61
1920 || orf19.2439.1 || || || Ortholog(s) have ubiquinol-cytochrome-c reductase activity, role in aerobic respiration, mitochondrial electron transport, ubiquinol to cytochrome c and mitochondrial respiratory chain complex III localization || 1 0.98 1.07 0.64 0.49 -0.42 -0.23 1.55 1.41 0.74 0.34 0.17 -0.08 0.70 -0.31 -0.41 -0.32
1921 || orf19.2439.1 || || || Ortholog(s) have ubiquinol-cytochrome-c reductase activity, role in aerobic respiration, mitochondrial electron transport, ubiquinol to cytochrome c and mitochondrial respiratory chain complex III localization || 1 0.85 0.86 0.35 0.31 -0.54 -0.34 1.41 1.22 0.56 0.20 0.04 -0.06 0.38 -0.07 -0.46 -0.40
1922 || orf19.2439.1 || || || Ortholog(s) have ubiquinol-cytochrome-c reductase activity, role in aerobic respiration, mitochondrial electron transport, ubiquinol to cytochrome c and mitochondrial respiratory chain complex III localization || 1 0.94 0.88 0.52 0.37 -0.59 -0.23 1.54 1.37 0.72 0.33 0.30 -0.25 0.46 -0.01 -0.58 -0.56
1923 || orf19.2439.1 || || || Ortholog(s) have ubiquinol-cytochrome-c reductase activity, role in aerobic respiration, mitochondrial electron transport, ubiquinol to cytochrome c and mitochondrial respiratory chain complex III localization || 1 0.74 0.65 0.19 0.14 -0.87 -0.51 1.35 1.11 0.42 0.05 0.14 -0.36 0.16 0.07 -0.40 -0.36
1924 || orf19.2439.1 || || || Ortholog(s) have ubiquinol-cytochrome-c reductase activity, role in aerobic respiration, mitochondrial electron transport, ubiquinol to cytochrome c and mitochondrial respiratory chain complex III localization || 1 0.70 0.75 0.28 0.03 -0.75 -0.52 1.34 1.15 0.45 0.18 0.12 -0.58 0.27 -0.24 -0.50 -0.78
1925 || orf19.5181 || NIK1 || || Histidine kinase involved in a two-component signaling pathway that regulates cell wall biosynthesis; required for wild-type virulence in mouse systemic infection but not for wild-type growth or drug sensitivity/resistance; 9 HAMP domains || 1 0.62 0.61 0.26 0.30 -0.31 -0.38 0.56 0.67 0.40 0.20 0.01 -0.41 0.64 0.12 -0.28 -0.54
1926 || orf19.5181 || NIK1 || || Histidine kinase involved in a two-component signaling pathway that regulates cell wall biosynthesis; required for wild-type virulence in mouse systemic infection but not for wild-type growth or drug sensitivity/resistance; 9 HAMP domains || 1 0.56 0.72 0.16 0.12 -0.14 -0.51 0.56 0.79 0.40 0.03 -0.01 -0.24 0.74 0.52 -0.17 -0.66
1927 || orf19.5491.1 || ATP14 || || Putative mitochondrial F1F0 ATP synthase subunit; macrophage/pseudohyphal-induced || 1 1.09 1.08 0.44 0.56 -0.39 -0.62 1.42 1.41 0.74 0.40 0.27 -0.35 1.25 0.90 -0.37 -0.24
1928 || orf19.5231.2 || ATP19 || || Subunit k of the mitochondrial F1F0 ATP synthas; a large enzyme complex required for ATP synthesis; Spider biofilm repressed || 1 1.49 1.67 0.17 0.23 -1.26 -1.20 1.87 2.05 0.72 0.99 0.58 -0.25 1.08 0.93 -0.64 -0.12
1929 || orf19.2785 || ATP7 || || Putative subunit of the F1F0-ATPase complex; colony morphology-related gene regulation by Ssn6; farnesol, macrophage-downregulated protein abundance; protein present in exponential and stationary yeast growth phases; Hap43-induced || 1 0.61 0.69 -0.01 0.14 -0.46 -0.91 1.06 1.17 0.38 0.33 0.05 -0.50 0.63 0.85 0.01 -0.22
1930 || orf19.5491.1 || ATP14 || || Putative mitochondrial F1F0 ATP synthase subunit; macrophage/pseudohyphal-induced || 1 0.62 0.95 0.11 0.21 -0.61 -0.87 1.28 1.34 0.34 0.27 0.23 -0.67 1.06 0.64 -0.51 -0.82
1931 || orf19.7509.1 || ATP17 || || Mitochondrial ATPase complex subunit; downregulated by Efg1p; flucytosine induced; caspofungin repressed || 1 0.92 0.98 -0.26 0.18 -0.79 -1.33 1.69 1.65 0.50 0.22 0.29 -0.36 1.29 0.43 -0.40 -0.88
1932 || orf19.7509.1 || ATP17 || || Mitochondrial ATPase complex subunit; downregulated by Efg1p; flucytosine induced; caspofungin repressed || 1 0.92 0.82 -0.01 0.40 -0.73 -1.00 1.70 1.71 0.49 0.16 0.65 -0.67 1.15 0.21 -0.22 -0.69
1933 || orf19.5231.2 || ATP19 || || Subunit k of the mitochondrial F1F0 ATP synthas; a large enzyme complex required for ATP synthesis; Spider biofilm repressed || 1 0.94 1.04 0.39 0.65 -0.67 -1.26 1.20 1.47 0.53 0.69 0.54 -0.61 0.61 0.30 -0.71 -0.54
1934 || orf19.6414 || || || Ortholog of C. dubliniensis CD36 : Cd36_34040, C. parapsilosis CDC317 : CPAR2_205850, Candida tenuis NRRL Y-1498 : CANTEDRAFT_132607 and Debaryomyces hansenii CBS767 : DEHA2A11638g || 1 0.77 0.87 0.59 0.73 -0.66 -1.31 0.83 0.87 0.70 0.72 0.39 -0.49 0.55 0.31 -0.56 -0.34
1935 || orf19.1848.1 || || || Ortholog of S. cerevisiae : KSH1, C. dubliniensis CD36 : Cd36_32390, C. parapsilosis CDC317 : CPAR2_203260, Candida tenuis NRRL Y-1498 : CANTEDRAFT_116778 and Debaryomyces hansenii CBS767 : DEHA2A10604g || 1 0.67 0.66 0.23 0.09 -0.41 -0.68 0.57 0.81 -0.08 0.22 0.04 -0.56 0.43 0.09 -0.21 -0.72
1936 || orf19.5142 || DFR1 || || Trimethoprim resistant dihydrofolate reductase (DHFR), reduces 7,8-dihydrofolate to 5,4,7,8-tetrahydrofolate; binds NADPH; target of drugs that selectively inhibit the fungal enzyme rather than the human enzyme || 1 0.62 0.81 0.26 0.55 -0.03 -0.38 0.27 0.92 0.15 0.60 -0.22 -0.55 0.15 0.15 -0.20 -0.42
1937 || orf19.6561 || LAT1 || || Putative dihydrolipoamide acetyltransferase component (E2) of pyruvate dehydrogenase complex; sumoylation target; Spider biofilm repressed || 1 1.31 1.37 0.62 0.51 0.32 -0.14 0.88 1.22 0.19 0.39 0.11 -0.56 0.70 0.31 -0.83 -0.15
1938 || orf19.1057 || || || Ortholog of C. dubliniensis CD36 : Cd36_03980, C. parapsilosis CDC317 : CPAR2_107050, Candida tenuis NRRL Y-1498 : CANTEDRAFT_113999 and Debaryomyces hansenii CBS767 : DEHA2D12518g || 1 0.23 0.34 0.41 -0.19 -0.01 0.01 0.41 0.53 0.22 0.12 0.10 0.09 0.24 0.32 -0.17 -0.06
1939 || orf19.5266 || || || Planktonic growth-induced gene || 1 1.11 1.55 0.21 -0.52 -0.26 1.12 0.28 0.40 0.68 -0.24 0.22 0.66 0.36
1940 || orf19.1617 || || || Protein similar to S. cerevisiae Ydr282cp; transposon mutation affects filamentous growth; Hap43p-repressed gene || 1 0.88 0.76 0.17 0.02 0.06 0.07 0.64 0.35 0.43 0.09 -0.13 -0.07 0.50 0.60 0.18 0.53
1941 || orf19.1910 || || || Predicted NADH-dependent flavin oxidoreductase; Hap43-repressed gene || 1 0.69 0.84 0.14 0.20 0.25 0.10 0.57 0.53 0.14 0.14 -0.33 -0.46 0.86 0.97 -0.07 0.46
1942 || orf19.6025 || || || Ortholog(s) have N-acetylglucosaminyldiphosphodolichol N-acetylglucosaminyltransferase activity and role in dolichol-linked oligosaccharide biosynthetic process || 1 0.49 0.60 -0.85 -0.34 0.02 -0.66 0.34 0.70 0.53 0.22 0.38 -0.43 0.77 0.37 0.15 0.36
1943 || orf19.4646 || UEC1 || || Protein required for damage to oral epithelial cells and for normal hyphal growth and stress resistance; transcription induced on contact with vascular endothelial cells; not highly conserved || 1 0.51 0.68 0.34 -0.26 0.53 -0.98 1.20 1.10 0.77 0.47 0.63 -0.64 1.42 0.47 0.26 -0.17
1944 || orf19.4646 || UEC1 || || Protein required for damage to oral epithelial cells and for normal hyphal growth and stress resistance; transcription induced on contact with vascular endothelial cells; not highly conserved || 1 0.61 0.74 0.01 -0.38 0.68 -0.81 1.08 1.18 0.63 0.54 0.88 -0.28 1.99 0.73 0.18 0.15
1945 || orf19.4646 || UEC1 || || Protein required for damage to oral epithelial cells and for normal hyphal growth and stress resistance; transcription induced on contact with vascular endothelial cells; not highly conserved || 1 0.63 0.77 -0.06 -0.41 0.74 -1.02 0.86 0.72 1.05 0.52 0.69 -0.21 1.84 0.47 -0.06 0.03
1946 || orf19.4646 || UEC1 || || Protein required for damage to oral epithelial cells and for normal hyphal growth and stress resistance; transcription induced on contact with vascular endothelial cells; not highly conserved || 1 0.59 0.72 -0.02 -0.30 0.74 -0.76 1.03 1.17 0.94 0.44 0.71 -0.35 1.63 0.56 -0.03 -0.70
1947 || orf19.4646 || UEC1 || || Protein required for damage to oral epithelial cells and for normal hyphal growth and stress resistance; transcription induced on contact with vascular endothelial cells; not highly conserved || 1 0.64 0.95 -0.15 -0.42 0.86 -0.71 1.12 1.28 1.00 0.47 0.51 -0.43 2.05 0.78 0.20 -0.75
1948 || orf19.660 || || || Protein of unknown function; mRNA binds She3 || 1 0.24 0.20 0.03 -0.25 -0.03 -0.68 0.73 0.67 0.12 0.62 0.29 0.35 1.13 1.14 -0.16 -0.55
1949 || orf19.5702 || || || Ortholog(s) have cell division site, spindle localization || 1 0.25 0.24 -0.45 -0.32 -0.22 -0.69 0.36 0.43 0.28 0.15 0.06 0.05 0.40 0.51 -0.05 -0.21
1950 || orf19.6783 || || || Putative geranylgeranyltransferase regulatory component || 1 0.12 0.28 -0.34 -0.49 -0.28 -0.70 0.38 0.27 0.23 0.06 0.09 0.03 0.64 0.63 0.58 -0.42
1951 || orf19.135 || EXO84 || || Predicted subunit of the exocyst complex, involved in exocytosis; localizes to a crescent on the surface of the hyphal tip || 1 0.21 0.29 -0.26 -0.47 -0.22 -0.73 0.39 0.35 0.12 -0.20 0.67 0.01 0.57 0.58 0.44 0.09
1952 || orf19.2369.1 || ATX1 || || Putative cytosolic copper metallochaperone; flucytosine induced; Ssr1-repressed; rat catheter biofilm induced || 1 0.57 0.67 -1.14 -1.28 -0.39 -1.54 0.60 1.37 0.23 -0.26 1.00 -0.46 2.24 1.95 0.70 -0.21
1953 || orf19.2369.1 || ATX1 || || Putative cytosolic copper metallochaperone; flucytosine induced; Ssr1-repressed; rat catheter biofilm induced || 1 0.70 1.18 -0.62 -0.46 -0.18 -1.19 0.74 1.85 0.94 0.18 0.90 -0.27 2.60 2.38 0.49 -0.58
1954 || orf19.3254 || || || Ortholog of C. dubliniensis CD36 : Cd36_26020, Candida tropicalis MYA-3404 : CTRG_00984 and Candida albicans WO-1 : CAWG_01455 || 1 0.19 -0.03 -0.92 -0.68 0.15 -0.57 0.35 0.36 -0.16 0.30 0.42 0.21 1.24 0.69 0.46 -0.19
1955 || orf19.6742 || || || Ortholog(s) have CTD phosphatase activity || 1 0.13 -0.09 0.11 0.03 -0.05 -0.11 -0.03 0.25 -0.01 0.34 0.12 -0.00 0.38 0.57 0.22 0.10
1956 || orf19.7303 || || || Ortholog of C. dubliniensis CD36 : Cd36_34495, Candida tropicalis MYA-3404 : CTRG_05947 and Candida albicans WO-1 : CAWG_02181 || 1 0.68 0.45 0.35 -0.12 0.35 -0.68 0.18 0.58 0.30 0.58 -0.02 -0.19 0.89 1.03 0.32 0.24
1957 || orf19.1747 || KIP2 || || Putative kinesin-related motor protein involved in mitotic spindle positioning; repressed by alpha pheromone in SpiderM medium; periodic mRNA expression, peak at cell-cycle G2/M phase || 1 0.27 0.37 0.29 0.14 -0.26 -0.81 0.77 0.60 0.24 0.70 0.16 -0.20 0.86 0.87 -0.47 0.41
1958 || orf19.3100 || || || Protein with t-SNARE domains and a microtubule associated domain; Hap43-induced gene; repressed by alpha pheromone in SpiderM medium || 1 0.52 0.84 0.80 0.91 -0.60 -1.22 0.58 1.48 0.14 0.79 0.77 0.19 3.63 1.92 -1.02 0.51
1959 || orf19.3100 || || || Protein with t-SNARE domains and a microtubule associated domain; Hap43-induced gene; repressed by alpha pheromone in SpiderM medium || 1 0.59 0.65 0.82 0.62 0.03 -1.03 0.22 0.92 -0.14 0.66 0.88 -0.12 2.94 1.68 -0.56 -0.06
1960 || orf19.2736 || HFL2 || || HAP5-like; ortholog of S. cerevisiae Bur6, a heterodimeric NC2 transcription regulator complex subunit; flucytosine induced || 1 0.46 -0.06 0.37 0.33 -0.37 0.03 0.19 0.85 0.37 0.35 0.32 -0.21 0.67 0.48 0.13 -0.49
1961 || orf19.5001 || CUP2 || || Putative copper-binding transcription factor; required for normal resistance to copper; activates transcription of metallothionein genes; Hap43-repressed; Spider biofilm induced || 1 0.32 0.54 0.50 0.15 0.06 0.10 0.40 0.06 0.21 -0.02 -0.26 0.02 0.63 0.49 -0.03 -0.42
1962 || orf19.5110 || OPY2 || || Predicted transmembrane protein; role in cell wall biogenesis; required for Cek1 phosphorylation; Spider biofilm induced || 1 0.38 0.25 0.63 0.67 0.62 -0.22 0.95 0.37 0.41 0.46 -0.12 0.10 0.77 0.46 0.75 -0.22
1963 || orf19.5576 || || || Putative pantothenate kinase; ortholog of S. cerevisiae Cab1; transposon mutation affects filamentous growth; repressed in core stress response || 1 0.12 0.04 0.43 0.37 0.27 0.13 0.34 0.10 0.34 0.41 0.15 0.01 0.65 0.37 0.32 -0.22
1964 || orf19.3755 || || || Ortholog(s) have structural constituent of ribosome activity and mitochondrial large ribosomal subunit localization || 1 0.20 0.35 0.50 0.77 0.96 0.27 0.46 0.54 0.45 0.28 0.25 0.22 0.61 0.79 0.36 -0.44
1965 || orf19.6778 || || || Aminophospholipid translocase (flippase); maintains membrane lipid asymmetry in post-Golgi secretory vesicles; contributes to clathrin-coated vesicle formation and endocytosis; flow model biofilm repressed || 1 0.11 0.51 0.64 0.42 0.64 0.11 0.22 0.21 0.68 0.42 0.04 0.23 0.58 0.44 0.04 -0.33
1966 || orf19.4243 || || || Ortholog(s) have ubiquitin binding activity || 1 0.53 0.70 0.67 0.65 0.35 -0.31 0.53 0.17 0.78 0.80 0.28 0.65 1.06 0.54 0.35 -0.27
1967 || orf19.3436 || || || Protein with a Rho GDP-dissociation inhibitor domain; macrophage-induced gene || 1 0.29 0.36 0.32 0.58 0.08 -0.18 0.44 0.09 0.74 0.38 0.12 1.02 0.72 0.33 0.03
1968 || orf19.6309 || MSS11 || || Transcription factor; activator that binds to Flo8 via a LisH motif to cooperatively activate transcription of hypha-specific genes; required for hyphal growth || 1 0.39 0.54 0.45 0.49 -0.22 -0.42 0.32 0.25 0.65 0.45 -0.17 0.25 1.60 0.89 0.30 0.00
1969 || orf19.4349 || || || Protein of unknown function; transcript repressed by elevated CO2; Spider biofilm induced || 1 0.77 1.21 0.42 0.43 -0.72 -1.02 1.26 0.99 0.65 0.62 0.07 0.05 2.13 1.29 -0.20 0.13
1970 || orf19.6712 || || || Ortholog(s) have COPI-coated vesicle, Golgi apparatus localization || 1 0.48 0.47 0.08 0.09 0.03 -0.79 0.85 0.62 0.66 0.48 0.47 0.17 0.75 0.65 -0.05 -0.08
1971 || orf19.5702 || || || Ortholog(s) have cell division site, spindle localization || 1 0.45 0.29 0.09 0.15 0.01 -0.23 0.50 0.53 0.58 0.18 0.06 0.10 0.53 0.45 0.05 -0.03
1972 || orf19.7678 || ATP16 || || Subunit of the mitochondrial F1F0 ATP synthase; sumoylation target; protein newly produced during adaptation to the serum; Spider biofilm repressed || 1 0.60 0.59 0.05 0.25 -0.28 -0.08 1.14 0.99 0.60 0.35 0.25 0.08 0.73 0.68 0.12 0.06
1973 || orf19.5181 || NIK1 || || Histidine kinase involved in a two-component signaling pathway that regulates cell wall biosynthesis; required for wild-type virulence in mouse systemic infection but not for wild-type growth or drug sensitivity/resistance; 9 HAMP domains || 1 0.48 0.44 0.67 0.38 -0.27 -0.14 0.85 0.72 0.76 0.39 0.11 0.04 0.66 0.64 -0.40 -0.08
1974 || orf19.4264 || || || Protein of unknown function; induced during chlamydospore formation in both C. albicans and C. dubliniensis; flow model biofilm induced || 1 0.49 0.67 1.01 0.69 -0.09 -0.25 0.24 0.75 1.39 0.61 0.13 -0.29 1.13 1.02 0.10 0.09
1975 || orf19.2018.1 || || || PProtein of unknown function; gene has intron; similar to human BLOC1S2 || 1 0.40 0.60 0.29 0.49 0.22 -0.12 0.65 0.75 1.23 0.80 0.49 -0.21 1.06 1.13 0.11 -0.09
1976 || orf19.5553 || || || Ortholog(s) have methionine-R-sulfoxide reductase activity, role in cellular response to oxidative stress and cytoplasm, nucleus localization || 1 0.16 0.28 0.46 0.24 0.21 -0.21 0.48 0.65 0.65 0.37 0.11 -0.06 0.74 0.75 0.02 -0.52
1977 || orf19.4927 || BNI1 || || Formin; role in cytoskeletal organization, cell polarity; role in systemic virulence in mouse; cell-cycle regulated localization to site of polarized growth, bud neck; localizes to Spitzenkorper of hyphae, minor localization at septum || 1 0.19 0.19 0.37 0.16 -0.20 -0.67 0.70 0.62 0.82 0.31 0.02 -0.17 0.72 0.72 0.14 -0.47
1978 || orf19.3688 || || || Ortholog(s) have chromatin DNA binding activity and role in cell wall mannoprotein biosynthetic process, positive regulation of transcription from RNA polymerase II promoter, telomere maintenance || 1 0.37 0.40 0.27 0.47 0.37 -0.17 0.51 0.42 0.54 0.14 -0.01 -0.00 0.46 0.77 0.12 -0.20
1979 || orf19.3108 || || || Putative DNA repair methyltransferase; induced by nitric oxide independent of Yhb1; Spider biofilm induced || 1 0.22 0.25 0.27 0.53 0.06 -0.16 0.32 0.44 0.29 0.10 -0.18 -0.05 0.31 0.65 -0.06 -0.13
1980 || orf19.1440 || || || Ortholog of C. dubliniensis CD36 : Cd36_43090, C. parapsilosis CDC317 : CPAR2_403340, Candida tenuis NRRL Y-1498 : CANTEDRAFT_94387 and Debaryomyces hansenii CBS767 : DEHA2G17622g || 1 0.53 0.50 0.33 0.54 -0.31 -0.23 0.92 0.32 0.44 0.34 -0.16 -0.49 0.67 0.69 0.23 -0.40
1981 || orf19.1671 || UTR2 || || Putative GPI anchored cell wall glycosidase; role in adhesion, hyphal growth on Spider (not serum) medium; chitin-binding, glycosyl hydrolase domains; induced during cell wall regeneration; mRNA in yeast-form cells; Spider biofilm induced || 1 0.17 0.39 0.31 0.10 -0.50 -0.40 0.79 0.62 0.75 0.27 -0.63 -0.69 1.11 0.87 0.30 -0.31
1982 || orf19.3767 || PEP1 || || Type I transmembrane sorting receptor for multiple vacuolar hydrolases; cycles between late-Golgi and prevacuolar endosome-like compartments; rat catheter biofilm repressed || 1 0.31 0.27 0.50 0.52 -0.24 -0.48 0.42 0.39 0.45 -0.07 -0.26 0.02 0.77 0.26 -0.15 -0.23
1983 || orf19.7545 || || || Protein similarity to mutator-like element (MULE) transposase || 1 0.51 0.67 0.69 0.45 -0.08 -0.09 0.28 0.85 0.48 0.55 -0.26 -0.56 0.43 0.96 -0.21 -0.23
1984 || orf19.4570 || || || Ortholog of C. dubliniensis CD36 : Cd36_42090, Debaryomyces hansenii CBS767 : DEHA2C14872g, Pichia stipitis Pignal : PICST_74821 and Spathaspora passalidarum NRRL Y-27907 : SPAPADRAFT_58607 || 1 0.95 0.85 1.45 1.09 0.35 -0.34 1.27 1.79 0.52 0.98 -0.23 -0.60 0.91 0.79 0.68 0.33
1985 || orf19.29 || || || Ortholog of S. cerevisiae Tah11, a DNA replication licensing factor required for pre-replication complex assembly; rat catheter, flow model and Spider biofilm induced || 1 2.44 1.12 0.71 1.19 0.75 0.31 2.62 1.49 0.73 1.16 1.04 -0.33 1.82 1.38 -0.40 -0.70
1986 || orf19.4721 || || || Ortholog(s) have RNA binding activity, role in cytoplasmic translation, mRNA processing and mitochondrion localization || 1 0.74 0.57 0.30 0.09 0.39 -0.28 1.01 0.95 0.56 0.97 -0.44 -1.20 1.06 0.95 -0.17 -0.93
1987 || orf19.3851 || || || Protein of unknown function; induced by alpha pheromone in SpiderM medium || 1 0.60 0.50 0.37 0.58 0.42 0.09 1.14 0.42 0.90 0.33 -0.36 -0.73 0.65 0.34 0.16 -0.32
1988 || orf19.792 || || || Ortholog(s) have protein serine/threonine kinase activity, role in activation of bipolar cell growth, protein phosphorylation, regulation of cytokinesis, regulation of mitotic sister chromatid segregation and cytosol, nucleus localization || 1 0.88 0.91 0.84 1.29 0.52 0.61 1.00 0.10 0.88 1.00 -0.66 -0.34 1.65 0.65 -0.39 -0.70
1989 || orf19.2506 || || || Protein of unknown function; opaque-specific transcript; induced during chlamydospore formation in both C. albicans and C. dubliniensis; Hog1-repressed; Spider biofilm induced || 1 0.41 0.86 0.80 0.49 0.80 0.16 0.30 0.24 1.50 0.94 -0.34 -0.81 1.58 1.13 0.06 -0.71
1990 || orf19.7037 || YAE1 || || Ortholog(s) have role in ribosomal large subunit biogenesis, translational initiation and cytoplasm, nucleus localization || 1 0.61 0.75 0.19 0.15 0.57 0.33 0.39 0.35 0.70 0.12 -0.31 -0.45 0.57 0.50 -0.16 -0.95
1991 || orf19.7488 || || || Component of the SSU processome; predicted role in pre-18S rRNA processing; Spider biofilm induced || 1 1.51 1.59 0.78 0.71 1.01 1.19 0.93 0.90 0.13 1.24 0.06 -1.02 0.98 0.84 -0.20 -1.78
1992 || orf19.7488 || || || Component of the SSU processome; predicted role in pre-18S rRNA processing; Spider biofilm induced || 1 1.53 1.71 0.97 0.59 0.96 0.89 1.47 1.07 0.18 1.48 0.19 -1.21 1.07 1.07 -0.20 -1.80
1993 || orf19.4153 || || || Ortholog(s) have NEDD8 activating enzyme activity, role in protein neddylation and cytosol, nucleus localization || 1 0.87 0.68 0.04 0.41 0.15 -0.05 0.45 0.48 0.34 0.69 -0.11 -0.08 0.20 0.25 0.17 -0.38
1994 || orf19.4570 || || || Ortholog of C. dubliniensis CD36 : Cd36_42090, Debaryomyces hansenii CBS767 : DEHA2C14872g, Pichia stipitis Pignal : PICST_74821 and Spathaspora passalidarum NRRL Y-27907 : SPAPADRAFT_58607 || 1 1.45 1.57 0.18 1.13 0.66 0.42 0.85 0.95 0.91 1.23 0.08 0.82 0.60 0.32 -1.21
1995 || orf19.3519 || SUA72 || || Predicted transcription factor; induced during planktonic growth, whereas related SUA71 is downregulated || 1 0.38 0.99 -0.19 0.66 -0.02 -0.13 0.60 0.41 0.60 0.61 0.02 -0.06 0.35 0.22 0.27 -0.73
1996 || orf19.6400 || || || Ortholog(s) have role in inositol metabolic process and cytosol, nuclear envelope localization || 1 0.18 0.35 -0.02 0.25 -0.01 -0.12 0.35 0.09 0.08 0.08 0.19 0.00 0.55 0.15 0.18 -0.26
1997 || orf19.4282 || IFH1 || || Transcription factor; forms a heterodimer with Fhl11 that is tethered to promoters by Tbf1; positively regulates rRNA and ribosomal protein gene transcription; Spider biofilm induced || 1 0.59 0.67 -0.06 0.01 0.41 0.54 0.55 0.79 0.64 0.57 -0.04 -0.44 1.94 0.61 0.54 -0.38
1998 || orf19.4282 || IFH1 || || Transcription factor; forms a heterodimer with Fhl11 that is tethered to promoters by Tbf1; positively regulates rRNA and ribosomal protein gene transcription; Spider biofilm induced || 1 0.40 0.23 -0.03 -0.04 0.11 0.03 0.23 0.27 0.84 0.58 -0.22 -0.56 1.36 0.59 0.54 -0.91
1999 || orf19.715 || || || Protein of unknown function; Hap43-induced; rat catheter and Spider biofilm induced || 1 0.82 1.03 0.50 0.45 0.41 0.04 0.80 0.52 1.39 0.58 -0.36 0.21 2.24 1.36 1.38 -1.19
2000 || orf19.715 || || || Protein of unknown function; Hap43-induced; rat catheter and Spider biofilm induced || 1 1.24 1.35 0.14 0.24 0.45 -0.25 1.22 0.69 1.63 0.65 -0.32 0.39 2.76 1.39 2.02 -1.77
2001 || orf19.4849 || || || Protein required for localizing proteasomes to the nucleus; involved in ubiquitin-mediated protein degradation; possibly an essential gene, disruptants not obtained by UAU1 method; Spider biofilm induced || 1 0.37 0.51 -0.05 0.06 0.25 -0.15 0.71 0.36 0.41 0.64 0.21 -0.19 0.65 0.43 0.29 -0.60
2002 || orf19.1499 || CTF1 || || Putative zinc-finger transcription factor, similar to A. nidulans FarA and FarB; activates genes required for fatty acid degradation; induced by oleate; null mutant displays carbon source utilization defects and slightly reduced virulence || 1 0.35 0.44 -0.34 -0.05 0.98 -0.05 0.83 0.66 0.20 0.41 -0.30 -0.11 1.13 0.43 0.72 -0.73
2003 || orf19.723 || BCR1 || || Transcription factor; regulates a/alpha biofilm formation, matrix, cell-surface-associated genes; confers adherence, impermeability, impenetrability, fluconazole resistance; Tup1/Tec1/Mnl1-regulated; mRNA binds She3; Spider biofilm induced || 1 0.42 0.51 0.16 0.54 0.21 -0.01 0.48 -0.03 0.60 0.69 -0.50 -0.21 0.88 -0.03 0.83 -0.58
2004 || orf19.6783 || || || Putative geranylgeranyltransferase regulatory component || 1 0.03 0.11 0.19 0.22 -0.40 -0.29 0.29 -0.04 0.31 0.08 -0.12 0.16 0.70 0.35 0.25 -0.83
2005 || orf19.7303 || || || Ortholog of C. dubliniensis CD36 : Cd36_34495, Candida tropicalis MYA-3404 : CTRG_05947 and Candida albicans WO-1 : CAWG_02181 || 1 -0.01 0.62 -0.72 1.16 -1.23 -1.31 1.40 0.23 1.60 1.21 -0.13 -0.45 2.12 1.20 -2.41
2006 || orf19.103 || KAR5 || || Ortholog of S. cerevisiae Kar5; involved in nuclear membrane fusion during karyogamy; induced by alpha factor || 1 0.10 0.46 -0.01 1.27 -0.19 -0.67 0.25 0.49 0.66 0.46 0.14 -0.54 0.60 1.46 -0.05 -2.51
2007 || orf19.4783 || || || Protein of unknown function; induced during chlamydospore formation in both C. albicans and C. dubliniensis || 1 -0.25 -0.04 -0.10 -0.19 -0.06 -1.25 -0.35 -0.07 0.67 0.35 -0.12 -0.61 0.46 1.30 -0.33 -0.88
2008 || orf19.4783 || || || Protein of unknown function; induced during chlamydospore formation in both C. albicans and C. dubliniensis || 1 -0.12 0.38 0.22 0.29 -0.44 -1.35 -0.26 0.46 0.59 0.00 -0.02 -1.30 0.24 1.09 -0.56 -0.89
2009 || orf19.4136 || YBL053 || || Ortholog(s) have protein heterodimerization activity || 1 0.22 0.46 -0.13 0.32 -0.26 -1.80 0.14 1.25 0.03 1.24 0.46 -1.28 0.14 0.82 -0.74 -0.96
2010 || orf19.3940 || || || Ortholog of C. dubliniensis CD36 : Cd36_54170, C. parapsilosis CDC317 : CPAR2_100960, Candida tenuis NRRL Y-1498 : CANTEDRAFT_96367 and Debaryomyces hansenii CBS767 : DEHA2G24618g || 1 0.36 0.21 -0.23 0.00 -0.15 -1.53 0.59 1.03 0.35 0.15 -0.17 -1.50 0.19 0.98 -0.57 -1.12
2011 || orf19.1793 || || || Ortholog(s) have phosphatidylinositol binding activity, role in cellular response to nitrogen starvation, piecemeal microautophagy of nucleus and Golgi apparatus, endosome, extrinsic to membrane, fungal-type vacuole localization || 1 0.31 0.27 -0.28 0.07 0.16 -0.71 0.38 0.35 -0.09 0.22 0.23 -0.78 0.28 0.29 -0.47 -0.57
2012 || orf19.4316 || || || Trimethyllysine dioxygenase, the first enzyme in the carnitine biosynthesis pathway; hypha-induced expression, regulated by Cyr1, Ras1, Efg1; rat catheter biofilm repressed || 1 0.39 0.51 0.06 -0.04 0.33 -0.76 0.47 0.68 0.61 0.55 -0.04 -0.67 0.32 0.08 -0.28 -0.91
2013 || orf19.3923 || PGA37 || || Putative GPI-anchored protein; Hap43-repressed; Spider biofilm induced || 1 1.19 0.94 0.48 0.80 0.36 -1.27 0.81 0.05 0.63 0.56 0.23 -1.20 0.44 0.74 -0.48 -0.81
2014 || orf19.7093 || HGT13 || || Predicted sugar transporter, involved in glycerol utilization; member of the major facilitator superfamily; 12 transmembrane; gene has intron; oxidative stress-induced via Cap1p; expressed in rich medium, 2% glucose || 1 0.55 0.44 -0.30 0.27 0.18 -1.27 0.38 -0.12 0.28 1.28 -0.02 -0.54 0.52 -0.41 -0.37 -0.15
2015 || orf19.815 || DCK1 || || Putative guanine nucleotide exchange factor; required for embedded filamentous growth; activates Rac1; has a DOCKER domain; similar to adjacent DCK2 and to S. cerevisiae Ylr422wp; regulated by Nrg1; Spider biofilm induced || 1 0.46 0.64 -0.09 0.42 -0.70 -0.94 0.02 -0.06 0.47 0.61 -0.44 -0.36 -0.10 -0.02 -0.37 -0.08
2016 || orf19.244 || DCG1 || || Protein of unknown function; ortholog of S. cerevisiae Dcg1; transcript regulated by Nrg1 and Mig1 || 1 0.21 0.23 0.18 0.65 0.03 -0.84 0.10 0.68 0.30 0.86 -0.28 -0.43 -0.10 -0.01 0.00 -0.04
2017 || orf19.2317 || || || Protein of unknown function; induced by alpha pheromone in SpiderM medium || 1 0.77 0.98 0.09 1.46 0.26 -2.73 0.17 0.89 1.69 2.11 -0.43 -0.44 -0.11 -0.35 0.05 -0.68
2018 || orf19.7298 || CHS2 || || Chitin synthase; nonessential; required for wild-type chitin deposition in hyphae; transcript regulated during dimorphic transition; Chs1 and Chs2, but not Chs3, are inhibited by the protoberberine HWY-289; flow model biofilm repressed || 1 0.17 0.15 0.18 0.46 -0.35 -1.20 0.30 0.16 0.56 0.53 -0.03 -0.08 0.15 0.09 0.01 -0.15
2019 || orf19.7455 || || || Ortholog of C. dubliniensis CD36 : Cd36_86630 and Candida tropicalis MYA-3404 : CTRG_05698 || 1 0.62 0.91 0.54 1.10 -0.74 -2.62 0.56 0.14 1.75 0.53 -0.44 -1.27 0.66 -0.54 -0.88 -1.01
2020 || orf19.7455 || || || Ortholog of C. dubliniensis CD36 : Cd36_86630 and Candida tropicalis MYA-3404 : CTRG_05698 || 1 0.29 0.34 0.05 0.83 0.33 -2.14 0.93 0.19 1.64 0.64 -0.81 -1.33 1.04 0.13 -0.33 -1.15
2021 || orf19.305 || || || Protein of unknown function; upregulated in a cyr1 null mutant || 1 -0.04 0.09 0.10 -0.04 -0.07 -0.86 -0.10 -0.24 0.53 0.19 -0.23 -0.49 0.37 0.11 -0.08 -0.51
2022 || orf19.4070 || || || Ortholog of C. dubliniensis CD36 : Cd36_23270 || 1 0.17 0.35 0.79 0.32 -0.77 0.45 0.24 1.37 1.11 -0.46 1.17 -0.37 0.30 -1.08
2023 || orf19.2891 || || || Ortholog(s) have role in cellular response to oxidative stress, misfolded or incompletely synthesized protein catabolic process, protein import into peroxisome matrix and mitochondrial inner membrane localization || 1 0.59 0.24 0.29 0.16 -0.76 -1.11 0.34 -0.08 0.70 0.41 -0.15 0.51 0.80 0.16 0.30 -0.45
2024 || orf19.5098 || NTG1 || || Protein with strong similarity to both S. cerevisiae Ntg1 and Ntg2 DNA repair glycosylases; transcript induced by iron; Hap43-repressed gene; Spider biofilm induced || 1 -0.02 0.03 0.06 -0.08 -0.43 -0.93 0.63 0.49 0.85 0.45 -0.12 0.31 0.18 0.28 0.39 -0.49
2025 || orf19.7017 || YOX1 || || Putative homeodomain-containing transcription factor; transcriptional repressor; periodic mRNA expression, peak at cell-cycle G1/S phase || 1 0.53 0.94 0.04 0.21 -1.02 -2.02 1.40 1.98 0.99 1.21 0.43 0.54 1.59 0.14 0.61 -1.46
2026 || orf19.3219 || || || Ortholog of S. cerevisiae Sia1; involved in activation of the Pma1 plasma membrane H+-ATPase by glucose in S. cerevisiae; Spider biofilm induced || 1 0.29 0.27 0.15 0.48 -0.57 -1.51 0.23 0.48 0.13 0.31 -0.25 -0.17 0.95 0.40 0.60 -0.33
2027 || orf19.6538 || VMA11 || || Predicted ortholog of S. cerevisiae Tfp3/Vma11; c' subunit of the V0 subcomplex of the vacuolar ATPase; required for hemoglobin-iron utilization; Spider biofilm repressed || 1 0.28 0.46 0.41 0.34 -0.01 -0.82 0.45 0.45 0.51 0.36 0.43 -0.27 0.91 -0.04 0.08 -0.43
2028 || orf19.2274 || || || Ortholog of C. dubliniensis CD36 : Cd36_21450, Candida tropicalis MYA-3404 : CTRG_01739 and Candida albicans WO-1 : CAWG_05814 || 1 0.80 0.35 -0.19 0.49 -0.68 -1.35 0.90 0.70 0.50 0.78 0.48 -0.44 1.56 -0.40 -0.89 -1.07
2029 || orf19.6737 || || || Protein of unknown function; mutants are viable; induced in a cyr1, ras1, or efg1 homozygous null || 1 0.28 0.32 0.68 0.47 0.05 -0.84 0.38 0.43 0.35 0.63 0.14 0.19 0.75 0.17 -0.19 -0.34
2030 || orf19.1825 || || || Protein of unknown function; mutants are viable; filament induced; regulated by Nrg1, Rfg1, Tup1 || 1 0.14 0.12 0.28 0.30 -0.18 -0.88 0.13 0.49 0.28 0.97 0.14 0.22 0.63 0.37 -0.24 -0.24
2031 || orf19.2657 || || || Protein of unknown function || 1 0.02 0.08 0.55 0.30 0.04 -0.66 0.12 0.37 0.38 0.94 -0.07 0.19 0.57 0.58 -0.36 -0.38
2032 || orf19.5166 || DBF4 || || Putative Cdc7p-Dbf4p kinase complex regulatory subunit; Hap43p-induced gene; macrophage/pseudohyphal-repressed; cell-cycle regulated periodic mRNA expression; S. cerevisiae ortholog is not cell-cycle regulated || 1 0.05 0.03 0.59 0.15 0.10 -0.28 0.04 0.32 0.26 0.73 0.13 -0.12 0.45 0.09 -0.09 -0.32
2033 || orf19.1825 || || || Protein of unknown function; mutants are viable; filament induced; regulated by Nrg1, Rfg1, Tup1 || 1 0.19 0.21 0.31 0.19 0.15 -0.23 0.34 0.68 0.67 1.52 0.12 0.04 0.65 0.71 -0.46 0.23
2034 || orf19.1959 || || || Ortholog(s) have ubiquitin-specific protease activity, role in protein deubiquitination and cytosol, ribosome localization || 1 0.17 0.05 0.35 -0.08 -0.08 -0.38 0.20 0.47 0.56 1.12 0.48 0.53 0.41 0.39 0.38 -0.51
2035 || orf19.3676 || ABP140 || || Ortholog of S. cerevisiae actin-binding protein Abp140; Hap43-induced; F-12/CO2 early biofilm induced || 1 0.09 0.39 0.07 -0.05 -0.31 -0.72 0.16 0.41 -0.01 1.73 0.17 -0.64 0.44 0.42 -0.04 -0.43
2036 || orf19.7127 || TLO16 || || Member of a family of telomere-proximal genes of unknown function; may be spliced in vivo || 1 0.11 -0.01 0.21 0.12 -0.43 -0.31 0.94 1.23 0.29 0.29 -0.67 -0.38 0.40 0.14 -0.52 0.23
2037 || orf19.7323 || CBP1 || || Corticosteroid binding protein; transcription induced at late log-phase or upon adherence to polystyrene; not induced by corticosterone; contains a possible NAD/FAD binding region; regulated by Nrg1, Tup1; Spider biofilm induced || 1 -0.02 -0.04 -0.11 0.16 0.01 -0.01 0.62 0.93 0.59 0.02 0.06 -0.22 -0.14 -0.27 -0.41 0.59
2038 || orf19.5877 || ATF1 || || Putative alcohol acetyltransferase; caspofungin repressed; expression depends on Tac1p || 1 0.03 0.15 0.17 0.31 -0.17 -0.16 0.79 0.54 0.60 -0.84 -0.05 -0.04 -0.02 -0.07 -0.04 0.37
2039 || orf19.1150.1 || || || Ortholog of C. dubliniensis CD36 : Cd36_10990, C. parapsilosis CDC317 : CPAR2_804585, Candida tenuis NRRL Y-1498 : cten_CGOB_00256 and Debaryomyces hansenii CBS767 : DEHA2F10406g || 1 -0.14 0.13 -0.69 0.30 -0.19 -0.17 0.91 0.34 0.46 0.53 -0.11 0.36 -0.07 0.37 -0.01 -0.99
2040 || orf19.3494 || CTF5 || || Predicted component of the kinetochore sub-complex COMA; induced during the mating process; repressed by alpha pheromone in SpiderM medium || 1 0.64 0.85 -0.99 0.91 0.94 -1.11 1.87 -0.34 -0.01 0.98 0.76 0.87 0.86 0.96 0.28 -1.08
2041 || orf19.7261 || GDI1 || || Putative Rab GDP-dissociation inhibitor; GlcNAc-induced protein; Spider biofilm repressed || 1 0.05 0.01 0.02 -0.02 -0.17 -0.07 0.30 0.13 0.19 0.04 0.10 0.00 0.00 0.29 0.16 -0.17
2042 || orf19.2184 || || || Putative fumarylacetoacetate hydrolase; clade-associated gene expression; rat catheter and Spider biofilm repressed || 1 0.05 0.07 0.11 0.10 -0.49 -0.45 0.29 0.50 0.26 -0.01 0.07 -0.15 0.12 0.37 0.18 0.10
2043 || orf19.6109 || TUP1 || || Transcriptional corepressor; represses filamentous growth; regulates switching; role in germ tube induction, farnesol response; in repression pathways with Nrg1, Rfg1; farnesol upregulated in biofilm; rat catheter, Spider biofilm repressed || 1 -0.32 -0.31 0.04 0.23 -0.66 -0.53 0.44 0.55 0.57 0.05 0.35 0.30 -0.07 0.36 0.07 -0.08
2044 || orf19.7022 || || || Ortholog of C. dubliniensis CD36 : Cd36_70850, Candida tenuis NRRL Y-1498 : cten_CGOB_00183, Debaryomyces hansenii CBS767 : DEHA2F22462g and Pichia stipitis Pignal : PICST_60416 || 1 -0.19 -0.05 0.02 -0.05 -0.51 -0.44 0.25 0.59 0.47 0.04 0.03 0.33 0.62 0.90 -0.04 -0.41
2045 || orf19.7022 || || || Ortholog of C. dubliniensis CD36 : Cd36_70850, Candida tenuis NRRL Y-1498 : cten_CGOB_00183, Debaryomyces hansenii CBS767 : DEHA2F22462g and Pichia stipitis Pignal : PICST_60416 || 1 -0.37 -0.19 0.14 0.16 -0.38 -0.36 0.07 0.55 0.62 0.12 -0.03 0.29 0.41 0.98 0.09 -0.12
2046 || orf19.7022 || || || Ortholog of C. dubliniensis CD36 : Cd36_70850, Candida tenuis NRRL Y-1498 : cten_CGOB_00183, Debaryomyces hansenii CBS767 : DEHA2F22462g and Pichia stipitis Pignal : PICST_60416 || 1 -0.46 -0.25 0.19 -0.10 -0.40 -0.37 0.24 0.53 0.89 0.24 0.08 0.13 0.83 1.09 0.04 0.04
2047 || orf19.5954 || || || Ortholog(s) have enzyme activator activity, role in ascospore wall assembly, meiosis I, positive regulation of protein catabolic process and anaphase-promoting complex localization || 1 0.00 -0.29 -0.24 -0.27 -0.43 -0.75 -0.23 -0.28 0.87 0.62 0.22 0.05 0.30 1.03 -0.05
2048 || orf19.7391 || OCH1 || || Alpha-1,6-mannosyltransferase; initiates N-glycan outer chain branch addition; similar to S. cerevisiae Och1p; required for wild-type virulence in mouse intravenous infection; fungal-specific (no human or murine homolog) || 1 -0.09 -0.24 -0.36 0.06 -0.65 -0.59 0.06 0.24 0.12 0.27 0.05 0.06 0.37 0.82 0.31 -0.28
2049 || orf19.6404 || GSH2 || || Putative glutathione synthase; induced in high iron; heavy metal (cadmium) stress-induced || 1 -0.11 -0.11 -0.21 -0.02 -0.67 -0.41 -0.02 -0.04 -0.05 0.33 0.18 0.14 -0.02 0.38 0.13 0.13
2050 || orf19.352 || || || Ortholog of C. dubliniensis CD36 : Cd36_83550, C. parapsilosis CDC317 : CPAR2_404510, Debaryomyces hansenii CBS767 : DEHA2B13794g and Pichia stipitis Pignal : PICST_30078 || 1 0.11 -0.03 0.08 -0.07 -0.61 -0.54 0.20 0.02 -0.04 0.23 0.12 0.16 0.27 0.62 -0.06 0.50
2051 || orf19.352 || || || Ortholog of C. dubliniensis CD36 : Cd36_83550, C. parapsilosis CDC317 : CPAR2_404510, Debaryomyces hansenii CBS767 : DEHA2B13794g and Pichia stipitis Pignal : PICST_30078 || 1 0.14 0.10 0.02 -0.12 -0.34 -0.44 0.15 0.04 -0.02 0.20 0.22 0.16 0.34 0.90 0.00 0.18
2052 || orf19.906 || ROM2 || || Putative GDP/GTP exchange factor; possibly an essential gene, disruptants not obtained by UAU1 method; Spider biofilm induced || 1 0.01 0.01 -0.18 0.00 0.05 -0.16 -0.03 0.02 0.03 0.07 0.20 0.43 0.39 0.44 0.10 -0.16
2053 || orf19.6873.1 || KTI11 || || Zn-ribbon protein; required for synthesis of diphthamide on translation factor eEF2; involved in modification of wobble nucleosides in tRNAs; rat catheter and Spider biofilm induced || 1 -0.30 0.15 -0.75 -0.34 -0.15 -0.31 0.19 -0.41 0.36 0.97 -0.13 1.00 0.89 0.59 -0.10 -0.38
2054 || orf19.6873.1 || KTI11 || || Zn-ribbon protein; required for synthesis of diphthamide on translation factor eEF2; involved in modification of wobble nucleosides in tRNAs; rat catheter and Spider biofilm induced || 1 -0.42 -0.22 -0.12 -0.40 0.06 -0.48 1.04 0.02 0.44 1.05 0.09 0.88 1.11 1.05 0.22 -0.49
2055 || orf19.985 || || || Ortholog(s) have endoplasmic reticulum, ribosome localization || 1 -0.31 -0.31 -0.16 -0.34 -0.09 -0.41 0.42 0.30 0.42 0.56 0.17 0.60 0.72 0.04 0.08 -0.51
2056 || orf19.3473 || || || Ortholog(s) have enzyme activator activity, histone acetyltransferase activity, structural molecule activity || 1 -0.26 -0.11 -0.06 -0.23 -0.27 -0.63 0.07 0.24 0.36 0.27 0.17 0.42 0.49 0.49 -0.02 -0.13
2057 || orf19.4206 || || || Ortholog(s) have crossover junction endodeoxyribonuclease activity || 1 -0.10 -0.20 -0.14 -0.19 -0.01 -0.69 0.25 0.22 0.53 0.42 0.21 0.61 0.50 0.60 -0.02 0.20
2058 || orf19.6662 || || || Putative coenzyme Q (ubiquinone) binding protein; transcript is upregulated in clinical isolates from HIV+ patients with oral candidiasis || 1 -0.36 -0.13 0.03 -0.08 -0.62 -0.82 0.28 -0.03 0.47 0.53 0.04 0.59 0.56 -0.16 -0.12 -0.33
2059 || orf19.1516 || || || Ortholog(s) have ubiquitin-specific protease activity || 1 -0.28 -0.25 -0.38 0.01 -0.13 -0.50 0.18 0.31 0.17 0.41 0.00 0.04 0.38 -0.07 0.05 0.11
2060 || orf19.4755 || KEX2 || || Subtilisin-like protease (proprotein convertase); processes aspartyl proteinase Sap2; required for hyphal growth and wild-type virulence in mice; functional homolog of S. cerevisiae Kex2, which processes alpha-factor; Tup1-repressed || 1 -0.29 0.05 -0.37 -0.18 -0.01 -0.45 0.40 0.37 -0.12 0.72 0.32 -0.15 0.54 0.38 0.10 -0.04
2061 || orf19.949 || || || Ortholog of C. dubliniensis CD36 : Cd36_50420, C. parapsilosis CDC317 : CPAR2_304100, Candida tenuis NRRL Y-1498 : CANTEDRAFT_98299 and Debaryomyces hansenii CBS767 : DEHA2B07634g || 1 -0.11 -0.12 0.02 0.12 0.05 -0.17 -0.13 0.11 -0.01 0.31 0.17 0.27 0.29 0.29 -0.08 0.14
2062 || orf19.5276 || || || Putative nuclear pore-associated protein; Hap43p-induced gene; induced upon low-level peroxide stress; possibly an essential gene, disruptants not obtained by UAU1 method || 1 -0.21 0.12 -0.26 0.14 0.07 0.49 0.31 -0.13 -0.06 0.23 0.48 0.52 0.35 0.59 0.12 -0.35
2063 || orf19.4844 || || || Ortholog(s) have RNA binding, polynucleotide adenylyltransferase activity, protein binding, bridging activity || 1 -0.31 0.01 0.33 0.09 0.09 0.44 0.28 0.05 0.22 0.33 0.55 0.61 0.85 0.43 0.13 -0.27
2064 || orf19.6400 || || || Ortholog(s) have role in inositol metabolic process and cytosol, nuclear envelope localization || 1 0.14 0.10 0.22 -0.03 -0.14 0.07 0.07 0.08 -0.02 0.25 0.45 0.41 0.15 0.45 0.19 -0.19
2065 || orf19.1856 || || || Ortholog(s) have histone deacetylase activity || 1 -0.08 -0.08 0.31 -0.04 -0.43 -0.06 0.18 0.38 0.15 0.43 0.75 0.12 0.53 0.96 0.10 -0.17
2066 || orf19.7051 || || || Maf-like protein; rat catheter biofilm induced || 1 -0.18 0.22 -0.15 0.34 0.41 -0.04 0.71 0.78 -0.39 1.17 1.14 0.06 0.50 1.53 0.77 -0.62
2067 || orf19.7401 || ISW2 || || Ortholog of S. cerevisiae Isw2; an ATPase involved in chromatin remodeling; required for chlamydospore formation; Hap43-induced gene; repressed by high-level peroxide stress || 1 -0.12 -0.18 0.28 -0.02 -0.03 -0.22 -0.05 0.26 0.25 0.46 0.23 0.10 0.34 0.52 -0.00 -0.74
2068 || orf19.5485 || MEC3 || || Putative DNA damage and meiotic pachytene checkpoint protein; increased transcription is observed upon benomyl treatment || 1 -0.16 -0.19 -0.27 0.12 0.41 -0.25 0.54 0.35 0.30 0.31 0.84 0.15 -0.12 0.48 -0.02 -0.40
2069 || orf19.5034 || YBP1 || || Protein involved in response to oxidative stress, binds and stabilizes Cap1p transcription factor in response to H2O2; essential for macrophage killing || 1 -0.14 -0.14 -0.19 -0.31 0.43 0.29 -0.02 0.17 0.47 0.13 0.30 0.68 -0.09 -0.28 0.10 0.42
2070 || orf19.6244 || || || Ortholog of C. dubliniensis CD36 : Cd36_06250, C. parapsilosis CDC317 : CPAR2_206820, Candida tenuis NRRL Y-1498 : CANTEDRAFT_125137 and Debaryomyces hansenii CBS767 : DEHA2G13266g || 1 -0.57 -0.05 -0.11 -0.42 0.07 0.22 0.40 0.23 0.94 0.36 0.86 0.55 0.01 0.03 -0.11 0.61
2071 || orf19.3244 || || || Ortholog(s) have role in mitochondrial respiratory chain complex assembly and mitochondrion localization || 1 0.04 0.19 -0.22 -0.22 0.16 0.04 0.25 0.52 0.52 0.52 0.66 0.79 -0.09 -0.10 0.08 0.60
2072 || orf19.1917 || || || Protein of unknown function; Spider biofilm repressed || 1 -0.11 -0.00 0.03 0.08 0.43 0.20 0.10 0.39 0.21 0.14 0.87 0.46 -0.24 -0.04 -0.07 0.43
2073 || orf19.1406 || || || Ortholog(s) have DNA-directed DNA polymerase activity, role in error-free translesion synthesis, error-prone translesion synthesis and mitochondrion, nuclear chromatin, zeta DNA polymerase complex localization || 1 -0.30 0.07 0.01 0.04 0.76 -0.29 0.43 0.42 0.50 0.25 0.88 0.52 -0.17 0.10 0.34 0.70
2074 || orf19.7438 || UBA1 || || Ubiquitin-activating enzyme; protein level decreases in stationary phase cultures || 1 -0.13 -0.10 0.18 0.20 0.34 0.19 0.43 0.38 0.27 0.41 0.42 0.46 -0.22 0.05 0.36 0.15
2075 || orf19.92 || || || Protein with a predicted thioredoxin-like domain; Hap43-repressed; induced by prostaglandins || 1 0.57 0.55 0.32 0.31 0.44 0.04 0.63 0.68 0.38 0.70 0.75 0.62 -0.82 -0.46 0.36 0.22
2076 || orf19.6062 || || || Putative TIM23 translocase complex subunit; membrane-localized; Hap43-repressed || 1 0.31 0.24 0.14 0.06 0.23 0.17 0.67 0.74 0.21 0.11 0.62 0.58 -0.44 -0.27 0.28 0.29
2077 || orf19.596.1 || NOP10 || || Small nucleolar ribonucleoprotein; flucytosine induced || 1 0.29 0.26 -0.47 -0.20 1.01 0.60 1.31 1.55 0.18 0.90 1.18 0.58 -0.35 0.41 -0.20 0.62
2078 || orf19.1968 || || || Ortholog of C. dubliniensis CD36 : Cd36_51280, C. parapsilosis CDC317 : CPAR2_501840, Candida tenuis NRRL Y-1498 : cten_CGOB_00020 and Debaryomyces hansenii CBS767 : DEHA2F24310g || 1 0.13 0.47 -0.49 0.38 0.64 0.42 0.73 0.37 0.11 0.41 0.80 -0.77 0.05 0.14 0.28
2079 || orf19.4195 || || || Ortholog of C. dubliniensis CD36 : Cd36_60540, C. parapsilosis CDC317 : CPAR2_602830, Candida tenuis NRRL Y-1498 : CANTEDRAFT_108530 and Debaryomyces hansenii CBS767 : DEHA2F15532g || 1 -0.54 0.52 -0.64 -0.21 0.60 -0.45 0.56 0.53 0.27 0.44 0.69 0.53 -0.15 -0.47 0.71 0.30
2080 || orf19.6573 || BEM2 || || Putative Rho1p GTPase activating protein (GAP); serum-induced transcript; Spider biofilm induced; flow model biofilm repressed || 1 -0.15 0.21 -0.55 0.27 0.47 0.00 0.35 0.61 -0.18 0.58 1.08 0.49 0.18 -0.07 1.37 0.25
2081 || orf19.5012 || || || Ortholog of C. dubliniensis CD36 : Cd36_12740, C. parapsilosis CDC317 : CPAR2_201620, Candida tenuis NRRL Y-1498 : CANTEDRAFT_107586 and Debaryomyces hansenii CBS767 : DEHA2D04994g || 1 0.77 0.69 -0.93 -0.36 -0.70 -0.08 1.26 0.52 -0.33 1.50 1.29 0.72 0.65 1.11 -0.71
2082 || orf19.513 || || || Protein with a DNA-binding domain, similar to S. cerevisiae meiosis-specific transcription factor Ndt80p || 1 0.48 0.57 -1.17 -0.02 -0.39 0.17 0.32 0.05 1.29 0.09 0.76 0.98 -0.20
2083 || orf19.6776 || GCD2 || || Putative translation initiation factor; genes encoding ribosomal subunits, translation factors, and tRNA synthetases are downregulated upon phagocytosis by murine macrophage || 1 0.19 0.20 -0.38 -0.38 0.11 0.07 0.18 0.25 0.12 0.86 0.28 0.17 0.28 0.17 0.16 0.09
2084 || orf19.6309 || MSS11 || || Transcription factor; activator that binds to Flo8 via a LisH motif to cooperatively activate transcription of hypha-specific genes; required for hyphal growth || 1 0.00 0.05 -0.26 0.03 0.28 -0.20 -0.11 0.14 0.08 0.06 0.37 0.03 0.55 0.35 0.21 -0.04
2085 || orf19.1041 || || || Ortholog(s) have cyclin-dependent protein serine/threonine kinase activity || 1 0.03 0.29 -0.28 -0.60 0.35 -0.00 0.38 0.38 0.09 0.40 1.29 0.09 1.40 0.15 0.30 -0.08
2086 || orf19.6436 || || || Ortholog of C. dubliniensis CD36 : Cd36_34210, C. parapsilosis CDC317 : CPAR2_205590, Candida tenuis NRRL Y-1498 : cten_CGOB_00133 and Debaryomyces hansenii CBS767 : DEHA2E02178g || 1 0.54 0.22 -0.40 -0.15 0.01 -0.55 0.37 0.33 0.01 0.35 0.51 -0.22 0.12 0.33 0.16 -0.22
2087 || orf19.1605 || PMS1 || || Putative DNA mismatch repair factor; ortholog of S. cerevisiae PMS1 which is an ATP-binding protein involved in DNA mismatch repair || 1 0.70 0.31 -0.42 0.60 -0.03 -0.72 0.24 0.62 -0.05 1.23 1.22 0.27 -0.04 0.39 -0.15 0.02
2088 || orf19.2796 || || || Ortholog(s) have DNA-directed DNA polymerase activity, role in DNA replication initiation, telomere capping and alpha DNA polymerase:primase complex, cytosol, nuclear envelope localization || 1 0.34 0.69 0.05 0.44 0.33 -0.87 0.52 1.14 -0.27 0.86 1.13 -0.41 0.05 0.44 0.03 -0.04
2089 || orf19.658 || GIN1 || || Protein involved in regulation of DNA-damage-induced filamentous growth; putative component of DNA replication checkpoint; ortholog of S. cerevisiae Mrc1p, an S-phase checkpoint protein; Hap43p-induced gene || 1 0.47 0.58 -0.52 0.14 -0.13 -2.06 1.08 1.50 -0.31 1.01 1.77 -0.41 0.73 0.96 -0.08 -0.21
2090 || orf19.658 || GIN1 || || Protein involved in regulation of DNA-damage-induced filamentous growth; putative component of DNA replication checkpoint; ortholog of S. cerevisiae Mrc1p, an S-phase checkpoint protein; Hap43p-induced gene || 1 0.50 0.28 -0.07 0.18 0.26 -1.67 0.18 1.27 -0.44 0.87 1.09 -0.33 0.01 0.77 -0.67 -0.12
2091 || orf19.1605 || PMS1 || || Putative DNA mismatch repair factor; ortholog of S. cerevisiae PMS1 which is an ATP-binding protein involved in DNA mismatch repair || 1 0.46 0.48 -0.23 -0.05 0.32 -1.71 0.26 0.90 -0.38 1.01 1.50 0.50 -0.25 0.11 -0.47 0.19
2092 || orf19.4089 || SGT1 || || Putative co-chaperone protein with a predicted role in kinetochore assembly; mutation confers hypersensitivity to radicicol; sumoylation target || 1 0.31 0.40 -0.13 -0.09 0.32 -1.08 0.50 0.88 0.06 0.68 0.60 0.02 -0.16 0.18 -0.16 0.16
2093 || orf19.4089 || SGT1 || || Putative co-chaperone protein with a predicted role in kinetochore assembly; mutation confers hypersensitivity to radicicol; sumoylation target || 1 0.28 0.31 -0.27 -0.07 0.34 -0.76 0.55 0.91 0.07 0.75 0.70 0.25 -0.40 0.49 -0.36 0.12
2094 || orf19.7061 || || || Ortholog(s) have ATPase activity and cytosol, nucleus localization || 1 -0.20 0.37 -0.37 -0.07 0.15 -0.64 0.83 0.58 0.48 0.04 0.77 0.37 0.16 0.45 -0.14 0.51
2095 || orf19.7328 || || || Protein with a Staphylococcal nuclease domain; transcript regulated by Mig1 and Tup1; flow model and Spider biofilm repressed || 1 -0.12 0.24 -0.71 -0.49 0.38 -0.96 0.39 0.71 0.43 0.22 0.54 0.34 0.50 0.32 -0.05 0.64
2096 || orf19.3264 || CCE1 || || Putative Holliday junction resolving enzyme; similar to S. cerevisiae Cce1p || 1 0.44 -0.29 -0.37 -0.41 -0.03 -0.63 0.41 0.39 0.17 0.43 1.05 0.57 0.32 0.16 -0.21 0.29
2097 || orf19.926 || EXO1 || || Putative exodeoxyribonuclease; cell-cycle regulated periodic mRNA expression || 1 0.60 0.35 -0.32 -0.64 0.27 -0.51 0.73 0.52 -0.22 0.68 2.07 0.29 0.97 1.08 -0.36 1.26
2098 || orf19.926 || EXO1 || || Putative exodeoxyribonuclease; cell-cycle regulated periodic mRNA expression || 1 0.34 0.35 -0.51 -0.63 0.05 -0.93 0.50 0.91 -0.42 0.21 1.36 -0.04 0.58 0.69 -0.32 0.48
2099 || orf19.1429 || SOH1 || || Subunit of the RNA polymerase II mediator complex; involved in control of cytokinesis, morphogenesis, biofilm formation, virulence; cell-cycle regulated periodic mRNA expression || 1 0.38 0.18 -0.15 -0.04 0.34 -1.10 0.47 0.96 -0.26 0.29 0.77 -0.20 1.00 0.32 0.62 -0.04
2100 || orf19.6479 || SEC1 || || Ortholog(s) have SNARE binding activity and role in positive regulation of vesicle fusion, vesicle docking involved in exocytosis || 1 0.15 0.16 -0.40 -0.10 -0.12 -0.67 0.91 0.76 0.14 0.14 0.77 0.02 0.73 0.10 0.46 -0.58
2101 || orf19.247 || || || Ortholog(s) have role in endosome organization, regulation of protein localization and BLOC-1 complex, endosome localization || 1 -0.13 -0.28 -0.18 -0.24 -0.85 -0.71 0.81 0.50 0.55 0.04 0.78 0.24 0.55 0.40 0.43 0.86
2102 || orf19.1502 || || || Has domain(s) with predicted aminoacyl-tRNA hydrolase activity || 1 0.54 0.13 0.17 0.23 -0.47 -0.46 0.81 0.66 0.62 -0.20 1.16 0.64 0.38 0.36 0.12 1.03
2103 || orf19.1522 || || || Ortholog of C. dubliniensis CD36 : Cd36_16850, C. parapsilosis CDC317 : CPAR2_211990, Candida tenuis NRRL Y-1498 : cten_CGOB_00169 and Debaryomyces hansenii CBS767 : DEHA2G03036g || 1 0.41 0.09 -0.39 0.11 -0.87 -0.67 0.48 0.79 -0.11 -0.01 0.81 0.88 0.85 0.71 0.04 1.07
2104 || orf19.6326 || || || Ortholog of C. dubliniensis CD36 : Cd36_60130, C. parapsilosis CDC317 : CPAR2_603380, Candida tenuis NRRL Y-1498 : CANTEDRAFT_94402 and Debaryomyces hansenii CBS767 : DEHA2G06556g || 1 0.25 0.38 -0.17 0.25 -0.86 -0.48 0.42 0.95 -0.09 0.50 0.80 0.14 0.33 0.04 -0.31 0.17
2105 || orf19.6326 || || || Ortholog of C. dubliniensis CD36 : Cd36_60130, C. parapsilosis CDC317 : CPAR2_603380, Candida tenuis NRRL Y-1498 : CANTEDRAFT_94402 and Debaryomyces hansenii CBS767 : DEHA2G06556g || 1 0.28 0.32 -0.26 0.17 -0.82 -0.38 0.61 0.88 0.15 0.66 0.90 0.38 0.40 0.26 -0.13 0.32
2106 || orf19.4725 || SWI6 || || Putative component of the MBF and SBF transcription complexes involved in G1/S cell-cycle progression; periodic mRNA expression, peak at cell-cycle G1/S phase || 1 0.31 0.64 0.70 0.53 -1.23 1.12 0.74 0.04 1.29 1.28 0.33 0.66 0.48 -0.44 0.31
2107 || orf19.4603 || ARL1 || || Putative GTPase; mutation confers dose-dependent sensitivity to Brefeldin A || 1 0.02 0.27 0.55 0.17 -0.43 -0.49 0.23 0.31 0.20 0.63 0.64 0.47 0.24 0.18 -0.09 0.21
2108 || orf19.2975 || YPT7 || || Protein of YPT/RAB family; induced during the mating process || 1 0.22 0.25 0.22 0.22 -0.32 -0.51 0.08 0.29 0.31 0.27 0.22 0.34 0.46 0.20 -0.13 0.13
2109 || orf19.5268 || MED10 || || RNA polymerase II mediator complex subunit; possibly an essential gene, disruptants not obtained by UAU1 method || 1 0.34 0.20 0.45 0.34 -0.44 -0.72 0.55 0.79 0.38 0.32 0.70 0.27 1.00 0.73 -0.03 0.03
2110 || orf19.3453 || || || Ortholog(s) have cellular bud tip, cytoplasm localization || 1 0.34 0.38 0.43 0.39 -0.25 -0.88 0.86 0.77 0.64 0.33 0.45 0.40 0.48 0.42 -0.52 0.26
2111 || orf19.1964 || || || Protein of unknown function; repressed by fluphenazine treatment; induced by benomyl treatment and in an RHE model; regulated by Nrg1, Tup1 || 1 0.51 0.19 0.73 0.47 -0.36 -0.70 0.53 0.44 0.41 -0.02 0.22 0.27 0.89 0.07 -0.32 0.41
2112 || orf19.4557 || || || Ortholog(s) have microtubule binding, structural constituent of cytoskeleton activity and role in microtubule nucleation, mitotic spindle assembly checkpoint, protein localization to kinetochore, sister chromatid biorientation || 1 1.24 0.87 0.86 1.25 -0.96 -1.04 0.52 0.81 0.60 0.26 0.62 -0.04 1.13 0.33 -0.12 0.00
2113 || orf19.4623.3 || NHP6A || || Putative non-histone chromatin component; RNA abundance regulated by tyrosol,cell density; Hap43-induced; amphotericin B, caspofungin repressed; 5'-UTR intron; rat catheter and Spider biofilm repressed || 1 0.84 0.68 0.99 1.38 -1.17 -0.76 1.31 1.80 0.42 0.01 2.14 1.10 1.53 0.45 0.26 0.53
2114 || orf19.4623.3 || NHP6A || || Putative non-histone chromatin component; RNA abundance regulated by tyrosol,cell density; Hap43-induced; amphotericin B, caspofungin repressed; 5'-UTR intron; rat catheter and Spider biofilm repressed || 1 0.57 0.61 0.79 1.20 -1.32 -0.91 1.02 1.39 0.27 -0.01 2.06 0.97 1.51 0.42 0.31 0.60
2115 || orf19.4623.3 || NHP6A || || Putative non-histone chromatin component; RNA abundance regulated by tyrosol,cell density; Hap43-induced; amphotericin B, caspofungin repressed; 5'-UTR intron; rat catheter and Spider biofilm repressed || 1 0.61 0.63 0.84 1.20 -1.30 -0.87 1.15 1.37 0.28 -0.08 2.13 0.99 1.53 0.42 0.27 0.67
2116 || orf19.4623.3 || NHP6A || || Putative non-histone chromatin component; RNA abundance regulated by tyrosol,cell density; Hap43-induced; amphotericin B, caspofungin repressed; 5'-UTR intron; rat catheter and Spider biofilm repressed || 1 0.58 0.58 0.81 0.98 -1.22 -0.89 1.27 1.50 0.27 0.00 2.08 0.95 1.42 0.53 0.45 0.81
2117 || orf19.7377 || ASE1 || || Putative microtubule-associated protein; member of conserved Mcm1p regulon; periodic mRNA expression, peak at cell-cycle G2/M phase || 1 0.69 0.65 0.32 0.41 0.06 -0.77 0.79 0.59 0.04 0.05 0.85 -0.01 1.35 0.21 -0.22 0.19
2118 || orf19.6644 || || || Protein of unknown function; 2 predicted transmembrane domains; transcript detected on high-resolution tiling arrays; flow model biofilm induced; Spider biofilm repressed || 1 0.50 0.40 0.11 0.22 -0.28 -0.69 0.65 0.36 -0.30 -0.56 0.81 0.15 0.62 0.28 -0.03 0.83
2119 || orf19.6645 || HMO1 || || HMG-box transcription factor; binds upstream of hexose and ergosterol metabolism and cell cycle genes; activates pseudohyphal growth when expressed in S. cerevisiae; repressed in hyphae; Spider biofilm repressed || 1 0.36 0.42 0.24 0.24 -0.15 -0.67 0.44 0.69 -0.09 -0.43 0.71 0.19 0.62 0.27 -0.18 0.55
2120 || orf19.4444 || PHO15 || || 4-nitrophenyl phosphatase, possible histone H2A phosphatase; involved in regulation of white-opaque switch; hyphal repressed; induced in core stress response; induced by cadmium stress via Hog1; rat catheter and Spider biofilm repressed || 1 0.51 1.23 0.13 0.39 -0.50 -0.90 0.67 0.77 0.13 -0.62 0.52 -0.12 0.50 0.30 -0.63 0.52
2121 || orf19.564 || KAR3 || || Kinesin-like microtubule motor protein; required for nuclear fusion during mating; C-terminal motor domain; mutants are viable; null has high-frequency white-opaque switching phenotype || 1 0.38 0.78 0.30 0.42 -0.27 -0.89 0.30 0.57 -0.23 0.27 0.40 0.41 0.48 0.52 -0.24 0.12
2122 || orf19.4675 || ASK1 || || Essential subunit of the Dam1 (DASH) complex, which acts in chromosome segregation by coupling kinetochores to spindle microtubules || 1 0.79 0.80 0.55 0.26 -0.17 -0.80 0.62 0.85 0.17 0.18 1.45 1.16 0.68 0.78 -0.37 0.59
2123 || orf19.4675 || ASK1 || || Essential subunit of the Dam1 (DASH) complex, which acts in chromosome segregation by coupling kinetochores to spindle microtubules || 1 0.87 0.64 0.24 0.08 -0.65 -1.28 0.64 0.71 -0.42 -0.10 0.96 0.79 0.80 0.26 -0.48 0.61
2124 || orf19.2328 || || || Ortholog of C. dubliniensis CD36 : Cd36_10220, C. parapsilosis CDC317 : CPAR2_210530, Candida tenuis NRRL Y-1498 : CANTEDRAFT_105553 and Debaryomyces hansenii CBS767 : DEHA2G14432g || 1 0.42 0.37 0.06 -0.09 -0.35 -1.10 0.44 0.61 -0.31 0.04 0.63 0.45 0.16 0.41 -0.03 0.23
2125 || orf19.2437 || ARC35 || || Putative ARP2/3 complex subunit; shows colony morphology-related gene regulation by Ssn6p; mutation confers hypersensitivity to cytochalasin D || 1 0.62 0.54 0.11 -0.06 -0.36 -1.02 0.55 1.14 0.34 -0.03 1.00 0.34 0.38 0.10 -0.18 0.22
2126 || orf19.1202 || || || Ortholog of C. dubliniensis CD36 : Cd36_60350, C. parapsilosis CDC317 : CPAR2_603550, Candida tenuis NRRL Y-1498 : CANTEDRAFT_114325 and Debaryomyces hansenii CBS767 : DEHA2G04950g || 1 0.88 0.86 -0.31 -0.11 -0.71 -1.43 0.60 1.00 -0.12 0.51 0.98 0.15 0.52 0.78 -0.89 0.31
2127 || orf19.4325 || || || Ortholog of C. dubliniensis CD36 : Cd36_52760, C. parapsilosis CDC317 : CPAR2_303150, Candida tenuis NRRL Y-1498 : CANTEDRAFT_133407 and Debaryomyces hansenii CBS767 : DEHA2G08030g || 1 0.58 0.67 -0.15 -0.12 -0.50 -0.91 0.62 0.92 0.02 0.30 0.41 -0.17 0.77 0.65 -0.84 0.14
2128 || orf19.4325 || || || Ortholog of C. dubliniensis CD36 : Cd36_52760, C. parapsilosis CDC317 : CPAR2_303150, Candida tenuis NRRL Y-1498 : CANTEDRAFT_133407 and Debaryomyces hansenii CBS767 : DEHA2G08030g || 1 0.50 0.59 -0.25 -0.05 -0.34 -0.59 0.39 0.52 -0.34 0.06 0.31 0.08 0.81 0.20 -0.51 0.59
2129 || orf19.2876 || CBF1 || || Transcription factor; binds ribosomal protein gene promoters and rDNA locus with Tbf1; regulates sulfur starvation-response, respiratory, glycolytic genes; does not bind to centromeres as does S. cerevisiae Cbf1; Spider biofilm repressed || 1 1.17 1.48 -0.42 -0.54 -0.52 -0.62 1.12 1.07 0.11 0.07 0.90 0.14 1.08 0.60 -0.98 1.27
2130 || orf19.2529 || || || Ortholog of S. cerevisiae Gpa15; involved in the synthesis of glycosylphosphatidylinositol (GPI) anchors; shuman Pig-H, which is also involved in GPI assembly; Spider biofilm induced || 1 0.41 0.26 -0.15 -0.01 -0.53 -0.41 0.39 0.32 -0.09 -0.17 0.26 0.17 0.30 0.09 -0.27 0.26
2131 || orf19.2598 || VMA4 || || H+ transporting ATPase E chain; transcript regulated by Mig1; caspofungin repressed; protein level decreases in stationary phase cultures; rat catheter biofilm repressed || 1 0.75 0.56 -0.17 -0.28 -0.11 -0.33 0.56 0.38 -0.06 -0.08 0.45 0.05 0.26 0.18 0.04 0.07
2132 || orf19.6771 || UBI4 || || Ubiquitin precursor (polyubiquitin) contains 3 tandem repeats of the ubiquitin peptide that are processed to individual units; transcript induced by stress; mRNA in yeast and mycelia at similar abundance; Spider biofilm induced || 1 1.26 1.21 0.45 0.24 -0.27 -0.48 0.85 0.51 0.06 0.06 0.50 -0.06 0.91 0.54 -0.44 -0.05
2133 || orf19.2876 || CBF1 || || Transcription factor; binds ribosomal protein gene promoters and rDNA locus with Tbf1; regulates sulfur starvation-response, respiratory, glycolytic genes; does not bind to centromeres as does S. cerevisiae Cbf1; Spider biofilm repressed || 1 1.63 1.64 0.09 -0.09 -0.24 -0.47 1.12 1.15 0.19 -0.15 0.96 -0.38 1.22 0.68 -0.60 0.57
2134 || orf19.6509 || || || Ortholog(s) have role in cellular response to zinc ion and cytosol, nucleus localization || 1 1.08 0.98 0.00 0.05 -0.97 -0.67 0.77 1.01 0.08 -0.07 0.78 -0.10 0.44 0.55 -0.04 0.45
2135 || orf19.6220.3 || MMD1 || || Mitochondrial protein; possibly required for transamination of isoleucine; macrophage-downregulated protein abundance; rat catheter and Spider biofilm repressed || 1 1.02 0.97 0.21 0.47 -0.65 -0.48 0.56 0.51 0.25 0.14 0.64 0.36 0.37 0.22 0.23 0.22
2136 || orf19.36 || || || Component of the conserved oligomeric Golgi complex; predicted to mediate fusion of transport vesicles to Golgi compartments; clade-associated gene expression || 1 0.31 0.28 0.16 -0.14 -0.12 -0.54 0.42 0.11 -0.07 0.18 1.11 0.99 0.59 0.43 0.62 0.49
2137 || orf19.1273 || || || Ortholog(s) have tubulin binding activity, role in tubulin complex assembly and prefoldin complex localization || 1 0.57 0.61 0.46 0.16 -0.28 -0.27 0.19 0.30 0.37 0.47 0.92 0.64 0.70 0.45 0.34 0.94
2138 || orf19.5488 || || || Ortholog(s) have mitochondrion localization || 1 1.08 0.67 0.25 0.22 -0.64 -1.32 1.07 0.25 -0.08 1.16 1.61 0.88 1.33 1.22 0.34 1.73
2139 || orf19.2615 || MDL1 || || Putative mitochondrial, half-size MDR-subfamily ABC transporter || 1 0.37 0.11 0.49 -0.08 -0.10 -0.66 0.36 0.59 -0.05 0.11 0.75 0.50 0.43 0.74 0.32 0.73
2140 || orf19.5929 || || || Putative protein of unknown function, transcription is positively regulated by Tbf1p || 1 0.33 0.51 0.54 0.05 -0.09 -0.74 0.84 0.78 0.31 -0.05 1.09 0.66 0.77 0.89 0.75 0.70
2141 || orf19.6246 || || || Ortholog(s) have peptide alpha-N-acetyltransferase activity, role in N-terminal peptidyl-methionine acetylation, cytoskeleton organization, mitochondrion inheritance and NatB complex, cytosol, nucleus localization || 1 0.11 0.13 0.09 -0.20 -0.21 -0.41 0.52 0.55 0.49 0.05 0.74 0.74 0.40 0.81 0.49 0.81
2142 || orf19.1711 || END3 || || Regulated by Gcn4p; induced in response to amino acid starvation (3-aminotriazole treatment) || 1 0.19 0.20 0.11 0.05 -0.35 -0.33 0.50 0.49 0.44 0.34 0.64 0.38 0.32 0.56 0.72 0.54
2143 || orf19.729 || || || Adaptor protein required for specific mRNA transport; protein similar but not orthologous to S. cerevisiae She3; transposon mutation affects filamentous growth || 1 0.48 0.49 -0.15 -0.10 -0.08 -0.32 0.23 0.65 0.25 0.10 0.73 0.34 0.19 0.11 0.37 0.47
2144 || orf19.7017 || YOX1 || || Putative homeodomain-containing transcription factor; transcriptional repressor; periodic mRNA expression, peak at cell-cycle G1/S phase || 1 1.28 0.97 0.66 0.44 -0.25 -1.60 2.02 1.81 0.89 0.81 1.69 0.52 1.75 0.10 0.98 -0.73
2145 || orf19.6033 || CMP1 || || Catalytic subunit of calcineurin (Ca[2+]-calmodulin-regulated S/T protein phosphatase); required for wild-type virulence, resistance to high pH, Na(+), Li(+), Mn(2+), and fluconazole tolerance; micafungin is fungicidal to null mutant || 1 0.25 0.02 0.03 0.07 -0.01 -0.23 0.51 0.83 0.14 0.34 0.32 0.07 0.40 0.25 0.39 0.38
2146 || orf19.6901 || || || Ortholog(s) have exoribonuclease activator activity, m7G(5')pppN diphosphatase activity || 1 0.22 0.17 0.14 -0.08 -0.13 -0.43 0.21 0.51 -0.10 0.11 0.15 0.05 0.54 0.29 0.20 0.20
2147 || orf19.5735 || CDC50 || || Putative endosomal protein; induced by Mnl1p under weak acid stress || 1 0.30 0.17 -0.08 -0.12 -0.18 -0.60 0.35 0.66 0.01 0.12 0.19 0.19 0.39 0.29 0.32 0.05
2148 || orf19.645.1 || VMA13 || || Predicted proton-transporting ATPase; predicted role in ATP hydrolysis coupled proton transport; rat catheter biofilm repressed || 1 0.29 0.29 -0.00 -0.01 -0.44 -0.56 0.43 0.53 0.39 0.13 0.27 0.13 0.64 0.26 0.19 0.26
2149 || orf19.3453 || || || Ortholog(s) have cellular bud tip, cytoplasm localization || 1 0.40 0.33 -0.38 -0.09 -0.70 -1.13 1.02 1.08 0.63 0.59 0.43 0.24 0.71 0.62 -0.23 0.46
2150 || orf19.6712 || || || Ortholog(s) have COPI-coated vesicle, Golgi apparatus localization || 1 0.45 0.24 -0.31 -0.32 -0.35 -0.99 0.80 0.73 0.26 0.09 0.42 -0.09 0.68 0.36 0.14 0.20
2151 || orf19.519 || || || Ortholog(s) have RNA polymerase I upstream control element sequence-specific DNA binding, RNA polymerase I upstream control element sequence-specific DNA binding transcription factor activity || 1 0.84 0.41 -0.31 0.00 -0.37 -0.74 0.75 0.62 0.34 0.17 0.51 -0.19 0.29 0.44 0.22 0.29
2152 || orf19.1715 || IRO1 || || Putative transcription factor; role in iron utilization, pathogenesis; both IRO1 and adjacent URA3 are mutated in strain CAI4; suppresses S. cerevisiae aft1 mutant low-iron growth defect; hyphal-induced; reports differ about iron regulation || 1 0.64 0.82 -0.18 0.10 -0.14 -1.10 1.15 0.88 0.31 0.39 0.17 -0.51 0.89 0.33 0.07 0.56
2153 || orf19.6132 || || || Ortholog of C. dubliniensis CD36 : Cd36_33000, C. parapsilosis CDC317 : CPAR2_701740, Candida tenuis NRRL Y-1498 : CANTEDRAFT_93887 and Debaryomyces hansenii CBS767 : DEHA2E04554g || 1 0.90 0.81 -0.01 -0.10 -0.01 -0.26 0.67 0.94 0.01 0.34 0.35 -0.22 0.42 0.46 0.27 0.01
2154 || orf19.909.1 || || || Ortholog of C. dubliniensis CD36 : Cd36_17965, C. parapsilosis CDC317 : CPAR2_211700, Candida tenuis NRRL Y-1498 : CANTEDRAFT_112898 and Debaryomyces hansenii CBS767 : DEHA2G05588g || 1 0.55 1.00 -0.34 -0.27 -0.01 -0.32 1.48 1.52 0.01 0.10 0.64 -0.38 0.99 0.74 0.33 -0.21
2155 || orf19.909.1 || || || Ortholog of C. dubliniensis CD36 : Cd36_17965, C. parapsilosis CDC317 : CPAR2_211700, Candida tenuis NRRL Y-1498 : CANTEDRAFT_112898 and Debaryomyces hansenii CBS767 : DEHA2G05588g || 1 1.22 1.17 -0.14 0.04 0.11 -0.12 1.60 1.70 0.31 0.11 0.76 -0.16 1.07 0.86 0.49 -0.04
2156 || orf19.3154 || || || Ortholog(s) have mitochondrial membrane localization || 1 0.65 0.50 0.02 0.06 -0.14 -0.23 1.08 0.92 0.22 0.27 0.23 -0.15 1.03 0.45 0.26 -0.09
2157 || orf19.3505 || || || Ortholog(s) have role in TOR signaling cascade, actin filament bundle assembly, eisosome assembly, endosomal transport, establishment or maintenance of actin cytoskeleton polarity, regulation of cell growth || 1 0.58 0.73 -0.47 -0.50 0.44 -0.51 1.11 0.74 -0.16 -0.22 0.85 -0.26 1.46 0.61 0.74 0.43
2158 || orf19.4085 || || || Protein of unknown function; transcript detected on high-resolution tiling arrays || 1 0.19 0.41 -0.15 0.09 0.04 -0.35 0.24 0.46 -0.04 -0.09 0.37 -0.15 0.44 0.28 0.34 0.12
2159 || orf19.4084 || KIS1 || || Snf1p complex scaffold protein; similar to S. cerevisiae Gal83p and Sip2p with regions of similarity to Sip1p (ASC and KIS domain); interacts with Snf4p; mutants are hypersensitive to caspofungin and hydrogen peroxide; Hap43p-repressed gene || 1 0.51 0.56 -0.10 -0.05 -0.22 -0.51 0.54 0.52 -0.06 -0.00 0.68 -0.05 0.90 0.34 0.62 -0.06
2160 || orf19.5735 || CDC50 || || Putative endosomal protein; induced by Mnl1p under weak acid stress || 1 0.46 0.32 -0.02 -0.05 0.09 -0.45 0.45 0.44 0.14 0.18 0.36 0.00 0.64 0.39 0.33 0.13
2161 || orf19.7355 || SSN8 || || Ortholog of S. cerevisiae Ssn8; a component of RNA polymerase II holoenzyme; mutants are viable and are sensitive to hydrogen peroxide medium || 1 0.36 0.46 -0.30 -0.19 -0.25 -0.44 1.19 0.98 0.52 0.38 0.64 0.00 1.30 0.63 0.44 0.38
2162 || orf19.5595 || SHE3 || || mRNA-binding protein that localizes specific mRNAs to daughter yeast cells and to hyphal tips; required for normal filamentation and host epithelial cell damage; ortholog of S. cerevisiae She3 but target mRNAs differs || 1 0.65 0.65 -0.49 -0.28 -0.17 -1.30 1.64 1.61 0.77 0.95 1.14 -0.09 1.30 0.24 0.59 0.39
2163 || orf19.497 || EAF7 || || Subunit of the NuA4 histone acetyltransferase complex || 1 0.27 0.41 -0.03 -0.25 0.22 -0.54 0.89 0.98 0.05 0.39 0.70 0.02 0.73 0.12 0.49 0.22
2164 || orf19.5126 || || || Putative adhesin-like protein || 1 0.68 0.71 -0.76 -0.44 -0.23 -0.92 1.07 0.92 -0.15 1.10 1.16 0.17 1.48 0.18 1.08 -0.09
2165 || orf19.497 || EAF7 || || Subunit of the NuA4 histone acetyltransferase complex || 1 0.22 0.30 -0.69 -0.38 -0.10 -0.38 0.61 0.57 -0.01 0.23 0.54 0.06 0.49 0.26 0.51 0.22
2166 || orf19.2228 || || || Ortholog(s) have actin filament binding, actin monomer binding activity and role in actin cortical patch organization, actin filament depolymerization, actin filament severing, sequestering of actin monomers || 1 0.73 0.46 0.09 -0.60 -0.18 -0.75 1.06 0.84 0.28 0.26 1.30 0.41 0.19 0.54 0.21 0.41
2167 || orf19.3173 || || || Ortholog(s) have Golgi apparatus, endoplasmic reticulum localization || 1 0.33 0.24 -0.09 -0.29 0.13 -0.15 0.71 0.62 0.46 0.40 0.81 0.28 0.59 -0.14 0.33 0.68
2168 || orf19.3173 || || || Ortholog(s) have Golgi apparatus, endoplasmic reticulum localization || 1 0.34 0.42 0.01 0.04 0.05 0.03 0.68 0.74 0.50 0.38 1.00 0.60 0.67 -0.02 0.21 0.39
2169 || orf19.497 || EAF7 || || Subunit of the NuA4 histone acetyltransferase complex || 1 0.37 0.35 -0.19 0.10 0.11 -0.28 0.59 0.62 0.31 0.43 0.61 0.34 0.40 0.01 0.27 0.44
2170 || orf19.4373 || || || Protein similar to S. cerevisiae Fmn1p, which is riboflavin kinase; predicted Kex2p substrate; Hap43p-repressed gene || 1 0.56 0.67 0.00 0.00 -0.32 -0.68 1.31 1.12 0.67 0.75 1.57 0.72 0.93 0.56 0.48 1.12
2171 || orf19.1502 || || || Has domain(s) with predicted aminoacyl-tRNA hydrolase activity || 1 0.78 0.84 0.09 0.25 -0.31 -0.67 1.45 0.96 0.83 0.19 1.61 0.60 0.65 0.38 0.17 0.85
2172 || orf19.2051 || || || Ortholog of C. dubliniensis CD36 : Cd36_15670, C. parapsilosis CDC317 : CPAR2_213100, Candida tenuis NRRL Y-1498 : CANTEDRAFT_135034 and Debaryomyces hansenii CBS767 : DEHA2E14960g || 1 0.71 0.79 -0.23 0.50 -0.53 -0.57 0.92 0.85 0.58 0.55 1.18 0.50 1.06 0.55 0.81 0.33
2173 || orf19.2051 || || || Ortholog of C. dubliniensis CD36 : Cd36_15670, C. parapsilosis CDC317 : CPAR2_213100, Candida tenuis NRRL Y-1498 : CANTEDRAFT_135034 and Debaryomyces hansenii CBS767 : DEHA2E14960g || 1 0.17 0.32 -0.30 0.21 -0.83 -0.55 0.62 0.94 0.46 0.69 0.84 0.38 0.73 0.78 0.40
2174 || orf19.1935 || || || Dubious open reading frame || 1 0.62 0.40 -0.34 -0.31 -1.23 -1.32 0.96 1.58 0.33 0.85 1.85 1.13 0.78 0.20 0.56 0.62
2175 || orf19.4382 || || || Ortholog(s) have role in retrograde vesicle-mediated transport, Golgi to ER and COPI vesicle coat, cytosol, nucleus localization || 1 0.48 0.56 -0.47 -0.13 -0.60 -0.98 0.53 1.14 -0.06 0.27 1.16 0.24 0.29 0.51 0.43 0.41
2176 || orf19.4382 || || || Ortholog(s) have role in retrograde vesicle-mediated transport, Golgi to ER and COPI vesicle coat, cytosol, nucleus localization || 1 0.31 0.39 0.00 0.16 -0.58 -0.80 0.58 0.92 -0.16 0.31 1.08 0.15 0.54 0.37 0.14 0.32
2177 || orf19.6828.1 || || || Ortholog(s) have P-P-bond-hydrolysis-driven protein transmembrane transporter activity, structural molecule activity || 1 0.75 0.81 0.03 -0.11 -0.61 -1.32 1.52 1.88 0.22 0.80 2.00 0.58 1.53 1.05 0.43 0.59
2178 || orf19.6828.1 || || || Ortholog(s) have P-P-bond-hydrolysis-driven protein transmembrane transporter activity, structural molecule activity || 1 0.50 0.50 -0.31 -0.02 -0.95 -1.53 1.30 1.83 0.18 0.40 1.70 0.58 1.25 0.79 0.38 0.18
2179 || orf19.2614 || RSR1 || || RAS-related protein; GTP/GDP cycling required for wild-type polar bud site selection, hyphal growth guidance; role in systemic virulence in mouse; geranylgeranylation predicted; suppresses S. cerevisiae cdc24-4 mutant heat sensitivity || 1 0.95 0.93 -0.43 0.04 -1.46 -1.80 1.50 1.99 0.27 0.66 1.59 0.12 1.50 0.60 0.26 -0.14
2180 || orf19.2614 || RSR1 || || RAS-related protein; GTP/GDP cycling required for wild-type polar bud site selection, hyphal growth guidance; role in systemic virulence in mouse; geranylgeranylation predicted; suppresses S. cerevisiae cdc24-4 mutant heat sensitivity || 1 0.99 1.19 -0.26 0.17 -1.41 -1.50 1.61 2.05 0.61 1.06 1.75 0.54 1.47 1.13 0.50 0.23
2181 || orf19.4930 || SPC3 || || Essential protein; similar to S. cerevisiae Spc3p, a component of the signal peptidase complex required for signal peptidase activity; predicted integral ER membrane protein; complements spc3 and suppresses sec61 S. cerevisiae mutants || 1 1.10 0.93 -0.08 -0.16 -0.15 -1.39 1.12 1.63 0.06 0.79 1.16 0.10 0.79 0.80 0.89 0.09
2182 || orf19.6452 || RBP1 || || Peptidyl-prolyl cis-trans isomerase; rapamycin-binding protein; homozygous null mutation confers rapamycin resistance; regulated by Gcn4p; macrophage-induced protein; repressed in response to 3-AT; functional homolog of S. cerevisiae Rbp1p || 1 0.61 0.50 -0.03 0.03 -0.25 -0.49 0.75 1.00 -0.02 0.08 1.02 -0.11 0.53 0.31 0.38 -0.04
2183 || orf19.6010.1 || RPB11 || || Putative RNA polymerase II subunit; flucytosine induced || 1 0.43 0.46 0.01 0.16 -0.61 -0.97 0.40 0.90 0.02 0.23 1.12 -0.16 0.56 0.09 0.34 -0.06
2184 || orf19.239 || || || Putative ATP-dependent helicase; induced by nitric oxide || 1 0.72 0.67 -0.25 0.09 -0.24 -0.92 0.47 1.00 0.18 0.53 0.86 0.16 0.72 0.34 -0.23 0.18
2185 || orf19.1012 || || || Ortholog(s) have clathrin binding activity, role in Golgi to vacuole transport, endosomal transport and AP-1 adaptor complex, cytosol, endosome, nucleus localization || 1 1.09 0.66 0.41 0.37 -0.89 -0.88 0.92 1.34 0.94 0.48 1.41 0.06 0.69 0.56 -0.21 0.41
2186 || orf19.5817 || || || Ortholog(s) have Rab guanyl-nucleotide exchange factor activity, role in ER to Golgi vesicle-mediated transport, intra-Golgi vesicle-mediated transport and TRAPP complex, cis-Golgi network membrane, cytosol, nucleus localization || 1 0.85 0.81 0.43 0.55 -0.50 -0.75 0.73 1.13 0.49 0.96 1.02 0.37 0.13 0.34 -0.09 0.24
2187 || orf19.5691 || CDC11 || || Septin; cell and hyphal morphology, agar-invasive growth, full virulence and kidney tissue invasion in mouse, but not kidney colonization, immunogenicity; hyphal and cell-cycle-regulated phosphorylation; rat catheter biofilm repressed || 1 0.99 1.03 0.18 0.37 -0.75 -1.30 0.84 1.33 0.05 1.21 1.31 0.15 0.30 0.28 -0.17 0.40
2188 || orf19.731 || EMP46 || || Protein similar to S. cerevisiae Emp46, an integral membrane component of ER-derived COPII-coated vesicles; functions in ER to Golgi transport; induced by alpha pheromone in SpiderM medium || 1 0.71 0.69 -0.09 0.32 -0.57 -1.16 0.93 1.21 0.39 0.49 1.13 0.19 0.29 -0.01 -0.22 -0.01
2189 || orf19.1448.1 || || || Ortholog(s) have plus-end-directed microtubule motor activity || 1 0.72 0.66 0.25 0.34 -0.04 -0.70 0.81 1.28 0.30 0.74 1.35 0.28 0.61 0.13 -0.01 -0.07
2190 || orf19.4837 || DAM1 || || Essential subunit of the Dam1 (DASH) complex, which acts in chromosome segregation by coupling kinetochores to spindle microtubules || 1 1.00 1.22 0.57 0.47 -0.28 -0.78 1.19 1.61 0.29 1.09 1.54 0.87 1.57 0.27 0.51 0.74
2191 || orf19.1666 || || || Ortholog of Dig2, a MAP kinase-responsive inhibitor of Ste12; regulates mating-specific genes and invasive growth in S. cerevisiae; induced by alpha pheromone in SpiderM medium || 1 0.80 0.70 0.27 0.14 0.09 -0.59 0.73 1.24 0.74 0.77 0.61 0.20 0.92 0.48 0.55 0.43
2192 || orf19.1738.1 || || || Protein involved in microtubule morphogenesis; required for protection from excess free beta-tubulin; possibly involved the beta-tubulin folding; Spider biofilm repressed || 1 2.24 2.29 0.16 0.55 0.07 -2.15 2.71 3.06 1.03 1.70 2.41 0.70 1.24 1.20 0.60 1.22
2193 || orf19.1738.1 || || || Protein involved in microtubule morphogenesis; required for protection from excess free beta-tubulin; possibly involved the beta-tubulin folding; Spider biofilm repressed || 1 1.98 2.20 0.40 0.95 -0.10 -1.96 2.39 3.12 1.32 1.85 2.47 0.82 1.59 1.84 0.77 1.37
2194 || orf19.4308 || HSL1 || || Probable protein kinase involved in determination of morphology during the cell cycle of both yeast-form and hyphal cells via regulation of Swe1p and Cdc28p; required for full virulence and kidney colonization in mouse systemic infection || 1 1.17 1.01 0.57 0.57 -0.25 -1.15 0.96 1.73 0.52 0.53 1.29 0.23 1.32 0.67 0.11 0.71
2195 || orf19.5008.1 || DAD1 || || Subunit of the Dam1 (DASH) complex, which acts in chromosome segregation by coupling kinetochores to spindle microtubules || 1 1.31 1.45 0.70 0.77 -0.61 -0.98 1.44 1.91 1.08 1.11 1.24 -0.18 1.19 1.30 0.08 0.35
2196 || orf19.7450 || || || Ortholog(s) have role in cytokinesis, septin ring assembly and cellular bud neck septin ring localization || 1 1.64 1.66 0.79 0.99 -0.43 -1.47 1.13 1.47 0.26 0.98 1.33 0.16 1.22 1.31 0.50 0.38
2197 || orf19.2612 || || || C2H2 zinc finger transcription factor; expression reduced in ssr1 null mutant; flow model biofilm induced || 1 0.70 0.87 0.60 0.34 -0.14 -0.56 0.71 0.85 0.44 0.16 0.67 0.04 0.58 0.38 0.36 0.16
2198 || orf19.4930 || SPC3 || || Essential protein; similar to S. cerevisiae Spc3p, a component of the signal peptidase complex required for signal peptidase activity; predicted integral ER membrane protein; complements spc3 and suppresses sec61 S. cerevisiae mutants || 1 0.64 0.54 0.44 0.38 -0.51 -1.16 0.63 1.20 0.12 0.62 1.10 0.18 0.59 0.87 0.49 0.23
2199 || orf19.5008.1 || DAD1 || || Subunit of the Dam1 (DASH) complex, which acts in chromosome segregation by coupling kinetochores to spindle microtubules || 1 0.88 0.76 0.17 0.02 -0.08 -0.73 0.56 1.20 0.09 0.39 1.73 0.43 0.99 0.90 0.67 0.83
2200 || orf19.779 || HAT1 || || Hat1-Hat2 histone acetyltransferase complex subunit; involved in DNA damage repair and morphogenesis; mutations cause constitutive pseudohyphal growth, white to opaque switch, caspofungin sensitivity; rat catheter, Spider biofilm repressed || 1 0.78 0.84 -0.22 0.14 -0.29 -0.47 0.61 1.15 0.63 1.17 1.95 0.98 0.12 0.71 0.23 1.16
2201 || orf19.2088 || || || Putative DNA polymerase epsilon subunit D; null mutant is viable but slow-growing and displays abnormal invasive growth on SD and YPD media; Spider biofilm repressed || 1 0.81 1.09 -0.14 0.51 0.48 -0.44 1.10 1.37 0.35 1.12 2.21 0.84 0.79 1.03 0.14 0.91
2202 || orf19.200 || || || Putative nuclear RNA-binding protein; Spider biofilm repressed || 1 0.61 0.41 -0.13 0.19 0.16 -0.34 0.56 1.00 0.18 0.59 1.44 0.86 0.63 1.16 0.55 1.01
2203 || orf19.2642 || || || Ortholog(s) have myosin II binding activity, role in actomyosin contractile ring contraction and cellular bud neck contractile ring localization || 1 0.09 0.35 -0.19 -0.04 -0.08 -0.36 0.60 0.82 0.58 0.44 1.69 1.07 0.59 1.00 0.58 0.75
2204 || orf19.2534 || PIN4 || || Protein with similarity to S. cerevisiae Pin4p; transposon mutation affects filamentous growth || 1 0.39 0.29 0.05 0.23 -0.34 -0.44 0.80 0.98 0.50 0.46 0.90 0.46 0.89 0.70 0.65 0.62
2205 || orf19.3225 || CWH43 || || Putative sensor/transporter protein with a predicted role in cell wall biogenesis; possibly an essential gene, disruptants not obtained by UAU1 method; flow model and rat catheter biofilm repressed || 1 0.26 0.20 0.19 0.29 -0.02 -0.63 0.92 1.10 0.57 0.65 0.86 0.42 0.63 0.67 0.35 0.42
2206 || orf19.1429 || SOH1 || || Subunit of the RNA polymerase II mediator complex; involved in control of cytokinesis, morphogenesis, biofilm formation, virulence; cell-cycle regulated periodic mRNA expression || 1 0.57 0.57 0.13 0.07 -0.14 -0.76 0.80 1.24 0.36 0.83 0.97 0.50 1.02 1.14 0.60 0.17
2207 || orf19.4837 || DAM1 || || Essential subunit of the Dam1 (DASH) complex, which acts in chromosome segregation by coupling kinetochores to spindle microtubules || 1 0.46 0.19 0.36 0.19 -0.30 -0.93 0.96 1.25 0.07 0.77 1.21 0.89 0.88 0.96 0.23 0.65
2208 || orf19.6294 || MYO1 || || Component of actomyosin ring at neck of newly-emerged bud || 1 0.94 0.38 -0.23 0.22 0.29 -1.38 1.18 2.11 0.52 1.66 1.82 1.21 0.92 1.57 0.86 1.00
2209 || orf19.3788 || SPC34 || || Subunit of the Dam1 (DASH) complex, which acts in chromosome segregation by coupling kinetochores to spindle microtubules || 1 0.65 0.79 0.27 0.41 -0.24 -1.13 0.69 0.99 0.21 0.82 1.03 0.60 0.37 1.07 0.19 0.84
2210 || orf19.3623 || SMC2 || || Protein similar to S. cerevisiae Smc2p, which is a component of the condensin complex involved in mitotic chromosome condensation; induced under hydroxyurea treatment || 1 0.76 0.87 0.10 0.16 -0.54 -1.51 0.83 0.99 0.85 1.10 1.36 0.71 0.84 1.58 0.10 0.90
2211 || orf19.779 || HAT1 || || Hat1-Hat2 histone acetyltransferase complex subunit; involved in DNA damage repair and morphogenesis; mutations cause constitutive pseudohyphal growth, white to opaque switch, caspofungin sensitivity; rat catheter, Spider biofilm repressed || 1 0.43 0.49 0.01 0.14 -0.50 -0.69 0.81 1.18 0.61 1.31 1.70 1.05 0.48 1.33 0.22 0.18
2212 || orf19.1420 || || || Ortholog(s) have cytosol, nucleus localization || 1 0.14 0.08 -0.06 0.04 -0.04 -0.70 0.48 0.73 0.50 0.64 0.70 0.21 0.13 0.75 0.26 0.23
2213 || orf19.1420 || || || Ortholog(s) have cytosol, nucleus localization || 1 0.20 0.02 0.22 -0.13 -0.19 -0.52 0.43 0.65 0.31 0.56 0.65 0.33 0.16 0.52 0.53 0.32
2214 || orf19.2739 || || || Ortholog(s) have histone binding activity, role in DNA replication-dependent nucleosome assembly and CAF-1 complex, chromosome, centromeric region, nucleus localization || 1 0.94 0.48 0.05 0.19 -0.21 -1.13 0.85 1.76 0.07 1.11 0.75 0.30 0.53 1.18 -0.16 0.54
2215 || orf19.1049 || || || Predicted NUDIX hydrolase domain; Hap43-induced || 1 0.48 0.99 0.04 0.64 -0.23 -0.59 0.41 0.79 -0.03 0.60 0.82 0.21 0.60 0.61 0.13 0.58
2216 || orf19.3843 || || || Ortholog(s) have role in filamentous growth, posttranslational protein targeting to membrane, translocation and Sec62/Sec63 complex localization || 1 0.51 0.63 0.19 0.43 -0.12 -0.68 0.58 1.08 0.28 0.76 0.73 0.53 0.24 0.41 0.32 -0.26
2217 || orf19.1448.1 || || || Ortholog(s) have plus-end-directed microtubule motor activity || 1 0.81 0.76 0.35 0.34 0.11 -0.28 1.01 1.51 0.38 0.58 1.29 0.46 0.50 0.99 0.04 -0.18
2218 || orf19.5938 || SEN1 || || Putative helicase; repressed by prostaglandins || 1 0.36 0.50 -0.03 0.38 -0.04 -0.33 0.67 0.77 0.16 0.55 0.84 -0.03 1.00 0.80 0.03 0.29
2219 || orf19.564 || KAR3 || || Kinesin-like microtubule motor protein; required for nuclear fusion during mating; C-terminal motor domain; mutants are viable; null has high-frequency white-opaque switching phenotype || 1 0.65 0.46 -0.15 -0.11 -0.01 -0.12 0.67 1.07 0.09 0.27 1.11 0.49 0.99 0.29 0.11 0.10
2220 || orf19.3248 || || || Ortholog of C. dubliniensis CD36 : Cd36_26070, C. parapsilosis CDC317 : CPAR2_803220, Candida tenuis NRRL Y-1498 : CANTEDRAFT_131795 and Debaryomyces hansenii CBS767 : DEHA2E12694g || 1 1.20 0.39 -0.05 -0.04 -0.34 -0.14 1.08 1.57 0.03 0.42 1.23 0.92 1.28 0.83 0.65 1.04
2221 || orf19.3730 || || || Protein similar to S. cerevisiae Kre27p, which has a role in resistance to killer toxin; predicted Kex2p substrate || 1 0.59 0.42 -0.08 0.14 0.08 -0.85 0.69 1.09 -0.22 0.35 1.20 0.24 0.61 0.04 0.46 0.28
2222 || orf19.4080 || || || Putative ribonuclease H2 subunit; required for RNase H2 activity; repressed in Spider biofilms by Bcr1, Tec1, Brg1, Rob1 || 1 0.48 0.40 -0.33 -0.05 -0.02 -1.43 1.03 0.75 0.44 0.80 1.26 0.35 0.77 0.48 -0.59 0.55
2223 || orf19.4437 || || || Ortholog(s) have ATPase activity, DNA binding, nucleosome binding, rDNA binding activity || 1 0.51 0.63 -0.24 -0.05 0.16 -1.00 0.73 1.34 0.10 0.35 1.38 0.41 0.65 0.38 -0.43 0.65
2224 || orf19.3762 || || || Ortholog of C. dubliniensis CD36 : Cd36_11720, C. parapsilosis CDC317 : CPAR2_201890, Candida tenuis NRRL Y-1498 : CANTEDRAFT_91948 and Debaryomyces hansenii CBS767 : DEHA2E16786g || 1 0.42 0.47 -0.59 -0.23 -0.07 -0.94 1.03 1.05 0.06 0.21 1.27 0.20 0.35 -0.05 0.09 0.65
2225 || orf19.7477 || YRB1 || || Functional homolog of S. cerevisiae Yrb1p; regulates Gsp1 GTPase activity and thereby affects nucleocytoplasmic transport and cytoskeletal dynamics; transcript is not regulated by white-opaque switch or by dimorphic transition || 1 0.17 0.22 -0.67 -0.56 -0.22 -0.60 1.08 1.32 0.16 1.09 1.38 0.60 0.78 0.51 0.03 0.67
2226 || orf19.7477 || YRB1 || || Functional homolog of S. cerevisiae Yrb1p; regulates Gsp1 GTPase activity and thereby affects nucleocytoplasmic transport and cytoskeletal dynamics; transcript is not regulated by white-opaque switch or by dimorphic transition || 1 0.38 0.56 -0.56 -0.14 0.02 -0.54 0.65 1.12 0.28 0.63 1.26 0.53 0.63 0.17 0.05 0.47
2227 || orf19.4796 || || || Putative eIF-4E-binding repressor of CAP-dependent translation; stationary phase enriched protein || 1 0.29 0.38 -0.55 -0.22 -0.01 -0.35 0.60 1.40 0.38 1.11 1.25 0.65 0.61 0.45 0.09 -0.20
2228 || orf19.7353 || || || Ortholog(s) have plus-end-directed microtubule motor activity, tubulin-dependent ATPase activity || 1 0.28 0.65 -0.01 0.52 -0.03 -0.47 0.44 0.79 0.30 0.56 0.73 0.78 0.38 0.26 0.14 0.42
2229 || orf19.7097 || || || Putative cytoplasmic RNA-binding protein; heterozygous null mutant exhibits hypersensitivity to parnafungin and cordycepin in C. albicans fitness test; Spider biofilm repressed || 1 0.40 0.36 0.28 0.51 0.07 -0.47 0.57 1.02 0.00 0.61 1.05 0.72 0.06 0.07 0.14 0.48
2230 || orf19.3474 || IPL1 || || Putative Aurora kinase; Hap43-induced; induced during planktonic growth; possibly an essential gene, disruptants not obtained by UAU1 method || 1 0.33 0.23 0.48 0.67 -0.17 -0.56 0.89 1.05 0.12 0.23 1.16 0.85 0.11 0.31 0.38 0.59
2231 || orf19.7290 || || || Ortholog(s) have RNA cap binding activity, role in deadenylation-dependent decapping of nuclear-transcribed mRNA and cytoplasmic mRNA processing body, cytosol, mRNA cap binding complex, nucleus localization || 1 0.56 0.43 -0.16 -0.04 -0.14 -0.40 0.47 0.86 -0.16 0.67 1.18 0.62 0.68 0.76 0.72 0.20
2232 || orf19.7041 || || || Putative pre-tRNA processing protein; heterozygous null mutant exhibits hypersensitivity to parnafungin and cordycepin in the C. albicans fitness test || 1 0.25 0.36 0.02 0.02 -0.00 -0.45 0.31 0.45 -0.05 0.74 0.62 0.42 0.52 0.65 0.53 -0.04
2233 || orf19.1747 || KIP2 || || Putative kinesin-related motor protein involved in mitotic spindle positioning; repressed by alpha pheromone in SpiderM medium; periodic mRNA expression, peak at cell-cycle G2/M phase || 1 0.91 1.08 -0.37 0.23 -1.69 -1.20 0.90 0.81 0.75 0.80 0.99 0.61 1.36 1.08 0.61 -0.01
2234 || orf19.2660 || EAF3 || || Subunit of the NuA4 histone acetyltransferase complex; rat catheter and Spider biofilm induced || 1 1.38 1.11 0.40 0.85 -0.07 -0.01 1.48 0.59 0.01 0.82 1.29 0.45 1.50 1.20 -0.02 0.69
2235 || orf19.7452 || || || Ortholog(s) have chromatin binding activity and role in DNA replication initiation, DNA unwinding involved in DNA replication, double-strand break repair via break-induced replication || 1 1.15 1.09 0.11 0.24 0.08 -0.22 1.10 0.16 -0.26 0.89 1.02 0.64 1.01 0.43 0.56 0.59
2236 || orf19.1768 || || || Ortholog of C. parapsilosis CDC317 : CPAR2_407480, C. dubliniensis CD36 : Cd36_24170, Candida orthopsilosis Co 90-125 : CORT_0C06830 and Spathaspora passalidarum NRRL Y-27907 : SPAPADRAFT_65786 || 1 0.36 0.46 -0.15 0.17 0.46 -0.93 0.87 1.01 0.73 0.45 0.65 0.51 0.63 0.06 0.23 0.08
2237 || orf19.1413 || YFH1 || || Frataxin; may be required for iron storage or delivery; role in oxidative stress resistance; transcript regulated by Nrg1, repressed if iron absent induced by macrophage interaction; Hap43-repressed gene || 1 0.01 -0.32 -0.27 -0.60 -0.13 -0.79 0.40 0.74 0.51 0.27 0.73 0.36 -0.02 0.18 0.14 0.05
2238 || orf19.6341 || || || Ortholog(s) have 5-amino-6-(5-phosphoribosylamino)uracil reductase activity, role in riboflavin biosynthetic process and cytosol, nucleus localization || 1 0.18 0.37 -0.34 0.01 -0.13 -1.01 0.40 0.69 0.01 0.45 0.23 0.19 0.06 0.69 0.44 0.31
2239 || orf19.7391 || OCH1 || || Alpha-1,6-mannosyltransferase; initiates N-glycan outer chain branch addition; similar to S. cerevisiae Och1p; required for wild-type virulence in mouse intravenous infection; fungal-specific (no human or murine homolog) || 1 0.11 0.16 -0.54 -0.22 -0.67 -1.07 0.73 0.98 0.16 0.37 0.40 0.24 0.63 1.03 0.64 -0.01
2240 || orf19.7345 || || || Ortholog(s) have ATP binding activity and cytosol, nucleus localization || 1 -0.08 0.03 -0.35 -0.46 0.24 -0.68 0.52 0.32 0.04 0.47 0.50 0.48 0.69 0.51 0.65 -0.13
2241 || orf19.4755 || KEX2 || || Subtilisin-like protease (proprotein convertase); processes aspartyl proteinase Sap2; required for hyphal growth and wild-type virulence in mice; functional homolog of S. cerevisiae Kex2, which processes alpha-factor; Tup1-repressed || 1 0.07 0.02 -0.47 -0.08 0.05 -0.70 0.73 0.86 0.33 0.90 0.75 0.43 0.63 0.65 0.58 -0.00
2242 || orf19.4656 || || || Ortholog of C. dubliniensis CD36 : Cd36_41300, C. parapsilosis CDC317 : CPAR2_400390, Candida tenuis NRRL Y-1498 : CANTEDRAFT_94704 and Debaryomyces hansenii CBS767 : DEHA2B02992g || 1 0.13 0.09 -0.58 -0.47 -0.19 -1.17 0.57 0.72 0.31 0.85 0.69 0.63 0.44 0.60 0.80 -0.04
2243 || orf19.1835 || PEA2 || || Putative coiled-coil polarisome; predicted role in polarized morphogenesis, cell fusion, and low affinity Ca2+ influx; rat catheter biofilm induced || 1 0.06 0.16 -0.77 -0.41 -0.02 -1.54 1.55 0.71 0.46 1.01 1.08 1.11 1.16 0.47 0.63 -0.00
2244 || orf19.1835 || PEA2 || || Putative coiled-coil polarisome; predicted role in polarized morphogenesis, cell fusion, and low affinity Ca2+ influx; rat catheter biofilm induced || 1 0.28 0.36 -0.64 -0.29 0.22 -1.28 0.69 0.45 0.60 1.06 0.65 0.83 0.93 0.32 0.21 -0.10
2245 || orf19.1334 || || || Protein of unknown function; repressed by alpha pheromone in SpiderM medium || 1 0.15 0.15 -1.03 -0.84 -0.27 -1.48 1.37 0.74 0.51 1.06 0.81 0.02 1.20 0.88 0.23 0.47
2246 || orf19.7489.3 || || || Ortholog(s) have role in negative regulation of transcription from RNA polymerase II promoter in response to iron and cytosol, nucleus localization || 1 -0.50 -0.25 -0.51 -0.47 -0.48 -1.05 0.49 0.69 0.41 0.80 1.10 0.32 0.81 0.60 0.13 0.16
2247 || orf19.4236 || RET2 || || Delta subunit of the coatomer complex (COPI); coats Golgi-derived transport vesicles; involved in retrograde transport between Golgi and ER; interacts with Crk1 in the two-hybrid system; Spider biofilm repressed || 1 -0.09 -0.14 -0.11 -0.31 -0.39 -0.71 0.19 0.55 0.09 0.26 0.66 0.24 -0.00 0.05 0.12 0.51
2248 || orf19.836 || || || Protein likely to be essential for growth, based on an insertional mutagenesis strategy || 1 0.02 0.20 -0.74 -0.76 -0.38 -1.68 0.70 1.08 0.01 0.25 0.98 0.62 0.26 0.32 0.15 0.93
2249 || orf19.2664 || || || Ortholog(s) have role in cellular response to DNA damage stimulus, interspecies interaction between organisms and cytosol, nucleus, polysome localization || 1 0.09 0.00 -0.65 -0.66 -0.76 -1.12 0.57 0.63 -0.05 0.15 0.84 0.47 0.25 0.27 0.29 0.82
2250 || orf19.528 || SEC26 || || Secretory vesicles coatomer complex protein || 1 -0.25 -0.12 -0.47 -0.63 -0.61 -0.94 0.62 0.59 0.06 0.23 0.78 0.41 0.17 0.26 -0.13 0.83
2251 || orf19.6242 || CYK3 || || Essential protein involved in cytokinesis; contains an SH3 domain || 1 -0.18 -0.28 -0.76 -0.59 -0.57 -1.02 0.61 0.77 0.16 0.03 1.20 0.43 0.29 0.21 -0.04 0.72
2252 || orf19.2983 || CDC73 || || Putative transcription elongation factor; cdc73 kap114 double transposon mutation affects filamentous growth; Spider biofilm repressed || 1 -0.39 -0.35 -0.59 -0.67 -0.39 -0.81 0.67 0.76 0.26 0.16 1.14 0.71 0.45 0.48 0.19 0.97
2253 || orf19.6242 || CYK3 || || Essential protein involved in cytokinesis; contains an SH3 domain || 1 -0.21 -0.31 -0.48 -0.36 -0.94 -0.90 0.75 0.94 0.17 0.11 1.32 0.68 0.52 0.33 -0.09 0.58
2254 || orf19.20 || RTS1 || || Putative serine/threonine-protein phosphatase B-type regulatory subunit; transcription is regulated upon yeast-hyphal switch || 1 0.05 0.08 -0.43 -0.29 -0.51 -0.95 0.83 1.18 0.50 0.41 1.14 0.51 0.73 0.27 0.17 0.61
2255 || orf19.5595 || SHE3 || || mRNA-binding protein that localizes specific mRNAs to daughter yeast cells and to hyphal tips; required for normal filamentation and host epithelial cell damage; ortholog of S. cerevisiae She3 but target mRNAs differs || 1 0.58 0.54 -1.12 -0.43 -0.85 -1.80 2.11 2.30 0.79 1.38 1.82 0.24 1.51 0.78 1.03 0.54
2256 || orf19.5964.2 || RPL35 || || Ribosomal protein; downregulation correlates with clinical development of fluconazole resistance; colony morphology-related gene regulation by Ssn6; Hap43-induced; Spider biofilm repressed || 1 1.16 1.42 -1.25 -0.50 -1.08 -2.79 3.71 3.95 1.20 1.53 3.95 1.35 2.44 1.26 1.52 1.03
2257 || orf19.5964.2 || RPL35 || || Ribosomal protein; downregulation correlates with clinical development of fluconazole resistance; colony morphology-related gene regulation by Ssn6; Hap43-induced; Spider biofilm repressed || 1 1.24 1.14 -1.70 -1.23 -1.02 -2.80 3.66 3.82 0.98 1.29 4.05 1.31 2.40 1.18 1.81 1.35
2258 || orf19.2111.2 || RPL38 || || 60S ribosomal ribosomal protein subunit; genes encoding cytoplasmic ribosomal subunits, translation factors, tRNA synthetases are downregulated upon phagocytosis by murine macrophage || 1 1.07 0.93 -1.32 -1.13 -0.79 -2.52 3.34 3.34 0.58 0.97 3.35 0.57 1.84 0.71 1.37 0.80
2259 || orf19.2310.1 || RPL29 || || Ribosomal protein L29; induced upon germ tube formation; colony morphology-related gene regulation by Ssn6; intron in 5'-UTR; Spider biofilm repressed || 1 0.56 0.64 -1.79 -1.16 -1.49 -2.87 3.21 3.20 0.87 1.37 3.23 1.12 1.75 1.02 1.52 0.96
2260 || orf19.4375.1 || RPS30 || || Putative 40S ribosomal protein S30; colony morphology-related gene regulation by Ssn6; rat catheter biofilm repressed || 1 0.37 0.27 -1.29 -0.61 -1.20 -2.24 2.28 2.54 0.57 0.95 2.49 0.96 1.30 0.64 0.88 0.71
2261 || orf19.827.1 || RPL39 || || Ribosomal protein L39; transcript induced upon germ tube formation; colony morphology-related gene regulation by Ssn6; Hap43-induced || 1 0.26 0.37 -1.18 -0.75 -0.83 -2.32 2.43 2.63 0.93 1.09 2.98 1.09 1.34 0.98 0.91 1.00
2262 || orf19.2310.1 || RPL29 || || Ribosomal protein L29; induced upon germ tube formation; colony morphology-related gene regulation by Ssn6; intron in 5'-UTR; Spider biofilm repressed || 1 0.76 0.76 -1.79 -1.58 -1.17 -3.10 3.02 3.26 0.77 1.32 3.19 0.59 2.04 0.78 1.31 0.69
2263 || orf19.2111.2 || RPL38 || || 60S ribosomal ribosomal protein subunit; genes encoding cytoplasmic ribosomal subunits, translation factors, tRNA synthetases are downregulated upon phagocytosis by murine macrophage || 1 0.77 0.85 -2.04 -1.69 -1.19 -3.13 3.33 3.26 0.45 1.06 3.46 0.70 1.99 0.62 1.35 0.87
2264 || orf19.2111.2 || RPL38 || || 60S ribosomal ribosomal protein subunit; genes encoding cytoplasmic ribosomal subunits, translation factors, tRNA synthetases are downregulated upon phagocytosis by murine macrophage || 1 0.67 0.85 -2.10 -1.65 -0.94 -3.44 3.35 3.32 0.34 1.04 3.56 0.91 2.04 0.82 1.50 0.79
2265 || orf19.2111.2 || RPL38 || || 60S ribosomal ribosomal protein subunit; genes encoding cytoplasmic ribosomal subunits, translation factors, tRNA synthetases are downregulated upon phagocytosis by murine macrophage || 1 0.53 0.54 -2.11 -1.63 -0.97 -3.25 3.23 3.11 0.46 0.94 3.31 0.48 1.96 0.75 1.28 0.71
2266 || orf19.2111.2 || RPL38 || || 60S ribosomal ribosomal protein subunit; genes encoding cytoplasmic ribosomal subunits, translation factors, tRNA synthetases are downregulated upon phagocytosis by murine macrophage || 1 0.54 0.78 -2.28 -1.62 -1.30 -3.52 3.41 3.21 0.53 1.12 3.41 0.63 1.81 0.92 1.31 0.66
2267 || orf19.20 || RTS1 || || Putative serine/threonine-protein phosphatase B-type regulatory subunit; transcription is regulated upon yeast-hyphal switch || 1 0.44 0.28 -0.49 -0.35 -0.44 -0.97 0.94 1.04 0.09 0.43 1.15 0.44 0.51 0.87 0.28 0.52
2268 || orf19.514 || SNP3 || || Putative U6 snRNA-associated protein; transcript regulated by Mig1 || 1 0.25 0.19 -0.56 -0.23 -0.63 -1.23 1.17 1.61 0.22 0.88 2.07 0.78 0.79 0.75 0.45 0.14
2269 || orf19.4193 || || || Ortholog(s) have Arp2/3 complex binding activity, role in actin cortical patch assembly, actin filament debranching, negative regulation of Arp2/3 complex-mediated actin nucleation and actin cortical patch, cytosol, nucleus localization || 1 0.25 0.02 -0.65 -0.06 -0.26 -0.93 0.50 1.23 0.19 0.68 1.44 0.53 0.29 0.63 0.34 0.33
2270 || orf19.7234 || || || Putative RSC chromatin remodeling complex component; possibly an essential gene, disruptants not obtained by UAU1 method || 1 0.07 -0.11 -0.80 -0.52 -0.13 -1.01 0.80 1.05 -0.06 0.43 1.50 0.66 0.53 0.25 0.48 0.37
2271 || orf19.5518 || || || Protein of unknown function; Spider biofilm induced || 1 0.33 0.00 -0.93 -0.67 0.18 -1.08 0.96 1.53 0.12 0.46 1.50 0.61 0.43 0.23 0.32 0.36
2272 || orf19.5516 || || || Ortholog(s) have signal sequence binding activity, role in protein targeting to ER and cytosol, nucleus, signal recognition particle, endoplasmic reticulum targeting localization || 1 -0.32 -0.28 -1.11 -0.93 -0.71 -1.59 0.73 1.07 0.22 0.55 1.09 0.18 0.11 0.29 -0.06 0.10
2273 || orf19.3788.1 || RPL30 || || Ribosomal 60S subunit protein; pre-rRNA processing; pre-mRNA alternatively spliced to productive/unproductive transcripts; temp-regulated splicing; colony morphology-related regulation by Ssn6, Tup1, Nrg1 regulated; Spider biofilm repressed || 1 -0.57 -0.33 -2.17 -1.10 -1.54 -3.56 1.60 1.98 0.61 0.96 1.93 0.69 0.80 0.04 0.05 0.23
2274 || orf19.4375.1 || RPS30 || || Putative 40S ribosomal protein S30; colony morphology-related gene regulation by Ssn6; rat catheter biofilm repressed || 1 -0.28 -0.22 -2.58 -1.56 -1.65 -2.97 1.73 1.61 0.10 0.60 1.72 0.09 0.94 -0.22 0.48 0.09
2275 || orf19.7048.1 || RPS28B || || Putative ribosomal protein S28B || 1 -0.37 -0.35 -2.36 -1.55 -1.89 -3.84 2.02 2.00 -0.31 0.39 2.28 0.27 0.86 -0.01 0.54 -0.00
2276 || orf19.4909.1 || RPL42 || || Putative 60S ribosomal subunit protein; colony morphology-related gene regulation by Ssn6; Spider biofilm repressed || 1 -0.20 -0.23 -2.28 -1.87 -2.85 -4.34 2.40 2.52 0.05 0.28 2.45 0.29 1.03 0.56 0.54 0.28
2277 || orf19.4909.1 || RPL42 || || Putative 60S ribosomal subunit protein; colony morphology-related gene regulation by Ssn6; Spider biofilm repressed || 1 -0.20 -0.14 -2.36 -1.73 -2.63 -4.20 2.59 2.74 0.32 0.49 2.74 0.26 1.19 0.68 0.90 0.25
2278 || orf19.6264.4 || || || Ortholog of S. cerevisiae Rpl39; a component of the 60S ribosomal subunit; Hap43-induced; Spider biofilm repressed || 1 -0.35 -0.11 -2.41 -1.91 -1.75 -3.21 2.26 2.31 0.00 0.65 2.60 0.68 0.95 0.75 0.58 0.60
2279 || orf19.5445 || GLO3 || || Putative ARF GTPase activator; role in COPI coating of Golgi vesicle, ER to Golgi vesicle-mediated transport, retrograde Golgi to ER vesicle-mediated transport; Spider biofilm repressed || 1 0.07 0.05 -0.50 -0.38 -0.41 -0.89 0.68 0.80 0.18 0.34 0.74 0.41 0.17 0.38 0.22 0.31
2280 || orf19.7018 || RPS18 || || Predicted ribosomal protein; repressed upon phagocytosis by murine macrophage; repressed by nitric oxide; Hap43-induced; Spider biofilm repressed || 1 -0.42 -0.35 -1.62 -1.04 -1.99 -3.26 1.87 2.16 0.86 0.93 2.26 0.95 0.76 0.92 0.53 0.84
2281 || orf19.7048.1 || RPS28B || || Putative ribosomal protein S28B || 1 -0.17 -0.20 -1.75 -0.89 -1.93 -3.06 2.03 2.06 0.46 1.00 2.23 0.97 1.03 0.81 0.55 0.50
2282 || orf19.3572.3 || || || Ribosomal 60S subunit protein L31B; Spider biofilm repressed || 1 0.01 0.01 -1.68 -1.45 -1.89 -3.09 2.13 2.19 0.53 0.82 2.49 0.73 1.04 0.75 0.44 0.63
2283 || orf19.7018 || RPS18 || || Predicted ribosomal protein; repressed upon phagocytosis by murine macrophage; repressed by nitric oxide; Hap43-induced; Spider biofilm repressed || 1 -0.19 -0.25 -2.15 -1.63 -2.53 -3.58 2.29 2.55 0.38 0.92 2.50 0.79 0.80 0.82 0.43 0.80
2284 || orf19.687.1 || RPL25 || || Putative rRNA-binding ribosomal protein component of the 60S ribosomal subunit; Hap43-induced; colony morphology-related gene regulation by Ssn6 || 1 0.19 0.11 -1.74 -1.07 -2.34 -3.45 2.22 2.43 0.56 0.80 2.66 0.45 1.06 0.38 0.49 0.57
2285 || orf19.4909.1 || RPL42 || || Putative 60S ribosomal subunit protein; colony morphology-related gene regulation by Ssn6; Spider biofilm repressed || 1 0.34 0.13 -1.77 -1.08 -2.66 -3.97 2.69 3.01 0.72 0.87 2.98 0.72 1.22 0.87 0.86 0.49
2286 || orf19.827.1 || RPL39 || || Ribosomal protein L39; transcript induced upon germ tube formation; colony morphology-related gene regulation by Ssn6; Hap43-induced || 1 -0.02 0.03 -2.18 -1.27 -1.66 -3.09 2.40 2.58 0.56 0.81 2.79 1.01 0.61 1.06 0.62
2287 || orf19.3572.3 || || || Ribosomal 60S subunit protein L31B; Spider biofilm repressed || 1 -0.11 0.07 -1.84 -1.11 -1.60 -2.67 2.33 2.53 0.71 1.02 2.63 0.86 1.17 1.28 0.92 0.97
2288 || orf19.4909.1 || RPL42 || || Putative 60S ribosomal subunit protein; colony morphology-related gene regulation by Ssn6; Spider biofilm repressed || 1 0.25 0.35 -1.50 -0.90 -2.20 -3.58 2.70 3.16 0.90 1.17 3.12 0.90 1.64 1.16 0.78 0.85
2289 || orf19.4909.1 || RPL42 || || Putative 60S ribosomal subunit protein; colony morphology-related gene regulation by Ssn6; Spider biofilm repressed || 1 0.28 0.32 -1.50 -0.72 -2.28 -3.67 2.70 3.10 1.24 1.00 3.31 1.06 1.62 1.06 0.86 0.57
2290 || orf19.1470 || RPS26A || || Ribosomal protein; regulated by Nrg1, Tup1; repressed upon phagocytosis by murine macrophage; alternatively spliced intron in 5'-UTR; Spider biofilm repressed || 1 0.41 0.46 -1.25 -0.48 -3.03 -3.81 3.20 3.14 1.42 2.77 0.94 1.73 0.76 1.01 0.63
2291 || orf19.4560 || BFR1 || || Protein involved in the maintenance of normal ploidy; S. cerevisiae ortholog cofers Brefeldin A resistance; stationary phase enriched protein; Spider biofilm repressed || 1 0.16 0.16 -0.79 -0.54 -1.30 -1.87 1.39 1.52 0.20 0.76 1.39 0.16 0.62 0.48 -0.23 0.11
2292 || orf19.4560 || BFR1 || || Protein involved in the maintenance of normal ploidy; S. cerevisiae ortholog cofers Brefeldin A resistance; stationary phase enriched protein; Spider biofilm repressed || 1 0.08 0.21 -0.87 -0.95 -1.05 -2.06 1.32 1.30 -0.04 0.65 1.05 -0.22 0.63 0.18 -0.23 0.05
2293 || orf19.3680 || SEP7 || || Septin, required for wild-type invasive growth in vitro but not required for virulence in a mouse model of systemic infection; localizes to hyphal septum or bud neck; Asn-rich; aberrant gel mobility; phosphorylated in vitro by Gin4p || 1 0.16 0.37 -0.91 -0.49 -0.74 -1.89 0.81 0.94 0.02 0.64 1.17 -0.33 0.71 0.43 -0.05 0.01
2294 || orf19.2964 || || || Ortholog(s) have DNA translocase activity || 1 0.16 0.19 -0.25 -0.38 -0.29 -0.90 0.49 0.76 -0.16 0.07 0.74 0.12 0.49 0.27 0.06 0.22
2295 || orf19.2964 || || || Ortholog(s) have DNA translocase activity || 1 -0.08 0.27 -0.69 -0.69 -0.12 -1.13 0.71 0.95 -0.19 -0.04 0.90 0.10 0.76 0.44 0.09 0.12
2296 || orf19.3683 || AGE3 || || Putative ADP-ribosylation factor GTPase activating protein, functional ortholog of S. cerevisiae GCS1; mutation affects endocytosis, hyphal growth, chemical and drug resistance, and sensitivity to cell wall inhibitors || 1 0.29 0.37 -0.86 -0.92 -0.37 -1.40 0.57 0.96 -0.05 0.12 1.27 -0.08 0.60 0.10 0.26 -0.04
2297 || orf19.2664 || || || Ortholog(s) have role in cellular response to DNA damage stimulus, interspecies interaction between organisms and cytosol, nucleus, polysome localization || 1 0.12 0.22 -0.63 -0.84 -0.40 -1.18 0.49 0.57 0.04 -0.09 0.92 0.12 0.23 0.08 0.11 0.36
2298 || orf19.2763 || || || Protein not essential for viability; orf19.10279 possibly transcriptionally regulated upon hyphal formation || 1 0.17 -0.01 -1.12 -1.44 -0.77 -1.38 0.54 1.15 0.19 0.02 1.74 0.56 1.02 0.63 0.09 0.51
2299 || orf19.6010.1 || RPB11 || || Putative RNA polymerase II subunit; flucytosine induced || 1 0.16 0.13 -0.46 -0.49 -0.64 -0.89 0.43 0.99 -0.10 0.19 1.03 0.20 0.31 0.44 0.47 -0.29
2300 || orf19.6424 || || || Ortholog(s) have SUMO ligase activity and role in cellular response to DNA damage stimulus, hyphal growth, mitotic spindle elongation, protein sumoylation, regulation of mitotic cell cycle || 1 -0.00 0.20 -0.69 -0.58 -0.15 -0.57 0.79 0.99 0.02 0.06 1.27 0.35 0.26 0.25 -0.10 0.12
2301 || orf19.4068 || || || Protein of unknown function; flow model biofilm induced || 1 0.23 -0.03 -1.10 -0.77 -0.53 -1.34 0.40 1.14 -0.07 -0.13 1.44 0.36 0.20 -0.15 0.39 0.54
2302 || orf19.3349 || || || Putative RNA polymerase II subunit B150; heterozygous null mutant exhibits resistance to parnafungin in the C. albicans fitness test || 1 -0.18 -0.31 -0.97 -0.70 -0.08 -0.99 0.82 0.93 0.28 0.24 0.62 -0.21 0.30 0.21 0.25 0.25
2303 || orf19.2920 || || || Ortholog(s) have role in ribosome biogenesis and cytosol, ribosome localization || 1 0.03 -0.11 -0.38 -0.35 -0.05 -0.51 0.39 0.76 -0.25 0.34 0.97 -0.01 0.20 0.20 0.16 -0.22
2304 || orf19.3063 || HFL1 || || HAP5-like; ortholog of S. cerevisiae Dpb3; third-largest subunit of DNA polymerase II (DNA polymerase epsilon); phosphorylated protein; mutants have a growth defect || 1 -0.01 -0.10 -0.35 -0.22 -0.09 -0.90 0.54 0.90 -0.06 0.69 0.76 0.16 0.23 0.23 -0.32 -0.26
2305 || orf19.1536 || || || Putative vacuolar transporter; Hap43-induced; required for normal filamentous growth; mRNA binds She3 and is localized to hyphal tips || 1 0.09 -0.09 -0.33 -0.10 -0.93 -1.08 0.14 0.49 -0.06 0.59 0.51 0.74 0.87 0.28 0.05 0.22
2306 || orf19.1536 || || || Putative vacuolar transporter; Hap43-induced; required for normal filamentous growth; mRNA binds She3 and is localized to hyphal tips || 1 0.22 0.37 -0.34 -0.13 -0.64 -0.96 0.16 0.56 -0.18 0.65 0.69 0.77 1.16 0.65 0.07 0.10
2307 || orf19.389 || || || Protein of unknown function; Hap43-induced gene || 1 0.12 0.35 0.01 -0.04 -1.04 -1.59 0.51 1.31 -0.40 1.10 1.07 0.66 0.77 0.90 -0.03 -0.36
2308 || orf19.3964 || ASH2 || || Ortholog(s) have histone methyltransferase activity (H3-K4 specific) activity || 1 -0.25 -0.05 -0.11 0.01 -0.41 -1.09 0.25 1.03 -0.10 0.63 0.93 0.39 1.12 0.66 -0.04 -0.28
2309 || orf19.1834 || || || Ortholog of C. dubliniensis CD36 : Cd36_09960, C. parapsilosis CDC317 : CPAR2_212580, Debaryomyces hansenii CBS767 : DEHA2G11770g and Pichia stipitis Pignal : PICST_51041 || 1 -0.00 0.01 -0.30 0.04 -0.04 -1.09 0.01 0.50 -0.11 0.53 0.66 0.32 0.53 0.38 -0.61 0.46
2310 || orf19.3715 || ASF1 || || Protein similar to S. cerevisiae Asf1p, a chromatin assembly complex component; likely to be essential for growth, based on an insertional mutagenesis strategy || 1 -0.19 -0.09 0.02 0.53 -0.67 -1.87 0.31 0.94 0.24 1.32 1.40 0.82 0.36 1.03 -0.87 0.80
2311 || orf19.1445 || ESC4 || || Protein similar to S. cerevisiae Esc4; a protein that represses transposition; transposon mutation affects filamentation; rat catheter biofilm repressed || 1 0.40 0.13 -0.20 0.08 -0.31 -1.33 0.37 0.72 -0.33 0.76 1.45 0.58 0.39 0.65 -0.40 0.08
2312 || orf19.4545 || SWI4 || || Putative component of the SBF transcription complex involved in G1/S cell-cycle progression; periodic mRNA expression, peak at cell-cycle G1/S phase; predicted, conserved MBF binding sites upstream of G1/S-regulated genes || 1 0.06 -0.05 -0.07 0.19 0.00 -1.16 0.32 1.00 -0.51 0.59 1.85 0.64 0.53 0.58 -0.04 0.48
2313 || orf19.4545 || SWI4 || || Putative component of the SBF transcription complex involved in G1/S cell-cycle progression; periodic mRNA expression, peak at cell-cycle G1/S phase; predicted, conserved MBF binding sites upstream of G1/S-regulated genes || 1 -0.30 -0.21 -0.20 -0.00 -0.23 -0.96 0.10 0.75 -0.57 0.58 1.44 0.73 0.12 0.57 -0.25 0.65
2314 || orf19.6843 || || || Ortholog(s) have role in CENP-A containing nucleosome assembly at centromere, chromatin silencing at centromere, mitotic sister chromatid segregation and nucleoplasm localization || 1 0.08 0.17 -0.38 -0.18 -0.26 -1.14 0.58 1.16 -0.31 0.71 1.41 0.60 -0.12 1.00 -0.39 0.90
2315 || orf19.4301 || || || Ortholog(s) have role in chromatin silencing at rDNA, chromatin silencing at silent mating-type cassette, chromatin silencing at telomere, regulation of transcription from RNA polymerase II promoter and nucleus localization || 1 0.29 0.24 -0.33 -0.17 -0.46 -1.16 0.03 1.03 -0.20 0.56 1.31 0.63 0.50 0.68 -0.36 1.07
2316 || orf19.514 || SNP3 || || Putative U6 snRNA-associated protein; transcript regulated by Mig1 || 1 -0.09 -0.04 -0.12 -0.11 -0.73 -1.26 0.67 1.73 0.28 0.48 1.36 0.67 0.36 0.79 0.13 0.47
2317 || orf19.668 || TOS4 || || Putative fork-head transcription factor; rat catheter and Spider biofilm repressed || 1 0.29 0.05 -0.46 -0.47 -0.89 -1.92 0.59 1.39 0.08 0.63 0.93 0.12 0.39 0.87 0.01 1.15
2318 || orf19.712 || KIP1 || || Non-essential kinesin from the bipolar (Kinesis-5) family; involved in formation of the mitotic spindle || 1 0.00 0.08 -0.34 -0.20 -1.08 -1.36 0.45 0.99 -0.06 0.44 0.83 0.54 0.72 1.12 -0.36 0.70
2319 || orf19.4301 || || || Ortholog(s) have role in chromatin silencing at rDNA, chromatin silencing at silent mating-type cassette, chromatin silencing at telomere, regulation of transcription from RNA polymerase II promoter and nucleus localization || 1 0.41 0.06 -0.44 -0.09 -1.38 -1.36 0.92 1.31 0.01 0.98 1.50 0.30 0.63 1.03 -0.79 0.57
2320 || orf19.2739 || || || Ortholog(s) have histone binding activity, role in DNA replication-dependent nucleosome assembly and CAF-1 complex, chromosome, centromeric region, nucleus localization || 1 0.25 0.35 -0.22 0.01 -0.71 -1.37 0.70 1.42 0.04 0.93 1.38 0.17 0.24 0.66 -0.44 0.24
2321 || orf19.2873 || TOP2 || || DNA topoisomerase II; catalyzes ATP-dependent DNA relaxation and decatenation in vitro; Y842 predicted to be catalytic; functional homolog of S. cerevisiae Top2p; sensitive to amsacrine or doxorubicin; farnesol-upregulated in biofilm || 1 0.63 0.94 -0.11 0.16 -1.09 -1.93 1.24 1.92 0.05 0.79 1.80 0.54 0.54 1.14 -0.11 0.99
2322 || orf19.2873 || TOP2 || || DNA topoisomerase II; catalyzes ATP-dependent DNA relaxation and decatenation in vitro; Y842 predicted to be catalytic; functional homolog of S. cerevisiae Top2p; sensitive to amsacrine or doxorubicin; farnesol-upregulated in biofilm || 1 0.45 0.57 0.02 0.16 -1.15 -1.83 0.91 1.48 0.15 0.77 1.48 0.85 0.43 1.11 -0.54 0.84
2323 || orf19.3623 || SMC2 || || Protein similar to S. cerevisiae Smc2p, which is a component of the condensin complex involved in mitotic chromosome condensation; induced under hydroxyurea treatment || 1 0.72 0.61 0.08 0.39 -0.78 -1.57 0.34 1.00 0.25 0.46 1.31 0.64 0.18 0.74 -0.41 0.53
2324 || orf19.175 || || || Ortholog of C. dubliniensis CD36 : Cd36_27430, C. parapsilosis CDC317 : CPAR2_802450, Candida tenuis NRRL Y-1498 : CANTEDRAFT_113969 and Debaryomyces hansenii CBS767 : DEHA2A13002g || 1 0.30 0.24 -0.05 0.15 -0.65 -1.78 0.41 1.06 0.36 0.42 0.62 0.76 0.46 0.56 -0.28 0.40
2325 || orf19.4703 || || || Protein with similarity to mutator-like element (MULE) transposase || 1 0.13 0.09 -0.17 -0.24 -0.43 -0.79 0.43 0.65 0.24 0.06 0.74 0.59 0.20 0.49 -0.47 0.85
2326 || orf19.3296 || || || Ortholog of C. dubliniensis CD36 : Cd36_01020, C. parapsilosis CDC317 : CPAR2_110130, Candida tenuis NRRL Y-1498 : CANTEDRAFT_93515 and Debaryomyces hansenii CBS767 : DEHA2D14542g || 1 0.04 0.07 -0.30 0.14 -0.48 -1.00 0.88 0.59 0.19 0.17 0.99 0.06 0.50 1.13 -0.18 1.30
2327 || orf19.2615 || MDL1 || || Putative mitochondrial, half-size MDR-subfamily ABC transporter || 1 0.19 0.23 0.10 0.25 -0.45 -0.76 0.23 0.54 0.01 0.22 0.44 0.17 0.20 0.51 0.12 0.82
2328 || orf19.836 || || || Protein likely to be essential for growth, based on an insertional mutagenesis strategy || 1 -0.12 0.03 -0.31 -0.29 -0.29 -1.18 0.32 0.64 -0.11 -0.21 1.00 0.40 0.25 0.81 -0.03 0.61
2329 || orf19.5938 || SEN1 || || Putative helicase; repressed by prostaglandins || 1 0.07 0.10 -0.38 0.12 -0.09 -0.59 0.38 0.68 -0.12 0.59 0.80 0.13 0.60 0.67 0.18 0.55
2330 || orf19.2200 || || || Protein of unknown function; rat catheter biofilm repressed || 1 0.17 0.05 -0.24 -0.02 -0.24 -0.54 0.37 0.50 0.06 0.38 0.57 0.42 -0.15 0.65 0.10 0.07
2331 || orf19.5378 || SCL1 || || Proteasome subunit YC7alpha; protein present in exponential and stationary growth phase yeast cultures; flow model and Spider biofilm repressed || 1 0.45 0.23 -0.21 0.18 -0.43 -0.59 0.32 0.71 0.11 0.41 0.78 0.57 -0.25 0.37 0.37 0.52
2332 || orf19.4061 || || || Protein of unknown function; clade-associated gene expression || 1 0.42 0.44 -0.66 0.27 -0.12 -0.70 0.35 1.25 -0.15 0.58 0.74 0.45 0.31 0.43 0.05 1.17
2333 || orf19.485 || || || Ortholog(s) have structural constituent of cytoskeleton activity || 1 0.29 0.09 -0.14 0.08 0.03 -0.51 0.02 0.42 -0.16 0.23 0.40 0.15 0.04 0.25 -0.10 0.38
2334 || orf19.389 || || || Protein of unknown function; Hap43-induced gene || 1 0.52 0.76 -0.32 -0.25 0.03 -1.90 0.93 1.20 -0.23 0.69 1.26 0.72 1.06 0.05 0.13 -0.43
2335 || orf19.2328 || || || Ortholog of C. dubliniensis CD36 : Cd36_10220, C. parapsilosis CDC317 : CPAR2_210530, Candida tenuis NRRL Y-1498 : CANTEDRAFT_105553 and Debaryomyces hansenii CBS767 : DEHA2G14432g || 1 0.40 0.33 0.04 -0.14 -0.17 -0.95 0.08 0.39 0.00 0.19 0.34 0.12 0.28 0.05 -0.05 0.22
2336 || orf19.3494 || CTF5 || || Predicted component of the kinetochore sub-complex COMA; induced during the mating process; repressed by alpha pheromone in SpiderM medium || 1 0.88 0.95 -0.51 -0.56 -0.40 -2.43 1.18 1.14 -0.07 0.59 0.28 0.19 0.78 0.30 -0.41 0.22
2337 || orf19.5929 || || || Putative protein of unknown function, transcription is positively regulated by Tbf1p || 1 0.15 0.40 -0.18 -0.38 -0.13 -1.59 0.76 0.34 -0.13 0.12 0.33 -0.25 0.68 0.33 -0.02 0.43
2338 || orf19.3631 || STN1 || || Protein involved in telomere maintenance; forms a complex with Ten1p || 1 0.30 0.40 -0.62 0.05 -0.88 -3.33 1.12 0.79 -0.22 0.06 0.93 0.86 0.83 0.49 0.61 0.90
2339 || orf19.5242 || CDC6 || || Putative ATP-binding protein with a predicted role in DNA replication; member of conserved Mcm1p regulon; periodic mRNA expression, peak at cell-cycle M/G1 phase || 1 -0.37 0.05 -0.78 -0.93 -0.10 -5.54 0.75 0.80 -0.04 0.87 0.98 1.07 0.96 -0.14 -0.62 -0.23
2340 || orf19.4593.1 || || || Protein with a predicted role in mitochondrial respiratory chain complex II assembly; rat catheter biofilm induced || 1 0.30 0.13 -0.74 -1.61 0.02 -2.85 0.61 0.99 -0.30 0.56 1.28 0.78 0.39 -0.14 0.57 0.34
2341 || orf19.1411 || || || Putative cytochrome P450; Hap43-repressed gene || 1 0.09 -0.03 -1.05 -0.78 0.29 0.52 0.67 -0.38 0.45 0.53 0.57 -0.02 -0.16 0.51 0.43
2342 || orf19.3552 || || || Ortholog(s) have structural constituent of nuclear pore activity || 1 0.10 -0.13 -0.24 -0.38 0.41 -0.20 -0.04 0.36 -0.18 0.53 0.70 0.34 0.31 0.56 0.33 0.33
2343 || orf19.4086 || || || Ortholog(s) have cytoplasm localization || 1 -0.03 0.05 -0.52 -0.36 0.68 -0.56 0.53 0.21 0.51 0.59 0.49 0.12 0.61 0.28 0.50 0.19
2344 || orf19.687 || || || Ortholog of C. dubliniensis CD36 : Cd36_62090, C. parapsilosis CDC317 : CPAR2_602150, Candida tenuis NRRL Y-1498 : CANTEDRAFT_112751 and Debaryomyces hansenii CBS767 : DEHA2F11814g || 1 0.80 0.52 0.05 -0.07 1.23 -0.43 0.75 0.74 0.56 1.74 0.90 0.31 0.88 1.03 1.03 0.34
2345 || orf19.5783 || || || Ortholog(s) have protein-arginine omega-N monomethyltransferase activity and role in peptidyl-arginine methylation || 1 0.36 0.44 0.08 0.32 0.36 0.26 0.30 0.56 0.17 0.78 0.64 0.06 0.01 0.48 0.79 0.06
2346 || orf19.6573 || BEM2 || || Putative Rho1p GTPase activating protein (GAP); serum-induced transcript; Spider biofilm induced; flow model biofilm repressed || 1 0.29 0.56 -0.11 0.31 0.86 0.08 0.48 0.68 0.24 0.88 1.19 0.23 0.41 0.12 1.13 0.36
2347 || orf19.1938 || || || Ortholog of S.pombe SPCC825.05c; a predicted splicing coactivator; transcription repressed in azole-resistant strain overexpressing CDR1 and CDR2; induced by benomyl treatment || 1 0.37 0.67 -0.16 0.22 0.86 0.09 0.32 0.21 0.33 0.67 1.11 0.32 0.23 0.79 1.63 0.23
2348 || orf19.448 || CUE5 || || Predicted ubiquitin-binding protein; rat catheter biofilm repressed || 1 0.79 0.74 -0.10 0.00 0.65 0.05 0.49 0.38 0.05 0.15 0.57 0.37 0.12 0.11 0.99 0.41
2349 || orf19.6351 || || || Ortholog of C. dubliniensis CD36 : Cd36_11880, Candida tenuis NRRL Y-1498 : cten_CGOB_00231, Debaryomyces hansenii CBS767 : DEHA2D04928g and Pichia stipitis Pignal : PICST_29234 || 1 1.05 0.96 -0.01 -0.21 0.85 -0.13 0.74 0.90 -0.08 -0.17 0.76 0.14 0.86 0.14 1.12 0.56
2350 || orf19.2907.1 || || || Ortholog(s) have chromatin DNA binding activity, role in positive regulation of transcription from RNA polymerase II promoter by pheromones, threonylcarbamoyladenosine metabolic process and EKC/KEOPS complex, nuclear chromatin localization || 1 0.28 0.37 -0.04 -0.09 0.71 0.10 0.45 0.45 -0.20 0.04 0.44 0.22 0.36 0.07 0.61 0.36
2351 || orf19.3764 || GSG1 || || Putative subunit of the TRAPP complex; involved in targeting of ER-to-Golgi transport vesicles; flow model biofilm induced || 1 0.56 0.62 -0.04 -0.60 0.38 0.02 0.45 0.72 -0.09 -0.07 0.79 0.60 0.54 0.04 0.93 0.41
2352 || orf19.764 || || || Ortholog(s) have clathrin-coated vesicle, cytoplasm localization || 1 0.63 0.81 0.07 -0.51 0.57 0.23 0.51 0.43 -0.05 0.08 0.50 0.52 0.54 0.35 0.80 0.72
2353 || orf19.6801 || RPD31 || || Putative histone deacetylase; involved in regulation of white-opaque switch; Spider biofilm repressed || 1 0.49 0.74 0.08 -0.25 0.31 0.16 0.32 0.22 0.16 -0.02 0.50 0.43 0.47 0.35 0.29 0.59
2354 || orf19.670 || SMT3 || || SUMO, small ubiquitin-like protein; Smt3p-conjugated proteins localize to septation site and mother side of bud neck; C. albicans septins appear not to be Smt3p-modified, in contrast to S. cerevisiae septins || 1 1.18 1.23 -0.15 -0.27 0.29 -0.10 1.04 1.22 0.16 -0.09 1.03 0.26 0.87 0.44 0.57 0.58
2355 || orf19.5617 || || || Ortholog(s) have methylated histone residue binding, transcription factor binding activity || 1 0.27 0.56 0.16 -0.30 0.74 -0.02 0.60 0.66 0.09 -0.14 1.09 0.73 0.50 -0.10 0.46 0.33
2356 || orf19.4497 || MED8 || || Ortholog(s) have RNA polymerase II core promoter proximal region sequence-specific DNA binding, RNA polymerase II transcription corepressor activity, TBP-class protein binding, structural molecule activity || 1 0.33 0.19 -0.05 -0.11 0.29 0.20 0.48 0.55 0.14 0.09 0.78 0.67 0.51 0.10 0.53 0.86
2357 || orf19.2433 || || || Ortholog of C. dubliniensis CD36 : Cd36_05790, C. parapsilosis CDC317 : CPAR2_103730, Pichia stipitis Pignal : PICST_28344, Candida tropicalis MYA-3404 : CTRG_04275 and Candida albicans WO-1 : CAWG_00795 || 1 0.71 0.23 -0.29 -0.61 0.32 0.09 0.31 1.19 0.31 0.46 1.39 0.82 0.78 -0.00 0.64 1.66
2358 || orf19.57 || PSF2 || || Ortholog(s) have role in DNA-dependent DNA replication, cellular protein localization, double-strand break repair via break-induced replication, meiotic chromosome segregation || 1 0.95 1.24 -0.04 -0.83 0.46 0.05 1.10 1.22 0.11 0.45 1.90 0.76 1.14 0.15 0.10 1.51
2359 || orf19.4518 || || || Protein kinase of unknown function; mutants are viable || 1 -0.25 -0.05 -0.66 -0.52 0.62 0.03 0.77 0.61 0.29 0.27 0.71 0.47 0.46 0.32 0.43 1.03
2360 || orf19.387 || GCR3 || || Functional homolog of S. cerevisiae Gcr3, which acts in regulation of glycolytic genes; no intron predicted, in contrast to intron in S. cerevisiae GCR3 gene || 1 -0.04 0.23 -0.49 -0.53 0.54 -0.04 0.69 0.60 0.76 0.24 0.82 0.50 0.43 0.37 0.30 0.58
2361 || orf19.4958 || ECM25 || || Non-essential protein involved in cell morphogenesis || 1 0.13 0.10 -0.05 -1.20 0.84 0.59 1.46 0.62 0.80 0.94 1.48 0.81 1.25 0.97 0.95 1.34
2362 || orf19.3260 || || || Ortholog(s) have phosphopantothenoylcysteine decarboxylase activity, role in coenzyme A biosynthetic process, response to salt stress and phosphopantothenoylcysteine decarboxylase complex localization || 1 0.29 0.33 -0.24 -0.76 0.52 0.66 0.73 0.41 0.80 0.51 0.57 0.48 0.02 1.05 0.86 0.98
2363 || orf19.1276 || || || Protein with a selenoprotein domain and a thioredoxin-like fold domain; similar to S. cerevisiae Vhs3p, which is a putative phosphopantothenoylcysteine decarboxylase || 1 0.25 -0.23 -0.31 -0.58 0.75 0.55 0.91 0.89 0.57 0.74 0.67 0.73 0.03 0.46 1.50 1.26
2364 || orf19.6982 || || || Ortholog(s) have ribosome binding activity and mitochondrion localization || 1 -0.10 0.45 -0.61 -0.34 0.79 0.72 0.51 1.54 0.57 1.33 0.73 1.67 0.56 1.08 1.52 1.36
2365 || orf19.2112 || || || snRNP U5 splicing factor component; involved in positioning the 3' splice site during the 2nd catalytic step of splicing; Spider biofilm induced || 1 -0.10 0.00 -0.62 0.40 0.35 0.33 0.42 0.34 0.74 0.61 0.85 0.54 0.37 0.62 0.91
2366 || orf19.6590 || VMA22 || || Ortholog(s) have unfolded protein binding activity, role in vacuolar acidification, vacuolar proton-transporting V-type ATPase complex assembly and extrinsic to endoplasmic reticulum membrane localization || 1 0.16 0.04 -0.72 -0.51 1.08 0.99 0.43 0.50 0.68 0.83 1.15 0.86 0.65 0.81 0.71 0.74
2367 || orf19.1900 || || || Ortholog(s) have RNA methyltransferase activity, role in 7-methylguanosine cap hypermethylation, meiosis, nucleologenesis, regulation of telomere maintenance via telomerase and nucleolus localization || 1 -0.25 -0.10 -0.70 -0.65 0.58 0.33 0.51 0.39 0.27 0.85 0.46 0.63 0.10 0.51 0.30 0.72
2368 || orf19.5765 || NUP82 || || Linker nucleoporin of the nuclear pore complex; role in mRNA andexport from nucleus, protein import into nucleus, ribosomal large subunit export from nucleus, ribosomal small subunit export from nucleus; rat catheter biofilm repressed || 1 -0.11 -0.05 -0.24 -0.47 0.45 0.25 0.17 0.17 0.21 0.27 0.41 0.51 0.12 0.60 0.30 0.70
2369 || orf19.114 || || || Ortholog of C. dubliniensis CD36 : Cd36_61190, C. parapsilosis CDC317 : CPAR2_603230, Candida tenuis NRRL Y-1498 : cten_CGOB_00054 and Debaryomyces hansenii CBS767 : DEHA2E21142g || 1 -0.13 -0.19 -0.18 -0.39 0.50 0.29 0.53 0.07 0.46 0.45 0.61 0.55 0.13 0.51 0.71 0.63
2370 || orf19.1259 || || || Ortholog(s) have DNA binding, ubiquitin-protein ligase activity and role in histone catabolic process, histone ubiquitination, regulation of transcription from RNA polymerase II promoter in response to oxidative stress || 1 -0.14 -0.35 -0.59 -0.65 0.70 0.31 0.75 0.77 0.81 0.67 0.88 1.02 0.39 1.30 1.13 0.68
2371 || orf19.2834 || RPD3 || || Histone deacetylase; regulates frequency of white-to-opaque and opaque-to-white switching; greater expression in white cells than opaque cells; has conserved deacetylation motif || 1 -0.15 -0.55 -0.42 -0.39 0.54 0.48 0.89 0.64 0.81 0.34 0.59 0.64 0.12 0.69 0.57 0.40
2372 || orf19.580 || || || Protein of unknown function; mutants are viable; Spider biofilm induced || 1 0.15 -0.34 0.06 -0.05 0.46 0.35 0.50 0.85 0.38 0.50 0.71 0.87 0.28 0.75 0.55 1.00
2373 || orf19.245 || DDC1 || || Putative DNA damage checkpoint protein; transcript induced during filamentous growth; regulated by Nrg1, Tup1 || 1 0.15 0.03 -0.21 -0.44 0.47 0.19 0.20 0.63 0.53 0.64 0.91 1.12 0.40 0.79 -0.07 0.79
2374 || orf19.580 || || || Protein of unknown function; mutants are viable; Spider biofilm induced || 1 -0.17 -0.02 -0.12 -0.09 0.38 0.49 0.10 0.33 0.40 0.29 0.47 0.57 0.29 0.42 0.01 0.56
2375 || orf19.1087 || || || Ortholog of C. parapsilosis CDC317 : CPAR2_601130, C. dubliniensis CD36 : Cd36_64620, Lodderomyces elongisporus NRLL YB-4239 : LELG_04885 and Candida orthopsilosis Co 90-125 : CORT_0F02130 || 1 -0.26 0.13 -0.17 -0.39 1.42 0.92 0.72 0.34 0.89 0.62 0.38 0.57 0.69 0.75 0.79 0.98
2376 || orf19.3817 || || || Ortholog(s) have cytoplasm, nucleolus localization || 1 -0.11 0.06 0.16 -0.21 0.67 0.76 0.53 0.51 0.22 0.60 0.90 0.24 0.38 0.74 0.66 0.43
2377 || orf19.3817 || || || Ortholog(s) have cytoplasm, nucleolus localization || 1 -0.06 -0.11 0.24 0.31 0.45 0.76 0.63 0.73 0.47 0.47 0.70 0.57 0.59 0.83 0.41 0.54
2378 || orf19.4875 || || || Ortholog(s) have role in mRNA splicing, via spliceosome and U2-type spliceosomal complex localization || 1 -0.14 0.14 0.23 0.29 0.73 1.38 0.38 0.96 0.71 1.11 0.66 1.12 0.66 1.68 0.53 1.18
2379 || orf19.6982 || || || Ortholog(s) have ribosome binding activity and mitochondrion localization || 1 0.38 -0.14 0.18 -0.20 0.51 1.38 0.87 0.99 1.35 1.53 0.69 1.46 0.90 1.34 1.00 1.34
2380 || orf19.6726 || || || Ortholog(s) have DNA secondary structure binding activity || 1 -0.06 0.27 0.22 -0.12 0.40 0.66 0.28 0.45 0.72 0.44 0.29 0.38 0.61 0.68 0.17 0.37
2381 || orf19.6407 || || || Ortholog(s) have role in ribosomal large subunit biogenesis and cytoplasm, cytosolic large ribosomal subunit, preribosome, large subunit precursor localization || 1 0.23 0.14 0.12 -0.09 0.40 0.31 0.42 0.56 0.55 0.59 0.45 0.37 0.90 1.03 0.66 0.28
2382 || orf19.1150.1 || || || Ortholog of C. dubliniensis CD36 : Cd36_10990, C. parapsilosis CDC317 : CPAR2_804585, Candida tenuis NRRL Y-1498 : cten_CGOB_00256 and Debaryomyces hansenii CBS767 : DEHA2F10406g || 1 0.19 0.41 0.07 0.07 0.39 0.49 0.33 0.28 0.50 0.63 0.69 0.76 0.74 0.87 0.48 -0.04
2383 || orf19.2001 || || || Has domain(s) with predicted L-ascorbic acid binding, iron ion binding, oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen and 2-oxoglutarate as one donor, more || 1 0.10 0.18 -0.06 0.00 0.17 0.10 0.26 0.36 0.19 0.42 0.37 0.60 0.16 0.46 0.61 -0.05
2384 || orf19.6013 || || || Ortholog(s) have cytosol, nucleolus localization || 1 -0.04 0.26 0.24 -0.03 0.30 0.66 0.67 1.20 0.25 0.82 0.98 1.17 0.56 0.63 1.09 0.04
2385 || orf19.789.1 || || || Ortholog(s) have signal sequence binding activity, role in protein targeting to ER and signal recognition particle, endoplasmic reticulum targeting localization || 1 -0.03 0.21 0.26 -0.23 0.56 0.22 0.36 0.57 0.58 0.91 0.61 0.84 1.01 0.28 0.81 -0.02
2386 || orf19.1086 || || || Ortholog(s) have role in protein deubiquitination, regulation of ER to Golgi vesicle-mediated transport, regulation of retrograde vesicle-mediated transport, Golgi to ER, ribophagy and cytoplasm localization || 1 0.59 0.28 -0.03 0.04 0.26 0.02 0.31 0.29 0.49 0.50 0.49 0.52 0.50 0.14 0.50 0.20
2387 || orf19.6255 || || || Putative protein of unknown function; Hap43p-repressed gene || 1 0.59 0.48 -0.00 -0.47 0.62 0.16 0.38 0.97 0.93 0.43 0.75 0.59 0.63 0.12 0.63 0.64
2388 || orf19.6313 || MNT4 || || Predicted alpha-1,3-mannosyltransferase with a role in protein glycosylation; induced in low iron || 1 0.30 0.21 -0.54 -0.48 0.94 -0.03 0.86 0.98 0.78 1.06 0.50 0.98 0.98 -0.09 1.22 0.32
2389 || orf19.1963 || GDS1 || || Putative mitochondrial protein; Hap43-repressed gene; Spider biofilm induced || 1 0.85 0.94 0.19 0.25 0.82 0.32 0.97 0.66 0.24 0.11 0.98 0.44 1.77 -0.01 1.27 0.60
2390 || orf19.1963 || GDS1 || || Putative mitochondrial protein; Hap43-repressed gene; Spider biofilm induced || 1 0.92 0.86 0.02 -0.06 0.69 0.28 1.19 0.45 0.08 0.51 1.14 0.72 1.69 0.21 1.47 0.84
2391 || orf19.3569 || || || Protein of unknown function; S. cerevisiae YLR407W mutants have abnormal budding; constitutive expression independent of MTL or white-opaque status; Spider biofilm induced || 1 0.56 0.56 -0.43 -0.07 0.88 0.12 0.88 1.07 0.43 0.29 0.86 0.73 1.81 0.42 1.36 0.78
2392 || orf19.3473 || || || Ortholog(s) have enzyme activator activity, histone acetyltransferase activity, structural molecule activity || 1 0.20 0.17 0.12 0.01 0.45 0.02 0.58 0.57 0.10 0.16 0.89 0.72 0.98 0.34 0.71 0.63
2393 || orf19.4488 || || || Predicted ortholog of S. cerevisiae Swi3, subunit of the SWI/SNF chromatin remodeling complex; possibly an essential gene, disruptants not obtained by UAU1 method || 1 0.55 0.63 0.06 0.18 0.57 0.03 0.41 0.74 0.35 0.27 1.04 0.82 1.41 0.90 1.06 0.54
2394 || orf19.5432 || TPT1 || || tRNA 2'-phosphotransferase; enzyme of tRNA splicing; functionally complements viability of S. cerevisiae tpt1 null mutant || 1 0.27 0.40 0.01 -0.08 0.39 0.16 0.36 0.25 0.06 -0.03 0.62 0.43 0.63 0.38 0.55 0.24
2395 || orf19.940 || BUD2 || || GTPase activating protein (GAP) for Rsr1; negative regulator of filament branching, acts in hyphal growth guidance; required for wild-type budding pattern; induced in low iron; regulated by tyrosol and cell density || 1 0.43 0.43 0.08 -0.39 0.63 0.28 0.26 0.33 0.23 0.06 0.38 0.43 0.74 0.77 0.35 0.21
2396 || orf19.4585 || TFG1 || || Protein similar to S. cerevisiae Tfg1p, which is part of transcription factor TFIIF; transposon mutation affects filamentous growth; possibly an essential gene, disruptants not obtained by UAU1 method || 1 0.32 0.43 -0.06 -0.59 0.64 0.13 0.85 0.61 0.21 -0.11 0.54 0.36 1.32 1.28 0.66 0.18
2397 || orf19.4585 || TFG1 || || Protein similar to S. cerevisiae Tfg1p, which is part of transcription factor TFIIF; transposon mutation affects filamentous growth; possibly an essential gene, disruptants not obtained by UAU1 method || 1 0.60 0.66 -0.01 -0.56 0.79 0.03 0.89 0.66 0.33 0.17 0.72 0.15 1.56 0.88 0.76 -0.23
2398 || orf19.6268 || || || Putative cohesin complex subunit; expression downregulated in an ssr1 null mutant || 1 0.38 0.43 0.34 0.02 0.52 -0.10 0.66 0.52 0.54 0.07 0.47 0.56 1.22 0.66 0.58 -0.05
2399 || orf19.7111 || || || Putative mitochondrial outer membrane protein membrane fission effector; possibly an essential gene, disruptants not obtained by UAU1 method || 1 0.45 0.58 -0.13 -0.10 0.77 0.22 1.59 1.22 0.82 0.34 0.87 0.21 1.78 0.61 0.79 -0.23
2400 || orf19.7111 || || || Putative mitochondrial outer membrane protein membrane fission effector; possibly an essential gene, disruptants not obtained by UAU1 method || 1 0.57 0.79 -0.11 -0.18 0.87 0.17 1.38 1.16 0.96 0.49 0.92 0.24 1.69 0.53 0.67 0.41
2401 || orf19.7111 || || || Putative mitochondrial outer membrane protein membrane fission effector; possibly an essential gene, disruptants not obtained by UAU1 method || 1 0.48 0.57 -0.25 -0.23 0.67 0.23 1.45 1.31 0.88 0.40 0.74 0.34 1.48 0.69 0.79 0.50
2402 || orf19.4415 || MED3 || || RNA polymerase II mediator complex subunit || 1 0.24 0.25 0.23 0.27 0.37 0.07 0.77 0.65 0.62 0.49 0.92 0.29 0.75 0.63 1.02 0.12
2403 || orf19.4914 || || || Ortholog(s) have role in cellular response to DNA damage stimulus || 1 0.41 0.37 -0.06 0.21 0.94 -0.36 0.41 0.76 0.83 0.44 1.25 0.87 1.06 1.06 0.23
2404 || orf19.6972 || SMI1B || || Putative cell wall assembly regulatory protein; Rim101-repressed; possibly an essential gene, disruptants not obtained by UAU1 method || 1 0.40 0.09 -0.36 0.31 0.60 -0.97 0.57 0.77 0.17 0.92 1.07 0.84 1.30 0.39 0.82 -0.08
2405 || orf19.5126 || || || Putative adhesin-like protein || 1 0.55 0.82 -0.04 0.35 0.13 -0.49 0.88 0.83 0.30 1.39 1.01 0.89 1.40 0.46 0.94 -0.15
2406 || orf19.4855 || BUD31 || || Bud31 ortholog; not subject to mating-type regulation, in contrast to S. cerevisiae Bud31 which has a role in specifying the bud site; Spider biofilm induced || 1 0.46 0.36 -0.04 0.13 0.69 0.01 0.88 0.77 0.15 1.09 0.97 0.63 1.93 0.31 0.98 -0.38
2407 || orf19.1441 || || || Ortholog of C. dubliniensis CD36 : Cd36_16230, C. parapsilosis CDC317 : CPAR2_213950, Candida tenuis NRRL Y-1498 : CANTEDRAFT_112720 and Debaryomyces hansenii CBS767 : DEHA2A01848g || 1 -0.05 0.15 -0.43 -0.35 0.19 -0.10 1.36 0.73 0.61 0.87 0.98 0.94 1.69 0.49 0.92 -0.01
2408 || orf19.1441 || || || Ortholog of C. dubliniensis CD36 : Cd36_16230, C. parapsilosis CDC317 : CPAR2_213950, Candida tenuis NRRL Y-1498 : CANTEDRAFT_112720 and Debaryomyces hansenii CBS767 : DEHA2A01848g || 1 0.41 0.38 -0.34 -0.53 0.21 0.03 0.86 0.93 0.32 0.54 1.01 1.01 1.35 -0.16 0.80 0.19
2409 || orf19.6295 || MAS2 || || Putative processing peptidase, catalytic (alpha) subunit; protein level decreases in stationary phase cultures || 1 0.15 -0.01 -0.30 -0.41 0.03 -0.13 0.31 0.36 0.47 0.82 0.64 1.02 0.35 0.17 0.76 0.07
2410 || orf19.7375 || || || Putative U1A component of the U1 snRNP, involved in splicing; contains two RNA recognition motifs (RRMs); ortholog of S. cerevisiae MUD1 || 1 0.12 0.05 -0.23 -0.21 -0.16 -0.32 0.13 0.35 0.36 0.46 0.57 0.60 0.37 0.32 0.44 -0.07
2411 || orf19.1828 || BUD16 || || Putative pyridoxal kinase; a key enzyme in pyridoxal 5'-phosphate synthesis, the active form of vitamin B6; involved in bud-site selection and genome integrity in S. cerevisiae; induced by alpha pheromone in SpiderM medium || 1 -0.29 0.08 -0.50 -0.41 0.24 -0.70 0.57 0.43 0.87 0.83 0.80 1.26 0.85 0.46 0.51 0.36
2412 || orf19.2438 || || || Ortholog(s) have mitochondrion, ribosome localization || 1 0.16 0.28 -0.03 -0.34 0.10 -0.47 0.72 0.87 0.58 0.59 1.01 0.56 0.79 0.52 0.59 -0.01
2413 || orf19.4529 || || || Ortholog of Srp21, signal recognition particle subunit, functions in protein targeting to the endoplasmic reticulum membrane; predicted adhesin-like protein; mutants are viable || 1 0.35 0.21 0.39 -0.05 0.25 -0.87 1.14 1.37 1.12 1.10 1.50 1.23 1.32 0.41 1.11 0.34
2414 || orf19.6804 || || || Ortholog(s) have signal sequence binding activity, role in protein targeting to ER and cytosol, nuclear periphery, signal recognition particle, endoplasmic reticulum targeting localization || 1 0.17 0.42 0.24 -0.02 0.19 -0.44 0.41 0.81 0.41 0.96 0.99 1.16 0.46 0.33 0.96 0.46
2415 || orf19.6804 || || || Ortholog(s) have signal sequence binding activity, role in protein targeting to ER and cytosol, nuclear periphery, signal recognition particle, endoplasmic reticulum targeting localization || 1 0.18 0.35 0.14 0.12 0.16 -0.33 0.35 0.60 0.47 1.05 1.00 1.27 0.64 0.25 0.78 0.58
2416 || orf19.6804 || || || Ortholog(s) have signal sequence binding activity, role in protein targeting to ER and cytosol, nuclear periphery, signal recognition particle, endoplasmic reticulum targeting localization || 1 -0.10 0.11 0.17 0.04 -0.15 -0.39 0.58 0.40 0.21 0.62 0.90 1.00 0.33 0.21 0.62 0.59
2417 || orf19.4882 || || || TFIIE small subunit; involved in RNA polymerase II transcription initiation; Spider biofilm induced || 1 -0.17 -0.14 -0.69 -0.75 0.61 -0.01 0.45 0.32 0.19 -0.06 0.82 0.44 0.28 0.31 0.63 0.53
2418 || orf19.3294 || MBF1 || || Putative transcriptional coactivator; caspofungin repressed || 1 -0.05 -0.05 -0.80 -1.04 0.37 -0.02 0.78 0.72 0.11 0.04 1.53 0.99 0.24 0.37 1.24 0.59
2419 || orf19.3930 || YUH2 || || Putative ubiquitin C-terminal hydrolase; sumoylation target || 1 0.06 -0.00 -0.54 -0.52 0.59 0.10 0.74 0.64 0.31 0.38 1.17 0.60 0.22 0.33 0.90 0.74
2420 || orf19.5368 || || || Ortholog of Vms1; component of a Cdc48-complex involved in protein quality control in S. cerevisiae; Spider biofilm repressed || 1 -0.09 -0.03 -0.82 -0.60 0.41 0.06 0.59 0.73 0.21 0.48 0.83 0.45 0.22 0.27 0.84 0.51
2421 || orf19.5368 || || || Ortholog of Vms1; component of a Cdc48-complex involved in protein quality control in S. cerevisiae; Spider biofilm repressed || 1 -0.07 -0.03 -0.70 -0.56 0.54 0.01 0.69 0.68 0.59 0.68 0.82 0.51 0.11 0.54 1.05 0.48
2422 || orf19.325 || || || Putative mRNA cleavage and polyadenlylation factor; heterozygous null mutant exhibits hypersensitivity to parnafungin and cordycepin in the C. albicans fitness test || 1 -0.28 -0.35 -0.99 -0.76 0.36 -0.06 0.75 0.78 0.39 0.44 1.14 0.78 0.50 0.79 0.88 0.37
2423 || orf19.1532 || SAM37 || || Protein of the mitochondrial outer membrane, component of the Sorting and Assembly Machinery (SAM) involved in insertion of proteins into the outer membrane; mutants show loss of mtDNA || 1 -0.26 -0.36 -1.10 -0.95 0.38 0.31 1.02 0.77 0.48 0.47 1.16 1.08 0.35 0.58 0.92 0.94
2424 || orf19.1532 || SAM37 || || Protein of the mitochondrial outer membrane, component of the Sorting and Assembly Machinery (SAM) involved in insertion of proteins into the outer membrane; mutants show loss of mtDNA || 1 -0.06 -0.24 -1.40 -1.29 0.28 0.02 1.30 0.80 0.29 0.48 1.05 1.00 0.62 0.67 0.86 0.66
2425 || orf19.2557 || SEC65 || || Component of the protein-targeting Signal Recognition Particle (SRP); similar to mammalian Srp19; functional homolog of S. cerevisiae Sec65; Tbf1-induced || 1 -0.05 0.18 -0.70 -0.61 0.69 0.44 0.69 0.67 0.09 0.72 1.00 0.76 0.59 0.56 1.23 0.40
2426 || orf19.1383 || || || Protein of unknown function; induced by alpha pheromone in SpiderM medium || 1 0.15 0.13 -0.59 -0.76 1.20 0.54 0.57 1.13 0.22 0.52 1.12 0.88 0.22 0.65 1.32 0.66
2427 || orf19.1458 || || || Ortholog(s) have tRNA-specific adenosine deaminase activity, role in tRNA modification and cytoplasm, nucleus localization || 1 0.02 0.13 -0.87 -0.65 0.52 0.51 0.22 0.98 0.40 0.39 0.99 1.00 0.45 0.46 1.09 0.72
2428 || orf19.2516 || || || Has domain(s) with predicted role in cell redox homeostasis || 1 0.47 0.06 -0.75 -0.76 0.37 0.26 0.77 1.01 0.31 0.20 1.57 1.04 0.96 0.57 1.67 0.85
2429 || orf19.3449 || || || Ortholog(s) have ubiquitin-protein ligase activity, role in histone catabolic process, histone ubiquitination and cytoplasm, ribosome localization || 1 -0.14 0.14 -1.36 -1.40 0.49 0.22 1.64 1.05 0.10 0.50 1.75 0.87 1.90 0.38 1.55 0.38
2430 || orf19.789.1 || || || Ortholog(s) have signal sequence binding activity, role in protein targeting to ER and signal recognition particle, endoplasmic reticulum targeting localization || 1 0.20 -0.31 -0.83 -0.71 0.23 0.42 1.26 1.02 0.15 0.64 1.29 1.05 1.79 0.81 1.55 0.64
2431 || orf19.5483 || || || Ortholog(s) have GTPase activity, ribosome binding activity, role in positive regulation of translation and mitochondrial matrix, mitochondrial ribosome localization || 1 -0.06 -0.22 -0.49 -0.76 0.68 0.53 1.08 0.82 0.55 0.78 0.97 0.69 1.12 0.50 1.14 0.34
2432 || orf19.2112 || || || snRNP U5 splicing factor component; involved in positioning the 3' splice site during the 2nd catalytic step of splicing; Spider biofilm induced || 1 -0.14 -0.22 -0.71 -0.43 0.83 0.06 0.97 0.87 0.66 0.60 1.15 0.44 0.99 0.56 1.38 0.43
2433 || orf19.1707 || || || Ortholog of Candida albicans WO-1 : CAWG_02476 || 1 -0.18 -0.05 -0.50 -0.57 0.60 -0.28 0.61 0.60 -0.00 0.31 0.81 0.36 0.38 0.40 0.82 0.14
2434 || orf19.3147 || || || Ortholog of C. dubliniensis CD36 : Cd36_21050, C. parapsilosis CDC317 : CPAR2_104310, Candida tenuis NRRL Y-1498 : CANTEDRAFT_104515 and Debaryomyces hansenii CBS767 : DEHA2F01650g || 1 -0.10 -0.17 -0.25 -0.37 0.65 0.26 0.55 0.73 0.27 0.57 1.01 0.42 0.59 0.05 0.65 0.46
2435 || orf19.1678 || || || Protein of unknown function; transcript detected on high-resolution tiling arrays || 1 0.27 0.25 -0.48 -0.45 1.19 0.45 0.83 0.93 0.24 0.23 1.26 0.61 0.77 0.01 0.99 1.03
2436 || orf19.1619 || || || Putative kinase subunit of RNA polymerase II carboxy-terminal domain kinase I; possibly an essential gene, disruptants not obtained by UAU1 method || 1 -0.20 -0.09 -0.45 -0.30 1.11 0.19 0.84 0.69 0.33 0.17 1.50 0.63 0.96 0.01 1.19 0.75
2437 || orf19.7034 || || || Putative eIF4E-associated protein;, accelerates mRNA degradation by promoting decapping; Spider biofilm repressed || 1 -0.06 -0.03 -0.39 -0.26 0.50 0.24 0.65 0.52 0.22 0.08 0.84 0.49 0.65 0.18 1.06 0.39
2438 || orf19.5213 || || || Putative protein of unknown function; transcript is upregulated in clinical isolates from HIV+ patients with oral candidiasis || 1 0.11 -0.00 -0.19 -0.29 0.51 0.37 0.60 0.44 0.13 -0.00 0.76 0.63 0.45 -0.19 0.95 0.50
2439 || orf19.4628 || || || Putative cleavage and polyadenylation factor; heterozygous null mutant exhibits hypersensitivity to parnafungin and cordycepin in the C. albicans fitness test; possibly an essential gene, disruptants not obtained by UAU1 method || 1 -0.04 -0.12 -0.12 -0.31 0.23 0.23 0.39 0.50 0.41 0.32 0.71 0.64 0.58 -0.12 0.87 0.49
2440 || orf19.1658 || || || Ortholog(s) have cell cortex, cellular bud neck, cellular bud tip, mating projection tip localization || 1 -0.24 -0.25 -0.81 -0.34 0.02 -0.33 0.50 0.70 0.26 0.47 1.20 0.81 0.84 0.48 1.50 0.71
2441 || orf19.1658 || || || Ortholog(s) have cell cortex, cellular bud neck, cellular bud tip, mating projection tip localization || 1 0.19 0.08 -0.60 -0.26 0.43 -0.04 0.85 0.64 0.36 0.76 1.27 0.97 1.27 0.12 1.83 0.55
2442 || orf19.1658 || || || Ortholog(s) have cell cortex, cellular bud neck, cellular bud tip, mating projection tip localization || 1 0.28 0.29 -0.57 -0.03 0.19 -0.22 0.76 0.57 0.15 0.44 1.18 0.55 0.97 0.13 1.51 0.65
2443 || orf19.1396 || || || Ortholog(s) have ARF GTPase activator activity, role in ER to Golgi vesicle-mediated transport, intra-Golgi vesicle-mediated transport and Golgi apparatus, clathrin-coated vesicle localization || 1 0.16 0.27 0.09 0.08 0.65 -0.52 1.03 0.90 0.24 0.49 1.23 0.69 0.81 0.33 1.00 0.73
2444 || orf19.6531.1 || TOM7 || || Predicted component of the TOM (translocase of outer membrane) complex involved in protein translocation into mitochondria; flucytosine induced || 1 0.42 0.29 -0.59 -0.25 0.69 -0.45 1.42 2.02 0.30 0.81 2.03 1.05 0.48 -0.18 0.67 -0.07
2445 || orf19.6183 || TIM8 || || Predicted mitochondrial intermembrane space protein with role in protein import into mitochondrial inner membrane and cytosol || 1 0.43 0.28 -0.52 -0.35 0.59 -0.43 1.47 1.98 1.30 1.37 2.25 1.07 0.47 0.17 1.07 0.15
2446 || orf19.5161 || || || Ortholog(s) have structural constituent of ribosome activity and mitochondrial large ribosomal subunit localization || 1 0.22 0.35 -0.22 -0.20 0.23 -0.39 0.89 1.17 0.41 0.73 0.94 0.67 0.19 0.01 0.62 0.54
2447 || orf19.4025 || PRE1 || || Putative beta 4 subunit of the 20S proteasome; Rim101-induced at acid pH; flucytosine induced; amphotericin B repressed || 1 0.24 0.31 -0.64 -0.08 0.05 -0.43 0.54 0.79 0.43 0.35 0.90 0.50 0.40 0.09 0.61 0.18
2448 || orf19.4529 || || || Ortholog of Srp21, signal recognition particle subunit, functions in protein targeting to the endoplasmic reticulum membrane; predicted adhesin-like protein; mutants are viable || 1 0.76 0.38 -1.53 -0.61 0.20 -1.80 1.87 2.91 1.09 1.70 2.16 1.56 1.33 0.88 2.10 0.74
2449 || orf19.5161 || || || Ortholog(s) have structural constituent of ribosome activity and mitochondrial large ribosomal subunit localization || 1 0.24 0.09 -0.48 -0.52 0.40 -0.50 0.94 1.59 0.47 0.87 1.01 0.51 0.49 0.32 0.70 0.41
2450 || orf19.1828 || BUD16 || || Putative pyridoxal kinase; a key enzyme in pyridoxal 5'-phosphate synthesis, the active form of vitamin B6; involved in bud-site selection and genome integrity in S. cerevisiae; induced by alpha pheromone in SpiderM medium || 1 0.21 0.08 -0.74 -0.65 0.28 -0.46 0.68 1.27 0.48 0.33 1.05 0.60 0.53 0.01 0.64 0.36
2451 || orf19.6916 || || || Ortholog(s) have unfolded protein binding activity, role in mitochondrial proton-transporting ATP synthase complex assembly and mitochondrion localization || 1 0.16 0.16 -0.37 -0.52 0.06 -0.11 1.16 1.09 0.17 0.63 0.94 0.82 0.63 0.58 0.86 0.21
2452 || orf19.4851 || TFA1 || || Protein with polyglutamate motifs and abundant Ser/Thr residues; described as a subunit of TFIIE, which is a basal transcription initiation factor of RNA Polymerase II; possibly an essential gene, disruptants not obtained by UAU1 method || 1 -0.17 -0.12 -1.22 -0.54 0.37 -0.27 1.03 1.25 0.25 0.71 1.75 0.82 0.18 0.66 0.87 0.85
2453 || orf19.400 || GCF1 || || HMG box mitochondrial protein; binds to mt DNA and the HWP1 promoter; mutant phenotype and functional complementation of an S. cerevisiae abf2 mutation suggest role in mt genome replication, maintenance; flow and Spider biofilm repressed || 1 -0.07 0.00 -1.41 -1.36 0.26 -0.75 1.74 1.78 0.31 0.37 2.32 0.81 1.03 0.88 0.74 0.77
2454 || orf19.400 || GCF1 || || HMG box mitochondrial protein; binds to mt DNA and the HWP1 promoter; mutant phenotype and functional complementation of an S. cerevisiae abf2 mutation suggest role in mt genome replication, maintenance; flow and Spider biofilm repressed || 1 -0.13 -0.03 -0.79 -0.80 0.17 -0.45 1.55 1.66 0.39 0.44 2.07 1.04 1.10 0.85 0.64 0.54
2455 || orf19.4796 || || || Putative eIF-4E-binding repressor of CAP-dependent translation; stationary phase enriched protein || 1 -0.02 0.18 -1.00 -0.67 0.28 -0.47 0.88 1.87 0.00 1.14 2.01 0.77 0.52 0.68 1.15 0.29
2456 || orf19.6748 || || || Ortholog(s) have role in ascospore formation, cellular response to cadmium ion, detoxification of cadmium ion || 1 0.17 0.06 -0.88 -0.40 0.19 -0.40 0.81 1.27 0.44 1.09 1.08 0.47 0.37 0.82 0.47 0.44
2457 || orf19.2694 || TYS1 || || Putative tRNA-Tyr synthetase; downregulated upon phagocytosis by murine macrophages; stationary phase enriched protein; Spider biofilm repressed || 1 0.06 0.14 -0.64 -0.57 0.09 -0.30 0.90 1.25 0.35 0.83 1.10 0.36 0.40 0.98 0.34 0.36
2458 || orf19.4021 || || || Ortholog of C. dubliniensis CD36 : Cd36_54870, C. parapsilosis CDC317 : CPAR2_100250, Debaryomyces hansenii CBS767 : DEHA2D13992g and Pichia stipitis Pignal : PICST_40400 || 1 0.18 0.40 -0.66 -0.60 0.34 -0.10 0.79 1.12 0.40 0.98 1.26 0.35 0.40 0.77 0.63 0.45
2459 || orf19.1707 || || || Ortholog of Candida albicans WO-1 : CAWG_02476 || 1 0.21 0.23 -0.59 -0.74 0.23 -0.28 0.68 0.96 -0.07 0.55 1.05 0.65 0.27 0.79 0.69 0.30
2460 || orf19.6612 || || || Putative mitochondrial protein; Hap43p-induced gene || 1 0.04 0.11 -1.08 -0.73 0.06 -0.45 0.91 1.50 -0.07 0.84 1.77 0.86 0.77 1.27 1.00 0.81
2461 || orf19.5160 || || || Ortholog(s) have role in G1/S transition of mitotic cell cycle, TOR signaling cascade, dephosphorylation, regulation of mitotic sister chromatid segregation, tRNA wobble uridine modification || 1 0.19 0.17 -0.65 -0.90 0.26 -0.35 0.98 1.06 0.19 0.78 1.46 0.84 0.74 0.85 0.85 0.92
2462 || orf19.6612 || || || Putative mitochondrial protein; Hap43p-induced gene || 1 0.61 0.46 -0.54 -0.47 0.19 -0.27 0.89 1.50 0.16 1.07 1.96 0.92 1.11 0.84 1.09 1.00
2463 || orf19.6623 || || || Ortholog(s) have RNA polymerase II core binding activity, role in regulation of transcription by chromatin organization, transcription elongation from RNA polymerase II promoter and transcription elongation factor complex localization || 1 0.36 0.32 -0.54 -0.56 0.28 -0.10 1.41 1.94 0.69 0.75 2.20 1.10 1.02 1.09 0.89 1.02
2464 || orf19.6623 || || || Ortholog(s) have RNA polymerase II core binding activity, role in regulation of transcription by chromatin organization, transcription elongation from RNA polymerase II promoter and transcription elongation factor complex localization || 1 -0.04 -0.10 -0.61 -0.45 -0.17 -0.32 1.34 1.76 0.68 0.98 2.12 0.95 0.83 1.16 0.87 0.99
2465 || orf19.7477 || YRB1 || || Functional homolog of S. cerevisiae Yrb1p; regulates Gsp1 GTPase activity and thereby affects nucleocytoplasmic transport and cytoskeletal dynamics; transcript is not regulated by white-opaque switch or by dimorphic transition || 1 0.33 0.22 -0.41 -0.31 0.19 -0.41 0.53 0.82 0.26 0.59 1.08 0.67 0.33 0.54 0.22 0.62
2466 || orf19.4635 || NIP1 || || Putative translation initiation factor; mutation confers hypersensitivity to roridin A and verrucarin A; genes encoding ribosomal subunits, translation factors, and tRNA synthetases are downregulated upon phagocytosis by murine macrophage || 1 0.75 0.88 -1.05 -1.08 1.06 -0.49 1.37 1.62 0.06 1.32 2.05 0.84 1.38 1.03 1.30 0.98
2467 || orf19.4021 || || || Ortholog of C. dubliniensis CD36 : Cd36_54870, C. parapsilosis CDC317 : CPAR2_100250, Debaryomyces hansenii CBS767 : DEHA2D13992g and Pichia stipitis Pignal : PICST_40400 || 1 0.19 0.40 -0.35 -0.14 0.39 0.03 0.99 1.28 0.56 1.12 1.27 0.22 0.88 0.85 0.26 0.51
2468 || orf19.7613 || HCR1 || || Putative translation initiation factor; repressed upon phagocytosis by murine macrophage; Spider biofilm repressed || 1 0.23 0.15 -0.39 -0.48 0.46 0.03 0.91 1.12 0.56 0.94 0.85 0.47 0.53 0.72 0.28 0.41
2469 || orf19.6345 || RPG1A || || Putative translation initiation factor; mutation confers hypersensitivity to roridin A and verrucarin A; repressed upon phagocytosis by murine macrophage; Spider biofilm repressed || 1 -0.19 -0.06 -0.99 -0.09 0.79 0.25 1.46 1.64 0.65 1.55 1.50 1.00 0.74 1.27 1.08 1.14
2470 || orf19.397 || || || Ortholog(s) have structural constituent of ribosome activity and cytosol, mitochondrial large ribosomal subunit, nucleus localization || 1 -0.08 0.19 -1.26 -0.89 1.17 0.47 1.78 2.60 1.29 1.51 2.14 1.09 1.11 0.61 1.43 0.83
2471 || orf19.51 || || || Ortholog(s) have role in mitochondrion organization, translational initiation and eukaryotic translation initiation factor 3 complex localization || 1 0.22 0.25 -1.10 -0.82 0.65 0.13 1.45 1.47 1.09 1.51 1.29 0.76 0.95 0.45 1.06 0.30
2472 || orf19.549 || || || Ortholog(s) have structural constituent of ribosome activity and mitochondrial inner membrane, mitochondrial large ribosomal subunit localization || 1 -0.04 0.24 -0.85 -0.69 0.43 -0.01 0.97 1.36 0.84 1.35 0.95 0.98 0.53 0.78 0.76 0.68
2473 || orf19.6461 || || || Ortholog(s) have unfolded protein binding activity, role in aerobic respiration, mitochondrial respiratory chain complex IV assembly, protein processing and mitochondrial inner membrane localization || 1 0.11 -0.05 -0.22 -0.42 0.30 -0.01 0.44 0.61 0.61 0.57 0.57 0.62 0.38 0.26 0.64 0.35
2474 || orf19.6357 || || || Ortholog(s) have role in mitotic DNA integrity checkpoint, negative regulation of protein import into nucleus during spindle assembly checkpoint, nucleocytoplasmic transport || 1 0.31 0.43 -0.19 -0.27 0.38 0.24 0.96 0.63 0.60 1.06 1.01 1.25 1.22 0.86 1.20 0.51
2475 || orf19.6587 || GIR2 || || Ortholog of S. cerevisiae Gir2; transposon mutation affects filamentous growth || 1 0.32 0.51 -0.23 0.06 0.14 -0.28 1.29 0.95 0.89 0.88 1.23 1.16 1.22 0.71 1.15 0.45
2476 || orf19.7477 || YRB1 || || Functional homolog of S. cerevisiae Yrb1p; regulates Gsp1 GTPase activity and thereby affects nucleocytoplasmic transport and cytoskeletal dynamics; transcript is not regulated by white-opaque switch or by dimorphic transition || 1 0.97 0.74 -0.43 -0.18 0.11 -0.25 1.65 2.07 0.54 0.98 1.57 0.88 1.36 0.51 0.57 0.83
2477 || orf19.1267.1 || || || Ortholog(s) have enzyme activator activity, role in iron-sulfur cluster assembly and extrinsic to mitochondrial inner membrane, mitochondrial matrix localization || 1 0.67 0.68 -0.42 -0.22 0.22 -0.37 1.44 1.60 0.33 0.59 1.27 0.50 0.70 0.53 1.22 0.41
2478 || orf19.6479 || SEC1 || || Ortholog(s) have SNARE binding activity and role in positive regulation of vesicle fusion, vesicle docking involved in exocytosis || 1 0.46 0.50 -0.32 -0.39 0.07 -0.45 0.99 1.15 0.39 0.39 1.00 0.49 0.77 0.87 0.80 0.38
2479 || orf19.2639.1 || || || Lsm (Like Sm) protein; predicted role in involved in mRNA decay; Spider biofilm repressed || 1 1.05 1.13 -0.48 -0.22 0.52 -0.42 1.78 2.57 0.60 0.97 2.75 1.09 1.42 1.48 1.21 0.87
2480 || orf19.3899 || SDC1 || || Putative COMPASS/SET1C histone methyltransferase complex subunit || 1 0.85 0.50 -0.08 0.10 0.44 -0.16 1.24 1.76 0.21 0.50 1.74 0.73 1.08 1.08 1.07 0.86
2481 || orf19.6294 || MYO1 || || Component of actomyosin ring at neck of newly-emerged bud || 1 1.17 1.33 -0.48 -0.04 0.88 -1.32 1.86 2.35 0.88 1.68 2.76 0.46 1.73 1.54 1.36 1.21
2482 || orf19.4046 || || || Putative transcription factor containing a Zn(2)-Cys(6) binuclear cluster || 1 0.47 0.85 -0.36 -0.19 0.12 -0.13 1.03 0.89 0.05 0.43 1.16 0.33 0.72 0.59 1.01 0.65
2483 || orf19.4969 || KEM1 || || 5'->3' exoribonuclease of cytoplasmic stress granules; role in filamentous growth; complements slow growth/mating of S. cerevisiae kem1 mutant; required for SD or Spider medium biofilm formation || 1 0.07 0.11 -0.22 -0.21 0.13 0.20 0.71 0.48 0.15 0.12 0.61 0.50 0.49 0.45 0.71 0.51
2484 || orf19.6250 || || || Ortholog(s) have eukaryotic initiation factor 4G binding, mRNA binding activity || 1 -0.08 0.21 -0.11 -0.26 0.47 0.15 1.10 0.87 0.13 0.17 1.34 0.62 0.68 0.54 1.21 0.71
2485 || orf19.4969 || KEM1 || || 5'->3' exoribonuclease of cytoplasmic stress granules; role in filamentous growth; complements slow growth/mating of S. cerevisiae kem1 mutant; required for SD or Spider medium biofilm formation || 1 0.19 0.09 -0.07 -0.26 0.31 0.06 0.68 0.94 0.20 0.05 0.83 0.41 0.70 0.36 0.63 0.67
2486 || orf19.5058 || SMI1 || || Cell wall biosynthesis protein; Hap43, caspofungin-repressed; Cyr1-induced in hyphal cells; reduced biofilm cell wall glucan in mutant; possibly essential (UAU1 method); flow model biofilm induced || 1 0.56 0.52 -0.18 -0.20 0.78 0.62 1.26 1.09 0.99 0.60 1.27 0.54 0.75 0.43 0.90 1.02
2487 || orf19.1491 || || || Ortholog(s) have RNA binding activity, role in mRNA splicing, via spliceosome and U1 snRNP, U2-type prespliceosome localization || 1 0.80 0.56 -0.35 -0.28 1.17 0.80 0.91 1.08 0.62 1.06 1.04 0.88 1.49 0.99 1.18 0.64
2488 || orf19.4958 || ECM25 || || Non-essential protein involved in cell morphogenesis || 1 0.15 0.36 -0.40 -0.34 1.10 0.60 1.30 0.71 0.72 0.56 1.25 0.98 1.03 1.09 1.18 0.53
2489 || orf19.6419.1 || || || Ortholog of C. parapsilosis CDC317 : CPAR2_205710, Candida tenuis NRRL Y-1498 : CANTEDRAFT_117073, Lodderomyces elongisporus NRLL YB-4239 : LELG_02945 and Debaryomyces hansenii CBS767 : DEHA2A11462g || 1 0.17 0.06 -0.26 -0.09 1.89 1.07 1.68 1.37 0.86 1.02 1.61 1.13 1.29 0.84 1.45 0.95
2490 || orf19.488 || MEX67 || || Nuclear export protein; has NTF2-like domain; interacts with Mtr2p via the NTF2-like domain || 1 0.62 0.21 -0.61 0.06 1.32 0.91 1.13 1.03 0.57 0.77 1.52 1.02 0.89 0.29 1.34 0.56
2491 || orf19.1276 || || || Protein with a selenoprotein domain and a thioredoxin-like fold domain; similar to S. cerevisiae Vhs3p, which is a putative phosphopantothenoylcysteine decarboxylase || 1 0.90 0.74 0.02 -0.08 1.46 0.99 1.60 1.65 0.69 0.77 1.69 1.11 0.90 0.46 2.60 1.62
2492 || orf19.1805 || PEX14 || || Ortholog(s) have peroxisome matrix targeting signal-1 binding, peroxisome matrix targeting signal-2 binding, protein binding, bridging activity || 1 0.50 0.38 -0.32 -0.01 0.66 0.46 0.70 0.70 0.43 0.61 0.94 0.98 0.98 0.63 1.33 0.99
2493 || orf19.7201 || SLA2 || || Actin binding protein with roles in growth control and morphogenesis; required for alkaline pH-induced hyphal formation; localized to actin patches; rat catheter biofilm repressed || 1 0.57 0.49 -0.11 -0.06 1.07 0.48 0.67 0.89 0.32 -0.02 0.85 0.71 0.65 0.34 1.16 0.44
2494 || orf19.7201 || SLA2 || || Actin binding protein with roles in growth control and morphogenesis; required for alkaline pH-induced hyphal formation; localized to actin patches; rat catheter biofilm repressed || 1 0.50 0.39 0.06 -0.05 0.68 0.43 0.55 0.55 0.38 -0.07 0.63 0.39 0.56 0.30 0.72 0.50
2495 || orf19.6348 || || || Predicted cysteine proteinase domain; mutants are viable || 1 0.51 0.73 -0.40 -0.72 1.03 0.67 1.23 1.48 0.47 0.31 1.35 0.97 1.41 1.12 1.28 1.32
2496 || orf19.2650 || || || Protein of unknown function; rat catheter biofilm induced || 1 0.65 0.48 -0.44 -0.38 0.99 0.32 1.00 0.95 0.31 0.04 1.25 0.68 0.87 0.86 1.49 1.03
2497 || orf19.4348 || MED14 || || RNA polymerase II mediator complex subunit || 1 0.64 1.19 -0.52 -0.39 1.62 0.62 1.19 1.17 0.36 0.50 1.71 1.34 1.18 0.87 1.83 0.78
2498 || orf19.1595 || || || Ortholog(s) have Dsc E3 ubiquitin ligase complex, endoplasmic reticulum localization || 1 1.10 0.91 -0.32 -0.26 1.46 -0.03 1.29 1.10 0.61 0.52 1.08 1.33 0.83 1.69 1.06
2499 || orf19.4471 || || || Ortholog(s) have role in protein targeting to vacuole, re-entry into mitotic cell cycle after pheromone arrest and endoplasmic reticulum membrane localization || 1 0.65 0.48 -0.32 -0.13 1.11 0.21 0.99 0.90 0.41 0.65 1.22 0.88 0.56 0.45 1.06 0.92
2500 || orf19.4471 || || || Ortholog(s) have role in protein targeting to vacuole, re-entry into mitotic cell cycle after pheromone arrest and endoplasmic reticulum membrane localization || 1 0.49 0.36 -0.37 -0.31 1.03 0.02 0.61 0.41 0.29 0.13 0.83 0.47 0.61 0.38 0.75 0.79
2501 || orf19.6916 || || || Ortholog(s) have unfolded protein binding activity, role in mitochondrial proton-transporting ATP synthase complex assembly and mitochondrion localization || 1 0.42 0.42 -0.42 0.04 0.52 -0.04 1.18 0.93 0.35 0.55 1.24 0.57 0.50 0.32 1.20 0.56
2502 || orf19.4642 || || || Protein of unknown function; Hap43-induced gene || 1 0.40 0.43 -0.49 -0.25 0.34 -0.23 1.49 0.95 0.60 0.38 1.35 0.92 0.94 0.96 1.37 0.49
2503 || orf19.7047 || RTF1 || || Putative RNA polymerase II-associated Paf1 complex subunit; induced during the mating process || 1 0.54 0.47 -0.63 -0.55 0.40 -0.21 0.79 0.92 0.03 0.64 1.12 1.07 0.68 0.76 1.28 0.48
2504 || orf19.7047 || RTF1 || || Putative RNA polymerase II-associated Paf1 complex subunit; induced during the mating process || 1 0.47 0.59 -0.23 -0.15 0.47 -0.17 0.60 0.75 0.20 0.74 0.98 0.80 0.57 0.49 1.02 0.28
2505 || orf19.4751 || || || Ortholog(s) have structural constituent of ribosome activity and mitochondrial small ribosomal subunit localization || 1 0.59 0.41 -0.54 -0.48 0.46 -0.04 0.98 1.21 0.42 1.10 0.97 0.94 0.94 0.36 1.40 0.24
2506 || orf19.4670 || CAS5 || || Transcription factor; cell wall damage response; required for adherence, response/resistance to caspofungin; repressed in core stress response; mutants have reduced CFU in mice, hyphal defect in C. elegans infection; Spider biofilm induced || 1 0.40 0.59 -0.24 -0.12 0.28 0.02 1.16 1.38 0.56 0.84 1.22 0.81 1.21 0.31 1.58 0.69
2507 || orf19.6909 || || || Ortholog(s) have TFIIH-class transcription factor binding, TFIIH-class transcription factor recruiting transcription factor activity || 1 0.44 0.41 -0.28 -0.60 0.61 0.05 1.13 2.05 0.94 1.00 1.53 1.02 1.07 0.55 1.39 0.92
2508 || orf19.6916 || || || Ortholog(s) have unfolded protein binding activity, role in mitochondrial proton-transporting ATP synthase complex assembly and mitochondrion localization || 1 0.58 0.34 -0.37 -0.53 0.44 0.18 1.25 1.03 0.27 0.68 0.83 0.86 0.68 0.41 1.06 0.67
2509 || orf19.1755 || SET2 || || Ortholog(s) have histone methyltransferase activity (H3-K36 specific) activity || 1 0.35 0.52 -0.36 -0.61 0.71 0.32 1.25 1.12 0.68 0.81 1.24 1.11 1.07 0.68 1.53 0.73
2510 || orf19.5058 || SMI1 || || Cell wall biosynthesis protein; Hap43, caspofungin-repressed; Cyr1-induced in hyphal cells; reduced biofilm cell wall glucan in mutant; possibly essential (UAU1 method); flow model biofilm induced || 1 0.29 0.28 -0.65 -0.78 0.91 0.10 1.26 1.07 0.50 0.63 1.39 0.76 0.78 0.63 1.11 0.91
2511 || orf19.1755 || SET2 || || Ortholog(s) have histone methyltransferase activity (H3-K36 specific) activity || 1 0.28 0.18 -0.75 -0.93 0.77 -0.03 1.07 0.87 0.33 0.55 1.07 0.73 0.77 0.40 1.26 0.53
2512 || orf19.947 || MRP17 || || Predicted mitochondrial ribosomal protein || 1 0.31 0.09 -1.03 -0.99 0.96 0.17 1.25 1.33 0.51 1.32 1.67 1.09 1.36 0.63 1.56 0.47
2513 || orf19.947 || MRP17 || || Predicted mitochondrial ribosomal protein || 1 -0.03 0.05 -0.40 -0.70 1.06 0.28 1.88 1.87 0.64 1.46 1.99 1.37 1.71 0.75 2.22 0.64
2514 || orf19.6419.1 || || || Ortholog of C. parapsilosis CDC317 : CPAR2_205710, Candida tenuis NRRL Y-1498 : CANTEDRAFT_117073, Lodderomyces elongisporus NRLL YB-4239 : LELG_02945 and Debaryomyces hansenii CBS767 : DEHA2A11462g || 1 0.40 0.30 -0.72 -0.35 1.51 0.45 1.74 1.53 0.75 1.33 2.00 1.22 1.40 0.92 1.89 0.21
2515 || orf19.2369 || || || Ortholog(s) have ATP binding, DNA replication origin binding activity || 1 0.33 -0.03 -0.39 -0.06 0.71 0.10 0.83 0.99 0.46 0.42 1.47 0.56 0.96 0.65 0.95 0.58
2516 || orf19.6798 || SSN6 || || Functional homolog of S. cerevisiae Cyc8/Ssn6; hyphal growth regulator; repressed during hyphal growth; Ssn6 and Tup1 regulate distinct sets of genes; overexpression or mutation causes avirulence in mouse IV infection; TPR motifs || 1 0.23 0.15 -0.68 -0.07 0.79 0.59 1.23 1.10 0.72 0.34 1.49 0.77 1.30 0.83 1.52 0.69
2517 || orf19.3449 || || || Ortholog(s) have ubiquitin-protein ligase activity, role in histone catabolic process, histone ubiquitination and cytoplasm, ribosome localization || 1 0.44 0.48 -0.60 -0.32 0.88 0.95 1.29 1.51 0.68 0.92 2.14 1.50 1.72 1.12 1.68 0.85
2518 || orf19.4388 || || || Protein with a histone fold domain; similar to TAFII47 proteins from S. cerevisiae, Danio rerio, Drosophila melanogaster, human, and mouse || 1 0.23 0.02 -0.23 -0.29 0.51 0.45 0.97 1.06 0.22 0.59 1.45 0.86 0.65 0.70 1.31 0.74
2519 || orf19.7548 || MED21 || || Ortholog(s) have RNA polymerase II repressing transcription factor binding, RNA polymerase II transcription coactivator activity, RNA polymerase II transcription corepressor activity || 1 -0.12 0.28 -0.08 -0.30 0.70 0.09 1.38 1.11 0.57 0.86 1.28 0.94 0.75 0.81 1.31 1.04
2520 || orf19.6345 || RPG1A || || Putative translation initiation factor; mutation confers hypersensitivity to roridin A and verrucarin A; repressed upon phagocytosis by murine macrophage; Spider biofilm repressed || 1 0.22 0.32 -0.30 -0.31 0.74 0.27 1.33 1.57 0.78 1.50 1.62 1.21 1.10 1.34 1.16 0.97
2521 || orf19.6916 || || || Ortholog(s) have unfolded protein binding activity, role in mitochondrial proton-transporting ATP synthase complex assembly and mitochondrion localization || 1 0.33 0.22 -0.36 -0.35 0.40 -0.17 0.87 1.09 0.47 0.73 0.97 0.90 0.53 0.80 0.85 0.56
2522 || orf19.4503 || || || Similar to HMG-box variant of S. pombe; Spider biofilm repressed || 1 0.11 0.04 -1.09 -0.84 1.08 -0.18 1.66 1.94 0.82 1.01 2.09 1.06 1.57 1.85 1.60 1.08
2523 || orf19.6587 || GIR2 || || Ortholog of S. cerevisiae Gir2; transposon mutation affects filamentous growth || 1 0.05 0.27 -0.41 -0.51 0.87 -0.04 1.52 0.94 1.06 1.03 1.39 0.85 1.53 1.23 1.32 0.99
2524 || orf19.2961 || || || Putative transcription factor with zinc finger DNA-binding motif || 1 0.45 0.15 -0.17 -0.43 0.49 -0.16 0.50 0.73 0.36 0.54 0.83 0.65 0.86 0.57 0.86 0.45
2525 || orf19.7492 || SWC4 || || Subunit of the NuA4 histone acetyltransferase complex || 1 0.29 0.16 -0.37 -0.26 0.38 -0.09 0.71 0.78 0.30 0.35 0.92 0.33 0.77 0.42 0.45 0.44
2526 || orf19.5967 || FGR44 || || Protein lacking an ortholog in S. cerevisiae; transposon mutation affects filamentous growth || 1 0.28 0.63 -0.28 -0.17 0.73 0.17 1.14 1.12 0.45 0.85 1.18 0.62 1.54 0.59 1.24 0.18
2527 || orf19.4503 || || || Similar to HMG-box variant of S. pombe; Spider biofilm repressed || 1 0.62 0.92 0.02 -0.09 1.27 0.08 1.71 1.70 1.20 1.14 2.16 0.85 1.96 1.12 1.51 0.65
2528 || orf19.961.2 || || || Ortholog(s) have mitochondrion, nucleus localization || 1 0.38 0.59 -0.12 0.10 0.33 -0.04 0.96 1.65 0.85 0.85 1.64 0.85 0.72 0.56 0.66 0.12
2529 || orf19.4727 || || || Ortholog(s) have succinate dehydrogenase (ubiquinone) activity || 1 0.42 0.68 -0.10 -0.16 0.42 -0.18 0.97 1.11 0.68 0.95 1.61 0.86 0.56 0.85 0.85 0.02
2530 || orf19.3899 || SDC1 || || Putative COMPASS/SET1C histone methyltransferase complex subunit || 1 0.65 0.80 0.32 0.11 0.97 -0.02 1.10 1.48 0.78 1.12 1.78 0.82 0.99 1.10 1.08 0.23
2531 || orf19.4025 || PRE1 || || Putative beta 4 subunit of the 20S proteasome; Rim101-induced at acid pH; flucytosine induced; amphotericin B repressed || 1 0.57 0.67 -0.04 0.05 0.58 -0.33 0.77 1.03 0.41 0.75 1.04 0.59 0.78 0.50 1.01 -0.07
2532 || orf19.760 || || || Ortholog(s) have role in ribosome biogenesis and mitochondrion localization || 1 0.68 0.79 -0.73 -0.69 1.24 -0.08 1.89 2.41 0.78 1.46 1.85 0.30 1.19 0.66 1.90 0.19
2533 || orf19.1109 || || || Ortholog of C. dubliniensis CD36 : Cd36_53580, C. parapsilosis CDC317 : CPAR2_303030, Debaryomyces hansenii CBS767 : DEHA2G07766g and Pichia stipitis Pignal : psti_CGOB_00176 || 1 0.73 0.84 -0.43 -0.59 1.13 0.04 1.92 2.16 1.03 1.15 1.78 0.54 1.26 0.78 1.21 0.03
2534 || orf19.3297 || || || Ortholog(s) have structural constituent of ribosome activity and mitochondrial small ribosomal subunit localization || 1 1.07 1.13 -0.13 -0.46 1.44 0.54 2.00 2.49 1.09 1.15 2.28 0.48 1.33 0.39 1.60 0.18
2535 || orf19.3297 || || || Ortholog(s) have structural constituent of ribosome activity and mitochondrial small ribosomal subunit localization || 1 0.89 0.74 -0.42 -0.44 1.48 0.59 1.84 1.93 1.00 1.08 2.18 0.83 0.94 0.81 1.33 0.28
2536 || orf19.3297 || || || Ortholog(s) have structural constituent of ribosome activity and mitochondrial small ribosomal subunit localization || 1 0.65 0.68 -0.42 -0.43 1.46 0.62 1.92 2.23 1.04 1.29 2.40 0.87 0.92 0.75 1.54 0.67
2537 || orf19.3297 || || || Ortholog(s) have structural constituent of ribosome activity and mitochondrial small ribosomal subunit localization || 1 0.43 0.47 -0.67 -0.49 1.19 0.60 1.79 2.11 1.22 1.22 1.96 0.84 0.70 0.89 1.43 0.61
2538 || orf19.4676 || || || Protein with homology to mitochondrial intermembrane space proteins; regulated by Sef1p-, Sfu1p-, and Hap43p || 1 0.79 0.73 0.04 0.04 0.95 0.36 1.37 1.91 1.07 0.65 1.70 0.93 0.78 0.79 1.29 0.40
2539 || orf19.4727 || || || Ortholog(s) have succinate dehydrogenase (ubiquinone) activity || 1 0.83 0.91 -0.37 0.15 0.76 0.25 1.32 1.47 0.91 0.85 1.68 0.79 0.64 0.46 1.03 0.47
2540 || orf19.4727 || || || Ortholog(s) have succinate dehydrogenase (ubiquinone) activity || 1 0.63 0.80 0.01 0.20 0.69 0.00 0.91 1.24 0.62 0.66 1.36 0.52 0.81 0.38 0.94 0.08
2541 || orf19.5161 || || || Ortholog(s) have structural constituent of ribosome activity and mitochondrial large ribosomal subunit localization || 1 0.45 0.71 -0.08 -0.05 0.80 -0.09 1.21 1.53 0.78 0.76 1.45 0.67 0.51 0.14 1.10 0.32
2542 || orf19.4676 || || || Protein with homology to mitochondrial intermembrane space proteins; regulated by Sef1p-, Sfu1p-, and Hap43p || 1 0.44 0.52 -0.26 -0.40 0.71 -0.04 1.55 1.80 0.92 0.88 1.88 1.12 0.70 0.94 1.11 0.39
2543 || orf19.3297 || || || Ortholog(s) have structural constituent of ribosome activity and mitochondrial small ribosomal subunit localization || 1 0.24 0.51 -0.53 -0.63 0.94 0.50 2.04 2.26 0.97 1.14 1.76 0.78 0.40 0.46 1.53 0.60
2544 || orf19.1111 || || || Ortholog(s) have chromatin binding, protein complex scaffold activity and role in RNA polymerase II transcriptional preinitiation complex assembly, histone acetylation || 1 0.03 0.56 -0.06 0.17 0.40 -0.06 1.08 1.36 0.61 0.93 1.27 0.57 0.58 0.69 1.22 0.51
2545 || orf19.6362 || SPA2 || || Protein involved in cell polarity, Spitzenkorper formation; required for mouse virulence; localizes to hyphal tip; cell-cycle regulated localization in yeast-form cells; functional domains conserved with S. cerevisiae ; Hap43p-induced gene || 1 0.55 0.45 -0.17 -0.09 0.60 0.24 0.65 1.11 0.33 0.75 1.27 0.45 0.81 1.17 0.87 0.38
2546 || orf19.3474 || IPL1 || || Putative Aurora kinase; Hap43-induced; induced during planktonic growth; possibly an essential gene, disruptants not obtained by UAU1 method || 1 0.84 0.52 -0.31 0.09 0.82 0.40 1.03 1.12 -0.03 0.57 1.74 0.51 0.65 0.85 0.76 0.51
2547 || orf19.7667 || IAH1 || || Protein similar to S. cerevisiae Iah1p, which is involved in acetate metabolism; mutation confers hypersensitivity to tunicamycin; transposon mutation affects filamentous growth || 1 0.51 0.22 -0.14 -0.06 0.58 0.09 0.70 1.06 0.23 0.35 0.76 0.47 0.41 0.04 0.73 0.24
2548 || orf19.3777 || IMG2 || || Mitochondrial ribosomal protein of the large subunit; rat catheter biofilm induced || 1 0.97 1.09 -1.08 -1.10 1.71 0.44 2.33 1.84 1.06 1.40 2.25 0.93 1.12 0.11 2.21 0.24
2549 || orf19.6378 || TRM9 || || Putative tRNA methyltransferase; repressed during the mating process || 1 0.18 1.02 -0.26 -0.46 1.16 0.89 1.75 1.44 0.62 1.02 1.64 0.28 1.00 0.54 1.25 0.21
2550 || orf19.760 || || || Ortholog(s) have role in ribosome biogenesis and mitochondrion localization || 1 1.03 0.58 -0.49 -0.31 1.41 -0.19 1.52 1.54 1.15 1.52 1.59 0.37 1.39 0.59 1.23 0.23
2551 || orf19.2650.1 || || || Mitochondrial ribosomal protein of the small subunit; Spider biofilm repressed || 1 0.50 0.93 -0.44 -0.20 1.04 -0.36 1.55 1.92 1.00 1.69 1.39 0.70 1.11 0.63 1.48 -0.17
2552 || orf19.2650.1 || || || Mitochondrial ribosomal protein of the small subunit; Spider biofilm repressed || 1 0.79 0.78 -0.64 -0.26 0.70 -0.51 1.65 1.85 0.90 1.50 0.92 0.28 1.74 0.64 1.49 0.12
2553 || orf19.5967 || FGR44 || || Protein lacking an ortholog in S. cerevisiae; transposon mutation affects filamentous growth || 1 0.44 0.57 -0.67 -0.08 0.57 0.10 0.98 1.33 0.80 0.99 0.98 0.21 1.74 0.33 1.35 0.54
2554 || orf19.4670 || CAS5 || || Transcription factor; cell wall damage response; required for adherence, response/resistance to caspofungin; repressed in core stress response; mutants have reduced CFU in mice, hyphal defect in C. elegans infection; Spider biofilm induced || 1 0.97 0.47 -0.30 0.01 0.60 -0.73 1.13 1.39 0.96 0.81 1.44 0.78 1.13 0.81 2.36 0.72
2555 || orf19.1359 || || || Ortholog(s) have protein complex binding activity, role in ER-associated ubiquitin-dependent protein catabolic process, sporulation resulting in formation of a cellular spore and cytoplasm, extrinsic to membrane, nucleus localization || 1 0.62 0.74 -0.16 -0.11 0.39 -0.32 0.92 0.91 0.80 0.88 0.58 0.86 0.62 0.56 1.17 0.84
2556 || orf19.4642 || || || Protein of unknown function; Hap43-induced gene || 1 0.63 0.53 0.05 -0.22 0.28 -0.15 0.59 0.74 0.22 0.34 0.85 0.85 0.69 0.45 0.81 0.61
2557 || orf19.6027 || || || Ortholog of C. dubliniensis CD36 : Cd36_00740, C. parapsilosis CDC317 : CPAR2_110170, Candida tenuis NRRL Y-1498 : CANTEDRAFT_133175 and Debaryomyces hansenii CBS767 : DEHA2D09724g || 1 0.67 1.13 -0.64 -0.58 0.67 -0.03 0.75 1.08 0.60 0.69 1.17 1.38 1.08 1.17 1.08 1.03
2558 || orf19.1711 || END3 || || Regulated by Gcn4p; induced in response to amino acid starvation (3-aminotriazole treatment) || 1 0.75 0.49 -0.23 -0.43 0.32 0.09 0.86 0.49 0.21 0.40 0.87 0.79 0.74 1.07 1.02 1.00
2559 || orf19.6893 || || || Ortholog(s) have role in ER to Golgi vesicle-mediated transport, cellular response to cadmium ion, detoxification of cadmium ion || 1 0.46 0.56 -0.12 -0.48 0.43 -0.25 0.99 0.69 0.02 0.58 1.55 1.04 0.73 0.21 1.00 0.25
2560 || orf19.6893 || || || Ortholog(s) have role in ER to Golgi vesicle-mediated transport, cellular response to cadmium ion, detoxification of cadmium ion || 1 0.43 0.42 -0.19 -0.22 0.37 0.21 0.62 0.58 -0.05 0.53 1.61 1.25 0.35 0.49 1.14 0.72
2561 || orf19.2002 || || || Ortholog(s) have structural constituent of nuclear pore activity and role in nuclear pore organization, poly(A)+ mRNA export from nucleus, protein import into nucleus, ribosomal large subunit export from nucleus || 1 0.38 0.14 -0.36 -0.23 0.35 0.49 0.48 0.49 0.07 0.31 1.03 0.56 0.30 0.31 0.44 0.39
2562 || orf19.1885 || TAF4 || || Putative TFIID subunit; mutation confers hypersensitivity to toxic ergosterol analog || 1 0.54 0.52 -0.18 -0.32 0.34 0.35 0.40 0.59 0.02 0.25 0.93 0.51 0.07 0.23 0.49 0.59
2563 || orf19.193 || || || Ortholog of C. dubliniensis CD36 : Cd36_19310, C. parapsilosis CDC317 : CPAR2_209710, Candida tenuis NRRL Y-1498 : CANTEDRAFT_113479 and Debaryomyces hansenii CBS767 : DEHA2C15114g || 1 0.57 0.36 -0.47 -0.24 0.44 0.10 0.51 0.72 0.04 0.09 1.22 0.07 0.25 0.64 0.46 0.43
2564 || orf19.7043.1 || ACB1 || || Protein similar to a region of acyl-coenzyme-A-binding protein; amphotericin B repressed; regulated by Nrg1, Tup1; Hap43-induced || 1 1.15 1.18 -0.52 -0.89 1.41 0.22 1.06 1.72 -0.12 0.09 2.99 1.32 0.89 0.85 1.18 1.34
2565 || orf19.7043.1 || ACB1 || || Protein similar to a region of acyl-coenzyme-A-binding protein; amphotericin B repressed; regulated by Nrg1, Tup1; Hap43-induced || 1 1.28 1.37 -0.52 -0.95 1.53 -0.05 1.22 1.84 -0.27 0.05 3.17 1.01 1.15 0.68 1.30 0.58
2566 || orf19.5397 || || || Putative conserved oligomeric Golgi complex subunit; decreased transcription is observed upon fluphenazine treatment || 1 0.52 0.58 -0.29 -0.51 0.82 -0.13 0.35 0.54 -0.31 -0.03 1.41 0.39 0.28 0.18 0.57 0.51
2567 || orf19.6135 || || || Ortholog of C. dubliniensis CD36 : Cd36_32970, C. parapsilosis CDC317 : CPAR2_701710, Candida tenuis NRRL Y-1498 : CANTEDRAFT_106599 and Debaryomyces hansenii CBS767 : DEHA2E04488g || 1 0.43 0.24 -0.25 -0.38 0.47 0.12 0.41 1.32 0.24 0.18 1.20 0.34 0.41 0.04 0.45 0.46
2568 || orf19.4734 || || || Protein of unknown function; Hap43-repressed || 1 0.32 0.25 -0.88 -0.57 0.68 0.18 0.67 0.99 0.26 -0.35 1.52 0.47 0.58 0.31 0.58 1.00
2569 || orf19.3762 || || || Ortholog of C. dubliniensis CD36 : Cd36_11720, C. parapsilosis CDC317 : CPAR2_201890, Candida tenuis NRRL Y-1498 : CANTEDRAFT_91948 and Debaryomyces hansenii CBS767 : DEHA2E16786g || 1 1.09 0.85 -0.35 -0.52 0.68 -0.49 1.09 1.72 0.57 0.52 1.38 0.48 0.44 0.42 0.64 0.90
2570 || orf19.3574 || MDJ2 || || Predicted component of the mitochondrial import motor; involved in protein import into mitochondrial matrix; early-stage flow model biofilm induced || 1 0.89 0.57 -0.71 -0.67 0.52 0.03 1.12 1.50 0.51 0.09 0.77 -0.05 0.37 0.65 0.34 0.77
2571 || orf19.925 || SAM51 || || Component of the SAM complex involved in mitochondrial protein import, involved in beta-barrel protein assembly; member of the Omp85 protein family || 1 0.47 0.35 -0.65 -0.49 0.48 -0.24 0.91 1.29 0.42 0.37 0.60 0.05 0.63 0.42 0.71 0.27
2572 || orf19.6436 || || || Ortholog of C. dubliniensis CD36 : Cd36_34210, C. parapsilosis CDC317 : CPAR2_205590, Candida tenuis NRRL Y-1498 : cten_CGOB_00133 and Debaryomyces hansenii CBS767 : DEHA2E02178g || 1 0.32 0.27 -0.31 -0.27 0.03 -0.42 0.70 0.70 0.05 0.64 0.62 -0.02 0.17 0.57 0.36 0.32
2573 || orf19.5875 || VAM3 || || Predicted target membrane receptor (t-SNARE) involved in vacuolar transport, endocytosis, and secretion; required for biofilm formation in RPMI-1640 and for virulence; rat catheter biofilm repressed || 1 0.37 0.81 -0.37 -0.37 0.08 -0.71 0.74 1.06 0.39 0.75 0.85 0.43 0.52 0.99 0.68 0.37
2574 || orf19.4430 || || || Ortholog(s) have ubiquitin binding activity, role in proteasome-mediated ubiquitin-dependent protein catabolic process and cytoplasm, nucleus localization || 1 0.59 0.45 -0.51 -0.39 -0.04 -0.65 0.84 1.13 0.48 0.47 0.82 0.25 0.27 0.39 0.89 0.73
2575 || orf19.3235 || || || Putative F-actin capping protein subunit alpha; possibly an essential gene, disruptants not obtained by UAU1 method || 1 0.44 0.30 -0.65 -0.73 -0.34 -0.71 0.99 1.09 0.32 0.32 1.22 0.32 0.09 0.82 0.60 0.44
2576 || orf19.2542 || || || Ortholog(s) have nucleus localization || 1 0.90 0.29 -0.24 -0.31 0.65 0.80 1.60 1.68 -0.04 0.42 1.38 0.34 0.96 0.37 1.67 0.75
2577 || orf19.5201 || || || Ortholog(s) have structural constituent of ribosome activity and mitochondrial small ribosomal subunit localization || 1 0.25 0.21 -0.59 -0.75 0.45 -0.07 0.63 1.02 0.12 0.66 0.70 0.12 0.51 0.06 0.85 0.01
2578 || orf19.1505 || || || Ortholog(s) have cytoplasm localization || 1 0.22 0.21 -1.03 -0.86 1.00 0.43 1.17 2.10 1.23 1.00 2.05 0.53 0.28 -0.15 1.55 0.14
2579 || orf19.6283 || || || Ortholog(s) have mitochondrion localization || 1 0.33 0.09 -0.64 -0.16 0.52 0.07 0.23 0.70 0.40 0.64 0.64 0.42 0.16 0.34 0.52 0.19
2580 || orf19.2435 || MSI3 || || Essential HSP70 family protein; required for fluconazole resistance and calcineurin-dependent transcription; interacts with Cgr1; transcript regulated by iron; rat catheter biofilm induced; farnesol repressed in biofilm; sumoylation target || 1 0.72 0.50 -0.68 -0.52 1.64 0.65 1.19 1.63 0.47 1.19 1.37 0.58 0.19 0.12 0.94 0.44
2581 || orf19.3396 || HCH1 || || Ortholog of S. cerevisiae Hch1, a regulator of heat shock protein Hsp90; regulated by Gcn4; induced in response to amino acid starvation (3-aminotriazole treatment); mutants are viable || 1 0.49 0.44 -0.71 -0.68 1.42 0.88 0.94 1.52 0.35 0.70 1.79 0.67 0.44 0.57 0.74 0.52
2582 || orf19.2435 || MSI3 || || Essential HSP70 family protein; required for fluconazole resistance and calcineurin-dependent transcription; interacts with Cgr1; transcript regulated by iron; rat catheter biofilm induced; farnesol repressed in biofilm; sumoylation target || 1 0.16 0.16 -1.03 -0.90 1.07 0.40 0.76 1.07 0.05 0.75 1.12 0.34 -0.00 0.49 0.69 0.39
2583 || orf19.4093 || PES1 || || Pescadillo homolog required for yeast cell growth, lateral yeast growth on filamentous cells and virulence in mice; hyphal cells grow normally in mutant; mutation confers hypersensitivity to 5-fluorocytosine, 5-fluorouracil, tubercidin || 1 0.66 0.70 -1.17 -0.68 1.44 1.11 1.10 1.47 -0.09 1.73 1.65 -0.12 0.36 1.07 0.54 0.33
2584 || orf19.5835 || || || Ortholog(s) have role in rRNA processing, ribosomal small subunit assembly and CURI complex, UTP-C complex, cytosol localization || 1 0.11 -0.01 -0.19 -0.67 0.20 0.27 0.77 0.76 0.14 1.00 1.33 0.65 0.62 0.54 0.54 -0.09
2585 || orf19.3686 || || || Ortholog(s) have protein domain specific binding activity, role in mitochondrial proton-transporting ATP synthase complex assembly and mitochondrion localization || 1 0.34 0.39 -0.44 -0.60 0.30 -0.18 0.61 0.68 -0.07 0.61 0.66 0.68 0.32 0.08 0.35 0.34
2586 || orf19.2389 || || || Ortholog(s) have DNA replication origin binding, single-stranded DNA binding activity || 1 0.19 0.31 -0.71 -0.42 0.60 -0.24 1.07 0.99 -0.05 1.10 0.86 0.06 0.90 0.83 0.08 0.40
2587 || orf19.2389 || || || Ortholog(s) have DNA replication origin binding, single-stranded DNA binding activity || 1 0.18 -0.03 -0.12 -0.08 0.35 -0.36 0.56 0.97 0.36 0.77 0.53 0.52 0.54 0.91 0.42 0.26
2588 || orf19.7613 || HCR1 || || Putative translation initiation factor; repressed upon phagocytosis by murine macrophage; Spider biofilm repressed || 1 -0.14 -0.04 -0.19 -0.18 0.20 -0.22 0.39 0.68 0.31 0.71 0.54 0.32 0.26 0.54 -0.08 0.20
2589 || orf19.643 || || || Ortholog(s) have role in apoptotic process, mitotic spindle elongation, sister chromatid biorientation, spindle assembly checkpoint || 1 0.06 0.08 -0.24 0.05 0.29 -0.13 0.58 1.09 0.57 1.06 0.55 0.55 0.77 0.25 0.07 0.43
2590 || orf19.6314 || RPB8 || || Putative subunit of RNA polymerases I, II, and III; regulated by Gcn4p; repressed in response to amino acid starvation (3-aminotriazole treatment); heterozygous null mutant exhibits resistance to parnafungin || 1 0.52 0.41 -0.48 -0.16 0.31 -0.34 0.83 1.18 -0.00 0.78 0.99 0.27 0.77 -0.09 0.58 -0.32
2591 || orf19.6170 || || || Ortholog(s) have microtubule binding, protein heterodimerization activity, protein homodimerization activity || 1 0.52 0.61 -0.35 0.15 0.56 -0.56 0.56 0.94 0.30 0.40 0.72 -0.09 0.42 0.24 0.50
2592 || orf19.6362 || SPA2 || || Protein involved in cell polarity, Spitzenkorper formation; required for mouse virulence; localizes to hyphal tip; cell-cycle regulated localization in yeast-form cells; functional domains conserved with S. cerevisiae ; Hap43p-induced gene || 1 0.39 0.47 -0.60 -0.52 1.00 -0.27 0.88 1.06 -0.28 0.24 1.12 -0.30 0.95 0.52 0.74 -0.12
2593 || orf19.6598 || WAL1 || || Protein required for hyphal growth and for wild-type cell morphology, polarized budding, endocytosis, vacuole morphology; similar to Wiskott-Aldrich syndrome protein; localizes to cortical actin patches and hyphal tips || 1 0.02 -0.01 -0.39 -0.16 0.43 -0.06 0.71 0.56 0.35 0.19 0.67 -0.10 0.63 0.39 0.74 -0.10
2594 || orf19.738 || MYO5 || || Class I myosin; nonessential; role in cortical actin patch polarity and polar budding; required for hyphal growth, white-opaque switch; regulatory phosphorylation on S366; downregulated on adherence to polystyrene || 1 0.30 0.43 -0.05 0.09 0.65 0.20 0.67 0.44 0.50 -0.12 0.55 -0.15 0.64 0.13 0.72 -0.00
2595 || orf19.1468 || CDC55 || || Ortholog(s) have protein phosphatase type 2A regulator activity, protein serine/threonine phosphatase activity || 1 0.29 0.59 0.02 -0.15 0.53 -0.33 0.52 0.55 0.34 -0.13 0.84 0.18 0.80 0.04 0.66 -0.14
2596 || orf19.7506 || || || Ortholog(s) have ATPase activity, DNA binding, nucleosome binding activity, role in chromatin remodeling and Isw1 complex localization || 1 0.29 0.04 0.06 0.09 0.42 -0.28 0.77 1.02 0.28 -0.02 1.29 0.16 0.65 0.29 0.06 0.29
2597 || orf19.4596 || || || Protein of unknown function; Spider biofilm induced || 1 0.23 0.39 0.10 -0.31 0.58 -0.63 1.31 0.62 0.32 -0.08 1.23 -0.03 0.62 0.12 0.62 0.67
2598 || orf19.7345 || || || Ortholog(s) have ATP binding activity and cytosol, nucleus localization || 1 0.28 -0.06 -0.28 -0.37 0.10 -0.59 0.90 0.70 0.56 0.25 1.15 0.05 0.59 0.36 0.69 0.41
2599 || orf19.132 || || || Ortholog(s) have role in histone deacetylation, negative regulation of chromatin silencing at telomere, negative regulation of meiosis, positive regulation of stress-activated MAPK cascade || 1 0.12 0.06 -0.23 -0.51 -0.28 -0.22 0.57 0.25 0.31 -0.01 0.51 0.35 0.50 0.33 0.22 0.68
2600 || orf19.4982 || || || Has domain(s) with predicted role in lipid metabolic process || 1 -0.10 0.00 -0.34 -0.95 -0.21 -0.14 0.78 0.51 0.42 -0.42 1.09 0.66 0.71 0.40 0.33 1.24
2601 || orf19.835 || || || Ortholog(s) have role in nucleosome mobilization and Ino80 complex, cytosol localization || 1 0.14 0.37 -0.12 -0.54 -0.01 0.02 0.31 0.43 0.23 -0.38 0.55 0.50 0.14 0.04 0.20 0.69
2602 || orf19.5320 || NCE4 || || Putative RecQ-mediated genome instability protein; Hap43-repressed gene; periodic mRNA expression, peak at cell-cycle G2/M phase; flow model biofilm induced || 1 0.48 0.39 -0.99 -1.11 0.08 -0.22 1.13 0.95 0.29 0.00 1.32 0.68 0.13 0.32 0.35 1.17
2603 || orf19.5320 || NCE4 || || Putative RecQ-mediated genome instability protein; Hap43-repressed gene; periodic mRNA expression, peak at cell-cycle G2/M phase; flow model biofilm induced || 1 0.23 0.03 -0.66 -0.69 0.51 -0.02 0.50 0.71 0.40 -0.24 0.87 0.65 0.06 0.44 -0.06 1.13
2604 || orf19.2822 || || || Essential component of the conserved oligomeric Golgi complex; role in fusion of transport vesicles to Golgi compartments; rat catheter biofilm repressed || 1 0.09 -0.15 -0.56 -0.98 0.21 -0.03 0.30 0.51 0.39 0.09 0.55 0.53 0.50 0.30 -0.25 0.69
2605 || orf19.839 || || || Putative endoribonuclease; induced by nitric oxide independent of Yhb1p; mutation confers hypersensitivity to aureobasidin A || 1 0.01 0.27 -0.44 -0.54 0.62 -0.32 0.52 0.33 0.18 -0.05 0.98 0.45 0.67 0.17 0.14 0.40
2606 || orf19.1507 || AMN1 || || Putative negative regulator of exit from mitosis; Plc1-regulated; rat catheter biofilm induced || 1 0.41 0.48 -0.90 -1.13 1.23 -0.17 0.97 1.01 0.26 0.10 1.23 0.49 1.36 0.72 0.04 -0.08
2607 || orf19.4686 || || || Ortholog of S. cerevisiae : ESL1, C. dubliniensis CD36 : Cd36_41030, C. parapsilosis CDC317 : CPAR2_401340, Candida tenuis NRRL Y-1498 : CANTEDRAFT_104645 and Debaryomyces hansenii CBS767 : DEHA2E18766g || 1 0.44 0.39 -0.51 -0.32 0.48 -0.17 0.64 0.55 0.49 -0.09 0.51 0.41 0.52 0.09 0.23 0.06
2608 || orf19.550 || PDX3 || || Pyridoxamine-phosphate oxidase; transcript regulated by yeast-hypha switch and by Nrg1, Mig1, Tup1; Hap43, caspofungin repressed; present in exponential and stationary phase yeast cultures || 1 0.82 0.73 -0.26 -0.89 0.52 0.49 1.16 1.06 0.63 -0.87 1.07 0.54 0.93 0.38 0.56 0.76
2609 || orf19.550 || PDX3 || || Pyridoxamine-phosphate oxidase; transcript regulated by yeast-hypha switch and by Nrg1, Mig1, Tup1; Hap43, caspofungin repressed; present in exponential and stationary phase yeast cultures || 1 0.57 0.54 -0.47 -1.08 0.42 0.47 1.06 1.01 0.73 -0.73 1.00 0.67 0.98 0.51 0.96 0.95
2610 || orf19.2132 || || || Ortholog of C. dubliniensis CD36 : Cd36_65220, C. parapsilosis CDC317 : CPAR2_213740, Candida tenuis NRRL Y-1498 : CANTEDRAFT_92162 and Debaryomyces hansenii CBS767 : DEHA2A01056g || 1 0.11 0.30 -0.52 -0.85 0.18 0.13 1.06 0.89 0.70 -0.14 1.01 0.31 1.31 0.47 0.55 0.54
2611 || orf19.5297 || || || Ortholog(s) have phosphatidylinositol-3-phosphate binding, phosphatidylinositol-5-phosphate binding activity || 1 0.05 0.57 -0.73 -0.95 0.76 0.62 1.32 0.93 0.73 0.23 1.11 0.62 1.27 0.31 1.04 0.85
2612 || orf19.1474 || SLA1 || || Protein required for assembly of the cortical actin cytoskeleton; contains three SH3 domains; transcription is regulated by Nrg1 and Mig1; flow model biofilm repressed || 1 -0.11 -0.00 -0.52 -0.76 0.53 -0.01 0.68 0.46 0.14 -0.26 0.50 0.18 0.41 0.22 0.50 0.17
2613 || orf19.6348 || || || Predicted cysteine proteinase domain; mutants are viable || 1 -0.06 0.19 -1.05 -1.04 0.58 -0.10 0.59 0.64 0.03 -0.01 0.54 0.14 0.84 0.33 0.66 0.64
2614 || orf19.2132 || || || Ortholog of C. dubliniensis CD36 : Cd36_65220, C. parapsilosis CDC317 : CPAR2_213740, Candida tenuis NRRL Y-1498 : CANTEDRAFT_92162 and Debaryomyces hansenii CBS767 : DEHA2A01056g || 1 -0.01 -0.04 -1.46 -1.63 0.06 -0.31 1.48 1.21 0.66 -0.20 1.34 0.40 1.47 1.03 0.62 1.06
2615 || orf19.3698 || || || Protein of unknown function that may function in RNA processing; filament induced || 1 -0.24 0.01 -0.76 -1.07 0.14 -0.54 0.76 0.25 0.09 0.08 0.67 -0.32 0.98 0.44 0.60 0.24
2616 || orf19.194 || || || Ortholog of C. dubliniensis CD36 : Cd36_19300, C. parapsilosis CDC317 : CPAR2_209720, Candida tenuis NRRL Y-1498 : CANTEDRAFT_114035 and Debaryomyces hansenii CBS767 : DEHA2E10494g || 1 -0.01 0.10 -0.31 -0.33 0.34 -0.22 0.26 0.23 -0.25 0.08 0.96 0.47 0.82 0.45 0.36 0.46
2617 || orf19.4428 || || || Ortholog of C. dubliniensis CD36 : Cd36_06910, C. parapsilosis CDC317 : CPAR2_208560, Candida tenuis NRRL Y-1498 : CANTEDRAFT_95854 and Debaryomyces hansenii CBS767 : DEHA2F25982g || 1 0.13 0.30 -0.61 -1.00 -0.17 -0.68 0.42 0.50 0.22 0.65 1.38 1.20 1.45 0.99 0.95 0.64
2618 || orf19.826 || MED1 || || RNA polymerase II mediator complex subunit; RNA polymerase II transcription cofactor || 1 -0.17 0.14 -0.18 -0.44 0.19 -0.23 0.55 0.38 0.02 0.14 0.68 0.90 0.50 0.42 0.70 0.24
2619 || orf19.194 || || || Ortholog of C. dubliniensis CD36 : Cd36_19300, C. parapsilosis CDC317 : CPAR2_209720, Candida tenuis NRRL Y-1498 : CANTEDRAFT_114035 and Debaryomyces hansenii CBS767 : DEHA2E10494g || 1 -0.11 -0.25 -0.24 -0.63 0.46 -0.23 0.41 0.40 0.04 0.31 1.06 0.76 0.54 0.66 0.33 -0.13
2620 || orf19.2265 || || || Ortholog(s) have role in positive regulation of transcription from RNA polymerase II promoter in response to amino acid starvation and SWI/SNF complex, cytosol localization || 1 -0.20 0.15 -0.41 -0.41 -0.06 -0.25 0.21 0.37 0.08 0.31 0.73 0.40 0.29 0.37 0.02 -0.14
2621 || orf19.6008.4 || || || Ortholog(s) have mitochondrion localization || 1 -0.20 -0.40 -1.48 -0.59 -0.06 -0.62 1.03 1.52 0.81 0.79 0.98 0.37 0.25 0.28 0.29 -0.82
2622 || orf19.5698 || || || Putative mitochondrial ribosomal protein of the large subunit; transcript is upregulated in clinical isolates from HIV+ patients with oral candidiasis; Spider biofilm repressed || 1 -0.24 -0.17 -1.05 -0.95 0.13 -0.14 0.86 1.17 0.15 1.08 0.59 0.02 0.09 0.03 0.09 -0.21
2623 || orf19.5698 || || || Putative mitochondrial ribosomal protein of the large subunit; transcript is upregulated in clinical isolates from HIV+ patients with oral candidiasis; Spider biofilm repressed || 1 -0.24 -0.13 -0.81 -0.81 0.08 -0.31 0.67 1.00 0.31 1.14 0.58 -0.30 0.20 0.08 -0.16 -0.06
2624 || orf19.6891 || RFC1 || || Putative DNA replication factor C subunit; ortholog of S. cerviaie Rfc1; likely essential, based on an insertional mutagenesis strategy; rat catheter biofilm repressed || 1 -0.18 0.09 -0.59 -0.60 0.22 -0.40 0.40 0.46 0.24 0.36 0.38 -0.05 0.37 0.64 0.03 -0.13
2625 || orf19.2406 || || || Ortholog(s) have role in microautophagy, positive regulation of TOR signaling cascade, positive regulation of transcription from RNA polymerase II promoter || 1 0.05 -0.01 -0.39 -0.34 0.08 -0.17 0.28 0.35 -0.13 0.08 0.43 0.00 0.10 0.41 0.06 -0.04
2626 || orf19.6539 || || || Putative trancription modulator; RuvB-like protein family member; heterozygous null mutant displays sensitivity to virgineone || 1 -0.11 -0.14 -1.15 -1.14 0.31 -0.19 0.55 0.86 0.22 0.32 0.74 -0.11 0.03 0.44 0.05 0.41
2627 || orf19.4623 || || || Protein of unknown function; Spider biofilm repressed || 1 0.17 0.10 -0.36 -0.24 0.50 -0.47 0.49 0.79 -0.25 0.41 1.23 0.21 0.38 -0.03 0.88 -0.03
2628 || orf19.4623 || || || Protein of unknown function; Spider biofilm repressed || 1 0.14 -0.13 -0.62 -0.24 0.23 -0.37 0.21 0.57 -0.27 0.38 1.02 0.53 0.12 -0.14 0.83 0.14
2629 || orf19.6252 || || || Ortholog(s) have RNA polymerase II transcription factor binding transcription factor activity, core RNA polymerase II binding transcription factor activity || 1 -0.13 0.00 -0.59 -0.47 0.09 -0.51 0.41 0.57 -0.28 0.75 0.80 0.16 0.19 0.05 0.73 0.38
2630 || orf19.5771 || PBP2 || || Putative RNA binding protein; transcript regulated by Nrg1, Mig1, and Tup1 || 1 0.25 -0.02 -0.44 -0.53 0.26 -0.39 0.41 0.84 -0.18 0.50 0.71 0.30 0.11 0.26 0.44 0.48
2631 || orf19.3730 || || || Protein similar to S. cerevisiae Kre27p, which has a role in resistance to killer toxin; predicted Kex2p substrate || 1 0.05 0.22 -0.41 -0.50 0.24 -0.97 0.38 0.86 0.25 0.43 1.22 1.01 0.50 0.17 0.64 0.63
2632 || orf19.1406 || || || Ortholog(s) have DNA-directed DNA polymerase activity, role in error-free translesion synthesis, error-prone translesion synthesis and mitochondrion, nuclear chromatin, zeta DNA polymerase complex localization || 1 0.15 -0.04 -0.33 -0.23 0.71 -0.87 0.12 0.45 0.09 -0.02 0.89 0.48 0.51 -0.12 0.68 0.35
2633 || orf19.1759 || PHO23 || || Ortholog(s) have methylated histone residue binding activity || 1 0.06 0.26 -0.32 -0.37 0.43 -0.29 0.01 0.54 0.05 0.06 0.99 0.36 0.56 -0.01 0.49 0.48
2634 || orf19.6753 || || || Protein with a predicted RING-type zinc finger; possibly an essential gene, disruptants not obtained by UAU1 method || 1 0.13 0.14 -0.40 -0.30 0.43 -0.21 0.19 0.41 -0.01 -0.09 0.61 0.46 0.26 0.13 0.65 0.23
2635 || orf19.3467 || SEC27 || || Ortholog(s) have ubiquitin binding activity || 1 0.13 0.01 -0.07 -0.08 -0.12 -0.29 0.70 0.62 -0.09 0.36 0.94 0.88 0.41 0.81 0.61 1.08
2636 || orf19.6801 || RPD31 || || Putative histone deacetylase; involved in regulation of white-opaque switch; Spider biofilm repressed || 1 0.18 0.24 -0.17 -0.32 0.16 -0.17 0.35 0.34 0.03 0.17 0.74 0.61 0.02 0.59 0.34 0.91
2637 || orf19.3168 || RPN8 || || Putative regulatory subunit of the 26S proteasome; mutation confers hypersensitivity to amphotericin B; regulated by Mig1, Gcn2 and Gcn4; Spider biofilm repressed || 1 0.04 0.13 -0.44 -0.35 -0.29 -0.43 0.44 0.35 -0.12 0.03 1.01 0.72 -0.12 0.45 0.63 0.98
2638 || orf19.5260 || RPN2 || || Putative 26S proteasome subunit; transcript regulated by Mig1; caspofungin repressed; regulated by Gcn2 and Gcn4; gene used for strain identification by multilocus sequence typing || 1 0.18 0.01 -0.35 -0.31 -0.20 -0.66 0.72 0.82 0.19 0.17 0.84 0.68 0.03 0.22 0.89 0.86
2639 || orf19.5093 || || || Ortholog(s) have DNA translocase activity || 1 0.31 0.19 -0.79 0.12 -0.45 -0.35 0.93 0.98 0.47 0.63 1.36 0.66 0.20 0.50 0.57 0.37
2640 || orf19.2895 || VMA8 || || Putative vacuolar H+-ATPase subunit; regulated by Nrg1 and Mig1; transcript increases in populations of cells exposed to fluconazole over multiple generations; rat catheter and Spider biofilm repressed || 1 0.09 -0.01 -0.28 -0.24 -0.17 -0.55 0.52 0.78 0.29 0.31 1.13 0.80 0.32 0.79 0.24 0.00
2641 || orf19.2895 || VMA8 || || Putative vacuolar H+-ATPase subunit; regulated by Nrg1 and Mig1; transcript increases in populations of cells exposed to fluconazole over multiple generations; rat catheter and Spider biofilm repressed || 1 0.07 0.00 -0.46 -0.37 -0.30 -0.67 0.78 0.90 0.21 0.19 1.22 0.64 0.34 0.62 0.05 0.58
2642 || orf19.426 || || || Ortholog of C. dubliniensis CD36 : Cd36_05120, C. parapsilosis CDC317 : CPAR2_107740, Candida tenuis NRRL Y-1498 : CANTEDRAFT_136277 and Debaryomyces hansenii CBS767 : DEHA2A02266g || 1 -0.10 0.00 -0.21 -0.20 -0.23 -0.44 0.53 0.77 0.30 0.33 0.82 0.53 0.25 0.69 0.41 0.35
2643 || orf19.5093 || || || Ortholog(s) have DNA translocase activity || 1 -0.17 -0.14 -0.26 -0.35 -0.56 -0.55 0.56 0.84 0.22 0.49 1.00 0.67 0.24 0.39 0.24 0.56
2644 || orf19.1143 || || || Ortholog of Pichia stipitis Pignal : PICST_30878, Spathaspora passalidarum NRRL Y-27907 : SPAPADRAFT_60017, Candida guilliermondii ATCC 6260 : PGUG_05223 and Candida tropicalis MYA-3404 : CTRG_01052 || 1 -0.14 0.10 -0.79 -0.35 -0.50 -0.57 0.95 1.18 0.58 0.66 1.32 1.12 0.04 0.71 0.50 1.09
2645 || orf19.2983 || CDC73 || || Putative transcription elongation factor; cdc73 kap114 double transposon mutation affects filamentous growth; Spider biofilm repressed || 1 -0.10 -0.17 0.05 -0.20 -0.32 -0.54 0.60 0.87 0.49 0.34 0.96 0.87 0.25 0.58 0.28 0.93
2646 || orf19.1837 || TBP1 || || Transcription initiation factor; binds TATA box sequence, binding does not require TFIIA; caspofungin repressed; functional homolog of S. cerevisiae and human TATA-binding proteins; Spider biofilm induced || 1 -0.29 -0.18 -0.12 -0.32 -0.28 -0.17 0.48 0.65 0.31 0.28 0.47 0.63 0.14 0.47 0.29 0.46
2647 || orf19.482 || RPT4 || || 26S proteasome regulatory subunit; regulated by Gcn2p and Gcn4p; protein level decreases in stationary phase cultures || 1 -0.10 -0.01 -0.12 -0.19 0.01 -0.28 0.25 0.67 0.64 0.42 0.88 0.64 0.33 0.34 0.48 0.43
2648 || orf19.4079 || SLP2 || || Protein similar to stomatin mechanoreception protein || 1 -0.40 0.05 -0.43 -0.32 -0.27 -0.60 0.41 0.78 0.16 0.57 0.50 0.52 0.26 0.10 0.69 0.43
2649 || orf19.4079 || SLP2 || || Protein similar to stomatin mechanoreception protein || 1 -0.34 -0.22 -0.51 -0.22 -0.21 -0.46 0.60 0.60 -0.04 0.67 0.57 0.57 0.45 0.42 0.27 0.59
2650 || orf19.4079 || SLP2 || || Protein similar to stomatin mechanoreception protein || 1 -0.01 -0.43 -0.60 -0.33 -0.14 -0.74 0.59 0.71 -0.17 0.59 0.44 0.62 0.30 0.31 0.18 0.70
2651 || orf19.245 || DDC1 || || Putative DNA damage checkpoint protein; transcript induced during filamentous growth; regulated by Nrg1, Tup1 || 1 -0.02 -0.24 -0.75 -0.63 0.21 -0.19 0.49 1.02 0.13 0.81 0.28 0.61 0.08 0.72 0.43 0.72
2652 || orf19.2728 || || || Ortholog(s) have DNA clamp loader activity, role in DNA damage checkpoint, nucleotide-excision repair, reciprocal meiotic recombination and Rad17 RFC-like complex, nucleus localization || 1 0.00 0.14 -0.66 -0.35 0.26 -0.30 0.53 0.88 0.46 0.40 0.32 0.86 0.22 0.75 0.57 0.88
2653 || orf19.2728 || || || Ortholog(s) have DNA clamp loader activity, role in DNA damage checkpoint, nucleotide-excision repair, reciprocal meiotic recombination and Rad17 RFC-like complex, nucleus localization || 1 -0.11 -0.06 -0.53 -0.25 0.12 -0.46 0.28 0.69 0.24 0.46 0.42 0.75 -0.14 0.40 0.45 0.88
2654 || orf19.2642 || || || Ortholog(s) have myosin II binding activity, role in actomyosin contractile ring contraction and cellular bud neck contractile ring localization || 1 -0.23 -0.67 -0.49 -0.19 -0.06 -0.79 0.39 0.33 0.38 0.53 1.38 0.87 -0.13 0.62 0.34 0.62
2655 || orf19.2794 || || || Putative non-specific single-domain racemase; regulated by Gcn4p; repressed in response to amino acid starvation (3-AT treatment); alkaline upregulated; macrophage-induced protein || 1 -0.26 -0.62 -0.81 -0.27 -0.34 -0.46 0.31 0.46 -0.08 0.69 0.86 0.47 -0.06 0.82 0.24 0.56
2656 || orf19.7478 || || || Ortholog(s) have antioxidant activity, di-trans,poly-cis-decaprenylcistransferase activity, protein heterodimerization activity, trans-hexaprenyltranstransferase activity || 1 -0.33 -0.19 -0.39 -0.80 -0.20 -0.32 0.08 0.59 0.29 0.59 0.58 0.72 0.21 0.37 0.55 -0.05
2657 || orf19.3205 || MPRL36 || || Mitochondrial ribosomal protein of the large subunit; rat catheter biofilm induced || 1 -0.59 -0.42 -0.36 -0.95 0.54 -0.33 0.89 1.22 0.39 0.93 0.94 0.64 0.75 0.21 1.34 -0.55
2658 || orf19.1261 || CGT1 || || mRNA 5' guanylyltransferase; small subunit of mRNA capping enzyme; binds an RNA Pol II C-terminal domain peptide; Cet1p and Cgt1p form a 2:1 complex; functional homolog of S. cerevisiae Ceg1p || 1 -0.20 -0.17 -0.42 -0.46 -0.16 -0.15 0.41 0.40 0.12 0.48 0.46 0.40 0.81 0.75 0.44 0.18
2659 || orf19.1260 || LEA1 || || Predicted component of U2 snRNP; induced by alpha pheromone in SpiderM medium || 1 -0.18 -0.16 -0.60 -0.76 0.02 0.04 0.50 0.69 0.10 0.85 0.92 0.82 0.56 0.99 0.43 0.04
2660 || orf19.6891 || RFC1 || || Putative DNA replication factor C subunit; ortholog of S. cerviaie Rfc1; likely essential, based on an insertional mutagenesis strategy; rat catheter biofilm repressed || 1 -0.03 0.03 -0.39 -0.67 0.42 -0.44 0.51 0.59 0.11 0.40 0.62 0.15 0.21 0.55 0.06 0.33
2661 || orf19.4518 || || || Protein kinase of unknown function; mutants are viable || 1 0.07 -0.05 -1.02 -1.09 1.00 -0.72 0.41 0.60 0.26 0.45 0.81 0.42 0.57 0.60 0.35 0.14
2662 || orf19.5574 || || || Ortholog(s) have mitochondrial outer membrane localization || 1 0.08 -0.28 -0.71 -0.87 0.71 -0.15 0.33 0.20 0.35 0.83 0.37 0.47 0.52 0.56 0.46 0.11
2663 || orf19.7223 || || || Ortholog(s) have protein-lysine N-methyltransferase activity, role in peptidyl-lysine monomethylation and cytosol, nucleus localization || 1 0.09 -0.22 -1.35 -1.48 0.61 -0.17 0.42 0.77 0.51 1.04 0.66 0.08 0.85 0.27 0.36 0.52
2664 || orf19.3367 || || || Ortholog(s) have structural constituent of ribosome activity and mitochondrial large ribosomal subunit localization || 1 0.04 -0.51 -0.31 -0.85 0.08 -0.50 0.65 1.09 0.57 1.12 0.30 0.34 0.48 0.44 0.62 -0.07
2665 || orf19.7222 || PAM16 || || Putative maltase; regulated by Gcn4; repressed by amino acid starvation (3-AT); rat catheter biofilm induced || 1 0.00 -0.37 -0.52 -0.79 -0.15 -0.52 0.49 0.55 0.32 0.52 0.19 -0.05 0.13 0.21 0.47 -0.31
2666 || orf19.4656 || || || Ortholog of C. dubliniensis CD36 : Cd36_41300, C. parapsilosis CDC317 : CPAR2_400390, Candida tenuis NRRL Y-1498 : CANTEDRAFT_94704 and Debaryomyces hansenii CBS767 : DEHA2B02992g || 1 -0.22 -0.35 -0.49 -1.17 0.01 -0.68 0.61 0.49 0.07 0.70 0.46 0.30 0.40 0.36 0.74 0.10
2667 || orf19.1396 || || || Ortholog(s) have ARF GTPase activator activity, role in ER to Golgi vesicle-mediated transport, intra-Golgi vesicle-mediated transport and Golgi apparatus, clathrin-coated vesicle localization || 1 -0.07 -0.19 -0.31 -0.39 -0.11 -0.47 0.66 0.58 0.01 0.34 0.81 0.27 0.67 0.14 0.45 0.60
2668 || orf19.4340 || || || Ortholog of C. dubliniensis CD36 : Cd36_52890, C. parapsilosis CDC317 : CPAR2_501970, Candida tenuis NRRL Y-1498 : CANTEDRAFT_113546 and Debaryomyces hansenii CBS767 : DEHA2E09900g || 1 -0.57 -0.37 -0.83 -0.79 -0.43 -0.77 1.13 1.08 0.37 0.67 1.46 0.66 0.76 0.50 0.78 0.75
2669 || orf19.1168 || ZCF3 || || Zn(II)2Cys6 domain transcription factor; required for filamentous growth, resistance to rapamycin and flucytosine; possibly an essential gene, disruptants not obtained by UAU1 method; Hap43-repressed; Spider and flow model biofilm induced || 1 -0.93 -0.60 -1.41 -1.10 -0.60 -1.10 1.27 1.45 0.46 0.32 1.63 0.85 0.76 0.57 1.72 0.40
2670 || orf19.1168 || ZCF3 || || Zn(II)2Cys6 domain transcription factor; required for filamentous growth, resistance to rapamycin and flucytosine; possibly an essential gene, disruptants not obtained by UAU1 method; Hap43-repressed; Spider and flow model biofilm induced || 1 -0.78 -0.29 -1.88 -1.34 -0.71 -1.33 1.68 1.43 0.20 0.08 1.48 0.68 0.40 0.30 1.63 0.68
2671 || orf19.2794 || || || Putative non-specific single-domain racemase; regulated by Gcn4p; repressed in response to amino acid starvation (3-AT treatment); alkaline upregulated; macrophage-induced protein || 1 -0.20 0.05 -1.02 -0.35 0.19 -0.76 0.63 0.91 0.02 0.57 1.01 0.37 0.52 0.36 0.37 -0.17
2672 || orf19.6829 || || || Protein with a predicted mitochondrial ATPase expression domain; possibly an essential gene, disruptants not obtained by UAU1 method || 1 -0.31 -0.45 -1.35 -1.43 0.16 -0.55 0.78 0.95 0.76 0.90 0.72 0.55 0.94 0.61 0.80 -0.13
2673 || orf19.7019 || YML6 || || Putative mitochondrial ribosomal protein; induced upon adherence to polystyrene || 1 -0.35 -0.15 -1.23 -1.18 0.13 -1.02 0.79 0.97 0.62 1.07 0.61 0.58 0.93 0.62 0.69 -0.26
2674 || orf19.3317 || MED22 || || RNA polymerase II mediator complex subunit || 1 -0.25 -0.64 -1.47 -0.75 0.18 -1.51 0.97 1.12 0.34 0.63 1.81 1.07 0.80 1.16 0.72 0.32
2675 || orf19.5518 || || || Protein of unknown function; Spider biofilm induced || 1 -0.76 -0.38 -1.46 -1.20 0.24 -1.14 0.68 1.20 -0.22 0.14 1.49 0.79 0.36 0.34 0.22 0.40
2676 || orf19.3349 || || || Putative RNA polymerase II subunit B150; heterozygous null mutant exhibits resistance to parnafungin in the C. albicans fitness test || 1 -0.12 -0.14 -1.25 -1.07 0.43 -0.59 1.00 0.83 -0.04 0.12 1.27 0.32 0.55 0.38 0.47 0.46
2677 || orf19.4851 || TFA1 || || Protein with polyglutamate motifs and abundant Ser/Thr residues; described as a subunit of TFIIE, which is a basal transcription initiation factor of RNA Polymerase II; possibly an essential gene, disruptants not obtained by UAU1 method || 1 -0.29 -0.26 -1.35 -0.71 0.19 -0.44 0.92 0.83 -0.04 0.40 1.38 0.55 0.22 0.40 0.38 0.70
2678 || orf19.5516 || || || Ortholog(s) have signal sequence binding activity, role in protein targeting to ER and cytosol, nucleus, signal recognition particle, endoplasmic reticulum targeting localization || 1 -0.25 -0.00 -1.27 -1.04 -0.05 -0.69 1.02 0.86 0.03 0.42 1.02 0.82 0.71 0.92 0.39 0.78
2679 || orf19.1260 || LEA1 || || Predicted component of U2 snRNP; induced by alpha pheromone in SpiderM medium || 1 -0.22 -0.06 -0.92 -0.72 -0.12 -0.22 0.68 0.70 -0.11 0.52 0.81 0.50 0.61 0.45 0.30 0.13
2680 || orf19.1545 || || || Ortholog(s) have structural constituent of ribosome activity and mitochondrial small ribosomal subunit localization || 1 -0.73 -0.72 -1.53 -1.95 0.86 0.25 1.13 1.81 0.62 1.33 0.83 1.01 0.54 0.84 1.15 0.63
2681 || orf19.5235 || || || Putative mitochondrial ribosomal protein of the large subunit; Hap43-induced; mutants are viable; protein level decreases in stationary phase || 1 -0.60 -0.46 -1.37 -1.60 0.60 -0.26 0.68 1.02 0.39 1.22 0.94 0.95 0.22 0.71 0.96 0.17
2682 || orf19.3700 || TOM70 || || Ortholog(s) have mitochondrion targeting sequence binding, protein channel activity and role in protein import into mitochondrial inner membrane, protein import into mitochondrial matrix || 1 -0.16 -0.27 -0.88 -0.72 0.28 0.03 0.52 0.82 0.60 1.06 0.79 0.78 -0.05 0.38 0.68 0.20
2683 || orf19.5648 || || || Ortholog of C. dubliniensis CD36 : Cd36_40300, C. parapsilosis CDC317 : CPAR2_402190, Candida tenuis NRRL Y-1498 : cten_CGOB_00197 and Debaryomyces hansenii CBS767 : DEHA2F06160g || 1 -0.45 -0.12 -0.93 -0.54 0.42 -0.30 1.26 1.10 0.08 0.66 1.35 0.50 0.18 0.14 0.46 0.52
2684 || orf19.5648 || || || Ortholog of C. dubliniensis CD36 : Cd36_40300, C. parapsilosis CDC317 : CPAR2_402190, Candida tenuis NRRL Y-1498 : cten_CGOB_00197 and Debaryomyces hansenii CBS767 : DEHA2F06160g || 1 -0.18 0.09 -1.02 -0.58 0.65 -0.22 1.49 1.32 0.20 0.80 1.71 0.74 0.22 0.22 0.64 0.11
2685 || orf19.1650 || TOM6 || || Predicted component of the TOM (translocase of outer membrane) complex, involved in protein import into mitochondria || 1 -0.11 -0.20 -1.18 -0.89 0.00 -0.96 1.55 1.88 0.51 0.38 1.78 0.45 0.42 0.32 0.32 -0.03
2686 || orf19.1650 || TOM6 || || Predicted component of the TOM (translocase of outer membrane) complex, involved in protein import into mitochondria || 1 0.14 0.03 -0.95 -1.15 0.34 -0.80 1.58 1.98 0.80 0.63 1.91 0.54 0.34 0.39 0.51 0.23
2687 || orf19.5684 || || || Ortholog(s) have structural constituent of ribosome activity and mitochondrial large ribosomal subunit localization || 1 -0.12 -0.34 -0.92 -1.16 0.01 -0.47 1.27 1.63 0.95 0.90 1.50 0.49 -0.05 0.32 0.26 0.28
2688 || orf19.6183 || TIM8 || || Predicted mitochondrial intermembrane space protein with role in protein import into mitochondrial inner membrane and cytosol || 1 -0.14 -0.17 -0.65 -0.69 0.12 -0.53 0.98 1.28 0.56 0.51 1.44 0.66 0.04 -0.00 0.60 0.53
2689 || orf19.6231 || MRPL19 || || Putative ribosomal protein; induced upon adherence to polystyrene; Spider biofilm repressed || 1 -0.27 -0.32 -1.14 -1.33 0.38 -0.40 0.85 1.11 0.52 0.78 0.93 0.87 0.05 -0.08 0.72 0.22
2690 || orf19.5747 || || || Ortholog(s) have structural constituent of ribosome activity and mitochondrial small ribosomal subunit localization || 1 -0.18 -0.03 -0.56 -0.89 -0.15 -0.31 0.52 0.93 0.43 0.85 0.66 0.41 0.38 -0.03 0.77 0.01
2691 || orf19.7012 || || || Ortholog(s) have structural constituent of ribosome activity and mitochondrial small ribosomal subunit localization || 1 -0.53 -0.61 -1.36 -1.31 -0.75 -1.17 1.39 1.74 0.50 1.10 1.31 0.51 0.40 0.20 0.90 -0.29
2692 || orf19.3704.1 || || || Ortholog(s) have structural constituent of ribosome activity and mitochondrial small ribosomal subunit localization || 1 -0.43 -0.40 -0.97 -1.11 -0.24 -0.74 1.24 1.71 0.63 1.00 1.50 0.46 0.82 0.50 0.81 0.02
2693 || orf19.6752 || || || Ortholog(s) have structural constituent of ribosome activity and mitochondrial small ribosomal subunit localization || 1 -0.20 -0.18 -1.03 -1.19 0.04 -0.96 0.93 1.36 0.17 0.92 0.98 0.52 0.58 0.59 0.89 -0.15
2694 || orf19.7012 || || || Ortholog(s) have structural constituent of ribosome activity and mitochondrial small ribosomal subunit localization || 1 -0.54 -0.39 -1.36 -1.35 -0.28 -1.06 1.27 1.70 0.69 1.29 1.51 0.79 0.75 0.53 0.98 -0.44
2695 || orf19.4176 || || || Ortholog(s) have structural constituent of ribosome activity and mitochondrial small ribosomal subunit localization || 1 -0.64 -0.09 -1.24 -1.27 -0.21 -1.24 1.10 1.61 0.60 1.47 1.08 0.75 0.80 0.37 0.73 -0.19
2696 || orf19.585 || || || Ortholog(s) have structural constituent of ribosome activity and mitochondrial large ribosomal subunit localization || 1 -0.44 -0.48 -0.81 -0.86 -0.15 -0.84 1.12 1.47 0.80 1.26 0.94 0.79 0.87 0.24 0.84 0.29
2697 || orf19.755 || MRPL37 || || Putative mitochondrial large subunit ribosomal protein; shows colony morphology-related gene regulation by Ssn6p || 1 -0.63 -0.38 -1.60 -1.54 -0.18 -0.30 1.55 1.55 0.79 1.37 1.50 0.54 0.95 0.39 0.98 0.31
2698 || orf19.7675 || || || Mitochondrial ribosomal protein of the large subunit; Spider biofilm repressed || 1 -0.64 -0.42 -1.15 -0.99 -0.06 -0.21 0.97 1.25 0.40 1.23 1.10 0.56 0.65 0.37 0.61 0.20
2699 || orf19.7675 || || || Mitochondrial ribosomal protein of the large subunit; Spider biofilm repressed || 1 -0.64 -0.52 -1.27 -1.03 -0.22 -0.28 0.76 1.30 0.41 1.11 1.09 0.43 0.56 0.03 0.55 0.20
2700 || orf19.3938 || || || Putative mitochondrial ribosomal protein of the small subunit; mutation confers hypersensitivity to 5-fluorocytosine (5-FC), 5-fluorouracil (5-FU), and tubercidin (7-deazaadenosine) || 1 -0.28 -0.36 -1.74 -1.01 -0.17 -1.02 1.33 1.25 0.38 1.10 1.41 0.83 1.23 0.56 1.20 0.50
2701 || orf19.4079 || SLP2 || || Protein similar to stomatin mechanoreception protein || 1 -0.03 -0.34 -0.64 -0.26 -0.19 -0.53 0.48 0.72 0.10 0.63 0.63 0.48 0.54 0.16 0.48 0.06
2702 || orf19.6752 || || || Ortholog(s) have structural constituent of ribosome activity and mitochondrial small ribosomal subunit localization || 1 -0.46 0.08 -1.07 -0.97 0.20 -0.63 0.75 1.50 0.29 1.10 0.98 0.76 0.74 0.77 1.00 0.02
2703 || orf19.3357 || || || Ortholog(s) have mitochondrion localization || 1 -0.54 -0.26 -1.06 -1.20 0.26 -0.32 0.43 1.14 0.32 0.68 1.17 1.01 0.52 0.11 1.14 0.13
2704 || orf19.1697 || || || Ortholog(s) have role in cytoplasmic translation and cytoplasm, polysomal ribosome localization || 1 -0.43 -0.52 -2.09 -1.75 0.22 -0.18 0.99 1.40 0.37 1.64 2.13 1.54 1.18 0.55 1.42 0.28
2705 || orf19.2520 || || || Ortholog(s) have structural constituent of ribosome activity and mitochondrial small ribosomal subunit localization || 1 -0.38 -0.23 -0.85 -0.84 0.53 -0.05 0.42 1.09 0.23 1.10 1.45 1.10 0.79 0.40 1.36 0.37
2706 || orf19.4751 || || || Ortholog(s) have structural constituent of ribosome activity and mitochondrial small ribosomal subunit localization || 1 0.10 0.06 -1.14 -1.12 -0.05 -0.35 1.11 1.22 0.06 1.22 1.18 0.85 1.02 0.40 1.30 0.15
2707 || orf19.5279 || || || Ortholog(s) have structural constituent of ribosome activity, role in aerobic respiration and mitochondrial large ribosomal subunit localization || 1 0.27 0.47 -1.11 -1.66 0.76 -0.38 1.68 1.76 0.58 1.25 1.82 0.69 1.18 0.72 1.53 0.07
2708 || orf19.5279 || || || Ortholog(s) have structural constituent of ribosome activity, role in aerobic respiration and mitochondrial large ribosomal subunit localization || 1 -0.03 0.48 -1.10 -1.04 0.41 -0.41 1.37 1.60 0.50 1.23 1.64 0.73 1.32 0.31 1.37 0.28
2709 || orf19.3938 || || || Putative mitochondrial ribosomal protein of the small subunit; mutation confers hypersensitivity to 5-fluorocytosine (5-FC), 5-fluorouracil (5-FU), and tubercidin (7-deazaadenosine) || 1 0.06 0.30 -0.77 -0.92 0.44 -0.60 1.12 1.60 0.52 1.00 1.57 0.82 1.11 0.49 1.46 0.19
2710 || orf19.2520 || || || Ortholog(s) have structural constituent of ribosome activity and mitochondrial small ribosomal subunit localization || 1 -0.03 0.09 -0.67 -1.29 0.88 -0.33 1.65 1.87 0.66 1.16 1.78 0.97 1.35 0.67 1.68 0.30
2711 || orf19.1967 || || || Ortholog(s) have structural constituent of ribosome activity and mitochondrial large ribosomal subunit localization || 1 0.11 -0.05 -0.93 -1.19 0.17 -0.57 1.41 1.87 0.64 1.16 2.12 1.22 1.19 0.34 1.36 0.09
2712 || orf19.4593.1 || || || Protein with a predicted role in mitochondrial respiratory chain complex II assembly; rat catheter biofilm induced || 1 0.11 0.15 -1.15 -0.88 0.05 -0.72 1.51 1.79 0.50 0.83 1.79 0.60 1.01 0.52 1.27 0.02
2713 || orf19.3064 || MRPL27 || || Putative 60S ribosomal protein L27, mitochondrial precursor || 1 -0.52 -0.47 -1.12 -1.35 0.46 -0.22 0.99 1.52 0.49 0.73 1.60 0.56 0.66 0.50 0.85 -0.42
2714 || orf19.2259 || || || Ortholog(s) have structural constituent of ribosome activity and mitochondrial large ribosomal subunit localization || 1 -0.38 -0.29 -1.30 -1.48 0.23 -0.34 0.99 1.25 0.47 0.93 1.95 0.58 0.91 0.12 0.82 0.28
2715 || orf19.5433 || || || Ortholog(s) have protein binding involved in protein folding activity, role in mitochondrial respiratory chain complex III assembly and mitochondrial matrix localization || 1 -0.47 -0.13 -1.25 -1.45 0.92 0.10 1.90 1.98 1.22 1.40 2.37 1.05 1.23 0.94 1.65 0.45
2716 || orf19.5433 || || || Ortholog(s) have protein binding involved in protein folding activity, role in mitochondrial respiratory chain complex III assembly and mitochondrial matrix localization || 1 -0.60 -0.56 -1.50 -1.23 0.68 -0.56 1.56 1.61 0.83 1.20 2.26 1.05 1.14 1.02 1.87 0.60
2717 || orf19.2520 || || || Ortholog(s) have structural constituent of ribosome activity and mitochondrial small ribosomal subunit localization || 1 -0.43 -0.23 -1.54 -1.43 0.74 -0.20 1.38 1.73 0.63 1.47 1.97 1.43 1.15 0.77 1.92 0.39
2718 || orf19.7203 || MRP7 || || Mitochondrial ribosomal protein of the large subunit; rat catheter biofilm induced || 1 -0.20 -0.19 -1.61 -1.81 0.67 -0.69 1.62 1.70 0.82 1.76 1.85 0.87 1.18 0.87 1.68 0.24
2719 || orf19.6129 || MRPL8 || || Mitochondrial 60S ribosomal protein subunit; Hap43p-repressed gene || 1 -0.43 0.05 -1.27 -1.46 0.51 -0.49 1.63 1.58 0.89 1.39 1.72 1.01 1.05 0.61 1.17 0.38
2720 || orf19.3357 || || || Ortholog(s) have mitochondrion localization || 1 -0.52 -0.50 -1.03 -1.42 0.38 -0.36 1.15 1.32 0.42 1.19 1.21 0.78 1.11 0.59 1.17 0.13
2721 || orf19.2520 || || || Ortholog(s) have structural constituent of ribosome activity and mitochondrial small ribosomal subunit localization || 1 -0.70 -0.52 -2.07 -1.30 0.69 -0.14 1.48 1.50 0.61 1.35 1.75 1.09 1.18 0.37 1.75 0.28
2722 || orf19.4018 || || || Ortholog(s) have structural constituent of ribosome activity and mitochondrial small ribosomal subunit localization || 1 -0.66 -0.34 -1.26 -1.32 0.29 -0.45 1.04 1.67 0.71 1.10 1.22 0.83 0.56 0.35 0.85 0.03
2723 || orf19.439 || || || Ortholog(s) have recombinase activity, single-stranded DNA binding activity || 1 -0.36 -0.53 -1.26 -1.25 0.25 -0.31 1.35 1.41 0.91 0.92 1.18 1.13 0.61 0.44 0.88 0.25
2724 || orf19.3348 || || || Ortholog(s) have structural constituent of ribosome activity and mitochondrial large ribosomal subunit localization || 1 -0.77 -0.58 -1.39 -1.34 0.37 -0.19 1.37 1.30 0.88 1.37 1.70 0.99 0.64 0.56 0.99 0.13
2725 || orf19.3348 || || || Ortholog(s) have structural constituent of ribosome activity and mitochondrial large ribosomal subunit localization || 1 -0.84 -0.68 -2.09 -1.79 0.49 -0.24 1.58 1.64 0.80 1.01 2.06 1.34 0.69 0.59 1.36 0.71
2726 || orf19.3064 || MRPL27 || || Putative 60S ribosomal protein L27, mitochondrial precursor || 1 -0.77 -0.57 -2.00 -1.92 0.61 -0.09 1.41 1.94 0.67 1.01 1.91 0.97 0.86 0.46 1.32 0.35
2727 || orf19.3064 || MRPL27 || || Putative 60S ribosomal protein L27, mitochondrial precursor || 1 -0.67 -0.43 -1.51 -1.39 0.81 -0.02 1.41 1.93 0.61 1.13 1.95 0.93 0.80 0.60 1.28 0.41
2728 || orf19.3064 || MRPL27 || || Putative 60S ribosomal protein L27, mitochondrial precursor || 1 -0.38 -0.40 -1.91 -1.78 0.71 -0.18 1.20 1.72 0.21 0.81 1.71 0.68 0.64 0.19 1.14 0.26
2729 || orf19.397 || || || Ortholog(s) have structural constituent of ribosome activity and cytosol, mitochondrial large ribosomal subunit, nucleus localization || 1 -0.37 -0.25 -2.08 -1.92 0.84 -0.09 1.56 2.00 0.68 0.67 1.62 0.70 0.69 0.28 1.09 0.27
2730 || orf19.549 || || || Ortholog(s) have structural constituent of ribosome activity and mitochondrial inner membrane, mitochondrial large ribosomal subunit localization || 1 0.10 0.16 -1.64 -1.47 0.39 -0.44 1.37 1.67 0.39 0.79 1.49 0.44 0.78 0.48 1.01 0.06
2731 || orf19.1485 || || || Mitochondrial ribosomal protein of the large subunit; rat catheter biofilm induced || 1 -0.28 -0.17 -1.75 -1.77 0.47 -0.73 1.84 2.18 0.48 0.77 2.06 0.53 1.01 0.65 1.27 0.53
2732 || orf19.6406 || || || Ortholog(s) have role in regulation of sporulation resulting in formation of a cellular spore and cytosol, mitochondrial ribosome, nucleus localization || 1 -0.08 -0.08 -0.82 -1.23 0.36 -0.53 0.99 1.33 0.26 0.56 1.30 0.57 0.60 0.32 0.69 0.18
2733 || orf19.3704.1 || || || Ortholog(s) have structural constituent of ribosome activity and mitochondrial small ribosomal subunit localization || 1 -0.46 -0.17 -1.39 -1.41 -0.15 -0.60 1.56 1.93 0.67 0.87 1.43 0.68 0.75 0.65 1.00 0.56
2734 || orf19.6461 || || || Ortholog(s) have unfolded protein binding activity, role in aerobic respiration, mitochondrial respiratory chain complex IV assembly, protein processing and mitochondrial inner membrane localization || 1 -0.15 -0.27 -0.80 -0.88 0.46 -0.39 1.03 1.17 0.41 0.61 0.74 0.27 0.50 0.31 0.82 0.25
2735 || orf19.51 || || || Ortholog(s) have role in mitochondrion organization, translational initiation and eukaryotic translation initiation factor 3 complex localization || 1 -0.01 -0.04 -0.98 -1.04 0.05 -0.32 0.96 0.79 0.49 0.68 0.77 0.42 0.52 0.38 0.83 0.23
2736 || orf19.5161 || || || Ortholog(s) have structural constituent of ribosome activity and mitochondrial large ribosomal subunit localization || 1 -0.02 0.01 -0.99 -0.93 -0.02 -0.34 0.99 1.46 0.36 0.75 1.34 0.75 0.17 0.25 1.01 0.25
2737 || orf19.5433 || || || Ortholog(s) have protein binding involved in protein folding activity, role in mitochondrial respiratory chain complex III assembly and mitochondrial matrix localization || 1 -0.32 -0.04 -1.38 -1.46 0.03 0.18 1.63 2.21 0.74 1.05 1.83 1.40 0.78 0.60 1.86 0.82
2738 || orf19.4023 || MRP2 || || Protein similar to S. cerevisiae Mrp2p, which is a component of the small subunit of the mitochondrial ribosome; transposon mutation affects filamentous growth || 1 -0.12 -0.13 -1.01 -0.99 0.65 0.10 1.05 1.57 0.89 0.92 1.31 0.69 0.39 -0.02 1.00 0.25
2739 || orf19.4023 || MRP2 || || Protein similar to S. cerevisiae Mrp2p, which is a component of the small subunit of the mitochondrial ribosome; transposon mutation affects filamentous growth || 1 -0.11 -0.05 -1.18 -1.15 0.81 0.04 0.98 1.54 0.66 0.76 1.28 0.52 0.34 0.24 0.98 0.25
2740 || orf19.1485 || || || Mitochondrial ribosomal protein of the large subunit; rat catheter biofilm induced || 1 -0.14 0.10 -2.31 -0.88 0.96 -0.80 2.15 2.10 0.49 0.73 2.05 0.80 1.12 0.49 1.61 0.08
2741 || orf19.6696 || TIM9 || || Predicted protein of the mitochondrial intermembrane space; rat catheter biofilm induced; Spider biofilm repressed || 1 -0.20 -0.17 -1.57 -1.14 0.75 -0.76 1.53 2.02 0.53 1.32 2.05 0.71 0.22 0.47 1.25 -0.28
2742 || orf19.6696 || TIM9 || || Predicted protein of the mitochondrial intermembrane space; rat catheter biofilm induced; Spider biofilm repressed || 1 -0.44 -0.43 -2.35 -1.62 0.38 -1.08 1.34 2.03 0.29 0.80 1.82 0.51 -0.17 0.44 1.20 -0.23
2743 || orf19.4577.3 || TIM10 || || Predicted protein of the mitochondrial intermembrane space with role in protein import into mitochondrial inner membrane || 1 -0.61 -0.52 -2.08 -1.42 0.69 -0.80 1.69 2.02 0.32 0.51 1.99 0.46 0.35 0.07 0.82 -0.09
2744 || orf19.4577.3 || TIM10 || || Predicted protein of the mitochondrial intermembrane space with role in protein import into mitochondrial inner membrane || 1 -0.23 -0.46 -1.41 -1.06 0.47 -0.71 1.55 1.75 0.39 0.44 2.08 0.05 0.26 -0.17 0.79 -0.55
2745 || orf19.1109 || || || Ortholog of C. dubliniensis CD36 : Cd36_53580, C. parapsilosis CDC317 : CPAR2_303030, Debaryomyces hansenii CBS767 : DEHA2G07766g and Pichia stipitis Pignal : psti_CGOB_00176 || 1 0.24 0.27 -1.41 -1.16 0.44 -0.53 1.71 1.65 0.06 0.35 1.64 0.27 0.87 0.13 0.96 -0.22
2746 || orf19.639.1 || || || Ortholog(s) have structural constituent of ribosome activity and mitochondrial large ribosomal subunit localization || 1 0.18 0.13 -1.21 -1.13 -0.17 -0.62 1.27 1.63 0.14 0.69 1.22 0.35 0.56 0.03 0.71 0.00
2747 || orf19.7613 || HCR1 || || Putative translation initiation factor; repressed upon phagocytosis by murine macrophage; Spider biofilm repressed || 1 0.10 -0.08 -0.98 -1.12 0.28 -0.43 0.84 0.98 0.11 0.51 1.00 0.17 0.30 0.14 0.22 -0.03
2748 || orf19.5235 || || || Putative mitochondrial ribosomal protein of the large subunit; Hap43-induced; mutants are viable; protein level decreases in stationary phase || 1 -0.58 0.01 -1.35 -1.51 0.79 -0.38 0.94 1.08 0.62 1.28 1.17 0.91 1.28 0.14 1.13 0.01
2749 || orf19.7203 || MRP7 || || Mitochondrial ribosomal protein of the large subunit; rat catheter biofilm induced || 1 -0.33 0.40 -0.54 -0.65 0.01 -0.31 1.18 1.43 0.87 1.64 1.26 1.04 0.58 0.54 0.97 0.36
2750 || orf19.439 || || || Ortholog(s) have recombinase activity, single-stranded DNA binding activity || 1 -0.41 -0.14 -0.88 -0.87 -0.01 -0.32 1.24 1.17 0.99 1.43 1.41 0.92 0.36 0.56 0.94 0.13
2751 || orf19.4176 || || || Ortholog(s) have structural constituent of ribosome activity and mitochondrial small ribosomal subunit localization || 1 -0.31 -0.42 -1.01 -0.88 -0.27 -0.44 0.92 1.41 0.96 1.34 1.16 1.27 0.77 0.96 0.74 0.26
2752 || orf19.5269 || || || Ortholog of C. dubliniensis CD36 : Cd36_11210, C. parapsilosis CDC317 : CPAR2_805180, Candida tenuis NRRL Y-1498 : CANTEDRAFT_116279 and Debaryomyces hansenii CBS767 : DEHA2B10714g || 1 -0.20 -0.38 -0.67 -0.33 -0.13 -0.37 0.80 0.94 0.60 0.65 0.89 0.56 0.61 0.60 0.69 0.52
2753 || orf19.7223 || || || Ortholog(s) have protein-lysine N-methyltransferase activity, role in peptidyl-lysine monomethylation and cytosol, nucleus localization || 1 0.42 -0.37 -0.82 -1.68 -0.03 -0.48 1.44 1.49 0.71 1.17 1.45 0.66 0.55 0.13 0.59 0.30
2754 || orf19.6033 || CMP1 || || Catalytic subunit of calcineurin (Ca[2+]-calmodulin-regulated S/T protein phosphatase); required for wild-type virulence, resistance to high pH, Na(+), Li(+), Mn(2+), and fluconazole tolerance; micafungin is fungicidal to null mutant || 1 -0.01 0.10 -0.89 -0.52 0.01 -0.42 1.06 0.91 0.55 0.81 0.93 0.10 0.71 0.04 0.60 -0.06
2755 || orf19.4418 || FMT1 || || Putative methionyl-tRNA transformylase; induced upon adherence to polystyrene || 1 0.18 0.17 -1.05 -0.52 0.08 -0.27 1.27 0.89 0.80 0.75 0.82 0.54 1.03 0.50 0.59 -0.05
2756 || orf19.7613 || HCR1 || || Putative translation initiation factor; repressed upon phagocytosis by murine macrophage; Spider biofilm repressed || 1 0.06 -0.01 -1.06 -1.05 0.45 -0.39 1.04 1.19 0.26 0.81 0.95 0.26 0.47 1.00 0.37 -0.10
2757 || orf19.4297 || CKB2 || || Regulatory subunit of protein kinase CK2 (casein kinase II), beta' subunit; null mutants are hypersensitive to caspofungin || 1 0.15 0.07 -0.38 -0.43 0.04 -0.16 0.49 0.58 -0.03 0.31 0.56 0.26 0.20 0.38 0.13 -0.03
2758 || orf19.5160 || || || Ortholog(s) have role in G1/S transition of mitotic cell cycle, TOR signaling cascade, dephosphorylation, regulation of mitotic sister chromatid segregation, tRNA wobble uridine modification || 1 0.32 0.43 -1.15 -1.17 0.09 -0.56 0.68 0.99 0.19 0.73 1.17 0.70 0.53 0.88 0.45 0.34
2759 || orf19.2920 || || || Ortholog(s) have role in ribosome biogenesis and cytosol, ribosome localization || 1 -0.25 -0.15 -0.98 -0.65 0.05 -0.21 0.35 0.88 -0.21 0.63 1.12 0.45 0.06 0.36 0.38 -0.01
2760 || orf19.5351 || TIF11 || || Translation initiation factor eIF1a; possibly transcriptionally regulated upon hyphal formation; genes encoding ribosomal subunits, translation factors, and tRNA synthetases are downregulated upon phagocytosis by murine macrophage || 1 -0.16 -0.18 -1.34 -1.10 -0.10 -0.87 1.11 1.90 0.21 1.16 2.21 0.92 0.18 0.37 0.59 0.70
2761 || orf19.5351 || TIF11 || || Translation initiation factor eIF1a; possibly transcriptionally regulated upon hyphal formation; genes encoding ribosomal subunits, translation factors, and tRNA synthetases are downregulated upon phagocytosis by murine macrophage || 1 -0.22 0.05 -0.82 -0.59 -0.05 -0.49 0.75 1.69 0.23 1.29 1.81 1.16 0.28 0.46 0.20 0.44
2762 || orf19.2920 || || || Ortholog(s) have role in ribosome biogenesis and cytosol, ribosome localization || 1 -0.02 -0.01 -0.28 -0.33 -0.10 -0.02 0.32 0.82 -0.09 0.42 0.89 0.58 0.05 0.28 0.30 0.07
2763 || orf19.6692 || MNN26 || || Putative alpha-1,2-mannosyltransferase; mutant sensitive to calcofluor, SDS and growth at 42 deg; present in detergent-resistant membrane fraction (possible lipid raft component); predicted N-terminal acetylation and transmembrane helix || 1 -0.12 0.20 -0.80 -0.39 0.39 -0.13 0.62 0.58 0.24 0.79 0.54 0.54 0.17 0.11 0.60 -0.09
2764 || orf19.639.1 || || || Ortholog(s) have structural constituent of ribosome activity and mitochondrial large ribosomal subunit localization || 1 -0.31 0.08 -0.46 -0.57 0.00 -0.26 0.51 1.18 0.69 0.87 0.79 0.65 0.06 0.19 0.27 0.04
2765 || orf19.6008.4 || || || Ortholog(s) have mitochondrion localization || 1 0.24 0.17 -0.55 -0.73 0.06 -0.47 0.73 1.24 0.78 1.02 0.55 0.51 0.27 0.44 0.41 0.08
2766 || orf19.2984 || MST1 || || Ortholog(s) have role in mitochondrial threonyl-tRNA aminoacylation and mitochondrion localization || 1 -0.06 -0.22 -0.38 -0.81 0.38 -0.53 0.60 0.67 0.81 0.71 0.62 0.39 0.05 0.07 0.49 0.15
2767 || orf19.2532 || PRS || || Putative prolyl-tRNA synthetase; monofunctional Class II synthetase; gene is constitutively expressed || 1 -0.29 -0.76 -1.34 -1.00 0.54 -0.13 1.07 0.78 1.19 0.87 1.00 0.85 0.85 0.19 1.22 0.17
2768 || orf19.5297 || || || Ortholog(s) have phosphatidylinositol-3-phosphate binding, phosphatidylinositol-5-phosphate binding activity || 1 -0.67 -0.75 -0.84 -1.01 0.01 0.02 0.70 0.34 0.84 0.30 0.63 0.69 0.74 0.72 0.64 0.90
2769 || orf19.3698 || || || Protein of unknown function that may function in RNA processing; filament induced || 1 -0.51 -0.97 -1.25 -1.27 -0.23 -0.26 0.59 0.61 0.51 0.32 0.96 1.01 0.65 0.80 0.58 0.45
2770 || orf19.1143 || || || Ortholog of Pichia stipitis Pignal : PICST_30878, Spathaspora passalidarum NRRL Y-27907 : SPAPADRAFT_60017, Candida guilliermondii ATCC 6260 : PGUG_05223 and Candida tropicalis MYA-3404 : CTRG_01052 || 1 -0.20 -0.47 -0.88 -0.88 0.02 -0.38 0.23 0.64 0.44 0.79 0.97 0.76 0.27 0.85 0.36 0.63
2771 || orf19.481 || GCD1 || || Putative translation initiation factor; transcript regulated by Mig1; repressed upon phagocytosis by murine macrophage || 1 -0.29 -0.28 -0.86 -0.78 0.17 -0.34 0.42 0.65 0.41 0.66 0.74 0.65 0.35 0.88 0.51 1.03
2772 || orf19.3796 || DCR1 || || Putative Dicer RNAse involved in RNA interference, similar to S. cerevisiae Rnt1p but orthologous to S. castellii Dcr1p, which is not conserved in S. cerevisiae || 1 -0.77 -0.40 -1.23 -1.31 0.04 -0.14 0.66 0.72 0.30 0.46 1.22 0.54 0.14 0.55 0.22 1.42
2773 || orf19.2606 || HDA1 || || Histone deacetylase; inducer of filamentation; conserved deacetylation motif; regulates white-to-opaque switch frequency but not opaque-to-white switch; greater expression in white cells than opaque cells; inhibited by trichostatin-A; || 1 -0.71 -0.47 -1.05 -1.16 -0.14 -0.35 0.74 0.57 0.48 0.42 0.76 0.69 0.03 0.71 0.28 0.76
2774 || orf19.481 || GCD1 || || Putative translation initiation factor; transcript regulated by Mig1; repressed upon phagocytosis by murine macrophage || 1 -0.73 -0.72 -1.00 -0.97 -0.14 -0.39 0.90 1.01 0.63 0.80 1.02 0.55 0.32 0.51 0.35 0.62
2775 || orf19.2128 || || || Ortholog(s) have mitochondrion localization || 1 -0.87 -0.75 -0.92 -1.09 0.05 -0.56 0.61 0.71 0.62 0.66 0.93 0.41 -0.01 0.19 0.24 0.64
2776 || orf19.1624 || || || Non-catalytic subunit of N-terminal acetyltransferase of the NatC type; flow model biofilm repressed || 1 -0.37 -0.54 -1.07 -0.88 -0.65 -0.69 0.75 0.92 0.43 0.70 0.96 0.75 0.05 0.55 -0.05 0.93
2777 || orf19.407 || GCD6 || || Ortholog of S. cerevisiae Gcd6; catalytic epsilon subunit of the translation initiation factor eIF2B; genes encoding translation factors are repressed by phagocytosis by murine macrophages || 1 -0.30 -0.31 -0.64 -0.61 -0.00 -0.21 -0.09 0.28 0.01 0.46 0.44 0.39 0.03 0.50 0.16 0.33
2778 || orf19.1096 || || || Has domain(s) with predicted voltage-gated chloride channel activity, role in chloride transport, transmembrane transport and membrane localization || 1 -0.08 -0.13 -0.75 -0.50 -0.10 -0.07 0.26 0.41 0.30 0.12 0.43 0.60 0.21 0.41 0.02 0.17
2779 || orf19.6268 || || || Putative cohesin complex subunit; expression downregulated in an ssr1 null mutant || 1 -0.04 -0.13 -0.58 -0.57 -0.14 -0.50 0.79 0.65 0.56 0.50 0.37 0.73 0.33 0.51 0.61 0.43
2780 || orf19.6344 || RBK1 || || Ortholog(s) have cytosol, nucleus localization || 1 -0.16 -0.30 -0.66 -0.40 -0.25 -0.62 0.75 0.70 0.58 0.64 0.44 0.44 0.20 0.54 0.11 0.28
2781 || orf19.3559 || || || S. cerevisiae ortholog Mrps35p is a structural constituent of ribosome and localizes to mitochondrial small ribosomal subunit; the snoRNA CD39 is encoded within the MRPS35 intron || 1 0.01 -0.03 -0.74 -0.83 0.03 -0.56 0.34 0.82 0.51 0.85 0.40 0.86 0.44 -0.36 0.40 0.13
2782 || orf19.1828 || BUD16 || || Putative pyridoxal kinase; a key enzyme in pyridoxal 5'-phosphate synthesis, the active form of vitamin B6; involved in bud-site selection and genome integrity in S. cerevisiae; induced by alpha pheromone in SpiderM medium || 1 0.09 -0.25 -0.84 -0.86 0.05 -0.61 0.55 0.96 0.38 0.69 0.60 1.15 1.07 0.22 0.86 0.48
2783 || orf19.2639 || || || Ortholog(s) have structural constituent of ribosome activity and mitochondrial large ribosomal subunit localization || 1 -0.33 0.05 -0.50 -1.12 0.24 -0.89 0.59 0.41 0.37 1.06 0.42 0.98 1.05 0.22 0.67 0.10
2784 || orf19.1697 || || || Ortholog(s) have role in cytoplasmic translation and cytoplasm, polysomal ribosome localization || 1 0.08 -0.08 -1.93 -1.28 -0.56 -0.25 0.90 1.00 0.02 1.62 1.49 1.33 1.11 0.29 1.15 0.27
2785 || orf19.5009 || || || Ortholog(s) have cytoplasm localization || 1 -0.16 -0.15 -0.59 -0.38 -0.41 -0.01 0.33 0.44 0.02 0.84 0.34 0.45 0.41 -0.04 0.36 0.07
2786 || orf19.3214 || || || Alpha/beta-HydrolasE superfamily protein; membrane-localized || 1 -0.17 -0.36 -0.96 -0.81 -0.15 -0.86 0.60 1.04 0.15 0.78 0.19 0.40 1.04 0.76 0.73 0.50
2787 || orf19.1718 || ZCF8 || || Predicted Zn(II)2Cys6 transcription factor; repressed by fluphenazine treatment; required for yeast cell adherence to silicone substrate || 1 -0.06 0.17 -0.55 -0.47 0.29 -0.33 0.42 0.59 0.32 0.26 0.73 0.22 0.60 1.20 0.60 0.44
2788 || orf19.5343 || ASH1 || || GATA-like transcription factor; localizes to daughter cell, hyphal tip cell nuclei; mRNA localization mediated by She3; required for WT virulence and filamentous growth on solid media; Ras1 repressed in yeast, Cyr1 repressed yeast, hyphae || 1 0.03 -0.12 -0.38 -0.11 -0.61 -0.51 0.86 0.92 0.27 0.36 0.84 0.66 1.24 0.88 0.75 0.38
2789 || orf19.8 || || || Ortholog of C. dubliniensis CD36 : Cd36_32690, C. parapsilosis CDC317 : CPAR2_204290, Candida tenuis NRRL Y-1498 : CANTEDRAFT_121459 and Debaryomyces hansenii CBS767 : DEHA2E03938g || 1 -0.19 -0.28 -0.58 -0.61 -0.36 -0.04 1.00 0.96 0.71 0.03 0.62 0.55 1.25 1.37 0.58 0.57
2790 || orf19.8 || || || Ortholog of C. dubliniensis CD36 : Cd36_32690, C. parapsilosis CDC317 : CPAR2_204290, Candida tenuis NRRL Y-1498 : CANTEDRAFT_121459 and Debaryomyces hansenii CBS767 : DEHA2E03938g || 1 -0.56 -0.39 0.06 -0.18 0.07 -0.16 1.09 0.74 0.54 0.07 0.99 0.14 1.11 1.18 0.49 0.67
2791 || orf19.7360 || || || Ortholog(s) have enzyme activator activity, role in histone deubiquitination, regulation of transcription from RNA polymerase II promoter and DUBm complex, SAGA complex localization || 1 -0.05 -0.19 -0.10 -0.29 0.18 0.19 0.89 0.69 0.41 0.02 0.47 0.06 0.72 1.02 0.85 0.14
2792 || orf19.1011 || MNN21 || || Ortholog(s) have alpha-1,2-mannosyltransferase activity, role in cell wall mannoprotein biosynthetic process and Golgi apparatus localization || 1 -0.12 -0.00 -0.42 -0.31 -0.03 -0.24 1.29 0.97 0.84 0.15 0.27 0.06 1.06 0.76 0.12 0.39
2793 || orf19.6978 || || || Planktonic growth-induced gene || 1 0.43 0.36 0.14 -0.28 0.05 -0.30 0.84 0.93 0.53 -0.05 0.29 0.54 1.43 0.83 0.05 0.46
2794 || orf19.4079 || SLP2 || || Protein similar to stomatin mechanoreception protein || 1 0.05 -0.00 -0.13 0.05 0.16 -0.23 0.64 1.21 0.24 0.33 0.53 0.68 1.42 0.16 0.44 0.51
2795 || orf19.5491 || || || Ortholog of C. dubliniensis CD36 : Cd36_20670, C. parapsilosis CDC317 : CPAR2_104720, Candida tenuis NRRL Y-1498 : CANTEDRAFT_103989 and Debaryomyces hansenii CBS767 : DEHA2F02046g || 1 0.26 0.35 0.52 0.52 0.21 -0.09 0.01 0.73 0.53 0.48 0.51 0.72 0.40 0.44 -0.16 0.80
2796 || orf19.1970 || || || Putative vacuole biogenesis protein || 1 0.20 0.11 0.39 0.13 0.04 -0.14 0.12 0.23 0.32 0.27 0.37 0.44 0.42 0.13 0.15 0.24
2797 || orf19.6286 || || || Ortholog(s) have role in vacuolar transport and endosome localization || 1 0.24 0.54 0.46 0.90 0.32 -0.62 0.47 1.01 0.43 0.47 0.81 0.88 0.90 0.81 0.57 0.39
2798 || orf19.5343 || ASH1 || || GATA-like transcription factor; localizes to daughter cell, hyphal tip cell nuclei; mRNA localization mediated by She3; required for WT virulence and filamentous growth on solid media; Ras1 repressed in yeast, Cyr1 repressed yeast, hyphae || 1 0.04 0.18 0.20 0.19 0.10 -0.16 0.38 0.59 0.44 0.36 0.42 0.69 1.13 0.78 0.34 0.24
2799 || orf19.3296 || || || Ortholog of C. dubliniensis CD36 : Cd36_01020, C. parapsilosis CDC317 : CPAR2_110130, Candida tenuis NRRL Y-1498 : CANTEDRAFT_93515 and Debaryomyces hansenii CBS767 : DEHA2D14542g || 1 0.41 0.28 0.33 0.18 0.05 -0.54 1.48 0.66 0.64 1.12 0.87 0.83 0.93 1.22 0.29 1.19
2800 || orf19.1622 || YCG1 || || Putative condensin G || 1 0.81 0.71 0.28 0.31 0.15 -0.38 0.69 0.41 0.75 1.29 1.81 0.60 0.81 1.51 -0.40 0.95
2801 || orf19.426 || || || Ortholog of C. dubliniensis CD36 : Cd36_05120, C. parapsilosis CDC317 : CPAR2_107740, Candida tenuis NRRL Y-1498 : CANTEDRAFT_136277 and Debaryomyces hansenii CBS767 : DEHA2A02266g || 1 0.35 0.50 0.26 0.01 0.29 -0.03 0.36 0.43 0.33 0.28 0.72 0.34 0.55 0.65 -0.11 0.39
2802 || orf19.3048 || || || Protein of unknown function; repressed by alpha pheromone in SpiderM medium || 1 0.26 0.50 0.29 0.22 0.18 -0.15 0.62 0.86 0.52 0.58 0.79 0.65 0.82 0.83 -0.16 0.26
2803 || orf19.1049 || || || Predicted NUDIX hydrolase domain; Hap43-induced || 1 0.22 0.32 0.51 0.47 0.24 0.11 0.15 0.70 0.70 1.10 1.27 0.65 1.37 0.88 -0.09 0.70
2804 || orf19.4620 || TIM12 || || Predicted component of the TIM22 complex, involved in protein import into mitochondrial inner membrane; flow model biofilm induced || 1 -0.09 0.24 0.35 0.19 0.04 0.04 0.29 0.32 0.82 0.69 0.41 0.64 0.46 0.67 -0.26 0.46
2805 || orf19.3533 || || || Ortholog(s) have role in ascospore formation, mitochondrial respiratory chain complex assembly, positive regulation of transcription from RNA polymerase II promoter || 1 0.06 0.23 0.55 0.29 0.23 -0.03 0.35 0.57 0.84 1.04 0.43 0.59 0.44 1.14 0.06 0.34
2806 || orf19.3295 || || || Has domain(s) with predicted role in cell division, chromosome segregation and MIS12/MIND type complex localization || 1 0.02 0.20 0.51 0.49 -0.33 -0.12 0.83 0.55 0.28 0.38 0.35 0.49 0.94 0.80 -0.27 0.62
2807 || orf19.4091 || MED18 || || RNA polymerase II mediator complex subunit; rat catheter biofilm repressed || 1 0.07 -0.14 0.02 -0.02 0.27 -0.19 0.51 0.62 0.05 0.52 0.92 0.66 0.58 0.89 0.05 0.71
2808 || orf19.5523 || || || Ortholog of C. dubliniensis CD36 : Cd36_62780, C. parapsilosis CDC317 : CPAR2_601690, Candida tenuis NRRL Y-1498 : CANTEDRAFT_113271 and Debaryomyces hansenii CBS767 : DEHA2A06644g || 1 0.20 -0.05 0.38 0.12 0.81 -0.11 0.26 0.77 0.15 0.08 1.57 0.73 0.06 0.75 0.01 0.77
2809 || orf19.596.2 || DAD4 || || Subunit of the Dam1 (DASH) complex, which acts in chromosome segregation by coupling kinetochores to spindle microtubules || 1 -0.05 0.05 0.56 0.40 0.32 0.25 0.34 0.53 0.28 0.22 0.88 0.35 0.29 0.62 -0.33 0.35
2810 || orf19.2540 || SAS3 || || Similar to silencing proteins; increased transcription is observed upon fluphenazine treatment; rat catheter biofilm repressed || 1 0.03 -0.10 0.51 0.06 0.26 0.13 0.28 0.32 0.44 0.29 0.90 0.72 0.31 0.87 -0.11 0.77
2811 || orf19.3659 || || || Putative CTD phosphatase; role in dephosphorylation of RNA polymerase II C-terminal domain, transcription from RNA polymerase II promoter; flow model biofilm induced || 1 0.09 0.28 0.37 0.35 0.90 0.78 0.37 0.65 0.65 0.17 1.07 0.53 0.44 1.17 0.18 0.89
2812 || orf19.2540 || SAS3 || || Similar to silencing proteins; increased transcription is observed upon fluphenazine treatment; rat catheter biofilm repressed || 1 0.00 0.13 0.32 -0.01 0.69 0.38 0.80 0.67 0.30 0.25 0.95 0.75 0.89 0.71 0.01 1.29
2813 || orf19.229 || || || Ortholog(s) have ubiquitin-protein ligase activity, role in protein ubiquitination involved in ubiquitin-dependent protein catabolic process and chromosome, centromeric region, mitotic spindle pole body, nucleus localization || 1 0.11 0.02 0.29 -0.31 0.11 0.37 0.54 0.68 0.27 -0.11 1.03 0.72 0.42 0.38 0.25 1.22
2814 || orf19.2278 || || || Putative 20S proteasome assembly protein; filament induced; induced by alpha pheromone in SpiderM medium || 1 0.39 0.06 -0.05 0.17 0.05 -0.16 0.33 0.77 -0.10 0.09 0.91 0.65 0.12 -0.12 0.26 0.31
2815 || orf19.7097 || || || Putative cytoplasmic RNA-binding protein; heterozygous null mutant exhibits hypersensitivity to parnafungin and cordycepin in C. albicans fitness test; Spider biofilm repressed || 1 0.50 0.44 -0.09 0.16 0.47 -0.46 0.41 0.98 -0.16 0.43 1.36 0.91 0.17 -0.05 0.46 0.48
2816 || orf19.7353 || || || Ortholog(s) have plus-end-directed microtubule motor activity, tubulin-dependent ATPase activity || 1 0.61 0.27 -0.11 0.36 0.41 -0.09 0.41 1.15 0.09 0.40 1.24 1.07 0.92 0.50 -0.14 0.84
2817 || orf19.4068 || || || Protein of unknown function; flow model biofilm induced || 1 -0.03 0.14 -0.02 0.07 0.13 -0.74 0.33 0.59 0.01 0.12 1.34 0.89 1.15 0.38 -0.04 0.50
2818 || orf19.2610 || || || Putative tRNA binding protein; intron-containing gene; Spider biofilm induced || 1 -0.14 -0.38 -0.13 0.25 0.30 -0.41 0.40 0.68 0.25 0.15 0.77 0.57 0.38 0.32 0.01 0.37
2819 || orf19.6931 || || || Putative cleavage factor I subunit; heterozygous null mutant exhibits hypersensitivity to parnafungin and cordycepin in the C. albicans fitness test || 1 -0.07 0.05 -0.15 0.09 0.28 -0.20 0.08 0.35 0.45 0.62 0.47 0.54 -0.14 0.56 0.00 0.25
2820 || orf19.234 || PHA2 || || Putative prephenate dehydratase; Hap43p-repressed gene; expression downregulated in an ssr1 null mutant || 1 -0.00 -0.20 -0.08 0.13 -0.10 -0.41 0.38 0.69 0.56 1.11 0.29 0.93 -0.13 0.55 0.26 0.30
2821 || orf19.1400 || || || Ortholog of C. dubliniensis CD36 : Cd36_23640, C. parapsilosis CDC317 : CPAR2_406130, Candida tenuis NRRL Y-1498 : CANTEDRAFT_116273 and Debaryomyces hansenii CBS767 : DEHA2B11176g || 1 0.13 0.07 0.03 -0.15 0.08 -0.25 0.17 0.30 0.38 0.24 0.24 0.07 0.16 0.19 0.22 0.31
2822 || orf19.5243 || TRP3 || || Putative bifunctional enzyme with predicted indole-3-glycerol-phosphate synthase and anthranilate synthase activities; regulated by Gcn2p and Gcn4p || 1 0.23 0.34 -0.01 -0.16 -0.06 -0.41 0.43 0.60 0.85 0.50 0.43 0.37 0.14 0.58 0.13 0.46
2823 || orf19.3763 || || || Has domain(s) with predicted serine-type endopeptidase activity and integral to membrane localization || 1 -0.17 -0.08 -0.10 0.05 -0.25 -0.44 0.93 0.73 1.03 0.80 0.69 0.64 0.57 0.57 0.68 0.63
2824 || orf19.1581 || || || Planktonic growth-induced gene || 1 0.09 0.10 -0.40 0.22 -0.13 -0.21 0.25 0.63 0.67 0.72 0.66 0.35 0.21 0.01 0.48 0.44
2825 || orf19.7401 || ISW2 || || Ortholog of S. cerevisiae Isw2; an ATPase involved in chromatin remodeling; required for chlamydospore formation; Hap43-induced gene; repressed by high-level peroxide stress || 1 -0.12 -0.23 -0.34 0.16 -0.31 -0.16 0.16 0.82 0.31 0.85 0.79 0.74 0.61 0.76 0.49 0.24
2826 || orf19.2558 || || || Has domain(s) with predicted zinc ion binding activity and nucleus localization || 1 0.04 0.12 -0.19 -0.25 -0.23 -0.09 0.53 0.26 0.46 0.62 0.94 0.73 0.38 0.92 0.21 0.26
2827 || orf19.5646 || || || Ortholog of S. cerevisiae : YPL034W, C. glabrata CBS138 : CAGL0L06996g, C. dubliniensis CD36 : Cd36_40280, C. parapsilosis CDC317 : CPAR2_402170 and Candida tenuis NRRL Y-1498 : CANTEDRAFT_137348 || 1 -0.20 0.15 -0.19 -0.12 -0.42 -0.14 0.00 0.09 0.23 0.47 1.04 1.04 0.28 0.65 0.33 0.72
2828 || orf19.4781 || GRP1 || || Protein similar to dihydroflavonol-4-reductases || 1 -0.30 -0.24 -0.10 -0.11 0.01 -0.47 0.22 -0.02 0.54 0.54 0.62 0.83 0.13 0.65 -0.20 0.83
2829 || orf19.6581 || || || Ortholog(s) have palmitoyltransferase activity, role in protein palmitoylation and endoplasmic reticulum localization || 1 -0.21 -0.01 -0.36 -0.40 0.11 -0.81 0.18 0.25 0.52 0.54 0.61 0.63 0.28 0.79 0.15 0.66
2830 || orf19.3780 || || || Protein likely to be essential for growth, based on an insertional mutagenesis strategy || 1 0.32 0.08 -0.56 -0.41 -0.17 -1.10 0.07 0.59 0.02 0.50 0.71 1.10 0.69 0.89 0.49 0.78
2831 || orf19.2760 || || || Putative mRNA cleavage and polyadenylation factor; heterozygous null mutant exhibits hypersensitivity to parnafungin and cordycepin in the C. albicans fitness test || 1 -0.17 -0.25 -0.03 0.11 -0.37 -0.31 0.18 0.53 0.43 0.40 0.47 0.16 0.48 0.44 -0.02 0.34
2832 || orf19.1113 || || || Ortholog of C. dubliniensis CD36 : Cd36_53540, Debaryomyces hansenii CBS767 : DEHA2G07854g, Pichia stipitis Pignal : PICST_32162 and Spathaspora passalidarum NRRL Y-27907 : SPAPADRAFT_50795 || 1 -0.29 0.29 -0.02 0.17 -0.64 -0.22 0.69 0.44 0.49 0.83 0.90 0.32 0.80 0.35 0.19 0.16
2833 || orf19.3471 || || || Protein with a predicted anaphase-promoting complex APC subunit 1 CDC26 domain; Hap43-repressed gene || 1 0.22 0.47 0.18 -0.15 -0.04 -0.12 1.25 0.48 -0.02 0.60 1.58 0.61 0.08 0.57 0.44 0.64
2834 || orf19.1204 || || || Phosphorylated protein of unknown function; transcript is upregulated clinical isolates from HIV positive patients with oral candidiasis || 1 -0.23 -0.19 -0.35 -0.35 0.21 0.21 0.55 -0.08 0.23 0.50 0.82 0.28 0.01 0.61 0.48 0.78
2835 || orf19.3825 || RCE1 || || Putative Type II CAAX prenyl protease; induced during the mating process || 1 -0.20 -0.19 -0.42 -0.14 -0.02 -0.12 0.59 0.55 0.47 -0.04 0.98 0.22 0.03 0.35 0.43 0.90
2836 || orf19.7610 || PTP3 || || Putative protein tyrosine phosphatase; hypha induced; alkaline induced; regulated by Efg1, Ras1, cAMP pathways; mutants are viable; Spider biofilm induced; rat catheter biofilm repressed; flow model biofilm repressed || 1 0.83 0.35 -0.49 -0.01 -0.21 -0.44 0.68 0.46 0.69 0.16 0.77 0.92 0.65 -0.12 0.62 -0.17
2837 || orf19.7610 || PTP3 || || Putative protein tyrosine phosphatase; hypha induced; alkaline induced; regulated by Efg1, Ras1, cAMP pathways; mutants are viable; Spider biofilm induced; rat catheter biofilm repressed; flow model biofilm repressed || 1 0.36 0.08 -0.97 -0.70 -0.36 -0.45 0.58 0.41 0.50 -0.01 0.86 1.04 0.56 0.14 0.46 0.08
2838 || orf19.3721 || || || Protein of unknown function; Spider biofilm induced || 1 0.23 0.43 -0.89 -0.74 -0.13 -0.77 1.06 0.76 0.75 -0.21 0.91 0.41 -0.22 0.21 0.32 -0.11
2839 || orf19.6864 || || || Putative ubiquitin-protein ligase; role in protein ubiquitination; Spider biofilm induced || 1 0.40 0.39 -0.56 -0.39 0.56 -0.48 1.11 1.00 0.86 0.47 0.93 1.41 -0.29 -0.27 0.46 -0.15
2840 || orf19.6864 || || || Putative ubiquitin-protein ligase; role in protein ubiquitination; Spider biofilm induced || 1 0.15 0.12 0.12 -1.17 0.33 -0.44 1.46 1.04 1.43 1.09 1.59 0.05 0.30 -0.94
2841 || orf19.520 || || || Ortholog of C. dubliniensis CD36 : Cd36_29660, C. parapsilosis CDC317 : CPAR2_205200, Candida tenuis NRRL Y-1498 : CANTEDRAFT_96118 and Debaryomyces hansenii CBS767 : DEHA2F21428g || 1 0.04 0.06 0.15 -0.04 -0.19 -0.07 0.56 0.30 0.17 0.15 0.12 0.63 0.31 0.58 0.21 0.28
2842 || orf19.3295 || || || Has domain(s) with predicted role in cell division, chromosome segregation and MIS12/MIND type complex localization || 1 0.19 0.04 0.10 0.16 -0.08 -0.15 0.20 0.20 -0.11 -0.18 0.48 0.72 0.32 0.60 0.26 0.58
2843 || orf19.2135 || TSM1 || || Putative transcription initiation factor TFIID subunit; transcript is upregulated in clinical isolates from HIV+ patients with oral candidiasis; Nrg1-regulated || 1 0.17 0.10 -0.01 -0.18 -0.11 -0.20 0.03 0.25 0.32 -0.25 0.44 0.40 0.05 0.33 0.40 0.19
2844 || orf19.2135 || TSM1 || || Putative transcription initiation factor TFIID subunit; transcript is upregulated in clinical isolates from HIV+ patients with oral candidiasis; Nrg1-regulated || 1 0.26 0.33 0.03 -0.16 0.06 -0.28 0.39 0.46 0.30 -0.18 0.39 0.33 0.34 0.36 0.55 0.02
2845 || orf19.1371 || || || Ortholog of C. dubliniensis CD36 : Cd36_23880, C. parapsilosis CDC317 : CPAR2_806590, Candida tenuis NRRL Y-1498 : CANTEDRAFT_92769 and Debaryomyces hansenii CBS767 : DEHA2B13376g || 1 0.01 0.17 0.22 -0.10 0.10 -0.26 0.40 0.78 0.21 -0.13 0.38 0.41 0.32 0.52 0.26 0.11
2846 || orf19.2650 || || || Protein of unknown function; rat catheter biofilm induced || 1 0.08 0.05 0.49 -0.22 0.34 0.07 0.59 0.44 0.10 -0.28 0.57 0.58 0.39 0.50 0.90 0.77
2847 || orf19.4339 || VPS4 || || AAA-ATPase involved in transport from MVB to the vacuole and ESCRT-III complex disassembly; mutation decreases SAP secretion and virulence in murine intravenous infection; regulated by Gcn2p, Gcn4p; required for normal Rim8p processing || 1 0.10 0.16 0.04 -0.30 0.05 -0.28 0.41 0.34 0.00 -0.20 0.61 0.44 0.64 0.16 0.84 0.79
2848 || orf19.4339 || VPS4 || || AAA-ATPase involved in transport from MVB to the vacuole and ESCRT-III complex disassembly; mutation decreases SAP secretion and virulence in murine intravenous infection; regulated by Gcn2p, Gcn4p; required for normal Rim8p processing || 1 0.35 0.12 0.30 -0.14 -0.14 -0.37 0.37 0.22 0.01 -0.22 0.36 0.43 0.24 0.23 0.66 0.50
2849 || orf19.5145 || SSP96 || || Putative flavin-containing monooxygenase; F-12/CO2 early biofilm induced || 1 0.15 -0.06 0.08 -0.01 -0.32 -0.39 0.47 0.03 0.25 -0.24 0.37 0.45 0.38 -0.08 0.58 0.65
2850 || orf19.2040 || || || Ortholog(s) have oxidoreductase activity, acting on NAD(P)H activity, role in iron-sulfur cluster assembly, nitric oxide biosynthetic process, oxidation-reduction process and mitochondrion localization || 1 0.20 0.13 -0.04 -0.12 -0.17 0.05 0.23 0.32 0.48 0.43 0.23 0.57 0.63 -0.11 0.25 0.30
2851 || orf19.3780 || || || Protein likely to be essential for growth, based on an insertional mutagenesis strategy || 1 0.21 0.23 -0.33 -0.44 -0.61 0.24 0.74 0.59 0.55 0.92 0.47 1.11 1.32 -0.20 -0.01
2852 || orf19.6858 || EDC3 || || Ortholog(s) have role in cytoplasmic mRNA processing body assembly, deadenylation-independent decapping of nuclear-transcribed mRNA and cytoplasmic mRNA processing body localization || 1 -0.09 -0.04 0.23 -0.33 -0.08 0.07 0.50 -0.07 0.11 0.66 0.45 0.43 0.56 0.19 0.08 0.49
2853 || orf19.7564 || DPB2 || || Probable subunit of DNA polymerase II (DNA polymerase epsilon), similar to S. cerevisiae Dpb2p; essential for viability; rat catheter biofilm induced || 1 0.20 0.28 0.46 0.29 -0.00 -0.18 -0.03 0.42 0.15 0.64 1.13 0.38 0.66 0.17 -0.21 0.13
2854 || orf19.3048 || || || Protein of unknown function; repressed by alpha pheromone in SpiderM medium || 1 0.27 0.03 0.16 0.44 -0.11 -0.26 0.76 0.71 0.20 0.55 0.45 0.31 0.68 0.21 -0.34 0.07
2855 || orf19.4952.1 || || || Ortholog(s) have FK506 binding, Hsp70 protein binding, chaperone binding, peptidyl-prolyl cis-trans isomerase activity, role in protein complex assembly and cytoplasm, nucleus localization || 1 -0.02 0.24 0.08 0.23 -0.02 -0.14 0.35 0.71 0.87 0.43 0.57 0.46 0.26 0.22 -0.41 0.17
2856 || orf19.2081 || POM152 || || Putative nuclear pore membrane glycoprotein || 1 0.27 0.27 0.14 -0.08 0.44 -0.12 0.01 0.50 0.38 0.68 0.44 0.42 -0.13 0.41 -0.20 0.34
2857 || orf19.2465 || POL32 || || Putative subunit of DNA polymerase delta, involved in chromosomal DNA replication; cell-cycle regulated periodic mRNA expression || 1 -0.10 -0.11 0.56 0.09 0.44 0.02 0.44 0.64 0.56 1.04 0.63 0.31 -0.13 0.98 -0.42 0.50
2858 || orf19.794 || SSN3 || || Putative cyclin-dependent protein kinase; mutants are sensitive to growth on H2O2 medium || 1 0.21 0.07 0.35 0.24 0.02 0.21 0.20 0.04 0.31 0.38 0.41 -0.29 0.14 0.44 0.06 0.12
2859 || orf19.3536 || || || Ortholog(s) have acetylglucosaminyltransferase activity, role in protein N-linked glycosylation and Golgi medial cisterna localization || 1 0.34 0.40 0.62 0.51 0.47 -0.48 0.27 0.43 0.80 1.03 0.52 -0.40 0.10 0.66 -0.07 0.12
2860 || orf19.6909 || || || Ortholog(s) have TFIIH-class transcription factor binding, TFIIH-class transcription factor recruiting transcription factor activity || 1 0.47 0.30 0.09 0.03 0.47 -0.09 0.77 0.97 1.35 1.08 1.17 -0.15 0.36 0.84 0.31 0.35
2861 || orf19.4280 || || || Protein of unknown function; Spider biofilm induced; rat catheter biofilm repressed || 1 1.04 -0.34 0.33 0.49 0.80 0.72 0.94 1.57 1.37 1.09 0.86 -0.35 1.15 0.75 0.34 0.51
2862 || orf19.6041 || RPO41 || || Putative mitochondrial RNA polymerase; repressed in core stress response; Spider biofilm induced || 1 -0.09 -0.21 0.00 0.04 0.20 0.12 0.40 0.60 0.12 0.81 0.17 -0.12 0.41 0.30 -0.00 -0.25
2863 || orf19.2078 || || || Ortholog(s) have role in Golgi to vacuole transport and AP-1 adaptor complex localization || 1 0.11 0.24 -0.05 0.14 0.78 -0.62 0.44 0.66 0.21 -0.13 0.68 0.05 0.17 0.44 -0.02 0.34
2864 || orf19.4441 || || || Ortholog(s) have DNA replication origin binding, double-stranded DNA binding, single-stranded DNA binding activity || 1 0.16 0.32 0.13 -0.02 0.63 -0.16 0.56 0.20 0.12 -0.04 0.69 0.25 0.06 0.46 0.13 0.19
2865 || orf19.5003 || || || Ortholog(s) have GTPase regulator activity and cytoplasm, nuclear envelope localization || 1 0.05 0.03 0.19 -0.34 0.57 0.14 0.58 0.44 0.31 -0.43 0.47 0.25 0.15 0.50 0.07 0.37
2866 || orf19.2283 || DQD1 || || Putative 3-dehydroquinate dehydratase; ketoconazole-repressed; protein abundance downregulated by macrophages; flow model biofilm induced || 1 0.25 0.22 -0.08 -0.14 0.36 -0.23 0.92 0.86 0.58 -0.69 1.03 0.34 -0.04 0.37 0.17 0.72
2867 || orf19.796 || HYM1 || || Protein of RAM cell wall integrity signaling network; involved in regulation of Ace2 activity and cellular morphogenesis; role in cell separation, azole sensitivity; required for hyphal growth || 1 0.10 0.36 0.17 -0.23 0.03 -0.17 0.46 0.21 0.44 -0.11 0.46 0.06 -0.12 0.49 -0.01 0.73
2868 || orf19.2196 || || || Ortholog(s) have ubiquitin binding activity and cytoplasm localization || 1 0.08 0.18 0.31 -0.06 0.22 0.05 0.68 0.26 0.72 0.09 0.55 0.34 0.08 0.68 0.30 0.63
2869 || orf19.4928 || SEC2 || || Guanyl-nucleotide exchange factor for the small G-protein Sec4; delivery of post-Golgi secretory vesicles to sites of polarized growth; phosphorylation by Cdc28 needed for normal hyphal growth; Hap43-repressed; flow model biofilm induced || 1 0.12 1.22 -0.20 -0.26 0.82 0.39 1.22 0.60 0.69 0.16 0.39 0.26 0.75 0.47 0.25 0.92
2870 || orf19.6511 || LIG1 || || tRNA ligase; functional homolog of S. cerevisiae Trl1 || 1 0.50 0.73 0.04 -0.21 0.92 0.30 0.91 0.50 0.87 -0.29 0.39 -0.06 0.59 0.04 -0.10 0.44
2871 || orf19.3820 || || || Protein with DNA binding domain, an endonuclease domain; adjacent to CEN4, the centromere region of Chr 4; clade-associated gene expression || 1 0.98 0.78 0.31 -0.01 0.48 0.47 0.72 0.76 1.17 -0.34 0.41 -0.19 1.34 0.43 -0.18 0.84
2872 || orf19.2866 || || || Has domain(s) with predicted DNA binding activity || 1 1.00 0.69 0.71 -0.02 0.55 0.65 0.82 1.01 1.08 0.01 0.58 0.30 1.40 0.71 -0.04 1.28
2873 || orf19.2866 || || || Has domain(s) with predicted DNA binding activity || 1 0.39 0.75 0.47 -0.34 0.31 0.42 0.76 0.80 0.92 -0.10 0.37 0.03 1.28 0.47 -0.29 1.19
2874 || orf19.3820 || || || Protein with DNA binding domain, an endonuclease domain; adjacent to CEN4, the centromere region of Chr 4; clade-associated gene expression || 1 0.55 0.92 0.29 -0.13 0.43 0.67 0.93 0.74 1.35 -0.02 0.48 0.61 1.41 0.11 -0.23 1.07
2875 || orf19.2866 || || || Has domain(s) with predicted DNA binding activity || 1 0.69 0.79 0.00 -0.74 0.45 0.56 1.34 1.13 1.02 -0.36 0.76 0.46 1.39 0.88 -0.10 1.29
2876 || orf19.3820 || || || Protein with DNA binding domain, an endonuclease domain; adjacent to CEN4, the centromere region of Chr 4; clade-associated gene expression || 1 0.43 0.76 -0.08 -0.74 0.47 0.36 1.31 1.04 0.79 -0.32 0.70 0.35 1.57 0.71 -0.29 0.90
2877 || orf19.1200 || || || Protein of unknown function; Spider biofilm induced || 1 0.05 0.20 0.40 0.07 -0.02 0.24 0.55 0.71 0.62 -0.12 0.40 0.40 0.96 0.57 0.26 1.05
2878 || orf19.1434 || || || Ortholog(s) have protein kinase activator activity || 1 0.18 0.27 0.11 -0.39 0.24 -0.22 0.87 0.48 0.38 -0.20 0.31 -0.03 0.77 0.13 -0.39 1.08
2879 || orf19.3820 || || || Protein with DNA binding domain, an endonuclease domain; adjacent to CEN4, the centromere region of Chr 4; clade-associated gene expression || 1 0.39 0.47 -0.28 -0.71 -0.04 0.09 1.04 0.76 0.46 -0.63 0.27 -0.04 1.29 0.24 -0.57 0.88
2880 || orf19.2866 || || || Has domain(s) with predicted DNA binding activity || 1 0.15 0.55 -0.44 -0.81 0.05 0.08 0.96 0.72 0.47 -0.69 0.34 -0.15 1.35 0.15 -0.61 0.59
2881 || orf19.3820 || || || Protein with DNA binding domain, an endonuclease domain; adjacent to CEN4, the centromere region of Chr 4; clade-associated gene expression || 1 0.19 0.24 0.21 -0.27 0.08 0.39 0.18 0.37 0.67 -0.53 0.05 0.16 0.94 0.35 -0.43 0.74
2882 || orf19.5177 || || || Ortholog of Candida albicans WO-1 : CAWG_05627 || 1 0.41 0.42 -0.10 -0.22 0.41 0.04 0.26 0.24 0.71 -0.49 -0.05 -0.09 0.45 0.42 -0.41 0.37
2883 || orf19.4305.1 || || || Ortholog(s) have RNA binding activity, role in mRNA splicing, via spliceosome and U4/U6 x U5 tri-snRNP complex, U6 snRNP, nucleolus localization || 1 -0.02 -0.03 -0.20 -0.13 0.07 0.06 0.51 0.66 0.41 -0.09 -0.05 -0.05 0.13 0.70 -0.52 0.19
2884 || orf19.5078 || || || Protein of unknown function; Hap43-repressed gene; rat catheter biofilm repressed || 1 0.12 0.23 -0.35 -0.84 -0.34 -0.18 1.54 1.26 0.67 -0.47 0.62 0.11 0.48 0.45 -0.52 0.21
2885 || orf19.5078 || || || Protein of unknown function; Hap43-repressed gene; rat catheter biofilm repressed || 1 0.25 0.30 -0.11 -0.47 -0.25 -0.02 0.98 0.86 0.70 -0.38 0.47 0.28 0.41 0.57 -0.21 0.20
2886 || orf19.7551 || ALO1 || || D-Arabinono-1,4-lactone oxidase involved in biosynthesis of dehydro-D-arabinono-1,4-lactone, which has a protective role against oxidative damage; plasma membrane-localized;required for full virulence in a mouse model of systemic infection || 1 0.45 0.45 -0.47 -0.68 0.12 0.07 0.71 0.67 0.59 0.01 0.25 0.11 0.33 0.67 -0.02 0.56
2887 || orf19.5136 || || || Putative pyridoxamine 5'-phosphate oxidase; planktonic growth and early-stage flow model biofilm induced || 1 0.77 0.22 -0.26 -0.10 -0.40 -0.12 0.30 0.64 0.75 -0.44 0.58 0.11 0.38 0.56 -1.01 0.92
2888 || orf19.4013 || || || Putative protein of unknown function; Hap43p-repressed gene; S. cerevisiae ortholog YHR045W localizes to the endoplasmic reticulum || 1 0.53 0.11 -0.23 -0.05 -0.46 -0.33 0.61 0.90 0.95 -0.18 0.37 0.18 0.85 0.62 -0.41 0.90
2889 || orf19.1077 || ATM1 || || Member of MDR subfamily of ABC family; ortholog of S. cerevisiae ABC transporter, Atm1; induced in low iron; induced by nitric oxide independent of Yhb1 || 1 0.30 0.27 -0.26 0.03 -0.37 -0.56 0.97 0.53 0.98 -0.16 0.42 0.41 0.19 0.92 0.27 0.68
2890 || orf19.7244 || || || Putative fumarylacetoacetate hydrolase; induced by nitric oxide independent of Yhb1; regulated by Sef1, Sfu1, Hap43; flow model biofilm induced || 1 0.14 0.01 -0.43 -0.18 -0.51 -1.07 0.92 0.62 0.92 -0.31 0.27 0.32 0.13 0.59 -0.55 0.50
2891 || orf19.6755 || DLD2 || || Ortholog(s) have D-lactate dehydrogenase (cytochrome) activity, role in aerobic respiration, cellular carbohydrate metabolic process and mitochondrial inner membrane localization || 1 -0.11 -0.23 -0.12 -0.08 -0.37 -0.58 0.47 0.45 0.54 -0.19 0.08 0.45 0.23 0.15 -0.12 0.34
2892 || orf19.3173 || || || Ortholog(s) have Golgi apparatus, endoplasmic reticulum localization || 1 0.06 0.12 0.09 0.52 -0.05 -0.31 0.22 0.30 0.19 0.31 0.10 0.68 0.18 -0.16 -0.02 0.34
2893 || orf19.3846 || LYS4 || || Homoaconitase; regulated by Gcn4, Gcn2; induced in response to amino acid starvation (3-AT); induced by human whole blood or PMNs; Hap43-repressed; flow model and Spider biofilm repressed || 1 0.04 0.14 0.41 1.07 -0.43 -0.37 0.95 1.08 1.46 0.78 0.33 0.73 -0.38 -0.49 0.17 0.33
2894 || orf19.1832 || FCY23 || || Putative transporter; Gcn4p-regulated; more similar to S. cerevisiae Tpn1p, which is a vitamin B6 transporter, than to purine-cytosine permeases || 1 0.18 0.46 0.38 0.37 0.15 -0.59 0.41 0.24 1.31 0.25 0.41 0.73 0.48 0.04 0.17 -0.14
2895 || orf19.7339 || BGL22 || || Putative glucanase; induced during cell wall regeneration || 1 0.20 0.47 0.89 0.57 -0.47 -1.29 0.13 0.01 1.02 0.46 0.46 0.56 0.09 0.18 0.45 0.01
2896 || orf19.3065 || DAO1 || || Putative D-amino acid oxidase; transcription is regulated upon yeast-hyphal switch || 1 0.10 0.22 -0.18 0.01 0.16 -0.67 0.03 0.48 0.71 0.29 0.04 0.35 -0.07 -0.13 0.28 -0.17
2897 || orf19.3063 || HFL1 || || HAP5-like; ortholog of S. cerevisiae Dpb3; third-largest subunit of DNA polymerase II (DNA polymerase epsilon); phosphorylated protein; mutants have a growth defect || 1 -0.18 -0.09 -0.15 0.19 0.55 -0.72 0.15 0.54 0.21 0.65 0.12 0.43 -0.17 0.44 -0.05 0.09
2898 || orf19.234 || PHA2 || || Putative prephenate dehydratase; Hap43p-repressed gene; expression downregulated in an ssr1 null mutant || 1 0.00 0.23 -0.30 0.33 -0.19 -0.45 0.61 0.79 0.20 0.63 -0.04 0.68 -0.04 0.38 0.17 0.28
2899 || orf19.4719 || CWH41 || || Processing alpha glucosidase I, involved in N-linked protein glycosylation and assembly of cell wall beta 1,6 glucan; rat catheter biofilm repressed || 1 0.24 0.33 -0.07 0.06 -0.32 -0.57 0.59 0.47 0.59 0.46 0.63 0.62 -0.43 0.24 -0.02 0.71
2900 || orf19.4603 || ARL1 || || Putative GTPase; mutation confers dose-dependent sensitivity to Brefeldin A || 1 0.09 0.02 0.29 0.61 -0.66 -0.78 0.06 0.56 0.20 0.72 0.90 0.73 -0.22 0.14 -0.04 0.40
2901 || orf19.5768 || SNF4 || || Transcription factor; ortholog of S. cerevisiae Snf4; caspofungin repressed; transposon mutation affects filamentation || 1 -0.14 -0.18 0.06 0.38 -0.45 -0.33 0.05 0.58 0.08 0.16 0.71 0.34 -0.46 0.53 0.07 0.38
2902 || orf19.7588 || || || Ortholog(s) have mitochondrion localization || 1 -0.22 -0.48 -0.05 0.14 -0.23 -1.07 0.77 1.25 -0.26 0.44 0.66 0.44 -0.17 0.69 -0.32 0.33
2903 || orf19.967 || || || Major mitochondrial nuclease; has RNAse and DNA endo- and exonucleolytic activities; roles in mitochondrial recombination, apoptosis and maintenance of polyploidy; Spider biofilm repressed || 1 0.04 0.05 0.09 -0.05 -0.10 -0.68 0.46 0.86 0.19 0.56 0.59 0.17 -0.15 -0.15 -0.54 0.30
2904 || orf19.5640 || PEX5 || || Pex5p family protein; required for PTS1-mediated peroxisomal protein import, fatty acid beta-oxidation; similar to S. cerevisiae Pas10p peroxisomal targeting receptor; macrophage/pseudohyphal-repressed; Hap43p-repressed || 1 -0.09 -0.05 0.14 0.44 0.09 -0.77 -0.03 0.15 -0.09 0.09 0.44 0.17 -0.36 0.23 -0.03 0.45
2905 || orf19.5056 || || || Ortholog(s) have enzyme regulator activity, mitotic anaphase-promoting complex activity || 1 0.13 0.08 0.29 -0.03 -0.33 -0.91 0.34 0.08 -0.19 0.47 0.08 0.22 -0.13 0.08 -0.32 0.49
2906 || orf19.793 || CAK1 || || Monomeric CDK-activating kinase; functional homolog of S. cerevisiae Cak1p; phosphorylates cyclin-free human CDK2; lacks glycine loop motif; conserved lysine (K36) not required for activity; possibly essential gene (by UAU1 method) || 1 0.46 0.35 -0.08 0.04 -0.04 -0.21 0.02 0.51 -0.28 -0.01 0.18 0.14 0.10 0.24 -0.14 0.27
2907 || orf19.6780 || MET8 || || Putative bifunctional dehydrogenase and ferrochelatase with a predicted role in siroheme biosynthesis; regulated by Gcn2p and Gcn4p || 1 0.50 0.40 -0.19 0.12 0.36 -0.44 0.20 0.66 -0.12 0.26 0.45 0.25 0.51 0.31 0.06 0.30
2908 || orf19.6851 || CHL4 || || Protein described as having role in chromosome segregation; RNA abundance regulated by tyrosol and cell density || 1 1.12 0.43 -0.05 0.17 1.18 -0.58 0.32 0.81 -0.06 0.60 0.62 0.44 0.61 0.14 -0.06 0.25
2909 || orf19.2709 || ZUO1 || || Ortholog of S. cerevisiae Zuo1; a cytosolic ribosome-associated chaperone; likely to be essential for growth, based on an insertional mutagenesis strategy; Spider biofilm repressed || 1 0.62 0.47 -0.13 -0.24 0.14 -0.33 -0.02 0.26 -0.05 0.53 0.25 0.08 0.15 0.02 -0.23 0.36
2910 || orf19.3904 || MRV4 || || Protein of unknown function; Spider biofilm induced || 1 0.89 0.82 0.80 -0.01 0.23 0.41 0.18 1.09 0.72 0.79 0.07 0.07 -0.10 0.95
2911 || orf19.5859 || DAL8 || || Putative allantoate permease; fungal-specific (no human or murine homolog) || 1 0.97 1.25 0.11 0.40 0.47 -1.40 0.46 0.30 0.76 0.64 0.62 0.20 0.00 -0.52 0.71
2912 || orf19.4711 || || || Ortholog of C. dubliniensis CD36 : Cd36_40890, C. parapsilosis CDC317 : CPAR2_401100, Candida tenuis NRRL Y-1498 : CANTEDRAFT_119698 and Debaryomyces hansenii CBS767 : DEHA2G22154g || 1 0.27 0.16 0.17 0.09 0.20 -0.21 0.04 -0.03 0.11 0.20 0.16 0.19 -0.13 -0.05 0.20 0.38
2913 || orf19.6475 || || || Protein of unknown function; flow model biofilm induced || 1 0.71 0.22 0.50 0.14 0.24 -0.52 -0.17 0.16 0.39 -0.09 0.04 0.31 -0.31 0.40 0.47
2914 || orf19.6324 || VID27 || || Protein similar to S. cerevisiae Vid27p; transposon mutation affects filamentous growth; mutation confers hypersensitivity to toxic ergosterol analog; fungal-specific (no human or murine homolog) || 1 0.04 0.16 0.08 0.12 -0.04 -0.39 -0.23 0.06 -0.04 0.05 -0.01 -0.01 -0.32 -0.01 0.55 0.38
2915 || orf19.6674 || BTS1 || || Putative geranylgeranyl diphosphate synthase; repressed by benomyl treatment; Spider biofilm induced || 1 0.43 0.01 0.42 0.48 0.04 -0.48 -0.03 0.50 0.00 0.12 0.18 0.12 -0.11 -0.18 0.86 0.82
2916 || orf19.3242 || || || Putative TFIID and SAGA complex subunit; possibly an essential gene, disruptants not obtained by UAU1 method || 1 0.58 0.16 0.18 0.01 0.12 -0.02 0.21 0.85 -0.36 0.32 0.32 0.35 -0.16 -0.06 0.68 0.28
2917 || orf19.2230 || || || Putative pre-mRNA-splicing factor; decreased transcription is observed upon benomyl treatment || 1 0.26 0.00 0.00 0.27 0.04 -0.36 -0.02 0.49 -0.35 0.32 0.39 0.39 -0.42 -0.09 0.23 0.27
2918 || orf19.1336 || PUP3 || || Putative beta 3 subunit of the 20S proteasome; macrophage/pseudohyphal-repressed || 1 0.54 0.58 0.07 0.33 -0.64 -0.34 0.03 0.53 0.11 0.16 0.43 0.27 -0.46 0.12 0.41 0.25
2919 || orf19.213 || || || Ortholog(s) have role in ubiquitin-dependent protein catabolic process and nucleus, proteasome regulatory particle, lid subcomplex, proteasome storage granule localization || 1 0.87 0.71 0.20 0.20 -0.46 -0.69 0.22 0.59 -0.08 0.34 0.86 0.38 -0.35 0.01 0.64 0.58
2920 || orf19.4715 || || || Ortholog(s) have tubulin binding activity, role in microtubule cytoskeleton organization, mitochondrial fission, mitochondrion inheritance, nuclear migration along microtubule and cell cortex, cellular bud tip, mitochondrion localization || 1 0.60 0.58 0.36 0.18 -0.13 -0.47 0.03 0.24 0.00 0.44 0.46 0.27 -0.01 0.41 0.22 0.64
2921 || orf19.4208 || RAD52 || || Required for homologous DNA recombination, repair of UV- or MMS-damaged DNA, telomere length, UV-induced LOH; constitutive expression, MMS-induced; weakly complements S. cerevisiae rad52 mutant; slow growth, increased white-to-opaque switch || 1 0.69 0.40 0.33 0.18 -0.05 -0.79 -0.06 0.64 0.08 0.42 0.65 0.55 -0.03 0.15 0.07 0.78
2922 || orf19.6272 || || || Putative ubiquitin C-terminal hydrolase; regulated by Gcn2p and Gcn4p || 1 0.61 0.39 0.21 0.45 -0.20 -0.44 0.12 0.29 -0.02 0.18 0.48 0.43 0.09 0.81 0.56 0.37
2923 || orf19.6272 || || || Putative ubiquitin C-terminal hydrolase; regulated by Gcn2p and Gcn4p || 1 0.87 0.75 0.05 0.21 -0.02 -0.53 0.08 0.24 -0.23 -0.27 0.83 0.66 -0.06 0.31 0.89 0.66
2924 || orf19.6039 || || || Ortholog(s) have SNAP receptor activity and role in ER to Golgi vesicle-mediated transport, Golgi organization, intra-Golgi vesicle-mediated transport, vesicle fusion with Golgi apparatus || 1 0.48 0.40 0.42 0.13 0.07 -0.18 -0.05 0.18 -0.28 0.18 0.55 0.53 -0.02 -0.22 0.51 0.28
2925 || orf19.4413 || CMD1 || || Calmodulin; calmodulin inhibitors cause a defect in hyphal growth; transcript not regulated by yeast-hyphal transition; mutation confers hypersensitivity to cytochalasin D and high concentrations of tunicamycin; gene has intron || 1 0.43 0.41 0.42 0.26 0.04 -0.18 0.09 0.43 -0.24 0.02 0.71 0.20 -0.14 -0.09 0.16 0.23
2926 || orf19.2549 || SHP1 || || Regulator of the type 1 protein phosphatase Glc7p activity, involved in control of morphogenesis, progression through the cell cycle and response to DNA damage || 1 0.74 0.58 -0.21 -0.45 0.27 -0.46 0.63 0.75 0.13 0.17 0.99 0.13 -0.10 -0.13 0.88 0.71
2927 || orf19.121 || ARC18 || || Putative ARP2/3 complex subunit; mutation confers hypersensitivity to cytochalasin D || 1 0.78 0.64 0.08 -0.19 0.50 -0.19 0.19 0.79 -0.24 -0.07 0.94 0.16 -0.26 -0.11 0.73 0.48
2928 || orf19.3661 || || || Putative deubiquitinating enzyme; induced by Mnl1 under weak acid stress || 1 0.62 0.46 0.03 0.10 0.29 -0.24 0.17 0.63 0.31 -0.11 1.36 0.63 -0.82 -0.03 0.47 0.58
2929 || orf19.1776 || || || Putative pantetheine-phosphate adenylyltransferase (PPAT); which catalyzes 4th step in coenzyme A biosynthesis from pantothenate; rat catheter biofilm repressed || 1 0.19 0.19 -0.25 -0.21 -0.03 -0.35 -0.01 0.78 0.14 -0.08 0.74 0.42 -0.30 0.27 0.66 0.58
2930 || orf19.1136 || || || Ortholog(s) have AP-2 adaptor complex, cytosol, nucleus localization || 1 0.23 0.08 -0.20 -0.38 -0.17 -0.91 -0.04 0.54 0.30 -0.02 0.80 0.40 -0.40 0.03 0.22 0.63
2931 || orf19.3251 || ARC19 || || Putative ARP2/3 complex subunit; Hap43-induced gene; mutation confers hypersensitivity to cytochalasin D; rat catheter biofilm repressed || 1 0.51 0.24 -0.18 -0.12 -0.37 -0.36 0.53 0.43 -0.12 0.05 0.47 0.19 -0.22 0.16 0.18 0.67
2932 || orf19.213 || || || Ortholog(s) have role in ubiquitin-dependent protein catabolic process and nucleus, proteasome regulatory particle, lid subcomplex, proteasome storage granule localization || 1 0.50 0.53 0.00 0.09 -0.39 -0.40 0.11 -0.06 -0.68 -0.23 0.48 0.43 -0.29 -0.31 0.81 0.59
2933 || orf19.1236 || GVP36 || || BAR domain protein; ocalizes to early and late Golgi vesicles; predicted role in adaptation to varying nutrient concentrations, fluid-phase endocytosis, actin cytoskeleton polarization and vacuole biogenesis; rat catheter biofilm repressed || 1 0.54 0.66 -0.32 0.50 0.43 0.30 -0.41 -0.00 -0.26 0.26 0.09 0.22 0.12 -0.05 0.00 0.13
2934 || orf19.4874 || MNN23 || || Alpha-1,2-mannosyltransferase; mutants hypersensitive to toxic ergosterol analog, amphotericin B, calcofluor white, growth at 42 degrees and have decreased cell wall mannan; flow model biofilm induced || 1 0.39 0.34 0.15 0.52 0.44 0.38 -0.17 0.17 -0.35 -0.01 0.10 0.05 0.22 0.27 -0.09 0.21
2935 || orf19.4353 || ULP2 || || SUMO deconjugation enzyme; removes the small ubiquitin-like modifier (SUMO) from proteins; Spider biofilm induced || 1 0.74 0.81 0.37 0.27 0.34 0.38 0.10 0.04 0.04 -0.37 0.51 0.59 0.36 0.23 0.04 0.56
2936 || orf19.4353 || ULP2 || || SUMO deconjugation enzyme; removes the small ubiquitin-like modifier (SUMO) from proteins; Spider biofilm induced || 1 0.91 1.10 0.33 0.30 0.25 0.74 -0.19 -0.08 0.06 -0.18 0.06 0.50 -0.03 0.39 -0.07 0.70
2937 || orf19.4107 || || || Exopolyphosphatase, hydrolyzes inorganic polyphosphate (poly P) into Pi residues; Spider biofilm repressed || 1 0.82 0.80 -0.02 0.16 0.27 0.35 0.10 0.10 0.04 0.10 0.31 0.60 -0.41 0.44 -0.52 0.64
2938 || orf19.812 || || || Ortholog of C. dubliniensis CD36 : Cd36_18730, C. parapsilosis CDC317 : CPAR2_212510, Candida tenuis NRRL Y-1498 : CANTEDRAFT_135843 and Debaryomyces hansenii CBS767 : DEHA2D06732g || 1 0.29 0.83 -0.17 -0.03 0.78 -0.12 0.18 -0.10 0.37 0.46 0.56 0.50 -0.08 0.54 -0.02 0.46
2939 || orf19.3647 || SEC8 || || Predicted subunit of the exocyst complex, involved in exocytosis; localizes to a crescent on the surface of the hyphal tip || 1 0.30 0.37 -0.26 -0.09 0.27 -0.06 -0.17 -0.08 0.21 0.27 0.23 0.70 0.18 0.61 -0.05 0.53
2940 || orf19.1734 || || || Putative ATPase and nucleosome spacing factor; heterozygous null mutant displays sensitivity to virgineone || 1 0.10 0.23 -0.46 -0.02 0.18 0.22 0.18 0.11 0.14 0.35 0.30 0.48 0.27 0.60 0.33 0.38
2941 || orf19.4305 || || || Ortholog of C. dubliniensis CD36 : Cd36_52590, C. parapsilosis CDC317 : CPAR2_100565, Debaryomyces hansenii CBS767 : DEHA2G06908g and Candida guilliermondii ATCC 6260 : PGUG_02858 || 1 0.01 0.69 -0.51 0.41 -0.05 0.55 -0.16 -0.32 0.74 0.03 0.23 0.92 0.19 0.69 0.02 0.65
2942 || orf19.5387 || VPS8 || || Putative vacuolar sorting protein; downregulated upon adherence to polystyrene || 1 0.39 0.64 -0.19 0.29 0.39 0.34 -0.46 -0.13 0.82 0.28 0.17 0.54 -0.27 -0.11 0.16 0.52
2943 || orf19.4196 || || || Dubious open reading frame || 1 1.25 2.40 0.07 -0.62 -0.67 -0.21 -0.26 1.30 1.97 -0.06 1.08 0.86 0.23
2944 || orf19.3531 || || || Ortholog(s) have role in regulation of DNA-dependent DNA replication initiation and DNA replication preinitiation complex, endoplasmic reticulum, nuclear envelope, spindle pole body localization || 1 0.29 0.38 0.07 -0.17 0.14 -0.06 -0.10 0.13 0.05 0.03 0.17 0.31 0.03 -0.09 0.23 0.12
2945 || orf19.2869 || || || Ortholog of C. dubliniensis CD36 : Cd36_46110, Candida tropicalis MYA-3404 : CTRG_03792 and Candida albicans WO-1 : CAWG_03165 || 1 1.30 0.83 1.09 0.86 0.68 0.38 0.71 0.79 -1.53 0.25 0.15 0.17 1.57 0.46 0.46
2946 || orf19.5003 || || || Ortholog(s) have GTPase regulator activity and cytoplasm, nuclear envelope localization || 1 0.40 0.30 0.17 -0.12 0.53 0.27 0.51 0.28 0.21 -0.43 0.01 0.31 0.11 0.50 0.50 0.42
2947 || orf19.703 || || || Ortholog(s) have 2',3'-cyclic-nucleotide 3'-phosphodiesterase activity, role in cyclic nucleotide metabolic process and clathrin-coated vesicle localization || 1 0.34 0.26 0.17 0.07 0.38 0.11 0.25 0.55 0.28 -0.45 -0.06 0.21 0.35 0.75 0.45 0.23
2948 || orf19.7547 || || || Ortholog(s) have phosphatidylinositol-3-phosphate binding, ubiquitin-protein ligase activity, role in protein ubiquitination and cytosol, fungal-type vacuole membrane, late endosome, nucleus localization || 1 0.43 0.31 0.00 0.18 0.54 0.31 0.34 0.59 0.11 -0.29 -0.19 -0.11 0.15 0.50 0.39 0.53
2949 || orf19.430 || YPT53 || || Rab-family GTPase involved in vacuolar trafficking, colocolizes with Vps1p and Ypt52p in late endosome; Hap43-repressed gene || 1 0.42 0.24 0.37 -0.29 0.70 0.41 0.88 0.66 0.76 -0.44 -0.27 -0.49 0.93 0.63 1.12 0.32
2950 || orf19.291 || || || Ortholog(s) have role in cellular response to DNA damage stimulus, protein sumoylation, response to UV-B, response to UV-C and nuclear envelope localization || 1 0.33 0.34 -0.22 -0.04 1.15 -0.43 0.62 0.56 0.58 0.11 0.12 -0.13 0.13 0.01 0.09 0.12
2951 || orf19.5402 || || || Ortholog of Candida albicans WO-1 : CAWG_02394 || 1 -0.03 -0.02 -0.16 -0.46 0.91 0.27 0.72 0.73 0.35 -0.18 0.34 0.08 0.67 -0.06 0.32 0.11
2952 || orf19.5404 || || || Putative cell wall mannoprotein; repressed during the mating process; merged with orf19.5401 into orf19.5404.1; Spider biofilm induced || 1 0.08 -0.35 -0.24 -0.08 0.60 0.37 0.70 0.68 0.49 -0.04 0.41 0.83 0.30 0.25 0.11
2953 || orf19.1497 || ZCF6 || || Putative transcription factor with zinc cluster DNA-binding motif || 1 0.39 0.26 -0.08 -0.36 -0.07 -0.17 0.89 0.82 1.12 0.00 0.11 0.06 0.88 0.28 0.43 -0.48
2954 || orf19.2006.1 || COX17 || || Putative copper metallochaperone; Hap43p-repressed gene; rat catheter biofilm induced; Spider biofilm induced || 1 0.42 0.52 -0.40 -0.91 0.38 0.40 1.45 1.49 1.39 0.28 0.03 -0.25 0.68 0.85 0.75 -0.83
2955 || orf19.1546 || || || Membrane-localized protein of unknown function || 1 -0.03 -0.03 -0.30 -0.85 0.38 0.23 1.06 0.94 0.90 0.56 0.12 0.08 0.33 0.29 0.73 -0.10
2956 || orf19.5296 || || || Ortholog(s) have role in mitochondrial respiratory chain complex IV assembly and integral to mitochondrial inner membrane localization || 1 0.01 0.08 -0.27 -0.45 0.36 0.13 0.47 0.49 0.49 0.43 -0.02 0.17 0.14 -0.07 0.40 -0.36
2957 || orf19.4862.2 || PET100 || || Chaperone that facilitates the assembly of cytochrome c oxidase; plasma membrane protein || 1 0.93 0.91 -0.62 -0.81 1.56 1.04 1.49 1.29 0.82 -0.05 0.50 0.08 0.57 -0.06 1.28 -0.63
2958 || orf19.4862.2 || PET100 || || Chaperone that facilitates the assembly of cytochrome c oxidase; plasma membrane protein || 1 0.96 0.95 -0.10 -0.51 1.64 1.36 1.53 1.46 1.05 0.03 0.67 0.40 0.52 0.20 1.30 -0.07
2959 || orf19.2006.1 || COX17 || || Putative copper metallochaperone; Hap43p-repressed gene; rat catheter biofilm induced; Spider biofilm induced || 1 1.50 1.46 0.00 -0.58 1.01 0.53 2.28 2.37 1.69 0.15 0.41 -0.26 1.32 0.66 1.45 -0.41
2960 || orf19.5213.2 || COX9 || || Putative subunit VIIa of cytochrome c oxidase; flucytosine induced || 1 1.17 1.13 0.28 -0.01 0.64 0.40 1.18 1.09 0.48 0.01 0.37 -0.28 0.63 0.35 0.55 -0.31
2961 || orf19.5213.2 || COX9 || || Putative subunit VIIa of cytochrome c oxidase; flucytosine induced || 1 1.25 1.09 0.13 -0.37 0.73 0.26 1.38 1.40 0.38 -0.11 0.64 -0.85 0.77 0.03 0.30 -0.46
2962 || orf19.7103 || || || Predicted exonuclease; Spider biofilm induced || 1 0.12 0.05 -0.14 -0.08 0.10 0.03 0.74 0.26 0.20 -0.29 0.26 -0.28 0.13 -0.04 0.16 -0.15
2963 || orf19.7260 || || || Protein with a predicted NADP-dependent oxidoreductase or aldo-keto reductase domain; Hap43-repressed; Spider biofilm repressed || 1 0.20 0.22 -0.26 -0.10 -0.13 -0.02 1.13 0.68 0.72 0.12 0.50 -0.09 0.17 -0.01 0.17 0.02
2964 || orf19.6511 || LIG1 || || tRNA ligase; functional homolog of S. cerevisiae Trl1 || 1 0.13 0.21 -0.02 -0.17 0.16 0.21 1.04 0.33 0.94 -0.20 0.13 -0.21 0.03 -0.15 -0.06 0.23
2965 || orf19.3273 || || || Ortholog(s) have actin monomer binding, protein kinase inhibitor activity, ribosome binding activity, role in negative regulation of protein phosphorylation and cytoplasm, nucleus, polysome, ribosome localization || 1 0.44 -0.06 -0.13 -0.28 0.32 -0.04 0.44 0.18 0.35 -0.39 0.28 -0.03 0.21 0.24 0.19 0.43
2966 || orf19.7583 || ZCF39 || || Zn(II)2Cys6 transcription factor; mutants are viable; filament induced; required for yeast cell adherence to silicone substrate; Spider biofilm induced || 1 1.23 -0.12 -0.98 0.06 0.75 0.48 0.88 0.82 0.79 -0.29 1.12 0.16 0.23 0.79 0.78 0.48
2967 || orf19.2433 || || || Ortholog of C. dubliniensis CD36 : Cd36_05790, C. parapsilosis CDC317 : CPAR2_103730, Pichia stipitis Pignal : PICST_28344, Candida tropicalis MYA-3404 : CTRG_04275 and Candida albicans WO-1 : CAWG_00795 || 1 0.71 0.31 -1.06 1.53 0.36 1.53 0.51 0.17 0.29 1.32 0.37 0.13 2.37 0.52 -0.17
2968 || orf19.1535 || || || Protein of unknown function; Hap43-induced gene || 1 0.66 0.05 0.02 0.20 0.66 0.88 0.20 0.35 -0.08 -0.13 0.59 -0.15 0.23 0.01 0.27 0.08
2969 || orf19.5166 || DBF4 || || Putative Cdc7p-Dbf4p kinase complex regulatory subunit; Hap43p-induced gene; macrophage/pseudohyphal-repressed; cell-cycle regulated periodic mRNA expression; S. cerevisiae ortholog is not cell-cycle regulated || 1 0.89 0.19 -0.10 0.11 0.97 0.26 0.21 1.28 0.31 1.13 0.19 0.41 0.32 0.34 0.17 0.02
2970 || orf19.1083 || || || Putative protein of unknown function; macrophage-induced gene || 1 0.47 0.26 -0.51 -0.17 1.03 0.37 0.59 0.93 -0.18 0.63 -0.01 0.62 -0.09 0.27 0.65 0.24
2971 || orf19.5973 || PHB2 || || Prohibitin 2; plasma membrane localized || 1 0.27 0.08 -0.30 -0.32 0.75 0.22 0.53 0.64 0.30 0.24 0.22 0.22 -0.03 0.31 0.60 0.13
2972 || orf19.4775 || CTA8 || || Essential transcription factor, mediates heat shock transcriptional induction; in the absence of heat stress, Cta8p levels are modulated by growth temperature to regulate basal expression of genes involved in protein folding || 1 -0.32 -0.15 0.01 0.50 1.30 1.40 0.85 0.16 -0.35 -0.15 0.46 0.39 0.88 0.78 0.91 -0.54
2973 || orf19.4775 || CTA8 || || Essential transcription factor, mediates heat shock transcriptional induction; in the absence of heat stress, Cta8p levels are modulated by growth temperature to regulate basal expression of genes involved in protein folding || 1 -0.50 -0.44 0.09 0.41 1.21 1.27 0.56 0.22 -0.16 -0.34 0.51 0.43 0.80 0.46 0.73 -0.35
2974 || orf19.3912 || GLN3 || || GATA transcription factor, involved in regulation of nitrogen starvation-induced filamentous growth; regulates transcription of Mep2 ammonium permease; regulated by Gcn2 and Gcn4; mRNA binds She3; Spider biofilm induced || 1 -0.21 0.06 0.34 0.16 0.23 0.49 -0.02 -0.06 0.37 0.02 0.03 0.55 0.42 -0.10 0.69 -0.21
2975 || orf19.6601 || || || Protein of unknown function; rat catheter and flow model biofilm induced || 1 -0.67 -0.57 0.01 -0.52 1.45 1.36 0.60 0.26 2.02 0.66 0.02 0.54 1.31 0.19 2.11 -0.10
2976 || orf19.6601 || || || Protein of unknown function; rat catheter and flow model biofilm induced || 1 -0.67 -1.01 -0.70 -0.72 1.90 1.84 0.84 0.60 1.60 0.64 0.37 1.05 1.57 0.30 2.72 -0.04
2977 || orf19.2084 || CDH1 || || Protein involved in regulation of mitosis; similar to S. cerevisiae Cdh1, which is an APC/C component; transcriptionally induced by Mnl1 under weak acid stress || 1 0.09 0.04 0.10 -0.19 0.67 0.50 -0.14 0.24 0.18 0.03 0.31 -0.11 0.29 0.09 0.36 -0.05
2978 || orf19.445 || || || Protein of unknown function; repressed by prostaglandins || 1 0.02 0.36 0.09 0.23 0.73 0.57 0.00 0.27 0.30 0.61 0.25 0.37 0.64 0.03 0.53 -0.45
2979 || orf19.1693 || CAS4 || || RAM cell wall integrity signaling network protein; cell separation, azole sensitivity; needed for hyphal growth; insertion mutation near 3' end of gene increases caspofungin sensitivity; pheromone/hyphal induced; flow biofilm repressed || 1 -0.16 -0.12 -0.10 0.00 0.97 0.52 0.21 0.26 0.44 0.41 0.39 0.65 0.38 0.41 0.59 -0.33
2980 || orf19.1693 || CAS4 || || RAM cell wall integrity signaling network protein; cell separation, azole sensitivity; needed for hyphal growth; insertion mutation near 3' end of gene increases caspofungin sensitivity; pheromone/hyphal induced; flow biofilm repressed || 1 -0.18 0.05 0.02 -0.09 0.81 0.35 0.13 0.22 0.19 0.07 0.28 0.16 0.39 -0.03 0.37 -0.35
2981 || orf19.6373 || DCP2 || || Ortholog(s) have m7G(5')pppN diphosphatase activity, mRNA binding activity and role in deadenylation-dependent decapping of nuclear-transcribed mRNA, deadenylation-independent decapping of nuclear-transcribed mRNA, stress granule assembly || 1 0.25 0.13 0.03 0.03 0.57 0.09 0.08 0.22 0.34 -0.02 0.42 0.30 0.28 0.12 0.28 -0.32
2982 || orf19.6296 || VPS22 || || ESCRT-II complex protein with a role in multivesicular body (MVB) trafficking; required for processing of Rim8p; Hap43p-repressed gene || 1 0.18 0.11 -0.18 -0.29 0.27 0.28 0.41 0.14 0.44 -0.54 0.50 0.51 0.42 0.83 0.09 0.41
2983 || orf19.6296 || VPS22 || || ESCRT-II complex protein with a role in multivesicular body (MVB) trafficking; required for processing of Rim8p; Hap43p-repressed gene || 1 0.05 0.31 -0.07 -0.58 0.23 0.37 0.23 -0.05 0.33 -0.57 0.48 0.83 0.42 0.98 0.67 0.30
2984 || orf19.6296 || VPS22 || || ESCRT-II complex protein with a role in multivesicular body (MVB) trafficking; required for processing of Rim8p; Hap43p-repressed gene || 1 -0.04 0.09 -0.74 -0.38 0.09 0.25 -0.01 0.06 0.24 -0.53 0.50 0.81 0.18 0.87 0.64 0.65
2985 || orf19.6017 || || || Protein of unknown function; Spider biofilm induced || 1 -0.04 0.28 -0.18 -0.96 0.73 -0.15 0.54 -0.00 -0.11 -0.97 1.00 1.65 0.77 0.63 1.06 0.55
2986 || orf19.1324 || RAD2 || || Ortholog of S. cerevisiae Rad2, a nucleotide excision repair nuclease; null mutant is extremely sensitive to UV irradiation; transcript induced by interaction with macrophages || 1 0.40 0.11 -0.07 -0.19 0.32 0.10 0.12 -0.07 0.16 0.09 0.15 0.44 -0.01 0.08 0.80 0.22
2987 || orf19.6031 || VPS27 || || Putative ESCRT-0 complex protein with a role in multivesicular body (MVB) trafficking || 1 0.19 0.28 0.20 0.10 0.66 0.49 0.21 0.04 0.15 0.03 0.41 0.69 0.11 0.61 1.02 1.04
2988 || orf19.5752 || || || Ortholog(s) have ubiquitin-protein ligase activity, role in SCF-dependent proteasomal ubiquitin-dependent protein catabolic process and SCF ubiquitin ligase complex localization || 1 0.21 0.17 0.11 0.01 0.37 0.20 0.13 -0.20 0.24 -0.12 0.12 0.41 -0.20 0.66 0.96 0.74
2989 || orf19.5752 || || || Ortholog(s) have ubiquitin-protein ligase activity, role in SCF-dependent proteasomal ubiquitin-dependent protein catabolic process and SCF ubiquitin ligase complex localization || 1 0.19 0.33 0.15 0.15 0.44 0.29 0.10 0.09 0.32 0.02 0.27 0.26 -0.19 0.76 1.05 0.57
2990 || orf19.5935 || || || Ortholog of C. dubliniensis CD36 : Cd36_84710, C. parapsilosis CDC317 : CPAR2_807470, Candida tenuis NRRL Y-1498 : CANTEDRAFT_136475 and Debaryomyces hansenii CBS767 : DEHA2B08844g || 1 0.29 0.35 0.01 0.13 0.40 -0.07 0.31 -0.16 0.18 -0.10 0.09 0.04 0.19 0.28 0.62 0.39
2991 || orf19.1927 || SNM1 || || Protein similar to RNase MRP RNA binding protein; ciclopirox olamine induced; regulated by Sef1, Sfu1, and Hap43; Spider biofilm induced || 1 0.20 0.47 -0.22 -0.08 1.13 0.90 0.71 0.39 0.06 0.38 -0.25 0.15 0.54 0.39 1.22 0.41
2992 || orf19.4929 || || || Ortholog(s) have translation regulator activity and role in RNA metabolic process, aerobic respiration, mitochondrial respiratory chain complex IV biogenesis, positive regulation of mitochondrial translational initiation || 1 0.14 0.18 -0.30 -0.89 0.79 0.97 0.60 0.63 0.54 0.26 0.03 0.49 0.74 0.19 0.83 0.43
2993 || orf19.4929 || || || Ortholog(s) have translation regulator activity and role in RNA metabolic process, aerobic respiration, mitochondrial respiratory chain complex IV biogenesis, positive regulation of mitochondrial translational initiation || 1 0.23 0.23 -0.37 -1.00 0.86 0.67 0.99 0.59 0.60 0.31 0.20 0.20 0.91 0.46 0.94 0.14
2994 || orf19.1107 || || || Protein of unknown function; Spider biofilm induced || 1 0.37 0.20 -0.88 -0.62 0.78 -0.11 0.41 0.23 0.09 -0.60 0.58 0.24 0.45 -0.07 1.21 0.34
2995 || orf19.4882 || || || TFIIE small subunit; involved in RNA polymerase II transcription initiation; Spider biofilm induced || 1 0.51 -0.09 -1.17 -0.42 0.66 0.18 0.54 0.28 0.32 -0.17 0.66 0.43 0.26 0.17 0.61 0.27
2996 || orf19.2647 || ZCF14 || || Putative Zn(II)2Cys6 transcription factor; caspofungin induced || 1 0.89 0.18 -1.14 -1.33 0.56 0.32 0.61 0.35 0.27 0.20 0.76 1.06 -0.04 0.72 0.90 0.89
2997 || orf19.794 || SSN3 || || Putative cyclin-dependent protein kinase; mutants are sensitive to growth on H2O2 medium || 1 0.53 0.76 -0.63 -0.94 0.60 0.17 0.58 0.37 0.14 -0.08 0.75 0.32 0.07 0.19 0.64 0.52
2998 || orf19.4275 || RAD9 || || DNA damage-dependent checkpoint protein; involved in regulation of DNA-damage-induced filamentous growth; induced by alpha pheromone in SpiderM medium || 1 0.34 0.43 -0.11 -0.62 1.09 -0.09 -0.02 0.47 0.36 0.19 0.39 0.26 0.60 0.37 0.79 0.30
2999 || orf19.1552 || CPR3 || || Putative peptidyl-prolyl cis-trans isomerase; macrophage-induced protein; protein levels decrease in stationary phase yeast cultures; predicted mitochondrial localization; overlaps orf19.1551 || 1 0.14 0.13 -0.38 -0.40 0.56 0.04 0.18 0.19 0.40 -0.03 0.28 0.29 0.30 0.40 0.36 0.21
3000 || orf19.1590 || || || Ortholog of C. dubliniensis CD36 : Cd36_18970, C. parapsilosis CDC317 : CPAR2_212800, Debaryomyces hansenii CBS767 : DEHA2F08690g and Candida guilliermondii ATCC 6260 : PGUG_01488 || 1 0.11 0.15 -0.31 -1.18 1.06 -0.26 0.90 0.19 0.56 -0.00 0.61 1.19 0.26 0.22 1.40 0.38
3001 || orf19.2367 || || || Putative protein of unknown function; Hap43-induced; repressed by Rim101; Spider biofilm induced || 1 -0.14 0.40 -0.28 -0.76 0.93 0.33 0.33 0.35 0.61 0.44 0.92 1.17 0.43 -0.12 0.69 0.21
3002 || orf19.454 || SFL1 || || Transcription factor involved in negative regulation of morphogenesis, flocculation and virulence; induced in core caspofungin response; Spider biofilm induced || 1 -0.09 0.01 -0.18 -0.29 0.50 0.55 0.68 0.01 0.01 0.05 1.70 1.43 1.07 -0.08 0.83 0.42
3003 || orf19.7173 || || || Ortholog of C. parapsilosis CDC317 : CPAR2_702310, C. dubliniensis CD36 : Cd36_73730, Lodderomyces elongisporus NRLL YB-4239 : LELG_04029 and Candida orthopsilosis Co 90-125 : CORT_0G02490 || 1 0.37 0.06 0.24 -0.26 0.35 0.55 0.07 0.12 0.09 0.30 1.11 1.04 0.92 0.02 0.49 0.32
3004 || orf19.6636 || || || Protein of unknown function; rat catheter biofilm repressed || 1 -0.01 0.09 0.06 -0.24 0.44 0.42 0.00 0.18 -0.21 0.00 0.78 0.72 0.63 0.12 0.25 0.31
3005 || orf19.4250 || || || Ortholog of C. dubliniensis CD36 : Cd36_52200, C. parapsilosis CDC317 : CPAR2_502480, Candida tenuis NRRL Y-1498 : CANTEDRAFT_115972 and Debaryomyces hansenii CBS767 : DEHA2G19976g || 1 -0.05 0.16 -0.09 -0.20 0.91 0.91 0.17 0.49 -0.17 0.50 1.21 0.95 0.45 -0.30 0.59 0.72
3006 || orf19.2542 || || || Ortholog(s) have nucleus localization || 1 1.09 0.45 -0.19 0.28 1.12 1.56 0.66 0.59 0.83 0.30 0.66 0.25 0.52 0.33 0.84 0.82
3007 || orf19.6465 || || || Ortholog of C. dubliniensis CD36 : Cd36_83910, Candida tropicalis MYA-3404 : CTRG_05087 and Candida albicans WO-1 : CAWG_00654 || 1 0.34 0.40 0.37 0.12 1.03 0.82 0.47 0.51 0.45 -0.01 0.44 0.16 0.13 -0.38 0.48 0.57
3008 || orf19.6739 || || || Ortholog(s) have phosphopentomutase activity, role in deoxyribose phosphate catabolic process and cytosol, nucleus localization || 1 0.73 0.52 0.32 0.01 0.77 0.83 0.38 0.39 0.42 -0.38 0.32 0.56 -0.08 -0.04 0.56 0.71
3009 || orf19.2419 || || || Ortholog of S. cerevisiae Dom34; a protein that facilitates ribosomal subunit dissociation when translation is stalled; peloto ortholog; Hap43-repressed gene || 1 0.37 0.31 0.54 0.35 0.46 1.08 0.54 0.38 0.58 0.17 0.41 0.68 -0.13 -0.24 0.49 0.55
3010 || orf19.1712 || GEA2 || || Putative ARF GTP/GDP exchange factor; induced in low iron; flow model biofilm repressed || 1 0.38 0.17 0.21 -0.02 0.49 0.22 -0.02 0.13 -0.10 0.09 0.46 0.77 0.09 -0.03 0.61 0.44
3011 || orf19.3647 || SEC8 || || Predicted subunit of the exocyst complex, involved in exocytosis; localizes to a crescent on the surface of the hyphal tip || 1 0.30 0.26 -0.10 0.01 0.65 0.11 -0.01 0.05 0.01 0.05 0.75 0.65 0.09 0.36 0.32 0.73
3012 || orf19.2822 || || || Essential component of the conserved oligomeric Golgi complex; role in fusion of transport vesicles to Golgi compartments; rat catheter biofilm repressed || 1 0.58 0.08 -0.05 -0.21 0.23 0.00 0.07 0.34 0.13 -0.26 0.89 0.73 0.08 0.23 0.43 0.77
3013 || orf19.7206 || OCA6 || || Putative protein phosphatase of the PTP family (tyrosine-specific), similar to S. cerevisiae Oca6p; mutant shows virulence defect || 1 0.14 0.15 0.25 0.09 0.07 -0.15 0.06 0.25 0.07 -0.03 0.24 0.34 0.01 0.20 0.41 0.32
3014 || orf19.7178 || PRE5 || || Alpha6 subunit of the 20S proteasome; regulated by Gcn4; induced in response to amino acid starvation (3-AT); Spider biofilm repressed || 1 0.24 0.27 0.09 0.26 -0.06 -0.08 0.07 0.35 0.11 0.16 0.40 0.60 -0.04 0.36 0.61 0.36
3015 || orf19.6063 || UBP6 || || Putative ubiquitin-specific protease of the 26S proteasome; oxidative stress-induced via Cap1p || 1 0.48 0.40 0.11 0.12 0.39 -0.06 0.32 0.44 0.09 0.46 0.56 0.66 -0.06 0.37 0.81 0.61
3016 || orf19.6626 || || || Predicted homeodomain-containing protein; possible transcription factor; possibly transcriptionally regulated upon hyphal formation || 1 0.39 0.46 0.33 -0.01 0.41 0.23 0.27 0.67 0.38 0.21 0.46 0.90 -0.14 0.15 0.94 0.91
3017 || orf19.5618 || || || Ortholog(s) have SNARE binding, unfolded protein binding activity || 1 0.31 0.34 -0.06 -0.06 0.38 0.06 0.19 0.17 -0.04 0.09 0.81 0.81 -0.09 0.57 1.00 0.80
3018 || orf19.2301 || || || Ortholog(s) have role in proteasome regulatory particle assembly and cytosol, nucleus localization || 1 0.30 0.36 -0.07 0.15 0.35 -0.13 0.14 0.29 0.35 0.28 0.71 0.61 0.23 0.26 0.73 0.34
3019 || orf19.933 || || || Ortholog(s) have protein homodimerization activity, ubiquitin-protein ligase activity and role in UV-damage excision repair, free ubiquitin chain polymerization, postreplication repair, protein K63-linked ubiquitination || 1 0.45 0.22 0.05 -0.11 0.33 0.22 0.24 0.47 0.20 0.04 0.51 0.61 0.21 0.58 0.82 0.30
3020 || orf19.6804 || || || Ortholog(s) have signal sequence binding activity, role in protein targeting to ER and cytosol, nuclear periphery, signal recognition particle, endoplasmic reticulum targeting localization || 1 0.31 0.14 -0.40 0.08 0.34 -0.06 0.54 0.59 0.20 0.62 0.69 1.07 0.17 0.27 0.82 0.78
3021 || orf19.4767 || ZCF28 || || Zn(II)2Cys6 transcription factor; required for yeast cell adherence to silicone substrate; Spider biofilm induced || 1 0.43 0.54 0.14 -0.02 0.59 0.33 0.25 0.39 0.43 0.06 0.62 0.69 0.42 0.32 0.56 0.54
3022 || orf19.1107 || || || Protein of unknown function; Spider biofilm induced || 1 0.57 0.56 0.07 0.32 0.83 0.40 0.45 0.31 0.62 -0.18 0.74 0.89 0.64 0.34 1.03 1.13
3023 || orf19.1107 || || || Protein of unknown function; Spider biofilm induced || 1 0.68 0.65 -0.35 0.06 0.61 -0.03 0.78 0.56 0.65 0.11 0.78 0.61 0.61 0.13 1.05 1.01
3024 || orf19.4253 || || || Ortholog(s) have role in negative regulation of gluconeogenesis, proteasome-mediated ubiquitin-dependent protein catabolic process, regulation of nitrogen utilization, vacuolar protein catabolic process || 1 0.37 0.23 0.01 -0.23 0.29 0.06 0.45 0.24 0.48 -0.32 0.41 0.54 0.25 0.20 0.68 0.65
3025 || orf19.2921 || || || Ortholog(s) have alpha-tubulin binding activity, role in protein folding, tubulin complex assembly and cytosol, nucleus localization || 1 0.06 0.47 0.14 -0.05 0.56 0.17 0.38 0.18 0.42 0.06 0.11 0.69 0.31 0.06 0.79 0.78
3026 || orf19.1610 || || || Putative protein of unknown function, transcription is activated in the presence of elevated CO2 || 1 0.13 0.39 -0.10 -0.21 0.66 0.81 0.11 0.90 0.16 -0.16 0.42 1.13 0.20 0.50 0.79 0.87
3027 || orf19.5825 || NCB2 || || Beta subunit of NC2, heterodimeric regulator of transcription; activates CDR1 transcription; possibly an essential gene, disruptants not obtained by UAU1 method; conditional mutants show decreased susceptibility to azoles || 1 -0.02 0.21 0.07 0.12 0.48 0.81 -0.20 0.25 -0.01 0.46 0.43 0.61 0.16 0.67 0.43 0.43
3028 || orf19.3023 || NGG1 || || Ortholog(s) have histone acetyltransferase activity and role in cellular response to cadmium ion, detoxification of cadmium ion, histone acetylation, regulation of transcription from RNA polymerase II promoter || 1 0.01 0.19 -0.03 0.02 0.57 0.67 -0.13 0.08 0.15 0.48 0.63 1.05 0.38 0.57 0.74 0.28
3029 || orf19.5465 || || || Ortholog(s) have first spliceosomal transesterification activity, role in generation of catalytic spliceosome for first transesterification step and U2-type catalytic step 1 spliceosome, mitotic spindle pole body localization || 1 -0.13 0.26 0.20 0.37 0.45 0.68 0.35 0.13 0.13 0.39 0.24 0.79 0.63 0.53 1.09 0.36
3030 || orf19.2379 || NOT4 || || Putative E3 ubiquitin-protein ligase; required for maintenance, but not induction, of hyphal development; homozygous null mutant is avirulent in mouse systemic infection despite persistence in host; repressed in rat oral candidiasis || 1 0.31 0.23 0.25 0.41 0.41 0.58 0.17 0.05 0.04 0.38 0.33 0.46 0.44 0.24 0.65 0.27
3031 || orf19.991 || DJP1 || || Similar to bacterial DnaJ; reported to have a role in peroxisome biogenesis; induced in low iron and upon adherence to polystyrene || 1 0.31 0.35 0.04 0.08 0.42 0.47 0.28 0.47 -0.20 0.56 0.50 0.53 0.15 0.46 0.76 0.39
3032 || orf19.5277 || || || Ortholog(s) have role in nuclear-transcribed mRNA catabolic process, 3'-5' exonucleolytic nonsense-mediated decay, protein ubiquitination and cytoplasm, nucleolus, polysome localization || 1 0.84 0.79 0.29 1.09 0.65 1.37 1.20 0.62 -0.51 1.04 2.01 1.35 0.55 0.69 1.44 0.64
3033 || orf19.3748 || || || Protein of unknown function; orf19.3747 and orf19.3748 are short, overlapping ORFs in intergenic region between 2 oligopeptide transporter-encoding genes; flow model biofilm induced || 1 0.93 0.86 0.73 -0.16 0.60 1.35 0.43 0.12 -0.58 0.55 1.10 0.91 0.10 0.47 0.94 -0.00
3034 || orf19.2721 || || || Ortholog(s) have role in ascospore formation, regulation of mitotic cell cycle, regulation of translation and cytosol, nucleus localization || 1 0.26 0.38 0.26 0.17 0.35 0.75 0.11 0.22 -0.21 0.26 0.38 0.58 -0.05 0.25 0.20 0.19
3035 || orf19.5051 || || || Has domain(s) with predicted protein heterodimerization activity || 1 0.27 0.32 0.51 0.30 0.82 1.38 0.05 0.14 -0.77 0.22 0.66 1.03 0.36 0.60 0.68 0.35
3036 || orf19.4582 || || || Ortholog(s) have role in U1 snRNA 3'-end processing, U4 snRNA 3'-end processing and U5 snRNA 3'-end processing, more || 1 0.11 0.06 0.26 -0.09 0.54 0.91 0.31 0.15 -0.21 0.27 0.31 0.26 0.01 0.41 0.25 0.35
3037 || orf19.1975 || || || Ortholog(s) have role in mRNA splicing, via spliceosome, regulation of DNA methylation and U4/U6 x U5 tri-snRNP complex, U5 snRNP localization || 1 0.41 0.19 0.50 0.00 0.68 1.16 0.41 0.56 -0.03 -0.06 0.36 0.42 -0.02 0.36 0.79 0.55
3038 || orf19.3178 || || || Ortholog(s) have RNA binding activity, role in mRNA splicing, via spliceosome and U2-type prespliceosome localization || 1 0.31 0.51 -0.28 0.03 0.60 0.77 0.35 0.02 0.13 -0.03 0.33 0.29 0.47 0.08 0.55 0.47
3039 || orf19.3515 || || || Putative 3-hydroxyanthranilic acid dioxygenase, involved in NAD biosynthesis; Hap43p-repressed gene || 1 0.84 0.88 0.15 -0.46 1.34 1.28 0.52 0.70 0.24 -0.61 0.64 0.49 0.43 0.35 0.80 0.95
3040 || orf19.50 || || || Ortholog(s) have role in SCF-dependent proteasomal ubiquitin-dependent protein catabolic process, cellular response to DNA damage stimulus, cellular response to methylmercury and SCF ubiquitin ligase complex, cytosol, nucleus localization || 1 1.42 1.56 -0.13 -0.46 2.29 2.07 0.67 0.35 0.37 -0.47 0.97 0.27 0.44 0.38 0.75 1.29
3041 || orf19.3007 || || || Ortholog(s) have role in endosome organization, regulation of protein localization and BLOC-1 complex localization || 1 1.02 1.08 0.09 -0.03 1.69 1.38 0.66 0.11 -0.16 -0.34 0.96 0.20 0.25 0.20 0.92 1.06
3042 || orf19.7227 || || || Protein phosphatase inhibitor; Hap43-repressed; homozygous Tn insertion decreases colony wrinkling but does not block hyphal growth in liquid media; mutation confers hypersensitivity to toxic ergosterol analog; Spider biofilm induced || 1 1.00 1.37 0.76 0.23 2.82 3.03 0.56 0.58 -0.25 -0.76 1.49 0.21 0.23 0.14 1.56 1.80
3043 || orf19.6349 || RVS162 || || Protein containing a BAR domain, which is found in proteins involved in membrane curvature; null mutant does not display the endocytic, hyphal growth, virulence, or cell wall defects exhibited by mutants in related genes RVS161 and RVS167 || 1 0.55 0.44 0.11 -0.09 2.03 1.69 0.56 0.11 0.04 -0.79 1.02 0.27 0.70 -0.40 1.46 1.32
3044 || orf19.6349 || RVS162 || || Protein containing a BAR domain, which is found in proteins involved in membrane curvature; null mutant does not display the endocytic, hyphal growth, virulence, or cell wall defects exhibited by mutants in related genes RVS161 and RVS167 || 1 0.62 0.71 0.13 -0.07 1.99 1.65 0.42 0.36 -0.11 -0.76 1.25 0.74 0.90 -0.33 1.60 1.38
3045 || orf19.5225 || || || Ortholog of Candida albicans WO-1 : CAWG_00201 || 1 0.28 0.38 -0.09 -0.24 0.83 0.89 0.47 0.02 0.03 -0.50 0.93 0.56 0.39 -0.17 0.98 0.62
3046 || orf19.5225 || || || Ortholog of Candida albicans WO-1 : CAWG_00201 || 1 0.35 0.47 0.04 -0.07 1.05 0.90 0.69 0.35 -0.31 -0.54 1.15 0.90 0.24 -0.17 1.18 0.87
3047 || orf19.7598 || || || Ortholog(s) have histone acetyltransferase activity, role in histone acetylation and Ada2/Gcn5/Ada3 transcription activator complex localization || 1 0.53 0.57 0.37 0.29 1.04 0.82 0.04 -0.08 0.11 -0.21 0.64 0.34 0.35 -0.10 1.08 0.63
3048 || orf19.3999 || || || Ortholog(s) have fungal-type vacuole membrane localization || 1 0.60 0.98 0.20 0.38 1.25 0.81 -0.08 -0.02 0.16 -0.11 0.84 0.72 0.48 -0.31 0.82 0.55
3049 || orf19.7598 || || || Ortholog(s) have histone acetyltransferase activity, role in histone acetylation and Ada2/Gcn5/Ada3 transcription activator complex localization || 1 0.88 0.68 0.34 -0.02 1.16 0.85 -0.06 -0.13 -0.07 0.23 0.95 0.59 0.01 0.03 1.17 0.93
3050 || orf19.7598 || || || Ortholog(s) have histone acetyltransferase activity, role in histone acetylation and Ada2/Gcn5/Ada3 transcription activator complex localization || 1 0.57 0.52 0.20 -0.12 1.04 0.92 0.07 0.05 0.02 0.13 1.07 0.96 -0.29 0.33 1.38 1.00
3051 || orf19.7598 || || || Ortholog(s) have histone acetyltransferase activity, role in histone acetylation and Ada2/Gcn5/Ada3 transcription activator complex localization || 1 0.42 0.51 0.03 -0.06 0.91 0.93 -0.09 -0.17 -0.05 0.07 0.70 0.66 -0.49 0.00 1.01 0.87
3052 || orf19.6979 || || || Ortholog(s) have role in cellular manganese ion homeostasis, mitochondrion organization and fungal-type vacuole membrane localization || 1 0.22 0.23 0.17 0.12 0.96 0.93 -0.43 -0.42 -0.34 -0.50 0.93 0.83 0.19 -0.27 1.17 0.90
3053 || orf19.2089 || || || Ortholog of Nyv1, v-SNARE component of the vacuolar SNARE complex involved in vesicle fusion in S. cerevisiae; Hap43-repressed gene || 1 0.05 0.16 0.15 -0.06 0.36 0.56 -0.07 -0.19 0.05 -0.22 0.34 0.25 -0.09 -0.02 0.35 0.42
3054 || orf19.3726 || || || Ortholog of C. dubliniensis CD36 : Cd36_65640 and Candida albicans WO-1 : CAWG_01583 || 1 0.17 0.28 0.09 -0.03 0.90 0.87 -0.17 -0.04 0.12 -0.28 0.28 0.67 -0.14 -0.25 0.70 0.74
3055 || orf19.335 || || || Sef1p-, Sfu1p-, and Hap43p-regulated gene || 1 0.44 0.38 -0.07 -0.08 1.21 0.77 -0.32 0.13 0.30 -0.76 0.68 0.61 -0.13 0.06 1.14 0.73
3056 || orf19.4764 || || || Ortholog(s) have poly(A)-specific ribonuclease activity, role in mRNA 3'-end processing, postreplication repair and PAN complex localization || 1 0.22 0.09 -0.04 -0.11 0.86 0.72 -0.12 0.07 0.07 -0.40 0.42 0.45 0.26 0.28 0.53 0.46
3057 || orf19.810 || || || Ortholog(s) have DNA helicase activity, role in DNA unwinding involved in DNA replication, reciprocal meiotic recombination, synapsis and nucleus localization || 1 0.54 0.36 -0.11 -0.09 1.70 1.34 0.38 -0.10 -0.22 -0.72 0.54 0.81 0.04 0.79 1.92 1.03
3058 || orf19.1670 || BRO1 || || Class E vacuolar protein sorting factor; role in transport from multivesicular body to vacuole; not involved in Rim101 pathway; macrophage and pseudohyphal-repressed; flow model biofilm induced || 1 0.63 0.41 -0.18 0.04 0.95 0.55 0.38 -0.09 -0.06 -0.33 0.16 0.49 0.32 0.10 1.12 0.43
3059 || orf19.7344 || || || Ortholog(s) have DNA binding, chromatin binding, histone deacetylase activity || 1 0.29 0.22 -0.05 0.21 1.41 1.26 0.05 -0.31 -0.61 -0.81 0.55 0.85 0.66 -0.48 1.86 0.46
3060 || orf19.7344 || || || Ortholog(s) have DNA binding, chromatin binding, histone deacetylase activity || 1 0.55 0.48 -0.10 -0.10 1.73 1.31 0.16 0.05 -0.50 -0.44 0.65 0.60 0.70 -0.68 1.96 0.58
3061 || orf19.1681 || || || Ortholog of C. dubliniensis CD36 : Cd36_81530, C. parapsilosis CDC317 : CPAR2_503590, Candida tenuis NRRL Y-1498 : CANTEDRAFT_115755 and Debaryomyces hansenii CBS767 : DEHA2D15334g || 1 0.43 0.54 -0.06 0.02 1.73 1.41 -0.16 0.13 -0.93 -0.61 1.12 0.47 0.05 -0.65 1.89 0.12
3062 || orf19.1681 || || || Ortholog of C. dubliniensis CD36 : Cd36_81530, C. parapsilosis CDC317 : CPAR2_503590, Candida tenuis NRRL Y-1498 : CANTEDRAFT_115755 and Debaryomyces hansenii CBS767 : DEHA2D15334g || 1 0.41 0.40 0.18 0.14 1.36 1.44 -0.06 0.22 -0.33 -0.35 0.90 0.75 0.08 -0.27 1.58 0.35
3063 || orf19.6517 || RAD14 || || Putative DNA repair protein; transcription is regulated upon yeast-hyphal switch; flucytosine repressed || 1 0.08 0.10 0.28 0.17 0.64 1.15 0.32 0.02 0.17 -0.17 0.29 0.78 -0.04 -0.18 0.97 0.81
3064 || orf19.4610 || || || Predicted metallocarboxypeptidase; role in proteolysis; rat catheter biofilm repressed || 1 0.16 -0.02 0.22 0.17 1.01 0.93 0.29 -0.02 0.42 -0.12 0.00 0.35 0.21 -0.34 1.03 0.70
3065 || orf19.7235 || || || Putative protein of unknown function; mutation confers hypersensitivity to amphotericin B || 1 -0.23 -0.20 0.14 -0.03 0.86 0.97 -0.03 -0.02 -0.03 -0.55 0.06 0.44 0.23 -0.13 0.83 0.71
3066 || orf19.3298 || CCH1 || || Voltage-gated Ca2+ channel of the high affinity calcium uptake system; roles in thigmotropism, establishment of galvanotropism; transcript regulated by Nrg1 and Mig1; flow model biofilm repressed || 1 0.06 0.19 0.08 -0.19 0.73 0.69 0.42 -0.04 0.03 -0.34 0.07 0.53 0.36 0.11 0.56 0.78
3067 || orf19.4752 || MSN4 || || Zinc finger transcription factor; similar to S. cerevisiae Msn4, but not a significant stress response regulator in C. albicans; partly complements STRE-activation defect of S. cerevisiae msn2 msn4 double mutant; flow model biofilm induced || 1 0.20 0.15 -0.17 -0.28 1.06 1.54 -0.18 -0.45 0.26 -0.86 0.12 0.54 0.72 -0.19 1.34 0.76
3068 || orf19.4752 || MSN4 || || Zinc finger transcription factor; similar to S. cerevisiae Msn4, but not a significant stress response regulator in C. albicans; partly complements STRE-activation defect of S. cerevisiae msn2 msn4 double mutant; flow model biofilm induced || 1 0.41 0.37 -0.28 -0.50 1.56 1.53 -0.01 -0.33 -0.15 -1.10 0.17 0.21 1.05 -0.49 1.39 0.68
3069 || orf19.4752 || MSN4 || || Zinc finger transcription factor; similar to S. cerevisiae Msn4, but not a significant stress response regulator in C. albicans; partly complements STRE-activation defect of S. cerevisiae msn2 msn4 double mutant; flow model biofilm induced || 1 0.44 0.33 -0.19 -0.54 1.71 1.34 0.27 -0.18 -0.45 -1.07 0.51 0.00 1.09 -0.11 1.42 0.64
3070 || orf19.173 || || || C2H2 transcription factor; induced by Mnl1 under weak acid stress || 1 0.03 0.01 -0.28 -0.82 1.01 0.59 -0.08 -0.08 -0.13 -0.49 0.41 0.01 0.76 0.19 0.78 0.50
3071 || orf19.7344 || || || Ortholog(s) have DNA binding, chromatin binding, histone deacetylase activity || 1 -0.29 0.08 -0.72 -0.82 1.66 1.52 0.06 -0.34 -0.28 -0.29 0.73 0.47 0.78 0.23 1.93 0.74
3072 || orf19.1203 || SRO77 || || Protein with a predicted role in docking and fusion of post-Golgi vesicles with the plasma membrane; filament induced; fungal-specific (no human or murine homolog) || 1 0.13 0.10 0.06 -0.19 0.50 0.45 0.10 0.12 0.05 -0.03 0.25 -0.05 0.14 0.34 0.47 0.39
3073 || orf19.5450 || ETR1 || || Putative 2-enoyl thioester reductase; protein present in exponential and stationary growth phase yeast cultures; rat catheter biofilm repressed || 1 -0.07 0.00 0.23 -0.07 0.42 0.57 0.06 0.07 0.10 -0.02 0.18 0.32 0.20 0.03 0.38 0.08
3074 || orf19.328 || NPR2 || || Putative urea transporter; induced during infection of murine kidney, compared to growth in vitro; has murine homolog || 1 0.23 0.00 0.03 0.06 0.74 0.88 0.12 0.14 0.32 0.18 0.28 0.53 0.21 0.25 0.54 -0.07
3075 || orf19.7016 || PHM5 || || Ortholog(s) have endopolyphosphatase activity, exopolyphosphatase activity, role in polyphosphate catabolic process and fungal-type vacuole membrane, nucleus localization || 1 0.14 0.31 -0.14 -0.06 1.70 1.91 0.29 0.53 0.24 0.23 1.01 0.55 0.20 0.53 0.78 0.06
3076 || orf19.3742 || || || Protein of unknown function; Spider biofilm induced; upregulated in a cyr1 null mutant || 1 -0.09 0.15 -0.01 -0.35 1.61 1.61 0.31 -0.03 0.06 -0.27 0.86 0.52 0.26 0.56 1.01 0.30
3077 || orf19.144 || SNU114 || || Protein similar to S. cerevisiae Snu114p, which is an RNA helicase involved in pre-mRNA splicing; likely to be essential for growth, based on an insertional mutagenesis strategy || 1 0.54 0.47 -0.48 -0.74 1.18 0.64 0.30 -0.13 -0.43 0.26 0.41 0.59 0.70 0.29 0.88 0.25
3078 || orf19.4629 || || || Ortholog(s) have ubiquitin-ubiquitin ligase activity, role in mitochondrion inheritance, protein monoubiquitination, protein polyubiquitination and plasma membrane, ubiquitin ligase complex localization || 1 0.53 0.55 -0.19 -0.21 1.41 0.85 0.33 -0.14 0.28 0.05 0.43 0.64 1.12 0.43 0.78 0.06
3079 || orf19.4275 || RAD9 || || DNA damage-dependent checkpoint protein; involved in regulation of DNA-damage-induced filamentous growth; induced by alpha pheromone in SpiderM medium || 1 0.47 0.40 -0.21 -0.56 1.24 0.33 0.24 0.43 0.04 -0.17 0.57 0.36 0.77 0.51 0.80 0.03
3080 || orf19.3256 || SLN1 || || Histidine kinase involved in a two-component signaling pathway that regulates cell wall biosynthesis; mutants are sensitive to growth on H2O2 medium; rat catheter and Spider biofilm induced || 1 0.67 0.56 -0.45 -0.44 0.93 0.32 0.92 0.46 0.03 -0.19 0.59 0.46 0.99 0.53 0.79 0.14
3081 || orf19.3479 || || || Predicted ORF in Assemblies 19, 20 and 21; merged with orf19.3477 || 1 0.78 1.03 -1.04 -0.28 1.16 1.14 1.66 0.79 -0.58 0.80 1.59 -0.12 1.32 0.65 1.25 0.51
3082 || orf19.2820 || || || Ortholog(s) have nucleocytoplasmic transporter activity, structural constituent of nuclear pore activity || 1 0.40 0.45 -0.31 -0.34 0.51 0.25 0.55 0.46 -0.09 0.21 0.63 0.23 0.35 0.35 0.48 -0.06
3083 || orf19.2831 || RPC31 || || Putative RNA polymerase III subunit C31; repressed by nitric oxide; induced during infection of murine kidney, compared to growth in vitro; has murine homolog || 1 1.05 1.33 -0.14 -0.62 1.86 0.86 1.26 1.02 -0.39 0.84 0.96 0.15 0.54 0.56 0.99 -0.20
3084 || orf19.6455 || || || Protein of unknown function, transcript is upregulated in clinical isolates from HIV+ patients with oral candidiasis || 1 0.54 0.69 -0.18 -0.23 0.96 0.40 0.56 0.31 -0.69 -0.03 0.79 -0.11 0.22 -0.17 0.76 -0.10
3085 || orf19.6195 || || || Ortholog(s) have 3'-5'-exoribonuclease activity || 1 0.64 0.64 -0.53 -0.60 1.33 0.61 0.56 0.62 -0.32 0.19 1.13 0.35 0.73 -0.54 1.06 0.47
3086 || orf19.4987 || NUP49 || || Nuclear pore protein || 1 0.78 0.81 -0.04 -0.23 1.17 0.68 0.50 0.33 -0.43 0.14 0.75 0.39 0.79 -0.24 1.08 0.54
3087 || orf19.2901 || NUP60 || || Ortholog of S. cerevisiae Nup60p; a subunit of the nuclear pore complex; mutants are viable || 1 0.44 0.38 -0.19 -0.16 1.02 0.84 0.39 0.16 -0.34 0.13 0.59 0.41 0.50 -0.29 1.04 0.22
3088 || orf19.515 || || || Has domain(s) with predicted nucleic acid binding, zinc ion binding activity || 1 0.19 0.54 0.04 -0.44 1.68 1.26 0.88 0.44 -0.49 0.08 0.80 -0.16 0.76 0.01 1.32 -0.07
3089 || orf19.7443 || || || Ortholog of C. dubliniensis CD36 : Cd36_86510, C. parapsilosis CDC317 : CPAR2_206110, Candida tenuis NRRL Y-1498 : CANTEDRAFT_112184 and Debaryomyces hansenii CBS767 : DEHA2F17292g || 1 0.42 0.24 -0.26 -0.67 1.16 1.15 0.51 0.93 -0.65 0.34 1.04 0.49 0.17 0.46 1.36 0.08
3090 || orf19.738 || MYO5 || || Class I myosin; nonessential; role in cortical actin patch polarity and polar budding; required for hyphal growth, white-opaque switch; regulatory phosphorylation on S366; downregulated on adherence to polystyrene || 1 0.11 0.03 -0.20 -0.26 0.77 0.25 0.66 0.35 0.21 -0.18 0.54 0.34 0.51 0.48 0.95 0.86
3091 || orf19.6118 || || || Putative guanine nucleotide dissociation stimulator; transcription is positively regulated by Tbf1p || 1 0.20 0.13 -0.64 -0.25 1.84 1.16 0.38 1.26 -0.32 -0.05 1.29 0.80 0.51 0.22 1.10 1.11
3092 || orf19.1028 || ELA1 || || Elongin A; F-box protein; ubiquitin-protein ligase; role in protein ubiquitination and ubiquitin-dependent protein catabolism; rat catheter biofilm induced || 1 -0.03 -0.24 -0.42 -0.87 0.72 0.41 0.57 0.71 -0.08 0.02 1.71 1.14 0.84 0.53 0.76 0.49
3093 || orf19.5855 || MBP1 || || Putative component of the MBF transcription complex involved in G1/S cell-cycle progression; non-periodic mRNA expression; predicted, conserved MBF binding sites upstream of G1/S-regulated genes || 1 -0.25 -0.20 -0.37 -0.78 0.59 0.41 0.13 0.29 0.19 0.03 0.61 0.72 0.57 0.45 0.63 0.38
3094 || orf19.7034 || || || Putative eIF4E-associated protein;, accelerates mRNA degradation by promoting decapping; Spider biofilm repressed || 1 -0.34 -0.30 -0.34 -0.35 0.38 0.55 0.33 0.37 0.26 -0.00 0.76 1.01 0.52 0.26 0.84 0.56
3095 || orf19.3213 || || || Protein of unknown function; Spider biofilm induced || 1 0.05 -0.18 -0.55 -0.69 0.90 0.93 0.44 0.03 0.08 -0.29 1.40 1.22 0.85 0.31 1.46 0.18
3096 || orf19.1610 || || || Putative protein of unknown function, transcription is activated in the presence of elevated CO2 || 1 0.05 0.38 -0.51 -0.98 1.34 0.94 0.47 0.36 0.54 -0.12 0.85 1.08 0.75 0.78 1.28 0.64
3097 || orf19.1610 || || || Putative protein of unknown function, transcription is activated in the presence of elevated CO2 || 1 0.05 -0.16 -0.46 -0.91 1.04 1.20 0.12 0.55 0.17 -0.31 0.94 0.84 0.46 0.38 1.60 0.75
3098 || orf19.1504 || || || Putative patatin-like phospholipase; fungal-specific (no human or murine homolog) || 1 0.28 -0.03 -0.77 -0.89 1.11 1.46 0.39 0.50 -0.12 -0.40 1.56 1.42 0.38 0.34 1.58 1.57
3099 || orf19.1252 || YME1 || || Ortholog(s) have ATP-dependent peptidase activity || 1 0.25 0.25 -0.61 -0.89 0.78 0.56 0.56 0.24 -0.04 -0.16 1.05 0.57 0.01 0.33 1.02 0.99
3100 || orf19.7179 || || || Ortholog(s) have role in intracellular sequestering of iron ion, iron-sulfur cluster assembly, protein maturation and mitochondrial matrix localization || 1 -0.05 -0.08 -0.74 -0.93 0.93 0.74 0.48 0.45 0.43 0.19 0.86 0.70 0.06 0.23 1.03 1.04
3101 || orf19.1198 || || || Predicted mitochondrial intermembrane space protein of unknown function; possibly an essential gene, disruptants not obtained by UAU1 method || 1 -0.17 -0.26 -0.70 -0.70 1.64 1.24 0.75 0.48 0.24 0.29 1.39 0.82 0.09 0.49 1.72 0.73
3102 || orf19.1610 || || || Putative protein of unknown function, transcription is activated in the presence of elevated CO2 || 1 -0.16 -0.34 -0.16 -0.18 0.64 0.78 0.30 0.24 0.10 -0.49 0.90 0.46 0.32 0.10 0.90 0.44
3103 || orf19.1610 || || || Putative protein of unknown function, transcription is activated in the presence of elevated CO2 || 1 -0.29 -0.32 -0.08 -0.35 1.24 1.21 0.45 0.20 0.25 -0.43 1.06 0.63 0.54 0.09 1.03 0.48
3104 || orf19.7527 || || || Ortholog of C. dubliniensis CD36 : Cd36_25130, C. parapsilosis CDC317 : CPAR2_800100, Candida tenuis NRRL Y-1498 : CANTEDRAFT_107256 and Debaryomyces hansenii CBS767 : DEHA2E18370g || 1 -0.13 -0.02 0.10 -0.23 0.85 0.74 0.46 -0.09 0.21 -0.15 0.62 0.35 0.23 0.09 0.98 0.65
3105 || orf19.5651 || || || Ortholog(s) have histone demethylase activity (H3-dimethyl-K4 specific), histone demethylase activity (H3-trimethyl-K4 specific) activity || 1 0.11 0.07 -0.06 -0.85 1.54 1.65 0.26 -0.42 0.13 -0.91 1.15 0.98 0.59 0.23 1.71 1.01
3106 || orf19.3245 || || || Ortholog of C. dubliniensis CD36 : Cd36_26090, C. parapsilosis CDC317 : CPAR2_801510, Candida tenuis NRRL Y-1498 : CANTEDRAFT_137093 and Debaryomyces hansenii CBS767 : DEHA2F20548g || 1 -0.11 -0.18 -0.01 -0.19 0.84 0.77 0.10 -0.02 0.43 -0.43 0.63 0.79 0.06 0.23 1.14 0.38
3107 || orf19.5394.1 || || || Ortholog(s) have role in mitochondrial respiratory chain complex IV assembly and cytosol, integral to mitochondrial inner membrane, mitochondrial intermembrane space, nucleus localization || 1 0.05 0.03 -0.06 -0.44 1.55 1.34 0.27 0.57 -0.04 -0.06 1.66 1.04 -0.35 -0.02 1.81 1.04
3108 || orf19.4878 || || || Protein of unknown function; Hap43-repressed; rat catheter biofilm repressed || 1 0.09 0.17 -0.05 0.01 0.55 0.60 0.01 0.29 -0.09 -0.18 0.77 0.65 0.00 0.12 0.78 0.28
3109 || orf19.2260 || || || Putative transcription factor with zinc finger DNA-binding motif || 1 -0.06 0.04 0.04 -0.34 0.72 0.90 0.21 0.28 -0.23 0.32 0.31 0.64 0.10 0.38 0.49 0.25
3110 || orf19.2528 || || || Putative RNA polymerase III transcription factor (TFIIIB) subunit; flucytosine repressed || 1 0.06 -0.03 0.07 -0.18 0.96 0.60 0.13 -0.05 0.04 0.26 0.49 0.77 0.26 0.09 0.69 0.72
3111 || orf19.5513 || PRP45 || || Protein required for pre-mRNA splicing; Spider biofilm induced || 1 0.20 0.01 0.11 -0.35 1.00 1.25 0.24 0.06 -0.29 0.41 0.45 0.71 0.20 0.24 1.06 0.80
3112 || orf19.1198 || || || Predicted mitochondrial intermembrane space protein of unknown function; possibly an essential gene, disruptants not obtained by UAU1 method || 1 -0.02 0.21 -0.19 -0.31 1.29 1.41 0.21 0.56 0.03 0.19 0.69 0.92 0.00 0.36 1.34 1.15
3113 || orf19.6260 || || || Ubiquitin-specific protease; cleaves ubiquitin from ubiquitinated proteins; Spider biofilm induced || 1 0.42 0.44 -0.45 -0.34 1.06 1.41 -0.02 0.25 -0.03 0.89 1.05 0.86 0.23 0.41 1.14 1.00
3114 || orf19.6260 || || || Ubiquitin-specific protease; cleaves ubiquitin from ubiquitinated proteins; Spider biofilm induced || 1 0.34 0.08 -0.05 0.54 1.10 1.40 0.29 0.27 -0.17 0.81 1.06 1.26 0.18 0.39 0.96 0.95
3115 || orf19.2366 || || || Has domain(s) with predicted DNA binding activity and role in DNA integration || 1 0.13 0.44 -0.29 0.49 0.56 1.28 0.43 -0.05 0.38 0.18 0.99 0.53 0.73
3116 || orf19.5277 || || || Ortholog(s) have role in nuclear-transcribed mRNA catabolic process, 3'-5' exonucleolytic nonsense-mediated decay, protein ubiquitination and cytoplasm, nucleolus, polysome localization || 1 0.38 0.39 0.06 0.04 0.66 1.14 0.33 -0.09 0.30 0.76 1.00 0.52 0.64 0.84 0.88
3117 || orf19.3658 || || || Ortholog(s) have role in protein folding in endoplasmic reticulum and Golgi apparatus, integral to endoplasmic reticulum membrane, mitochondrion localization || 1 -0.09 0.31 -0.26 -0.24 0.58 1.00 0.40 0.22 0.17 0.17 0.82 0.72 0.68 0.68 1.06 1.11
3118 || orf19.1913 || || || Protein of unknown function; flow model biofilm induced || 1 -0.14 0.06 -0.04 -0.14 0.53 0.86 0.62 0.33 0.23 0.28 0.86 0.89 0.45 0.42 0.65 1.33
3119 || orf19.5765 || NUP82 || || Linker nucleoporin of the nuclear pore complex; role in mRNA andexport from nucleus, protein import into nucleus, ribosomal large subunit export from nucleus, ribosomal small subunit export from nucleus; rat catheter biofilm repressed || 1 -0.08 0.01 -0.10 -0.28 0.47 0.51 0.23 0.18 0.17 0.18 0.50 0.61 0.31 0.49 0.35 0.70
3120 || orf19.5855 || MBP1 || || Putative component of the MBF transcription complex involved in G1/S cell-cycle progression; non-periodic mRNA expression; predicted, conserved MBF binding sites upstream of G1/S-regulated genes || 1 0.07 -0.15 -0.03 -0.31 0.63 0.65 0.37 0.31 0.19 -0.00 0.76 0.48 0.50 0.62 0.54 0.92
3121 || orf19.686 || || || Protein of unknown function; regulated by Nrg1 || 1 -0.04 -0.14 -0.10 -0.22 0.69 0.79 0.24 0.14 0.06 0.06 0.48 0.54 0.27 0.25 0.11 0.79
3122 || orf19.4232 || PTH1 || || Putative gluconate transport protein; antigenic during human oral infection; possibly an essential gene, disruptants not obtained by UAU1 method || 1 0.20 0.16 0.06 0.03 0.21 0.44 0.45 0.32 0.34 0.21 0.92 0.58 0.08 0.28 0.41 0.88
3123 || orf19.2009 || PEX12 || || Ortholog(s) have ubiquitin-protein ligase activity, role in protein import into peroxisome matrix and integral to peroxisomal membrane localization || 1 0.23 0.19 -0.02 0.01 0.58 0.44 0.52 0.42 0.69 0.29 1.05 1.04 0.27 0.65 1.12 0.93
3124 || orf19.2433 || || || Ortholog of C. dubliniensis CD36 : Cd36_05790, C. parapsilosis CDC317 : CPAR2_103730, Pichia stipitis Pignal : PICST_28344, Candida tropicalis MYA-3404 : CTRG_04275 and Candida albicans WO-1 : CAWG_00795 || 1 0.61 0.17 -0.17 0.19 1.44 0.95 0.53 0.80 0.42 0.42 1.75 1.49 0.52 0.99 0.85 1.25
3125 || orf19.504 || || || Ortholog(s) have ATP-dependent 3'-5' DNA helicase activity, role in nucleosome mobilization and Ino80 complex, cytosol localization || 1 0.36 0.31 0.22 0.01 0.56 0.57 0.42 0.21 0.31 0.16 0.70 0.73 0.03 0.23 0.38 0.54
3126 || orf19.2104 || || || Ortholog(s) have chaperone binding activity, role in aerobic respiration, iron-sulfur cluster assembly and mitochondrion localization || 1 0.33 0.12 -0.03 0.16 0.65 0.20 0.52 0.36 0.21 0.28 0.72 0.64 -0.22 0.47 0.74 0.66
3127 || orf19.371 || || || Ortholog of C. dubliniensis CD36 : Cd36_40110, C. parapsilosis CDC317 : CPAR2_402300, Candida tenuis NRRL Y-1498 : CANTEDRAFT_94507 and Debaryomyces hansenii CBS767 : DEHA2F05588g || 1 0.12 0.28 -0.20 -0.11 1.04 0.80 0.80 1.02 0.38 0.08 1.29 0.61 0.23 0.99 1.12 0.89
3128 || orf19.3930 || YUH2 || || Putative ubiquitin C-terminal hydrolase; sumoylation target || 1 0.27 0.39 -0.06 -0.32 0.89 0.46 0.61 0.90 0.41 0.26 1.17 0.57 0.30 0.63 0.90 0.78
3129 || orf19.4186 || PCT1 || || Putative choline-phosphate cytidylyl transferase, antigenic during human oral infection || 1 0.44 0.40 -0.17 -0.35 0.74 0.68 0.23 0.36 -0.12 0.10 0.79 0.68 0.48 0.19 0.50 0.28
3130 || orf19.4400 || || || Has domain(s) with predicted role in anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process, regulation of mitotic metaphase/anaphase transition and anaphase-promoting complex localization || 1 0.84 0.57 -0.22 -0.29 0.93 0.88 0.32 1.09 0.21 0.37 1.05 1.11 0.86 0.37 1.42 0.43
3131 || orf19.4626 || || || Ortholog(s) have role in TOR signaling cascade, positive regulation of transcription from RNA polymerase I promoter and cytosol, extrinsic to membrane, nucleus localization || 1 0.88 0.56 -0.89 -0.11 1.31 0.90 0.70 0.77 0.31 0.63 1.24 0.67 0.93 0.47 1.53 0.63
3132 || orf19.2901 || NUP60 || || Ortholog of S. cerevisiae Nup60p; a subunit of the nuclear pore complex; mutants are viable || 1 0.82 0.82 -0.39 -0.40 1.55 0.99 0.52 0.20 0.37 0.90 1.14 0.58 0.88 0.70 1.57 0.62
3133 || orf19.6407 || || || Ortholog(s) have role in ribosomal large subunit biogenesis and cytoplasm, cytosolic large ribosomal subunit, preribosome, large subunit precursor localization || 1 0.38 0.05 -0.08 -0.20 1.41 0.70 0.51 0.48 0.53 0.56 1.02 0.77 0.34 0.51 0.99 0.88
3134 || orf19.2368 || || || Predicted component of U5 snRNP; Spider biofilm induced || 1 0.31 0.66 -0.87 -0.65 1.75 1.40 0.75 0.43 0.79 0.74 1.20 1.05 0.50 0.73 1.65 1.25
3135 || orf19.3321 || MRS7 || || Member of the LETM1-like protein family, mitochondrial membrane protein || 1 0.33 0.56 -0.27 -0.11 1.07 1.20 0.61 0.68 0.32 0.58 0.75 0.63 0.30 0.65 0.95 0.61
3136 || orf19.6625 || || || Ortholog(s) have acetyltransferase activator activity, histone binding activity and role in double-strand break repair via nonhomologous end joining, nucleosome assembly, positive regulation of histone acetylation || 1 0.31 0.15 -0.29 -0.32 1.26 1.27 0.33 0.76 0.29 0.85 1.05 0.61 0.22 0.64 0.99 0.79
3137 || orf19.3250 || || || Ortholog(s) have RNA binding activity, role in mRNA cis splicing, via spliceosome and U1 snRNP, U2-type prespliceosome localization || 1 0.28 0.39 -0.18 -0.65 1.64 1.52 0.58 0.48 0.18 0.57 1.07 1.09 0.35 0.65 1.12 0.64
3138 || orf19.5531 || CDC37 || || Chaperone for Crk1p; interacts with Crk1p kinase domain and with Sti1p; putative phosphorylation site at Ser14; functional homolog of S. cerevisiae Cdc37p; likely to be essential for growth; regulated by Gcn2p and Gcn4p || 1 0.42 0.48 -0.23 -0.63 2.06 1.75 0.67 1.05 0.27 0.43 1.39 1.06 0.50 0.28 1.93 0.84
3139 || orf19.4258 || || || Puttaive pre-mRNA polyadenylation factor; heterozygous null mutant exhibits hypersensitivity to parnafungin and cordycepin in the C. albicans fitness test || 1 0.30 0.44 -0.13 0.15 1.09 0.97 0.74 0.60 0.17 0.53 1.07 0.83 0.53 0.16 1.10 0.30
3140 || orf19.5430 || BUD21 || || Small-subunit processome component; repressed by prostaglandins || 1 0.90 0.36 -0.24 -0.25 2.36 1.98 1.45 1.37 0.11 1.56 1.45 1.07 0.49 0.63 2.10 0.21
3141 || orf19.3102 || CTA6 || || Protein that activates transcription in 1-hybrid assay in S. cerevisiae || 1 0.43 -0.05 -0.07 0.05 0.99 0.70 0.61 0.56 0.50 0.34 0.62 0.54 0.39 0.45 1.16 0.48
3142 || orf19.705 || GCN5 || || Putative histone acetyltransferase; mutation confers hypersensitivity to 5-fluorouracil (5-FU); possibly an essential gene, disruptants not obtained by UAU1 method || 1 0.09 0.23 0.31 0.25 0.98 0.87 0.19 0.59 0.13 0.31 1.15 0.41 0.12 0.46 0.92 0.58
3143 || orf19.7183 || || || Ortholog(s) have role in protein folding in endoplasmic reticulum and ER membrane protein complex localization || 1 0.30 0.36 0.25 0.08 0.81 0.73 0.26 0.24 -0.09 0.24 0.82 0.38 0.08 0.22 0.91 0.57
3144 || orf19.515 || || || Has domain(s) with predicted nucleic acid binding, zinc ion binding activity || 1 0.40 0.93 0.21 0.02 1.85 1.75 0.69 0.87 -0.25 0.53 1.16 0.51 0.51 0.45 1.56 0.76
3145 || orf19.5394.1 || || || Ortholog(s) have role in mitochondrial respiratory chain complex IV assembly and cytosol, integral to mitochondrial inner membrane, mitochondrial intermembrane space, nucleus localization || 1 0.74 0.87 -0.09 -0.25 2.16 1.93 0.39 0.78 0.27 -0.03 1.93 0.92 0.35 0.03 1.46 1.00
3146 || orf19.2965.1 || || || Protein of unknown function; similar to human SERF2; gene has an alternatively spliced intron || 1 0.15 0.45 0.24 -0.08 0.82 1.10 0.60 0.56 0.45 -0.01 1.13 0.77 0.51 0.74 0.98 0.56
3147 || orf19.7527 || || || Ortholog of C. dubliniensis CD36 : Cd36_25130, C. parapsilosis CDC317 : CPAR2_800100, Candida tenuis NRRL Y-1498 : CANTEDRAFT_107256 and Debaryomyces hansenii CBS767 : DEHA2E18370g || 1 0.33 0.31 0.08 0.22 1.01 0.96 0.67 0.19 0.48 0.11 0.96 0.73 0.80 0.52 1.34 0.73
3148 || orf19.864 || || || Ortholog(s) have role in nuclear-transcribed mRNA catabolic process, 3'-5' exonucleolytic nonsense-mediated decay and cytosol, polysome localization || 1 0.17 0.31 0.33 -0.16 1.00 0.76 0.64 0.33 0.55 0.47 0.55 0.59 0.86 0.68 1.15 0.53
3149 || orf19.267 || || || Protein required for normal filamentous growth; mRNA binds She3 || 1 0.41 0.48 0.03 -0.13 1.36 0.82 0.72 0.52 0.44 0.44 0.67 0.34 0.70 0.50 0.57 0.59
3150 || orf19.7449 || || || Ortholog(s) have role in mitochondrial genome maintenance, plasmid maintenance and cytosol, mitochondrion localization || 1 0.58 0.67 0.19 -0.22 2.28 1.52 1.04 0.50 0.88 0.54 0.86 0.58 0.71 0.69 1.15 1.25
3151 || orf19.267 || || || Protein required for normal filamentous growth; mRNA binds She3 || 1 0.52 0.38 0.27 -0.33 1.21 1.02 0.64 0.43 0.18 0.34 0.35 0.35 0.09 0.75 0.59 0.84
3152 || orf19.1045 || || || Putative U2 snRNP protein; Hap43p-induced gene; mutation confers hypersensitivity to 5-fluorocytosine (5-FC), 5-fluorouracil (5-FU), and tubercidin (7-deazaadenosine) || 1 0.76 0.76 0.51 -0.16 1.47 1.95 1.23 1.06 0.59 1.08 1.73 0.70 1.00 1.03 0.68
3153 || orf19.5609 || || || Ortholog of C. dubliniensis CD36 : Cd36_63840, C. parapsilosis CDC317 : CPAR2_601510, Debaryomyces hansenii CBS767 : DEHA2A06270g and Pichia stipitis Pignal : PICST_31363 || 1 0.59 0.28 0.26 -0.14 1.22 1.07 0.62 0.49 -0.01 0.75 0.87 0.57 0.67 1.17 0.91 0.71
3154 || orf19.3250 || || || Ortholog(s) have RNA binding activity, role in mRNA cis splicing, via spliceosome and U1 snRNP, U2-type prespliceosome localization || 1 0.43 0.32 0.00 -0.09 1.06 0.89 0.29 0.40 0.44 0.84 0.58 1.18 0.50 0.43 0.91 0.61
3155 || orf19.2111 || || || Ortholog(s) have core RNA polymerase II binding transcription factor activity and role in transcription elongation from RNA polymerase II promoter, transcriptional start site selection at RNA polymerase II promoter || 1 0.38 0.47 0.04 0.19 1.02 0.58 0.38 0.35 0.09 0.54 0.83 0.51 0.19 -0.10 1.08 0.68
3156 || orf19.2982 || || || Ortholog(s) have protein complex scaffold, protein kinase activator activity || 1 0.37 0.65 0.10 0.27 1.64 1.20 0.79 -0.12 0.72 -0.03 0.71 1.10 0.42 0.68 0.90 0.72
3157 || orf19.457 || || || Ortholog(s) have ubiquitin-specific protease activity, role in protein deubiquitination, ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway and cytosol localization || 1 0.33 0.45 0.03 -0.08 0.95 0.60 0.31 0.26 0.43 -0.03 0.48 0.57 0.30 0.45 0.77 0.51
3158 || orf19.6797 || || || Ortholog of C. dubliniensis CD36 : Cd36_86960, C. parapsilosis CDC317 : CPAR2_808800, Candida tenuis NRRL Y-1498 : CANTEDRAFT_113621 and Debaryomyces hansenii CBS767 : DEHA2F02486g || 1 0.05 0.16 0.13 0.04 0.61 0.38 0.25 0.11 0.18 -0.15 0.45 0.60 0.18 0.53 0.44 0.45
3159 || orf19.5227 || || || Chaperone component; involved in assembly of alpha subunits into the 20S proteasome; flow model biofilm induced || 1 0.49 0.64 -0.10 0.03 1.29 1.10 0.69 0.71 0.10 -0.27 1.12 0.10 0.81 0.82 0.63 0.78
3160 || orf19.2361 || SPT10 || || Ortholog(s) have sequence-specific DNA binding activity || 1 0.84 1.20 0.32 0.28 1.59 1.59 1.33 0.79 0.28 0.29 1.38 -0.05 1.30 0.83 1.99 1.14
3161 || orf19.2107.1 || STF2 || || Protein involved in ATP biosynthesis; repressed in hyphae; repressed by Efg1, Hap43; transcript upregulated in clinical isolates from HIV+ patients with oral candidiasis; rat catheter, flow model and Spider biofilm induced || 1 1.38 1.72 0.10 -0.78 3.95 2.66 2.86 1.77 1.51 -0.96 2.20 0.54 2.77 1.44 3.40 2.03
3162 || orf19.2107.1 || STF2 || || Protein involved in ATP biosynthesis; repressed in hyphae; repressed by Efg1, Hap43; transcript upregulated in clinical isolates from HIV+ patients with oral candidiasis; rat catheter, flow model and Spider biofilm induced || 1 1.54 1.90 0.40 -0.51 4.09 3.02 3.13 2.21 1.76 -0.68 2.52 1.04 2.99 2.04 3.72 2.31
3163 || orf19.864 || || || Ortholog(s) have role in nuclear-transcribed mRNA catabolic process, 3'-5' exonucleolytic nonsense-mediated decay and cytosol, polysome localization || 1 0.21 0.31 0.02 -0.13 0.76 0.40 0.69 0.37 0.14 0.16 0.35 0.25 0.47 0.37 0.70 0.70
3164 || orf19.738 || MYO5 || || Class I myosin; nonessential; role in cortical actin patch polarity and polar budding; required for hyphal growth, white-opaque switch; regulatory phosphorylation on S366; downregulated on adherence to polystyrene || 1 0.25 0.43 -0.04 0.04 0.74 0.50 0.47 0.25 0.16 -0.29 0.43 0.32 0.43 0.28 1.03 0.64
3165 || orf19.27 || || || Ortholog of C. dubliniensis CD36 : Cd36_20860, C. parapsilosis CDC317 : CPAR2_104250, Candida tenuis NRRL Y-1498 : CANTEDRAFT_115100 and Debaryomyces hansenii CBS767 : DEHA2E10450g || 1 0.77 0.72 -0.33 -0.10 1.30 0.61 1.05 0.89 0.11 -0.44 0.87 -0.05 0.79 0.23 1.14 0.86
3166 || orf19.3102 || CTA6 || || Protein that activates transcription in 1-hybrid assay in S. cerevisiae || 1 0.30 0.39 -0.44 -0.32 1.20 0.30 0.59 0.69 0.28 0.34 0.82 0.25 0.68 0.50 1.26 0.11
3167 || orf19.6871 || || || Protein of unknown function; Hap43-induced; flow model biofilm repressed || 1 0.50 0.51 -0.31 -0.38 1.64 0.56 0.98 0.68 -0.08 0.28 1.06 0.52 1.23 0.74 1.97 0.19
3168 || orf19.1444 || || || Ortholog(s) have phosphatidylinositol-4,5-bisphosphate binding activity, role in actin cortical patch assembly, actin filament organization, endocytosis and actin cortical patch, mating projection tip localization || 1 0.56 0.44 -0.23 -0.26 0.91 0.51 0.60 0.37 0.15 -0.07 0.46 0.37 0.86 0.43 1.11 0.33
3169 || orf19.3428 || || || Protein of unknown function; flow model biofilm induced || 1 0.75 0.91 -0.25 -0.29 1.10 0.57 1.16 0.53 0.06 -0.15 1.28 0.73 1.27 0.50 2.02 0.61
3170 || orf19.7046 || MET28 || || Predicted bZIP domain-containing transcription factor; protein induced during the mating process; possibly essential, disruptants not obtained by UAU1 method; Hap43-repressed; rat catheter biofilm induced || 1 0.58 0.55 -0.20 -0.32 0.90 0.76 0.79 0.51 0.24 -0.18 0.97 0.48 1.01 0.73 2.11 0.31
3171 || orf19.6220 || || || Ortholog(s) have role in positive regulation of transcription elongation from RNA polymerase II promoter and CCR4-NOT core complex localization || 1 0.38 0.38 -0.12 -0.29 0.71 0.50 0.47 0.16 -0.03 0.25 0.80 0.42 0.67 0.22 1.19 0.44
3172 || orf19.7449 || || || Ortholog(s) have role in mitochondrial genome maintenance, plasmid maintenance and cytosol, mitochondrion localization || 1 0.69 0.27 -0.32 -0.34 1.46 0.72 0.62 0.20 0.51 0.27 0.78 0.36 0.65 0.61 1.13 0.02
3173 || orf19.188 || || || Ortholog of Candida albicans WO-1 : CAWG_04234 || 1 0.99 1.68 -0.04 -0.56 2.12 0.58 1.54 1.07 0.51 0.54 2.18 0.48 1.64 0.02 1.66 0.59
3174 || orf19.1252 || YME1 || || Ortholog(s) have ATP-dependent peptidase activity || 1 0.76 0.67 -0.13 -1.00 1.45 0.65 0.99 0.64 0.53 0.23 1.41 0.38 0.68 0.05 1.26 1.10
3175 || orf19.4470 || || || Protein of unknown function; Hap43-repressed gene || 1 0.41 0.60 -0.38 -0.94 0.99 0.31 0.96 0.50 0.25 0.30 1.30 0.59 0.46 0.05 1.18 0.39
3176 || orf19.4375 || || || Ortholog(s) have S-adenosylmethionine-dependent methyltransferase activity, role in chromatin silencing at rDNA, nicotinamide metabolic process and cytosol localization || 1 0.39 0.49 -0.62 -1.01 1.13 0.84 0.39 0.75 -0.07 0.07 1.02 0.75 0.41 -0.15 0.93 0.34
3177 || orf19.4439.1 || || || Ortholog(s) have role in nucleotide-excision repair, phosphorylation of RNA polymerase II C-terminal domain, transcription from RNA polymerase II promoter and core TFIIH complex, cytosol, holo TFIIH complex localization || 1 0.46 0.58 -0.37 -0.41 1.09 0.79 0.76 1.02 -0.12 0.28 1.44 0.96 0.07 -0.26 1.30 0.31
3178 || orf19.4439.1 || || || Ortholog(s) have role in nucleotide-excision repair, phosphorylation of RNA polymerase II C-terminal domain, transcription from RNA polymerase II promoter and core TFIIH complex, cytosol, holo TFIIH complex localization || 1 0.67 0.25 -0.64 -0.31 1.51 0.71 0.84 0.98 0.11 0.28 1.56 0.80 0.31 0.08 1.52 0.61
3179 || orf19.674 || || || Ortholog(s) have U6 snRNA binding, pre-mRNA binding activity and role in mRNA cis splicing, via spliceosome, spliceosomal snRNP assembly || 1 0.36 0.53 -0.34 -0.25 1.31 1.13 1.05 0.51 0.33 0.12 1.86 1.15 0.77 -0.32 0.90 0.47
3180 || orf19.3213 || || || Protein of unknown function; Spider biofilm induced || 1 -0.06 0.15 -0.47 -0.16 1.44 0.95 0.58 0.35 0.34 -0.07 1.46 1.35 0.73 -0.29 1.41 0.61
3181 || orf19.1590 || || || Ortholog of C. dubliniensis CD36 : Cd36_18970, C. parapsilosis CDC317 : CPAR2_212800, Debaryomyces hansenii CBS767 : DEHA2F08690g and Candida guilliermondii ATCC 6260 : PGUG_01488 || 1 0.21 0.10 -0.25 -0.30 0.72 0.42 0.56 0.32 0.32 0.16 0.35 0.57 0.17 0.27 1.05 0.39
3182 || orf19.4127 || || || Ortholog(s) have actin filament binding activity, role in actin cortical patch localization, actin filament bundle assembly, endocytosis and actin cortical patch localization || 1 -0.07 0.21 0.05 -0.27 0.86 0.42 0.36 0.30 0.10 -0.14 1.06 0.56 0.37 0.29 0.97 0.58
3183 || orf19.1938 || || || Ortholog of S.pombe SPCC825.05c; a predicted splicing coactivator; transcription repressed in azole-resistant strain overexpressing CDR1 and CDR2; induced by benomyl treatment || 1 0.05 1.07 -0.26 -0.07 1.19 1.07 0.36 0.09 0.27 0.88 1.58 0.99 0.95 0.78 1.66 0.80
3184 || orf19.5277 || || || Ortholog(s) have role in nuclear-transcribed mRNA catabolic process, 3'-5' exonucleolytic nonsense-mediated decay, protein ubiquitination and cytoplasm, nucleolus, polysome localization || 1 0.52 0.71 -0.26 -0.27 1.14 1.54 0.91 0.06 0.29 0.48 1.36 0.22 1.27 0.72 1.21 -0.34
3185 || orf19.5513 || PRP45 || || Protein required for pre-mRNA splicing; Spider biofilm induced || 1 0.90 0.99 -0.41 -0.17 1.65 2.08 1.23 0.57 0.33 0.58 1.51 1.34 1.65 0.28 1.67 0.09
3186 || orf19.4964 || || || Ortholog(s) have role in cellular bud site selection, mRNA export from nucleus, mRNA splicing, via spliceosome and RES complex localization || 1 0.87 0.62 0.33 -0.07 1.64 1.85 1.14 0.94 -0.01 0.74 1.26 1.10 1.91 0.74 1.50 -0.17
3187 || orf19.4464 || SEN15 || || Similar to delta subunit of tRNA splicing endonuclease; increased transcription is observed upon fluphenazine treatment || 1 1.46 1.49 0.28 -0.56 1.23 1.35 0.82 0.76 0.31 1.04 1.42 0.69 1.47 0.24 0.95 0.12
3188 || orf19.3858 || || || Protein of unknown function; rat catheter and Spider biofilm induced || 1 0.72 0.57 -0.09 -0.23 0.93 0.92 0.46 0.89 -0.01 0.18 1.48 0.28 0.95 0.01 0.99 0.73
3189 || orf19.6075 || || || Putative CCR4-Not complex transcription factor; ortholog of S. cerevisiae Cdc36; Hap43-repressed gene || 1 0.40 0.22 -0.05 -0.11 0.43 0.36 0.22 0.49 -0.13 0.13 0.79 0.19 0.10 -0.03 0.37 0.32
3190 || orf19.2842 || GZF3 || || GATA-type transcription factor; oxidative stress-induced via Cap1; mutant has abnormal colony morphology and altered sensitivity to fluconazole, LiCl, and copper; Spider biofilm induced || 1 0.00 0.24 -0.90 -0.71 1.94 1.02 1.30 1.14 0.92 1.46 1.07 1.18 1.85 0.34 2.38 -0.16
3191 || orf19.2842 || GZF3 || || GATA-type transcription factor; oxidative stress-induced via Cap1; mutant has abnormal colony morphology and altered sensitivity to fluconazole, LiCl, and copper; Spider biofilm induced || 1 0.40 0.31 -0.82 -0.15 2.81 1.77 1.75 1.23 1.42 1.49 1.45 1.29 2.31 1.12 2.84 0.53
3192 || orf19.3272 || || || Ortholog(s) have chaperone binding activity, role in box C/D snoRNP assembly, protein folding and R2TP complex, cytoplasm, nucleus localization || 1 0.30 0.67 -0.33 -0.29 1.21 0.50 0.94 0.57 0.43 0.71 1.41 0.76 1.54 0.46 1.28 0.23
3193 || orf19.2749 || || || BTB/POZ domain protein; induced by Mnl1 under weak acid stress; flow model biofilm induced; Spider biofilm induced || 1 0.02 0.12 -0.46 0.25 1.30 0.44 1.01 0.67 0.47 0.41 1.09 0.92 1.16 0.90 1.02 -0.43
3194 || orf19.1936 || SNF1 || || Essential protein; functional homolog of S. cerevisiae Snf1p regulator of sugar metabolism; constitutively expressed; Thr208 phosphorylation may have regulatory role; up-regulation associated with azole resistance; has polyhistidine tract || 1 0.06 0.07 -0.17 -0.20 0.10 0.04 -0.09 0.05 -0.14 -0.05 0.52 0.33 0.05 0.23 0.76 0.47
3195 || orf19.4914 || || || Ortholog(s) have role in cellular response to DNA damage stimulus || 1 0.35 0.27 -0.34 -0.45 0.69 -0.35 0.02 0.47 -0.31 0.06 1.07 0.51 0.07 0.37 0.92 0.91
3196 || orf19.6638 || PTC4 || || Type PP2C serine/threonine phosphatase; localized to mitochondria; mutation causes sensitivity to sodium, potassium and azole drugs; decreased expression in hyphae compared to yeast-form cells || 1 -0.05 -0.05 -0.50 -0.39 0.49 0.15 -0.33 0.11 -0.38 0.05 1.03 0.16 0.11 0.34 0.64 0.70
3197 || orf19.6638 || PTC4 || || Type PP2C serine/threonine phosphatase; localized to mitochondria; mutation causes sensitivity to sodium, potassium and azole drugs; decreased expression in hyphae compared to yeast-form cells || 1 -0.11 -0.18 -0.72 -0.87 0.29 0.13 -0.05 0.02 -0.38 -0.09 0.98 0.34 0.15 0.43 0.72 0.96
3198 || orf19.3315 || CTA9 || || Protein required for normal filamentous growth; induced during the mating process; mRNA binds She3; activates transcription in 1-hybrid assay in S. cerevisiae || 1 -0.01 0.07 -0.50 -0.57 1.04 0.91 -0.30 0.07 -0.28 -0.51 0.54 0.45 0.27 -0.03 0.47 0.85
3199 || orf19.921 || HMS1 || || hLh domain Myc-type transcript factor; required for morphogenesis induced by elevated temperature or Hsp90 compromise; acts downstream of Pcl1; Spider biofilm induced || 1 -0.51 -0.15 -0.56 -1.63 1.76 1.09 0.25 -0.12 0.03 -0.62 1.28 1.11 -0.13 -0.37 1.17 1.82
3200 || orf19.921 || HMS1 || || hLh domain Myc-type transcript factor; required for morphogenesis induced by elevated temperature or Hsp90 compromise; acts downstream of Pcl1; Spider biofilm induced || 1 -0.70 -0.67 -1.38 -2.05 1.38 0.92 0.14 0.22 -0.38 -1.29 1.62 0.97 -0.30 -0.70 1.79 1.66
3201 || orf19.2839 || CIRT4B || || Cirt family transposase; transcript repressed in an azole-resistant strain that overexpresses CDR1 and CDR2; Hap43-repressed; flow model biofilm induced || 1 -1.64 -0.69 -2.17 -2.02 1.99 2.52 0.24 -0.15 -0.43 -0.62 1.46 1.29 0.79 -0.29 1.65 1.70
3202 || orf19.6193 || TAF145 || || Protein similar to S. cerevisiae Taf145p, a component of RNA polymerase II transcription factor TFIID; flucytosine repressed; likely to be essential for growth, based on an insertional mutagenesis strategy || 1 -0.15 -0.12 -0.35 -0.49 0.45 0.24 0.03 0.06 -0.30 -0.32 0.24 0.40 0.28 0.05 0.58 0.20
3203 || orf19.6987 || DNM1 || || Putative dynamin-related GTPase; transcript upregulated inbRHE model of oral candidiasis; transcript regulated by Nrg1, Mig1, and Tup1 || 1 -0.28 -0.09 -0.84 -0.63 0.42 0.54 0.26 0.05 -0.19 0.08 0.57 0.45 -0.16 -0.24 0.72 0.18
3204 || orf19.4375 || || || Ortholog(s) have S-adenosylmethionine-dependent methyltransferase activity, role in chromatin silencing at rDNA, nicotinamide metabolic process and cytosol localization || 1 -0.32 -0.07 -0.82 -0.90 0.90 1.04 -0.06 0.26 -0.08 0.57 0.74 0.84 -0.12 0.37 0.45 0.11
3205 || orf19.7443 || || || Ortholog of C. dubliniensis CD36 : Cd36_86510, C. parapsilosis CDC317 : CPAR2_206110, Candida tenuis NRRL Y-1498 : CANTEDRAFT_112184 and Debaryomyces hansenii CBS767 : DEHA2F17292g || 1 0.26 0.15 -0.69 -0.99 1.02 0.78 0.57 0.29 -0.34 0.62 0.77 0.63 -0.35 0.23 0.71 0.38
3206 || orf19.2654 || RMS1 || || Putative lysine methyltransferase; Hap43-induced; protein induced during mating; possibly essential, disruptants not obtained by UAU1 method; rat catheter and Spider biofilm induced || 1 0.57 -0.05 -0.64 -1.31 1.31 1.90 0.73 -0.02 -0.51 0.78 1.10 1.06 0.20 0.04 1.57 0.60
3207 || orf19.264 || || || Has domain(s) with predicted protein kinase binding activity and role in regulation of cyclin-dependent protein serine/threonine kinase activity || 1 -0.16 -0.18 -0.73 -0.73 1.03 1.11 -0.29 0.03 -0.47 0.28 0.89 0.56 -0.09 0.17 1.17 0.85
3208 || orf19.4186 || PCT1 || || Putative choline-phosphate cytidylyl transferase, antigenic during human oral infection || 1 0.25 0.17 -0.74 -0.94 0.67 0.44 0.05 0.19 -0.22 0.06 0.60 0.44 0.14 0.14 0.62 0.65
3209 || orf19.6425 || SKI2 || || Ortholog(s) have role in cellular response to cadmium ion, detoxification of cadmium ion, nuclear-transcribed mRNA catabolic process, 3'-5' exonucleolytic nonsense-mediated decay, nuclear-transcribed mRNA catabolic process, non-stop decay || 1 -0.04 -0.03 -0.50 -0.42 0.33 0.25 0.03 0.09 -0.11 0.03 0.16 0.24 -0.02 0.30 0.17 0.35
3210 || orf19.6195 || || || Ortholog(s) have 3'-5'-exoribonuclease activity || 1 -0.38 -0.23 -0.73 -0.73 0.38 0.54 0.24 0.05 -0.34 0.19 0.46 0.10 0.01 0.24 0.41 0.47
3211 || orf19.1214 || || || Ortholog(s) have metalloaminopeptidase activity, role in protein initiator methionine removal involved in protein maturation and cytosol, nucleus localization || 1 -0.53 -0.51 -1.06 -0.97 0.81 0.91 0.34 0.27 -0.57 0.08 1.30 0.71 0.11 0.50 0.89 0.53
3212 || orf19.4542 || || || Ortholog(s) have cyclin-dependent protein serine/threonine kinase inhibitor activity and role in phosphorylation of RNA polymerase II C-terminal domain, regulation of mitotic cell cycle, transcription from RNA polymerase II promoter || 1 -0.17 -0.18 -0.69 -0.91 0.34 0.48 0.34 -0.02 -0.11 0.05 0.80 0.50 -0.13 0.53 0.73 0.62
3213 || orf19.7179 || || || Ortholog(s) have role in intracellular sequestering of iron ion, iron-sulfur cluster assembly, protein maturation and mitochondrial matrix localization || 1 -0.17 -0.31 -0.88 -1.15 1.07 0.54 0.47 0.04 0.20 0.64 0.90 0.49 -0.19 0.61 1.19 0.74
3214 || orf19.4414 || || || Ortholog of C. dubliniensis CD36 : Cd36_45590, C. parapsilosis CDC317 : CPAR2_501450, Candida tenuis NRRL Y-1498 : CANTEDRAFT_105024 and Debaryomyces hansenii CBS767 : DEHA2D12364g || 1 0.14 -0.47 -1.05 -1.00 1.30 0.82 0.56 -0.07 0.05 0.20 1.17 0.32 0.27 0.42 0.86 0.57
3215 || orf19.686 || || || Protein of unknown function; regulated by Nrg1 || 1 -0.08 -0.01 -0.28 -0.63 0.74 0.77 0.35 0.13 0.15 0.09 0.65 0.52 0.43 0.35 0.20 0.37
3216 || orf19.1028 || ELA1 || || Elongin A; F-box protein; ubiquitin-protein ligase; role in protein ubiquitination and ubiquitin-dependent protein catabolism; rat catheter biofilm induced || 1 -0.44 0.18 -0.40 -0.57 0.60 0.86 -0.05 0.10 0.14 -0.05 1.20 0.73 0.47 0.42 0.41 0.76
3217 || orf19.6194 || || || Ortholog of C. dubliniensis CD36 : Cd36_06640, C. parapsilosis CDC317 : CPAR2_208220, Candida tenuis NRRL Y-1498 : CANTEDRAFT_136902 and Debaryomyces hansenii CBS767 : DEHA2F26730g || 1 -0.12 -0.07 -0.14 -0.32 0.34 0.38 -0.03 0.22 -0.14 -0.41 0.76 0.63 0.13 0.40 0.24 0.89
3218 || orf19.3583 || || || Ortholog(s) have role in protein export from nucleus, regulation of chromatin silencing at telomere, ribosomal small subunit export from nucleus and cytosol, nuclear pore localization || 1 -0.21 -0.25 -0.21 -0.13 0.23 0.37 0.04 0.49 -0.03 0.08 0.83 0.65 -0.14 0.37 0.26 0.57
3219 || orf19.2297 || ARL3 || || Putative Ras superfamily GTPase; induced by nitric oxide independent of Yhb1p || 1 -0.32 -0.30 -0.36 -0.23 0.21 0.29 0.33 0.70 -0.17 0.31 1.21 0.78 0.26 0.41 0.27 0.73
3220 || orf19.3583 || || || Ortholog(s) have role in protein export from nucleus, regulation of chromatin silencing at telomere, ribosomal small subunit export from nucleus and cytosol, nuclear pore localization || 1 -0.22 -0.21 -0.17 -0.18 0.41 0.30 0.30 0.37 0.11 0.20 0.93 0.74 0.19 0.47 0.35 0.39
3221 || orf19.7165 || MED9 || || RNA polymerase II mediator complex subunit; Hap43p-repressed gene || 1 -0.21 -0.08 -0.09 -0.20 0.57 0.47 0.31 0.55 0.02 0.17 0.99 0.73 0.09 0.57 0.25 0.05
3222 || orf19.1386 || || || Ortholog(s) have SNAP receptor activity and role in ER to Golgi vesicle-mediated transport, retrograde vesicle-mediated transport, Golgi to ER, vesicle fusion || 1 -0.28 -0.21 -0.07 -0.33 0.46 0.55 0.00 0.46 -0.04 0.56 1.08 0.72 -0.03 0.12 0.69 0.03
3223 || orf19.1039 || BET4 || || Ortholog(s) have Rab geranylgeranyltransferase activity and role in ER to Golgi vesicle-mediated transport, protein geranylgeranylation, protein targeting to membrane || 1 -0.04 -0.14 -0.28 -0.00 0.54 0.25 0.08 0.31 -0.07 0.52 0.66 0.60 -0.12 0.06 0.23 0.40
3224 || orf19.2104 || || || Ortholog(s) have chaperone binding activity, role in aerobic respiration, iron-sulfur cluster assembly and mitochondrion localization || 1 0.03 0.31 0.03 0.06 0.62 0.23 0.21 0.27 -0.11 0.26 0.95 0.56 -0.16 0.24 0.65 0.61
3225 || orf19.2907.1 || || || Ortholog(s) have chromatin DNA binding activity, role in positive regulation of transcription from RNA polymerase II promoter by pheromones, threonylcarbamoyladenosine metabolic process and EKC/KEOPS complex, nuclear chromatin localization || 1 -0.08 0.02 0.01 -0.29 0.72 0.24 0.32 0.24 -0.39 0.30 0.89 0.20 -0.05 0.29 0.49 0.83
3226 || orf19.3659 || || || Putative CTD phosphatase; role in dephosphorylation of RNA polymerase II C-terminal domain, transcription from RNA polymerase II promoter; flow model biofilm induced || 1 0.25 -0.13 -0.04 -0.17 0.69 0.59 0.56 0.51 -0.06 -0.03 1.22 0.32 0.02 1.24 0.80 0.86
3227 || orf19.1462 || SMP2 || || Putative Mg2+-dependent phosphatidate phosphatase; transcript regulated by Nrg1 || 1 0.05 0.23 0.35 0.14 0.74 0.67 0.25 0.30 0.30 0.20 0.44 0.96 -0.55 0.54 0.68 0.99
3228 || orf19.1462 || SMP2 || || Putative Mg2+-dependent phosphatidate phosphatase; transcript regulated by Nrg1 || 1 0.09 -0.14 0.02 -0.34 0.83 0.76 0.13 0.38 0.23 0.03 0.68 0.72 -0.39 0.52 0.71 0.75
3229 || orf19.1519 || || || Protein of unknown function; Hap43-repressed gene || 1 0.15 0.07 -0.06 -0.21 0.47 0.22 0.43 0.42 0.18 -0.36 0.33 0.77 -0.14 0.11 0.70 0.78
3230 || orf19.5601 || || || Ortholog(s) have extracellular region localization || 1 0.13 0.08 -0.20 -0.34 0.77 0.40 0.38 0.26 0.37 -0.28 0.58 0.83 -0.23 0.17 0.73 0.90
3231 || orf19.1877 || || || Ortholog(s) have cytoplasm, nucleus localization || 1 -0.13 -0.22 -0.39 -0.27 0.51 0.16 0.66 0.03 0.13 -0.08 0.68 0.84 -0.01 0.57 0.85 0.93
3232 || orf19.3245 || || || Ortholog of C. dubliniensis CD36 : Cd36_26090, C. parapsilosis CDC317 : CPAR2_801510, Candida tenuis NRRL Y-1498 : CANTEDRAFT_137093 and Debaryomyces hansenii CBS767 : DEHA2F20548g || 1 -0.33 -0.55 -0.37 -0.52 0.75 0.88 0.14 -0.05 0.50 -0.38 0.87 0.98 -0.16 -0.02 1.26 0.87
3233 || orf19.2574 || || || Ortholog(s) have Golgi apparatus localization || 1 -0.94 -0.60 -0.43 -0.45 0.98 1.65 -0.04 0.15 0.33 0.58 1.96 1.79 -0.22 0.83 1.81 1.85
3234 || orf19.757 || || || Ortholog of S. cerevisiae : YPR089W, C. glabrata CBS138 : CAGL0K08008g, C. dubliniensis CD36 : Cd36_04600, C. parapsilosis CDC317 : CPAR2_105630 and Candida tenuis NRRL Y-1498 : CANTEDRAFT_129373 || 1 -0.09 -0.12 -0.11 -0.52 0.21 0.40 0.22 0.06 0.01 0.22 0.58 0.80 -0.09 0.39 0.64 0.92
3235 || orf19.5621 || || || Putative protein of unknown function; mutation confers hypersensitivity to amphotericin B; overlaps orf19.5621 || 1 0.02 -0.16 -0.12 -0.41 0.41 0.87 0.01 -0.28 -0.21 0.19 0.44 0.83 -0.21 -0.05 0.99 0.80
3236 || orf19.4465 || || || Protein of unknown function; Spider biofilm induced || 1 0.09 0.01 -0.08 -0.38 0.70 0.88 0.48 -0.30 0.29 0.05 0.23 0.77 0.14 0.36 0.64 0.57
3237 || orf19.6431 || || || Protein of unknown function; Spider biofilm induced || 1 -0.23 -0.47 -0.29 -0.24 0.58 0.84 0.71 0.25 0.11 0.63 0.25 0.67 0.35 0.81 0.75 0.43
3238 || orf19.6866 || || || Putative U1-70K component of the U1 snRNP, involved in splicing; ortholog of S. cerevisiae SNP1; downregulated upon adherence to polystyrene || 1 -0.08 -0.09 -0.26 -0.11 0.21 0.33 0.04 0.21 -0.02 0.43 0.14 0.33 0.53 0.39 0.34 0.27
3239 || orf19.4861 || || || Protein of unknown function; rat catheter biofilm repressed || 1 0.04 -0.20 -0.25 -0.14 0.31 0.23 0.07 0.56 -0.02 0.28 -0.13 0.28 0.45 0.46 0.68 0.35
3240 || orf19.3772 || || || Predicted ORF in Assemblies 19, 20 and 21; merged with orf19.3773 in Assembly 21 || 1 -0.22 -0.13 -0.26 -0.23 0.22 0.19 0.32 0.43 0.27 0.46 0.26 0.57 0.38 1.02 0.93 0.41
3241 || orf19.2805 || PEX8 || || Putative peroxisomal biogenesis factor; expression regulated during planktonic growth || 1 -0.21 0.05 -0.34 -0.12 -0.16 0.06 0.21 0.34 0.33 0.12 0.10 0.71 0.43 0.52 0.58 0.32
3242 || orf19.5586 || || || Ortholog(s) have phosphatidylinositol-3,5-bisphosphate 5-phosphatase activity, role in phosphatidylinositol dephosphorylation and PAS complex, cytosol, extrinsic to membrane, fungal-type vacuole membrane localization || 1 -0.06 0.00 -0.09 -0.28 -0.07 0.19 0.40 0.34 0.80 0.21 0.10 0.47 0.40 0.82 0.22 0.77
3243 || orf19.3487 || || || Ortholog of C. dubliniensis CD36 : Cd36_33330, C. parapsilosis CDC317 : CPAR2_701980, Debaryomyces hansenii CBS767 : DEHA2C15840g and Pichia stipitis Pignal : PICST_31066 || 1 -0.27 -0.41 -0.39 -0.44 -0.32 0.22 0.40 0.87 1.13 0.47 0.64 0.70 0.49 0.48 0.41 1.09
3244 || orf19.1458 || || || Ortholog(s) have tRNA-specific adenosine deaminase activity, role in tRNA modification and cytoplasm, nucleus localization || 1 -0.06 -0.51 -0.47 -0.35 0.09 0.60 0.31 0.46 0.80 0.23 0.61 0.92 0.57 0.68 0.64 0.45
3245 || orf19.5725 || || || Ortholog(s) have guanyl-nucleotide exchange factor activity, role in autophagic vacuole fusion, protein targeting to vacuole, vesicle docking and Mon1-Ccz1 complex localization || 1 -0.07 -0.11 -0.10 -0.55 0.08 -0.05 0.56 0.19 0.75 0.21 0.52 0.62 0.45 0.40 0.81 0.65
3246 || orf19.4628 || || || Putative cleavage and polyadenylation factor; heterozygous null mutant exhibits hypersensitivity to parnafungin and cordycepin in the C. albicans fitness test; possibly an essential gene, disruptants not obtained by UAU1 method || 1 -0.31 -0.26 0.32 -0.63 0.09 0.48 0.69 0.40 0.49 0.45 0.83 0.86 0.74 0.41 1.24 1.04
3247 || orf19.422 || SPT20 || || Putative transcription factor; downregulated upon adherence to polystyrene; flucytosine repressed || 1 -0.02 -0.07 -0.00 -0.41 0.33 0.25 0.32 0.11 0.25 0.04 0.25 0.47 0.52 0.03 0.46 0.31
3248 || orf19.3422 || FMP27 || || Putative mitochondrial protein; mRNA binds She3 || 1 -0.49 -0.38 -0.28 -0.52 0.78 1.07 1.15 0.74 0.99 -0.34 1.32 0.65 2.23 1.04 1.12 1.10
3249 || orf19.1266 || || || Protein of unknown function; transcript detected on high-resolution tiling arrays || 1 -0.10 -0.01 -0.09 0.03 0.43 0.68 0.76 0.47 0.44 -0.07 0.51 0.38 0.81 0.55 0.81 0.20
3250 || orf19.6754 || || || Protein of unknown function; Spider biofilm induced || 1 -0.06 0.02 -0.07 -0.05 0.11 0.03 0.25 0.14 -0.23 0.01 0.72 0.65 0.60 0.23 0.70 0.52
3251 || orf19.2789 || || || Ortholog of C. dubliniensis CD36 : Cd36_07040, C. parapsilosis CDC317 : CPAR2_208700, Candida tenuis NRRL Y-1498 : CANTEDRAFT_108836 and Debaryomyces hansenii CBS767 : DEHA2F25674g || 1 -0.25 -0.58 -0.67 0.11 0.01 0.37 0.38 0.50 -0.03 0.01 0.98 0.76 0.71 0.28 1.11 0.77
3252 || orf19.3678 || || || Ortholog of C. dubliniensis CD36 : Cd36_02060, C. parapsilosis CDC317 : CPAR2_106200, Candida tenuis NRRL Y-1498 : CANTEDRAFT_96322 and Debaryomyces hansenii CBS767 : DEHA2C02310g || 1 -0.09 -0.20 -0.73 -0.26 0.41 0.60 1.18 0.38 0.36 -0.20 1.77 0.76 1.63 0.61 2.08 1.29
3253 || orf19.3678 || || || Ortholog of C. dubliniensis CD36 : Cd36_02060, C. parapsilosis CDC317 : CPAR2_106200, Candida tenuis NRRL Y-1498 : CANTEDRAFT_96322 and Debaryomyces hansenii CBS767 : DEHA2C02310g || 1 -0.78 -0.45 -0.76 -0.44 -0.10 0.69 0.86 0.10 0.29 0.03 1.11 0.95 1.33 0.33 1.36 1.61
3254 || orf19.2582 || || || Ortholog(s) have role in cytoplasmic translation, ribosome-associated ubiquitin-dependent protein catabolic process and RQC complex, cytosol, cytosolic large ribosomal subunit localization || 1 -0.09 -0.02 -0.43 -0.31 0.24 0.11 -0.02 0.03 0.27 0.06 0.64 0.72 0.40 0.03 0.80 0.61
3255 || orf19.6754 || || || Protein of unknown function; Spider biofilm induced || 1 -0.24 -0.34 -0.69 -0.73 0.39 0.08 0.10 0.06 -0.42 -0.18 0.80 0.73 0.56 0.27 1.29 0.63
3256 || orf19.1973 || HAP5 || || Component of CCAAT-binding transcription factor; roles in filamentous growth, low-iron induction of FRP1; regulates genes involved in respiratory growth; functional homolog of S. cerevisiae Hap5p; Cap1p-dependent expression in low iron || 1 0.02 -0.09 -0.55 -0.70 0.13 -0.09 0.27 0.17 -0.18 0.02 0.46 0.44 0.69 0.17 0.87 0.28
3257 || orf19.1760 || RAS1 || || RAS signal transduction GTPase; regulates cAMP and MAP kinase pathways; role in hyphal induction, virulence, apoptosis, heat-shock sensitivity; nonessential; plasma membrane-localized; complements viability of S. cerevisiae ras1 ras2 mutant || 1 -0.07 -0.07 -0.80 -0.51 0.37 0.28 0.16 -0.06 -0.10 0.07 0.20 0.45 1.22 0.28 0.94 -0.08
3258 || orf19.3252 || DAL81 || || Zn(II)2Cys6 transcription factor; ortholog of S. cerevisiae Dal81, involved in the regulation of nitrogen-degradation genes; required for yeast cell adherence to silicone substrate; Spider biofilm induced || 1 -0.08 0.02 -0.97 -0.53 0.60 0.70 0.37 0.02 0.17 0.44 0.30 0.84 1.21 0.35 0.94 0.25
3259 || orf19.422 || SPT20 || || Putative transcription factor; downregulated upon adherence to polystyrene; flucytosine repressed || 1 -0.13 0.05 -0.66 -0.60 0.49 0.21 0.45 0.08 0.12 0.18 0.48 0.47 0.63 -0.05 0.86 0.18
3260 || orf19.1492 || PRP39 || || Putative component of the U1 snRNP; involved in splicing; Hap43-induced gene; Spider biofilm induced || 1 0.13 0.08 -0.88 -0.87 0.84 0.35 0.37 0.12 -0.08 0.13 0.77 0.97 0.77 0.41 0.99 0.06
3261 || orf19.3023 || NGG1 || || Ortholog(s) have histone acetyltransferase activity and role in cellular response to cadmium ion, detoxification of cadmium ion, histone acetylation, regulation of transcription from RNA polymerase II promoter || 1 -0.11 -0.03 -0.35 -0.50 0.65 0.23 0.03 0.13 -0.12 0.31 0.69 0.95 0.50 0.40 1.12 0.31
3262 || orf19.6871 || || || Protein of unknown function; Hap43-induced; flow model biofilm repressed || 1 0.06 -0.01 -0.43 -0.29 1.13 0.64 0.35 0.23 -0.16 0.24 0.47 0.46 0.64 0.70 1.41 0.20
3263 || orf19.606 || || || Protein of unknown function; Hap43-induced; Spider biofilm induced || 1 -0.00 -0.15 -0.10 -0.23 0.64 0.20 0.24 -0.02 -0.06 0.33 0.30 0.29 0.69 0.59 0.75 0.20
3264 || orf19.4844 || || || Ortholog(s) have RNA binding, polynucleotide adenylyltransferase activity, protein binding, bridging activity || 1 -0.00 0.00 -0.11 -0.51 0.42 0.22 0.31 0.36 -0.15 0.43 0.72 0.40 1.05 0.43 0.73 0.44
3265 || orf19.3858 || || || Protein of unknown function; rat catheter and Spider biofilm induced || 1 -0.15 -0.09 -0.13 -0.39 0.46 0.73 0.17 0.10 -0.25 0.29 0.90 0.50 0.80 0.45 0.58 0.19
3266 || orf19.2231 || || || Protein of unknown function; Spider biofilm induced || 1 -0.01 0.08 -0.51 -0.48 0.27 1.39 0.45 0.31 -0.19 0.20 1.04 1.37 1.90 1.00 2.95 0.61
3267 || orf19.2231 || || || Protein of unknown function; Spider biofilm induced || 1 -0.08 0.16 -0.60 -0.16 0.10 0.90 0.20 0.04 -0.17 0.40 0.77 0.94 1.31 0.52 2.42 0.58
3268 || orf19.7046 || MET28 || || Predicted bZIP domain-containing transcription factor; protein induced during the mating process; possibly essential, disruptants not obtained by UAU1 method; Hap43-repressed; rat catheter biofilm induced || 1 0.06 0.10 -0.51 -0.59 0.40 0.35 0.64 0.21 0.05 -0.18 0.71 0.26 0.47 0.48 1.86 0.32
3269 || orf19.3571 || || || Ortholog of C. dubliniensis CD36 : Cd36_19870, C. parapsilosis CDC317 : CPAR2_209420, Candida tenuis NRRL Y-1498 : CANTEDRAFT_100922 and Debaryomyces hansenii CBS767 : DEHA2D11176g || 1 0.37 0.06 -0.77 -1.02 1.19 0.44 0.51 0.86 -0.60 0.44 1.48 -0.03 0.47 -0.02 1.50 0.42
3270 || orf19.713 || || || Ortholog(s) have role in apoptotic process and cytoplasm, nucleus localization || 1 0.00 0.41 -0.78 -0.86 0.83 0.26 0.92 0.72 -0.28 -0.08 1.36 0.13 0.82 0.13 1.35 0.61
3271 || orf19.2516 || || || Has domain(s) with predicted role in cell redox homeostasis || 1 0.01 0.01 -0.49 -0.43 0.31 0.21 0.44 0.50 -0.18 -0.22 1.00 0.54 0.65 -0.06 0.92 0.36
3272 || orf19.5757 || || || Ortholog(s) have cytoplasm, nucleus localization || 1 -0.13 -0.25 -0.62 -0.59 0.45 0.44 0.43 0.54 -0.08 -0.33 0.73 0.13 0.46 -0.21 0.85 0.29
3273 || orf19.6393 || || || Putative Arf3p GTPase activating protein; Hap43p-repressed gene; possibly an essential gene, disruptants not obtained by UAU1 method || 1 -0.45 -0.03 -0.71 -0.84 1.22 0.40 0.50 0.70 0.18 -0.05 0.82 0.15 0.97 0.30 0.82 0.81
3274 || orf19.2605 || PRK1 || || Putative protein serine/threonine kinase; mutants sensitive to growth on hydrogen peroxide medium || 1 -0.36 -0.29 -0.43 -0.98 0.52 0.24 0.45 0.29 0.03 -0.34 0.63 0.25 0.60 0.53 0.91 0.49
3275 || orf19.5247 || || || Ortholog(s) have cytoplasm localization || 1 -0.50 -0.56 -0.58 -0.56 0.72 0.35 0.44 0.23 0.12 -0.06 0.54 0.20 0.22 0.38 0.82 0.37
3276 || orf19.4262 || || || Ortholog(s) have mRNA binding activity and role in cellular protein complex localization, establishment of mitochondrion localization, nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay || 1 -0.41 -0.33 -0.68 -0.45 0.41 0.11 0.25 0.27 -0.13 -0.38 0.41 0.36 0.38 0.20 0.70 1.00
3277 || orf19.719 || || || Ortholog(s) have ubiquitin-protein ligase activity || 1 0.39 0.31 -0.10 -0.17 0.23 -0.08 0.42 0.35 -0.17 -0.55 0.43 -0.06 0.74 0.15 0.73 1.25
3278 || orf19.719 || || || Ortholog(s) have ubiquitin-protein ligase activity || 1 0.34 0.38 -0.25 -0.38 0.41 0.23 0.35 0.31 -0.00 -0.29 0.65 -0.19 0.75 0.49 0.62 1.03
3279 || orf19.2026 || UBP13 || || Ortholog of S. cerevisiae Ubp13; putative ubiquitin carboxyl-terminal hydrolase; flow model biofilm induced; rat catheter biofilm repressed || 1 0.15 0.14 0.17 -0.04 0.08 0.61 0.26 0.03 0.10 -0.08 0.28 -0.01 0.49 0.17 0.23 0.68
3280 || orf19.2272 || AFT2 || || Putative Aft domain transcription factor; role in regulation of iron metabolism, oxidative stress, adhesion, hyphal growth, colony morphology, virulence; complements S. cerevisiae aft1 mutation; Spider biofilm induced || 1 0.37 0.36 0.25 -0.03 0.22 0.83 0.46 0.20 0.10 -0.42 0.53 0.48 1.00 0.17 0.46 0.85
3281 || orf19.1090 || || || Ortholog of C. parapsilosis CDC317 : CPAR2_601110, C. dubliniensis CD36 : Cd36_64660, Candida tenuis NRRL Y-1498 : CANTEDRAFT_119969 and Lodderomyces elongisporus NRLL YB-4239 : LELG_04881 || 1 0.37 0.69 -0.25 0.46 0.29 -0.19 -0.08 -0.01 0.44 0.55 0.93 0.45 0.22 1.17
3282 || orf19.6448 || || || Protein of unknown function; Spider biofilm repressed || 1 0.29 0.35 0.27 -0.04 0.55 0.27 0.10 -0.05 -0.05 -0.10 0.58 0.28 0.21 0.14 0.60 0.94
3283 || orf19.4127 || || || Ortholog(s) have actin filament binding activity, role in actin cortical patch localization, actin filament bundle assembly, endocytosis and actin cortical patch localization || 1 0.03 0.05 0.18 0.02 0.56 0.67 0.15 0.21 -0.04 -0.32 0.74 0.23 0.48 0.21 0.85 0.72
3284 || orf19.6482 || || || Protein of unknown function; induced by nitric oxide independent of Yhb1p; regulated by Sef1, Sfu1, and Hap43; rat catheter biofilm induced || 1 -0.04 0.14 0.57 0.45 0.24 0.20 -0.59 0.70 0.69 0.61 1.12 1.09
3285 || orf19.593 || FGR32 || || Protein similar to S. cerevisiae Swa2p; induced upon adherence to polystyrene; transposon mutation affects filamentous growth; Hap43p-repressed gene || 1 0.10 0.01 0.29 -0.07 0.25 0.07 0.04 0.08 0.23 0.06 0.37 0.23 0.35 0.27 0.50 0.67
3286 || orf19.1877 || || || Ortholog(s) have cytoplasm, nucleus localization || 1 -0.20 0.12 -0.34 -0.04 0.59 0.48 0.29 -0.31 0.48 0.01 0.54 0.79 0.32 0.13 0.41 0.33
3287 || orf19.2647 || ZCF14 || || Putative Zn(II)2Cys6 transcription factor; caspofungin induced || 1 0.98 0.62 -0.57 -0.68 0.90 0.54 0.85 -0.20 1.41 0.65 1.46 1.22 1.06 0.40 0.76 0.30
3288 || orf19.1303 || || || Ortholog(s) have translation release factor activity, role in mitochondrial translational termination and mitochondrion localization || 1 -0.16 0.14 0.34 -0.08 1.19 0.03 0.92 0.07 0.85 0.15 1.04 0.94 0.34 0.46 0.86 0.05
3289 || orf19.4621 || || || Ortholog(s) have cytoplasmic mRNA processing body localization || 1 -0.02 0.20 0.21 -0.16 0.39 -0.02 0.46 0.09 0.37 0.09 0.40 0.27 0.37 0.19 0.05 0.31
3290 || orf19.7102 || || || Has domain(s) with predicted exonuclease activity, nucleic acid binding activity and intracellular localization || 1 0.22 0.74 0.24 -0.28 0.93 -0.11 0.42 0.18 0.71 0.65 1.02 1.01 0.80 0.08 0.03 0.61
3291 || orf19.2103 || || || Ortholog of Candida albicans WO-1 : CAWG_03811 || 1 0.05 0.29 0.69 0.17 1.02 0.25 0.49 -0.04 0.56 0.81 0.74 0.95 0.28 0.30 0.29
3292 || orf19.1039 || BET4 || || Ortholog(s) have Rab geranylgeranyltransferase activity and role in ER to Golgi vesicle-mediated transport, protein geranylgeranylation, protein targeting to membrane || 1 0.22 0.15 0.14 0.18 0.65 0.36 0.46 0.21 0.10 0.50 0.80 0.99 0.25 -0.13 0.08 0.43
3293 || orf19.2222 || || || Putative casein kinase; plasma membrane-localized || 1 0.06 -0.20 -0.61 -0.18 0.58 0.79 0.14 -0.30 -0.60 0.33 0.89 0.65 0.99 -0.16 0.92 1.04
3294 || orf19.6276 || || || Protein of unknown function; rat catheter biofilm repressed || 1 -0.05 -0.04 -0.36 -0.15 0.47 0.33 0.02 -0.22 0.09 -0.17 0.21 0.22 0.55 -0.58 0.63 0.69
3295 || orf19.3222 || || || Predicted vacuolar protein; rat catheter biofilm repressed; flow model biofilm repressed || 1 -0.07 -0.01 -0.43 -0.17 0.51 0.39 -0.09 0.17 -0.45 -0.44 0.43 0.55 0.45 0.35 0.28 0.38
3296 || orf19.5227 || || || Chaperone component; involved in assembly of alpha subunits into the 20S proteasome; flow model biofilm induced || 1 0.26 0.31 -0.41 -0.15 0.77 0.55 -0.12 0.24 -0.30 -0.36 0.37 -0.03 0.64 0.72 0.34 0.54
3297 || orf19.2585 || || || Ortholog of Candida albicans WO-1 : CAWG_01548 || 1 0.02 0.17 -0.39 -0.37 0.46 -0.33 0.17 -0.17 0.76 0.30 0.70 0.67 -0.41 1.13
3298 || orf19.5701 || || || Ortholog(s) have role in DNA replication initiation, establishment of mitotic sister chromatid cohesion and condensed nuclear chromosome kinetochore localization || 1 0.18 -0.34 -0.40 -0.80 0.92 0.43 -0.22 0.12 0.34 -0.20 0.33 0.76 0.42 0.84 -0.40 1.23
3299 || orf19.6296 || VPS22 || || ESCRT-II complex protein with a role in multivesicular body (MVB) trafficking; required for processing of Rim8p; Hap43p-repressed gene || 1 -0.14 0.25 0.03 -0.35 0.33 0.53 0.04 0.12 0.37 -0.33 0.38 0.34 0.31 0.54 -0.26 0.37
3300 || orf19.5812 || || || Ortholog of S. cerevisiae Ett1, a nuclear protein that inhibits replication of Brome mosaic virus; early-stage flow model biofilm induced || 1 0.68 0.75 -1.25 -1.42 1.23 1.29 0.91 0.73 0.49 -0.27 0.97 0.40 0.51 0.16 -0.23 0.49
3301 || orf19.3515 || || || Putative 3-hydroxyanthranilic acid dioxygenase, involved in NAD biosynthesis; Hap43p-repressed gene || 1 0.47 0.58 -0.15 -0.96 1.19 0.90 0.24 0.22 -0.25 -0.88 0.39 0.31 -0.08 -0.14 0.57 0.73
3302 || orf19.2219 || ORF298 || || Predicted ORF in retrotransposon Tca3; similar to Gag-Pol; a-specific transcript, alpha-factor induced; rat catheter biofilm repressed; mRNA binds She3 || 1 0.02 -0.09 0.09 -0.25 1.02 1.02 0.58 0.47 0.10 -0.58 0.97 0.54 0.56 0.17 0.32 0.86
3303 || orf19.4436 || GPX3 || || Putative glutathione peroxidase involved in Cap1p-dependent oxidative stress response, required for Cap1p oxidation in response to H2O2; planktonic growth-induced || 1 0.02 0.02 -0.34 -0.80 1.02 1.24 0.57 0.36 -0.52 -0.95 0.86 0.08 0.66 0.44 0.75 0.70
3304 || orf19.2324 || UBA4 || || Putative ubiquitin activating protein; Hap43-repressed; induced by prostaglandins; clade-associated gene expression || 1 -0.08 -0.14 -0.37 -0.75 0.60 0.51 0.41 0.40 -0.24 -0.77 0.42 -0.07 0.12 0.04 0.14 1.11
3305 || orf19.5346 || || || Ortholog(s) have role in transcription from RNA polymerase II promoter and transcription factor TFIID complex localization || 1 0.02 -0.13 -0.15 -0.55 0.44 0.45 0.19 0.39 0.03 -0.33 0.55 0.19 0.35 0.24 0.06 0.69
3306 || orf19.1067 || GPM2 || || Putative phosphoglycerate mutase; repressed in hyphae; macrophage/pseudohyphal-repressed; induced by high levels of peroxide stress, farnesol; flow model biofilm induced; rat catheter and Spider biofilm repressed || 1 0.20 0.23 -0.60 -1.97 2.00 1.68 0.45 0.66 0.24 -1.46 1.24 0.20 0.81 0.07 -0.34 0.98
3307 || orf19.1067 || GPM2 || || Putative phosphoglycerate mutase; repressed in hyphae; macrophage/pseudohyphal-repressed; induced by high levels of peroxide stress, farnesol; flow model biofilm induced; rat catheter and Spider biofilm repressed || 1 0.04 0.17 -0.81 -2.05 1.83 1.81 0.47 0.69 0.17 -1.47 1.16 0.47 0.44 0.12 0.14 1.33
3308 || orf19.2219 || ORF298 || || Predicted ORF in retrotransposon Tca3; similar to Gag-Pol; a-specific transcript, alpha-factor induced; rat catheter biofilm repressed; mRNA binds She3 || 1 -0.06 -0.26 -0.39 -0.54 1.03 1.02 0.31 0.40 0.25 -0.87 0.79 0.25 0.01 -0.22 0.04 0.70
3309 || orf19.1802 || OFD1 || || Putative prolyl hydroxylase family member; regulates Ume6p stability in response to oxygen; inhibited by hypoxia; repressed by prostaglandins; Spider biofilm induced || 1 0.23 0.22 -0.46 -1.04 1.14 1.48 0.30 0.48 -0.10 -0.62 1.10 0.74 -0.23 -0.57 0.06 1.45
3310 || orf19.2366 || || || Has domain(s) with predicted DNA binding activity and role in DNA integration || 1 -0.17 -0.23 -0.82 -1.67 1.00 1.61 -0.12 0.24 0.34 -0.30 0.59 0.70 0.08 1.13
3311 || orf19.354 || || || Ortholog(s) have aminopeptidase activity, role in protein processing, protein stabilization and extrinsic to mitochondrial inner membrane, nucleus localization || 1 -0.30 -0.27 -0.43 -0.94 0.47 0.55 -0.00 0.17 0.19 -0.29 0.49 0.53 -0.24 -0.05 -0.06 0.71
3312 || orf19.1841 || || || Protein of unknown function; Hap43-induced gene || 1 0.25 0.19 0.26 0.39 0.61 -0.74 0.20 0.88 -0.20 0.46 0.08 1.12 -0.02 1.08 0.26 1.22
3313 || orf19.5043 || || || Ortholog of C. dubliniensis CD36 : Cd36_43610, C. parapsilosis CDC317 : CPAR2_403770, Debaryomyces hansenii CBS767 : DEHA2G16962g and Pichia stipitis Pignal : PICST_30926 || 1 0.25 0.29 0.37 0.19 0.43 -0.53 0.42 0.68 0.34 0.71 0.28 0.68 0.15 0.78 0.38 0.69
3314 || orf19.4252 || || || Ortholog(s) have protein serine/threonine kinase activity || 1 0.30 0.33 0.76 0.27 0.24 -0.02 0.77 0.65 0.36 0.35 0.16 0.29 -0.07 0.30 0.32 0.43
3315 || orf19.6552 || || || Flavin-linked sulfhydryl oxidase; predicted localization to endoplasmic reticulum lumen; involved in disulfide bond formation within the ER; Spider biofilm induced || 1 0.08 0.01 0.42 0.37 0.12 0.02 0.61 0.35 0.56 0.22 0.29 0.40 0.03 0.36 0.13 0.30
3316 || orf19.3625 || || || Has domain(s) with predicted zinc ion binding activity || 1 0.16 0.14 0.90 1.02 0.45 -0.47 0.48 0.65 0.53 0.38 0.54 1.00 -0.13 0.78 0.16 0.43
3317 || orf19.6255 || || || Putative protein of unknown function; Hap43p-repressed gene || 1 0.12 0.07 0.32 0.35 0.25 0.16 0.24 0.41 0.36 -0.01 -0.03 0.74 0.30 0.52 0.18 0.66
3318 || orf19.4117 || || || Ortholog of C. dubliniensis CD36 : Cd36_20450, C. parapsilosis CDC317 : CPAR2_104160, Candida tenuis NRRL Y-1498 : CANTEDRAFT_95516 and Debaryomyces hansenii CBS767 : DEHA2F05192g || 1 0.28 0.05 0.55 0.21 0.18 -0.08 0.29 0.38 0.20 0.07 0.17 0.47 0.04 0.54 0.31 0.64
3319 || orf19.3572 || || || Ortholog of C. dubliniensis CD36 : Cd36_19880, Candida tenuis NRRL Y-1498 : CANTEDRAFT_117672, Debaryomyces hansenii CBS767 : DEHA2D11154g and Pichia stipitis Pignal : PICST_59570 || 1 0.67 0.20 0.34 0.66 0.15 -0.28 0.38 0.41 0.30 0.34 -0.00 0.58 0.34 0.78 0.66 0.33
3320 || orf19.1371 || || || Ortholog of C. dubliniensis CD36 : Cd36_23880, C. parapsilosis CDC317 : CPAR2_806590, Candida tenuis NRRL Y-1498 : CANTEDRAFT_92769 and Debaryomyces hansenii CBS767 : DEHA2B13376g || 1 0.58 0.48 0.54 0.40 0.14 -0.15 0.54 0.77 0.45 0.10 -0.08 0.56 0.35 0.54 0.56 0.43
3321 || orf19.4904 || || || Ortholog(s) have nucleosome binding activity, role in chromatin silencing at telomere, histone exchange and Swr1 complex, cytosol, nuclear chromosome, telomeric region localization || 1 0.62 0.45 0.47 0.32 0.37 0.08 0.25 0.24 -0.00 -0.00 0.04 0.43 0.36 0.43 0.45 0.44
3322 || orf19.2129 || || || Ortholog of S. cerevisiae Spo71; a meiosis-specific protein required for spore wall formation during sporulation in S. cerevisiae; possibly an essential gene, disruptants not obtained by UAU1 method || 1 0.04 0.15 0.15 0.30 0.22 -0.08 0.18 0.27 0.11 0.03 -0.05 0.38 0.08 0.19 0.45 0.09
3323 || orf19.6605 || || || Ortholog(s) have fungal-type vacuole, mitochondrion localization || 1 0.30 0.27 0.53 0.58 0.31 0.17 0.14 0.23 0.64 0.44 -0.35 0.02 0.13 0.60 0.73 0.19
3324 || orf19.3519 || SUA72 || || Predicted transcription factor; induced during planktonic growth, whereas related SUA71 is downregulated || 1 0.26 0.55 0.34 0.62 0.02 0.00 0.43 0.50 0.65 0.58 -0.26 0.26 -0.01 0.80 0.44 0.49
3325 || orf19.5237 || VPH2 || || Ortholog(s) have role in vacuolar acidification, vacuolar proton-transporting V-type ATPase complex assembly and endoplasmic reticulum membrane localization || 1 0.31 0.43 0.41 0.38 0.37 0.09 0.28 0.41 0.65 0.22 -0.10 0.12 0.17 0.15 0.18 0.36
3326 || orf19.1441 || || || Ortholog of C. dubliniensis CD36 : Cd36_16230, C. parapsilosis CDC317 : CPAR2_213950, Candida tenuis NRRL Y-1498 : CANTEDRAFT_112720 and Debaryomyces hansenii CBS767 : DEHA2A01848g || 1 0.05 0.12 0.44 0.64 0.00 0.09 0.44 0.46 0.49 0.58 0.16 0.79 0.47 0.29 0.30 0.09
3327 || orf19.4243 || || || Ortholog(s) have ubiquitin binding activity || 1 0.27 0.38 0.14 0.28 -0.17 -0.25 0.21 0.42 0.11 0.56 0.12 0.34 0.34 0.44 0.36 0.28
3328 || orf19.7662 || || || Ortholog(s) have RNA polymerase II core binding activity, role in mRNA 3'-end processing, negative regulation of transposition, RNA-mediated and nuclear chromatin, site of double-strand break localization || 1 0.35 0.28 0.55 0.29 0.12 0.18 0.07 0.38 0.45 0.38 0.05 0.55 0.75 0.35 0.13 0.60
3329 || orf19.4394 || || || Protein of unknown function; induced by alpha pheromone in SpiderM medium || 1 0.59 0.45 0.43 0.23 0.20 0.13 0.04 0.70 0.13 0.18 0.09 0.74 0.50 -0.13 0.07 0.71
3330 || orf19.2433 || || || Ortholog of C. dubliniensis CD36 : Cd36_05790, C. parapsilosis CDC317 : CPAR2_103730, Pichia stipitis Pignal : PICST_28344, Candida tropicalis MYA-3404 : CTRG_04275 and Candida albicans WO-1 : CAWG_00795 || 1 0.73 0.73 0.26 0.17 -0.02 0.64 -0.19 0.54 -0.00 0.22 0.67 1.44 0.54 0.60 0.25 1.33
3331 || orf19.2081 || POM152 || || Putative nuclear pore membrane glycoprotein || 1 0.55 0.41 -0.06 0.33 0.15 0.22 0.42 0.59 -0.06 0.45 0.31 0.65 0.09 0.26 0.20 0.80
3332 || orf19.123 || RCN1 || || Protein involved in calcineurin-dependent signaling that controls stress response and virulence; inhibits calcineurin function || 1 0.36 0.39 0.18 0.20 0.01 0.19 0.46 0.35 -0.20 0.63 0.19 0.55 0.16 0.28 0.66 0.50
3333 || orf19.679 || FGR39 || || Protein lacking an ortholog in S. cerevisiae; transposon mutation affects filamentous growth || 1 0.45 0.24 0.13 0.03 -0.16 0.24 0.03 0.56 0.39 0.67 0.56 0.89 0.23 -0.02 0.57 0.38
3334 || orf19.469 || HST7 || || MAP kinase kinase involved in mating and hyphal growth signal transduction pathways; phosphorylates Cek1p; wild-type virulence in mouse systemic infection; functional homolog of S. cerevisiae Ste7p; mutants are hypersensitive to caspofungin || 1 0.16 0.06 0.55 0.50 -0.14 0.33 0.01 0.30 0.23 0.39 0.05 0.72 0.37 0.69 0.69 0.34
3335 || orf19.897 || VPS20 || || ESCRT III complex protein; role in multivesicular body (MVB) trafficking; required for processing of Rim8; Bcr1-repressed in RPMI a/a biofilms || 1 -0.26 -0.30 0.62 0.91 0.12 0.59 0.51 0.38 0.11 -0.11 0.11 1.07 0.40 0.50 1.40 0.87
3336 || orf19.474 || || || Ortholog(s) have role in mRNA export from nucleus, nuclear envelope organization, protein export from nucleus and endoplasmic reticulum, nuclear envelope localization || 1 -0.02 -0.09 0.58 0.48 0.13 0.03 0.29 0.04 0.04 -0.05 -0.09 0.68 0.21 0.25 0.31 0.45
3337 || orf19.3901 || || || Putative benzene desulfurase; induced by nitric oxide independent of Yhb1p || 1 0.31 -0.05 0.57 0.44 0.20 0.04 0.16 0.10 0.14 0.02 0.21 0.49 0.33 0.08 0.31 0.45
3338 || orf19.4924 || || || Protein of unknown function; repressed in ssr1 mutant; Spider biofilm induced || 1 0.66 0.47 0.57 0.38 -0.00 0.25 -0.11 0.12 0.02 0.09 -0.26 0.19 0.11 0.36 0.26 0.47
3339 || orf19.2630 || RAD59 || || Protein involved in homologous recombination and DNA breaks repair; similar to S. cerevisiae Rad59p; N-terminal similarity with Rad52p || 1 0.96 0.87 0.71 1.02 0.11 0.16 0.28 0.38 0.05 0.57 0.03 0.49 -0.06 0.60 0.68 0.70
3340 || orf19.4474 || || || Ortholog(s) have cytoplasm, nucleus localization || 1 1.18 0.88 0.81 0.75 0.22 0.31 0.18 0.43 0.17 0.15 0.31 0.55 -0.50 0.38 0.96 0.87
3341 || orf19.4011 || || || Similar to S. pombe mug180, a predicted esterase/lipase; highly induced during chlamydospore formation in both C. albicans and C. dubliniensis; flow model biofilm induced || 1 0.69 0.44 0.52 0.92 0.13 0.67 -0.08 0.59 0.23 0.40 -0.12 0.57 -0.28 0.30 0.40 0.18
3342 || orf19.135 || EXO84 || || Predicted subunit of the exocyst complex, involved in exocytosis; localizes to a crescent on the surface of the hyphal tip || 1 0.52 0.25 0.60 0.28 -0.09 0.28 0.12 0.12 0.52 -0.18 0.19 0.03 0.23 0.38 0.30 0.02
3343 || orf19.3907 || || || Ortholog of Candida albicans WO-1 : CAWG_04797 || 1 0.52 1.12 1.08 0.36 0.20 0.61 0.70 0.53 1.84 0.11 0.89 0.44 1.29 0.71 1.21 0.12
3344 || orf19.1011 || MNN21 || || Ortholog(s) have alpha-1,2-mannosyltransferase activity, role in cell wall mannoprotein biosynthetic process and Golgi apparatus localization || 1 0.36 0.20 0.61 0.60 0.30 0.27 0.87 0.70 0.90 -0.03 0.54 0.09 0.90 0.75 0.18 0.22
3345 || orf19.836.1 || || || Ortholog(s) have role in mRNA splicing, via spliceosome and U1 snRNP, U2 snRNP, U2-type prespliceosome, U4/U6 x U5 tri-snRNP complex, U5 snRNP, cytosol localization || 1 0.33 0.38 0.39 0.53 1.09 1.71 0.19 1.11 0.24 0.10 0.96 0.57 0.59 0.82 0.33 0.28
3346 || orf19.7620 || || || Ortholog(s) have role in mRNA splicing, via spliceosome and spliceosomal complex localization || 1 0.77 0.69 0.52 0.59 1.29 1.67 0.27 0.16 0.21 -0.53 1.89 0.29 1.38 0.83 -0.44 0.83
3347 || orf19.7444 || || || Ortholog(s) have cytoplasm, holo TFIIH complex localization || 1 0.47 0.37 0.21 0.10 0.83 0.68 0.63 0.10 0.05 0.06 1.14 0.41 0.57 0.25 0.26 0.52
3348 || orf19.3617 || GTR1 || || Putative GTP-binding protein; transcript is upregulated in clinical isolates from HIV+ patients with oral candidiasis; (see Locus History Note for Assembly 19 correction) || 1 0.62 0.66 0.46 -0.08 0.03 0.43 0.68 0.60 0.64 0.63 0.99 0.78 0.69 0.40 0.22 -0.28
3349 || orf19.3777 || IMG2 || || Mitochondrial ribosomal protein of the large subunit; rat catheter biofilm induced || 1 0.48 1.50 0.17 0.46 0.49 0.34 0.42 0.39 1.20 1.12 0.62 0.79 0.97 0.40 0.55 -0.12
3350 || orf19.7510 || KIN2 || || Protein with similarity to S. cerevisiae Kin2p, transcription is positively regulated by Tbf1 || 1 0.41 0.23 0.38 0.54 0.20 0.47 0.24 0.47 0.32 -0.10 -0.03 0.29 0.38 0.14 0.50 0.09
3351 || orf19.3202 || || || Ortholog of C. dubliniensis CD36 : Cd36_51590, C. parapsilosis CDC317 : CPAR2_303610, Candida tenuis NRRL Y-1498 : CANTEDRAFT_135127 and Debaryomyces hansenii CBS767 : DEHA2E19074g || 1 1.53 0.50 0.82 0.92 0.70 0.86 0.56 0.73 0.53 0.06 0.49 0.69 1.17 -0.32 0.75 0.05
3352 || orf19.1992 || SIR2 || || Required for wild-type lifespan, asymmetric inheritance of oxidatively damaged proteins, rDNA silencing; regulates phenotypic switch in strain 3153A, not WO-1; partially complements S. cerevisiae sir2 mating defect; Spider biofilm induced || 1 0.78 0.32 0.67 1.03 1.04 1.18 0.36 0.99 0.13 0.25 0.32 0.73 0.53 -0.24 -0.34 0.21
3353 || orf19.3998 || || || Ortholog(s) have Atg8 ligase activity, protein binding, bridging activity and role in C-terminal protein lipidation, CVT pathway, macroautophagy, mitochondrion degradation, piecemeal microautophagy of nucleus || 1 0.92 0.77 1.26 1.27 1.95 0.92 0.52 0.93 0.48 0.94 0.53 0.60 0.58 0.70 0.54 0.30
3354 || orf19.2299 || || || Ortholog(s) have protein tag activity and role in cell budding, cellular response to oxidative stress, invasive growth in response to glucose limitation, protein urmylation, tRNA wobble position uridine thiolation || 1 0.89 1.00 0.76 0.89 1.26 0.97 0.15 0.58 -0.36 0.59 0.68 0.57 0.04 0.22 -0.18 0.75
3355 || orf19.2299 || || || Ortholog(s) have protein tag activity and role in cell budding, cellular response to oxidative stress, invasive growth in response to glucose limitation, protein urmylation, tRNA wobble position uridine thiolation || 1 1.08 0.71 0.86 0.75 1.11 1.06 0.23 0.87 -0.04 0.80 0.38 0.47 0.15 0.26 0.10 0.56
3356 || orf19.2687.1 || || || Ortholog(s) have RNA polymerase I activity, RNA polymerase II activity, RNA polymerase III activity, RNA-directed RNA polymerase activity, zinc ion binding activity || 1 0.56 0.47 0.48 0.50 0.28 0.49 0.23 0.45 -0.17 0.39 0.37 0.20 0.25 0.27 -0.12 0.05
3357 || orf19.3255 || TEN1 || || Protein involved in telomere maintenance; forms a complex with Stn1; transcription is regulated upon yeast-hypha switch; Spider biofilm induced || 1 1.34 1.30 0.95 1.58 0.86 0.59 0.13 1.28 -0.10 0.89 0.34 0.39 1.05 0.19 0.17 0.12
3358 || orf19.5023 || DAL7 || || Putative allantoate permease; mutant is viable || 1 0.54 0.40 0.72 0.99 0.08 0.03 -0.10 0.57 0.36 0.20 0.16 0.53 0.18 0.22 0.21 0.52
3359 || orf19.5254 || || || Protein of unknown function; repressed by nitric oxide || 1 1.07 0.82 1.04 1.00 0.23 0.39 0.35 0.69 0.72 0.41 0.15 -0.00 0.13 0.84 -0.38 0.04
3360 || orf19.1871 || || || Ortholog(s) have structural molecule activity, role in histone exchange and Swr1 complex, cytosol localization || 1 0.40 0.25 0.46 0.42 0.05 0.20 0.07 0.22 0.36 0.10 -0.04 0.17 0.05 0.46 0.05 0.35
3361 || orf19.7578 || || || Ortholog(s) have oligosaccharide binding activity, role in ER-associated ubiquitin-dependent protein catabolic process and Hrd1p ubiquitin ligase ERAD-L complex, luminal surveillance complex localization || 1 0.66 0.67 0.64 0.50 0.02 0.34 0.43 0.70 0.53 0.35 -0.21 0.28 0.12 0.50 0.19 0.37
3362 || orf19.178 || || || Ortholog of C. dubliniensis CD36 : Cd36_32460, C. parapsilosis CDC317 : CPAR2_205480, Candida tenuis NRRL Y-1498 : CANTEDRAFT_115156 and Debaryomyces hansenii CBS767 : DEHA2E22154g || 1 0.89 0.96 0.55 0.56 0.03 0.01 -0.04 0.39 0.05 0.91 0.37 0.29 -0.17 0.08 0.38 0.34
3363 || orf19.1495 || || || Ortholog(s) have role in L-methionine salvage from methylthioadenosine and cytosol, nucleus localization || 1 1.43 1.65 0.85 1.07 0.31 0.46 0.33 0.56 0.22 0.55 0.42 0.34 0.04 0.48 -0.09 -0.06
3364 || orf19.1495 || || || Ortholog(s) have role in L-methionine salvage from methylthioadenosine and cytosol, nucleus localization || 1 1.53 1.55 0.96 1.35 0.43 0.50 0.36 0.64 0.27 0.63 0.55 0.54 0.01 0.45 -0.09 -0.08
3365 || orf19.1495 || || || Ortholog(s) have role in L-methionine salvage from methylthioadenosine and cytosol, nucleus localization || 1 1.59 1.58 0.93 1.41 0.49 0.63 0.39 0.73 0.27 0.71 0.47 0.65 0.09 0.71 -0.05 0.01
3366 || orf19.1495 || || || Ortholog(s) have role in L-methionine salvage from methylthioadenosine and cytosol, nucleus localization || 1 1.48 1.61 0.84 1.30 0.45 0.63 0.25 0.70 0.12 0.54 0.41 0.49 -0.06 0.61 -0.26 0.21
3367 || orf19.1495 || || || Ortholog(s) have role in L-methionine salvage from methylthioadenosine and cytosol, nucleus localization || 1 1.52 1.55 0.78 1.38 0.62 0.54 0.35 0.68 0.16 0.66 0.48 0.57 -0.11 0.62 0.28 0.14
3368 || orf19.4413 || CMD1 || || Calmodulin; calmodulin inhibitors cause a defect in hyphal growth; transcript not regulated by yeast-hyphal transition; mutation confers hypersensitivity to cytochalasin D and high concentrations of tunicamycin; gene has intron || 1 0.55 0.52 0.51 0.34 -0.05 0.07 -0.03 0.22 -0.11 0.06 0.42 0.32 -0.03 0.08 0.18 0.19
3369 || orf19.4726 || || || Ortholog(s) have calcium ion binding, enzyme activator activity || 1 0.78 0.31 0.38 0.46 -0.21 0.05 0.06 0.43 0.09 0.17 0.35 0.41 -0.16 0.01 0.29 0.36
3370 || orf19.2698 || || || Ortholog(s) have role in protein folding in endoplasmic reticulum and ER membrane protein complex localization || 1 0.71 0.60 1.17 1.15 -0.28 -0.13 0.36 0.87 0.29 0.50 0.53 0.61 0.05 0.54 0.30 0.24
3371 || orf19.6991 || PRE3 || || Putative beta-1 proteasome subunit; macrophage-induced protein; regulated by Gcn2p and Gcn4p; GlcNAc-induced protein || 1 0.76 0.86 0.81 0.86 0.30 0.16 0.20 0.56 0.24 0.36 0.51 0.55 0.12 0.26 0.56 0.10
3372 || orf19.5249 || || || Ortholog(s) have role in ascospore formation, meiosis and cytosol, nucleus localization || 1 1.17 0.98 0.93 0.97 0.05 -0.05 0.04 0.91 0.60 0.56 0.33 0.36 -0.06 0.38 0.67 -0.07
3373 || orf19.7178 || PRE5 || || Alpha6 subunit of the 20S proteasome; regulated by Gcn4; induced in response to amino acid starvation (3-AT); Spider biofilm repressed || 1 0.83 0.49 0.40 0.61 -0.18 0.03 0.47 0.43 0.25 0.47 0.47 0.32 0.06 0.05 0.39 0.06
3374 || orf19.6151 || ARC15 || || Putative ARP2/3 complex subunit; mutation confers hypersensitivity to cytochalasin D || 1 0.71 0.44 0.57 0.71 -0.14 -0.09 0.26 0.51 0.32 0.24 0.57 0.24 0.16 0.12 -0.04 -0.22
3375 || orf19.4205.1 || || || Ortholog(s) have role in mRNA splicing, via spliceosome and U1 snRNP, U2 snRNP, U2-type prespliceosome, U4/U6 x U5 tri-snRNP complex, U5 snRNP, cytosol localization || 1 0.63 0.84 0.64 0.45 0.00 0.31 0.40 0.77 0.44 0.73 0.88 0.27 0.30 0.07 0.00 -0.21
3376 || orf19.3976 || || || Ortholog(s) have structural constituent of cytoskeleton activity, role in establishment of mitotic spindle orientation, nuclear migration and astral microtubule, cell cortex, dynactin complex, spindle pole body localization || 1 0.65 0.81 0.50 0.54 0.60 0.63 0.42 0.64 0.04 0.81 0.77 0.10 0.26 -0.09 0.18 -0.24
3377 || orf19.2687.1 || || || Ortholog(s) have RNA polymerase I activity, RNA polymerase II activity, RNA polymerase III activity, RNA-directed RNA polymerase activity, zinc ion binding activity || 1 0.57 0.50 0.17 0.33 0.19 0.39 0.37 0.63 -0.31 0.43 0.65 0.08 0.13 -0.07 -0.14 -0.08
3378 || orf19.6551.1 || STE18 || || Protein similar to S. cerevisiae Ste18p; expressed in opaque or white MTLa/MTLa or MTLalpha/MTLalpha, but not MTLa/MTLalpha cells; MTLa1p, MTLalpha2p bind promoter region || 1 1.45 1.53 0.67 1.03 0.57 0.45 0.73 1.17 -0.21 0.35 1.03 0.24 -0.05 -0.02 -0.00 -0.20
3379 || orf19.592 || || || Ortholog of S. cerevisiae YNL092W and S. pombe SPBC1778.07; a putative N2227-like methyltransferase; Hap43-repressed gene || 1 0.44 0.54 0.97 1.29 0.77 0.14 0.60 0.80 0.36 -0.50 0.14 0.25 0.41 0.24 0.43 0.49
3380 || orf19.2862 || RIB1 || || Putative GTP cyclohydrolase II; enzyme of riboflavin biosynthesis; fungal-specific (no human or murine homolog); regulated by Sef1p-, Sfu1p-, and Hap43p || 1 0.78 0.41 0.95 0.86 0.40 0.21 0.66 0.78 0.76 -0.11 0.34 -0.12 0.39 0.50 0.21 0.02
3381 || orf19.2757 || || || Has domain(s) with predicted role in cell redox homeostasis || 1 0.55 0.44 1.39 0.88 0.41 0.44 0.61 0.77 0.60 -0.24 0.54 0.32 0.78 0.48 -0.24 0.37
3382 || orf19.5880 || || || Putative voltage-gated chloride channel; predicted role in copper ion and iron ion homeostasis; flow model biofilm induced || 1 0.31 0.41 1.48 0.86 0.33 0.12 0.28 0.62 0.47 -0.13 0.63 0.28 0.30 0.41 0.14 0.18
3383 || orf19.4730 || || || Ortholog of S. cerevisiae : YNL050C, C. glabrata CBS138 : CAGL0G01276g, C. dubliniensis CD36 : Cd36_08220, C. parapsilosis CDC317 : CPAR2_804440 and Candida tenuis NRRL Y-1498 : CANTEDRAFT_94168 || 1 0.35 0.49 0.84 0.81 0.45 0.23 0.28 0.72 0.01 -0.07 0.66 0.50 0.28 0.51 0.08 0.09
3384 || orf19.3359 || ARP8 || || Putative chromatin-remodeling enzyme complex protein; mutation confers hypersensitivity to toxic ergosterol analog, and to amphotericin B; rat catheter biofilm induced || 1 0.68 0.91 0.99 0.93 0.53 0.08 0.51 0.87 0.10 -0.19 0.99 0.18 0.55 0.61 0.22 0.33
3385 || orf19.3706 || || || Has domain(s) with predicted oxidoreductase activity, zinc ion binding activity and role in oxidation-reduction process || 1 0.84 1.34 0.95 1.23 0.76 0.04 0.15 0.24 0.33 0.18 0.65 0.25 0.35 0.23 0.25 0.22
3386 || orf19.6900 || || || Ortholog(s) have role in establishment or maintenance of cell polarity, mitochondrial genome maintenance, mitochondrion inheritance, phospholipid transport, protein import into mitochondrial outer membrane || 1 0.51 0.49 0.59 0.71 0.46 0.05 0.28 0.11 0.45 0.18 0.17 0.09 0.09 0.09 0.04 0.06
3387 || orf19.3963 || || || Ortholog(s) have mitochondrion localization || 1 0.57 0.72 1.06 1.19 0.51 -0.03 0.64 0.53 0.11 0.40 0.24 0.27 0.48 0.25 0.32 0.23
3388 || orf19.3371 || JAB1 || || Component of the COP9 signalosome (CSN) complex, provides catalytic activity for deneddylation that cleaves the ubiquitin-like protein tag Rub1p off the cullin (Cdc53p) molecule || 1 1.00 0.87 1.27 0.87 1.16 0.27 0.74 0.39 0.36 0.05 1.04 0.31 0.40 0.01 0.88 0.32
3389 || orf19.7480 || || || Putative protein of unknown function; transcript is upregulated in clinical isolates from HIV+ patients with oral candidiasis || 1 0.60 0.86 0.60 1.10 0.82 0.16 0.40 0.52 0.43 0.32 0.55 0.74 0.69 -0.12 0.61 1.02
3390 || orf19.787 || || || Protein of unknown function || 1 0.80 0.85 0.77 0.96 0.20 0.64 0.37 0.85 0.38 0.04 0.85 0.82 0.83 -0.14 0.50 0.49
3391 || orf19.811 || || || Protein of unknown function; mutant is viable; Hap43-repressed || 1 0.78 0.66 0.91 0.67 0.05 0.52 0.24 0.43 0.19 0.12 0.52 0.54 0.52 0.15 0.31 0.96
3392 || orf19.4699 || || || Putative phospholipase of patatin family; similar to S. cerevisiae Tgl3p; predicted Kex2p substrate || 1 1.02 0.99 0.74 0.87 0.27 0.06 0.19 0.38 0.21 0.10 0.60 0.40 0.69 0.15 0.06 0.76
3393 || orf19.4346 || || || Ortholog(s) have protein anchor activity, role in COPII vesicle coating, protein localization to endoplasmic reticulum exit site and ER to Golgi transport vesicle membrane, endoplasmic reticulum exit site localization || 1 0.37 0.44 0.48 0.51 0.33 -0.04 0.24 0.59 0.02 -0.04 0.67 -0.11 0.24 0.14 0.39 0.38
3394 || orf19.3148 || || || Protein of unknown function; possibly an essential gene, disruptants not obtained by UAU1 method || 1 0.74 0.64 0.46 0.49 0.59 -0.03 0.03 0.52 0.76 0.15 0.53 0.37 0.47 0.24 0.12 0.40
3395 || orf19.7589 || || || Protein of unknown function; Hap43-repressed gene; transcript induced by elevated CO2 || 1 0.86 0.83 1.32 1.23 0.04 0.11 0.82 0.97 0.63 0.62 0.85 -0.05 0.19 0.46 0.07 0.35
3396 || orf19.794 || SSN3 || || Putative cyclin-dependent protein kinase; mutants are sensitive to growth on H2O2 medium || 1 0.31 0.42 0.71 0.64 0.07 0.11 0.38 0.29 0.45 0.34 0.43 -0.18 0.22 0.10 -0.35 0.32
3397 || orf19.3639 || || || Ortholog(s) have alkylbase DNA N-glycosylase activity and role in DNA dealkylation involved in DNA repair, base-excision repair, AP site formation || 1 0.81 0.84 1.12 1.00 -0.41 0.12 0.28 0.12 0.42 0.71 0.74 0.51 1.42 0.97 0.29 0.36
3398 || orf19.6628 || || || Protein of unknown function; rat catheter biofilm repressed || 1 0.80 1.00 1.17 1.12 -0.05 -0.01 0.34 0.42 0.33 0.89 0.46 0.42 0.85 0.55 -0.25 0.33
3399 || orf19.2660 || EAF3 || || Subunit of the NuA4 histone acetyltransferase complex; rat catheter and Spider biofilm induced || 1 1.43 1.19 1.23 1.12 0.00 0.25 0.62 0.53 0.68 0.45 0.50 0.31 1.00 1.06 -0.08 0.26
3400 || orf19.5363 || || || Component of UDP-GlcNAc transferase; required for the 2nd step of dolichyl-linked oligosaccharide synthesis; Spider biofilm induced || 1 0.38 0.44 0.80 0.56 0.07 -0.04 0.11 0.30 0.34 0.09 -0.14 0.17 0.23 0.27 0.15 0.02
3401 || orf19.3042 || || || Protein of unknown function; Hap43-induced; rat catheter biofilm induced || 1 0.29 0.22 0.78 0.83 -0.14 -0.12 -0.09 0.11 0.33 0.35 0.05 0.59 0.37 0.52 0.17 -0.22
3402 || orf19.6858 || EDC3 || || Ortholog(s) have role in cytoplasmic mRNA processing body assembly, deadenylation-independent decapping of nuclear-transcribed mRNA and cytoplasmic mRNA processing body localization || 1 0.38 0.51 0.93 0.69 -0.12 0.03 0.15 0.22 0.34 0.34 0.16 0.58 0.34 0.12 0.22 0.12
3403 || orf19.2940 || || || Putative v-SNARE of the endoplasmic reticulum membrane; possibly an essential gene, disruptants not obtained by UAU1 method || 1 0.53 0.72 1.59 1.24 0.34 0.14 0.36 0.43 0.75 0.63 0.52 0.52 0.62 0.52 0.19 0.12
3404 || orf19.927 || || || Ortholog(s) have role in positive regulation of transcription from RNA polymerase II promoter, telomere maintenance and EKC/KEOPS complex, cytosol, nucleus localization || 1 0.55 0.31 0.90 0.75 0.25 -0.11 0.36 0.48 0.38 0.58 0.40 0.63 0.56 0.55 0.48 -0.06
3405 || orf19.6129 || MRPL8 || || Mitochondrial 60S ribosomal protein subunit; Hap43p-repressed gene || 1 0.08 0.45 1.07 0.75 0.31 -0.03 0.44 0.33 0.65 0.75 0.29 0.90 0.53 0.23 0.42 -0.35
3406 || orf19.3605 || PEX17 || || Putative peroxin || 1 0.48 0.52 0.28 0.50 0.66 0.30 0.17 0.68 0.52 -0.31 0.71 0.45 0.59 0.40 0.85 0.01
3407 || orf19.3286 || || || Ortholog(s) have alpha-glucosidase activity, role in polysaccharide biosynthetic process, protein N-linked glycosylation and endoplasmic reticulum lumen, glucosidase II complex localization || 1 0.80 0.42 -0.09 -0.01 0.90 0.48 0.59 0.45 1.00 0.48 0.69 0.34 0.39 0.82 0.58 0.22
3408 || orf19.5254 || || || Protein of unknown function; repressed by nitric oxide || 1 0.75 1.03 0.33 0.31 1.53 0.10 0.70 0.63 -0.10 0.59 1.16 0.15 0.80 1.12 0.06 0.32
3409 || orf19.4677 || || || Putative protein of unknown function, transcript is upregulated in clinical isolates from HIV+ patients with oral candidiasis; Spider biofilm induced || 1 0.49 0.69 0.40 0.33 1.09 0.36 0.30 0.51 0.20 0.45 0.69 0.24 0.37 0.89 0.46 -0.08
3410 || orf19.2305 || || || Ortholog(s) have tubulin binding activity, role in tubulin complex assembly and prefoldin complex localization || 1 0.45 0.49 1.30 1.24 0.56 0.85 0.16 0.51 1.16 1.15 0.32 0.71 0.82 0.94 -0.14 0.51
3411 || orf19.5666 || || || Ortholog(s) have transcription coactivator activity || 1 0.56 0.79 1.13 0.63 0.20 0.74 0.83 0.86 1.21 1.20 0.69 0.69 0.51 1.03 -0.19 0.92
3412 || orf19.3963 || || || Ortholog(s) have mitochondrion localization || 1 0.25 0.52 0.78 0.62 0.05 0.38 0.20 0.19 0.69 0.87 0.46 0.37 0.32 0.74 0.14 0.62
3413 || orf19.5875 || VAM3 || || Predicted target membrane receptor (t-SNARE) involved in vacuolar transport, endocytosis, and secretion; required for biofilm formation in RPMI-1640 and for virulence; rat catheter biofilm repressed || 1 0.33 0.61 0.95 0.75 0.36 0.48 0.42 0.58 1.11 1.33 1.03 0.55 0.58 1.13 0.28 0.54
3414 || orf19.5486.1 || SMD2 || || Putative Core Sm protein; Hap43p-induced gene; flucytosine induced || 1 1.07 1.08 1.09 0.92 0.71 0.86 0.08 0.90 1.13 1.74 1.01 1.28 0.37 0.94 0.38 0.73
3415 || orf19.4594 || CLC1 || || Clathrin light chain; subunit of the major coat protein involved in intracellular protein transport and endocytosis; rat cathetr and Spider biofilm repressed || 1 0.59 0.74 1.09 0.78 0.50 0.70 0.19 0.79 1.01 1.07 1.16 1.04 0.85 0.75 0.47 0.67
3416 || orf19.7509.2 || LSM6 || || Putative Lsm protein; flucytosine induced || 1 0.25 0.59 1.03 0.84 0.78 0.86 0.49 0.99 1.04 0.83 0.99 0.73 0.31 0.86 0.09 0.41
3417 || orf19.7509.2 || LSM6 || || Putative Lsm protein; flucytosine induced || 1 0.48 0.94 1.39 1.09 0.45 1.15 0.86 1.19 0.96 0.90 0.74 0.88 0.55 1.13 0.62 0.85
3418 || orf19.7509.2 || LSM6 || || Putative Lsm protein; flucytosine induced || 1 0.70 0.71 1.01 1.11 0.55 1.21 0.71 1.27 0.91 1.02 0.86 0.92 0.71 1.06 0.53 0.56
3419 || orf19.7509.2 || LSM6 || || Putative Lsm protein; flucytosine induced || 1 0.54 0.93 0.99 0.93 0.34 1.11 0.66 1.01 1.22 1.03 1.15 0.67 0.60 0.89 0.18 0.65
3420 || orf19.7509.2 || LSM6 || || Putative Lsm protein; flucytosine induced || 1 1.25 0.84 0.88 1.31 0.45 1.12 0.52 1.08 1.19 0.90 0.96 0.88 0.61 1.12 0.25 0.66
3421 || orf19.643 || || || Ortholog(s) have role in apoptotic process, mitotic spindle elongation, sister chromatid biorientation, spindle assembly checkpoint || 1 0.31 0.70 0.79 0.86 0.96 0.29 0.46 0.74 1.02 0.88 0.98 0.93 0.82 1.26 0.44 0.43
3422 || orf19.3687 || || || Ortholog(s) have unfolded protein binding activity, role in cytoskeleton organization, protein folding and prefoldin complex localization || 1 0.16 0.42 0.54 0.83 0.58 0.34 0.23 0.79 1.03 1.33 0.63 0.94 0.49 1.02 0.31 0.57
3423 || orf19.7139 || || || Ortholog(s) have role in mRNA splicing, via spliceosome || 1 0.38 0.43 0.75 0.88 0.72 1.31 0.96 0.97 1.46 1.49 0.75 0.92 0.60 1.82 0.38 0.76
3424 || orf19.7139 || || || Ortholog(s) have role in mRNA splicing, via spliceosome || 1 1.05 1.49 1.10 1.27 0.69 1.26 1.19 1.34 1.85 1.76 0.62 0.74 1.61 2.00 0.37 0.19
3425 || orf19.187 || || || Predicted ORF in Assemblies 19, 20 and 21; merged with orf19.188 in Assembly 21 || 1 0.63 1.12 1.03 0.08 1.74 2.06 0.84 0.97 1.29 1.78 1.41 0.88 1.25 1.11 1.00 1.31
3426 || orf19.1483 || || || Ortholog(s) have copper ion binding activity, role in mitochondrial respiratory chain complex IV assembly and extrinsic to mitochondrial inner membrane, mitochondrial intermembrane space localization || 1 0.20 0.72 0.95 0.31 0.85 1.41 0.21 0.47 0.91 1.04 0.60 0.88 0.57 0.53 0.49 0.88
3427 || orf19.639 || || || S. cerevisiae ortholog YDR370C/DXO1 has decapping and 5′-3′ exoRNase activity; decreased transcription is observed upon fluphenazine treatment or in an azole-resistant strain that overexpresses CDR1 and CDR2 || 1 0.27 0.38 1.06 0.82 1.06 1.25 0.49 0.83 0.73 0.24 0.62 0.50 0.50 0.86 0.33 0.65
3428 || orf19.6563 || KCH1 || || Ortholog of Kch1 a potassium transporter; mediates K+ influx and activates high-affinity Ca2+ influx system during mating pheromone response in S. cerevisiae; induced by alpha pheromone in SpiderM medium || 1 0.80 0.48 0.89 0.55 1.05 0.90 0.85 0.17 0.26 0.64 0.55 0.45 0.39 1.23 0.60 0.42
3429 || orf19.6360 || || || Protein involved in pre-mRNA splicing; Spider biofilm induced || 1 0.87 0.92 1.00 0.91 1.12 1.95 0.13 0.10 0.70 0.98 0.64 1.51 0.79 1.50 0.60 1.16
3430 || orf19.6685 || ISY1 || || Putative pre-mRNA-splicing factor; mutation confers resistance to 5-fluorocytosine (5-FC); rat catheter biofilm induced || 1 0.64 0.66 0.95 1.05 1.39 1.60 0.46 0.33 0.46 0.73 0.48 0.69 0.43 0.98 0.55 0.96
3431 || orf19.3530 || CKA2 || || Catalytic alpha-subunit of protein kinase CK2; interaction with calcineurin pathway affects fluconazole sensitivity; synthetically lethal with CKA1; attenuated virulence in a mouse oropharyngeal candidiasis but not in a systemic mouse model || 1 0.43 0.57 0.53 0.39 0.42 0.51 0.47 0.24 0.21 0.27 0.33 0.38 0.21 0.43 0.10 0.15
3432 || orf19.998 || || || Putative adapter protein; links synaptojanins Inp52 and Inp53 to the cortical actin cytoskeleton in S. cerevisiae; mutants are viable || 1 0.74 0.84 1.13 0.98 0.77 1.08 0.64 0.31 0.78 0.65 0.82 0.86 0.96 0.94 0.65 0.45
3433 || orf19.7343 || || || Ortholog(s) have role in mRNA splicing, via spliceosome and U4/U6 x U5 tri-snRNP complex localization || 1 0.32 0.42 0.57 0.45 0.28 0.62 0.19 0.10 0.23 0.18 0.44 0.50 0.62 0.27 0.26 0.26
3434 || orf19.469 || HST7 || || MAP kinase kinase involved in mating and hyphal growth signal transduction pathways; phosphorylates Cek1p; wild-type virulence in mouse systemic infection; functional homolog of S. cerevisiae Ste7p; mutants are hypersensitive to caspofungin || 1 0.57 0.47 0.94 0.76 0.03 0.68 0.65 0.46 0.68 0.34 0.62 1.06 0.76 1.28 1.10 0.82
3435 || orf19.537 || || || Ortholog of C. dubliniensis CD36 : Cd36_29810, C. parapsilosis CDC317 : CPAR2_206030, Candida tenuis NRRL Y-1498 : CANTEDRAFT_102086 and Debaryomyces hansenii CBS767 : DEHA2F14014g || 1 0.34 0.45 0.86 0.77 0.71 0.86 0.59 0.60 0.47 0.64 1.15 1.00 0.56 0.92 1.06 0.97
3436 || orf19.6742 || || || Ortholog(s) have CTD phosphatase activity || 1 0.70 0.74 0.82 1.34 0.37 0.80 0.42 1.06 0.33 0.69 0.79 0.93 1.02 0.66 0.83 0.52
3437 || orf19.4046 || || || Putative transcription factor containing a Zn(2)-Cys(6) binuclear cluster || 1 0.64 0.62 0.51 0.80 -0.04 0.39 0.64 0.68 0.33 0.65 0.49 0.57 0.46 0.52 0.69 0.93
3438 || orf19.3421.1 || MED19 || || RNA polymerase II mediator complex subunit || 1 1.07 0.43 1.41 1.23 0.40 0.40 0.74 0.84 0.51 1.00 0.56 0.48 0.34 0.43 0.95 0.93
3439 || orf19.2708 || || || Ortholog(s) have guanyl-nucleotide exchange factor activity, role in mature ribosome assembly and cytosol, nucleolus, polysome, preribosome, large subunit precursor localization || 1 0.70 0.34 0.65 0.68 0.56 0.94 0.18 0.56 0.43 0.51 0.36 0.81 0.09 0.31 0.52 0.42
3440 || orf19.6166 || || || Ortholog of C. dubliniensis CD36 : Cd36_80810, C. parapsilosis CDC317 : CPAR2_101800, Candida tenuis NRRL Y-1498 : CANTEDRAFT_103482 and Debaryomyces hansenii CBS767 : DEHA2F17864g || 1 0.63 0.45 0.24 1.16 0.81 1.10 0.05 1.00 0.53 0.73 0.52 0.90 0.22 0.35 0.54 0.09
3441 || orf19.4983 || || || Ortholog of C. dubliniensis CD36 : Cd36_12520, C. parapsilosis CDC317 : CPAR2_201720, Candida tenuis NRRL Y-1498 : CANTEDRAFT_108003 and Debaryomyces hansenii CBS767 : DEHA2D05214g || 1 0.25 0.24 0.33 0.36 0.38 0.49 0.10 0.43 0.44 0.33 0.29 0.16 0.13 0.16 0.21 -0.01
3442 || orf19.7444 || || || Ortholog(s) have cytoplasm, holo TFIIH complex localization || 1 0.53 0.29 0.24 0.02 0.52 0.65 0.66 0.38 0.73 -0.08 1.17 0.44 0.23 0.54 0.11 0.54
3443 || orf19.674 || || || Ortholog(s) have U6 snRNA binding, pre-mRNA binding activity and role in mRNA cis splicing, via spliceosome, spliceosomal snRNP assembly || 1 0.50 0.25 0.37 -0.20 0.55 0.97 0.92 0.69 0.51 0.19 1.74 1.16 0.57 0.43 0.56 0.44
3444 || orf19.2965.1 || || || Protein of unknown function; similar to human SERF2; gene has an alternatively spliced intron || 1 0.23 0.46 0.54 0.09 0.59 1.18 0.81 0.83 0.88 0.39 1.18 0.92 0.80 0.51 0.54 0.95
3445 || orf19.2708 || || || Ortholog(s) have guanyl-nucleotide exchange factor activity, role in mature ribosome assembly and cytosol, nucleolus, polysome, preribosome, large subunit precursor localization || 1 0.24 0.85 0.27 0.24 0.38 1.32 0.78 0.79 0.73 0.89 1.12 0.61 0.24 0.59 0.85 0.64
3446 || orf19.4983 || || || Ortholog of C. dubliniensis CD36 : Cd36_12520, C. parapsilosis CDC317 : CPAR2_201720, Candida tenuis NRRL Y-1498 : CANTEDRAFT_108003 and Debaryomyces hansenii CBS767 : DEHA2D05214g || 1 0.36 0.50 0.10 -0.22 0.54 0.85 0.92 0.68 0.81 0.49 0.83 0.83 -0.10 0.43 0.52 0.71
3447 || orf19.3763 || || || Has domain(s) with predicted serine-type endopeptidase activity and integral to membrane localization || 1 0.20 0.31 0.34 0.19 0.23 -0.07 0.72 0.72 0.43 0.28 0.57 0.78 0.50 0.05 0.51 0.46
3448 || orf19.520 || || || Ortholog of C. dubliniensis CD36 : Cd36_29660, C. parapsilosis CDC317 : CPAR2_205200, Candida tenuis NRRL Y-1498 : CANTEDRAFT_96118 and Debaryomyces hansenii CBS767 : DEHA2F21428g || 1 0.33 0.35 0.44 0.19 0.23 0.09 0.59 0.23 0.56 0.09 0.58 0.28 0.47 0.20 0.58 0.32
3449 || orf19.6246 || || || Ortholog(s) have peptide alpha-N-acetyltransferase activity, role in N-terminal peptidyl-methionine acetylation, cytoskeleton organization, mitochondrion inheritance and NatB complex, cytosol, nucleus localization || 1 0.67 0.51 0.70 0.47 0.29 0.19 0.89 0.59 0.56 -0.14 1.13 0.63 0.70 0.87 0.68 0.81
3450 || orf19.7163 || || || Ortholog of C. dubliniensis CD36 : Cd36_73790, C. parapsilosis CDC317 : CPAR2_702880, Candida tenuis NRRL Y-1498 : CANTEDRAFT_92070 and Debaryomyces hansenii CBS767 : DEHA2D10318g || 1 0.88 0.85 0.94 0.84 0.39 0.86 0.63 0.89 0.14 0.29 1.50 1.04 0.69 0.51 0.68 1.51
3451 || orf19.7163 || || || Ortholog of C. dubliniensis CD36 : Cd36_73790, C. parapsilosis CDC317 : CPAR2_702880, Candida tenuis NRRL Y-1498 : CANTEDRAFT_92070 and Debaryomyces hansenii CBS767 : DEHA2D10318g || 1 1.31 1.15 0.83 0.69 0.33 0.69 0.49 1.24 0.09 0.47 2.01 1.05 0.65 0.78 0.86 1.57
3452 || orf19.1136 || || || Ortholog(s) have AP-2 adaptor complex, cytosol, nucleus localization || 1 0.62 0.74 0.42 0.47 0.25 -0.05 0.24 0.56 0.39 0.21 0.78 0.61 0.26 0.19 0.44 0.91
3453 || orf19.5221 || || || Ortholog(s) have phosphatidylinositol-4,5-bisphosphate binding activity || 1 0.43 0.50 0.31 0.25 0.11 0.08 0.19 0.61 0.35 0.15 0.58 0.53 0.52 0.44 0.47 0.78
3454 || orf19.3054 || RPN3 || || Putative non-ATPase regulatory subunit of the 26S proteasome lid; amphotericin B repressed; oxidative stress-induced via Cap1p || 1 0.44 0.41 0.22 0.28 0.04 0.01 0.44 0.67 0.12 0.25 0.52 0.54 0.14 0.44 0.60 0.90
3455 || orf19.1500 || || || Ortholog of C. dubliniensis CD36 : Cd36_16720, C. parapsilosis CDC317 : CPAR2_210210, Candida tenuis NRRL Y-1498 : CANTEDRAFT_128446 and Debaryomyces hansenii CBS767 : DEHA2B04092g || 1 0.59 0.53 0.66 0.34 0.12 0.22 0.79 0.92 0.42 0.24 1.03 0.71 0.30 0.46 1.05 0.93
3456 || orf19.4615 || || || Ortholog(s) have histone deacetylase activity || 1 0.43 0.35 0.52 0.41 0.23 0.10 0.49 0.58 0.38 0.29 0.92 1.08 0.40 0.29 0.65 0.74
3457 || orf19.6804 || || || Ortholog(s) have signal sequence binding activity, role in protein targeting to ER and cytosol, nuclear periphery, signal recognition particle, endoplasmic reticulum targeting localization || 1 0.56 0.50 0.41 0.04 0.64 0.06 0.47 1.00 0.23 0.54 1.15 1.22 0.36 0.18 0.58 1.11
3458 || orf19.4164 || || || Ortholog(s) have mitochondrion, ribosome localization || 1 0.44 0.51 0.19 0.05 0.43 0.23 0.49 0.85 0.14 0.66 0.86 1.00 0.52 0.43 0.84 0.87
3459 || orf19.2055 || NPL6 || || Putative nuclear protein localization factor; Hap43-induced; Spider biofilm repressed || 1 0.92 0.90 0.18 0.54 0.60 0.29 0.62 0.88 0.20 0.59 1.53 1.18 0.83 -0.04 1.17 0.83
3460 || orf19.3248 || || || Ortholog of C. dubliniensis CD36 : Cd36_26070, C. parapsilosis CDC317 : CPAR2_803220, Candida tenuis NRRL Y-1498 : CANTEDRAFT_131795 and Debaryomyces hansenii CBS767 : DEHA2E12694g || 1 0.57 0.94 0.31 0.47 0.42 0.11 0.93 1.42 -0.02 -0.06 1.65 1.19 1.19 0.30 1.23 0.87
3461 || orf19.5196 || ESS1 || || Prolyl isomerase (parvulin class); essential; involved in yeast-hyphal switching, Cph1p pathway; has inflexible linker between WW and isomerase domains, unlike human homolog; functional homolog of S. cerevisiae Ess1p || 1 0.41 0.40 0.17 0.12 -0.12 0.22 0.82 0.79 0.15 0.14 1.31 0.90 0.33 0.26 0.54 0.66
3462 || orf19.2519 || || || Ortholog(s) have role in chromosome segregation and nuclear MIS12/MIND complex localization || 1 0.18 0.12 0.37 0.17 0.15 -0.06 0.50 0.63 0.09 0.06 1.24 0.71 0.72 0.50 0.42 0.64
3463 || orf19.2639.1 || || || Lsm (Like Sm) protein; predicted role in involved in mRNA decay; Spider biofilm repressed || 1 0.33 0.22 0.30 0.39 0.51 0.50 0.17 0.91 0.29 0.36 1.83 1.20 0.62 0.75 0.58 0.99
3464 || orf19.3116 || EXM2 || || Putative U1 snRNP complex compotent; decreased transcription is observed upon fluphenazine treatment || 1 0.46 0.45 0.27 0.44 0.45 0.60 0.24 0.38 0.71 0.40 0.66 0.47 0.21 0.41 0.42 0.20
3465 || orf19.5486.1 || SMD2 || || Putative Core Sm protein; Hap43p-induced gene; flucytosine induced || 1 1.31 1.21 0.32 1.47 0.85 0.94 1.10 1.25 1.30 2.04 2.09 1.69 0.86 0.79 0.94 0.40
3466 || orf19.5035 || HPC2 || || Ortholog(s) have DNA binding, nucleosome binding activity || 1 0.86 0.65 -0.18 0.52 0.57 1.05 0.75 1.49 1.02 1.74 1.87 1.11 0.48 0.44 0.61 1.11
3467 || orf19.2828 || || || Ortholog(s) have alpha-tubulin binding, microtubule binding activity, role in establishment or maintenance of cell polarity, post-chaperonin tubulin folding pathway and cytosol, nucleus localization || 1 0.07 0.19 -0.04 0.11 0.11 0.05 0.34 0.47 0.51 0.30 0.45 0.59 0.12 0.41 0.05 0.13
3468 || orf19.3533 || || || Ortholog(s) have role in ascospore formation, mitochondrial respiratory chain complex assembly, positive regulation of transcription from RNA polymerase II promoter || 1 0.38 1.16 -0.28 0.15 0.46 -0.25 1.58 1.89 1.11 1.61 1.67 1.01 0.25 1.30 0.64 0.64
3469 || orf19.7109 || || || Ortholog(s) have role in meiosis and cytosol, nucleus localization || 1 0.40 0.44 -0.06 0.08 0.11 0.06 0.50 0.56 0.34 0.37 0.29 0.60 -0.20 0.46 0.54 0.44
3470 || orf19.6040 || SNF7 || || ESCRT III complex protein; role in proteolytic activation of Rim101 and Rim8 processing/activation; separable roles in RIM101 pathway and in transport from MVB to vacuole; involved in echinocandin and azole sensitivity || 1 0.57 0.58 0.07 -0.02 0.20 0.06 0.47 0.56 0.50 0.58 0.36 0.59 0.15 0.70 0.31 0.60
3471 || orf19.6585 || || || Ortholog(s) have mitochondrion localization || 1 0.98 0.98 0.57 0.39 0.54 0.30 0.68 0.96 0.92 1.05 0.54 0.91 0.40 0.60 0.49 0.33
3472 || orf19.1934 || HST3 || || Histone H3K56 deacetylase; reduced copy number increases opaque cell formation; repressed by MMS, hydroxyurea and high-levels of hydrogen peroxide; Hap43p-induced; ectopic expression blocks genotoxin-induced switching; nicotinamide target || 1 0.67 0.43 0.35 0.30 0.18 -0.03 1.00 0.98 0.64 1.01 0.54 1.07 0.25 0.54 0.67 0.42
3473 || orf19.2828 || || || Ortholog(s) have alpha-tubulin binding, microtubule binding activity, role in establishment or maintenance of cell polarity, post-chaperonin tubulin folding pathway and cytosol, nucleus localization || 1 0.24 0.44 0.53 0.53 0.28 -0.20 0.39 0.58 0.53 0.49 0.41 0.51 0.38 0.32 0.19 0.31
3474 || orf19.3788 || SPC34 || || Subunit of the Dam1 (DASH) complex, which acts in chromosome segregation by coupling kinetochores to spindle microtubules || 1 0.44 0.49 0.63 0.68 0.51 0.04 0.65 0.78 0.90 0.96 0.87 0.76 0.87 0.59 0.33 0.90
3475 || orf19.1273 || || || Ortholog(s) have tubulin binding activity, role in tubulin complex assembly and prefoldin complex localization || 1 0.61 0.77 0.66 0.75 0.25 0.14 0.74 1.09 0.84 1.16 1.30 1.12 1.17 1.04 0.91 0.69
3476 || orf19.5568 || VPS51 || || Protein with a role in vacuolar function; null mutant has defect in damaging oral epithelial and vascular endothelial cells; required for normal hyphal growth and stress resistance; induced in presence of host oral or vascular cells || 1 0.46 0.81 0.16 0.18 0.15 0.05 0.62 0.49 0.57 0.34 1.19 0.62 0.62 0.89 0.42 0.60
3477 || orf19.1941 || NUF2 || || Kinetochore component; amount of Nuf2p and Mtw1p protein detected at each centromere is consistent with a single kinetochore microtubule attachment site || 1 0.47 1.07 0.15 0.12 0.46 -0.59 0.90 0.89 1.09 1.16 1.46 0.88 0.65 1.41 1.05 0.81
3478 || orf19.945 || VPS2 || || Ortholog(s) have role in intralumenal vesicle formation, protein retention in Golgi apparatus, protein targeting to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway || 1 0.54 0.60 0.39 0.31 0.33 -0.20 0.69 0.85 0.74 0.38 0.71 0.56 0.46 0.99 0.84 0.30
3479 || orf19.6537 || || || Ortholog(s) have role in chromosome segregation and nuclear MIS12/MIND complex, spindle pole localization || 1 0.56 0.24 -0.02 0.44 0.83 0.19 0.57 1.10 0.46 0.72 0.91 0.83 0.81 1.16 0.80 1.17
3480 || orf19.5325 || KIN3 || || Protein similar to S. cerevisiae Kin3p; induced under Cdc5p depletion; shows Mob2p-dependent hyphal regulation; mutants are hypersensitive to caspofungin || 1 0.38 0.38 0.23 0.64 -0.03 0.41 0.48 0.83 0.26 0.64 0.83 0.73 0.65 1.07 0.27 0.82
3481 || orf19.4324 || || || Has domain(s) with predicted NADH dehydrogenase (ubiquinone) activity, electron carrier activity and membrane localization || 1 0.44 0.63 0.24 0.75 0.14 0.94 0.41 0.88 0.97 1.18 0.98 1.12 0.49 1.19 0.83 1.06
3482 || orf19.5325 || KIN3 || || Protein similar to S. cerevisiae Kin3p; induced under Cdc5p depletion; shows Mob2p-dependent hyphal regulation; mutants are hypersensitive to caspofungin || 1 0.52 0.48 0.35 0.68 0.16 0.69 0.74 1.22 0.77 0.94 0.93 1.08 0.23 1.34 0.76 1.17
3483 || orf19.2442 || || || Ortholog of S. cerevisiae Shg1; a COMPASS (Set1C) complex subunit that methylates histone H3 on lysine 4 and is required in transcriptional silencing near telomeres; repressed in an azole-resistant strain overexpressing MDR1 || 1 0.65 0.99 0.14 0.27 0.79 1.04 0.71 1.28 0.80 0.90 1.43 1.29 0.20 1.35 1.26 1.21
3484 || orf19.2609 || CET1 || || mRNA 5'-triphosphatase; large subunit of mRNA capping enzyme; positively regulates Ceg1 activity; functional homolog of S. cerevisiae Cet1; Cet1 and Cgt1 form a 2:1 complex; flow model biofilm induced || 1 -0.03 -0.04 0.17 0.06 0.48 0.27 0.49 0.59 0.47 0.56 0.82 0.39 0.24 0.44 0.55 0.61
3485 || orf19.7116 || || || Protein of unknown function; transcript induced in RHE model of oral candidiasis; Spider biofilm repressed || 1 0.30 0.43 0.19 0.14 0.26 0.24 0.57 1.01 0.54 0.74 1.53 0.93 0.33 1.18 0.57 0.80
3486 || orf19.4388 || || || Protein with a histone fold domain; similar to TAFII47 proteins from S. cerevisiae, Danio rerio, Drosophila melanogaster, human, and mouse || 1 0.16 0.16 0.45 0.10 0.08 0.31 0.61 0.64 0.73 0.71 1.17 0.65 0.21 0.88 0.58 0.59
3487 || orf19.1934 || HST3 || || Histone H3K56 deacetylase; reduced copy number increases opaque cell formation; repressed by MMS, hydroxyurea and high-levels of hydrogen peroxide; Hap43p-induced; ectopic expression blocks genotoxin-induced switching; nicotinamide target || 1 0.57 0.53 0.12 0.31 0.32 0.19 0.79 0.87 1.06 1.35 1.02 1.02 0.72 0.80 0.44 0.21
3488 || orf19.5433 || || || Ortholog(s) have protein binding involved in protein folding activity, role in mitochondrial respiratory chain complex III assembly and mitochondrial matrix localization || 1 -0.07 0.51 -0.14 -0.01 0.34 0.30 0.78 1.17 1.54 1.24 1.45 1.20 1.01 0.72 0.79 0.79
3489 || orf19.7409.1 || || || Ortholog(s) have structural constituent of ribosome activity and mitochondrial large ribosomal subunit localization || 1 1.17 0.69 0.06 0.25 0.95 0.84 1.75 3.28 2.51 2.57 2.38 2.11 1.57 1.86 2.19 1.33
3490 || orf19.7409.1 || || || Ortholog(s) have structural constituent of ribosome activity and mitochondrial large ribosomal subunit localization || 1 0.25 0.40 0.50 -0.05 1.07 0.65 1.47 2.08 1.79 2.43 2.19 1.72 1.22 1.70 1.34 0.72
3491 || orf19.7067 || || || Ortholog(s) have RNA polymerase II core binding, RNA polymerase II transcription factor binding transcription factor activity, triplex DNA binding activity || 1 0.25 0.38 0.39 0.43 0.48 0.46 0.81 1.14 1.08 1.21 1.26 1.24 0.80 1.13 0.74 1.08
3492 || orf19.2520 || || || Ortholog(s) have structural constituent of ribosome activity and mitochondrial small ribosomal subunit localization || 1 0.26 0.15 -0.04 0.42 0.77 0.47 1.14 1.40 0.81 1.35 1.52 1.39 1.04 0.72 1.54 0.67
3493 || orf19.7067 || || || Ortholog(s) have RNA polymerase II core binding, RNA polymerase II transcription factor binding transcription factor activity, triplex DNA binding activity || 1 0.25 0.15 -0.39 -0.13 0.40 0.26 1.15 1.28 1.15 1.24 1.71 1.34 0.58 1.46 0.73 1.34
3494 || orf19.325 || || || Putative mRNA cleavage and polyadenlylation factor; heterozygous null mutant exhibits hypersensitivity to parnafungin and cordycepin in the C. albicans fitness test || 1 0.11 0.09 -0.16 -0.04 0.29 0.28 0.63 0.72 0.60 0.64 0.97 0.99 0.87 0.79 0.75 0.77
3495 || orf19.4284 || BUR2 || || Protein with similarity to S. cerevisiae Bur2p, contains a cyclin domain; not required for wild-type hyphal growth, adherence to buccal epithelial cells, or virulence in mouse systemic infection || 1 -0.06 0.25 -0.69 0.02 0.30 0.56 0.84 0.82 0.80 1.11 0.99 1.07 0.95 1.21 0.53 0.94
3496 || orf19.5269 || || || Ortholog of C. dubliniensis CD36 : Cd36_11210, C. parapsilosis CDC317 : CPAR2_805180, Candida tenuis NRRL Y-1498 : CANTEDRAFT_116279 and Debaryomyces hansenii CBS767 : DEHA2B10714g || 1 0.13 0.14 -0.01 -0.27 0.24 -0.19 0.59 0.68 0.71 0.65 0.75 0.59 0.79 0.69 0.45 0.58
3497 || orf19.4340.1 || || || Ortholog(s) have role in mRNA splicing, via spliceosome and U1 snRNP, U2 snRNP, U4/U6 x U5 tri-snRNP complex, U5 snRNP, cytosol localization || 1 0.57 0.26 0.29 0.10 0.09 0.50 0.75 0.52 0.98 1.35 0.70 0.84 0.81 1.21 0.74 0.63
3498 || orf19.132 || || || Ortholog(s) have role in histone deacetylation, negative regulation of chromatin silencing at telomere, negative regulation of meiosis, positive regulation of stress-activated MAPK cascade || 1 0.12 0.53 0.51 -0.08 0.22 0.37 0.68 0.76 0.95 0.74 0.69 0.59 0.67 0.69 0.42 0.88
3499 || orf19.7023 || || || Ortholog of S. cerevisiae Ioc4, a protein that influences gene expression through chromatin remodeling; oxidative stress-induced via Cap1 || 1 0.31 0.11 0.21 -0.01 0.19 0.03 1.04 1.42 0.63 0.62 0.51 0.85 0.74 0.90 0.11 1.01
3500 || orf19.5087 || BUD6 || || Protein required for Spitzenkorper formation in hyphal cells (wild-type localization of Mlc1p to the Spitzenkorper); localizes to polarisome || 1 0.16 0.18 0.34 -0.02 0.25 -0.02 0.85 0.69 0.45 0.32 0.46 0.47 0.46 0.62 0.36 0.89
3501 || orf19.6534.2 || CRN1 || || Coronin; cortical actin cytoskeletal component; predicted role in regulation of actin patch assembly; rat catheter and Spider biofilm repressed || 1 0.46 0.48 0.35 -0.04 0.21 0.07 1.32 0.96 0.65 0.45 1.09 0.78 0.91 1.12 0.84 1.21
3502 || orf19.729 || || || Adaptor protein required for specific mRNA transport; protein similar but not orthologous to S. cerevisiae She3; transposon mutation affects filamentous growth || 1 0.19 0.23 0.01 0.07 0.01 -0.29 0.60 0.84 0.48 0.33 1.00 0.62 0.26 0.49 0.49 0.45
3503 || orf19.1412 || || || Ortholog of C. dubliniensis CD36 : Cd36_44020, C. parapsilosis CDC317 : CPAR2_302330, Candida tenuis NRRL Y-1498 : CANTEDRAFT_105448 and Debaryomyces hansenii CBS767 : DEHA2C10582g || 1 0.58 0.62 0.22 0.00 0.19 -0.16 1.32 1.74 1.10 0.83 1.52 1.01 0.59 1.10 0.51 1.15
3504 || orf19.4373 || || || Protein similar to S. cerevisiae Fmn1p, which is riboflavin kinase; predicted Kex2p substrate; Hap43p-repressed gene || 1 0.43 0.35 0.08 0.49 -0.27 -0.40 0.93 1.17 0.86 0.93 1.10 1.10 0.43 1.02 0.23 1.07
3505 || orf19.1412 || || || Ortholog of C. dubliniensis CD36 : Cd36_44020, C. parapsilosis CDC317 : CPAR2_302330, Candida tenuis NRRL Y-1498 : CANTEDRAFT_105448 and Debaryomyces hansenii CBS767 : DEHA2C10582g || 1 0.17 0.15 0.60 0.36 0.29 -0.07 0.84 1.13 0.55 0.56 0.95 0.75 0.25 0.62 0.25 0.92
3506 || orf19.200 || || || Putative nuclear RNA-binding protein; Spider biofilm repressed || 1 0.85 0.64 0.45 0.62 0.21 -0.34 1.02 1.69 0.49 0.55 1.41 0.92 0.52 0.77 0.18 1.04
3507 || orf19.519 || || || Ortholog(s) have RNA polymerase I upstream control element sequence-specific DNA binding, RNA polymerase I upstream control element sequence-specific DNA binding transcription factor activity || 1 0.65 0.46 0.47 0.40 -0.02 -0.04 0.56 0.79 0.37 0.40 0.89 0.57 0.29 0.37 0.03 0.93
3508 || orf19.2088 || || || Putative DNA polymerase epsilon subunit D; null mutant is viable but slow-growing and displays abnormal invasive growth on SD and YPD media; Spider biofilm repressed || 1 0.38 0.10 0.01 0.54 -0.11 -0.09 0.50 1.16 0.40 1.34 1.05 0.93 0.14 0.98 0.17 0.95
3509 || orf19.2694 || TYS1 || || Putative tRNA-Tyr synthetase; downregulated upon phagocytosis by murine macrophages; stationary phase enriched protein; Spider biofilm repressed || 1 0.23 0.22 -0.25 0.32 0.30 0.02 0.44 1.00 0.41 0.99 0.85 0.47 0.08 0.60 0.07 0.66
3510 || orf19.4091 || MED18 || || RNA polymerase II mediator complex subunit; rat catheter biofilm repressed || 1 0.51 0.42 -0.01 -0.00 0.14 0.00 0.29 0.89 0.17 0.42 0.53 0.50 0.40 0.42 0.30 0.20
3511 || orf19.4208 || RAD52 || || Required for homologous DNA recombination, repair of UV- or MMS-damaged DNA, telomere length, UV-induced LOH; constitutive expression, MMS-induced; weakly complements S. cerevisiae rad52 mutant; slow growth, increased white-to-opaque switch || 1 0.91 0.88 -0.06 0.29 0.43 -0.43 0.83 1.04 0.10 0.73 0.55 0.81 0.59 0.62 0.53 0.78
3512 || orf19.4713 || || || Ortholog of C. dubliniensis CD36 : Cd36_07300, C. parapsilosis CDC317 : CPAR2_208300, Candida tenuis NRRL Y-1498 : CANTEDRAFT_95879 and Debaryomyces hansenii CBS767 : DEHA2F26246g || 1 0.32 0.76 -0.01 0.07 0.65 -0.17 0.73 0.81 0.28 0.39 0.70 0.55 0.19 0.51 0.54 0.62
3513 || orf19.793 || CAK1 || || Monomeric CDK-activating kinase; functional homolog of S. cerevisiae Cak1p; phosphorylates cyclin-free human CDK2; lacks glycine loop motif; conserved lysine (K36) not required for activity; possibly essential gene (by UAU1 method) || 1 0.61 0.49 0.17 0.20 0.28 -0.06 0.31 0.54 -0.14 0.31 0.54 0.28 0.05 0.41 0.23 0.40
3514 || orf19.2465 || POL32 || || Putative subunit of DNA polymerase delta, involved in chromosomal DNA replication; cell-cycle regulated periodic mRNA expression || 1 0.66 0.30 0.58 0.44 0.82 0.30 0.58 1.24 0.34 0.83 0.83 0.50 0.20 1.08 0.57 0.65
3515 || orf19.4724 || || || Ortholog(s) have RNA binding activity, role in spliceosomal complex assembly and U2-type prespliceosome localization || 1 0.47 0.56 0.40 0.28 0.43 0.10 0.28 0.28 0.33 0.25 0.64 0.35 0.15 0.83 0.05 0.73
3516 || orf19.1998 || || || Ortholog of C. dubliniensis CD36 : Cd36_16140, C. parapsilosis CDC317 : CPAR2_213870, Candida tenuis NRRL Y-1498 : CANTEDRAFT_92202 and Debaryomyces hansenii CBS767 : DEHA2A01980g || 1 0.36 0.50 0.37 0.28 0.37 -0.21 0.24 0.36 0.37 0.37 0.66 0.34 0.12 0.73 0.22 0.53
3517 || orf19.7116 || || || Protein of unknown function; transcript induced in RHE model of oral candidiasis; Spider biofilm repressed || 1 0.34 0.55 0.62 0.24 0.57 0.01 0.06 0.46 0.44 0.34 0.80 0.54 0.48 0.44 0.36 0.60
3518 || orf19.6027 || || || Ortholog of C. dubliniensis CD36 : Cd36_00740, C. parapsilosis CDC317 : CPAR2_110170, Candida tenuis NRRL Y-1498 : CANTEDRAFT_133175 and Debaryomyces hansenii CBS767 : DEHA2D09724g || 1 0.76 1.00 0.38 0.21 1.42 -0.51 0.73 0.49 0.49 0.94 1.45 1.26 0.94 1.21 0.86 1.25
3519 || orf19.5030 || DOS2 || || Protein of unknown function; induced during planktonic growth || 1 0.39 0.40 0.35 0.08 0.71 0.55 0.42 0.60 0.55 -0.02 0.64 0.82 0.79 0.77 0.69 0.28
3520 || orf19.2826 || || || Ortholog of C. dubliniensis CD36 : Cd36_27680, C. parapsilosis CDC317 : CPAR2_801140, Candida tenuis NRRL Y-1498 : CANTEDRAFT_129982 and Debaryomyces hansenii CBS767 : DEHA2E09526g || 1 0.95 0.78 0.94 0.49 0.56 1.23 0.57 0.90 0.32 0.18 0.70 0.40 1.17 0.83 0.54 1.08
3521 || orf19.6506 || || || Ortholog(s) have role in histone deacetylation, negative regulation of antisense RNA transcription, regulation of DNA-dependent DNA replication initiation, transcription elongation from RNA polymerase II promoter || 1 0.50 0.61 0.61 -0.06 1.08 1.04 0.96 0.14 0.53 0.12 0.48 0.41 0.72 0.82 1.08 1.32
3522 || orf19.3821 || || || Ortholog of C. dubliniensis CD36 : Cd36_44290, C. parapsilosis CDC317 : CPAR2_500740, Candida tenuis NRRL Y-1498 : CANTEDRAFT_137302 and Debaryomyces hansenii CBS767 : DEHA2F07326g || 1 0.21 0.31 0.41 0.05 0.50 0.22 0.46 0.49 0.25 0.11 0.41 0.20 0.55 0.53 0.78 0.58
3523 || orf19.3998 || || || Ortholog(s) have Atg8 ligase activity, protein binding, bridging activity and role in C-terminal protein lipidation, CVT pathway, macroautophagy, mitochondrion degradation, piecemeal microautophagy of nucleus || 1 0.25 0.72 0.63 0.29 0.82 0.94 0.21 0.66 0.16 0.53 0.47 0.34 0.61 0.70 0.88 0.87
3524 || orf19.2920 || || || Ortholog(s) have role in ribosome biogenesis and cytosol, ribosome localization || 1 0.41 0.47 0.39 0.14 0.47 0.24 0.10 0.54 0.38 0.37 0.66 0.13 0.38 -0.02 0.46 0.48
3525 || orf19.6354 || || || Ortholog of C. dubliniensis CD36 : Cd36_11870, C. parapsilosis CDC317 : CPAR2_201650, Candida tenuis NRRL Y-1498 : cten_CGOB_00224 and Debaryomyces hansenii CBS767 : DEHA2D04884g || 1 0.98 0.93 0.85 0.86 0.88 0.14 0.64 1.76 0.17 -0.00 1.31 0.88 0.86 0.46 0.26 0.62
3526 || orf19.841 || || || Ortholog(s) have role in Golgi vesicle transport and Golgi membrane localization || 1 0.72 0.67 0.72 0.56 0.50 0.15 0.47 1.17 0.42 0.24 0.92 0.76 0.43 -0.02 0.50 0.55
3527 || orf19.841 || || || Ortholog(s) have role in Golgi vesicle transport and Golgi membrane localization || 1 0.32 0.46 0.41 0.33 0.42 -0.13 0.29 0.84 0.56 0.03 0.60 0.33 0.45 0.01 0.45 0.52
3528 || orf19.7270 || || || Protein of unknown function; Spider biofilm repressed || 1 0.49 0.22 0.40 0.46 0.34 0.03 0.45 0.66 0.73 0.03 0.46 0.45 0.37 0.12 0.67 0.33
3529 || orf19.2009 || PEX12 || || Ortholog(s) have ubiquitin-protein ligase activity, role in protein import into peroxisome matrix and integral to peroxisomal membrane localization || 1 0.45 0.31 0.48 0.16 0.28 0.12 0.54 0.87 0.35 0.10 0.50 0.48 0.54 0.42 0.55 0.43
3530 || orf19.7355 || SSN8 || || Ortholog of S. cerevisiae Ssn8; a component of RNA polymerase II holoenzyme; mutants are viable and are sensitive to hydrogen peroxide medium || 1 0.74 0.17 0.47 0.34 0.36 0.20 0.67 1.10 0.50 0.35 0.35 0.47 0.51 0.49 0.55 0.51
3531 || orf19.6849 || ELC1 || || Putative elongin C; transcript regulated by Nrg1 and Mig1; regulated by Gcn2 and Gcn4 || 1 0.64 0.51 0.59 0.67 0.63 0.37 0.58 1.10 0.85 0.36 0.74 0.36 0.24 0.40 0.40 0.32
3532 || orf19.7537 || BNR1 || || Formin; probable role in hyphal cytoskeletal polarity; synthetic lethality if Bnr1p and Bni1p are absent || 1 0.38 0.88 0.39 0.81 0.65 0.46 0.84 0.93 0.61 0.76 1.15 0.46 0.23 0.68 1.05 1.12
3533 || orf19.692 || || || Protein of unknown function; Hap43-repressed gene; rat catheter and Spider biofilm induced || 1 0.72 1.39 0.81 0.61 1.11 0.63 0.40 1.08 0.59 -0.01 1.49 -0.02 1.46 0.20 1.31 0.92
3534 || orf19.5539 || || || Ortholog(s) have role in retrograde vesicle-mediated transport, Golgi to ER and SNARE complex, integral to cytosolic side of endoplasmic reticulum membrane localization || 1 0.58 0.63 0.73 0.21 0.82 0.34 0.32 0.46 0.30 -0.18 0.79 0.21 1.02 0.32 0.66 0.23
3535 || orf19.3428 || || || Protein of unknown function; flow model biofilm induced || 1 0.57 0.69 0.58 0.37 0.63 0.41 0.89 0.73 0.30 0.01 0.71 0.44 1.13 0.08 1.22 0.38
3536 || orf19.2252 || || || Protein of unknown function; rat catheter biofilm repressed || 1 0.23 0.75 0.17 0.13 0.27 0.28 0.57 0.53 0.05 -0.10 0.54 -0.01 0.74 0.51 0.19
3537 || orf19.7036 || || || Ortholog(s) have phosphatase activator activity, role in actin filament organization, endocytosis, mitochondrion degradation, regulation of growth, response to heat, response to salt stress and cytosol, nucleus localization || 1 0.36 0.49 0.08 0.22 0.17 0.30 0.14 0.50 0.11 0.31 0.42 0.37 0.44 0.59 0.19 0.15
3538 || orf19.4730 || || || Ortholog of S. cerevisiae : YNL050C, C. glabrata CBS138 : CAGL0G01276g, C. dubliniensis CD36 : Cd36_08220, C. parapsilosis CDC317 : CPAR2_804440 and Candida tenuis NRRL Y-1498 : CANTEDRAFT_94168 || 1 0.57 1.14 0.58 0.34 0.32 0.65 0.93 0.68 0.47 0.63 1.09 0.58 0.85 1.20 0.56 0.31
3539 || orf19.2827 || || || Ortholog(s) have structural constituent of cytoskeleton activity || 1 0.73 1.37 0.47 0.57 0.18 0.79 0.75 0.60 0.40 0.19 1.21 0.64 1.42 0.71 0.64 0.84
3540 || orf19.5409 || IST1 || || Protein with a positive role in the multivesicular body sorting pathway; rat catheter biofilm repressed || 1 0.64 0.81 0.64 0.72 0.29 0.66 0.22 0.30 0.17 0.12 0.60 0.55 0.25 0.56 0.75 0.68
3541 || orf19.5409 || IST1 || || Protein with a positive role in the multivesicular body sorting pathway; rat catheter biofilm repressed || 1 0.68 0.61 0.42 0.47 0.22 0.33 0.51 0.40 -0.02 0.07 0.58 0.34 0.23 0.54 0.72 0.56
3542 || orf19.1367 || MTW1 || || Kinetochore component; amount of Nuf2p and Mtw1p protein detected at each centromere is consistent with a single kinetochore microtubule attachment site || 1 1.30 0.98 0.64 0.56 0.54 0.61 0.47 0.81 0.54 0.25 0.54 0.51 0.67 0.91 0.87 1.05
3543 || orf19.4726 || || || Ortholog(s) have calcium ion binding, enzyme activator activity || 1 1.01 0.98 0.52 0.31 0.20 0.35 0.38 0.56 0.28 0.53 0.81 0.41 0.15 0.48 0.60 0.58
3544 || orf19.3970 || || || Putative ribosome biogenesis factor; possibly essential, disruptants not obtained by UAU1 method; rat catheter and Spider biofilm induced || 1 2.19 1.31 0.47 0.69 1.45 1.59 1.15 0.81 0.37 1.26 0.42 0.59 0.97 1.10 1.05
3545 || orf19.3578 || || || Ortholog of C. dubliniensis CD36 : Cd36_19950, C. parapsilosis CDC317 : CPAR2_104135, Candida tenuis NRRL Y-1498 : cten_CGOB_00075 and Debaryomyces hansenii CBS767 : DEHA2F07964g || 1 1.75 1.06 0.69 -0.19 1.51 1.35 1.45 1.70 0.49 1.45 0.50 0.83 0.68 0.84 1.25 1.44
3546 || orf19.7581 || || || Protein with a predicted role in assembly of U2 snRNP into the spliceosome; Spider biofilm induced || 1 1.02 1.02 0.71 0.11 1.07 0.93 0.44 0.85 0.61 0.69 0.59 0.61 0.57 0.59 0.69 1.01
3547 || orf19.6476 || || || Putative protein with a predicted role in exocytic transport from the Golgi; filament induced || 1 0.85 1.16 0.29 0.47 1.26 0.90 0.96 0.61 0.83 1.17 0.66 0.40 1.17 0.46 1.11 0.33
3548 || orf19.4441 || || || Ortholog(s) have DNA replication origin binding, double-stranded DNA binding, single-stranded DNA binding activity || 1 0.34 0.49 0.13 0.19 0.51 0.24 0.43 0.36 0.49 0.23 0.38 0.49 0.35 0.70 0.46 0.41
3549 || orf19.7255 || RPC10 || || Putative RNA polymerase subunit ABC10-alpha of RNA polymerase complexes I, II, and III; flucytosine induced; Spider biofilm induced || 1 1.02 0.74 0.53 0.56 1.48 1.34 1.12 1.72 0.61 1.15 1.16 0.99 0.27 0.91 1.04 0.60
3550 || orf19.7255 || RPC10 || || Putative RNA polymerase subunit ABC10-alpha of RNA polymerase complexes I, II, and III; flucytosine induced; Spider biofilm induced || 1 0.74 0.88 0.22 0.46 1.06 1.17 1.00 1.55 0.55 1.10 1.59 0.98 0.66 0.64 0.77 0.44
3551 || orf19.7255 || RPC10 || || Putative RNA polymerase subunit ABC10-alpha of RNA polymerase complexes I, II, and III; flucytosine induced; Spider biofilm induced || 1 1.06 1.16 0.28 0.50 1.48 1.27 1.43 1.88 0.58 1.13 2.16 1.17 0.50 0.94 0.92 0.53
3552 || orf19.7255 || RPC10 || || Putative RNA polymerase subunit ABC10-alpha of RNA polymerase complexes I, II, and III; flucytosine induced; Spider biofilm induced || 1 1.02 1.15 0.27 0.44 1.39 1.29 1.52 1.87 0.57 1.10 1.97 1.02 0.51 0.73 0.68 0.41
3553 || orf19.7255 || RPC10 || || Putative RNA polymerase subunit ABC10-alpha of RNA polymerase complexes I, II, and III; flucytosine induced; Spider biofilm induced || 1 1.10 1.24 0.55 0.45 1.66 1.23 1.20 1.72 0.63 1.04 2.12 0.74 0.61 0.85 0.86 0.14
3554 || orf19.229 || || || Ortholog(s) have ubiquitin-protein ligase activity, role in protein ubiquitination involved in ubiquitin-dependent protein catabolic process and chromosome, centromeric region, mitotic spindle pole body, nucleus localization || 1 0.91 0.73 0.71 0.42 0.77 0.88 1.03 1.69 1.09 0.21 1.60 0.54 1.23 0.56 0.73 0.87
3555 || orf19.725 || || || Ortholog of C. dubliniensis CD36 : Cd36_31880, C. parapsilosis CDC317 : CPAR2_702220, Candida tenuis NRRL Y-1498 : CANTEDRAFT_115848 and Debaryomyces hansenii CBS767 : DEHA2E06028g || 1 1.26 1.09 0.32 0.18 0.64 0.45 0.93 1.42 0.80 0.21 1.18 0.84 1.45 0.34 0.71 1.18
3556 || orf19.6359 || || || Ortholog(s) have endopeptidase activity, role in mitochondrial respiratory chain complex assembly, proteolysis and mitochondrial inner membrane peptidase complex localization || 1 0.72 0.82 0.58 -0.39 0.75 0.37 0.84 0.79 0.44 0.82 0.97 0.58 0.77 0.61 0.55 0.88
3557 || orf19.6482 || || || Protein of unknown function; induced by nitric oxide independent of Yhb1p; regulated by Sef1, Sfu1, and Hap43; rat catheter biofilm induced || 1 0.67 0.64 0.48 -0.05 0.31 0.32 0.44 0.43 0.22 0.36 0.52 0.31 0.63 0.38 0.48 0.49
3558 || orf19.74 || SEC5 || || Predicted exocyst component; ortholog of S. cerevisiae Sec5p; merged with orf19.75 in Assembly 21 || 1 0.47 0.41 0.11 0.13 0.65 0.52 0.41 0.20 0.17 0.15 0.61 0.29 0.14 0.48 0.91 0.64
3559 || orf19.2982 || || || Ortholog(s) have protein complex scaffold, protein kinase activator activity || 1 1.04 0.72 0.14 0.00 1.02 0.75 0.82 0.53 0.58 0.38 1.19 1.06 0.71 0.93 1.56 1.01
3560 || orf19.2361 || SPT10 || || Ortholog(s) have sequence-specific DNA binding activity || 1 1.26 1.00 0.42 0.30 1.39 1.44 1.20 0.88 0.56 0.44 1.18 0.95 0.81 1.42 1.34 1.36
3561 || orf19.2391 || || || Putative protein of unknown function; Hap43p-repressed gene; S. cerevisiae ortholog YKR023W localizes to mitochondria || 1 0.84 0.87 0.22 0.07 0.88 1.12 1.56 0.68 1.03 0.81 1.43 1.14 0.53 1.54 1.35 1.53
3562 || orf19.190 || || || Ortholog(s) have role in endoplasmic reticulum organization, histone exchange and Swr1 complex, mitochondrion localization || 1 0.36 0.77 0.52 0.28 1.13 1.34 1.06 0.69 0.69 1.04 1.64 1.42 1.76 1.00 1.44 1.36
3563 || orf19.7572 || SPT7 || || Putative SAGA transcriptional regulatory complex subunit; mutation confers hypersensitivity to toxic ergosterol analog, and to amphotericin B || 1 0.43 0.97 -0.15 -0.03 1.36 1.04 0.80 0.80 0.49 0.55 0.97 0.69 1.24 0.80 1.40 0.71
3564 || orf19.7572 || SPT7 || || Putative SAGA transcriptional regulatory complex subunit; mutation confers hypersensitivity to toxic ergosterol analog, and to amphotericin B || 1 0.64 0.70 -0.25 -0.15 1.42 1.08 0.66 1.01 0.53 0.68 1.16 0.89 0.90 1.09 1.67 1.36
3565 || orf19.5275 || || || Ortholog(s) have ATPase activator activity, role in late endosome to vacuole transport via multivesicular body sorting pathway, positive regulation of protein oligomerization and endosome membrane, multivesicular body localization || 1 1.00 0.91 -0.24 -0.26 1.50 1.15 1.13 0.94 0.73 0.95 2.00 0.77 1.49 0.79 1.62 1.51
3566 || orf19.1491 || || || Ortholog(s) have RNA binding activity, role in mRNA splicing, via spliceosome and U1 snRNP, U2-type prespliceosome localization || 1 0.55 0.56 -0.13 0.06 1.08 0.45 0.64 0.84 0.34 0.67 1.29 0.81 1.00 0.47 1.25 0.38
3567 || orf19.6458.1 || || || Ortholog(s) have U6 snRNA binding activity and role in cytoplasmic mRNA processing body assembly, mRNA splicing, via spliceosome || 1 0.78 0.69 -0.01 0.24 1.15 1.17 1.46 1.12 0.85 1.03 1.66 1.10 1.59 0.61 1.60 0.50
3568 || orf19.713 || || || Ortholog(s) have role in apoptotic process and cytoplasm, nucleus localization || 1 0.64 0.65 0.29 0.52 0.98 0.84 1.04 0.84 0.78 0.72 1.41 0.94 1.07 0.58 1.18 0.62
3569 || orf19.6458.1 || || || Ortholog(s) have U6 snRNA binding activity and role in cytoplasmic mRNA processing body assembly, mRNA splicing, via spliceosome || 1 1.24 1.49 0.23 0.42 1.88 1.41 2.22 2.23 1.14 1.66 2.62 1.60 2.01 1.39 2.64 1.49
3570 || orf19.4258 || || || Puttaive pre-mRNA polyadenylation factor; heterozygous null mutant exhibits hypersensitivity to parnafungin and cordycepin in the C. albicans fitness test || 1 0.43 0.34 0.01 0.17 0.76 0.78 0.76 0.95 0.43 0.61 0.93 0.78 0.67 0.38 1.09 0.45
3571 || orf19.248 || APL5 || || Ortholog of S. cerevisiae and S. pombe Apl5; subunit of the AP-3 adaptor complex involved in Golgi-to-vacuole transport; phosphorylated protein; mutant is viable; || 1 1.01 1.08 -0.05 0.08 1.33 1.11 1.60 1.56 1.26 1.44 1.74 1.58 1.01 0.84 1.85 1.69
3572 || orf19.190 || || || Ortholog(s) have role in endoplasmic reticulum organization, histone exchange and Swr1 complex, mitochondrion localization || 1 0.89 0.74 0.32 0.56 1.29 1.28 1.29 1.22 0.72 0.95 1.71 1.61 1.42 0.84 1.59 1.29
3573 || orf19.190 || || || Ortholog(s) have role in endoplasmic reticulum organization, histone exchange and Swr1 complex, mitochondrion localization || 1 0.60 0.62 0.36 0.28 1.10 1.04 1.21 1.11 0.70 0.98 1.44 1.26 1.24 1.07 1.56 1.60
3574 || orf19.190 || || || Ortholog(s) have role in endoplasmic reticulum organization, histone exchange and Swr1 complex, mitochondrion localization || 1 0.58 0.88 0.44 0.34 1.19 1.32 1.18 1.37 0.38 0.80 1.23 1.48 1.26 0.99 1.69 1.51
3575 || orf19.5030 || DOS2 || || Protein of unknown function; induced during planktonic growth || 1 0.68 0.62 0.32 0.35 1.32 1.19 1.03 1.08 0.79 0.46 1.02 1.15 0.97 0.91 1.33 1.14
3576 || orf19.190 || || || Ortholog(s) have role in endoplasmic reticulum organization, histone exchange and Swr1 complex, mitochondrion localization || 1 1.03 0.75 0.26 0.26 1.47 1.56 1.11 1.56 0.85 1.19 1.29 1.54 1.15 1.34 1.60 1.42
3577 || orf19.2391 || || || Putative protein of unknown function; Hap43p-repressed gene; S. cerevisiae ortholog YKR023W localizes to mitochondria || 1 1.07 0.66 0.53 0.65 1.25 1.47 0.71 1.16 0.83 0.90 1.03 1.59 0.96 0.86 1.22 1.27
3578 || orf19.1878 || MED4 || || RNA polymerase II core mediator complex subunit || 1 0.54 0.48 0.36 0.13 0.78 0.30 0.83 0.89 0.44 0.63 0.94 1.00 0.58 0.73 1.06 0.89
3579 || orf19.1878 || MED4 || || RNA polymerase II core mediator complex subunit || 1 0.48 0.62 0.26 0.28 1.02 0.29 0.67 0.56 0.30 0.63 1.00 0.70 0.38 0.64 0.93 0.80
3580 || orf19.5035 || HPC2 || || Ortholog(s) have DNA binding, nucleosome binding activity || 1 0.61 0.72 0.14 0.27 1.04 0.62 1.14 0.70 0.99 0.97 1.73 0.94 0.96 0.75 1.06 0.97
3581 || orf19.6915 || MRE11 || || Putative DNA double-strand break repair factor; involved in response to oxidative stress and drug resistance || 1 0.84 0.44 0.29 0.49 1.28 0.50 1.62 1.31 0.85 0.97 1.28 0.98 1.04 0.79 1.90 1.43
3582 || orf19.7250 || || || Protein of unknown function; rat catheter and Spider biofilm induced || 1 1.19 0.79 -0.07 0.26 1.51 1.25 1.35 2.01 1.32 1.05 1.87 0.87 1.68 1.20 1.32 1.77
3583 || orf19.7250 || || || Protein of unknown function; rat catheter and Spider biofilm induced || 1 0.96 1.05 0.59 0.50 1.27 1.03 1.32 1.92 1.22 0.78 1.45 0.59 1.00 1.35 1.15 1.30
3584 || orf19.5483 || || || Ortholog(s) have GTPase activity, ribosome binding activity, role in positive regulation of translation and mitochondrial matrix, mitochondrial ribosome localization || 1 0.53 0.69 0.87 0.30 1.02 0.90 1.05 1.28 1.20 1.04 1.16 1.00 1.26 1.08 1.43 0.71
3585 || orf19.5441 || ULP3 || || SUMO deconjugation enzyme that removes the small ubiquitin-like modifier (SUMO) from proteins || 1 0.61 0.59 0.77 0.80 0.73 0.90 0.41 0.62 0.39 0.26 0.50 0.76 0.47 0.28 0.37 0.67
3586 || orf19.2410 || SYS3 || || Protein similar to S. cerevisiae Sys3p; putative role in endosome-Golgi vesicle docking; upregulated in biofilm; induced upon adherence to polystyrene || 1 1.07 1.17 1.07 1.29 1.29 1.02 0.71 1.15 0.87 0.56 0.95 1.02 0.88 0.57 0.83 0.82
3587 || orf19.1441 || || || Ortholog of C. dubliniensis CD36 : Cd36_16230, C. parapsilosis CDC317 : CPAR2_213950, Candida tenuis NRRL Y-1498 : CANTEDRAFT_112720 and Debaryomyces hansenii CBS767 : DEHA2A01848g || 1 1.01 0.83 0.70 0.81 0.58 0.70 0.66 0.93 0.79 0.71 0.45 1.05 0.74 0.52 0.69 0.34
3588 || orf19.3608 || MSH3 || || Mismatch repair protein; predicted role in repair of insertion or deletion mutations and removal of nonhomologous DNA ends; rat catheter biofilm repressed || 1 0.61 0.69 0.37 0.38 0.65 0.50 0.51 0.57 0.45 0.45 0.59 0.82 0.51 0.30 0.62 0.19
3589 || orf19.1885 || TAF4 || || Putative TFIID subunit; mutation confers hypersensitivity to toxic ergosterol analog || 1 1.68 1.12 0.77 0.77 1.02 1.14 0.88 1.30 1.04 0.82 1.29 1.00 0.93 0.45 0.70 0.65
3590 || orf19.4766 || ARG81 || || Zn(II)2Cys6 transcription factor; required for utilization of ornithine as a nitrogen source and for wild-type resistance to caffeine; required for yeast cell adherence to silicone substrate || 1 0.83 0.67 0.50 0.28 0.86 0.78 0.77 0.85 0.80 0.40 0.77 0.60 0.47 0.26 0.37 0.79
3591 || orf19.248 || APL5 || || Ortholog of S. cerevisiae and S. pombe Apl5; subunit of the AP-3 adaptor complex involved in Golgi-to-vacuole transport; phosphorylated protein; mutant is viable; || 1 0.88 1.09 0.85 0.65 1.22 1.27 1.46 1.21 1.56 1.22 1.61 1.38 1.24 1.08 1.55
3592 || orf19.4497 || MED8 || || Ortholog(s) have RNA polymerase II core promoter proximal region sequence-specific DNA binding, RNA polymerase II transcription corepressor activity, TBP-class protein binding, structural molecule activity || 1 0.60 0.55 0.71 0.61 0.55 0.78 0.54 0.73 0.63 0.49 0.76 0.88 0.72 0.62 0.68 1.02
3593 || orf19.5568 || VPS51 || || Protein with a role in vacuolar function; null mutant has defect in damaging oral epithelial and vascular endothelial cells; required for normal hyphal growth and stress resistance; induced in presence of host oral or vascular cells || 1 1.31 0.67 0.75 0.54 0.60 0.93 0.98 0.99 0.81 0.69 1.23 1.04 1.04 0.55 0.71 1.41
3594 || orf19.562 || FGR13 || || Protein encoded in retrotransposon Zorro3 with a potential zinc finger; lacks an ortholog in S. cerevisiae; transposon mutation affects filamentous growth || 1 0.79 0.91 0.25 0.43 0.57 0.33 0.75 1.30 0.75 0.53 0.90 0.14 0.74 0.47 0.97 0.72
3595 || orf19.2511.1 || MRPL33 || || Putative mitochondrial ribosomal protein of the large subunit; Ssr1-repressed; rat catheter biofilm induced || 1 1.91 2.11 0.70 0.47 2.13 1.13 2.74 2.51 1.10 0.90 2.42 0.87 2.46 0.87 2.35 0.51
3596 || orf19.117 || || || Ortholog(s) have SNAP receptor activity, role in exocytosis, vesicle fusion and SNARE complex, extrinsic to plasma membrane localization || 1 1.27 1.22 0.14 0.01 1.00 0.35 1.38 1.13 0.39 0.79 1.85 0.73 0.93 0.98 1.77 1.25
3597 || orf19.2410 || SYS3 || || Protein similar to S. cerevisiae Sys3p; putative role in endosome-Golgi vesicle docking; upregulated in biofilm; induced upon adherence to polystyrene || 1 1.45 1.42 0.22 0.37 1.19 0.56 1.17 1.17 0.19 0.71 1.44 0.99 1.04 0.62 1.39 1.22
3598 || orf19.3371 || JAB1 || || Component of the COP9 signalosome (CSN) complex, provides catalytic activity for deneddylation that cleaves the ubiquitin-like protein tag Rub1p off the cullin (Cdc53p) molecule || 1 0.75 0.82 0.29 0.40 0.56 0.25 0.51 0.43 0.21 0.40 0.79 0.58 0.40 0.27 0.96 0.78
3599 || orf19.5985 || || || Ortholog(s) have tubulin binding activity, role in response to cold, tubulin complex assembly and nucleus, polysome, prefoldin complex localization || 1 0.84 0.91 0.42 0.70 1.10 0.75 1.05 1.15 0.67 1.34 1.25 0.80 0.70 0.39 1.40 0.46
3600 || orf19.5985 || || || Ortholog(s) have tubulin binding activity, role in response to cold, tubulin complex assembly and nucleus, polysome, prefoldin complex localization || 1 1.01 0.99 0.44 0.48 1.34 0.56 0.98 1.31 0.45 1.07 1.07 0.88 0.80 0.54 1.45 0.42
3601 || orf19.517 || HAP31 || || CCAAT-binding transcription factor; regulates CYC1; required for resistance to rapamycin, copper; induced in high iron; repressed in low iron; Sef1, Sfu1, and Hap43 regulated; rat catheter and Spider biofilm induced || 1 1.82 1.80 0.89 0.88 1.43 0.93 1.18 1.74 0.98 1.49 2.06 1.01 0.87 1.26 1.91 0.66
3602 || orf19.5772 || || || Ortholog(s) have role in histone exchange and Swr1 complex, cytosol localization || 1 1.49 1.63 0.66 0.68 1.26 0.62 1.13 1.14 0.51 0.76 0.77 0.56 1.07 1.27 1.17 0.80
3603 || orf19.3122.2 || || || Ortholog(s) have role in exocytosis, filamentous growth, mRNA export from nucleus, proteasome assembly, proteasome-mediated ubiquitin-dependent protein catabolic process, regulation of cell cycle || 1 2.11 2.38 0.98 0.77 1.99 0.82 1.60 1.95 0.77 0.59 2.19 0.96 1.48 1.04 1.86 0.66
3604 || orf19.928 || || || Ortholog of C. dubliniensis CD36 : Cd36_50610, C. parapsilosis CDC317 : CPAR2_303690, Candida tenuis NRRL Y-1498 : CANTEDRAFT_93989 and Debaryomyces hansenii CBS767 : DEHA2E15400g || 1 1.22 1.18 0.64 0.54 1.27 1.01 0.64 0.88 0.71 0.37 1.19 0.83 1.16 0.23 1.27 0.61
3605 || orf19.1734 || || || Putative ATPase and nucleosome spacing factor; heterozygous null mutant displays sensitivity to virgineone || 1 0.63 0.61 0.48 0.55 0.90 0.66 0.56 0.62 0.36 0.45 0.66 0.68 0.69 0.55 0.63 0.52
3606 || orf19.1730 || || || HMG-box protein; Spider biofilm repressed || 1 1.09 1.25 0.83 0.86 1.37 0.65 0.99 0.89 0.75 0.37 0.98 0.68 0.91 0.64 1.10 0.88
3607 || orf19.7183 || || || Ortholog(s) have role in protein folding in endoplasmic reticulum and ER membrane protein complex localization || 1 0.87 0.93 0.71 0.65 1.00 0.82 0.45 0.52 0.44 0.23 0.86 0.52 0.54 0.44 0.83 0.59
3608 || orf19.6649 || BRF1 || || Component of the general transcription factor for RNA polymerase III (TFIIIB); possibly an essential gene, disruptants not obtained by UAU1 method || 1 1.34 1.22 0.87 0.96 0.96 1.12 0.88 0.95 0.62 0.58 1.05 0.68 1.06 0.63 1.05 0.43
3609 || orf19.2621 || || || Ortholog(s) have role in mRNA splicing, via spliceosome and U1 snRNP, U2 snRNP, U2-type prespliceosome, U4/U6 x U5 tri-snRNP complex, U5 snRNP, cytosol localization || 1 1.22 1.27 0.61 0.82 1.17 0.84 1.01 1.16 0.28 0.62 1.02 0.35 0.96 0.48 1.22 0.52
3610 || orf19.2621 || || || Ortholog(s) have role in mRNA splicing, via spliceosome and U1 snRNP, U2 snRNP, U2-type prespliceosome, U4/U6 x U5 tri-snRNP complex, U5 snRNP, cytosol localization || 1 1.42 1.36 1.10 0.82 1.47 1.21 1.01 1.37 0.37 0.84 1.23 0.75 0.96 0.69 1.19 1.03
3611 || orf19.4146 || SMD3 || || Putative core snRNP protein; induced upon adherence to polystyrene || 1 1.66 2.00 1.11 1.03 1.70 1.75 1.25 1.71 0.77 1.28 2.05 1.03 1.17 1.07 1.72 1.18
3612 || orf19.2629 || USO1 || || Ortholog(s) have role in ER to Golgi vesicle-mediated transport, Golgi vesicle docking, SNARE complex assembly and ER to Golgi transport vesicle membrane, Golgi membrane localization || 1 2.00 2.20 0.85 0.76 1.78 0.81 1.80 1.65 0.84 1.05 1.65 0.92 1.70 0.74 1.65 1.08
3613 || orf19.2629 || USO1 || || Ortholog(s) have role in ER to Golgi vesicle-mediated transport, Golgi vesicle docking, SNARE complex assembly and ER to Golgi transport vesicle membrane, Golgi membrane localization || 1 2.23 2.36 1.15 0.76 2.03 1.20 2.00 1.15 1.00 1.47 1.72 0.57 1.83 1.16 1.75 1.09
3614 || orf19.6915 || MRE11 || || Putative DNA double-strand break repair factor; involved in response to oxidative stress and drug resistance || 1 1.47 1.38 0.54 0.87 1.72 1.22 1.36 0.98 1.13 1.28 1.44 0.79 1.60 1.01 1.57 0.98
3615 || orf19.6313.2 || MVB12 || || ESCRT-I complex subunit with a role in multivesicular body (MVB) trafficking; mutant displays growth defect on alkaline medium; Hap43p-repressed gene || 1 1.08 1.68 1.00 0.53 1.92 1.28 1.65 1.45 1.10 0.95 1.41 0.68 1.87 1.20 1.94 0.96
3616 || orf19.4988 || || || S. cerevisiae ortholog Sae2 is an endonuclease that processes hairpin DNA structures with the MRX complex, involved in meiotic and mitotic double-strand break repair; upregulated in a cyr1 null mutant || 1 1.11 0.95 0.52 0.79 1.69 1.25 1.53 1.30 0.26 0.62 1.29 1.01 1.49 0.83 1.59 0.75
3617 || orf19.3604 || || || Ortholog(s) have nucleus localization || 1 1.40 1.15 0.09 0.56 1.45 1.17 1.43 1.14 0.45 0.88 1.32 0.38 1.41 0.84 1.80 0.94
3618 || orf19.4473 || SPC19 || || Essential subunit of the Dam1 (DASH) complex, which acts in chromosome segregation by coupling kinetochores to spindle microtubules || 1 1.50 1.57 0.67 0.96 1.86 1.23 0.85 0.76 0.35 0.62 1.83 0.80 1.25 1.30 1.54 1.12
3619 || orf19.4473 || SPC19 || || Essential subunit of the Dam1 (DASH) complex, which acts in chromosome segregation by coupling kinetochores to spindle microtubules || 1 1.61 1.89 0.50 0.56 2.06 1.34 0.80 0.84 0.62 0.92 1.40 0.80 1.17 0.74 1.23 1.37
3620 || orf19.4473 || SPC19 || || Essential subunit of the Dam1 (DASH) complex, which acts in chromosome segregation by coupling kinetochores to spindle microtubules || 1 2.13 1.67 0.41 0.35 2.01 1.45 1.23 1.40 0.54 1.06 1.30 0.63 0.91 1.03 1.42 1.45
3621 || orf19.3688 || || || Ortholog(s) have chromatin DNA binding activity and role in cell wall mannoprotein biosynthetic process, positive regulation of transcription from RNA polymerase II promoter, telomere maintenance || 1 0.99 0.77 0.45 0.41 1.06 0.91 0.93 1.39 0.51 0.40 0.75 0.64 0.86 0.66 0.91 0.60
3622 || orf19.6027 || || || Ortholog of C. dubliniensis CD36 : Cd36_00740, C. parapsilosis CDC317 : CPAR2_110170, Candida tenuis NRRL Y-1498 : CANTEDRAFT_133175 and Debaryomyces hansenii CBS767 : DEHA2D09724g || 1 1.91 1.39 0.93 1.06 1.13 0.82 1.86 1.21 1.45 0.87 1.64 0.71 1.15 0.92 1.38 0.69
3623 || orf19.1367 || MTW1 || || Kinetochore component; amount of Nuf2p and Mtw1p protein detected at each centromere is consistent with a single kinetochore microtubule attachment site || 1 1.31 1.15 0.71 0.45 0.71 0.33 0.82 1.08 0.68 0.70 0.97 0.37 1.27 0.88 0.72 0.44
3624 || orf19.2684 || || || Protein of unknown function; flow model biofilm repressed || 1 2.07 2.09 1.06 1.15 1.86 0.91 2.13 1.91 1.30 1.30 2.38 1.24 1.88 1.57 1.58 0.81
3625 || orf19.725 || || || Ortholog of C. dubliniensis CD36 : Cd36_31880, C. parapsilosis CDC317 : CPAR2_702220, Candida tenuis NRRL Y-1498 : CANTEDRAFT_115848 and Debaryomyces hansenii CBS767 : DEHA2E06028g || 1 1.71 1.70 0.71 0.46 0.60 0.34 1.84 1.42 0.94 0.57 1.66 0.85 1.38 1.41 1.13 0.79
3626 || orf19.5666 || || || Ortholog(s) have transcription coactivator activity || 1 3.01 3.04 1.30 1.27 1.52 0.75 2.79 2.76 1.49 1.57 2.41 1.08 1.98 1.34 1.38 1.09
3627 || orf19.1866 || VMA10 || || Subunit G of the V1 peripheral membrane domain of the vacuolar H+-ATPase (V-ATPase); involved in vacuolar acidification; rat catheter biofilm repressed || 1 2.05 2.12 1.12 0.90 1.19 0.96 2.42 2.04 0.86 1.02 2.10 0.74 2.23 1.12 1.17 1.21
3628 || orf19.1866 || VMA10 || || Subunit G of the V1 peripheral membrane domain of the vacuolar H+-ATPase (V-ATPase); involved in vacuolar acidification; rat catheter biofilm repressed || 1 2.29 2.30 0.69 0.73 1.21 0.68 2.36 2.45 0.87 0.89 2.32 0.78 2.17 1.07 1.57 1.11
3629 || orf19.4825 || || || Mitochondrial matrix protein; required for assembly/stability of the F1 sector of mitochondrial F1F0 ATP synthase at high temperature; rat catheter biofilm repressed || 1 1.99 1.82 0.55 0.51 1.10 0.24 1.86 1.97 0.65 1.02 2.04 0.52 1.14 1.04 1.22 0.66
3630 || orf19.4825 || || || Mitochondrial matrix protein; required for assembly/stability of the F1 sector of mitochondrial F1F0 ATP synthase at high temperature; rat catheter biofilm repressed || 1 2.47 2.17 0.87 0.95 1.29 0.44 1.90 2.81 1.31 1.66 1.84 1.01 1.32 1.58 1.50 1.00
3631 || orf19.4594 || CLC1 || || Clathrin light chain; subunit of the major coat protein involved in intracellular protein transport and endocytosis; rat cathetr and Spider biofilm repressed || 1 1.33 1.56 0.81 0.74 1.06 0.35 1.67 2.06 1.29 1.51 2.03 1.04 1.38 1.60 1.16 0.55
3632 || orf19.6135.1 || SMX4 || || Component of heteroheptameric complexes (Lsm1p, Lsm8p) involved in RNA processing and decay; flucytosine induced || 1 1.26 1.22 0.51 0.66 1.08 0.55 1.37 2.05 0.79 1.05 2.19 0.76 1.23 1.32 1.44 0.72
3633 || orf19.2018.1 || || || PProtein of unknown function; gene has intron; similar to human BLOC1S2 || 1 2.00 1.73 0.97 0.99 1.31 0.76 2.31 2.78 1.97 1.37 1.76 1.22 1.96 1.26 2.33 0.90
3634 || orf19.2511.1 || MRPL33 || || Putative mitochondrial ribosomal protein of the large subunit; Ssr1-repressed; rat catheter biofilm induced || 1 1.25 1.45 0.62 0.12 1.33 0.73 1.91 2.09 1.29 1.42 1.58 0.93 1.36 0.97 1.49 0.56
3635 || orf19.6040 || SNF7 || || ESCRT III complex protein; role in proteolytic activation of Rim101 and Rim8 processing/activation; separable roles in RIM101 pathway and in transport from MVB to vacuole; involved in echinocandin and azole sensitivity || 1 0.74 0.93 0.14 0.14 0.77 0.32 1.12 0.93 0.96 0.55 0.86 0.52 0.93 0.77 0.78 0.47
3636 || orf19.3613 || || || Ortholog(s) have RNA polymerase II core binding, RNA polymerase II core promoter sequence-specific DNA binding transcription factor activity, TFIIF-class binding transcription factor activity, chromatin binding activity || 1 1.06 1.23 0.33 0.35 1.03 0.31 1.27 1.59 0.55 0.80 1.78 0.78 1.64 0.89 1.40 0.76
3637 || orf19.4544 || || || Ortholog of C. dubliniensis CD36 : Cd36_01640, C. parapsilosis CDC317 : CPAR2_106830, Candida tenuis NRRL Y-1498 : cten_CGOB_00039 and Debaryomyces hansenii CBS767 : DEHA2B06578g || 1 0.97 1.03 0.02 0.19 0.85 0.28 1.42 1.51 0.46 0.54 1.61 0.70 1.33 0.94 1.35 1.03
3638 || orf19.6177 || || || Protein of unknown function; Spider biofilm repressed || 1 1.09 1.19 0.21 0.37 0.77 0.88 1.76 1.88 0.71 0.93 2.17 0.82 1.34 0.66 1.33 1.21
3639 || orf19.6177 || || || Protein of unknown function; Spider biofilm repressed || 1 1.02 1.34 0.54 0.53 0.85 0.75 1.68 1.78 0.43 0.65 1.74 0.40 1.25 0.39 1.20 1.17
3640 || orf19.1730 || || || HMG-box protein; Spider biofilm repressed || 1 0.70 0.76 0.25 0.25 0.37 0.36 0.81 0.61 0.28 0.54 0.96 0.31 0.78 0.32 0.74 0.68
3641 || orf19.5174 || TAF19 || || Putative TFIID subunit; mutation confers hypersensitivity to amphotericin B; rat catheter biofilm induced || 1 0.93 0.89 0.23 0.33 0.62 0.68 0.80 1.28 0.35 0.69 1.28 0.71 0.59 0.32 0.92 0.78
3642 || orf19.6325.1 || || || Ortholog(s) have mitochondrion localization || 1 1.52 1.53 0.32 0.77 0.84 1.01 1.41 1.88 0.87 1.01 1.95 1.09 0.63 0.88 1.42 1.40
3643 || orf19.6359 || || || Ortholog(s) have endopeptidase activity, role in mitochondrial respiratory chain complex assembly, proteolysis and mitochondrial inner membrane peptidase complex localization || 1 1.00 1.04 0.23 0.48 0.69 0.72 0.68 1.19 0.82 0.62 1.10 0.89 0.66 0.83 0.83 0.89
3644 || orf19.4713 || || || Ortholog of C. dubliniensis CD36 : Cd36_07300, C. parapsilosis CDC317 : CPAR2_208300, Candida tenuis NRRL Y-1498 : CANTEDRAFT_95879 and Debaryomyces hansenii CBS767 : DEHA2F26246g || 1 0.93 0.95 0.41 0.55 0.94 0.29 1.19 1.57 0.96 0.71 1.33 0.99 0.94 1.12 0.86 1.11
3645 || orf19.4123 || || || Putative THO complex subunit; possibly an essential gene, disruptants not obtained by UAU1 method; protein newly produced during adaptation to the serum || 1 0.92 0.98 0.36 0.45 0.98 0.58 1.33 1.13 0.43 0.75 1.05 0.86 1.03 1.06 1.16 1.05
3646 || orf19.3613 || || || Ortholog(s) have RNA polymerase II core binding, RNA polymerase II core promoter sequence-specific DNA binding transcription factor activity, TFIIF-class binding transcription factor activity, chromatin binding activity || 1 1.47 1.61 0.83 0.56 1.53 0.87 1.48 1.63 1.39 1.31 2.05 1.37 1.97 1.33 1.63 1.52
3647 || orf19.2684 || || || Protein of unknown function; flow model biofilm repressed || 1 1.53 1.74 1.12 0.62 1.53 1.06 1.72 1.80 1.05 1.30 2.15 1.64 1.81 1.69 1.51 1.69
3648 || orf19.117 || || || Ortholog(s) have SNAP receptor activity, role in exocytosis, vesicle fusion and SNARE complex, extrinsic to plasma membrane localization || 1 1.21 1.39 0.85 1.00 1.33 0.94 1.29 1.42 1.04 1.15 1.96 1.12 1.36 1.55 1.78 1.18
3649 || orf19.3949 || || || Ortholog(s) have chromatin binding, histone binding activity || 1 0.84 1.05 0.47 0.55 0.53 0.46 1.10 1.24 1.05 0.70 1.66 1.14 1.39 0.97 1.21 1.17
3650 || orf19.3949 || || || Ortholog(s) have chromatin binding, histone binding activity || 1 0.94 1.08 0.28 0.28 0.69 0.65 1.16 1.45 0.69 0.59 1.80 1.16 1.36 1.13 1.38 0.93
3651 || orf19.4164 || || || Ortholog(s) have mitochondrion, ribosome localization || 1 0.78 0.87 0.24 0.30 0.90 0.73 0.88 1.41 0.52 1.07 1.85 1.19 1.01 1.18 1.21 1.23
3652 || orf19.145 || RPB4 || || Protein similar to S. cerevisiae Rpb4p, which is a component of RNA polymerase II; transposon mutation affects filamentous growth || 1 1.57 1.79 0.63 0.89 1.36 1.56 1.26 1.36 1.01 1.22 2.25 1.59 2.28 2.07 2.19 1.36
3653 || orf19.1111 || || || Ortholog(s) have chromatin binding, protein complex scaffold activity and role in RNA polymerase II transcriptional preinitiation complex assembly, histone acetylation || 1 0.63 0.68 0.63 0.47 0.55 0.75 0.63 1.04 0.78 0.60 1.21 1.10 1.01 1.03 0.83 0.67
3654 || orf19.831 || || || Ortholog of C. dubliniensis CD36 : Cd36_18570, C. parapsilosis CDC317 : CPAR2_211360, Candida tenuis NRRL Y-1498 : CANTEDRAFT_115359 and Debaryomyces hansenii CBS767 : DEHA2D06886g || 1 1.17 1.28 0.83 0.77 0.97 0.48 0.76 0.99 0.31 0.57 1.15 1.06 1.43 0.71 1.34 0.81
3655 || orf19.6135.1 || SMX4 || || Component of heteroheptameric complexes (Lsm1p, Lsm8p) involved in RNA processing and decay; flucytosine induced || 1 0.94 0.90 1.35 0.95 0.82 0.89 1.12 1.47 1.08 0.80 1.60 0.70 1.18 1.23 0.95 0.77
3656 || orf19.517 || HAP31 || || CCAAT-binding transcription factor; regulates CYC1; required for resistance to rapamycin, copper; induced in high iron; repressed in low iron; Sef1, Sfu1, and Hap43 regulated; rat catheter and Spider biofilm induced || 1 0.95 0.94 1.00 0.65 0.49 0.54 0.65 1.18 0.62 0.89 1.33 0.63 0.47 0.79 0.76 0.57
3657 || orf19.6325.1 || || || Ortholog(s) have mitochondrion localization || 1 1.20 1.13 0.74 0.76 0.64 1.19 1.38 1.35 0.95 0.98 1.71 0.61 0.62 0.96 0.86 1.05
3658 || orf19.330.1 || RUB1 || || Ubiquitin-related protein with similarity to mammalian NEDD8; reversible conjugation (neddylation) of the cullin subunit (Cdc53p) modulates the ubiquitin ligase activity of the SCF complexes || 1 1.25 0.99 0.88 0.94 0.51 0.52 1.09 1.10 0.95 0.97 1.08 0.45 0.63 0.43 0.60 0.49
3659 || orf19.4244 || || || Ortholog of Candida albicans WO-1 : CAWG_04619 || 1 1.50 1.86 1.15 0.88 1.15 0.56 1.65 1.11 1.19 1.49 1.86 0.71 2.19 1.23 1.73 0.18
3660 || orf19.4244 || || || Ortholog of Candida albicans WO-1 : CAWG_04619 || 1 1.86 1.64 1.13 0.93 0.99 0.54 2.07 1.14 1.01 1.02 2.11 0.16 1.82 1.09 2.27 0.94
3661 || orf19.745 || VAC8 || || Protein involved in vacuolar inheritance; required for hyphal growth; contains armadillo repeats || 1 0.69 0.69 0.36 0.44 0.38 0.07 0.38 0.42 0.12 0.42 0.63 0.07 0.69 0.28 0.81 0.11
3662 || orf19.4346 || || || Ortholog(s) have protein anchor activity, role in COPII vesicle coating, protein localization to endoplasmic reticulum exit site and ER to Golgi transport vesicle membrane, endoplasmic reticulum exit site localization || 1 0.61 0.57 0.68 0.51 0.90 0.43 0.69 1.10 0.27 0.33 0.80 0.35 0.67 0.51 0.69 0.77
3663 || orf19.7444 || || || Ortholog(s) have cytoplasm, holo TFIIH complex localization || 1 0.90 0.92 0.43 0.31 1.43 1.23 0.66 1.54 0.48 0.18 1.44 0.44 0.97 0.56 0.95 0.96
3664 || orf19.836.1 || || || Ortholog(s) have role in mRNA splicing, via spliceosome and U1 snRNP, U2 snRNP, U2-type prespliceosome, U4/U6 x U5 tri-snRNP complex, U5 snRNP, cytosol localization || 1 0.66 0.92 0.68 0.71 1.32 1.31 0.67 1.37 0.20 0.48 1.19 0.79 0.70 0.63 0.97 0.50
3665 || orf19.811 || || || Protein of unknown function; mutant is viable; Hap43-repressed || 1 0.61 0.56 0.29 0.59 0.91 0.52 0.28 0.55 0.48 0.60 0.94 0.75 0.77 0.24 0.82 0.61
3666 || orf19.6319 || || || Ortholog(s) have mRNA binding, ubiquitin-specific protease activity and role in protein deubiquitination, regulation of ER to Golgi vesicle-mediated transport, regulation of response to osmotic stress, ribophagy || 1 0.35 0.75 0.12 0.22 0.76 0.58 0.37 0.49 0.54 0.56 0.89 0.48 0.94 0.42 0.79 0.44
3667 || orf19.3603 || MFG1 || || Regulator of filamentous growth; required for biofilm formation, virulence; interacts with Flo8 and Mss11 || 1 0.84 0.86 0.43 0.84 1.16 1.25 1.02 1.07 1.05 1.16 1.29 1.29 1.82 1.91 1.46 0.70
3668 || orf19.6147 || || || Putative histone chaperone; role in chromatin remodeling; rat catheter and Spider biofilm repressed || 1 0.73 1.26 0.78 1.03 1.24 1.57 1.02 0.83 1.17 1.41 1.66 1.83 1.21 1.48 0.92 0.36
3669 || orf19.1548 || || || Ortholog(s) have role in mRNA splicing, via spliceosome and U4/U6 x U5 tri-snRNP complex localization || 1 0.48 1.05 0.93 1.01 1.00 0.85 1.04 0.69 0.94 0.76 1.25 0.85 0.78 1.12 1.06 0.51
3670 || orf19.5441 || ULP3 || || SUMO deconjugation enzyme that removes the small ubiquitin-like modifier (SUMO) from proteins || 1 1.03 0.93 0.88 0.40 1.01 0.86 0.83 0.86 0.81 0.65 0.86 0.82 0.82 1.26 0.71 0.61
3671 || orf19.7360 || || || Ortholog(s) have enzyme activator activity, role in histone deubiquitination, regulation of transcription from RNA polymerase II promoter and DUBm complex, SAGA complex localization || 1 0.65 0.86 0.42 0.25 0.91 0.92 1.09 0.82 0.88 0.25 0.91 0.47 1.38 1.13 1.23 1.00
3672 || orf19.4184 || || || Protein with a predicted role in clathrin cage assembly; Hap43-repressed; Spider biofilm repressed || 1 1.14 1.02 0.23 -0.07 1.43 0.82 2.08 1.67 1.07 0.56 1.63 0.33 1.98 1.41 1.38 1.44
3673 || orf19.5287 || || || Ortholog of C. dubliniensis CD36 : Cd36_30690, C. parapsilosis CDC317 : CPAR2_204140, Debaryomyces hansenii CBS767 : DEHA2F16940g and Candida tropicalis MYA-3404 : CTRG_00570 || 1 0.95 0.88 0.68 0.13 0.50 0.52 1.61 1.25 0.83 0.79 1.62 1.02 1.58 1.27 0.90 1.09
3674 || orf19.6534.2 || CRN1 || || Coronin; cortical actin cytoskeletal component; predicted role in regulation of actin patch assembly; rat catheter and Spider biofilm repressed || 1 0.70 0.94 0.69 0.64 0.62 0.56 1.50 1.22 1.16 0.93 1.16 0.85 1.19 0.81 0.82 0.49
3675 || orf19.7193 || || || Specificity factor required for ubiquitination; role in protein targeting to vacuole; involved in ubiquitin-dependent protein catabolism via the multivesicular body sorting pathway; Spider biofilm induced || 1 0.94 1.03 0.19 0.55 1.05 0.71 2.12 1.85 1.55 1.89 1.44 0.81 2.04 2.10 1.08 0.87
3676 || orf19.7193 || || || Specificity factor required for ubiquitination; role in protein targeting to vacuole; involved in ubiquitin-dependent protein catabolism via the multivesicular body sorting pathway; Spider biofilm induced || 1 0.68 0.27 0.20 0.62 0.93 0.99 1.65 1.57 1.19 1.52 1.34 1.14 1.61 1.40 0.87 0.90
3677 || orf19.2055 || NPL6 || || Putative nuclear protein localization factor; Hap43-induced; Spider biofilm repressed || 1 0.81 0.69 0.34 0.08 0.91 0.25 0.65 0.70 0.67 1.12 1.19 0.77 0.60 0.82 0.93 0.56
3678 || orf19.7458 || || || Ortholog of C. dubliniensis CD36 : Cd36_86660, Candida tenuis NRRL Y-1498 : cten_CGOB_00028, Candida tropicalis MYA-3404 : CTRG_05695 and Candida albicans WO-1 : CAWG_02979 || 1 1.15 1.05 0.07 -0.34 1.32 0.49 1.47 0.71 0.77 0.76 1.08 0.41 1.01 0.30 1.14 0.69
3679 || orf19.6967 || USO6 || || Putative vesicular transport protein; transcript induced by filamentous growth; rat catheter biofilm repressed || 1 1.54 1.60 -0.07 0.11 1.83 0.91 1.44 1.46 0.78 1.53 1.58 0.77 1.67 0.62 1.43 0.63
3680 || orf19.5041 || || || Ortholog of C. dubliniensis CD36 : Cd36_43600, C. parapsilosis CDC317 : CPAR2_403780, Candida tenuis NRRL Y-1498 : CANTEDRAFT_93767 and Debaryomyces hansenii CBS767 : DEHA2G16984g || 1 0.99 1.24 0.24 0.12 0.52 -0.03 0.87 0.90 0.08 0.31 0.98 0.48 1.09 0.56 0.61 0.45
3681 || orf19.3617 || GTR1 || || Putative GTP-binding protein; transcript is upregulated in clinical isolates from HIV+ patients with oral candidiasis; (see Locus History Note for Assembly 19 correction) || 1 1.29 1.47 0.19 -0.11 0.69 0.17 0.84 0.96 0.38 0.34 1.41 0.47 0.81 0.18 0.92 0.34
3682 || orf19.3122.2 || || || Ortholog(s) have role in exocytosis, filamentous growth, mRNA export from nucleus, proteasome assembly, proteasome-mediated ubiquitin-dependent protein catabolic process, regulation of cell cycle || 1 2.01 2.29 0.44 0.41 1.57 0.56 1.42 1.52 0.34 0.21 1.94 0.69 1.40 0.12 1.24 0.63
3683 || orf19.6795 || || || Ortholog(s) have enzyme activator activity || 1 1.41 1.56 0.30 0.02 1.37 0.59 1.04 1.22 0.28 0.46 2.13 0.95 0.93 0.67 0.80 0.82
3684 || orf19.5174 || TAF19 || || Putative TFIID subunit; mutation confers hypersensitivity to amphotericin B; rat catheter biofilm induced || 1 0.88 0.88 0.01 0.07 0.58 0.35 0.68 1.03 0.01 0.50 1.55 0.34 0.86 0.20 0.78 0.63
3685 || orf19.4615 || || || Ortholog(s) have histone deacetylase activity || 1 0.94 1.13 0.06 -0.01 0.91 0.72 1.22 1.27 0.75 0.80 1.85 1.18 0.82 0.61 1.09 0.35
3686 || orf19.6357 || || || Ortholog(s) have role in mitotic DNA integrity checkpoint, negative regulation of protein import into nucleus during spindle assembly checkpoint, nucleocytoplasmic transport || 1 0.83 1.05 0.03 0.13 0.73 -0.03 1.07 0.89 0.72 0.69 1.51 1.11 1.20 0.57 1.26 0.38
3687 || orf19.4348 || MED14 || || RNA polymerase II mediator complex subunit || 1 0.69 0.87 -0.19 -0.08 0.74 0.14 0.79 0.87 0.31 0.50 0.83 0.53 1.15 0.66 0.70 0.28
3688 || orf19.1040 || MAD2 || || Protein required for the spindle assembly checkpoint of the cell cycle; necessary for survival in host cell macrophages and for virulence in a mouse model of systemic candidiasis || 1 1.10 1.08 -0.16 0.17 1.31 -0.05 1.09 1.00 0.44 0.62 1.43 0.11 1.30 0.79 0.89 0.71
3689 || orf19.3471 || || || Protein with a predicted anaphase-promoting complex APC subunit 1 CDC26 domain; Hap43-repressed gene || 1 1.11 1.33 0.01 -0.06 1.36 -0.09 1.75 1.32 0.39 1.10 2.05 0.77 1.44 0.92 1.25 1.13
3690 || orf19.5043 || || || Ortholog of C. dubliniensis CD36 : Cd36_43610, C. parapsilosis CDC317 : CPAR2_403770, Debaryomyces hansenii CBS767 : DEHA2G16962g and Pichia stipitis Pignal : PICST_30926 || 1 0.61 0.85 -0.26 0.05 0.97 -0.03 1.09 0.80 0.38 0.80 1.59 0.58 1.04 0.98 0.91 0.62
3691 || orf19.807 || CHS5 || || Putative chitin biosynthesis protein; fungal-specific; repressed upon yeast-to-hypha switch; rat catheter biofilm repressed || 1 1.01 1.57 0.03 0.11 0.89 -0.11 1.02 1.08 0.50 0.72 1.58 0.46 0.86 1.09 1.14 0.71
3692 || orf19.1941 || NUF2 || || Kinetochore component; amount of Nuf2p and Mtw1p protein detected at each centromere is consistent with a single kinetochore microtubule attachment site || 1 1.70 1.81 -0.72 0.74 0.90 -0.35 1.78 1.46 1.20 1.04 2.36 0.95 1.32 1.39 1.65 0.43
3693 || orf19.2622 || YPT31 || || Protein required for resistance to toxic ergosterol analog || 1 0.67 0.74 0.28 0.10 0.25 0.02 0.98 1.01 0.25 0.95 1.19 0.74 0.81 0.42 0.70 0.38
3694 || orf19.7673 || || || Ortholog(s) have mRNA binding activity, role in mRNA splicing, via spliceosome and U1 snRNP, U2-type prespliceosome, U4/U6 x U5 tri-snRNP complex, U5 snRNP, commitment complex, cytosol localization || 1 0.51 0.64 0.34 0.15 0.17 0.21 0.91 1.20 0.37 0.86 1.27 0.60 0.54 0.18 0.48 0.41
3695 || orf19.6184 || || || Protein of unknown function; Spider biofilm repressed || 1 0.98 0.89 0.35 0.77 0.28 0.33 1.31 1.46 0.81 0.95 1.68 0.73 0.43 0.81 0.95 0.56
3696 || orf19.2985 || || || Protein of unknown function; Hap43-repressed gene || 1 0.64 0.64 0.10 0.15 0.38 0.01 0.75 0.93 0.17 0.48 0.90 0.61 0.04 0.35 1.29 0.71
3697 || orf19.1500 || || || Ortholog of C. dubliniensis CD36 : Cd36_16720, C. parapsilosis CDC317 : CPAR2_210210, Candida tenuis NRRL Y-1498 : CANTEDRAFT_128446 and Debaryomyces hansenii CBS767 : DEHA2B04092g || 1 0.51 0.65 0.14 0.09 0.03 -0.11 0.85 0.80 0.07 0.18 1.11 0.64 0.39 0.44 0.92 0.90
3698 || orf19.7335 || PRE8 || || Putative alpha-2_sc subunit of proteasome; macrophage-induced protein; regulated by Gcn2p and Gcn4p; transcription is positively regulated by Tbf1p; stationary phase enriched protein || 1 0.67 0.61 0.12 0.11 0.10 0.06 0.46 0.68 0.07 0.21 0.89 0.40 0.51 0.37 0.85 0.38
3699 || orf19.6795 || || || Ortholog(s) have enzyme activator activity || 1 1.09 0.89 0.27 0.27 0.41 0.43 0.98 1.36 0.38 0.55 1.93 0.85 0.69 0.65 1.50 0.97
3700 || orf19.2549 || SHP1 || || Regulator of the type 1 protein phosphatase Glc7p activity, involved in control of morphogenesis, progression through the cell cycle and response to DNA damage || 1 0.87 0.86 0.00 -0.04 0.38 -0.15 0.89 0.99 0.34 0.55 1.31 0.75 0.42 0.37 0.99 0.86
3701 || orf19.807 || CHS5 || || Putative chitin biosynthesis protein; fungal-specific; repressed upon yeast-to-hypha switch; rat catheter biofilm repressed || 1 1.04 1.02 0.20 0.04 0.54 0.03 1.33 1.39 0.36 0.41 1.38 0.41 0.60 0.69 0.98 0.86
3702 || orf19.4473 || SPC19 || || Essential subunit of the Dam1 (DASH) complex, which acts in chromosome segregation by coupling kinetochores to spindle microtubules || 1 1.28 1.18 0.57 0.43 1.34 0.48 0.79 1.87 0.41 1.02 2.78 0.83 0.70 1.30 1.60 1.27
3703 || orf19.6796 || YSA1 || || Predicted Nudix hydrolase family member with ADP-ribose pyrophosphatase activity; role in metabolism of O-acetyl-ADP-ribose to AMP and acetylated ribose 5'-phosphate; rat catheter biofilm repressed || 1 0.80 0.87 0.10 0.33 0.98 0.68 1.05 1.67 0.72 0.32 2.32 1.30 0.67 0.70 1.30 1.31
3704 || orf19.1885 || TAF4 || || Putative TFIID subunit; mutation confers hypersensitivity to toxic ergosterol analog || 1 0.47 0.28 0.03 0.10 0.49 0.53 0.54 0.90 -0.02 0.14 0.88 0.53 0.23 0.33 0.82 0.60
3705 || orf19.5825 || NCB2 || || Beta subunit of NC2, heterodimeric regulator of transcription; activates CDR1 transcription; possibly an essential gene, disruptants not obtained by UAU1 method; conditional mutants show decreased susceptibility to azoles || 1 0.61 0.80 -0.18 -0.08 1.09 0.71 0.86 1.32 0.09 0.57 1.52 0.72 0.36 0.51 1.27 0.70
3706 || orf19.6916 || || || Ortholog(s) have unfolded protein binding activity, role in mitochondrial proton-transporting ATP synthase complex assembly and mitochondrion localization || 1 0.08 0.51 -0.22 -0.01 0.32 0.64 1.07 1.03 0.40 0.56 1.21 0.95 0.31 0.08 1.06 0.42
3707 || orf19.4324 || || || Has domain(s) with predicted NADH dehydrogenase (ubiquinone) activity, electron carrier activity and membrane localization || 1 0.73 0.67 0.00 0.41 0.43 0.51 1.25 1.21 0.44 1.12 1.65 1.38 0.52 0.22 1.70 0.99
3708 || orf19.5857 || || || Ortholog of C. dubliniensis CD36 : Cd36_84070, C. parapsilosis CDC317 : CPAR2_102720, Candida tenuis NRRL Y-1498 : CANTEDRAFT_98617 and Debaryomyces hansenii CBS767 : DEHA2D07392g || 1 0.14 0.26 0.21 0.08 0.35 0.05 0.51 0.58 0.45 0.29 0.74 0.63 0.07 0.12 0.50 0.31
3709 || orf19.4727 || || || Ortholog(s) have succinate dehydrogenase (ubiquinone) activity || 1 0.92 0.84 0.16 0.28 0.76 0.01 1.07 1.52 0.65 0.80 1.61 0.89 0.35 0.03 1.19 0.72
3710 || orf19.5076 || PFY1 || || Profilin; functional homolog of S. cerevisiae Pfy1; hyphae, macrophage/pseudohyphal-induced; regulated by Nrg1, Tup1; gene lacks intron (unlike S. cerevisiae PFY1); complements growth of S. cerevisiae srv2 mutant; nonessential || 1 0.71 0.62 0.21 0.23 0.57 0.31 1.09 1.23 0.42 0.25 1.34 1.01 0.19 -0.23 0.82 0.32
3711 || orf19.1538 || TLG2 || || Putative syntaxin-like t-SNARE; macrophage/pseudohyphal-repressed || 1 1.02 1.07 0.34 0.36 0.98 0.21 0.65 0.92 0.18 0.25 1.40 0.83 0.88 -0.06 1.32 0.10
3712 || orf19.1538 || TLG2 || || Putative syntaxin-like t-SNARE; macrophage/pseudohyphal-repressed || 1 0.97 1.33 0.56 0.67 1.55 0.48 0.91 1.04 0.57 0.32 1.70 0.84 1.03 -0.05 1.46 0.40
3713 || orf19.3344 || VPS17 || || Ortholog(s) have phosphatidylinositol-3-phosphate binding, protein transporter activity || 1 1.03 0.93 0.34 0.41 0.93 0.64 0.43 0.59 0.12 0.06 0.54 0.22 0.42 0.21 1.14 0.56
3714 || orf19.4307 || || || Ortholog(s) have role in late endosome to vacuole transport via multivesicular body sorting pathway, protein targeting to vacuole and late endosome localization || 1 1.83 2.16 0.57 0.67 1.69 0.73 1.42 1.18 0.69 0.64 1.74 0.50 0.75 0.57 2.22 0.41
3715 || orf19.4307 || || || Ortholog(s) have role in late endosome to vacuole transport via multivesicular body sorting pathway, protein targeting to vacuole and late endosome localization || 1 1.34 1.10 0.51 0.56 0.80 0.62 0.78 1.07 0.23 0.46 1.11 0.62 0.43 0.56 1.33 0.56
3716 || orf19.1936 || SNF1 || || Essential protein; functional homolog of S. cerevisiae Snf1p regulator of sugar metabolism; constitutively expressed; Thr208 phosphorylation may have regulatory role; up-regulation associated with azole resistance; has polyhistidine tract || 1 1.00 0.78 0.65 0.29 0.79 0.35 0.41 0.83 0.31 0.31 0.78 0.47 0.43 0.47 1.34 0.92
3717 || orf19.6027 || || || Ortholog of C. dubliniensis CD36 : Cd36_00740, C. parapsilosis CDC317 : CPAR2_110170, Candida tenuis NRRL Y-1498 : CANTEDRAFT_133175 and Debaryomyces hansenii CBS767 : DEHA2D09724g || 1 0.72 1.33 0.02 0.49 1.16 0.42 0.83 0.76 0.19 0.47 1.34 1.01 1.30 0.67 0.91 1.37
3718 || orf19.145 || RPB4 || || Protein similar to S. cerevisiae Rpb4p, which is a component of RNA polymerase II; transposon mutation affects filamentous growth || 1 0.48 0.46 0.39 0.34 0.34 0.21 0.78 0.63 0.28 0.57 0.98 1.13 1.04 0.41 0.93 0.41
3719 || orf19.2442 || || || Ortholog of S. cerevisiae Shg1; a COMPASS (Set1C) complex subunit that methylates histone H3 on lysine 4 and is required in transcriptional silencing near telomeres; repressed in an azole-resistant strain overexpressing MDR1 || 1 1.36 0.92 0.62 0.27 0.52 0.49 1.46 0.66 0.67 1.17 2.22 1.48 1.05 1.64 1.93 1.24
3720 || orf19.2399 || || || Putative transcription factor with zinc finger DNA-binding motif; similar to bacterial DnaJ; induced in low iron || 1 0.48 0.48 0.27 -0.18 0.43 0.49 1.28 0.54 0.65 1.10 1.52 1.11 0.86 0.65 0.95 1.06
3721 || orf19.488 || MEX67 || || Nuclear export protein; has NTF2-like domain; interacts with Mtr2p via the NTF2-like domain || 1 0.22 0.29 -0.09 -0.09 0.50 0.64 0.46 0.51 0.00 0.51 0.94 0.64 0.81 0.26 0.86 0.71
3722 || orf19.3858 || || || Protein of unknown function; rat catheter and Spider biofilm induced || 1 0.45 0.31 0.20 -0.22 0.79 1.04 0.54 0.41 0.14 0.40 1.28 0.86 0.73 0.17 1.01 0.79
3723 || orf19.2272 || AFT2 || || Putative Aft domain transcription factor; role in regulation of iron metabolism, oxidative stress, adhesion, hyphal growth, colony morphology, virulence; complements S. cerevisiae aft1 mutation; Spider biofilm induced || 1 0.43 0.86 0.25 0.33 0.77 1.37 0.98 1.00 0.35 0.03 1.53 0.45 1.11 0.03 0.89 0.76
3724 || orf19.1678 || || || Protein of unknown function; transcript detected on high-resolution tiling arrays || 1 0.37 0.31 0.07 0.16 1.11 0.88 1.07 1.01 0.76 0.12 1.64 0.58 1.37 0.04 1.36 0.89
3725 || orf19.1619 || || || Putative kinase subunit of RNA polymerase II carboxy-terminal domain kinase I; possibly an essential gene, disruptants not obtained by UAU1 method || 1 0.27 0.28 0.38 0.28 0.99 0.69 0.86 0.92 0.42 0.07 1.22 0.75 0.74 0.53 1.33 0.53
3726 || orf19.5275 || || || Ortholog(s) have ATPase activator activity, role in late endosome to vacuole transport via multivesicular body sorting pathway, positive regulation of protein oligomerization and endosome membrane, multivesicular body localization || 1 0.36 0.24 0.65 0.50 0.76 0.68 0.76 0.95 0.31 0.31 1.08 0.93 0.81 0.41 0.95 0.97
3727 || orf19.3858 || || || Protein of unknown function; rat catheter and Spider biofilm induced || 1 0.34 0.33 0.23 0.33 0.62 0.76 0.12 0.45 -0.03 0.19 0.83 0.41 0.70 0.31 0.52 0.46
3728 || orf19.952 || || || Has domain(s) with predicted DNA binding activity || 1 0.85 0.76 0.24 0.37 1.29 1.23 0.38 0.69 0.44 0.26 0.26 0.38 1.18 0.63 0.73 0.36
3729 || orf19.3806 || || || Ortholog(s) have role in negative regulation of gluconeogenesis, proteasome-mediated ubiquitin-dependent protein catabolic process, traversing start control point of mitotic cell cycle and GID complex, cytoplasm, nucleus localization || 1 0.44 0.42 0.34 0.01 1.05 0.65 0.10 0.01 0.63 0.24 0.41 0.56 0.46 0.75 0.88 0.35
3730 || orf19.6635 || || || Ortholog of C. dubliniensis CD36 : Cd36_31170, C. parapsilosis CDC317 : CPAR2_205340, Candida tenuis NRRL Y-1498 : CANTEDRAFT_133521 and Debaryomyces hansenii CBS767 : DEHA2E21868g || 1 0.55 0.38 0.22 0.19 0.86 0.52 0.18 0.13 0.33 0.31 0.54 0.83 0.49 0.54 0.90 0.44
3731 || orf19.3764 || GSG1 || || Putative subunit of the TRAPP complex; involved in targeting of ER-to-Golgi transport vesicles; flow model biofilm induced || 1 0.91 0.83 0.60 0.61 1.04 0.54 0.34 0.47 0.91 0.45 0.75 1.33 0.49 0.81 0.76 0.65
3732 || orf19.3998 || || || Ortholog(s) have Atg8 ligase activity, protein binding, bridging activity and role in C-terminal protein lipidation, CVT pathway, macroautophagy, mitochondrion degradation, piecemeal microautophagy of nucleus || 1 0.69 0.63 0.65 0.39 0.87 0.76 -0.02 0.38 0.83 0.66 0.59 0.90 0.78 1.01 0.75 0.82
3733 || orf19.4488 || || || Predicted ortholog of S. cerevisiae Swi3, subunit of the SWI/SNF chromatin remodeling complex; possibly an essential gene, disruptants not obtained by UAU1 method || 1 0.72 0.94 0.64 0.53 1.04 0.53 0.23 0.34 0.39 0.06 0.56 0.73 1.37 0.84 0.99 0.52
3734 || orf19.761 || TCO89 || || Putative homolog of S. cerevisiae Tco89p, which is a component of the TOR C1 complex that is involved in the regulation of growth and cell wall integrity; heterozygous null mutant displays sensitivity to rapamycin || 1 0.42 0.29 0.38 0.37 0.46 0.27 -0.01 -0.05 0.19 0.01 0.28 0.41 0.67 0.32 0.67 0.28
3735 || orf19.6635 || || || Ortholog of C. dubliniensis CD36 : Cd36_31170, C. parapsilosis CDC317 : CPAR2_205340, Candida tenuis NRRL Y-1498 : CANTEDRAFT_133521 and Debaryomyces hansenii CBS767 : DEHA2E21868g || 1 0.86 0.47 0.47 0.24 0.77 0.47 0.13 0.13 0.39 -0.11 0.30 0.61 0.54 0.46 1.13 0.69
3736 || orf19.3233 || HSE1 || || ESCRT-0 complex subunit; SH3-domain-containing protein || 1 0.87 0.66 0.82 0.59 0.99 0.83 0.45 0.24 0.38 0.03 0.46 0.78 0.70 0.63 1.33 0.86
3737 || orf19.933 || || || Ortholog(s) have protein homodimerization activity, ubiquitin-protein ligase activity and role in UV-damage excision repair, free ubiquitin chain polymerization, postreplication repair, protein K63-linked ubiquitination || 1 0.43 0.46 0.52 0.15 0.41 0.48 0.32 0.33 0.25 -0.05 0.43 0.53 0.44 0.45 0.73 0.36
3738 || orf19.6220 || || || Ortholog(s) have role in positive regulation of transcription elongation from RNA polymerase II promoter and CCR4-NOT core complex localization || 1 0.43 0.69 0.60 0.11 0.77 0.69 0.48 0.34 0.33 0.27 0.31 0.63 0.82 0.22 0.61 0.57
3739 || orf19.188 || || || Ortholog of Candida albicans WO-1 : CAWG_04234 || 1 1.01 1.06 0.39 -0.07 2.12 0.87 1.13 0.73 0.67 0.77 1.71 0.94 1.41 0.38 1.86 1.06
3740 || orf19.144 || SNU114 || || Protein similar to S. cerevisiae Snu114p, which is an RNA helicase involved in pre-mRNA splicing; likely to be essential for growth, based on an insertional mutagenesis strategy || 1 1.01 0.73 0.18 0.13 1.60 1.01 0.64 0.64 0.06 0.38 0.79 0.90 0.66 0.35 1.27 0.38
3741 || orf19.1296 || || || Ortholog(s) have role in spliceosomal snRNP assembly and U4/U6 x U5 tri-snRNP complex, mitochondrion localization || 1 1.54 1.04 0.11 0.09 1.87 1.42 1.07 1.16 0.06 0.54 1.44 0.93 1.39 0.56 1.74 0.65
3742 || orf19.3256 || SLN1 || || Histidine kinase involved in a two-component signaling pathway that regulates cell wall biosynthesis; mutants are sensitive to growth on H2O2 medium; rat catheter and Spider biofilm induced || 1 1.06 1.20 0.15 0.12 1.45 0.77 0.88 0.99 0.41 0.10 1.09 0.68 1.23 0.81 1.06 0.16
3743 || orf19.1444 || || || Ortholog(s) have phosphatidylinositol-4,5-bisphosphate binding activity, role in actin cortical patch assembly, actin filament organization, endocytosis and actin cortical patch, mating projection tip localization || 1 0.95 0.86 0.38 0.36 1.12 0.68 0.67 0.65 0.12 -0.03 0.59 0.36 1.14 0.31 1.16 0.32
3744 || orf19.6732 || || || Ortholog(s) have cytosol, nucleus localization || 1 0.84 0.87 0.62 1.03 1.30 1.26 0.55 0.41 0.63 -0.05 0.86 0.61 0.65 0.45 0.51 0.92
3745 || orf19.6649 || BRF1 || || Component of the general transcription factor for RNA polymerase III (TFIIIB); possibly an essential gene, disruptants not obtained by UAU1 method || 1 0.71 0.62 0.37 0.27 0.84 0.91 0.25 0.25 -0.00 0.33 0.75 0.34 0.50 0.04 0.60 0.36
3746 || orf19.5833 || || || Ortholog(s) have polyubiquitin binding activity || 1 0.96 0.97 0.70 0.86 1.39 1.42 0.32 0.25 0.46 0.56 0.75 0.71 0.18 0.61 1.46 0.98
3747 || orf19.3726 || || || Ortholog of C. dubliniensis CD36 : Cd36_65640 and Candida albicans WO-1 : CAWG_01583 || 1 0.60 0.54 0.71 0.91 1.36 1.98 0.60 0.79 1.31 0.58 0.90 0.61 0.62 0.56 1.27 1.03
3748 || orf19.4326 || || || Ortholog(s) have role in mRNA cis splicing, via spliceosome, maturation of 5S rRNA and U4/U6 x U5 tri-snRNP complex localization || 1 1.18 1.29 1.01 0.80 1.52 2.09 0.40 0.58 1.12 0.61 0.98 0.40 0.66 0.74 0.68 0.55
3749 || orf19.6102 || RCA1 || || Protein involved in regulation of carbonic anhydrases; controls CO2 sensing; bZIP domain-containing transcription factor of the ATF/CREB family; null mutant displays slow growth, abnormal colony morphology and invasive growth || 1 0.63 0.60 0.69 0.31 1.35 1.33 0.33 0.49 0.65 0.35 0.69 0.31 0.35 0.59 0.60 0.53
3750 || orf19.4033 || PRP22 || || Putative RNA-dependent ATPase; induced upon adherence to polystyrene; induced by Mnl1p under weak acid stress || 1 0.66 0.94 0.63 0.44 1.25 1.35 0.49 0.57 0.54 0.32 0.51 0.31 0.43 0.29 0.83 0.64
3751 || orf19.567 || TFB3 || || Putative C3HC4 zinc finger transcription factor; transcript positively regulated by Tbf1; Spider biofilm induced || 1 0.82 1.08 0.82 0.71 1.60 1.11 0.71 0.80 0.90 0.78 1.21 0.49 0.70 0.63 0.97 0.79
3752 || orf19.1483 || || || Ortholog(s) have copper ion binding activity, role in mitochondrial respiratory chain complex IV assembly and extrinsic to mitochondrial inner membrane, mitochondrial intermembrane space localization || 1 1.31 1.51 1.07 0.98 1.58 1.85 0.76 1.10 1.14 1.24 1.26 1.02 1.01 0.35 1.57 0.88
3753 || orf19.3401 || CTA1 || || Protein similar to S. cerevisiae Mos10p, which affects S. cerevisiae filamentous growth; activates transcription in 1-hybrid assay in S. cerevisiae; protein levels increase under weak acid stress; nonessential || 1 1.03 1.37 1.30 1.24 1.49 1.37 0.77 0.77 1.03 0.92 1.00 0.96 1.08 0.82 1.24 0.72
3754 || orf19.367 || CNH1 || || Na+/H+ antiporter; required for wild-type growth, cell morphology, and virulence in a mouse model of systemic infection; not transcriptionally regulated by NaCl; fungal-specific (no human or murine homolog) || 1 1.11 1.16 1.09 1.32 1.73 1.97 0.75 0.75 0.88 0.92 1.08 0.64 1.09 0.82 1.47 0.86
3755 || orf19.367 || CNH1 || || Na+/H+ antiporter; required for wild-type growth, cell morphology, and virulence in a mouse model of systemic infection; not transcriptionally regulated by NaCl; fungal-specific (no human or murine homolog) || 1 1.02 0.92 1.00 0.99 1.37 1.40 0.80 0.58 0.59 0.52 0.68 0.36 1.18 0.60 1.32 0.49
3756 || orf19.367 || CNH1 || || Na+/H+ antiporter; required for wild-type growth, cell morphology, and virulence in a mouse model of systemic infection; not transcriptionally regulated by NaCl; fungal-specific (no human or murine homolog) || 1 1.04 0.92 0.85 0.50 1.23 1.42 0.72 0.73 0.74 0.57 0.77 0.39 1.16 1.13 1.21 0.35
3757 || orf19.6313.2 || MVB12 || || ESCRT-I complex subunit with a role in multivesicular body (MVB) trafficking; mutant displays growth defect on alkaline medium; Hap43p-repressed gene || 1 1.07 1.08 0.85 0.62 1.91 1.48 1.13 0.67 1.06 1.10 0.98 0.34 1.32 1.20 1.12 0.58
3758 || orf19.3774.1 || || || Ortholog(s) have protein tag activity and role in cell morphogenesis involved in conjugation with cellular fusion, cellular protein localization, cellular protein modification process, mRNA cis splicing, via spliceosome || 1 1.65 1.72 0.77 1.08 1.94 1.99 1.32 1.08 0.96 0.84 1.10 0.81 1.37 1.24 0.98 0.84
3759 || orf19.4326 || || || Ortholog(s) have role in mRNA cis splicing, via spliceosome, maturation of 5S rRNA and U4/U6 x U5 tri-snRNP complex localization || 1 1.63 1.39 0.92 0.60 2.05 2.77 1.14 0.89 0.37 0.36 1.23 0.56 1.08 1.01 1.17 0.54
3760 || orf19.58 || RRP6 || || Putative nuclear exosome exonuclease component; Hap43p-induced gene; mutation confers hypersensitivity to 5-fluorocytosine (5-FC), 5-fluorouracil (5-FU), and tubercidin (7-deazaadenosine) || 1 1.47 1.56 0.68 0.41 2.18 2.68 0.98 1.12 0.26 1.40 1.75 0.49 1.00 1.09 1.52 0.91
3761 || orf19.6685 || ISY1 || || Putative pre-mRNA-splicing factor; mutation confers resistance to 5-fluorocytosine (5-FC); rat catheter biofilm induced || 1 0.86 1.12 0.70 0.68 1.73 1.91 1.04 0.50 0.33 0.63 1.15 0.45 0.77 0.66 0.92 0.75
3762 || orf19.4464 || SEN15 || || Similar to delta subunit of tRNA splicing endonuclease; increased transcription is observed upon fluphenazine treatment || 1 1.01 1.22 0.60 0.70 1.86 1.61 0.78 0.71 0.58 0.76 1.47 0.53 1.14 1.01 1.10 0.79
3763 || orf19.259 || || || Protein with a predicted role in 60S ribosomal subunit assembly; flow model biofilm induced || 1 1.14 1.26 0.98 0.47 1.82 2.10 1.13 0.66 0.56 0.83 1.52 0.38 1.57 0.61 1.48 1.07
3764 || orf19.928 || || || Ortholog of C. dubliniensis CD36 : Cd36_50610, C. parapsilosis CDC317 : CPAR2_303690, Candida tenuis NRRL Y-1498 : CANTEDRAFT_93989 and Debaryomyces hansenii CBS767 : DEHA2E15400g || 1 1.07 1.02 0.81 0.35 1.25 0.96 0.85 0.15 0.88 0.63 0.77 0.46 1.18 0.57 1.12 0.63
3765 || orf19.6506 || || || Ortholog(s) have role in histone deacetylation, negative regulation of antisense RNA transcription, regulation of DNA-dependent DNA replication initiation, transcription elongation from RNA polymerase II promoter || 1 1.00 0.84 0.44 0.53 1.64 1.23 0.89 0.38 1.24 0.56 0.90 0.53 1.20 0.43 1.25 0.49
3766 || orf19.3806 || || || Ortholog(s) have role in negative regulation of gluconeogenesis, proteasome-mediated ubiquitin-dependent protein catabolic process, traversing start control point of mitotic cell cycle and GID complex, cytoplasm, nucleus localization || 1 0.86 0.70 0.51 0.33 1.48 1.07 0.60 0.57 0.86 0.38 0.85 0.85 1.14 0.85 1.35 0.53
3767 || orf19.1574 || || || Putative TFIID subunit involved in RNA polymerase II transcription initiation; possibly an essential gene, disruptants not obtained by UAU1 method || 1 0.96 0.87 0.43 0.62 1.35 1.25 0.87 0.67 0.80 0.28 1.07 0.75 1.12 0.79 1.45 1.15
3768 || orf19.1670 || BRO1 || || Class E vacuolar protein sorting factor; role in transport from multivesicular body to vacuole; not involved in Rim101 pathway; macrophage and pseudohyphal-repressed; flow model biofilm induced || 1 0.72 0.72 0.39 0.37 1.21 1.19 0.29 0.13 0.21 0.01 0.34 0.50 0.55 0.57 1.19 0.68
3769 || orf19.4326 || || || Ortholog(s) have role in mRNA cis splicing, via spliceosome, maturation of 5S rRNA and U4/U6 x U5 tri-snRNP complex localization || 1 1.21 1.01 0.94 0.44 1.92 2.13 0.64 0.64 0.56 0.21 0.79 0.89 0.80 1.27 1.03 1.12
3770 || orf19.4658 || || || RING finger and CHY zinc finger domain-containing protein; mutant are viable || 1 0.54 0.57 0.42 0.21 1.94 1.97 0.36 0.52 0.71 0.29 0.76 0.83 0.52 0.98 1.12 0.87
3771 || orf19.5531 || CDC37 || || Chaperone for Crk1p; interacts with Crk1p kinase domain and with Sti1p; putative phosphorylation site at Ser14; functional homolog of S. cerevisiae Cdc37p; likely to be essential for growth; regulated by Gcn2p and Gcn4p || 1 0.68 0.86 0.48 0.36 1.66 2.03 0.49 0.58 0.62 0.51 1.03 1.06 0.88 0.73 1.32 0.81
3772 || orf19.3321 || MRS7 || || Member of the LETM1-like protein family, mitochondrial membrane protein || 1 0.45 0.81 0.31 -0.07 1.57 1.70 0.43 0.51 0.46 0.37 0.97 0.60 0.39 0.69 1.29 0.76
3773 || orf19.7123 || || || Protein of unknown function; Spider biofilm repressed || 1 0.37 0.55 0.32 0.45 1.27 1.07 0.67 0.50 0.36 0.03 0.74 0.42 0.50 0.33 1.12 0.30
3774 || orf19.3605 || PEX17 || || Putative peroxin || 1 0.82 1.03 0.41 0.73 1.64 1.10 0.61 0.70 0.34 -0.02 1.01 0.72 0.82 0.78 1.27 0.46
3775 || orf19.6360 || || || Protein involved in pre-mRNA splicing; Spider biofilm induced || 1 1.53 2.26 0.83 0.29 2.21 2.53 2.00 0.86 0.69 0.38 1.88 1.25 1.66 1.66 2.47 1.07
3776 || orf19.7141 || UFE1 || || Protein interacting with Sec20p, possibly involved in retrograde transport between the Golgi and the endoplasmic reticulum; functional homolog of S. cerevisiae Ufe1p, which is an ER t-SNARE that mediates the retrograde traffic || 1 0.49 0.46 0.56 0.50 1.23 1.47 0.61 0.75 0.50 0.38 1.20 0.82 0.65 0.52 1.24 0.61
3777 || orf19.1574 || || || Putative TFIID subunit involved in RNA polymerase II transcription initiation; possibly an essential gene, disruptants not obtained by UAU1 method || 1 0.79 0.83 0.81 0.73 1.07 1.54 0.84 1.02 0.43 0.56 1.23 1.10 0.73 0.81 1.64 1.26
3778 || orf19.7141 || UFE1 || || Protein interacting with Sec20p, possibly involved in retrograde transport between the Golgi and the endoplasmic reticulum; functional homolog of S. cerevisiae Ufe1p, which is an ER t-SNARE that mediates the retrograde traffic || 1 0.67 0.73 0.89 0.79 1.16 1.22 0.52 0.87 0.57 0.47 0.98 0.99 0.32 0.52 1.15 0.96
3779 || orf19.187 || || || Predicted ORF in Assemblies 19, 20 and 21; merged with orf19.188 in Assembly 21 || 1 1.09 0.93 0.40 0.43 1.55 1.96 1.12 0.98 1.04 1.05 1.39 1.50 0.22 1.18 1.91 1.42
3780 || orf19.27 || || || Ortholog of C. dubliniensis CD36 : Cd36_20860, C. parapsilosis CDC317 : CPAR2_104250, Candida tenuis NRRL Y-1498 : CANTEDRAFT_115100 and Debaryomyces hansenii CBS767 : DEHA2E10450g || 1 1.53 1.45 0.55 0.62 1.54 1.27 1.52 1.07 0.57 0.11 1.06 0.80 1.22 -0.06 1.63 1.10
3781 || orf19.7642 || || || Ortholog of S. cerevisiae Vps3; CORVET tethering complex component involved in vacuolar protein sorting; Hap43-repressed gene || 1 0.61 0.55 0.15 0.30 0.90 0.92 0.48 0.44 0.42 -0.04 0.55 0.27 0.55 -0.09 0.79 0.74
3782 || orf19.1504 || || || Putative patatin-like phospholipase; fungal-specific (no human or murine homolog) || 1 0.88 0.69 0.63 0.56 0.94 1.26 0.54 0.68 0.45 -0.02 1.08 1.08 0.74 0.01 1.11 1.14
3783 || orf19.1087 || || || Ortholog of C. parapsilosis CDC317 : CPAR2_601130, C. dubliniensis CD36 : Cd36_64620, Lodderomyces elongisporus NRLL YB-4239 : LELG_04885 and Candida orthopsilosis Co 90-125 : CORT_0F02130 || 1 0.59 0.58 0.59 0.69 1.02 0.97 0.51 0.57 0.56 -0.03 0.45 0.76 0.77 0.26 0.92 0.61
3784 || orf19.5539 || || || Ortholog(s) have role in retrograde vesicle-mediated transport, Golgi to ER and SNARE complex, integral to cytosolic side of endoplasmic reticulum membrane localization || 1 0.78 0.78 0.81 0.79 0.80 0.51 0.57 0.48 0.20 0.14 0.69 0.82 0.35 0.08 0.57 0.69
3785 || orf19.4323 || || || Ortholog(s) have phosphatidylinositol-3-phosphate binding activity and endosome localization || 1 0.99 1.33 1.03 0.99 1.05 0.85 0.73 0.00 0.17 0.11 1.11 0.68 0.91 0.26 1.08 0.33
3786 || CaalfMp07 || ATP8 || || Subunit 8 of the F0 sector of mitochondrial F1F0 ATP synthase, which is a large, evolutionarily conserved enzyme complex required for ATP synthesis || 1 2.02 2.12 1.47 1.91 2.18 2.51 1.17 0.93 0.06 -0.20 1.48 0.98 1.44 0.41 1.69 0.69
3787 || orf19.874 || || || Predicted mitochondrial i-AAA protease supercomplex; degrades misfolded mitochondrial proteins; Hap43-repressed gene || 1 1.02 1.21 0.75 0.60 1.54 1.03 0.70 0.85 0.55 0.44 1.04 0.56 0.25 0.09 1.13 0.34
3788 || orf19.7183 || || || Ortholog(s) have role in protein folding in endoplasmic reticulum and ER membrane protein complex localization || 1 0.95 0.96 0.89 0.88 1.06 1.02 0.36 0.87 0.32 0.28 1.06 0.45 0.53 0.10 1.19 0.86
3789 || orf19.6275 || || || Ortholog(s) have cytosol localization || 1 0.98 1.18 0.64 0.63 1.09 1.01 0.30 0.49 0.45 0.31 0.75 0.52 0.88 -0.09 0.56 0.80
3790 || orf19.3401 || CTA1 || || Protein similar to S. cerevisiae Mos10p, which affects S. cerevisiae filamentous growth; activates transcription in 1-hybrid assay in S. cerevisiae; protein levels increase under weak acid stress; nonessential || 1 1.24 1.27 0.89 0.62 1.10 0.93 0.44 0.59 0.53 0.67 0.68 0.65 0.59 0.21 1.19 0.67
3791 || orf19.6275 || || || Ortholog(s) have cytosol localization || 1 1.05 1.07 0.79 0.58 0.81 0.66 0.35 0.46 0.55 0.17 0.74 0.50 0.60 0.05 0.71 0.27
3792 || orf19.5772 || || || Ortholog(s) have role in histone exchange and Swr1 complex, cytosol localization || 1 1.24 1.38 1.16 1.16 1.04 0.78 0.33 0.70 0.63 0.50 0.59 0.63 0.63 0.49 0.80 0.31
3793 || orf19.1301 || || || Ortholog(s) have cytoplasm, nucleus, ribosome localization || 1 2.28 2.34 0.62 1.01 1.12 0.92 0.24 1.35 0.33 0.67 1.40 0.72 1.16 0.94 1.11 0.92
3794 || orf19.1301 || || || Ortholog(s) have cytoplasm, nucleus, ribosome localization || 1 2.20 2.41 0.61 0.84 1.00 0.75 1.41 1.39 -0.07 0.77 1.69 0.69 1.28 0.99 0.94 1.05
3795 || orf19.670 || SMT3 || || SUMO, small ubiquitin-like protein; Smt3p-conjugated proteins localize to septation site and mother side of bud neck; C. albicans septins appear not to be Smt3p-modified, in contrast to S. cerevisiae septins || 1 1.38 1.52 0.56 0.33 0.94 0.48 1.02 1.20 0.59 0.17 1.17 0.68 1.33 0.78 0.89 0.92
3796 || orf19.1925 || TLO5 || || Member of a family of telomere-proximal genes of unknown function; may be spliced in vivo || 1 1.81 1.88 1.14 0.80 1.53 1.36 1.39 1.52 0.41 -0.10 1.10 -0.20 1.58 0.85 0.51 0.94
3797 || orf19.5467 || TLO7 || || Member of a family of telomere-proximal genes of unknown function; may be spliced in vivo; rat catheter biofilm repressed || 1 1.91 1.92 0.95 0.82 1.51 1.26 1.46 1.45 0.44 0.09 0.84 0.09 1.43 1.17 0.64 1.02
3798 || orf19.5700 || TLO11 || || Member of a family of telomere-proximal genes of unknown function; may be spliced in vivo || 1 1.62 1.56 1.13 1.00 1.21 1.29 1.20 1.29 0.56 0.30 0.75 0.03 1.26 0.87 0.63 0.67
3799 || orf19.5700 || TLO11 || || Member of a family of telomere-proximal genes of unknown function; may be spliced in vivo || 1 1.64 1.61 1.15 0.92 1.47 1.49 0.86 1.20 0.54 0.13 0.88 0.34 1.35 1.13 0.75 0.86
3800 || orf19.4054 || CTA24 || || Putative transcription factor; positive regulator of gene expression; Efg1-repressed; member of a family of telomere-proximal genes; transcript upregulated in RHE model of oral candidiasis || 1 1.26 1.47 1.03 0.67 1.13 1.25 1.07 1.11 0.64 0.34 0.88 0.33 1.17 0.81 0.54 1.08
3801 || orf19.7127.1 || || || Putative protein of unknown function, transcript is upregulated in an RHE model of oral candidiasis || 1 1.35 1.74 0.94 0.83 1.22 1.07 1.22 1.49 0.72 0.20 1.08 0.37 1.06 0.42 0.64 0.77
3802 || orf19.2661 || TLO34 || || Non-telomeric member of a family of telomere-proximal genes of unknown function; predicted N-terminus is extended, relative to that of other family members; overlaps orf19.2662 || 1 1.90 1.90 0.81 0.64 1.38 0.89 1.49 1.49 0.62 0.28 1.01 0.09 1.43 0.72 0.76 0.63
3803 || orf19.362 || TLO9 || || Member of a family of telomere-proximal genes of unknown function; Hap43p-repressed gene || 1 1.72 1.87 1.05 0.95 1.33 0.88 1.41 1.49 0.57 0.25 1.07 0.29 1.37 0.76 0.83 0.87
3804 || orf19.7544 || TLO1 || || Member of a family of telomere-proximal genes of unknown function; hypha-induced expression; rat catheter biofilm repressed || 1 1.55 1.61 0.93 0.76 1.23 0.94 1.35 1.32 0.59 0.28 1.05 0.30 1.39 0.93 0.77 0.96
3805 || orf19.3074 || TLO10 || || Member of a family of telomere-proximal genes of unknown function || 1 1.44 1.74 0.94 0.75 1.41 1.06 1.41 1.41 0.63 0.33 1.20 0.28 1.29 0.90 0.77 0.96
3806 || orf19.6337 || TLO13 || || Member of a family of telomere-proximal genes of unknown function; may be spliced in vivo; overlaps orf19.6337.1, which is a region annotated as blocked reading frame || 1 1.60 1.81 1.02 0.84 1.38 1.08 1.36 1.48 0.70 0.61 1.18 0.28 1.48 0.96 0.78 0.85
3807 || orf19.2661 || TLO34 || || Non-telomeric member of a family of telomere-proximal genes of unknown function; predicted N-terminus is extended, relative to that of other family members; overlaps orf19.2662 || 1 1.70 1.77 0.85 0.83 1.41 1.10 1.35 1.65 0.59 0.31 1.23 0.43 1.39 1.00 0.96 0.75
3808 || orf19.7276.1 || TLO4 || || Member of a family of telomere-proximal genes of unknown function; transcript induced in an RHE model of oral candidiasis; Hap43-repressed || 1 1.94 2.13 0.87 0.80 1.64 1.00 1.32 1.78 0.60 0.28 1.49 0.43 1.60 0.93 1.15 0.82
3809 || orf19.6112 || CTA2 || || Putative transcription factor; Med2 mediator domain; activates transcription in 1-hybrid assay in S. cerevisiae; repressed by Efg1; member of a family of telomere-proximal genes; Tbf1-induced || 1 1.95 1.96 0.90 0.73 1.49 1.04 1.45 1.66 0.56 0.15 1.27 0.28 1.59 0.94 0.98 0.81
3810 || orf19.4054 || CTA24 || || Putative transcription factor; positive regulator of gene expression; Efg1-repressed; member of a family of telomere-proximal genes; transcript upregulated in RHE model of oral candidiasis || 1 1.78 1.88 0.81 0.80 1.35 0.84 1.47 1.52 0.59 0.18 1.10 0.39 1.44 0.83 0.93 0.89
3811 || orf19.6112 || CTA2 || || Putative transcription factor; Med2 mediator domain; activates transcription in 1-hybrid assay in S. cerevisiae; repressed by Efg1; member of a family of telomere-proximal genes; Tbf1-induced || 1 1.85 1.88 0.84 0.54 1.44 1.08 1.61 1.55 0.64 0.24 1.24 0.46 1.41 0.87 0.93 1.20
3812 || orf19.7276.1 || TLO4 || || Member of a family of telomere-proximal genes of unknown function; transcript induced in an RHE model of oral candidiasis; Hap43-repressed || 1 1.92 2.00 0.81 0.62 1.47 1.07 1.67 1.61 0.72 0.34 1.37 0.39 1.56 0.87 1.02 1.02
3813 || orf19.3074 || TLO10 || || Member of a family of telomere-proximal genes of unknown function || 1 2.00 2.02 0.81 0.69 1.64 1.20 1.78 1.73 0.76 0.35 1.46 0.63 1.64 1.06 1.18 0.86
3814 || orf19.7544 || TLO1 || || Member of a family of telomere-proximal genes of unknown function; hypha-induced expression; rat catheter biofilm repressed || 1 1.77 1.94 0.70 0.61 1.52 1.03 1.67 1.68 0.61 0.38 1.25 0.32 1.55 0.80 1.01 0.78
3815 || orf19.6337 || TLO13 || || Member of a family of telomere-proximal genes of unknown function; may be spliced in vivo; overlaps orf19.6337.1, which is a region annotated as blocked reading frame || 1 1.64 1.87 0.60 0.58 1.54 1.06 1.69 1.73 0.69 0.34 1.28 0.40 1.52 0.80 1.08 0.88
3816 || orf19.7127.1 || || || Putative protein of unknown function, transcript is upregulated in an RHE model of oral candidiasis || 1 1.83 1.98 0.56 0.44 1.43 0.95 1.65 1.61 0.59 0.37 1.32 0.36 1.48 0.47 0.96 0.53
3817 || orf19.362 || TLO9 || || Member of a family of telomere-proximal genes of unknown function; Hap43p-repressed gene || 1 2.02 2.06 0.65 0.65 1.60 1.12 1.73 1.70 0.67 0.35 1.48 0.27 1.66 0.40 0.99 0.61
3818 || orf19.7272 || || || Protein of unknown function; transcript detected on high-resolution tiling arrays || 1 1.75 1.69 0.81 0.65 2.10 1.25 1.47 1.50 0.74 0.50 1.00 -0.16 1.77 0.96 1.32 0.47
3819 || orf19.7680 || CTA26 || || Putative transcription factor/activator; Med2 mediator complex ddomain; transcript is upregulated in an RHE model of oral candidiasis; member of a family of telomere-proximal genes; Efg1, Hap43-repressed || 1 1.09 1.60 1.13 1.19 0.96 0.74 0.78 1.05 0.44 0.14 0.43 0.08 0.81 0.98 0.16 0.65
3820 || orf19.7680 || CTA26 || || Putative transcription factor/activator; Med2 mediator complex ddomain; transcript is upregulated in an RHE model of oral candidiasis; member of a family of telomere-proximal genes; Efg1, Hap43-repressed || 1 2.12 2.30 1.58 1.30 1.48 1.22 1.49 1.38 0.98 0.43 0.78 0.14 1.28 1.13 0.54 0.69
3821 || orf19.6191 || TLO8 || || Member of a family of telomere-proximal genes of unknown function; may be spliced in vivo || 1 1.64 1.36 1.35 1.30 1.14 1.43 1.09 1.13 0.79 -0.05 0.60 0.02 1.13 0.76 0.52 0.51
3822 || orf19.6191 || TLO8 || || Member of a family of telomere-proximal genes of unknown function; may be spliced in vivo || 1 0.75 0.85 0.85 0.56 0.69 0.89 0.38 0.40 0.19 0.02 0.21 -0.01 0.70 0.44 0.21 0.21
3823 || orf19.1925 || TLO5 || || Member of a family of telomere-proximal genes of unknown function; may be spliced in vivo || 1 1.02 1.12 1.30 1.17 1.02 1.30 0.33 0.67 0.37 0.00 0.35 0.11 0.89 0.89 0.27 0.68
3824 || orf19.6563 || KCH1 || || Ortholog of Kch1 a potassium transporter; mediates K+ influx and activates high-affinity Ca2+ influx system during mating pheromone response in S. cerevisiae; induced by alpha pheromone in SpiderM medium || 1 0.79 1.01 0.94 0.71 1.13 0.88 0.60 0.58 0.47 0.98 0.40 0.33 0.84 0.81 0.57 0.66
3825 || orf19.5012 || || || Ortholog of C. dubliniensis CD36 : Cd36_12740, C. parapsilosis CDC317 : CPAR2_201620, Candida tenuis NRRL Y-1498 : CANTEDRAFT_107586 and Debaryomyces hansenii CBS767 : DEHA2D04994g || 1 0.92 0.92 1.40 1.47 1.00 0.68 0.99 0.84 0.88 0.99 0.79 0.03 0.71 0.49 0.81 0.29
3826 || orf19.5830 || LHS1 || || Protein similar to S. cerevisiae Hsp70p; predicted Kex2p substrate; possibly essential, disruptants not obtained by UAU1 method; flow model biofilm repressed || 1 1.21 1.02 1.24 1.63 0.87 0.69 0.90 0.94 0.59 0.97 0.56 0.05 0.32 0.53 0.57 0.06
3827 || orf19.5830 || LHS1 || || Protein similar to S. cerevisiae Hsp70p; predicted Kex2p substrate; possibly essential, disruptants not obtained by UAU1 method; flow model biofilm repressed || 1 0.89 1.02 0.95 0.88 0.84 0.62 0.84 0.62 0.21 0.91 0.37 0.04 0.18 0.86 0.65 0.35
3828 || orf19.3592 || JEM1 || || Functional homolog of S. cerevisiae Jem1p, which acts with Scj1p and Kar2p (BiP) in protein folding and ER-associated degradation of misfolded proteins, and also has a role in karyogamy; has J domain and 4 tetratricopeptide repeats || 1 0.64 0.76 0.78 0.68 0.64 0.35 0.69 0.44 0.37 0.54 0.19 -0.05 0.56 0.40 0.50 0.29
3829 || orf19.3592 || JEM1 || || Functional homolog of S. cerevisiae Jem1p, which acts with Scj1p and Kar2p (BiP) in protein folding and ER-associated degradation of misfolded proteins, and also has a role in karyogamy; has J domain and 4 tetratricopeptide repeats || 1 1.04 0.90 0.80 0.55 0.80 0.55 0.79 0.51 0.47 0.49 0.41 0.08 0.58 0.51 0.77 0.16
3830 || orf19.3234.1 || SFT1 || || Putative Golgi v-SNARE; Plc1-regulated; Spider biofilm induced || 1 1.51 1.33 1.27 0.99 1.06 0.41 0.77 1.14 0.69 0.86 1.31 0.30 0.74 0.68 0.42 0.11
3831 || orf19.837.1 || INO4 || || Transcription factor; activator that forms a heterodimer with Ino2; likely regulates genes involved in phosphatidylcholine and phosphatidylinositol biosynthesis, fatty acid beta-oxidation, and peroxisome biogenesis; gene has intron || 1 1.93 2.09 1.46 1.09 1.23 0.56 0.90 1.30 0.92 0.94 0.98 0.65 1.14 1.23 0.93 0.58
3832 || orf19.3963 || || || Ortholog(s) have mitochondrion localization || 1 1.04 1.05 0.73 0.66 0.38 0.36 0.46 0.76 0.30 0.69 0.64 0.46 0.52 0.71 0.73 0.54
3833 || orf19.827 || || || Ortholog of C. dubliniensis CD36 : Cd36_18620, C. parapsilosis CDC317 : CPAR2_212480, Candida tenuis NRRL Y-1498 : CANTEDRAFT_115371 and Debaryomyces hansenii CBS767 : DEHA2D06798g || 1 1.53 1.60 1.12 0.61 0.60 0.33 1.26 1.30 1.05 0.75 0.92 0.70 0.32 1.06 0.57 0.74
3834 || orf19.867 || || || Ortholog(s) have superoxide-generating NADPH oxidase activity, role in apoptotic process, regulation of actin cytoskeleton organization and perinuclear endoplasmic reticulum, ribosome localization || 1 0.65 0.71 0.67 0.47 0.31 0.35 0.61 0.61 0.66 0.38 0.19 0.22 0.23 0.32 0.16 0.32
3835 || orf19.827 || || || Ortholog of C. dubliniensis CD36 : Cd36_18620, C. parapsilosis CDC317 : CPAR2_212480, Candida tenuis NRRL Y-1498 : CANTEDRAFT_115371 and Debaryomyces hansenii CBS767 : DEHA2D06798g || 1 1.86 1.38 1.19 1.17 1.25 0.86 1.04 1.43 1.06 1.06 0.49 0.80 0.23 1.01 1.20 1.00
3836 || orf19.7375 || || || Putative U1A component of the U1 snRNP, involved in splicing; contains two RNA recognition motifs (RRMs); ortholog of S. cerevisiae MUD1 || 1 0.72 0.70 0.89 0.49 0.52 0.25 0.55 0.85 0.35 0.51 0.40 0.73 0.56 0.60 0.43 0.50
3837 || orf19.7553 || || || Protein of unknown function; rat catheter biofilm repressed || 1 0.86 0.84 0.69 0.57 0.88 0.65 0.81 1.45 0.03 1.00 0.50 0.85 1.17 0.81 1.01 0.51
3838 || orf19.4855 || BUD31 || || Bud31 ortholog; not subject to mating-type regulation, in contrast to S. cerevisiae Bud31 which has a role in specifying the bud site; Spider biofilm induced || 1 0.86 0.66 0.94 0.76 0.86 1.06 0.60 0.93 0.54 1.16 1.08 0.89 1.27 0.61 1.07 0.48
3839 || orf19.6597 || || || Ortholog(s) have cytoplasm localization || 1 0.89 0.81 0.79 0.46 0.80 0.76 0.35 0.60 0.17 0.93 0.66 0.42 0.41 0.32 0.74 0.06
3840 || orf19.6730 || || || Ortholog(s) have nucleolus localization || 1 1.63 1.49 0.90 0.70 1.25 2.38 0.95 1.63 0.42 1.86 1.56 0.71 1.22 1.44 1.18 0.45
3841 || orf19.2256 || || || Ortholog(s) have cytosol, nucleus localization || 1 0.42 0.76 0.51 0.58 0.54 0.78 0.37 0.70 0.18 0.77 0.53 0.44 0.43 0.81 0.45 0.18
3842 || orf19.3831 || || || Ortholog(s) have telomerase inhibitor activity, role in box C/D snoRNA 3'-end processing, negative regulation of telomere maintenance via telomerase and nucleolus, nucleoplasm localization || 1 0.51 0.95 0.89 0.98 0.47 1.48 0.81 0.69 0.13 1.23 0.37 0.68 0.97 0.64 0.75 0.07
3843 || orf19.7620 || || || Ortholog(s) have role in mRNA splicing, via spliceosome and spliceosomal complex localization || 1 0.90 1.20 0.42 1.07 1.42 1.20 0.77 0.50 0.71 0.96 1.48 -0.11 1.15 1.20 1.36 0.34
3844 || orf19.4101 || || || Ortholog of C. parapsilosis CDC317 : CPAR2_104840, Candida tenuis NRRL Y-1498 : CANTEDRAFT_116070, Debaryomyces hansenii CBS767 : DEHA2F04994g and Pichia stipitis Pignal : psti_CGOB_00085 || 1 1.43 1.11 0.73 0.57 1.24 0.47 1.56 0.80 0.13 0.81 1.36 -0.50 0.71 0.65 0.99 0.32
3845 || orf19.3181.1 || || || Protein of unknown function; involved in secretion of proteins that lack classical secretory signal sequences; Spider biofilm induced || 1 1.06 1.24 0.30 0.59 1.45 0.22 0.93 0.78 -0.22 0.81 1.20 0.35 0.27 0.42 0.98 0.15
3846 || orf19.3234.1 || SFT1 || || Putative Golgi v-SNARE; Plc1-regulated; Spider biofilm induced || 1 1.70 1.97 0.51 0.58 1.54 0.00 1.06 1.20 0.02 0.28 1.79 0.19 0.48 0.19 0.75 0.20
3847 || orf19.4983 || || || Ortholog of C. dubliniensis CD36 : Cd36_12520, C. parapsilosis CDC317 : CPAR2_201720, Candida tenuis NRRL Y-1498 : CANTEDRAFT_108003 and Debaryomyces hansenii CBS767 : DEHA2D05214g || 1 0.91 0.88 -0.05 0.15 0.84 0.30 0.63 1.06 0.34 0.13 1.02 -0.14 0.49 0.02 0.62 0.38
3848 || orf19.2820 || || || Ortholog(s) have nucleocytoplasmic transporter activity, structural constituent of nuclear pore activity || 1 1.20 0.81 -0.13 0.15 0.84 0.28 0.49 0.59 0.47 0.21 0.54 0.03 0.51 0.31 0.59 0.04
3849 || orf19.3774.1 || || || Ortholog(s) have protein tag activity and role in cell morphogenesis involved in conjugation with cellular fusion, cellular protein localization, cellular protein modification process, mRNA cis splicing, via spliceosome || 1 1.55 1.33 -0.08 0.72 1.65 0.91 1.46 1.45 0.47 0.68 1.50 0.33 1.15 0.81 1.37 -0.22
3850 || orf19.702 || || || Ortholog(s) have DNA helicase activity, role in regulation of translational termination and polysome localization || 1 0.79 0.98 -0.15 0.21 1.43 0.74 0.53 0.82 0.37 0.84 0.83 0.12 0.92 0.33 0.75 -0.31
3851 || orf19.652 || || || Ortholog(s) have crossover junction endodeoxyribonuclease activity, role in DNA repair and cytoplasm, nucleus localization || 1 1.06 1.41 -0.40 0.52 1.38 -0.09 1.26 1.00 0.74 1.13 0.90 0.26 1.05 1.45 -0.50
3852 || orf19.1499 || CTF1 || || Putative zinc-finger transcription factor, similar to A. nidulans FarA and FarB; activates genes required for fatty acid degradation; induced by oleate; null mutant displays carbon source utilization defects and slightly reduced virulence || 1 1.17 0.91 0.27 0.64 1.35 0.34 1.40 1.48 1.04 0.96 0.53 0.08 1.45 0.58 0.95 -0.68
3853 || orf19.7221 || SET3 || || NAD-dependent histone deacetylase; mutations affect filamentous growth; genetic evidence suggests Set3/Hos2 function as a complex to regulate white-opaque switching, morphogenesis, and virulence; flow model biofilm induced || 1 0.39 0.56 0.47 0.50 0.79 0.29 0.61 0.67 0.56 0.26 0.45 0.00 0.94 0.36 0.62 -0.06
3854 || orf19.2263 || || || Has domain(s) with predicted adenyl nucleotide binding activity || 1 0.74 1.11 0.24 0.16 1.92 -0.15 1.08 1.32 0.41 0.60 0.82 -0.09 0.93 0.38 0.75 -0.07
3855 || orf19.6931 || || || Putative cleavage factor I subunit; heterozygous null mutant exhibits hypersensitivity to parnafungin and cordycepin in the C. albicans fitness test || 1 0.39 0.15 -0.05 -0.14 0.63 0.05 0.33 0.47 0.32 0.45 0.73 0.11 0.48 0.39 0.18 0.13
3856 || orf19.7036 || || || Ortholog(s) have phosphatase activator activity, role in actin filament organization, endocytosis, mitochondrion degradation, regulation of growth, response to heat, response to salt stress and cytosol, nucleus localization || 1 0.45 0.20 0.11 0.02 0.62 0.36 0.38 0.50 0.08 0.35 0.65 0.29 0.37 0.47 0.47 -0.07
3857 || orf19.4004 || CCT3 || || Putative cytosolic chaperonin Cct ring complex subunit; mutation confers hypersensitivity to cytochalasin D || 1 0.41 0.49 -0.13 0.05 0.81 0.35 0.24 0.56 0.13 0.94 0.50 0.36 0.46 0.44 0.56 0.07
3858 || orf19.1050 || || || Ortholog of S. cerevisiae : YMR087W, C. glabrata CBS138 : CAGL0J01397g, C. dubliniensis CD36 : Cd36_03920, C. parapsilosis CDC317 : CPAR2_107150 and Pichia stipitis Pignal : PICST_61741 || 1 0.87 0.34 -0.09 -0.17 1.03 0.57 0.31 0.90 0.38 0.67 0.61 0.28 0.71 0.27 0.82 0.54
3859 || orf19.7458 || || || Ortholog of C. dubliniensis CD36 : Cd36_86660, Candida tenuis NRRL Y-1498 : cten_CGOB_00028, Candida tropicalis MYA-3404 : CTRG_05695 and Candida albicans WO-1 : CAWG_02979 || 1 1.34 0.75 -0.20 -0.00 0.65 0.25 1.44 1.39 0.74 0.79 0.49 -0.03 0.76 0.37 0.75 0.70
3860 || orf19.7458 || || || Ortholog of C. dubliniensis CD36 : Cd36_86660, Candida tenuis NRRL Y-1498 : cten_CGOB_00028, Candida tropicalis MYA-3404 : CTRG_05695 and Candida albicans WO-1 : CAWG_02979 || 1 1.14 0.99 -0.31 0.02 0.59 0.54 1.52 0.91 0.91 0.94 0.79 0.13 0.68 0.14 1.29 0.32
3861 || orf19.7458 || || || Ortholog of C. dubliniensis CD36 : Cd36_86660, Candida tenuis NRRL Y-1498 : cten_CGOB_00028, Candida tropicalis MYA-3404 : CTRG_05695 and Candida albicans WO-1 : CAWG_02979 || 1 0.81 0.99 -0.26 -0.12 0.92 0.59 1.20 0.82 0.59 0.66 0.41 0.29 0.44 0.46 1.05 0.92
3862 || orf19.7458 || || || Ortholog of C. dubliniensis CD36 : Cd36_86660, Candida tenuis NRRL Y-1498 : cten_CGOB_00028, Candida tropicalis MYA-3404 : CTRG_05695 and Candida albicans WO-1 : CAWG_02979 || 1 0.75 1.01 -0.14 -0.15 0.74 0.30 1.05 0.87 0.80 0.75 0.73 0.21 0.98 0.83 1.09 0.99
3863 || orf19.1805 || PEX14 || || Ortholog(s) have peroxisome matrix targeting signal-1 binding, peroxisome matrix targeting signal-2 binding, protein binding, bridging activity || 1 0.12 0.76 -0.24 -0.12 0.47 0.84 1.01 0.91 0.53 0.84 0.69 0.53 0.68 0.63 1.09 0.31
3864 || orf19.4204 || || || Ortholog(s) have structural constituent of ribosome activity and mitochondrial small ribosomal subunit localization || 1 0.80 0.94 -0.02 -0.28 0.54 0.56 1.24 1.39 0.69 1.58 1.00 0.44 1.17 0.19 1.39 -0.17
3865 || orf19.5510 || || || Ortholog(s) have role in chromatin silencing at telomere, negative regulation of transcription from RNA polymerase II promoter by pheromones and CHRAC localization || 1 1.06 0.85 0.14 0.53 0.44 0.32 1.08 1.45 0.00 1.17 1.34 0.42 1.18 0.64 1.14 0.11
3866 || orf19.576 || CTF8 || || Putative kinetochore protein with a predicted role in sister chromatid cohesion; repressed during the mating process; flow model biofilm induced || 1 0.61 0.58 0.02 0.08 0.19 0.23 0.94 1.90 0.37 1.96 1.29 0.32 0.50 0.56 1.04 0.72
3867 || orf19.4727 || || || Ortholog(s) have succinate dehydrogenase (ubiquinone) activity || 1 0.40 0.30 0.22 0.13 0.26 -0.20 0.66 0.89 0.42 0.65 0.65 0.36 0.17 0.24 0.69 0.23
3868 || orf19.7664 || || || Ortholog(s) have nucleolus localization || 1 1.53 1.45 0.04 0.48 1.62 1.67 1.04 1.70 0.20 1.38 1.21 0.11 0.02 0.63 0.69 0.57
3869 || orf19.4761 || HST1 || || Putative histone deacetylase, involved in regulation of white-opaque switching || 1 0.37 0.50 -0.12 0.22 0.76 0.68 0.06 0.62 -0.11 0.54 0.62 0.35 -0.04 0.11 0.27 0.49
3870 || orf19.4192.1 || || || Ortholog of C. parapsilosis CDC317 : CPAR2_602880, C. dubliniensis CD36 : Cd36_60590, Candida tenuis NRRL Y-1498 : CANTEDRAFT_115034 and Debaryomyces hansenii CBS767 : DEHA2F15334g || 1 0.75 0.58 0.55 0.23 1.03 0.62 0.57 0.88 -0.15 0.56 1.14 0.30 -0.39 0.15 0.49 0.94
3871 || orf19.4192.1 || || || Ortholog of C. parapsilosis CDC317 : CPAR2_602880, C. dubliniensis CD36 : Cd36_60590, Candida tenuis NRRL Y-1498 : CANTEDRAFT_115034 and Debaryomyces hansenii CBS767 : DEHA2F15334g || 1 1.03 1.18 0.39 0.22 1.48 0.91 0.75 0.89 -0.09 0.63 1.12 0.58 -0.24 0.23 0.42 0.71
3872 || orf19.396 || EAF6 || || Subunit of the NuA4 histone acetyltransferase complex; Hap43-repressed; Spider biofilm repressed || 1 1.14 1.22 0.60 0.32 0.97 0.79 0.77 0.94 0.56 0.12 0.86 0.49 -0.15 0.12 0.23 1.15
3873 || orf19.7149 || || || Putative GTPase inhibitor; predicted role in endocytosis, protein targeting to vacuole; rat catheter biofilm repressed || 1 0.92 0.88 0.04 -0.12 1.00 0.64 0.27 0.67 -0.18 -0.20 1.24 0.14 0.11 -0.09 0.24 1.05
3874 || orf19.542.2 || MIM1 || || Predicted mitochondrial protein involved in outer membrane protein import; rat catheter biofilm repressed || 1 0.37 0.47 0.06 -0.27 0.63 0.38 0.21 0.39 0.10 0.05 0.38 0.09 0.04 -0.00 0.24 0.32
3875 || orf19.7444 || || || Ortholog(s) have cytoplasm, holo TFIIH complex localization || 1 0.56 0.53 0.08 -0.17 1.25 0.92 0.92 0.53 0.30 0.23 1.27 -0.07 0.09 0.19 0.76 0.96
3876 || orf19.6275 || || || Ortholog(s) have cytosol localization || 1 0.78 0.88 0.34 -0.07 0.37 0.61 0.08 0.05 0.17 0.12 0.76 0.53 0.12 0.00 0.51 0.40
3877 || orf19.4353 || ULP2 || || SUMO deconjugation enzyme; removes the small ubiquitin-like modifier (SUMO) from proteins; Spider biofilm induced || 1 0.75 0.88 0.47 0.34 0.50 0.62 0.23 0.23 0.13 -0.17 0.49 0.31 0.11 0.02 0.26 0.67
3878 || orf19.4353 || ULP2 || || SUMO deconjugation enzyme; removes the small ubiquitin-like modifier (SUMO) from proteins; Spider biofilm induced || 1 0.91 0.87 0.64 0.28 0.72 0.70 0.37 0.22 0.12 -0.21 0.70 0.59 0.25 0.35 0.38 0.72
3879 || orf19.2710 || || || Ortholog(s) have enzyme activator activity, role in chromosome segregation and cytoplasm, nucleus localization || 1 1.36 1.24 0.57 0.41 1.65 1.11 0.47 0.39 0.35 -0.04 1.27 0.56 0.19 0.52 1.05 0.67
3880 || orf19.2710 || || || Ortholog(s) have enzyme activator activity, role in chromosome segregation and cytoplasm, nucleus localization || 1 0.75 0.66 0.43 0.32 1.03 0.61 -0.04 0.33 0.35 -0.24 0.81 0.28 0.07 0.14 0.60 0.80
3881 || orf19.4473 || SPC19 || || Essential subunit of the Dam1 (DASH) complex, which acts in chromosome segregation by coupling kinetochores to spindle microtubules || 1 2.02 1.65 0.43 0.46 1.83 1.35 0.05 0.50 0.24 0.66 1.22 1.01 0.71 0.79 0.92 1.12
3882 || orf19.6448 || || || Protein of unknown function; Spider biofilm repressed || 1 0.53 0.69 0.52 0.31 0.77 0.27 0.08 0.25 -0.22 0.02 0.59 0.25 0.40 0.36 0.56 0.38
3883 || orf19.6448 || || || Protein of unknown function; Spider biofilm repressed || 1 0.56 0.61 0.35 -0.00 0.78 0.26 0.16 0.25 -0.14 -0.12 0.67 0.01 0.28 -0.02 0.50 0.27
3884 || orf19.7123 || || || Protein of unknown function; Spider biofilm repressed || 1 0.48 0.51 0.54 0.23 0.89 0.95 0.69 0.26 0.17 -0.32 0.42 0.03 0.44 0.00 0.48 0.36
3885 || orf19.7642 || || || Ortholog of S. cerevisiae Vps3; CORVET tethering complex component involved in vacuolar protein sorting; Hap43-repressed gene || 1 0.56 0.74 1.01 0.21 1.14 0.83 0.92 0.63 -0.06 -0.09 0.84 0.68 0.44 0.23 0.59 0.82
3886 || orf19.4203 || || || Ortholog(s) have role in nuclear pore organization, spindle pole body duplication and nuclear pore transmembrane ring, spindle pole body localization || 1 0.37 0.09 0.52 0.24 0.71 0.60 0.15 0.14 -0.16 -0.09 0.26 0.35 0.39 0.16 0.38 0.57
3887 || orf19.5277 || || || Ortholog(s) have role in nuclear-transcribed mRNA catabolic process, 3'-5' exonucleolytic nonsense-mediated decay, protein ubiquitination and cytoplasm, nucleolus, polysome localization || 1 0.54 0.70 0.21 -0.43 0.93 1.23 0.53 0.03 0.31 0.46 0.64 0.84 0.83 0.66 0.21 0.97
3888 || orf19.7581 || || || Protein with a predicted role in assembly of U2 snRNP into the spliceosome; Spider biofilm induced || 1 0.83 0.89 0.28 -0.41 0.95 0.65 0.68 0.38 0.34 0.31 0.50 0.39 0.84 0.76 0.32 0.90
3889 || orf19.5812 || || || Ortholog of S. cerevisiae Ett1, a nuclear protein that inhibits replication of Brome mosaic virus; early-stage flow model biofilm induced || 1 1.06 1.04 0.52 -0.58 1.50 1.59 0.90 0.90 0.79 -0.00 1.09 0.66 0.78 0.22 -0.16 1.01
3890 || orf19.396 || EAF6 || || Subunit of the NuA4 histone acetyltransferase complex; Hap43-repressed; Spider biofilm repressed || 1 0.69 0.87 0.16 -0.18 1.07 0.85 0.89 1.04 0.67 0.22 1.34 0.66 0.47 0.56 0.09 1.28
3891 || orf19.2869 || || || Ortholog of C. dubliniensis CD36 : Cd36_46110, Candida tropicalis MYA-3404 : CTRG_03792 and Candida albicans WO-1 : CAWG_03165 || 1 1.07 1.17 0.16 -0.00 1.11 1.01 -0.09 0.76 0.58 -0.34 1.01 0.66 0.69 0.19 1.41
3892 || orf19.7204 || || || Ortholog(s) have glyoxysome localization || 1 1.18 1.09 0.35 0.65 0.69 0.56 1.24 1.35 0.08 -0.06 0.64 0.42 0.62 1.41 1.43 0.98
3893 || orf19.6849 || ELC1 || || Putative elongin C; transcript regulated by Nrg1 and Mig1; regulated by Gcn2 and Gcn4 || 1 0.98 0.45 0.70 0.24 0.66 0.50 0.96 1.09 0.41 -0.11 1.16 0.16 0.39 0.37 0.58 0.31
3894 || orf19.3421.1 || MED19 || || RNA polymerase II mediator complex subunit || 1 0.76 1.89 0.84 0.75 0.62 0.09 1.71 1.11 0.25 0.54 1.31 0.32 0.55 0.32 1.27 0.50
3895 || orf19.2568 || IFU5 || || Predicted membrane protein; estradiol-induced; upregulation associated with CDR1 and CDR2 overexpression or fluphenazine; putative drug-responsive regulatory site; similar to S. cerevisiae Wwm1p; Hap43-repressed; Spider biofilm repressed || 1 0.46 0.61 0.77 0.77 0.17 0.28 0.52 0.65 0.35 -0.15 0.62 0.46 0.38 0.31 1.14 0.23
3896 || orf19.6351 || || || Ortholog of C. dubliniensis CD36 : Cd36_11880, Candida tenuis NRRL Y-1498 : cten_CGOB_00231, Debaryomyces hansenii CBS767 : DEHA2D04928g and Pichia stipitis Pignal : PICST_29234 || 1 0.55 0.66 0.55 0.72 0.22 -0.24 0.68 0.59 -0.03 0.00 0.57 0.28 0.38 0.30 1.18 0.42
3897 || orf19.2013 || KAR2 || || Similar to Hsp70 family chaperones; role in translocation of proteins into the ER; induced in high iron; protein present in exponential and stationary growth phase yeast cultures; flow model and Spider biofilm repressed || 1 0.48 0.55 0.37 0.58 -0.10 0.18 0.70 0.79 0.16 0.58 0.92 0.21 0.49 0.44 1.49 0.52
3898 || orf19.2013 || KAR2 || || Similar to Hsp70 family chaperones; role in translocation of proteins into the ER; induced in high iron; protein present in exponential and stationary growth phase yeast cultures; flow model and Spider biofilm repressed || 1 0.67 0.72 0.38 0.51 0.38 0.29 0.91 0.91 0.30 0.70 1.18 0.43 0.53 0.59 1.80 0.85
3899 || orf19.2985 || || || Protein of unknown function; Hap43-repressed gene || 1 0.71 0.43 0.28 0.37 0.11 -0.15 0.38 0.79 0.08 0.44 0.60 0.51 0.11 0.21 1.05 0.44
3900 || orf19.36 || || || Component of the conserved oligomeric Golgi complex; predicted to mediate fusion of transport vesicles to Golgi compartments; clade-associated gene expression || 1 0.78 0.74 0.13 0.20 -0.01 -0.34 0.41 0.29 -0.01 0.17 0.66 0.71 0.46 0.41 0.81 0.41
3901 || orf19.213 || || || Ortholog(s) have role in ubiquitin-dependent protein catabolic process and nucleus, proteasome regulatory particle, lid subcomplex, proteasome storage granule localization || 1 1.35 1.13 0.08 0.28 0.22 -0.67 0.76 0.84 -0.46 -0.01 1.08 0.37 0.34 -0.01 1.46 0.80
3902 || orf19.213 || || || Ortholog(s) have role in ubiquitin-dependent protein catabolic process and nucleus, proteasome regulatory particle, lid subcomplex, proteasome storage granule localization || 1 1.46 1.39 0.26 0.47 0.20 -0.36 0.66 0.92 -0.19 0.26 1.38 0.57 0.51 0.39 1.47 0.46
3903 || orf19.213 || || || Ortholog(s) have role in ubiquitin-dependent protein catabolic process and nucleus, proteasome regulatory particle, lid subcomplex, proteasome storage granule localization || 1 1.08 1.17 0.42 0.56 -0.09 -0.08 0.56 0.75 -0.28 0.25 1.25 0.25 0.17 0.21 1.04 0.47
3904 || orf19.2411 || SYN8 || || Putative endosomal SNARE; role in protein transport; rat catheter and Spider biofilm induced || 1 1.05 0.96 0.52 0.70 0.43 0.04 0.54 0.90 -0.53 -0.14 0.90 0.16 0.17 0.37 1.05 0.11
3905 || orf19.121 || ARC18 || || Putative ARP2/3 complex subunit; mutation confers hypersensitivity to cytochalasin D || 1 1.00 0.76 0.25 0.24 0.49 -0.02 0.35 0.74 -0.09 -0.07 1.18 0.41 0.22 0.25 0.51 0.32
3906 || orf19.6582 || PRE10 || || Alpha7 (C8) subunit of the 20S proteasome; multiple phosphorylated residues; transcript induced upon filamentous growth; Spider biofilm repressed || 1 0.55 0.50 0.33 0.59 0.10 -0.16 0.20 0.55 0.13 0.14 0.75 0.46 0.08 0.12 0.49 0.36
3907 || orf19.6551 || || || Ortholog(s) have SNAP receptor activity, role in Golgi vesicle transport, vesicle fusion and Golgi medial cisterna, SNARE complex localization || 1 1.28 1.11 1.04 0.92 1.02 0.76 0.73 1.13 0.54 0.45 1.49 1.11 0.14 -0.07 1.67 0.49
3908 || orf19.5522 || || || Ortholog of C. dubliniensis CD36 : Cd36_62760, C. parapsilosis CDC317 : CPAR2_601700, Candida tenuis NRRL Y-1498 : CANTEDRAFT_115220 and Debaryomyces hansenii CBS767 : DEHA2A06666g || 1 1.51 1.00 0.49 1.11 0.56 0.42 0.57 0.94 0.11 0.11 1.69 1.02 0.40 -0.15 1.48 0.28
3909 || orf19.3661 || || || Putative deubiquitinating enzyme; induced by Mnl1 under weak acid stress || 1 1.11 0.95 0.50 0.53 0.69 0.28 0.48 0.77 0.45 0.05 1.76 0.59 0.25 -0.35 0.59 0.54
3910 || orf19.6528 || || || Ortholog of C. dubliniensis CD36 : Cd36_71740, C. parapsilosis CDC317 : CPAR2_703440, Candida tenuis NRRL Y-1498 : CANTEDRAFT_102923 and Debaryomyces hansenii CBS767 : DEHA2C03190g || 1 0.52 0.43 0.04 0.75 0.67 0.30 0.26 0.82 0.23 -0.00 1.07 0.47 0.47 -0.23 0.63 0.44
3911 || orf19.5053 || || || Ortholog(s) have acetyltransferase activity, chromatin binding activity || 1 1.16 0.96 0.66 1.02 0.56 -0.03 0.88 0.96 0.69 0.56 1.12 0.34 0.98 -0.02 0.86 -0.76
3912 || orf19.2598 || VMA4 || || H+ transporting ATPase E chain; transcript regulated by Mig1; caspofungin repressed; protein level decreases in stationary phase cultures; rat catheter biofilm repressed || 1 1.06 0.95 0.06 0.00 0.44 -0.36 0.89 0.72 -0.13 -0.19 0.70 0.10 0.64 0.14 0.26 -0.09
3913 || orf19.1360.1 || || || Putative adhesin-like protein || 1 1.88 1.87 0.62 0.42 1.27 -0.10 1.66 1.78 0.05 0.24 1.58 -0.06 1.62 0.34 1.06 -0.00
3914 || orf19.7473 || || || Ortholog(s) have role in endocytosis and actin cortical patch, cellular bud neck, cytoplasm localization || 1 1.21 1.27 0.35 0.50 0.60 -0.56 0.94 0.88 -0.18 -0.11 0.79 -0.35 1.12 0.39 0.86 -0.25
3915 || orf19.2598 || VMA4 || || H+ transporting ATPase E chain; transcript regulated by Mig1; caspofungin repressed; protein level decreases in stationary phase cultures; rat catheter biofilm repressed || 1 0.72 0.68 0.14 0.16 -0.01 -0.16 0.51 0.38 0.18 -0.04 0.56 -0.09 0.66 0.17 0.27 0.04
3916 || orf19.4715 || || || Ortholog(s) have tubulin binding activity, role in microtubule cytoskeleton organization, mitochondrial fission, mitochondrion inheritance, nuclear migration along microtubule and cell cortex, cellular bud tip, mitochondrion localization || 1 0.76 0.81 0.46 0.26 0.04 -0.57 0.39 0.67 0.15 0.36 0.68 0.01 0.71 0.19 0.37 -0.21
3917 || orf19.242.2 || || || Ortholog(s) have endoplasmic reticulum localization || 1 0.89 0.95 0.67 0.62 0.00 -0.79 0.51 0.90 -0.01 0.29 0.92 0.23 1.03 0.16 0.34 0.25
3918 || orf19.4715 || || || Ortholog(s) have tubulin binding activity, role in microtubule cytoskeleton organization, mitochondrial fission, mitochondrion inheritance, nuclear migration along microtubule and cell cortex, cellular bud tip, mitochondrion localization || 1 1.01 0.92 0.71 0.40 -0.11 -0.68 0.74 0.69 -0.48 -0.06 0.85 -0.07 0.82 0.09 0.37 0.08
3919 || orf19.1715 || IRO1 || || Putative transcription factor; role in iron utilization, pathogenesis; both IRO1 and adjacent URA3 are mutated in strain CAI4; suppresses S. cerevisiae aft1 mutant low-iron growth defect; hyphal-induced; reports differ about iron regulation || 1 0.79 1.01 0.64 0.50 0.15 -0.58 1.20 0.90 1.09 0.83 0.33 -0.08 0.94 0.33 0.07 0.89
3920 || orf19.1715 || IRO1 || || Putative transcription factor; role in iron utilization, pathogenesis; both IRO1 and adjacent URA3 are mutated in strain CAI4; suppresses S. cerevisiae aft1 mutant low-iron growth defect; hyphal-induced; reports differ about iron regulation || 1 0.99 1.03 0.48 0.68 0.03 -0.44 0.93 1.02 0.68 0.61 0.43 0.07 0.79 0.11 0.26 0.88
3921 || orf19.7548 || MED21 || || Ortholog(s) have RNA polymerase II repressing transcription factor binding, RNA polymerase II transcription coactivator activity, RNA polymerase II transcription corepressor activity || 1 1.18 0.92 -0.02 0.63 -0.19 0.15 1.13 1.07 0.44 0.90 0.26 0.27 1.01 0.36 0.14 0.18
3922 || orf19.6414 || || || Ortholog of C. dubliniensis CD36 : Cd36_34040, C. parapsilosis CDC317 : CPAR2_205850, Candida tenuis NRRL Y-1498 : CANTEDRAFT_132607 and Debaryomyces hansenii CBS767 : DEHA2A11638g || 1 1.04 0.57 0.78 0.91 -0.07 -0.19 0.66 0.49 0.73 0.68 0.30 -0.24 0.48 0.09 -0.05 -0.27
3923 || orf19.1625 || || || Putative ubiquinone oxidoreductase; repressed by nitric oxide; Hap43p-repressed || 1 1.49 1.48 0.85 0.68 0.25 -0.07 1.09 1.26 0.61 0.80 0.56 -0.18 0.67 -0.00 0.30 -0.82
3924 || orf19.4490.2 || QCR8 || || Putative ubiquinol cytochrome c reductase; macrophage and pseudohyphal-induced protein; colony morphology-related gene regulation by Ssn6; Hap43-repressed; Spider biofilm repressed || 1 1.66 1.27 1.29 1.32 0.65 0.21 1.57 1.54 1.11 0.50 0.49 -0.06 0.80 -0.06 0.20 -0.30
3925 || orf19.4490.2 || QCR8 || || Putative ubiquinol cytochrome c reductase; macrophage and pseudohyphal-induced protein; colony morphology-related gene regulation by Ssn6; Hap43-repressed; Spider biofilm repressed || 1 1.62 1.63 1.21 1.33 0.55 0.11 1.54 1.61 1.17 0.72 0.52 0.00 1.16 0.11 0.01 -0.11
3926 || orf19.4490.2 || QCR8 || || Putative ubiquinol cytochrome c reductase; macrophage and pseudohyphal-induced protein; colony morphology-related gene regulation by Ssn6; Hap43-repressed; Spider biofilm repressed || 1 1.52 1.51 1.12 1.38 0.38 -0.00 1.40 1.66 1.16 0.66 0.48 0.11 1.12 0.33 -0.01 -0.37
3927 || orf19.4490.2 || QCR8 || || Putative ubiquinol cytochrome c reductase; macrophage and pseudohyphal-induced protein; colony morphology-related gene regulation by Ssn6; Hap43-repressed; Spider biofilm repressed || 1 1.36 1.55 1.19 1.32 0.36 0.00 1.45 1.62 1.29 0.70 0.34 -0.21 1.00 -0.16 -0.25 -0.74
3928 || orf19.4490.2 || QCR8 || || Putative ubiquinol cytochrome c reductase; macrophage and pseudohyphal-induced protein; colony morphology-related gene regulation by Ssn6; Hap43-repressed; Spider biofilm repressed || 1 1.34 1.38 0.75 0.79 -0.05 -0.12 1.58 1.59 0.67 0.52 0.38 -0.03 0.88 0.17 -0.09 -0.05
3929 || orf19.4294 || || || Ortholog(s) have oxidoreductase activity, role in cytochrome c-heme linkage, mitochondrial membrane organization and extrinsic to mitochondrial inner membrane localization || 1 0.65 0.80 0.23 0.28 -0.05 0.07 0.56 0.90 0.69 0.46 -0.05 -0.05 0.33 0.03 0.03 0.08
3930 || orf19.227 || COX7 || || Putative cytochrome c oxidase; flucytosine induced; repressed by nitric oxide || 1 0.98 1.03 0.51 0.33 0.08 0.38 1.20 1.43 1.24 0.55 0.82 0.43 0.79 0.65 -0.13 0.25
3931 || orf19.29 || || || Ortholog of S. cerevisiae Tah11, a DNA replication licensing factor required for pre-replication complex assembly; rat catheter, flow model and Spider biofilm induced || 1 1.87 1.74 0.67 0.96 0.30 -0.89 1.13 1.43 0.53 1.04 0.24 -0.10 2.04 1.02 -0.05 -0.06
3932 || orf19.2875 || || || Ortholog of S. pombe SPAC1071.09c DNAJ domain protein; Hap43-induced gene || 1 1.78 1.55 0.08 0.26 0.49 -0.14 1.43 1.86 0.39 0.92 0.61 0.24 1.38 1.35 -0.22 -0.41
3933 || orf19.2875 || || || Ortholog of S. pombe SPAC1071.09c DNAJ domain protein; Hap43-induced gene || 1 1.36 1.71 0.70 0.78 0.26 -0.26 0.98 1.72 0.66 1.24 0.74 0.74 1.10 1.55 -0.11 0.02
3934 || orf19.7271 || || || Protein of unknown function; transcript detected on high-resolution tiling arrays || 1 0.57 0.61 0.10 0.21 0.26 0.35 0.60 0.27 0.30 0.16 0.31 0.29 0.41 0.50 0.28 -0.05
3935 || orf19.5001 || CUP2 || || Putative copper-binding transcription factor; required for normal resistance to copper; activates transcription of metallothionein genes; Hap43-repressed; Spider biofilm induced || 1 0.86 1.02 0.47 0.09 0.78 0.49 1.15 0.61 0.76 0.41 0.56 0.56 1.35 0.99 0.91 0.44
3936 || orf19.928 || || || Ortholog of C. dubliniensis CD36 : Cd36_50610, C. parapsilosis CDC317 : CPAR2_303690, Candida tenuis NRRL Y-1498 : CANTEDRAFT_93989 and Debaryomyces hansenii CBS767 : DEHA2E15400g || 1 0.84 0.94 0.47 0.30 0.66 0.21 1.04 0.59 0.73 0.45 0.22 0.38 1.00 0.69 0.99 0.09
3937 || orf19.3154 || || || Ortholog(s) have mitochondrial membrane localization || 1 1.72 1.14 0.40 0.76 0.68 0.36 1.44 1.39 1.59 1.01 0.80 0.46 0.94 1.24 0.75 0.25
3938 || orf19.4918 || || || Has domain(s) with predicted DNA binding activity || 1 0.91 0.91 0.16 0.32 0.21 -0.14 0.99 0.87 0.72 0.65 0.16 0.27 0.93 1.19 0.62 0.41
3939 || orf19.1140 || || || Protein of unknown function; Spider biofilm repressed || 1 0.71 0.77 0.54 0.29 0.36 -0.17 0.60 0.81 0.79 0.66 0.56 0.28 0.89 1.05 0.59 0.18
3940 || orf19.529 || || || Ortholog of C. dubliniensis CD36 : Cd36_29750, C. parapsilosis CDC317 : CPAR2_205260, Candida tenuis NRRL Y-1498 : CANTEDRAFT_91782 and Debaryomyces hansenii CBS767 : DEHA2F19294g || 1 0.50 0.73 0.24 0.04 0.22 -0.19 0.42 0.70 0.64 0.65 0.38 0.19 0.66 0.69 0.23 0.34
3941 || orf19.5041 || || || Ortholog of C. dubliniensis CD36 : Cd36_43600, C. parapsilosis CDC317 : CPAR2_403780, Candida tenuis NRRL Y-1498 : CANTEDRAFT_93767 and Debaryomyces hansenii CBS767 : DEHA2G16984g || 1 0.84 0.99 -0.03 0.03 0.51 -0.22 0.64 0.59 0.47 0.53 0.76 0.32 1.20 0.79 0.66 0.80
3942 || orf19.3505 || || || Ortholog(s) have role in TOR signaling cascade, actin filament bundle assembly, eisosome assembly, endosomal transport, establishment or maintenance of actin cytoskeleton polarity, regulation of cell growth || 1 1.12 0.79 0.33 0.18 0.63 -0.10 1.17 1.17 0.35 0.32 0.77 0.24 1.56 0.98 0.86 0.67
3943 || orf19.954 || || || Putative DnaJ-like chaperone; Hap43-repressed gene || 1 1.14 0.59 0.60 -0.04 0.90 0.27 1.04 1.42 0.91 0.82 0.62 0.18 1.22 0.51 1.26 0.26
3944 || orf19.529 || || || Ortholog of C. dubliniensis CD36 : Cd36_29750, C. parapsilosis CDC317 : CPAR2_205260, Candida tenuis NRRL Y-1498 : CANTEDRAFT_91782 and Debaryomyces hansenii CBS767 : DEHA2F19294g || 1 0.34 0.38 0.36 0.07 -0.00 -0.07 0.67 0.61 0.56 0.69 0.27 0.46 0.86 0.85 0.56 0.47
3945 || orf19.497 || EAF7 || || Subunit of the NuA4 histone acetyltransferase complex || 1 0.31 0.35 0.28 -0.16 0.15 -0.00 0.67 0.58 0.72 0.67 0.41 0.17 0.67 0.63 0.25 0.01
3946 || orf19.3173 || || || Ortholog(s) have Golgi apparatus, endoplasmic reticulum localization || 1 0.19 0.23 0.29 0.07 0.05 0.01 0.54 0.58 0.43 0.48 0.47 0.16 0.34 0.43 0.09 0.22
3947 || orf19.3871 || DAD3 || || Subunit of the Dam1 (DASH) complex, which acts in chromosome segregation by coupling kinetochores to spindle microtubules || 1 0.75 0.71 0.58 0.75 -0.06 -0.14 0.45 1.30 0.41 0.76 0.83 0.46 0.90 1.03 0.27 0.59
3948 || orf19.1484 || || || Ortholog of S, cerevisiae Spc24; a component of the conserved kinetochore-associated Ndc80 complex involved in chromosome segregation, spindle checkpoint activity and kinetochore clustering; Hap43-induced gene || 1 1.22 1.30 1.18 0.72 0.40 -0.17 0.38 1.56 -0.09 0.59 1.35 0.33 1.18 0.68 0.46 0.69
3949 || orf19.4715 || || || Ortholog(s) have tubulin binding activity, role in microtubule cytoskeleton organization, mitochondrial fission, mitochondrion inheritance, nuclear migration along microtubule and cell cortex, cellular bud tip, mitochondrion localization || 1 0.53 0.56 0.75 0.50 0.14 -0.43 0.35 0.55 0.26 0.52 0.75 0.27 0.69 0.39 0.20 0.43
3950 || orf19.6843 || || || Ortholog(s) have role in CENP-A containing nucleosome assembly at centromere, chromatin silencing at centromere, mitotic sister chromatid segregation and nucleoplasm localization || 1 1.00 0.85 0.72 0.66 0.86 -0.28 0.51 1.00 0.51 0.84 1.00 0.60 1.06 0.64 0.14 0.95
3951 || orf19.3714 || || || Ortholog of C. dubliniensis CD36 : Cd36_33530, C. parapsilosis CDC317 : CPAR2_201980, Candida tenuis NRRL Y-1498 : CANTEDRAFT_134293 and Debaryomyces hansenii CBS767 : DEHA2A10164g || 1 0.79 0.70 0.44 0.64 0.60 0.05 0.42 0.72 0.14 0.04 0.68 0.53 1.06 0.82 0.63 0.67
3952 || orf19.6286 || || || Ortholog(s) have role in vacuolar transport and endosome localization || 1 0.58 0.78 0.61 0.40 0.40 -0.30 0.39 0.84 0.40 0.10 0.95 0.70 1.03 0.83 0.51 0.22
3953 || orf19.3625 || || || Has domain(s) with predicted zinc ion binding activity || 1 0.61 0.41 0.86 0.46 0.41 -0.35 0.62 0.64 0.48 0.25 0.60 0.29 0.77 0.58 0.27 0.08
3954 || orf19.1265 || || || Ortholog(s) have Rab guanyl-nucleotide exchange factor activity and role in CVT pathway, early endosome to Golgi transport, intra-Golgi vesicle-mediated transport, macroautophagy, regulation of Rab GTPase activity || 1 0.81 0.66 0.46 0.68 0.52 -0.30 0.50 0.72 0.50 0.74 0.45 0.14 0.69 0.36 0.04 0.12
3955 || orf19.6930 || SOL1 || || Cell cycle regulator; partial functional homolog of S. cerevisiae Sic1p; protein degradation regulated by SCF(CDC4) pathway; CDK phosphorylation predicted || 1 1.11 1.29 0.63 0.86 0.79 -0.32 0.28 1.48 0.36 1.03 1.14 0.41 0.85 0.03 0.21 0.10
3956 || orf19.837.1 || INO4 || || Transcription factor; activator that forms a heterodimer with Ino2; likely regulates genes involved in phosphatidylcholine and phosphatidylinositol biosynthesis, fatty acid beta-oxidation, and peroxisome biogenesis; gene has intron || 1 2.08 2.22 1.22 0.91 0.72 0.19 0.90 1.29 0.90 0.62 0.96 0.50 1.15 0.49 0.99 -0.39
3957 || orf19.1666 || || || Ortholog of Dig2, a MAP kinase-responsive inhibitor of Ste12; regulates mating-specific genes and invasive growth in S. cerevisiae; induced by alpha pheromone in SpiderM medium || 1 1.02 1.22 0.43 0.67 0.30 -0.17 0.94 1.04 0.92 0.77 0.44 -0.03 1.06 0.70 0.10 -0.19
3958 || orf19.5181 || NIK1 || || Histidine kinase involved in a two-component signaling pathway that regulates cell wall biosynthesis; required for wild-type virulence in mouse systemic infection but not for wild-type growth or drug sensitivity/resistance; 9 HAMP domains || 1 0.96 0.98 0.29 0.43 0.22 0.05 1.20 1.28 0.94 0.44 0.58 0.09 1.29 0.82 0.11 -0.36
3959 || orf19.5016 || || || Ortholog(s) have role in cellular response to UV and cytosol, nucleus localization || 1 1.12 1.32 0.53 0.47 0.51 0.27 1.53 1.60 0.71 0.47 0.75 0.19 1.20 0.77 0.77 0.53
3960 || orf19.5016 || || || Ortholog(s) have role in cellular response to UV and cytosol, nucleus localization || 1 1.45 1.67 0.62 0.23 0.44 0.35 1.94 2.07 1.00 0.80 0.90 0.42 1.14 1.28 0.94 0.66
3961 || orf19.2570 || MCI4 || || Putative NADH-ubiquinone dehydrogenase; Hap43p-repressed gene || 1 0.93 0.97 0.79 0.44 0.45 0.23 1.10 1.41 0.73 0.96 0.65 0.14 0.32 0.41 0.55 0.14
3962 || orf19.3611 || || || Protein of unknown function; Hap43-repressed gene; repressed by nitric oxide || 1 0.81 0.78 0.65 0.37 0.06 -0.20 0.93 1.29 0.42 0.69 0.50 0.10 0.36 0.41 0.18 0.05
3963 || orf19.2263 || || || Has domain(s) with predicted adenyl nucleotide binding activity || 1 0.50 0.65 0.62 0.69 0.34 -0.29 0.88 1.30 0.75 0.71 0.80 0.35 0.66 0.57 0.29 0.10
3964 || orf19.6898.1 || || || Ortholog(s) have mitochondrion localization || 1 0.95 1.15 0.85 0.99 0.10 0.08 1.11 1.54 1.16 1.36 0.85 0.33 0.88 1.07 0.15 0.01
3965 || orf19.1389 || || || Ortholog(s) have poly(A) RNA binding activity, role in mRNA metabolic process and cytoplasm localization || 1 0.82 0.86 0.30 0.73 0.04 -0.34 0.97 1.25 0.71 0.82 0.68 0.00 0.75 0.24 0.23 -0.07
3966 || orf19.6114 || || || Protein of unknown function; transcript detected on high-resolution tiling arrays || 1 2.02 1.98 1.49 1.60 0.42 0.37 2.63 2.64 2.04 1.78 1.72 -0.18 2.94 1.99 1.40 0.30
3967 || orf19.6414.3 || TPM2 || || Putative tropomyosin isoform 2; regulated by Gcn4; repressed by amino acid starvation; macrophage-induced; protein levels decrease in stationary cells; Hap43-induced; rat catheter and Spider biofilm repressed || 1 2.12 2.09 1.10 1.08 0.40 -0.08 2.04 1.83 1.22 1.51 1.80 0.81 1.96 1.14 1.23 1.01
3968 || orf19.1389 || || || Ortholog(s) have poly(A) RNA binding activity, role in mRNA metabolic process and cytoplasm localization || 1 0.82 0.95 0.51 0.66 0.53 -0.05 0.69 0.92 0.74 0.82 0.58 0.10 0.80 0.53 0.46 0.12
3969 || orf19.652 || || || Ortholog(s) have crossover junction endodeoxyribonuclease activity, role in DNA repair and cytoplasm, nucleus localization || 1 1.19 1.33 0.84 0.87 0.79 0.10 1.11 0.87 0.67 0.67 0.79 0.09 1.11 0.37 0.87 0.10
3970 || orf19.2598 || VMA4 || || H+ transporting ATPase E chain; transcript regulated by Mig1; caspofungin repressed; protein level decreases in stationary phase cultures; rat catheter biofilm repressed || 1 1.05 0.99 0.89 0.94 0.37 0.19 0.85 1.08 0.75 0.38 0.92 0.46 1.09 0.46 0.55 0.02
3971 || orf19.330.1 || RUB1 || || Ubiquitin-related protein with similarity to mammalian NEDD8; reversible conjugation (neddylation) of the cullin subunit (Cdc53p) modulates the ubiquitin ligase activity of the SCF complexes || 1 0.85 0.97 0.54 0.45 0.44 0.14 0.84 1.06 0.46 0.51 0.80 0.36 0.48 0.51 0.41 -0.19
3972 || orf19.3844 || MRP8 || || Mitochondrial ribosomal protein; ortholog of S. cerevisiae Mrp8; transcript induced in hyphal form; mutant is viable; flow model and rat catheter biofilm repressed || 1 1.08 1.21 0.45 0.15 0.37 -0.37 1.11 1.29 0.62 0.54 0.91 -0.01 0.62 0.50 0.18 -0.14
3973 || orf19.6898.1 || || || Ortholog(s) have mitochondrion localization || 1 2.60 2.18 0.77 1.19 0.52 -0.09 2.66 3.15 1.42 1.53 2.05 0.21 1.56 0.85 1.27 0.06
3974 || orf19.446.1 || || || Protein with a NADH-ubiquinone oxidoreductase B18 subunit domain; gene has intron || 1 1.39 1.50 0.36 0.37 0.40 -0.40 1.96 2.02 0.50 0.86 2.00 0.57 1.12 0.53 1.02 -0.02
3975 || orf19.4427 || SKP1 || || Putative subunit D of kinetochore protein complex CBF3; regulated by Gcn4p; repressed in response to amino acid starvation (3-aminotriazole treatment) || 1 0.94 0.94 0.27 0.25 0.41 -0.22 1.15 1.13 0.20 0.39 0.92 0.00 0.86 0.36 0.41 -0.11
3976 || orf19.4427 || SKP1 || || Putative subunit D of kinetochore protein complex CBF3; regulated by Gcn4p; repressed in response to amino acid starvation (3-aminotriazole treatment) || 1 1.07 1.03 0.31 0.31 0.62 -0.04 1.25 1.30 0.33 0.26 1.14 0.46 0.98 0.60 0.71 0.01
3977 || orf19.3235 || || || Putative F-actin capping protein subunit alpha; possibly an essential gene, disruptants not obtained by UAU1 method || 1 1.09 1.04 0.15 0.34 0.25 -0.37 1.41 1.55 0.69 0.62 1.43 0.81 1.05 0.89 0.69 0.29
3978 || orf19.1140 || || || Protein of unknown function; Spider biofilm repressed || 1 1.25 1.33 0.17 0.34 -0.33 -0.54 1.18 1.25 0.34 0.45 0.97 0.20 0.86 0.84 0.56 0.21
3979 || orf19.6414.3 || TPM2 || || Putative tropomyosin isoform 2; regulated by Gcn4; repressed by amino acid starvation; macrophage-induced; protein levels decrease in stationary cells; Hap43-induced; rat catheter and Spider biofilm repressed || 1 1.76 1.89 0.27 0.54 -0.06 -0.74 1.81 1.54 0.44 0.62 1.56 0.22 1.38 0.36 0.77 0.50
3980 || orf19.1625 || || || Putative ubiquinone oxidoreductase; repressed by nitric oxide; Hap43p-repressed || 1 2.09 2.08 0.95 0.98 0.53 0.52 1.44 1.44 0.79 1.05 1.38 0.57 0.74 0.45 1.20 0.26
3981 || orf19.5077 || || || Protein of unknown function; Hap43-repressed gene; repressed by nitric oxide || 1 1.67 1.73 0.54 0.36 0.65 0.74 1.45 1.74 0.84 0.85 1.26 0.50 0.96 0.03 0.90 0.10
3982 || orf19.5547 || || || Protein of unknown function; Hap43-repressed gene || 1 1.97 2.00 0.56 0.47 0.50 0.37 1.53 1.76 0.43 0.77 1.27 0.17 0.83 -0.04 1.01 0.27
3983 || orf19.5547 || || || Protein of unknown function; Hap43-repressed gene || 1 2.29 2.45 0.34 0.31 0.89 0.28 1.96 2.12 0.63 0.70 1.68 0.32 1.19 -0.04 1.31 0.12
3984 || orf19.6132 || || || Ortholog of C. dubliniensis CD36 : Cd36_33000, C. parapsilosis CDC317 : CPAR2_701740, Candida tenuis NRRL Y-1498 : CANTEDRAFT_93887 and Debaryomyces hansenii CBS767 : DEHA2E04554g || 1 0.95 0.98 0.39 0.23 0.51 0.03 0.63 0.80 0.29 0.27 0.35 -0.10 0.52 0.14 0.70 -0.04
3985 || orf19.1203.1 || || || Predicted dolichol-phosphate mannosyltransferase subunit; flow model and Spider biofilm repressed || 1 1.37 1.42 1.24 1.13 0.48 -0.28 1.14 1.12 0.48 0.59 0.70 0.31 0.91 0.19 0.53 0.42
3986 || orf19.4009 || CNB1 || || Regulatory subunit of calcineurin B (Ca[2+]-calmodulin-regulated S/T protein phosphatase); required for wild-type resistance to fluconazole or to SDS; micafungin is fungicidal to null mutant || 1 0.67 0.66 0.56 0.76 0.01 -0.10 0.41 0.68 0.20 0.40 0.48 0.36 0.35 0.21 0.41 0.49
3987 || orf19.3140.1 || || || Ortholog(s) have role in cellular response to DNA damage stimulus, proteasome assembly, ubiquitin-dependent protein catabolic process and cytosol, nucleus localization || 1 1.09 1.22 1.02 1.14 0.17 0.19 0.75 1.18 0.40 0.49 1.05 0.52 0.50 0.41 0.81 0.69
3988 || orf19.7335 || PRE8 || || Putative alpha-2_sc subunit of proteasome; macrophage-induced protein; regulated by Gcn2p and Gcn4p; transcription is positively regulated by Tbf1p; stationary phase enriched protein || 1 0.76 0.78 0.77 0.85 0.41 0.41 0.56 0.97 0.19 0.53 0.72 0.53 0.52 0.34 0.77 0.56
3989 || orf19.6551.1 || STE18 || || Protein similar to S. cerevisiae Ste18p; expressed in opaque or white MTLa/MTLa or MTLalpha/MTLalpha, but not MTLa/MTLalpha cells; MTLa1p, MTLalpha2p bind promoter region || 1 1.72 1.62 1.57 1.85 0.81 0.75 0.94 1.80 0.48 0.63 1.69 0.64 0.66 0.30 0.83 0.36
3990 || orf19.3963 || || || Ortholog(s) have mitochondrion localization || 1 0.87 0.86 0.40 0.64 0.29 0.26 0.41 1.05 0.16 0.35 0.62 0.24 0.56 0.22 0.62 0.30
3991 || orf19.3843 || || || Ortholog(s) have role in filamentous growth, posttranslational protein targeting to membrane, translocation and Sec62/Sec63 complex localization || 1 0.75 0.81 0.64 0.75 0.34 -0.11 0.73 1.02 0.32 0.67 0.95 0.54 0.47 0.46 0.65 0.07
3992 || orf19.4600.1 || || || Protein of unknown function; flow model biofilm repressed || 1 0.87 1.02 1.13 1.15 0.43 0.04 0.88 1.44 0.85 0.95 1.18 0.72 0.68 0.62 0.22 0.46
3993 || orf19.4600.1 || || || Protein of unknown function; flow model biofilm repressed || 1 0.80 1.17 1.01 1.30 0.29 -0.04 0.84 1.66 0.72 0.89 1.48 0.58 0.49 0.33 0.18 0.52
3994 || orf19.4600.1 || || || Protein of unknown function; flow model biofilm repressed || 1 1.38 1.32 0.99 1.20 0.23 -0.17 1.40 2.10 0.59 0.98 1.76 0.68 0.67 0.27 0.57 0.75
3995 || orf19.4600.1 || || || Protein of unknown function; flow model biofilm repressed || 1 1.50 1.68 1.05 1.25 0.50 -0.10 1.45 2.19 0.75 0.93 1.81 0.76 0.93 0.43 0.56 0.42
3996 || orf19.4600.1 || || || Protein of unknown function; flow model biofilm repressed || 1 1.27 1.26 0.89 1.01 0.32 -0.09 1.36 1.68 0.85 0.87 1.67 0.32 0.94 0.14 0.32 0.12
3997 || orf19.3140.1 || || || Ortholog(s) have role in cellular response to DNA damage stimulus, proteasome assembly, ubiquitin-dependent protein catabolic process and cytosol, nucleus localization || 1 1.13 1.15 0.56 0.48 0.40 0.01 0.95 1.24 0.31 0.41 1.01 0.46 0.77 0.38 1.01 0.77
3998 || orf19.2630 || RAD59 || || Protein involved in homologous recombination and DNA breaks repair; similar to S. cerevisiae Rad59p; N-terminal similarity with Rad52p || 1 1.19 1.56 0.68 0.78 0.14 0.08 0.77 0.91 0.20 0.55 0.65 0.18 0.63 0.82 0.39 0.36
3999 || orf19.6008 || || || S. cerevisiae ortholog YLL032C interacts with ribosomes; repressed by alpha pheromone in SpiderM medium || 1 2.91 3.11 1.21 2.53 0.04 -0.65 1.85 2.42 0.89 1.16 1.21 -0.06 1.85 0.98 0.89 0.11
4000 || orf19.6008 || || || S. cerevisiae ortholog YLL032C interacts with ribosomes; repressed by alpha pheromone in SpiderM medium || 1 1.96 2.11 0.98 1.95 -0.34 -0.80 1.22 1.65 0.62 1.20 0.91 -0.06 1.57 1.27 0.44 0.10
4001 || orf19.6607 || || || Ortholog(s) have role in mitochondrial respiratory chain complex I assembly and mitochondrial membrane localization || 1 1.18 1.00 0.40 0.52 -0.43 -0.35 0.91 1.47 0.43 0.44 0.56 0.12 0.69 0.21 -0.02 0.20
4002 || orf19.6509 || || || Ortholog(s) have role in cellular response to zinc ion and cytosol, nucleus localization || 1 1.49 1.42 0.71 0.74 -0.31 -0.35 1.01 1.43 0.53 0.34 1.15 0.23 1.11 0.08 0.22 0.25
4003 || orf19.1203.1 || || || Predicted dolichol-phosphate mannosyltransferase subunit; flow model and Spider biofilm repressed || 1 1.62 1.48 1.01 1.04 -0.45 -0.60 0.77 1.30 0.19 0.63 0.90 0.07 0.69 -0.06 -0.38 0.22
4004 || orf19.3844 || MRP8 || || Mitochondrial ribosomal protein; ortholog of S. cerevisiae Mrp8; transcript induced in hyphal form; mutant is viable; flow model and rat catheter biofilm repressed || 1 1.25 1.28 0.50 0.29 0.17 -0.18 0.92 1.20 0.35 0.41 0.67 0.26 0.27 0.37 0.02 0.01
4005 || orf19.2512 || || || Ortholog of C. dubliniensis CD36 : Cd36_81000, C. parapsilosis CDC317 : CPAR2_103050, Candida tenuis NRRL Y-1498 : CANTEDRAFT_116326 and Debaryomyces hansenii CBS767 : DEHA2G01958g || 1 1.28 1.48 0.70 1.18 0.28 0.69 1.17 1.97 0.90 0.14 1.00 0.57 0.93 0.48 0.19 0.55
4006 || orf19.7271 || || || Protein of unknown function; transcript detected on high-resolution tiling arrays || 1 0.95 0.81 0.66 0.72 -0.09 0.45 0.77 0.69 0.71 0.44 0.23 0.09 0.70 0.66 0.26 0.17
4007 || orf19.3821 || || || Ortholog of C. dubliniensis CD36 : Cd36_44290, C. parapsilosis CDC317 : CPAR2_500740, Candida tenuis NRRL Y-1498 : CANTEDRAFT_137302 and Debaryomyces hansenii CBS767 : DEHA2F07326g || 1 1.73 1.77 1.10 0.78 1.05 0.77 1.31 1.23 1.09 0.65 0.34 0.04 1.61 1.26 0.55 0.23
4008 || orf19.7519 || || || Ortholog of C. dubliniensis CD36 : Cd36_25180, C. parapsilosis CDC317 : CPAR2_800030, Candida tenuis NRRL Y-1498 : CANTEDRAFT_125790 and Debaryomyces hansenii CBS767 : DEHA2E18260g || 1 1.55 1.70 0.96 0.90 0.30 0.33 1.25 1.32 0.60 0.52 0.39 -0.31 1.15 1.14 0.45 -0.10
4009 || orf19.7519 || || || Ortholog of C. dubliniensis CD36 : Cd36_25180, C. parapsilosis CDC317 : CPAR2_800030, Candida tenuis NRRL Y-1498 : CANTEDRAFT_125790 and Debaryomyces hansenii CBS767 : DEHA2E18260g || 1 1.55 1.61 0.47 1.35 0.60 0.25 1.11 1.16 1.05 0.68 0.23 -0.34 1.25 0.94 0.21 0.03
4010 || orf19.4918 || || || Has domain(s) with predicted DNA binding activity || 1 0.86 1.43 0.88 1.07 0.35 0.36 0.26 0.94 0.56 0.16 0.19 -0.15 0.67 0.71 0.44 0.38
4011 || orf19.2512 || || || Ortholog of C. dubliniensis CD36 : Cd36_81000, C. parapsilosis CDC317 : CPAR2_103050, Candida tenuis NRRL Y-1498 : CANTEDRAFT_116326 and Debaryomyces hansenii CBS767 : DEHA2G01958g || 1 0.56 0.56 0.08 0.29 -0.04 0.15 0.63 0.76 0.18 -0.19 0.31 0.09 0.51 0.26 0.19 0.18
4012 || orf19.2078 || || || Ortholog(s) have role in Golgi to vacuole transport and AP-1 adaptor complex localization || 1 0.36 0.63 0.36 0.25 0.44 -0.20 0.51 0.74 0.53 0.01 0.43 0.15 0.41 0.45 0.30 0.56
4013 || orf19.5618 || || || Ortholog(s) have SNARE binding, unfolded protein binding activity || 1 1.72 1.32 0.09 0.98 0.49 0.26 0.40 0.96 0.75 0.44 0.69 0.79 0.32 0.66 0.86 0.68
4014 || orf19.6009 || SET1 || || Lysine histone methyltransferase; methylates histone H3 K4; regulates of white-opaque switch, epithelial cell adhesion, agar-embedded filamentation, virulence in mice; unique N-terminus immunogenic in human; rat catheter biofilm repressed || 1 0.47 0.61 0.30 0.42 0.57 0.27 0.21 0.58 -0.06 0.03 0.54 0.73 0.75 0.41 0.51 0.03
4015 || orf19.2827 || || || Ortholog(s) have structural constituent of cytoskeleton activity || 1 1.02 1.12 0.46 0.38 0.44 0.45 0.26 0.92 -0.32 -0.29 1.15 0.99 1.49 0.67 0.56 0.65
4016 || orf19.2827 || || || Ortholog(s) have structural constituent of cytoskeleton activity || 1 0.85 0.76 0.05 0.10 0.26 0.08 0.45 0.83 -0.25 -0.01 1.00 0.43 1.47 0.32 0.62 0.79
4017 || orf19.7290 || || || Ortholog(s) have RNA cap binding activity, role in deadenylation-dependent decapping of nuclear-transcribed mRNA and cytoplasmic mRNA processing body, cytosol, mRNA cap binding complex, nucleus localization || 1 0.70 0.52 0.40 0.52 -0.11 -0.04 0.25 0.90 -0.17 0.55 1.18 0.64 0.95 0.46 0.56 0.16
4018 || orf19.5875 || VAM3 || || Predicted target membrane receptor (t-SNARE) involved in vacuolar transport, endocytosis, and secretion; required for biofilm formation in RPMI-1640 and for virulence; rat catheter biofilm repressed || 1 0.67 1.00 -0.15 0.29 0.86 0.22 0.22 1.47 0.14 0.67 0.42 0.69 0.27 0.44 0.84 0.32
4019 || orf19.3976 || || || Ortholog(s) have structural constituent of cytoskeleton activity, role in establishment of mitotic spindle orientation, nuclear migration and astral microtubule, cell cortex, dynactin complex, spindle pole body localization || 1 0.83 0.65 0.13 0.07 0.38 0.31 0.32 0.67 -0.12 0.68 0.71 0.28 0.28 0.03 0.54 0.40
4020 || orf19.4443 || YPD1 || || Phosphohistidine intermediate protein in a phosphorelay signal transduction pathway; residue His69 is the phosphoacceptor histidine; predicted to be soluble and cytosolic; functional homolog of S. cerevisiae Ypd1p || 1 0.77 0.79 0.22 0.22 0.75 0.24 0.24 0.64 0.19 0.60 1.03 0.72 -0.03 0.07 0.43 0.17
4021 || orf19.4443 || YPD1 || || Phosphohistidine intermediate protein in a phosphorelay signal transduction pathway; residue His69 is the phosphoacceptor histidine; predicted to be soluble and cytosolic; functional homolog of S. cerevisiae Ypd1p || 1 0.81 1.01 -0.22 -0.09 1.09 0.07 0.40 0.81 0.18 0.62 1.50 0.74 -0.14 0.20 0.70 0.47
4022 || orf19.692 || || || Protein of unknown function; Hap43-repressed gene; rat catheter and Spider biofilm induced || 1 0.70 0.87 0.31 0.09 0.78 -0.09 0.69 0.26 0.37 0.57 0.98 0.09 0.64 -0.25 1.23 0.75
4023 || orf19.1658 || || || Ortholog(s) have cell cortex, cellular bud neck, cellular bud tip, mating projection tip localization || 1 0.61 0.54 0.26 0.25 0.62 -0.18 0.15 0.15 0.15 0.21 0.64 0.50 0.71 -0.06 0.88 0.38
4024 || orf19.4961 || STP2 || || Amino-acid-regulated transcription factor; activates transcription of amino acid permease genes; activated by amino-acid-induced proteolytic processing (Ssy1, Csh3 dependent); required for alkalinization of medium; Spider biofilm induced || 1 0.69 0.70 0.38 0.15 0.76 0.46 0.45 0.13 0.12 0.15 0.63 0.16 1.14 0.33 1.32 0.80
4025 || orf19.761 || TCO89 || || Putative homolog of S. cerevisiae Tco89p, which is a component of the TOR C1 complex that is involved in the regulation of growth and cell wall integrity; heterozygous null mutant displays sensitivity to rapamycin || 1 0.39 0.25 0.41 0.22 0.38 0.10 0.22 0.06 0.16 0.05 0.36 0.07 0.28 0.30 0.73 0.33
4026 || orf19.6981 || || || Ortholog of S. cerevisiae : YKR051W, C. glabrata CBS138 : CAGL0K08228g, C. dubliniensis CD36 : Cd36_85420, C. parapsilosis CDC317 : CPAR2_405720 and Candida tenuis NRRL Y-1498 : CANTEDRAFT_124861 || 1 0.47 0.54 0.38 0.47 0.58 0.20 0.07 -0.02 0.03 0.04 0.25 0.28 0.36 0.21 0.89 0.60
4027 || orf19.738 || MYO5 || || Class I myosin; nonessential; role in cortical actin patch polarity and polar budding; required for hyphal growth, white-opaque switch; regulatory phosphorylation on S366; downregulated on adherence to polystyrene || 1 0.57 0.75 0.47 0.47 0.94 0.48 0.43 0.12 0.46 -0.32 0.33 0.25 0.70 0.16 0.73 0.52
4028 || orf19.1201 || || || Ortholog(s) have serine-tRNA ligase activity, role in invasive growth in response to glucose limitation, mitochondrial seryl-tRNA aminoacylation, pseudohyphal growth, spore germination and mitochondrion localization || 1 0.59 0.80 0.42 0.18 0.99 0.50 0.27 0.03 0.73 -0.12 0.31 0.28 1.03 0.16 0.43 0.99
4029 || orf19.6980 || || || Has domain(s) with predicted ATP binding, protein tyrosine kinase activity and role in protein phosphorylation || 1 1.13 1.25 0.79 0.47 0.69 0.04 0.45 0.25 0.79 0.28 0.69 0.73 0.20 -0.21 0.71 0.37
4030 || orf19.866 || RAD32 || || Protein similar to S. cerevisiae protein with role in nucleotide excision repair; down-regulation associated with azole resistance; Hap43p-repressed gene || 1 0.69 0.99 0.41 0.09 0.56 0.25 0.32 0.31 1.04 0.27 0.96 0.80 0.63 -0.31 0.28 1.11
4031 || orf19.1196 || PKH3 || || Ortholog(s) have protein kinase activity and role in MAPK cascade involved in cell wall biogenesis, protein phosphorylation || 1 0.17 0.40 0.56 0.18 0.54 0.17 0.24 0.20 0.35 0.00 0.40 0.49 0.71 0.04 0.12 0.27
4032 || orf19.2507 || ARP9 || || Protein similar to S. cerevisiae Arp3p, a component of the Arp2/3 complex involved in actin-dependent processes; likely to be essential for growth, based on an insertional mutagenesis strategy || 1 0.40 0.32 0.66 0.38 0.39 -0.15 0.27 0.37 0.22 0.05 0.40 0.79 0.49 -0.06 0.22 0.32
4033 || orf19.5490 || || || Predicted ORF in Assemblies 19, 20 and 21; merged with orf19.5489 in Assembly 21 || 1 0.21 0.20 0.81 -0.09 0.32 -0.15 0.28 0.61 0.36 0.47 0.65 0.38 0.71 -0.06 0.68 0.38
4034 || orf19.6598 || WAL1 || || Protein required for hyphal growth and for wild-type cell morphology, polarized budding, endocytosis, vacuole morphology; similar to Wiskott-Aldrich syndrome protein; localizes to cortical actin patches and hyphal tips || 1 -0.00 0.08 0.60 0.34 0.26 0.17 0.38 0.55 0.28 0.24 0.45 0.33 0.35 -0.05 0.58 0.56
4035 || orf19.4685 || || || Dubious open reading frame || 1 -0.14 0.46 0.63 0.05 0.22 0.55 0.44 0.99 0.77 0.38 0.96 0.46 0.67 0.14 0.68 0.22
4036 || orf19.2067 || || || Protein with a predicted role in mitochondrial iron metabolism; Hap43-repressed; expression upregulated during growth in the mouse cecum; Spider biofilm induced || 1 0.31 0.51 0.51 0.62 0.39 0.75 0.40 0.18 0.51 0.52 0.75 0.50 0.10 -0.59 0.68 -0.27
4037 || orf19.7378 || || || Ortholog(s) have phosphopantothenoylcysteine decarboxylase activity, protein phosphatase inhibitor activity and role in regulation of mitotic cell cycle, response to salt stress || 1 0.40 0.36 0.53 0.34 0.47 0.58 0.08 0.25 -0.03 0.05 0.52 0.48 0.34 -0.44 0.64 -0.13
4038 || orf19.3517 || || || Ortholog(s) have Dsc E3 ubiquitin ligase complex, endoplasmic reticulum, fungal-type vacuole lumen localization || 1 0.63 0.70 0.63 0.62 0.42 0.39 -0.00 0.26 0.37 0.14 0.80 0.40 0.38 -0.32 0.70 0.05
4039 || orf19.808 || || || Ortholog(s) have role in histone deacetylation, negative regulation of chromatin silencing at rDNA and negative regulation of chromatin silencing at silent mating-type cassette, more || 1 0.51 0.54 0.51 0.69 0.88 0.67 0.16 0.54 0.50 0.12 0.85 0.33 0.47 0.53 -0.17
4040 || orf19.1506 || || || Ortholog of Candida albicans WO-1 : CAWG_03962 || 1 0.69 0.54 0.28 0.66 0.76 1.00 -0.17 0.71 0.27 0.62 1.15 0.38 0.55 0.56 0.03
4041 || orf19.3116 || EXM2 || || Putative U1 snRNP complex compotent; decreased transcription is observed upon fluphenazine treatment || 1 0.31 0.24 0.04 0.11 0.31 0.12 0.05 0.08 -0.15 -0.08 0.36 0.09 0.14 0.04 0.17 -0.18
4042 || orf19.3907 || || || Ortholog of Candida albicans WO-1 : CAWG_04797 || 1 0.92 0.86 0.28 0.72 0.74 0.30 0.42 0.36 -0.17 0.61 1.21 0.08 0.66 1.05 -0.73
4043 || orf19.1722 || || || Ortholog of Candida albicans WO-1 : CAWG_02462 || 1 1.30 1.06 0.27 1.45 0.24 0.56 -0.42 0.36 1.31 -0.03 0.59 -0.58 0.52
4044 || orf19.7436.1 || ECM15 || || Protein of unknown function; predicted role in cell wall organization; Hap43-repressed; caspofungin repressed; Spider biofilm induced; rat catheter biofilm repressed || 1 1.08 0.97 0.71 0.52 0.94 0.62 0.66 0.58 0.33 -0.30 0.57 -0.19 0.43 -0.49 0.21 0.03
4045 || orf19.7436.1 || ECM15 || || Protein of unknown function; predicted role in cell wall organization; Hap43-repressed; caspofungin repressed; Spider biofilm induced; rat catheter biofilm repressed || 1 0.98 0.94 0.41 0.48 1.08 0.56 0.87 0.46 0.12 -0.26 0.63 -0.03 0.17 -0.34 0.65 -0.28
4046 || orf19.7501 || || || Nucleosome assembly protein; protein present in exponential and stationary growth phase yeast cultures || 1 1.41 1.54 0.55 0.56 1.48 0.74 0.78 0.76 -0.31 0.12 0.86 0.15 0.59 -0.15 0.47 0.09
4047 || orf19.6667 || || || Predicted histone deacetylase activity; Spider biofilm induced || 1 1.22 0.81 0.58 0.61 1.09 0.93 1.38 0.93 -0.57 -0.44 1.79 0.44 0.39 -0.72 1.23 0.81
4048 || orf19.6455 || || || Protein of unknown function, transcript is upregulated in clinical isolates from HIV+ patients with oral candidiasis || 1 0.86 0.39 0.08 0.19 0.84 0.70 0.54 0.44 -0.20 0.08 0.82 0.21 0.39 -0.15 0.79 0.12
4049 || orf19.7183 || || || Ortholog(s) have role in protein folding in endoplasmic reticulum and ER membrane protein complex localization || 1 0.53 0.62 -0.05 -0.01 0.72 0.42 0.35 0.57 -0.17 -0.23 0.89 -0.08 0.41 -0.37 0.81 0.20
4050 || orf19.4323 || || || Ortholog(s) have phosphatidylinositol-3-phosphate binding activity and endosome localization || 1 1.26 0.91 0.39 0.33 0.70 0.41 0.23 0.17 -0.41 -0.09 0.57 0.19 0.49 0.08 0.97 0.22
4051 || orf19.1509 || ROD1 || || Protein similar to S. cerevisiae Rod1;a membrane protein with a role in drug tolerance; repressed by Rgt1; mutant is viable || 1 0.78 0.74 0.52 -0.08 0.40 0.52 0.49 0.13 -0.05 -0.24 0.45 0.16 0.56 0.27 0.47 0.22
4052 || orf19.2533.1 || || || Protein with a predicted role in protein translocation from the endoplasmic reticulum || 1 2.02 2.34 0.96 1.07 1.83 0.36 0.91 1.18 0.37 1.06 1.61 0.28 1.93 -0.20 0.22 0.28
4053 || orf19.7452 || || || Ortholog(s) have chromatin binding activity and role in DNA replication initiation, DNA unwinding involved in DNA replication, double-strand break repair via break-induced replication || 1 0.53 1.00 0.36 0.40 1.20 -0.06 0.36 0.47 0.16 0.31 0.77 0.28 1.34 -0.20 0.32 0.35
4054 || orf19.10712 || MTLALPHA1 || || Master regulator (activator) of alpha mating type; gene of the MTLalpha (Mating Type Like) locus; ortholog of S. cerevisiae Alpha1p; a/alpha mating type may increase virulence, offers competitive advantage || 1 0.41 0.49 0.21 0.02 0.46 0.25 0.17 0.02 0.44 0.58 0.22 0.74 0.11 0.42
4055 || orf19.527 || || || Protein of unknown function; flow model biofilm induced || 1 0.33 0.48 0.15 0.25 0.53 0.31 0.39 0.25 0.39 0.50 0.35 0.20 0.52 0.02 0.30 -0.40
4056 || orf19.4455 || || || Protein of unknown function; Spider biofilm induced || 1 0.65 1.08 0.50 0.28 1.05 1.53 0.70 0.23 0.75 1.00 0.87 0.40 1.16 0.90 0.43 -1.21
4057 || orf19.5905 || || || Protein of unknown function; Hap43-induced; F-12/CO2 early biofilm induced || 1 0.65 0.41 0.64 0.38 0.51 1.03 0.51 0.22 0.67 1.07 0.10 0.58 0.71 0.51 0.16 -0.38
4058 || orf19.5905 || || || Protein of unknown function; Hap43-induced; F-12/CO2 early biofilm induced || 1 0.76 0.79 0.58 0.58 0.52 0.91 1.01 0.71 0.68 1.53 0.27 0.20 1.00 0.44 0.37 -0.47
4059 || orf19.1791 || || || Putative protein with a predicted role in 60S ribosomal subunit biogenesis; Hap43p-induced gene; ortholog of S. cerevisiae MAK11 || 1 0.56 0.56 0.51 0.40 0.31 0.80 0.61 0.60 0.17 1.08 0.56 -0.14 0.75 -0.11 -0.10 -0.25
4060 || orf19.1791 || || || Putative protein with a predicted role in 60S ribosomal subunit biogenesis; Hap43p-induced gene; ortholog of S. cerevisiae MAK11 || 1 0.30 0.51 0.54 0.15 0.39 0.64 0.51 0.57 0.09 1.17 0.64 -0.07 0.63 0.06 0.00 0.03
4061 || orf19.5802 || || || Ortholog(s) have role in maturation of SSU-rRNA and cytoplasm, nucleus localization || 1 0.12 0.23 0.48 0.11 0.61 0.62 0.47 0.22 0.11 1.19 0.51 -0.08 0.91 0.37 0.20 -0.29
4062 || orf19.4125 || PZF1 || || C2H2 transcription factor; Hap43-induced; rat catheter and Spider biofilm induced || 1 0.11 0.39 0.57 -0.07 0.31 0.63 0.45 0.23 0.03 0.93 0.60 0.10 0.61 0.73 -0.14 -0.05
4063 || orf19.3831 || || || Ortholog(s) have telomerase inhibitor activity, role in box C/D snoRNA 3'-end processing, negative regulation of telomere maintenance via telomerase and nucleolus, nucleoplasm localization || 1 0.31 0.76 0.54 0.22 0.44 1.77 1.12 0.25 0.12 1.30 0.48 0.59 1.23 0.56 0.66 0.27
4064 || orf19.1082 || || || Protein with an Alba DNA/RNA-binding protein domain; Spider biofilm induced || 1 0.76 0.89 0.27 0.19 0.72 0.92 0.17 0.87 -0.02 0.89 -0.17 0.16 0.41 0.13 0.27 0.25
4065 || orf19.6776 || GCD2 || || Putative translation initiation factor; genes encoding ribosomal subunits, translation factors, and tRNA synthetases are downregulated upon phagocytosis by murine macrophage || 1 0.29 0.94 0.24 0.14 0.38 0.40 0.22 0.38 0.00 0.58 0.32 0.08 0.31 0.27 0.23 0.27
4066 || orf19.6981 || || || Ortholog of S. cerevisiae : YKR051W, C. glabrata CBS138 : CAGL0K08228g, C. dubliniensis CD36 : Cd36_85420, C. parapsilosis CDC317 : CPAR2_405720 and Candida tenuis NRRL Y-1498 : CANTEDRAFT_124861 || 1 0.77 0.47 0.55 0.33 1.05 0.85 0.15 -0.04 -0.31 -0.15 1.19 0.36 0.73 0.19 1.25 0.28
4067 || orf19.2111 || || || Ortholog(s) have core RNA polymerase II binding transcription factor activity and role in transcription elongation from RNA polymerase II promoter, transcriptional start site selection at RNA polymerase II promoter || 1 0.65 0.59 0.16 0.11 1.18 0.32 0.27 0.27 -0.11 0.23 0.82 0.24 0.29 0.03 1.10 -0.15
4068 || orf19.6152 || || || Ortholog(s) have mitochondrion localization || 1 0.49 0.59 0.56 0.36 1.43 1.42 0.62 0.05 0.44 0.76 0.50 0.12 0.23 0.00 1.33 -0.17
4069 || orf19.2971 || || || Ortholog of C. dubliniensis CD36 : Cd36_02630, C. parapsilosis CDC317 : CPAR2_108390, Candida tenuis NRRL Y-1498 : CANTEDRAFT_115724 and Debaryomyces hansenii CBS767 : DEHA2D07986g || 1 0.98 0.70 -0.09 0.30 1.35 1.21 0.37 0.06 0.85 0.61 0.84 0.69 0.61 -0.14 1.64 0.38
4070 || orf19.2229 || || || Ortholog(s) have ubiquitin-protein ligase activity, role in protein ubiquitination, response to ethanol and cytoplasm, nucleus localization || 1 0.92 0.88 0.82 0.60 1.29 0.97 0.50 0.20 0.36 0.28 0.72 0.80 0.53 0.02 1.55 -0.04
4071 || orf19.4400 || || || Has domain(s) with predicted role in anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process, regulation of mitotic metaphase/anaphase transition and anaphase-promoting complex localization || 1 0.51 0.46 0.43 0.42 0.88 0.94 0.10 0.16 0.13 0.41 0.46 0.98 0.22 -0.08 1.39 0.38
4072 || orf19.2850 || || || Protein of unknown function; induced by nitric oxide independent of Yhb1p || 1 0.06 0.40 0.28 0.20 1.08 0.92 0.03 0.18 0.07 0.46 0.36 0.52 0.14 0.39 1.60 0.23
4073 || orf19.706 || NMD3 || || Putative nonsense-mediated mRNA decay protein; repressed in core stress response; repressed by prostaglandins || 1 0.35 0.39 0.14 0.25 0.59 1.08 0.15 0.31 -0.06 0.94 0.32 0.02 0.23 0.51 0.57 0.49
4074 || orf19.5912 || MAK21 || || Putative 66S pre-ribosomal particle subunit; mutation confers hypersensitivity to tubercidin (7-deazaadenosine) || 1 1.17 0.75 0.30 0.06 1.88 2.21 0.62 1.25 0.27 2.16 0.50 0.28 0.45 1.45 0.81 1.27
4075 || orf19.2256 || || || Ortholog(s) have cytosol, nucleus localization || 1 0.55 0.69 0.12 0.19 0.74 1.14 0.57 0.73 0.47 1.41 0.85 0.29 0.70 1.19 0.43 0.48
4076 || orf19.5049 || || || Putative U3-containing 90S preribosome processome complex subunit; Hap43-induced gene; rat catheter and Spider biofilm induced; F-12/CO2 early biofilm induced || 1 1.23 1.19 0.63 -0.58 1.38 1.79 1.36 0.19 -0.19 1.65 0.57 -0.48 1.24 1.18 0.43 -0.32
4077 || orf19.3170 || || || Ortholog(s) have role in RNA Polymerase I assembly, RNA Polymerase II core complex assembly, RNA Polymerase III assembly, formation of translation preinitiation complex and cytoplasm, cytosolic ribosome localization || 1 0.21 0.33 0.04 0.01 1.30 1.73 0.24 0.11 -0.16 1.01 0.38 0.01 0.29 0.24 0.69 -0.50
4078 || orf19.2362 || || || Putative 90S preribosome component; Hap43p-induced gene; possibly an essential gene, disruptants not obtained by UAU1 method || 1 0.76 0.76 0.23 0.24 1.00 2.10 0.04 -0.06 -0.62 0.77 0.05 0.12 0.48 0.04 0.45 -0.29
4079 || orf19.4133 || || || Protein wth a predicted role in transcription from RNA polymerase II promoters; Spider biofilm induced || 1 0.79 0.74 0.30 0.20 1.67 1.80 0.13 -0.30 -0.37 0.15 -0.09 0.21 0.37 0.45 0.95 -0.68
4080 || orf19.3624 || MSU1 || || Ortholog(s) have exoribonuclease II activity, role in mitochondrial RNA catabolic process and mitochondrial degradosome localization || 1 1.13 1.03 0.35 0.10 1.42 1.40 0.34 0.21 0.16 0.79 0.02 0.06 0.41 0.17 0.28 -0.78
4081 || orf19.3624 || MSU1 || || Ortholog(s) have exoribonuclease II activity, role in mitochondrial RNA catabolic process and mitochondrial degradosome localization || 1 0.91 1.07 0.17 -0.01 1.47 1.43 0.18 0.23 -0.14 0.83 -0.06 0.41 0.10 -0.11 0.12 -0.36
4082 || orf19.4578 || CYT2 || || Cytochrome c1 heme lyase; transcript regulated by Nrg1; induced in high iron || 1 0.92 0.69 0.91 0.26 1.28 1.46 0.23 0.71 0.35 0.56 0.18 0.15 -0.12 0.05 0.71 0.18
4083 || orf19.1735 || || || Ortholog(s) have U2-type spliceosomal complex localization || 1 1.35 0.51 0.52 0.53 1.20 1.92 0.93 1.02 -0.00 0.87 0.73 0.80 0.05 0.46 1.12 0.25
4084 || orf19.3585 || || || Putative tRNA methyltransferase complex subunit; regulated by Gcn4; repressed in response to amino acid starvation (3-aminotriazole treatment); Spider biofilm induced || 1 0.86 0.94 0.24 -0.06 1.63 1.72 0.80 0.86 -0.87 0.67 1.08 0.40 0.63 -0.07 0.25 0.41
4085 || orf19.7603 || || || Protein with a predicted role in cytochrome c oxidase assembly; rat catheter biofilm induced || 1 0.79 0.74 -0.40 -0.73 2.64 1.84 0.78 0.82 0.24 0.20 0.81 0.24 0.01 0.16 0.95 -0.10
4086 || orf19.7322 || || || Protein of unknown function; S. cerevisae ortholog Ypl225w interacts with ribosomes; rat catheter biofilm induced || 1 0.83 0.89 0.07 -0.25 2.14 1.75 0.47 0.66 -0.19 0.27 1.01 0.05 -0.08 -0.13 0.67 0.34
4087 || orf19.7603 || || || Protein with a predicted role in cytochrome c oxidase assembly; rat catheter biofilm induced || 1 0.55 0.59 0.49 0.05 1.75 1.51 0.54 0.66 0.41 0.22 0.45 0.09 0.21 0.04 0.71 0.12
4088 || orf19.7322 || || || Protein of unknown function; S. cerevisae ortholog Ypl225w interacts with ribosomes; rat catheter biofilm induced || 1 1.38 1.31 0.38 0.18 2.50 1.97 0.74 1.27 0.07 0.38 1.52 0.25 0.60 0.08 1.31 0.37
4089 || orf19.2471 || GIM5 || || Putative heterohexameric cochaperone prefoldin complex subunit; macrophage/pseudohyphal-repressed gene and macrophage-induced protein || 1 0.72 0.88 -0.07 0.08 1.35 0.90 0.55 0.94 0.00 0.74 0.71 0.32 0.44 0.13 0.78 0.13
4090 || orf19.7016 || PHM5 || || Ortholog(s) have endopolyphosphatase activity, exopolyphosphatase activity, role in polyphosphate catabolic process and fungal-type vacuole membrane, nucleus localization || 1 0.61 0.62 0.48 0.43 1.72 1.93 0.62 0.62 0.06 0.03 1.14 0.36 0.76 -0.23 0.97 0.02
4091 || orf19.874 || || || Predicted mitochondrial i-AAA protease supercomplex; degrades misfolded mitochondrial proteins; Hap43-repressed gene || 1 0.24 0.33 0.19 0.11 1.09 0.57 0.13 0.31 0.14 0.17 0.60 0.09 0.15 0.36 0.60 0.15
4092 || orf19.5627 || || || S. cerevisiae ortholog Hek2/Khd1 is a putative RNA binding protein involved in the asymmetric localization of ASH1 mRNA; Hap43-induced gene || 1 0.51 0.55 0.27 0.26 0.97 0.90 0.24 0.42 0.09 0.42 0.53 0.28 0.90 0.22 1.19 -0.15
4093 || orf19.4662 || RLM1 || || Putative transcription factor; required for wild-type resistance to cell wall perturbation, caspofungin treatment; regulates caspofungin induction of PGA13 || 1 0.95 1.00 0.74 0.58 1.41 1.24 0.17 0.05 -0.21 0.16 0.23 0.31 1.53 0.81 1.33 0.08
4094 || orf19.4563 || || || Protein of unknown function; repressed by prostaglandins; Hap43-induced, Spider biofilm induced || 1 0.38 0.50 0.38 0.44 0.49 0.48 0.28 0.11 -0.20 0.32 0.15 0.18 0.74 0.13 0.62 -0.20
4095 || orf19.6989 || || || Putative U2 snRNP-associated protein; Spider biofilm induced || 1 0.79 1.15 0.42 0.65 1.93 1.59 0.74 -0.02 -0.44 0.94 0.97 0.10 2.29 0.38 0.91 -0.13
4096 || orf19.4659 || || || Ortholog(s) have RNA binding activity, role in mRNA splicing, via spliceosome and U2 snRNP, U2-type prespliceosome localization || 1 0.99 1.15 0.19 -0.15 1.22 1.41 0.49 0.09 -0.18 0.38 0.22 0.26 0.77 0.68 0.31 0.68
4097 || orf19.4659 || || || Ortholog(s) have RNA binding activity, role in mRNA splicing, via spliceosome and U2 snRNP, U2-type prespliceosome localization || 1 0.52 0.54 0.34 0.21 0.96 0.93 0.27 -0.01 -0.35 0.34 0.26 0.37 0.36 0.34 0.28 0.65
4098 || orf19.2260 || || || Putative transcription factor with zinc finger DNA-binding motif || 1 0.37 0.38 0.31 0.14 0.90 1.07 0.07 -0.10 -0.23 0.35 0.29 0.11 0.56 0.14 0.31 0.36
4099 || orf19.3568 || RXT3 || || Putative transcriptional repressor || 1 0.65 0.84 0.06 -0.03 1.24 1.39 0.07 0.16 -0.01 0.16 0.46 0.53 1.16 0.17 0.87 0.36
4100 || orf19.952 || || || Has domain(s) with predicted DNA binding activity || 1 0.63 0.65 0.20 0.16 1.37 1.23 0.41 0.21 0.42 0.09 0.66 0.22 0.91 0.27 0.56 0.65
4101 || orf19.3007 || || || Ortholog(s) have role in endosome organization, regulation of protein localization and BLOC-1 complex localization || 1 1.25 1.53 0.54 0.41 1.90 1.69 0.92 0.09 0.01 0.08 0.95 0.13 1.33 -0.01 1.10 0.82
4102 || orf19.1567 || || || Ortholog(s) have Rab guanyl-nucleotide exchange factor activity, phosphatidylinositol binding activity || 1 0.34 0.98 0.42 0.15 0.64 0.79 0.24 0.36 0.02 -0.08 0.50 0.11 0.68 0.22 0.39 0.49
4103 || orf19.910 || PRP3 || || Predicted splicing factor, component of the U4/U6-U5 snRNP complex; Hap43-induced gene; rat catheter biofilm induced || 1 0.41 0.64 0.28 -0.05 1.12 1.43 0.12 0.29 0.29 0.54 0.44 0.34 0.44 0.63 0.05 0.46
4104 || orf19.6625 || || || Ortholog(s) have acetyltransferase activator activity, histone binding activity and role in double-strand break repair via nonhomologous end joining, nucleosome assembly, positive regulation of histone acetylation || 1 0.67 0.46 0.14 0.38 1.00 1.40 0.11 0.38 0.51 0.85 0.94 0.42 0.40 0.76 0.26 0.32
4105 || orf19.4983 || || || Ortholog of C. dubliniensis CD36 : Cd36_12520, C. parapsilosis CDC317 : CPAR2_201720, Candida tenuis NRRL Y-1498 : CANTEDRAFT_108003 and Debaryomyces hansenii CBS767 : DEHA2D05214g || 1 0.49 0.57 0.34 0.16 1.21 1.06 0.61 0.27 0.60 0.57 0.61 0.14 0.23 0.19 0.40 0.28
4106 || orf19.6685 || ISY1 || || Putative pre-mRNA-splicing factor; mutation confers resistance to 5-fluorocytosine (5-FC); rat catheter biofilm induced || 1 0.95 1.27 1.27 0.98 1.92 2.29 1.13 0.43 1.33 1.30 1.14 0.21 1.03 1.01 0.59 0.35
4107 || orf19.2893 || || || Protein of unknown function; regulation correlates with clinical development of fluconazole resistance; transcript is upregulated in an RHE model of oral candidiasis || 1 0.60 0.68 0.39 0.20 0.90 1.08 0.03 -0.08 0.39 0.29 0.35 0.55 0.48 0.60 0.56 0.11
4108 || orf19.2893 || || || Protein of unknown function; regulation correlates with clinical development of fluconazole resistance; transcript is upregulated in an RHE model of oral candidiasis || 1 1.01 0.70 0.67 0.68 1.24 1.70 0.13 -0.20 0.63 0.62 0.50 0.44 0.31 0.80 0.50
4109 || orf19.3724 || || || Ortholog(s) have role in endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA and LSU-rRNA), more || 1 1.23 1.07 1.33 1.05 1.97 2.70 0.20 0.26 0.40 1.16 0.84 0.44 0.64 0.88 0.67 0.07
4110 || orf19.1753 || PUS7 || || Pseudouridine synthase; catalyzes pseudouridylation in U2 snRNA, 5S rRNA, cytoplasmic tRNAs and in pre-tRNA(Tyr); F-12/CO2 early biofilm induced || 1 0.49 0.71 0.89 0.52 1.35 1.69 0.08 0.08 0.14 0.83 0.16 0.26 0.54 -0.02 0.70 0.17
4111 || orf19.6316.4 || || || Protein of unknown function; Hap43-induced; rat catheter and Spider biofilm induced || 1 1.05 1.17 1.03 1.13 1.35 2.66 0.51 0.43 0.90 1.25 0.53 0.47 1.61 0.77 0.11 -0.29
4112 || orf19.154 || || || Putative ortholog of S. cerevisiae Utp30; a U3-containing 90S preribosome complex protein; Hap43-induced; Spider biofilm induced || 1 0.79 1.06 0.45 0.50 1.15 1.81 0.90 -0.00 0.09 0.61 0.55 0.22 0.83 0.08 0.01
4113 || orf19.2717 || SAS10 || || Putative U3-containing small subunit processome complex subunit; Hap43p-induced gene; mutation confers resistance to 5-fluorocytosine (5-FC); repressed upon high-level peroxide stress || 1 0.86 1.16 0.77 0.50 1.14 2.37 0.95 0.12 0.04 2.04 1.20 -0.20 1.39 1.28 0.94 -0.03
4114 || orf19.2386 || || || Ortholog(s) have role in endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA and LSU-rRNA), more || 1 0.71 1.32 1.16 0.55 1.56 2.51 0.63 0.34 0.25 1.41 0.64 -0.05 1.20 1.01 0.98 -0.65
4115 || orf19.5299 || ECM1 || || Putative pre-ribosomal factor; decreased mRNA abundance observed in cyr1 homozygous mutant hyphae; induced by heavy metal (cadmium) stress; Hog1p regulated || 1 0.87 1.25 0.98 0.68 1.33 2.52 0.33 0.85 0.23 1.96 0.65 -0.06 0.92 1.09 0.28 -0.40
4116 || orf19.6014 || RRS1 || || Putative ribosome biogenesis and nuclear export protein; Hap43p-induced gene; mutation confers hypersensitivity to 5-fluorocytosine (5-FC), 5-fluorouracil (5-FU), and tubercidin (7-deazaadenosine) || 1 1.15 1.15 0.66 0.67 1.32 1.64 0.74 0.84 0.02 1.67 0.86 -0.19 0.77 1.00 0.70 -0.45
4117 || orf19.2717 || SAS10 || || Putative U3-containing small subunit processome complex subunit; Hap43p-induced gene; mutation confers resistance to 5-fluorocytosine (5-FC); repressed upon high-level peroxide stress || 1 1.30 1.25 0.57 0.12 1.79 2.30 0.80 0.49 -0.18 2.11 0.51 -0.40 1.00 1.23 0.77 -0.36
4118 || orf19.3978 || || || Protein required for maturation of 18S rRNA; rat catheter biofilm repressed || 1 1.40 1.19 0.33 0.21 1.52 2.00 1.12 1.05 0.02 2.23 0.28 -0.68 0.87 1.28 0.74 -1.02
4119 || orf19.1609 || || || Ortholog(s) have role in endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) and mitotic spindle pole body, nucleolus localization || 1 0.47 0.61 0.57 0.38 0.59 1.40 0.45 0.29 -0.03 1.36 0.22 -0.48 0.51 0.50 0.03 -0.25
4120 || orf19.7650 || LTV1 || || Putative GSE complex component; repressed by prostaglandins || 1 0.49 0.64 0.58 0.71 1.07 1.42 0.10 0.37 -0.27 1.27 0.30 -0.23 0.19 0.38 0.45 -0.44
4121 || orf19.809 || || || Ortholog(s) have role in maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) and nucleolus, preribosome localization || 1 0.75 0.76 0.78 0.87 0.84 1.67 0.21 0.51 -0.32 0.95 0.29 -0.39 0.45 0.45 0.27 -0.14
4122 || orf19.5991 || || || Ortholog(s) have role in maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA), maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) || 1 0.94 0.64 0.74 0.40 1.39 1.84 0.24 0.65 -0.20 1.34 0.10 -0.19 0.47 0.26 0.45 0.07
4123 || orf19.6236 || NOP6 || || Putative ortholog of S. cerevisiae Nop6; role in ribosomal small subunit biogenesis; Spider biofilm induced || 1 2.12 2.33 1.12 0.80 2.31 2.49 0.96 1.05 -0.06 1.11 0.60 -0.18 0.79 0.34 0.61 -0.55
4124 || orf19.7160 || || || Ortholog(s) have unfolded protein binding activity || 1 1.04 1.25 0.73 0.52 1.06 1.37 0.57 0.85 0.19 1.01 0.67 -0.58 0.09 0.38 0.08 -0.29
4125 || orf19.7160 || || || Ortholog(s) have unfolded protein binding activity || 1 0.92 1.32 0.64 0.11 1.22 1.39 0.69 0.76 -0.14 1.09 0.60 -0.15 0.27 0.67 0.20 0.09
4126 || orf19.1045 || || || Putative U2 snRNP protein; Hap43p-induced gene; mutation confers hypersensitivity to 5-fluorocytosine (5-FC), 5-fluorouracil (5-FU), and tubercidin (7-deazaadenosine) || 1 1.14 1.18 0.31 0.31 1.65 2.20 0.82 1.22 0.65 1.20 1.27 0.76 0.62 0.60 0.74 0.56
4127 || orf19.6316.4 || || || Protein of unknown function; Hap43-induced; rat catheter and Spider biofilm induced || 1 1.77 1.25 0.56 0.24 2.49 2.89 1.13 1.92 0.63 1.78 1.00 0.46 1.72 1.17 1.36 0.26
4128 || orf19.5198 || NOP4 || || Putative nucleolar protein; Hap43-induced; mutation confers hypersensitivity to 5-fluorocytosine (5-FC), 5-fluorouracil (5-FU), and tubercidin (7-deazaadenosine); represses in core stress response || 1 1.88 1.22 0.78 0.65 1.94 2.67 1.06 0.74 0.03 1.54 0.63 -0.18 0.82 1.00 0.75 0.41
4129 || orf19.5198 || NOP4 || || Putative nucleolar protein; Hap43-induced; mutation confers hypersensitivity to 5-fluorocytosine (5-FC), 5-fluorouracil (5-FU), and tubercidin (7-deazaadenosine); represses in core stress response || 1 1.37 1.88 1.22 1.08 2.01 3.16 1.02 1.08 -0.05 1.98 1.12 -0.01 0.91 1.02 0.95 1.04
4130 || orf19.2237.1 || || || Ortholog of Slx9 required for pre-rRNA processing; associated with 90S pre-ribosome and 43S small ribosomal subunit precursor, interacts with U3 snoRNA in S. cerevisiae; gene has intron; Spider biofilm induced || 1 0.63 0.94 0.50 0.26 1.00 1.56 0.81 0.68 0.30 1.18 0.73 -0.08 0.46 0.44 0.70 -0.03
4131 || orf19.2831 || RPC31 || || Putative RNA polymerase III subunit C31; repressed by nitric oxide; induced during infection of murine kidney, compared to growth in vitro; has murine homolog || 1 1.35 1.19 0.87 0.70 1.56 1.61 0.40 0.81 0.51 0.99 0.86 0.01 1.02 0.58 0.68 0.36
4132 || orf19.7664 || || || Ortholog(s) have nucleolus localization || 1 1.58 1.73 0.69 0.85 1.60 1.99 0.98 1.67 0.12 1.28 1.19 -0.05 1.13 0.56 0.69 0.64
4133 || orf19.962 || || || Protein with a fungal RNA polymerase I subunit RPA14 domain; proposed to play a role in the recruitment of pol I to the promoter; Hap43-induced gene || 1 2.13 2.29 1.04 0.89 1.83 2.05 1.30 1.70 0.07 1.66 1.23 0.22 1.69 0.63 1.26 -0.31
4134 || orf19.962 || || || Protein with a fungal RNA polymerase I subunit RPA14 domain; proposed to play a role in the recruitment of pol I to the promoter; Hap43-induced gene || 1 2.16 2.55 1.09 0.95 2.40 2.18 1.46 1.36 0.16 1.97 1.46 -0.36 1.82 0.51 0.68 -0.19
4135 || orf19.3990 || || || Ortholog(s) have DNA-directed RNA polymerase activity, RNA polymerase III activity and role in tRNA transcription from RNA polymerase III promoter, transcription initiation from RNA polymerase III promoter || 1 2.00 1.94 0.64 0.25 1.95 2.08 1.71 1.25 0.10 1.63 1.87 0.40 1.62 0.75 1.65 -0.15
4136 || orf19.3990 || || || Ortholog(s) have DNA-directed RNA polymerase activity, RNA polymerase III activity and role in tRNA transcription from RNA polymerase III promoter, transcription initiation from RNA polymerase III promoter || 1 1.32 1.34 0.64 0.30 1.68 2.02 0.80 0.71 0.13 1.17 1.15 0.30 1.18 1.27 0.85 -0.05
4137 || orf19.5067 || || || Predicted nuclear exosome-associated nucleic acid binding protein; rat catheter and Spider biofilm induced || 1 1.84 1.33 0.86 0.83 2.30 2.73 1.00 0.75 -0.26 1.43 1.13 0.24 1.38 0.81 1.41 -0.28
4138 || orf19.5067 || || || Predicted nuclear exosome-associated nucleic acid binding protein; rat catheter and Spider biofilm induced || 1 1.54 1.31 0.50 0.39 2.05 2.05 1.55 0.60 -0.33 1.15 0.93 0.15 1.39 0.56 0.92 -0.39
4139 || orf19.5067 || || || Predicted nuclear exosome-associated nucleic acid binding protein; rat catheter and Spider biofilm induced || 1 1.48 1.37 0.88 0.46 2.14 2.44 1.59 0.74 0.00 1.47 1.36 -0.23 1.36 0.76 0.60 -0.22
4140 || orf19.7624 || || || Ortholog(s) have role in rRNA processing and 90S preribosome, nucleolus localization || 1 0.97 1.49 0.58 0.48 2.09 2.52 1.24 0.46 0.19 1.01 1.04 0.17 1.29 0.31 1.02 -0.36
4141 || orf19.1642 || || || Ortholog of S. cerevisiae Loc1, a nuclear protein involved in asymmetric localization of ASH1 mRNA in S. cerevisiae; Hap43-induced gene; Spider biofilm induced || 1 1.35 1.58 1.28 0.93 1.70 2.26 1.35 0.74 0.23 0.82 0.89 -0.06 1.34 0.38 0.94 -0.42
4142 || orf19.5067 || || || Predicted nuclear exosome-associated nucleic acid binding protein; rat catheter and Spider biofilm induced || 1 1.50 1.70 0.51 0.34 2.26 2.30 1.42 0.23 0.02 1.38 1.25 1.38 0.49 1.87 -0.66
4143 || orf19.6463 || || || Putative ortholog of S. cerevisiae Npa3p; possibly essential for growth (however, depletion mutant is viable) || 1 0.94 1.04 0.12 0.15 1.68 1.52 0.70 0.24 -0.32 1.12 0.82 0.28 0.67 0.13 1.22 -0.11
4144 || orf19.1642 || || || Ortholog of S. cerevisiae Loc1, a nuclear protein involved in asymmetric localization of ASH1 mRNA in S. cerevisiae; Hap43-induced gene; Spider biofilm induced || 1 0.64 1.16 0.20 0.24 1.15 2.04 0.59 0.60 -0.34 0.97 0.40 0.16 0.90 0.28 0.45 -0.22
4145 || orf19.2386 || || || Ortholog(s) have role in endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA and LSU-rRNA), more || 1 2.49 1.35 0.93 0.48 2.27 2.63 1.28 0.97 -0.58 1.30 0.80 -0.63 1.59 0.90 1.82 -0.79
4146 || orf19.3978 || || || Protein required for maturation of 18S rRNA; rat catheter biofilm repressed || 1 0.99 1.14 0.15 0.09 1.37 2.26 0.96 0.16 -0.39 0.89 1.05 -0.14 0.97 0.61 0.74 -0.86
4147 || orf19.5067 || || || Predicted nuclear exosome-associated nucleic acid binding protein; rat catheter and Spider biofilm induced || 1 1.49 1.61 0.74 0.20 2.16 2.60 2.06 1.14 -0.61 1.78 1.28 0.21 1.79 0.95 0.86 -1.87
4148 || orf19.7624 || || || Ortholog(s) have role in rRNA processing and 90S preribosome, nucleolus localization || 1 0.89 0.93 0.40 -0.14 2.04 1.85 1.07 0.31 -0.12 1.51 0.60 0.03 1.12 0.37 0.78 -0.85
4149 || orf19.2237.1 || || || Ortholog of Slx9 required for pre-rRNA processing; associated with 90S pre-ribosome and 43S small ribosomal subunit precursor, interacts with U3 snoRNA in S. cerevisiae; gene has intron; Spider biofilm induced || 1 1.47 1.57 0.28 0.04 2.27 2.06 1.90 1.07 0.30 1.86 1.02 -0.98 1.38 0.60 1.08 -0.43
4150 || orf19.1388 || || || Putative 66S pre-ribosomal particle component; Hap43-induced; F-12/CO2 early biofilm induced || 1 1.62 1.56 0.14 -0.07 1.70 1.69 1.74 1.54 -0.48 1.57 1.05 -0.48 1.26 0.33 0.80 -0.82
4151 || orf19.5991 || || || Ortholog(s) have role in maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA), maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) || 1 1.27 1.26 0.29 0.17 2.00 1.71 0.86 0.51 -0.48 1.28 0.63 -0.43 0.43 0.09 0.61 0.09
4152 || orf19.6463 || || || Putative ortholog of S. cerevisiae Npa3p; possibly essential for growth (however, depletion mutant is viable) || 1 1.00 1.04 0.36 0.16 1.67 1.66 0.32 0.18 -0.26 0.95 0.46 0.09 0.70 0.15 0.93 0.43
4153 || orf19.1772 || || || Ortholog(s) have mitochondrion localization || 1 1.31 1.38 -0.06 -0.12 2.09 2.35 0.58 0.02 -0.27 1.29 0.28 -0.27 0.94 0.19 1.11 -0.15
4154 || orf19.81 || || || Ortholog(s) have role in exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA and LSU-rRNA), more || 1 0.85 1.02 0.49 -0.29 1.55 1.41 0.52 0.02 -0.54 0.87 0.71 0.23 1.09 0.25 0.70 0.07
4155 || orf19.4492 || || || Ortholog(s) have role in nuclear division, rRNA processing and mitotic spindle pole body, nuclear periphery, nucleolus, preribosome, large subunit precursor localization || 1 0.72 0.85 0.33 -0.05 1.67 1.76 1.02 0.99 -0.19 1.92 1.37 -0.02 1.03 0.50 0.40 0.27
4156 || orf19.1753 || PUS7 || || Pseudouridine synthase; catalyzes pseudouridylation in U2 snRNA, 5S rRNA, cytoplasmic tRNAs and in pre-tRNA(Tyr); F-12/CO2 early biofilm induced || 1 0.32 0.59 -0.18 -0.31 1.89 2.19 0.54 0.51 -0.18 1.24 1.07 0.56 0.46 0.34 1.10 0.21
4157 || orf19.3170 || || || Ortholog(s) have role in RNA Polymerase I assembly, RNA Polymerase II core complex assembly, RNA Polymerase III assembly, formation of translation preinitiation complex and cytoplasm, cytosolic ribosome localization || 1 0.25 0.82 0.12 -0.35 1.51 1.95 0.31 0.14 0.34 0.92 0.51 0.41 0.62 0.29 0.63 0.22
4158 || orf19.2402 || SSU72 || || Ortholog(s) have CTD phosphatase activity, protein tyrosine phosphatase activity || 1 0.43 0.59 0.40 -0.29 1.35 1.30 0.11 0.11 0.07 0.43 0.53 0.27 0.31 0.21 0.70 0.44
4159 || orf19.2402 || SSU72 || || Ortholog(s) have CTD phosphatase activity, protein tyrosine phosphatase activity || 1 0.49 0.73 0.25 0.05 1.41 1.30 0.02 0.22 0.12 0.39 0.46 0.47 0.23 0.46 0.88 0.30
4160 || orf19.4033 || PRP22 || || Putative RNA-dependent ATPase; induced upon adherence to polystyrene; induced by Mnl1p under weak acid stress || 1 0.42 0.56 0.07 0.04 1.07 0.94 0.28 0.24 0.23 0.32 0.36 0.25 0.16 0.04 0.64 0.46
4161 || orf19.6476 || || || Putative protein with a predicted role in exocytic transport from the Golgi; filament induced || 1 0.34 1.02 0.28 0.18 1.08 1.41 0.24 0.06 0.44 0.75 0.54 0.34 0.63 0.50 0.91 0.28
4162 || orf19.2167 || || || Ortholog(s) have role in ribosomal large subunit biogenesis, ribosomal small subunit biogenesis and cytosolic large ribosomal subunit, nucleolus localization || 1 1.20 1.30 -0.35 0.41 2.34 2.70 1.03 0.64 0.21 2.43 1.18 0.54 1.43 1.16 1.94 -0.03
4163 || orf19.5066 || || || Putative pre-60S pre-ribosomal particle subunit; essential gene; S. cerevisiae ortholog RRP17 is essential; Hap43p-induced; rat catheter biofilm induced || 1 0.98 0.91 0.37 0.38 1.64 1.96 0.97 0.61 0.23 2.08 1.23 0.98 1.31 1.06 1.67 -0.33
4164 || orf19.2471 || GIM5 || || Putative heterohexameric cochaperone prefoldin complex subunit; macrophage/pseudohyphal-repressed gene and macrophage-induced protein || 1 0.36 0.65 0.24 -0.01 1.02 0.94 0.44 0.68 0.31 1.12 0.41 0.36 0.54 0.77 0.72 0.17
4165 || orf19.5430 || BUD21 || || Small-subunit processome component; repressed by prostaglandins || 1 0.55 0.87 0.51 0.01 0.96 1.96 0.79 0.91 0.03 1.41 1.08 0.81 0.48 0.58 1.41 0.01
4166 || orf19.4092 || || || Trimeric GatFAB AmidoTransferase(AdT) complex subunit; involved in the formation of Q-tRNAQ; repressed by fluphenazine treatment or in an azole-resistant strain that overexpresses CDR1; Spider biofilm induced || 1 0.59 0.62 0.01 0.20 1.09 1.08 0.28 0.49 0.12 0.66 0.63 0.73 0.18 0.44 0.58 0.05
4167 || orf19.5609 || || || Ortholog of C. dubliniensis CD36 : Cd36_63840, C. parapsilosis CDC317 : CPAR2_601510, Debaryomyces hansenii CBS767 : DEHA2A06270g and Pichia stipitis Pignal : PICST_31363 || 1 1.15 1.30 0.22 -0.19 1.46 1.84 0.13 1.14 -0.38 1.63 0.75 1.07 1.11 0.33 1.28 0.54
4168 || orf19.1296 || || || Ortholog(s) have role in spliceosomal snRNP assembly and U4/U6 x U5 tri-snRNP complex, mitochondrion localization || 1 0.55 0.63 0.30 -0.15 0.89 0.97 0.29 0.34 -0.40 0.51 0.25 0.51 0.49 0.50 0.63 -0.00
4169 || orf19.1091 || NOP8 || || Ortholog of S. cereviiae Nop8; has a role in ribosomal large subunit biogenesis; rat catheter and Spider biofilm induced || 1 1.39 0.93 0.25 0.08 2.21 2.30 1.57 0.72 -0.21 2.23 0.24 -0.52 0.79 0.49 1.77 -0.24
4170 || orf19.2723 || HIT1 || || Ortholog of S. cerevisiae Hit1; protein of unknown function required for high temperature growth; flow model biofilm induced; Spider biofilm induced || 1 1.23 1.17 0.64 -0.13 1.88 2.47 0.67 0.23 0.43 0.46 -0.01 -0.90 0.65 -0.30 0.50 -0.54
4171 || orf19.494 || || || Putative RNA-binding protein; role in assembly of box H/ACA snoRNPs and thus pre-rRNA processing; Spider biofilm induced || 1 1.03 1.27 0.71 0.44 1.87 2.31 0.62 0.07 0.05 1.12 -0.30 -0.99 1.15 0.35 0.75 -0.35
4172 || orf19.2712 || HCA4 || || Putative role in regulation of cell wall biogenesis; Hap43p-induced gene; possibly an essential gene, disruptants not obtained by UAU1 method; flow model and rat catheter biofilm induced || 1 0.78 0.99 0.91 0.51 1.71 2.46 0.45 0.49 -0.17 0.67 0.36 -0.57 0.76 0.35 0.37 -0.47
4173 || orf19.6298 || SPB4 || || Putative ATP-dependent RNA helicase; flucytosine repressed; Spider biofilm induced || 1 0.69 0.74 1.08 0.85 1.35 1.93 0.34 0.15 -0.01 0.52 0.17 -0.23 0.53 -0.05 0.64 -0.53
4174 || orf19.6298 || SPB4 || || Putative ATP-dependent RNA helicase; flucytosine repressed; Spider biofilm induced || 1 0.83 1.28 0.82 0.76 1.50 2.18 0.22 0.17 0.39 0.43 0.05 -0.54 1.00 -0.46 0.64 -0.83
4175 || orf19.59 || REI1 || || Putative cytoplasmic pre-60S factor; Hap43-induced; repressed by prostaglandins || 1 1.14 0.97 0.82 1.00 1.47 2.33 0.98 0.69 0.80 1.15 0.31 -0.22 0.77 0.33 0.46 -0.75
4176 || orf19.2564 || || || Putative nucleolar protein; implicated in ribosome biogenesis; rat catheter biofilm repressed || 1 1.18 1.19 1.14 0.74 1.69 2.68 1.09 0.62 0.93 0.69 0.55 0.11 1.61 0.52 0.88 -1.87
4177 || orf19.3161 || || || Ortholog(s) have ATPase activator activity, RNA binding activity || 1 0.74 1.01 1.12 0.57 1.22 1.50 0.41 -0.10 0.58 0.47 0.26 -0.27 0.56 0.51 0.17 -0.38
4178 || orf19.792 || || || Ortholog(s) have protein serine/threonine kinase activity, role in activation of bipolar cell growth, protein phosphorylation, regulation of cytokinesis, regulation of mitotic sister chromatid segregation and cytosol, nucleus localization || 1 0.67 0.79 0.51 0.63 0.85 1.51 0.04 -0.03 0.64 0.67 -0.25 -0.30 1.17 0.89 0.09 0.04
4179 || orf19.7107 || || || Ortholog(s) have role in ribosomal large subunit biogenesis and cytoplasm, nucleus, ribosome localization || 1 1.32 1.58 1.43 1.13 1.83 2.01 0.32 0.65 0.69 1.67 0.13 -0.64 1.05 0.73 0.44 0.49
4180 || orf19.3431 || || || Ortholog(s) have 3'-5' exonuclease activity, DNA-directed DNA polymerase activity, role in mitochondrial DNA replication and mitochondrion localization || 1 0.71 0.72 0.69 0.40 0.61 0.58 0.57 0.17 0.25 0.58 0.08 -0.03 0.68 0.29 -0.19 0.13
4181 || orf19.5841 || || || Ortholog of C. dubliniensis CD36 : Cd36_17700, C. parapsilosis CDC317 : CPAR2_212340, Candida tenuis NRRL Y-1498 : CANTEDRAFT_101113 and Debaryomyces hansenii CBS767 : DEHA2G03784g || 1 0.72 0.78 0.20 0.18 0.60 0.35 0.63 0.82 0.56 0.48 0.38 0.22 0.24 0.16 -0.00 0.09
4182 || orf19.1291 || ABZ1 || || Ortholog(s) have 4-amino-4-deoxychorismate synthase activity, role in para-aminobenzoic acid biosynthetic process and cytosol, nucleus localization || 1 0.64 0.90 0.46 0.30 0.49 0.77 0.78 0.68 1.18 0.64 0.48 -0.02 0.43 -0.14 0.46 -0.07
4183 || orf19.5296 || || || Ortholog(s) have role in mitochondrial respiratory chain complex IV assembly and integral to mitochondrial inner membrane localization || 1 0.44 0.62 0.34 -0.13 0.69 0.41 0.88 0.84 1.06 0.70 0.10 0.24 0.92 0.15 0.44 -0.09
4184 || orf19.6225.1 || || || Ortholog(s) have role in mitochondrial respiratory chain complex IV assembly and mitochondrion localization || 1 0.83 0.99 0.39 -0.38 2.16 1.70 1.37 1.18 1.29 -0.00 0.43 -0.11 0.89 0.73 0.37 0.65
4185 || orf19.6225.1 || || || Ortholog(s) have role in mitochondrial respiratory chain complex IV assembly and mitochondrion localization || 1 0.75 0.74 0.00 0.20 2.07 1.52 1.39 0.80 0.66 -0.54 0.14 -0.27 0.74 0.28 0.06 0.31
4186 || orf19.494 || || || Putative RNA-binding protein; role in assembly of box H/ACA snoRNPs and thus pre-rRNA processing; Spider biofilm induced || 1 1.96 0.94 1.10 0.65 1.33 2.05 1.15 0.90 0.32 0.03 0.14 -0.19 1.00 0.30 0.97 -0.20
4187 || orf19.7272 || || || Protein of unknown function; transcript detected on high-resolution tiling arrays || 1 1.41 1.26 0.98 0.88 1.69 1.49 0.88 0.95 0.94 0.59 0.46 -0.39 1.16 0.75 0.69 0.40
4188 || orf19.1417 || || || Ortholog of C. dubliniensis CD36 : Cd36_43970, C. parapsilosis CDC317 : CPAR2_401720, Candida tenuis NRRL Y-1498 : CANTEDRAFT_102588 and Debaryomyces hansenii CBS767 : DEHA2G16698g || 1 1.99 1.97 1.11 0.58 1.91 1.72 1.47 1.40 1.34 0.17 0.88 -0.04 1.50 0.47 1.05 -0.20
4189 || orf19.1417 || || || Ortholog of C. dubliniensis CD36 : Cd36_43970, C. parapsilosis CDC317 : CPAR2_401720, Candida tenuis NRRL Y-1498 : CANTEDRAFT_102588 and Debaryomyces hansenii CBS767 : DEHA2G16698g || 1 1.90 2.25 0.78 0.89 1.71 1.50 1.36 1.59 0.97 0.12 0.43 -0.20 1.21 0.59 1.30 -0.02
4190 || orf19.4842 || || || Protein of unknown function; Spider biofilm induced || 1 2.42 2.72 1.63 1.35 2.79 2.90 2.09 2.01 2.21 0.19 -0.46 -0.73 1.88 0.61 2.23 -0.60
4191 || orf19.4842 || || || Protein of unknown function; Spider biofilm induced || 1 1.60 1.97 1.69 1.00 2.36 3.07 1.57 1.53 2.28 0.16 -0.29 -0.34 1.35 0.56 1.68 -0.29
4192 || orf19.1336.2 || || || Ortholog(s) have role in mitochondrial respiratory chain complex assembly and mitochondrial intermembrane space, nucleus localization || 1 0.52 0.69 0.31 -0.07 0.90 0.94 0.69 1.01 1.18 0.28 0.12 0.25 0.34 0.11 0.53 -0.25
4193 || orf19.1336.2 || || || Ortholog(s) have role in mitochondrial respiratory chain complex assembly and mitochondrial intermembrane space, nucleus localization || 1 0.75 0.62 0.40 -0.06 1.06 1.16 0.99 0.85 1.06 0.26 0.19 0.19 0.52 0.04 0.54 0.18
4194 || orf19.4967 || COX19 || || Putative cytochrome c oxidase assembly protein; Plc1-regulated; rat catheter biofilm induced || 1 1.23 1.45 0.08 -0.34 1.42 1.36 1.15 1.14 1.26 0.11 0.10 0.57 0.69 0.34 1.28 0.31
4195 || orf19.1667.1 || || || Ortholog(s) have role in mitochondrial respiratory chain complex IV assembly and mitochondrial intermembrane space, nucleus localization || 1 1.33 1.48 0.66 -0.19 2.24 2.55 1.51 1.54 1.24 -0.26 0.79 0.09 0.85 -0.07 1.33 0.38
4196 || orf19.1114 || || || Cytochrome c oxidase subunit; membrane-localized protein; rat catheter biofilm induced || 1 1.83 1.59 0.57 -0.08 2.54 2.41 1.73 1.45 1.24 0.42 -0.34 -0.59 1.25 0.34 1.42 -0.29
4197 || orf19.4967 || COX19 || || Putative cytochrome c oxidase assembly protein; Plc1-regulated; rat catheter biofilm induced || 1 1.00 1.10 -0.18 -0.37 1.25 1.12 1.07 0.71 0.86 0.08 -0.23 -0.22 0.51 0.15 1.07 -0.12
4198 || orf19.5920 || || || Ortholog of C. dubliniensis CD36 : Cd36_84570, C. parapsilosis CDC317 : CPAR2_404420, Candida tenuis NRRL Y-1498 : CANTEDRAFT_115339 and Debaryomyces hansenii CBS767 : DEHA2G13618g || 1 1.28 1.31 0.67 0.26 1.53 0.92 0.88 1.24 1.34 0.62 0.18 0.08 0.18 -0.18 0.94 -0.75
4199 || orf19.5029 || MODF || || Ortholog(s) have mitochondrion localization || 1 0.65 0.87 0.59 0.58 0.91 0.28 0.73 0.60 0.64 0.28 -0.29 0.04 0.31 0.67 0.76 -0.32
4200 || orf19.792 || || || Ortholog(s) have protein serine/threonine kinase activity, role in activation of bipolar cell growth, protein phosphorylation, regulation of cytokinesis, regulation of mitotic sister chromatid segregation and cytosol, nucleus localization || 1 0.88 1.68 0.43 0.67 0.51 0.72 1.25 0.94 0.56 0.56 -0.56 -0.23 0.80 1.14 0.71 -0.40
4201 || orf19.3851 || || || Protein of unknown function; induced by alpha pheromone in SpiderM medium || 1 0.78 0.56 0.08 0.57 0.75 0.52 0.71 0.74 0.64 0.32 -0.16 -0.33 1.04 0.86 0.87 -0.22
4202 || orf19.3851 || || || Protein of unknown function; induced by alpha pheromone in SpiderM medium || 1 0.74 0.78 0.76 1.23 1.03 0.93 0.80 0.91 1.02 0.46 0.02 0.05 1.24 1.15 0.91 0.26
4203 || orf19.4858 || VPS41 || || Protein similar to S. cerevisiae Vps41p, which is involved in vacuole organization and biogenesis; transposon mutation affects filamentous growth; regulated by Gcn4p; induced in response to amino acid starvation (3-aminotriazole treatment) || 1 0.81 0.50 0.54 0.62 0.63 0.46 0.32 0.53 0.70 0.25 -0.23 -0.08 0.75 0.55 0.46 0.16
4204 || orf19.3851 || || || Protein of unknown function; induced by alpha pheromone in SpiderM medium || 1 0.59 0.64 0.29 0.41 0.75 0.25 0.58 0.64 0.14 -0.09 0.19 -0.28 0.79 0.62 0.69 0.17
4205 || orf19.2005 || REG1 || || Putative protein phosphatase regulatory subunit; Hap43-repressed gene; macrophage/pseudohyphal-induced; possibly regulated upon hyphal formation; flow model biofilm induced || 1 0.92 1.00 0.46 0.42 0.39 0.09 0.36 0.39 0.29 -0.10 0.27 -0.28 0.59 0.43 0.53 0.05
4206 || orf19.6031 || VPS27 || || Putative ESCRT-0 complex protein with a role in multivesicular body (MVB) trafficking || 1 0.74 0.72 0.30 0.19 0.47 0.21 0.33 0.28 0.21 -0.01 0.24 -0.02 0.65 0.27 0.67 0.27
4207 || orf19.2005 || REG1 || || Putative protein phosphatase regulatory subunit; Hap43-repressed gene; macrophage/pseudohyphal-induced; possibly regulated upon hyphal formation; flow model biofilm induced || 1 0.77 0.89 0.33 0.43 0.57 0.27 0.30 0.38 0.38 -0.01 0.49 0.23 0.67 0.74 0.88 0.09
4208 || orf19.6900 || || || Ortholog(s) have role in establishment or maintenance of cell polarity, mitochondrial genome maintenance, mitochondrion inheritance, phospholipid transport, protein import into mitochondrial outer membrane || 1 0.27 0.60 0.11 0.26 0.50 0.25 0.63 0.05 0.13 -0.00 0.30 0.06 0.47 0.43 0.52 0.18
4209 || orf19.4498 || || || Ortholog of C. dubliniensis CD36 : Cd36_19120, C. parapsilosis CDC317 : CPAR2_103880, Candida tenuis NRRL Y-1498 : CANTEDRAFT_115581 and Debaryomyces hansenii CBS767 : DEHA2F08426g || 1 0.95 0.90 0.56 0.50 0.88 1.13 0.81 0.88 0.21 0.50 0.38 0.12 0.76 1.53 0.59 0.28
4210 || orf19.7079 || || || Ortholog(s) have role in axial cellular bud site selection and cellular bud neck contractile ring localization || 1 0.52 0.53 0.75 0.38 0.59 0.87 0.68 0.88 0.40 0.03 0.34 -0.26 0.94 0.28 0.65 0.19
4211 || orf19.1029 || RPP1 || || Putative ortholog of S. cerevisiae Rpp1; subunit of both RNase MRP and nuclear RNase P; rat catheter and Spider biofilm induced || 1 0.90 0.73 1.09 0.82 0.75 1.61 0.60 1.59 0.41 0.42 0.22 -0.48 1.64 0.31 0.44 -0.64
4212 || orf19.2753 || ZCF15 || || Predicted Zn(II)2Cys6 transcription factor of unknown function; rat catheter biofilm induced || 1 1.11 1.17 0.00 0.32 1.49 0.94 0.69 0.51 0.03 0.13 -0.22 -0.40 0.75 0.11 0.93 -0.08
4213 || orf19.2753 || ZCF15 || || Predicted Zn(II)2Cys6 transcription factor of unknown function; rat catheter biofilm induced || 1 0.94 1.02 -0.08 0.25 1.27 0.71 0.71 0.35 0.02 0.07 -0.40 -0.25 0.95 0.19 0.87 -0.35
4214 || orf19.5573 || || || Protein of unknown function; expression downregulated in an ssr1 null mutant || 1 0.92 0.41 0.34 0.04 0.87 1.04 0.53 0.01 0.72 0.07 -0.29 -0.38 0.26 -0.07 0.46 -0.16
4215 || orf19.3310 || || || Protein of unknown function; Hap43-repressed; rat catheter and Spider biofilm induced || 1 0.57 0.71 0.82 0.82 1.28 1.68 0.10 0.12 0.59 -0.53 -0.46 -0.35 0.71 0.06 0.44 -0.29
4216 || orf19.1169 || || || Putative DnaJ-like molecular chaperone; Spider biofilm induced || 1 1.15 1.02 0.98 0.54 1.57 2.48 0.74 0.36 1.01 -0.76 -0.41 -0.67 0.68 -0.02 0.68 0.25
4217 || orf19.4315 || || || Ortholog(s) have Rab GTPase activator activity, role in vesicle-mediated transport and intracellular localization || 1 0.57 0.62 0.57 0.33 0.97 1.05 0.35 0.21 0.29 -0.21 -0.22 -0.34 0.46 0.52 0.04 0.06
4218 || orf19.692 || || || Protein of unknown function; Hap43-repressed gene; rat catheter and Spider biofilm induced || 1 0.47 0.74 0.38 0.19 1.04 1.10 -0.24 -0.33 0.23 0.02 0.25 -0.61 0.97 -0.03 0.09 -0.20
4219 || orf19.2667 || RPF1 || || Putative nucleolar protein with a predicted role in the assembly and export of the large ribosomal subunit; essential for growth; rat catheter and Spider biofilm induced || 1 0.73 0.92 1.16 0.57 1.01 1.16 0.15 -0.15 0.04 0.25 0.16 -0.67 0.95 -0.17 0.08 -0.55
4220 || orf19.7209 || || || Putative Rho GDP dissociation inhibitor; induced by nitric oxide independent of Yhb1p || 1 0.51 1.01 0.90 1.27 1.48 1.46 0.37 -0.15 -0.10 -0.08 0.08 -0.70 1.35 0.71 0.53 -0.65
4221 || orf19.2604 || || || S. pombe ortholog SPAC2C4.06c is a predicted tRNA (cytosine-5-)-methyltransferase; Spider biofilm induced || 1 0.92 0.60 0.89 1.20 1.10 1.62 0.47 0.06 -0.27 -0.08 -0.17 -0.87 0.64 -0.32 0.60 -0.14
4222 || orf19.4315 || || || Ortholog(s) have Rab GTPase activator activity, role in vesicle-mediated transport and intracellular localization || 1 0.61 0.50 0.36 0.38 0.93 0.53 0.23 0.22 0.09 -0.32 -0.21 -0.11 0.20 0.23 0.21 -0.21
4223 || CaalfMp12 || NAD4L || || Subunit 4L of NADH:ubiquinone oxidoreductase (NADH:ubiquinone dehydrogenase), a multisubunit enzyme complex (complex I) of the mitochondrial inner membrane that catalyzes the first step in mitochondrial respiration || 1 1.17 1.22 0.61 0.77 1.20 0.57 0.15 0.13 -0.13 -0.61 -0.08 -0.44 0.62 -0.12 0.57 -0.56
4224 || orf19.7365 || || || Ortholog(s) have ubiquitin-protein ligase activity and role in negative regulation of apoptotic process, negative regulation of gluconeogenesis, proteasome-mediated ubiquitin-dependent protein catabolic process || 1 0.71 0.83 0.15 0.62 0.98 0.44 0.03 0.14 -0.06 -0.55 0.47 -0.15 0.84 0.53 0.96 -0.26
4225 || CaalfMp07 || ATP8 || || Subunit 8 of the F0 sector of mitochondrial F1F0 ATP synthase, which is a large, evolutionarily conserved enzyme complex required for ATP synthesis || 1 1.35 1.33 0.28 0.72 1.42 1.05 0.61 0.16 -0.36 -0.77 0.70 0.18 1.03 -0.04 0.87 -0.33
4226 || orf19.871 || || || Ortholog(s) have protein transporter activity, role in Golgi to plasma membrane transport, intracellular protein transport and vesicle coat localization || 1 1.05 1.43 0.69 1.04 1.48 1.14 0.14 0.14 -0.80 -0.87 0.64 0.35 1.14 0.35 0.60 0.44
4227 || orf19.1975 || || || Ortholog(s) have role in mRNA splicing, via spliceosome, regulation of DNA methylation and U4/U6 x U5 tri-snRNP complex, U5 snRNP localization || 1 0.29 0.51 0.61 0.22 0.94 1.04 0.09 0.21 -0.08 -0.28 0.30 0.06 0.36 -0.11 0.54 -0.23
4228 || orf19.5059 || GCS1 || || Gamma-glutamylcysteine synthetase; glutathione synthesis, required for virulence;induced in low iron, H2O2, Cd, or presence of human neutrophils; possibly adherence-induced; Spider and F-12/CO2 biofilm induced || 1 0.48 0.36 0.69 0.39 0.80 0.69 0.07 0.13 0.61 -0.21 0.13 -0.04 0.60 0.02 0.38 -0.08
4229 || orf19.896 || CHK1 || || Histidine kinase; 2-component signaling, cell wall synthesis; hyphal growth defect; avirulent in mouse, not rat vaginal infection; phagocytosis rate increased; Spider biofilm induced; required for RPMI biofilm; Bcr1-induced in a/a biofilm || 1 0.53 0.84 1.27 1.05 1.46 1.82 -0.15 -0.14 0.14 -0.05 -0.10 -0.16 0.78 0.38 1.11 -0.34
4230 || orf19.5727 || || || Ortholog of C. dubliniensis CD36 : Cd36_64130, C. parapsilosis CDC317 : CPAR2_601230, Candida tenuis NRRL Y-1498 : CANTEDRAFT_115908 and Debaryomyces hansenii CBS767 : DEHA2E12540g || 1 0.34 0.69 0.87 0.51 1.28 1.08 -0.24 -0.00 0.23 -0.39 0.12 0.20 1.20 -0.08 0.75 -0.03
4231 || CaalfMp15 || COX3B || || Subunit III of cytochrome c oxidase, which is the terminal member of the mitochondrial inner membrane electron transport chain; identical to Cox3Ap; one of three mitochondrially-encoded subunits || 1 0.55 0.65 0.64 1.13 0.92 -0.09 0.05 -0.05 -0.55 -0.08 0.06 0.76 0.02 0.71 0.18
4232 || CaalfMp15 || COX3B || || Subunit III of cytochrome c oxidase, which is the terminal member of the mitochondrial inner membrane electron transport chain; identical to Cox3Ap; one of three mitochondrially-encoded subunits || 1 0.67 0.69 0.58 0.63 1.36 1.13 0.01 0.05 0.02 -0.39 -0.02 0.42 0.75 0.42 0.79 0.14
4233 || orf19.7337 || || || Protein with a nischarin related domain and leucine rich repeats; Spider biofilm induced || 1 1.43 1.27 0.54 0.54 1.80 1.51 0.09 -0.04 0.03 -0.29 0.54 0.44 1.13 0.38 0.77 0.45
4234 || orf19.871 || || || Ortholog(s) have protein transporter activity, role in Golgi to plasma membrane transport, intracellular protein transport and vesicle coat localization || 1 1.62 1.62 1.72 1.43 1.88 1.61 0.18 0.14 0.20 -0.56 0.86 0.55 1.67 0.66 1.27 0.38
4235 || CaalfMp12 || NAD4L || || Subunit 4L of NADH:ubiquinone oxidoreductase (NADH:ubiquinone dehydrogenase), a multisubunit enzyme complex (complex I) of the mitochondrial inner membrane that catalyzes the first step in mitochondrial respiration || 1 1.50 1.42 1.14 1.20 1.62 1.75 0.29 0.09 0.23 -0.31 0.16 0.13 1.08 -0.10 0.74 0.21
4236 || orf19.4593 || RGA2 || || Putative GTPase-activating protein (GAP) for Rho-type GTPase Cdc42; involved in cell signaling pathways controlling cell polarity; induced by low-level peroxide stress; flow model biofilm induced || 1 0.60 0.72 0.65 0.65 1.14 0.75 0.14 0.18 0.27 -0.03 -0.17 -0.14 0.57 0.19 0.61 -0.24
4237 || orf19.4593 || RGA2 || || Putative GTPase-activating protein (GAP) for Rho-type GTPase Cdc42; involved in cell signaling pathways controlling cell polarity; induced by low-level peroxide stress; flow model biofilm induced || 1 0.56 0.66 0.87 0.88 1.09 0.69 0.04 0.05 0.29 0.14 -0.18 0.13 0.50 0.24 0.53 -0.18
4238 || orf19.2565 || || || Predicted intermediate filament protein; required for nuclear and mitochondrial transmission to daughter buds in S. cerevisiae; Spider biofilm induced || 1 0.20 0.48 0.71 0.51 0.59 0.42 0.02 0.03 0.29 -0.09 -0.06 0.25 0.53 0.18 0.50 0.07
4239 || orf19.7033 || || || Putative dual specificity protein phosphatase, similar to S. cerevisiae Pps1p || 1 0.59 0.88 1.16 1.17 0.98 0.68 0.32 0.28 0.09 0.04 -0.14 0.27 0.86 0.24 0.51 0.23
4240 || orf19.4315 || || || Ortholog(s) have Rab GTPase activator activity, role in vesicle-mediated transport and intracellular localization || 1 0.60 0.84 0.98 0.78 0.91 0.72 0.26 0.54 0.57 -0.11 0.03 -0.10 0.81 0.28 0.52 0.07
4241 || orf19.1297 || || || Ortholog(s) have phosphatidylinositol-3-phosphate binding activity and role in CVT pathway, early endosome to Golgi transport, macroautophagy, mitochondrion degradation || 1 0.73 0.92 0.94 0.94 0.78 1.18 0.29 0.22 0.16 -0.13 -0.28 0.10 0.75 0.24 0.84 0.72
4242 || orf19.7365 || || || Ortholog(s) have ubiquitin-protein ligase activity and role in negative regulation of apoptotic process, negative regulation of gluconeogenesis, proteasome-mediated ubiquitin-dependent protein catabolic process || 1 1.13 1.15 0.70 0.74 1.02 0.52 0.14 0.28 0.13 -0.09 0.54 0.12 0.50 0.62 1.03 0.39
4243 || orf19.337 || VTI1 || || Ortholog(s) have SNAP receptor activity and role in Golgi to vacuole transport, intra-Golgi vesicle-mediated transport, vacuole fusion, non-autophagic, vesicle fusion || 1 0.87 0.90 0.72 0.45 0.75 0.63 0.14 0.40 0.01 0.19 0.30 0.27 0.20 0.30 0.84 0.22
4244 || orf19.337 || VTI1 || || Ortholog(s) have SNAP receptor activity and role in Golgi to vacuole transport, intra-Golgi vesicle-mediated transport, vacuole fusion, non-autophagic, vesicle fusion || 1 1.45 1.31 0.83 0.81 0.72 0.65 0.25 0.56 0.03 0.16 0.53 0.25 0.36 -0.12 0.82 0.17
4245 || orf19.2889 || || || Ortholog(s) have role in chromatin remodeling and Ino80 complex, cytoplasm localization || 1 1.95 2.87 1.25 1.24 1.49 1.54 0.58 0.83 -0.19 1.17 0.97 0.14 1.27 0.63 1.45 0.16
4246 || orf19.3201 || MTLA1 || || Homeodomain protein of the MTLa mating type locus; a1 and alpha2 together repress white-opaque switching and mating (an opaque-specific process); a/alpha mating type may increase virulence by competitive advantage; Spider biofilm induced || 1 1.08 1.13 0.70 0.66 1.09 0.79 0.48 0.36 0.33 0.38 0.28 0.50 0.63 0.51 0.90 -0.19
4247 || orf19.910 || PRP3 || || Predicted splicing factor, component of the U4/U6-U5 snRNP complex; Hap43-induced gene; rat catheter biofilm induced || 1 0.79 1.45 0.75 0.73 1.27 1.21 0.23 0.40 0.28 0.45 0.66 0.19 0.56 0.26 0.36 -0.06
4248 || orf19.1482 || HSK3 || || Subunit of the Dam1 (DASH) complex, which acts in chromosome segregation by coupling kinetochores to spindle microtubules; expression regulated during planktonic growth || 1 0.96 1.44 0.97 0.84 1.95 1.48 0.30 0.34 -0.09 0.33 0.92 0.07 0.84 0.54 1.15 0.16
4249 || orf19.367 || CNH1 || || Na+/H+ antiporter; required for wild-type growth, cell morphology, and virulence in a mouse model of systemic infection; not transcriptionally regulated by NaCl; fungal-specific (no human or murine homolog) || 1 0.81 0.82 0.54 0.46 1.22 1.39 0.47 0.45 0.09 0.39 0.45 -0.02 0.87 0.50 1.12 0.06
4250 || orf19.3201 || MTLA1 || || Homeodomain protein of the MTLa mating type locus; a1 and alpha2 together repress white-opaque switching and mating (an opaque-specific process); a/alpha mating type may increase virulence by competitive advantage; Spider biofilm induced || 1 1.20 0.83 0.61 0.47 0.86 0.99 0.46 0.04 0.14 0.19 0.39 0.38 0.21 0.13 0.58 0.02
4251 || orf19.1281 || || || Putative splicing factor required for the first step of pre-mRNA splicing; Spider biofilm induced || 1 1.13 1.02 0.76 0.42 1.31 1.32 0.23 0.22 -0.46 0.13 0.56 -0.47 0.60 0.25 0.60 0.16
4252 || orf19.1281 || || || Putative splicing factor required for the first step of pre-mRNA splicing; Spider biofilm induced || 1 1.02 1.08 0.62 0.73 1.07 1.25 0.55 0.49 -0.33 0.26 0.14 -0.21 0.40 0.79 0.44 0.18
4253 || orf19.340 || || || Ortholog(s) have role in protein targeting to membrane, protein targeting to vacuole and ESCRT I complex localization || 1 1.24 1.06 0.99 0.94 1.42 1.50 0.19 0.60 -0.00 -0.09 -0.19 -0.03 0.34 0.34 0.58 0.62
4254 || orf19.340 || || || Ortholog(s) have role in protein targeting to membrane, protein targeting to vacuole and ESCRT I complex localization || 1 0.80 0.82 0.55 0.44 1.05 1.30 0.07 0.15 -0.11 -0.41 -0.24 0.02 0.07 0.23 0.14 0.21
4255 || orf19.6168 || || || Ortholog of C. dubliniensis CD36 : Cd36_80830, Debaryomyces hansenii CBS767 : DEHA2F17930g, Candida tropicalis MYA-3404 : CTRG_04030 and Candida lusitaniae ATCC 42720 : CLUG_04224 || 1 1.36 1.16 0.98 0.99 1.08 0.76 0.56 0.28 0.05 -0.27 -0.27 -0.11 0.09 0.15 0.90 0.30
4256 || orf19.697 || || || Ortholog(s) have mitochondrial outer membrane localization || 1 0.92 0.68 0.51 0.70 0.85 0.47 0.26 0.45 0.41 -0.10 -0.06 -0.14 0.20 0.15 0.62 0.16
4257 || orf19.7006 || || || Ortholog(s) have role in reciprocal meiotic recombination || 1 1.12 1.17 1.00 0.87 1.44 1.41 -0.17 -0.71 0.27 0.10 -0.22 -0.32 0.17 -0.10 0.92 0.06
4258 || orf19.86 || || || Putative glutathione peroxidase; induced by peroxide, exposure to neutrophils and macrophage blood fractions; repressed during infection of macrophages; Spider biofilm induced; flow model biofilm repressed || 1 1.21 1.11 0.84 0.54 1.36 1.37 -0.01 0.02 -0.18 -0.40 -0.54 -0.30 -0.09 -0.59 0.88 -0.39
4259 || orf19.6453 || || || Ortholog of C. dubliniensis CD36 : Cd36_72300, C. parapsilosis CDC317 : CPAR2_703060, Candida tenuis NRRL Y-1498 : CANTEDRAFT_92002 and Debaryomyces hansenii CBS767 : DEHA2B06028g || 1 0.54 0.46 0.22 0.24 0.44 0.41 0.01 -0.01 -0.01 -0.06 -0.12 0.23 0.08 -0.10 0.35 -0.06
4260 || orf19.4110 || || || Ortholog of C. dubliniensis CD36 : Cd36_20490, C. parapsilosis CDC317 : CPAR2_104180, Candida tenuis NRRL Y-1498 : CANTEDRAFT_116074 and Debaryomyces hansenii CBS767 : DEHA2F05148g || 1 0.68 0.89 0.52 0.57 0.92 1.02 -0.09 -0.15 -0.05 0.15 -0.08 0.23 0.48 -0.19 0.64 0.02
4261 || orf19.7574 || || || Ortholog(s) have ubiquitin ligase complex localization || 1 1.09 1.08 0.67 0.38 1.81 1.63 0.02 -0.12 0.04 -0.17 0.04 0.44 0.13 -0.44 1.35 0.50
4262 || orf19.4133 || || || Protein wth a predicted role in transcription from RNA polymerase II promoters; Spider biofilm induced || 1 0.68 0.98 0.61 0.34 1.40 1.82 -0.05 0.01 0.04 -0.36 -0.20 0.22 0.41 -0.09 0.58 -0.18
4263 || orf19.6601.1 || YKE2 || || Possible heterohexameric Gim/prefoldin protein complex subunit; role in folding alpha-tubulin, beta-tubulin, and actin; transcript induced by yeast-to-hypha switch; regulated by Nrg1, Tup1; Spider and flow model biofilm induced || 1 2.13 1.70 0.75 0.61 2.95 2.68 0.90 0.32 -0.05 -0.09 0.35 -0.51 0.38 -0.79 1.52 -0.44
4264 || orf19.1482 || HSK3 || || Subunit of the Dam1 (DASH) complex, which acts in chromosome segregation by coupling kinetochores to spindle microtubules; expression regulated during planktonic growth || 1 1.26 0.98 0.48 0.67 1.52 1.10 0.26 0.10 0.08 -0.12 0.55 -0.16 0.27 0.07 0.60 -0.06
4265 || orf19.7225 || || || Ortholog of C. dubliniensis CD36 : Cd36_13150, C. parapsilosis CDC317 : CPAR2_700610, Candida tenuis NRRL Y-1498 : CANTEDRAFT_135418 and Debaryomyces hansenii CBS767 : DEHA2B01298g || 1 0.77 0.96 0.55 0.13 1.38 1.62 0.44 -0.49 -0.13 -0.17 0.12 -0.02 0.07 -0.59 0.62 0.36
4266 || orf19.7356 || || || Ortholog of C. parapsilosis CDC317 : CPAR2_807080, C. dubliniensis CD36 : Cd36_85690, Candida orthopsilosis Co 90-125 : CORT_0C02090 and Candida albicans WO-1 : CAWG_02885 || 1 1.32 1.59 1.36 0.96 0.60 1.32 0.48 0.23 0.04 -0.25 -0.04 0.12 1.05 -0.57 0.50 0.38
4267 || orf19.1203 || SRO77 || || Protein with a predicted role in docking and fusion of post-Golgi vesicles with the plasma membrane; filament induced; fungal-specific (no human or murine homolog) || 1 0.42 1.10 0.71 0.64 0.28 0.59 0.09 0.31 0.25 0.05 0.02 0.06 0.28 0.06 0.36 0.40
4268 || orf19.1386 || || || Ortholog(s) have SNAP receptor activity and role in ER to Golgi vesicle-mediated transport, retrograde vesicle-mediated transport, Golgi to ER, vesicle fusion || 1 0.61 0.57 0.81 0.74 0.77 0.59 -0.21 0.01 0.16 0.05 0.42 0.41 0.71 -0.27 0.11 0.20
4269 || orf19.4987 || NUP49 || || Nuclear pore protein || 1 0.53 0.42 0.50 0.46 0.89 0.56 -0.07 0.10 0.09 0.23 0.28 0.08 0.59 0.04 0.19 0.25
4270 || orf19.1525 || || || Ortholog(s) have role in nuclear-transcribed mRNA catabolic process, nonsense-mediated decay and cytoplasm, nucleus localization || 1 0.06 0.58 0.64 0.67 0.76 0.92 -0.17 -0.24 0.98 0.20 0.16 0.81 0.77 0.31 -0.23 0.44
4271 || orf19.2332 || || || Ortholog of C. parapsilosis CDC317 : CPAR2_210560, C. dubliniensis CD36 : Cd36_10180, Candida orthopsilosis Co 90-125 : CORT_0A09890 and Candida tropicalis MYA-3404 : CTRG_04072 || 1 0.39 0.38 0.25 0.26 0.66 0.89 0.09 -0.04 1.01 0.34 0.31 0.69 0.63 0.54 -0.28 0.35
4272 || orf19.4465 || || || Protein of unknown function; Spider biofilm induced || 1 0.70 0.91 0.72 0.49 0.93 1.51 0.55 0.22 1.28 0.45 -0.18 0.69 0.78 0.57 -0.08 0.81
4273 || orf19.2800 || || || Ortholog of Candida albicans WO-1 : CAWG_00667 || 1 0.64 1.10 1.12 0.60 1.37 0.88 0.20 0.48 1.13 0.50 0.07 0.97 1.04 -0.13 -0.07 0.86
4274 || orf19.7023 || || || Ortholog of S. cerevisiae Ioc4, a protein that influences gene expression through chromatin remodeling; oxidative stress-induced via Cap1 || 1 0.20 0.15 0.46 0.35 0.55 0.44 0.13 0.19 0.72 0.09 0.29 0.43 0.54 0.08 0.17 0.42
4275 || orf19.3528 || || || Protein of unknown function; Spider biofilm induced || 1 0.30 -0.03 0.33 0.58 0.73 0.60 0.15 0.55 0.47 0.41 0.49 0.40 0.81 -0.16 0.30 0.22
4276 || orf19.2971 || || || Ortholog of C. dubliniensis CD36 : Cd36_02630, C. parapsilosis CDC317 : CPAR2_108390, Candida tenuis NRRL Y-1498 : CANTEDRAFT_115724 and Debaryomyces hansenii CBS767 : DEHA2D07986g || 1 0.37 0.40 0.59 0.51 0.88 0.97 0.12 0.63 0.68 0.25 0.43 0.92 1.09 0.05 0.82 0.27
4277 || orf19.2201 || || || Ortholog(s) have ribosome binding activity, role in mitochondrial respiratory chain complex III assembly, positive regulation of mitochondrial translation and mitochondrial ribosome localization || 1 0.27 0.44 0.37 0.40 0.98 0.56 0.52 0.72 0.74 0.38 1.08 0.64 1.51 0.38 0.60 0.35
4278 || orf19.6726 || || || Ortholog(s) have DNA secondary structure binding activity || 1 -0.13 0.09 0.21 0.09 0.78 0.65 0.59 0.43 0.62 0.52 0.61 0.26 0.54 0.29 0.43 0.47
4279 || orf19.2863.1 || ERV1 || || Predicted component of the mitochondrial intermembrane space (IMS), involved in protein import into mitochondrial intermembrane space || 1 0.17 0.49 0.10 0.09 0.86 0.75 0.28 0.33 0.85 0.40 0.51 0.48 0.68 0.27 0.63 0.41
4280 || orf19.3600 || || || Protein of unknown function; flow model biofilm induced || 1 0.35 0.57 0.64 0.37 1.03 1.56 0.62 0.86 1.12 0.49 0.93 0.57 1.05 0.23 0.24 0.26
4281 || orf19.6827 || SLU7 || || Protein similar to S. cerevisiae RNA splicing factor, Slu7; induced by alpha pheromone in SpiderM medium || 1 -0.31 0.39 0.38 0.04 1.09 1.32 0.35 0.54 0.61 0.57 0.54 0.64 0.60 0.25 0.53 0.07
4282 || orf19.1953 || || || Predicted protein of unknown function; merged with orf19.1952 in Assembly 21 || 1 0.04 0.27 0.25 0.10 1.05 0.80 0.18 0.46 0.35 -0.03 0.23 0.58 0.71 0.24 0.51 0.09
4283 || orf19.4455 || || || Protein of unknown function; Spider biofilm induced || 1 0.33 0.37 0.32 0.37 0.61 1.14 0.67 0.20 0.92 0.57 0.30 0.37 1.04 0.57 0.62 0.05
4284 || orf19.4766 || ARG81 || || Zn(II)2Cys6 transcription factor; required for utilization of ornithine as a nitrogen source and for wild-type resistance to caffeine; required for yeast cell adherence to silicone substrate || 1 0.16 0.40 0.53 0.22 0.54 0.50 0.41 0.34 0.62 0.16 0.14 0.06 0.69 -0.02 0.31 0.14
4285 || orf19.5241 || SNT1 || || Ortholog of S. cerevisiae Snt1; an NAD-independent histone deacetylase; heterozygous transposon mutation affects filamentous growth; null mutants are viable || 1 0.32 0.65 0.56 0.09 0.90 0.75 0.10 0.34 0.33 -0.12 -0.07 0.04 0.91 0.31 0.43 0.13
4286 || orf19.3568 || RXT3 || || Putative transcriptional repressor || 1 0.61 0.76 0.62 0.34 1.14 1.19 0.29 0.01 0.52 0.13 0.55 -0.07 1.38 0.48 0.39 0.28
4287 || orf19.606 || || || Protein of unknown function; Hap43-induced; Spider biofilm induced || 1 0.31 0.46 0.37 0.52 0.85 0.16 0.20 0.18 0.31 0.21 0.20 0.15 0.91 0.49 0.62 0.05
4288 || orf19.7604 || || || Ortholog(s) have Rab guanyl-nucleotide exchange factor activity || 1 0.26 0.73 1.03 0.90 0.98 0.47 0.02 0.34 0.54 0.19 0.09 0.19 1.04 0.38 0.25 -0.29
4289 || orf19.4123 || || || Putative THO complex subunit; possibly an essential gene, disruptants not obtained by UAU1 method; protein newly produced during adaptation to the serum || 1 0.18 0.44 0.59 0.58 0.56 0.56 0.01 0.24 0.29 -0.02 0.41 0.17 0.68 0.40 0.42 0.06
4290 || orf19.2605 || PRK1 || || Putative protein serine/threonine kinase; mutants sensitive to growth on hydrogen peroxide medium || 1 0.47 0.88 0.89 0.75 1.20 0.92 0.46 0.33 1.12 0.06 0.57 0.58 1.22 0.64 0.63 0.34
4291 || orf19.4312 || || || Ortholog(s) have TBP-class protein binding, transcription cofactor activity || 1 0.51 1.07 1.14 0.70 1.31 0.65 0.31 0.46 1.24 0.34 0.46 0.47 1.57 0.59 0.51 0.01
4292 || orf19.1545 || || || Ortholog(s) have structural constituent of ribosome activity and mitochondrial small ribosomal subunit localization || 1 0.24 0.68 0.89 0.20 0.86 0.75 0.21 0.38 0.84 0.22 0.37 0.59 1.04 0.12 0.30 -0.27
4293 || orf19.4374 || PRP42 || || Putative component of the U1 snRNP, involved in splicing; ortholog of S. cerevisiae PRP42 || 1 0.50 0.54 0.58 0.30 0.79 0.47 0.37 0.38 0.55 0.44 0.34 0.15 0.87 0.33 0.50 -0.46
4294 || orf19.367 || CNH1 || || Na+/H+ antiporter; required for wild-type growth, cell morphology, and virulence in a mouse model of systemic infection; not transcriptionally regulated by NaCl; fungal-specific (no human or murine homolog) || 1 0.92 1.19 0.85 0.85 1.63 1.38 0.41 0.45 0.69 0.59 0.71 0.36 1.46 0.84 1.07 -0.39
4295 || orf19.6953 || IRS4 || || Protein with roles in cell wall integrity, systemic (but not oral) murine infection, adherence, hyphal growth, and agar-embedded filamentous growth; antigenic in human infection; similar to S. cerevisiae Irs4p || 1 0.40 0.42 0.71 0.52 0.62 0.65 0.20 0.19 0.47 0.31 0.14 0.44 0.71 0.42 0.55 -0.38
4296 || orf19.3907 || || || Ortholog of Candida albicans WO-1 : CAWG_04797 || 1 0.82 0.52 1.66 1.09 1.36 0.85 0.91 0.45 0.47 0.76 0.80 0.01 2.12 0.21 1.01
4297 || orf19.4499 || RIM2 || || Putative mitochondrial carrier protein; induced by alpha pheromone in SpiderM medium; Spider biofilm induced || 1 0.18 0.27 0.68 0.37 0.55 0.66 0.07 0.20 0.41 0.53 -0.13 0.14 0.62 0.55 0.31 -0.17
4298 || orf19.4204 || || || Ortholog(s) have structural constituent of ribosome activity and mitochondrial small ribosomal subunit localization || 1 0.63 0.73 0.74 0.62 0.90 0.80 0.28 0.50 0.95 1.18 0.19 0.47 0.99 0.50 0.65 -0.10
4299 || orf19.6967 || USO6 || || Putative vesicular transport protein; transcript induced by filamentous growth; rat catheter biofilm repressed || 1 0.86 0.80 0.80 0.97 0.78 1.30 -0.01 0.41 0.77 1.36 0.45 0.56 1.02 0.80 0.60 0.21
4300 || orf19.3998 || || || Ortholog(s) have Atg8 ligase activity, protein binding, bridging activity and role in C-terminal protein lipidation, CVT pathway, macroautophagy, mitochondrion degradation, piecemeal microautophagy of nucleus || 1 0.89 0.96 0.60 1.09 1.27 1.21 -0.18 0.33 0.87 0.88 0.00 1.15 1.02 0.68 0.81 0.28
4301 || orf19.6102 || RCA1 || || Protein involved in regulation of carbonic anhydrases; controls CO2 sensing; bZIP domain-containing transcription factor of the ATF/CREB family; null mutant displays slow growth, abnormal colony morphology and invasive growth || 1 0.08 0.33 0.53 0.25 0.89 1.19 0.08 0.19 0.68 0.39 0.52 0.06 0.27 0.40 0.11 0.41
4302 || orf19.1954 || PUS4 || || Putative pseudouridine synthase; transcript regulated by Nrg1, Mig1, and Tup1 || 1 0.17 0.41 0.76 0.18 0.85 0.78 0.26 0.09 0.29 0.17 0.25 -0.18 0.44 0.35 0.24 0.25
4303 || orf19.1953 || || || Predicted protein of unknown function; merged with orf19.1952 in Assembly 21 || 1 -0.01 0.23 0.75 0.21 0.79 0.85 0.11 0.29 0.32 -0.01 0.18 0.37 0.61 0.47 0.14 0.22
4304 || orf19.3945 || || || Predicted COP9 signalosome complex subunit 12; flow model biofilm induced || 1 -0.18 0.04 0.60 0.04 0.55 0.53 0.20 0.03 0.26 0.08 0.01 0.23 0.38 0.31 0.14 0.45
4305 || orf19.3862 || || || Putative intracellular transport protein; heterozygous null mutant displays sensitivity to rapamycin; expression upregulated during growth in the mouse cecum || 1 0.22 0.34 0.38 -0.06 0.72 0.61 0.14 0.24 0.12 -0.11 0.19 0.04 -0.07 0.32 0.42 0.07
4306 || orf19.1338 || || || Protein of unknown function; possible COPI-coated vesicle, Golgi apparatus, ribosome localization; rat catheter biofilm repressed || 1 0.34 0.34 0.06 -0.02 0.68 0.54 0.07 0.32 0.17 -0.05 -0.01 0.09 -0.06 0.03 0.08 -0.05
4307 || orf19.2742 || || || Ortholog of C. parapsilosis CDC317 : CPAR2_400095, C. dubliniensis CD36 : Cd36_42560, Candida tenuis NRRL Y-1498 : CANTEDRAFT_113280 and Lodderomyces elongisporus NRLL YB-4239 : LELG_04166 || 1 0.65 0.50 0.36 0.63 1.44 0.41 0.72 0.93 0.73 0.27 0.74 -0.13 0.40 -0.08 0.20 0.14
4308 || orf19.2731 || || || Ortholog of Debaryomyces hansenii CBS767 : DEHA2E16016g, Pichia stipitis Pignal : PICST_38487, Spathaspora passalidarum NRRL Y-27907 : SPAPADRAFT_58603 and Candida tropicalis MYA-3404 : CTRG_00248 || 1 0.89 0.57 0.60 0.50 1.29 0.40 0.42 1.05 0.51 0.24 0.53 0.21 -0.16 -0.11 0.18 0.47
4309 || orf19.540 || || || Has domain(s) with predicted palmitoyl-(protein) hydrolase activity and role in cellular protein modification process || 1 0.73 0.42 0.69 0.87 0.72 0.40 0.39 1.41 0.52 -0.03 0.90 0.37 0.06 0.49 0.17 1.00
4310 || orf19.764 || || || Ortholog(s) have clathrin-coated vesicle, cytoplasm localization || 1 0.74 0.42 0.21 0.40 0.43 0.37 0.18 -0.04 0.63 0.15 0.52 0.48 0.30 0.51 0.61 0.76
4311 || orf19.1353 || || || Protein of unknown function; repressed by yeast-hypha switch; Ras1-regulated; oral infection induced; mutants defective in damage to oral epithelium; flow model biofilm induced; Spider biofilm induced || 1 0.63 0.45 0.14 0.17 0.90 0.49 -0.33 -0.26 0.57 0.51 0.70 0.66 0.74 0.76 0.26 0.96
4312 || orf19.1105 || || || Ortholog of C. parapsilosis CDC317 : CPAR2_302980, C. dubliniensis CD36 : Cd36_53630, Pichia stipitis Pignal : PICST_32155 and Candida orthopsilosis Co 90-125 : CORT_0E05120 || 1 0.73 0.60 0.00 -0.07 0.82 0.65 0.13 0.71 0.41 0.69 0.62 0.85 0.22 1.16 0.40 1.30
4313 || orf19.114 || || || Ortholog of C. dubliniensis CD36 : Cd36_61190, C. parapsilosis CDC317 : CPAR2_603230, Candida tenuis NRRL Y-1498 : cten_CGOB_00054 and Debaryomyces hansenii CBS767 : DEHA2E21142g || 1 0.19 0.55 -0.31 0.13 0.67 0.79 0.31 0.28 1.04 0.78 0.32 0.51 0.36 0.44 0.57 0.75
4314 || orf19.544 || RPR2 || || Ortholog(s) have ribonuclease P activity, role in intronic box C/D snoRNA processing and cytosol, nucleolar ribonuclease P complex localization || 1 0.41 0.21 0.49 -0.19 0.49 0.88 0.24 0.79 0.20 0.88 0.06 0.94 0.22 0.28 0.81 0.58
4315 || orf19.5875 || VAM3 || || Predicted target membrane receptor (t-SNARE) involved in vacuolar transport, endocytosis, and secretion; required for biofilm formation in RPMI-1640 and for virulence; rat catheter biofilm repressed || 1 -0.04 -0.38 0.41 0.21 0.20 0.44 0.12 0.77 0.33 1.19 0.58 0.72 -0.05 0.93 0.32 0.36
4316 || orf19.2305 || || || Ortholog(s) have tubulin binding activity, role in tubulin complex assembly and prefoldin complex localization || 1 0.34 0.01 0.10 0.64 0.29 0.56 0.36 0.99 0.09 1.16 0.52 0.76 0.28 0.90 0.58 0.58
4317 || orf19.7553 || || || Protein of unknown function; rat catheter biofilm repressed || 1 0.69 0.35 0.47 0.84 0.70 0.55 0.43 0.62 0.19 1.36 0.46 1.19 0.45 0.73 0.54 0.93
4318 || orf19.2201 || || || Ortholog(s) have ribosome binding activity, role in mitochondrial respiratory chain complex III assembly, positive regulation of mitochondrial translation and mitochondrial ribosome localization || 1 0.10 0.31 0.37 0.12 0.36 0.60 0.31 0.59 0.98 1.09 0.90 0.99 0.23 0.33 0.18 0.66
4319 || orf19.2201 || || || Ortholog(s) have ribosome binding activity, role in mitochondrial respiratory chain complex III assembly, positive regulation of mitochondrial translation and mitochondrial ribosome localization || 1 0.15 0.09 0.61 0.24 0.35 0.73 0.52 0.65 0.90 1.24 0.58 1.18 0.18 0.44 0.21 0.38
4320 || orf19.2201 || || || Ortholog(s) have ribosome binding activity, role in mitochondrial respiratory chain complex III assembly, positive regulation of mitochondrial translation and mitochondrial ribosome localization || 1 0.37 0.07 0.23 0.38 0.61 0.58 0.34 1.01 0.49 1.11 0.50 1.04 -0.23 0.24 0.40 0.46
4321 || orf19.2201 || || || Ortholog(s) have ribosome binding activity, role in mitochondrial respiratory chain complex III assembly, positive regulation of mitochondrial translation and mitochondrial ribosome localization || 1 0.07 0.17 0.21 0.20 0.21 0.46 0.09 0.81 0.50 0.90 0.57 0.86 -0.14 -0.09 0.31 0.38
4322 || orf19.6233 || || || Ortholog(s) have endoplasmic reticulum, nuclear envelope localization || 1 0.04 0.31 0.54 0.43 0.33 0.79 0.04 0.20 0.35 0.41 0.12 0.38 -0.08 -0.03 0.31 0.29
4323 || orf19.6239 || || || Putative serine/threonine protein kinase; possibly an essential gene, disruptants not obtained by UAU1 method || 1 0.13 0.26 0.44 0.31 0.40 0.72 0.04 0.30 0.21 0.45 0.14 0.50 -0.32 0.21 0.39 0.52
4324 || orf19.2282 || || || Has domain(s) with predicted catechol 1,2-dioxygenase activity, ferric iron binding activity and role in catechol-containing compound metabolic process, oxidation-reduction process || 1 0.32 0.15 0.66 0.25 0.37 1.17 0.08 0.26 0.73 0.51 0.30 0.52 0.14 0.51 0.43 0.81
4325 || orf19.897 || VPS20 || || ESCRT III complex protein; role in multivesicular body (MVB) trafficking; required for processing of Rim8; Bcr1-repressed in RPMI a/a biofilms || 1 0.38 0.58 0.75 0.75 0.49 0.83 0.17 0.13 0.33 0.12 0.28 1.01 0.13 0.72 0.93 1.06
4326 || orf19.1359 || || || Ortholog(s) have protein complex binding activity, role in ER-associated ubiquitin-dependent protein catabolic process, sporulation resulting in formation of a cellular spore and cytoplasm, extrinsic to membrane, nucleus localization || 1 0.22 0.47 0.33 0.63 0.47 0.53 0.18 0.06 0.52 0.82 0.15 0.74 0.00 0.71 0.63 0.75
4327 || orf19.6147 || || || Putative histone chaperone; role in chromatin remodeling; rat catheter and Spider biofilm repressed || 1 0.06 0.11 0.71 2.13 0.05 1.23 0.48 0.61 0.74 1.04 0.88 1.83 0.06 1.34 -0.03 0.96
4328 || orf19.2519 || || || Ortholog(s) have role in chromosome segregation and nuclear MIS12/MIND complex localization || 1 -0.17 0.31 0.66 0.41 0.22 0.45 0.13 0.29 0.25 0.37 0.47 0.66 0.18 0.63 -0.01 0.50
4329 || orf19.3163 || || || Ortholog of C. dubliniensis CD36 : Cd36_51910, C. parapsilosis CDC317 : CPAR2_101650, Candida tenuis NRRL Y-1498 : CANTEDRAFT_94797 and Debaryomyces hansenii CBS767 : DEHA2D06578g || 1 0.08 0.27 0.34 0.29 0.02 0.23 0.13 0.02 0.18 0.20 0.23 0.41 0.05 0.50 0.23 0.22
4330 || orf19.6319 || || || Ortholog(s) have mRNA binding, ubiquitin-specific protease activity and role in protein deubiquitination, regulation of ER to Golgi vesicle-mediated transport, regulation of response to osmotic stress, ribophagy || 1 -0.10 0.19 0.52 0.33 0.50 0.67 -0.01 0.06 0.67 0.61 0.19 0.60 0.63 0.59 0.39 0.50
4331 || orf19.5510 || || || Ortholog(s) have role in chromatin silencing at telomere, negative regulation of transcription from RNA polymerase II promoter by pheromones and CHRAC localization || 1 0.30 0.59 0.95 0.97 0.29 1.06 0.16 0.11 0.49 1.33 0.43 0.81 0.74 1.30 0.12 0.20
4332 || orf19.1900 || || || Ortholog(s) have RNA methyltransferase activity, role in 7-methylguanosine cap hypermethylation, meiosis, nucleologenesis, regulation of telomere maintenance via telomerase and nucleolus localization || 1 0.09 0.26 0.27 0.44 0.33 0.25 -0.00 0.15 0.09 0.29 0.23 0.28 0.33 0.38 0.24 -0.06
4333 || orf19.3627 || || || Ortholog of C. dubliniensis CD36 : Cd36_22640, C. parapsilosis CDC317 : CPAR2_406910, Candida tenuis NRRL Y-1498 : CANTEDRAFT_104937 and Debaryomyces hansenii CBS767 : DEHA2D02706g || 1 0.25 0.32 0.38 0.62 0.57 0.48 0.63 -0.01 0.57 1.26 0.33 0.05 0.29 0.41 0.62 0.19
4334 || orf19.4168 || || || Ortholog(s) have ribonuclease MRP activity, ribonuclease P activity, role in intronic box C/D snoRNA processing, mRNA cleavage and nucleolar ribonuclease P complex, ribonuclease MRP complex localization || 1 0.89 0.56 0.32 0.74 -0.00 1.41 0.56 0.17 0.80 1.15 0.52 0.28 -0.02 0.69 0.59 0.08
4335 || orf19.5308 || || || Protein of unknown function; induced by Rgt1 || 1 0.40 -0.31 0.27 0.37 1.04 0.63 0.82 1.18 0.83 0.12 0.25 0.66 0.65 0.51 0.38 0.71
4336 || orf19.1041 || || || Ortholog(s) have cyclin-dependent protein serine/threonine kinase activity || 1 0.40 0.25 0.36 0.52 0.17 0.40 0.49 1.52 0.13 0.27 0.89 0.49 0.50 -0.00 0.18 0.26
4337 || orf19.2539 || || || Protein of unknown function; transcript detected on high-resolution tiling arrays || 1 0.09 0.33 0.21 0.30 0.35 0.62 0.49 1.15 0.13 -0.17 0.32 0.54 0.25 0.98 0.39
4338 || orf19.4148 || || || Ortholog of C. dubliniensis CD36 : Cd36_50820, C. parapsilosis CDC317 : CPAR2_501670, Candida tenuis NRRL Y-1498 : CANTEDRAFT_115294 and Debaryomyces hansenii CBS767 : DEHA2E13464g || 1 0.17 0.13 0.38 0.42 0.60 0.60 0.00 0.84 0.20 -0.16 1.15 0.93 0.47 0.16 0.74 0.55
4339 || orf19.5630 || APA2 || || Putative ATP adenylyltransferase II; regulated by Gcn4; repressed by amino acid starvation (3-AT); induced by prostaglandins; Hap43-repressed; Spider biofilm repressed || 1 0.10 -0.07 0.30 0.29 0.01 0.76 0.65 0.66 0.87 -0.20 0.90 0.67 0.39 0.28 0.51 0.74
4340 || orf19.794 || SSN3 || || Putative cyclin-dependent protein kinase; mutants are sensitive to growth on H2O2 medium || 1 -0.01 0.01 0.11 -0.12 0.08 0.16 0.40 0.27 0.13 0.03 0.43 0.09 0.19 0.15 0.23 0.25
4341 || orf19.1778 || || || Dubious open reading frame || 1 1.49 0.76 0.44 0.31 1.71 1.09 1.06 0.38 0.20 -0.01 0.49 0.96 0.19 0.35 0.08 0.50
4342 || orf19.4964 || || || Ortholog(s) have role in cellular bud site selection, mRNA export from nucleus, mRNA splicing, via spliceosome and RES complex localization || 1 0.29 0.23 0.11 -0.04 0.99 0.99 0.32 0.07 -0.11 1.06 0.43 1.02 1.03 0.90 -0.46
4343 || orf19.3230 || BOI2 || || Putative SH3-domain-containing protein; mutation confers hypersensitivity to toxic ergosterol analog; Spider biofilm induced || 1 -0.08 0.22 -0.13 0.20 0.46 0.27 -0.01 0.33 0.21 0.62 0.26 0.32 0.40 0.43 0.73 0.01
4344 || orf19.5465 || || || Ortholog(s) have first spliceosomal transesterification activity, role in generation of catalytic spliceosome for first transesterification step and U2-type catalytic step 1 spliceosome, mitotic spindle pole body localization || 1 -0.10 0.06 -0.77 0.38 0.58 0.50 0.43 -0.05 0.15 0.70 0.28 0.56 0.89 1.32 -0.04
4345 || orf19.1228 || HAP2 || || CCAAT-binding transcription factor; regulates low-iron induction of FRP1; in these conditions CBF comprises Hap43 and probably Hap2 and Hap3; possibly essential, disruptants not obtained by UAU1 method; Cap1-dependent induction in low iron || 1 0.61 0.46 -0.15 0.19 0.37 0.09 0.48 0.59 -0.24 0.31 0.48 0.43 1.09 1.27 1.00 0.37
4346 || orf19.6027 || || || Ortholog of C. dubliniensis CD36 : Cd36_00740, C. parapsilosis CDC317 : CPAR2_110170, Candida tenuis NRRL Y-1498 : CANTEDRAFT_133175 and Debaryomyces hansenii CBS767 : DEHA2D09724g || 1 1.31 0.89 -0.22 -0.07 1.17 0.20 0.36 0.53 -0.04 0.82 1.12 1.25 1.31 0.86 0.56 0.85
4347 || orf19.1261 || CGT1 || || mRNA 5' guanylyltransferase; small subunit of mRNA capping enzyme; binds an RNA Pol II C-terminal domain peptide; Cet1p and Cgt1p form a 2:1 complex; functional homolog of S. cerevisiae Ceg1p || 1 0.53 0.31 0.08 -0.14 0.65 0.56 0.14 0.25 0.10 0.55 0.69 0.76 1.00 0.68 0.69 0.64
4348 || orf19.6227 || || || Ortholog of C. dubliniensis CD36 : Cd36_06390, C. parapsilosis CDC317 : CPAR2_209040, Candida tenuis NRRL Y-1498 : CANTEDRAFT_114052 and Debaryomyces hansenii CBS767 : DEHA2D14300g || 1 0.67 0.75 0.18 0.04 0.35 0.31 0.49 0.03 -0.35 1.06 0.54 0.85 1.56 0.49 0.88 0.28
4349 || orf19.6227 || || || Ortholog of C. dubliniensis CD36 : Cd36_06390, C. parapsilosis CDC317 : CPAR2_209040, Candida tenuis NRRL Y-1498 : CANTEDRAFT_114052 and Debaryomyces hansenii CBS767 : DEHA2D14300g || 1 0.65 0.83 -0.15 -0.02 0.76 0.59 0.40 0.26 -0.47 1.03 0.94 1.22 1.60 0.48 1.49 0.55
4350 || orf19.6227 || || || Ortholog of C. dubliniensis CD36 : Cd36_06390, C. parapsilosis CDC317 : CPAR2_209040, Candida tenuis NRRL Y-1498 : CANTEDRAFT_114052 and Debaryomyces hansenii CBS767 : DEHA2D14300g || 1 0.52 0.54 0.02 0.17 0.28 0.50 0.29 0.07 -0.31 0.60 0.53 0.86 1.21 0.19 1.00 -0.07
4351 || orf19.6227 || || || Ortholog of C. dubliniensis CD36 : Cd36_06390, C. parapsilosis CDC317 : CPAR2_209040, Candida tenuis NRRL Y-1498 : CANTEDRAFT_114052 and Debaryomyces hansenii CBS767 : DEHA2D14300g || 1 0.57 0.54 0.50 0.48 0.16 0.28 0.22 0.06 -0.62 0.64 0.42 0.58 1.33 -0.01 1.06 0.06
4352 || orf19.927 || || || Ortholog(s) have role in positive regulation of transcription from RNA polymerase II promoter, telomere maintenance and EKC/KEOPS complex, cytosol, nucleus localization || 1 0.25 0.26 0.18 -0.12 0.06 -0.01 0.31 0.07 0.15 0.28 0.25 0.40 0.72 0.24 0.30 -0.07
4353 || orf19.2823 || RFG1 || || HMG domain transcriptional repressor of filamentous growth and hyphal genes; in Tup1-dependent and -independent pathways; binds DNA; transcript not regulated by oxygen or serum; not responsible for hypoxic repression; Spider biofilm induced || 1 1.70 1.30 -0.03 0.26 -0.00 0.11 1.30 0.45 0.69 0.59 0.81 -0.17 1.54 -0.58 1.23 -0.44
4354 || orf19.2823 || RFG1 || || HMG domain transcriptional repressor of filamentous growth and hyphal genes; in Tup1-dependent and -independent pathways; binds DNA; transcript not regulated by oxygen or serum; not responsible for hypoxic repression; Spider biofilm induced || 1 1.54 1.36 0.12 0.61 0.12 0.04 0.96 0.28 0.56 0.44 0.75 0.19 1.42 -0.32 1.02 -0.14
4355 || orf19.3809 || BAS1 || || Putative Myb-like transcription factor; ortholog S. cerevisiae Bas1, a regulator of purine biosynthetic genes; mutant exhibits adenine auxotrophy and abnormal colony morphology || 1 0.92 0.60 0.56 0.23 0.47 0.45 0.31 -0.24 0.25 0.38 0.07 -0.00 1.30 -0.15 1.13 -0.38
4356 || orf19.232 || || || RNA polymerase II mediator complex subunit; possibly an essential gene, disruptants not obtained by UAU1 method || 1 0.99 0.60 0.19 0.29 0.30 0.18 0.15 0.40 -0.15 0.20 0.02 -0.31 1.48 -0.02 0.60 -0.43
4357 || orf19.177 || || || Has domain(s) with predicted phosphatidylinositol binding activity and role in cell communication || 1 0.40 0.48 0.22 0.64 0.37 0.08 -0.03 0.41 0.21 0.59 0.25 0.36 0.90 0.29 1.11 -0.25
4358 || orf19.1757 || || || Putative C2H2 transcription factor; expression upregulated in clinical isolates from HIV+ patients with oral candidiasis; Spider biofilm induced || 1 0.58 0.71 0.29 0.66 0.76 -0.05 0.09 0.12 -0.05 0.65 0.17 0.04 0.79 -0.15 0.58 -0.20
4359 || orf19.1757 || || || Putative C2H2 transcription factor; expression upregulated in clinical isolates from HIV+ patients with oral candidiasis; Spider biofilm induced || 1 1.08 1.42 0.75 1.16 0.81 0.32 0.39 0.45 0.20 1.12 0.54 0.48 1.27 0.09 0.72 -0.27
4360 || orf19.1757 || || || Putative C2H2 transcription factor; expression upregulated in clinical isolates from HIV+ patients with oral candidiasis; Spider biofilm induced || 1 0.92 0.85 0.50 0.71 0.30 0.00 -0.28 0.02 0.01 0.73 -0.04 0.44 0.87 -0.03 0.41 -0.56
4361 || orf19.5291 || || || Ortholog(s) have role in phospholipid biosynthetic process and endoplasmic reticulum localization || 1 0.71 0.79 0.49 0.64 0.43 -0.14 -0.06 0.03 0.29 0.32 0.12 0.60 0.44 -0.04 0.47 0.10
4362 || orf19.2752 || ADR1 || || C2H2 transcription factor; ortholog of S. cerevisiae Adr1 but mutant phenotype suggests a different set of target genes; transposon mutation affects filamentous growth; Spider biofilm induced || 1 0.85 1.07 0.60 0.67 0.58 0.13 -0.29 0.20 0.25 0.44 -0.07 0.58 0.37 0.36 0.66 0.07
4363 || orf19.6534 || || || Ortholog of Candida albicans WO-1 : CAWG_05537 || 1 0.91 0.09 0.34 0.66 0.27 0.50 0.31 0.16 0.24 0.25 0.56 0.62 -0.07 0.47 0.50 -0.01
4364 || orf19.4748 || || || Putative U2B'' component of the U2 snRNP, involved in splicing; contains an RNA recognition motif (RRM); ortholog of S. cerevisiae MSL1; Hap43p-induced gene || 1 0.15 0.15 0.45 0.56 0.58 0.11 -0.03 0.53 -0.04 0.47 0.80 0.76 0.38 0.54 -0.32 -0.28
4365 || orf19.7301 || || || Has domain(s) with predicted DNA binding activity || 1 0.18 0.30 0.15 0.47 0.73 0.08 0.66 0.86 0.58 0.79 0.69 0.95 0.81 1.30 -0.00 -0.61
4366 || orf19.1445 || ESC4 || || Protein similar to S. cerevisiae Esc4; a protein that represses transposition; transposon mutation affects filamentation; rat catheter biofilm repressed || 1 0.60 0.95 0.53 0.24 0.77 0.54 0.88 0.58 1.65 1.44 1.05 0.58 -0.34 -0.50
4367 || orf19.7453 || || || Ortholog of Candida albicans WO-1 : CAWG_02974 || 1 0.70 1.18 0.04 0.40 0.74 -0.23 0.93 0.97 0.46 1.44 1.06 0.17 0.76 0.91 0.11 -0.25
4368 || orf19.6583 || || || Protein of unknown function; induced by alpha pheromone in SpiderM medium || 1 1.62 2.08 0.04 -0.06 1.01 -0.36 1.29 0.24 0.42 1.45 0.47 1.38 1.83 -0.31 -0.59
4369 || orf19.5835 || || || Ortholog(s) have role in rRNA processing, ribosomal small subunit assembly and CURI complex, UTP-C complex, cytosol localization || 1 0.15 0.29 -0.12 -0.23 0.29 0.42 0.39 0.19 0.02 0.62 0.99 0.53 0.57 0.30 -0.09 -0.41
4370 || orf19.3658 || || || Ortholog(s) have role in protein folding in endoplasmic reticulum and Golgi apparatus, integral to endoplasmic reticulum membrane, mitochondrion localization || 1 0.20 0.60 0.49 0.60 0.65 0.71 0.28 1.44 0.44 -0.43 0.44 -0.19 1.13 0.37 0.60 0.26
4371 || orf19.68.2 || || || Ortholog of C. dubliniensis CD36 : Cd36_11670, C. parapsilosis CDC317 : CPAR2_201750, Candida tenuis NRRL Y-1498 : CANTEDRAFT_115679 and Debaryomyces hansenii CBS767 : DEHA2E16940g || 1 0.14 0.94 0.31 -0.27 0.83 0.15 -0.08 0.35 0.41 0.12 0.69 -0.23 0.21 0.52 0.21 0.24
4372 || orf19.68.2 || || || Ortholog of C. dubliniensis CD36 : Cd36_11670, C. parapsilosis CDC317 : CPAR2_201750, Candida tenuis NRRL Y-1498 : CANTEDRAFT_115679 and Debaryomyces hansenii CBS767 : DEHA2E16940g || 1 0.61 0.84 0.13 -0.06 0.48 0.48 0.24 0.25 -0.21 -0.09 0.34 -0.28 0.39 0.62 0.23 0.23
4373 || orf19.68.2 || || || Ortholog of C. dubliniensis CD36 : Cd36_11670, C. parapsilosis CDC317 : CPAR2_201750, Candida tenuis NRRL Y-1498 : CANTEDRAFT_115679 and Debaryomyces hansenii CBS767 : DEHA2E16940g || 1 0.65 0.62 0.23 0.00 0.60 0.83 -0.33 -0.06 -0.00 0.06 0.34 -0.18 0.35 1.00 0.13 0.38
4374 || orf19.68.2 || || || Ortholog of C. dubliniensis CD36 : Cd36_11670, C. parapsilosis CDC317 : CPAR2_201750, Candida tenuis NRRL Y-1498 : CANTEDRAFT_115679 and Debaryomyces hansenii CBS767 : DEHA2E16940g || 1 0.59 0.54 0.31 0.17 0.30 0.44 -0.23 0.00 0.03 0.13 0.62 -0.30 0.11 1.01 0.08 0.12
4375 || orf19.68.2 || || || Ortholog of C. dubliniensis CD36 : Cd36_11670, C. parapsilosis CDC317 : CPAR2_201750, Candida tenuis NRRL Y-1498 : CANTEDRAFT_115679 and Debaryomyces hansenii CBS767 : DEHA2E16940g || 1 0.46 0.49 0.72 0.35 0.64 0.83 -0.08 0.05 -0.02 -0.01 0.75 -0.18 0.13 0.96 0.36 0.16
4376 || orf19.4803 || || || Ortholog of Candida albicans WO-1 : CAWG_00488 || 1 1.09 1.04 1.22 0.28 1.13 0.54 -0.70 0.42 0.29 0.59 0.56 0.31 1.08 0.59
4377 || orf19.2379 || NOT4 || || Putative E3 ubiquitin-protein ligase; required for maintenance, but not induction, of hyphal development; homozygous null mutant is avirulent in mouse systemic infection despite persistence in host; repressed in rat oral candidiasis || 1 0.53 0.38 0.87 0.65 0.32 0.06 0.24 0.22 0.38 0.31 0.28 0.22 0.28 -0.11 0.96 0.40
4378 || orf19.6280 || || || Dubious open reading frame || 1 0.41 1.14 3.29 0.30 0.93 0.80 0.26 0.91 0.00 1.18 -0.46 1.30 1.76
4379 || orf19.4502 || || || Ortholog(s) have ATPase activity, DNA binding, TBP-class protein binding activity || 1 0.17 0.38 1.54 0.71 0.55 0.48 0.60 0.17 0.58 -0.21 0.87 0.31 0.93 0.38 0.68 0.50
4380 || orf19.2609 || CET1 || || mRNA 5'-triphosphatase; large subunit of mRNA capping enzyme; positively regulates Ceg1 activity; functional homolog of S. cerevisiae Cet1; Cet1 and Cgt1 form a 2:1 complex; flow model biofilm induced || 1 -0.01 0.08 0.56 0.15 0.23 0.37 -0.09 0.27 -0.07 0.03 0.05 -0.04 0.43 0.08 0.39 0.20
4381 || orf19.2957 || || || Protein required for transfer of mannosylphosphate; induced by alpha pheromone in SpiderM medium || 1 -0.08 -0.34 0.83 0.23 0.37 0.20 -0.12 0.64 0.20 0.04 0.15 -0.25 0.25 0.13 0.59 0.88
4382 || orf19.7274 || || || Predicted ORF in retrotransposon Zorro2 with similarity to retroviral reverse transcriptase proteins || 1 0.53 0.32 0.90 -0.01 0.59 0.87 0.39 1.01 0.00 0.32 0.30 -0.46 0.49 -0.03 0.90 1.05
4383 || orf19.5231 || || || Protein of unknown function; flow model biofilm induced || 1 0.61 0.46 0.98 0.20 0.41 0.14 0.20 0.70 0.44 0.42 -0.11 -0.39 0.24 0.18 1.24 1.07
4384 || orf19.5935 || || || Ortholog of C. dubliniensis CD36 : Cd36_84710, C. parapsilosis CDC317 : CPAR2_807470, Candida tenuis NRRL Y-1498 : CANTEDRAFT_136475 and Debaryomyces hansenii CBS767 : DEHA2B08844g || 1 0.27 0.30 0.50 0.18 0.35 0.09 -0.01 0.25 0.03 -0.17 -0.20 -0.04 0.32 0.06 0.33 0.32
4385 || orf19.653 || || || Dubious open reading frame || 1 0.74 0.18 0.81 0.31 1.66 0.20 0.44 0.59 -0.07 0.01 -0.10 0.19 0.21 0.52 0.81 0.32
4386 || orf19.991 || DJP1 || || Similar to bacterial DnaJ; reported to have a role in peroxisome biogenesis; induced in low iron and upon adherence to polystyrene || 1 0.14 0.05 0.53 0.12 0.64 0.37 0.20 0.29 -0.11 0.30 0.11 -0.04 -0.04 -0.04 0.42 0.23
4387 || orf19.4592 || HSX11 || || UDP-glucose:ceramide glucosyltransferase (glucosylceramide synthase [GCS], EC 2.4.1.80); involved in glucosylceramide biosynthesis, which is important for virulence || 1 0.17 0.26 0.54 0.43 1.13 0.38 0.61 0.37 0.23 0.40 0.48 -0.19 0.78 -0.11 0.10 -0.70
4388 || orf19.4983 || || || Ortholog of C. dubliniensis CD36 : Cd36_12520, C. parapsilosis CDC317 : CPAR2_201720, Candida tenuis NRRL Y-1498 : CANTEDRAFT_108003 and Debaryomyces hansenii CBS767 : DEHA2D05214g || 1 0.54 0.46 0.42 -0.09 1.21 0.81 0.96 0.47 0.64 0.18 0.97 -0.06 1.04 0.04 0.41 -0.29
4389 || orf19.2430 || || || Ortholog of Candida albicans WO-1 : CAWG_00792 || 1 0.81 0.14 0.67 1.10 1.16 1.05 -0.15 -0.33 1.78 -0.50 1.79 0.67 0.83
4390 || orf19.5551 || MIF2 || || Centromere-associated protein; similar to CENP-C proteins; Cse4p and Mif2p colocalize at C. albicans centromeres || 1 0.27 0.19 0.62 0.68 0.79 0.33 0.31 -0.22 0.01 0.20 0.47 -0.31 0.70 0.72 0.07 -0.19
4391 || orf19.5551 || MIF2 || || Centromere-associated protein; similar to CENP-C proteins; Cse4p and Mif2p colocalize at C. albicans centromeres || 1 0.45 0.50 0.56 0.76 0.86 0.06 0.09 -0.02 -0.17 0.08 0.50 -0.61 0.41 0.67 0.40 0.17
4392 || orf19.2398 || || || Protein of unknown function; Hap43-repressed; transcript increased in azole-resistant strain overexpressing CDR1 and CDR2; possibly regulated by Tac1; induced by Mnl1 in weak acid stress; flow model biofilm induced; Spider biofilm induced || 1 0.46 0.66 0.74 0.60 0.78 -0.07 0.75 0.17 0.35 -0.05 0.56 -0.68 0.95 0.92 0.58 0.69
4393 || orf19.3049 || || || Ortholog(s) have protein kinase activity, role in activation of bipolar cell growth, ascospore wall assembly, protein phosphorylation and cell division site, cytosol, nucleus, prospore membrane localization || 1 -0.18 1.08 0.76 0.91 1.33 -0.72 0.24 0.55 0.29 -0.18 0.77 0.26 0.53 0.62 0.55 -0.21
4394 || orf19.4672 || || || Ortholog of Candida albicans WO-1 : CAWG_03665 || 1 0.93 1.05 0.77 1.16 2.03 -0.96 0.60 0.50 0.84 -0.20 0.77 -0.40 0.89 1.06 0.36 -0.91
4395 || orf19.2612 || || || C2H2 zinc finger transcription factor; expression reduced in ssr1 null mutant; flow model biofilm induced || 1 0.93 0.82 1.03 0.98 1.52 -0.52 0.65 0.68 0.31 0.09 0.55 -0.31 1.10 0.32 0.47 -0.23
4396 || orf19.5335 || SGS1 || || RecQ-related DNA helicase; Bloom's syndrome-related gene; haploinsufficient for wild-type lifespan; upregulated in farnesol treated biofilm || 1 0.60 0.63 0.43 0.38 0.64 -0.18 0.32 0.59 0.16 0.03 0.16 -0.52 0.37 0.03 0.01 -0.28
4397 || orf19.7453 || || || Ortholog of Candida albicans WO-1 : CAWG_02974 || 1 0.50 2.59 1.03 1.19 1.36 0.67 0.54 0.38 0.67 0.26 0.84 0.10 0.52 0.61 -0.01 -0.01
4398 || orf19.5498 || EFH1 || || APSES transcription factor; homodimer; minor role in transcriptional regulation vs Efg1; regulates filamentous growth, phenotypic switch; EFG1 and EFH1 genetically interact; expression interferes with mouse intestinal tract colonization || 1 1.08 1.06 0.53 0.13 1.16 -0.81 0.38 -0.02 0.48 -0.32 -0.01 -0.65 0.48 0.17 0.46 0.25
4399 || orf19.1146 || || || Ortholog of Candida albicans WO-1 : CAWG_00265 || 1 0.11 0.23 0.24 -0.01 -0.20 -0.15 0.28 0.15 -0.04 -0.36 0.67 0.28 0.95 0.09 0.21 0.88
4400 || orf19.1146 || || || Ortholog of Candida albicans WO-1 : CAWG_00265 || 1 0.53 0.22 -0.04 -0.25 0.02 -0.14 0.50 0.18 -0.14 -0.27 0.97 0.14 1.26 0.08 0.35 0.61
4401 || orf19.3714 || || || Ortholog of C. dubliniensis CD36 : Cd36_33530, C. parapsilosis CDC317 : CPAR2_201980, Candida tenuis NRRL Y-1498 : CANTEDRAFT_134293 and Debaryomyces hansenii CBS767 : DEHA2A10164g || 1 0.38 0.31 0.11 0.02 0.20 -0.32 0.12 0.29 -0.38 -0.27 0.42 -0.04 0.83 0.54 0.44 0.07
4402 || orf19.4457 || BNI4 || || Protein required for wild-type cell wall chitin distribution, morphology, hyphal growth; not essential; similar to S. cerevisiae Bni4p (targeting subunit for Glc7p phosphatase, involved in bud-neck localization of chitin synthase III) || 1 0.79 0.69 -0.10 0.09 0.44 -0.25 0.57 0.16 -0.06 0.02 0.26 -0.49 0.69 0.52 0.04 0.22
4403 || orf19.3550 || SGO1 || || Component of the spindle checkpoint; cell-cycle regulated periodic mRNA expression || 1 0.91 0.98 0.24 0.12 0.75 -0.36 1.02 0.69 -0.38 -0.31 0.87 -0.01 1.34 0.82 0.05 0.63
4404 || orf19.5596 || || || Ortholog(s) have ASTRA complex localization || 1 1.19 0.69 0.44 0.59 0.65 -0.36 0.95 0.29 -0.62 0.01 1.25 -0.69 0.93 0.25 0.60
4405 || orf19.2230 || || || Putative pre-mRNA-splicing factor; decreased transcription is observed upon benomyl treatment || 1 0.46 0.26 0.35 0.19 0.41 -0.30 0.23 0.35 -0.23 0.24 0.35 -0.08 0.37 0.13 0.31 0.08
4406 || orf19.6530 || || || Similar to bacterial DnaJ; transcript upregulated in low iron; flow model biofilm induced; Spider biofilm induced || 1 0.57 0.72 0.44 -0.33 0.66 0.00 0.81 0.01 -0.42 0.54 1.06 -0.33 1.18 0.33 0.64 1.10
4407 || orf19.794 || SSN3 || || Putative cyclin-dependent protein kinase; mutants are sensitive to growth on H2O2 medium || 1 0.46 0.52 0.33 -0.19 0.56 -0.08 0.54 0.19 -0.08 -0.21 1.10 0.02 0.67 0.17 0.76 0.62
4408 || orf19.3359 || ARP8 || || Putative chromatin-remodeling enzyme complex protein; mutation confers hypersensitivity to toxic ergosterol analog, and to amphotericin B; rat catheter biofilm induced || 1 0.50 0.68 -0.25 -0.01 0.29 0.01 0.50 0.46 -0.51 -0.26 0.67 -0.08 0.36 0.12 0.49 0.56
4409 || orf19.3685 || PSY2 || || Putative protein phosphatase PP4 complex subunit; macrophage-induced gene || 1 0.38 0.35 0.34 -0.04 0.53 -0.11 0.14 0.20 -0.44 -0.13 0.42 0.54 0.39 0.26 0.42 0.61
4410 || orf19.1387 || || || Ortholog(s) have 4 iron, 4 sulfur cluster binding activity, role in iron-sulfur cluster assembly, tRNA wobble uridine modification and cytoplasm localization || 1 0.42 0.45 0.30 0.10 0.65 0.02 -0.07 -0.06 0.05 -0.38 0.46 -0.01 0.47 0.02 0.47 0.49
4411 || orf19.3677 || || || Ortholog(s) have Atg8 ligase activity and role in C-terminal protein lipidation, CVT pathway, ascospore formation, cellular response to nitrogen starvation, macroautophagy, mitochondrion degradation, piecemeal microautophagy of nucleus || 1 0.56 0.42 0.11 -0.07 0.60 0.31 0.21 0.15 -0.18 -0.52 0.11 0.25 0.20 0.08 0.16 0.70
4412 || orf19.6030 || || || Protein of unknown function; transcript detected on high-resolution tiling arrays || 1 0.61 0.57 0.00 -0.12 0.41 0.12 0.28 0.16 -0.26 -0.25 0.20 0.14 0.07 -0.09 0.06 0.35
4413 || orf19.3615 || || || Protein of unknown function; induced in core caspofungin response; expression upregulated in an ssr1 null mutant; induced by nitric oxide independent of Yhb1p || 1 0.77 0.87 -0.10 -0.12 0.42 -0.09 0.90 0.25 -0.07 -0.71 0.60 0.23 0.14 0.10 1.10 0.63
4414 || orf19.3615 || || || Protein of unknown function; induced in core caspofungin response; expression upregulated in an ssr1 null mutant; induced by nitric oxide independent of Yhb1p || 1 0.49 0.80 0.21 0.16 0.50 0.21 0.61 0.19 0.20 -0.47 0.65 0.36 0.15 0.69 0.88 1.05
4415 || orf19.6280 || || || Dubious open reading frame || 1 1.15 1.49 0.29 0.09 -0.22 0.61 0.16 0.52 -0.85 1.25 0.59 1.61
4416 || orf19.4523 || || || Ortholog(s) have 5-formyltetrahydrofolate cyclo-ligase activity, role in folic acid-containing compound biosynthetic process and mitochondrion localization || 1 0.65 0.39 0.19 -0.12 0.41 -0.12 0.57 0.12 -0.11 -0.34 0.53 0.20 -0.12 -0.29 0.15 1.18
4417 || orf19.524 || || || Ortholog(s) have role in mitotic sister chromatid segregation and cytosol, nucleus localization || 1 0.46 0.30 0.20 0.19 0.42 -0.00 0.19 0.29 0.13 -0.14 0.44 0.22 -0.13 0.01 0.23 0.72
4418 || orf19.6602 || || || Ortholog(s) have role in aerobic respiration, ubiquinone biosynthetic process and mitochondrial inner membrane localization || 1 0.82 0.58 0.19 -0.22 0.12 0.39 0.08 0.48 0.26 -0.18 1.03 0.35 0.33 0.17 0.58 0.52
4419 || orf19.3000 || ORC1 || || Putative origin recognition complex large subunit; essential for viability; similar to S. cerevisiae Orc1p origin recognition complex subunit || 1 0.23 0.18 -0.06 -0.21 0.40 -0.32 0.22 0.21 -0.04 -0.03 0.13 -0.09 0.16 0.09 0.25 0.29
4420 || orf19.1360.1 || || || Putative adhesin-like protein || 1 1.22 1.15 -0.35 -0.67 0.58 -0.34 1.11 1.69 -0.74 -0.43 1.64 -0.16 0.77 -0.47 0.94 -0.17
4421 || orf19.131.2 || || || Ortholog(s) have endoplasmic reticulum localization || 1 0.63 0.48 -0.06 0.02 0.43 0.22 0.38 0.63 -0.42 -0.39 0.31 -0.07 0.20 -0.54 0.10 0.01
4422 || orf19.5642 || || || Ortholog of S. cerevisiae Dif1; which regulates nuclear localization of Rnr2 and Rnr4; colony morphology-related gene regulation by Ssn6; induced in cyr1 mutant; Spider biofilm induced || 1 0.67 0.50 0.13 -0.10 0.13 0.05 0.28 0.12 -0.13 -0.92 0.43 -0.33 0.81 -0.69 0.33 0.05
4423 || orf19.1509 || ROD1 || || Protein similar to S. cerevisiae Rod1;a membrane protein with a role in drug tolerance; repressed by Rgt1; mutant is viable || 1 1.02 1.04 -0.42 -0.34 0.02 0.16 0.65 -0.05 -0.17 -0.42 0.37 -0.29 0.83 -0.16 0.37 0.09
4424 || orf19.7204 || || || Ortholog(s) have glyoxysome localization || 1 0.94 0.89 0.17 0.83 0.32 0.17 0.86 0.79 -0.29 -0.63 0.12 -0.63 0.09 0.37 0.93 0.40
4425 || orf19.5312 || MET4 || || Putative transcription coactivator; predicted role in sulfur amino acid metabolism; required for yeast cell adherence to silicone substrate; Spider biofilm induced || 1 0.60 0.57 -0.20 0.44 -0.49 -0.01 0.38 0.41 -0.83 -0.78 0.78 -0.47 1.03 0.39 1.46 0.34
4426 || orf19.5312 || MET4 || || Putative transcription coactivator; predicted role in sulfur amino acid metabolism; required for yeast cell adherence to silicone substrate; Spider biofilm induced || 1 0.82 0.69 0.05 1.05 -0.34 0.18 0.15 0.52 -0.54 -0.61 0.55 -0.36 0.78 0.19 1.21 0.66
4427 || orf19.5312 || MET4 || || Putative transcription coactivator; predicted role in sulfur amino acid metabolism; required for yeast cell adherence to silicone substrate; Spider biofilm induced || 1 0.92 0.84 0.34 0.96 -0.06 0.30 0.48 0.58 -0.58 -0.32 0.94 0.04 1.00 0.81 1.32 0.49
4428 || orf19.5312 || MET4 || || Putative transcription coactivator; predicted role in sulfur amino acid metabolism; required for yeast cell adherence to silicone substrate; Spider biofilm induced || 1 0.40 0.46 0.43 0.91 -0.37 0.19 0.02 0.37 -0.39 -0.23 0.49 0.15 0.68 0.80 1.24 0.38
4429 || orf19.5522 || || || Ortholog of C. dubliniensis CD36 : Cd36_62760, C. parapsilosis CDC317 : CPAR2_601700, Candida tenuis NRRL Y-1498 : CANTEDRAFT_115220 and Debaryomyces hansenii CBS767 : DEHA2A06666g || 1 0.48 0.53 0.28 0.50 0.03 0.34 -0.10 0.40 -0.74 -0.28 1.30 1.07 -0.56 -0.13 0.38 0.47
4430 || orf19.3517 || || || Ortholog(s) have Dsc E3 ubiquitin ligase complex, endoplasmic reticulum, fungal-type vacuole lumen localization || 1 0.90 0.37 -0.14 0.17 0.62 0.12 -0.29 0.13 -0.46 -0.10 0.79 0.00 -0.29 -0.72 0.69 -0.17
4431 || orf19.3319 || || || Putative thioredoxin; Spider biofilm repressed || 1 0.32 0.21 -0.09 -0.04 0.51 0.18 -0.42 0.17 -0.19 -0.01 0.80 0.46 -0.49 -0.52 0.55 0.34
4432 || orf19.6820 || || || Has domain(s) with predicted protein heterodimerization activity, role in DNA-dependent transcription, initiation and transcription factor TFIID complex localization || 1 0.17 0.24 -0.02 -0.14 0.20 0.00 0.11 -0.03 -0.15 -0.27 0.53 0.40 -0.01 -0.34 0.71 0.42
4433 || orf19.3886 || || || Ortholog of C. dubliniensis CD36 : Cd36_31820, C. parapsilosis CDC317 : CPAR2_205050, Debaryomyces hansenii CBS767 : DEHA2G10736g and Pichia stipitis Pignal : PICST_32993 || 1 0.42 0.57 0.19 0.26 0.27 0.38 0.04 0.50 -0.44 0.08 0.65 0.78 0.46 -0.59 0.77 0.91
4434 || orf19.2419 || || || Ortholog of S. cerevisiae Dom34; a protein that facilitates ribosomal subunit dissociation when translation is stalled; peloto ortholog; Hap43-repressed gene || 1 0.50 0.42 0.12 -0.35 0.65 0.70 0.16 0.70 0.15 0.12 0.89 0.49 -0.04 -0.55 0.84 0.56
4435 || orf19.2067 || || || Protein with a predicted role in mitochondrial iron metabolism; Hap43-repressed; expression upregulated during growth in the mouse cecum; Spider biofilm induced || 1 0.39 0.24 0.65 0.25 0.71 1.14 0.40 0.01 0.15 0.51 1.02 0.92 -0.52 -0.88 0.94 0.35
4436 || orf19.7183 || || || Ortholog(s) have role in protein folding in endoplasmic reticulum and ER membrane protein complex localization || 1 0.40 0.33 0.43 0.47 0.65 0.55 0.10 0.33 0.16 0.19 0.64 0.47 -0.15 -0.23 0.72 0.31
4437 || orf19.6551 || || || Ortholog(s) have SNAP receptor activity, role in Golgi vesicle transport, vesicle fusion and Golgi medial cisterna, SNARE complex localization || 1 0.88 0.93 0.18 0.24 0.91 0.65 0.41 0.18 0.03 0.21 0.97 0.61 -0.15 -0.29 1.18 0.11
4438 || orf19.2939 || || || Ortholog(s) have mitochondrion localization || 1 0.70 0.66 0.22 0.17 0.90 0.65 -0.05 0.22 -0.30 0.59 1.36 0.71 -0.57 -0.37 1.60 0.44
4439 || orf19.2939 || || || Ortholog(s) have mitochondrion localization || 1 0.32 0.50 0.36 0.38 0.28 0.41 -0.08 0.10 -0.18 0.35 0.80 0.48 -0.48 -0.21 0.50 -0.06
4440 || orf19.4412 || || || Ortholog(s) have DNA-directed DNA polymerase activity, deoxycytidyl transferase activity and role in error-free translesion synthesis, error-prone translesion synthesis || 1 -0.02 0.61 0.27 0.29 0.74 0.25 0.13 -0.28 0.27 0.15 0.58 0.54 -0.09 -0.29 0.58 0.25
4441 || orf19.7421 || CYP5 || || Putative peptidyl-prolyl cis-trans isomerase; macrophage-downregulated protein level; protein level decrease in stationary phase cultures; predicted endoplasmic reticulum (ER) localization || 1 0.29 0.39 0.38 0.51 0.17 0.09 -0.01 0.02 0.16 -0.09 0.23 0.30 0.21 -0.04 0.71 -0.24
4442 || orf19.1225 || PEX22 || || Putative peroxin || 1 0.78 0.73 1.08 1.53 0.76 0.22 -0.01 -0.03 -0.41 0.24 0.88 0.29 0.49 -0.32 1.12 0.26
4443 || orf19.1225 || PEX22 || || Putative peroxin || 1 0.56 0.45 0.33 1.12 0.21 0.09 -0.21 0.10 -0.69 -0.05 0.82 0.10 0.41 -1.00 1.14 0.01
4444 || orf19.2108 || SOD6 || || Copper- and zinc-containing superoxide dismutase; gene family includes SOD1, SOD4, SOD5, and SOD6; gene may contain an intron; Hap43-repressed; flow model and rat catheter biofilm induced || 1 0.86 0.47 -0.25 1.58 0.87 -0.09 0.09 -0.14 0.61 0.17 1.02 0.91 0.55 0.03 1.21
4445 || orf19.3529 || ABP2 || || Putative alpha-actinin-like protein; induced by alpha pheromone in SpiderM medium || 1 0.64 0.24 0.50 0.84 0.49 -0.07 0.55 0.43 0.81 -0.55 1.09 0.63 -0.91 -0.10 1.43
4446 || orf19.7176 || NPT1 || || Putative nicotinate phosphoribosyltransferase, involved in NAD salvage pathway; fungal-specific (no human or murine homolog) || 1 0.41 0.42 0.22 0.18 0.27 0.02 -0.12 0.13 0.22 -0.22 0.38 0.51 0.28 -0.23 0.12 0.94
4447 || orf19.4322 || DAP2 || || Putative dipeptidyl aminopeptidase; transcriptionally regulated during macrophage response || 1 0.31 0.19 0.23 0.32 0.15 -0.04 -0.27 -0.15 0.22 0.08 0.38 0.81 0.01 -0.29 0.20 0.50
4448 || orf19.3050 || AGE1 || || Putative GTPase activator; induced in low iron; rat catheter biofilm repressed || 1 0.03 0.03 0.54 0.65 0.45 0.46 -0.11 0.20 0.16 -0.01 0.35 0.48 0.03 -0.16 0.33 0.84
4449 || orf19.2505 || || || Ortholog of Candida albicans WO-1 : CAWG_02437 || 1 -0.26 -0.16 0.41 0.64 -0.00 0.63 0.30 0.75 0.89 0.38 -0.58 0.23 0.98
4450 || orf19.5677 || DUR4 || || Putative urea permease; fungal-specific (no human or murine homolog); possibly an essential gene, disruptants not obtained by UAU1 method || 1 0.13 0.27 0.43 0.79 0.36 0.05 -0.10 0.51 -0.05 0.38 0.34 0.01 -0.14 -0.21 -0.14 0.53
4451 || orf19.2071 || || || Protein of unknown function; induced by alpha pheromone in SpiderM medium || 1 0.27 0.41 0.61 0.71 0.42 -0.34 0.10 0.49 -0.05 -0.17 0.38 0.27 -0.01 -0.41 0.17 0.44
4452 || orf19.2783 || PIR32 || || Cell wall protein, putative structural component of the cell wall; mutation leads to increased chitin content, increased virulence and resistance to stresses; macrophage-induced gene || 1 0.27 0.28 0.94 0.85 0.76 -0.24 -0.09 0.36 -0.48 0.15 0.25 0.15 -0.16 -0.45 -0.15 0.64
4453 || orf19.2505 || || || Ortholog of Candida albicans WO-1 : CAWG_02437 || 1 0.67 0.57 0.97 -0.15 -0.10 0.45 -0.45 0.12 0.26 0.09 0.30 0.76
4454 || orf19.1634 || || || Has domain(s) with predicted fatty-acyl-CoA binding activity || 1 0.28 0.37 0.50 0.69 0.44 0.03 -0.24 0.07 -0.11 -0.41 0.25 0.25 0.14 -0.28 0.21 0.29
4455 || orf19.4867 || SWE1 || || Putative protein kinase with a role in control of growth and morphogenesis, required for full virulence; mutant cells are small, rounded, and sometimes binucleate; not required for filamentous growth; mutant is hypersensitive to caspofungin || 1 -0.28 0.19 0.67 0.42 0.52 -0.25 -0.20 -0.03 -0.08 -0.28 0.41 0.31 -0.01 0.22 0.14 0.44
4456 || orf19.4134 || || || Ortholog(s) have palmitoyltransferase activity, role in protein palmitoylation and plasma membrane localization || 1 -0.11 0.08 0.66 0.52 0.59 0.05 0.13 0.01 0.04 -0.21 0.35 0.33 0.20 -0.03 0.52 0.36
4457 || orf19.7295 || || || Ortholog(s) have protein phosphatase 1 binding activity, role in actin filament organization, cortical actin cytoskeleton organization, endocytosis, protein secretion and actin cortical patch, nucleus localization || 1 -0.14 -0.05 0.50 0.24 0.23 -0.30 0.23 0.25 0.17 0.01 0.22 0.27 0.15 -0.16 0.59 0.32
4458 || orf19.4183 || MUC1 || || Protein similar to S. cerevisiae Muc1; a cell surface glycoprotein involved in filamentous growth; repressed by benomyl treatment; mutant is viable || 1 -0.02 -0.02 0.34 -0.07 0.32 0.28 0.24 0.11 0.40 -0.20 -0.08 0.26 -0.09 0.13 0.43 0.34
4459 || orf19.2933 || || || Ortholog(s) have ubiquitin-specific protease activity, role in protein deubiquitination, regulation of transcription, DNA-dependent and cytosol, nucleus localization || 1 -0.15 -0.10 0.14 0.48 0.21 0.36 0.10 0.11 0.16 0.23 0.11 0.67 -0.49 0.05 0.46 0.39
4460 || orf19.5943 || || || Ortholog(s) have role in peroxisome organization and peroxisomal membrane localization || 1 0.50 0.13 0.38 0.75 0.50 0.15 0.13 0.29 0.21 0.25 -0.14 0.86 -0.06 -0.35 1.00 0.72
4461 || orf19.2791 || BBC1 || || Putative SH3-domain-containing protein || 1 0.14 -0.11 0.12 0.24 0.53 0.24 0.16 0.07 0.25 -0.18 -0.01 0.56 -0.26 -0.08 0.57 0.66
4462 || orf19.130 || || || Ortholog(s) have protein serine/threonine kinase activity, ubiquitin binding activity || 1 0.52 0.44 0.25 0.30 0.81 0.93 -0.06 -0.13 0.09 -0.26 0.03 0.72 -0.27 0.27 0.58 1.00
4463 || orf19.3030 || || || Ortholog(s) have phosphatidylinositol binding activity || 1 0.28 0.08 0.12 0.21 0.67 0.80 -0.13 0.15 -0.06 -0.85 -0.01 0.38 -0.04 -0.04 0.72 1.10
4464 || orf19.6797 || || || Ortholog of C. dubliniensis CD36 : Cd36_86960, C. parapsilosis CDC317 : CPAR2_808800, Candida tenuis NRRL Y-1498 : CANTEDRAFT_113621 and Debaryomyces hansenii CBS767 : DEHA2F02486g || 1 0.08 -0.04 0.18 0.23 0.38 0.25 0.05 0.28 -0.13 -0.39 0.23 0.41 -0.04 -0.19 0.32 0.48
4465 || orf19.1638 || || || Has domain(s) with predicted zinc ion binding activity, role in ER to Golgi vesicle-mediated transport, intracellular protein transport and COPII vesicle coat localization || 1 0.03 0.07 -0.14 -0.14 0.34 0.61 -0.10 -0.44 0.34 -0.14 -0.00 0.57 -0.07 -0.32 0.50 0.70
4466 || orf19.1667 || || || Protein with a predicted SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily domain; Hap43-repressed gene || 1 -0.08 -0.18 -0.08 -0.07 0.46 0.64 0.16 -0.17 0.73 0.06 -0.25 0.86 0.19 -0.50 0.74 0.34
4467 || orf19.1636 || STE50 || || Protein with sterile alpha motif (SAM) and Ras-associated domain (RAD); similar to S. cerevisiae Rad50p, which is involved in signal transduction via interaction with and regulation of MAPKKK || 1 0.21 -0.15 0.22 0.05 0.67 0.55 -0.28 0.04 0.28 -0.15 0.17 0.49 0.28 -0.42 0.85 0.41
4468 || orf19.4614 || || || Adapter protein for pexophagy and the cytoplasm-to-vacuole targeting (Cvt) pathway; Spider biofilm induced || 1 0.39 0.28 0.15 -0.06 0.94 0.61 -0.43 -0.44 0.34 -0.07 -0.16 0.72 -0.08 -0.24 0.81 -0.12
4469 || orf19.2057 || || || Ortholog(s) have ATP binding, ATPase activity, metallopeptidase activity, role in protein complex assembly, proteolysis, signal peptide processing and m-AAA complex, mitochondrial inner boundary membrane localization || 1 0.20 0.15 -0.19 -0.19 0.72 0.74 0.56 0.42 1.01 0.51 -0.22 0.16 -0.03 -0.15 0.58 0.46
4470 || orf19.2463 || PRN2 || || Protein similar to pirin; Hap43p-repressed gene || 1 0.16 0.04 -0.12 -0.04 0.18 0.67 0.49 0.54 0.78 0.29 0.16 0.56 0.24 -0.46 0.78 0.67
4471 || orf19.4332 || || || Ortholog of C. dubliniensis CD36 : Cd36_52800, C. parapsilosis CDC317 : CPAR2_303110, Candida tenuis NRRL Y-1498 : CANTEDRAFT_92321 and Debaryomyces hansenii CBS767 : DEHA2G07964g || 1 0.23 0.03 0.18 0.04 0.03 0.56 0.42 0.39 0.64 0.51 0.05 0.48 0.39 -0.14 0.41 0.58
4472 || orf19.5908 || TEC1 || || TEA/ATTS transcription factor; white cell pheromone response, hyphal gene regulation; required for Spider and RPMI biofilm formation; regulates BCR1; Cph2 regulated transcript; alkaline, rat catheter, Spider, flow model biofilm induced || 1 -0.13 0.66 -0.12 0.16 -0.15 0.36 0.37 0.24 0.24 -0.11 0.65 0.33 0.46 -0.08 0.70 0.41
4473 || orf19.7024 || || || Ortholog of Candida albicans WO-1 : CAWG_05448 || 1 -0.18 1.07 0.14 0.28 -0.25 -0.06 0.31 0.50 0.62 -0.17 0.31 0.28 0.26 -0.48 0.56 0.34
4474 || orf19.7421 || CYP5 || || Putative peptidyl-prolyl cis-trans isomerase; macrophage-downregulated protein level; protein level decrease in stationary phase cultures; predicted endoplasmic reticulum (ER) localization || 1 0.02 0.04 0.10 0.28 -0.33 -0.09 0.08 0.06 0.04 -0.01 0.34 0.17 0.03 -0.49 0.62 0.14
4475 || orf19.4112 || || || Ortholog(s) have 8-oxo-dGDP phosphatase activity, ATP binding, magnesium ion binding, thiamine binding, thiamine diphosphokinase activity, role in thiamine biosynthetic process and cytosol localization || 1 0.19 0.32 0.19 0.19 -0.19 -0.22 0.31 0.16 0.19 0.14 0.50 -0.07 0.08 -0.21 0.72 -0.29
4476 || orf19.6942 || ORC3 || || Protein similar to S. cerevisiae Orc3p, which is a component of the origin recognition complex involved in DNA replication; mutation confers hypersensitivity to toxic ergosterol analog; induced under hydroxyurea treatment || 1 -0.05 0.12 0.10 0.22 0.39 -0.41 0.31 0.44 -0.02 -0.16 -0.08 0.26 0.31 -0.00 0.33 0.16
4477 || orf19.1821 || || || Protein of unknown function; repressed by alpha pheromone in SpiderM medium || 1 -0.45 0.16 -0.91 0.65 0.47 -0.58 1.27 0.90 -0.32 0.06 0.06 0.05 0.47 -0.75 0.43 0.60
4478 || orf19.7080 || LEU2 || || Isopropyl malate dehydrogenase; leucine biosynthesis; induced by human whole blood or PMNs; protein level decreases in stationary phase; GlcNAc-induced protein; flow model biofilm repressed || 1 -0.47 -0.46 0.10 0.50 -0.00 -0.74 0.89 0.55 0.24 0.22 0.34 -0.10 0.29 -0.24 0.34 -0.18
4479 || orf19.2289 || ARP3 || || Protein with Myo5p-dependent localization to cortical actin patches at hyphal tip; mutation confers hypersensitivity to cytochalasin D; Spider biofilm repressed || 1 -0.37 -0.40 -0.26 -0.40 0.22 -0.18 0.26 0.23 0.26 -0.31 0.59 0.31 -0.14 -0.51 -0.00 0.18
4480 || orf19.3722 || || || Predicted protein of rapamycin resistance; Spider biofilm induced || 1 -0.36 -0.08 -0.21 -0.42 0.32 -0.43 0.30 0.09 0.33 -0.30 0.26 0.36 0.17 -0.50 0.08 -0.12
4481 || orf19.7157 || || || Protein with a tubulin binding cofactor C domain; flow model biofilm induced || 1 -0.44 -0.41 -0.69 -0.07 0.59 -0.68 0.39 0.20 -0.13 -0.15 0.24 0.12 0.38 -0.20 -0.44 0.39
4482 || orf19.6313 || MNT4 || || Predicted alpha-1,3-mannosyltransferase with a role in protein glycosylation; induced in low iron || 1 -0.47 -0.23 -0.35 -0.04 0.45 -0.45 0.31 0.32 0.36 0.14 -0.11 0.14 0.27 0.06 0.38 -0.30
4483 || orf19.2033 || PGA19 || || Putative GPI-anchored protein; macrophage-induced gene; mutants are viable || 1 -0.14 -0.52 -0.43 -0.23 0.73 -0.86 0.24 0.44 0.73 -0.31 0.50 0.23 0.46 0.10
4484 || orf19.3885 || || || Has domain(s) with predicted N-acetyltransferase activity; highly induced during chlamydospore formation in both C. albicans and C. dubliniensis || 1 0.62 -0.44 -0.12 0.09 1.02 -1.27 0.32 0.74 0.89 0.06 0.49 0.32 0.56 0.52 0.12 0.04
4485 || orf19.3699 || TEP1 || || Putative protein phosphatase of the PTP family (tyrosine-specific), similar to S. cerevisiae Tep1p || 1 0.32 0.46 -0.26 -0.61 0.39 -0.29 0.16 0.63 0.23 -0.18 0.48 0.64 -0.14 0.11 0.19 0.31
4486 || orf19.2529 || || || Ortholog of S. cerevisiae Gpa15; involved in the synthesis of glycosylphosphatidylinositol (GPI) anchors; shuman Pig-H, which is also involved in GPI assembly; Spider biofilm induced || 1 0.25 0.18 -0.17 -0.37 0.61 -0.31 0.25 0.34 0.06 -0.37 0.57 0.35 0.07 0.19 -0.24 0.25
4487 || orf19.6832 || || || Protein of unknown function; regulated by Sef1p-, Sfu1p-, and Hap43p || 1 0.15 0.20 -0.47 -0.55 0.35 -0.51 0.07 0.15 0.01 -0.54 0.39 -0.03 0.74 0.23 0.05 0.64
4488 || orf19.4672 || || || Ortholog of Candida albicans WO-1 : CAWG_03665 || 1 -0.53 0.26 -0.24 -0.89 1.10 -1.63 -0.04 0.40 0.16 0.56 0.42 0.83 1.45
4489 || orf19.4596 || || || Protein of unknown function; Spider biofilm induced || 1 -0.23 -0.42 -0.38 -0.54 0.82 -0.37 0.06 0.21 0.06 -0.29 0.50 -0.09 0.23 -0.23 0.40 0.74
4490 || orf19.3512 || CSP1 || || Putative cell wall associated protein; gene only found in C. albicans and C. dubliniensis; highly upregulated during chlamydospore development in both species; localized to chlamydospore cell wall || 1 0.23 0.12 -0.23 -0.37 0.20 -0.47 0.27 0.32 -0.04 -0.53 0.03 -0.06 -0.31 0.04 0.38 0.64
4491 || orf19.5284 || || || Dubious open reading frame || 1 -0.03 0.15 -0.50 -0.14 -0.02 -0.69 0.26 0.61 0.26 -0.34 0.09 0.24 -0.28 0.20 0.29 0.60
4492 || orf19.6017 || || || Protein of unknown function; Spider biofilm induced || 1 0.37 -0.12 -0.44 -1.08 -0.31 -1.64 0.58 0.54 -0.36 -1.19 0.42 1.14 0.08 -0.36 0.73 -0.79
4493 || orf19.7609 || PGA11 || || Putative GPI-anchored protein || 1 -0.14 0.82 -0.14 -0.45 -0.59 -0.64 0.32 0.08 0.33 -0.08 -0.23 0.28 0.53 0.50 -0.24
4494 || orf19.3942 || || || Ortholog(s) have structural molecule activity || 1 -0.13 0.23 -0.28 -0.22 -0.16 -0.55 0.15 0.14 -0.21 -0.01 0.05 0.04 0.17 0.04 0.47 0.08
4495 || orf19.1077 || ATM1 || || Member of MDR subfamily of ABC family; ortholog of S. cerevisiae ABC transporter, Atm1; induced in low iron; induced by nitric oxide independent of Yhb1 || 1 -1.36 0.52 -0.71 -0.64 -0.29 -1.31 1.42 0.61 0.28 -0.73 0.30 -0.33 0.18 0.18 0.05 0.15
4496 || orf19.3950 || MSM1 || || Mitochondrial methionyl-tRNA synthetase (MetRS); functionally complements methionine auxotrophy of an E. coli MetRS mutant; transcript regulated by Nrg1; flow model biofilm induced || 1 -0.41 0.49 -0.43 -0.48 0.28 -0.60 0.05 0.38 0.25 0.33 -0.14 0.12 -0.14 -0.25 0.14 -0.12
4497 || orf19.5924 || ZCF31 || || Zn(II)2Cys6 transcription factor of unknown function; mutant is sensitive to copper and SDS, and resistant to Calcofluor White; required for yeast cell adherence to silicone substrate || 1 0.04 0.31 -0.76 -0.43 0.16 0.04 0.59 0.13 0.10 0.22 -0.73 0.19 0.12 0.39 -0.05 0.16
4498 || orf19.104 || || || Protein of unknown function; induced by alpha pheromone in SpiderM medium || 1 0.50 -0.59 -1.44 -0.26 -0.87 -1.37 1.13 1.08 0.69 0.88 -1.43 0.33 1.23
4499 || orf19.728 || TSC11 || || Protein similar to S. cerevisiae Tsc11p which is involved in sphingolipid biosynthesis; transposon mutation affects filamentous growth || 1 0.15 -0.05 -0.42 -0.37 -0.29 -0.52 0.41 0.16 0.19 -0.10 -0.12 0.32 -0.08 0.47 0.03 0.28
4500 || orf19.2033 || PGA19 || || Putative GPI-anchored protein; macrophage-induced gene; mutants are viable || 1 0.08 -0.47 -0.36 -1.76 -0.08 -0.50 -0.36 0.06 -0.46 0.71 -0.11 0.60 -0.20 0.56 -0.44 0.23
4501 || orf19.7192 || || || Ortholog of Candida albicans WO-1 : CAWG_05720 || 1 1.79 -0.44 0.14 -3.36 0.86 -0.41 -0.23 0.20 0.11 -0.14 1.60 -0.42 -0.27 0.29
4502 || orf19.2725 || || || Ortholog of Candida albicans WO-1 : CAWG_03525 || 1 1.36 0.16 -0.73 -3.60 0.82 -0.50 0.57 0.77 0.33 0.77 0.84 0.25 1.61 0.03 0.57
4503 || orf19.5717 || || || Ortholog of Candida albicans WO-1 : CAWG_05019 || 1 0.27 0.55 -0.58 1.10 -0.50 0.14 1.02 -0.23 -0.09 -0.25 -0.12 0.41 1.42 0.41 0.36
4504 || orf19.3231 || CDC27 || || Putative ubiquitin-protein ligase; periodic mRNA expression, peak at cell-cycle S/G2 phase || 1 0.32 0.37 -0.24 -0.17 -0.02 -0.45 0.13 0.51 0.08 0.31 -0.12 0.25 -0.10 0.58 0.26 0.46
4505 || orf19.3456 || || || Protein with a predicted serine/threonine kinase and tyrosine kinase domain; possibly an essential gene, disruptants not obtained by UAU1 method || 1 0.34 0.46 -0.87 -0.48 -0.21 -0.83 0.17 0.34 0.24 0.23 0.06 0.32 0.58 1.27 0.54 0.80
4506 || orf19.4253 || || || Ortholog(s) have role in negative regulation of gluconeogenesis, proteasome-mediated ubiquitin-dependent protein catabolic process, regulation of nitrogen utilization, vacuolar protein catabolic process || 1 0.12 0.27 -0.20 -0.44 0.23 -0.22 0.23 0.37 0.26 -0.08 0.14 0.50 0.23 0.66 0.35 0.52
4507 || orf19.1371 || || || Ortholog of C. dubliniensis CD36 : Cd36_23880, C. parapsilosis CDC317 : CPAR2_806590, Candida tenuis NRRL Y-1498 : CANTEDRAFT_92769 and Debaryomyces hansenii CBS767 : DEHA2B13376g || 1 0.12 0.14 -0.08 -0.39 0.00 -0.31 0.18 0.40 0.17 -0.23 0.00 0.08 0.26 0.33 0.25 0.37
4508 || orf19.3456 || || || Protein with a predicted serine/threonine kinase and tyrosine kinase domain; possibly an essential gene, disruptants not obtained by UAU1 method || 1 0.45 0.28 -0.06 -1.41 0.05 -1.93 0.17 1.03 -0.22 0.26 0.53 -0.07 0.69 1.08 0.66 0.81
4509 || orf19.218 || BUD20 || || Protein similar to S. cerevisiae Bud20p, which affects bud site selection; transposon mutation affects filamentous growth || 1 -0.07 -0.18 0.08 -1.21 0.17 0.19 0.16 0.80 -0.27 -0.09 0.12 0.38 0.57 0.52 0.43
4510 || orf19.1215 || || || Ortholog of C. dubliniensis CD36 : Cd36_64550, Candida tropicalis MYA-3404 : CTRG_02747 and Candida albicans WO-1 : CAWG_04972 || 1 0.31 0.05 -0.30 -1.26 -0.07 0.34 1.31 -0.31 -0.17 0.04 0.25 0.50 0.72 0.03
4511 || orf19.4310 || || || Dubious open reading frame || 1 0.21 -0.32 -0.19 -1.29 -0.19 -0.15 0.36 0.77 0.14 -0.90 0.42 0.66 0.41 1.42 0.51 0.03
4512 || orf19.3457 || SWD3 || || Ortholog(s) have histone methyltransferase activity (H3-K4 specific) activity, role in chromatin silencing at telomere, histone H3-K4 methylation, telomere maintenance and Set1C/COMPASS complex localization || 1 0.09 -0.07 0.07 -0.48 -0.25 0.06 0.06 0.10 0.22 -0.12 0.01 0.44 -0.04 0.55 0.42 0.00
4513 || orf19.3530 || CKA2 || || Catalytic alpha-subunit of protein kinase CK2; interaction with calcineurin pathway affects fluconazole sensitivity; synthetically lethal with CKA1; attenuated virulence in a mouse oropharyngeal candidiasis but not in a systemic mouse model || 1 0.01 -0.13 -0.20 -0.61 -0.32 -0.12 0.45 0.16 -0.25 0.38 0.05 0.21 0.18 0.69 0.17 -0.13
4514 || orf19.2800 || || || Ortholog of Candida albicans WO-1 : CAWG_00667 || 1 0.75 0.21 -0.82 -1.08 0.46 0.42 0.24 -0.26 0.64 -0.22 0.25 0.41 1.39 -0.19 -0.17
4515 || orf19.6012 || || || Ortholog(s) have cell division site, cell tip, cytosol localization || 1 0.29 0.20 -0.12 -0.15 0.01 -0.38 0.28 0.33 0.00 0.30 -0.21 0.16 0.01 0.42 -0.26 0.00
4516 || orf19.7551 || ALO1 || || D-Arabinono-1,4-lactone oxidase involved in biosynthesis of dehydro-D-arabinono-1,4-lactone, which has a protective role against oxidative damage; plasma membrane-localized;required for full virulence in a mouse model of systemic infection || 1 0.28 0.25 -0.56 -0.92 0.16 -0.10 0.55 0.40 0.51 0.01 0.17 -0.32 0.23 0.19 -0.44 0.24
4517 || orf19.163 || PAN6 || || Ortholog(s) have pantoate-beta-alanine ligase activity, role in pantothenate biosynthetic process and cytosol, nucleus localization || 1 0.14 0.22 -0.41 -1.38 0.12 0.40 0.67 0.40 0.57 0.23 -0.61 -0.42 0.67 -0.22 0.19 -0.09
4518 || orf19.4871 || ERO1 || || Ortholog of S. cerevisiae Ero1; role in formation of disulfide bonds in the endoplasmic reticulum; fluconazole-induced; induced by Mnl1 under weak acid stress; Spider biofilm induced || 1 0.31 0.22 0.22 -0.66 0.26 0.38 0.60 0.25 0.33 0.11 -0.13 -0.06 0.19 0.14 0.04 -0.02
4519 || orf19.3719 || || || Dubious open reading frame || 1 -0.21 -0.40 0.18 -1.10 0.06 0.10 -0.10 0.84 -0.34 0.12 0.65 0.59 0.27 0.01 -0.37
4520 || orf19.1995 || MNN24 || || Alpha-1,2-mannosyltransferase; required for normal cell wall mannan content || 1 0.23 0.15 -0.61 -0.99 -0.37 -0.24 0.38 0.20 0.41 -0.50 0.21 0.17 0.66 -0.10 -0.00 -0.32
4521 || orf19.1995 || MNN24 || || Alpha-1,2-mannosyltransferase; required for normal cell wall mannan content || 1 -0.04 -0.07 -0.44 -0.99 -0.61 -0.29 0.51 0.33 0.75 -0.06 0.19 0.62 0.63 0.18 0.07 -0.26
4522 || orf19.1496 || || || Putative transcription factor with zinc finger DNA-binding motif; Hap43p-repressed gene || 1 -0.23 -0.41 -0.76 -0.79 -0.73 -0.15 0.81 0.45 0.95 -0.07 -0.47 0.41 0.53 0.12 0.44 -0.42
4523 || orf19.4866 || CPP1 || || VH1 family MAPK phosphatase; regulates Cst20-Hst7-Cek1-Cph1 filamentation pathway; represses yeast-hyphal switch; required for virulence in mice; yeast-enriched; induced by alpha pheromone in SpiderM medium; Spider biofilm induced || 1 0.01 0.11 -0.17 -0.26 -0.14 -0.56 0.15 0.05 0.00 -0.07 -0.07 0.17 0.61 0.74 0.09 -0.00
4524 || orf19.1724 || || || Protein of unknown function; induced by nitric oxide independent of Yhb1p || 1 0.67 -0.23 -0.96 -0.45 -0.95 0.88 0.28 0.12 -1.33 3.47 0.78 -0.05
4525 || orf19.6309 || MSS11 || || Transcription factor; activator that binds to Flo8 via a LisH motif to cooperatively activate transcription of hypha-specific genes; required for hyphal growth || 1 -0.05 -0.38 -0.53 0.01 -0.02 -0.04 0.91 0.18 -0.04 0.02 0.09 0.34 2.15 0.94 0.95 0.02
4526 || orf19.3603 || MFG1 || || Regulator of filamentous growth; required for biofilm formation, virulence; interacts with Flo8 and Mss11 || 1 0.05 0.06 -0.07 -0.29 0.15 0.25 0.41 0.37 0.13 0.05 0.45 0.22 1.20 0.63 0.77 -0.32
4527 || orf19.5134 || || || Ortholog of C. parapsilosis CDC317 : CPAR2_704140, C. dubliniensis CD36 : Cd36_72870, Lodderomyces elongisporus NRLL YB-4239 : LELG_05208 and Candida orthopsilosis Co 90-125 : CORT_0G04320 || 1 0.50 0.65 -0.52 -0.17 0.69 0.33 1.12 -0.22 0.22 0.31 0.10 1.40 0.40 0.53
4528 || orf19.3280 || || || Ortholog of Candida albicans WO-1 : CAWG_01435 || 1 -0.22 0.46 0.07 -0.72 0.14 0.29 -0.05 0.16 -0.25 0.08 0.82 -0.31 -0.17 0.77
4529 || orf19.5486 || || || Putative endoribonuclease; heterozygous null mutant exhibits hypersensitivity to parnafungin and cordycepin in the C. albicans fitness test || 1 -0.24 -0.33 -0.09 -0.59 0.32 -0.40 0.22 0.02 -0.05 -0.09 0.22 -0.10 1.08 -0.01 -0.07 0.24
4530 || orf19.3522 || || || Protein of unknown function; flow model biofilm induced; transcript repressed by ciclopirox olamine || 1 -0.52 -0.24 -0.19 0.21 -0.29 -0.16 0.54 0.26 -0.10 1.05 -0.04 -0.19
4531 || orf19.2115 || || || Putative molybdopterin-converting factor; fungal-specific (no human or murine homolog) || 1 -0.02 0.22 0.68 0.07 0.44 -0.09 0.08 0.34 0.33 0.59 0.12 0.29 0.89 0.16 0.17 0.08
4532 || orf19.5184 || || || Putative Ran guanyl-nucleotide exchange factor; probable signal transducer; Spider biofilm repressed || 1 0.03 0.34 0.44 0.08 0.42 -0.24 -0.05 0.21 0.47 0.18 0.12 0.34 0.55 0.45 -0.01 0.00
4533 || orf19.3214 || || || Alpha/beta-HydrolasE superfamily protein; membrane-localized || 1 0.05 0.38 0.33 -0.12 0.41 -0.58 0.10 -0.02 0.19 0.35 -0.21 0.41 1.06 0.62 0.13 0.13
4534 || orf19.6252 || || || Ortholog(s) have RNA polymerase II transcription factor binding transcription factor activity, core RNA polymerase II binding transcription factor activity || 1 0.01 0.05 0.05 -0.18 -0.10 -0.10 -0.29 -0.18 0.19 0.24 -0.08 0.16 0.32 0.19 -0.06 0.02
4535 || orf19.4461 || || || Ortholog of Candida albicans WO-1 : CAWG_01005 || 1 0.09 0.06 0.64 -1.01 -0.10 -0.39 0.00 -0.41 0.56 -0.10 0.51 0.53 0.42 0.17
4536 || orf19.5001 || CUP2 || || Putative copper-binding transcription factor; required for normal resistance to copper; activates transcription of metallothionein genes; Hap43-repressed; Spider biofilm induced || 1 -0.08 0.17 -0.19 -0.69 0.18 -0.20 0.27 -0.28 0.27 0.23 -0.27 -0.10 0.69 0.50 0.20 -0.17
4537 || orf19.2430 || || || Ortholog of Candida albicans WO-1 : CAWG_00792 || 1 -0.36 0.37 0.36 -1.03 0.45 0.79 -0.34 0.13 0.15 1.01 -0.15 -0.05
4538 || orf19.3791 || FGR10 || || Putative asparaginase; lacks ortholog in S. cerevisiae; transposon mutation affects filamentous growth; Spider biofilm induced || 1 -0.50 0.85 -0.20 -0.95 0.43 0.33 -0.56 0.58 -0.01 -0.00 0.78 0.17 0.39 0.26 -0.12
4539 || orf19.2539 || || || Protein of unknown function; transcript detected on high-resolution tiling arrays || 1 0.44 0.29 0.35 -0.64 0.81 -0.01 0.15 0.31 -0.18 0.09 -0.03 -0.10 0.37 0.35 0.05 -0.03
4540 || orf19.69.2 || || || Dubious open reading frame || 1 0.76 0.29 0.32 -0.57 0.53 -0.96 0.37 -0.03 0.59 0.27 0.63 -0.10 0.43 0.37 0.61 -0.34
4541 || orf19.3582 || || || Ortholog(s) have protein-lysine N-methyltransferase activity, role in peptidyl-lysine dimethylation, vesicle-mediated transport and cytosol, nucleus localization || 1 0.03 0.28 -0.11 -0.10 0.40 0.04 -0.14 0.06 0.22 0.77 0.65 0.43 0.07 0.11 -0.06 -0.21
4542 || orf19.1298 || NUP84 || || Ortholog(s) have structural constituent of nuclear pore activity || 1 0.12 0.41 -0.23 -0.34 0.43 0.13 -0.14 -0.02 -0.08 0.13 0.52 0.49 0.09 0.25 -0.04 -0.15
4543 || orf19.3686 || || || Ortholog(s) have protein domain specific binding activity, role in mitochondrial proton-transporting ATP synthase complex assembly and mitochondrion localization || 1 0.08 0.40 -0.23 -0.32 0.21 -0.08 0.04 0.25 -0.24 0.47 0.57 0.41 -0.01 0.14 -0.17 0.21
4544 || orf19.7011 || || || Ortholog(s) have 90S preribosome, cytoplasm, mitotic spindle pole body, nucleolus localization || 1 0.42 0.43 -0.44 -0.16 0.69 0.46 0.07 0.54 -0.58 1.24 0.09 -0.63 -0.32 -0.17 -0.29 0.30
4545 || orf19.7062 || RPA135 || || Putative RNA polymerase I subunit A135; repressed by prostaglandins || 1 -0.08 0.05 -0.71 -0.41 0.53 0.20 -0.06 0.35 -0.52 0.51 0.24 -0.19 -0.33 0.14 -0.22 0.61
4546 || orf19.1833 || || || Ortholog(s) have pseudouridine synthase activity || 1 -0.14 0.09 -0.63 -0.80 0.25 -0.01 0.07 0.41 -0.28 0.93 0.49 0.07 0.15 0.39 -0.09 0.76
4547 || orf19.1578 || || || Ortholog of S. cereviaie Rrp5, an RNA binding protein involved in synthesis of 18S and 5.8S rRNAs; Hap43-induced gene || 1 0.24 0.23 -1.07 -0.89 0.55 -0.01 0.13 1.10 -0.63 1.25 0.80 -0.09 -0.71 0.70 -0.18 0.56
4548 || orf19.2795 || LHP1 || || Ortholog(s) have tRNA binding activity, role in regulation of ascospore formation, tRNA 3'-trailer cleavage, endonucleolytic and nucleolus, nucleoplasm localization || 1 0.11 0.22 -1.30 -0.89 0.35 0.16 0.57 1.03 -0.64 1.30 1.07 0.27 -0.08 0.78 -0.36 0.51
4549 || orf19.1833 || || || Ortholog(s) have pseudouridine synthase activity || 1 0.14 0.11 -1.18 -0.75 0.59 0.44 0.75 1.11 -0.37 1.00 1.21 0.29 -0.19 0.39 0.27 1.01
4550 || orf19.596.1 || NOP10 || || Small nucleolar ribonucleoprotein; flucytosine induced || 1 0.28 0.28 -1.08 -0.95 1.21 0.31 0.99 1.25 -0.39 0.73 1.15 0.06 -0.09 -0.14 -0.09 0.53
4551 || orf19.1565 || || || Protein of unknown function || 1 0.35 0.38 -0.75 -0.74 0.94 0.81 0.14 0.60 -0.09 0.85 0.68 -0.15 -0.15 0.23 0.22 0.53
4552 || orf19.512 || || || Ortholog of S. cerevisiae Kre33; essential; S. cerevisiae ortholog is essential and is required for biogenesis of the small ribosomal subunit || 1 0.02 0.18 -0.67 -0.48 0.77 0.74 0.32 0.63 -0.12 1.12 0.62 -0.17 -0.11 0.47 0.15 0.43
4553 || orf19.3553 || RPF2 || || Putative pre-rRNA processing protein; Hap43p-induced gene; mutation confers hypersensitivity to 5-fluorocytosine (5-FC), 5-fluorouracil (5-FU), and tubercidin (7-deazaadenosine) || 1 -0.12 -0.11 -0.82 -0.72 0.38 0.36 0.57 1.12 -0.36 1.17 0.57 -0.54 -0.01 0.59 -0.63 -0.05
4554 || orf19.3564 || RPC40 || || Putative RNA polymerase; protein level decreases in stationary phase cultures; Hap43p-induced gene || 1 0.07 0.23 -0.28 -0.38 0.35 0.24 0.42 0.63 -0.53 0.95 0.60 -0.38 0.08 0.27 -0.32 0.36
4555 || orf19.1578 || || || Ortholog of S. cereviaie Rrp5, an RNA binding protein involved in synthesis of 18S and 5.8S rRNAs; Hap43-induced gene || 1 0.19 0.71 -0.14 -0.39 0.66 0.25 0.31 0.53 -0.32 1.36 0.33 -0.27 -0.05 0.43 -0.72 0.31
4556 || orf19.443 || || || Ortholog(s) have DNA-directed RNA polymerase activity, RNA polymerase III activity and role in tRNA transcription from RNA polymerase III promoter, transcription initiation from RNA polymerase III promoter || 1 -0.14 0.14 0.08 0.01 0.18 0.40 -0.02 0.56 -0.11 0.56 0.37 0.03 -0.06 0.83 -0.21 -0.14
4557 || orf19.3553 || RPF2 || || Putative pre-rRNA processing protein; Hap43p-induced gene; mutation confers hypersensitivity to 5-fluorocytosine (5-FC), 5-fluorouracil (5-FU), and tubercidin (7-deazaadenosine) || 1 0.19 0.12 -0.05 -0.04 0.58 0.75 0.38 1.03 -0.48 1.43 0.70 0.04 -0.38 0.97 -0.26 0.36
4558 || orf19.6710 || UTP9 || || Small-subunit processome protein; Ssr1-induced; repressed by prostaglandins; physically interacts with TAP-tagged Nop1 || 1 -0.05 -0.04 -0.41 -0.28 0.58 1.06 0.06 0.39 -0.33 0.91 0.33 0.25 -0.14 0.50 0.05 0.36
4559 || orf19.3125 || || || Ortholog(s) have cytosol, nucleus localization || 1 -0.05 -0.19 -0.08 0.04 0.27 0.18 -0.08 0.11 -0.21 0.48 0.17 0.17 0.04 0.37 0.01
4560 || orf19.2541 || || || Ortholog(s) have 3'-5'-exodeoxyribonuclease activity, endonuclease activity, role in apoptotic DNA fragmentation, cellular response to oxidative stress and cytosol, nucleus localization || 1 -0.05 0.32 -0.59 -0.69 0.70 0.69 0.04 0.17 0.43 0.76 0.93 0.56 0.36 -0.04 -0.18 0.21
4561 || orf19.5050 || MTO1 || || Putative mitochondrial protein; rat catheter biofilm induced || 1 -0.18 -0.11 -0.39 -0.64 0.31 0.82 0.05 0.00 0.21 0.48 0.17 0.28 0.09 0.30 -0.08 0.10
4562 || orf19.2280 || ZCF10 || || Putative transcription factor with zinc cluster DNA-binding motif || 1 -0.05 -0.17 -0.31 -0.51 0.45 0.78 0.23 0.29 -0.02 -0.16 0.14 0.56 -0.21 0.44 0.46 -0.12
4563 || orf19.2280 || ZCF10 || || Putative transcription factor with zinc cluster DNA-binding motif || 1 -0.35 -0.36 -1.03 -0.65 0.38 0.60 0.28 -0.05 0.29 0.01 0.03 0.27 -0.14 0.36 0.41 -0.19
4564 || orf19.4160 || || || Ortholog(s) have serine-type endopeptidase activity, role in glycoprotein metabolic process, mitochondrial tRNA threonylcarbamoyladenosine modification and mitochondrion localization || 1 0.09 -0.20 -0.61 -0.72 0.41 0.96 0.21 0.05 0.36 1.05 -0.07 0.38 0.42 -0.49 0.47 -0.44
4565 || orf19.3798 || || || Ortholog(s) have tRNA (guanine-N7-)-methyltransferase activity, role in tRNA methylation and nucleolus, tRNA methyltransferase complex localization || 1 0.10 -0.17 -0.55 -0.59 0.53 0.44 0.25 0.38 -0.18 0.97 -0.03 0.39 0.50 -0.29 0.54 -0.26
4566 || orf19.1466 || REX2 || || Putative 3'-5' RNA exonuclease with a predicted role in 3'-end processing of U4 and U5 snRNAs, 5S and 5.8S rRNAs; rat catheter biofilm induced || 1 -0.13 -0.32 -0.49 -1.08 0.98 0.52 0.17 0.30 0.11 0.82 0.25 0.16 -0.19 -0.22 0.55 -0.10
4567 || orf19.1466 || REX2 || || Putative 3'-5' RNA exonuclease with a predicted role in 3'-end processing of U4 and U5 snRNAs, 5S and 5.8S rRNAs; rat catheter biofilm induced || 1 -0.21 -0.21 -0.59 -1.02 1.05 1.00 0.17 0.27 0.07 0.91 0.26 0.59 -0.35 0.23 0.62 -0.22
4568 || orf19.182 || || || Ortholog(s) have rRNA (guanine-N1-)-methyltransferase activity, role in rRNA modification and endoplasmic reticulum, mitochondrion localization || 1 -0.13 -0.16 -0.44 -0.41 0.61 0.54 -0.03 0.22 0.00 0.63 -0.06 0.19 -0.32 0.08 0.26 -0.16
4569 || orf19.702 || || || Ortholog(s) have DNA helicase activity, role in regulation of translational termination and polysome localization || 1 -0.16 0.02 -0.59 -0.25 0.49 0.73 0.03 0.21 -0.28 0.62 0.39 0.41 -0.11 0.16 0.24 -0.50
4570 || orf19.2631 || || || Subunit of Elongator complex; required for modification of wobble nucleosides in tRNA in S. cerevisiae; Hap43-induced gene || 1 0.16 0.09 -0.88 -0.79 0.88 0.73 -0.08 -0.23 -0.54 0.93 0.19 0.19 -0.08 0.39 0.74 -0.73
4571 || orf19.2631 || || || Subunit of Elongator complex; required for modification of wobble nucleosides in tRNA in S. cerevisiae; Hap43-induced gene || 1 0.29 0.15 -1.00 -0.71 0.87 0.69 -0.09 -0.19 -0.62 0.73 0.10 0.20 0.00 0.34 0.85 -0.44
4572 || orf19.5987 || || || Ortholog(s) have tRNA (guanine-N2-)-methyltransferase activity, role in tRNA methylation and cytosol, nucleus, tRNA (m2G10) methyltransferase complex localization || 1 -0.23 -0.37 -0.61 -0.51 1.01 0.84 0.22 0.01 -0.19 0.70 -0.00 -0.22 0.45 0.30 0.30 -0.06
4573 || orf19.1360 || || || Ortholog(s) have role in mitochondrial genome maintenance and mitochondrion localization || 1 -0.02 -0.37 -0.39 -0.59 0.32 0.87 0.42 -0.02 -0.07 0.31 -0.05 -0.23 0.32 0.27 0.38 -0.15
4574 || orf19.2043 || || || Ortholog of C. dubliniensis CD36 : Cd36_15750, C. parapsilosis CDC317 : CPAR2_213000, Debaryomyces hansenii CBS767 : DEHA2D18524g and Pichia stipitis Pignal : PICST_42355 || 1 -0.11 -0.01 -0.15 -0.54 0.64 0.35 0.43 0.24 -0.03 0.34 0.36 -0.11 0.40 0.20 0.62 -0.13
4575 || orf19.1769 || || || Ortholog(s) have G-protein beta/gamma-subunit complex binding, actin binding activity, role in positive regulation of transcription from RNA polymerase II promoter by pheromones, protein folding and cytoplasm localization || 1 -0.09 0.21 -0.61 -0.42 1.19 0.80 0.21 0.30 -0.26 -0.00 0.44 0.03 0.03 0.18 0.74 0.12
4576 || orf19.7215.3 || || || Ortholog(s) have chaperone binding, unfolded protein binding activity, role in protein refolding and mitochondrial matrix localization || 1 -0.03 0.04 -0.93 -1.18 2.05 1.46 0.92 0.82 0.31 0.05 0.89 0.48 0.02 -0.06 1.71 -0.27
4577 || orf19.6600 || || || Ortholog(s) have phosphatidic acid transporter activity and role in cardiolipin metabolic process, phospholipid transport, positive regulation of phosphatidylcholine biosynthetic process || 1 -0.40 -0.10 -0.78 -1.21 1.64 1.46 0.15 0.30 0.15 -0.14 0.06 0.07 0.02 -0.04 1.04 -0.19
4578 || orf19.7215.3 || || || Ortholog(s) have chaperone binding, unfolded protein binding activity, role in protein refolding and mitochondrial matrix localization || 1 -0.41 -0.43 -1.27 -1.52 1.54 1.10 0.59 0.49 -0.03 -0.31 0.53 -0.20 -0.17 -0.45 1.16 -0.64
4579 || orf19.91 || || || Protein of unknown function; flow model biofilm induced; Hap43-repressed || 1 0.08 -0.20 -0.83 -0.74 1.25 0.84 0.46 0.28 0.33 -0.19 0.06 -0.20 0.31 -0.50 0.86 -0.05
4580 || orf19.3062 || || || Ortholog(s) have role in chromatin remodeling and ASTRA complex, mitochondrion localization || 1 -0.11 -0.08 -0.24 -0.33 0.63 0.20 0.17 0.03 0.31 0.22 0.19 -0.02 0.07 -0.03 0.54 -0.13
4581 || orf19.336 || YAH1 || || Protein similar to oxidoreductases; induced in high iron; Hap43-repressed || 1 0.10 0.07 -0.79 -0.69 1.12 0.28 0.21 0.33 0.45 0.74 0.56 0.30 0.12 -0.37 0.47 0.03
4582 || orf19.6507 || || || Putative curved DNA-binding protein orthologous to S. pombe Cdb4; stationary phase enriched protein; rat catheter and Spider biofilm repressed || 1 0.15 0.15 -0.24 -0.27 1.13 0.32 0.30 0.52 -0.12 0.25 0.39 0.19 -0.03 -0.28 0.32 0.06
4583 || orf19.4721 || || || Ortholog(s) have RNA binding activity, role in cytoplasmic translation, mRNA processing and mitochondrion localization || 1 -0.19 -0.05 -0.72 -0.72 0.66 0.30 0.25 0.63 -0.11 0.24 0.19 -0.49 0.14 -0.12 0.30 -0.07
4584 || orf19.2500 || || || Has domain(s) with predicted transferase activity and role in biosynthetic process || 1 -0.29 -0.44 -0.93 -0.98 0.77 0.34 0.54 0.47 0.09 0.67 0.43 0.44 0.46 -0.05 0.23 0.24
4585 || orf19.4078 || || || Ortholog(s) have role in U1 snRNA 3'-end processing, U4 snRNA 3'-end processing and U5 snRNA 3'-end processing, more || 1 -0.49 -0.25 -1.16 -1.05 0.52 0.56 0.76 0.34 -0.18 0.69 0.54 0.41 0.69 0.18 0.64 -0.42
4586 || orf19.3798 || || || Ortholog(s) have tRNA (guanine-N7-)-methyltransferase activity, role in tRNA methylation and nucleolus, tRNA methyltransferase complex localization || 1 -0.50 -0.29 -0.61 -1.05 0.29 0.46 0.60 -0.07 -0.18 1.18 0.55 0.31 0.42 0.17 0.25 -0.43
4587 || orf19.4273 || || || Putative mitochondrial membrane protein; ortholog of S. cerevisiae Sls1; coordinates expression of mitochondrially-encoded genes; Hap43-induced || 1 -0.24 -0.08 -2.15 -1.93 0.94 0.14 1.01 0.55 -0.30 1.31 0.69 -0.43 1.25 -0.31 1.34 -1.29
4588 || orf19.6041 || RPO41 || || Putative mitochondrial RNA polymerase; repressed in core stress response; Spider biofilm induced || 1 -0.24 -0.28 -1.19 -1.10 0.10 -0.17 0.39 0.46 -0.23 0.68 0.30 -0.47 0.37 0.07 0.19 -0.64
4589 || orf19.3477 || || || Putative pseudouridine synthase; predicted role in snRNA pseudouridine synthesis, tRNA pseudouridine synthesis; Spider biofilm induced || 1 -0.08 -0.32 -0.91 -0.90 0.19 0.33 0.42 -0.14 -0.94 0.52 0.23 -0.57 0.47 0.48 0.09 0.09
4590 || orf19.7332 || ELF1 || || Putative mRNA export protein; Walker A and B (ATP/GTP binding) motifs; required for wild-type morphology, growth; expressed in hyphal, pseudohyphal, and yeast form; Hap43-induced; Spider and flow model biofilm induced || 1 -0.07 0.03 -0.51 -0.68 0.21 0.58 0.48 0.24 -0.62 0.84 0.44 -0.60 0.76 0.76 -0.22 -0.21
4591 || orf19.2594 || || || Ortholog(s) have RNA polymerase I activity, role in transcription of nuclear large rRNA transcript from RNA polymerase I promoter and DNA-directed RNA polymerase I complex, cytosol localization || 1 0.42 0.39 -0.90 -0.89 0.63 0.76 0.23 0.29 -0.71 1.15 0.47 -0.31 1.02 0.41 0.85 -0.52
4592 || orf19.2594 || || || Ortholog(s) have RNA polymerase I activity, role in transcription of nuclear large rRNA transcript from RNA polymerase I promoter and DNA-directed RNA polymerase I complex, cytosol localization || 1 0.36 0.35 -1.20 -0.94 0.59 0.66 0.19 0.32 -0.64 1.17 0.69 -0.25 0.85 0.61 0.97 -0.16
4593 || orf19.1633 || UTP4 || || Putative U3 snoRNA-associated protein; Hap43-induced; physically interacts with TAP-tagged Nop1; Spider biofilm induced || 1 0.11 0.13 -1.36 -0.89 0.55 0.63 0.19 0.54 -0.59 1.01 0.47 -0.64 0.38 0.48 0.03 -0.03
4594 || orf19.3477 || || || Putative pseudouridine synthase; predicted role in snRNA pseudouridine synthesis, tRNA pseudouridine synthesis; Spider biofilm induced || 1 -0.39 -0.11 -1.07 -0.82 0.28 0.33 0.55 0.03 -0.52 1.19 0.63 -0.23 0.84 0.94 0.37 0.42
4595 || orf19.2513 || || || Ortholog of C. dubliniensis CD36 : Cd36_81010, C. parapsilosis CDC317 : CPAR2_103060, Candida tenuis NRRL Y-1498 : CANTEDRAFT_127339 and Debaryomyces hansenii CBS767 : DEHA2G01936g || 1 -0.64 0.14 -0.66 -1.09 0.53 0.17 0.14 0.08 -0.38 0.74 0.35 -0.12 0.78 0.96 0.63 -0.29
4596 || orf19.5802 || || || Ortholog(s) have role in maturation of SSU-rRNA and cytoplasm, nucleus localization || 1 -0.18 -0.40 -0.62 -0.63 0.70 -0.18 0.30 0.31 -0.10 1.41 0.72 0.03 0.34 0.72 0.14 -0.87
4597 || orf19.423 || || || Ortholog(s) have enzyme activator activity, m7G(5')pppN diphosphatase activity, mRNA binding activity, role in deadenylation-dependent decapping of nuclear-transcribed mRNA and cytoplasmic mRNA processing body localization || 1 0.20 0.19 -1.19 -0.26 0.57 -0.20 0.76 0.60 0.22 0.61 0.89 0.09 -0.36 -0.02 0.71 -0.17
4598 || orf19.2433 || || || Ortholog of C. dubliniensis CD36 : Cd36_05790, C. parapsilosis CDC317 : CPAR2_103730, Pichia stipitis Pignal : PICST_28344, Candida tropicalis MYA-3404 : CTRG_04275 and Candida albicans WO-1 : CAWG_00795 || 1 0.28 0.10 -3.56 0.05 1.82 0.72 1.05 1.61 -0.20 0.58 1.66 0.42 0.68 0.42 2.26 -0.16
4599 || orf19.3429 || FGR47 || || Protein lacking an ortholog in S. cerevisiae; transposon mutation affects filamentous growth || 1 0.52 0.25 -0.88 -0.26 0.58 0.21 0.31 0.45 -0.13 0.29 0.51 0.11 0.79 0.56 0.58 0.12
4600 || orf19.5574 || || || Ortholog(s) have mitochondrial outer membrane localization || 1 0.02 -0.32 -1.36 -0.43 0.29 -0.05 0.19 0.53 0.02 0.33 0.10 0.39 0.24 0.31 0.44 0.24
4601 || orf19.2476 || || || Ortholog(s) have histone demethylase activity (H3-trimethyl-K4 specific) activity || 1 -0.28 -0.27 -0.41 -0.54 0.28 -0.13 0.71 0.34 0.34 0.06 0.26 0.19 -0.20 0.43 0.36 0.31
4602 || orf19.2699 || ABP1 || || Ortholog of S. cerevisiae Abp1; actin-binding protein of the cortical actin cytoskeleton; caspofungin induced; protein only detected in stationary phase yeast-form cultures; Spider biofilm repressed || 1 -0.25 -0.26 -0.38 -0.70 0.09 -0.17 0.63 0.53 0.34 -0.07 0.33 0.20 -0.43 0.07 0.27 -0.07
4603 || orf19.4252 || || || Ortholog(s) have protein serine/threonine kinase activity || 1 0.03 -0.35 -0.52 -0.72 -0.01 0.18 0.47 0.12 0.12 -0.00 0.56 0.36 -0.22 0.05 0.03 0.22
4604 || orf19.6171 || NUP159 || || FG-nucleoporin component of central core of the nuclear pore complex (NPC); contributes to nucleocytoplasmic transport; rat catheter biofilm repressed || 1 -0.19 -0.21 -0.56 -0.81 0.61 -0.06 0.23 0.52 -0.24 -0.10 0.47 -0.05 -0.15 -0.19 0.41 0.16
4605 || orf19.392 || || || Ortholog(s) have role in mitochondrial respiratory chain complex III assembly and integral to mitochondrial membrane localization || 1 -0.33 -0.49 -1.48 -1.62 0.65 0.21 0.57 0.85 0.05 -0.03 0.86 0.41 -0.56 -0.41 0.14 0.50
4606 || orf19.392 || || || Ortholog(s) have role in mitochondrial respiratory chain complex III assembly and integral to mitochondrial membrane localization || 1 -0.41 -0.41 -0.79 -1.18 0.44 0.37 0.43 0.57 0.47 0.01 0.74 0.08 -0.34 -0.14 -0.15 0.20
4607 || orf19.3396 || HCH1 || || Ortholog of S. cerevisiae Hch1, a regulator of heat shock protein Hsp90; regulated by Gcn4; induced in response to amino acid starvation (3-aminotriazole treatment); mutants are viable || 1 -0.31 -0.31 -1.30 -1.17 1.18 0.61 0.74 1.41 0.16 0.38 1.65 0.21 0.11 0.05 0.31 0.17
4608 || orf19.7665 || || || Ortholog(s) have role in mitochondrial respiratory chain complex IV assembly and mitochondrial inner membrane localization || 1 0.06 -0.20 -1.22 -1.27 0.98 0.36 0.52 0.94 0.20 0.38 1.02 0.24 0.21 -0.62 0.28 0.12
4609 || orf19.7665 || || || Ortholog(s) have role in mitochondrial respiratory chain complex IV assembly and mitochondrial inner membrane localization || 1 -0.17 -0.26 -0.93 -1.00 0.64 0.63 0.58 1.33 0.56 0.64 0.81 0.36 -0.03 -0.55 0.57 0.38
4610 || orf19.490 || NAT5 || || Subunit of the N-terminal acetyltransferase NatA; Spider biofilm repressed || 1 0.03 -0.03 -0.67 -0.81 0.63 0.50 0.34 0.56 0.42 0.31 0.77 0.61 -0.49 0.15 0.14 0.08
4611 || orf19.490 || NAT5 || || Subunit of the N-terminal acetyltransferase NatA; Spider biofilm repressed || 1 -0.04 0.53 -0.81 -0.59 0.73 0.32 0.40 0.50 0.27 0.15 0.86 0.45 -0.45 -0.25 0.17 0.15
4612 || orf19.3574 || MDJ2 || || Predicted component of the mitochondrial import motor; involved in protein import into mitochondrial matrix; early-stage flow model biofilm induced || 1 0.69 0.51 -0.74 -1.19 0.52 0.24 1.22 1.34 -0.04 -0.29 0.85 -0.16 -0.13 0.31 0.31 0.63
4613 || orf19.2472 || || || Ortholog of S. pombe replication termination factor Rtf2; Spider biofilm induced || 1 0.10 0.12 -0.52 -0.68 0.49 0.49 0.65 0.79 -0.12 0.03 0.78 -0.43 -0.28 0.28 0.62 -0.18
4614 || orf19.1505 || || || Ortholog(s) have cytoplasm localization || 1 0.16 0.57 -1.30 -0.86 0.94 -0.00 0.54 0.65 0.50 0.37 0.76 -0.28 0.67 -0.62 0.30 -0.21
4615 || orf19.954 || || || Putative DnaJ-like chaperone; Hap43-repressed gene || 1 -0.13 0.66 -0.74 -0.50 0.21 -0.47 0.78 0.69 0.57 0.55 0.16 -0.33 0.62 -0.02 0.46 -0.78
4616 || orf19.6692 || MNN26 || || Putative alpha-1,2-mannosyltransferase; mutant sensitive to calcofluor, SDS and growth at 42 deg; present in detergent-resistant membrane fraction (possible lipid raft component); predicted N-terminal acetylation and transmembrane helix || 1 0.06 -0.03 -0.52 -0.39 0.73 -0.33 0.53 0.77 0.05 0.66 0.48 0.06 0.39 -0.03 0.58 -0.83
4617 || orf19.5376 || || || Ortholog of S. cerevisiae Elm1; a serine/threonine protein kinase that regulates cellular morphogenesis, septin behavior, and cytokinesis in S. cerevisiae; possibly an essential gene, disruptants not obtained by UAU1 method || 1 0.00 0.26 -0.40 -0.42 0.46 -0.17 0.48 0.49 -0.08 0.24 -0.03 0.07 0.31 0.12 0.21 -0.05
4618 || orf19.6913 || GCN2 || || Translation initiation factor 2-alpha (eIF2alpha) kinase; has nonessential role in amino acid starvation response, in contrast to S. cerevisiae homolog; similar to S. cerevisiae Gcn2p || 1 -0.08 0.02 -0.24 -0.07 0.26 0.00 0.12 0.12 0.01 0.01 0.03 0.05 -0.11 0.09 0.06 -0.04
4619 || orf19.1450 || || || Ortholog of C. dubliniensis CD36 : Cd36_16320, Candida tropicalis MYA-3404 : CTRG_01238 and Candida albicans WO-1 : CAWG_03918 || 1 -0.38 -0.12 -1.57 -0.04 -0.39 -0.45 0.44 -0.06 0.84 -0.49 -0.68 -1.15
4620 || orf19.5574 || || || Ortholog(s) have mitochondrial outer membrane localization || 1 -0.39 -0.48 -1.18 -0.76 0.04 0.27 0.15 -0.30 -0.13 0.30 0.32 0.66 0.18 0.60 -0.06 -0.63
4621 || orf19.4814 || || || Ortholog of C. dubliniensis CD36 : Cd36_08960, C. parapsilosis CDC317 : CPAR2_301680, Candida tenuis NRRL Y-1498 : cten_CGOB_00021 and Debaryomyces hansenii CBS767 : DEHA2F11088g || 1 -0.05 -0.93 -1.86 -0.58 0.30 -0.57 -0.16 0.25 0.51 0.64 1.61 -0.21 1.75 0.13
4622 || orf19.2638 || || || Protein of unknown function; Spider biofilm induced || 1 0.31 -0.16 -1.27 -0.17 0.29 -0.10 -0.03 0.56 -0.47 0.34 -0.32 0.09 0.50 0.46 -0.07 -0.30
4623 || orf19.1266 || || || Protein of unknown function; transcript detected on high-resolution tiling arrays || 1 -0.46 -0.50 -0.80 -0.10 0.12 0.02 0.24 -0.11 -0.26 -0.60 -0.16 -0.22 -0.12 0.34 0.18 -0.16
4624 || orf19.3089 || || || Predicted mitochondrial intermembrane space protein; predicted role in phospholipid metabolism; rat catheter and Spider biofilm induced || 1 -1.94 -1.91 -1.18 -0.68 -0.30 0.22 0.16 -1.37 -1.47 -0.20 -0.53 -0.64 0.04 0.99 -0.08 -0.96
4625 || orf19.3330 || CRL1 || || Predicted GTPase of RHO family; CAAX motif geranylgeranylated; expression in S. cerevisiae causes dominant-negative inhibition of pheromone response || 1 -0.76 -0.97 -0.69 -0.76 -0.50 -0.08 0.67 -0.53 -0.57 -0.32 0.04 -0.18 0.18 0.90 -0.01 0.02
4626 || orf19.3330 || CRL1 || || Predicted GTPase of RHO family; CAAX motif geranylgeranylated; expression in S. cerevisiae causes dominant-negative inhibition of pheromone response || 1 -0.76 -0.72 -0.85 -0.71 -0.49 0.03 0.70 -0.58 -0.52 -0.37 -0.09 -0.10 0.19 0.32 0.15 0.33
4627 || orf19.4231 || PTH2 || || Putative cAMP-independent regulatory protein; constitutive expression independent of MTL or white-opaque status; Spider biofilm induced || 1 -0.84 -0.95 -1.75 -1.26 0.05 0.90 0.78 -0.96 -1.03 -0.90 0.16 0.67 0.50 0.57 0.13 0.20
4628 || orf19.4231 || PTH2 || || Putative cAMP-independent regulatory protein; constitutive expression independent of MTL or white-opaque status; Spider biofilm induced || 1 -1.23 -1.52 -0.95 -1.24 0.42 1.54 0.77 -0.93 -1.82 -1.24 0.09 0.54 0.74 0.60 0.02 0.46
4629 || orf19.4222 || SST2 || || Predicted regulator of G-protein signaling in mating pathway; null mutation causes alpha-factor hypersensitivity and mating defect (in opaque MTLa/MTLa background); transcript induced by alpha factor || 1 0.12 0.10 -0.40 -1.09 0.51 0.98 0.31 0.03 0.02 -0.55 0.10 -0.31 -0.10 1.04 0.09 0.63
4630 || orf19.6940 || || || Protein of unknown function || 1 0.05 -0.01 -0.82 -0.83 -0.17 0.71 0.37 0.22 -0.47 -0.27 -0.24 0.52 -0.02 1.13 0.48 0.19
4631 || orf19.605 || || || Ortholog of Candida albicans WO-1 : CAWG_02087 || 1 -0.08 -0.04 -1.02 -0.83 -0.15 0.68 0.25 -0.04 -0.96 -0.37 0.09 0.09 -0.33 0.27 0.16
4632 || orf19.3666 || || || Predicted debranching enzyme-associated ribonuclease; rat catheter biofilm induced || 1 -0.16 -0.13 -0.39 -0.71 0.02 0.06 -0.01 -0.33 -0.45 0.09 0.06 0.26 0.07 0.28 -0.33 0.21
4633 || orf19.4062 || TRY2 || || Transcription factor; regulator of yeast form adherence; required for yeast cell adherence to silicone substrate; Spider biofilm induced || 1 -0.49 -0.34 -0.45 -1.16 0.26 0.34 0.13 -0.36 -0.24 0.32 0.59 0.27 -0.03 0.20 -0.11 0.14
4634 || orf19.210 || || || Ortholog(s) have role in protein localization to bud neck and cellular bud neck, cytosol localization || 1 -0.60 -0.18 -0.57 -0.89 0.38 0.20 -0.13 -0.08 -0.05 -0.03 0.87 0.31 -0.22 0.55 -0.04 0.31
4635 || orf19.639 || || || S. cerevisiae ortholog YDR370C/DXO1 has decapping and 5′-3′ exoRNase activity; decreased transcription is observed upon fluphenazine treatment or in an azole-resistant strain that overexpresses CDR1 and CDR2 || 1 -0.37 -0.12 -1.43 -0.71 0.47 0.39 -0.27 -0.04 -0.09 0.46 0.10 0.54 -0.02 0.73 -0.29 0.47
4636 || orf19.2035 || || || Ortholog of C. parapsilosis CDC317 : CPAR2_212930, C. dubliniensis CD36 : Cd36_15830, Candida orthopsilosis Co 90-125 : CORT_0A12240 and Candida tropicalis MYA-3404 : CTRG_01155 || 1 -0.29 -0.23 -1.35 0.04 -0.28 -0.06 -0.58 0.63 -0.25 0.76 0.12 0.48 0.49 0.89
4637 || orf19.4629 || || || Ortholog(s) have ubiquitin-ubiquitin ligase activity, role in mitochondrion inheritance, protein monoubiquitination, protein polyubiquitination and plasma membrane, ubiquitin ligase complex localization || 1 -0.36 -0.02 -1.16 -0.86 0.39 0.67 0.12 -0.28 -0.03 0.14 -0.62 0.45 -0.25 0.55 0.58 0.62
4638 || orf19.6423 || || || Ortholog(s) have fructose-2,6-bisphosphate 2-phosphatase activity, role in glucose metabolic process and cytoplasm localization || 1 -0.19 -0.21 -1.20 -0.35 0.58 0.61 -0.43 -0.12 -0.06 0.09 0.27 0.29 -0.43 0.03 0.60 0.16
4639 || orf19.5050 || MTO1 || || Putative mitochondrial protein; rat catheter biofilm induced || 1 -0.30 -0.30 -0.91 -1.06 0.15 0.46 0.11 -0.35 -0.01 0.55 -0.47 0.10 -0.40 0.53 0.12 -0.40
4640 || orf19.1849 || || || Ortholog(s) have U3 snoRNA binding, rRNA binding activity, role in maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) and nucleolus, small-subunit processome localization || 1 -0.18 -0.46 -0.50 -0.93 0.40 0.60 -0.04 -0.46 -0.28 0.35 -0.06 -0.19 -0.14 0.56 -0.18 0.10
4641 || orf19.5412 || || || Ortholog of S. cerevisiae : ECM9, C. glabrata CBS138 : CAGL0L02255g, C. dubliniensis CD36 : Cd36_80470, C. parapsilosis CDC317 : CPAR2_503390 and Candida tenuis NRRL Y-1498 : CANTEDRAFT_133107 || 1 -0.34 -0.35 -0.35 -0.38 0.85 0.50 -0.11 -0.68 -0.02 0.24 -0.26 -0.07 -0.31 0.24 0.49 0.08
4642 || orf19.1360 || || || Ortholog(s) have role in mitochondrial genome maintenance and mitochondrion localization || 1 -0.58 -0.53 -0.25 -0.48 0.71 0.38 0.20 -0.18 -0.11 0.54 -0.50 -0.14 -0.14 0.43 0.39 -0.04
4643 || orf19.6594 || PLB3 || || GPI-anchored cell surface phospholipase B; possibly secreted; fungal-specific (no mammalian homolog); induced by Tbf1; fluconazole-induced; possible essential gene (UAU1 method); Spider and flow model biofilm induced || 1 -0.40 -0.28 -0.28 -0.38 0.88 0.65 0.12 -0.51 0.31 0.28 -0.72 -0.10 0.16 0.60 0.73 -0.84
4644 || orf19.4566 || || || Protein similar to S. cerevisiae Rot1p, which has roles in cytoskeletal dynamics and cell wall biosynthesis; predicted Kex2p substrate || 1 -0.36 -0.17 -0.01 -0.53 0.46 0.71 0.01 -0.43 0.31 0.30 -0.48 0.32 -0.09 0.60 0.34 -0.16
4645 || orf19.971 || SKN7 || || Putative homolog of S. cerevisiae Skn7p, which is predicted to be a response regulator protein in a phosphorelay signal transduction pathway; required for normal hydrogen peroxide resistance || 1 -0.26 -0.31 -0.19 -0.33 0.12 0.19 -0.11 -0.12 0.13 0.21 0.00 0.13 0.01 0.48 0.04 0.24
4646 || orf19.3638 || PGA46 || || Putative GPI-anchored protein; secreted; fluconazole-induced || 1 -0.50 -0.20 0.29 -0.02 0.20 0.29 0.14 -0.21 -0.44 0.09 -0.17 0.47 0.46 0.58 0.14 0.51
4647 || orf19.5849 || CWT1 || || Zn2Cys6 transcription factor involved in negative regulation of nitrosative stress response; mutant has cell wall defects; transcription increased at stationary phase; has predicted PAS domain; similar to S. cerevisiae Rds2p || 1 -0.51 -0.37 0.28 -0.22 -0.13 0.09 0.15 -0.28 -0.02 -0.37 0.51 0.52 0.60 0.64 0.25 0.73
4648 || orf19.4428 || || || Ortholog of C. dubliniensis CD36 : Cd36_06910, C. parapsilosis CDC317 : CPAR2_208560, Candida tenuis NRRL Y-1498 : CANTEDRAFT_95854 and Debaryomyces hansenii CBS767 : DEHA2F25982g || 1 -0.47 -0.33 0.12 -0.11 -0.28 -0.28 -0.05 0.11 -0.01 0.11 0.33 0.69 0.69 0.71 0.41 0.60
4649 || orf19.2037 || || || Ortholog of C. dubliniensis CD36 : Cd36_15810, C. parapsilosis CDC317 : CPAR2_212950, Candida tenuis NRRL Y-1498 : CANTEDRAFT_116162 and Debaryomyces hansenii CBS767 : DEHA2D18392g || 1 -0.44 -0.21 -0.16 -0.10 -0.15 0.17 -0.02 0.05 -0.11 -0.02 0.29 0.39 0.62 0.66 0.31 0.34
4650 || orf19.2963 || || || Has domain(s) with predicted NAD+ binding activity || 1 -0.78 -0.78 -0.11 -0.23 -0.32 -0.01 0.18 -0.02 0.24 0.04 -0.10 0.41 0.17 0.82 0.47 0.33
4651 || orf19.5725 || || || Ortholog(s) have guanyl-nucleotide exchange factor activity, role in autophagic vacuole fusion, protein targeting to vacuole, vesicle docking and Mon1-Ccz1 complex localization || 1 -0.40 -0.28 0.03 -0.35 0.16 0.00 0.14 -0.15 0.75 0.39 -0.07 0.52 0.46 0.60 0.45 0.82
4652 || orf19.894 || || || Ortholog(s) have guanyl-nucleotide exchange factor activity, role in retrograde transport, endosome to Golgi and Golgi membrane, Ric1p-Rgp1p complex, guanyl-nucleotide exchange factor complex localization || 1 -0.17 0.00 0.10 0.04 0.07 -0.02 -0.01 0.10 0.10 -0.17 0.23 0.26 0.20 0.16 0.17 0.42
4653 || orf19.1464 || BMT5 || || Putative beta-mannosyltransferase involved in beta-1,2-mannosylation of phospholipomannan; 9-member family includes Bmt1, Bmt2, Bmt3, and Bmtp with roles in mannosylation of cell wall phosphopeptidomannan; Spider biofilm induced || 1 -0.29 -0.26 0.26 0.32 0.03 -0.27 0.32 0.18 0.30 -0.79 0.40 0.49 0.26 0.62 0.19 0.56
4654 || orf19.1343 || MED16 || || Putative RNA polymerase II mediator complex subunit; induced by nitric oxide || 1 -0.29 -0.42 0.44 0.17 0.05 -0.15 0.19 0.17 0.33 0.05 0.18 0.55 -0.05 0.36 0.04 0.38
4655 || orf19.2963 || || || Has domain(s) with predicted NAD+ binding activity || 1 -0.38 -0.39 0.05 0.11 0.00 -0.14 0.17 0.01 0.08 0.15 0.03 0.07 0.13 0.07 0.27 0.18
4656 || orf19.6186 || || || Predicted protein of unknown function; overlaps orf19.6185 || 1 -0.50 -0.37 -0.03 0.08 0.10 0.09 0.31 0.08 0.18 0.08 0.09 0.21 0.50 -0.29 0.34 -0.09
4657 || orf19.5247 || || || Ortholog(s) have cytoplasm localization || 1 -0.37 -0.27 0.14 -0.12 0.53 0.25 0.09 0.14 0.25 -0.06 0.36 -0.04 0.53 -0.04 0.29 0.23
4658 || orf19.3422 || FMP27 || || Putative mitochondrial protein; mRNA binds She3 || 1 -1.15 -1.10 -0.62 -0.78 0.44 0.47 0.76 0.28 0.39 -0.80 0.54 0.44 1.79 0.10 0.68 0.70
4659 || orf19.6792 || RRD1 || || Putative peptidyl-prolyl cis/trans-isomerase; caspofungin induced || 1 -0.82 -0.90 -0.50 -0.18 0.46 0.15 -0.07 -0.12 -0.17 -0.23 -0.12 0.20 0.44 0.41 0.69 -0.16
4660 || orf19.6792 || RRD1 || || Putative peptidyl-prolyl cis/trans-isomerase; caspofungin induced || 1 -0.76 -0.74 -0.73 -0.45 0.60 0.21 0.02 0.17 0.08 -0.06 0.04 0.39 0.49 0.64 1.02 0.04
4661 || orf19.6792 || RRD1 || || Putative peptidyl-prolyl cis/trans-isomerase; caspofungin induced || 1 -0.59 -0.51 -0.44 -0.38 0.72 0.61 -0.02 -0.27 0.10 -0.41 -0.02 0.43 0.56 0.56 0.68 0.07
4662 || orf19.2749 || || || BTB/POZ domain protein; induced by Mnl1 under weak acid stress; flow model biofilm induced; Spider biofilm induced || 1 -0.68 -0.59 -0.71 0.01 0.59 -0.00 0.99 0.67 0.35 -0.01 0.44 0.67 0.82 0.45 1.04 0.46
4663 || orf19.2054 || FGR15 || || Putative transcription factor with zinc finger DNA-binding motif; lacks an ortholog in S. cerevisiae; transposon mutation affects filamentous growth; caspofungin induced; mutation causes marginal increase in caspofungin sensitivity || 1 -0.42 -0.90 -0.22 -0.43 0.26 0.02 0.03 0.19 0.20 0.60 0.82 0.58 -0.08 0.57 0.73 0.29
4664 || orf19.3557 || GPI19 || || Subunit of GPI-GlcNAc transferase; role in synthesis of N-acetylglucosaminyl phosphatidylinositol (GlcNAc-PI), the first intermediate in GPI anchor synthesis; complements S. cerevisiae gpi19 mutant; flow model biofilm induced || 1 -0.50 -0.81 -0.04 -0.12 0.63 0.21 0.18 0.28 0.36 -0.00 0.65 0.52 0.09 0.29 0.64 0.39
4665 || orf19.1750 || SLR1 || || Protein similar to mammalian SR-like RNA splicing factor; involved in filamentous growth and virulence; gene has intron; Spider biofilm repressed || 1 -0.53 -0.72 -0.56 -0.27 0.65 -0.03 0.23 0.18 0.27 -0.19 0.91 0.58 0.05 0.30 0.55 0.32
4666 || orf19.6798 || SSN6 || || Functional homolog of S. cerevisiae Cyc8/Ssn6; hyphal growth regulator; repressed during hyphal growth; Ssn6 and Tup1 regulate distinct sets of genes; overexpression or mutation causes avirulence in mouse IV infection; TPR motifs || 1 -0.49 -0.52 -0.43 -0.12 0.59 0.47 0.25 0.28 0.53 0.38 0.95 0.38 0.32 -0.25 0.88 0.41
4667 || orf19.5930 || || || Ortholog(s) have nucleocytoplasmic transporter activity, structural constituent of nuclear pore activity || 1 -0.23 -0.49 0.10 -0.05 0.41 0.67 0.26 0.38 0.49 0.03 0.16 0.18 0.22 0.12 0.75 0.57
4668 || orf19.4235 || PDE1 || || Low affinity cyclic nucleotide phosphodiesterase; mediates cAMP signaling in response to glucose or intracellular acidification; macrophage-repressed; Spider biofilm induced || 1 -0.73 -0.69 -0.60 -0.74 0.40 1.19 0.68 0.31 0.90 -0.20 0.21 0.67 0.35 0.56 0.93 0.73
4669 || orf19.7112 || FRP2 || || Putative ferric reductase; alkaline induced by Rim101; fluconazole-downregulated; upregulated in the presence of human neutrophils; possibly adherence-induced; regulated by Sef1, Sfu1, and Hap43 || 1 -0.47 -0.46 -0.32 -0.44 0.05 0.36 0.40 0.56 0.35 -0.34 0.56 0.48 -0.12 0.35 0.67 0.74
4670 || orf19.5247 || || || Ortholog(s) have cytoplasm localization || 1 -0.43 -0.50 -0.38 -0.14 0.31 0.65 0.09 0.05 0.09 -0.45 0.40 0.38 -0.13 0.09 0.55 0.22
4671 || orf19.6186 || || || Predicted protein of unknown function; overlaps orf19.6185 || 1 -0.35 -0.40 -0.08 0.23 0.08 0.26 0.05 0.28 0.01 0.10 0.11 0.31 0.00 0.01 0.65 0.12
4672 || orf19.6792 || RRD1 || || Putative peptidyl-prolyl cis/trans-isomerase; caspofungin induced || 1 -0.67 -0.75 -0.14 0.40 0.63 0.31 -0.06 0.31 -0.03 -0.29 0.11 0.50 0.61 0.05 1.03 0.05
4673 || orf19.7295 || || || Ortholog(s) have protein phosphatase 1 binding activity, role in actin filament organization, cortical actin cytoskeleton organization, endocytosis, protein secretion and actin cortical patch, nucleus localization || 1 -0.48 -0.25 0.02 0.01 0.45 0.23 -0.12 0.01 -0.22 -0.06 0.52 0.30 0.33 -0.02 0.94 0.46
4674 || orf19.4148 || || || Ortholog of C. dubliniensis CD36 : Cd36_50820, C. parapsilosis CDC317 : CPAR2_501670, Candida tenuis NRRL Y-1498 : CANTEDRAFT_115294 and Debaryomyces hansenii CBS767 : DEHA2E13464g || 1 -0.26 -0.36 -0.35 -0.20 0.07 0.19 -0.10 0.42 -0.17 -0.32 0.75 0.66 0.00 0.36 1.09 0.22
4675 || orf19.3914 || || || Has domain(s) with predicted translation initiation factor activity, role in translational initiation and cytoplasm localization || 1 -0.42 -0.34 -0.02 -0.94 0.35 0.27 0.14 -0.16 -0.10 0.01 0.32 0.67 0.27 0.20 0.44 -0.14
4676 || orf19.3945 || || || Predicted COP9 signalosome complex subunit 12; flow model biofilm induced || 1 -0.50 -0.46 -0.16 -0.60 0.20 0.35 0.14 -0.26 0.21 0.25 0.15 0.37 0.16 0.27 0.38 0.00
4677 || orf19.6797 || || || Ortholog of C. dubliniensis CD36 : Cd36_86960, C. parapsilosis CDC317 : CPAR2_808800, Candida tenuis NRRL Y-1498 : CANTEDRAFT_113621 and Debaryomyces hansenii CBS767 : DEHA2F02486g || 1 -0.27 -0.20 0.01 -0.24 0.08 0.09 -0.09 0.23 0.12 -0.02 0.05 0.24 0.08 0.04 0.06 0.02
4678 || orf19.6482 || || || Protein of unknown function; induced by nitric oxide independent of Yhb1p; regulated by Sef1, Sfu1, and Hap43; rat catheter biofilm induced || 1 -0.84 -0.51 -0.62 -1.85 0.22 -0.96 -0.16 -0.13 0.20 0.97 1.29 0.85 0.89 1.44 1.62 0.39
4679 || orf19.6912 || || || Putative ethanolamine kinase || 1 -0.12 -0.09 0.10 -0.43 0.34 0.11 0.04 0.27 0.34 0.26 0.49 0.49 0.50 0.46 0.39 -0.02
4680 || orf19.5871 || SNF5 || || SWI/SNF chromatin remodeling complex subunit involved in transcriptional regulation; mutants have defects in silicone adherence, biofilm formation, hyphal morphogenesis, cell wall defects; increased cell aggregation during yeast form growth || 1 0.08 -0.06 0.02 -0.04 0.10 -0.03 -0.09 0.33 -0.09 0.15 0.36 0.25 0.35 0.52 0.55 0.03
4681 || orf19.1592 || || || Protein of unknown function; Spider biofilm induced || 1 -0.24 -0.63 -0.77 -0.82 0.11 0.21 0.73 0.58 0.94 -0.09 0.38 0.91 0.54 -0.07 0.06 0.60
4682 || orf19.268 || || || Ortholog(s) have role in transcription-coupled nucleotide-excision repair and Ddb1-Ckn1 complex, cytosol localization || 1 -0.39 -0.12 -0.01 -0.34 0.03 0.03 0.08 0.02 0.50 -0.35 0.37 0.78 -0.08 0.06 0.26 0.66
4683 || orf19.2772 || HOS3 || || Histone deacetylase; similar to S. cerevisiae Hos3p; greater expression and longer mRNA in white cells, compared to opaque cells; has conserved deacetylation motif || 1 -0.24 -0.39 -0.35 -0.81 0.07 0.01 0.20 -0.29 0.57 -0.22 0.96 1.15 -0.73 -0.05 0.38 1.20
4684 || orf19.2430 || || || Ortholog of Candida albicans WO-1 : CAWG_00792 || 1 -0.32 -0.82 -1.36 -0.00 -0.08 -0.69 1.14 0.22 0.70 1.88 -1.24 0.74
4685 || orf19.6199 || || || Ortholog(s) have ATP-dependent 5'-3' DNA helicase activity and DNA helicase A complex, alpha DNA polymerase:primase complex, cytosol localization || 1 -0.09 -0.11 -0.28 -0.52 0.25 0.21 0.41 -0.02 0.56 0.05 0.19 0.54 -0.14 0.29 0.30 0.37
4686 || orf19.4768 || || || Protein of unknown function; Spider biofilm induced || 1 0.07 -0.02 -0.30 -0.54 0.41 0.04 0.10 0.02 0.30 0.09 -0.02 0.32 -0.10 0.32 0.27 0.54
4687 || orf19.4446 || || || Protein similar to ammomium permeases that is probably inactive, as a mep2 mep3 double homozygous null mutation abolishes cellular ammomium permease activity; fungal-specific (no human or murine homolog) || 1 -0.00 -0.28 -0.43 -0.42 0.09 0.04 -0.08 -0.06 0.48 0.25 0.31 0.32 0.14 -0.17 0.60 0.40
4688 || orf19.7463 || || || Ortholog(s) have role in ascospore wall assembly and ascospore wall, nuclear envelope localization || 1 -0.21 -0.55 -1.03 -0.88 0.21 0.06 -0.02 0.10 0.51 0.50 -0.33 -0.08 -0.09 -0.08 0.65 0.36
4689 || orf19.2057 || || || Ortholog(s) have ATP binding, ATPase activity, metallopeptidase activity, role in protein complex assembly, proteolysis, signal peptide processing and m-AAA complex, mitochondrial inner boundary membrane localization || 1 -0.16 -0.16 -0.64 -0.87 0.39 0.56 0.51 0.33 0.97 0.33 -0.24 0.01 -0.13 -0.11 0.56 0.26
4690 || orf19.2463 || PRN2 || || Protein similar to pirin; Hap43p-repressed gene || 1 -0.05 -0.07 -0.37 -0.08 0.03 0.60 0.20 0.15 0.14 0.34 -0.26 0.23 -0.31 0.02 0.45 0.27
4691 || orf19.5566 || || || Ortholog(s) have role in protein lipoylation and mitochondrion localization || 1 -0.41 -0.24 -0.26 -0.21 0.51 0.89 0.37 0.50 -0.23 0.46 -0.26 0.36 -0.25 0.10 0.48 0.39
4692 || orf19.1162.1 || || || Ortholog(s) have Golgi apparatus localization || 1 0.09 -0.21 0.12 -0.69 0.76 0.82 0.48 0.30 0.40 -0.00 0.06 -0.20 -0.06 0.47 0.54
4693 || orf19.1310 || || || Ortholog(s) have role in nucleotide-excision repair and nucleus localization || 1 -0.32 -0.20 0.07 -0.34 0.97 0.68 0.22 0.24 0.50 0.05 0.12 0.29 0.03 0.14 0.18 0.37
4694 || orf19.2818 || || || Ortholog(s) have RNA-dependent ATPase activity, second spliceosomal transesterification activity, role in generation of catalytic spliceosome for second transesterification step and U2-type catalytic step 2 spliceosome localization || 1 -0.58 -0.29 -0.21 -0.44 0.71 0.37 0.27 -0.11 0.00 0.17 -0.05 0.50 -0.24 -0.04 0.45 0.43
4695 || orf19.7245 || || || Ortholog(s) have tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity, role in mitochondrial tRNA thio-modification and mitochondrion localization || 1 -0.40 -0.49 -0.21 -0.33 0.61 0.40 0.41 -0.21 0.14 -0.06 -0.15 0.25 -0.06 0.05 0.20 0.11
4696 || orf19.2174 || RAD57 || || Putative DNA recombination and repair protein; induced by interaction with macrophage; transcript is regulated by Nrg1, Mig1, and Tup1; essential protein; S. cerevisiae ortholog is essential || 1 -0.33 -0.16 -0.74 -0.31 0.72 0.51 0.29 0.07 0.10 0.11 0.60 0.05 -0.16 0.09 0.13 0.83
4697 || orf19.2028 || MXR1 || || Putative methionine sulfoxide reductase; Plc1-regulated; induced by human neutrophils, flucytosine; macrophage regulated (gene induced, protein decreased); possibly adherence-induced; Spider biofilm induced || 1 -0.29 -0.31 -0.34 -0.28 0.34 0.30 0.67 0.19 0.38 -0.32 0.60 -0.26 -0.25 0.05 0.53 0.97
4698 || orf19.2028 || MXR1 || || Putative methionine sulfoxide reductase; Plc1-regulated; induced by human neutrophils, flucytosine; macrophage regulated (gene induced, protein decreased); possibly adherence-induced; Spider biofilm induced || 1 -0.19 -0.32 -0.72 -0.46 0.27 0.21 0.73 0.16 0.27 -0.45 0.53 -0.20 -0.38 -0.11 0.57 0.64
4699 || orf19.7260 || || || Protein with a predicted NADP-dependent oxidoreductase or aldo-keto reductase domain; Hap43-repressed; Spider biofilm repressed || 1 -0.23 -0.15 -0.18 0.02 0.12 0.17 0.45 0.20 0.68 0.13 0.19 -0.04 -0.31 0.15 0.09 0.45
4700 || orf19.5606 || || || Ortholog of Candida albicans WO-1 : CAWG_05051 || 1 -0.48 -0.43 -1.62 0.58 0.63 -0.14 -0.09 -0.02 -0.19 0.83 0.80 0.35 0.97 0.77 0.69
4701 || orf19.4636 || || || Predicted protein of unknown function; overlaps orf19.4636 || 1 0.20 -0.11 -0.24 0.52 0.79 -0.82 -0.13 0.40 0.10 0.60 0.39 -0.17 0.47 0.12 -0.04 0.88
4702 || orf19.4685 || || || Dubious open reading frame || 1 0.43 -0.14 -0.28 0.34 0.20 0.04 0.35 0.45 0.34 0.75 0.18 -0.70 0.07 0.37 0.53
4703 || orf19.7267 || SAM35 || || Predicted component of the sorting and assembly machinery (SAM complex) of the mitochondrial outer membrane, involved in protein import into mitochondria || 1 -0.01 -0.01 -0.21 -0.08 0.16 -0.17 0.05 0.18 0.17 0.27 -0.08 -0.06 -0.09 -0.11 0.28 0.29
4704 || orf19.1844 || || || Protein similar to ferric reductase Fre10p || 1 0.24 -0.77 -0.46 0.50 0.42 -0.03 0.67 1.04 0.20 0.66 -0.04 0.09 -0.08 0.90 0.53 -0.19
4705 || orf19.1958 || || || Dubious open reading frame || 1 0.20 0.05 -0.70 0.34 0.09 0.10 0.02 0.40 0.27 0.23 0.01 0.09 1.03 0.55 0.14
4706 || orf19.10711 || PIKALPHA || || Putative phosphatidylinositol kinase; non-sex gene located within the MTLalpha mating-type-like locus || 1 0.09 -0.23 -0.84 0.16 0.28 0.05 0.44 0.69 -0.09 0.13 0.01 0.70 -0.30
4707 || orf19.3736 || KAR4 || || Transcription factor; required for gene regulation in response to pheromones; ortholog of S. cerevisiae Kar4; role in karyogamy; opaque-specific, a-specific; induced by alpha factor || 1 -0.01 -0.31 -0.33 0.12 0.19 0.19 -0.16 0.56 0.10 -0.16 -0.10 -0.18 -0.15 -0.05 0.83 -0.09
4708 || orf19.7280 || || || Ortholog of Candida albicans WO-1 : CAWG_02163 || 1 0.28 0.93 -0.73 0.72 1.43 0.68 0.04 -0.12 0.66 0.21 -0.12 -0.21 0.73 -0.10
4709 || orf19.3589 || SPO11 || || DNA endonuclease; required for genetic recombination between homologous chromosomes during the parasexual cycle; produced in mitotically dividing cells; similar to S. cerevisiae Spo11 which functions in recombination during meiosis || 1 0.48 0.46 -0.04 0.58 0.69 0.22 -0.58 -0.22 0.06 -0.12 -0.02 0.17 0.54 0.17 -0.54
4710 || orf19.2481 || || || Protein of unknown function; Spider biofilm induced || 1 -0.03 0.84 0.25 0.78 0.81 -0.07 0.02 -0.20 -0.30 -0.76 -0.10 0.40
4711 || orf19.5256 || || || Protein of unknown function; Hap43-repressed gene; induced by alpha pheromone in SpiderM medium || 1 0.50 0.44 0.37 0.56 0.80 -0.19 0.22 0.17 0.76 -0.09 -0.86 -0.74 -0.08 0.87 0.33 -0.70
4712 || orf19.5029 || MODF || || Ortholog(s) have mitochondrion localization || 1 0.51 0.50 -0.04 0.31 0.54 -0.21 0.56 0.47 0.26 0.04 -0.47 -0.21 0.08 0.23 0.71 -0.16
4713 || orf19.3271 || || || Ortholog of Candida albicans WO-1 : CAWG_01442 || 1 0.49 0.28 0.18 0.44 -0.22 0.31 -0.10 0.69 -0.06 -0.17 -0.53 0.10 -0.07 0.98 0.55 -0.06
4714 || orf19.849 || || || Ortholog(s) have role in protein N-linked glycosylation, protein O-linked glycosylation, response to stress || 1 0.04 0.65 -0.62 0.72 0.20 0.13 0.69 0.03 -1.03 0.02 0.38 -0.27 0.84 0.65 -0.83
4715 || orf19.1577 || || || Has domain(s) with predicted sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity, zinc ion binding activity and role in regulation of transcription, DNA-dependent || 1 0.69 0.22 -0.30 0.22 0.27 0.59 0.18 0.28 -0.56 -0.27 -0.30 0.29 -0.28 0.26 -0.82
4716 || orf19.604 || || || Ortholog(s) have cytosol localization || 1 -0.14 -0.13 -0.50 0.90 0.55 0.48 0.52 0.22 -1.19 0.23 -0.11 0.02 0.05 0.99 0.76 0.06
4717 || orf19.605 || || || Ortholog of Candida albicans WO-1 : CAWG_02087 || 1 -0.31 -0.33 -0.06 0.05 0.72 0.74 0.17 0.16 -0.41 0.59 0.30 -0.35 0.83 0.63 -0.42
4718 || orf19.3693 || PGA5 || || Putative GPI-anchored beta-1,3-glucanosyltransferase with similarity to the A. fumigatus GEL family; fungal-specific (no human or murine homolog) || 1 -0.60 -0.51 -0.19 -0.06 -0.07 0.37 0.10 0.26 -0.80 0.01 -0.06 -0.02 -0.65 1.14 0.48
4719 || orf19.5100 || MLT1 || || Vacuolar membrane transporter; MRP subfamily of ABC family; may transport organic anions conjugated to glutathione, glucuronate, or sulfate; needed for virulence in mouse peritonitis; Spider biofilm induced; flow model biofilm repressed || 1 -0.23 -0.21 -0.21 0.13 0.32 0.06 -0.10 0.31 -0.50 0.20 0.30 0.03 -0.82 0.23 0.26 0.22
4720 || orf19.1421 || || || Ortholog(s) have ureidoglycolate hydrolase activity and cytosol, nucleus localization || 1 -0.23 -0.45 0.02 0.29 0.16 0.77 -0.41 0.03 -0.46 0.68 0.22 0.17 -0.86 0.25 0.13
4721 || orf19.4808 || NUP188 || || Putative nuclear pore complex subunit; transcript regulated by Nrg1 and Mig1 || 1 -0.04 -0.15 0.14 -0.02 -0.06 0.17 -0.41 -0.10 -0.19 0.19 0.26 0.46 -0.12 0.29 -0.02 0.35
4722 || orf19.4196 || || || Dubious open reading frame || 1 -0.45 -0.54 0.49 0.74 -0.72 0.97 -0.63 0.62 -0.76 0.38 0.42 0.30 0.63 0.89 1.08
4723 || orf19.3887 || || || Ortholog(s) have cytoplasm, nucleus localization || 1 0.16 0.09 0.15 -0.07 -0.05 0.70 -0.14 -0.20 -0.59 0.77 -0.04 0.57 0.26 0.37 -0.15 0.08
4724 || orf19.3320 || || || Dubious open reading frame || 1 -0.47 -0.36 -0.19 -0.19 -0.36 1.69 -0.28 0.08 -0.05 0.40 -0.04 0.41 -0.03 0.53 0.03 0.16
4725 || orf19.420 || || || Protein of unknown function || 1 0.08 -0.31 -0.09 1.79 -0.56 -0.23 0.48 -0.06 0.16 0.66 0.15 0.57 0.07 0.63
4726 || orf19.7055 || || || Dubious open reading frame || 1 0.42 -0.28 -0.30 0.52 0.17 2.52 0.06 0.07 -0.81 0.64 0.37 0.90 -0.12 0.11 0.43 0.97
4727 || orf19.3884 || FGR50 || || Protein lacking an ortholog in S. cerevisiae; transposon mutation affects filamentous growth; Spider biofilm repressed || 1 0.02 -0.17 0.05 -0.00 -0.23 1.02 0.04 0.21 -0.25 0.06 0.55 0.42 0.03 0.35 -0.14 0.31
4728 || orf19.3884 || FGR50 || || Protein lacking an ortholog in S. cerevisiae; transposon mutation affects filamentous growth; Spider biofilm repressed || 1 -0.15 -0.08 0.19 0.20 -0.12 1.17 0.08 0.44 -0.16 0.16 0.71 1.02 0.02 0.37 0.14 1.05
4729 || orf19.2469 || RAD10 || || Ortholog of S. cerevisiae Rad10, an endonuclease involved in nucleotide excision repair; mutant is extremely sensitive to UV irradiation; transcript repressed in alkaline conditions || 1 -0.44 0.15 0.08 0.09 0.16 0.66 -0.24 0.08 0.59 0.20 0.33 0.54 0.08 0.22 0.18 0.42
4730 || orf19.2980 || || || Ortholog(s) have ATP-dependent RNA helicase activity and role in generation of catalytic spliceosome for first transesterification step, spliceosomal complex disassembly || 1 -0.03 -0.10 0.10 -0.12 0.12 0.45 -0.11 0.35 0.62 0.29 -0.14 0.25 0.17 0.42 0.22 0.15
4731 || orf19.4167 || || || Protein of unknown function; Spider biofilm induced || 1 -0.14 0.22 0.33 0.28 0.46 1.70 -0.40 -0.06 1.00 1.34 -0.00 0.59 0.15 -0.01 0.88
4732 || orf19.2998 || TSR2 || || Protein with a predicted role in pre-rRNA processing; repressed by prostaglandins || 1 -0.23 0.01 0.27 0.26 0.17 1.14 -0.21 0.09 0.19 1.71 0.16 0.15 0.23 1.28 -0.45 0.14
4733 || orf19.73 || || || Putative metalloprotease; associates with ribosomes and is involved in ribosome biogenesis; Spider biofilm induced || 1 -0.23 -0.15 0.43 -0.03 0.41 0.48 -0.06 -0.03 0.12 0.57 -0.04 0.14 0.34 0.65 0.30 -0.16
4734 || orf19.5390 || || || Ortholog of Candida albicans WO-1 : CAWG_02403 || 1 -0.27 -0.27 0.57 0.10 0.15 0.26 -0.09 -0.01 -0.29 -0.05 0.22 0.17 0.20 0.26 -0.07 0.28
4735 || orf19.5389 || FKH2 || || Forkhead transcription factor; morphogenesis regulator; required for wild-type hyphal transcription, cell separation, and for virulence in cell culture; mutant lacks true hyphae, is constitutively pseudohyphal; upregulated in RHE model || 1 -0.18 -0.10 0.29 -0.01 0.27 0.28 -0.04 0.15 -0.15 -0.26 0.41 0.13 0.15 0.34 0.20 0.41
4736 || orf19.6482 || || || Protein of unknown function; induced by nitric oxide independent of Yhb1p; regulated by Sef1, Sfu1, and Hap43; rat catheter biofilm induced || 1 -0.40 0.34 0.01 1.08 -0.16 -0.36 -1.65 0.51 0.75 -0.12 -0.01 1.50 1.40
4737 || orf19.6491 || || || Ortholog of Candida albicans WO-1 : CAWG_05572 || 1 -0.14 -0.56 0.73 -0.79 0.17 1.31 -0.60 -0.73 0.05 0.03 -0.49 -0.47 1.09 1.51
4738 || orf19.942 || KRE62 || || Putative subunit of glucan synthase; macrophage-induced gene; Bcr1-regulated in a/a RPMI biofilms || 1 -0.45 -0.24 0.68 0.10 -0.15 0.33 -0.36 -0.14 -0.24 0.05 -0.46 -0.30 -0.05 1.08 0.44 0.82
4739 || orf19.6687 || || || Protein of unknown function; rat catheter biofilm repressed || 1 -0.70 0.06 1.41 0.44 0.73 -0.38 -0.55 -1.22 0.86 -0.31 -0.15 1.71 0.23
4740 || orf19.6807 || || || Predicted ORF in retrotransposon Tca17 with similarity to parts of the Gag-Pol region of retrotransposons; clade-associated gene expression || 1 0.41 0.67 1.68 0.55 1.62 -0.07 -0.23 -1.04 0.24 0.01 0.23 0.29 1.35 0.85 0.71
4741 || orf19.4741 || || || Protein of unknown function; C. albicans- and C. dubliniensis specific gene; rat catheter biofilm repressed || 1 0.06 0.33 1.11 0.22 0.68 1.90 0.55 0.11 -0.81 0.04 0.90 -0.33 0.25 0.41 0.35
4742 || orf19.6369 || RIO2 || || Putative serine kinase with a predicted role in the processing of the 20S pre-rRNA into mature 18S rRNA; null mutants are hypersensitive to caspofungin || 1 0.05 0.03 0.38 -0.05 0.07 0.61 0.11 0.01 -0.08 0.34 -0.05 -0.40 0.25 0.52 -0.01 0.10
4743 || orf19.741 || || || Dubious open reading frame || 1 -0.33 0.46 0.40 -0.46 0.62 1.13 -0.81 -0.36 0.19 -0.10 0.15 -0.03 0.05 0.76 0.47 0.54
4744 || orf19.5606 || || || Ortholog of Candida albicans WO-1 : CAWG_05051 || 1 -0.52 0.79 0.23 -0.88 -0.73 1.36 0.68 0.32 0.67 0.33 1.29 0.89 1.17
4745 || orf19.948 || || || Ortholog of Candida albicans WO-1 : CAWG_04435 || 1 -0.13 0.13 0.48 -0.36 -0.27 1.36 0.34 0.12 0.34 0.45 0.42 0.24 -0.94 1.09 0.73
4746 || orf19.6949 || || || Ortholog of Candida albicans WO-1 : CAWG_02687 || 1 0.14 0.07 0.05 -0.39 -0.10 0.50 -0.16 0.08 -0.25 0.15 0.60 0.45 -0.88 0.71 0.53 -0.07
4747 || orf19.6164 || || || Ortholog of Candida albicans WO-1 : CAWG_02424 || 1 -0.51 0.13 0.45 -0.64 0.17 0.02 -0.05 -0.28 0.12 0.50 -0.75 -0.05 0.47
4748 || orf19.212 || VPS28 || || ESCRT I protein sorting complex subunit; involved in Rim8 processing and proteolytic activation of Rim101, which regulates pH response; role in echinocandin, azole sensitivity || 1 0.22 0.12 0.41 0.16 0.34 0.18 0.21 0.19 0.16 0.19 0.49 0.05 -0.35 0.50 0.07 0.75
4749 || orf19.212 || VPS28 || || ESCRT I protein sorting complex subunit; involved in Rim8 processing and proteolytic activation of Rim101, which regulates pH response; role in echinocandin, azole sensitivity || 1 0.11 -0.11 0.34 0.29 0.65 1.11 0.34 0.24 0.20 0.10 0.98 0.27 -0.40 0.60 0.16 0.78
4750 || orf19.4779 || || || Putative transporter; slightly similar to the Sit1p siderophore transporter; Gcn4p-regulated; fungal-specific; induced by Mnl1p under weak acid stress || 1 0.28 0.40 0.26 0.45 0.62 0.90 -0.06 0.34 0.14 0.21 1.07 -0.33 -0.48 0.27 -0.06 0.53
4751 || orf19.4093 || PES1 || || Pescadillo homolog required for yeast cell growth, lateral yeast growth on filamentous cells and virulence in mice; hyphal cells grow normally in mutant; mutation confers hypersensitivity to 5-fluorocytosine, 5-fluorouracil, tubercidin || 1 -0.16 -0.19 0.44 0.48 0.04 0.44 0.17 0.31 -0.07 0.94 0.11 -0.10 -0.04 0.27 -0.18 0.50
4752 || orf19.7062 || RPA135 || || Putative RNA polymerase I subunit A135; repressed by prostaglandins || 1 0.10 0.09 0.71 0.46 0.51 0.36 0.28 0.05 -0.16 0.57 0.01 -0.10 -0.09 0.32 -0.04 0.75
4753 || orf19.855 || || || Ortholog of C. dubliniensis CD36 : Cd36_18340, Candida tenuis NRRL Y-1498 : CANTEDRAFT_124631, Debaryomyces hansenii CBS767 : DEHA2D04356g and Pichia stipitis Pignal : PICST_34839 || 1 0.15 -0.28 0.79 0.71 0.23 0.19 -0.18 0.35 0.10 0.48 -0.13 -0.38 -0.27 0.09 -0.01 0.66
4754 || orf19.6908 || || || Dihydrofolate synthetase involved in folic acid biosynthesis || 1 0.23 0.01 0.05 -0.22 0.09 0.23 -0.05 0.13 -0.14 -0.05 -0.02 -0.04 -0.41 0.25 0.02 0.46
4755 || orf19.3735 || || || Protein of unknown function; induced by alpha pheromone in SpiderM medium || 1 0.35 0.02 -0.78 0.31 -0.27 0.48 0.07 0.03 -0.59 0.48 0.16 0.44
4756 || orf19.4019 || || || Ortholog(s) have protein phosphatase regulator activity, role in negative regulation of DNA damage checkpoint, protein dephosphorylation and cytoplasm, nucleus localization || 1 0.15 0.18 -0.15 -0.26 0.15 -0.08 -0.16 0.28 0.26 0.04 -0.04 0.01 -0.36 0.28 0.53 0.31
4757 || orf19.227 || COX7 || || Putative cytochrome c oxidase; flucytosine induced; repressed by nitric oxide || 1 0.39 0.06 0.51 -0.52 0.03 0.22 -0.17 0.16 0.52 0.82 0.21 0.20 -0.38 1.06 -0.11 -0.10
4758 || orf19.7070 || || || Ortholog of Candida guilliermondii ATCC 6260 : PGUG_03499, Candida lusitaniae ATCC 42720 : CLUG_00410 and Candida albicans WO-1 : CAWG_05407 || 1 0.03 0.13 0.01 -2.13 0.78 0.64 -0.33 0.33 -0.21 -0.14 0.55 0.25
4759 || orf19.5277 || || || Ortholog(s) have role in nuclear-transcribed mRNA catabolic process, 3'-5' exonucleolytic nonsense-mediated decay, protein ubiquitination and cytoplasm, nucleolus, polysome localization || 1 0.91 0.92 -3.50 0.38 1.53 0.64 0.62 -0.01 -0.03 1.57 0.76 1.40 1.14 -2.05
4760 || orf19.3687 || || || Ortholog(s) have unfolded protein binding activity, role in cytoskeleton organization, protein folding and prefoldin complex localization || 1 0.67 1.20 1.32 1.37 1.40 1.21 0.12 0.52 0.82 1.35 1.50 0.34 0.83 -3.04
4761 || orf19.4757 || NAR1 || || Putative cytosolic iron-sulfur (FeS) protein assembly machinery protein; induced by nitric oxide; oxidative stress-induced via Cap1p || 1 0.11 -0.16 0.20 0.09 0.19 -0.02 0.39 0.07 0.27 0.11 -0.17 -0.45 -0.11 -0.21 -0.21 -0.70
4762 || orf19.5789 || ADE8 || || Putative phosphoribosylglycinamide formyl-transferase, enzyme of amino acid biosynthesis pathway; upregulated in biofilm; S. cerevisiae ortholog is Gcn4p regulated; protein enriched in stationary phase yeast-form cultures || 1 0.62 0.53 -0.05 0.01 0.09 -0.01 0.09 0.56 -0.01 0.71 0.12 -0.06 0.36 0.50 0.05 -1.05
4763 || orf19.1529 || || || Protein of unknown function; macrophage-induced gene || 1 0.21 0.51 0.14 0.78 -0.59 0.46 -0.14 1.17 0.20 0.88 0.09 -0.58 -0.37 0.81 -0.05 -2.43
4764 || orf19.6141 || HGT16 || || Putative glucose transporter of the major facilitator superfamily; the C. albicans glucose transporter family comprises 20 members; 12 probable membrane-spanning segments; gene has intron; expressed in rich medium with 2% glucose || 1 0.46 0.38 -0.14 -0.17 0.22 0.83 -0.11 0.73 0.62 0.96 -0.34 -0.45 0.03 0.39 0.27 -1.48
4765 || orf19.5049 || || || Putative U3-containing 90S preribosome processome complex subunit; Hap43-induced gene; rat catheter and Spider biofilm induced; F-12/CO2 early biofilm induced || 1 0.06 0.20 0.19 0.36 0.34 0.91 0.33 0.23 -0.03 0.97 -0.46 -0.22 0.10 0.43 -0.01 -0.90
4766 || orf19.2445 || || || Putative dicarboxylic amino acid permease; fungal-specific (no human or murine homolog); induced by alpha pheromone in SpiderM medium || 1 0.86 -0.37 0.04 0.43 1.17 0.16 0.75 0.15 0.29 -0.29 0.50 -0.49 1.69 -0.96 -2.91
4767 || orf19.4861.1 || || || Protein of unknown function || 1 0.35 0.04 -0.81 0.23 -0.08 0.31 0.61 0.06 0.07 0.31 0.12 0.48 -0.45 -1.38
4768 || orf19.2779 || || || Protein of unknown function; Hap43-repressed gene || 1 -0.29 -0.24 -0.77 0.05 -0.08 0.79 -0.10 -0.40 0.64 -0.18 -0.00 0.07 -0.49 0.38 0.14 -1.89
4769 || orf19.7208 || CSK1 || || Putative mitogen-activated protein (MAP) kinase with an unknown role; null mutant produces wrinkled colonies; similar to S. cerevisiae Smk1p, which is a protein kinase required for sporulation || 1 -0.11 -0.33 0.19 -0.04 -0.07 0.27 0.06 -0.21 0.24 0.01 0.37 -0.40 0.23 -0.37 -0.81
4770 || orf19.1270 || FRE3 || || Protein with similarity to ferric reductase Fre10p; possibly an essential gene, disruptants not obtained by UAU1 method || 1 -0.07 0.21 0.31 -0.05 -0.18 0.23 -0.08 0.14 0.29 0.19 -0.02 -0.25 -0.34 -0.43 -0.05 -1.13
4771 || orf19.2025 || || || Dubious open reading frame || 1 -0.20 1.08 -0.06 -0.31 0.21 0.47 -0.27 -0.32 -0.05 -0.12 -0.79 -0.29 0.09 -0.29 -2.22
4772 || orf19.6859 || || || Ortholog of C. dubliniensis CD36 : Cd36_44860, Candida tropicalis MYA-3404 : CTRG_04054 and Candida albicans WO-1 : CAWG_03295 || 1 0.49 1.01 -0.09 -0.66 -0.10 -0.35 -0.88 0.15 0.89 -0.53 -0.60 -0.86 -1.37
4773 || orf19.2312 || || || Protein similar to ferric reductase Fre10p; possibly an essential gene, disruptants not obtained by UAU1 method || 1 0.05 0.14 0.57 0.10 -0.27 -0.58 -1.38 -0.37 -0.04 0.21 0.01 0.67 0.12 -0.33 -2.11
4774 || orf19.257 || || || Transcription is negatively regulated by Sfu1p; repressed by nitric oxide || 1 -0.26 0.40 -0.09 -0.04 -0.53 -0.28 -0.67 -0.38 1.19 0.76 -0.24 0.90 -0.32 -1.72
4775 || orf19.937 || || || Ortholog of Candida albicans WO-1 : CAWG_04446 || 1 -0.32 0.16 0.36 -0.32 0.33 -0.22 0.01 1.31 0.64 0.30 -0.48 0.21 -0.41 0.09 -1.79
4776 || orf19.5444 || TIM44 || || Protein involved in transport across membranes; Spider biofilm repressed || 1 -0.32 0.10 0.11 -0.11 0.35 -0.23 -0.18 0.15 0.70 0.47 0.22 0.22 0.44 -0.21 0.14 -0.64
4777 || orf19.6715 || || || Ortholog of Candida albicans WO-1 : CAWG_03078 || 1 -0.25 0.11 0.12 0.41 0.87 -0.17 0.69 0.13 0.00 0.07 0.21 1.50 0.10 0.46 0.34 -3.82
4778 || orf19.4115 || || || Ortholog of Candida albicans WO-1 : CAWG_04349 || 1 0.85 0.55 -0.19 0.86 -0.28 0.28 -0.27 -1.20 0.84 2.42 -1.28 -2.53
4779 || orf19.2509 || || || Ortholog of C. parapsilosis CDC317 : CPAR2_401850, C. dubliniensis CD36 : Cd36_80970, Lodderomyces elongisporus NRLL YB-4239 : LELG_04407 and Candida orthopsilosis Co 90-125 : CORT_0E01890 || 1 -0.07 0.20 0.20 0.53 0.31 0.55 -0.10 -1.21 -0.64 0.11 1.07 -0.37 0.29
4780 || orf19.2727 || GRX3 || || Putative glutaredoxin; flucytosine induced; regulated by Gcn4p; repressed in response to amino acid starvation (3-aminotriazole treatment) || 1 0.15 0.60 -0.25 -0.26 0.24 0.10 0.23 0.24 -0.35 0.17 0.34 0.24 -0.11 -0.06 0.40 0.41
4781 || orf19.1438 || || || Protein with homology to NADH dehydrogenase; regulated by Sef1p-, Sfu1p-, and Hap43p || 1 0.17 0.44 -0.10 -0.76 0.55 0.03 -0.00 0.38 -1.00 -0.38 0.25 0.31 0.32 0.34 0.50 0.33
4782 || orf19.4321 || || || Ortholog of Candida albicans WO-1 : CAWG_04677 || 1 0.24 0.50 0.12 0.32 0.17 -0.20 0.72 -1.90 0.55 0.09 0.21 0.30 0.34
4783 || orf19.1113 || || || Ortholog of C. dubliniensis CD36 : Cd36_53540, Debaryomyces hansenii CBS767 : DEHA2G07854g, Pichia stipitis Pignal : PICST_32162 and Spathaspora passalidarum NRRL Y-27907 : SPAPADRAFT_50795 || 1 0.17 0.58 0.13 -0.46 -0.27 -0.50 -0.11 0.63 -1.88 0.55 0.90 0.83 0.59 0.08 0.65 0.35
4784 || orf19.3266 || || || Ortholog of C. dubliniensis CD36 : Cd36_25930, C. parapsilosis CDC317 : CPAR2_800910, Candida tenuis NRRL Y-1498 : CANTEDRAFT_132053 and Debaryomyces hansenii CBS767 : DEHA2E17160g || 1 -0.04 0.03 0.04 -0.05 0.32 -0.34 -0.41 0.08 -1.04 -0.29 0.47 0.27 -0.23 -0.28 0.73 0.59
4785 || orf19.1553 || ENT3 || || Putative epsin; induced during the mating process; transcript is upregulated in an RHE model of oral candidiasis || 1 0.00 -0.04 -0.05 -0.21 0.06 -0.02 -0.07 0.19 -0.38 0.08 0.11 -0.15 -0.00 -0.02 0.35 0.33
4786 || orf19.3968 || || || Protein of unknown function; flow model biofilm induced || 1 -0.12 0.31 -0.47 0.18 0.46 0.84 -1.04 0.12 0.34 -1.01 0.39 0.77
4787 || orf19.2745 || UME7 || || Putative transcription factor with zinc cluster DNA-binding motif; similar to S. cerevisiae Ume6p, which is a transcription factor involved in the regulation of meiotic genes || 1 0.35 0.82 0.88 0.56 1.42 0.68 0.39 0.57 -3.17 -0.14 0.12 -1.48 0.43 -1.27 0.36 0.69
4788 || orf19.2505 || || || Ortholog of Candida albicans WO-1 : CAWG_02437 || 1 0.30 0.02 0.35 0.54 1.16 0.59 -0.04 0.60 -0.12 0.31 -1.07 -0.62 -0.09 0.84 -0.02
4789 || orf19.3196 || || || Ortholog of Candida albicans WO-1 : CAWG_04564 || 1 0.25 -0.11 0.35 0.50 0.63 0.20 -0.13 0.08 -0.77 0.07 0.36 -0.03 -0.73 -0.58 0.44 0.14
4790 || orf19.7487 || || || Has domain(s) with predicted RNA binding, RNA-directed DNA polymerase activity and role in RNA-dependent DNA replication || 1 0.10 -0.00 0.22 0.06 0.70 -0.39 0.20 0.32 -0.73 0.14 -0.08 0.13
4791 || orf19.4214 || || || Ortholog of Candida albicans WO-1 : CAWG_05313 || 1 0.37 -0.43 0.09 0.97 0.14 0.16 -1.25 -0.58 0.71 0.32 0.33 -0.34 0.39 -0.41
4792 || orf19.3265 || TRM1 || || Putative N2,N2-dimethylguanine tRNA methyltransferase; induced upon adherence to polystyrene || 1 -0.17 -0.15 0.04 -0.23 0.28 0.22 -0.08 0.06 -0.48 0.49 0.44 0.08 0.06 0.19 0.15 -0.11
4793 || orf19.5918 || || || Ortholog of Candida albicans WO-1 : CAWG_02773 || 1 -0.51 -0.47 -0.29 0.93 0.32 -0.15 -1.69 0.78 0.41 0.17 0.47 0.28 -0.31 -0.65
4794 || orf19.6710 || UTP9 || || Small-subunit processome protein; Ssr1-induced; repressed by prostaglandins; physically interacts with TAP-tagged Nop1 || 1 -0.29 -0.17 -0.14 -0.72 0.52 0.57 0.38 0.22 -0.73 0.27 0.52 -0.46 0.08 -0.04 -0.01 -0.48
4795 || orf19.1286 || || || Ortholog of Candida albicans WO-1 : CAWG_04776 || 1 0.60 -1.27 1.16 -3.39 1.72 1.44 -0.33 -0.00 -2.89 0.11 0.67 -0.38 0.51 -0.20 0.25
4796 || orf19.2530 || || || Dubious open reading frame || 1 -0.34 0.19 1.02 -1.23 1.47 0.69 -0.13 0.18 0.01 0.59 -0.27 0.00 0.40 -0.50 0.55
4797 || orf19.5068 || IRE1 || || Putative protein kinase; role in cell wall regulation; mutant is hypersensitive to caspofungin; Spider biofilm induced || 1 0.01 0.05 0.07 -0.33 0.80 0.52 -0.73 -0.21 0.21 -0.05 -0.52 0.29 -0.03 -0.43 0.08 -0.63
4798 || orf19.6918 || || || Protein of unknown function; Hap43-induced gene; Spider biofilm induced || 1 0.15 0.12 -0.03 -0.13 0.31 0.68 0.11 -0.01 -0.32 0.09 -0.16 0.68 0.49 -0.43 0.46 -0.22
4799 || orf19.6491 || || || Ortholog of Candida albicans WO-1 : CAWG_05572 || 1 -0.21 -0.00 0.53 -0.25 0.65 1.64 -0.05 -0.26 0.68 -0.07 0.55 0.41 -0.91 1.15 0.02
4800 || orf19.6173 || STD1 || || Putative transcription factor; involved in control of glucose-regulated gene expression; repressed by Rgt1; Spider biofilm induced || 1 -0.25 -0.25 -0.03 -0.14 0.30 0.55 -0.34 -0.32 -0.09 0.42 -0.07 0.14 0.16 -0.06 0.66 -0.01
4801 || orf19.3204 || || || Ortholog of C. dubliniensis CD36 : Cd36_51610, C. parapsilosis CDC317 : CPAR2_303630, Candida tenuis NRRL Y-1498 : CANTEDRAFT_135125 and Debaryomyces hansenii CBS767 : DEHA2E19030g || 1 -0.35 -0.57 -0.63 -0.77 0.75 1.09 -0.08 -0.54 -0.37 0.92 -0.36 0.59 0.38 -0.38 0.73 -0.38
4802 || orf19.3626 || || || Ortholog(s) have cytosol, nucleus localization || 1 -0.23 -0.38 -0.22 -0.38 0.18 0.38 -0.30 -0.53 -0.26 0.49 -0.38 0.64 0.15 -0.51 0.53 -0.28
4803 || orf19.3626 || || || Ortholog(s) have cytosol, nucleus localization || 1 -0.41 -0.16 -0.23 -0.85 0.80 0.49 0.36 -0.75 -0.58 0.49 -0.39 -0.29 0.28 -0.44 0.76 -0.59
4804 || orf19.5942 || || || Zinc finger protein orthologous to S. cerevisiae Itt1; repressed by adherence to polystyrene; Spider biofilm induced || 1 0.02 -0.09 -0.06 -0.13 0.14 -0.23 0.37 0.13 0.45 -0.01 -0.53 -0.21 0.05 -0.22 0.32 -0.34
4805 || orf19.4396 || || || Mitochondrial inner membrane protein; mammalian mitofilin domain; Spider biofilm repressed || 1 -0.13 -0.31 -0.34 -0.54 0.14 -0.18 0.12 0.27 0.24 0.27 -0.39 -0.18 0.00 0.49 0.14 -0.51
4806 || orf19.6736 || || || Protein required for mitochondrial ribosome small subunit biogenesis; role in maturation of SSU-rRNA; Spider biofilm induced || 1 -0.09 0.12 -0.54 -0.71 0.17 0.16 0.40 -0.13 0.46 1.04 -0.46 -0.13 0.55 0.17 0.23 -1.06
4807 || orf19.5977 || CEM1 || || Protein similar to S. cerevisiae Cem1p, an acyl carrier protein involved in fatty acid biosynthesis; likely to be essential for growth, based on an insertional mutagenesis strategy || 1 -0.33 -0.24 -0.24 -0.56 0.65 0.63 -0.06 0.07 0.34 1.02 -0.63 -0.72 0.33 0.05 -0.04 -0.31
4808 || orf19.6594 || PLB3 || || GPI-anchored cell surface phospholipase B; possibly secreted; fungal-specific (no mammalian homolog); induced by Tbf1; fluconazole-induced; possible essential gene (UAU1 method); Spider and flow model biofilm induced || 1 -0.23 -0.14 0.12 -0.04 0.80 0.36 0.05 -0.28 0.60 0.16 -0.76 -0.41 0.45 0.06 0.30 -1.09
4809 || orf19.5749 || SBA1 || || Similar to co-chaperones; induced in high iron; farnesol-, heavy metal (cadmium) stress-induced; protein level decreases in stationary phase cultures; Hap43-repressed || 1 0.12 0.07 -0.15 -0.42 0.60 0.67 0.43 0.35 0.37 0.08 -0.17 -0.29 0.24 0.51 0.42 -0.86
4810 || orf19.3984 || || || Protein of unknown function; induced in core caspofungin response; induced in ssr1 mutant; induced by nitric oxide independent of Yhb1; Spider biofilm induced || 1 -0.11 -0.04 -0.10 -0.17 1.37 0.96 0.19 0.26 0.60 0.01 -0.42 -0.34 0.79 0.24 0.93 -0.70
4811 || orf19.3984 || || || Protein of unknown function; induced in core caspofungin response; induced in ssr1 mutant; induced by nitric oxide independent of Yhb1; Spider biofilm induced || 1 -0.14 0.08 -0.15 0.06 1.01 0.77 0.65 0.15 0.24 0.14 -0.69 -0.57 0.94 0.29 0.83 -0.61
4812 || orf19.4991 || MPT5 || || Putative RNA-binding protein; Hap43p-repressed gene; protein induced during the mating process || 1 0.10 0.12 -0.35 -0.04 0.56 0.19 0.51 0.38 0.28 0.70 -0.71 -0.64 0.10 0.36 0.80 -0.64
4813 || orf19.4279 || MNN1 || || Putative alpha-1,3-mannosyltransferase; of the mannosyltransferase complex; negatively regulated by Rim101; transcript elevated in chk1 and nik1 mutants, but not in sln1 mutant; Spider and flow model biofilm induced || 1 0.25 0.20 0.20 0.21 1.06 1.30 0.67 0.79 0.96 0.87 -0.93 -1.13 0.82 0.32 0.72 -1.11
4814 || orf19.4279 || MNN1 || || Putative alpha-1,3-mannosyltransferase; of the mannosyltransferase complex; negatively regulated by Rim101; transcript elevated in chk1 and nik1 mutants, but not in sln1 mutant; Spider and flow model biofilm induced || 1 0.42 0.57 -0.14 0.03 1.42 1.21 0.88 1.22 1.22 1.10 -1.13 -1.27 1.13 0.75 0.84 -1.45
4815 || orf19.4279 || MNN1 || || Putative alpha-1,3-mannosyltransferase; of the mannosyltransferase complex; negatively regulated by Rim101; transcript elevated in chk1 and nik1 mutants, but not in sln1 mutant; Spider and flow model biofilm induced || 1 0.09 -0.05 -0.82 -0.65 1.55 1.19 1.15 1.21 1.09 0.97 -1.37 -1.38 1.27 0.69 1.15 -1.75
4816 || orf19.4279 || MNN1 || || Putative alpha-1,3-mannosyltransferase; of the mannosyltransferase complex; negatively regulated by Rim101; transcript elevated in chk1 and nik1 mutants, but not in sln1 mutant; Spider and flow model biofilm induced || 1 -0.40 -0.45 -0.82 -0.61 1.10 1.10 0.98 0.90 0.79 0.75 -1.76 -1.34 0.98 0.69 0.94 -1.42
4817 || orf19.4279 || MNN1 || || Putative alpha-1,3-mannosyltransferase; of the mannosyltransferase complex; negatively regulated by Rim101; transcript elevated in chk1 and nik1 mutants, but not in sln1 mutant; Spider and flow model biofilm induced || 1 -0.37 -0.37 -1.25 -1.07 1.04 0.87 0.88 0.92 0.54 0.53 -1.81 -2.11 0.95 -0.00 0.80 -1.97
4818 || orf19.430 || YPT53 || || Rab-family GTPase involved in vacuolar trafficking, colocolizes with Vps1p and Ypt52p in late endosome; Hap43-repressed gene || 1 0.11 0.02 -0.33 -0.39 0.63 0.07 0.82 0.39 0.59 -0.34 -0.48 -1.00 0.98 0.09 0.72 -0.40
4819 || orf19.4722 || RTG1 || || Ortholog(s) have sequence-specific DNA binding RNA polymerase II transcription factor activity || 1 -0.16 -0.11 0.08 -0.23 0.17 0.15 0.05 0.15 0.07 -0.04 -0.12 -0.10 0.28 -0.03 0.30 -0.21
4820 || orf19.2513 || || || Ortholog of C. dubliniensis CD36 : Cd36_81010, C. parapsilosis CDC317 : CPAR2_103060, Candida tenuis NRRL Y-1498 : CANTEDRAFT_127339 and Debaryomyces hansenii CBS767 : DEHA2G01936g || 1 -0.11 -0.02 -0.24 -0.25 1.25 -0.03 0.55 -0.41 -0.23 -0.08 -0.60 -0.43 0.99 -0.46 0.11 -0.77
4821 || orf19.3470 || || || Putative flavodoxin; similar to S. cerevisiae Tyw1, an iron-sulfur protein required for synthesis of wybutosine modified tRNA; predicted Kex2p substrate; Spider biofilm induced || 1 0.02 0.28 -0.07 0.18 0.29 0.53 0.50 -0.39 0.09 1.00 -0.35 0.38 0.23 -0.26 -0.14 -0.31
4822 || orf19.3125 || || || Ortholog(s) have cytosol, nucleus localization || 1 0.11 0.19 -0.23 -0.47 0.35 0.28 -0.28 -0.32 -0.13 0.66 0.06 -0.08 0.39 0.36 -0.13 0.12
4823 || orf19.5134 || || || Ortholog of C. parapsilosis CDC317 : CPAR2_704140, C. dubliniensis CD36 : Cd36_72870, Lodderomyces elongisporus NRLL YB-4239 : LELG_05208 and Candida orthopsilosis Co 90-125 : CORT_0G04320 || 1 0.71 0.57 -0.05 -0.34 0.16 0.60 0.29 -0.06 0.07 0.61 -0.16 0.19 0.96 0.58 -0.52 0.30
4824 || orf19.1827 || || || Protein of unknown function; flow model biofilm induced; induced by alpha pheromone in SpiderM medium || 1 0.81 -0.98 0.57 -0.13 1.02 2.05 1.20 -0.64 0.59 0.46 0.38 0.12 1.11
4825 || orf19.2043 || || || Ortholog of C. dubliniensis CD36 : Cd36_15750, C. parapsilosis CDC317 : CPAR2_213000, Debaryomyces hansenii CBS767 : DEHA2D18524g and Pichia stipitis Pignal : PICST_42355 || 1 0.23 -0.40 0.14 0.04 0.38 0.31 0.09 0.03 -0.03 0.26 0.26 -0.03 0.30 -0.13 0.12 -0.17
4826 || orf19.3498 || || || Ortholog of C. dubliniensis CD36 : Cd36_62270, C. parapsilosis CDC317 : CPAR2_602240, Candida tenuis NRRL Y-1498 : CANTEDRAFT_114419 and Debaryomyces hansenii CBS767 : DEHA2E04884g || 1 0.25 0.08 0.65 0.70 0.80 0.56 -0.10 0.12 -0.10 0.16 0.56 0.29 0.10 0.15 0.10 -0.28
4827 || orf19.2721 || || || Ortholog(s) have role in ascospore formation, regulation of mitotic cell cycle, regulation of translation and cytosol, nucleus localization || 1 0.58 0.37 0.62 0.49 0.60 0.78 0.09 0.13 -0.40 0.13 0.63 0.14 0.09 -0.11 -0.05 -0.24
4828 || orf19.1958 || || || Dubious open reading frame || 1 1.00 0.19 0.65 0.77 0.76 1.41 -0.04 -0.50 -0.32 1.04 0.69 0.32 0.59 -0.06 -1.19
4829 || orf19.2032 || || || Protein of unknown function; rat catheter biofilm induced || 1 0.86 0.72 0.03 0.60 0.04 0.28 0.39 0.32 0.09 -0.07 1.32 -0.19 -0.05 0.12 0.15 -0.70
4830 || orf19.6897 || || || Protein of unknown function || 1 1.03 -0.09 0.18 0.57 0.07 0.65 0.08 -0.11 0.07 -0.31 0.44 -0.41 -0.26 -0.11 0.36 -1.29
4831 || orf19.4896 || RPA34 || || Putative RNA polymerase I subunit; rat catheter biofilm induced || 1 0.07 0.17 0.19 0.32 0.26 0.48 0.14 0.14 -0.08 0.74 0.27 -0.50 0.27 -0.39 0.04 -0.81
4832 || orf19.4143 || FYV5 || || Protein with a predicted role maturation of 18S rRNA; rat catheter biofilm induced || 1 0.66 0.60 0.82 0.33 0.80 0.94 0.69 0.17 0.07 0.93 0.79 -0.19 0.56 0.13 0.45 -2.74
4833 || orf19.4239 || || || Planktonic growth-induced gene || 1 0.61 0.82 -0.00 0.22 0.85 1.21 1.12 -0.47 -0.40 2.03 -1.15 1.61 -0.50 1.21 -2.89
4834 || orf19.2711.1 || MED20 || || Subunit of the RNA polymerase II mediator complex; involved in control of filamentous growth and Spider biofilm formation; rat catheter biofilm repressed || 1 0.05 -0.04 0.03 0.16 0.08 0.14 0.25 0.17 -0.22 0.04 0.33 0.01 0.14 0.13 -0.02 -0.35
4835 || orf19.7291 || || || Ortholog(s) have tRNA (adenine-N1-)-methyltransferase activity, role in tRNA methylation and cytosol, nucleus, tRNA (m1A) methyltransferase complex localization || 1 -0.14 -0.09 0.25 0.39 0.28 0.41 0.01 0.29 -0.32 -0.10 0.67 -0.25 0.78 -0.03 -0.05 -0.47
4836 || orf19.5704 || || || Ortholog(s) have rRNA binding activity, role in mitochondrial RNA processing, mitochondrial genome maintenance, rRNA metabolic process and mitochondrion localization || 1 0.09 0.24 0.25 -0.70 1.19 0.96 0.17 1.36 -0.24 0.71 0.21 -0.48 1.08 -0.06 0.45
4837 || orf19.2585 || || || Ortholog of Candida albicans WO-1 : CAWG_01548 || 1 0.33 0.61 0.11 -1.12 1.41 0.51 0.60 0.43 0.30 0.10 -0.22 0.95 -0.43 0.50
4838 || orf19.4225 || LEU3 || || Zn(II)2Cys6 transcription factor; predicted regulator branched-c ofhain amino acid biosynthesis genes; alkaline induced; induced by Mnl1 under weak acid stress; required for yeast cell adherence to silicone substrate; Spider biofilm induced || 1 0.54 0.52 0.01 -0.33 0.77 0.48 0.28 0.14 0.04 -0.26 0.20 -0.48 0.80 -0.28 0.27 -0.76
4839 || orf19.3370 || DOT4 || || Protein similar to ubiquitin C-terminal hydrolase; localizes to cell surface of hyphal cells, but not yeast-form cells; repressed upon high-level peroxide; Hap43p-induced; rat catheter biofilm induced || 1 0.72 0.37 0.05 0.07 0.38 0.46 0.34 0.41 -0.01 0.76 -0.10 -0.41 1.37 -0.35 -0.04 -0.53
4840 || orf19.2501 || FLC1 || || Protein involved in heme uptake; putative FAD transporter, similar to S. cerevisiae Flc1; regulated by iron; macrophage-induced; mutant defective in filamentous growth; Spider biofilm induced || 1 0.33 0.36 -0.26 -0.08 0.40 -0.01 0.38 0.05 0.08 0.61 -0.09 -0.35 0.69 1.01 -0.12 -0.28
4841 || orf19.3756 || CHR1 || || Predicted DEAD-box ATP-dependent RNA helicase; functional homolog of S. cerevisiae Rok1; Hap43-induced; Spider biofilm induced || 1 0.83 1.10 0.47 0.09 0.87 1.32 0.43 0.40 -0.17 0.58 -0.19 -0.43 1.09 1.95 0.36 -0.94
4842 || orf19.2859 || SRP40 || || Putative chaperone of small nucleolar ribonucleoprotein particles; macrophage/pseudohyphal-induced; rat catheter biofilm induced || 1 0.13 0.35 -0.43 0.26 -0.19 0.96 0.44 0.34 -0.27 0.93 0.50 -0.40 0.59 1.12 0.03 -0.37
4843 || orf19.172 || RPC19 || || Putative RNA polymerases I and III subunit AC19; Hap43-induced; rat catheter biofilm induced || 1 0.23 0.34 -0.07 -0.20 -0.14 0.41 0.16 0.12 -0.64 1.02 0.32 -0.37 0.51 0.71 -0.10 -0.88
4844 || orf19.4963 || || || Ortholog(s) have role in ER-associated ubiquitin-dependent protein catabolic process and cytoplasm, nucleolus localization || 1 0.34 1.11 -0.25 0.10 0.88 0.28 0.00 0.53 -0.68 1.55 0.64 0.27 0.85 0.37 -0.19 -0.84
4845 || orf19.6346 || || || Putative nuclear export protein; Hap43p-induced gene; decreased transcription is observed in an azole-resistant strain that overexpresses MDR1 || 1 0.20 0.34 0.07 0.02 0.26 0.26 0.00 0.06 -0.13 0.86 0.46 -0.01 0.39 -0.09 -0.10 -0.33
4846 || orf19.2643 || RPO26 || || Putative RNA polymerase subunit; heterozygous null mutant exhibits resistance to parnafungin in the C. albicans fitness test || 1 -0.07 0.22 0.31 0.03 0.41 0.58 0.05 0.09 -0.25 0.76 0.20 0.17 0.19 0.15 -0.02 -0.46
4847 || orf19.5627 || || || S. cerevisiae ortholog Hek2/Khd1 is a putative RNA binding protein involved in the asymmetric localization of ASH1 mRNA; Hap43-induced gene || 1 -0.01 0.05 -0.38 -0.16 0.81 0.96 0.19 0.22 -0.70 0.60 0.50 0.14 0.75 0.17 1.20 -0.34
4848 || orf19.2538 || PTC2 || || Protein phosphatase of the Type 2C-related family (serine/threonine-specific) with a potential role in DNA damage checkpoint control; localizes to both cytoplasm and mitochondria; mutant shows virulence defect || 1 0.26 0.42 -0.15 -0.13 0.17 0.38 0.27 0.09 -0.43 0.44 0.24 0.11 0.42 0.67 0.32 -0.27
4849 || orf19.1082 || || || Protein with an Alba DNA/RNA-binding protein domain; Spider biofilm induced || 1 2.26 0.66 0.74 -0.49 1.49 1.57 0.52 1.26 -0.44 1.58 -0.01 0.22 0.53 1.14 0.93 0.09
4850 || orf19.2829 || || || Ortholog(s) have role in protein transport and endoplasmic reticulum, nuclear envelope localization || 1 1.22 0.70 0.16 0.56 0.86 0.50 0.62 0.79 -0.47 1.50 0.10 0.32 0.14 0.62 0.54 -0.20
4851 || orf19.5905 || || || Protein of unknown function; Hap43-induced; F-12/CO2 early biofilm induced || 1 0.72 0.72 0.72 0.59 0.42 0.58 0.60 0.39 -0.15 0.81 0.10 0.14 0.52 0.51 0.53 -0.20
4852 || orf19.5905 || || || Protein of unknown function; Hap43-induced; F-12/CO2 early biofilm induced || 1 0.97 0.71 0.46 -0.07 0.57 0.62 1.46 0.81 -0.15 1.62 -0.10 0.20 0.88 0.81 0.54 -0.64
4853 || orf19.158 || || || Ortholog of S. cerevisiae Apd1; required for normal localization of actin patches and normal tolerance of sodium ions and hydrogen peroxide; Hap43-induced; Spider biofilm induced || 1 -0.06 0.28 0.04 -0.89 0.30 0.47 1.01 0.50 0.12 1.15 0.44 -0.17 0.62 1.07 0.53 0.09
4854 || orf19.5905 || || || Protein of unknown function; Hap43-induced; F-12/CO2 early biofilm induced || 1 0.09 0.46 -0.49 -0.54 0.21 0.53 1.16 0.51 0.31 1.73 0.03 0.32 0.48 0.84 0.53 -0.38
4855 || orf19.2740 || || || Ortholog(s) have 5'-flap endonuclease activity || 1 0.43 0.29 -0.22 0.13 0.87 0.33 1.33 0.54 -0.06 1.31 0.47 0.02 0.18 0.15 1.03 0.21
4856 || orf19.4896 || RPA34 || || Putative RNA polymerase I subunit; rat catheter biofilm induced || 1 0.38 0.65 -0.47 -0.33 0.72 0.61 1.03 1.06 -0.56 1.22 1.62 -0.39 1.16 -0.07 0.44 -0.44
4857 || orf19.2998 || TSR2 || || Protein with a predicted role in pre-rRNA processing; repressed by prostaglandins || 1 0.80 1.10 -0.21 -0.45 1.00 0.46 1.09 1.02 0.05 1.95 1.44 -0.15 0.90 0.74 0.60 0.12
4858 || orf19.1633 || UTP4 || || Putative U3 snoRNA-associated protein; Hap43-induced; physically interacts with TAP-tagged Nop1; Spider biofilm induced || 1 0.65 0.56 -0.61 -0.22 1.02 0.53 0.70 1.07 -0.18 1.68 0.63 -0.75 0.70 0.46 0.37 -0.09
4859 || orf19.2715 || RPC53 || || Ortholog(s) have RNA polymerase III activity, role in tRNA transcription from RNA polymerase III promoter and DNA-directed RNA polymerase III complex localization || 1 0.29 0.05 -0.20 -0.36 0.45 0.77 0.52 0.26 0.01 1.12 0.32 -0.19 0.05 0.29 0.38 -0.10
4860 || orf19.7291 || || || Ortholog(s) have tRNA (adenine-N1-)-methyltransferase activity, role in tRNA methylation and cytosol, nucleus, tRNA (m1A) methyltransferase complex localization || 1 -0.21 0.06 -0.61 -0.88 0.75 1.47 0.86 0.51 -0.23 1.58 0.58 0.66 0.44 0.88 0.87 -0.19
4861 || orf19.6477 || || || Ortholog(s) have tRNA (guanine-N7-)-methyltransferase activity, role in tRNA methylation and cytosol, nucleus, tRNA methyltransferase complex localization || 1 0.32 0.31 -0.34 -0.25 0.87 1.16 0.46 0.30 -0.45 0.99 0.18 0.29 0.77 0.06 0.60 -0.18
4862 || orf19.4563 || || || Protein of unknown function; repressed by prostaglandins; Hap43-induced, Spider biofilm induced || 1 0.27 -0.01 -0.04 -0.23 1.04 1.29 0.62 0.46 -0.06 1.61 -0.01 -0.03 0.98 0.54 0.74 -0.27
4863 || orf19.3204 || || || Ortholog of C. dubliniensis CD36 : Cd36_51610, C. parapsilosis CDC317 : CPAR2_303630, Candida tenuis NRRL Y-1498 : CANTEDRAFT_135125 and Debaryomyces hansenii CBS767 : DEHA2E19030g || 1 0.31 -0.09 -0.22 0.36 0.78 1.00 0.27 0.23 -0.27 1.30 0.45 0.01 1.38 0.40 0.90 -0.06
4864 || orf19.4273 || || || Putative mitochondrial membrane protein; ortholog of S. cerevisiae Sls1; coordinates expression of mitochondrially-encoded genes; Hap43-induced || 1 -0.06 0.30 0.05 -0.61 0.72 0.75 0.68 0.35 0.20 1.75 0.58 0.11 1.15 0.25 0.77 -0.01
4865 || orf19.7332 || ELF1 || || Putative mRNA export protein; Walker A and B (ATP/GTP binding) motifs; required for wild-type morphology, growth; expressed in hyphal, pseudohyphal, and yeast form; Hap43-induced; Spider and flow model biofilm induced || 1 0.50 0.54 -0.28 0.07 0.82 1.32 1.28 0.59 -0.32 1.64 1.20 0.31 1.25 1.10 0.39 0.51
4866 || orf19.6903 || || || Predicted RNA polymerase III subunit C37; Spider biofilm induced || 1 0.73 0.63 -0.19 -0.01 0.45 0.21 0.76 0.21 0.14 1.10 0.33 -0.10 0.83 0.12 0.71 -0.26
4867 || orf19.2934 || || || Similar to S. cerevisiae Bud20; predicted role in cellular bud site selection; rat catheter and Spider biofilm induced || 1 1.86 1.99 -0.37 0.00 1.80 1.58 1.67 0.75 0.06 1.26 0.43 0.29 1.89 0.20 1.15 -1.69
4868 || orf19.81 || || || Ortholog(s) have role in exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA and LSU-rRNA), more || 1 0.07 0.60 -0.02 -0.35 0.62 0.83 0.51 0.03 -0.47 0.86 0.33 0.17 0.37 0.29 0.69 -0.59
4869 || orf19.2287 || RPA12 || || Putative DNA-directed RNA polymerase I; induced upon adherence to polystyrene || 1 0.72 0.56 -0.02 0.09 0.91 0.87 0.83 0.78 -0.47 1.39 0.77 0.09 0.37 0.11 0.63 -1.28
4870 || orf19.2287 || RPA12 || || Putative DNA-directed RNA polymerase I; induced upon adherence to polystyrene || 1 0.60 0.53 -0.70 -0.41 0.82 0.81 0.76 0.82 -0.98 1.50 0.56 -0.50 0.36 0.19 0.64 -1.25
4871 || orf19.5500 || MAK16 || || Putative constituent of 66S pre-ribosomal particles; Hap43-induced; repressed by prostaglandins; Spider biofilm induced || 1 0.25 0.32 -0.67 -0.76 1.10 1.15 1.55 0.68 -0.25 1.71 0.50 -0.52 1.35 0.21 1.37 -1.38
4872 || orf19.6477 || || || Ortholog(s) have tRNA (guanine-N7-)-methyltransferase activity, role in tRNA methylation and cytosol, nucleus, tRNA methyltransferase complex localization || 1 -0.06 0.25 -0.61 -0.20 0.77 0.76 0.52 -0.05 -0.15 1.20 0.17 -0.16 0.67 0.02 0.49 -1.10
4873 || orf19.7194 || || || Protein required for virulence in reconstituted human epithelium (RHE) model of ex vivo infection; decreased transcription is observed upon fluphenazine treatment; induced upon adherence to polystyrene || 1 0.57 0.49 -0.22 0.04 1.10 0.41 1.16 0.13 -0.47 0.67 0.32 0.69 0.61 -0.15 1.17 -0.51
4874 || orf19.544 || RPR2 || || Ortholog(s) have ribonuclease P activity, role in intronic box C/D snoRNA processing and cytosol, nucleolar ribonuclease P complex localization || 1 0.28 0.16 0.05 -0.06 0.80 0.26 0.20 0.16 -0.67 0.63 0.32 0.46 0.02 0.05 0.29 0.06
4875 || orf19.4681 || RAT1 || || 5'-->3' exoribonuclease; similar to S. cerevisiae nuclear exoribonuclease Rat1p; suppresses S. cerevisiae kem1 mutant slow growth, mating defect, and haploid invasive growth defect || 1 0.50 0.70 -0.15 -0.36 1.13 1.42 0.43 -0.05 -0.50 0.80 0.61 0.31 0.24 0.32 0.42 -0.03
4876 || orf19.4681 || RAT1 || || 5'-->3' exoribonuclease; similar to S. cerevisiae nuclear exoribonuclease Rat1p; suppresses S. cerevisiae kem1 mutant slow growth, mating defect, and haploid invasive growth defect || 1 0.78 0.68 -0.45 -0.90 1.22 1.18 -0.11 0.22 -0.37 0.65 0.70 0.11 0.30 0.24 0.66 -0.10
4877 || orf19.6074 || HBR1 || || Essential protein involved in regulation of MTL gene expression; hemoglobin-regulated inhibitor of white-opaque switching, may affect survival in host; activator of MTLalpha1 and MTLalpha2; transcript activated by hemoglobin || 1 0.15 0.25 -0.44 -0.60 0.87 1.17 0.04 0.23 -0.71 0.51 0.80 0.07 0.06 0.18 0.51 -0.25
4878 || orf19.6074 || HBR1 || || Essential protein involved in regulation of MTL gene expression; hemoglobin-regulated inhibitor of white-opaque switching, may affect survival in host; activator of MTLalpha1 and MTLalpha2; transcript activated by hemoglobin || 1 0.26 0.31 -0.29 -0.46 1.14 1.24 0.12 0.64 -0.27 0.83 0.91 0.29 -0.06 0.35 0.48 -0.13
4879 || orf19.6110 || || || Ortholog of Candida albicans WO-1 : CAWG_01361 || 1 0.48 0.54 -0.49 -0.16 0.91 0.97 0.28 0.28 0.02 1.00 1.08 0.25 0.07 0.12 0.27 0.39
4880 || orf19.6346 || || || Putative nuclear export protein; Hap43p-induced gene; decreased transcription is observed in an azole-resistant strain that overexpresses MDR1 || 1 0.46 0.47 -0.67 -0.56 0.87 0.73 0.15 0.54 -0.82 0.84 1.43 0.31 0.28 -0.06 0.61 0.47
4881 || orf19.2643 || RPO26 || || Putative RNA polymerase subunit; heterozygous null mutant exhibits resistance to parnafungin in the C. albicans fitness test || 1 0.50 0.56 -0.20 -0.19 0.72 0.42 0.18 0.31 -0.67 0.66 0.66 0.14 0.15 -0.26 0.12 0.08
4882 || orf19.4188 || NMD5 || || Karyopherin; carrier protein involved in nuclear import of proteins; repressed in core stress response; Hap43-induced; Spider biofilm induced || 1 0.29 0.39 -0.38 -0.14 0.74 0.54 -0.04 0.06 -0.33 1.03 0.32 0.25 -0.26 -0.25 0.33 0.07
4883 || orf19.4188 || NMD5 || || Karyopherin; carrier protein involved in nuclear import of proteins; repressed in core stress response; Hap43-induced; Spider biofilm induced || 1 0.14 0.41 -0.79 -0.51 0.63 0.61 0.25 -0.15 -0.61 1.00 0.33 -0.08 -0.19 -0.10 0.31 0.08
4884 || orf19.1566 || UTP21 || || Putative U3 snoRNP protein; Hap43-induce; physically interacts with TAP-tagged Nop1; Spider biofilm induced || 1 0.05 0.14 -0.51 -0.37 0.62 0.50 -0.23 0.12 -0.67 0.69 0.37 -0.41 0.02 0.09 -0.14 0.33
4885 || orf19.7599 || UTP5 || || Putative U3 snoRNA-associated protein; Hap43p-induced gene; mutation confers resistance to 5-fluorocytosine (5-FC), 5-fluorouracil (5-FU), and tubercidin (7-deazaadenosine); physically interacts with TAP-tagged Nop1p || 1 -0.27 0.09 -0.53 -0.30 0.83 0.99 -0.11 0.22 -0.81 0.98 0.46 -0.63 -0.06 -0.20 -0.33 0.08
4886 || orf19.3091 || || || Protein of unknown function; repressed during core stress response || 1 0.01 0.09 -0.24 -0.42 0.52 0.46 -0.29 -0.02 -0.28 0.42 0.25 -0.25 0.16 -0.08 -0.30 -0.16
4887 || orf19.1047 || ERB1 || || Protein with a predicted role in ribosomal large subunit biogenesis; mutation confers hypersensitivity to 5-fluorocytosine (5-FC), 5-fluorouracil (5-FU), and tubercidin (7-deazaadenosine); hyphal, macrophage repressed || 1 0.81 0.45 -0.34 -0.34 1.18 1.48 -0.24 0.15 -1.15 0.55 0.47 -0.99 -0.38 -0.75 -0.71 -0.52
4888 || orf19.3585 || || || Putative tRNA methyltransferase complex subunit; regulated by Gcn4; repressed in response to amino acid starvation (3-aminotriazole treatment); Spider biofilm induced || 1 0.48 0.48 -0.28 -0.66 1.16 1.06 -0.27 -0.17 -0.81 0.27 0.41 -0.64 0.15 -0.11 -0.26 -0.37
4889 || orf19.6234 || || || Putative U2 snRNP component; mutation confers hypersensitivity to 5-fluorocytosine (5-FC), 5-fluorouracil (5-FU), and tubercidin (7-deazaadenosine); Hap43-induced, Spider biofilm induced || 1 0.33 0.31 -0.98 -0.67 1.16 1.66 0.06 -0.16 -1.48 1.11 0.25 -0.59 0.48 0.52 0.03 -0.25
4890 || orf19.6355 || || || Ortholog(s) have role in ribosome biogenesis and cytosol, nucleolus localization || 1 0.31 -0.06 -0.10 -0.34 0.64 0.88 0.04 0.11 -1.31 0.69 0.27 -0.92 -0.28 0.13 -0.71 -0.65
4891 || orf19.3478 || NIP7 || || Putative nucleolar protein with role in ribosomal assembly; hyphal-induced; Hap43-induced; Spider biofilm induced || 1 0.47 0.20 -0.09 -0.17 0.43 0.66 0.01 0.24 -1.07 1.02 -0.20 -1.01 -0.15 0.15 -0.34 -0.59
4892 || orf19.3478 || NIP7 || || Putative nucleolar protein with role in ribosomal assembly; hyphal-induced; Hap43-induced; Spider biofilm induced || 1 0.31 0.33 -0.28 -0.21 0.45 0.75 -0.04 0.29 -0.94 1.10 0.17 -1.02 0.09 0.66 -0.12 -0.74
4893 || orf19.7635 || DRS1 || || Putative nucleolar DEAD-box protein; Hap43-induced; mutation confers hypersensitivity to 5-fluorouracil (5-FU), tubercidin (7-deazaadenosine); Tbf1-induced; repressed in core stress response || 1 0.37 0.61 -0.35 -0.89 1.03 1.34 -0.01 0.33 -1.00 0.77 -0.09 -1.41 -0.20 0.31 -0.16 -0.34
4894 || orf19.6418 || || || Ortholog(s) have role in ribosomal large subunit biogenesis and cytoplasm, nucleus localization || 1 0.50 0.49 -0.33 -0.45 0.68 0.91 -0.06 0.05 -0.76 0.81 -0.23 -1.21 -0.37 0.28 0.03 -0.78
4895 || orf19.4479 || || || Putative U3-containing 90S preribosome subunit; Hap43-induced; repressed in core stress response; Spider biofilm induced || 1 0.73 0.41 -0.57 -0.72 1.11 1.43 -0.07 -0.37 -1.16 1.40 -0.70 -1.41 -0.61 0.14 -0.35 -0.45
4896 || orf19.1687 || || || Ortholog of S. cerevisiae Prp43, an RNA helicase in the DEAH-box family that functions in both RNA polymerase I and polymerase II transcript metabolism; Hap43-induced gene || 1 0.29 0.22 -0.22 -0.43 0.91 1.27 -0.09 -0.10 -0.91 1.02 -0.11 -1.01 0.11 -0.19 -0.29 -0.08
4897 || orf19.1687 || || || Ortholog of S. cerevisiae Prp43, an RNA helicase in the DEAH-box family that functions in both RNA polymerase I and polymerase II transcript metabolism; Hap43-induced gene || 1 -0.05 -0.07 -0.04 -0.49 0.66 1.15 -0.02 -0.14 -0.76 1.07 -0.10 -0.97 -0.31 0.00 -0.29 -0.11
4898 || orf19.5106 || DIP2 || || Putative small ribonucleoprotein complex; Tn mutation affects filamentous growth; physically interacts with TAP-tagged Nop1; heterozygous null mutant exhibits resistance to parnafungin; Hap43-induced gene; Spider biofilm induced || 1 0.26 0.27 -0.60 -0.62 0.86 1.42 -0.02 -0.63 -0.93 0.97 -0.04 -0.78 -0.25 -0.33 0.23 -0.25
4899 || orf19.2143 || || || Ortholog(s) have role in endocytic recycling and cytosol, endosome, nucleus localization || 1 0.09 0.15 -0.10 -0.30 1.10 1.20 -0.14 0.03 -0.62 0.74 0.22 -0.29 -0.22 0.04 0.25 -0.44
4900 || orf19.5912 || MAK21 || || Putative 66S pre-ribosomal particle subunit; mutation confers hypersensitivity to tubercidin (7-deazaadenosine) || 1 0.51 0.44 -0.25 -0.26 1.53 1.78 0.11 0.62 -0.45 1.30 0.20 -0.33 -0.13 0.26 0.08 0.72
4901 || orf19.6648 || SDA1 || || Predicted nuclear protein involved in actin cytoskeleton organization, passage through Start, 60S ribosome biogenesis; rat catheter biofilm induced; Hap43-induced || 1 0.60 0.75 -0.24 0.17 1.12 1.30 0.04 0.82 -0.62 1.38 0.18 -0.69 -0.31 -0.16 0.13 -0.05
4902 || orf19.3540 || MAK5 || || Putative nucleolar DEAD-box RNA helicase; oxidative stress-repressed via Cap1; repressed by prostaglandins || 1 0.57 0.81 -0.19 -0.10 1.06 1.34 -0.28 0.63 -0.89 1.20 0.54 -0.58 -0.19 -0.36 0.19 0.22
4903 || orf19.3015 || ARX1 || || Putative ribosomal large subunit biogenesis protein; repressed in core stress response; repressed by prostaglandins || 1 0.51 0.65 -0.54 -0.09 0.95 0.91 -0.08 0.58 -0.98 1.22 0.24 -0.66 -0.26 0.03 0.00 0.30
4904 || orf19.3540 || MAK5 || || Putative nucleolar DEAD-box RNA helicase; oxidative stress-repressed via Cap1; repressed by prostaglandins || 1 0.55 0.53 -0.28 -0.13 0.92 1.27 -0.18 0.29 -0.93 1.22 0.40 -0.58 -0.04 0.69 0.04 -0.06
4905 || orf19.6648 || SDA1 || || Predicted nuclear protein involved in actin cytoskeleton organization, passage through Start, 60S ribosome biogenesis; rat catheter biofilm induced; Hap43-induced || 1 0.65 0.80 -0.02 -0.42 1.22 1.16 0.32 0.59 -0.53 1.35 0.37 -0.76 0.08 0.49 0.18 -0.21
4906 || orf19.7635 || DRS1 || || Putative nucleolar DEAD-box protein; Hap43-induced; mutation confers hypersensitivity to 5-fluorouracil (5-FU), tubercidin (7-deazaadenosine); Tbf1-induced; repressed in core stress response || 1 0.66 0.85 -0.17 -0.56 1.55 1.63 0.21 0.27 -1.00 0.93 0.09 -1.05 0.05 0.31 -0.19 0.17
4907 || orf19.1915 || MPP10 || || Putative SSU processome and 90S preribosome component; repressed in core stress response; repressed by prostaglandins || 1 0.49 0.37 0.03 -0.16 1.26 1.37 0.03 0.06 -0.71 0.83 0.11 -0.74 -0.09 -0.09 0.05 -0.13
4908 || orf19.5106 || DIP2 || || Putative small ribonucleoprotein complex; Tn mutation affects filamentous growth; physically interacts with TAP-tagged Nop1; heterozygous null mutant exhibits resistance to parnafungin; Hap43-induced gene; Spider biofilm induced || 1 0.45 0.43 -0.40 -0.17 1.15 1.27 0.26 -0.20 -0.53 0.91 0.02 -0.97 0.24 -0.10 0.17 -0.15
4909 || orf19.3300 || ZPR1 || || Protein with putative zinc finger; regulated by Gcn4p; repressed in response to amino acid starvation (3-aminotriazole treatment); upregulation correlates with clinical development of fluconazole resistance || 1 0.54 0.22 -0.33 0.00 1.27 1.16 -0.37 0.34 -0.75 0.88 0.04 -0.66 0.05 -0.16 0.24 -0.14
4910 || orf19.4746 || JIP5 || || Ortholog of S. cerevisiae Jip5; predicted role in biogenesis of the large ribosomal subunit; repressed in core stress response; Hap43-induced gene || 1 0.79 0.48 -0.20 -0.06 0.84 1.37 -0.26 0.04 -0.46 1.06 0.22 -0.31 -0.13 -0.03 -0.57 -0.11
4911 || orf19.7384 || NOG1 || || Putative GTPase; mutation confers hypersensitivity to 5-fluorocytosine (5-FC), 5-fluorouracil (5-FU), and tubercidin (7-deazaadenosine); repressed by prostaglandins; Hap43-induced || 1 0.98 0.91 0.39 0.44 1.16 1.10 -0.24 0.40 -1.21 1.24 -0.07 -1.15 0.07 0.06 -0.28 0.19
4912 || orf19.6989 || || || Putative U2 snRNP-associated protein; Spider biofilm induced || 1 0.46 0.72 0.62 0.30 1.36 1.38 0.42 0.22 -0.43 0.69 0.49 0.10 0.29 -0.27 0.42 -1.02
4913 || orf19.5732 || NOG2 || || Putative nucleolar GTPase; repressed by prostaglandins; Hap43-induced, rat catheter and Spider biofilm induced || 1 1.03 0.60 0.44 0.29 1.18 1.65 0.37 -0.54 -0.60 0.80 -1.18 -1.26 0.36 -0.51 -0.34 -2.14
4914 || orf19.475 || || || Putative rRNA processing protein; rat catheter biofilm induced || 1 0.71 0.56 0.38 0.03 1.11 1.32 0.14 -0.55 -0.77 0.56 -0.52 -0.90 0.41 -0.18 -0.25 -1.27
4915 || orf19.3630 || RRP8 || || Ribosomal protein; Hap43-induced; F-12/CO2 early biofilm and rat catheter biofilm induced || 1 1.10 0.97 0.01 0.02 1.37 1.59 0.44 -0.68 -0.94 0.65 -0.75 -0.93 0.53 0.16 -0.15 -2.15
4916 || orf19.563 || RRP15 || || Putative nucleolar protein; constituent of pre-60S ribosomal particles; Hap43-induced; repressed by prostaglandins || 1 1.30 1.40 0.49 0.15 1.34 1.40 0.85 0.05 -0.74 1.09 -0.31 -1.75 0.90 0.12 -0.17 -1.91
4917 || orf19.6589 || SSF1 || || Protein involved in ribosome biogenesis; ortholog of S. cerevisiae Ssf1; Hap43-induced; rat catheter and Spider biofilm induced || 1 0.75 0.84 -0.14 0.12 1.20 1.61 0.69 0.18 -0.80 1.11 -0.36 -1.13 0.50 0.38 -0.32 -1.11
4918 || orf19.6886 || || || Ortholog(s) have rRNA binding activity, role in maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA), ribosomal large subunit export from nucleus and nucleolus localization || 1 0.98 0.70 0.37 0.34 1.07 1.53 0.14 -0.01 -0.71 1.00 -0.72 -1.30 0.30 0.13 0.02 -0.99
4919 || orf19.3088 || || || bZIP transcription factor; possibly transcriptionally regulated upon hyphal formation; Hap43; F-12/CO2 early biofilm induced; Spider biofilm induced || 1 1.00 1.36 0.30 0.22 1.04 1.68 0.34 -0.19 -1.15 0.58 -0.28 -1.33 0.52 -0.74 -0.31 -1.44
4920 || orf19.661 || KRR1 || || Putative nucleolar protein; repressed benomyl treatment or in an azole-resistant strain that overexpresses MDR1; F-12/CO2 early biofilm induced || 1 1.05 1.12 -0.37 -0.29 2.07 2.21 0.49 0.14 -1.11 0.99 0.24 -2.02 0.99 -0.28 0.37 -1.30
4921 || orf19.59 || REI1 || || Putative cytoplasmic pre-60S factor; Hap43-induced; repressed by prostaglandins || 1 0.62 0.73 -0.01 -0.41 0.99 2.00 0.52 -0.17 -0.61 1.24 -0.12 -0.88 0.61 -0.17 0.02 -1.65
4922 || orf19.5959 || NOP14 || || Putative nucleolar protein; Hap43-induced; mutation confers resistance to 5-fluorocytosine (5-FC), 5-fluorouracil (5-FU), and tubercidin (7-deazaadenosine); heterozygous mutant is resistant to parnafungin; Spider biofilm induced || 1 0.68 0.52 -0.19 -0.43 1.08 1.53 0.13 -0.20 -0.95 1.09 0.03 -0.80 0.19 -0.30 0.24 -1.08
4923 || orf19.5959 || NOP14 || || Putative nucleolar protein; Hap43-induced; mutation confers resistance to 5-fluorocytosine (5-FC), 5-fluorouracil (5-FU), and tubercidin (7-deazaadenosine); heterozygous mutant is resistant to parnafungin; Spider biofilm induced || 1 0.29 0.54 0.18 -0.24 1.20 1.51 0.24 -0.21 -0.54 1.28 0.06 -0.60 0.33 -0.13 0.06 -0.75
4924 || orf19.7197 || || || Putative intranuclear transport and DNA replication mediator; heterozygous null mutant exhibits resistance to parnafungin in the C. albicans fitness test; Spider biofilm induced || 1 0.72 0.25 -0.47 -0.87 1.43 1.54 0.26 -0.31 -0.94 1.46 -0.03 -1.26 0.57 0.24 0.20 -0.75
4925 || orf19.76 || SPB1 || || Putative AdoMet-dependent methyltransferase; Hap43-induced; repressed by prostaglandins; possibly essential gene, disruptants not obtained by UAU1 method; Spider biofilm induced || 1 1.17 1.36 0.22 -0.14 1.15 1.83 -0.15 -0.20 -0.68 1.12 0.09 -1.11 0.30 -0.36 -0.18 -0.46
4926 || orf19.124 || CIC1 || || Putative proteasome-interacting protein; rat catheter biofilm induced || 1 1.36 1.23 -0.26 -0.28 1.44 1.48 0.81 0.31 -1.16 0.95 0.29 -1.06 0.74 0.30 0.06 -0.73
4927 || orf19.76 || SPB1 || || Putative AdoMet-dependent methyltransferase; Hap43-induced; repressed by prostaglandins; possibly essential gene, disruptants not obtained by UAU1 method; Spider biofilm induced || 1 1.55 1.50 -0.13 -0.41 1.67 1.51 0.58 -0.17 -1.28 1.28 0.27 -1.39 0.75 -0.13 0.34 -1.17
4928 || orf19.76 || SPB1 || || Putative AdoMet-dependent methyltransferase; Hap43-induced; repressed by prostaglandins; possibly essential gene, disruptants not obtained by UAU1 method; Spider biofilm induced || 1 1.68 1.67 0.10 -0.11 1.62 1.85 0.58 -0.07 -1.04 1.44 0.29 -0.94 0.51 0.07 0.32 -0.66
4929 || orf19.76 || SPB1 || || Putative AdoMet-dependent methyltransferase; Hap43-induced; repressed by prostaglandins; possibly essential gene, disruptants not obtained by UAU1 method; Spider biofilm induced || 1 1.45 1.30 0.46 0.38 1.60 1.77 0.25 -0.02 -0.90 1.16 0.25 -0.71 0.42 -0.06 0.25 -0.87
4930 || orf19.6014 || RRS1 || || Putative ribosome biogenesis and nuclear export protein; Hap43p-induced gene; mutation confers hypersensitivity to 5-fluorocytosine (5-FC), 5-fluorouracil (5-FU), and tubercidin (7-deazaadenosine) || 1 0.71 1.02 0.70 0.64 1.00 1.30 0.18 0.53 -0.30 1.09 0.45 -0.69 0.76 0.49 0.23 -0.74
4931 || orf19.4191 || RLP24 || || Putative ribosomal protein; Hap43-induced; essential gene; heterozygous mutation confers hypersensitivity to 5-fluorocytosine (5-FC), 5-fluorouracil (5-FU), and tubercidin (7-deazaadenosine); Spider biofilm induced || 1 1.16 1.24 0.83 0.51 1.78 1.81 0.59 0.77 -0.18 1.33 0.61 -0.96 1.20 0.14 0.37 -0.77
4932 || orf19.2504 || BMS1 || || Putative GTPase; Hap43-induced gene; mutation confers resistance to 5-fluorocytosine (5-FC); flucytosine induced; repressed by prostaglandins; Spider biofilm induced || 1 0.98 1.04 0.03 0.06 1.36 1.54 0.04 0.42 -0.36 1.34 0.58 -0.49 0.09 0.21 0.21 -0.24
4933 || orf19.7552 || || || Putative U3-containing small subunit processome complex protein; Hap43-induced gene; repressed in core stress response; Spider biofilm induced || 1 1.37 1.24 0.23 0.01 1.54 1.94 0.34 0.44 -0.56 1.16 0.20 -0.56 -0.01 0.14 0.37 -0.31
4934 || orf19.809 || || || Ortholog(s) have role in maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) and nucleolus, preribosome localization || 1 1.34 1.17 0.44 -0.15 1.59 2.10 0.26 0.52 -0.76 1.11 0.59 -0.90 0.17 0.41 0.32 -0.19
4935 || orf19.7552 || || || Putative U3-containing small subunit processome complex protein; Hap43-induced gene; repressed in core stress response; Spider biofilm induced || 1 1.62 1.32 0.40 0.70 1.87 2.09 0.50 0.47 -0.62 1.11 0.20 -1.11 0.41 -0.24 0.52 -0.61
4936 || orf19.2504 || BMS1 || || Putative GTPase; Hap43-induced gene; mutation confers resistance to 5-fluorocytosine (5-FC); flucytosine induced; repressed by prostaglandins; Spider biofilm induced || 1 1.21 1.18 0.84 0.68 1.52 1.97 0.71 0.44 -0.33 1.10 0.22 -0.76 0.16 -0.17 0.46 -0.20
4937 || orf19.7107 || || || Ortholog(s) have role in ribosomal large subunit biogenesis and cytoplasm, nucleus, ribosome localization || 1 1.55 1.60 0.96 0.65 1.78 2.13 0.27 1.04 -0.58 1.48 0.00 -0.98 0.50 0.74 0.54 0.31
4938 || orf19.6766 || NOP13 || || Ortholog of S. cerevisiae Nop13; a nucleolar protein found in preribosomal complexes; Hap43-induced gene; rat catheter biofilm induced || 1 1.29 1.41 0.26 0.29 1.09 1.75 0.46 0.36 -1.07 1.25 0.12 -1.26 0.27 0.49 0.01 0.09
4939 || orf19.2667 || RPF1 || || Putative nucleolar protein with a predicted role in the assembly and export of the large ribosomal subunit; essential for growth; rat catheter and Spider biofilm induced || 1 0.99 0.85 0.47 0.34 0.85 1.25 0.19 -0.10 -0.31 0.63 0.23 -0.58 0.36 -0.02 -0.19 -0.03
4940 || orf19.4760 || || || Putative protein-histidine N-methyltransferase; Spider biofilm induced || 1 0.50 0.65 0.32 0.18 1.21 1.18 0.19 0.01 -0.37 0.75 0.14 -0.83 0.70 0.17 0.13 -0.66
4941 || orf19.2712 || HCA4 || || Putative role in regulation of cell wall biogenesis; Hap43p-induced gene; possibly an essential gene, disruptants not obtained by UAU1 method; flow model and rat catheter biofilm induced || 1 0.82 0.95 0.25 0.10 1.72 1.77 0.53 0.24 -0.43 1.36 0.18 -0.94 0.63 0.16 0.10 -0.79
4942 || orf19.1708 || || || Protein of unknown function; Spider biofilm induced || 1 1.20 1.52 0.57 0.53 2.39 2.41 1.01 0.29 -0.72 1.40 0.06 -0.98 1.20 0.63 0.44 -1.04
4943 || orf19.6862 || || || Hap43-induced gene; mutation confers hypersensitivity to 5-fluorocytosine (5-FC), 5-fluorouracil (5-FU), and tubercidin (7-deazaadenosine) || 1 0.75 0.78 -0.22 0.08 1.50 1.89 0.66 -0.08 -0.59 1.43 -0.02 -0.50 0.81 0.26 0.39 -1.05
4944 || orf19.6862 || || || Hap43-induced gene; mutation confers hypersensitivity to 5-fluorocytosine (5-FC), 5-fluorouracil (5-FU), and tubercidin (7-deazaadenosine) || 1 0.33 0.28 0.23 0.06 0.93 1.55 0.20 -0.00 -0.17 1.09 -0.10 -0.52 0.62 0.32 0.13 -0.47
4945 || orf19.2712 || HCA4 || || Putative role in regulation of cell wall biogenesis; Hap43p-induced gene; possibly an essential gene, disruptants not obtained by UAU1 method; flow model and rat catheter biofilm induced || 1 0.57 0.78 0.50 0.20 1.57 2.41 0.25 0.10 -0.32 1.55 0.37 -0.64 0.54 0.51 0.20 -0.54
4946 || orf19.2712 || HCA4 || || Putative role in regulation of cell wall biogenesis; Hap43p-induced gene; possibly an essential gene, disruptants not obtained by UAU1 method; flow model and rat catheter biofilm induced || 1 0.90 0.51 0.39 0.39 1.32 1.93 0.17 -0.05 -0.54 1.45 0.31 -0.84 0.25 0.06 0.30 -0.41
4947 || orf19.7197 || || || Putative intranuclear transport and DNA replication mediator; heterozygous null mutant exhibits resistance to parnafungin in the C. albicans fitness test; Spider biofilm induced || 1 0.61 0.66 0.27 0.31 0.74 1.37 -0.02 0.12 -0.39 0.74 -0.15 -0.38 0.32 0.03 0.02 -0.61
4948 || orf19.475 || || || Putative rRNA processing protein; rat catheter biofilm induced || 1 0.85 0.85 0.37 0.14 0.88 1.74 0.44 -0.20 -0.24 1.10 -0.20 -0.49 0.28 0.69 0.00 -0.70
4949 || orf19.2314 || || || Protein with a role in nucleolar integrity and processing of pre-rRNA; mutation confers hypersensitivity to 5-fluorocytosine (5-FC), 5-fluorouracil (5-FU), and tubercidin (7-deazaadenosine); Hap43-induced; Spider biofilm induced || 1 1.25 1.18 0.94 0.73 1.94 2.12 0.55 -0.01 -0.71 0.62 0.14 -1.29 0.72 0.19 0.53 -1.66
4950 || orf19.2504 || BMS1 || || Putative GTPase; Hap43-induced gene; mutation confers resistance to 5-fluorocytosine (5-FC); flucytosine induced; repressed by prostaglandins; Spider biofilm induced || 1 1.00 0.96 0.56 0.34 1.42 1.74 0.09 0.13 -0.84 0.47 0.16 -0.97 1.15 -0.31 -0.04 -0.55
4951 || orf19.5010 || DIM1 || || Putative 18S rRNA dimethylase; predicted role in rRNA modification and processing; Hap43-induced; likely to be essential for growth based on insertional mutagenesis strategy; F-12/CO2 early biofilm induced || 1 0.87 0.52 0.76 0.47 0.81 1.34 0.39 0.14 -0.47 0.94 -0.35 -0.82 0.18 -0.45 0.33 -0.45
4952 || orf19.6886 || || || Ortholog(s) have rRNA binding activity, role in maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA), ribosomal large subunit export from nucleus and nucleolus localization || 1 0.72 1.09 1.00 0.76 0.89 1.82 0.23 0.07 -0.08 1.02 -0.31 -0.63 0.47 -0.14 -0.30 -0.71
4953 || orf19.2314 || || || Protein with a role in nucleolar integrity and processing of pre-rRNA; mutation confers hypersensitivity to 5-fluorocytosine (5-FC), 5-fluorouracil (5-FU), and tubercidin (7-deazaadenosine); Hap43-induced; Spider biofilm induced || 1 0.76 0.48 0.74 1.03 1.12 1.42 0.05 0.26 -0.49 0.83 -0.06 -0.20 0.24 0.04 0.19 -0.33
4954 || orf19.6175 || || || Putative 35S rRNA processing protein; Hap43-induced; repressed by prostaglandins; Spider biofilm induced || 1 0.70 0.79 0.11 0.47 1.22 1.74 -0.17 -0.45 -0.42 0.99 -0.05 -0.34 -0.14 0.05 -1.02
4955 || orf19.4143 || FYV5 || || Protein with a predicted role maturation of 18S rRNA; rat catheter biofilm induced || 1 1.88 1.84 -0.18 1.19 2.33 2.33 0.75 -0.14 -1.08 1.43 1.58 1.31 1.27
4956 || orf19.3287 || BUD22 || || Protein with a predicted role in 18S rRNA maturation and small ribosomal subunit biogenesis; repressed in core stress response; repressed by prostaglandins || 1 0.98 1.40 0.35 0.45 1.63 2.18 0.82 -0.31 -0.50 0.58 0.66 -0.58 1.80 0.36 0.82 -1.40
4957 || orf19.7050 || NOP15 || || Nucleolar ribosome biogenesis factor; hyphal-induced expression; Hap43-induced; rat catheter biofilm induced || 1 0.85 0.72 0.13 0.03 1.11 1.17 0.69 0.22 -0.60 0.93 0.53 -1.28 1.39 -0.18 0.22 -1.15
4958 || orf19.2917 || || || Putative GTPase; heterozygous null mutant exhibits resistance to parnafungin in the C. albicans fitness test; Hap43p-induced gene || 1 0.03 0.46 0.61 0.61 0.40 0.99 0.15 -0.17 -0.05 1.11 -0.05 -0.66 0.80 -0.12 -0.35 -0.40
4959 || orf19.920 || RMT2 || || Minor protein arginine methyltransferases (PRMT) involved in methylation of arginine residues || 1 0.02 0.50 0.43 0.09 0.50 0.99 -0.17 0.00 0.09 0.75 0.04 -0.54 0.22 -0.13 -0.35 -0.52
4960 || orf19.76 || SPB1 || || Putative AdoMet-dependent methyltransferase; Hap43-induced; repressed by prostaglandins; possibly essential gene, disruptants not obtained by UAU1 method; Spider biofilm induced || 1 0.18 0.26 0.07 0.12 0.57 0.68 -0.15 0.27 -0.03 0.79 0.04 -0.45 0.22 -0.05 -0.02 -0.49
4961 || orf19.563 || RRP15 || || Putative nucleolar protein; constituent of pre-60S ribosomal particles; Hap43-induced; repressed by prostaglandins || 1 0.18 0.67 0.56 0.38 0.65 1.43 0.31 -0.00 0.06 1.30 -0.20 -0.97 0.52 0.26 -0.33 -0.91
4962 || orf19.6955 || HBR3 || || Essential protein; regulated by hemoglobin; S. cerevisiae ortholog is essential; Hap43p-induced gene || 1 0.22 0.73 0.45 0.33 1.08 1.38 0.26 0.24 0.27 1.70 0.21 -0.80 0.93 0.45 0.03 -0.78
4963 || orf19.1388 || || || Putative 66S pre-ribosomal particle component; Hap43-induced; F-12/CO2 early biofilm induced || 1 0.70 0.95 0.41 0.59 1.01 1.65 0.71 0.43 0.38 1.60 0.42 -0.74 0.65 0.46 -0.23 -1.07
4964 || orf19.4793 || || || Putative ribosome-associated protein; ortholog of S. cerevisiae Tma16; Hap43-induced gene; Spider biofilm induced || 1 0.53 0.74 0.16 0.53 0.52 1.74 0.34 -0.01 -0.30 1.99 -0.30 -0.73 0.54 0.50 -0.43 -0.33
4965 || orf19.813 || || || Protein of unknown function; mutants are viable; Hap43-induced gene; oxidative stress-induced via Cap1; rat catheter and Spider biofilm induced || 1 1.20 1.00 -0.16 -0.69 1.32 0.91 0.51 0.53 -0.63 1.09 -0.77 -1.85 0.17 0.65 -0.32 -1.61
4966 || orf19.813 || || || Protein of unknown function; mutants are viable; Hap43-induced gene; oxidative stress-induced via Cap1; rat catheter and Spider biofilm induced || 1 0.86 1.15 -0.36 -0.41 1.49 1.36 0.65 1.03 -0.29 1.29 -0.43 -1.57 0.16 0.78 -0.22 -1.27
4967 || orf19.5550 || MRT4 || || Putative mRNA turnover protein; Hap43-induced; mutation confers hypersensitivity to tubercidin (7-deazaadenosine); rat catheter biofilm induced || 1 0.67 0.86 -0.18 -0.22 0.87 0.58 0.16 0.65 -0.65 0.89 0.40 -0.50 0.44 0.56 -0.35 -0.76
4968 || orf19.3867 || RPL7 || || Ribosomal protein L7; repressed upon phagocytosis by murine macrophages; Hap43-induced; rat catheter and Spider biofilm induced || 1 0.90 0.85 -0.29 -0.41 0.64 0.78 0.40 0.00 -1.28 0.90 0.20 -0.77 0.01 0.04 -0.56 -0.60
4969 || orf19.5232 || CSI2 || || Putative 66S pre-ribosomal particle component; Hap43-induced; essential for growth; transposon mutation affects filamentous growth; Spider biofilm induced || 1 0.51 0.60 -0.31 -0.59 0.55 0.66 0.54 0.38 -1.01 1.12 0.55 -0.88 0.46 0.25 -0.07 -0.20
4970 || orf19.2319 || || || Putative nucleolar protein with a predicted role in pre-rRNA processing; Hap43-induced gene; repressed in core stress response || 1 0.80 0.95 -0.43 -0.30 1.42 1.44 0.83 0.48 -0.94 1.09 0.82 -0.59 0.75 -0.16 0.33 -0.34
4971 || orf19.1091 || NOP8 || || Ortholog of S. cereviiae Nop8; has a role in ribosomal large subunit biogenesis; rat catheter and Spider biofilm induced || 1 0.87 1.06 -0.84 -0.55 1.50 1.54 0.82 -0.03 -0.41 1.18 0.36 -0.99 0.75 -0.14 1.00 -1.63
4972 || orf19.124 || CIC1 || || Putative proteasome-interacting protein; rat catheter biofilm induced || 1 1.58 1.52 -1.42 -0.03 1.57 1.07 0.76 0.26 -1.11 0.96 0.70 -1.54 0.67 -0.30 0.40 -1.09
4973 || orf19.3867 || RPL7 || || Ribosomal protein L7; repressed upon phagocytosis by murine macrophages; Hap43-induced; rat catheter and Spider biofilm induced || 1 1.11 1.13 -0.61 -0.50 1.17 0.51 0.67 0.31 -1.33 0.81 0.56 -1.07 0.43 -0.07 -0.24 -0.70
4974 || orf19.7050 || NOP15 || || Nucleolar ribosome biogenesis factor; hyphal-induced expression; Hap43-induced; rat catheter biofilm induced || 1 0.64 1.11 -0.49 -0.85 1.43 0.81 0.77 0.05 -0.65 1.36 0.05 -1.34 0.92 -0.10 0.14 -0.75
4975 || orf19.7050 || NOP15 || || Nucleolar ribosome biogenesis factor; hyphal-induced expression; Hap43-induced; rat catheter biofilm induced || 1 0.67 0.62 -0.64 -0.49 0.70 0.46 0.42 0.33 -0.96 1.39 -0.11 -1.35 0.67 -0.18 0.10 -1.04
4976 || orf19.7050 || NOP15 || || Nucleolar ribosome biogenesis factor; hyphal-induced expression; Hap43-induced; rat catheter biofilm induced || 1 0.67 0.73 -0.64 -0.48 1.00 0.58 0.52 -0.01 -1.01 1.29 -0.06 -1.41 0.79 0.17 -0.11 -1.58
4977 || orf19.7050 || NOP15 || || Nucleolar ribosome biogenesis factor; hyphal-induced expression; Hap43-induced; rat catheter biofilm induced || 1 0.60 0.63 -0.67 -0.50 0.86 0.52 0.60 0.23 -0.97 1.38 0.06 -0.92 0.51 0.09 0.18 -1.67
4978 || orf19.2185 || NSA1 || || Putative 66S pre-ribosomal particles conmponent; Hap43-induced; repressed by prostaglandins || 1 0.22 0.47 0.21 -0.13 1.00 1.40 0.47 0.60 -0.27 1.11 0.25 -0.80 0.38 0.50 -0.47 -0.40
4979 || orf19.7422 || || || Ortholog(s) have RNA binding activity and nucleus localization || 1 0.36 0.56 0.04 -0.37 1.14 1.30 0.55 0.71 -0.13 1.15 0.50 -0.69 0.88 0.70 0.04 0.16
4980 || orf19.171 || DBP2 || || Putative DEAD-box family ATP-dependent RNA helicase; flucytosine induced; repressed in core stress response || 1 0.36 0.54 -0.13 0.34 0.47 0.73 -0.09 0.36 -0.29 1.07 -0.15 -1.09 0.02 0.02 -0.08 -0.60
4981 || orf19.2320 || || || Putative serine/threonine-protein kinase; possibly an essential gene, disruptants not obtained by UAU1 method || 1 0.27 0.38 -0.11 0.02 0.69 1.02 -0.12 -0.13 -0.49 1.43 -0.06 -0.27 0.57 -0.20 0.17 -1.44
4982 || orf19.1362 || SMM1 || || Putative dihydrouridine synthase; Hap43-induced gene; rat catheter biofilm induced; Spider biofilm induced || 1 0.18 0.39 0.02 -0.01 1.16 1.80 0.76 -0.71 -0.06 1.11 -0.74 -0.18 1.16 0.96 0.47 -1.44
4983 || orf19.1362 || SMM1 || || Putative dihydrouridine synthase; Hap43-induced gene; rat catheter biofilm induced; Spider biofilm induced || 1 0.25 0.09 -0.09 -0.12 0.88 1.24 0.78 -0.40 -0.32 1.53 -0.64 0.85 0.35 0.64 -1.36
4984 || orf19.4634 || || || Protein required for thiolation of uridine at wobble position of Gln, Lys, and Glu tRNAs; has a role in urmylation; S. cerevisiae ortholog has a role in invasive and pseudohyphal growth || 1 0.20 0.14 0.08 -0.12 1.28 1.55 -0.02 -0.30 -0.47 0.97 -0.25 -0.47 1.02 -0.20 0.79 -0.57
4985 || orf19.2830 || RRP9 || || Ribosomal protein; mutation confers resistance to 5-fluorocytosine (5-FC), 5-fluorouracil (5-FU), and tubercidin (7-deazaadenosine); physically interacts with TAP-tagged Nop1; Hap43-induced; Spider biofilm induced || 1 0.17 0.96 -0.03 -0.40 1.76 1.29 0.21 -0.03 -0.06 1.31 -0.22 -0.28 0.77 0.34 -1.14
4986 || orf19.429 || || || Putative non-canonical poly(A) polymerase; repressed by nitric oxide; Spider biofilm induced || 1 -0.03 0.25 -0.32 -0.50 0.97 0.85 0.01 0.02 -0.06 0.57 -0.01 -0.10 0.31 0.10 0.40 -0.47
4987 || orf19.2449 || || || Putative adhesin-like protein; macrophage-induced gene || 1 1.25 0.65 -0.36 1.06 1.90 -0.04 -0.44 -0.08 1.08 0.08 0.20 0.25 1.27 -0.72
4988 || orf19.2309 || PET127 || || Protein with a predicted role in 5'-end processing of mitochondrial RNAs; ortholog of S. cerevisiae Pet127; Hap43-induced; rat catheter and Spider biofilm induced || 1 0.90 1.01 -0.11 -0.57 1.17 1.29 0.47 0.14 -0.16 1.07 -0.17 -0.07 0.21 0.26 0.84 -0.82
4989 || orf19.2309 || PET127 || || Protein with a predicted role in 5'-end processing of mitochondrial RNAs; ortholog of S. cerevisiae Pet127; Hap43-induced; rat catheter and Spider biofilm induced || 1 0.77 0.55 0.41 -0.49 0.97 1.30 -0.10 -0.23 -0.48 1.18 -0.50 -0.25 0.40 0.40 0.25 -0.33
4990 || orf19.4835 || || || Ortholog(s) have role in endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA and LSU-rRNA), more || 1 0.81 0.81 -0.10 -0.54 1.69 2.38 0.53 -0.09 -0.38 0.63 0.28 -0.36 0.51 0.56 0.04 -0.18
4991 || orf19.154 || || || Putative ortholog of S. cerevisiae Utp30; a U3-containing 90S preribosome complex protein; Hap43-induced; Spider biofilm induced || 1 0.78 0.70 0.37 -0.95 0.96 1.57 0.89 -0.28 -0.82 0.41 0.13 -0.30 0.74 0.42 0.12 -0.17
4992 || orf19.718 || RRN11 || || Putative RNA polymerase I subunit; rat catheter biofilm induced; Spider biofilm induced || 1 0.43 0.23 -0.10 -0.68 0.60 1.23 0.46 -0.21 -0.21 0.69 -0.17 -0.01 0.48 0.40 -0.25 -0.28
4993 || orf19.7361 || || || Ortholog(s) have tRNA-intron endonuclease activity, role in tRNA-type intron splice site recognition and cleavage and mitochondrial outer membrane, tRNA-intron endonuclease complex localization || 1 0.27 0.21 -0.12 -0.44 0.68 0.86 0.54 -0.40 -0.55 0.44 -0.10 0.53 0.01 0.46 -0.09
4994 || orf19.4538 || || || Ortholog(s) have mRNA binding, protein heterodimerization activity, role in mRNA cleavage, mRNA polyadenylation and U2 snRNP, mRNA cleavage factor complex localization || 1 0.77 0.60 0.20 0.06 0.69 0.37 -0.07 0.09 -0.27 0.44 0.23 -0.32 -0.13 0.12 0.43 -0.52
4995 || orf19.7366 || || || Ortholog(s) have S-adenosylmethionine-dependent methyltransferase activity and nucleolus localization || 1 0.61 0.38 0.04 -0.18 0.58 0.58 -0.12 0.04 -0.85 0.06 0.45 -0.32 -0.19 -0.01 0.06 -0.35
4996 || orf19.6230 || || || Ortholog(s) have enzyme regulator activity, pyrophosphatase activity || 1 0.32 0.26 0.12 -0.11 0.72 1.06 0.03 -0.32 -1.05 0.50 0.25 0.12 -0.14 -0.11 0.18 -0.54
4997 || orf19.6230 || || || Ortholog(s) have enzyme regulator activity, pyrophosphatase activity || 1 0.27 0.40 0.16 -0.02 0.49 0.91 -0.12 -0.42 -0.52 0.74 0.36 0.14 -0.31 0.09 0.46 -0.29
4998 || orf19.4092 || || || Trimeric GatFAB AmidoTransferase(AdT) complex subunit; involved in the formation of Q-tRNAQ; repressed by fluphenazine treatment or in an azole-resistant strain that overexpresses CDR1; Spider biofilm induced || 1 -0.24 0.15 0.24 -0.12 0.53 1.10 0.13 -0.40 -0.24 0.93 0.23 0.33 0.06 -0.03 0.02 0.08
4999 || orf19.5566 || || || Ortholog(s) have role in protein lipoylation and mitochondrion localization || 1 -0.18 -0.18 -0.09 -0.17 0.54 1.11 0.12 -0.63 -0.28 0.71 -0.24 0.14 0.25 -0.04 0.14 -0.18
5000 || orf19.7088 || || || Ortholog(s) have single-stranded telomeric DNA binding activity, role in regulation of translational fidelity, telomere maintenance, threonylcarbamoyladenosine metabolic process and cytosol, nucleus localization || 1 0.18 0.09 0.31 0.12 0.38 1.20 -0.01 -0.28 -0.26 1.26 -0.47 0.04 0.22 0.20 0.22 -0.34
5001 || orf19.4962 || RMP1 || || Ortholog of Rmp1; subunit of RNase MRP subunit that processes pre-rRNA and has a role in cell cycle-regulated degradation of daughter cell-specific mRNAs; rat catheter and Spider biofilm induced || 1 -0.02 0.19 0.31 0.19 0.60 1.55 -0.33 -0.32 -0.27 0.93 -0.16 0.19 -0.06 -0.18 0.00 -0.38
5002 || orf19.6686 || ENP2 || || Putative nucleolar protein; essential; heterozygous mutation confers resistance to 5-fluorocytosine (5-FC), 5-fluorouracil (5-FU), and tubercidin (7-deazaadenosine); Hap43-induced; Spider biofilm induced || 1 0.25 0.37 0.29 -0.19 0.95 2.30 0.05 -0.48 -0.48 1.24 -0.03 -0.31 -0.11 0.23 -0.17 0.04
5003 || orf19.2362 || || || Putative 90S preribosome component; Hap43p-induced gene; possibly an essential gene, disruptants not obtained by UAU1 method || 1 0.17 0.27 0.68 0.12 0.41 1.99 -0.00 -0.56 -0.67 0.92 -0.37 -0.48 0.11 -0.08 -0.25 -0.58
5004 || orf19.2404 || || || Ortholog(s) have RNA binding, ribonuclease MRP activity, ribonuclease P activity and role in intronic box C/D snoRNA processing, mRNA cleavage, rRNA processing, tRNA processing || 1 0.28 0.43 0.44 -0.16 0.60 1.33 -0.38 -0.54 -0.35 0.43 -0.12 -0.18 0.03 -0.25 0.06 0.06
5005 || orf19.5567 || POP4 || || Ortholog of S. cerevisiae Pop4; a subunit of both RNase MRP and nuclear RNase P; filament induced; regulated by Nrg1, Tup1; likely essential, based on UAU1 strategy; rat catheter and Spider biofilm induced || 1 0.17 0.40 0.46 -0.06 0.52 0.96 0.01 -0.09 -0.27 0.51 0.13 -0.24 0.59 -0.05 0.22 -0.12
5006 || orf19.3609 || UTP15 || || Small subunit (SSU) processome component; mutation confers resistance to 5-fluorocytosine (5-FC); physically interacts with TAP-tagged Nop1p || 1 0.42 0.49 0.62 0.12 0.45 1.13 0.43 -0.10 -0.21 0.52 -0.17 -0.37 0.54 -0.01 0.03 -0.02
5007 || orf19.154 || || || Putative ortholog of S. cerevisiae Utp30; a U3-containing 90S preribosome complex protein; Hap43-induced; Spider biofilm induced || 1 0.51 0.56 0.95 0.13 0.69 1.76 0.47 -0.46 -0.44 0.28 0.15 0.19 0.72 0.44 -0.18 -0.30
5008 || orf19.154 || || || Putative ortholog of S. cerevisiae Utp30; a U3-containing 90S preribosome complex protein; Hap43-induced; Spider biofilm induced || 1 0.68 0.56 1.25 0.30 0.94 1.91 0.89 -0.20 -0.04 0.65 0.09 0.44 0.84 0.23 0.25 0.13
5009 || orf19.154 || || || Putative ortholog of S. cerevisiae Utp30; a U3-containing 90S preribosome complex protein; Hap43-induced; Spider biofilm induced || 1 0.11 0.06 0.96 0.55 0.90 1.58 0.55 -0.28 -0.07 0.48 0.23 0.13 1.11 0.56 0.02 -0.12
5010 || orf19.3304 || || || Exosome non-catalytic core component; involved in 3'-5' RNA processing and degradation in the nucleus and cytoplasm; Spider biofilm induced || 1 0.08 0.25 0.46 0.27 1.07 1.67 0.24 -0.17 -0.20 0.84 0.35 -0.01 0.50 0.32 -0.25 -0.32
5011 || orf19.4191 || RLP24 || || Putative ribosomal protein; Hap43-induced; essential gene; heterozygous mutation confers hypersensitivity to 5-fluorocytosine (5-FC), 5-fluorouracil (5-FU), and tubercidin (7-deazaadenosine); Spider biofilm induced || 1 0.13 0.09 0.25 0.27 0.51 1.55 -0.01 0.05 -0.26 1.31 0.18 -0.44 0.31 0.61 -0.04 -0.17
5012 || orf19.1609 || || || Ortholog(s) have role in endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) and mitotic spindle pole body, nucleolus localization || 1 0.30 0.24 0.54 0.27 1.03 2.04 0.20 0.08 -0.01 2.04 0.00 0.12 0.41 0.99 -0.31 0.40
5013 || orf19.5299 || ECM1 || || Putative pre-ribosomal factor; decreased mRNA abundance observed in cyr1 homozygous mutant hyphae; induced by heavy metal (cadmium) stress; Hog1p regulated || 1 0.44 0.77 1.09 0.56 1.40 2.39 0.48 0.22 0.57 1.91 0.09 -0.10 0.71 1.05 -0.52 0.25
5014 || orf19.5299 || ECM1 || || Putative pre-ribosomal factor; decreased mRNA abundance observed in cyr1 homozygous mutant hyphae; induced by heavy metal (cadmium) stress; Hog1p regulated || 1 0.32 0.24 1.18 0.72 0.53 2.23 0.16 0.12 0.20 1.49 -0.13 -0.35 0.03 0.93 -0.22 -0.24
5015 || orf19.5299 || ECM1 || || Putative pre-ribosomal factor; decreased mRNA abundance observed in cyr1 homozygous mutant hyphae; induced by heavy metal (cadmium) stress; Hog1p regulated || 1 0.66 0.70 0.90 0.84 0.81 2.37 -0.03 0.28 0.17 1.78 0.43 -0.06 -0.19 0.88 0.22 0.16
5016 || orf19.2712 || HCA4 || || Putative role in regulation of cell wall biogenesis; Hap43p-induced gene; possibly an essential gene, disruptants not obtained by UAU1 method; flow model and rat catheter biofilm induced || 1 0.73 0.41 0.47 0.32 1.34 1.99 -0.14 0.35 -0.19 1.48 -0.12 -0.32 0.03 0.53 0.08 -0.01
5017 || orf19.58 || RRP6 || || Putative nuclear exosome exonuclease component; Hap43p-induced gene; mutation confers hypersensitivity to 5-fluorocytosine (5-FC), 5-fluorouracil (5-FU), and tubercidin (7-deazaadenosine) || 1 0.25 0.34 0.72 0.40 0.80 1.98 -0.02 0.08 0.03 0.84 0.47 -0.02 0.26 0.69 0.06 0.67
5018 || orf19.2167 || || || Ortholog(s) have role in ribosomal large subunit biogenesis, ribosomal small subunit biogenesis and cytosolic large ribosomal subunit, nucleolus localization || 1 0.58 0.39 1.13 0.88 0.96 1.84 0.28 0.24 0.28 1.68 -0.08 0.34 0.54 0.36 0.53 -0.07
5019 || orf19.3609 || UTP15 || || Small subunit (SSU) processome component; mutation confers resistance to 5-fluorocytosine (5-FC); physically interacts with TAP-tagged Nop1p || 1 0.23 0.20 0.65 0.59 0.59 1.15 0.13 0.31 0.41 0.60 0.08 0.07 0.35 0.31 0.14 0.41
5020 || orf19.6369 || RIO2 || || Putative serine kinase with a predicted role in the processing of the 20S pre-rRNA into mature 18S rRNA; null mutants are hypersensitive to caspofungin || 1 0.36 0.45 0.57 0.69 0.75 1.18 0.62 0.46 0.49 1.31 0.32 0.11 0.68 0.55 -0.09 0.33
5021 || orf19.4895 || || || Ortholog of C. dubliniensis CD36 : Cd36_09650, C. parapsilosis CDC317 : CPAR2_805060, Candida tenuis NRRL Y-1498 : CANTEDRAFT_95780 and Debaryomyces hansenii CBS767 : DEHA2B12320g || 1 0.33 0.41 0.36 0.17 0.95 1.47 0.43 0.13 0.60 1.00 -0.14 0.15 0.47 0.68 0.17 -0.31
5022 || orf19.1772 || || || Ortholog(s) have mitochondrion localization || 1 0.46 0.85 0.34 -0.15 0.98 2.27 -0.04 0.12 0.32 1.24 0.17 0.05 0.15 0.59 0.30 -0.28
5023 || orf19.2676 || || || Predicted hexameric RecA-like ATPase Elp456 Elongator subcomplex subunit; required for modification of wobble nucleosides in tRNA; Spider biofilm induced || 1 0.37 0.08 0.28 0.39 0.46 1.09 -0.12 -0.02 -0.24 0.35 0.06 0.41 -0.02 -0.15 0.03 0.01
5024 || orf19.7464 || || || Putative subtilisin-family protease; mutation confers hypersensitivity to toxic ergosterol analog || 1 0.67 0.18 0.22 0.70 -0.05 0.39 -0.69 0.48 0.26 -0.09 -0.07 0.31 0.30
5025 || orf19.4029 || || || Ortholog(s) have role in ribosomal large subunit assembly and cytosolic ribosome, nucleus localization || 1 0.55 0.38 0.30 0.22 0.48 0.68 0.17 -0.00 -0.33 0.54 0.21 -0.25 0.25 -0.19 0.10 0.41
5026 || orf19.2385 || KTI12 || || Protein similar to S. cerevisiae Kti12p, which associates with Elongator complex; has a role in resistance to killer toxin; predicted Kex2p substrate; Hap43p-induced gene || 1 0.28 0.09 0.11 -0.06 0.48 0.89 0.06 0.11 -0.56 0.72 -0.41 0.12 -0.11 -0.20 0.31 -0.02
5027 || orf19.6759 || || || Protein of unknown function || 1 0.14 0.23 0.33 0.17 0.65 0.19 0.00 0.01 0.10 0.22 -0.58 -0.19 0.16 0.37 0.15 -0.44
5028 || orf19.4600 || || || Protein of unknown function; possible mitochondrial protein; Spider biofilm induced || 1 0.80 0.59 0.40 0.29 2.02 0.56 0.33 0.03 -0.15 0.49 -0.31 -0.34 0.20 0.20 0.23 -0.65
5029 || orf19.5962 || HGT4 || || Glucose and galactose sensor; fermentation, filamentation, virulence roles; 20-member glucose transporter family; extended C terminus; high-glucose repressed; macrophage induced; flow model biofilm repressed; Spider biofilm induced || 1 0.25 0.07 0.06 0.18 0.76 -0.06 -0.20 -0.22 -0.11 0.19 -0.13 -0.16 0.06 -0.14 0.29 -0.29
5030 || orf19.2000 || || || Ortholog(s) have DNA helicase activity, role in DNA replication initiation, donor selection, interstrand cross-link repair, mitotic sister chromatid cohesion, negative regulation of DNA recombination and cytosol, nucleus localization || 1 0.38 -0.03 -0.39 -0.53 0.95 -0.24 -0.09 0.44 0.12 0.77 -0.02 -0.56 0.21 -0.20 -0.49 -0.54
5031 || orf19.119 || || || Ortholog(s) have protein C-terminal S-isoprenylcysteine carboxyl O-methyltransferase activity || 1 -0.00 0.23 -0.61 -0.42 0.99 -0.62 0.29 0.12 -0.27 0.38 0.44 0.03 -0.09 0.09 -0.18 -0.39
5032 || orf19.7594 || || || Protein of unknown function; Spider biofilm induced || 1 0.29 0.53 0.11 0.04 0.88 -0.55 0.27 -0.08 -0.47 0.44 0.54 -0.26 -0.18 0.02 -0.37 0.40
5033 || orf19.3181.1 || || || Protein of unknown function; involved in secretion of proteins that lack classical secretory signal sequences; Spider biofilm induced || 1 0.51 0.56 -0.13 -0.03 0.54 -0.27 0.50 0.44 -0.87 0.10 0.49 -0.42 -0.17 -0.11 0.32 -0.41
5034 || orf19.2869 || || || Ortholog of C. dubliniensis CD36 : Cd36_46110, Candida tropicalis MYA-3404 : CTRG_03792 and Candida albicans WO-1 : CAWG_03165 || 1 0.77 0.46 0.24 0.57 -0.30 0.68 0.65 0.77 0.39 -0.41 0.58 -0.64
5035 || orf19.2829 || || || Ortholog(s) have role in protein transport and endoplasmic reticulum, nuclear envelope localization || 1 0.82 0.67 -0.24 0.33 0.76 -0.06 0.21 0.53 -0.62 0.95 0.02 -0.64 0.08 0.46 -0.05 -0.34
5036 || orf19.427 || || || Ortholog(s) have telomeric DNA binding activity and role in chromatin silencing at silent mating-type cassette, chromatin silencing at telomere, single-species biofilm formation on inanimate substrate, telomere capping || 1 0.28 0.34 0.06 0.07 1.19 -0.03 0.07 0.39 -0.06 0.75 0.68 -0.23 -0.52 -0.16 0.20 0.06
5037 || orf19.5100 || MLT1 || || Vacuolar membrane transporter; MRP subfamily of ABC family; may transport organic anions conjugated to glutathione, glucuronate, or sulfate; needed for virulence in mouse peritonitis; Spider biofilm induced; flow model biofilm repressed || 1 0.06 0.25 0.00 0.24 0.36 0.12 -0.01 0.78 0.02 0.37 0.60 -0.01 -0.31 0.14 0.51 0.05
5038 || orf19.4861.1 || || || Protein of unknown function || 1 0.54 0.22 0.36 0.20 -0.03 0.67 -0.11 0.09 -0.14 0.18 -0.22 0.22 -0.25 -0.16
5039 || orf19.2430 || || || Ortholog of Candida albicans WO-1 : CAWG_00792 || 1 0.87 0.97 0.57 0.49 0.35 1.08 0.41 0.28 0.82 -0.29 0.59 0.13 -0.66 0.70 -0.16 -0.12
5040 || orf19.7643 || || || Ortholog(s) have 4-hydroxybenzoate octaprenyltransferase activity, antioxidant activity and role in cellular response to cadmium ion, detoxification of cadmium ion, ubiquinone biosynthetic process || 1 0.00 0.28 0.10 0.16 0.57 0.62 0.03 0.14 0.53 0.07 -0.15 0.01 -0.10 0.31 -0.23 -0.35
5041 || orf19.2472 || || || Ortholog of S. pombe replication termination factor Rtf2; Spider biofilm induced || 1 0.08 0.13 0.24 -0.03 0.44 0.53 -0.06 0.42 0.35 0.33 0.14 0.22 -0.28 0.12 -0.04 -0.15
5042 || orf19.1062 || || || Ortholog of C. dubliniensis CD36 : Cd36_04020, C. parapsilosis CDC317 : CPAR2_107000, Candida tenuis NRRL Y-1498 : CANTEDRAFT_113990 and Pichia stipitis Pignal : PICST_32780 || 1 0.54 0.50 0.21 -0.12 0.22 1.11 0.29 0.67 0.10 0.38 -0.04 0.82 -0.51 0.47 0.69 -0.22
5043 || orf19.5168 || || || Ortholog(s) have role in maturation of SSU-rRNA and cytosol, nucleolus localization || 1 0.39 0.24 0.10 -0.20 0.53 0.61 -0.03 0.19 0.24 0.55 -0.33 -0.03 -0.15 0.08 0.32 0.16
5044 || orf19.7482 || || || Ortholog of C. parapsilosis CDC317 : CPAR2_803740, C. dubliniensis CD36 : Cd36_25640, Lodderomyces elongisporus NRLL YB-4239 : LELG_00467 and Candida orthopsilosis Co 90-125 : CORT_0A03760 || 1 0.73 0.48 -0.25 -0.05 0.59 -0.09 0.15 -0.26 -0.07 -0.39 0.21 0.18
5045 || orf19.4229 || || || Putative polyphosphate phosphatase; role in hydrolysis of diphosphorylated inositol polyphosphates and diadenosine polyphosphates; Spider biofilm induced || 1 0.09 0.16 -0.00 0.17 0.22 0.61 0.08 0.27 0.56 -0.01 0.05 0.27 -0.78 -0.10 0.41 0.24
5046 || orf19.5308 || || || Protein of unknown function; induced by Rgt1 || 1 0.55 0.53 0.53 0.09 0.06 0.82 0.16 0.79 0.34 -0.28 -0.20 -0.09 -0.90 -0.66 0.52 0.50
5047 || orf19.4847 || || || Ortholog of Candida albicans WO-1 : CAWG_00450 || 1 1.27 0.08 0.77 -0.17 0.78 0.61 0.41 0.26 0.27 0.04 -0.50 -1.07 -0.38 0.54
5048 || orf19.6208 || MEF2 || || Putative mitochondrial translation elongation factor; caspofungin induced || 1 -0.44 0.73 0.25 -0.32 1.22 1.13 -0.09 0.41 0.03 0.06 0.28 0.27 -0.14 -0.41 0.47 0.07
5049 || orf19.1735 || || || Ortholog(s) have U2-type spliceosomal complex localization || 1 0.69 0.35 0.28 -0.73 1.73 0.63 0.30 -0.04 1.36 -0.11 0.69 -1.16 0.65 1.07
5050 || orf19.4227 || || || Ortholog of C. parapsilosis CDC317 : CPAR2_100400, C. dubliniensis CD36 : Cd36_52020, Debaryomyces hansenii CBS767 : DEHA2F14278g and Candida orthopsilosis Co 90-125 : CORT_0F00500 || 1 0.97 0.36 -0.34 1.15 0.01 0.58 -0.35 1.36 0.07 0.24 -2.00 0.46 0.45
5051 || orf19.416 || || || Ortholog of C. dubliniensis CD36 : Cd36_05200, C. parapsilosis CDC317 : CPAR2_107660, Candida tenuis NRRL Y-1498 : cten_CGOB_00159 and Debaryomyces hansenii CBS767 : DEHA2E07854g || 1 0.71 0.51 -0.29 0.17 1.08 1.96 -0.00 0.74 -0.55 0.04 -0.44 -0.33 -0.24 0.80 0.33
5052 || orf19.6280 || || || Dubious open reading frame || 1 1.11 0.40 -1.12 1.42 1.97 0.30 2.08 1.00 0.20 0.58 0.77 0.28
5053 || orf19.259 || || || Protein with a predicted role in 60S ribosomal subunit assembly; flow model biofilm induced || 1 1.06 0.98 -0.34 1.14 2.07 0.29 0.90 0.71 0.68 0.75 0.82 -1.26 1.29 0.47
5054 || orf19.5464 || || || Protein of unknown function || 1 1.29 0.48 -0.06 0.48 1.15 0.50 1.45 -1.00 -0.10 0.22 0.90 0.43 1.05 -0.23
5055 || orf19.6918 || || || Protein of unknown function; Hap43-induced gene; Spider biofilm induced || 1 0.49 0.49 -0.47 -0.27 0.91 0.74 0.38 -0.02 -0.29 0.62 0.79 0.29 0.44 -1.01 0.82 -0.65
5056 || orf19.5920 || || || Ortholog of C. dubliniensis CD36 : Cd36_84570, C. parapsilosis CDC317 : CPAR2_404420, Candida tenuis NRRL Y-1498 : CANTEDRAFT_115339 and Debaryomyces hansenii CBS767 : DEHA2G13618g || 1 0.70 0.69 -0.13 -0.68 1.10 0.59 0.60 0.59 0.75 0.20 -0.31 -0.34 -0.08 -0.75 0.73 -0.76
5057 || orf19.1770 || CYC1 || || Cytochrome c; complements defects of S. cerevisiae cyc1 cyc7 double mutant; induced in high iron; alkaline repressed; repressed by nitric oxide; Hap43-dependent repression in low iron; regulated by Sef1, Sfu1 || 1 0.82 0.75 0.12 -0.06 0.91 1.26 0.84 0.96 1.00 0.58 0.54 0.56 -0.90 -0.97 0.31 -0.42
5058 || orf19.1770 || CYC1 || || Cytochrome c; complements defects of S. cerevisiae cyc1 cyc7 double mutant; induced in high iron; alkaline repressed; repressed by nitric oxide; Hap43-dependent repression in low iron; regulated by Sef1, Sfu1 || 1 0.40 0.47 -0.57 -0.81 0.55 1.06 0.41 0.43 0.42 0.14 0.20 0.34 -1.10 -1.12 0.10 -0.30
5059 || orf19.2624 || || || Protein of unknown function; downregulated by fluphenazine treatment or in an azole-resistant strain that overexpresses CDR1 and CDR2 || 1 0.20 0.76 -0.50 -0.30 0.62 0.31 0.01 0.71 -0.49 0.23 -0.12 1.12 -0.80 0.14 -0.45
5060 || orf19.4869 || SFU1 || || GATA-type transcription factor; regulator of iron-responsive genes; represses iron utilization genes if iron is present; Hap43-repressed; promotes gastrointestinal commensalism in mice; Spider biofilm induced || 1 0.32 0.62 -0.37 -0.86 1.45 0.14 -0.12 -0.27 -0.61 -0.32 0.37 1.14 -1.05 -0.78 0.66 -0.26
5061 || orf19.4869 || SFU1 || || GATA-type transcription factor; regulator of iron-responsive genes; represses iron utilization genes if iron is present; Hap43-repressed; promotes gastrointestinal commensalism in mice; Spider biofilm induced || 1 0.46 0.53 -0.19 -0.60 1.56 0.33 0.10 -0.01 -0.50 -0.27 0.45 1.13 -0.62 -0.88 0.74 -0.24
5062 || orf19.4761 || HST1 || || Putative histone deacetylase, involved in regulation of white-opaque switching || 1 0.25 0.30 -0.49 0.01 0.41 0.21 -0.01 0.17 -0.39 -0.00 0.42 -0.12 0.03 -0.46 -0.05 0.14
5063 || orf19.3220 || || || Putative rRNA processing protein; Spider biofilm induced || 1 1.08 1.02 0.19 0.26 0.72 0.77 0.47 -0.51 -1.00 0.13 -0.47 -1.25 0.31 -0.58 -0.49 -1.83
5064 || orf19.4963 || || || Ortholog(s) have role in ER-associated ubiquitin-dependent protein catabolic process and cytoplasm, nucleolus localization || 1 0.24 -0.00 -0.59 -0.25 0.30 0.32 -0.30 -0.20 -0.82 0.94 0.36 -0.17 0.24 -0.01 0.50 -0.87
5065 || orf19.2492 || STE3 || || Protein similar to S. cerevisiae Ste3p, the receptor for a-factor mating pheromone; alpha mating-type-specific transcription || 1 -0.28 0.10 -0.60 -0.57 -0.10 0.15 -0.44 -0.49 1.70 0.30 -0.59 -0.24 1.25 -0.27
5066 || orf19.4125 || PZF1 || || C2H2 transcription factor; Hap43-induced; rat catheter and Spider biofilm induced || 1 -0.62 -0.54 -1.26 -1.25 0.53 0.04 0.53 0.13 -0.37 0.49 0.25 -0.62 0.21 0.77 -1.26 -0.89
5067 || orf19.5987 || || || Ortholog(s) have tRNA (guanine-N2-)-methyltransferase activity, role in tRNA methylation and cytosol, nucleus, tRNA (m2G10) methyltransferase complex localization || 1 -0.08 -0.10 -0.20 -0.34 0.18 0.63 0.38 -0.15 -0.43 0.54 -0.03 -0.73 0.31 -0.12 -0.16 -0.77
5068 || orf19.2859 || SRP40 || || Putative chaperone of small nucleolar ribonucleoprotein particles; macrophage/pseudohyphal-induced; rat catheter biofilm induced || 1 0.23 0.47 -1.02 -0.54 0.05 0.52 0.87 0.10 -0.75 0.98 0.18 -1.03 0.98 0.70 0.06 -1.16
5069 || orf19.2859 || SRP40 || || Putative chaperone of small nucleolar ribonucleoprotein particles; macrophage/pseudohyphal-induced; rat catheter biofilm induced || 1 0.20 0.49 -0.43 -0.14 -0.44 0.82 0.43 -0.22 -0.65 0.93 -0.46 -0.82 0.71 0.49 -0.46 -1.34
5070 || orf19.172 || RPC19 || || Putative RNA polymerases I and III subunit AC19; Hap43-induced; rat catheter biofilm induced || 1 0.34 0.45 -1.05 -0.84 -0.38 -0.12 0.49 0.13 -1.35 1.17 -0.05 -1.08 0.56 -0.06 -0.34 -1.42
5071 || orf19.2859 || SRP40 || || Putative chaperone of small nucleolar ribonucleoprotein particles; macrophage/pseudohyphal-induced; rat catheter biofilm induced || 1 -0.06 0.06 -0.94 -0.57 -0.46 0.18 0.67 -0.39 -1.11 0.91 -0.48 -1.48 0.61 0.22 -0.57 -2.12
5072 || orf19.2538 || PTC2 || || Protein phosphatase of the Type 2C-related family (serine/threonine-specific) with a potential role in DNA damage checkpoint control; localizes to both cytoplasm and mitochondria; mutant shows virulence defect || 1 -0.14 -0.17 -0.27 -0.27 -0.44 -0.16 0.11 -0.11 -0.74 0.34 -0.16 -0.59 0.24 -0.02 -0.16 -0.77
5073 || orf19.6340 || || || Ortholog(s) have RNA polymerase I activity, RNA polymerase II activity, RNA polymerase III activity, RNA-directed RNA polymerase activity || 1 0.05 -0.07 -0.59 -0.63 -0.10 -0.24 -0.17 -0.02 -0.87 0.30 0.34 -0.35 0.08 0.09 -0.15 -0.51
5074 || orf19.5232 || CSI2 || || Putative 66S pre-ribosomal particle component; Hap43-induced; essential for growth; transposon mutation affects filamentous growth; Spider biofilm induced || 1 -0.07 0.02 -1.14 -1.13 0.08 0.35 -0.10 0.03 -1.57 0.96 0.27 -1.40 0.02 0.03 -0.55 -0.86
5075 || orf19.4640 || PWP1 || || Putative rRNA processing protein; Hap43-induced; repressed in core stress response || 1 -0.03 0.18 -0.94 -0.66 0.25 0.26 0.23 0.50 -0.68 1.49 -0.07 -1.37 0.16 0.76 -0.79 -0.81
5076 || orf19.706 || NMD3 || || Putative nonsense-mediated mRNA decay protein; repressed in core stress response; repressed by prostaglandins || 1 -0.01 0.17 -0.74 -0.96 0.31 0.71 0.08 0.20 -0.36 1.00 -0.32 -0.70 0.06 0.24 -0.18 -0.25
5077 || orf19.5550 || MRT4 || || Putative mRNA turnover protein; Hap43-induced; mutation confers hypersensitivity to tubercidin (7-deazaadenosine); rat catheter biofilm induced || 1 0.88 0.77 -0.45 -0.63 0.20 0.29 0.44 1.16 -0.89 1.02 -0.03 -0.67 0.03 0.50 -1.43 -1.09
5078 || orf19.443 || || || Ortholog(s) have DNA-directed RNA polymerase activity, RNA polymerase III activity and role in tRNA transcription from RNA polymerase III promoter, transcription initiation from RNA polymerase III promoter || 1 0.16 0.37 0.03 -0.25 0.31 0.34 0.19 0.58 -0.31 0.51 0.69 -0.65 0.15 0.37 -0.49 -0.43
5079 || orf19.3704 || || || Ortholog(s) have role in maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA), maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) || 1 -0.18 0.03 0.08 -0.19 0.25 0.65 -0.09 -0.40 -0.01 0.43 -0.43 -0.83 0.05 0.48 -0.75 -1.41
5080 || orf19.1529 || || || Protein of unknown function; macrophage-induced gene || 1 -0.22 -0.02 0.23 -0.20 0.22 0.27 -0.67 -0.72 0.37 0.31 -0.50 -1.23 0.19 0.09 -0.49 -0.73
5081 || orf19.7215 || || || Nucleolar protein; component of the small subunit processome containing the U3 snoRNA; involved in pre-18S rRNA processing; flow model biofilm repressed || 1 -0.12 0.08 0.38 -0.02 0.57 0.51 -0.06 0.01 -0.02 0.23 -0.04 -0.28 -0.22 -0.03 -0.34 0.14
5082 || orf19.3091 || || || Protein of unknown function; repressed during core stress response || 1 -0.08 0.07 0.36 0.19 0.34 0.71 -0.40 -0.28 0.23 0.17 -0.13 -0.35 0.35 0.09 -0.53 -0.13
5083 || orf19.1886 || RCL1 || || Putative U3-containing 90S preribosome processome complex subunit; Hap43-induced; essential; S. cerevisiae ortholog is essential; represses in core stress response; || 1 -0.09 -0.15 0.53 0.20 0.21 0.83 -0.06 -0.16 -0.30 0.42 -0.13 -0.37 0.00 -0.41 -0.39 -0.17
5084 || orf19.1902 || NOC4 || || Putative nucleolar protein; Hap43-induced; mutation confers resistance to 5-fluorocytosine (5-FC), 5-fluorouracil (5-FU), and tubercidin (7-deazaadenosine); Spider biofilm induced || 1 -0.05 0.36 0.75 0.20 0.14 1.11 -0.18 -0.17 -0.14 1.11 -0.47 -0.65 -0.08 -0.10 -1.18 -0.16
5085 || orf19.5608 || || || RNA polymerase III subunit; Spider biofilm induced || 1 -0.13 0.06 0.72 0.35 0.07 0.82 -0.21 -0.51 0.17 1.05 -0.68 -0.45 0.29 0.08 -0.63 -0.44
5086 || orf19.939 || NAM7 || || Putative role in nonsense-mediated mRNA decay; similar to S. cerevisiae Nam7p; gene induced by ciclopirox olamine treatment || 1 -0.01 0.08 0.44 0.32 -0.05 0.33 -0.25 -0.57 -0.23 0.40 -0.44 -0.25 -0.11 -0.26 -0.46 0.11
5087 || orf19.5847 || || || Ortholog(s) have RNA polymerase III activity, role in tRNA transcription from RNA polymerase III promoter and DNA-directed RNA polymerase III complex, cytosol localization || 1 -0.00 0.26 0.03 0.01 0.33 0.77 -0.57 -0.23 -0.22 0.64 -0.09 -0.31 -0.44 -0.26 -0.20 0.03
5088 || orf19.5038 || || || Predicted tRNA (guanine) methyltransferase activity; Spider biofilm induced || 1 0.15 0.07 0.37 0.23 0.10 0.59 -0.43 -0.20 -0.34 1.02 -0.25 -0.88 -0.41 -0.04 -0.08 -0.26
5089 || orf19.3276 || PWP2 || || Putative 90S pre-ribosomal component; repressed in core stress response; repressed by prostaglandins; physically interacts with TAP-tagged Nop1; Hap43-induced || 1 -0.10 -0.10 0.62 0.41 0.14 1.07 -0.45 -0.21 -0.16 0.90 -0.33 -0.91 -0.02 -0.16 0.01 -0.15
5090 || orf19.3276 || PWP2 || || Putative 90S pre-ribosomal component; repressed in core stress response; repressed by prostaglandins; physically interacts with TAP-tagged Nop1; Hap43-induced || 1 -0.20 0.11 0.02 -0.08 0.65 1.07 -0.35 -0.16 -0.31 0.70 -0.15 -0.80 0.13 0.17 -0.28 -0.08
5091 || orf19.6766 || NOP13 || || Ortholog of S. cerevisiae Nop13; a nucleolar protein found in preribosomal complexes; Hap43-induced gene; rat catheter biofilm induced || 1 0.43 0.79 0.27 0.27 0.84 1.90 -0.30 -0.39 -0.89 1.16 -0.46 -1.90 -0.23 0.41 -0.13 0.19
5092 || orf19.3271 || || || Ortholog of Candida albicans WO-1 : CAWG_01442 || 1 0.34 1.27 0.60 -0.27 0.77 -0.23 -0.41 1.08 -0.74 -2.60 -0.43 0.15
5093 || orf19.7371 || ZCF35 || || Zn(II)2Cys6 transcription factor; Hap43-induced; Spider biofilm induced || 1 0.36 0.39 -0.15 -0.12 0.40 0.53 -0.41 -0.31 -0.58 -0.15 -0.44 -0.91 0.31 0.40 -0.37 -0.68
5094 || orf19.1404 || || || Predicted tRNA dihydrouridine synthase; Spider biofilm induced || 1 0.05 -0.22 -0.09 -0.62 0.31 0.62 -0.01 -0.62 -0.49 0.84 -0.08 -0.52 0.18 0.39 0.02 -0.16
5095 || orf19.3463 || || || Putative GTPase; role in 60S ribosomal subunit biogenesis; Spider biofilm induced || 1 0.14 0.38 -0.34 -0.78 0.74 0.65 0.19 -0.39 -0.41 1.38 -0.31 -0.87 -0.02 0.31 0.11 -0.89
5096 || orf19.3463 || || || Putative GTPase; role in 60S ribosomal subunit biogenesis; Spider biofilm induced || 1 0.31 0.25 -0.53 -0.60 1.15 1.06 0.26 -0.64 -0.68 1.12 -0.31 -0.72 -0.04 -0.18 0.36 -1.03
5097 || orf19.6052 || CNS1 || || Putative co-chaperone; Hap43p-induced gene; mutation confers hypersensitivity to radicicol || 1 -0.15 0.39 -0.15 -0.20 0.93 1.50 -0.17 -0.74 -0.95 0.33 -0.32 0.09 0.25 -0.69 0.31 -0.95
5098 || orf19.6052 || CNS1 || || Putative co-chaperone; Hap43p-induced gene; mutation confers hypersensitivity to radicicol || 1 -0.61 -0.17 -0.81 -0.86 1.01 1.45 -0.28 -0.86 -1.05 0.61 0.04 -0.00 -0.34 -0.55 0.65 -1.26
5099 || orf19.3275 || || || Ortholog of C. dubliniensis CD36 : Cd36_25870, C. parapsilosis CDC317 : CPAR2_804000, Candida tenuis NRRL Y-1498 : CANTEDRAFT_115661 and Debaryomyces hansenii CBS767 : DEHA2B05852g || 1 -0.44 -0.28 -0.00 -0.57 0.52 1.51 -0.25 -0.76 -0.62 0.60 -0.05 -0.32 0.14 0.10 -0.02 -0.61
5100 || orf19.4739 || MSS116 || || Putative DEAD-box protein; required for efficient splicing of mitochondrial Group I and II introns; Hap43-induced; rat catheter biofilm induced || 1 -0.13 -0.19 -0.25 -0.73 0.65 1.31 -0.40 -0.38 -0.52 0.91 -0.42 -0.82 0.10 -0.20 0.19 -0.54
5101 || orf19.6234 || || || Putative U2 snRNP component; mutation confers hypersensitivity to 5-fluorocytosine (5-FC), 5-fluorouracil (5-FU), and tubercidin (7-deazaadenosine); Hap43-induced, Spider biofilm induced || 1 0.08 0.29 -0.84 -0.78 0.94 1.27 -0.03 -0.50 -1.10 0.81 -0.15 -1.08 0.42 0.00 -0.12 -0.82
5102 || orf19.4399 || NCS2 || || Putative cytosolic thiouridylase subunit; Spider biofilm induced || 1 -0.01 0.18 -0.04 -0.66 1.11 1.38 0.08 -0.55 -0.76 0.44 -0.38 -0.88 0.33 -0.21 0.02 -0.77
5103 || orf19.4835 || || || Ortholog(s) have role in endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA and LSU-rRNA), more || 1 0.28 0.32 -0.28 -0.99 1.11 1.64 0.21 -0.48 -0.76 -0.21 -0.28 -1.05 0.57 -0.14 -0.50 -0.98
5104 || orf19.970 || || || Protein with a predicted role in microtubule-related processes; Spider biofilm induced || 1 0.32 0.11 -0.47 -0.44 1.49 1.21 -0.38 -0.34 -1.27 -0.26 -0.27 -0.75 -0.13 -0.42 0.04 -0.66
5105 || orf19.2385 || KTI12 || || Protein similar to S. cerevisiae Kti12p, which associates with Elongator complex; has a role in resistance to killer toxin; predicted Kex2p substrate; Hap43p-induced gene || 1 -0.01 -0.29 -0.69 -0.41 1.48 0.93 -0.33 -0.21 -1.22 0.86 -0.23 -0.70 0.06 -0.61 0.08 -0.87
5106 || orf19.4760 || || || Putative protein-histidine N-methyltransferase; Spider biofilm induced || 1 -0.02 -0.18 -1.06 -1.21 0.46 0.39 -0.24 -0.76 -1.43 0.31 -0.49 -1.53 0.19 -0.40 -0.81 -1.45
5107 || orf19.7154 || UTP18 || || Putative U3 snoRNA-associated protein; Hap43-induced; repressed in core stress response; physically interacts with TAP-tagged Nop1 || 1 -0.28 -0.37 -1.13 -1.17 0.54 0.89 -0.13 -0.29 -0.88 0.97 -0.07 -1.42 -0.11 -0.11 -0.19 -0.79
5108 || orf19.7154 || UTP18 || || Putative U3 snoRNA-associated protein; Hap43-induced; repressed in core stress response; physically interacts with TAP-tagged Nop1 || 1 -0.58 -0.38 -1.21 -1.20 0.40 0.59 -0.28 -0.44 -1.01 0.76 -0.25 -1.21 -0.40 -0.20 -0.36 -0.88
5109 || orf19.2688 || NAN1 || || Putative U3 snoRNP protein; Hap43p-induced gene; physically interacts with TAP-tagged Nop1p || 1 -0.58 -0.53 -1.10 -1.53 0.40 0.60 -0.11 -1.02 -1.33 0.68 -0.52 -1.29 0.08 -0.19 -0.30 -0.86
5110 || orf19.2330 || || || Putative U3 snoRNA-associated protein; Hap43-induced; transposon mutation affects filamentous growth; repressed by prostaglandins || 1 -0.66 -0.69 -0.86 -1.11 0.19 0.19 -0.02 -0.62 -0.79 0.92 -0.12 -0.64 0.19 0.13 -0.10 -0.66
5111 || orf19.2830 || RRP9 || || Ribosomal protein; mutation confers resistance to 5-fluorocytosine (5-FC), 5-fluorouracil (5-FU), and tubercidin (7-deazaadenosine); physically interacts with TAP-tagged Nop1; Hap43-induced; Spider biofilm induced || 1 -0.36 -0.35 -0.94 -1.11 0.92 0.61 0.07 -0.84 -1.14 0.93 -0.54 -0.73 0.46 -0.40 0.04 -1.20
5112 || orf19.5608 || || || RNA polymerase III subunit; Spider biofilm induced || 1 -0.16 -0.22 -0.68 -0.45 0.35 0.66 -0.58 -0.72 -1.65 0.89 -0.79 -0.61 -0.01 -0.55 -0.28 -0.63
5113 || orf19.5207 || || || Predicted diphthamide biosynthesis protein; Spider biofilm induced || 1 -0.29 -0.07 -0.63 -0.85 0.62 0.91 -0.34 -0.54 -1.30 1.01 -0.62 -0.56 -0.38 -0.12 0.03 -0.93
5114 || orf19.4268 || UTP13 || || Putative U3 snoRNA-associated protein; Hap43-induced; repressed in core stress response; physically interacts with TAP-tagged Nop1 || 1 -0.19 -0.11 -0.89 -0.74 0.60 1.15 -0.46 -0.60 -1.11 1.02 0.08 -0.41 -0.20 -0.05 -0.04 -0.55
5115 || orf19.5436 || UTP8 || || Essential nucleolar protein; involved in tRNA export from the nucleus and ribosomal small subunit biogenesis; physically interacts with TAP-tagged Nop1; Spider biofilm induced || 1 -0.31 -0.42 -0.51 -0.44 0.31 1.06 -0.56 -0.53 -0.73 0.79 -0.12 -0.54 -0.21 0.02 -0.75 -0.64
5116 || orf19.2688 || NAN1 || || Putative U3 snoRNP protein; Hap43p-induced gene; physically interacts with TAP-tagged Nop1p || 1 -0.16 -0.05 -0.08 -0.59 0.41 0.94 -0.24 -0.83 -0.74 0.69 -0.34 -0.69 0.15 -0.11 -0.53 -0.53
5117 || orf19.5567 || POP4 || || Ortholog of S. cerevisiae Pop4; a subunit of both RNase MRP and nuclear RNase P; filament induced; regulated by Nrg1, Tup1; likely essential, based on UAU1 strategy; rat catheter and Spider biofilm induced || 1 -0.39 -0.28 -0.60 -0.37 0.20 0.68 0.09 -0.65 -0.47 0.39 -0.02 -0.29 -0.02 -0.10 0.05 -0.60
5118 || orf19.4739 || MSS116 || || Putative DEAD-box protein; required for efficient splicing of mitochondrial Group I and II introns; Hap43-induced; rat catheter biofilm induced || 1 -0.60 -0.71 -0.75 -1.17 1.19 1.54 -0.22 -0.12 -0.74 1.29 -0.27 -0.54 -0.36 0.12 0.62 -0.62
5119 || orf19.3300 || ZPR1 || || Protein with putative zinc finger; regulated by Gcn4p; repressed in response to amino acid starvation (3-aminotriazole treatment); upregulation correlates with clinical development of fluconazole resistance || 1 -0.03 -0.20 -0.77 -1.17 1.18 1.16 -0.64 -0.23 -1.16 0.76 -0.09 -0.59 -0.62 0.08 0.56 -0.03
5120 || orf19.5038 || || || Predicted tRNA (guanine) methyltransferase activity; Spider biofilm induced || 1 0.00 -0.05 -0.31 -0.39 0.15 0.86 -0.61 -0.42 -0.92 0.99 -0.22 -0.82 -0.59 0.14 -0.06 -0.25
5121 || orf19.4268 || UTP13 || || Putative U3 snoRNA-associated protein; Hap43-induced; repressed in core stress response; physically interacts with TAP-tagged Nop1 || 1 0.08 0.06 -0.44 -0.12 0.54 0.95 -0.46 -0.22 -1.11 1.00 0.32 -0.62 -0.27 -0.18 0.03 -0.55
5122 || orf19.4870 || DBP3 || || Putative ATP-dependent DEAD-box RNA helicase; Hap43-induced; repressed by prostaglandins; Spider biofilm induced || 1 0.14 0.14 -0.19 -0.10 0.15 0.46 -0.23 -0.11 -1.15 1.26 -0.30 -1.04 -0.39 0.02 -0.58 -0.38
5123 || orf19.2917 || || || Putative GTPase; heterozygous null mutant exhibits resistance to parnafungin in the C. albicans fitness test; Hap43p-induced gene || 1 0.02 -0.06 -0.16 -0.35 0.46 0.45 -0.33 -0.18 -0.98 1.14 -0.37 -1.36 -0.32 -0.25 -0.74 -0.61
5124 || orf19.4870 || DBP3 || || Putative ATP-dependent DEAD-box RNA helicase; Hap43-induced; repressed by prostaglandins; Spider biofilm induced || 1 0.14 0.06 -0.57 -0.51 0.48 0.39 -0.14 -0.12 -0.91 1.03 -0.36 -1.33 0.07 -0.11 -0.58 -0.80
5125 || orf19.171 || DBP2 || || Putative DEAD-box family ATP-dependent RNA helicase; flucytosine induced; repressed in core stress response || 1 -0.24 -0.26 -0.61 -0.57 0.02 0.33 -0.41 -0.16 -1.25 0.46 -0.48 -1.55 -0.16 -0.20 -0.51 -0.83
5126 || orf19.4815 || YTM1 || || Protein similar to S. cerevisiae Ytm1p, which is involved in biogenesis of the large ribosomal subunit; transposon mutation affects filamentous growth; protein level decreases in stationary phase cultures; Hap43p-induced gene || 1 -0.06 -0.12 -0.40 -0.29 -0.13 0.44 -0.35 -0.43 -1.10 0.60 -0.38 -1.57 -0.26 -0.23 -0.96 -0.32
5127 || orf19.7657 || POP3 || || Putative RNase MRP and nuclear RNase P component; decreased repressed by prostaglandins; Spider biofilm induced || 1 -0.02 -0.13 -0.17 -0.49 0.44 0.91 -0.18 -0.39 -0.75 0.63 -1.01 -1.70 -0.16 -0.54 -0.57 -0.53
5128 || orf19.7599 || UTP5 || || Putative U3 snoRNA-associated protein; Hap43p-induced gene; mutation confers resistance to 5-fluorocytosine (5-FC), 5-fluorouracil (5-FU), and tubercidin (7-deazaadenosine); physically interacts with TAP-tagged Nop1p || 1 -0.51 -0.27 -0.21 -0.03 0.00 0.42 -0.68 -0.45 -0.13 0.19 -0.59 -0.81 0.08 -0.32 -0.40 -0.54
5129 || orf19.7052 || || || Putative polyphosphatidylinositol phosphatase; possibly an essential gene, disruptants not obtained by UAU1 method || 1 -0.48 -0.36 -0.13 0.09 -0.16 0.32 -0.61 -0.41 -0.73 0.02 -0.40 -0.60 -0.24 -0.19 -0.12 -0.44
5130 || orf19.5507 || ENP1 || || Protein required for pre-rRNA processing and 40S ribosomal subunit synthesis; associated with U3 and U14 snoRNAs; transposon mutation affects filamentous growth; repressed by prostaglandins; Spider biofilm induced || 1 -0.20 -0.39 -0.71 -0.57 0.02 0.68 -0.44 -0.91 -1.45 1.16 -0.65 -1.27 -0.05 -0.22 -0.56 -2.02
5131 || orf19.7424 || NSA2 || || Putative protein constituent of 66S pre-ribosomal particles; Hap43-induced; repressed by prostaglandins || 1 -0.23 -0.23 0.08 -0.00 0.05 1.35 -0.69 -0.74 -0.80 0.52 -1.06 -1.52 -0.34 -0.27 -0.71 -1.18
5132 || orf19.4701 || || || Ortholog(s) have ATPase activity, tRNA binding activity, role in protein urmylation, regulation of transcription from RNA polymerase II promoter, tRNA wobble uridine modification and Elongator holoenzyme complex localization || 1 -0.10 -0.06 -0.14 -0.34 0.10 0.68 -0.32 -0.23 -0.64 0.13 -0.74 -0.72 -0.08 -0.02 -0.26 -0.65
5133 || orf19.475 || || || Putative rRNA processing protein; rat catheter biofilm induced || 1 0.02 -0.14 -0.75 -0.45 0.20 0.64 -0.29 -1.18 -1.64 0.11 -1.64 -1.98 -0.16 -0.79 -0.65 -1.56
5134 || orf19.1528 || || || Putative mitochondrial RNA polymerase specificity factor; possibly an essential gene, disruptants not obtained by UAU1 method || 1 -0.16 -0.06 -0.14 -0.42 0.17 0.53 -0.57 -0.63 -0.78 0.60 -0.90 -0.72 -0.26 -0.69 -0.23 -1.04
5135 || orf19.1528 || || || Putative mitochondrial RNA polymerase specificity factor; possibly an essential gene, disruptants not obtained by UAU1 method || 1 -0.30 -0.35 -0.40 -0.62 -0.04 0.16 -0.84 -1.03 -1.15 0.25 -1.11 -0.98 -0.60 -0.81 -0.49 -1.36
5136 || orf19.2384 || MTG1 || || Putative mitochondrial GTPase; likely essential for respiratory competence and in large ribosomal subunit assembly; mitochondrial translation; Spider biofilm induced || 1 -0.79 -0.17 -0.11 -0.51 0.37 0.70 -0.65 -1.02 -0.83 -0.01 -0.85 -0.98 -0.25 -0.83 -0.44 -1.29
5137 || orf19.1404 || || || Predicted tRNA dihydrouridine synthase; Spider biofilm induced || 1 -0.40 -0.34 -0.31 -0.34 0.02 0.36 -0.22 -0.44 -0.64 0.20 -0.58 -0.73 -0.12 -0.20 -0.49 -0.88
5138 || orf19.1646 || || || Ortholog(s) have rRNA primary transcript binding activity || 1 -0.49 -0.53 -0.62 -0.55 -0.17 0.78 -0.76 -0.69 -1.26 0.27 -0.67 -1.34 -0.42 -0.18 -0.84 -0.78
5139 || orf19.2193 || PRS5 || || Putative 5-phospho-ribosyl-1(alpha)-pyrophosphate synthetase; Hap43-induced; repressed during core stress response || 1 -0.40 -0.44 -0.41 -0.54 0.22 0.82 -0.62 -0.80 -1.06 -0.03 -0.71 -0.92 -0.59 -0.26 -0.56 -0.79
5140 || orf19.4219 || RIX7 || || Putative ATPase of the AAA family; role in ribosomal subunit export from the nucleus; mutation impairs hyphal growth and biofilm formation || 1 -0.25 -0.27 -0.12 -0.08 0.22 0.51 -0.63 -0.64 -0.51 0.32 -0.53 -0.38 -0.45 -0.38 -0.58 -0.75
5141 || orf19.600 || TRK1 || || Potassium transporter; mediates K+ and Cl- influx; role in sensitivity to cationic antimicrobial peptides, not by direct uptake, possibly related to membrane permeability; contains 5' UTR intron; Spider biofilm induced || 1 -0.22 -0.22 -0.25 -0.26 0.03 0.38 -1.40 -1.19 -1.22 0.03 -1.39 -1.22 -0.70 -0.22 -0.60 -0.56
5142 || orf19.1306 || || || Ortholog(s) have cytosol, nucleus localization || 1 0.22 0.24 -0.38 -0.23 0.14 0.23 -0.81 -1.02 -0.75 -0.23 -1.98 -1.32 -1.15 0.07 -1.08 -1.10
5143 || orf19.1575 || PRS1 || || Phosphoribosylpyrophosphate synthetase; enzyme of purine, pyrimidine, histidine, and tryptophan biosynthesis; essential; flucytosine induced; macrophage/pseudohyphal-induced || 1 0.23 0.09 -0.07 -0.24 -0.10 0.27 -0.84 -0.58 -0.51 0.16 -1.34 -1.24 -0.85 -0.49 -1.12 -0.81
5144 || orf19.1575 || PRS1 || || Phosphoribosylpyrophosphate synthetase; enzyme of purine, pyrimidine, histidine, and tryptophan biosynthesis; essential; flucytosine induced; macrophage/pseudohyphal-induced || 1 -0.16 0.01 -0.56 -0.55 -0.33 0.12 -0.89 -0.98 -1.30 -0.14 -1.46 -1.64 -1.27 -0.79 -1.25 -0.98
5145 || orf19.1957 || CYC3 || || Mitochondrial cytochrome c heme lyase; antigenic cell-wall protein; filament induced; induced on polystyrene adherence, interaction with macrophage; N-glycosylation, 2 heme-binding motifs; rat catheter, Spider biofilm induced || 1 -0.20 -0.27 -0.55 -0.67 -0.65 -0.06 -0.54 -1.04 -0.60 0.10 -1.45 -1.16 -0.84 -0.65 -1.14 -1.25
5146 || orf19.1957 || CYC3 || || Mitochondrial cytochrome c heme lyase; antigenic cell-wall protein; filament induced; induced on polystyrene adherence, interaction with macrophage; N-glycosylation, 2 heme-binding motifs; rat catheter, Spider biofilm induced || 1 -0.24 -0.26 -0.28 -0.49 -0.95 0.37 -0.60 -1.03 -0.37 0.37 -1.53 -0.90 -1.00 -0.50 -0.92 -0.66
5147 || orf19.3778 || || || Protein with a predicted role in ribosome biogenesis; mutation confers hypersensitivity to 5-fluorocytosine (5-FC), 5-fluorouracil (5-FU); repressed in core stress response; repressed by prostaglandins; Hap43-induced || 1 -0.09 -0.27 -0.43 -0.11 -0.17 0.42 -0.36 -0.34 -0.15 0.39 -0.47 -1.07 -0.47 -0.28 -0.65 -0.37
5148 || orf19.6442 || PRP8 || || Protein similar to S. cerevisiae Prp8, a component of the U4/U6-U5 snRNP complex; repressed by alpha pheromone in SpiderM medium || 1 -0.21 -0.04 -0.01 -0.14 0.57 0.37 -0.54 -0.10 -0.51 -0.22 -0.33 -0.60 -0.32 -0.30 -0.29 -0.41
5149 || orf19.6442 || PRP8 || || Protein similar to S. cerevisiae Prp8, a component of the U4/U6-U5 snRNP complex; repressed by alpha pheromone in SpiderM medium || 1 -0.46 -0.38 -0.23 -0.23 0.51 0.34 -1.26 -0.68 -1.06 -0.37 -0.67 -0.80 -0.81 -0.78 -0.71 -0.58
5150 || orf19.3098 || || || Predicted RNA-dependent ATPase RNA helicase; Hap43-induced gene || 1 -0.34 -0.24 -0.28 -0.46 0.26 0.55 -1.08 -0.57 -0.90 0.18 -0.25 -0.50 -0.68 -0.10 -0.34 -0.21
5151 || orf19.5847 || || || Ortholog(s) have RNA polymerase III activity, role in tRNA transcription from RNA polymerase III promoter and DNA-directed RNA polymerase III complex, cytosol localization || 1 -0.47 -0.40 -0.55 -0.45 0.10 0.36 -0.74 -0.47 -0.95 0.24 -0.45 -0.83 -0.94 -0.36 -0.67 -0.25
5152 || orf19.7215 || || || Nucleolar protein; component of the small subunit processome containing the U3 snoRNA; involved in pre-18S rRNA processing; flow model biofilm repressed || 1 -0.38 -0.44 -0.22 -0.41 0.28 0.41 -0.80 -0.56 -0.77 0.36 -0.42 -0.55 -1.01 -0.14 -1.09 0.34
5153 || orf19.5884 || || || Putative nucleolar preribosomal-associated protein; decreased transcription is observed upon benomyl treatment or in an azole-resistant strain that overexpresses MDR1; Spider biofilm induced || 1 0.23 -0.31 -0.14 0.02 0.19 0.62 -0.56 -0.18 -0.64 0.21 -0.09 -0.68 -0.81 -0.49 -0.68 -0.24
5154 || orf19.969 || || || Ortholog(s) have ribose phosphate diphosphokinase activity, role in 5-phosphoribose 1-diphosphate biosynthetic process, cytokinesis, fungal-type cell wall organization and cytosol, nucleus localization || 1 0.14 -0.08 0.01 0.16 0.15 0.63 -0.64 -0.24 -0.54 0.01 -0.48 -0.38 -0.67 -0.52 -0.99 -0.47
5155 || orf19.5906 || ADE2 || || Phosphoribosylaminoimadazole carboxylase; role in adenine biosynthesis; required for normal growth and virulence in immunosuppressed mouse infection; not induced in GCN response, in contrast to S. cerevisiae ADE2; stationary phase-enriched || 1 0.17 0.09 -0.20 -0.33 0.05 0.46 -0.85 -0.41 -0.52 -0.09 -0.30 -0.49 -1.03 -0.57 -0.68 -0.82
5156 || orf19.4420 || || || Predicted component of the core factor rDNA transcription factor complex; required for transcription of 35S rRNA genes by RNA polymerase I in S. cerevisiae; possibly an essential gene, disruptants not obtained by UAU1 method || 1 0.14 0.29 0.20 0.01 0.08 0.57 -0.51 -0.56 -0.36 -0.14 -0.32 -0.33 -0.57 -0.72 -0.59 -0.27
5157 || orf19.5356 || || || Protein with a predicted role in cell wall integrity; repressed in core stress response || 1 0.00 -0.03 0.23 0.33 0.37 0.69 -0.53 -0.56 -0.45 0.37 -0.41 -0.72 -0.22 -0.91 -0.27 -0.34
5158 || orf19.1923 || RRN3 || || Protein with a predicted role in recruitment of RNA polymerase I to rDNA; caspofungin induced; flucytosine repressed; repressed in core stress response; repressed by prostaglandins || 1 -0.31 -0.34 -0.07 -0.05 0.83 1.04 -0.60 -0.51 -0.60 0.27 -0.65 -1.20 0.03 -1.00 -0.18 -0.90
5159 || orf19.1646 || || || Ortholog(s) have rRNA primary transcript binding activity || 1 -0.32 -0.12 -0.49 -0.55 0.84 0.99 -0.86 -0.59 -1.35 0.43 -0.82 -1.49 -0.82 -0.10 -0.61 -0.62
5160 || orf19.3159 || UTP20 || || Putative snoRNA-binding protein; S. cerevisiae Utp20 ortholog; likely essential for growth; repressed in core stress response; mutation confers resistance to 5-fluorocytosine (5-FC) and parnafungin || 1 0.02 -0.05 -0.56 -0.33 0.32 1.15 -1.12 -0.92 -1.71 0.77 -0.85 -1.36 -0.69 -0.32 -0.61 -0.99
5161 || orf19.2504 || BMS1 || || Putative GTPase; Hap43-induced gene; mutation confers resistance to 5-fluorocytosine (5-FC); flucytosine induced; repressed by prostaglandins; Spider biofilm induced || 1 0.39 0.29 -0.41 -0.54 0.60 0.88 -0.64 -0.59 -1.87 0.17 -0.54 -1.53 -0.85 -0.83 -0.69 -0.90
5162 || orf19.2778 || || || Protein of unknown function; transcript is upregulated in clinical isolates from HIV+ patients with oral candidiasis || 1 0.93 0.40 -0.20 -0.75 0.97 1.25 -0.66 -0.92 -1.67 0.16 -1.20 -1.81 -0.59 -0.54 -0.69 -0.49
5163 || orf19.6902 || DBP7 || || Putative ATP-dependent DEAD-box RNA helicase; Hap43-induced; rat catheter biofilm induced || 1 0.30 0.40 -0.03 -0.43 0.85 1.27 -0.80 -0.74 -1.40 0.50 -0.94 -1.58 -0.80 -0.20 -0.95 -0.74
5164 || orf19.2527 || || || Putative protein of unknown function; Hap43-induced; required for normal biofilm growth; F-12/CO2 early biofilm induced || 1 0.26 0.22 -0.05 -0.56 1.30 1.44 -0.67 -0.62 -1.49 0.09 -0.95 -2.09 -0.19 -0.21 -0.72 -0.88
5165 || orf19.3130 || || || Ortholog of S. cerevisiae Gpn3 a GTPase with a role in biogenesis of RNA pol II and polIII; possibly an essential gene, disruptants not obtained by UAU1 method || 1 0.24 0.23 0.11 -0.07 0.73 1.49 -0.45 -0.87 -0.96 0.36 -0.82 -0.44 -0.63 -0.10 -0.03 -0.60
5166 || orf19.4363 || SGD1 || || Predicted small ribosomal subunit biogenesis protein; repressed in core stress response; transcript increases in populations of cells exposed to fluconazole over multiple generations; Spider biofilm induced || 1 0.31 0.09 0.04 -0.13 0.52 1.38 -0.53 -1.06 -0.97 0.54 -0.62 -0.60 -0.82 -0.16 -0.51 -0.88
5167 || orf19.5229 || || || Ortholog(s) have 3'-5'-exoribonuclease activity, endoribonuclease activity, tRNA binding activity || 1 0.19 0.24 -0.37 -0.08 0.52 0.89 -0.59 -0.74 -0.85 0.70 -0.51 -0.48 -0.63 -0.23 -0.36 -0.56
5168 || orf19.5356 || || || Protein with a predicted role in cell wall integrity; repressed in core stress response || 1 -0.17 -0.05 0.05 -0.18 0.57 0.80 -0.49 -0.50 -0.86 0.57 -0.45 -0.77 -0.44 -0.34 -0.05 -0.81
5169 || orf19.2090 || || || Ortholog of S. cerevisiae Ecm16, an essential DEAH-box ATP-dependent RNA helicase specific to the U3 snoRNP required for 18S rRNA synthesis; Hap43-induced; Spider biofilm induced || 1 -0.09 -0.02 0.35 0.14 0.86 1.18 -0.73 -0.77 -0.84 0.70 -0.49 -1.30 -0.65 -0.37 -0.61 -1.27
5170 || orf19.6175 || || || Putative 35S rRNA processing protein; Hap43-induced; repressed by prostaglandins; Spider biofilm induced || 1 -0.22 -0.05 0.55 0.36 0.31 1.08 -0.60 -0.77 -0.61 0.40 -0.61 -0.72 -0.46 -0.73 -0.39 -1.11
5171 || orf19.5206 || || || Putative chaperone protein; role in the assembly of box H/ACA snoRNPs and thus for pre-rRNA processing; Spider biofilm induced || 1 -0.09 -0.18 0.06 -0.02 0.65 1.33 -0.79 -1.20 -1.49 -0.14 -1.31 -1.22 -0.32 -0.62 -0.73 -1.81
5172 || orf19.4363 || SGD1 || || Predicted small ribosomal subunit biogenesis protein; repressed in core stress response; transcript increases in populations of cells exposed to fluconazole over multiple generations; Spider biofilm induced || 1 0.09 0.14 0.25 0.18 0.43 0.94 -0.55 -0.85 -1.22 0.39 -0.86 -0.82 -0.45 -0.62 -0.63 -0.97
5173 || orf19.5206 || || || Putative chaperone protein; role in the assembly of box H/ACA snoRNPs and thus for pre-rRNA processing; Spider biofilm induced || 1 0.22 0.32 0.32 0.12 0.74 1.21 -0.56 -0.89 -0.75 -0.01 -1.05 -1.03 -0.19 -0.98 -0.50 -1.07
5174 || orf19.6691 || || || Putative ember of the multi-drug and toxin extrusion (MATE) family of the multidrug/oligosaccharidyl-lipid/polysaccharide exporter superfamily; Spider biofilm induced || 1 0.34 0.23 0.10 0.20 0.48 0.76 -0.23 -0.98 -0.78 0.10 -1.15 -0.46 -0.62 -0.40 -0.63 -0.89
5175 || orf19.2778 || || || Protein of unknown function; transcript is upregulated in clinical isolates from HIV+ patients with oral candidiasis || 1 0.63 0.74 0.09 -0.54 1.15 1.15 -0.63 -1.23 -1.36 0.36 -0.74 -0.97 -0.23 -0.21 -0.34 -0.69
5176 || orf19.3393 || || || Putative DEAD-box helicase; Hap43-induced; Spider biofilm induced || 1 0.58 0.29 0.43 0.28 0.44 0.96 -0.47 -0.87 -0.98 0.85 -0.80 -1.57 -0.45 -0.41 -0.99 -1.19
5177 || orf19.3393 || || || Putative DEAD-box helicase; Hap43-induced; Spider biofilm induced || 1 0.58 0.60 -0.09 -0.00 0.54 1.17 -0.42 -1.02 -1.32 0.80 -0.64 -1.45 -0.22 -0.24 -0.81 -1.36
5178 || orf19.3393 || || || Putative DEAD-box helicase; Hap43-induced; Spider biofilm induced || 1 0.56 0.68 0.35 0.09 0.62 1.08 -0.29 -0.58 -0.89 0.80 -0.48 -1.49 0.24 -0.20 -0.90 -0.95
5179 || orf19.5010 || DIM1 || || Putative 18S rRNA dimethylase; predicted role in rRNA modification and processing; Hap43-induced; likely to be essential for growth based on insertional mutagenesis strategy; F-12/CO2 early biofilm induced || 1 0.48 0.64 0.38 0.39 0.78 1.37 -0.05 -0.77 -1.03 1.22 -0.76 -1.85 0.12 -0.07 -0.79 -1.43
5180 || orf19.3393 || || || Putative DEAD-box helicase; Hap43-induced; Spider biofilm induced || 1 0.29 0.47 0.35 0.01 0.53 1.13 -0.22 -0.65 -0.83 0.80 -0.63 -1.36 -0.07 0.02 -0.64 -1.43
5181 || orf19.7398 || || || Protein of unknown function' Hap43-induced gene; repressed by prostaglandins || 1 0.66 0.65 0.34 0.16 0.94 1.54 -0.36 -0.43 -1.01 0.56 -0.67 -1.69 -0.10 -0.00 -0.45 -1.48
5182 || orf19.7424 || NSA2 || || Putative protein constituent of 66S pre-ribosomal particles; Hap43-induced; repressed by prostaglandins || 1 0.21 0.43 0.41 0.27 0.53 1.28 -0.41 -0.59 -0.78 0.51 -0.76 -1.82 -0.09 -0.45 -0.71 -1.75
5183 || orf19.7618 || || || Putative nucleolar protein with a predicted role in pre-18S rRNA processing; Plc1p-regulated; Spider biofilm induced || 1 0.51 0.45 -0.07 -0.23 0.79 1.23 -0.12 -0.42 -1.15 0.56 -0.97 -1.70 -0.33 -0.25 -0.46 -1.59
5184 || orf19.7618 || || || Putative nucleolar protein with a predicted role in pre-18S rRNA processing; Plc1p-regulated; Spider biofilm induced || 1 0.62 0.51 -0.08 -0.36 0.70 1.15 -0.17 -0.51 -1.03 0.54 -1.02 -1.82 -0.30 -0.19 -0.56 -1.10
5185 || orf19.3159 || UTP20 || || Putative snoRNA-binding protein; S. cerevisiae Utp20 ortholog; likely essential for growth; repressed in core stress response; mutation confers resistance to 5-fluorocytosine (5-FC) and parnafungin || 1 0.62 0.63 0.07 0.08 1.17 1.36 -0.26 -0.48 -0.98 1.30 -0.34 -1.09 -0.01 -0.17 -0.36 -0.90
5186 || orf19.6902 || DBP7 || || Putative ATP-dependent DEAD-box RNA helicase; Hap43-induced; rat catheter biofilm induced || 1 0.44 0.56 0.02 -0.29 1.04 1.42 -0.19 -0.36 -0.83 0.87 -0.54 -1.07 -0.11 0.42 -0.13 -0.72
5187 || orf19.5407 || SOF1 || || Putative protein with a predicted role in 40S ribosomal subunit biogenesis; rat catheter biofilm induced || 1 0.33 0.39 0.46 -0.39 1.41 1.87 -0.51 -0.71 -1.25 0.75 -0.24 -0.92 -0.01 -0.09 0.09 -0.87
5188 || orf19.2143 || || || Ortholog(s) have role in endocytic recycling and cytosol, endosome, nucleus localization || 1 0.13 -0.09 0.27 -0.05 0.70 1.22 -0.28 -0.33 -0.43 0.51 -0.21 -0.47 0.05 -0.36 0.05 -0.43
5189 || orf19.661 || KRR1 || || Putative nucleolar protein; repressed benomyl treatment or in an azole-resistant strain that overexpresses MDR1; F-12/CO2 early biofilm induced || 1 0.01 0.24 0.47 0.21 1.19 1.98 -0.04 -0.21 -0.58 1.24 -0.32 -0.99 0.25 0.09 -0.33 -1.32
5190 || orf19.6652 || DBP8 || || Protein similar to S. cerevisiae Dbp8p, an ATP-dependent helicase involved in rRNA processing; oxidative stress-repressed via Cap1p; flucytosine repressed; likely to be essential for growth, based on insertional mutagenesis || 1 0.08 0.47 0.57 -0.16 0.99 1.64 -0.19 -0.70 -0.63 0.60 -0.54 -0.94 -0.07 -0.08 -0.57 -1.46
5191 || orf19.603 || IMP4 || || Putative SSU processome component; Hap43-induced; repressed by prostaglandins; Spider biofilm induced || 1 0.19 0.14 0.24 -0.17 0.61 1.41 -0.27 -0.58 -0.73 0.62 -0.62 -0.82 -0.01 -0.16 -0.19 -0.88
5192 || orf19.603 || IMP4 || || Putative SSU processome component; Hap43-induced; repressed by prostaglandins; Spider biofilm induced || 1 0.34 0.34 0.45 0.09 0.89 1.61 -0.19 -0.68 -0.79 0.76 -0.67 -1.11 0.05 -0.31 -0.10 -1.03
5193 || orf19.5732 || NOG2 || || Putative nucleolar GTPase; repressed by prostaglandins; Hap43-induced, rat catheter and Spider biofilm induced || 1 0.20 0.12 0.59 0.29 0.65 1.62 -0.03 -0.61 -0.53 0.80 -1.00 -0.90 0.09 -0.40 -0.22 -1.17
5194 || orf19.4219 || RIX7 || || Putative ATPase of the AAA family; role in ribosomal subunit export from the nucleus; mutation impairs hyphal growth and biofilm formation || 1 -0.03 -0.09 0.02 0.13 0.31 0.68 -0.10 -0.21 -0.34 0.36 -0.32 -0.42 -0.27 -0.13 0.02 -0.35
5195 || orf19.6259 || || || Exosome non-catalytic core component; involved in 3'-5' RNA processing and degradation in the nucleus and cytoplasm; Spider biofilm induced || 1 0.08 0.27 -0.11 0.11 0.56 0.77 0.01 -0.45 -0.50 0.52 -0.15 -0.27 0.06 -0.14 -0.17 -0.28
5196 || orf19.7657 || POP3 || || Putative RNase MRP and nuclear RNase P component; decreased repressed by prostaglandins; Spider biofilm induced || 1 0.22 0.41 0.21 0.12 0.87 1.42 -0.29 -0.25 -0.86 1.08 -0.65 -0.54 -0.49 -0.34 -0.56 -0.44
5197 || orf19.4479 || || || Putative U3-containing 90S preribosome subunit; Hap43-induced; repressed in core stress response; Spider biofilm induced || 1 1.03 0.59 0.34 0.08 1.24 1.46 -0.13 -0.25 -1.29 1.01 -0.59 -0.14 -0.43 -0.11 -0.49 -0.81
5198 || orf19.5229 || || || Ortholog(s) have 3'-5'-exoribonuclease activity, endoribonuclease activity, tRNA binding activity || 1 0.36 0.68 -0.13 0.11 0.41 0.61 -0.36 -0.33 -0.34 0.75 -0.55 -0.63 -0.51 -0.24 -0.28 -0.67
5199 || orf19.5507 || ENP1 || || Protein required for pre-rRNA processing and 40S ribosomal subunit synthesis; associated with U3 and U14 snoRNAs; transposon mutation affects filamentous growth; repressed by prostaglandins; Spider biofilm induced || 1 0.08 -0.01 0.06 0.33 0.14 0.92 -0.51 -0.96 -1.22 0.57 -0.54 -1.03 0.08 -0.53 -0.58 -1.99
5200 || orf19.2319 || || || Putative nucleolar protein with a predicted role in pre-rRNA processing; Hap43-induced gene; repressed in core stress response || 1 0.20 0.21 0.13 0.27 0.43 0.82 -0.47 -0.35 -0.75 0.73 -0.03 -0.65 0.28 0.34 -0.22 -0.86
5201 || orf19.6405 || || || Protein of unknown function; decreased transcription is observed in an azole-resistant strain that overexpresses MDR1 || 1 -0.61 0.16 -0.12 -0.51 0.30 0.53 -0.73 -0.68 -1.45 0.34 -0.53 -0.49 -0.03 -0.32 -0.98 -0.19
5202 || orf19.1849 || || || Ortholog(s) have U3 snoRNA binding, rRNA binding activity, role in maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) and nucleolus, small-subunit processome localization || 1 -0.23 -0.16 -0.44 -0.55 0.47 0.39 -0.17 -0.72 -0.80 -0.07 -0.53 -0.49 -0.03 -0.65 -0.49 -0.42
5203 || orf19.1026 || || || Ortholog(s) have role in exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA and LSU-rRNA), more || 1 -0.14 0.07 -0.93 -0.95 0.47 0.01 -0.34 -0.50 -1.43 0.03 -0.14 -0.54 0.30 -0.88 -0.04 -0.50
5204 || orf19.1543 || OPI1 || || Leucine zipper transcription factor; repressor of INO1 involved in inositol biosynthesis; functional homolog of S. cerevisiae Opi1; has putative Opi1-Sin3 interaction domain; interacts with ScSin3, but not CaSin3 || 1 0.01 -0.13 -0.59 -0.22 0.06 0.08 -0.37 -0.61 -0.87 0.26 -0.10 0.04 0.20 -0.18 -0.18 -0.30
5205 || orf19.2676 || || || Predicted hexameric RecA-like ATPase Elp456 Elongator subcomplex subunit; required for modification of wobble nucleosides in tRNA; Spider biofilm induced || 1 -0.17 -0.30 -0.48 -0.05 0.24 0.75 0.09 -0.44 -0.87 0.44 -0.29 -0.20 -0.50 -0.52 -0.27 -0.20
5206 || orf19.3547 || || || Ortholog(s) have mRNA 3'-UTR binding, translation repressor activity, nucleic acid binding activity, role in negative regulation of translation, ribosomal large subunit biogenesis and large ribosomal subunit, nucleolus localization || 1 -0.08 -0.11 -0.57 -0.60 0.22 0.12 -0.25 0.15 -0.61 0.91 -0.03 -0.58 -0.28 0.24 -0.02 0.50
5207 || orf19.3547 || || || Ortholog(s) have mRNA 3'-UTR binding, translation repressor activity, nucleic acid binding activity, role in negative regulation of translation, ribosomal large subunit biogenesis and large ribosomal subunit, nucleolus localization || 1 -0.10 -0.08 -0.69 -0.26 0.35 0.51 -0.25 0.37 -1.08 1.12 0.13 -0.70 -0.52 0.07 -0.70 0.02
5208 || orf19.7011 || || || Ortholog(s) have 90S preribosome, cytoplasm, mitotic spindle pole body, nucleolus localization || 1 -0.13 -0.12 -1.17 -0.76 0.36 0.31 -0.04 0.69 -1.09 1.07 0.35 -0.40 -0.78 0.20 -0.52 0.12
5209 || orf19.3015 || ARX1 || || Putative ribosomal large subunit biogenesis protein; repressed in core stress response; repressed by prostaglandins || 1 0.10 0.16 -1.33 -1.17 0.72 0.56 -0.08 0.42 -1.67 0.89 0.08 -1.03 -0.62 0.26 -0.54 0.23
5210 || orf19.501 || || || Ortholog(s) have RNA methyltransferase activity, role in maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) and nucleolus, preribosome, large subunit precursor localization || 1 -0.04 -0.07 -1.13 -1.13 0.77 0.98 -0.23 0.15 -1.07 0.76 -0.00 -0.51 -1.06 0.27 -0.76 0.03
5211 || orf19.501 || || || Ortholog(s) have RNA methyltransferase activity, role in maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) and nucleolus, preribosome, large subunit precursor localization || 1 -0.11 -0.20 -0.77 -0.85 0.40 0.84 -0.56 0.00 -0.77 0.74 -0.17 -0.50 -0.65 0.18 -0.72 0.07
5212 || orf19.5850 || NOC2 || || Putative nucleolar complex protein; Hap43-induced; transposon mutation affects filamentous growth; mutation confers hypersensitivity to 5-fluorouracil (5-FU), tubercidin (7-deazaadenosine); repressed in core stress response || 1 -0.07 -0.26 -0.87 -0.93 0.41 1.05 -0.30 0.14 -1.07 1.09 -0.03 -1.00 -0.87 0.49 -0.61 0.26
5213 || orf19.5850 || NOC2 || || Putative nucleolar complex protein; Hap43-induced; transposon mutation affects filamentous growth; mutation confers hypersensitivity to 5-fluorouracil (5-FU), tubercidin (7-deazaadenosine); repressed in core stress response || 1 -0.18 -0.13 -0.65 -0.83 0.51 0.84 -0.30 0.28 -0.43 1.34 -0.10 -0.95 -0.55 0.19 -0.77 0.08
5214 || orf19.4640 || PWP1 || || Putative rRNA processing protein; Hap43-induced; repressed in core stress response || 1 -0.34 -0.11 -0.60 -0.58 0.34 1.13 -0.19 0.27 -0.83 1.25 0.34 -0.45 -0.31 0.42 -0.29 0.14
5215 || orf19.512 || || || Ortholog of S. cerevisiae Kre33; essential; S. cerevisiae ortholog is essential and is required for biogenesis of the small ribosomal subunit || 1 -0.51 -0.31 -0.82 -0.88 0.00 0.44 -0.33 0.08 -0.63 0.92 -0.07 -0.46 -0.37 0.04 -0.15 0.23
5216 || orf19.1566 || UTP21 || || Putative U3 snoRNP protein; Hap43-induce; physically interacts with TAP-tagged Nop1; Spider biofilm induced || 1 -0.63 -0.51 -1.06 -0.68 0.17 0.27 -0.74 -0.11 -0.77 1.04 -0.03 -0.65 -0.59 -0.03 -0.59 -0.03
5217 || orf19.3556 || || || Transportin or cytosolic karyopherin beta; Spider biofilm induced || 1 -0.38 -0.23 -1.05 -0.70 0.17 0.09 -0.21 0.32 -0.87 0.84 0.17 -0.18 -0.02 0.06 -0.36 -0.05
5218 || orf19.1124.2 || || || Ortholog(s) have diphthine synthase activity, role in peptidyl-diphthamide biosynthetic process from peptidyl-histidine and cytosol, nucleus localization || 1 -0.28 -0.32 -0.87 -0.63 0.61 0.66 0.04 0.32 -0.57 0.52 0.31 -0.27 -0.83 -0.16 -0.05 -0.18
5219 || orf19.6676 || || || Has domain(s) with predicted diphthine synthase activity and role in peptidyl-diphthamide biosynthetic process from peptidyl-histidine || 1 -0.28 -0.26 -0.60 -0.46 0.62 0.66 -0.05 0.38 -0.59 0.62 0.17 -0.37 -0.90 -0.08 -0.03 0.07
5220 || orf19.2676 || || || Predicted hexameric RecA-like ATPase Elp456 Elongator subcomplex subunit; required for modification of wobble nucleosides in tRNA; Spider biofilm induced || 1 -0.34 -0.36 -0.71 -0.61 0.09 0.58 -0.15 -0.21 -0.67 0.60 -0.21 -0.13 -0.38 0.29 -0.04 -0.23
5221 || orf19.6828 || || || Ortholog(s) have role in rRNA processing and nucleolus, preribosome, large subunit precursor localization || 1 0.10 -0.27 -0.37 -1.25 0.33 1.20 -0.31 0.18 -1.18 0.74 0.23 -0.98 -0.56 -0.31 -0.74 -0.66
5222 || orf19.1030 || || || Putative peptidyl-prolyl cis-trans isomerase || 1 0.28 0.33 -0.66 -0.75 0.58 0.51 -0.56 0.10 -0.95 0.37 -0.04 -0.83 -1.02 -0.41 -1.48 -0.17
5223 || orf19.3962 || HAS1 || || Functional homolog of S. cerevisiae Has1p, which is a nucleolar protein of the DEAD-box ATP-dependent RNA helicase family that is involved in biogenesis of the ribosome, particularly the small (40S) subunit; caspofungin-downregulated || 1 0.13 0.12 -0.50 -0.78 0.23 0.60 -0.62 -0.22 -1.13 0.47 -0.12 -1.11 -1.28 -0.22 -1.09 -0.19
5224 || orf19.3962 || HAS1 || || Functional homolog of S. cerevisiae Has1p, which is a nucleolar protein of the DEAD-box ATP-dependent RNA helicase family that is involved in biogenesis of the ribosome, particularly the small (40S) subunit; caspofungin-downregulated || 1 0.32 0.22 -0.74 -0.77 0.62 0.66 -0.40 0.08 -0.89 0.79 -0.18 -1.00 -0.94 -0.05 -0.83 0.10
5225 || orf19.920 || RMT2 || || Minor protein arginine methyltransferases (PRMT) involved in methylation of arginine residues || 1 0.36 0.21 -0.20 -0.19 0.73 0.99 -0.43 -0.14 -0.59 0.74 -0.49 -0.72 -0.99 -0.06 -0.66 -0.22
5226 || orf19.4401 || YVH1 || || Putative dual specificity phosphatase (phosphoserine/threonine and phosphotyrosine phosphatase); required for wild-type growth rate and for wild-type virulence in mouse model of systemic infection; Hap43p-induced gene || 1 0.07 0.22 -0.04 -1.00 0.88 1.39 -0.22 0.29 -0.72 0.32 -0.41 -0.51 -0.40 -0.19 0.26 -0.32
5227 || orf19.1565 || || || Protein of unknown function || 1 -0.15 0.13 -0.22 -0.27 0.58 0.90 -0.03 0.25 -0.33 0.49 0.25 -0.39 -0.35 0.21 0.03 0.32
5228 || orf19.4746 || JIP5 || || Ortholog of S. cerevisiae Jip5; predicted role in biogenesis of the large ribosomal subunit; repressed in core stress response; Hap43-induced gene || 1 -0.07 0.26 -0.82 -1.01 1.21 1.58 0.34 -0.13 -0.23 0.92 0.21 -0.64 -0.54 0.37 0.21 -0.24
5229 || orf19.429 || || || Putative non-canonical poly(A) polymerase; repressed by nitric oxide; Spider biofilm induced || 1 -0.69 -0.05 -0.37 -0.44 0.50 0.99 0.03 -0.22 -0.20 0.65 -0.04 -0.25 -0.36 -0.15 0.09 -0.38
5230 || orf19.6137 || || || Ortholog of C. dubliniensis CD36 : Cd36_32940, Candida tenuis NRRL Y-1498 : CANTEDRAFT_134955, Debaryomyces hansenii CBS767 : DEHA2E04422g and Pichia stipitis Pignal : PICST_33357 || 1 -0.32 -0.49 -0.17 -0.39 0.49 1.21 -0.33 -0.38 -0.30 0.33 -0.03 -0.06 -0.30 -0.11 -0.14 0.05
5231 || orf19.5436 || UTP8 || || Essential nucleolar protein; involved in tRNA export from the nucleus and ribosomal small subunit biogenesis; physically interacts with TAP-tagged Nop1; Spider biofilm induced || 1 -0.04 -0.00 -0.45 -0.66 0.46 1.05 -0.29 -0.55 -0.61 0.69 0.05 -0.17 -0.06 -0.07 -0.54 0.24
5232 || orf19.2266 || || || Ortholog(s) have ATPase activity, DNA binding, nucleosome binding activity, role in chromatin remodeling and Isw1 complex localization || 1 -0.06 -0.36 -0.12 -0.18 0.59 0.26 -0.29 -0.34 -0.49 0.12 -0.21 -0.33 -0.74 -0.37 -0.09 0.03
5233 || orf19.5425 || || || Ortholog(s) have 3'-tRNA processing endoribonuclease activity, role in tRNA 3'-trailer cleavage, endonucleolytic and mitochondrion, nucleus localization || 1 -0.03 0.02 -0.06 -0.43 0.45 0.52 -0.30 -0.21 -0.36 0.20 -0.09 -0.23 -0.88 -0.46 -0.31 -0.26
5234 || orf19.5425 || || || Ortholog(s) have 3'-tRNA processing endoribonuclease activity, role in tRNA 3'-trailer cleavage, endonucleolytic and mitochondrion, nucleus localization || 1 -0.14 -0.19 -0.47 -0.72 0.76 0.61 -0.23 -0.23 -0.13 0.15 0.05 -0.31 -0.61 -0.41 -0.20 -0.20
5235 || orf19.4697 || MDN1 || || Putative midasin, a very large dynein-related AAA-type ATPase; induced during the mating process || 1 0.41 0.33 -0.50 -0.40 1.73 0.55 -0.50 0.24 -0.54 0.37 -0.01 -0.52 -1.04 -0.68 -0.01 0.09
5236 || orf19.900 || NSP1 || || Essential component of the nuclear pore complex; sumoylation target; stationary phase enriched protein; rat catheter biofilm repressed || 1 0.12 0.22 -0.27 -0.68 0.80 0.38 -0.19 -0.02 -0.67 -0.41 -0.04 -0.49 -0.37 -0.44 0.45 -0.31
5237 || orf19.4578 || CYT2 || || Cytochrome c1 heme lyase; transcript regulated by Nrg1; induced in high iron || 1 0.26 0.14 -0.26 -0.69 0.56 0.36 0.01 -0.05 -0.58 0.02 -0.50 -0.36 -0.90 -0.21 0.10 -0.59
5238 || orf19.1754 || || || Putative calmodulin-dependent protein kinase; possibly an essential gene, disruptants not obtained by UAU1 method || 1 0.18 0.10 -0.28 -0.20 0.34 0.18 -0.11 -0.04 -0.18 -0.10 -0.10 0.14 -0.78 -0.09 -0.13 -0.05
5239 || orf19.1754 || || || Putative calmodulin-dependent protein kinase; possibly an essential gene, disruptants not obtained by UAU1 method || 1 0.24 0.12 -0.32 -0.39 0.43 0.02 -0.22 -0.11 -0.21 -0.23 -0.13 0.06 -0.80 -0.32 -0.20 0.00
5240 || orf19.4404 || PGA49 || || Putative GPI-anchored protein || 1 -0.07 -0.15 -0.19 -0.61 -0.34 -0.13 0.32 0.06 -0.26 -0.20 -0.44 -0.05 -0.44 -0.77 0.25
5241 || orf19.7108 || || || D-ribulose-5-phosphate 3-epimerase; stationary phase enriched protein || 1 -0.26 -0.20 -0.38 -0.62 -0.36 0.39 -0.10 -0.31 -0.17 -0.17 -0.44 -0.19 -0.31 -0.44 0.30 -0.62
5242 || orf19.2445 || || || Putative dicarboxylic amino acid permease; fungal-specific (no human or murine homolog); induced by alpha pheromone in SpiderM medium || 1 -0.08 -0.08 -0.47 -0.88 -0.09 0.37 -0.63 -0.21 -1.02 -0.32 -0.97 -0.42 -1.08 -1.11 -0.06 -1.49
5243 || orf19.7614 || || || Protein of unknown function; Hap43-induced gene; mutant is viable || 1 -0.46 -0.29 0.10 -1.20 -0.09 0.14 -0.46 -0.39 -0.48 -0.40 -0.56 -0.68 -0.30 -0.80 -0.46 -0.50
5244 || orf19.2330 || || || Putative U3 snoRNA-associated protein; Hap43-induced; transposon mutation affects filamentous growth; repressed by prostaglandins || 1 -0.13 -0.09 -0.23 0.01 -0.16 -0.13 -0.45 -0.49 -0.52 0.22 -0.17 -0.49 0.11 -0.41 -0.11 -0.65
5245 || orf19.2018 || || || Protein with a predicted DnaJ chaperone domain and a CSL-type zinc finger; Spider biofilm induced || 1 -0.07 -0.09 -0.16 -0.03 -0.44 0.09 -0.01 -0.38 -0.30 0.24 -0.60 -0.09 0.23 -0.70 -0.16 -1.19
5246 || orf19.3470 || || || Putative flavodoxin; similar to S. cerevisiae Tyw1, an iron-sulfur protein required for synthesis of wybutosine modified tRNA; predicted Kex2p substrate; Spider biofilm induced || 1 -0.13 -0.20 -0.04 0.12 0.12 0.21 -0.24 0.01 -0.35 0.65 -0.48 -0.04 0.05 -0.33 0.09 -0.95
5247 || orf19.5806 || ALD5 || || NAD-aldehyde dehydrogenase; decreased expression in fluconazole-resistant isolate, or in hyphae; biofilm induced; fluconazole-downregulated; protein abundance is affected by URA3 expression in the CAI-4 strain; stationary phase enriched || 1 -0.44 -0.61 -0.40 -0.33 0.18 0.41 -0.36 0.71 0.00 0.59 -1.49 -0.04 -0.06 -0.74 -0.38 -0.90
5248 || orf19.5806 || ALD5 || || NAD-aldehyde dehydrogenase; decreased expression in fluconazole-resistant isolate, or in hyphae; biofilm induced; fluconazole-downregulated; protein abundance is affected by URA3 expression in the CAI-4 strain; stationary phase enriched || 1 -0.67 -0.68 -0.55 -0.53 0.05 0.30 -0.36 0.67 0.03 0.56 -1.36 -0.14 -0.17 -0.63 -0.43 -0.97
5249 || orf19.3626 || || || Ortholog(s) have cytosol, nucleus localization || 1 -0.09 -0.85 -0.94 -0.78 0.45 0.53 0.04 0.43 -0.55 0.59 -0.23 -0.26 0.75 -0.38 0.59 -0.38
5250 || orf19.1305 || || || Ortholog(s) have tRNA (guanine) methyltransferase activity, role in tRNA methylation and mitochondrial matrix, nucleus localization || 1 -0.28 -0.30 -0.51 -0.41 0.17 0.18 -0.06 0.40 -0.26 1.04 0.31 -0.09 -0.18 -0.18 0.26 -0.14
5251 || orf19.6575 || || || Protein of unknown function; rat catheter biofilm repressed || 1 -0.31 -0.82 -0.72 -0.98 -0.12 0.30 -0.23 0.57 -0.61 0.22 0.37 -0.29 0.59 -1.31
5252 || orf19.5064 || MRPL3 || || Ribosomal protein of the large subunit, mitochondrial; repressed in core stress response; protein present in exponential and stationary growth phase yeast cultures || 1 -0.17 -0.69 -0.63 -0.52 -0.20 0.06 0.25 0.44 0.21 0.67 0.16 0.40 0.27 -0.26 0.24 -0.52
5253 || orf19.5167 || IFM1 || || Putative mitochondrial translation initiation factor; transcript regulated by Nrg1, Mig1, and Tup1 || 1 -0.09 -0.45 -0.46 -0.72 0.59 0.13 0.20 0.37 0.58 0.77 -0.11 0.07 0.08 -0.41 0.12 -0.77
5254 || orf19.240 || PAM17 || || Predicted component of the presequence translocase-associated import motor (PAM complex) involved in protein import into mitochondrial matrix || 1 -0.31 -0.33 -0.56 -0.74 0.27 0.10 -0.16 0.51 0.56 0.49 0.29 0.08 0.25 -0.40 -0.18 -0.23
5255 || orf19.4456 || GAP4 || || Putative amino acid permease; hyphal induced; regulated by Hap43, Gcn2 and Gcn4; colony morphology-related gene regulation by Ssnp; detected at plasma membrane of yeast and germ tube by mass spec; Spider biofilm induced || 1 -0.39 -0.49 -0.69 -0.96 -0.12 0.17 0.22 -0.23 0.74 0.48 -0.47 -0.12 -0.13 -0.53 -0.31 -0.68
5256 || orf19.2735 || SEN2 || || Putative tRNA splicing endonuclease subunit; mutation confers hypersensitivity to toxic ergosterol analog and to amphotericin B; 5'-UTR intron; Hap43-induced; Spider biofilm induced || 1 -1.11 -0.91 -0.89 -0.77 -0.18 -0.17 -0.52 -0.67 -0.57 1.20 -0.49 0.20 -0.17 -0.74 -0.00 -2.00
5257 || orf19.2735 || SEN2 || || Putative tRNA splicing endonuclease subunit; mutation confers hypersensitivity to toxic ergosterol analog and to amphotericin B; 5'-UTR intron; Hap43-induced; Spider biofilm induced || 1 -0.52 -0.75 -0.89 -0.97 0.03 0.35 -0.48 -0.48 -0.47 1.34 -0.51 0.35 -0.25 -1.17 -0.05 -1.47
5258 || orf19.2547 || || || Has domain(s) with predicted RNA binding, ribonuclease activity || 1 -0.99 -0.69 -0.99 -1.01 0.16 0.44 -0.41 -0.27 0.01 1.14 -0.25 0.17 -0.22 0.02 -0.79
5259 || orf19.1569 || UTP22 || || Putative U3 snoRNP protein; Ssr1-induced; repressed by prostaglandins; heterozygous null mutant is resistant to parnafungin || 1 -0.46 -0.41 -0.76 -0.69 0.04 -0.15 -0.20 -0.38 -0.56 1.09 -0.34 -0.26 -0.27 -0.14 0.03 -0.50
5260 || orf19.182 || || || Ortholog(s) have rRNA (guanine-N1-)-methyltransferase activity, role in rRNA modification and endoplasmic reticulum, mitochondrion localization || 1 -0.27 -0.37 -0.55 -0.61 0.29 0.47 -0.42 -0.31 -0.51 0.41 -0.43 -0.06 -0.51 -0.19 -0.03 -0.77
5261 || orf19.6297 || || || Ortholog(s) have pseudouridine synthase activity, role in tRNA pseudouridine synthesis and cytosol, nucleus localization || 1 -0.67 -0.74 -0.74 -1.65 -0.30 0.52 -0.40 -0.33 -0.75 0.71 -0.19 -0.28 -0.38 -0.14 -0.05 -0.58
5262 || orf19.6297 || || || Ortholog(s) have pseudouridine synthase activity, role in tRNA pseudouridine synthesis and cytosol, nucleus localization || 1 -0.28 -0.43 -0.93 -1.19 -0.20 0.35 -0.38 -0.09 -0.46 0.55 -0.02 -0.46 -0.00 -0.34 0.08 -0.54
5263 || orf19.6736 || || || Protein required for mitochondrial ribosome small subunit biogenesis; role in maturation of SSU-rRNA; Spider biofilm induced || 1 -0.25 -0.50 -0.79 -1.18 0.14 -0.06 0.22 -0.39 -0.14 0.58 -0.76 -0.50 0.26 -0.61 0.07 -0.79
5264 || orf19.3204 || || || Ortholog of C. dubliniensis CD36 : Cd36_51610, C. parapsilosis CDC317 : CPAR2_303630, Candida tenuis NRRL Y-1498 : CANTEDRAFT_135125 and Debaryomyces hansenii CBS767 : DEHA2E19030g || 1 -0.51 -0.59 -0.40 -0.44 0.47 0.77 -0.28 -0.29 -0.29 0.75 -0.68 -0.15 0.47 -0.71 0.14 -0.69
5265 || orf19.4160 || || || Ortholog(s) have serine-type endopeptidase activity, role in glycoprotein metabolic process, mitochondrial tRNA threonylcarbamoyladenosine modification and mitochondrion localization || 1 -0.50 -0.26 -0.64 -0.55 -0.04 0.76 -0.46 -0.53 0.08 1.01 -0.92 -0.31 0.41 0.02 -0.01 -1.08
5266 || orf19.414 || RSM22 || || Predicted mitochondrial small ribosomal subunit; rat catheter and Spider biofilm induced || 1 -0.28 -0.18 -0.36 -0.69 0.49 0.99 -0.06 -0.49 -0.11 1.14 -0.85 -1.03 0.31 -0.46 -0.38 -1.74
5267 || orf19.6653 || MTG2 || || Putative Obg family GTPase member; peripheral protein of the mitochondrial inner membrane; associates with the large ribosomal subunit; required for mitochondrial translation; rat catheter biofilm repressed || 1 -0.72 -0.50 -0.03 -1.03 0.41 1.05 -0.10 -0.55 -0.26 0.62 -0.51 -0.26 -0.33 -0.76 -0.51 -0.28
5268 || orf19.7593 || || || Putative asparaginase; predicted role in asparagine catabolism; Spider biofilm induced || 1 -0.34 -0.42 -0.47 -0.45 0.28 0.50 -0.02 -0.31 -0.17 0.44 0.14 -0.02 -0.25 -0.56 -1.01 -0.49
5269 || orf19.7593 || || || Putative asparaginase; predicted role in asparagine catabolism; Spider biofilm induced || 1 -0.22 0.01 -0.87 -0.86 0.50 0.53 -0.65 -0.24 -0.01 0.43 0.21 -0.33 -0.52 -0.44 -0.63 -0.85
5270 || orf19.2795 || LHP1 || || Ortholog(s) have tRNA binding activity, role in regulation of ascospore formation, tRNA 3'-trailer cleavage, endonucleolytic and nucleolus, nucleoplasm localization || 1 -0.30 -0.54 -0.65 0.01 -0.14 0.07 -0.42 -0.10 -0.01 0.88 -0.05 -0.08 -0.23 0.02 -0.83 -0.58
5271 || orf19.665 || NEP1 || || Ortholog(s) have rRNA (pseudouridine) methyltransferase activity || 1 -0.19 -0.12 -0.06 -0.02 -0.23 -0.05 -0.23 0.01 0.04 0.98 -0.30 -0.30 -0.14 -0.37 -0.19 -0.59
5272 || orf19.533 || || || Ortholog of Candida albicans WO-1 : CAWG_01778 || 1 -0.49 -0.26 -0.31 -0.13 -0.25 0.11 -0.26 -0.08 0.71 1.16 -0.51 -0.38 -0.10 -0.14 -1.51
5273 || orf19.4410 || ALG1 || || Protein similar to S. cerevisiae Alg1p, a mannosyltransferase involved in N-linked protein glycosylation; likely to be essential for growth, based on an insertional mutagenesis strategy || 1 -0.03 -0.15 -0.25 -0.20 -0.26 -0.19 0.03 -0.06 0.22 0.46 -0.10 0.15 -0.14 0.14 0.09 -0.50
5274 || orf19.5804 || HYU1 || || Putative hydantoin utilization protein A; induced upon adherence to polystyrene; regulated by Gcn2p and Gcn4p || 1 -0.19 -0.32 -0.26 -0.14 0.04 0.10 -0.01 -0.05 0.09 0.25 -0.07 0.03 -0.25 0.03 -0.09 -0.10
5275 || orf19.1831 || || || Dubious open reading frame || 1 -0.63 -0.59 -0.35 0.19 0.05 -0.34 0.66 0.01 0.47 -0.29 -0.07 -0.49
5276 || orf19.2943.5 || || || Ortholog of Candida albicans WO-1 : CAWG_05543 || 1 -0.62 -0.06 -0.13 -0.30 -0.17 -0.07 0.30 0.41 -0.27 0.49 0.02 0.47 0.52 -0.41 -0.05 0.11
5277 || orf19.3209 || FGR42 || || Protein lacking an ortholog in S. cerevisiae; transposon mutation affects filamentous growth || 1 -1.15 -0.30 -0.62 -0.22 0.89 1.19 0.83 0.30 -0.57 -0.77 0.42 0.49 1.03 -0.41 0.42 -0.26
5278 || orf19.635 || || || Protein of unknown function; induced by alpha pheromone in SpiderM medium || 1 -0.82 -0.56 -0.17 -0.59 -0.03 0.58 0.21 -0.14 0.04 -0.17 0.50 0.13 0.76 -0.22 -0.79
5279 || orf19.6575 || || || Protein of unknown function; rat catheter biofilm repressed || 1 0.44 -0.70 0.16 -0.02 0.76 -0.45 -0.29 -0.38 0.10 0.02 -0.31 0.78 -0.16 -0.31
5280 || orf19.644 || HGT9 || || Putative glucose transporter of the major facilitator superfamily; the C. albicans glucose transporter family comprises 20 members; 12 probable membrane-spanning segments; induced at low (0.2%, compared to 2%) glucose in rich media; intron || 1 0.27 -0.43 -0.19 0.56 0.28 0.07 -0.28 -0.66 0.40 0.28 0.74 0.34 0.46 0.01 -0.85
5281 || orf19.3230 || BOI2 || || Putative SH3-domain-containing protein; mutation confers hypersensitivity to toxic ergosterol analog; Spider biofilm induced || 1 0.14 0.21 -0.57 -0.06 0.79 0.19 -0.29 -0.00 -0.21 -0.04 0.10 -0.33 0.57 0.12 0.50 -0.17
5282 || orf19.4872 || || || Protein of unknown function; induced by Mnl1 under weak acid stress; Hap43-induced; mutant is viable || 1 -0.01 0.26 -0.12 0.40 0.82 0.26 -0.07 -0.58 -0.06 0.09 -0.41 -0.16 1.12 0.47 0.30 0.06
5283 || orf19.5212 || || || Ortholog(s) have SUMO ligase activity, role in protein sumoylation, reciprocal meiotic recombination, synaptonemal complex assembly and condensed nuclear chromosome localization || 1 -0.20 0.40 -0.27 -0.25 0.56 0.66 -0.60 -0.64 -0.92 -0.18 -0.00 0.29 1.47 0.58 0.40 -0.37
5284 || orf19.3563 || || || Ortholog of C. dubliniensis CD36 : Cd36_19810, C. parapsilosis CDC317 : CPAR2_206450, Candida tenuis NRRL Y-1498 : CANTEDRAFT_113905 and Debaryomyces hansenii CBS767 : DEHA2C05566g || 1 -0.08 0.25 -0.24 0.10 0.56 0.43 0.19 -0.67 -0.53 -0.54 -0.14 0.34 0.85 0.44 -0.17 -0.13
5285 || orf19.4067 || FGR18 || || Protein lacking an ortholog in S. cerevisiae; transposon mutation affects filamentous growth || 1 0.09 0.28 -0.33 0.54 0.40 -0.36 -0.73 -0.52 -0.04 -0.43 0.50 1.32 0.39 -0.68
5286 || orf19.1311 || SPO75 || || Ortholog(s) have role in ascospore wall assembly || 1 -0.14 0.44 -0.81 0.19 0.33 0.15 -0.66 0.20 0.02 0.50 0.63 0.01
5287 || orf19.3404 || || || Protein of unknown function; transcription repressed by fluphenazine treatment || 1 0.85 -0.68 0.10 0.75 0.26 0.19 0.35 -0.54 -0.95 0.21 0.13 1.16 -0.19 -1.00
5288 || orf19.4377 || KRE1 || || Cell wall glycoprotein; beta glucan synthesis; increases glucan content in S. cerevisiae kre1, complements killer toxin sensitivity; caspofungin induced; Spider/rat catheter/flow model biofilm induced; Bcr1-repressed in RPMI a/a biofilms || 1 0.57 0.42 0.54 0.19 -0.18 0.76 0.16 -0.71 -0.68 -1.87 0.49 1.38 1.86 -0.13 0.45 -0.74
5289 || orf19.747 || NBP35 || || Similar to nucleotide-binding proteins; increased transcription is observed upon benomyl treatment; transcription is induced upon filamentous growth || 1 0.45 0.18 0.19 0.13 0.01 0.06 0.13 -0.28 -0.16 -0.35 -0.04 -0.14 0.30 -0.28 0.10 0.24
5290 || orf19.7304 || || || Protein of unknown function; Hap43-induced; transcript induced early in infection of reconstituted human epithelium, while expression of the C. dubliniensis ortholog is not upregulated; mutants are viable; rat catheter biofilm repressed || 1 1.49 0.76 -0.34 0.96 0.50 -0.05 0.14 0.06 0.37 0.26 -0.37 -0.44 0.25 -0.00 -0.39 -0.64
5291 || orf19.2645 || || || Ortholog of Candida albicans WO-1 : CAWG_04710 || 1 0.54 0.34 -0.85 0.18 -0.11 0.05 -0.04 -0.01 1.08 0.50 -0.27 -0.54 0.52 -0.22 -0.47
5292 || orf19.1270 || FRE3 || || Protein with similarity to ferric reductase Fre10p; possibly an essential gene, disruptants not obtained by UAU1 method || 1 0.03 0.29 -0.55 0.64 -0.40 -0.01 -0.11 0.02 0.83 0.65 -0.25 -0.57 -0.34 -0.09 -0.10 -0.95
5293 || orf19.87 || GPX1 || || Putative thiol peroxidase; rat catheter and Spider biofilm induced || 1 0.41 0.31 -1.02 0.30 -0.09 0.16 0.39 0.04 0.14 0.97 -0.66 -0.34 0.01 -0.51 -0.86
5294 || orf19.3982 || || || Maltase; induced during growth on sucrose; induced by alpha pheromone in SpiderM medium; early-stage flow model biofilm indced || 1 0.59 0.35 -0.63 0.08 0.03 0.37 -0.12 -0.09 0.32 0.61 -0.30 -0.41 -0.42 0.24 0.22 -0.30
5295 || orf19.4856 || LIP3 || || Secreted lipase; gene family member whose members are expressed differentially in response to carbon source and infection; possible role in nutrition and/or in creating an acidic microenvironment; flow model biofilm induced || 1 -0.32 0.36 -1.00 -0.56 0.68 0.42 0.08 -0.23 0.38 -0.21 0.23 -0.73 -0.25 0.01 -0.20 -0.25
5296 || orf19.182 || || || Ortholog(s) have rRNA (guanine-N1-)-methyltransferase activity, role in rRNA modification and endoplasmic reticulum, mitochondrion localization || 1 0.41 -0.23 -1.19 -0.20 0.60 0.44 -0.19 0.08 0.04 0.19 -0.12 -0.16 -0.31 -0.32 0.22 -0.81
5297 || orf19.6148 || || || Homolog of nuclear distribution factor NudE, NUDEL; regulates dynein targeting to microtubule plus ends; flow model biofilm repressed || 1 0.53 0.07 -1.57 -1.24 0.14 -0.54 0.01 0.45 0.18 0.39 -0.37 -0.89 -0.66 -0.75 0.03 -0.56
5298 || orf19.4007 || || || Ortholog(s) have protein-lysine N-methyltransferase activity, role in peptidyl-lysine monomethylation, peptidyl-lysine trimethylation and cytosol, nucleolus localization || 1 0.12 0.12 -0.79 -0.60 -0.08 -0.47 0.12 0.21 0.05 0.12 -0.51 -0.56 -0.49 -0.10 -0.08 -0.56
5299 || orf19.1321 || HWP1 || || Hyphal cell wall protein; host transglutaminase substrate; opaque-, a-specific, alpha-factor induced; at MTLa side of conjugation tube; virulence complicated by URA3 effects; Bcr1-repressed in RPMI a/a biofilms; Spider biofilm induced || 1 -0.03 -0.19 -1.57 -0.84 -0.20 -1.28 0.81 -0.42 1.02 0.65 -0.75 -1.81 0.20 -1.29 -0.47 -1.01
5300 || orf19.6148 || || || Homolog of nuclear distribution factor NudE, NUDEL; regulates dynein targeting to microtubule plus ends; flow model biofilm repressed || 1 0.15 0.19 -0.81 -0.48 -0.05 -0.44 0.35 -0.24 0.80 0.58 0.11 -1.00 -0.51 -0.56 -0.49 -0.83
5301 || orf19.7534 || MIS12 || || Mitochondrial C1-tetrahydrofolate synthase precursor || 1 -0.01 -0.04 -0.63 -0.24 0.12 -0.46 0.25 0.08 0.45 -0.16 -0.27 -0.73 -0.19 0.14 -0.09 -0.19
5302 || orf19.7164 || || || Ortholog(s) have role in ascospore formation, conidiophore development, conidium formation, response to oxidative stress, sporocarp development involved in sexual reproduction, vacuolar protein processing || 1 0.25 0.17 -0.73 0.02 0.04 0.14 -0.02 -0.40 -0.47 -0.26 -0.29 -0.35 -0.07 -0.01 0.11 -0.49
5303 || orf19.1841 || || || Protein of unknown function; Hap43-induced gene || 1 -0.00 0.10 -0.94 0.00 0.08 -0.06 -0.19 -0.83 -0.38 -0.16 -0.17 -0.09 0.36 -0.14 -0.55 -0.46
5304 || orf19.4819 || || || Protein of unknown function; transcript detected on high-resolution tiling arrays; rat catheter biofilm induced || 1 -0.80 -0.40 -1.06 0.26 -0.09 -0.88 -0.03 -1.00 0.64 -0.17 -0.60 -0.68 0.43 0.27 -0.05 -0.98
5305 || orf19.5962 || HGT4 || || Glucose and galactose sensor; fermentation, filamentation, virulence roles; 20-member glucose transporter family; extended C terminus; high-glucose repressed; macrophage induced; flow model biofilm repressed; Spider biofilm induced || 1 -0.16 -0.22 -0.26 0.18 0.49 -0.10 -0.20 -0.29 -0.09 0.22 -0.23 -0.12 0.26 0.22 0.12 -0.34
5306 || orf19.4321 || || || Ortholog of Candida albicans WO-1 : CAWG_04677 || 1 -0.08 -0.17 -1.06 0.20 -0.28 -0.41 0.46 -0.34 0.03 -0.25 0.76 -0.58 -0.37 0.12 -0.25
5307 || orf19.5234 || RBD1 || || Rhomboid-like protein; similar to putative intramembrane serine proteases; role in filamentous growth; Gcn4-regulated; caspofungin repressed; Spider biofilm induced || 1 0.69 -0.32 -0.05 -0.33 -0.17 -0.51 0.02 0.32 -0.11 -0.23 0.47 -0.45 -0.03 -0.09 -0.60 0.06
5308 || orf19.937 || || || Ortholog of Candida albicans WO-1 : CAWG_04446 || 1 0.90 -0.67 -0.05 -0.18 0.42 -1.09 -0.54 0.31 -0.07 -0.32 -0.07 0.15 -0.04 1.03 -0.36 -0.25
5309 || orf19.4814 || || || Ortholog of C. dubliniensis CD36 : Cd36_08960, C. parapsilosis CDC317 : CPAR2_301680, Candida tenuis NRRL Y-1498 : cten_CGOB_00021 and Debaryomyces hansenii CBS767 : DEHA2F11088g || 1 1.24 -0.63 0.66 -0.91 -0.11 -1.06 -0.22 0.59 -0.87 -0.69 -0.25 -0.40 -0.37 0.39 -0.11 0.30
5310 || orf19.5831 || || || Ortholog of C. parapsilosis CDC317 : CPAR2_212260, C. dubliniensis CD36 : Cd36_17620, Candida orthopsilosis Co 90-125 : CORT_0A11590 and Candida tropicalis MYA-3404 : CTRG_01348 || 1 0.69 -0.17 0.22 -0.39 0.32 -0.21 -0.14 0.74 -0.56 -1.31 0.03 -0.38 -0.14 0.51 0.65 0.23
5311 || orf19.1116 || || || Protein of unknown function; planktonic growth-induced gene || 1 0.16 0.26 0.28 0.06 0.10 0.04 0.14 0.10 -0.33 -0.34 0.59 0.07 -0.06 0.22 -0.22 0.65
5312 || orf19.980 || || || Ortholog(s) have inositol heptakisphosphate kinase activity, inositol hexakisphosphate 1-kinase activity, inositol hexakisphosphate 3-kinase activity, inositol hexakisphosphate 4-kinase activity, inositol hexakisphosphate 6-kinase activity || 1 0.19 0.16 -0.12 0.06 -0.05 0.06 0.22 0.14 0.08 -0.45 0.17 0.22 0.17 0.48 -0.08 0.28
5313 || orf19.4624 || HRT2 || || Protein described as having a role in Ty3 transposition; repressed in hyphae; stationary phase enriched protein; rat catheter and Spider biofilm repressed || 1 0.66 0.39 -0.25 -0.10 -0.40 -0.34 0.29 0.57 -0.48 -0.94 0.58 0.15 0.04 0.18 -0.73 0.40
5314 || orf19.1889 || || || Putative phosphoglycerate mutase family protein; stationary phase enriched protein; early-stage flow model biofilm induced; Spider biofilm repressed || 1 0.49 0.46 -0.13 0.06 -0.14 -0.44 0.17 0.21 0.10 -0.77 0.76 0.43 0.42 0.58 -0.81 0.36
5315 || orf19.1889 || || || Putative phosphoglycerate mutase family protein; stationary phase enriched protein; early-stage flow model biofilm induced; Spider biofilm repressed || 1 0.24 0.10 -0.02 0.18 -0.14 -0.47 -0.28 -0.08 0.10 -0.64 0.30 0.21 0.22 0.38 -0.37 0.26
5316 || orf19.2107 || MUQ1 || || Putative choline phosphate cytidylyltransferase/phosphoethanolamine cytidylyltransferase; repressed in hyphae compared vs yeast; Hap43-repressed; flow model biofilm induced; Spider biofilm repressed || 1 0.76 0.80 0.10 0.19 -0.21 -0.57 0.12 0.15 -0.14 -0.55 0.65 0.14 -0.34 -0.56 -1.37 0.36
5317 || orf19.2107 || MUQ1 || || Putative choline phosphate cytidylyltransferase/phosphoethanolamine cytidylyltransferase; repressed in hyphae compared vs yeast; Hap43-repressed; flow model biofilm induced; Spider biofilm repressed || 1 1.00 0.91 0.28 0.31 -0.06 -0.34 0.55 0.37 0.24 -0.17 0.90 0.74 -0.34 0.19 -0.92 0.64
5318 || orf19.5519 || GCV1 || || Putative T subunit of glycine decarboxylase; transcript negatively regulated by Sfu1; Spider biofilm repressed || 1 1.16 1.37 -0.40 -0.00 -0.59 -1.18 0.19 0.45 -0.14 -0.50 0.62 0.96 -0.40 -0.08 -0.14 0.18
5319 || orf19.2600 || SPC98 || || Putative component of the microtubule-nucleating Tub4p (gamma-tubulin) complex; periodic mRNA expression, peak at cell-cycle S/G2 phase || 1 -0.37 1.01 -0.24 -0.06 -0.09 -0.63 -0.25 0.10 -0.14 0.10 0.15 0.63 0.12 0.26 -0.56 0.24
5320 || orf19.1626 || || || Deoxyhypusine synthase; catalyzes formation of deoxyhypusine, the first step in hypusine biosynthesis; Spider biofilm repressed || 1 0.02 0.28 -0.59 -0.34 0.10 -0.85 -0.13 0.52 -0.11 0.60 0.39 0.12 0.24 0.36 -0.96 0.15
5321 || orf19.7059 || || || Ortholog(s) have endoribonuclease activity, role in nuclear mRNA surveillance of mRNP export, transcription, DNA-templated and cytoplasm, nucleus localization || 1 -0.06 0.90 -0.53 -0.49 0.13 -1.14 -0.01 0.11 0.08 0.10 -0.08 -0.44 -0.48 0.63 -0.68 -0.25
5322 || orf19.6008.3 || || || Ortholog of C. dubliniensis CD36 : Cd36_00920, Debaryomyces hansenii CBS767 : DEHA2F20724g, Pichia stipitis Pignal : PICST_32745 and Candida albicans WO-1 : CAWG_01277 || 1 -0.75 1.16 -0.47 -0.35 -0.15 -0.38 -0.38 -0.28 -0.08 -0.46 -0.32 -0.43 -0.46 0.15 -0.52 0.05
5323 || orf19.3728 || || || Ortholog(s) have protein phosphatase 1 binding, protein phosphatase type 1 regulator activity, role in chromosome segregation, regulation of phosphoprotein phosphatase activity and cytoplasm localization || 1 -0.68 1.24 0.07 -1.17 0.41 -0.26 0.25 -0.81 -0.18 -0.44 -0.89 0.39 0.33 -1.13
5324 || orf19.5335 || SGS1 || || RecQ-related DNA helicase; Bloom's syndrome-related gene; haploinsufficient for wild-type lifespan; upregulated in farnesol treated biofilm || 1 0.48 0.38 0.22 -0.02 0.44 -0.46 -0.08 0.50 0.05 0.16 -0.18 -0.54 0.21 0.28 -1.25 -0.08
5325 || orf19.420 || || || Protein of unknown function || 1 0.13 0.17 0.16 -1.09 -0.45 -0.24 -0.34 0.01 -0.39 0.43 -0.16 -0.41 -0.04 -0.90
5326 || orf19.5597 || POL5 || || Putative DNA Polymerase phi; F-12/CO2 early biofilm induced || 1 0.56 0.79 0.07 -0.14 0.46 0.57 -0.42 -0.10 -0.58 0.68 -0.05 -0.07 -0.12 -0.39 -0.42 0.46
5327 || orf19.5597 || POL5 || || Putative DNA Polymerase phi; F-12/CO2 early biofilm induced || 1 0.66 0.54 0.30 0.08 0.32 0.57 -0.31 -0.16 -0.30 0.63 0.09 -0.09 0.01 0.16 -0.33 0.42
5328 || orf19.1720 || || || Ortholog(s) have role in mitotic recombination || 1 0.82 0.72 0.47 0.69 0.01 -0.48 -0.50 -0.09 -0.37 1.33 -0.10 0.07 -0.56 0.36 -0.70 0.11
5329 || orf19.3904 || MRV4 || || Protein of unknown function; Spider biofilm induced || 1 1.14 0.50 0.73 0.04 -0.80 0.35 -0.68 0.59 -0.67 0.15 -0.98 0.07 -1.07 1.06
5330 || orf19.5555 || || || Ortholog of C. dubliniensis CD36 : Cd36_63300, Candida tropicalis MYA-3404 : CTRG_05769 and Candida albicans WO-1 : CAWG_05077 || 1 0.45 0.58 0.01 0.36 -0.08 0.22 -0.42 0.11 -0.32 -0.11 -0.03 -0.09 -0.28 0.42 -0.72 0.27
5331 || orf19.2974 || YKT6 || || Putative protein of the vacuolar SNARE complex; predicted role in vacuolar fusion; rat catheter biofilm repressed || 1 0.67 0.66 -0.09 -0.23 -0.24 -0.50 -0.12 0.27 -0.62 0.18 0.18 -0.32 -0.26 0.15 -0.24 0.03
5332 || orf19.2974 || YKT6 || || Putative protein of the vacuolar SNARE complex; predicted role in vacuolar fusion; rat catheter biofilm repressed || 1 0.90 0.64 0.36 0.08 -0.07 -0.52 -0.11 0.30 -0.56 0.20 0.28 -0.14 -0.25 -0.26 -0.13 0.13
5333 || orf19.1476 || || || Ortholog(s) have mRNA (N6-adenosine)-methyltransferase activity, role in mRNA methylation, meiosis, negative regulation of pseudohyphal growth and MIS complex localization || 1 0.93 0.92 0.28 0.11 0.29 -1.00 0.01 0.18 -0.39 1.35 -0.47 -0.40 0.49 0.32 0.30
5334 || orf19.5340 || || || Putative Rab GTPase activator; role in ER to Golgi vesicle-mediated transport; Spider biofilm induced || 1 0.54 0.47 0.27 0.02 0.23 -0.41 -0.10 0.00 0.00 0.78 0.35 -0.20 0.00 0.64 0.17 0.53
5335 || orf19.474 || || || Ortholog(s) have role in mRNA export from nucleus, nuclear envelope organization, protein export from nucleus and endoplasmic reticulum, nuclear envelope localization || 1 -0.11 -0.10 -0.10 0.15 0.00 -0.33 -0.37 -0.07 -0.12 -0.15 0.28 0.25 0.21 0.02 0.60 -0.08
5336 || orf19.4278 || || || Ortholog(s) have methylated histone residue binding activity and role in negative regulation of transcription from RNA polymerase II promoter || 1 0.03 -0.35 -0.07 -0.16 -0.68 -0.12 -0.11 0.11 -0.15 -0.27 0.16 0.14 0.53 0.31 0.63 0.19
5337 || orf19.5976 || || || Protein of unknown function; ortholog of S. cerevisiae Urn1; downregulated by fluphenazine treatment, in azole-resistant strains that overexpress CDR1 and CDR2 or MDR1 || 1 -0.34 -0.40 0.27 0.01 -0.07 0.21 0.25 -0.25 -0.06 -0.20 -0.34 -0.05 0.34 0.52 0.54 0.15
5338 || orf19.5717 || || || Ortholog of Candida albicans WO-1 : CAWG_05019 || 1 -1.27 0.26 0.27 0.96 -0.41 0.28 -0.62 -1.23 0.61 -0.16 -0.22 -0.07 0.13 0.07
5339 || orf19.10711 || PIKALPHA || || Putative phosphatidylinositol kinase; non-sex gene located within the MTLalpha mating-type-like locus || 1 0.93 0.64 -0.65 1.60 -0.33 -1.09 0.66 -0.09 -0.16 0.92 0.95 0.96 2.00 0.43
5340 || orf19.6339 || NRG2 || || Transcription factor; transposon mutation affects filamentous growth || 1 0.16 0.14 0.35 1.68 -0.31 0.46 -0.25 -0.90 -0.22 0.67 0.73 0.12 2.37 -0.16 -0.98
5341 || orf19.7457 || || || Protein with Mob2p-dependent hyphal regulation || 1 0.11 0.16 0.48 0.69 -0.09 -0.22 0.05 0.17 -0.01 -0.24 0.09 0.44 0.36 0.85 0.23 -0.14
5342 || orf19.5773 || || || Putative dipeptidyl-peptidase III; protein detected by mass spec in exponential and stationary phase cultures; Hog1p-induced; clade-associated gene expression || 1 -0.20 -0.20 0.16 -0.08 -0.21 -0.13 0.06 0.13 0.19 -0.27 -0.04 0.22 -0.01 0.70 0.03 0.11
5343 || orf19.2962 || || || Protein of unknown function; Spider biofilm induced || 1 -1.10 -0.78 0.04 -0.85 -0.77 1.48 0.39 -1.01 -0.60 -0.27 -0.93 1.37 1.14 4.78 1.24 -0.89
5344 || orf19.6390 || || || Protein of unknown function; Spider biofilm induced || 1 -0.26 -1.05 -0.36 -0.76 -0.16 0.05 -0.41 -0.25 -0.06 1.05 0.53 4.19 0.27 0.16
5345 || orf19.4366 || || || Ortholog of C. dubliniensis CD36 : Cd36_28870, Candida tropicalis MYA-3404 : CTRG_00731 and Candida albicans WO-1 : CAWG_01703 || 1 -0.34 0.31 -0.73 -0.04 0.05 -1.12 -0.35 0.22 -0.31 -0.33 0.37 4.07 0.03 -0.10
5346 || orf19.3284 || || || Ortholog of Candida albicans WO-1 : CAWG_01431 || 1 -0.58 -0.33 -0.85 0.65 -1.21 0.27 -0.88 -0.11 -1.67 0.19 0.03 -0.40 -0.20 5.31 -0.69
5347 || orf19.4936 || || || Dubious open reading frame || 1 -0.72 0.05 0.33 0.51 -0.68 0.11 0.34 -0.28 -0.06 -0.07 1.41 0.25
5348 || orf19.6307 || || || Ortholog of C. dubliniensis CD36 : Cd36_30250, Candida tenuis NRRL Y-1498 : CANTEDRAFT_98619, Debaryomyces hansenii CBS767 : DEHA2G22594g and Pichia stipitis Pignal : PICST_50168 || 1 0.48 0.81 0.61 -2.02 -0.14 1.18 -0.04 -0.11 0.12 -0.83 -0.20 3.57 -0.20 0.28
5349 || orf19.7055 || || || Dubious open reading frame || 1 -0.14 0.14 -0.32 0.39 0.67 0.50 0.09 0.02 -0.80 -0.29 2.22 0.16 0.61
5350 || orf19.4200 || || || Ortholog of Candida albicans WO-1 : CAWG_05300 || 1 -0.15 -0.17 1.02 0.94 -0.14 0.14 0.39 0.57 0.14 -0.72 4.26 -0.14
5351 || orf19.2907 || PGA42 || || Putative GPI-anchored adhesin-like protein; decreased transcription is observed in azole-resistant strains that overexpress CDR1 and CDR2 or MDR1 || 1 0.30 0.62 1.20 0.69 0.13 -0.32 1.27 0.19 0.25 0.13 0.64 4.01 -0.09
5352 || orf19.4151 || SPO1 || || Protein similar to phospholipase B; fungal-specific (no human or murine homolog) || 1 -0.05 1.58 0.37 0.84 0.30 -0.36 -0.64 0.06 0.68 0.23 0.68 0.54 4.84 0.69
5353 || orf19.1476 || || || Ortholog(s) have mRNA (N6-adenosine)-methyltransferase activity, role in mRNA methylation, meiosis, negative regulation of pseudohyphal growth and MIS complex localization || 1 0.42 0.11 -0.71 0.14 0.63 -0.03 -0.13 0.08 0.36 0.67 -0.14 -0.43 2.03 -0.33 0.18
5354 || orf19.2312 || || || Protein similar to ferric reductase Fre10p; possibly an essential gene, disruptants not obtained by UAU1 method || 1 -0.08 -0.01 -0.40 0.66 -0.83 -0.36 0.48 -0.06 0.31 -0.62 2.08 -0.61
5355 || orf19.1871 || || || Ortholog(s) have structural molecule activity, role in histone exchange and Swr1 complex, cytosol localization || 1 0.01 -0.07 -0.07 -0.12 -0.17 -0.21 -0.17 0.10 0.15 0.09 -0.03 0.18 -0.08 0.41 -0.32 0.03
5356 || orf19.6012 || || || Ortholog(s) have cell division site, cell tip, cytosol localization || 1 0.20 0.20 0.16 0.06 -0.05 -0.25 0.08 0.03 -0.08 0.32 -0.22 0.18 0.01 0.77 -0.60 0.12
5357 || orf19.2539 || || || Protein of unknown function; transcript detected on high-resolution tiling arrays || 1 0.22 0.10 0.41 0.30 -0.55 -0.83 -0.17 -0.42 -0.87 -0.07 0.48 -0.39 -0.09 1.89 -0.24 1.58
5358 || orf19.450 || || || Protein of unknown function || 1 -0.49 0.02 -0.55 -0.39 -1.23 -0.63 -1.07 -0.22 0.92 -0.60 -0.50 2.79 0.32 0.50
5359 || orf19.1824 || PGA50 || || Putative GPI-anchored protein; adhesin-like protein || 1 -0.35 -0.38 0.08 -0.09 0.20 -0.72 -0.35 -0.53 -0.16 -0.31 1.12 -0.03 1.02 0.09
5360 || orf19.5616 || || || Ortholog of C. dubliniensis CD36 : Cd36_63740, C. parapsilosis CDC317 : CPAR2_503850, Pichia stipitis Pignal : PICST_32045 and Candida guilliermondii ATCC 6260 : PGUG_00070 || 1 0.08 0.21 0.08 -0.33 -0.21 -0.46 0.23 -0.10 -0.02 0.16 -0.84 -0.49 -0.73 2.03 -0.62 -2.05
5361 || orf19.4404 || PGA49 || || Putative GPI-anchored protein || 1 0.30 0.68 -0.10 -0.67 0.16 -1.08 -0.49 -0.48 -0.06 -0.09 -0.62 -0.02 -0.08 2.11 -0.44 -0.77
5362 || orf19.1418 || SEC15 || || Predicted exocyst subunit; cellular bud tip-associated protein; ortholog of S. cerevisiae SEC15 || 1 -0.03 0.10 -0.23 -0.38 -0.24 -0.53 -0.11 -0.31 0.16 0.40 -0.28 -0.13 -0.06 0.46 -0.05 -0.34
5363 || orf19.6179 || || || Ortholog of Candida albicans WO-1 : CAWG_03090 || 1 -0.15 -0.78 0.31 -0.02 -0.55 -0.93 -0.35 -0.43 -1.14 -0.37 -0.66 -0.12 -0.26 1.08 -0.61 -0.24
5364 || orf19.1737 || || || Ortholog of Candida albicans WO-1 : CAWG_01802 || 1 -0.33 -0.16 0.10 -0.51 -0.27 -1.55 -0.17 -0.42 -1.30 0.13 -0.33 -0.23 0.19 1.35 -1.26 -0.08
5365 || orf19.3522 || || || Protein of unknown function; flow model biofilm induced; transcript repressed by ciclopirox olamine || 1 -0.68 -0.28 0.05 -0.48 -1.43 -0.23 -0.61 -0.57 -2.95 0.16 -1.10 -0.13 1.43 1.67 -1.34
5366 || orf19.4151 || SPO1 || || Protein similar to phospholipase B; fungal-specific (no human or murine homolog) || 1 0.92 -0.06 0.55 -0.25 -2.03 0.14 -0.19 -1.90 0.08 0.43 0.23 0.27 -1.13
5367 || orf19.6670 || CAC2 || || Component of the chromatin assembly factor I (CAF-1); involved in regulation of white-opaque switching frequency; macrophage-induced || 1 0.03 0.22 0.18 -0.19 -0.55 -0.07 -0.32 -0.31 -0.31 0.28 0.14 0.37 0.04 0.24 -0.68 0.09
5368 || orf19.1060 || || || Ortholog of Candida albicans WO-1 : CAWG_00968 || 1 0.69 0.56 0.13 0.82 -0.88 -0.29 -0.03 -0.02 -0.29 -0.00 -0.02 0.11 -0.10 0.31 -0.15 0.25
5369 || orf19.216 || || || Protein with a metallo-dependent phosphatase domain; ketoconazole-induced; upregulation correlates with clinical development of fluconazole resistance || 1 0.47 0.46 0.26 0.63 -0.18 -0.23 0.33 -0.36 -0.24 0.03 -0.12 0.06 -0.10 0.37 -0.06 0.17
5370 || orf19.7348 || || || Ortholog of Candida albicans WO-1 : CAWG_02878 || 1 0.67 1.10 0.51 -0.35 -0.24 -0.70 0.28 -0.63 -0.28 0.23 0.30 -0.05 -0.19
5371 || orf19.4804 || LIP2 || || Secreted lipase; member of a differentially expressed lipase gene family; expressed in alimentary tract, but not oral tissue, during mouse oral infection; may have a role in nutrition and/or in creating an acidic microenvironment || 1 0.97 0.98 0.52 -0.76 -0.23 -0.79 -0.55 -0.33 0.19 -0.04 -0.32 0.43
5372 || orf19.2825 || DRE2 || || Putative cytosolic Fe-S protein assembly protein; a-specific transcript; regulated by Sef1, Sfu1, and Hap43; rat catheter and Spider biofilm induced || 1 0.84 0.66 0.40 0.03 -0.60 -0.21 -0.15 -0.60 -0.72 -0.64 -0.52 0.44 -0.08 -0.19 0.22 0.35
5373 || orf19.6501 || || || Ortholog of C. dubliniensis CD36 : Cd36_71960, Pichia stipitis Pignal : psti_CGOB_00136, Spathaspora passalidarum NRRL Y-27907 : SPAPADRAFT_63786 and Candida tropicalis MYA-3404 : CTRG_05049 || 1 0.73 0.46 0.44 0.29 -1.22 -1.21 0.03 -0.67 -1.35 -1.07 -0.20 1.34 0.45 0.89 0.45 0.99
5374 || orf19.6501 || || || Ortholog of C. dubliniensis CD36 : Cd36_71960, Pichia stipitis Pignal : psti_CGOB_00136, Spathaspora passalidarum NRRL Y-27907 : SPAPADRAFT_63786 and Candida tropicalis MYA-3404 : CTRG_05049 || 1 0.54 0.31 0.47 0.66 -0.95 0.12 -0.20 -0.80 -0.68 -0.82 0.41 0.73 0.38 0.73 0.44 1.16
5375 || orf19.6791 || HHT1 || || Putative histone H3; reduced mRNA abundance in fkh2 mutant; farnesol regulated; Spider biofilm induced; rat catheter biofilm repressed || 1 0.31 0.23 -0.40 -0.30 -0.10 -0.22 -0.40 0.35 0.20 0.54 0.65 0.40
5376 || orf19.4227 || || || Ortholog of C. parapsilosis CDC317 : CPAR2_100400, C. dubliniensis CD36 : Cd36_52020, Debaryomyces hansenii CBS767 : DEHA2F14278g and Candida orthopsilosis Co 90-125 : CORT_0F00500 || 1 0.58 0.00 0.36 -0.10 -0.13 0.03 -0.12 -0.43 -0.47 -0.06 -0.03 1.00 0.08 0.52 -0.02 0.12
5377 || orf19.5233 || || || Ortholog of Candida albicans WO-1 : CAWG_00211 || 1 0.01 0.04 0.49 0.13 -0.37 -0.39 -0.53 -0.12 0.22 0.21 0.36 0.43 -0.05 -0.15
5378 || orf19.6921 || || || Ortholog(s) have RNA polymerase I upstream control element sequence-specific DNA binding transcription factor activity and role in chromatin organization, transcription of nuclear large rRNA transcript from RNA polymerase I promoter || 1 0.62 0.26 0.71 0.01 0.09 0.01 -0.15 -0.29 -0.56 -0.11 0.11 -0.20 0.10 0.73 -0.59 0.59
5379 || orf19.1530 || || || Protein of unknown function || 1 0.81 0.64 0.70 1.35 0.50 0.40 0.12 -0.05 -2.47 -0.17 0.59 0.63 1.49 0.87 1.05
5380 || orf19.7192 || || || Ortholog of Candida albicans WO-1 : CAWG_05720 || 1 0.03 0.35 0.28 -0.32 0.12 -0.17 -1.77 -0.45 0.55 0.53 2.56 0.16 0.47
5381 || orf19.4196 || || || Dubious open reading frame || 1 0.29 0.20 0.49 -0.22 -0.21 0.39 0.69 -0.01 -2.33 -0.71 0.94 -0.23 0.64 0.94 -0.10 0.41
5382 || orf19.7198 || || || CCR4-NOT complex component; involved in controlling mRNA initiation, elongation and degradation; rat catheter biofilm induced || 1 -0.31 -0.31 0.02 -0.16 -0.20 -0.05 -0.41 -0.03 -0.19 -0.32 0.49 0.12 0.31 0.43 -0.06 0.32
5383 || orf19.2037 || || || Ortholog of C. dubliniensis CD36 : Cd36_15810, C. parapsilosis CDC317 : CPAR2_212950, Candida tenuis NRRL Y-1498 : CANTEDRAFT_116162 and Debaryomyces hansenii CBS767 : DEHA2D18392g || 1 -0.20 -0.06 0.17 0.00 -0.12 -0.11 -0.11 0.02 -0.20 -0.54 0.26 0.05 0.29 0.16 0.11 0.07
5384 || orf19.2671 || || || Protein with a predicted FAD-dependent pyridine nucleotide reductase domains; putative oxidoreductase; Plc1-regulated; possibly an essential gene, disruptants not obtained by UAU1 method || 1 -0.23 -0.33 0.66 0.39 -0.39 -0.12 -0.39 -0.24 -0.63 -1.15 0.16 0.09 0.31 0.46 -0.12 0.69
5385 || orf19.3362 || || || Has domain(s) with predicted flavin adenine dinucleotide binding, oxidoreductase activity and role in oxidation-reduction process || 1 -0.33 -0.28 -0.15 -0.23 -0.49 -0.61 -0.34 -0.56 -0.90 -2.08 0.27 0.38 0.09 0.95 0.11 1.05
5386 || orf19.4905 || || || Putative MFS transporter; Hap43p-induced gene; also regulated by regulated by Sef1p and Sfu1p; repressed in a ssr1 null mutant || 1 -0.35 -0.32 0.16 -0.59 -0.38 -0.26 -0.26 -0.50 0.17 -0.98 -0.18 -0.15 0.21 0.95 -0.52 0.77
5387 || orf19.795 || VPS36 || || ESCRT II protein sorting complex subunit; involved in Rim8 processing and proteolytic activation of Rim101, which regulates pH response; role in uptake of Histatin-5 into vacuole || 1 -0.09 0.15 0.03 0.09 0.06 -0.13 -0.18 -0.12 0.16 -0.54 0.05 0.22 0.27 0.50 -0.15 0.24
5388 || orf19.2910 || PGA43 || || Putative GPI-anchored protein || 1 0.28 0.71 0.08 0.03 -0.52 -0.37 -0.01 0.39 0.66 0.03 -0.32 0.01 0.60 0.09 -0.47 -0.13
5389 || orf19.3336 || || || Ortholog of Candida albicans WO-1 : CAWG_01228 || 1 0.28 0.38 1.09 0.04 -0.66 0.40 -0.28 1.43 1.26 -0.09 -0.28 -0.27 1.57 0.37 -0.10 0.38
5390 || orf19.4571 || || || CoA-transferase family protein; rat catheter biofilm repressed || 1 0.20 1.53 0.66 0.40 0.10 0.27 0.25 0.38 0.68 -0.25 0.08 -0.43 1.25 0.27 -0.08 0.02
5391 || orf19.2866 || || || Has domain(s) with predicted DNA binding activity || 1 0.02 0.44 0.01 0.05 -0.02 0.34 0.33 0.10 0.68 -0.32 -0.07 -0.01 0.82 0.23 -0.45 0.01
5392 || orf19.1910 || || || Predicted NADH-dependent flavin oxidoreductase; Hap43-repressed gene || 1 -0.24 0.14 0.33 -0.19 -0.07 0.05 -0.08 0.05 0.38 0.03 -0.44 -0.35 0.44 0.50 -0.57 -0.03
5393 || orf19.5661 || PTC7 || || Protein phosphatase, type 2C; has S/T phosphatase activity, Mn2+/Mg2+ dependent; predicted membrane-spanning segment and mitochondrion-targeting signal || 1 -0.18 0.07 0.18 -0.09 0.08 -0.06 -0.00 0.07 0.34 -0.05 -0.21 0.03 0.29 0.19 -0.18 -0.13
5394 || orf19.4549 || FGR38 || || Protein lacking an ortholog in S. cerevisiae; member of a family of related proteins; transposon mutation affects filamentous growth; macrophage-induced gene; Hap43p-repressed gene || 1 -0.24 -0.05 0.49 -0.03 -0.17 -0.06 0.12 0.03 0.64 -0.17 -0.25 0.06 0.28 0.33 -0.23 0.08
5395 || orf19.1195 || || || Ortholog(s) have metalloendopeptidase activity, role in cellular iron ion homeostasis, protein processing involved in protein targeting to mitochondrion and mitochondrion localization || 1 -0.17 -0.04 0.29 0.03 0.11 0.06 -0.03 0.01 0.46 0.04 -0.02 0.10 0.26 -0.11 -0.41 -0.01
5396 || orf19.1515 || CHT4 || || Chitinase; similar to S. cerevisiae sporulation-specific Cts2p; functionally complements A. gossypii cts2 mutant sporulation defect; homozygous null mutation causes no obvious defects; transcription decreases upon yeast-to-hyphal switch || 1 -0.01 0.18 0.34 0.07 0.37 -0.12 0.15 -0.08 0.97 0.15 -0.19 -0.14 0.19 -0.01 -0.34 0.05
5397 || orf19.3325 || || || Putative glycogen synthesis initiator; regulated by Efg1 and Efh1; Hog1-repressed; colony morphology-related gene regulation by Ssn6; induced by prostaglandins; flow model biofilm induced || 1 -0.16 0.03 0.49 -0.02 0.12 0.60 0.67 0.27 0.70 -0.25 -0.25 0.14 1.09 0.31 0.33 0.75
5398 || orf19.5625 || || || Ortholog of C. dubliniensis CD36 : Cd36_63640, Pichia stipitis Pignal : PICST_32878, Candida guilliermondii ATCC 6260 : PGUG_03423 and Candida tropicalis MYA-3404 : CTRG_02106 || 1 0.24 0.59 0.39 0.28 0.00 1.30 0.65 -0.04 1.29 -0.96 -0.60 -0.09 2.36 1.01 1.00 0.19
5399 || orf19.846 || || || Predicted protein kinase similar to S. cerevisiae Nnk1; implicated in proteasome function in S. cerevisiae; induced by Mnl1 under weak acid stress || 1 0.29 0.51 0.50 -0.10 0.43 0.44 0.19 0.00 0.81 -0.39 -1.06 -0.46 1.14 0.64 0.28 0.33
5400 || orf19.846 || || || Predicted protein kinase similar to S. cerevisiae Nnk1; implicated in proteasome function in S. cerevisiae; induced by Mnl1 under weak acid stress || 1 0.09 0.09 0.30 -0.26 0.08 0.39 0.04 -0.15 0.65 -0.56 -1.00 -0.43 0.71 0.54 0.08 0.10
5401 || orf19.5625 || || || Ortholog of C. dubliniensis CD36 : Cd36_63640, Pichia stipitis Pignal : PICST_32878, Candida guilliermondii ATCC 6260 : PGUG_03423 and Candida tropicalis MYA-3404 : CTRG_02106 || 1 -0.30 0.00 -0.16 0.04 -0.85 0.88 0.31 -0.09 0.32 -1.05 -0.99 -0.54 1.91 0.28 0.90 0.61
5402 || orf19.5286 || YCP4 || || Putative flavodoxin; flow model, rat catheter and Spider biofilm repressed || 1 -0.20 -0.22 0.25 0.30 -0.05 0.64 0.26 0.02 0.26 -0.49 -0.37 -0.35 0.50 0.11 0.28 -0.46
5403 || orf19.2797 || || || Has domain(s) with predicted ATP binding, DNA binding, helicase activity || 1 -0.20 -0.08 0.11 0.27 0.31 -0.03 -0.16 -0.19 0.49 -0.41 -0.49 -0.27 0.22 0.02 -0.02 0.04
5404 || orf19.5918 || || || Ortholog of Candida albicans WO-1 : CAWG_02773 || 1 -1.70 0.12 0.80 1.10 0.06 -0.16 0.71 2.55 -1.30 -1.06 0.24 0.29 -0.89 -1.67
5405 || orf19.1351 || || || Ortholog of C. parapsilosis CDC317 : CPAR2_407000, C. dubliniensis CD36 : Cd36_22440, Candida tenuis NRRL Y-1498 : cten_CGOB_00049 and Lodderomyces elongisporus NRLL YB-4239 : LELG_02401 || 1 -0.76 -0.33 0.30 -0.47 -0.01 0.12 2.00 -0.93 0.43 -0.18 0.33 0.63 -0.33 -0.30
5406 || orf19.2910 || PGA43 || || Putative GPI-anchored protein || 1 -0.33 -0.17 0.00 -0.00 0.06 -0.15 -0.21 0.35 0.70 -0.10 -0.03 -0.26 0.12 0.29 0.03 -0.17
5407 || orf19.10712 || MTLALPHA1 || || Master regulator (activator) of alpha mating type; gene of the MTLalpha (Mating Type Like) locus; ortholog of S. cerevisiae Alpha1p; a/alpha mating type may increase virulence, offers competitive advantage || 1 1.38 -0.59 0.88 -0.38 1.90 -0.58 0.22 0.22 0.35 2.03 4.01 0.26
5408 || orf19.2638 || || || Protein of unknown function; Spider biofilm induced || 1 -0.29 -0.23 -0.09 -0.38 1.30 -0.44 0.87 -0.35 0.68 0.42 -0.19 -0.69 1.35 1.71 -2.22 -0.50
5409 || orf19.4664 || NAT4 || || Putative histone acetyltransferase; involved in regulation of white-opaque switch; early-stage flow model biofilm induced; Spider biofilm induced || 1 -0.45 -0.30 0.05 -0.60 -0.53 0.03 0.18 0.21 -0.13 -0.49 1.00 0.34 2.17 1.14 -1.62 0.41
5410 || orf19.4664 || NAT4 || || Putative histone acetyltransferase; involved in regulation of white-opaque switch; early-stage flow model biofilm induced; Spider biofilm induced || 1 -0.27 0.09 0.15 -0.50 -0.14 0.47 0.54 0.88 0.36 -0.18 1.54 0.56 2.73 1.38 -1.72 0.73
5411 || orf19.5446 || || || Putative protein of unknown function; transcript is upregulated in clinical isolates from HIV+ patients with oral candidiasis; regulated by Ssn6 || 1 -0.14 0.53 0.86 0.27 -0.38 0.90 0.57 0.41 0.02 -0.28 0.26 -0.34 0.70 0.71 -1.84 0.37
5412 || orf19.4698 || PTC8 || || Predicted type 2C protein phosphatase, ser/thr-specific; required for hyphal growth; transcript induced by stress; flow model biofilm induced; Spider biofilm induced || 1 -0.55 -0.59 0.14 0.69 0.02 0.42 0.95 0.42 0.30 0.16 -0.38 -0.54 1.19 0.67 -0.22 0.13
5413 || orf19.5404 || || || Putative cell wall mannoprotein; repressed during the mating process; merged with orf19.5401 into orf19.5404.1; Spider biofilm induced || 1 -0.12 -0.21 0.21 0.03 0.13 0.18 0.14 0.19 0.29 -0.25 0.07 -0.43 0.38 0.13 -0.27 -0.11
5414 || orf19.7079 || || || Ortholog(s) have role in axial cellular bud site selection and cellular bud neck contractile ring localization || 1 0.12 0.03 -0.04 0.11 0.18 0.81 0.25 0.40 0.03 0.03 0.05 -0.50 0.59 0.21 -0.32 -0.22
5415 || orf19.7601 || || || Putative mitochondrial 2' O-ribose methyltransferase; predicted role in methylation of U(2791) in 21S rRNA; Spider biofilm induced || 1 0.27 0.13 0.89 0.95 0.24 0.63 0.84 0.81 -0.20 0.78 0.05 -1.29 0.70 1.58 -0.91 -0.29
5416 || orf19.1066 || GIG1 || || Protein induced by N-acetylglucosamine (GlcNAc); localized in cytoplasm; mutation causes increased resistance to nikkomycin Z || 1 0.31 0.43 1.17 0.57 0.59 0.61 0.45 0.71 0.80 -0.09 -0.63 -1.17 1.48 1.51 -0.73 -0.47
5417 || orf19.7316 || || || Putative phytanoyl-CoA dioxygenase family protein; mutation confers hypersensitivity to 5-fluorocytosine (5-FC), 5-fluorouracil (5-FU), and tubercidin (7-deazaadenosine); induced by nitric oxide || 1 0.00 -0.15 0.41 0.28 0.39 0.02 0.25 0.08 0.39 0.33 -0.70 -0.65 0.36 0.36 -0.30 -0.32
5418 || orf19.1942 || SGE1 || || Putative multidrug resistance factor; induced in low iron; regulated by Sef1, Sfu1, and Hap43 || 1 0.11 -0.17 0.08 0.28 0.02 0.04 -0.10 0.12 0.33 0.04 -0.52 -0.39 0.15 0.71 -0.05 -0.14
5419 || orf19.4743 || AFG1 || || Putative mitochondrial ATPase of the AAA family; similar but not orthologous to S. cerevisiae Afg1; mutant is viable; regulated by Sef1, Sfu1, and Hap43 || 1 -0.01 -0.14 0.22 -0.00 -0.09 -0.04 0.31 0.09 0.10 0.19 -0.82 -0.72 0.38 1.24 -0.07 0.01
5420 || orf19.2398 || || || Protein of unknown function; Hap43-repressed; transcript increased in azole-resistant strain overexpressing CDR1 and CDR2; possibly regulated by Tac1; induced by Mnl1 in weak acid stress; flow model biofilm induced; Spider biofilm induced || 1 0.19 0.30 0.41 0.60 -0.49 -1.11 0.62 -0.40 0.13 0.09 -0.76 -1.63 0.74 0.95 -0.77 -0.18
5421 || orf19.2945 || PUT4 || || Putative proline permease; fungal-specific (no human or murine homolog); repressed during the mating process || 1 0.23 0.36 0.62 0.38 -0.31 -0.43 0.08 -0.45 -0.34 -0.25 -0.10 -0.83 0.19 1.10 -0.74 -0.37
5422 || orf19.3277 || || || Ortholog of Candida albicans WO-1 : CAWG_01437 || 1 0.32 0.29 0.66 0.50 -0.31 -0.14 -0.28 -0.41 -0.13 0.17 -0.51 -0.39 0.61 0.93 -0.50 -0.00
5423 || orf19.2945 || PUT4 || || Putative proline permease; fungal-specific (no human or murine homolog); repressed during the mating process || 1 0.06 0.23 0.44 0.71 -0.46 -0.15 -0.18 -0.15 0.23 -0.11 -0.30 -0.40 0.11 0.89 -0.45 0.19
5424 || orf19.1932 || CFL4 || || C-terminus similar to ferric reductases; induced in low iron; Sfu1-repressed; ciclopirox olamine induced; colony morphology-related gene regulation by Ssn6; Hap43-repressed; Sef1-regulated || 1 0.18 0.03 0.97 1.25 -0.38 -0.06 -0.34 0.07 -0.11 -1.20 -1.41 -1.79 2.04 1.42 -0.62 0.53
5425 || orf19.1144 || || || Protein with SEL-1 like protein domain; early-stage flow model biofilm induced || 1 -0.06 -0.07 -0.08 -0.19 -0.26 -0.50 -0.23 -0.36 0.14 -0.50 0.06 -0.00 0.51 -0.01 0.00 0.22
5426 || orf19.2436 || || || Predicted protein serine/threonine kinase; Spider biofilm induced || 1 -0.07 -0.07 -0.28 -0.38 -0.10 -0.32 -0.13 -0.41 -0.28 0.20 -0.09 -0.16 0.41 0.14 0.04 0.04
5427 || orf19.2436 || || || Predicted protein serine/threonine kinase; Spider biofilm induced || 1 0.02 0.09 -0.22 -0.27 -0.21 -0.52 -0.29 -0.81 -0.48 -0.08 -0.25 -0.06 0.37 -0.04 -0.12 0.10
5428 || orf19.3521 || ARH2 || || Putative adrenodoxin-NADPH oxidoreductase; role in heme biosynthesis || 1 -0.14 -0.26 0.28 0.17 -1.03 -0.08 -0.75 -0.97 -0.23 -0.17 -0.90 -0.25 2.21 0.10 -0.74 0.72
5429 || orf19.3521 || ARH2 || || Putative adrenodoxin-NADPH oxidoreductase; role in heme biosynthesis || 1 -0.43 -0.52 -0.01 -0.02 -1.50 -0.38 -0.97 -1.16 -0.44 -0.37 -1.03 -0.40 2.19 0.05 -0.96 -0.13
5430 || orf19.2645 || || || Ortholog of Candida albicans WO-1 : CAWG_04710 || 1 -0.35 -0.48 -0.37 0.31 -0.97 -0.52 -0.15 -0.06 -0.14 0.35 -1.01 -0.18 0.75 1.25 -0.32 -0.42
5431 || orf19.2431 || || || Dubious open reading frame, only conserved in Candida dubliniensis; induced by alpha pheromone in SpiderM medium; mRNA binds She3; Spider biofilm induced; flow model biofilm repressed || 1 -0.29 -0.50 -0.54 -0.80 -0.78 -1.28 -0.50 -0.45 0.03 -0.23 -0.88 -0.23 2.29 0.49 0.71 0.08
5432 || orf19.2182 || BLM3 || || Putative proteasome activator; binds core proteasome and stimulates proteasome-mediated protein degradation by inducing gate opening; ortholog of S. cerevisiae Blm10; transcript regulated by Nrg1 and Mig1 || 1 -0.40 -0.41 -0.42 -0.68 -0.87 -0.91 0.32 0.06 0.23 -0.58 -0.67 -0.46 1.72 0.96 -0.01 -0.65
5433 || orf19.3794 || CSR1 || || Transcription factor; role in zinc homeostasis and regulation of Spider biofilm matrix; mutation affects filamentous growth; can suppress S. cerevisiae rok1 mutant inviability; Spider biofilm induced; mutants for abnormal Spider biofilms || 1 -0.17 -0.36 0.67 -0.07 -1.58 -1.15 -0.72 -0.93 -0.07 -0.98 -1.84 -1.42 2.31 2.01 0.20 -0.92
5434 || orf19.3794 || CSR1 || || Transcription factor; role in zinc homeostasis and regulation of Spider biofilm matrix; mutation affects filamentous growth; can suppress S. cerevisiae rok1 mutant inviability; Spider biofilm induced; mutants for abnormal Spider biofilms || 1 0.12 0.06 0.50 -0.26 -0.81 -1.19 -0.37 -0.58 -0.16 -0.77 -1.44 -1.27 2.39 2.26 0.34 -0.92
5435 || orf19.3794 || CSR1 || || Transcription factor; role in zinc homeostasis and regulation of Spider biofilm matrix; mutation affects filamentous growth; can suppress S. cerevisiae rok1 mutant inviability; Spider biofilm induced; mutants for abnormal Spider biofilms || 1 0.02 -0.01 0.31 -0.73 -1.15 -1.43 -0.36 -0.88 -0.37 -1.09 -1.61 -1.31 2.71 2.42 0.80 -1.17
5436 || orf19.3794 || CSR1 || || Transcription factor; role in zinc homeostasis and regulation of Spider biofilm matrix; mutation affects filamentous growth; can suppress S. cerevisiae rok1 mutant inviability; Spider biofilm induced; mutants for abnormal Spider biofilms || 1 0.17 0.22 0.57 -0.54 -0.62 -1.53 -0.23 -0.76 -0.35 -0.92 -1.16 -1.29 2.41 1.43 0.35 -0.99
5437 || orf19.5561 || STE23 || || Ortholog of S. cerevisiae Ste23 metalloprotease; role in N-terminal processing of pro-a-factor to the mature form; Tn mutation affects filamentous growth; Spider biofilm induced || 1 0.08 -0.07 -0.11 -0.20 -1.08 -1.22 -0.26 -0.79 -0.89 -0.69 -0.64 -0.39 1.97 1.29 0.04 0.28
5438 || orf19.5561 || STE23 || || Ortholog of S. cerevisiae Ste23 metalloprotease; role in N-terminal processing of pro-a-factor to the mature form; Tn mutation affects filamentous growth; Spider biofilm induced || 1 0.12 0.04 -0.08 -0.11 -0.84 -1.05 -0.32 -0.57 -0.76 -0.38 -0.45 -0.06 1.95 1.52 0.18 0.34
5439 || orf19.1534 || || || Ortholog of S. cerevisiae Zrt3, vacuolar membrane zinc transporter; predicted Kex2 substrate; induced in oralpharyngeal candidasis; flow model biofilm induced; Spider biofilm induced || 1 -0.55 0.38 -0.11 -0.50 -0.22 0.20 -0.31 -0.52 0.35 -0.77 -0.54 -0.39 1.91 1.24 0.15 -0.20
5440 || orf19.2431 || || || Dubious open reading frame, only conserved in Candida dubliniensis; induced by alpha pheromone in SpiderM medium; mRNA binds She3; Spider biofilm induced; flow model biofilm repressed || 1 -1.08 -0.73 -1.58 -1.22 -0.97 -2.15 -0.58 -0.97 -0.14 0.10 -0.18 0.78 2.14 0.92 0.43
5441 || orf19.2585 || || || Ortholog of Candida albicans WO-1 : CAWG_01548 || 1 -0.75 -0.49 -0.89 -1.24 0.26 -1.65 -0.41 -0.76 -0.15 0.25 1.25 2.98 1.21
5442 || orf19.4647 || HAP3 || || Predicted CCAAT-binding transcription factor that regulates respiration; Cap2-dependent induction in low iron; opaque specific, alkaline, ciclopirox olamine induced; regulated by Sef1, Sfu1, Hap43; Bcr1-regulated in RPMI a/a biofilms || 1 0.29 0.45 -0.95 -0.62 0.55 -0.37 -0.50 -0.49 -0.22 -0.46 -0.10 -0.66 0.96 1.78 -0.04 0.65
5443 || orf19.4647 || HAP3 || || Predicted CCAAT-binding transcription factor that regulates respiration; Cap2-dependent induction in low iron; opaque specific, alkaline, ciclopirox olamine induced; regulated by Sef1, Sfu1, Hap43; Bcr1-regulated in RPMI a/a biofilms || 1 -0.38 -0.55 -2.55 0.56 -0.87 -0.22 -0.48 -0.31 -0.30 -0.17 -1.48 1.76 2.62 0.09 1.17
5444 || orf19.4647 || HAP3 || || Predicted CCAAT-binding transcription factor that regulates respiration; Cap2-dependent induction in low iron; opaque specific, alkaline, ciclopirox olamine induced; regulated by Sef1, Sfu1, Hap43; Bcr1-regulated in RPMI a/a biofilms || 1 -0.97 -0.66 -2.40 -1.90 -0.54 -1.89 -0.06 -0.40 0.11 -0.15 -0.99 -1.59 2.07 2.00 -0.39 0.06
5445 || orf19.4784 || CRP1 || || Copper transporter; CPx P1-type ATPase; mediates Cu resistance; similar to Menkes and Wilson disease proteins; copper-induced; Tbf1-activated; suppresses Cu sensitivity of S. cerevisiae cup1 mutant; flow model biofilm induced || 1 -0.17 -0.02 -0.82 -0.28 -0.08 -1.33 -0.10 0.00 0.49 -0.79 0.43 -0.75 1.16 1.13 -0.18 0.72
5446 || orf19.7198 || || || CCR4-NOT complex component; involved in controlling mRNA initiation, elongation and degradation; rat catheter biofilm induced || 1 0.06 -0.20 -0.14 -0.33 -0.21 -0.20 -0.24 0.13 0.03 0.09 0.42 -0.40 0.60 0.55 -0.09 0.40
5447 || orf19.122 || CDC20 || || Activator of anaphase-promoting complex/cyclosome; induced under Cdc5 depletion; member of conserved Mcm1 regulon; mRNA expression peaks at cell-cycle G2/M phase; mRNA binds She3 and is localized to buds of yeast cells and to hyphal tips || 1 -0.27 -0.26 -0.19 -0.37 -1.26 -1.11 0.38 0.29 0.23 0.46 0.26 -0.15 0.26 0.31 -1.07 0.28
5448 || orf19.5879 || || || Has domain(s) with predicted oxidoreductase activity and role in metabolic process || 1 -0.82 -0.33 0.38 -0.66 -0.82 -0.73 0.35 -0.12 0.17 0.48 0.33 -0.31 0.52 0.32 -1.01 0.19
5449 || orf19.28 || || || Putative thiamine transmembrane transporter; Spider biofilm induced || 1 -0.35 -0.06 0.34 0.08 -0.77 -0.34 0.43 0.07 0.34 0.29 -0.54 -0.44 0.26 0.62 -1.07 -0.74
5450 || orf19.28 || || || Putative thiamine transmembrane transporter; Spider biofilm induced || 1 -0.64 -0.42 -0.52 -0.41 -0.82 -0.44 0.50 -0.06 0.08 0.16 -0.69 -0.05 0.13 0.64 -1.36 -0.69
5451 || orf19.691 || GPD2 || || Surface protein similar to glycerol 3-P dehydrogenase; binds host Factor H, FHL-1, plasminogen; regulated by Ssn6, Nrg1, Efg1; induced by cell wall regeneration, macrophage/pseudohyphal growth, core stress response; Spider biofilm induced || 1 -1.07 -0.96 -0.61 -0.39 -1.58 -0.67 0.55 -0.49 -0.04 -0.92 -0.17 -0.88 0.97 -0.13 -3.68 -0.25
5452 || orf19.691 || GPD2 || || Surface protein similar to glycerol 3-P dehydrogenase; binds host Factor H, FHL-1, plasminogen; regulated by Ssn6, Nrg1, Efg1; induced by cell wall regeneration, macrophage/pseudohyphal growth, core stress response; Spider biofilm induced || 1 -0.81 -0.97 -0.21 -0.20 -1.63 -0.52 0.85 -0.22 0.43 -0.46 -0.08 -0.87 0.97 0.05 -3.78 -0.33
5453 || orf19.2251 || AAH1 || || Adenine deaminase; purine salvage and nitrogen catabolism; colony morphology-related regulation by Ssn6; Hog1, CO2-induced; chlamydospore formation repressed in C. albicans and C. dubliniensis; rat catheter and F-12/CO2 biofilm induced || 1 0.25 0.13 -0.31 -1.34 -2.38 -0.95 1.28 -0.19 -0.33 -0.73 -1.13 -1.76 0.44 1.27 -3.82 -0.21
5454 || orf19.2251 || AAH1 || || Adenine deaminase; purine salvage and nitrogen catabolism; colony morphology-related regulation by Ssn6; Hog1, CO2-induced; chlamydospore formation repressed in C. albicans and C. dubliniensis; rat catheter and F-12/CO2 biofilm induced || 1 0.30 0.40 -0.12 -1.21 -2.05 -0.67 1.24 0.18 0.26 -0.32 -1.00 -1.48 0.77 1.45 -3.82 0.07
5455 || orf19.4286 || || || Protein of unknown function; flow model biofilm induced; Spider biofilm induced || 1 -0.08 -0.20 0.10 -0.03 -0.63 -0.63 0.38 -0.06 -0.02 -0.35 -0.11 -0.47 0.67 0.68 -0.98 0.68
5456 || orf19.2638 || || || Protein of unknown function; Spider biofilm induced || 1 -0.46 -0.28 -0.40 -0.63 -0.90 -1.61 0.64 -0.25 0.80 0.27 -0.58 -0.40 1.87 1.63 -1.47
5457 || orf19.6996 || MNN14 || || Predicted alpha-1,3-mannosyltransferase activity with a role in protein glycosylation; Hap43-repressed; Spider biofilm induced || 1 0.18 0.14 0.04 -0.54 -1.03 -0.37 0.89 0.51 0.51 0.19 -0.12 -0.46 1.08 1.06 -1.32 0.17
5458 || orf19.6996 || MNN14 || || Predicted alpha-1,3-mannosyltransferase activity with a role in protein glycosylation; Hap43-repressed; Spider biofilm induced || 1 0.20 0.25 0.01 -0.22 -0.81 -0.09 0.88 0.63 0.56 0.28 -0.09 -0.05 1.15 1.26 -1.13 0.37
5459 || orf19.4649 || ZCF27 || || Putative Zn(II)2Cys6 transcription factor || 1 0.21 0.27 -0.23 -0.51 -0.71 -0.31 0.46 0.00 0.49 0.22 -0.99 -0.09 1.78 0.77 -1.02 -0.54
5460 || orf19.4792 || || || Protein with a regulator of G-protein signaling domain; Plc1-regulated; Spider biofilm induced; rat catheter biofilm repressed || 1 0.21 0.12 0.12 0.17 -1.30 -0.29 1.50 -0.56 0.50 -0.22 -0.52 -0.90 1.16 0.64 -1.04 -0.28
5461 || orf19.104 || || || Protein of unknown function; induced by alpha pheromone in SpiderM medium || 1 -0.49 0.22 -1.98 0.21 -0.95 -0.96 0.42 0.09 0.88 0.19 -0.96 -1.41 0.52 1.26 -1.93 -0.45
5462 || orf19.5926 || ARG11 || || Putative ornithine transporter of the mitochondrial inner membrane; induced during the mating process || 1 -0.07 -0.19 -0.01 0.29 0.90 -1.19 -0.00 -0.99 -1.06 -0.15 -1.50 -0.97 1.12 0.29 -0.38 -1.32
5463 || orf19.3920 || || || Ortholog(s) have protein disulfide isomerase activity, protein disulfide oxidoreductase activity, role in protein folding and fungal-type vacuole localization || 1 -0.11 0.07 0.41 0.26 -0.13 -0.48 -0.33 -0.20 -0.18 0.23 -0.42 -0.14 0.11 0.01 -0.26 -0.67
5464 || orf19.7427 || || || Ortholog(s) have Golgi apparatus, fungal-type vacuole membrane localization || 1 -0.03 0.16 0.37 0.38 0.14 -0.28 -0.18 -0.23 0.04 0.26 -0.34 -0.20 0.46 -0.06 -0.22 -0.71
5465 || orf19.3555 || BUD14 || || Putative SH3-domain-containing protein; predicted role in bud-site selection; Spider biofilm induced || 1 -0.04 -0.03 0.28 0.11 0.00 -0.52 -0.07 -0.18 -0.01 -0.04 -0.49 -0.50 0.44 0.46 -0.06 -0.77
5466 || orf19.1794 || || || Ortholog(s) have RNA binding, translation regulator activity and role in Group I intron splicing, mitochondrial respiratory chain complex IV biogenesis, positive regulation of mitochondrial translation || 1 0.23 0.24 0.34 -0.10 -0.04 -0.40 0.01 -0.10 0.21 0.23 -0.36 -0.27 0.44 0.18 -0.06 -0.53
5467 || orf19.6138 || || || Protein similar to ferric reductase Fre10p; possibly an essential gene, disruptants not obtained by UAU1 method || 1 0.61 1.08 -0.38 -0.28 0.14 -0.41 0.11 -0.05 0.52 0.33 -0.49 -0.79 0.70 0.03 -0.74 -1.93
5468 || orf19.5933 || || || Protein of unknown function; transcript induced by benomyl treatment || 1 0.52 0.85 0.34 0.13 -0.54 0.06 0.50 0.40 0.98 0.87 -0.44 -1.11 0.98 -0.10 -0.72 -1.73
5469 || orf19.4651 || PGA53 || || GPI-anchored cell surface protein of unknown function; greater mRNA abundance observed in a cyr1 homozygous null mutant than in wild type || 1 0.60 0.45 -0.23 0.05 -0.07 -0.01 1.28 1.29 0.74 0.74 -1.26 -1.89 2.12 0.50 -0.40 -2.12
5470 || orf19.4651 || PGA53 || || GPI-anchored cell surface protein of unknown function; greater mRNA abundance observed in a cyr1 homozygous null mutant than in wild type || 1 0.05 -0.01 -0.87 -0.56 -0.23 -0.09 0.86 0.68 0.18 0.35 -1.20 -1.89 1.59 -0.01 -0.36 -1.88
5471 || orf19.5580 || TEL1 || || Ortholog(s) have protein serine/threonine kinase activity, telomeric DNA binding activity and role in DNA damage induced protein phosphorylation, double-strand break repair, histone phosphorylation, telomere maintenance || 1 0.02 -0.07 -0.19 -0.09 0.04 -0.14 0.20 0.17 0.38 0.17 -0.46 -0.36 0.24 -0.18 -0.19 -0.66
5472 || orf19.3134 || || || Protein of unknown function; flow model biofilm induced || 1 0.00 -0.02 -0.09 0.29 -1.45 0.16 1.10 0.04 1.04 0.70 -1.19 -1.01 0.47 0.51 -0.89 -3.31
5473 || orf19.792 || || || Ortholog(s) have protein serine/threonine kinase activity, role in activation of bipolar cell growth, protein phosphorylation, regulation of cytokinesis, regulation of mitotic sister chromatid segregation and cytosol, nucleus localization || 1 0.79 0.34 0.82 1.01 -0.03 -0.01 0.91 0.34 -0.05 0.61 -1.34 -0.80 0.67 0.30 -0.12 -1.66
5474 || orf19.4571 || || || CoA-transferase family protein; rat catheter biofilm repressed || 1 0.45 0.31 0.85 -0.29 -0.43 -0.38 0.55 -0.30 0.30 0.77 -1.02 -1.17 0.11 -0.03 -0.23 -0.96
5475 || orf19.5933 || || || Protein of unknown function; transcript induced by benomyl treatment || 1 0.23 0.04 0.28 -0.47 0.05 -0.96 1.18 0.34 0.11 0.54 -1.44 -2.42 0.27 0.64 -1.06 -0.83
5476 || orf19.940 || BUD2 || || GTPase activating protein (GAP) for Rsr1; negative regulator of filament branching, acts in hyphal growth guidance; required for wild-type budding pattern; induced in low iron; regulated by tyrosol and cell density || 1 0.35 0.13 -0.18 -0.04 -0.08 -0.43 0.10 0.15 -0.38 -0.10 -0.48 -0.44 0.47 0.35 -0.21 -0.17
5477 || orf19.3277 || || || Ortholog of Candida albicans WO-1 : CAWG_01437 || 1 0.07 0.29 -0.85 -0.52 -1.30 -0.56 -0.01 0.29 -1.20 -0.26 -1.45 -0.80 0.70 0.95 -1.30 -0.93
5478 || orf19.3663 || PHO91 || || Putative low-affinity phosphate transporter; fungal-specific (no human or murine homolog) || 1 0.28 -0.22 -0.00 -0.16 -0.44 -0.26 0.15 0.02 0.15 -0.19 -0.57 -0.50 0.43 0.67 -0.51 -0.59
5479 || orf19.3190 || HAL9 || || Putative Zn(II)2Cys6 transcription factor; gene in zinc cluster region of Chr. 5; induced by Mnl1 in weak acid; similar to S. cerevisiae Hal9, a putative transcription factor involved in salt tolerance || 1 -0.24 -0.11 -0.21 -0.31 0.23 -0.14 0.12 0.16 0.29 -0.08 -0.56 -0.77 -0.01 0.56 -0.25 -1.15
5480 || orf19.3190 || HAL9 || || Putative Zn(II)2Cys6 transcription factor; gene in zinc cluster region of Chr. 5; induced by Mnl1 in weak acid; similar to S. cerevisiae Hal9, a putative transcription factor involved in salt tolerance || 1 0.03 -0.01 -0.22 -0.31 0.22 -0.25 0.25 0.24 0.24 0.03 -0.57 -0.83 0.20 0.42 -0.22 -0.80
5481 || orf19.3756 || CHR1 || || Predicted DEAD-box ATP-dependent RNA helicase; functional homolog of S. cerevisiae Rok1; Hap43-induced; Spider biofilm induced || 1 0.37 0.21 0.18 -0.38 0.02 -0.31 0.29 -0.34 -1.15 -0.61 -1.00 -2.18 1.43 1.83 -0.62 -2.92
5482 || orf19.3756 || CHR1 || || Predicted DEAD-box ATP-dependent RNA helicase; functional homolog of S. cerevisiae Rok1; Hap43-induced; Spider biofilm induced || 1 0.49 0.47 -0.59 -1.02 0.03 -0.43 0.59 -0.26 -1.62 -0.41 -1.74 -2.71 2.03 2.25 -1.04 -3.93
5483 || orf19.3756 || CHR1 || || Predicted DEAD-box ATP-dependent RNA helicase; functional homolog of S. cerevisiae Rok1; Hap43-induced; Spider biofilm induced || 1 0.45 0.59 -0.61 -1.30 0.51 -0.36 0.74 -0.19 -1.70 -0.45 -1.57 -2.68 2.14 2.38 -0.80 -3.76
5484 || orf19.3756 || CHR1 || || Predicted DEAD-box ATP-dependent RNA helicase; functional homolog of S. cerevisiae Rok1; Hap43-induced; Spider biofilm induced || 1 0.58 0.22 -0.19 -0.93 0.26 -0.49 0.56 0.16 -1.46 -0.55 -0.99 -2.28 1.69 2.08 -0.27 -2.12
5485 || orf19.5241 || SNT1 || || Ortholog of S. cerevisiae Snt1; an NAD-independent histone deacetylase; heterozygous transposon mutation affects filamentous growth; null mutants are viable || 1 0.42 0.44 0.06 -0.43 0.24 0.08 0.22 -0.16 -0.05 -0.33 -0.75 -0.66 0.87 0.35 -0.10 -0.68
5486 || orf19.1066 || GIG1 || || Protein induced by N-acetylglucosamine (GlcNAc); localized in cytoplasm; mutation causes increased resistance to nikkomycin Z || 1 -0.09 0.05 0.10 -0.38 0.95 0.49 0.24 0.45 -0.34 -0.45 -0.94 -1.77 1.50 1.58 -1.47 -0.72
5487 || orf19.4698 || PTC8 || || Predicted type 2C protein phosphatase, ser/thr-specific; required for hyphal growth; transcript induced by stress; flow model biofilm induced; Spider biofilm induced || 1 -0.95 -0.59 -0.42 0.33 -0.41 -0.19 0.89 0.06 -0.32 0.09 -0.47 -1.18 1.65 0.57 -0.51 -1.12
5488 || orf19.5342.1 || MTR2 || || Nuclear export protein; member of NTF2 family; monomeric in solution; interacts with Mex67p via the NTF2-like domain || 1 -0.09 -0.20 -0.24 -0.27 -0.08 0.01 0.30 0.14 -0.04 0.16 -0.03 -0.12 0.45 0.15 -0.17 -0.23
5489 || orf19.3479 || || || Predicted ORF in Assemblies 19, 20 and 21; merged with orf19.3477 || 1 0.61 0.88 -0.44 -0.25 -0.11 -0.64 1.18 1.07 -0.33 0.94 -0.09 -1.81 1.13 0.84 -0.22 -0.42
5490 || orf19.1352 || TIM22 || || Mitochondrial inner membrane protein; predicted role in protein import; Hap43-repressed gene; flow model biofilm induced; Spider biofilm repressed || 1 0.53 0.09 -0.50 -0.65 -0.41 -0.64 0.26 0.54 0.55 0.50 -0.21 -0.86 0.35 0.69 -0.40 -0.25
5491 || orf19.3219 || || || Ortholog of S. cerevisiae Sia1; involved in activation of the Pma1 plasma membrane H+-ATPase by glucose in S. cerevisiae; Spider biofilm induced || 1 -0.07 -0.04 -0.50 -0.05 -0.89 -1.40 0.36 0.28 -0.19 -0.06 -0.39 -0.76 0.95 0.68 0.05 -0.39
5492 || orf19.7303 || || || Ortholog of C. dubliniensis CD36 : Cd36_34495, Candida tropicalis MYA-3404 : CTRG_05947 and Candida albicans WO-1 : CAWG_02181 || 1 -0.16 -0.12 -0.04 -0.38 -0.17 -2.54 0.42 0.19 0.22 0.01 -0.51 -1.29 1.79 1.06 -0.35
5493 || orf19.2506 || || || Protein of unknown function; opaque-specific transcript; induced during chlamydospore formation in both C. albicans and C. dubliniensis; Hog1-repressed; Spider biofilm induced || 1 0.16 -0.01 -0.95 -0.33 -0.73 -1.70 1.10 0.75 1.45 0.85 -0.56 -1.55 2.46 0.95 -0.49 -0.45
5494 || orf19.2506 || || || Protein of unknown function; opaque-specific transcript; induced during chlamydospore formation in both C. albicans and C. dubliniensis; Hog1-repressed; Spider biofilm induced || 1 0.33 0.28 -1.16 -0.88 -0.32 -1.15 1.45 0.87 1.38 1.17 -0.51 -1.50 2.49 0.80 -0.14 -0.99
5495 || orf19.2506 || || || Protein of unknown function; opaque-specific transcript; induced during chlamydospore formation in both C. albicans and C. dubliniensis; Hog1-repressed; Spider biofilm induced || 1 0.46 0.39 -1.58 -0.78 -0.46 -1.60 1.43 0.58 1.20 0.94 -0.71 -1.69 2.73 1.00 -0.11 -1.26
5496 || orf19.2506 || || || Protein of unknown function; opaque-specific transcript; induced during chlamydospore formation in both C. albicans and C. dubliniensis; Hog1-repressed; Spider biofilm induced || 1 0.56 0.59 -1.29 -0.72 -0.48 -1.27 1.41 0.55 1.16 0.79 -0.83 -2.00 2.62 1.02 -0.35 -1.27
5497 || orf19.5902 || RAS2 || || Protein similar to S. cerevisiae Ras2; has opposite effects to Ras1; Tn mutation affects filamentous growth; rat catheter and Spider biofilm induced || 1 0.08 0.09 -0.81 -0.76 -0.11 -1.23 1.63 0.54 0.91 0.00 -0.12 -1.62 1.45 1.64 0.28 -0.55
5498 || orf19.5902 || RAS2 || || Protein similar to S. cerevisiae Ras2; has opposite effects to Ras1; Tn mutation affects filamentous growth; rat catheter and Spider biofilm induced || 1 -0.37 -0.50 -1.01 -1.45 -1.74 -2.62 1.99 0.60 0.86 -0.06 -0.70 -1.55 1.48 2.06 -0.05 -0.49
5499 || orf19.4927 || BNI1 || || Formin; role in cytoskeletal organization, cell polarity; role in systemic virulence in mouse; cell-cycle regulated localization to site of polarized growth, bud neck; localizes to Spitzenkorper of hyphae, minor localization at septum || 1 -0.03 0.13 -0.49 -0.74 -0.77 -1.30 0.97 0.69 0.64 0.20 -0.10 -0.43 0.88 0.57 -0.02 -0.30
5500 || orf19.4645 || BEM1 || || Protein required for wild-type budding, hyphal growth, and virulence in a mouse systemic infection; suppresses pseudohyphal and filamentous growth defects of various S. cerevisiae mutants and heat sensitivity of S. cerevisiae cdc24-4 mutant || 1 0.23 0.37 -0.66 -1.12 -0.17 -1.96 0.64 1.03 0.55 0.22 0.10 -1.40 1.41 0.19 -0.38 -0.93
5501 || orf19.5087 || BUD6 || || Protein required for Spitzenkorper formation in hyphal cells (wild-type localization of Mlc1p to the Spitzenkorper); localizes to polarisome || 1 0.07 0.07 -0.30 -0.39 -0.07 -0.70 0.24 0.16 0.27 -0.30 0.30 -0.41 0.49 -0.12 -0.07 -0.35
5502 || orf19.6779 || PRO2 || || Putative gamma-glutamyl phosphate reductase with a predicted role in proline biosynthesis; regulated by Gcn2p and Gcn4p || 1 0.14 0.49 -0.37 -0.47 0.36 -0.89 0.59 0.34 0.82 -0.01 -0.10 -0.09 0.64 0.18 -0.22 0.03
5503 || orf19.7303 || || || Ortholog of C. dubliniensis CD36 : Cd36_34495, Candida tropicalis MYA-3404 : CTRG_05947 and Candida albicans WO-1 : CAWG_02181 || 1 0.17 -0.50 -0.74 0.28 -3.71 0.83 0.57 3.44 0.44 -1.75 -0.40 1.15 1.25 0.17
5504 || orf19.7545 || || || Protein similarity to mutator-like element (MULE) transposase || 1 0.32 0.46 0.05 -0.01 -0.65 -0.61 -0.09 0.65 -0.05 0.25 -0.85 -0.67 0.17 0.34 -0.21 -0.10
5505 || orf19.782 || || || Ortholog(s) have serine hydrolase activity, triglyceride lipase activity, role in lipid homeostasis and lipid particle localization || 1 0.01 0.02 -0.34 0.12 -0.56 -0.73 0.27 0.16 -0.06 -0.31 -0.77 -0.18 0.08 0.37 0.11 -0.22
5506 || orf19.6512 || EXO70 || || Predicted subunit of the exocyst complex, involved in exocytosis; localizes to a crescent on the surface of the hyphal tip || 1 0.14 0.29 -0.11 0.10 -0.16 -0.40 0.10 0.01 -0.04 -0.20 -0.39 -0.34 0.26 0.26 0.31 -0.07
5507 || orf19.2841 || PGM2 || || Ortholog of S. cerevisiae Pgm2; induced in planktonic culture; Tye7p-regulated; flow model biofilm induced; rat catheter biofilm repressed || 1 -0.13 -0.05 0.22 -0.40 -0.92 -0.17 0.30 -0.45 0.40 -1.03 -1.11 -0.44 0.80 0.75 -0.36 -0.10
5508 || orf19.3278 || GSY1 || || UDP glucose/starch glucosyltransferase; transcript repressed by yeast-hyphal switch, Efg1-regulated; strong oxidative stress induced; colony morphology-related regulation by Ssn6; stationary phase enriched; flow model biofilm induced || 1 0.28 0.32 0.16 -0.64 -0.96 -0.69 0.29 -0.04 0.62 -0.41 -0.95 -0.48 0.49 0.31 -0.13 -0.27
5509 || orf19.3278 || GSY1 || || UDP glucose/starch glucosyltransferase; transcript repressed by yeast-hyphal switch, Efg1-regulated; strong oxidative stress induced; colony morphology-related regulation by Ssn6; stationary phase enriched; flow model biofilm induced || 1 0.16 0.14 0.24 -0.63 -1.06 -0.77 0.03 -0.31 0.81 -0.30 -1.26 -0.83 0.37 0.09 -0.36 -0.40
5510 || orf19.3278 || GSY1 || || UDP glucose/starch glucosyltransferase; transcript repressed by yeast-hyphal switch, Efg1-regulated; strong oxidative stress induced; colony morphology-related regulation by Ssn6; stationary phase enriched; flow model biofilm induced || 1 -0.12 0.15 0.08 -0.80 -1.36 -1.02 -0.00 -0.40 0.61 -0.55 -1.45 -1.12 0.25 -0.23 -0.55 -0.76
5511 || orf19.3278 || GSY1 || || UDP glucose/starch glucosyltransferase; transcript repressed by yeast-hyphal switch, Efg1-regulated; strong oxidative stress induced; colony morphology-related regulation by Ssn6; stationary phase enriched; flow model biofilm induced || 1 -0.05 0.01 -0.29 -1.02 -1.45 -0.89 0.05 -0.43 0.58 -0.60 -1.37 -0.66 0.24 0.21 -0.37 -0.44
5512 || orf19.3278 || GSY1 || || UDP glucose/starch glucosyltransferase; transcript repressed by yeast-hyphal switch, Efg1-regulated; strong oxidative stress induced; colony morphology-related regulation by Ssn6; stationary phase enriched; flow model biofilm induced || 1 -0.14 -0.10 -0.15 -1.04 -1.46 -0.97 -0.03 -0.59 0.46 -0.32 -1.62 -0.81 0.08 0.30 -0.65 -0.18
5513 || orf19.2792 || IST2 || || Ortholog(s) have lipid binding activity, role in endoplasmic reticulum membrane organization, regulation of phosphatidylinositol dephosphorylation and cellular bud membrane, cortical endoplasmic reticulum localization || 1 -0.01 0.02 -0.08 -1.29 -0.24 -0.07 0.24 -0.62 0.49 -0.33 -1.69 -1.03 0.14 0.13 -0.05 -0.75
5514 || orf19.2792 || IST2 || || Ortholog(s) have lipid binding activity, role in endoplasmic reticulum membrane organization, regulation of phosphatidylinositol dephosphorylation and cellular bud membrane, cortical endoplasmic reticulum localization || 1 0.36 0.38 0.19 -1.05 0.14 0.28 0.55 -0.06 0.55 -0.03 -1.16 -0.51 0.55 0.12 -0.16 -0.31
5515 || orf19.928 || || || Ortholog of C. dubliniensis CD36 : Cd36_50610, C. parapsilosis CDC317 : CPAR2_303690, Candida tenuis NRRL Y-1498 : CANTEDRAFT_93989 and Debaryomyces hansenii CBS767 : DEHA2E15400g || 1 0.32 0.39 -0.07 -0.20 -0.23 -0.09 0.26 -0.54 -0.12 -0.26 -0.62 -0.33 1.27 -0.29 -0.16 -0.50
5516 || orf19.184 || MDM10 || || Predicted component of the mitochondrial sorting and assembly machinery (SAM complex) and ER-mitochondria encounter structure (ERMES) complex with a role in protein import into mitochondria || 1 0.01 0.18 0.10 0.04 -0.05 -0.05 0.10 -0.19 0.17 -0.20 -0.04 0.20 0.34 0.01 -0.22 -0.23
5517 || orf19.2018 || || || Protein with a predicted DnaJ chaperone domain and a CSL-type zinc finger; Spider biofilm induced || 1 -0.17 -0.10 -0.02 -0.47 -0.32 -0.16 0.01 -0.29 -0.08 0.66 -0.47 -0.02 0.63 0.23 -0.06 -1.24
5518 || orf19.4017 || || || Ortholog of C. dubliniensis CD36 : Cd36_54840, C. parapsilosis CDC317 : CPAR2_100270, Candida tenuis NRRL Y-1498 : cten_CGOB_00242 and Debaryomyces hansenii CBS767 : DEHA2D14058g || 1 -0.59 -0.16 0.73 -1.03 -0.41 -0.40 -0.04 -0.59 -0.54 -0.46 -0.03 0.83 -0.23
5519 || orf19.3089 || || || Predicted mitochondrial intermembrane space protein; predicted role in phospholipid metabolism; rat catheter and Spider biofilm induced || 1 -0.40 -0.72 -0.06 0.14 0.17 0.31 0.33 0.80 -0.70 -0.21 -0.36 -0.17 1.06 0.94 0.20 -0.79
5520 || orf19.2638 || || || Protein of unknown function; Spider biofilm induced || 1 -0.13 0.29 1.29 0.67 0.05 0.29 0.86 -0.57 0.11 -0.58 0.00 0.68 0.98 -0.64 -1.46
5521 || orf19.5053 || || || Ortholog(s) have acetyltransferase activity, chromatin binding activity || 1 0.12 0.04 0.32 0.44 0.03 -0.57 -0.01 0.31 -0.12 0.12 -0.32 -0.13 0.14 0.48 0.00 -0.29
5522 || orf19.344 || || || Protein of unknown function; upregulated by fluphenazine treatment or in an azole-resistant strain that overexpresses CDR1 and CDR2; transcript possibly regulated by Tac1 || 1 -0.43 -0.71 0.33 0.85 0.08 -0.16 0.27 0.72 -0.47 0.24 -0.49 0.15 0.06 0.41 -0.15 0.00
5523 || orf19.290 || KRE5 || || UDP-glucose:glycoprotein glucosyltransferase; 1,6-beta-D-glucan biosynthesis, hyphal growth, virulence in mouse IV model; partially complements S. cerevisiae kre5 mutant defects; flow biofilm repressed, Bcr1-repressed in RPMI a/a biofilms || 1 0.15 0.18 0.16 -0.02 -0.01 -0.23 0.12 0.20 -0.28 0.48 -0.11 -0.22 -0.65 0.34 -0.24 0.33
5524 || orf19.1192 || DNA2 || || Protein similar to S. cerevisiae Dna2p, which is a DNA replication factor involved in DNA repair; induced under hydroxyurea treatment || 1 0.06 0.07 -0.25 0.13 0.29 -0.04 -0.18 0.20 -0.35 0.66 -0.04 -0.44 -0.62 0.21 -0.22 -0.17
5525 || orf19.1192 || DNA2 || || Protein similar to S. cerevisiae Dna2p, which is a DNA replication factor involved in DNA repair; induced under hydroxyurea treatment || 1 -0.36 -0.20 0.04 0.09 0.20 -0.60 -0.26 0.16 -0.28 0.95 0.23 -0.77 -1.07 0.41 -0.28 -0.21
5526 || orf19.5179 || LIP5 || || Cold-activated secreted lipase, differentially expressed lipase gene family member with possible roles in nutrition and acidic microenvironment; LIP5 and LIP8 expressed at all stages of mucosal and systemic infection; affects filamentation || 1 -0.73 -0.81 -0.23 -0.53 0.35 -0.89 0.31 -0.50 -0.05 0.95 -0.28 -1.07 -0.29 0.64 -0.59 -0.21
5527 || orf19.134 || || || Protein of unknown function; overlaps retrotransposon Tca13; ciclopirox olamine induced || 1 -0.39 -0.37 0.22 0.95 -0.63 0.10 -0.38 1.03 0.26 -2.97 -1.39 0.89 0.35
5528 || orf19.257 || || || Transcription is negatively regulated by Sfu1p; repressed by nitric oxide || 1 -0.87 -0.37 0.08 -0.37 -0.15 -0.60 0.57 -0.26 0.59 -0.62 -2.23 -0.02 -0.70 1.51
5529 || orf19.2395 || IME2 || || Putative serine/threonine protein kinase; mutation confers hypersensitivity to amphotericin B || 1 -0.32 -0.90 0.36 -0.18 0.01 -0.08 -0.39 0.08 -0.46 0.51 -0.81 -0.65 -0.62 -0.04 -0.23 0.64
5530 || orf19.1741 || DIT1 || || Ortholog(s) have catalytic activity and role in ascospore wall assembly || 1 -0.14 -1.15 0.75 -0.23 0.09 0.19 -0.23 0.53 -0.03 0.36 -0.17 -0.31 0.08 0.03 -0.11 0.59
5531 || orf19.5389 || FKH2 || || Forkhead transcription factor; morphogenesis regulator; required for wild-type hyphal transcription, cell separation, and for virulence in cell culture; mutant lacks true hyphae, is constitutively pseudohyphal; upregulated in RHE model || 1 -0.48 -0.65 0.63 0.36 -0.06 -0.01 -0.30 -0.40 -0.03 -0.28 0.49 -0.42 0.30 -0.25 -0.10 0.17
5532 || orf19.937 || || || Ortholog of Candida albicans WO-1 : CAWG_04446 || 1 -0.17 -0.70 0.17 0.13 -0.26 -0.07 0.33 0.21 -0.34 0.04 -0.90 0.22 0.40 -0.37
5533 || orf19.7299.1 || || || Ortholog of Candida albicans WO-1 : CAWG_02179 || 1 0.14 -0.97 -0.01 -0.23 0.01 -0.53 0.40 -0.12 -0.98 0.61 -0.04 0.56 -0.53
5534 || orf19.3671 || || || Dubious open reading frame || 1 -0.82 -0.60 0.55 -0.21 0.67 -0.01 0.14 -0.73 -0.03 -0.07 0.02 -0.91 0.56 0.13 0.03 -0.88
5535 || orf19.4949 || || || Ortholog of C. parapsilosis CDC317 : CPAR2_801735, C. dubliniensis CD36 : Cd36_84090, Candida orthopsilosis Co 90-125 : CORT_0B03960 and Spathaspora passalidarum NRRL Y-27907 : SPAPADRAFT_141253 || 1 -0.39 -0.29 0.60 -0.52 0.01 0.23 -0.05 -0.06 0.31 0.08 0.00 -0.14 0.10 0.48 -0.46 -0.19
5536 || orf19.4217 || || || Ortholog of Candida tropicalis MYA-3404 : CTRG_03197, Candida lusitaniae ATCC 42720 : CLUG_02837 and Candida albicans WO-1 : CAWG_04597 || 1 -0.48 -0.57 1.02 -1.36 0.12 0.23 0.12 -0.76 0.72 -0.20 -0.54 -1.58 0.22 -1.18 -0.24
5537 || orf19.5308 || || || Protein of unknown function; induced by Rgt1 || 1 -0.01 -0.33 0.62 -0.59 0.14 -0.95 -0.37 0.00 -0.37 0.31 -2.00 0.80 -0.29 -0.23
5538 || orf19.6575 || || || Protein of unknown function; rat catheter biofilm repressed || 1 -0.29 -0.27 0.52 -0.29 0.05 0.25 -0.30 0.07 0.31 -2.54 0.43 -0.41 0.27
5539 || orf19.1207 || || || Ortholog of C. dubliniensis CD36 : Cd36_33200 and Candida albicans WO-1 : CAWG_03416 || 1 -0.55 0.01 0.89 -0.01 -0.18 0.89 -0.28 -0.22 -0.28 0.30 -0.57 -2.37 0.13 0.62 0.09 0.12
5540 || orf19.584 || || || Has domain(s) with predicted heme binding, peroxidase activity and role in oxidation-reduction process, response to oxidative stress || 1 -0.67 -0.33 0.24 0.77 0.28 0.33 -0.14 0.03 0.24 -0.49 -0.11 0.09
5541 || orf19.2957 || || || Protein required for transfer of mannosylphosphate; induced by alpha pheromone in SpiderM medium || 1 -0.53 -0.63 0.05 0.52 -0.12 0.66 -0.41 -0.08 0.55 0.03 -0.41 -0.74 -0.33 0.51 -0.05 -0.09
5542 || orf19.609 || || || Protein of unknown function; white cell specific transcript || 1 -0.14 -0.23 0.13 0.52 0.04 0.64 -0.90 -0.53 1.33 0.83 -0.48 -0.85 -0.46 1.45 0.10 0.62
5543 || orf19.7395 || || || Ortholog of Candida albicans WO-1 : CAWG_02922 || 1 -0.24 0.53 0.39 0.80 -1.17 -0.55 1.03 0.20 -0.84 0.39 0.45 1.05
5544 || orf19.3169 || || || Ortholog(s) have role in RNA polymerase II complex localization to nucleus, RNA polymerase III complex localization to nucleus, establishment of mitotic sister chromatid cohesion and cytosol, nucleus localization || 1 0.36 0.03 0.44 0.30 0.33 1.02 -0.36 -0.25 0.36 -0.08 0.22 -0.58 -0.09 0.32 -0.16 0.09
5545 || orf19.3284 || || || Ortholog of Candida albicans WO-1 : CAWG_01431 || 1 0.05 0.86 0.92 0.12 1.16 -0.24 0.22 0.43 0.19 0.09 -1.38 -0.06 1.57 -0.59
5546 || orf19.6267 || || || Ortholog of C. dubliniensis CD36 : Cd36_06020, C. parapsilosis CDC317 : CPAR2_803380, Candida tenuis NRRL Y-1498 : CANTEDRAFT_91858 and Pichia stipitis Pignal : PICST_30337 || 1 -0.26 0.35 1.12 -0.13 1.60 -1.00 0.34 -0.93 0.12 -1.16 -1.01 -0.19 0.71
5547 || orf19.5649 || || || Ortholog of Candida lusitaniae ATCC 42720 : CLUG_00275 and Candida albicans WO-1 : CAWG_03759 || 1 -0.16 -0.40 0.98 -0.45 0.74 0.03 -0.71 -0.54 0.22 0.12 0.31 -0.44 -0.14 1.17 0.56 -0.33
5548 || orf19.1581 || || || Planktonic growth-induced gene || 1 -0.98 -0.45 0.51 0.07 -0.34 0.33 -0.06 0.58 0.09 -0.48 -0.23 -0.75 -0.43 -0.04 0.47 0.09
5549 || orf19.7600 || FDH3 || || Glutathione-dependent formaldehyde dehydrogenase; glycine catabolism; repressed by Efg1 in yeast, not hyphal growth conditions; induced by Mnl1 under weak acid stress; Spider biofilm repressed || 1 -0.28 -0.38 0.17 0.00 -0.52 0.22 0.45 0.46 -0.65 0.01 -1.32 0.54 -0.47 0.26
5550 || orf19.1010 || MNT3 || || Mannosyltransferase; transcription elevated in cyr1, chk1, nik1, and sln1 homozygous null mutants; fungal-specific (no human or murine homolog) || 1 -0.29 -0.29 -0.14 -0.55 -0.32 0.25 0.08 0.09 -0.46 -0.49 0.23 0.36 -0.38 0.24 -0.17 0.23
5551 || orf19.1551 || || || Predicted protein of unknown function; overlaps CPR3/orf19.1552 || 1 -0.26 -0.28 0.33 -0.21 -0.36 -0.03 0.13 -0.70 -0.54 -0.11 0.42 -0.37 -0.62 0.42
5552 || orf19.5526 || SEC20 || || Essential protein; similar to S. cerevisiae Sec20p; depletion causes membrane accumulation and drug sensitivity; expression regulated by growth phase; O-mannosylation regulates proteolysis; does not complement S. cerevisiae sec20-1 mutant || 1 -0.03 -0.24 0.15 -0.15 -0.13 0.02 -0.02 0.00 -0.16 -0.46 0.13 0.09 -0.19 -0.03 -0.29 0.21
5553 || orf19.2032 || || || Protein of unknown function; rat catheter biofilm induced || 1 -0.62 -0.43 0.86 -0.09 0.00 0.18 -0.45 -0.38 0.07 0.07 0.47 -0.69 -0.07 0.41 -0.82 -0.14
5554 || orf19.6222 || SPO22 || || Ortholog(s) have role in regulation of synaptonemal complex assembly and condensed nuclear chromosome localization || 1 -0.30 -0.10 0.50 -0.12 -0.50 0.14 -0.18 -0.48 -0.15 -0.01 0.82 -0.20 -0.35 -0.89 -0.39
5555 || orf19.2736 || HFL2 || || HAP5-like; ortholog of S. cerevisiae Bur6, a heterodimeric NC2 transcription regulator complex subunit; flucytosine induced || 1 -0.14 -0.57 0.36 0.13 -0.98 0.22 -0.42 -0.29 -0.24 0.24 0.24 -0.43 -0.20 0.25 -0.86 -0.31
5556 || orf19.7091 || || || Protein of unknown function; induced by nitric oxide; Spider biofilm repressed || 1 0.46 0.35 0.79 1.39 -1.05 0.16 -0.31 0.27 -0.58 0.08 0.30 -0.63 -1.54 0.64 -1.34 0.16
5557 || orf19.7091 || || || Protein of unknown function; induced by nitric oxide; Spider biofilm repressed || 1 -0.01 -0.10 0.02 0.48 -1.20 0.42 -0.26 0.19 -1.34 -0.10 0.64 -0.64 -2.17 0.62 -1.69 0.22
5558 || orf19.3406 || || || Predicted chloride transporter; member of conserved Mcm1 regulon; Spider biofilm repressed || 1 -0.09 0.04 0.70 0.57 0.20 1.15 -0.59 -0.06 -1.69 -0.46 0.90 -0.90 -1.02 0.37 -0.72 0.92
5559 || orf19.3406 || || || Predicted chloride transporter; member of conserved Mcm1 regulon; Spider biofilm repressed || 1 0.54 0.45 0.84 0.71 0.16 0.93 -0.13 0.31 -0.88 -0.21 0.88 -0.80 -0.39 0.33 -0.50 0.61
5560 || orf19.2035 || || || Ortholog of C. parapsilosis CDC317 : CPAR2_212930, C. dubliniensis CD36 : Cd36_15830, Candida orthopsilosis Co 90-125 : CORT_0A12240 and Candida tropicalis MYA-3404 : CTRG_01155 || 1 -0.38 -0.13 -0.54 1.03 -0.02 -0.37 -0.37 -0.00 0.21 0.03 0.29 -0.25 0.57 0.22 0.09 0.62
5561 || orf19.6119 || || || Protein of unknown function; Spider biofilm repressed || 1 0.07 0.28 0.35 0.35 -0.18 -0.27 -0.35 0.07 0.01 -0.47 0.03 0.08 0.08 0.02 -0.09 0.17
5562 || orf19.5399 || IFF11 || || Secreted protein required for normal cell wall structure and for virulence; member of the IFF family; Hap43p-repressed gene || 1 0.20 0.26 0.42 0.68 -0.13 -0.36 0.09 0.36 -0.18 -1.02 0.08 -0.04 0.10 -0.44 -0.03 0.33
5563 || orf19.5306 || || || Ortholog of C. dubliniensis CD36 : Cd36_43820 and Candida albicans WO-1 : CAWG_03393 || 1 -0.20 0.39 0.25 0.76 0.16 -0.33 0.12 0.56 -0.90 -0.33 -0.21 0.21 -0.14 -0.63 -0.06 0.25
5564 || orf19.2282 || || || Has domain(s) with predicted catechol 1,2-dioxygenase activity, ferric iron binding activity and role in catechol-containing compound metabolic process, oxidation-reduction process || 1 0.12 0.21 0.12 0.57 0.16 -0.22 -0.22 0.37 -0.33 -0.35 -0.12 -0.26 0.08 -0.38 0.23 0.51
5565 || orf19.598 || || || Ortholog of Candida albicans WO-1 : CAWG_02092 || 1 -0.21 0.37 -0.01 1.01 0.24 0.17 0.43 -0.77 -0.22 0.08 -0.59 -0.13 0.10 1.26
5566 || orf19.6547 || || || Ortholog of Candida albicans WO-1 : CAWG_05528 || 1 -0.01 -0.07 0.31 0.57 0.03 -0.11 0.20 0.20 0.26 -0.11 -0.16 -0.37 -0.25 0.12 0.35 -0.04
5567 || orf19.217 || || || Ortholog(s) have sequence-specific DNA binding activity || 1 -0.19 -0.02 0.14 0.92 -0.26 -1.07 -0.55 0.29 0.14 0.26 0.20 -0.72 -0.06 -0.23 0.27 0.30
5568 || orf19.1353 || || || Protein of unknown function; repressed by yeast-hypha switch; Ras1-regulated; oral infection induced; mutants defective in damage to oral epithelium; flow model biofilm induced; Spider biofilm induced || 1 -0.77 0.02 0.05 -1.08 -1.26 -0.25 -0.10 -1.22 0.05 -0.15 -1.26 -0.48 0.43 0.23 -0.12
5569 || orf19.1450 || || || Ortholog of C. dubliniensis CD36 : Cd36_16320, Candida tropicalis MYA-3404 : CTRG_01238 and Candida albicans WO-1 : CAWG_03918 || 1 -1.25 0.32 0.48 2.86 -0.76 -1.44 -0.37 0.50 -1.29 0.53 -0.32 -1.98 0.03 0.81 0.49
5570 || orf19.994 || || || Protein of unknown function; induced by Mnl1 under weak acid stress; flow model biofilm repressed || 1 0.25 -0.20 0.35 2.00 -0.31 -1.73 0.28 0.61 -0.49 -0.29 0.25 -0.77 -0.19 0.02 -0.33 0.65
5571 || orf19.5677 || DUR4 || || Putative urea permease; fungal-specific (no human or murine homolog); possibly an essential gene, disruptants not obtained by UAU1 method || 1 -0.32 0.14 -0.33 2.61 -0.12 -1.23 0.83 0.86 -0.42 -1.38 0.20 0.08 0.34 0.97 1.15
5572 || orf19.1821 || || || Protein of unknown function; repressed by alpha pheromone in SpiderM medium || 1 0.80 -0.11 -0.26 2.20 0.22 0.57 0.39 -0.21 -0.35 0.18 -1.36 0.47 0.70 -0.10
5573 || orf19.2211 || || || Ortholog of C. dubliniensis CD36 : Cd36_21990, C. parapsilosis CDC317 : CPAR2_103660, Debaryomyces hansenii CBS767 : DEHA2F19756g and Pichia stipitis Pignal : PICST_61375 || 1 0.54 -0.10 -0.40 0.08 0.69 0.49 -0.35 -0.25 -0.42 -0.95 0.27 0.94 0.36 -0.21
5574 || orf19.6897 || || || Protein of unknown function || 1 -0.05 0.08 0.41 0.70 0.57 -0.19 0.13 0.93 -0.08 -0.08 -0.17 -0.46 0.38 -0.25 0.02 -0.69
5575 || orf19.4104 || || || Ortholog of C. dubliniensis CD36 : Cd36_20540, C. parapsilosis CDC317 : CPAR2_104860, Candida tenuis NRRL Y-1498 : CANTEDRAFT_116071 and Pichia stipitis Pignal : PICST_32327 || 1 0.40 0.13 0.60 0.52 0.46 -0.01 0.74 0.61 -0.22 -0.66 -0.19 -0.37 0.12 -0.76 0.05 -0.04
5576 || orf19.26 || || || Putative peptide N-glycanase; induced by nitric oxide independent of Yhb1p || 1 0.22 0.03 0.89 1.04 0.10 0.33 0.37 0.33 0.06 -1.05 -0.04 -0.42 0.13 -0.75 0.29 -0.20
5577 || orf19.6562 || RNH35 || || Putative ribonuclease H2 catalytic subunit; flucytosine induced; Spider biofilm repressed || 1 0.03 -0.01 0.57 0.84 -0.13 0.06 0.18 0.26 0.06 -0.54 -0.26 -0.34 -0.06 -0.08 -0.10 -0.41
5578 || orf19.2383 || YKU80 || || Yku70p-Yku80p Ku complex subunit involved in nonhomologous end joining during double-strand break repair repair; Hap43-repressed gene; flow model biofilm induced || 1 -0.09 0.07 0.41 0.06 0.06 -0.34 -0.03 0.05 0.08 -0.54 -0.23 -0.29 0.14 0.14 -0.08 -0.31
5579 || orf19.3058 || COQ6 || || Ortholog(s) have role in ubiquinone biosynthetic process and mitochondrial inner membrane localization || 1 -0.03 -0.10 0.51 -0.08 -0.01 -0.22 0.21 0.29 0.25 -0.43 -0.18 -0.14 -0.25 -0.11 0.00 -0.05
5580 || orf19.1162 || || || Protein of unknown function; transcript upregulated by benomyl treatment || 1 0.01 -0.21 0.06 -0.22 -0.49 -0.31 0.78 0.34 0.24 -0.58 0.16 -0.57 -0.07 -0.44 0.01 -0.58
5581 || orf19.5484 || SER1 || || Putative 3-phosphoserine aminotransferase; predicted role in serine and glycine biosynthesis; protein present in exponential and stationary yeast growth phases; Spider biofilm repressed || 1 0.02 -0.04 0.07 -0.24 -0.08 -0.24 0.27 0.07 0.46 -0.58 0.03 0.02 -0.08 -0.55 -0.05 -0.22
5582 || orf19.4736 || || || Ortholog(s) have alkaline phosphatase activity and role in cellular response to cadmium ion, detoxification of cadmium ion, nicotinamide nucleotide metabolic process, protein dephosphorylation || 1 0.46 0.51 0.06 -0.20 -0.16 -0.36 0.61 0.07 0.15 -0.35 0.02 -0.03 -0.20 -0.64 -0.26 -0.45
5583 || orf19.2713 || || || Ortholog(s) have role in reciprocal meiotic recombination and nucleus localization || 1 0.14 -0.12 0.22 0.53 0.01 0.19 0.80 -0.08 0.09 -0.05 -0.49 0.19 -0.52 -0.27 -0.34 -0.30
5584 || orf19.3443 || OYE2 || || Putative NAPDH dehydrogenase; induced by nitric oxide; Spider biofilm induced || 1 0.25 0.15 0.42 0.51 -0.60 0.16 0.61 0.12 -0.10 -0.47 -0.69 -0.01 -0.45 -0.53 -0.29 -0.42
5585 || orf19.513 || || || Protein with a DNA-binding domain, similar to S. cerevisiae meiosis-specific transcription factor Ndt80p || 1 -0.47 -0.02 0.77 0.41 -0.70 0.17 -0.11 0.03 0.78 0.48 -0.33 0.05 -0.26 0.29 -0.39
5586 || orf19.819 || || || Ortholog(s) have role in lipoate biosynthetic process and mitochondrion localization || 1 -0.12 -0.17 0.51 0.86 -0.46 -0.14 -0.13 -0.05 0.36 0.37 -0.63 -0.14 -0.38 -0.73 -0.08 -0.17
5587 || orf19.6100 || || || Cardiolipin synthase; ortholog of S. cerevisiae Crd1; transcript is upregulated in clinical isolates from HIV+ patients with oral candidiasis; mutants are viable; Spider biofilm repressed || 1 -0.32 -0.16 0.15 0.17 -0.22 0.14 -0.54 -0.14 0.28 0.08 -0.28 -0.22 -0.14 -0.83 -0.33 -0.39
5588 || orf19.3103 || || || Ortholog(s) have RNA polymerase III activity, role in tRNA transcription from RNA polymerase III promoter and DNA-directed RNA polymerase III complex, cytoplasm localization || 1 0.13 0.17 0.10 0.20 0.31 0.52 -0.09 0.02 0.13 0.20 -0.24 0.08 -0.77 -0.90 -0.45 -0.14
5589 || orf19.4099 || ECM17 || || Putative sulfite reductase beta subunit; role in cell wall biogenesis; regulated by Tsa1/Tsa1B in H2O2 stress; Gcn4-regulated; Tbf1-activated; Hap43-repressed; Spider, flow, F-12/CO2 model biofilm induced || 1 0.25 0.30 0.46 0.83 -0.20 1.00 -0.22 0.09 -0.05 0.14 -0.44 -0.23 -1.73 -1.54 0.21 -0.46
5590 || orf19.4099 || ECM17 || || Putative sulfite reductase beta subunit; role in cell wall biogenesis; regulated by Tsa1/Tsa1B in H2O2 stress; Gcn4-regulated; Tbf1-activated; Hap43-repressed; Spider, flow, F-12/CO2 model biofilm induced || 1 0.31 0.38 0.06 0.43 0.06 0.60 -0.11 0.08 -0.35 0.06 -0.41 -1.27 -2.28 -2.35 -0.00 -1.51
5591 || orf19.6257 || GLT1 || || Putative glutamate synthase; regulated by Sef1, Sfu1, and Hap43; rat catheter biofilm repressed || 1 -0.43 -0.47 0.03 0.46 -0.61 -0.46 0.09 -0.16 0.05 -0.18 0.00 0.31 -1.46 -1.98 0.14 -0.33
5592 || orf19.6257 || GLT1 || || Putative glutamate synthase; regulated by Sef1, Sfu1, and Hap43; rat catheter biofilm repressed || 1 -0.40 -0.41 0.50 0.71 -0.67 -0.23 0.03 -0.06 0.26 0.19 0.00 0.49 -1.06 -1.64 0.26 -0.73
5593 || orf19.6257 || GLT1 || || Putative glutamate synthase; regulated by Sef1, Sfu1, and Hap43; rat catheter biofilm repressed || 1 0.17 0.10 0.63 1.25 -0.59 -0.04 0.35 0.29 0.43 0.31 0.01 0.44 -1.01 -1.80 0.30 -0.55
5594 || orf19.6257 || GLT1 || || Putative glutamate synthase; regulated by Sef1, Sfu1, and Hap43; rat catheter biofilm repressed || 1 -0.01 0.08 0.41 0.84 -0.21 -0.00 -0.26 -0.41 0.25 0.01 -0.09 0.57 -0.56 -1.51 0.35 -0.22
5595 || orf19.3196 || || || Ortholog of Candida albicans WO-1 : CAWG_04564 || 1 0.02 0.19 0.57 0.98 -0.08 0.30 -0.53 -0.18 0.23 -0.17 0.10 0.08 -0.86 -1.26 0.02 0.14
5596 || orf19.4320 || || || Ortholog of Candida albicans WO-1 : CAWG_04676 || 1 0.25 -0.10 0.74 0.55 0.22 -0.13 -0.44 -0.07 0.25 -0.14 0.42 0.42 -0.51 -1.74 0.41 0.37
5597 || orf19.2938 || || || Putative mitochondrial inner membrane protein with a predicted role in the assembly of respiratory complex III; Hap43p-repressed gene; S. cerevisiae ortholog FMP25 localizes to mitochondrion || 1 0.51 0.31 0.23 0.20 -0.01 0.13 0.15 -0.03 0.27 0.54 -0.12 0.67 -0.77 -0.36 0.22 -0.17
5598 || orf19.637 || SDH2 || || Succinate dehydrogenase, Fe-S subunit; localizes to surface of yeast cells, but not hyphae; induced in high iron and during log phase aerobic growth; repressed by nitric oxide, Hap43 || 1 0.53 0.52 -0.02 -0.25 -0.21 -0.09 0.40 0.43 0.29 0.45 0.29 0.58 -1.26 -0.95 0.04 -0.41
5599 || orf19.5194.1 || || || Putative protein of unknown function; clade-associated gene expression || 1 0.56 0.26 0.21 0.10 -0.31 -0.26 0.39 0.09 0.08 0.11 -0.14 0.07 -0.80 -0.69 -0.84 -0.30
5600 || orf19.125 || EBP1 || || NADPH oxidoreductase; interacts with phenolic substrates (17beta-estradiol); possible role in estrogen response; induced by oxidative, weak acid stress, NO, benomyl, GlcNAc; Cap1, Mnl1 induced; Hap43-repressed; rat catheter biofilm induced || 1 0.36 0.24 0.37 0.03 -0.23 0.39 0.64 0.22 0.58 -0.29 0.09 0.47 -0.68 -0.92 -0.52 0.06
5601 || orf19.489 || DAP1 || || Similar to mammalian membrane-associated progesterone receptors involved in DNA damage response; induced in core stress response; Hog1 regulated; clade-associated expression; Hap43-repressed || 1 0.80 0.75 0.04 -0.10 0.09 0.03 0.45 0.98 0.75 -0.29 0.28 0.25 -1.07 -0.82 -1.46 0.12
5602 || orf19.489 || DAP1 || || Similar to mammalian membrane-associated progesterone receptors involved in DNA damage response; induced in core stress response; Hog1 regulated; clade-associated expression; Hap43-repressed || 1 0.67 0.52 0.32 0.19 0.02 0.07 0.22 0.72 0.59 -0.46 0.12 0.01 -0.66 -1.11 -0.75 -0.05
5603 || orf19.5438 || || || Putative ubiquitin-protein ligase; role in protein sumoylation, protein ubiquitination; Spider biofilm induced || 1 0.51 0.63 0.43 0.50 0.10 0.41 -0.02 0.22 0.42 -0.23 0.48 -0.06 -0.50 -0.56 -0.95 -0.03
5604 || orf19.279 || || || Protein with a predicted D-Tyr-tRNA(Tyr) deacylase domain; Hap43-repressed gene || 1 0.03 0.21 -0.10 0.08 -0.20 0.00 0.19 0.53 -0.00 0.20 0.43 -0.26 -0.48 -0.63 -0.34 -0.35
5605 || orf19.297 || DTD2 || || Ortholog(s) have D-leucyl-tRNA(Leu) deacylase activity, D-tyrosyl-tRNA(Tyr) deacylase activity, role in D-leucine catabolic process, D-tyrosine catabolic process, tRNA metabolic process and cytosol, nucleus localization || 1 -0.02 -0.03 -0.03 -0.11 -0.07 0.02 0.41 0.65 0.17 0.19 0.34 -0.22 -0.76 -0.29 0.11 -0.17
5606 || orf19.423 || || || Ortholog(s) have enzyme activator activity, m7G(5')pppN diphosphatase activity, mRNA binding activity, role in deadenylation-dependent decapping of nuclear-transcribed mRNA and cytoplasmic mRNA processing body localization || 1 0.14 0.36 -0.38 0.21 -0.28 -0.38 -0.17 0.25 -0.17 0.15 0.32 -0.13 -0.43 -0.26 0.01 -0.15
5607 || orf19.6990 || || || Putative peptidyl-prolyl cis-trans isomerase; predicted endoplasmic reticulum (ER) localization || 1 -0.15 -0.10 0.00 -0.14 0.09 -0.48 0.12 0.32 0.16 0.01 0.03 0.08 -0.17 -0.33 -0.24 -0.11
5608 || orf19.1648 || RAD50 || || Putative DNA double-strand break repair factor; involved in response to oxidative stress and drug resistance; flow model biofilm repressed || 1 -0.25 -0.03 -0.26 -0.09 0.48 -0.87 -0.05 0.19 -0.08 0.10 0.12 -0.29 -0.37 -0.75 -0.03 -0.26
5609 || orf19.3031 || SEC62 || || Putative endoplasmic reticulum (ER) protein-translocation complex subunit || 1 -0.08 -0.14 0.06 0.17 -0.06 -0.77 0.05 0.30 -0.14 0.38 -0.09 -0.12 -0.11 -0.54 0.20 -0.06
5610 || orf19.5851 || STE13 || || Putative pheromone-processing dipeptidyl aminopeptidase; possible Kex2 substrate; transposon mutation affects filamentous growth; induced by low nitrogen, germ tube formation; flow model biofilm repressed || 1 0.09 -0.36 -0.38 0.23 -0.01 -0.61 0.06 0.12 -0.23 0.17 0.18 -0.06 -0.42 -0.69 -0.08 0.25
5611 || orf19.4227 || || || Ortholog of C. parapsilosis CDC317 : CPAR2_100400, C. dubliniensis CD36 : Cd36_52020, Debaryomyces hansenii CBS767 : DEHA2F14278g and Candida orthopsilosis Co 90-125 : CORT_0F00500 || 1 -0.03 -0.06 0.11 -0.12 -0.25 -0.50 0.18 0.32 -0.58 0.02 0.02 0.05 -0.69 -1.35 0.45 0.15
5612 || orf19.5970 || || || Putative DNA repair helicase; transcriptionally induced by interaction with macrophage; fungal-specific (no human or murine homolog) || 1 0.21 0.18 0.01 -0.13 -0.24 -0.40 -0.00 0.04 -0.04 0.00 -0.21 -0.18 -0.25 -0.51 0.18 0.36
5613 || orf19.2624 || || || Protein of unknown function; downregulated by fluphenazine treatment or in an azole-resistant strain that overexpresses CDR1 and CDR2 || 1 -0.04 -0.05 -0.10 0.10 0.10 -0.34 0.13 0.20 -0.30 0.47 -0.56 -0.00 -0.46 0.01 -0.07
5614 || orf19.4495 || NDH51 || || Nicotinamide adenine dinucleotide dehydrogenase complex I subunit of the mitochondrial electron transport chain; required for wild-type filamentous growth; alkaline repressed; Hap43-repressed; Spider biofilm repressed || 1 0.57 0.50 0.05 -0.08 -0.36 -0.07 0.09 0.32 -0.18 0.53 -0.59 -0.08 -0.77 -0.09 -0.16 -0.72
5615 || orf19.3801 || FAV1 || || Protein with weak similarity to S. cerevisiae Fus2p; induced by alpha pheromone mating factor in MTLa/MTLa opaque cells || 1 0.26 0.10 -0.15 -0.55 0.04 -0.64 0.02 1.38 -0.08 1.00 -0.06 -0.45 -0.04 -0.07 -0.46
5616 || orf19.937 || || || Ortholog of Candida albicans WO-1 : CAWG_04446 || 1 0.26 0.62 -0.57 -0.06 0.02 -0.13 0.13 0.28 0.51 0.66 0.37 -0.16 -0.09 -0.73 -0.11 0.10
5617 || orf19.5064 || MRPL3 || || Ribosomal protein of the large subunit, mitochondrial; repressed in core stress response; protein present in exponential and stationary growth phase yeast cultures || 1 -0.02 0.00 -0.15 -0.11 0.14 -0.01 0.04 0.34 0.25 0.67 0.19 0.60 0.33 -0.61 0.34 -0.31
5618 || orf19.4022 || SDH4 || || Succinate dehydrogenase, membrane subunit; induced in high iron || 1 0.05 -0.12 -0.10 0.16 0.20 -0.14 -0.17 0.57 0.25 0.88 0.29 0.27 -0.21 -0.59 -0.03 -0.14
5619 || orf19.304 || || || Putative transporter similar to MDR proteins; fungal-specific; Spider biofilm induced || 1 0.23 0.02 -0.52 0.17 0.10 0.31 -0.01 0.41 0.16 0.57 -0.02 0.52 -0.27 -0.89 0.27 0.04
5620 || orf19.5264 || || || Dubious open reading frame || 1 0.06 0.33 0.17 0.17 0.44 0.34 0.39 0.03 0.66 -0.51 -0.04 -0.32 -0.78 0.55 -0.35
5621 || orf19.2091 || || || Putative NADH dehydrogenase; repressed by nitric oxide, Hap43p-repressed || 1 0.53 0.47 0.29 0.03 0.38 0.05 0.70 0.97 0.64 1.07 -0.01 -0.07 -0.63 -0.53 0.01 -0.37
5622 || orf19.2091 || || || Putative NADH dehydrogenase; repressed by nitric oxide, Hap43p-repressed || 1 0.47 0.36 -0.24 -0.17 0.48 -0.37 0.75 0.96 0.49 0.75 -0.28 -0.37 -0.42 -0.41 0.12 -1.16
5623 || orf19.4007 || || || Ortholog(s) have protein-lysine N-methyltransferase activity, role in peptidyl-lysine monomethylation, peptidyl-lysine trimethylation and cytosol, nucleolus localization || 1 0.22 -0.14 -0.51 -0.15 0.37 0.06 0.49 0.49 0.45 0.25 -0.40 0.01 -0.23 -0.05 0.20 -0.30
5624 || orf19.2363 || || || Ortholog(s) have thiosulfate sulfurtransferase activity and mitochondrion localization || 1 0.05 -0.05 -0.30 -0.18 0.23 0.19 0.29 0.55 0.83 0.60 0.20 0.04 0.01 -0.32 0.44 -0.04
5625 || orf19.863 || || || Ortholog(s) have structural constituent of ribosome activity and mitochondrial large ribosomal subunit localization || 1 0.03 0.04 -0.04 0.14 0.37 0.10 0.25 0.47 0.64 0.69 0.27 -0.02 0.33 -0.31 0.20 -0.55
5626 || orf19.7518 || ZCF38 || || Putative Zn(II)2Cys6 transcription factor || 1 -0.18 -0.30 0.19 0.28 0.88 0.43 0.12 0.43 1.28 0.38 -0.29 -0.24 0.16 -0.20 0.25 -0.50
5627 || orf19.1227 || ZCF4 || || Putative Zn(II)2Cys6 transcription factor || 1 0.24 0.23 -0.23 2.35 0.45 0.38 0.36 0.38 0.90 0.47 0.05 1.41 -1.61 0.96 -1.06
5628 || orf19.3517 || || || Ortholog(s) have Dsc E3 ubiquitin ligase complex, endoplasmic reticulum, fungal-type vacuole lumen localization || 1 0.12 0.38 0.02 0.96 0.35 0.02 -0.22 0.06 0.01 -0.19 0.28 0.06 0.30 -0.60 0.17 -0.36
5629 || orf19.1958 || || || Dubious open reading frame || 1 -0.25 -0.32 0.25 1.72 0.30 -0.78 -0.25 -0.50 0.39 -1.23 -0.11 0.65 0.57 -0.43 -0.16 -0.80
5630 || orf19.6200 || || || Pry family pathogenesis-related protein; oral infection upregulated gene; mutant has reduced capacity to damage oral epithelial cells || 1 0.11 0.25 -0.59 1.46 -0.05 0.11 -0.47 -0.61 0.42 -0.55 -0.80 -0.21 0.24 -0.95 -0.44 -0.89
5631 || orf19.53 || || || Ortholog(s) have role in generation of catalytic spliceosome for first transesterification step, mRNA cis splicing, via spliceosome and commitment complex, cytosol localization || 1 0.03 0.02 -0.74 0.52 0.04 0.05 -0.26 -0.12 0.04 -0.55 -0.19 -0.00 0.20 -0.34 -0.01 -0.61
5632 || orf19.7208 || CSK1 || || Putative mitogen-activated protein (MAP) kinase with an unknown role; null mutant produces wrinkled colonies; similar to S. cerevisiae Smk1p, which is a protein kinase required for sporulation || 1 -0.49 -0.68 -1.39 1.28 0.30 -0.08 -0.47 -0.51 -0.41 -1.02 0.50 -0.02
5633 || orf19.2906 || PGA41 || || Putative GPI-anchored protein; adhesin-like protein || 1 0.16 0.09 -0.70 0.48 -0.30 -0.26 -0.40 -0.10 0.10 -0.56 -0.56 -0.27 -0.01 -0.46 0.68 0.08
5634 || orf19.778 || PIL1 || || Eisosome component; predicted role in endocytosis; echinocandin-binding protein; localizes to cell surface of hyphae, but not yeast-form cells; Hap43, YNB biofilm induced; rat catheter biofilm repressed || 1 0.03 -0.04 0.09 0.33 -0.70 0.04 -0.40 -0.21 0.29 -0.46 0.11 -0.03 0.49 -0.61 0.73 -0.19
5635 || orf19.1318 || || || Ortholog of C. dubliniensis CD36 : Cd36_43350, C. parapsilosis CDC317 : CPAR2_403560, Debaryomyces hansenii CBS767 : DEHA2A08250g and Pichia stipitis Pignal : PICST_29838 || 1 0.22 0.10 0.08 -0.14 -0.12 0.08 0.02 -0.04 -0.20 0.16 0.04 0.11 0.08 -0.19 0.30 -0.24
5636 || orf19.4017 || || || Ortholog of C. dubliniensis CD36 : Cd36_54840, C. parapsilosis CDC317 : CPAR2_100270, Candida tenuis NRRL Y-1498 : cten_CGOB_00242 and Debaryomyces hansenii CBS767 : DEHA2D14058g || 1 0.29 -0.48 0.63 -0.18 0.07 0.07 0.43 0.05 0.69 -0.17 -0.07 0.22 0.43 -0.97 0.38 -1.15
5637 || orf19.2430 || || || Ortholog of Candida albicans WO-1 : CAWG_00792 || 1 0.18 0.05 -0.19 0.16 0.08 -0.41 -0.07 -0.05 0.20 0.05 -0.44 0.01 -0.19 -0.84 0.51 -0.74
5638 || orf19.4366 || || || Ortholog of C. dubliniensis CD36 : Cd36_28870, Candida tropicalis MYA-3404 : CTRG_00731 and Candida albicans WO-1 : CAWG_01703 || 1 0.07 -0.12 0.05 0.03 -0.01 -0.12 -0.05 -0.66 0.39 0.36 -0.58 0.02 -0.01 -2.00 0.75 -1.85
5639 || orf19.3172 || || || Ortholog of C. dubliniensis CD36 : Cd36_51840, Candida tropicalis MYA-3404 : CTRG_05315 and Candida albicans WO-1 : CAWG_04584 || 1 0.51 0.41 0.16 0.42 -0.29 -0.28 0.42 -0.39 -0.21 0.74 -0.35 0.09 0.55 -1.38 0.48 -0.50
5640 || orf19.723 || BCR1 || || Transcription factor; regulates a/alpha biofilm formation, matrix, cell-surface-associated genes; confers adherence, impermeability, impenetrability, fluconazole resistance; Tup1/Tec1/Mnl1-regulated; mRNA binds She3; Spider biofilm induced || 1 0.76 0.47 0.15 0.35 -0.04 -0.42 0.29 -0.23 0.15 0.13 -0.28 -0.51 0.77 -0.34 0.70 -1.02
5641 || orf19.723 || BCR1 || || Transcription factor; regulates a/alpha biofilm formation, matrix, cell-surface-associated genes; confers adherence, impermeability, impenetrability, fluconazole resistance; Tup1/Tec1/Mnl1-regulated; mRNA binds She3; Spider biofilm induced || 1 0.26 0.11 -0.21 0.30 -0.28 -0.45 0.47 -0.28 0.03 0.50 -0.73 -0.65 0.67 -0.24 0.71 -0.72
5642 || orf19.7648 || || || Has domain(s) with predicted antiporter activity, drug transmembrane transporter activity, role in drug transmembrane transport and membrane localization || 1 0.12 0.77 0.17 0.21 0.69 -0.43 -0.30 -0.50 0.14 -0.24 -0.26 0.57 0.84 -0.48 0.37 -0.47
5643 || orf19.2312 || || || Protein similar to ferric reductase Fre10p; possibly an essential gene, disruptants not obtained by UAU1 method || 1 0.07 0.30 0.45 0.35 0.96 -1.40 0.45 0.11 1.41 -0.20 0.17 0.86 0.17 -1.82 -0.12 -0.97
5644 || orf19.4332 || || || Ortholog of C. dubliniensis CD36 : Cd36_52800, C. parapsilosis CDC317 : CPAR2_303110, Candida tenuis NRRL Y-1498 : CANTEDRAFT_92321 and Debaryomyces hansenii CBS767 : DEHA2G07964g || 1 -0.15 -0.24 -0.31 -0.18 -0.49 -0.56 0.01 -0.17 0.26 0.03 -0.04 0.09 0.23 -0.53 -0.16 -0.44
5645 || orf19.1685 || ZCF7 || || Predicted Zn(II)2Cys6 transcription factor; mutant shows reduced colony wrinkling on Spider medium and is unable to utilize mannitol as a carbon source; mutants have increased colonization of mouse kidneys || 1 0.22 -0.03 -0.25 -0.24 -0.47 -1.16 -0.03 -0.12 0.20 -0.01 0.01 0.08 0.62 -0.80 -0.34 -0.88
5646 || orf19.4861.1 || || || Protein of unknown function || 1 0.30 0.14 -0.05 -0.87 -0.40 -0.29 -0.53 0.23 -0.14 -0.24 -0.30 0.56 -0.91 -0.06 -0.53
5647 || orf19.3522 || || || Protein of unknown function; flow model biofilm induced; transcript repressed by ciclopirox olamine || 1 0.69 -0.08 -0.52 -0.23 -0.37 -0.39 -0.41 -0.64 -0.17 0.62 -0.47 -1.53
5648 || orf19.7002 || || || Ortholog of C. parapsilosis CDC317 : CPAR2_806990, Candida tenuis NRRL Y-1498 : CANTEDRAFT_122709, Debaryomyces hansenii CBS767 : DEHA2E00110g and Pichia stipitis Pignal : PICST_30109 || 1 1.06 0.35 -0.81 -0.87 0.01 -0.47 -1.49 -0.36 -0.10 -1.04 -0.07 -0.06 -0.52 -1.83 -0.58 -1.14
5649 || orf19.5129 || || || Ortholog of C. dubliniensis CD36 : Cd36_72910, C. parapsilosis CDC317 : CPAR2_704100, Candida tenuis NRRL Y-1498 : CANTEDRAFT_113193 and Debaryomyces hansenii CBS767 : DEHA2E23100g || 1 0.40 0.20 0.35 0.61 -0.13 -0.20 -1.29 -0.37 -0.02 -0.36 0.24 0.22 -1.12 -0.65 -0.00 0.14
5650 || orf19.305 || || || Protein of unknown function; upregulated in a cyr1 null mutant || 1 -0.39 -0.51 0.22 0.30 0.05 -0.80 -0.26 -0.01 0.72 0.44 -0.04 -0.10 -0.23 0.25 -0.03 0.19
5651 || orf19.3673 || || || Ortholog(s) have Rab guanyl-nucleotide exchange factor activity, role in ER to Golgi vesicle-mediated transport, chromosome organization and TRAPP complex, cytosol, nucleus localization || 1 -0.14 -0.20 0.16 0.50 -0.37 -0.52 -0.34 -0.07 -0.08 0.32 0.12 0.11 -0.15 0.48 -0.09 0.04
5652 || orf19.5342 || || || Ortholog(s) have cytosol, extracellular region, fungal-type vacuole, nucleus localization || 1 -0.24 -0.33 0.22 0.49 -0.41 -0.63 -0.02 0.03 0.03 0.06 -0.20 -0.09 -0.38 0.12 0.13 0.01
5653 || orf19.5978 || || || Has domain(s) with predicted oxidoreductase activity, transferase activity, transferring acyl groups other than amino-acyl groups, zinc ion binding activity and role in oxidation-reduction process || 1 -0.29 0.16 0.41 0.73 -0.65 -1.94 -0.47 -0.59 0.02 0.01 -0.83 0.32 -0.38 0.43 1.14 0.56
5654 || orf19.5734 || POP2 || || Component of the Ccr4-Pop2 mRNA deadenylase; heterozygous null mutant exhibits resistance to parnafungin and cordycepin in the C. albicans fitness test || 1 -0.46 -0.28 0.15 0.28 -0.16 -0.24 -0.14 -0.22 0.02 0.09 0.14 0.41 0.20 -0.06 0.20 -0.05
5655 || orf19.203 || STB3 || || Putative SIN3-binding protein 3 homolog; caspofungin induced; macrophage/pseudohyphal-repressed; rat catheter biofilm induced || 1 -0.58 -0.55 0.09 1.25 0.41 -0.91 -0.86 -1.22 -0.46 0.04 0.35 0.60 0.44 -0.46 1.35 0.04
5656 || orf19.203 || STB3 || || Putative SIN3-binding protein 3 homolog; caspofungin induced; macrophage/pseudohyphal-repressed; rat catheter biofilm induced || 1 -0.88 -0.87 0.08 1.36 -0.20 -1.04 -1.36 -1.65 -0.93 -0.43 -0.15 0.15 -0.17 -0.70 0.66 -0.21
5657 || orf19.203 || STB3 || || Putative SIN3-binding protein 3 homolog; caspofungin induced; macrophage/pseudohyphal-repressed; rat catheter biofilm induced || 1 -1.13 -1.03 0.04 1.21 -0.26 -1.11 -1.27 -1.58 -0.89 -0.38 -0.13 0.25 -0.35 -0.81 0.79 0.34
5658 || orf19.5026 || || || C2H2 transcription factor; Spider biofilm induced || 1 -0.43 -0.47 0.05 0.55 -0.35 -0.38 -0.27 -0.65 -0.01 -0.12 -0.03 0.25 -0.41 -0.11 0.61 -0.20
5659 || orf19.7115 || SAC7 || || Putative GTPase activating protein (GAP) for Rho1; repressed upon adherence to polystyrene; macrophage/pseudohyphal-repressed; transcript is upregulated in RHE model of oral candidiasis and in clinical oral candidiasis || 1 -0.83 -0.68 0.08 0.46 -0.86 0.18 -1.09 -1.25 -0.39 0.24 -0.60 0.15 0.07 -0.50 0.76 -0.57
5660 || orf19.7115 || SAC7 || || Putative GTPase activating protein (GAP) for Rho1; repressed upon adherence to polystyrene; macrophage/pseudohyphal-repressed; transcript is upregulated in RHE model of oral candidiasis and in clinical oral candidiasis || 1 -0.44 -0.59 0.08 0.42 -0.60 0.08 -1.07 -1.15 -0.27 0.43 -0.73 0.05 0.18 -0.30 0.74 -0.44
5661 || orf19.2170 || PHM7 || || Putative transporter; fungal-specific; Hog1-repressed; repressed by 17-beta-estradiol, ethynyl estradiol; Hap43-induced; Spider biofilm induced || 1 -0.11 -0.16 -0.16 0.52 -0.63 -0.08 -0.61 -0.68 -0.03 0.29 -0.53 0.14 -0.14 -0.49 0.44 -0.55
5662 || orf19.7666 || || || Predicted membrane transporter, member of the anion:cation symporter (ACS) family, major facilitator superfamily (MFS) || 1 -0.20 -0.36 1.02 1.56 -0.60 0.30 -1.15 -1.62 0.10 -0.35 -1.23 -0.66 -1.92 -1.32 0.34 -0.14
5663 || orf19.355 || || || Has domain(s) with predicted oxidoreductase activity and role in oxidation-reduction process || 1 -0.19 0.26 1.13 1.25 -1.07 0.60 -1.56 -1.78 -1.27 -0.38 -2.04 -0.46 -1.80 -0.27 1.30 -0.17
5664 || orf19.355 || || || Has domain(s) with predicted oxidoreductase activity and role in oxidation-reduction process || 1 -0.17 -0.14 0.75 1.21 -0.60 0.41 -1.19 -1.37 -0.11 -0.25 -1.85 -0.47 -1.48 -0.25 1.64 -0.36
5665 || orf19.320 || || || Predicted short chain dehydrogenase; Spider biofilm induced || 1 -1.10 -1.11 0.38 0.97 -0.86 0.52 -1.37 -2.25 -0.46 -0.65 -1.89 0.03 -2.30 -0.99 2.46 0.37
5666 || orf19.320 || || || Predicted short chain dehydrogenase; Spider biofilm induced || 1 -1.78 -1.43 0.12 0.47 -1.14 0.29 -1.70 -2.48 -1.01 -0.91 -1.89 -0.17 -2.56 -1.02 1.82 0.22
5667 || orf19.6398 || || || S. pombe ortholog SPBC460.04c is a predicted sulfonate/alpha-ketoglutare dioxygenase; induced by nitric oxide; Spider biofilm induced || 1 -0.65 -0.71 0.19 0.35 -0.87 0.07 -1.11 -1.32 -0.04 -0.81 -1.49 -0.73 -0.91 -0.41 0.74 -0.15
5668 || orf19.1167 || || || Ortholog(s) have sulfonate dioxygenase activity and role in sulfur compound catabolic process || 1 -0.38 -0.38 -0.17 0.34 -1.20 -0.36 -0.44 -0.76 0.10 -0.18 -1.05 -0.21 -2.12 -0.83 0.78 0.13
5669 || orf19.6933 || || || Ortholog(s) have peptidyl-prolyl cis-trans isomerase activity, protein phosphatase type 2A regulator activity || 1 -0.37 -0.52 0.19 0.42 -0.53 -0.10 -0.17 -0.21 0.09 -0.07 -0.61 0.29 -0.45 -0.31 -0.09 -0.25
5670 || orf19.4335 || TNA1 || || Putative nicotinic acid transporter; detected at germ tube plasma membrane by mass spectrometry; transcript induced upon phagocytosis by macrophage; rat catheter biofilm induced || 1 -2.22 -2.34 0.46 1.38 -4.01 -1.32 -0.89 -2.04 0.47 0.62 -2.69 -0.13 -1.97 -1.61 1.44 -1.27
5671 || orf19.4335 || TNA1 || || Putative nicotinic acid transporter; detected at germ tube plasma membrane by mass spectrometry; transcript induced upon phagocytosis by macrophage; rat catheter biofilm induced || 1 -0.93 -0.87 0.55 1.14 -0.96 -0.68 -0.69 -1.73 0.15 -0.11 -1.94 -0.25 -0.99 -1.34 1.17 -0.97
5672 || orf19.1608 || || || Ortholog(s) have cytosol, nucleus localization || 1 -0.80 -0.78 0.00 0.96 -0.71 -0.15 -0.54 -0.71 0.51 -0.00 -1.51 -0.35 -0.55 0.13 1.29 -0.25
5673 || orf19.4114 || FAA2-1 || || Predicted long chain fatty acid CoA ligase; upregulated upon phagocytosis; induced by nitric oxide independent of Yhb1 || 1 -0.57 -0.78 0.11 0.13 -0.11 0.16 -0.40 -0.28 -0.04 0.07 -0.93 -0.41 -0.96 -0.17 0.46 -0.42
5674 || orf19.7364 || || || Has domain(s) with predicted N,N-dimethylaniline monooxygenase activity, NADP binding, flavin adenine dinucleotide binding activity and role in oxidation-reduction process || 1 -0.59 -0.81 1.10 1.20 -0.01 -0.54 -0.62 -0.17 0.00 -0.20 -1.58 -0.32 -0.81 -0.32 0.63 0.18
5675 || orf19.1167 || || || Ortholog(s) have sulfonate dioxygenase activity and role in sulfur compound catabolic process || 1 -0.29 -0.18 -0.11 0.97 -0.06 0.44 -0.55 -0.40 0.61 -0.22 -1.47 0.35 -1.07 -0.46 0.48 0.02
5676 || orf19.2151 || NAG6 || || Protein required for wild-type mouse virulence and wild-type cycloheximide resistance; putative GTP-binding motif; similar to S. cerevisiae Yor165Wp; in gene cluster that encodes enzymes of GlcNAc catabolism; no human or murine homolog || 1 -0.31 -0.16 0.31 0.01 -0.02 0.05 -0.36 -0.38 -0.04 -0.17 -0.44 -0.12 -0.63 -0.10 0.00 -0.03
5677 || orf19.7207 || DOA4 || || Ortholog of S. cerevisiae Doa4;, a ubiquitin hydrolase involved in recycling ubiquitin from proteasome-bound ubiquitinated intermediates; oxidative stress-induced via Cap1; mutants are viable || 1 -0.21 -0.47 0.61 0.34 -0.15 -0.21 -0.45 -0.58 -0.19 -0.58 -0.31 0.02 -1.07 -0.26 -0.12 0.31
5678 || orf19.3499 || || || Secreted potein; Hap43-repressed; fluconazole-induced; regulated by Tsa1, Tsa1B under H2O2 stress conditions; induced by Mnl1p under weak acid stress; Spider biofilm induced || 1 -0.41 -0.29 -0.09 1.32 -0.25 -0.23 -1.24 -2.51 -0.10 -1.41 -0.32 0.39 -2.20 -1.61 0.98 -0.10
5679 || orf19.3499 || || || Secreted potein; Hap43-repressed; fluconazole-induced; regulated by Tsa1, Tsa1B under H2O2 stress conditions; induced by Mnl1p under weak acid stress; Spider biofilm induced || 1 -0.37 -0.25 0.51 1.44 -1.37 -1.05 -1.29 -2.08 -0.08 -1.23 -0.29 0.46 -2.00 -1.69 1.08 0.64
5680 || orf19.3499 || || || Secreted potein; Hap43-repressed; fluconazole-induced; regulated by Tsa1, Tsa1B under H2O2 stress conditions; induced by Mnl1p under weak acid stress; Spider biofilm induced || 1 -0.12 -0.14 0.48 1.12 -1.53 -1.06 -1.36 -2.48 -0.04 -1.43 -0.50 0.58 -2.40 -1.54 1.17 0.81
5681 || orf19.3499 || || || Secreted potein; Hap43-repressed; fluconazole-induced; regulated by Tsa1, Tsa1B under H2O2 stress conditions; induced by Mnl1p under weak acid stress; Spider biofilm induced || 1 0.13 0.02 0.58 1.20 -0.35 -0.42 -0.47 -1.25 0.28 -0.89 -0.07 0.66 -1.00 -0.94 1.08 0.83
5682 || orf19.3499 || || || Secreted potein; Hap43-repressed; fluconazole-induced; regulated by Tsa1, Tsa1B under H2O2 stress conditions; induced by Mnl1p under weak acid stress; Spider biofilm induced || 1 0.26 0.27 0.78 1.10 -0.26 -0.33 -0.75 -1.08 0.35 -0.66 -0.20 0.39 -0.74 -0.84 0.80 0.27
5683 || orf19.3885 || || || Has domain(s) with predicted N-acetyltransferase activity; highly induced during chlamydospore formation in both C. albicans and C. dubliniensis || 1 0.54 -0.04 0.15 0.09 -0.95 -0.92 -0.06 0.08 -0.09 -0.08 -0.34 0.83 -0.39 -0.01 0.05 0.26
5684 || orf19.5046 || RAM1 || || Protein that acts in prenylation; transcription is alpha-factor induced; regulated in response to lovastatin and fluconazole; Hap43p-repressed gene || 1 -0.04 -0.10 0.08 -0.04 -0.15 -0.43 -0.25 -0.01 -0.05 0.50 0.41 0.33 0.03 -0.11 0.17 0.21
5685 || orf19.5322 || || || Ortholog(s) have phosphatidylinositol-3-phosphate binding activity and role in CVT pathway, autophagic vacuole assembly, peroxisome degradation, protein localization to pre-autophagosomal structure, vesicle organization || 1 -0.04 -0.24 0.20 0.14 -0.25 -0.15 -0.38 -0.01 -0.01 0.23 0.27 0.52 -0.02 -0.21 0.20 0.32
5686 || orf19.5322 || || || Ortholog(s) have phosphatidylinositol-3-phosphate binding activity and role in CVT pathway, autophagic vacuole assembly, peroxisome degradation, protein localization to pre-autophagosomal structure, vesicle organization || 1 -0.08 -0.40 -0.14 -0.15 -0.41 -0.27 -0.47 0.02 -0.28 0.25 0.26 0.37 -0.25 -0.29 0.14 0.26
5687 || orf19.6880 || COG4 || || Ortholog(s) have role in CVT pathway, macroautophagy, peroxisome degradation, retrograde transport, vesicle recycling within Golgi and Golgi transport complex, cell division site, cell tip, nucleus localization || 1 -0.13 -0.09 -0.15 0.00 -0.30 -0.37 -0.06 0.27 -0.05 -0.09 0.13 0.51 0.02 0.18 -0.06 0.68
5688 || orf19.5777 || || || Protein of unknown function; F-12/CO2 early biofilm induced || 1 -0.12 -0.26 -0.17 0.22 -0.75 -0.41 0.03 0.27 -0.22 0.02 0.24 0.39 -0.28 0.19 -0.10 0.54
5689 || orf19.5777 || || || Protein of unknown function; F-12/CO2 early biofilm induced || 1 -0.17 -0.43 -0.27 0.31 -0.72 -0.44 -0.44 0.02 -0.09 0.20 0.39 0.80 -0.60 0.07 -0.31 0.63
5690 || orf19.6582 || PRE10 || || Alpha7 (C8) subunit of the 20S proteasome; multiple phosphorylated residues; transcript induced upon filamentous growth; Spider biofilm repressed || 1 -0.27 -0.07 0.01 0.21 -0.50 -0.53 -0.13 -0.22 -0.05 0.05 -0.11 0.70 -0.43 0.11 0.27 0.49
5691 || orf19.5544 || SAC6 || || Fimbrin; actin filament bundling protein; transcript regulated by Nrg1 and Mig1; protein level decreases in stationary phase || 1 -0.50 -0.47 -0.35 -0.15 -0.62 -0.22 -0.11 -0.28 -0.37 -0.38 -0.14 0.56 -0.33 0.28 0.27 0.49
5692 || orf19.3306 || || || Ortholog(s) have four-way junction DNA binding activity, role in meiotic recombination checkpoint, synaptonemal complex assembly and lateral element localization || 1 -0.78 -0.46 -0.60 -0.76 -0.71 -0.37 -0.82 -0.83 -0.36 -0.22 1.12 -0.47 0.70 0.12 0.80
5693 || orf19.5971 || || || Ortholog of S. cerevisiae : MTC6, C. glabrata CBS138 : CAGL0I01892g, C. dubliniensis CD36 : Cd36_84990, C. parapsilosis CDC317 : CPAR2_405620 and Candida tenuis NRRL Y-1498 : CANTEDRAFT_99433 || 1 -0.23 -0.22 -0.20 0.01 -0.31 -0.61 -0.09 -0.21 -0.52 -0.36 0.04 0.23 -0.41 0.14 0.19 0.19
5694 || orf19.1577 || || || Has domain(s) with predicted sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity, zinc ion binding activity and role in regulation of transcription, DNA-dependent || 1 -0.29 -0.36 -0.26 -0.05 -0.69 -0.02 0.12 -0.11 -0.61 -0.17 0.34 -0.30 -0.08 0.11 0.39
5695 || orf19.7229 || IML2 || || Protein of unknown function; early-stage flow model biofilm induced; Hap43-repressed; Spider biofilm repressed || 1 -0.52 -0.67 -0.21 0.28 -0.02 -0.30 -0.47 -0.24 -0.23 -0.47 0.12 0.34 -0.68 -0.04 0.22 0.45
5696 || orf19.2884 || CDC68 || || Functional homolog of S. cerevisiae Cdc68, a transcription elongation factor; essential; possible drug target || 1 -0.45 -0.36 -0.28 0.13 -0.15 -0.14 -0.37 0.00 -0.36 0.06 0.33 0.49 -0.41 -0.16 -0.02 0.18
5697 || orf19.1780 || || || Has domain(s) with predicted catalytic activity || 1 -1.10 -0.82 -0.25 0.37 0.16 -0.23 0.07 -0.91 0.01 0.38 0.92 -0.89 -0.04 -0.24
5698 || orf19.3045 || || || Predicted aldehyde dehydrogenase domain; virulence-group-correlated expression || 1 -0.20 -0.14 0.04 0.03 -0.03 -0.21 -0.29 -0.08 -0.43 0.03 0.09 0.31 -0.06 -0.22 0.01 0.40
5699 || orf19.2370 || DSL1 || || Protein similar to S. cerevisiae Dsl1p, which is a member of the t-SNARE complex of the endoplasmic reticulum || 1 -0.00 0.01 -0.11 0.27 -0.11 -0.17 -0.32 -0.32 -0.62 -0.19 0.35 0.80 -0.31 0.02 0.23 0.67
5700 || orf19.1634 || || || Has domain(s) with predicted fatty-acyl-CoA binding activity || 1 -0.35 -0.22 0.01 -0.22 -0.04 -0.21 -0.73 -0.63 -0.72 -0.50 0.41 0.37 -0.60 -0.08 0.06 0.72
5701 || orf19.3647 || SEC8 || || Predicted subunit of the exocyst complex, involved in exocytosis; localizes to a crescent on the surface of the hyphal tip || 1 -0.24 -0.16 0.25 -0.18 0.19 -0.27 -0.06 -0.49 -0.39 -0.30 0.12 0.36 -0.25 0.07 -0.01 0.35
5702 || orf19.4466 || || || Ortholog(s) have palmitoyltransferase activity and role in ascospore formation, cellular response to cadmium ion, detoxification of cadmium ion, protein palmitoylation, protein targeting to membrane || 1 -0.46 -0.50 0.02 0.30 0.02 0.19 -0.12 -0.25 -0.35 -0.10 -0.39 0.51 -0.31 -0.68 -0.13 0.77
5703 || orf19.2366 || || || Has domain(s) with predicted DNA binding activity and role in DNA integration || 1 -0.32 -0.32 0.41 0.34 -0.22 -0.06 -0.24 -0.17 -0.47 -0.50 -0.29 0.42 -0.44 -0.26 0.02 0.82
5704 || orf19.776 || || || Ortholog(s) have role in meiotic sister chromatid cohesion, protein localization to chromosome, centromeric region, reciprocal meiotic recombination, synaptonemal complex assembly || 1 -0.37 -0.44 0.12 -0.94 0.03 -0.55 -0.51 -0.96 -1.31 0.68 -0.29 -0.55 -0.20 1.07
5705 || orf19.3795 || AGP3 || || Putative serine transporter; possible role in assimilation of sulfur; F-12/CO2 early biofilm induced || 1 -0.41 -0.50 0.17 0.68 -0.60 0.26 -0.43 -0.40 -0.54 0.09 -0.38 0.41 -0.75 -0.16 -0.07 0.76
5706 || orf19.3267 || || || Ortholog(s) have palmitoyltransferase activity and role in ascospore wall assembly, cortical actin cytoskeleton organization, establishment of cell polarity, protein palmitoylation, regulation of exocytosis, vacuole fusion, non-autophagic || 1 -0.40 -0.18 0.07 0.22 -0.10 0.39 -0.30 -0.47 -0.39 -0.25 0.34 0.98 -0.58 0.22 0.13 0.31
5707 || orf19.1780 || || || Has domain(s) with predicted catalytic activity || 1 -0.44 -0.28 0.08 -0.06 -0.54 0.73 -0.56 0.13 -0.17 -0.51 -0.28 1.19 -0.93 0.01 0.26
5708 || orf19.225 || || || Predicted 2-hydroxyacid dehydrogenase; Hap43-repressed gene || 1 -0.26 -0.26 0.20 0.48 -0.40 0.01 0.04 0.10 0.24 -0.83 -0.41 -0.12 -0.06 -0.25 -0.22 -0.05
5709 || orf19.2212 || || || Ortholog of C. dubliniensis CD36 : Cd36_21980, Debaryomyces hansenii CBS767 : DEHA2F19734g, Pichia stipitis Pignal : psti_CGOB_00208 and Spathaspora passalidarum NRRL Y-27907 : spas_CGOB_00029 || 1 -0.44 -0.24 0.42 0.73 -0.53 -0.32 -0.16 0.22 0.10 -0.60 -0.03 -0.06 -0.29 -0.36 -0.62 0.02
5710 || orf19.5463 || SEC6 || || Predicted subunit of the exocyst complex, involved in exocytosis; localizes to a crescent on the surface of the hyphal tip; Hap43p-repressed gene, overlaps orf19.5464 and orf19.5465 || 1 -0.22 -0.17 0.26 0.36 -0.27 -0.16 -0.31 -0.08 0.18 -0.38 0.08 0.21 -0.42 -0.50 -0.19 0.22
5711 || orf19.5665 || || || Ortholog(s) have D-arabinose 1-dehydrogenase [NAD(P)+] activity and role in dehydro-D-arabinono-1,4-lactone biosynthetic process || 1 -0.29 -0.45 0.08 0.05 -0.66 -0.40 -0.07 -0.00 0.08 -0.65 0.05 0.17 -0.22 -0.54 -0.10 -0.26
5712 || orf19.3027 || || || Putative DNA translocase; Spider biofilm repressed || 1 -0.14 -0.20 0.02 0.35 -0.39 -0.25 -0.09 -0.22 -0.16 -0.50 -0.05 0.01 -0.05 -0.41 0.10 -0.31
5713 || orf19.2040 || || || Ortholog(s) have oxidoreductase activity, acting on NAD(P)H activity, role in iron-sulfur cluster assembly, nitric oxide biosynthetic process, oxidation-reduction process and mitochondrion localization || 1 -0.19 -0.26 0.21 0.39 -0.44 -0.44 -0.16 0.07 -0.05 -0.17 -0.39 0.17 0.16 -0.44 -0.37 -0.21
5714 || orf19.4398 || || || Protein of unknown function; rat catheter biofilm induced || 1 -0.25 -0.19 0.15 0.36 -0.90 -0.15 -0.47 -0.29 -0.52 0.03 -0.31 0.30 -0.41 -0.81 -0.36 0.10
5715 || orf19.5259 || || || Ortholog of C. dubliniensis CD36 : Cd36_11290, C. parapsilosis CDC317 : CPAR2_805090, Pichia stipitis Pignal : PICST_28850 and Candida guilliermondii ATCC 6260 : PGUG_02709 || 1 -0.22 -0.25 0.13 0.28 -0.85 -0.36 -0.08 -0.38 -0.22 -0.48 -0.51 0.05 -0.27 -0.53 -0.69 0.00
5716 || orf19.5007 || ACT1 || || Actin; gene has intron; transcript regulated by growth phase, starvation; at polarized growth site in budding and hyphal cells; required for wild-type Cdc42 localization; unprocessed N terminus; Hap43-induced; Spider biofilm repressed || 1 -0.25 -0.22 0.07 0.27 -0.93 -0.44 -0.23 -0.49 0.00 -0.18 -0.23 0.15 -0.05 -0.17 -0.45 0.39
5717 || orf19.4398 || || || Protein of unknown function; rat catheter biofilm induced || 1 -0.18 -0.09 0.24 0.21 -0.93 -0.10 -0.46 -0.36 -0.11 0.13 -0.18 0.19 0.08 -0.16 -0.55 -0.01
5718 || orf19.4702 || || || Possible similarity to mutator-like element (MULE) transposase; flow model biofilm induced; expression regulated during planktonic growth || 1 -0.24 -0.16 0.26 0.08 -0.70 -0.66 -0.37 -0.20 -0.29 -0.40 0.18 -0.01 -0.06 -0.19 -0.56 -0.11
5719 || orf19.5258 || || || Protein of unknown function; induced by nitric oxide || 1 -0.14 0.10 0.31 0.14 -0.35 -0.47 -0.02 -0.17 -0.30 -0.26 -0.07 0.09 -0.15 -0.74 -0.18 -0.05
5720 || orf19.4723 || FAD1 || || Ortholog(s) have ATP binding, FMN adenylyltransferase activity, magnesium ion binding activity, role in FAD biosynthetic process and cytosol, nucleus localization || 1 0.13 0.15 -0.06 0.12 -0.61 -0.65 -0.14 -0.15 -0.32 -0.72 -0.17 0.38 -0.33 -0.69 -0.50 0.42
5721 || orf19.2169 || || || Ortholog of C. parapsilosis CDC317 : CPAR2_805720, C. dubliniensis CD36 : Cd36_22330, Lodderomyces elongisporus NRLL YB-4239 : LELG_02628 and Candida orthopsilosis Co 90-125 : CORT_0C03440 || 1 -0.49 -0.86 0.46 1.19 -0.58 -1.40 -0.49 -0.37 -1.06 0.23 0.14 0.85 -0.47 -0.29 -0.05
5722 || orf19.3903 || MRV3 || || Ortholog of Candida albicans WO-1 : CAWG_04793 || 1 -0.21 -0.16 0.21 0.74 -0.43 -0.56 -0.50 0.24 -0.66 -0.10 -0.13 -0.15 -0.44 -0.72 -0.25 0.44
5723 || orf19.7286 || RPN7 || || Subunit of the proteasome regulatory particle; regulated by Gcn2p and Gcn4p; protein present in exponential and stationary growth phase yeast cultures || 1 -0.13 -0.24 0.06 0.17 -0.44 -0.23 -0.31 -0.05 -0.55 -0.18 -0.01 0.02 -0.80 -0.46 0.25 0.21
5724 || orf19.5025 || MET3 || || ATP sulfurlyase; sulfate assimilation; repressed by Met, Cys, Sfu1, or in fluconazole-resistant isolate; Hog1, caspofungin, white phase-induced; induced on biofilm formation, even in presence of Met and Cys; Spider, F-12/CO2 biofilm induced || 1 -0.83 -0.95 0.71 1.78 -4.15 -3.19 -1.03 -0.63 -2.59 -0.52 0.63 0.58 -4.11 -4.19 0.72 0.12
5725 || orf19.946 || MET14 || || Putative adenylylsulfate kinase; predicted role in sulfur metabolism; possibly adherence-induced; protein present in exponential and stationary growth phase yeast; F-12/CO2 biofilm induced || 1 -0.89 -0.79 -0.20 0.79 -1.61 -0.89 -0.45 0.26 -0.96 0.34 1.32 1.17 -1.42 -1.58 0.07 0.22
5726 || orf19.946 || MET14 || || Putative adenylylsulfate kinase; predicted role in sulfur metabolism; possibly adherence-induced; protein present in exponential and stationary growth phase yeast; F-12/CO2 biofilm induced || 1 -0.77 -0.75 -0.14 0.98 -2.24 -0.68 -0.21 0.67 -0.84 0.36 1.41 1.19 -1.50 -1.91 0.46 0.37
5727 || orf19.1665 || MNT1 || || Alpha-1,2-mannosyl transferase; predicted type II Golgi membrane protein; adds 2nd mannose during cell-wall mannoprotein biosynthesis; required for wild-type virulence and adherence to epithelial cells; Hap43-induced || 1 -0.44 -0.53 -0.08 0.14 -1.10 -1.18 -0.25 0.43 -0.80 0.05 0.65 0.32 -0.18 -0.31 0.21 0.26
5728 || orf19.6131 || KSR1 || || 3-ketosphinganine reductase, catalyzes the second step in phytosphingosine synthesis || 1 -0.28 -0.50 -0.16 0.15 -0.62 -0.57 0.08 0.04 -0.24 0.23 0.01 -0.02 -0.32 0.04 -0.01 -0.03
5729 || orf19.7592 || FAA4 || || Predicted acyl CoA synthase || 1 0.07 0.03 -0.16 0.54 -0.39 -0.34 -0.36 -0.25 -0.64 0.14 0.23 0.12 -0.32 -0.07 -0.02 0.18
5730 || orf19.272 || FAA21 || || Predicted acyl CoA synthetase; upregulated upon phagocytosis; transcript regulated by Nrg1 and Mig1 || 1 0.11 0.14 -0.30 0.39 -0.53 -0.32 -0.27 -0.45 -0.75 -0.36 0.05 0.58 -0.76 0.01 -0.01 -0.16
5731 || orf19.1112 || BUD7 || || Ortholog(s) have role in Golgi to plasma membrane transport, fungal-type cell wall chitin biosynthetic process and cell division site, clathrin-coated vesicle, cytosol, exomer complex, nucleus, ribosome localization || 1 0.13 0.06 -0.17 -0.12 -0.49 -0.50 -0.34 -0.34 -0.40 -0.05 0.10 0.14 -0.58 0.31 -0.10 0.29
5732 || orf19.5660 || || || Ortholog(s) have ubiquitin-protein ligase activity, role in protein import into peroxisome matrix, protein ubiquitination and endoplasmic reticulum, peroxisomal membrane localization || 1 0.03 -0.09 -0.09 -0.15 -0.84 -1.02 -0.61 0.05 -0.42 -0.05 0.12 0.02 -0.62 0.36 -0.02 -0.12
5733 || orf19.1112 || BUD7 || || Ortholog(s) have role in Golgi to plasma membrane transport, fungal-type cell wall chitin biosynthetic process and cell division site, clathrin-coated vesicle, cytosol, exomer complex, nucleus, ribosome localization || 1 0.29 0.21 0.29 0.09 -0.42 -0.64 -0.23 -0.03 -0.36 0.20 0.24 0.12 -0.47 -0.01 -0.04 0.05
5734 || orf19.3706 || || || Has domain(s) with predicted oxidoreductase activity, zinc ion binding activity and role in oxidation-reduction process || 1 0.56 0.32 0.06 0.57 -0.71 -0.81 -0.24 -0.08 -0.93 -0.50 0.40 -0.11 -0.94 0.05 -0.27 0.13
5735 || orf19.6650 || || || Ortholog of C. dubliniensis CD36 : Cd36_30990, C. parapsilosis CDC317 : CPAR2_204660, Candida tenuis NRRL Y-1498 : CANTEDRAFT_104939 and Debaryomyces hansenii CBS767 : DEHA2G23760g || 1 0.38 0.09 0.04 -0.05 -0.37 -0.55 -0.62 -0.17 -0.50 -0.36 -0.19 0.02 -0.64 0.05 -0.06 -0.43
5736 || orf19.1403 || || || Ortholog(s) have ATP:ADP antiporter activity, calcium ion binding activity, role in ADP transport, ATP transport, mitochondrial transport and mitochondrion localization || 1 -0.13 -0.17 -0.14 -0.14 -0.41 -0.22 -0.22 -0.09 0.22 0.21 -0.28 0.40 -0.21 -0.29 -0.07 -0.40
5737 || orf19.4937 || CHS3 || || Major chitin synthase of yeast and hyphae; synthesizes short-chitin fibrils; Chs4-activated; transcript induced at yeast-hyphal transition; Chs1 and Chs2, but not Chs3, are inhibited by the protoberberine HWY-289; Spider biofilm induced || 1 -0.38 -0.44 0.18 -0.11 -0.38 -0.54 -0.52 -0.38 -0.29 0.90 -0.26 0.11 -0.38 0.12 -0.08 -0.12
5738 || orf19.6599.1 || || || Ortholog(s) have role in cytoplasmic translation and cytoplasm, nucleus localization || 1 -0.21 -0.03 -0.18 -0.04 -0.25 -0.23 -0.28 -0.13 -0.22 0.25 -0.17 0.05 -0.28 0.10 -0.10 -0.03
5739 || orf19.7010 || || || Ortholog(s) have cytosol, ubiquitin ligase complex localization || 1 -0.39 -0.15 -0.08 -0.33 -0.29 -0.43 -0.45 -0.33 0.10 0.24 -0.30 0.08 -0.26 0.26 -0.09 0.16
5740 || orf19.7195 || RAD6 || || Functional ortholog of S. cerevisiae Rad6; negative regulator of hyphal growth; required for wild-type UV resistance; acts in pathway with Efg1; ; transcript is UV-induced, slightly repressed during hyphal growth; gene has two introns || 1 -0.41 -0.60 -0.08 -0.14 -0.44 -0.59 -0.24 -0.03 -0.22 0.11 -0.05 0.17 -0.16 0.39 0.19 -0.02
5741 || orf19.1659 || ALG8 || || Putative glucosyltransferase involved in cell wall mannan biosynthesis; transcription is elevated in nik1 and sln1 homozygous null mutants, but not in the chk1 null mutant; possibly an essential gene, disruptants not obtained by UAU1 method || 1 -0.32 -0.21 -0.17 -0.02 -0.15 -0.62 -0.24 0.01 -0.06 0.23 -0.06 0.23 -0.26 0.13 -0.15 0.02
5742 || orf19.1119 || MTR10 || || Putative importin; member of a family of fungal-specific nuclear importins; Mig1-regulated || 1 -0.82 -0.52 -0.32 -0.17 -0.71 -0.52 -0.30 -0.52 -0.12 0.13 -0.26 0.48 -0.41 0.36 -0.28 -0.07
5743 || orf19.7556 || || || Ortholog of C. dubliniensis CD36 : Cd36_34965, C. parapsilosis CDC317 : CPAR2_200910, Candida tenuis NRRL Y-1498 : CANTEDRAFT_95984 and Debaryomyces hansenii CBS767 : DEHA2E02926g || 1 -0.36 -0.52 -0.21 -0.10 -0.43 -0.59 -0.42 -0.19 -0.01 0.12 -0.37 0.07 -0.12 0.13 -0.08 -0.09
5744 || orf19.5410 || || || Ortholog(s) have microtubule plus-end binding activity and role in conidium formation, nuclear migration along microtubule, regulation of microtubule motor activity, sexual sporulation resulting in formation of a cellular spore || 1 -0.33 -0.43 -0.20 0.19 -0.51 -0.52 -0.37 -0.20 0.03 0.37 -0.23 0.34 0.10 0.25 -0.26 -0.20
5745 || orf19.3467 || SEC27 || || Ortholog(s) have ubiquitin binding activity || 1 -0.54 -0.22 -0.06 0.25 -0.54 -0.44 -0.88 -0.77 0.28 0.13 -0.45 0.73 -0.09 0.30 -0.31 0.09
5746 || orf19.1268 || || || Protein of unknown function; transcript detected on high-resolution tiling arrays; rat catheter biofilm induced || 1 -1.14 -0.65 -0.62 -0.33 -0.96 -0.29 -0.71 -0.33 -0.05 0.40 -0.31 1.73 -0.44 -0.01 -0.64 -0.29
5747 || orf19.978 || BDF1 || || Bromodomain transcription factor; repressed upon adherence to polystyrene; reduced mRNA abundance detected in null mutant; macrophage/pseudohyphal-repressed; possibly essential, disruptants not obtained by UAU1 method || 1 -0.11 -0.08 -0.48 -0.25 -0.90 -0.35 -0.61 -0.37 -0.07 -0.11 -0.06 0.28 0.10 0.39 -0.19 -0.34
5748 || orf19.7232 || IRR1 || || Putative cohesin complex subunit; cell-cycle regulated periodic mRNA expression || 1 -0.52 -0.32 -0.07 0.36 -0.33 -0.67 -0.63 -0.09 -0.31 -0.21 -0.18 -0.09 -0.12 0.27 -0.40 -0.41
5749 || orf19.3323 || || || Ortholog of C. dubliniensis CD36 : Cd36_01240, C. parapsilosis CDC317 : CPAR2_109140, Candida tenuis NRRL Y-1498 : CANTEDRAFT_114227 and Debaryomyces hansenii CBS767 : DEHA2D15026g || 1 -0.40 -0.62 0.50 0.23 -0.56 -0.33 -0.55 -0.23 -0.14 0.12 -0.38 0.04 -0.55 0.03 0.05 0.00
5750 || orf19.2468 || || || Ortholog(s) have trans-aconitate 3-methyltransferase activity and cytosol, nucleus localization || 1 -0.17 -0.45 0.71 0.09 -0.14 -0.06 -0.48 -0.03 -0.06 0.24 -0.52 0.51 -0.57 0.29 0.07 -0.28
5751 || orf19.5172 || LIP9 || || Secreted lipase, member of a lipase gene family whose members are expressed differentially in response to carbon source and during infection; may have a role in nutrition and/or in creating an acidic microenvironment || 1 -0.15 -0.46 0.25 -0.10 -0.03 -0.57 -0.13 0.07 -0.07 -0.75 0.86 -0.63 0.05 -0.77 0.43
5752 || orf19.7511 || || || Ortholog(s) have structural constituent of nuclear pore activity and role in cell division, nuclear pore organization, regulation of mitotic cell cycle || 1 -0.28 -0.26 0.21 0.02 -0.12 -0.04 -0.43 -0.08 0.14 0.38 -0.09 0.25 -0.41 -0.02 -0.56 0.24
5753 || orf19.1084 || CDC39 || || Protein similar to S. cerevisiae Cdc39p, which is part of the CCR4-NOT transcription regulatory complex; transposon mutation affects filamentous growth || 1 -0.06 -0.15 -0.15 0.12 -0.07 -0.08 -0.60 -0.02 0.19 0.11 0.18 0.12 -0.60 0.40 -0.17 0.24
5754 || orf19.2697 || || || Ortholog(s) have role in protein monoubiquitination, regulation of dipeptide transmembrane transport by regulation of transcription from RNA polymerase II promoter and cytoplasm, nucleus localization || 1 -0.52 -0.58 -0.08 0.19 0.02 -0.12 -0.57 0.15 0.02 0.42 -0.01 0.07 -0.56 0.24 -0.11 0.26
5755 || orf19.6802 || || || Ortholog(s) have palmitoyltransferase activity, role in protein palmitoylation, vacuole fusion, non-autophagic and Golgi apparatus, endoplasmic reticulum, fungal-type vacuole membrane localization || 1 -0.52 -0.28 0.13 0.52 -0.25 -0.31 -0.41 -0.09 0.25 -0.03 -0.18 0.05 -0.77 -0.06 -0.09 0.26
5756 || orf19.2943.5 || || || Ortholog of Candida albicans WO-1 : CAWG_05543 || 1 -0.65 -0.54 0.37 1.13 0.08 -0.58 -0.16 -0.06 0.00 -0.02 -0.15 -1.15 0.88 -0.68 0.57
5757 || orf19.609 || || || Protein of unknown function; white cell specific transcript || 1 -0.82 -0.40 -0.04 0.17 -0.29 0.01 0.18 -0.17 0.08 -0.35 0.11 -0.72 0.73 -0.36
5758 || orf19.4521 || || || S. cerevisiae ortholog Env9 has similarity to oxidoreductases and is proposed to have vacuolar functions, found in lipid particles; hyphal-induced expression || 1 -0.26 -0.26 -0.01 0.31 -0.42 -0.30 -0.06 -0.12 0.41 -0.37 -0.06 0.24 0.39 0.33 -0.28 -0.03
5759 || orf19.4633 || || || Ortholog(s) have carbonyl reductase (NADPH) activity, oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor activity and cytosol, nucleus, ribosome localization || 1 -0.09 0.10 0.17 0.22 -0.20 -0.43 -0.14 -0.30 0.36 -0.07 -0.11 0.13 0.15 -0.22 -0.62 -0.08
5760 || orf19.6224 || || || RTA domain protein; predicted role in response to stress; Spider biofilm induced || 1 -0.64 0.01 0.61 0.98 -0.83 -1.77 0.19 -0.63 0.89 0.51 -0.64 -0.44 1.86 0.13 -0.74 -0.41
5761 || orf19.6224 || || || RTA domain protein; predicted role in response to stress; Spider biofilm induced || 1 -1.09 -0.97 -0.19 1.09 -1.77 -2.55 -0.85 -1.51 0.80 -1.27 -2.27 -1.05 1.58 -0.07 -1.35 0.80
5762 || orf19.6224 || || || RTA domain protein; predicted role in response to stress; Spider biofilm induced || 1 -0.75 -0.82 1.27 1.38 -1.07 -3.58 -0.71 -0.49 -0.06 -0.65 -1.17 -0.71 1.53 -0.43 0.23
5763 || orf19.1637 || || || Ortholog(s) have cytosol, nucleus localization || 1 -0.10 -0.12 0.09 0.19 -0.13 -0.61 -0.28 -0.14 -0.05 -0.20 -0.10 -0.10 -0.03 -0.18 -0.06 -0.01
5764 || orf19.4732 || SEC24 || || Protein with a possible role in ER to Golgi transport; induced upon yeast-hyphal switch; sumoylation target; Spider biofilm repressed || 1 -0.29 -0.19 0.22 0.32 -0.30 -0.56 -0.68 -0.49 -0.10 -0.28 -0.37 -0.11 0.00 0.02 -0.26 0.19
5765 || orf19.4496 || || || Ortholog(s) have role in cellular calcium ion homeostasis and Golgi medial cisterna, cis-Golgi network, endoplasmic reticulum, fungal-type vacuole membrane localization || 1 -0.17 0.04 0.04 -0.07 -0.42 -0.72 -0.42 -0.45 -0.01 -0.02 -0.19 0.16 0.30 -0.09 -0.14 0.11
5766 || orf19.3323 || || || Ortholog of C. dubliniensis CD36 : Cd36_01240, C. parapsilosis CDC317 : CPAR2_109140, Candida tenuis NRRL Y-1498 : CANTEDRAFT_114227 and Debaryomyces hansenii CBS767 : DEHA2D15026g || 1 -0.42 -0.56 0.35 0.14 -0.27 -0.45 -0.43 -0.37 0.10 -0.01 -0.33 0.15 0.29 0.03 0.01 -0.24
5767 || orf19.5451 || || || Ortholog of Candida guilliermondii ATCC 6260 : PGUG_05321, Candida lusitaniae ATCC 42720 : CLUG_00887 and Candida albicans WO-1 : CAWG_02354 || 1 -0.07 -0.06 0.31 0.47 -0.19 0.10 -0.48 -0.35 0.13 -1.46 -0.42 0.12 0.47 0.03 0.03 0.13
5768 || orf19.1365 || || || Putative monooxygenase; mutation confers hypersensitivity to toxic ergosterol analog; constitutive expression independent of MTL or white-opaque status || 1 0.33 0.15 0.56 0.70 -0.25 0.24 -0.12 -0.14 0.17 -0.95 -0.33 -0.13 0.18 0.17 -0.14 0.38
5769 || orf19.2176 || IFM3 || || Protein with a 2-hydroxyacid dehydrogenase catalytic domain; Hap43-repressed; Plc1-regulated; overlaps orf19.2177 || 1 -0.01 -0.17 0.19 0.59 -0.24 0.06 0.24 -0.34 0.15 -0.61 -0.37 -0.37 0.09 0.03 -0.00 0.05
5770 || orf19.3132 || || || Predicted endoplasmic reticulum zinc transporter; induced by nitric oxide || 1 -0.33 -0.12 0.57 0.63 -0.50 0.00 -0.53 -0.58 0.00 0.20 -0.56 -0.23 0.60 0.44 -0.05 0.25
5771 || orf19.1365 || || || Putative monooxygenase; mutation confers hypersensitivity to toxic ergosterol analog; constitutive expression independent of MTL or white-opaque status || 1 -0.34 -0.54 0.44 0.25 -0.55 -0.03 -0.45 -0.79 -0.02 -0.84 -0.53 -0.03 -0.08 0.25 -0.38 0.38
5772 || orf19.3569 || || || Protein of unknown function; S. cerevisiae YLR407W mutants have abnormal budding; constitutive expression independent of MTL or white-opaque status; Spider biofilm induced || 1 -0.33 -0.25 0.67 0.58 -0.40 -0.01 -0.62 -0.46 -0.26 -0.65 -0.42 -0.00 0.08 0.02 0.06 0.40
5773 || orf19.4707 || || || Putative secreted acid sphingomyelin phosphodiesterase; possible Kex2p substrate || 1 -0.44 -0.35 0.66 0.62 -0.66 -0.34 -0.29 -1.01 -0.78 -0.66 -0.54 -0.16 -0.03 0.08 0.04 0.39
5774 || orf19.6950 || || || Putative vacuolar membrane transporter for cationic amino acids; Spider biofilm induced || 1 -0.09 -0.41 0.95 0.96 -1.00 -0.19 -0.49 -0.80 -0.02 -0.35 -0.51 0.17 0.23 0.31 -0.02 0.24
5775 || orf19.4494 || KTR2 || || Mannosyltransferase; transcription elevated in chk1, nik1, and sln1 homozygous null mutants; fungal-specific (no human or murine homolog); possibly an essential gene, disruptants not obtained by UAU1 method || 1 -0.15 -0.16 0.55 0.49 -0.35 -0.14 -0.53 -0.36 -0.34 -0.43 -0.06 0.44 -0.26 0.15 -0.22 0.29
5776 || orf19.5896 || || || Protein of unknown function; induced by alpha pheromone in SpiderM medium || 1 0.08 -0.08 0.24 0.62 -0.51 -0.75 -0.44 -0.20 0.04 -0.37 0.10 0.13 0.00 0.47 -0.34 0.30
5777 || orf19.3551 || DAD2 || || Essential subunit of the Dam1 (DASH) complex, which acts in chromosome segregation by coupling kinetochores to spindle microtubules || 1 -0.24 -0.36 0.82 0.96 -0.72 -0.63 -0.41 -0.14 -0.25 -0.35 -0.02 0.48 0.46 0.59 -0.80 0.34
5778 || orf19.1178 || || || Putative transcription factor with bZIP DNA-binding motif; Hap43p-repressed gene || 1 -0.22 -0.08 0.45 0.33 -0.18 -0.23 -0.35 0.23 0.23 -0.29 -0.01 0.24 0.04 0.24 -0.26 0.56
5779 || orf19.7579 || FGR34 || || Protein lacking an ortholog in S. cerevisiae; transposon mutation affects filamentous growth || 1 -0.08 -0.22 0.45 0.47 -0.18 -0.25 -0.34 -0.28 0.20 -0.35 -0.69 0.12 -0.20 -0.29 -0.41 0.26
5780 || orf19.6851 || CHL4 || || Protein described as having role in chromosome segregation; RNA abundance regulated by tyrosol and cell density || 1 -0.45 -0.19 0.60 0.37 -0.00 -0.19 -0.41 -0.28 0.24 -0.03 -0.13 -0.04 0.17 0.28 -0.39 -0.14
5781 || orf19.6863 || VPH1 || || Vacuolar H(+)-ATPase; transcription regulated by Nrg1, Mig1, and Tup1 || 1 -0.19 0.01 0.43 0.18 0.08 -0.30 -0.29 -0.35 0.31 -0.02 -0.22 -0.08 0.33 -0.25 -0.39 0.04
5782 || orf19.1208 || || || Predicted ORF in the Major Repeat Sequence on chromosome 4; member of a family encoded by FGR6-related genes in the RB2 repeat sequence || 1 -0.02 0.01 0.53 0.32 0.15 -0.38 -0.56 -0.25 0.27 -0.16 -0.24 -0.27 0.18 -0.06 -0.10 0.14
5783 || orf19.5971 || || || Ortholog of S. cerevisiae : MTC6, C. glabrata CBS138 : CAGL0I01892g, C. dubliniensis CD36 : Cd36_84990, C. parapsilosis CDC317 : CPAR2_405620 and Candida tenuis NRRL Y-1498 : CANTEDRAFT_99433 || 1 -0.06 0.04 0.63 0.48 0.23 -0.18 -0.31 -0.36 0.20 -0.40 -0.32 -0.10 0.10 0.01 -0.13 0.22
5784 || orf19.5443 || BNA4 || || Putative kynurenine 3-monooxygenase, involved in NAD biosynthesis; transposon mutation affects filamentous growth; Hap43p-repressed gene; oral infection upregulated; mutants have reduced capacity to damage oral epithelial cells || 1 -0.22 0.04 1.20 0.45 -0.19 0.03 -0.85 -0.75 0.22 -0.37 -0.68 -0.09 0.04 -0.36 -0.16 0.56
5785 || orf19.1234 || FGR6-10 || || Protein lacking an ortholog in S. cerevisiae; member of a family encoded by FGR6-related genes in the RB2 repeat sequence; transposon mutation affects filamentous growth || 1 -0.28 -0.08 1.16 0.64 -0.14 0.05 -1.16 -0.76 0.59 -0.14 -0.21 -0.46 0.04 -0.39 -0.37 0.29
5786 || orf19.782 || || || Ortholog(s) have serine hydrolase activity, triglyceride lipase activity, role in lipid homeostasis and lipid particle localization || 1 -0.21 -0.10 0.58 0.46 -0.08 -0.16 -0.92 -0.70 0.55 -0.00 -0.29 -0.42 0.33 0.21 -0.23 0.14
5787 || orf19.2663 || || || Ortholog of Pichia stipitis Pignal : PICST_29216 and Candida albicans WO-1 : CAWG_00788 || 1 0.17 -0.08 0.51 0.60 -0.11 -0.25 -0.55 -0.39 0.16 0.01 -0.19 -0.27 -0.02 0.23 -0.52 0.31
5788 || orf19.834 || || || Ortholog(s) have carbohydrate binding, mannosyl-oligosaccharide 1,2-alpha-mannosidase activity, role in ER-associated ubiquitin-dependent protein catabolic process and endoplasmic reticulum lumen localization || 1 0.07 0.11 0.35 0.47 0.05 -0.27 -0.39 -0.48 0.17 -0.14 -0.43 0.29 0.07 0.04 -0.34 0.15
5789 || orf19.876 || PGA33 || || Putative GPI-anchored protein of unknown function; Spider biofilm repressed || 1 0.04 0.09 0.19 0.21 0.15 -0.19 -0.31 -0.26 0.09 -0.28 -0.30 0.17 0.14 0.30 -0.10 -0.03
5790 || orf19.834 || || || Ortholog(s) have carbohydrate binding, mannosyl-oligosaccharide 1,2-alpha-mannosidase activity, role in ER-associated ubiquitin-dependent protein catabolic process and endoplasmic reticulum lumen localization || 1 -0.03 -0.11 0.43 0.33 0.01 -0.32 -0.12 -0.31 0.54 -0.21 -0.33 -0.03 0.17 0.27 0.03 0.02
5791 || orf19.2585 || || || Ortholog of Candida albicans WO-1 : CAWG_01548 || 1 0.06 -0.08 0.87 0.17 0.05 -0.74 0.14 -0.70 0.31 -0.35 0.10 -0.05 -0.31 -0.71 -0.20
5792 || orf19.1824 || PGA50 || || Putative GPI-anchored protein; adhesin-like protein || 1 0.30 -0.13 1.38 0.57 -0.14 -0.39 -0.44 -0.01 -0.13 -0.60 -0.50 -0.65 -0.11 0.39 -0.52 -0.55
5793 || orf19.6867 || || || Protein with a predicted cytochrome b5-like heme/steroid binding domain; repressed by alpha pheromone in SpiderM medium || 1 0.36 0.35 0.90 0.64 -0.38 -0.31 -0.00 -0.19 0.33 -0.28 -0.47 0.20 -0.03 0.04 -0.63 -0.00
5794 || orf19.6867 || || || Protein with a predicted cytochrome b5-like heme/steroid binding domain; repressed by alpha pheromone in SpiderM medium || 1 0.39 0.30 0.89 0.35 -0.23 -0.37 0.09 -0.18 -0.04 -0.57 -0.19 0.08 0.01 -0.02 -0.37 0.10
5795 || orf19.486 || NIP100 || || p150 subunit of dynactin; required for normal spindle formation and position || 1 0.03 -0.07 0.44 0.44 0.02 -0.26 -0.08 -0.23 0.30 -0.40 0.05 -0.11 0.14 0.06 -0.25 0.10
5796 || orf19.4702 || || || Possible similarity to mutator-like element (MULE) transposase; flow model biofilm induced; expression regulated during planktonic growth || 1 -0.01 -0.02 0.50 0.27 -0.19 -0.30 -0.18 -0.01 0.16 -0.27 0.02 -0.07 0.10 -0.04 -0.42 -0.08
5797 || orf19.2227 || || || Protein of unknown function; flow model biofilm induced; nitric oxide-repressed || 1 0.17 -0.15 0.97 0.75 0.27 -0.71 -0.22 -0.01 0.01 -0.36 -0.20 0.14 -0.14 0.21 -0.64 0.01
5798 || orf19.3289 || || || Phosphorylated protein of unknown function || 1 -0.05 -0.19 0.54 0.68 0.10 -0.48 -0.00 0.26 0.20 -0.31 0.05 -0.02 0.19 0.05 -0.35 -0.39
5799 || orf19.1843 || ALG6 || || Putative glucosyltransferase involved in cell wall mannan biosynthesis; transcription is elevated in chk1, nik1, and sln1 homozygous null mutants; repressed by nitric oxide; possibly essential gene, disruptants not obtained by UAU1 method || 1 0.09 0.19 0.61 0.57 -0.04 -0.37 -0.02 0.17 0.24 -0.09 -0.01 -0.34 0.09 -0.38 -0.36 -0.09
5800 || orf19.7329 || || || Ortholog(s) have ubiquitin-protein ligase activity || 1 0.45 0.20 0.44 0.54 0.06 -0.46 -0.33 -0.03 0.58 -0.25 -0.35 -0.32 0.46 -0.07 -0.23 0.14
5801 || orf19.7321 || || || Ortholog(s) have role in re-entry into mitotic cell cycle after pheromone arrest and endoplasmic reticulum localization || 1 -0.09 0.02 0.45 0.28 -0.34 -0.22 -0.20 0.05 0.06 -0.17 -0.26 -0.04 -0.24 -0.28 0.07 0.27
5802 || orf19.6324 || VID27 || || Protein similar to S. cerevisiae Vid27p; transposon mutation affects filamentous growth; mutation confers hypersensitivity to toxic ergosterol analog; fungal-specific (no human or murine homolog) || 1 0.08 -0.03 0.77 0.56 -0.29 -0.07 -0.34 -0.14 0.00 -0.24 -0.05 -0.05 -0.41 -0.28 0.24 0.32
5803 || orf19.2517 || || || Predicted membrane transporter, member of the drug:proton antiporter (12 spanner) (DHA1) family, major facilitator superfamily (MFS) || 1 -0.09 -0.06 1.13 0.73 -0.22 -0.10 -0.08 -0.50 -0.18 -0.36 -0.45 -0.10 -0.45 -0.39 -0.20 0.37
5804 || orf19.2312 || || || Protein similar to ferric reductase Fre10p; possibly an essential gene, disruptants not obtained by UAU1 method || 1 -0.04 -0.45 1.40 0.53 -0.47 0.16 -0.13 -0.02 -0.08 -0.19 -0.40 -0.22 -0.31 -0.59 -0.01 0.88
5805 || orf19.4116 || || || Ortholog(s) have N-acetyltransferase activity, role in response to drug and nuclear envelope, plasma membrane localization || 1 0.23 -0.51 0.71 0.47 -1.05 0.05 -0.17 -0.40 0.44 -0.27 -0.19 -0.12 -0.37 0.15 0.38 0.08
5806 || orf19.2281 || || || Ortholog(s) have mitochondrion localization || 1 -0.38 0.15 0.38 0.69 -0.92 -0.06 0.08 0.02 0.32 -0.45 -0.66 -0.10 0.04 0.15 0.32 0.21
5807 || orf19.4682 || HGT17 || || Putative MFS family glucose transporter; 20 members in C. albicans; 12 probable membrane-spanning segments; induced at low (0.2%, compared to 2%) glucose in rich media; Spider biofilm induced || 1 -0.19 -0.69 0.93 0.33 0.59 0.17 0.11 -0.04 -0.39 0.02 -1.08 -0.27 -0.44 -0.65 0.35 -0.31
5808 || orf19.5454 || DAL1 || || Putative allantoinase; transcript regulated by Nrg1 and Mig1; macrophage/pseudohyphal-repressed || 1 -0.01 -0.15 0.83 0.34 0.18 0.73 0.01 0.01 0.08 0.44 -0.75 -0.40 -0.03 0.38 -0.10 0.02
5809 || orf19.1548 || || || Ortholog(s) have role in mRNA splicing, via spliceosome and U4/U6 x U5 tri-snRNP complex localization || 1 0.08 -0.16 0.72 0.75 -0.02 0.34 -0.03 -0.11 0.08 0.19 -0.84 -0.32 -0.17 0.01 -0.37 0.10
5810 || orf19.7460 || || || Putative 2'-O-methyltransferase with a predicted role in tRNA modification; transcription is activated in the presence of elevated CO2 || 1 -0.27 -0.13 0.91 0.62 -0.05 0.24 -0.20 -0.24 0.17 -0.04 -0.49 -0.02 0.22 0.11 -0.09 0.17
5811 || orf19.2808 || ZCF16 || || Predicted Zn(II)2Cys6 transcription factor; mutants are viable; rat catheter biofilm induced || 1 0.04 -0.05 0.54 0.93 0.18 0.31 0.07 0.08 0.19 0.08 -0.84 0.10 -0.01 0.20 0.25 -0.20
5812 || orf19.5105 || MED15 || || RNA polymerase II mediator complex subunit; possibly an essential gene, disruptants not obtained by UAU1 method || 1 -0.05 -0.27 0.27 0.48 -0.12 0.02 -0.11 0.15 0.07 -0.05 -0.39 -0.11 -0.05 0.00 -0.12 0.03
5813 || orf19.6464 || || || Protein of unknown function; induced upon adherence to polystyrene; oxidative stress-induced via Cap1 || 1 0.13 0.28 0.32 0.35 0.13 0.19 -0.06 -0.13 0.05 -0.09 -0.07 0.27 -0.65 0.31 -0.02 0.33
5814 || orf19.2624 || || || Protein of unknown function; downregulated by fluphenazine treatment or in an azole-resistant strain that overexpresses CDR1 and CDR2 || 1 0.39 0.23 0.48 0.01 0.19 -0.55 -0.02 -0.09 0.07 0.68 -0.80 -0.47 0.79
5815 || orf19.5129 || || || Ortholog of C. dubliniensis CD36 : Cd36_72910, C. parapsilosis CDC317 : CPAR2_704100, Candida tenuis NRRL Y-1498 : CANTEDRAFT_113193 and Debaryomyces hansenii CBS767 : DEHA2E23100g || 1 0.26 0.20 0.73 0.74 -0.03 0.13 -0.54 -0.14 0.35 -0.24 0.32 0.48 -0.55 -0.27 -0.02 0.24
5816 || orf19.2568 || IFU5 || || Predicted membrane protein; estradiol-induced; upregulation associated with CDR1 and CDR2 overexpression or fluphenazine; putative drug-responsive regulatory site; similar to S. cerevisiae Wwm1p; Hap43-repressed; Spider biofilm repressed || 1 -0.01 -0.00 0.59 0.87 0.01 0.16 -0.33 -0.42 0.34 -0.23 -0.17 0.54 -0.06 0.48 0.19 0.17
5817 || orf19.1336 || PUP3 || || Putative beta 3 subunit of the 20S proteasome; macrophage/pseudohyphal-repressed || 1 0.14 0.23 0.65 0.79 0.01 0.29 -0.74 -0.57 0.24 -0.03 0.23 0.51 -0.12 0.16 0.08 0.39
5818 || orf19.2867 || || || Ortholog(s) have phosphatidylinositol-3-phosphate binding, protein transporter activity and role in ascospore formation, intracellular protein transport, protein retention in Golgi apparatus, retrograde transport, endosome to Golgi || 1 0.07 0.10 0.57 0.57 0.34 0.27 -0.33 -0.19 -0.05 0.01 0.22 0.34 -0.11 0.25 0.50 0.49
5819 || orf19.7208 || CSK1 || || Putative mitogen-activated protein (MAP) kinase with an unknown role; null mutant produces wrinkled colonies; similar to S. cerevisiae Smk1p, which is a protein kinase required for sporulation || 1 0.14 0.35 0.41 0.84 0.48 0.12 -0.15 0.28 -0.28 0.29 0.08 -0.19 0.29 0.49
5820 || orf19.7503 || CDA2 || || Putative chitin deacetylase; transcription is positively regulated by Tbf1p || 1 0.12 0.11 0.66 0.60 0.46 -0.03 0.07 0.12 -0.08 -0.07 -0.32 0.37 -0.23 0.28 0.23 0.01
5821 || orf19.7002 || || || Ortholog of C. parapsilosis CDC317 : CPAR2_806990, Candida tenuis NRRL Y-1498 : CANTEDRAFT_122709, Debaryomyces hansenii CBS767 : DEHA2E00110g and Pichia stipitis Pignal : PICST_30109 || 1 -0.25 -0.20 0.63 1.31 0.87 -0.10 0.18 0.02 -0.15 0.01 -0.06 0.31 -0.59 0.01 -0.11 0.44
5822 || orf19.5231 || || || Protein of unknown function; flow model biofilm induced || 1 -0.33 0.58 0.46 1.22 -0.12 0.08 0.19 -0.02 -0.21 -0.14 -0.14 0.57 -0.36 0.56 -0.13 0.10
5823 || orf19.4627 || || || Ortholog(s) have structural constituent of nuclear pore activity || 1 -0.05 0.00 0.11 0.56 0.10 0.09 -0.36 -0.25 0.03 -0.26 -0.16 0.16 -0.05 -0.24 -0.04 -0.07
5824 || orf19.203 || STB3 || || Putative SIN3-binding protein 3 homolog; caspofungin induced; macrophage/pseudohyphal-repressed; rat catheter biofilm induced || 1 -0.32 -0.05 0.71 1.16 0.23 -0.40 -0.54 -0.74 -0.23 -0.26 -0.06 0.24 0.29 -0.54 0.32 0.31
5825 || orf19.5025 || MET3 || || ATP sulfurlyase; sulfate assimilation; repressed by Met, Cys, Sfu1, or in fluconazole-resistant isolate; Hog1, caspofungin, white phase-induced; induced on biofilm formation, even in presence of Met and Cys; Spider, F-12/CO2 biofilm induced || 1 -0.35 -0.16 1.20 1.79 -0.43 -0.51 -0.50 -0.50 -0.21 -0.22 0.10 0.22 -0.56 -0.90 0.09 0.09
5826 || orf19.2537 || || || Protein of unknown function; transcript detected on high-resolution tiling arrays || 1 0.23 0.33 0.23 0.78 0.15 -0.30 -0.04 0.28 -0.30 -0.57 0.07 0.15 -0.46 -0.64 0.14 0.10
5827 || orf19.6520 || || || Putative allantoate permease; fungal-specific (no human or murine homolog) || 1 1.03 0.20 0.28 2.13 -0.11 -1.07 -0.15 0.03 -1.42 -0.46 -0.28 0.72 -1.23 0.25 0.02
5828 || orf19.272 || FAA21 || || Predicted acyl CoA synthetase; upregulated upon phagocytosis; transcript regulated by Nrg1 and Mig1 || 1 0.36 0.22 0.16 0.82 -0.28 -0.04 -0.04 -0.04 -0.26 -0.27 0.04 0.34 -0.64 -0.45 -0.03 0.24
5829 || orf19.2583 || PTR2 || || Oligopeptide transporter involved in uptake of di-/tripeptides; highly induced during chlamydospore formation in both C. albicans and C. dubliniensis || 1 0.11 -0.17 0.92 1.14 -0.49 -0.29 -0.53 -0.02 0.07 -0.37 0.12 0.17 -0.70 0.13 -0.32 -0.01
5830 || orf19.6115 || || || Dubious open reading frame || 1 0.54 -0.28 0.55 1.98 -0.47 -0.41 -1.05 0.73 -0.64 -0.50 -0.16 0.74 -0.67 -0.33 -1.08
5831 || orf19.6142 || || || Ortholog(s) have double-stranded DNA binding activity, role in reciprocal meiotic recombination and condensed nuclear chromosome localization || 1 -0.04 -0.48 0.63 2.81 -0.22 -0.05 0.30 0.60 -0.96 0.22 -0.17 0.38 0.09 -0.00 0.22 -0.47
5832 || orf19.5216 || || || Has domain(s) with predicted acyl-CoA hydrolase activity and role in acyl-CoA metabolic process || 1 0.45 0.27 0.94 1.69 -0.51 -0.42 -0.06 0.06 -0.34 -0.20 0.04 0.13 0.05 -0.27 0.20 -0.05
5833 || orf19.2313 || || || Putative ortholog of S. cerevisiae Pex32 a peroxisomal integral membrane protein with a role in negative regulation of peroxisome size; Hap43-repressed gene || 1 0.14 0.20 0.42 0.88 0.12 -0.54 0.05 0.03 -0.12 0.06 -0.09 0.10 0.13 -0.06 0.12 -0.17
5834 || orf19.6060 || GCN20 || || YEF3-subfamily ABC family protein, predicted not to be a transporter || 1 0.26 0.04 0.40 0.48 0.25 -0.14 -0.15 0.13 -0.08 0.06 0.11 -0.25 0.14 -0.39 -0.14 0.12
5835 || orf19.2496 || ATO2 || || Putative fungal-specific transmembrane protein; fluconazole repressed, Hap43-repressed; flow model biofilm induced; Spider biofilm induced || 1 0.10 0.06 0.51 1.04 0.10 -0.39 -0.20 0.20 -0.67 0.36 -0.04 -0.45 -0.07 -0.62 0.14 0.44
5836 || orf19.10712 || MTLALPHA1 || || Master regulator (activator) of alpha mating type; gene of the MTLalpha (Mating Type Like) locus; ortholog of S. cerevisiae Alpha1p; a/alpha mating type may increase virulence, offers competitive advantage || 1 0.54 0.22 0.92 0.24 -0.50 -0.58 -0.06 -0.51 0.50 -0.21 -0.25 -0.58 -1.02 -0.11 0.22
5837 || orf19.3183 || || || Protein with a role in insertion of tail-anchored proteins into the ER membrane; required for efficient mating, in shmoo formation and nuclear migration in the pre-zygote of S. cerevisiae; Hap43-repressed || 1 0.27 0.23 0.65 0.97 -0.25 -0.55 -0.37 0.30 -0.05 0.51 0.07 0.08 -0.28 -0.62 0.17 -0.02
5838 || orf19.6838 || || || Putative protein of unknown function, transcript upregulated in clinical isolates from HIV+ patients with oral candidiasis; Spider biofilm induced || 1 0.25 0.21 1.20 1.59 -0.21 -0.47 -0.31 0.50 -0.42 0.44 -0.59 0.15 -0.70 -0.89 0.32 -0.97
5839 || orf19.1494 || RAD23 || || S. cerevisiae Rad23 ortholog; binds damaged DNA; Spider biofilm repressed || 1 0.11 0.05 0.55 0.55 0.11 -0.02 -0.26 0.27 -0.31 0.47 -0.17 0.00 -0.30 -0.14 -0.01 -0.22
5840 || orf19.5418 || || || Ortholog(s) have role in ER to Golgi vesicle-mediated transport and endoplasmic reticulum localization || 1 0.04 0.32 0.35 0.34 0.15 -0.39 0.05 0.38 0.12 0.32 -0.03 -0.05 -0.28 -0.55 -0.11 -0.05
5841 || orf19.4102 || RPN10 || || Putative 19S regulatory particle of the 26S proteasome; macrophage/pseudohyphal-repressed; regulated by Gcn2 and Gcn4; Spider biofilm repressed || 1 0.27 0.18 0.44 0.36 -0.12 -0.15 -0.22 -0.18 -0.24 0.06 -0.05 -0.30 -0.31 -0.49 0.59 -0.08
5842 || orf19.6999 || || || Predicted oxidoreductase; rat catheter biofilm repressed || 1 0.25 0.50 0.98 1.59 0.25 0.63 -0.50 -0.60 0.26 0.09 -0.84 -0.21 -1.11 -0.42 1.69 0.19
5843 || orf19.5963 || || || Putative prenyltransferase; essential gene in S. cerevisiae; Spider biofilm induced || 1 0.29 0.05 0.93 1.21 0.24 0.30 -0.26 -0.22 -0.21 0.25 -0.23 -0.15 -0.13 0.19 0.72 0.02
5844 || orf19.5751 || ORM1 || || Putative endoplasmic reticulum membrane protein; Hap43p-repressed gene; mutation confers hypersensitivity to aureobasidin A || 1 0.20 0.23 0.46 0.35 0.15 0.21 -0.20 -0.16 -0.16 0.12 -0.17 -0.21 -0.16 0.26 0.65 0.09
5845 || orf19.5616 || || || Ortholog of C. dubliniensis CD36 : Cd36_63740, C. parapsilosis CDC317 : CPAR2_503850, Pichia stipitis Pignal : PICST_32045 and Candida guilliermondii ATCC 6260 : PGUG_00070 || 1 0.79 0.54 1.14 0.65 0.26 0.33 -0.11 0.56 -0.71 -0.18 -0.27 -0.22 -0.61 -0.34 0.41 0.23
5846 || orf19.707 || APG7 || || Ortholog(s) have APG12 activating enzyme activity, APG8 activating enzyme activity || 1 0.59 0.09 0.95 0.94 -0.08 -0.12 -0.10 0.12 -0.38 -0.06 -0.80 -0.30 -0.55 -0.20 0.26 0.23
5847 || orf19.4548 || MAK32 || || Putative protein involved in the structural stability of L-A double-stranded RNA-containing particles; downregulated upon adherence to polystyrene || 1 0.54 -0.07 0.83 0.87 0.03 0.21 0.01 0.31 -0.04 -0.01 -0.35 -0.12 -0.19 0.09 -0.01 0.23
5848 || orf19.2711.1 || MED20 || || Subunit of the RNA polymerase II mediator complex; involved in control of filamentous growth and Spider biofilm formation; rat catheter biofilm repressed || 1 0.35 0.33 0.32 0.46 -0.18 -0.15 -0.37 0.17 0.14 0.19 0.01 -0.03 -0.18 0.22 0.17 0.16
5849 || orf19.7456 || || || Protein of unknown function; flow model biofilm repressed || 1 0.45 0.69 1.02 0.83 -0.45 -0.24 -0.33 -0.13 0.06 0.36 -0.37 -0.21 -0.05 0.07 0.46 0.57
5850 || orf19.479.2 || SEC22 || || Ortholog(s) have SNAP receptor activity and role in ER to Golgi vesicle-mediated transport, retrograde vesicle-mediated transport, Golgi to ER, vesicle fusion with Golgi apparatus || 1 0.10 0.12 0.76 0.96 -0.22 -0.08 -0.32 -0.50 -0.08 0.25 -0.46 0.00 -0.11 0.00 0.07 0.22
5851 || orf19.5963 || || || Putative prenyltransferase; essential gene in S. cerevisiae; Spider biofilm induced || 1 -0.17 -0.21 0.56 0.87 -0.11 -0.13 -0.78 -0.49 0.07 0.47 -0.59 -0.31 -0.23 0.33 0.15 -0.23
5852 || orf19.5215 || TES15 || || Putative acyl-CoA thioesterase; Hap43-repressed; Spider biofilm induced || 1 0.13 0.01 0.56 0.67 -0.25 -0.33 -0.44 -0.15 0.41 0.37 -0.96 -0.39 -0.26 0.26 0.21 -0.11
5853 || orf19.850 || || || Ortholog(s) have protein-N-terminal asparagine amidohydrolase activity, protein-N-terminal glutamine amidohydrolase activity and role in cellular protein modification process, protein catabolic process || 1 0.56 0.04 0.61 0.53 -0.88 -0.45 -0.52 0.17 0.52 0.75 -0.71 -0.12 -0.69 0.58 0.09 0.09
5854 || orf19.2233 || PRE2 || || Putative proteasome beta-5 subunit; macrophage-induced protein || 1 0.42 0.18 0.44 0.74 -0.38 -0.42 -0.40 -0.04 -0.09 0.35 -0.56 0.04 -0.43 -0.03 0.04 0.15
5855 || orf19.7411 || OAC1 || || Putative mitochondrial inner membrane transporter; rat catheter biofilm induced || 1 0.49 0.62 0.75 1.04 -0.35 -0.05 0.12 -0.35 0.31 0.93 -0.47 0.07 0.11 -0.12 -0.08 0.20
5856 || orf19.6583 || || || Protein of unknown function; induced by alpha pheromone in SpiderM medium || 1 0.29 0.30 0.68 0.77 -0.15 0.05 -0.31 -0.14 0.11 0.52 -0.34 0.57 0.21 0.76 -0.18 -0.15
5857 || orf19.6205 || || || Ortholog of C. dubliniensis CD36 : Cd36_06550, C. parapsilosis CDC317 : CPAR2_209030, Candida tenuis NRRL Y-1498 : CANTEDRAFT_111035 and Debaryomyces hansenii CBS767 : DEHA2F25300g || 1 0.15 -0.09 0.49 0.78 -0.54 -0.14 -0.30 0.19 0.30 0.47 -0.24 0.25 0.33 0.61 -0.15 -0.09
5858 || orf19.3667 || || || Ortholog(s) have microtubule motor activity, protein homodimerization activity and kinesin complex localization || 1 0.02 0.19 0.64 0.47 -0.23 -0.46 -0.26 -0.14 -0.05 -0.15 -0.17 0.42 0.20 -0.08 0.01 -0.17
5859 || orf19.4415 || MED3 || || RNA polymerase II mediator complex subunit || 1 0.01 0.08 0.51 0.56 -0.10 -0.72 -0.37 -0.25 0.09 -0.04 -0.03 0.26 0.23 -0.06 0.13 0.06
5860 || orf19.7282 || PEX13 || || Protein required for peroxisomal protein import mediated by PTS1 and PTS2 targeting sequences; transcript induced in an RHE model of oral candidiasis; Hap43-repressed gene || 1 0.14 0.24 0.33 0.59 0.05 -0.44 -0.12 -0.31 -0.13 0.08 -0.49 0.17 0.16 -0.17 0.45 -0.07
5861 || orf19.1659 || ALG8 || || Putative glucosyltransferase involved in cell wall mannan biosynthesis; transcription is elevated in nik1 and sln1 homozygous null mutants, but not in the chk1 null mutant; possibly an essential gene, disruptants not obtained by UAU1 method || 1 0.11 0.01 0.34 0.37 0.15 -0.14 -0.30 -0.21 0.17 0.18 -0.15 0.22 0.23 0.08 0.08 0.05
5862 || orf19.4142 || || || Putative transporter; decreased transcription is observed upon fluphenazine treatment || 1 0.25 -0.02 0.38 0.57 -0.28 -0.68 -0.62 0.12 0.25 0.73 -0.22 0.47 -0.21 -0.09 0.22 -0.16
5863 || orf19.609 || || || Protein of unknown function; white cell specific transcript || 1 -0.32 0.45 0.37 0.56 -0.57 -0.90 -0.72 -0.34 0.84 0.58 -0.13 -0.01 -0.01 0.38 -0.34
5864 || orf19.2412 || || || Ortholog(s) have role in late endosome to vacuole transport via multivesicular body sorting pathway and Golgi apparatus, Vps55/Vps68 complex, fungal-type vacuole membrane, late endosome localization || 1 0.15 0.13 0.62 0.67 -0.59 -0.25 -0.55 -0.05 0.17 0.29 0.01 0.04 -0.07 -0.38 0.00 -0.33
5865 || orf19.5722 || || || Ortholog(s) have DNA binding activity || 1 0.53 0.17 0.59 0.53 -0.53 0.06 -0.44 -0.06 0.47 0.34 -0.06 0.28 -0.16 -0.29 -0.73 -0.32
5866 || orf19.5475 || || || Sef1p-, Sfu1p-, and Hap43p-regulated gene || 1 -0.02 -0.08 0.31 0.64 -0.80 0.42 -0.79 -0.26 -0.23 0.54 0.04 0.72 -0.16 -0.90 0.17 0.09
5867 || orf19.2180 || || || Ortholog(s) have calcium ion binding, zinc ion binding activity, role in axial cellular bud site selection, bipolar cellular bud site selection, regulation of COPII vesicle coating and cellular bud neck, cytosol, nucleus localization || 1 0.12 0.00 0.22 0.43 -0.67 -0.07 -0.38 -0.39 -0.11 0.30 -0.28 0.28 -0.28 -0.28 0.40 0.01
5868 || orf19.2447 || || || Putative Type II phosphatidylinositol 4-kinase; Ssr1-repressed; flow model biofilm repressed || 1 0.40 0.30 0.39 0.40 -0.08 0.01 -0.44 -0.33 0.09 0.44 -0.03 0.38 -0.27 -0.56 0.61 0.17
5869 || orf19.2071 || || || Protein of unknown function; induced by alpha pheromone in SpiderM medium || 1 1.09 -0.69 0.42 1.41 -0.39 -0.50 -0.45 -0.69 -0.25 -1.01 -0.22 1.50 0.33 -0.65 0.35 0.55
5870 || orf19.3237 || || || Ortholog(s) have cytosol, mitochondrion, nucleus localization || 1 0.15 0.17 0.34 0.30 -0.17 -0.00 0.01 -0.09 0.68 0.05 -0.37 0.13 -0.08 -0.16 0.23 0.18
5871 || orf19.6973 || || || ATP-dependent LON protease family member; Hap43-repressed gene; regulated by Gcn2 and Gcn4; Spider biofilm induced || 1 0.36 0.42 0.39 0.68 -0.01 -0.32 0.17 -0.05 0.52 -0.42 -0.60 0.28 -0.09 0.18 0.23 0.08
5872 || orf19.3237 || || || Ortholog(s) have cytosol, mitochondrion, nucleus localization || 1 0.25 0.04 0.09 0.09 -0.02 -0.05 0.11 -0.25 0.46 -0.15 -0.77 0.09 -0.43 0.18 0.21 0.36
5873 || orf19.7576 || || || Ortholog of S. pombe atl1 alkyltransferase-like protein; mutants are viable; Spider biofilm induced || 1 0.38 0.27 0.00 0.23 0.25 0.11 0.00 -0.16 -0.11 -0.54 -0.33 -0.61 -0.33 0.15 -0.06 -0.02
5874 || orf19.6200 || || || Pry family pathogenesis-related protein; oral infection upregulated gene; mutant has reduced capacity to damage oral epithelial cells || 1 0.05 0.76 0.62 0.07 -0.81 -1.09 -0.16 -0.41 -0.47 0.15 0.39 -1.78 -0.38 -0.44 -1.28 0.34
5875 || orf19.747 || NBP35 || || Similar to nucleotide-binding proteins; increased transcription is observed upon benomyl treatment; transcription is induced upon filamentous growth || 1 0.06 -0.06 0.24 0.26 -0.57 0.05 0.08 -0.40 -0.24 -0.30 -0.14 -0.25 -0.02 -0.21 -0.31 0.35
5876 || orf19.6833.2 || || || Ortholog of Candida albicans WO-1 : CAWG_00951 || 1 -0.08 0.08 -0.21 0.40 -0.66 -0.18 -0.73 0.03 0.08 -1.08 -0.31 -0.22 -0.67
5877 || orf19.4191.1 || || || Ortholog(s) have ubiquitin-ubiquitin ligase activity, role in ER-associated ubiquitin-dependent protein catabolic process, protein polyubiquitination and cytosol, nuclear envelope, proteasome complex localization || 1 0.10 -0.18 0.04 0.14 -0.15 -0.02 -0.19 -0.22 -0.05 -0.55 -0.29 -0.14 -0.38 0.02 -0.19 0.34
5878 || orf19.1756 || GPD1 || || Glycerol-3-phosphate dehydrogenase; glycerol biosynthesis; regulated by Efg1; regulated by Tsa1, Tsa1B under H2O2 stress conditions; Sflow model and Spider biofilm induced || 1 0.22 0.14 0.07 -0.13 -0.47 -0.62 0.42 -0.46 -0.21 -1.00 -0.36 -0.63 -0.26 0.22 -2.19 1.05
5879 || orf19.5555 || || || Ortholog of C. dubliniensis CD36 : Cd36_63300, Candida tropicalis MYA-3404 : CTRG_05769 and Candida albicans WO-1 : CAWG_05077 || 1 0.34 0.24 -0.21 0.10 -0.26 0.08 -0.38 -0.36 -0.36 -0.46 -0.27 -0.43 -0.09 -0.04 -1.25 -0.10
5880 || orf19.3904 || MRV4 || || Protein of unknown function; Spider biofilm induced || 1 0.74 0.60 0.35 -0.92 -0.64 -0.17 -1.40 -1.12 -0.57 -1.53 -0.58 -0.86 0.17 -2.62
5881 || orf19.7480 || || || Putative protein of unknown function; transcript is upregulated in clinical isolates from HIV+ patients with oral candidiasis || 1 0.24 0.43 -0.24 -0.10 0.15 -0.82 -0.98 -1.29 -0.86 -1.23 -0.32 -1.13 0.34 -0.51 -1.01 0.36
5882 || orf19.3522 || || || Protein of unknown function; flow model biofilm induced; transcript repressed by ciclopirox olamine || 1 0.01 -0.35 -0.22 -0.32 0.15 -0.67 -0.64 -0.33 -0.12 -0.65 -0.36 -0.59 0.36 -0.43 -1.21 0.56
5883 || orf19.7317 || UGA33 || || Zinc-finger transcription factor; similar to S. cerevisiae Uga3 which regulates gamma-aminobutyrate metabolism gene expression; required for yeast cell adherence to silicone substrate; rat catheter biofilm induced || 1 0.36 0.30 0.13 0.03 -0.12 -0.40 -0.49 -0.34 -0.45 -0.24 -0.28 -0.04 0.09 0.09 -0.55 0.56
5884 || orf19.7484 || ADE1 || || Phosphoribosylaminoimadazole succinocarboxamide synthetase, enzyme of adenine biosynthesis; not induced in GCN response, unlike the S. cerevisiae ortholog; fungal-specific (no human or murine homolog); levels decrease in stationary phase || 1 1.14 1.11 0.34 0.50 -0.40 -0.01 -0.01 -0.03 0.07 -0.55 -0.47 -0.08 0.06 0.23 -0.23 -0.32
5885 || orf19.2598 || VMA4 || || H+ transporting ATPase E chain; transcript regulated by Mig1; caspofungin repressed; protein level decreases in stationary phase cultures; rat catheter biofilm repressed || 1 1.08 1.04 0.36 0.48 -0.39 -0.02 -0.35 -0.48 0.07 -0.12 -0.74 0.17 0.70 0.22 -0.55 -0.14
5886 || orf19.7484 || ADE1 || || Phosphoribosylaminoimadazole succinocarboxamide synthetase, enzyme of adenine biosynthesis; not induced in GCN response, unlike the S. cerevisiae ortholog; fungal-specific (no human or murine homolog); levels decrease in stationary phase || 1 0.64 0.62 0.44 0.40 -0.23 0.24 -0.39 -0.46 0.28 -0.32 -0.28 0.22 0.19 0.57 -0.09 0.15
5887 || orf19.936 || || || Ortholog of C. dubliniensis CD36 : Cd36_50530, C. parapsilosis CDC317 : CPAR2_303990, Candida tenuis NRRL Y-1498 : CANTEDRAFT_107934 and Pichia stipitis Pignal : PICST_63283 || 1 1.37 1.42 -0.37 0.87 0.26 1.07 -1.19 -1.20 1.21 0.33 -1.06 -0.02 -0.95 -0.69
5888 || orf19.3691 || TIM21 || || Component of the Translocase of the Inner Mitochondrial membrane (TIM23 complex); for protein import into mitochondria; Hap43, ketoconazole-repressed; Spider biofilm repressed || 1 0.42 0.61 0.34 0.45 0.21 0.41 -0.51 -0.50 0.33 0.32 -0.54 0.30 0.48 0.15 -0.38 -0.11
5889 || orf19.3691 || TIM21 || || Component of the Translocase of the Inner Mitochondrial membrane (TIM23 complex); for protein import into mitochondria; Hap43, ketoconazole-repressed; Spider biofilm repressed || 1 0.32 0.43 0.34 0.31 -0.26 0.12 -0.54 -0.57 0.31 0.31 -0.49 0.40 0.32 0.03 -0.43 -0.06
5890 || orf19.3691 || TIM21 || || Component of the Translocase of the Inner Mitochondrial membrane (TIM23 complex); for protein import into mitochondria; Hap43, ketoconazole-repressed; Spider biofilm repressed || 1 0.50 0.56 0.51 0.59 -0.14 0.28 -0.70 -0.70 0.25 0.06 -0.19 0.25 0.20 -0.25 -0.63 -0.21
5891 || orf19.3380 || HWP2 || || GPI-anchored, glycosylated cell wall protein; required for biofilm formation, adhesion, filamentous growth on some media; expressed in hyphae; mutant delayed in virulence; regulated by Efg1, Tup1; similar to Hwp1 and Rbt1 domains || 1 0.69 0.67 0.40 0.91 -0.87 0.39 -0.83 -0.75 0.43 0.15 -0.49 0.11 0.23 -0.15 -0.92 0.84
5892 || orf19.2906 || PGA41 || || Putative GPI-anchored protein; adhesin-like protein || 1 1.03 0.13 -0.63 1.00 -0.50 0.26 -0.43 -0.41 0.62 -0.39 -0.81 0.09 -0.13 -0.13 -0.19 -0.22
5893 || orf19.2233 || PRE2 || || Putative proteasome beta-5 subunit; macrophage-induced protein || 1 0.26 0.31 -0.14 0.44 -0.54 -0.22 -0.34 -0.32 0.14 0.38 -0.38 -0.01 -0.09 -0.14 0.03 -0.29
5894 || orf19.273 || || || Ortholog(s) have unfolded protein binding activity, role in sterol biosynthetic process and endoplasmic reticulum localization || 1 0.70 -0.06 0.14 0.66 -0.56 -0.11 -0.18 -0.24 0.16 0.36 -0.67 -0.36 0.05 -0.27 -0.21 -0.48
5895 || orf19.6003 || || || Protein of unknown function; role in intracellular signal transduction; Spider biofilm induced || 1 0.55 0.60 0.56 0.49 -1.02 -0.55 -0.47 -1.02 0.06 0.08 -1.51 -0.97 0.27 -0.55 0.10 -0.73
5896 || orf19.6003 || || || Protein of unknown function; role in intracellular signal transduction; Spider biofilm induced || 1 0.98 0.98 0.24 0.69 -0.80 -0.43 -0.23 -0.55 0.21 0.20 -1.01 -0.31 0.56 -0.67 0.50 -0.85
5897 || orf19.6003 || || || Protein of unknown function; role in intracellular signal transduction; Spider biofilm induced || 1 0.97 0.88 0.42 0.56 -0.60 -0.02 -0.25 -1.00 0.00 0.10 -0.93 -0.29 0.44 -0.68 0.75 -0.24
5898 || orf19.6003 || || || Protein of unknown function; role in intracellular signal transduction; Spider biofilm induced || 1 0.93 0.92 0.49 0.90 -0.54 0.06 -0.24 -0.59 0.16 0.13 -0.85 0.06 0.64 -0.53 0.75 -0.24
5899 || orf19.6003 || || || Protein of unknown function; role in intracellular signal transduction; Spider biofilm induced || 1 0.66 0.68 0.60 0.61 -0.64 -0.10 -0.28 -0.75 0.30 0.30 -1.10 0.11 0.30 -0.36 0.69 -0.06
5900 || orf19.2593 || BIO2 || || Putative biotin synthase; induced by high iron; repressed by ciclopirox olamine; upregulated in clinical isolates from HIV+ patients with oral candidiasis; Hap43-repressed; Spider biofilm induced || 1 1.14 1.11 1.25 1.61 -0.67 0.20 -2.06 -2.71 0.06 -1.33 -3.68 0.28 0.63 -0.59 1.14 -1.11
5901 || orf19.2593 || BIO2 || || Putative biotin synthase; induced by high iron; repressed by ciclopirox olamine; upregulated in clinical isolates from HIV+ patients with oral candidiasis; Hap43-repressed; Spider biofilm induced || 1 0.83 0.81 0.99 1.22 -0.71 0.12 -2.41 -3.17 -0.03 -1.42 -3.98 0.20 0.72 -0.79 0.97 -1.05
5902 || orf19.2587 || HNM3 || || Putative transporter; Hap43, flucytosine repressed; possibly essential, disruptants not obtained by UAU1 method; Spider biofilm induced || 1 0.24 0.07 0.96 1.49 -3.25 0.23 -3.66 -4.74 0.32 -0.62 -3.55 0.98 0.84 0.45 0.60 0.35
5903 || orf19.2587 || HNM3 || || Putative transporter; Hap43, flucytosine repressed; possibly essential, disruptants not obtained by UAU1 method; Spider biofilm induced || 1 -0.04 -0.11 0.29 2.22 -4.06 -3.95 -5.17 -6.32 -1.77 -3.07 -5.69 0.41 0.71 -0.54 0.47 -1.19
5904 || orf19.2587 || HNM3 || || Putative transporter; Hap43, flucytosine repressed; possibly essential, disruptants not obtained by UAU1 method; Spider biofilm induced || 1 0.22 0.09 -0.31 1.85 -4.27 -3.10 -5.19 -4.90 -0.74 -1.69 -5.78 1.54 0.81 -0.43 0.62 -1.18
5905 || orf19.2587 || HNM3 || || Putative transporter; Hap43, flucytosine repressed; possibly essential, disruptants not obtained by UAU1 method; Spider biofilm induced || 1 0.39 0.19 -0.43 2.27 -3.90 -2.09 -4.62 -5.16 0.12 -1.79 -4.62 0.96 0.85 -0.74 0.21 -0.88
5906 || orf19.2587 || HNM3 || || Putative transporter; Hap43, flucytosine repressed; possibly essential, disruptants not obtained by UAU1 method; Spider biofilm induced || 1 0.52 0.29 0.07 1.51 -3.64 -2.21 -5.46 -4.46 -0.83 -0.36 -4.82 0.17 0.96 0.32 0.61 -1.24
5907 || orf19.2397 || || || Predicted membrane transporter, member of the anion:cation symporter (ACS) family, major facilitator superfamily (MFS); amphotericin B, caspofungin repressed; Hap43p-repressed || 1 1.71 1.32 0.68 1.43 -2.08 -1.66 -3.17 -4.38 -0.06 -0.99 -4.49 0.00 0.61 0.85 0.22 -2.16
5908 || orf19.2397 || || || Predicted membrane transporter, member of the anion:cation symporter (ACS) family, major facilitator superfamily (MFS); amphotericin B, caspofungin repressed; Hap43p-repressed || 1 1.29 1.07 0.46 1.13 -2.19 -1.44 -2.81 -3.86 -0.04 -0.93 -3.69 0.01 0.33 0.83 -0.07 -1.39
5909 || orf19.2591 || || || Ortholog(s) have adenosylmethionine-8-amino-7-oxononanoate transaminase activity and role in biotin biosynthetic process || 1 0.62 0.67 0.26 1.37 -2.56 -2.08 -2.76 -3.12 -0.19 -1.43 -4.01 -0.33 1.09 0.62 0.17 -1.50
5910 || orf19.2591 || || || Ortholog(s) have adenosylmethionine-8-amino-7-oxononanoate transaminase activity and role in biotin biosynthetic process || 1 0.76 0.69 0.76 1.59 -1.78 -0.66 -2.00 -2.56 0.30 -0.80 -3.20 -0.32 1.00 0.60 0.33 -0.79
5911 || orf19.2590 || || || Putative dethiobiotin synthetase; transcript upregulated in clinical isolates from HIV+ patients with oral candidiasis; Hap43-repressed; GlcNAc-induced protein; Spider biofilm induced || 1 1.68 1.68 0.88 1.38 -1.75 -1.73 -2.38 -3.11 0.03 -1.09 -3.55 0.53 1.57 0.82 0.94 -0.65
5912 || orf19.2590 || || || Putative dethiobiotin synthetase; transcript upregulated in clinical isolates from HIV+ patients with oral candidiasis; Hap43-repressed; GlcNAc-induced protein; Spider biofilm induced || 1 1.89 1.87 0.77 1.96 -2.34 -2.16 -2.55 -2.98 0.07 -0.62 -3.89 0.35 1.80 0.85 0.72 -0.77
5913 || orf19.2590 || || || Putative dethiobiotin synthetase; transcript upregulated in clinical isolates from HIV+ patients with oral candidiasis; Hap43-repressed; GlcNAc-induced protein; Spider biofilm induced || 1 1.62 1.47 0.10 1.04 -2.32 -2.90 -2.92 -3.05 -0.19 -1.02 -3.80 0.83 1.53 0.98 0.50 -1.81
5914 || orf19.2590 || || || Putative dethiobiotin synthetase; transcript upregulated in clinical isolates from HIV+ patients with oral candidiasis; Hap43-repressed; GlcNAc-induced protein; Spider biofilm induced || 1 2.30 1.77 1.17 2.00 -2.21 -0.85 -1.63 -2.32 0.17 -0.58 -2.63 0.32 1.57 1.22 1.06 -0.21
5915 || orf19.3226 || || || Ortholog(s) have role in intracellular sterol transport and extracellular region, fungal-type vacuole lumen localization || 1 0.35 0.21 0.70 0.77 -0.90 -0.14 -0.98 -0.66 -0.74 -0.16 -0.61 -0.13 0.60 0.32 0.29 -0.51
5916 || orf19.1727 || PMC1 || || Vacuolar calcium P-type ATPase; transcript regulated by calcineurin and fluconazole; mutant shows increased resistance to fluconazole, lithium; increased sensitivity to calcium; Spider biofilm induced || 1 0.02 -0.00 0.61 0.80 -0.76 -0.35 0.07 -0.87 -0.01 -0.23 -0.81 -0.30 -0.09 -0.01 0.34 -0.18
5917 || orf19.1727 || PMC1 || || Vacuolar calcium P-type ATPase; transcript regulated by calcineurin and fluconazole; mutant shows increased resistance to fluconazole, lithium; increased sensitivity to calcium; Spider biofilm induced || 1 -0.04 -0.05 0.24 0.58 -0.76 -0.35 0.05 -0.86 0.23 0.07 -0.71 -0.14 0.19 0.57 0.52 -0.21
5918 || orf19.1727 || PMC1 || || Vacuolar calcium P-type ATPase; transcript regulated by calcineurin and fluconazole; mutant shows increased resistance to fluconazole, lithium; increased sensitivity to calcium; Spider biofilm induced || 1 -0.12 -0.39 0.23 0.54 -0.97 -0.46 0.13 -0.90 0.27 0.05 -0.88 -0.13 0.29 0.38 0.49 -0.08
5919 || orf19.5908 || TEC1 || || TEA/ATTS transcription factor; white cell pheromone response, hyphal gene regulation; required for Spider and RPMI biofilm formation; regulates BCR1; Cph2 regulated transcript; alkaline, rat catheter, Spider, flow model biofilm induced || 1 -0.00 0.23 0.08 -0.05 -0.37 0.14 -0.27 -0.64 -0.06 -0.37 -0.26 0.19 0.51 -0.06 0.14 -0.41
5920 || orf19.6374 || || || Ortholog(s) have unfolded protein binding activity, role in mitochondrial proton-transporting ATP synthase complex assembly and integral to mitochondrial membrane, mitochondrial inner membrane localization || 1 -0.23 -0.06 0.04 0.15 0.15 -0.28 -0.54 -0.39 -0.16 -0.58 -0.35 0.30 -0.03 -0.16 -0.14 -0.19
5921 || orf19.4846 || || || GlcNAc-induced protein || 1 -0.14 0.21 0.05 0.09 0.10 -0.01 -0.54 -0.50 0.12 -0.39 -0.33 0.16 0.26 -0.42 -0.30 -0.36
5922 || orf19.4131 || || || Ortholog(s) have role in protein folding in endoplasmic reticulum and ER membrane protein complex localization || 1 -0.11 0.01 -0.14 -0.14 0.02 -0.26 -0.09 -0.24 0.04 -0.19 -0.33 -0.02 0.12 -0.18 -0.04 -0.15
5923 || orf19.5586 || || || Ortholog(s) have phosphatidylinositol-3,5-bisphosphate 5-phosphatase activity, role in phosphatidylinositol dephosphorylation and PAS complex, cytosol, extrinsic to membrane, fungal-type vacuole membrane localization || 1 0.33 0.30 -0.09 0.05 0.14 -0.63 -0.21 -0.53 -0.27 -0.78 -0.62 -0.07 0.41 -0.23 -0.13 0.08
5924 || orf19.7281 || PDK2 || || Putative pyruvate dehydrogenase kinase; mutation confers hypersensitivity to amphotericin B || 1 0.85 0.66 -0.13 -0.39 -0.30 -0.52 -0.14 -0.12 -0.30 -0.50 -0.73 -0.52 -0.34 -0.28 0.69 -0.23
5925 || orf19.7281 || PDK2 || || Putative pyruvate dehydrogenase kinase; mutation confers hypersensitivity to amphotericin B || 1 0.81 0.60 -0.06 -0.08 -0.38 -0.33 -0.43 -0.36 -0.30 -0.47 -0.83 -0.04 -0.56 -0.29 0.58 -0.11
5926 || orf19.7281 || PDK2 || || Putative pyruvate dehydrogenase kinase; mutation confers hypersensitivity to amphotericin B || 1 0.51 0.42 0.05 0.00 -0.37 -0.53 -0.58 -0.55 -0.20 -0.57 -0.90 -0.68 -0.42 -0.75 0.31 -0.53
5927 || orf19.7281 || PDK2 || || Putative pyruvate dehydrogenase kinase; mutation confers hypersensitivity to amphotericin B || 1 0.43 0.42 0.02 -0.15 -0.10 -0.41 -0.29 -0.28 0.08 -0.19 -0.64 -0.18 0.01 -0.11 0.51 -0.76
5928 || orf19.5859 || DAL8 || || Putative allantoate permease; fungal-specific (no human or murine homolog) || 1 0.14 1.94 0.37 0.41 -0.07 -1.63 0.06 -0.21 0.06 -0.22 0.44 -0.39 0.21 -0.29 0.12 -1.29
5929 || orf19.4821 || LIP1 || || Secreted lipase, member of a lipase gene family whose members are expressed differentially in response to carbon source and during infection; may have a role in nutrition and/or in creating an acidic microenvironment || 1 0.99 1.23 1.56 2.74 -0.04 -3.67 0.13 -0.64 -1.59 -0.56 -0.70 -0.54 -0.69 -1.23 0.02
5930 || orf19.7447 || JEN1 || || Lactate transporter; induced by lactic acid, activated by Cat8; alkaline repressed by Rim101; localizes to plasma membrane; Spider biofilm induced || 1 1.65 1.13 1.39 2.87 -0.22 -5.06 -0.23 -0.38 -1.29 0.07 -0.44 -1.68 -0.71 -1.21 -0.31
5931 || orf19.2481 || || || Protein of unknown function; Spider biofilm induced || 1 0.54 0.69 0.83 1.23 0.82 -3.37 -0.68 -0.40 -0.17 -0.64 -0.78 -0.42 -0.30 -0.65 -0.38 -1.16
5932 || orf19.7195 || RAD6 || || Functional ortholog of S. cerevisiae Rad6; negative regulator of hyphal growth; required for wild-type UV resistance; acts in pathway with Efg1; ; transcript is UV-induced, slightly repressed during hyphal growth; gene has two introns || 1 0.08 0.01 -0.04 0.26 0.10 -0.55 0.01 0.35 -0.19 -0.05 0.04 -0.23 0.17 -0.12 0.02 -0.36
5933 || orf19.7402 || DOT1 || || Putative modulator of white-opaque switching || 1 -0.02 0.04 0.20 0.14 0.17 -0.69 0.03 0.36 -0.02 0.08 0.22 -0.26 0.31 0.18 -0.15 -0.23
5934 || orf19.5873 || POL1 || || Putative DNA directed DNA polymerase alpha; RNA abundance regulated by cell cycle, tyrosol and cell density; rat catheter biofilm induced || 1 0.07 0.59 0.40 0.24 0.47 -0.97 -0.33 0.21 -0.22 0.56 0.31 -0.47 0.53 0.47 -0.51 -0.41
5935 || orf19.7065 || PSF3 || || Putative GINS complex subunit; cell-cycle regulated periodic mRNA expression; Spider biofilm induced || 1 0.26 0.87 0.65 0.51 0.49 -1.26 -0.34 0.23 -0.58 0.96 -0.01 -0.03 0.40 0.31 0.09 -0.58
5936 || orf19.7065 || PSF3 || || Putative GINS complex subunit; cell-cycle regulated periodic mRNA expression; Spider biofilm induced || 1 0.54 0.59 0.21 0.27 0.22 -1.24 -0.28 -0.00 -0.87 0.37 0.10 -0.34 -0.04 0.09 -0.60 -0.88
5937 || orf19.1533 || || || Possible vacuolar protein; Hap43-induced gene || 1 0.38 0.31 0.23 0.12 0.15 -0.88 -0.10 0.32 -0.60 0.11 0.22 -0.41 0.41 -0.17 0.01 -0.55
5938 || orf19.4741 || || || Protein of unknown function; C. albicans- and C. dubliniensis specific gene; rat catheter biofilm repressed || 1 0.51 0.29 0.40 0.45 -0.05 -0.53 -0.10 0.42 -0.70 0.46 0.44 0.46 0.04
5939 || orf19.6434 || PEX19 || || Ortholog(s) have peroxisome membrane targeting sequence binding activity || 1 0.63 0.73 0.27 0.64 0.03 -0.69 0.05 0.54 -0.66 0.41 -0.16 -0.63 -0.26 -0.73 0.04 -0.52
5940 || orf19.4457 || BNI4 || || Protein required for wild-type cell wall chitin distribution, morphology, hyphal growth; not essential; similar to S. cerevisiae Bni4p (targeting subunit for Glc7p phosphatase, involved in bud-neck localization of chitin synthase III) || 1 0.64 0.60 0.01 0.16 -0.12 -0.79 0.58 0.33 -0.24 0.04 -0.06 -0.80 0.50 -0.05 -0.08 -0.18
5941 || orf19.2936 || || || Ortholog of C. parapsilosis CDC317 : CPAR2_106450, C. dubliniensis CD36 : Cd36_02330, Lodderomyces elongisporus NRLL YB-4239 : LELG_01618 and Candida orthopsilosis Co 90-125 : CORT_0B07690 || 1 1.20 1.18 0.21 0.62 -0.88 -2.05 0.06 0.51 -0.10 0.24 -1.03 -1.40 0.17 -1.02 -0.37 -1.56
5942 || orf19.4066 || || || Putative glycerol-3-phosphate acyltransferase; Hog1-repressed || 1 1.51 1.43 0.34 0.60 -0.72 -1.75 0.28 0.36 -0.92 0.14 -0.51 -1.35 0.49 0.17 -0.57 -1.35
5943 || orf19.4066 || || || Putative glycerol-3-phosphate acyltransferase; Hog1-repressed || 1 1.33 1.30 0.58 1.03 -0.86 -1.57 0.17 0.66 -0.72 0.30 -0.47 -0.89 0.18 0.77 -0.68 -0.65
5944 || orf19.6724 || FUM12 || || Putative fumarate hydratase; enzyme of citric acid cycle; fluconazole, Efg1 repressed; induced in high iron; protein present in exponential and stationary growth phase || 1 0.42 0.50 0.19 0.19 -0.14 -1.08 0.23 0.51 0.04 0.25 -0.59 -0.57 0.10 0.41 -0.35 -0.68
5945 || orf19.1761 || || || Predicted olichyl-diphosphooligosaccharide-protein glycotransferase; role in protein N-linked glycosylation; Spider biofilm repressed || 1 0.26 0.37 0.39 0.22 -0.13 -0.41 -0.18 0.03 0.15 0.26 0.00 0.35 0.38 0.44 -0.55 0.03
5946 || orf19.2928 || || || Ortholog(s) have COPI-coated vesicle, Golgi apparatus localization || 1 0.04 0.25 0.47 0.32 -0.28 -0.29 -0.05 -0.04 0.22 0.72 -0.25 0.26 0.23 0.15 -0.76 -0.03
5947 || orf19.7632 || || || Ortholog of C. dubliniensis CD36 : Cd36_35360, C. parapsilosis CDC317 : CPAR2_200320, Candida tenuis NRRL Y-1498 : CANTEDRAFT_136418 and Debaryomyces hansenii CBS767 : DEHA2A14080g || 1 0.02 0.27 0.44 0.57 -0.28 -0.44 -0.08 0.13 0.26 0.36 -0.24 -0.34 -0.05 0.13 -0.68 -0.07
5948 || orf19.6072 || CDC13 || || Essential protein with similarity to S. cerevisiae Cdc13p, involved in telomere maintenance || 1 0.16 0.76 0.38 0.94 -0.37 -1.04 -0.10 0.38 0.24 0.57 -0.16 -0.13 0.03 0.05 -0.65 -0.19
5949 || orf19.3823 || ZDS1 || || Nonessential protein; similar to S. cerevisiae Zds1p || 1 0.37 0.21 0.42 0.69 -0.29 -0.94 -0.11 0.10 0.24 0.42 0.13 -0.33 0.42 -0.02 -0.46 -0.03
5950 || orf19.4865 || || || Ortholog(s) have phosphatidylinositol-3,5-bisphosphate 5-phosphatase activity, phosphatidylinositol-3-phosphatase activity, phosphatidylinositol-4-phosphate phosphatase activity and role in phosphatidylinositol dephosphorylation || 1 0.27 0.28 0.25 0.60 -0.42 -0.62 0.05 0.21 0.36 0.51 0.13 0.22 0.23 -0.04 -0.60 -0.28
5951 || orf19.4069 || || || Protein of unknown function; repressed by alpha pheromone in SpiderM medium || 1 0.57 0.75 0.68 0.78 -0.77 -0.60 -0.17 0.49 1.21 0.97 -0.27 0.77 -0.28 -0.81
5952 || orf19.1251 || BRN1 || || Putative condensin complex subunit; cell-cycle regulated periodic mRNA expression || 1 0.34 0.79 0.64 0.57 -0.26 -0.57 -0.17 -0.12 0.19 0.24 -0.24 -0.03 0.38 0.12 -0.65 -0.63
5953 || orf19.2928 || || || Ortholog(s) have COPI-coated vesicle, Golgi apparatus localization || 1 0.17 0.05 0.50 0.64 -0.53 -0.36 -0.41 -0.26 0.22 0.67 -0.41 0.37 -0.09 0.08 -0.53 -0.40
5954 || orf19.2928 || || || Ortholog(s) have COPI-coated vesicle, Golgi apparatus localization || 1 0.26 -0.06 0.76 0.67 -0.38 -0.53 -0.08 -0.23 0.27 0.57 -0.44 0.18 -0.22 0.13 -0.68 -0.16
5955 || orf19.316 || SEC13 || || Putative protein transport factor; antigenic during murine systemic infection; macrophage-downregulated protein; protein level decreases in stationary phase cultures; Spider biofilm repressed || 1 -0.12 0.03 0.40 0.30 -0.31 -0.67 -0.31 -0.17 -0.01 0.32 -0.19 -0.01 -0.12 0.12 -0.35 0.09
5956 || orf19.2928 || || || Ortholog(s) have COPI-coated vesicle, Golgi apparatus localization || 1 -0.12 -0.08 0.68 0.51 -0.46 -0.60 -0.45 -0.36 -0.10 0.54 -0.53 0.01 -0.05 0.15 -0.41 -0.01
5957 || orf19.2928 || || || Ortholog(s) have COPI-coated vesicle, Golgi apparatus localization || 1 -0.00 -0.08 0.59 0.39 -0.64 -0.69 -0.64 -0.28 -0.12 0.56 -0.55 0.22 -0.20 0.21 -0.75 -0.40
5958 || orf19.708 || || || Ortholog(s) have structural constituent of cytoskeleton activity || 1 -0.28 -0.03 0.54 0.60 -0.81 -0.78 -0.53 -0.26 -0.21 0.29 -0.47 -0.04 -0.05 0.47 -1.18 -0.15
5959 || orf19.972 || || || Ortholog(s) have 5'-flap endonuclease activity, role in DNA-dependent DNA replication and Slx1-Slx4 complex localization || 1 -0.00 -0.29 0.11 0.14 -0.68 -0.72 -0.21 0.03 0.44 0.14 -0.39 -0.55 -0.02 0.50 -0.82 -0.12
5960 || orf19.7181 || || || Ortholog of C. dubliniensis CD36 : Cd36_73670, C. parapsilosis CDC317 : CPAR2_702370, Candida tenuis NRRL Y-1498 : CANTEDRAFT_119320 and Debaryomyces hansenii CBS767 : DEHA2G16632g || 1 -0.03 -0.25 0.59 0.57 -0.64 -0.66 -0.04 0.11 0.54 0.10 -0.24 -0.59 -0.13 0.20 -0.50 -0.45
5961 || orf19.3366 || CSH3 || || Functional homolog of S. cerevisiae Shr3p, which is a chaperone specific for amino acid permeases; localized to ER; required for wild-type amino-acid responsive hyphal growth and for mouse systemic virulence; regulated by Gcn2p and Gcn4p || 1 0.04 0.00 0.40 0.50 -1.14 -0.63 -0.29 -0.22 0.34 0.19 -0.68 -0.20 0.04 0.26 -0.14 -0.36
5962 || orf19.1490 || MSB2 || || Mucin family adhesin-like protein; cell wall damage sensor; required for Cek1 phosphorylation by cell wall stress; Rim101-repressed; activation releases extracellular domain into medium; Spider biofilm induced || 1 0.08 0.06 0.49 0.70 -1.16 -1.30 -0.09 0.02 0.39 0.48 -0.58 -0.10 0.17 0.36 -0.72 -0.50
5963 || orf19.6480 || || || Ortholog(s) have role in UDP-glucose transport and COPI-coated vesicle, Golgi apparatus localization || 1 0.15 0.02 0.59 1.14 -1.13 -0.97 -0.12 0.28 0.68 0.31 -0.88 -0.12 0.01 0.49 -0.77 -0.60
5964 || orf19.6480 || || || Ortholog(s) have role in UDP-glucose transport and COPI-coated vesicle, Golgi apparatus localization || 1 0.29 0.12 0.77 1.25 -1.09 -1.01 -0.17 0.28 0.67 0.54 -0.72 -0.45 0.16 0.50 -0.98 -0.60
5965 || orf19.4242 || CST20 || || Protein kinase of Ste20p/p65PAK family, required for wild-type mating efficiency and virulence in a mouse model; Cst20p-Hst7p-Cek1p-Cph1p MAPK pathway regulates some hyphal growth; involved in Cdc42p growth regulation || 1 0.39 0.20 0.41 0.81 -0.53 -0.56 -0.14 -0.00 0.24 0.41 -0.53 -0.16 0.14 0.36 -0.68 -0.45
5966 || orf19.4923 || || || Predicted membrane transporter; sugar porter (SP) family member, major facilitator superfamily; caspofungin induced; Spider biofilm induced || 1 0.36 0.30 0.36 0.84 -0.92 -1.13 -0.45 -0.44 0.44 0.12 -0.23 -0.43 0.25 0.42 -0.76 0.34
5967 || orf19.4923 || || || Predicted membrane transporter; sugar porter (SP) family member, major facilitator superfamily; caspofungin induced; Spider biofilm induced || 1 0.22 0.41 0.87 0.39 -1.64 -1.14 -0.07 -0.62 0.48 -0.11 -0.78 -0.55 0.40 1.18 -0.68 -0.07
5968 || orf19.782 || || || Ortholog(s) have serine hydrolase activity, triglyceride lipase activity, role in lipid homeostasis and lipid particle localization || 1 0.28 0.16 0.44 0.40 -0.61 -0.64 0.34 0.25 0.64 0.35 -0.79 -0.36 0.06 0.65 0.10 -0.08
5969 || orf19.1414 || || || Protein of unknown function; transcript is upregulated in an RHE model of oral candidiasis; Hap43-repressed || 1 0.06 0.15 0.22 0.39 -0.32 -0.36 0.13 0.14 0.19 0.27 -0.30 -0.03 0.03 0.35 -0.07 -0.17
5970 || orf19.2888 || || || Ortholog(s) have role in early endosome to Golgi transport, protein complex assembly and Golgi apparatus, TRAPP complex, clathrin-coated vesicle localization || 1 0.06 0.37 0.38 0.58 -0.13 -0.55 -0.18 0.05 0.56 0.66 -0.44 -0.15 0.09 0.75 -0.20 -0.10
5971 || orf19.660 || || || Protein of unknown function; mRNA binds She3 || 1 0.37 0.56 0.68 0.56 -0.13 -0.60 0.01 0.24 0.00 0.40 -0.86 -0.06 0.73 0.91 -0.77 -0.73
5972 || orf19.1842 || BUD5 || || Predicted GTP/GDP exchange factor for Rsr1; rat catheter biofilm induced || 1 0.47 0.50 0.84 0.61 -0.54 -1.05 0.14 -0.08 0.39 0.42 -0.41 -0.29 0.88 0.92 -0.63 -0.37
5973 || orf19.2888 || || || Ortholog(s) have role in early endosome to Golgi transport, protein complex assembly and Golgi apparatus, TRAPP complex, clathrin-coated vesicle localization || 1 0.17 0.56 0.53 0.43 0.01 -0.39 0.06 0.01 0.85 0.44 -0.57 -0.28 0.53 0.57 -0.40 -0.24
5974 || orf19.2888 || || || Ortholog(s) have role in early endosome to Golgi transport, protein complex assembly and Golgi apparatus, TRAPP complex, clathrin-coated vesicle localization || 1 0.31 0.48 0.39 0.44 -0.28 -0.56 -0.04 0.06 0.80 0.56 -0.71 -0.00 0.36 0.77 -0.47 -0.49
5975 || orf19.2888 || || || Ortholog(s) have role in early endosome to Golgi transport, protein complex assembly and Golgi apparatus, TRAPP complex, clathrin-coated vesicle localization || 1 0.14 0.45 0.29 0.52 -0.08 -0.41 0.10 -0.05 0.82 0.29 -0.61 -0.15 0.44 0.53 -0.44 -0.52
5976 || orf19.2888 || || || Ortholog(s) have role in early endosome to Golgi transport, protein complex assembly and Golgi apparatus, TRAPP complex, clathrin-coated vesicle localization || 1 0.21 0.59 0.48 0.42 -0.17 -0.45 0.14 0.09 0.71 0.42 -0.61 -0.02 0.54 0.68 -0.37 -0.86
5977 || orf19.4568 || ZCF25 || || Putative Zn(II)2Cys6 transcription factor || 1 0.49 0.91 0.91 0.60 -0.19 -0.95 0.53 0.49 0.97 0.72 -1.03 -0.60 0.54 0.58 -0.29 -1.77
5978 || orf19.1888 || || || Putative nicotinamide riboside hydrolase; cleaves N-glycosidic bonds in nucleosides; pyrimidine salvage and nicotinamide riboside salvage pathways; Spider biofilm induced || 1 0.13 0.32 0.38 0.36 0.00 -0.92 0.15 0.24 0.79 0.34 -0.44 -0.52 0.38 0.27 -0.43 -0.85
5979 || orf19.4607 || || || Possible Golgi membrane protein; Hap43-repressed; hypha induced; flow model biofilm induced; Spider biofilm induced || 1 0.16 0.46 0.82 0.69 0.03 -0.42 0.14 0.23 1.03 0.13 -0.75 -1.04 0.75 0.38 -0.37 -1.14
5980 || orf19.5139 || || || Ortholog of C. dubliniensis CD36 : Cd36_72800, Candida tropicalis MYA-3404 : CTRG_05211 and Candida albicans WO-1 : CAWG_05649 || 1 0.01 0.16 0.60 0.56 -0.17 -0.56 -0.04 0.15 0.50 0.17 -0.34 -0.40 0.13 0.17 -0.43 -0.64
5981 || orf19.1424 || || || Predicted membrane transporter, member of the oxalate:formate antiporter (OFA) family, major facilitator superfamily (MFS) || 1 -0.11 -0.09 0.80 1.05 -0.21 -0.13 0.24 0.40 0.96 0.23 -0.82 -0.19 0.57 0.69 -0.59 -0.94
5982 || orf19.1599 || || || Ortholog of Candida albicans WO-1 : CAWG_06018 || 1 -0.15 -0.07 0.22 0.61 -0.88 -0.17 -0.14 0.29 1.35 0.46 -1.29 -0.50 0.59 0.76 -0.49 -0.85
5983 || orf19.6114 || || || Protein of unknown function; transcript detected on high-resolution tiling arrays || 1 -0.46 -0.19 1.09 0.64 -0.80 0.03 -0.96 -0.21 1.44 0.78 -0.35 -0.88 0.60 1.48 -0.57 -0.50
5984 || orf19.3871 || DAD3 || || Subunit of the Dam1 (DASH) complex, which acts in chromosome segregation by coupling kinetochores to spindle microtubules || 1 -0.03 0.21 1.09 0.60 -0.26 0.01 -0.19 0.05 0.79 0.50 -0.35 -0.27 0.45 0.41 -0.76 -0.09
5985 || orf19.5574 || || || Ortholog(s) have mitochondrial outer membrane localization || 1 0.02 0.35 0.78 0.45 -0.21 -0.11 -0.44 -0.34 0.34 0.24 -0.60 -0.53 0.37 0.15 -0.70 -0.37
5986 || orf19.4264 || || || Protein of unknown function; induced during chlamydospore formation in both C. albicans and C. dubliniensis; flow model biofilm induced || 1 -0.08 0.11 0.34 0.58 -0.18 -0.94 -0.14 0.17 -0.03 -0.52 -0.41 -0.13 0.20 -0.04 -0.26 -0.58
5987 || orf19.1651 || || || Ortholog of C. dubliniensis CD36 : Cd36_81960, Pichia stipitis Pignal : psti_CGOB_00163, Candida tropicalis MYA-3404 : CTRG_02378 and Candida albicans WO-1 : CAWG_02525 || 1 0.48 0.68 0.95 0.78 -0.41 -1.45 -0.07 0.12 0.52 -0.42 -0.31 -0.43 0.19 0.59 -0.57 -0.77
5988 || orf19.2150 || || || Putative ortholog of mammalian electron transfer flavoprotein complex subunit ETF-alpha; Spider biofilm repressed || 1 0.00 0.22 0.02 0.43 -0.09 -0.74 -0.02 0.16 0.27 -0.02 -0.04 -0.17 -0.12 0.00 -0.57 -0.53
5989 || orf19.191 || KIC1 || || Member of the GCK-III subfamily of eukaryotic Ste20p kinases; in RAM cell wall integrity signaling network; role in cell separation, azole sensitivity; required for hyphal growth; constitutive expression is MTL, white-opaque independent || 1 0.21 0.11 0.14 0.11 -0.20 -0.31 0.08 0.14 0.08 -0.17 -0.33 -0.19 -0.09 -0.10 -0.05 -0.08
5990 || orf19.3142 || || || Ortholog of C. dubliniensis CD36 : Cd36_46140, C. parapsilosis CDC317 : CPAR2_501210, Candida tenuis NRRL Y-1498 : CANTEDRAFT_97195 and Debaryomyces hansenii CBS767 : DEHA2E08800g || 1 0.13 0.23 0.34 0.21 -0.56 -0.70 0.56 -0.04 0.99 -0.98 -0.94 -0.34 0.36 0.31 -0.59 -0.19
5991 || orf19.5809 || || || Putative arylformamidase, enzyme of the NAD biosynthesis pathway; Gcn4p-regulated || 1 0.10 -0.10 0.55 0.71 -1.54 -1.63 0.47 0.24 0.72 -0.78 -0.79 -0.23 -0.26 0.22 -0.74 -0.51
5992 || orf19.5809 || || || Putative arylformamidase, enzyme of the NAD biosynthesis pathway; Gcn4p-regulated || 1 -0.01 0.09 0.40 0.39 -1.59 -1.29 0.76 0.35 0.72 -0.70 -0.63 -0.05 -0.17 0.29 -0.46 -0.30
5993 || orf19.3365 || DAO2 || || Putative D-amino acid oxidase; rat catheter biofilm induced || 1 -0.05 0.16 0.41 0.20 -0.50 -0.60 0.47 0.50 0.70 -0.51 -0.41 -0.30 0.02 0.21 -0.30 -0.48
5994 || orf19.6899 || || || Putative oxidoreductase; mutation confers hypersensitivity to toxic ergosterol analog; rat catheter and Spider biofilm induced || 1 -0.23 -0.10 0.95 1.07 -1.28 -1.59 1.08 -0.04 1.33 -1.30 -1.98 -1.34 -0.47 0.35 -1.24 -2.40
5995 || orf19.6899 || || || Putative oxidoreductase; mutation confers hypersensitivity to toxic ergosterol analog; rat catheter and Spider biofilm induced || 1 0.16 0.07 0.66 1.27 -1.03 -0.70 0.54 -0.02 0.78 -0.99 -0.98 -0.72 -0.25 -0.14 -0.55 -0.92
5996 || orf19.276 || || || Plasma membrane-associated protein; upregulated in an azole-resistant strain that overexpresses MDR1; Hap43-repressed; Spider biofilm induced || 1 -0.10 -0.27 0.40 0.76 -0.62 -0.71 0.30 0.03 0.44 -0.93 -0.26 -0.19 -0.48 -0.13 -0.28 -0.05
5997 || orf19.7305 || || || Ortholog of C. dubliniensis CD36 : Cd36_34510, Candida tropicalis MYA-3404 : CTRG_05938 and Candida albicans WO-1 : CAWG_02183 || 1 0.16 -0.03 0.85 0.72 -0.70 -0.24 -0.17 -0.32 0.45 -0.12 -0.77 -0.42 -0.49 0.07 -0.37 -0.27
5998 || orf19.4589 || || || Ortholog(s) have polyamine oxidase activity, role in pantothenate biosynthetic process, polyamine catabolic process and cytoplasm localization || 1 0.45 -0.04 0.95 0.98 -0.59 -0.15 0.12 0.08 0.44 0.00 -0.51 -0.51 -0.19 0.36 -0.60 -0.09
5999 || orf19.4571 || || || CoA-transferase family protein; rat catheter biofilm repressed || 1 0.43 0.49 1.42 0.88 -1.18 -0.10 0.38 0.32 1.15 -0.12 -1.22 -1.23 -0.11 0.80 -0.89 0.17
6000 || orf19.3419 || MAE1 || || Malic enzyme, mitochondrial; transcription regulated by Mig1, Tup1; colony morphology-related gene regulation by Ssn6; Hap43-repressed; Spider biofilm repressed || 1 0.13 0.13 0.94 0.81 -0.57 -0.02 0.08 0.63 0.06 -0.70 -1.19 -1.10 0.25 0.02 -1.41 -0.52
6001 || orf19.6574 || ALK6 || || Putative cytochrome P-450 of N-alkane-induced detoxification; macrophage-induced gene || 1 -0.61 -0.69 1.03 0.95 -0.55 -0.11 0.34 -0.37 0.89 -0.74 -1.22 -1.29 0.60 0.15 -1.05 -0.65
6002 || orf19.7379 || FAA2 || || Putative acyl CoA synthetase; expression regulated upon white-opaque switch; rat catheter biofilm induced; Spider biofilm induced || 1 -0.10 -0.11 0.76 0.75 -0.41 -0.68 0.32 0.07 0.36 -0.19 -0.81 -0.61 0.53 0.20 -0.29 -0.63
6003 || orf19.4264 || || || Protein of unknown function; induced during chlamydospore formation in both C. albicans and C. dubliniensis; flow model biofilm induced || 1 0.01 0.04 0.52 0.38 -0.42 -0.12 -0.16 0.00 0.45 -0.26 -0.61 -0.59 0.16 0.58 -0.27 -0.76
6004 || orf19.310 || || || Putative mitochondrial protein with a predicted role in cell wall biogenesis; possibly an essential gene, disruptants not obtained by UAU1 method || 1 -0.18 -0.08 0.74 0.68 -0.44 -0.31 0.59 0.17 0.95 0.35 0.11 -0.53 0.02 0.75 -0.75 -0.15
6005 || orf19.3436 || || || Protein with a Rho GDP-dissociation inhibitor domain; macrophage-induced gene || 1 0.23 -0.18 0.17 0.19 -0.30 -0.30 0.28 0.24 0.58 0.26 0.12 -0.02 0.31 0.63 -0.41 -0.08
6006 || orf19.1715 || IRO1 || || Putative transcription factor; role in iron utilization, pathogenesis; both IRO1 and adjacent URA3 are mutated in strain CAI4; suppresses S. cerevisiae aft1 mutant low-iron growth defect; hyphal-induced; reports differ about iron regulation || 1 0.16 0.27 0.28 0.16 -0.49 -0.65 0.57 0.32 0.77 0.53 -0.09 -0.26 0.37 0.37 -0.54 0.53
6007 || orf19.7301 || || || Has domain(s) with predicted DNA binding activity || 1 0.15 0.01 0.61 0.74 -0.81 -0.60 0.65 0.78 0.72 0.60 -0.47 -0.47 0.19 0.49 -0.53 0.22
6008 || orf19.6958 || ECM18 || || Ortholog(s) have mitochondrion localization || 1 0.26 0.44 0.45 0.76 -1.08 -1.05 0.71 1.21 0.64 0.65 -0.20 -0.62 0.50 0.67 -0.47 0.01
6009 || orf19.3134 || || || Protein of unknown function; flow model biofilm induced || 1 0.69 0.54 0.81 0.31 -0.50 -0.29 0.57 0.58 1.11 0.03 -0.11 -1.25 0.61 0.47 0.34 -0.10
6010 || orf19.1158 || || || Ortholog of S. cerevisiae Yft2 required for normal ER membrane biosynthesis; Hap43-repressed gene || 1 0.37 0.12 0.56 0.23 -0.38 -0.21 0.05 0.60 0.99 0.10 -0.20 -0.21 0.20 0.30 -0.21 -0.05
6011 || orf19.1497 || ZCF6 || || Putative transcription factor with zinc cluster DNA-binding motif || 1 0.51 0.10 0.64 0.27 -0.40 0.33 0.79 0.65 1.13 0.08 -0.14 0.02 0.35 0.40 0.04 -0.47
6012 || orf19.4284 || BUR2 || || Protein with similarity to S. cerevisiae Bur2p, contains a cyclin domain; not required for wild-type hyphal growth, adherence to buccal epithelial cells, or virulence in mouse systemic infection || 1 0.11 0.13 0.34 0.50 -0.36 0.18 0.15 -0.20 0.64 0.31 -0.30 0.25 -0.04 0.39 -0.25 -0.17
6013 || orf19.944 || IFG3 || || Putative D-amino acid oxidase; Spider biofilm induced || 1 0.19 0.13 0.71 0.78 -0.13 0.19 0.77 0.21 1.03 0.25 -0.85 -0.17 -0.39 0.61 0.11 -0.08
6014 || orf19.4894 || || || Protein with similarity to S. cerevisiae Yer010cp, a protein of unknown function belonging to the prokaryotic RraA family; repressed by benomyl; Hap43-induced; Spider biofilm induced || 1 -0.08 0.45 0.91 0.55 -0.26 0.16 0.71 -0.03 1.11 0.17 -1.07 -0.57 -0.37 0.34 -0.89 -1.16
6015 || orf19.4571 || || || CoA-transferase family protein; rat catheter biofilm repressed || 1 0.21 0.62 0.73 0.76 -0.17 0.01 -0.17 0.19 -0.89 -0.56 -0.12 0.96 -1.71
6016 || orf19.5266 || || || Planktonic growth-induced gene || 1 0.66 0.62 0.38 0.97 0.22 0.44 -0.05 0.14 0.17 0.20 -0.56 -0.40 0.01 0.60 -0.82 -0.24
6017 || orf19.3711 || || || Protein with monooxygenase domains; flow model biofilm induced || 1 0.62 0.56 1.06 0.76 -0.03 0.49 0.13 -0.17 0.21 0.28 -0.96 -0.23 -0.16 0.52 -0.42 -0.52
6018 || orf19.6907 || || || Ortholog(s) have DNA binding activity and cytoplasm, nuclear chromatin localization || 1 -0.15 -0.33 0.75 0.46 -0.50 -0.23 -0.19 -0.09 0.59 0.63 -0.13 -0.00 -0.30 0.04 -0.65 -0.51
6019 || orf19.7494 || || || Protein of unknown function; cell-cycle regulated periodic mRNA expression || 1 -0.33 -0.20 0.50 0.20 -0.25 -0.36 -0.38 -0.14 0.13 0.36 -0.17 -0.40 -0.18 0.39 -0.78 -0.57
6020 || orf19.3311 || IFD3 || || Putative aldo/keto reductase; Mig1-regulated || 1 0.15 0.12 0.82 0.62 -0.40 -0.80 0.28 0.42 0.57 0.61 -0.63 -0.74 -0.52 0.26 -0.22 -0.38
6021 || orf19.30 || SPF1 || || P-type calcium-transporting ATPase, involved in control of calcium homeostasis, response to ER stress, hyphal growth, biofilm formation and virulence || 1 0.20 0.40 0.63 0.34 -0.50 -0.87 0.14 0.32 0.03 0.43 -0.19 -0.31 -0.44 0.23 -0.33 -0.21
6022 || orf19.3782 || || || Predicted membrane transporter; member of the peptide-acetyl-coA transporter (PAT) family, major facilitator superfamily (MFS); induced by alpha pheromone in Spider medium || 1 0.30 -0.01 0.82 0.48 -0.53 -0.60 0.08 0.34 -0.07 0.56 -0.47 -0.06 -0.08 0.38 -0.00 0.16
6023 || orf19.2298 || WBP1 || || Putative oligosaccharyltransferase subunit; Spider biofilm repressed || 1 0.35 0.23 0.39 0.27 -0.19 -0.86 0.33 0.44 -0.12 0.38 0.04 0.08 -0.36 0.06 -0.18 0.07
6024 || orf19.433 || || || Ortholog(s) have Rab guanyl-nucleotide exchange factor activity, role in intra-Golgi vesicle-mediated transport, protein complex assembly and TRAPP complex, trans-Golgi network localization || 1 0.04 0.01 0.48 0.42 -0.41 -0.76 -0.16 0.32 0.19 0.17 -0.15 0.31 -0.31 0.02 -0.05 0.10
6025 || orf19.5352 || || || Protein with a predicted magnesium transporter domain; mutants are viable || 1 0.13 0.08 0.28 0.46 -0.43 -0.85 0.14 0.26 0.25 0.37 0.04 0.21 -0.21 0.17 0.04 0.16
6026 || orf19.6496 || TRS33 || || Putative TRAPP complex subunit; constitutive expression independent of MTL or white-opaque status || 1 0.48 0.40 0.45 0.73 -0.96 -0.85 0.00 -0.02 0.09 0.44 0.10 0.05 -0.43 0.38 0.02 0.02
6027 || orf19.7426 || || || Ortholog(s) have dolichyl-diphosphooligosaccharide-protein glycotransferase activity, role in protein N-linked glycosylation via asparagine, protein complex assembly and oligosaccharyltransferase complex localization || 1 0.00 0.78 -0.04 0.29 -0.95 -1.43 0.14 0.26 -0.04 0.51 -0.15 0.15 -0.48 0.34 -0.42 0.12
6028 || orf19.1684 || || || Ortholog of C. dubliniensis CD36 : Cd36_81500, C. parapsilosis CDC317 : CPAR2_503620, Candida tenuis NRRL Y-1498 : CANTEDRAFT_93693 and Debaryomyces hansenii CBS767 : DEHA2D15268g || 1 0.36 0.23 0.40 0.40 -0.32 -0.72 -0.03 0.14 -0.14 0.33 -0.01 0.15 0.37 0.26 -0.13 0.12
6029 || orf19.6812 || PMT2 || || Protein mannosyltransferase (PMT) with roles in hyphal growth and drug sensitivity; member of the PMT family which includes Pmt1p, Pmt2p, Pmt4p, Pmt5p, and Pmt6p; induced during cell wall regeneration; essential || 1 0.06 0.03 0.73 0.48 -0.76 -0.96 0.26 0.37 -0.30 0.12 0.29 0.06 0.13 0.26 -0.47 0.21
6030 || orf19.7293 || MPS1 || || Monopolar spindle protein, a putative kinase; essential for growth; periodic mRNA expression, peak at cell-cycle S/G2 phase || 1 0.17 -0.10 0.70 0.48 -0.32 -0.73 -0.01 0.32 0.08 0.22 0.45 0.19 0.12 0.24 -0.27 -0.03
6031 || orf19.612 || || || Ortholog of S. cerevisiae : AIM32, C. glabrata CBS138 : CAGL0L01529g, C. dubliniensis CD36 : Cd36_33550, C. parapsilosis CDC317 : CPAR2_702070 and Candida tenuis NRRL Y-1498 : CANTEDRAFT_114174 || 1 0.66 -0.01 0.86 0.85 -1.16 -0.73 0.35 0.44 0.34 0.20 0.34 -0.52 0.07 0.22 0.10 -0.20
6032 || orf19.3459 || || || Putative serine/threonine/tyrosine (dual-specificity) kinase; disruptants not obtained by UAU1 method || 1 0.58 0.27 0.24 0.36 -0.42 -0.61 -0.16 0.33 -0.13 -0.05 0.17 0.09 -0.13 -0.16 -0.46 0.23
6033 || orf19.3996 || || || Putative mannosyltransferase; similar to S. cerevisiae Gpi10p; has HKEXRF motif || 1 0.06 0.03 0.31 0.44 -0.63 -0.54 -0.23 0.03 0.12 -0.14 -0.34 0.24 -0.17 -0.21 -0.50 0.38
6034 || orf19.3490 || FGR6-4 || || Protein lacking an ortholog in S. cerevisiae; member of a family encoded by FGR6-related genes in the RB2 repeat sequence; transposon mutation affects filamentous growth || 1 0.25 0.06 0.31 0.33 -0.36 -0.52 -0.20 0.10 0.17 -0.06 -0.17 -0.06 -0.04 -0.05 -0.44 0.23
6035 || orf19.2443 || RGD1 || || GTPase activator protein; transcript induced in low iron; alkaline upregulated; localized to the bud emergence area in G1 phase and in the bud tip during S and G2 phases || 1 0.19 0.04 0.63 0.39 -0.44 -0.43 -0.06 0.13 0.17 -0.13 -0.11 0.16 0.00 -0.22 -0.61 0.15
6036 || orf19.727 || || || Predicted ORF overlapping the Major Repeat Sequence on chromosome R; member of a family encoded by FGR6-related genes in the RB2 repeat sequence || 1 0.15 -0.01 0.73 0.44 -0.37 -0.65 -0.17 0.33 0.12 0.09 -0.24 0.13 -0.23 -0.10 -0.37 0.56
6037 || orf19.1208 || || || Predicted ORF in the Major Repeat Sequence on chromosome 4; member of a family encoded by FGR6-related genes in the RB2 repeat sequence || 1 0.06 0.11 0.48 0.45 -0.27 -0.40 -0.29 0.11 0.03 0.09 -0.16 0.04 -0.08 -0.14 -0.33 0.50
6038 || orf19.4712 || FGR6-3 || || Protein lacking an ortholog in S. cerevisiae; member of a family encoded by FGR6-related genes in the RB2 repeat sequence; transposon mutation affects filamentous growth || 1 0.23 0.13 0.51 0.41 -0.21 -0.39 -0.29 0.18 0.25 0.05 -0.16 0.08 -0.10 -0.20 -0.19 0.33
6039 || orf19.1234 || FGR6-10 || || Protein lacking an ortholog in S. cerevisiae; member of a family encoded by FGR6-related genes in the RB2 repeat sequence; transposon mutation affects filamentous growth || 1 0.17 -0.03 0.48 0.50 -0.05 -0.44 -0.19 0.25 0.22 -0.22 -0.13 -0.03 0.13 -0.15 -0.42 0.22
6040 || orf19.993 || || || Protein of unknown function; rat catheter biofilm repressed || 1 -0.17 0.21 0.35 0.47 -0.11 -0.64 -0.11 0.16 0.47 0.08 0.09 0.13 0.07 -0.24 -0.31 0.37
6041 || orf19.6630 || || || Ortholog(s) have role in ER-associated ubiquitin-dependent protein catabolic process || 1 0.06 0.05 0.17 0.55 -0.34 -0.69 -0.17 0.16 0.19 0.10 0.00 0.10 -0.30 -0.62 -0.32 -0.12
6042 || orf19.1221 || ALG2 || || Putative mannosyltransferase involved in cell wall mannan biosynthesis; transcription is elevated in chk1, nik1, and sln1 homozygous null mutants || 1 0.05 0.01 0.15 0.46 -0.77 -0.67 -0.13 0.12 0.42 0.54 -0.06 -0.05 -0.31 -0.27 -0.30 -0.92
6043 || orf19.3518 || || || Ortholog(s) have dicarboxylic acid transmembrane transporter activity, role in mitochondrial transport and mitochondrial inner membrane localization || 1 0.03 -0.23 0.33 0.36 -0.47 -0.26 0.14 0.41 0.41 0.60 -0.52 -0.46 -0.51 -0.39 -0.15 -1.30
6044 || orf19.843 || || || Putative DNA repair exonuclease; fungal-specific (no human or murine homolog) || 1 0.03 -0.01 0.24 0.14 -0.00 -0.38 -0.05 0.03 0.32 0.12 -0.44 -0.13 -0.27 -0.18 -0.20 -0.49
6045 || orf19.1873 || || || Protein of unknown function; Hap43-repressed gene; repressed by nitric oxide || 1 0.55 0.50 -0.07 0.18 -0.22 -0.53 0.65 0.80 0.17 0.35 -0.34 -0.90 -0.43 -0.79 -0.55 -1.22
6046 || orf19.1873 || || || Protein of unknown function; Hap43-repressed gene; repressed by nitric oxide || 1 0.56 0.45 -0.04 0.08 -0.40 -0.65 0.56 0.92 0.36 0.41 -0.35 -0.48 -0.51 -0.79 -0.52 -0.88
6047 || orf19.7590 || || || Putative NADH-ubiquinone oxidoreductase; identified in detergent-resistant membrane fraction (possible lipid raft component); predicted N-terminal acetylation; repressed by nitric oxide || 1 0.63 0.61 -0.10 -0.32 -0.53 -0.48 0.56 0.58 -0.01 0.63 -0.39 -0.51 -0.44 -0.11 -0.61
6048 || orf19.7590 || || || Putative NADH-ubiquinone oxidoreductase; identified in detergent-resistant membrane fraction (possible lipid raft component); predicted N-terminal acetylation; repressed by nitric oxide || 1 0.25 0.32 -0.16 -0.26 -0.88 -0.44 0.20 0.35 0.31 0.72 -0.56 -0.42 -0.49 -0.82 -0.28 -0.55
6049 || orf19.1836 || APN2 || || Putative class II abasic (AP) endonuclease; flucytosine induced || 1 0.64 0.35 0.06 0.28 -0.80 -0.24 0.50 0.44 0.77 0.84 -0.67 0.18 0.28 0.04 -0.50 -0.75
6050 || orf19.7118 || || || Ortholog(s) have adenylate kinase activity, nucleoside triphosphate adenylate kinase activity, role in nucleotide metabolic process and mitochondrial inner membrane localization || 1 0.12 0.12 0.11 0.03 -0.54 -0.40 0.29 0.40 0.61 0.63 -0.45 -0.29 0.26 -0.08 -0.13 -0.70
6051 || orf19.6531 || NUC2 || || Putative NADH-ubiquinone oxidoreductase; identified in detergent-resistant membrane fraction (possible lipid raft component); alkaline repressed; Hap43-repressed; Spider biofilm repressed || 1 0.23 0.20 0.01 -0.11 -0.59 -0.44 0.32 0.35 0.51 0.79 -0.62 -0.31 -0.37 -0.05 -0.27 -0.50
6052 || orf19.7009 || || || Has domain(s) with predicted catalytic activity, coenzyme binding activity and role in cellular metabolic process || 1 -0.32 -0.15 -0.59 -0.12 -0.82 -0.68 0.63 0.19 1.11 0.39 -0.73 -0.91 -0.18 0.02 -1.18 -0.32
6053 || orf19.4653 || || || Protein similar to GPI-linked cell-wall proteins; induced in low iron; Spider biofilm induced; regulated in Spider biofilms by Bcr1, Tec1, Ndt80, Brg1 || 1 0.04 -0.12 0.59 1.04 -0.94 -0.76 1.11 0.87 1.35 -0.15 -0.87 -0.72 -0.97 0.10 -1.54 -0.65
6054 || orf19.4653 || || || Protein similar to GPI-linked cell-wall proteins; induced in low iron; Spider biofilm induced; regulated in Spider biofilms by Bcr1, Tec1, Ndt80, Brg1 || 1 -0.17 0.11 0.27 0.56 -1.02 -0.77 0.88 0.76 1.26 0.34 -0.87 -0.86 -0.72 -0.40 -0.92 -1.56
6055 || orf19.873.1 || COX6 || || Putative cytochrome c oxidase; flucytosine induced || 1 -0.17 -0.09 0.01 -0.14 -0.44 -0.29 0.35 0.41 0.66 0.42 -0.62 -0.55 -0.41 -0.24 -0.97 -0.83
6056 || orf19.873.1 || COX6 || || Putative cytochrome c oxidase; flucytosine induced || 1 0.16 0.00 0.27 -0.13 -0.53 -0.44 0.33 0.43 0.58 0.22 -0.78 -0.55 -0.50 -0.19 -1.13 -1.11
6057 || orf19.873.1 || COX6 || || Putative cytochrome c oxidase; flucytosine induced || 1 0.24 0.06 -0.07 -0.30 -0.33 -0.10 0.63 0.44 0.47 0.39 -0.59 -0.42 -0.18 -0.09 -0.95 -0.50
6058 || orf19.873.1 || COX6 || || Putative cytochrome c oxidase; flucytosine induced || 1 0.22 0.07 0.14 -0.27 -0.65 -0.35 0.62 0.70 0.73 0.53 -0.50 -0.48 -0.17 0.13 -1.02 -0.51
6059 || orf19.5213.1 || COX8 || || Putative cytochrome c oxidase; flucytosine induced; caspofungin repressed || 1 0.23 0.18 -0.18 -0.24 -0.83 -0.48 0.55 0.61 0.32 -0.19 -0.51 -0.44 -0.11 -0.20 -0.54 -0.46
6060 || orf19.5213.1 || COX8 || || Putative cytochrome c oxidase; flucytosine induced; caspofungin repressed || 1 0.35 0.20 -0.09 -0.14 -0.64 -0.37 0.57 0.53 0.41 -0.10 -0.44 -0.54 0.07 -0.13 -0.30 -0.34
6061 || orf19.1467 || COX13 || || Cytochrome c oxidase; flucytosine induced; repressed by nitric oxide || 1 0.37 0.35 0.25 0.09 -0.59 -0.33 0.41 0.53 0.35 -0.22 -0.47 -0.56 -0.02 0.35 -0.46 -0.54
6062 || orf19.2016 || ERG28 || || Ortholog(s) have protein binding, bridging activity, role in ergosterol biosynthetic process and endoplasmic reticulum membrane localization || 1 0.80 -0.31 0.41 0.24 -0.94 -0.60 0.41 0.37 0.75 -0.01 -0.19 -0.50 -0.01 -0.23 -0.85 -0.48
6063 || orf19.6086 || LEU4 || || Putative 2-isopropylmalate synthase; regulated by Nrg1, Mig1, Tup1, Gcn4; induced by human whole blood or PMNs; macrophage/pseudohyphal-repressed after 16h; Spider biofilm repressed || 1 0.24 -0.46 0.43 0.32 -1.18 -0.67 0.68 0.72 0.98 0.15 -0.33 -0.55 0.54 -0.18 -0.17 -0.44
6064 || orf19.2905 || || || Ortholog of Candida albicans WO-1 : CAWG_03194 || 1 0.91 -0.26 0.01 0.54 -0.37 -0.44 0.64 0.03 0.89 0.46 -0.57 -0.68 0.05 -0.35 -0.22 -0.61
6065 || orf19.732 || || || Possible dehydrogenase; flow model biofilm induced; rat catheter biofilm induced; Spider biofilm induced || 1 -0.08 0.05 0.20 -0.04 -0.22 -0.30 -0.01 0.06 0.25 -0.24 -0.28 -0.67 -0.45 -0.12 -0.36 -0.18
6066 || orf19.781 || DUR31 || || High affinity spermidine transporter; expression is induced by urea; fungal-specific (no human or murine homolog); not required for virulence in a mouse intravenous model || 1 -0.03 0.17 0.22 0.12 -0.19 -0.40 0.22 -0.00 0.50 0.02 -0.71 -0.87 -0.49 -0.36 0.21 -0.53
6067 || orf19.3134 || || || Protein of unknown function; flow model biofilm induced || 1 0.50 0.81 0.51 0.67 0.16 -0.86 -0.11 0.20 1.14 0.28 -0.99 -2.38 -0.27 -0.09 -0.42 -0.15
6068 || orf19.4804 || LIP2 || || Secreted lipase; member of a differentially expressed lipase gene family; expressed in alimentary tract, but not oral tissue, during mouse oral infection; may have a role in nutrition and/or in creating an acidic microenvironment || 1 0.41 0.76 0.25 1.24 -0.24 -0.14 -0.05 -0.41 0.07 -0.53 -1.86 -0.54 -0.43 -0.54 -0.07
6069 || orf19.2117 || LEU5 || || Putative mitochondrial carrier protein; Hap43-repressed; rat catheter biofilm induced || 1 -0.14 0.59 0.17 0.77 -0.01 -0.02 -0.27 -0.53 0.36 0.15 -0.79 -0.25 0.24 -0.54 -0.08 -0.85
6070 || orf19.6998 || GTT1 || || Putative glutathione S-transferase; downregulated upon adherence to polystyrene; regulated upon white-opaque switching; induced in the presence of human neutrophils; oxidative stress-induced via Cap1p; regulated by Gcn2p, Gcn4p || 1 1.95 2.16 1.11 2.57 -0.10 -0.80 -0.06 -0.18 0.20 0.84 -0.23 -1.38 -0.05 -3.25 -0.53 -2.89
6071 || orf19.3468 || ALG11 || || Alpha-1,2-mannosyltransferase; catalyzes sequential addition of 2 terminal alpha 1,2-mannose residues to the Man5GlcNAc2-PP-dolichol intermediate during asparagine-linked glycosylation in the ER; Spider biofilm induced || 1 0.21 0.37 0.61 0.64 0.01 -0.49 -0.40 -0.09 0.02 0.69 -0.15 -0.44 0.33 -0.86 -0.41 -1.20
6072 || orf19.1327 || RBT1 || || Cell wall protein with similarity to Hwp1; required for virulence; predicted glycosylation; fluconazole, Tup1 repressed; farnesol, alpha factor, serum, hyphal and alkaline induced; Rfg1, Rim101-regulated || 1 0.49 0.63 0.46 0.49 -0.83 -1.33 -0.27 -0.65 1.04 0.59 -1.38 -0.71 -0.02 -1.49 -1.15 -2.18
6073 || orf19.929 || || || Protein of unknown function; rat catheter biofilm repressed || 1 0.24 0.26 0.16 0.43 -0.49 -0.66 0.18 0.17 0.79 0.88 -1.02 -1.11 -0.39 -1.03 -0.65 -1.53
6074 || orf19.6302 || PGA39 || || Putative GPI-anchored protein || 1 1.66 0.81 0.07 1.09 -0.46 -0.87 0.27 -0.53 0.43 1.00 -0.51 -2.56 -0.23 -1.59 -0.41 -2.28
6075 || orf19.6028 || HGC1 || || Hypha-specific G1 cyclin-related protein involved in regulation of morphogenesis, biofilm formation; Cdc28-Hgc1 maintains Cdc11 S394 phosphorylation during hyphal growth; required for virulence in mice; regulated by Nrg1, Tup1, farnesol || 1 1.35 0.81 0.13 0.70 -0.71 -1.13 0.56 0.32 0.56 1.47 -0.49 -1.90 -0.14 -2.10 -0.84 -1.91
6076 || orf19.929 || || || Protein of unknown function; rat catheter biofilm repressed || 1 1.12 0.25 0.64 0.65 -0.72 -0.15 0.56 0.07 1.30 1.09 -0.50 -1.01 -0.43 -1.14 -0.51 -1.44
6077 || orf19.3829 || PHR1 || || Cell surface glycosidase; may act on cell-wall beta-1,3-glucan prior to beta-1,6-glucan linkage; role in systemic, not vaginal virulence (neutral, not low pH); high pH or filamentation induced; Bcr1-repressed in RPMI a/a biofilm || 1 0.17 0.31 0.61 0.67 0.07 0.01 -0.12 -0.11 0.60 1.00 -0.79 -0.87 -0.04 -0.55 -0.20 -0.79
6078 || orf19.3829 || PHR1 || || Cell surface glycosidase; may act on cell-wall beta-1,3-glucan prior to beta-1,6-glucan linkage; role in systemic, not vaginal virulence (neutral, not low pH); high pH or filamentation induced; Bcr1-repressed in RPMI a/a biofilm || 1 0.18 0.61 0.54 0.76 -0.13 -0.36 0.07 -0.24 0.71 0.98 -0.78 -1.30 0.37 -0.52 -0.34 -1.33
6079 || orf19.4063 || GPT1 || || GABA/polyamine transporter; 9 to 11 membrane spanning segments; complements GABA uptake defect of an S. cerevisiae uga4 put4 gap1 triple mutant; complements growth of an S. cerevisiae spe1 mutant under polyamine limitation || 1 0.03 0.21 0.27 0.92 -0.25 -0.66 0.29 -0.05 1.13 0.95 -0.63 -1.60 0.41 -0.70 -0.47 -1.29
6080 || orf19.1822 || UME6 || || Zn(II)2Cys6 transcription factor; role in hyphal extension, virulence, adherence to plastic; filament induced; regulated by Nrg1/Tup1/Rfg1, alkaline conditions; expression promotes highly filamentous biofilms; rat catheter biofilm induced || 1 0.96 0.83 0.72 0.90 0.07 -0.91 0.33 0.46 1.03 1.43 -0.59 -1.60 0.46 -1.10 -0.23 -0.64
6081 || orf19.6420 || PGA13 || || GPI-anchored cell wall protein involved in cell wall synthesis; required for normal cell surface properties; induced in oralpharyngeal candidasis; Spider biofilm induced; Bcr1-repressed in RPMI a/a biofilms || 1 0.58 0.22 0.83 1.00 -0.39 -0.64 0.29 -0.42 0.44 0.48 -1.88 -1.51 0.09 -1.78 -1.28 -0.86
6082 || orf19.4583 || || || Protein with a mitochondrial carrier protein domain; possibly an essential gene, disruptants not obtained by UAU1 method; Spider biofilm repressed || 1 0.03 0.08 0.44 0.29 -0.16 -0.65 0.17 -0.25 0.17 0.11 -0.58 -0.25 -0.10 -0.77 -0.39 -0.26
6083 || orf19.6178 || FBP1 || || Fructose-1,6-bisphosphatase; key gluconeogenesis enzyme; regulated by Efg1, Ssn6; induced by phagocytosis; effects switch from glycolysis to gluconeogenesis in macrophage; rat flow model biofilm induced; overlaps orf19.6179 || 1 0.03 0.17 0.64 0.42 0.05 -0.30 -0.05 0.02 0.57 0.21 -0.52 -0.26 0.08 -0.09 -0.05 -0.46
6084 || orf19.1985 || || || Has aminoglycoside phosphotransferase and protein kinase domains; rat catheter and flow model biofilm induced || 1 0.12 0.23 0.96 0.65 -0.23 -0.14 -0.02 0.07 0.82 0.39 -0.64 -0.17 0.03 -0.08 -0.52 -0.70
6085 || orf19.6156 || || || Ortholog of S. cerevisiae : AIM11, C. glabrata CBS138 : CAGL0I04928g, C. dubliniensis CD36 : Cd36_80770, C. parapsilosis CDC317 : CPAR2_102260 and Candida tenuis NRRL Y-1498 : CANTEDRAFT_114262 || 1 0.14 0.17 0.75 0.12 0.14 -0.03 -0.00 0.06 0.33 0.49 -0.35 -0.36 0.17 -0.38 -0.44 -0.65
6086 || orf19.7222 || PAM16 || || Putative maltase; regulated by Gcn4; repressed by amino acid starvation (3-AT); rat catheter biofilm induced || 1 -0.20 -0.06 0.44 0.09 -0.03 -0.14 -0.29 -0.14 0.26 0.44 -0.21 -0.16 0.17 -0.39 -0.24 -0.86
6087 || orf19.5874 || || || Ortholog of C. dubliniensis CD36 : Cd36_84250, C. parapsilosis CDC317 : CPAR2_806160, Candida tenuis NRRL Y-1498 : CANTEDRAFT_137075 and Debaryomyces hansenii CBS767 : DEHA2F11462g || 1 -0.15 -0.33 0.85 0.16 -0.03 -0.10 -0.23 -0.17 0.53 0.30 -0.53 -0.08 0.13 -0.34 -0.58
6088 || orf19.7167 || || || Putative adhesin-like protein || 1 -0.17 -0.22 0.67 0.32 -0.78 0.23 -0.77 -0.43 0.15 0.19 -0.82 -1.69 -0.28 0.48 -0.97 -0.65
6089 || orf19.7320 || LIP7 || || Probable lipase, part of a gene family whose members are differentially expressed during infection; lacks a signal sequence for secretion, unlike other family members; may have a role in nutrition or in creating an acidic microenvironment || 1 -0.32 0.29 -0.30 0.80 -0.25 -0.06 -0.78 -0.98 0.12 0.18 -1.44 -1.77 -0.89 -0.09 -0.66 -0.47
6090 || orf19.4839 || || || GET complex subunit; expression downregulated in an ssr1 null mutant || 1 -0.30 -0.33 0.02 0.07 -0.14 -0.17 -0.04 -0.14 -0.12 -0.21 -0.34 -0.30 -0.03 -0.33 -0.06 -0.47
6091 || orf19.2695 || UBR1 || || Protein similar to S. cerevisiae Ubr1p ubiquitin-protein ligase; transposon mutation affects filamentous growth; Spider biofilm induced || 1 -0.13 -0.50 -0.25 -0.16 -0.13 -0.38 -0.01 -0.06 -0.05 -0.24 -0.44 -0.49 -0.29 -0.25 -0.11 -0.82
6092 || orf19.1913 || || || Protein of unknown function; flow model biofilm induced || 1 -0.32 -0.22 0.02 -0.20 -0.25 -0.34 -0.32 -0.06 -0.19 -0.17 -0.20 -0.38 0.14 -0.01 -0.14 -0.92
6093 || orf19.3242 || || || Putative TFIID and SAGA complex subunit; possibly an essential gene, disruptants not obtained by UAU1 method || 1 0.04 0.09 -0.59 -0.46 0.04 -0.72 -0.30 -0.06 -0.66 -0.21 -0.43 -0.63 -0.09 -0.38 -0.20 -0.81
6094 || orf19.3134 || || || Protein of unknown function; flow model biofilm induced || 1 0.50 0.09 -0.55 -0.52 -0.81 0.29 0.18 -0.87 -1.07 -1.38 -0.20 -0.55 -0.29 -1.95
6095 || orf19.1467 || COX13 || || Cytochrome c oxidase; flucytosine induced; repressed by nitric oxide || 1 0.28 0.24 -0.43 -0.65 -0.62 -0.88 0.36 0.32 -0.40 -1.00 -0.57 -1.22 -0.22 -0.56 -0.70 -1.04
6096 || orf19.5526 || SEC20 || || Essential protein; similar to S. cerevisiae Sec20p; depletion causes membrane accumulation and drug sensitivity; expression regulated by growth phase; O-mannosylation regulates proteolysis; does not complement S. cerevisiae sec20-1 mutant || 1 0.17 0.10 0.17 -0.48 -0.56 -0.53 -0.29 0.04 -0.20 -0.45 -0.37 -0.26 -0.12 -0.79 -0.89 -0.65
6097 || orf19.6921 || || || Ortholog(s) have RNA polymerase I upstream control element sequence-specific DNA binding transcription factor activity and role in chromatin organization, transcription of nuclear large rRNA transcript from RNA polymerase I promoter || 1 0.09 0.17 -0.03 -0.12 -0.42 -0.30 -0.28 -0.38 -0.44 -0.13 -0.11 -0.17 0.14 -0.12 -0.74 -0.85
6098 || orf19.829 || SCH9 || || Protein kinase; involved in growth control, cell size, resistance to rapamycin, cations, chlamydospore formation, filamentous growth under some conditions, and virulence; prevents hyphal growth in hypoxia at high CO2; Spider biofilm induced || 1 0.16 0.04 0.04 0.16 -0.55 -0.20 -0.15 -0.43 -0.54 -0.14 -0.28 -0.42 0.12 0.13 -0.83 -0.57
6099 || orf19.192 || || || Ortholog of C. dubliniensis CD36 : Cd36_19320, C. parapsilosis CDC317 : CPAR2_209670, Candida tenuis NRRL Y-1498 : CANTEDRAFT_113478 and Debaryomyces hansenii CBS767 : DEHA2C15136g || 1 -0.20 0.02 0.12 -0.04 -0.26 -0.78 -0.86 -0.73 -0.42 -0.43 -0.59 -0.59 -0.52 0.50 -0.64 -0.38
6100 || orf19.192 || || || Ortholog of C. dubliniensis CD36 : Cd36_19320, C. parapsilosis CDC317 : CPAR2_209670, Candida tenuis NRRL Y-1498 : CANTEDRAFT_113478 and Debaryomyces hansenii CBS767 : DEHA2C15136g || 1 0.21 -0.04 -0.29 -0.37 -0.38 -1.20 -0.89 -0.78 -0.95 -0.64 -0.65 -0.58 -0.62 0.22 -0.77 -0.63
6101 || orf19.5754 || || || Putative membrane protein with a predicted role in zinc ion homeostasis; Hap43-induced; fluconazole-induced; rat catheter and Spider biofilm induced || 1 -0.01 0.00 -0.23 -0.47 -0.58 -1.04 -0.61 -0.42 -1.37 -1.12 -0.69 -1.31 -0.47 0.10 -1.36 -0.78
6102 || orf19.1930 || CFL5 || || Ferric reductase; induced in low iron; ciclopirox olamine, flucytosine induced; amphotericin B, Sfu1 repressed; Tbf1, Hap43 induced || 1 0.92 0.85 -1.33 -0.49 -3.24 -6.90 -4.06 -2.96 -4.60 -2.82 -3.54 -7.04 1.23 2.02 -4.45 -3.10
6103 || orf19.1930 || CFL5 || || Ferric reductase; induced in low iron; ciclopirox olamine, flucytosine induced; amphotericin B, Sfu1 repressed; Tbf1, Hap43 induced || 1 0.75 0.58 -0.82 -0.43 -3.87 -4.53 -2.99 -3.09 -4.36 -3.24 -4.06 -4.61 1.21 2.14 -4.25 -2.93
6104 || orf19.1930 || CFL5 || || Ferric reductase; induced in low iron; ciclopirox olamine, flucytosine induced; amphotericin B, Sfu1 repressed; Tbf1, Hap43 induced || 1 1.18 0.87 -0.79 -0.04 -3.17 -4.15 -3.04 -2.44 -2.83 -3.66 -2.92 -4.58 1.11 2.14 -2.77 -1.88
6105 || orf19.1930 || CFL5 || || Ferric reductase; induced in low iron; ciclopirox olamine, flucytosine induced; amphotericin B, Sfu1 repressed; Tbf1, Hap43 induced || 1 0.73 0.78 -0.70 0.03 -2.56 -4.12 -2.80 -2.04 -2.19 -4.00 -2.90 -4.32 1.01 2.18 -3.18 -1.92
6106 || orf19.1930 || CFL5 || || Ferric reductase; induced in low iron; ciclopirox olamine, flucytosine induced; amphotericin B, Sfu1 repressed; Tbf1, Hap43 induced || 1 0.59 0.52 -0.12 0.28 -0.18 -1.33 -0.84 -1.07 -1.27 -2.55 -0.90 -2.21 0.86 2.21 -0.64 -0.99
6107 || orf19.339 || NDE1 || || Putative NADH dehydrogenase; may act alternatively to complex I in respiration; caspofungin repressed; rat catheter biofilm induced; Spider biofilm repressed || 1 0.66 0.45 0.69 0.38 -0.91 -0.41 -0.32 -0.30 -0.76 -1.33 -0.04 -0.99 0.61 1.03 -0.88 0.06
6108 || orf19.339 || NDE1 || || Putative NADH dehydrogenase; may act alternatively to complex I in respiration; caspofungin repressed; rat catheter biofilm induced; Spider biofilm repressed || 1 0.36 0.46 0.58 0.15 -0.97 -0.58 -0.42 -0.33 -0.85 -1.27 -0.02 -0.97 0.61 1.11 -1.32 -0.20
6109 || orf19.5267 || || || Putative cell wall adhesin-like protein; repressed in core caspofungin response and by alpha pheromone in SpiderM medium; transcript reduced in ace2 mutant; flow model, rat catheter and Spider biofilm repressed || 1 0.98 0.88 0.96 0.94 -1.42 -1.92 -0.72 -0.95 -1.58 -2.04 -0.48 -1.18 1.53 0.43 -1.29 -0.77
6110 || orf19.5267 || || || Putative cell wall adhesin-like protein; repressed in core caspofungin response and by alpha pheromone in SpiderM medium; transcript reduced in ace2 mutant; flow model, rat catheter and Spider biofilm repressed || 1 1.09 1.03 1.37 1.34 -1.75 -1.68 -0.85 -0.65 -1.01 -1.61 -1.06 -0.79 1.38 1.08 -1.27 -0.26
6111 || orf19.5267 || || || Putative cell wall adhesin-like protein; repressed in core caspofungin response and by alpha pheromone in SpiderM medium; transcript reduced in ace2 mutant; flow model, rat catheter and Spider biofilm repressed || 1 1.57 1.44 1.51 1.42 -4.18 -1.78 -0.67 -0.61 -1.17 -1.80 -0.68 -1.08 1.68 0.58 -1.91 -0.83
6112 || orf19.5267 || || || Putative cell wall adhesin-like protein; repressed in core caspofungin response and by alpha pheromone in SpiderM medium; transcript reduced in ace2 mutant; flow model, rat catheter and Spider biofilm repressed || 1 1.03 0.80 1.18 1.13 -3.89 -2.01 -0.78 -0.52 -1.06 -1.62 -0.92 -1.04 1.38 1.03 -1.84 -0.54
6113 || orf19.5267 || || || Putative cell wall adhesin-like protein; repressed in core caspofungin response and by alpha pheromone in SpiderM medium; transcript reduced in ace2 mutant; flow model, rat catheter and Spider biofilm repressed || 1 1.07 0.95 1.33 1.34 -4.96 -2.08 -1.02 -0.79 -1.44 -1.87 -1.46 -1.18 1.38 1.03 -2.40 -1.14
6114 || orf19.22 || || || Protein with homology to peroxisomal membrane proteins; Sef1p-, Sfu1p-, and Hap43p-regulated gene || 1 0.27 0.25 0.48 0.89 -1.44 -1.79 -0.33 -0.65 -1.17 -0.56 -0.18 -0.29 -0.15 1.07 -1.40 0.16
6115 || orf19.22 || || || Protein with homology to peroxisomal membrane proteins; Sef1p-, Sfu1p-, and Hap43p-regulated gene || 1 0.57 0.45 0.94 1.21 -1.44 -1.43 0.16 -0.15 -1.21 -0.55 -0.07 -0.11 0.06 1.00 -0.53 0.19
6116 || orf19.6591 || PCD1 || || Ortholog(s) have 8-oxo-7,8-dihydroguanosine triphosphate pyrophosphatase activity, role in DNA repair and peroxisome localization || 1 0.15 0.12 0.25 0.95 -0.71 -0.81 -0.23 -0.17 -0.50 -0.41 -0.05 -0.03 0.09 0.10 -0.43 -0.27
6117 || orf19.6791 || HHT1 || || Putative histone H3; reduced mRNA abundance in fkh2 mutant; farnesol regulated; Spider biofilm induced; rat catheter biofilm repressed || 1 0.21 0.12 0.16 0.54 -0.63 -0.63 -0.29 -0.28 -0.44 -0.67 -0.03 -0.30 0.35 -0.04 0.11 -0.17
6118 || orf19.1671 || UTR2 || || Putative GPI anchored cell wall glycosidase; role in adhesion, hyphal growth on Spider (not serum) medium; chitin-binding, glycosyl hydrolase domains; induced during cell wall regeneration; mRNA in yeast-form cells; Spider biofilm induced || 1 -0.04 -0.02 0.10 -0.02 -0.95 -0.76 0.61 0.31 0.30 -0.11 -1.15 -0.77 0.73 0.61 -0.01 -0.61
6119 || orf19.782 || || || Ortholog(s) have serine hydrolase activity, triglyceride lipase activity, role in lipid homeostasis and lipid particle localization || 1 0.31 0.16 0.13 0.07 -0.87 -0.69 0.47 0.20 0.24 -0.07 -0.87 -0.43 0.40 0.25 0.21 -0.49
6120 || orf19.5992 || WOR2 || || Zn(II)2Cys6 transcription factor; regulator of white-opaque switching; required for maintenance of opaque state; Hap43-induced || 1 0.61 0.63 0.81 0.81 -1.89 -1.00 0.57 -0.23 0.25 -0.17 -1.76 -0.60 1.72 0.57 -0.29 -1.81
6121 || orf19.5992 || WOR2 || || Zn(II)2Cys6 transcription factor; regulator of white-opaque switching; required for maintenance of opaque state; Hap43-induced || 1 0.74 0.74 0.70 0.70 -2.03 -1.00 0.79 -0.14 0.32 -0.26 -1.77 -0.72 1.83 0.61 -0.43 -1.49
6122 || orf19.5537 || WSC2 || || Putative cell wall integrity and stress response protein; mRNA binds She3; Spider biofilm induced || 1 0.22 -0.06 0.26 0.68 -1.24 -0.59 0.69 0.03 0.17 -0.01 -0.75 -0.55 1.37 0.81 0.20 -0.61
6123 || orf19.6556 || || || Protein of unknown function; rat catheter, flow model and Spider biofilm induced || 1 0.56 0.19 0.32 0.58 -1.65 -0.84 0.69 -1.30 -0.19 -0.41 -2.08 -1.77 1.71 0.93 -0.28 -2.35
6124 || orf19.6556 || || || Protein of unknown function; rat catheter, flow model and Spider biofilm induced || 1 0.25 -0.00 0.42 0.87 -2.52 -1.21 0.54 -1.76 -0.17 -0.46 -2.91 -2.21 1.59 0.71 -0.78 -3.46
6125 || orf19.4792 || || || Protein with a regulator of G-protein signaling domain; Plc1-regulated; Spider biofilm induced; rat catheter biofilm repressed || 1 0.19 0.15 0.28 0.27 -1.08 -0.45 0.42 -0.61 0.14 -0.03 -1.20 -0.83 0.23 0.56 -1.13 -0.58
6126 || orf19.4000 || GRF10 || || Putative homeodomain transcription factor; null mutant is an adenine auxotroph; Spider biofilm induced; promoter bound by Bcr1, Tec1, Efg1, Ndt80 and Brg1 || 1 0.63 0.51 0.42 0.47 -1.36 -0.80 1.02 -1.33 0.36 0.01 -1.97 -0.68 1.21 0.56 -1.73 -1.48
6127 || orf19.4000 || GRF10 || || Putative homeodomain transcription factor; null mutant is an adenine auxotroph; Spider biofilm induced; promoter bound by Bcr1, Tec1, Efg1, Ndt80 and Brg1 || 1 0.66 0.81 0.77 0.49 -0.70 -0.58 1.05 -0.81 0.61 0.29 -1.14 -0.73 1.29 0.55 -1.05 -1.67
6128 || orf19.2903 || AGO1 || || Putative Argonaute protein involved in RNA silencing; hyphal-induced expression; regulated by Cyr1, Ras1, Efg1, Nrg1, Tup1; rat catheter biofilm repressed || 1 0.31 0.28 0.09 0.09 -0.47 -0.49 0.05 -0.24 0.06 0.09 -1.10 -0.32 0.77 0.22 -0.50 -0.26
6129 || orf19.1186 || || || Has domain(s) with predicted role in attachment of GPI anchor to protein and GPI-anchor transamidase complex localization || 1 0.67 0.69 0.52 0.45 -1.03 -1.50 -0.35 0.19 0.08 0.62 -0.48 -0.60 -0.34 0.17 -0.39 -0.63
6130 || orf19.6254 || ANT1 || || Peroxisomal adenine nucleotide transporter; role in beta-oxidation of medium-chain fatty acid and peroxisome proliferation; rat catheter biofilm induced || 1 1.12 0.93 0.79 1.34 -1.65 -2.17 -0.47 -0.01 0.08 0.79 -1.31 -1.09 -0.64 0.26 -1.05 -0.95
6131 || orf19.2936 || || || Ortholog of C. parapsilosis CDC317 : CPAR2_106450, C. dubliniensis CD36 : Cd36_02330, Lodderomyces elongisporus NRLL YB-4239 : LELG_01618 and Candida orthopsilosis Co 90-125 : CORT_0B07690 || 1 0.54 0.63 0.49 0.88 -1.33 -1.96 0.14 0.84 0.33 0.86 -1.32 -0.98 -0.48 0.08 -0.66 -1.50
6132 || orf19.899 || || || Ortholog of C. dubliniensis CD36 : Cd36_18040, C. parapsilosis CDC317 : CPAR2_211790, Candida tenuis NRRL Y-1498 : CANTEDRAFT_109928 and Debaryomyces hansenii CBS767 : DEHA2E21010g || 1 1.31 1.29 0.77 1.12 -1.54 -2.12 0.31 0.80 0.11 0.66 -1.62 -0.92 -0.45 -0.04 -1.49 -1.32
6133 || orf19.899 || || || Ortholog of C. dubliniensis CD36 : Cd36_18040, C. parapsilosis CDC317 : CPAR2_211790, Candida tenuis NRRL Y-1498 : CANTEDRAFT_109928 and Debaryomyces hansenii CBS767 : DEHA2E21010g || 1 1.23 1.35 0.96 1.13 -1.06 -1.84 0.24 0.90 0.22 0.80 -1.32 -1.18 -0.23 -0.36 -1.59 -1.44
6134 || orf19.1721 || NCE103 || || Carbonic anhydrase; converts of CO2 to bicarbonate; essential for virulence in host niches with limited CO2, normal white-opaque switch; Mnl1-induced in weak acid stress; Hap43-induced gene; F-12/CO2, rat catheter, Spider biofilm induced || 1 1.48 1.39 0.59 0.96 -1.77 -2.09 -0.49 -0.21 -0.12 1.26 -1.44 -2.21 -1.10 0.23 -2.32 -1.71
6135 || orf19.1037 || || || Protein of unknown function; rat catheter biofilm repressed || 1 0.84 0.81 0.14 0.87 -1.15 -1.28 0.25 0.00 0.41 -0.14 -1.59 -1.53 0.02 0.61 -1.72 -0.83
6136 || orf19.935 || AGA1 || || Protein with some similarity to agglutinin subunit; expression regulated upon white-opaque switch; Spider biofilm induced || 1 0.92 0.91 1.17 2.29 -3.53 -0.78 -1.04 0.19 0.60 -3.61 -2.90 0.41 -1.54 -3.00 -1.82
6137 || orf19.935 || AGA1 || || Protein with some similarity to agglutinin subunit; expression regulated upon white-opaque switch; Spider biofilm induced || 1 1.50 1.45 1.27 2.40 -2.43 -3.10 0.17 -0.49 0.84 0.83 -2.73 -1.92 0.85 -1.47 -2.09 -1.38
6138 || orf19.4459 || || || Predicted heme-binding stress-related protein; Tn mutation affects filamentous growth; induced during chlamydospore formation in C. albicans and C. dubliniensis; Spider biofilm induced || 1 2.34 2.13 1.70 1.25 -3.79 -4.09 0.23 -0.74 0.79 0.61 -3.88 -3.62 0.15 -0.63 -3.51 -3.31
6139 || orf19.4459 || || || Predicted heme-binding stress-related protein; Tn mutation affects filamentous growth; induced during chlamydospore formation in C. albicans and C. dubliniensis; Spider biofilm induced || 1 2.49 2.47 1.79 1.31 -4.49 -4.26 0.35 -0.80 1.02 0.74 -4.46 -3.33 0.42 -0.22 -3.59 -3.00
6140 || orf19.4459 || || || Predicted heme-binding stress-related protein; Tn mutation affects filamentous growth; induced during chlamydospore formation in C. albicans and C. dubliniensis; Spider biofilm induced || 1 2.42 2.33 1.84 1.21 -4.86 -4.32 0.19 -0.73 0.85 0.61 -4.64 -3.23 0.21 -0.42 -4.20 -3.20
6141 || orf19.4459 || || || Predicted heme-binding stress-related protein; Tn mutation affects filamentous growth; induced during chlamydospore formation in C. albicans and C. dubliniensis; Spider biofilm induced || 1 2.25 2.03 1.81 1.44 -4.26 -3.45 0.13 -0.89 0.78 0.63 -4.11 -3.22 0.15 -0.13 -3.74 -3.23
6142 || orf19.4459 || || || Predicted heme-binding stress-related protein; Tn mutation affects filamentous growth; induced during chlamydospore formation in C. albicans and C. dubliniensis; Spider biofilm induced || 1 3.07 2.67 2.62 2.08 -4.62 -2.87 0.51 -0.59 0.74 0.57 -4.65 -2.54 0.61 -0.62 -3.91 -2.80
6143 || orf19.3156 || || || Protein of unknown function; induced by Mnl1 under weak acid stress || 1 1.80 1.84 -1.37 -0.83 -0.55 -0.43 0.45 0.71 -1.78 -2.03 0.92 -0.18 -1.44 -1.55
6144 || orf19.5760 || IHD1 || || GPI-anchored protein; alkaline, hypha-induced; regulated by Nrg1, Rfg1, Tup1 and Tsa1, Tsa1B in minimal media at 37; oralpharyngeal candidasis induced ; Spider biofilm induced; regulated in Spider biofilms by Tec1, Efg1, Ndt80, Rob1, Brg1 || 1 1.98 1.93 -2.33 -2.14 -0.38 -0.38 0.35 0.73 -2.90 -2.99 1.24 -0.10 -2.47 -2.54
6145 || orf19.575 || HYR3 || || Putative GPI-anchored adhesin-like protein; similar to Hyr1p induced in high iron; clade-specific repeat variation || 1 2.00 -1.75 -1.86 -0.04 -0.07 0.47 0.72 -2.43 -2.52 1.16 -0.23 -1.55 -2.49
6146 || orf19.5730 || || || Putative phenylacrylic acid decarboxylase; clade-associated gene expression || 1 2.20 1.97 0.56 0.69 -1.50 -1.47 -0.23 -0.31 -0.39 0.01 -2.86 -2.34 1.62 -0.69 -1.77 -2.43
6147 || orf19.575 || HYR3 || || Putative GPI-anchored adhesin-like protein; similar to Hyr1p induced in high iron; clade-specific repeat variation || 1 1.69 1.19 0.09 0.46 -1.46 -0.93 -0.34 -0.44 0.08 -0.53 -2.13 -1.45 0.79 -0.64 -1.50 -1.45
6148 || orf19.182 || || || Ortholog(s) have rRNA (guanine-N1-)-methyltransferase activity, role in rRNA modification and endoplasmic reticulum, mitochondrion localization || 1 1.27 1.36 0.77 0.92 -1.64 -1.72 -0.32 -0.38 -0.44 0.23 -2.35 -1.88 1.02 -0.24 -2.04 -3.17
6149 || orf19.6192 || || || Protein of unknown function; Plc1-regulated; transcript detected in high-resolution tiling arrays || 1 1.41 1.58 1.58 1.65 -3.39 0.02 0.05 0.68 0.69 -1.74 -1.40 1.01 0.04 -2.06 -3.16
6150 || orf19.2462 || PRN3 || || Protein similar to pirin; induced by Mnl1 under weak acid stress; Hap43-repressed; Spider biofilm induced || 1 1.18 0.93 0.94 0.62 -1.29 -0.68 -0.01 -0.28 0.35 0.54 -1.08 -1.86 -0.17 0.54 -1.59 -0.74
6151 || orf19.3535 || || || Ortholog(s) have cellular bud neck, fungal-type vacuole localization || 1 0.71 0.66 0.28 0.19 -0.80 -0.80 -0.27 0.08 -0.43 0.18 -0.60 -0.75 0.49 0.34 -0.89 -0.76
6152 || orf19.1842 || BUD5 || || Predicted GTP/GDP exchange factor for Rsr1; rat catheter biofilm induced || 1 0.63 0.53 0.63 0.45 -0.92 -1.36 -0.00 -0.34 -0.24 0.00 -0.65 -0.30 0.67 0.58 -0.81 -0.68
6153 || orf19.1490 || MSB2 || || Mucin family adhesin-like protein; cell wall damage sensor; required for Cek1 phosphorylation by cell wall stress; Rim101-repressed; activation releases extracellular domain into medium; Spider biofilm induced || 1 0.27 0.14 0.23 0.42 -1.03 -1.41 -0.04 -0.04 -0.02 0.29 -0.51 -0.58 0.54 0.19 -0.96 -0.87
6154 || orf19.4792 || || || Protein with a regulator of G-protein signaling domain; Plc1-regulated; Spider biofilm induced; rat catheter biofilm repressed || 1 -0.08 -0.02 0.09 0.14 -1.12 -0.96 0.56 -0.53 -0.20 -0.41 -0.82 -1.15 0.33 0.65 -0.97 -0.66
6155 || orf19.3337 || || || Protein of unknown function; merged with orf19.3338; rat catheter, flow and Spider model biofilm induced; promoter bound by Bcr1, Efg1, Ndt80, and Rob1; orf19.3338 Bcr1-repressed in RPMI a/a biofilms || 1 -0.44 -0.55 -0.15 0.44 -3.92 -5.01 3.26 -0.88 0.39 -1.18 -3.71 -3.05 1.68 1.67 -3.56 -3.63
6156 || orf19.3338 || || || Protein of unknown function; Bcr1-repressed in RPMI a/a biofilms; rat catheter and Spider biofilm induced; ORF deleted and merged with orf19.3337 || 1 -0.65 -0.54 -0.49 -0.29 -4.85 -5.74 2.45 -1.44 0.97 -0.59 -4.99 -5.20 0.83 1.96 -4.17 -3.61
6157 || orf19.3338 || || || Protein of unknown function; Bcr1-repressed in RPMI a/a biofilms; rat catheter and Spider biofilm induced; ORF deleted and merged with orf19.3337 || 1 -0.63 -0.53 -0.56 -0.56 -3.04 -2.98 2.55 -1.25 0.95 -0.79 -4.10 -3.45 1.08 1.90 -3.16 -4.25
6158 || orf19.3337 || || || Protein of unknown function; merged with orf19.3338; rat catheter, flow and Spider model biofilm induced; promoter bound by Bcr1, Efg1, Ndt80, and Rob1; orf19.3338 Bcr1-repressed in RPMI a/a biofilms || 1 -0.58 -0.83 -0.48 -0.04 -3.32 -2.57 3.13 -1.15 0.32 -1.43 -4.97 -4.55 1.32 2.07 -4.26 -5.24
6159 || orf19.5735.3 || || || Protein of unknown function; Spider biofilm induced || 1 -0.11 0.09 -0.44 -1.58 -3.67 -4.94 0.57 -0.46 -1.68 -1.72 -5.69 -6.53 3.09 2.20 -3.54 -5.61
6160 || orf19.5735.3 || || || Protein of unknown function; Spider biofilm induced || 1 -0.29 -0.01 -0.26 -1.18 -3.30 -4.40 -0.06 -1.03 -1.80 -1.66 -3.70 -4.84 2.51 2.07 -3.24 -4.45
6161 || orf19.4599 || PHO89 || || Putative phosphate permease; transcript regulated upon white-opaque switch; alkaline induced by Rim101; possibly adherence-induced; F-12/CO2 model, rat catheter and Spider biofilm induced || 1 0.82 0.68 1.54 1.02 -1.62 -1.98 -0.89 -0.62 -1.40 -0.40 -2.05 -3.38 1.70 1.14 -1.58 -2.34
6162 || orf19.5392 || NGT1 || || N-acetylglucosamine (GlcNAc)-specific transporter; role in GlcNAc (but not serum) induced hyphal growth; localizes to plasma membrane; induced by GlcNAc, macrophage engulfment; 12 transmembrane, major facilitator superfamily || 1 0.02 0.07 0.84 0.97 -0.66 -1.47 -0.71 -0.41 -0.68 -0.17 -1.16 -1.47 1.42 0.70 -1.09 -1.37
6163 || orf19.6494 || WHI3 || || Putative RNA binding protein; induced during infection of murine kidney, compared to growth in vitro; has murine homolog || 1 0.02 0.06 0.41 0.79 -1.12 -1.47 -0.32 -0.42 -0.23 0.41 -1.29 -0.94 0.31 0.18 -0.53 -0.71
6164 || orf19.6494 || WHI3 || || Putative RNA binding protein; induced during infection of murine kidney, compared to growth in vitro; has murine homolog || 1 0.28 0.19 0.40 0.83 -0.84 -0.92 -0.34 -0.38 -0.25 0.19 -0.88 -0.90 0.33 0.28 -0.37 -0.56
6165 || orf19.6494 || WHI3 || || Putative RNA binding protein; induced during infection of murine kidney, compared to growth in vitro; has murine homolog || 1 0.45 0.52 0.67 1.15 -0.90 -1.30 -0.02 -0.17 -0.28 0.29 -1.14 -0.97 0.65 0.23 -0.45 -0.87
6166 || orf19.6494 || WHI3 || || Putative RNA binding protein; induced during infection of murine kidney, compared to growth in vitro; has murine homolog || 1 0.45 0.29 0.27 0.79 -1.10 -1.24 0.01 -0.17 -0.14 0.40 -1.01 -0.98 0.56 0.22 -0.26 -0.76
6167 || orf19.1392 || || || Ortholog(s) have chaperone binding, protein disulfide isomerase activity, unfolded protein binding activity and role in ER-associated ubiquitin-dependent protein catabolic process, protein retention in ER lumen || 1 0.20 0.09 0.33 0.74 -0.80 -0.70 -0.19 -0.09 0.01 0.28 -0.71 -0.55 0.33 0.41 -0.29 -0.99
6168 || orf19.2738 || SUL2 || || Putative sulfate transporter; transcript negatively regulated by Sfu1; amphotericin B induced; F-12/CO2 and Spider biofilm induced || 1 1.01 1.01 1.09 1.36 -3.19 -3.20 -0.64 -0.70 -0.41 -0.30 -2.22 -4.22 0.79 0.98 -1.86 -3.87
6169 || orf19.2738 || SUL2 || || Putative sulfate transporter; transcript negatively regulated by Sfu1; amphotericin B induced; F-12/CO2 and Spider biofilm induced || 1 0.61 0.70 1.13 1.01 -4.11 -4.41 -0.87 -1.02 -0.47 -0.15 -3.48 -4.67 0.80 1.36 -2.06 -3.83
6170 || orf19.2738 || SUL2 || || Putative sulfate transporter; transcript negatively regulated by Sfu1; amphotericin B induced; F-12/CO2 and Spider biofilm induced || 1 0.71 0.72 1.07 1.19 -2.58 -3.55 -0.97 -1.08 -0.80 -0.35 -3.25 -3.91 0.61 1.11 -2.08 -3.42
6171 || orf19.2738 || SUL2 || || Putative sulfate transporter; transcript negatively regulated by Sfu1; amphotericin B induced; F-12/CO2 and Spider biofilm induced || 1 0.75 0.73 0.93 1.25 -1.73 -2.10 -0.57 -0.57 -0.27 -0.22 -2.11 -2.46 0.63 1.13 -1.06 -2.80
6172 || orf19.2738 || SUL2 || || Putative sulfate transporter; transcript negatively regulated by Sfu1; amphotericin B induced; F-12/CO2 and Spider biofilm induced || 1 0.87 1.16 0.98 1.11 -1.50 -2.53 -0.22 -0.31 -0.22 -0.14 -1.87 -3.24 1.32 1.22 -0.93 -2.76
6173 || orf19.7521 || REP1 || || Protein involved in negative regulation of MDR1 transcription; mutants show increased resistance to azole drugs || 1 0.85 0.85 0.79 0.23 -2.17 -2.78 0.03 -0.64 -0.29 0.57 -1.94 -2.32 1.76 0.54 -0.79 -2.23
6174 || orf19.7521 || REP1 || || Protein involved in negative regulation of MDR1 transcription; mutants show increased resistance to azole drugs || 1 0.94 0.90 1.08 0.64 -2.29 -2.32 0.17 -0.49 0.07 0.82 -2.94 -2.23 1.80 0.81 -1.03 -2.91
6175 || orf19.5992 || WOR2 || || Zn(II)2Cys6 transcription factor; regulator of white-opaque switching; required for maintenance of opaque state; Hap43-induced || 1 0.56 0.62 0.88 0.94 -2.47 -1.97 0.76 -0.13 0.48 0.04 -2.52 -1.59 1.71 0.54 -1.57 -2.18
6176 || orf19.2154 || HXK1 || || N-acetylglucosamine (GlcNAc) kinase; involved in GlcNAc utilization; required for wild-type hyphal growth and mouse virulence; GlcNAc-induced transcript; induced by alpha pheromone in SpiderM medium || 1 0.08 0.00 0.64 0.51 -0.80 -1.33 -0.45 -0.03 0.12 -0.08 -1.24 -0.77 0.29 0.61 -0.85 -1.47
6177 || orf19.7084 || DFI1 || || Cell-surface associated glycoprotein; promotes activation of Cek1 in a matrix-dependent manner; N-glycosylated; Spider biofilm induced || 1 0.01 -0.06 0.29 0.45 -0.53 -0.83 -0.28 -0.08 -0.26 0.23 -0.59 -0.77 0.03 0.31 -0.41 -0.75
6178 || orf19.7084 || DFI1 || || Cell-surface associated glycoprotein; promotes activation of Cek1 in a matrix-dependent manner; N-glycosylated; Spider biofilm induced || 1 0.09 0.02 0.11 0.35 -0.35 -0.91 -0.32 -0.06 -0.39 0.28 -0.56 -0.81 -0.01 0.27 -0.39 -0.74
6179 || orf19.5392 || NGT1 || || N-acetylglucosamine (GlcNAc)-specific transporter; role in GlcNAc (but not serum) induced hyphal growth; localizes to plasma membrane; induced by GlcNAc, macrophage engulfment; 12 transmembrane, major facilitator superfamily || 1 -0.42 -0.50 -0.12 -0.21 -2.22 -3.46 -1.32 -1.35 -1.24 0.01 -2.08 -1.79 1.54 1.50 -2.48 -1.81
6180 || orf19.4405 || PPS1 || || Putative dual specificity protein phosphatase, similar to S. cerevisiae Pps1p; mutant shows virulence defect || 1 -0.51 -0.49 -0.05 0.09 -4.08 -3.03 -0.20 -0.47 0.19 0.27 -3.21 -2.68 1.18 0.30 -3.26 -2.59
6181 || orf19.6079 || || || Predicted ORF in retrotransposon Tca8 with similarity to the Gag region encoding nucleocapsid-like protein; repressed by ciclopirox olamine; filament induced; regulated by Rfg1, Tup1; overlaps orf19.6078.1 || 1 -1.13 -1.17 0.76 0.11 -7.39 -7.27 -1.10 -2.29 0.65 -1.89 -5.98 -4.78 2.61 1.42 -6.08 -6.43
6182 || orf19.6079 || || || Predicted ORF in retrotransposon Tca8 with similarity to the Gag region encoding nucleocapsid-like protein; repressed by ciclopirox olamine; filament induced; regulated by Rfg1, Tup1; overlaps orf19.6078.1 || 1 -1.12 -1.11 0.66 0.25 -6.59 -7.79 -1.23 -2.60 0.81 -1.48 -7.16 -6.69 2.80 1.17 -6.59 -7.27
6183 || orf19.6078 || POL93 || || Predicted ORF in retrotransposon Tca8 with similarity to the Pol region of retrotransposons encoding reverse transcriptase, protease and integrase; downregulated in response to ciclopirox olamine; F-12/CO2 early biofilm induced || 1 -0.94 -1.05 1.15 0.71 -4.71 -3.15 -1.68 -1.96 1.02 -1.19 -5.19 -3.49 2.30 0.69 -3.75 -3.77
6184 || orf19.3522 || || || Protein of unknown function; flow model biofilm induced; transcript repressed by ciclopirox olamine || 1 -0.78 -0.83 0.05 -2.89 -1.29 -1.22 -0.31 -0.35 -1.79 1.46 0.77 -1.99
6185 || orf19.4666 || || || Protein of unknown function; hyphal-induced expression, regulated by Cyr1, Ras1, Efg1; Spider biofilm induced || 1 -0.86 -1.07 -0.35 -0.27 -2.71 -2.77 -0.48 -0.94 -0.68 -0.07 -1.63 -1.39 0.70 0.64 -1.92 -2.47
6186 || orf19.4666 || || || Protein of unknown function; hyphal-induced expression, regulated by Cyr1, Ras1, Efg1; Spider biofilm induced || 1 -0.87 -0.94 -0.14 -0.01 -3.03 -2.92 -0.64 -0.93 -0.74 -0.35 -1.72 -1.49 0.43 0.43 -1.79 -2.19
6187 || orf19.3305 || ZCF17 || || Putative Zn(II)2Cys6 transcription factor || 1 -0.08 -0.18 0.03 0.13 -1.33 -0.92 -0.17 -0.31 -0.28 0.18 -0.55 -0.32 0.13 0.12 -0.73 -0.55
6188 || orf19.5292 || AXL2 || || Ortholog of S. cerevisiae Axl2; a plasma membrane protein involved in determination of budding pattern; O-glycosylated by Pmt4; mutant is viable || 1 -0.17 -0.05 -0.05 0.39 -2.17 -2.34 -0.51 -0.51 -0.06 0.85 -1.29 -0.98 0.14 0.16 -1.87 -1.55
6189 || orf19.3732 || ERG25 || || Putative C-4 methyl sterol oxidase; C4-demethylation of ergosterol biosynthesis intermediates, based on similarity to S. cerevisiae Erg25; fluconazole-induced; induced in azole-resistant strain; rat catheter and Spider biofilm induced || 1 -0.28 -0.22 -0.42 0.22 -1.64 -1.71 -0.11 0.01 -0.05 0.70 -0.90 -0.79 0.38 0.11 -0.98 -1.53
6190 || orf19.6494 || WHI3 || || Putative RNA binding protein; induced during infection of murine kidney, compared to growth in vitro; has murine homolog || 1 -0.05 -0.02 -0.24 0.26 -1.47 -1.74 -0.40 -0.58 -0.51 0.37 -1.43 -1.22 0.30 0.32 -0.75 -1.05
6191 || orf19.5292 || AXL2 || || Ortholog of S. cerevisiae Axl2; a plasma membrane protein involved in determination of budding pattern; O-glycosylated by Pmt4; mutant is viable || 1 0.25 0.27 -0.28 0.12 -1.45 -2.27 -0.01 -0.14 -0.42 0.41 -1.24 -1.38 0.63 -0.32 -1.27 -1.15
6192 || orf19.2459 || || || Protein of unknown function; mRNA binds to She3; Hap43 repressed gene; Spider biofilm induced || 1 -0.09 -0.15 -0.12 0.02 -1.38 -1.36 0.09 -0.59 0.13 0.23 -0.91 -0.84 0.61 0.08 -0.65 -0.69
6193 || orf19.2459 || || || Protein of unknown function; mRNA binds to She3; Hap43 repressed gene; Spider biofilm induced || 1 0.34 0.09 -0.41 -0.10 -1.64 -1.56 0.09 -0.42 0.16 0.40 -0.83 -1.01 0.89 0.09 -0.84 -0.72
6194 || orf19.2459 || || || Protein of unknown function; mRNA binds to She3; Hap43 repressed gene; Spider biofilm induced || 1 0.14 0.22 -0.32 -0.19 -1.25 -1.49 0.20 -0.19 0.29 0.36 -0.78 -1.04 0.77 0.13 -0.47 -1.31
6195 || orf19.2459 || || || Protein of unknown function; mRNA binds to She3; Hap43 repressed gene; Spider biofilm induced || 1 0.49 0.36 0.06 0.06 -1.81 -1.42 0.42 -0.18 0.47 0.57 -0.70 -0.97 0.69 0.25 -0.52 -0.80
6196 || orf19.5741 || ALS1 || || Cell-surface adhesin; adhesion, virulence, immunoprotective roles; band at hyphal base; Rfg1, Ssk1, Spider biofilm induced; flow model biofilm repressed; CAI-4 strain background effects; promoter bound Bcr1, Tec1, Efg1, Ndt80, and Brg1 || 1 -0.00 0.06 0.36 -0.31 -2.85 -2.38 0.73 -0.03 0.93 0.35 -2.05 -1.30 0.95 0.74 -0.73 -1.37
6197 || orf19.5741 || ALS1 || || Cell-surface adhesin; adhesion, virulence, immunoprotective roles; band at hyphal base; Rfg1, Ssk1, Spider biofilm induced; flow model biofilm repressed; CAI-4 strain background effects; promoter bound Bcr1, Tec1, Efg1, Ndt80, and Brg1 || 1 0.10 0.02 0.39 0.15 -2.62 -2.28 0.51 0.11 0.89 0.41 -1.42 -1.39 0.84 0.41 -0.87 -2.55
6198 || orf19.5994 || RHB1 || || Putative small G protein from the Ras superfamily involved in cell wall integrity and control of filamentous growth under nitrogen starvation || 1 0.44 0.40 0.31 0.46 -3.28 -1.76 0.15 0.31 0.38 0.73 -2.00 -1.26 0.97 0.50 -0.54 -2.01
6199 || orf19.5994 || RHB1 || || Putative small G protein from the Ras superfamily involved in cell wall integrity and control of filamentous growth under nitrogen starvation || 1 -0.07 -0.01 0.09 -0.13 -3.25 -2.27 -0.24 -0.25 0.34 0.45 -1.99 -1.29 0.52 0.10 -0.72 -2.00
6200 || orf19.5741 || ALS1 || || Cell-surface adhesin; adhesion, virulence, immunoprotective roles; band at hyphal base; Rfg1, Ssk1, Spider biofilm induced; flow model biofilm repressed; CAI-4 strain background effects; promoter bound Bcr1, Tec1, Efg1, Ndt80, and Brg1 || 1 0.16 0.46 0.35 -0.20 -1.62 -1.55 -0.24 -0.50 0.30 0.12 -1.48 -0.86 0.39 0.41 -0.86 -2.24
6201 || orf19.5995 || MCA1 || || Putative cysteine protease with similarity to S. cerevisiae Mca1p; has a role in apoptotic cell death upon H2O2 treatment; fungal-specific (no human or murine homolog); farnesol-induced || 1 -0.00 -0.04 -0.07 -0.13 -1.00 -1.00 0.13 -0.26 -0.39 -0.11 -1.18 -0.84 -0.20 -0.01 -0.79 -1.21
6202 || orf19.6741 || || || Putative plasma membrane protein; predicted role in cell wall integrity; regulated by Nrg1, Tup1; induced during chlamydospore formation in both C. albicans and C. dubliniensis || 1 -0.55 -0.68 -1.00 -0.41 -2.60 -3.83 -0.42 -0.13 -0.16 0.51 -2.66 -2.42 0.22 0.21 -2.29 -3.19
6203 || orf19.413 || || || Protein of unknown function; induced by Sfu1; Spider biofilm induced || 1 -0.38 -0.52 -0.34 -0.58 -1.71 -2.46 0.36 0.05 0.31 0.28 -1.98 -2.23 0.77 0.34 -1.25 -1.72
6204 || orf19.413 || || || Protein of unknown function; induced by Sfu1; Spider biofilm induced || 1 -0.50 -0.56 -0.65 -0.50 -3.54 -3.27 0.43 0.06 0.25 0.28 -3.47 -3.73 1.20 -0.10 -2.63 -3.69
6205 || orf19.4607 || || || Possible Golgi membrane protein; Hap43-repressed; hypha induced; flow model biofilm induced; Spider biofilm induced || 1 -0.24 -0.45 0.28 -0.08 -2.82 -3.28 0.43 0.63 1.00 0.43 -2.77 -2.97 0.18 0.73 -2.63 -2.70
6206 || orf19.4607 || || || Possible Golgi membrane protein; Hap43-repressed; hypha induced; flow model biofilm induced; Spider biofilm induced || 1 -0.21 -0.38 -0.25 -0.40 -2.77 -4.17 0.62 0.86 1.24 0.73 -2.52 -2.96 0.34 0.81 -2.17 -2.55
6207 || orf19.2475 || PGA26 || || GPI-anchored adhesin-like protein of the cell wall; role in cell wall integrity; required for normal virulence; induced in high iron and during cell wall regeneration; Hap43-repressed || 1 -0.56 -0.73 -0.63 -0.75 -2.61 -4.39 0.43 0.86 0.40 0.68 -2.81 -3.32 0.07 0.61 -2.67 -2.46
6208 || orf19.2475 || PGA26 || || GPI-anchored adhesin-like protein of the cell wall; role in cell wall integrity; required for normal virulence; induced in high iron and during cell wall regeneration; Hap43-repressed || 1 -0.78 -0.87 -1.10 -0.92 -3.15 -3.92 0.93 1.38 0.73 0.87 -2.85 -3.31 0.52 0.73 -3.29 -2.26
6209 || orf19.2669 || || || ORF in retrotransposon Tca4; similar to Pol region of retrotransposons encoding reverse transcriptase, protease, integrase; downstream of RHD2, similar to the Gag region encoding nucleocapsid-like protein; rat catheter biofilm induced || 1 -0.51 -0.29 -0.89 -1.04 -3.56 -3.19 1.35 1.54 1.26 1.39 -4.51 -3.36 0.83 0.84 -4.13 -4.32
6210 || orf19.2669 || || || ORF in retrotransposon Tca4; similar to Pol region of retrotransposons encoding reverse transcriptase, protease, integrase; downstream of RHD2, similar to the Gag region encoding nucleocapsid-like protein; rat catheter biofilm induced || 1 -0.31 -0.26 -1.41 -1.26 -5.28 -6.39 1.61 2.02 1.09 1.23 -6.11 -6.44 0.95 1.08 -6.63 -6.36
6211 || orf19.2669 || || || ORF in retrotransposon Tca4; similar to Pol region of retrotransposons encoding reverse transcriptase, protease, integrase; downstream of RHD2, similar to the Gag region encoding nucleocapsid-like protein; rat catheter biofilm induced || 1 -0.50 -0.44 -1.32 -0.97 -3.47 -4.43 1.41 1.48 0.76 1.00 -3.98 -5.11 0.71 0.65 -3.54 -5.04
6212 || orf19.2669 || || || ORF in retrotransposon Tca4; similar to Pol region of retrotransposons encoding reverse transcriptase, protease, integrase; downstream of RHD2, similar to the Gag region encoding nucleocapsid-like protein; rat catheter biofilm induced || 1 -0.54 -0.17 -1.34 -1.06 -3.70 -3.59 1.41 1.85 0.73 1.09 -3.36 -4.41 0.59 0.67 -2.32 -4.66
6213 || orf19.3733 || IDP2 || || Isocitrate dehydrogenase; white-opaque switch regulated; morphology-regulation by Ssn6; protein in exponential and stationary phase yeast; Hap43-repressed; Spider biofilm repressed by Bcr1, Tec1, Ndt80, Rob1, Brg1; Spider biofilm induced || 1 -0.65 -0.41 -0.31 -0.13 -2.33 -2.92 0.81 1.15 1.22 1.23 -1.98 -2.09 0.57 0.09 -2.20 -2.38
6214 || orf19.3733 || IDP2 || || Isocitrate dehydrogenase; white-opaque switch regulated; morphology-regulation by Ssn6; protein in exponential and stationary phase yeast; Hap43-repressed; Spider biofilm repressed by Bcr1, Tec1, Ndt80, Rob1, Brg1; Spider biofilm induced || 1 -1.01 -0.81 -0.85 -0.30 -3.74 -3.89 0.94 1.15 0.76 0.79 -2.28 -2.53 0.28 -0.24 -2.67 -2.43
6215 || orf19.2475 || PGA26 || || GPI-anchored adhesin-like protein of the cell wall; role in cell wall integrity; required for normal virulence; induced in high iron and during cell wall regeneration; Hap43-repressed || 1 -1.29 -1.30 -1.69 -1.45 -4.27 -5.70 0.29 0.76 0.26 0.54 -3.95 -3.95 -0.14 0.26 -4.26 -2.53
6216 || orf19.2475 || PGA26 || || GPI-anchored adhesin-like protein of the cell wall; role in cell wall integrity; required for normal virulence; induced in high iron and during cell wall regeneration; Hap43-repressed || 1 -1.42 -1.53 -1.36 -1.21 -4.38 -5.76 0.38 0.73 0.24 0.67 -3.70 -3.67 -0.10 0.60 -4.32 -2.52
6217 || orf19.6990 || || || Putative peptidyl-prolyl cis-trans isomerase; predicted endoplasmic reticulum (ER) localization || 1 -0.45 -0.42 -0.10 -0.21 -0.66 -1.19 0.13 0.35 -0.08 0.07 -0.83 -0.82 -0.01 0.14 -1.09 -0.72
6218 || orf19.105 || HAL22 || || Putative phosphoadenosine-5'-phosphate or 3'-phosphoadenosine 5'-phosphosulfate phosphatase; possible role in sulfur recycling; Hap43-repressed; F-12/CO2 biofilm induced || 1 -0.26 -0.33 -0.47 -0.01 -1.05 -1.79 0.42 0.84 0.29 0.48 -0.73 -1.42 -0.07 0.51 -1.29 -1.82
6219 || orf19.5138 || IFA21 || || IPF family A protein; mutants are viable; Spider biofilm induced || 1 -0.50 -0.77 -0.66 -0.23 -1.24 -1.85 0.63 0.80 0.51 0.47 -0.69 -0.81 -0.17 0.43 -1.07 -1.67
6220 || orf19.102 || || || Ortholog(s) have translation regulator activity, role in regulation of translation and mitochondrion localization || 1 -0.23 -0.21 -1.22 -0.66 -1.84 -2.89 0.84 0.93 0.95 1.13 -1.24 -1.70 0.38 0.37 -1.13 -2.15
6221 || orf19.102 || || || Ortholog(s) have translation regulator activity, role in regulation of translation and mitochondrion localization || 1 0.01 -0.24 -1.21 -0.80 -2.05 -4.64 0.84 1.12 0.69 1.31 -2.27 0.31 1.08 -1.38 -2.57
6222 || orf19.4255 || ECM331 || || GPI-anchored protein; mainly at plasma membrane, also at cell wall; Hap43, caspofungin-induced; Plc1-regulated; Hog1, Rim101-repressed; colony morphology-related regulated by Ssn6; induced by ketoconazole and hypoxia || 1 -0.23 -0.04 0.00 0.12 -1.19 -2.27 0.65 0.56 0.44 0.86 -1.11 -0.91 0.09 0.21 -0.62 -1.53
6223 || orf19.2669 || || || ORF in retrotransposon Tca4; similar to Pol region of retrotransposons encoding reverse transcriptase, protease, integrase; downstream of RHD2, similar to the Gag region encoding nucleocapsid-like protein; rat catheter biofilm induced || 1 -0.05 0.06 -0.85 -0.88 -2.88 -5.42 1.58 1.92 1.24 1.41 -2.34 -5.34 0.75 0.82 -2.33 -6.94
6224 || orf19.2668 || RHD2 || || Predicted ORF in retrotransposon Tca4 with similarity to the Gag region encoding nucleocapsid-like protein; overlaps blocked reading frame orf19.2668.1; yeast-enriched transcript; rat catheter biofilm induced || 1 -0.04 -0.19 -0.47 -0.45 -2.51 -6.25 2.15 2.39 1.20 1.46 -2.30 -5.78 0.93 0.87 -2.70 -4.08
6225 || orf19.2668 || RHD2 || || Predicted ORF in retrotransposon Tca4 with similarity to the Gag region encoding nucleocapsid-like protein; overlaps blocked reading frame orf19.2668.1; yeast-enriched transcript; rat catheter biofilm induced || 1 -0.38 -0.37 -1.28 -1.00 -4.34 1.85 1.92 1.08 1.23 -2.81 -8.78 1.22 0.78 -3.48 -5.03
6226 || orf19.4070 || || || Ortholog of C. dubliniensis CD36 : Cd36_23270 || 1 0.09 0.05 -1.32 -0.51 -1.91 0.27 1.69 1.47 1.09 -2.84 -3.74 0.39 -0.03 -1.67 -3.16
6227 || orf19.4607 || || || Possible Golgi membrane protein; Hap43-repressed; hypha induced; flow model biofilm induced; Spider biofilm induced || 1 0.23 0.52 -0.24 -0.34 -2.07 -2.62 0.69 0.56 1.31 0.69 -1.18 -2.16 0.81 0.98 -1.18 -1.97
6228 || orf19.5933 || || || Protein of unknown function; transcript induced by benomyl treatment || 1 0.49 0.00 0.12 -0.25 -1.13 -1.43 0.58 0.53 0.22 0.72 -1.01 -1.34 0.63 0.59 -0.83 -0.96
6229 || orf19.938 || || || Ortholog of C. dubliniensis CD36 : Cd36_50520, C. parapsilosis CDC317 : CPAR2_304000, Candida tenuis NRRL Y-1498 : cten_CGOB_00233 and Debaryomyces hansenii CBS767 : DEHA2E12408g || 1 0.18 0.20 0.08 -0.09 -2.27 -3.57 1.30 0.38 0.17 0.01 -1.89 -2.90 2.12 1.46 -2.80 -1.56
6230 || orf19.938 || || || Ortholog of C. dubliniensis CD36 : Cd36_50520, C. parapsilosis CDC317 : CPAR2_304000, Candida tenuis NRRL Y-1498 : cten_CGOB_00233 and Debaryomyces hansenii CBS767 : DEHA2E12408g || 1 0.18 0.30 0.24 0.36 -2.84 -3.84 1.23 0.45 0.81 0.22 -2.16 -3.71 2.02 1.62 -3.25 -2.85
6231 || orf19.3127 || CZF1 || || Transcription factor; regulates white-opaque switch; hyphal growth regulator; expression in S. cerevisiae causes dominant-negative inhibition of pheromone response; required for yeast cell adherence to silicone; Spider biofilm induced || 1 -0.09 -0.17 0.00 -0.06 -2.53 -2.65 0.80 0.21 0.73 0.36 -0.89 -1.56 1.00 0.71 -1.74 -1.99
6232 || orf19.3127 || CZF1 || || Transcription factor; regulates white-opaque switch; hyphal growth regulator; expression in S. cerevisiae causes dominant-negative inhibition of pheromone response; required for yeast cell adherence to silicone; Spider biofilm induced || 1 -0.40 -0.38 0.06 0.07 -3.20 -2.86 0.78 -0.10 0.48 0.16 -1.52 -1.82 1.05 0.40 -2.73 -2.12
6233 || orf19.938 || || || Ortholog of C. dubliniensis CD36 : Cd36_50520, C. parapsilosis CDC317 : CPAR2_304000, Candida tenuis NRRL Y-1498 : cten_CGOB_00233 and Debaryomyces hansenii CBS767 : DEHA2E12408g || 1 0.09 0.11 0.35 0.57 -1.41 -1.77 0.51 0.02 0.71 0.63 -1.16 -1.22 0.92 0.86 -1.79 -2.00
6234 || orf19.5169 || || || Ortholog(s) have cytosol, nucleus localization || 1 0.15 0.17 0.62 1.00 -1.34 -1.42 0.65 0.26 0.58 0.14 -1.24 -0.68 0.48 0.25 -1.64 -1.10
6235 || orf19.5169 || || || Ortholog(s) have cytosol, nucleus localization || 1 0.44 0.36 0.88 1.57 -1.93 -1.76 0.37 0.22 0.46 -0.20 -2.17 -0.66 0.51 -0.41 -1.98 -1.25
6236 || orf19.5169 || || || Ortholog(s) have cytosol, nucleus localization || 1 0.17 0.38 0.42 1.06 -1.96 -2.43 0.45 0.07 0.20 -0.17 -1.86 -1.27 0.26 -0.34 -2.14 -1.64
6237 || orf19.5903 || RAX1 || || Protein with a predicted role in bud site selection; hypha-induced expression; Spider biofilm induced || 1 0.07 -0.06 0.19 0.46 -1.13 -1.11 -0.07 -0.05 0.26 0.06 -0.81 -0.39 0.09 0.03 -0.72 -0.77
6238 || orf19.3174 || CDC24 || || GDP-GTP exchange factor for Cdc42p; phosphorylated; required for maintenance of hyphal growth; misexpression blocks hyphal growth and causes avirulence in a mouse model of systemic infection; antigenic during human oral infection || 1 -0.15 -0.24 0.16 0.17 -0.83 -1.10 -0.13 0.11 -0.11 0.01 -0.61 -0.65 0.16 0.41 -0.55 -0.67
6239 || orf19.6958 || ECM18 || || Ortholog(s) have mitochondrion localization || 1 -0.25 -0.16 0.25 0.47 -1.12 -1.37 0.15 0.09 0.18 -0.10 -0.71 -1.09 -0.05 0.39 -0.88 -0.88
6240 || orf19.3378 || || || Protein of unknown function; regulated by Tsa1, Tsa1B in minimal media at 37 degrees C || 1 0.03 0.02 0.97 1.09 -3.04 -3.62 0.76 0.71 0.04 -0.67 -2.06 -1.56 -0.06 0.60 -2.43 -2.29
6241 || orf19.3378 || || || Protein of unknown function; regulated by Tsa1, Tsa1B in minimal media at 37 degrees C || 1 -0.32 0.02 1.05 0.58 -2.72 -3.44 0.53 0.33 0.19 -0.54 -2.09 -1.84 -0.03 1.30 -2.76 -3.12
6242 || orf19.3378 || || || Protein of unknown function; regulated by Tsa1, Tsa1B in minimal media at 37 degrees C || 1 -0.07 -0.03 0.73 0.60 -2.27 0.95 0.69 0.27 -0.77 -2.49 -2.15 0.13 1.21 -2.80 -2.73
6243 || orf19.4975 || HYR1 || || GPI-anchored hyphal cell wall protein; macrophage-induced; repressed by neutrophils; resistance to killing by neutrophils, azoles; regulated by Rfg1, Efg1, Nrg1, Tup1, Cyr1, Bcr1, Hap43; Spider and flow model biofilm induced || 1 0.44 0.50 1.24 0.76 -1.57 -1.51 -0.20 -0.58 0.60 -0.60 -2.70 -2.34 -0.08 0.03 -1.85 -1.20
6244 || orf19.5791 || IDH2 || || Putative mitochondrial NAD-isocitrate dehydrogenase subunit; induced by ciclopirox; induced in high iron; present in exponential and stationary growth phases; Spider biofilm repressed || 1 0.10 -0.01 0.43 0.57 -0.76 -0.58 -0.22 -0.03 0.06 0.04 -1.46 -1.46 -0.15 0.15 -1.58 -0.83
6245 || orf19.3444 || || || Predicted membrane transporter, member of the drug:proton antiporter (14 spanner) (DHA2) family, major facilitator superfamily (MFS); Hap43p-repressed gene || 1 0.09 0.15 0.85 0.95 -1.68 -1.51 -0.28 -0.64 0.46 -0.13 -3.10 -2.61 -0.88 0.05 -2.84 -2.28
6246 || orf19.7668 || MAL2 || || Alpha-glucosidase; hydrolyzes sucrose for sucrose utilization; transcript regulated by Suc1, induced by maltose, repressed by glucose; Tn mutation affects filamentous growth; upregulated in RHE model; rat catheter and Spider biofilm induced || 1 0.68 0.70 0.81 0.86 -1.28 -1.27 -0.23 -0.14 0.25 0.32 -2.07 -1.56 -0.61 0.26 -1.52 -1.38
6247 || orf19.3309 || || || Ortholog of Candida tropicalis MYA-3404 : CTRG_04422 and Candida albicans WO-1 : CAWG_01254 || 1 0.48 0.39 0.47 0.36 -1.08 -1.43 -0.13 -0.25 0.44 0.40 -2.49 -1.92 -0.15 0.33 -1.84 -1.65
6248 || orf19.3309 || || || Ortholog of Candida tropicalis MYA-3404 : CTRG_04422 and Candida albicans WO-1 : CAWG_01254 || 1 0.44 0.47 0.41 0.34 -0.52 -1.08 0.14 -0.12 0.42 0.37 -1.73 -1.41 0.02 0.44 -1.07 -0.76
6249 || orf19.2457 || || || Protein of unknown function; induced during chlamydospore formation in both C. albicans and C. dubliniensis; Spider biofilm induced || 1 1.80 1.76 0.69 0.74 -2.33 -2.60 0.53 0.26 0.47 1.83 -2.36 -4.23 -0.02 -0.17 -2.12 -2.81
6250 || orf19.2457 || || || Protein of unknown function; induced during chlamydospore formation in both C. albicans and C. dubliniensis; Spider biofilm induced || 1 1.89 1.71 0.41 0.74 -2.43 -3.50 0.63 0.05 0.65 1.46 -3.63 -4.53 0.61 -0.42 -3.10 -3.67
6251 || orf19.2457 || || || Protein of unknown function; induced during chlamydospore formation in both C. albicans and C. dubliniensis; Spider biofilm induced || 1 1.60 1.66 0.63 0.45 -3.39 -4.09 0.61 -0.02 0.73 1.51 -3.58 -4.17 0.53 -0.23 -2.83 -3.12
6252 || orf19.4405 || PPS1 || || Putative dual specificity protein phosphatase, similar to S. cerevisiae Pps1p; mutant shows virulence defect || 1 0.72 0.88 0.61 0.43 -3.06 -3.07 0.20 0.54 1.09 0.46 -2.66 -3.17 1.86 0.31 -2.73 -2.35
6253 || orf19.467 || WOR3 || || Transcription factor; modulator of white-opaque switch; induced in opaque cells; promoter bound by Wor1; overexpression at 25 degr shifts cells to opaque state; deletion stabilizes opaque cells at higher temperatures; Spider biofilm induced || 1 1.54 1.49 1.36 1.87 -1.88 -3.16 1.07 0.39 1.33 1.00 -2.60 -3.48 1.77 0.76 -1.99 -3.14
6254 || orf19.4972 || || || Putative transcription factor with zinc finger DNA-binding motif || 1 1.57 1.55 1.56 1.37 -2.69 -4.34 1.07 0.90 1.12 0.65 -2.68 -4.71 1.30 0.32 -2.70 -3.34
6255 || orf19.467 || WOR3 || || Transcription factor; modulator of white-opaque switch; induced in opaque cells; promoter bound by Wor1; overexpression at 25 degr shifts cells to opaque state; deletion stabilizes opaque cells at higher temperatures; Spider biofilm induced || 1 1.84 1.89 1.33 1.39 -3.45 -4.75 1.78 0.63 1.32 1.04 -3.59 -4.33 2.27 0.66 -3.18 -4.19
6256 || orf19.467 || WOR3 || || Transcription factor; modulator of white-opaque switch; induced in opaque cells; promoter bound by Wor1; overexpression at 25 degr shifts cells to opaque state; deletion stabilizes opaque cells at higher temperatures; Spider biofilm induced || 1 1.67 1.80 1.16 1.45 -4.22 -5.19 1.62 0.59 1.15 0.87 -4.30 -5.03 1.91 0.50 -3.64 -4.56
6257 || orf19.467 || WOR3 || || Transcription factor; modulator of white-opaque switch; induced in opaque cells; promoter bound by Wor1; overexpression at 25 degr shifts cells to opaque state; deletion stabilizes opaque cells at higher temperatures; Spider biofilm induced || 1 1.70 1.71 1.31 1.52 -5.11 -5.73 1.59 0.43 1.38 0.94 -4.86 -5.52 2.16 0.57 -4.54 -5.98
6258 || orf19.467 || WOR3 || || Transcription factor; modulator of white-opaque switch; induced in opaque cells; promoter bound by Wor1; overexpression at 25 degr shifts cells to opaque state; deletion stabilizes opaque cells at higher temperatures; Spider biofilm induced || 1 1.85 1.94 1.29 1.65 -4.06 -4.56 1.57 0.80 1.41 1.05 -4.04 -4.22 2.17 0.91 -4.02 -4.96
6259 || orf19.1539 || || || Protein of unknown function; F-12/CO2 early biofilm induced || 1 0.81 0.69 0.58 0.56 -1.45 -2.27 0.64 0.28 0.98 0.99 -2.04 -2.71 1.03 0.13 -1.60 -2.56
6260 || orf19.6277 || || || Has domain(s) with predicted phosphatidylinositol binding activity and role in cell communication || 1 1.11 0.83 0.28 0.49 -2.29 -3.79 0.81 0.61 0.27 0.32 -3.44 -2.53 0.50 0.10 -2.45 -3.38
6261 || orf19.6277 || || || Has domain(s) with predicted phosphatidylinositol binding activity and role in cell communication || 1 1.01 0.96 0.57 1.22 -3.84 -4.29 0.81 0.83 0.76 0.74 -3.41 -2.67 0.73 -0.01 -2.89 -3.44
6262 || orf19.6277 || || || Has domain(s) with predicted phosphatidylinositol binding activity and role in cell communication || 1 1.07 0.92 0.26 0.67 -2.67 -3.85 1.02 0.96 0.95 0.88 -2.83 -2.14 0.83 0.70 -2.10 -2.78
6263 || orf19.1701 || RKI1 || || Ortholog(s) have ribose-5-phosphate isomerase activity, role in pentose-phosphate shunt, pyridoxine biosynthetic process and cytoplasm, nucleus localization || 1 0.76 0.66 0.22 0.20 -1.45 -2.24 0.62 0.65 0.49 0.47 -1.47 -1.64 -0.07 0.34 -1.33 -1.38
6264 || orf19.4972 || || || Putative transcription factor with zinc finger DNA-binding motif || 1 1.33 1.32 1.38 1.25 -2.17 -5.85 1.04 0.57 1.07 0.90 -4.42 -4.89 1.08 0.51 -3.28
6265 || orf19.6277 || || || Has domain(s) with predicted phosphatidylinositol binding activity and role in cell communication || 1 1.50 1.49 0.77 1.05 -1.50 -3.72 1.37 1.18 0.87 0.75 -2.38 -2.69 0.83 0.34 -2.63 -3.66
6266 || orf19.1539 || || || Protein of unknown function; F-12/CO2 early biofilm induced || 1 0.18 0.25 0.25 0.05 -1.10 -1.46 0.31 0.06 0.59 0.38 -1.68 -1.45 0.71 0.11 -0.96 -1.92
6267 || orf19.4972 || || || Putative transcription factor with zinc finger DNA-binding motif || 1 1.08 1.12 0.80 0.94 -5.22 -5.00 0.74 0.42 1.27 1.01 -6.02 -4.21 0.69 0.22 -4.94 -8.15
6268 || orf19.6741 || || || Putative plasma membrane protein; predicted role in cell wall integrity; regulated by Nrg1, Tup1; induced during chlamydospore formation in both C. albicans and C. dubliniensis || 1 0.04 0.05 0.58 1.10 -1.17 -1.72 0.06 0.28 0.36 0.56 -1.04 -1.36 0.49 0.35 -0.74 -1.96
6269 || orf19.1313 || CDR3 || || Transporter of the Pdr/Cdr family of the ATP-binding cassette superfamily; transports phospholipids out-to-in; expressed in opaque-phase cells; induced by macrophage interaction; fluconazole-repressed; Spider biofilm induced || 1 0.10 0.17 0.56 1.41 -1.22 -2.26 0.01 0.38 0.39 1.00 -1.99 -2.31 0.43 0.11 -1.49 -2.53
6270 || orf19.1313 || CDR3 || || Transporter of the Pdr/Cdr family of the ATP-binding cassette superfamily; transports phospholipids out-to-in; expressed in opaque-phase cells; induced by macrophage interaction; fluconazole-repressed; Spider biofilm induced || 1 0.19 0.20 0.67 1.11 -1.15 -1.91 0.20 0.33 0.15 0.64 -1.83 -2.57 0.12 -0.07 -1.50 -2.21
6271 || orf19.5140 || || || Protein of unknown function; rat catheter and Spider biofilm induced || 1 0.51 0.43 0.71 0.99 -2.06 -2.39 0.58 -0.03 1.01 0.63 -3.59 -4.28 -0.14 -0.79 -2.23 -4.04
6272 || orf19.5140 || || || Protein of unknown function; rat catheter and Spider biofilm induced || 1 0.46 0.46 0.74 1.15 -1.32 -1.96 0.42 -0.11 0.67 0.56 -2.12 -2.87 -0.23 -0.83 -1.13 -2.66
6273 || orf19.5140 || || || Protein of unknown function; rat catheter and Spider biofilm induced || 1 0.51 0.35 1.00 1.43 -1.68 -1.89 0.38 -0.09 0.74 0.45 -2.04 -2.87 -0.42 -0.80 -1.72 -3.18
6274 || orf19.5140 || || || Protein of unknown function; rat catheter and Spider biofilm induced || 1 0.69 0.42 1.27 1.85 -1.83 -1.86 0.49 -0.12 1.15 0.71 -2.78 -2.90 -0.11 -1.03 -1.89 -3.32
6275 || orf19.5302 || PGA31 || || Cell wall protein; putative GPI anchor; expression regulated upon white-opaque switch; induced by Congo Red and cell wall regeneration; Bcr1-repressed in RPMI a/a biofilms || 1 1.20 0.99 1.34 2.32 -4.03 -5.14 -1.08 0.25 -0.19 0.45 -4.86 -5.33 -2.17 -2.11 -4.81 -3.94
6276 || orf19.5302 || PGA31 || || Cell wall protein; putative GPI anchor; expression regulated upon white-opaque switch; induced by Congo Red and cell wall regeneration; Bcr1-repressed in RPMI a/a biofilms || 1 1.08 1.10 1.00 1.99 -4.78 -6.28 -1.23 -0.01 -0.22 0.25 -5.20 -6.32 -2.33 -2.29 -5.39 -4.10
6277 || orf19.5302 || PGA31 || || Cell wall protein; putative GPI anchor; expression regulated upon white-opaque switch; induced by Congo Red and cell wall regeneration; Bcr1-repressed in RPMI a/a biofilms || 1 1.09 1.00 0.97 2.08 -6.34 -7.45 -1.23 0.09 -0.16 0.49 -5.80 -6.28 -2.71 -2.07 -6.06 -4.55
6278 || orf19.3902 || MRV2 || || Protein of unknown function; repressed by fluphenazine treatment or in an azole-resistant strain that overexpresses CDR1 and CDR2; Spider biofilm induced || 1 0.83 0.71 0.50 0.94 -5.36 -6.27 0.53 -0.06 1.03 0.83 -5.44 -5.87 -2.39 -1.26 -6.24 -5.25
6279 || orf19.3902 || MRV2 || || Protein of unknown function; repressed by fluphenazine treatment or in an azole-resistant strain that overexpresses CDR1 and CDR2; Spider biofilm induced || 1 0.28 0.46 0.28 0.91 -5.10 -6.12 0.57 0.05 0.91 0.88 -5.52 -5.86 -2.12 -1.40 -5.61 -5.37
6280 || orf19.3902 || MRV2 || || Protein of unknown function; repressed by fluphenazine treatment or in an azole-resistant strain that overexpresses CDR1 and CDR2; Spider biofilm induced || 1 0.80 0.56 0.48 1.03 -4.82 -5.41 0.54 0.01 0.89 0.82 -5.06 -5.81 -2.31 -1.25 -4.75 -5.01
6281 || orf19.3902 || MRV2 || || Protein of unknown function; repressed by fluphenazine treatment or in an azole-resistant strain that overexpresses CDR1 and CDR2; Spider biofilm induced || 1 1.06 0.79 1.17 1.75 -5.35 -6.24 0.42 -0.02 1.10 0.75 -5.79 -5.94 -2.16 -1.53 -6.05 -6.33
6282 || orf19.3902 || MRV2 || || Protein of unknown function; repressed by fluphenazine treatment or in an azole-resistant strain that overexpresses CDR1 and CDR2; Spider biofilm induced || 1 0.74 0.64 0.70 0.98 -2.17 -3.58 0.49 -0.04 0.82 0.85 -3.09 -4.15 -1.39 -1.24 -2.71 -3.83
6283 || orf19.6274 || PBR1 || || Protein of unknown function; required for cohesion, adhesion, and RPMI biofilm formation; induced by alpha pheromone in white cells; fluconazole-induced; Spider biofilm induced || 1 0.30 0.24 0.09 0.76 -4.72 -5.28 0.09 -1.87 1.11 0.03 -6.56 -6.46 -0.23 -2.26 -6.15 -5.81
6284 || orf19.6274 || PBR1 || || Protein of unknown function; required for cohesion, adhesion, and RPMI biofilm formation; induced by alpha pheromone in white cells; fluconazole-induced; Spider biofilm induced || 1 1.09 0.97 0.44 1.03 -6.52 -7.72 0.33 -1.17 1.70 0.27 -7.23 -8.49 0.44 -2.48 -6.39 -8.59
6285 || orf19.6274 || PBR1 || || Protein of unknown function; required for cohesion, adhesion, and RPMI biofilm formation; induced by alpha pheromone in white cells; fluconazole-induced; Spider biofilm induced || 1 0.94 0.91 0.34 1.24 -7.05 -8.18 0.28 -1.26 1.87 0.46 -6.83 -8.78 0.56 -2.65 -6.01 -4.64
6286 || orf19.5760 || IHD1 || || GPI-anchored protein; alkaline, hypha-induced; regulated by Nrg1, Rfg1, Tup1 and Tsa1, Tsa1B in minimal media at 37; oralpharyngeal candidasis induced ; Spider biofilm induced; regulated in Spider biofilms by Tec1, Efg1, Ndt80, Rob1, Brg1 || 1 1.35 1.36 0.97 1.48 -4.72 -4.96 -0.76 -0.70 -0.65 -0.04 -4.36 -5.37 0.73 -0.78 -5.08 -4.93
6287 || orf19.5144 || PGA28 || || Protein similar to S. cerevisiae Wsc2p, which has roles in stress- and cell-wall-related processes; predicted Kex2p substrate; putative GPI-anchored adhesin-like protein || 1 1.28 1.27 1.56 2.03 -5.41 -4.86 -1.26 -0.77 -0.61 0.29 -5.64 -5.48 -0.91 -0.71 -5.10 -5.68
6288 || orf19.5144 || PGA28 || || Protein similar to S. cerevisiae Wsc2p, which has roles in stress- and cell-wall-related processes; predicted Kex2p substrate; putative GPI-anchored adhesin-like protein || 1 1.09 1.11 1.62 1.93 -3.17 -3.67 -1.31 -0.81 -0.57 0.12 -4.00 -4.56 -0.71 -1.13 -3.54 -4.11
6289 || orf19.5144 || PGA28 || || Protein similar to S. cerevisiae Wsc2p, which has roles in stress- and cell-wall-related processes; predicted Kex2p substrate; putative GPI-anchored adhesin-like protein || 1 1.23 1.17 1.68 2.16 -2.84 -3.48 -1.08 -0.70 -0.54 0.22 -3.77 -4.58 -0.77 -0.80 -3.34 -4.07
6290 || orf19.5144 || PGA28 || || Protein similar to S. cerevisiae Wsc2p, which has roles in stress- and cell-wall-related processes; predicted Kex2p substrate; putative GPI-anchored adhesin-like protein || 1 2.00 1.77 1.99 2.44 -3.43 -3.86 -0.56 -0.21 -0.52 0.01 -3.91 -4.86 -0.17 -1.15 -3.44 -4.80
6291 || orf19.4072 || IFF6 || || Putative GPI-anchored adhesin-like protein; opaque-specific transcript; macrophage-induced gene; Hap43-repressed gene; Spider biofilm induced || 1 1.91 1.78 -4.64 -5.11 -0.39 -0.30 -0.22 0.35 -5.94 -6.37 0.77 -0.81 -4.62 -5.38
6292 || orf19.4072 || IFF6 || || Putative GPI-anchored adhesin-like protein; opaque-specific transcript; macrophage-induced gene; Hap43-repressed gene; Spider biofilm induced || 1 1.71 1.75 1.91 2.37 -4.43 -4.88 -0.58 -0.43 -0.31 0.43 -5.82 -6.27 0.95 -0.60 -4.83 -5.75
6293 || orf19.2460 || || || Protein of unknown function; substrate for Kex2 processing in vitro; repressed by alpha pheromone in SpiderM medium; Spider biofilm induced; Bcr1-repressed in a/a RPMI biofilms || 1 1.78 1.67 1.98 -4.28 -4.47 -0.56 -0.61 0.06 0.63 -6.15 -6.69 0.86 -0.70 -4.90 -5.22
6294 || orf19.7668 || MAL2 || || Alpha-glucosidase; hydrolyzes sucrose for sucrose utilization; transcript regulated by Suc1, induced by maltose, repressed by glucose; Tn mutation affects filamentous growth; upregulated in RHE model; rat catheter and Spider biofilm induced || 1 0.39 0.39 0.51 0.76 -1.13 -1.29 -0.37 -0.03 0.12 0.05 -1.71 -1.62 -0.44 0.04 -1.26 -1.64
6295 || orf19.3444 || || || Predicted membrane transporter, member of the drug:proton antiporter (14 spanner) (DHA2) family, major facilitator superfamily (MFS); Hap43p-repressed gene || 1 0.45 0.51 1.20 0.81 -1.90 -2.59 -0.41 -0.15 0.48 -0.25 -3.09 -4.42 -0.12 -0.44 -3.05 -3.42
6296 || orf19.4884 || WOR1 || || Transcription factor (master switch) of white-opaque phenotypic switching; required to establish and maintain the opaque state; opaque-specific, nuclear; regulates its own expression; suggested role in regulation of adhesion factors || 1 -0.04 -0.03 -0.07 0.37 -6.48 -10.34 0.67 0.31 0.34 0.59 -6.20 -7.62 0.70 0.28 -6.45 -5.25
6297 || orf19.4505 || ADH3 || || Putative NAD-dependent (R,R)-butanediol dehydrogenase; regulated by white-opaque switch; induced by nitric oxide independent of Yhb1; Spider biofilm induced || 1 -0.53 -0.48 0.79 0.64 -4.28 -5.29 0.44 0.43 -0.21 0.71 -5.13 -3.99 -0.65 0.40 -3.65 -4.39
6298 || orf19.4972 || || || Putative transcription factor with zinc finger DNA-binding motif || 1 0.76 0.86 0.38 0.58 -4.69 -4.65 0.87 0.22 0.46 0.51 -5.24 -4.00 0.78 -0.01 -5.18 -4.36
6299 || orf19.4884 || WOR1 || || Transcription factor (master switch) of white-opaque phenotypic switching; required to establish and maintain the opaque state; opaque-specific, nuclear; regulates its own expression; suggested role in regulation of adhesion factors || 1 -0.40 -0.27 -0.17 -0.01 -6.18 -4.93 0.53 0.24 0.43 0.55 -5.88 -5.68 0.51 0.56 -6.43 -5.79
6300 || orf19.4505 || ADH3 || || Putative NAD-dependent (R,R)-butanediol dehydrogenase; regulated by white-opaque switch; induced by nitric oxide independent of Yhb1; Spider biofilm induced || 1 -0.29 -0.50 0.69 0.37 -5.28 -4.90 0.44 0.40 -0.28 0.36 -6.59 -6.15 -0.28 0.58 -6.39 -5.57
6301 || orf19.4505 || ADH3 || || Putative NAD-dependent (R,R)-butanediol dehydrogenase; regulated by white-opaque switch; induced by nitric oxide independent of Yhb1; Spider biofilm induced || 1 -0.04 -0.15 0.51 0.31 -3.35 -4.43 0.76 0.67 -0.22 0.46 -3.93 -5.15 -0.12 0.95 -3.46 -4.40
6302 || orf19.4884 || WOR1 || || Transcription factor (master switch) of white-opaque phenotypic switching; required to establish and maintain the opaque state; opaque-specific, nuclear; regulates its own expression; suggested role in regulation of adhesion factors || 1 -0.08 -0.12 -0.29 0.16 -3.07 -4.62 0.54 0.31 0.53 0.63 -4.71 -5.83 0.66 0.94 -4.02 -4.66
6303 || orf19.4884 || WOR1 || || Transcription factor (master switch) of white-opaque phenotypic switching; required to establish and maintain the opaque state; opaque-specific, nuclear; regulates its own expression; suggested role in regulation of adhesion factors || 1 -0.16 -0.23 -0.25 0.00 -5.30 -5.90 0.63 0.33 0.45 0.50 -4.90 -6.69 0.49 0.41 -5.52 -5.62
6304 || orf19.2833 || PGA34 || || Putative GPI-anchored protein; transcript repressed by alpha pheromone in SpiderM medium; induced in oralpharyngeal candidasis; flow model biofilm induced; Spider biofilm induced || 1 0.07 -0.06 -0.14 0.52 -5.78 -5.95 -0.15 0.02 -0.15 0.70 -6.16 -7.74 0.63 0.39 -5.81 -6.30
6305 || orf19.2833 || PGA34 || || Putative GPI-anchored protein; transcript repressed by alpha pheromone in SpiderM medium; induced in oralpharyngeal candidasis; flow model biofilm induced; Spider biofilm induced || 1 0.02 -0.07 -0.11 0.56 -3.42 -4.49 -0.21 -0.11 -0.25 0.66 -4.17 -5.08 0.74 0.40 -3.38 -4.93
6306 || orf19.2833 || PGA34 || || Putative GPI-anchored protein; transcript repressed by alpha pheromone in SpiderM medium; induced in oralpharyngeal candidasis; flow model biofilm induced; Spider biofilm induced || 1 0.18 0.09 0.01 0.55 -2.29 -3.23 -0.21 -0.15 -0.13 0.49 -3.76 -4.04 0.66 0.23 -3.44 -4.31
6307 || orf19.1313 || CDR3 || || Transporter of the Pdr/Cdr family of the ATP-binding cassette superfamily; transports phospholipids out-to-in; expressed in opaque-phase cells; induced by macrophage interaction; fluconazole-repressed; Spider biofilm induced || 1 -0.22 -0.32 -0.29 0.72 -2.06 -2.88 0.07 0.10 0.14 0.75 -2.68 -3.13 0.00 0.04 -2.43 -2.99
6308 || orf19.1313 || CDR3 || || Transporter of the Pdr/Cdr family of the ATP-binding cassette superfamily; transports phospholipids out-to-in; expressed in opaque-phase cells; induced by macrophage interaction; fluconazole-repressed; Spider biofilm induced || 1 -0.12 -0.20 -0.06 0.80 -1.95 -2.61 0.09 0.40 0.15 0.89 -2.53 -3.05 0.18 -0.07 -2.33 -3.16
6309 || orf19.1313 || CDR3 || || Transporter of the Pdr/Cdr family of the ATP-binding cassette superfamily; transports phospholipids out-to-in; expressed in opaque-phase cells; induced by macrophage interaction; fluconazole-repressed; Spider biofilm induced || 1 -0.18 -0.15 -0.12 0.90 -1.59 -2.61 0.08 0.14 0.08 0.76 -2.21 -3.07 0.13 -0.14 -1.88 -2.98
6310 || orf19.2833 || PGA34 || || Putative GPI-anchored protein; transcript repressed by alpha pheromone in SpiderM medium; induced in oralpharyngeal candidasis; flow model biofilm induced; Spider biofilm induced || 1 0.24 0.07 0.40 0.87 -2.32 -2.70 0.01 0.07 -0.03 0.48 -2.65 -4.43 0.54 0.01 -2.27 -3.10
6311 || orf19.2833 || PGA34 || || Putative GPI-anchored protein; transcript repressed by alpha pheromone in SpiderM medium; induced in oralpharyngeal candidasis; flow model biofilm induced; Spider biofilm induced || 1 0.68 0.46 0.37 0.97 -3.09 -4.86 0.09 0.29 0.02 0.81 -3.08 -5.93 1.12 0.23 -3.99 -4.64
6312 || orf19.4884 || WOR1 || || Transcription factor (master switch) of white-opaque phenotypic switching; required to establish and maintain the opaque state; opaque-specific, nuclear; regulates its own expression; suggested role in regulation of adhesion factors || 1 -0.08 -0.17 0.04 0.26 -2.53 -3.51 0.34 0.04 0.36 0.49 -2.27 -4.47 0.37 0.41 -2.26 -4.17
6313 || orf19.4590 || RFX2 || || Transcriptional repressor; regulator of filamentation, response to DNA damage, adhesion, virulence in murine mucosal, systemic infections; RFX domain; regulated by Nrg1, UV-induced; partially complements S. cerevisiae rfx1 mutant defects || 1 0.62 0.46 -0.71 0.50 -1.41 -2.98 0.49 0.51 0.29 1.13 -2.49 -3.16 -0.08 -0.56 -1.66 -3.02
6314 || orf19.4590 || RFX2 || || Transcriptional repressor; regulator of filamentation, response to DNA damage, adhesion, virulence in murine mucosal, systemic infections; RFX domain; regulated by Nrg1, UV-induced; partially complements S. cerevisiae rfx1 mutant defects || 1 0.78 0.73 -0.18 0.92 -1.83 -3.12 0.74 0.65 0.56 1.33 -3.09 -3.42 -0.34 -0.54 -2.22 -3.77
6315 || orf19.4590 || RFX2 || || Transcriptional repressor; regulator of filamentation, response to DNA damage, adhesion, virulence in murine mucosal, systemic infections; RFX domain; regulated by Nrg1, UV-induced; partially complements S. cerevisiae rfx1 mutant defects || 1 0.44 0.40 -0.39 0.85 -2.15 -2.80 0.37 0.64 0.49 1.17 -2.77 -3.53 -0.49 -0.62 -2.31 -3.06
6316 || orf19.4590 || RFX2 || || Transcriptional repressor; regulator of filamentation, response to DNA damage, adhesion, virulence in murine mucosal, systemic infections; RFX domain; regulated by Nrg1, UV-induced; partially complements S. cerevisiae rfx1 mutant defects || 1 -0.02 -0.08 -1.15 0.44 -3.05 -3.25 0.10 0.20 0.13 1.07 -3.85 -3.89 -0.78 -0.59 -2.88 -3.45
6317 || orf19.2886 || CEK1 || || ERK-family protein kinase; required for wild-type yeast-hypha switch, mating efficiency, virulence in mice; Cst20-Hst7-Cek1-Cph1 MAPK pathway regulates mating, and invasive hyphal growth under some conditions; Spider biofilm induced || 1 -0.05 -0.17 -0.29 -0.24 -2.10 -2.41 -0.01 0.15 -0.01 0.62 -2.53 -2.63 -0.54 -0.70 -1.12 -3.14
6318 || orf19.742 || ALD6 || || Putative aldehyde dehydrogenase; stationary phase enriched protein; expression regulated upon white-opaque switch; rat catheter biofilm induced; rat catheter and Spider biofilm induced || 1 0.56 0.56 1.18 0.82 -2.02 -2.76 0.50 0.77 -0.63 1.23 -4.61 -4.76 0.68 0.15 -2.72 -4.45
6319 || orf19.742 || ALD6 || || Putative aldehyde dehydrogenase; stationary phase enriched protein; expression regulated upon white-opaque switch; rat catheter biofilm induced; rat catheter and Spider biofilm induced || 1 0.04 0.10 0.81 0.65 -2.61 -3.30 -0.20 0.12 -1.00 1.26 -4.48 -5.05 0.56 0.14 -3.14 -3.68
6320 || orf19.4505 || ADH3 || || Putative NAD-dependent (R,R)-butanediol dehydrogenase; regulated by white-opaque switch; induced by nitric oxide independent of Yhb1; Spider biofilm induced || 1 -0.08 -0.25 0.63 0.38 -1.76 -1.83 0.41 0.06 -0.55 -0.00 -4.71 -3.51 -0.20 0.25 -2.80 -3.12
6321 || orf19.6854 || ATP1 || || ATP synthase alpha subunit; antigenic in human/mouse; at hyphal surface; ciclopirox, ketoconazole, flucytosine induced; Efg1, caspofungin repressed; may be essential; sumoylation target; stationary phase-enriched; Spider biofilm repressed || 1 -0.18 -0.23 -0.03 0.04 -1.42 -1.17 0.24 -0.01 0.09 -0.25 -1.41 -1.21 -0.03 0.14 -1.29 -0.54
6322 || orf19.3223 || ATP3 || || F1-ATP synthase complex subunit; caspofungin repressed; flucytosine and macrophage/pseudohyphal-induced; present in exponential and stationary growth phases; Hap43p-induced gene || 1 0.10 -0.00 -0.21 -0.08 -1.01 -1.01 0.13 0.07 0.12 -0.12 -1.24 -1.23 0.00 0.50 -1.14 -0.80
6323 || orf19.3223 || ATP3 || || F1-ATP synthase complex subunit; caspofungin repressed; flucytosine and macrophage/pseudohyphal-induced; present in exponential and stationary growth phases; Hap43p-induced gene || 1 0.27 0.21 -0.03 0.24 -0.86 -0.94 0.16 0.14 0.27 -0.01 -1.16 -0.97 0.07 0.49 -1.04 -0.91
6324 || orf19.6854 || ATP1 || || ATP synthase alpha subunit; antigenic in human/mouse; at hyphal surface; ciclopirox, ketoconazole, flucytosine induced; Efg1, caspofungin repressed; may be essential; sumoylation target; stationary phase-enriched; Spider biofilm repressed || 1 0.07 -0.02 0.23 0.33 -1.22 -1.11 0.26 0.14 0.38 -0.01 -1.24 -1.11 0.25 0.26 -1.28 -0.73
6325 || orf19.4361 || IFF3 || || Putative GPI-anchored protein || 1 0.06 -0.27 0.82 0.87 -1.87 -2.15 0.17 -0.09 0.57 -0.00 -1.87 -1.75 -0.36 0.10 -2.09 -1.65
6326 || orf19.857 || FMO2 || || Protein with a monooxygenase domain; Spider biofilm induced || 1 -0.52 -0.63 0.81 0.79 -3.04 -2.33 0.68 -0.21 0.70 0.08 -2.66 -1.91 -0.23 -0.06 -2.11 -1.43
6327 || orf19.5265 || KIP4 || || S. cerevisiae Smy1 ortholog; Tn mutation affects filamentous growth; filament induced; has Mob2-dependent hyphal regulation; regulated by Nrg1, Tup1; oralpharyngeal candidasis induced; Spider biofilm induced; flow model biofilm repressed || 1 -0.38 -0.40 -0.51 0.25 -3.26 -3.06 0.16 -0.34 0.53 0.44 -2.52 -2.33 -0.03 -0.37 -3.18 -1.89
6328 || orf19.5265 || KIP4 || || S. cerevisiae Smy1 ortholog; Tn mutation affects filamentous growth; filament induced; has Mob2-dependent hyphal regulation; regulated by Nrg1, Tup1; oralpharyngeal candidasis induced; Spider biofilm induced; flow model biofilm repressed || 1 0.05 -0.05 -0.21 0.70 -2.41 -2.16 0.24 -0.22 1.00 0.75 -1.66 -1.53 -0.02 -0.11 -1.88 -1.20
6329 || orf19.4505 || ADH3 || || Putative NAD-dependent (R,R)-butanediol dehydrogenase; regulated by white-opaque switch; induced by nitric oxide independent of Yhb1; Spider biofilm induced || 1 0.17 0.07 1.09 0.72 -2.34 -3.26 0.67 0.67 0.06 0.58 -2.02 -3.42 0.10 1.11 -2.08 -2.64
6330 || orf19.6570 || NUP || || Nucleoside permease; adenosine and guanosine are substrates, whereas cytidine, adenine, guanine, uridine, uracil are not; similar to a nucleoside permease of S. pombe; possibly processed by Kex2p || 1 0.34 0.26 0.78 1.12 -1.70 -3.31 0.49 0.78 0.44 0.70 -1.72 -2.08 -0.23 0.31 -1.83 -1.30
6331 || orf19.6570 || NUP || || Nucleoside permease; adenosine and guanosine are substrates, whereas cytidine, adenine, guanine, uridine, uracil are not; similar to a nucleoside permease of S. pombe; possibly processed by Kex2p || 1 0.16 0.52 0.75 1.01 -1.17 -2.49 0.47 0.70 0.68 0.51 -1.06 -1.76 0.02 0.23 -1.41 -1.55
6332 || orf19.857 || FMO2 || || Protein with a monooxygenase domain; Spider biofilm induced || 1 0.38 0.15 0.30 0.82 -1.14 -2.68 0.40 0.56 0.76 0.53 -0.89 -2.55 0.04 0.54 -1.07 -1.06
6333 || orf19.1330 || || || Ortholog of Candida albicans WO-1 : CAWG_05678 || 1 0.32 0.30 0.17 0.41 -0.41 -1.12 0.40 0.29 0.95 0.24 -1.66 -1.14 0.25 0.23 -0.22 -1.48
6334 || orf19.6703 || || || Ortholog of C. dubliniensis CD36 : Cd36_73260 and Candida albicans WO-1 : CAWG_05699 || 1 0.10 -0.05 0.18 0.01 -1.00 -1.05 0.43 0.01 0.67 0.52 -1.77 -1.00 0.34 0.42 -0.54 -0.92
6335 || orf19.1330 || || || Ortholog of Candida albicans WO-1 : CAWG_05678 || 1 -0.04 -0.06 -0.21 0.14 -0.84 -0.83 0.43 -0.00 0.80 0.12 -1.82 -1.05 0.28 0.45 -0.46 -1.33
6336 || orf19.6703 || || || Ortholog of C. dubliniensis CD36 : Cd36_73260 and Candida albicans WO-1 : CAWG_05699 || 1 0.08 -0.17 0.06 0.25 -1.09 -1.03 0.06 -0.08 0.34 0.01 -2.02 -1.29 0.20 -0.21 -0.67 -1.18
6337 || orf19.6025 || || || Ortholog(s) have N-acetylglucosaminyldiphosphodolichol N-acetylglucosaminyltransferase activity and role in dolichol-linked oligosaccharide biosynthetic process || 1 0.46 0.60 -0.11 -0.20 -0.75 -1.35 -0.04 0.41 0.46 0.23 -0.93 -0.74 0.43 0.46 -1.16 -1.01
6338 || orf19.6277 || || || Has domain(s) with predicted phosphatidylinositol binding activity and role in cell communication || 1 1.37 1.20 -0.37 0.15 -1.59 -3.48 0.75 1.00 0.42 0.59 -1.82 -1.69 0.94 0.33 -1.64 -1.98
6339 || orf19.2066.1 || ATP18 || || F1F0 ATP synthase complex subunit; gene has intron || 1 0.37 0.38 -0.26 -0.22 -0.83 -0.97 0.53 0.48 0.07 0.04 -0.58 -0.78 -0.36 0.20 -0.83 -0.57
6340 || orf19.2066.1 || ATP18 || || F1F0 ATP synthase complex subunit; gene has intron || 1 0.28 0.18 -0.26 -0.12 -0.94 -0.89 0.67 0.51 0.03 0.29 -0.67 -0.76 -0.05 0.25 -0.84 -0.55
6341 || orf19.3579 || ATP4 || || Putative F0-ATP synthase subunit 4; macrophage/pseudohyphal-induced; present in exponential and stationary growth phases || 1 0.28 0.19 -0.39 -0.37 -1.06 -1.20 0.49 0.44 -0.15 -0.03 -0.90 -1.13 -0.04 0.23 -1.03 -0.59
6342 || orf19.3579 || ATP4 || || Putative F0-ATP synthase subunit 4; macrophage/pseudohyphal-induced; present in exponential and stationary growth phases || 1 0.39 0.37 -0.37 -0.35 -1.08 -1.08 0.41 0.32 -0.13 0.01 -0.89 -1.14 0.08 0.25 -1.05 -0.73
6343 || orf19.5419 || ATP5 || || Putative F0-ATP synthase FO subunit B; caspofungin repressed; protein level decreased in stationary phase yeast cultures; Spider biofilm repressed || 1 0.37 0.41 -0.10 0.21 -1.04 -1.05 0.56 0.49 0.34 0.08 -0.81 -1.09 0.36 0.26 -1.10 -0.55
6344 || orf19.5181 || NIK1 || || Histidine kinase involved in a two-component signaling pathway that regulates cell wall biosynthesis; required for wild-type virulence in mouse systemic infection but not for wild-type growth or drug sensitivity/resistance; 9 HAMP domains || 1 0.33 0.35 -0.04 0.05 -0.70 -0.86 0.21 0.23 0.08 -0.18 -0.35 -0.55 0.39 0.02 -0.68 -0.82
6345 || orf19.3579 || ATP4 || || Putative F0-ATP synthase subunit 4; macrophage/pseudohyphal-induced; present in exponential and stationary growth phases || 1 0.68 0.59 0.04 0.14 -1.07 -1.56 0.52 0.63 0.01 -0.22 -1.00 -1.50 0.25 -0.45 -1.26 -1.22
6346 || orf19.1467 || COX13 || || Cytochrome c oxidase; flucytosine induced; repressed by nitric oxide || 1 0.55 0.46 0.17 -0.25 -0.73 -0.96 0.55 0.50 0.11 -0.17 -0.79 -1.06 0.17 0.22 -0.75 -0.71
6347 || orf19.1467 || COX13 || || Cytochrome c oxidase; flucytosine induced; repressed by nitric oxide || 1 0.41 0.28 0.03 -0.16 -0.59 -0.60 0.47 0.56 0.06 -0.31 -0.49 -0.72 -0.02 0.06 -0.62 -0.51
6348 || orf19.3579 || ATP4 || || Putative F0-ATP synthase subunit 4; macrophage/pseudohyphal-induced; present in exponential and stationary growth phases || 1 0.56 0.44 0.13 -0.12 -0.90 -0.98 0.74 0.68 0.03 0.13 -0.63 -0.84 0.32 0.45 -0.97 -0.57
6349 || orf19.2066.1 || ATP18 || || F1F0 ATP synthase complex subunit; gene has intron || 1 0.43 0.46 -0.15 -0.07 -0.74 -0.70 0.75 0.62 0.28 0.35 -0.53 -0.51 -0.04 0.25 -0.68 -0.48
6350 || orf19.2066.1 || ATP18 || || F1F0 ATP synthase complex subunit; gene has intron || 1 0.58 0.51 -0.12 -0.06 -0.75 -0.78 0.70 0.62 0.24 0.29 -0.65 -0.49 0.17 0.47 -0.75 -0.38
6351 || orf19.2066.1 || ATP18 || || F1F0 ATP synthase complex subunit; gene has intron || 1 0.34 0.38 -0.12 0.00 -0.87 -0.78 0.63 0.52 0.29 0.30 -0.51 -0.48 0.09 0.54 -0.61 -0.25
6352 || orf19.4612 || || || Protein with a dienelactone hydrolase domain; Hap43-repressed gene || 1 0.87 0.88 0.98 0.05 -2.68 -2.12 0.47 0.36 1.22 -0.15 -3.45 -3.50 -1.55 0.15 -4.17 -2.30
6353 || orf19.4612 || || || Protein with a dienelactone hydrolase domain; Hap43-repressed gene || 1 0.93 0.83 0.97 0.00 -2.78 -2.20 0.61 0.24 1.24 -0.19 -3.32 -3.73 -1.59 0.11 -4.40 -2.33
6354 || orf19.5933 || || || Protein of unknown function; transcript induced by benomyl treatment || 1 0.42 0.26 0.97 -0.22 -0.37 -1.81 1.32 0.33 0.87 0.72 -2.00 -2.13 1.47 0.22 -1.83 -3.74
6355 || orf19.4069 || || || Protein of unknown function; repressed by alpha pheromone in SpiderM medium || 1 0.23 0.41 1.08 1.24 -0.24 -1.51 -0.06 0.16 0.54 1.06 -0.58 -2.09 0.25 1.00 -0.69 -1.94
6356 || orf19.4069 || || || Protein of unknown function; repressed by alpha pheromone in SpiderM medium || 1 0.38 0.27 1.09 1.22 -0.62 -1.87 -0.06 0.58 0.46 1.27 -1.14 -2.06 0.31 0.75 -1.09 -1.72
6357 || orf19.4069 || || || Protein of unknown function; repressed by alpha pheromone in SpiderM medium || 1 0.80 0.58 1.49 1.12 -0.85 -1.30 0.43 0.45 0.58 1.00 -1.38 -1.59 0.37 0.73 -0.85 -2.17
6358 || orf19.1701 || RKI1 || || Ortholog(s) have ribose-5-phosphate isomerase activity, role in pentose-phosphate shunt, pyridoxine biosynthetic process and cytoplasm, nucleus localization || 1 0.66 0.66 0.96 1.11 -0.38 -1.26 0.30 0.78 0.59 0.67 -0.82 -1.21 0.11 0.38 -0.53 -1.03
6359 || orf19.3311 || IFD3 || || Putative aldo/keto reductase; Mig1-regulated || 1 0.37 0.31 0.73 0.95 -0.24 -0.66 0.27 0.40 0.61 0.54 -0.62 -0.77 -0.21 -0.08 -0.43 -0.86
6360 || orf19.5140 || || || Protein of unknown function; rat catheter and Spider biofilm induced || 1 0.56 0.70 0.95 1.35 -0.49 -0.86 0.22 0.06 0.96 0.62 -1.88 -2.22 0.39 -0.47 -0.94 -2.07
6361 || orf19.4070 || || || Ortholog of C. dubliniensis CD36 : Cd36_23270 || 1 0.26 0.51 0.55 0.67 -0.06 -0.75 -0.22 0.24 0.82 0.32 -0.84 -1.18 0.39 -0.15 -0.60 -1.24
6362 || orf19.1721 || NCE103 || || Carbonic anhydrase; converts of CO2 to bicarbonate; essential for virulence in host niches with limited CO2, normal white-opaque switch; Mnl1-induced in weak acid stress; Hap43-induced gene; F-12/CO2, rat catheter, Spider biofilm induced || 1 0.48 0.80 0.81 0.78 -0.03 -1.00 -0.24 -0.17 0.30 1.03 -0.93 -1.87 0.37 0.06 -0.50 -1.92
6363 || orf19.2457 || || || Protein of unknown function; induced during chlamydospore formation in both C. albicans and C. dubliniensis; Spider biofilm induced || 1 1.96 1.75 0.91 1.10 -0.01 -2.10 0.46 0.11 0.90 1.49 -1.84 -2.54 0.74 -0.48 -1.43 -3.12
6364 || orf19.742 || ALD6 || || Putative aldehyde dehydrogenase; stationary phase enriched protein; expression regulated upon white-opaque switch; rat catheter biofilm induced; rat catheter and Spider biofilm induced || 1 0.85 0.72 1.05 0.88 -0.31 -1.04 0.16 0.31 -0.08 1.16 -1.12 -2.36 0.79 0.06 -0.94 -1.12
6365 || orf19.742 || ALD6 || || Putative aldehyde dehydrogenase; stationary phase enriched protein; expression regulated upon white-opaque switch; rat catheter biofilm induced; rat catheter and Spider biofilm induced || 1 1.03 0.59 1.16 0.82 -1.14 -1.26 0.39 0.43 0.04 1.10 -2.21 -2.86 0.66 -0.16 -0.95 -2.38
6366 || orf19.742 || ALD6 || || Putative aldehyde dehydrogenase; stationary phase enriched protein; expression regulated upon white-opaque switch; rat catheter biofilm induced; rat catheter and Spider biofilm induced || 1 0.65 0.49 1.07 0.84 -1.12 -2.07 0.00 0.45 -0.65 1.29 -2.23 -3.52 0.77 -0.30 -1.44 -2.91
6367 || orf19.2886 || CEK1 || || ERK-family protein kinase; required for wild-type yeast-hypha switch, mating efficiency, virulence in mice; Cst20-Hst7-Cek1-Cph1 MAPK pathway regulates mating, and invasive hyphal growth under some conditions; Spider biofilm induced || 1 0.66 0.63 0.70 0.56 -1.57 -2.28 0.64 0.76 1.09 1.35 -2.17 -2.35 0.27 -0.58 -0.60 -2.58
6368 || orf19.4590 || RFX2 || || Transcriptional repressor; regulator of filamentation, response to DNA damage, adhesion, virulence in murine mucosal, systemic infections; RFX domain; regulated by Nrg1, UV-induced; partially complements S. cerevisiae rfx1 mutant defects || 1 0.75 0.82 0.18 0.92 -0.47 -1.75 0.51 0.60 0.70 1.32 -1.11 -2.01 0.22 -0.11 -0.60 -1.75
6369 || orf19.5302 || PGA31 || || Cell wall protein; putative GPI anchor; expression regulated upon white-opaque switch; induced by Congo Red and cell wall regeneration; Bcr1-repressed in RPMI a/a biofilms || 1 0.73 0.75 0.41 1.47 -0.31 -2.18 -0.57 -0.06 -0.08 0.54 -1.58 -2.80 -0.17 -0.30 -1.38 -2.17
6370 || orf19.7130 || || || Protein of unknown function; Hap43-repressed gene || 1 0.48 0.39 0.37 0.28 -0.48 -1.07 0.46 0.28 0.77 0.14 -0.83 -1.04 -0.17 -0.15 -0.75 -0.98
6371 || orf19.799 || STE4 || || Beta subunit of heterotrimeric G protein of mating signal transduction pathway; required for mating; transcript is specific to cells homozygous at MTL; induced by alpha pheromone; ortholog of S. cerevisiae Ste4 || 1 0.49 0.32 0.17 0.41 -0.12 0.01 0.43 0.25 0.44 0.41 -1.17 -0.70 0.06 0.31 -0.29 -1.01
6372 || orf19.799 || STE4 || || Beta subunit of heterotrimeric G protein of mating signal transduction pathway; required for mating; transcript is specific to cells homozygous at MTL; induced by alpha pheromone; ortholog of S. cerevisiae Ste4 || 1 0.34 0.42 0.27 0.62 -0.36 -0.14 0.20 0.13 0.29 0.31 -1.27 -0.87 0.07 -0.03 -0.22 -1.22
6373 || orf19.4567 || || || Catechol 1,2-dioxygenase (1,2-CTD), involved in degradation of aromatic compounds; Spider biofilm induced || 1 0.17 0.46 0.68 1.00 -0.47 0.08 0.48 0.10 1.31 0.59 -1.69 -1.26 0.12 0.11 -0.35 -2.40
6374 || orf19.4894 || || || Protein with similarity to S. cerevisiae Yer010cp, a protein of unknown function belonging to the prokaryotic RraA family; repressed by benomyl; Hap43-induced; Spider biofilm induced || 1 0.21 0.15 0.42 0.59 -0.22 -0.12 -0.10 -0.12 0.74 0.16 -1.22 -0.84 -0.05 0.51 0.08 -2.16
6375 || orf19.3612 || PST2 || || Putative NADH:quinone oxidoreductase; similar to 1,4-benzoquinone reductase; immunogenic in mice; induced by benomyl, oxidative stress via Cap1; fungal-specific; farnesol-repressed; Spider biofilm induced || 1 -0.02 -0.09 0.88 0.90 -1.03 -0.27 -0.10 -0.08 0.59 -0.10 -2.52 -2.27 0.12 0.23 -0.25 -3.21
6376 || orf19.3612 || PST2 || || Putative NADH:quinone oxidoreductase; similar to 1,4-benzoquinone reductase; immunogenic in mice; induced by benomyl, oxidative stress via Cap1; fungal-specific; farnesol-repressed; Spider biofilm induced || 1 -0.00 -0.14 0.90 0.53 -1.50 -0.82 0.01 0.03 0.30 -0.29 -2.37 -2.06 0.30 0.40 -0.60 -2.71
6377 || orf19.3612 || PST2 || || Putative NADH:quinone oxidoreductase; similar to 1,4-benzoquinone reductase; immunogenic in mice; induced by benomyl, oxidative stress via Cap1; fungal-specific; farnesol-repressed; Spider biofilm induced || 1 0.18 0.25 0.65 0.92 -1.39 -0.91 0.39 0.41 0.50 -0.19 -2.31 -2.12 0.33 -0.01 -0.52 -2.97
6378 || orf19.3612 || PST2 || || Putative NADH:quinone oxidoreductase; similar to 1,4-benzoquinone reductase; immunogenic in mice; induced by benomyl, oxidative stress via Cap1; fungal-specific; farnesol-repressed; Spider biofilm induced || 1 0.70 0.48 1.25 1.32 -1.29 -0.63 0.34 0.56 0.64 -0.07 -2.20 -1.97 0.33 0.34 -0.41 -2.48
6379 || orf19.1599 || || || Ortholog of Candida albicans WO-1 : CAWG_06018 || 1 -0.32 -0.32 0.49 0.78 -1.10 -0.78 0.19 -0.06 1.37 0.87 -1.46 -1.51 0.83 -0.20 -1.22 -2.38
6380 || orf19.1599 || || || Ortholog of Candida albicans WO-1 : CAWG_06018 || 1 0.08 -0.38 0.48 0.72 -0.62 -0.49 0.19 -0.10 1.12 0.37 -1.58 -1.29 0.45 0.12 -0.45 -1.51
6381 || orf19.1599 || || || Ortholog of Candida albicans WO-1 : CAWG_06018 || 1 -0.14 -0.04 0.69 0.67 -0.51 -0.59 0.11 -0.22 1.41 0.38 -1.24 0.71 -0.09 -0.61 -1.15
6382 || orf19.3212 || MID1 || || Putative stretch-activated Ca2+ channel of the high affinity calcium uptake system; role in thigmotropism; decreased transcription is observed upon fluphenazine treatment or in an azole-resistant strain with CDR1 and CDR2 overexpression || 1 -0.31 -0.39 -0.03 -0.04 -0.46 -0.55 -0.15 -0.46 0.50 0.16 -1.08 -0.72 -0.04 0.31 -0.62 -0.47
6383 || orf19.7316 || || || Putative phytanoyl-CoA dioxygenase family protein; mutation confers hypersensitivity to 5-fluorocytosine (5-FC), 5-fluorouracil (5-FU), and tubercidin (7-deazaadenosine); induced by nitric oxide || 1 -0.48 -0.49 0.05 0.04 -0.38 -0.39 -0.18 -0.14 -0.01 0.17 -1.30 -0.94 -0.21 -0.11 -0.83 -0.44
6384 || orf19.4384 || HXT5 || || Putative sugar transporter; induced by ciclopirox olamine; Snf3-induced; alkaline repressed; colony morphology-related gene regulation by Ssn6; possibly essential gene || 1 -1.03 -1.04 -0.53 -0.44 -1.89 -0.81 -0.84 -0.09 -0.10 0.94 -2.84 -2.21 -0.25 -0.43 -0.14 -2.07
6385 || orf19.3829 || PHR1 || || Cell surface glycosidase; may act on cell-wall beta-1,3-glucan prior to beta-1,6-glucan linkage; role in systemic, not vaginal virulence (neutral, not low pH); high pH or filamentation induced; Bcr1-repressed in RPMI a/a biofilm || 1 -0.82 -1.18 -0.43 -0.23 -1.12 -1.13 -0.23 -0.61 -0.05 0.79 -2.05 -2.02 -1.06 -0.97 -0.97 -2.00
6386 || orf19.3829 || PHR1 || || Cell surface glycosidase; may act on cell-wall beta-1,3-glucan prior to beta-1,6-glucan linkage; role in systemic, not vaginal virulence (neutral, not low pH); high pH or filamentation induced; Bcr1-repressed in RPMI a/a biofilm || 1 -0.52 -0.66 -0.67 -0.33 -0.84 -1.34 -0.15 -0.52 0.10 0.90 -2.01 -2.08 -0.84 -0.87 -0.72 -2.30
6387 || orf19.1600 || || || Ortholog of C. dubliniensis CD36 : Cd36_23530, C. parapsilosis CDC317 : CPAR2_406140, Candida tenuis NRRL Y-1498 : CANTEDRAFT_116829 and Debaryomyces hansenii CBS767 : DEHA2B01826g || 1 -0.25 -0.30 -0.47 0.01 -0.50 -0.81 0.10 -0.46 0.44 0.05 -1.50 -1.22 0.14 -0.47 -0.79 -1.48
6388 || orf19.1600 || || || Ortholog of C. dubliniensis CD36 : Cd36_23530, C. parapsilosis CDC317 : CPAR2_406140, Candida tenuis NRRL Y-1498 : CANTEDRAFT_116829 and Debaryomyces hansenii CBS767 : DEHA2B01826g || 1 -0.32 -0.44 -0.37 0.14 -0.69 -0.61 0.28 -0.21 0.60 0.35 -1.44 -0.72 0.14 -0.22 -0.70 -1.34
6389 || orf19.4608 || PDC12 || || Putative pyruvate decarboxylase; fungal-specific (no human or murine homolog) || 1 -1.39 -1.37 -0.97 -0.78 -1.05 -1.74 -0.11 0.20 0.84 0.45 -3.50 -2.31 -0.10 0.30 -2.12 -3.49
6390 || orf19.4608 || PDC12 || || Putative pyruvate decarboxylase; fungal-specific (no human or murine homolog) || 1 -0.75 -0.90 -0.32 -0.63 -0.88 -1.34 0.28 0.16 0.93 0.33 -2.45 -2.52 -0.13 0.59 -1.23 -2.13
6391 || orf19.5113 || ADH2 || || Alcohol dehydrogenase; soluble in hyphae; expression regulated by white-opaque switching; regulated by Ssn6; indued by Mnl1 in weak acid stress; protein enriched in stationary phase yeast cultures; Spider biofilm induced || 1 -0.59 -1.46 -1.43 -0.00 -0.38 1.03 -0.05 -4.23 -4.59 0.13 0.08 -3.27 -4.01
6392 || orf19.4608 || PDC12 || || Putative pyruvate decarboxylase; fungal-specific (no human or murine homolog) || 1 -1.14 -1.39 -0.98 -0.81 -1.28 -0.72 0.13 -0.23 0.36 0.33 -2.85 -2.83 -0.60 0.17 -1.45 -1.91
6393 || orf19.4608 || PDC12 || || Putative pyruvate decarboxylase; fungal-specific (no human or murine homolog) || 1 -0.70 -0.44 -0.44 -0.91 -0.72 -1.13 -0.22 -0.33 0.76 0.10 -1.68 -2.37 0.48 0.29 -1.53 -1.37
6394 || orf19.7314 || CDG1 || || Putative cysteine dioxygenases; role in conversion of cysteine to sulfite; transcript regulated upon white-opaque switch; rat catheter, Spider and flow model biofilm induced || 1 1.01 0.96 0.20 -0.08 -0.01 0.56 -0.15 -0.58 0.94 -0.19 -4.34 -3.38 -0.37 -0.27 -3.42 -3.12
6395 || orf19.7314 || CDG1 || || Putative cysteine dioxygenases; role in conversion of cysteine to sulfite; transcript regulated upon white-opaque switch; rat catheter, Spider and flow model biofilm induced || 1 0.62 0.57 -0.01 -0.64 -0.17 0.43 -0.17 -0.83 0.77 -0.29 -4.65 -3.36 -0.64 -0.12 -3.78 -2.41
6396 || orf19.5061 || ADE5,7 || || Phosphoribosylamine-glycine ligase and phosphoribosylformylglycinamidine cyclo-ligase; interacts with Vps34p; required for hyphal growth and virulence; flucytosine induced; not induced in GCN response, in contrast to S. cerevisiae ortholog || 1 0.42 0.52 -0.04 -0.30 -0.56 -0.32 -0.61 -0.23 -0.71 -0.29 -1.13 -1.45 -0.65 -0.01 -1.41 -0.43
6397 || orf19.5021 || PDX1 || || Pyruvate dehydrogenase complex protein X; essential component of the mitochondrial pyruvate dehydrogenase complex; role in the respiratory pathway; protein present in exponential and stationary growth phase yeast; Spider biofilm repressed || 1 0.46 0.46 0.02 -0.16 -0.42 -0.39 -0.43 0.05 -0.49 -0.15 -1.06 -1.16 -0.19 0.01 -1.31 -0.61
6398 || orf19.3097 || PDA1 || || Putative pyruvate dehydrogenase alpha chain; fluconazole-induced; protein present in exponential and stationary growth phase yeast cultures; Hap43-induced; Spider biofilm repressed || 1 0.38 0.34 0.02 0.08 -0.64 -0.49 -0.24 -0.21 -0.32 -0.40 -0.79 -0.83 -0.30 -0.21 -0.95 -0.60
6399 || orf19.4015 || CAG1 || || heterotrimeric G protein alpha subunit; positive role in mating pheromone response; opaque-enriched transcript; transcript repressed by MTLa1-MTLalpha2; regulated by hemoglobin-responsive Hbr1 via MTL genes; rat catheter biofilm repressed || 1 0.28 0.18 0.02 0.05 -0.77 -0.73 -0.20 -0.27 -0.56 -0.44 -0.93 -1.29 -0.52 -0.12 -0.80 -0.64
6400 || orf19.1860 || LSC2 || || Putative succinate-CoA ligase beta subunit; regulated by Mig1, Tup1; induced in high iron; protein present in exponential and stationary growth phase yeast cells; Spider biofilm repressed || 1 0.50 0.44 0.43 0.48 -0.83 -0.96 -0.38 -0.07 -0.69 -0.34 -1.94 -2.43 -0.53 -0.54 -2.64 -2.09
6401 || orf19.4749 || || || Protein of unknown function; hyphal-induced expression, regulated by Cyr1, Ras1, Efg1; Hap43-induced gene; Spider biofilm induced || 1 0.07 0.00 -0.17 0.32 -0.66 -0.50 -0.51 -0.44 -0.37 0.10 -1.14 -0.98 -0.08 -0.19 -0.85 -0.94
6402 || orf19.6165 || KGD1 || || Putative 2-oxoglutarate dehydrogenase; regulated by Efg1 under yeast but not hyphal growth conditions; transcript induced in an RHE model of oral candidiasis; stationary phase enriched protein; Hap43-repressed; rat catheter biofilm induced || 1 0.09 -0.12 0.04 0.25 -0.89 -0.37 -0.36 -0.34 -0.46 0.19 -1.49 -1.56 -1.05 -0.36 -1.40 -1.31
6403 || orf19.6165 || KGD1 || || Putative 2-oxoglutarate dehydrogenase; regulated by Efg1 under yeast but not hyphal growth conditions; transcript induced in an RHE model of oral candidiasis; stationary phase enriched protein; Hap43-repressed; rat catheter biofilm induced || 1 0.07 0.09 0.01 0.16 -0.87 -0.48 -0.24 -0.14 -0.38 0.23 -1.59 -1.59 -0.89 -0.16 -1.30 -1.04
6404 || orf19.4826 || IDH1 || || Putative mitochondrial NAD-isocitrate dehydrogenase subunit 1; soluble protein in hyphae; protein level decrease in stationary phase cultures || 1 0.15 0.06 0.03 0.00 -0.34 -0.58 -0.32 -0.27 -0.38 -0.15 -1.23 -1.23 -0.09 0.07 -1.28 -0.63
6405 || orf19.5791 || IDH2 || || Putative mitochondrial NAD-isocitrate dehydrogenase subunit; induced by ciclopirox; induced in high iron; present in exponential and stationary growth phases; Spider biofilm repressed || 1 -0.10 -0.16 -0.12 -0.17 -0.74 -0.73 -0.25 -0.16 -0.35 -0.13 -1.50 -1.52 -0.26 0.14 -1.51 -0.91
6406 || orf19.4975 || HYR1 || || GPI-anchored hyphal cell wall protein; macrophage-induced; repressed by neutrophils; resistance to killing by neutrophils, azoles; regulated by Rfg1, Efg1, Nrg1, Tup1, Cyr1, Bcr1, Hap43; Spider and flow model biofilm induced || 1 -0.36 -0.49 0.01 -0.47 -1.49 -1.53 -1.12 -1.36 0.15 -0.30 -2.92 -2.97 -0.99 -0.10 -2.21 -1.69
6407 || orf19.3180 || || || Ortholog(s) have phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity, role in phosphatidylinositol dephosphorylation and endoplasmic reticulum localization || 1 0.00 -0.10 0.16 -0.14 -0.71 -0.32 -0.40 -0.50 -0.06 -0.56 -1.16 -1.21 -0.52 -0.27 -0.95 -0.88
6408 || orf19.3363 || VTC4 || || Putative polyphosphate synthetase; decreased expression in hyphae compared to yeast-form cells; fungal-specific (no human or murine homolog); virulence-group-correlated expression || 1 -0.17 -0.28 -0.33 -0.37 -0.52 -0.61 -0.66 -0.58 -0.58 -0.69 -1.73 -1.45 -0.54 0.14 -1.27 -1.32
6409 || orf19.799 || STE4 || || Beta subunit of heterotrimeric G protein of mating signal transduction pathway; required for mating; transcript is specific to cells homozygous at MTL; induced by alpha pheromone; ortholog of S. cerevisiae Ste4 || 1 -0.13 -0.14 -0.60 -0.49 -0.99 -0.92 -0.31 -0.40 -0.43 -0.25 -2.17 -1.81 -0.73 -0.55 -1.10 -1.63
6410 || orf19.799 || STE4 || || Beta subunit of heterotrimeric G protein of mating signal transduction pathway; required for mating; transcript is specific to cells homozygous at MTL; induced by alpha pheromone; ortholog of S. cerevisiae Ste4 || 1 -0.06 0.07 -0.48 -0.13 -0.94 -1.03 -0.08 -0.30 -0.33 -0.28 -1.96 -1.58 -0.51 -0.55 -1.04 -1.77
6411 || orf19.4894 || || || Protein with similarity to S. cerevisiae Yer010cp, a protein of unknown function belonging to the prokaryotic RraA family; repressed by benomyl; Hap43-induced; Spider biofilm induced || 1 0.18 0.17 0.06 0.00 -0.87 -0.66 -0.09 -0.53 0.20 -0.56 -1.76 -2.12 -0.55 0.19 -0.39 -1.48
6412 || orf19.4894 || || || Protein with similarity to S. cerevisiae Yer010cp, a protein of unknown function belonging to the prokaryotic RraA family; repressed by benomyl; Hap43-induced; Spider biofilm induced || 1 -0.02 -0.06 0.11 0.46 -0.94 -0.57 -0.18 -0.53 0.23 -0.46 -2.11 -1.58 -0.56 -0.09 -0.57 -1.69
6413 || orf19.2812 || || || Protein of unknown function; Spider biofilm induced || 1 -0.13 -0.11 0.72 0.60 -0.41 0.08 -0.46 -0.76 0.32 -0.32 -1.31 -1.66 -0.29 -0.22 -0.66 -1.62
6414 || orf19.2812 || || || Protein of unknown function; Spider biofilm induced || 1 -0.58 -0.61 0.48 0.28 -0.85 0.11 -0.55 -0.86 0.35 -0.15 -1.67 -0.56 -1.02 -0.44 -0.82 -1.62
6415 || orf19.2812 || || || Protein of unknown function; Spider biofilm induced || 1 -0.50 -0.52 0.52 0.32 -0.73 -0.04 -0.66 -0.85 0.23 -0.40 -1.96 -1.38 -0.61 -0.27 -0.92 -1.73
6416 || orf19.4655 || OPT6 || || Putative oligopeptide transporter; fungal-specific (no human or murine homolog); expression of OPT6, OPT7, or OPT8 does not suppress defect of mutant lacking Opt1p, Opt2p, and Opt3p; alleles are nonidentical || 1 -0.28 -0.35 0.52 0.31 -0.64 -0.22 -0.42 -0.62 0.31 -0.16 -1.79 -1.21 -0.12 -0.10 -0.45 -0.74
6417 || orf19.3122 || ARR3 || || Ortholog of S. cerevisiae Arr3; arsenite transporter of the plasma membrane required for resistance to arsenic compounds; benomyl-induced; Gcn4-regulated; Hap43-repressed; mutant is viable; Spider biofilm induced || 1 -0.34 -0.33 0.47 0.16 -1.07 -0.35 -0.01 -0.90 0.02 -0.44 -2.15 -1.24 -0.05 -0.08 -1.03 -0.80
6418 || orf19.1596 || FGR28 || || Protein lacking an ortholog in S. cerevisiae; transposon mutation affects filamentous growth; possibly an essential gene, disruptants not obtained by UAU1 method || 1 -0.16 0.07 0.35 0.41 -0.46 -0.17 -0.20 -0.49 0.08 -0.26 -1.33 -0.79 -0.32 0.12 -0.61 -0.56
6419 || orf19.1596 || FGR28 || || Protein lacking an ortholog in S. cerevisiae; transposon mutation affects filamentous growth; possibly an essential gene, disruptants not obtained by UAU1 method || 1 0.08 -0.10 0.21 0.61 -0.34 -0.33 -0.42 -0.69 0.04 -0.44 -1.90 -1.24 -0.68 -0.11 -1.07 -0.77
6420 || orf19.4509 || || || Protein of unknown function || 1 -0.40 -0.43 0.49 -0.22 -0.54 -0.14 -0.33 -0.98 0.07 -0.71 -2.60 -1.93 -1.09 -0.24 -1.64 -1.01
6421 || orf19.4508 || || || Ortholog of Candida albicans WO-1 : CAWG_04200 || 1 -0.27 -0.53 0.62 0.39 -0.46 -0.14 -0.14 -0.84 -0.07 -0.10 -2.88 -2.50 -0.44 -0.48 -1.89 -1.54
6422 || orf19.4508 || || || Ortholog of Candida albicans WO-1 : CAWG_04200 || 1 -0.02 -0.22 0.81 0.70 -0.52 -0.37 -0.07 -0.94 0.06 -0.58 -2.04 -1.55 -0.27 -0.38 -1.65 -1.88
6423 || orf19.3363 || VTC4 || || Putative polyphosphate synthetase; decreased expression in hyphae compared to yeast-form cells; fungal-specific (no human or murine homolog); virulence-group-correlated expression || 1 0.03 -0.09 0.18 0.18 -0.42 -0.34 -0.71 -0.49 -0.24 -0.37 -1.83 -0.94 -0.25 0.40 -1.13 -1.26
6424 || orf19.2809 || CTN3 || || Peroxisomal carnitine acetyl transferase; no obvious metabolic, hyphal, virulence defects in Ura+ strain; induced by macrophage engulfment, hyphal growth, starvation, nonfermentable carbon sources; rat catheter, Spider biofilm induced || 1 0.16 0.13 0.24 0.69 -0.99 -0.10 -0.96 -1.27 0.29 0.07 -2.07 -1.08 -0.71 -0.41 -0.72 -1.41
6425 || orf19.1586 || FGR22 || || Putative phosphatidylinositol-specific phospholipase C (PI-PLC); predicted type 2 membrane protein; no S. cerevisiae ortholog; role in, and regulated by, filamentation, Hap43p; almost identical to orf19.5797 || 1 0.12 -0.06 0.33 0.45 -0.35 -0.49 -0.31 -0.24 -0.06 -0.08 -3.59 -3.35 -0.21 0.76 -2.52 -3.36
6426 || orf19.5797 || PLC2 || || Phosphatidylinositol (PtdIns)-specific phospholipase C (PI-PLC); predicted type 2 membrane protein; role in, and regulated by, filamentation, Nrg1 and Tup1; no mouse systemic virulence role; orf19.5797 and orf19.1586 are almost identical || 1 0.03 -0.10 0.31 0.41 -0.57 -0.48 -0.32 -0.22 -0.09 -0.30 -2.30 -3.24 -0.11 0.47 -2.03 -3.35
6427 || orf19.4568 || ZCF25 || || Putative Zn(II)2Cys6 transcription factor || 1 0.11 0.13 0.23 0.23 -0.68 -0.42 0.06 -0.34 0.76 0.34 -2.02 -1.68 -0.10 -1.39 -1.94
6428 || orf19.6420 || PGA13 || || GPI-anchored cell wall protein involved in cell wall synthesis; required for normal cell surface properties; induced in oralpharyngeal candidasis; Spider biofilm induced; Bcr1-repressed in RPMI a/a biofilms || 1 0.40 0.26 0.41 0.72 -1.94 -1.51 0.67 -0.75 0.64 0.85 -5.33 -4.83 0.19 -2.46 -3.93 -4.77
6429 || orf19.6420 || PGA13 || || GPI-anchored cell wall protein involved in cell wall synthesis; required for normal cell surface properties; induced in oralpharyngeal candidasis; Spider biofilm induced; Bcr1-repressed in RPMI a/a biofilms || 1 0.32 0.29 0.50 1.11 -1.97 -1.63 0.39 -0.96 0.42 0.70 -5.24 -5.49 -0.13 -2.45 -3.91 -4.52
6430 || orf19.6420 || PGA13 || || GPI-anchored cell wall protein involved in cell wall synthesis; required for normal cell surface properties; induced in oralpharyngeal candidasis; Spider biofilm induced; Bcr1-repressed in RPMI a/a biofilms || 1 0.24 0.25 0.27 0.72 -2.11 -1.94 0.40 -0.95 0.09 0.41 -5.65 -5.71 -0.14 -3.08 -4.11 -4.83
6431 || orf19.6420 || PGA13 || || GPI-anchored cell wall protein involved in cell wall synthesis; required for normal cell surface properties; induced in oralpharyngeal candidasis; Spider biofilm induced; Bcr1-repressed in RPMI a/a biofilms || 1 0.22 0.20 0.52 0.95 -2.67 -1.77 0.26 -0.95 0.60 0.55 -5.39 -6.24 -0.37 -2.52 -4.29 -4.14
6432 || orf19.1082.1 || || || Ortholog(s) have cytochrome-c oxidase activity, role in mitochondrial respiratory chain complex IV assembly and cytosol, mitochondrial intermembrane space, mitochondrial respiratory chain complex IV, nucleus localization || 1 0.06 -0.02 0.23 0.04 -0.96 -0.50 -0.18 -0.32 0.34 -0.37 -1.38 -1.19 -0.47 -0.71 -1.22 -1.18
6433 || orf19.4240 || || || Ortholog(s) have role in GPI anchor biosynthetic process, cellular manganese ion homeostasis and endoplasmic reticulum, fungal-type vacuole membrane localization || 1 -0.12 -0.21 0.17 0.12 -0.53 -0.25 -0.26 -0.22 -0.17 0.08 -0.64 -0.51 -0.30 -0.26 -0.27 -0.71
6434 || orf19.4749 || || || Protein of unknown function; hyphal-induced expression, regulated by Cyr1, Ras1, Efg1; Hap43-induced gene; Spider biofilm induced || 1 0.02 -0.01 0.11 0.56 -1.20 -0.52 -0.93 -0.50 -0.38 0.00 -1.38 -0.78 -0.37 0.01 -1.57 -1.79
6435 || orf19.4749 || || || Protein of unknown function; hyphal-induced expression, regulated by Cyr1, Ras1, Efg1; Hap43-induced gene; Spider biofilm induced || 1 -0.24 -0.49 -0.26 0.43 -1.24 -0.29 -0.89 -0.61 -0.52 0.01 -1.57 -0.73 -0.66 -0.09 -1.63 -1.33
6436 || orf19.2160 || NAG4 || || Putative transporter; fungal-specific; similar to Nag3p and to S. cerevisiae Ypr156Cp and Ygr138Cp; required for wild-type mouse virulence and wild-type cycloheximide resistance; gene cluster encodes enzymes of GlcNAc catabolism || 1 -0.24 -0.36 0.45 0.53 -0.70 -0.13 -0.28 -0.26 -0.34 0.06 -0.99 -1.09 -0.65 -0.31 -1.55 -1.21
6437 || orf19.7380 || || || Has domain(s) with predicted nucleic acid binding, nucleotide binding activity || 1 -0.39 -0.58 0.10 0.08 -0.61 -0.10 -0.30 -0.25 0.35 -0.11 -1.04 -0.76 -0.04 -0.58 -0.73 -1.08
6438 || orf19.6028 || HGC1 || || Hypha-specific G1 cyclin-related protein involved in regulation of morphogenesis, biofilm formation; Cdc28-Hgc1 maintains Cdc11 S394 phosphorylation during hyphal growth; required for virulence in mice; regulated by Nrg1, Tup1, farnesol || 1 -0.44 -0.49 -0.62 0.12 -0.72 -1.05 -1.12 -1.69 0.09 1.18 -2.27 -2.20 -0.05 -1.26 -1.33 -2.22
6439 || orf19.3829 || PHR1 || || Cell surface glycosidase; may act on cell-wall beta-1,3-glucan prior to beta-1,6-glucan linkage; role in systemic, not vaginal virulence (neutral, not low pH); high pH or filamentation induced; Bcr1-repressed in RPMI a/a biofilm || 1 0.13 0.29 0.07 0.08 -0.49 -0.73 -0.42 -0.62 0.22 1.00 -1.46 -1.88 0.22 -0.69 -0.72 -1.67
6440 || orf19.3923 || PGA37 || || Putative GPI-anchored protein; Hap43-repressed; Spider biofilm induced || 1 -0.10 0.09 -0.01 0.56 -0.51 -2.00 0.23 -0.17 0.69 0.11 -0.82 -1.63 -0.65 0.61 -0.98 -2.18
6441 || orf19.3897 || || || Protein of unknown function; decreased transcription is observed upon fluphenazine treatment or in an azole-resistant strain that overexpresses CDR1 and CDR2; transcription is repressed in response to alpha pheromone in SpiderM medium || 1 0.28 0.26 0.40 -0.35 -0.60 -2.97 -0.49 0.18 0.06 0.41 -1.24 -3.06 0.80 1.57 -0.88 -2.40
6442 || orf19.3897 || || || Protein of unknown function; decreased transcription is observed upon fluphenazine treatment or in an azole-resistant strain that overexpresses CDR1 and CDR2; transcription is repressed in response to alpha pheromone in SpiderM medium || 1 0.32 0.31 0.02 -0.83 -1.44 -2.67 -0.59 0.35 -0.09 0.49 -1.79 -3.98 1.09 1.58 -1.44 -3.25
6443 || orf19.4342 || SUT1 || || Zn2Cys6 transcription factor involved in sterol uptake; flow model biofilm induced; Spider biofilm repressed || 1 -1.09 -0.72 -0.25 0.55 -1.76 -1.50 0.67 0.25 -0.43 0.89 -2.16 -2.97 1.88 0.32 -1.38 -1.36
6444 || orf19.4342 || SUT1 || || Zn2Cys6 transcription factor involved in sterol uptake; flow model biofilm induced; Spider biofilm repressed || 1 -2.34 -2.18 -1.14 0.03 -3.69 -2.09 0.08 -0.16 -0.91 0.46 -3.60 -3.53 1.50 0.26 -2.83 -1.55
6445 || orf19.2903 || AGO1 || || Putative Argonaute protein involved in RNA silencing; hyphal-induced expression; regulated by Cyr1, Ras1, Efg1, Nrg1, Tup1; rat catheter biofilm repressed || 1 -0.18 -0.25 -0.31 -0.37 -1.00 -0.80 -0.16 -0.40 0.17 -0.10 -1.19 -0.63 0.26 0.49 -0.79 -0.24
6446 || orf19.4211 || FET3 || || Multicopper oxidase; for growth in low iron, prostaglandin E2 synthesis; ketoconazole/caspofungin/amphotericin B repressed; Sef1/Sfu1/Hap43 regulated; reports differ if functional homolog of ScFet3; rat catheter and Spider biofilm induced || 1 -0.32 -0.21 -0.16 0.12 -3.69 -4.16 0.13 0.01 0.05 -0.69 -3.15 -3.46 1.90 1.37 -3.33 -1.23
6447 || orf19.4211 || FET3 || || Multicopper oxidase; for growth in low iron, prostaglandin E2 synthesis; ketoconazole/caspofungin/amphotericin B repressed; Sef1/Sfu1/Hap43 regulated; reports differ if functional homolog of ScFet3; rat catheter and Spider biofilm induced || 1 -0.60 -0.68 -0.90 -0.75 -5.06 -5.54 0.21 -0.07 -0.37 -0.81 -3.49 -3.88 2.04 1.49 -4.87 -1.33
6448 || orf19.4211 || FET3 || || Multicopper oxidase; for growth in low iron, prostaglandin E2 synthesis; ketoconazole/caspofungin/amphotericin B repressed; Sef1/Sfu1/Hap43 regulated; reports differ if functional homolog of ScFet3; rat catheter and Spider biofilm induced || 1 -1.03 -1.01 -0.83 -0.64 -6.59 -6.33 -0.20 -0.44 -0.63 -0.88 -4.15 -3.58 1.81 1.47 -5.72 -0.95
6449 || orf19.4211 || FET3 || || Multicopper oxidase; for growth in low iron, prostaglandin E2 synthesis; ketoconazole/caspofungin/amphotericin B repressed; Sef1/Sfu1/Hap43 regulated; reports differ if functional homolog of ScFet3; rat catheter and Spider biofilm induced || 1 -1.09 -1.08 -0.62 -0.59 -2.80 -2.27 -0.22 -0.33 -0.33 -0.97 -2.02 -2.02 1.55 1.33 -2.30 -0.36
6450 || orf19.4215 || FET34 || || Multicopper ferroxidase; induced by low iron, ciclopirox olamine, ketoconazole, hypoxia; alkaline induced by Rim101; repressed in fluconazole-resistant isolate; Sfu1, Hog1 repressed; complements S. cerevisiae fet3; Spider biofilm induced || 1 -0.51 -0.62 -0.87 -0.69 -3.86 -4.31 0.06 -0.05 -0.36 -1.11 -1.11 -2.35 1.95 1.13 -3.13 0.67
6451 || orf19.3394 || || || Predicted membrane protein; induced by alpha pheromone in SpiderM medium || 1 -0.52 -0.10 -0.17 -0.09 -1.31 -1.74 -0.41 -0.22 -0.37 -0.20 -0.34 -0.51 0.51 0.24 -1.09 -0.25
6452 || orf19.4286 || || || Protein of unknown function; flow model biofilm induced; Spider biofilm induced || 1 -0.26 -0.44 -0.43 -0.38 -0.97 -0.82 0.15 0.01 -0.28 -0.72 -0.21 -1.09 0.61 0.60 -1.16 -0.07
6453 || orf19.4792 || || || Protein with a regulator of G-protein signaling domain; Plc1-regulated; Spider biofilm induced; rat catheter biofilm repressed || 1 -0.20 -0.15 -0.25 -0.16 -1.41 -0.53 1.08 -0.89 -0.01 -0.37 -1.00 -1.39 0.51 0.74 -1.05 -0.72
6454 || orf19.4792 || || || Protein with a regulator of G-protein signaling domain; Plc1-regulated; Spider biofilm induced; rat catheter biofilm repressed || 1 -0.65 -0.54 -0.65 -0.11 -1.76 -0.76 0.70 -1.43 -0.24 -0.58 -1.16 -1.29 0.49 0.24 -1.77 -0.89
6455 || orf19.3663 || PHO91 || || Putative low-affinity phosphate transporter; fungal-specific (no human or murine homolog) || 1 -0.28 -0.36 -0.19 -0.43 -0.61 -0.32 0.08 -0.54 -0.01 -0.14 -0.64 -0.72 0.41 0.55 -1.16 -0.61
6456 || orf19.2841 || PGM2 || || Ortholog of S. cerevisiae Pgm2; induced in planktonic culture; Tye7p-regulated; flow model biofilm induced; rat catheter biofilm repressed || 1 -0.32 -0.35 -0.13 -0.64 -1.12 -0.61 0.15 -0.71 0.09 -1.17 -1.25 -0.63 0.60 0.20 -0.77 -0.60
6457 || orf19.6500 || ECM42 || || Ornithine acetyltransferase; Gcn2, Gcn4-regulated; clade-specific gene expression; possibly essential gene, disruptants not obtained by UAU1 method; Spider biofilm induced || 1 -1.03 -0.66 0.32 0.24 -1.58 -0.60 -0.52 -0.76 0.10 -0.68 -1.26 -0.51 0.40 0.56 -0.87 -0.59
6458 || orf19.6500 || ECM42 || || Ornithine acetyltransferase; Gcn2, Gcn4-regulated; clade-specific gene expression; possibly essential gene, disruptants not obtained by UAU1 method; Spider biofilm induced || 1 -0.88 -0.92 -0.33 -0.22 -1.88 -0.93 -0.37 -1.08 -0.24 -0.92 -1.61 -0.80 0.56 0.55 -0.97 -0.78
6459 || orf19.1911 || PGA52 || || GPI-anchored cell surface protein of unknown function; Hap43p-repressed gene; fluconazole-induced; possibly an essential gene, disruptants not obtained by UAU1 method || 1 -0.42 -0.51 0.00 -0.09 -0.73 -0.36 -0.21 -0.32 0.11 -0.71 -0.98 -0.62 0.24 0.11 -0.46 -0.11
6460 || orf19.6574 || ALK6 || || Putative cytochrome P-450 of N-alkane-induced detoxification; macrophage-induced gene || 1 -1.42 -1.17 0.13 -0.34 -2.39 -1.04 0.33 -1.00 0.58 -1.42 -2.95 -2.19 0.65 0.38 -2.34 -0.49
6461 || orf19.6574 || ALK6 || || Putative cytochrome P-450 of N-alkane-induced detoxification; macrophage-induced gene || 1 -0.76 -1.09 0.61 0.36 -1.20 -0.75 0.31 -0.65 0.87 -0.75 -1.99 -0.98 0.51 0.24 -1.81 -0.31
6462 || orf19.6574 || ALK6 || || Putative cytochrome P-450 of N-alkane-induced detoxification; macrophage-induced gene || 1 -0.51 -0.88 0.21 -0.04 -1.11 -0.62 0.54 -0.13 1.23 -0.99 -1.62 -1.05 0.91 1.18 -2.06 -0.43
6463 || orf19.6078 || POL93 || || Predicted ORF in retrotransposon Tca8 with similarity to the Pol region of retrotransposons encoding reverse transcriptase, protease and integrase; downregulated in response to ciclopirox olamine; F-12/CO2 early biofilm induced || 1 0.06 -0.76 1.63 1.26 -2.65 -0.98 -1.01 -1.51 1.09 -1.04 -2.58 -2.66 2.28 0.94 -2.83 -2.55
6464 || orf19.5285 || PST3 || || Putative flavodoxin; YNB biofilm induced; stationary phase enriched protein; rat catheter and Spider biofilm repressed || 1 0.09 0.12 0.70 0.54 -1.77 -0.75 0.09 -0.11 0.39 -0.45 -0.82 -0.89 0.83 0.28 -1.42 -0.67
6465 || orf19.5285 || PST3 || || Putative flavodoxin; YNB biofilm induced; stationary phase enriched protein; rat catheter and Spider biofilm repressed || 1 -0.32 -0.26 0.62 0.76 -2.32 -1.10 -0.31 -0.44 0.18 -0.72 -1.16 -1.14 0.55 -0.08 -1.36 -0.89
6466 || orf19.5619 || || || Protein of unknown function; induced by alpha pheromone in SpiderM medium; Spider biofilm induced || 1 -0.05 -0.18 0.30 0.80 -1.02 -0.21 -0.23 -0.25 0.21 -0.08 -0.53 -0.47 -0.29 0.05 -0.63 -0.10
6467 || orf19.6459 || DPP3 || || Protein similar to S. cerevisiae pyrophosphate phosphatase Dpp1; required for farnesol biosynthesis; repressed by 17-beta-estradiol, ethynyl estradiol; Spider biofilm induced || 1 -0.39 -0.37 0.58 0.68 -1.50 -0.89 -0.68 -0.47 0.20 0.07 -1.15 -0.39 0.03 -0.29 -0.64 -0.34
6468 || orf19.6459 || DPP3 || || Protein similar to S. cerevisiae pyrophosphate phosphatase Dpp1; required for farnesol biosynthesis; repressed by 17-beta-estradiol, ethynyl estradiol; Spider biofilm induced || 1 -0.25 -0.23 0.41 0.64 -1.22 -0.67 -0.28 -0.66 0.01 0.10 -0.85 -0.18 -0.14 0.36 -0.57 0.03
6469 || orf19.4923 || || || Predicted membrane transporter; sugar porter (SP) family member, major facilitator superfamily; caspofungin induced; Spider biofilm induced || 1 -0.22 -0.21 0.72 0.54 -1.29 -1.09 -0.46 -1.10 0.29 -0.30 -1.51 -0.68 -0.56 0.38 -0.88 -0.17
6470 || orf19.4923 || || || Predicted membrane transporter; sugar porter (SP) family member, major facilitator superfamily; caspofungin induced; Spider biofilm induced || 1 -0.19 -0.15 0.50 0.43 -1.19 -0.59 -0.27 -1.22 0.11 -0.62 -1.46 -0.95 0.27 0.51 -0.70 -0.54
6471 || orf19.3122 || ARR3 || || Ortholog of S. cerevisiae Arr3; arsenite transporter of the plasma membrane required for resistance to arsenic compounds; benomyl-induced; Gcn4-regulated; Hap43-repressed; mutant is viable; Spider biofilm induced || 1 -0.55 -0.52 0.78 0.86 -1.31 -0.48 -0.15 -0.86 0.37 -0.57 -2.09 -0.74 -0.15 -0.12 -1.25 -1.02
6472 || orf19.1325 || ECM38 || || Putative gamma-glutamyltransferase; alkaline upregulated; Spider biofilm induced; possibly an essential gene, disruptants not obtained by UAU1 method || 1 -0.19 0.06 0.54 1.20 -1.31 -1.12 -0.01 -0.25 0.03 -0.10 -1.89 -1.42 -0.18 0.13 -0.97 -0.54
6473 || orf19.1325 || ECM38 || || Putative gamma-glutamyltransferase; alkaline upregulated; Spider biofilm induced; possibly an essential gene, disruptants not obtained by UAU1 method || 1 -0.02 0.00 0.59 0.94 -1.10 -0.69 0.10 -0.16 0.68 -0.01 -1.87 -1.28 -0.03 0.69 -0.58 -0.43
6474 || orf19.4916 || || || Protein of unknown function; induced by alpha pheromone in SpiderM medium || 1 0.23 0.16 0.61 0.75 -0.52 -0.50 -0.14 -0.11 0.36 -0.41 -1.00 -0.54 0.07 0.29 -0.87 -0.42
6475 || orf19.3142 || || || Ortholog of C. dubliniensis CD36 : Cd36_46140, C. parapsilosis CDC317 : CPAR2_501210, Candida tenuis NRRL Y-1498 : CANTEDRAFT_97195 and Debaryomyces hansenii CBS767 : DEHA2E08800g || 1 -0.13 -0.22 0.15 0.22 -1.05 -1.04 0.32 -0.35 0.55 -1.03 -1.46 -0.41 -0.04 0.02 -0.91 -0.34
6476 || orf19.1369 || || || Protein with predicted peptidase domains; Hap43-repressed gene || 1 -0.22 -0.29 0.24 0.66 -1.29 -1.50 -0.30 -0.30 0.14 -0.80 -1.24 -0.72 -0.35 -0.17 -0.76 -0.34
6477 || orf19.1158 || || || Ortholog of S. cerevisiae Yft2 required for normal ER membrane biosynthesis; Hap43-repressed gene || 1 -0.03 -0.32 0.25 -0.04 -0.80 -0.70 -0.06 0.14 0.12 -0.78 -0.74 -0.58 -0.19 -0.05 -0.53 -0.31
6478 || orf19.5311 || || || Ortholog of C. dubliniensis CD36 : Cd36_43850, C. parapsilosis CDC317 : CPAR2_402060, Pichia stipitis Pignal : PICST_68242, Candida tropicalis MYA-3404 : CTRG_00303 and Candida albicans WO-1 : CAWG_03390 || 1 0.12 0.31 0.68 0.74 -0.13 -0.50 -0.05 0.01 0.16 -0.27 -1.07 -0.70 0.33 0.28 -0.49 -0.67
6479 || orf19.4504 || || || Has domain(s) with predicted oxidoreductase activity, transferase activity, transferring acyl groups other than amino-acyl groups, zinc ion binding activity and role in oxidation-reduction process || 1 0.21 0.14 1.56 1.41 -0.60 -0.42 0.12 0.29 -0.26 -0.37 -3.19 -2.51 0.79 0.18 -1.45 -1.96
6480 || orf19.1557 || || || Ortholog(s) have S-adenosylmethionine-dependent methyltransferase activity, role in protein methylation and cytosol, nucleus localization || 1 0.46 0.45 1.08 0.80 -0.33 -0.87 0.20 0.14 0.32 0.08 -1.51 -2.51 0.23 0.28 -1.08 -1.33
6481 || orf19.4826 || IDH1 || || Putative mitochondrial NAD-isocitrate dehydrogenase subunit 1; soluble protein in hyphae; protein level decrease in stationary phase cultures || 1 0.49 0.32 0.40 0.31 0.11 -0.18 -0.06 -0.03 0.01 0.12 -0.68 -1.39 0.15 0.32 -0.78 -0.93
6482 || orf19.4826 || IDH1 || || Putative mitochondrial NAD-isocitrate dehydrogenase subunit 1; soluble protein in hyphae; protein level decrease in stationary phase cultures || 1 0.33 0.46 0.39 0.30 -0.07 -0.36 -0.16 -0.11 -0.05 0.09 -1.10 -1.45 0.27 0.37 -1.16 -0.76
6483 || orf19.1611 || || || Protein of unknown function; Spider biofilm induced || 1 0.83 0.90 0.52 0.41 -1.07 -1.15 -0.34 -0.37 -0.31 -0.11 -2.07 -3.03 -0.05 0.19 -1.34
6484 || orf19.2062 || SOD4 || || Cu and Zn-containing superoxide dismutase; role in response to host innate immune ROS; regulated on white-opaque switch; ciclopirox olamine induced; caspofungin repressed; SOD1,4,5,6 gene family; yeast-associated; Spider biofilm induced || 1 0.35 0.33 0.65 0.79 -1.03 -1.67 -0.31 -0.62 -1.00 -1.41 -2.86 -3.80 0.61 1.65 -1.32 -1.87
6485 || orf19.2062 || SOD4 || || Cu and Zn-containing superoxide dismutase; role in response to host innate immune ROS; regulated on white-opaque switch; ciclopirox olamine induced; caspofungin repressed; SOD1,4,5,6 gene family; yeast-associated; Spider biofilm induced || 1 0.27 0.19 0.54 0.65 -1.53 -1.65 -0.30 -0.67 -1.15 -1.47 -3.99 -4.04 0.86 1.61 -1.87 -1.79
6486 || orf19.2062 || SOD4 || || Cu and Zn-containing superoxide dismutase; role in response to host innate immune ROS; regulated on white-opaque switch; ciclopirox olamine induced; caspofungin repressed; SOD1,4,5,6 gene family; yeast-associated; Spider biofilm induced || 1 0.61 0.53 0.73 1.07 -1.58 -1.70 -0.12 -0.24 -1.27 -1.56 -4.11 -4.36 1.07 1.21 -1.86 -2.17
6487 || orf19.2062 || SOD4 || || Cu and Zn-containing superoxide dismutase; role in response to host innate immune ROS; regulated on white-opaque switch; ciclopirox olamine induced; caspofungin repressed; SOD1,4,5,6 gene family; yeast-associated; Spider biofilm induced || 1 0.68 0.67 0.56 0.75 -1.07 -1.71 0.11 -0.21 -1.07 -1.48 -3.16 -3.86 1.28 1.37 -1.54 -1.94
6488 || orf19.2156 || NAG1 || || Glucosamine-6-phosphate deaminase; required for normal hyphal growth and mouse virulence; converts glucosamine 6-P to fructose 6-P; reversible reaction in vitro; gene and protein is GlcNAc-induced; Spider biofilm induced || 1 1.05 1.10 0.79 0.64 -1.33 -1.54 0.07 0.38 -0.40 -0.48 -2.43 -3.59 1.91 1.64 -1.83 -2.86
6489 || orf19.2156 || NAG1 || || Glucosamine-6-phosphate deaminase; required for normal hyphal growth and mouse virulence; converts glucosamine 6-P to fructose 6-P; reversible reaction in vitro; gene and protein is GlcNAc-induced; Spider biofilm induced || 1 0.95 0.91 0.90 0.76 -1.32 -1.30 0.15 0.31 -0.46 -0.36 -2.43 -3.34 2.09 1.76 -2.07 -3.03
6490 || orf19.5290 || || || Protein of unknown function; repressed by Sfu1; Hap43-induced gene || 1 0.88 1.09 1.04 1.41 -0.96 -1.29 0.18 -0.55 0.09 -0.71 -2.28 -2.65 1.43 1.50 0.16 -2.59
6491 || orf19.1430 || || || Ortholog of C. parapsilosis CDC317 : CPAR2_402120, C. dubliniensis CD36 : Cd36_43870, Lodderomyces elongisporus NRLL YB-4239 : LELG_04437 and Candida orthopsilosis Co 90-125 : CORT_0E02170 || 1 0.85 0.73 1.22 1.23 -1.01 -1.42 0.18 -0.56 -0.30 -0.60 -2.06 -3.11 1.20 1.51 0.33 -1.92
6492 || orf19.1430 || || || Ortholog of C. parapsilosis CDC317 : CPAR2_402120, C. dubliniensis CD36 : Cd36_43870, Lodderomyces elongisporus NRLL YB-4239 : LELG_04437 and Candida orthopsilosis Co 90-125 : CORT_0E02170 || 1 0.62 0.75 1.38 1.62 -1.16 -1.13 -0.04 -0.62 -0.14 -0.88 -2.14 -2.54 0.98 1.50 0.20 -1.65
6493 || orf19.5290 || || || Protein of unknown function; repressed by Sfu1; Hap43-induced gene || 1 0.73 0.71 1.40 1.52 -1.10 -1.05 -0.18 -0.71 -0.01 -0.48 -2.35 -2.29 1.13 1.48 0.15 -1.84
6494 || orf19.263.1 || || || Protein of unknown function; gene has intron; Spider biofilm induced || 1 0.45 0.46 1.08 1.40 -1.06 -0.42 -0.24 -0.78 -0.39 -0.54 -1.47 -0.96 0.62 0.68 -0.43 -0.93
6495 || orf19.263.1 || || || Protein of unknown function; gene has intron; Spider biofilm induced || 1 0.40 0.31 0.51 0.87 -1.35 -0.72 -0.23 -0.89 -0.82 -0.76 -1.60 -1.21 0.57 0.53 -0.39 -1.29
6496 || orf19.4599 || PHO89 || || Putative phosphate permease; transcript regulated upon white-opaque switch; alkaline induced by Rim101; possibly adherence-induced; F-12/CO2 model, rat catheter and Spider biofilm induced || 1 0.30 0.41 1.31 0.55 -0.21 -1.65 -0.88 -1.10 -0.78 -0.53 -1.05 -2.25 1.11 1.15 -0.62 -1.07
6497 || orf19.4649 || ZCF27 || || Putative Zn(II)2Cys6 transcription factor || 1 -0.18 -0.20 0.13 -0.18 -0.43 -0.39 -0.14 -0.14 0.30 -0.14 -0.68 -0.55 0.78 0.37 -0.55 -0.72
6498 || orf19.4281 || || || Transcription factor; forms a heterodimer with Fhl11 that is tethered to promoters by Tbf1; positively regulates rRNA and ribosomal protein gene transcription; merged with orf19.4282; Spider biofilm induced || 1 -0.23 -0.24 0.06 0.07 -0.69 -0.50 -0.38 -0.09 0.56 0.40 -1.13 -0.87 0.84 0.64 -0.55 -1.00
6499 || orf19.5105 || MED15 || || RNA polymerase II mediator complex subunit; possibly an essential gene, disruptants not obtained by UAU1 method || 1 -0.10 -0.13 0.22 0.29 -0.29 -0.29 -0.07 0.05 0.31 0.15 -1.18 -0.60 0.21 0.31 -0.74 -0.70
6500 || orf19.1424 || || || Predicted membrane transporter, member of the oxalate:formate antiporter (OFA) family, major facilitator superfamily (MFS) || 1 -0.34 -0.33 0.16 0.48 -0.42 -0.75 0.24 0.42 0.63 0.05 -0.98 -0.33 0.13 0.42 -0.43 -0.59
6501 || orf19.4995 || || || Ortholog of C. dubliniensis CD36 : Cd36_12580 || 1 -0.19 -0.01 0.14 0.34 -0.50 -0.74 0.63 0.01 0.80 0.05 -1.00 -0.45 0.39 0.69 -0.41 -0.35
6502 || orf19.176 || OPT4 || || Oligopeptide transporter; detected at germ tube plasma membrane; transcript inducede during phagocytosis by macrophages; fungal-specific; Hap43-repressed; merged with orf19.2292 in Assembly 20; rat catheter and Spider biofilm induced || 1 -0.63 -0.66 0.56 0.35 -1.08 -1.05 0.92 0.57 1.15 0.12 -1.44 -1.46 0.25 0.89 -0.54 -1.14
6503 || orf19.3749 || IFC3 || || Oligopeptide transporter; transcript induced by macrophage phagocytosis, BSA or peptides; fluconazole-induced; induced by Rim101 at pH 8; virulence-group-correlated expression; Hap43-repressed; Spider biofilm induced || 1 -0.39 -0.53 0.25 -0.06 -0.56 -1.04 0.77 0.48 1.01 0.11 -1.54 -1.46 0.41 0.91 -0.46 -1.12
6504 || orf19.176 || OPT4 || || Oligopeptide transporter; detected at germ tube plasma membrane; transcript inducede during phagocytosis by macrophages; fungal-specific; Hap43-repressed; merged with orf19.2292 in Assembly 20; rat catheter and Spider biofilm induced || 1 -0.47 -0.11 0.41 -0.05 -0.48 -1.28 0.94 0.46 1.19 0.03 -2.12 -1.96 0.77 0.94 -0.87 -1.80
6505 || orf19.5508 || || || Ortholog of Candida albicans WO-1 : CAWG_05700 || 1 0.05 0.12 0.15 -0.10 -0.50 -1.31 0.73 0.50 1.14 0.12 -1.09 -1.47 0.70 0.54 -0.51 -0.76
6506 || orf19.6690 || || || Protein of unknown function; Hap43-repressed gene || 1 0.09 0.21 0.44 0.19 -0.27 -0.88 0.25 0.48 1.19 -0.12 -0.80 -1.50 0.18 0.44 -0.54 -0.76
6507 || orf19.3749 || IFC3 || || Oligopeptide transporter; transcript induced by macrophage phagocytosis, BSA or peptides; fluconazole-induced; induced by Rim101 at pH 8; virulence-group-correlated expression; Hap43-repressed; Spider biofilm induced || 1 0.37 0.45 0.28 0.02 -0.12 -0.65 1.16 0.52 1.46 0.06 -2.13 -1.73 0.89 0.94 -1.23 -1.37
6508 || orf19.1714 || PGA44 || || Putative GPI-anchored protein || 1 0.23 0.25 -0.12 0.61 -1.14 -1.34 0.46 1.19 0.34 0.47 -1.35 -5.44 0.53 0.52 -1.02 -1.63
6509 || orf19.3134 || || || Protein of unknown function; flow model biofilm induced || 1 0.02 -0.23 -0.37 0.03 -1.45 0.43 0.11 0.77 0.16 -1.96 -5.26 -0.02 0.63 -1.17 -2.51
6510 || orf19.4571 || || || CoA-transferase family protein; rat catheter biofilm repressed || 1 0.10 0.19 0.32 0.47 -0.58 -0.63 -0.35 -0.31 0.33 0.09 -0.97 -2.67 -0.70 0.25 -0.94 -1.84
6511 || orf19.2575 || || || Putative S-adenosylmethionine-dependent methyltransferase; Hap43p-induced gene || 1 0.23 0.48 -0.06 0.27 -0.34 0.12 -0.50 -0.26 -0.35 0.81 -0.75 -1.12 -0.79 -0.19 -1.13 -0.34
6512 || orf19.2045 || || || Ortholog(s) have diacylglycerol kinase activity, role in phosphatidic acid biosynthetic process and integral to endoplasmic reticulum membrane localization || 1 0.33 0.25 0.04 0.23 -0.97 -0.49 -0.62 -0.30 -1.26 0.62 -0.68 -1.08 -0.70 -0.08 -1.73 -0.79
6513 || orf19.2045 || || || Ortholog(s) have diacylglycerol kinase activity, role in phosphatidic acid biosynthetic process and integral to endoplasmic reticulum membrane localization || 1 0.36 0.28 0.38 0.28 -0.95 -0.47 -1.14 -0.49 -1.24 0.82 -0.75 -0.83 -0.89 -0.20 -2.12 -0.63
6514 || orf19.5294 || PDB1 || || Putative pyruvate dehydrogenase; fluconazole-induced; protein level decreases in stationary phase cultures; Spider biofilm repressed || 1 0.25 0.20 -0.16 0.04 -0.90 -0.26 -0.47 -0.40 -0.49 -0.35 -0.60 -0.62 -0.51 -0.29 -1.08 -0.38
6515 || orf19.5294 || PDB1 || || Putative pyruvate dehydrogenase; fluconazole-induced; protein level decreases in stationary phase cultures; Spider biofilm repressed || 1 0.41 0.26 0.03 0.01 -0.64 -0.03 -0.31 -0.11 -0.20 -0.07 -0.41 -0.54 -0.39 0.06 -0.88 -0.21
6516 || orf19.732 || || || Possible dehydrogenase; flow model biofilm induced; rat catheter biofilm induced; Spider biofilm induced || 1 0.63 0.61 -0.20 0.27 -0.90 -0.39 -0.13 -0.42 0.17 -0.33 -0.84 -0.57 -0.62 -0.02 -1.08 -0.63
6517 || orf19.3097 || PDA1 || || Putative pyruvate dehydrogenase alpha chain; fluconazole-induced; protein present in exponential and stationary growth phase yeast cultures; Hap43-induced; Spider biofilm repressed || 1 0.38 0.24 -0.08 -0.24 -0.60 -0.37 -0.04 0.04 -0.17 0.02 -0.63 -0.75 -0.19 0.17 -0.87 -0.25
6518 || orf19.5061 || ADE5,7 || || Phosphoribosylamine-glycine ligase and phosphoribosylformylglycinamidine cyclo-ligase; interacts with Vps34p; required for hyphal growth and virulence; flucytosine induced; not induced in GCN response, in contrast to S. cerevisiae ortholog || 1 0.47 0.58 0.30 0.44 -0.37 0.08 -0.26 0.10 0.16 0.22 -0.70 -0.72 -0.39 0.21 -0.90 -0.31
6519 || orf19.5021 || PDX1 || || Pyruvate dehydrogenase complex protein X; essential component of the mitochondrial pyruvate dehydrogenase complex; role in the respiratory pathway; protein present in exponential and stationary growth phase yeast; Spider biofilm repressed || 1 0.71 0.65 0.58 0.19 -0.31 -0.10 -0.43 0.11 -0.10 0.10 -0.90 -1.03 -0.16 0.18 -1.30 -0.47
6520 || orf19.6073 || HMX1 || || Heme oxygenase; utilization of hemin iron; transcript induced by heat, low iron, or hemin; repressed by Efg1; induced by low iron; upregulated by Rim101 at pH 8; Hap43-induced; Spider and flow model biofilm induced || 1 1.78 1.60 1.01 0.78 -1.22 -0.87 -1.75 -0.84 -1.42 -0.43 -1.71 -2.51 -1.48 0.35 -3.63 -1.77
6521 || orf19.6073 || HMX1 || || Heme oxygenase; utilization of hemin iron; transcript induced by heat, low iron, or hemin; repressed by Efg1; induced by low iron; upregulated by Rim101 at pH 8; Hap43-induced; Spider and flow model biofilm induced || 1 1.97 1.72 1.79 1.51 -1.01 -0.44 -1.06 -0.50 -0.76 0.08 -1.26 -1.61 -1.11 0.54 -2.09 -0.99
6522 || orf19.4015 || CAG1 || || heterotrimeric G protein alpha subunit; positive role in mating pheromone response; opaque-enriched transcript; transcript repressed by MTLa1-MTLalpha2; regulated by hemoglobin-responsive Hbr1 via MTL genes; rat catheter biofilm repressed || 1 0.64 0.50 0.47 0.26 -0.28 -0.24 0.01 -0.07 -0.13 -0.22 -0.69 -0.70 -0.09 0.29 -0.67 -0.25
6523 || orf19.35 || || || Predicted kinase; rat catheter, flow model, Spider biofilm induced || 1 0.92 0.96 0.66 0.35 -0.08 -0.45 -0.42 -0.48 -0.50 -0.57 -0.79 -0.86 -0.62 0.31 -0.81 -0.10
6524 || orf19.3904 || MRV4 || || Protein of unknown function; Spider biofilm induced || 1 0.84 0.69 0.74 0.85 -0.49 -0.29 -0.56 -0.68 -1.37 -0.11 -1.57 -0.68 -0.56 0.62 -1.13 0.20
6525 || orf19.1449 || || || Protein of unknown function; induced in azole-resistant strain that overexpresses MDR1; protein present in exponential and stationary growth phase yeast cultures; Spider biofilm induced || 1 1.10 1.08 0.71 1.14 -0.52 0.18 -1.15 -0.87 -0.79 -0.05 -2.11 -1.00 -0.91 0.34 -1.12 -0.52
6526 || orf19.192 || || || Ortholog of C. dubliniensis CD36 : Cd36_19320, C. parapsilosis CDC317 : CPAR2_209670, Candida tenuis NRRL Y-1498 : CANTEDRAFT_113478 and Debaryomyces hansenii CBS767 : DEHA2C15136g || 1 0.20 0.34 0.36 0.38 -0.16 -0.65 -0.72 -0.84 -0.48 -0.62 -0.50 -0.59 -0.28 0.23 -0.62 -0.49
6527 || orf19.2192 || GDH2 || || Putative NAD-specific glutamate dehydrogenase; fungal-specific; transcript regulated by Nrg1, Mig1, Tup1, and Gcn4; stationary phase enriched protein; flow model biofilm induced; Spider biofilm induced || 1 0.99 0.99 1.74 1.88 -1.19 -2.72 -1.07 -0.92 -1.34 -1.46 -1.41 -1.90 -0.47 0.34 -1.29 -1.06
6528 || orf19.2192 || GDH2 || || Putative NAD-specific glutamate dehydrogenase; fungal-specific; transcript regulated by Nrg1, Mig1, Tup1, and Gcn4; stationary phase enriched protein; flow model biofilm induced; Spider biofilm induced || 1 0.89 0.89 1.51 1.76 -1.56 -2.67 -1.27 -1.32 -1.54 -1.54 -1.49 -1.72 -0.67 0.70 -1.27 -0.43
6529 || orf19.3376 || || || Ortholog of Candida albicans WO-1 : CAWG_03459 || 1 0.27 0.26 1.03 1.50 -0.89 -2.04 -0.72 -1.12 -0.24 -1.10 -1.14 -0.88 -1.36 -0.04 -0.87 -0.50
6530 || orf19.6048 || || || Protein of unknown function; Spider biofilm induced || 1 0.23 0.02 0.52 0.53 -0.54 -0.44 -1.05 -0.18 0.17 -0.17 -0.80 -0.29 -0.75 -0.26 -0.35 -0.83
6531 || orf19.677 || CHO1 || || Putative phosphatidylserine synthase; ortholog of S. cerevisiae CHO1; transposon mutation affects filamentous growth; regulated by Nrg1, Tup1 || 1 0.42 0.18 0.59 0.86 -0.38 -0.12 -1.13 -0.49 -0.27 0.01 -0.86 -0.63 -0.61 -0.59 -0.52 -1.74
6532 || orf19.2990 || XOG1 || || Exo-1,3-beta-glucanase; 5 glycosyl hydrolase family member; affects sensitivity to chitin and glucan synthesis inhibitors; not required for yeast-to-hypha transition or for virulence in mice; Hap43-induced; Spider biofilm induced || 1 0.70 0.66 0.82 1.33 -1.74 -0.18 -0.10 -0.22 0.11 0.15 -1.04 -0.27 -1.00 -0.90 -0.39 -3.04
6533 || orf19.2990 || XOG1 || || Exo-1,3-beta-glucanase; 5 glycosyl hydrolase family member; affects sensitivity to chitin and glucan synthesis inhibitors; not required for yeast-to-hypha transition or for virulence in mice; Hap43-induced; Spider biofilm induced || 1 0.66 0.66 0.82 1.18 -1.61 -0.36 -0.11 -0.23 -0.07 0.00 -1.18 -0.48 -1.10 -1.34 -0.91 -2.94
6534 || orf19.4749 || || || Protein of unknown function; hyphal-induced expression, regulated by Cyr1, Ras1, Efg1; Hap43-induced gene; Spider biofilm induced || 1 -0.03 -0.11 0.23 0.71 -0.99 -0.28 -0.29 -0.12 0.15 0.39 -0.86 -0.69 0.05 -0.38 -0.83 -1.72
6535 || orf19.4937 || CHS3 || || Major chitin synthase of yeast and hyphae; synthesizes short-chitin fibrils; Chs4-activated; transcript induced at yeast-hyphal transition; Chs1 and Chs2, but not Chs3, are inhibited by the protoberberine HWY-289; Spider biofilm induced || 1 0.08 -0.17 0.56 0.44 -1.11 -0.74 -0.47 -0.36 0.01 0.40 -0.76 -0.65 -0.31 -0.90 -0.41 -1.36
6536 || orf19.4022 || SDH4 || || Succinate dehydrogenase, membrane subunit; induced in high iron || 1 0.11 0.04 0.35 0.33 -0.76 -0.64 -0.41 -0.33 0.12 0.18 -0.59 -0.16 -0.31 -0.95 -0.84 -1.23
6537 || orf19.3740 || PGA23 || || Putative GPI-anchored protein of unknown function; Rim101-repressed; Cyr1-regulated; colony morphology-related gene regulation by Ssn6 || 1 0.12 0.07 0.94 1.16 -2.03 -1.69 -0.45 -0.35 0.17 -0.51 -2.01 -0.39 -1.45 -1.20 -2.23 -2.81
6538 || orf19.2890 || || || Has domain(s) with predicted sugar:hydrogen symporter activity, role in carbohydrate transport and Golgi membrane, integral to membrane localization || 1 -0.00 -0.04 0.13 0.52 -0.70 -0.41 -0.25 0.15 0.20 -0.03 -0.79 -0.05 -0.35 -0.27 -0.74 -0.79
6539 || orf19.3684 || || || Putative oxidoreductase; Spider biofilm induced || 1 -0.38 0.29 1.47 1.93 -1.35 -1.47 -1.09 -1.06 -1.43 0.38 -3.73 -1.18 0.47 -0.59 -2.26 -1.93
6540 || orf19.209 || DFG10 || || Ortholog(s) have role in dolichol biosynthetic process, dolichol-linked oligosaccharide biosynthetic process, polyprenol catabolic process, pseudohyphal growth and endoplasmic reticulum localization || 1 -0.31 -0.31 0.92 0.52 -0.40 -0.52 -0.26 -0.11 0.27 -0.36 -0.41 -0.64 0.10 -0.15 -0.96 -0.60
6541 || orf19.2285 || || || Protein of unknown function; transcription induced by benomyl treatment || 1 -0.12 -0.11 0.92 0.63 -0.39 -0.61 -0.47 -0.44 -0.07 -0.26 -0.55 -0.98 -0.04 -0.23 -0.53 -0.57
6542 || orf19.7631 || SLD5 || || Putative GINS complex subunit; cell-cycle regulated periodic mRNA expression || 1 0.02 0.05 0.85 0.57 -0.50 -0.61 -0.41 -0.34 0.14 -0.02 -0.34 -0.57 0.25 -0.55 -0.86 -0.38
6543 || orf19.1345 || LIP8 || || Secreted lipase, member of a differentially expressed lipase gene family with possible roles in nutrition and/or in creating an acidic microenvironment; LIP5 and LIP8 are expressed at all stages of both mucosal and systemic infection || 1 0.37 0.26 1.68 0.98 -1.14 -0.99 -0.69 -0.20 -0.25 -0.11 -0.62 -1.08 0.14 -0.80 -1.13 -1.21
6544 || orf19.2810 || AAP1 || || Putative amino acid permease; fungal-specific; possibly essential, disruptants not obtained by UAU1 method; Spider biofilm induced || 1 0.19 0.31 1.17 0.78 -0.67 -0.62 -0.07 -0.23 0.17 0.12 -0.54 -0.66 0.19 -0.20 -0.64 -0.41
6545 || orf19.6487 || || || Ortholog of C. parapsilosis CDC317 : CPAR2_808350, C. dubliniensis CD36 : Cd36_72060, Candida orthopsilosis Co 90-125 : CORT_0C00820 and Candida albicans WO-1 : CAWG_05575 || 1 1.17 1.54 0.38 1.16 -1.84 -0.70 -0.35 0.10 0.51 -0.34 -1.22 -0.32 -0.86 -0.47 -1.74 0.26
6546 || orf19.6486 || LDG3 || || Putative LDG family protein; F-12/CO2 early biofilm induced || 1 1.59 1.67 1.40 2.15 -2.05 -0.92 -0.22 -0.25 1.01 -0.34 -1.75 -1.05 -1.34 -1.34 -1.81 -0.35
6547 || orf19.6484 || || || Ortholog of C. parapsilosis CDC317 : CPAR2_808370, C. dubliniensis CD36 : Cd36_72070, Candida orthopsilosis Co 90-125 : CORT_0C00800 and Candida albicans WO-1 : CAWG_05577 || 1 1.75 1.50 1.00 2.11 -0.94 -0.58 0.01 0.22 1.49 -0.35 -1.77 -1.11 -0.45 -0.88 -1.23 -0.88
6548 || orf19.6486 || LDG3 || || Putative LDG family protein; F-12/CO2 early biofilm induced || 1 1.20 1.57 0.67 2.20 -0.75 -1.15 -0.63 -0.42 1.40 -0.51 -1.56 -0.60 -0.53 -0.39 -1.40 -0.75
6549 || orf19.1557 || || || Ortholog(s) have S-adenosylmethionine-dependent methyltransferase activity, role in protein methylation and cytosol, nucleus localization || 1 0.36 0.15 0.52 0.54 -0.06 -0.27 0.08 -0.09 0.05 0.03 -0.21 -0.22 -0.38 -0.07 -0.57 -0.21
6550 || orf19.689 || PLB1 || || Phospholipase B; host cell penetration and virulence in mouse systemic infection; Hog1-induced; signal sequence, N-glycosylation, and Tyr phosphorylation site; induced in fluconazole-resistant strains; rat catheter biofilm repressed || 1 1.44 1.26 2.23 2.16 -1.83 -1.61 -0.90 -0.43 -0.84 -0.65 -1.67 -2.79 -1.96 -1.17 -2.21 -0.98
6551 || orf19.689 || PLB1 || || Phospholipase B; host cell penetration and virulence in mouse systemic infection; Hog1-induced; signal sequence, N-glycosylation, and Tyr phosphorylation site; induced in fluconazole-resistant strains; rat catheter biofilm repressed || 1 1.53 1.55 2.56 1.84 -1.63 -1.27 -0.79 -0.31 -0.11 -0.38 -1.41 -1.27 -1.28 -0.59 -1.68 -0.29
6552 || orf19.689 || PLB1 || || Phospholipase B; host cell penetration and virulence in mouse systemic infection; Hog1-induced; signal sequence, N-glycosylation, and Tyr phosphorylation site; induced in fluconazole-resistant strains; rat catheter biofilm repressed || 1 1.18 1.12 2.52 2.43 -0.74 -1.02 -0.50 -0.39 -0.32 -0.45 -0.69 -1.72 -1.27 -0.85 -1.12 -0.40
6553 || orf19.689 || PLB1 || || Phospholipase B; host cell penetration and virulence in mouse systemic infection; Hog1-induced; signal sequence, N-glycosylation, and Tyr phosphorylation site; induced in fluconazole-resistant strains; rat catheter biofilm repressed || 1 1.54 1.67 2.27 2.17 -1.14 -1.54 -0.54 -0.38 -0.27 -0.69 -1.34 -1.56 -1.15 -1.86 -1.54 -1.12
6554 || orf19.6323 || HPA2 || || Ortholog(s) have D-amino-acid N-acetyltransferase activity, role in D-amino acid metabolic process and cytosol, nucleus localization || 1 0.87 0.87 1.42 1.63 -0.74 -1.00 -0.22 -0.21 0.07 -0.31 -0.60 -0.55 -0.60 -0.98 -0.43 -0.37
6555 || orf19.6323 || HPA2 || || Ortholog(s) have D-amino-acid N-acetyltransferase activity, role in D-amino acid metabolic process and cytosol, nucleus localization || 1 0.64 0.66 1.17 1.01 -1.20 -0.91 -0.12 -0.25 -0.16 -0.38 -0.64 -0.53 -0.99 -0.39 -0.37 -0.31
6556 || orf19.6758 || || || Predcted glucose 1-dehydrogenase (NADP+); rat catheter biofilm repressed || 1 0.80 0.73 1.04 0.83 -1.01 -0.54 0.08 -0.10 0.13 0.00 -0.88 -0.59 -0.60 -0.24 -0.57 -0.57
6557 || orf19.3516 || || || Protein of unknown function; Hap43-repressed; Spider biofilm repressed || 1 0.47 0.58 0.65 1.01 -0.61 -0.59 -0.12 -0.12 -0.43 0.07 -0.48 -0.39 -0.43 0.09 -0.36 -0.12
6558 || orf19.2462 || PRN3 || || Protein similar to pirin; induced by Mnl1 under weak acid stress; Hap43-repressed; Spider biofilm induced || 1 1.06 0.86 0.81 0.65 -0.81 -0.53 0.15 -0.22 -0.05 0.55 -1.50 -0.76 -0.48 0.54 -0.84 -0.81
6559 || orf19.3710 || YHB5 || || Flavohemoglobin-related protein; not required for normal NO resistance; predicted globin/FAD-binding/NAD(P)-binding domains but lacks some conserved residues of flavohemoglobins; filament induced; rat catheter and Spider biofilm induced || 1 1.51 1.07 0.83 0.81 -1.05 -0.93 -0.12 -0.40 0.11 0.50 -0.84 -0.80 -0.55 -0.27 -0.16 -0.44
6560 || orf19.6146 || CLG1 || || Putative cyclin-like protein; transcription is regulated upon yeast-hyphal switch || 1 0.56 0.54 0.18 0.44 -0.25 -0.77 -0.00 -0.50 0.05 0.32 -0.63 -0.35 -0.28 0.13 -0.49 -0.19
6561 || orf19.6146 || CLG1 || || Putative cyclin-like protein; transcription is regulated upon yeast-hyphal switch || 1 0.59 0.59 0.43 0.56 -0.26 -0.78 -0.00 -0.42 -0.15 0.22 -0.62 -0.35 -0.26 -0.25 -0.65 -0.25
6562 || orf19.6919 || || || Ortholog of C. dubliniensis CD36 : Cd36_71210, C. parapsilosis CDC317 : CPAR2_702710, Candida tenuis NRRL Y-1498 : CANTEDRAFT_116256 and Debaryomyces hansenii CBS767 : DEHA2E17732g || 1 1.31 1.29 1.11 1.31 -1.18 -1.37 -0.01 -0.79 0.41 0.74 -1.69 -0.84 -0.64 -0.73 -0.96 -1.33
6563 || orf19.6919 || || || Ortholog of C. dubliniensis CD36 : Cd36_71210, C. parapsilosis CDC317 : CPAR2_702710, Candida tenuis NRRL Y-1498 : CANTEDRAFT_116256 and Debaryomyces hansenii CBS767 : DEHA2E17732g || 1 1.37 1.12 0.46 1.20 -1.70 -1.44 0.12 -0.97 0.30 0.86 -2.09 -1.09 -0.71 -0.31 -1.25 -0.78
6564 || orf19.6919 || || || Ortholog of C. dubliniensis CD36 : Cd36_71210, C. parapsilosis CDC317 : CPAR2_702710, Candida tenuis NRRL Y-1498 : CANTEDRAFT_116256 and Debaryomyces hansenii CBS767 : DEHA2E17732g || 1 1.25 1.28 0.89 1.27 -1.49 -1.56 0.13 -0.79 0.34 0.68 -2.09 -1.01 -0.88 -0.45 -1.33 -0.53
6565 || orf19.6919 || || || Ortholog of C. dubliniensis CD36 : Cd36_71210, C. parapsilosis CDC317 : CPAR2_702710, Candida tenuis NRRL Y-1498 : CANTEDRAFT_116256 and Debaryomyces hansenii CBS767 : DEHA2E17732g || 1 1.09 1.12 0.82 1.16 -1.82 -1.49 0.03 -0.99 0.26 0.62 -1.90 -1.06 -1.15 -0.33 -0.93 -0.56
6566 || orf19.6919 || || || Ortholog of C. dubliniensis CD36 : Cd36_71210, C. parapsilosis CDC317 : CPAR2_702710, Candida tenuis NRRL Y-1498 : CANTEDRAFT_116256 and Debaryomyces hansenii CBS767 : DEHA2E17732g || 1 1.34 1.14 0.83 1.18 -2.02 -1.43 0.17 -1.05 0.07 0.62 -2.25 -1.09 -1.32 -0.78 -1.13 -0.37
6567 || orf19.4574 || || || Ortholog(s) have lipid particle localization || 1 0.45 0.33 0.52 0.68 -0.94 -0.68 -0.35 -0.55 -0.11 0.50 -1.03 -0.46 -0.47 -0.38 -1.01 -0.49
6568 || orf19.3121 || GST1 || || Putative glutathione S-transferase; upregulated in the presence of human neutrophils; expression is regulated upon white-opaque switching; increased transcription is observed upon benomyl treatment || 1 0.44 0.43 0.52 0.19 -2.26 -2.11 -0.15 -0.69 0.32 0.71 -2.62 -1.20 -1.99 -0.95 -1.95 -1.31
6569 || orf19.183 || HIS3 || || Imidazoleglycerol-phosphate dehydratase, enzyme of histidine biosynthesis; functionally complements S. cerevisiae his3-1 mutation; hyphal-induced expression; regulated by Gcn2p and Gcn4p; fungal-specific (no human or murine homolog) || 1 0.41 0.19 0.07 0.47 -1.76 -1.72 0.36 -0.25 -0.15 0.29 -1.20 -0.90 -1.00 0.30 -1.02 -0.96
6570 || orf19.5266 || || || Planktonic growth-induced gene || 1 0.12 0.25 0.21 0.24 -0.56 -0.72 0.22 -0.21 -0.05 0.15 -0.82 -0.55 -0.29 0.27 -0.45 -0.48
6571 || orf19.6376 || PTC5 || || Mitochondrial protein phosphatase of the Type 2C-related family (serine/threonine-specific), involved in drug response and cadmium tolerance || 1 0.44 0.37 0.55 0.46 -0.22 -0.09 -0.45 -0.41 0.19 0.19 -0.87 -0.31 -0.53 0.14 -0.38 -0.35
6572 || orf19.2285 || || || Protein of unknown function; transcription induced by benomyl treatment || 1 0.53 0.49 0.52 0.55 -0.52 -0.03 -0.59 -0.26 0.07 -0.03 -1.34 -0.11 -0.90 -0.15 -0.53 -0.41
6573 || orf19.5210 || || || Putative Xbp1 transcriptional repressor; binds to cyclin gene promoters in S. cerevisiae; Hap43-repressed; possibly essential, disruptants not obtained by UAU1 method || 1 1.12 1.04 0.55 0.97 -1.01 -0.58 -1.38 -0.90 -0.43 0.43 -1.32 -0.49 -2.54 -1.65 -1.71 -1.34
6574 || orf19.5210 || || || Putative Xbp1 transcriptional repressor; binds to cyclin gene promoters in S. cerevisiae; Hap43-repressed; possibly essential, disruptants not obtained by UAU1 method || 1 1.14 1.14 0.68 1.12 -0.73 -0.84 -0.80 -0.69 -0.47 0.12 -1.43 -1.05 -1.55 -1.52 -1.49 -1.35
6575 || orf19.5655 || || || Has domain(s) with predicted 2 iron, 2 sulfur cluster binding, iron ion binding, oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen and NAD(P)H as one donor, more || 1 0.25 0.37 0.89 0.85 -0.42 -0.14 -0.42 -0.48 0.50 0.34 -1.63 -1.07 -1.51 -1.42 -0.90 -1.00
6576 || orf19.2701 || || || Protein of unknown function; Ras1 and Cyr1 repressed; rat catheter and Spider biofilm induced || 1 1.29 1.10 1.46 0.74 -0.98 -1.34 -1.45 -1.21 0.79 0.15 -4.59 -2.13 -2.80 -2.01 -4.77 -3.08
6577 || orf19.2701 || || || Protein of unknown function; Ras1 and Cyr1 repressed; rat catheter and Spider biofilm induced || 1 0.98 0.96 1.37 1.11 -1.17 -1.19 -1.62 -1.58 0.70 0.30 -4.07 -1.87 -2.87 -1.47 -3.68 -2.86
6578 || orf19.5114 || || || Sorting nexin; role in maintaining late-Golgi resident enzymes in their proper location by recycling molecules from the prevacuolar compartment; Spider biofilm induced || 1 0.41 0.42 0.44 0.09 -0.75 -0.70 -0.61 -0.48 0.24 -0.28 -1.19 -1.08 -1.18 -0.41 -1.09 -0.40
6579 || orf19.3707 || YHB1 || || Nitric oxide dioxygenase; acts in nitric oxide scavenging/detoxification; role in virulence in mouse; transcript activated by NO, macrophage interaction; Hap43, hypha repressed; mRNA binds She3 || 1 1.31 1.45 1.26 -0.17 -1.00 -0.47 0.01 -0.23 0.75 -0.11 -2.24 -1.21 -0.97 -0.47 -2.25 -1.36
6580 || orf19.3707 || YHB1 || || Nitric oxide dioxygenase; acts in nitric oxide scavenging/detoxification; role in virulence in mouse; transcript activated by NO, macrophage interaction; Hap43, hypha repressed; mRNA binds She3 || 1 1.67 1.73 1.84 0.31 -0.87 -0.50 0.15 0.24 1.14 0.17 -2.12 -0.85 -0.66 -0.38 -2.22 -1.71
6581 || orf19.6707 || || || Predicted vacuolar protein with a calcineurin-like phosphoesterase domain; repressed by alpha pheromone in SpiderM medium || 1 0.78 0.79 0.72 0.35 -0.55 0.19 -0.54 -0.16 0.19 0.38 -0.87 -0.64 -0.54 -0.47 -0.67 -0.94
6582 || orf19.6707 || || || Predicted vacuolar protein with a calcineurin-like phosphoesterase domain; repressed by alpha pheromone in SpiderM medium || 1 1.09 0.93 0.67 0.50 -0.83 0.05 -0.46 -0.39 0.30 0.57 -1.35 -0.83 -0.26 -0.68 -1.18 -1.09
6583 || orf19.6707 || || || Predicted vacuolar protein with a calcineurin-like phosphoesterase domain; repressed by alpha pheromone in SpiderM medium || 1 1.10 1.12 0.74 0.76 -0.50 0.31 -0.38 -0.05 0.07 0.71 -1.45 -0.79 -0.29 -0.91 -1.20 -1.13
6584 || orf19.4591 || CAT2 || || Major carnitine acetyl transferase; intracellular acetyl-CoA transport; localized in peroxisomes and mitochondria; induced in macrophages; Hog1-repressed; stationary phase enriched; farnesol-upregulated in biofilm; Spider biofilm induced || 1 0.83 0.58 0.74 1.07 -0.36 -0.76 -0.40 0.22 -0.11 0.67 -1.49 -0.83 -0.82 -0.11 -1.12 -1.23
6585 || orf19.6443 || || || Protein with an enoyl-CoA hydratase related domain; Spider biofilm induced || 1 0.02 -0.14 0.52 0.84 -0.89 -0.68 -0.33 0.18 0.06 0.30 -1.82 -1.41 -0.95 -1.00 -1.15 -1.20
6586 || orf19.6443 || || || Protein with an enoyl-CoA hydratase related domain; Spider biofilm induced || 1 0.43 0.03 0.99 1.01 -0.68 -0.33 -0.28 0.15 0.08 0.56 -2.00 -1.17 -1.07 -0.65 -1.29 -1.26
6587 || orf19.6443 || || || Protein with an enoyl-CoA hydratase related domain; Spider biofilm induced || 1 0.20 0.04 0.60 0.56 -0.45 -0.51 -0.03 0.21 0.24 0.63 -1.92 -1.18 -1.00 -0.77 -0.83 -1.56
6588 || orf19.6443 || || || Protein with an enoyl-CoA hydratase related domain; Spider biofilm induced || 1 0.37 0.34 1.08 1.16 -0.52 -0.82 -0.37 0.33 0.40 0.61 -2.11 -1.64 -0.86 -1.20 -1.14 -2.42
6589 || orf19.6443 || || || Protein with an enoyl-CoA hydratase related domain; Spider biofilm induced || 1 0.30 0.29 1.06 0.73 -0.27 -0.42 0.12 0.19 0.22 0.42 -1.39 -1.28 -0.21 -0.68 -0.41 -1.56
6590 || orf19.3311 || IFD3 || || Putative aldo/keto reductase; Mig1-regulated || 1 -0.11 -0.21 0.46 0.93 -0.48 -0.91 -0.05 -0.04 0.18 0.07 -1.34 -1.08 -0.43 -0.10 -0.67 -1.30
6591 || orf19.3311 || IFD3 || || Putative aldo/keto reductase; Mig1-regulated || 1 -0.35 -0.35 0.24 0.45 -0.26 -0.77 -0.01 -0.09 -0.06 -0.08 -1.26 -0.69 -0.73 -0.05 -0.54 -0.79
6592 || orf19.1037 || || || Protein of unknown function; rat catheter biofilm repressed || 1 0.51 0.29 0.58 0.30 -1.31 -1.34 0.35 -0.16 -0.28 -0.58 -1.69 -1.27 -0.30 0.69 -1.47 -0.18
6593 || orf19.1037 || || || Protein of unknown function; rat catheter biofilm repressed || 1 0.50 0.33 0.61 0.42 -1.23 -1.42 0.06 -0.26 -0.28 -0.77 -1.70 -1.54 -0.39 0.45 -1.62 -0.36
6594 || orf19.1037 || || || Protein of unknown function; rat catheter biofilm repressed || 1 -0.01 0.14 0.85 0.40 -0.57 -0.61 0.05 -0.35 -0.01 -0.42 -1.32 -1.28 -0.23 0.73 -1.03 -0.40
6595 || orf19.1117 || || || Protein similar to Candida boidinii formate dehydrogenase; virulence-group-correlated expression; Hap43-repressed; Spider biofilm repressed || 1 0.76 0.78 1.65 1.81 -1.90 -1.18 0.05 -0.24 -0.95 -0.86 -2.84 -2.19 -0.91 0.41 -2.77 -1.69
6596 || orf19.1774 || || || Predicted dehydrogenase; transcript upregulated in an RHE model of oral candidiasis; virulence-group-correlated expression; Spider biofilm repressed || 1 0.57 0.54 1.45 2.24 -2.58 -2.40 0.18 -0.48 -1.99 -1.44 -3.25 -3.57 -1.71 0.33 -4.48 -3.08
6597 || orf19.1774 || || || Predicted dehydrogenase; transcript upregulated in an RHE model of oral candidiasis; virulence-group-correlated expression; Spider biofilm repressed || 1 0.57 0.56 1.76 2.17 -1.90 -1.88 -0.03 -0.60 -1.36 -1.43 -2.48 -2.97 -1.54 0.02 -3.47 -1.86
6598 || orf19.1117 || || || Protein similar to Candida boidinii formate dehydrogenase; virulence-group-correlated expression; Hap43-repressed; Spider biofilm repressed || 1 0.21 0.31 1.74 1.59 -1.60 -1.27 0.26 -0.53 -1.91 -1.51 -2.45 -2.81 -1.87 0.23 -3.77 -2.05
6599 || orf19.855 || || || Ortholog of C. dubliniensis CD36 : Cd36_18340, Candida tenuis NRRL Y-1498 : CANTEDRAFT_124631, Debaryomyces hansenii CBS767 : DEHA2D04356g and Pichia stipitis Pignal : PICST_34839 || 1 0.06 -0.02 0.25 0.73 -0.89 -1.62 -0.37 -0.55 -0.33 -0.99 -1.50 -2.43 0.28 -0.49 -1.36 -1.78
6600 || orf19.640 || || || Integral membrane protein of the ER; role in the synthesis of beta-1,6-glucan in the cell wall; S. cerevisiae ortholog required for cell viability; Spider biofilm induced || 1 -0.34 -0.40 0.62 0.78 -0.93 -0.79 -0.70 -0.63 -0.59 -0.27 -0.28 -0.53 -0.90 -0.57 -0.88 -0.54
6601 || orf19.2313 || || || Putative ortholog of S. cerevisiae Pex32 a peroxisomal integral membrane protein with a role in negative regulation of peroxisome size; Hap43-repressed gene || 1 -0.44 -0.38 0.31 0.67 -1.05 -0.52 -0.67 -0.54 -0.17 -0.30 -0.50 -0.47 -0.51 -0.43 -0.54 -0.64
6602 || orf19.5886 || CUP5 || || Putative proteolipid subunit of the vacuolar H(+)-ATPase V0 sector; required for vacuolar acidification, secretion, filamentous growth; caspofungin repressed || 1 -0.10 -0.18 0.31 0.60 -1.46 -1.09 -0.49 -0.35 -0.46 -0.48 -0.43 -0.30 -0.12 -0.44 -1.02 -0.70
6603 || orf19.5886 || CUP5 || || Putative proteolipid subunit of the vacuolar H(+)-ATPase V0 sector; required for vacuolar acidification, secretion, filamentous growth; caspofungin repressed || 1 -0.37 -0.43 0.27 0.55 -1.70 -0.96 -0.68 -0.53 -0.48 -0.43 -0.56 -0.28 -0.72 -0.46 -1.13 -0.32
6604 || orf19.4922 || || || Ortholog(s) have Rab GTPase binding activity and Golgi apparatus, endoplasmic reticulum localization || 1 -0.12 -0.31 0.52 0.27 -1.49 -1.33 -0.68 -0.43 -0.31 -0.18 -0.77 -0.78 -0.76 -0.34 -1.27 -0.78
6605 || orf19.2350 || || || Protein similar to S. cerevisiae Yor378w; MFS family transporter; transposon mutation affects filamentous growth; null mutants are viable; fungal-specific (no human or murine homolog) || 1 -0.11 -0.21 0.84 0.78 -1.83 -1.14 -0.87 -0.66 -0.33 -0.32 -1.04 -0.75 -1.02 0.08 -1.03 -0.31
6606 || orf19.656 || DPP1 || || Putative diacylglycerol pyrophosphate phosphatase of diacylglycerol production for phospholipid biosynthesis; downregulation correlates with clinical development of fluconazole resistance || 1 0.14 -0.05 0.80 1.17 -1.92 -1.19 -0.92 -0.57 -0.49 -0.50 -1.43 -0.23 -1.39 -1.55 -0.37
6607 || orf19.2761 || || || Putative glycosylphosphatidylinositol (GPI) anchor assembly protein; transposon insertion causes decreased colony wrinkling but does not block true hyphal growth; induced by nitric oxide independent of Yhb1p || 1 0.02 -0.09 0.44 0.50 -1.17 -0.69 -0.66 -0.10 0.04 0.26 -0.67 -0.30 -0.84 0.01 -1.19 -0.38
6608 || orf19.7089 || PMR1 || || Putative secretory pathway P-type Ca2+/Mn2+-ATPase; required for protein glycosylation and cell wall maintenance; required for hyphal tip oscillation in semisolid substrate; putative ortholog of S. cerevisiae PMR1 || 1 -0.04 -0.44 0.31 0.64 -1.43 -0.84 -0.38 -0.13 -0.15 0.15 -0.76 -0.28 -0.82 -0.36 -1.35 -0.47
6609 || orf19.4845 || TVP18 || || Putative integral membrane protein; fluconazole-induced || 1 -0.02 -0.09 0.36 0.58 -0.84 -0.40 -0.82 -0.28 -0.33 0.11 -0.37 -0.11 -0.98 0.01 -0.94 -0.17
6610 || orf19.2571 || SEC4 || || Small GTPase of Rab family; role in post-Golgi secretion; possible C-terminal palmitoylation; downregulated on adherence to polystyrene; localizes to the Spitzenkorper during hyphal growth; functional homolog of S. cerevisiae Sec4p || 1 0.11 -0.09 0.42 0.50 -0.59 -0.38 -0.36 0.17 -0.05 0.00 -0.30 -0.09 -0.35 -0.22 -0.50 -0.36
6611 || orf19.656 || DPP1 || || Putative diacylglycerol pyrophosphate phosphatase of diacylglycerol production for phospholipid biosynthesis; downregulation correlates with clinical development of fluconazole resistance || 1 0.41 0.25 0.75 1.17 -1.02 -1.03 -0.70 -0.05 0.03 -0.25 -0.77 0.09 -1.09 -0.33 -0.80 -0.13
6612 || orf19.656 || DPP1 || || Putative diacylglycerol pyrophosphate phosphatase of diacylglycerol production for phospholipid biosynthesis; downregulation correlates with clinical development of fluconazole resistance || 1 0.36 0.68 0.83 1.04 -1.21 -1.01 -0.54 -0.24 0.27 0.08 -0.84 -0.11 -0.35 -0.54 -0.80 -0.23
6613 || orf19.5303 || PGA30 || || GPI-anchored protein of cell wall || 1 1.45 1.25 1.36 1.83 -2.64 -2.70 -0.42 -0.51 -0.18 -0.13 -1.45 -0.82 -1.39 -1.33 -1.74 -0.69
6614 || orf19.308 || || || Ortholog(s) have role in nucleobase-containing compound transport and plasma membrane localization || 1 1.19 1.03 0.84 1.36 -2.57 -1.78 -1.36 -1.22 -0.68 -0.29 -1.13 -0.29 -0.96 -0.34 -1.69 -0.55
6615 || orf19.656 || DPP1 || || Putative diacylglycerol pyrophosphate phosphatase of diacylglycerol production for phospholipid biosynthesis; downregulation correlates with clinical development of fluconazole resistance || 1 0.46 -0.02 0.95 1.36 -1.04 -0.99 -0.45 -0.56 -0.35 -0.18 -0.51 -0.07 -0.96 -0.73 -1.08 -0.56
6616 || orf19.2187 || ALG7 || || Protein involved in cell wall mannan biosynthesis; mutation confers hypersensitivity to tunicamycin; transcript elevated in chk1, nik1, and sln1 homozygous null mutants; possibly essential gene, disruptants not obtained by UAU1 method || 1 0.40 0.22 0.81 1.04 -1.63 -1.30 -1.12 -0.47 -0.27 -0.04 -0.62 -0.64 -1.44 -0.89 -1.74 -0.87
6617 || orf19.2187 || ALG7 || || Protein involved in cell wall mannan biosynthesis; mutation confers hypersensitivity to tunicamycin; transcript elevated in chk1, nik1, and sln1 homozygous null mutants; possibly essential gene, disruptants not obtained by UAU1 method || 1 0.79 0.73 0.99 1.20 -0.97 -1.06 -0.75 -0.37 -0.10 0.01 -0.37 -0.45 -1.52 -0.50 -1.70 -0.66
6618 || orf19.7049 || CYB5 || || Cytochrome b(5); ortholog of S. cerevisiae Cyb5; induced in high iron; fluconazole-induced; shows colony morphology-related gene regulation by Ssn6; mutants are viable || 1 0.98 0.83 0.51 0.88 -2.48 -2.12 -0.75 -0.12 -0.48 0.44 -0.57 -0.12 -2.05 -0.87 -2.14 -1.13
6619 || orf19.1212 || || || Ortholog(s) have FFAT motif binding, phosphatidylinositol binding activity || 1 0.68 0.69 0.97 1.60 -2.38 -2.19 -0.68 -0.31 -0.68 -0.17 -0.79 -0.52 -0.41 0.00 -1.06 -0.98
6620 || orf19.5137.1 || HHO1 || || Putative histone H1; farnesol regulated; Hap43-induced; contains 5' UTR intron; Spider biofilm repressed || 1 0.14 0.09 0.67 0.86 -2.04 -1.48 -0.66 -0.63 -0.54 -0.45 -0.76 -0.21 0.23 -0.15 -0.69 -0.29
6621 || orf19.1115 || GUK1 || || Putative guanylate kinase; identified in extracts from biofilm and planktonic cells; protein level decrease in stationary phase cultures; Hap43p-induced gene || 1 0.17 0.08 0.83 0.54 -1.95 -1.76 -0.89 -0.74 -0.50 0.00 -1.07 -0.76 0.18 0.12 -0.96 -1.00
6622 || orf19.4845 || TVP18 || || Putative integral membrane protein; fluconazole-induced || 1 0.79 0.68 -0.17 0.26 -2.25 -1.32 -0.91 -0.76 -1.04 -0.56 -1.80 -0.94 0.30 -0.32 -2.09 -1.38
6623 || orf19.3535 || || || Ortholog(s) have cellular bud neck, fungal-type vacuole localization || 1 0.35 0.19 0.32 0.41 -1.34 -0.97 -0.70 -0.49 -0.88 -0.14 -1.07 -0.96 0.03 -0.03 -1.03 -0.79
6624 || orf19.7218 || RBE1 || || Pry family cell wall protein; Rim101, Efg1, Ssn6, alkaline repressed; O-glycosylation; no GPI anchor predicted; ketoconazol induced; regulated by Sef1, Sfu1, Hap4; flow model biofilm induced; rat catheter and Spider biofilm repressed || 1 1.10 0.95 1.60 1.77 -4.75 -2.03 -1.73 -1.34 -1.42 -2.07 -2.38 -1.95 0.33 -0.30 -3.28 -1.70
6625 || orf19.7218 || RBE1 || || Pry family cell wall protein; Rim101, Efg1, Ssn6, alkaline repressed; O-glycosylation; no GPI anchor predicted; ketoconazol induced; regulated by Sef1, Sfu1, Hap4; flow model biofilm induced; rat catheter and Spider biofilm repressed || 1 1.08 0.85 1.49 1.64 -4.69 -2.24 -1.68 -1.35 -1.55 -2.17 -3.01 -1.78 0.09 -0.18 -3.56 -1.47
6626 || orf19.7151 || || || Ortholog of Candida albicans WO-1 : CAWG_05751 || 1 0.93 0.67 1.87 1.36 -3.28 -1.54 -1.29 -1.26 -0.22 -1.37 -2.11 -1.64 -1.05 0.09 -2.93 -0.41
6627 || orf19.6678 || || || Protein of unknown function; Hap43-repressed gene || 1 1.29 1.26 1.97 2.17 -4.07 -1.12 -1.30 -1.18 -1.21 -3.03 -2.45 -1.72 -0.68 -2.90 -1.64
6628 || orf19.7199 || || || Ortholog(s) have TRC complex, nucleus localization || 1 0.07 -0.09 1.01 0.71 -1.54 -0.32 -0.62 -0.91 -0.64 -1.12 -1.29 -0.61 -0.39 -0.45 -1.49 -0.31
6629 || orf19.5024 || GND1 || || 6-phosphogluconate dehydrogenase; soluble in hyphae; farnesol, macrophage-induced protein; antigenic in mice; dual localization to cytosol and peroxisomes depends on alternative splicing; rat catheter and Spider biofilm repressed || 1 -0.10 -0.05 0.34 0.62 -0.93 -0.42 -0.69 -0.77 -0.56 -0.53 -0.87 -0.35 0.06 -0.11 -0.75 -0.41
6630 || orf19.5112 || TKL1 || || Putative transketolase; localizes to surface of yeast cells, not hyphae; soluble protein in hyphae; transcript regulated by Nrg1, Mig1, and Tup1; antigenic in human or murine infection; possibly essential (by UAU1 method) || 1 0.30 0.24 -1.03 -0.84 -0.50 -0.57 -0.04 -0.54 -0.72 -0.73 0.10 -0.10 -0.55 -0.67
6631 || orf19.5462 || || || Protein of unknown function || 1 0.56 0.29 1.31 1.30 -2.15 -0.98 -0.58 -0.56 -0.25 -0.50 -1.06 -1.04 0.08 0.36 -1.17 -1.36
6632 || orf19.7495 || || || Protein with NADPH oxidoreductase containing flavin mononucleotide (FMN) domain; induced by nitric oxide || 1 0.33 0.41 1.70 1.79 -1.57 -1.10 -0.72 -0.20 -0.51 -0.34 -1.01 -1.11 0.26 1.13 -1.09 -0.98
6633 || orf19.7495 || || || Protein with NADPH oxidoreductase containing flavin mononucleotide (FMN) domain; induced by nitric oxide || 1 0.46 0.33 0.74 1.06 -0.75 -0.48 -0.51 -0.15 -0.29 -0.29 -0.65 -0.71 -0.30 0.36 -0.89 -0.34
6634 || orf19.1345 || LIP8 || || Secreted lipase, member of a differentially expressed lipase gene family with possible roles in nutrition and/or in creating an acidic microenvironment; LIP5 and LIP8 are expressed at all stages of both mucosal and systemic infection || 1 0.51 0.66 1.73 0.70 -1.63 -1.29 -0.74 -0.30 0.23 -0.38 -1.69 -0.87 -0.20 -0.43 -1.44 -0.41
6635 || orf19.6306 || || || Trimethylaminobutyraldehyde dehydrogenase, the third enzyme of the carnitine biosynthesis pathway || 1 0.75 0.59 0.72 1.02 -1.31 -2.27 -0.09 -0.05 0.50 -0.07 -1.33 -0.84 -0.67 -0.23 -2.12 -1.67
6636 || orf19.1814 || STT4 || || Putative phosphatidylinositol-4-kinase || 1 0.24 0.12 0.59 0.92 -0.88 -1.27 -0.07 -0.04 0.12 -0.34 -0.49 -0.51 -0.48 -0.29 -0.89 -0.63
6637 || orf19.183 || HIS3 || || Imidazoleglycerol-phosphate dehydratase, enzyme of histidine biosynthesis; functionally complements S. cerevisiae his3-1 mutation; hyphal-induced expression; regulated by Gcn2p and Gcn4p; fungal-specific (no human or murine homolog) || 1 0.31 0.19 0.73 1.09 -1.29 -1.09 0.18 -0.30 -0.09 0.23 -1.07 -0.68 -0.55 -0.12 -1.13 -0.65
6638 || orf19.183 || HIS3 || || Imidazoleglycerol-phosphate dehydratase, enzyme of histidine biosynthesis; functionally complements S. cerevisiae his3-1 mutation; hyphal-induced expression; regulated by Gcn2p and Gcn4p; fungal-specific (no human or murine homolog) || 1 0.32 0.13 0.92 1.00 -0.68 -1.18 0.26 -0.14 -0.09 0.14 -1.14 -0.69 -0.80 0.08 -0.97 -0.55
6639 || orf19.6306 || || || Trimethylaminobutyraldehyde dehydrogenase, the third enzyme of the carnitine biosynthesis pathway || 1 0.66 0.78 1.13 1.75 -1.27 -1.74 0.03 -0.13 0.43 -0.17 -1.51 0.03 -0.45 0.01 -1.39 -0.66
6640 || orf19.856 || IFK2 || || Putative thiol-specific monooxygenase; mutant is viable; flow model biofilm induced || 1 0.17 0.17 0.92 1.26 -1.75 -1.97 -0.16 0.06 -0.11 -0.33 -1.42 -1.12 -0.16 0.07 -1.11 -0.50
6641 || orf19.856 || IFK2 || || Putative thiol-specific monooxygenase; mutant is viable; flow model biofilm induced || 1 0.26 0.27 0.92 1.25 -0.94 -1.34 0.24 0.36 0.08 -0.25 -0.70 -0.66 -0.05 0.14 -0.41 -0.24
6642 || orf19.5619 || || || Protein of unknown function; induced by alpha pheromone in SpiderM medium; Spider biofilm induced || 1 0.04 0.19 0.39 0.62 -0.12 -0.76 -0.04 -0.11 -0.05 -0.13 -0.40 -0.33 0.01 0.06 -0.39 -0.27
6643 || orf19.5172 || LIP9 || || Secreted lipase, member of a lipase gene family whose members are expressed differentially in response to carbon source and during infection; may have a role in nutrition and/or in creating an acidic microenvironment || 1 0.05 -0.11 0.62 1.14 -0.80 -1.27 -0.67 -0.59 0.05 -0.29 -0.96 -1.13 -0.40 0.06 -1.17 -1.02
6644 || orf19.7151 || || || Ortholog of Candida albicans WO-1 : CAWG_05751 || 1 0.51 0.73 1.05 0.78 -0.92 -1.56 -1.22 -0.93 -0.26 -0.87 -1.99 -0.22 -0.73 -0.31 -1.51 -0.70
6645 || orf19.7500 || PXA1 || || Putative peroxisomal, half-size adrenoleukodystrophy protein (ALD or ALDp) subfamily ABC family transporter || 1 0.40 0.40 0.59 0.69 -0.65 -1.08 -1.08 -0.61 -0.31 0.11 -1.11 -0.54 -0.30 -0.27 -0.71 -0.75
6646 || orf19.5255 || PXA2 || || Putative peroxisomal, half-size adrenoleukodystrophy protein (ALD or ALDp) subfamily ABC transporter; Gcn4p-regulated || 1 -0.04 -0.20 0.61 1.06 -0.81 -0.87 -1.12 -1.02 -0.73 -0.53 -1.10 -0.56 -0.49 -0.52 -0.79 -0.74
6647 || orf19.5255 || PXA2 || || Putative peroxisomal, half-size adrenoleukodystrophy protein (ALD or ALDp) subfamily ABC transporter; Gcn4p-regulated || 1 0.27 -0.10 0.61 0.98 -0.66 -0.77 -0.86 -0.91 -0.41 -0.32 -0.97 -0.43 -0.47 -0.47 -0.42 -0.61
6648 || orf19.707 || APG7 || || Ortholog(s) have APG12 activating enzyme activity, APG8 activating enzyme activity || 1 0.12 0.19 0.61 0.74 -0.25 -0.60 -0.70 -0.72 -0.35 -0.27 -0.92 -0.54 -0.58 -0.50 -0.19 -0.16
6649 || orf19.6681 || || || Protein of unknown function; Spider biofilm induced || 1 0.33 0.15 0.81 0.93 -0.71 -0.49 -1.33 -1.38 -0.94 0.01 -1.74 -0.99 -1.01 -0.55 -1.07 -0.43
6650 || orf19.783 || || || Ortholog(s) have role in endocytosis, retrograde vesicle-mediated transport, Golgi to ER, vacuole organization and COPI-coated vesicle, Golgi membrane, endosome localization || 1 -0.12 -0.04 0.33 0.43 -0.32 -0.71 -0.88 -0.71 -0.33 -0.03 -1.03 -0.62 -0.62 -0.49 -0.86 -1.10
6651 || orf19.6126 || KGD2 || || Putative dihydrolipoamide S-succinyltransferase; induced in high iron; Hap43-repressed; Spider biofilm repressed || 1 0.24 0.27 0.20 0.40 -0.50 -0.41 -0.26 -0.26 -0.65 0.17 -1.39 -1.28 -0.73 -0.94 -0.48 -1.03
6652 || orf19.1308 || || || Predicted membrane transporter, member of the drug:proton antiporter (14 spanner) (DHA2) family, major facilitator superfamily (MFS) || 1 0.18 0.20 0.29 0.56 -0.56 -0.68 -0.64 -0.27 -0.60 0.09 -0.98 -0.81 -0.32 0.15 -0.55 -0.83
6653 || orf19.4591 || CAT2 || || Major carnitine acetyl transferase; intracellular acetyl-CoA transport; localized in peroxisomes and mitochondria; induced in macrophages; Hog1-repressed; stationary phase enriched; farnesol-upregulated in biofilm; Spider biofilm induced || 1 0.17 0.14 0.25 0.57 -0.96 -1.39 -0.48 -0.07 -0.74 0.20 -1.60 -1.18 -1.15 -0.34 -1.25 -1.41
6654 || orf19.5711 || || || Putative phosphatidylinositol transfer protein; possibly an essential gene, disruptants not obtained by UAU1 method || 1 0.32 0.47 0.68 1.24 -1.23 -1.48 -0.37 -0.17 -0.56 0.23 -0.74 -0.59 -0.95 -0.07 -1.16 -0.48
6655 || orf19.2452 || || || Protein of unknown function; induced in high iron; repressed in core caspofungin response; ketoconazole-repressed; colony morphology-related gene regulation by Ssn6; possibly subject to Kex2 processing || 1 0.96 0.93 0.68 1.75 -1.54 -1.94 -0.33 -0.10 -0.49 0.57 -0.60 -0.96 -0.61 -0.59 -1.62 -1.00
6656 || orf19.5723 || POX1 || || Predicted acyl-CoA oxidase; regulated upon white-opaque switch; upregulated upon phagocytosis; Spider biofilm induced || 1 0.64 0.68 0.71 1.04 -1.65 -2.09 -0.39 -0.02 -0.49 0.49 -0.68 -0.84 -0.96 -0.46 -1.35 -0.88
6657 || orf19.2452 || || || Protein of unknown function; induced in high iron; repressed in core caspofungin response; ketoconazole-repressed; colony morphology-related gene regulation by Ssn6; possibly subject to Kex2 processing || 1 1.12 1.05 0.38 1.28 -2.45 -2.59 -0.11 -0.14 -0.62 0.31 -0.72 -1.45 -0.57 -0.50 -2.31 -1.10
6658 || orf19.5723 || POX1 || || Predicted acyl-CoA oxidase; regulated upon white-opaque switch; upregulated upon phagocytosis; Spider biofilm induced || 1 1.30 1.33 1.04 1.36 -2.32 -2.30 -0.69 -0.22 -1.17 0.28 -2.06 -1.89 -1.01 -0.95 -2.19 -1.75
6659 || orf19.5723 || POX1 || || Predicted acyl-CoA oxidase; regulated upon white-opaque switch; upregulated upon phagocytosis; Spider biofilm induced || 1 1.17 1.23 1.28 1.61 -2.22 -2.42 -0.83 -0.25 -0.73 0.41 -1.96 -1.63 -1.32 -0.79 -1.87 -1.86
6660 || orf19.5723 || POX1 || || Predicted acyl-CoA oxidase; regulated upon white-opaque switch; upregulated upon phagocytosis; Spider biofilm induced || 1 1.48 1.47 1.59 1.77 -2.83 -2.77 -0.68 -0.31 -0.98 0.34 -1.74 -1.67 -1.15 -0.94 -2.38 -1.91
6661 || orf19.5723 || POX1 || || Predicted acyl-CoA oxidase; regulated upon white-opaque switch; upregulated upon phagocytosis; Spider biofilm induced || 1 1.13 1.12 1.24 1.82 -1.55 -1.73 -0.77 -0.31 -0.50 0.51 -1.50 -1.53 -1.08 -0.96 -1.60 -1.19
6662 || orf19.5921 || || || Ortholog(s) have glyoxysome localization || 1 0.70 0.58 1.12 1.64 -1.56 -1.82 -0.58 -0.04 -0.32 0.43 -1.51 -1.47 -1.31 -0.29 -1.25 -1.55
6663 || orf19.5157 || || || Protein with a protein tyrosine phosphatase-like protein domain; putative membrane-spanning regions; rat catheter biofilm induced || 1 0.90 0.83 0.51 1.10 -1.55 -1.70 -0.46 0.49 -0.62 0.20 -1.19 -1.30 -1.28 -0.44 -2.06 -1.44
6664 || orf19.5157 || || || Protein with a protein tyrosine phosphatase-like protein domain; putative membrane-spanning regions; rat catheter biofilm induced || 1 0.85 0.93 0.68 1.11 -1.60 -1.61 -0.32 0.73 -0.27 0.52 -1.15 -1.06 -1.19 -0.40 -1.96 -1.09
6665 || orf19.5921 || || || Ortholog(s) have glyoxysome localization || 1 0.89 0.58 0.33 0.73 -2.08 -2.40 -0.20 0.21 -0.58 0.49 -1.88 -1.96 -1.11 -0.30 -1.62 -2.08
6666 || orf19.4157 || SPS20 || || Peroxisomal 2,4-dienoyl-CoA reductase; stationary phase enriched protein; Spider biofilm induced || 1 0.46 0.37 0.94 1.31 -2.13 -2.44 -0.74 0.16 -0.75 0.39 -1.93 -1.60 -1.05 -0.47 -2.08 -1.95
6667 || orf19.4157 || SPS20 || || Peroxisomal 2,4-dienoyl-CoA reductase; stationary phase enriched protein; Spider biofilm induced || 1 0.12 0.38 0.78 1.43 -2.02 -2.70 -0.61 0.09 -0.97 0.46 -1.91 -1.62 -0.99 -0.58 -1.94 -1.92
6668 || orf19.854 || UGA11 || || Putative gamma-aminobutyrate (GABA) transaminase; macrophage-induced; overlaps orf19.854.1, which is a region annotated as a blocked reading frame; Spider biofilm induced || 1 0.43 0.55 1.10 1.54 -1.62 -2.59 -0.23 -0.02 -0.76 1.16 -2.00 -1.84 -0.25 -0.79 -1.86 -2.13
6669 || orf19.854 || UGA11 || || Putative gamma-aminobutyrate (GABA) transaminase; macrophage-induced; overlaps orf19.854.1, which is a region annotated as a blocked reading frame; Spider biofilm induced || 1 0.45 0.35 0.44 1.24 -1.74 -3.16 -0.36 0.07 -0.93 1.05 -2.10 -2.27 -0.40 -0.67 -2.16 -2.36
6670 || orf19.854 || UGA11 || || Putative gamma-aminobutyrate (GABA) transaminase; macrophage-induced; overlaps orf19.854.1, which is a region annotated as a blocked reading frame; Spider biofilm induced || 1 0.81 0.72 1.02 1.68 -1.94 -3.62 -0.10 0.44 -0.55 1.00 -2.10 -2.88 0.16 -0.95 -2.38 -3.04
6671 || orf19.3924 || || || Ortholog of Candida albicans WO-1 : CAWG_04810 || 1 0.64 0.68 0.68 2.00 -2.35 -4.48 -0.29 -0.28 -0.38 0.62 -2.58 -3.61 -0.59 -1.14 -2.58 -2.80
6672 || orf19.3924 || || || Ortholog of Candida albicans WO-1 : CAWG_04810 || 1 0.89 0.97 1.23 2.09 -3.20 -0.35 0.08 -0.39 1.12 -2.23 -3.56 -0.87 -0.87 -2.21 -2.44
6673 || orf19.4933 || FAD3 || || Omega-3 fatty acid desaturase; production of alpha-linolenic acid, a major component of membranes; caspofungin induced; Plc1-regulated; colony morphology-related gene regulation by Ssn6; Spider biofilm induced, flow model biofilm repressed || 1 0.53 0.85 0.64 1.50 -1.37 -1.66 -0.38 0.04 -0.84 0.58 -0.86 -1.91 -0.68 -0.11 -1.00 -1.92
6674 || orf19.2247 || || || Ortholog of C. parapsilosis CDC317 : CPAR2_406700, C. dubliniensis CD36 : Cd36_21220, Candida tenuis NRRL Y-1498 : CANTEDRAFT_127772 and Candida orthopsilosis Co 90-125 : CORT_0C06120 || 1 1.33 1.63 0.77 2.12 -1.80 -2.50 -0.10 -0.64 -0.22 0.97 -2.68 -3.58 -1.56 -1.66 -1.79 -3.16
6675 || orf19.2247 || || || Ortholog of C. parapsilosis CDC317 : CPAR2_406700, C. dubliniensis CD36 : Cd36_21220, Candida tenuis NRRL Y-1498 : CANTEDRAFT_127772 and Candida orthopsilosis Co 90-125 : CORT_0C06120 || 1 1.59 1.81 1.62 2.45 -1.57 -3.31 -0.51 -0.53 -0.10 0.97 -2.09 -1.38 -1.79 -2.44 -2.54
6676 || orf19.6784 || PGA32 || || Putative GPI-anchored adhesin-like protein; induced in high iron; Spider biofilm induced || 1 0.41 0.83 1.05 1.62 -0.79 -1.87 -0.60 -0.18 -0.44 0.54 -1.12 -1.65 -0.19 -1.06 -0.90 -2.05
6677 || orf19.6998 || GTT1 || || Putative glutathione S-transferase; downregulated upon adherence to polystyrene; regulated upon white-opaque switching; induced in the presence of human neutrophils; oxidative stress-induced via Cap1p; regulated by Gcn2p, Gcn4p || 1 0.88 0.80 0.87 2.28 -1.15 -1.48 -0.58 -0.02 -0.40 0.59 -1.31 -2.53 -0.67 -0.79 -0.99 -2.72
6678 || orf19.2253 || || || Protein of unknown function; expression regulated by white-opaque switch; repressed by alpha pheromone in SpiderM medium; Spider biofilm induced || 1 1.47 1.24 1.64 2.65 -2.02 -2.40 -0.63 -0.40 -1.01 0.13 -2.16 -3.93 -0.29 -1.13 -2.19 -2.60
6679 || orf19.2253 || || || Protein of unknown function; expression regulated by white-opaque switch; repressed by alpha pheromone in SpiderM medium; Spider biofilm induced || 1 0.87 0.56 1.44 2.19 -1.37 -2.93 -0.53 -0.56 -0.98 0.38 -2.05 -3.40 -0.23 -1.02 -1.10 -1.85
6680 || orf19.2199 || PHO86 || || Putative endoplasmic reticulum protein; possibly adherence-induced || 1 0.69 0.45 0.40 0.87 -1.56 -1.22 -0.19 -0.15 -0.48 -0.11 -0.98 -0.82 -0.35 -0.71 -0.88 -1.44
6681 || orf19.6678 || || || Protein of unknown function; Hap43-repressed gene || 1 1.76 1.78 2.26 2.68 -3.80 -5.99 -0.76 -0.78 -0.60 -1.40 -2.49 -4.01 -1.42 -0.92 -2.63 -3.01
6682 || orf19.6758 || || || Predcted glucose 1-dehydrogenase (NADP+); rat catheter biofilm repressed || 1 0.66 0.56 0.78 1.05 -1.28 -0.99 0.04 -0.06 0.26 -0.17 -0.95 -0.97 -0.51 -0.44 -0.94 -1.20
6683 || orf19.935 || AGA1 || || Protein with some similarity to agglutinin subunit; expression regulated upon white-opaque switch; Spider biofilm induced || 1 0.33 0.35 0.70 1.80 -1.79 -2.20 -0.41 -0.46 0.31 0.38 -1.17 -2.00 0.24 -1.41 -2.09 -1.72
6684 || orf19.935 || AGA1 || || Protein with some similarity to agglutinin subunit; expression regulated upon white-opaque switch; Spider biofilm induced || 1 0.71 0.71 1.31 2.42 -2.12 -4.89 -0.68 -1.23 0.06 0.22 -2.47 -4.29 0.49 -2.12 -2.93 -3.75
6685 || orf19.5302 || PGA31 || || Cell wall protein; putative GPI anchor; expression regulated upon white-opaque switch; induced by Congo Red and cell wall regeneration; Bcr1-repressed in RPMI a/a biofilms || 1 0.19 0.29 0.71 1.65 -2.25 -3.08 -1.46 -0.45 -0.53 0.28 -2.23 -3.71 -2.20 -1.99 -1.92 -2.88
6686 || orf19.7336 || || || Predicted membrane transporter; member of the drug:proton antiporter (14 spanner) (DHA2) family, major facilitator superfamily (MFS); Spider biofilm induced || 1 2.29 2.28 2.90 3.18 -6.12 -6.32 -4.82 -6.22 -2.68 -2.88 -6.47 -4.74 -3.18 -5.82 -5.72 -6.02
6687 || orf19.7336 || || || Predicted membrane transporter; member of the drug:proton antiporter (14 spanner) (DHA2) family, major facilitator superfamily (MFS); Spider biofilm induced || 1 2.17 2.13 2.63 3.16 -6.96 -6.11 -5.66 -6.77 -3.23 -3.62 -7.05 -8.75 -3.59 -6.20 -6.62 -5.44
6688 || orf19.7597 || PGA12 || || Putative GPI-anchored protein || 1 2.08 1.81 2.42 2.80 -5.48 -5.76 -4.39 -5.03 -5.05 -6.37 -5.75 -2.53 -6.12 -6.31 -4.64
6689 || orf19.7597 || PGA12 || || Putative GPI-anchored protein || 1 1.72 1.62 2.57 2.95 -5.33 -4.87 -5.35 -5.28 -4.75 -5.35 -6.61 -6.83 -2.54 -5.17 -6.59 -6.71
6690 || orf19.7597 || PGA12 || || Putative GPI-anchored protein || 1 1.64 1.51 2.37 2.65 -5.02 -5.47 -5.72 -5.74 -4.04 -4.05 -6.95 -5.89 -2.70 -4.77 -6.62 -5.69
6691 || orf19.6001 || SAP3 || || Secreted aspartyl proteinase, acts in utilization of protein as nitrogen source; assessment of virulence role complicated by URA3 effects; regulated by growth phase; produced by opaque phase cells; alpha-pheromone repressed || 1 3.06 -6.93 -6.59 -5.84 -6.25 -5.05 -5.39 -7.42 -6.87 -4.50 -6.32 -7.18 -6.85
6692 || orf19.6001 || SAP3 || || Secreted aspartyl proteinase, acts in utilization of protein as nitrogen source; assessment of virulence role complicated by URA3 effects; regulated by growth phase; produced by opaque phase cells; alpha-pheromone repressed || 1 -7.55 -7.14 -5.85 -6.42 -5.79 -5.94 -8.40 -7.60 -4.50 -6.97 -7.03 -7.47
6693 || orf19.6001 || SAP3 || || Secreted aspartyl proteinase, acts in utilization of protein as nitrogen source; assessment of virulence role complicated by URA3 effects; regulated by growth phase; produced by opaque phase cells; alpha-pheromone repressed || 1 -5.88 -5.84 -4.66 -5.46 -4.72 -5.09 -6.32 -6.11 -4.13 -5.64 -5.62 -5.58
6694 || orf19.6001 || SAP3 || || Secreted aspartyl proteinase, acts in utilization of protein as nitrogen source; assessment of virulence role complicated by URA3 effects; regulated by growth phase; produced by opaque phase cells; alpha-pheromone repressed || 1 -4.87 -4.21 -3.83 -4.55 -3.27 -4.30 -5.62 -5.19 -3.51 -4.43 -4.40 -4.24
6695 || orf19.7597 || PGA12 || || Putative GPI-anchored protein || 1 1.52 1.65 2.42 2.60 -3.90 -3.41 -2.85 -3.04 -2.40 -3.74 -4.80 -4.00 -2.06 -4.25 -4.44 -4.45
6696 || orf19.5716 || SAP4 || || Secreted aspartyl proteinase; sap4,5,6 mutant defective in protein utilization for nitrogen; virulence role complicated by URA3 effects; expressed during mucosal and systemic infections; N-glycosylated; rat catheter, Spider biofilm induced || 1 1.37 1.37 1.60 1.62 -5.64 -5.53 -3.31 -2.43 -3.64 -3.09 -6.07 -6.72 -2.26 -5.43 -5.92 -5.12
6697 || orf19.5542 || SAP6 || || Secreted aspartyl protease; expressed during hyphal growth, oral carriage, infection; sap4,5,6 triple mutant defective in protein utilization as N source; virulence role affecte by URA3; N-glycosylated; rat catheter biofilm induced || 1 1.46 1.12 1.34 1.20 -5.90 -5.60 -3.45 -2.68 -3.64 -3.02 -6.36 -5.86 -2.18 -4.51 -5.54 -3.34
6698 || orf19.5728 || || || Putative cytochrome P450; Spider biofilm induced || 1 1.98 1.98 2.03 2.71 -6.61 -4.11 -3.59 -4.49 -0.49 -8.24 -4.81 -1.29 -3.93 -7.44 -4.70
6699 || orf19.5307 || JEN2 || || Dicarboxylic acid transporter; regulated by glucose repression; induced by Rgt1; disruptants not obtained by UAU1 method; rat catheter and Spider biofilm induced || 1 1.12 1.01 1.81 2.09 -6.88 -9.62 -2.54 -3.28 -2.70 0.00 -6.20 -5.46 -2.58 -3.69 -5.69 -5.54
6700 || orf19.2460 || || || Protein of unknown function; substrate for Kex2 processing in vitro; repressed by alpha pheromone in SpiderM medium; Spider biofilm induced; Bcr1-repressed in a/a RPMI biofilms || 1 1.26 1.17 1.04 2.87 -7.14 -7.93 -2.15 -1.38 -2.84 0.11 -5.42 -5.41 -1.90 -2.87 -6.39 -5.77
6701 || orf19.6784 || PGA32 || || Putative GPI-anchored adhesin-like protein; induced in high iron; Spider biofilm induced || 1 1.07 0.94 1.18 1.87 -3.00 -4.19 -1.16 -0.36 -1.50 0.27 -2.15 -2.26 -1.19 -1.59 -2.47 -2.98
6702 || orf19.1655 || PXP2 || || Putative acyl-CoA oxidase; enzyme of fatty acid beta-oxidation; induced during macrophage infection; opaque specific transcript; putative peroxisome targeting signal; Spider biofilm induced || 1 1.82 1.81 2.03 1.74 -4.10 -6.09 -1.73 -0.93 -2.85 0.41 -4.49 -4.76 -0.20 -2.84 -5.50 -3.63
6703 || orf19.1655 || PXP2 || || Putative acyl-CoA oxidase; enzyme of fatty acid beta-oxidation; induced during macrophage infection; opaque specific transcript; putative peroxisome targeting signal; Spider biofilm induced || 1 1.61 1.58 2.18 1.69 -5.15 -5.82 -1.91 -1.24 -2.88 0.77 -4.73 -3.98 -0.43 -2.06 -5.21 -3.12
6704 || orf19.1655 || PXP2 || || Putative acyl-CoA oxidase; enzyme of fatty acid beta-oxidation; induced during macrophage infection; opaque specific transcript; putative peroxisome targeting signal; Spider biofilm induced || 1 1.43 1.37 1.66 1.66 -5.49 -6.07 -1.81 -1.22 -3.23 0.38 -4.83 -4.77 -0.56 -2.83 -5.77 -3.57
6705 || orf19.1655 || PXP2 || || Putative acyl-CoA oxidase; enzyme of fatty acid beta-oxidation; induced during macrophage infection; opaque specific transcript; putative peroxisome targeting signal; Spider biofilm induced || 1 1.46 1.43 2.12 1.78 -5.77 -5.55 -1.93 -1.17 -3.51 0.21 -4.90 -4.41 -0.46 -2.86 -5.80 -3.62
6706 || orf19.1655 || PXP2 || || Putative acyl-CoA oxidase; enzyme of fatty acid beta-oxidation; induced during macrophage infection; opaque specific transcript; putative peroxisome targeting signal; Spider biofilm induced || 1 1.55 1.69 2.27 1.99 -5.69 -5.01 -1.86 -1.02 -2.57 0.80 -4.39 -3.87 -0.45 -2.61 -5.32 -2.89
6707 || orf19.2253 || || || Protein of unknown function; expression regulated by white-opaque switch; repressed by alpha pheromone in SpiderM medium; Spider biofilm induced || 1 1.24 1.35 1.35 2.31 -3.50 -3.18 -0.78 -0.63 -1.54 0.19 -4.28 -4.18 -0.18 -0.99 -2.90 -3.05
6708 || orf19.532 || RBR2 || || Cell wall protein; expression repressed by Rim101; transcript regulated upon white-opaque switching; repressed by alpha pheromone in SpiderM medium; macrophage-induced gene || 1 0.97 0.75 1.33 2.19 -2.68 -3.27 -0.94 -0.38 -1.93 -0.07 -3.67 -3.32 -0.63 -0.78 -2.23 -3.08
6709 || orf19.532 || RBR2 || || Cell wall protein; expression repressed by Rim101; transcript regulated upon white-opaque switching; repressed by alpha pheromone in SpiderM medium; macrophage-induced gene || 1 0.62 0.52 1.07 2.12 -2.45 -3.51 -0.93 -0.41 -1.93 -0.29 -3.48 -3.53 -0.68 -0.63 -1.90 -3.52
6710 || orf19.532 || RBR2 || || Cell wall protein; expression repressed by Rim101; transcript regulated upon white-opaque switching; repressed by alpha pheromone in SpiderM medium; macrophage-induced gene || 1 0.78 0.50 0.85 1.76 -2.46 -3.37 -0.81 -0.46 -1.98 0.08 -3.55 -3.32 -0.74 -0.62 -1.99 -3.15
6711 || orf19.532 || RBR2 || || Cell wall protein; expression repressed by Rim101; transcript regulated upon white-opaque switching; repressed by alpha pheromone in SpiderM medium; macrophage-induced gene || 1 0.44 0.32 0.87 1.86 -2.68 -3.32 -1.03 -0.59 -2.00 -0.05 -3.43 -3.70 -0.83 -0.60 -2.10 -3.39
6712 || orf19.1239 || || || Secreted protein; exogenously expressed protein is a substrate for Kex2 processing in vitro; fluconazole-regulated; Spider biofilm induced || 1 0.75 0.63 1.10 1.92 -3.33 -5.96 -1.12 -0.96 -2.69 0.99 -3.99 -6.62 -0.75 -2.11 -3.87 -5.18
6713 || orf19.2460 || || || Protein of unknown function; substrate for Kex2 processing in vitro; repressed by alpha pheromone in SpiderM medium; Spider biofilm induced; Bcr1-repressed in a/a RPMI biofilms || 1 1.21 1.13 1.21 3.01 -3.84 -6.06 -1.57 -1.18 -2.52 0.20 -4.14 -7.03 -1.64 -2.50 -3.92 -6.74
6714 || orf19.2460 || || || Protein of unknown function; substrate for Kex2 processing in vitro; repressed by alpha pheromone in SpiderM medium; Spider biofilm induced; Bcr1-repressed in a/a RPMI biofilms || 1 1.74 1.66 1.42 3.02 -4.64 -6.13 -1.77 -0.99 -2.52 0.02 -5.83 -7.47 -1.65 -2.78 -5.15 -7.39
6715 || orf19.2460 || || || Protein of unknown function; substrate for Kex2 processing in vitro; repressed by alpha pheromone in SpiderM medium; Spider biofilm induced; Bcr1-repressed in a/a RPMI biofilms || 1 1.45 1.22 1.27 3.06 -5.99 -2.22 -1.43 -3.09 -0.10 -7.12 -8.43 -2.07 -3.01 -6.99 -10.03
6716 || orf19.5714 || SAP1 || || Secreted aspartyl proteinase; acts in utilization of protein as nitrogen source; assessment of virulence role complicated by URA3 effects; regulated by growth phase, alpha-pheromone; produced by opaque cells || 1 -7.12 -7.40 -2.65 -2.07 -2.46 -1.87 -7.99 -7.30 -1.30 -5.19 -7.39 -7.96
6717 || orf19.6678 || || || Protein of unknown function; Hap43-repressed gene || 1 1.12 1.36 2.18 2.46 -2.59 -2.47 -0.89 -1.09 -0.91 -1.41 -3.16 -2.86 -0.92 -1.50 -2.91 -3.05
6718 || orf19.6678 || || || Protein of unknown function; Hap43-repressed gene || 1 1.55 1.50 2.01 2.57 -2.56 -4.64 -1.24 -1.27 -1.17 -1.31 -3.91 -3.61 -1.45 -1.19 -3.73 -3.52
6719 || orf19.6518 || || || Predicted aldehyde dehydrogenase [NAD(P)+]; Spider biofilm induced || 1 0.88 1.11 1.75 1.93 -3.34 -3.85 -0.69 -0.92 -0.64 -0.06 -3.27 -2.67 -1.46 -1.41 -2.85 -2.78
6720 || orf19.6518 || || || Predicted aldehyde dehydrogenase [NAD(P)+]; Spider biofilm induced || 1 1.30 1.23 1.82 1.90 -2.73 -3.20 -0.71 -0.76 -0.48 0.12 -3.35 -3.38 -1.11 -1.67 -3.35 -2.87
6721 || orf19.1541 || || || Protein with a globin-like domain; repressed by alpha pheromone in SpiderM medium; Spider biofilm induced || 1 2.09 2.11 2.10 3.11 -5.12 -6.03 -1.84 -1.64 -2.67 -0.02 -6.18 -6.56 -1.20 -2.22 -6.14 -6.05
6722 || orf19.356 || GTT13 || || Putative glutathione S-transferase; opaque-specific transcript; repressed by alpha pheromone in SpiderM medium; Spider biofilm induced || 1 1.73 1.83 2.09 2.78 -3.72 -5.06 -1.81 -1.90 -2.34 -0.41 -4.92 -5.08 -0.64 -2.39 -3.91 -4.93
6723 || orf19.1541 || || || Protein with a globin-like domain; repressed by alpha pheromone in SpiderM medium; Spider biofilm induced || 1 2.50 2.61 2.24 3.43 -4.32 -5.92 -1.63 -1.35 -2.96 -0.44 -4.67 -5.63 -1.28 -2.33 -3.87 -4.90
6724 || orf19.1541 || || || Protein with a globin-like domain; repressed by alpha pheromone in SpiderM medium; Spider biofilm induced || 1 2.17 2.31 1.86 2.95 -4.08 -6.17 -2.02 -1.78 -3.02 -0.47 -4.18 -6.37 -1.26 -2.58 -4.58 -6.00
6725 || orf19.1541 || || || Protein with a globin-like domain; repressed by alpha pheromone in SpiderM medium; Spider biofilm induced || 1 2.30 2.30 2.07 3.09 -4.07 -6.07 -1.83 -1.47 -2.38 -0.23 -4.13 -4.08 -1.21 -2.35 -4.81 -4.32
6726 || orf19.2253 || || || Protein of unknown function; expression regulated by white-opaque switch; repressed by alpha pheromone in SpiderM medium; Spider biofilm induced || 1 1.13 1.17 1.31 2.35 -3.42 -3.80 -0.92 -0.88 -1.77 -0.33 -3.08 -2.95 -0.77 -1.91 -2.17 -3.18
6727 || orf19.5307 || JEN2 || || Dicarboxylic acid transporter; regulated by glucose repression; induced by Rgt1; disruptants not obtained by UAU1 method; rat catheter and Spider biofilm induced || 1 1.79 1.46 2.40 2.32 -3.88 -3.93 -1.69 -1.95 -1.87 0.42 -3.87 -4.20 -1.67 -2.79 -3.36 -4.56
6728 || orf19.5760 || IHD1 || || GPI-anchored protein; alkaline, hypha-induced; regulated by Nrg1, Rfg1, Tup1 and Tsa1, Tsa1B in minimal media at 37; oralpharyngeal candidasis induced ; Spider biofilm induced; regulated in Spider biofilms by Tec1, Efg1, Ndt80, Rob1, Brg1 || 1 0.52 0.44 1.25 1.44 -1.56 -2.40 -0.48 -0.35 -0.61 0.09 -1.66 -2.97 -0.91 -1.12 -2.37 -2.20
6729 || orf19.852 || SAP98 || || Glycosyl-phosphatidylinositol-anchored aspartic endopeptidase; regulated by Gcn2p and Gcn4p; expressed only in opaque MTLa/MTLa cells || 1 2.34 2.29 2.68 3.09 -4.31 -3.86 -1.94 -1.77 -1.60 -1.08 -4.50 -4.20 -2.79 -4.07 -4.08 -3.87
6730 || orf19.852 || SAP98 || || Glycosyl-phosphatidylinositol-anchored aspartic endopeptidase; regulated by Gcn2p and Gcn4p; expressed only in opaque MTLa/MTLa cells || 1 1.77 1.62 2.62 3.07 -4.39 -3.93 -2.60 -2.51 -1.96 -1.27 -4.40 -4.32 -3.07 -4.51 -4.32 -3.89
6731 || orf19.6329 || || || Protein of unknown function; opaque-specific transcript; fluconazole-repressed; induced in cyr1 mutant and in oralpharyngeal candidasis; Spider biofilm induced || 1 1.05 1.03 1.43 2.39 -2.52 -3.32 -1.74 -1.41 -2.09 -0.64 -2.20 -2.43 -1.59 -2.99 -2.31 -2.64
6732 || orf19.6329 || || || Protein of unknown function; opaque-specific transcript; fluconazole-repressed; induced in cyr1 mutant and in oralpharyngeal candidasis; Spider biofilm induced || 1 1.01 0.93 1.58 2.49 -2.67 -2.90 -1.74 -1.22 -1.83 -0.02 -1.89 -1.92 -1.40 -2.06 -2.04 -2.29
6733 || orf19.893 || PGA17 || || Putative GPI-anchored protein; exogenously expressed protein substrate for Kex2 processing in vitro; repressed by alpha pheromone in SpiderM medium; macrophage-induced; induced in oralpharyngeal candidiasis; Spider biofilm induced || 1 1.21 1.27 1.50 2.45 -7.18 -6.68 -3.51 -2.91 -4.53 -0.64 -5.55 -5.53 -2.87 -3.69 -5.62 -6.85
6734 || orf19.893 || PGA17 || || Putative GPI-anchored protein; exogenously expressed protein substrate for Kex2 processing in vitro; repressed by alpha pheromone in SpiderM medium; macrophage-induced; induced in oralpharyngeal candidiasis; Spider biofilm induced || 1 1.41 1.29 1.88 2.84 -6.95 -7.22 -3.51 -2.85 -4.59 -0.65 -5.72 -6.55 -2.81 -3.90 -5.85 -6.61
6735 || orf19.5728 || || || Putative cytochrome P450; Spider biofilm induced || 1 1.70 1.79 1.97 2.59 -4.07 -7.16 -3.87 -3.33 -4.70 -0.83 -5.10 -4.66 -1.42 -3.94 -4.86 -5.22
6736 || orf19.5728 || || || Putative cytochrome P450; Spider biofilm induced || 1 2.05 2.00 2.26 2.98 -3.31 -5.46 -2.46 -2.16 -3.76 -0.43 -3.26 -4.35 -1.14 -3.58 -3.36 -4.70
6737 || orf19.2787 || PRY1 || || Pry family pathogenesis-related protein; extracellular; opaque specific transcript; repressed by alpha pheromone in SpiderM medium; possibly essential, disruptants not obtained by UAU1 method; Spider biofilm induced || 1 1.02 0.89 1.76 2.52 -2.05 -4.43 -1.82 -1.71 -2.84 -0.99 -2.88 -3.10 -1.27 -3.49 -2.46 -3.66
6738 || orf19.1370 || || || Protein of unknown function; expression regulated by white-opaque switch; repressed by alpha pheromone in SpiderM medium || 1 1.96 1.81 2.43 3.54 -3.60 -5.82 -2.62 -2.85 -5.18 -2.59 -4.34 -6.35 -2.88 -5.08 -3.44 -5.84
6739 || orf19.1370 || || || Protein of unknown function; expression regulated by white-opaque switch; repressed by alpha pheromone in SpiderM medium || 1 1.65 1.37 2.16 3.31 -3.98 -4.63 -3.37 -3.13 -4.66 -2.28 -3.71 -5.92 -3.37 -4.78 -4.43 -5.38
6740 || orf19.7094 || HGT12 || || Glucose, fructose, mannose transporter; major facilitator superfamily; role in macrophage-induced hyphal growth; detected at germ tube plasma membrane by mass spectrometry; Snf3p-induced; 12 probable transmembrane segments || 1 1.34 1.29 1.83 2.67 -4.46 -6.58 -3.80 -4.18 -5.46 -0.53 -5.36 -6.45 -4.56 -5.17 -4.67 -6.17
6741 || orf19.893 || PGA17 || || Putative GPI-anchored protein; exogenously expressed protein substrate for Kex2 processing in vitro; repressed by alpha pheromone in SpiderM medium; macrophage-induced; induced in oralpharyngeal candidiasis; Spider biofilm induced || 1 1.26 1.10 1.48 2.41 -4.51 -5.45 -3.30 -2.81 -3.00 -1.00 -4.70 -5.21 -2.85 -4.00 -4.22 -4.55
6742 || orf19.893 || PGA17 || || Putative GPI-anchored protein; exogenously expressed protein substrate for Kex2 processing in vitro; repressed by alpha pheromone in SpiderM medium; macrophage-induced; induced in oralpharyngeal candidiasis; Spider biofilm induced || 1 1.42 1.31 1.73 2.80 -4.97 -6.82 -3.62 -2.68 -5.19 -0.92 -5.23 -6.56 -2.57 -3.86 -4.86 -6.15
6743 || orf19.4934 || OP4 || || Ala- Leu- and Ser-rich protein; secreted; N-terminal hydrophobic region; possible glycosylation; opaque-specific transcript; repressed by alpha pheromone in opaque MTLa homozygotes; fluconazole-induced; Spider biofilm induced || 1 -6.29 -7.82 -4.55 -4.07 -4.93 -2.31 -7.19 -8.34 -2.78 -5.07 -6.42 -8.36
6744 || orf19.4934 || OP4 || || Ala- Leu- and Ser-rich protein; secreted; N-terminal hydrophobic region; possible glycosylation; opaque-specific transcript; repressed by alpha pheromone in opaque MTLa homozygotes; fluconazole-induced; Spider biofilm induced || 1 -5.45 -7.60 -4.89 -4.37 -4.74 -1.97 -6.80 -8.35 -2.74 -4.48 -6.26 -7.68
6745 || orf19.1370 || || || Protein of unknown function; expression regulated by white-opaque switch; repressed by alpha pheromone in SpiderM medium || 1 1.87 1.75 2.40 -5.50 -7.62 -5.26 -4.18 -6.19 -2.40 -7.23 -9.19 -3.47 -4.75 -6.75 -8.11
6746 || orf19.1370 || || || Protein of unknown function; expression regulated by white-opaque switch; repressed by alpha pheromone in SpiderM medium || 1 2.11 2.02 2.60 3.58 -4.77 -6.40 -4.06 -3.61 -5.65 -2.34 -6.21 -7.37 -2.83 -4.64 -4.79 -7.33
6747 || orf19.2941 || SCW4 || || Putative cell wall protein; substrate for Kex2p processing in vitro; expression regulated by white-opaque switch; alkaline repressed; possibly essential (UAU1 method); flow model biofilm induced; Spider biofilm induced || 1 1.22 1.37 1.54 2.72 -3.25 -4.56 -2.50 -2.49 -4.42 -0.77 -5.38 -5.44 -2.14 -3.70 -3.45 -5.30
6748 || orf19.2941 || SCW4 || || Putative cell wall protein; substrate for Kex2p processing in vitro; expression regulated by white-opaque switch; alkaline repressed; possibly essential (UAU1 method); flow model biofilm induced; Spider biofilm induced || 1 1.57 1.62 1.98 3.04 -3.61 -7.23 -2.57 -2.57 -4.57 -0.77 -5.27 -6.90 -2.27 -3.87 -4.40 -6.66
6749 || orf19.1541 || || || Protein with a globin-like domain; repressed by alpha pheromone in SpiderM medium; Spider biofilm induced || 1 1.44 1.48 1.64 2.70 -2.11 -3.58 -1.96 -1.99 -2.81 -0.62 -3.50 -5.20 -0.93 -2.21 -3.43 -4.65
6750 || orf19.2787 || PRY1 || || Pry family pathogenesis-related protein; extracellular; opaque specific transcript; repressed by alpha pheromone in SpiderM medium; possibly essential, disruptants not obtained by UAU1 method; Spider biofilm induced || 1 1.26 1.17 1.44 2.79 -2.45 -3.82 -1.56 -1.60 -2.40 -0.55 -2.53 -4.43 -1.94 -2.64 -2.51 -4.35
6751 || orf19.2787 || PRY1 || || Pry family pathogenesis-related protein; extracellular; opaque specific transcript; repressed by alpha pheromone in SpiderM medium; possibly essential, disruptants not obtained by UAU1 method; Spider biofilm induced || 1 1.27 1.33 1.72 2.72 -3.02 -3.37 -1.63 -1.86 -2.67 -0.64 -3.62 -5.04 -2.18 -2.97 -3.09 -3.80
6752 || orf19.5728 || || || Putative cytochrome P450; Spider biofilm induced || 1 1.84 1.75 2.23 2.97 -3.35 -3.77 -2.92 -3.00 -3.30 -0.38 -4.05 -5.56 -1.48 -3.19 -3.69 -4.00
6753 || orf19.893 || PGA17 || || Putative GPI-anchored protein; exogenously expressed protein substrate for Kex2 processing in vitro; repressed by alpha pheromone in SpiderM medium; macrophage-induced; induced in oralpharyngeal candidiasis; Spider biofilm induced || 1 1.63 1.62 1.87 2.84 -1.40 -3.89 -1.39 -1.95 -3.50 -0.80 -3.17 -4.16 -1.60 -3.36 -1.81 -4.05
6754 || orf19.7094 || HGT12 || || Glucose, fructose, mannose transporter; major facilitator superfamily; role in macrophage-induced hyphal growth; detected at germ tube plasma membrane by mass spectrometry; Snf3p-induced; 12 probable transmembrane segments || 1 1.03 0.94 2.08 2.82 -1.99 -4.24 -2.23 -2.74 -4.52 -0.16 -2.94 -4.27 -1.81 -3.48 -2.37 -3.94
6755 || orf19.7094 || HGT12 || || Glucose, fructose, mannose transporter; major facilitator superfamily; role in macrophage-induced hyphal growth; detected at germ tube plasma membrane by mass spectrometry; Snf3p-induced; 12 probable transmembrane segments || 1 0.61 0.58 1.67 2.37 -2.12 -4.05 -1.45 -1.88 -2.96 -0.38 -2.32 -4.19 -1.87 -3.80 -1.86 -3.72
6756 || orf19.356 || GTT13 || || Putative glutathione S-transferase; opaque-specific transcript; repressed by alpha pheromone in SpiderM medium; Spider biofilm induced || 1 1.74 1.78 2.38 3.10 -2.19 -3.74 -1.21 -1.12 -2.16 -0.28 -2.75 -3.77 -0.16 -2.45 -2.15 -3.82
6757 || orf19.356 || GTT13 || || Putative glutathione S-transferase; opaque-specific transcript; repressed by alpha pheromone in SpiderM medium; Spider biofilm induced || 1 2.01 2.01 2.63 3.37 -2.89 -3.85 -1.80 -1.30 -2.05 -0.50 -3.27 -4.80 -0.57 -3.38 -2.91 -5.93
6758 || orf19.5307 || JEN2 || || Dicarboxylic acid transporter; regulated by glucose repression; induced by Rgt1; disruptants not obtained by UAU1 method; rat catheter and Spider biofilm induced || 1 1.61 1.58 2.01 2.41 -1.52 -2.67 -1.38 -1.96 -1.21 0.44 -3.36 -4.05 -0.78 -2.63 -2.83 -4.01
6759 || orf19.5303 || PGA30 || || GPI-anchored protein of cell wall || 1 1.90 1.84 2.57 2.98 -2.69 -3.93 -1.37 -1.72 -0.29 -0.90 -4.59 -4.32 -2.47 -3.97 -4.16 -4.45
6760 || orf19.5303 || PGA30 || || GPI-anchored protein of cell wall || 1 1.74 1.66 2.50 2.60 -4.83 -5.33 -1.59 -1.79 -0.63 -0.91 -6.56 -6.22 -4.06 -5.17 -5.43 -6.75
6761 || orf19.5303 || PGA30 || || GPI-anchored protein of cell wall || 1 2.00 1.82 2.62 2.87 -6.23 -7.78 -1.45 -1.71 -0.36 -0.99 -6.63 -6.86 -3.87 -5.52 -6.85 -6.92
6762 || orf19.3926 || RNY11 || || Ortholog(s) have endoribonuclease activity, role in RNA catabolic process, apoptotic process, cell morphogenesis and cytosol, extracellular region, vacuole localization || 1 1.80 1.66 2.06 2.73 -3.95 -3.75 -3.36 -3.46 -2.71 -1.93 -7.49 -7.95 -5.27 -4.88 -6.80 -8.51
6763 || orf19.3926 || RNY11 || || Ortholog(s) have endoribonuclease activity, role in RNA catabolic process, apoptotic process, cell morphogenesis and cytosol, extracellular region, vacuole localization || 1 1.85 1.73 2.02 2.75 -3.97 -3.60 -3.30 -3.58 -2.67 -1.82 -7.41 -7.30 -5.13 -4.49 -6.88 -7.51
6764 || orf19.3926 || RNY11 || || Ortholog(s) have endoribonuclease activity, role in RNA catabolic process, apoptotic process, cell morphogenesis and cytosol, extracellular region, vacuole localization || 1 1.92 1.82 2.36 3.19 -3.94 -3.76 -3.34 -3.14 -2.85 -1.86 -7.63 -7.01 -4.88 -4.96 -6.93 -7.51
6765 || orf19.3926 || RNY11 || || Ortholog(s) have endoribonuclease activity, role in RNA catabolic process, apoptotic process, cell morphogenesis and cytosol, extracellular region, vacuole localization || 1 2.64 2.53 2.53 3.36 -3.13 -3.31 -2.71 -2.55 -2.04 -1.58 -6.24 -5.10 -4.40 -4.62 -6.29 -7.45
6766 || orf19.1308 || || || Predicted membrane transporter, member of the drug:proton antiporter (14 spanner) (DHA2) family, major facilitator superfamily (MFS) || 1 0.52 0.50 0.82 1.11 -0.89 -0.99 -0.87 -0.44 -0.74 0.22 -1.08 -0.80 -0.37 -0.05 -1.00 -1.07
6767 || orf19.6066 || || || Hexadecenal dehydrogenase; involved in the conversion of sphingosine 1-phosphate breakdown product hexadecenal to hexadecenoic acid; Spider biofilm induced || 1 1.00 0.92 1.40 1.69 -1.18 -1.00 -0.89 -0.94 -0.98 -0.07 -2.20 -1.58 -0.87 -0.31 -0.80 -1.90
6768 || orf19.6066 || || || Hexadecenal dehydrogenase; involved in the conversion of sphingosine 1-phosphate breakdown product hexadecenal to hexadecenoic acid; Spider biofilm induced || 1 0.97 0.98 1.42 1.84 -1.23 -0.97 -0.97 -0.93 -0.90 -0.07 -2.24 -1.42 -0.73 -0.70 -0.69 -1.71
6769 || orf19.6167 || AYR1 || || Putative oxidoreductase; transcriptionally induced by interaction with macrophage; rat catheter biofilm repressed || 1 1.04 0.82 1.01 1.30 -0.88 -0.77 -0.88 -0.31 -0.39 0.01 -1.18 -1.00 -0.77 -0.60 -1.12 -1.38
6770 || orf19.6445 || ECI1 || || Protein similar to S. cerevisiae Eci1p, which is involved in fatty acid oxidation; transposon mutation affects filamentous growth; expression is regulated upon white-opaque switching || 1 1.08 1.12 1.63 1.88 -1.12 -1.13 -1.02 -0.74 -1.01 0.17 -2.01 -1.45 -0.88 -0.99 -2.15 -1.89
6771 || orf19.6445 || ECI1 || || Protein similar to S. cerevisiae Eci1p, which is involved in fatty acid oxidation; transposon mutation affects filamentous growth; expression is regulated upon white-opaque switching || 1 1.03 0.98 1.55 1.62 -1.15 -1.31 -1.25 -0.94 -1.40 -0.10 -2.40 -1.70 -1.14 -0.77 -2.12 -1.81
6772 || orf19.6830 || || || Putative enoyl-CoA hydratase; Spider biofilm induced || 1 1.03 0.94 1.42 1.92 -1.59 -1.42 -1.07 -0.97 -1.27 -0.22 -2.30 -1.85 -1.82 -0.88 -1.53 -2.18
6773 || orf19.6830 || || || Putative enoyl-CoA hydratase; Spider biofilm induced || 1 1.30 1.15 1.71 2.16 -1.53 -1.66 -1.14 -0.75 -1.19 -0.33 -2.38 -1.85 -1.65 -1.11 -1.52 -2.23
6774 || orf19.1704 || FOX3 || || Putative peroxisomal 3-oxoacyl CoA thiolase; transcript regulated by white-opaque switch; Spider biofilm induced || 1 0.90 0.93 1.25 1.72 -1.07 -1.43 -0.89 -0.67 -0.99 -0.08 -1.73 -1.19 -1.01 -0.71 -1.29 -1.47
6775 || orf19.1704 || FOX3 || || Putative peroxisomal 3-oxoacyl CoA thiolase; transcript regulated by white-opaque switch; Spider biofilm induced || 1 0.96 1.02 1.40 1.74 -1.07 -1.15 -0.96 -0.74 -0.90 -0.15 -1.72 -1.00 -1.15 -0.76 -1.19 -1.44
6776 || orf19.1704 || FOX3 || || Putative peroxisomal 3-oxoacyl CoA thiolase; transcript regulated by white-opaque switch; Spider biofilm induced || 1 0.78 0.67 1.21 1.54 -1.49 -1.86 -1.34 -0.92 -1.46 -0.21 -2.55 -1.60 -1.47 -0.87 -1.61 -2.13
6777 || orf19.6830 || || || Putative enoyl-CoA hydratase; Spider biofilm induced || 1 1.13 1.09 1.53 1.97 -2.05 -2.14 -1.67 -1.24 -1.37 -0.43 -3.11 -2.00 -1.94 -1.37 -1.90 -2.08
6778 || orf19.7513 || ALK2 || || N-Alkane inducible cytochrome P450 || 1 1.99 2.01 2.39 2.59 -2.94 -3.44 -2.47 -1.81 -2.48 -0.32 -4.19 -3.76 -3.04 -1.98 -3.50 -3.46
6779 || orf19.7513 || ALK2 || || N-Alkane inducible cytochrome P450 || 1 1.49 1.57 1.95 2.35 -3.29 -3.87 -2.54 -2.08 -2.81 -0.24 -4.45 -3.14 -3.26 -2.18 -3.38 -3.47
6780 || orf19.6167 || AYR1 || || Putative oxidoreductase; transcriptionally induced by interaction with macrophage; rat catheter biofilm repressed || 1 0.73 0.68 0.92 1.01 -1.08 -0.84 -0.95 -0.54 -0.57 -0.01 -1.52 -1.06 -1.12 -0.66 -1.28 -1.34
6781 || orf19.6143 || || || Predicted long-chain-alcohol oxidase; Spider biofilm induced || 1 1.85 1.93 2.34 2.10 -2.13 -1.72 -1.96 -0.82 -1.16 0.53 -4.04 -2.73 -1.99 -1.34 -2.78 -3.25
6782 || orf19.6143 || || || Predicted long-chain-alcohol oxidase; Spider biofilm induced || 1 1.78 1.89 2.07 1.85 -2.23 -2.12 -2.18 -0.84 -1.27 0.40 -4.40 -3.18 -1.93 -1.68 -3.09 -4.03
6783 || orf19.1704 || FOX3 || || Putative peroxisomal 3-oxoacyl CoA thiolase; transcript regulated by white-opaque switch; Spider biofilm induced || 1 0.57 0.71 0.16 1.58 -1.12 -1.50 -1.25 -0.99 -1.46 -0.18 -2.23 -1.72 -1.17 -0.81 -1.55 -2.19
6784 || orf19.3926 || RNY11 || || Ortholog(s) have endoribonuclease activity, role in RNA catabolic process, apoptotic process, cell morphogenesis and cytosol, extracellular region, vacuole localization || 1 1.57 1.44 2.45 -1.05 -1.96 -1.37 -1.86 -1.54 -1.35 -2.38 -3.37 -1.25 -2.88 -1.78 -2.97
6785 || orf19.7512 || || || Has domain(s) with predicted electron carrier activity, heme binding, iron ion binding, oxidoreductase activity, acting on paired donors and with incorporation or reduction of molecular oxygen, more || 1 2.28 2.28 2.65 3.33 -1.59 -2.96 -2.34 -1.80 -2.91 -0.55 -3.14 -4.34 -2.49 -3.63 -2.06 -3.36
6786 || orf19.7512 || || || Has domain(s) with predicted electron carrier activity, heme binding, iron ion binding, oxidoreductase activity, acting on paired donors and with incorporation or reduction of molecular oxygen, more || 1 2.37 2.39 2.81 3.43 -1.29 -2.54 -3.12 -1.91 -3.95 -0.94 -3.78 -4.12 -2.24 -4.23 -2.49 -4.31
6787 || orf19.1224 || FRP3 || || Putative ammonium transporter; upregulated in the presence of human neutrophils; fluconazole-downregulated; repressed by nitric oxide; Spider biofilm induced; rat catheter biofilm repressed || 1 1.18 0.91 2.10 2.08 -0.51 -0.62 -3.08 -2.01 -2.35 -0.24 -2.95 -1.69 -1.72 -2.17 -1.53 -2.01
6788 || orf19.7520 || POT1 || || Putative peroxisomal 3-oxoacyl CoA thiolase; transcript regulated by Nrg1 and Mig1; farnesol regulated; Hap43-repressed || 1 0.37 0.41 0.94 1.42 -0.28 -0.89 -1.02 -1.00 -1.48 -0.72 -1.96 -1.60 -1.47 -1.54 -0.64 -1.52
6789 || orf19.7520 || POT1 || || Putative peroxisomal 3-oxoacyl CoA thiolase; transcript regulated by Nrg1 and Mig1; farnesol regulated; Hap43-repressed || 1 0.53 0.43 0.93 1.50 -0.26 -0.55 -0.93 -0.87 -1.39 -0.49 -1.98 -1.35 -1.13 -1.06 -0.62 -1.45
6790 || orf19.7520 || POT1 || || Putative peroxisomal 3-oxoacyl CoA thiolase; transcript regulated by Nrg1 and Mig1; farnesol regulated; Hap43-repressed || 1 0.43 0.47 1.05 1.50 -0.44 -0.49 -0.97 -0.83 -1.17 -0.31 -2.21 -1.09 -1.42 -0.94 -0.69 -1.26
6791 || orf19.1288 || FOX2 || || 3-hydroxyacyl-CoA epimerase; fatty acid beta-oxidation; induced by phagocytosis; regulated by Mig1, by white-opaque switch, by DNA methylation; transcriptional activation by oleate requires Ctf1; rat catheter and Spider biofilm induced || 1 0.83 0.83 1.68 2.18 -0.45 -0.77 -1.51 -1.22 -1.75 -0.28 -2.76 -1.67 -1.41 -1.32 -1.45 -3.03
6792 || orf19.1288 || FOX2 || || 3-hydroxyacyl-CoA epimerase; fatty acid beta-oxidation; induced by phagocytosis; regulated by Mig1, by white-opaque switch, by DNA methylation; transcriptional activation by oleate requires Ctf1; rat catheter and Spider biofilm induced || 1 0.98 0.93 1.71 2.00 -0.29 -0.55 -1.46 -1.19 -1.49 -0.19 -2.75 -1.45 -1.16 -1.40 -1.55 -2.32
6793 || orf19.6681 || || || Protein of unknown function; Spider biofilm induced || 1 0.69 0.50 0.99 1.20 -0.34 -0.16 -0.76 -0.61 -0.91 -0.18 -1.39 -1.34 -0.67 -0.49 -0.61 -1.18
6794 || orf19.7520 || POT1 || || Putative peroxisomal 3-oxoacyl CoA thiolase; transcript regulated by Nrg1 and Mig1; farnesol regulated; Hap43-repressed || 1 0.17 0.36 1.16 1.56 -0.16 -0.32 -0.62 -0.55 -0.81 -0.12 -1.54 -1.03 -1.01 -0.69 -0.50 -1.27
6795 || orf19.2787 || PRY1 || || Pry family pathogenesis-related protein; extracellular; opaque specific transcript; repressed by alpha pheromone in SpiderM medium; possibly essential, disruptants not obtained by UAU1 method; Spider biofilm induced || 1 0.95 0.87 0.46 1.48 -2.20 -1.26 -0.91 -1.07 -0.69 -0.49 -2.72 -2.16 0.42 -1.88 -2.56 -2.35
6796 || orf19.5455 || || || Ortholog(s) have mRNA binding, small GTPase regulator activity || 1 0.86 0.82 1.18 1.26 -1.63 -0.14 -0.77 -0.65 -0.23 -0.37 -1.93 -0.76 -0.07 -0.08 -1.58 -1.59
6797 || orf19.5455 || || || Ortholog(s) have mRNA binding, small GTPase regulator activity || 1 0.88 0.62 1.31 1.60 -1.58 0.05 -0.95 -0.78 -0.03 -0.32 -1.92 -1.10 0.09 -0.01 -1.44 -1.52
6798 || orf19.4826 || IDH1 || || Putative mitochondrial NAD-isocitrate dehydrogenase subunit 1; soluble protein in hyphae; protein level decrease in stationary phase cultures || 1 0.42 0.26 0.75 1.05 -0.29 -0.53 -0.16 -0.10 -0.32 -0.34 -1.15 -1.59 -0.05 -0.19 -0.80 -1.03
6799 || orf19.6709 || || || Predicted alpha/beta hydrolase; Spider biofilm induced || 1 0.78 0.82 1.81 1.94 -0.95 -0.62 -1.08 -0.97 -0.44 -0.63 -2.09 -1.72 -0.24 -0.41 -1.07 -1.61
6800 || orf19.6709 || || || Predicted alpha/beta hydrolase; Spider biofilm induced || 1 0.47 0.80 1.45 1.64 -1.28 -1.02 -1.64 -1.58 -0.75 -0.72 -3.55 -1.98 -0.29 -0.61 -1.29 -2.63
6801 || orf19.6782 || BMT1 || || Beta-mannosyltransferase, required for addition of the 1st beta-mannose residue to acid-stable fraction of cell wall phosphopeptidomannan; 9-gene family member; mutants induce higher levels of inflammatory cytokines in mouse dendritic cells || 1 0.98 0.87 0.64 0.78 -0.76 -0.41 -0.14 -0.34 -0.35 0.52 -1.85 -1.46 0.18 -0.23 -0.60 -2.11
6802 || orf19.6021 || IHD2 || || Protein of unknown function; induced during hyphae development; induced in low iron; Spider biofilm induced || 1 0.44 0.59 0.72 0.88 -0.45 -0.61 -0.20 -0.51 0.14 -0.08 -1.56 -1.38 0.34 -0.35 -0.32 -1.85
6803 || orf19.3418 || || || Ortholog(s) have endoplasmic reticulum, fungal-type vacuole localization || 1 0.43 0.34 1.18 1.46 -0.50 -0.42 -0.08 -0.60 0.03 -0.11 -1.94 -1.25 -0.25 0.05 -1.08 -1.53
6804 || orf19.7434 || GLG2 || || Putative self-glucosylating initiator of glycogen synthesis; expression regulated upon white-opaque switch; hypha-induced; Spider biofilm induced || 1 0.79 0.81 1.67 2.01 -1.48 -0.98 -0.56 -0.56 -0.30 0.27 -2.91 -2.88 0.11 -0.17 -1.03 -2.68
6805 || orf19.7434 || GLG2 || || Putative self-glucosylating initiator of glycogen synthesis; expression regulated upon white-opaque switch; hypha-induced; Spider biofilm induced || 1 0.86 0.90 1.57 1.74 -0.74 -0.38 -0.62 -0.50 -0.31 0.15 -2.18 -2.02 0.24 -0.04 -0.80 -1.97
6806 || orf19.7434 || GLG2 || || Putative self-glucosylating initiator of glycogen synthesis; expression regulated upon white-opaque switch; hypha-induced; Spider biofilm induced || 1 1.37 1.44 2.04 2.30 -1.19 -0.68 -0.60 -0.07 -0.61 0.34 -4.10 -2.53 0.19 0.12 -0.95 -2.94
6807 || orf19.7434 || GLG2 || || Putative self-glucosylating initiator of glycogen synthesis; expression regulated upon white-opaque switch; hypha-induced; Spider biofilm induced || 1 0.93 0.78 1.51 1.76 -0.46 -0.13 -0.47 -0.33 -0.15 0.31 -1.48 -1.37 0.04 0.25 -0.59 -1.62
6808 || orf19.3358 || LSC1 || || Putative succinate-CoA ligase subunit; induced by high iron; fluconazole-induced; protein present in exponential and stationary growth phase yeast cultures; Spider biofilm repressed || 1 0.56 0.56 1.08 1.12 -0.74 -0.28 -0.44 -0.30 -0.35 -0.18 -1.64 -1.33 -0.45 0.06 -1.83 -0.87
6809 || orf19.3358 || LSC1 || || Putative succinate-CoA ligase subunit; induced by high iron; fluconazole-induced; protein present in exponential and stationary growth phase yeast cultures; Spider biofilm repressed || 1 0.66 0.52 -0.92 -0.57 -0.56 -0.46 -0.39 -0.25 -1.82 -1.65 -0.47 -0.14 -2.06 -1.41
6810 || orf19.4381 || VTC3 || || Putative polyphosphate synthetase; downregulated in core caspofungin response; Hog1p-induced; transcription is opaque-specific; fungal-specific (no human or murine homolog) || 1 0.72 0.63 0.70 0.79 -1.65 -0.98 -0.38 -0.35 -0.28 -0.04 -2.38 -1.50 -0.29 -0.12 -2.35 -2.10
6811 || orf19.1774 || || || Predicted dehydrogenase; transcript upregulated in an RHE model of oral candidiasis; virulence-group-correlated expression; Spider biofilm repressed || 1 0.84 0.82 1.77 1.96 -2.24 -1.96 -0.12 -0.38 -0.80 -1.09 -3.67 -3.53 -0.88 -0.59 -3.60 -3.53
6812 || orf19.1117 || || || Protein similar to Candida boidinii formate dehydrogenase; virulence-group-correlated expression; Hap43-repressed; Spider biofilm repressed || 1 0.81 0.86 1.86 1.52 -2.21 -1.89 -0.29 -0.62 -0.91 -1.44 -4.51 -3.67 -0.81 -1.03 -3.77 -3.76
6813 || orf19.1117 || || || Protein similar to Candida boidinii formate dehydrogenase; virulence-group-correlated expression; Hap43-repressed; Spider biofilm repressed || 1 1.13 1.21 2.06 1.62 -2.06 -1.72 -0.24 -0.55 -0.57 -1.23 -4.31 -3.80 -0.71 -1.45 -3.14 -4.28
6814 || orf19.1774 || || || Predicted dehydrogenase; transcript upregulated in an RHE model of oral candidiasis; virulence-group-correlated expression; Spider biofilm repressed || 1 1.52 1.50 2.16 -1.87 -1.43 -0.11 -0.39 -0.28 -1.03 -4.28 -3.76 -0.40 -1.57 -2.90 -4.43
6815 || orf19.638 || FDH1 || || Formate dehydrogenase; oxidizes formate to CO2; Mig1 regulated; induced by macrophages; fluconazole-repressed; repressed by Efg1 in yeast, not hyphal conditions; stationary phase enriched; rat catheter and Spider biofilm induced || 1 1.62 1.51 2.71 2.34 -1.89 -1.35 -0.15 -0.31 -0.26 -0.84 -4.37 -3.92 -0.53 -1.82 -3.01 -4.35
6816 || orf19.638 || FDH1 || || Formate dehydrogenase; oxidizes formate to CO2; Mig1 regulated; induced by macrophages; fluconazole-repressed; repressed by Efg1 in yeast, not hyphal conditions; stationary phase enriched; rat catheter and Spider biofilm induced || 1 1.40 1.45 2.13 -2.08 -1.10 -0.28 -0.49 -0.04 -0.76 -4.45 -3.09 -0.54 -1.80 -2.62 -3.76
6817 || orf19.1774 || || || Predicted dehydrogenase; transcript upregulated in an RHE model of oral candidiasis; virulence-group-correlated expression; Spider biofilm repressed || 1 1.42 -2.05 -1.20 -0.15 -0.50 -0.11 -0.81 -4.54 -3.28 -0.65 -1.26 -2.76 -3.92
6818 || orf19.1117 || || || Protein similar to Candida boidinii formate dehydrogenase; virulence-group-correlated expression; Hap43-repressed; Spider biofilm repressed || 1 -0.19 1.32 -1.93 -1.12 -0.16 -0.47 -0.08 -0.82 -4.46 -3.22 -0.44 -1.23 -2.94 -3.87
6819 || orf19.3444 || || || Predicted membrane transporter, member of the drug:proton antiporter (14 spanner) (DHA2) family, major facilitator superfamily (MFS); Hap43p-repressed gene || 1 0.58 0.97 1.85 1.49 -1.59 -1.56 -0.21 -0.20 0.49 -0.03 -4.08 -2.19 -0.43 -0.29 -2.83 -2.67
6820 || orf19.1709 || || || Sterol carrier domain protein; alkaline downregulated; colony morphology-related gene regulation by Ssn6; Spider biofilm induced || 1 2.05 2.08 2.46 2.68 -2.06 -2.24 -0.37 -0.34 -0.18 0.40 -3.18 -2.44 -0.23 -0.70 -2.51 -3.08
6821 || orf19.1709 || || || Sterol carrier domain protein; alkaline downregulated; colony morphology-related gene regulation by Ssn6; Spider biofilm induced || 1 2.04 1.98 -2.35 -2.35 -0.45 -0.36 -0.28 0.28 -3.13 -2.41 -0.32 -0.74 -2.41 -3.15
6822 || orf19.1652 || POX1-3 || || Predicted acyl-CoA oxidase; farnesol regulated; stationary phase enriched protein; Spider biofilm induced || 1 1.01 1.02 1.47 1.04 -0.96 -0.89 -0.52 -0.52 -0.40 -0.07 -1.96 -1.33 -0.40 -0.62 -1.36 -1.93
6823 || orf19.1652 || POX1-3 || || Predicted acyl-CoA oxidase; farnesol regulated; stationary phase enriched protein; Spider biofilm induced || 1 1.00 0.96 1.57 1.02 -0.98 -0.84 -0.35 -0.42 -0.39 0.02 -1.84 -0.94 -0.55 -0.25 -1.08 -1.16
6824 || orf19.2810 || AAP1 || || Putative amino acid permease; fungal-specific; possibly essential, disruptants not obtained by UAU1 method; Spider biofilm induced || 1 0.83 0.74 1.77 2.15 -1.60 -1.82 -0.91 -1.34 -0.01 0.08 -2.45 -1.73 -0.04 -0.24 -2.14 -2.27
6825 || orf19.2810 || AAP1 || || Putative amino acid permease; fungal-specific; possibly essential, disruptants not obtained by UAU1 method; Spider biofilm induced || 1 0.52 0.60 1.37 1.39 -1.58 -1.19 -0.90 -1.11 -0.43 0.18 -2.11 -1.74 -0.31 -0.44 -2.22 -1.51
6826 || orf19.3684 || || || Putative oxidoreductase; Spider biofilm induced || 1 0.20 0.16 1.30 1.97 -1.88 -1.72 -1.04 -0.73 -1.11 -0.18 -2.46 -1.98 0.19 -0.68 -2.00 -1.63
6827 || orf19.7668 || MAL2 || || Alpha-glucosidase; hydrolyzes sucrose for sucrose utilization; transcript regulated by Suc1, induced by maltose, repressed by glucose; Tn mutation affects filamentous growth; upregulated in RHE model; rat catheter and Spider biofilm induced || 1 0.12 0.27 0.87 0.95 -1.54 -1.27 -0.63 -0.15 0.31 0.23 -1.80 -1.00 -0.75 -0.15 -1.69 -1.52
6828 || orf19.3121 || GST1 || || Putative glutathione S-transferase; upregulated in the presence of human neutrophils; expression is regulated upon white-opaque switching; increased transcription is observed upon benomyl treatment || 1 0.81 0.58 1.26 1.19 -1.72 -1.92 -0.38 -0.71 0.29 0.58 -2.66 -2.21 -1.55 -0.87 -1.77 -2.24
6829 || orf19.4527 || HGT1 || || High-affinity MFS glucose transporter; induced by progesterone, chloramphenicol, benomyl; likely essential for growth; protein newly produced during adaptation to the serum; rat catheter and Spider biofilm induced || 1 0.97 0.80 1.39 0.85 -3.19 -2.73 -1.92 -1.70 -1.20 -0.71 -4.52 -3.29 -0.55 -1.16 -1.30 -3.17
6830 || orf19.3668 || HGT2 || || Putative MFS glucose transporter; 20 member C. albicans glucose transporter family; 12 probable membrane-spanning segments; expressed in rich medium with 2% glucose; rat catheter and Spider biofilm induced || 1 1.19 1.05 1.93 0.91 -3.38 -3.60 -1.98 -1.74 -0.63 0.17 -4.78 -5.36 -0.44 -0.32 -0.85 -4.76
6831 || orf19.4527 || HGT1 || || High-affinity MFS glucose transporter; induced by progesterone, chloramphenicol, benomyl; likely essential for growth; protein newly produced during adaptation to the serum; rat catheter and Spider biofilm induced || 1 1.23 1.28 2.33 1.43 -3.35 -3.51 -1.94 -1.72 -0.75 0.14 -5.98 -4.93 -0.32 -0.64 -1.10 -4.48
6832 || orf19.3668 || HGT2 || || Putative MFS glucose transporter; 20 member C. albicans glucose transporter family; 12 probable membrane-spanning segments; expressed in rich medium with 2% glucose; rat catheter and Spider biofilm induced || 1 1.17 1.29 2.13 1.35 -3.54 -3.83 -2.07 -1.91 -0.83 0.01 -6.43 -5.43 -0.36 -0.56 -0.92 -4.88
6833 || orf19.4527 || HGT1 || || High-affinity MFS glucose transporter; induced by progesterone, chloramphenicol, benomyl; likely essential for growth; protein newly produced during adaptation to the serum; rat catheter and Spider biofilm induced || 1 1.14 1.26 2.12 1.18 -3.76 -3.45 -1.93 -1.73 -0.65 0.29 -6.03 -5.07 -0.19 -0.26 -0.81 -4.32
6834 || orf19.3668 || HGT2 || || Putative MFS glucose transporter; 20 member C. albicans glucose transporter family; 12 probable membrane-spanning segments; expressed in rich medium with 2% glucose; rat catheter and Spider biofilm induced || 1 1.43 1.32 2.18 1.29 -3.37 -3.46 -1.68 -1.42 -0.57 0.13 -5.39 -5.06 -0.13 -0.26 -0.84 -3.99
6835 || orf19.4527 || HGT1 || || High-affinity MFS glucose transporter; induced by progesterone, chloramphenicol, benomyl; likely essential for growth; protein newly produced during adaptation to the serum; rat catheter and Spider biofilm induced || 1 1.34 1.30 1.21 -3.26 -3.60 -1.94 -1.68 -0.46 0.30 -5.44 -5.18 -0.00 -0.21 -0.54 -4.81
6836 || orf19.3668 || HGT2 || || Putative MFS glucose transporter; 20 member C. albicans glucose transporter family; 12 probable membrane-spanning segments; expressed in rich medium with 2% glucose; rat catheter and Spider biofilm induced || 1 1.41 1.50 2.27 1.36 -3.38 -3.67 -1.95 -1.74 -0.51 0.23 -6.00 -5.24 0.04 -0.18 -0.69 -5.12
6837 || orf19.3668 || HGT2 || || Putative MFS glucose transporter; 20 member C. albicans glucose transporter family; 12 probable membrane-spanning segments; expressed in rich medium with 2% glucose; rat catheter and Spider biofilm induced || 1 1.60 1.60 2.42 1.40 -2.82 -3.25 -1.75 -1.60 -0.27 0.27 -5.57 -5.07 0.11 -0.32 -0.74 -4.20
6838 || orf19.4527 || HGT1 || || High-affinity MFS glucose transporter; induced by progesterone, chloramphenicol, benomyl; likely essential for growth; protein newly produced during adaptation to the serum; rat catheter and Spider biofilm induced || 1 1.38 1.33 2.55 1.44 -2.81 -3.16 -1.61 -1.29 -0.37 0.39 -4.30 -4.38 -0.04 -0.10 -0.60 -4.21
6839 || orf19.7434 || GLG2 || || Putative self-glucosylating initiator of glycogen synthesis; expression regulated upon white-opaque switch; hypha-induced; Spider biofilm induced || 1 0.72 0.73 0.95 1.38 -1.57 -1.04 -1.03 -0.74 -0.67 0.41 -4.91 -3.21 0.12 0.03 -1.14 -3.53
6840 || orf19.4772 || SSU81 || || Predicted adaptor protein involved in activation of MAP kinase-dependent signaling pathways; links response to oxidative stress to morphogenesis and cell wall biosynthesis; caspofungin repressed || 1 0.27 0.06 0.35 0.21 -0.67 -0.66 -0.84 -0.96 -0.40 -0.19 -1.85 -1.65 0.15 -0.12 -0.75 -1.57
6841 || orf19.5604 || MDR1 || || Plasma membrane MDR/MFS multidrug efflux pump; methotrexate is preferred substrate; overexpression in drug-resistant clinical isolates confers fluconazole resistance; repressed in young biofilms; rat catheter biofilm induced || 1 1.16 0.97 -1.45 -1.33 -0.96 -0.91 -0.09 -0.74 -2.54 -2.37 1.02 0.27 -0.49 -3.13
6842 || orf19.5992 || WOR2 || || Zn(II)2Cys6 transcription factor; regulator of white-opaque switching; required for maintenance of opaque state; Hap43-induced || 1 1.18 0.98 -2.82 -1.57 -0.33 -0.82 0.26 -0.47 -3.38 -2.56 1.28 0.57 -0.62 -3.53
6843 || orf19.2202 || || || Protein of unknown function; induced by alpha pheromone in SpiderM medium || 1 0.02 0.18 0.73 0.88 -0.23 -0.20 -0.03 -0.26 0.08 0.04 -0.68 -0.94 -0.19 -0.57 -0.10 -0.94
6844 || orf19.854 || UGA11 || || Putative gamma-aminobutyrate (GABA) transaminase; macrophage-induced; overlaps orf19.854.1, which is a region annotated as a blocked reading frame; Spider biofilm induced || 1 0.50 0.72 1.25 1.47 -0.19 -1.22 0.53 0.32 -0.47 0.31 -0.33 -2.20 0.09 -1.41 -0.63 -2.11
6845 || orf19.2734 || || || Protein with a glucose/ribitol dehydrogenase family domain; mutants are viable || 1 0.93 1.50 1.49 2.22 -0.37 -1.05 0.28 0.23 -0.43 0.07 -0.98 -3.46 0.20 -1.07 -0.80 -2.37
6846 || orf19.1239 || || || Secreted protein; exogenously expressed protein is a substrate for Kex2 processing in vitro; fluconazole-regulated; Spider biofilm induced || 1 0.93 0.99 1.75 2.09 -0.78 -1.50 0.17 0.19 -0.86 0.77 -1.37 -2.84 0.26 -1.61 -0.74 -1.73
6847 || orf19.1239 || || || Secreted protein; exogenously expressed protein is a substrate for Kex2 processing in vitro; fluconazole-regulated; Spider biofilm induced || 1 0.90 0.94 1.66 2.10 0.18 -0.90 0.21 0.43 -0.71 0.45 -1.11 -2.59 0.23 -1.67 -0.53 -2.07
6848 || orf19.2734 || || || Protein with a glucose/ribitol dehydrogenase family domain; mutants are viable || 1 0.81 0.77 1.51 1.99 -0.07 -0.83 -0.09 0.16 -0.45 0.28 -0.55 -1.64 0.03 -0.95 -0.18 -1.53
6849 || orf19.6998 || GTT1 || || Putative glutathione S-transferase; downregulated upon adherence to polystyrene; regulated upon white-opaque switching; induced in the presence of human neutrophils; oxidative stress-induced via Cap1p; regulated by Gcn2p, Gcn4p || 1 0.83 1.14 1.24 2.04 -0.11 -2.49 -0.14 -0.11 -0.32 0.82 -0.70 -2.83 0.06 -0.74 -0.28 -1.75
6850 || orf19.532 || RBR2 || || Cell wall protein; expression repressed by Rim101; transcript regulated upon white-opaque switching; repressed by alpha pheromone in SpiderM medium; macrophage-induced gene || 1 0.55 0.73 1.53 2.49 -0.34 -1.45 -0.63 -0.46 -0.82 -0.02 -1.46 -2.50 0.21 -0.36 -0.73 -2.25
6851 || orf19.2253 || || || Protein of unknown function; expression regulated by white-opaque switch; repressed by alpha pheromone in SpiderM medium; Spider biofilm induced || 1 1.29 1.58 1.32 2.41 -0.61 -2.07 -0.95 -0.67 -1.82 -0.11 -2.05 -3.38 -0.10 -1.57 -0.81 -3.39
6852 || orf19.3330.3 || POX18 || || Similar to Pox18, a peroxisomal protein; induced during chlamydospore formation in C. albicans and C. dubliniensis; A21 sequence updated based on new sequence and analysis, the allelic orf19.10841 was reinstated; Spider biofilm induced || 1 1.85 2.00 2.59 2.79 -1.74 -3.56 -1.06 -1.12 -2.15 -0.09 -2.26 -2.84 -0.78 -2.14 -1.86 -2.48
6853 || orf19.3330.3 || POX18 || || Similar to Pox18, a peroxisomal protein; induced during chlamydospore formation in C. albicans and C. dubliniensis; A21 sequence updated based on new sequence and analysis, the allelic orf19.10841 was reinstated; Spider biofilm induced || 1 1.76 1.84 2.75 2.92 -1.20 -3.99 -0.63 -0.77 -1.77 -0.19 -1.67 -2.51 -0.52 -1.96 -1.50 -2.71
6854 || orf19.3330.3 || POX18 || || Similar to Pox18, a peroxisomal protein; induced during chlamydospore formation in C. albicans and C. dubliniensis; A21 sequence updated based on new sequence and analysis, the allelic orf19.10841 was reinstated; Spider biofilm induced || 1 1.81 1.74 2.66 2.82 -0.80 -3.67 -0.62 -0.88 -1.42 0.04 -1.99 -2.18 -0.11 -1.58 -1.58 -2.45
6855 || orf19.356 || GTT13 || || Putative glutathione S-transferase; opaque-specific transcript; repressed by alpha pheromone in SpiderM medium; Spider biofilm induced || 1 1.27 1.54 2.02 2.65 -0.44 -2.43 -0.68 -0.91 -1.51 -0.57 -1.37 -2.50 0.19 -2.23 -0.87 -2.42
6856 || orf19.7094 || HGT12 || || Glucose, fructose, mannose transporter; major facilitator superfamily; role in macrophage-induced hyphal growth; detected at germ tube plasma membrane by mass spectrometry; Snf3p-induced; 12 probable transmembrane segments || 1 1.69 1.28 2.13 2.62 -0.85 -2.03 -0.63 -0.45 -0.70 -0.42 -1.36 -2.16 -0.59 -2.77 -0.41 -2.12
6857 || orf19.3330.3 || POX18 || || Similar to Pox18, a peroxisomal protein; induced during chlamydospore formation in C. albicans and C. dubliniensis; A21 sequence updated based on new sequence and analysis, the allelic orf19.10841 was reinstated; Spider biofilm induced || 1 1.92 1.89 2.57 2.76 -0.32 -1.88 -0.52 -0.47 -1.07 -0.17 -1.03 -2.59 0.45 -1.98 -1.59 -1.57
6858 || orf19.3330.3 || POX18 || || Similar to Pox18, a peroxisomal protein; induced during chlamydospore formation in C. albicans and C. dubliniensis; A21 sequence updated based on new sequence and analysis, the allelic orf19.10841 was reinstated; Spider biofilm induced || 1 1.83 1.84 2.81 2.99 -0.75 -1.72 -0.21 0.07 -0.96 -0.41 -0.99 -2.68 -0.05 -2.02 -0.58 -1.80
6859 || orf19.356 || GTT13 || || Putative glutathione S-transferase; opaque-specific transcript; repressed by alpha pheromone in SpiderM medium; Spider biofilm induced || 1 1.21 1.34 1.97 2.85 0.15 -1.10 -0.26 -0.44 -0.60 -0.35 -0.51 -1.58 0.17 -1.02 -0.42 -1.02
6860 || orf19.7221 || SET3 || || NAD-dependent histone deacetylase; mutations affect filamentous growth; genetic evidence suggests Set3/Hos2 function as a complex to regulate white-opaque switching, morphogenesis, and virulence; flow model biofilm induced || 1 1.11 1.12 1.30 2.65 -0.47 -1.20 -0.23 -0.33 -1.10 -0.35 -0.82 -1.16 -0.08 -0.87 -0.41 -1.31
6861 || orf19.6518 || || || Predicted aldehyde dehydrogenase [NAD(P)+]; Spider biofilm induced || 1 0.94 1.07 1.23 1.85 -0.73 -0.97 -0.12 -0.04 -0.18 -0.10 -0.74 -1.01 -0.39 -0.66 -0.46 -1.07
6862 || orf19.7481 || MDH1 || || Mitochondrial malate dehydrogenase; regulated by Mig1, Tup1, white-opaque switch, phagocytosis; induced in high iron; antigenic during murine and human infection; repressed in Spider biofilms by Bcr1, Tec1, Ndt80, Rob1, Brg1 || 1 0.97 1.00 1.61 1.85 -0.59 -1.01 -0.30 0.11 -0.27 -0.25 -1.33 -1.10 -0.58 -0.61 -0.59 -1.46
6863 || orf19.6830 || || || Putative enoyl-CoA hydratase; Spider biofilm induced || 1 1.23 1.07 1.72 2.17 -0.47 -0.85 -0.37 -0.46 -0.09 0.21 -1.52 -1.37 -0.78 -0.61 -1.30 -1.54
6864 || orf19.7627 || || || Ortholog(s) have role in establishment of cell polarity, mycelium development, spore germination and endoplasmic reticulum, hyphal tip, mitochondrion, plasma membrane localization || 1 0.47 0.45 0.52 0.61 -0.14 -0.37 -0.13 -0.14 -0.01 0.17 -0.63 -0.57 -0.25 -0.32 -0.11 -0.38
6865 || orf19.2734 || || || Protein with a glucose/ribitol dehydrogenase family domain; mutants are viable || 1 1.28 1.57 1.70 2.40 -0.21 -1.64 -0.23 0.04 -0.33 0.44 -2.47 -2.25 -0.03 -1.02 -1.38 -1.84
6866 || orf19.7668 || MAL2 || || Alpha-glucosidase; hydrolyzes sucrose for sucrose utilization; transcript regulated by Suc1, induced by maltose, repressed by glucose; Tn mutation affects filamentous growth; upregulated in RHE model; rat catheter and Spider biofilm induced || 1 0.60 0.58 0.99 0.99 -0.46 -0.81 0.02 0.03 0.20 0.14 -0.94 -1.03 -0.30 0.03 -0.55 -1.21
6867 || orf19.3418 || || || Ortholog(s) have endoplasmic reticulum, fungal-type vacuole localization || 1 0.43 0.45 1.18 1.51 -0.36 -0.37 -0.11 -0.16 -0.05 0.11 -1.26 -1.34 -0.34 -0.04 -0.34 -1.28
6868 || orf19.2734 || || || Protein with a glucose/ribitol dehydrogenase family domain; mutants are viable || 1 0.39 0.54 1.70 2.48 -0.69 -0.71 -0.23 -0.06 -0.29 0.22 -1.16 -1.79 -0.37 -0.34 -0.73 -1.67
6869 || orf19.2168 || || || Putative sterol deacetylase; flow model biofilm induced; rat catheter biofilm repressed || 1 0.25 0.33 1.38 1.87 -0.31 -1.28 -0.22 -0.30 0.11 0.22 -1.89 -1.19 -0.08 -0.76 -1.13 -1.42
6870 || orf19.10 || ALK8 || || Alkane-inducible cytochrome P450; catalyzes hydroxylation of lauric acid to hydroxylauric acid; overproduction causes fluconazole resistance in WT and causes multidrug resistance in a cdr1 cdr2 double mutant; rat catheter biofilm repressed || 1 1.26 1.16 1.90 1.78 -0.35 -0.92 0.11 -0.55 0.34 0.11 -2.38 -2.47 -0.18 -1.88 -0.63 -2.43
6871 || orf19.6518 || || || Predicted aldehyde dehydrogenase [NAD(P)+]; Spider biofilm induced || 1 0.29 0.40 1.58 1.60 -0.58 -0.92 -0.36 -0.38 0.29 -0.07 -1.16 -1.62 -0.03 -0.93 -0.78 -1.12
6872 || orf19.6518 || || || Predicted aldehyde dehydrogenase [NAD(P)+]; Spider biofilm induced || 1 0.52 0.70 1.33 1.71 -0.26 -1.04 -0.38 -0.38 -0.29 -0.16 -1.27 -1.86 0.05 -1.31 -0.79 -1.39
6873 || orf19.5307 || JEN2 || || Dicarboxylic acid transporter; regulated by glucose repression; induced by Rgt1; disruptants not obtained by UAU1 method; rat catheter and Spider biofilm induced || 1 1.26 1.15 2.17 2.33 -1.15 -1.62 -0.96 -1.26 -0.55 0.38 -1.74 -2.47 -0.57 -1.87 -1.15 -1.40
6874 || orf19.10 || ALK8 || || Alkane-inducible cytochrome P450; catalyzes hydroxylation of lauric acid to hydroxylauric acid; overproduction causes fluconazole resistance in WT and causes multidrug resistance in a cdr1 cdr2 double mutant; rat catheter biofilm repressed || 1 1.53 1.47 2.24 2.36 -0.46 -1.61 -1.26 -1.38 -0.59 0.19 -2.62 -3.26 -0.76 -2.29 -1.47 -2.10
6875 || orf19.10 || ALK8 || || Alkane-inducible cytochrome P450; catalyzes hydroxylation of lauric acid to hydroxylauric acid; overproduction causes fluconazole resistance in WT and causes multidrug resistance in a cdr1 cdr2 double mutant; rat catheter biofilm repressed || 1 1.54 1.25 2.04 1.94 -0.53 -2.48 -1.20 -1.39 -0.19 -0.10 -2.48 -3.79 -1.30 -2.52 -1.63 -2.54
6876 || orf19.5303 || PGA30 || || GPI-anchored protein of cell wall || 1 1.54 1.51 2.60 2.57 -1.08 -2.08 -1.19 -1.66 0.02 -0.67 -2.12 -2.65 -1.28 -2.47 -1.99 -3.14
6877 || orf19.10 || ALK8 || || Alkane-inducible cytochrome P450; catalyzes hydroxylation of lauric acid to hydroxylauric acid; overproduction causes fluconazole resistance in WT and causes multidrug resistance in a cdr1 cdr2 double mutant; rat catheter biofilm repressed || 1 1.01 1.06 2.12 1.87 -0.61 -1.68 -1.14 -1.57 0.23 0.60 -3.56 -2.25 -1.12 -1.98 -1.64 -2.50
6878 || orf19.10 || ALK8 || || Alkane-inducible cytochrome P450; catalyzes hydroxylation of lauric acid to hydroxylauric acid; overproduction causes fluconazole resistance in WT and causes multidrug resistance in a cdr1 cdr2 double mutant; rat catheter biofilm repressed || 1 0.82 1.04 1.72 1.50 -0.71 -2.39 -1.25 -1.56 -0.07 0.45 -4.54 -2.95 -1.47 -2.49 -1.84 -2.65
6879 || orf19.1766 || || || Secreted protein; fluconazole-induced || 1 1.23 1.19 1.55 2.49 -1.15 -2.15 -0.69 -0.65 0.06 0.54 -4.01 -4.05 -2.19 -4.06 -2.16 -3.39
6880 || orf19.7094 || HGT12 || || Glucose, fructose, mannose transporter; major facilitator superfamily; role in macrophage-induced hyphal growth; detected at germ tube plasma membrane by mass spectrometry; Snf3p-induced; 12 probable transmembrane segments || 1 0.28 0.71 1.72 2.46 -0.52 -1.81 -0.93 -1.11 -1.16 -0.52 -1.59 -3.08 -0.23 -2.96 -1.08 -2.70
6881 || orf19.7539.1 || || || Putative adhesin-like protein; transcription detected in high-resolution tiling array experiments || 1 0.37 0.60 1.22 2.06 0.35 -0.58 -0.43 -0.44 -0.49 0.34 -0.52 -0.81 0.23 -0.83 -0.25 -1.14
6882 || orf19.6336 || PGA25 || || Putative GPI-anchored adhesin-like protein; fluconazole-downregulated; induced in oralpharyngeal candidasis; Spider biofilm induced || 1 0.25 0.55 1.11 2.16 0.42 -0.42 -0.51 -0.52 -0.21 0.01 -0.50 -0.87 0.22 -0.84 -0.31 -0.98
6883 || orf19.5728 || || || Putative cytochrome P450; Spider biofilm induced || 1 1.07 1.20 1.91 2.31 0.21 -0.77 -0.83 -0.78 -0.10 -0.21 -1.13 -1.58 0.30 -1.33 -0.57 -1.39
6884 || orf19.1704 || FOX3 || || Putative peroxisomal 3-oxoacyl CoA thiolase; transcript regulated by white-opaque switch; Spider biofilm induced || 1 0.65 0.80 1.60 1.89 0.02 -0.52 -0.65 -0.60 -0.04 -0.13 -0.67 -0.70 0.04 -0.48 -0.30 -1.02
6885 || orf19.3232 || || || Putative transporter; mutation confers hypersensitivity to toxic ergosterol analog; fungal-specific (no human or murine homolog) || 1 0.68 1.01 1.40 2.10 -0.36 -1.01 -0.57 -0.75 -0.54 -0.14 -1.06 -0.49 -0.30 -1.17 -0.77 -0.82
6886 || orf19.6678 || || || Protein of unknown function; Hap43-repressed gene || 1 0.94 1.06 2.21 2.54 -0.53 -1.27 -0.30 -0.35 0.18 -0.96 -1.08 -1.48 0.04 -0.70 -0.90 -1.23
6887 || orf19.5503 || || || Putative protein of unknown function; transcript is upregulated in clinical isolates from HIV+ patients with oral candidiasis; Spider biofilm induced || 1 1.26 1.51 3.18 2.22 -1.18 -2.29 -1.03 -0.84 -0.54 -0.80 -1.91 -2.34 1.27 -1.60 -1.04 -2.58
6888 || orf19.5503 || || || Putative protein of unknown function; transcript is upregulated in clinical isolates from HIV+ patients with oral candidiasis; Spider biofilm induced || 1 1.59 2.08 3.26 2.08 -2.00 -2.06 -2.17 -2.41 -1.22 -0.78 -2.73 -3.95 1.67 -1.39 -2.04
6889 || orf19.801 || TBF1 || || Essential transcription factor; induces ribosomal protein genes and the rDNA locus; acts with Cbf1 at subset of promoters; recruits Fhl1 and Ifh1 to promoters; role is analogous to that of S. cerevisiae Rap1; Spider biofilm induced || 1 0.35 0.43 0.76 1.88 -0.59 -0.47 -0.45 -0.68 -1.21 -0.32 -0.64 -1.04 -0.12 -0.81 -0.68 -0.77
6890 || orf19.7539.1 || || || Putative adhesin-like protein; transcription detected in high-resolution tiling array experiments || 1 0.54 0.58 0.50 2.41 -0.68 -1.18 -0.89 -0.81 -0.99 0.21 -0.76 -1.28 -0.44 -1.61 -0.74 -1.21
6891 || orf19.7539.1 || || || Putative adhesin-like protein; transcription detected in high-resolution tiling array experiments || 1 0.38 0.38 1.01 2.18 -0.77 -0.87 -0.70 -0.70 -1.09 0.12 -0.97 -1.18 -0.77 -1.20 -0.51 -0.69
6892 || orf19.6336 || PGA25 || || Putative GPI-anchored adhesin-like protein; fluconazole-downregulated; induced in oralpharyngeal candidasis; Spider biofilm induced || 1 0.45 0.53 1.10 2.34 -0.64 -1.26 -0.90 -0.83 -1.32 0.01 -0.83 -1.16 -0.71 -1.45 -0.72 -0.88
6893 || orf19.6336 || PGA25 || || Putative GPI-anchored adhesin-like protein; fluconazole-downregulated; induced in oralpharyngeal candidasis; Spider biofilm induced || 1 0.37 0.42 1.16 2.27 -0.67 -1.00 -0.86 -0.86 -1.02 0.10 -0.77 -1.18 -0.86 -1.34 -0.80 -1.09
6894 || orf19.7447 || JEN1 || || Lactate transporter; induced by lactic acid, activated by Cat8; alkaline repressed by Rim101; localizes to plasma membrane; Spider biofilm induced || 1 0.62 0.41 1.20 2.09 -0.73 -1.04 -0.67 -0.62 -0.87 0.14 -1.07 -1.52 -0.74 -1.48 -0.63 -1.28
6895 || orf19.7447 || JEN1 || || Lactate transporter; induced by lactic acid, activated by Cat8; alkaline repressed by Rim101; localizes to plasma membrane; Spider biofilm induced || 1 0.81 0.66 1.62 2.80 -0.92 -1.68 -0.78 -0.72 -0.86 0.19 -0.97 -1.94 -1.46 -1.90 -1.10 -1.46
6896 || orf19.7539.1 || || || Putative adhesin-like protein; transcription detected in high-resolution tiling array experiments || 1 0.29 0.51 0.52 1.99 -1.40 -1.75 -1.33 -1.26 -1.77 -0.30 -1.26 -1.64 -1.75 -1.71 -1.37 -1.25
6897 || orf19.6336 || PGA25 || || Putative GPI-anchored adhesin-like protein; fluconazole-downregulated; induced in oralpharyngeal candidasis; Spider biofilm induced || 1 0.40 0.27 0.71 1.98 -1.56 -1.54 -1.54 -1.15 -1.89 -0.27 -1.12 -1.73 -1.61 -1.64 -1.36 -1.95
6898 || orf19.7517 || CHT1 || || Chitinase; putative N-terminal catalytic domain; has secretory signal sequence; lacks S/T region and N-glycosylation motifs of Chs2p and Chs3p; alkaline downregulated; expression not detected in yeast-form or hyphal cells || 1 0.70 0.83 1.44 2.74 -1.37 -2.76 -0.70 -0.25 -1.91 -0.25 -0.58 -1.65 -1.15 -1.51 -1.20 -1.66
6899 || orf19.7517 || CHT1 || || Chitinase; putative N-terminal catalytic domain; has secretory signal sequence; lacks S/T region and N-glycosylation motifs of Chs2p and Chs3p; alkaline downregulated; expression not detected in yeast-form or hyphal cells || 1 1.02 1.20 1.28 2.55 -1.37 -2.40 -0.62 0.07 -2.32 0.00 -0.73 -1.67 -1.24 -1.41 -1.05 -1.20
6900 || orf19.7608 || || || Protein of unknown function; fluconazole-repressed; Spider biofilm induced || 1 1.03 1.25 2.26 3.29 -1.04 -3.36 -0.75 -0.85 -3.89 -1.80 -0.69 -0.93 -1.23 -2.13 -0.66 -0.60
6901 || orf19.7608 || || || Protein of unknown function; fluconazole-repressed; Spider biofilm induced || 1 1.24 1.29 2.17 2.91 -1.53 -3.51 -0.81 -0.87 -3.02 -1.82 -0.80 -1.28 -0.79 -4.34 -0.96 -1.72
6902 || orf19.7608 || || || Protein of unknown function; fluconazole-repressed; Spider biofilm induced || 1 1.12 0.80 2.36 3.15 -0.27 -2.71 -1.11 -1.09 -1.76 -2.42 -0.51 -2.16 -0.82 -2.69 -1.26 -1.93
6903 || orf19.7608 || || || Protein of unknown function; fluconazole-repressed; Spider biofilm induced || 1 1.24 1.37 2.57 3.21 -0.50 -2.55 -1.21 -1.13 -2.48 -1.51 0.12 -2.82 -1.00 -2.54 -1.39 -2.19
6904 || orf19.6336 || PGA25 || || Putative GPI-anchored adhesin-like protein; fluconazole-downregulated; induced in oralpharyngeal candidasis; Spider biofilm induced || 1 -0.02 0.11 0.82 1.87 0.15 -0.98 -0.51 -0.70 -0.82 -0.26 -0.43 -1.22 -0.23 -1.20 -0.11 -1.09
6905 || orf19.7539.1 || || || Putative adhesin-like protein; transcription detected in high-resolution tiling array experiments || 1 0.03 -0.02 0.66 1.78 -0.12 -0.93 -0.40 -0.60 -0.90 -0.12 -0.20 -1.14 -0.27 -1.21 0.19 -0.77
6906 || orf19.7608 || || || Protein of unknown function; fluconazole-repressed; Spider biofilm induced || 1 1.07 0.84 1.95 3.14 -0.95 -1.89 -1.04 0.58 -1.43 -1.35 -0.75 -3.75 -0.63 -3.73 -1.07 -2.22
6907 || orf19.7447 || JEN1 || || Lactate transporter; induced by lactic acid, activated by Cat8; alkaline repressed by Rim101; localizes to plasma membrane; Spider biofilm induced || 1 0.74 1.24 1.15 2.43 0.05 -1.67 -0.53 -0.21 -1.44 0.12 -0.15 -0.99 0.04 -2.57 -0.77 -1.26
6908 || orf19.6896 || || || Predicted ORF overlapping the Major Repeat Sequence on chromosome 7; member of a family encoded by FGR6-related genes in the RB2 repeat sequence || 1 0.34 0.04 0.47 0.51 -0.37 -0.94 -0.39 0.29 0.07 -0.00 -0.40 -0.53 0.09 -0.21 -0.63 -0.36
6909 || orf19.5958 || CDR2 || || Multidrug transporter, ATP-binding cassette (ABC) superfamily; transports phospholipids, in-to-out direction; overexpressed in azole-resistant isolates; repressed in young biofilms || 1 0.58 -0.25 -0.26 0.01 -0.50 -0.45 -0.28 -0.02 0.38 -0.05 -0.58 -0.39 -0.60 -0.32 -0.84 -0.38
6910 || orf19.271 || ADH4 || || Predicted 3-hydroxyacyl-CoA dehydrogenase; transcript is increased in azole-resistant strain overexpressing MDR1; transcript is increased in populations of cells exposed to fluconazole over multiple generations; mutant is viable || 1 0.47 0.62 -0.26 0.87 -0.81 -1.32 0.03 -0.11 -0.18 1.11 -1.13 -0.38 -0.80 -1.30 -1.35 -0.41
6911 || orf19.6855 || || || Ortholog of C. dubliniensis CD36 : Cd36_04370, C. parapsilosis CDC317 : CPAR2_105410, Candida tenuis NRRL Y-1498 : CANTEDRAFT_114891 and Debaryomyces hansenii CBS767 : DEHA2D13420g || 1 0.45 0.41 0.05 0.34 -0.56 -0.86 -0.19 -0.08 0.33 1.11 -0.57 -0.43 -0.65 -0.35 -0.95 -1.09
6912 || orf19.6855 || || || Ortholog of C. dubliniensis CD36 : Cd36_04370, C. parapsilosis CDC317 : CPAR2_105410, Candida tenuis NRRL Y-1498 : CANTEDRAFT_114891 and Debaryomyces hansenii CBS767 : DEHA2D13420g || 1 -0.25 -0.05 -0.17 0.29 -0.82 -1.12 -0.54 -0.01 0.41 1.04 -0.92 -0.41 -0.86 -0.63 -1.05 -1.01
6913 || orf19.4162 || MLH1 || || Putative mismatch repair protein; cell-cycle regulated periodic mRNA expression || 1 0.02 0.14 -0.20 0.50 -0.26 -0.73 -0.41 -0.34 -0.16 0.73 -0.91 -0.52 -0.24 -0.70 -0.87
6914 || orf19.1327 || RBT1 || || Cell wall protein with similarity to Hwp1; required for virulence; predicted glycosylation; fluconazole, Tup1 repressed; farnesol, alpha factor, serum, hyphal and alkaline induced; Rfg1, Rim101-regulated || 1 -0.14 -0.20 -1.63 -0.32 -1.38 -1.09 0.03 -1.40 0.48 0.27 -2.31 -1.75 -1.83 -1.94 -0.74 -1.04
6915 || orf19.815 || DCK1 || || Putative guanine nucleotide exchange factor; required for embedded filamentous growth; activates Rac1; has a DOCKER domain; similar to adjacent DCK2 and to S. cerevisiae Ylr422wp; regulated by Nrg1; Spider biofilm induced || 1 0.24 0.04 -0.10 0.06 -0.94 -1.29 0.03 -0.23 0.23 0.36 -0.77 -0.61 -0.23 -0.49 -0.49 -0.68
6916 || orf19.6705 || || || Putative guanyl nucleotide exchange factor with Sec7 domain; required for normal filamentous growth; regulated by yeast-hyphal switch; filament induced; regulated by Nrg1, Tup1, Mob2, Hap43; mRNA binds She3; Spider biofilm induced || 1 0.08 -0.07 -0.49 -0.03 -0.95 -1.45 0.00 -0.39 0.17 1.04 -0.33 -0.80 0.16 -0.52 -0.82 -1.34
6917 || orf19.3501 || || || S. cerevisiae ortholog Pxl1 localizes to sites of polarized growth and is required for selection and/or maintenance of polarized growth sites; Hog1p-repressed || 1 -0.04 0.18 -0.65 -0.26 -0.69 -1.90 -0.06 -0.21 0.19 0.93 -0.58 -1.28 0.01 -0.60 -0.57 -1.26
6918 || orf19.3501 || || || S. cerevisiae ortholog Pxl1 localizes to sites of polarized growth and is required for selection and/or maintenance of polarized growth sites; Hog1p-repressed || 1 0.07 -0.09 -1.09 -0.31 -1.10 -2.13 0.28 0.29 0.25 0.80 -0.85 -1.62 -0.36 -0.70 -0.56 -1.88
6919 || orf19.6693 || || || Ortholog(s) have cytosol, nucleus localization || 1 -0.01 0.13 -0.54 0.13 -1.50 -1.51 0.09 0.25 0.17 1.16 -1.06 -1.40 -0.06 -0.53 -0.98 -1.41
6920 || orf19.929 || || || Protein of unknown function; rat catheter biofilm repressed || 1 0.07 -0.20 -1.19 -0.37 -1.97 -2.89 0.70 0.32 0.49 1.34 -3.15 -4.87 -1.58 -2.02 -2.70 -4.39
6921 || orf19.929 || || || Protein of unknown function; rat catheter biofilm repressed || 1 0.25 0.17 -0.60 -0.11 -1.37 -1.92 0.53 0.25 0.88 1.18 -1.92 -2.31 -1.16 -1.77 -1.17 -1.86
6922 || orf19.1822 || UME6 || || Zn(II)2Cys6 transcription factor; role in hyphal extension, virulence, adherence to plastic; filament induced; regulated by Nrg1/Tup1/Rfg1, alkaline conditions; expression promotes highly filamentous biofilms; rat catheter biofilm induced || 1 0.96 0.82 -1.20 0.47 -2.27 -4.81 1.03 1.06 1.12 1.93 -2.97 -4.36 -1.89 -2.81 -2.54 -4.35
6923 || orf19.1822 || UME6 || || Zn(II)2Cys6 transcription factor; role in hyphal extension, virulence, adherence to plastic; filament induced; regulated by Nrg1/Tup1/Rfg1, alkaline conditions; expression promotes highly filamentous biofilms; rat catheter biofilm induced || 1 0.57 0.74 -1.46 0.09 -2.00 -3.96 1.07 1.13 1.03 1.53 -2.25 -4.74 -1.74 -3.08 -2.31 -4.05
6924 || orf19.6028 || HGC1 || || Hypha-specific G1 cyclin-related protein involved in regulation of morphogenesis, biofilm formation; Cdc28-Hgc1 maintains Cdc11 S394 phosphorylation during hyphal growth; required for virulence in mice; regulated by Nrg1, Tup1, farnesol || 1 1.43 1.30 -0.70 0.14 -2.42 0.85 0.49 0.79 1.79 -2.47 -4.12 -0.87 -2.38 -1.61 -2.68
6925 || orf19.1822 || UME6 || || Zn(II)2Cys6 transcription factor; role in hyphal extension, virulence, adherence to plastic; filament induced; regulated by Nrg1/Tup1/Rfg1, alkaline conditions; expression promotes highly filamentous biofilms; rat catheter biofilm induced || 1 0.93 0.77 -0.66 0.34 -0.87 -2.37 0.76 0.90 1.04 1.51 -1.22 -2.51 -0.69 -2.19 -0.89 -1.57
6926 || orf19.6028 || HGC1 || || Hypha-specific G1 cyclin-related protein involved in regulation of morphogenesis, biofilm formation; Cdc28-Hgc1 maintains Cdc11 S394 phosphorylation during hyphal growth; required for virulence in mice; regulated by Nrg1, Tup1, farnesol || 1 1.29 1.04 -0.84 0.28 -2.06 -4.16 1.01 0.16 0.84 1.48 -0.69 -4.12 -1.12 -2.93 -2.57 -4.18
6927 || orf19.1321 || HWP1 || || Hyphal cell wall protein; host transglutaminase substrate; opaque-, a-specific, alpha-factor induced; at MTLa side of conjugation tube; virulence complicated by URA3 effects; Bcr1-repressed in RPMI a/a biofilms; Spider biofilm induced || 1 0.42 0.29 -0.23 0.04 -0.75 -1.73 0.11 -0.65 1.03 0.80 -1.07 -1.41 -0.50 -1.86 -0.89 -1.33
6928 || orf19.1321 || HWP1 || || Hyphal cell wall protein; host transglutaminase substrate; opaque-, a-specific, alpha-factor induced; at MTLa side of conjugation tube; virulence complicated by URA3 effects; Bcr1-repressed in RPMI a/a biofilms; Spider biofilm induced || 1 0.18 0.02 -3.24 -1.04 -2.62 -5.13 0.98 -1.57 1.30 1.03 -2.98 -3.38 -2.73 -5.19 -2.85 -4.05
6929 || orf19.1321 || HWP1 || || Hyphal cell wall protein; host transglutaminase substrate; opaque-, a-specific, alpha-factor induced; at MTLa side of conjugation tube; virulence complicated by URA3 effects; Bcr1-repressed in RPMI a/a biofilms; Spider biofilm induced || 1 -0.13 -0.23 -3.96 -0.79 -3.01 -4.64 1.20 -1.64 1.53 1.21 -4.00 -6.44 -3.41 -5.59 -3.27 -4.43
6930 || orf19.1321 || HWP1 || || Hyphal cell wall protein; host transglutaminase substrate; opaque-, a-specific, alpha-factor induced; at MTLa side of conjugation tube; virulence complicated by URA3 effects; Bcr1-repressed in RPMI a/a biofilms; Spider biofilm induced || 1 -0.48 -0.60 -3.32 -0.93 -2.26 -4.20 0.39 -1.67 1.18 0.98 -2.96 -5.39 -2.18 -5.38 -2.23 -3.77
6931 || orf19.929 || || || Protein of unknown function; rat catheter biofilm repressed || 1 -0.25 -0.16 -1.37 -0.04 -2.09 -2.88 0.70 0.23 1.23 1.86 -4.86 -3.04 -1.64 -2.26 -3.18 -2.27
6932 || orf19.318 || || || Ortholog(s) have role in iron-sulfur cluster assembly and mitochondrial matrix localization || 1 -0.22 -0.18 -0.18 -0.07 -0.19 -0.78 -0.04 0.12 -0.09 -0.07 -0.62 -0.60 -0.30 -0.17 -0.36 -0.61
6933 || orf19.4495 || NDH51 || || Nicotinamide adenine dinucleotide dehydrogenase complex I subunit of the mitochondrial electron transport chain; required for wild-type filamentous growth; alkaline repressed; Hap43-repressed; Spider biofilm repressed || 1 -0.13 -0.15 -0.76 -0.59 -1.12 -0.81 -0.36 -0.21 -0.50 0.11 -1.22 -1.29 -1.18 -1.26 -0.70 -1.42
6934 || orf19.1471 || COX4 || || Putative cytochrome c oxidase subunit IV; Mig1-regulated; macrophage/pseudohyphal-induced gene; macrophage-induced protein; repressed by nitric oxide; 5'-UTR intron; Hap43-repressed || 1 -0.20 -0.26 -0.79 -1.00 -0.88 -0.59 0.17 -0.15 0.06 -0.23 -1.09 -0.83 -0.43 -0.14 -0.79 -0.47
6935 || orf19.2304 || || || Protein similar to S. cerevisiae Gvp36p; transposon mutation affects filamentous growth || 1 -0.09 -0.16 -0.40 -0.62 -0.81 -0.84 0.06 -0.12 -0.20 -0.08 -0.64 -0.55 -0.71 -0.06 -0.68 -0.38
6936 || orf19.2644 || QCR2 || || Ubiquinol-cytochrome-c reductase; antigenic; induced by interaction with macrophage; repressed by nitric oxide; in detergent-resistant membrane fraction (possible lipid raft component); levels decrease in stationary phase; Hap43p-repressed || 1 -0.50 -0.52 -0.73 -0.55 -1.19 -1.05 -0.02 -0.17 -0.26 -0.21 -1.12 -1.08 -0.94 -0.85 -1.36 -0.98
6937 || orf19.1471 || COX4 || || Putative cytochrome c oxidase subunit IV; Mig1-regulated; macrophage/pseudohyphal-induced gene; macrophage-induced protein; repressed by nitric oxide; 5'-UTR intron; Hap43-repressed || 1 -0.36 -0.40 -0.40 -0.61 -1.07 -0.61 0.08 -0.40 -0.14 -0.44 -1.30 -1.04 -0.63 -0.47 -1.14 -0.53
6938 || orf19.1082.1 || || || Ortholog(s) have cytochrome-c oxidase activity, role in mitochondrial respiratory chain complex IV assembly and cytosol, mitochondrial intermembrane space, mitochondrial respiratory chain complex IV, nucleus localization || 1 -0.15 -0.32 -0.34 -0.44 -1.18 -0.53 -0.18 -0.44 -0.19 -0.42 -1.64 -1.36 -0.44 -0.43 -1.35 -1.05
6939 || orf19.7644 || || || Ortholog(s) have ubiquitin-protein ligase activity, role in anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process, protein ubiquitination and anaphase-promoting complex localization || 1 -0.34 -0.64 -0.35 -0.11 -1.41 -1.19 0.08 0.35 0.12 -0.25 -0.55 -0.74 -0.55 -0.19 -1.29 -0.46
6940 || orf19.873.1 || COX6 || || Putative cytochrome c oxidase; flucytosine induced || 1 -0.08 -0.12 -0.17 -0.51 -0.52 -0.55 0.24 0.18 0.31 -0.00 -0.83 -0.82 -0.63 -0.32 -1.03 -0.80
6941 || orf19.2644 || QCR2 || || Ubiquinol-cytochrome-c reductase; antigenic; induced by interaction with macrophage; repressed by nitric oxide; in detergent-resistant membrane fraction (possible lipid raft component); levels decrease in stationary phase; Hap43p-repressed || 1 -0.08 -0.11 -0.17 -0.53 -0.85 -0.80 0.25 0.25 0.21 0.34 -0.82 -0.89 -0.66 -0.40 -0.96 -0.89
6942 || orf19.2644 || QCR2 || || Ubiquinol-cytochrome-c reductase; antigenic; induced by interaction with macrophage; repressed by nitric oxide; in detergent-resistant membrane fraction (possible lipid raft component); levels decrease in stationary phase; Hap43p-repressed || 1 -0.14 -0.29 -0.33 -0.13 -1.14 -0.82 0.15 0.13 0.37 0.07 -0.87 -0.88 -0.77 -0.13 -1.13 -0.87
6943 || orf19.2644 || QCR2 || || Ubiquinol-cytochrome-c reductase; antigenic; induced by interaction with macrophage; repressed by nitric oxide; in detergent-resistant membrane fraction (possible lipid raft component); levels decrease in stationary phase; Hap43p-repressed || 1 -0.31 -0.21 -0.32 -0.08 -1.15 -0.87 0.17 0.13 0.22 0.15 -0.96 -0.78 -0.81 -0.39 -0.98 -0.82
6944 || orf19.2644 || QCR2 || || Ubiquinol-cytochrome-c reductase; antigenic; induced by interaction with macrophage; repressed by nitric oxide; in detergent-resistant membrane fraction (possible lipid raft component); levels decrease in stationary phase; Hap43p-repressed || 1 0.02 -0.15 -0.02 0.11 -1.05 -0.77 0.27 0.28 0.23 0.03 -0.85 -0.77 -0.69 -0.52 -1.21 -0.87
6945 || orf19.3527 || CYT1 || || Cytochrome c1; induced in high iron; alkaline repressed; possibly an essential gene, disruptants not obtained by UAU1 method; Hap43-repressed; Spider biofilm repressed || 1 -0.53 -0.49 -0.50 -0.42 -1.63 -1.30 0.41 0.28 0.37 0.21 -0.55 -0.62 -0.91 -0.58 -0.90 -0.68
6946 || orf19.3527 || CYT1 || || Cytochrome c1; induced in high iron; alkaline repressed; possibly an essential gene, disruptants not obtained by UAU1 method; Hap43-repressed; Spider biofilm repressed || 1 -0.47 -0.52 -0.61 -0.33 -1.61 -1.34 0.30 0.24 0.29 0.15 -0.57 -0.57 -0.95 -0.60 -1.06 -0.70
6947 || orf19.3527 || CYT1 || || Cytochrome c1; induced in high iron; alkaline repressed; possibly an essential gene, disruptants not obtained by UAU1 method; Hap43-repressed; Spider biofilm repressed || 1 -0.37 -0.53 -0.67 -0.42 -1.70 -1.35 0.33 0.32 0.10 -0.06 -0.54 -0.39 -1.05 -0.69 -1.04 -0.85
6948 || orf19.5893 || RIP1 || || Putative ubiquinol cytochrome c-reductase; induced by high iron; Hap43, nitric oxide, alkaline repressed; Spider biofilm repressed || 1 -0.15 -0.31 -0.33 -0.17 -1.45 -0.91 0.14 0.09 0.09 0.13 -0.77 -0.62 -0.87 -0.57 -0.74 -0.81
6949 || orf19.5893 || RIP1 || || Putative ubiquinol cytochrome c-reductase; induced by high iron; Hap43, nitric oxide, alkaline repressed; Spider biofilm repressed || 1 -0.02 -0.20 -0.38 -0.25 -1.34 -0.77 0.43 0.31 0.23 0.14 -0.52 -0.48 -0.53 -0.42 -0.59 -0.65
6950 || orf19.5893 || RIP1 || || Putative ubiquinol cytochrome c-reductase; induced by high iron; Hap43, nitric oxide, alkaline repressed; Spider biofilm repressed || 1 -0.18 -0.28 -0.79 -0.59 -1.51 -1.21 0.54 0.17 0.00 0.21 -0.71 -1.06 -0.55 -0.90 -0.79 -0.84
6951 || orf19.5893 || RIP1 || || Putative ubiquinol cytochrome c-reductase; induced by high iron; Hap43, nitric oxide, alkaline repressed; Spider biofilm repressed || 1 -0.24 -0.36 -0.85 -0.74 -1.60 -1.46 0.35 -0.00 -0.25 -0.27 -0.87 -1.20 -0.90 -1.09 -1.05 -1.01
6952 || orf19.1710 || ALI1 || || Putative NADH-ubiquinone oxidoreductase; in detergent-resistant membrane fraction (possible lipid raft component); predicted N-terminal acetylation; nitric oxide-repressed; plasma membrane-localized; protein decreases in stationary phase || 1 -0.02 -0.03 -0.12 -0.23 -1.26 -0.93 0.18 0.41 0.00 0.32 -1.03 -0.36 -1.23 -0.90 -0.91 -0.79
6953 || orf19.287 || || || Putative NADH-ubiquinone oxidoreductase subunit; Hap43p-repressed gene; repressed by nitric oxide; identified in detergent-resistant membrane fraction (possible lipid raft component) || 1 0.05 -0.03 -0.54 -0.42 -0.59 -0.61 -0.10 0.30 -0.44 0.12 -0.28 -0.31 -1.19 -0.16 -0.57 -0.61
6954 || orf19.287 || || || Putative NADH-ubiquinone oxidoreductase subunit; Hap43p-repressed gene; repressed by nitric oxide; identified in detergent-resistant membrane fraction (possible lipid raft component) || 1 0.06 -0.02 -0.51 -0.55 -0.69 -0.80 -0.16 0.15 -0.39 0.12 -0.50 -0.65 -1.08 -0.41 -0.75 -1.16
6955 || orf19.2954 || || || Protein of unknown function; Hap43-repressed gene; repressed by nitric oxide || 1 -0.14 -0.24 -1.21 -1.09 -0.99 -0.92 0.35 0.45 -0.23 -0.07 -0.56 -0.99 -1.01 -0.93 -0.82 -0.79
6956 || orf19.1872 || || || Plasma membrane protein; repressed by nitric oxide || 1 0.11 0.08 -0.76 -0.82 -0.56 -0.82 0.39 0.37 -0.20 0.26 -0.34 -0.41 -0.69 -0.39 -0.73 -0.50
6957 || orf19.7059 || || || Ortholog(s) have endoribonuclease activity, role in nuclear mRNA surveillance of mRNP export, transcription, DNA-templated and cytoplasm, nucleus localization || 1 -0.13 -0.27 -0.41 -0.46 -0.63 -1.19 0.16 0.02 -0.22 -0.53 -0.42 -0.45 -0.33 -0.20 -0.67 -0.11
6958 || orf19.5253 || || || Has domain(s) with predicted ATP binding, protein tyrosine kinase activity and role in protein phosphorylation || 1 0.38 0.32 -0.23 -0.44 -0.61 -1.23 0.17 -0.05 -0.11 -0.43 -1.05 -0.84 -0.63 -0.33 -0.93 -0.50
6959 || orf19.5139 || || || Ortholog of C. dubliniensis CD36 : Cd36_72800, Candida tropicalis MYA-3404 : CTRG_05211 and Candida albicans WO-1 : CAWG_05649 || 1 -0.09 -0.14 -0.58 -0.71 -0.99 -1.79 -0.02 0.09 -0.31 -0.49 -0.89 -1.19 -0.24 -0.23 -1.14 -0.64
6960 || orf19.3345 || SIZ1 || || Possible SUMO/Smt3 ligase; Rim101-repressed || 1 0.15 -0.03 -0.36 -0.58 -0.86 -1.32 -0.27 -0.11 -0.33 -0.45 -0.76 -1.29 0.03 -0.25 -0.98 -0.86
6961 || orf19.3579 || ATP4 || || Putative F0-ATP synthase subunit 4; macrophage/pseudohyphal-induced; present in exponential and stationary growth phases || 1 0.23 0.08 -0.77 -0.59 -1.23 -1.03 0.34 0.10 0.02 -0.09 -1.11 -1.23 0.12 0.07 -1.16 -1.02
6962 || orf19.782 || || || Ortholog(s) have serine hydrolase activity, triglyceride lipase activity, role in lipid homeostasis and lipid particle localization || 1 0.15 0.11 -0.44 -0.09 -0.95 -1.50 0.23 -0.05 -0.05 -0.19 -1.12 -1.04 0.10 -0.14 -0.20 -0.46
6963 || orf19.1377 || IPK2 || || Putative inositol polyphosphate multikinase; moderately induced at 42 deg || 1 0.27 0.12 -0.36 -0.35 -0.91 -1.26 0.24 0.05 -0.42 -0.09 -0.62 -0.77 -0.08 0.20 -0.26 -0.26
6964 || orf19.1376 || || || Ortholog(s) have SNAP receptor activity, phosphatidic acid binding activity || 1 -0.31 -0.30 -0.45 -0.21 -0.76 -1.02 -0.03 0.01 -0.70 0.27 -0.62 -0.47 -0.39 -0.01 -0.60 -0.45
6965 || orf19.7093 || HGT13 || || Predicted sugar transporter, involved in glycerol utilization; member of the major facilitator superfamily; 12 transmembrane; gene has intron; oxidative stress-induced via Cap1p; expressed in rich medium, 2% glucose || 1 -0.51 -0.39 -0.52 -0.61 -0.73 -1.43 -0.31 -0.29 -0.46 0.86 -0.57 -0.81 -0.54 -0.58 -0.70 -0.35
6966 || orf19.7093 || HGT13 || || Predicted sugar transporter, involved in glycerol utilization; member of the major facilitator superfamily; 12 transmembrane; gene has intron; oxidative stress-induced via Cap1p; expressed in rich medium, 2% glucose || 1 -0.68 -0.54 -0.28 -0.39 -1.20 -1.28 -0.76 -0.89 -0.36 0.87 -1.28 -0.85 -0.86 -0.47 -1.22 -0.80
6967 || orf19.815 || DCK1 || || Putative guanine nucleotide exchange factor; required for embedded filamentous growth; activates Rac1; has a DOCKER domain; similar to adjacent DCK2 and to S. cerevisiae Ylr422wp; regulated by Nrg1; Spider biofilm induced || 1 -0.25 -0.20 -0.55 -0.28 -1.13 -1.48 -0.34 -0.58 0.08 0.31 -0.80 -0.59 -0.49 -0.40 -0.48 -0.56
6968 || orf19.815 || DCK1 || || Putative guanine nucleotide exchange factor; required for embedded filamentous growth; activates Rac1; has a DOCKER domain; similar to adjacent DCK2 and to S. cerevisiae Ylr422wp; regulated by Nrg1; Spider biofilm induced || 1 -0.13 -0.21 -0.74 -0.44 -1.25 -1.55 -0.34 -0.47 0.06 0.34 -0.93 -0.64 -0.50 -0.52 -0.60 -0.56
6969 || orf19.6705 || || || Putative guanyl nucleotide exchange factor with Sec7 domain; required for normal filamentous growth; regulated by yeast-hyphal switch; filament induced; regulated by Nrg1, Tup1, Mob2, Hap43; mRNA binds She3; Spider biofilm induced || 1 -0.65 -0.69 -1.71 -0.48 -1.42 -1.91 -0.39 -0.75 -0.12 1.02 -0.80 -1.21 -0.38 -0.69 -1.21 -1.53
6970 || orf19.5919 || MEA1 || || Protein similar to A. nidulans MesA, which is involved in localization of actin cables; Hap43p-induced gene || 1 -0.64 -0.68 -1.02 -0.69 -0.94 -1.64 -0.42 -0.38 -0.39 0.64 -0.96 -0.70 0.05 -0.63 -0.52 -2.03
6971 || orf19.7056 || || || Putative protein of unknown function; transcript is upregulated in clinical isolates from HIV+ patients with oral candidiasis; regulated by Sef1, Sfu1, and Hap43 || 1 -1.14 -1.33 -1.58 -0.43 -0.87 -1.78 -0.19 -0.65 0.28 0.83 -1.68 -1.34 -2.14 -1.89 -1.70 -1.84
6972 || orf19.7056 || || || Putative protein of unknown function; transcript is upregulated in clinical isolates from HIV+ patients with oral candidiasis; regulated by Sef1, Sfu1, and Hap43 || 1 -1.04 -1.18 -0.93 0.19 -0.96 -1.37 0.21 -0.33 0.74 0.79 -2.04 -1.04 -1.87 -2.40 -2.01 -1.99
6973 || orf19.6385 || ACO1 || || Aconitase; induced in high iron; 2 upstream CCAAT motifs; amino acid starvation (3-AT), amphotericin B, phagocytosis, farnesol induced; Hap43, fluconazole-repressed; Gcn4-regulated; antigenic in infection; flow and Spider biofilm repressed || 1 -0.05 0.03 -0.11 0.22 -0.25 -0.53 0.36 0.23 0.21 0.67 -0.87 -0.55 -1.40 -0.80 -0.68 -0.83
6974 || orf19.6385 || ACO1 || || Aconitase; induced in high iron; 2 upstream CCAAT motifs; amino acid starvation (3-AT), amphotericin B, phagocytosis, farnesol induced; Hap43, fluconazole-repressed; Gcn4-regulated; antigenic in infection; flow and Spider biofilm repressed || 1 0.04 0.05 -0.28 0.04 -0.28 -0.63 0.26 0.26 0.30 0.49 -0.69 -0.86 -1.14 -1.22 -0.62 -1.23
6975 || orf19.2871 || SDH12 || || Succinate dehydrogenase; soluble protein in hyphae; macrophage-downregulated protein level; downregulated by Efg1p; repressed by nitric oxide; protein present in exponential and stationary growth phase yeast cultures; Hap43p-repressed gene || 1 -0.17 -0.28 -0.50 -0.32 -1.00 -0.89 0.20 0.13 0.34 0.45 -0.45 -0.53 -1.39 -1.21 -0.61 -1.15
6976 || orf19.2871 || SDH12 || || Succinate dehydrogenase; soluble protein in hyphae; macrophage-downregulated protein level; downregulated by Efg1p; repressed by nitric oxide; protein present in exponential and stationary growth phase yeast cultures; Hap43p-repressed gene || 1 -0.20 -0.15 -0.57 -0.33 -0.74 -0.71 0.43 0.31 0.28 0.54 -0.14 -0.27 -1.37 -0.90 -0.51 -0.97
6977 || orf19.1789.1 || LYS1 || || Saccharopine dehydrogenase (biosynthetic); enzyme of alpha-aminoadipate lysine biosynthesis pathway; functionally complements S. cerevisiae lys1 mutation; fungal-specific (no human or murine homolog) || 1 -0.03 -0.32 -0.17 0.30 -0.99 -0.87 0.48 0.42 0.49 -0.28 -0.47 -0.65 -0.83 -0.69 -0.59 -0.59
6978 || orf19.6178 || FBP1 || || Fructose-1,6-bisphosphatase; key gluconeogenesis enzyme; regulated by Efg1, Ssn6; induced by phagocytosis; effects switch from glycolysis to gluconeogenesis in macrophage; rat flow model biofilm induced; overlaps orf19.6179 || 1 -0.37 -0.41 0.16 0.14 -1.25 -0.91 0.30 0.19 0.27 0.23 -0.72 -0.38 -0.89 -0.15 -0.31 -0.99
6979 || orf19.6794 || FESUR1 || || Putative ubiquinone reductase; transcriptionally induced by interaction with macrophage; alkaline downregulated; repressed by nitric oxide; clade-associated gene expression; Hap43p-repressed gene || 1 0.18 -0.00 0.11 0.19 -1.26 -0.65 0.02 0.16 0.35 0.31 -0.92 -0.23 -0.88 -0.49 -0.18 -0.75
6980 || orf19.5750 || SHM2 || || Cytoplasmic serine hydroxymethyltransferase; complements glycine auxotrophy of S. cerevisiae shm1 shm2 gly1-1 mutant; antigenic; farnesol-upregulated in biofilm; stationary-phase enriched protein; rat catheter and Spider biofilm repressed || 1 0.07 -0.03 0.16 0.23 -0.81 -0.39 0.00 -0.02 0.20 -0.10 -0.63 -0.37 -0.87 0.24 -0.31 -0.29
6981 || orf19.3545 || || || Ortholog(s) have protein serine/threonine kinase activity, role in meiotic anaphase II, protein phosphorylation, septation initiation signaling cascade and cellular bud neck, cytoplasm, new mitotic spindle pole body, nucleus localization || 1 -0.31 -0.31 -0.07 0.02 -0.23 -0.56 -0.31 -0.43 -0.17 -0.47 -0.46 -0.06 -0.85 -0.26 -0.57 -0.38
6982 || orf19.4179 || || || Putative adhesin-like protein || 1 -0.25 -0.08 -0.23 -0.17 -0.58 -0.34 -0.15 0.14 -0.45 -0.13 -0.85 -0.41 -0.40
6983 || orf19.5692 || || || Ortholog(s) have ubiquitin-protein ligase activity, role in anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process, protein ubiquitination and anaphase-promoting complex localization || 1 -0.26 -0.19 -0.06 0.28 -0.92 -0.93 -0.41 -0.36 -0.03 0.03 -0.34 -0.65 -1.17 -0.75 -0.86 -0.05
6984 || orf19.5194.1 || || || Putative protein of unknown function; clade-associated gene expression || 1 0.03 0.00 -0.24 -0.23 -0.58 -0.59 -0.06 -0.06 0.25 0.12 -0.23 -0.23 -1.04 -0.37 -0.73 -0.32
6985 || orf19.5692 || || || Ortholog(s) have ubiquitin-protein ligase activity, role in anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process, protein ubiquitination and anaphase-promoting complex localization || 1 -0.14 -0.10 -0.29 -0.08 -0.28 -0.42 -0.33 -0.19 -0.17 0.30 -0.35 -0.23 -0.93 -0.63 -0.73 -0.24
6986 || orf19.1557 || || || Ortholog(s) have S-adenosylmethionine-dependent methyltransferase activity, role in protein methylation and cytosol, nucleus localization || 1 -0.04 -0.03 -0.48 -0.00 -0.27 -0.46 -0.32 -0.20 -0.07 -0.08 -0.53 -0.61 -1.16 -0.11 -1.14 -0.52
6987 || orf19.732 || || || Possible dehydrogenase; flow model biofilm induced; rat catheter biofilm induced; Spider biofilm induced || 1 -0.01 -0.03 0.26 0.11 -0.55 -0.38 -0.03 -0.49 0.18 -0.25 -0.63 -0.55 -1.08 -0.25 -0.86 -0.41
6988 || orf19.732 || || || Possible dehydrogenase; flow model biofilm induced; rat catheter biofilm induced; Spider biofilm induced || 1 -0.02 0.12 -0.34 -0.04 -1.01 -0.20 -0.13 -0.42 -0.02 -0.73 -1.03 -1.24 -1.15 -0.66 -1.14 -0.49
6989 || orf19.1815 || || || Ortholog of S. cerevisae/S. pombe Tif6; constituent of 66S pre-ribosomal particles; Spider biofilm induced || 1 -0.44 -0.37 -0.34 -0.40 -0.57 -0.09 0.05 -0.43 -0.10 0.40 -0.49 -0.56 -0.85 -0.34 -0.86 -0.53
6990 || orf19.7427 || || || Ortholog(s) have Golgi apparatus, fungal-type vacuole membrane localization || 1 -0.61 -0.74 -0.14 0.10 -1.23 -0.94 -0.59 -0.25 0.17 0.82 -0.70 -0.51 0.01 -0.18 -1.15 -0.54
6991 || orf19.2158 || NAG3 || || Putative MFS transporter; similar to Nag4; required for wild-type mouse virulence and cycloheximide resistance; in gene cluster that includes genes encoding enzymes of GlcNAc catabolism; Spider biofilm repressed || 1 -0.80 -0.85 -0.21 0.00 -1.32 -0.89 -0.24 -0.23 -0.35 0.24 -0.90 -1.02 -1.18 -0.05 -1.75 -1.36
6992 || orf19.2158 || NAG3 || || Putative MFS transporter; similar to Nag4; required for wild-type mouse virulence and cycloheximide resistance; in gene cluster that includes genes encoding enzymes of GlcNAc catabolism; Spider biofilm repressed || 1 -0.62 -0.63 0.11 0.38 -1.06 -0.84 0.07 0.20 0.18 0.60 -0.56 -0.75 -0.88 0.06 -1.28 -1.17
6993 || orf19.3239 || CTF18 || || Protein with a predicted role in sister chromatid cohesion; cell-cycle regulated periodic mRNA expression || 1 -0.32 -0.55 -0.06 0.19 -0.45 -0.77 0.15 0.58 0.19 0.76 -0.13 -0.62 -0.49 0.04 -1.24 -0.74
6994 || orf19.4242 || CST20 || || Protein kinase of Ste20p/p65PAK family, required for wild-type mating efficiency and virulence in a mouse model; Cst20p-Hst7p-Cek1p-Cph1p MAPK pathway regulates some hyphal growth; involved in Cdc42p growth regulation || 1 0.04 -0.25 0.16 0.35 -0.36 -0.86 0.12 0.25 -0.21 0.13 -0.31 -0.25 0.21 0.14 -0.42 -0.66
6995 || orf19.6343 || FEN1 || || Putative fatty acid elongase; predicted role in sphingolipid biosynthesis; possibly an essential gene, disruptants not obtained by UAU1 method; Spider and flow model biofilm induced || 1 -0.18 -0.04 0.13 0.49 -0.39 -1.55 -0.42 -0.42 -0.25 0.45 -0.46 -0.34 0.33 0.04 -0.44 -0.50
6996 || orf19.5244 || MCD4 || || Protein of major facilitator superfamily; has phosphodiesterase/nucleotide pyrophosphatase domain; similar to S. cerevisiae Mcd4p, which acts in GPI anchor biosynthesis; possibly an essential gene, disruptants not obtained by UAU1 method || 1 0.12 0.11 0.40 0.46 -0.42 -1.64 -0.16 -0.05 -0.16 0.44 -0.38 -0.69 0.17 0.55 -0.41 -0.42
6997 || orf19.2003 || HNM1 || || Putative choline/ethanolamine transporter; mutation confers hypersensitivity to toxic ergosterol analog; colony morphology-related gene regulation by Ssn6; clade-associated gene expression || 1 0.03 0.14 0.44 0.88 -0.55 -1.36 -0.18 -0.05 -0.72 0.55 -0.44 -1.07 0.11 0.46 -0.28 -0.48
6998 || orf19.2133 || LIP4 || || Secreted lipase, member of a differentially expressed lipase gene family with possible roles in nutrition and/or in creating an acidic microenvironment; expressed more strongly during mucosal infections than during systemic infections || 1 -0.51 -0.69 0.37 1.23 -1.31 -2.06 -0.31 0.04 -0.55 0.28 -1.69 -1.44 0.40 0.14 -0.87 -0.62
6999 || orf19.6781 || ZFU2 || || Zn(II)2Cys6 transcription factor; regulator of yeast form adherence; mutants display increased colonization of mouse kidneys; required for yeast cell adherence to silicone substrate; Spider biofilm induced || 1 0.16 -0.01 0.34 0.98 -2.61 -2.78 0.01 -0.76 -1.09 0.20 -2.23 -1.41 1.13 1.19 -0.12 -0.88
7000 || orf19.6781 || ZFU2 || || Zn(II)2Cys6 transcription factor; regulator of yeast form adherence; mutants display increased colonization of mouse kidneys; required for yeast cell adherence to silicone substrate; Spider biofilm induced || 1 0.14 0.03 0.44 0.97 -2.76 -3.84 -0.10 -0.77 -1.23 -0.06 -2.12 -1.62 1.59 1.15 -0.01 -0.84
7001 || orf19.1618 || GFA1 || || Glucosamine-6-phosphate synthase, homotetrameric enzyme of chitin/hexosamine biosynthesis; inhibited by UDP-GlcNAc, FMDP, N-acyl peptide, kanosamine-6-P; functional homolog of S. cerevisiae Gfa1p; Cagrowth-phase regulated; catalytic Cys || 1 0.31 0.31 0.58 0.71 -2.60 -2.33 -0.17 -0.31 -0.68 -0.14 -0.79 -1.08 0.77 0.79 -0.60 -0.29
7002 || orf19.1618 || GFA1 || || Glucosamine-6-phosphate synthase, homotetrameric enzyme of chitin/hexosamine biosynthesis; inhibited by UDP-GlcNAc, FMDP, N-acyl peptide, kanosamine-6-P; functional homolog of S. cerevisiae Gfa1p; Cagrowth-phase regulated; catalytic Cys || 1 0.17 0.05 0.49 0.60 -2.73 -2.44 -0.49 -0.78 -0.99 -0.43 -1.18 -1.10 0.49 0.78 -0.97 0.08
7003 || orf19.7456 || || || Protein of unknown function; flow model biofilm repressed || 1 0.31 0.13 0.46 0.37 -0.70 -0.93 -0.52 0.02 -0.15 0.41 -0.62 -0.58 -0.09 0.22 -0.07 0.07
7004 || orf19.1002 || || || Protein of unknown function; Hap43-repressed gene || 1 0.19 0.16 -0.09 0.02 -0.40 -0.49 -0.14 -0.58 -0.19 -0.46 -1.44 -0.61 -0.23 -0.41 -0.72 -0.07
7005 || orf19.5784 || AMO1 || || Putative peroxisomal copper amine oxidase || 1 0.37 0.33 0.85 0.87 -2.10 -1.05 0.15 -1.41 0.25 -1.43 -2.37 -0.56 0.12 -0.49 -1.65 0.55
7006 || orf19.5784 || AMO1 || || Putative peroxisomal copper amine oxidase || 1 0.40 0.52 0.59 0.81 -2.70 -1.33 0.38 -1.38 0.12 -1.62 -2.60 -0.77 0.77 -0.87 -1.57 -0.06
7007 || orf19.5784 || AMO1 || || Putative peroxisomal copper amine oxidase || 1 0.72 0.76 0.89 0.99 -2.05 -1.00 0.34 -1.22 0.40 -1.32 -1.99 -0.50 1.06 -0.76 -1.28 0.53
7008 || orf19.5784 || AMO1 || || Putative peroxisomal copper amine oxidase || 1 0.28 0.14 0.37 0.44 -1.02 -0.78 -0.04 -0.83 -0.32 -1.15 -1.41 -0.44 0.50 -0.74 -0.48 0.34
7009 || orf19.3986 || PPR1 || || Putative transcription factor with zinc cluster DNA-binding motif; has similarity to S. cerevisiae Ppr1p, which is a transcription factor involved in the regulation of uracil biosynthesis genes || 1 0.23 -0.04 0.38 -0.10 -0.79 -0.64 -0.07 -0.25 -0.13 -0.33 -0.88 -0.78 0.33 -0.41 -0.70 -0.34
7010 || orf19.5323 || MDH1-3 || || Predicted malate dehydrogenase; farnesol regulated; protein present in exponential and stationary growth phase yeast; Hap43p-repressed gene || 1 -0.01 -0.05 0.35 0.12 -0.54 -0.52 -0.39 -0.30 0.05 -0.61 -0.83 -0.34 -0.11 -0.25 -0.84 -0.01
7011 || orf19.4035 || PGA4 || || GPI-anchored cell surface protein; beta-1,3-glucanosyltransferase with similarity to the A. fumigatus GEL family; transcript induced in RHE model of oral candidiasis; fluconazol-induced || 1 0.07 0.13 0.35 0.13 -0.29 -0.50 -0.38 -0.31 -0.27 -0.41 -0.61 -0.15 0.17 -0.19 -0.67 -0.30
7012 || orf19.5754 || || || Putative membrane protein with a predicted role in zinc ion homeostasis; Hap43-induced; fluconazole-induced; rat catheter and Spider biofilm induced || 1 0.06 0.07 0.56 0.21 -0.25 -0.22 -0.47 -0.27 -0.28 -0.53 -0.66 -0.60 -0.26 0.51 -1.15 -0.19
7013 || orf19.3888.2 || || || Dubious open reading frame || 1 -0.22 -0.10 0.44 -0.05 -0.65 0.18 -0.71 -0.51 -0.87 -0.51 -0.29 -0.43 -0.52 0.13 -1.08 0.09
7014 || orf19.242 || SAP8 || || Secreted aspartyl protease; regulated by growth phase, temperature, white-opaque switch; highly expressed in opaque cells and upon deep epidermal invasion; greater expression in vaginal than oral infection; prominent role in biofilms || 1 -0.05 0.22 -0.10 0.48 -1.21 -0.68 -0.00 -0.58 -0.95 -1.03 -1.04 -0.51 0.19 -1.07 0.23
7015 || orf19.1653 || || || Has domain(s) with predicted integral to membrane localization || 1 -0.09 0.06 0.30 0.65 -1.16 -0.29 -1.13 -0.52 -0.64 -0.71 -0.41 -1.19 -0.85 -0.12 -1.14 -0.12
7016 || orf19.1653 || || || Has domain(s) with predicted integral to membrane localization || 1 0.28 0.21 0.66 0.81 -0.99 -0.11 -0.96 -0.28 -0.59 -0.66 -0.32 -0.98 -0.89 0.09 -0.91 0.35
7017 || orf19.1653 || || || Has domain(s) with predicted integral to membrane localization || 1 0.40 0.27 0.77 0.92 -0.69 0.01 -0.71 -0.00 -0.51 -0.56 -0.29 -0.75 -0.62 -0.08 -0.97 0.50
7018 || orf19.1743 || ACS1 || || Acetyl-CoA synthetase; induced by human neutrophils; fluconazole-repressed; regulated by Nrg1/Mig1; colony morphology-related gene regulation by Ssn6; only in stationary phase cultures; rat catheter biofilm repressed, Spider biofilm induced || 1 0.29 0.34 0.22 0.59 -0.71 -0.31 -0.04 -0.01 -0.34 -0.29 -0.27 -0.34 -0.59 -0.10 -1.07 0.06
7019 || orf19.6305 || || || Hydroxytrimethyllysine aldolase, the second enzyme in the carnitine biosynthesis pathway; rat catheter biofilm repressed || 1 0.17 0.16 0.40 0.65 -0.75 -0.45 0.02 -0.05 -0.04 -0.64 -0.39 0.01 -0.54 -0.24 -0.66 -0.16
7020 || orf19.3318 || || || Ortholog(s) have cytoplasm localization || 1 0.08 0.07 0.41 0.34 -0.48 -0.44 -0.26 -0.32 0.42 -0.04 -1.00 0.10 -0.76 0.03 -0.60 -0.07
7021 || orf19.7563 || BET2 || || Putative Type II geranylgeranyltransferase beta subunit; transcript regulated by Mig1 || 1 0.15 -0.06 0.38 0.26 -0.79 -0.45 -0.50 -0.44 0.19 0.14 -0.51 -0.02 -0.61 -0.41 -0.62 -0.33
7022 || orf19.2784 || || || Ortholog of C. dubliniensis CD36 : Cd36_07090, Candida tenuis NRRL Y-1498 : cten_CGOB_00237, Debaryomyces hansenii CBS767 : DEHA2F25542g and Pichia stipitis Pignal : psti_CGOB_00186 || 1 0.03 0.20 0.71 0.38 -1.40 -0.78 -0.95 -0.89 0.24 0.28 -1.79 0.12 -0.49 -0.41 -1.53 -0.25
7023 || orf19.2878 || PGA15 || || Putative GPI-anchored protein || 1 0.30 0.37 0.38 0.39 -0.91 -0.44 -0.47 -0.53 0.01 0.14 -0.75 -0.29 -0.57 -0.42 -0.83 0.25
7024 || orf19.5542 || SAP6 || || Secreted aspartyl protease; expressed during hyphal growth, oral carriage, infection; sap4,5,6 triple mutant defective in protein utilization as N source; virulence role affecte by URA3; N-glycosylated; rat catheter biofilm induced || 1 1.06 0.72 0.27 0.29 -1.51 -1.30 -1.09 -1.18 -0.31 0.09 -2.27 -0.39 -1.48 0.31 -1.60 0.10
7025 || orf19.5716 || SAP4 || || Secreted aspartyl proteinase; sap4,5,6 mutant defective in protein utilization for nitrogen; virulence role complicated by URA3 effects; expressed during mucosal and systemic infections; N-glycosylated; rat catheter, Spider biofilm induced || 1 1.11 1.06 0.28 0.35 -1.88 -0.82 -1.30 -1.40 -0.44 -0.64 -1.66 -0.39 -1.48 0.15 -1.40 -0.10
7026 || orf19.345 || || || Succinate semialdehyde dehydrogenase; for utilization of gamma-aminobutyrate (GABA) as a nitrogen source; part of 4-aminobutyrate and glutamate degradation pathways; rat catheter biofilm induced || 1 0.23 0.51 0.69 0.31 -1.09 -0.31 -1.15 -1.08 -0.47 -0.18 -1.35 -0.36 -1.10 0.21 -1.27 0.16
7027 || orf19.7661 || HMI1 || || ATP-dependent 3' - 5' helicase involved in maintenance of mitochondrial DNA; ortholog of S. cerevisiae Hmi1; rat catheter biofilm repressed || 1 0.58 0.30 0.66 0.33 -0.73 -0.44 -0.69 -1.21 -0.35 -0.75 -1.54 -0.78 -1.41 -0.63 -0.82 0.05
7028 || orf19.1639 || || || Has domain(s) with predicted oxidoreductase activity and role in oxidation-reduction process || 1 0.73 0.44 0.27 1.06 -1.21 -0.80 -1.04 -1.38 -0.85 -1.14 -1.53 -0.56 -1.03 0.02 -0.62 -0.10
7029 || orf19.2082 || SAP30 || || Aspartic-type endopeptidase; involved in degradation of alpha pheromone; functional equivalent of S. cerevisiae Bar1; a-cell specific; induced by alpha pheromone || 1 0.90 0.76 0.58 0.13 -1.23 -0.32 -0.88 -1.52 -0.23 0.61 -0.65 -0.68 -1.41 -0.55 -1.45 -0.10
7030 || orf19.155 || URE2 || || Functional homolog of S. cerevisiae Ure2p, which is a regulator of nitrogen utilization, and which also has an infectious prion form called [URE3]; forms [URE3] prion when expressed in S. cerevisiae || 1 0.21 0.03 0.15 0.32 -0.53 -0.22 -0.39 -0.61 -0.34 0.35 -0.84 -0.05 -0.44 -0.39 -0.41 -0.09
7031 || orf19.2583 || PTR2 || || Oligopeptide transporter involved in uptake of di-/tripeptides; highly induced during chlamydospore formation in both C. albicans and C. dubliniensis || 1 -0.19 -0.09 0.50 1.25 -0.94 -0.03 -0.46 -1.68 -0.37 0.15 -1.88 -0.89 -0.95 -0.92 -1.27
7032 || orf19.6879 || || || Ortholog(s) have tRNA-intron endonuclease activity, role in tRNA-type intron splice site recognition and cleavage and mitochondrial outer membrane, tRNA-intron endonuclease complex localization || 1 -0.04 -0.26 0.34 0.51 -0.54 -0.15 -0.22 -0.61 -0.43 0.05 -0.44 -0.13 -0.36 -0.11 -0.46 -0.19
7033 || orf19.3374 || ECE1 || || Hypha-specific protein; regulated by Rfg1, Nrg1, Tup1, Cph1, Efg1, Hog1, farnesol, phagocytosis; fluconazole-induced; rat catheter and Spider biofilm induced; flow model biofilm repressed; Bcr1-repressed in RPMI a/a biofilms || 1 0.31 -0.23 0.09 1.26 -2.01 -1.44 -0.81 -1.08 -0.94 0.61 -1.92 -0.18 -0.58 0.27 -1.71 0.30
7034 || orf19.6310 || || || Has domain(s) with predicted myosin binding activity || 1 0.11 0.20 0.54 0.75 -0.92 -0.78 -0.56 -0.77 -0.11 0.40 -1.01 -0.27 0.18 0.17 -1.06 0.32
7035 || orf19.6879 || || || Ortholog(s) have tRNA-intron endonuclease activity, role in tRNA-type intron splice site recognition and cleavage and mitochondrial outer membrane, tRNA-intron endonuclease complex localization || 1 0.05 0.01 0.40 0.47 -0.49 0.03 -0.11 -0.33 -0.31 0.11 -0.35 -0.06 -0.03 0.15 -0.35 0.13
7036 || orf19.7151 || || || Ortholog of Candida albicans WO-1 : CAWG_05751 || 1 0.50 0.88 1.52 1.78 -2.17 -0.68 -1.36 -0.07 -1.62 0.39 -1.49 -1.13 0.09
7037 || orf19.4804 || LIP2 || || Secreted lipase; member of a differentially expressed lipase gene family; expressed in alimentary tract, but not oral tissue, during mouse oral infection; may have a role in nutrition and/or in creating an acidic microenvironment || 1 0.60 0.57 0.74 2.48 -2.17 -1.25 -1.28 -0.89 -2.05 -0.15 -1.30 -1.20 -2.10 0.62
7038 || orf19.7606 || || || Ortholog of C. dubliniensis CD36 : Cd36_35262, Candida tropicalis MYA-3404 : CTRG_05848 and Candida albicans WO-1 : CAWG_02290 || 1 0.50 0.33 0.68 1.13 -1.03 -0.26 -0.40 -0.29 -0.14 -0.15 -0.57 -0.11 -0.14 -0.09 -0.30 0.22
7039 || orf19.2082 || SAP30 || || Aspartic-type endopeptidase; involved in degradation of alpha pheromone; functional equivalent of S. cerevisiae Bar1; a-cell specific; induced by alpha pheromone || 1 1.21 1.33 1.37 0.40 -1.61 -1.64 -0.40 -1.32 -1.03 0.29 -1.35 -0.60 -0.44 -0.65 -2.17 0.21
7040 || orf19.7151 || || || Ortholog of Candida albicans WO-1 : CAWG_05751 || 1 0.82 0.71 0.93 0.67 -0.94 -0.51 -0.28 0.14 -0.27 -0.47 -0.02 -0.55 0.26 -0.87 0.47
7041 || orf19.351 || || || Ortholog of S. cerevisiae : YPR153W, C. glabrata CBS138 : CAGL0L08382g, C. dubliniensis CD36 : Cd36_83540, C. parapsilosis CDC317 : CPAR2_404520 and Candida tenuis NRRL Y-1498 : CANTEDRAFT_115795 || 1 0.38 0.37 0.67 0.54 -0.16 -0.28 -0.47 -0.57 0.12 -0.28 -0.55 -0.40 -0.54 0.33 -0.31 0.31
7042 || orf19.5216 || || || Has domain(s) with predicted acyl-CoA hydrolase activity and role in acyl-CoA metabolic process || 1 0.56 0.92 1.50 1.90 -1.10 -0.65 -1.00 -1.11 -2.06 -0.25 -0.70 -0.68 -0.26 -0.39 -0.66 -0.38
7043 || orf19.3458 || || || Ortholog(s) have role in late endosome to vacuole transport via multivesicular body sorting pathway, protein targeting to vacuole and Golgi apparatus, Vps55/Vps68 complex, fungal-type vacuole membrane, mitochondrion localization || 1 -0.13 -0.27 0.44 0.43 -0.33 -0.23 -0.36 -0.36 -0.23 -0.25 -0.33 0.07 -0.34 -0.11 0.08 -0.24
7044 || orf19.5121 || OPT5 || || Oligopeptide transporter; fungal-specific (no human or murine homolog); induced by BSA, but not by tetrapeptide or pentapeptide || 1 -0.00 -0.21 0.37 1.07 -0.51 0.12 -0.40 -0.38 -0.19 -0.16 -0.51 0.23 -0.41 -0.11 -0.41 -0.29
7045 || orf19.344 || || || Protein of unknown function; upregulated by fluphenazine treatment or in an azole-resistant strain that overexpresses CDR1 and CDR2; transcript possibly regulated by Tac1 || 1 -0.10 0.04 0.86 1.28 -0.39 -0.11 -0.61 -0.52 -0.26 -0.37 -0.73 -0.04 -0.44 -0.17 -0.93 -0.38
7046 || orf19.5022 || || || Ortholog(s) have inorganic cation transmembrane transporter activity and role in cellular cobalt ion homeostasis, cellular manganese ion homeostasis, cobalt ion transport, manganese ion transport || 1 -0.07 -0.03 0.83 0.92 -0.50 -0.02 -0.71 -0.47 -0.52 -0.46 -0.94 -0.34 -0.41 -0.32 -0.26 -0.28
7047 || orf19.832 || GPI13 || || Major facilitator superfamily protein; has phosphodiesterase/nucleotide pyrophosphatase domain; similar to S. cerevisiae Gpi13p, which acts in GPI anchor biosynthesis; Hap43p-induced gene || 1 0.20 0.05 0.42 0.63 -0.19 -0.17 -0.51 -0.37 -0.57 0.15 -0.58 0.03 -0.20 -0.07 -0.59 -0.40
7048 || orf19.4822 || LIP10 || || Secreted lipase, member of a lipase gene family whose members are expressed differentially in response to carbon source and during infection; may have a role in nutrition and/or in creating an acidic microenvironment || 1 -0.13 0.04 1.08 0.59 -0.00 -0.16 -0.44 -0.49 -0.14 -0.40 -0.67 -0.34 -0.17 -0.04 -0.76 -0.10
7049 || orf19.2444 || CHS7 || || Protein required for wild-type chitin synthase III activity; similar to (but not functional homolog of) S. cerevisiae Chs7p, which effects ER export of Chs3p; induced cyr1 mutant hyphae and ras1 yeast-form cells; Spider biofilm induced || 1 -0.23 -0.12 0.54 0.33 -0.22 -0.24 -0.63 -0.56 -0.17 -0.29 -0.68 -0.01 0.20 -0.25 -0.02 -0.40
7050 || orf19.644 || HGT9 || || Putative glucose transporter of the major facilitator superfamily; the C. albicans glucose transporter family comprises 20 members; 12 probable membrane-spanning segments; induced at low (0.2%, compared to 2%) glucose in rich media; intron || 1 -0.19 -0.27 0.48 0.78 -0.35 -0.16 -0.49 -0.53 -0.19 -0.54 -0.57 -0.06 0.30 -0.38 -0.29 -0.43
7051 || orf19.7379 || FAA2 || || Putative acyl CoA synthetase; expression regulated upon white-opaque switch; rat catheter biofilm induced; Spider biofilm induced || 1 -0.62 -0.61 0.49 0.65 -0.78 -0.50 -0.18 -0.39 -0.34 -0.67 -1.15 -0.34 0.21 -0.27 -0.36 -0.66
7052 || orf19.3544 || || || Putative protein of unknown function; Hap43p-repressed gene || 1 -0.17 -0.38 1.16 1.07 -1.22 -0.43 -0.67 -0.51 0.25 -0.84 -1.24 -0.57 -0.22 -0.27 -0.27 -0.37
7053 || orf19.3544 || || || Putative protein of unknown function; Hap43p-repressed gene || 1 -0.15 -0.07 1.14 1.09 -1.39 -0.32 -0.76 -0.49 -0.02 -1.31 -1.35 -0.83 0.14 -0.77 -0.32 -0.68
7054 || orf19.3544 || || || Putative protein of unknown function; Hap43p-repressed gene || 1 -0.00 -0.02 1.35 1.34 -1.10 -0.37 -0.30 -0.27 -0.11 -1.36 -1.04 -0.77 0.05 -0.44 0.09 -0.53
7055 || orf19.3544 || || || Putative protein of unknown function; Hap43p-repressed gene || 1 0.09 0.18 1.12 1.25 -1.17 -0.20 -0.33 -0.21 -0.03 -1.05 -0.98 -0.54 0.05 -0.34 0.19 -0.40
7056 || orf19.3749 || IFC3 || || Oligopeptide transporter; transcript induced by macrophage phagocytosis, BSA or peptides; fluconazole-induced; induced by Rim101 at pH 8; virulence-group-correlated expression; Hap43-repressed; Spider biofilm induced || 1 -0.01 -0.13 0.83 0.94 -0.79 -0.59 -0.08 -0.49 -0.07 -0.24 -1.09 -0.43 -0.35 -0.82 0.39 -0.37
7057 || orf19.3746 || IFC1 || || Oligopeptide transporter; induced upon phagocytosis by macrophage; macrophage/pseudohyphal-repressed after 16h; fluconazole-induced; virulence-group-correlated expression; Hap43-repressed || 1 -0.06 0.02 1.00 1.24 -0.64 -1.06 -0.23 -0.36 -0.29 -0.39 -1.10 -0.14 -0.21 -0.71 -0.22 -0.18
7058 || orf19.6998 || GTT1 || || Putative glutathione S-transferase; downregulated upon adherence to polystyrene; regulated upon white-opaque switching; induced in the presence of human neutrophils; oxidative stress-induced via Cap1p; regulated by Gcn2p, Gcn4p || 1 -0.07 0.08 1.06 1.50 -0.05 -0.48 -0.31 -0.07 -0.09 -0.23 -0.89 -0.42 -0.32 -0.71 -0.31 -0.23
7059 || orf19.3773 || CDL1 || || Putative RNAse III, ortholog of S. cerevisiae RNT1; merged with orf19.3772 in Assembly 21 || 1 0.12 -0.04 0.53 0.73 -0.11 -0.33 -0.14 0.01 -0.25 -0.38 -0.35 0.09 -0.18 -0.33 -0.05 -0.08
7060 || orf19.5775 || || || Predicted ORF overlapping the Major Repeat Sequence on chromosome 6; member of a family encoded by FGR6-related genes in the RB2 repeat sequence; rat catheter biofilm repressed || 1 -0.09 -0.12 0.69 0.72 -0.17 -0.75 -0.31 0.02 -0.22 -0.02 -0.44 -0.37 0.07 -0.36 -0.07 -0.01
7061 || orf19.3120 || || || PDR-subfamily ABC transporter (half-size); similar to WHITE subfamily proteins; repressed by fluphenazine treatment or in an azole-resistant strain that overexpresses CDR1 and CDR2; induced by nitric oxide; rat catheter biofilm induced || 1 -0.50 0.25 0.65 0.79 -0.80 -0.49 0.02 -0.23 -0.04 -0.49 -1.16 -0.61 -0.51 -0.38 -0.46 -0.43
7062 || orf19.242 || SAP8 || || Secreted aspartyl protease; regulated by growth phase, temperature, white-opaque switch; highly expressed in opaque cells and upon deep epidermal invasion; greater expression in vaginal than oral infection; prominent role in biofilms || 1 -0.21 0.23 0.93 0.92 -0.48 -0.37 -0.11 -0.15 0.25 -0.20 -0.56 -0.19 -0.06 0.34 -0.14 -0.51
7063 || orf19.651 || LYP1 || || Putative permease; amphotericin B induced; flucytosine repressed; possibly an essential gene, disruptants not obtained by UAU1 method || 1 0.15 -0.11 0.44 0.57 -0.08 -0.25 -0.17 0.00 0.26 -0.23 -0.31 0.02 -0.06 0.10 -0.07 -0.20
7064 || orf19.5345 || || || Putative ubiquitin-like polyubiquitin-binding protein; induced by nitric oxide independent of Yhb1; Spider biofilm repressed || 1 0.28 0.32 0.52 0.63 -0.16 -0.33 -0.06 0.19 -0.29 -0.08 -0.17 -0.37 -0.32 -0.34 0.15 -0.10
7065 || orf19.5345 || || || Putative ubiquitin-like polyubiquitin-binding protein; induced by nitric oxide independent of Yhb1; Spider biofilm repressed || 1 0.19 0.06 0.46 0.57 -0.44 -0.54 -0.22 0.07 -0.50 -0.23 -0.41 -0.37 -0.74 -0.52 -0.01 -0.14
7066 || orf19.3376 || || || Ortholog of Candida albicans WO-1 : CAWG_03459 || 1 0.42 -0.03 1.19 1.47 -1.18 -1.32 -0.88 -1.11 -0.70 -0.54 -0.55 -1.50 -1.12 -0.93 -0.54 0.53
7067 || orf19.3376 || || || Ortholog of Candida albicans WO-1 : CAWG_03459 || 1 0.71 0.73 1.40 1.82 -1.49 -0.90 -0.21 -0.74 -0.43 -1.49 -0.95 -2.75 -0.43 -2.26 -0.42 0.05
7068 || orf19.2496 || ATO2 || || Putative fungal-specific transmembrane protein; fluconazole repressed, Hap43-repressed; flow model biofilm induced; Spider biofilm induced || 1 0.07 0.18 0.72 1.23 -0.14 -0.25 -0.48 -0.42 -0.32 0.05 -0.47 -0.61 0.01 -1.19 -0.28 0.18
7069 || orf19.6520 || || || Putative allantoate permease; fungal-specific (no human or murine homolog) || 1 -0.10 0.14 0.03 2.12 -0.44 0.17 -0.54 -0.86 -0.33 -0.26 -0.69 -1.47 -0.55 -1.23 0.07 0.04
7070 || orf19.3782 || || || Predicted membrane transporter; member of the peptide-acetyl-coA transporter (PAT) family, major facilitator superfamily (MFS); induced by alpha pheromone in Spider medium || 1 0.10 0.08 0.60 0.64 -0.22 -0.24 -0.16 -0.07 0.12 0.48 -0.64 -0.07 0.04 -0.16 0.01 -0.14
7071 || orf19.4121 || || || Predicted thioesterase/thiol ester dehydrase-isomerase; Spider biofilm induced || 1 0.59 0.65 1.15 1.88 -0.51 -0.64 -0.21 0.53 -0.27 1.60 -1.78 -1.17 -0.20 -0.20 -0.02 -0.63
7072 || orf19.5142 || DFR1 || || Trimethoprim resistant dihydrofolate reductase (DHFR), reduces 7,8-dihydrofolate to 5,4,7,8-tetrahydrofolate; binds NADPH; target of drugs that selectively inhibit the fungal enzyme rather than the human enzyme || 1 0.09 0.18 0.90 1.04 -0.34 -0.33 0.13 0.25 0.24 0.74 -0.37 -0.43 0.02 0.24 -0.04 -0.26
7073 || orf19.2133 || LIP4 || || Secreted lipase, member of a differentially expressed lipase gene family with possible roles in nutrition and/or in creating an acidic microenvironment; expressed more strongly during mucosal infections than during systemic infections || 1 0.13 0.29 1.23 1.96 -0.49 -0.70 -0.38 0.52 -0.51 0.55 -0.97 -2.13 -0.40 -0.33 -0.04 -0.93
7074 || orf19.4933 || FAD3 || || Omega-3 fatty acid desaturase; production of alpha-linolenic acid, a major component of membranes; caspofungin induced; Plc1-regulated; colony morphology-related gene regulation by Ssn6; Spider biofilm induced, flow model biofilm repressed || 1 0.25 0.22 0.76 1.13 -0.50 -0.75 -0.14 -0.09 -0.51 0.61 -0.82 -1.22 -0.02 0.37 -0.52 -1.01
7075 || orf19.4121 || || || Predicted thioesterase/thiol ester dehydrase-isomerase; Spider biofilm induced || 1 0.29 0.36 0.67 1.88 -0.78 -1.50 -0.71 -0.04 -1.21 1.21 -1.04 -1.33 0.08 -0.78 -0.28 -2.02
7076 || orf19.6126 || KGD2 || || Putative dihydrolipoamide S-succinyltransferase; induced in high iron; Hap43-repressed; Spider biofilm repressed || 1 0.31 0.42 0.46 0.52 -0.23 -0.11 -0.02 0.09 -0.39 0.62 -1.20 -0.99 -0.54 -0.03 -0.26 -0.60
7077 || orf19.2646 || ZCF13 || || Predicted Zn(II)2Cys6 transcription factor; similar to but not the true ortholog of S. cerevisiae Hap1; mutants display decreased colonization of mouse kidneys || 1 0.08 0.06 0.38 0.59 0.06 -0.36 0.04 0.34 -0.10 -0.25 -0.85 -0.49 -0.26 -0.08 0.03 -0.52
7078 || orf19.2646 || ZCF13 || || Predicted Zn(II)2Cys6 transcription factor; similar to but not the true ortholog of S. cerevisiae Hap1; mutants display decreased colonization of mouse kidneys || 1 -0.25 -0.35 0.16 0.45 -0.07 -0.31 -0.22 -0.07 -0.22 -0.05 -0.85 -0.49 -0.40 0.17 0.00 -0.71
7079 || orf19.4798 || || || Ortholog(s) have role in establishment of protein localization to plasma membrane and mitochondrion, plasma membrane localization || 1 -0.10 -0.30 0.01 0.60 -0.12 -0.52 0.11 0.01 -0.08 0.21 -0.56 -0.22 -0.31 0.02 -0.20 -0.35
7080 || orf19.2673 || || || Ortholog(s) have role in DNA repair and Smc5-Smc6 complex, cytoplasm, nucleus localization || 1 0.14 -0.11 0.21 0.43 -0.13 -0.34 -0.09 0.40 -0.27 0.78 -0.38 -0.22 -0.21 -0.14 -0.61 -0.45
7081 || orf19.3916 || || || Ortholog of C. dubliniensis CD36 : Cd36_53980, C. parapsilosis CDC317 : CPAR2_100980, Candida tenuis NRRL Y-1498 : CANTEDRAFT_116966 and Debaryomyces hansenii CBS767 : DEHA2G19822g || 1 0.53 0.27 0.21 0.76 0.37 -0.83 -0.25 0.23 -0.10 0.83 -0.64 -0.35 0.31 0.23 -0.65 -0.74
7082 || orf19.3916 || || || Ortholog of C. dubliniensis CD36 : Cd36_53980, C. parapsilosis CDC317 : CPAR2_100980, Candida tenuis NRRL Y-1498 : CANTEDRAFT_116966 and Debaryomyces hansenii CBS767 : DEHA2G19822g || 1 0.15 0.20 0.01 0.23 0.15 -0.46 -0.18 -0.10 -0.36 0.50 -0.58 0.00 0.17 -0.09 -0.60 -0.56
7083 || orf19.107 || || || DEAH-box ATP-dependent RNA helicase, required for 18S rRNA synthesis; rat catheter biofilm induced || 1 0.54 0.75 0.34 0.45 -0.28 0.48 -0.61 -0.83 -0.26 0.69 -0.82 -0.49 -0.06 0.24 -0.73 -0.36
7084 || orf19.7354 || LAC1 || || Ceramide synthase; required for biosynthesis of ceramides with C18:0 fatty acids, which serve as precursors for glucosylsphingolipids; caspofungin induced || 1 0.25 0.34 0.47 0.79 -0.07 -0.08 -0.81 -0.69 -0.01 0.78 -0.55 0.23 -0.04 -0.33 -1.07 -0.48
7085 || orf19.7354 || LAC1 || || Ceramide synthase; required for biosynthesis of ceramides with C18:0 fatty acids, which serve as precursors for glucosylsphingolipids; caspofungin induced || 1 0.45 0.49 0.51 0.65 0.05 -0.15 -0.72 -0.78 -0.19 0.68 -0.88 -0.05 -0.06 -0.51 -1.37 -0.77
7086 || orf19.7354 || LAC1 || || Ceramide synthase; required for biosynthesis of ceramides with C18:0 fatty acids, which serve as precursors for glucosylsphingolipids; caspofungin induced || 1 0.42 0.51 0.37 0.50 -0.17 -0.11 -0.84 -0.84 -0.15 0.71 -0.98 0.01 0.17 -0.04 -1.37 -1.27
7087 || orf19.7354 || LAC1 || || Ceramide synthase; required for biosynthesis of ceramides with C18:0 fatty acids, which serve as precursors for glucosylsphingolipids; caspofungin induced || 1 0.49 0.23 0.46 0.83 -0.56 0.02 -0.25 -0.43 -0.12 0.61 -0.65 -0.01 -0.07 -0.32 -0.89 -0.88
7088 || orf19.3769 || || || Ortholog(s) have zinc ion transmembrane transporter activity, role in zinc ion transport and endoplasmic reticulum localization || 1 0.25 0.24 0.35 0.62 -0.02 0.03 -0.22 -0.23 0.43 0.35 -0.42 0.04 -0.16 -0.15 -0.75 -0.69
7089 || orf19.832 || GPI13 || || Major facilitator superfamily protein; has phosphodiesterase/nucleotide pyrophosphatase domain; similar to S. cerevisiae Gpi13p, which acts in GPI anchor biosynthesis; Hap43p-induced gene || 1 0.16 0.35 0.57 0.81 0.10 -0.08 -0.37 -0.28 0.20 0.33 -0.70 -0.07 0.22 0.03 -0.79 -0.62
7090 || orf19.4240 || || || Ortholog(s) have role in GPI anchor biosynthetic process, cellular manganese ion homeostasis and endoplasmic reticulum, fungal-type vacuole membrane localization || 1 0.05 -0.04 0.02 0.31 -0.00 -0.22 -0.43 -0.35 0.05 0.26 -0.70 -0.44 -0.03 0.31 -0.46 -0.92
7091 || orf19.3255 || TEN1 || || Protein involved in telomere maintenance; forms a complex with Stn1; transcription is regulated upon yeast-hypha switch; Spider biofilm induced || 1 0.06 -0.17 0.12 0.40 -0.07 -0.05 -0.48 -0.23 -0.26 0.16 -0.56 -0.12 -0.14 0.18 -0.54 -0.61
7092 || orf19.2198 || FLC3 || || Protein involved in heme uptake; putative FAD transporter, similar to S. cerevisiae Flc3p || 1 -0.19 -0.03 0.07 0.40 -0.40 -0.67 -0.67 -0.52 -0.15 0.27 -0.46 -0.21 0.07 0.40 -0.55 -0.40
7093 || orf19.1720 || || || Ortholog(s) have role in mitotic recombination || 1 0.27 0.55 0.13 0.41 -0.07 -0.92 -0.81 -0.57 -0.38 0.75 -0.21 -0.51 -0.08 -0.33 -0.77 -0.99
7094 || orf19.6291 || || || Ortholog(s) have DNA binding, DNA-dependent ATPase activity, chromatin binding activity || 1 0.36 0.16 0.24 0.56 -0.21 -0.05 -0.46 0.07 -0.48 0.86 -0.30 -0.72 -0.47 -0.08 -0.85 -1.01
7095 || orf19.2575 || || || Putative S-adenosylmethionine-dependent methyltransferase; Hap43p-induced gene || 1 0.27 0.24 0.48 0.48 -0.47 0.26 -0.39 -0.09 -0.29 0.85 -0.73 -1.01 -0.48 -0.45 -0.57 -1.13
7096 || orf19.107 || || || DEAH-box ATP-dependent RNA helicase, required for 18S rRNA synthesis; rat catheter biofilm induced || 1 0.35 0.53 0.20 -0.03 0.02 0.28 -0.39 -0.48 -0.76 0.99 -1.04 -1.01 -0.03 -0.15 -0.68 -0.78
7097 || orf19.4120 || LAS1 || || Putative bud formation and morphogenesis protein; mutation confers hypersensitivity to 5-fluorocytosine (5-FC), 5-fluorouracil (5-FU); macrophage-induced; Spider biofilm induced || 1 0.10 0.08 0.59 0.12 -0.20 0.41 -0.71 -0.49 -0.31 0.45 -0.41 -0.32 -0.33 -0.48 -0.29 -0.44
7098 || orf19.939 || NAM7 || || Putative role in nonsense-mediated mRNA decay; similar to S. cerevisiae Nam7p; gene induced by ciclopirox olamine treatment || 1 -0.02 0.03 0.36 0.15 -0.17 0.03 -0.49 -0.32 -0.41 0.20 -0.50 -0.36 -0.16 -0.42 -0.54 -0.69
7099 || orf19.7384 || NOG1 || || Putative GTPase; mutation confers hypersensitivity to 5-fluorocytosine (5-FC), 5-fluorouracil (5-FU), and tubercidin (7-deazaadenosine); repressed by prostaglandins; Hap43-induced || 1 -0.33 -0.20 0.20 0.44 -0.44 0.31 -0.61 -0.57 -0.70 0.35 -0.72 -0.84 -0.40 -0.72 -0.26 -0.53
7100 || orf19.3151 || || || Has domain(s) with predicted catalytic activity, coenzyme binding activity and role in cellular metabolic process || 1 0.26 0.17 -0.08 0.06 -0.86 -1.09 -0.38 -0.13 -0.67 0.24 -1.14 -0.47 -1.03 0.23 -0.24 -0.32
7101 || orf19.4516 || || || Ortholog(s) have tetrahydrofolylpolyglutamate synthase activity, role in one-carbon metabolic process, regulation of DNA methylation and cytosol, mitochondrion, nucleus localization || 1 0.28 0.21 -0.12 0.12 -0.47 -0.56 -0.20 0.00 -0.09 0.25 -0.28 -0.20 -0.43 0.25 -0.43 -0.23
7102 || orf19.5345 || || || Putative ubiquitin-like polyubiquitin-binding protein; induced by nitric oxide independent of Yhb1; Spider biofilm repressed || 1 0.07 0.17 0.18 0.29 -0.48 -0.63 -0.24 0.22 -0.06 0.25 -0.35 -0.34 -0.40 -0.00 -0.20 -0.26
7103 || orf19.3151 || || || Has domain(s) with predicted catalytic activity, coenzyme binding activity and role in cellular metabolic process || 1 0.27 0.34 0.03 -0.21 -0.49 -1.05 -0.19 0.17 -0.23 0.65 -0.57 -0.17 -0.11 0.15 -0.16 -0.27
7104 || orf19.3738 || PGA22 || || Putative GPI-anchored protein; adhesin-like protein || 1 0.16 0.44 0.14 -0.44 -0.28 -1.17 -0.10 -0.13 -0.19 0.28 -0.70 -0.19 0.31
7105 || orf19.1824 || PGA50 || || Putative GPI-anchored protein; adhesin-like protein || 1 -0.02 -0.10 -0.75 0.41 -0.33 -1.22 0.01 0.14 0.16 0.19 -0.99 -1.43 -1.01 0.51 -0.61 -0.49
7106 || orf19.7411 || OAC1 || || Putative mitochondrial inner membrane transporter; rat catheter biofilm induced || 1 -0.23 -0.21 0.37 0.30 -1.03 -0.58 -0.03 -0.85 -0.06 1.00 -1.04 -0.04 -0.29 0.04 -0.42 -0.89
7107 || orf19.2151 || NAG6 || || Protein required for wild-type mouse virulence and wild-type cycloheximide resistance; putative GTP-binding motif; similar to S. cerevisiae Yor165Wp; in gene cluster that encodes enzymes of GlcNAc catabolism; no human or murine homolog || 1 0.02 0.02 -0.17 0.33 -0.08 -0.21 -0.50 -0.38 -0.04 -0.24 -0.61 -0.22 -0.43 -0.36 0.01 -0.36
7108 || orf19.2771 || BEM3 || || Putative GTPase-activating protein (GAP) for Rho-type GTPase Cdc42p; involved in cell signaling pathways that control cell polarity; similar to S. cerevisiae Bem3p || 1 0.13 0.18 -0.07 0.20 0.12 -0.33 -0.43 -0.30 -0.21 -0.00 -0.40 0.14 -0.55 -0.32 -0.21 -0.16
7109 || orf19.4041 || PEX4 || || Putative peroxisomal ubiquitin conjugating enzyme; regulated by Sef1, Sfu1, and Hap43; rat catheter biofilm induced; Spider biofilm induced || 1 0.31 0.67 0.01 0.58 0.09 -1.44 -0.21 -0.48 -0.18 0.15 -0.78 -0.60 -1.42 -0.78 -0.40 -0.24
7110 || orf19.4041 || PEX4 || || Putative peroxisomal ubiquitin conjugating enzyme; regulated by Sef1, Sfu1, and Hap43; rat catheter biofilm induced; Spider biofilm induced || 1 0.63 0.44 0.35 0.84 0.10 -1.02 -0.11 -0.06 0.35 0.52 -0.82 -0.48 -1.02 -0.63 -0.17 -0.22
7111 || orf19.290 || KRE5 || || UDP-glucose:glycoprotein glucosyltransferase; 1,6-beta-D-glucan biosynthesis, hyphal growth, virulence in mouse IV model; partially complements S. cerevisiae kre5 mutant defects; flow biofilm repressed, Bcr1-repressed in RPMI a/a biofilms || 1 0.17 0.19 0.14 0.07 -0.12 -0.17 -0.25 -0.03 -0.60 0.06 -0.33 -0.52 -0.59 -0.17 -0.34 0.10
7112 || orf19.1557 || || || Ortholog(s) have S-adenosylmethionine-dependent methyltransferase activity, role in protein methylation and cytosol, nucleus localization || 1 0.21 -0.15 0.15 0.47 0.22 -0.31 -0.01 0.13 0.07 -0.07 -0.24 -0.40 -1.15 -0.09 -0.81 -0.09
7113 || orf19.3318 || || || Ortholog(s) have cytoplasm localization || 1 0.26 0.11 0.45 0.63 0.42 -0.05 -0.45 -0.38 0.07 -0.26 -0.89 -0.36 -0.81 -0.08 -0.95 -0.01
7114 || orf19.5628 || || || Mitochondrial dicarboxylate transporter; possibly an essential gene, disruptants not obtained by UAU1 method || 1 0.48 0.57 0.38 0.23 0.30 0.73 -0.14 0.03 -0.57 -0.41 -0.58 -0.80 -0.30 -0.67 -1.27 -0.44
7115 || orf19.2770.1 || SOD1 || || Cytosolic copper- and zinc-containing superoxide dismutase; role in protection from oxidative stress; required for full virulence; alkaline induced by Rim101; induced by human blood; rat catheter, flow model and Spider biofilm repressed || 1 0.36 0.32 0.63 1.02 0.67 0.87 -0.17 -0.03 -0.54 -0.46 -0.61 -0.77 -1.05 -1.05 -2.48 -0.89
7116 || orf19.2770.1 || SOD1 || || Cytosolic copper- and zinc-containing superoxide dismutase; role in protection from oxidative stress; required for full virulence; alkaline induced by Rim101; induced by human blood; rat catheter, flow model and Spider biofilm repressed || 1 0.27 0.17 0.51 0.73 0.52 -0.20 -0.10 -0.46 -0.41 -0.69 -0.87 -1.28 -1.16 -2.59 -1.01
7117 || orf19.969 || || || Ortholog(s) have ribose phosphate diphosphokinase activity, role in 5-phosphoribose 1-diphosphate biosynthetic process, cytokinesis, fungal-type cell wall organization and cytosol, nucleus localization || 1 0.19 0.21 0.46 0.40 0.44 0.75 -0.24 -0.04 -0.08 0.56 -0.39 -0.45 -0.92 -0.14 -0.79 -0.43
7118 || orf19.6291 || || || Ortholog(s) have DNA binding, DNA-dependent ATPase activity, chromatin binding activity || 1 0.05 -0.01 0.12 0.19 0.24 0.13 -0.34 -0.11 -0.24 0.75 -0.04 -0.48 -0.46 0.04 -1.05 -0.24
7119 || orf19.1043 || || || Ortholog(s) have lysophosphatidic acid acyltransferase activity and role in cellular response to cadmium ion, cellular triglyceride homeostasis, detoxification of cadmium ion, lipid particle organization, protein targeting to vacuole || 1 0.14 0.31 0.22 -0.39 1.25 0.59 -1.81 -1.34 -0.84 -0.38 -1.50 -0.78 -1.03 -0.27 -1.97 -0.46
7120 || orf19.5906 || ADE2 || || Phosphoribosylaminoimadazole carboxylase; role in adenine biosynthesis; required for normal growth and virulence in immunosuppressed mouse infection; not induced in GCN response, in contrast to S. cerevisiae ADE2; stationary phase-enriched || 1 -0.01 -0.07 -0.02 -0.13 0.37 0.46 -0.70 -0.33 -0.52 -0.08 -0.53 -0.04 -1.19 0.24 -0.76 0.17
7121 || orf19.3103 || || || Ortholog(s) have RNA polymerase III activity, role in tRNA transcription from RNA polymerase III promoter and DNA-directed RNA polymerase III complex, cytoplasm localization || 1 -0.24 -0.21 -0.33 -0.28 -0.06 0.20 -0.45 -0.48 -0.49 -0.09 -0.75 -0.47 -1.14 -0.59 -0.94 -0.10
7122 || orf19.6038 || UGA32 || || Predicted Zn(II)2Cys6 transcription factor; has similarity to S. cerevisiae Uga3, a transcription factor involved in the regulation of gamma-aminobutyrate metabolism genes; rat catheter biofilm induced || 1 0.29 0.04 0.02 -0.22 -0.40 0.08 -0.61 -0.56 -0.33 -0.75 -0.54 -0.59 -1.28 -0.52 -1.16 -0.14
7123 || orf19.6038 || UGA32 || || Predicted Zn(II)2Cys6 transcription factor; has similarity to S. cerevisiae Uga3, a transcription factor involved in the regulation of gamma-aminobutyrate metabolism genes; rat catheter biofilm induced || 1 0.07 -0.02 -0.43 -0.85 -0.03 0.33 -0.45 -0.44 0.02 -0.73 -0.37 -0.15 -1.33 -0.35 -1.10 -0.14
7124 || orf19.5828 || || || Ortholog(s) have pre-mRNA branch point binding activity, role in generation of catalytic spliceosome for first transesterification step, mRNA branch site recognition, mRNA cis splicing, via spliceosome and commitment complex localization || 1 0.14 -0.26 0.19 0.03 0.22 -0.05 -0.12 -0.04 0.15 -0.41 -0.16 -0.18 -0.26 -0.28 -0.30 -0.34
7125 || orf19.4463 || || || Ortholog of Candida albicans WO-1 : CAWG_01004 || 1 0.40 0.02 0.50 -0.11 0.55 -0.38 -0.03 -0.87 0.21 -0.33 -0.74 -0.26 -0.05 -0.26 -0.49 -0.44
7126 || orf19.1944 || GPR1 || || Plasma membrane G-protein-coupled receptor of the cAMP-PKA pathway; required for WT hyphal growth; reports differ on role in cAMP-mediated glucose signaling; Gpr1 C terminus binds Gpa2; regulates HWP1 and ECE1; flow model biofilm induced || 1 0.16 0.30 0.47 1.02 -0.23 -0.59 -0.09 -0.66 -1.61 -0.59 -0.33 -1.07 0.69 0.11 0.19 -0.55
7127 || orf19.7666 || || || Predicted membrane transporter, member of the anion:cation symporter (ACS) family, major facilitator superfamily (MFS) || 1 -0.26 -0.60 0.28 0.82 -0.36 0.06 -1.42 -0.56 -0.87 -0.68 -0.38 -1.22 -0.73 -0.51 0.07 -0.69
7128 || orf19.5006.1 || || || Ortholog(s) have SNAP receptor activity and role in Golgi to plasma membrane transport, cytokinesis, endocytosis, exocytosis, vesicle fusion || 1 0.18 0.05 0.16 0.25 -0.18 0.10 -0.55 -0.50 -0.20 -0.41 -0.59 -0.24 -0.62 0.22 0.03 -0.33
7129 || orf19.5876 || || || Protein of unknown function; Cyr1-repressed; induced by alpha pheromone in SpiderM medium; rat catheter and Spider biofilm induced || 1 0.33 0.36 0.23 0.07 0.34 0.12 -0.67 -1.18 -0.97 -0.81 -1.56 -1.14 -1.08 -0.05 0.55 -0.31
7130 || orf19.5751 || ORM1 || || Putative endoplasmic reticulum membrane protein; Hap43p-repressed gene; mutation confers hypersensitivity to aureobasidin A || 1 -0.19 -0.03 0.06 0.17 -0.09 -0.16 -0.40 -0.71 -0.37 -0.20 -0.42 -0.60 -0.38 -0.02 0.22 -0.22
7131 || orf19.6000 || CDR1 || || Multidrug transporter of ABC superfamily; transports phospholipids in an in-to-out direction; induced by beta-estradiol, progesterone, corticosteroid, or cholesterol; Spider biofilm induced || 1 0.00 -0.04 0.33 0.67 -1.03 -0.42 -0.83 -1.03 -1.99 -0.70 -1.63 -1.89 -0.33 0.42 0.68 -0.41
7132 || orf19.6000 || CDR1 || || Multidrug transporter of ABC superfamily; transports phospholipids in an in-to-out direction; induced by beta-estradiol, progesterone, corticosteroid, or cholesterol; Spider biofilm induced || 1 0.17 0.12 0.76 0.98 -0.89 -0.07 -0.67 -0.80 -1.43 -0.30 -1.26 -1.25 -0.20 0.90 0.96 -0.14
7133 || orf19.4707 || || || Putative secreted acid sphingomyelin phosphodiesterase; possible Kex2p substrate || 1 0.08 -0.15 0.81 0.24 -0.46 -0.55 -0.89 -0.38 -0.35 -0.58 -1.00 -0.90 -0.43 0.56 0.47 -0.04
7134 || orf19.1008 || || || Ortholog of Candida albicans WO-1 : CAWG_01856 || 1 0.05 -0.01 1.53 0.19 -0.43 0.03 -0.40 0.09 -0.41 -0.05 -0.46 0.26 -0.67 -0.41 -0.47 -0.29
7135 || orf19.7340 || || || Protein of unknown function; possibly C. albicans specific; Spider biofilm induced || 1 0.02 0.44 2.12 0.75 -0.56 0.44 -0.40 -0.50 0.03 -0.10 -0.42 0.42 0.04 -0.40 -0.05 -0.26
7136 || orf19.5461 || || || Ortholog of Candida albicans WO-1 : CAWG_02350 || 1 0.33 0.51 1.15 0.38 -0.30 0.44 -0.78 -0.49 -0.04 -0.16 -0.39 0.21 -0.01 -0.35 -0.59 -0.59
7137 || orf19.133 || || || Protein of unknown function; induced by nitric oxide independent of Yhb1p || 1 0.40 0.21 1.04 0.19 0.00 0.22 -0.26 -0.05 0.31 -0.53 -0.20 0.30 0.07 0.12 0.14 -0.32
7138 || orf19.1981 || IMP2 || || Predicted subunit of the mitochondrial inner membrane peptidase complex involved in protein targeting to mitochondria || 1 -0.00 -0.21 0.32 0.09 0.10 0.26 -0.10 -0.13 0.18 -0.40 -0.19 0.05 0.01 -0.43 0.19 0.23
7139 || orf19.2580 || HST2 || || Putative histone deacetylase; role in regulation of white-opaque switch; Spider biofilm induced || 1 -0.37 -0.23 0.45 0.18 0.12 0.21 -0.34 -0.84 0.27 -0.44 -0.65 0.03 -0.05 -0.49 0.43 0.20
7140 || orf19.3342 || || || Ortholog(s) have role in protein deubiquitination and cytoplasm, nucleus localization || 1 -0.12 0.00 0.70 0.01 0.35 0.09 -0.40 -0.39 0.07 -0.17 -0.25 0.09 0.15 -0.11 0.27 0.44
7141 || orf19.5533 || || || Ortholog(s) have guanyl-nucleotide exchange factor activity, ubiquitin binding activity || 1 -0.19 -0.06 0.61 0.21 0.39 0.33 -0.59 -0.34 0.03 -0.24 -0.23 0.07 -0.05 -0.21 -0.02 0.51
7142 || orf19.3332 || || || Ortholog of Bre4 in S. cerevisiae has a role in brefeldin A resistence; a drug that affect intracellular transport; Spider biofilm induced || 1 -0.24 -0.34 0.66 0.45 0.38 0.67 -0.56 -0.62 -0.17 -0.34 -0.05 0.55 -0.38 -0.45 0.24 0.68
7143 || orf19.3329 || || || Ortholog(s) have sphingosine-1-phosphate phosphatase activity, role in calcium-mediated signaling and endoplasmic reticulum localization || 1 -0.25 -0.33 0.83 0.62 0.32 0.47 -0.12 -0.35 0.05 -0.32 0.18 0.22 -0.28 -0.08 0.18 0.56
7144 || orf19.3881 || || || Ortholog of C. dubliniensis CD36 : Cd36_31790, C. parapsilosis CDC317 : CPAR2_204900, Candida tenuis NRRL Y-1498 : CANTEDRAFT_136864 and Debaryomyces hansenii CBS767 : DEHA2F13200g || 1 -0.26 -0.21 0.85 0.47 0.04 0.78 -0.14 -0.20 0.12 -0.40 -0.35 0.04 -0.29 -0.07 0.08 0.28
7145 || orf19.4690 || || || NRAMP metal ion transporter domain-containing protein; induced by nitric oxide independent of Yhb1; flow model biofilm induced; rat catheter biofilm repressed || 1 -0.25 -0.10 1.22 2.02 0.88 0.63 -0.37 -0.53 -0.00 -1.36 -0.59 0.46 -0.17 -0.24 0.18 0.73
7146 || orf19.1464 || BMT5 || || Putative beta-mannosyltransferase involved in beta-1,2-mannosylation of phospholipomannan; 9-member family includes Bmt1, Bmt2, Bmt3, and Bmtp with roles in mannosylation of cell wall phosphopeptidomannan; Spider biofilm induced || 1 -0.17 0.16 0.78 0.65 0.04 0.10 -0.06 -0.26 0.12 -0.82 -0.15 0.27 0.12 0.29 0.05 0.45
7147 || orf19.384 || || || Ortholog(s) have Golgi apparatus, cytosol, nucleus localization || 1 -0.19 0.27 0.92 0.56 0.13 0.32 -0.74 -0.55 0.05 -0.65 -0.48 0.59 0.30 -0.19 -0.12 -0.11
7148 || orf19.3450.1 || || || Ortholog of C. dubliniensis CD36 : Cd36_61450, C. parapsilosis CDC317 : CPAR2_602710, Candida tenuis NRRL Y-1498 : cten_CGOB_00240 and Pichia stipitis Pignal : psti_CGOB_00191 || 1 0.13 0.07 0.42 0.35 0.31 0.47 -0.40 -0.44 0.33 -0.62 -0.09 0.47 0.07 -0.02 -0.17 0.23
7149 || orf19.7565 || GNP3 || || Putative high-affinity glutamine permease; fungal-specific (no human or murine homolog) || 1 -0.03 0.06 0.61 0.20 0.31 0.31 -0.38 -0.60 0.25 -0.62 -0.34 0.42 0.35 -0.25 -0.12 0.21
7150 || orf19.4535 || PTR3 || || Protein similar to S. cerevisiae Ptr3p, which is a sensor of external amino acids; expression upregulated in an ssr1 null mutant || 1 -0.08 -0.17 0.35 0.10 0.34 0.35 -0.36 -0.38 0.10 -0.60 -0.33 0.32 0.07 -0.37 0.06 0.06
7151 || orf19.5504 || || || Ortholog of C. dubliniensis CD36 : Cd36_73400, C. parapsilosis CDC317 : CPAR2_703180, Candida tenuis NRRL Y-1498 : CANTEDRAFT_104803 and Debaryomyces hansenii CBS767 : DEHA2A04466g || 1 0.10 -0.03 0.16 0.14 0.17 0.36 -0.39 -0.40 0.06 -0.66 -0.35 0.31 0.10 0.17 0.28 0.23
7152 || orf19.6596 || || || Putative esterase; possibly transcriptionally regulated by Tac1; induced by Mnl1 under weak acid stress; protein present in exponential and stationary growth phase yeast cultures; Spider biofilm repressed || 1 0.02 -0.13 0.27 0.35 0.20 0.55 -0.83 -0.60 -0.27 -0.86 -0.17 0.06 -0.07 -0.07 0.37 0.10
7153 || orf19.1240 || || || Ortholog of S. cerevisiae : YPR117W, C. glabrata CBS138 : CAGL0D04510g, C. dubliniensis CD36 : Cd36_45200, C. parapsilosis CDC317 : CPAR2_500480 and Candida tenuis NRRL Y-1498 : CANTEDRAFT_120679 || 1 0.00 -0.11 0.60 0.23 0.13 0.74 -0.43 -0.60 -0.00 -0.51 -0.37 0.03 0.01 -0.06 0.44 0.26
7154 || orf19.1253 || PHO4 || || bHLH transcription factor of the myc-family; required for growth in medium lacking phosphate and for resistance to copper and Phloxine B; induced by Mnl1 under weak acid stress || 1 -0.17 -0.10 0.38 0.10 -0.04 0.42 -0.47 -0.65 -0.20 -0.37 -0.59 0.33 0.16 -0.20 0.39 -0.19
7155 || orf19.1339 || CPY1 || || Carboxypeptidase Y; transcript regulated at yeast-hypha transition or macrophage response; induced human neutrophils; regulated by Gcn2 and Gcn4; putative N-glycosylation || 1 -0.37 -0.44 0.31 0.51 -0.23 0.66 -0.68 -0.89 -0.56 -1.10 -0.45 0.36 0.45 -0.14 0.49 0.04
7156 || orf19.1586 || FGR22 || || Putative phosphatidylinositol-specific phospholipase C (PI-PLC); predicted type 2 membrane protein; no S. cerevisiae ortholog; role in, and regulated by, filamentation, Hap43p; almost identical to orf19.5797 || 1 0.29 0.06 0.17 0.17 -0.00 0.34 -0.37 -0.22 -0.20 -0.40 -0.52 -0.12 -0.41 0.43 0.10 0.04
7157 || orf19.6308 || || || Ortholog of Candida albicans WO-1 : CAWG_01818 || 1 -0.01 -0.04 0.44 0.59 0.42 0.23 -0.58 -0.48 -0.18 -0.72 -0.56 0.30 -0.68 0.49 0.26 0.04
7158 || orf19.5118 || SDS24 || || Protein similar to S. cerevisiae Sds24 involved in cell separation during budding; transcript regulated by Mig1 and Tup1; fluconazole-induced; flow model biofilm induced || 1 -0.06 0.14 0.67 0.15 0.43 0.16 -0.38 -0.41 -0.00 -0.88 -0.55 -0.03 -0.65 0.05 0.41 -0.53
7159 || orf19.5118 || SDS24 || || Protein similar to S. cerevisiae Sds24 involved in cell separation during budding; transcript regulated by Mig1 and Tup1; fluconazole-induced; flow model biofilm induced || 1 0.24 0.30 0.78 0.37 0.42 0.21 -0.33 -0.49 -0.05 -0.92 -0.59 -0.05 -0.42 -0.06 0.38 -0.40
7160 || orf19.1800 || || || Protein of unknown function; Spider biofilm induced || 1 0.40 0.23 0.80 0.64 0.20 0.84 -0.42 -0.75 -0.12 -1.12 -0.37 -0.72 -0.51 0.30 -0.00 0.03
7161 || orf19.314 || || || Ortholog of S. cerevisiae : STB6, C. dubliniensis CD36 : Cd36_83110, C. parapsilosis CDC317 : CPAR2_103210, Candida tenuis NRRL Y-1498 : CANTEDRAFT_133418 and Debaryomyces hansenii CBS767 : DEHA2G08382g || 1 0.29 0.29 0.28 0.23 0.35 0.27 -0.34 -0.38 0.00 -0.48 -0.58 -0.03 -0.54 -0.36 -0.04 0.15
7162 || orf19.6274 || PBR1 || || Protein of unknown function; required for cohesion, adhesion, and RPMI biofilm formation; induced by alpha pheromone in white cells; fluconazole-induced; Spider biofilm induced || 1 -0.15 -0.08 0.40 0.63 0.61 0.58 -0.30 -0.65 0.28 -0.48 -0.62 -0.34 -0.54 -0.96 0.79 -0.52
7163 || orf19.1150 || || || GATA-like transcription factor; oral infection induced; mutant has reduced capacity to damage oral epithelial cells; regulated by Gcn2 and Gcn4; Spider biofilm induced || 1 0.36 -0.47 0.36 0.62 0.25 0.65 -0.25 -0.60 0.56 -0.55 -0.25 -0.35 -0.42 -0.43 0.06 -0.51
7164 || orf19.4067 || FGR18 || || Protein lacking an ortholog in S. cerevisiae; transposon mutation affects filamentous growth || 1 0.18 0.50 0.86 0.31 -0.05 1.54 -0.57 -0.53 0.73 -0.44 -0.72 -0.77 -0.03 -0.50 0.01
7165 || orf19.7666 || || || Predicted membrane transporter, member of the anion:cation symporter (ACS) family, major facilitator superfamily (MFS) || 1 -0.08 0.51 0.93 1.11 -0.28 0.93 -0.97 -0.44 0.65 -0.30 -0.81 -0.16 -0.69 -0.52 0.22 -0.14
7166 || orf19.4531 || || || Putative PDR-subfamily ABC transporter; Spider biofilm induced || 1 -0.32 -0.14 1.23 1.19 0.10 0.57 -0.46 -0.44 0.81 -0.05 -0.53 0.20 -0.20 -0.35 0.19 -0.27
7167 || orf19.5037 || HRQ2 || || Protein of unknown function; mutants are viable; rat catheter and Spider biofilm induced || 1 -0.10 -0.00 1.09 1.03 -0.29 0.61 -0.24 -0.69 0.41 -0.34 -0.49 0.17 -0.10 -0.22 0.70 -0.04
7168 || orf19.6398 || || || S. pombe ortholog SPBC460.04c is a predicted sulfonate/alpha-ketoglutare dioxygenase; induced by nitric oxide; Spider biofilm induced || 1 -0.37 -0.44 1.90 1.61 -0.71 0.27 -1.01 -1.59 0.51 -0.34 -1.22 0.14 -0.41 -0.26 1.32 0.02
7169 || orf19.5037 || HRQ2 || || Protein of unknown function; mutants are viable; rat catheter and Spider biofilm induced || 1 -0.22 -0.60 0.70 0.81 -0.14 0.46 -0.65 -0.69 0.38 -0.40 -1.26 -0.17 -0.58 -0.36 0.49 -0.63
7170 || orf19.7663 || || || Ortholog(s) have role in homologous chromosome segregation, protein localization to nucleolar rDNA repeats, rDNA condensation and monopolin complex, nuclear envelope, nucleolus localization || 1 -0.01 0.00 0.44 0.46 0.09 0.50 -0.55 -0.41 -0.03 -0.10 -0.33 -0.06 -0.47 -0.06 -0.02 -0.13
7171 || orf19.6997 || ATO5 || || Putative fungal-specific transmembrane protein || 1 -0.19 -0.08 0.53 0.51 -0.07 1.02 -0.37 -0.49 0.18 0.01 -0.46 -0.01 -0.06 -0.09 0.06 -0.48
7172 || orf19.2241 || PST1 || || Putative 1,4-benzoquinone reductase; hyphal-induced; regulated by Cyr1, Ras1, Efg1, Nrg1, Rfg1, Tup1; Hap43-induced; Spider biofilm induced || 1 -0.76 -0.67 1.18 1.16 0.65 2.09 -1.51 -1.23 0.43 -0.21 -1.45 -0.54 -0.77 -0.38 0.49 -0.77
7173 || orf19.6422 || SSY5 || || Ortholog(s) have serine-type endopeptidase activity, role in protein processing, response to amino acid and extrinsic to plasma membrane localization || 1 -0.09 -0.26 0.47 0.35 0.28 0.73 -0.59 -0.66 0.36 -0.09 -0.78 -0.12 -0.17 -0.34 -0.12 -0.38
7174 || orf19.4229 || || || Putative polyphosphate phosphatase; role in hydrolysis of diphosphorylated inositol polyphosphates and diadenosine polyphosphates; Spider biofilm induced || 1 -0.14 -0.15 0.21 0.14 0.05 0.34 -0.11 -0.37 0.18 -0.13 -0.43 -0.14 -0.26 -0.10 -0.10 -0.29
7175 || orf19.3894 || || || Putative inositol oxygenase; mutation confers hypersensitivity to toxic ergosterol analog; Spider biofilm induced || 1 -0.35 -0.55 0.50 0.35 0.16 0.80 -0.17 -0.62 -0.19 0.23 -0.78 -0.21 -0.33 -0.09 -0.04 -0.59
7176 || orf19.5633 || || || F-box domain-containing protein; flow model biofilm induced || 1 -0.27 -0.16 0.74 0.75 0.35 0.83 -0.42 -0.51 -0.04 -0.59 -0.64 -0.34 0.32 0.45 0.50 0.00
7177 || orf19.5633 || || || F-box domain-containing protein; flow model biofilm induced || 1 -0.40 -0.23 1.08 0.66 0.47 0.75 -0.62 -0.68 -0.18 -0.65 -0.82 -0.48 0.29 0.53 0.46 -0.19
7178 || orf19.3900 || || || Ortholog(s) have role in mitochondrial fusion and integral to mitochondrial outer membrane localization || 1 -0.08 0.06 0.66 0.35 0.22 0.42 -0.28 -0.21 0.07 -0.10 -0.39 -0.07 0.06 -0.04 -0.00 -0.00
7179 || orf19.3900 || || || Ortholog(s) have role in mitochondrial fusion and integral to mitochondrial outer membrane localization || 1 -0.06 -0.06 0.65 0.21 0.24 0.55 -0.30 -0.18 0.21 -0.24 -0.51 -0.05 0.28 -0.02 0.08 -0.15
7180 || orf19.3176 || RIM21 || || Plasma membrane pH-sensor involved in the Rim101 pH response pathway; required for processing and activation of Rim101 and for alkaline pH-induced hyphal growth; Spider biofilm induced || 1 0.12 -0.00 0.78 0.26 0.57 0.79 -0.51 -0.38 0.44 -0.35 -0.37 -0.01 0.05 -0.29 0.20 -0.17
7181 || orf19.1950 || || || Ortholog(s) have phosphatase activity || 1 -0.09 0.22 0.40 0.16 0.57 0.73 -0.01 -0.24 0.12 -0.49 -0.49 -0.10 -0.00 -0.22 0.48 -0.38
7182 || orf19.4795 || || || Protein of unknown function; Sef1-, Sfu1-, and Hap43 regulated; Spider biofilm induced || 1 0.15 0.33 0.87 0.63 1.22 1.21 -0.52 -0.33 0.22 -0.42 -1.43 -0.57 -0.20 -0.06 0.81 -0.22
7183 || orf19.431 || ZCF2 || || Zn(II)2Cys6 transcription factor; regulates sulfite tolerance through expression of SSU1 and CDG1; Hap43-repressed; Spider biofilm induced || 1 0.10 -0.01 1.00 0.31 0.36 0.90 -0.32 -0.27 0.49 -0.79 -1.33 -0.92 0.09 -0.14 0.37 -0.18
7184 || orf19.5876 || || || Protein of unknown function; Cyr1-repressed; induced by alpha pheromone in SpiderM medium; rat catheter and Spider biofilm induced || 1 0.82 0.75 0.91 0.84 0.48 0.75 -0.43 -0.64 0.05 -0.26 -1.09 -0.84 -0.40 0.13 0.74 0.02
7185 || orf19.896 || CHK1 || || Histidine kinase; 2-component signaling, cell wall synthesis; hyphal growth defect; avirulent in mouse, not rat vaginal infection; phagocytosis rate increased; Spider biofilm induced; required for RPMI biofilm; Bcr1-induced in a/a biofilm || 1 0.66 0.08 0.43 0.61 0.71 1.20 -0.21 -0.43 0.17 -0.15 -0.56 -0.70 0.07 0.26 0.63 -0.18
7186 || orf19.6517 || RAD14 || || Putative DNA repair protein; transcription is regulated upon yeast-hyphal switch; flucytosine repressed || 1 -0.41 0.63 0.63 0.70 0.47 1.26 -0.17 -0.23 0.45 -0.16 0.05 0.04 -0.33 -0.05 0.50 -0.02
7187 || orf19.6239 || || || Putative serine/threonine protein kinase; possibly an essential gene, disruptants not obtained by UAU1 method || 1 0.14 0.23 0.61 0.31 0.22 0.53 -0.19 -0.22 0.18 0.28 -0.11 0.10 -0.42 0.25 0.15 0.16
7188 || orf19.872 || || || Ortholog of C. dubliniensis CD36 : Cd36_18230, Debaryomyces hansenii CBS767 : DEHA2E20636g, Pichia stipitis Pignal : PICST_66811 and Spathaspora passalidarum NRRL Y-27907 : SPAPADRAFT_60843 || 1 0.15 0.27 0.55 0.34 0.26 0.86 -0.22 -0.12 0.40 -0.05 -0.40 -0.04 -0.28 0.45 0.12 0.42
7189 || orf19.1933 || || || Ortholog(s) have role in peroxisome organization and peroxisomal membrane localization || 1 0.01 -0.21 0.61 0.27 0.51 1.07 -0.42 -0.38 0.16 -0.02 -0.08 0.36 -0.38 0.27 0.34 0.50
7190 || orf19.872 || || || Ortholog of C. dubliniensis CD36 : Cd36_18230, Debaryomyces hansenii CBS767 : DEHA2E20636g, Pichia stipitis Pignal : PICST_66811 and Spathaspora passalidarum NRRL Y-27907 : SPAPADRAFT_60843 || 1 0.14 0.10 0.46 -0.03 0.30 0.68 -0.44 -0.35 0.08 -0.31 -0.26 0.02 -0.23 0.03 -0.17 0.45
7191 || orf19.6596 || || || Putative esterase; possibly transcriptionally regulated by Tac1; induced by Mnl1 under weak acid stress; protein present in exponential and stationary growth phase yeast cultures; Spider biofilm repressed || 1 -0.14 -0.05 0.52 0.39 0.08 0.63 -0.25 -0.02 -0.11 -0.79 0.04 0.07 -0.23 0.06 0.03 -0.10
7192 || orf19.4740 || || || Ortholog(s) have aminoacyl-tRNA hydrolase activity, role in mitochondrial translation and mitochondrion localization || 1 -0.03 -0.03 -0.15 0.42 -0.26 0.69 -0.05 0.04 -0.19 -0.28 -0.21 -0.25 -0.15 0.10 -0.13 0.22
7193 || orf19.2072 || || || Ortholog(s) have (R)-carnitine transmembrane transporter activity, choline transmembrane transporter activity, ethanolamine transmembrane transporter activity || 1 0.13 -0.11 0.34 1.23 0.14 1.24 -0.54 -0.24 -0.69 -0.13 -0.83 -0.67 -0.93 0.43 -0.05 0.76
7194 || orf19.1863 || || || Has domain(s) with predicted Rho guanyl-nucleotide exchange factor activity, role in regulation of Rho protein signal transduction and intracellular localization || 1 0.22 -0.03 1.37 -0.11 1.18 -0.40 0.26 -0.81 -0.30 -0.59 -0.02 -0.65 -0.84 -0.05
7195 || orf19.2563 || || || Ortholog(s) have U6 snRNA binding activity, role in spliceosomal complex assembly, spliceosomal tri-snRNP complex assembly and U6 snRNP localization || 1 0.25 0.05 0.64 0.57 0.33 0.70 -0.47 -0.09 -0.37 -0.09 -0.41 -0.09 -0.21 -0.29 -0.13 -0.03
7196 || orf19.4601 || || || Putative RNA polymerase III transcription initiation factor complex (TFIIIC) subunit; possibly an essential gene, disruptants not obtained by UAU1 method || 1 0.21 0.25 0.38 0.65 -0.13 0.63 -0.45 0.16 -0.24 -0.15 -0.22 -0.02 -0.09 -0.00 -0.31 0.04
7197 || orf19.4548 || MAK32 || || Putative protein involved in the structural stability of L-A double-stranded RNA-containing particles; downregulated upon adherence to polystyrene || 1 -0.10 0.19 0.70 0.18 0.13 0.60 -0.50 -0.41 -0.09 -0.09 -0.38 0.13 0.03 -0.00 -0.14 0.02
7198 || orf19.1890 || || || Ortholog(s) have role in medium-chain fatty acid biosynthetic process || 1 0.20 0.49 0.72 0.28 -0.04 0.99 -1.31 -1.18 -0.41 0.23 -0.94 0.05 -0.32 -0.05 0.05 0.24
7199 || orf19.7627 || || || Ortholog(s) have role in establishment of cell polarity, mycelium development, spore germination and endoplasmic reticulum, hyphal tip, mitochondrion, plasma membrane localization || 1 0.41 0.27 0.40 0.35 0.03 0.40 -0.35 -0.46 -0.03 0.16 -0.67 0.28 -0.40 -0.17 -0.08 0.26
7200 || orf19.7660 || VPS52 || || Protein required for hyphal growth; has similarity to S. cerevisiae Vps52p || 1 0.63 0.24 1.04 0.60 0.13 0.57 -0.52 -0.87 0.03 -0.14 -0.29 0.40 -0.62 -0.05 -0.20 0.33
7201 || orf19.6020 || || || Ortholog(s) have Atg8 ligase activity and role in C-terminal protein lipidation, CVT pathway, autophagic vacuole assembly, cellular response to nitrogen starvation, mitochondrion degradation, piecemeal microautophagy of nucleus || 1 0.45 0.27 0.66 0.58 -0.01 0.68 -0.46 -0.72 -0.04 -0.28 -0.42 0.14 -0.51 -0.17 0.32 0.02
7202 || orf19.1332 || SNG4 || || Putative membrane transporter; Hap43-induced; inducd by Mnl1p under weak acid stress; shows Mob2-dependent hyphal regulation || 1 0.16 0.02 0.39 0.31 -0.17 0.26 -0.28 -0.09 -0.32 0.00 -0.13 0.08 -0.28 -0.38 0.23 0.02
7203 || orf19.7660 || VPS52 || || Protein required for hyphal growth; has similarity to S. cerevisiae Vps52p || 1 0.55 0.57 0.81 0.72 0.01 0.38 -0.78 -0.95 -0.10 -0.10 -0.50 0.34 -0.83 -1.58 -0.23 0.26
7204 || orf19.1675 || || || Ortholog(s) have role in positive regulation of catalytic activity || 1 0.48 0.23 0.41 0.70 0.07 0.17 -0.68 -0.54 -0.43 -0.22 -0.27 0.47 -0.45 -0.83 0.06 -0.04
7205 || orf19.1675 || || || Ortholog(s) have role in positive regulation of catalytic activity || 1 0.43 0.24 0.81 1.07 -0.22 0.09 -0.91 -0.72 -0.42 -0.17 -0.37 0.51 -0.60 -0.92 -0.36 -0.60
7206 || orf19.2771 || BEM3 || || Putative GTPase-activating protein (GAP) for Rho-type GTPase Cdc42p; involved in cell signaling pathways that control cell polarity; similar to S. cerevisiae Bem3p || 1 0.22 0.10 0.25 0.59 0.06 -0.16 -0.35 -0.34 -0.33 -0.01 -0.53 0.19 -0.36 -0.38 -0.25 -0.04
7207 || orf19.5278 || || || Protein of unknown function; Spider biofilm induced || 1 0.51 0.52 0.64 1.06 0.11 0.20 -0.79 -0.38 -0.42 0.34 -0.49 0.51 -0.60 -0.37 0.16 0.01
7208 || orf19.4954 || || || Ortholog(s) have endoplasmic reticulum, integral to membrane localization || 1 0.17 0.22 0.41 0.85 -0.11 -0.24 -0.84 -0.57 -0.46 0.01 -0.05 0.24 -0.04 -0.32 -0.12 -0.00
7209 || orf19.1236 || GVP36 || || BAR domain protein; ocalizes to early and late Golgi vesicles; predicted role in adaptation to varying nutrient concentrations, fluid-phase endocytosis, actin cytoskeleton polarization and vacuole biogenesis; rat catheter biofilm repressed || 1 0.23 0.19 0.28 0.34 -0.14 0.06 -0.69 -0.31 -0.49 0.28 -0.16 0.17 -0.55 -0.08 -0.10 0.11
7210 || orf19.2946 || HNM4 || || Putative choline permease; fungal-specific (no human or murine homolog) || 1 0.26 0.14 0.72 1.11 0.40 0.99 -0.43 -1.56 -2.06 -0.32 -1.03 0.38 -1.23 -0.57 0.11
7211 || orf19.5121 || OPT5 || || Oligopeptide transporter; fungal-specific (no human or murine homolog); induced by BSA, but not by tetrapeptide or pentapeptide || 1 0.07 -0.30 0.81 0.64 0.44 0.06 -0.38 -0.25 -1.33 0.11 -0.87 0.58 -0.66 -0.40 -0.32 0.75
7212 || orf19.4217 || || || Ortholog of Candida tropicalis MYA-3404 : CTRG_03197, Candida lusitaniae ATCC 42720 : CLUG_02837 and Candida albicans WO-1 : CAWG_04597 || 1 -0.30 -0.25 0.71 0.51 0.04 0.03 -0.28 0.28 -0.22 -0.14 -0.34 0.18 -0.10 -0.13 -0.52
7213 || orf19.664 || || || Ortholog of C. dubliniensis CD36 : Cd36_10680, Debaryomyces hansenii CBS767 : DEHA2E14058g, Pichia stipitis Pignal : PICST_29620 and Spathaspora passalidarum NRRL Y-27907 : SPAPADRAFT_146037 || 1 -0.19 0.18 0.67 0.55 -0.01 -0.18 -0.34 0.05 0.06 -0.07 -0.16 0.25 -0.19 -0.66 -0.23 -0.40
7214 || orf19.3375 || || || Ortholog of C. dubliniensis CD36 : Cd36_43270 and Candida albicans WO-1 : CAWG_03460 || 1 -0.38 0.34 -0.03 1.38 0.31 -0.40 -0.60 -0.35 -0.35 0.04 -0.44 -0.31 -0.05 -0.66 -1.64
7215 || orf19.4688 || DAG7 || || Secretory protein; a-specific, alpha-factor induced; mutation confers hypersensitivity to toxic ergosterol analog; fluconazole-induced; induced during chlamydospore formation in C. albicans and C. dubliniensis || 1 -0.27 -0.25 0.24 1.19 0.35 0.27 -0.51 -0.44 -0.03 0.06 -0.64 0.01 -0.49 -0.64 -0.22 -1.24
7216 || orf19.4688 || DAG7 || || Secretory protein; a-specific, alpha-factor induced; mutation confers hypersensitivity to toxic ergosterol analog; fluconazole-induced; induced during chlamydospore formation in C. albicans and C. dubliniensis || 1 -0.07 -0.09 0.53 1.48 0.57 0.28 -0.31 -0.04 0.09 0.17 -0.68 -0.03 -0.36 -0.89 -0.52 -1.47
7217 || orf19.1250 || || || Ortholog(s) have role in maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) and cytoplasm, nucleolus localization || 1 0.29 -0.01 0.06 0.64 0.11 -0.48 -0.21 -0.12 -0.54 -0.14 -0.28 -0.25 -0.13 -0.84 0.15 -0.68
7218 || orf19.10713 || PAPALPHA || || Putative poly(A) polymerase; PAP is inhibited by parnafungin antifungals; non-sex gene located within the MTLalpha mating-type-like locus || 1 -0.01 0.17 0.25 0.27 0.03 -0.34 0.03 0.12 -0.51 -0.49 -0.11 0.02 -0.36 -0.79 0.09 -0.64
7219 || orf19.6520 || || || Putative allantoate permease; fungal-specific (no human or murine homolog) || 1 -0.19 -0.50 0.60 1.44 -0.13 0.05 -0.34 -0.03 -0.86 -1.05 -0.47 -0.25 -0.78 -0.65 0.09 -1.24
7220 || orf19.547 || || || Ortholog(s) have 5'-flap endonuclease activity, single-stranded DNA 5'-3' exodeoxyribonuclease activity || 1 -0.16 -0.26 0.06 0.58 -0.23 -0.31 0.06 0.01 -0.15 -0.31 0.10 -0.50 0.08 -0.68 0.22 -0.76
7221 || orf19.1106 || || || Protein with Mob2p-dependent hyphal regulation; fluconazole-induced || 1 -0.25 0.09 -0.24 1.69 0.20 -0.15 -0.19 -0.29 0.43 -1.41 -0.14 0.02 0.61 -2.05
7222 || orf19.6834.10 || TAR1 || || Ortholog of S. cerevisiae Tar1p; Transcript Antisense to Ribosomal RNA; encoded within the 25S rRNA gene on the opposite strand; induced by Tbf1 || 1 -0.04 0.26 0.41 1.23 0.18 0.31 -0.04 -0.20 -0.50 -0.96 -0.46 -0.69 0.12 -1.19 -0.39 -1.54
7223 || orf19.7103 || || || Predicted exonuclease; Spider biofilm induced || 1 -0.02 0.20 -0.08 0.30 0.05 0.25 0.26 -0.22 -0.16 -0.45 0.07 -0.20 0.18 -0.54 -0.40 -0.43
7224 || orf19.4220 || || || Predicted pyridoxal 5'-phosphate synthase; regulated by Gcn4; repressed by amino acid starvation (3-AT treatment); rat catheter biofilm repressed || 1 0.26 -0.03 0.28 0.28 0.01 -0.05 -0.12 0.06 -0.16 -0.30 -0.01 -0.20 -0.10 -0.42 -0.16 0.05
7225 || orf19.7206 || OCA6 || || Putative protein phosphatase of the PTP family (tyrosine-specific), similar to S. cerevisiae Oca6p; mutant shows virulence defect || 1 0.50 0.25 0.66 0.63 0.32 -0.14 -0.31 -0.00 0.40 -0.23 -0.04 0.04 0.17 -0.46 -0.03 -0.10
7226 || orf19.3969 || SFL2 || || Transcription factor involved in regulation of morphogenesis; required for filamentous growth, for virulence in RHE model but not in mice; induced upon RHE infection but C. dubliniensis ortholog is not; Spider biofilm induced || 1 0.44 0.39 0.62 0.71 0.56 -0.26 -0.21 -0.15 0.20 -0.60 -0.15 0.02 0.50 -0.58 0.24 -0.26
7227 || orf19.6624 || || || Ortholog(s) have GTPase activator activity and clathrin-coated vesicle, endosome localization || 1 0.20 0.25 0.41 0.44 0.09 0.01 0.05 -0.05 -0.05 -0.47 -0.21 -0.42 0.24 -0.65 0.14 -0.05
7228 || orf19.3449.2 || || || Putative mitochondrial phosphatidylglycerophosphatase (PGP phosphatase); essential for cardiolipin biosynthesis; rat catheter biofilm induced || 1 0.22 0.10 0.24 0.33 0.16 -0.18 -0.24 -0.09 -0.05 -0.32 -0.12 -0.15 0.28 -0.42 0.19 0.07
7229 || orf19.4690 || || || NRAMP metal ion transporter domain-containing protein; induced by nitric oxide independent of Yhb1; flow model biofilm induced; rat catheter biofilm repressed || 1 0.35 0.01 0.64 0.42 0.44 0.23 -0.41 -0.17 0.08 -0.67 -0.22 -0.33 0.38 -0.74 0.45 0.11
7230 || orf19.7184 || || || Ortholog of C. dubliniensis CD36 : Cd36_73640, C. parapsilosis CDC317 : CPAR2_702340, Candida tenuis NRRL Y-1498 : CANTEDRAFT_112965 and Debaryomyces hansenii CBS767 : DEHA2G16566g || 1 0.05 0.15 0.68 0.61 0.24 0.09 -0.59 -0.42 -0.04 -0.38 -0.18 -0.27 0.21 -0.49 0.17 -0.14
7231 || orf19.5534 || || || Protein with a predicted role in mitotic spindle elongation, vesicle-mediated transport; flow model biofilm induced || 1 0.34 0.04 0.31 0.82 0.18 0.30 -0.50 -0.14 -0.14 -0.55 -0.23 0.02 0.01 -0.39 0.13 -0.02
7232 || orf19.6940 || || || Protein of unknown function || 1 0.40 0.16 0.68 1.42 0.33 0.22 -0.62 0.11 -0.26 -0.62 0.27 0.13 -0.40 -1.14 -0.18 -0.19
7233 || orf19.7252 || || || Ortholog of Candida albicans WO-1 : CAWG_00017 || 1 0.26 0.36 0.53 0.96 0.01 -0.11 -0.40 -0.06 -0.22 -0.91 -0.30 0.20 -0.30 -1.03 0.14 -0.14
7234 || orf19.5422 || || || Ortholog of C. dubliniensis CD36 : Cd36_80400, Candida tropicalis MYA-3404 : CTRG_06188 and Candida albicans WO-1 : CAWG_02379 || 1 0.29 0.37 0.52 0.59 0.20 0.17 -0.22 -0.12 0.11 -0.77 -0.06 -0.05 -0.15 -0.88 0.10 0.30
7235 || orf19.5495 || || || Putative RNA-binding protein; induced by alpha pheromone in SpiderM medium || 1 0.61 0.41 0.61 0.64 0.33 -0.14 -0.47 -0.40 -0.59 -0.27 0.43 0.00 0.11 -0.99 0.18 -0.28
7236 || orf19.2082 || SAP30 || || Aspartic-type endopeptidase; involved in degradation of alpha pheromone; functional equivalent of S. cerevisiae Bar1; a-cell specific; induced by alpha pheromone || 1 1.32 1.67 1.78 1.15 0.71 -0.30 -0.51 -0.84 -0.70 -0.57 -0.15 -1.12 0.94 -2.80 -0.96 -1.59
7237 || orf19.1162.1 || || || Ortholog(s) have Golgi apparatus localization || 1 0.25 0.36 0.62 0.37 0.55 0.51 -0.26 -0.40 -0.10 -0.64 -0.25 -0.35 0.42 -1.18 -0.07 -0.15
7238 || orf19.3677 || || || Ortholog(s) have Atg8 ligase activity and role in C-terminal protein lipidation, CVT pathway, ascospore formation, cellular response to nitrogen starvation, macroautophagy, mitochondrion degradation, piecemeal microautophagy of nucleus || 1 0.49 0.51 0.10 0.11 0.43 0.34 -0.06 -0.59 -0.04 -0.55 -0.18 -0.16 0.22 -0.73 -0.09 -0.25
7239 || orf19.763 || || || Small subunit of the heterodimeric cap binding complex; component of the spliceosomal commitment complex; Spider biofilm repressed || 1 0.18 0.28 0.35 0.38 0.41 0.46 -0.34 -0.06 -0.20 -0.09 0.16 -0.21 0.21 -0.39 0.01 -0.17
7240 || orf19.510 || || || Protein of unknown function; Spider biofilm induced || 1 -0.13 0.64 1.01 1.62 1.23 1.02 0.29 0.03 -0.03 0.37 -0.22 -1.32 -0.44 -0.67 0.18 0.08
7241 || orf19.2445 || || || Putative dicarboxylic amino acid permease; fungal-specific (no human or murine homolog); induced by alpha pheromone in SpiderM medium || 1 1.32 0.65 0.80 2.12 0.34 0.67 -0.08 0.05 0.06 0.66 -0.42 -1.30 0.50 -0.18 -0.09 0.14
7242 || orf19.4076 || MET10 || || Sulfite reductase; role in sulfur amino acid metabolism; induced by human whole blood or PMNs; Hog1-induced; possibly adherence-induced; flow model, Spider model, F-12/CO2 biofilm induced || 1 0.44 0.43 1.12 1.51 -0.27 0.70 -0.39 -0.08 -0.08 0.30 -0.39 -0.46 -0.50 -1.29 -0.15 -0.19
7243 || orf19.510 || || || Protein of unknown function; Spider biofilm induced || 1 0.51 1.06 1.27 2.31 0.52 0.83 -0.72 -0.24 -0.12 0.82 -0.58 -1.07 -0.24 -1.15 0.10 -0.61
7244 || orf19.510 || || || Protein of unknown function; Spider biofilm induced || 1 0.54 0.81 1.62 2.56 0.56 1.12 -1.33 -0.69 -0.86 1.28 -0.90 -1.43 -0.21 -1.76 0.10 -1.25
7245 || orf19.510 || || || Protein of unknown function; Spider biofilm induced || 1 0.47 0.38 0.97 2.09 0.36 0.94 -0.54 0.05 -1.30 0.53 -0.95 -1.05 -0.60 -0.48 0.29 -0.51
7246 || orf19.510 || || || Protein of unknown function; Spider biofilm induced || 1 1.50 0.84 1.09 2.10 0.75 0.94 -0.33 0.01 -1.61 0.59 -0.57 -2.22 -0.06 -1.04 0.44 -0.22
7247 || orf19.7650 || LTV1 || || Putative GSE complex component; repressed by prostaglandins || 1 0.30 0.33 0.50 0.56 0.39 0.61 -0.01 0.16 -0.68 0.38 -0.46 -0.64 0.23 -0.54 0.14 -0.45
7248 || orf19.4056 || BRG1 || || Transcription factor; recruits Hda1 to hypha-specific promoters; Tn mutation affects filamentation; Hap43-repressed; Spider and flow model biofilm induced; required for Spider biofilm formation; Bcr1-repressed in RPMI a/a biofilms || 1 0.27 0.61 1.19 1.11 -0.24 -0.34 0.43 -0.43 0.94 0.32 -0.47 -0.02 0.83 0.03 0.76 -1.06
7249 || orf19.3283 || || || Ortholog(s) have 3-oxoacyl-[acyl-carrier-protein] reductase (NADPH) activity, role in aerobic respiration, fatty acid metabolic process and mitochondrion localization || 1 0.33 0.35 0.51 0.58 -0.11 -0.12 -0.08 -0.47 0.74 0.16 -0.35 -0.18 0.19 0.08 -0.04 -0.67
7250 || orf19.7668 || MAL2 || || Alpha-glucosidase; hydrolyzes sucrose for sucrose utilization; transcript regulated by Suc1, induced by maltose, repressed by glucose; Tn mutation affects filamentous growth; upregulated in RHE model; rat catheter and Spider biofilm induced || 1 0.39 0.54 0.14 1.28 -0.32 -0.29 0.47 -0.15 0.61 0.12 -0.25 -0.81 0.14 -0.13 -0.39 -1.03
7251 || orf19.3432 || || || Predicted membrane transporter, member of the drug:proton antiporter (12 spanner) (DHA1) family, major facilitator superfamily (MFS); induced by nitric oxide || 1 0.67 0.75 1.38 1.60 -0.41 -0.08 0.20 -0.28 1.04 -0.59 -0.02 -0.82 0.31 -0.82 0.19 -1.14
7252 || orf19.2810 || AAP1 || || Putative amino acid permease; fungal-specific; possibly essential, disruptants not obtained by UAU1 method; Spider biofilm induced || 1 0.43 0.43 0.54 1.15 0.04 -0.17 0.39 0.32 0.23 -0.20 -0.02 -0.43 0.59 -0.37 0.30 -0.60
7253 || orf19.168 || || || Ortholog(s) have role in U4 snRNA 3'-end processing, exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA and LSU-rRNA), more || 1 0.69 -0.22 0.51 0.90 -0.33 0.62 -0.15 -0.01 0.41 -0.09 -0.79 -0.56 0.00 -0.24 -0.16 -1.12
7254 || orf19.5516 || || || Ortholog(s) have signal sequence binding activity, role in protein targeting to ER and cytosol, nucleus, signal recognition particle, endoplasmic reticulum targeting localization || 1 0.29 -0.07 0.64 0.63 0.02 0.68 -0.13 0.05 0.28 0.32 -0.34 -0.34 -0.05 -0.02 -0.07 -0.77
7255 || orf19.4384 || HXT5 || || Putative sugar transporter; induced by ciclopirox olamine; Snf3-induced; alkaline repressed; colony morphology-related gene regulation by Ssn6; possibly essential gene || 1 0.62 0.38 1.46 1.32 0.02 0.89 0.51 0.64 1.04 0.75 -0.71 -1.10 0.77 -0.05 0.31 -1.06
7256 || orf19.1599 || || || Ortholog of Candida albicans WO-1 : CAWG_06018 || 1 0.38 0.05 0.99 1.39 -0.31 0.54 0.33 0.07 1.69 0.59 -1.08 -1.13 0.78 0.05 -0.55 -1.49
7257 || orf19.2878 || PGA15 || || Putative GPI-anchored protein || 1 0.22 0.11 0.95 0.98 -0.03 0.81 -0.29 -0.20 0.53 0.73 -0.48 -1.02 -0.02 0.13 -0.20 -0.37
7258 || orf19.2285 || || || Protein of unknown function; transcription induced by benomyl treatment || 1 0.10 0.37 1.07 0.74 -0.05 0.44 -0.08 -0.19 0.42 0.07 -0.43 -0.49 -0.12 0.14 -0.21 -0.31
7259 || orf19.1237 || ARO9 || || Aromatic transaminase; Ehrlich fusel oil pathway of aromatic alcohol biosynthesis; Rim101-dependent pH-regulation (alkaline induced); Hap43-induced gene || 1 0.16 0.34 1.00 1.11 0.11 0.57 -0.03 -0.19 0.64 0.05 -0.28 -0.52 0.21 0.12 0.20 0.08
7260 || orf19.6418 || || || Ortholog(s) have role in ribosomal large subunit biogenesis and cytoplasm, nucleus localization || 1 0.39 0.31 0.63 0.73 0.35 1.14 0.04 0.40 0.17 0.55 -0.38 -0.94 0.08 0.31 -0.07 -0.44
7261 || orf19.831 || || || Ortholog of C. dubliniensis CD36 : Cd36_18570, C. parapsilosis CDC317 : CPAR2_211360, Candida tenuis NRRL Y-1498 : CANTEDRAFT_115359 and Debaryomyces hansenii CBS767 : DEHA2D06886g || 1 0.12 0.33 0.35 0.36 0.35 0.46 -0.51 -0.47 -0.07 0.29 -0.30 0.12 0.46 0.09 0.27 -0.54
7262 || orf19.4592 || HSX11 || || UDP-glucose:ceramide glucosyltransferase (glucosylceramide synthase [GCS], EC 2.4.1.80); involved in glucosylceramide biosynthesis, which is important for virulence || 1 0.03 0.19 0.56 0.41 0.51 0.37 -0.35 -0.24 0.21 0.37 -0.40 -0.04 0.35 0.09 0.08 -0.72
7263 || orf19.5548 || LYS14 || || Zn(II)2Cys6 transcription factor; has similarity to S. cerevisiae Lys14, which is a transcription factor involved in the regulation of lysine biosynthesis genes || 1 0.25 0.34 0.67 0.30 0.31 0.38 -0.17 -0.31 -0.04 0.09 -0.58 -0.16 0.29 0.15 0.09 -0.22
7264 || orf19.1350 || || || Protein with a thioredoxin domain; predicted role in cell redox homeostasis; rat catheter and Spider biofilm induced || 1 0.70 0.79 0.98 0.93 0.44 0.21 -0.54 -1.11 -0.37 0.19 -1.15 -0.22 0.86 0.90 0.89 -0.83
7265 || orf19.1350 || || || Protein with a thioredoxin domain; predicted role in cell redox homeostasis; rat catheter and Spider biofilm induced || 1 0.73 0.80 0.96 0.95 0.91 0.20 -0.52 -0.32 0.24 0.08 -0.76 -0.24 0.85 0.51 0.59 -1.03
7266 || orf19.4349 || || || Protein of unknown function; transcript repressed by elevated CO2; Spider biofilm induced || 1 0.22 0.35 0.60 0.43 0.39 0.16 -0.45 -0.47 0.21 -0.02 -0.68 -0.66 0.73 0.29 -0.18 -0.67
7267 || orf19.4274 || PUT1 || || Putative proline oxidase; alkaline upregulated by Rim101; flow model biofilm induced; Spider biofilm induced || 1 1.68 1.62 1.80 1.47 0.68 -0.52 -1.50 -1.65 0.77 0.50 -2.02 -1.30 1.10 0.28 -0.11 -1.17
7268 || orf19.3084 || || || Ortholog(s) have histone acetyltransferase activity, role in chromatin silencing at telomere and SAS acetyltransferase complex, nuclear chromatin localization || 1 0.06 0.32 0.37 0.44 0.53 0.02 -0.30 -0.33 0.31 -0.36 -0.34 -0.38 0.53 0.04 -0.25 0.04
7269 || orf19.6803 || HUT1 || || Ortholog(s) have UDP-galactose transmembrane transporter activity, role in UDP-galactose transmembrane transport, UDP-glucose transport, regulation of protein folding in endoplasmic reticulum and endoplasmic reticulum localization || 1 0.11 0.51 0.38 0.51 0.52 -0.06 -0.26 -0.44 0.31 -0.16 -0.57 0.17 0.54 -0.03 -0.14 0.02
7270 || orf19.5345 || || || Putative ubiquitin-like polyubiquitin-binding protein; induced by nitric oxide independent of Yhb1; Spider biofilm repressed || 1 0.19 0.53 0.61 0.66 0.49 -0.03 -0.51 -0.29 0.12 -0.23 -0.28 0.08 0.48 -0.09 0.04 -0.34
7271 || orf19.5009 || || || Ortholog(s) have cytoplasm localization || 1 -0.15 0.10 0.61 0.44 0.28 0.35 -0.51 -0.56 0.28 0.11 -0.40 -0.15 0.50 -0.18 -0.24 -0.38
7272 || orf19.1259 || || || Ortholog(s) have DNA binding, ubiquitin-protein ligase activity and role in histone catabolic process, histone ubiquitination, regulation of transcription from RNA polymerase II promoter in response to oxidative stress || 1 -0.11 0.05 0.40 0.25 0.05 -0.01 -0.43 -0.44 0.45 -0.52 -0.48 0.20 0.39 -0.25 0.12 -0.88
7273 || orf19.3877 || || || Ortholog of C. dubliniensis CD36 : Cd36_73360 and Candida albicans WO-1 : CAWG_01936 || 1 -0.18 0.15 0.57 0.36 0.41 0.25 -0.43 -0.31 0.31 -0.46 -0.44 0.14 0.44 -0.15 0.13 -0.34
7274 || orf19.6779 || PRO2 || || Putative gamma-glutamyl phosphate reductase with a predicted role in proline biosynthesis; regulated by Gcn2p and Gcn4p || 1 0.15 0.29 0.25 0.56 0.29 0.17 -0.39 -0.44 0.20 -0.12 -0.36 -0.14 0.17 -0.09 0.21 -0.34
7275 || orf19.916 || || || Putative protein involved in apoptosis; Spider biofilm induced || 1 0.07 0.42 0.36 0.66 0.45 0.15 -0.55 -0.71 0.19 -0.40 -0.92 -0.31 0.32 -0.21 0.20 -0.52
7276 || orf19.487 || SPT14 || || Putative DNA-binding transcription factor; predicted role in regulation of biogenesis of the cell wall; upregulated in biofilm; protein newly produced during adaptation to the serum || 1 -0.04 0.31 0.54 0.31 0.21 -0.02 -0.26 -0.39 0.40 -0.35 -0.43 -0.47 0.23 -0.04 -0.26 -0.54
7277 || orf19.6141 || HGT16 || || Putative glucose transporter of the major facilitator superfamily; the C. albicans glucose transporter family comprises 20 members; 12 probable membrane-spanning segments; gene has intron; expressed in rich medium with 2% glucose || 1 -0.25 0.17 0.55 0.87 0.38 -0.05 -0.63 -0.45 0.26 -0.51 -0.65 -0.75 0.52 -0.40 -0.19 -0.54
7278 || orf19.7104 || || || Adhesin-like cell wall protein; similar to mucins and to a Litomosoides microfilarial sheath protein; N-terminal secretion signal; rat catheter and Spider biofilm repressed || 1 -0.17 0.24 0.51 0.36 0.33 -0.24 -0.43 -0.36 -0.10 -0.45 -0.54 -0.24 0.51 -0.21 0.05 -0.51
7279 || orf19.7072 || PEL1 || || Predicted enzyme of mitochondrial phospholipid biosynthesis; rat catheter and flow model biofilm induced || 1 0.04 0.22 0.50 0.37 0.33 0.26 -0.39 -0.31 0.01 -0.58 -0.37 -0.22 0.27 -0.43 0.02 -0.58
7280 || orf19.4551 || CTN1 || || Carnitine acetyl transferase; required for growth on nonfermentable carbon sources, not for hyphal growth or virulence in mice; induced in macrophage; macrophage/pseudohyphal-repressed after 16 hr; rat catheter, Spider biofilm induced || 1 0.09 0.65 0.81 0.68 0.64 0.60 -0.27 -0.50 0.33 -0.23 -0.88 -0.79 0.35 -0.63 -0.07 -1.17
7281 || orf19.5037 || HRQ2 || || Protein of unknown function; mutants are viable; rat catheter and Spider biofilm induced || 1 0.26 0.22 0.79 0.42 0.29 0.19 -0.07 -0.19 0.15 -0.49 -0.55 -0.84 0.24 -0.54 0.05 -0.64
7282 || orf19.3457 || SWD3 || || Ortholog(s) have histone methyltransferase activity (H3-K4 specific) activity, role in chromatin silencing at telomere, histone H3-K4 methylation, telomere maintenance and Set1C/COMPASS complex localization || 1 0.14 0.08 0.63 1.41 -0.22 0.20 -0.00 -0.24 -0.49 -0.18 -0.35 -0.03 -0.08 -0.35 -0.09 -0.26
7283 || orf19.4122 || || || Ortholog(s) have acyl-CoA hydrolase activity, role in fatty acid beta-oxidation and mitochondrion, peroxisome localization || 1 0.20 0.19 0.67 1.06 -0.10 0.26 -0.34 -0.32 -0.50 -0.01 -0.12 -0.06 -0.14 -0.43 -0.25 -0.32
7284 || orf19.4095 || || || Ortholog of C. parapsilosis CDC317 : CPAR2_407020, C. dubliniensis CD36 : Cd36_23460, Debaryomyces hansenii CBS767 : DEHA2B02002g and Pichia stipitis Pignal : PICST_31649 || 1 0.17 0.18 1.02 1.13 0.08 0.52 -0.32 -0.38 0.09 -0.25 -0.71 -0.22 -1.39
7285 || orf19.2922 || || || Ortholog(s) have double-stranded DNA binding activity, role in reciprocal meiotic recombination, synapsis and condensed nuclear chromosome localization || 1 0.79 0.08 1.56 1.34 -0.44 0.53 -0.41 -0.35 -0.39 -0.22 -0.73 -0.63 -0.99 -1.03 -0.26 -1.16
7286 || orf19.3107 || || || Ortholog of C. dubliniensis CD36 : Cd36_46490, Pichia stipitis Pignal : PICST_33598, Spathaspora passalidarum NRRL Y-27907 : spas_CGOB_00037 and Candida tropicalis MYA-3404 : CTRG_03758 || 1 -0.03 -0.17 1.16 1.15 -0.11 0.31 -0.16 -0.29 -0.31 -0.24 -0.67 -0.52 -0.68 -0.66 -0.17 -0.28
7287 || orf19.261 || || || Ortholog(s) have dolichol kinase activity, role in protein glycosylation and endoplasmic reticulum membrane localization || 1 -0.27 -0.01 0.56 0.51 -0.23 0.14 -0.20 -0.16 -0.22 -0.22 -0.40 -0.18 -0.15 -0.79 -0.14 -0.38
7288 || orf19.3286 || || || Ortholog(s) have alpha-glucosidase activity, role in polysaccharide biosynthetic process, protein N-linked glycosylation and endoplasmic reticulum lumen, glucosidase II complex localization || 1 -0.33 0.21 0.34 0.85 -0.34 0.29 -0.62 -0.17 -0.27 -0.21 -0.71 -0.05 -0.82 -0.75 -0.35 -0.38
7289 || orf19.4076 || MET10 || || Sulfite reductase; role in sulfur amino acid metabolism; induced by human whole blood or PMNs; Hog1-induced; possibly adherence-induced; flow model, Spider model, F-12/CO2 biofilm induced || 1 0.67 0.78 0.90 1.40 -0.49 0.16 -0.43 0.04 -0.21 0.35 -0.50 -0.75 -1.61 -1.90 -0.39 -0.76
7290 || orf19.1480 || || || Putative succinate dehydrogenase; enzyme of citric acid cycle; repressed by nitric oxide; Efg1, Hap43 repressed || 1 0.38 0.50 0.61 0.59 -0.23 0.26 -0.29 -0.07 0.17 0.06 -0.45 -0.24 -0.50 -0.69 -0.48 -0.12
7291 || orf19.1480 || || || Putative succinate dehydrogenase; enzyme of citric acid cycle; repressed by nitric oxide; Efg1, Hap43 repressed || 1 0.49 0.53 0.72 0.74 -0.34 0.03 -0.07 0.40 0.27 0.15 -0.33 -0.29 -0.54 -0.84 -0.86 -0.51
7292 || orf19.988 || || || Protein of unknown function; oral infection upregulated gene; upregulated in strains from HIV+ patients with oral candidiasis; mutants have reduced ability to damage oral epithelial cells; transcript possibly regulated upon hyphal formation || 1 0.79 0.50 0.29 1.27 -0.18 0.23 -0.81 -0.42 -0.13 -0.69 -0.34 -0.47 -1.10 -0.39 -0.60 -0.56
7293 || orf19.2008 || || || Ortholog(s) have S-methyl-5-thioribose-1-phosphate isomerase activity, role in L-methionine salvage from methylthioadenosine and cytosol, nucleus localization || 1 1.32 1.15 1.30 1.60 -0.20 0.15 -1.10 -0.71 -0.95 -0.17 -0.56 -0.47 -1.33 -0.45 -1.00 -0.51
7294 || orf19.2008 || || || Ortholog(s) have S-methyl-5-thioribose-1-phosphate isomerase activity, role in L-methionine salvage from methylthioadenosine and cytosol, nucleus localization || 1 1.54 1.53 1.07 2.13 -0.10 0.55 -0.42 -0.59 -0.37 0.31 -0.64 -0.71 -0.96 -0.03 -0.82 -0.66
7295 || orf19.4306 || || || Ortholog(s) have methylthioribulose 1-phosphate dehydratase activity, role in L-methionine salvage from methylthioadenosine and cytoplasm localization || 1 0.93 1.11 0.57 0.65 -0.19 -0.13 -0.28 0.02 -0.56 -0.03 0.02 -0.28 -1.13 -0.50 -0.75 -0.80
7296 || orf19.7611 || TRX1 || || Thioredoxin; involved in response to reactive oxygen species; biofilm, benomyl, flucytosine, peroxide, Hap43 induced; amphotericin B, caspofungin repressed; induced by human neutrophils; macrophage-repressed gene || 1 0.58 0.60 0.05 -0.22 -0.20 -0.25 -0.14 0.16 -0.38 0.11 -0.43 -0.20
7297 || orf19.192 || || || Ortholog of C. dubliniensis CD36 : Cd36_19320, C. parapsilosis CDC317 : CPAR2_209670, Candida tenuis NRRL Y-1498 : CANTEDRAFT_113478 and Debaryomyces hansenii CBS767 : DEHA2C15136g || 1 0.69 0.44 0.95 0.89 0.12 -0.24 -0.57 -0.46 -0.20 0.00 -0.36 -0.18 0.01 0.65 -0.58 -0.30
7298 || orf19.3516 || || || Protein of unknown function; Hap43-repressed; Spider biofilm repressed || 1 0.39 0.31 0.96 0.67 -0.43 -0.63 -0.42 -0.19 -0.26 0.05 -0.54 -0.30 -0.20 0.23 -0.47 -0.15
7299 || orf19.7500 || PXA1 || || Putative peroxisomal, half-size adrenoleukodystrophy protein (ALD or ALDp) subfamily ABC family transporter || 1 0.70 0.66 0.93 1.08 -0.17 -0.83 -0.65 -0.33 -0.18 0.29 -0.77 -0.22 0.08 -0.07 -0.48 -0.32
7300 || orf19.7304 || || || Protein of unknown function; Hap43-induced; transcript induced early in infection of reconstituted human epithelium, while expression of the C. dubliniensis ortholog is not upregulated; mutants are viable; rat catheter biofilm repressed || 1 0.16 0.18 0.69 1.05 0.04 -0.36 -0.31 -0.22 -0.25 0.15 -0.51 -0.16 -0.17 0.08 -0.39 -0.32
7301 || orf19.3407 || RAD18 || || Putative transcription factor with zinc finger DNA-binding motif; Hap43p-repressed gene || 1 0.17 0.03 0.76 0.67 -0.17 0.04 -0.28 -0.28 -0.31 -0.28 -0.36 -0.04 0.08 -0.48 0.07 0.06
7302 || orf19.6023 || || || Protein with a predicted multidrug transporter domain; Hap43-repressed gene || 1 0.78 0.71 1.19 1.22 -0.34 -0.15 -0.58 -0.66 -0.37 -0.73 -1.14 -0.34 -0.25 -0.56 -0.49 0.42
7303 || orf19.1124 || || || Protein of unknown function; flow model biofilm induced; Spider biofilm induced || 1 0.54 0.37 1.09 1.51 0.11 -0.22 -0.72 -0.47 -0.28 -0.67 -1.12 0.30 -0.21 -0.71 -0.33 -0.47
7304 || orf19.5027 || LCB2 || || Putative serine palmitoyltransferase component; mutation confers hypersensitivity to aureobasidin A || 1 0.38 0.27 0.28 0.74 0.04 -0.18 -0.32 -0.06 -0.10 -0.14 -0.19 -0.08 -0.00 -0.35 -0.14 -0.14
7305 || orf19.3904 || MRV4 || || Protein of unknown function; Spider biofilm induced || 1 0.86 0.79 0.40 0.89 0.25 -0.68 -0.48 -0.55 -0.22 -0.65 -0.78 -0.37 0.14 -0.66 -0.51 -0.21
7306 || orf19.6520 || || || Putative allantoate permease; fungal-specific (no human or murine homolog) || 1 0.64 1.44 0.66 1.88 0.45 -0.64 -0.83 -0.99 -0.90 -0.39 -1.02 -0.89 -0.44 -1.01 0.07 -0.75
7307 || orf19.94 || || || Protein of unknown function; Spider biofilm induced || 1 0.10 0.23 0.77 1.21 0.46 -0.02 -0.47 -0.19 -0.10 -0.12 -0.87 -0.69 -0.11 -0.34 0.19 -1.05
7308 || orf19.3418 || || || Ortholog(s) have endoplasmic reticulum, fungal-type vacuole localization || 1 0.50 0.30 1.70 1.66 -0.25 0.20 -0.11 0.00 0.25 -0.31 -0.64 -1.90 -0.09 -0.10 -0.54 -1.50
7309 || orf19.4509 || || || Protein of unknown function || 1 0.21 -0.01 1.28 0.88 -0.19 0.53 -0.33 -0.59 0.13 -0.56 -0.69 -1.25 -0.40 -0.38 -0.88 -2.07
7310 || orf19.6192 || || || Protein of unknown function; Plc1-regulated; transcript detected in high-resolution tiling arrays || 1 0.16 0.76 1.41 1.15 -0.41 0.12 -0.42 -0.68 -0.47 -0.56 -0.50 -1.07 -0.04 -0.03 -0.70 -1.91
7311 || orf19.943 || FET33 || || Putative multicopper ferro-O2-oxidoreductase; repressed in core caspofungin response; fails to complement S. cerevisiae fet3 iron-related phenotypes; rat catheter and Spider biofilm induced || 1 0.03 0.25 0.92 0.41 -0.03 -0.12 -0.31 -0.35 -0.04 -0.05 -0.54 -0.32 -0.02 -0.25 -0.17 -0.39
7312 || orf19.5940 || ZCF32 || || Predicted Zn(II)2Cys6 transcription factor; possibly an essential gene, disruptants not obtained by UAU1 method; Hap43-repressed || 1 0.57 0.46 0.57 0.74 -0.24 0.17 -0.26 -0.56 -0.02 -0.41 -0.74 0.02 -0.28 -0.00 -0.20 -0.64
7313 || orf19.1523 || FMO1 || || Putative oxidoreductase; mutation confers hypersensitivity to toxic ergosterol analog, and to amphotericin B || 1 0.09 0.09 0.74 1.38 -0.41 -0.09 0.03 -0.24 -0.40 -0.68 -1.15 -0.87 -0.36 -0.25 -0.36 -0.43
7314 || orf19.164 || || || Ortholog(s) have lipase activity and peroxisomal matrix localization || 1 0.32 0.29 1.13 1.52 -0.93 -0.09 -0.62 -0.44 -0.46 -0.06 -1.58 -1.28 -0.26 -0.04 -1.08 -0.71
7315 || orf19.164 || || || Ortholog(s) have lipase activity and peroxisomal matrix localization || 1 0.15 0.27 0.75 1.42 -1.40 -0.36 -0.80 -0.56 -0.39 -0.22 -2.00 -1.39 -0.75 -0.14 -1.09 -0.55
7316 || orf19.3874 || || || Predicted cation transmembrane transporter; Spider biofilm induced || 1 0.34 0.40 0.52 0.82 -1.04 -0.56 -0.35 -0.48 -0.17 0.42 -1.62 -0.95 -0.21 0.03 -0.45 -1.00
7317 || orf19.6844 || ICL1 || || Isocitrate lyase; glyoxylate cycle enzyme; required for virulence in mice; induced upon phagocytosis by macrophage; farnesol regulated; Pex5-dependent peroxisomal localization; stationary phase enriched; rat catheter, Spider biofilm induced || 1 1.33 1.47 1.17 1.98 -2.18 -1.42 -0.28 -1.92 -0.25 0.10 -3.53 -2.01 -1.31 -0.51 -0.15 -2.35
7318 || orf19.4833 || MLS1 || || Malate synthase; glyoxylate cycle enzyme; no mammalian homolog; regulated upon white-opaque switch; phagocytosis, strong oxidative stress induced; stationary phase enriched; flow model biofilm repressed; rat catheter, Spider biofilm induced || 1 1.24 1.26 0.84 1.32 -1.19 -0.56 -0.21 -0.94 0.16 -0.40 -2.37 -0.49 -0.45 -0.06 -0.03 -1.01
7319 || orf19.4833 || MLS1 || || Malate synthase; glyoxylate cycle enzyme; no mammalian homolog; regulated upon white-opaque switch; phagocytosis, strong oxidative stress induced; stationary phase enriched; flow model biofilm repressed; rat catheter, Spider biofilm induced || 1 1.12 1.12 1.03 1.29 -1.30 -0.64 -0.10 -0.78 0.12 -0.43 -2.41 -0.43 -0.35 -0.45 -0.46 -1.05
7320 || orf19.113 || CIP1 || || Possible oxidoreductase; transcript induced by cadmium but not other heavy metals, heat shock, yeast-hypha switch, oxidative stress (via Cap1), or macrophage interaction; stationary phase enriched protein; Spider biofilm induced || 1 0.42 0.63 0.83 1.12 -0.74 0.20 -0.67 -0.50 0.14 -0.19 -1.48 -0.53 -0.54 -0.74 -0.13 -0.68
7321 || orf19.499 || || || Ortholog(s) have S-adenosylmethionine-dependent methyltransferase activity, role in translational readthrough and mitochondrion localization || 1 0.48 0.45 0.73 0.98 -0.37 -0.09 -0.45 -0.54 0.05 -0.12 -1.15 -0.58 -0.41 -0.18 -0.08 -0.48
7322 || orf19.7520 || POT1 || || Putative peroxisomal 3-oxoacyl CoA thiolase; transcript regulated by Nrg1 and Mig1; farnesol regulated; Hap43-repressed || 1 0.68 0.70 1.56 1.96 -0.25 -0.33 -0.65 -0.59 -0.34 -0.08 -1.43 -0.72 -0.71 -0.69 -0.35 -1.19
7323 || orf19.7481 || MDH1 || || Mitochondrial malate dehydrogenase; regulated by Mig1, Tup1, white-opaque switch, phagocytosis; induced in high iron; antigenic during murine and human infection; repressed in Spider biofilms by Bcr1, Tec1, Ndt80, Rob1, Brg1 || 1 0.66 0.69 1.43 1.85 -0.72 -0.51 -0.58 -0.45 -0.36 -0.36 -1.34 -0.64 -0.84 -0.30 -0.08 -0.96
7324 || orf19.7481 || MDH1 || || Mitochondrial malate dehydrogenase; regulated by Mig1, Tup1, white-opaque switch, phagocytosis; induced in high iron; antigenic during murine and human infection; repressed in Spider biofilms by Bcr1, Tec1, Ndt80, Rob1, Brg1 || 1 0.46 0.53 1.29 1.44 -0.77 -0.66 -0.45 -0.45 -0.49 -0.29 -1.31 -0.82 -0.88 -0.34 -0.28 -1.09
7325 || orf19.7481 || MDH1 || || Mitochondrial malate dehydrogenase; regulated by Mig1, Tup1, white-opaque switch, phagocytosis; induced in high iron; antigenic during murine and human infection; repressed in Spider biofilms by Bcr1, Tec1, Ndt80, Rob1, Brg1 || 1 0.43 0.44 0.89 1.40 -0.90 -0.78 -0.57 -0.50 -0.32 -0.56 -1.20 -0.76 -0.64 -0.36 -0.33 -1.03
7326 || orf19.6376 || PTC5 || || Mitochondrial protein phosphatase of the Type 2C-related family (serine/threonine-specific), involved in drug response and cadmium tolerance || 1 0.51 0.39 0.70 0.85 0.16 -0.05 -0.67 -0.79 0.12 -0.20 -0.94 -0.36 -0.03 -0.19 -0.43 -0.27
7327 || orf19.5215 || TES15 || || Putative acyl-CoA thioesterase; Hap43-repressed; Spider biofilm induced || 1 -0.03 -0.02 0.86 0.80 -0.36 -0.12 -0.30 -0.32 0.14 -0.06 -0.82 -0.37 0.00 -0.53 -0.28 -0.81
7328 || orf19.5215 || TES15 || || Putative acyl-CoA thioesterase; Hap43-repressed; Spider biofilm induced || 1 0.11 0.13 0.75 0.89 -0.03 -0.25 -0.58 -0.71 0.38 -0.06 -1.56 -1.03 -0.03 -0.68 -0.28 -0.76
7329 || orf19.1596 || FGR28 || || Protein lacking an ortholog in S. cerevisiae; transposon mutation affects filamentous growth; possibly an essential gene, disruptants not obtained by UAU1 method || 1 0.12 0.03 0.48 0.73 -0.01 -0.15 -0.26 -0.56 0.31 -0.13 -0.77 -0.32 0.01 -0.23 -0.22 -0.40
7330 || orf19.3684 || || || Putative oxidoreductase; Spider biofilm induced || 1 -0.20 0.07 1.07 1.09 0.02 0.18 -0.66 -0.68 0.29 -0.14 -0.95 -0.87 0.39 -0.38 -0.55 -0.83
7331 || orf19.7071 || FGR2 || || Protein similar to phosphate transporters; transposon mutation affects filamentous growth; expression is regulated upon white-opaque switching || 1 0.37 0.37 1.63 1.87 0.06 0.41 -0.55 -0.77 0.04 0.43 -1.68 -2.23 0.49 -0.88 -1.02 -1.40
7332 || orf19.3684 || || || Putative oxidoreductase; Spider biofilm induced || 1 0.52 0.62 1.89 2.20 -0.25 -0.94 -1.07 -0.63 -0.13 0.23 -2.24 -1.57 0.96 -0.49 -1.52 -1.92
7333 || orf19.4174 || || || Ortholog(s) have nicotinamide riboside transmembrane transporter activity, role in nicotinamide riboside transport, transmembrane transport and fungal-type vacuole membrane localization || 1 0.13 0.15 0.81 0.83 -0.16 -0.38 -0.45 -0.41 0.19 -0.42 -0.97 -0.94 0.11 -0.06 -0.70 -0.62
7334 || orf19.3684 || || || Putative oxidoreductase; Spider biofilm induced || 1 0.81 0.46 1.92 2.20 -0.73 -0.53 -0.64 -0.67 -0.26 0.32 -1.50 -1.26 0.75 -0.33 -0.88 -0.55
7335 || orf19.5024 || GND1 || || 6-phosphogluconate dehydrogenase; soluble in hyphae; farnesol, macrophage-induced protein; antigenic in mice; dual localization to cytosol and peroxisomes depends on alternative splicing; rat catheter and Spider biofilm repressed || 1 0.23 0.23 0.75 0.99 -0.47 -0.24 -0.59 -0.52 -0.27 -0.45 -0.67 -0.44 0.42 -0.09 -0.79 -0.61
7336 || orf19.334 || || || Protein of unknown function; flow model biofilm induced; Spider biofilm induced; regulated by Sef1, Sfu1, and Hap43 || 1 1.68 1.53 1.87 2.18 -2.03 -0.34 -2.04 -2.91 0.18 -1.57 -3.31 -1.63 0.24 -0.62 -1.60 -1.41
7337 || orf19.334 || || || Protein of unknown function; flow model biofilm induced; Spider biofilm induced; regulated by Sef1, Sfu1, and Hap43 || 1 1.87 1.92 1.69 2.06 -1.64 -0.42 -1.82 -2.57 -0.18 -1.61 -3.01 -1.92 0.69 -1.16 -1.25 -1.54
7338 || orf19.6021 || IHD2 || || Protein of unknown function; induced during hyphae development; induced in low iron; Spider biofilm induced || 1 0.41 0.27 0.33 0.78 -0.30 -0.38 -0.58 -0.96 -0.04 -0.26 -1.35 -1.05 0.42 -0.19 -0.32 -0.98
7339 || orf19.6021 || IHD2 || || Protein of unknown function; induced during hyphae development; induced in low iron; Spider biofilm induced || 1 0.53 0.39 0.42 0.71 -0.35 -0.30 -0.31 -0.60 -0.17 -0.07 -1.38 -0.88 0.54 -0.00 -0.04 -1.16
7340 || orf19.4845 || TVP18 || || Putative integral membrane protein; fluconazole-induced || 1 0.86 0.88 0.69 1.10 -0.50 -0.41 -0.79 -0.65 -0.23 -0.08 -1.30 -0.75 0.44 0.02 -0.52 -1.01
7341 || orf19.3415 || PTK2 || || Putative protein kinase of polyamine import; mutation confers hypersensitivity to high concentrations of tunicamycin; YPD flow model biofilm induced; rat catheter and Spider biofilm induced || 1 0.62 0.59 0.81 0.83 -0.46 -0.14 -0.08 -0.89 -0.54 -0.24 -1.01 -0.73 0.13 -0.10 -0.46 -0.93
7342 || orf19.3415 || PTK2 || || Putative protein kinase of polyamine import; mutation confers hypersensitivity to high concentrations of tunicamycin; YPD flow model biofilm induced; rat catheter and Spider biofilm induced || 1 1.16 1.09 1.20 1.07 -0.63 -0.33 -0.08 -1.13 -0.54 -0.36 -1.17 -1.19 0.44 -0.22 -0.86 -1.17
7343 || orf19.6127 || LPD1 || || Putative dihydrolipoamide dehydrogenase; soluble in hyphae; antigenic in human oral infection and murine systemic infection; macrophage-induced protein; protein present in exponential and stationary phase yeast cultures; Hap43p-repressed || 1 0.54 0.49 0.21 0.43 -0.35 0.01 -0.10 -0.25 -0.34 -0.16 -0.78 -0.77 0.15 -0.20 -0.52 -0.71
7344 || orf19.4584 || PHO114 || || Acid phosphatase; induced by Mnl1 under weak acid stress; Spider biofilm induced || 1 1.34 1.35 1.99 2.11 -0.52 0.53 -1.37 -1.34 -0.45 -0.68 -2.70 -1.81 1.04 0.46 -1.86 -2.12
7345 || orf19.4584 || PHO114 || || Acid phosphatase; induced by Mnl1 under weak acid stress; Spider biofilm induced || 1 1.36 1.11 1.76 1.96 -0.30 0.58 -0.69 -0.73 -0.70 -1.03 -1.85 -1.78 0.83 0.17 -0.93 -1.28
7346 || orf19.204 || || || Ortholog of C. dubliniensis CD36 : Cd36_23180, Candida tropicalis MYA-3404 : CTRG_01968 and Candida albicans WO-1 : CAWG_05983 || 1 0.65 0.26 1.09 1.21 -0.12 0.55 -0.63 -0.53 -0.25 -0.50 -1.23 -0.48 0.38 -0.17 -0.39 -0.53
7347 || orf19.3149 || LSP1 || || Eisosome component with a predicted role in endocytosis; protein present in exponential and stationary growth phase yeast cultures; caspofungin repressed; biofilm induced; fungal-specific (no human/murine homolog); sumoylation target || 1 0.28 0.24 0.71 0.86 -0.63 0.22 -0.25 -0.46 -0.19 -0.45 -0.63 -0.40 0.26 -0.22 -0.19 -0.36
7348 || orf19.7077 || || || Putative ferric reductase; induced by Mac1 under copper starvation; Plc1-regulated; Rim101-repressed || 1 1.05 1.03 1.89 2.18 -1.97 0.46 0.22 -1.53 -0.78 -1.42 -2.96 -2.45 0.36 -0.67 -0.80 -1.18
7349 || orf19.4654 || || || Protein of unknown function; Spider biofilm induced || 1 1.17 1.38 2.07 1.99 -0.02 -0.50 -0.84 -1.06 -0.18 -0.46 -1.34 -0.79 0.67 -0.12 -0.65 -0.32
7350 || orf19.4654 || || || Protein of unknown function; Spider biofilm induced || 1 1.15 1.55 2.04 1.99 0.11 -0.78 -1.10 -0.81 -0.81 -0.45 -1.12 -1.24 0.64 -0.01 -0.69 -1.14
7351 || orf19.4654 || || || Protein of unknown function; Spider biofilm induced || 1 1.22 1.48 1.63 1.49 -0.14 -0.66 -0.56 -0.74 -0.25 -0.38 -1.21 -1.01 0.84 0.09 -0.41 -1.14
7352 || orf19.4654 || || || Protein of unknown function; Spider biofilm induced || 1 1.24 1.38 2.01 1.52 -0.02 -0.25 -1.02 -0.52 0.19 -0.07 -1.43 -0.66 0.60 -0.33 -0.48 -1.10
7353 || orf19.5975 || TRY4 || || C2H2 transcription factor; fluconazole-repressed; induced in ssr1 mutant; required for yeast cell adherence to silicone substrate; Spider biofilm induced || 1 1.42 1.35 1.70 2.20 -0.51 -0.88 -0.51 -0.14 -0.76 -0.34 -1.16 -0.80 0.47 0.05 -1.60
7354 || orf19.3226 || || || Ortholog(s) have role in intracellular sterol transport and extracellular region, fungal-type vacuole lumen localization || 1 0.80 0.64 0.69 1.19 -0.57 -0.28 -0.80 -0.40 -0.54 -0.08 -0.68 -0.34 0.56 0.10 0.21 -0.66
7355 || orf19.183 || HIS3 || || Imidazoleglycerol-phosphate dehydratase, enzyme of histidine biosynthesis; functionally complements S. cerevisiae his3-1 mutation; hyphal-induced expression; regulated by Gcn2p and Gcn4p; fungal-specific (no human or murine homolog) || 1 0.66 0.66 0.72 0.76 -0.38 -0.21 -0.36 -0.41 0.18 -0.08 -0.60 -0.39 0.46 -0.07 0.32 -0.67
7356 || orf19.1361 || TIM23 || || Protein involved in mitochondrial matrix protein import || 1 0.58 0.57 0.73 -0.23 0.03 -0.60 -0.68 -0.09 -0.03 -0.87 -0.34 0.31 -0.13 0.68 -0.52
7357 || orf19.6322 || ARD || || D-arabitol dehydrogenase, NAD-dependent (ArDH); enzyme of D-arabitol and D-arabinose catabolism; D-arabitol is a marker for active infection in humans; rat catheter and Spider biofilm induced || 1 1.58 1.55 1.12 1.03 -0.24 0.14 -0.88 -1.15 -0.82 -0.58 -1.88 -2.30 -0.79 -0.65 -0.10 -1.35
7358 || orf19.6322 || ARD || || D-arabitol dehydrogenase, NAD-dependent (ArDH); enzyme of D-arabitol and D-arabinose catabolism; D-arabitol is a marker for active infection in humans; rat catheter and Spider biofilm induced || 1 1.65 1.76 1.57 1.59 -0.07 0.45 -0.76 -1.01 -0.49 -0.40 -1.50 -2.12 -0.52 -0.27 -0.09 -1.54
7359 || orf19.6869 || || || Putative lipid raft associated protein; Spider biofilm induced || 1 1.57 1.45 2.01 1.22 0.91 0.93 -0.39 -0.05 0.56 -0.44 -1.59 -1.04 -0.53 -0.30 -0.24 -1.49
7360 || orf19.5925 || || || Ortholog of S. cerevisiae : AIM6, C. glabrata CBS138 : CAGL0C05533g, C. dubliniensis CD36 : Cd36_84610, C. parapsilosis CDC317 : CPAR2_404550 and Candida tenuis NRRL Y-1498 : CANTEDRAFT_115337 || 1 2.10 1.83 2.24 2.38 0.16 0.75 -0.20 -1.23 -0.72 -0.24 -0.72 -1.36 -0.58 -1.17 -0.52 -2.33
7361 || orf19.4355 || || || Ortholog of C. dubliniensis CD36 : Cd36_29080, C. parapsilosis CDC317 : CPAR2_202490, Candida tenuis NRRL Y-1498 : CANTEDRAFT_112323 and Debaryomyces hansenii CBS767 : DEHA2F19184g || 1 1.91 2.03 2.64 2.63 0.36 0.28 0.13 -0.99 -0.21 -1.27 -0.67 -1.80 0.66 -1.23 -0.74 -2.49
7362 || orf19.7200 || || || Ortholog of C. dubliniensis CD36 : Cd36_73480, Pichia stipitis Pignal : PICST_30727, Candida tropicalis MYA-3404 : CTRG_05165 and Candida albicans WO-1 : CAWG_05712 || 1 1.98 1.63 2.20 1.76 0.25 0.50 -0.41 -0.35 -0.62 -1.22 -1.02 -1.48 0.39 -0.50 -0.59 -1.60
7363 || orf19.5203 || || || Protein of unknown function; Hap43-induced gene || 1 1.39 1.11 1.12 1.98 0.49 0.27 -0.11 0.20 -0.79 0.34 -1.14 -1.87 0.14 -0.22 0.11 -1.15
7364 || orf19.5203 || || || Protein of unknown function; Hap43-induced gene || 1 1.04 0.68 1.16 2.10 0.10 0.50 -0.24 0.09 -0.06 0.21 -1.11 -1.58 -0.26 -0.03 -0.08 -1.06
7365 || orf19.6548 || ISU1 || || Protein with similarity to NifU; possible role in iron-sulfur cluster biogenesis; induced in low iron; rat catheter biofilm induced; rat catheter and Spider biofilm induced || 1 0.68 0.72 0.91 1.35 0.16 0.00 -0.10 -0.45 -0.37 0.15 -0.92 -0.93 -0.26 -0.10 -0.23 -0.93
7366 || orf19.6548 || ISU1 || || Protein with similarity to NifU; possible role in iron-sulfur cluster biogenesis; induced in low iron; rat catheter biofilm induced; rat catheter and Spider biofilm induced || 1 0.75 0.84 0.78 1.30 0.10 -0.13 -0.20 -0.50 -0.37 0.10 -0.97 -1.25 -0.13 -0.28 -0.24 -1.04
7367 || orf19.740 || HAP41 || || Putative Hap4-like transcription factor; Hap43-repressed; not required for response to low iron; induced by Mnl1 under weak acid stress; Spider biofilm induced || 1 0.93 0.92 1.17 1.82 -0.31 0.38 -0.28 -0.69 -0.02 0.13 -1.16 -1.73 -0.73 -0.87 -0.49 -1.88
7368 || orf19.740 || HAP41 || || Putative Hap4-like transcription factor; Hap43-repressed; not required for response to low iron; induced by Mnl1 under weak acid stress; Spider biofilm induced || 1 1.29 1.74 1.37 1.85 0.05 0.54 -0.07 -0.51 -0.25 0.11 -1.65 -1.70 -0.79 -0.85 -0.40 -1.87
7369 || orf19.5141 || || || Ortholog of Candida albicans WO-1 : CAWG_05647 || 1 1.37 1.40 2.14 2.39 0.58 1.43 -0.36 -0.57 -0.20 -0.06 -2.29 -3.13 -0.58 -0.77 -1.25 -2.54
7370 || orf19.5141 || || || Ortholog of Candida albicans WO-1 : CAWG_05647 || 1 0.81 0.90 1.78 2.04 0.31 0.81 -0.07 -0.42 -0.40 -0.13 -1.09 -1.57 -0.42 -0.79 -0.56 -1.20
7371 || orf19.3936 || GDE1 || || Glycerophosphocholine phosphodiesterase; mutation confers hypersensitivity to 5-fluorouracil (5-FU); F-12/CO2 early biofilm induced || 1 0.85 0.46 0.95 0.96 0.19 0.77 0.17 -0.03 0.29 -0.28 -1.13 -1.29 0.03 0.12 -0.53 -1.26
7372 || orf19.3925 || || || Putative protein of unknown function, transcription is activated in the presence of elevated CO2 || 1 0.83 0.61 0.85 1.09 -0.00 1.00 -0.19 -0.03 -0.14 -0.34 -1.19 -0.84 -0.35 0.04 -0.52 -1.14
7373 || orf19.3483 || || || Putative phosphatidyl glycerol phospholipase C; Plc1-regulated; flow model biofilm induced; Spider biofilm induced || 1 1.55 1.37 1.09 1.49 0.79 1.90 -0.29 -0.71 -0.26 -0.77 -2.04 -2.27 -0.21 -0.70 -1.70 -2.72
7374 || orf19.3483 || || || Putative phosphatidyl glycerol phospholipase C; Plc1-regulated; flow model biofilm induced; Spider biofilm induced || 1 1.36 1.28 1.08 1.31 0.83 1.72 -0.22 -0.90 -0.27 -0.56 -1.98 -1.56 -0.04 -0.64 -1.42 -2.23
7375 || orf19.3483 || || || Putative phosphatidyl glycerol phospholipase C; Plc1-regulated; flow model biofilm induced; Spider biofilm induced || 1 0.85 1.07 1.19 1.35 0.88 1.34 -0.35 -0.70 0.19 -0.76 -1.30 -1.25 0.62 -0.29 -0.69 -1.24
7376 || orf19.3483 || || || Putative phosphatidyl glycerol phospholipase C; Plc1-regulated; flow model biofilm induced; Spider biofilm induced || 1 1.05 0.77 1.19 1.50 0.58 1.34 -0.10 -0.41 -0.05 -0.79 -0.98 -0.99 0.33 -0.69 -0.56 -1.02
7377 || orf19.7442 || || || Ortholog of C. dubliniensis CD36 : Cd36_86500, C. parapsilosis CDC317 : CPAR2_206120, Candida tenuis NRRL Y-1498 : CANTEDRAFT_100862 and Debaryomyces hansenii CBS767 : DEHA2F17270g || 1 0.65 0.82 1.17 1.11 0.56 0.84 -0.26 -0.23 -0.10 -0.25 -0.56 -0.59 0.27 -0.25 -0.37 -0.65
7378 || orf19.1943 || || || Ortholog of C. parapsilosis CDC317 : CPAR2_302610, C. dubliniensis CD36 : Cd36_51070, Candida orthopsilosis Co 90-125 : CORT_0E04770 and Spathaspora passalidarum NRRL Y-27907 : SPAPADRAFT_50634 || 1 0.61 0.74 1.05 1.75 1.20 0.76 -0.17 -0.71 -0.16 -0.73 -1.18 -0.91 -0.01 -0.55 0.24 -2.17
7379 || orf19.1943 || || || Ortholog of C. parapsilosis CDC317 : CPAR2_302610, C. dubliniensis CD36 : Cd36_51070, Candida orthopsilosis Co 90-125 : CORT_0E04770 and Spathaspora passalidarum NRRL Y-27907 : SPAPADRAFT_50634 || 1 0.24 0.66 1.22 1.30 0.83 1.46 -0.25 -0.74 -0.16 -0.76 -1.80 -0.86 -0.19 -0.65 -0.08 -2.07
7380 || orf19.4979 || KNS1 || || Protein kinase involved in negative regulation of PolIII transcription; effector kinase of the TOR signaling pathway, phosphorylates Rpc53p to regulate ribosome and tRNA biosynthesis; Spider and flow model biofilm induced || 1 0.77 0.75 1.36 1.58 0.83 1.26 -0.44 -0.56 -0.32 -1.11 -1.56 -1.40 -0.13 -0.49 0.09 -1.42
7381 || orf19.1523 || FMO1 || || Putative oxidoreductase; mutation confers hypersensitivity to toxic ergosterol analog, and to amphotericin B || 1 0.76 0.69 1.04 1.32 0.23 1.07 -0.34 -1.44 -0.44 -0.82 -1.32 -0.99 -0.72 -0.01 -1.81
7382 || orf19.93 || || || Putative mitochondrial intermembrane space protein; colony morphology-related gene regulation by Ssn6; regulated by Sef1, Sfu1, and Hap43; Spider biofilm repressed; rat catheter biofilm induced || 1 0.78 0.99 1.18 1.50 0.65 0.75 -0.47 -0.56 -0.06 -0.30 -0.89 -0.90 0.14 -1.05 -0.11 -1.07
7383 || orf19.6311 || || || Protein of unknown function; Hap43-induced; rat catheter and Spider biofilm induced || 1 2.67 2.85 2.50 2.58 1.60 1.37 -1.36 -1.88 -0.18 -0.22 -2.27 -2.64 -0.32 -1.37 -0.19 -2.60
7384 || orf19.6311 || || || Protein of unknown function; Hap43-induced; rat catheter and Spider biofilm induced || 1 2.87 2.84 2.68 2.71 1.38 1.65 -0.96 -1.67 0.19 0.22 -2.14 -2.39 -0.08 -1.75 0.45 -2.36
7385 || orf19.7504 || || || Ortholog of S. cerevisiae Rts3; a component of the protein phosphatase type 2A complex; Plc1-regulated; induced in core caspofungin response; Spider biofilm induced || 1 1.76 1.75 1.64 1.88 1.76 2.05 -0.80 -1.12 -0.41 0.16 -2.00 -1.70 0.14 -1.01 0.50 -2.03
7386 || orf19.7504 || || || Ortholog of S. cerevisiae Rts3; a component of the protein phosphatase type 2A complex; Plc1-regulated; induced in core caspofungin response; Spider biofilm induced || 1 1.00 0.97 1.64 1.64 0.98 1.65 -0.99 -1.46 -0.27 0.42 -2.90 -1.96 -0.21 -0.95 -0.29 -2.02
7387 || orf19.696 || STE2 || || Receptor for alpha factor mating pheromone, MFalpha; required for a-type cells to respond to alpha factor, for opaque a-form mating and white a-form response; possible Kex2p substrate; a-specific, alpha-factor induced, A1p-Alpha2p repressed || 1 0.93 0.73 1.02 1.01 0.26 1.11 -1.08 -1.32 -0.33 -0.85 -1.52 -0.51 -0.51 -1.23 -0.14 -0.19
7388 || orf19.696 || STE2 || || Receptor for alpha factor mating pheromone, MFalpha; required for a-type cells to respond to alpha factor, for opaque a-form mating and white a-form response; possible Kex2p substrate; a-specific, alpha-factor induced, A1p-Alpha2p repressed || 1 0.85 0.63 1.25 1.28 0.17 1.09 -1.01 -0.90 -0.25 -0.76 -1.33 -0.34 -0.45 -0.96 -0.12 -0.16
7389 || orf19.696 || STE2 || || Receptor for alpha factor mating pheromone, MFalpha; required for a-type cells to respond to alpha factor, for opaque a-form mating and white a-form response; possible Kex2p substrate; a-specific, alpha-factor induced, A1p-Alpha2p repressed || 1 0.91 0.70 1.31 1.36 0.23 1.00 -0.97 -1.25 -0.07 -0.65 -1.48 -0.48 -0.54 -1.01 -0.14 -0.52
7390 || orf19.6654 || || || Predicted membrane transporter, member of the L-amino acid transporter-3 (LAT3) family, major facilitator superfamily (MFS) || 1 0.45 0.27 1.38 1.09 0.18 0.67 -0.29 -0.84 -0.10 -0.52 -0.84 -0.18 -0.46 -0.67 -0.34 -0.35
7391 || orf19.4368 || || || Has domain(s) with predicted hydrolase activity and role in cellular process || 1 0.80 0.58 1.63 1.67 0.88 0.71 -0.38 -0.65 -0.24 -1.00 -1.01 -0.79 0.07 -0.50 -0.15 -0.51
7392 || orf19.7475 || PHO81 || || Protein involved in regulation of hyphal development; required for response to farnesoic acid; possibly adherence-induced || 1 1.65 1.79 1.85 1.82 0.71 1.05 -0.95 -1.18 -0.52 -0.95 -1.36 -0.45 -0.82 -1.19 -1.01 -0.80
7393 || orf19.1042 || POR1 || || Mitochondrial outer membrane porin; in detergent-resistant membrane fraction (possible lipid raft component); antigenic in human, mouse; Hap43p-induced; flucytosine-, macrophage-, farnesol- induced; fluconazole, caspofungin repressed || 1 0.63 0.72 0.16 0.18 -0.62 -0.67 -0.42 -0.54 -0.90 -0.43 -0.29 -0.10 -0.68 -0.42
7394 || orf19.258 || || || Protein of unknown function; Spider biofilm induced || 1 0.69 0.62 1.15 1.71 -0.02 0.51 -0.36 -0.49 -0.62 -0.96 -0.84 -0.42 -0.73 -0.46 -0.55 -0.67
7395 || orf19.2836 || || || Protein with similarity to carbonic anhydrases || 1 0.66 0.93 1.62 2.20 0.13 0.16 -0.62 -0.79 -0.21 -1.19 -0.97 -0.75 -0.26 -1.14 -0.54 -0.58
7396 || orf19.5132 || || || Protein of unknown function; transcript detected on high-resolution tiling arrays; Spider biofilm induced || 1 0.38 0.61 1.14 1.40 0.14 0.20 -0.51 -1.00 -0.28 -0.86 -0.54 -0.75 -0.21 -0.32 -0.35 -0.44
7397 || orf19.3910 || || || Has domain(s) with predicted RNA binding, ribonuclease T2 activity || 1 0.71 0.70 1.08 1.05 0.04 0.37 -0.38 -0.77 -0.06 -1.04 -1.06 -0.30 -0.01 -0.52 -0.45 -0.47
7398 || orf19.5925 || || || Ortholog of S. cerevisiae : AIM6, C. glabrata CBS138 : CAGL0C05533g, C. dubliniensis CD36 : Cd36_84610, C. parapsilosis CDC317 : CPAR2_404550 and Candida tenuis NRRL Y-1498 : CANTEDRAFT_115337 || 1 1.10 1.15 1.43 1.65 0.11 0.60 -0.57 -0.87 -0.22 -0.66 -1.38 -0.74 -0.36 -0.47 -0.41 -1.01
7399 || orf19.7200 || || || Ortholog of C. dubliniensis CD36 : Cd36_73480, Pichia stipitis Pignal : PICST_30727, Candida tropicalis MYA-3404 : CTRG_05165 and Candida albicans WO-1 : CAWG_05712 || 1 1.40 1.31 1.76 1.70 -0.05 0.33 -0.49 -0.40 -0.34 -1.02 -1.44 -0.69 -0.00 -0.13 -0.36 -1.38
7400 || orf19.916 || || || Putative protein involved in apoptosis; Spider biofilm induced || 1 0.57 0.53 1.03 1.11 0.27 0.54 -0.38 -0.38 -0.18 -0.30 -0.99 -0.36 -0.37 -0.29 0.43 -0.35
7401 || orf19.5611 || || || Predicted 3-methylbutanol:NAD(P) oxidoreductase and methylglyoxal reductase (NADPH-dependent); role in ergosterol metabolic process; early stage flow model biofilm induced; Spider biofilm induced || 1 0.90 1.05 1.40 1.65 -0.19 1.10 -0.33 -1.60 -0.54 -0.29 -0.75 -0.91 -0.44 -0.35 -0.23 -0.54
7402 || orf19.751 || || || Ortholog of C. dubliniensis CD36 : Cd36_04660, Candida tropicalis MYA-3404 : CTRG_04484 and Candida albicans WO-1 : CAWG_00904 || 1 0.87 0.78 1.55 1.26 0.09 0.85 -0.64 -0.42 -0.77 -0.30 -0.92 -0.66 -0.61 -0.01 -0.36 -0.15
7403 || orf19.5461 || || || Ortholog of Candida albicans WO-1 : CAWG_02350 || 1 0.68 0.58 1.61 1.07 0.41 -0.04 -0.65 -0.37 0.17 -0.19 -0.64 0.01 -0.31 -0.33 -0.84 -0.26
7404 || orf19.3432 || || || Predicted membrane transporter, member of the drug:proton antiporter (12 spanner) (DHA1) family, major facilitator superfamily (MFS); induced by nitric oxide || 1 1.04 0.75 1.80 1.48 -0.28 0.12 -0.23 -0.54 0.76 -0.78 -0.87 -0.63 -0.83 -0.55 -0.86 -0.27
7405 || orf19.7320 || LIP7 || || Probable lipase, part of a gene family whose members are differentially expressed during infection; lacks a signal sequence for secretion, unlike other family members; may have a role in nutrition or in creating an acidic microenvironment || 1 0.61 0.49 0.92 1.00 0.11 0.42 -0.22 -0.22 0.63 -0.39 -0.60 -0.54 0.00 -0.00 -0.41 -0.03
7406 || orf19.1723 || || || Ortholog(s) have role in response to purine-containing compound and cytoplasm, nucleus localization || 1 0.79 0.64 0.97 1.06 -0.13 0.30 -0.20 -0.03 0.14 -0.11 -0.94 -0.50 -0.03 -0.20 -0.95 0.10
7407 || orf19.4864 || || || Ortholog(s) have acylglycerol lipase activity, serine hydrolase activity, role in triglyceride metabolic process and lipid particle, mitochondrial outer membrane, plasma membrane localization || 1 0.45 0.49 1.07 1.14 0.13 0.10 -0.24 -0.21 0.01 -0.23 -1.09 -0.45 -0.17 -0.08 -0.62 -0.41
7408 || orf19.3600 || || || Protein of unknown function; flow model biofilm induced || 1 0.43 0.38 1.08 1.18 -0.02 0.55 -0.41 -0.16 0.45 -0.02 -0.71 -0.28 -0.14 -0.05 -0.82 -0.17
7409 || orf19.4864 || || || Ortholog(s) have acylglycerol lipase activity, serine hydrolase activity, role in triglyceride metabolic process and lipid particle, mitochondrial outer membrane, plasma membrane localization || 1 0.53 0.47 1.00 1.09 0.24 0.40 -0.30 -0.33 -0.01 -0.32 -0.59 -0.45 0.00 0.08 -0.69 0.04
7410 || orf19.3601 || || || Has domain(s) with predicted ATP binding, nucleoside-triphosphatase activity || 1 0.65 0.47 1.35 1.27 0.05 0.53 -0.94 -0.62 -0.01 -0.53 -0.75 -0.71 0.04 -0.16 -1.16 -0.58
7411 || orf19.3374 || ECE1 || || Hypha-specific protein; regulated by Rfg1, Nrg1, Tup1, Cph1, Efg1, Hog1, farnesol, phagocytosis; fluconazole-induced; rat catheter and Spider biofilm induced; flow model biofilm repressed; Bcr1-repressed in RPMI a/a biofilms || 1 0.35 0.79 1.29 1.38 -0.40 0.04 -0.33 -0.21 0.24 -0.36 -0.07 -0.31 -0.14 -0.09 -0.57 -0.40
7412 || orf19.5293 || || || Ortholog of C. dubliniensis CD36 : Cd36_43710, C. parapsilosis CDC317 : CPAR2_402940, Candida tenuis NRRL Y-1498 : CANTEDRAFT_114940 and Debaryomyces hansenii CBS767 : DEHA2C09196g || 1 0.77 0.88 1.05 1.11 -0.15 -0.21 0.31 0.21 -0.16 -0.59 0.04 -0.46 -0.06 -0.51 -0.06 -0.14
7413 || orf19.5713 || YMX6 || || Putative NADH dehydrogenase; macrophage-downregulated gene; induced by nitric oxide; rat catheter biofilm induced || 1 0.41 0.43 0.62 1.03 -0.18 -0.06 -0.00 -0.06 -0.28 -0.46 -0.48 -0.59 -0.23 -0.13 0.29 -0.38
7414 || orf19.3418 || || || Ortholog(s) have endoplasmic reticulum, fungal-type vacuole localization || 1 0.30 0.50 1.12 1.43 0.14 -0.02 0.05 0.22 -0.27 -0.01 -0.51 -0.84 0.02 0.14 0.26 -0.70
7415 || orf19.2734 || || || Protein with a glucose/ribitol dehydrogenase family domain; mutants are viable || 1 0.98 1.16 2.02 2.77 0.18 -0.83 0.26 0.25 0.16 0.68 -0.63 -1.50 0.34 -0.31 -0.41 -1.30
7416 || orf19.2787 || PRY1 || || Pry family pathogenesis-related protein; extracellular; opaque specific transcript; repressed by alpha pheromone in SpiderM medium; possibly essential, disruptants not obtained by UAU1 method; Spider biofilm induced || 1 1.12 1.22 1.92 2.65 -0.00 -0.72 0.18 0.33 -0.42 0.06 -0.39 -0.88 0.02 -1.15 0.20 -0.71
7417 || orf19.7481 || MDH1 || || Mitochondrial malate dehydrogenase; regulated by Mig1, Tup1, white-opaque switch, phagocytosis; induced in high iron; antigenic during murine and human infection; repressed in Spider biofilms by Bcr1, Tec1, Ndt80, Rob1, Brg1 || 1 0.98 1.13 1.80 2.01 -0.13 -0.46 -0.30 0.21 -0.17 -0.12 -0.84 -0.84 -0.49 -0.57 0.09 -1.16
7418 || orf19.5426 || || || Putative patatin-like phospholipase; macrophage-regulated gene; fungal-specific (no human or murine homolog) || 1 0.96 1.04 1.37 1.85 0.11 -0.39 0.25 0.45 0.30 0.49 -0.67 -0.46 0.58 -0.39 -0.13 -0.30
7419 || orf19.6480 || || || Ortholog(s) have role in UDP-glucose transport and COPI-coated vesicle, Golgi apparatus localization || 1 0.48 0.63 1.01 1.02 0.09 -0.39 0.22 0.22 0.26 -0.09 -0.41 -0.17 0.35 0.01 -0.01 -0.10
7420 || orf19.707 || APG7 || || Ortholog(s) have APG12 activating enzyme activity, APG8 activating enzyme activity || 1 0.51 0.36 0.83 0.88 0.19 -0.00 -0.02 -0.14 0.14 -0.07 -0.49 0.03 0.12 -0.10 0.22 -0.17
7421 || orf19.3029 || || || Predicted 3-hydroxyisobutyryl-CoA hydrolase; mitochondrially localized; Spider biofilm induced || 1 0.85 0.81 0.97 1.19 0.37 0.26 -0.06 -0.04 0.25 0.03 -0.75 -0.11 0.10 0.02 0.13 -0.34
7422 || orf19.3029 || || || Predicted 3-hydroxyisobutyryl-CoA hydrolase; mitochondrially localized; Spider biofilm induced || 1 1.13 1.06 1.25 1.57 0.19 0.26 -0.14 0.27 0.32 -0.13 -1.04 -0.14 0.34 0.02 -0.10 -0.29
7423 || orf19.1089 || PEX11 || || Putative peroxisomal membrane protein; role in fatty acid oxidation; expression is Tac1-regulated; Hms1p-dependent induction by geldamycin; Spider biofilm induced || 1 0.89 0.84 1.10 1.35 0.05 0.09 -0.28 0.17 -0.23 -0.04 -0.46 0.08 0.05 0.27 0.10 -0.65
7424 || orf19.783 || || || Ortholog(s) have role in endocytosis, retrograde vesicle-mediated transport, Golgi to ER, vacuole organization and COPI-coated vesicle, Golgi membrane, endosome localization || 1 0.82 1.32 1.38 1.67 0.20 -0.08 -0.30 -0.05 -0.16 -0.00 -0.56 -0.13 -0.23 -0.32 -0.06 -0.04
7425 || orf19.656 || DPP1 || || Putative diacylglycerol pyrophosphate phosphatase of diacylglycerol production for phospholipid biosynthesis; downregulation correlates with clinical development of fluconazole resistance || 1 0.34 0.63 1.16 1.10 0.14 -0.12 0.14 -0.10 0.26 -0.31 -0.62 -0.06 0.19 -0.32 -0.46 -0.23
7426 || orf19.7661 || HMI1 || || ATP-dependent 3' - 5' helicase involved in maintenance of mitochondrial DNA; ortholog of S. cerevisiae Hmi1; rat catheter biofilm repressed || 1 0.80 0.81 1.22 1.33 -0.19 -0.03 0.18 -0.15 0.17 -0.62 -0.58 -0.39 0.10 -0.44 -0.17 -0.18
7427 || orf19.720 || GST3 || || Glutathione S-transferase; expression regulated upon white-opaque switch; induced by human neutrophils; peroxide-induced; induced by alpha pheromone in SpiderM medium; Spider biofilm induced || 1 1.11 1.12 1.67 1.97 0.61 0.53 -0.17 -0.28 0.29 -0.47 -0.75 -0.57 0.44 -0.69 -0.07 -0.43
7428 || orf19.115 || || || Ortholog of Candida tropicalis MYA-3404 : CTRG_02973 and Candida albicans WO-1 : CAWG_05252 || 1 0.71 0.62 1.06 1.42 0.47 -0.03 -0.21 -0.22 0.01 -0.53 -0.42 -0.16 0.19 -0.67 -0.19 -0.00
7429 || orf19.3376 || || || Ortholog of Candida albicans WO-1 : CAWG_03459 || 1 0.86 0.45 1.76 2.24 -0.00 0.66 -0.22 -0.10 -0.11 -0.51 -0.56 -0.55 0.06 -0.82 -0.74 -0.41
7430 || orf19.720 || GST3 || || Glutathione S-transferase; expression regulated upon white-opaque switch; induced by human neutrophils; peroxide-induced; induced by alpha pheromone in SpiderM medium; Spider biofilm induced || 1 0.71 0.63 1.58 2.12 0.14 0.90 0.37 -0.01 -0.01 -0.83 -0.76 -0.80 -0.04 -0.86 -0.15 -0.28
7431 || orf19.720 || GST3 || || Glutathione S-transferase; expression regulated upon white-opaque switch; induced by human neutrophils; peroxide-induced; induced by alpha pheromone in SpiderM medium; Spider biofilm induced || 1 0.78 0.80 1.45 2.32 -0.21 0.49 -0.18 0.16 0.02 -0.75 -0.73 -0.47 -0.37 -1.34 0.07 -0.37
7432 || orf19.3076 || || || Ortholog(s) have role in vesicle-mediated transport and COPI-coated vesicle, integral to Golgi membrane localization || 1 0.52 0.24 1.16 1.08 -0.25 0.17 0.05 0.13 0.12 -0.53 -0.33 -0.58 -0.25 -0.88 -0.02 -0.82
7433 || orf19.720 || GST3 || || Glutathione S-transferase; expression regulated upon white-opaque switch; induced by human neutrophils; peroxide-induced; induced by alpha pheromone in SpiderM medium; Spider biofilm induced || 1 0.85 1.06 1.78 2.11 -0.29 0.39 -0.36 -0.58 0.08 -0.56 -1.14 -0.93 -0.25 -1.36 -0.45 -0.95
7434 || orf19.6826 || SLF1 || || Putative polysome-associated RNA binding protein; macrophage-induced gene || 1 1.47 1.53 2.13 2.56 -0.63 0.07 -0.30 -0.08 -0.15 -0.98 -0.93 -1.67 -0.65 -2.01 -0.26 -1.47
7435 || orf19.376 || || || Protein of unknown function; Hap43-repressed; Spider biofilm induced || 1 1.15 1.02 1.79 2.18 -0.64 -0.20 -0.17 -0.47 -0.35 -0.68 -1.20 -1.63 -0.67 -1.57 -0.66 -1.01
7436 || orf19.6830 || || || Putative enoyl-CoA hydratase; Spider biofilm induced || 1 1.53 1.19 2.14 2.29 -0.40 -0.15 0.27 -0.03 0.10 -0.14 -1.18 -1.19 -0.44 -0.97 -0.42 -1.31
7437 || orf19.720 || GST3 || || Glutathione S-transferase; expression regulated upon white-opaque switch; induced by human neutrophils; peroxide-induced; induced by alpha pheromone in SpiderM medium; Spider biofilm induced || 1 1.44 1.03 1.98 2.16 -0.39 0.47 0.40 -0.23 0.16 -0.44 -0.52 -0.86 -0.48 -0.71 -0.34 -0.86
7438 || orf19.5520 || ASG7 || || a-cell specific protein of unknown function; two predicted transmembrane domains; member of conserved Mcm1 regulon; induced by alpha pheromone in SpiderM medium || 1 1.70 1.43 1.75 2.23 -0.89 0.05 -0.10 -0.68 0.17 -0.29 -1.04 -0.96 -0.84 -1.05 -0.45 -0.47
7439 || orf19.7077 || || || Putative ferric reductase; induced by Mac1 under copper starvation; Plc1-regulated; Rim101-repressed || 1 0.75 0.72 1.65 1.63 -0.46 0.71 0.28 -0.52 -0.19 -0.72 -0.94 -0.69 0.01 -0.41 0.25 -0.14
7440 || orf19.2711.1 || MED20 || || Subunit of the RNA polymerase II mediator complex; involved in control of filamentous growth and Spider biofilm formation; rat catheter biofilm repressed || 1 0.42 0.38 0.80 0.70 -0.10 0.09 0.09 0.15 -0.09 -0.32 -0.47 -0.45 0.02 -0.30 0.20 -0.13
7441 || orf19.6844 || ICL1 || || Isocitrate lyase; glyoxylate cycle enzyme; required for virulence in mice; induced upon phagocytosis by macrophage; farnesol regulated; Pex5-dependent peroxisomal localization; stationary phase enriched; rat catheter, Spider biofilm induced || 1 0.70 0.75 1.93 1.94 -0.32 -0.29 -0.14 -0.64 0.30 -0.13 -1.11 -1.04 -0.31 -0.35 -0.04 -0.30
7442 || orf19.7472 || IFF4 || || Adhesin-like cell surface protein; putative GPI-anchor; null mutant germ tubes show decreased adhesion to plastic substrate; mutants are viable; Hap43-repressed gene || 1 0.36 0.64 1.28 1.33 -0.19 -0.00 -0.13 -0.41 -0.11 -0.69 -1.16 -0.85 0.25 -0.23 -0.04 -0.49
7443 || orf19.5270 || || || Protein of unknown function; rat catheter biofilm induced || 1 0.90 0.61 1.13 0.98 0.37 0.27 0.01 0.06 0.14 -0.14 -0.93 -0.85 0.09 -0.22 0.24 -0.27
7444 || orf19.3740 || PGA23 || || Putative GPI-anchored protein of unknown function; Rim101-repressed; Cyr1-regulated; colony morphology-related gene regulation by Ssn6 || 1 0.65 0.52 0.61 0.97 0.31 -0.29 -0.15 0.05 0.69 0.08 -0.66 0.16 -0.10 -0.49 -0.29 -1.21
7445 || orf19.5000 || CYB2 || || Putative cytochrome b2 precursor; induced in high iron; alkaline repressed; colony morphology-related gene regulation by Ssn6; Hap43-repressed; pider biofilm induced || 1 0.63 0.76 1.14 1.08 0.40 0.18 -0.58 -0.62 0.78 -0.03 -0.99 -0.23 0.19 -0.72 0.23 -1.20
7446 || orf19.5250 || || || Has domain(s) with predicted cofactor binding activity || 1 0.75 1.02 1.30 1.57 -0.09 0.37 -0.49 -0.49 0.43 0.22 -0.93 -0.38 -0.39 -0.59 -0.10 -0.89
7447 || orf19.5000 || CYB2 || || Putative cytochrome b2 precursor; induced in high iron; alkaline repressed; colony morphology-related gene regulation by Ssn6; Hap43-repressed; pider biofilm induced || 1 0.93 0.96 1.40 1.84 -0.16 0.24 -0.07 -0.09 0.60 0.02 -1.13 -0.23 -0.33 -1.28 0.07 -1.90
7448 || orf19.5000 || CYB2 || || Putative cytochrome b2 precursor; induced in high iron; alkaline repressed; colony morphology-related gene regulation by Ssn6; Hap43-repressed; pider biofilm induced || 1 0.95 0.83 1.36 1.29 -0.07 0.57 0.14 -0.21 0.69 0.01 -0.75 -0.19 -0.50 -0.91 0.30 -1.53
7449 || orf19.5215 || TES15 || || Putative acyl-CoA thioesterase; Hap43-repressed; Spider biofilm induced || 1 0.37 0.51 0.64 1.31 -0.17 0.13 0.21 -0.03 0.81 0.33 -1.15 -0.94 -0.15 -0.25 0.14 -1.31
7450 || orf19.6274 || PBR1 || || Protein of unknown function; required for cohesion, adhesion, and RPMI biofilm formation; induced by alpha pheromone in white cells; fluconazole-induced; Spider biofilm induced || 1 1.47 0.96 1.51 1.38 0.20 -0.18 0.23 -0.34 1.23 0.23 -1.45 -1.47 0.27 -1.23 0.18 -1.40
7451 || orf19.2599 || CRC1 || || Mitochondrial carnitine carrier protein || 1 0.77 0.43 0.46 0.90 0.12 -0.32 -0.18 0.02 0.55 0.35 -0.54 -0.29 -0.05 -0.19 0.10 -0.59
7452 || orf19.3874 || || || Predicted cation transmembrane transporter; Spider biofilm induced || 1 1.22 0.84 1.11 1.33 -0.37 0.10 0.09 -0.03 0.63 0.51 -1.01 -0.60 0.19 0.01 -0.20 -1.19
7453 || orf19.6782 || BMT1 || || Beta-mannosyltransferase, required for addition of the 1st beta-mannose residue to acid-stable fraction of cell wall phosphopeptidomannan; 9-gene family member; mutants induce higher levels of inflammatory cytokines in mouse dendritic cells || 1 1.23 1.03 1.23 1.41 -0.18 0.16 -0.05 -0.19 0.29 0.83 -1.39 -0.87 0.23 -0.29 -0.19 -1.32
7454 || orf19.2809 || CTN3 || || Peroxisomal carnitine acetyl transferase; no obvious metabolic, hyphal, virulence defects in Ura+ strain; induced by macrophage engulfment, hyphal growth, starvation, nonfermentable carbon sources; rat catheter, Spider biofilm induced || 1 0.88 0.43 0.69 0.75 -0.10 -0.30 -0.02 -0.18 0.42 0.29 -1.46 -0.46 0.11 0.08 0.03 -1.04
7455 || orf19.5000 || CYB2 || || Putative cytochrome b2 precursor; induced in high iron; alkaline repressed; colony morphology-related gene regulation by Ssn6; Hap43-repressed; pider biofilm induced || 1 1.08 1.05 1.04 1.29 -0.60 0.53 0.01 -0.29 1.09 0.44 -2.19 -0.24 -0.69 -1.08 0.36 -1.75
7456 || orf19.5000 || CYB2 || || Putative cytochrome b2 precursor; induced in high iron; alkaline repressed; colony morphology-related gene regulation by Ssn6; Hap43-repressed; pider biofilm induced || 1 0.80 0.81 1.21 0.98 -0.63 0.33 -0.26 -0.47 0.92 0.04 -2.40 -0.50 -1.32 -1.48 0.11 -2.73
7457 || orf19.2202 || || || Protein of unknown function; induced by alpha pheromone in SpiderM medium || 1 0.56 0.62 0.73 1.05 -0.11 -0.14 -0.12 -0.05 0.61 0.91 -0.82 -0.59 -0.66 -0.88 0.05 -2.46
7458 || orf19.2202 || || || Protein of unknown function; induced by alpha pheromone in SpiderM medium || 1 0.86 0.89 0.94 1.09 0.03 -0.17 -0.06 -0.08 0.57 0.51 -1.31 -1.38 -0.27 -1.05 -0.04 -2.79
7459 || orf19.5655 || || || Has domain(s) with predicted 2 iron, 2 sulfur cluster binding, iron ion binding, oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen and NAD(P)H as one donor, more || 1 0.31 0.17 0.89 0.64 0.07 0.01 -0.53 -0.40 0.42 0.26 -1.03 -1.24 -0.32 -0.98 -0.61 -1.64
7460 || orf19.2202 || || || Protein of unknown function; induced by alpha pheromone in SpiderM medium || 1 -0.10 0.15 1.04 1.14 0.28 -0.16 -0.39 -0.52 0.56 0.75 -1.23 -1.16 -0.33 -0.87 -0.63 -1.93
7461 || orf19.935 || AGA1 || || Protein with some similarity to agglutinin subunit; expression regulated upon white-opaque switch; Spider biofilm induced || 1 1.39 0.92 1.18 1.97 -0.65 -0.53 -0.59 -0.89 0.63 0.65 -0.87 -1.82 0.20 -0.86 -0.55 -1.75
7462 || orf19.2809 || CTN3 || || Peroxisomal carnitine acetyl transferase; no obvious metabolic, hyphal, virulence defects in Ura+ strain; induced by macrophage engulfment, hyphal growth, starvation, nonfermentable carbon sources; rat catheter, Spider biofilm induced || 1 0.52 0.37 0.66 0.87 -0.48 -0.03 -0.57 -0.65 0.74 0.27 -1.47 -0.95 -0.53 -0.20 -0.30 -0.86
7463 || orf19.3234 || OYE22 || || Putative NADPH dehydrogenase; rat catheter biofilm induced || 1 0.78 0.60 0.73 1.20 -0.90 0.06 0.31 -0.06 0.55 0.31 -1.56 -1.15 -0.43 -0.46 -0.09 -1.11
7464 || orf19.3234 || OYE22 || || Putative NADPH dehydrogenase; rat catheter biofilm induced || 1 0.51 0.46 0.39 0.61 -0.97 0.01 0.23 -0.18 0.36 0.33 -1.54 -1.22 -0.50 0.01 -0.26 -0.89
7465 || orf19.5337 || UBC15 || || Putative E2 ubiquitin-conjugating enzyme || 1 0.76 0.67 0.54 0.66 0.23 -0.27 -0.11 -0.15 -0.13 -0.10 -0.35 -0.89 -0.13 -0.33 -0.09 -0.36
7466 || orf19.6306 || || || Trimethylaminobutyraldehyde dehydrogenase, the third enzyme of the carnitine biosynthesis pathway || 1 0.62 0.53 0.83 1.13 0.07 -0.67 -0.19 -0.10 0.37 -0.20 -0.61 -0.38 0.36 -0.23 -0.24 -0.35
7467 || orf19.4922 || || || Ortholog(s) have Rab GTPase binding activity and Golgi apparatus, endoplasmic reticulum localization || 1 0.25 0.26 0.87 0.57 0.23 -0.50 0.14 0.28 -0.07 -0.16 -0.33 -0.35 -0.08 0.02 -0.01 -0.08
7468 || orf19.1723 || || || Ortholog(s) have role in response to purine-containing compound and cytoplasm, nucleus localization || 1 0.82 0.62 1.16 1.03 0.53 -0.06 0.40 0.49 -0.05 -0.34 -0.57 -0.51 0.19 0.17 -0.22 0.04
7469 || orf19.4570 || || || Ortholog of C. dubliniensis CD36 : Cd36_42090, Debaryomyces hansenii CBS767 : DEHA2C14872g, Pichia stipitis Pignal : PICST_74821 and Spathaspora passalidarum NRRL Y-27907 : SPAPADRAFT_58607 || 1 0.45 0.63 0.89 1.27 0.75 -0.16 0.00 0.32 0.22 -0.20 -0.66 -0.94 0.13 0.51 -0.03 -0.49
7470 || orf19.3444 || || || Predicted membrane transporter, member of the drug:proton antiporter (14 spanner) (DHA2) family, major facilitator superfamily (MFS); Hap43p-repressed gene || 1 0.54 0.89 1.62 1.98 1.03 0.12 0.34 0.34 0.57 0.25 -1.00 -1.15 -0.20 0.12 -0.61 -0.79
7471 || orf19.7371 || ZCF35 || || Zn(II)2Cys6 transcription factor; Hap43-induced; Spider biofilm induced || 1 0.51 0.66 0.98 0.53 0.58 0.51 -0.06 -0.25 0.22 -0.19 -0.30 -0.63 0.23 -0.09 -0.10 -0.24
7472 || orf19.3142 || || || Ortholog of C. dubliniensis CD36 : Cd36_46140, C. parapsilosis CDC317 : CPAR2_501210, Candida tenuis NRRL Y-1498 : CANTEDRAFT_97195 and Debaryomyces hansenii CBS767 : DEHA2E08800g || 1 0.78 1.05 0.93 1.37 0.35 0.04 0.13 -0.29 1.09 -0.59 -0.69 -0.33 0.44 -0.04 -0.67 -0.52
7473 || orf19.5741 || ALS1 || || Cell-surface adhesin; adhesion, virulence, immunoprotective roles; band at hyphal base; Rfg1, Ssk1, Spider biofilm induced; flow model biofilm repressed; CAI-4 strain background effects; promoter bound Bcr1, Tec1, Efg1, Ndt80, and Brg1 || 1 0.70 1.14 1.24 1.32 0.44 0.41 0.47 0.09 1.58 0.30 -0.82 -0.94 1.53 -0.09 -0.29 -0.98
7474 || orf19.4568 || ZCF25 || || Putative Zn(II)2Cys6 transcription factor || 1 0.62 1.16 1.59 1.12 0.50 0.78 -0.00 -0.12 1.31 0.50 -1.25 -1.04 0.80 -0.10 -0.89 -0.52
7475 || orf19.3151 || || || Has domain(s) with predicted catalytic activity, coenzyme binding activity and role in cellular metabolic process || 1 0.34 0.63 1.06 0.87 0.57 0.23 -0.20 -0.21 0.66 0.12 -0.54 -0.38 0.57 0.14 -0.27 -0.44
7476 || orf19.499 || || || Ortholog(s) have S-adenosylmethionine-dependent methyltransferase activity, role in translational readthrough and mitochondrion localization || 1 0.55 0.73 1.04 0.93 0.27 0.28 -0.20 -0.42 0.58 -0.03 -0.73 -0.44 0.38 0.18 -0.21 -0.66
7477 || orf19.4274 || PUT1 || || Putative proline oxidase; alkaline upregulated by Rim101; flow model biofilm induced; Spider biofilm induced || 1 0.94 0.94 1.77 1.72 0.25 0.31 -0.50 -0.51 1.04 0.20 -0.80 -0.64 0.56 0.27 0.00 -0.65
7478 || orf19.5717 || || || Ortholog of Candida albicans WO-1 : CAWG_05019 || 1 0.47 0.57 0.80 0.79 0.20 0.22 -0.31 -0.05 0.48 -0.26 -0.41 -0.24 0.33 0.07 -0.21 -0.25
7479 || orf19.3084 || || || Ortholog(s) have histone acetyltransferase activity, role in chromatin silencing at telomere and SAS acetyltransferase complex, nuclear chromatin localization || 1 0.38 0.67 0.69 0.75 0.31 0.14 -0.37 -0.15 0.27 -0.21 -0.24 -0.64 0.38 -0.07 -0.36 -0.41
7480 || orf19.5307 || JEN2 || || Dicarboxylic acid transporter; regulated by glucose repression; induced by Rgt1; disruptants not obtained by UAU1 method; rat catheter and Spider biofilm induced || 1 1.65 2.11 2.36 2.67 1.11 -0.13 -0.52 -0.79 0.57 0.29 -1.07 -2.06 0.87 -1.58 -0.83 -1.72
7481 || orf19.854 || UGA11 || || Putative gamma-aminobutyrate (GABA) transaminase; macrophage-induced; overlaps orf19.854.1, which is a region annotated as a blocked reading frame; Spider biofilm induced || 1 0.26 0.62 1.19 1.30 0.50 0.06 -0.37 -0.20 0.44 0.28 -0.65 -0.87 0.71 -0.43 -0.46 -0.62
7482 || orf19.6083 || || || Has domain(s) with predicted nucleic acid binding, nucleotide binding activity || 1 0.52 0.40 0.79 0.95 0.37 -0.20 -0.26 -0.02 0.33 0.01 -0.14 -0.22 0.38 -0.10 -0.09 -0.50
7483 || orf19.6480 || || || Ortholog(s) have role in UDP-glucose transport and COPI-coated vesicle, Golgi apparatus localization || 1 0.29 0.67 1.05 0.79 0.22 -0.05 0.22 0.11 0.43 0.13 0.08 -0.29 0.69 -0.14 -0.20 -0.61
7484 || orf19.4510 || IFA4 || || Protein of unknown function; oxidative stress-induced via Cap1 || 1 0.49 0.33 1.18 0.97 0.30 0.11 0.10 0.14 0.72 0.64 -0.38 -0.68 0.46 -0.54 -0.46 -0.10
7485 || orf19.5565 || || || Putative 3-hydroxyisobutyrate dehydrogenase; rat catheter and Spider biofilm induced || 1 0.05 0.29 1.23 1.09 0.22 0.09 0.01 -0.01 0.30 0.56 -0.60 -0.52 0.61 -0.42 -0.16 -0.48
7486 || orf19.7071 || FGR2 || || Protein similar to phosphate transporters; transposon mutation affects filamentous growth; expression is regulated upon white-opaque switching || 1 0.67 0.52 1.44 2.09 0.52 0.68 -0.01 0.13 -0.07 0.42 -0.60 -1.35 0.64 -0.85 -0.07 -0.71
7487 || orf19.2504 || BMS1 || || Putative GTPase; Hap43-induced gene; mutation confers resistance to 5-fluorocytosine (5-FC); flucytosine induced; repressed by prostaglandins; Spider biofilm induced || 1 0.28 0.32 1.47 1.41 0.25 0.46 0.30 0.33 -0.10 0.27 -0.26 -0.88 0.34 -0.38 -0.00 -0.59
7488 || orf19.6083 || || || Has domain(s) with predicted nucleic acid binding, nucleotide binding activity || 1 0.61 0.40 1.30 1.07 -0.18 0.28 0.11 0.29 0.17 0.39 -0.45 -0.59 0.19 -0.14 -0.33 -0.47
7489 || orf19.5565 || || || Putative 3-hydroxyisobutyrate dehydrogenase; rat catheter and Spider biofilm induced || 1 0.55 0.40 1.43 1.60 0.14 0.00 0.09 0.28 0.38 0.97 -0.43 -0.66 0.27 -0.41 0.56 -0.25
7490 || orf19.3434 || TRY5 || || Zn(II)2Cys6 transcription factor; regulator of yeast form adherence; required for yeast cell adherence to silicone substrate || 1 0.95 1.05 1.66 1.76 0.61 -0.43 -0.02 -0.25 0.64 1.02 -1.59 -2.01 1.75 0.05 -0.56 -1.15
7491 || orf19.3434 || TRY5 || || Zn(II)2Cys6 transcription factor; regulator of yeast form adherence; required for yeast cell adherence to silicone substrate || 1 0.65 0.71 1.20 1.86 0.02 -0.46 -0.28 -0.44 0.48 0.39 -1.68 -1.85 1.43 -0.04 -0.38 -0.60
7492 || orf19.3435 || || || Ortholog of Candida albicans WO-1 : CAWG_05215 || 1 0.71 0.64 1.78 2.05 0.50 -0.07 -0.29 -0.54 0.63 0.84 -2.29 -1.79 1.21 0.08 -0.66 -0.59
7493 || orf19.3435 || || || Ortholog of Candida albicans WO-1 : CAWG_05215 || 1 0.45 0.50 1.28 2.01 0.16 -0.10 -0.13 -0.46 0.62 1.02 -2.73 -1.69 1.05 0.39 -0.85 -1.10
7494 || orf19.4568 || ZCF25 || || Putative Zn(II)2Cys6 transcription factor || 1 0.50 0.63 0.56 0.88 0.33 -0.06 0.00 0.19 0.31 0.54 -0.67 -0.24 0.30 0.13 -0.44 -0.42
7495 || orf19.7175 || HLJ1 || || Putative HSP40 co-chaperone; repressed during the mating process || 1 0.63 0.56 0.55 0.52 0.59 0.07 -0.12 0.04 0.26 0.32 -0.37 -0.73 0.53 0.25 -0.10 -0.49
7496 || orf19.1587 || HGT20 || || Putative glucose transporter of the major facilitator superfamily; the C. albicans glucose transporter family comprises 20 members; 12 probable membrane-spanning segments; regulated by Nrg1 || 1 0.37 0.42 0.71 0.85 -0.28 -1.04 0.27 0.34 0.55 -0.06 -0.95 -1.08 0.10 0.60 -0.70 -0.23
7497 || orf19.5848 || || || RING-type zinc finger protein; upregulated during oral infection; mutants have reduced ability to damage oral epithelial cells; Spider and flow model biofilm induced || 1 0.76 0.88 0.81 0.58 -0.69 -1.14 0.46 -0.29 0.40 -0.26 -1.16 -1.13 0.29 -0.13 -0.62 -0.98
7498 || orf19.5848 || || || RING-type zinc finger protein; upregulated during oral infection; mutants have reduced ability to damage oral epithelial cells; Spider and flow model biofilm induced || 1 0.86 1.00 0.89 0.75 -0.22 -0.80 0.40 -0.12 0.56 -0.14 -0.98 -1.20 0.51 -0.03 -0.44 -0.64
7499 || orf19.2810 || AAP1 || || Putative amino acid permease; fungal-specific; possibly essential, disruptants not obtained by UAU1 method; Spider biofilm induced || 1 1.40 1.27 2.21 2.37 -0.88 -1.71 -0.07 -0.09 0.25 0.35 -1.07 0.41 -0.54 -1.62 -1.41
7500 || orf19.6938 || MEU1 || || Putative methylthioadenosine phosphorylase; protein level decreases in stationary phase cultures || 1 1.17 1.19 1.23 1.66 -0.94 -0.73 -0.12 0.27 0.16 0.65 -1.10 -1.14 -0.64 -0.29 -1.36 -0.76
7501 || orf19.6938 || MEU1 || || Putative methylthioadenosine phosphorylase; protein level decreases in stationary phase cultures || 1 1.04 1.04 1.34 1.65 -1.10 -0.78 0.00 0.11 -0.05 0.41 -0.95 -1.36 -0.38 -0.50 -1.64 -1.27
7502 || orf19.4197 || YHM2 || || Predicted carrier protein; exports citrate from and imports oxoglutarate into the mitochondrion; alkaline induced; Spider biofilm repressed || 1 0.54 0.70 0.88 0.99 -0.58 -0.55 -0.10 0.05 -0.44 0.54 -0.42 -1.05 0.03 0.02 -0.63 -0.76
7503 || orf19.4197 || YHM2 || || Predicted carrier protein; exports citrate from and imports oxoglutarate into the mitochondrion; alkaline induced; Spider biofilm repressed || 1 1.17 1.19 1.46 1.73 -1.61 -1.15 -0.11 0.67 -0.39 0.85 -1.38 -1.47 0.34 0.54 -2.00 -1.63
7504 || orf19.4381 || VTC3 || || Putative polyphosphate synthetase; downregulated in core caspofungin response; Hog1p-induced; transcription is opaque-specific; fungal-specific (no human or murine homolog) || 1 1.43 1.47 1.45 2.02 -0.81 -0.49 -0.03 0.29 0.14 0.34 -2.02 -1.29 0.68 -0.08 -2.07 -2.52
7505 || orf19.5615 || AYR2 || || Putative NADPH-dependent 1-acyl dihydroxyacetone phosphate reductase; shows colony morphology-related gene regulation by Ssn6p || 1 0.77 0.73 0.82 1.09 -0.17 -0.10 -0.34 0.17 -0.12 0.18 -1.01 -0.97 -0.03 -0.07 -1.08 -0.73
7506 || orf19.1860 || LSC2 || || Putative succinate-CoA ligase beta subunit; regulated by Mig1, Tup1; induced in high iron; protein present in exponential and stationary growth phase yeast cells; Spider biofilm repressed || 1 1.03 1.03 -0.20 -0.02 0.06 0.33 0.20 0.14 -1.35 -1.48 0.01 0.35 -1.90 -1.16
7507 || orf19.3097 || PDA1 || || Putative pyruvate dehydrogenase alpha chain; fluconazole-induced; protein present in exponential and stationary growth phase yeast cultures; Hap43-induced; Spider biofilm repressed || 1 0.83 0.75 0.66 0.71 -0.32 -0.14 -0.08 0.20 0.18 -0.01 -0.58 -0.56 -0.12 0.29 -0.72 -0.54
7508 || orf19.4972 || || || Putative transcription factor with zinc finger DNA-binding motif || 1 1.09 0.47 1.32 1.22 -0.78 -0.41 0.33 0.29 1.05 0.46 -0.86 -1.09 0.45 0.21 -0.83 -1.09
7509 || orf19.5534 || || || Protein with a predicted role in mitotic spindle elongation, vesicle-mediated transport; flow model biofilm induced || 1 0.43 1.02 1.57 1.22 -0.54 -0.92 0.22 0.21 0.33 0.37 -1.11 -1.11 0.01 0.43 -0.46 -0.96
7510 || orf19.6534 || || || Ortholog of Candida albicans WO-1 : CAWG_05537 || 1 0.37 0.45 0.81 0.88 -0.07 -0.22 0.31 0.20 0.35 0.09 -0.54 -0.81 0.38 -0.05 -0.11 -0.70
7511 || orf19.1325 || ECM38 || || Putative gamma-glutamyltransferase; alkaline upregulated; Spider biofilm induced; possibly an essential gene, disruptants not obtained by UAU1 method || 1 0.56 0.47 0.89 1.62 -0.58 -0.40 0.31 0.09 0.62 0.06 -1.37 -0.97 0.12 0.24 -0.05 -0.73
7512 || orf19.1037 || || || Protein of unknown function; rat catheter biofilm repressed || 1 0.35 0.58 0.95 0.70 -0.14 -0.47 0.14 -0.10 0.24 -0.24 -0.87 -0.75 0.17 0.60 -0.60 -0.14
7513 || orf19.5614 || || || Putative ribonuclease H1; possibly an essential gene, disruptants not obtained by UAU1 method; flow model biofilm induced; Spider biofilm induced || 1 1.05 1.05 1.22 1.08 -0.60 -0.63 -0.35 -0.75 0.02 -0.20 -2.02 -1.64 0.91 0.85 -0.92 -0.68
7514 || orf19.5614 || || || Putative ribonuclease H1; possibly an essential gene, disruptants not obtained by UAU1 method; flow model biofilm induced; Spider biofilm induced || 1 1.19 1.22 1.66 1.48 -0.26 -0.31 -0.33 -0.60 0.36 0.02 -1.81 -1.40 1.44 0.79 -0.82 -1.17
7515 || orf19.1611 || || || Protein of unknown function; Spider biofilm induced || 1 1.47 1.49 1.86 1.83 -0.50 -0.14 0.22 -0.08 0.54 0.44 -1.81 -2.05 1.11 1.19 -1.54 -1.56
7516 || orf19.5548 || LYS14 || || Zn(II)2Cys6 transcription factor; has similarity to S. cerevisiae Lys14, which is a transcription factor involved in the regulation of lysine biosynthesis genes || 1 0.41 0.33 1.07 0.78 -0.35 0.14 0.14 -0.33 0.24 -0.04 -0.83 -0.61 0.26 0.49 -0.84 -0.57
7517 || orf19.1596 || FGR28 || || Protein lacking an ortholog in S. cerevisiae; transposon mutation affects filamentous growth; possibly an essential gene, disruptants not obtained by UAU1 method || 1 0.54 0.50 1.01 1.01 0.25 0.13 -0.24 -0.11 0.61 0.10 -1.01 -0.65 -0.09 0.27 -0.67 -0.55
7518 || orf19.3601 || || || Has domain(s) with predicted ATP binding, nucleoside-triphosphatase activity || 1 0.49 0.22 0.94 1.06 -0.24 0.11 -0.21 -0.35 0.56 -0.02 -0.79 -0.87 0.02 0.15 -0.72 -0.77
7519 || orf19.3444 || || || Predicted membrane transporter, member of the drug:proton antiporter (14 spanner) (DHA2) family, major facilitator superfamily (MFS); Hap43p-repressed gene || 1 0.86 0.82 1.71 1.58 -0.93 -0.44 0.27 0.18 1.04 0.13 -2.11 -1.99 -0.17 0.19 -1.67 -1.45
7520 || orf19.1596 || FGR28 || || Protein lacking an ortholog in S. cerevisiae; transposon mutation affects filamentous growth; possibly an essential gene, disruptants not obtained by UAU1 method || 1 0.14 0.17 0.44 0.61 -0.20 -0.11 -0.01 -0.16 0.53 -0.02 -1.38 -0.81 -0.09 0.09 -0.77 -0.51
7521 || orf19.4826 || IDH1 || || Putative mitochondrial NAD-isocitrate dehydrogenase subunit 1; soluble protein in hyphae; protein level decrease in stationary phase cultures || 1 0.40 0.21 0.54 0.63 -0.21 -0.21 -0.18 -0.15 -0.05 0.02 -1.18 -0.95 0.08 0.50 -0.94 -0.39
7522 || orf19.1714 || PGA44 || || Putative GPI-anchored protein || 1 1.18 1.44 1.45 1.24 -1.87 -1.08 -1.16 -0.99 0.64 0.53 -2.60 -1.15 0.24 0.89 -1.84
7523 || orf19.4916 || || || Protein of unknown function; induced by alpha pheromone in SpiderM medium || 1 0.44 0.33 1.14 0.57 0.04 -0.07 0.11 0.04 0.33 -0.48 -0.78 -0.52 0.23 0.13 -0.23 -0.39
7524 || orf19.5717 || || || Ortholog of Candida albicans WO-1 : CAWG_05019 || 1 -0.00 0.38 0.34 0.61 0.01 0.04 -0.23 -0.04 0.14 -0.24 -0.27 -0.52 -0.34 -0.02 -0.20 -0.13
7525 || orf19.6520 || || || Putative allantoate permease; fungal-specific (no human or murine homolog) || 1 0.63 0.55 0.37 2.33 -0.37 -0.44 -1.09 -1.09 -0.16 -0.44 -1.53 -1.84 -1.41 -0.61 -0.20 -1.19
7526 || orf19.2429 || || || Protein of unknown function; induced by alpha pheromone in SpiderM medium || 1 0.39 0.22 0.83 1.65 0.26 0.06 -0.34 -0.38 0.23 -0.05 -0.48 -0.60 -0.44 -0.28 -0.59 -0.73
7527 || orf19.700 || SEO1 || || Protein with similarity to permeases; Sfu1-repressed; flucytosine induced; induced by Mnl1 under weak acid stress; flow model biofilm repressed || 1 0.23 0.02 0.65 1.49 -0.58 -0.11 -0.29 -0.14 0.44 -0.08 -0.63 -0.35 -0.60 -0.23 -0.56 -0.47
7528 || orf19.1855 || || || Predicted membrane transporter, member of the anion:cation symporter (ACS) family, major facilitator superfamily (MFS); Gcn4p-regulated; flucytosine induced; ketoconazole-repressed; oxidative stress-induced via Cap1p || 1 0.34 0.16 0.57 1.51 -0.09 -0.22 -0.28 -0.09 0.30 -0.08 -0.61 -0.33 -1.15 -0.29 -0.38 -0.18
7529 || orf19.1089 || PEX11 || || Putative peroxisomal membrane protein; role in fatty acid oxidation; expression is Tac1-regulated; Hms1p-dependent induction by geldamycin; Spider biofilm induced || 1 0.51 0.47 0.75 0.87 -0.39 -0.33 -0.36 0.12 -0.29 -0.08 -0.67 0.05 -0.43 -0.20 -0.28 -0.90
7530 || orf19.1804 || || || Ortholog(s) have role in cellular response to cadmium ion, detoxification of cadmium ion and mitochondrion localization || 1 0.67 0.29 0.79 0.55 -0.24 -0.03 -0.11 -0.09 0.24 -0.29 -0.40 0.20 -0.02 -0.29 -0.13 -0.90
7531 || orf19.3458 || || || Ortholog(s) have role in late endosome to vacuole transport via multivesicular body sorting pathway, protein targeting to vacuole and Golgi apparatus, Vps55/Vps68 complex, fungal-type vacuole membrane, mitochondrion localization || 1 0.35 0.36 0.71 0.94 -0.21 -0.14 -0.24 -0.07 0.10 0.01 -0.29 0.22 0.12 -0.20 -0.14 -0.32
7532 || orf19.4306 || || || Ortholog(s) have methylthioribulose 1-phosphate dehydratase activity, role in L-methionine salvage from methylthioadenosine and cytoplasm localization || 1 1.23 1.21 1.46 1.59 -0.61 0.16 -0.52 -0.03 0.18 0.52 -0.36 0.14 0.01 0.24 -0.73 -0.64
7533 || orf19.7354 || LAC1 || || Ceramide synthase; required for biosynthesis of ceramides with C18:0 fatty acids, which serve as precursors for glucosylsphingolipids; caspofungin induced || 1 0.68 0.48 0.78 0.93 -0.07 0.22 -0.04 -0.11 0.12 0.49 -0.32 -0.12 0.08 -0.35 -0.75 -0.94
7534 || orf19.6574 || ALK6 || || Putative cytochrome P-450 of N-alkane-induced detoxification; macrophage-induced gene || 1 0.87 -0.05 0.96 1.32 -0.34 0.23 0.15 -0.46 1.50 -0.33 -1.01 0.48 0.22 -0.34 -0.45
7535 || orf19.1778 || || || Dubious open reading frame || 1 1.48 0.78 1.65 2.01 -0.68 1.03 -0.97 -0.95 1.70 -0.22 -1.40 -0.21 -0.68 -0.76 -0.16
7536 || orf19.271 || ADH4 || || Predicted 3-hydroxyacyl-CoA dehydrogenase; transcript is increased in azole-resistant strain overexpressing MDR1; transcript is increased in populations of cells exposed to fluconazole over multiple generations; mutant is viable || 1 1.17 0.31 1.01 1.58 -0.54 0.81 -0.24 0.20 1.14 0.33 -0.87 -0.69 -0.18 -0.35 -0.62 -0.63
7537 || orf19.3942 || || || Ortholog(s) have structural molecule activity || 1 0.86 -0.09 0.82 1.61 -0.25 0.34 -0.30 -0.15 0.82 -0.30 -0.60 0.15 -0.03 -0.43 -0.15 -0.96
7538 || orf19.4341 || || || Ortholog(s) have role in attachment of GPI anchor to protein, conidium formation, hyphal growth, sporocarp development involved in sexual reproduction and GPI-anchor transamidase complex localization || 1 0.79 0.01 0.35 1.05 -0.30 0.16 -0.39 -0.07 0.61 -0.24 -0.70 -0.17 -0.08 -0.07 -0.33 -0.45
7539 || orf19.855 || || || Ortholog of C. dubliniensis CD36 : Cd36_18340, Candida tenuis NRRL Y-1498 : CANTEDRAFT_124631, Debaryomyces hansenii CBS767 : DEHA2D04356g and Pichia stipitis Pignal : PICST_34839 || 1 0.67 -0.21 0.56 1.13 -0.39 0.22 -0.45 -0.16 0.82 -0.82 -1.09 -0.44 -0.21 -0.77 -0.72 -1.11
7540 || orf19.855 || || || Ortholog of C. dubliniensis CD36 : Cd36_18340, Candida tenuis NRRL Y-1498 : CANTEDRAFT_124631, Debaryomyces hansenii CBS767 : DEHA2D04356g and Pichia stipitis Pignal : PICST_34839 || 1 0.55 -0.24 0.67 1.11 -0.59 0.42 -0.57 -0.54 0.87 -0.51 -0.85 -0.30 -0.41 -0.01 -0.66 -0.64
7541 || orf19.3546 || PEX2 || || Ortholog(s) have ubiquitin-protein ligase activity, role in fatty acid metabolic process, protein import into peroxisome matrix and peroxisomal membrane localization || 1 0.46 -0.40 0.59 0.51 -0.29 0.09 -0.39 -0.29 0.54 -0.24 -0.50 -0.28 -0.02 -0.23 -0.46
7542 || orf19.1840 || || || Predicted lipid-binding ER protein; involved in ER-plasma membrane tethering; Spider biofilm induced || 1 0.64 -0.07 0.26 0.77 -0.04 0.12 -0.47 -0.57 0.36 -0.49 -0.81 -0.27 0.07 -0.22 0.06 -0.86
7543 || orf19.1800 || || || Protein of unknown function; Spider biofilm induced || 1 0.10 0.28 0.76 0.58 0.05 0.51 -0.17 -0.16 0.15 -0.78 -0.42 -0.63 0.24 0.05 -0.05 -0.46
7544 || orf19.1759 || PHO23 || || Ortholog(s) have methylated histone residue binding activity || 1 -0.05 0.19 1.57 0.83 0.07 0.22 -0.29 -0.63 0.05 -0.44 -0.28 -0.20 0.38 -0.13 0.30 0.43
7545 || orf19.936 || || || Ortholog of C. dubliniensis CD36 : Cd36_50530, C. parapsilosis CDC317 : CPAR2_303990, Candida tenuis NRRL Y-1498 : CANTEDRAFT_107934 and Pichia stipitis Pignal : PICST_63283 || 1 0.05 0.30 1.71 0.79 0.17 0.72 -0.58 -0.65 0.18 -0.55 -0.41 -0.33 0.16 -0.47 0.13 0.13
7546 || orf19.2857 || || || Ortholog(s) have ATP-dependent DNA helicase activity || 1 -0.44 0.13 1.26 0.52 0.17 0.17 -0.39 -0.42 0.24 -0.25 -0.42 -0.06 0.02 -0.41 0.20 -0.04
7547 || orf19.113 || CIP1 || || Possible oxidoreductase; transcript induced by cadmium but not other heavy metals, heat shock, yeast-hypha switch, oxidative stress (via Cap1), or macrophage interaction; stationary phase enriched protein; Spider biofilm induced || 1 0.23 0.18 1.13 1.12 -0.30 -0.00 -0.33 -0.33 0.59 -0.22 -0.69 -0.18 -0.42 -0.30 0.17 -0.89
7548 || orf19.6048 || || || Protein of unknown function; Spider biofilm induced || 1 0.08 0.09 0.80 1.09 -0.13 -0.02 -0.33 -0.06 0.33 -0.50 -0.68 -0.45 -0.01 -0.26 -0.03 -0.89
7549 || orf19.6753 || || || Protein with a predicted RING-type zinc finger; possibly an essential gene, disruptants not obtained by UAU1 method || 1 -0.11 -0.15 0.66 0.58 -0.18 -0.11 -0.19 -0.33 -0.08 -0.37 -0.29 0.01 -0.05 -0.17 0.05 -0.36
7550 || orf19.5660 || || || Ortholog(s) have ubiquitin-protein ligase activity, role in protein import into peroxisome matrix, protein ubiquitination and endoplasmic reticulum, peroxisomal membrane localization || 1 0.26 0.16 0.86 0.74 -0.17 -0.30 -0.13 -0.25 -0.12 -0.45 -0.23 -0.23 -0.12 0.01 -0.21 -0.47
7551 || orf19.1122 || || || Protein of unknown function; induced by alpha pheromone in SpiderM medium; Spider biofilm induced || 1 0.00 0.25 1.03 1.02 0.09 -0.17 -0.38 -0.05 -0.12 -0.76 -0.22 -0.05 -0.12 -0.21 -0.13 -0.30
7552 || orf19.5433 || || || Ortholog(s) have protein binding involved in protein folding activity, role in mitochondrial respiratory chain complex III assembly and mitochondrial matrix localization || 1 0.25 0.22 1.44 1.27 -0.16 -0.02 -0.06 -0.28 0.15 -0.67 -0.53 -0.35 0.45 -0.30 0.34 -0.50
7553 || orf19.2761 || || || Putative glycosylphosphatidylinositol (GPI) anchor assembly protein; transposon insertion causes decreased colony wrinkling but does not block true hyphal growth; induced by nitric oxide independent of Yhb1p || 1 0.04 0.20 1.20 0.87 0.16 -0.14 0.01 -0.34 -0.01 -0.67 -0.70 -0.20 0.28 -0.37 0.41 -0.04
7554 || orf19.2743 || || || Ortholog(s) have RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription, more || 1 -0.32 -0.30 0.92 0.89 0.09 0.43 -0.41 -0.01 0.45 -0.68 -0.29 -0.15 -0.19 -0.22 -0.22 0.11
7555 || orf19.6449 || || || Ortholog of C. dubliniensis CD36 : Cd36_34310 || 1 0.10 -0.09 1.89 1.41 0.18 1.25 -0.56 0.28 0.69 -0.77 -0.65 -0.32 -0.31 -0.47 -0.68 -0.02
7556 || orf19.4741 || || || Protein of unknown function; C. albicans- and C. dubliniensis specific gene; rat catheter biofilm repressed || 1 -0.39 -0.15 1.09 1.98 0.46 1.39 -0.38 -0.00 0.09 -0.72 -0.71 -0.39 -0.62 -0.10 -0.56 -0.40
7557 || orf19.3107 || || || Ortholog of C. dubliniensis CD36 : Cd36_46490, Pichia stipitis Pignal : PICST_33598, Spathaspora passalidarum NRRL Y-27907 : spas_CGOB_00037 and Candida tropicalis MYA-3404 : CTRG_03758 || 1 -0.35 -0.24 1.32 1.38 0.46 0.80 -0.70 -0.36 0.20 -0.34 -0.90 -0.56 -0.61 -0.63 -0.72 -0.87
7558 || orf19.3427 || || || Ortholog of Candida albicans WO-1 : CAWG_05207 || 1 -0.15 -0.01 1.13 1.03 -0.00 0.49 -0.70 -0.94 0.26 -0.55 -0.39 -0.48 -0.46 -0.14 -0.64 -0.56
7559 || orf19.1523 || FMO1 || || Putative oxidoreductase; mutation confers hypersensitivity to toxic ergosterol analog, and to amphotericin B || 1 0.01 -0.16 1.51 1.42 0.23 1.11 -0.08 -0.86 0.08 -0.58 -1.18 -0.67 -0.25 0.08 -0.32 -0.40
7560 || orf19.3736 || KAR4 || || Transcription factor; required for gene regulation in response to pheromones; ortholog of S. cerevisiae Kar4; role in karyogamy; opaque-specific, a-specific; induced by alpha factor || 1 0.07 0.57 1.49 1.53 -0.19 0.37 -0.19 -0.34 0.02 -0.55 -0.51 -0.21 -0.10 -0.52 -0.12 0.20
7561 || orf19.7245 || || || Ortholog(s) have tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity, role in mitochondrial tRNA thio-modification and mitochondrion localization || 1 -0.04 0.06 1.22 1.10 0.10 0.47 -0.04 -0.37 0.26 -0.42 -0.22 -0.14 -0.02 -0.17 -0.05 -0.10
7562 || orf19.6720 || || || P-Loop domain-containing protein of unknown function; transposon mutation affects filamentous growth; Spider biofilm induced || 1 0.05 0.29 1.53 1.26 -0.01 0.56 0.01 -0.40 0.21 -0.61 -0.50 -0.34 0.05 0.16 -0.04 -0.09
7563 || orf19.693 || || || Protein of unknown function; Spider biofilm induced; rat catheter biofilm repressed || 1 -0.11 -0.00 1.74 1.86 -0.28 0.74 -0.41 -0.23 0.48 -0.45 -1.00 -0.46 -0.08 -0.42 -0.01 -0.57
7564 || orf19.4361 || IFF3 || || Putative GPI-anchored protein || 1 0.06 -0.14 0.86 0.91 -0.25 0.82 -0.31 -0.13 0.22 -0.35 -0.61 -0.20 -0.32 -0.11 -0.33 0.30
7565 || orf19.1450 || || || Ortholog of C. dubliniensis CD36 : Cd36_16320, Candida tropicalis MYA-3404 : CTRG_01238 and Candida albicans WO-1 : CAWG_03918 || 1 -0.15 -0.21 0.82 1.02 -0.10 0.56 -0.40 -0.22 0.22 -0.20 -0.65 -0.00 -0.21 -0.42 -0.29 -0.01
7566 || orf19.693 || || || Protein of unknown function; Spider biofilm induced; rat catheter biofilm repressed || 1 -0.06 -0.19 1.17 1.12 -0.27 0.83 -0.90 -0.89 0.38 -0.35 -0.87 -0.12 -0.06 -0.25 -0.23 -0.11
7567 || orf19.693 || || || Protein of unknown function; Spider biofilm induced; rat catheter biofilm repressed || 1 -0.02 -0.09 1.24 1.27 -0.22 0.92 -0.94 -0.91 0.52 -0.35 -0.85 -0.29 0.04 -0.26 -0.32 -0.11
7568 || orf19.7209 || || || Putative Rho GDP dissociation inhibitor; induced by nitric oxide independent of Yhb1p || 1 -0.17 0.24 1.14 1.46 -0.13 1.00 -0.65 -0.65 0.23 -0.01 -0.35 -0.52 -0.26 0.05 -0.59 -0.28
7569 || orf19.5304 || || || Ortholog of C. dubliniensis CD36 : Cd36_43800 and Candida albicans WO-1 : CAWG_03395 || 1 -0.30 -0.26 1.94 1.59 -0.65 1.20 -0.40 -0.70 0.43 -0.22 -0.50 -0.29 -0.07 0.14 -0.69 -0.09
7570 || orf19.377 || PHR3 || || Putative beta-1,3-glucanosyltransferase with similarity to the A. fumigatus GEL family; fungal-specific (no human or murine homolog); possibly an essential gene, disruptants not obtained by UAU1 method || 1 -0.43 -0.21 1.79 1.52 0.12 0.99 -0.56 -0.44 0.43 -0.42 -0.55 -0.35 0.30 -0.32 -0.79 -0.21
7571 || orf19.7480 || || || Putative protein of unknown function; transcript is upregulated in clinical isolates from HIV+ patients with oral candidiasis || 1 -0.41 -0.50 1.02 0.79 -0.02 0.17 -0.27 -0.35 0.33 -0.32 -0.52 -0.15 -0.23 -0.12 -0.32 -0.30
7572 || orf19.4680 || || || Possile protease; mutation confers hypersensitivity to toxic ergosterol analog || 1 -0.66 -0.52 1.80 1.22 -0.55 0.20 -0.46 -0.66 0.71 -0.42 -1.01 -0.30 -0.33 -0.09 -0.53 0.13
7573 || orf19.6911 || || || Ortholog of Candida albicans WO-1 : CAWG_05482 || 1 -0.26 -0.03 1.51 1.07 -0.40 0.48 -0.36 -0.58 0.38 -0.43 -0.96 -0.17 -0.32 -0.29 -0.51 -0.34
7574 || orf19.693 || || || Protein of unknown function; Spider biofilm induced; rat catheter biofilm repressed || 1 -0.35 -0.28 1.68 1.32 -0.35 0.40 -0.50 -0.85 0.34 -0.50 -1.06 -0.49 -0.27 -0.31 -0.01 -0.26
7575 || orf19.780 || DUR1,2 || || Urea amidolyase; hydrolyzes urea to CO2; use of urea as N source and for hyphal switch in macrophage; regulated by Nrg1/Hap43; required for virulence; promotes mouse kidney and brain colonization; rat catheter and flow model biofilm induced || 1 -0.61 -0.51 1.31 1.23 -0.66 0.00 -0.53 -0.96 0.46 -1.02 -0.75 -0.57 -0.17 -0.12 -0.38 0.03
7576 || orf19.24 || RTA2 || || Flippase; sphingolipid long chain base release; mediates calcineurin-dependent resistance to azoles; stress-associate; Plc1, Ca2+, calcineurin-regulated; ketoconazole, caspofungin induced; Spider biofilm induced; flow biofilm repressed || 1 -0.34 -0.55 1.28 1.63 -0.62 0.56 -0.75 -1.01 0.25 -1.28 -1.31 -0.51 -0.59 -1.26 -0.10 -0.23
7577 || orf19.5866 || || || Ortholog of Candida albicans WO-1 : CAWG_02737 || 1 0.04 -0.04 1.35 1.68 0.08 0.35 -0.89 -0.57 0.06 -0.93 -0.59 -0.71 -0.12 -1.05 -0.54 0.02
7578 || orf19.2868 || || || Protein of unknown function; induced by alpha pheromone in SpiderM medium || 1 0.13 -0.07 1.03 0.52 -0.25 0.34 -0.44 -0.30 -0.06 -0.62 -0.66 -0.26 -0.09 -0.46 -0.38 0.00
7579 || orf19.6911 || || || Ortholog of Candida albicans WO-1 : CAWG_05482 || 1 -0.05 0.09 0.96 0.87 -0.32 0.14 -0.48 -0.26 -0.01 -0.97 -0.69 -0.08 -0.03 -0.71 -0.57 0.27
7580 || orf19.2674 || || || Putative transcription factor with zinc finger DNA-binding motif; Hap43p-repressed gene || 1 -0.24 -0.11 1.04 1.06 -0.28 -0.15 -0.28 -0.26 -0.17 -0.66 -0.44 -0.36 -0.15 -0.69 -0.34 0.17
7581 || orf19.3238 || || || Ortholog of Candida albicans WO-1 : CAWG_01469 || 1 -0.39 -0.03 1.27 1.45 -0.36 0.01 -0.28 -0.29 -0.24 -0.67 -1.02 -0.24 -0.24 -0.90 -0.68 -0.33
7582 || orf19.4821 || LIP1 || || Secreted lipase, member of a lipase gene family whose members are expressed differentially in response to carbon source and during infection; may have a role in nutrition and/or in creating an acidic microenvironment || 1 -0.30 0.07 1.59 1.16 -0.36 0.08 -0.47 -0.60 -0.26 -0.45 -0.91 -0.33 -0.25 -0.51 -0.57 -0.44
7583 || orf19.2025 || || || Dubious open reading frame || 1 -0.21 -0.08 1.19 0.84 -0.34 0.27 -0.63 -0.60 -0.06 -0.64 -0.86 -0.37 -0.27 -0.62 -0.60 -0.24
7584 || orf19.3232 || || || Putative transporter; mutation confers hypersensitivity to toxic ergosterol analog; fungal-specific (no human or murine homolog) || 1 -0.00 0.23 1.27 1.00 -0.47 -0.25 -0.47 -0.45 0.00 -0.40 -0.73 -0.36 -0.10 -0.24 -0.66 -0.26
7585 || orf19.7167 || || || Putative adhesin-like protein || 1 -0.04 0.07 1.10 1.00 -0.29 0.15 -0.17 -0.24 0.23 -0.18 -0.58 -0.44 -0.16 0.03 -0.53 -0.57
7586 || orf19.3898 || || || Ortholog(s) have SNAP receptor activity, role in endocytosis, vesicle fusion and Golgi apparatus, SNARE complex, endoplasmic reticulum, endosome, trans-Golgi network localization || 1 -0.09 0.47 0.88 0.77 0.08 0.51 -0.16 -0.38 0.41 -0.10 -0.22 -0.29 0.24 -0.14 -0.44 -0.13
7587 || orf19.5461 || || || Ortholog of Candida albicans WO-1 : CAWG_02350 || 1 0.21 0.71 0.84 0.91 -0.10 0.72 -0.50 -0.57 0.18 -0.35 -0.35 -0.33 0.07 0.03 -0.69 -0.51
7588 || orf19.2859 || SRP40 || || Putative chaperone of small nucleolar ribonucleoprotein particles; macrophage/pseudohyphal-induced; rat catheter biofilm induced || 1 -0.08 0.05 1.01 0.60 0.14 0.76 -0.92 -0.89 0.22 -0.12 -0.82 -0.94 0.23 -0.08 -0.44 -0.68
7589 || orf19.5678 || || || Has domain(s) with predicted role in peptidyl-diphthamide biosynthetic process from peptidyl-histidine and cytoplasm localization || 1 0.08 0.01 0.74 0.46 -0.02 0.65 -0.51 -0.50 0.16 -0.43 -0.56 -0.81 0.17 -0.45 -0.20 -0.74
7590 || orf19.4368 || || || Has domain(s) with predicted hydrolase activity and role in cellular process || 1 0.25 0.20 0.99 0.78 0.26 0.48 -0.42 -0.80 -0.08 -0.90 -0.86 -0.76 0.09 -0.34 -0.07 -0.34
7591 || orf19.4504 || || || Has domain(s) with predicted oxidoreductase activity, transferase activity, transferring acyl groups other than amino-acyl groups, zinc ion binding activity and role in oxidation-reduction process || 1 0.14 0.14 1.37 1.18 0.48 0.63 -0.71 -0.68 -0.36 -0.99 -1.76 -0.89 0.58 -0.58 -0.65 -0.93
7592 || orf19.10712 || MTLALPHA1 || || Master regulator (activator) of alpha mating type; gene of the MTLalpha (Mating Type Like) locus; ortholog of S. cerevisiae Alpha1p; a/alpha mating type may increase virulence, offers competitive advantage || 1 0.17 0.17 1.09 0.96 0.29 0.45 -0.56 -0.54 0.16 -0.46 -0.95 -0.33 0.39 -0.52 -0.52 -0.65
7593 || orf19.1728 || || || Ortholog of C. dubliniensis CD36 : Cd36_81190, C. parapsilosis CDC317 : CPAR2_503840, Debaryomyces hansenii CBS767 : DEHA2A09042g and Pichia stipitis Pignal : PICST_42519 || 1 -0.17 0.18 0.71 0.37 0.21 0.39 -0.33 -0.46 0.23 -0.75 -0.61 -0.26 0.18 -0.33 -0.49 -0.71
7594 || orf19.3868 || || || Dubious open reading frame || 1 -0.20 0.15 0.94 0.62 0.15 0.35 -0.56 -0.57 0.38 -0.59 -0.87 -0.43 0.14 -0.33 -0.60 -0.71
7595 || orf19.7464 || || || Putative subtilisin-family protease; mutation confers hypersensitivity to toxic ergosterol analog || 1 -0.27 0.30 1.50 1.00 -0.29 0.56 -0.54 -0.71 0.17 -0.71 -1.05 -0.46 0.09 -0.54 -0.93 -0.78
7596 || orf19.3427 || || || Ortholog of Candida albicans WO-1 : CAWG_05207 || 1 -0.23 -0.11 1.31 0.74 0.03 0.80 -0.75 -0.84 0.38 -0.69 -0.87 -0.66 0.11 -0.57 -0.69 -0.44
7597 || orf19.5986 || THI4 || || Thiamine biosynthetic enzyme precursor; repressed during the mating process; stationary phase enriched protein; Spider biofilm induced || 1 -0.23 -0.08 1.24 1.06 0.13 0.51 -1.01 -0.98 0.34 -0.71 -0.93 -0.34 -0.08 -0.67 -0.63 -0.44
7598 || orf19.693 || || || Protein of unknown function; Spider biofilm induced; rat catheter biofilm repressed || 1 -0.24 -0.00 1.01 1.13 -0.10 0.45 -0.80 -0.82 0.54 -0.37 -0.94 -0.17 0.14 -0.43 -0.48 -0.56
7599 || orf19.848 || PGA16 || || Putative GPI-anchored protein || 1 -0.20 -0.06 0.54 0.41 0.07 0.29 -0.67 -0.83 0.05 -0.44 -0.69 -0.40 -0.01 -0.44 -0.39 -0.48
7600 || orf19.1150 || || || GATA-like transcription factor; oral infection induced; mutant has reduced capacity to damage oral epithelial cells; regulated by Gcn2 and Gcn4; Spider biofilm induced || 1 -0.07 -0.04 0.65 0.79 0.19 0.25 -0.74 -0.91 0.49 -0.62 -0.81 -0.79 -0.14 -0.70 -0.42 -0.63
7601 || orf19.7629 || || || Ortholog(s) have Seh1-associated complex, cytosol, extrinsic to fungal-type vacuolar membrane, ribosome localization || 1 0.08 0.24 1.05 0.93 0.04 0.58 -0.90 -0.88 0.46 -0.40 -0.48 -0.21 0.10 -0.31 -0.34 -0.15
7602 || orf19.1227 || ZCF4 || || Putative Zn(II)2Cys6 transcription factor || 1 0.02 0.20 1.07 0.68 0.09 0.44 -0.79 -0.94 0.51 -0.42 -0.74 -0.54 0.28 -0.16 -0.37 -0.36
7603 || orf19.7153 || || || Putative exportin, member of the Exportin-T family; flow model biofilm repressed || 1 0.26 0.35 0.84 0.85 0.25 0.29 -0.80 -0.78 0.38 -0.21 -0.72 -0.28 0.20 -0.19 -0.10 -0.41
7604 || orf19.4955 || || || Ortholog(s) have role in ascospore wall assembly and endoplasmic reticulum, mitochondrion localization || 1 -0.26 0.10 0.98 0.72 0.29 0.36 -0.66 -0.76 0.74 -0.35 -0.78 -0.28 0.34 -0.08 -0.16 -0.23
7605 || orf19.7464 || || || Putative subtilisin-family protease; mutation confers hypersensitivity to toxic ergosterol analog || 1 -0.14 0.21 0.84 0.88 0.38 0.14 -0.82 -0.73 0.49 -0.71 -0.74 -0.11 0.30 -0.34 -0.14 -0.24
7606 || orf19.1057 || || || Ortholog of C. dubliniensis CD36 : Cd36_03980, C. parapsilosis CDC317 : CPAR2_107050, Candida tenuis NRRL Y-1498 : CANTEDRAFT_113999 and Debaryomyces hansenii CBS767 : DEHA2D12518g || 1 -0.14 0.24 0.54 0.44 0.19 0.00 -0.63 -0.73 0.30 -0.51 -0.70 -0.04 0.30 -0.20 -0.15 -0.19
7607 || orf19.7101 || || || Ortholog(s) have telomeric DNA binding activity, role in protein localization to chromosome, telomere maintenance via telomerase and ASTRA complex, nuclear telomere cap complex localization || 1 -0.19 0.05 0.57 0.50 0.12 0.21 -0.63 -0.68 0.11 -0.43 -0.52 -0.09 0.23 -0.06 -0.20 -0.28
7608 || orf19.6769 || || || Ortholog(s) have cytoplasm localization || 1 -0.26 0.11 0.68 0.56 0.00 0.07 -0.62 -0.67 0.25 -0.31 -0.59 0.04 0.28 -0.23 -0.41 -0.27
7609 || orf19.3012 || ARO80 || || Zn(II)2Cys6 transcription factor; transcriptional activator of aromatic amino acid catabolism; regulator of aromatic alcohol biosynthesis via the Ehrlich pathway; mutant is viable || 1 -0.14 -0.02 0.55 0.21 0.13 0.25 -0.36 -0.43 0.14 -0.49 -0.49 0.14 0.19 -0.37 -0.06 -0.42
7610 || orf19.3158 || || || Ortholog(s) have cytoplasm localization || 1 -0.15 -0.05 0.56 0.55 0.06 0.24 -0.49 -0.37 -0.07 -0.69 -0.43 -0.10 0.18 -0.55 -0.29 -0.45
7611 || orf19.5046 || RAM1 || || Protein that acts in prenylation; transcription is alpha-factor induced; regulated in response to lovastatin and fluconazole; Hap43p-repressed gene || 1 -0.18 -0.01 0.39 0.45 -0.12 0.33 -0.67 -0.58 -0.19 -0.62 -0.47 0.19 0.16 -0.36 -0.24 -0.23
7612 || orf19.2783 || PIR32 || || Cell wall protein, putative structural component of the cell wall; mutation leads to increased chitin content, increased virulence and resistance to stresses; macrophage-induced gene || 1 -0.14 0.07 0.74 0.81 -0.19 0.35 -0.74 -0.84 -0.21 -0.89 -0.92 0.02 0.07 -0.70 -0.52 -0.37
7613 || orf19.750 || || || Protein of unknown function; exogenously expressed protein is a substrate for Kex2p processing in vitro || 1 -0.01 -0.08 0.93 0.64 -0.02 0.76 -0.49 -1.03 -0.10 -0.87 -0.76 0.11 0.18 -0.53 -0.68 -0.28
7614 || orf19.3885 || || || Has domain(s) with predicted N-acetyltransferase activity; highly induced during chlamydospore formation in both C. albicans and C. dubliniensis || 1 -0.02 0.42 0.80 0.49 0.23 -0.11 -0.49 -0.67 0.32 -0.48 -0.74 -0.11 0.51 -0.18 -0.32 -0.32
7615 || orf19.7051 || || || Maf-like protein; rat catheter biofilm induced || 1 0.01 0.32 0.57 0.83 0.40 0.02 -0.52 -0.55 0.33 -0.52 -0.62 0.04 0.61 -0.32 -0.14 -0.05
7616 || orf19.4247 || || || Protein of unknown function; rat catheter and Spider biofilm repressed || 1 -0.02 0.38 0.69 0.92 0.38 0.23 -0.53 -0.52 0.34 -0.29 -0.46 -0.26 0.29 -0.13 -0.07 -0.08
7617 || orf19.1920 || || || Ortholog of C. dubliniensis CD36 : Cd36_15040 || 1 0.06 0.60 0.63 1.33 0.43 0.55 -0.54 -0.63 0.76 -0.77 -0.68 -0.40 0.39 -1.12 -0.64 -0.83
7618 || orf19.936 || || || Ortholog of C. dubliniensis CD36 : Cd36_50530, C. parapsilosis CDC317 : CPAR2_303990, Candida tenuis NRRL Y-1498 : CANTEDRAFT_107934 and Pichia stipitis Pignal : PICST_63283 || 1 0.38 0.62 0.66 0.91 0.60 0.14 -0.33 -0.44 0.58 -0.38 -0.78 -0.13 0.68 -0.50 -0.55 -0.87
7619 || orf19.5854.1 || || || Has domain(s) with predicted ATP binding, ATPase activity || 1 0.10 0.42 0.79 0.81 0.37 0.35 -0.08 -0.13 0.15 -0.49 -0.27 -0.28 0.50 -0.25 -0.05 -0.67
7620 || orf19.1942 || SGE1 || || Putative multidrug resistance factor; induced in low iron; regulated by Sef1, Sfu1, and Hap43 || 1 0.03 0.34 0.66 1.10 0.40 0.27 -0.31 -0.48 0.45 -0.57 -0.54 -0.21 0.39 -0.40 0.00 -0.75
7621 || orf19.7495 || || || Protein with NADPH oxidoreductase containing flavin mononucleotide (FMN) domain; induced by nitric oxide || 1 0.30 0.79 0.90 1.57 0.70 0.61 -0.35 -0.52 0.63 -0.74 -0.53 -0.32 0.65 -0.28 -0.13 -0.67
7622 || orf19.3627 || || || Ortholog of C. dubliniensis CD36 : Cd36_22640, C. parapsilosis CDC317 : CPAR2_406910, Candida tenuis NRRL Y-1498 : CANTEDRAFT_104937 and Debaryomyces hansenii CBS767 : DEHA2D02706g || 1 0.04 0.54 0.70 1.04 0.63 0.37 -0.38 -0.31 0.53 -0.22 -0.52 -0.25 0.54 -0.22 -0.08 -0.70
7623 || orf19.5862 || AFP99 || || Protein related to arginases; downregulated upon adherence to polystyrene; regulated by Gcn2p and Gcn4p || 1 0.33 0.79 1.03 1.16 0.58 0.64 -0.34 -0.44 0.70 -0.27 -0.40 0.13 0.68 -0.42 -0.28 -0.45
7624 || orf19.4955 || || || Ortholog(s) have role in ascospore wall assembly and endoplasmic reticulum, mitochondrion localization || 1 -0.03 0.30 0.99 0.90 0.49 0.47 -0.24 -0.17 0.39 -0.43 -0.42 -0.17 0.49 -0.33 0.03 -0.30
7625 || orf19.4720 || CTR2 || || Putative low-affinity copper transporter of the vacuolar membrane; induced by nitric oxide; clade-associated gene expression; rat catheter and flow model biofilm induced || 1 0.15 0.37 0.80 0.55 0.27 0.54 -0.31 -0.29 0.36 -0.36 -0.41 -0.03 0.31 -0.32 -0.05 -0.19
7626 || orf19.3888.2 || || || Dubious open reading frame || 1 0.18 0.44 1.59 0.97 0.42 0.78 -0.45 -0.49 0.88 -0.59 -0.66 0.00 0.47 -0.48 -0.36 -0.96
7627 || orf19.3643 || || || Protein of unknown function; Hap43-repressed gene || 1 0.15 0.64 1.10 0.70 0.79 0.79 -0.39 -0.55 0.98 -0.49 -0.60 -0.24 0.83 0.03 -0.34 -0.64
7628 || orf19.4872 || || || Protein of unknown function; induced by Mnl1 under weak acid stress; Hap43-induced; mutant is viable || 1 0.31 0.62 1.09 1.43 0.98 0.75 -0.29 -0.44 1.11 -0.63 -0.56 0.06 0.99 0.09 -0.39 -0.43
7629 || orf19.2033 || PGA19 || || Putative GPI-anchored protein; macrophage-induced gene; mutants are viable || 1 0.03 0.79 0.98 1.22 0.55 0.86 -0.53 -0.54 1.07 -0.44 -0.83 -0.55 0.80 -0.47 -0.66 -0.53
7630 || orf19.376 || || || Protein of unknown function; Hap43-repressed; Spider biofilm induced || 1 0.57 0.54 1.62 1.62 0.34 0.04 -0.74 -0.88 0.68 -0.49 -0.70 -0.44 0.58 -0.44 -0.10 -0.46
7631 || orf19.2285 || || || Protein of unknown function; transcription induced by benomyl treatment || 1 0.19 0.31 0.82 0.76 0.06 -0.06 -0.29 -0.27 0.31 -0.20 -0.55 -0.42 0.40 -0.29 -0.23 -0.28
7632 || orf19.689 || PLB1 || || Phospholipase B; host cell penetration and virulence in mouse systemic infection; Hog1-induced; signal sequence, N-glycosylation, and Tyr phosphorylation site; induced in fluconazole-resistant strains; rat catheter biofilm repressed || 1 0.39 0.71 1.42 1.25 0.53 0.32 -0.45 -0.38 0.79 -0.60 -0.73 -0.87 0.54 -0.36 -0.44 -0.67
7633 || orf19.4227 || || || Ortholog of C. parapsilosis CDC317 : CPAR2_100400, C. dubliniensis CD36 : Cd36_52020, Debaryomyces hansenii CBS767 : DEHA2F14278g and Candida orthopsilosis Co 90-125 : CORT_0F00500 || 1 0.11 0.42 0.87 0.73 0.55 -0.00 -0.30 -0.38 0.47 -0.50 -0.56 -0.17 0.29 -0.20 -0.38 -0.40
7634 || orf19.7125 || || || Protein of unknown function; Spider biofilm repressed || 1 -0.05 0.44 0.71 0.83 0.02 -0.05 -0.55 -0.47 0.47 -0.35 -0.55 -0.32 0.39 -0.26 -0.37 -0.56
7635 || orf19.4481 || MFALPHA || || Alpha factor mating pheromone precursor; three copies of pheromone that are proteolytically processed by Kex2p and possibly by Orf19.5851p; required for alpha cells to mate; expressed specifically in opaque phase MTLalpha/MTLalpha cells || 1 0.29 0.56 1.24 1.01 0.35 0.32 -0.32 -0.35 0.90 -0.49 -0.61 -0.49 0.58 -1.02 -0.35 -1.24
7636 || orf19.3735 || || || Protein of unknown function; induced by alpha pheromone in SpiderM medium || 1 0.25 0.09 1.13 0.87 0.00 0.29 -0.37 -0.13 0.60 -0.41 -0.49 -0.27 0.43 -0.46 -0.10 -0.85
7637 || orf19.1824 || PGA50 || || Putative GPI-anchored protein; adhesin-like protein || 1 0.11 0.09 1.05 1.11 0.38 0.11 -0.58 -0.21 0.46 -0.37 -0.64 -0.23 0.37 -0.43 -0.50 -1.18
7638 || orf19.850 || || || Ortholog(s) have protein-N-terminal asparagine amidohydrolase activity, protein-N-terminal glutamine amidohydrolase activity and role in cellular protein modification process, protein catabolic process || 1 -0.17 0.26 1.09 0.78 0.07 0.00 -0.35 -0.43 0.29 -0.39 -0.58 -0.47 0.19 -0.33 -0.20 -0.68
7639 || orf19.1124 || || || Protein of unknown function; flow model biofilm induced; Spider biofilm induced || 1 0.01 0.18 1.35 1.02 -0.09 0.37 -0.53 -0.49 0.33 -0.21 -0.71 -0.21 0.13 -0.84 -0.42 -0.77
7640 || orf19.6788 || || || Protein with a predicted role in cotranslational protein targeting to membrane; induced during chlamydospore formation in both C. albicans and C. dubliniensis || 1 -0.08 0.08 0.85 0.96 0.12 0.12 -0.34 -0.22 0.18 -0.26 -0.59 -0.20 0.05 -0.51 -0.15 -0.65
7641 || orf19.4955 || || || Ortholog(s) have role in ascospore wall assembly and endoplasmic reticulum, mitochondrion localization || 1 -0.04 -0.01 0.76 0.81 0.15 0.16 -0.30 -0.27 0.11 -0.43 -0.51 -0.28 0.02 -0.70 -0.13 -0.27
7642 || orf19.2033 || PGA19 || || Putative GPI-anchored protein; macrophage-induced gene; mutants are viable || 1 0.10 0.10 1.04 1.55 -0.02 0.45 0.07 -0.32 -0.11 -1.04 -0.19 -0.05 0.41 -0.95 0.02 -0.39
7643 || orf19.5954 || || || Ortholog(s) have enzyme activator activity, role in ascospore wall assembly, meiosis I, positive regulation of protein catabolic process and anaphase-promoting complex localization || 1 0.13 0.14 0.82 1.32 0.13 0.06 -0.20 -0.03 -0.22 -0.54 -0.44 -0.01 0.25 -0.47 -0.28 -0.07
7644 || orf19.3105 || || || Putative cytochrome P450 protein; possibly an essential gene, disruptants not obtained by UAU1 method || 1 0.09 0.26 1.01 1.22 0.44 0.42 -0.17 -0.32 -0.28 -0.69 -0.61 -0.18 0.37 -0.64 -0.02 -0.37
7645 || orf19.115 || || || Ortholog of Candida tropicalis MYA-3404 : CTRG_02973 and Candida albicans WO-1 : CAWG_05252 || 1 0.24 0.40 0.92 1.29 0.34 0.30 -0.31 -0.31 0.09 -0.60 -0.53 -0.12 0.33 -0.41 -0.26 -0.23
7646 || orf19.801 || TBF1 || || Essential transcription factor; induces ribosomal protein genes and the rDNA locus; acts with Cbf1 at subset of promoters; recruits Fhl1 and Ifh1 to promoters; role is analogous to that of S. cerevisiae Rap1; Spider biofilm induced || 1 0.19 0.37 1.00 1.71 0.27 0.50 -0.35 -0.36 0.30 -0.70 -0.51 -0.12 0.25 -0.83 -0.03 -0.60
7647 || orf19.6182 || ZCF34 || || Zn(II)2Cys6 transcription factor involved in regulation of multidrug resistance via control of CDR1 expression; mutants display decreased colonization of mouse kidneys; required for yeast cell adherence to silicone substrate || 1 0.41 0.26 1.38 1.32 0.49 0.48 -0.13 -0.17 0.32 -0.65 -0.41 0.25 0.22 -0.66 -0.22 -0.33
7648 || orf19.692 || || || Protein of unknown function; Hap43-repressed gene; rat catheter and Spider biofilm induced || 1 -0.18 0.26 1.59 1.75 0.47 0.17 -0.42 -0.45 0.33 -0.73 -0.49 0.18 0.23 -0.41 -0.08 -0.54
7649 || orf19.3758 || || || Ortholog(s) have fungal-type vacuole membrane localization || 1 0.06 0.04 0.78 0.85 0.37 0.26 -0.35 -0.29 -0.09 -0.38 -0.27 0.01 -0.11 -0.09 -0.20 -0.26
7650 || orf19.570 || IFF8 || || Putative GPI-anchored adhesin-like protein; decreased transcription is observed in an azole-resistant strain that overexpresses MDR1 || 1 0.25 0.30 1.43 1.28 0.13 1.27 -0.92 -0.39 -0.29 -0.28 -1.10 0.01 0.42 -0.46 -0.51 0.55
7651 || orf19.3049 || || || Ortholog(s) have protein kinase activity, role in activation of bipolar cell growth, ascospore wall assembly, protein phosphorylation and cell division site, cytosol, nucleus, prospore membrane localization || 1 -0.01 -0.00 0.75 0.96 -0.08 0.47 -0.26 -0.01 0.31 -0.47 -0.51 0.05 0.28 -0.29 -0.25 0.29
7652 || orf19.3427 || || || Ortholog of Candida albicans WO-1 : CAWG_05207 || 1 -0.29 0.20 1.53 1.36 0.17 0.27 -0.63 -0.56 0.57 -0.33 -0.59 0.14 0.44 -0.39 -0.37 0.08
7653 || orf19.4391 || || || Ortholog of C. dubliniensis CD36 : Cd36_28730, Candida tropicalis MYA-3404 : CTRG_00749 and Candida albicans WO-1 : CAWG_01683 || 1 0.26 0.29 1.56 1.50 0.52 1.02 -0.78 -0.57 0.57 -0.33 -0.71 0.26 0.28 -0.75 -0.66 0.13
7654 || orf19.4955 || || || Ortholog(s) have role in ascospore wall assembly and endoplasmic reticulum, mitochondrion localization || 1 0.12 0.18 1.24 1.04 0.19 0.53 -0.24 0.05 0.42 -0.12 -0.32 0.38 0.00 -0.31 -0.02 -0.09
7655 || orf19.5308 || || || Protein of unknown function; induced by Rgt1 || 1 0.09 0.12 0.97 0.93 -0.04 0.52 -0.28 -0.14 0.19 0.13 -0.42 0.16 -0.14 -0.32 -0.14 -0.21
7656 || orf19.4057 || || || Ortholog of Candida albicans WO-1 : CAWG_00885 || 1 0.32 0.27 1.46 1.37 0.25 1.36 -0.88 -0.24 0.10 -0.27 -0.29 0.19 -0.03 -0.94 -0.06 0.42
7657 || orf19.4822 || LIP10 || || Secreted lipase, member of a lipase gene family whose members are expressed differentially in response to carbon source and during infection; may have a role in nutrition and/or in creating an acidic microenvironment || 1 0.02 0.13 0.82 1.15 -0.02 0.91 -0.76 -0.40 0.26 -0.43 -0.35 0.05 -0.27 -0.67 -0.61 0.28
7658 || orf19.4712 || FGR6-3 || || Protein lacking an ortholog in S. cerevisiae; member of a family encoded by FGR6-related genes in the RB2 repeat sequence; transposon mutation affects filamentous growth || 1 0.07 0.19 0.75 0.42 0.10 0.38 -0.76 -0.23 0.47 -0.31 -0.21 -0.28 0.13 -0.41 -0.12 0.14
7659 || orf19.7209 || || || Putative Rho GDP dissociation inhibitor; induced by nitric oxide independent of Yhb1p || 1 0.31 0.16 1.71 1.43 0.18 0.36 -0.97 -0.88 0.63 -0.55 -0.24 -0.66 0.10 -0.62 -0.50 -0.04
7660 || orf19.34 || GIT1 || || Glycerophosphoinositol permease; involved in utilization of glycerophosphoinositol as a phosphate source; Rim101-repressed; virulence-group-correlated expression || 1 0.73 0.63 1.74 1.85 0.34 1.63 -0.71 -0.91 0.37 -1.35 -0.41 -0.95 0.09 -1.11 -0.33 0.20
7661 || orf19.1257 || || || Ortholog of Candida albicans WO-1 : CAWG_03251 || 1 0.49 0.20 1.30 0.99 0.48 0.97 -0.76 -0.37 0.38 -0.92 -0.17 -0.19 0.36 -0.74 -0.23 0.02
7662 || orf19.7330 || || || Protein with a predicted heme oxygenase domain; Spider biofilm induced || 1 0.10 0.41 1.05 0.66 0.23 0.48 -0.42 -0.36 0.14 -0.93 -0.33 -0.14 0.27 -0.49 -0.19 0.02
7663 || orf19.3107 || || || Ortholog of C. dubliniensis CD36 : Cd36_46490, Pichia stipitis Pignal : PICST_33598, Spathaspora passalidarum NRRL Y-27907 : spas_CGOB_00037 and Candida tropicalis MYA-3404 : CTRG_03758 || 1 0.78 1.01 1.47 1.60 0.70 0.92 -0.48 -0.62 0.37 -0.95 -0.63 -0.33 0.62 -0.57 -0.26 -0.28
7664 || orf19.5672 || MEP2 || || Ammonium permease and regulator of nitrogen starvation-induced filamentation; 11 predicted transmembrane regions; in low nitrogen cytoplasmic C-terminus activates Ras/cAMP and MAPK signal transduction pathways to induce filamentation || 1 0.68 0.86 1.27 1.31 0.44 0.76 -0.64 -1.04 0.61 -1.01 -0.97 -0.38 0.81 -0.55 -0.46 0.14
7665 || orf19.3261 || ATO9 || || Putative fungal-specific transmembrane protein || 1 0.46 0.43 1.03 1.25 0.18 0.64 -0.57 -0.65 0.35 -0.64 -0.28 -0.11 -0.14 -0.31 -0.25 -0.31
7666 || orf19.278 || || || Protein of unknown function; required for adhesion to abiotic substrate; Spider biofilm induced || 1 1.21 0.58 1.11 2.21 -0.09 0.61 -0.91 -0.90 0.57 -0.90 -0.77 0.39 0.01 -0.70 -0.18 -0.61
7667 || orf19.5657 || SWI1 || || Protein involved in transcription regulation; ortholog of S. cerevisiae Swi1p, which is a subunit of the SWI/SNF chromatin remodeling complex; interacts with Snf2p; SWI/SNF complex is essential for hyphal growth and virulence || 1 -0.02 0.01 0.52 0.73 0.26 0.18 -0.52 -0.27 0.20 -0.19 -0.17 0.25 0.28 -0.42 -0.28 -0.30
7668 || orf19.579 || FOL1 || || Putative dihydroneopterin aldolase (dihydro-6-hydroxymethylpterin pyrophosphokinase); fungal-specific (no human or murine homolog) || 1 -0.22 0.14 0.86 1.07 0.31 0.17 -0.85 -0.58 0.74 -0.22 -0.52 0.25 0.48 -0.25 -0.20 -0.53
7669 || orf19.1840 || || || Predicted lipid-binding ER protein; involved in ER-plasma membrane tethering; Spider biofilm induced || 1 -0.00 -0.05 0.40 0.85 -0.07 0.31 -0.43 -0.51 -0.00 -0.29 -0.56 0.02 0.06 -0.39 0.11 -0.44
7670 || orf19.3905 || MRV5 || || Planktonic growth-induced gene || 1 -0.07 0.50 0.74 1.64 0.05 0.37 -0.78 -0.93 0.35 -0.82 -1.02 -0.00 0.16 -1.02 -0.32 -0.60
7671 || orf19.5278 || || || Protein of unknown function; Spider biofilm induced || 1 -0.26 -0.01 0.42 1.33 -0.14 0.08 -0.63 -0.64 0.00 -0.58 -0.81 -0.25 -0.08 -0.92 -0.24 -0.96
7672 || orf19.1608 || || || Ortholog(s) have cytosol, nucleus localization || 1 -0.04 0.20 0.96 1.32 0.22 0.32 -0.43 -0.57 0.51 -0.54 -0.73 -0.37 0.28 -0.44 0.52 -0.70
7673 || orf19.3550 || SGO1 || || Component of the spindle checkpoint; cell-cycle regulated periodic mRNA expression || 1 -0.02 0.13 0.60 0.55 -0.07 0.12 -0.28 -0.31 -0.04 -0.37 -0.31 -0.18 0.39 0.02 -0.37 -0.52
7674 || orf19.4509 || || || Protein of unknown function || 1 0.06 0.10 1.18 0.96 0.53 0.60 -0.09 -0.29 0.19 -0.54 -0.69 -0.56 0.42 -0.17 -0.83 -0.84
7675 || orf19.138 || FIG1 || || S. cerevisiae Fig1 ortholog; an integral membrane protein required for mating; role in thigmotropism; transcript is opaque-specific and a-specific; activated by Cph1 or alpha pheromone || 1 -0.45 -0.37 0.91 1.33 -0.23 0.26 -0.40 -0.06 0.42 -0.64 -0.45 -0.81 0.04 -0.57 -0.36 -0.10
7676 || orf19.4251 || ZCF22 || || Predicted Zn(II)2Cys6 transcription factor || 1 -0.30 -0.08 1.23 1.46 0.30 0.74 -0.18 0.08 0.79 -0.89 -0.18 -0.48 -0.04 -0.76 -0.28 -0.80
7677 || orf19.1728 || || || Ortholog of C. dubliniensis CD36 : Cd36_81190, C. parapsilosis CDC317 : CPAR2_503840, Debaryomyces hansenii CBS767 : DEHA2A09042g and Pichia stipitis Pignal : PICST_42519 || 1 -0.22 -0.22 0.73 1.41 0.10 0.56 -0.21 -0.12 0.72 -0.81 0.01 -0.10 0.28 -0.45 -0.16 -0.29
7678 || orf19.3418 || || || Ortholog(s) have endoplasmic reticulum, fungal-type vacuole localization || 1 0.15 0.03 1.25 1.61 -0.03 0.80 0.30 -0.50 0.39 -0.82 0.19 -0.20 0.13 -0.46 0.50 0.22
7679 || orf19.6992 || || || Predicted MFS membrane transporter, member of the drug:proton antiporter (12 spanner) (DHA1) family; Spider biofilm induced || 1 0.13 0.31 1.55 1.09 0.44 0.52 0.58 -0.49 0.69 -0.54 0.40 0.00 0.31 -0.15 0.29 -0.01
7680 || orf19.3517 || || || Ortholog(s) have Dsc E3 ubiquitin ligase complex, endoplasmic reticulum, fungal-type vacuole lumen localization || 1 0.17 0.28 1.18 0.50 0.38 0.43 -0.12 -0.25 0.03 -0.39 -0.06 -0.15 0.34 -0.44 0.09 -0.11
7681 || orf19.3655 || || || Ortholog of C. dubliniensis CD36 : Cd36_60640, C. parapsilosis CDC317 : CPAR2_602930, Candida tenuis NRRL Y-1498 : CANTEDRAFT_115038 and Pichia stipitis Pignal : PICST_31932 || 1 0.56 0.61 1.15 0.56 0.31 0.51 -0.09 -0.08 0.16 -0.45 -0.34 -0.38 0.41 -0.90 -0.02 0.10
7682 || orf19.2074 || || || Ortholog of Candida albicans WO-1 : CAWG_03833 || 1 1.00 0.05 1.25 1.13 -0.23 0.72 -0.05 0.04 0.08 -0.68 -0.85 -0.69 0.25 -0.81 -0.48 -0.96
7683 || orf19.3738 || PGA22 || || Putative GPI-anchored protein; adhesin-like protein || 1 0.31 -0.08 0.97 1.10 -0.08 0.41 0.24 0.28 0.16 -0.53 0.10 -0.16 -0.06 -0.65 -0.08 -0.49
7684 || orf19.727 || || || Predicted ORF overlapping the Major Repeat Sequence on chromosome R; member of a family encoded by FGR6-related genes in the RB2 repeat sequence || 1 0.25 -0.11 0.96 1.41 -0.33 0.43 0.08 -0.03 0.50 -0.46 -0.16 -0.53 -0.05 -0.37 0.22 -0.63
7685 || orf19.1776 || || || Putative pantetheine-phosphate adenylyltransferase (PPAT); which catalyzes 4th step in coenzyme A biosynthesis from pantothenate; rat catheter biofilm repressed || 1 0.40 0.12 1.13 1.20 -0.21 0.70 0.08 0.15 0.61 -0.24 0.01 0.14 -0.12 -0.22 -0.26 -0.23
7686 || orf19.3693 || PGA5 || || Putative GPI-anchored beta-1,3-glucanosyltransferase with similarity to the A. fumigatus GEL family; fungal-specific (no human or murine homolog) || 1 1.14 0.25 1.79 1.71 -0.28 1.22 0.13 0.06 1.21 -0.38 0.15 -0.41 -0.01 -0.52 -0.15 -0.74
7687 || orf19.4804 || LIP2 || || Secreted lipase; member of a differentially expressed lipase gene family; expressed in alimentary tract, but not oral tissue, during mouse oral infection; may have a role in nutrition and/or in creating an acidic microenvironment || 1 0.92 0.15 1.37 1.68 -0.35 0.77 0.08 -0.02 0.81 0.04 0.12 -0.44 -0.28 -0.57 -0.22 -0.45
7688 || orf19.7014 || || || Putative protein of unknown function; transcription is positively regulated by Tbf1p; overlaps orf19.7015 || 1 0.87 -0.19 1.32 1.24 0.12 0.81 -0.06 0.05 0.74 -0.30 -0.35 -0.13 -0.21 -0.76 -0.03 -0.33
7689 || orf19.7419 || HNT2 || || Putative dinucleoside triphosphate hydrolase; induced upon low-level peroxide stress || 1 1.03 0.11 1.55 1.52 -0.15 1.03 0.05 -0.06 1.13 -0.41 -0.72 -0.24 0.01 -0.77 0.09 -0.62
7690 || orf19.5763 || || || Has domain(s) with predicted oxidoreductase activity and role in metabolic process || 1 1.01 0.27 1.51 1.38 0.08 1.15 0.08 0.20 0.71 -0.51 -0.50 -0.63 0.05 -0.66 0.15 -0.75
7691 || orf19.5837 || || || Ortholog(s) have 4-amino-4-deoxychorismate lyase activity, role in folic acid biosynthetic process and cytoplasm localization || 1 0.95 0.24 1.26 1.06 0.02 0.78 0.44 0.27 0.65 -0.54 -0.50 -0.47 0.12 -0.69 -0.00 -0.74
7692 || orf19.2897 || SOU2 || || Protein similar to Sou1; not required for utilization of L-sorbose; Spider biofilm induced || 1 1.04 0.28 1.33 1.05 0.05 0.78 -0.11 -0.10 0.87 -0.33 -0.76 -0.22 0.03 -0.43 -0.09 -0.86
7693 || orf19.4293 || || || Ortholog(s) have role in iron-sulfur cluster assembly, ribosomal large subunit export from nucleus, tRNA wobble uridine modification and cytosol, nucleus localization || 1 0.95 -0.09 0.94 0.78 -0.30 0.49 0.08 0.15 0.55 -0.44 -0.36 -0.43 0.15 -0.72 0.09 -0.75
7694 || orf19.6629 || ISC1 || || Mitochondrial membrane localized inositol phosphosphingolipid phospholipase C; hydrolyzes complex sphingolipids to produce ceramide; mutant is viable || 1 0.80 -0.05 1.20 0.99 0.01 1.09 0.31 0.30 0.70 -0.36 0.04 -0.69 -0.00 -0.55 -0.23 -0.76
7695 || orf19.3903 || MRV3 || || Ortholog of Candida albicans WO-1 : CAWG_04793 || 1 0.74 -0.20 1.68 1.61 -0.47 0.62 0.05 0.11 1.02 -0.60 -0.14 -0.92 -0.25 -0.85 -0.57 -0.91
7696 || orf19.4085 || || || Protein of unknown function; transcript detected on high-resolution tiling arrays || 1 -0.04 0.12 1.89 1.87 0.10 1.03 -0.23 0.05 0.59 -0.70 -0.95 -0.86 -0.29 -1.14 -0.47 -1.28
7697 || orf19.690 || PLB2 || || Putative phospholipase B; conserved catalytic region; 6 putative N-glycosylation motifs; predicted secretion signal; no GPI anchor predicted; fungal-specific (no human or murine homolog) || 1 0.29 0.40 1.92 1.68 0.36 0.69 -0.08 0.19 0.42 -0.79 -0.81 -0.66 0.09 -0.76 -0.32 -1.02
7698 || orf19.2168 || || || Putative sterol deacetylase; flow model biofilm induced; rat catheter biofilm repressed || 1 0.53 0.34 1.44 1.08 0.34 0.29 0.06 0.12 0.70 -0.26 -0.26 -0.38 0.23 -0.34 -0.33 -0.75
7699 || orf19.1325 || ECM38 || || Putative gamma-glutamyltransferase; alkaline upregulated; Spider biofilm induced; possibly an essential gene, disruptants not obtained by UAU1 method || 1 0.31 0.21 1.58 1.76 0.07 0.59 0.12 -0.00 0.92 -0.34 -0.06 -0.66 0.21 -0.39 -0.15 -1.14
7700 || orf19.5121 || OPT5 || || Oligopeptide transporter; fungal-specific (no human or murine homolog); induced by BSA, but not by tetrapeptide or pentapeptide || 1 0.08 0.30 1.32 1.28 0.11 0.34 -0.09 -0.16 0.90 -0.18 -0.30 -0.40 0.49 -0.41 -0.19 -0.72
7701 || orf19.1584 || || || Predicted MFS membrane transporter; monocarboxylate porter family member; colony morphology-related gene regulation by Ssn6; flow model biofilm induced; Spider biofilm induced || 1 0.30 0.44 1.38 1.76 0.15 0.94 0.03 0.17 0.95 -0.64 -0.54 -0.79 0.18 -0.46 0.00 -0.79
7702 || orf19.6008.3 || || || Ortholog of C. dubliniensis CD36 : Cd36_00920, Debaryomyces hansenii CBS767 : DEHA2F20724g, Pichia stipitis Pignal : PICST_32745 and Candida albicans WO-1 : CAWG_01277 || 1 0.33 0.60 1.56 1.41 -0.10 0.45 0.25 0.56 0.73 -0.63 -0.38 -0.45 0.55 -0.31 -0.20 -0.68
7703 || orf19.1133 || MSB1 || || Putative regulator of transcription; expression in S. cerevisiae flo8 and flo11 mutants suggests a role in regulation of adhesion factors || 1 0.39 0.31 0.96 1.08 -0.02 0.22 0.02 0.15 0.34 -0.31 -0.45 -0.46 0.29 -0.14 -0.20 -0.35
7704 || orf19.5250 || || || Has domain(s) with predicted cofactor binding activity || 1 0.47 0.65 1.22 1.38 0.02 0.36 -0.08 0.16 0.32 -0.29 -0.71 -0.46 0.20 -0.35 -0.11 -0.53
7705 || orf19.4175 || TOK1 || || Outwardly rectifying, noisily gated potassium channel; modulates sensitivity to human salivary histatin (Hst5); very similar to S. cerevisiae Tok1p; Bcr1-repressed in RPMI a/a biofilms || 1 0.35 0.42 1.69 1.70 0.23 0.60 0.24 -0.50 0.75 -0.76 -0.57 -0.29 0.33 -0.29 0.19 -0.65
7706 || orf19.3432 || || || Predicted membrane transporter, member of the drug:proton antiporter (12 spanner) (DHA1) family, major facilitator superfamily (MFS); induced by nitric oxide || 1 0.43 0.36 0.95 1.03 0.39 0.37 -0.02 -0.02 0.25 -0.57 -0.15 -0.30 0.17 -0.46 -0.22 -0.48
7707 || orf19.5426 || || || Putative patatin-like phospholipase; macrophage-regulated gene; fungal-specific (no human or murine homolog) || 1 0.45 0.40 1.12 1.54 0.28 0.54 0.34 0.55 0.55 -0.52 -0.02 -0.43 0.23 -0.30 0.25 -0.75
7708 || orf19.5191 || FGR6-1 || || Protein lacking an ortholog in S. cerevisiae; member of a family encoded by FGR6-related genes in the RB2 repeat sequence; transposon mutation affects filamentous growth || 1 0.30 0.31 1.31 1.57 0.24 0.60 0.06 0.38 0.51 -0.56 -0.09 -0.64 0.49 -0.53 0.21 -0.23
7709 || orf19.1728 || || || Ortholog of C. dubliniensis CD36 : Cd36_81190, C. parapsilosis CDC317 : CPAR2_503840, Debaryomyces hansenii CBS767 : DEHA2A09042g and Pichia stipitis Pignal : PICST_42519 || 1 0.19 0.25 0.92 1.70 0.13 0.44 0.25 0.34 0.29 -0.37 -0.24 -0.43 0.28 -0.33 0.12 -0.02
7710 || orf19.1547 || || || Ortholog(s) have double-stranded DNA binding, polynucleotide 3'-phosphatase activity and role in double-strand break repair || 1 0.07 0.09 0.59 0.85 0.14 0.18 0.07 0.31 0.16 -0.21 -0.27 -0.25 0.29 -0.11 0.12 -0.17
7711 || orf19.3539 || || || Predicted nucleolar S-adenosylmethionine-dependent rRNA methyltransferase; Spider biofilm induced || 1 0.34 0.27 0.95 0.92 0.13 0.60 -0.07 0.08 0.12 -0.13 -0.33 -0.08 0.09 -0.56 0.17 -0.12
7712 || orf19.5037 || HRQ2 || || Protein of unknown function; mutants are viable; rat catheter and Spider biofilm induced || 1 0.32 0.34 0.98 0.67 0.10 0.48 -0.12 0.01 0.24 -0.28 -0.38 -0.04 0.03 -0.73 -0.08 -0.21
7713 || orf19.4114 || FAA2-1 || || Predicted long chain fatty acid CoA ligase; upregulated upon phagocytosis; induced by nitric oxide independent of Yhb1 || 1 0.42 0.41 1.17 0.82 0.13 0.43 0.12 0.17 0.36 -0.24 -0.23 -0.38 0.05 -0.66 0.04 -0.09
7714 || orf19.329 || || || Putative pre-mRNA branch point binding protein; role in mRNA splicing via spliceosome; Spider biofilm repressed || 1 0.19 0.15 0.64 0.61 0.22 0.45 -0.06 0.07 -0.06 0.01 -0.18 -0.14 0.04 -0.23 0.09 -0.42
7715 || orf19.5457 || || || Ortholog(s) have Golgi apparatus, endoplasmic reticulum localization || 1 0.22 0.30 0.73 0.50 0.29 0.56 -0.03 -0.10 0.14 0.05 -0.54 -0.07 0.05 -0.28 0.17 -0.23
7716 || orf19.3906 || MRV6 || || Ortholog of Candida albicans WO-1 : CAWG_04796 || 1 0.30 0.12 1.19 0.61 0.50 0.40 -0.01 0.02 -0.02 -0.08 -0.62 -0.03 0.28 -0.39 0.07 -0.19
7717 || orf19.4543 || UGA2 || || Predicted succinate semialdehyde dehydrogenase; predicted role in glutamate catabolism; transcription regulated by Mig1, Tup1, Gcn4; mutants are viable || 1 0.32 0.22 1.42 0.87 0.93 1.49 -0.28 -0.32 0.48 -0.41 -0.52 -0.09 0.11 -0.66 0.88 0.43
7718 || orf19.1826 || MDM34 || || Putative zinc finger transcription factor; macrophage-downregulated; flow model biofilm induced; flow model and Spider biofilm induced || 1 0.38 0.12 1.30 1.32 0.65 1.21 -0.14 -0.49 0.87 -0.15 -0.57 -0.19 0.29 -0.49 0.65 -0.33
7719 || orf19.5683 || || || Putative integral membrane protein of unknown function; clade-associated gene expression; Spider biofilm induced || 1 0.59 0.72 2.00 1.51 1.09 1.53 0.38 -0.43 0.74 -0.63 -0.45 -0.15 0.65 -0.23 0.79 -0.39
7720 || orf19.5727 || || || Ortholog of C. dubliniensis CD36 : Cd36_64130, C. parapsilosis CDC317 : CPAR2_601230, Candida tenuis NRRL Y-1498 : CANTEDRAFT_115908 and Debaryomyces hansenii CBS767 : DEHA2E12540g || 1 0.43 0.27 1.65 1.49 0.80 1.19 0.07 -0.38 0.08 -0.50 0.06 -0.06 0.38 -0.25 0.69 0.31
7721 || orf19.459 || ADP1 || || Putative PDR-subfamily ABC transporter; similar to WHITE subfamily proteins; gene used for strain identification by multilocus sequence typing || 1 0.41 0.19 1.33 1.34 0.43 0.84 0.45 0.14 0.30 -0.56 -0.50 -0.04 0.12 -0.50 0.59 0.06
7722 || orf19.7148 || TPO2 || || Putative polyamine transport protein; fungal-specific (no human or murine homolog) || 1 0.43 0.28 1.16 1.08 0.43 0.74 0.12 0.26 0.17 -0.45 -0.18 0.04 -0.07 -0.39 0.58 0.38
7723 || orf19.4044 || MUM2 || || Protein similar to S. cerevisiae Mum2, a protein essential for meiotic DNA replication and sporulation; induced by alpha pheromone in SpiderM medium; transcript regulated by Tup1 || 1 0.56 0.55 1.77 1.38 0.70 1.05 0.25 -0.09 0.18 -0.54 0.22 0.31 0.06 -1.01 0.43 0.42
7724 || orf19.201 || || || Protein of unknown function; unmerged from orf19.202 in a revision of Assembly 21 || 1 0.59 0.38 0.88 1.07 0.59 0.88 0.07 -0.05 0.12 -0.41 -0.20 0.17 0.18 -0.67 0.15 0.17
7725 || orf19.4626 || || || Ortholog(s) have role in TOR signaling cascade, positive regulation of transcription from RNA polymerase I promoter and cytosol, extrinsic to membrane, nucleus localization || 1 0.28 -0.03 1.21 1.14 0.61 0.70 -0.16 -0.06 0.51 -0.17 -0.35 -0.01 -0.12 -0.49 0.09 0.20
7726 || orf19.3906 || MRV6 || || Ortholog of Candida albicans WO-1 : CAWG_04796 || 1 0.11 0.13 1.53 1.90 0.32 0.94 0.02 0.29 0.36 -0.56 -0.46 0.09 -0.29 -0.98 -0.23 0.03
7727 || orf19.1643 || || || Ortholog(s) have serine-type endopeptidase activity, role in regulation of mitochondrion organization, signal peptide processing and mitochondrial inner membrane localization || 1 0.18 -0.09 1.08 1.27 0.16 0.88 0.00 0.11 0.11 -0.63 -0.33 -0.05 -0.12 -0.83 0.25 0.00
7728 || orf19.207 || PGA55 || || GPI-anchored adhesin-like protein; filament induced; regulated by Nrg1, Tup1; regulated upon hyphal formation; mRNA binds to She3 and is localized to yeast-form buds and hyphal tips; induced during chlamydospore formation || 1 0.28 0.06 1.03 1.43 0.35 0.80 0.55 0.22 0.46 -0.77 -0.36 -0.48 0.29 -0.38 0.24 0.26
7729 || orf19.2350 || || || Protein similar to S. cerevisiae Yor378w; MFS family transporter; transposon mutation affects filamentous growth; null mutants are viable; fungal-specific (no human or murine homolog) || 1 0.57 0.35 1.97 1.87 0.36 1.10 0.85 0.71 0.78 -0.58 -0.04 -0.44 0.50 -0.49 0.31 0.43
7730 || orf19.2393 || || || Putative transcription factor with zinc finger DNA-binding motif || 1 0.53 0.27 1.73 1.59 1.12 1.64 0.51 0.27 0.56 -0.46 0.39 -0.18 0.34 -0.39 0.04 -0.45
7731 || orf19.6350 || || || Ortholog of C. dubliniensis CD36 : Cd36_11890 and Candida albicans WO-1 : CAWG_00170 || 1 0.26 0.48 1.20 1.48 0.65 1.23 -0.14 -0.40 -0.20 -0.53 -0.37 -0.30 0.15 -0.38 0.17 -0.50
7732 || orf19.1641 || || || Ortholog(s) have cytosol, extracellular region, nucleus localization || 1 -0.02 0.35 1.02 1.11 0.70 1.55 -0.38 -0.31 0.07 -0.60 -0.61 -0.58 0.05 -0.28 0.08 -0.21
7733 || orf19.896 || CHK1 || || Histidine kinase; 2-component signaling, cell wall synthesis; hyphal growth defect; avirulent in mouse, not rat vaginal infection; phagocytosis rate increased; Spider biofilm induced; required for RPMI biofilm; Bcr1-induced in a/a biofilm || 1 0.13 0.22 1.29 1.49 0.56 1.23 -0.22 0.04 0.35 -0.57 -0.65 -0.59 0.29 -0.10 0.07 -0.58
7734 || orf19.7209 || || || Putative Rho GDP dissociation inhibitor; induced by nitric oxide independent of Yhb1p || 1 0.07 0.03 1.39 1.38 0.47 0.98 0.01 -0.28 0.25 -0.05 -0.05 -0.59 -0.23 -0.34 -0.14 -0.55
7735 || orf19.4803 || || || Ortholog of Candida albicans WO-1 : CAWG_00488 || 1 -0.19 -0.16 1.47 1.59 0.49 1.08 -0.04 -0.28 0.58 0.05 -0.17 -0.38 -0.01 -0.28 -0.10 -0.04
7736 || orf19.1641 || || || Ortholog(s) have cytosol, extracellular region, nucleus localization || 1 0.15 -0.05 1.51 1.18 0.60 1.45 -0.30 0.05 0.06 -0.57 -0.26 -0.19 -0.26 0.06 0.12 0.28
7737 || orf19.5649 || || || Ortholog of Candida lusitaniae ATCC 42720 : CLUG_00275 and Candida albicans WO-1 : CAWG_03759 || 1 0.04 0.59 1.45 0.81 0.08 0.54 0.02 -0.10 0.37 -0.24 0.07 0.01 0.08 -0.30 -0.12 -0.55
7738 || orf19.7320 || LIP7 || || Probable lipase, part of a gene family whose members are differentially expressed during infection; lacks a signal sequence for secretion, unlike other family members; may have a role in nutrition or in creating an acidic microenvironment || 1 -0.10 0.23 1.15 0.75 0.20 0.41 0.12 -0.07 0.53 -0.11 -0.12 0.03 0.40 -0.26 -0.02 -0.53
7739 || orf19.644 || HGT9 || || Putative glucose transporter of the major facilitator superfamily; the C. albicans glucose transporter family comprises 20 members; 12 probable membrane-spanning segments; induced at low (0.2%, compared to 2%) glucose in rich media; intron || 1 0.31 0.33 0.95 1.05 0.18 0.29 -0.06 -0.04 0.05 -0.33 0.19 0.12 0.18 -0.28 -0.22 -0.52
7740 || orf19.4122 || || || Ortholog(s) have acyl-CoA hydrolase activity, role in fatty acid beta-oxidation and mitochondrion, peroxisome localization || 1 0.41 0.33 1.15 1.79 0.04 0.85 -0.30 -0.18 -0.05 -0.16 0.04 0.31 -0.26 -0.38 -0.49 -0.36
7741 || orf19.5975 || TRY4 || || C2H2 transcription factor; fluconazole-repressed; induced in ssr1 mutant; required for yeast cell adherence to silicone substrate; Spider biofilm induced || 1 0.87 0.25 2.10 2.87 -0.02 1.10 -0.02 -0.24 0.50 -0.30 -0.21 0.20 0.56 0.38 -0.46 -0.41
7742 || orf19.7111 || || || Putative mitochondrial outer membrane protein membrane fission effector; possibly an essential gene, disruptants not obtained by UAU1 method || 1 0.28 0.21 0.71 1.15 0.13 -0.01 -0.18 0.10 0.26 -0.10 -0.30 -0.11 0.41 -0.53 -0.06 -0.40
7743 || orf19.7372 || MRR1 || || Putative Zn(II)2Cys6 transcription factor; regulator of MDR1 transcription; gain-of-function mutations cause upregulation of MDR1 (a plasma membrane multidrug efflux pump) and multidrug resistance; Hap43-induced || 1 0.66 0.07 0.99 0.97 0.08 0.53 -0.34 -0.35 0.28 0.09 -0.14 -0.03 -0.25 -0.16 0.05 -0.33
7744 || orf19.1516 || || || Ortholog(s) have ubiquitin-specific protease activity || 1 0.15 0.16 0.44 0.64 -0.13 0.01 -0.14 -0.05 0.14 -0.09 -0.26 0.15 -0.14 -0.13 -0.34 0.03
7745 || orf19.6896 || || || Predicted ORF overlapping the Major Repeat Sequence on chromosome 7; member of a family encoded by FGR6-related genes in the RB2 repeat sequence || 1 0.27 0.14 0.76 0.61 0.08 -0.11 -0.29 -0.16 0.23 -0.07 -0.47 0.03 0.17 -0.29 -0.27 0.15
7746 || orf19.1096 || || || Has domain(s) with predicted voltage-gated chloride channel activity, role in chloride transport, transmembrane transport and membrane localization || 1 0.19 0.01 0.74 0.75 -0.14 -0.33 -0.09 0.40 0.06 -0.03 -0.38 -0.00 0.05 -0.19 -0.00 -0.02
7747 || orf19.7379 || FAA2 || || Putative acyl CoA synthetase; expression regulated upon white-opaque switch; rat catheter biofilm induced; Spider biofilm induced || 1 -0.00 0.12 1.16 1.14 -0.33 -0.24 0.17 0.31 0.29 -0.06 -0.64 -0.03 0.07 -0.12 0.01 0.04
7748 || orf19.6911 || || || Ortholog of Candida albicans WO-1 : CAWG_05482 || 1 0.15 0.12 1.53 1.69 -0.14 0.33 0.23 0.30 0.14 -0.29 -0.55 -0.33 0.01 -0.56 -0.25 0.18
7749 || orf19.3443 || OYE2 || || Putative NAPDH dehydrogenase; induced by nitric oxide; Spider biofilm induced || 1 0.48 0.48 1.00 1.16 -0.38 0.28 0.56 0.31 0.35 -0.21 -0.60 -0.13 -0.01 -0.46 -0.30 -0.30
7750 || orf19.2783 || PIR32 || || Cell wall protein, putative structural component of the cell wall; mutation leads to increased chitin content, increased virulence and resistance to stresses; macrophage-induced gene || 1 -0.10 0.47 1.04 0.70 -0.33 0.19 -0.08 0.06 0.44 -0.33 -0.20 0.07 0.21 -0.21 -0.33 0.23
7751 || orf19.3544 || || || Putative protein of unknown function; Hap43p-repressed gene || 1 -0.04 0.17 1.59 1.20 -0.75 0.17 -0.14 -0.29 0.54 -0.67 -0.61 -0.29 0.30 -0.17 -0.01 0.11
7752 || orf19.2176 || IFM3 || || Protein with a 2-hydroxyacid dehydrogenase catalytic domain; Hap43-repressed; Plc1-regulated; overlaps orf19.2177 || 1 0.11 0.04 0.89 0.59 -0.76 0.00 0.06 0.01 0.60 -0.16 -0.34 -0.25 0.13 0.17 -0.12 0.14
7753 || orf19.6606 || || || Ortholog of C. parapsilosis CDC317 : CPAR2_201040, Candida tenuis NRRL Y-1498 : CANTEDRAFT_112677, Debaryomyces hansenii CBS767 : DEHA2E02420g and Pichia stipitis Pignal : PICST_37559 || 1 -0.06 0.19 0.99 0.70 -0.06 0.11 0.11 0.19 0.33 0.00 -0.05 -0.08 0.17 0.26 0.04 -0.38
7754 || orf19.4418 || FMT1 || || Putative methionyl-tRNA transformylase; induced upon adherence to polystyrene || 1 -0.09 0.23 0.90 0.83 0.15 -0.22 0.21 0.20 0.01 0.15 -0.22 0.25 0.08 0.11 0.05 -0.22
7755 || orf19.1249 || || || Ortholog(s) have 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino]imidazole-4-carboxamide isomerase activity, role in histidine biosynthetic process and cytosol, nucleus localization || 1 0.25 0.30 1.41 1.01 0.00 0.01 0.14 -0.11 0.30 0.10 -0.22 -0.04 0.18 0.17 0.09 -0.01
7756 || orf19.1661 || DBP5 || || Ortholog(s) have RNA helicase activity, RNA-dependent ATPase activity, inositol hexakisphosphate binding activity and role in mRNA export from nucleus, translational termination || 1 0.21 0.31 1.14 1.08 0.07 -0.34 0.47 0.01 0.36 0.04 -0.07 -0.11 0.25 0.31 -0.04 0.11
7757 || orf19.5820 || UGA6 || || Putative GABA-specific permease; decreased transcription is observed upon benomyl treatment or in an azole-resistant strain that overexpresses MDR1 || 1 0.20 0.58 1.44 1.43 0.07 -0.31 0.46 0.08 0.40 -0.05 0.04 0.03 0.25 0.03 0.39 0.42
7758 || orf19.5498 || EFH1 || || APSES transcription factor; homodimer; minor role in transcriptional regulation vs Efg1; regulates filamentous growth, phenotypic switch; EFG1 and EFH1 genetically interact; expression interferes with mouse intestinal tract colonization || 1 0.12 0.31 0.98 0.85 0.13 -0.12 -0.12 -0.01 0.17 -0.19 0.13 0.26 0.19 -0.20 -0.05 0.27
7759 || orf19.1438 || || || Protein with homology to NADH dehydrogenase; regulated by Sef1p-, Sfu1p-, and Hap43p || 1 0.17 0.09 1.45 1.11 0.05 0.34 -0.07 -0.03 0.77 0.12 -0.17 0.03 0.22 -0.23 -0.16 0.15
7760 || orf19.442 || || || Ortholog of Candida guilliermondii ATCC 6260 : PGUG_05525, Candida lusitaniae ATCC 42720 : CLUG_03378 and Candida albicans WO-1 : CAWG_00876 || 1 -0.05 0.17 4.14 2.05 0.19 0.41 -0.50 -0.44 0.21 0.40 0.33 0.02
7761 || orf19.2237 || SPR1 || || Putative GPI-anchored protein; similar but not orthologous to S. cerevisiae Spr1, a sporulation-specific exo-1,3-beta-glucanase; mutant is viable || 1 -0.16 0.25 1.34 0.87 -0.13 0.07 -0.10 -0.09 0.46 -0.22 -0.20 -0.21 -0.16 -0.10 -0.07 0.32
7762 || orf19.7208 || CSK1 || || Putative mitogen-activated protein (MAP) kinase with an unknown role; null mutant produces wrinkled colonies; similar to S. cerevisiae Smk1p, which is a protein kinase required for sporulation || 1 -0.07 -0.08 1.73 1.39 0.10 0.12 -0.12 -0.02 0.41 -0.09 -0.15 0.38 -0.33 0.37 -0.04 0.17
7763 || orf19.5424 || || || Ortholog of Candida albicans WO-1 : CAWG_02376 || 1 0.53 0.40 4.60 1.65 -0.08 0.77 -0.59 0.23 -0.29 -0.48 -0.61 0.34 -0.49 -0.07 0.70 0.69
7764 || orf19.5432 || TPT1 || || tRNA 2'-phosphotransferase; enzyme of tRNA splicing; functionally complements viability of S. cerevisiae tpt1 null mutant || 1 0.12 0.17 1.28 1.36 0.03 0.57 0.10 0.18 -0.03 -0.66 -0.11 0.38 0.49 -0.16 0.25 0.25
7765 || orf19.690 || PLB2 || || Putative phospholipase B; conserved catalytic region; 6 putative N-glycosylation motifs; predicted secretion signal; no GPI anchor predicted; fungal-specific (no human or murine homolog) || 1 0.01 1.17 1.49 1.39 -0.34 0.66 -0.03 0.16 0.52 -0.10 -0.02 -0.52 0.28 -0.11 -0.15 -0.29
7766 || orf19.3760 || DLH1 || || Functional homolog of S. cerevisiae Dmc1; a meiosis-specific protein required for repair of double-strand breaks and pairing between homologous chromosomes || 1 0.56 1.42 1.46 1.38 -0.48 0.66 -0.14 -0.02 0.54 0.14 -0.55 0.06 0.10 0.00 -0.39 -0.03
7767 || orf19.5293 || || || Ortholog of C. dubliniensis CD36 : Cd36_43710, C. parapsilosis CDC317 : CPAR2_402940, Candida tenuis NRRL Y-1498 : CANTEDRAFT_114940 and Debaryomyces hansenii CBS767 : DEHA2C09196g || 1 0.34 0.58 1.11 1.00 -0.25 0.02 0.25 0.41 0.29 -0.17 0.22 -0.16 0.25 -0.63 -0.01 0.24
7768 || orf19.4803 || || || Ortholog of Candida albicans WO-1 : CAWG_00488 || 1 0.55 0.16 1.36 1.48 0.95 0.41 -0.28 -0.27 1.53 -0.04 0.08 1.07 0.37 -0.56 -0.76
7769 || orf19.7381 || AHR1 || || Zn(II)2Cys6 transcription factor; involved in regulation of adhesion genes; involved in white-opaque switch; forms complex with Mcm1; mutant is sensetive to 5-fluorocytosine and lithium chloride; Spider biofilm induced || 1 0.26 0.48 0.91 0.70 0.38 0.09 -0.20 -0.30 0.78 -0.41 0.12 0.66 0.77 0.16 -0.13 -0.46
7770 || orf19.2671 || || || Protein with a predicted FAD-dependent pyridine nucleotide reductase domains; putative oxidoreductase; Plc1-regulated; possibly an essential gene, disruptants not obtained by UAU1 method || 1 0.16 0.35 0.68 0.73 0.46 0.19 -0.32 -0.29 0.61 -0.60 -0.10 0.22 0.69 0.31 -0.05 0.01
7771 || orf19.7579 || FGR34 || || Protein lacking an ortholog in S. cerevisiae; transposon mutation affects filamentous growth || 1 -0.20 0.23 0.53 0.38 0.14 0.02 -0.20 -0.34 0.60 -0.19 -0.44 -0.06 0.34 0.02 -0.33 -0.16
7772 || orf19.5191 || FGR6-1 || || Protein lacking an ortholog in S. cerevisiae; member of a family encoded by FGR6-related genes in the RB2 repeat sequence; transposon mutation affects filamentous growth || 1 0.10 0.21 0.67 0.43 0.16 0.11 -0.27 -0.08 0.23 -0.05 -0.31 -0.15 0.39 -0.03 -0.28 -0.09
7773 || orf19.3490 || FGR6-4 || || Protein lacking an ortholog in S. cerevisiae; member of a family encoded by FGR6-related genes in the RB2 repeat sequence; transposon mutation affects filamentous growth || 1 0.14 0.16 0.75 0.41 0.14 0.14 -0.63 -0.18 0.48 -0.10 -0.33 -0.37 0.28 0.07 -0.10 -0.18
7774 || orf19.1746 || || || Protein similar to S. cerevisiae meiosis-specific, spore-wall-localized protein Ssp2p, which is required for wild-type outer spore wall formation in S. cerevisiae; possibly an essential gene (UAU1 method); Hap43p-repressed || 1 0.10 0.13 1.30 0.42 0.02 0.50 -0.56 -0.49 1.01 -0.29 -0.51 -0.27 0.19 -0.18 -0.60 -0.05
7775 || orf19.6922 || || || Dubious open reading frame || 1 -0.02 0.26 1.56 0.63 0.36 0.80 -0.22 -0.37 1.09 -0.30 -0.62 -0.22 0.29 -0.48 -0.60 -0.27
7776 || orf19.2878 || PGA15 || || Putative GPI-anchored protein || 1 0.29 0.60 1.14 0.54 0.41 1.23 -0.73 -0.19 1.13 -0.36 -0.37 -0.11 0.43 -0.08 -0.59 -0.41
7777 || orf19.647.3 || || || Protein of unknown function; Spider biofilm induced || 1 0.22 0.38 1.34 0.65 0.39 0.57 -0.32 -0.10 1.23 -0.16 -0.58 -0.31 0.86 -0.66 0.00 -0.78
7778 || orf19.2731 || || || Ortholog of Debaryomyces hansenii CBS767 : DEHA2E16016g, Pichia stipitis Pignal : PICST_38487, Spathaspora passalidarum NRRL Y-27907 : SPAPADRAFT_58603 and Candida tropicalis MYA-3404 : CTRG_00248 || 1 -0.07 0.41 0.72 0.32 0.81 0.47 -0.29 -0.33 1.00 -0.25 -0.58 -0.39 0.72 -0.16 -0.42 -0.16
7779 || orf19.3018 || SPP1 || || Putative histone methyltransferase; induced by nitric oxide independent of Yhb1p; cell-cycle regulated periodic mRNA expression || 1 0.01 0.33 1.26 -0.04 0.29 0.44 -0.19 -0.19 0.70 0.06 -0.41 0.03 0.47 -0.07 -0.03 -0.32
7780 || orf19.3178 || || || Ortholog(s) have RNA binding activity, role in mRNA splicing, via spliceosome and U2-type prespliceosome localization || 1 -0.14 0.17 1.00 0.28 0.37 0.56 -0.19 -0.25 0.68 0.19 -0.43 -0.06 0.22 0.08 -0.16 0.07
7781 || orf19.2174 || RAD57 || || Putative DNA recombination and repair protein; induced by interaction with macrophage; transcript is regulated by Nrg1, Mig1, and Tup1; essential protein; S. cerevisiae ortholog is essential || 1 -0.01 0.37 0.76 0.74 0.31 0.68 -0.39 -0.31 1.30 0.38 -0.49 0.21 0.46 -0.05 -0.67 0.06
7782 || orf19.420 || || || Protein of unknown function || 1 0.07 0.57 1.53 1.24 0.59 1.02 -0.46 -0.48 1.48 0.15 -0.84 0.45 0.82 0.11 -0.41 0.13
7783 || orf19.5748 || || || Ortholog of C. dubliniensis CD36 : Cd36_64250, Candida tenuis NRRL Y-1498 : cten_CGOB_00218, Debaryomyces hansenii CBS767 : DEHA2E19888g and Spathaspora passalidarum NRRL Y-27907 : spas_CGOB_00025 || 1 -0.10 0.27 0.88 0.71 0.19 0.61 -0.16 0.04 1.29 0.18 -0.06 0.12 0.51 0.31 -0.14 0.30
7784 || orf19.5342.1 || MTR2 || || Nuclear export protein; member of NTF2 family; monomeric in solution; interacts with Mex67p via the NTF2-like domain || 1 0.19 0.41 1.01 0.44 0.25 0.29 -0.09 0.00 1.18 0.42 -0.11 -0.05 0.69 0.25 -0.34 0.09
7785 || orf19.6588 || NBP2 || || Protein containing an SH3 domain; involved in vacuolar fusion in hyphae; mutants form multiple germ tubes; Spider biofilm induced || 1 0.08 0.21 0.76 0.37 0.25 0.76 0.14 -0.02 0.88 0.40 -0.23 0.36 0.53 0.61 -0.27 0.32
7786 || orf19.1881 || || || Putative broad-specificity lysophospholipid acyltransferase; role in glycerophospholipid biosynthesis; rat catheter biofilm repressed || 1 0.03 0.13 0.60 0.34 -0.04 0.13 -0.05 -0.12 0.20 -0.02 -0.22 0.12 0.43 0.12 -0.24 0.22
7787 || orf19.5586 || || || Ortholog(s) have phosphatidylinositol-3,5-bisphosphate 5-phosphatase activity, role in phosphatidylinositol dephosphorylation and PAS complex, cytosol, extrinsic to membrane, fungal-type vacuole membrane localization || 1 0.32 0.71 0.69 0.83 0.12 0.33 -0.10 -0.05 0.65 -0.17 -0.31 0.39 0.39 -0.12 -0.17 -0.04
7788 || orf19.1794 || || || Ortholog(s) have RNA binding, translation regulator activity and role in Group I intron splicing, mitochondrial respiratory chain complex IV biogenesis, positive regulation of mitochondrial translation || 1 0.50 0.09 0.72 0.79 0.13 0.27 -0.47 -0.44 0.48 -0.19 -0.37 0.07 0.28 -0.10 -0.33 0.32
7789 || orf19.4391 || || || Ortholog of C. dubliniensis CD36 : Cd36_28730, Candida tropicalis MYA-3404 : CTRG_00749 and Candida albicans WO-1 : CAWG_01683 || 1 1.30 1.33 1.30 1.53 0.19 0.78 -0.62 -0.80 0.43 -0.29 -0.31 0.23 0.31 -0.15 -0.93 0.84
7790 || orf19.1548 || || || Ortholog(s) have role in mRNA splicing, via spliceosome and U4/U6 x U5 tri-snRNP complex localization || 1 0.47 0.60 0.96 0.74 0.04 0.63 -0.24 -0.35 0.14 -0.58 -0.38 0.18 0.24 0.11 -0.22 0.20
7791 || orf19.56 || ARG2 || || Putative enzyme of arginine biosynthesis; transcription of genes of arginine biosynthesis pathway, except for ARG2, is induced upon phagocytosis by macrophage || 1 0.55 0.56 0.88 0.74 0.37 0.16 -0.00 -0.27 0.38 -0.53 -0.23 -0.00 0.49 -0.08 -0.47 0.20
7792 || orf19.530 || || || Protein with a UV radiation resistance protein/autophagy-related protein 14 domain; Hap43p-induced gene; mutants are viable || 1 0.86 1.05 1.30 1.09 0.32 0.15 -0.19 -0.32 0.14 -0.22 0.12 0.21 0.86 0.29 -0.54 0.13
7793 || orf19.6024 || || || Ortholog of C. dubliniensis CD36 : Cd36_00770, Candida tenuis NRRL Y-1498 : CANTEDRAFT_112621, Debaryomyces hansenii CBS767 : DEHA2D09812g and Pichia stipitis Pignal : PICST_61958 || 1 0.67 0.94 0.56 0.56 0.55 0.27 -0.34 -0.53 0.19 -0.04 0.07 0.10 0.92 0.28 -0.33 0.14
7794 || orf19.4625 || TOA2 || || Putative TFIIA small subunit; protein abundance decreased in CAI4 strain compared to the SC5314 strain, abundance not affected by reintegration of URA3 in CAI4; flucytosine induced; possibly an essential gene (UAU1 method) || 1 0.12 0.26 0.37 0.58 0.27 0.41 -0.24 -0.30 0.08 0.22 -0.05 0.12 0.33 0.08 0.21 0.33
7795 || orf19.7592 || FAA4 || || Predicted acyl CoA synthase || 1 0.45 0.35 0.63 0.91 0.05 0.17 -0.34 -0.34 0.02 0.22 -0.03 0.18 0.15 -0.00 0.19 0.39
7796 || orf19.5941 || || || Ortholog(s) have role in ER to Golgi vesicle-mediated transport and ER to Golgi transport vesicle, integral to Golgi membrane, integral to endoplasmic reticulum membrane localization || 1 0.17 0.27 0.59 0.77 0.14 0.03 -0.55 -0.41 0.25 -0.11 0.01 -0.07 0.20 -0.01 -0.24 -0.02
7797 || orf19.6847 || || || Putative tRNA U44 2'-O-methyltransferase; virulence-group-correlated expression; induced during oral infection; mutants have reduced ability to damage oral epithelial cells; early-stage flow model biofilm induced || 1 0.07 0.09 0.95 0.74 0.41 0.32 -0.61 -0.58 0.62 0.01 0.10 -0.09 0.61 0.02 -0.02 0.19
7798 || orf19.3205 || MPRL36 || || Mitochondrial ribosomal protein of the large subunit; rat catheter biofilm induced || 1 0.36 0.01 1.15 1.29 0.17 0.91 -0.74 -0.64 0.98 0.56 -0.29 0.40 0.28 0.05 -0.00 -0.01
7799 || orf19.3691 || TIM21 || || Component of the Translocase of the Inner Mitochondrial membrane (TIM23 complex); for protein import into mitochondria; Hap43, ketoconazole-repressed; Spider biofilm repressed || 1 0.31 0.38 1.02 0.92 -0.17 0.21 -0.22 -0.56 0.52 0.21 -0.62 0.36 0.21 0.07 -0.10 -0.09
7800 || orf19.1727 || PMC1 || || Vacuolar calcium P-type ATPase; transcript regulated by calcineurin and fluconazole; mutant shows increased resistance to fluconazole, lithium; increased sensitivity to calcium; Spider biofilm induced || 1 0.48 0.37 0.86 0.98 0.06 0.17 -0.23 -0.57 0.39 -0.19 -0.43 -0.11 0.52 0.10 0.32 0.01
7801 || orf19.3132 || || || Predicted endoplasmic reticulum zinc transporter; induced by nitric oxide || 1 0.09 0.23 0.74 0.74 -0.14 0.56 -0.49 -0.63 0.34 -0.09 -0.53 -0.00 0.28 0.43 0.12 0.03
7802 || orf19.5976 || || || Protein of unknown function; ortholog of S. cerevisiae Urn1; downregulated by fluphenazine treatment, in azole-resistant strains that overexpress CDR1 and CDR2 or MDR1 || 1 0.58 0.15 0.74 1.18 0.08 0.58 -0.26 -0.42 0.27 -0.10 -0.51 -0.06 0.18 0.60 -0.17 0.12
7803 || orf19.3117 || CSA2 || || Extracellular-associated protein; repressed by Rim101 at pH 8; regulated by Tsa1, Tsa1B in minimal media at 37 deg; induced by ketoconazole, nitric oxide, Hap43; required for normal RPMI biofilm formation; Bcr1 induced in RPMI || 1 0.18 -0.05 1.36 1.24 -0.13 1.01 -0.83 -1.02 0.57 0.06 -0.69 0.18 -0.02 0.01 -0.68 0.82
7804 || orf19.2429 || || || Protein of unknown function; induced by alpha pheromone in SpiderM medium || 1 0.31 0.06 0.97 1.25 0.36 -0.21 -0.22 -0.08 0.01 -0.71 -1.08 -0.73 -0.57 0.05 -0.33 0.03
7805 || orf19.3734 || GEF2 || || Member of the voltage chloride channel family; Hap43p-repressed gene || 1 0.25 0.41 0.88 0.99 0.69 0.13 -0.09 -0.18 0.63 -0.06 -0.57 -0.30 -0.58 0.03 -0.17 -0.01
7806 || orf19.3237 || || || Ortholog(s) have cytosol, mitochondrion, nucleus localization || 1 0.54 0.36 0.53 0.83 0.40 0.01 0.27 -0.14 0.28 -0.47 -0.60 -0.08 -0.25 -0.23 0.17 0.17
7807 || orf19.2072 || || || Ortholog(s) have (R)-carnitine transmembrane transporter activity, choline transmembrane transporter activity, ethanolamine transmembrane transporter activity || 1 0.34 0.30 0.43 1.02 0.29 0.28 -0.14 -0.19 0.05 -0.39 -0.58 -0.16 -0.46 -0.42 0.35 -0.09
7808 || orf19.1653 || || || Has domain(s) with predicted integral to membrane localization || 1 0.38 0.24 0.58 0.74 -0.11 -0.10 -0.48 -0.28 -0.51 -0.57 -0.11 -0.71 0.01 0.03 -0.23 0.14
7809 || orf19.4654 || || || Protein of unknown function; Spider biofilm induced || 1 1.29 1.40 1.65 1.88 0.07 -1.41 -1.02 -0.98 -0.66 -1.02 -1.17 -1.25 0.83 0.09 -0.46 0.42
7810 || orf19.2350 || || || Protein similar to S. cerevisiae Yor378w; MFS family transporter; transposon mutation affects filamentous growth; null mutants are viable; fungal-specific (no human or murine homolog) || 1 0.48 0.46 1.21 0.91 0.17 -0.42 -0.29 -0.44 0.16 -0.42 -0.47 -0.61 0.42 -0.18 -0.34 0.32
7811 || orf19.1653 || || || Has domain(s) with predicted integral to membrane localization || 1 0.63 0.78 0.90 0.90 0.37 0.17 -0.41 -0.18 -0.03 -0.46 -0.04 -0.63 0.43 0.27 -0.15 0.17
7812 || orf19.3748 || || || Protein of unknown function; orf19.3747 and orf19.3748 are short, overlapping ORFs in intergenic region between 2 oligopeptide transporter-encoding genes; flow model biofilm induced || 1 0.47 0.74 0.64 0.73 0.17 0.09 -0.70 -0.47 0.34 -0.38 -0.20 -0.47 0.45 -0.47 -0.37 0.29
7813 || orf19.7030 || SSR1 || || Beta-glucan associated ser/thr rich cell-wall protein with a role in cell wall structure; GPI anchor; similar mRNA abundance in yeast-form and germ tubes; detected at germ tube plasma membrane; repressed in cells treated with Congo Red || 1 0.32 0.43 0.98 -0.14 0.07 -0.51 -0.70 0.06 -0.42 -0.78 -0.53 0.50 -0.31 0.05 -0.11
7814 || orf19.1756 || GPD1 || || Glycerol-3-phosphate dehydrogenase; glycerol biosynthesis; regulated by Efg1; regulated by Tsa1, Tsa1B under H2O2 stress conditions; Sflow model and Spider biofilm induced || 1 0.33 0.55 0.63 0.55 0.10 -0.16 -0.16 -0.65 0.24 -0.80 -0.59 -0.58 0.46 0.20 -0.56 0.60
7815 || orf19.1365 || || || Putative monooxygenase; mutation confers hypersensitivity to toxic ergosterol analog; constitutive expression independent of MTL or white-opaque status || 1 0.47 0.79 0.88 0.52 -0.48 0.32 -0.06 -0.72 0.42 -0.34 -0.73 -0.29 0.41 0.09 -0.67 0.65
7816 || orf19.6484 || || || Ortholog of C. parapsilosis CDC317 : CPAR2_808370, C. dubliniensis CD36 : Cd36_72070, Candida orthopsilosis Co 90-125 : CORT_0C00800 and Candida albicans WO-1 : CAWG_05577 || 1 1.31 1.75 0.92 2.23 0.04 -0.32 -0.20 -0.13 0.82 -0.37 -0.70 -0.36 -0.06 -0.65 -0.96 0.77
7817 || orf19.1002 || || || Protein of unknown function; Hap43-repressed gene || 1 0.37 0.59 0.57 0.64 -0.27 0.01 0.13 -0.12 0.17 -0.17 -0.71 -0.13 -0.13 0.14 0.01 0.17
7818 || orf19.1738 || UGP1 || || UTP-glucose-1-phosphaturidyl transferase; localizes to yeast, not hyphal cell surface; Hog1-repressed; stationary phase enriched; induced in oralpharyngeal candidasis; rat catheter biofilm repressed; Bcr1-repressed in RPMI a/a biofilms || 1 0.42 0.32 0.52 0.58 -0.12 -0.14 -0.18 -0.11 0.01 -0.27 -0.32 0.12 -0.05 0.24 -0.03 -0.06
7819 || orf19.1751 || SPT23 || || Protein involved in regulation of unsaturated fatty acid biosynthesis; controls the expression of the Ole1p delta-9-fatty acid desaturase || 1 0.42 0.49 0.77 0.80 0.08 -0.03 -0.21 -0.05 -0.03 -0.13 -0.10 0.01 -0.07 0.12 -0.03 0.43
7820 || orf19.6927 || PEP8 || || Protein similar to S. cerevisiae Pep8p, which is involved in retrograde transport; transposon mutation affects filamentous growth || 1 0.45 0.34 0.33 0.25 0.05 -0.01 -0.11 0.11 -0.02 -0.25 -0.05 -0.00 -0.21 0.21 -0.01 0.20
7821 || orf19.4107 || || || Exopolyphosphatase, hydrolyzes inorganic polyphosphate (poly P) into Pi residues; Spider biofilm repressed || 1 0.59 0.52 0.16 0.35 0.09 0.13 -0.01 0.03 -0.06 -0.28 -0.05 -0.27 0.03 -0.30 -0.32 0.17
7822 || orf19.7396 || || || Protein of unknown function; Spider biofilm induced; Hap43-repressed || 1 2.34 2.27 1.49 0.85 0.62 1.57 -0.46 -0.67 -0.17 -1.98 -1.00 -0.63 0.53 -0.36 -1.50 0.50
7823 || orf19.7396 || || || Protein of unknown function; Spider biofilm induced; Hap43-repressed || 1 2.04 1.93 1.20 0.28 0.59 1.19 -0.74 -0.79 -0.65 -2.03 -1.17 -1.14 0.35 -0.54 -1.71 0.27
7824 || orf19.4175 || TOK1 || || Outwardly rectifying, noisily gated potassium channel; modulates sensitivity to human salivary histatin (Hst5); very similar to S. cerevisiae Tok1p; Bcr1-repressed in RPMI a/a biofilms || 1 0.28 0.37 0.68 0.25 -0.02 0.81 0.06 -0.12 0.09 -0.09 -0.49 -0.33 -0.49 0.17 -0.79 0.16
7825 || orf19.1433 || || || Protein of unknown function; Hap43-repressed; colony morphology-related gene regulation by Ssn6; Spider biofilm induced || 1 0.62 0.79 0.93 -0.14 -0.01 0.74 -0.52 -0.98 -0.26 -1.11 -2.10 -0.84 -1.21 -0.02 -1.28 0.42
7826 || orf19.1433 || || || Protein of unknown function; Hap43-repressed; colony morphology-related gene regulation by Ssn6; Spider biofilm induced || 1 1.40 1.34 1.19 0.63 0.30 0.76 -0.30 -0.43 0.06 -0.74 -1.80 -0.78 -0.61 -0.13 -0.85 0.37
7827 || orf19.6038 || UGA32 || || Predicted Zn(II)2Cys6 transcription factor; has similarity to S. cerevisiae Uga3, a transcription factor involved in the regulation of gamma-aminobutyrate metabolism genes; rat catheter biofilm induced || 1 0.67 0.60 0.76 0.30 -0.05 0.39 -0.42 -0.10 0.14 -0.66 -0.51 -0.45 -0.40 -0.58 -0.77 -0.07
7828 || orf19.3432 || || || Predicted membrane transporter, member of the drug:proton antiporter (12 spanner) (DHA1) family, major facilitator superfamily (MFS); induced by nitric oxide || 1 1.67 1.07 0.82 1.05 -0.27 0.43 -0.32 -1.05 0.87 -0.93 -0.85 -0.98 -1.04 -0.68 -1.23 -0.17
7829 || orf19.5520 || ASG7 || || a-cell specific protein of unknown function; two predicted transmembrane domains; member of conserved Mcm1 regulon; induced by alpha pheromone in SpiderM medium || 1 1.81 1.87 1.05 0.81 -1.14 -0.17 -0.32 -1.03 -1.41 -1.47 0.04 -2.30 -1.42 -1.87 0.33
7830 || orf19.6038 || UGA32 || || Predicted Zn(II)2Cys6 transcription factor; has similarity to S. cerevisiae Uga3, a transcription factor involved in the regulation of gamma-aminobutyrate metabolism genes; rat catheter biofilm induced || 1 0.76 0.73 0.76 0.29 0.16 0.75 -0.30 -0.14 0.58 -0.17 -0.17 -0.40 -0.85 -0.48 -1.05 -0.43
7831 || orf19.4947 || || || Mitochondrial membrane protein of unknown function; Spider biofilm induced || 1 0.58 0.72 0.88 -0.08 0.40 0.89 -0.19 -0.35 0.71 -0.17 -1.15 -0.51 -0.69 -0.39 -0.58 -0.74
7832 || orf19.1668 || || || Protein of unknown function; expression downregulated in an ssr1 null mutant || 1 0.49 0.44 0.19 -0.09 0.75 0.85 -0.13 -0.18 -0.00 -0.05 -0.58 -0.14 -0.11 0.11 -0.85 -0.18
7833 || orf19.5884 || || || Putative nucleolar preribosomal-associated protein; decreased transcription is observed upon benomyl treatment or in an azole-resistant strain that overexpresses MDR1; Spider biofilm induced || 1 0.12 0.10 0.46 0.46 0.34 0.80 -0.34 -0.07 0.09 0.25 -0.27 -0.22 -0.23 0.03 -0.25 0.12
7834 || orf19.7274 || || || Predicted ORF in retrotransposon Zorro2 with similarity to retroviral reverse transcriptase proteins || 1 0.12 0.27 0.32 0.48 0.55 0.49 -0.65 -0.28 0.08 -0.05 -0.38 -0.24 -0.34 -0.26 -0.38 0.41
7835 || orf19.1043 || || || Ortholog(s) have lysophosphatidic acid acyltransferase activity and role in cellular response to cadmium ion, cellular triglyceride homeostasis, detoxification of cadmium ion, lipid particle organization, protein targeting to vacuole || 1 0.73 0.64 0.97 0.58 1.84 1.40 -1.59 -0.88 -0.33 -0.41 -1.10 -0.23 -0.81 -0.06 -1.46 0.08
7836 || orf19.3446 || || || Ortholog(s) have Ran GTPase binding activity, role in protein import into nucleus and nucleus localization || 1 0.62 0.59 0.84 0.68 1.52 1.11 -0.77 -0.13 -0.67 -0.03 -0.09 -0.48 -0.57 0.31 -0.43 -0.20
7837 || orf19.2487 || || || Protein with a predicted phosphoribulokinase/uridine kinase domain; Spider biofilm induced || 1 0.80 0.82 0.47 0.43 0.70 0.99 -0.64 -0.47 -0.72 0.01 -0.47 -0.89 -0.47 -0.27 -0.27 0.36
7838 || orf19.2487 || || || Protein with a predicted phosphoribulokinase/uridine kinase domain; Spider biofilm induced || 1 0.66 0.87 0.49 0.52 0.27 0.70 -0.65 -0.34 -0.51 0.22 -0.62 -0.72 -0.63 -0.15 -0.48 0.13
7839 || orf19.1187 || CPH2 || || Myc-bHLH transcription factor; promotes hyphal growth; directly regulates Tec1 to induce hypha-specific genes; probably homodimeric, phosphorylated; required for colonization of the mouse GI tract; rat catheter and Spider biofilm induced || 1 1.38 1.31 0.22 -0.22 0.63 0.88 -1.24 -0.94 -0.24 -0.23 -1.04 -0.48 -0.67 -0.48 -0.19 -0.55
7840 || orf19.1187 || CPH2 || || Myc-bHLH transcription factor; promotes hyphal growth; directly regulates Tec1 to induce hypha-specific genes; probably homodimeric, phosphorylated; required for colonization of the mouse GI tract; rat catheter and Spider biofilm induced || 1 1.30 1.15 0.91 -0.29 0.71 1.23 -1.26 -1.01 -0.54 -0.43 -1.01 -0.13 -0.73 -0.67 -0.18 0.02
7841 || orf19.2488 || FAL1 || || eIF4A subfamily of DEAD-box ATP-dependent RNA helicases; predicted nucleolar protein required for maturation of 18S rRNA; Spider biofilm induced || 1 0.62 0.49 0.14 -0.20 0.63 0.96 -0.61 -0.76 -0.93 0.31 -0.33 -0.02 -0.57 -0.47 0.11 -0.12
7842 || orf19.4569 || || || Ortholog of C. dubliniensis CD36 : Cd36_42100, Debaryomyces hansenii CBS767 : DEHA2C14850g, Pichia stipitis Pignal : PICST_52615 and Spathaspora passalidarum NRRL Y-27907 : SPAPADRAFT_58608 || 1 0.59 0.23 -0.05 0.77 0.25 0.49 -0.32 -0.48 -0.23 0.29 -0.96 -0.62 0.23 -0.26 -0.25
7843 || orf19.3445 || HOC1 || || Protein with similarity to mannosyltransferases; similar to S. cerevisiae Hoc1p and C. albicans Och1p || 1 0.49 0.38 -0.00 0.27 0.32 0.08 -0.18 -0.36 -0.23 -0.02 -0.78 -0.32 -0.19 -0.01 -0.49 -0.32
7844 || orf19.7306 || || || Aldo-keto reductase; increased transcript associated with MDR1 overexpression, benomyl or long-term fluconazole treatment; overexpression does not affect drug or oxidative stress sensitivity; stationary phase enriched; flow biofim repressed || 1 0.52 0.59 -0.25 0.38 0.75 1.03 -0.43 -0.59 0.06 -0.25 -1.67 -0.87 -0.26 0.29 -0.39 -0.19
7845 || orf19.1647 || || || Ortholog(s) have role in ascospore wall assembly || 1 0.82 0.75 0.33 0.55 0.58 0.69 -0.23 -0.28 -0.69 0.26 -1.46 -0.65 0.07 0.97 -0.79 0.35
7846 || orf19.1942 || SGE1 || || Putative multidrug resistance factor; induced in low iron; regulated by Sef1, Sfu1, and Hap43 || 1 0.12 0.31 0.33 0.30 0.04 0.07 -0.56 -0.25 0.04 -0.17 -1.30 -0.57 0.09 0.43 -0.25 0.10
7847 || orf19.5915 || DUR35 || || Putative urea transporter || 1 0.26 0.32 0.20 0.59 0.72 0.36 -0.58 -1.18 -0.34 -0.56 -1.79 0.23 -0.25 -1.24
7848 || orf19.1523 || FMO1 || || Putative oxidoreductase; mutation confers hypersensitivity to toxic ergosterol analog, and to amphotericin B || 1 0.48 0.33 0.35 1.23 -0.13 1.29 -0.82 -1.86 -0.26 -0.62 -2.72 -1.00 0.08 -1.76 -1.26
7849 || orf19.460 || CEK2 || || MAP kinase required for wild-type efficiency of mating; component of the signal transduction pathway that regulates mating; ortholog of S. cerevisiae Fus3; induced by Cph1, pheromone; transposon mutation affects filamentous growth || 1 0.76 0.79 1.18 0.86 0.59 0.05 -0.08 -0.40 0.54 0.18 -3.49 -2.01 0.07 0.97 -0.98 -1.77
7850 || orf19.460 || CEK2 || || MAP kinase required for wild-type efficiency of mating; component of the signal transduction pathway that regulates mating; ortholog of S. cerevisiae Fus3; induced by Cph1, pheromone; transposon mutation affects filamentous growth || 1 0.67 0.92 0.92 0.70 0.64 -0.04 0.18 -0.37 0.16 0.15 -3.48 -2.97 0.23 0.90 -1.21 -2.44
7851 || orf19.6021 || IHD2 || || Protein of unknown function; induced during hyphae development; induced in low iron; Spider biofilm induced || 1 0.14 0.42 0.03 0.24 -0.19 -0.28 -0.34 -0.67 -0.04 -0.17 -1.19 -0.70 0.47 -0.17 -0.51 -1.46
7852 || orf19.3282 || BMT3 || || Beta-mannosyltransferase; adds 2nd beta-mannose to the acid-stable fraction of cell wall phosphopeptidomannan, elongation of beta-mannose chains on the phosphopeptidomannan acid-labile fraction; Hap43-induced; Spider biofilm induced || 1 0.43 0.39 0.58 0.69 -0.38 0.38 -0.38 -0.38 0.04 0.17 -1.73 -0.48 0.22 0.28 -0.11 -1.25
7853 || orf19.3282 || BMT3 || || Beta-mannosyltransferase; adds 2nd beta-mannose to the acid-stable fraction of cell wall phosphopeptidomannan, elongation of beta-mannose chains on the phosphopeptidomannan acid-labile fraction; Hap43-induced; Spider biofilm induced || 1 0.40 0.25 0.07 -0.11 -0.37 -0.05 -0.42 -0.64 -0.37 -0.02 -2.24 -0.72 0.31 0.13 -0.14 -1.32
7854 || orf19.4772 || SSU81 || || Predicted adaptor protein involved in activation of MAP kinase-dependent signaling pathways; links response to oxidative stress to morphogenesis and cell wall biosynthesis; caspofungin repressed || 1 0.25 0.14 0.52 0.28 -0.63 -0.41 -0.85 -0.98 -0.20 0.15 -1.84 -0.84 -0.03 0.27 -0.12 -0.98
7855 || orf19.2062 || SOD4 || || Cu and Zn-containing superoxide dismutase; role in response to host innate immune ROS; regulated on white-opaque switch; ciclopirox olamine induced; caspofungin repressed; SOD1,4,5,6 gene family; yeast-associated; Spider biofilm induced || 1 0.18 0.22 0.70 0.85 -0.13 -0.77 -0.61 -0.81 -0.67 -1.20 -1.47 -2.12 0.56 1.43 -0.22 -1.69
7856 || orf19.7111.1 || SOD3 || || Cytosolic manganese-containing superoxide dismutase; protects against oxidative stress; repressed by ciclopirox olamine, induced during stationary phase when SOD1 expression is low; Hap43-repressed; Spider and flow model biofilm induced || 1 0.75 0.63 1.76 1.34 -1.12 0.14 -1.25 -3.94 -0.04 -4.36 -5.89 -5.28 2.90 1.11 -0.21 -5.07
7857 || orf19.7111.1 || SOD3 || || Cytosolic manganese-containing superoxide dismutase; protects against oxidative stress; repressed by ciclopirox olamine, induced during stationary phase when SOD1 expression is low; Hap43-repressed; Spider and flow model biofilm induced || 1 0.62 0.39 1.65 1.34 -1.28 0.37 -1.15 -3.60 0.00 -4.24 -5.37 -5.91 2.48 1.16 -0.38 -5.31
7858 || orf19.2157 || DAC1 || || N-acetylglucosamine-6-phosphate (GlcNAcP) deacetylase; N-acetylglucosamine utilization; required for wild-type hyphal growth and virulence in mouse systemic infection; gene and protein are GlcNAc-induced; Spider biofilm induced || 1 0.34 0.23 0.70 0.45 0.17 0.51 -1.27 -1.12 -0.61 -1.45 -2.17 -2.89 0.76 0.41 -0.80 -2.44
7859 || orf19.2157 || DAC1 || || N-acetylglucosamine-6-phosphate (GlcNAcP) deacetylase; N-acetylglucosamine utilization; required for wild-type hyphal growth and virulence in mouse systemic infection; gene and protein are GlcNAc-induced; Spider biofilm induced || 1 0.37 0.26 1.28 0.75 -0.15 0.39 -1.04 -0.82 -0.71 -1.23 -2.19 -2.53 0.73 0.94 -0.90 -2.07
7860 || orf19.2157 || DAC1 || || N-acetylglucosamine-6-phosphate (GlcNAcP) deacetylase; N-acetylglucosamine utilization; required for wild-type hyphal growth and virulence in mouse systemic infection; gene and protein are GlcNAc-induced; Spider biofilm induced || 1 0.26 0.21 1.23 0.84 -0.08 0.51 -1.75 -1.35 -1.45 -1.33 -3.14 -2.84 0.61 0.40 -1.41 -2.36
7861 || orf19.2157 || DAC1 || || N-acetylglucosamine-6-phosphate (GlcNAcP) deacetylase; N-acetylglucosamine utilization; required for wild-type hyphal growth and virulence in mouse systemic infection; gene and protein are GlcNAc-induced; Spider biofilm induced || 1 0.28 0.04 0.89 0.76 -0.47 0.17 -1.80 -1.44 -1.34 -1.47 -3.43 -3.38 0.66 1.11 -1.53 -2.78
7862 || orf19.2157 || DAC1 || || N-acetylglucosamine-6-phosphate (GlcNAcP) deacetylase; N-acetylglucosamine utilization; required for wild-type hyphal growth and virulence in mouse systemic infection; gene and protein are GlcNAc-induced; Spider biofilm induced || 1 0.06 -0.10 0.97 0.69 -0.50 0.31 -1.85 -1.36 -1.37 -1.48 -3.85 -3.27 0.37 1.02 -1.61 -2.61
7863 || orf19.1607 || ALR1 || || Putative transporter of divalent cations; hyphal-induced expression; rat catheter biofilm induced || 1 0.32 0.31 1.04 1.21 -0.48 0.04 -0.39 -1.20 -1.12 -0.97 -1.71 -1.67 0.70 0.50 -1.15 -2.03
7864 || orf19.1607 || ALR1 || || Putative transporter of divalent cations; hyphal-induced expression; rat catheter biofilm induced || 1 0.30 0.29 1.41 1.46 -0.03 0.26 -0.28 -0.67 -0.65 -0.87 -1.04 -1.21 0.71 0.59 -0.47 -1.46
7865 || orf19.2564 || || || Putative nucleolar protein; implicated in ribosome biogenesis; rat catheter biofilm repressed || 1 -0.19 -0.16 0.37 0.30 -0.23 0.46 -0.34 -0.56 -0.18 -0.46 -0.69 -0.43 0.16 -0.24 -0.35 -1.00
7866 || orf19.204 || || || Ortholog of C. dubliniensis CD36 : Cd36_23180, Candida tropicalis MYA-3404 : CTRG_01968 and Candida albicans WO-1 : CAWG_05983 || 1 -0.05 -0.01 0.29 0.29 -0.26 0.11 -0.78 -0.76 -0.61 -0.55 -1.50 -0.55 0.01 0.11 -0.52 -1.14
7867 || orf19.6196 || || || Component of the SWI/SNF and RSC chromatin remodeling complexes; suggested role in chromosome maintenance; Spider biofilm induced || 1 0.07 0.14 1.15 0.66 -0.54 0.40 -0.91 -1.15 -0.47 -0.68 -1.12 -0.83 -0.06 -0.08 -0.82 -1.50
7868 || orf19.1325 || ECM38 || || Putative gamma-glutamyltransferase; alkaline upregulated; Spider biofilm induced; possibly an essential gene, disruptants not obtained by UAU1 method || 1 -0.25 0.04 0.64 0.55 -0.06 0.05 -0.68 -0.80 0.00 -0.71 -1.00 -0.75 0.07 -0.14 -0.31 -0.92
7869 || orf19.7450 || || || Ortholog(s) have role in cytokinesis, septin ring assembly and cellular bud neck septin ring localization || 1 0.04 0.07 0.24 0.41 -0.10 -0.08 -0.50 -0.42 -0.02 -0.44 -0.70 -0.33 -0.22 -0.06 -0.23 -0.52
7870 || orf19.4504 || || || Has domain(s) with predicted oxidoreductase activity, transferase activity, transferring acyl groups other than amino-acyl groups, zinc ion binding activity and role in oxidation-reduction process || 1 -0.24 -0.20 1.54 1.71 -0.19 0.63 -0.83 -1.46 -0.81 -1.16 -2.99 -0.90 0.30 -0.31 -1.00 -0.79
7871 || orf19.4504 || || || Has domain(s) with predicted oxidoreductase activity, transferase activity, transferring acyl groups other than amino-acyl groups, zinc ion binding activity and role in oxidation-reduction process || 1 -0.15 -0.28 1.03 1.17 -0.52 0.18 -0.66 -1.12 -1.02 -0.98 -2.52 -1.64 0.22 0.02 -1.02 -0.88
7872 || orf19.4476 || || || Protein with a NADP-dependent oxidoreductase domain; transcript induced by ketoconazole; rat catheter and Spider biofilm induced || 1 0.52 0.55 1.34 1.54 0.19 0.94 -1.67 -2.16 -0.97 -1.15 -5.33 -3.74 1.15 -0.49 -1.91 -1.52
7873 || orf19.695 || RGS2 || || Protein of RGS superfamily; mutants are viable; rat catheter and Spider biofilm induced || 1 0.21 0.28 0.01 0.22 -0.19 0.13 -0.61 -0.84 -0.29 -0.62 -1.55 -1.04 0.74 -0.58 -0.45 -1.07
7874 || orf19.695 || RGS2 || || Protein of RGS superfamily; mutants are viable; rat catheter and Spider biofilm induced || 1 0.34 0.50 0.31 -0.02 -0.01 0.40 -0.37 -0.67 -0.39 -0.44 -1.28 -1.51 0.68 -0.56 -0.46 -0.76
7875 || orf19.695 || RGS2 || || Protein of RGS superfamily; mutants are viable; rat catheter and Spider biofilm induced || 1 0.50 0.48 0.16 0.09 0.14 0.40 -0.54 -0.56 -0.34 -0.41 -1.01 -1.14 0.71 -0.43 -0.25 -1.14
7876 || orf19.695 || RGS2 || || Protein of RGS superfamily; mutants are viable; rat catheter and Spider biofilm induced || 1 0.57 0.71 0.35 0.45 0.22 0.17 -0.42 -0.58 -0.10 -0.39 -1.16 -1.10 0.85 -0.51 -0.06 -1.52
7877 || orf19.695 || RGS2 || || Protein of RGS superfamily; mutants are viable; rat catheter and Spider biofilm induced || 1 0.74 0.61 0.29 0.27 0.26 0.46 -0.27 -0.45 -0.18 -0.54 -1.03 -0.62 1.08 -0.14 -0.03 -0.80
7878 || orf19.1822 || UME6 || || Zn(II)2Cys6 transcription factor; role in hyphal extension, virulence, adherence to plastic; filament induced; regulated by Nrg1/Tup1/Rfg1, alkaline conditions; expression promotes highly filamentous biofilms; rat catheter biofilm induced || 1 1.16 1.30 0.61 0.82 0.03 0.18 -0.43 -0.62 -0.21 -0.09 -1.44 -1.16 0.94 -0.93 -0.57 -1.18
7879 || orf19.6021 || IHD2 || || Protein of unknown function; induced during hyphae development; induced in low iron; Spider biofilm induced || 1 0.71 0.35 0.91 1.13 0.12 0.16 -0.06 -0.34 0.02 -0.09 -1.11 -0.39 0.66 -0.09 0.22 -1.16
7880 || orf19.5992 || WOR2 || || Zn(II)2Cys6 transcription factor; regulator of white-opaque switching; required for maintenance of opaque state; Hap43-induced || 1 0.41 0.64 0.78 0.87 -0.08 -0.20 -0.20 -0.48 0.28 -0.12 -1.00 -0.69 1.01 0.30 0.28 -0.88
7881 || orf19.2724 || || || Protein of unknown function; flow model, rat catheter and Spider biofilm induced; Hap43-repressed || 1 1.65 1.62 1.26 1.52 -0.46 0.11 0.23 -2.14 -0.14 -0.21 -3.56 -2.58 1.88 0.14 0.63 -3.25
7882 || orf19.2724 || || || Protein of unknown function; flow model, rat catheter and Spider biofilm induced; Hap43-repressed || 1 1.49 1.47 1.20 1.28 -0.62 0.01 0.33 -2.17 -0.42 -0.36 -3.62 -2.77 1.91 -0.08 0.40 -3.22
7883 || orf19.7053 || GAC1 || || Putative regulatory subunit of ser/thr phosphoprotein phosphatase 1; fluconazole-induced; caspofungin repressed; transcript induced by Mnl1 under weak acid stress; regulated by Nrg1, Tup1; Spider and flow model biofilm induced || 1 0.37 0.37 1.11 0.37 0.26 0.85 -1.37 -1.65 -0.02 -0.43 -4.11 -2.72 0.38 0.27 -0.51 -4.12
7884 || orf19.7053 || GAC1 || || Putative regulatory subunit of ser/thr phosphoprotein phosphatase 1; fluconazole-induced; caspofungin repressed; transcript induced by Mnl1 under weak acid stress; regulated by Nrg1, Tup1; Spider and flow model biofilm induced || 1 0.59 0.55 1.15 0.46 0.69 1.05 -1.27 -1.40 0.05 -0.44 -4.35 -2.83 0.67 0.01 0.35 -4.51
7885 || orf19.7053 || GAC1 || || Putative regulatory subunit of ser/thr phosphoprotein phosphatase 1; fluconazole-induced; caspofungin repressed; transcript induced by Mnl1 under weak acid stress; regulated by Nrg1, Tup1; Spider and flow model biofilm induced || 1 0.77 0.88 1.31 0.39 0.83 0.85 -0.85 -1.05 0.16 -0.48 -3.95 -2.95 0.84 0.38 0.43 -4.70
7886 || orf19.7053 || GAC1 || || Putative regulatory subunit of ser/thr phosphoprotein phosphatase 1; fluconazole-induced; caspofungin repressed; transcript induced by Mnl1 under weak acid stress; regulated by Nrg1, Tup1; Spider and flow model biofilm induced || 1 1.10 0.98 1.67 0.93 0.99 1.27 -0.67 -0.68 0.33 -0.12 -3.65 -2.41 0.97 0.32 0.59 -3.99
7887 || orf19.7053 || GAC1 || || Putative regulatory subunit of ser/thr phosphoprotein phosphatase 1; fluconazole-induced; caspofungin repressed; transcript induced by Mnl1 under weak acid stress; regulated by Nrg1, Tup1; Spider and flow model biofilm induced || 1 1.13 1.11 1.50 0.73 1.30 1.32 -0.51 -0.57 0.19 -0.32 -3.59 -2.44 1.02 0.23 1.00 -4.29
7888 || orf19.4082 || DDR48 || || Immunogenic stress-associated protein; filamentation regulated; induced by benomyl/caspofungin/ketoconazole or in azole-resistant strain; Hog1, farnesol, alkaline repressed; stationary phase enriched; Spider, flow model biofilm induced || 1 1.49 1.45 1.18 1.64 -0.69 -1.42 -0.25 -1.13 -4.27 -3.84 0.49 -0.93 -0.04 -2.94
7889 || orf19.2030 || || || Plasma membrane-associated protein; induced in cyr1 or ras1 mutant; induced by hypoxia, ketoconazole and during growth in the mouse cecum; induced in oralpharyngeal candidasis; Spider biofilm induced || 1 0.54 0.43 0.17 0.31 0.67 0.56 0.01 -0.96 -0.39 -0.89 -1.77 -1.39 -0.03 -0.07 0.59 -1.26
7890 || orf19.2030 || || || Plasma membrane-associated protein; induced in cyr1 or ras1 mutant; induced by hypoxia, ketoconazole and during growth in the mouse cecum; induced in oralpharyngeal candidasis; Spider biofilm induced || 1 0.88 0.81 0.31 0.32 0.89 0.47 0.35 -0.80 -0.47 -1.15 -1.69 -1.71 0.36 -0.13 0.52 -1.31
7891 || orf19.2474 || PRC3 || || Putative carboxypeptidase Y precursor; transcript regulated by Nrg1 and Mig1; regulated by Gcn2 and Gcn4 || 1 0.50 0.32 0.64 0.37 -0.11 0.33 0.50 -0.58 0.24 -0.86 -1.38 -0.88 0.35 -0.56 -0.30 -0.81
7892 || orf19.5532 || || || Protein of unknown function; Spider biofilm induced || 1 0.64 0.94 1.01 0.13 -0.06 0.41 -0.15 -0.78 0.12 -0.61 -1.25 -1.09 0.23 -0.53 -0.82 -0.63
7893 || orf19.5532 || || || Protein of unknown function; Spider biofilm induced || 1 0.54 0.95 1.17 0.19 -0.04 0.90 -0.38 -0.90 0.28 -0.65 -2.00 -1.23 0.29 -0.07 -1.31 -0.90
7894 || orf19.1479 || || || Ortholog of the mitochondria localized S. cerevisiae Pib2 protein of unknown function; has a FYVE zinc finger domain; Spider biofilm induced || 1 0.48 0.48 0.27 0.45 0.09 0.42 -0.34 -0.19 -0.00 -0.26 -0.60 -0.65 0.29 -0.07 -0.31 -0.27
7895 || orf19.3610 || || || Protein of unknown function; upregulation correlates with clinical development of fluconazole resistance; regulated by Sef1, Sfu1, and Hap43 || 1 0.00 0.00 0.22 0.14 0.02 -0.06 -0.30 -0.47 0.04 -0.87 -0.64 -0.28 0.05 0.08 -0.11 -0.03
7896 || orf19.4372 || || || Predicted transmembrane transporter; rat catheter and Spider biofilm induced || 1 0.13 0.16 0.62 0.39 0.31 0.14 -0.24 -0.37 0.19 -1.06 -0.33 -0.41 -0.17 0.03 -0.40 0.13
7897 || orf19.5524 || || || Ortholog of C. dubliniensis CD36 : Cd36_62790, C. parapsilosis CDC317 : CPAR2_601680, Candida tenuis NRRL Y-1498 : cten_CGOB_00252 and Debaryomyces hansenii CBS767 : DEHA2A06622g || 1 0.04 0.14 0.67 0.09 0.11 0.02 -0.40 -0.45 0.09 -0.68 -0.36 -0.33 0.02 -0.34 -0.29 0.17
7898 || orf19.3956 || || || Ortholog(s) have glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity and role in endoplasmic reticulum organization, glutaminyl-tRNAGln biosynthesis via transamidation || 1 0.25 0.07 0.46 0.33 0.24 -0.01 -0.37 -0.38 0.26 -0.46 -0.40 -0.07 -0.04 -0.17 -0.45 -0.01
7899 || orf19.5504 || || || Ortholog of C. dubliniensis CD36 : Cd36_73400, C. parapsilosis CDC317 : CPAR2_703180, Candida tenuis NRRL Y-1498 : CANTEDRAFT_104803 and Debaryomyces hansenii CBS767 : DEHA2A04466g || 1 -0.05 -0.04 0.48 0.46 0.02 -0.03 -0.50 -0.40 0.20 -0.65 -0.54 -0.08 -0.06 0.12 -0.13 -0.04
7900 || orf19.7181 || || || Ortholog of C. dubliniensis CD36 : Cd36_73670, C. parapsilosis CDC317 : CPAR2_702370, Candida tenuis NRRL Y-1498 : CANTEDRAFT_119320 and Debaryomyces hansenii CBS767 : DEHA2G16632g || 1 -0.19 -0.04 0.25 0.20 0.03 -0.04 -0.50 -0.54 0.16 -0.35 -0.43 -0.19 0.04 0.02 -0.22 -0.13
7901 || orf19.6094 || VPS53 || || Ortholog(s) have role in Golgi to vacuole transport, retrograde transport, endosome to Golgi and GARP complex localization || 1 -0.33 -0.12 0.21 0.28 -0.00 0.01 -0.58 -0.41 -0.03 -0.52 -0.41 -0.18 0.03 -0.19 -0.09 -0.18
7902 || orf19.6557 || || || Protein with a predicted fatty acid amide hydrolase I domain; induced by Mnl1 under weak acid stress || 1 -0.14 -0.17 0.31 0.59 -0.03 0.01 -0.43 -0.62 -0.05 -0.87 -0.43 -0.16 -0.06 -0.15 -0.30 -0.24
7903 || orf19.5133 || ZCF29 || || Zn(II)2Cys6 transcription factor; mutants sensitive to caffeine and menadione, resistant to fenpropimorph; Hap43-repressed; mutants have decreased CFU in mouse kidneys and defects in filamentous growth; Spider biofilm induced || 1 -0.13 0.07 0.75 0.72 0.47 0.35 -0.85 -1.10 -0.20 -1.29 -0.60 -0.07 0.08 -0.22 -0.09 0.15
7904 || orf19.6997 || ATO5 || || Putative fungal-specific transmembrane protein || 1 -0.27 -0.14 0.99 0.61 0.03 0.22 -0.80 -0.78 -0.07 -0.67 -0.24 -0.53 0.25 -0.14 -0.32 0.03
7905 || orf19.7044 || RIM15 || || Ortholog(s) have protein kinase activity and role in age-dependent response to oxidative stress involved in chronological cell aging, conidiophore development, hyphal growth, protein phosphorylation, regulation of meiosis || 1 -0.08 -0.20 0.52 0.38 0.22 0.13 -0.35 -0.32 0.09 -0.49 -0.38 -0.25 -0.11 -0.25 0.26 0.02
7906 || orf19.6440 || || || Ortholog(s) have ubiquitin-protein ligase activity, role in ubiquitin-dependent protein catabolic process and endoplasmic reticulum membrane, nuclear inner membrane localization || 1 -0.29 -0.41 0.34 0.35 0.24 0.47 -0.28 -0.58 0.06 -0.98 -0.59 -0.34 -0.34 -0.27 -0.02 0.08
7907 || orf19.2851 || || || Putative ornithine transport protein; localized to the mitochondrial membrane || 1 -0.00 -0.12 0.74 0.31 -0.03 0.35 -0.40 -0.46 0.22 -0.84 -0.61 -0.46 -0.45 -0.87 -0.53 -0.02
7908 || orf19.211 || || || Predicted homeodomain-like transcription factor; also has a metal-binding Ada DNA repair protein domain; Spider biofilm induced || 1 -0.19 -0.29 0.50 0.45 -0.15 0.39 -0.29 -0.62 -0.62 -0.75 -0.46 -0.46 -0.26 -0.38 -0.05 -0.05
7909 || orf19.1156 || FUS1 || || Membrane protein required for mating; ortholog of S. cerevisiae Fus1; transcript induced by Cph1 in cells homozygous for the MTLa locus; alpha factor induced || 1 -0.07 0.06 0.53 0.72 -0.62 0.07 -0.26 -0.30 -0.45 -0.86 -0.89 -0.16 -0.27 -0.46 -0.43 0.25
7910 || orf19.3621 || || || Possible pseudogene; similar to Ywp1p; ORF extended upstream from the initiating Met of orf19.3621 has a stop codon in the region corresponding to the Ywp1p signal peptide; disruption causes no apparent phenotype; no expression detected || 1 0.18 0.14 0.60 0.97 -0.42 0.41 -0.58 -0.47 -0.60 -1.05 -1.01 -0.11 -0.86 -0.20 -0.08 0.13
7911 || orf19.1009 || || || Ortholog of Candida albicans WO-1 : CAWG_01857 || 1 -0.01 0.11 0.79 0.90 -0.64 0.72 -0.74 -0.73 -0.43 -0.58 -0.75 0.09 -0.40 -0.59 -0.34 -0.14
7912 || orf19.5117 || OLE1 || || Fatty acid desaturase, essential protein involved in oleic acid synthesis; required for aerobic hyphal growth and chlamydospore formation; subject to hypoxic regulation; fluconazole-induced; caspofungin repressed; Hap43p-induced || 1 0.20 0.26 0.62 0.32 -0.15 0.27 -0.84 -0.73 -0.11 -0.75 -0.73 -0.20 -0.41 -0.54 -0.97 0.21
7913 || orf19.7207 || DOA4 || || Ortholog of S. cerevisiae Doa4;, a ubiquitin hydrolase involved in recycling ubiquitin from proteasome-bound ubiquitinated intermediates; oxidative stress-induced via Cap1; mutants are viable || 1 -0.00 0.04 0.44 0.37 -0.13 -0.02 -0.49 -0.57 -0.21 -0.53 -0.63 -0.04 -0.61 -0.32 -0.32 0.17
7914 || orf19.3910 || || || Has domain(s) with predicted RNA binding, ribonuclease T2 activity || 1 0.61 0.35 0.51 0.66 -0.12 0.24 -0.87 -1.12 -0.71 -1.78 -1.19 -0.49 -0.87 -1.32 -0.47 0.20
7915 || orf19.4059 || || || Ortholog(s) have role in actin cortical patch localization, arginine transport, cellular protein localization, cellular response to heat, endocytosis, late endosome to vacuole transport and lysine transport, more || 1 0.02 -0.04 0.35 0.29 0.12 0.43 -0.43 -0.53 -0.19 -1.01 -0.49 -0.12 -0.14 -0.49 -0.16 0.20
7916 || CaalfMp14 || NAD4 || || Subunit 4 of NADH:ubiquinone oxidoreductase (NADH:ubiquinone dehydrogenase), a multisubunit enzyme complex (complex I) of the mitochondrial inner membrane that catalyzes the first step in mitochondrial respiration || 1 0.12 0.13 0.23 0.72 0.08 0.67 -0.42 -0.57 -0.33 -0.74 -0.45 -0.09 -0.38 -0.16 -0.72 0.06
7917 || orf19.6720 || || || P-Loop domain-containing protein of unknown function; transposon mutation affects filamentous growth; Spider biofilm induced || 1 0.09 0.19 0.48 1.09 -0.07 0.43 -0.34 -0.45 -0.01 -1.17 -0.74 -0.24 -0.30 0.04 -0.46 -0.29
7918 || orf19.1191 || || || Ortholog(s) have ubiquitin-protein ligase activity and role in ER-associated ubiquitin-dependent protein catabolic process || 1 0.08 -0.11 0.48 0.32 0.07 0.40 -0.61 -0.31 0.25 -0.34 -0.11 -0.02 -0.14 -0.27 0.10 0.12
7919 || orf19.4901 || || || Predicted methyltransferase; Spider biofilm induced || 1 0.26 -0.23 0.19 0.87 0.62 0.66 -0.73 -1.09 0.05 -0.99 -0.37 -0.00 -0.53 -0.58 0.29 0.24
7920 || orf19.2073 || || || Protein with a multidrug and toxin extrusion protein domain; induced by Mnl1 under weak acid stress || 1 0.12 0.10 0.33 0.57 0.55 0.69 -0.55 -0.57 0.24 -0.66 -0.45 0.06 -0.19 -0.58 0.08 -0.02
7921 || orf19.1990 || SNX4 || || Putative sorting nexin; induced during the mating process || 1 0.38 0.20 0.88 0.91 0.56 0.82 -0.87 -0.72 0.04 -0.47 -0.83 0.00 -0.11 -0.37 0.19 0.13
7922 || orf19.1763 || IFR1 || || Predicted oxidoreductase/dehydrogenase; induced by nitric oxide; rat catheter and Spider biofilm induced || 1 0.33 0.14 0.97 1.28 0.46 1.21 -0.80 -0.99 -0.62 -1.07 -0.93 0.09 -0.90 -0.55 0.15 0.28
7923 || orf19.4921 || || || Ortholog of C. dubliniensis CD36 : Cd36_12030 and Candida albicans WO-1 : CAWG_00152 || 1 0.36 -0.04 1.09 1.33 0.21 0.89 -0.61 -0.56 -0.38 -0.77 -0.43 -0.01 -0.04 -0.48 0.09 0.40
7924 || orf19.3908 || MRV8 || || Protein of unknown function; Spider biofilm induced || 1 -0.06 0.11 1.32 1.11 0.66 0.90 -0.66 -0.79 -0.31 -0.89 -0.38 0.23 -0.27 -0.83 -0.03 0.21
7925 || orf19.7258 || DDI1 || || Putative DNA damage inducible v-SNARE binding protein; macrophage/pseudohyphal-repressed || 1 0.15 0.07 0.51 0.62 0.37 0.77 -0.60 -0.49 0.05 -0.40 -0.22 0.20 -0.36 -0.56 0.22 0.25
7926 || orf19.3176 || RIM21 || || Plasma membrane pH-sensor involved in the Rim101 pH response pathway; required for processing and activation of Rim101 and for alkaline pH-induced hyphal growth; Spider biofilm induced || 1 0.06 0.08 0.54 0.37 0.59 0.74 -0.47 -0.63 -0.08 -0.24 -0.27 0.29 -0.40 -0.86 0.24 0.52
7927 || orf19.5205 || || || Protein of unknown function; Hap43-repressed gene || 1 -0.04 -0.12 0.38 0.49 0.39 0.73 -0.48 -0.36 -0.01 -0.72 -0.39 0.04 -0.19 -1.00 -0.27 -0.09
7928 || orf19.313 || DAL4 || || Putative allantoin permease; fungal-specific (no human or murine homolog) || 1 -0.03 0.17 0.79 0.63 0.66 0.96 -0.51 -0.51 0.01 -1.03 -0.38 -0.35 0.21 -0.63 -0.19 -0.19
7929 || orf19.7166 || || || Predicted mitochondrial cardiolipin-specific phospholipase; upregulated in an azole-resistant strain that overexpresses MDR1; induced by Mnl1 under weak acid stress; rat catheter and Spider biofilm induced || 1 0.18 0.43 1.17 0.81 0.28 1.59 -0.47 -0.78 -0.12 -1.41 -0.88 -0.49 0.31 -0.62 -0.51 -0.05
7930 || orf19.7550 || IFA14 || || Putative LPF family protein; Plc1-regulated; induced by alpha pheromone in SpiderM medium || 1 -0.10 -0.10 0.63 0.21 0.26 1.21 -0.46 -0.53 -0.07 -0.87 -0.54 -0.09 0.04 -0.50 -0.13 0.15
7931 || orf19.3910 || || || Has domain(s) with predicted RNA binding, ribonuclease T2 activity || 1 0.35 0.31 0.71 0.40 0.35 0.39 -0.41 -0.54 -0.00 -1.04 -0.44 -0.25 -0.08 -0.84 -0.29 0.12
7932 || orf19.3910 || || || Has domain(s) with predicted RNA binding, ribonuclease T2 activity || 1 0.79 0.85 1.11 1.04 0.12 0.53 -0.56 -0.89 0.05 -0.99 -0.84 -0.26 -0.19 -1.17 -0.40 0.31
7933 || orf19.2149 || || || Putative sulfate permease; S. cerevisiae ortholog YPR003C localizes to the endoplasmic reticulum; regulated by Sef1p-, Sfu1p-, and Hap43p || 1 0.33 0.27 0.41 0.27 0.64 0.80 -0.10 -0.39 -0.10 -0.76 -0.16 -0.19 -0.39 -1.01 -0.03 0.05
7934 || orf19.4248 || || || Ortholog of S. cerevisiae YLR118C (alias Apt1); acyl-protein thioesterase responsible for depalmitoylation of Gpa1 in S. cerevisiae; regulated by Gcn4; repressed in response to amino acid starvation (3AT); rat catheter biofilm repressed || 1 0.67 0.48 0.35 0.46 0.58 0.71 -0.35 -0.15 -0.19 -0.43 -0.07 -0.40 -0.73 -0.36 -0.58 -0.30
7935 || orf19.201 || || || Protein of unknown function; unmerged from orf19.202 in a revision of Assembly 21 || 1 0.97 0.84 0.83 0.70 1.08 1.00 -0.74 -0.21 -0.17 -0.50 0.09 -0.17 -0.97 -0.48 -0.21 -0.19
7936 || orf19.201 || || || Protein of unknown function; unmerged from orf19.202 in a revision of Assembly 21 || 1 0.36 0.39 0.74 0.61 0.58 1.00 -0.22 -0.18 -0.03 -0.50 0.05 -0.23 -0.31 -0.38 -0.22 -0.45
7937 || CaalfMp03 || NAD1 || || Subunit 6 of NADH:ubiquinone oxidoreductase (NADH:ubiquinone dehydrogenase), a multisubunit enzyme complex (complex I) of the mitochondrial inner membrane that catalyzes the first step in mitochondrial respiration || 1 0.37 0.40 0.45 0.80 0.89 1.11 -0.47 -0.41 -0.12 -0.69 -0.23 0.00 -0.37 -0.39 0.01 -0.26
7938 || orf19.201 || || || Protein of unknown function; unmerged from orf19.202 in a revision of Assembly 21 || 1 0.15 0.42 0.83 0.63 0.59 0.89 -0.64 -0.40 0.00 -0.68 -0.27 -0.42 -0.42 -0.70 -0.55 -0.21
7939 || orf19.4546 || HOL4 || || Putative ion transporter; alkaline induced by Rim101; Plc1-regulated; caspofungin repressed; rat catheter and Spider biofilm induced || 1 -0.09 0.19 0.62 0.39 0.36 0.56 -0.30 -0.19 -0.11 -0.47 -0.28 -0.29 -0.72 -0.76 -0.35 -0.06
7940 || CaalfMp01 || COX2 || || Subunit II of cytochrome c oxidase, which is the terminal member of the mitochondrial inner membrane electron transport chain; one of three mitochondrially-encoded subunits || 1 0.60 0.36 0.68 0.87 0.39 0.91 -0.21 -0.49 -0.86 -1.27 -0.47 -0.26 -0.20 -1.01 -0.22 -0.35
7941 || CaalfMp06 || ATP6 || || Subunit 6 of the F0 sector of mitochondrial F1F0 ATP synthase, which is a large, evolutionarily conserved enzyme complex required for ATP synthesis || 1 0.59 0.52 0.63 1.18 0.61 1.37 -0.53 -0.76 -0.79 -1.27 -0.39 0.12 -0.13 -0.65 0.05 -0.26
7942 || orf19.1763 || IFR1 || || Predicted oxidoreductase/dehydrogenase; induced by nitric oxide; rat catheter and Spider biofilm induced || 1 0.52 0.42 0.72 0.95 0.84 1.42 -1.61 -1.84 -0.54 -1.70 -1.25 -0.24 -1.23 -1.70 -0.35 0.04
7943 || orf19.7475 || PHO81 || || Protein involved in regulation of hyphal development; required for response to farnesoic acid; possibly adherence-induced || 1 1.26 1.04 0.80 0.98 0.90 1.47 -1.52 -1.79 -0.85 -1.07 -1.07 -0.06 -1.33 -1.23 -0.81 -0.49
7944 || orf19.3922 || || || Possible pyrimidine 5' nucleotidase; protein present in exponential and stationary growth phase yeast cultures; Hap43p-repressed gene || 1 1.06 1.03 0.80 0.87 1.26 1.60 -1.45 -1.59 -1.25 -1.39 -0.08 -0.35 -1.87 -1.28 -0.18 -0.11
7945 || orf19.3922 || || || Possible pyrimidine 5' nucleotidase; protein present in exponential and stationary growth phase yeast cultures; Hap43p-repressed gene || 1 1.09 0.97 0.94 0.74 1.30 1.66 -1.31 -1.15 -1.01 -1.36 -0.09 -0.41 -1.66 -1.28 -0.25 0.11
7946 || orf19.3922 || || || Possible pyrimidine 5' nucleotidase; protein present in exponential and stationary growth phase yeast cultures; Hap43p-repressed gene || 1 0.75 0.62 0.67 0.60 0.85 1.47 -1.11 -1.09 -1.11 -1.25 -0.20 -0.59 -0.56 -1.38 -0.22 -0.36
7947 || orf19.7166 || || || Predicted mitochondrial cardiolipin-specific phospholipase; upregulated in an azole-resistant strain that overexpresses MDR1; induced by Mnl1 under weak acid stress; rat catheter and Spider biofilm induced || 1 0.90 0.98 0.90 0.61 0.91 1.83 -0.76 -2.19 -1.82 -2.54 -1.05 -0.98 -1.32 -1.75 -1.27 -0.23
7948 || orf19.1971 || TRY3 || || RING-finger transcription factor; regulator of yeast form adherence; required for yeast cell adherence to silicone substrate; Spider biofilm induced || 1 0.28 0.16 0.40 0.05 0.82 1.86 -0.67 -2.03 -1.93 -1.64 -0.68 -0.44 -1.15 -0.96 -0.77 0.48
7949 || orf19.1943 || || || Ortholog of C. parapsilosis CDC317 : CPAR2_302610, C. dubliniensis CD36 : Cd36_51070, Candida orthopsilosis Co 90-125 : CORT_0E04770 and Spathaspora passalidarum NRRL Y-27907 : SPAPADRAFT_50634 || 1 0.23 0.19 0.27 0.69 0.12 0.60 -0.24 -0.46 -0.81 -0.36 -0.61 -0.62 -0.47 -0.98 -0.08 -0.06
7950 || orf19.4266 || SPR28 || || Septin; similar to S. cerevisiae meiotic/sporulation septin; mutant has no obvious phenotype; two introns with noncanonical branch site and 5' splice site, respectively; splicing inhibited upon exposure to alpha-factor || 1 -0.11 0.07 0.15 0.37 0.35 0.47 -0.16 -0.28 0.01 -0.00 -0.46 -0.51 -0.26 -0.44 -0.03 -0.15
7951 || orf19.5604 || MDR1 || || Plasma membrane MDR/MFS multidrug efflux pump; methotrexate is preferred substrate; overexpression in drug-resistant clinical isolates confers fluconazole resistance; repressed in young biofilms; rat catheter biofilm induced || 1 -0.20 -0.10 -0.07 0.89 0.52 1.79 -0.97 -1.20 -1.01 -0.50 -1.33 -0.86 -1.35 -1.49 -0.92 -0.75
7952 || orf19.1641 || || || Ortholog(s) have cytosol, extracellular region, nucleus localization || 1 0.02 -0.18 0.75 0.87 1.13 1.81 -1.02 -1.33 -1.00 -0.62 -2.29 -1.82 -1.45 -1.59 -0.41 -0.25
7953 || orf19.5536 || || || Has domain(s) with predicted carbon-nitrogen ligase activity, with glutamine as amido-N-donor, hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides activity || 1 0.11 -0.00 0.73 0.70 0.52 1.38 -0.90 -1.34 -0.57 -0.96 -1.80 -0.78 -0.86 -0.86 -0.38 -0.09
7954 || orf19.1779 || MP65 || || Cell surface mannoprotein; cell-wall glucan metabolism, adhesion; adhesin motif; O-glycosylation; induced by heat, germ tube formation, wall regeneration; mycelial antigen; diagnostic marker; fluconazole-repressed; Spider biofilm induced || 1 0.05 -0.16 0.64 1.13 0.66 0.86 -0.54 -0.63 -0.27 -0.33 -1.04 -0.55 -0.53 -1.14 -0.26 -0.63
7955 || orf19.3080 || || || Ortholog(s) have role in attachment of spindle microtubules to kinetochore, cellular response to nitrogen starvation, cohesin localization to chromatin and double-strand break repair, more || 1 0.12 0.20 0.53 0.58 0.49 0.48 -0.55 -0.25 -0.36 -0.08 -0.70 -0.61 -0.54 -0.79 -0.43 -0.25
7956 || orf19.5823 || SGT2 || || Putative small tetratricopeptide repeat (TPR)-containing protein; protein abundance is affected by URA3 expression in the CAI-4 strain background; Mig1-regulated || 1 0.08 0.05 0.57 0.52 0.22 0.36 -0.31 -0.13 -0.19 0.01 -0.41 -0.37 -0.52 -0.38 -0.20 -0.49
7957 || orf19.1306 || || || Ortholog(s) have cytosol, nucleus localization || 1 0.80 0.60 0.71 0.47 0.40 0.86 -0.45 -0.28 -0.08 -0.05 -1.11 -0.69 -0.57 0.27 -0.60 -0.68
7958 || orf19.7442 || || || Ortholog of C. dubliniensis CD36 : Cd36_86500, C. parapsilosis CDC317 : CPAR2_206120, Candida tenuis NRRL Y-1498 : CANTEDRAFT_100862 and Debaryomyces hansenii CBS767 : DEHA2F17270g || 1 1.29 0.73 1.38 0.77 0.47 1.27 -0.94 -0.93 -0.66 -0.08 -1.24 -0.80 -1.19 -0.48 -1.13 -0.58
7959 || orf19.4001 || || || Ortholog(s) have role in protein insertion into mitochondrial membrane from inner side and extrinsic to mitochondrial inner membrane, mitochondrial matrix localization || 1 0.62 0.58 0.56 0.85 0.55 0.61 -0.49 -0.68 -0.69 -0.63 -0.53 -0.70 0.18 -0.72 0.46 -0.69
7960 || orf19.2693 || GST2 || || Glutathione S transferase; induced by benomyl and in populations of cells exposed to fluconazole over multiple generations; regulated by Nrg1, Tup1; induced by nitric oxide; stationary phase enriched; Spider biofilm induced || 1 1.05 0.83 1.02 1.04 1.40 1.99 -1.04 -0.80 -0.77 -1.43 -1.40 -1.71 -0.38 -1.27 0.71 -1.77
7961 || orf19.7441 || || || Ortholog(s) have role in cellular lipid metabolic process, mRNA export from nucleus, protein export from nucleus and nuclear envelope localization || 1 0.82 0.71 0.45 0.17 0.64 0.77 -0.70 -0.72 -1.06 -0.62 -0.56 -1.07 -0.43 -0.98 -0.58 -0.97
7962 || orf19.7440 || HST6 || || ABC transporter related to mammalian P-glycoproteins; functional homolog of S. cerevisiae Ste6p (a-pheromone transporter); required for mating of MTLa cells; a-type specific, not regulated during white-opaque or yeast-hyphal switching || 1 1.34 1.90 1.68 1.43 1.35 1.86 -0.93 -1.25 -1.66 -0.60 -1.43 -2.25 -1.16 -1.56 -1.09 -1.06
7963 || orf19.7440 || HST6 || || ABC transporter related to mammalian P-glycoproteins; functional homolog of S. cerevisiae Ste6p (a-pheromone transporter); required for mating of MTLa cells; a-type specific, not regulated during white-opaque or yeast-hyphal switching || 1 1.61 1.67 1.68 1.73 2.00 2.12 -1.42 -1.74 -1.73 -0.51 -1.77 -1.96 -1.87 -2.03 -1.45 -1.40
7964 || orf19.1797 || || || D-arabinose 5-phosphate isomerase; has GutQ domain which is associated with phosphosugar binding; other biofilm induced; rat catheter and Spider biofilm induced; F-12/CO2 early biofilm induced || 1 1.08 1.12 0.59 0.80 0.90 1.46 -0.69 -0.84 -0.64 -0.63 -1.45 -1.29 -0.16 -0.01 -0.43 -1.21
7965 || orf19.1797 || || || D-arabinose 5-phosphate isomerase; has GutQ domain which is associated with phosphosugar binding; other biofilm induced; rat catheter and Spider biofilm induced; F-12/CO2 early biofilm induced || 1 0.82 0.60 0.64 0.79 0.68 1.13 -0.87 -0.82 -1.13 -1.12 -1.31 -1.30 -0.40 -0.43 -0.54 -1.00
7966 || orf19.6235 || || || Protein of unknown function; Spider biofilm induced || 1 0.85 0.46 0.86 0.44 0.41 1.04 -0.01 -0.57 -0.60 -0.77 -0.73 -0.76 -0.09 -0.38 -0.34 -0.47
7967 || orf19.1007 || KCS1 || || Putative bZIP transcription factor; Spider biofilm induced || 1 1.45 1.34 0.77 0.58 1.07 2.03 -0.65 -1.10 -1.21 -1.17 -1.51 -1.57 -0.12 -1.14 -1.23 -1.28
7968 || orf19.1007 || KCS1 || || Putative bZIP transcription factor; Spider biofilm induced || 1 1.30 1.21 0.77 0.37 1.00 2.22 -0.57 -1.16 -0.99 -1.22 -1.27 -1.20 -0.37 -0.46 -0.91 -0.79
7969 || orf19.1007 || KCS1 || || Putative bZIP transcription factor; Spider biofilm induced || 1 1.46 1.12 0.99 0.63 1.50 2.37 -0.47 -0.91 -1.09 -1.04 -1.20 -1.18 0.01 -0.82 -0.81 -1.08
7970 || orf19.1007 || KCS1 || || Putative bZIP transcription factor; Spider biofilm induced || 1 1.00 1.27 0.64 0.37 1.36 2.13 -0.21 -0.58 -0.88 -0.98 -0.59 -1.03 -0.11 -0.52 -0.52 -0.87
7971 || orf19.7441 || || || Ortholog(s) have role in cellular lipid metabolic process, mRNA export from nucleus, protein export from nucleus and nuclear envelope localization || 1 0.99 0.92 0.87 0.77 0.69 1.20 -0.41 -0.87 -0.78 0.05 -0.19 -0.86 -0.35 -0.45 -0.42 -0.39
7972 || orf19.3778 || || || Protein with a predicted role in ribosome biogenesis; mutation confers hypersensitivity to 5-fluorocytosine (5-FC), 5-fluorouracil (5-FU); repressed in core stress response; repressed by prostaglandins; Hap43-induced || 1 0.18 0.19 0.72 0.59 0.57 0.62 -0.37 -0.36 0.25 0.03 -0.48 -0.58 0.05 -0.42 -0.15 -0.26
7973 || orf19.3906 || MRV6 || || Ortholog of Candida albicans WO-1 : CAWG_04796 || 1 0.06 0.21 1.12 0.90 0.28 1.05 -0.63 -0.51 0.16 -0.15 -0.93 -0.50 -0.17 -0.76 -1.00 -0.18
7974 || orf19.5604 || MDR1 || || Plasma membrane MDR/MFS multidrug efflux pump; methotrexate is preferred substrate; overexpression in drug-resistant clinical isolates confers fluconazole resistance; repressed in young biofilms; rat catheter biofilm induced || 1 0.51 0.59 0.90 1.56 1.10 1.73 -0.72 -0.85 0.08 -0.15 -0.85 -0.51 -0.29 -1.01 -0.88 -0.70
7975 || orf19.4363 || SGD1 || || Predicted small ribosomal subunit biogenesis protein; repressed in core stress response; transcript increases in populations of cells exposed to fluconazole over multiple generations; Spider biofilm induced || 1 0.38 0.54 1.04 1.14 0.68 1.22 -0.55 -0.95 -0.00 -0.28 -0.63 -0.50 0.19 -0.56 -0.46 -0.45
7976 || orf19.3784 || || || Ortholog of C. dubliniensis CD36 : Cd36_44580 || 1 0.65 0.52 0.84 0.57 0.83 1.63 -0.42 -1.05 0.09 -0.70 -1.13 -0.41 0.40 -0.92 -0.74 -0.68
7977 || orf19.3783 || || || Protein of unknown function; rat catheter biofilm induced || 1 0.47 0.30 1.13 0.80 0.55 1.31 -0.63 -1.09 0.07 -0.69 -1.10 -0.67 0.21 -0.95 -0.93 -0.54
7978 || orf19.3784 || || || Ortholog of C. dubliniensis CD36 : Cd36_44580 || 1 0.62 0.54 0.92 0.84 0.44 1.46 -0.23 -0.60 0.31 -0.41 -0.93 -0.90 0.39 -0.97 -1.23 -0.99
7979 || orf19.3783 || || || Protein of unknown function; rat catheter biofilm induced || 1 0.32 0.23 0.47 0.30 0.39 1.26 -0.90 -1.09 -0.22 -0.67 -1.25 -0.64 -0.12 -1.03 -1.05 -0.45
7980 || orf19.4189 || || || Has domain(s) with predicted hydrolase activity || 1 0.96 0.98 1.47 1.09 1.28 2.46 -2.33 -2.73 -0.64 -1.87 -2.34 -3.97 -0.00 -3.17 -2.52 -2.54
7981 || orf19.6405 || || || Protein of unknown function; decreased transcription is observed in an azole-resistant strain that overexpresses MDR1 || 1 -0.06 0.01 0.13 0.08 0.22 0.25 -0.24 -0.47 0.17 -0.46 -0.29 -0.64 0.24 -0.61 -0.44 -0.28
7982 || orf19.6831 || PRP5 || || Putative pre-mRNA processing RNA-helicase; induced upon adherence to polystyrene; rat catheter and Spider biofilm induced || 1 -0.24 0.17 0.37 -0.03 0.79 0.92 -0.88 -1.68 -0.73 -0.19 -0.99 -0.76 -0.12 -0.11 -0.59 -0.78
7983 || orf19.3665 || SET6 || || Ortholog of S. cerevisiae Set6, a SET domain protein of unknown function; Hap43-induced; rat catheter and Spider biofilm induced || 1 0.32 0.41 0.56 0.16 0.89 1.85 -0.83 -1.68 -1.20 -0.76 -1.38 -0.77 -0.85 -0.30 -0.86 -0.96
7984 || orf19.5678 || || || Has domain(s) with predicted role in peptidyl-diphthamide biosynthetic process from peptidyl-histidine and cytoplasm localization || 1 0.36 0.33 0.54 0.18 1.20 1.49 -0.66 -1.08 -0.80 0.12 -0.70 -0.93 -0.38 -0.56 -0.18 -0.18
7985 || orf19.4173 || || || Ortholog(s) have role in peptidyl-diphthamide biosynthetic process from peptidyl-histidine and cytosol localization || 1 0.00 0.31 0.51 0.08 1.07 1.35 -0.43 -1.17 -1.00 -0.07 -0.63 -0.83 -0.46 -0.93 -0.01 -0.24
7986 || orf19.2404 || || || Ortholog(s) have RNA binding, ribonuclease MRP activity, ribonuclease P activity and role in intronic box C/D snoRNA processing, mRNA cleavage, rRNA processing, tRNA processing || 1 0.19 0.12 0.34 0.13 0.47 0.74 -0.55 -0.87 -0.65 0.03 -0.65 -0.27 -0.25 -0.46 0.17 -0.35
7987 || orf19.6347 || || || Pre-mRNA splicing factor; important for catalytic step II of pre-mRNA splicing; possible role in cell cycle progression; Spider biofilm induced || 1 0.14 0.07 0.21 -0.05 0.96 1.21 -0.43 -0.80 -0.82 -0.20 -0.59 -0.47 0.02 -0.32 0.31 -0.49
7988 || orf19.480 || || || Protein of unknown function; rat catheter and Spider biofilm induced || 1 0.34 0.25 0.19 0.28 0.82 1.04 -0.16 -0.73 -0.76 0.15 -0.48 -0.42 0.18 -0.29 0.50 -0.36
7989 || orf19.2827 || || || Ortholog(s) have structural constituent of cytoskeleton activity || 1 0.42 0.49 0.56 0.91 0.42 0.64 -0.50 -0.67 -0.01 -0.11 -0.24 -0.10 0.35 -0.26 0.58 -0.10
7990 || orf19.6276 || || || Protein of unknown function; rat catheter biofilm repressed || 1 0.41 0.33 0.62 0.68 0.59 0.67 -0.53 -0.65 -0.18 -0.35 -0.35 -0.15 0.29 -0.32 0.53 0.14
7991 || orf19.7350 || RCT1 || || Fluconazole-induced protein; Ras1, Cyr1 repressed and Efg1 induced; regulated by Nrg1, Tup1, Tbf1, Ssn6; induced in oralpharyngeal candidasis; rat catheter biofilm repressed || 1 1.02 0.99 1.06 -0.94 -1.46 -0.45 -0.84 -0.72 -0.18 0.04 -0.89 0.76 -0.26
7992 || orf19.1764 || || || Protein of unknown function; rat catheter and Spider biofilm induced || 1 0.51 0.35 0.41 0.25 1.05 1.09 -0.68 -0.78 -0.64 -0.58 -0.95 -0.50 -0.23 -0.68 0.71 -0.38
7993 || orf19.1035 || WAR1 || || Zn(II)2Cys6 transcription factor; plays a role in resistance to weak organic acids; required for yeast cell adherence to silicone substrate; Spider biofilm induced || 1 0.34 0.37 0.69 0.50 1.20 0.83 -0.75 -0.88 -0.67 -0.62 -0.64 -0.29 0.07 -0.42 0.54 -0.26
7994 || orf19.712 || KIP1 || || Non-essential kinesin from the bipolar (Kinesis-5) family; involved in formation of the mitotic spindle || 1 0.07 0.19 0.47 0.07 0.47 0.59 -0.57 -0.61 -0.29 -0.39 -0.44 -0.31 0.33 -0.41 0.51 -0.08
7995 || orf19.3635 || || || Ortholog of C. dubliniensis CD36 : Cd36_22580, C. parapsilosis CDC317 : CPAR2_406960, Candida tenuis NRRL Y-1498 : CANTEDRAFT_113677 and Debaryomyces hansenii CBS767 : DEHA2D03608g || 1 0.08 0.15 0.52 0.53 0.68 0.78 -1.05 -1.00 -0.29 -0.49 -0.63 -0.27 -0.00 -0.64 0.68 -0.44
7996 || orf19.6457 || || || Ortholog of S. cerevisiae : YBL086C, C. glabrata CBS138 : CAGL0C01815g, C. dubliniensis CD36 : Cd36_72270, C. parapsilosis CDC317 : CPAR2_702850 and Candida tenuis NRRL Y-1498 : CANTEDRAFT_107537 || 1 0.07 0.25 0.28 0.23 0.22 0.48 -0.46 -0.44 -0.07 -0.13 -0.36 -0.13 0.27 -0.30 0.31 -0.33
7997 || orf19.3633 || || || Ortholog(s) have role in purine nucleobase catabolic process and cytosol, nucleus localization || 1 0.07 0.34 0.13 0.52 0.80 0.93 -0.95 -1.05 -0.31 -0.62 -0.44 0.08 0.28 -0.44 0.49 -0.11
7998 || orf19.3215 || || || Putative plasma membrane protein; in S. cerevisiae it is localized to the cell bud and mating projection membrane; repressed by alpha pheromone in SpiderM medium || 1 0.50 0.38 0.88 0.65 0.62 0.78 -0.44 -0.78 -0.61 -0.90 -0.81 -0.42 0.21 -0.18 0.26 0.03
7999 || orf19.1035 || WAR1 || || Zn(II)2Cys6 transcription factor; plays a role in resistance to weak organic acids; required for yeast cell adherence to silicone substrate; Spider biofilm induced || 1 -0.04 0.25 0.08 0.62 0.99 1.03 -1.26 -1.47 -1.09 -0.65 -1.18 -0.47 0.06 -0.47 0.17 -0.29
8000 || orf19.3176 || RIM21 || || Plasma membrane pH-sensor involved in the Rim101 pH response pathway; required for processing and activation of Rim101 and for alkaline pH-induced hyphal growth; Spider biofilm induced || 1 0.02 0.25 0.33 0.21 0.39 0.50 -0.65 -0.50 -0.22 -0.42 -0.51 -0.38 -0.13 -0.67 0.07 -0.25
8001 || orf19.3633 || || || Ortholog(s) have role in purine nucleobase catabolic process and cytosol, nucleus localization || 1 0.31 0.06 0.74 0.80 0.34 0.67 -0.75 -0.65 -0.25 -0.43 -0.96 -0.38 0.18 -0.70 0.65 -0.39
8002 || orf19.4135 || PRC2 || || Putative carboxypeptidase; induced by human neutrophils; Spider biofilm induced || 1 0.26 0.26 0.80 1.17 0.52 1.09 -0.64 -0.84 -0.62 -1.42 -0.92 -0.26 -0.24 -1.18 0.77 -0.47
8003 || orf19.4135 || PRC2 || || Putative carboxypeptidase; induced by human neutrophils; Spider biofilm induced || 1 0.48 0.44 1.35 1.49 0.58 1.44 -1.27 -1.64 -1.08 -1.59 -1.63 -0.28 -0.34 -1.10 0.48 -0.07
8004 || orf19.4135 || PRC2 || || Putative carboxypeptidase; induced by human neutrophils; Spider biofilm induced || 1 0.12 0.06 1.18 1.43 0.57 1.46 -1.44 -2.03 -1.39 -2.12 -1.76 -0.69 -0.54 -1.75 0.57 -0.70
8005 || orf19.4135 || PRC2 || || Putative carboxypeptidase; induced by human neutrophils; Spider biofilm induced || 1 -0.08 -0.11 0.62 0.92 0.31 1.29 -1.01 -1.50 -0.83 -1.65 -1.47 -0.40 -0.40 -1.12 0.51 -0.66
8006 || orf19.2480.1 || AUT7 || || Putative autophagosome protein; macrophage/pseudohyphal-repressed; alternatively spliced intron in 5' UTR; Spider biofilm induced || 1 0.38 0.28 1.19 0.76 0.90 1.14 -1.41 -1.98 -0.50 -1.56 -2.20 -0.54 -0.64 -1.40 0.21 -0.98
8007 || orf19.2480.1 || AUT7 || || Putative autophagosome protein; macrophage/pseudohyphal-repressed; alternatively spliced intron in 5' UTR; Spider biofilm induced || 1 0.32 0.23 1.26 0.99 0.61 1.03 -1.17 -1.50 -0.38 -1.60 -1.80 -0.88 -0.51 -1.53 0.12 -1.07
8008 || orf19.7105 || FAR1 || || Protein involved in regulation of pheromone-mediated mating; repressed by A1p and Alpha2p in white-phase cells; null mutant shows no pheromone response in opaque cells; overexpression causes enhanced pheromone response and cell cycle arrest || 1 -0.21 -0.22 0.80 0.71 0.31 0.66 -1.09 -1.13 -0.65 -1.20 -1.22 -0.12 -0.10 -0.47 0.29 -0.42
8009 || orf19.6793 || || || Protein of unknown function; Sef1, Sfu1, and Hap43 regulated; rat catheter and Spider biofilm induced || 1 -0.47 -0.28 1.33 1.47 0.93 0.90 -1.62 -1.96 -0.62 -1.39 -2.55 -0.84 0.18 -1.27 0.60 -1.34
8010 || orf19.6793 || || || Protein of unknown function; Sef1, Sfu1, and Hap43 regulated; rat catheter and Spider biofilm induced || 1 -0.39 -0.23 1.38 1.54 0.97 1.22 -1.64 -1.98 -0.65 -1.28 -2.48 -0.74 0.31 -0.97 0.69 -1.54
8011 || orf19.6793 || || || Protein of unknown function; Sef1, Sfu1, and Hap43 regulated; rat catheter and Spider biofilm induced || 1 -0.02 -0.10 1.75 1.90 1.19 1.08 -1.51 -1.87 -0.56 -1.36 -2.23 -0.76 0.33 -1.10 0.67 -1.28
8012 || orf19.6793 || || || Protein of unknown function; Sef1, Sfu1, and Hap43 regulated; rat catheter and Spider biofilm induced || 1 -0.29 -0.25 1.95 1.85 1.11 1.32 -1.38 -1.87 -0.66 -1.52 -2.40 -1.03 0.02 -0.92 0.54 -1.15
8013 || orf19.6793 || || || Protein of unknown function; Sef1, Sfu1, and Hap43 regulated; rat catheter and Spider biofilm induced || 1 -0.38 -0.47 1.34 1.53 1.07 1.09 -1.59 -1.56 -0.79 -1.59 -2.42 -1.08 0.14 -0.53 0.44 -1.41
8014 || orf19.5622 || GLC3 || || Putative 1,4-glucan branching enzyme; fluconazole-induced; colony morphology-related gene regulation by Ssn6; stationary phase enriched protein || 1 -0.02 -0.25 0.50 0.51 0.08 0.62 -0.47 -0.59 -0.15 -0.77 -1.17 -0.60 0.01 -0.43 0.38 -0.70
8015 || orf19.802 || UGA1 || || Putative GABA transaminase; transcription regulated by Mig1 and Tup1; stationary phase enriched protein; rat catheter and Spider biofilm induced || 1 0.53 0.40 0.85 0.42 0.28 1.45 -0.95 -1.52 -0.21 -0.76 -2.42 -0.97 -0.28 -0.07 0.40 -0.72
8016 || orf19.802 || UGA1 || || Putative GABA transaminase; transcription regulated by Mig1 and Tup1; stationary phase enriched protein; rat catheter and Spider biofilm induced || 1 0.51 0.63 0.79 0.64 0.19 1.38 -1.46 -1.96 -0.37 -0.82 -2.89 -1.39 -0.79 -0.41 0.09 -0.93
8017 || orf19.3606 || || || Ortholog of S. cereviae Sna4 vacuolar outer membrane protein that plays a role in sensitivity to NA+; induced by Mnl1 under weak acid stress || 1 0.68 0.68 0.82 0.85 0.19 1.11 -1.00 -1.40 -0.62 -0.71 -1.18 -0.59 -0.68 -0.25 0.19 -0.15
8018 || orf19.3606 || || || Ortholog of S. cereviae Sna4 vacuolar outer membrane protein that plays a role in sensitivity to NA+; induced by Mnl1 under weak acid stress || 1 0.64 0.50 0.67 0.65 0.12 0.87 -1.18 -1.45 -0.82 -0.88 -1.23 -0.71 -0.60 -0.07 0.22 -0.33
8019 || orf19.3606 || || || Ortholog of S. cereviae Sna4 vacuolar outer membrane protein that plays a role in sensitivity to NA+; induced by Mnl1 under weak acid stress || 1 0.58 0.50 0.66 0.69 0.27 0.83 -1.22 -1.44 -0.91 -0.70 -1.22 -0.81 -0.56 -0.19 0.07 -0.35
8020 || orf19.3606 || || || Ortholog of S. cereviae Sna4 vacuolar outer membrane protein that plays a role in sensitivity to NA+; induced by Mnl1 under weak acid stress || 1 0.56 0.52 0.69 0.57 0.06 0.87 -1.04 -1.28 -0.93 -0.69 -1.28 -0.73 -0.58 -0.11 0.04 -0.34
8021 || orf19.3606 || || || Ortholog of S. cereviae Sna4 vacuolar outer membrane protein that plays a role in sensitivity to NA+; induced by Mnl1 under weak acid stress || 1 0.68 0.54 0.70 0.74 0.21 1.02 -1.05 -1.32 -0.88 -0.70 -1.10 -0.88 -0.42 -0.19 0.15 -0.48
8022 || orf19.2127 || CST5 || || Scaffold protein for the mitogen-activated protein (MAP) kinase cascade that regulates mating; required for opaque mating or white biofilm formation in response to mating pheromone; induced in response to pheromone; Hap43p-repressed || 1 0.31 0.44 1.09 0.73 0.84 1.31 -0.90 -1.15 -0.61 -1.00 -1.47 -1.09 -0.63 -0.25 -0.24 -0.42
8023 || orf19.2127 || CST5 || || Scaffold protein for the mitogen-activated protein (MAP) kinase cascade that regulates mating; required for opaque mating or white biofilm formation in response to mating pheromone; induced in response to pheromone; Hap43p-repressed || 1 0.52 0.57 1.33 1.16 0.57 1.00 -1.02 -0.99 -0.33 -0.76 -1.55 -1.17 -0.67 -0.13 -0.39 -0.43
8024 || orf19.3351 || || || Protein of unknown function; Hap43-induced; Spider biofilm induced || 1 0.40 0.37 1.41 1.45 0.39 1.10 -1.05 -1.10 -0.18 -1.07 -1.89 -0.55 -0.49 -0.35 0.32 -0.29
8025 || orf19.4482 || IFI3 || || Protein of unknown function; constitutive expression independent of MTL or white-opaque status || 1 0.51 0.37 0.98 1.40 -0.01 0.87 -1.00 -1.31 -0.66 -1.33 -2.13 -1.13 -0.75 -0.47 -0.68 -0.13
8026 || orf19.5797 || PLC2 || || Phosphatidylinositol (PtdIns)-specific phospholipase C (PI-PLC); predicted type 2 membrane protein; role in, and regulated by, filamentation, Nrg1 and Tup1; no mouse systemic virulence role; orf19.5797 and orf19.1586 are almost identical || 1 0.24 0.19 0.32 0.28 0.12 0.25 -0.36 -0.23 -0.16 -0.32 -0.44 -0.29 -0.38 0.12 0.05 0.01
8027 || orf19.2946 || HNM4 || || Putative choline permease; fungal-specific (no human or murine homolog) || 1 0.50 0.22 0.99 1.16 0.44 1.45 -0.77 -1.06 -1.54 -1.00 -1.19 -1.19 -0.65 -0.66 -0.07 -0.22
8028 || orf19.5031 || SSK1 || || Response regulator of two-component system; role in oxidative stress response, cell wall biosynthesis, virulence, hyphal growth on solid media; expressed in hyphae and yeast; peroxisomal targeting sequence (PTS1); Spider biofilm induced || 1 -0.12 -0.25 0.64 0.51 0.42 0.65 -1.32 -1.34 -1.25 -0.76 -0.93 -0.73 -0.10 -0.34 0.38 -0.73
8029 || orf19.5031 || SSK1 || || Response regulator of two-component system; role in oxidative stress response, cell wall biosynthesis, virulence, hyphal growth on solid media; expressed in hyphae and yeast; peroxisomal targeting sequence (PTS1); Spider biofilm induced || 1 -0.41 -0.42 0.41 0.59 0.41 0.67 -1.24 -1.30 -1.16 -0.92 -1.23 -0.52 -0.15 0.03 0.41 -0.46
8030 || orf19.5633 || || || F-box domain-containing protein; flow model biofilm induced || 1 -0.38 -0.65 0.59 0.50 0.23 0.63 -1.12 -1.14 -0.79 -0.97 -1.22 -0.73 0.08 0.18 0.48 -0.65
8031 || orf19.5633 || || || F-box domain-containing protein; flow model biofilm induced || 1 -0.58 -0.56 0.35 0.27 0.40 0.81 -0.82 -1.12 -0.87 -1.08 -1.09 -0.78 -0.05 0.26 0.56 -0.47
8032 || orf19.5633 || || || F-box domain-containing protein; flow model biofilm induced || 1 -0.24 -0.56 0.56 0.69 0.54 1.04 -0.74 -0.90 -0.45 -0.93 -1.14 -0.72 0.12 0.25 0.26 -0.64
8033 || orf19.3364 || || || Ortholog of C. parapsilosis CDC317 : CPAR2_403360, Debaryomyces hansenii CBS767 : DEHA2D00814g, Pichia stipitis Pignal : PICST_32156 and Candida guilliermondii ATCC 6260 : PGUG_04611 || 1 0.21 0.17 0.43 0.34 0.53 1.48 -0.63 -0.63 -1.08 -1.23 -0.86 -0.70 -0.32 -0.19 0.31 0.11
8034 || orf19.3364 || || || Ortholog of C. parapsilosis CDC317 : CPAR2_403360, Debaryomyces hansenii CBS767 : DEHA2D00814g, Pichia stipitis Pignal : PICST_32156 and Candida guilliermondii ATCC 6260 : PGUG_04611 || 1 0.24 0.14 0.42 0.49 0.42 1.24 -0.34 -0.18 -0.81 -1.06 -0.73 -0.93 -0.01 -0.43 0.50 -0.07
8035 || orf19.1943 || || || Ortholog of C. parapsilosis CDC317 : CPAR2_302610, C. dubliniensis CD36 : Cd36_51070, Candida orthopsilosis Co 90-125 : CORT_0E04770 and Spathaspora passalidarum NRRL Y-27907 : SPAPADRAFT_50634 || 1 0.05 0.55 0.66 1.11 0.80 1.24 -0.12 -1.12 0.06 -0.40 -1.55 -1.66 -0.44 -0.52 -0.11 -1.11
8036 || orf19.6084 || || || Protein of unknown function; flow model biofilm induced; Spider biofilm induced || 1 0.14 1.24 0.97 1.21 1.21 0.84 -0.35 -0.43 0.23 -0.21 -1.06 -0.52 -0.18 -0.47 0.07 -0.83
8037 || orf19.2616 || UGT51C1 || || UDP-glucose:sterol glucosyltransferase; enzyme of sterol glucoside (membrane-bound lipid) biosynthesis; has UDP-sugar binding domain; activity is UDP-glucose-specific in vitro; enzyme does not use UDP-mannose; Mig1-regulated || 1 0.64 0.60 0.92 1.19 1.09 0.68 -0.33 -0.63 0.20 -0.32 -1.21 -0.54 -0.13 -0.24 0.15 -0.51
8038 || orf19.6196 || || || Component of the SWI/SNF and RSC chromatin remodeling complexes; suggested role in chromosome maintenance; Spider biofilm induced || 1 0.60 0.52 0.58 0.46 1.14 1.10 -0.62 -0.98 -0.31 -0.77 -1.74 -1.00 -0.07 -0.12 0.34 -0.98
8039 || orf19.2616 || UGT51C1 || || UDP-glucose:sterol glucosyltransferase; enzyme of sterol glucoside (membrane-bound lipid) biosynthesis; has UDP-sugar binding domain; activity is UDP-glucose-specific in vitro; enzyme does not use UDP-mannose; Mig1-regulated || 1 0.62 0.82 0.60 0.72 1.02 0.51 -0.44 -0.77 -0.02 -0.28 -1.35 -0.84 -0.35 -0.38 0.50 -0.70
8040 || orf19.4551 || CTN1 || || Carnitine acetyl transferase; required for growth on nonfermentable carbon sources, not for hyphal growth or virulence in mice; induced in macrophage; macrophage/pseudohyphal-repressed after 16 hr; rat catheter, Spider biofilm induced || 1 0.38 0.40 1.11 1.24 1.00 0.68 -0.01 -0.98 -0.18 0.19 -1.75 -0.89 -0.62 -0.19 0.51 -1.03
8041 || orf19.7288 || || || Protein with predicted oxidoreductase and dehydrogenase domains; Hap43-repressed; Spider biofilm induced || 1 0.64 0.49 0.50 0.63 1.08 0.81 -0.23 -0.46 -0.15 0.13 -1.46 -0.31 -0.41 -0.27 0.09 -1.14
8042 || orf19.7288 || || || Protein with predicted oxidoreductase and dehydrogenase domains; Hap43-repressed; Spider biofilm induced || 1 0.51 0.39 0.57 0.61 0.93 0.81 -0.33 -0.51 -0.18 0.12 -1.66 -0.25 -0.74 -0.05 -0.11 -0.77
8043 || orf19.6084 || || || Protein of unknown function; flow model biofilm induced; Spider biofilm induced || 1 0.19 0.37 0.79 0.77 1.53 0.28 -0.76 -1.33 -0.05 0.18 -1.59 -0.46 -0.39 -0.20 -0.10 -0.76
8044 || orf19.559 || FGR14 || || Protein encoded in retrotransposon Zorro3 with similarity to retroviral endonuclease-reverse transcriptase proteins; lacks an ortholog in S. cerevisiae; transposon mutation affects filamentous growth || 1 -0.06 -0.12 0.48 0.34 0.44 0.54 -0.23 -0.16 -0.24 -0.87 -0.68 -0.51 -0.22 -0.54 0.14 -0.47
8045 || orf19.3646 || CTR1 || || Copper transporter; transcribed in low copper; induced Mac1, Tye7, macrophage interaction, alkaline pH via Rim101; 17-beta-estradiol repressed; complements S. cerevisiae ctr1 ctr3 copper transport mutant; flow model/Spider biofilm induced || 1 0.68 0.63 0.41 0.58 0.04 2.00 -0.22 -1.30 -0.78 -1.98 -1.86 -1.58 -0.24 -0.56 -0.07 -1.32
8046 || orf19.3646 || CTR1 || || Copper transporter; transcribed in low copper; induced Mac1, Tye7, macrophage interaction, alkaline pH via Rim101; 17-beta-estradiol repressed; complements S. cerevisiae ctr1 ctr3 copper transport mutant; flow model/Spider biofilm induced || 1 1.04 0.77 0.25 0.21 0.25 2.05 0.02 -1.29 -0.53 -2.14 -1.85 -1.83 -0.15 -0.80 0.14 -1.45
8047 || orf19.3991 || || || Ortholog(s) have role in cellular lipid metabolic process and cytosol localization || 1 0.14 0.02 0.02 0.33 -0.18 0.10 -0.32 -0.42 -0.20 -0.09 -0.21 -0.22 -0.22 -0.71 -0.53 -0.37
8048 || orf19.2467 || PRN1 || || Protein with similarity to pirins; induced by benomyl and in response to alpha pheromone in SpiderM medium; transcript induced by Mnl1 in weak acid stress; rat catheter and Spider biofilm induced || 1 0.18 0.25 0.52 1.30 -0.51 0.20 -0.97 -0.98 -0.74 -0.20 -0.65 -0.78 -0.23 -1.64 -0.89 -0.98
8049 || orf19.1124 || || || Protein of unknown function; flow model biofilm induced; Spider biofilm induced || 1 0.50 0.67 0.92 1.01 -0.57 0.05 -1.15 -1.25 -0.09 -0.33 -1.44 -0.25 -0.23 -1.85 -0.73 -0.60
8050 || orf19.1124 || || || Protein of unknown function; flow model biofilm induced; Spider biofilm induced || 1 0.51 0.48 1.07 1.34 -0.89 0.35 -1.28 -1.70 -0.16 -0.27 -1.30 0.24 -0.09 -1.59 -0.90 -0.15
8051 || orf19.4334 || PGA58 || || Putative GPI-anchored protein; transcription is positively regulated by Tbf1p || 1 0.21 0.09 0.20 0.62 -1.09 -0.01 -1.03 -1.02 -0.34 -0.11 -0.83 0.23 -0.34 -0.75 -1.10 -0.53
8052 || orf19.968 || PGA14 || || Putative GPI-anchored protein; induced during cell wall regeneration; regulated by Ssn6p || 1 0.17 0.08 0.03 0.37 -0.92 0.07 -0.38 -0.54 -0.38 -0.37 -0.47 -0.08 -0.26 -0.37 -0.63 -0.35
8053 || orf19.968 || PGA14 || || Putative GPI-anchored protein; induced during cell wall regeneration; regulated by Ssn6p || 1 0.08 0.02 0.22 0.59 -1.11 -0.07 -0.63 -0.74 -0.49 -0.42 -0.68 -0.38 -0.12 -0.66 -1.07 -0.37
8054 || orf19.246 || || || Predicted metalloendopeptidase; Spider biofilm induced || 1 0.20 0.16 -0.42 0.80 -1.02 0.52 -1.51 -1.64 -1.34 -1.22 -1.71 -0.31 -0.19 -1.62 -0.83 -0.31
8055 || orf19.5461 || || || Ortholog of Candida albicans WO-1 : CAWG_02350 || 1 0.57 0.14 0.35 1.04 -0.38 0.03 -0.58 -0.61 -1.23 -0.71 -0.80 -0.10 -0.17 -0.89 -0.60 -0.27
8056 || orf19.6068 || SVF1 || || Putative survival factor; stationary phase enriched protein; fluconazole-induced; regulated by Gcn4p; repressed in response to amino acid starvation (3-AT treatment); fungal-specific (no human or murine homolog) || 1 0.47 0.45 0.43 0.61 -0.37 0.07 -0.73 -0.51 -0.58 0.15 -0.52 -0.20 -0.58 -0.02 -0.14 -0.15
8057 || orf19.6068 || SVF1 || || Putative survival factor; stationary phase enriched protein; fluconazole-induced; regulated by Gcn4p; repressed in response to amino acid starvation (3-AT treatment); fungal-specific (no human or murine homolog) || 1 0.51 0.35 0.32 0.46 -0.43 -0.04 -0.82 -0.47 -0.75 0.13 -0.62 -0.47 -0.78 -0.19 -0.26 -0.42
8058 || orf19.6068 || SVF1 || || Putative survival factor; stationary phase enriched protein; fluconazole-induced; regulated by Gcn4p; repressed in response to amino acid starvation (3-AT treatment); fungal-specific (no human or murine homolog) || 1 0.69 0.62 0.43 0.44 -0.27 -0.04 -0.78 -0.30 -0.79 0.12 -0.58 -0.28 -0.72 -0.21 -0.36 -0.22
8059 || orf19.3052 || YPT1 || || Functional homolog of S. cerevisiae Ypt1p, which is an essential small Ras-type GTPase involved in protein secretion at ER-to-Golgi; dominant-negative mutation causes SAP secretion defect and accumulation of intracellular secretory vesicles || 1 0.23 0.29 0.24 0.38 -0.03 -0.12 -0.37 -0.08 -0.45 -0.07 -0.18 -0.29 -0.21 -0.27 -0.10 -0.25
8060 || orf19.6068 || SVF1 || || Putative survival factor; stationary phase enriched protein; fluconazole-induced; regulated by Gcn4p; repressed in response to amino acid starvation (3-AT treatment); fungal-specific (no human or murine homolog) || 1 0.61 0.47 0.28 0.24 -0.34 -0.32 -0.78 -0.51 -0.97 -0.08 -0.60 -0.82 -0.58 -0.54 -0.53 -0.62
8061 || orf19.6044 || MOB2 || || Mob1/phocein domain protein of RAM signaling network; cell wall integrity; role in cell separation, cortical actin polarization; required for hyphal growth; phosphorylated by Cdc28 on hyphal induction; activates Cbk1; mRNA binds She3 || 1 0.13 0.19 0.23 0.18 0.06 -0.10 -0.41 -0.13 -0.40 0.10 -0.22 -0.25 -0.34 -0.38 -0.29 -0.26
8062 || orf19.677 || CHO1 || || Putative phosphatidylserine synthase; ortholog of S. cerevisiae CHO1; transposon mutation affects filamentous growth; regulated by Nrg1, Tup1 || 1 1.05 0.61 0.43 0.42 0.11 0.05 -0.65 -0.39 -0.67 -0.39 -0.35 -1.00 -0.42 -0.70 -0.18 -1.37
8063 || orf19.2848 || || || Predicted regulatory subunit of the Atg1 signaling complex; required for vesicle formation during autophagy and the cytoplasm-to-vacuole targeting (Cvt) pathway; Spider biofilm induced || 1 0.26 0.13 0.87 0.43 -0.10 -0.59 -0.59 -1.29 0.07 -0.82 -1.23 -0.23 -0.62 -0.97 -0.54 -0.39
8064 || orf19.2848 || || || Predicted regulatory subunit of the Atg1 signaling complex; required for vesicle formation during autophagy and the cytoplasm-to-vacuole targeting (Cvt) pathway; Spider biofilm induced || 1 0.23 0.32 0.67 0.59 -0.55 -0.47 -0.43 -0.81 -0.03 -1.03 -1.00 -0.38 -0.75 -1.03 -0.41 -0.44
8065 || orf19.1477 || || || Protein of unknown function; possible ER protein; Hap43p-repressed; Spider biofilm induced || 1 0.42 0.31 0.88 0.69 -0.19 -0.30 -0.55 -0.39 0.08 -0.67 -1.10 -0.49 -0.80 -0.79 0.08 -0.60
8066 || orf19.751 || || || Ortholog of C. dubliniensis CD36 : Cd36_04660, Candida tropicalis MYA-3404 : CTRG_04484 and Candida albicans WO-1 : CAWG_00904 || 1 0.04 -0.01 1.03 0.72 0.01 0.63 -0.73 -0.59 -0.33 -0.52 -1.03 -0.73 -0.92 0.06 -0.60 -0.62
8067 || orf19.5338 || GAL4 || || Zn(II)2Cys6 transcription factor; involved in control of glycolysis; ortholog of S. cerevisiae Gal4, but not involved in regulation of galactose utilization genes; caspofungin repressed; Spider biofilm repressed || 1 0.05 -0.01 0.63 1.08 0.16 0.41 -0.57 -0.76 -1.22 -0.70 -0.71 -1.50 0.28 -0.62 -0.80 -0.58
8068 || orf19.5338 || GAL4 || || Zn(II)2Cys6 transcription factor; involved in control of glycolysis; ortholog of S. cerevisiae Gal4, but not involved in regulation of galactose utilization genes; caspofungin repressed; Spider biofilm repressed || 1 0.23 0.25 0.65 1.45 0.03 0.34 -0.48 -0.71 -0.85 -0.44 -0.87 -1.47 0.28 -0.31 -0.71 -1.24
8069 || orf19.6691 || || || Putative ember of the multi-drug and toxin extrusion (MATE) family of the multidrug/oligosaccharidyl-lipid/polysaccharide exporter superfamily; Spider biofilm induced || 1 -0.05 0.02 0.42 0.44 0.16 0.70 -0.14 -0.83 -0.46 0.22 -0.89 -0.51 -0.54 -0.29 -0.35 -0.72
8070 || orf19.4096 || TAZ1 || || Putative lyso-phosphatidylcholine acyltransferase, required for normal phospholipid content of mitochondrial membranes; rat catheter biofilm induced || 1 0.45 0.27 0.63 0.22 0.32 0.69 -0.40 -0.86 -0.41 0.13 -1.00 -0.50 -0.22 -0.86 -0.33 -1.58
8071 || orf19.4096 || TAZ1 || || Putative lyso-phosphatidylcholine acyltransferase, required for normal phospholipid content of mitochondrial membranes; rat catheter biofilm induced || 1 0.37 0.30 0.52 0.31 0.35 0.61 -0.57 -0.89 -0.18 0.41 -0.97 -0.16 -0.09 -0.60 -0.42 -1.39
8072 || orf19.5011 || KAR9 || || Ortholog of S. cerevisiae Kar9; role in mitotic spindle positioning; nonessential; localizes to bud tip, bud neck, hyphal tip; wild-type localization requires actin and microtubule cytoskeleton; induced by alpha factor || 1 0.18 0.23 0.42 0.62 0.31 0.49 -0.51 -0.67 -0.27 0.24 -0.93 -0.25 -0.28 -0.58 -0.52 -0.70
8073 || orf19.4029 || || || Ortholog(s) have role in ribosomal large subunit assembly and cytosolic ribosome, nucleus localization || 1 0.00 0.34 0.33 0.56 0.29 0.54 -0.56 -0.68 0.19 0.23 -0.56 -0.41 0.12 -0.61 -0.26 -0.69
8074 || orf19.1826 || MDM34 || || Putative zinc finger transcription factor; macrophage-downregulated; flow model biofilm induced; flow model and Spider biofilm induced || 1 0.06 0.23 0.69 0.73 0.67 0.45 -1.43 -1.40 -0.06 0.20 -1.65 -0.51 -0.59 -0.71 0.16 -0.98
8075 || orf19.2444 || CHS7 || || Protein required for wild-type chitin synthase III activity; similar to (but not functional homolog of) S. cerevisiae Chs7p, which effects ER export of Chs3p; induced cyr1 mutant hyphae and ras1 yeast-form cells; Spider biofilm induced || 1 0.38 0.04 0.71 0.89 -0.23 0.11 -0.68 -0.66 -0.17 0.05 -0.69 -0.04 0.14 -0.31 0.15 -0.42
8076 || orf19.3414 || SUR7 || || Protein required for normal cell wall, plasma membrane, cytoskeletal organization, endocytosis; localizes to eisosome subdomains of plasma membrane; four transmembrane motifs; mutant shows ectopic, chitin-rich cell wall; fluconazole-induced || 1 0.29 0.10 0.56 1.03 -0.56 0.31 -1.19 -0.86 -0.44 -0.34 -0.87 -0.42 -0.25 -0.64 0.31 -0.73
8077 || orf19.1766 || || || Secreted protein; fluconazole-induced || 1 0.13 0.14 0.25 0.77 0.05 0.26 -0.60 -0.69 -0.40 0.17 -0.47 -0.41 0.03 -0.50 0.15 -0.42
8078 || orf19.5144 || PGA28 || || Protein similar to S. cerevisiae Wsc2p, which has roles in stress- and cell-wall-related processes; predicted Kex2p substrate; putative GPI-anchored adhesin-like protein || 1 0.07 0.19 1.08 1.31 0.59 0.90 -1.48 -1.68 -1.12 -0.71 -1.67 -1.17 -0.43 -1.38 0.70 -2.02
8079 || orf19.6229 || CAT1 || || Catalase; resistance to oxidative stress, neutrophils, peroxide; role in virulence; regulated by iron, ciclopirox, fluconazole, carbon source, pH, Rim101, Ssn6, Hog1, Hap43, Sfu1, Sef1, farnesol, core stress response; Spider biofilm induced || 1 0.53 0.50 1.44 1.84 0.80 0.86 -1.88 -2.07 -2.06 -0.75 -1.90 -0.62 -2.08 -3.10 0.69 -2.95
8080 || orf19.6229 || CAT1 || || Catalase; resistance to oxidative stress, neutrophils, peroxide; role in virulence; regulated by iron, ciclopirox, fluconazole, carbon source, pH, Rim101, Ssn6, Hog1, Hap43, Sfu1, Sef1, farnesol, core stress response; Spider biofilm induced || 1 0.35 0.31 1.46 1.95 0.59 0.89 -2.28 -2.37 -1.74 -0.67 -2.29 -0.54 -2.35 -3.08 0.49 -2.90
8081 || orf19.6229 || CAT1 || || Catalase; resistance to oxidative stress, neutrophils, peroxide; role in virulence; regulated by iron, ciclopirox, fluconazole, carbon source, pH, Rim101, Ssn6, Hog1, Hap43, Sfu1, Sef1, farnesol, core stress response; Spider biofilm induced || 1 0.39 0.38 1.41 1.94 0.72 0.89 -2.22 -2.35 -1.94 -0.71 -2.20 -0.59 -2.35 -3.04 0.62 -2.98
8082 || orf19.6229 || CAT1 || || Catalase; resistance to oxidative stress, neutrophils, peroxide; role in virulence; regulated by iron, ciclopirox, fluconazole, carbon source, pH, Rim101, Ssn6, Hog1, Hap43, Sfu1, Sef1, farnesol, core stress response; Spider biofilm induced || 1 0.33 0.21 1.40 1.96 0.47 0.92 -2.36 -2.37 -2.12 -0.77 -2.24 -0.69 -2.48 -3.07 0.39 -2.96
8083 || orf19.3353 || || || Protein similar to a mitochondrial complex I intermediate-associated protein; fluconazole-repressed; Spider biofilm induced; rat catheter biofilm repressed || 1 0.48 0.38 1.41 2.26 0.37 -0.17 -1.77 -1.28 -1.18 -0.95 -1.18 -1.11 -0.62 -1.99 -0.25 -1.41
8084 || orf19.3353 || || || Protein similar to a mitochondrial complex I intermediate-associated protein; fluconazole-repressed; Spider biofilm induced; rat catheter biofilm repressed || 1 0.50 0.51 1.58 2.20 0.58 0.11 -1.71 -1.47 -0.97 -0.82 -0.99 -0.57 -0.57 -1.56 -0.01 -0.97
8085 || orf19.405 || VCX1 || || Putative H+/Ca2+ antiporter; Spider biofilm repressed || 1 0.19 -0.15 0.60 0.58 0.26 0.41 -1.18 -0.72 -0.56 0.34 -0.75 -0.19 -1.01 -1.08 -0.26 -0.44
8086 || orf19.5278 || || || Protein of unknown function; Spider biofilm induced || 1 0.02 0.03 0.46 0.72 -0.46 -0.02 -0.88 -0.70 -0.40 0.16 -0.93 0.07 -1.17 -0.65 0.06 -0.19
8087 || orf19.5278 || || || Protein of unknown function; Spider biofilm induced || 1 0.15 0.21 0.35 0.58 -0.02 -0.17 -0.88 -0.63 -0.68 -0.02 -0.99 0.01 -0.72 -0.50 0.10 -0.46
8088 || orf19.4409 || || || Ortholog(s) have nucleoside-triphosphatase activity, nucleoside-triphosphate diphosphatase activity and role in cellular response to phosphate starvation, nucleoside triphosphate metabolic process || 1 0.14 -0.10 0.06 0.34 0.08 -0.16 -0.59 -0.65 -0.38 0.19 -0.97 -0.36 -0.73 -0.22 -0.06 -0.19
8089 || orf19.1494 || RAD23 || || S. cerevisiae Rad23 ortholog; binds damaged DNA; Spider biofilm repressed || 1 0.01 -0.03 0.28 0.46 0.23 -0.05 -0.47 -0.09 -0.41 0.15 -0.28 -0.14 -0.31 -0.33 -0.13 -0.24
8090 || orf19.405 || VCX1 || || Putative H+/Ca2+ antiporter; Spider biofilm repressed || 1 0.28 0.48 0.96 1.10 0.17 0.09 -1.07 -0.16 -0.53 0.40 -0.51 -0.34 -0.69 -1.30 -0.46 -1.22
8091 || orf19.5611 || || || Predicted 3-methylbutanol:NAD(P) oxidoreductase and methylglyoxal reductase (NADPH-dependent); role in ergosterol metabolic process; early stage flow model biofilm induced; Spider biofilm induced || 1 1.09 0.98 1.50 1.64 -0.56 0.53 -1.57 -1.07 -1.87 -1.06 -1.92 -1.73 -0.88 -0.85 -0.11 -0.18
8092 || orf19.5615 || AYR2 || || Putative NADPH-dependent 1-acyl dihydroxyacetone phosphate reductase; shows colony morphology-related gene regulation by Ssn6p || 1 0.45 0.36 0.40 0.90 -0.24 -0.29 -0.61 0.15 -0.40 -0.10 -1.00 -0.91 -0.50 -0.32 -1.24 -0.81
8093 || orf19.1171 || BTA1 || || Ortholog of C. dubliniensis CD36 : Cd36_10780, C. parapsilosis CDC317 : CPAR2_208080, Candida tenuis NRRL Y-1498 : CANTEDRAFT_120956 and Debaryomyces hansenii CBS767 : DEHA2F24508g || 1 2.40 2.28 2.59 2.78 -0.14 0.56 -2.97 -2.52 -2.96 -1.51 -4.57 -7.82 -1.95 -3.67 -5.30 -6.23
8094 || orf19.1171 || BTA1 || || Ortholog of C. dubliniensis CD36 : Cd36_10780, C. parapsilosis CDC317 : CPAR2_208080, Candida tenuis NRRL Y-1498 : CANTEDRAFT_120956 and Debaryomyces hansenii CBS767 : DEHA2F24508g || 1 2.16 2.16 2.58 3.16 -0.72 0.28 -3.26 -2.48 -3.11 -1.46 -6.24 -7.26 -2.32 -3.57 -6.84 -7.85
8095 || orf19.1171 || BTA1 || || Ortholog of C. dubliniensis CD36 : Cd36_10780, C. parapsilosis CDC317 : CPAR2_208080, Candida tenuis NRRL Y-1498 : CANTEDRAFT_120956 and Debaryomyces hansenii CBS767 : DEHA2F24508g || 1 1.87 1.85 2.35 3.13 -1.02 0.05 -3.82 -2.57 -3.39 -1.73 -7.60 -7.82 -2.26 -3.89 -7.55 -7.27
8096 || orf19.1171 || BTA1 || || Ortholog of C. dubliniensis CD36 : Cd36_10780, C. parapsilosis CDC317 : CPAR2_208080, Candida tenuis NRRL Y-1498 : CANTEDRAFT_120956 and Debaryomyces hansenii CBS767 : DEHA2F24508g || 1 1.56 1.69 1.98 2.69 -1.23 -0.22 -3.96 -3.23 -4.21 -2.14 -6.64 -8.43 -2.48 -4.59 -7.34 -5.99
8097 || orf19.3936 || GDE1 || || Glycerophosphocholine phosphodiesterase; mutation confers hypersensitivity to 5-fluorouracil (5-FU); F-12/CO2 early biofilm induced || 1 0.27 0.13 0.29 0.42 -0.01 0.38 -1.81 -1.20 -1.14 -0.72 -2.54 -1.98 -0.81 -0.28 -2.75 -1.66
8098 || orf19.3936 || GDE1 || || Glycerophosphocholine phosphodiesterase; mutation confers hypersensitivity to 5-fluorouracil (5-FU); F-12/CO2 early biofilm induced || 1 0.59 0.47 0.30 0.51 0.16 0.49 -1.30 -0.78 -0.79 -0.44 -2.05 -2.03 -0.43 -0.05 -2.38 -1.93
8099 || orf19.3936 || GDE1 || || Glycerophosphocholine phosphodiesterase; mutation confers hypersensitivity to 5-fluorouracil (5-FU); F-12/CO2 early biofilm induced || 1 0.70 0.53 0.56 0.68 0.26 0.77 -1.24 -0.84 -0.65 -0.42 -2.06 -1.72 -0.41 0.14 -2.16 -1.24
8100 || orf19.3936 || GDE1 || || Glycerophosphocholine phosphodiesterase; mutation confers hypersensitivity to 5-fluorouracil (5-FU); F-12/CO2 early biofilm induced || 1 0.75 0.51 0.54 0.55 0.44 0.86 -0.96 -0.75 -0.46 -0.24 -1.78 -1.34 -0.36 0.60 -1.91 -1.14
8101 || orf19.7341 || || || Protein of unknown function; flow model biofilm induced; ketoconazole-repressed || 1 0.97 0.87 0.50 0.49 0.26 0.32 -0.70 -0.42 -0.49 -0.23 -1.02 -0.74 0.17 -0.02 -0.56 -0.77
8102 || orf19.7341 || || || Protein of unknown function; flow model biofilm induced; ketoconazole-repressed || 1 0.84 0.83 1.11 0.85 0.10 0.26 -1.01 -0.59 -0.83 -0.25 -1.35 -0.74 -0.07 0.00 -1.01 -1.08
8103 || orf19.4128 || || || Ortholog of C. dubliniensis CD36 : Cd36_19390, C. parapsilosis CDC317 : CPAR2_209600, Candida tenuis NRRL Y-1498 : CANTEDRAFT_134010 and Debaryomyces hansenii CBS767 : DEHA2C14960g || 1 1.64 1.55 1.37 1.42 0.14 0.76 -1.79 -0.66 -1.01 0.19 -2.27 -1.53 -1.14 -0.06 -1.81 -1.07
8104 || orf19.4128 || || || Ortholog of C. dubliniensis CD36 : Cd36_19390, C. parapsilosis CDC317 : CPAR2_209600, Candida tenuis NRRL Y-1498 : CANTEDRAFT_134010 and Debaryomyces hansenii CBS767 : DEHA2C14960g || 1 1.42 1.57 1.32 1.59 0.12 0.67 -1.49 -0.67 -1.24 0.09 -2.09 -1.64 -1.11 -0.20 -1.79 -1.28
8105 || orf19.4128 || || || Ortholog of C. dubliniensis CD36 : Cd36_19390, C. parapsilosis CDC317 : CPAR2_209600, Candida tenuis NRRL Y-1498 : CANTEDRAFT_134010 and Debaryomyces hansenii CBS767 : DEHA2C14960g || 1 1.53 1.55 1.50 1.70 -0.03 0.34 -1.91 -0.77 -1.01 0.33 -2.14 -1.70 -0.98 -0.52 -2.10 -1.92
8106 || orf19.4128 || || || Ortholog of C. dubliniensis CD36 : Cd36_19390, C. parapsilosis CDC317 : CPAR2_209600, Candida tenuis NRRL Y-1498 : CANTEDRAFT_134010 and Debaryomyces hansenii CBS767 : DEHA2C14960g || 1 1.63 1.65 1.57 1.96 0.16 0.70 -1.53 -0.44 -0.72 0.29 -2.05 -1.52 -0.82 -0.67 -1.97 -1.39
8107 || orf19.2306 || || || Ortholog(s) have acireductone dioxygenase (Ni2+-requiring) activity, role in L-methionine salvage from methylthioadenosine and cytosol, nucleus localization || 1 1.74 1.73 1.46 1.70 0.01 0.33 -0.77 -0.59 -0.60 -0.44 -1.48 -0.97 -0.92 -0.44 -1.20 -1.28
8108 || orf19.6435 || || || Highly conserved subunit of mitochondrial pyruvate carrier; Hap43-repressed; Spider biofilm repressed || 1 1.07 1.15 1.15 1.35 0.11 -0.01 -0.56 0.04 -0.69 0.28 -1.00 -1.02 -0.40 -0.22 -0.76 -0.72
8109 || orf19.6435 || || || Highly conserved subunit of mitochondrial pyruvate carrier; Hap43-repressed; Spider biofilm repressed || 1 1.24 1.19 1.20 1.48 0.02 -0.20 -0.83 -0.08 -0.70 0.03 -1.25 -1.58 -0.47 -0.98 -1.43 -1.53
8110 || orf19.1224 || FRP3 || || Putative ammonium transporter; upregulated in the presence of human neutrophils; fluconazole-downregulated; repressed by nitric oxide; Spider biofilm induced; rat catheter biofilm repressed || 1 1.47 1.49 2.01 1.80 0.35 0.15 -1.51 -1.16 -1.66 -0.15 -1.91 -1.24 -0.74 -1.68 -0.80 -1.66
8111 || orf19.6707 || || || Predicted vacuolar protein with a calcineurin-like phosphoesterase domain; repressed by alpha pheromone in SpiderM medium || 1 0.63 0.65 0.64 0.69 -0.16 0.35 -0.41 -0.27 -0.12 -0.05 -0.58 -0.82 -0.27 -0.78 -0.56 -0.64
8112 || orf19.6707 || || || Predicted vacuolar protein with a calcineurin-like phosphoesterase domain; repressed by alpha pheromone in SpiderM medium || 1 0.83 0.72 0.57 0.52 -0.83 -0.33 -0.27 0.01 -0.12 0.22 -1.28 -1.61 -0.69 -0.68 -0.87 -1.17
8113 || orf19.3432 || || || Predicted membrane transporter, member of the drug:proton antiporter (12 spanner) (DHA1) family, major facilitator superfamily (MFS); induced by nitric oxide || 1 1.24 1.22 1.29 1.76 -1.17 -0.74 -0.54 -0.84 0.77 -0.93 -1.64 -1.42 -1.42 -0.12 -1.57 -2.01
8114 || orf19.3870 || ADE13 || || Adenylosuccinate lyase; enzyme of adenine biosynthesis; soluble protein in hyphae; not induced during GCN response, in contrast to the S. cerevisiae ortholog; repressed by nitric oxide || 1 0.94 0.92 0.77 0.70 -0.62 -0.50 -0.39 -0.05 0.11 -0.36 -1.82 -1.23 -1.04 0.01 -1.84 -1.41
8115 || orf19.3870 || ADE13 || || Adenylosuccinate lyase; enzyme of adenine biosynthesis; soluble protein in hyphae; not induced during GCN response, in contrast to the S. cerevisiae ortholog; repressed by nitric oxide || 1 0.99 0.90 0.81 0.67 -0.44 -0.10 -0.58 -0.26 0.13 -0.42 -1.70 -0.85 -1.10 0.29 -1.48 -1.10
8116 || orf19.2306 || || || Ortholog(s) have acireductone dioxygenase (Ni2+-requiring) activity, role in L-methionine salvage from methylthioadenosine and cytosol, nucleus localization || 1 1.50 1.52 1.06 0.81 -0.28 -0.12 -0.78 -0.64 -0.58 -0.72 -1.44 -1.56 -0.95 -0.57 -1.14 -1.35
8117 || orf19.6586 || || || Protein of unknown function; transcript induced by benomyl or in azole-resistant strain overexpressing MDR1; Ssn6 colony morphology-related regulation; induced by NO; Hap43-repressed; rat catheter and flow model biofilm induced || 1 2.39 2.31 2.81 2.10 -1.26 -0.22 -0.85 -1.39 -0.27 0.14 -2.44 -3.37 -2.45 -1.43 -2.57 -3.60
8118 || orf19.6586 || || || Protein of unknown function; transcript induced by benomyl or in azole-resistant strain overexpressing MDR1; Ssn6 colony morphology-related regulation; induced by NO; Hap43-repressed; rat catheter and flow model biofilm induced || 1 1.92 1.98 2.32 1.74 -1.21 -0.53 -1.11 -1.52 -0.51 -0.02 -2.58 -3.36 -2.66 -1.74 -2.68 -3.51
8119 || orf19.4445 || || || Protein of unknown function; Plc1p-regulated; expression induced early upon infection of reconstituted human epithelium (RHE), while expression of the C. dubliniensis ortholog is not; mutant is viable; Spider biofilm induced || 1 1.46 1.33 1.24 1.69 -0.31 -0.19 -0.58 -1.86 -0.81 -0.37 -2.56 -3.57 -1.90 -0.09 -1.96 -2.46
8120 || orf19.4445 || || || Protein of unknown function; Plc1p-regulated; expression induced early upon infection of reconstituted human epithelium (RHE), while expression of the C. dubliniensis ortholog is not; mutant is viable; Spider biofilm induced || 1 1.49 1.48 1.03 1.57 -0.35 -0.03 -0.46 -1.79 -0.75 -0.05 -2.73 -2.88 -1.93 0.07 -1.78 -2.98
8121 || orf19.4445 || || || Protein of unknown function; Plc1p-regulated; expression induced early upon infection of reconstituted human epithelium (RHE), while expression of the C. dubliniensis ortholog is not; mutant is viable; Spider biofilm induced || 1 1.54 1.61 1.24 1.55 -0.18 0.14 -0.30 -1.60 -0.73 -0.11 -2.49 -2.86 -1.79 0.21 -1.46 -2.34
8122 || orf19.4445 || || || Protein of unknown function; Plc1p-regulated; expression induced early upon infection of reconstituted human epithelium (RHE), while expression of the C. dubliniensis ortholog is not; mutant is viable; Spider biofilm induced || 1 1.53 1.55 1.32 1.67 -0.16 0.11 -0.30 -1.51 -0.63 -0.08 -2.28 -2.59 -1.78 0.34 -1.47 -2.13
8123 || orf19.4445 || || || Protein of unknown function; Plc1p-regulated; expression induced early upon infection of reconstituted human epithelium (RHE), while expression of the C. dubliniensis ortholog is not; mutant is viable; Spider biofilm induced || 1 1.76 1.84 1.69 2.11 0.23 0.27 0.05 -1.05 -0.28 0.26 -1.95 -2.59 -1.34 0.17 -1.11 -2.11
8124 || orf19.3355 || ISN1 || || Putative inosine 5'-monophosphate 5'-nucleotidase; fungal-specific (no human or murine homolog) || 1 0.70 0.83 0.75 0.64 -0.19 0.14 -0.64 -0.38 -0.11 -0.68 -0.94 -0.61 -0.70 0.17 -0.65
8125 || orf19.3810 || || || Ortholog(s) have methylenetetrahydrofolate dehydrogenase (NAD+) activity, role in folic acid-containing compound biosynthetic process, one-carbon metabolic process, purine nucleobase biosynthetic process and cytosol, nucleus localization || 1 1.11 1.10 0.92 0.78 -0.10 0.22 -1.22 -0.96 -0.18 -0.83 -1.85 -1.14 -0.88 -0.19 -1.04 -1.69
8126 || orf19.3810 || || || Ortholog(s) have methylenetetrahydrofolate dehydrogenase (NAD+) activity, role in folic acid-containing compound biosynthetic process, one-carbon metabolic process, purine nucleobase biosynthetic process and cytosol, nucleus localization || 1 0.77 0.58 0.88 0.58 -0.55 -0.03 -1.52 -1.37 -0.20 -0.63 -2.24 -1.27 -1.53 -0.47 -1.28 -1.51
8127 || orf19.6869 || || || Putative lipid raft associated protein; Spider biofilm induced || 1 0.69 0.68 1.30 0.57 0.15 0.49 -1.43 -1.61 -0.69 -0.89 -3.06 -1.71 -1.69 -0.91 -0.93 -1.76
8128 || orf19.6869 || || || Putative lipid raft associated protein; Spider biofilm induced || 1 0.91 0.89 1.60 0.89 0.33 0.66 -1.05 -1.38 -0.34 -0.75 -2.82 -1.31 -1.52 -0.61 -0.65 -1.44
8129 || orf19.6869 || || || Putative lipid raft associated protein; Spider biofilm induced || 1 0.99 0.94 1.66 1.02 0.52 0.78 -0.62 -1.02 -0.28 -0.45 -1.74 -0.97 -0.73 -0.38 -0.29 -0.90
8130 || orf19.6869 || || || Putative lipid raft associated protein; Spider biofilm induced || 1 1.36 1.26 1.62 1.03 0.80 0.72 -1.10 -1.24 -0.06 -0.54 -2.72 -1.43 -1.10 -0.67 -0.74 -1.55
8131 || orf19.670.2 || || || Protein of unknown function; hypoxia, Hap43-repressed; ketoconazole induced; induced in oralpharyngeal candidasis; 16h flow model biofilm repressed, late-stage flow model biofilm induced; rat catheter and Spider biofilm induced || 1 2.14 2.04 2.20 1.41 0.27 0.13 -1.25 -1.75 0.48 -0.74 -4.46 -1.70 -1.03 -0.70 -0.99 -2.13
8132 || orf19.670.2 || || || Protein of unknown function; hypoxia, Hap43-repressed; ketoconazole induced; induced in oralpharyngeal candidasis; 16h flow model biofilm repressed, late-stage flow model biofilm induced; rat catheter and Spider biofilm induced || 1 2.31 2.28 2.32 1.88 0.32 0.19 -1.33 -1.91 0.39 -0.89 -4.61 -1.37 -1.18 -0.22 -0.89 -1.65
8133 || orf19.996 || || || Protein with a predicted leucine-rich repeat domain; possibly an essential gene, disruptants not obtained by UAU1 method || 1 0.58 0.35 1.25 1.26 0.36 0.77 -1.03 -0.90 0.35 -0.03 -1.70 -0.87 -0.91 -0.45 -0.68 -1.70
8134 || orf19.5940 || ZCF32 || || Predicted Zn(II)2Cys6 transcription factor; possibly an essential gene, disruptants not obtained by UAU1 method; Hap43-repressed || 1 0.21 0.11 0.46 0.78 0.08 0.14 -0.54 -0.30 -0.32 -0.66 -0.81 -0.49 -0.15 -0.25 -0.35 -0.50
8135 || orf19.4917 || || || Ortholog of Candida albicans WO-1 : CAWG_00155 || 1 0.09 -0.13 0.54 0.69 -0.11 -0.05 -1.12 -0.78 -0.76 -1.21 -1.10 -0.94 -0.89 -0.45 -0.64 -0.19
8136 || orf19.2836 || || || Protein with similarity to carbonic anhydrases || 1 0.78 0.57 1.53 2.08 -0.68 0.03 -2.17 -1.57 -1.42 -1.85 -2.76 -1.48 -2.02 -0.96 -0.63 -1.03
8137 || orf19.7495 || || || Protein with NADPH oxidoreductase containing flavin mononucleotide (FMN) domain; induced by nitric oxide || 1 0.06 0.12 0.75 0.85 -0.35 -0.23 -0.72 -0.42 -0.32 -0.82 -0.83 -0.75 0.06 -0.50 -0.56 -0.86
8138 || orf19.690 || PLB2 || || Putative phospholipase B; conserved catalytic region; 6 putative N-glycosylation motifs; predicted secretion signal; no GPI anchor predicted; fungal-specific (no human or murine homolog) || 1 0.07 -0.16 0.83 0.85 -0.55 -0.28 -1.10 -0.93 -0.73 -0.72 -1.19 -0.74 -0.26 -0.59 -0.79 -1.21
8139 || orf19.5022 || || || Ortholog(s) have inorganic cation transmembrane transporter activity and role in cellular cobalt ion homeostasis, cellular manganese ion homeostasis, cobalt ion transport, manganese ion transport || 1 -0.05 0.13 0.43 0.47 -0.15 0.08 -0.52 -0.51 -0.73 -0.41 -0.64 -0.59 -0.10 -0.14 -0.30 -0.33
8140 || orf19.1449 || || || Protein of unknown function; induced in azole-resistant strain that overexpresses MDR1; protein present in exponential and stationary growth phase yeast cultures; Spider biofilm induced || 1 0.09 0.08 0.54 0.61 -0.34 0.04 -0.65 -0.92 -0.65 -0.68 -1.12 -0.81 -0.34 -0.18 -0.59 -0.48
8141 || orf19.4482 || IFI3 || || Protein of unknown function; constitutive expression independent of MTL or white-opaque status || 1 0.25 0.28 1.00 0.80 -0.67 -0.23 -0.40 -1.00 -0.90 -1.19 -1.88 -1.31 -0.38 -0.31 -1.13 -0.73
8142 || orf19.2552 || || || Protein similar to S. cerevisiae Pmr1p; amphotericin B induced; previously merged with orf19.2553; unmerged from orf19.2553 in a revision of Assembly 21 || 1 1.03 1.35 2.28 2.38 -3.12 -2.69 -3.35 -3.27 -2.37 -2.72 -3.68 -1.73 -2.77 -1.85 -3.16 -1.39
8143 || orf19.5124 || RBR3 || || Cell wall adhesin-like protein; repressed by Rim101; possibly an essential gene, disruptants not obtained by UAU1 method || 1 0.78 0.65 1.99 1.45 -0.85 -0.35 -2.03 -2.24 -1.64 -2.24 -2.06 -1.20 -1.34 -1.62 -1.33 -1.06
8144 || orf19.5124 || RBR3 || || Cell wall adhesin-like protein; repressed by Rim101; possibly an essential gene, disruptants not obtained by UAU1 method || 1 0.57 0.49 1.90 1.24 -1.01 -0.61 -2.61 -2.66 -2.32 -2.67 -2.20 -1.65 -1.68 -2.24 -1.68 -1.14
8145 || orf19.6249 || HAK1 || || Putative potassium transporter; similar to Schwanniomyces occidentalis Hak1p; amphotericin B induced; induced upon phagocytosis by macrophage; Hap43-repressed; rat catheter biofilm repressed || 1 1.42 1.47 2.34 2.78 -1.45 -2.75 -3.53 -4.40 -4.61 -5.00 -5.15 -4.17 -3.59 -2.47 -3.84 -2.87
8146 || orf19.6249 || HAK1 || || Putative potassium transporter; similar to Schwanniomyces occidentalis Hak1p; amphotericin B induced; induced upon phagocytosis by macrophage; Hap43-repressed; rat catheter biofilm repressed || 1 1.45 1.49 2.05 2.62 -1.51 -3.34 -3.97 -5.23 -5.13 -4.93 -5.57 -4.46 -3.71 -3.38 -3.88 -3.02
8147 || orf19.6249 || HAK1 || || Putative potassium transporter; similar to Schwanniomyces occidentalis Hak1p; amphotericin B induced; induced upon phagocytosis by macrophage; Hap43-repressed; rat catheter biofilm repressed || 1 1.51 1.46 2.44 2.74 -1.57 -3.25 -3.82 -4.99 -4.32 -4.76 -4.90 -4.67 -3.96 -3.23 -4.06 -2.67
8148 || orf19.6249 || HAK1 || || Putative potassium transporter; similar to Schwanniomyces occidentalis Hak1p; amphotericin B induced; induced upon phagocytosis by macrophage; Hap43-repressed; rat catheter biofilm repressed || 1 0.86 1.00 1.99 2.65 -1.31 -2.83 -2.19 -3.39 -4.08 -4.25 -2.83 -3.72 -1.72 -2.97 -2.65 -2.24
8149 || orf19.6249 || HAK1 || || Putative potassium transporter; similar to Schwanniomyces occidentalis Hak1p; amphotericin B induced; induced upon phagocytosis by macrophage; Hap43-repressed; rat catheter biofilm repressed || 1 1.93 2.01 2.77 2.93 -0.93 -2.64 -1.84 -2.37 -3.01 -3.83 -2.89 -3.24 -2.35 -2.31 -2.58 -2.20
8150 || orf19.7597 || PGA12 || || Putative GPI-anchored protein || 1 1.69 1.59 2.58 2.79 -1.98 -2.71 -1.83 -2.07 -2.35 -3.41 -3.38 -3.44 -1.88 -3.10 -2.45 -2.63
8151 || orf19.5592 || || || Ortholog of C. dubliniensis CD36 : Cd36_63980, Candida tenuis NRRL Y-1498 : CANTEDRAFT_115187, Candida tropicalis MYA-3404 : CTRG_02719 and Candida albicans WO-1 : CAWG_05060 || 1 1.34 1.39 2.44 2.19 -1.19 0.15 -1.52 -1.81 -1.76 -2.36 -1.63 -1.21 -1.65 -2.92 -1.75 -2.95
8152 || orf19.1980 || GIT4 || || Glycerophosphocholine transporter; fungal-specific (no human or murine homolog); possibly an essential gene, disruptants not obtained by UAU1 method; Hap43p-repressed gene || 1 1.45 1.53 2.30 2.14 -0.47 0.04 -0.93 -1.71 -0.57 -2.09 -1.96 -2.44 -0.27 -0.73 -2.12 -1.79
8153 || orf19.1980 || GIT4 || || Glycerophosphocholine transporter; fungal-specific (no human or murine homolog); possibly an essential gene, disruptants not obtained by UAU1 method; Hap43p-repressed gene || 1 1.53 1.36 2.13 2.17 -1.07 -0.32 -1.47 -1.93 -1.04 -2.19 -2.33 -2.62 -0.87 -0.85 -2.40 -1.93
8154 || orf19.984 || PHO8 || || Putative repressible vacuolar alkaline phosphatase; Rim101-induced transcript; regulated by Tsa1, Tsa1B in minimal media at 37 deg; possibly adherence-induced || 1 1.20 1.21 1.86 1.93 -2.96 -0.29 -2.55 -2.98 -1.77 -2.20 -3.89 -3.31 -2.97 -0.98 -4.00 -2.36
8155 || orf19.984 || PHO8 || || Putative repressible vacuolar alkaline phosphatase; Rim101-induced transcript; regulated by Tsa1, Tsa1B in minimal media at 37 deg; possibly adherence-induced || 1 1.21 1.38 1.94 2.31 -2.55 -0.15 -2.62 -2.63 -1.70 -1.78 -3.76 -1.89 -2.34 -1.76 -3.51 -1.12
8156 || orf19.6023 || || || Protein with a predicted multidrug transporter domain; Hap43-repressed gene || 1 0.55 0.61 0.99 1.47 -1.58 -0.60 -1.33 -1.50 -0.81 -0.86 -2.18 -0.81 -1.10 -0.72 -2.08 -0.74
8157 || orf19.1042 || POR1 || || Mitochondrial outer membrane porin; in detergent-resistant membrane fraction (possible lipid raft component); antigenic in human, mouse; Hap43p-induced; flucytosine-, macrophage-, farnesol- induced; fluconazole, caspofungin repressed || 1 0.48 0.44 0.76 0.97 -0.23 -0.08 -0.92 -0.81 -0.30 -0.54 -1.01 -0.76 -0.58 -0.44 -1.23 -0.39
8158 || orf19.6826 || SLF1 || || Putative polysome-associated RNA binding protein; macrophage-induced gene || 1 1.40 1.51 1.92 2.12 -0.94 0.26 -3.36 -2.59 -0.92 -1.05 -3.77 -2.19 -2.07 -1.51 -3.40 -2.40
8159 || orf19.6037 || ASM3 || || Putative secreted acid sphingomyelin phosphodiesterase; possible Kex2 substrate; transcript increased in an azole-resistant strain that overexpresses MDR1; flow model biofilm induced; F-12/CO2 early biofilm induced || 1 1.80 1.79 2.42 2.35 -1.56 -0.09 -3.27 -3.88 -2.78 -3.40 -4.36 -3.24 -3.16 -2.75 -4.06 -2.78
8160 || orf19.6037 || ASM3 || || Putative secreted acid sphingomyelin phosphodiesterase; possible Kex2 substrate; transcript increased in an azole-resistant strain that overexpresses MDR1; flow model biofilm induced; F-12/CO2 early biofilm induced || 1 1.87 1.85 2.56 2.56 -1.37 0.02 -3.10 -3.54 -2.18 -3.10 -3.94 -3.13 -2.80 -2.79 -3.68 -2.28
8161 || orf19.984 || PHO8 || || Putative repressible vacuolar alkaline phosphatase; Rim101-induced transcript; regulated by Tsa1, Tsa1B in minimal media at 37 deg; possibly adherence-induced || 1 0.98 0.95 1.95 2.07 -1.09 -0.11 -1.96 -1.85 -1.16 -1.32 -2.26 -1.60 -1.45 -1.08 -1.90 -1.96
8162 || orf19.5925 || || || Ortholog of S. cerevisiae : AIM6, C. glabrata CBS138 : CAGL0C05533g, C. dubliniensis CD36 : Cd36_84610, C. parapsilosis CDC317 : CPAR2_404550 and Candida tenuis NRRL Y-1498 : CANTEDRAFT_115337 || 1 1.26 1.22 1.42 1.95 -0.79 0.30 -1.66 -2.14 -1.23 -1.13 -2.58 -1.56 -1.60 -1.40 -1.42 -2.28
8163 || orf19.5925 || || || Ortholog of S. cerevisiae : AIM6, C. glabrata CBS138 : CAGL0C05533g, C. dubliniensis CD36 : Cd36_84610, C. parapsilosis CDC317 : CPAR2_404550 and Candida tenuis NRRL Y-1498 : CANTEDRAFT_115337 || 1 1.43 1.56 1.99 2.05 -0.60 0.28 -1.58 -1.68 -1.21 -1.17 -2.55 -1.44 -1.39 -1.47 -1.61 -2.08
8164 || orf19.5592 || || || Ortholog of C. dubliniensis CD36 : Cd36_63980, Candida tenuis NRRL Y-1498 : CANTEDRAFT_115187, Candida tropicalis MYA-3404 : CTRG_02719 and Candida albicans WO-1 : CAWG_05060 || 1 0.75 1.00 2.14 1.97 -0.60 0.07 -1.23 -1.44 -1.06 -1.78 -2.04 -1.74 -0.86 -2.19 -1.27 -1.54
8165 || orf19.5826 || || || Predicted amino acid transmembrane transporter; rat catheter biofilm repressed || 1 1.09 1.08 2.20 2.13 -1.61 -1.01 -1.34 -1.26 -0.48 -1.59 -3.18 -2.03 -0.94 -2.30 -1.81 -2.51
8166 || orf19.5826 || || || Predicted amino acid transmembrane transporter; rat catheter biofilm repressed || 1 1.28 1.24 1.95 2.18 -1.21 -1.31 -1.27 -1.17 -0.76 -1.63 -2.44 -2.02 -0.62 -1.96 -1.51 -1.73
8167 || orf19.1005 || || || Protein with predicted RNI-like domains; rat catheter biofilm induced || 1 1.32 1.42 2.13 2.03 -1.11 -0.69 -1.31 -1.65 -0.57 -1.42 -2.35 -1.83 -0.32 -1.45 -1.67 -1.90
8168 || orf19.1005 || || || Protein with predicted RNI-like domains; rat catheter biofilm induced || 1 1.78 1.87 2.60 2.38 -1.86 -0.79 -1.41 -2.19 -1.11 -1.12 -2.69 -1.77 -0.72 -1.33 -1.97 -1.47
8169 || orf19.984 || PHO8 || || Putative repressible vacuolar alkaline phosphatase; Rim101-induced transcript; regulated by Tsa1, Tsa1B in minimal media at 37 deg; possibly adherence-induced || 1 1.01 1.30 1.92 2.26 -1.96 -0.41 -1.54 -1.48 -1.18 -1.34 -2.66 -1.62 -1.34 -1.49 -2.19 -1.80
8170 || orf19.2164.1 || MFA1 || || a-factor mating pheromone; produced in opaque MTLa cells; required for mating competence of MTLa cells, but not MTLalpha; induced by alpha-factor || 1 1.88 1.89 2.75 2.80 -1.90 -0.32 -2.15 -1.70 -2.44 -1.15 -2.39 -1.58 -1.87 -1.98 -2.52
8171 || orf19.2164.1 || MFA1 || || a-factor mating pheromone; produced in opaque MTLa cells; required for mating competence of MTLa cells, but not MTLalpha; induced by alpha-factor || 1 2.04 1.94 2.98 3.04 -1.20 0.01 -2.24 -1.87 -2.26 -0.56 -2.82 -1.55 -1.74 -2.75 -2.26 -2.20
8172 || orf19.2164.1 || MFA1 || || a-factor mating pheromone; produced in opaque MTLa cells; required for mating competence of MTLa cells, but not MTLalpha; induced by alpha-factor || 1 2.14 1.87 3.08 2.93 -1.27 -0.06 -2.23 -2.07 -2.20 -0.80 -2.56 -2.39 -1.56 -3.09 -2.38 -2.34
8173 || orf19.2164.1 || MFA1 || || a-factor mating pheromone; produced in opaque MTLa cells; required for mating competence of MTLa cells, but not MTLalpha; induced by alpha-factor || 1 1.79 2.06 3.13 3.03 -2.48 -0.47 -2.49 -2.04 -2.37 -0.72 -3.45 -3.38 -1.86 -3.57 -2.40 -2.47
8174 || orf19.2164.1 || MFA1 || || a-factor mating pheromone; produced in opaque MTLa cells; required for mating competence of MTLa cells, but not MTLalpha; induced by alpha-factor || 1 2.02 1.62 3.02 3.04 -1.83 -0.79 -1.94 -1.89 -1.88 -1.07 -2.17 -3.15 -1.10 -2.57 -1.83
8175 || orf19.2652 || TEF4 || || Putative translation elongation factor; genes encoding ribosomal subunits, translation factors, and tRNA synthetases are downregulated upon phagocytosis by murine macrophage || 1 1.82 1.86 2.74 3.00 -1.09 -0.26 -2.24 -1.61 -0.83 -0.95 -2.11 -2.11 -1.29 -1.71 -1.08 -2.69
8176 || orf19.2652 || TEF4 || || Putative translation elongation factor; genes encoding ribosomal subunits, translation factors, and tRNA synthetases are downregulated upon phagocytosis by murine macrophage || 1 2.02 1.94 2.43 2.74 -1.47 0.13 -1.88 -1.35 -1.38 -1.13 -2.10 -2.82 -1.52 -0.99 -2.29 -1.65
8177 || orf19.7661 || HMI1 || || ATP-dependent 3' - 5' helicase involved in maintenance of mitochondrial DNA; ortholog of S. cerevisiae Hmi1; rat catheter biofilm repressed || 1 0.61 0.49 1.01 1.01 -0.65 -0.13 -0.57 -0.68 -0.08 -0.58 -1.12 -0.65 -0.79 -0.54 -0.53 -0.18
8178 || orf19.7661 || HMI1 || || ATP-dependent 3' - 5' helicase involved in maintenance of mitochondrial DNA; ortholog of S. cerevisiae Hmi1; rat catheter biofilm repressed || 1 0.56 0.37 0.75 0.80 -0.72 -0.25 -0.61 -0.84 -0.30 -0.81 -1.13 -0.72 -0.61 -0.46 -0.62 -0.26
8179 || orf19.1639 || || || Has domain(s) with predicted oxidoreductase activity and role in oxidation-reduction process || 1 0.25 0.54 0.78 1.09 -0.66 -0.26 -0.72 -0.94 -0.06 -1.01 -1.36 -0.70 -0.65 -0.41 -0.54 -0.69
8180 || orf19.984 || PHO8 || || Putative repressible vacuolar alkaline phosphatase; Rim101-induced transcript; regulated by Tsa1, Tsa1B in minimal media at 37 deg; possibly adherence-induced || 1 1.28 1.24 1.79 2.07 -1.23 0.83 -1.43 -1.71 -0.47 -0.86 -1.64 -1.03 -1.70 -0.20 -1.45 -0.45
8181 || orf19.2652 || TEF4 || || Putative translation elongation factor; genes encoding ribosomal subunits, translation factors, and tRNA synthetases are downregulated upon phagocytosis by murine macrophage || 1 2.01 1.80 2.40 2.75 -1.03 -0.10 -2.41 -2.14 -0.99 -0.70 -1.78 -1.61 -1.61 -1.30 -1.92 -0.55
8182 || orf19.2652 || TEF4 || || Putative translation elongation factor; genes encoding ribosomal subunits, translation factors, and tRNA synthetases are downregulated upon phagocytosis by murine macrophage || 1 1.98 1.94 2.78 3.01 -1.25 0.18 -1.79 -1.87 -1.40 -0.69 -2.58 -0.83 -2.02 -1.10 -1.83 -1.77
8183 || orf19.2652 || TEF4 || || Putative translation elongation factor; genes encoding ribosomal subunits, translation factors, and tRNA synthetases are downregulated upon phagocytosis by murine macrophage || 1 1.32 1.23 2.33 2.43 -0.79 0.27 -1.39 -1.51 -1.01 -0.94 -1.10 -1.97 -1.85 -1.66 -1.79 -1.25
8184 || orf19.3352 || || || Has domain(s) with predicted oxidoreductase activity and role in metabolic process || 1 1.25 1.39 2.14 2.38 -0.27 -0.79 -1.23 -1.24 -1.33 -0.28 -1.95 -1.33 -1.02 -0.60 -1.55 -1.20
8185 || orf19.3352 || || || Has domain(s) with predicted oxidoreductase activity and role in metabolic process || 1 1.18 1.24 1.62 1.92 -0.23 -0.77 -1.33 -1.29 -1.49 -0.22 -2.45 -1.64 -1.10 -0.48 -1.57 -1.53
8186 || orf19.4355 || || || Ortholog of C. dubliniensis CD36 : Cd36_29080, C. parapsilosis CDC317 : CPAR2_202490, Candida tenuis NRRL Y-1498 : CANTEDRAFT_112323 and Debaryomyces hansenii CBS767 : DEHA2F19184g || 1 2.27 2.21 2.19 2.60 -1.13 -1.20 -1.97 -2.16 -2.44 -2.18 -3.53 -3.54 -2.40 -2.92 -3.48 -4.28
8187 || orf19.1171 || BTA1 || || Ortholog of C. dubliniensis CD36 : Cd36_10780, C. parapsilosis CDC317 : CPAR2_208080, Candida tenuis NRRL Y-1498 : CANTEDRAFT_120956 and Debaryomyces hansenii CBS767 : DEHA2F24508g || 1 2.24 2.01 2.56 3.32 -0.71 0.26 -2.05 -2.11 -2.60 -1.83 -3.66 -4.57 -1.78 -3.74 -3.19 -4.58
8188 || orf19.2619 || PHO113 || || Putative constitutive acid phosphatase; Rim101-repressed; DTT-extractable; N-glycosylated; possibly an essential gene, disruptants not obtained by UAU1 method || 1 2.00 1.85 -0.88 0.25 -3.93 -3.64 -3.53 -2.90 -4.79 -5.26 -2.32 -3.50 -3.72 -4.62
8189 || orf19.3727 || PHO112 || || Putative constitutive acid phosphatase; Rim101-repressed; DTT-extractable; N-glycosylated; Hap43-induced; possibly an essential gene, disruptants not obtained by UAU1 method || 1 2.20 2.32 2.58 2.56 -0.22 0.40 -3.42 -3.41 -3.37 -2.71 -4.57 -4.75 -1.84 -4.02 -3.82 -5.55
8190 || orf19.3727 || PHO112 || || Putative constitutive acid phosphatase; Rim101-repressed; DTT-extractable; N-glycosylated; Hap43-induced; possibly an essential gene, disruptants not obtained by UAU1 method || 1 2.32 2.09 2.67 3.11 -0.51 0.14 -3.17 -3.08 -3.99 -3.18 -4.20 -5.15 -1.95 -4.43 -3.12 -4.77
8191 || orf19.2619 || PHO113 || || Putative constitutive acid phosphatase; Rim101-repressed; DTT-extractable; N-glycosylated; possibly an essential gene, disruptants not obtained by UAU1 method || 1 2.54 2.18 2.75 2.74 -0.32 0.52 -3.10 -3.23 -3.82 -3.43 -3.51 -4.60 -1.50 -3.58 -2.86 -3.74
8192 || orf19.6826 || SLF1 || || Putative polysome-associated RNA binding protein; macrophage-induced gene || 1 1.44 1.60 2.13 2.59 -0.12 0.56 -2.08 -2.53 -1.18 -1.29 -3.06 -3.03 -0.41 -2.53 -2.26 -2.01
8193 || orf19.6826 || SLF1 || || Putative polysome-associated RNA binding protein; macrophage-induced gene || 1 2.13 2.20 2.47 2.65 -0.71 0.24 -3.15 -3.42 -1.56 -1.67 -4.29 -4.19 -1.21 -4.85 -4.25 -4.30
8194 || orf19.6826 || SLF1 || || Putative polysome-associated RNA binding protein; macrophage-induced gene || 1 1.96 2.03 2.22 2.48 -0.65 0.26 -3.30 -3.66 -1.65 -1.77 -4.35 -4.80 -1.23 -5.91 -3.83 -3.76
8195 || orf19.4873 || || || Protein of unknown function; transcript regulated by white-opaque switch; flow model biofilm induced; Spider biofilm induced || 1 1.76 1.58 2.91 2.70 -0.87 0.26 -3.23 -3.89 -2.51 -2.33 -4.65 -3.36 -0.81 -3.08 -1.57 -3.89
8196 || orf19.4873 || || || Protein of unknown function; transcript regulated by white-opaque switch; flow model biofilm induced; Spider biofilm induced || 1 2.21 2.01 2.84 2.81 -0.49 0.22 -3.26 -4.24 -2.96 -3.87 -5.41 -4.16 -0.54 -3.18 -1.17 -4.38
8197 || orf19.4873 || || || Protein of unknown function; transcript regulated by white-opaque switch; flow model biofilm induced; Spider biofilm induced || 1 1.88 1.73 2.51 2.52 -0.84 0.35 -3.17 -3.94 -2.61 -4.00 -4.58 -3.87 -0.99 -2.71 -1.21 -3.23
8198 || orf19.4873 || || || Protein of unknown function; transcript regulated by white-opaque switch; flow model biofilm induced; Spider biofilm induced || 1 1.68 1.66 2.55 2.45 -0.90 0.21 -3.46 -4.44 -2.91 -4.12 -5.07 -4.22 -1.01 -3.28 -1.43 -3.90
8199 || orf19.4873 || || || Protein of unknown function; transcript regulated by white-opaque switch; flow model biofilm induced; Spider biofilm induced || 1 1.59 1.47 2.50 2.28 -1.16 0.08 -3.13 -4.00 -2.79 -3.48 -4.93 -3.72 -0.90 -2.64 -1.41 -3.08
8200 || orf19.7596 || || || Protein with a phosphoglycerate mutase family domain; Hap43-repressed gene || 1 1.72 1.68 2.46 2.21 0.35 1.20 -4.40 -4.29 -3.23 -3.90 -5.47 -4.45 0.21 -2.35 -3.48 -4.13
8201 || orf19.7596 || || || Protein with a phosphoglycerate mutase family domain; Hap43-repressed gene || 1 1.91 1.81 2.41 2.37 0.35 1.35 -2.83 -3.09 -2.70 -3.57 -3.54 -3.97 0.26 -2.55 -2.65 -3.03
8202 || orf19.258 || || || Protein of unknown function; Spider biofilm induced || 1 1.27 1.22 1.35 1.41 -0.25 0.55 -1.54 -0.98 -0.64 -1.86 -1.91 -1.24 -0.87 -1.18 -1.54 -0.87
8203 || orf19.34 || GIT1 || || Glycerophosphoinositol permease; involved in utilization of glycerophosphoinositol as a phosphate source; Rim101-repressed; virulence-group-correlated expression || 1 1.39 1.17 1.63 1.69 0.74 2.10 -1.34 -1.59 -0.87 -2.34 -1.53 -2.11 -0.83 -2.35 -1.60 -1.01
8204 || orf19.34 || GIT1 || || Glycerophosphoinositol permease; involved in utilization of glycerophosphoinositol as a phosphate source; Rim101-repressed; virulence-group-correlated expression || 1 1.32 1.10 1.59 1.61 0.49 1.94 -1.43 -2.20 -1.68 -2.63 -2.67 -2.46 -1.38 -2.40 -1.81 -2.38
8205 || orf19.5925 || || || Ortholog of S. cerevisiae : AIM6, C. glabrata CBS138 : CAGL0C05533g, C. dubliniensis CD36 : Cd36_84610, C. parapsilosis CDC317 : CPAR2_404550 and Candida tenuis NRRL Y-1498 : CANTEDRAFT_115337 || 1 1.06 0.94 1.28 1.47 0.23 0.43 -1.45 -1.64 -0.93 -0.87 -1.36 -1.16 -1.53 -1.08 -0.93 -1.24
8206 || orf19.3200 || MTLA2 || || Master regulator (activator) of a-type mating; has HMG domain, which is predicted to bind DNA; gene has intron; not related to S. cerevisiae MATa2; a/alpha mating type may increase virulence, provides competitive advantage || 1 1.49 1.39 1.45 1.46 0.53 0.79 -1.27 -1.35 -1.33 -1.11 -1.64 -1.48 -0.95 -0.94 -1.11 -1.28
8207 || orf19.3200 || MTLA2 || || Master regulator (activator) of a-type mating; has HMG domain, which is predicted to bind DNA; gene has intron; not related to S. cerevisiae MATa2; a/alpha mating type may increase virulence, provides competitive advantage || 1 1.35 1.27 1.01 1.17 0.41 0.60 -1.47 -1.29 -1.49 -1.31 -1.36 -1.16 -1.05 -1.53 -1.27 -1.54
8208 || orf19.1527 || || || Protein of unknown function; Spider biofilm induced || 1 0.84 0.81 1.34 1.14 0.41 0.63 -0.59 -0.84 -0.96 -0.91 -0.89 -0.80 -0.37 -0.65 -0.31 -0.84
8209 || orf19.4371 || TAL1 || || Transaldolase; protein present in exponential and stationary growth phase yeast cultures; oxidative stress-induced via Cap1; induced by nitric oxide independent of Yhb1p; sumoylation target; rat catheter biofilm repressed || 1 0.88 0.83 0.81 0.84 -0.57 -0.43 -0.79 -0.85 -0.61 -0.73 -0.75 -0.45 -0.18 -0.34 -0.34 -0.47
8210 || orf19.4371 || TAL1 || || Transaldolase; protein present in exponential and stationary growth phase yeast cultures; oxidative stress-induced via Cap1; induced by nitric oxide independent of Yhb1p; sumoylation target; rat catheter biofilm repressed || 1 0.70 0.72 0.84 0.69 -0.59 -0.41 -0.73 -0.80 -0.51 -0.45 -0.61 -0.52 -0.35 -0.25 -0.53 -0.70
8211 || orf19.5520 || ASG7 || || a-cell specific protein of unknown function; two predicted transmembrane domains; member of conserved Mcm1 regulon; induced by alpha pheromone in SpiderM medium || 1 1.14 0.98 1.15 1.69 -0.97 -0.50 -1.22 -0.75 -0.26 -0.89 -1.10 -0.77 -1.23 -0.12 -1.01 -0.63
8212 || orf19.6627 || || || Protein of unknown function; possibly transcriptionally regulated upon hyphal formation || 1 0.67 0.73 0.94 1.23 -0.95 -0.38 -0.49 -0.26 -0.61 -0.24 -1.18 -0.85 -0.92 -0.74 -0.77 -0.20
8213 || orf19.6627 || || || Protein of unknown function; possibly transcriptionally regulated upon hyphal formation || 1 0.59 0.48 1.04 1.00 -1.41 -0.44 -0.81 -0.35 -0.84 -0.25 -1.66 -0.99 -1.29 -0.44 -1.15 -0.43
8214 || orf19.1743 || ACS1 || || Acetyl-CoA synthetase; induced by human neutrophils; fluconazole-repressed; regulated by Nrg1/Mig1; colony morphology-related gene regulation by Ssn6; only in stationary phase cultures; rat catheter biofilm repressed, Spider biofilm induced || 1 0.49 0.38 0.48 0.80 -0.60 -0.11 -0.37 -0.49 -0.42 -0.33 -0.93 -0.31 -0.38 -0.25 -0.98 -0.18
8215 || orf19.789 || PYC2 || || Putative pyruvate carboxylase; binds biotin cofactor; repressed by Ssk1 response regulator, by benomyl treatment, or in an azole-resistant strain overexpressing MDR1; stationary phase enriched protein; flow model biofilm repressed || 1 1.11 1.12 0.87 1.48 -1.45 -1.11 -1.21 -1.82 -1.13 -0.33 -1.66 -1.32 -0.93 -0.63 -1.76 -0.39
8216 || orf19.3156 || || || Protein of unknown function; induced by Mnl1 under weak acid stress || 1 0.17 0.10 0.56 0.30 -0.39 0.46 -0.81 -0.67 -0.10 -0.30 -0.34 -0.54 -0.51 -0.71 -0.51 -0.46
8217 || orf19.3156 || || || Protein of unknown function; induced by Mnl1 under weak acid stress || 1 0.39 0.19 0.38 0.17 -0.22 0.33 -0.92 -1.02 -0.32 -0.40 -0.69 -0.78 -0.54 -0.97 -0.60 -0.32
8218 || orf19.543 || FUM11 || || Fumarate hydratase; induced in high iron; protein in exponential and stationary-phase yeast cells, but higher in stationary phase; rat catheter biofilm repressed || 1 0.36 0.27 0.18 0.06 -0.04 0.31 -0.49 -0.71 -0.22 -0.22 -0.82 -0.49 -0.90 -0.64 -0.59 -0.53
8219 || orf19.543 || FUM11 || || Fumarate hydratase; induced in high iron; protein in exponential and stationary-phase yeast cells, but higher in stationary phase; rat catheter biofilm repressed || 1 0.07 0.01 0.08 0.00 -0.39 0.28 -0.69 -0.98 -0.54 -0.31 -1.12 -0.73 -1.22 -0.73 -1.02 -0.45
8220 || orf19.6654 || || || Predicted membrane transporter, member of the L-amino acid transporter-3 (LAT3) family, major facilitator superfamily (MFS) || 1 0.06 -0.32 0.52 0.59 -0.63 0.07 -1.54 -1.81 -1.07 -0.80 -1.63 -0.46 -1.62 -2.32 -1.40 -0.66
8221 || orf19.1582 || || || Predicted membrane transporter; member of the drug:proton antiporter (12 spanner) (DHA1) family, major facilitator superfamily (MFS); mRNA binds She3 || 1 0.05 -0.20 0.09 0.51 -0.20 -0.07 -0.78 -0.58 -0.50 -0.19 -0.73 -0.52 -0.63 -0.55 -0.74 -0.09
8222 || orf19.2986 || || || Ortholog of C. dubliniensis CD36 : Cd36_02750, C. parapsilosis CDC317 : CPAR2_106015, Candida tenuis NRRL Y-1498 : CANTEDRAFT_107500 and Debaryomyces hansenii CBS767 : DEHA2D08250g || 1 0.19 0.08 0.27 0.71 -0.70 0.64 -1.39 -0.76 -1.47 -1.30 -1.81 -1.64 -1.28 -1.61 -1.22 -0.92
8223 || orf19.4424 || PHO100 || || Putative inducible acid phosphatase; DTT-extractable and observed in culture supernatant in low-phosphate conditions; slight effect on murine virulence; virulence-group-correlated expression; N-glycosylated; F-12/CO2 early biofilm induced || 1 0.96 0.83 1.13 0.81 0.55 1.85 -5.57 -6.61 -6.03 -7.05 -6.68 -7.38 -2.99 -7.27 -5.77 -7.29
8224 || orf19.4424 || PHO100 || || Putative inducible acid phosphatase; DTT-extractable and observed in culture supernatant in low-phosphate conditions; slight effect on murine virulence; virulence-group-correlated expression; N-glycosylated; F-12/CO2 early biofilm induced || 1 1.13 1.04 1.68 1.23 0.76 2.33 -6.25 -6.97 -7.49 -7.19 -7.06 -7.90 -3.00 -7.25 -6.95 -7.55
8225 || orf19.762 || || || Ortholog of C. parapsilosis CDC317 : CPAR2_105580, C. dubliniensis CD36 : Cd36_04550, Lodderomyces elongisporus NRLL YB-4239 : LELG_03202 and Candida orthopsilosis Co 90-125 : CORT_0B06800 || 1 1.65 1.77 2.21 2.28 0.39 0.70 -4.52 -6.76 -8.62 -6.45 -5.36 -5.80 -5.66 -5.43 -6.08 -5.47
8226 || orf19.34 || GIT1 || || Glycerophosphoinositol permease; involved in utilization of glycerophosphoinositol as a phosphate source; Rim101-repressed; virulence-group-correlated expression || 1 1.29 1.11 1.71 1.48 0.25 1.87 -3.81 -4.47 -3.97 -3.48 -4.78 -4.06 -3.82 -4.27 -5.09 -4.83
8227 || orf19.34 || GIT1 || || Glycerophosphoinositol permease; involved in utilization of glycerophosphoinositol as a phosphate source; Rim101-repressed; virulence-group-correlated expression || 1 1.19 0.92 1.49 1.41 0.07 1.69 -4.01 -5.07 -4.47 -4.37 -4.84 -4.08 -4.19 -4.37 -4.86 -3.78
8228 || orf19.762 || || || Ortholog of C. parapsilosis CDC317 : CPAR2_105580, C. dubliniensis CD36 : Cd36_04550, Lodderomyces elongisporus NRLL YB-4239 : LELG_03202 and Candida orthopsilosis Co 90-125 : CORT_0B06800 || 1 1.76 1.81 2.19 2.16 0.35 0.62 -4.83 -5.79 -6.03 -5.62 -6.06 -6.32 -4.81 -6.63 -4.92 -5.05
8229 || orf19.2681 || RBT7 || || Protein with similarity to RNase T2 enzymes; has putative secretion signal; expression is Tup1-repressed || 1 1.22 0.89 1.61 1.66 1.18 1.59 -4.79 -5.66 -5.13 -6.28 -4.67 -4.88 -4.13 -6.78 -3.56 -4.03
8230 || orf19.2681 || RBT7 || || Protein with similarity to RNase T2 enzymes; has putative secretion signal; expression is Tup1-repressed || 1 1.32 1.16 2.12 2.07 1.05 1.80 -4.92 -5.40 -4.91 -4.43 -4.58 -4.89 -4.24 -5.70 -3.19 -4.19
8231 || orf19.2681 || RBT7 || || Protein with similarity to RNase T2 enzymes; has putative secretion signal; expression is Tup1-repressed || 1 1.19 1.01 1.86 1.65 1.16 1.49 -3.24 -3.31 -4.47 -4.17 -3.84 -3.84 -3.49 -3.99 -2.68 -3.50
8232 || orf19.2681 || RBT7 || || Protein with similarity to RNase T2 enzymes; has putative secretion signal; expression is Tup1-repressed || 1 0.62 0.78 1.90 1.73 0.80 1.45 -2.02 -2.77 -3.15 -3.60 -2.95 -3.51 -2.83 -3.51 -2.26 -2.62
8233 || orf19.2681 || RBT7 || || Protein with similarity to RNase T2 enzymes; has putative secretion signal; expression is Tup1-repressed || 1 1.17 1.03 1.88 1.84 1.22 1.75 -3.00 -3.32 -3.78 -4.35 -3.23 -3.81 -2.92 -4.58 -2.47 -2.50
8234 || orf19.2220 || || || Protein of unknown function; Hap43-repressed gene; by Rgt1; repressed in Spider biofilms by Bcr1, Tec1, Brg1, Rob1 and induced by Efg1, Ndt80; Spider biofilm induced || 1 0.05 0.30 1.73 1.26 2.50 1.76 -3.56 -3.93 -3.96 -3.92 -4.12 -4.29 -3.32 -4.66 -1.70 -3.27
8235 || orf19.2220 || || || Protein of unknown function; Hap43-repressed gene; by Rgt1; repressed in Spider biofilms by Bcr1, Tec1, Brg1, Rob1 and induced by Efg1, Ndt80; Spider biofilm induced || 1 0.30 0.49 2.02 1.36 2.81 1.89 -5.54 -5.52 -4.48 -3.90 -6.56 -5.58 -4.20 -7.07 -1.89 -4.75
8236 || orf19.2220 || || || Protein of unknown function; Hap43-repressed gene; by Rgt1; repressed in Spider biofilms by Bcr1, Tec1, Brg1, Rob1 and induced by Efg1, Ndt80; Spider biofilm induced || 1 0.18 0.35 1.80 1.20 2.72 1.87 -5.46 -6.19 -5.19 -4.33 -6.93 -5.51 -4.46 -5.57 -1.90 -5.31
8237 || orf19.2006 || || || Ortholog(s) have fungal-type vacuole membrane localization || 1 -0.08 0.05 0.14 0.20 0.22 0.38 -0.66 -0.59 -0.46 -0.50 -0.42 -0.64 -0.34 -0.20 -0.24 -0.41
8238 || orf19.655 || PHO84 || || High-affinity phosphate transporter; transcript regulated by white-opaque switch; Hog1, ciclopirox olamine or alkaline induced; caspofungin, stress repressed; upregulated in RHE model; Spider and flow model biofilm induced, Hap43-induced || 1 1.09 1.11 1.76 2.43 0.12 1.55 -4.82 -6.15 -4.41 -4.24 -5.23 -1.91 -0.91 -3.86 -1.98 -5.48
8239 || orf19.655 || PHO84 || || High-affinity phosphate transporter; transcript regulated by white-opaque switch; Hog1, ciclopirox olamine or alkaline induced; caspofungin, stress repressed; upregulated in RHE model; Spider and flow model biofilm induced, Hap43-induced || 1 0.96 0.86 1.41 1.70 -0.03 1.38 -4.43 -5.57 -4.15 -3.74 -4.79 -1.27 -1.00 -3.19 -1.43 -5.36
8240 || orf19.655 || PHO84 || || High-affinity phosphate transporter; transcript regulated by white-opaque switch; Hog1, ciclopirox olamine or alkaline induced; caspofungin, stress repressed; upregulated in RHE model; Spider and flow model biofilm induced, Hap43-induced || 1 1.40 1.18 2.04 2.16 0.35 1.62 -4.46 -5.02 -4.22 -3.05 -4.34 -1.44 -0.78 -3.26 -1.40 -5.68
8241 || orf19.655 || PHO84 || || High-affinity phosphate transporter; transcript regulated by white-opaque switch; Hog1, ciclopirox olamine or alkaline induced; caspofungin, stress repressed; upregulated in RHE model; Spider and flow model biofilm induced, Hap43-induced || 1 1.33 1.21 2.06 0.14 1.42 -2.91 -3.72 -3.65 -3.64 -3.98 -1.31 -0.95 -3.17 -1.22 -4.52
8242 || orf19.655 || PHO84 || || High-affinity phosphate transporter; transcript regulated by white-opaque switch; Hog1, ciclopirox olamine or alkaline induced; caspofungin, stress repressed; upregulated in RHE model; Spider and flow model biofilm induced, Hap43-induced || 1 1.08 0.90 1.63 -0.35 1.18 -2.84 -3.27 -2.98 -3.44 -3.88 -1.69 -0.48 -2.61 -1.41 -5.12
8243 || orf19.442 || || || Ortholog of Candida guilliermondii ATCC 6260 : PGUG_05525, Candida lusitaniae ATCC 42720 : CLUG_03378 and Candida albicans WO-1 : CAWG_00876 || 1 0.12 0.53 1.22 1.21 -0.44 0.31 -1.08 -0.74 -0.49 -0.55 -1.47 -1.73 -0.97 -1.75 -1.21 -2.47
8244 || orf19.7514 || PCK1 || || Phosphoenolpyruvate carboxykinase; glucose, C-source, yeast-hypha, Hap43 regulated; fluconazole, phagocytosis, H2O2, oral candidasis, Spider/rat catheter/flow model biofilm induced; repressed in biofilm by Bcr1, Tec1, Ndt80, Rob1, Brg1 || 1 0.76 0.79 1.82 2.06 0.07 -0.08 -1.65 -1.29 -1.32 -1.30 -4.32 -3.51 -2.12 -3.26 -0.96 -3.94
8245 || orf19.7514 || PCK1 || || Phosphoenolpyruvate carboxykinase; glucose, C-source, yeast-hypha, Hap43 regulated; fluconazole, phagocytosis, H2O2, oral candidasis, Spider/rat catheter/flow model biofilm induced; repressed in biofilm by Bcr1, Tec1, Ndt80, Rob1, Brg1 || 1 1.04 1.04 1.95 1.97 0.22 0.24 -1.57 -1.28 -0.91 -1.00 -4.07 -2.86 -2.11 -2.64 -0.70 -3.12
8246 || orf19.7514 || PCK1 || || Phosphoenolpyruvate carboxykinase; glucose, C-source, yeast-hypha, Hap43 regulated; fluconazole, phagocytosis, H2O2, oral candidasis, Spider/rat catheter/flow model biofilm induced; repressed in biofilm by Bcr1, Tec1, Ndt80, Rob1, Brg1 || 1 1.08 1.25 2.35 0.37 0.37 -1.33 -1.11 -0.79 -0.99 -4.08 -3.07 -1.90 -2.68 -0.54 -3.22
8247 || orf19.7514 || PCK1 || || Phosphoenolpyruvate carboxykinase; glucose, C-source, yeast-hypha, Hap43 regulated; fluconazole, phagocytosis, H2O2, oral candidasis, Spider/rat catheter/flow model biofilm induced; repressed in biofilm by Bcr1, Tec1, Ndt80, Rob1, Brg1 || 1 1.17 1.28 2.30 0.33 0.41 -1.33 -1.12 -0.65 -0.87 -3.75 -2.87 -1.76 -2.50 -0.49 -3.50
8248 || orf19.7514 || PCK1 || || Phosphoenolpyruvate carboxykinase; glucose, C-source, yeast-hypha, Hap43 regulated; fluconazole, phagocytosis, H2O2, oral candidasis, Spider/rat catheter/flow model biofilm induced; repressed in biofilm by Bcr1, Tec1, Ndt80, Rob1, Brg1 || 1 1.33 1.19 2.03 2.14 0.41 0.25 -1.18 -1.01 -0.81 -1.01 -3.99 -3.14 -1.78 -3.07 -0.63 -3.70
8249 || orf19.2401 || || || Ortholog(s) have cysteine-type endopeptidase activity || 1 0.22 0.07 0.15 0.19 0.31 0.28 -0.32 -0.48 -0.40 -0.62 -0.89 -0.48 -0.23 -0.53 0.02 -0.36
8250 || orf19.2220 || || || Protein of unknown function; Hap43-repressed gene; by Rgt1; repressed in Spider biofilms by Bcr1, Tec1, Brg1, Rob1 and induced by Efg1, Ndt80; Spider biofilm induced || 1 0.24 0.39 1.65 1.40 2.39 1.65 -2.09 -2.40 -1.48 -2.06 -3.21 -2.17 -2.27 -2.68 -1.34 -2.49
8251 || orf19.265 || || || Protein with a ribonuclease III domain; flow model biofilm induced; Spider biofilm induced || 1 1.36 1.23 1.50 0.85 0.87 1.87 -2.75 -4.05 -1.96 -2.68 -4.77 -4.89 -2.25 -2.99 -1.16 -3.94
8252 || orf19.4979 || KNS1 || || Protein kinase involved in negative regulation of PolIII transcription; effector kinase of the TOR signaling pathway, phosphorylates Rpc53p to regulate ribosome and tRNA biosynthesis; Spider and flow model biofilm induced || 1 0.68 0.51 1.25 1.00 1.10 1.68 -1.92 -1.84 -0.77 -1.29 -3.61 -1.68 -0.51 -0.47 -0.44 -2.52
8253 || orf19.4979 || KNS1 || || Protein kinase involved in negative regulation of PolIII transcription; effector kinase of the TOR signaling pathway, phosphorylates Rpc53p to regulate ribosome and tRNA biosynthesis; Spider and flow model biofilm induced || 1 0.60 0.50 1.09 0.83 0.86 1.65 -1.53 -1.66 -0.80 -1.15 -3.27 -2.25 -0.47 -0.46 -0.26 -2.77
8254 || orf19.4979 || KNS1 || || Protein kinase involved in negative regulation of PolIII transcription; effector kinase of the TOR signaling pathway, phosphorylates Rpc53p to regulate ribosome and tRNA biosynthesis; Spider and flow model biofilm induced || 1 0.62 0.34 0.95 0.89 0.79 1.42 -1.85 -1.77 -1.22 -1.29 -3.09 -2.10 -0.53 -0.61 -0.21 -2.30
8255 || orf19.4979 || KNS1 || || Protein kinase involved in negative regulation of PolIII transcription; effector kinase of the TOR signaling pathway, phosphorylates Rpc53p to regulate ribosome and tRNA biosynthesis; Spider and flow model biofilm induced || 1 0.44 0.42 0.77 0.91 0.77 1.40 -1.88 -1.84 -1.00 -1.26 -3.51 -2.08 -0.62 -0.47 -0.16 -3.43
8256 || orf19.4976 || || || Ortholog of Candida albicans WO-1 : CAWG_00105 || 1 0.64 0.78 0.90 1.14 1.72 2.13 -1.76 -2.44 -1.71 -1.37 -2.76 -2.51 -1.94 -1.38 -0.28 -2.87
8257 || orf19.4976 || || || Ortholog of Candida albicans WO-1 : CAWG_00105 || 1 0.70 0.71 0.97 1.19 1.63 2.25 -1.56 -1.95 -1.73 -1.30 -2.91 -2.30 -1.77 -1.48 -0.09 -2.46
8258 || orf19.4976 || || || Ortholog of Candida albicans WO-1 : CAWG_00105 || 1 1.02 1.00 1.23 1.12 1.95 2.20 -1.86 -2.00 -1.23 -1.75 -2.78 -2.78 -1.20 -1.65 -0.24 -2.88
8259 || orf19.4976 || || || Ortholog of Candida albicans WO-1 : CAWG_00105 || 1 0.80 0.89 1.30 1.22 1.75 2.14 -1.52 -2.09 -1.60 -1.67 -3.27 -2.83 -1.26 -1.95 -0.14 -4.43
8260 || orf19.265 || || || Protein with a ribonuclease III domain; flow model biofilm induced; Spider biofilm induced || 1 1.79 1.95 2.11 1.47 1.26 2.49 -1.08 -2.15 -1.19 -2.01 -3.23 -3.36 -1.17 -2.14 -0.14 -3.04
8261 || orf19.4976 || || || Ortholog of Candida albicans WO-1 : CAWG_00105 || 1 1.08 0.96 1.46 1.48 1.79 2.42 -1.63 -0.35 -0.87 -1.48 -3.23 -2.51 -1.18 -1.84 -0.08 -3.22
8262 || orf19.4189 || || || Has domain(s) with predicted hydrolase activity || 1 0.97 0.78 1.15 0.70 1.34 2.47 -2.40 -2.00 -1.55 -1.80 -4.10 -2.74 0.05 -2.29 -2.70 -4.93
8263 || orf19.3483 || || || Putative phosphatidyl glycerol phospholipase C; Plc1-regulated; flow model biofilm induced; Spider biofilm induced || 1 0.72 0.69 0.31 0.55 0.14 1.25 -0.65 -1.50 -1.03 -1.08 -2.72 -2.08 -0.51 -0.85 -1.72 -2.58
8264 || orf19.4476 || || || Protein with a NADP-dependent oxidoreductase domain; transcript induced by ketoconazole; rat catheter and Spider biofilm induced || 1 0.71 0.75 1.52 1.43 0.87 1.58 -1.88 -2.57 -1.54 -1.53 -4.41 -3.24 0.46 -1.12 -1.25 -2.62
8265 || orf19.1830 || || || Protein of unknown function; Hap43-induced; rat catheter and Spider biofilm induced || 1 1.12 1.14 1.93 1.93 0.55 1.19 -1.43 -2.24 -1.41 -1.02 -4.10 -2.98 0.67 -0.48 0.06 -2.68
8266 || orf19.1830 || || || Protein of unknown function; Hap43-induced; rat catheter and Spider biofilm induced || 1 0.56 0.46 1.53 1.70 -0.23 0.94 -1.60 -2.47 -1.59 -0.98 -4.09 -3.26 0.25 -0.66 0.04 -3.41
8267 || orf19.1830 || || || Protein of unknown function; Hap43-induced; rat catheter and Spider biofilm induced || 1 0.66 0.55 1.49 1.76 -0.06 0.81 -1.61 -2.73 -1.92 -1.10 -4.30 -3.33 0.34 -0.77 0.12 -3.88
8268 || orf19.1830 || || || Protein of unknown function; Hap43-induced; rat catheter and Spider biofilm induced || 1 1.14 0.98 1.69 1.78 0.19 0.55 -1.58 -2.92 -1.86 -1.14 -4.43 -3.20 0.30 -0.84 -0.31 -2.94
8269 || orf19.1830 || || || Protein of unknown function; Hap43-induced; rat catheter and Spider biofilm induced || 1 1.21 1.14 1.53 1.89 0.13 0.33 -1.34 -2.70 -2.07 -1.59 -4.14 -4.09 0.59 -1.05 -0.07 -2.95
8270 || orf19.1486 || || || Protein with a life-span regulatory factor domain; regulated by Sef1, Sfu1, and Hap43; flow model biofilm induced; Spider biofilm induced || 1 1.40 1.30 1.52 1.01 0.08 1.17 -0.76 -2.33 -1.26 -1.03 -2.91 -2.56 -0.41 -0.13 0.51 -2.49
8271 || orf19.1486 || || || Protein with a life-span regulatory factor domain; regulated by Sef1, Sfu1, and Hap43; flow model biofilm induced; Spider biofilm induced || 1 0.98 0.95 1.06 0.54 -0.15 0.85 -1.06 -2.56 -1.51 -1.35 -3.08 -2.71 -0.82 -0.26 0.32 -2.94
8272 || orf19.4773 || AOX2 || || Alternative oxidase; cyanide-resistant respiration; induced by antimycin A, oxidants; growth; Hap43, chlamydospore formation repressed; rat catheter, Spider biofilm induced; regulated in Spider biofilms by Bcr1, Tec1, Ndt80, Brg1 || 1 1.20 1.27 0.70 0.49 1.24 2.51 -1.48 -2.76 -0.50 -4.32 -7.34 -7.13 -1.99 -2.07 -0.84 -5.43
8273 || orf19.4773 || AOX2 || || Alternative oxidase; cyanide-resistant respiration; induced by antimycin A, oxidants; growth; Hap43, chlamydospore formation repressed; rat catheter, Spider biofilm induced; regulated in Spider biofilms by Bcr1, Tec1, Ndt80, Brg1 || 1 0.77 0.96 0.57 0.04 0.88 2.30 -1.60 -2.79 -0.55 -4.49 -7.02 -6.50 -2.28 -2.27 -1.11 -5.36
8274 || orf19.1523 || FMO1 || || Putative oxidoreductase; mutation confers hypersensitivity to toxic ergosterol analog, and to amphotericin B || 1 0.05 0.18 0.90 1.07 0.04 0.97 -0.51 -1.22 -1.37 -0.97 -2.23 -2.62 -0.88 -0.42 -0.64 -1.11
8275 || orf19.5622 || GLC3 || || Putative 1,4-glucan branching enzyme; fluconazole-induced; colony morphology-related gene regulation by Ssn6; stationary phase enriched protein || 1 0.03 0.00 0.57 0.64 0.17 0.50 -0.68 -0.34 0.10 -0.56 -1.49 -0.96 -0.29 -0.29 0.27 -0.91
8276 || orf19.4774 || AOX1 || || Alternative oxidase; low abundance; constitutively expressed; one of two isoforms (Aox1p and Aox2p); involved in a cyanide-resistant respiratory pathway present in plants, protists, and some fungi, absent in S. cerevisiae; Hap43p-repressed || 1 0.50 0.57 1.00 1.16 1.21 1.81 -0.31 0.03 -0.62 -1.30 -1.33 -1.30 -1.50 -0.59 0.08 -1.65
8277 || orf19.4774 || AOX1 || || Alternative oxidase; low abundance; constitutively expressed; one of two isoforms (Aox1p and Aox2p); involved in a cyanide-resistant respiratory pathway present in plants, protists, and some fungi, absent in S. cerevisiae; Hap43p-repressed || 1 0.07 0.14 0.87 0.81 0.86 1.75 -0.51 -0.41 -0.95 -1.63 -1.72 -1.03 -1.90 -0.47 -0.12 -1.63
8278 || orf19.4774 || AOX1 || || Alternative oxidase; low abundance; constitutively expressed; one of two isoforms (Aox1p and Aox2p); involved in a cyanide-resistant respiratory pathway present in plants, protists, and some fungi, absent in S. cerevisiae; Hap43p-repressed || 1 0.57 0.64 1.17 1.43 0.79 1.43 -0.84 -0.71 -0.70 -1.52 -1.97 -1.20 -1.41 -0.71 -0.47 -1.73
8279 || orf19.3131 || OYE32 || || NAD(P)H oxidoreductase family protein; induced by nitric oxide, amphotericin B, oxidative stress via Cap1; upregulation associated with MDR1 overexpression or benomyl treatment; macrophage-downregulated protein; Spider biofilm induced || 1 -0.13 -0.09 0.35 0.35 0.56 1.43 -0.28 -0.81 0.08 -0.65 -1.73 -1.15 -0.97 -1.07 -0.20 -1.13
8280 || orf19.3131 || OYE32 || || NAD(P)H oxidoreductase family protein; induced by nitric oxide, amphotericin B, oxidative stress via Cap1; upregulation associated with MDR1 overexpression or benomyl treatment; macrophage-downregulated protein; Spider biofilm induced || 1 -0.55 -0.45 0.00 -0.11 0.29 1.24 -0.47 -1.04 -0.53 -1.06 -2.23 -1.34 -1.65 -1.34 -0.40 -1.50
8281 || orf19.7283 || || || Protein of unknown function; rat catheter and Spider biofilm induced || 1 -0.60 -0.58 0.47 0.16 1.13 1.85 -1.02 -1.35 -0.62 -1.58 -1.74 -1.52 -1.17 -1.65 -0.23 -2.38
8282 || orf19.1641 || || || Ortholog(s) have cytosol, extracellular region, nucleus localization || 1 -0.14 -0.07 0.86 0.02 0.78 1.48 -1.13 -1.00 -1.13 -1.58 -1.61 -0.43
8283 || orf19.4774 || AOX1 || || Alternative oxidase; low abundance; constitutively expressed; one of two isoforms (Aox1p and Aox2p); involved in a cyanide-resistant respiratory pathway present in plants, protists, and some fungi, absent in S. cerevisiae; Hap43p-repressed || 1 0.12 0.09 0.55 0.57 0.86 1.29 -0.63 -0.44 -1.37 -1.76 -1.66 -1.84 -1.72 -1.06 -0.38 -2.68
8284 || orf19.4774 || AOX1 || || Alternative oxidase; low abundance; constitutively expressed; one of two isoforms (Aox1p and Aox2p); involved in a cyanide-resistant respiratory pathway present in plants, protists, and some fungi, absent in S. cerevisiae; Hap43p-repressed || 1 -0.25 -0.12 0.27 0.50 0.58 1.21 -0.77 -0.79 -1.47 -2.11 -1.88 -1.81 -2.21 -1.04 -0.24 -2.02
8285 || orf19.3340 || SOD2 || || Mitochondrial Mn-containing superoxide dismutase; protection against oxidative stress; homotetramer active; N-terminal 34 amino acids removed on mitochondrial import; H2O2-induced via Cap1p; Hap43p-, alkaline-downregulated, farnesol-induced || 1 -0.26 -0.29 0.23 0.60 0.63 0.76 -0.46 -0.47 -0.81 -0.41 -0.98 -0.66 -1.20 -1.15 0.46 -0.99
8286 || orf19.3340 || SOD2 || || Mitochondrial Mn-containing superoxide dismutase; protection against oxidative stress; homotetramer active; N-terminal 34 amino acids removed on mitochondrial import; H2O2-induced via Cap1p; Hap43p-, alkaline-downregulated, farnesol-induced || 1 -0.10 -0.19 -0.15 0.25 0.74 0.55 -0.54 -0.58 -1.13 -0.69 -1.10 -0.79 -0.71 -0.97 0.48 -1.49
8287 || orf19.6947 || GTT11 || || Glutathione S-transferase, localized to ER; induced in exponentially growing cells, under oxidative stress; induced by nitric oxide; Spider biofilm induced || 1 0.06 0.36 0.14 0.19 0.62 0.41 -0.31 -0.60 -0.56 -0.48 -0.97 -0.34 -0.68 -0.62 0.42 -1.22
8288 || orf19.359 || GTT12 || || Ortholog(s) have glutathione peroxidase activity, glutathione transferase activity, role in glutathione metabolic process and endoplasmic reticulum, mitochondrial outer membrane, plasma membrane localization || 1 0.41 0.32 0.28 0.31 0.70 0.52 -0.34 -0.66 -0.46 -0.59 -0.85 -0.34 -0.68 -0.96 0.51 -1.18
8289 || CaalfMp01 || COX2 || || Subunit II of cytochrome c oxidase, which is the terminal member of the mitochondrial inner membrane electron transport chain; one of three mitochondrially-encoded subunits || 1 0.06 0.17 -0.36 0.07 0.60 0.63 -0.67 -1.04 -0.56 -0.74 -1.12 -0.81 -0.28 -0.49 -0.03 -0.56
8290 || orf19.1641 || || || Ortholog(s) have cytosol, extracellular region, nucleus localization || 1 -0.01 0.14 0.27 0.12 1.22 1.51 -1.77 -1.61 -1.53 -0.98 -2.72 -3.14 -1.13 -1.46 -0.20 -1.07
8291 || orf19.7324 || THI13 || || Thiamin pyrimidine synthase; synthesis of the thiamine precursor hydroxymethylpyrimidine phosphate; single-turnover enzyme that provides histidine for HMP-P formation; induced by nitric oxide independent of Yhb1; Spider biofilm induced || 1 0.83 0.98 1.31 1.41 0.47 0.77 -1.64 -2.48 -0.81 -1.35 -2.29 -0.79 -1.91 -1.27 -1.44 -1.03
8292 || orf19.7324 || THI13 || || Thiamin pyrimidine synthase; synthesis of the thiamine precursor hydroxymethylpyrimidine phosphate; single-turnover enzyme that provides histidine for HMP-P formation; induced by nitric oxide independent of Yhb1; Spider biofilm induced || 1 0.91 0.95 1.30 1.28 0.40 0.74 -1.54 -2.39 -0.71 -1.29 -2.32 -0.88 -1.76 -1.34 -1.69 -0.84
8293 || orf19.5180 || PRX1 || || Thioredoxin peroxidase; transcriptionally induced by interaction with macrophage; fluconazole induced; Fkh2p-downregulated; caspofungin repressed; protein present in exponential and stationary growth phase yeast cultures || 1 0.58 0.47 1.38 1.52 -1.38 0.83 -0.95 -1.01 -1.11 -1.23 -0.99 -1.01 -0.97 -1.69 0.34 -1.04
8294 || orf19.5180 || PRX1 || || Thioredoxin peroxidase; transcriptionally induced by interaction with macrophage; fluconazole induced; Fkh2p-downregulated; caspofungin repressed; protein present in exponential and stationary growth phase yeast cultures || 1 0.52 0.56 1.67 1.89 -1.44 0.72 -0.94 -0.83 -1.18 -1.35 -0.87 -1.08 -1.04 -2.56 0.03 -1.20
8295 || orf19.988 || || || Protein of unknown function; oral infection upregulated gene; upregulated in strains from HIV+ patients with oral candidiasis; mutants have reduced ability to damage oral epithelial cells; transcript possibly regulated upon hyphal formation || 1 -0.07 -0.12 0.38 0.70 -0.40 0.23 -0.45 -0.47 -0.46 -0.74 -0.46 -0.39 -0.69 -0.76 -0.45 -0.50
8296 || orf19.753 || MNN15 || || Putative alpha-1,3-mannosyltransferase; predicted role in protein O-linked glycosylation; Spider biofilm induced || 1 0.13 0.08 0.52 0.73 -0.40 0.30 -0.65 -0.81 -0.61 -1.16 -0.89 -0.37 -0.46 -0.81 -0.07 -0.65
8297 || orf19.3414 || SUR7 || || Protein required for normal cell wall, plasma membrane, cytoskeletal organization, endocytosis; localizes to eisosome subdomains of plasma membrane; four transmembrane motifs; mutant shows ectopic, chitin-rich cell wall; fluconazole-induced || 1 0.03 -0.09 0.41 0.83 -0.70 -0.07 -1.32 -0.91 -0.99 -0.84 -0.93 -0.65 -0.53 -0.95 0.05 -0.76
8298 || orf19.2176 || IFM3 || || Protein with a 2-hydroxyacid dehydrogenase catalytic domain; Hap43-repressed; Plc1-regulated; overlaps orf19.2177 || 1 0.10 -0.23 0.39 0.73 -0.16 -0.21 -0.94 -0.63 -0.15 -1.08 -0.31 -0.74 -0.08 -0.95 0.01 -0.44
8299 || orf19.52 || || || Ortholog(s) have role in cellular iron ion homeostasis and mitochondrion localization || 1 -0.01 -0.23 0.53 0.61 -0.34 -0.25 -0.47 -0.63 -0.04 -0.62 -0.78 -0.33 -0.31 -0.55 0.04 -0.58
8300 || orf19.5710 || || || Nucleoporin component of central core of the nuclear pore complex; mRNA binds She3 || 1 -0.04 0.15 0.36 0.75 -0.17 -0.16 -0.80 -0.85 -0.06 -0.46 -0.55 -0.30 -0.22 -0.48 -0.03 -0.25
8301 || orf19.552 || || || Ortholog of a S. cerevisiae Atg22; a vacuolar integral membrane protein required for efflux of amino acids during autophagic body breakdown in the vacuole; possibly an essential gene, disruptants not obtained by UAU1 method || 1 -0.20 -0.10 0.62 0.71 -0.17 0.00 -0.96 -1.01 0.20 -0.79 -0.79 -0.57 -0.22 -0.64 -0.20 -0.43
8302 || orf19.2425 || HGT18 || || Putative glucose transporter of the major facilitator superfamily; the C. albicans glucose transporter family comprises 20 members; 12 probable membrane-spanning segments; expressed in rich medium with 2% glucose || 1 -0.09 -0.05 0.61 0.47 -0.12 0.29 -0.67 -0.63 -0.09 -0.41 -0.71 -0.45 -0.06 -0.48 0.01 -0.21
8303 || orf19.7576 || || || Ortholog of S. pombe atl1 alkyltransferase-like protein; mutants are viable; Spider biofilm induced || 1 0.09 -0.02 0.46 0.33 -0.16 0.23 -0.39 -0.31 0.01 -0.55 -0.61 -0.46 0.19 -0.32 -0.18 -0.38
8304 || orf19.3380 || HWP2 || || GPI-anchored, glycosylated cell wall protein; required for biofilm formation, adhesion, filamentous growth on some media; expressed in hyphae; mutant delayed in virulence; regulated by Efg1, Tup1; similar to Hwp1 and Rbt1 domains || 1 0.34 0.27 0.85 0.95 -0.12 0.09 -0.74 -0.83 -0.08 -0.98 -0.78 -0.71 0.11 -0.83 -0.79 -0.49
8305 || orf19.2074 || || || Ortholog of Candida albicans WO-1 : CAWG_03833 || 1 0.09 0.09 0.62 0.43 0.11 0.10 -0.53 -0.51 -0.14 -1.04 -0.72 -0.74 -0.06 -1.06 -0.46 -0.71
8306 || orf19.1728 || || || Ortholog of C. dubliniensis CD36 : Cd36_81190, C. parapsilosis CDC317 : CPAR2_503840, Debaryomyces hansenii CBS767 : DEHA2A09042g and Pichia stipitis Pignal : PICST_42519 || 1 -0.02 -0.03 0.28 0.43 0.02 -0.01 -0.54 -0.44 0.22 -0.88 -0.51 -0.38 -0.02 -0.60 -0.39 -0.75
8307 || orf19.6378 || TRM9 || || Putative tRNA methyltransferase; repressed during the mating process || 1 -0.33 -0.44 0.98 0.85 -0.55 0.03 -0.63 -0.64 -0.36 -1.12 -0.64 -0.96 -0.02 -1.20 -0.17 -1.21
8308 || orf19.475 || || || Putative rRNA processing protein; rat catheter biofilm induced || 1 -0.24 -0.10 1.30 0.76 -0.37 0.26 -0.97 -0.91 -0.16 -0.84 -1.11 -0.77 -0.06 -1.37 -0.32 -1.19
8309 || orf19.3565 || || || Ortholog of C. dubliniensis CD36 : Cd36_19830, C. parapsilosis CDC317 : CPAR2_206470, Candida tenuis NRRL Y-1498 : CANTEDRAFT_113899 and Debaryomyces hansenii CBS767 : DEHA2C05676g || 1 -0.13 -0.05 0.34 0.21 -0.02 0.05 -0.41 -0.27 -0.15 -0.31 -0.18 -0.24 0.04 -0.32 0.02 -0.30
8310 || orf19.3785 || || || DnaJ chaperone domain protein; role in pre-mRNA splicing; Spider biofilm induced || 1 0.02 0.05 0.56 0.61 0.09 0.46 -0.48 -0.53 -0.49 -1.06 -0.45 -0.37 0.00 -0.81 -0.05 -0.42
8311 || orf19.2074 || || || Ortholog of Candida albicans WO-1 : CAWG_03833 || 1 -0.11 -0.11 0.39 0.27 -0.05 0.17 -0.52 -0.36 -0.47 -1.04 -0.54 -0.54 0.05 -0.55 -0.24 -0.38
8312 || orf19.2074 || || || Ortholog of Candida albicans WO-1 : CAWG_03833 || 1 0.11 0.04 0.62 1.07 0.03 0.08 -0.21 -0.40 -0.37 -0.93 -0.64 -0.64 0.07 -0.80 -0.25 -0.48
8313 || orf19.1349 || || || Ortholog of C. dubliniensis CD36 : Cd36_22470, Candida tropicalis MYA-3404 : CTRG_01829 and Candida albicans WO-1 : CAWG_05920 || 1 -0.44 -0.43 0.46 0.63 -0.47 -0.11 -0.40 -0.44 -0.36 -0.95 -0.66 -0.71 -0.39 -1.16 -0.50 -0.72
8314 || orf19.4798 || || || Ortholog(s) have role in establishment of protein localization to plasma membrane and mitochondrion, plasma membrane localization || 1 0.10 -0.24 0.22 0.68 -0.07 -0.33 -0.09 -0.29 -0.07 -0.05 -0.57 -0.67 -0.26 -0.41 -0.28 -0.77
8315 || orf19.1239 || || || Secreted protein; exogenously expressed protein is a substrate for Kex2 processing in vitro; fluconazole-regulated; Spider biofilm induced || 1 -0.18 -0.34 1.06 1.46 -0.33 -1.02 -0.57 -0.90 -0.79 0.55 -0.73 -1.03 -0.24 -1.07 -0.85 -1.16
8316 || orf19.1239 || || || Secreted protein; exogenously expressed protein is a substrate for Kex2 processing in vitro; fluconazole-regulated; Spider biofilm induced || 1 0.43 0.55 1.40 2.11 0.39 -2.10 -1.85 -1.80 -2.10 0.78 -1.98 -4.42 -0.62 -2.39 -1.19 -3.07
8317 || orf19.1344 || || || Protein of unknown function; fluconazole-induced; Spider biofilm induced || 1 -0.12 -0.10 1.46 2.38 0.06 -2.13 -3.43 -2.63 -3.57 -1.12 -4.41 -4.36 0.41 -4.40 -1.22 -5.63
8318 || orf19.1344 || || || Protein of unknown function; fluconazole-induced; Spider biofilm induced || 1 0.67 0.77 2.17 2.95 0.86 -1.20 -1.57 -1.21 -3.15 -0.89 -2.56 -3.49 0.77 -3.48 -0.28 -3.89
8319 || orf19.4110 || || || Ortholog of C. dubliniensis CD36 : Cd36_20490, C. parapsilosis CDC317 : CPAR2_104180, Candida tenuis NRRL Y-1498 : CANTEDRAFT_116074 and Debaryomyces hansenii CBS767 : DEHA2F05148g || 1 -0.27 -0.17 0.21 0.40 0.12 -0.17 -0.38 -0.25 -0.31 -0.22 -0.40 -0.35 -0.00 -0.38 -0.19 -0.65
8320 || orf19.4587 || HGH1 || || Putative HMG1/2-related protein; transcript regulated by Mig1 || 1 -0.31 0.07 0.20 0.25 -0.14 -0.08 -0.40 -0.37 -0.14 -0.19 -0.63 -0.58 0.20 -0.56 -0.44 -0.83
8321 || orf19.4022 || SDH4 || || Succinate dehydrogenase, membrane subunit; induced in high iron || 1 0.18 0.46 0.28 0.17 -0.07 -0.24 -0.70 -0.58 -0.02 -0.07 -0.65 -0.50 0.33 -0.74 -0.20 -1.12
8322 || orf19.5704 || || || Ortholog(s) have rRNA binding activity, role in mitochondrial RNA processing, mitochondrial genome maintenance, rRNA metabolic process and mitochondrion localization || 1 -0.11 0.05 0.06 0.25 0.20 -0.26 -0.40 -0.34 -0.48 0.16 -0.58 -0.30 0.20 -0.72 -0.01 -1.22
8323 || orf19.6824 || TRY6 || || Helix-loop-helix transcription factor; regulator of yeast form adherence; required for yeast cell adherence to silicone substrate; Spider and F-12/CO2 biofilm induced; repressed by alpha pheromone in SpiderM medium || 1 -0.01 -0.16 1.34 0.70 -0.95 1.37 -3.65 -4.94 -1.04 -1.87 -5.26 -1.50 -0.09 -3.36 0.17 -5.04
8324 || orf19.6824 || TRY6 || || Helix-loop-helix transcription factor; regulator of yeast form adherence; required for yeast cell adherence to silicone substrate; Spider and F-12/CO2 biofilm induced; repressed by alpha pheromone in SpiderM medium || 1 0.31 0.11 1.24 0.89 -0.42 1.56 -2.46 -3.16 -0.72 -2.23 -3.25 -0.86 0.12 -2.87 0.74 -2.32
8325 || orf19.7472 || IFF4 || || Adhesin-like cell surface protein; putative GPI-anchor; null mutant germ tubes show decreased adhesion to plastic substrate; mutants are viable; Hap43-repressed gene || 1 -0.15 -0.32 0.30 0.84 -0.54 -0.19 -0.88 -1.01 -0.53 -1.01 -1.99 -1.01 -0.39 -0.05 -0.13 -0.69
8326 || orf19.1237 || ARO9 || || Aromatic transaminase; Ehrlich fusel oil pathway of aromatic alcohol biosynthesis; Rim101-dependent pH-regulation (alkaline induced); Hap43-induced gene || 1 -0.23 -0.29 -0.34 0.35 -0.79 0.31 -0.86 -1.12 -0.11 0.10 -1.81 -1.06 -0.37 0.18 0.45 -0.51
8327 || orf19.1237 || ARO9 || || Aromatic transaminase; Ehrlich fusel oil pathway of aromatic alcohol biosynthesis; Rim101-dependent pH-regulation (alkaline induced); Hap43-induced gene || 1 -0.11 -0.01 0.09 0.69 -0.82 0.39 -0.96 -0.99 -0.22 -0.17 -1.84 -0.66 -0.61 -0.08 -0.01 -0.10
8328 || orf19.1237 || ARO9 || || Aromatic transaminase; Ehrlich fusel oil pathway of aromatic alcohol biosynthesis; Rim101-dependent pH-regulation (alkaline induced); Hap43-induced gene || 1 0.23 0.17 0.30 0.67 -0.76 0.74 -0.43 -0.62 -0.06 -0.12 -2.01 -1.02 -0.12 0.01 -0.09 -0.29
8329 || orf19.2160 || NAG4 || || Putative transporter; fungal-specific; similar to Nag3p and to S. cerevisiae Ypr156Cp and Ygr138Cp; required for wild-type mouse virulence and wild-type cycloheximide resistance; gene cluster encodes enzymes of GlcNAc catabolism || 1 -0.12 0.06 0.86 1.11 -0.53 1.03 -0.52 -1.16 -0.83 -0.19 -4.10 -1.97 -1.14 -1.77 -1.71 -1.17
8330 || orf19.999 || GCA2 || || Predicted extracellular glucoamylase; induced by ketoconazole; possibly essential, disruptants not obtained by UAU1 method; promotes biofilm matrix formation; Spider biofilm induced; Bcr1-induced in RPMI a/a biofilms || 1 -0.18 -0.11 1.30 1.20 0.72 0.77 -0.86 -1.31 -0.35 -0.38 -3.03 -1.73 -1.06 -0.96 0.21 -1.67
8331 || orf19.4551 || CTN1 || || Carnitine acetyl transferase; required for growth on nonfermentable carbon sources, not for hyphal growth or virulence in mice; induced in macrophage; macrophage/pseudohyphal-repressed after 16 hr; rat catheter, Spider biofilm induced || 1 -0.05 -0.01 0.79 1.50 0.80 0.20 -0.20 -1.32 -0.45 -0.06 -2.62 -1.43 -1.28 -0.84 0.17 -1.33
8332 || orf19.4551 || CTN1 || || Carnitine acetyl transferase; required for growth on nonfermentable carbon sources, not for hyphal growth or virulence in mice; induced in macrophage; macrophage/pseudohyphal-repressed after 16 hr; rat catheter, Spider biofilm induced || 1 0.06 -0.09 0.76 1.13 0.95 0.34 -0.47 -2.02 -0.64 0.11 -5.36 -2.73 -1.57 -1.25 0.15 -3.33
8333 || orf19.4551 || CTN1 || || Carnitine acetyl transferase; required for growth on nonfermentable carbon sources, not for hyphal growth or virulence in mice; induced in macrophage; macrophage/pseudohyphal-repressed after 16 hr; rat catheter, Spider biofilm induced || 1 -0.00 -0.00 0.62 1.24 1.05 0.10 -0.68 -2.11 -0.18 0.19 -3.80 -2.25 -0.58 -0.82 -0.17 -1.40
8334 || orf19.4077 || MIT1 || || Mannosylinositol phosphorylceramide (MIPC) synthase catalytic subunit; sphingolipid biosynthesis; fluconazole, caspofungin induced; macrophage-repressed; Spider biofilm induced || 1 0.02 -0.31 0.08 0.04 0.26 -0.07 -0.45 -0.77 -0.13 -0.13 -1.43 -0.77 -0.78 -0.15 0.21 -0.55
8335 || orf19.5005 || OSM2 || || Putative mitochondrial fumarate reductase; regulated by Ssn6p, Gcn2p, and Gcn4p; Hog1p-downregulated; stationary phase enriched protein; Hap43p-repressed gene || 1 0.63 0.47 0.47 0.44 -0.31 0.36 -1.60 -1.22 -0.41 -0.75 -2.25 -0.37 -2.64 -2.94 -0.66 -1.95
8336 || orf19.5005 || OSM2 || || Putative mitochondrial fumarate reductase; regulated by Ssn6p, Gcn2p, and Gcn4p; Hog1p-downregulated; stationary phase enriched protein; Hap43p-repressed gene || 1 0.57 0.66 1.17 0.68 0.04 0.81 -1.18 -1.01 0.01 -0.25 -2.25 0.06 -2.44 -2.04 -0.34 -1.47
8337 || orf19.996 || || || Protein with a predicted leucine-rich repeat domain; possibly an essential gene, disruptants not obtained by UAU1 method || 1 0.54 0.61 0.44 0.44 0.43 0.82 -0.88 -0.80 -0.62 -0.10 -1.11 0.04 -1.09 -0.58 -0.46 -0.80
8338 || orf19.2467 || PRN1 || || Protein with similarity to pirins; induced by benomyl and in response to alpha pheromone in SpiderM medium; transcript induced by Mnl1 in weak acid stress; rat catheter and Spider biofilm induced || 1 0.51 0.68 0.82 0.26 0.47 0.92 -1.08 -1.11 -0.31 0.11 -0.71 -0.12 -0.78 -1.79 -0.07 -0.52
8339 || orf19.4538 || || || Ortholog(s) have mRNA binding, protein heterodimerization activity, role in mRNA cleavage, mRNA polyadenylation and U2 snRNP, mRNA cleavage factor complex localization || 1 0.05 0.01 0.47 -0.02 0.16 0.00 -0.70 -0.16 0.12 -0.48 -0.12 -0.77 -0.06 -0.61 -0.04 -0.31
8340 || orf19.6374 || || || Ortholog(s) have unfolded protein binding activity, role in mitochondrial proton-transporting ATP synthase complex assembly and integral to mitochondrial membrane, mitochondrial inner membrane localization || 1 -0.10 -0.09 0.27 -0.14 0.08 -0.16 -0.64 -0.45 0.12 -0.32 -0.41 -0.62 0.02 -0.42 -0.18 -0.59
8341 || orf19.3373 || || || Putative protein of unknown function; transcript upregulated in clinical isolates from HIV+ patients with oral candidiasis; Spider biofilm induced || 1 -0.18 -0.16 0.34 -0.02 -0.06 0.10 -0.86 -0.70 0.04 -0.94 -0.57 -0.98 -0.47 -0.48 -0.24 -0.92
8342 || orf19.1181 || || || Has domain(s) with predicted catalytic activity and membrane localization || 1 -0.26 -0.31 0.59 0.13 0.56 0.45 -0.52 -0.48 0.32 -0.01 -0.31 -0.78 -0.38 -0.71 -0.31 -0.99
8343 || orf19.6911 || || || Ortholog of Candida albicans WO-1 : CAWG_05482 || 1 -0.10 0.04 1.11 0.23 -0.03 0.44 -0.80 -0.46 0.89 0.09 -0.69 -1.06 0.22 -0.51 -0.32 -1.00
8344 || orf19.7601 || || || Putative mitochondrial 2' O-ribose methyltransferase; predicted role in methylation of U(2791) in 21S rRNA; Spider biofilm induced || 1 -0.09 -0.06 0.92 0.42 -0.09 0.20 -0.52 -0.28 0.10 0.09 -0.19 -0.80 0.20 -0.14 -0.06 -0.58
8345 || orf19.6532 || || || Ortholog(s) have FAD transmembrane transporter activity, role in FAD transport and mitochondrion localization || 1 -0.22 -0.12 0.47 -0.02 -0.09 -0.09 -0.25 -0.15 -0.00 -0.29 -0.29 -0.17 0.03 -0.30 -0.17 -0.57
8346 || orf19.1162.1 || || || Ortholog(s) have Golgi apparatus localization || 1 -0.20 -0.12 0.44 0.30 0.21 -0.05 -0.37 -0.17 0.23 -0.80 -0.59 -0.27 0.21 -1.22 -0.34 -1.28
8347 || orf19.2812 || || || Protein of unknown function; Spider biofilm induced || 1 0.18 -0.12 0.91 0.76 -0.23 0.64 0.57 -0.34 0.37 0.07 -1.83 -0.70 -0.12 -0.59 -0.54 -1.45
8348 || orf19.2812 || || || Protein of unknown function; Spider biofilm induced || 1 -0.24 -0.40 0.99 0.98 -0.28 0.84 -0.36 -0.41 0.26 -0.03 -1.71 -1.09 -0.37 -0.40 -0.87 -1.45
8349 || orf19.4507 || || || Protein of unknown function; Hap43-repressed; rat catheter biofilm repressed || 1 -0.14 -0.15 0.92 0.61 0.41 0.85 0.01 -0.39 0.67 -0.42 -1.35 -0.70 -0.41 -0.27 -0.31 -0.83
8350 || orf19.7313 || SSU1 || || Protein similar to S. cerevisiae Ssu1 sulfite transport protein; Tn mutation affects filamentous growth; regulated by Gcn2 and Gcn4; induced by nitric oxide; Hap43-repressed; Spider and flow model biofilm induced || 1 0.25 0.59 0.64 0.86 1.48 1.87 0.15 -0.53 0.95 -1.05 -1.43 -1.85 0.50 -0.39 -0.70 -1.22
8351 || orf19.7313 || SSU1 || || Protein similar to S. cerevisiae Ssu1 sulfite transport protein; Tn mutation affects filamentous growth; regulated by Gcn2 and Gcn4; induced by nitric oxide; Hap43-repressed; Spider and flow model biofilm induced || 1 0.83 0.24 0.76 0.77 0.92 2.03 0.33 -0.35 0.91 -1.12 -2.45 -2.29 -0.34 -0.57 -1.02 -1.89
8352 || orf19.4509 || || || Protein of unknown function || 1 0.43 0.30 0.81 0.53 0.68 1.09 0.33 -0.61 -0.77 -2.40 -0.86 0.15 -0.75 -2.06 -1.91
8353 || orf19.2376 || || || Has domain(s) with predicted DNA 5'-adenosine monophosphate hydrolase activity, DNA binding activity and role in DNA repair || 1 0.45 0.53 0.62 0.58 0.44 0.71 0.46 0.27 1.18 -0.18 -1.18 -0.70 0.45 -0.24 -1.02 -0.67
8354 || orf19.7331 || FCY24 || || Putative transporter; more similar to S. cerevisiae Tpn1, which is a vitamin B6 transporter, than to purine-cytosine permeases; transcription is regulated by Nrg1; Spider biofilm induced || 1 -0.19 0.17 0.43 0.36 0.59 0.97 0.00 -0.12 0.77 -0.54 -0.84 0.01 0.27 -0.40 -0.47 -0.39
8355 || orf19.554 || DIT2 || || Monooxygenase of the cytochrome P450 family; produces N,N'-bisformyl dityrosine from N-formyltyrosine; regulated by Nrg1, Mig1, and Tup1; role in chlamydospore formation; Spider biofilm induced || 1 -0.05 0.03 0.47 0.16 0.51 0.49 0.00 -0.23 0.68 -0.20 -0.77 0.01 -0.23 0.11 -0.11 -0.01
8356 || orf19.7319 || SUC1 || || Zinc-finger transcription factor; regulates alpha-glucosidase exression; complements S. cerevisiae suc2 for sucrose utilization and mal13 maltase defect; required for yeast cell adherence to silicone substrate; rat catheter biofilm induced || 1 0.50 0.43 0.63 0.51 0.13 0.30 -0.42 -0.54 0.14 -0.62 -0.60 -0.22 -0.01 -0.29 0.19 0.67
8357 || orf19.2082 || SAP30 || || Aspartic-type endopeptidase; involved in degradation of alpha pheromone; functional equivalent of S. cerevisiae Bar1; a-cell specific; induced by alpha pheromone || 1 1.62 0.85 0.36 0.12 1.21 -0.31 -1.21 0.20 -1.36 -0.87 0.03 0.42
8358 || orf19.1297 || || || Ortholog(s) have phosphatidylinositol-3-phosphate binding activity and role in CVT pathway, early endosome to Golgi transport, macroautophagy, mitochondrion degradation || 1 0.64 0.45 0.31 0.42 0.32 0.32 -0.23 -0.38 -0.07 -0.60 -0.37 -0.13 0.07 0.09 0.50 0.32
8359 || orf19.6920 || || || Protein of unknown function; induced during chlamydospore formation in both C. albicans and C. dubliniensis; Hap43-induced gene; Spider biofilm induced; F-12/CO2 early biofilm induced || 1 1.23 0.93 1.52 1.18 0.01 0.94 -0.21 -0.81 -0.08 -1.22 -0.26 -0.35 0.29 0.04 -0.05 -0.58
8360 || orf19.6920 || || || Protein of unknown function; induced during chlamydospore formation in both C. albicans and C. dubliniensis; Hap43-induced gene; Spider biofilm induced; F-12/CO2 early biofilm induced || 1 1.22 1.02 1.29 1.17 -0.46 1.24 -0.71 -2.30 -1.21 -1.94 -0.46 -0.37 0.20 -1.01 0.05 -0.55
8361 || orf19.1542 || HEX3 || || Protein similar to S. cerevisiae Hex3p, which is involved in DNA damage response; transposon mutation affects filamentous growth || 1 0.48 0.57 0.38 0.52 0.11 0.04 -0.13 -0.63 -0.45 -0.26 -0.45 0.16 -0.11 -0.23 0.13 -0.35
8362 || orf19.7561 || DEF1 || || RNA polymerase II regulator; role in filamentation, epithelial cell escape, dissemination in RHE model; induced by fluconazole, high cell density; Efg1/hyphal regulated; role in adhesion, hyphal growth on solid media; Spider biofilm induced || 1 2.00 2.06 0.60 -0.15 1.18 2.05 -1.14 -2.23 1.25 0.52 -3.32 -1.93 -0.01 -1.88 -1.66 -2.14
8363 || orf19.7561 || DEF1 || || RNA polymerase II regulator; role in filamentation, epithelial cell escape, dissemination in RHE model; induced by fluconazole, high cell density; Efg1/hyphal regulated; role in adhesion, hyphal growth on solid media; Spider biofilm induced || 1 1.46 1.50 0.06 -0.17 0.83 1.43 -1.02 -1.37 1.09 0.21 -2.25 -1.88 -0.08 -1.66 -1.34 -1.98
8364 || orf19.7561 || DEF1 || || RNA polymerase II regulator; role in filamentation, epithelial cell escape, dissemination in RHE model; induced by fluconazole, high cell density; Efg1/hyphal regulated; role in adhesion, hyphal growth on solid media; Spider biofilm induced || 1 1.83 1.87 -0.07 -0.69 1.04 1.64 -1.30 -2.34 0.94 0.29 -3.04 -2.47 -0.12 -1.86 -1.78 -2.19
8365 || orf19.7561 || DEF1 || || RNA polymerase II regulator; role in filamentation, epithelial cell escape, dissemination in RHE model; induced by fluconazole, high cell density; Efg1/hyphal regulated; role in adhesion, hyphal growth on solid media; Spider biofilm induced || 1 1.69 1.86 0.10 -0.41 0.83 1.56 -1.29 -2.37 0.71 -0.05 -3.31 -2.44 -0.12 -2.18 -1.73 -1.88
8366 || orf19.7561 || DEF1 || || RNA polymerase II regulator; role in filamentation, epithelial cell escape, dissemination in RHE model; induced by fluconazole, high cell density; Efg1/hyphal regulated; role in adhesion, hyphal growth on solid media; Spider biofilm induced || 1 1.30 1.45 -0.37 -1.43 0.77 1.27 -1.59 -2.60 0.84 0.07 -3.84 -2.44 -0.52 -2.12 -1.96 -2.40
8367 || orf19.3974 || PUT2 || || Putative delta-1-pyrroline-5-carboxylate dehydrogenase; alkaline upregulated; protein present in exponential and stationary growth phase yeast cultures; flow model biofilm induced; Spider biofilm induced || 1 0.14 0.00 -0.23 -0.02 0.06 -0.15 -0.29 -0.42 0.14 0.11 -0.99 -0.63 -0.22 -0.42 -0.63 -0.19
8368 || orf19.3974 || PUT2 || || Putative delta-1-pyrroline-5-carboxylate dehydrogenase; alkaline upregulated; protein present in exponential and stationary growth phase yeast cultures; flow model biofilm induced; Spider biofilm induced || 1 0.08 0.12 -0.12 0.23 0.13 -0.01 -0.35 -0.42 0.48 0.31 -0.96 -0.24 -0.41 -0.51 -0.53 -0.22
8369 || orf19.3238 || || || Ortholog of Candida albicans WO-1 : CAWG_01469 || 1 -0.55 0.03 0.01 0.35 -0.28 0.20 -0.85 -0.62 0.09 -0.56 -0.43 -0.29 -0.28 0.10 -0.89 -1.55
8370 || orf19.2704 || || || Ortholog of Candida albicans WO-1 : CAWG_03507 || 1 -0.00 -0.10 0.43 0.20 -0.26 0.21 -0.40 -0.26 -0.05 0.01 0.12 -0.05 -0.54 -0.07 -0.29 -0.44
8371 || orf19.4334 || PGA58 || || Putative GPI-anchored protein; transcription is positively regulated by Tbf1p || 1 -0.38 -0.67 0.45 0.48 -0.38 0.42 -0.54 -0.76 0.09 -0.19 -0.47 0.23 -1.00 -0.64 -0.72 -1.44
8372 || orf19.553 || || || Predicted membrane transporter, member of the drug:proton antiporter (12 spanner) (DHA1) family, major facilitator superfamily (MFS) || 1 0.25 -0.40 0.01 0.81 -0.58 0.44 -0.62 -0.80 0.32 -0.26 -0.61 -0.82 -0.56 -0.84 -0.43
8373 || orf19.4392 || DEM1 || || Putative mitochondrial exonuclease; alpha-factor induced || 1 0.33 -0.53 0.61 0.46 -0.24 -0.17 -0.44 -0.09 -0.14 -0.10 -0.16 -0.51 -0.55 -0.17 -0.94 -0.24
8374 || orf19.5388 || SWD1 || || Ortholog(s) have histone methyltransferase activity (H3-K4 specific) activity, role in chromatin silencing at telomere, histone H3-K4 methylation, telomere maintenance and Set1C/COMPASS complex, cytosol localization || 1 -0.20 -0.25 0.45 0.53 -0.41 -0.17 -0.52 -0.07 0.23 -0.23 -0.16 -0.38 -0.43 0.29 -0.72 -0.12
8375 || orf19.4410 || ALG1 || || Protein similar to S. cerevisiae Alg1p, a mannosyltransferase involved in N-linked protein glycosylation; likely to be essential for growth, based on an insertional mutagenesis strategy || 1 -0.16 -0.00 0.59 0.39 -0.05 -0.02 -0.12 -0.12 0.35 0.05 0.09 -0.06 -0.42 -0.08 -0.17 -0.16
8376 || orf19.4081 || || || Dubious open reading frame || 1 -0.46 -0.12 0.75 0.37 -0.29 0.49 -0.12 -0.56 0.12 -0.22 0.01 -0.43 -0.11 -0.26 -0.80 -0.41
8377 || orf19.6169 || ATO1 || || Putative fungal-specific transmembrane protein; induced by Rgt1; Spider biofilm induced || 1 -0.44 -0.04 1.27 1.26 -0.36 0.56 -0.17 -0.20 0.28 0.03 0.01 -0.36 -0.30 -0.52 -0.70 -0.64
8378 || orf19.3845 || FGR3 || || Protein lacking an ortholog in S. cerevisiae; transposon mutation affects filamentous growth || 1 -0.46 -0.21 0.59 0.71 0.06 0.09 -0.25 -0.30 -0.10 -0.21 -0.47 -0.23 -0.23 -0.29 0.01 -0.12
8379 || orf19.4949 || || || Ortholog of C. parapsilosis CDC317 : CPAR2_801735, C. dubliniensis CD36 : Cd36_84090, Candida orthopsilosis Co 90-125 : CORT_0B03960 and Spathaspora passalidarum NRRL Y-27907 : SPAPADRAFT_141253 || 1 -0.56 -0.41 0.88 0.83 -0.06 -0.08 -0.70 0.06 -0.01 -0.77 -0.46 -0.02 -0.43 -0.48 -0.45 -0.00
8380 || orf19.4949 || || || Ortholog of C. parapsilosis CDC317 : CPAR2_801735, C. dubliniensis CD36 : Cd36_84090, Candida orthopsilosis Co 90-125 : CORT_0B03960 and Spathaspora passalidarum NRRL Y-27907 : SPAPADRAFT_141253 || 1 -0.72 -0.77 0.94 0.77 -0.11 0.18 -0.61 -0.34 0.20 -0.13 -0.19 -0.23 -0.44 -0.29 -0.64 -0.22
8381 || orf19.1311 || SPO75 || || Ortholog(s) have role in ascospore wall assembly || 1 -0.47 -0.77 0.54 0.46 -0.43 -0.38 -0.41 -0.46 0.07 -0.22 0.23 -0.15 -0.50 -0.31 -0.45 -0.19
8382 || orf19.4733 || YMC2 || || Putative mitochondrial carrier protein; Gcn4-regulated; F-12/ CO2 early biofilm induced; Spider biofilm induced || 1 -0.19 -0.32 0.25 0.52 -0.03 -0.14 -0.41 -0.34 0.02 -0.32 0.15 0.21 -0.22 -0.58 -0.38 -0.41
8383 || orf19.7554 || || || Transporter; similar to the Sit1 siderophore transporter; induced by nitric oxide independent of Yhb1; repressed during chlamydospore formation in C. albicans and C. dubliniensis; rat catheter biofilm repressed || 1 -0.14 -0.10 0.38 1.31 0.08 0.18 -0.36 -0.05 -0.13 0.01 -0.23 0.14 -0.72 -0.40 -0.53 0.13
8384 || orf19.7554 || || || Transporter; similar to the Sit1 siderophore transporter; induced by nitric oxide independent of Yhb1; repressed during chlamydospore formation in C. albicans and C. dubliniensis; rat catheter biofilm repressed || 1 -0.44 -0.31 0.26 0.70 0.20 0.15 -0.31 -0.18 -0.04 0.28 -0.39 -0.12 -0.80 -0.23 -0.72 -0.05
8385 || orf19.7487 || || || Has domain(s) with predicted RNA binding, RNA-directed DNA polymerase activity and role in RNA-dependent DNA replication || 1 -0.70 -0.47 0.50 1.09 -0.01 0.05 -0.66 -0.53 -1.06 -0.31 -0.70 0.17 -0.76 0.21 -0.81 -0.18
8386 || orf19.3567 || BIO32 || || Putative class III aminotransferase with a predicted role in biotin biosynthesis; Spider biofilm induced || 1 -0.51 -0.45 0.55 0.32 -0.02 0.30 -0.08 -0.33 0.44 -0.68 -0.62 -0.29 0.10 0.05 -0.29 -0.11
8387 || orf19.3567 || BIO32 || || Putative class III aminotransferase with a predicted role in biotin biosynthesis; Spider biofilm induced || 1 -0.21 -0.43 0.54 0.56 -0.58 0.13 0.14 -0.20 0.67 -0.51 -0.51 0.03 0.10 -0.02 -0.29 -0.37
8388 || orf19.5023 || DAL7 || || Putative allantoate permease; mutant is viable || 1 -0.25 -0.18 0.58 0.25 -0.22 0.30 -0.34 -0.18 0.69 -0.29 -0.48 0.03 0.00 -0.25 -0.08 -0.33
8389 || orf19.2258 || || || Ortholog of C. dubliniensis CD36 : Cd36_21310, C. parapsilosis CDC317 : CPAR2_406650, Candida tenuis NRRL Y-1498 : CANTEDRAFT_130046 and Debaryomyces hansenii CBS767 : DEHA2F24134g || 1 -0.41 -0.01 0.65 0.46 0.23 0.71 -0.23 -0.62 0.44 0.08 -0.44 0.19 -0.09 -0.42 -0.65 -0.15
8390 || orf19.5820 || UGA6 || || Putative GABA-specific permease; decreased transcription is observed upon benomyl treatment or in an azole-resistant strain that overexpresses MDR1 || 1 -0.44 0.03 0.81 0.02 -0.16 1.10 -0.30 -0.74 0.88 0.02 -0.65 -0.16 0.24 -0.05 -0.83 -0.25
8391 || orf19.3373 || || || Putative protein of unknown function; transcript upregulated in clinical isolates from HIV+ patients with oral candidiasis; Spider biofilm induced || 1 -0.50 -0.07 1.18 0.14 -0.13 1.08 -0.66 -0.18 0.35 0.01 -1.20 -0.52 -0.14 -0.09 -1.02 -0.39
8392 || orf19.2064 || || || Putative transcription factor with zinc finger DNA-binding motif || 1 -0.29 0.22 0.56 0.43 -0.16 0.54 -0.24 -0.33 0.87 -0.30 -1.26 -0.47 -0.04 0.06 -0.86 0.09
8393 || orf19.5262 || || || Ortholog of C. dubliniensis CD36 : Cd36_11270 and Candida albicans WO-1 : CAWG_00238 || 1 -0.38 0.03 0.47 0.14 0.26 0.45 -0.74 -0.50 0.74 -0.16 -0.94 -0.11 0.25 -0.54 -1.08 0.10
8394 || orf19.2129 || || || Ortholog of S. cerevisiae Spo71; a meiosis-specific protein required for spore wall formation during sporulation in S. cerevisiae; possibly an essential gene, disruptants not obtained by UAU1 method || 1 -0.19 -0.16 0.41 0.16 -0.02 -0.02 -0.27 -0.13 0.32 -0.22 -0.24 -0.25 -0.26 -0.24 -0.40 -0.18
8395 || orf19.7158 || || || Protein of allantoate permease family; fungal-specific (no human or murine homolog); Hap43p-repressed gene || 1 -0.17 -0.26 0.84 0.50 -0.10 -0.04 -0.46 -0.19 0.89 -0.24 -0.92 -0.72 0.05 -0.05 -0.64 -0.56
8396 || orf19.4919 || || || Has domain(s) with predicted DNA binding, nucleic acid binding activity || 1 -0.34 -0.15 0.50 0.24 -0.18 0.22 -0.50 -0.30 0.10 -0.18 -0.58 -0.48 -0.10 -0.31 -0.26 -0.59
8397 || orf19.2745 || UME7 || || Putative transcription factor with zinc cluster DNA-binding motif; similar to S. cerevisiae Ume6p, which is a transcription factor involved in the regulation of meiotic genes || 1 -0.53 0.01 1.04 0.71 -0.36 0.41 -0.60 -0.70 0.87 -0.54 -0.73 -1.04 -0.13 -0.07 -1.04 -0.86
8398 || orf19.2429 || || || Protein of unknown function; induced by alpha pheromone in SpiderM medium || 1 -0.26 0.02 1.17 0.81 -0.32 0.35 -0.92 -0.69 0.06 -0.57 -1.05 -0.89 -0.24 0.05 -1.24 -0.81
8399 || orf19.690 || PLB2 || || Putative phospholipase B; conserved catalytic region; 6 putative N-glycosylation motifs; predicted secretion signal; no GPI anchor predicted; fungal-specific (no human or murine homolog) || 1 -0.22 -0.08 0.84 0.47 -0.18 0.30 -0.42 -0.61 0.09 -0.16 -0.63 -0.47 0.01 -0.47 -0.78 -0.14
8400 || orf19.2342 || SFT2 || || Putative membrane protein; transcript regulated by Mig1; Spider biofilm induced || 1 -0.25 0.11 0.39 0.53 0.11 -0.09 -0.43 -0.42 0.01 -0.40 -0.58 -0.10 0.22 -0.19 -0.27 -0.85
8401 || orf19.2423 || ZCF11 || || Zn(II)2Cys6 transcription factor; required for wild-type filamentous growth; mRNA binds She3 || 1 -0.37 0.02 0.38 0.78 -0.06 0.11 -0.40 -0.46 0.49 -0.31 -0.64 0.08 0.26 -0.25 -0.26 -1.12
8402 || orf19.7170 || || || Ortholog of C. dubliniensis CD36 : Cd36_73740, Candida tropicalis MYA-3404 : CTRG_05151 and Candida albicans WO-1 : CAWG_05736 || 1 -0.16 0.04 0.67 1.24 -0.13 0.29 -0.88 -0.62 1.05 -0.51 -1.02 -0.08 0.20 -0.79 -0.77 -1.06
8403 || orf19.4880 || || || Protein of unknown function; flow model biofilm induced || 1 -0.24 -0.06 0.41 0.36 0.19 0.07 -0.43 -0.48 0.48 -0.22 -0.39 -0.10 0.01 -0.40 -0.40 -0.50
8404 || orf19.6522 || || || Putative allantoate permease; Gcn4-regulated; Spider biofilm induced || 1 -0.47 -0.09 0.48 0.18 0.01 0.21 -0.50 -0.48 0.70 -0.34 -0.62 -0.26 0.38 -0.25 -0.45 -0.71
8405 || orf19.4549 || FGR38 || || Protein lacking an ortholog in S. cerevisiae; member of a family of related proteins; transposon mutation affects filamentous growth; macrophage-induced gene; Hap43p-repressed gene || 1 -0.38 -0.20 0.41 0.35 0.04 -0.01 -0.39 -0.38 0.42 -0.32 -0.56 -0.26 0.06 0.20 -0.44 -0.54
8406 || orf19.6009 || SET1 || || Lysine histone methyltransferase; methylates histone H3 K4; regulates of white-opaque switch, epithelial cell adhesion, agar-embedded filamentation, virulence in mice; unique N-terminus immunogenic in human; rat catheter biofilm repressed || 1 -0.40 -0.13 0.33 0.40 -0.01 0.25 -0.44 -0.42 0.40 -0.29 -0.43 0.18 0.15 0.13 -0.22 -0.56
8407 || orf19.6142 || || || Ortholog(s) have double-stranded DNA binding activity, role in reciprocal meiotic recombination and condensed nuclear chromosome localization || 1 -0.58 -0.19 0.61 0.46 -0.31 0.59 -0.54 -0.52 0.56 0.12 -0.46 -0.22 -0.05 -0.09 -0.74 -0.87
8408 || orf19.425 || || || Has domain(s) with predicted translation release factor activity and role in translational termination || 1 -0.37 -0.04 0.42 0.28 -0.17 0.20 -0.27 -0.40 0.35 0.19 -0.29 -0.20 0.34 0.05 -0.41 -0.38
8409 || orf19.3149 || LSP1 || || Eisosome component with a predicted role in endocytosis; protein present in exponential and stationary growth phase yeast cultures; caspofungin repressed; biofilm induced; fungal-specific (no human/murine homolog); sumoylation target || 1 -0.03 0.00 0.42 0.57 -0.58 0.11 -0.41 -0.45 0.07 -0.20 -0.57 -0.36 0.11 -0.16 -0.28 -0.90
8410 || orf19.3974 || PUT2 || || Putative delta-1-pyrroline-5-carboxylate dehydrogenase; alkaline upregulated; protein present in exponential and stationary growth phase yeast cultures; flow model biofilm induced; Spider biofilm induced || 1 -0.05 0.02 0.43 0.81 -0.01 -0.01 -0.74 -0.81 0.45 0.10 -0.70 -0.28 -0.01 0.22 -0.60 -0.59
8411 || orf19.5219 || IRA2 || || GTPase-activating protein; negatively regulates RAS by converting it from the GTP- to the GDP-bound inactive form; Spider biofilm induced; flow model biofilm repressed || 1 -0.09 -0.04 0.18 0.18 -0.00 -0.09 -0.54 -0.53 0.22 -0.16 -0.39 -0.13 -0.19 0.33 -0.25 -0.18
8412 || orf19.7158 || || || Protein of allantoate permease family; fungal-specific (no human or murine homolog); Hap43p-repressed gene || 1 -0.70 -0.22 0.71 0.56 -0.79 -0.22 -0.57 -0.91 0.79 -0.20 -1.18 -0.46 -0.50 0.52 -0.90 -0.75
8413 || orf19.6958 || ECM18 || || Ortholog(s) have mitochondrion localization || 1 -0.50 -0.24 0.58 0.41 -0.19 -0.26 -0.22 -0.24 0.27 0.01 -0.66 -0.57 0.04 0.56 -0.50 -0.47
8414 || orf19.2065 || || || Ortholog(s) have role in allantoin catabolic process and cytosol, nucleus localization || 1 -0.54 -0.41 0.36 0.17 -0.09 0.43 -0.30 -0.38 0.23 -0.07 -0.44 -0.22 -0.08 0.65 -0.57 -0.55
8415 || orf19.5874 || || || Ortholog of C. dubliniensis CD36 : Cd36_84250, C. parapsilosis CDC317 : CPAR2_806160, Candida tenuis NRRL Y-1498 : CANTEDRAFT_137075 and Debaryomyces hansenii CBS767 : DEHA2F11462g || 1 -0.51 -0.15 0.09 0.60 -0.21 0.50 -0.44 -0.32 0.20 0.04 -0.79 -0.57 -0.26 0.54 -0.47 -0.02
8416 || orf19.690 || PLB2 || || Putative phospholipase B; conserved catalytic region; 6 putative N-glycosylation motifs; predicted secretion signal; no GPI anchor predicted; fungal-specific (no human or murine homolog) || 1 -0.73 -0.36 0.10 0.12 -0.38 0.66 -0.72 -0.40 0.40 -0.09 -0.54 -0.44 0.02 0.31 -0.78 -0.30
8417 || orf19.4481 || MFALPHA || || Alpha factor mating pheromone precursor; three copies of pheromone that are proteolytically processed by Kex2p and possibly by Orf19.5851p; required for alpha cells to mate; expressed specifically in opaque phase MTLalpha/MTLalpha cells || 1 -0.81 -0.24 0.10 0.59 -0.95 0.42 -0.73 -0.72 0.67 0.24 -0.84 -0.38 -0.07 0.34 -1.47 -0.16
8418 || orf19.1249 || || || Ortholog(s) have 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino]imidazole-4-carboxamide isomerase activity, role in histidine biosynthetic process and cytosol, nucleus localization || 1 -0.49 -0.15 0.29 0.26 -0.44 0.11 -0.47 -0.45 0.24 0.37 -0.54 -0.28 -0.11 0.07 -0.52 -0.29
8419 || orf19.1989 || DCW1 || || Protein with predicted GPI modification; dfg5 dcw1 double mutant is inviable; not required for wild-type hyphal growth; upregulated in cyr1 mutant (yeast or hyphal form); Hap43-induced || 1 -0.50 -0.32 0.38 0.48 -0.57 0.07 -0.41 -0.05 -0.14 0.10 -0.58 -0.47 -0.14 -0.01 -0.75 -0.41
8420 || orf19.5616 || || || Ortholog of C. dubliniensis CD36 : Cd36_63740, C. parapsilosis CDC317 : CPAR2_503850, Pichia stipitis Pignal : PICST_32045 and Candida guilliermondii ATCC 6260 : PGUG_00070 || 1 -0.30 -0.08 0.71 0.84 -0.19 0.44 -0.74 -0.12 -0.18 0.06 -0.79 -0.45 -0.20 0.08 -0.57 -0.28
8421 || orf19.2633 || HGT14 || || Putative MFS glucose transporter; 20 member C. albicans glucose transporter family; 12 probable membrane-spanning segments; expressed in rich medium with 2% glucose; rat catheter and flow model biofilm induced || 1 -0.93 -0.86 0.52 0.53 -0.64 0.49 -0.81 -1.21 0.32 0.70 -2.47 -1.00 0.58 -0.26 -0.87 -1.64
8422 || orf19.7451 || FUN31 || || Putative PAS kinase involved in cell wall damage response; similar to S. cerevisiae Psk1p, a putative serine/threonine protein kinase; induced by Mnl1 under weak acid stress; rat catheter and Spider biofilm induced || 1 -0.18 -0.12 0.06 0.73 0.07 0.23 -0.21 -0.23 0.56 -0.11 -0.64 -0.24 -0.06 0.13 -0.22 -0.51
8423 || orf19.1078 || HBR2 || || Putative alanine glyoxylate aminotransferase; regulated by Gcn4p and hemoglobin; stationary phase enriched protein || 1 -0.17 -0.04 0.45 0.55 0.01 0.32 0.02 0.01 0.49 0.11 -0.39 -0.20 0.02 0.00 -0.78 -0.34
8424 || orf19.1459 || PPE1 || || Protein similar to S. cerevisiae Ppe1p; shows genetic interaction with some genes involved in diploid filamentous growth and haploid invasive growth in S. cerevisiae || 1 -0.22 -0.02 0.48 0.51 -0.40 0.54 -0.24 0.01 0.44 0.04 -0.24 0.03 -0.67 -0.16 -0.72 0.19
8425 || orf19.6188 || || || Putative adhesin-like protein || 1 0.24 -0.31 0.38 0.72 -0.37 1.07 -0.78 -0.62 1.10 -0.37 -0.79 -0.68 0.04 -1.32 0.00
8426 || orf19.4149 || || || Predicted protein of unknown function; overlaps orf19.4149.1 || 1 -0.51 -0.31 0.71 -0.01 -0.57 0.95 -0.85 -0.89 0.79 -0.47 -0.69 0.59 -0.36 0.03 -0.68 0.07
8427 || orf19.4949 || || || Ortholog of C. parapsilosis CDC317 : CPAR2_801735, C. dubliniensis CD36 : Cd36_84090, Candida orthopsilosis Co 90-125 : CORT_0B03960 and Spathaspora passalidarum NRRL Y-27907 : SPAPADRAFT_141253 || 1 -0.66 -0.43 0.57 -0.04 -0.44 0.45 -0.56 -0.15 0.59 -0.08 -0.27 -0.19 -0.65 0.32 -0.39 -0.15
8428 || orf19.6141 || HGT16 || || Putative glucose transporter of the major facilitator superfamily; the C. albicans glucose transporter family comprises 20 members; 12 probable membrane-spanning segments; gene has intron; expressed in rich medium with 2% glucose || 1 -0.82 -1.18 0.85 0.14 -0.72 0.06 -0.29 -0.38 0.14 0.37 -0.94 -0.85 -0.86 -0.02 -0.11 -0.74
8429 || orf19.721 || || || Ortholog(s) have polynucleotide 5'-hydroxyl-kinase activity || 1 0.22 0.05 0.38 0.12 -0.17 0.13 -0.48 -0.45 -0.20 0.34 -0.55 0.04 0.05 -0.07 -0.09 -0.09
8430 || orf19.600 || TRK1 || || Potassium transporter; mediates K+ and Cl- influx; role in sensitivity to cationic antimicrobial peptides, not by direct uptake, possibly related to membrane permeability; contains 5' UTR intron; Spider biofilm induced || 1 0.08 0.08 0.26 0.13 0.60 0.51 -0.79 -0.80 -0.46 0.54 -0.98 -0.53 -0.22 -0.10 -0.01 -0.10
8431 || orf19.4991 || MPT5 || || Putative RNA-binding protein; Hap43p-repressed gene; protein induced during the mating process || 1 0.14 0.18 0.33 0.25 0.12 0.13 -0.35 -0.33 0.03 0.33 -0.81 -0.45 0.05 0.23 0.43 -0.39
8432 || orf19.2117 || LEU5 || || Putative mitochondrial carrier protein; Hap43-repressed; rat catheter biofilm induced || 1 -0.03 -0.10 0.40 0.41 -0.02 0.25 -0.40 -0.52 0.13 0.76 -0.86 0.05 -0.12 -0.25 0.37 -0.44
8433 || orf19.168 || || || Ortholog(s) have role in U4 snRNA 3'-end processing, exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA and LSU-rRNA), more || 1 -0.10 0.04 0.51 0.56 -0.02 0.81 -0.13 -0.25 -0.24 0.28 -0.70 -0.05 -0.02 0.02 0.50 -0.66
8434 || orf19.966 || DUS4 || || Ortholog(s) have tRNA dihydrouridine synthase activity, role in tRNA modification and mitochondrion localization || 1 -0.02 -0.09 0.38 0.16 -0.07 0.81 0.02 -0.48 -0.54 -0.03 -0.71 -0.21 -0.28 0.07 -0.12 -0.21
8435 || orf19.1318 || || || Ortholog of C. dubliniensis CD36 : Cd36_43350, C. parapsilosis CDC317 : CPAR2_403560, Debaryomyces hansenii CBS767 : DEHA2A08250g and Pichia stipitis Pignal : PICST_29838 || 1 0.28 0.11 0.54 0.17 0.01 0.49 -0.33 -0.47 -0.15 0.06 -0.44 0.16 0.08 0.32 0.09 -0.20
8436 || orf19.1318 || || || Ortholog of C. dubliniensis CD36 : Cd36_43350, C. parapsilosis CDC317 : CPAR2_403560, Debaryomyces hansenii CBS767 : DEHA2A08250g and Pichia stipitis Pignal : PICST_29838 || 1 0.29 0.23 0.45 0.10 0.14 0.24 -0.31 -0.28 -0.23 -0.08 -0.35 0.00 0.05 0.29 -0.09 -0.39
8437 || orf19.5220 || || || Putative RNA exonuclease; induced in a ssr1 null mutant || 1 0.62 0.48 0.37 0.56 0.07 0.81 -0.45 -0.30 -0.88 0.29 -0.66 0.21 0.09 0.64 -0.54 -0.30
8438 || orf19.2883 || CSO99 || || Protein of unknown function; Hap43-repressed gene; protein not conserved in S. cerevisiae || 1 0.90 0.84 0.25 0.59 -0.58 -0.09 -0.45 -0.40 -0.12 -0.67 -0.61 0.27 0.57 -1.15 -0.95 -0.03
8439 || orf19.2883 || CSO99 || || Protein of unknown function; Hap43-repressed gene; protein not conserved in S. cerevisiae || 1 0.76 0.75 0.08 0.25 -0.62 -0.30 -0.41 -0.52 -0.42 -0.71 -1.10 0.07 0.53 -1.12 -0.94 -0.58
8440 || orf19.5461 || || || Ortholog of Candida albicans WO-1 : CAWG_02350 || 1 0.50 0.96 0.50 0.43 -0.52 0.20 -0.52 -0.15 -0.33 -0.28 -0.47 -0.05 0.06 -0.92 -0.24 -0.66
8441 || orf19.6257 || GLT1 || || Putative glutamate synthase; regulated by Sef1, Sfu1, and Hap43; rat catheter biofilm repressed || 1 0.50 0.73 0.40 0.79 -1.56 -0.53 -0.33 -0.51 -0.08 0.03 -0.67 0.23 0.15 -1.42 -0.35 -0.80
8442 || orf19.726 || PPZ1 || || Protein phosphatase Z; type 1 family serine/threonine specific protein phosphatase involved in cation homeostasis and cell wall integrity || 1 0.18 -0.09 0.45 0.28 0.03 0.15 -0.43 -0.04 -0.17 -0.34 -0.15 -0.14 0.14 -0.19 0.49 -0.44
8443 || orf19.3267 || || || Ortholog(s) have palmitoyltransferase activity and role in ascospore wall assembly, cortical actin cytoskeleton organization, establishment of cell polarity, protein palmitoylation, regulation of exocytosis, vacuole fusion, non-autophagic || 1 0.04 0.11 0.57 0.29 0.05 -0.02 -0.44 -0.19 0.09 -0.25 0.03 -0.36 0.32 0.04 0.21 -0.21
8444 || orf19.4166 || ZCF21 || || Predicted Zn(II)2Cys6 transcription factor; mutants display increased colonization of mouse kidneys; Spider biofilm induced || 1 -0.29 -0.25 -0.16 -0.01 0.43 0.40 -0.23 -0.56 -0.50 -0.19 -0.70 0.02 0.22 -0.03 1.12 0.25
8445 || orf19.3439 || || || Protein of unknown function; Cyr1-repressed; rat catheter and Spider biofilm induced || 1 -0.81 -0.85 -0.03 0.72 0.12 1.47 -0.49 -1.69 -0.67 0.22 -1.74 0.19 1.30 1.01 2.57 -0.31
8446 || orf19.3439 || || || Protein of unknown function; Cyr1-repressed; rat catheter and Spider biofilm induced || 1 -0.77 -0.88 -0.38 0.88 -0.20 1.31 -0.54 -2.53 -0.77 0.07 -2.27 0.35 0.79 0.45 2.66 -1.45
8447 || orf19.3439 || || || Protein of unknown function; Cyr1-repressed; rat catheter and Spider biofilm induced || 1 -0.84 -0.89 -0.48 0.60 0.52 1.23 -0.89 -2.26 -1.35 -0.21 -2.35 -0.13 0.77 0.78 2.00 -0.74
8448 || orf19.3439 || || || Protein of unknown function; Cyr1-repressed; rat catheter and Spider biofilm induced || 1 -0.75 -0.64 -0.68 0.31 0.47 1.14 -0.80 -2.12 -1.20 -0.13 -1.97 -0.14 0.81 0.92 1.81 -0.83
8449 || orf19.3439 || || || Protein of unknown function; Cyr1-repressed; rat catheter and Spider biofilm induced || 1 -0.72 -0.60 -0.54 0.35 0.55 1.20 -0.90 -2.31 -1.42 -0.34 -2.24 -0.02 0.73 0.92 1.87 -1.05
8450 || orf19.3674 || GAL102 || || UDP-glucose 4,6-dehydratase; role in mannosylation of cell wall proteins; mutation confers hypersensitivity to toxic ergosterol analog; overlaps orf19.3673; Spider biofilm induced || 1 -1.08 -0.62 -0.39 0.21 0.61 1.48 -1.34 -1.15 -1.14 -0.21 -1.38 -1.16 0.73 1.45 2.38 -0.92
8451 || orf19.6578 || || || Predicted membrane transporter; vesicular neurotransmitter (VNT) family, major facilitator superfamily (MFS); repressed in core caspofungin response; induced in oralpharyngeal candidasis; Spider biofilm induced || 1 -0.47 -0.46 0.22 0.24 -0.20 0.40 -0.45 -0.87 -0.24 0.56 -0.89 -0.15 -0.36 0.09 1.07 -0.27
8452 || orf19.5962 || HGT4 || || Glucose and galactose sensor; fermentation, filamentation, virulence roles; 20-member glucose transporter family; extended C terminus; high-glucose repressed; macrophage induced; flow model biofilm repressed; Spider biofilm induced || 1 -0.17 -0.25 -0.02 0.38 0.41 0.43 -0.41 -0.62 -0.27 -0.06 -0.38 -0.15 0.18 -0.08 0.12 -0.40
8453 || orf19.1363 || || || Putative protein of unknown function; Plc1-regulated; transcript induced by Mnl1 under weak acid stress; flow model, rat catheter, Spider biofilm induced || 1 -0.96 -0.68 0.58 1.23 -0.07 0.75 1.00 -1.31 -0.31 -0.26 -2.33 -1.03 0.48 0.85 -0.25 -0.85
8454 || orf19.1363 || || || Putative protein of unknown function; Plc1-regulated; transcript induced by Mnl1 under weak acid stress; flow model, rat catheter, Spider biofilm induced || 1 -0.70 -0.67 1.11 0.67 0.37 1.29 0.61 -1.49 -0.04 -0.45 -1.74 -1.18 0.45 0.97 0.16 -1.06
8455 || orf19.1363 || || || Putative protein of unknown function; Plc1-regulated; transcript induced by Mnl1 under weak acid stress; flow model, rat catheter, Spider biofilm induced || 1 -1.12 -0.91 -0.38 0.12 0.92 1.29 1.28 -2.10 -0.33 -0.43 -2.61 -1.45 0.86 1.06 0.74 -2.04
8456 || orf19.1363 || || || Putative protein of unknown function; Plc1-regulated; transcript induced by Mnl1 under weak acid stress; flow model, rat catheter, Spider biofilm induced || 1 -1.39 -1.21 -0.33 0.08 0.55 1.60 0.93 -2.94 -0.99 -1.26 -3.14 -2.01 0.51 0.86 0.37 -1.92
8457 || orf19.1363 || || || Putative protein of unknown function; Plc1-regulated; transcript induced by Mnl1 under weak acid stress; flow model, rat catheter, Spider biofilm induced || 1 -0.76 -1.13 -0.43 0.31 1.05 2.45 1.42 -2.47 -1.28 -0.83 -2.65 -0.99 0.77 1.22 1.05 -0.67
8458 || orf19.6514 || CUP9 || || Transcription factor; upregulated in clinical strains from HIV patients with oral candidiasis; yeast-hypha switch repressed; ketoconazole-induced; Plc1-regulated; colony morphology-related Ssn6 regulation; Spider, flow model biofilm induced || 1 -0.67 -0.70 0.38 0.90 0.75 1.51 -0.15 -2.37 -1.53 -1.74 -2.83 -2.87 0.34 0.36 1.05 -0.80
8459 || orf19.6514 || CUP9 || || Transcription factor; upregulated in clinical strains from HIV patients with oral candidiasis; yeast-hypha switch repressed; ketoconazole-induced; Plc1-regulated; colony morphology-related Ssn6 regulation; Spider, flow model biofilm induced || 1 -1.29 -1.22 0.39 0.75 0.61 1.69 -0.50 -3.24 -1.47 -1.48 -3.98 -3.49 -0.04 1.01 0.85 -1.10
8460 || orf19.5867 || WSC1 || || Putative cell wall component; transcript upregulated in cyr1 mutant (yeast or hyphae); Spider and flow model biofilm induced || 1 -0.41 -0.42 -0.48 -0.61 0.30 -0.34 -0.01 -0.72 -0.01 -0.16 -1.02 -0.72 0.18 -0.06 -0.09 -0.95
8461 || orf19.1488 || || || Ortholog of C. dubliniensis CD36 : Cd36_16630, C. parapsilosis CDC317 : CPAR2_210300, Candida tenuis NRRL Y-1498 : CANTEDRAFT_116870 and Debaryomyces hansenii CBS767 : DEHA2B04334g || 1 -0.33 -0.38 -0.74 -0.55 0.12 0.17 -0.09 -0.55 -0.32 -0.10 -0.37 -0.57 0.53 0.24 0.31 -0.46
8462 || orf19.3507 || MCR1 || || NADH-cytochrome-b5 reductase; soluble in hyphae; alkaline downregulated; farnesol, ketoconazole or flucytosine induced; protein present in exponential and stationary growth phase yeast; YNB biofilm induced; rat catheter biofilm repressed || 1 -0.31 -0.15 -0.27 -0.38 -0.03 0.42 -0.33 -0.41 -0.05 -0.10 -0.46 -0.47 0.11 -0.02 0.31 -0.36
8463 || orf19.4530.1 || || || Protein of unknown function; regulated by Nrg1, Tup1; Spider and flow model biofilm induced || 1 -1.07 -1.13 -1.11 -1.22 0.60 0.92 -0.25 -0.78 -0.34 -1.36 -2.80 -2.37 1.13 -0.27 0.55 -1.84
8464 || orf19.4530.1 || || || Protein of unknown function; regulated by Nrg1, Tup1; Spider and flow model biofilm induced || 1 -0.85 -0.95 -0.82 -0.96 0.95 1.44 -0.00 -0.55 0.19 -0.90 -2.44 -1.68 1.15 0.29 0.90 -1.20
8465 || orf19.6608 || || || Predicted DDE superfamily endonuclease domain; repression correlates with clinical development of fluconazole resistance; Spider biofilm induced || 1 -0.24 -0.15 -0.31 -0.69 -0.00 0.23 0.31 -0.16 -0.12 -0.34 -0.79 -1.30 0.70 0.55 0.61 -0.52
8466 || orf19.2024 || || || Ortholog of Candida albicans WO-1 : CAWG_03878 || 1 0.29 0.04 0.30 0.07 -0.14 0.25 0.02 -0.09 0.04 -0.34 -0.95 -1.36 0.37 0.58 0.02 -0.35
8467 || orf19.2024 || || || Ortholog of Candida albicans WO-1 : CAWG_03878 || 1 -0.05 -0.67 0.02 -0.03 0.04 0.67 -0.64 -0.45 0.02 -0.39 -1.08 -1.98 0.21 1.51 -0.40 -0.26
8468 || orf19.4328 || CCC2 || || Copper-transporting P-type ATPase of Golgi; required for wild-type iron assimilation (indirect effect via Fet3p); induced by iron starvation, ciclopirox olamine; caspofungin repressed; not required for virulence in mouse systemic infection || 1 -0.08 0.01 0.22 -0.02 -0.02 0.23 -0.77 -0.91 -0.73 -0.32 -0.94 -1.14 0.56 1.08 -0.18 -0.10
8469 || orf19.1080 || || || Ortholog of C. dubliniensis CD36 : Cd36_64900, C. parapsilosis CDC317 : CPAR2_600390, Pichia stipitis Pignal : PICST_30726 and Candida guilliermondii ATCC 6260 : PGUG_04023 || 1 -0.20 -0.36 0.04 -0.03 -0.44 0.86 -0.73 -1.12 -0.23 0.14 -1.27 -0.96 0.98 1.36 -0.23 -0.26
8470 || orf19.1488 || || || Ortholog of C. dubliniensis CD36 : Cd36_16630, C. parapsilosis CDC317 : CPAR2_210300, Candida tenuis NRRL Y-1498 : CANTEDRAFT_116870 and Debaryomyces hansenii CBS767 : DEHA2B04334g || 1 -0.44 -0.32 -0.17 -0.21 -0.14 0.33 -0.39 -0.75 0.05 0.46 -0.91 -0.24 0.38 0.67 0.01 -0.23
8471 || orf19.4875 || || || Ortholog(s) have role in mRNA splicing, via spliceosome and U2-type spliceosomal complex localization || 1 0.32 -0.21 -0.20 0.26 -0.00 0.82 -0.48 -0.99 0.32 0.30 -0.87 -0.09 0.15 0.78 -0.33 -0.03
8472 || orf19.5001 || CUP2 || || Putative copper-binding transcription factor; required for normal resistance to copper; activates transcription of metallothionein genes; Hap43-repressed; Spider biofilm induced || 1 0.04 -0.01 0.12 -0.09 -0.17 0.02 -0.02 -0.52 -0.17 0.05 -0.44 -0.13 0.37 0.05 -0.21 -0.33
8473 || orf19.1080 || || || Ortholog of C. dubliniensis CD36 : Cd36_64900, C. parapsilosis CDC317 : CPAR2_600390, Pichia stipitis Pignal : PICST_30726 and Candida guilliermondii ATCC 6260 : PGUG_04023 || 1 -0.47 -0.48 -0.08 -0.05 -0.38 0.69 -0.83 -0.95 -0.53 -0.44 -2.43 -1.09 1.57 0.04 -0.72 -1.12
8474 || orf19.5170 || ENA21 || || Predicted P-type ATPase sodium pump; Gcn4p-regulated; flucytosine, amphotericin B, or ketoconazole-induced; osmotic stress-induced; overlaps orf19.5170.1, which is annotated as a blocked reading frame; Spider biofilm induced || 1 -0.54 -0.44 -0.22 -0.02 -0.28 0.20 -0.60 -0.94 -0.57 -0.58 -1.10 -0.36 0.35 0.49 -0.13 -0.95
8475 || orf19.5170 || ENA21 || || Predicted P-type ATPase sodium pump; Gcn4p-regulated; flucytosine, amphotericin B, or ketoconazole-induced; osmotic stress-induced; overlaps orf19.5170.1, which is annotated as a blocked reading frame; Spider biofilm induced || 1 -0.45 -0.57 -0.13 0.23 -0.28 0.27 -0.63 -0.83 -0.48 -0.28 -1.03 -0.15 0.82 0.50 0.21 -1.03
8476 || orf19.5926 || ARG11 || || Putative ornithine transporter of the mitochondrial inner membrane; induced during the mating process || 1 -0.51 -0.38 0.27 0.53 -0.81 -0.04 0.17 -1.09 -0.46 -0.27 -1.73 -0.09 1.14 0.45 0.26 -0.94
8477 || orf19.4788 || ARG5,6 || || Arginine biosynthetic enzyme; processed in S. cerevisiae into 2 polypeptides with acetylglutamate kinase (Arg6) activity and acetylglutamate-phosphate reductase (Arg5) activity; Gcn4 regulated; alkaline repressed; Spider biofilm induced || 1 -0.77 -0.87 0.02 0.45 -1.19 0.06 -0.59 -1.68 -0.75 -0.95 -2.08 -0.63 1.01 -0.49 0.19 -0.39
8478 || orf19.4788 || ARG5,6 || || Arginine biosynthetic enzyme; processed in S. cerevisiae into 2 polypeptides with acetylglutamate kinase (Arg6) activity and acetylglutamate-phosphate reductase (Arg5) activity; Gcn4 regulated; alkaline repressed; Spider biofilm induced || 1 -0.83 -0.95 0.39 0.74 -1.85 -0.05 -0.55 -1.61 -0.54 -1.08 -2.40 -1.06 1.01 -0.31 -0.16 -0.94
8479 || orf19.7469 || ARG1 || || Argininosuccinate synthase; arginine synthesis; Gcn4, Rim101 regulated; induced by amino acid starvation (3-AT), benomyl treatment; stationary phase enriched protein; repressed in alkalinizing medium; rat catheter, Spider biofilm induced || 1 -0.74 -0.83 0.50 0.35 -1.06 0.78 -0.12 -1.00 0.47 -0.63 -1.33 -0.49 1.48 -0.42 0.29 -1.20
8480 || orf19.7469 || ARG1 || || Argininosuccinate synthase; arginine synthesis; Gcn4, Rim101 regulated; induced by amino acid starvation (3-AT), benomyl treatment; stationary phase enriched protein; repressed in alkalinizing medium; rat catheter, Spider biofilm induced || 1 -0.74 -0.87 0.76 0.89 -1.60 1.00 -0.01 -1.75 0.54 -0.73 -2.29 -0.77 1.99 -0.71 0.14 -1.51
8481 || orf19.7469 || ARG1 || || Argininosuccinate synthase; arginine synthesis; Gcn4, Rim101 regulated; induced by amino acid starvation (3-AT), benomyl treatment; stationary phase enriched protein; repressed in alkalinizing medium; rat catheter, Spider biofilm induced || 1 -0.98 -1.13 0.38 0.81 -1.88 1.02 -0.14 -1.98 0.39 -0.59 -2.67 -0.61 1.92 -0.64 0.42 -1.38
8482 || orf19.7469 || ARG1 || || Argininosuccinate synthase; arginine synthesis; Gcn4, Rim101 regulated; induced by amino acid starvation (3-AT), benomyl treatment; stationary phase enriched protein; repressed in alkalinizing medium; rat catheter, Spider biofilm induced || 1 -1.03 -0.96 0.41 0.45 -1.64 0.88 -0.23 -1.83 0.34 -0.88 -2.44 -0.76 1.65 -0.57 0.36 -1.39
8483 || orf19.7469 || ARG1 || || Argininosuccinate synthase; arginine synthesis; Gcn4, Rim101 regulated; induced by amino acid starvation (3-AT), benomyl treatment; stationary phase enriched protein; repressed in alkalinizing medium; rat catheter, Spider biofilm induced || 1 -0.94 -0.99 0.35 0.80 -1.44 1.09 -0.00 -1.73 0.27 -0.81 -2.53 -0.42 1.96 -0.76 0.61 -0.87
8484 || orf19.4630 || CPA1 || || Putative carbamoyl-phosphate synthase subunit; alkaline repressed; rat catheter, Spider and flow model biofilm induced || 1 -0.34 -0.42 0.42 0.49 -0.86 1.27 -0.34 -2.50 -0.08 -1.51 -2.76 -1.08 1.35 -0.90 0.02 -1.41
8485 || orf19.4630 || CPA1 || || Putative carbamoyl-phosphate synthase subunit; alkaline repressed; rat catheter, Spider and flow model biofilm induced || 1 -0.01 -0.04 1.09 0.88 -0.51 1.43 -0.15 -1.59 0.40 -1.12 -2.37 -1.08 1.56 -0.68 0.21 -1.40
8486 || orf19.5610 || ARG3 || || Putative ornithine carbamoyltransferase; Gcn4-regulated; Hap43-induced; repressed in alkalinizing medium; rat catheter and Spider biofilm induced || 1 -0.04 -0.14 0.92 0.78 -0.63 1.59 -0.31 -1.73 0.28 -0.94 -2.24 -1.37 1.34 0.19 0.44 -0.67
8487 || orf19.3770 || ARG8 || || Putative acetylornithine aminotransferase; Gcn2, Gcn4 regulated; rat catheter biofilm induced; Spider biofilm induced || 1 -0.53 -0.54 0.16 0.15 -0.24 0.74 0.45 -1.19 0.46 -1.19 -1.37 -0.10 0.88 -0.41 0.12 -0.04
8488 || orf19.3770 || ARG8 || || Putative acetylornithine aminotransferase; Gcn2, Gcn4 regulated; rat catheter biofilm induced; Spider biofilm induced || 1 -0.40 -0.33 0.34 0.53 -0.30 0.72 0.38 -0.99 0.93 -0.96 -1.02 0.13 0.89 -0.20 0.22 -0.05
8489 || orf19.6689 || ARG4 || || Argininosuccinate lyase, catalyzes the final step in the arginine biosynthesis pathway; alkaline downregulated; flow model biofilm induced; Spider biofilm induced || 1 -0.40 -0.45 0.13 0.34 -1.12 0.75 0.06 -1.20 0.54 -0.40 -1.13 0.38 1.22 -0.31 -0.10 -0.14
8490 || orf19.6689 || ARG4 || || Argininosuccinate lyase, catalyzes the final step in the arginine biosynthesis pathway; alkaline downregulated; flow model biofilm induced; Spider biofilm induced || 1 -0.18 -0.14 0.43 0.32 -0.31 0.47 -0.15 -0.80 0.55 -0.47 -0.74 -0.09 0.74 -0.67 -0.28 -0.29
8491 || orf19.3221 || CPA2 || || Putative arginine-specific carbamoylphosphate synthetase; protein enriched in stationary phase yeast cultures; rat catheter biofilm induced; Spider biofilm induced || 1 -0.46 -0.14 1.11 0.82 -0.89 0.23 -0.20 -0.72 0.64 -0.07 -1.04 -0.13 1.51 -0.27 -0.09 -0.28
8492 || orf19.3221 || CPA2 || || Putative arginine-specific carbamoylphosphate synthetase; protein enriched in stationary phase yeast cultures; rat catheter biofilm induced; Spider biofilm induced || 1 -0.81 -0.69 0.75 1.21 -1.77 -0.01 -0.50 -1.16 -0.12 -0.07 -1.97 -0.18 1.57 -0.12 -0.28 -0.53
8493 || orf19.6224 || || || RTA domain protein; predicted role in response to stress; Spider biofilm induced || 1 -0.89 -0.99 0.44 1.71 -1.65 -0.91 -0.71 -1.47 0.55 -0.38 -2.60 -1.39 1.66 0.13 -1.30 -0.32
8494 || orf19.5610 || ARG3 || || Putative ornithine carbamoyltransferase; Gcn4-regulated; Hap43-induced; repressed in alkalinizing medium; rat catheter and Spider biofilm induced || 1 0.07 0.16 0.82 0.96 -0.57 1.27 -0.40 -1.03 0.46 -0.64 -1.47 -0.85 1.06 -0.23 0.15 0.04
8495 || orf19.3986 || PPR1 || || Putative transcription factor with zinc cluster DNA-binding motif; has similarity to S. cerevisiae Ppr1p, which is a transcription factor involved in the regulation of uracil biosynthesis genes || 1 -0.06 0.23 0.35 0.11 -0.21 0.09 -0.02 -0.09 0.02 -0.31 -0.69 -0.01 0.31 0.03 -0.13 -0.12
8496 || orf19.3507 || MCR1 || || NADH-cytochrome-b5 reductase; soluble in hyphae; alkaline downregulated; farnesol, ketoconazole or flucytosine induced; protein present in exponential and stationary growth phase yeast; YNB biofilm induced; rat catheter biofilm repressed || 1 0.04 -0.03 -0.04 0.20 -0.63 0.12 0.02 -0.04 0.13 -0.01 -0.74 -0.34 0.27 0.20 0.04 -0.48
8497 || orf19.6605 || || || Ortholog(s) have fungal-type vacuole, mitochondrion localization || 1 -0.18 -0.30 -0.23 -0.19 -0.68 -0.79 -0.41 -0.19 -0.10 0.27 -1.26 -0.47 -0.95 -0.03 0.54 -0.41
8498 || orf19.4948 || REX3 || || Ortholog(s) have 3'-5'-exoribonuclease activity and role in U5 snRNA 3'-end processing, exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) || 1 -0.19 0.09 0.09 0.00 -0.28 -0.03 -0.03 0.02 -0.21 0.05 -0.37 -0.30 -0.17 -0.07 0.07 -0.22
8499 || orf19.3637 || || || Dubious open reading frame || 1 -0.82 0.06 -0.36 -0.69 -0.35 -0.13 -0.16 -0.34 0.18 -0.48 0.01 -0.71
8500 || orf19.5236.1 || || || ORF Predicted by Annotation Working Group; merged with orf19.5236 in Assembly 21 || 1 -0.34 -0.39 -0.29 -0.46 -0.02 -0.16 -0.58 -0.29 0.26 -0.07 -0.56 -0.80 0.02 -0.18 -0.83 0.05
8501 || orf19.3199 || PIKA || || Putative phosphatidylinositol kinase; non-sex gene located within the MTLa mating-type-like locus || 1 0.04 -0.07 -0.35 -0.90 -0.31 -0.20 -0.07 -0.18 -0.16 -0.68 -0.31 -0.50 -0.45 -0.26 -0.54 0.12
8502 || orf19.4984 || || || Has domain(s) with predicted chitin binding, chitinase activity and role in carbohydrate metabolic process, cell wall macromolecule catabolic process, chitin catabolic process || 1 -0.42 -0.26 -0.14 -0.49 -0.03 -0.14 -0.28 -0.18 0.30 -0.56 -0.23 -0.23 -0.34 -0.31 -0.67 -0.03
8503 || orf19.5300 || || || Calnexin; integral membrane ER chaperone involved in folding and quality control of glycoproteins; caspofungin induced || 1 -0.20 -0.29 -0.27 -0.23 -0.36 -0.39 -0.28 -0.09 0.15 -0.50 -0.04 -0.26 -0.25 -0.62 -0.25 -0.05
8504 || orf19.5033 || || || Ortholog(s) have Atg8 ligase activity, protein tag activity || 1 -0.29 -0.08 -0.78 -0.79 0.05 -0.19 -0.31 0.00 0.14 -0.27 -0.16 -0.01 -0.11 -0.14 0.16 -0.28
8505 || orf19.230 || || || Ortholog of S. cerevisiae Pet111; a mitochondrial translational activator specific for the COX2 mRNA; Hap43-induced gene || 1 -0.68 -0.26 -1.84 -2.26 0.20 -1.19 -0.68 -1.06 -0.16 -0.82 -0.64 -0.35 0.16 -1.00 -0.09 -0.94
8506 || orf19.6885 || SPO7 || || Putative regulatory subunit of Nem1-Spo7 phosphatase holoenzyme that regulates nuclear growth by controling phospholipid biosynthesis; induced by alpha pheromone in SpiderM medium || 1 -0.86 -0.81 -1.05 -0.80 -0.40 -0.44 -0.43 -0.48 -0.20 0.03 -0.14 0.15 0.26 -0.46 0.32 -0.63
8507 || orf19.451 || SOK1 || || Protein kinase: mutants are sensitive to growth on hydrogen peroxide medium; induced by alpha pheromone in SpiderM medium; rat catheter and Spider biofilm induced || 1 -0.28 -0.29 -0.84 -0.81 -0.39 -0.32 0.31 -0.87 -0.33 -0.45 -0.61 -0.22 0.17 -0.43 0.10 -0.44
8508 || orf19.451 || SOK1 || || Protein kinase: mutants are sensitive to growth on hydrogen peroxide medium; induced by alpha pheromone in SpiderM medium; rat catheter and Spider biofilm induced || 1 -0.43 -0.36 -0.34 -0.64 -0.53 -0.15 0.03 -0.85 -0.34 -0.57 -0.70 -0.47 -0.13 -0.45 0.01 -0.47
8509 || orf19.5006.1 || || || Ortholog(s) have SNAP receptor activity and role in Golgi to plasma membrane transport, cytokinesis, endocytosis, exocytosis, vesicle fusion || 1 -0.18 -0.33 -0.34 -0.53 -0.40 -0.17 -0.77 -0.71 -0.66 -0.69 -0.90 -0.80 -0.56 -0.10 -0.37 -0.77
8510 || orf19.3689 || || || Putative protein similar to 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase; expression downregulated in an ssr1 null mutant || 1 -0.21 0.00 -0.50 -0.35 0.07 -0.37 -0.59 -0.51 -0.58 -0.44 -0.62 -0.60 -0.22 -0.34 -0.12 -0.57
8511 || orf19.138 || FIG1 || || S. cerevisiae Fig1 ortholog; an integral membrane protein required for mating; role in thigmotropism; transcript is opaque-specific and a-specific; activated by Cph1 or alpha pheromone || 1 -0.38 -0.32 -0.71 -0.18 -0.17 -0.58 -0.74 -0.21 -0.18 -0.86 -0.14 -0.54 -0.14 -0.37 -0.57 -0.62
8512 || orf19.1630 || || || Ortholog(s) have cytoplasm localization || 1 -0.11 -0.15 -0.50 -0.36 -0.31 -0.43 -0.28 0.01 -0.45 -0.54 -0.20 -0.42 -0.22 -0.43 -0.29 -0.40
8513 || orf19.4035 || PGA4 || || GPI-anchored cell surface protein; beta-1,3-glucanosyltransferase with similarity to the A. fumigatus GEL family; transcript induced in RHE model of oral candidiasis; fluconazol-induced || 1 -0.28 -0.11 -0.97 -0.14 -0.44 -0.80 -0.46 -0.35 -0.60 -0.73 -0.75 -0.40 0.23 -0.52 -0.62 -0.71
8514 || orf19.607 || || || Protein involved in transcription-coupled nucleotide excision repair of UV-induced DNA lesions; Spider biofilm induced || 1 -0.31 -0.09 -0.71 -0.50 -0.56 -0.75 -0.84 -1.15 -1.04 -1.22 -0.95 -1.67 -0.02 -1.36 -0.87 -1.42
8515 || orf19.50 || || || Ortholog(s) have role in SCF-dependent proteasomal ubiquitin-dependent protein catabolic process, cellular response to DNA damage stimulus, cellular response to methylmercury and SCF ubiquitin ligase complex, cytosol, nucleus localization || 1 -0.40 -0.64 -0.72 -0.80 -0.64 0.13 -0.68 -1.19 -1.29 -1.21 -0.65 -1.29 -0.35 -1.24 -0.83 -0.66
8516 || orf19.7433 || || || Ortholog(s) have nucleocytoplasmic transporter activity, structural constituent of nuclear pore activity || 1 -0.09 -0.16 -0.67 -0.38 0.11 -0.06 -0.14 -0.44 -0.67 -0.58 -0.34 -0.72 -0.27 -0.82 -0.33 -0.47
8517 || orf19.7433 || || || Ortholog(s) have nucleocytoplasmic transporter activity, structural constituent of nuclear pore activity || 1 -0.34 -0.39 -0.78 -0.97 -0.02 -0.33 -0.48 -0.54 -1.02 -0.97 -0.56 -0.80 -0.30 -0.51 -0.50 -0.78
8518 || orf19.3944 || GRR1 || || F-box protein component of the SCF ubiquitin-ligase complex required for cell cycle progression; involved in negative control of pseudohyphal growth; Spider biofilm induced || 1 -0.36 -0.32 -1.05 -0.96 -0.26 -0.47 -0.25 -0.67 -0.72 -0.74 -0.34 -0.71 -0.29 -0.33 -0.19 -0.20
8519 || orf19.3216 || || || Similar to Rab GTPase activators; Hap43p-induced gene || 1 -0.47 -0.56 -1.05 -0.92 -0.98 -1.12 -0.75 -1.04 -1.39 -1.10 -1.00 -1.01 -0.22 -1.08 -0.89 -1.14
8520 || orf19.3429 || FGR47 || || Protein lacking an ortholog in S. cerevisiae; transposon mutation affects filamentous growth || 1 -0.64 -0.45 -1.33 -1.17 -0.92 -1.14 -0.98 -1.41 -1.48 -1.29 -1.09 -1.58 -0.01 -0.99 -0.90 -0.96
8521 || orf19.4647 || HAP3 || || Predicted CCAAT-binding transcription factor that regulates respiration; Cap2-dependent induction in low iron; opaque specific, alkaline, ciclopirox olamine induced; regulated by Sef1, Sfu1, Hap43; Bcr1-regulated in RPMI a/a biofilms || 1 -0.35 -0.77 -1.94 -1.12 -0.88 -0.89 -1.20 -1.22 -1.50 -1.27 -1.18 -1.95 -0.15 -1.06 -1.77 -1.08
8522 || orf19.3801 || FAV1 || || Protein with weak similarity to S. cerevisiae Fus2p; induced by alpha pheromone mating factor in MTLa/MTLa opaque cells || 1 -0.69 -0.37 -1.25 -0.99 -0.26 -0.61 -0.51 -0.95 -1.11 -0.53 -0.78 -1.11 0.37 -0.54 -0.60 -0.57
8523 || orf19.5579 || || || Protein with a predicted double-strand break repair domain; Hap43-repressed gene || 1 -0.61 -0.55 -1.57 -1.49 -0.61 -0.64 -0.52 -1.26 -1.35 -1.03 -0.66 -1.02 0.45 -0.56 -0.44 -0.34
8524 || orf19.1302 || || || Ortholog of C. dubliniensis CD36 : Cd36_43500, Spathaspora passalidarum NRRL Y-27907 : SPAPADRAFT_64619, Candida tropicalis MYA-3404 : CTRG_00335 and Candida albicans WO-1 : CAWG_03437 || 1 -0.68 -0.55 -1.57 -1.37 -0.69 -0.57 -0.90 -1.65 -1.77 -1.44 -0.73 -1.08 0.34 -0.68 -0.36 -0.58
8525 || orf19.1302 || || || Ortholog of C. dubliniensis CD36 : Cd36_43500, Spathaspora passalidarum NRRL Y-27907 : SPAPADRAFT_64619, Candida tropicalis MYA-3404 : CTRG_00335 and Candida albicans WO-1 : CAWG_03437 || 1 -0.65 -0.59 -1.55 -1.39 -0.65 -0.61 -0.80 -1.62 -1.68 -1.37 -0.89 -1.11 0.26 -0.63 -0.33 -0.71
8526 || orf19.1302 || || || Ortholog of C. dubliniensis CD36 : Cd36_43500, Spathaspora passalidarum NRRL Y-27907 : SPAPADRAFT_64619, Candida tropicalis MYA-3404 : CTRG_00335 and Candida albicans WO-1 : CAWG_03437 || 1 -0.62 -0.59 -1.61 -1.38 -0.63 -0.62 -0.86 -1.56 -1.62 -1.42 -0.89 -1.33 0.28 -1.01 -0.44 -0.77
8527 || orf19.1302 || || || Ortholog of C. dubliniensis CD36 : Cd36_43500, Spathaspora passalidarum NRRL Y-27907 : SPAPADRAFT_64619, Candida tropicalis MYA-3404 : CTRG_00335 and Candida albicans WO-1 : CAWG_03437 || 1 -0.64 -0.68 -1.55 -1.27 -0.81 -0.67 -0.77 -1.49 -1.86 -1.34 -0.92 -1.35 0.08 -1.07 -0.46 -0.62
8528 || orf19.1302 || || || Ortholog of C. dubliniensis CD36 : Cd36_43500, Spathaspora passalidarum NRRL Y-27907 : SPAPADRAFT_64619, Candida tropicalis MYA-3404 : CTRG_00335 and Candida albicans WO-1 : CAWG_03437 || 1 -0.81 -0.77 -1.51 -1.38 -0.89 -0.71 -0.89 -1.54 -1.76 -1.46 -0.93 -1.32 0.06 -1.17 -0.44 -0.48
8529 || orf19.2222 || || || Putative casein kinase; plasma membrane-localized || 1 -0.52 -0.39 -0.74 -0.65 -0.55 -0.67 -0.70 -1.18 -1.05 -0.80 -0.79 -0.66 0.28 -0.67 -0.36 -0.23
8530 || orf19.233.1 || HRT1 || || Ortholog of S. cerevisiae Hrt1; component of a nuclear ubiquitin-protein ligase complex involved in cell cycle control; induced by hydroxyurea; Spider biofilm induced || 1 -0.88 -1.19 -0.85 -0.76 -1.38 -1.30 -1.14 -1.06 -1.37 -0.58 -1.16 -0.82 0.31 -0.60 -0.63 -0.83
8531 || orf19.262 || SMC3 || || Protein similar to S. cerevisiae Smc3p, which is an ATPase involved in sister chromatid cohesion; likely to be essential for growth, based on an insertional mutagenesis strategy || 1 -1.16 -1.01 -1.45 -0.95 -1.19 -1.50 -0.80 -1.38 -1.63 -0.63 -0.58 -0.95 0.00 -0.94 -0.94 -0.66
8532 || orf19.4866 || CPP1 || || VH1 family MAPK phosphatase; regulates Cst20-Hst7-Cek1-Cph1 filamentation pathway; represses yeast-hyphal switch; required for virulence in mice; yeast-enriched; induced by alpha pheromone in SpiderM medium; Spider biofilm induced || 1 -0.69 -0.52 -0.90 -0.82 -0.75 -1.28 -0.30 -0.54 -0.87 -0.67 -0.74 -0.88 0.15 -0.43 -0.60 -0.58
8533 || orf19.6984 || || || Ortholog of C. dubliniensis CD36 : Cd36_85460, C. parapsilosis CDC317 : CPAR2_405760, Candida tenuis NRRL Y-1498 : CANTEDRAFT_116052 and Debaryomyces hansenii CBS767 : DEHA2D16940g || 1 -1.06 -0.93 -1.58 -1.04 -0.85 -1.21 -0.40 -0.61 -0.77 0.00 -0.86 -0.84 -0.12 -0.62 -0.64 -0.58
8534 || orf19.6970 || || || Ortholog of C. dubliniensis CD36 : Cd36_85310, C. parapsilosis CDC317 : CPAR2_807370, Candida tenuis NRRL Y-1498 : CANTEDRAFT_115544 and Debaryomyces hansenii CBS767 : DEHA2D11770g || 1 -0.56 -0.59 -0.68 -0.34 -0.65 -0.36 -0.24 -0.81 -0.94 -0.73 -0.28 -0.63 0.42 -0.25 -0.34 -0.05
8535 || orf19.6970 || || || Ortholog of C. dubliniensis CD36 : Cd36_85310, C. parapsilosis CDC317 : CPAR2_807370, Candida tenuis NRRL Y-1498 : CANTEDRAFT_115544 and Debaryomyces hansenii CBS767 : DEHA2D11770g || 1 -0.74 -0.59 -0.44 -0.48 -0.53 -0.59 -0.30 -1.02 -1.03 -0.72 -0.28 -0.23 0.35 -0.19 -0.34 -0.10
8536 || orf19.6970 || || || Ortholog of C. dubliniensis CD36 : Cd36_85310, C. parapsilosis CDC317 : CPAR2_807370, Candida tenuis NRRL Y-1498 : CANTEDRAFT_115544 and Debaryomyces hansenii CBS767 : DEHA2D11770g || 1 -0.46 -0.54 -0.42 -0.36 -0.51 -0.44 -0.51 -1.15 -0.77 -0.71 -0.39 -0.35 0.38 -0.12 -0.57 -0.14
8537 || orf19.6970 || || || Ortholog of C. dubliniensis CD36 : Cd36_85310, C. parapsilosis CDC317 : CPAR2_807370, Candida tenuis NRRL Y-1498 : CANTEDRAFT_115544 and Debaryomyces hansenii CBS767 : DEHA2D11770g || 1 -0.63 -0.47 -0.54 -0.30 -0.47 -0.26 -0.58 -1.13 -0.94 -0.71 -0.23 -0.15 0.51 -0.19 -0.64 -0.15
8538 || orf19.6970 || || || Ortholog of C. dubliniensis CD36 : Cd36_85310, C. parapsilosis CDC317 : CPAR2_807370, Candida tenuis NRRL Y-1498 : CANTEDRAFT_115544 and Debaryomyces hansenii CBS767 : DEHA2D11770g || 1 -0.75 -0.43 -0.82 -0.47 -0.34 -0.41 -0.65 -1.12 -1.26 -0.74 -0.45 -0.51 0.51 -0.29 -0.68 -0.08
8539 || orf19.3563 || || || Ortholog of C. dubliniensis CD36 : Cd36_19810, C. parapsilosis CDC317 : CPAR2_206450, Candida tenuis NRRL Y-1498 : CANTEDRAFT_113905 and Debaryomyces hansenii CBS767 : DEHA2C05566g || 1 -0.41 -0.39 -0.94 -0.52 -0.41 -0.50 0.08 -0.55 -0.56 -0.70 -0.20 -0.50 0.32 -0.04 -0.32 -0.29
8540 || orf19.5404 || || || Putative cell wall mannoprotein; repressed during the mating process; merged with orf19.5401 into orf19.5404.1; Spider biofilm induced || 1 -0.98 -0.77 -1.36 -0.83 -0.39 -0.49 -0.10 -0.40 -0.54 -0.80 -0.44 -0.86 0.18 -0.29 -0.70 -0.15
8541 || orf19.5274 || || || Ortholog(s) have cellular bud neck, cellular bud tip, cytoplasm localization || 1 -0.48 -0.37 -0.74 -0.50 -0.27 0.08 -0.34 -0.87 -0.59 -0.43 -0.39 -0.37 0.47 -0.05 -0.04 0.03
8542 || orf19.4184 || || || Protein with a predicted role in clathrin cage assembly; Hap43-repressed; Spider biofilm repressed || 1 -0.35 -0.33 -0.64 -0.38 -0.23 -0.12 -0.36 -0.87 -0.43 -0.48 -0.57 -0.85 0.42 -0.17 -0.09 -0.06
8543 || orf19.4961 || STP2 || || Amino-acid-regulated transcription factor; activates transcription of amino acid permease genes; activated by amino-acid-induced proteolytic processing (Ssy1, Csh3 dependent); required for alkalinization of medium; Spider biofilm induced || 1 -0.44 -0.33 -0.77 -0.70 -0.46 -0.40 -0.25 -0.88 -0.93 -0.66 -0.28 -0.76 0.32 -0.67 0.35 0.16
8544 || orf19.5223 || || || Ortholog of Candida albicans WO-1 : CAWG_00199 || 1 -0.19 -0.08 -0.47 -0.14 -0.35 -0.60 -0.34 -0.70 -0.58 -0.53 -0.19 -0.56 0.40 -0.32 0.29 -0.13
8545 || orf19.5223 || || || Ortholog of Candida albicans WO-1 : CAWG_00199 || 1 -0.14 -0.23 -0.42 -0.14 -0.36 -0.60 -0.35 -0.79 -0.59 -0.51 -0.42 -0.47 0.49 -0.30 0.28 -0.06
8546 || orf19.5223 || || || Ortholog of Candida albicans WO-1 : CAWG_00199 || 1 -0.17 -0.10 -0.52 -0.15 -0.35 -0.51 -0.44 -0.74 -0.52 -0.52 -0.46 -0.62 0.41 -0.15 0.31 -0.14
8547 || orf19.5223 || || || Ortholog of Candida albicans WO-1 : CAWG_00199 || 1 -0.08 0.09 -0.31 -0.05 -0.16 -0.42 -0.40 -0.69 -0.41 -0.39 -0.33 -0.44 0.68 -0.21 0.25 0.08
8548 || orf19.2534 || PIN4 || || Protein with similarity to S. cerevisiae Pin4p; transposon mutation affects filamentous growth || 1 -0.45 -0.36 -1.02 -0.42 0.09 -0.52 -0.45 -0.60 -0.63 -0.30 -0.48 -0.32 0.38 -0.06 -0.23 0.08
8549 || orf19.5558 || RBF1 || || Transcription factor; glutamine-rich activation domain; binds RPG-box DNA sequences; predominantly nuclear; mutation causes accelerated induction of filamentous growth; antigenic during human oral infection; Sko1p-repressed || 1 -0.30 -0.33 -0.52 -0.74 -0.64 -0.45 -0.68 -0.42 -0.65 -0.46 -0.21 -0.44 0.10 -0.37 -1.04 0.35
8550 || orf19.1729 || || || Putative transcription factor with zinc finger DNA-binding motif || 1 -0.31 -0.14 -0.26 -0.30 -0.98 -0.60 -0.45 -0.47 -0.65 -1.07 -0.40 -0.35 -0.19 -0.43 -0.70 0.12
8551 || orf19.5526 || SEC20 || || Essential protein; similar to S. cerevisiae Sec20p; depletion causes membrane accumulation and drug sensitivity; expression regulated by growth phase; O-mannosylation regulates proteolysis; does not complement S. cerevisiae sec20-1 mutant || 1 -0.27 -0.39 -0.36 -0.41 -0.17 -0.62 -0.46 -0.39 -0.73 -1.09 -0.05 -0.22 -0.26 -0.70 -0.57 -0.13
8552 || orf19.1348 || || || Ortholog of C. dubliniensis CD36 : Cd36_22500, Candida tropicalis MYA-3404 : CTRG_01825 and Candida albicans WO-1 : CAWG_05921 || 1 -0.62 -0.39 -0.53 -0.29 -0.23 -0.27 -0.75 -0.99 -0.72 -0.46 -0.59 -0.59 -0.22 -1.20 -0.52 0.12
8553 || orf19.6917 || || || Putative heat shock protein with a zinc finger motif; required for protein import into mitochondria in S. cerevisiae; Spider biofilm induced || 1 -0.29 -0.21 -0.52 -0.54 -0.09 0.42 -0.55 -0.80 -1.32 -0.05 -0.28 -0.36 -0.54 -0.53 -0.22 -0.78
8554 || orf19.1886 || RCL1 || || Putative U3-containing 90S preribosome processome complex subunit; Hap43-induced; essential; S. cerevisiae ortholog is essential; represses in core stress response; || 1 -1.03 -1.03 -0.83 -1.13 -0.36 0.67 -0.48 -0.88 -1.49 0.49 -0.56 -1.01 -0.78 -0.61 -1.14 -0.69
8555 || orf19.7546 || || || Protein involved in rRNA processing; required for maturation of the 35S primary transcript of pre-rRNA and for cleavage leading to mature 18S rRNA; Spider biofilm induced || 1 -0.51 -0.60 -1.12 -1.11 -0.13 0.62 -0.51 -1.22 -1.06 0.64 -0.83 -0.93 -0.08 -0.31 -0.29 -0.65
8556 || orf19.2384 || MTG1 || || Putative mitochondrial GTPase; likely essential for respiratory competence and in large ribosomal subunit assembly; mitochondrial translation; Spider biofilm induced || 1 -1.25 -1.21 -1.25 -1.13 0.19 0.68 -0.88 -1.23 -1.11 0.25 -1.23 -0.59 -0.13 -0.56 -0.36 -1.33
8557 || orf19.6577 || FLU1 || || Multidrug efflux pump of the plasma membrane; MDR family member of the MFS (major facilitator superfamily) of transporters; involved in histatin 5 efflux; fungal-specific (no human/murine homolog) || 1 -1.28 -1.14 -1.57 -0.52 -0.37 0.63 -0.87 -1.38 -1.80 -0.35 -0.97 -1.01 -0.82 -0.74 -0.26 -1.00
8558 || orf19.5391 || || || Predicted RNA splicing and ER to Golgi transport protein; Hap43-induced gene || 1 -0.63 -0.65 -0.84 -0.88 -0.53 0.00 -0.97 -0.85 -0.97 -0.23 -0.48 -0.44 -0.21 -0.42 -0.63 -0.44
8559 || orf19.4499 || RIM2 || || Putative mitochondrial carrier protein; induced by alpha pheromone in SpiderM medium; Spider biofilm induced || 1 -1.06 -1.22 -1.29 -1.75 -0.53 -0.22 -0.37 -0.59 -0.74 0.01 -0.70 -0.57 -0.03 0.01 -0.31 -1.41
8560 || orf19.5039 || RRP42 || || Putative exosome non-catalytic core component; involved in 3'-5' RNA processing; rat catheter biofilm induced || 1 -0.23 -0.53 -1.18 -1.42 -0.18 0.07 0.10 -0.83 -1.15 -0.11 -0.36 -0.67 -0.20 -0.28 -0.21 -1.30
8561 || orf19.3671 || || || Dubious open reading frame || 1 -0.92 -0.72 -1.61 -1.12 -0.13 0.30 -0.46 -0.83 -0.35 0.10 -1.39 0.28 -0.19 0.48 -0.11 -0.70
8562 || orf19.6845 || || || Putative transcription factor with bZIP DNA-binding motif; rat catheter biofilm induced || 1 -0.62 -0.56 -0.84 -0.73 -0.41 0.45 -0.05 -0.96 -0.40 0.22 -0.64 -0.12 -0.13 0.01 -0.25 -0.24
8563 || orf19.2942 || DIP5 || || Dicarboxylic amino acid permease; mutation confers hypersensitivity to toxic ergosterol analog; induced upon phagocytosis by macrophage; Gcn4-regulated; upregulated by Rim101 at pH 8; rat catheter and Spider biofilm induced || 1 -0.81 -0.91 -0.84 -0.99 -0.43 0.20 -0.47 -1.44 -0.70 0.00 -1.28 -1.06 -0.33 0.41 0.29 -0.31
8564 || orf19.2514 || || || Predicted methyltransferase; rat catheter biofilm induced || 1 -0.37 -0.62 -0.88 -0.26 -0.47 -0.00 -0.25 -0.64 -0.46 -0.14 -0.66 -0.35 -0.66 -0.11 0.30 -0.00
8565 || orf19.4475 || KTR4 || || Mannosyltransferase; induced during cell wall regeneration; fungal-specific (no human or murine homolog); Bcr1-repressed in RPMI a/a biofilms || 1 -0.41 -0.71 -0.33 -0.69 -0.08 -0.42 -0.62 -0.57 -0.65 -0.40 -0.47 -0.14 -0.40 -0.28 0.50 -0.03
8566 || orf19.7672 || || || Ortholog(s) have role in ER-associated ubiquitin-dependent protein catabolic process, endoplasmic reticulum unfolded protein response || 1 -0.84 -0.76 -0.62 -0.37 -0.22 -0.32 -0.82 -0.63 -0.99 0.04 -0.31 -0.25 -0.54 -0.77 0.72 -0.55
8567 || orf19.7670 || || || Putative Ca2+/H+ antiporter; oral infection upregulated gene; mutants have reduced capacity to damage oral epithelial cells || 1 -1.07 -1.27 -0.85 -0.90 0.03 -0.07 -0.76 -0.46 -0.72 -0.68 -0.44 -0.41 -0.28 -0.66 0.38 -0.67
8568 || orf19.7460 || || || Putative 2'-O-methyltransferase with a predicted role in tRNA modification; transcription is activated in the presence of elevated CO2 || 1 -0.36 -0.24 -0.27 -0.20 -0.11 0.25 -0.20 -0.39 -0.27 -0.12 -0.62 -0.04 -0.18 -0.39 0.01 -0.31
8569 || orf19.3507 || MCR1 || || NADH-cytochrome-b5 reductase; soluble in hyphae; alkaline downregulated; farnesol, ketoconazole or flucytosine induced; protein present in exponential and stationary growth phase yeast; YNB biofilm induced; rat catheter biofilm repressed || 1 -0.43 -0.42 -0.44 -0.11 -0.35 0.10 -0.37 -0.31 -0.33 -0.48 -0.54 -0.49 -0.19 -0.48 0.31 -0.57
8570 || orf19.6578 || || || Predicted membrane transporter; vesicular neurotransmitter (VNT) family, major facilitator superfamily (MFS); repressed in core caspofungin response; induced in oralpharyngeal candidasis; Spider biofilm induced || 1 -1.26 -1.35 -0.12 -0.34 -0.82 -0.26 -0.93 -1.21 -0.75 0.04 -1.48 -0.95 -0.61 -0.61 0.46 -1.64
8571 || orf19.2942 || DIP5 || || Dicarboxylic amino acid permease; mutation confers hypersensitivity to toxic ergosterol analog; induced upon phagocytosis by macrophage; Gcn4-regulated; upregulated by Rim101 at pH 8; rat catheter and Spider biofilm induced || 1 -0.57 -0.78 -0.10 -0.41 -0.19 0.03 -0.28 -1.26 -0.82 -0.28 -0.75 -1.64 -0.00 -0.13 0.06 -0.77
8572 || orf19.2229 || || || Ortholog(s) have ubiquitin-protein ligase activity, role in protein ubiquitination, response to ethanol and cytoplasm, nucleus localization || 1 -0.18 -0.27 -0.53 -0.11 -0.22 -0.31 -0.33 -0.70 -0.58 -0.27 -0.70 -1.07 0.23 -0.14 0.69 -0.58
8573 || orf19.1534 || || || Ortholog of S. cerevisiae Zrt3, vacuolar membrane zinc transporter; predicted Kex2 substrate; induced in oralpharyngeal candidasis; flow model biofilm induced; Spider biofilm induced || 1 -1.55 -1.47 -0.23 -1.01 -0.29 0.05 -0.71 -0.85 -0.47 -1.06 -0.99 -0.76 2.05 0.85 -0.02 0.29
8574 || orf19.101 || RIM9 || || Protein required for alkaline pH response via the Rim101 signaling pathway; ortholog of S. cerevisiae Rim9 and A. nidulans palI; Spider biofilm induced || 1 -1.80 -1.68 -1.13 -1.32 -0.36 -0.21 -1.15 -1.34 -0.78 -1.01 -0.68 -0.28 1.32 0.84 -0.15 0.37
8575 || orf19.1616 || FGR23 || || Protein of unknown function; repressed by a1/alpha2 in white-phase cells, a-specific, alpha factor-induced; Hap43-repressed; flow model biofilm induced; Tn mutation affects filamentous growth; || 1 -0.53 -0.51 -0.94 -1.47 -0.06 -0.19 -0.19 -1.19 -1.08 -2.09 -0.86 -1.03 0.81 -0.42 -1.04 0.50
8576 || orf19.4802 || FTH1 || || Protein similar to S. cerevisiae Fth1p, a high affinity iron transporter for intravacuolar stores of iron; repressed by Sfu1p, amphotericin B, caspofungin; induced by alkaline pH, ciclopirox olamine; regulated by Sef1p, Sfu1p, and Hap43p || 1 -0.69 -0.27 -1.30 -1.45 0.30 -1.21 -0.69 -0.01 -2.59 -2.44 0.02 -1.97 1.04 1.21 0.42 0.93
8577 || orf19.4802 || FTH1 || || Protein similar to S. cerevisiae Fth1p, a high affinity iron transporter for intravacuolar stores of iron; repressed by Sfu1p, amphotericin B, caspofungin; induced by alkaline pH, ciclopirox olamine; regulated by Sef1p, Sfu1p, and Hap43p || 1 -1.72 -1.56 -2.91 -2.55 -0.91 -1.61 -1.26 -1.34 -3.32 -4.18 -1.36 -2.23 1.49 1.81 0.13 0.85
8578 || orf19.5063 || COI1 || || Secreted protein; ciclopirox olamine induced; regulated by Ssn6; induced by nitric oxide independent of Yhb1; Hap43-induced; Spider biofilm repressed || 1 -0.81 -0.80 -1.93 -2.28 -0.95 -1.16 -0.56 -0.80 -1.98 -3.47 0.04 -0.38 1.75 1.02 -0.88 0.78
8579 || orf19.5063 || COI1 || || Secreted protein; ciclopirox olamine induced; regulated by Ssn6; induced by nitric oxide independent of Yhb1; Hap43-induced; Spider biofilm repressed || 1 -0.87 -0.88 -1.70 -1.88 -0.97 -1.06 -0.61 -0.80 -2.06 -3.78 0.08 -0.20 1.73 1.20 -0.99 0.95
8580 || orf19.5063 || COI1 || || Secreted protein; ciclopirox olamine induced; regulated by Ssn6; induced by nitric oxide independent of Yhb1; Hap43-induced; Spider biofilm repressed || 1 -0.84 -0.85 -1.84 -2.21 -1.00 -0.97 -0.57 -0.71 -2.38 -3.93 0.20 -0.11 1.77 1.20 -0.90 1.32
8581 || orf19.5063 || COI1 || || Secreted protein; ciclopirox olamine induced; regulated by Ssn6; induced by nitric oxide independent of Yhb1; Hap43-induced; Spider biofilm repressed || 1 -0.82 -0.86 -1.66 -2.02 -0.88 -1.11 -0.45 -0.76 -1.88 -3.63 0.20 -0.09 1.61 1.25 -1.01 1.30
8582 || orf19.5063 || COI1 || || Secreted protein; ciclopirox olamine induced; regulated by Ssn6; induced by nitric oxide independent of Yhb1; Hap43-induced; Spider biofilm repressed || 1 -0.86 -0.97 -1.28 -1.75 -1.09 -1.05 -0.41 -0.55 -2.29 -3.50 0.14 -0.38 1.72 1.06 -0.87 0.95
8583 || orf19.4905 || || || Putative MFS transporter; Hap43p-induced gene; also regulated by regulated by Sef1p and Sfu1p; repressed in a ssr1 null mutant || 1 -0.57 -0.62 -0.64 -0.84 -0.67 -0.64 -0.33 -0.38 -0.60 -1.13 -0.46 -0.25 -0.20 0.93 -0.37 0.57
8584 || orf19.4905 || || || Putative MFS transporter; Hap43p-induced gene; also regulated by regulated by Sef1p and Sfu1p; repressed in a ssr1 null mutant || 1 -0.97 -1.29 -1.59 -1.26 -0.88 -1.00 -0.73 -0.69 -0.79 -1.54 -0.32 -0.45 -0.00 0.73 -0.75 0.28
8585 || orf19.1932 || CFL4 || || C-terminus similar to ferric reductases; induced in low iron; Sfu1-repressed; ciclopirox olamine induced; colony morphology-related gene regulation by Ssn6; Hap43-repressed; Sef1-regulated || 1 -1.56 -1.70 -3.38 -2.83 -2.18 -1.99 -1.45 -1.31 -2.04 -3.03 -2.96 1.84 1.70 -2.58 0.52
8586 || orf19.1415 || FRE10 || || Major cell-surface ferric reductase under low-iron conditions; 7 transmembrane regions and a secretion signal predicted; Tup1, Rim101, Ssn6, Hog1, caspofungin repressed; ciclopirox olamine induced; rat catheter biofilm induced || 1 -0.85 -0.93 -2.13 -2.00 -1.54 -0.58 -0.28 -0.51 -1.35 -1.91 -1.64 -1.50 0.74 1.00 -0.68 -0.02
8587 || orf19.1415 || FRE10 || || Major cell-surface ferric reductase under low-iron conditions; 7 transmembrane regions and a secretion signal predicted; Tup1, Rim101, Ssn6, Hog1, caspofungin repressed; ciclopirox olamine induced; rat catheter biofilm induced || 1 -0.59 -0.62 -1.94 -1.93 -1.30 -0.47 -0.13 -0.36 -1.08 -1.65 -1.33 -1.32 0.91 1.33 -0.30 0.22
8588 || orf19.681 || HAP43 || || CCAAT-binding factor-dependent transcription factor; repressor; also called CAP2; required for low iron response; similar to bZIP transcription factor AP-1; repressed by Sfu1; ciclopirox olamine induced; rat catheter, Spider biofilm induced || 1 -0.75 -0.90 -1.49 -1.71 -1.23 -1.27 -0.40 -1.00 -1.20 -1.58 -1.16 -1.06 1.48 0.92 -0.28 0.06
8589 || orf19.681 || HAP43 || || CCAAT-binding factor-dependent transcription factor; repressor; also called CAP2; required for low iron response; similar to bZIP transcription factor AP-1; repressed by Sfu1; ciclopirox olamine induced; rat catheter, Spider biofilm induced || 1 -0.65 -0.88 -0.88 -1.25 -1.28 -0.92 -0.58 -1.30 -0.93 -1.36 -1.20 -0.79 1.38 0.69 -0.43 0.35
8590 || orf19.4211 || FET3 || || Multicopper oxidase; for growth in low iron, prostaglandin E2 synthesis; ketoconazole/caspofungin/amphotericin B repressed; Sef1/Sfu1/Hap43 regulated; reports differ if functional homolog of ScFet3; rat catheter and Spider biofilm induced || 1 -0.63 -0.68 -1.03 -0.75 -1.08 -0.97 -0.60 -0.60 -0.30 -1.15 -0.78 -0.58 1.42 1.33 -0.58 0.25
8591 || orf19.7219 || FTR1 || || High-affinity iron permease; required for mouse virulence, low-iron growth; iron, amphotericin B, caspofungin, ciclopirox, Hog1p, Sef1p, Sfu1p, and Hap43p regulated; complements S. cerevisiae ftr1 iron transport; Hap43p-repressed || 1 -0.64 -0.75 -1.12 -0.92 -1.36 -1.06 -0.40 -0.91 -1.08 -2.66 -1.30 -0.72 1.29 1.23 -1.52 0.50
8592 || orf19.7219 || FTR1 || || High-affinity iron permease; required for mouse virulence, low-iron growth; iron, amphotericin B, caspofungin, ciclopirox, Hog1p, Sef1p, Sfu1p, and Hap43p regulated; complements S. cerevisiae ftr1 iron transport; Hap43p-repressed || 1 -0.75 -0.80 -1.05 -0.94 -1.42 -1.04 -0.59 -1.07 -1.26 -2.50 -1.27 -1.07 1.20 0.54 -1.65 0.59
8593 || orf19.7231 || FTR2 || || High-affinity iron permease; probably interacts with ferrous oxidase; regulated by iron level, ciclopirox olamine, amphotericin B, caspofungin; complements S. cerevisiae ftr1 iron transport defect; Hap43-repressed; Spider biofilm induced || 1 -0.66 -0.83 -1.06 -0.86 -1.24 -1.06 -0.72 -1.14 -1.20 -1.98 -1.18 -0.93 0.80 0.50 -1.49 0.26
8594 || orf19.7231 || FTR2 || || High-affinity iron permease; probably interacts with ferrous oxidase; regulated by iron level, ciclopirox olamine, amphotericin B, caspofungin; complements S. cerevisiae ftr1 iron transport defect; Hap43-repressed; Spider biofilm induced || 1 -0.67 -0.89 -0.85 -0.71 -1.27 -0.82 -0.48 -0.83 -1.21 -1.59 -1.15 -0.66 0.75 0.16 -1.67 0.13
8595 || orf19.5952 || || || Protein of unknown function; induced by nitric oxide independent of Yhb1; Sef1, Sfu1, and Hap43-induced; rat catheter and Spider biofilm induced || 1 -0.61 -0.37 -0.97 -1.08 -0.69 -0.83 -1.56 -1.63 -1.33 -2.18 -1.04 -1.00 0.63 0.81 -0.38 0.01
8596 || orf19.5952 || || || Protein of unknown function; induced by nitric oxide independent of Yhb1; Sef1, Sfu1, and Hap43-induced; rat catheter and Spider biofilm induced || 1 -0.60 -0.68 -1.54 -1.52 -0.83 -1.38 -2.31 -2.66 -1.91 -3.20 -1.44 -1.46 1.01 1.38 -0.43 -0.28
8597 || orf19.5952 || || || Protein of unknown function; induced by nitric oxide independent of Yhb1; Sef1, Sfu1, and Hap43-induced; rat catheter and Spider biofilm induced || 1 -0.27 -0.20 -0.43 -1.06 -0.17 -1.21 -1.22 -0.95 -1.86 -1.87 -0.82 -0.88 0.90 1.94 -0.60 0.33
8598 || orf19.5952 || || || Protein of unknown function; induced by nitric oxide independent of Yhb1; Sef1, Sfu1, and Hap43-induced; rat catheter and Spider biofilm induced || 1 0.05 -0.02 -0.89 -0.81 -0.17 -0.97 -1.20 -0.77 -0.93 -1.82 -0.94 -0.60 1.35 1.81 -0.13 0.30
8599 || orf19.3538 || FRE9 || || Ferric reductase; alkaline induced; ciclopirox olamine; Hap43-induced || 1 -0.88 -0.87 -1.55 -0.81 -0.01 -0.50 -0.31 -1.02 -0.47 -1.24 -1.47 -0.83 1.56 2.03 0.83 0.84
8600 || orf19.3538 || FRE9 || || Ferric reductase; alkaline induced; ciclopirox olamine; Hap43-induced || 1 -0.25 -0.21 -1.52 -0.92 -0.34 -0.68 -0.43 -1.01 -1.01 -1.36 -1.51 -1.36 1.22 1.00 0.66 0.99
8601 || orf19.3538 || FRE9 || || Ferric reductase; alkaline induced; ciclopirox olamine; Hap43-induced || 1 -0.50 -0.40 -0.83 -0.89 -0.29 -0.10 -0.01 -0.63 -0.58 -0.94 -1.12 -0.79 0.84 0.85 0.23 0.92
8602 || orf19.3538 || FRE9 || || Ferric reductase; alkaline induced; ciclopirox olamine; Hap43-induced || 1 -0.61 -0.66 -0.81 -1.12 0.00 -0.70 -0.38 -0.89 -0.78 -1.19 -0.95 -1.09 0.80 0.92 0.37 0.82
8603 || orf19.3538 || FRE9 || || Ferric reductase; alkaline induced; ciclopirox olamine; Hap43-induced || 1 -1.06 -1.39 -0.92 -1.10 0.00 -0.56 -0.62 -1.28 -1.16 -1.67 -0.98 -1.32 1.13 0.97 0.54 1.18
8604 || orf19.5773 || || || Putative dipeptidyl-peptidase III; protein detected by mass spec in exponential and stationary phase cultures; Hog1p-induced; clade-associated gene expression || 1 -0.17 -0.13 -0.19 -0.56 -0.19 -0.56 -0.15 -0.08 -0.13 -0.70 -0.09 -0.12 0.02 0.46 -0.02 0.12
8605 || orf19.4677 || || || Putative protein of unknown function, transcript is upregulated in clinical isolates from HIV+ patients with oral candidiasis; Spider biofilm induced || 1 -0.61 -0.57 0.15 -0.27 -0.45 -0.26 -0.50 -0.79 -0.54 -0.29 -0.43 0.10 -0.68 0.16 -0.43 -0.23
8606 || orf19.7001 || YCK2 || || Plasma membrane protein similar to S. cerevisiae casein kinase I, Yck2p; null mutant has defect in damaging oral epithelial cells and in hyphal branching; transcription is activated in weak acid stress or on contact with host cells || 1 -0.64 -0.61 -0.00 -0.34 -0.47 -0.42 -0.33 -0.60 -0.39 -0.15 -0.41 0.05 -0.53 0.28 -0.06 0.26
8607 || orf19.4706 || || || Protein of unknown function; induced in cyr1 or ras1 mutant; induced by fluconazole, by alpha pheromone in SpiderM medium and during oralpharyngeal candidasis; Spider biofilm induced || 1 -1.55 -1.50 0.12 -0.64 -0.15 -0.46 -0.47 -1.78 -1.15 -0.90 -1.35 -1.03 -0.85 0.08 0.63 -0.23
8608 || orf19.4174 || || || Ortholog(s) have nicotinamide riboside transmembrane transporter activity, role in nicotinamide riboside transport, transmembrane transport and fungal-type vacuole membrane localization || 1 -0.39 -0.51 -0.11 -0.30 -0.42 -0.48 -0.53 -0.72 -0.37 -0.80 -0.58 -0.37 -0.12 0.25 -0.12 0.11
8609 || orf19.2887 || || || Ortholog in S. cerevisiae is localizedto the bud, mating projection tip, and associates with ribosomes; Spider biofilm induced || 1 -0.51 -0.52 -0.49 -0.41 -0.44 -0.63 -0.42 -0.73 -0.66 -0.85 -1.17 -0.42 -0.42 0.13 0.09 -0.43
8610 || orf19.2887 || || || Ortholog in S. cerevisiae is localizedto the bud, mating projection tip, and associates with ribosomes; Spider biofilm induced || 1 -0.47 -0.65 -0.16 0.11 -0.39 -0.11 -0.62 -0.71 -0.38 -0.75 -0.96 0.02 -0.55 0.21 0.24 -0.27
8611 || orf19.3610 || || || Protein of unknown function; upregulation correlates with clinical development of fluconazole resistance; regulated by Sef1, Sfu1, and Hap43 || 1 -0.76 -0.87 -0.40 -0.36 -0.66 -0.19 -0.47 -1.09 -0.30 -0.92 -1.08 0.01 -0.17 0.52 0.18 0.40
8612 || orf19.7359 || CRZ1 || || Calcineurin-regulated C2H2 transcription factor; role in maintenance of membrane integrity, azole tolerance; not required for mouse virulence; repressed by low iron; regulates Ca++ influx during alkaline pH response; Spider biofilm induced || 1 -1.26 -1.33 0.02 -0.12 -0.48 0.19 -0.58 -1.40 -0.35 -0.70 -1.06 0.11 -0.45 0.34 -0.38 0.01
8613 || orf19.589 || VPS21 || || Late endosomal Rab small monomeric GTPase involved in transport of endocytosed proteins to the vacuole; involved in filamentous growth and virulence; Spider biofilm induced || 1 -0.43 -0.69 -0.11 -0.05 -0.34 0.31 -0.33 -0.71 -0.30 -0.51 -0.64 -0.13 -0.31 -0.09 -0.06 0.38
8614 || orf19.5813 || || || Putative adhesin-like protein; upregulated during growth in the mouse cecum; flow model, rat catheter and Spider biofilm induced || 1 -1.29 -1.39 -0.81 -0.75 -0.71 0.20 -0.02 -1.09 -0.75 -1.39 -0.81 -1.10 -0.54 0.08 0.29 0.03
8615 || orf19.5813 || || || Putative adhesin-like protein; upregulated during growth in the mouse cecum; flow model, rat catheter and Spider biofilm induced || 1 -1.14 -1.26 -0.95 -0.96 -0.50 0.28 0.09 -1.17 -0.62 -1.48 -0.54 -0.94 -0.64 0.41 0.47 0.13
8616 || orf19.2204 || || || Predicted membrane protein of unknown function; Spider biofilm induced || 1 -0.76 -0.97 -0.25 -0.31 -0.27 0.41 -0.30 -0.79 0.26 -1.26 -0.78 -0.12 -0.28 0.17 0.15 -0.27
8617 || orf19.2204 || || || Predicted membrane protein of unknown function; Spider biofilm induced || 1 -0.65 -0.74 -0.31 -0.28 -0.23 0.45 -0.32 -0.66 0.23 -1.23 -0.66 0.06 -0.27 0.19 0.09 -0.52
8618 || orf19.6928 || SAP9 || || Secreted aspartyl protease; roles in adhesion, cell surface integrity; induced by antifungal drugs, stationary phase, or in white-phase cells; farnesol-downregulated in biofilm; autocatalytic processing; GPI-anchor; Spider biofilm induced || 1 -0.53 -0.57 -0.25 -0.12 0.09 -0.01 0.28 -0.71 -0.57 -0.74 -0.83 -0.12 -0.14 0.66 0.33 -0.01
8619 || orf19.5843 || SRR1 || || Two-component system response regulator; involved in stress response; Plc1-regulated; upregulated in cyr1 null mutant; flow model biofilm induced; Spider biofilm induced || 1 -1.52 -1.60 -0.65 0.63 -1.51 -0.32 -0.22 -3.84 -3.06 -1.42 -3.05 -1.23 0.12 0.37 1.08 -0.85
8620 || orf19.5843 || SRR1 || || Two-component system response regulator; involved in stress response; Plc1-regulated; upregulated in cyr1 null mutant; flow model biofilm induced; Spider biofilm induced || 1 -1.47 -1.56 -0.39 0.96 -1.63 -0.24 -0.22 -4.11 -2.56 -1.24 -3.14 -1.12 0.23 0.40 0.86 -0.84
8621 || orf19.1365 || || || Putative monooxygenase; mutation confers hypersensitivity to toxic ergosterol analog; constitutive expression independent of MTL or white-opaque status || 1 -0.42 -0.38 -0.11 0.18 -0.74 -0.30 -0.10 -0.95 -0.19 -1.15 -0.84 -0.43 0.18 0.24 -0.51 0.16
8622 || orf19.2023 || HGT7 || || Putative MFS glucose transporter; glucose, fluconazole, Snf3 induced, expressed at high glucose; 20 member C. albicans glucose transporter family; 12 TM regions predicted; flow model biofilm induced; Spider biofilm repressed || 1 -0.20 -0.09 0.25 -0.08 -0.35 -0.84 -0.06 -1.59 -1.40 -1.07 0.67 0.43 0.24 0.50
8623 || orf19.539 || LAP3 || || Putative aminopeptidase; positively regulated by Sfu1; clade-associated gene expression; virulence-group-correlated expression; induced by alpha pheromone in SpiderM medium; Hap43-induced; Spider and flow model biofilm induced || 1 -0.62 -0.67 -0.27 -1.25 -0.66 0.20 -1.00 -2.51 -0.44 -2.94 -2.91 -1.61 2.14 1.40 0.27 -0.31
8624 || orf19.539 || LAP3 || || Putative aminopeptidase; positively regulated by Sfu1; clade-associated gene expression; virulence-group-correlated expression; induced by alpha pheromone in SpiderM medium; Hap43-induced; Spider and flow model biofilm induced || 1 -0.93 -0.94 -0.11 -1.12 -0.94 0.17 -1.37 -2.85 0.04 -3.06 -2.88 -1.96 2.01 1.46 0.04 -0.54
8625 || orf19.100 || || || Alpha/beta hydrolase and lipase domain protein; Hap43-repressed; Spider and flow model biofilm induced || 1 -0.91 -0.95 0.13 -0.01 -0.12 0.13 -0.83 -1.35 -0.17 -1.29 -1.62 -0.68 0.66 0.58 -0.24 -0.00
8626 || orf19.7021 || GPH1 || || Putative glycogen phosphorylase; role in glycogen metabolism; regulated by Ssk1, Mig1, Tup1, Hap43; fluconazole-induced; localizes to cell surface of hyphae, not yeast; stationary phase enriched protein; Spider biofilm induced || 1 -0.73 -0.71 0.19 -0.30 -0.87 0.72 -0.50 -1.39 -0.37 -1.82 -1.51 -0.60 0.98 -0.28 0.06 -0.43
8627 || orf19.7021 || GPH1 || || Putative glycogen phosphorylase; role in glycogen metabolism; regulated by Ssk1, Mig1, Tup1, Hap43; fluconazole-induced; localizes to cell surface of hyphae, not yeast; stationary phase enriched protein; Spider biofilm induced || 1 -0.71 -0.92 0.16 -0.34 -0.46 1.26 -0.43 -1.25 -0.10 -1.69 -1.02 -0.12 0.68 -0.42 0.27 -0.29
8628 || orf19.675 || || || Cell wall protein; induced in core stress response and core caspofungin response; iron-regulated; amphotericin B, ketoconazole, and hypoxia induced; regulated by Cyr1, Ssn6; induced in oralpharyngeal candidasis; Spider biofilm repressed || 1 -0.77 -1.03 -0.38 0.15 -1.00 0.25 -0.12 -1.39 -0.95 -2.24 -1.01 -0.31 -0.09 0.75 0.05 -0.56
8629 || orf19.675 || || || Cell wall protein; induced in core stress response and core caspofungin response; iron-regulated; amphotericin B, ketoconazole, and hypoxia induced; regulated by Cyr1, Ssn6; induced in oralpharyngeal candidasis; Spider biofilm repressed || 1 -0.55 -0.64 -0.24 0.32 -0.68 0.34 -0.03 -1.36 -0.99 -2.24 -0.88 -0.38 0.12 0.60 0.26 -0.38
8630 || orf19.675 || || || Cell wall protein; induced in core stress response and core caspofungin response; iron-regulated; amphotericin B, ketoconazole, and hypoxia induced; regulated by Cyr1, Ssn6; induced in oralpharyngeal candidasis; Spider biofilm repressed || 1 -0.42 -0.55 -0.18 0.36 -0.58 0.34 -0.16 -1.30 -0.76 -2.24 -0.72 -0.41 0.26 0.54 0.19 -0.52
8631 || orf19.675 || || || Cell wall protein; induced in core stress response and core caspofungin response; iron-regulated; amphotericin B, ketoconazole, and hypoxia induced; regulated by Cyr1, Ssn6; induced in oralpharyngeal candidasis; Spider biofilm repressed || 1 -0.14 -0.07 0.25 0.60 -0.20 0.67 -0.11 -1.18 -0.44 -1.96 -0.74 -0.13 0.56 0.88 0.36 -0.22
8632 || orf19.3713 || || || Protein of unknown function; flow model biofilm induced; Spider biofilm induced; induced by Mnl1 under weak acid stress; transcript detected in high-resolution tiling arrays || 1 -0.46 -0.57 0.01 0.07 0.03 0.57 -0.15 -0.70 -0.87 -1.54 -0.08 -0.72 0.36 0.25 0.34 0.25
8633 || orf19.4843 || || || Putative iron/copper reductas; involved in iron homeostasis; rat catheter and Spider biofilm induced || 1 -0.56 -0.68 -0.13 -0.25 0.35 -0.07 -0.13 -0.78 -0.43 -0.67 -0.63 -0.89 0.23 0.54 -0.12 0.05
8634 || orf19.5869 || || || Ortholog(s) have role in metal ion transport, protein targeting to vacuole, ubiquitin-dependent protein catabolic process and endoplasmic reticulum, fungal-type vacuole membrane localization || 1 -0.43 -0.67 -0.57 -0.51 -0.53 -0.44 0.05 -0.33 -0.50 -0.34 -0.49 -0.11 0.12 0.22 0.56 0.09
8635 || orf19.7393 || || || Predicted NAD+/NADH kinase; possible role in cellular iron ion homeostasis; Spider biofilm induced || 1 -0.74 -0.98 -1.07 -0.72 -0.68 -0.27 -0.28 -0.74 -0.62 -0.26 -0.30 0.12 0.06 0.10 1.02 0.13
8636 || orf19.7393 || || || Predicted NAD+/NADH kinase; possible role in cellular iron ion homeostasis; Spider biofilm induced || 1 -0.70 -0.82 -0.99 -0.71 -0.64 -0.39 -0.44 -0.71 -0.38 0.03 -0.30 0.03 0.12 0.12 0.70 -0.03
8637 || orf19.3670 || GAL1 || || Galactokinase; galactose, Mig1, Tup1, Hap43 regulated; fluconazole, ketoconazole-induced; stationary phase enriched protein; GlcNAc-induced protein; farnesol, hypoxia-repressed in biofilm; rat catheter and Spider biofilm induced || 1 -1.92 -1.91 -0.87 -0.66 -1.29 -0.52 -1.50 -1.21 -0.25 -0.06 -1.81 0.10 -0.20 0.82 2.37 0.03
8638 || orf19.3670 || GAL1 || || Galactokinase; galactose, Mig1, Tup1, Hap43 regulated; fluconazole, ketoconazole-induced; stationary phase enriched protein; GlcNAc-induced protein; farnesol, hypoxia-repressed in biofilm; rat catheter and Spider biofilm induced || 1 -2.42 -2.30 -1.60 -1.08 -1.20 -0.93 -1.57 -1.25 -0.68 -0.42 -1.79 -0.20 -0.49 0.74 2.10 -0.32
8639 || orf19.3675 || GAL7 || || Putative galactose-1-phoshphate uridyl transferase; downregulated by hypoxia, upregulated by ketoconazole; macrophage/pseudohyphal-repressed || 1 -2.89 -2.62 -1.18 -0.28 -2.93 -1.79 -1.51 -1.19 -0.90 -0.31 -1.71 -1.16 -0.44 0.81 1.45 -0.70
8640 || orf19.3675 || GAL7 || || Putative galactose-1-phoshphate uridyl transferase; downregulated by hypoxia, upregulated by ketoconazole; macrophage/pseudohyphal-repressed || 1 -1.62 -1.58 -0.71 -0.14 -1.75 -1.17 -0.79 -0.70 -0.67 -0.15 -1.18 -0.77 -0.15 1.26 1.95 -0.58
8641 || orf19.1191 || || || Ortholog(s) have ubiquitin-protein ligase activity and role in ER-associated ubiquitin-dependent protein catabolic process || 1 -0.31 -0.45 -0.29 -0.06 -0.14 -0.28 -0.30 -0.21 -0.10 0.08 -0.36 -0.26 -0.29 0.16 0.22 -0.19
8642 || orf19.1591 || ERG10 || || Acetyl-CoA acetyltransferase; role in ergosterol biosynthesis; soluble in hyphae; changes in protein abundance associated with azole resistance; fluconazole or ketoconazole induced; macrophage-downregulated protein; GlcNAc-induced protein || 1 -0.14 -0.45 -0.23 -0.16 -0.21 -0.22 -0.31 -0.35 0.16 -0.09 -0.31 -0.23 -0.04 -0.08 0.45 0.12
8643 || orf19.441 || RPT1 || || Putative 26S proteasome regulatory subunit 7; Hap43p-repressed gene; regulated by Gcn2p and Gcn4p; overlaps orf19.442 || 1 -0.41 -0.61 0.06 -0.40 -0.41 -0.36 -0.15 -0.18 0.05 0.03 -0.15 0.10 -0.49 -0.15 0.43 0.18
8644 || orf19.3773 || CDL1 || || Putative RNAse III, ortholog of S. cerevisiae RNT1; merged with orf19.3772 in Assembly 21 || 1 -0.66 -0.92 0.02 -0.46 -0.59 -0.27 -0.10 -0.13 0.10 0.08 -0.20 -0.14 -0.23 0.14 0.14 0.02
8645 || orf19.5931 || ARV1 || || Lipid transporter involved in sterol trafficking and transport of glycosylphosphatidylinositol and sphingolipid precursors || 1 -0.71 -1.16 -0.05 -0.49 -0.55 -0.44 0.00 -0.30 0.24 0.14 -0.44 -0.06 -0.29 -0.01 -0.07 -0.11
8646 || orf19.4028 || || || Putative cis-prenyltransferase involved in dolichol synthesis; participates in endoplasmic reticulum (ER) protein sorting; flow model biofilm induced || 1 -0.52 -0.43 0.10 -0.16 -0.43 -0.39 -0.37 -0.19 0.37 0.37 -0.49 0.02 0.04 0.20 -0.12 -0.18
8647 || orf19.31 || || || Ortholog of C. parapsilosis CDC317 : CPAR2_201960, C. dubliniensis CD36 : Cd36_20900, Candida tropicalis MYA-3404 : CTRG_04756 and Candida albicans WO-1 : CAWG_04394 || 1 -0.52 -0.64 0.19 -0.04 -0.95 -0.85 -0.37 -0.21 0.66 -0.13 -0.60 -0.04 0.21 0.57 -0.49 0.03
8648 || orf19.4668 || || || Protein with a glycoside hydrolase domain; mutants are viable || 1 -1.38 -1.26 -0.26 -0.39 -1.25 -1.15 -0.56 -0.34 -0.01 -0.09 -0.50 0.14 0.91 0.90 -0.71 -0.99
8649 || orf19.642 || || || Ortholog of C. dubliniensis CD36 : Cd36_30470, C. parapsilosis CDC317 : CPAR2_203380, Candida tenuis NRRL Y-1498 : CANTEDRAFT_117493 and Debaryomyces hansenii CBS767 : DEHA2G19228g || 1 -0.00 -0.04 -0.18 -0.26 -0.48 -0.44 -0.28 -0.05 0.06 -0.11 -0.17 0.05 0.08 0.17 -0.20 -0.26
8650 || orf19.3436 || || || Protein with a Rho GDP-dissociation inhibitor domain; macrophage-induced gene || 1 -0.14 -0.08 0.08 -0.29 -0.48 -0.90 -0.38 -0.02 0.03 -0.19 -0.29 -0.09 0.00 0.24 -0.42 -0.17
8651 || orf19.4668 || || || Protein with a glycoside hydrolase domain; mutants are viable || 1 -0.22 -0.18 0.12 -0.12 -0.47 -0.64 -0.26 0.19 0.12 -0.14 -0.45 0.16 0.44 0.32 -0.42 -0.56
8652 || orf19.4337 || || || Predicted membrane transporter; monocarboxylate porter (MCP) family, major facilitator superfamily (MFS); Spider biofilm induced; rat catheter biofilm repressed || 1 -0.23 -0.09 -0.12 -0.06 -0.96 -0.90 0.20 -0.36 0.07 -0.75 -0.80 -0.03 0.59 0.45 -0.61 -0.66
8653 || orf19.4649 || ZCF27 || || Putative Zn(II)2Cys6 transcription factor || 1 -0.62 -0.57 0.09 -0.36 -1.10 -0.21 -0.49 -0.38 0.11 -0.11 -1.26 -0.05 1.32 0.11 -1.38 -1.43
8654 || orf19.1942 || SGE1 || || Putative multidrug resistance factor; induced in low iron; regulated by Sef1, Sfu1, and Hap43 || 1 -0.20 -0.48 0.30 -0.05 -0.24 -0.28 -0.25 -0.52 -0.33 -0.31 -1.12 -0.51 0.21 0.34 -0.25 0.02
8655 || orf19.4936 || || || Dubious open reading frame || 1 -0.65 -0.47 -0.27 0.16 -0.43 -0.32 -0.03 -0.14 -0.81 -0.64 -0.98 -0.15 0.30
8656 || orf19.675 || || || Cell wall protein; induced in core stress response and core caspofungin response; iron-regulated; amphotericin B, ketoconazole, and hypoxia induced; regulated by Cyr1, Ssn6; induced in oralpharyngeal candidasis; Spider biofilm repressed || 1 -0.60 -0.70 -0.30 0.36 -0.97 -0.17 0.10 -0.69 -0.47 -0.88 -0.79 -0.35 0.18 0.29 0.00 -0.68
8657 || orf19.2049 || || || Plasma membrane-associated protein; heterozygous null mutant displays sensitivity to virgineone; Spider biofilm induced || 1 -0.95 -0.94 -0.47 0.43 -1.62 -1.35 0.77 -1.56 -1.59 -1.39 -2.08 -1.79 -0.30 0.99 -0.69 -0.64
8658 || orf19.2049 || || || Plasma membrane-associated protein; heterozygous null mutant displays sensitivity to virgineone; Spider biofilm induced || 1 -1.31 -1.28 -0.69 -0.22 -1.95 -1.54 0.46 -1.68 -1.93 -1.37 -2.39 -1.55 -0.97 0.98 -1.03 -0.58
8659 || orf19.551 || || || Ortholog of C. dubliniensis CD36 : Cd36_29980, C. parapsilosis CDC317 : CPAR2_204170, Candida tenuis NRRL Y-1498 : CANTEDRAFT_110235 and Debaryomyces hansenii CBS767 : DEHA2F17072g || 1 -0.43 -0.43 -0.02 0.04 -0.44 -0.37 -0.01 -0.28 -0.18 -0.00 -0.42 -0.25 0.10 0.33 -0.25 -0.07
8660 || orf19.2182 || BLM3 || || Putative proteasome activator; binds core proteasome and stimulates proteasome-mediated protein degradation by inducing gate opening; ortholog of S. cerevisiae Blm10; transcript regulated by Nrg1 and Mig1 || 1 -0.87 -0.91 -0.78 -1.22 -1.08 -1.21 -0.05 -0.22 0.30 -0.58 -1.11 -1.00 1.44 1.26 -0.51 -0.99
8661 || orf19.101 || RIM9 || || Protein required for alkaline pH response via the Rim101 signaling pathway; ortholog of S. cerevisiae Rim9 and A. nidulans palI; Spider biofilm induced || 1 -1.28 -1.37 -0.63 -0.88 -1.00 -1.20 -0.63 -0.69 -0.05 -0.55 -1.55 -1.30 1.67 1.42 -1.06 -0.72
8662 || orf19.4649 || ZCF27 || || Putative Zn(II)2Cys6 transcription factor || 1 -1.10 -1.06 -0.97 -1.28 -1.27 -0.67 -0.52 -0.51 0.06 -0.10 -1.47 -0.86 1.13 -0.12 -1.54 -0.77
8663 || orf19.4281 || || || Transcription factor; forms a heterodimer with Fhl11 that is tethered to promoters by Tbf1; positively regulates rRNA and ribosomal protein gene transcription; merged with orf19.4282; Spider biofilm induced || 1 -0.87 -0.96 -0.87 -1.07 -1.35 -0.95 -0.56 -0.35 -0.25 -0.06 -1.43 -1.45 0.66 0.47 -0.76 -1.39
8664 || orf19.1945 || AUR1 || || Inositolphosphorylceramide (IPC) synthase; catalyzes the key step in sphingolipid biosynthesis; antifungal drug target; flow model biofilm induced; Spider biofilm induced || 1 -1.22 -1.33 -0.91 -0.57 -1.23 -0.70 0.41 -0.66 0.04 -0.39 -1.49 -1.25 0.54 0.77 -0.80 -1.05
8665 || orf19.1945 || AUR1 || || Inositolphosphorylceramide (IPC) synthase; catalyzes the key step in sphingolipid biosynthesis; antifungal drug target; flow model biofilm induced; Spider biofilm induced || 1 -1.47 -1.59 -1.23 -1.16 -1.35 -0.79 0.17 -0.88 -0.42 -0.88 -1.57 -1.10 0.14 0.79 -0.82 -0.72
8666 || orf19.3753 || SEF1 || || Zn2-Cys6 transcription factor; regulates iron uptake; negatively regulated by Sfu1p, positively regulated by Tbf1; promotes virulence in mice; mutants display decreased colonization of mouse kidneys; Spider biofilm induced || 1 -1.09 -1.25 -1.71 -0.69 -0.35 -1.35 -0.22 -0.45 -0.90 -0.73 -0.99 -1.20 1.18 0.94 -0.37 -0.40
8667 || orf19.3753 || SEF1 || || Zn2-Cys6 transcription factor; regulates iron uptake; negatively regulated by Sfu1p, positively regulated by Tbf1; promotes virulence in mice; mutants display decreased colonization of mouse kidneys; Spider biofilm induced || 1 -0.70 -1.11 -0.62 -0.25 -0.64 -0.53 -0.40 -0.72 -0.79 -0.58 -1.07 -0.67 1.37 1.06 -0.66 -0.39
8668 || orf19.233.1 || HRT1 || || Ortholog of S. cerevisiae Hrt1; component of a nuclear ubiquitin-protein ligase complex involved in cell cycle control; induced by hydroxyurea; Spider biofilm induced || 1 -0.46 -0.31 -0.31 -0.26 -0.55 -0.79 -0.61 -0.46 -0.37 -0.05 -0.60 -0.50 0.63 0.07 -0.02 -0.12
8669 || orf19.1277 || || || Protein of unknown function; Rgt1, Hap43-repressed; flow model biofilm induced; Spider biofilm induced || 1 -0.38 -0.38 0.33 0.65 -0.95 -1.49 -0.59 -1.09 -0.14 -0.20 -2.48 -1.53 0.91 0.29 1.01 -0.53
8670 || orf19.1277 || || || Protein of unknown function; Rgt1, Hap43-repressed; flow model biofilm induced; Spider biofilm induced || 1 -0.72 -0.70 0.31 0.49 -1.42 -1.55 -0.76 -1.17 0.12 -0.05 -2.25 -1.62 0.73 0.75 0.74 -0.93
8671 || orf19.1277 || || || Protein of unknown function; Rgt1, Hap43-repressed; flow model biofilm induced; Spider biofilm induced || 1 -1.17 -1.16 0.08 0.37 -3.32 -2.39 -1.15 -1.76 -0.37 -0.14 -3.89 -1.86 0.86 0.52 0.72 -0.94
8672 || orf19.1277 || || || Protein of unknown function; Rgt1, Hap43-repressed; flow model biofilm induced; Spider biofilm induced || 1 -1.19 -1.32 0.14 0.28 -3.65 -2.86 -1.27 -1.81 -0.16 -0.06 -4.84 -1.99 0.68 0.30 0.48 -1.58
8673 || orf19.1727 || PMC1 || || Vacuolar calcium P-type ATPase; transcript regulated by calcineurin and fluconazole; mutant shows increased resistance to fluconazole, lithium; increased sensitivity to calcium; Spider biofilm induced || 1 -0.44 -0.57 -0.17 0.02 -1.38 -0.96 -0.20 -1.47 -0.69 -0.56 -1.14 -0.73 -0.02 0.05 0.07 -0.58
8674 || orf19.1277 || || || Protein of unknown function; Rgt1, Hap43-repressed; flow model biofilm induced; Spider biofilm induced || 1 -0.93 -0.95 -0.56 -0.09 -1.20 -1.32 -1.17 -1.84 -0.60 -0.43 -1.77 -1.77 0.46 -0.12 -0.15 -0.64
8675 || orf19.2432 || HAC1 || || bZIP transcription factor; role in unfolded protein response and control of morphology; transcript undergoes atypical splicing at C terminus under ER stress; induced during mating and by caspofungin; mRNA binds She3; Spider biofilm induced || 1 -0.37 -0.55 0.02 -0.26 -0.49 -0.24 -0.24 -1.07 -0.24 -0.15 -1.36 -0.58 0.29 -0.14 0.13 -0.29
8676 || orf19.2038 || || || Protein of unknown function; Spider biofilm induced || 1 -1.66 -2.31 -1.15 -0.62 -1.83 -0.72 -1.72 -2.99 -0.55 -0.80 -2.89 -1.73 2.48 1.88 0.86 -0.51
8677 || orf19.2038 || || || Protein of unknown function; Spider biofilm induced || 1 -1.74 -2.02 0.47 -0.47 -1.66 -0.61 -2.21 -2.10 -1.06 -1.42 -2.37 -1.98 2.37 1.54 0.82 -1.34
8678 || orf19.3794 || CSR1 || || Transcription factor; role in zinc homeostasis and regulation of Spider biofilm matrix; mutation affects filamentous growth; can suppress S. cerevisiae rok1 mutant inviability; Spider biofilm induced; mutants for abnormal Spider biofilms || 1 -0.80 -0.77 -0.57 -1.10 -2.05 -2.42 -1.10 -1.77 -1.20 -1.74 -2.54 -2.45 2.25 1.54 0.03 -1.83
8679 || orf19.1585 || ZRT2 || || Zinc transporter; ciclopirox olamine, fluconazole, alkaline repressed; transcript induced by amphotericin B, interaction with macrophages; possibly essential (UAU1 method); induced in oralpharyngeal candidiasis; Spider biofilm induced || 1 -2.05 -2.25 -0.71 -2.11 -3.53 -2.79 -1.66 -2.07 -0.57 -2.41 -3.02 -2.77 1.31 -0.04 -0.98
8680 || orf19.1585 || ZRT2 || || Zinc transporter; ciclopirox olamine, fluconazole, alkaline repressed; transcript induced by amphotericin B, interaction with macrophages; possibly essential (UAU1 method); induced in oralpharyngeal candidiasis; Spider biofilm induced || 1 -1.83 -1.88 -0.41 -1.37 -2.78 -2.38 -1.44 -1.88 -0.18 -2.21 -2.63 -2.29 1.87 0.28 -0.78
8681 || orf19.3672 || GAL10 || || UDP-glucose 4-epimerase; galactose utilization; mutant has cell wall defects and increased filamentation; GlcNAc-, fluconazole- and ketoconazole-induced; stationary phase enriched protein; rat catheter and flow model biofilm induced || 1 -1.13 -1.16 -0.80 -1.29 -2.32 -1.83 -0.71 -1.08 -0.40 -1.35 -3.17 -2.05 0.89 1.11 0.97 -1.90
8682 || orf19.3672 || GAL10 || || UDP-glucose 4-epimerase; galactose utilization; mutant has cell wall defects and increased filamentation; GlcNAc-, fluconazole- and ketoconazole-induced; stationary phase enriched protein; rat catheter and flow model biofilm induced || 1 -1.28 -1.33 -0.74 -1.14 -2.40 -1.50 -0.63 -1.06 -0.46 -1.13 -3.05 -1.38 0.98 1.36 1.25 -1.43
8683 || orf19.3672 || GAL10 || || UDP-glucose 4-epimerase; galactose utilization; mutant has cell wall defects and increased filamentation; GlcNAc-, fluconazole- and ketoconazole-induced; stationary phase enriched protein; rat catheter and flow model biofilm induced || 1 -0.96 -0.86 -0.20 -0.48 -1.90 -1.38 -0.63 -0.93 -0.00 -0.95 -2.63 -1.42 1.06 1.25 1.57 -1.19
8684 || orf19.3672 || GAL10 || || UDP-glucose 4-epimerase; galactose utilization; mutant has cell wall defects and increased filamentation; GlcNAc-, fluconazole- and ketoconazole-induced; stationary phase enriched protein; rat catheter and flow model biofilm induced || 1 -1.12 -0.96 -0.24 -0.41 -1.92 -1.13 -0.56 -0.74 -0.10 -1.10 -2.61 -1.08 1.20 1.46 1.47 -0.96
8685 || orf19.3672 || GAL10 || || UDP-glucose 4-epimerase; galactose utilization; mutant has cell wall defects and increased filamentation; GlcNAc-, fluconazole- and ketoconazole-induced; stationary phase enriched protein; rat catheter and flow model biofilm induced || 1 -0.84 -0.77 0.01 -0.37 -1.94 -1.11 -0.38 -0.66 0.14 -0.69 -2.61 -0.93 1.38 1.64 1.45 -1.25
8686 || orf19.6273 || || || Ortholog of C. dubliniensis CD36 : Cd36_05960, C. parapsilosis CDC317 : CPAR2_301790, Candida tenuis NRRL Y-1498 : CANTEDRAFT_112420 and Debaryomyces hansenii CBS767 : DEHA2G15290g || 1 -0.29 -0.27 -0.35 -0.14 -0.17 -0.48 -0.35 0.07 -0.26 -0.31 -0.08 0.05 0.07 -0.03 0.12 -0.33
8687 || orf19.3436 || || || Protein with a Rho GDP-dissociation inhibitor domain; macrophage-induced gene || 1 -0.45 -0.36 -0.28 -0.36 -0.50 -1.03 -0.43 -0.26 -0.47 -0.79 -0.56 -0.24 0.07 -0.07 -0.38 -0.26
8688 || orf19.7125 || || || Protein of unknown function; Spider biofilm repressed || 1 -0.22 -0.29 -0.13 -0.03 -0.41 -0.91 -0.39 -0.17 -0.26 -0.56 -0.43 -0.06 -0.19 -0.19 -0.14 -0.32
8689 || orf19.7585 || INO1 || || Inositol-1-phosphate synthase; antigenic in human; repressed by farnesol in biofilm or by caspofungin; upstream inositol/choline regulatory element; glycosylation predicted; rat catheter, flow model induced; Spider biofilm repressed || 1 -1.15 -1.08 -1.24 -0.16 -2.58 -3.04 -0.94 -1.29 -1.32 -0.87 -2.06 0.18 1.12 0.90 1.57 0.79
8690 || orf19.7585 || INO1 || || Inositol-1-phosphate synthase; antigenic in human; repressed by farnesol in biofilm or by caspofungin; upstream inositol/choline regulatory element; glycosylation predicted; rat catheter, flow model induced; Spider biofilm repressed || 1 -1.31 -1.30 -1.21 0.11 -2.74 -3.44 -1.28 -1.49 -1.60 -1.08 -2.25 -0.23 0.95 0.38 1.13 0.32
8691 || orf19.6285 || GLC7 || || Putative catalytic subunit of type 1 serine/threonine protein phosphatase; regulated by Shp1; induced in high iron; alternatively spliced intron in 5' UTR || 1 -0.19 -0.26 -0.31 -0.08 -0.78 -0.55 -0.38 -0.17 -0.51 -0.25 -0.10 -0.06 -0.01 0.03 0.10 -0.08
8692 || orf19.6285 || GLC7 || || Putative catalytic subunit of type 1 serine/threonine protein phosphatase; regulated by Shp1; induced in high iron; alternatively spliced intron in 5' UTR || 1 -0.23 -0.28 -0.21 0.10 -0.94 -0.76 -0.40 -0.02 -0.43 0.00 -0.14 -0.23 -0.02 -0.07 -0.06 -0.23
8693 || orf19.3010.1 || ECM33 || || GPI-anchored cell wall protein; mutants show cell-wall defects and reduced adhesion, host cell damage, and endocytosis; mutant infection is immunoprotective in murine model; fluconazole-induced; caspofungin repressed || 1 -0.25 -0.31 -0.33 0.44 -1.58 -0.87 -0.11 -0.34 -0.46 -0.17 -0.25 -0.05 -0.03 -0.48 0.41 0.12
8694 || orf19.1850 || SIW14 || || Putative protein phosphatase of the PTP family (tyrosine-specific), similar to S. cerevisiae Siw14p; mutant shows virulence defect; Hap43p-repressed gene || 1 -0.22 -0.28 -0.13 -0.40 -0.47 -0.44 -0.10 -0.45 -0.08 -0.32 0.06 -0.01 0.12 -0.16 -0.31 -0.24
8695 || orf19.4377 || KRE1 || || Cell wall glycoprotein; beta glucan synthesis; increases glucan content in S. cerevisiae kre1, complements killer toxin sensitivity; caspofungin induced; Spider/rat catheter/flow model biofilm induced; Bcr1-repressed in RPMI a/a biofilms || 1 -0.74 -0.73 -0.60 -0.86 -1.22 0.05 -0.70 -1.55 -1.33 -2.12 -0.28 1.11 0.73 -0.34 -0.17 -1.10
8696 || orf19.5869 || || || Ortholog(s) have role in metal ion transport, protein targeting to vacuole, ubiquitin-dependent protein catabolic process and endoplasmic reticulum, fungal-type vacuole membrane localization || 1 -0.41 -0.66 -0.18 -0.12 -0.62 -0.34 -0.16 -0.37 -0.30 -0.21 -0.31 -0.22 0.31 -0.53 0.39 0.01
8697 || orf19.4843 || || || Putative iron/copper reductas; involved in iron homeostasis; rat catheter and Spider biofilm induced || 1 -0.58 -0.30 0.43 -0.02 0.17 -0.07 -0.33 -0.61 0.29 -0.49 -0.60 -0.82 0.11 0.30 -0.33 -0.34
8698 || orf19.1341 || PRR2 || || Putative serine/threonine protein kinase; mutation confers resistance to 5-fluorocytosine (5-FC) || 1 -0.38 -0.20 0.47 -0.15 0.03 -0.38 -0.52 -0.50 0.32 -0.67 -0.51 -0.12 0.15 -0.01 -0.70 0.02
8699 || orf19.4819 || || || Protein of unknown function; transcript detected on high-resolution tiling arrays; rat catheter biofilm induced || 1 -0.80 -0.97 -0.19 -0.02 0.04 -1.03 -0.47 -0.77 0.02 -0.31 -1.15 -0.12 0.32 -1.36
8700 || orf19.2910 || PGA43 || || Putative GPI-anchored protein || 1 -0.46 -0.48 -0.47 -0.21 -0.03 -0.40 -0.18 -0.11 0.14 -0.43 -0.31 -0.32 0.12 -0.04 -0.47 -0.03
8701 || orf19.570 || IFF8 || || Putative GPI-anchored adhesin-like protein; decreased transcription is observed in an azole-resistant strain that overexpresses MDR1 || 1 -0.20 -0.33 0.34 -0.17 -0.79 -1.01 -1.25 -1.27 -1.13 -0.93 -1.41 -0.30 0.65 -0.83 -0.66 0.35
8702 || orf19.2496 || ATO2 || || Putative fungal-specific transmembrane protein; fluconazole repressed, Hap43-repressed; flow model biofilm induced; Spider biofilm induced || 1 -0.83 -0.82 0.32 0.72 -0.88 -0.77 -1.34 -0.35 -1.72 0.17 0.06 -1.15 -0.82 -1.21 -0.56 0.65
8703 || orf19.2496 || ATO2 || || Putative fungal-specific transmembrane protein; fluconazole repressed, Hap43-repressed; flow model biofilm induced; Spider biofilm induced || 1 -1.21 -1.53 -0.57 0.05 -1.50 -1.21 -1.29 -0.58 -2.01 0.24 -0.16 -1.12 -1.17 -0.84 -0.47 0.48
8704 || orf19.2075 || DFG5 || || N-linked mannoprotein of cell wall and membrane; possible signal transducer; role in hyphal growth and HWP1 induction in alkaline pH; GPI modification predicted; dfg5 dcw1 double mutant is inviable; caspofungin-induced, fungal-specific || 1 -0.40 -0.44 0.01 -0.00 -0.18 -0.50 -0.52 -0.22 -0.29 -0.15 -0.20 -0.50 -0.45 -0.30 -0.54 0.13
8705 || orf19.5588 || PGA60 || || Putative GPI-anchored adhesin-like protein; hyphal-induced expression || 1 -0.48 -0.58 -0.21 -0.11 -0.54 -0.82 -0.42 -0.60 -0.32 0.36 -0.87 -0.52 -0.77 0.21 -0.37 0.44
8706 || orf19.2680 || || || Ortholog(s) have phospholipid-translocating ATPase activity, role in intracellular protein transport, phospholipid translocation and trans-Golgi network transport vesicle localization || 1 -0.22 -0.26 -0.12 0.13 -0.31 -0.32 -0.53 -0.44 -0.41 -0.10 -0.32 -0.38 -0.20 0.16 -0.03 0.15
8707 || orf19.6211 || || || Protein of unknown function; protein newly produced during adaptation to the serum || 1 -0.43 -0.64 0.28 0.70 0.15 -1.40 -0.94 -0.42 -0.70 0.04 -0.39 -0.62 -1.26 0.19 -0.87 -0.05
8708 || orf19.6211 || || || Protein of unknown function; protein newly produced during adaptation to the serum || 1 -0.32 -0.40 0.39 0.79 0.20 -1.56 -0.88 -0.09 -0.60 -0.03 -0.22 -0.87 -0.98 -0.22 -0.69 -0.22
8709 || orf19.2237 || SPR1 || || Putative GPI-anchored protein; similar but not orthologous to S. cerevisiae Spr1, a sporulation-specific exo-1,3-beta-glucanase; mutant is viable || 1 -0.17 -0.57 -0.17 -0.07 0.13 -0.85 -0.27 -0.05 -0.41 -0.19 -0.81 -0.04 -0.70 -0.55 -0.43 0.04
8710 || orf19.3734 || GEF2 || || Member of the voltage chloride channel family; Hap43p-repressed gene || 1 -0.37 -0.27 0.17 0.25 -0.48 -0.68 -0.37 -0.41 0.04 -0.12 -0.94 -0.13 -0.66 0.01 -0.47 0.37
8711 || orf19.5588 || PGA60 || || Putative GPI-anchored adhesin-like protein; hyphal-induced expression || 1 -0.21 -0.26 0.32 0.26 -0.64 -1.26 -0.06 -0.31 -0.06 -0.13 -0.98 -0.26 -0.82 -0.27 -1.14 0.05
8712 || orf19.7606 || || || Ortholog of C. dubliniensis CD36 : Cd36_35262, Candida tropicalis MYA-3404 : CTRG_05848 and Candida albicans WO-1 : CAWG_02290 || 1 -0.34 -0.22 0.32 0.35 -0.88 -1.22 -0.51 -0.25 0.06 -0.05 -0.67 -0.36 -0.44 0.25 -1.00 0.10
8713 || orf19.4481 || MFALPHA || || Alpha factor mating pheromone precursor; three copies of pheromone that are proteolytically processed by Kex2p and possibly by Orf19.5851p; required for alpha cells to mate; expressed specifically in opaque phase MTLalpha/MTLalpha cells || 1 -0.43 -0.12 0.09 0.31 -0.14 -1.14 -0.51 -0.43 -0.20 0.12 -0.67 0.01 -0.12 -0.03 -1.36 0.13
8714 || orf19.5042 || || || Ortholog(s) have role in maintenance of rDNA and nuclear periphery localization || 1 -0.17 -0.05 0.05 0.05 -0.32 -1.11 -0.47 -0.48 0.25 0.09 -0.37 0.15 -0.50 0.07 -0.62 -0.29
8715 || orf19.2478 || || || Ortholog of C. dubliniensis CD36 : Cd36_05410, C. parapsilosis CDC317 : CPAR2_107480, Candida tenuis NRRL Y-1498 : CANTEDRAFT_94695 and Debaryomyces hansenii CBS767 : DEHA2D02288g || 1 -0.32 -0.33 0.17 -0.11 -0.18 -0.75 -0.50 -0.10 0.01 0.08 -0.47 0.20 -0.18 -0.39 -0.60 -0.16
8716 || orf19.1124 || || || Protein of unknown function; flow model biofilm induced; Spider biofilm induced || 1 -0.12 0.16 0.65 0.08 -0.56 -1.14 -0.58 -0.93 -0.23 -0.14 -1.05 0.56 -0.22 -0.92 -0.19 -0.14
8717 || orf19.3621 || || || Possible pseudogene; similar to Ywp1p; ORF extended upstream from the initiating Met of orf19.3621 has a stop codon in the region corresponding to the Ywp1p signal peptide; disruption causes no apparent phenotype; no expression detected || 1 0.48 -0.15 0.14 -0.06 -0.64 -1.45 -0.63 -0.87 -0.50 0.24 -1.18 0.28 -0.76 -1.12 -0.23 0.22
8718 || orf19.7447 || JEN1 || || Lactate transporter; induced by lactic acid, activated by Cat8; alkaline repressed by Rim101; localizes to plasma membrane; Spider biofilm induced || 1 0.34 0.17 -0.10 1.36 -1.31 -1.80 -0.55 -0.94 -0.31 0.66 -1.71 0.06 -0.62 -2.03 -0.53 -0.39
8719 || orf19.6993 || GAP2 || || General amino acid permease; ketoconazole, flucytosine repressed; Ssy1-dependent histidine induction; regulated by Nrg1, Tup1; colony morphology-related gene regulation by Ssn6; Spider and flow model biofilm induced || 1 -0.58 -0.56 0.08 0.80 -0.61 -1.71 -0.41 -1.11 0.01 0.43 -2.18 -0.87 -0.72 -1.03 -0.54 -0.37
8720 || orf19.6993 || GAP2 || || General amino acid permease; ketoconazole, flucytosine repressed; Ssy1-dependent histidine induction; regulated by Nrg1, Tup1; colony morphology-related gene regulation by Ssn6; Spider and flow model biofilm induced || 1 -0.81 -0.55 -0.03 0.33 -0.79 -1.99 -0.37 -1.05 -0.42 0.19 -2.25 -1.09 -0.82 -1.08 -0.32 0.09
8721 || orf19.815 || DCK1 || || Putative guanine nucleotide exchange factor; required for embedded filamentous growth; activates Rac1; has a DOCKER domain; similar to adjacent DCK2 and to S. cerevisiae Ylr422wp; regulated by Nrg1; Spider biofilm induced || 1 0.22 0.15 -0.19 0.07 -0.06 -0.92 -0.48 -0.66 0.19 0.17 -0.59 -0.51 -0.07 -0.61 -0.28 -0.37
8722 || orf19.3738 || PGA22 || || Putative GPI-anchored protein; adhesin-like protein || 1 0.19 0.21 0.02 0.54 -0.07 -0.94 -0.53 -0.18 -0.53 -0.49 -0.46 -0.57 -0.42 -0.55 -0.31 -0.06
8723 || orf19.6911 || || || Ortholog of Candida albicans WO-1 : CAWG_05482 || 1 -0.40 0.04 0.36 0.86 -0.36 -0.50 -0.86 -0.47 -0.18 -0.71 -0.72 -0.32 -0.63 -0.86 -0.72 -0.73
8724 || orf19.2350 || || || Protein similar to S. cerevisiae Yor378w; MFS family transporter; transposon mutation affects filamentous growth; null mutants are viable; fungal-specific (no human or murine homolog) || 1 0.11 -0.08 0.28 1.10 -0.33 -0.61 -0.46 -0.30 -0.36 -0.82 -0.80 -0.16 -0.12 -0.55 -0.35 -0.46
8725 || orf19.6626 || || || Predicted homeodomain-containing protein; possible transcription factor; possibly transcriptionally regulated upon hyphal formation || 1 0.02 -0.17 -0.01 0.35 -0.08 -0.50 -0.49 -0.29 0.01 -0.76 -0.44 -0.43 0.04 -0.30 -0.38 -0.38
8726 || orf19.3713 || || || Protein of unknown function; flow model biofilm induced; Spider biofilm induced; induced by Mnl1 under weak acid stress; transcript detected in high-resolution tiling arrays || 1 -0.60 -0.42 -0.05 0.17 -0.35 -0.73 -0.22 0.06 -0.56 -1.01 -0.59 -0.59 -0.46 -0.91 -0.20 -0.73
8727 || orf19.3760 || DLH1 || || Functional homolog of S. cerevisiae Dmc1; a meiosis-specific protein required for repair of double-strand breaks and pairing between homologous chromosomes || 1 -0.46 -0.52 -0.36 0.39 -0.95 -1.72 -0.69 -0.86 -1.44 -1.20 -0.99 -0.43 -0.40 -1.12 -0.68 -0.91
8728 || orf19.4962 || RMP1 || || Ortholog of Rmp1; subunit of RNase MRP subunit that processes pre-rRNA and has a role in cell cycle-regulated degradation of daughter cell-specific mRNAs; rat catheter and Spider biofilm induced || 1 0.05 -0.04 0.17 0.36 -0.20 -1.21 -0.70 -0.47 -0.57 -1.22 -0.48 -0.61 -0.07 -1.15 -0.40 -0.69
8729 || orf19.6777 || || || Ortholog of Candida albicans WO-1 : CAWG_03032 || 1 0.03 -0.17 -0.09 0.30 0.14 -0.82 -0.68 -0.35 -0.72 -1.06 -0.44 -0.17 -0.27 -0.47 -0.17 -0.38
8730 || orf19.2986 || || || Ortholog of C. dubliniensis CD36 : Cd36_02750, C. parapsilosis CDC317 : CPAR2_106015, Candida tenuis NRRL Y-1498 : CANTEDRAFT_107500 and Debaryomyces hansenii CBS767 : DEHA2D08250g || 1 -0.11 -0.47 0.31 0.54 -0.19 -0.51 -0.56 -0.23 -0.50 -0.63 -0.55 -0.41 -0.22 -0.55 0.07 -0.06
8731 || orf19.331 || || || Ortholog(s) have S-adenosylmethionine-dependent methyltransferase activity, protein methyltransferase activity and role in peptidyl-glutamine methylation, regulation of translation || 1 -0.29 -0.26 0.69 0.11 -0.24 -0.70 -0.70 -0.56 -0.55 -0.96 -0.87 -0.77 -0.08 -0.71 -0.20 -0.11
8732 || orf19.4678 || || || Predicted triglyceride lipase; Spider biofilm induced || 1 -0.06 -0.05 0.26 0.09 -0.03 -0.26 -0.21 -0.26 -0.38 -0.41 -0.39 -0.01 -0.18 -0.20 -0.20 -0.21
8733 || orf19.2191 || || || Ortholog(s) have role in endocytic recycling, peptidyl-diphthamide biosynthetic process from peptidyl-histidine and cytosol, endosome, nucleus localization || 1 -0.15 -0.11 -0.18 0.18 -0.01 -0.17 -0.27 -0.22 -0.56 -0.47 -0.31 -0.34 0.00 -0.28 -0.13 -0.39
8734 || orf19.3413 || FGR37 || || Protein lacking an ortholog in S. cerevisiae; transposon mutation affects filamentous growth || 1 -0.15 0.33 -0.35 1.20 -0.19 -0.81 -0.55 -0.38 -1.36 -1.74 -0.41 -0.77 0.03 -0.25 -0.62 -1.08
8735 || orf19.6834.10 || TAR1 || || Ortholog of S. cerevisiae Tar1p; Transcript Antisense to Ribosomal RNA; encoded within the 25S rRNA gene on the opposite strand; induced by Tbf1 || 1 -0.84 -0.90 -0.13 1.74 -1.31 -0.25 -0.44 -0.91 -3.64 -4.16 -1.41 -0.80 -0.93 -3.91 -0.36 -2.35
8736 || orf19.3419 || MAE1 || || Malic enzyme, mitochondrial; transcription regulated by Mig1, Tup1; colony morphology-related gene regulation by Ssn6; Hap43-repressed; Spider biofilm repressed || 1 -0.43 -0.31 0.45 0.61 -0.52 -0.22 -0.50 0.02 -0.78 -1.39 -1.38 -1.24 -0.22 -0.67 -1.62 -1.14
8737 || orf19.5840 || || || Ortholog(s) have cytoplasm, mating projection tip localization || 1 0.34 0.21 0.14 0.04 -0.02 -0.31 -0.17 -0.11 -0.65 -0.97 -0.25 -0.69 -0.19 -0.50 -0.46 -0.38
8738 || orf19.3111 || PRA1 || || Cell surface protein that sequesters zinc from host tissue; enriched at hyphal tips; released extracellularly; binds to host complement regulators; mediates leukocyte adhesion and migration; immunogenic in mouse; produced at ambient pH || 1 -0.07 -0.13 0.45 -0.23 -0.15 -0.24 -0.18 -0.12 -0.30 -0.64 -0.83 -0.29 -0.36 -0.65 0.14 -0.34
8739 || orf19.3012 || ARO80 || || Zn(II)2Cys6 transcription factor; transcriptional activator of aromatic amino acid catabolism; regulator of aromatic alcohol biosynthesis via the Ehrlich pathway; mutant is viable || 1 -0.25 -0.17 0.37 0.24 -0.22 0.01 -0.16 -0.21 -0.21 -0.61 -0.42 -0.13 -0.21 -0.78 0.32 -0.21
8740 || orf19.5535 || || || Predicted membrane transporter, member of the anion:cation symporter (ACS) family, major facilitator superfamily (MFS) || 1 -0.45 -0.52 -0.30 -0.37 -0.12 0.30 -0.32 -0.34 -0.05 -0.63 -0.51 -0.60 -0.30 -0.75 -0.34 -0.31
8741 || orf19.1563 || ECM3 || || Ortholog(s) have endoplasmic reticulum localization || 1 -0.64 -0.60 -0.52 -0.38 -0.25 -0.09 -0.55 -0.82 0.22 -0.76 -0.71 -0.62 -0.12 -1.61 -0.65 -1.06
8742 || orf19.2518 || || || Ortholog(s) have ATPase activator activity, soluble NSF attachment protein activity || 1 -0.41 -0.52 -0.46 -0.58 -0.28 -0.35 -0.41 -0.41 -0.48 -0.42 -0.53 -0.24 -0.66 -0.99 -0.48 -0.85
8743 || orf19.6550 || || || Putative mitochondrial outer membrane protein; regulated by Sef1p-, Sfu1p-, and Hap43p || 1 -0.70 -0.82 -0.13 -0.33 -0.50 0.02 -0.94 -0.83 0.22 0.05 -0.64 -0.26 -1.67 -1.76 -0.60 -0.98
8744 || orf19.2479 || UGA4 || || Putative gamma-aminobutyric acid/polyamine permease; nitrogen catabolite repressed gene, induced in absence of preferred N sources; transcriptionally induced upon phagocytosis by macrophage; gene regulation by nitrogen source requires Gat1p || 1 -0.16 -0.71 -0.43 -0.12 -0.65 -0.35 -0.57 -0.73 0.16 0.04 -0.89 -0.31 -0.43 -1.92 -0.57 -0.77
8745 || orf19.3106 || MET16 || || Putative 3'-phosphoadenylsulfate reductase; sulfur amino acid metabolism; reports differ on regulation during biofilm formation; fungal-specific; possibly an essential gene, disruptants not obtained by UAU1 method; Hap43p-repressed gene || 1 -0.80 -0.98 -0.11 -0.23 -0.95 -0.29 -0.44 -0.22 -0.31 0.08 0.25 0.51 -0.52 -0.84 -0.23 -0.38
8746 || orf19.6096 || TRP1 || || Phosphoribosylanthranilate isomerase; tryptophan biosynthesis; expected unifunctional, unlike trifunctional enzyme of some other fungi; complements E. coli trpC, S. cerevisiae trp1 mutant; CCT1 and TRP1 overlap; Spider biofilm repressed || 1 -0.64 -0.95 0.17 -0.06 -0.56 -0.36 -0.45 -0.34 -0.27 -0.33 -0.03 0.19 -0.86 -0.56 -0.45 0.01
8747 || orf19.3076 || || || Ortholog(s) have role in vesicle-mediated transport and COPI-coated vesicle, integral to Golgi membrane localization || 1 -0.58 -0.73 -0.08 0.15 -1.05 -0.48 -0.47 -0.07 -0.15 -0.21 -0.00 -0.16 -1.30 -0.61 -0.49 -0.29
8748 || orf19.4880 || || || Protein of unknown function; flow model biofilm induced || 1 -1.26 -1.34 -0.16 -0.36 -1.86 -0.98 -0.74 -0.43 0.36 -0.13 -0.58 -0.10 -1.00 -1.21 -0.86 -0.90
8749 || orf19.5449 || || || Predicted integral membrane protein; Spider biofilm induced || 1 -0.84 -0.81 -0.16 0.09 -1.01 -0.65 -0.37 -0.17 -0.23 0.07 -0.28 0.08 -1.09 -0.29 0.29 -0.39
8750 || orf19.3795 || AGP3 || || Putative serine transporter; possible role in assimilation of sulfur; F-12/CO2 early biofilm induced || 1 -0.70 -0.55 -0.05 0.50 -0.82 -0.30 -0.41 -0.33 -0.43 0.07 -0.25 0.16 -1.11 -0.33 -0.03 0.23
8751 || orf19.4565 || BGL2 || || Cell wall 1,3-beta-glucosyltransferase; mutant has cell-wall and growth defects, but wild-type 1,3- or 1,6-beta-glucan content; antigenic; virulence role in mouse systemic infection; rat catheter biofilm induced || 1 -0.66 -0.67 -0.08 0.38 -0.68 -0.02 -0.60 -0.72 -0.58 -0.65 -0.53 -0.06 -0.81 -0.36 0.04 -0.08
8752 || orf19.1525 || || || Ortholog(s) have role in nuclear-transcribed mRNA catabolic process, nonsense-mediated decay and cytoplasm, nucleus localization || 1 -0.48 -0.60 -0.14 0.33 -0.55 -0.02 -0.33 -0.34 -0.50 -0.10 -0.34 0.10 -0.35 -0.36 -0.19 -0.11
8753 || orf19.640 || || || Integral membrane protein of the ER; role in the synthesis of beta-1,6-glucan in the cell wall; S. cerevisiae ortholog required for cell viability; Spider biofilm induced || 1 -0.86 -0.72 0.37 0.52 -1.04 -0.66 -0.63 -0.38 -0.85 -0.37 -0.38 -0.27 -0.96 -0.52 -0.58 -0.17
8754 || orf19.1123 || || || Dubious open reading frame || 1 -0.87 -0.61 0.49 0.80 -0.35 -0.32 -0.50 -0.62 -0.69 -0.42 -0.46 -0.30 -0.99 -0.82 -0.74 -0.23
8755 || orf19.5345 || || || Putative ubiquitin-like polyubiquitin-binding protein; induced by nitric oxide independent of Yhb1; Spider biofilm repressed || 1 0.12 -0.07 0.04 0.21 -0.30 -0.51 -0.30 -0.04 -0.26 -0.15 -0.14 -0.35 -0.57 -0.60 -0.11 -0.49
8756 || orf19.5449 || || || Predicted integral membrane protein; Spider biofilm induced || 1 -0.39 -0.48 -0.16 0.24 -0.44 -0.72 -0.29 -0.10 -0.28 -0.04 -0.25 -0.46 -0.65 -0.54 0.12 -0.45
8757 || orf19.216 || || || Protein with a metallo-dependent phosphatase domain; ketoconazole-induced; upregulation correlates with clinical development of fluconazole resistance || 1 -0.60 -0.52 -0.15 0.26 -0.53 -0.43 -0.51 -0.08 -0.33 0.09 -0.36 -0.64 -0.29 -0.56 -0.50 -0.79
8758 || orf19.7121 || || || Protein of unknown function; Spider biofilm repressed || 1 -0.21 -0.36 -0.32 -0.04 -0.52 -0.14 -0.65 -0.06 -0.41 0.24 -0.65 -0.23 -0.79 -0.58 -0.21 -0.43
8759 || orf19.292 || || || Ortholog of C. parapsilosis CDC317 : CPAR2_102390, C. dubliniensis CD36 : Cd36_82960, Candida tenuis NRRL Y-1498 : CANTEDRAFT_133198 and Lodderomyces elongisporus NRLL YB-4239 : LELG_02116 || 1 0.12 -0.26 0.14 -0.06 -0.25 -0.28 -0.20 -0.11 0.05 -0.30 -0.57 -0.23 -0.26 -0.16 -0.35 -0.37
8760 || orf19.5429 || || || Ortholog(s) have DNA replication origin binding, ubiquitin-protein ligase activity || 1 -0.70 -0.43 0.56 0.43 -0.28 0.05 -0.55 -0.41 -0.02 -0.81 -0.56 -0.49 -0.41 -0.36 -0.14 -1.02
8761 || orf19.1078 || HBR2 || || Putative alanine glyoxylate aminotransferase; regulated by Gcn4p and hemoglobin; stationary phase enriched protein || 1 -0.68 -0.80 0.17 0.42 -0.81 -0.23 -0.42 -0.30 -0.02 -0.45 -0.67 -0.41 -0.47 -0.14 -0.41 -0.94
8762 || orf19.855 || || || Ortholog of C. dubliniensis CD36 : Cd36_18340, Candida tenuis NRRL Y-1498 : CANTEDRAFT_124631, Debaryomyces hansenii CBS767 : DEHA2D04356g and Pichia stipitis Pignal : PICST_34839 || 1 -0.27 0.19 -0.46 -0.08 -0.61 -0.30 -0.85 -0.63 -0.16 -0.67 -0.65 -0.22 -0.10 -0.05 -0.97 -0.41
8763 || orf19.4789 || || || Has domain(s) with predicted metal ion binding activity || 1 -0.32 -0.09 0.07 -0.04 -0.29 -0.09 -0.54 -0.72 -0.01 -0.31 -0.61 -0.32 0.02 -0.26 -0.94 -0.20
8764 || orf19.829 || SCH9 || || Protein kinase; involved in growth control, cell size, resistance to rapamycin, cations, chlamydospore formation, filamentous growth under some conditions, and virulence; prevents hyphal growth in hypoxia at high CO2; Spider biofilm induced || 1 -0.53 -0.48 0.09 0.07 -0.98 -0.31 -0.43 -0.89 -0.44 -0.02 -0.65 -0.56 -0.28 0.06 -1.12 -0.25
8765 || orf19.1825 || || || Protein of unknown function; mutants are viable; filament induced; regulated by Nrg1, Rfg1, Tup1 || 1 -0.55 -0.68 0.19 -0.26 -0.59 -0.50 -0.27 -0.31 -0.22 0.01 -0.75 -0.37 -0.29 -0.15 -0.40 -0.89
8766 || orf19.284 || || || Ortholog of C. dubliniensis CD36 : Cd36_82890, Debaryomyces hansenii CBS767 : DEHA2G01034g, Pichia stipitis Pignal : PICST_32242 and Candida guilliermondii ATCC 6260 : PGUG_04638 || 1 -0.58 -0.46 0.52 -0.08 -0.19 -0.28 -0.25 -0.16 0.04 -0.25 -0.46 -0.31 -0.13 -0.15 -0.65 -0.32
8767 || orf19.2303 || FGR16 || || Protein lacking an ortholog in S. cerevisiae; transposon mutation affects filamentous growth; fluconazole-downregulated || 1 -0.56 -0.37 0.22 -0.31 -0.38 -0.58 -0.42 -0.25 0.26 0.06 -0.61 -0.81 -0.14 0.08 -0.45 -0.52
8768 || orf19.5236.1 || || || ORF Predicted by Annotation Working Group; merged with orf19.5236 in Assembly 21 || 1 -0.65 -0.78 -0.10 -0.38 -0.39 -0.46 -0.47 -0.23 0.32 -0.22 -0.82 -0.58 -0.61 -0.21 -0.92 -0.25
8769 || orf19.2503 || || || Ortholog of S. cerevisiae : YGL138C, C. glabrata CBS138 : CAGL0H08910g, C. dubliniensis CD36 : Cd36_80910, C. parapsilosis CDC317 : CPAR2_102230 and Candida tenuis NRRL Y-1498 : CANTEDRAFT_109984 || 1 -0.96 -1.29 -0.18 -0.05 -0.56 -0.60 -0.55 -0.37 0.31 -0.38 -1.17 -1.43 -0.36 -0.55 -1.57 -1.04
8770 || orf19.5710 || || || Nucleoporin component of central core of the nuclear pore complex; mRNA binds She3 || 1 -0.38 -0.37 0.08 -0.12 -0.14 0.05 -0.25 -0.38 0.23 -0.29 -0.45 -0.56 0.03 -0.13 -0.56 -0.37
8771 || orf19.7644 || || || Ortholog(s) have ubiquitin-protein ligase activity, role in anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process, protein ubiquitination and anaphase-promoting complex localization || 1 -0.26 -0.27 0.06 -0.08 -0.10 -0.00 -0.44 -0.25 0.21 -0.13 -0.62 -0.48 -0.18 0.09 -0.34 -0.22
8772 || orf19.1942 || SGE1 || || Putative multidrug resistance factor; induced in low iron; regulated by Sef1, Sfu1, and Hap43 || 1 -0.43 -0.44 0.03 -0.39 -0.24 -0.41 -0.52 -0.39 -0.31 -0.49 -1.15 -0.71 0.14 0.18 -0.52 -0.53
8773 || orf19.7451 || FUN31 || || Putative PAS kinase involved in cell wall damage response; similar to S. cerevisiae Psk1p, a putative serine/threonine protein kinase; induced by Mnl1 under weak acid stress; rat catheter and Spider biofilm induced || 1 -0.57 -0.57 -0.35 -0.07 -0.23 -0.30 -0.32 -0.56 -0.17 -0.32 -0.94 -0.43 -0.13 0.24 -0.63 -0.47
8774 || orf19.7490 || || || Predicted membrane transporter; fucose:proton symporter family member, MFS superfamily; flow model biofilm induced || 1 -0.55 -0.39 -0.03 0.08 -0.57 -0.69 -0.31 -0.50 0.17 -0.53 -0.76 -0.19 -0.09 -0.11 -0.50 -0.60
8775 || orf19.7010 || || || Ortholog(s) have cytosol, ubiquitin ligase complex localization || 1 -0.08 -0.01 -0.07 0.13 -0.70 -0.48 -0.30 -0.37 -0.06 0.07 -0.80 -0.32 -0.11 0.05 -0.31 -0.64
8776 || orf19.4602 || MDH1-1 || || Predicted malate dehydrogenase precursor; macrophage-induced transcript; protein present in exponential and stationary growth phase yeast cultures; Spider biofilm repressed || 1 -0.32 -0.35 -0.26 -0.04 -0.92 -0.56 -0.08 -0.18 0.12 -0.17 -0.99 -0.70 -0.65 0.26 -0.20 -0.40
8777 || orf19.4602 || MDH1-1 || || Predicted malate dehydrogenase precursor; macrophage-induced transcript; protein present in exponential and stationary growth phase yeast cultures; Spider biofilm repressed || 1 -0.45 -0.56 -0.43 -0.17 -0.93 -0.91 -0.22 -0.34 -0.12 -0.28 -0.85 -0.68 -0.48 0.13 -0.36 -0.35
8778 || orf19.7300 || || || Protein of unknown function; Spider biofilm induced || 1 -0.52 -0.77 -0.51 -0.21 -1.06 -0.91 -0.34 -0.62 -0.09 -0.54 -1.54 -1.25 -0.30 -0.20 -1.01 -0.60
8779 || orf19.7300 || || || Protein of unknown function; Spider biofilm induced || 1 -0.57 -0.72 -0.29 0.22 -1.11 -0.80 -0.25 -0.63 -0.07 -0.58 -1.48 -1.29 -0.25 0.29 -0.65 -0.54
8780 || orf19.3981 || MAL31 || || Putative high-affinity maltose transporter; transcript is upregulated in clinical isolates from HIV+ patients with oral candidiasis; alkaline induced; Spider biofilm induced || 1 -0.64 -0.96 0.00 -0.10 -1.21 -1.14 -0.74 -0.81 -0.03 -0.53 -1.32 -1.39 -0.23 1.05 -1.27 -1.12
8781 || orf19.2890 || || || Has domain(s) with predicted sugar:hydrogen symporter activity, role in carbohydrate transport and Golgi membrane, integral to membrane localization || 1 -0.28 -0.41 -0.22 -0.10 -0.77 -0.78 -0.46 -0.45 -0.06 -0.13 -0.94 -0.48 -0.44 0.22 -1.01 -0.52
8782 || orf19.7490 || || || Predicted membrane transporter; fucose:proton symporter family member, MFS superfamily; flow model biofilm induced || 1 -0.56 -0.50 -0.31 -0.26 -0.58 -1.14 -0.50 -0.71 0.10 -0.49 -1.25 -0.41 -0.28 0.39 -0.77 -0.56
8783 || orf19.3311 || IFD3 || || Putative aldo/keto reductase; Mig1-regulated || 1 -0.48 -0.50 0.01 0.16 -0.61 -0.74 -0.46 -0.59 -0.30 -0.41 -1.15 -0.81 -0.24 -0.01 -0.50 -0.85
8784 || orf19.5311 || || || Ortholog of C. dubliniensis CD36 : Cd36_43850, C. parapsilosis CDC317 : CPAR2_402060, Pichia stipitis Pignal : PICST_68242, Candida tropicalis MYA-3404 : CTRG_00303 and Candida albicans WO-1 : CAWG_03390 || 1 -0.30 -0.37 -0.05 0.28 -0.49 -0.80 -0.57 -0.28 -0.34 -0.52 -1.02 -0.79 -0.21 0.12 -0.44 -1.16
8785 || orf19.1587 || HGT20 || || Putative glucose transporter of the major facilitator superfamily; the C. albicans glucose transporter family comprises 20 members; 12 probable membrane-spanning segments; regulated by Nrg1 || 1 -0.34 -0.12 0.22 0.34 -1.37 -1.49 -0.49 -0.43 0.29 -0.44 -1.36 -1.54 -0.49 0.24 -0.98 -1.33
8786 || orf19.850 || || || Ortholog(s) have protein-N-terminal asparagine amidohydrolase activity, protein-N-terminal glutamine amidohydrolase activity and role in cellular protein modification process, protein catabolic process || 1 -0.03 -0.12 -0.08 0.23 -1.40 -0.91 -0.54 -0.79 -0.17 -0.03 -1.16 -1.13 -0.29 0.26 -0.30 -0.54
8787 || orf19.850 || || || Ortholog(s) have protein-N-terminal asparagine amidohydrolase activity, protein-N-terminal glutamine amidohydrolase activity and role in cellular protein modification process, protein catabolic process || 1 -0.10 -0.41 0.12 0.03 -1.03 -0.98 -0.23 -0.74 -0.69 -0.28 -1.21 -1.34 -0.33 -0.04 -0.49 -0.66
8788 || orf19.2350 || || || Protein similar to S. cerevisiae Yor378w; MFS family transporter; transposon mutation affects filamentous growth; null mutants are viable; fungal-specific (no human or murine homolog) || 1 -0.54 -0.67 0.33 0.02 -1.72 -1.12 -0.52 -0.71 -0.54 -0.29 -0.88 -1.06 -1.21 0.37 -1.29 -0.12
8789 || orf19.2304 || || || Protein similar to S. cerevisiae Gvp36p; transposon mutation affects filamentous growth || 1 -0.30 -0.43 0.03 -0.10 -0.74 -0.61 -0.22 -0.20 -0.14 -0.23 -0.68 -0.35 -0.53 -0.18 -0.41 -0.33
8790 || orf19.6778 || || || Aminophospholipid translocase (flippase); maintains membrane lipid asymmetry in post-Golgi secretory vesicles; contributes to clathrin-coated vesicle formation and endocytosis; flow model biofilm repressed || 1 -0.52 -0.57 0.02 0.14 -0.75 -0.86 -0.40 -0.28 0.04 -0.12 -0.56 -0.56 -0.61 -0.07 -0.81 -0.31
8791 || orf19.7579 || FGR34 || || Protein lacking an ortholog in S. cerevisiae; transposon mutation affects filamentous growth || 1 -0.58 -0.54 -0.03 0.01 -0.55 -0.54 -0.47 -0.18 -0.01 -0.24 -0.47 -0.48 -0.61 -0.05 -0.60 -0.26
8792 || orf19.2003 || HNM1 || || Putative choline/ethanolamine transporter; mutation confers hypersensitivity to toxic ergosterol analog; colony morphology-related gene regulation by Ssn6; clade-associated gene expression || 1 -0.56 -0.69 -0.17 0.29 -2.10 -2.20 -0.94 -0.61 -1.49 0.16 -1.12 -1.65 -0.78 0.17 -1.34 -1.08
8793 || orf19.1397 || || || Has domain(s) with predicted heme binding activity || 1 -0.32 -0.40 -0.31 0.06 -0.77 -0.68 -0.29 -0.68 -0.90 -0.20 -0.64 -0.49 -0.37 0.19 -0.34 -0.47
8794 || orf19.5112 || TKL1 || || Putative transketolase; localizes to surface of yeast cells, not hyphae; soluble protein in hyphae; transcript regulated by Nrg1, Mig1, and Tup1; antigenic in human or murine infection; possibly essential (by UAU1 method) || 1 -0.09 -0.15 0.41 0.41 -0.82 -0.56 -0.69 -0.76 -0.44 -0.61 -0.27 -0.29 -0.19 -0.27 -0.11 -0.50
8795 || orf19.203 || STB3 || || Putative SIN3-binding protein 3 homolog; caspofungin induced; macrophage/pseudohyphal-repressed; rat catheter biofilm induced || 1 -0.90 -0.58 0.04 0.60 -0.62 -0.70 -1.18 -1.25 -0.45 -1.07 -0.64 -0.58 -0.54 -0.75 -0.32 -0.32
8796 || orf19.6209 || || || Predicted membrane transporter; monocarboxylate porter (MCP) family, major facilitator superfamily (MFS); possibly essential, disruptants not obtained by UAU1 method; rat catheter and Spider biofilm induced || 1 -0.26 -0.45 -0.05 0.34 -0.35 -0.31 -0.64 -0.70 -0.72 -0.57 -0.47 0.04 -0.77 -0.83 -0.34 -0.02
8797 || orf19.1382 || YEA4 || || Putative uridine diphosphate-N-acetylglucosamine (UDP-GlcNAc) transporter; required for cell wall chitin synthesis; induced by alpha pheromone in SpiderM medium || 1 -0.27 -0.45 -0.07 0.19 -0.54 -0.54 -0.85 -0.81 -0.61 -0.57 -0.63 0.17 -0.44 -0.92 -0.54 -0.30
8798 || orf19.2301 || || || Ortholog(s) have role in proteasome regulatory particle assembly and cytosol, nucleus localization || 1 -0.28 -0.27 0.01 -0.01 -0.69 -0.36 -0.65 -0.56 -0.52 -0.68 -0.64 0.17 -0.55 -0.47 -0.41 -0.33
8799 || orf19.5258 || || || Protein of unknown function; induced by nitric oxide || 1 -0.31 -0.22 0.23 -0.18 -0.62 -0.44 -0.45 -0.44 -0.44 -0.30 -0.34 -0.10 -0.27 -0.62 -0.43 -0.31
8800 || orf19.6642 || || || Ortholog(s) have role in ER to Golgi vesicle-mediated transport, cellular response to nitrogen starvation, negative regulation of G0 to G1 transition || 1 -0.26 -0.21 0.26 0.48 -0.85 -0.61 -0.73 -0.62 -0.66 -0.25 -0.42 0.09 -0.28 -0.53 -0.51 -0.27
8801 || orf19.7128 || SYS1 || || Putative Golgi integral membrane protein; transcript regulated by Mig1 || 1 -0.17 -0.35 0.06 0.26 -0.94 -1.00 -0.85 -0.45 -0.61 -0.18 -0.43 -0.51 -0.48 -0.71 -0.09 -0.25
8802 || orf19.183 || HIS3 || || Imidazoleglycerol-phosphate dehydratase, enzyme of histidine biosynthesis; functionally complements S. cerevisiae his3-1 mutation; hyphal-induced expression; regulated by Gcn2p and Gcn4p; fungal-specific (no human or murine homolog) || 1 0.08 -0.03 -0.16 0.13 -0.70 -0.60 -0.68 -0.67 -0.34 -0.23 -0.36 -0.26 -0.16 -0.79 0.12 -0.37
8803 || orf19.2401 || || || Ortholog(s) have cysteine-type endopeptidase activity || 1 -0.31 -0.29 -0.54 -0.22 -1.23 -0.82 -1.16 -1.14 -0.77 -0.76 -0.79 -0.40 -0.35 -0.98 0.03 -0.51
8804 || orf19.1093 || FLO8 || || Transcription factor; required for hyphal formation and CO2 induced white-opaque switching; regulates hyphal gene expression; required for virulence in mouse systemic infection; binds Efg1p; binds Mss11p via LisH motif; has LUFS domain || 1 -0.46 -0.53 0.06 0.06 -0.58 -0.65 -0.51 -0.59 -0.44 -0.10 -0.62 -0.20 -0.14 -0.44 -0.19 -0.49
8805 || orf19.6838 || || || Putative protein of unknown function, transcript upregulated in clinical isolates from HIV+ patients with oral candidiasis; Spider biofilm induced || 1 -0.54 -0.39 0.56 1.00 -0.94 -1.06 -0.79 -0.69 -0.70 -0.25 -1.39 -0.92 -1.13 -1.06 -0.42 -1.12
8806 || orf19.3749 || IFC3 || || Oligopeptide transporter; transcript induced by macrophage phagocytosis, BSA or peptides; fluconazole-induced; induced by Rim101 at pH 8; virulence-group-correlated expression; Hap43-repressed; Spider biofilm induced || 1 -0.30 -0.12 0.66 1.00 -2.16 -1.57 -0.94 -1.66 -0.78 -0.70 -2.05 -0.86 -1.90 -1.57 0.35 -0.56
8807 || orf19.1477 || || || Protein of unknown function; possible ER protein; Hap43p-repressed; Spider biofilm induced || 1 -0.11 -0.31 0.25 0.12 -0.56 -0.53 -0.89 -0.91 -0.43 -1.02 -1.65 -0.82 -1.34 -1.04 0.17 -0.77
8808 || orf19.6068 || SVF1 || || Putative survival factor; stationary phase enriched protein; fluconazole-induced; regulated by Gcn4p; repressed in response to amino acid starvation (3-AT treatment); fungal-specific (no human or murine homolog) || 1 -0.26 0.05 0.28 0.54 -0.41 -0.16 -1.00 -1.11 0.17 -0.45 -1.08 -0.53 -0.12 -0.67 -0.45 -1.01
8809 || orf19.4818 || || || Protein of unknown function; Spider biofilm induced || 1 -0.53 -0.61 -0.02 0.39 -0.33 -0.47 -0.93 -1.36 -0.23 0.02 -2.34 -0.74 0.10 -0.17 -0.66 -1.34
8810 || orf19.4818 || || || Protein of unknown function; Spider biofilm induced || 1 -0.68 -0.72 -0.28 0.60 -0.49 -0.44 -0.69 -1.40 -0.53 -0.11 -2.07 -0.93 0.20 -1.24 -0.61 -1.49
8811 || orf19.2633 || HGT14 || || Putative MFS glucose transporter; 20 member C. albicans glucose transporter family; 12 probable membrane-spanning segments; expressed in rich medium with 2% glucose; rat catheter and flow model biofilm induced || 1 -1.20 -1.18 -0.04 0.46 -0.78 0.04 -1.31 -1.86 -0.68 0.03 -2.26 -1.58 0.22 -0.85 -1.16 -2.36
8812 || orf19.2320 || || || Putative serine/threonine-protein kinase; possibly an essential gene, disruptants not obtained by UAU1 method || 1 -0.75 -0.37 0.21 -0.09 -0.35 0.30 -0.79 -0.94 -0.32 0.01 -0.80 -0.95 -0.33 -0.72 -0.58 -1.03
8813 || orf19.5454 || DAL1 || || Putative allantoinase; transcript regulated by Nrg1 and Mig1; macrophage/pseudohyphal-repressed || 1 -0.65 -0.48 0.29 -0.03 -0.39 0.27 -0.98 -0.91 -0.43 -0.13 -1.24 -1.08 -0.32 -0.34 -0.90 -0.67
8814 || orf19.6458 || || || Ortholog of C. dubliniensis CD36 : Cd36_72260, C. parapsilosis CDC317 : CPAR2_702840, Candida tenuis NRRL Y-1498 : CANTEDRAFT_115664 and Debaryomyces hansenii CBS767 : DEHA2B05940g || 1 -1.30 -1.25 -0.93 -0.02 -0.59 -0.21 -1.46 -1.98 -0.92 -0.37 -1.99 -1.37 -0.20 -0.67 -1.24 -1.79
8815 || orf19.6458 || || || Ortholog of C. dubliniensis CD36 : Cd36_72260, C. parapsilosis CDC317 : CPAR2_702840, Candida tenuis NRRL Y-1498 : CANTEDRAFT_115664 and Debaryomyces hansenii CBS767 : DEHA2B05940g || 1 -1.34 -1.20 -0.25 0.14 -0.78 0.18 -1.35 -1.72 -0.65 -0.21 -1.54 -1.23 -0.19 -0.66 -1.08 -1.23
8816 || orf19.6458 || || || Ortholog of C. dubliniensis CD36 : Cd36_72260, C. parapsilosis CDC317 : CPAR2_702840, Candida tenuis NRRL Y-1498 : CANTEDRAFT_115664 and Debaryomyces hansenii CBS767 : DEHA2B05940g || 1 -1.30 -1.16 -0.73 -0.01 -0.69 -0.15 -1.41 -1.63 -0.18 -0.24 -1.86 -1.05 -0.38 -0.36 -1.63 -0.85
8817 || orf19.6458 || || || Ortholog of C. dubliniensis CD36 : Cd36_72260, C. parapsilosis CDC317 : CPAR2_702840, Candida tenuis NRRL Y-1498 : CANTEDRAFT_115664 and Debaryomyces hansenii CBS767 : DEHA2B05940g || 1 -1.18 -1.28 -0.28 0.26 -1.15 0.34 -1.35 -1.66 -0.55 -0.32 -1.68 -1.15 -0.30 -0.60 -1.25 -0.49
8818 || orf19.6458 || || || Ortholog of C. dubliniensis CD36 : Cd36_72260, C. parapsilosis CDC317 : CPAR2_702840, Candida tenuis NRRL Y-1498 : CANTEDRAFT_115664 and Debaryomyces hansenii CBS767 : DEHA2B05940g || 1 -1.19 -1.57 -0.19 0.20 -1.08 0.21 -1.41 -1.81 -0.75 -0.30 -1.63 -0.62 -0.47 -0.37 -0.90 -0.78
8819 || orf19.4511 || || || Ortholog of Candida albicans WO-1 : CAWG_04197 || 1 -0.41 -0.43 0.22 0.23 -0.45 -0.16 -0.70 -0.75 -0.44 -0.13 -0.68 -0.47 -0.50 -0.43 -0.05 -0.61
8820 || orf19.2425 || HGT18 || || Putative glucose transporter of the major facilitator superfamily; the C. albicans glucose transporter family comprises 20 members; 12 probable membrane-spanning segments; expressed in rich medium with 2% glucose || 1 -0.83 -0.94 0.03 -0.05 -0.34 -0.14 -1.43 -1.21 -0.43 -0.51 -1.67 -0.75 -0.44 -0.64 -0.16 -0.68
8821 || orf19.2425 || HGT18 || || Putative glucose transporter of the major facilitator superfamily; the C. albicans glucose transporter family comprises 20 members; 12 probable membrane-spanning segments; expressed in rich medium with 2% glucose || 1 -0.66 -0.64 0.29 0.28 -0.22 0.26 -1.14 -1.17 -0.27 -0.53 -1.28 -0.62 -0.32 -0.57 -0.03 -0.63
8822 || orf19.2425 || HGT18 || || Putative glucose transporter of the major facilitator superfamily; the C. albicans glucose transporter family comprises 20 members; 12 probable membrane-spanning segments; expressed in rich medium with 2% glucose || 1 -0.44 -0.71 0.34 0.14 -0.11 0.24 -1.18 -1.24 -0.36 -0.60 -1.18 -0.28 -0.21 -0.41 -0.10 -0.57
8823 || orf19.4655 || OPT6 || || Putative oligopeptide transporter; fungal-specific (no human or murine homolog); expression of OPT6, OPT7, or OPT8 does not suppress defect of mutant lacking Opt1p, Opt2p, and Opt3p; alleles are nonidentical || 1 -0.51 -0.62 0.26 0.14 -0.32 0.23 -0.53 -0.75 -0.09 -0.28 -0.82 -0.39 -0.12 -0.10 -0.25 -0.16
8824 || orf19.6907 || || || Ortholog(s) have DNA binding activity and cytoplasm, nuclear chromatin localization || 1 -0.37 -0.25 0.69 0.60 -0.37 0.18 -1.05 -1.15 -0.05 -0.41 -1.12 -0.51 -0.29 -0.52 -0.50 -0.41
8825 || orf19.3809 || BAS1 || || Putative Myb-like transcription factor; ortholog S. cerevisiae Bas1, a regulator of purine biosynthetic genes; mutant exhibits adenine auxotrophy and abnormal colony morphology || 1 -0.34 -0.41 0.66 0.22 -0.50 0.05 -1.02 -0.94 -0.08 -0.73 -0.93 -0.22 -0.12 -0.70 -0.42 -0.66
8826 || orf19.4173 || || || Ortholog(s) have role in peptidyl-diphthamide biosynthetic process from peptidyl-histidine and cytosol localization || 1 -0.74 -0.66 0.87 0.44 -0.46 -0.15 -0.90 -0.98 -0.28 -1.04 -1.09 -0.75 -0.45 -0.81 -0.46 -0.33
8827 || orf19.2181 || || || Ortholog of Spathaspora passalidarum NRRL Y-27907 : spas_CGOB_00067 and Candida albicans WO-1 : CAWG_05895 || 1 -0.93 -0.62 0.59 0.66 -0.61 -0.53 -1.48 -1.46 -0.08 -0.94 -1.36 -1.04 -0.47 -0.64 -0.80 -0.49
8828 || orf19.417 || MTM1 || || Ortholog(s) have metallochaperone activity, role in manganese ion transport and mitochondrion localization || 1 -0.36 -0.28 -0.03 -0.01 -0.34 -0.03 -0.75 -0.76 -0.13 -0.55 -0.61 -0.46 -0.39 -0.34 -0.33 -0.35
8829 || orf19.4917 || || || Ortholog of Candida albicans WO-1 : CAWG_00155 || 1 -0.39 -0.46 0.26 0.32 -0.52 -0.20 -1.27 -1.28 -0.96 -1.10 -1.36 -0.90 -0.95 -0.64 -0.85 -0.53
8830 || orf19.7148 || TPO2 || || Putative polyamine transport protein; fungal-specific (no human or murine homolog) || 1 -0.44 -0.32 0.34 0.41 -0.59 0.21 -0.90 -0.94 -0.41 -1.06 -1.01 -0.62 -0.37 -0.89 -0.95 -0.59
8831 || orf19.6522 || || || Putative allantoate permease; Gcn4-regulated; Spider biofilm induced || 1 -1.08 -0.90 0.24 0.53 -0.35 -0.05 -0.68 -0.81 -0.37 -0.77 -0.90 -0.45 -0.05 -0.71 -0.32 -0.49
8832 || orf19.4908 || || || Dubious open reading frame || 1 -0.53 -0.59 0.26 0.11 -0.65 -0.81 -0.40 -0.55 -0.43 -0.81 -0.83 -0.56 -0.32 -0.43 -0.24
8833 || orf19.1093 || FLO8 || || Transcription factor; required for hyphal formation and CO2 induced white-opaque switching; regulates hyphal gene expression; required for virulence in mouse systemic infection; binds Efg1p; binds Mss11p via LisH motif; has LUFS domain || 1 -0.35 -0.50 0.18 0.24 -0.64 -0.57 -0.44 -0.60 -0.33 -0.39 -0.69 -0.48 -0.11 -0.86 -0.25 -0.27
8834 || orf19.77.1 || || || Protein of unknown function; Hap43-repressed gene || 1 -0.17 -0.57 -0.08 0.00 -0.29 -0.71 -0.45 -0.45 -0.56 -0.46 -0.68 -0.56 -0.22 -1.09 -0.48 -0.73
8835 || orf19.1863 || || || Has domain(s) with predicted Rho guanyl-nucleotide exchange factor activity, role in regulation of Rho protein signal transduction and intracellular localization || 1 -0.49 -0.41 -0.58 0.14 -0.93 -0.99 -0.58 -0.95 -0.67 -0.72 -1.00 -0.86 -0.21 -0.89 -0.94 -0.66
8836 || orf19.1397 || || || Has domain(s) with predicted heme binding activity || 1 -0.52 -0.67 -0.37 0.04 -1.48 -0.93 -1.03 -1.40 -1.46 -0.69 -1.59 -1.22 -0.61 -0.63 -1.13 -1.28
8837 || orf19.7030 || SSR1 || || Beta-glucan associated ser/thr rich cell-wall protein with a role in cell wall structure; GPI anchor; similar mRNA abundance in yeast-form and germ tubes; detected at germ tube plasma membrane; repressed in cells treated with Congo Red || 1 -0.33 -0.48 0.10 0.15 -1.35 -0.55 -0.57 -0.82 -0.66 -0.72 -1.14 -0.88 -0.20 -0.60 -0.40 -0.35
8838 || orf19.3746 || IFC1 || || Oligopeptide transporter; induced upon phagocytosis by macrophage; macrophage/pseudohyphal-repressed after 16h; fluconazole-induced; virulence-group-correlated expression; Hap43-repressed || 1 -0.04 -0.35 0.25 0.39 -0.96 -0.45 -0.25 -0.56 -0.80 -0.57 -1.15 -0.76 -0.53 -0.41 -0.80 -0.75
8839 || orf19.3180 || || || Ortholog(s) have phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity, role in phosphatidylinositol dephosphorylation and endoplasmic reticulum localization || 1 -0.01 -0.06 0.01 -0.17 -0.44 -0.34 -0.31 -0.61 -0.34 -0.83 -0.94 -0.83 -0.32 -0.40 -0.27 -0.57
8840 || orf19.5020 || || || Protein of unknown function; Hap43-induced; Spider biofilm induced || 1 -0.38 -0.34 0.29 -0.17 -0.38 -0.06 -0.34 -0.44 -0.36 -0.50 -0.78 -0.63 0.01 -0.44 -0.19 -0.87
8841 || orf19.6777 || || || Ortholog of Candida albicans WO-1 : CAWG_03032 || 1 -0.56 -0.35 0.51 -0.06 -0.25 -0.48 -0.55 -0.70 -0.24 -0.70 -1.07 -0.72 -0.13 -0.81 -0.59 -1.29
8842 || orf19.2197 || || || Has domain(s) with predicted N,N-dimethylaniline monooxygenase activity, NADP binding, flavin adenine dinucleotide binding activity and role in oxidation-reduction process || 1 -0.23 -0.06 0.16 0.25 -0.24 -0.41 -0.54 -0.55 -0.24 -1.17 -0.93 -1.02 0.04 -0.91 -0.21 -1.12
8843 || orf19.4678 || || || Predicted triglyceride lipase; Spider biofilm induced || 1 -0.17 -0.25 0.11 -0.12 -0.32 -0.45 -0.88 -0.68 -0.47 -1.04 -0.80 -0.74 -0.22 -0.79 -0.30 -0.64
8844 || orf19.4742 || || || Putative SH3-domain-containing protein || 1 -0.62 -0.38 0.04 0.10 -0.38 -0.48 -0.87 -0.93 -0.52 -1.35 -0.97 -1.10 -0.15 -1.00 -0.52 -1.15
8845 || orf19.4801 || || || Ortholog(s) have tRNA dimethylallyltransferase activity, role in tRNA modification and cytosol, mitochondrion, nucleolus localization || 1 -0.38 -0.34 0.19 -0.15 -0.30 -0.45 -0.66 -0.56 -0.25 -0.92 -0.60 -0.98 -0.15 -0.80 -0.23 -0.64
8846 || orf19.2082 || SAP30 || || Aspartic-type endopeptidase; involved in degradation of alpha pheromone; functional equivalent of S. cerevisiae Bar1; a-cell specific; induced by alpha pheromone || 1 -0.65 -0.28 0.18 -0.25 -0.37 -0.58 -1.08 -0.92 -0.75 -1.06 -1.05 -1.59 -0.29 -0.98 -0.87 -1.53
8847 || orf19.5121 || OPT5 || || Oligopeptide transporter; fungal-specific (no human or murine homolog); induced by BSA, but not by tetrapeptide or pentapeptide || 1 -0.58 -0.27 -0.04 0.06 -0.43 -0.72 -0.46 -0.63 -0.76 -0.85 -0.80 -0.86 -0.30 -0.60 -0.43 -0.93
8848 || orf19.5249 || || || Ortholog(s) have role in ascospore formation, meiosis and cytosol, nucleus localization || 1 -0.59 -0.41 -0.26 -0.08 -0.60 -0.67 -0.66 -0.70 -0.50 -0.52 -0.91 -0.83 -0.28 -0.33 -0.54 -1.14
8849 || orf19.4908 || || || Dubious open reading frame || 1 -0.67 -0.52 -0.10 -0.38 -0.49 -0.55 -0.59 -0.65 -0.31 -0.55 -0.90 -0.75 -0.35 -0.54 -0.38 -0.95
8850 || orf19.4363 || SGD1 || || Predicted small ribosomal subunit biogenesis protein; repressed in core stress response; transcript increases in populations of cells exposed to fluconazole over multiple generations; Spider biofilm induced || 1 -0.70 -0.66 -0.03 -0.06 -0.57 -0.03 -0.70 -0.79 -0.57 -0.68 -0.98 -0.70 -0.49 -0.71 -0.24 -1.15
8851 || orf19.4908 || || || Dubious open reading frame || 1 -0.36 -0.59 0.09 -0.19 -0.55 -0.43 -0.66 -0.50 -0.26 -0.90 -0.97 -0.34 -0.27 -0.40 -0.39 -0.85
8852 || orf19.3237 || || || Ortholog(s) have cytosol, mitochondrion, nucleus localization || 1 -0.34 -0.25 0.12 0.04 -0.17 -0.21 -0.68 -0.61 -0.26 -0.66 -0.89 -0.31 -0.01 -0.33 -0.01 -0.85
8853 || orf19.2425 || HGT18 || || Putative glucose transporter of the major facilitator superfamily; the C. albicans glucose transporter family comprises 20 members; 12 probable membrane-spanning segments; expressed in rich medium with 2% glucose || 1 -0.55 -0.52 -0.07 -0.08 -0.05 0.06 -0.69 -0.84 -0.43 -0.71 -0.98 -0.61 0.02 -0.55 -0.09 -0.77
8854 || orf19.5804 || HYU1 || || Putative hydantoin utilization protein A; induced upon adherence to polystyrene; regulated by Gcn2p and Gcn4p || 1 -0.52 -0.21 0.00 -0.30 -0.31 -0.15 -0.72 -0.69 -0.01 -0.97 -0.87 -0.62 -0.14 -0.25 -0.36 -0.41
8855 || orf19.6113 || || || Protein of unknown function; transcript detected on high-resolution tiling arrays || 1 -0.42 -0.35 0.18 -0.19 -0.29 -0.35 -0.41 -0.38 0.03 -0.67 -0.37 -0.44 -0.16 -0.23 -0.21 -0.43
8856 || orf19.4055 || || || Protein similar to S. cerevisiae Ybr075wp; transposon mutation affects filamentous growth; clade-associated gene expression || 1 -0.43 -0.30 0.08 -0.16 -0.24 -0.32 -0.43 -0.31 0.02 -0.66 -0.26 -0.58 -0.10 -0.51 -0.50 -0.27
8857 || orf19.5256 || || || Protein of unknown function; Hap43-repressed gene; induced by alpha pheromone in SpiderM medium || 1 -0.45 -0.17 0.30 -0.28 -0.29 -0.16 -0.71 -0.72 -0.02 -0.56 -0.54 -0.70 -0.32 -0.64 -0.65 -0.57
8858 || orf19.4908 || || || Dubious open reading frame || 1 -0.34 -0.41 0.25 0.35 -0.73 -0.46 -0.51 -0.47 0.09 -0.62 -1.05 -0.74 -0.46 -0.77 -0.54 -1.27
8859 || orf19.4908 || || || Dubious open reading frame || 1 -0.41 -0.39 0.13 0.12 -0.35 -0.51 -0.35 -0.45 -0.09 -0.41 -0.82 -0.19 -0.26 -0.73 -0.30 -0.76
8860 || orf19.4370 || || || Protein of unknown function; induced by nitric oxide; oxidative stress-induced via Cap1; fungal-specific (no human or murine homolog) || 1 -0.34 -0.22 -0.26 0.29 -0.43 -0.58 -0.61 -0.69 -0.50 -0.93 -0.53 -0.25 -0.12 -0.62 -0.21 -1.16
8861 || orf19.2745 || UME7 || || Putative transcription factor with zinc cluster DNA-binding motif; similar to S. cerevisiae Ume6p, which is a transcription factor involved in the regulation of meiotic genes || 1 -0.05 -0.18 0.05 0.41 -0.34 -0.40 -0.35 -0.40 -0.42 -0.78 -0.83 -0.25 -0.15 -0.71 -0.15 -0.56
8862 || orf19.2517 || || || Predicted membrane transporter, member of the drug:proton antiporter (12 spanner) (DHA1) family, major facilitator superfamily (MFS) || 1 -0.32 0.02 0.02 0.31 -0.05 -0.46 -0.74 -0.54 -0.27 -0.95 -0.82 -0.20 -0.07 -0.73 -0.56 -0.67
8863 || orf19.6942 || ORC3 || || Protein similar to S. cerevisiae Orc3p, which is a component of the origin recognition complex involved in DNA replication; mutation confers hypersensitivity to toxic ergosterol analog; induced under hydroxyurea treatment || 1 -0.15 -0.15 -0.01 0.00 -0.15 -0.42 -0.46 -0.58 -0.14 -0.39 -0.62 -0.06 -0.09 -0.49 -0.23 -0.26
8864 || orf19.1248 || || || Putative RNA polymerase II subunit B44; heterozygous null mutant exhibits resistance to parnafungin in the C. albicans fitness test; Spider biofilm repressed || 1 -0.26 -0.02 0.18 0.08 -0.35 -0.19 -0.75 -0.74 -0.22 -0.04 -0.69 -0.32 -0.10 -0.30 -0.53 -0.08
8865 || orf19.2751 || || || Predicted membrane transporter; member of the monocarboxylate porter (MCP) family, major facilitator superfamily; Hap43-induced gene; alkaline upregulated by Rim101; possibly an essential gene, disruptants not obtained by UAU1 method || 1 -0.10 -0.12 0.13 0.52 -0.89 -0.32 -1.53 -1.03 -0.25 0.07 -1.21 -0.31 -0.77 -0.36 -0.86 -0.34
8866 || orf19.5278 || || || Protein of unknown function; Spider biofilm induced || 1 -0.77 -0.46 0.31 0.52 -1.01 -0.34 -1.72 -1.36 -0.87 -0.25 -1.62 0.07 -1.40 -0.86 -0.85 -0.41
8867 || orf19.3080 || || || Ortholog(s) have role in attachment of spindle microtubules to kinetochore, cellular response to nitrogen starvation, cohesin localization to chromatin and double-strand break repair, more || 1 -0.38 -0.34 0.28 0.13 0.04 -0.51 -1.00 -0.55 -0.66 0.09 -1.08 -0.51 -1.07 -0.76 -0.64 -0.63
8868 || orf19.5162 || BCK1 || || Ortholog of S. cerevisiae Bck1; MAP kinase kinase kinase of cell integrity pathway; mutant is hypersensitive to caspofungin || 1 -0.35 -0.09 0.21 0.16 0.13 -0.04 -0.84 -0.75 -0.39 -0.32 -0.86 -0.33 -0.77 -0.31 -0.38 -0.24
8869 || orf19.4392 || DEM1 || || Putative mitochondrial exonuclease; alpha-factor induced || 1 -0.45 -0.54 0.27 0.07 0.20 -0.19 -1.03 -0.70 -0.14 -0.02 -0.78 -0.41 -0.60 -0.39 -1.03 -0.14
8870 || orf19.3758 || || || Ortholog(s) have fungal-type vacuole membrane localization || 1 -0.44 -0.62 0.39 0.32 -0.23 -0.10 -0.83 -0.79 -0.36 -0.13 -0.66 -0.53 -0.99 0.15 -0.40 -0.30
8871 || orf19.351 || || || Ortholog of S. cerevisiae : YPR153W, C. glabrata CBS138 : CAGL0L08382g, C. dubliniensis CD36 : Cd36_83540, C. parapsilosis CDC317 : CPAR2_404520 and Candida tenuis NRRL Y-1498 : CANTEDRAFT_115795 || 1 -0.14 -0.34 0.30 0.31 -0.54 -0.17 -1.15 -1.02 -0.42 -0.16 -0.74 -0.94 0.09 -0.25 0.07
8872 || orf19.4450 || ZCF23 || || Predicted Zn(II)2Cys6 transcription factor; ortholog of S. cerevisiae Gsm1; flow model biofilm induced || 1 -0.22 -0.50 0.11 -0.06 -0.59 -0.20 -1.03 -0.34 0.01 -0.03 -0.89 -0.38 -0.82 -0.39 -0.31 -0.32
8873 || orf19.4090 || || || Predicted membrane transporter, member of the fucose:proton symporter (FHS) family, major facilitator superfamily (MFS) || 1 -0.39 -0.41 0.03 0.25 -0.52 -0.16 -0.31 -0.58 -0.02 -0.33 -1.12 -0.76 -0.37 -0.52 -0.17 -0.27
8874 || orf19.5958 || CDR2 || || Multidrug transporter, ATP-binding cassette (ABC) superfamily; transports phospholipids, in-to-out direction; overexpressed in azole-resistant isolates; repressed in young biofilms || 1 -0.46 -0.35 -0.30 -0.11 -0.50 0.01 -1.13 -1.55 -0.43 -0.47 -2.28 -1.36 -1.41 -0.58 -0.80 -0.60
8875 || orf19.4090 || || || Predicted membrane transporter, member of the fucose:proton symporter (FHS) family, major facilitator superfamily (MFS) || 1 -0.69 -0.41 -0.24 -0.06 -0.63 -0.36 -0.52 -0.75 -0.22 -0.54 -1.68 -0.55 -1.05 -0.26 -0.56 -0.31
8876 || orf19.4862 || || || Putative integral membrane protein; S. cerevisiae ortholog Tvp23 localizes to late Golgi vesicles; rat catheter biofilm induced || 1 -0.31 -0.31 0.06 0.19 -0.75 -0.25 -0.65 -0.61 -0.16 -0.58 -1.26 -0.73 -0.84 -0.15 -0.66 -0.68
8877 || orf19.707 || APG7 || || Ortholog(s) have APG12 activating enzyme activity, APG8 activating enzyme activity || 1 -0.59 -0.19 0.20 0.33 -0.69 -0.64 -0.91 -0.97 -0.33 -0.21 -1.43 -1.04 -0.22 -0.19 -0.37
8878 || orf19.707 || APG7 || || Ortholog(s) have APG12 activating enzyme activity, APG8 activating enzyme activity || 1 -0.26 -0.39 0.19 0.38 -1.00 -0.69 -1.03 -1.09 -0.68 -0.65 -1.57 -0.75 -1.14 -0.46 -0.37 -0.41
8879 || orf19.2878 || PGA15 || || Putative GPI-anchored protein || 1 -0.15 -0.47 0.53 0.35 -0.83 -0.23 -0.82 -1.11 -0.44 -0.07 -1.53 -0.50 -0.85 -0.41 -0.49 -0.45
8880 || orf19.3212 || MID1 || || Putative stretch-activated Ca2+ channel of the high affinity calcium uptake system; role in thigmotropism; decreased transcription is observed upon fluphenazine treatment or in an azole-resistant strain with CDR1 and CDR2 overexpression || 1 -0.26 -0.32 0.16 -0.09 -0.57 -0.57 -0.31 -0.60 0.16 -0.19 -0.67 -0.21 -0.47 -0.12 -0.44 -0.39
8881 || orf19.6376 || PTC5 || || Mitochondrial protein phosphatase of the Type 2C-related family (serine/threonine-specific), involved in drug response and cadmium tolerance || 1 -0.25 -0.29 0.21 0.17 -0.82 -0.44 -0.76 -0.81 0.16 0.09 -1.35 -0.45 -0.83 0.09 -0.83 -0.22
8882 || orf19.5588 || PGA60 || || Putative GPI-anchored adhesin-like protein; hyphal-induced expression || 1 -0.09 -0.44 -0.09 -0.02 -0.63 -0.72 -0.47 -0.62 0.18 -0.47 -1.39 -0.41 -1.04 0.23 -0.79 -0.25
8883 || orf19.6376 || PTC5 || || Mitochondrial protein phosphatase of the Type 2C-related family (serine/threonine-specific), involved in drug response and cadmium tolerance || 1 0.00 -0.05 -0.08 -0.06 -0.48 -0.55 -0.60 -0.71 -0.35 -0.28 -1.04 -0.65 -0.75 0.01 -0.45 -0.46
8884 || orf19.6376 || PTC5 || || Mitochondrial protein phosphatase of the Type 2C-related family (serine/threonine-specific), involved in drug response and cadmium tolerance || 1 0.15 0.13 -0.18 -0.12 -0.35 -0.61 -0.47 -0.70 -0.03 0.03 -1.19 -0.63 -0.66 -0.05 -0.64 -0.40
8885 || orf19.2809 || CTN3 || || Peroxisomal carnitine acetyl transferase; no obvious metabolic, hyphal, virulence defects in Ura+ strain; induced by macrophage engulfment, hyphal growth, starvation, nonfermentable carbon sources; rat catheter, Spider biofilm induced || 1 0.17 -0.29 -0.05 -0.07 -0.87 -0.94 -0.32 -1.00 0.13 0.19 -2.00 -1.28 -0.81 -0.17 -0.59 -0.78
8886 || orf19.1422 || FZO1 || || Mitochondrial biogenesis protein; rat catheter and Spider biofilm induced || 1 -0.28 -0.25 -0.45 -0.20 -0.37 -0.40 -0.16 -0.46 -0.33 -0.43 -0.39 -0.18 -0.75 -0.17 -0.50 0.10
8887 || orf19.3166 || || || Ortholog(s) have role in Golgi to endosome transport, cell morphogenesis, cleistothecium development, conidium formation and endoplasmic reticulum organization, more || 1 -0.35 -0.38 0.02 0.01 -0.31 -0.61 -0.62 -0.42 -0.25 -0.35 -0.36 -0.14 -0.96 -0.19 -0.72 0.31
8888 || orf19.7228 || || || Possible Golgi membrane protein; transcript positively regulated by Tbf1; mRNA binds She3 || 1 -0.53 -0.51 -0.10 -0.02 -0.58 -0.70 -0.53 -0.34 -0.42 -0.07 -0.31 -0.46 -0.87 -0.29 -0.74 0.02
8889 || orf19.7228 || || || Possible Golgi membrane protein; transcript positively regulated by Tbf1; mRNA binds She3 || 1 -0.40 -0.49 -0.09 -0.07 -0.67 -0.48 -0.49 -0.21 -0.37 -0.35 -0.34 -0.19 -0.87 -0.14 -0.52 0.14
8890 || orf19.4845 || TVP18 || || Putative integral membrane protein; fluconazole-induced || 1 -0.44 -0.64 -0.45 -0.37 -0.99 -0.79 -0.78 -0.31 -0.55 -0.20 -0.43 -0.24 -1.12 0.07 -0.87 0.02
8891 || orf19.5360 || RPC11 || || Putative RNA polymerase III subunit C11; repressed in core caspofungin response; Spider biofilm induced || 1 -0.43 -0.49 -0.62 -0.36 -0.81 -0.56 -0.51 -0.42 -1.07 -0.19 -0.76 -0.62 -0.83 -0.52 -0.85 -0.13
8892 || orf19.6061 || || || Ortholog(s) have role in N-acylethanolamine metabolic process, N-acylphosphatidylethanolamine metabolic process and integral to mitochondrial inner membrane localization || 1 -0.39 -0.36 -0.19 -0.58 -0.69 -0.09 -0.63 -0.69 -0.35 -0.22 -0.85 -0.25 -0.83 -0.01 -0.64 0.13
8893 || orf19.538 || GPI2 || || Subunit of the GPI-N-acetylglucosaminyl transferase (GPI-GnT) that catalyzes the first step in GPI anchor biosynthesis || 1 -0.15 -0.31 -0.29 -0.14 -0.21 -0.05 -0.56 -0.47 -0.20 -0.24 -0.40 -0.08 -0.39 0.01 -0.50 -0.05
8894 || orf19.7184 || || || Ortholog of C. dubliniensis CD36 : Cd36_73640, C. parapsilosis CDC317 : CPAR2_702340, Candida tenuis NRRL Y-1498 : CANTEDRAFT_112965 and Debaryomyces hansenii CBS767 : DEHA2G16566g || 1 -0.34 -0.71 -0.04 -0.04 -0.44 -0.17 -0.63 -0.60 -0.33 -0.41 -0.45 -0.49 -0.71 -0.18 -0.18 -0.37
8895 || orf19.6399 || ATS1 || || Protein required for modification of wobble nucleosides in tRNA; induced upon adherence to polystyrene; regulated by Sef1, Sfu1, and Hap43 || 1 -0.43 -0.65 -0.44 -0.38 -0.75 -0.20 -0.73 -0.42 -0.46 -0.42 -0.18 -0.27 -0.51 -0.17 -0.58 -0.08
8896 || orf19.4678 || || || Predicted triglyceride lipase; Spider biofilm induced || 1 -0.61 -0.72 -0.30 -0.28 -0.44 -0.54 -0.94 -0.67 -0.66 -0.48 -0.54 0.09 -0.64 -0.16 -0.40 -0.56
8897 || orf19.3775 || SSK2 || || MAP kinase kinase kinase (MAPKKK); regulates Hog1 activation and signaling; repressed by ciclopirox olamine || 1 -0.76 -0.88 -0.23 0.18 -0.30 -0.12 -0.67 -0.55 -0.51 -0.25 -0.38 -0.10 -0.45 -0.34 -0.27 -0.05
8898 || orf19.4785 || PTC1 || || Putative protein phosphatase of the Type 2C-related family (serine/threonine-specific), similar to S. cerevisiae Ptc1p; mutant shows virulence defect || 1 -0.88 -1.06 -0.15 -0.07 -0.68 -0.28 -0.84 -0.58 -0.22 -0.33 -0.68 -0.29 -0.68 -0.35 -0.54 0.11
8899 || orf19.5657 || SWI1 || || Protein involved in transcription regulation; ortholog of S. cerevisiae Swi1p, which is a subunit of the SWI/SNF chromatin remodeling complex; interacts with Snf2p; SWI/SNF complex is essential for hyphal growth and virulence || 1 -0.68 -0.74 -0.24 -0.21 -0.52 -0.53 -0.88 -0.79 -0.57 -0.49 -0.46 -0.29 -0.46 -0.42 -0.63 -0.11
8900 || orf19.2075 || DFG5 || || N-linked mannoprotein of cell wall and membrane; possible signal transducer; role in hyphal growth and HWP1 induction in alkaline pH; GPI modification predicted; dfg5 dcw1 double mutant is inviable; caspofungin-induced, fungal-specific || 1 -0.32 -0.32 0.01 0.01 -0.05 -0.34 -0.39 -0.34 -0.28 -0.33 -0.20 -0.13 -0.32 -0.26 -0.28 0.04
8901 || orf19.1341 || PRR2 || || Putative serine/threonine protein kinase; mutation confers resistance to 5-fluorocytosine (5-FC) || 1 -0.94 -1.09 -0.37 -0.39 -0.94 -0.62 -0.91 -0.92 -0.23 -0.64 -0.58 0.05 -1.16 -0.89 -0.84 0.07
8902 || orf19.3545 || || || Ortholog(s) have protein serine/threonine kinase activity, role in meiotic anaphase II, protein phosphorylation, septation initiation signaling cascade and cellular bud neck, cytoplasm, new mitotic spindle pole body, nucleus localization || 1 -0.51 -0.60 -0.26 -0.31 -0.39 -0.51 -0.56 -0.50 0.06 -0.36 -0.42 -0.10 -0.97 -0.38 -0.54 0.03
8903 || orf19.6802 || || || Ortholog(s) have palmitoyltransferase activity, role in protein palmitoylation, vacuole fusion, non-autophagic and Golgi apparatus, endoplasmic reticulum, fungal-type vacuole membrane localization || 1 -1.58 -1.54 -0.82 -0.46 -0.58 -1.00 -1.37 -1.19 -0.27 -0.36 -0.81 -0.62 -1.45 -0.48 -0.61 -0.18
8904 || orf19.3184 || || || Ortholog(s) have Golgi apparatus, fungal-type vacuole membrane localization || 1 -0.82 -0.88 -0.53 -0.36 -0.55 -0.74 -0.80 -0.61 -0.49 -0.29 -0.44 -0.01 -1.36 -0.38 -0.25 0.12
8905 || orf19.3546 || PEX2 || || Ortholog(s) have ubiquitin-protein ligase activity, role in fatty acid metabolic process, protein import into peroxisome matrix and peroxisomal membrane localization || 1 -1.08 -1.16 -0.52 -0.27 -0.76 -0.59 -0.82 -0.54 -0.42 -0.23 -0.20 0.17 -1.20 0.03 -0.13 -0.06
8906 || orf19.3565 || || || Ortholog of C. dubliniensis CD36 : Cd36_19830, C. parapsilosis CDC317 : CPAR2_206470, Candida tenuis NRRL Y-1498 : CANTEDRAFT_113899 and Debaryomyces hansenii CBS767 : DEHA2C05676g || 1 -0.65 -0.72 -0.50 -0.16 -0.76 -0.55 -0.79 -0.30 -0.11 -0.13 -0.31 -0.37 -0.75 -0.35 -0.38 -0.47
8907 || orf19.2124 || || || Predicted alcohol dehydrogenase; Spider biofilm induced || 1 -0.18 -0.32 -0.45 -0.73 -1.00 -1.02 -0.71 -0.91 -0.50 -0.63 -1.08 -0.80 -1.01 -0.56 -1.24 -0.57
8908 || orf19.2124 || || || Predicted alcohol dehydrogenase; Spider biofilm induced || 1 -0.24 -0.31 -0.30 -0.54 -1.10 -0.88 -0.67 -0.92 -0.50 -0.54 -0.95 -0.69 -1.12 -0.62 -1.22 -0.27
8909 || orf19.5323 || MDH1-3 || || Predicted malate dehydrogenase; farnesol regulated; protein present in exponential and stationary growth phase yeast; Hap43p-repressed gene || 1 -0.39 -0.34 -0.08 -0.18 -1.21 -0.95 -0.73 -0.46 -0.53 -0.76 -1.16 -0.65 -0.54 -0.53 -1.52 -0.08
8910 || orf19.6756 || || || Ortholog(s) have Rab GTPase binding activity and Golgi apparatus, endoplasmic reticulum localization || 1 -0.14 -0.22 0.12 0.28 -0.57 -0.39 -0.61 -0.48 -0.40 -0.17 -0.58 -0.25 -0.66 -0.23 -0.56 -0.06
8911 || orf19.4845 || TVP18 || || Putative integral membrane protein; fluconazole-induced || 1 -0.57 -0.50 -0.16 0.05 -1.17 -0.77 -1.08 -0.65 -0.56 -0.35 -0.57 -0.65 -1.02 -0.26 -1.34 -0.54
8912 || orf19.2751 || || || Predicted membrane transporter; member of the monocarboxylate porter (MCP) family, major facilitator superfamily; Hap43-induced gene; alkaline upregulated by Rim101; possibly an essential gene, disruptants not obtained by UAU1 method || 1 -0.31 -0.60 -0.06 0.10 -0.95 -0.79 -1.20 -0.83 -0.26 -0.33 -0.89 -0.28 -0.80 0.06 -0.78 -0.56
8913 || orf19.654 || || || Predicted protein only found in C. albicans and C. dubliniensis; highly induced during chlamydospore development || 1 -0.64 -0.61 -0.26 0.29 -0.52 -0.13 -0.85 -0.69 -0.25 -0.38 -0.90 -0.46 -0.95 -0.32 -0.71 -0.48
8914 || orf19.3238 || || || Ortholog of Candida albicans WO-1 : CAWG_01469 || 1 -0.57 -1.29 -0.19 0.04 -1.12 -0.51 -1.02 -1.05 -0.43 -0.50 -1.32 -0.65 -1.23 -0.84 -1.33 -1.52
8915 || orf19.1989 || DCW1 || || Protein with predicted GPI modification; dfg5 dcw1 double mutant is inviable; not required for wild-type hyphal growth; upregulated in cyr1 mutant (yeast or hyphal form); Hap43-induced || 1 -0.68 -0.77 0.22 0.03 -0.75 -0.50 -0.68 -0.37 -0.32 -0.38 -0.85 -0.64 -0.61 -0.26 -0.80 -0.66
8916 || orf19.3375 || || || Ortholog of C. dubliniensis CD36 : Cd36_43270 and Candida albicans WO-1 : CAWG_03460 || 1 -0.76 -0.53 0.02 0.11 -0.43 -0.25 -0.74 -0.63 -0.34 -0.09 -0.88 -0.33 -0.43 -0.32 -0.94 -0.57
8917 || orf19.5464 || || || Protein of unknown function || 1 -2.47 -2.56 -0.46 -0.76 -2.92 -0.96 -1.99 -2.29 -1.63 -0.79 -1.96 -0.90 -2.14 -0.76 -2.67 -1.13
8918 || orf19.6008.3 || || || Ortholog of C. dubliniensis CD36 : Cd36_00920, Debaryomyces hansenii CBS767 : DEHA2F20724g, Pichia stipitis Pignal : PICST_32745 and Candida albicans WO-1 : CAWG_01277 || 1 -0.80 -0.78 -0.18 -0.25 -0.91 -0.56 -0.38 -0.59 -0.29 -0.58 -0.77 -0.02 -0.49 -0.17 -0.57 -0.14
8919 || orf19.3238 || || || Ortholog of Candida albicans WO-1 : CAWG_01469 || 1 -1.01 -0.58 -0.07 -0.20 -0.77 -0.23 -0.94 -0.57 -0.06 -0.47 -0.68 0.10 -0.46 -0.86 -0.80 -0.42
8920 || orf19.5675 || || || Protein involved in proteolytic control of sumoylated substrates; interacts with SUMO; member of the SWI/SNF family of DNA-dependent ATPases; Spider biofilm induced || 1 -0.75 -0.72 -0.07 -0.16 -0.58 -0.15 -0.72 -0.67 -0.29 -0.45 -0.64 -0.06 -0.67 -0.81 -0.92 -0.10
8921 || orf19.3238 || || || Ortholog of Candida albicans WO-1 : CAWG_01469 || 1 -1.02 -0.96 -0.46 -0.67 -0.83 -0.23 -1.25 -0.89 -0.50 -0.73 -0.89 -0.52 -0.91 -1.14 -1.18 -0.82
8922 || orf19.5966 || || || Ortholog of Candida albicans WO-1 : CAWG_02810 || 1 -1.12 -0.95 -0.60 0.10 -0.73 -0.05 -1.04 -1.27 -0.84 -0.29 -1.00 -0.20 -0.91 -0.78 -0.97 -0.47
8923 || orf19.1422 || FZO1 || || Mitochondrial biogenesis protein; rat catheter and Spider biofilm induced || 1 -0.30 -0.61 -0.63 -0.38 -0.59 -0.60 -0.40 -0.32 -0.23 -0.29 -0.55 -0.39 -0.77 -0.35 -1.08 -0.34
8924 || orf19.7643 || || || Ortholog(s) have 4-hydroxybenzoate octaprenyltransferase activity, antioxidant activity and role in cellular response to cadmium ion, detoxification of cadmium ion, ubiquinone biosynthetic process || 1 -0.82 -0.92 -0.74 -0.70 -0.54 -0.39 -0.55 -0.38 -0.26 -0.45 -0.96 -0.73 -1.11 -0.41 -1.05 -0.72
8925 || orf19.1795 || PUF3 || || Ortholog os S. cerevisiae Puf3; mRNA-binding protein involved in RNA catabolism; mutant is viable || 1 -0.36 -0.56 -0.64 -0.89 -0.62 -0.60 -0.84 -0.68 -0.34 -0.02 -1.02 -0.53 -0.70 -0.42 -0.85 -0.72
8926 || orf19.5200 || SIT4 || || Serine/threonine protein phosphatase catalytic subunit; has a role in cell wall maintenance, hyphal growth, and virulence in a mouse systemic infection model || 1 -0.63 -0.73 -0.64 -0.60 -0.99 -0.67 -0.70 -0.50 -0.67 -0.49 -0.64 -0.59 -0.67 -0.33 -0.47 -0.83
8927 || orf19.1751 || SPT23 || || Protein involved in regulation of unsaturated fatty acid biosynthesis; controls the expression of the Ole1p delta-9-fatty acid desaturase || 1 -0.52 -0.55 -1.14 -0.33 -0.51 -0.49 -0.96 -0.72 -0.62 -0.38 -0.64 -0.63 -0.32 -0.27 -0.70 -0.48
8928 || orf19.5219 || IRA2 || || GTPase-activating protein; negatively regulates RAS by converting it from the GTP- to the GDP-bound inactive form; Spider biofilm induced; flow model biofilm repressed || 1 -0.47 -0.39 -0.76 -0.75 -0.47 -0.61 -0.86 -0.84 -0.38 -0.62 -0.57 -0.46 -0.82 -0.07 -0.43 -0.36
8929 || orf19.366 || || || Ortholog(s) have double-stranded DNA binding activity, role in DNA damage checkpoint, double-strand break repair, reciprocal meiotic recombination and checkpoint clamp complex localization || 1 -0.61 -0.52 -0.65 -0.49 -0.53 -0.46 -0.87 -0.66 -0.49 -0.51 -0.46 -0.57 -0.68 -0.09 -0.51 -0.14
8930 || orf19.6046 || APC1 || || Putative Anaphase-Promoting Complex/Cyclosome subunit; essential for growth; periodic mRNA expression, peak at cell-cycle S/G2 phase || 1 -0.31 -0.42 -0.55 -0.36 0.01 -0.34 -0.59 -0.46 -0.52 -0.38 -0.47 -0.29 -0.77 -0.07 -0.55 -0.23
8931 || orf19.5428 || || || Putative Golgi membrane protein with a predicted role in manganese homeostasis; Hap43p-repressed gene; clade-associated gene expression || 1 -0.56 -0.70 -0.32 -0.17 -0.53 -0.13 -0.69 -1.03 -0.60 -0.64 -1.36 -0.71 -1.00 -0.83 -0.70 -0.20
8932 || orf19.5428 || || || Putative Golgi membrane protein with a predicted role in manganese homeostasis; Hap43p-repressed gene; clade-associated gene expression || 1 -0.79 -0.94 -0.51 -0.59 -0.75 -0.76 -0.96 -1.25 -0.78 -0.77 -1.34 -1.20 -0.85 -0.85 -0.78 -0.57
8933 || orf19.487 || SPT14 || || Putative DNA-binding transcription factor; predicted role in regulation of biogenesis of the cell wall; upregulated in biofilm; protein newly produced during adaptation to the serum || 1 -0.37 -0.21 0.12 -0.22 -0.34 -0.29 -0.32 -0.46 -0.38 -0.45 -0.51 -0.40 -0.31 -0.28 -0.26 -0.05
8934 || orf19.5764 || SKI8 || || Ortholog(s) have role in nuclear-transcribed mRNA catabolic process, 3'-5' exonucleolytic nonsense-mediated decay, nuclear-transcribed mRNA catabolic process, non-stop decay and protein complex assembly, more || 1 -0.42 -0.40 -0.32 -0.26 -0.61 -0.46 -0.98 -1.07 -0.45 -0.44 -0.72 -0.78 -0.31 -0.48 -0.27 -0.56
8935 || orf19.1479 || || || Ortholog of the mitochondria localized S. cerevisiae Pib2 protein of unknown function; has a FYVE zinc finger domain; Spider biofilm induced || 1 -0.58 -0.58 -0.73 -0.87 -0.82 -0.41 -1.01 -0.84 -0.32 -0.70 -1.06 -0.83 -0.50 -0.55 -0.41 -0.53
8936 || orf19.5867 || WSC1 || || Putative cell wall component; transcript upregulated in cyr1 mutant (yeast or hyphae); Spider and flow model biofilm induced || 1 -0.47 -0.64 -0.36 -0.42 -0.09 -0.33 -0.42 -0.76 -0.31 -0.47 -1.12 -0.72 -0.38 -0.69 -0.08 -0.58
8937 || orf19.155 || URE2 || || Functional homolog of S. cerevisiae Ure2p, which is a regulator of nitrogen utilization, and which also has an infectious prion form called [URE3]; forms [URE3] prion when expressed in S. cerevisiae || 1 -0.36 -0.43 -0.19 0.05 -0.76 -0.32 -0.65 -0.73 -0.48 -0.00 -0.77 -0.17 -0.66 -0.31 -0.34 -0.90
8938 || orf19.299 || ECM14 || || Ortholog(s) have endoplasmic reticulum, fungal-type vacuole localization || 1 -0.24 -0.22 -0.29 0.02 -0.47 -0.17 -0.55 -0.23 -0.24 -0.19 -0.41 0.03 -0.51 0.00 -0.28 -0.43
8939 || orf19.3872 || || || Protein of unknown function; oral infection induced; mutants have reduced capacity to damage oral epithelial cells; rat catheter biofilm repressed || 1 -0.82 -0.77 -0.23 0.01 -1.09 -0.56 -0.50 -0.28 -0.17 -0.14 -0.72 -0.07 -0.39 0.00 -1.43 -0.47
8940 || orf19.1283 || MEC1 || || Cell cycle checkpoint protein with a role in genome integrity; RNA abundance regulated by tyrosol and cell density || 1 -1.14 -0.91 -0.43 -0.24 -0.69 -0.31 -0.58 -0.26 -0.22 -0.09 -0.28 0.07 -0.22 -0.08 -0.97 -0.09
8941 || orf19.701 || CFL11 || || Protein similar to ferric reductase Fre10p; flucytosine repressed; possibly adherence-induced; possibly an essential gene, disruptants not obtained by UAU1 method; rat catheter biofilm repressed || 1 -0.82 -0.71 -0.26 -0.05 -0.82 -0.04 -0.49 -0.73 -0.33 -0.04 -0.36 0.23 -0.73 -0.34 -0.89 -0.30
8942 || orf19.5558 || RBF1 || || Transcription factor; glutamine-rich activation domain; binds RPG-box DNA sequences; predominantly nuclear; mutation causes accelerated induction of filamentous growth; antigenic during human oral infection; Sko1p-repressed || 1 -0.85 -0.73 -0.75 -0.74 -1.29 -0.56 -0.89 -0.62 -0.44 -0.38 -0.45 0.13 -0.60 -0.01 -1.22 0.41
8943 || orf19.6061 || || || Ortholog(s) have role in N-acylethanolamine metabolic process, N-acylphosphatidylethanolamine metabolic process and integral to mitochondrial inner membrane localization || 1 -0.23 -0.23 0.50 0.11 -0.69 -0.08 -0.52 -0.33 -0.01 -0.31 -0.88 -0.28 -0.83 -0.04 -0.61 0.20
8944 || orf19.4392 || DEM1 || || Putative mitochondrial exonuclease; alpha-factor induced || 1 -0.31 -0.18 0.40 0.09 -0.23 -0.19 -0.23 -0.35 -0.13 -0.25 -0.51 -0.14 -0.24 -0.24 -0.45
8945 || orf19.2252 || || || Protein of unknown function; rat catheter biofilm repressed || 1 -0.40 -0.19 0.85 0.41 -0.58 -0.29 -0.44 -0.46 -0.34 -0.40 -0.83 -0.36 -0.34 -0.03 -0.45 -0.07
8946 || orf19.6399 || ATS1 || || Protein required for modification of wobble nucleosides in tRNA; induced upon adherence to polystyrene; regulated by Sef1, Sfu1, and Hap43 || 1 0.00 -0.02 0.14 -0.10 -0.58 -0.08 -0.16 -0.20 -0.24 -0.29 -0.39 -0.29 0.01 0.15 -0.29 -0.00
8947 || orf19.7114 || CSA1 || || Surface antigen on elongating hyphae and buds; strain variation in repeat number; ciclopirox, filament induced, alkaline induced by Rim101; Efg1-, Cph1, Hap43-regulated; required for WT RPMI biofilm formation; Bcr1-induced in a/a biofilms || 1 -0.09 -0.12 0.28 0.23 -1.18 -0.04 -1.00 -1.28 -0.83 -1.17 -1.40 -0.47 -0.03 0.30 -0.77 -0.22
8948 || orf19.6720 || || || P-Loop domain-containing protein of unknown function; transposon mutation affects filamentous growth; Spider biofilm induced || 1 -0.84 -0.85 0.50 0.00 -1.04 -0.12 -0.71 -1.16 -0.51 -1.41 -1.48 -0.73 -0.55 0.47 -1.07 -1.22
8949 || orf19.6720 || || || P-Loop domain-containing protein of unknown function; transposon mutation affects filamentous growth; Spider biofilm induced || 1 -0.56 -0.73 0.63 0.30 -0.73 0.16 -0.85 -1.35 -0.36 -1.49 -1.58 -0.58 -0.56 0.30 -0.59 -0.92
8950 || orf19.6371 || || || Ortholog of C. dubliniensis CD36 : Cd36_33750, C. parapsilosis CDC317 : CPAR2_205650, Candida tenuis NRRL Y-1498 : cten_CGOB_00253 and Debaryomyces hansenii CBS767 : DEHA2A11088g || 1 -0.26 -0.25 0.38 0.05 -0.27 0.23 -0.21 -0.22 -0.06 -0.53 -0.48 -0.22 -0.15 0.17 -0.08 -0.07
8951 || orf19.6720 || || || P-Loop domain-containing protein of unknown function; transposon mutation affects filamentous growth; Spider biofilm induced || 1 -0.12 -0.25 0.87 0.49 -0.47 0.41 -0.57 -0.66 -0.17 -1.11 -0.94 -0.62 -0.41 0.45 -0.40 -0.08
8952 || orf19.6188 || || || Putative adhesin-like protein || 1 -0.78 -0.32 0.31 0.22 -0.47 0.35 -0.91 -0.81 0.02 -0.47 -0.91 -0.28 -0.49 0.44 -0.84 -0.18
8953 || orf19.366 || || || Ortholog(s) have double-stranded DNA binding activity, role in DNA damage checkpoint, double-strand break repair, reciprocal meiotic recombination and checkpoint clamp complex localization || 1 -0.38 -0.32 0.14 -0.09 -0.11 0.12 -0.34 -0.35 -0.12 -0.11 -0.44 -0.10 -0.22 0.36 -0.15 -0.07
8954 || orf19.6777 || || || Ortholog of Candida albicans WO-1 : CAWG_03032 || 1 -0.34 -0.41 0.44 0.22 -0.59 0.31 -0.61 -0.50 -0.82 -0.06 -0.88 -0.21 -0.65 0.07 -0.61 -0.65
8955 || orf19.149 || || || Protein of unknown function; transcript detected on high-resolution tiling arrays || 1 -0.30 -0.37 0.54 0.63 -0.50 0.44 -0.42 -0.44 -0.42 -0.42 -0.66 -0.06 -0.53 -0.03 -0.57 -0.89
8956 || orf19.2208 || || || Ortholog(s) have role in response to salt stress and cytoplasm localization || 1 -0.61 -0.62 0.31 0.06 -0.35 -0.26 -1.01 -0.82 -0.55 -0.14 -0.65 -0.16 -0.11 -0.15 -0.24 -0.53
8957 || orf19.2208 || || || Ortholog(s) have role in response to salt stress and cytoplasm localization || 1 -0.42 -0.53 -0.11 -0.22 -0.25 -0.09 -0.71 -0.62 -0.40 -0.08 -0.61 0.02 0.03 -0.01 0.01 -0.21
8958 || orf19.5501 || YAF9 || || Subunit of the NuA4 histone acetyltransferase complex; transcript regulated by Mig1; possibly an essential gene, disruptants not obtained by UAU1 method || 1 -0.71 -0.59 -0.55 0.10 -0.45 0.11 -0.92 -1.17 -0.80 -0.32 -0.59 -0.39 0.20 -0.25 -0.85 -0.35
8959 || orf19.1106 || || || Protein with Mob2p-dependent hyphal regulation; fluconazole-induced || 1 -0.58 -0.42 -0.49 0.22 0.35 -0.52 -1.22 -1.14 -0.53 -0.18 -0.79 -1.06 -0.04 -0.35 -0.70 -0.41
8960 || orf19.4227 || || || Ortholog of C. parapsilosis CDC317 : CPAR2_100400, C. dubliniensis CD36 : Cd36_52020, Debaryomyces hansenii CBS767 : DEHA2F14278g and Candida orthopsilosis Co 90-125 : CORT_0F00500 || 1 -0.27 -0.24 -0.10 0.19 -0.50 0.07 -0.69 -0.52 -0.36 -0.34 -0.38 -0.03 -0.28 -0.69 -0.80 -0.25
8961 || orf19.2394 || || || Ortholog(s) have cytoplasm, nucleus localization || 1 -0.49 -0.29 0.36 0.31 -0.48 0.18 -0.56 -0.59 -0.30 -0.60 -0.46 0.29 -0.22 -0.43 -0.95 -0.35
8962 || orf19.5675 || || || Protein involved in proteolytic control of sumoylated substrates; interacts with SUMO; member of the SWI/SNF family of DNA-dependent ATPases; Spider biofilm induced || 1 -0.44 -0.62 0.09 0.05 -0.28 0.18 -0.52 -0.59 -0.41 -0.61 -0.32 0.28 -0.49 -0.40 -1.16 0.25
8963 || orf19.7103 || || || Predicted exonuclease; Spider biofilm induced || 1 -1.08 -0.84 0.26 0.22 -0.64 0.31 -0.45 -0.86 -0.03 -0.48 -0.43 -0.11 -0.42 -0.16 -0.67 0.33
8964 || orf19.6923 || || || Ortholog(s) have chromatin binding activity, role in RNA polymerase II transcriptional preinitiation complex assembly and transcription factor TFIID complex localization || 1 -0.63 -0.64 0.18 0.07 -0.33 -0.26 -0.85 -0.54 0.11 -0.37 -0.44 0.00 -0.48 -0.03 -0.55 0.05
8965 || orf19.5346 || || || Ortholog(s) have role in transcription from RNA polymerase II promoter and transcription factor TFIID complex localization || 1 -0.63 -0.54 0.05 -0.42 -0.36 0.04 -0.69 -0.62 -0.14 -0.47 -0.49 -0.33 -0.10 -0.03 -0.59 -0.13
8966 || orf19.2074 || || || Ortholog of Candida albicans WO-1 : CAWG_03833 || 1 -0.27 -0.22 0.42 -0.14 -0.28 0.39 -0.58 -0.73 -0.20 -0.83 -1.01 -0.58 -0.00 -0.72 -0.68 -0.48
8967 || orf19.6629 || ISC1 || || Mitochondrial membrane localized inositol phosphosphingolipid phospholipase C; hydrolyzes complex sphingolipids to produce ceramide; mutant is viable || 1 -0.39 -0.35 0.49 0.25 -0.14 0.62 -0.50 -0.52 -0.01 -0.48 -0.71 -0.38 -0.07 -0.65 -0.32 -0.44
8968 || orf19.814 || SSY1 || || Amino acid sensor; required for wild-type hyphal growth on solid serum or Lees media, not under all conditions; 12 predicted membrane spanning regions; Hap43-repressed; Spider biofilm induced || 1 -0.28 -0.48 0.60 0.51 0.13 0.54 -0.49 -0.61 -0.27 -1.05 -1.02 -0.64 -0.24 -0.41 -0.38 -0.59
8969 || orf19.7331 || FCY24 || || Putative transporter; more similar to S. cerevisiae Tpn1, which is a vitamin B6 transporter, than to purine-cytosine permeases; transcription is regulated by Nrg1; Spider biofilm induced || 1 -0.76 -0.61 0.65 0.41 -0.02 0.26 -0.26 -0.38 -0.06 -0.73 -1.13 0.15 -0.48 -0.57 -0.66 -0.17
8970 || orf19.4637 || || || Ortholog(s) have role in SCF-dependent proteasomal ubiquitin-dependent protein catabolic process, cellular response to methylmercury and SCF ubiquitin ligase complex, cytosol localization || 1 -0.60 -0.38 0.58 0.25 -0.28 -0.06 -0.56 -0.74 0.01 -0.43 -0.65 0.28 -0.25 -0.21 -0.49 -0.03
8971 || orf19.2579 || || || Msh4 ortholog of S. cerevisiae; involved in meiotic recombination and is required for normal levels of crossing over; Spider biofilm induced || 1 -1.04 -0.91 0.63 -0.26 -0.38 0.26 -0.60 -1.01 0.25 -0.81 -1.12 0.09 -0.35 -0.28 -0.17 -0.23
8972 || orf19.1255 || ZCF5 || || Zn(II)2Cys6 transcription factor; colony morphology-related gene regulation by Ssn6 || 1 -0.66 -0.73 0.34 -0.29 0.17 0.28 -0.79 -0.89 -0.39 -0.23 -0.97 -0.04 -0.43 -0.74 -0.31 -0.43
8973 || orf19.5446 || || || Putative protein of unknown function; transcript is upregulated in clinical isolates from HIV+ patients with oral candidiasis; regulated by Ssn6 || 1 -1.06 -0.59 0.44 -0.11 -0.31 0.18 -1.08 -0.89 -0.31 -0.15 -1.17 -0.53 -0.41 -1.21 -0.71 -0.02
8974 || orf19.6187 || || || possible pseudouridine monophosphate glycosidase; overlaps orf19.6185 and orf19.618; has intron; Spider biofilm repressed || 1 -0.52 -0.48 0.38 0.18 -0.26 0.13 -0.49 -0.42 -0.06 -0.33 -0.21 -0.36 -0.43 -0.54 -0.27 -0.08
8975 || orf19.5475 || || || Sef1p-, Sfu1p-, and Hap43p-regulated gene || 1 -0.50 -0.62 0.69 0.64 -0.44 0.12 -0.66 -0.68 -0.18 -0.33 -0.84 -0.04 -0.75 -0.79 -0.19 -0.10
8976 || orf19.3184 || || || Ortholog(s) have Golgi apparatus, fungal-type vacuole membrane localization || 1 -0.02 -0.33 0.37 0.20 -0.09 -0.07 -0.56 -0.51 0.01 -0.47 -0.49 -0.14 -0.25 -0.75 -0.16 -0.08
8977 || orf19.3105 || || || Putative cytochrome P450 protein; possibly an essential gene, disruptants not obtained by UAU1 method || 1 -0.63 -0.80 0.58 0.42 0.27 1.05 -0.57 -0.58 -0.67 -0.44 -0.72 -0.19 -0.68 -1.06 -0.29 -0.11
8978 || orf19.2779 || || || Protein of unknown function; Hap43-repressed gene || 1 -0.90 -0.39 0.57 0.29 0.41 0.64 -0.36 -0.52 -0.05 -0.24 -0.67 -0.14 -0.69 -0.61 -0.42 -0.08
8979 || orf19.1885 || TAF4 || || Putative TFIID subunit; mutation confers hypersensitivity to toxic ergosterol analog || 1 -0.56 -0.45 0.54 0.46 -0.52 0.43 -1.05 -0.96 0.32 -0.17 -0.67 -0.20 -0.41 -0.17 -0.42 -0.13
8980 || orf19.6845 || || || Putative transcription factor with bZIP DNA-binding motif; rat catheter biofilm induced || 1 -0.23 -0.41 0.38 0.45 -0.04 0.24 -0.38 -0.59 -0.16 0.18 -0.91 -0.19 -0.33 -0.37 -0.27 -0.25
8981 || orf19.7406 || || || Ortholog of C. dubliniensis CD36 : Cd36_86220, C. parapsilosis CDC317 : CPAR2_404490, Candida tenuis NRRL Y-1498 : CANTEDRAFT_94473 and Debaryomyces hansenii CBS767 : DEHA2D01804g || 1 -0.38 -0.41 0.33 0.23 0.14 0.36 -0.38 -0.60 0.02 0.33 -0.56 -0.23 -0.65 -0.16 -0.37 -0.01
8982 || orf19.77.1 || || || Protein of unknown function; Hap43-repressed gene || 1 -0.26 -0.45 -0.27 -0.23 -0.96 0.11 -1.16 -0.88 -0.28 0.34 -1.66 0.16 -0.75 -0.25 -1.86 -0.61
8983 || orf19.1366 || || || Has domain(s) with predicted oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors activity || 1 -0.62 -0.36 0.17 0.09 -0.97 -0.57 -0.72 -0.67 -0.16 -0.52 -0.90 -0.99 -1.27 0.86 -0.16 -1.08
8984 || orf19.299 || ECM14 || || Ortholog(s) have endoplasmic reticulum, fungal-type vacuole localization || 1 -0.36 -0.09 -0.24 -0.29 -0.10 -0.34 -0.43 -0.17 -0.12 -0.11 -0.16 0.10 -0.36 0.10 -0.16 -0.41
8985 || orf19.3193 || FCR3 || || bZIP transcription factor; ortholog of S. cerevisiae Yap3; partially complements fluconazole sensitivity of S. cerevisiae pdr1 pdr3; Hap43-induced; required for yeast cell adherence to silicone substrate; flow model biofilm repressed || 1 -0.54 -0.57 -0.32 0.08 -0.71 0.05 -0.43 -0.35 -0.11 0.11 -0.45 -0.24 0.05 0.07 -0.34 -0.46
8986 || orf19.4735 || || || Ornithine cyclodeaminase family protein; Sef1, Sfu1, and Hap43-regulated; ortholog of S. cerevisiae YGL159W and S. pombe SPAP11E10.01; rat catheter biofilm induced || 1 -0.86 -0.87 -0.65 -0.19 -0.53 -0.45 -0.23 -0.35 0.10 0.16 -0.50 -0.03 -0.34 0.21 0.24 -0.81
8987 || orf19.6008.3 || || || Ortholog of C. dubliniensis CD36 : Cd36_00920, Debaryomyces hansenii CBS767 : DEHA2F20724g, Pichia stipitis Pignal : PICST_32745 and Candida albicans WO-1 : CAWG_01277 || 1 -0.91 -0.94 -0.54 -0.33 -0.54 -0.26 -0.00 -0.19 0.27 -0.13 -0.10 0.02 -0.59 0.32 -0.58 -1.04
8988 || orf19.2191 || || || Ortholog(s) have role in endocytic recycling, peptidyl-diphthamide biosynthetic process from peptidyl-histidine and cytosol, endosome, nucleus localization || 1 -0.56 -0.69 -0.50 -0.78 -0.34 0.24 -0.47 -0.13 -0.47 0.10 -0.21 -0.25 -0.77 0.46 -0.86 -0.37
8989 || orf19.5442 || || || Ortholog of C. dubliniensis CD36 : Cd36_80240, C. parapsilosis CDC317 : CPAR2_504040, Candida tenuis NRRL Y-1498 : CANTEDRAFT_130872 and Debaryomyces hansenii CBS767 : DEHA2C06006g || 1 -0.53 -0.54 0.05 -0.29 -0.21 -0.08 -0.62 -0.35 -0.14 0.37 -0.03 -0.01 -0.28 -0.10 -0.39 -0.24
8990 || orf19.4392 || DEM1 || || Putative mitochondrial exonuclease; alpha-factor induced || 1 -0.64 -0.79 -0.68 -0.23 0.31 -0.54 -1.17 -0.38 -0.41 0.15 -0.26 -0.52 -0.78 -0.09 -1.07 -0.29
8991 || orf19.5387 || VPS8 || || Putative vacuolar sorting protein; downregulated upon adherence to polystyrene || 1 -0.36 -0.24 -0.32 -0.39 0.06 -0.27 -0.49 -0.53 -0.19 -0.15 -0.22 0.14 -0.62 -0.24 -0.41 -0.02
8992 || orf19.5242 || CDC6 || || Putative ATP-binding protein with a predicted role in DNA replication; member of conserved Mcm1p regulon; periodic mRNA expression, peak at cell-cycle M/G1 phase || 1 -2.02 -1.84 -1.10 -0.94 0.15 -0.97 -1.69 -1.47 -0.77 0.51 -0.18 0.39 -1.77 -0.94 -1.08 -0.64
8993 || orf19.4683 || MLP1 || || Ortholog(s) have ribonucleoprotein complex binding activity || 1 -1.08 -0.96 -0.56 -0.41 0.11 -0.16 -0.80 -0.40 -0.29 -0.05 -0.09 -0.06 -0.86 -0.35 -0.22 -0.17
8994 || orf19.4733 || YMC2 || || Putative mitochondrial carrier protein; Gcn4-regulated; F-12/ CO2 early biofilm induced; Spider biofilm induced || 1 -0.80 -0.84 -0.40 0.15 -0.02 -0.06 -0.81 -0.46 -0.37 -0.24 -0.10 0.18 -1.00 -0.71 -0.52 -0.22
8995 || orf19.6185 || || || Putative pseudouridine-5'-phosphate glycosidase; overlaps orf19.6186 and orf19.6187; Spider biofilm repressed || 1 -0.68 -0.62 -0.28 -0.32 -0.19 -0.10 -0.52 -0.28 -0.12 -0.22 -0.01 -0.29 -0.61 -0.37 -0.41 -0.32
8996 || orf19.6656 || DUR3 || || Spermidine transporter; induced in strains from HIV patients with oral candidiasis; alkaline repressed; amphotericin B induced; colony morphology regulated by Ssn6; reduced oral epithelial cell damage by mutant; Spider biofilm induced || 1 -1.22 -1.30 -0.32 -0.44 -0.00 0.32 -0.69 -0.45 -0.30 -0.35 -0.68 -0.73 -1.42 -0.49 -1.24 -0.49
8997 || orf19.6656 || DUR3 || || Spermidine transporter; induced in strains from HIV patients with oral candidiasis; alkaline repressed; amphotericin B induced; colony morphology regulated by Ssn6; reduced oral epithelial cell damage by mutant; Spider biofilm induced || 1 -1.26 -1.39 -0.56 -0.40 0.03 0.41 -0.57 -0.40 -0.31 -0.42 -0.50 -0.05 -1.48 -0.07 -1.05 -0.20
8998 || orf19.4519 || SUV3 || || RNA helicase; mitochondrial RNA catabolism; required for chlamydospore formation, embedded hyphal growth, wild-type respiratory growth, alkaline-induced morphogenesis and SD or Spider biofilm formation; rat catheter biofilm induced || 1 -1.21 -1.53 -1.22 -1.65 -0.10 0.22 -0.58 -1.02 -0.71 0.00 -0.93 -0.15 -1.29 -0.44 -1.52 -0.94
8999 || orf19.6679 || || || Ortholog(s) have cytosol, nucleus localization || 1 -0.75 -0.68 -0.38 -0.55 -0.10 0.40 -0.33 -0.20 -0.21 0.14 -0.37 -0.26 -0.53 -0.57 -0.41 -0.71
9000 || orf19.1643 || || || Ortholog(s) have serine-type endopeptidase activity, role in regulation of mitochondrion organization, signal peptide processing and mitochondrial inner membrane localization || 1 -0.92 -1.05 -0.20 -0.32 -0.09 0.79 -1.00 -0.54 -0.10 0.32 -0.57 0.00 -1.14 -0.53 -0.38 -0.74
9001 || orf19.297 || DTD2 || || Ortholog(s) have D-leucyl-tRNA(Leu) deacylase activity, D-tyrosyl-tRNA(Tyr) deacylase activity, role in D-leucine catabolic process, D-tyrosine catabolic process, tRNA metabolic process and cytosol, nucleus localization || 1 -0.49 -0.29 -0.14 -0.12 -0.12 0.12 -0.22 -0.15 -0.06 0.22 -0.17 -0.11 -0.28 -0.30 -0.45 -0.08
9002 || orf19.473 || TPO4 || || Putative sperimidine transporter; fungal-specific (no human or murine homolog); Spider biofilm induced; promoter bound by Tec1 and Ndt80; Bcr1-repressed in RPMI a/a biofilms || 1 -1.20 -1.11 -0.49 -0.47 -0.85 -0.07 -0.14 -0.72 -0.26 0.07 -0.54 -0.66 -1.02 -0.71 -0.64 -0.32
9003 || orf19.473 || TPO4 || || Putative sperimidine transporter; fungal-specific (no human or murine homolog); Spider biofilm induced; promoter bound by Tec1 and Ndt80; Bcr1-repressed in RPMI a/a biofilms || 1 -0.98 -0.95 -0.57 -0.45 -0.62 0.02 -0.13 -0.60 -0.23 -0.09 -0.49 -0.64 -0.86 -0.80 -0.51 0.07
9004 || orf19.1237 || ARO9 || || Aromatic transaminase; Ehrlich fusel oil pathway of aromatic alcohol biosynthesis; Rim101-dependent pH-regulation (alkaline induced); Hap43-induced gene || 1 -0.69 -0.68 -0.60 -0.16 -1.01 0.44 -1.08 -1.34 -0.27 0.11 -1.83 -0.79 -0.82 0.41 -0.18 -0.12
9005 || orf19.5457 || || || Ortholog(s) have Golgi apparatus, endoplasmic reticulum localization || 1 -0.22 -0.26 -0.16 -0.10 -0.11 0.41 -0.76 -0.52 -0.04 0.11 -0.76 -0.14 -0.67 -0.01 0.07 -0.29
9006 || orf19.3009 || || || Ortholog of S. cerevisiae : YDR179W-A, C. glabrata CBS138 : CAGL0F05819g, C. dubliniensis CD36 : Cd36_02970, C. parapsilosis CDC317 : CPAR2_108540 and Candida tenuis NRRL Y-1498 : CANTEDRAFT_132957 || 1 -0.48 -0.57 -0.26 -0.56 -0.32 0.20 -0.14 -0.91 0.36 0.12 -0.99 -0.17 -0.23 -0.11 0.13 -0.42
9007 || orf19.2479 || UGA4 || || Putative gamma-aminobutyric acid/polyamine permease; nitrogen catabolite repressed gene, induced in absence of preferred N sources; transcriptionally induced upon phagocytosis by macrophage; gene regulation by nitrogen source requires Gat1p || 1 -0.54 -0.81 -0.74 -0.67 -0.67 -0.74 -0.76 -1.24 -0.25 0.24 -2.19 -0.52 -0.81 0.17 -0.51 -1.46
9008 || orf19.3208 || DAL52 || || Putative allantoate permease; mutant is viable; similar but not orthologous to S. cerevisiae Dal5 || 1 -0.82 -0.49 -0.18 -0.51 -0.52 -0.09 0.05 -0.46 0.44 0.12 -0.97 -0.18 -0.60 0.18 -0.68 -0.56
9009 || orf19.5585 || SAP5 || || Secreted aspartyl proteinase; sap4,5,6 triple null defective in utilization of protein as N source; virulence role effected by URA3; expressed during infection; mRNA localized to hyphal tip via She3; rat catheter and Spider biofilm induced || 1 -0.42 -0.40 -0.05 -0.70 -0.70 -0.75 -0.34 -0.51 0.69 -0.33 -0.88 -0.11 -0.30 0.02 -0.54 -0.64
9010 || orf19.1795 || PUF3 || || Ortholog os S. cerevisiae Puf3; mRNA-binding protein involved in RNA catabolism; mutant is viable || 1 0.06 -0.06 0.16 -0.24 -0.21 -0.08 -0.25 -0.26 0.05 0.10 -0.56 -0.17 -0.08 -0.11 -0.31 -0.39
9011 || orf19.3974 || PUT2 || || Putative delta-1-pyrroline-5-carboxylate dehydrogenase; alkaline upregulated; protein present in exponential and stationary growth phase yeast cultures; flow model biofilm induced; Spider biofilm induced || 1 -0.17 -0.13 -0.63 -0.40 0.08 -0.29 -0.55 -0.52 0.23 0.11 -1.20 -0.76 -0.80 0.08 -0.74 -0.69
9012 || orf19.3974 || PUT2 || || Putative delta-1-pyrroline-5-carboxylate dehydrogenase; alkaline upregulated; protein present in exponential and stationary growth phase yeast cultures; flow model biofilm induced; Spider biofilm induced || 1 -0.13 -0.02 -0.03 0.11 0.16 0.11 -0.57 -0.37 0.48 0.03 -1.17 -0.56 -0.82 0.18 -0.84 -0.36
9013 || orf19.7306 || || || Aldo-keto reductase; increased transcript associated with MDR1 overexpression, benomyl or long-term fluconazole treatment; overexpression does not affect drug or oxidative stress sensitivity; stationary phase enriched; flow biofim repressed || 1 -0.15 -0.04 -0.49 -0.06 0.46 1.02 -0.73 -1.07 -0.12 -0.23 -2.09 -0.92 -0.70 0.40 -0.88 -0.49
9014 || orf19.7068 || MAC1 || || Copper fist transcription factor; regulator of CTR1 copper transporter; induces CTR1 in low-copper conditions; ectopic expression causes copper-sensitive stimulation of filamentation in S. cerevisiae; Spider biofilm induced || 1 -0.36 -0.36 -0.19 -0.39 0.18 0.51 -0.44 -0.71 -0.40 -0.43 -1.27 -0.84 -0.47 -0.21 -0.50 -0.46
9015 || orf19.4507 || || || Protein of unknown function; Hap43-repressed; rat catheter biofilm repressed || 1 -0.41 -0.40 0.37 0.24 0.20 0.50 -0.44 -1.12 0.07 -0.73 -2.52 -1.39 -0.60 -0.37 -0.82 -0.81
9016 || orf19.6043 || || || Ortholog(s) have mitochondrial membrane localization || 1 -0.15 -0.31 -0.21 -0.08 0.03 -0.01 -0.17 -0.27 0.42 -0.12 -1.08 -0.60 -0.40 0.15 -0.23 -0.25
9017 || orf19.4682 || HGT17 || || Putative MFS family glucose transporter; 20 members in C. albicans; 12 probable membrane-spanning segments; induced at low (0.2%, compared to 2%) glucose in rich media; Spider biofilm induced || 1 -0.44 -0.75 -0.54 -0.46 0.54 0.23 -0.58 -0.65 0.50 0.14 -1.88 -0.78 -1.20 -0.49 0.14 -1.04
9018 || orf19.4682 || HGT17 || || Putative MFS family glucose transporter; 20 members in C. albicans; 12 probable membrane-spanning segments; induced at low (0.2%, compared to 2%) glucose in rich media; Spider biofilm induced || 1 -1.13 -1.15 -0.24 0.19 0.58 0.12 -1.36 -1.13 0.24 -0.07 -2.62 -0.94 -1.47 -0.38 -0.53 -0.61
9019 || orf19.554 || DIT2 || || Monooxygenase of the cytochrome P450 family; produces N,N'-bisformyl dityrosine from N-formyltyrosine; regulated by Nrg1, Mig1, and Tup1; role in chlamydospore formation; Spider biofilm induced || 1 -0.57 -0.60 -0.04 -0.45 0.51 0.18 -0.62 -0.30 0.21 -0.22 -1.25 -0.36 -0.67 0.37 -0.35 -0.38
9020 || orf19.918 || CDR11 || || Putative transporter of PDR subfamily of ABC family; Gcn4-regulated; induced by Rim101 at pH 8; Spider biofilm induced || 1 -0.68 -1.07 0.30 -0.16 -0.50 0.46 -0.20 -0.24 0.62 -0.16 -1.75 -0.96 -0.48 -0.00 -0.76 -0.52
9021 || orf19.918 || CDR11 || || Putative transporter of PDR subfamily of ABC family; Gcn4-regulated; induced by Rim101 at pH 8; Spider biofilm induced || 1 -0.71 -0.79 0.13 -0.18 -0.17 0.32 -0.26 -0.19 0.44 -0.45 -1.72 -0.77 -0.37 -0.15 -0.74 -0.70
9022 || orf19.918 || CDR11 || || Putative transporter of PDR subfamily of ABC family; Gcn4-regulated; induced by Rim101 at pH 8; Spider biofilm induced || 1 -1.11 -0.94 -0.19 -0.56 0.08 0.53 -0.07 -0.17 0.59 -0.34 -1.80 -0.94 -0.36 0.33 -0.37 -0.37
9023 || orf19.918 || CDR11 || || Putative transporter of PDR subfamily of ABC family; Gcn4-regulated; induced by Rim101 at pH 8; Spider biofilm induced || 1 -1.04 -1.07 -0.49 -0.79 -0.14 0.49 -0.14 -0.21 0.24 -0.45 -1.60 -1.09 -0.64 0.48 -0.31 -0.51
9024 || orf19.2270 || SMF12 || || Ortholog of S. cerevisiae Smf1; manganese transporter; Gcn4-regulated; Hap43, alkaline induced; caspofungin repressed; mutants are viable || 1 -0.81 -0.75 -0.17 -0.35 0.06 0.64 -0.40 -0.12 -0.06 -0.46 -0.95 -0.54 -0.47 0.28 -0.21 -0.62
9025 || orf19.2270 || SMF12 || || Ortholog of S. cerevisiae Smf1; manganese transporter; Gcn4-regulated; Hap43, alkaline induced; caspofungin repressed; mutants are viable || 1 -0.88 -0.84 -0.15 -0.31 -0.10 0.57 -0.50 -0.05 -0.08 -0.78 -0.93 -0.85 -0.40 0.11 -0.43 -0.68
9026 || orf19.431 || ZCF2 || || Zn(II)2Cys6 transcription factor; regulates sulfite tolerance through expression of SSU1 and CDG1; Hap43-repressed; Spider biofilm induced || 1 -1.11 -1.16 -0.93 -1.33 -0.70 0.41 -1.08 -1.29 -0.21 -1.76 -2.68 -2.19 -0.71 -0.81 -0.38 -1.64
9027 || orf19.431 || ZCF2 || || Zn(II)2Cys6 transcription factor; regulates sulfite tolerance through expression of SSU1 and CDG1; Hap43-repressed; Spider biofilm induced || 1 -1.03 -0.90 -0.52 -0.94 -0.25 0.53 -0.87 -0.91 0.16 -1.61 -2.44 -2.01 -0.49 -0.35 0.00 -1.54
9028 || orf19.431 || ZCF2 || || Zn(II)2Cys6 transcription factor; regulates sulfite tolerance through expression of SSU1 and CDG1; Hap43-repressed; Spider biofilm induced || 1 -0.69 -0.83 -0.56 -1.11 -0.04 0.66 -0.70 -0.92 0.25 -1.58 -2.43 -1.95 -0.30 -0.17 0.24 -1.35
9029 || orf19.431 || ZCF2 || || Zn(II)2Cys6 transcription factor; regulates sulfite tolerance through expression of SSU1 and CDG1; Hap43-repressed; Spider biofilm induced || 1 -0.60 -0.70 -0.43 -1.04 -0.13 0.61 -0.66 -0.92 0.17 -1.37 -2.33 -1.96 -0.48 -0.30 0.10 -1.13
9030 || orf19.3373 || || || Putative protein of unknown function; transcript upregulated in clinical isolates from HIV+ patients with oral candidiasis; Spider biofilm induced || 1 -1.38 -0.26 -0.28 -0.47 -0.00 -0.76 -0.46 -1.41 -1.57 -0.47 -0.33 0.43
9031 || orf19.2077 || ZCF9 || || Putative Zn(II)2Cys6 transcription factor; hypersensitive to toxic ergosterol analog ECC69 and/or ECC1384 || 1 -0.31 -0.24 -0.17 -0.43 0.15 0.05 -0.03 -0.66 0.11 -0.43 -0.99 -0.23 -0.41 -0.23 -0.23 -0.11
9032 || orf19.781 || DUR31 || || High affinity spermidine transporter; expression is induced by urea; fungal-specific (no human or murine homolog); not required for virulence in a mouse intravenous model || 1 -0.77 -0.83 -0.08 -0.31 -1.20 -0.23 0.08 -0.83 0.97 -0.25 -2.39 -0.80 -0.38 -0.53 -0.78 -0.50
9033 || orf19.781 || DUR31 || || High affinity spermidine transporter; expression is induced by urea; fungal-specific (no human or murine homolog); not required for virulence in a mouse intravenous model || 1 -0.80 -1.19 -0.08 -0.36 -1.37 -0.60 -0.42 -0.97 0.43 -0.19 -2.39 -1.34 -0.40 -0.88 -0.72 -0.98
9034 || orf19.2064 || || || Putative transcription factor with zinc finger DNA-binding motif || 1 -0.56 -0.57 -0.23 0.23 -0.37 -0.25 -0.08 -0.38 0.32 -1.04 -1.30 -0.87 -0.40 -0.34 -0.53 -0.40
9035 || orf19.2064 || || || Putative transcription factor with zinc finger DNA-binding motif || 1 -0.47 -0.74 0.03 0.41 -0.54 -0.08 -0.36 -0.46 0.23 -0.76 -1.34 -0.58 -0.51 -0.27 -0.37 -0.01
9036 || orf19.781 || DUR31 || || High affinity spermidine transporter; expression is induced by urea; fungal-specific (no human or murine homolog); not required for virulence in a mouse intravenous model || 1 -0.49 -0.60 0.43 0.50 0.07 -0.16 -0.26 -0.51 0.63 -0.45 -1.94 -0.82 -0.23 -1.09 -0.77 -0.47
9037 || orf19.5811 || MET1 || || Putative uroporphyrin-3 C-methyltransferase, methionine biosynthesis enzyme; upregulated by human whole blood or polymorphonuclear (PMN) cells; Hog1p-induced; fungal-specific (no human or murine homolog); Hap43p-repressed || 1 -0.14 -0.14 0.28 0.09 -0.22 0.80 0.09 0.23 1.07 -0.48 -1.38 -1.19 -0.13 -0.38 -0.10 -1.63
9038 || orf19.5842 || || || Protein with predicted siroheme synthase middle domains NAD(P)-binding; Hap43-repressed gene || 1 -0.14 -0.25 -0.32 -0.33 -0.29 -0.17 -0.25 0.37 0.37 -0.95 -1.49 -1.46 -0.29 -0.92 -0.56 -1.56
9039 || orf19.5842 || || || Protein with predicted siroheme synthase middle domains NAD(P)-binding; Hap43-repressed gene || 1 0.20 0.14 -0.53 -0.21 -0.26 0.62 0.47 0.54 0.81 -0.85 -2.66 -2.29 -0.28 -0.79 -0.78 -2.16
9040 || orf19.5811 || MET1 || || Putative uroporphyrin-3 C-methyltransferase, methionine biosynthesis enzyme; upregulated by human whole blood or polymorphonuclear (PMN) cells; Hog1p-induced; fungal-specific (no human or murine homolog); Hap43p-repressed || 1 -0.30 -0.31 -0.56 -0.35 -0.54 0.75 0.36 0.48 1.32 -0.36 -2.64 -1.86 -0.80 -0.80 -0.87 -1.82
9041 || orf19.4841 || SHY1 || || Cytochrome c oxidase biosynthesis protein; transcript regulated by Nrg1 and Mig1 || 1 -0.23 -0.37 0.06 -0.33 -0.08 0.44 -0.10 0.02 0.57 -0.64 -1.63 -0.92 -0.51 -0.21 -0.55 -1.31
9042 || orf19.4841 || SHY1 || || Cytochrome c oxidase biosynthesis protein; transcript regulated by Nrg1 and Mig1 || 1 -0.26 -0.22 -0.41 -0.59 -0.07 0.50 -0.05 -0.02 0.49 -0.54 -1.89 -0.84 -0.45 -0.22 -0.22 -0.91
9043 || orf19.1416 || COX11 || || Cytochrome oxidase assembly protein; transcript regulated by Nrg1; protein repressed during the mating process; Hap43-repressed gene; rat catheter biofilm induced || 1 -0.57 -0.68 -0.34 -0.77 -0.34 0.24 0.14 0.18 0.71 -0.39 -1.42 -0.56 -0.52 -0.42 -0.24 -0.50
9044 || orf19.1416 || COX11 || || Cytochrome oxidase assembly protein; transcript regulated by Nrg1; protein repressed during the mating process; Hap43-repressed gene; rat catheter biofilm induced || 1 -0.40 -0.39 -0.04 -0.49 -0.13 0.35 0.09 0.31 0.74 -0.29 -0.87 -0.46 -0.37 -0.04 0.20 -0.59
9045 || orf19.1159 || || || Protein similar to A. nidulans CysA serine O-trans-acetylase; suggests that C. albicans uses an O-acetyl-serine (OAS) pathway of sulfur assimilation; F-12/CO2 early biofilm induced; Spider biofilm induced || 1 -0.43 -0.43 -0.07 0.20 -0.07 1.09 -0.41 -0.25 0.27 -0.36 -1.48 -0.40 -1.10 -0.63 -0.23 -0.86
9046 || orf19.1159 || || || Protein similar to A. nidulans CysA serine O-trans-acetylase; suggests that C. albicans uses an O-acetyl-serine (OAS) pathway of sulfur assimilation; F-12/CO2 early biofilm induced; Spider biofilm induced || 1 -0.72 -0.79 -0.15 0.17 -0.09 0.81 -0.64 -0.55 -0.10 -0.65 -1.33 -0.19 -0.78 -0.87 -0.19 -0.83
9047 || orf19.4947 || || || Mitochondrial membrane protein of unknown function; Spider biofilm induced || 1 0.13 0.06 0.39 -0.83 -0.40 0.36 -0.72 -1.03 -0.05 -0.96 -1.77 -0.91 -1.59 -0.65 -0.60 -0.94
9048 || orf19.4720 || CTR2 || || Putative low-affinity copper transporter of the vacuolar membrane; induced by nitric oxide; clade-associated gene expression; rat catheter and flow model biofilm induced || 1 0.05 0.05 0.18 -0.21 -0.17 0.07 -0.23 -0.22 -0.06 -0.50 -0.34 -0.14 -0.10 -0.11 -0.12 -0.30
9049 || orf19.2474 || PRC3 || || Putative carboxypeptidase Y precursor; transcript regulated by Nrg1 and Mig1; regulated by Gcn2 and Gcn4 || 1 0.10 -0.10 0.30 -0.21 -0.26 0.21 0.27 -0.60 0.39 -0.58 -1.29 -0.40 0.06 -0.19 -0.28 -0.04
9050 || orf19.2474 || PRC3 || || Putative carboxypeptidase Y precursor; transcript regulated by Nrg1 and Mig1; regulated by Gcn2 and Gcn4 || 1 0.17 0.01 0.24 0.09 -0.41 0.39 0.27 -0.66 0.30 -0.60 -1.55 -0.22 -0.04 0.08 -0.05 -0.37
9051 || orf19.2474 || PRC3 || || Putative carboxypeptidase Y precursor; transcript regulated by Nrg1 and Mig1; regulated by Gcn2 and Gcn4 || 1 0.06 0.01 0.69 0.67 -0.48 0.40 0.20 -0.73 0.48 -0.57 -1.85 -0.54 -0.15 -0.21 -0.59 -0.44
9052 || orf19.7320 || LIP7 || || Probable lipase, part of a gene family whose members are differentially expressed during infection; lacks a signal sequence for secretion, unlike other family members; may have a role in nutrition or in creating an acidic microenvironment || 1 0.24 -0.19 0.19 0.44 -0.43 0.36 0.02 -0.82 0.70 -0.29 -1.98 -1.48 -0.54 0.40 -0.55 0.03
9053 || orf19.7320 || LIP7 || || Probable lipase, part of a gene family whose members are differentially expressed during infection; lacks a signal sequence for secretion, unlike other family members; may have a role in nutrition or in creating an acidic microenvironment || 1 -0.52 0.12 -0.12 0.29 -0.28 -0.65 0.14 -0.50 0.48 -0.10 -3.10 -0.65 -0.61 0.88 -1.11 -0.38
9054 || orf19.4509 || || || Protein of unknown function || 1 -0.08 0.05 -0.44 0.74 -0.15 -0.24 0.18 -0.71 0.81 -0.57 -1.66 -1.14 -0.23 -0.26 -1.72 -0.61
9055 || orf19.3279 || HYR4 || || Putative GPI-anchored adhesin-like protein; Rim101-repressed; constitutive expression independent of MTL or white-opaque status || 1 -0.05 -0.16 -0.26 -0.64 0.14 0.05 -0.41 -0.43 0.21 -0.83 -0.81 -0.64 -0.09 -0.18 -0.61 -0.18
9056 || orf19.2077 || ZCF9 || || Putative Zn(II)2Cys6 transcription factor; hypersensitive to toxic ergosterol analog ECC69 and/or ECC1384 || 1 -0.04 -0.39 -0.32 -0.13 0.25 0.63 -0.00 -0.30 -0.10 -0.51 -0.81 -0.38 -0.17 -0.42 -0.47 -0.41
9057 || orf19.1867 || || || Putative malate permease; induced during macrophage infection; regulated by Gcn2 and Gcn4; putative peroxisome targeting signal; Hap43-repressed; Spider biofilm induced || 1 -0.09 -0.27 -0.85 -1.20 0.40 1.33 -0.04 -0.80 0.61 -3.47 -2.39 -1.89 -1.97 -1.60 -2.45 -0.47
9058 || orf19.1867 || || || Putative malate permease; induced during macrophage infection; regulated by Gcn2 and Gcn4; putative peroxisome targeting signal; Hap43-repressed; Spider biofilm induced || 1 0.07 -0.08 -0.72 -0.14 0.43 1.39 -0.10 -0.50 1.12 -2.72 -2.05 -1.66 -1.41 -1.67 -2.04 -0.79
9059 || orf19.1867 || || || Putative malate permease; induced during macrophage infection; regulated by Gcn2 and Gcn4; putative peroxisome targeting signal; Hap43-repressed; Spider biofilm induced || 1 -0.09 -0.05 -0.47 -0.36 0.29 1.11 -0.04 -0.61 1.16 -2.16 -1.67 -1.52 -0.91 -1.51 -1.70 -0.32
9060 || orf19.1867 || || || Putative malate permease; induced during macrophage infection; regulated by Gcn2 and Gcn4; putative peroxisome targeting signal; Hap43-repressed; Spider biofilm induced || 1 0.26 0.29 0.07 -0.03 0.44 1.01 0.12 -0.21 0.76 -1.86 -1.34 -0.89 -1.08 -1.36 -0.88 -0.66
9061 || orf19.260 || SLD1 || || Sphingolipid delta-8 desaturase; catalyzes desaturation at C8 in the long-chain base moiety of ceramides in glucosylceramide synthesis, important for virulence; ketoconazole and hypoxia induced; Hap43-repressed; Spider biofilm induced || 1 0.08 -0.24 0.11 -0.30 0.16 0.82 -0.30 -0.28 0.80 -0.61 -0.74 0.09 -1.15 -0.98 -0.64 0.06
9062 || orf19.5362 || PSO2 || || Putative DNA cross-link repair protein; expressed in opaque or white MTLa/MTLa or MTLalpha/MTLalpha, but not MTLa/MTLalpha cells; telomere-proximal gene; mutation does not affect white-to-opaque phenotypic switching || 1 -0.22 -0.31 0.10 -0.23 0.25 0.52 -0.01 0.17 0.61 -0.36 -0.55 -0.09 -0.52 -0.22 -0.53 -0.22
9063 || orf19.4984 || || || Has domain(s) with predicted chitin binding, chitinase activity and role in carbohydrate metabolic process, cell wall macromolecule catabolic process, chitin catabolic process || 1 -0.10 0.05 0.03 -0.27 0.87 0.31 0.16 0.35 0.93 0.04 -0.01 -0.12 0.07 -0.43 -0.29 0.32
9064 || orf19.1802 || OFD1 || || Putative prolyl hydroxylase family member; regulates Ume6p stability in response to oxygen; inhibited by hypoxia; repressed by prostaglandins; Spider biofilm induced || 1 0.39 0.56 -0.15 -1.08 0.79 0.96 0.40 0.73 0.38 -0.44 0.61 0.19 -0.57 -0.47 -1.00 1.20
9065 || orf19.6103 || || || Ortholog(s) have role in ascospore wall assembly and cytosol localization || 1 0.06 0.21 -0.05 -0.27 -0.03 -0.06 0.32 0.16 0.16 -0.43 0.01 -0.12 -0.09 -0.05 -0.19 0.61
9066 || orf19.2064 || || || Putative transcription factor with zinc finger DNA-binding motif || 1 0.12 0.03 0.15 -0.05 -0.04 0.08 -0.03 -0.11 0.36 -0.33 -0.52 -0.48 0.05 -0.28 -0.18 0.48
9067 || orf19.1148 || || || Ortholog of C. dubliniensis CD36 : Cd36_11020 and Candida albicans WO-1 : CAWG_00266 || 1 0.23 0.12 0.32 0.51 -0.17 -0.10 0.03 -0.09 0.51 -0.65 -0.17 -0.71 -0.07 -0.45 -0.37 1.28
9068 || orf19.4170 || CSP2 || || Putative cell wall associated protein; C. albicans and C. dubliniensis specific gene highly induced during chlamydospore development in both species; localized to chlamydospore cell wall; Hap43-repressed; Spider biofilm induced || 1 0.25 0.40 1.00 0.71 -0.02 0.07 -0.51 -0.68 -0.01 -0.94 -0.52 -0.45 -0.41 -1.48 -0.90 1.27
9069 || orf19.4391 || || || Ortholog of C. dubliniensis CD36 : Cd36_28730, Candida tropicalis MYA-3404 : CTRG_00749 and Candida albicans WO-1 : CAWG_01683 || 1 0.43 0.49 0.07 0.33 0.35 0.68 -0.56 -0.33 0.18 -1.31 -0.76 0.89 -0.51 -2.74 -0.94 0.65
9070 || orf19.6142 || || || Ortholog(s) have double-stranded DNA binding activity, role in reciprocal meiotic recombination and condensed nuclear chromosome localization || 1 -0.69 -0.36 0.25 0.44 0.13 -0.05 -0.54 -0.73 0.13 -0.59 -0.75 -0.51 -0.28 -2.41 -0.59
9071 || orf19.2625 || || || Ortholog of Candida albicans WO-1 : CAWG_02051 || 1 -0.26 -0.27 -0.19 -0.34 -0.18 0.42 -0.69 -0.07 -0.54 -1.63 -0.59 0.82
9072 || orf19.1737 || || || Ortholog of Candida albicans WO-1 : CAWG_01802 || 1 -0.63 -0.29 0.14 -0.19 0.15 -0.33 -0.18 -0.11 0.24 -0.23 0.07 -0.32 0.12 -1.78 -0.58 0.52
9073 || orf19.4550 || || || Predicted MFS membrane transporter, member of the drug:proton antiporter (12 spanner) (DHA1) family; flow model biofilm induced || 1 -0.30 -0.07 0.12 -0.06 0.10 0.03 0.04 -0.15 0.62 -0.41 0.51 0.32 0.29 -0.97 -0.26 0.62
9074 || orf19.3442 || || || Putative oxidoreductase; Hap43-repressed gene || 1 -0.38 -0.25 -0.11 -0.50 0.41 0.74 0.27 0.01 0.33 -1.28 0.82 0.77 0.17 -0.37 -0.25 0.32
9075 || orf19.3280 || || || Ortholog of Candida albicans WO-1 : CAWG_01435 || 1 -0.85 -0.03 -0.87 -0.06 -0.37 0.13 -0.79 0.69 -3.31 1.24 -0.05 -0.91 -0.47
9076 || orf19.5620 || || || Stationary phase enriched protein; Gcn4-regulated; induced by amino acid starvation (3-AT), benomyl or in azole-resistant strain that overexpresses MDR1; flow model biofilm induced; rat catheter biofilm repressed; overlaps orf19.5621 || 1 -0.17 -0.16 0.27 -0.54 0.45 0.88 0.65 -0.37 0.30 -2.53 -0.11 0.16 -0.43 -0.42 -0.77 0.14
9077 || orf19.5620 || || || Stationary phase enriched protein; Gcn4-regulated; induced by amino acid starvation (3-AT), benomyl or in azole-resistant strain that overexpresses MDR1; flow model biofilm induced; rat catheter biofilm repressed; overlaps orf19.5621 || 1 -0.21 -0.32 0.40 -0.10 -0.15 0.73 0.47 -0.47 0.54 -2.88 -0.52 -0.09 -0.55 -0.92 -0.85 -0.02
9078 || orf19.5094 || BUL1 || || Protein similar but not orthologous to S. cerevisiae Bul1; a protein involved in selection of substrates for ubiquitination; mutants are viable; macrophage/pseudohyphal-induced; rat catheter biofilm induced || 1 -0.25 -0.21 -0.04 -0.09 -0.51 0.49 0.14 -0.51 0.20 -2.12 -0.80 0.23 0.12 -0.28 -1.22 0.29
9079 || orf19.5094 || BUL1 || || Protein similar but not orthologous to S. cerevisiae Bul1; a protein involved in selection of substrates for ubiquitination; mutants are viable; macrophage/pseudohyphal-induced; rat catheter biofilm induced || 1 -0.27 0.11 0.10 -0.03 -0.23 0.56 0.52 -0.21 0.60 -1.91 -0.51 0.25 0.25 -0.08 -1.19 0.21
9080 || orf19.2284 || || || Protein with an FMN-binding domain; Hap43-repressed; flow model biofilm induced || 1 0.22 0.15 0.38 0.16 -0.69 -0.64 0.64 -0.13 0.44 -1.40 -0.23 -0.20 -0.67 -0.42 -0.97 0.01
9081 || orf19.6995 || ATO6 || || Putative fungal-specific transmembrane protein || 1 -0.04 0.07 0.64 0.11 -0.44 -0.32 0.07 -0.26 0.68 -1.31 -0.41 0.03 0.05 -0.42 -1.01 0.28
9082 || orf19.4048 || DES1 || || Putative delta-4 sphingolipid desaturase; planktonic growth-induced gene || 1 0.55 0.34 0.53 -0.05 -0.65 -0.08 0.10 0.11 0.22 -0.81 -0.03 0.05 0.05 -0.28 -1.16 0.34
9083 || orf19.4094 || || || Ortholog of C. dubliniensis CD36 : Cd36_23450, C. parapsilosis CDC317 : CPAR2_407010, Candida tenuis NRRL Y-1498 : cten_CGOB_00249 and Debaryomyces hansenii CBS767 : DEHA2B01980g || 1 0.35 0.11 0.83 0.50 -0.29 0.93 0.08 -0.44 1.01 -1.20 -0.40 -0.02 -0.68 -0.62 -0.29
9084 || orf19.6889 || MKK2 || || Ortholog of S. cerevisiae Mkk2; MAP kinase kinase involved in signal transduction; macrophage-downregulated; mutants are viable and hypersensitive to caspofungin || 1 0.06 0.03 0.49 0.24 0.05 0.21 -0.16 -0.16 0.35 -0.20 -0.28 0.16 -0.14 -0.26 -0.21 -0.03
9085 || orf19.4287 || || || Putative oxidoreductase; Hap43-repressed gene; clade-associated gene expression || 1 0.05 -0.17 0.59 0.59 -0.35 0.44 0.33 -0.04 0.57 -0.49 -0.85 0.16 -0.27 -0.09 -0.29 0.42
9086 || orf19.1737 || || || Ortholog of Candida albicans WO-1 : CAWG_01802 || 1 -0.09 0.31 0.33 -0.50 -0.27 -0.55 0.12 -0.07 0.30 -0.21 -0.62 0.49 0.28 -0.66 -0.15 -0.05
9087 || orf19.6053 || CIS2 || || Putative role in regulation of biogenesis of the cell wall; upregulated in biofilm; Gcn4p-regulated || 1 -0.14 -0.02 0.55 0.01 -0.19 0.05 -0.39 -0.37 -0.27 -0.67 0.00 0.27 -0.17 -0.66 0.14 -0.75
9088 || orf19.3284 || || || Ortholog of Candida albicans WO-1 : CAWG_01431 || 1 -0.32 0.15 0.47 0.35 -0.30 0.13 0.19 -0.24 -0.47 -0.14 -0.07 -0.05 -0.40 0.62 -0.64
9089 || orf19.6687 || || || Protein of unknown function; rat catheter biofilm repressed || 1 -0.38 -0.34 0.83 -0.12 -0.97 0.81 0.47 -0.15 -0.73 0.08 0.10 0.47 -0.38 -0.55 0.79 0.13
9090 || orf19.3159.4 || || || Ortholog of Candida albicans WO-1 : CAWG_04594 || 1 -0.31 0.06 -0.03 0.03 0.24 0.17 0.76 -0.19 -0.32 -0.08 -0.46 -0.13 -0.35 0.43 -0.34
9091 || orf19.2745 || UME7 || || Putative transcription factor with zinc cluster DNA-binding motif; similar to S. cerevisiae Ume6p, which is a transcription factor involved in the regulation of meiotic genes || 1 -0.52 0.85 -0.19 -0.22 0.58 -0.35 -0.96 0.14 0.00 -0.54 0.56 0.03
9092 || orf19.937 || || || Ortholog of Candida albicans WO-1 : CAWG_04446 || 1 -0.07 0.74 -0.07 0.24 0.26 0.20 0.31 0.03 -0.30 -0.00 0.00 0.26 -0.28 0.36 0.32 0.13
9093 || orf19.440 || SDH1 || || Putative mitochondrial succinate dehydrogenase; macrophage/pseudohyphal-induced; repressed by nitric oxide || 1 -0.12 -0.14 0.29 -0.01 0.32 0.17 0.29 -0.02 0.22 0.06 -0.12 -0.12 -0.26 0.35 0.34 0.19
9094 || orf19.440 || SDH1 || || Putative mitochondrial succinate dehydrogenase; macrophage/pseudohyphal-induced; repressed by nitric oxide || 1 -0.35 -0.05 0.07 -0.02 0.41 0.06 0.37 0.15 0.31 0.07 -0.13 -0.24 -0.36 -0.23 0.12 0.05
9095 || orf19.4936 || || || Dubious open reading frame || 1 -0.26 -0.44 -0.07 -0.34 1.14 -0.29 0.16 -0.37 0.12 -0.06 -0.12 -0.93 -0.22 -0.05
9096 || orf19.6491 || || || Ortholog of Candida albicans WO-1 : CAWG_05572 || 1 -0.28 -0.51 -0.09 -0.16 1.43 0.06 0.14 -0.50 0.23 -0.25 -1.01 1.12
9097 || orf19.2783 || PIR32 || || Cell wall protein, putative structural component of the cell wall; mutation leads to increased chitin content, increased virulence and resistance to stresses; macrophage-induced gene || 1 0.35 -0.84 0.33 -0.32 0.94 0.68 -0.23 -0.10 -0.09 -0.05 -0.41 -0.72 0.28 -0.04
9098 || orf19.4448 || SOG2 || || Leucine-rich-repeat domain protein of RAM cell wall integrity signaling network; role in cell separation, azole sensitivity; required for hyphal growth; lacks orthologs in higher eukaryotes || 1 0.00 -0.14 0.10 -0.07 0.47 0.14 -0.19 -0.12 0.21 -0.04 -0.31 -0.05 -0.16 0.13 0.08 -0.18
9099 || orf19.7280 || || || Ortholog of Candida albicans WO-1 : CAWG_02163 || 1 -0.83 -0.51 0.35 0.70 1.30 1.03 -0.10 0.51 -0.11 -4.09 0.09 -0.24 0.20 0.80 -0.40
9100 || orf19.6267 || || || Ortholog of C. dubliniensis CD36 : Cd36_06020, C. parapsilosis CDC317 : CPAR2_803380, Candida tenuis NRRL Y-1498 : CANTEDRAFT_91858 and Pichia stipitis Pignal : PICST_30337 || 1 -0.25 -0.42 -0.14 -0.54 0.86 0.58 -0.38 0.15 -0.20 -1.74 0.73 -0.16 -0.53 0.70 0.07
9101 || orf19.6179 || || || Ortholog of Candida albicans WO-1 : CAWG_03090 || 1 0.53 0.29 -0.27 -0.39 0.71 -0.24 -0.48 0.29 -1.23 0.40 0.27 0.30 0.49
9102 || orf19.5353 || || || Ortholog of C. parapsilosis CDC317 : CPAR2_407790, C. dubliniensis CD36 : Cd36_24630, Candida orthopsilosis Co 90-125 : CORT_0C07130 and Spathaspora passalidarum NRRL Y-27907 : SPAPADRAFT_149801 || 1 0.48 0.19 -0.55 0.45 0.48 0.57 -0.18 -0.38 -0.05 -1.82 -0.16 0.13 -0.38 -0.00 0.38 0.78
9103 || orf19.3140 || || || Ortholog of Candida albicans WO-1 : CAWG_03159 || 1 0.58 -0.31 -0.75 0.87 -0.10 -0.05 0.03 0.18 -2.48 -0.07 -0.54 0.80 0.28
9104 || orf19.3373 || || || Putative protein of unknown function; transcript upregulated in clinical isolates from HIV+ patients with oral candidiasis; Spider biofilm induced || 1 -0.41 0.12 -1.44 0.30 0.38 0.39 0.15 0.29 -1.41 -0.44 1.24 -0.31 0.36 0.59
9105 || orf19.6179 || || || Ortholog of Candida albicans WO-1 : CAWG_03090 || 1 0.10 -0.23 -3.89 -0.42 1.35 0.12 -0.66 -0.01 -3.20 0.45 0.19 0.83 -0.27 1.28
9106 || orf19.609 || || || Protein of unknown function; white cell specific transcript || 1 0.02 -0.24 -0.93 0.87 0.72 0.23 0.20 0.08 -0.02 -0.74 0.23 0.07 -0.95 -0.04 -0.16
9107 || orf19.3903 || MRV3 || || Ortholog of Candida albicans WO-1 : CAWG_04793 || 1 -0.06 -0.41 -2.46 0.54 -0.02 -0.03 0.14 0.31 -0.62 -0.28 -0.63 0.68 -0.85 -1.23 -0.09 2.10
9108 || orf19.3876 || ZCF19 || || Predicted Zn(II)2Cys6 transcription factor || 1 -1.24 0.00 -1.62 -0.32 -0.42 -0.13 -0.16 -0.61 -0.13 -0.21 -0.23 -0.12 0.04 -1.01 0.57 0.52
9109 || orf19.3263 || ATO10 || || Putative fungal-specific transmembrane protein; rat catheter and Spider biofilm induced || 1 -0.52 -0.74 -4.72 -0.06 -0.01 -0.67 -0.22 0.36 -0.07 0.19 0.09 -0.16 -0.20 1.69
9110 || orf19.536 || || || Ortholog(s) have chromatin binding, protein complex scaffold, ubiquitin binding activity and role in histone acetylation, transcription from RNA polymerase II promoter || 1 -0.41 -0.46 -1.50 -0.57 -0.22 -0.65 -0.20 -0.12 -0.12 0.03 0.55 0.28 -0.04 -0.23 0.24
9111 || orf19.604 || || || Ortholog(s) have cytosol localization || 1 -0.36 -0.05 -0.99 0.28 0.78 -0.58 0.11 0.45 -0.28 0.52 0.22 -1.04 0.68 0.17
9112 || orf19.211 || || || Predicted homeodomain-like transcription factor; also has a metal-binding Ada DNA repair protein domain; Spider biofilm induced || 1 -0.09 -0.06 0.21 -0.13 0.35 0.46 -0.51 -0.38 -0.06 -0.25 0.29 -0.92 -0.58 -1.03 0.03 0.02
9113 || orf19.1737 || || || Ortholog of Candida albicans WO-1 : CAWG_01802 || 1 -0.97 -0.47 -0.00 -0.02 0.10 -0.28 -0.85 -0.82 -0.63 0.28 0.29 -0.16 -0.16 -0.12 -0.26 -0.36
9114 || orf19.7511 || || || Ortholog(s) have structural constituent of nuclear pore activity and role in cell division, nuclear pore organization, regulation of mitotic cell cycle || 1 -0.31 -0.12 -0.04 -0.23 0.15 -0.09 -0.31 -0.10 -0.17 0.07 -0.06 -0.15 -0.14 0.24 -0.20 -0.14
9115 || orf19.2915 || || || Ortholog(s) have ATPase activity, GTPase activity, adenosine-diphosphatase activity, cytidine diphosphatase activity, guanosine-diphosphatase activity, nucleoside-triphosphate diphosphatase activity, uridine-diphosphatase activity || 1 -0.22 -0.20 -0.47 -0.53 -0.17 -0.25 -0.17 -0.30 0.05 0.16 -0.40 -0.02 -0.45 0.32 -0.15 0.26
9116 || orf19.5589 || || || Protein of unknown function; transcript detected on high-resolution tiling arrays || 1 -0.22 0.12 -0.39 -0.19 0.06 -0.31 -0.15 0.14 -0.39 -0.03 -0.49 0.19 -0.48 0.44 -0.42 0.72
9117 || orf19.4472 || || || Ortholog of Candida albicans WO-1 : CAWG_00996 || 1 -0.08 -0.49 -0.59 -0.50 0.29 -0.54 -0.14 -0.55 -0.33 -0.16 0.12 0.36 -0.35 0.32 -0.44 0.50
9118 || orf19.6046 || APC1 || || Putative Anaphase-Promoting Complex/Cyclosome subunit; essential for growth; periodic mRNA expression, peak at cell-cycle S/G2 phase || 1 -0.29 -0.30 -0.44 -0.11 0.24 -0.19 -0.32 -0.19 -0.41 -0.10 -0.19 0.33 -0.66 0.17 -0.20 0.12
9119 || orf19.654 || || || Predicted protein only found in C. albicans and C. dubliniensis; highly induced during chlamydospore development || 1 -0.32 -0.13 -0.17 -0.04 0.34 -0.48 -0.38 -0.64 -0.48 -0.06 -0.11 -0.18 -0.62 -0.07 -0.40 0.50
9120 || orf19.1783 || YOR1 || || Protein similar to S. cerevisiae Yor1; ABC-type plasma membrane transporter involved in resistance to aureobasidin A; white cell type-specific transcript; Spider biofilm induced || 1 -0.56 -0.25 -0.82 0.09 0.35 0.25 -0.74 -0.43 -0.92 -0.03 -0.40 -0.04 -2.41 -0.97 0.32 -0.64
9121 || orf19.1783 || YOR1 || || Protein similar to S. cerevisiae Yor1; ABC-type plasma membrane transporter involved in resistance to aureobasidin A; white cell type-specific transcript; Spider biofilm induced || 1 -0.31 -0.20 0.20 0.24 0.57 0.50 -0.48 -0.05 -0.06 0.36 -0.08 0.14 -2.09 -0.37 0.38 -0.24
9122 || orf19.1581 || || || Planktonic growth-induced gene || 1 -0.55 -0.54 0.02 -1.33 0.33 0.37 -0.50 -0.04 -0.41 -0.35 0.13 0.37 -3.09 0.42 -0.41 -0.03
9123 || orf19.1272 || || || Protein of unknown function; may play a role in regulation of cell size; rat catheter biofilm repressed || 1 -0.15 -0.13 -0.13 -0.33 -0.06 0.04 -0.28 -0.12 0.18 -0.20 0.04 0.11 -0.87 -0.03 0.24 0.22
9124 || orf19.4442 || ALG9 || || Putative mannosyltransferase; similar to S. cerevisiae Alg9p; has HKEXRF motif || 1 0.18 -0.06 -0.06 -0.31 -0.14 -0.22 -0.55 -0.27 -0.20 -0.06 -0.01 0.00 -0.86 -0.14 -0.31 0.31
9125 || orf19.3991 || || || Ortholog(s) have role in cellular lipid metabolic process and cytosol localization || 1 0.21 0.25 -0.35 -0.29 -0.06 0.08 -0.40 -0.14 -0.77 0.21 0.28 0.00 -1.29 -0.44 -0.73 0.40
9126 || orf19.2360 || URA2 || || Putative bifunctional carbamoylphosphate synthetase-aspartate transcarbamylase; flucytosine induced; macrophage/pseudohyphal-induced; 5'-UTR intron; flow model biofilm repressed || 1 -0.34 -0.32 -0.58 -0.30 0.47 0.24 -0.40 -0.10 -0.57 0.14 0.21 0.24 -1.23 -0.11 -0.92 0.62
9127 || orf19.2360 || URA2 || || Putative bifunctional carbamoylphosphate synthetase-aspartate transcarbamylase; flucytosine induced; macrophage/pseudohyphal-induced; 5'-UTR intron; flow model biofilm repressed || 1 0.01 -0.01 -0.53 -0.40 0.54 -0.08 -0.08 0.47 -0.18 0.50 0.59 -0.25 -1.22 0.01 -0.97 0.17
9128 || orf19.7069 || || || Putative AdoMet-dependent proline methyltransferase; Hap43-induced; required for normal flow model biofilm growth; Spider biofilm repressed || 1 -0.07 -0.12 -0.51 -0.36 0.33 -0.11 -0.08 0.26 -0.59 0.43 0.59 -0.58 -0.99 -0.14 -0.56 -0.18
9129 || orf19.4779 || || || Putative transporter; slightly similar to the Sit1p siderophore transporter; Gcn4p-regulated; fungal-specific; induced by Mnl1p under weak acid stress || 1 -0.40 -0.01 -0.84 -0.13 0.30 0.25 -0.21 -0.18 -0.50 -0.22 0.52 -0.71 -0.72 0.10 -0.09 0.45
9130 || orf19.2397.3 || || || Putative aminotransferase; Hap43-repressed; homozygous Tn insertion decreases colony wrinkling in filament-inducing conditions, does not block true hypha formation in liquid media; rat catheter and Spider biofilm induced || 1 0.02 0.19 -0.65 -0.01 0.07 -0.25 -0.15 -0.80 -0.73 -0.67 -0.07 -0.34 -0.35 0.08 0.21 0.41
9131 || orf19.138 || FIG1 || || S. cerevisiae Fig1 ortholog; an integral membrane protein required for mating; role in thigmotropism; transcript is opaque-specific and a-specific; activated by Cph1 or alpha pheromone || 1 -0.34 -0.03 0.14 0.40 0.45 0.01 -0.29 -0.65 -0.43 0.02 -0.52 -0.36 -0.04 -0.38 -0.41 -0.03
9132 || orf19.6845 || || || Putative transcription factor with bZIP DNA-binding motif; rat catheter biofilm induced || 1 -0.08 -0.44 0.24 0.07 -0.05 0.15 -0.18 -0.77 -0.44 0.24 -0.58 -0.16 -0.15 -0.17 -0.14 -0.42
9133 || orf19.1992 || SIR2 || || Required for wild-type lifespan, asymmetric inheritance of oxidatively damaged proteins, rDNA silencing; regulates phenotypic switch in strain 3153A, not WO-1; partially complements S. cerevisiae sir2 mating defect; Spider biofilm induced || 1 0.19 -0.38 -0.10 0.54 0.19 0.91 -0.78 -1.32 -1.03 -0.11 -0.26 0.08 -0.21 -0.52 -0.93 -0.35
9134 || orf19.6845 || || || Putative transcription factor with bZIP DNA-binding motif; rat catheter biofilm induced || 1 0.16 -0.02 -0.26 -0.02 0.02 0.26 -0.51 -1.12 -0.63 -0.08 -0.81 -0.31 -0.06 -0.56 -0.61 -0.28
9135 || orf19.7208 || CSK1 || || Putative mitogen-activated protein (MAP) kinase with an unknown role; null mutant produces wrinkled colonies; similar to S. cerevisiae Smk1p, which is a protein kinase required for sporulation || 1 -0.25 -0.64 -0.49 0.23 -0.85 -2.20 0.02 0.80 -0.38 -0.63 -0.78 0.11
9136 || orf19.3660 || || || Ortholog of C. dubliniensis CD36 : Cd36_60600, C. parapsilosis CDC317 : CPAR2_602890, Candida tenuis NRRL Y-1498 : CANTEDRAFT_135512 and Debaryomyces hansenii CBS767 : DEHA2F15312g || 1 0.24 0.21 0.17 0.24 0.34 0.65 -0.29 -0.63 -0.27 -0.17 -0.23 0.50 0.16 -0.63 -0.17 0.37
9137 || orf19.7464 || || || Putative subtilisin-family protease; mutation confers hypersensitivity to toxic ergosterol analog || 1 -0.32 0.01 0.63 0.46 0.23 0.71 -0.38 -0.44 -0.61 -0.34 -0.21 0.07 0.22 -0.66 -0.87 0.35
9138 || orf19.4942 || || || Ortholog of Candida albicans WO-1 : CAWG_00134 || 1 0.03 0.10 0.32 -0.05 -0.58 0.86 -1.03 -0.91 -0.94 -0.52 -0.28 -0.37 -0.17 -0.27 -0.62 0.29
9139 || orf19.3738 || PGA22 || || Putative GPI-anchored protein; adhesin-like protein || 1 0.35 0.85 0.14 0.64 0.20 0.41 -1.12 -1.03 -1.28 0.04 -0.27 -0.19 -0.22 -1.04 -0.64 0.16
9140 || orf19.768 || SYG1 || || Ortholog(s) have role in signal transduction and Golgi apparatus, endoplasmic reticulum, mitochondrion, plasma membrane localization || 1 0.56 0.42 -0.33 -0.28 0.18 0.40 -0.56 -0.97 -1.22 -0.52 -0.20 0.02 -0.51 -0.72 -0.65 0.94
9141 || orf19.768 || SYG1 || || Ortholog(s) have role in signal transduction and Golgi apparatus, endoplasmic reticulum, mitochondrion, plasma membrane localization || 1 0.39 0.46 -0.20 -0.13 0.31 0.28 -0.43 -0.29 -0.89 -0.26 -0.18 -0.18 0.01 -0.90 -0.72 0.78
9142 || orf19.2879 || IFF5 || || Putative GPI-anchored protein; adhesin-like protein; possibly an essential gene, disruptants not obtained by UAU1 method || 1 0.04 0.14 0.11 0.14 0.26 0.57 -0.47 -0.34 -0.66 -0.37 -0.06 -0.35 0.07 -0.36 -0.34 0.91
9143 || orf19.4942 || || || Ortholog of Candida albicans WO-1 : CAWG_00134 || 1 -0.02 0.46 -0.09 -0.08 0.25 1.23 -0.22 -0.34 -1.97 -0.21 0.62 0.05 -0.05 -0.34 -0.43 0.47
9144 || orf19.4942 || || || Ortholog of Candida albicans WO-1 : CAWG_00134 || 1 -0.25 0.21 0.12 -0.16 0.20 0.93 -1.12 -1.20 -1.92 -0.56 0.51 0.18 -0.33 -0.74 -0.61 0.12
9145 || orf19.1335 || || || Ortholog of S. cerevisiae Mtr4, an ATP-dependent 3'-5' RNA helicase of the DEAD-box family; Hap43-induced gene; Spider biofilm induced || 1 -0.02 0.14 -0.20 -0.07 0.31 0.59 -0.93 -0.57 -1.51 0.12 -0.10 -0.16 -0.61 -0.43 -0.41 -0.06
9146 || orf19.2721 || || || Ortholog(s) have role in ascospore formation, regulation of mitotic cell cycle, regulation of translation and cytosol, nucleus localization || 1 0.24 0.06 0.18 -0.06 0.20 0.51 -0.20 -0.26 -0.70 -0.10 0.08 -0.12 -0.38 -0.15 -0.09 -0.26
9147 || orf19.2711.1 || MED20 || || Subunit of the RNA polymerase II mediator complex; involved in control of filamentous growth and Spider biofilm formation; rat catheter biofilm repressed || 1 -0.01 0.05 0.24 0.05 -0.28 0.18 -0.03 -0.12 -0.42 -0.25 0.12 -0.01 -0.36 0.11 -0.03 -0.01
9148 || orf19.2991 || HOL1 || || Putative MFS transporter; regulated by Nrg1; macrophage/pseudohyphal-repressed; induced by alpha pheromone in SpiderM medium; possibly an essential gene, disruptants not obtained by UAU1 method || 1 -0.40 0.05 0.43 -0.07 -0.61 0.87 -0.40 -0.57 -0.81 -0.31 -0.06 -0.43 -0.31 0.86 0.16 0.01
9149 || orf19.2995 || || || Protein of unknown function; induced by nitric oxide; rat catheter and Spider biofilm induced || 1 0.09 0.11 0.27 0.40 -0.41 0.36 -0.68 -0.43 -0.93 -0.27 -0.07 -0.20 -0.38 0.27 0.44 0.09
9150 || orf19.726 || PPZ1 || || Protein phosphatase Z; type 1 family serine/threonine specific protein phosphatase involved in cation homeostasis and cell wall integrity || 1 -0.05 -0.08 0.25 0.25 -0.27 0.35 -0.52 -0.41 -0.29 -0.17 -0.06 0.21 -0.47 0.28 0.69 0.07
9151 || orf19.646 || GLN1 || || Putative glutamate synthase; regulated by Tsa1, Tsa1B under H2O2 stress conditions; Spider biofilm induced || 1 -0.81 0.04 -0.20 0.06 -0.30 0.76 -0.22 -0.64 -0.48 -0.72 0.01 0.24 -0.28 0.06 0.63 0.77
9152 || orf19.1679 || || || Ortholog of C. dubliniensis CD36 : Cd36_81550, C. parapsilosis CDC317 : CPAR2_503570, Candida tenuis NRRL Y-1498 : cten_CGOB_00261 and Debaryomyces hansenii CBS767 : DEHA2D15378g || 1 -0.92 -0.38 -0.09 0.50 -0.32 0.66 -0.72 -0.96 -0.64 -0.09 0.29 0.05 -0.40 0.17 -0.14 0.83
9153 || orf19.5217 || TES1 || || Putative acyl-CoA thioesterase || 1 -0.20 -0.37 -0.23 0.15 -0.23 0.64 -0.66 -0.61 -0.57 -0.28 0.00 0.04 -0.48 -0.26 -0.12 0.22
9154 || orf19.6845 || || || Putative transcription factor with bZIP DNA-binding motif; rat catheter biofilm induced || 1 -0.64 -0.98 -0.07 0.27 -0.14 0.93 -0.50 -0.89 -0.04 0.44 -0.75 -0.08 -0.24 -0.06 -0.45 0.28
9155 || orf19.4546 || HOL4 || || Putative ion transporter; alkaline induced by Rim101; Plc1-regulated; caspofungin repressed; rat catheter and Spider biofilm induced || 1 -0.26 -0.77 0.00 -0.12 0.08 1.11 -0.38 -0.89 -0.03 0.13 -0.64 0.04 -1.88 -0.40 -0.89 0.20
9156 || orf19.473 || TPO4 || || Putative sperimidine transporter; fungal-specific (no human or murine homolog); Spider biofilm induced; promoter bound by Tec1 and Ndt80; Bcr1-repressed in RPMI a/a biofilms || 1 -0.24 -0.94 -0.13 0.15 -0.81 1.48 -0.22 -0.73 -0.28 -0.10 -0.37 -0.59 -1.22 -1.06 -0.54 -0.31
9157 || orf19.6641 || || || Ortholog of Candida albicans WO-1 : CAWG_01892 || 1 -0.50 -0.38 0.04 -0.11 0.07 0.62 -0.47 -0.17 0.03 -0.73 -0.06 -0.21 -0.23 -0.40 -0.47 -0.27
9158 || orf19.609 || || || Protein of unknown function; white cell specific transcript || 1 -0.97 -0.14 0.04 -0.62 -0.58 1.41 -0.53 -0.46 -0.19 0.00 -0.06 -0.09 -0.26
9159 || orf19.5168 || || || Ortholog(s) have role in maturation of SSU-rRNA and cytosol, nucleolus localization || 1 -0.44 -0.26 0.48 -0.43 -0.14 0.37 -0.62 -0.35 -0.02 -0.00 -0.40 -0.57 -0.10 -0.32 -0.14 -0.29
9160 || orf19.555 || || || Protein similar to S. cerevisiae Cis3p, which has a role cell-wall-related processes; predicted Kex2p substrate; possibly an essential gene, disruptants not obtained by UAU1 method || 1 -0.19 0.07 -0.06 -0.23 -0.08 0.41 -0.23 -0.24 -0.30 -0.37 -0.99 -0.36 -0.38 -0.57 -0.19 0.51
9161 || orf19.372 || || || Putative protein of unknown function; Hap43p-repressed gene || 1 0.16 -0.25 -0.26 -0.23 -0.09 0.66 0.08 0.23 -0.26 -0.33 0.11 -0.25 -0.24 -0.22 0.96 0.83
9162 || orf19.5634 || FRP1 || || Ferric reductase; alkaline-induced by Rim101; iron-chelation-induced by CCAAT-binding factor; fluconazole-repressed; ciclopirox-, hypoxia-, Hap43-induced; colony morphology-related regulation by Ssn6; Spider and flow model biofilm induced || 1 -0.25 -0.00 0.04 -0.25 0.93 1.50 0.12 0.53 -1.64 -0.74 0.01 -0.29 0.81 0.14 0.85 1.48
9163 || orf19.6491 || || || Ortholog of Candida albicans WO-1 : CAWG_05572 || 1 -0.64 -0.38 -1.04 0.05 0.72 0.79 -0.45 -1.31 -0.07 -0.22 -0.98 -0.51 1.15
9164 || orf19.909 || STP4 || || C2H2 transcription factor; induced in core caspofungin response; colony morphology-related gene regulation by Ssn6; induced by 17-beta-estradiol, ethynyl estradiol; rat catheter and Spider biofilm induced || 1 -1.49 -1.25 -1.11 0.02 0.85 2.12 0.17 -1.31 -2.72 -0.82 0.14 -0.51 -1.66 -0.60 1.39 0.10
9165 || orf19.909 || STP4 || || C2H2 transcription factor; induced in core caspofungin response; colony morphology-related gene regulation by Ssn6; induced by 17-beta-estradiol, ethynyl estradiol; rat catheter and Spider biofilm induced || 1 -0.70 -0.76 -0.89 0.37 1.12 1.95 0.50 -0.77 -1.57 -0.48 0.64 -0.30 -1.35 0.05 1.74 0.23
9166 || orf19.6507 || || || Putative curved DNA-binding protein orthologous to S. pombe Cdb4; stationary phase enriched protein; rat catheter and Spider biofilm repressed || 1 -0.11 -0.26 -0.27 -0.23 0.79 0.50 -0.03 0.07 -0.38 0.41 0.23 0.34 -0.23 -0.24 0.27 0.37
9167 || orf19.741 || || || Dubious open reading frame || 1 0.09 0.02 -0.99 1.26 1.05 -0.81 -0.81 -1.56 0.94 1.04 1.08 0.55 0.99
9168 || orf19.3666 || || || Predicted debranching enzyme-associated ribonuclease; rat catheter biofilm induced || 1 0.23 -0.19 -0.03 -0.62 0.32 0.11 -0.10 0.05 -0.35 0.33 0.38 0.66 -0.19 0.40 0.11 0.51
9169 || orf19.3647 || SEC8 || || Predicted subunit of the exocyst complex, involved in exocytosis; localizes to a crescent on the surface of the hyphal tip || 1 0.25 0.32 -0.22 -0.08 0.55 -0.10 0.05 -0.16 -0.30 -0.01 0.52 0.39 -0.28 0.24 0.20 0.39
9170 || orf19.2370 || DSL1 || || Protein similar to S. cerevisiae Dsl1p, which is a member of the t-SNARE complex of the endoplasmic reticulum || 1 0.20 0.17 -0.17 0.01 0.37 0.17 -0.17 -0.29 -0.40 0.07 0.30 0.68 -0.09 0.35 0.30 0.80
9171 || orf19.2370 || DSL1 || || Protein similar to S. cerevisiae Dsl1p, which is a member of the t-SNARE complex of the endoplasmic reticulum || 1 0.09 0.27 0.01 -0.11 0.29 0.07 -0.14 -0.38 -0.27 -0.32 0.46 0.52 -0.03 0.32 0.40 0.76
9172 || orf19.904 || || || Ortholog(s) have cytosol, nucleus localization || 1 0.60 0.46 -0.28 -0.62 0.89 0.89 -0.14 0.03 -0.63 -0.83 1.21 0.71 -0.36 -0.21 0.44 1.09
9173 || orf19.7482 || || || Ortholog of C. parapsilosis CDC317 : CPAR2_803740, C. dubliniensis CD36 : Cd36_25640, Lodderomyces elongisporus NRLL YB-4239 : LELG_00467 and Candida orthopsilosis Co 90-125 : CORT_0A03760 || 1 0.77 0.72 -0.21 -0.42 0.43 0.64 0.01 -0.10 -0.26 -0.22 0.71 0.95 -0.09 0.08 0.37 0.95
9174 || orf19.7038 || || || Ortholog(s) have phosphatidylinositol-3-phosphate binding activity, role in protein targeting to vacuole and cytoplasm, nucleus localization || 1 0.49 0.24 -0.35 -0.10 0.47 0.55 -0.17 -0.15 -0.43 -0.11 0.12 0.30 0.03 -0.06 0.40 0.53
9175 || orf19.5499 || || || Ortholog(s) have 4-hydroxyphenylpyruvate dioxygenase activity and role in aromatic amino acid family biosynthetic process || 1 0.16 0.09 0.30 -0.43 0.12 0.50 0.09 -0.29 -0.44 -0.16 0.47 0.52 0.15 -0.04 0.40 0.48
9176 || orf19.4689 || PGA57 || || Putative GPI-anchored protein; Hap43p-induced gene || 1 0.03 0.02 -0.20 0.28 0.44 1.14 -0.30 -0.61 -1.19 -0.21 0.65 0.84 0.01 0.34 0.19 0.39
9177 || orf19.878 || NBN1 || || Subunit of the NuA4 histone acetyltransferase complex; Plc1p-regulated || 1 -0.19 -0.19 0.21 0.10 0.38 0.14 -0.10 -0.10 -0.19 -0.04 0.55 0.48 -0.03 0.26 0.29 0.15
9178 || orf19.7347 || || || Ortholog(s) have ubiquitin-protein ligase activity, role in ER-associated ubiquitin-dependent protein catabolic process and endoplasmic reticulum membrane localization || 1 -0.01 0.02 -0.02 -0.20 0.05 0.71 -0.29 0.01 -0.30 -0.00 1.09 1.27 0.30 0.42 0.47 0.70
9179 || orf19.5406 || || || Predicted plasma membrane associated protein phosphatase; required for normal filamentous growth; mRNA binds She3 and is localized to hyphal tips || 1 0.07 -0.03 0.17 0.36 -0.08 0.39 -0.14 -0.18 -0.06 -0.31 1.25 1.08 0.32 -0.29 0.41 0.70
9180 || orf19.7165 || MED9 || || RNA polymerase II mediator complex subunit; Hap43p-repressed gene || 1 -0.14 -0.43 -0.27 0.03 0.25 0.17 -0.22 0.04 0.16 -0.20 0.33 0.49 -0.28 0.17 -0.33 0.55
9181 || orf19.1070 || || || Ortholog(s) have cytoplasm localization || 1 -0.09 -0.05 -0.31 0.00 0.11 0.59 -0.28 -0.38 -0.13 -0.57 0.24 0.73 -0.02 0.56 -0.31 0.88
9182 || orf19.6448 || || || Protein of unknown function; Spider biofilm repressed || 1 -0.14 -0.12 0.10 -0.22 0.19 0.10 -0.30 -0.24 -0.15 -0.10 0.20 0.24 -0.07 0.05 0.08 0.64
9183 || orf19.2099 || HIR1 || || Component of the HIR complex, a nucleosome assembly factor involved in chromatin formation; involved in regulation of white-opaque switching frequency || 1 -0.30 -0.21 0.17 0.04 0.49 0.78 -0.71 -0.59 -0.41 -0.57 0.17 0.40 -0.35 0.02 -0.17 1.06
9184 || orf19.6075 || || || Putative CCR4-Not complex transcription factor; ortholog of S. cerevisiae Cdc36; Hap43-repressed gene || 1 -0.05 0.09 -0.02 -0.14 0.34 0.48 -0.34 -0.17 -0.22 -0.02 0.27 0.36 0.03 -0.11 0.00 0.57
9185 || orf19.4690 || || || NRAMP metal ion transporter domain-containing protein; induced by nitric oxide independent of Yhb1; flow model biofilm induced; rat catheter biofilm repressed || 1 -0.18 0.08 0.66 0.12 1.25 0.47 -0.35 -0.70 -0.34 -0.82 -0.10 0.90 0.04 -0.33 0.15 1.05
9186 || orf19.2290 || TOR1 || || Protein similar to TOR family phosphatidylinositol kinases; mutation confers resistance to rapamycin; involved in regulation of ribosome biogenesis, starvation response, and adhesion || 1 -0.22 -0.28 0.11 0.17 0.43 0.40 -0.10 -0.10 0.09 -0.32 -0.07 0.23 -0.09 0.06 0.09 0.35
9187 || orf19.1955 || || || Ortholog(s) have palmitoyltransferase activity, role in protein palmitoylation, protein targeting to membrane and endoplasmic reticulum palmitoyltransferase complex, extrinsic to endoplasmic reticulum membrane localization || 1 -0.73 -0.73 0.07 0.02 0.29 0.22 -0.02 -0.15 -0.00 -0.48 0.39 0.15 -0.17 0.13 0.17 0.58
9188 || orf19.1955 || || || Ortholog(s) have palmitoyltransferase activity, role in protein palmitoylation, protein targeting to membrane and endoplasmic reticulum palmitoyltransferase complex, extrinsic to endoplasmic reticulum membrane localization || 1 -0.64 -0.59 0.24 0.02 0.24 0.30 -0.07 -0.33 -0.15 -0.42 0.22 0.22 -0.27 -0.16 -0.11 0.47
9189 || orf19.7177 || KAP120 || || Putative karyopherin; mutation confers hypersensitivity to cytochalasin D || 1 -0.30 -0.24 0.20 0.00 0.17 0.36 -0.08 -0.16 0.07 -0.08 -0.10 0.40 -0.60 -0.08 -0.08 0.64
9190 || orf19.3405 || ZCF18 || || Putative Zn(II)2Cys6 transcription factor; heterozygous null mutant displays sensitivity to virgineone and decreased colonization of mouse kidneys || 1 -0.44 -0.39 0.06 -0.11 0.23 0.29 -0.03 -0.02 -0.06 -0.33 0.20 0.34 -0.39 -0.05 0.22 0.64
9191 || orf19.5247 || || || Ortholog(s) have cytoplasm localization || 1 -0.22 -0.35 0.02 -0.00 0.15 0.44 -0.01 0.08 -0.13 -0.17 0.13 0.44 -0.35 0.24 0.43 0.81
9192 || orf19.1636 || STE50 || || Protein with sterile alpha motif (SAM) and Ras-associated domain (RAD); similar to S. cerevisiae Rad50p, which is involved in signal transduction via interaction with and regulation of MAPKKK || 1 -0.35 -0.35 0.07 -0.12 0.30 0.55 -0.04 -0.02 0.16 -0.02 -0.38 0.58 -0.25 -0.02 0.71 0.51
9193 || orf19.89 || PEX7 || || Ortholog(s) have peroxisome matrix targeting signal-2 binding activity, role in fatty acid metabolic process, protein import into peroxisome matrix, docking and cytosol, nucleus, peroxisome localization || 1 -0.30 -0.18 0.06 -0.05 0.13 0.17 -0.20 -0.01 -0.09 -0.37 -0.23 0.53 -0.14 -0.30 0.32 0.56
9194 || orf19.4575 || || || Ortholog(s) have mitochondrion localization || 1 -0.31 -0.57 0.12 0.50 -0.04 0.77 -0.43 -0.54 -0.52 -0.68 -0.10 0.68 -0.09 -0.06 0.24 0.49
9195 || orf19.6339 || NRG2 || || Transcription factor; transposon mutation affects filamentous growth || 1 -0.85 -1.84 0.00 -0.62 -0.46 -0.37 -2.14 0.14 1.08 2.01 -0.32 0.85 1.38
9196 || orf19.6643 || MCT1 || || Putative malonyl-CoA acyl carrier protein acyltransferase || 1 -1.91 -1.72 -0.28 -0.78 0.02 0.47 -0.33 -0.46 -1.66 -0.69 1.08 1.26 0.17 0.44 0.93 1.28
9197 || orf19.5537 || WSC2 || || Putative cell wall integrity and stress response protein; mRNA binds She3; Spider biofilm induced || 1 -0.83 -0.67 -0.08 -0.20 -0.50 0.33 -0.26 -0.82 -0.62 -0.79 -0.03 0.57 0.38 -0.13 1.12 0.40
9198 || orf19.3869 || || || Protein of unknown function; regulated by Tsa1, Tsa1B in minimal media at 37 degrees C; shows colony morphology-related gene regulation by Ssn6; Spider biofilm induced || 1 -1.64 -1.75 -0.69 -1.08 -0.14 0.82 -0.22 -0.84 -0.69 -1.04 0.03 1.17 0.72 0.54 1.63 0.65
9199 || orf19.2423 || ZCF11 || || Zn(II)2Cys6 transcription factor; required for wild-type filamentous growth; mRNA binds She3 || 1 -0.71 -0.58 -0.15 -0.18 0.02 0.02 -0.33 -0.26 -0.15 -0.20 0.16 0.35 0.25 -0.09 0.37 0.12
9200 || orf19.3222 || || || Predicted vacuolar protein; rat catheter biofilm repressed; flow model biofilm repressed || 1 -0.39 -0.56 -0.39 -0.29 -0.11 0.10 -0.32 -0.28 -0.46 -0.37 -0.23 0.53 0.06 0.29 0.23 0.09
9201 || orf19.5729 || FGR17 || || Putative DNA-binding transcription factor; has zinc cluster DNA-binding motif; lacks an ortholog in S. cerevisiae; transposon mutation affects filamentous growth; Hap43p-repressed gene || 1 -0.80 -0.63 -0.34 -0.53 -0.05 0.59 -0.58 -0.64 0.03 -1.21 -0.16 0.27 0.13 0.01 0.27 0.97
9202 || orf19.2743 || || || Ortholog(s) have RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription, more || 1 -0.34 -0.37 -0.01 -0.11 -0.11 0.16 -0.68 -0.32 -0.06 -0.57 -0.03 0.32 -0.23 -0.11 0.23 0.57
9203 || orf19.4031 || || || Ortholog(s) have cytoplasm localization || 1 -0.77 -0.57 -0.49 -0.78 -0.07 -0.25 -0.63 -0.06 -0.08 -0.53 0.05 0.45 -0.20 -0.22 0.60 0.82
9204 || orf19.5357 || AKL1 || || Putative serine/threonine protein kinase; induced during the mating process || 1 -0.33 -0.24 -0.24 -0.29 -0.21 -0.20 0.02 -0.12 -0.29 -0.45 -0.04 0.11 -0.18 0.11 0.58 0.51
9205 || orf19.6868 || || || Putative NADPH-dependent methylglyoxal reductase; homozygous transposon insertion causes decreased colony wrinkling under filamentous growth-inducing conditions, but does not block true hyphal formation in liquid media || 1 -0.37 -0.42 -0.39 -0.56 -0.08 -0.11 -0.59 -0.45 -0.43 -0.67 0.12 0.57 -0.50 0.06 0.40 0.56
9206 || orf19.2665 || MSN5 || || Predicted karyopherin involved in nuclear import and export of proteins; flow model biofilm induced; Spider biofilm induced || 1 -0.46 -0.53 -0.45 -0.71 -0.27 -0.32 -0.34 -0.37 -0.44 -0.82 0.12 0.23 -0.42 0.34 0.40 0.50
9207 || orf19.2991 || HOL1 || || Putative MFS transporter; regulated by Nrg1; macrophage/pseudohyphal-repressed; induced by alpha pheromone in SpiderM medium; possibly an essential gene, disruptants not obtained by UAU1 method || 1 -0.50 -1.69 -0.42 -0.28 -0.46 -0.86 -0.47 -1.20 0.08 0.68 -0.72 0.89 1.51
9208 || orf19.7229 || IML2 || || Protein of unknown function; early-stage flow model biofilm induced; Hap43-repressed; Spider biofilm repressed || 1 -0.61 -0.57 -0.37 -0.12 0.18 -0.27 -0.33 -0.52 -0.38 -0.56 0.35 0.22 -0.54 -0.04 0.64 0.86
9209 || orf19.3342 || || || Ortholog(s) have role in protein deubiquitination and cytoplasm, nucleus localization || 1 -0.11 -0.33 -0.09 -0.23 0.31 0.06 -0.30 -0.21 -0.26 -0.37 0.20 0.13 -0.31 -0.04 0.46 0.70
9210 || orf19.6595 || RTA4 || || Protein similar to S. cerevisiae Rsb1p, involved in fatty acid transport; transposon mutation affects filamentous growth; alkaline downregulated; caspofungin induced; possibly an essential gene; Hap43p-repressed || 1 -0.07 -0.57 -0.12 -0.72 -0.06 0.58 -0.93 -0.66 -0.46 -0.54 -0.29 0.68 -1.06 0.40 0.58 0.98
9211 || orf19.3537 || || || Putative sulfiredoxin; regulated by Tsa1, Tsa1B in minimal media at 37 degrees C; flow model biofilm induced; Spider biofilm induced || 1 -0.15 -0.23 -0.33 -0.43 0.88 0.29 0.05 -0.19 -0.11 -1.51 0.45 0.48 0.37 0.95 1.11 0.75
9212 || orf19.3537 || || || Putative sulfiredoxin; regulated by Tsa1, Tsa1B in minimal media at 37 degrees C; flow model biofilm induced; Spider biofilm induced || 1 -0.21 -0.14 -0.27 -0.01 0.44 0.01 -0.04 -0.21 -0.32 -1.04 0.13 0.32 -0.19 0.31 0.67 0.92
9213 || orf19.1220 || RVS167 || || SH3-domain- and BAR domain-containing protein involved in endocytosis; null mutant exhibits defects in hyphal growth, virulence, cell wall integrity, and actin patch localization; cosediments with phosphorylated Myo5p || 1 -0.17 -0.17 -0.20 -0.27 0.29 0.22 0.01 -0.17 -0.35 -0.73 0.02 -0.10 0.02 0.15 0.61 0.44
9214 || orf19.372 || || || Putative protein of unknown function; Hap43p-repressed gene || 1 -0.34 -0.31 -0.48 -0.31 0.23 0.99 0.14 0.01 -0.22 -0.31 0.48 0.18 -0.01 0.23 1.15 0.81
9215 || orf19.1267 || || || Ortholog of S. cerevisiae : CAJ1, C. glabrata CBS138 : CAGL0L00957g, C. dubliniensis CD36 : Cd36_45380, C. parapsilosis CDC317 : CPAR2_500650 and Candida tenuis NRRL Y-1498 : CANTEDRAFT_132273 || 1 -0.35 -0.41 -0.38 -0.34 0.21 0.96 0.25 -0.53 -0.77 -0.80 0.51 0.21 0.07 0.25 1.84 0.91
9216 || orf19.1267 || || || Ortholog of S. cerevisiae : CAJ1, C. glabrata CBS138 : CAGL0L00957g, C. dubliniensis CD36 : Cd36_45380, C. parapsilosis CDC317 : CPAR2_500650 and Candida tenuis NRRL Y-1498 : CANTEDRAFT_132273 || 1 -0.06 0.04 -0.13 -0.08 0.41 0.76 0.18 -0.33 -0.37 -0.66 0.48 0.43 0.21 0.21 1.80 0.86
9217 || orf19.6773 || ECM29 || || Putative scaffold protein; assists in association of the proteasome core particle with the regulatory particle; ortholog of S. cerevisiae Ecm29; transposon mutation affects filamentous growth; flow model biofilm repressed || 1 0.04 -0.03 -0.74 -0.54 0.57 0.07 0.09 -0.19 -0.31 -0.41 0.55 0.31 -0.61 -0.16 1.49 0.97
9218 || orf19.457 || || || Ortholog(s) have ubiquitin-specific protease activity, role in protein deubiquitination, ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway and cytosol localization || 1 0.03 0.06 -0.30 -0.59 0.53 0.32 0.00 -0.10 0.02 -0.50 0.22 0.48 -0.22 0.19 0.65 0.37
9219 || orf19.75 || || || Predicted exocyst component; ortholog of S. cerevisiae Sec5p; merged with orf19.74 in Assembly 21 || 1 -0.09 -0.02 -0.47 -0.53 0.51 0.31 0.26 -0.24 -0.12 -0.19 0.04 0.70 0.09 0.27 0.63 1.00
9220 || orf19.6643 || MCT1 || || Putative malonyl-CoA acyl carrier protein acyltransferase || 1 -0.27 -0.50 -0.29 -0.43 0.05 0.08 -0.36 -0.35 -0.52 -0.31 0.14 1.12 -0.00 0.09 0.50 0.73
9221 || orf19.2343 || VPS23 || || ESCRT I protein sorting complex protein; involved in proteolytic activation of Rim101, which regulates pH response; ortholog of S. cerevisiae Stp22/Vps23 || 1 -0.41 -0.35 -0.26 -0.41 0.17 0.18 -0.11 0.00 -0.20 -0.10 0.15 0.81 -0.06 0.01 0.28 0.56
9222 || orf19.4800 || RIM20 || || Protein involved in the pH response pathway; binds to the transcription factor Rim101 and may serve as a scaffold to facilitate the C-terminal proteolytic cleavage that activates Rim101; required for alkaline pH-induced hyphal growth || 1 -0.17 -0.23 -0.35 -0.56 0.47 0.33 -0.02 0.06 -0.24 -0.57 0.47 0.52 -0.47 0.39 0.83 1.09
9223 || orf19.4800 || RIM20 || || Protein involved in the pH response pathway; binds to the transcription factor Rim101 and may serve as a scaffold to facilitate the C-terminal proteolytic cleavage that activates Rim101; required for alkaline pH-induced hyphal growth || 1 -0.33 -0.32 -0.58 -0.73 0.42 0.32 -0.09 -0.43 0.22 -0.42 0.53 0.69 -0.47 0.40 0.69 1.09
9224 || orf19.2499 || || || Putative peptidyl-prolyl cis-trans isomerase || 1 -0.62 -0.49 -1.09 -1.01 0.41 0.59 0.02 -0.06 -0.45 -0.24 1.22 1.29 -0.22 0.19 1.05 1.15
9225 || orf19.6875 || VPS35 || || Putative role in vacuolar sorting; downregulated in biofilm; induced upon adherence to polystyrene || 1 -0.27 -0.41 -0.64 -0.71 0.42 0.10 -0.19 -0.21 -0.26 -0.28 0.46 0.56 -0.12 0.32 0.82 0.92
9226 || orf19.6875 || VPS35 || || Putative role in vacuolar sorting; downregulated in biofilm; induced upon adherence to polystyrene || 1 -0.46 -0.42 -0.37 -0.43 0.31 0.12 -0.26 -0.25 -0.26 -0.26 0.32 0.35 -0.06 0.16 0.77 0.71
9227 || orf19.3071 || MIH1 || || Putative protein phosphatase of the PTP family (tyrosine-specific); ortholog of S. cerevisiae Mih1; mRNA binds She3 || 1 -1.02 -0.73 -0.61 -1.05 0.67 0.22 -0.85 -0.57 -0.67 -0.62 1.22 1.17 -0.38 0.12 1.64 0.78
9228 || orf19.3050 || AGE1 || || Putative GTPase activator; induced in low iron; rat catheter biofilm repressed || 1 -0.33 -0.22 -0.06 -0.59 0.22 0.29 -0.51 -0.34 -0.43 -0.00 0.69 0.51 -0.11 0.04 0.41 0.28
9229 || orf19.3498 || || || Ortholog of C. dubliniensis CD36 : Cd36_62270, C. parapsilosis CDC317 : CPAR2_602240, Candida tenuis NRRL Y-1498 : CANTEDRAFT_114419 and Debaryomyces hansenii CBS767 : DEHA2E04884g || 1 -0.45 -0.61 -0.40 -0.65 0.62 0.54 -0.18 -0.20 -0.52 0.07 0.84 0.87 -0.34 -0.02 0.60 0.43
9230 || orf19.3319 || || || Putative thioredoxin; Spider biofilm repressed || 1 -0.22 -0.36 -0.64 -0.55 0.31 0.19 -0.59 -0.10 -0.59 -0.17 0.83 0.60 -0.64 -0.30 0.59 0.70
9231 || orf19.730 || || || Ortholog(s) have Rho GTPase activator activity and role in establishment or maintenance of actin cytoskeleton polarity, small GTPase mediated signal transduction || 1 -0.31 -0.18 -0.32 -0.69 0.16 -0.24 -0.06 -0.35 -0.34 -0.67 0.44 0.21 -0.44 -0.35 0.25 1.01
9232 || orf19.729.1 || RGD3 || || Putative Rho GTPase activating protein; fungal-specific (no human or murine homolog) || 1 -0.06 -0.08 -0.20 -0.58 0.33 -0.25 -0.09 -0.43 -0.35 -0.61 0.29 0.27 -0.51 -0.32 0.38 0.85
9233 || orf19.729.1 || RGD3 || || Putative Rho GTPase activating protein; fungal-specific (no human or murine homolog) || 1 -0.09 -0.01 0.03 -0.47 0.63 -0.24 0.30 -0.12 -0.17 -0.39 0.56 0.33 -0.03 -0.34 0.48 0.98
9234 || orf19.730 || || || Ortholog(s) have Rho GTPase activator activity and role in establishment or maintenance of actin cytoskeleton polarity, small GTPase mediated signal transduction || 1 0.14 0.09 -0.25 -0.57 0.57 -0.14 0.15 -0.19 -0.22 -0.48 0.74 0.58 -0.04 -0.08 0.65 0.99
9235 || orf19.1999 || || || Protein of unknown function; transcript detected on high-resolution tiling arrays || 1 -0.24 -0.14 -0.66 -0.91 0.53 -0.44 0.19 0.06 -0.65 -0.59 1.29 0.77 -0.64 -0.52 0.17 1.17
9236 || orf19.1999 || || || Protein of unknown function; transcript detected on high-resolution tiling arrays || 1 -0.29 -0.33 -0.99 -1.04 0.97 0.18 -0.04 -0.07 -0.76 -0.84 1.58 1.18 -0.86 -0.07 0.17 1.33
9237 || orf19.4251 || ZCF22 || || Predicted Zn(II)2Cys6 transcription factor || 1 -0.49 -0.52 -0.96 -0.69 0.64 -0.05 0.60 -0.56 -0.35 -0.58 0.87 0.84 -0.06 0.12 0.46 1.04
9238 || orf19.3523 || CRK1 || || Protein kinase of the Cdc2 subfamily involved in hyphal development, virulence; promotes hyphal development independently of Cph1 and Efg1; functionally complements pheromone hypersensitivity of S. cerevisiae sgv1 mutant; Hap43p-repressed || 1 -0.25 -0.46 -0.11 -0.88 0.32 0.26 0.23 0.05 -0.34 -0.22 0.75 0.30 0.19 -0.19 0.47 1.04
9239 || orf19.2261 || || || Ortholog(s) have RNA binding activity, role in mRNA splicing, via spliceosome and U2 snRNP, U2-type prespliceosome, cytosol localization || 1 -0.33 -0.09 -0.88 -1.60 0.44 0.70 -0.03 -0.22 -0.63 -1.33 1.55 0.78 0.29 -0.23 0.37 1.66
9240 || orf19.2261 || || || Ortholog(s) have RNA binding activity, role in mRNA splicing, via spliceosome and U2 snRNP, U2-type prespliceosome, cytosol localization || 1 -0.22 -0.35 -0.78 -1.43 0.28 0.43 -0.28 -0.25 -0.68 -1.39 1.06 0.49 -0.02 -0.49 0.34 1.48
9241 || orf19.6638 || PTC4 || || Type PP2C serine/threonine phosphatase; localized to mitochondria; mutation causes sensitivity to sodium, potassium and azole drugs; decreased expression in hyphae compared to yeast-form cells || 1 -0.52 -0.36 -0.66 -0.88 0.02 0.28 -0.51 -0.34 -0.58 -0.50 0.83 -0.08 -0.11 -0.15 0.27 0.90
9242 || orf19.6638 || PTC4 || || Type PP2C serine/threonine phosphatase; localized to mitochondria; mutation causes sensitivity to sodium, potassium and azole drugs; decreased expression in hyphae compared to yeast-form cells || 1 -0.17 -0.16 -0.66 -0.56 0.06 0.14 -0.48 -0.19 -0.85 -0.60 0.85 0.05 0.01 -0.34 0.34 0.64
9243 || orf19.4911 || || || BED zinc finger protein; predicted DNA binding protein; Spider biofilm repressed || 1 -0.42 -0.82 -0.71 -0.56 -0.22 0.39 -0.40 -0.34 -1.31 -1.17 1.32 0.77 0.08 -0.24 0.88 1.18
9244 || orf19.7347 || || || Ortholog(s) have ubiquitin-protein ligase activity, role in ER-associated ubiquitin-dependent protein catabolic process and endoplasmic reticulum membrane localization || 1 -0.02 -0.02 -0.38 -0.27 -0.02 0.34 0.02 -0.02 -1.15 -0.76 1.38 0.68 0.10 -0.35 0.71 0.60
9245 || orf19.1027 || PDR16 || || Phosphatidylinositol transfer protein; induction correlates with CDR1, CDR2 overexpression/azole resistance; fluphenazine, 17-beta-estradiol, ethynyl estradiol, NO induced; farnesol-downregulated in biofilm; rat catheter biofilm induced || 1 -0.28 -0.32 -0.61 -0.29 0.12 1.11 0.13 0.40 -0.96 -0.92 0.90 0.73 -0.11 0.24 0.39 0.90
9246 || orf19.1027 || PDR16 || || Phosphatidylinositol transfer protein; induction correlates with CDR1, CDR2 overexpression/azole resistance; fluphenazine, 17-beta-estradiol, ethynyl estradiol, NO induced; farnesol-downregulated in biofilm; rat catheter biofilm induced || 1 -0.08 -0.74 -0.73 -0.43 0.00 0.98 0.09 0.26 -1.09 -1.02 1.07 0.19 -0.38 0.06 0.61 0.54
9247 || orf19.6660 || || || Protein of unknown function; mRNA binds to She3; Hap43-repressed; rat catheter and flow model biofilm induced || 1 -0.88 -0.85 -1.07 -0.56 0.32 0.92 0.31 0.12 -0.89 -1.23 1.39 -0.34 -0.42 -0.49 0.29 0.59
9248 || orf19.6660 || || || Protein of unknown function; mRNA binds to She3; Hap43-repressed; rat catheter and flow model biofilm induced || 1 -0.50 -0.55 -0.80 -0.40 0.44 1.13 0.16 0.15 -1.04 -1.22 1.32 -0.11 -0.40 -0.11 0.28 1.06
9249 || orf19.6660 || || || Protein of unknown function; mRNA binds to She3; Hap43-repressed; rat catheter and flow model biofilm induced || 1 -0.40 -0.34 -1.14 -0.55 0.28 0.86 0.18 0.19 -0.91 -1.21 1.03 -0.42 -0.34 -0.16 0.16 1.04
9250 || orf19.1105.3 || || || Protein of unknown function || 1 0.66 -0.38 -0.96 0.03 -0.10 0.28 -0.24 -0.57 0.54 -0.37 0.47 0.87
9251 || orf19.4494 || KTR2 || || Mannosyltransferase; transcription elevated in chk1, nik1, and sln1 homozygous null mutants; fungal-specific (no human or murine homolog); possibly an essential gene, disruptants not obtained by UAU1 method || 1 0.17 -0.33 -0.18 -0.20 0.05 0.06 -0.30 0.03 -0.26 -0.43 0.41 0.57 -0.37 0.27 0.41 0.63
9252 || orf19.3198 || OBPA || || Similar to oxysterol binding protein; non-sex gene located within the MTLa mating-type-like locus; Plc1p-regulated || 1 -0.05 -0.07 -0.50 -0.56 0.18 0.27 -0.14 -0.24 -0.37 -0.79 0.24 0.20 -0.39 -0.05 0.78 -0.01
9253 || orf19.5671 || || || Ortholog(s) have role in actin cortical patch assembly, septin cytoskeleton organization and cellular bud neck, cellular bud tip, mating projection base, mating projection tip localization || 1 -0.03 -0.24 0.21 -0.09 0.32 0.35 -0.46 -0.12 -0.26 -0.19 0.11 0.09 0.05 -0.31 0.52 0.01
9254 || orf19.1719 || SGA1 || || Putative glucoamylase; induced in oralpharyngeal candidasis; rat catheter and Spider biofilm induced || 1 -0.17 -0.36 0.43 0.12 0.42 0.70 -0.38 -0.18 -0.17 -0.24 0.83 0.83 -0.60 -0.62 0.70 0.50
9255 || orf19.1621 || GPA2 || || G-protein alpha subunit; regulates filamentous growth, copper resistance; involved in cAMP-mediated glucose signaling; reports differ on role in cAMP-PKA pathway, MAP kinase cascade; Gpr1 C terminus binds Gpa2; regulates HWP1 and ECE1 || 1 -0.19 -0.46 -0.06 -0.00 0.50 0.36 -0.47 0.08 -0.18 -0.12 0.28 0.38 -0.76 -0.05 0.31 0.28
9256 || orf19.6797 || || || Ortholog of C. dubliniensis CD36 : Cd36_86960, C. parapsilosis CDC317 : CPAR2_808800, Candida tenuis NRRL Y-1498 : CANTEDRAFT_113621 and Debaryomyces hansenii CBS767 : DEHA2F02486g || 1 -0.06 -0.17 -0.21 0.18 0.41 0.40 -0.40 0.27 -0.25 -0.37 0.18 0.31 -0.21 -0.03 0.27 0.22
9257 || orf19.2662 || || || Predicted ORF of unknown function; overlaps TLO34/orf19.2661 || 1 -0.41 -0.46 -0.17 0.00 0.22 0.55 -0.22 0.05 -0.16 -0.43 0.29 0.13 -0.50 -0.47 -0.05 -0.00
9258 || orf19.3482 || || || Ortholog(s) have NAD+ diphosphatase activity, role in NADH metabolic process and cytosol, nucleus, peroxisome localization || 1 -0.19 -0.45 -0.36 -0.33 0.28 0.24 -0.23 -0.12 -0.50 -0.18 0.30 0.29 -0.55 -0.76 0.66 0.10
9259 || orf19.4088 || GLO2 || || Ortholog(s) have hydroxyacylglutathione hydrolase activity, role in cellular carbohydrate metabolic process, methylglyoxal catabolic process to D-lactate and cytosol, mitochondrion, nucleus localization || 1 -0.65 -0.73 -0.88 -0.92 1.10 0.97 -0.34 -0.58 -0.72 -0.60 0.19 0.17 -1.93 -1.18 0.81 0.21
9260 || orf19.4088 || GLO2 || || Ortholog(s) have hydroxyacylglutathione hydrolase activity, role in cellular carbohydrate metabolic process, methylglyoxal catabolic process to D-lactate and cytosol, mitochondrion, nucleus localization || 1 -0.39 -0.25 -0.52 -0.31 1.30 1.07 -0.11 -0.14 -0.29 -0.31 0.54 0.49 -1.39 -0.95 0.99 -0.24
9261 || orf19.2662 || || || Predicted ORF of unknown function; overlaps TLO34/orf19.2661 || 1 -0.07 -0.14 -0.17 0.01 0.38 0.66 -0.08 0.32 -0.22 -0.36 0.49 0.35 -0.49 -0.60 0.06 0.32
9262 || orf19.820 || SDS22 || || Putative protein serine-threonine phosphatase; macrophage/pseudohyphal-repressed || 1 0.08 -0.04 -0.30 -0.44 0.62 0.79 -0.05 0.13 -0.21 -0.46 0.58 0.54 -0.94 -0.26 0.24 0.07
9263 || orf19.820 || SDS22 || || Putative protein serine-threonine phosphatase; macrophage/pseudohyphal-repressed || 1 0.19 0.14 0.11 -0.26 0.72 0.82 -0.05 0.23 0.04 -0.26 0.64 0.34 -0.43 -0.54 0.28 -0.18
9264 || orf19.3016 || || || Ortholog(s) have role in meiotic chromosome segregation and cytosol, nucleus localization || 1 0.30 0.17 -0.44 -0.52 1.26 1.43 -0.31 -0.24 -0.59 -0.36 0.88 0.59 -1.18 -1.83 0.52 0.11
9265 || orf19.904 || || || Ortholog(s) have cytosol, nucleus localization || 1 0.24 0.26 -0.39 -0.62 0.55 0.61 -0.20 -0.19 -0.65 -0.74 0.87 0.02 -0.94 -1.02 0.26 0.72
9266 || orf19.4614 || || || Adapter protein for pexophagy and the cytoplasm-to-vacuole targeting (Cvt) pathway; Spider biofilm induced || 1 0.10 0.03 -0.42 -0.56 0.73 0.28 -0.29 -0.49 -0.17 -0.49 -0.35 0.26 -0.46 -0.11 0.92 0.20
9267 || orf19.7124 || RVS161 || || Protein required for endocytosis; contains a BAR domain, which is found in proteins involved in membrane curvature; null mutant exhibits defects in hyphal growth, virulence, cell wall integrity, and actin patch localization || 1 -0.13 -0.11 -0.27 -0.41 0.42 0.32 -0.24 -0.46 -0.31 -0.36 -0.05 0.22 -0.70 0.07 0.69 0.22
9268 || orf19.3988 || || || Putative adhesin-like protein; induced by Mnl1 under weak acid stress; rat catheter and Spider biofilm induced || 1 -0.62 -0.69 -0.66 -0.34 1.69 1.64 -0.62 -1.05 -1.10 -0.76 -0.90 0.22 -1.25 0.61 1.78 0.54
9269 || orf19.3187 || ZNC1 || || Zn(2)-Cys(6) transcription factor; regulated by Gcn2 and Gcn4; gene located in zinc cluster region of Chromosome 5, near the MTL locus; required for yeast cell adherence to silicone substrate; Spider biofilm induced || 1 -0.41 -0.18 -0.30 -0.39 0.45 0.41 -0.38 -0.59 -0.20 -0.23 -0.51 0.32 -0.53 0.13 0.43 0.24
9270 || orf19.4423 || || || Putative glucosyltransferase; localized to the mitochondrial membrane || 1 -0.32 -0.47 -0.20 -0.20 0.67 0.95 -0.34 -0.33 -0.01 0.14 0.05 0.24 -0.55 0.25 0.82 0.22
9271 || orf19.4423 || || || Putative glucosyltransferase; localized to the mitochondrial membrane || 1 -0.36 -0.34 -0.05 -0.46 0.53 1.09 -0.48 -0.48 -0.24 -0.05 -0.09 0.23 -0.93 -0.10 0.94 0.52
9272 || orf19.4362 || || || Ortholog(s) have role in protein targeting to mitochondrion and mitochondrial outer membrane localization || 1 -0.25 -0.37 -0.25 -0.36 0.28 0.51 -0.37 -0.24 -0.32 0.11 0.13 0.11 -0.58 0.03 0.83 0.09
9273 || orf19.746 || || || Has domain(s) with predicted role in protein transport || 1 -0.27 -0.31 -0.58 -0.59 0.40 0.42 -0.55 -0.89 -0.63 -0.04 -0.05 0.20 -0.04 0.27 1.01 0.37
9274 || orf19.7378 || || || Ortholog(s) have phosphopantothenoylcysteine decarboxylase activity, protein phosphatase inhibitor activity and role in regulation of mitotic cell cycle, response to salt stress || 1 -0.23 -0.20 -0.10 -0.17 0.24 0.51 -0.36 -0.22 -0.18 -0.17 0.57 0.60 -0.05 -0.23 0.67 -0.04
9275 || orf19.2722 || CGR1 || || Negative regulator of yeast-form growth; HSP70 family member; induced by growth cessation at yeast-hyphal transition or in planktonic growth; physically interacts with Msi3p; similar to rat anti-aging gene, SMP30, stationary phase enriched || 1 -0.49 -0.44 -0.57 -0.77 0.87 1.11 -0.46 0.01 0.29 -0.15 0.60 1.09 -0.31 -0.20 0.95 0.31
9276 || orf19.3110 || || || Possible mannosyltransferase; Spider biofilm induced || 1 -0.60 -0.79 -0.78 -0.97 1.23 1.28 -0.57 -0.49 -0.12 0.32 0.47 1.58 -0.74 -0.79 1.11 0.62
9277 || orf19.3110 || || || Possible mannosyltransferase; Spider biofilm induced || 1 -0.05 -0.20 -0.10 -0.26 0.55 0.94 -0.29 -0.43 0.17 0.02 0.26 1.08 -0.31 -0.68 0.46 0.19
9278 || orf19.6382 || || || Putative MRP/CFTR-subfamily ABC transporter; member of multidrug resistance-associated protein (MRP) subfamily of ABC family; similar to S. cerevisiae Bpt1p || 1 -0.07 -0.06 -0.07 0.03 0.86 0.93 0.03 0.07 0.28 0.07 0.21 0.49 -0.22 -0.25 0.76 0.26
9279 || orf19.6944 || PHB1 || || Putative prohibitin; identified in detergent-resistant membrane fraction (possible lipid raft component); predicted N-terminal acetylation; Hap43p-repressed gene || 1 -0.08 -0.18 -0.24 -0.15 1.02 0.87 -0.01 0.12 0.19 0.05 0.18 0.46 -0.36 -0.20 0.92 -0.02
9280 || orf19.6600 || || || Ortholog(s) have phosphatidic acid transporter activity and role in cardiolipin metabolic process, phospholipid transport, positive regulation of phosphatidylcholine biosynthetic process || 1 -0.24 -0.19 -0.18 -0.25 1.37 1.61 0.01 0.19 0.33 -0.01 0.11 0.37 -0.34 0.01 0.88 0.05
9281 || orf19.4817 || RAM2 || || Alpha subunit of heterodimeric protein geranylgeranyltransferase type I and farnesyltransferase; a-specific transcript; lovastatin, fluconazole regulated; GGTase I binds zinc, is Mg-dependent; Cdc42 substrate; rat catheter biofilm repressed || 1 0.31 0.00 -0.31 -0.30 1.23 1.32 -0.41 0.21 0.08 -0.14 0.04 0.21 -0.41 -0.01 0.31 0.03
9282 || orf19.4195 || || || Ortholog of C. dubliniensis CD36 : Cd36_60540, C. parapsilosis CDC317 : CPAR2_602830, Candida tenuis NRRL Y-1498 : CANTEDRAFT_108530 and Debaryomyces hansenii CBS767 : DEHA2F15532g || 1 0.09 -0.18 -0.38 -0.65 0.55 0.75 0.13 0.12 0.08 -0.12 0.10 0.46 -0.52 -0.51 0.32 -0.01
9283 || orf19.5863 || || || Ortholog of C. dubliniensis CD36 : Cd36_84160, Candida tenuis NRRL Y-1498 : cten_CGOB_00085, Debaryomyces hansenii CBS767 : DEHA2B08404g and Pichia stipitis Pignal : PICST_67031 || 1 -0.07 -0.26 -0.47 -1.23 0.96 1.90 -0.61 -0.10 -0.51 -1.32 -0.11 1.41 -0.28 -1.38 1.10 0.11
9284 || orf19.7602 || AHA1 || || Putative Hsp90p co-chaperone; Hap43-repressed; heavy metal (cadmium) stress-induced; oxidative stress-induced via Cap1; rat catheter biofilm induced; flow model biofilm repressed || 1 -0.06 -0.13 -0.27 -0.57 0.54 0.90 0.06 0.26 -0.17 -0.31 0.29 0.40 0.02 -0.37 0.29 -0.02
9285 || orf19.3399 || || || Ortholog(s) have histone binding activity, role in histone exchange and Swr1 complex, cytoplasm localization || 1 -0.18 -0.16 -0.12 -0.48 0.49 0.67 0.14 0.15 0.08 -0.07 0.09 0.28 0.28 -0.47 0.37 0.16
9286 || orf19.3826 || || || Predicted transmembrane protein with a role in cell wall polymer composition; Plc1-regulated; Spider biofilm induced || 1 -0.14 0.18 -0.16 -0.33 1.09 1.61 0.64 0.01 -0.01 -0.75 -0.18 -0.07 0.26 0.30 1.04 -0.01
9287 || orf19.6848 || VPS16 || || Protein similar to S. cerevisiae Vps16p, which is involved in protein-vacuolar targeting; likely to be essential for growth, based on insertional mutagenesis; downregulated in biofilm or in azole-resistant strain that overexpresses MDR1 || 1 0.17 0.12 -0.12 -0.39 0.59 0.22 0.08 0.05 0.04 -0.33 0.02 0.02 0.11 -0.10 0.71 0.03
9288 || orf19.2850 || || || Protein of unknown function; induced by nitric oxide independent of Yhb1p || 1 0.09 0.26 -0.21 -0.31 1.17 0.55 0.16 -0.06 -0.40 -0.20 0.43 -0.15 0.38 -0.45 1.35 0.27
9289 || orf19.5727 || || || Ortholog of C. dubliniensis CD36 : Cd36_64130, C. parapsilosis CDC317 : CPAR2_601230, Candida tenuis NRRL Y-1498 : CANTEDRAFT_115908 and Debaryomyces hansenii CBS767 : DEHA2E12540g || 1 0.11 0.03 0.15 -0.01 1.63 1.23 -0.16 0.06 -0.25 -0.52 0.13 0.14 -0.07 -0.26 1.44 -0.11
9290 || orf19.2968 || || || Protein of unknown function; Spider biofilm induced || 1 0.13 1.22 -0.65 -0.40 3.29 2.92 -0.04 -0.28 -0.13 -0.47 0.15 -0.45 0.57 -0.83 2.54 -1.16
9291 || orf19.4318 || MIG1 || || C2H2 transcription factor; repressor; regulates genes for carbon source utilization; Tup1-dependent and independent functions; hyphal, Hap43 and caspofungin repressed; Spider and flow model biofilm induced || 1 0.39 0.27 -0.81 -0.18 1.62 1.09 -0.13 -0.69 -1.59 -1.24 0.09 -0.60 0.50 -0.39 1.09 0.30
9292 || orf19.4318 || MIG1 || || C2H2 transcription factor; repressor; regulates genes for carbon source utilization; Tup1-dependent and independent functions; hyphal, Hap43 and caspofungin repressed; Spider and flow model biofilm induced || 1 -0.00 0.07 -0.47 -0.16 1.25 1.31 -0.35 -0.47 -1.23 -0.75 -0.10 -0.17 0.09 0.17 0.96 0.40
9293 || orf19.6408 || || || Putative DnaJ-like heat shock/chaperone; Hap43-repressed; Spider and F-12/CO2 biofilm induced || 1 -0.23 -0.11 0.08 -0.26 0.61 0.92 -0.40 -0.27 -0.64 -0.84 0.01 -0.40 0.09 -0.30 0.43 -0.18
9294 || orf19.6408 || || || Putative DnaJ-like heat shock/chaperone; Hap43-repressed; Spider and F-12/CO2 biofilm induced || 1 -0.12 -0.25 -0.02 -0.49 0.78 1.24 -0.36 -0.21 -0.57 -0.69 0.25 -0.28 0.06 0.22 0.70 -0.04
9295 || orf19.3826 || || || Predicted transmembrane protein with a role in cell wall polymer composition; Plc1-regulated; Spider biofilm induced || 1 -0.35 -0.42 -0.83 -0.75 1.08 1.32 0.53 -0.15 -0.17 -0.95 -0.14 -0.46 0.22 -0.01 1.10 -0.26
9296 || orf19.3742 || || || Protein of unknown function; Spider biofilm induced; upregulated in a cyr1 null mutant || 1 -0.32 0.01 -0.44 -0.78 1.43 1.29 0.20 -0.19 -0.41 -0.79 0.39 -0.49 0.16 -0.14 1.02 0.15
9297 || orf19.2968 || || || Protein of unknown function; Spider biofilm induced || 1 -0.33 -0.37 -1.02 -1.14 2.26 3.00 -0.47 -0.45 -0.98 -0.95 -0.48 -0.53 -0.10 -0.79 2.61 -0.40
9298 || orf19.2341 || HNT1 || || Protein with similarity to protein kinase C inhibitor-I; protein level decreases in stationary phase cultures || 1 -0.38 -0.34 0.00 -0.18 1.13 1.29 0.13 -0.43 -0.37 -0.87 -0.14 0.11 0.12 -0.62 1.31 -0.14
9299 || orf19.7028 || || || Predicted ORF in Assemblies 19, 20 and 21; merged with orf19.7027 in Assembly 21 || 1 -0.61 -0.67 -0.53 -0.73 2.85 2.81 0.01 -0.85 -0.43 -1.84 -0.57 -0.29 0.45 -1.72 1.55 0.31
9300 || orf19.7028 || || || Predicted ORF in Assemblies 19, 20 and 21; merged with orf19.7027 in Assembly 21 || 1 -1.20 -1.07 -1.15 -1.45 3.23 3.11 -0.13 -1.16 -0.63 -2.09 -0.72 -0.35 0.44 -2.08 1.84 0.23
9301 || orf19.5416 || ESA1 || || Subunit of the NuA4 histone acetyltransferase complex; member of MYST family; Spider biofilm induced || 1 -0.73 -0.44 -0.48 -0.67 1.48 1.30 -0.09 -0.54 -0.30 -0.57 -0.09 -0.13 -0.13 0.18 0.51 0.19
9302 || orf19.5530 || NAB3 || || Putative nuclear polyadenylated RNA-binding protein; flucytosine repressed || 1 -0.10 0.04 -0.23 -0.21 0.87 0.43 -0.02 -0.22 -0.12 -0.25 0.10 0.02 0.16 -0.23 0.29 -0.12
9303 || orf19.7595 || || || Has domain(s) with predicted dynactin complex localization || 1 0.42 0.32 -0.21 -0.54 1.05 1.23 -0.03 -0.37 -0.46 -0.25 0.28 -0.11 0.93 -0.01 0.22 0.35
9304 || orf19.3649 || || || Ortholog(s) have adenyl-nucleotide exchange factor activity, role in cytoplasm-associated proteasomal ubiquitin-dependent protein catabolic process, cytoplasmic translation and cytosolic ribosome, nucleus localization || 1 0.60 0.78 -0.43 -1.48 2.76 2.34 -0.21 -0.13 -0.85 -0.83 0.42 -0.36 0.97 0.09 0.84 0.12
9305 || orf19.3649 || || || Ortholog(s) have adenyl-nucleotide exchange factor activity, role in cytoplasm-associated proteasomal ubiquitin-dependent protein catabolic process, cytoplasmic translation and cytosolic ribosome, nucleus localization || 1 0.01 -0.06 -0.37 -1.20 1.94 1.95 -0.70 -0.50 -1.06 -1.12 -0.25 -0.20 0.36 -0.22 0.43 0.11
9306 || orf19.4407 || || || Protein of unknown function; Hap43-repressed gene || 1 0.08 0.01 -0.23 -0.49 1.07 1.10 -0.10 -0.32 -0.37 -0.96 -0.19 -0.22 0.46 0.04 0.40 0.53
9307 || orf19.4407 || || || Protein of unknown function; Hap43-repressed gene || 1 0.02 -0.05 -0.16 -0.65 1.00 1.09 -0.15 -0.34 -0.25 -0.84 -0.33 -0.08 0.17 -0.14 0.20 0.67
9308 || orf19.5068 || IRE1 || || Putative protein kinase; role in cell wall regulation; mutant is hypersensitive to caspofungin; Spider biofilm induced || 1 -0.15 -0.05 -0.37 -0.86 0.91 0.53 -0.24 -0.33 -0.12 -0.37 -0.12 0.33 -0.09 0.21 0.48 0.14
9309 || orf19.3192 || STI1 || || Protein that interacts with Cdc37 and Crk1 in two-hybrid; may be involved in Cdc37 chaperone activity; soluble protein in hyphae; protein in exponential and stationary phase yeast cultures; YNB biofilm induced; Spider biofilm induced || 1 0.03 -0.08 -0.85 -1.18 0.77 1.05 -0.08 -0.15 -0.56 -0.30 0.28 0.39 0.20 0.14 1.00 0.20
9310 || orf19.3368 || || || Ortholog of Candida albicans WO-1 : CAWG_03466 || 1 0.08 -0.16 -1.72 -1.77 1.25 1.83 0.13 -0.46 0.21 -0.25 0.01 1.47 -0.49
9311 || orf19.4965 || || || Protein of unknown function; rat catheter biofilm induced || 1 1.07 0.31 -0.67 -1.25 1.40 1.15 0.22 -0.52 -0.44 -0.38 -0.11 0.08 -0.22 0.22 1.25 -0.10
9312 || orf19.567 || TFB3 || || Putative C3HC4 zinc finger transcription factor; transcript positively regulated by Tbf1; Spider biofilm induced || 1 0.06 0.14 -0.43 -0.82 0.60 0.42 0.04 -0.18 -0.42 -0.12 0.47 0.09 0.31 -0.06 0.37 -0.01
9313 || orf19.5040 || || || Ortholog(s) have nucleocytoplasmic transporter activity, phospholipid binding, single-stranded DNA binding activity || 1 0.08 0.27 -0.50 -0.43 0.76 0.70 -0.06 -0.44 -0.38 0.02 0.16 0.47 0.39 -0.43 0.87 -0.05
9314 || orf19.5040 || || || Ortholog(s) have nucleocytoplasmic transporter activity, phospholipid binding, single-stranded DNA binding activity || 1 0.13 0.22 -0.25 -0.50 0.74 0.57 -0.10 -0.45 -0.40 0.00 0.25 0.39 0.27 -0.21 0.76 0.37
9315 || orf19.6491 || || || Ortholog of Candida albicans WO-1 : CAWG_05572 || 1 -0.32 0.11 -0.60 -0.63 0.89 1.54 -0.17 -0.92 -0.87 0.45 0.25 -0.02 0.22 1.08 0.42
9316 || orf19.2545 || DOT6 || || Protein with a predicted role in telomeric gene silencing and filamentation; repressed by high-level peroxide stress; Spider biofilm induced || 1 -0.02 -0.10 -0.15 -0.31 0.61 1.27 0.09 -0.64 -0.29 0.00 -0.04 0.07 0.31 -0.13 0.58 -0.07
9317 || orf19.4225 || LEU3 || || Zn(II)2Cys6 transcription factor; predicted regulator branched-c ofhain amino acid biosynthesis genes; alkaline induced; induced by Mnl1 under weak acid stress; required for yeast cell adherence to silicone substrate; Spider biofilm induced || 1 -0.43 -0.25 -0.18 -0.55 1.28 1.22 -0.79 -0.63 -0.42 -0.21 0.59 -0.06 -0.38 -0.58 0.60 0.13
9318 || orf19.243 || OXR1 || || Ortholog(s) have role in cellular response to oxidative stress and cytosol, mitochondrion, nucleus localization || 1 -0.25 -0.05 0.06 -0.28 0.68 1.13 -0.45 -0.33 -0.37 -0.60 0.35 0.53 -0.72 -0.31 0.37 0.22
9319 || orf19.5612 || BMT4 || || Beta-mannosyltransferase; for elongation of beta-mannose chains on the acid-labile fraction of cell wall phosphopeptidomannan; 9-gene family member; regulated by Tsa1, Tsa1B; flow model biofilm induced; rat catheter biofilm repressed || 1 -0.95 0.03 -0.22 -0.14 1.69 2.87 -0.79 -0.91 -0.55 -1.46 1.11 0.67 -1.44 -1.93 1.65 0.99
9320 || orf19.5612 || BMT4 || || Beta-mannosyltransferase; for elongation of beta-mannose chains on the acid-labile fraction of cell wall phosphopeptidomannan; 9-gene family member; regulated by Tsa1, Tsa1B; flow model biofilm induced; rat catheter biofilm repressed || 1 -0.52 -0.79 -0.37 -0.72 1.64 2.88 -0.62 -1.14 -1.01 -1.92 1.28 0.97 -0.97 -2.19 1.70 0.80
9321 || orf19.6474 || || || Protein with chitin synthesis regulation, resistance to Congo red domain; membrane-localized protein; Spider biofilm induced || 1 -0.14 -0.01 -0.32 -0.39 1.01 1.14 -0.34 -0.36 -0.33 -0.68 0.63 0.91 -0.72 -0.52 1.23 -0.06
9322 || orf19.2863 || || || Ortholog of C. dubliniensis CD36 : Cd36_28090, C. parapsilosis CDC317 : CPAR2_802560, Candida tenuis NRRL Y-1498 : CANTEDRAFT_104949 and Debaryomyces hansenii CBS767 : DEHA2A12848g || 1 -0.24 -0.24 -0.33 -0.31 0.83 1.07 -0.37 -0.00 -0.52 -0.69 0.68 0.48 -0.50 -0.76 1.22 0.39
9323 || orf19.2863 || || || Ortholog of C. dubliniensis CD36 : Cd36_28090, C. parapsilosis CDC317 : CPAR2_802560, Candida tenuis NRRL Y-1498 : CANTEDRAFT_104949 and Debaryomyces hansenii CBS767 : DEHA2A12848g || 1 -0.46 -0.33 -0.41 -0.73 0.83 1.10 -0.57 -0.13 -0.61 -0.38 0.86 0.72 -0.62 -0.42 1.28 0.74
9324 || orf19.2172 || ARA1 || || D-Arabinose dehydrogenase; dehydro-D-arabinono-1,4-lactone synthesis; active on D-arabinose, L-fucose, L-xylose, L-galactose; inhibited by metal ions, thiol group-specific reagents; induced on polystyrene adherence; Spider biofilm induced || 1 -0.28 -0.22 -0.15 -0.22 0.41 1.10 -0.35 -0.44 -0.37 -1.14 0.93 1.25 -0.28 -0.77 1.06 0.57
9325 || orf19.7214 || || || Glucan 1,3-beta-glucosidase; regulated by Nrg1, Tup1 and possibly Tac1; induced by NO and during cell wall regeneration; stationary phase enriched; possibly essential (UAU1 method); F-12/CO2 early biofilm induced; flow biofilm repressed || 1 0.02 0.07 0.12 0.18 0.80 1.18 -0.77 -0.75 -0.28 -1.05 0.60 0.93 -0.06 -0.83 1.12 0.35
9326 || orf19.4203 || || || Ortholog(s) have role in nuclear pore organization, spindle pole body duplication and nuclear pore transmembrane ring, spindle pole body localization || 1 -0.10 -0.25 0.12 -0.15 0.31 0.61 -0.14 -0.14 -0.16 -0.29 0.17 0.19 0.03 -0.12 0.41 0.10
9327 || orf19.1246 || || || Putative eisosome component role in proper eisosome assembly; upregulated in cyr1 null mutant || 1 -0.18 -0.44 -0.14 -0.11 0.46 0.85 -0.03 -0.01 -0.31 -0.67 0.32 0.45 0.07 -0.64 0.89 0.27
9328 || orf19.1246 || || || Putative eisosome component role in proper eisosome assembly; upregulated in cyr1 null mutant || 1 -0.29 -0.30 -0.08 -0.21 0.83 0.98 -0.02 -0.10 -0.43 -0.68 0.51 0.56 0.17 -0.37 1.20 0.76
9329 || orf19.2531 || CSP37 || || Hyphal cell wall protein; role in progression of mouse systemic infection; predicted P-loop, divalent cation binding, N-glycosylation sites; expressed in yeast and hyphae; hyphal downregulated; stationary-phase enriched; GlcNAc-induced || 1 -0.05 -0.05 -0.54 -0.97 1.37 1.24 -0.86 -1.01 -1.40 -2.30 0.89 0.88 0.01 -0.91 2.31 0.15
9330 || orf19.2531 || CSP37 || || Hyphal cell wall protein; role in progression of mouse systemic infection; predicted P-loop, divalent cation binding, N-glycosylation sites; expressed in yeast and hyphae; hyphal downregulated; stationary-phase enriched; GlcNAc-induced || 1 -0.03 -0.06 -0.33 -0.48 1.49 1.60 -0.85 -0.79 -1.07 -1.93 0.85 0.17 -0.01 -0.61 2.29 0.24
9331 || orf19.147 || YAK1 || || Predicted serine-threonine protein kinase; involved in hyphal growth regulation and biofilm formation; flow model biofilm induced; induced in core caspofungin response || 1 -0.48 -0.44 -0.24 -0.37 0.99 0.84 -0.76 -0.71 -0.62 -0.85 0.08 -0.01 -0.27 -0.15 1.14 0.55
9332 || orf19.1240 || || || Ortholog of S. cerevisiae : YPR117W, C. glabrata CBS138 : CAGL0D04510g, C. dubliniensis CD36 : Cd36_45200, C. parapsilosis CDC317 : CPAR2_500480 and Candida tenuis NRRL Y-1498 : CANTEDRAFT_120679 || 1 -0.46 -0.62 -0.33 -0.42 0.81 0.63 -0.38 -0.34 -0.69 -0.74 0.12 0.13 0.19 -0.22 1.16 0.42
9333 || orf19.7344 || || || Ortholog(s) have DNA binding, chromatin binding, histone deacetylase activity || 1 -0.40 -0.39 -0.97 -0.56 1.15 0.86 -0.37 -0.45 -0.74 -0.55 0.30 0.17 0.26 -0.51 1.76 0.24
9334 || orf19.7344 || || || Ortholog(s) have DNA binding, chromatin binding, histone deacetylase activity || 1 -0.32 -0.54 -0.89 -0.70 1.01 0.75 -0.25 -0.86 -0.75 -0.79 0.31 0.09 0.25 -0.77 1.67 0.26
9335 || orf19.4998 || ROB1 || || Zn(II)2Cys6 transcription factor; required for Spider model biofilm formation; mutant displays abnormal colony morphology and invasive growth; caspofungin repressed; flow model biofilm induced; rat catheter biofilm repressed || 1 -0.67 -0.58 -1.61 -1.71 1.86 1.62 -0.82 -0.93 -0.71 -1.16 0.40 0.65 -1.51 -1.65 1.57 0.98
9336 || orf19.4998 || ROB1 || || Zn(II)2Cys6 transcription factor; required for Spider model biofilm formation; mutant displays abnormal colony morphology and invasive growth; caspofungin repressed; flow model biofilm induced; rat catheter biofilm repressed || 1 -0.26 -0.20 -1.65 -1.66 2.82 2.21 -0.84 -0.83 -0.83 -1.24 0.91 0.92 -1.48 -1.77 2.34 1.11
9337 || orf19.5727 || || || Ortholog of C. dubliniensis CD36 : Cd36_64130, C. parapsilosis CDC317 : CPAR2_601230, Candida tenuis NRRL Y-1498 : CANTEDRAFT_115908 and Debaryomyces hansenii CBS767 : DEHA2E12540g || 1 -0.15 -0.29 -0.63 -0.65 1.13 0.80 -0.51 -0.52 -0.39 -0.27 0.03 -0.13 -0.31 -0.67 1.14 0.35
9338 || orf19.5727 || || || Ortholog of C. dubliniensis CD36 : Cd36_64130, C. parapsilosis CDC317 : CPAR2_601230, Candida tenuis NRRL Y-1498 : CANTEDRAFT_115908 and Debaryomyces hansenii CBS767 : DEHA2E12540g || 1 -0.59 -0.38 -0.77 -0.74 1.23 1.01 -0.70 -0.48 -0.12 -0.15 0.02 -0.03 -0.30 -0.31 1.09
9339 || orf19.2050 || || || Ortholog(s) have sterol esterase activity, role in cellular lipid metabolic process, sterol metabolic process and fungal-type vacuole, integral to membrane, lipid particle localization || 1 -0.75 -0.87 -0.58 -0.74 1.55 1.55 -0.75 -0.49 -0.38 -0.74 0.12 0.19 -0.41 -0.21 1.33 0.73
9340 || orf19.220 || PIR1 || || 1,3-beta-glucan-linked cell wall protein; N-mannosylated, O-glycosylated by Pmt1; cell wall defect in het mutant; Hog1/fluconazole/hypoxia induced; iron/Efg1/Plc1/temp regulated; flow model biofilm induced; hyphal, Spider biofilm repressed || 1 -0.83 -1.00 -0.76 -0.44 1.31 1.32 -0.35 -0.38 0.18 -0.89 0.39 0.63 -0.24 -0.28 1.92 0.59
9341 || orf19.2892 || || || Ortholog of C. dubliniensis CD36 : Cd36_45910, C. parapsilosis CDC317 : CPAR2_501110, Candida tenuis NRRL Y-1498 : CANTEDRAFT_119393 and Debaryomyces hansenii CBS767 : DEHA2E08976g || 1 -0.85 -0.63 -0.75 -0.64 0.93 1.14 -0.15 -0.14 -0.27 -0.42 0.26 0.36 -0.18 -0.52 1.14 0.27
9342 || orf19.3861 || SIS1 || || Putative Type II HSP40 co-chaperone; macrophage/pseudohyphal-repressed; heavy metal (cadmium) stress-induced; heterozygous null mutant displays sensitivity to virgineone; rat catheter biofilm induced || 1 -0.44 -0.46 -0.99 -1.34 1.68 1.49 -0.32 0.04 -0.53 -0.37 0.75 0.68 -0.41 0.05 1.54 0.57
9343 || orf19.3861 || SIS1 || || Putative Type II HSP40 co-chaperone; macrophage/pseudohyphal-repressed; heavy metal (cadmium) stress-induced; heterozygous null mutant displays sensitivity to virgineone; rat catheter biofilm induced || 1 -0.47 -0.55 -0.68 -1.21 1.44 1.33 -0.29 -0.11 -0.34 -0.34 0.51 0.50 -0.41 -0.02 1.20 0.03
9344 || orf19.2268 || RCK2 || || Predicted MAP kinase-activated protein kinase, similar to S. cerevisiae serine/threonine protein kinase Rck2p; induced by osmotic stress via Hog1p; macrophage/pseudohyphal-repressed; mutants are sensitive to rapamycin || 1 -0.22 -0.30 -0.50 -0.76 1.01 1.39 -0.26 -0.48 -0.40 -0.26 0.31 0.52 -0.51 0.01 1.22 0.13
9345 || orf19.7140 || || || Putative catechol o-methyltransferase; stationary phase enriched protein; transcription upregulated in clinical isolates from HIV+ patients with oral candidiasis; Spider biofilm repressed || 1 -0.43 -0.50 -0.51 -0.72 0.80 1.16 -0.29 -0.46 -0.22 -0.63 0.27 0.54 -0.31 0.31 1.07 0.29
9346 || orf19.5569 || || || Ortholog(s) have role in maintenance of rDNA, mitotic sister chromatid segregation and nuclear envelope localization || 1 -0.18 -0.18 -0.34 -0.50 1.02 0.74 -0.32 -0.48 -0.62 -0.10 0.65 0.64 -0.13 -0.03 1.20 0.82
9347 || orf19.5569 || || || Ortholog(s) have role in maintenance of rDNA, mitotic sister chromatid segregation and nuclear envelope localization || 1 -0.08 -0.13 -0.38 -0.63 1.04 0.54 -0.31 -0.59 -0.55 -0.14 0.60 0.59 -0.12 -0.60 1.11 0.92
9348 || orf19.1535 || || || Protein of unknown function; Hap43-induced gene || 1 0.03 -0.10 -0.28 -0.22 0.42 0.41 -0.42 -0.14 -0.18 -0.12 0.30 0.24 -0.33 -0.09 0.35 0.37
9349 || orf19.3862 || || || Putative intracellular transport protein; heterozygous null mutant displays sensitivity to rapamycin; expression upregulated during growth in the mouse cecum || 1 0.13 0.06 -0.03 -0.28 0.69 0.44 0.02 0.10 -0.20 -0.18 0.15 0.05 -0.40 0.31 0.58 0.28
9350 || orf19.2095 || || || Ortholog(s) have role in negative regulation of transcription from RNA polymerase II promoter in response to iron and cytosol, nucleus localization || 1 0.14 0.12 -0.06 -0.13 0.82 0.54 -0.31 -0.34 -0.05 0.12 0.46 0.35 -0.47 -0.23 0.48 0.39
9351 || orf19.6498 || || || Ortholog(s) have role in RNA polymerase II complex localization to nucleus, RNA polymerase III complex localization to nucleus and DNA-directed RNA polymerase II, holoenzyme, cytoplasm localization || 1 0.05 0.42 -0.04 0.14 1.07 0.77 -0.04 -0.01 -0.19 -0.32 0.80 0.07 -0.77 -0.14 0.88 0.46
9352 || orf19.5833 || || || Ortholog(s) have polyubiquitin binding activity || 1 0.15 0.20 -0.16 -0.10 0.66 0.67 -0.08 -0.03 -0.24 -0.01 0.36 0.38 -0.42 -0.08 0.84 0.36
9353 || orf19.5833 || || || Ortholog(s) have polyubiquitin binding activity || 1 0.38 0.43 -0.25 -0.17 1.01 0.59 -0.05 -0.08 -0.28 0.03 0.37 0.32 -0.29 0.07 1.13 0.32
9354 || orf19.900 || NSP1 || || Essential component of the nuclear pore complex; sumoylation target; stationary phase enriched protein; rat catheter biofilm repressed || 1 0.10 0.11 -0.19 -0.30 0.84 0.75 -0.18 0.01 -0.35 -0.09 -0.01 0.28 -0.38 -0.37 0.67 0.16
9355 || orf19.5833 || || || Ortholog(s) have polyubiquitin binding activity || 1 0.19 0.20 -0.37 -0.37 0.76 0.49 -0.20 -0.19 -0.54 -0.01 0.17 -0.23 -0.50 -0.50 0.90 0.21
9356 || orf19.2190 || VRP1 || || Verprolin-related protein involved in actin cytoskeleton organization and polarized morphogenesis; interacts with Wal1p and Myo5p; downregulated upon adherence to polystyrene || 1 -0.10 -0.04 -0.28 -0.36 0.75 0.31 0.19 0.15 -0.36 -0.28 0.36 0.28 -0.10 -0.42 0.65 0.07
9357 || orf19.6059 || TTR1 || || Putative glutaredoxin; described as a glutathione reductase; induced by human neutrophils and benomyl treatment; alkaline repressed; regulated by Gcn2 and Gcn4; required for virulence in mouse model; Spider biofilm induced || 1 0.04 0.20 -0.70 -0.60 1.52 1.32 0.66 0.29 -0.76 -0.86 1.71 0.79 -0.75 -0.35 2.17 0.52
9358 || orf19.6059 || TTR1 || || Putative glutaredoxin; described as a glutathione reductase; induced by human neutrophils and benomyl treatment; alkaline repressed; regulated by Gcn2 and Gcn4; required for virulence in mouse model; Spider biofilm induced || 1 0.10 0.19 -0.52 -0.25 1.41 1.38 0.61 0.28 -0.55 -0.87 1.64 0.73 -0.37 -0.73 1.95 0.39
9359 || orf19.335 || || || Sef1p-, Sfu1p-, and Hap43p-regulated gene || 1 0.28 0.42 -0.42 -0.13 1.29 0.66 -0.50 -0.23 -0.12 -1.06 0.72 0.26 -0.10 -0.30 1.08 0.20
9360 || orf19.3153 || MSS4 || || Phosphatidylinositol-4-phosphate 5-kinase; activity induced by phosphatidic acid (Pld1 product); macrophage/pseudohyphal-repressed; mRNA binds to She3, localized to yeast cell buds and hyphal tips; Hap43-induced; Spider biofilm induced || 1 -0.44 -0.59 -0.26 -0.58 1.00 0.82 0.08 -0.53 -0.14 -0.26 0.73 0.32 0.28 -0.16 0.70 0.21
9361 || orf19.6827 || SLU7 || || Protein similar to S. cerevisiae RNA splicing factor, Slu7; induced by alpha pheromone in SpiderM medium || 1 -0.88 -0.87 -0.26 -0.31 0.95 1.58 -0.20 -0.09 0.27 0.32 0.45 1.04 0.17 0.49 0.56 0.99
9362 || orf19.4913 || || || Ortholog(s) have ubiquitin binding activity, role in cellular protein localization, positive regulation of deubiquitinase activity and cell cortex of cell tip, cell division site, cytosol localization || 1 -0.29 -0.16 0.23 -0.40 0.75 0.86 -0.12 0.10 -0.03 -0.32 0.57 0.65 0.17 0.51 1.11 0.88
9363 || orf19.2084 || CDH1 || || Protein involved in regulation of mitosis; similar to S. cerevisiae Cdh1, which is an APC/C component; transcriptionally induced by Mnl1 under weak acid stress || 1 -0.17 -0.19 0.12 -0.16 0.35 0.45 0.05 0.12 0.08 0.01 0.09 0.30 0.08 0.40 0.45 0.33
9364 || orf19.3701 || || || Protein of unknown function; mutants are viable; ortholog of S. cervisiae Art10, a protein of unknown function || 1 -0.33 -0.32 0.07 -0.70 0.58 1.39 0.12 -0.06 0.36 -0.09 0.05 0.46 0.29 0.48 1.02 0.74
9365 || orf19.1576 || || || Ortholog(s) have nuclear localization sequence binding, ubiquitin binding activity, role in response to ethanol and cytosol localization || 1 0.04 -0.06 -0.11 -0.09 0.63 0.82 -0.06 -0.16 0.09 0.01 0.00 0.34 0.18 0.25 0.71 0.39
9366 || orf19.7483 || CRM1 || || Functional homolog of S. cerevisiae Crm1, which acts in protein nuclear export; predicted to be resistant to antifungal drug leptomycin B; partially suppresses signal transduction defects of S. cerevisiae ste20 mutant || 1 0.00 -0.05 -0.16 -0.29 0.64 0.58 -0.31 -0.21 -0.01 -0.17 0.15 0.32 -0.10 0.35 0.78 0.36
9367 || orf19.7397 || || || Ortholog(s) have sequence-specific DNA binding activity and cytoplasm, nucleus, spindle localization || 1 -0.21 -0.29 -0.49 -0.45 0.66 0.87 -0.20 -0.31 0.04 0.06 -0.11 0.46 0.05 0.27 0.62 0.24
9368 || orf19.2368 || || || Predicted component of U5 snRNP; Spider biofilm induced || 1 -0.22 0.03 -0.42 -0.61 0.67 0.97 -0.25 -0.28 0.24 0.12 0.27 0.60 -0.01 0.25 0.44 0.30
9369 || orf19.1954 || PUS4 || || Putative pseudouridine synthase; transcript regulated by Nrg1, Mig1, and Tup1 || 1 -0.14 -0.28 -0.14 -1.00 1.60 1.42 -0.26 -0.07 -0.15 0.33 0.81 0.48 0.22 0.46 1.08 0.23
9370 || orf19.4658 || || || RING finger and CHY zinc finger domain-containing protein; mutant are viable || 1 -0.08 0.04 -0.20 -0.57 1.43 1.11 -0.33 -0.14 -0.01 -0.12 0.34 0.00 0.13 0.16 0.55 0.41
9371 || orf19.5875 || VAM3 || || Predicted target membrane receptor (t-SNARE) involved in vacuolar transport, endocytosis, and secretion; required for biofilm formation in RPMI-1640 and for virulence; rat catheter biofilm repressed || 1 -0.41 -0.09 -0.09 -0.32 1.69 1.21 -0.37 -0.51 -0.01 -0.14 0.09 0.41 0.12 0.06 0.78 0.43
9372 || orf19.254 || || || Protein of unknown function; Hog1p-repressed; Spider biofilm induced || 1 -1.05 -0.98 -0.09 -0.39 1.79 1.45 -0.65 -0.44 -0.19 -0.21 -0.17 0.52 0.26 0.36 1.42 0.27
9373 || orf19.6382 || || || Putative MRP/CFTR-subfamily ABC transporter; member of multidrug resistance-associated protein (MRP) subfamily of ABC family; similar to S. cerevisiae Bpt1p || 1 -0.31 -0.49 0.05 -0.24 0.72 0.61 -0.16 -0.24 0.17 -0.01 -0.01 0.43 -0.25 -0.04 0.63 0.26
9374 || orf19.3298 || CCH1 || || Voltage-gated Ca2+ channel of the high affinity calcium uptake system; roles in thigmotropism, establishment of galvanotropism; transcript regulated by Nrg1 and Mig1; flow model biofilm repressed || 1 -0.22 -0.27 -0.13 -0.42 0.50 0.34 0.02 -0.25 0.12 -0.14 -0.01 0.25 0.01 0.33 0.44 0.38
9375 || orf19.2458 || SIP5 || || Protein of unknown function; flow model, rat catheter and Spider biofilm induced || 1 -0.49 -0.86 -0.91 -1.32 1.04 0.91 -0.04 -0.61 0.31 -0.52 0.34 0.88 0.28 0.35 2.20 1.07
9376 || orf19.2458 || SIP5 || || Protein of unknown function; flow model, rat catheter and Spider biofilm induced || 1 -0.88 -0.98 -1.08 -1.34 1.07 1.68 0.09 -0.51 0.12 -0.31 0.49 0.88 0.75 0.44 2.16 0.77
9377 || orf19.2748 || ARG83 || || GAL4-like Zn(II)2Cys6 transcription factor; clade-associated expression; null shows abnormal regulation of invasive colony growth, is unable to utilize proline as a nitrogen source; flow model biofilm induced || 1 -0.10 -0.19 -0.19 -0.31 1.10 0.63 -0.06 -0.14 0.19 -0.00 -0.34 0.72 -0.01 0.05 0.69 0.47
9378 || orf19.1290 || XKS1 || || Putative xylulokinase; Hap43-repressed; induced by prostaglandins; rat catheter biofilm repressed || 1 -0.03 0.31 -0.02 -0.43 0.59 0.74 0.12 0.04 0.38 -0.93 0.12 0.57 0.16 -0.13 0.39 0.69
9379 || orf19.951 || || || Protein of unknown function; transcript repressed upon yeast-hyphal switch; fluconazole-induced; Hap43-repressed; flow model biofilm induced || 1 -0.03 0.16 0.00 -0.32 0.85 1.11 -0.54 -0.58 -0.01 -0.86 -0.31 -0.02 0.47 0.05 0.33 0.80
9380 || orf19.4752 || MSN4 || || Zinc finger transcription factor; similar to S. cerevisiae Msn4, but not a significant stress response regulator in C. albicans; partly complements STRE-activation defect of S. cerevisiae msn2 msn4 double mutant; flow model biofilm induced || 1 -0.22 -0.16 -0.25 -0.65 0.99 1.53 -0.60 -0.87 -0.10 -1.00 -0.24 0.46 0.61 -0.13 0.77 1.00
9381 || orf19.4535 || PTR3 || || Protein similar to S. cerevisiae Ptr3p, which is a sensor of external amino acids; expression upregulated in an ssr1 null mutant || 1 0.08 -0.19 0.03 -0.38 0.61 0.80 -0.04 -0.32 0.27 -0.58 0.05 0.45 0.13 -0.26 0.26 0.41
9382 || orf19.2063 || || || Ortholog of C. parapsilosis CDC317 : CPAR2_213140, C. dubliniensis CD36 : Cd36_15600, Lodderomyces elongisporus NRLL YB-4239 : LELG_01226 and Debaryomyces hansenii CBS767 : DEHA2B02442g || 1 -0.11 -0.33 0.06 -0.40 0.92 1.65 -0.54 -0.23 -0.60 -1.03 0.02 1.12 -0.02 -0.37 0.65 1.28
9383 || orf19.1664 || || || Protein of unknown function; expression downregulated in an ssr1 null mutant || 1 -0.12 -0.12 -0.21 -0.30 0.83 1.01 -0.60 -0.41 -0.12 -0.97 0.20 0.40 -0.20 -0.21 0.18 0.86
9384 || orf19.2839 || CIRT4B || || Cirt family transposase; transcript repressed in an azole-resistant strain that overexpresses CDR1 and CDR2; Hap43-repressed; flow model biofilm induced || 1 -0.70 -0.63 -0.48 -1.17 0.96 1.72 -0.55 -0.57 -0.40 -2.00 0.34 0.65 0.26 -0.46 0.75 1.33
9385 || orf19.2839 || CIRT4B || || Cirt family transposase; transcript repressed in an azole-resistant strain that overexpresses CDR1 and CDR2; Hap43-repressed; flow model biofilm induced || 1 -0.25 -0.21 -0.35 -0.59 1.12 1.76 -0.31 -0.22 -0.25 -1.82 0.81 0.70 0.31 -0.54 1.18 1.37
9386 || orf19.5131 || || || Ortholog of S. cerevisiae Gid7, a GID complex protein; involved in proteasome-dependent catabolite inactivation of fructose-1,6-bisphosphatase; Hap43-repressed gene || 1 -0.25 -0.32 -0.11 -0.48 0.65 0.53 -0.29 -0.24 0.14 -0.75 0.32 0.63 -0.00 -0.05 0.50 0.53
9387 || orf19.5131 || || || Ortholog of S. cerevisiae Gid7, a GID complex protein; involved in proteasome-dependent catabolite inactivation of fructose-1,6-bisphosphatase; Hap43-repressed gene || 1 -0.25 -0.09 0.17 -0.37 0.53 0.65 -0.33 -0.40 0.29 -0.75 0.20 0.63 -0.02 0.06 0.39 0.68
9388 || orf19.5651 || || || Ortholog(s) have histone demethylase activity (H3-dimethyl-K4 specific), histone demethylase activity (H3-trimethyl-K4 specific) activity || 1 -0.53 -0.33 0.28 -0.42 0.89 1.11 -0.12 -0.77 -0.09 -0.67 0.53 1.05 0.15 0.14 1.00 1.27
9389 || orf19.4764 || || || Ortholog(s) have poly(A)-specific ribonuclease activity, role in mRNA 3'-end processing, postreplication repair and PAN complex localization || 1 0.07 -0.07 -0.14 -0.12 0.59 0.64 -0.21 -0.22 -0.53 -0.46 0.12 0.51 0.11 0.18 0.51 0.69
9390 || orf19.5676 || || || Ortholog(s) have cytosol, nucleus localization || 1 -0.07 -0.13 -0.34 -0.08 0.30 0.41 0.03 -0.09 -0.24 -0.37 0.11 0.30 0.09 -0.01 0.26 0.61
9391 || orf19.1604 || || || Predicted Gal4-like DNA-binding transcription factor; Spider biofilm induced || 1 -0.25 0.04 -0.28 -0.74 0.50 1.21 -0.38 -0.78 -0.71 -1.11 0.77 1.42 0.07 -0.47 0.15 1.50
9392 || orf19.5767 || || || Ortholog(s) have RNA binding activity and role in mRNA splicing, via spliceosome || 1 0.17 0.24 0.00 -0.44 0.93 1.01 -0.01 -0.39 -0.32 -0.41 0.56 0.27 -0.18 0.31 0.40 0.43
9393 || orf19.4728 || || || Ortholog(s) have role in histone deacetylation, negative regulation of meiosis and Set3 complex localization || 1 0.15 -0.04 -0.04 -0.22 0.72 0.44 -0.26 -0.20 0.11 -0.23 0.07 0.28 0.24 -0.03 0.26 0.08
9394 || orf19.928 || || || Ortholog of C. dubliniensis CD36 : Cd36_50610, C. parapsilosis CDC317 : CPAR2_303690, Candida tenuis NRRL Y-1498 : CANTEDRAFT_93989 and Debaryomyces hansenii CBS767 : DEHA2E15400g || 1 0.09 0.63 -0.47 -0.38 1.57 1.28 -0.78 -0.91 -0.09 -0.36 -0.57 0.74 0.31 -0.06 0.18 0.60
9395 || orf19.2926 || || || Putative nuclease required for DNA single- and double-strand break repair; rat catheter biofilm induced || 1 -0.07 0.37 -0.61 -0.19 0.88 0.72 -0.37 -0.44 -0.02 -0.39 0.34 0.49 -0.08 0.15 0.33 0.62
9396 || orf19.1958 || || || Dubious open reading frame || 1 0.45 0.26 -1.27 -0.48 1.07 1.08 -0.61 -0.57 -0.27 -0.56 -0.12 -0.19 -0.02 0.09 0.50 0.22
9397 || orf19.5413 || || || Ortholog(s) have role in mRNA splicing, via spliceosome and Prp19 complex, spliceosomal complex localization || 1 -0.29 -0.15 -0.81 -0.03 0.76 0.85 -0.46 -0.69 0.05 -0.28 -0.37 -0.01 -0.10 -0.06 0.32 -0.15
9398 || orf19.5864 || URK1 || || Protein similar to uridine kinase; repressed by ciclopirox olamine; Spider biofilm induced || 1 0.30 0.01 0.01 -0.49 0.58 0.58 -0.17 -0.84 -0.52 -0.34 0.13 0.01 0.10 -0.34 0.20 0.47
9399 || orf19.2839 || CIRT4B || || Cirt family transposase; transcript repressed in an azole-resistant strain that overexpresses CDR1 and CDR2; Hap43-repressed; flow model biofilm induced || 1 0.18 0.19 -0.96 -1.57 1.22 1.35 -0.58 -1.04 -1.08 -1.67 0.22 0.29 1.31 -0.56 0.25 1.42
9400 || orf19.3793 || || || Protein of unknown function; mRNA binds She3; regulated by Nrg1; upregulated in a cyr1 or ras1 mutant || 1 0.30 0.55 -0.50 -0.68 0.88 0.71 -0.85 -1.47 -1.58 -1.99 0.47 0.63 0.99 -0.84 0.50 -0.01
9401 || orf19.3793 || || || Protein of unknown function; mRNA binds She3; regulated by Nrg1; upregulated in a cyr1 or ras1 mutant || 1 0.34 0.27 -0.46 -0.50 0.46 0.60 -0.87 -1.37 -1.55 -1.59 0.47 0.77 0.77 -0.61 0.51 -0.08
9402 || orf19.307 || || || Ortholog(s) have transcription coactivator activity, role in histone acetylation, transcription from RNA polymerase II promoter and Ada2/Gcn5/Ada3 transcription activator complex, SAGA complex, SLIK (SAGA-like) complex localization || 1 -0.12 -0.21 -0.37 -0.30 0.56 -0.08 -0.29 -0.56 -0.37 -0.43 0.07 0.09 0.63 -0.33 0.18 0.49
9403 || orf19.6373 || DCP2 || || Ortholog(s) have m7G(5')pppN diphosphatase activity, mRNA binding activity and role in deadenylation-dependent decapping of nuclear-transcribed mRNA, deadenylation-independent decapping of nuclear-transcribed mRNA, stress granule assembly || 1 0.04 0.01 -0.10 -0.23 0.21 -0.04 -0.08 -0.20 -0.14 -0.50 0.09 0.28 0.17 -0.48 0.31 0.18
9404 || orf19.6832 || || || Protein of unknown function; regulated by Sef1p-, Sfu1p-, and Hap43p || 1 0.10 0.15 -0.39 -0.48 0.46 0.23 0.09 0.00 -0.16 -0.93 0.64 0.43 0.71 -0.36 0.38 0.31
9405 || orf19.738 || MYO5 || || Class I myosin; nonessential; role in cortical actin patch polarity and polar budding; required for hyphal growth, white-opaque switch; regulatory phosphorylation on S366; downregulated on adherence to polystyrene || 1 0.29 0.28 -0.66 -0.70 0.20 -0.08 0.38 0.11 -0.19 -0.55 0.22 -0.18 0.34 0.16 0.58 0.38
9406 || orf19.75 || || || Predicted exocyst component; ortholog of S. cerevisiae Sec5p; merged with orf19.74 in Assembly 21 || 1 0.35 0.25 -0.63 -0.79 0.57 -0.15 -0.11 -0.39 -0.19 -0.57 0.05 -0.20 0.19 -0.27 0.49 -0.03
9407 || orf19.173 || || || C2H2 transcription factor; induced by Mnl1 under weak acid stress || 1 0.15 0.27 -0.59 -0.91 1.03 0.09 -0.17 -0.23 -0.43 -0.89 0.60 -0.42 0.96 -0.08 1.03 0.02
9408 || orf19.1712 || GEA2 || || Putative ARF GTP/GDP exchange factor; induced in low iron; flow model biofilm repressed || 1 0.05 0.29 -0.32 -0.25 0.48 -0.03 0.19 -0.18 -0.41 -0.28 0.35 0.17 0.31 -0.15 0.53 0.08
9409 || orf19.1927 || SNM1 || || Protein similar to RNase MRP RNA binding protein; ciclopirox olamine induced; regulated by Sef1, Sfu1, and Hap43; Spider biofilm induced || 1 0.41 0.46 -0.38 -0.54 0.86 0.66 0.35 -0.17 -0.95 -0.33 -0.32 -0.15 0.69 0.02 0.68 0.03
9410 || orf19.3815 || || || Has domain(s) with predicted ubiquitin thiolesterase activity and role in ubiquitin-dependent protein catabolic process || 1 0.11 0.02 -0.20 -0.29 0.54 0.34 0.10 -0.32 -0.13 -0.52 0.13 -0.03 -0.15 0.23 0.12 -0.00
9411 || orf19.7444 || || || Ortholog(s) have cytoplasm, holo TFIIH complex localization || 1 0.14 0.15 -0.51 -0.39 0.64 0.39 0.46 0.26 -0.69 -0.72 0.69 0.04 -0.26 0.23 0.44 0.48
9412 || orf19.2505 || || || Ortholog of Candida albicans WO-1 : CAWG_02437 || 1 0.27 0.00 -0.17 1.54 0.69 -0.27 -0.86 -0.09 1.38 -0.44 0.46 0.59 1.38
9413 || orf19.4310 || || || Dubious open reading frame || 1 0.11 -0.15 -0.39 0.10 0.82 0.59 -0.26 0.17 0.33 -0.37 1.22 0.31 -0.13 0.41 0.91
9414 || orf19.3995 || RIM13 || || Protease of the pH response pathway; likely to mediate activation of Rim101 via C-terminal cleavage; required for alkaline pH-induced hyphal growth and for normal chlamydospore formation; Hap43-repressed; flow model biofilm induced || 1 0.26 0.18 0.14 -0.35 0.52 0.10 0.29 0.33 0.13 -0.54 0.42 0.30 0.25 -0.32 0.11 0.54
9415 || orf19.2290 || TOR1 || || Protein similar to TOR family phosphatidylinositol kinases; mutation confers resistance to rapamycin; involved in regulation of ribosome biogenesis, starvation response, and adhesion || 1 0.24 0.07 0.10 0.08 0.77 0.19 0.09 0.21 -0.01 -0.51 0.32 -0.01 0.06 -0.31 0.25 0.42
9416 || orf19.992 || LKH1 || || Putative leukotriene A(4) hydrolase; repressed during the mating process; Hog1p-induced || 1 -0.07 0.08 0.19 0.17 0.44 0.43 0.15 0.01 0.25 -0.34 0.09 0.14 -0.21 -0.16 -0.22 0.35
9417 || orf19.6898 || || || Protein similar to S. pombe SPBC1709.16c a predicted aromatic ring-opening dioxygenase; induced by benomyl treatment or in azole-resistant strain that overexpresses MDR1; Spider biofilm induced || 1 0.04 -0.06 0.36 0.59 0.74 0.83 0.07 -0.07 0.19 -1.15 1.10 0.92 -0.47 -1.09 0.07 1.14
9418 || orf19.2046 || POT1-2 || || Putative peroxisomal 3-ketoacyl CoA thiolase; Hap43-repressed || 1 -0.25 -0.14 0.06 0.04 0.05 0.24 -0.01 0.07 0.07 -0.64 0.32 -0.09 -0.35 -0.21 -0.12 0.52
9419 || orf19.6660 || || || Protein of unknown function; mRNA binds to She3; Hap43-repressed; rat catheter and flow model biofilm induced || 1 -0.21 -0.13 -0.21 0.24 0.54 1.21 0.34 0.31 -0.58 -0.99 1.31 0.03 -0.14 -0.17 0.35 1.39
9420 || orf19.4911 || || || BED zinc finger protein; predicted DNA binding protein; Spider biofilm repressed || 1 -0.28 -0.61 0.32 -0.04 0.03 0.39 -0.17 0.09 -0.49 -1.32 1.13 0.13 0.12 -0.31 0.60 0.83
9421 || orf19.131 || || || Ortholog of C. dubliniensis CD36 : Cd36_61330, C. parapsilosis CDC317 : CPAR2_602800, Candida tenuis NRRL Y-1498 : CANTEDRAFT_94450 and Debaryomyces hansenii CBS767 : DEHA2F15554g || 1 0.02 -0.12 -0.34 -0.38 0.74 0.05 0.09 -0.02 -0.56 -0.48 0.23 0.04 -0.28 -0.27 0.08 0.12
9422 || orf19.4003 || TIP20 || || Protein interacting with Sec20p, possibly involved in retrograde transport between the Golgi and the endoplasmic reticulum; similar to S. cerevisiae Tip20p || 1 -0.14 -0.22 -0.53 -0.87 0.43 -0.14 -0.06 0.11 -0.43 -0.31 0.06 0.07 -0.51 -0.27 0.31 -0.10
9423 || orf19.7602 || AHA1 || || Putative Hsp90p co-chaperone; Hap43-repressed; heavy metal (cadmium) stress-induced; oxidative stress-induced via Cap1; rat catheter biofilm induced; flow model biofilm repressed || 1 -0.12 -0.27 -0.52 -1.00 0.44 0.85 -0.05 0.31 -0.25 -0.23 0.42 0.26 -0.65 -0.02 0.11 -0.05
9424 || orf19.2555 || URA5 || || Putative orotate phosphoribosyltransferase; protein abundance is affected by URA3 expression in the CAI-4 strain background; flucytosine induced; protein level decreased in stationary phase cultures || 1 0.05 -0.67 -0.82 -0.79 0.43 0.47 -0.33 0.13 -0.94 0.20 0.58 0.59 -0.49 -0.16 -0.09 -0.08
9425 || orf19.3517 || || || Ortholog(s) have Dsc E3 ubiquitin ligase complex, endoplasmic reticulum, fungal-type vacuole lumen localization || 1 -0.29 -0.44 -0.73 -0.66 0.10 -0.06 -0.58 0.04 -0.55 -0.10 0.69 -0.10 -0.80 -0.76 0.68 -0.03
9426 || orf19.5076 || PFY1 || || Profilin; functional homolog of S. cerevisiae Pfy1; hyphae, macrophage/pseudohyphal-induced; regulated by Nrg1, Tup1; gene lacks intron (unlike S. cerevisiae PFY1); complements growth of S. cerevisiae srv2 mutant; nonessential || 1 -0.31 -0.19 -0.75 -0.63 -0.15 -0.13 0.36 0.25 -0.16 -0.05 0.69 0.19 -0.69 -0.48 0.39 0.05
9427 || orf19.2676 || || || Predicted hexameric RecA-like ATPase Elp456 Elongator subcomplex subunit; required for modification of wobble nucleosides in tRNA; Spider biofilm induced || 1 -0.27 0.09 -1.06 -0.29 -0.00 0.57 0.11 0.01 -0.91 -0.05 0.02 0.03 -0.57 -0.33 -0.26 -0.20
9428 || orf19.4822 || LIP10 || || Secreted lipase, member of a lipase gene family whose members are expressed differentially in response to carbon source and during infection; may have a role in nutrition and/or in creating an acidic microenvironment || 1 -0.15 -0.15 -0.50 -0.30 -0.40 0.49 -0.35 -0.05 0.06 0.21 -0.11 -0.45 -0.54 -0.03 -0.56
9429 || orf19.2805 || PEX8 || || Putative peroxisomal biogenesis factor; expression regulated during planktonic growth || 1 -0.22 -0.30 -0.02 -0.28 -0.35 -0.43 -0.14 -0.16 -0.06 -0.14 -0.55 0.34 -0.19 -0.23 0.34 -0.20
9430 || orf19.5943 || || || Ortholog(s) have role in peroxisome organization and peroxisomal membrane localization || 1 -0.10 -0.20 -0.34 -0.15 -0.05 -0.41 -0.04 -0.37 0.04 0.10 -0.34 0.56 -0.07 -0.15 0.68 -0.21
9431 || orf19.3876 || ZCF19 || || Predicted Zn(II)2Cys6 transcription factor || 1 -0.75 -0.84 -0.49 -0.30 0.06 0.48 -0.75 -0.73 0.53 0.25 -0.17 1.11 -0.33 -0.42 0.56 0.09
9432 || orf19.5399 || IFF11 || || Secreted protein required for normal cell wall structure and for virulence; member of the IFF family; Hap43p-repressed gene || 1 -0.49 -0.36 -0.53 -0.52 0.04 0.15 -0.50 -0.75 0.18 -0.29 -0.30 0.44 -0.33 -0.60 0.19 0.08
9433 || orf19.2906 || PGA41 || || Putative GPI-anchored protein; adhesin-like protein || 1 -0.84 -0.79 -0.53 -0.31 -0.51 0.49 -0.75 -0.63 0.22 -0.29 -0.86 0.52 -0.00 -0.28 0.36 -0.76
9434 || orf19.2962 || || || Protein of unknown function; Spider biofilm induced || 1 -1.99 -1.84 -1.73 -0.78 -1.75 0.26 -0.30 -2.20 -0.73 -1.20 -1.63 1.58 0.49 -1.04 0.73 -0.60
9435 || orf19.7468 || || || Putative transcriptional activator; expression upregulated during growth in the mouse cecum; Spider biofilm induced || 1 -0.27 -0.38 -0.66 -0.47 -0.67 -0.46 -0.76 -1.67 -0.32 -0.16 -0.90 0.10 0.21 -0.75 0.50 -0.17
9436 || orf19.7468 || || || Putative transcriptional activator; expression upregulated during growth in the mouse cecum; Spider biofilm induced || 1 -0.19 -0.10 -0.31 -0.04 -0.28 0.00 -0.75 -1.70 -0.08 -0.25 -0.67 0.52 0.48 -0.62 0.70 -0.66
9437 || orf19.7645 || || || Biotin protein ligase; catalyzes covalent attachment of biotin to biotin-dependent enzymes including acetyl CoA carboxylase and pyruvate carboxylase || 1 -0.23 -0.25 -1.00 -0.36 -0.39 0.33 -1.38 -1.00 -0.18 0.09 -1.24 0.53 0.52 0.25 1.06 -0.56
9438 || orf19.7645 || || || Biotin protein ligase; catalyzes covalent attachment of biotin to biotin-dependent enzymes including acetyl CoA carboxylase and pyruvate carboxylase || 1 -0.61 -0.51 -1.48 -0.83 -0.32 0.22 -1.43 -1.41 -0.33 0.01 -1.23 0.05 0.17 -0.34 0.78 -0.53
9439 || orf19.7646 || || || Ortholog(s) have role in box C/D snoRNP assembly, protein folding, rRNA processing, regulation of cell size and R2TP complex, cytoplasm, nucleus, small nucleolar ribonucleoprotein complex localization || 1 -0.24 -0.34 -0.69 -0.69 0.32 0.41 -0.80 -0.92 -0.16 -0.48 -0.99 0.19 0.48 0.00 0.69 0.01
9440 || orf19.3818 || GOA1 || || Protein required for respiratory growth, resistance to oxidants, chlamydospore formation, hyphal growth under some conditions, and virulence; relocalizes from the cytoplasm to the mitochondrion during oxidative or osmotic stress || 1 -0.13 -0.58 -0.09 -0.07 -0.07 0.33 -0.21 -0.27 -0.64 -0.60 -0.32 -0.46 -0.28 -0.28 -0.47 -0.02
9441 || orf19.5306 || || || Ortholog of C. dubliniensis CD36 : Cd36_43820 and Candida albicans WO-1 : CAWG_03393 || 1 -0.60 -0.49 0.35 0.50 0.66 0.27 -1.58 -1.33 0.19 -0.10 -1.31 0.04 -0.92 -1.23 -0.05 -1.46
9442 || orf19.4997 || KIS2 || || Scaffold protein of Snf1p complex; similar to S. cerevisiae Gal83p and Sip2p; interacts with Snf4p; interaction with Snf1p complex is regulated by carbon source, decreased on ethanol; N-terminal myristoylation; Hog1p-downregulated || 1 -0.49 -0.53 -0.17 -0.34 0.46 0.15 -0.98 -0.66 0.42 0.08 -0.91 -0.11 -0.56 -0.81 -0.32 -1.29
9443 || orf19.4863 || PDC2 || || Homeodomain-like transcription factor; regulator of pyruvate decarboxylase; contains a putative C-terminal activation domain, Glu- and Pro-rich; complements glucose utilization defect of S. cerevisiae pdc2 mutant || 1 -1.30 -1.06 -0.30 -0.28 0.85 0.76 -1.05 -1.18 0.47 0.03 -1.34 0.15 -0.97 -0.17 0.22 -0.68
9444 || orf19.6208 || MEF2 || || Putative mitochondrial translation elongation factor; caspofungin induced || 1 -0.67 -0.33 -0.20 0.09 0.31 0.54 -0.73 -0.55 -0.01 -0.04 -0.70 -0.12 0.11 -0.44 -0.16 -0.22
9445 || orf19.6203 || PUT3 || || Zn(II)2Cys6 transcription factor; has similarity to S. cerevisiae Put3, a transcription factor involved in the regulation of proline utilization genes || 1 -0.23 -0.36 0.07 -0.18 0.03 0.16 -0.35 -0.63 0.31 -0.12 -0.43 -0.21 -0.31 -0.28 -0.15 0.02
9446 || orf19.399 || || || Putative serine/threonine protein kinase; possibly an essential gene, disruptants not obtained by UAU1 method || 1 -0.26 -0.42 -0.17 -0.02 -0.01 0.00 -0.34 -0.68 -0.46 -0.38 -0.05 -0.52 -0.35 -0.46 0.45 0.03
9447 || orf19.5626 || || || Protein of unknown function; Plc1-regulated; induced by Mnl1 under weak acid stress; flow model biofilm induced || 1 -0.61 -0.44 -0.46 -0.07 -0.04 0.41 -1.17 -1.62 -1.02 -1.28 -0.27 -0.91 -0.65 0.26 1.62 0.35
9448 || orf19.5626 || || || Protein of unknown function; Plc1-regulated; induced by Mnl1 under weak acid stress; flow model biofilm induced || 1 -0.95 -0.82 -0.36 0.01 -0.49 0.23 -1.50 -1.73 -1.12 -1.34 -0.49 -0.65 -1.22 0.51 1.18 0.48
9449 || orf19.697 || || || Ortholog(s) have mitochondrial outer membrane localization || 1 -0.00 -0.08 -0.34 -0.19 0.12 0.20 -0.24 -0.56 -0.50 -0.84 -0.62 0.01 -0.50 0.20 0.36 0.11
9450 || orf19.6371 || || || Ortholog of C. dubliniensis CD36 : Cd36_33750, C. parapsilosis CDC317 : CPAR2_205650, Candida tenuis NRRL Y-1498 : cten_CGOB_00253 and Debaryomyces hansenii CBS767 : DEHA2A11088g || 1 -0.61 -0.31 -0.40 -0.48 0.09 0.38 -0.56 -0.49 -0.32 0.04 -0.26 -0.11 -0.29 0.41 -0.14 -0.06
9451 || orf19.6288 || || || Dubious open reading frame || 1 -1.10 -0.91 -0.37 -0.53 0.54 0.86 -1.42 -1.13 -0.99 -0.33 -0.41 -0.02 -0.96 0.51 -0.35 -0.14
9452 || orf19.3589 || SPO11 || || DNA endonuclease; required for genetic recombination between homologous chromosomes during the parasexual cycle; produced in mitotically dividing cells; similar to S. cerevisiae Spo11 which functions in recombination during meiosis || 1 -1.19 -1.02 -0.48 -0.67 1.04 0.85 -0.68 -1.07 -0.80 -0.32 -0.24 -0.61 -0.71 0.50 0.57 0.25
9453 || orf19.3368 || || || Ortholog of Candida albicans WO-1 : CAWG_03466 || 1 -1.98 -1.28 -0.44 0.19 0.27 1.60 -0.86 -1.86 -0.25 -0.72 -0.62 -1.41 -0.25 0.68 0.05
9454 || orf19.6577 || FLU1 || || Multidrug efflux pump of the plasma membrane; MDR family member of the MFS (major facilitator superfamily) of transporters; involved in histatin 5 efflux; fungal-specific (no human/murine homolog) || 1 -0.95 -1.00 -0.66 -0.39 -0.08 0.90 -0.52 -1.13 -1.38 -0.13 -0.48 -0.48 -0.98 -0.15 0.10 -0.12
9455 || orf19.2783 || PIR32 || || Cell wall protein, putative structural component of the cell wall; mutation leads to increased chitin content, increased virulence and resistance to stresses; macrophage-induced gene || 1 -1.84 -1.62 -0.28 0.18 -1.28 -0.62 -2.73 -0.71 -0.41 -0.34 -1.12 -0.09 0.63 -0.56
9456 || orf19.6271 || || || Ortholog(s) have role in mRNA splicing, via spliceosome and nucleus, transcriptionally active chromatin localization || 1 -0.64 -0.53 -0.01 -0.05 0.09 0.52 -0.43 -0.45 -0.43 -0.24 -0.11 0.02 -0.08 -0.03 -0.05 -0.28
9457 || orf19.956 || || || Ortholog(s) have role in fermentation and mitochondrion localization || 1 -0.50 -0.68 0.04 -0.13 0.65 0.83 -0.28 -0.51 -0.44 -0.44 -0.43 -0.30 -0.27 -0.39 0.05 0.08
9458 || orf19.1333 || SNG3 || || Putative membrane transporter; Hap43p-induced gene; mutation confers hypersensitivity to toxic ergosterol analog; shows colony morphology-related gene regulation by Ssn6p || 1 -0.42 -0.31 0.17 -0.10 0.21 0.94 -0.37 -0.28 -0.36 -0.30 -0.18 -0.02 -0.18 -0.24 0.14 -0.35
9459 || orf19.5785 || || || Protein of unknown function; upregulated in a cyr1 or ras1 null mutant; induced by nitric oxide || 1 -0.88 -0.74 0.23 -0.63 0.20 1.55 -0.60 -0.73 -0.52 -1.23 0.04 -0.30 -0.44 -0.41 0.17 -0.23
9460 || orf19.5785 || || || Protein of unknown function; upregulated in a cyr1 or ras1 null mutant; induced by nitric oxide || 1 -1.36 -1.47 -0.54 -0.87 0.21 1.63 -0.81 -0.92 -1.30 -1.32 0.32 -0.37 -0.62 -0.42 0.58 -0.09
9461 || orf19.6997 || ATO5 || || Putative fungal-specific transmembrane protein || 1 -0.59 -1.33 -0.26 -0.89 0.04 2.18 -1.40 -1.54 -1.77 -0.86 -0.93 -0.25 -0.31 0.89 0.07
9462 || orf19.6653 || MTG2 || || Putative Obg family GTPase member; peripheral protein of the mitochondrial inner membrane; associates with the large ribosomal subunit; required for mitochondrial translation; rat catheter biofilm repressed || 1 -0.39 -0.52 0.03 -0.21 0.39 0.67 -0.41 -0.31 -0.25 0.56 -0.54 -0.06 -0.50 -0.16 0.12 -0.13
9463 || orf19.7387 || ELP3 || || Predicted histone acetyltransferase; role in regulation of transcription, tRNA wobble uridine modification; Spider biofilm induced || 1 -0.52 -0.49 -0.05 -0.41 0.53 1.23 -0.61 -0.77 -0.78 0.62 -0.87 -0.34 -0.64 -0.70 0.47 -1.08
9464 || orf19.7387 || ELP3 || || Predicted histone acetyltransferase; role in regulation of transcription, tRNA wobble uridine modification; Spider biofilm induced || 1 -0.67 -0.64 -0.15 -0.37 0.46 1.44 -0.91 -1.02 -1.15 0.42 -0.64 0.01 -1.07 -0.65 0.50 -0.72
9465 || orf19.1047 || ERB1 || || Protein with a predicted role in ribosomal large subunit biogenesis; mutation confers hypersensitivity to 5-fluorocytosine (5-FC), 5-fluorouracil (5-FU), and tubercidin (7-deazaadenosine); hyphal, macrophage repressed || 1 -0.66 -0.65 -0.59 -0.27 0.69 1.12 -1.10 -1.05 -0.84 0.05 -0.55 -0.29 -0.90 -0.60 0.55 -0.94
9466 || orf19.1923 || RRN3 || || Protein with a predicted role in recruitment of RNA polymerase I to rDNA; caspofungin induced; flucytosine repressed; repressed in core stress response; repressed by prostaglandins || 1 -0.79 -0.46 -0.36 -0.21 1.14 1.57 -1.40 -1.38 -1.31 -0.06 -0.66 -0.94 -0.77 -1.31 0.07 -0.47
9467 || orf19.4401 || YVH1 || || Putative dual specificity phosphatase (phosphoserine/threonine and phosphotyrosine phosphatase); required for wild-type growth rate and for wild-type virulence in mouse model of systemic infection; Hap43p-induced gene || 1 -0.69 -0.65 -0.44 -0.53 0.72 1.47 -0.88 -1.00 -1.03 0.30 -0.49 -0.71 -1.01 -0.21 -0.15 -0.03
9468 || orf19.3539 || || || Predicted nucleolar S-adenosylmethionine-dependent rRNA methyltransferase; Spider biofilm induced || 1 -0.47 -0.49 -0.12 -0.04 0.42 1.26 -0.87 -0.69 -0.60 0.62 -0.82 -0.85 -0.54 -0.41 -0.35 -0.52
9469 || orf19.329 || || || Putative pre-mRNA branch point binding protein; role in mRNA splicing via spliceosome; Spider biofilm repressed || 1 -0.12 -0.14 -0.14 -0.08 -0.01 0.35 -0.39 -0.26 -0.55 0.01 -0.50 -0.14 -0.47 -0.18 -0.06 -0.28
9470 || orf19.6347 || || || Pre-mRNA splicing factor; important for catalytic step II of pre-mRNA splicing; possible role in cell cycle progression; Spider biofilm induced || 1 -0.37 -0.40 -0.00 -0.30 0.10 1.03 -0.52 -0.61 -0.75 0.13 -0.66 -0.14 -0.27 -0.10 -0.49 -0.09
9471 || orf19.3506 || DBR1 || || Debranchase; homozygous mutant accumulates lariat intermediates of mRNA splicing; rat catheter biofilm repressed || 1 -0.34 -0.24 -0.35 -0.46 0.47 0.51 -0.38 -0.58 -0.51 -0.14 -0.52 -0.05 -0.32 0.23 -0.42 0.03
9472 || orf19.6356 || || || Ortholog(s) have role in mRNA splicing, via spliceosome and U4/U6 x U5 tri-snRNP complex localization || 1 -0.50 -0.18 -0.18 -0.49 0.98 1.25 -0.47 -0.90 -0.75 -0.12 -0.80 -0.09 -0.76 -0.01 -0.08 0.23
9473 || orf19.2690 || || || Putative mitochondrial GTPase; required for mitochondrial morphology and genome maintenance; Spider biofilm induced || 1 0.00 -0.09 0.26 0.01 0.34 0.39 -0.67 -0.53 -0.24 -0.44 -0.95 -0.26 -0.76 -0.42 0.17 0.09
9474 || orf19.7258 || DDI1 || || Putative DNA damage inducible v-SNARE binding protein; macrophage/pseudohyphal-repressed || 1 -0.21 -0.34 0.19 0.14 0.41 0.66 -0.88 -0.90 -0.24 -0.38 -0.44 0.01 -1.52 -1.00 0.09 0.06
9475 || orf19.5730 || || || Putative phenylacrylic acid decarboxylase; clade-associated gene expression || 1 -0.17 -0.33 -0.54 -0.63 0.23 0.63 -1.47 -1.84 -0.97 -1.10 -1.15 -0.19 -2.43 -0.86 -0.04 0.23
9476 || orf19.5730 || || || Putative phenylacrylic acid decarboxylase; clade-associated gene expression || 1 0.05 -0.07 -0.01 -0.30 0.39 0.73 -1.60 -2.05 -0.95 -1.21 -1.03 -0.39 -2.20 -0.98 -0.24 0.05
9477 || orf19.5730 || || || Putative phenylacrylic acid decarboxylase; clade-associated gene expression || 1 0.26 -0.03 -0.28 0.00 0.49 0.72 -1.22 -1.41 -0.88 -0.96 -1.02 0.03 -1.90 -0.69 0.19 0.04
9478 || orf19.3922 || || || Possible pyrimidine 5' nucleotidase; protein present in exponential and stationary growth phase yeast cultures; Hap43p-repressed gene || 1 0.56 0.50 -0.04 -0.21 0.76 1.18 -1.96 -2.05 -1.84 -1.87 -0.34 -0.93 -2.48 -1.55 -0.50 -0.50
9479 || orf19.201 || || || Protein of unknown function; unmerged from orf19.202 in a revision of Assembly 21 || 1 0.44 0.32 0.11 0.12 0.65 0.88 -0.79 -0.63 -0.52 -0.65 -0.40 -0.27 -1.51 -0.28 -0.36 -0.04
9480 || orf19.4611 || || || Ortholog(s) have ribose phosphate diphosphokinase activity, role in 5-phosphoribose 1-diphosphate biosynthetic process, cytokinesis, fungal-type cell wall organization and cytosol localization || 1 0.15 0.02 0.10 -0.22 0.19 0.95 -0.66 -0.69 -0.59 -0.12 -0.61 -0.35 -0.75 -0.12 -0.18 -0.36
9481 || orf19.4611 || || || Ortholog(s) have ribose phosphate diphosphokinase activity, role in 5-phosphoribose 1-diphosphate biosynthetic process, cytokinesis, fungal-type cell wall organization and cytosol localization || 1 0.26 0.03 0.12 0.01 0.33 0.85 -0.74 -0.87 -0.44 0.04 -0.79 -0.27 -0.78 -0.22 -0.15 -0.22
9482 || orf19.5604 || MDR1 || || Plasma membrane MDR/MFS multidrug efflux pump; methotrexate is preferred substrate; overexpression in drug-resistant clinical isolates confers fluconazole resistance; repressed in young biofilms; rat catheter biofilm induced || 1 0.54 0.12 -0.89 -0.05 0.95 2.16 -1.69 -2.43 -1.77 -0.15 -2.05 -1.08 -2.60 -1.18 -1.15 -0.65
9483 || orf19.5217 || TES1 || || Putative acyl-CoA thioesterase || 1 -0.01 -0.20 -0.31 -0.03 -0.05 0.87 -0.69 -0.91 -0.43 -0.22 -0.49 -0.31 -0.93 -0.49 -0.24 -0.25
9484 || orf19.5758 || SAL6 || || Putative protein phosphatase of the Type 1 family; serine/threonine-specific; similar to S. cerevisiae Ppq1; mutant has virulence defect; Spider biofilm induced || 1 -0.01 -0.15 0.27 0.63 -0.68 0.38 -1.11 -1.02 -0.67 -0.32 -0.83 0.21 -0.61 -0.47 0.00 -0.08
9485 || orf19.1890 || || || Ortholog(s) have role in medium-chain fatty acid biosynthetic process || 1 0.27 0.22 0.34 0.16 -0.37 0.50 -1.22 -1.12 -1.14 -0.23 -1.05 -0.14 -0.66 -0.51 0.00 0.04
9486 || orf19.696 || STE2 || || Receptor for alpha factor mating pheromone, MFalpha; required for a-type cells to respond to alpha factor, for opaque a-form mating and white a-form response; possible Kex2p substrate; a-specific, alpha-factor induced, A1p-Alpha2p repressed || 1 0.17 0.08 0.41 0.29 -0.13 0.90 -1.77 -2.02 -1.16 -1.15 -2.06 -0.36 -1.16 -1.23 -0.38 -0.13
9487 || orf19.696 || STE2 || || Receptor for alpha factor mating pheromone, MFalpha; required for a-type cells to respond to alpha factor, for opaque a-form mating and white a-form response; possible Kex2p substrate; a-specific, alpha-factor induced, A1p-Alpha2p repressed || 1 0.15 0.04 0.33 0.25 -0.04 0.80 -1.77 -2.06 -1.04 -0.96 -1.97 -0.82 -0.93 -1.38 -0.41 -0.78
9488 || orf19.5710 || || || Nucleoporin component of central core of the nuclear pore complex; mRNA binds She3 || 1 -0.18 -0.29 0.35 0.26 0.35 0.40 -0.79 -0.71 -0.39 -0.43 -0.46 -0.23 -0.22 -0.79 -0.19 0.04
9489 || orf19.5960 || NCE102 || || Non classical protein export protein; localized to plasma membrane; Hap43-induced gene; flow model biofilm induced; Spider biofilm induced || 1 -0.37 -0.31 0.16 0.70 0.16 0.89 -1.62 -1.59 -1.18 -0.91 -1.11 -0.26 -0.76 -1.47 0.62 -0.51
9490 || orf19.4199 || SLY41 || || Protein involved in ER-to-Golgi transport; rat catheter and Spider biofilm induced || 1 -0.30 -0.35 0.18 0.74 -0.00 0.58 -1.14 -1.17 -0.81 -0.60 -0.32 0.11 -0.81 -0.60 -0.05 -0.22
9491 || orf19.862 || || || Protein of unknown function; Spider biofilm induced || 1 -0.28 -0.46 0.38 0.32 -0.40 0.20 -1.33 -1.02 -0.78 -0.36 -0.46 0.08 -0.81 -0.40 -0.13 -0.66
9492 || orf19.7663 || || || Ortholog(s) have role in homologous chromosome segregation, protein localization to nucleolar rDNA repeats, rDNA condensation and monopolin complex, nuclear envelope, nucleolus localization || 1 -0.19 -0.17 0.16 0.12 -0.18 0.26 -0.65 -0.61 -0.74 -0.29 -0.58 -0.30 -0.55 -0.19 -0.25 -0.59
9493 || orf19.480 || || || Protein of unknown function; rat catheter and Spider biofilm induced || 1 -0.14 -0.29 0.17 0.22 0.29 0.79 -0.58 -1.21 -1.00 0.01 -0.93 -0.32 -0.54 -0.38 0.05 -0.48
9494 || orf19.5162 || BCK1 || || Ortholog of S. cerevisiae Bck1; MAP kinase kinase kinase of cell integrity pathway; mutant is hypersensitive to caspofungin || 1 -0.04 -0.31 0.41 0.11 0.19 0.12 -0.46 -0.43 -0.18 -0.20 -0.44 -0.25 -0.39 -0.16 -0.03 -0.07
9495 || orf19.6449 || || || Ortholog of C. dubliniensis CD36 : Cd36_34310 || 1 -0.66 -0.66 0.97 0.67 0.59 1.03 -1.50 -1.69 -0.90 -0.94 -1.33 -0.55 -1.15 -0.42 -0.71 -0.05
9496 || orf19.3738 || PGA22 || || Putative GPI-anchored protein; adhesin-like protein || 1 -0.48 -0.38 0.52 0.87 0.16 0.99 -1.31 -1.36 -0.18 -0.59 -1.11 -0.73 -0.49 -1.01 -0.88 -0.28
9497 || orf19.5986 || THI4 || || Thiamine biosynthetic enzyme precursor; repressed during the mating process; stationary phase enriched protein; Spider biofilm induced || 1 -0.29 -0.19 0.76 1.07 0.68 0.95 -1.04 -1.26 0.07 -1.02 -1.53 -0.95 -0.69 -0.46 -0.66 -0.33
9498 || orf19.5823 || SGT2 || || Putative small tetratricopeptide repeat (TPR)-containing protein; protein abundance is affected by URA3 expression in the CAI-4 strain background; Mig1-regulated || 1 -0.38 -0.25 0.58 0.71 -0.04 0.40 -1.01 -0.73 -0.17 -0.27 -0.69 -0.40 -0.44 -0.12 -0.22 -0.11
9499 || orf19.6475 || || || Protein of unknown function; flow model biofilm induced || 1 -0.37 -0.35 0.23 0.15 -0.11 0.39 -0.54 -0.55 -0.04 -0.23 -0.41 -0.35 -0.48 -0.07 -0.10 -0.02
9500 || orf19.5710 || || || Nucleoporin component of central core of the nuclear pore complex; mRNA binds She3 || 1 -0.30 -0.00 0.12 0.16 0.03 0.17 -0.31 -0.33 -0.19 -0.34 -0.53 0.04 -0.32 -0.17 -0.19 -0.01
9501 || orf19.7420 || || || Ortholog(s) have RNA polymerase II transcription coactivator activity involved in preinitiation complex assembly activity || 1 -0.35 -0.28 0.22 0.31 0.00 0.53 -0.55 -0.56 -0.05 -0.78 -0.34 0.28 -0.13 -0.55 -0.14 -0.28
9502 || orf19.2106 || || || Putative protein of unknown function; Hap43p-repressed gene || 1 -0.25 -0.14 0.14 0.32 -0.01 -0.01 -0.54 -0.57 -0.17 -0.71 -0.22 -0.03 -0.24 -0.51 -0.44 -0.26
9503 || orf19.5526 || SEC20 || || Essential protein; similar to S. cerevisiae Sec20p; depletion causes membrane accumulation and drug sensitivity; expression regulated by growth phase; O-mannosylation regulates proteolysis; does not complement S. cerevisiae sec20-1 mutant || 1 -0.48 -0.39 0.08 0.09 -0.24 0.06 -0.63 -0.50 -0.16 -0.85 -0.45 -0.06 -0.18 -0.28 -0.61 -0.16
9504 || orf19.7266 || || || Ortholog of Candida albicans WO-1 : CAWG_00007 || 1 -0.44 -0.30 0.06 -0.02 -0.15 -0.09 -0.77 -0.72 -0.04 -0.86 -0.63 0.07 -0.04 -0.58 -0.34 -0.31
9505 || orf19.2966 || || || Predicted dienelactone hydrolase domain; clade-associated gene expression; farnesol-downregulated; rat catheter biofilm repressed || 1 -0.58 -0.43 0.04 0.04 -0.20 0.11 -0.91 -0.90 0.16 -1.00 -0.73 -0.14 -0.09 -0.41 -0.23 -0.35
9506 || orf19.879 || || || Ortholog(s) have myosin binding activity, role in intracellular mRNA localization, mating type switching and cytoplasm localization || 1 -0.16 -0.13 -0.08 0.02 0.18 0.16 -0.51 -0.50 -0.28 -0.56 -0.39 0.14 -0.09 -0.27 -0.14 -0.07
9507 || orf19.6070 || ENA2 || || Putative sodium transporter; induced by ciclopirox olamine; alkaline induced by Rim101; repressed by high-level peroxide stress; induced in oral candidiasis clinical isolates; possibly essential gene; rat catheter and Spider biofilm induced || 1 -0.46 -0.60 -0.30 -0.26 -0.02 0.12 -0.49 -0.74 -0.85 -1.16 -0.47 0.14 -0.35 -1.04 0.00 -0.38
9508 || orf19.2258 || || || Ortholog of C. dubliniensis CD36 : Cd36_21310, C. parapsilosis CDC317 : CPAR2_406650, Candida tenuis NRRL Y-1498 : CANTEDRAFT_130046 and Debaryomyces hansenii CBS767 : DEHA2F24134g || 1 -0.25 -0.28 0.06 0.23 -0.01 0.22 -0.48 -0.35 -0.67 -0.68 -0.38 0.15 -0.25 -0.54 -0.03 -0.45
9509 || orf19.750 || || || Protein of unknown function; exogenously expressed protein is a substrate for Kex2p processing in vitro || 1 -0.53 -0.53 0.72 0.28 -0.37 0.54 -0.83 -1.22 -0.86 -1.71 -0.87 0.24 -0.46 -1.53 -0.75 -0.30
9510 || orf19.333 || FCY2 || || Purine-cytosine permease of pyrimidine salvage; mutation associated with resistance to flucytosine in clinical isolates; transposon mutation affects filamentation; farnesol-upregulated in biofilm || 1 -0.37 -0.34 0.11 -0.25 -0.07 0.33 -0.57 -0.52 -0.39 -1.02 -0.52 -0.20 -0.29 -0.90 -0.37 0.05
9511 || orf19.3395 || || || Predicted MFS membrane transporter, member of the drug:proton antiporter (12 spanner) (DHA1) family; induced by nitric oxide, oxidative stress, alpha pheromone; fungal-specific; Hap43-repressed; Spider biofilm induced || 1 -0.47 -0.03 0.02 -0.38 -0.22 0.47 -0.74 -1.08 -0.63 -1.71 -0.62 -0.65 0.14 -1.03 -0.41 -0.26
9512 || orf19.4372 || || || Predicted transmembrane transporter; rat catheter and Spider biofilm induced || 1 -0.66 -0.49 -0.25 -0.35 0.14 -0.20 -0.65 -1.18 -0.48 -1.60 -0.91 -1.14 -0.97 -0.09 -0.79 0.13
9513 || orf19.4372 || || || Predicted transmembrane transporter; rat catheter and Spider biofilm induced || 1 -0.78 -0.65 -0.13 -0.54 -0.02 -0.36 -0.74 -1.22 -0.61 -1.63 -0.96 -0.96 -0.88 -0.24 -0.62 0.21
9514 || orf19.5133 || ZCF29 || || Zn(II)2Cys6 transcription factor; mutants sensitive to caffeine and menadione, resistant to fenpropimorph; Hap43-repressed; mutants have decreased CFU in mouse kidneys and defects in filamentous growth; Spider biofilm induced || 1 -0.62 -0.56 -0.23 -0.08 0.00 -0.27 -0.98 -1.47 -0.68 -1.66 -0.67 -0.55 -0.23 -0.36 -0.15 -0.04
9515 || orf19.5132 || || || Protein of unknown function; transcript detected on high-resolution tiling arrays; Spider biofilm induced || 1 -0.09 0.00 -0.19 0.14 0.06 0.01 -0.45 -1.08 -0.61 -1.22 -0.56 -0.77 -0.10 -0.28 -0.14 -0.67
9516 || orf19.3215 || || || Putative plasma membrane protein; in S. cerevisiae it is localized to the cell bud and mating projection membrane; repressed by alpha pheromone in SpiderM medium || 1 -0.19 -0.31 -0.01 -0.01 -0.22 -0.09 -1.28 -1.70 -1.27 -1.57 -1.65 -1.32 -0.38 -0.70 -0.42 -1.07
9517 || orf19.3004 || || || Ortholog(s) have fungal-type vacuole localization || 1 -0.21 -0.28 -0.26 -0.44 0.28 0.40 -0.86 -1.27 -0.89 -1.34 -0.94 -1.12 -0.30 -0.66 -0.28 -0.41
9518 || orf19.323 || || || Putative haloacid dehalogenase; localized to plasma membrane || 1 -0.29 -0.55 -0.50 -0.51 -0.37 -0.13 -1.63 -1.62 -1.98 -1.57 -1.05 -1.23 -1.01 -0.76 -1.12 -0.59
9519 || orf19.323 || || || Putative haloacid dehalogenase; localized to plasma membrane || 1 -0.05 -0.11 -0.25 -0.31 -0.09 0.48 -1.14 -1.18 -1.74 -1.15 -0.62 -0.54 -0.67 -0.65 -0.61 -0.23
9520 || orf19.7445 || || || Ortholog of S.c. Vid24; a peripheral membrane protein located at Vid (vacuole import and degradation) vesicles; regulated by Sef1, Sfu1, and Hap43; Spider biofilm induced || 1 -0.42 -0.35 -0.29 -0.62 0.10 0.58 -1.81 -1.88 -1.69 -1.78 -0.82 -0.55 -0.77 -0.66 -1.00 0.10
9521 || orf19.2559 || CDC4 || || F-box subunit of SCF(CDC4) ubiquitin ligase; functional homolog of S. cerevisiae Cdc4; mutation/depletion causes hyperfilamentation; Sol1 is a substrate of SCF-Cdc4; Spider biofilm induced || 1 0.10 -0.13 -0.08 -0.34 -0.11 0.22 -0.70 -0.77 -0.42 -0.45 -0.73 -0.37 -0.45 -0.25 -0.27 0.01
9522 || orf19.7445 || || || Ortholog of S.c. Vid24; a peripheral membrane protein located at Vid (vacuole import and degradation) vesicles; regulated by Sef1, Sfu1, and Hap43; Spider biofilm induced || 1 -0.17 -0.16 0.09 -0.12 0.31 0.88 -1.11 -1.30 -1.12 -1.50 -0.57 -0.77 -0.49 -0.24 -0.58 0.26
9523 || orf19.3004 || || || Ortholog(s) have fungal-type vacuole localization || 1 0.04 0.08 0.12 -0.35 0.50 0.63 -0.80 -1.09 -0.59 -1.19 -0.71 -0.62 -0.25 0.06 -0.09 0.05
9524 || orf19.7105 || FAR1 || || Protein involved in regulation of pheromone-mediated mating; repressed by A1p and Alpha2p in white-phase cells; null mutant shows no pheromone response in opaque cells; overexpression causes enhanced pheromone response and cell cycle arrest || 1 -0.27 -0.30 0.72 0.60 0.05 0.24 -1.16 -1.46 -0.99 -1.60 -1.20 -0.56 -0.35 -0.58 -0.09 -0.69
9525 || orf19.3136 || || || Ortholog(s) have transcription coactivator activity, role in DNA repair, cellular carbohydrate metabolic process and cytoplasm localization || 1 -0.06 -0.35 0.43 0.22 -0.26 0.09 -0.88 -1.05 -0.52 -1.19 -0.45 -0.30 -0.50 -0.43 0.03 -0.07
9526 || orf19.3136 || || || Ortholog(s) have transcription coactivator activity, role in DNA repair, cellular carbohydrate metabolic process and cytoplasm localization || 1 -0.25 -0.51 0.06 0.22 -0.37 -0.02 -0.97 -1.11 -0.60 -1.03 -0.54 -0.21 -0.65 -0.44 -0.02 -0.23
9527 || orf19.4754 || ZWF1 || || Glucose-6-phosphate dehydrogenase; antigenic in mice; activity induced by O2 or oxidizing agents H2O2, menadione, macrophage; caspofungin repressed; induced in core stress response; regulated by Gcn2, Gcn4; rat catheter biofilm repressed || 1 -0.11 -0.14 0.11 -0.04 -0.45 -0.13 -0.58 -0.76 -0.40 -0.65 -0.43 -0.05 -0.29 0.02 -0.08 -0.20
9528 || orf19.206 || || || Putative adhesin-like protein || 1 -0.43 -0.29 0.51 -0.05 -0.11 0.10 -0.44 -0.62 -0.61 -0.56 -0.69 -0.19 -0.28 -0.27 -0.23 -0.13
9529 || orf19.3395 || || || Predicted MFS membrane transporter, member of the drug:proton antiporter (12 spanner) (DHA1) family; induced by nitric oxide, oxidative stress, alpha pheromone; fungal-specific; Hap43-repressed; Spider biofilm induced || 1 -0.55 -0.56 0.30 -0.08 0.09 0.91 -0.74 -1.46 -0.89 -1.53 -0.54 -0.27 0.03 -0.80 -0.28 0.43
9530 || orf19.5635 || PGA7 || || GPI-linked hyphal surface antigen; induced by ciclopirox olamine, ketoconazole, Rim101 at pH 8; Hap43, fluconazole; flow model biofilm induced; Spider biofilm induced; required for RPMI biofilm; Bcr1-induced in a/a biofilm || 1 -0.89 -0.65 0.01 -0.14 -0.32 0.13 -0.92 -1.27 -1.11 -2.37 -0.89 -0.81 -0.03 -0.40 -0.29 1.18
9531 || orf19.6077 || || || Putative protein of unknown function; shows colony morphology-related gene regulation by Ssn6p || 1 -1.12 -1.12 -0.11 -0.16 -0.40 0.62 -1.33 -1.69 -1.05 -1.33 -0.83 -0.00 0.48 -0.14 0.40 -0.30
9532 || orf19.6077 || || || Putative protein of unknown function; shows colony morphology-related gene regulation by Ssn6p || 1 -1.20 -1.17 0.40 0.46 -0.26 0.76 -1.81 -1.98 -0.97 -1.36 -0.93 0.11 0.66 -0.60 0.31 -0.49
9533 || orf19.1891 || APR1 || || Vacuolar aspartic proteinase; transcript equivalent in yeast-form and mycelial cells but is elevated at lower growth temperatures; upregulated iby human neutrophils; protein enriched in stationary phase; Spider biofilm induced || 1 -0.46 -0.55 0.11 0.32 -0.28 0.87 -1.53 -2.04 -0.89 -1.51 -1.30 -0.53 0.34 -1.04 0.52 -0.78
9534 || orf19.1891 || APR1 || || Vacuolar aspartic proteinase; transcript equivalent in yeast-form and mycelial cells but is elevated at lower growth temperatures; upregulated iby human neutrophils; protein enriched in stationary phase; Spider biofilm induced || 1 -0.73 -0.83 -0.03 0.08 -0.64 0.56 -1.82 -2.37 -1.29 -1.64 -1.61 -0.59 0.15 -1.04 0.21 -0.85
9535 || orf19.671 || PSP1 || || Protein repressed during the mating process || 1 -0.42 -0.29 -0.10 -0.02 -0.16 -0.22 -0.45 -0.59 -0.31 -0.51 -0.38 -0.04 0.06 -0.24 0.19 -0.14
9536 || orf19.4128 || || || Ortholog of C. dubliniensis CD36 : Cd36_19390, C. parapsilosis CDC317 : CPAR2_209600, Candida tenuis NRRL Y-1498 : CANTEDRAFT_134010 and Debaryomyces hansenii CBS767 : DEHA2C14960g || 1 -0.95 -0.84 -0.52 -0.15 0.69 0.79 -2.57 -2.21 -1.19 -1.19 -1.50 -1.33 -2.49 -1.78 0.78 -3.03
9537 || orf19.6688 || || || Protein of unknown function; expression decreases by benomyl treatment or in an azole-resistant strain overexpressing MDR1; Spider biofilm induced || 1 -1.30 -1.31 -0.29 -0.56 1.36 2.40 -1.75 -4.15 -1.29 -1.00 -3.08 -2.58 -1.31 -3.68 2.68 -4.33
9538 || orf19.6117 || || || S. pombe ortholog SPAC5D6.04 is a predicted auxin family transmembrane transporter; ketoconazole and hypoxia induced || 1 -0.53 -0.58 0.19 0.17 0.50 1.61 -0.87 -0.95 -0.65 -1.30 -0.63 -0.98 -0.12 -0.44 0.31 -0.48
9539 || orf19.2072 || || || Ortholog(s) have (R)-carnitine transmembrane transporter activity, choline transmembrane transporter activity, ethanolamine transmembrane transporter activity || 1 -0.42 -0.04 0.25 0.22 0.36 0.91 -0.68 -0.47 -0.99 -0.52 0.07 -0.10
9540 || orf19.7196 || || || Putative vacuolar protease; upregulated in the presence of human neutrophils; Spider biofilm induced || 1 -0.37 -0.46 0.21 -0.09 -0.09 0.68 -0.89 -1.40 -0.38 -1.08 -1.16 -0.09 0.17 -1.02 0.26 -0.04
9541 || orf19.7196 || || || Putative vacuolar protease; upregulated in the presence of human neutrophils; Spider biofilm induced || 1 -0.80 -0.91 -0.17 -0.55 -0.30 0.49 -0.94 -1.60 -0.43 -1.21 -1.26 -0.01 -0.07 -1.08 0.37 -0.10
9542 || orf19.2242 || PRB1 || || Endoprotease B; regulated by heat, carbon source (GlcNAc-induced), nitrogen, macrophage response, human neutrophils; similar to (does not replace) S. cerevisiae vacuolar B protease Prb1p; flow model biofilm induced; Spider biofilm induced || 1 -0.34 -0.39 -0.35 -0.53 0.05 0.47 -0.88 -1.48 -0.22 -1.26 -1.29 -0.29 0.07 -0.78 0.26 0.06
9543 || orf19.5125 || || || Protein of unknown function; induced by ketoconazole; Spider, F-12/CO2 and flow model biofilm induced || 1 -0.65 -0.57 -0.10 -0.34 0.60 1.22 -1.30 -2.23 -0.64 -1.61 -1.99 -0.31 -0.40 -1.06 1.40 -0.25
9544 || orf19.6877 || PNG2 || || Putative peptide:N-glycanase; gene has variable numbers of 12-bp repeats; induced by caspofungin, ciclopirox olamine, ketoconazole or hypoxia; gene of core caspofungin response; Hap43-induced; Spider biofilm induced || 1 -1.07 -0.92 -0.24 -0.48 0.77 1.33 -1.48 -2.20 -0.81 -2.02 -2.16 -0.75 0.03 -0.81 0.44 -0.23
9545 || orf19.6877 || PNG2 || || Putative peptide:N-glycanase; gene has variable numbers of 12-bp repeats; induced by caspofungin, ciclopirox olamine, ketoconazole or hypoxia; gene of core caspofungin response; Hap43-induced; Spider biofilm induced || 1 -1.02 -0.87 0.02 -0.46 1.12 1.41 -1.34 -1.97 -0.50 -1.65 -1.74 -0.48 0.31 -0.60 0.48 0.01
9546 || orf19.3841 || || || Putative protein serine/threonine kinase; predicted role in vesicle formation in autophagy and the cytoplasm-to-vacuole targeting (Cvt) pathway; Spider biofilm induced || 1 -1.03 -0.60 -0.50 -0.07 1.48 0.89 -1.19 -2.06 -0.27 -0.87 -1.79 -0.06 -0.62 0.28 -0.34
9547 || orf19.4795 || || || Protein of unknown function; Sef1-, Sfu1-, and Hap43 regulated; Spider biofilm induced || 1 -1.04 -0.84 -0.28 -0.72 1.41 1.20 -1.27 -1.51 -0.35 -0.97 -1.56 -0.39 -0.81 -0.61 0.75 -0.30
9548 || orf19.5413 || || || Ortholog(s) have role in mRNA splicing, via spliceosome and Prp19 complex, spliceosomal complex localization || 1 -0.43 -0.22 -0.17 -0.30 0.47 0.73 -0.57 -0.94 -0.46 -0.32 -0.71 -0.35 -0.59 -0.43 0.04 0.07
9549 || orf19.4899 || GCA1 || || Extracellular/plasma membrane-associated glucoamylase; expressed in rat oral infection; regulated by carbohydrates, pH, galactose; promotes biofilm matrix formation; flow model biofilm induced; Bcr1 repressed in RPMI a/a biofilms || 1 -1.75 -1.59 -0.70 -0.62 0.50 1.72 -2.13 -2.38 -0.91 -1.88 -2.54 -1.48 -2.08 -0.86 0.59 -0.73
9550 || orf19.428 || || || Putative serine/threonine kinase; induced during planktonic growth; rat catheter biofilm repressed || 1 -1.07 -1.22 -0.50 -0.80 0.46 1.22 -1.48 -1.48 -0.75 -1.13 -1.27 -0.62 -1.21 -0.24 0.45 -0.18
9551 || orf19.7210 || || || Protein of unknown function; Spider biofilm induced || 1 -1.12 -0.97 -0.37 -0.59 0.42 1.09 -1.64 -2.19 -1.01 -1.34 -1.50 -0.60 -1.65 -0.88 0.51 0.13
9552 || orf19.7210 || || || Protein of unknown function; Spider biofilm induced || 1 -0.89 -1.08 -0.63 -0.67 0.45 1.04 -1.67 -2.11 -0.95 -1.68 -1.48 -0.78 -1.48 -1.23 0.47 0.06
9553 || orf19.7247 || RIM101 || || Transcription factor; alkaline pH response; required for alkaline-induced hyphal growth; role in virulence in mice; activated by C-terminal proteolytic cleavage; mediates both positive and negative regulation; Spider biofilm induced || 1 -0.92 -1.06 -0.32 -0.35 0.30 0.62 -1.09 -1.12 -0.74 -0.83 -0.68 -0.44 -0.74 -0.57 -0.02 -0.26
9554 || orf19.7247 || RIM101 || || Transcription factor; alkaline pH response; required for alkaline-induced hyphal growth; role in virulence in mice; activated by C-terminal proteolytic cleavage; mediates both positive and negative regulation; Spider biofilm induced || 1 -0.56 -0.58 -0.09 -0.33 0.33 0.67 -0.83 -0.89 -0.50 -0.77 -0.46 -0.49 -0.33 -0.37 0.11 -0.15
9555 || orf19.4780 || || || Predicted MFS family membrane transporter, member of the drug:proton antiporter (12 spanner) (DHA1) family; Spider biofilm induced || 1 -0.65 -0.71 0.03 -0.08 0.67 1.10 -1.81 -2.05 -1.02 -1.17 -1.02 -0.14 -1.18 -0.93 0.71 -0.14
9556 || orf19.4780 || || || Predicted MFS family membrane transporter, member of the drug:proton antiporter (12 spanner) (DHA1) family; Spider biofilm induced || 1 -1.08 -1.22 0.26 -0.25 0.60 1.07 -2.74 -3.21 -1.14 -1.25 -1.33 -0.43 -1.48 -0.97 0.27 -0.28
9557 || orf19.7296 || || || Putative cation conductance protein; similar to stomatin mechanoreception protein; plasma-membrane localized; induced by Rgt1; rat catheter and Spider biofilm induced || 1 -1.10 -1.12 -0.27 0.00 1.22 0.79 -2.31 -2.79 -1.01 -1.04 -1.43 0.22 -1.42 -0.70 0.23 -0.76
9558 || orf19.7296 || || || Putative cation conductance protein; similar to stomatin mechanoreception protein; plasma-membrane localized; induced by Rgt1; rat catheter and Spider biofilm induced || 1 -1.02 -1.07 -0.33 -0.30 1.25 0.61 -2.09 -2.84 -1.11 -1.12 -1.49 -0.02 -1.47 -0.70 0.20 -0.51
9559 || orf19.7296 || || || Putative cation conductance protein; similar to stomatin mechanoreception protein; plasma-membrane localized; induced by Rgt1; rat catheter and Spider biofilm induced || 1 -0.83 -1.01 -0.09 -0.31 1.23 0.62 -2.08 -2.48 -0.76 -0.79 -1.29 0.10 -1.30 -0.73 0.30 -0.43
9560 || orf19.7296 || || || Putative cation conductance protein; similar to stomatin mechanoreception protein; plasma-membrane localized; induced by Rgt1; rat catheter and Spider biofilm induced || 1 -1.24 -1.31 -0.37 -0.56 1.13 0.55 -2.23 -2.73 -1.06 -1.03 -1.41 0.19 -1.64 -0.42 0.29 -0.42
9561 || orf19.2451 || PGA45 || || Putative GPI-anchored cell wall protein; repressed in core caspofungin response; Hog1-induced; regulated by Ssn6; Mob2-dependent hyphal regulation; flow model biofilm induced || 1 -0.81 -0.76 -0.38 0.04 0.51 0.48 -1.52 -1.48 -0.73 -0.45 -0.90 -0.37 -1.05 -1.31 0.64 -0.40
9562 || orf19.672 || || || Ortholog(s) have U5 snRNP localization || 1 -0.33 -0.40 -0.20 -0.25 0.27 0.46 -0.32 -0.61 -0.33 -0.41 -0.26 0.00 -0.64 -0.15 0.10 -0.17
9563 || orf19.2084 || CDH1 || || Protein involved in regulation of mitosis; similar to S. cerevisiae Cdh1, which is an APC/C component; transcriptionally induced by Mnl1 under weak acid stress || 1 -0.88 -0.63 -0.41 -0.48 0.64 0.95 -1.22 -1.23 -0.63 -0.90 -0.82 0.29 -0.62 -0.54 0.67 -1.14
9564 || orf19.6399 || ATS1 || || Protein required for modification of wobble nucleosides in tRNA; induced upon adherence to polystyrene; regulated by Sef1, Sfu1, and Hap43 || 1 -1.31 -1.06 -0.36 -0.40 0.88 1.65 -1.77 -1.87 -0.61 -1.17 -1.21 -0.16 -0.63 -0.71 1.00 -1.04
9565 || orf19.338 || || || Putative glycoside hydrolase; stationary phase enriched protein; Hog1p-downregulated; shows colony morphology-related gene regulation by Ssn6p || 1 -0.42 -0.49 -0.25 -0.21 0.25 0.82 -0.68 -1.10 -0.48 -0.78 -0.63 -0.10 -0.22 -0.23 0.83 -0.47
9566 || orf19.338 || || || Putative glycoside hydrolase; stationary phase enriched protein; Hog1p-downregulated; shows colony morphology-related gene regulation by Ssn6p || 1 -0.73 -0.40 0.20 0.19 0.23 0.75 -0.80 -1.08 -0.37 -0.80 -0.61 0.10 -0.12 -0.16 0.56 -0.50
9567 || orf19.3362 || || || Has domain(s) with predicted flavin adenine dinucleotide binding, oxidoreductase activity and role in oxidation-reduction process || 1 -0.60 -0.48 -0.21 -0.21 0.65 0.74 -1.09 -1.17 -0.44 -1.42 -0.31 -0.30 -0.75 -0.47 0.58 -0.39
9568 || orf19.2241 || PST1 || || Putative 1,4-benzoquinone reductase; hyphal-induced; regulated by Cyr1, Ras1, Efg1, Nrg1, Rfg1, Tup1; Hap43-induced; Spider biofilm induced || 1 -0.56 -0.69 -0.10 -0.07 1.14 2.24 -1.80 -2.06 -1.21 -2.05 -1.64 -0.71 -0.81 -1.50 1.43 -2.15
9569 || orf19.2693 || GST2 || || Glutathione S transferase; induced by benomyl and in populations of cells exposed to fluconazole over multiple generations; regulated by Nrg1, Tup1; induced by nitric oxide; stationary phase enriched; Spider biofilm induced || 1 -0.06 -0.12 0.53 0.11 0.96 2.15 -1.60 -1.74 -1.22 -1.72 -1.95 -1.52 -1.28 -0.71 0.54 -1.14
9570 || orf19.2870 || || || Protein of unknown function; rat catheter and Spider biofilm induced || 1 -0.06 0.06 1.02 0.85 2.18 2.92 -2.61 -3.42 -2.13 -2.31 -2.28 -1.99 -2.72 -2.86 0.96 -2.25
9571 || orf19.2870 || || || Protein of unknown function; rat catheter and Spider biofilm induced || 1 -0.10 0.12 0.76 0.46 2.36 2.73 -2.68 -3.51 -1.99 -3.52 -2.62 -2.11 -2.32 -3.28 0.88 -2.09
9572 || orf19.4135 || PRC2 || || Putative carboxypeptidase; induced by human neutrophils; Spider biofilm induced || 1 -0.19 -0.26 0.46 0.47 0.43 1.28 -1.58 -2.41 -1.32 -2.03 -2.00 -0.65 -0.66 -1.29 0.68 -0.62
9573 || orf19.6592 || || || Predicted membrane transporter, member of the aromatic acid:proton symporter (AAHS) family, major facilitator superfamily (MFS) || 1 -0.62 -0.63 0.61 1.39 1.30 2.21 -2.64 -2.57 -1.69 -2.22 -3.06 -1.77 -0.94 -1.89 0.86
9574 || orf19.6592 || || || Predicted membrane transporter, member of the aromatic acid:proton symporter (AAHS) family, major facilitator superfamily (MFS) || 1 -0.45 -0.49 0.66 0.76 1.48 2.32 -2.14 -2.31 -1.31 -2.19 -2.07 -1.18 -0.99 -1.25 1.31 -0.95
9575 || orf19.673 || || || Has domain(s) with predicted FMN binding, oxidoreductase activity and role in oxidation-reduction process || 1 -0.55 -0.67 0.61 0.20 1.08 1.96 -1.32 -1.44 -1.25 -1.60 -1.25 -0.47 -0.40 -0.80 0.74 -0.42
9576 || orf19.673 || || || Has domain(s) with predicted FMN binding, oxidoreductase activity and role in oxidation-reduction process || 1 -0.80 -0.89 0.51 0.19 1.06 1.88 -1.91 -2.01 -1.37 -1.81 -1.47 -0.33 -0.62 -1.07 0.63 -0.97
9577 || orf19.3150 || GRE2 || || Putative reductase; Nrg1 and Tup1-regulated; benomyl- and hyphal-induced; macrophage/pseudohyphal-repressed; repressed by low iron; possibly involved in osmotic stress response; stationary phase enriched protein; Spider biofilm induced || 1 -0.44 -0.41 0.43 0.35 0.74 1.64 -1.16 -1.60 -1.18 -0.99 -1.25 -0.26 -1.32 -1.46 0.85 -0.36
9578 || orf19.1069 || RPN4 || || C2H2 transcription factor; putative regulator of proteasome genes; DNA recognition sequence (GAAGGCAAAA) enriched in regions upstream of proteasome genes; induced in core stress response; Hap43-induced; Spider biofilm induced || 1 -0.62 -0.72 0.16 -0.19 0.83 1.66 -1.60 -1.94 -0.70 -1.03 -1.15 -0.93 -1.32 -1.04 0.86 -0.56
9579 || orf19.733 || || || Ortholog(s) have endoplasmic reticulum localization || 1 -0.75 -0.93 -0.26 -0.09 0.76 1.75 -0.93 -1.38 -1.15 -2.02 -1.08 -1.14 -0.83 -0.86 0.33 -0.34
9580 || orf19.6117 || || || S. pombe ortholog SPAC5D6.04 is a predicted auxin family transmembrane transporter; ketoconazole and hypoxia induced || 1 -0.86 -0.95 -0.41 -0.11 1.06 1.93 -1.05 -1.68 -1.44 -2.17 -1.24 -1.33 -0.77 -0.82 0.69 -0.66
9581 || orf19.733 || || || Ortholog(s) have endoplasmic reticulum localization || 1 -1.02 -1.19 -0.24 -0.30 1.03 1.90 -1.13 -1.73 -1.06 -2.22 -1.21 -1.46 -0.89 -0.91 0.60 -0.72
9582 || orf19.6117 || || || S. pombe ortholog SPAC5D6.04 is a predicted auxin family transmembrane transporter; ketoconazole and hypoxia induced || 1 -1.12 -1.23 -0.28 -0.14 0.90 1.96 -0.98 -1.57 -1.10 -1.95 -1.30 -1.24 -1.11 -0.73 0.69 -0.54
9583 || orf19.6117 || || || S. pombe ortholog SPAC5D6.04 is a predicted auxin family transmembrane transporter; ketoconazole and hypoxia induced || 1 -1.03 -1.21 -0.40 -0.01 1.03 1.95 -1.25 -1.91 -1.32 -2.05 -1.41 -1.25 -0.96 -0.91 0.59 -0.36
9584 || orf19.6117 || || || S. pombe ortholog SPAC5D6.04 is a predicted auxin family transmembrane transporter; ketoconazole and hypoxia induced || 1 -1.34 -1.41 -0.76 -0.58 0.86 1.56 -1.55 -2.09 -1.60 -2.24 -1.51 -1.41 -1.31 -0.99 0.38 -0.72
9585 || orf19.4347 || || || Putative serine/threonine protein kinase; Hog1p-induced || 1 -0.93 -0.88 -0.28 0.02 0.77 1.18 -1.11 -1.67 -1.35 -1.47 -0.64 -0.50 -0.93 -0.64 0.48 -0.38
9586 || orf19.6489 || FMP45 || || Predicted membrane protein induced during mating; mutation confers hypersensitivity to toxic ergosterol analog, to amphotericin B; alkaline repressed; repressed by alpha pheromone in SpiderM medium; rat catheter, Spider biofilm induced || 1 -2.16 -2.34 -1.33 -1.65 1.11 2.80 -3.11 -3.86 -3.21 -4.12 -2.79 -1.23 -1.98 -3.85 1.49 -1.81
9587 || orf19.3369 || MOH1 || || Ortholog of S. cerevisiae Moh1, essential for staionary phase growth; induced by alpha pheromone in SpiderM medium and by Mnl1 under weak acid stress; possibly essential (UAU1 method); flow model biofilm induced; Spider biofilm induced || 1 -0.92 -0.90 -0.59 -0.32 0.86 1.71 -2.36 -3.07 -1.97 -2.92 -2.43 -1.93 -1.82 -2.67 1.21 -1.42
9588 || orf19.3369 || MOH1 || || Ortholog of S. cerevisiae Moh1, essential for staionary phase growth; induced by alpha pheromone in SpiderM medium and by Mnl1 under weak acid stress; possibly essential (UAU1 method); flow model biofilm induced; Spider biofilm induced || 1 -0.83 -0.71 -0.46 -0.25 1.03 1.79 -2.29 -2.82 -1.84 -2.70 -2.43 -1.93 -1.84 -2.17 1.16 -1.39
9589 || orf19.3369 || MOH1 || || Ortholog of S. cerevisiae Moh1, essential for staionary phase growth; induced by alpha pheromone in SpiderM medium and by Mnl1 under weak acid stress; possibly essential (UAU1 method); flow model biofilm induced; Spider biofilm induced || 1 -0.82 -0.69 -0.60 -0.17 0.99 1.66 -2.18 -2.82 -1.67 -2.92 -2.42 -1.91 -1.51 -2.20 1.31 -1.32
9590 || orf19.3369 || MOH1 || || Ortholog of S. cerevisiae Moh1, essential for staionary phase growth; induced by alpha pheromone in SpiderM medium and by Mnl1 under weak acid stress; possibly essential (UAU1 method); flow model biofilm induced; Spider biofilm induced || 1 -0.86 -0.92 -0.44 -0.34 0.95 1.74 -2.32 -2.71 -1.75 -2.94 -2.38 -1.72 -1.75 -1.95 1.36 -1.54
9591 || orf19.3369 || MOH1 || || Ortholog of S. cerevisiae Moh1, essential for staionary phase growth; induced by alpha pheromone in SpiderM medium and by Mnl1 under weak acid stress; possibly essential (UAU1 method); flow model biofilm induced; Spider biofilm induced || 1 -0.82 -0.74 -0.28 0.06 1.01 1.91 -2.34 -2.71 -1.66 -2.99 -2.36 -1.85 -1.53 -2.09 1.25 -1.37
9592 || orf19.1785 || || || Protein with a PI31 proteasome regulator domain; Hap43-repressed; flow model biofilm induced || 1 -0.78 -0.73 0.06 -0.20 1.45 1.81 -2.26 -2.38 -1.37 -2.41 -1.74 -1.09 -1.53 -1.76 0.36 -1.14
9593 || orf19.673 || || || Has domain(s) with predicted FMN binding, oxidoreductase activity and role in oxidation-reduction process || 1 -0.88 -0.96 0.17 -0.31 0.68 1.68 -2.04 -2.42 -1.11 -2.24 -1.77 -1.07 -0.93 -1.40 0.49 -0.68
9594 || orf19.2608 || ADH5 || || Putative alcohol dehydrogenase; regulated by white-opaque switch; fluconazole-induced; antigenic in murine infection; regulated by Nrg1, Tup1; Hap43, macrophage repressed, flow model biofilm induced; Spider biofilm induced || 1 -1.19 -1.08 0.11 -1.14 -1.95 -2.71 -1.17 -2.87 -2.38 -0.93 -0.92 -1.47 1.23 -0.36
9595 || orf19.2608 || ADH5 || || Putative alcohol dehydrogenase; regulated by white-opaque switch; fluconazole-induced; antigenic in murine infection; regulated by Nrg1, Tup1; Hap43, macrophage repressed, flow model biofilm induced; Spider biofilm induced || 1 -1.36 -1.26 -0.09 -1.37 -2.18 -2.94 -1.34 -3.05 -2.52 -1.18 -1.33 -1.62 1.25 -0.53
9596 || orf19.1785 || || || Protein with a PI31 proteasome regulator domain; Hap43-repressed; flow model biofilm induced || 1 -0.60 -0.51 -0.01 -0.51 1.87 2.00 -1.94 -2.21 -1.19 -2.14 -1.51 -0.71 -1.06 -1.27 0.69 -0.68
9597 || orf19.4791 || || || Protein of unknown function; Spider biofilm induced || 1 -0.69 -0.78 -0.22 -0.34 1.15 2.15 -1.82 -2.24 -0.97 -1.91 -2.24 -0.57 -1.06 -1.70 0.68 -1.01
9598 || orf19.4791 || || || Protein of unknown function; Spider biofilm induced || 1 -1.03 -1.08 -0.65 -1.00 1.05 1.92 -2.22 -2.93 -1.65 -1.89 -2.56 -0.50 -1.76 -1.72 0.69 -0.68
9599 || orf19.4132 || || || Protein of unknown function; UPF0057 protein family member; localizes to the plasma membrane; Spider biofilm induced || 1 -0.47 -0.56 0.16 -0.05 0.60 1.02 -1.59 -2.21 -1.24 -2.32 -0.85 -0.55 -0.73 -1.81 0.41 -0.70
9600 || orf19.2849 || AQY1 || || Aquaporin water channel; osmotic shock resistance, WT freeze tolerance; virulent in mice; flucytosine repressed; flow model/RPMI/Spider/rat catheter biofilm induced; required for RPMI biofilm formation; Bcr1-induced in a/a RPMI biofilms || 1 -1.25 -1.36 -0.17 -1.01 0.49 2.27 -3.11 -3.90 -3.38 -4.83 -1.90 -0.80 -0.75 -2.79 1.85 -0.50
9601 || orf19.2849 || AQY1 || || Aquaporin water channel; osmotic shock resistance, WT freeze tolerance; virulent in mice; flucytosine repressed; flow model/RPMI/Spider/rat catheter biofilm induced; required for RPMI biofilm formation; Bcr1-induced in a/a RPMI biofilms || 1 -1.63 -1.66 -0.02 -0.77 -0.01 2.24 -3.56 -4.41 -3.58 -5.04 -2.47 -0.97 -0.95 -2.62 1.65 -0.79
9602 || orf19.1368 || || || Protein of unknown function; flow model biofilm induced; Spider biofilm induced || 1 -0.72 -0.65 -0.29 -0.42 0.20 0.82 -2.20 -2.65 -1.96 -2.79 -1.40 -0.34 -0.36 -1.64 -0.18 -1.13
9603 || orf19.251 || GLX3 || || Glutathione-independent glyoxalase; binds human immunoglobulin E; alkaline, fluconazole, Hog1 repressed; hypoxia, oxidative stress via Cap1, Hap43 induced; stationary-phase enriched; rat catheter, Spider biofilm induced || 1 -0.64 -0.52 -0.27 -0.45 -3.48 -3.37 -2.63 -2.59 -1.69 -0.55 -0.19 -1.69 1.70 -1.52
9604 || orf19.251 || GLX3 || || Glutathione-independent glyoxalase; binds human immunoglobulin E; alkaline, fluconazole, Hog1 repressed; hypoxia, oxidative stress via Cap1, Hap43 induced; stationary-phase enriched; rat catheter, Spider biofilm induced || 1 -0.59 -0.64 -0.36 -0.50 -3.41 -3.33 -2.58 -2.81 -1.61 -0.83 -0.20 -2.00 1.69 -1.88
9605 || orf19.2241 || PST1 || || Putative 1,4-benzoquinone reductase; hyphal-induced; regulated by Cyr1, Ras1, Efg1, Nrg1, Rfg1, Tup1; Hap43-induced; Spider biofilm induced || 1 -0.98 -1.02 -0.56 -0.50 1.43 2.38 -3.34 -3.80 -2.44 -2.69 -1.75 -0.76 -1.16 -2.50 1.20 -1.76
9606 || orf19.2241 || PST1 || || Putative 1,4-benzoquinone reductase; hyphal-induced; regulated by Cyr1, Ras1, Efg1, Nrg1, Rfg1, Tup1; Hap43-induced; Spider biofilm induced || 1 -0.84 -0.94 -0.60 -0.88 1.56 2.52 -2.82 -3.51 -2.45 -3.35 -1.38 -0.72 -1.07 -3.25 1.48 -1.78
9607 || orf19.2241 || PST1 || || Putative 1,4-benzoquinone reductase; hyphal-induced; regulated by Cyr1, Ras1, Efg1, Nrg1, Rfg1, Tup1; Hap43-induced; Spider biofilm induced || 1 -0.59 -0.80 -0.51 -0.73 1.19 2.60 -2.50 -3.05 -2.15 -2.81 -1.61 -0.69 -1.01 -2.98 1.50 -2.00
9608 || orf19.4470 || || || Protein of unknown function; Hap43-repressed gene || 1 -0.39 -0.40 -0.53 -0.25 0.42 0.83 -1.32 -1.39 -1.27 -0.68 -0.92 -0.72 -0.39 -1.01 0.60 -0.72
9609 || orf19.3335 || || || Plasma membrane protein of unknown function; colony morphology-related gene regulation by Ssn6; repressed by nitric oxide || 1 -0.19 -0.31 -0.64 -0.81 0.39 0.87 -0.97 -1.22 -1.31 -1.04 -0.69 -0.38 -0.55 -1.13 1.01 -0.68
9610 || orf19.3335 || || || Plasma membrane protein of unknown function; colony morphology-related gene regulation by Ssn6; repressed by nitric oxide || 1 -0.18 -0.21 -0.34 -0.28 0.15 0.74 -1.11 -1.12 -1.41 -1.17 -0.77 -0.17 -0.74 -1.06 0.93 -0.80
9611 || orf19.4526 || HSP30 || || Putative heat shock protein; fluconazole repressed; amphotericin B induced; Spider biofilm induced; rat catheter biofilm induced || 1 -2.12 -2.09 -1.88 -2.38 -6.20 -8.38 -6.22 -7.13 -7.93 -7.25 -2.90 -6.68 0.76 -7.51
9612 || orf19.4526 || HSP30 || || Putative heat shock protein; fluconazole repressed; amphotericin B induced; Spider biofilm induced; rat catheter biofilm induced || 1 -1.62 -1.66 -1.32 -2.18 -5.07 -6.52 -5.27 -6.32 -6.30 -6.03 -2.66 -6.49 1.32 -6.33
9613 || orf19.4526 || HSP30 || || Putative heat shock protein; fluconazole repressed; amphotericin B induced; Spider biofilm induced; rat catheter biofilm induced || 1 -1.31 -1.26 -0.17 -1.11 -4.00 -4.88 -3.89 -4.81 -5.30 -4.98 -2.20 -4.83 1.33 -4.76
9614 || orf19.7283 || || || Protein of unknown function; rat catheter and Spider biofilm induced || 1 -1.20 -1.00 -0.22 -0.80 2.37 2.79 -1.65 -3.03 -0.96 -2.74 -3.77 -2.42 -2.31 -3.38 -0.10 -2.99
9615 || orf19.7283 || || || Protein of unknown function; rat catheter and Spider biofilm induced || 1 -0.94 -0.87 -0.45 -1.75 2.84 3.12 -1.27 -3.04 -0.66 -3.43 -4.30 -2.66 -2.34 -3.28 0.59 -3.52
9616 || orf19.7283 || || || Protein of unknown function; rat catheter and Spider biofilm induced || 1 -1.18 -0.97 -0.43 -1.80 2.54 2.88 -1.46 -3.35 -0.81 -3.96 -4.32 -2.79 -2.85 -3.30 0.42 -3.01
9617 || orf19.3612 || PST2 || || Putative NADH:quinone oxidoreductase; similar to 1,4-benzoquinone reductase; immunogenic in mice; induced by benomyl, oxidative stress via Cap1; fungal-specific; farnesol-repressed; Spider biofilm induced || 1 -0.34 -0.23 0.45 0.49 0.71 1.68 -0.86 -1.15 -0.25 -0.98 -1.75 -0.97 -0.17 -0.49 0.92 -1.84
9618 || orf19.2515 || || || ZZ-type zinc finger protein; rat catheter and Spider biofilm induced || 1 -0.81 -0.78 0.40 0.53 0.77 1.84 -1.70 -1.98 -0.43 -1.39 -3.08 -1.04 -0.72 -0.42 1.22 -1.76
9619 || orf19.2515 || || || ZZ-type zinc finger protein; rat catheter and Spider biofilm induced || 1 -0.77 -0.79 0.32 0.22 0.88 1.57 -1.78 -2.00 -0.59 -1.43 -3.04 -1.24 -0.62 -0.61 1.06 -1.94
9620 || orf19.7385 || || || CCCH zinc finger protein; Spider biofilm induced || 1 -0.70 -0.61 0.73 0.51 1.34 2.44 -1.74 -2.69 -0.52 -1.99 -4.02 -2.20 -0.44 -1.65 1.36 -1.72
9621 || orf19.7385 || || || CCCH zinc finger protein; Spider biofilm induced || 1 -0.63 -0.65 0.29 0.45 1.39 2.21 -1.56 -2.58 -0.56 -2.38 -3.95 -2.08 -0.22 -2.55 1.41 -2.38
9622 || orf19.4970 || || || Protein of unknown function; Spider biofilm induced || 1 -1.29 -1.40 -0.46 -0.85 0.71 1.94 -3.79 -4.09 -1.93 -2.36 -5.56 -2.85 -1.56 -1.88 0.50 -2.53
9623 || orf19.4970 || || || Protein of unknown function; Spider biofilm induced || 1 -1.34 -1.47 -0.34 -0.64 0.91 2.42 -3.81 -4.93 -1.91 -2.44 -5.44 -2.69 -1.55 -1.95 0.70 -1.71
9624 || orf19.419 || || || Protein of unknown function; flow model biofilm induced; Spider biofilm induced || 1 -1.04 -1.12 -0.29 -0.07 0.69 0.83 -1.93 -2.52 -1.33 -2.19 -2.56 -1.44 -1.14 -0.81 0.28 -1.29
9625 || orf19.6850 || || || Putative transcription factor with C3HC4 zinc finger DNA-binding motif; mutants are viable || 1 -0.26 -0.45 0.38 0.11 0.38 0.47 -1.07 -1.04 -0.36 -1.04 -1.07 -0.37 -0.80 -0.76 -0.21 -0.27
9626 || orf19.999 || GCA2 || || Predicted extracellular glucoamylase; induced by ketoconazole; possibly essential, disruptants not obtained by UAU1 method; promotes biofilm matrix formation; Spider biofilm induced; Bcr1-induced in RPMI a/a biofilms || 1 -0.87 -0.82 0.94 0.63 0.50 1.24 -1.57 -1.85 -0.20 -0.80 -3.15 -1.93 -1.35 -1.12 0.32 -1.47
9627 || orf19.4899 || GCA1 || || Extracellular/plasma membrane-associated glucoamylase; expressed in rat oral infection; regulated by carbohydrates, pH, galactose; promotes biofilm matrix formation; flow model biofilm induced; Bcr1 repressed in RPMI a/a biofilms || 1 -0.59 -0.75 1.10 0.58 0.57 1.36 -1.05 -1.34 -0.33 -1.05 -1.72 -1.17 -1.03 -0.64 0.52 -0.87
9628 || orf19.3351 || || || Protein of unknown function; Hap43-induced; Spider biofilm induced || 1 -0.34 -0.45 0.82 0.79 0.58 1.40 -1.78 -1.95 -0.68 -1.63 -2.14 -0.53 -0.99 -0.51 0.21 -0.62
9629 || orf19.419 || || || Protein of unknown function; flow model biofilm induced; Spider biofilm induced || 1 -1.09 -1.16 0.47 0.62 0.76 1.53 -2.35 -2.78 -1.08 -1.65 -2.84 -0.93 -1.13 -0.14 0.26 -0.85
9630 || orf19.5986 || THI4 || || Thiamine biosynthetic enzyme precursor; repressed during the mating process; stationary phase enriched protein; Spider biofilm induced || 1 -1.05 -0.79 0.69 0.65 0.80 0.91 -1.90 -2.28 -0.30 -1.07 -3.25 -1.73 -1.41 -0.50 -0.57 -0.96
9631 || orf19.5986 || THI4 || || Thiamine biosynthetic enzyme precursor; repressed during the mating process; stationary phase enriched protein; Spider biofilm induced || 1 -0.77 -0.91 0.52 0.61 0.51 0.81 -1.70 -1.59 -0.74 -1.03 -1.90 -1.12 -0.92 -0.36 -0.81 -0.71
9632 || orf19.5986 || THI4 || || Thiamine biosynthetic enzyme precursor; repressed during the mating process; stationary phase enriched protein; Spider biofilm induced || 1 -0.88 -0.79 0.17 0.35 0.25 0.44 -1.53 -1.38 -0.99 -1.16 -1.71 -0.85 -1.16 -0.81 -0.51 -0.80
9633 || orf19.1779 || MP65 || || Cell surface mannoprotein; cell-wall glucan metabolism, adhesion; adhesin motif; O-glycosylation; induced by heat, germ tube formation, wall regeneration; mycelial antigen; diagnostic marker; fluconazole-repressed; Spider biofilm induced || 1 -0.44 -0.49 -0.06 0.54 0.46 0.55 -0.99 -1.04 -0.38 -0.36 -1.10 -0.78 -0.77 -0.87 -0.46 -0.71
9634 || orf19.1779 || MP65 || || Cell surface mannoprotein; cell-wall glucan metabolism, adhesion; adhesin motif; O-glycosylation; induced by heat, germ tube formation, wall regeneration; mycelial antigen; diagnostic marker; fluconazole-repressed; Spider biofilm induced || 1 -0.39 -0.53 0.25 0.46 -1.05 -1.00 -0.22 -0.36 -1.24 -0.51 -0.80 -0.56 -0.28 -0.49
9635 || orf19.1779 || MP65 || || Cell surface mannoprotein; cell-wall glucan metabolism, adhesion; adhesin motif; O-glycosylation; induced by heat, germ tube formation, wall regeneration; mycelial antigen; diagnostic marker; fluconazole-repressed; Spider biofilm induced || 1 -0.29 -0.38 0.52 -0.98 -0.91 -0.18 -0.25 -1.19 -0.44 -0.64 -0.43 -0.19 -0.53
9636 || orf19.1779 || MP65 || || Cell surface mannoprotein; cell-wall glucan metabolism, adhesion; adhesin motif; O-glycosylation; induced by heat, germ tube formation, wall regeneration; mycelial antigen; diagnostic marker; fluconazole-repressed; Spider biofilm induced || 1 -0.20 -0.28 0.35 0.85 0.76 0.75 -0.89 -0.86 -0.21 -0.27 -1.01 -0.55 -0.53 -0.63 -0.23 -0.59
9637 || orf19.5412 || || || Ortholog of S. cerevisiae : ECM9, C. glabrata CBS138 : CAGL0L02255g, C. dubliniensis CD36 : Cd36_80470, C. parapsilosis CDC317 : CPAR2_503390 and Candida tenuis NRRL Y-1498 : CANTEDRAFT_133107 || 1 -0.33 -0.46 0.10 0.06 0.55 0.38 -0.40 -0.58 -0.38 -0.15 -0.37 -0.05 -0.35 -0.26 0.04 0.05
9638 || orf19.4543 || UGA2 || || Predicted succinate semialdehyde dehydrogenase; predicted role in glutamate catabolism; transcription regulated by Mig1, Tup1, Gcn4; mutants are viable || 1 -0.52 -0.80 0.15 0.41 0.90 1.23 -0.95 -1.24 -0.41 -0.74 -1.15 -0.12 -0.82 -1.02 0.34 -0.37
9639 || orf19.6760 || MDS3 || || TOR signaling pathway component; required for growth and hyphal formation at alkaline pH, for full virulence in a mouse model of systemic infection and for SD and Spider medium biofilm formation; role in chlamydospore formation || 1 -0.57 -0.46 0.10 0.11 0.74 0.66 -0.58 -0.75 -0.58 -0.63 -0.31 -0.20 -0.35 -0.86 0.33 -0.13
9640 || orf19.4448 || SOG2 || || Leucine-rich-repeat domain protein of RAM cell wall integrity signaling network; role in cell separation, azole sensitivity; required for hyphal growth; lacks orthologs in higher eukaryotes || 1 -0.17 -0.20 0.03 -0.21 0.53 0.34 -0.41 -0.40 -0.19 -0.24 -0.28 -0.09 -0.37 -0.46 0.16 -0.23
9641 || orf19.6137 || || || Ortholog of C. dubliniensis CD36 : Cd36_32940, Candida tenuis NRRL Y-1498 : CANTEDRAFT_134955, Debaryomyces hansenii CBS767 : DEHA2E04422g and Pichia stipitis Pignal : PICST_33357 || 1 -0.21 -0.28 -0.10 -0.39 0.41 0.19 -0.41 -0.54 -0.34 -0.30 -0.50 -0.35 -0.34 -0.23 -0.26 -0.24
9642 || orf19.1976 || TRX2 || || Similar to thioredoxins; not expected to be enzymatically active because it lacks a canonical thioredoxin active site (Trp-Cys-Gly-Pro-Cys); TRX1 encodes all of the cytoplasmic/nuclear thioredoxin function in C. albicans; Hap43p-induced || 1 -2.07 -1.95 -1.36 -1.46 2.17 2.47 -2.59 -2.82 -2.09 -2.32 -2.73 -1.98 -2.20 -1.61 -1.30 -2.23
9643 || orf19.1976 || TRX2 || || Similar to thioredoxins; not expected to be enzymatically active because it lacks a canonical thioredoxin active site (Trp-Cys-Gly-Pro-Cys); TRX1 encodes all of the cytoplasmic/nuclear thioredoxin function in C. albicans; Hap43p-induced || 1 -1.34 -1.35 -1.05 -1.24 1.93 2.29 -2.17 -2.48 -1.72 -2.51 -2.65 -2.12 -1.80 -1.55 -1.13 -1.78
9644 || orf19.1976 || TRX2 || || Similar to thioredoxins; not expected to be enzymatically active because it lacks a canonical thioredoxin active site (Trp-Cys-Gly-Pro-Cys); TRX1 encodes all of the cytoplasmic/nuclear thioredoxin function in C. albicans; Hap43p-induced || 1 -1.57 -1.63 -0.57 -0.87 1.77 2.16 -1.97 -2.17 -1.20 -2.36 -2.38 -1.87 -1.90 -1.58 -1.07 -1.42
9645 || orf19.1976 || TRX2 || || Similar to thioredoxins; not expected to be enzymatically active because it lacks a canonical thioredoxin active site (Trp-Cys-Gly-Pro-Cys); TRX1 encodes all of the cytoplasmic/nuclear thioredoxin function in C. albicans; Hap43p-induced || 1 -1.43 -1.58 0.11 0.20 1.94 2.32 -1.88 -1.80 -1.43 -2.12 -2.55 -1.70 -1.88 -1.66 -1.20 -1.74
9646 || orf19.1976 || TRX2 || || Similar to thioredoxins; not expected to be enzymatically active because it lacks a canonical thioredoxin active site (Trp-Cys-Gly-Pro-Cys); TRX1 encodes all of the cytoplasmic/nuclear thioredoxin function in C. albicans; Hap43p-induced || 1 -0.55 -1.74 -0.33 -0.40 1.99 2.30 -1.95 -1.95 -0.64 -2.24 -2.62 -1.85 -1.89 -1.63 -1.22 -1.96
9647 || orf19.7068 || MAC1 || || Copper fist transcription factor; regulator of CTR1 copper transporter; induces CTR1 in low-copper conditions; ectopic expression causes copper-sensitive stimulation of filamentation in S. cerevisiae; Spider biofilm induced || 1 -0.46 -0.46 -0.16 -0.37 0.57 1.28 -0.42 -0.56 -0.44 -0.67 -1.08 -0.64 -0.28 -0.22 -0.16 -0.44
9648 || orf19.7068 || MAC1 || || Copper fist transcription factor; regulator of CTR1 copper transporter; induces CTR1 in low-copper conditions; ectopic expression causes copper-sensitive stimulation of filamentation in S. cerevisiae; Spider biofilm induced || 1 -0.44 -0.27 -0.04 -0.08 0.35 1.33 -0.63 -0.35 -0.23 -0.42 -0.85 -0.37 -0.33 -0.57 -0.12 -0.22
9649 || orf19.6722 || || || Protein similar to S. cerevisiae Rad4p; down-regulation associated with azole resistance || 1 -0.34 -0.19 0.17 0.05 0.40 1.11 -0.77 -0.71 -0.41 -0.49 -0.76 -0.31 -0.20 -0.17 -0.10 -0.48
9650 || orf19.5364 || || || Putative pre-mRNA splicing factor; intron in 5'-UTR; possibly an essential gene, disruptants not obtained by UAU1 method || 1 -0.28 -0.28 -0.02 -0.07 0.89 1.33 -0.74 -0.85 -0.73 -0.12 -0.77 -0.65 -0.49 -0.19 -0.38 -0.32
9651 || orf19.970 || || || Protein with a predicted role in microtubule-related processes; Spider biofilm induced || 1 0.10 -0.06 0.03 -0.32 0.69 1.20 -0.29 -0.48 -0.81 -0.63 -0.69 -0.75 -0.50 -0.92 -0.09 -0.28
9652 || orf19.2114 || || || Predicted uricase; ortholog of S. pombe SPCC1223.09; Spider biofilm induced || 1 -0.17 0.01 0.25 0.07 0.80 2.00 -0.64 -0.93 -1.14 -1.25 -1.92 -1.36 -0.70 -1.13 0.52 -0.64
9653 || orf19.2114 || || || Predicted uricase; ortholog of S. pombe SPCC1223.09; Spider biofilm induced || 1 0.10 0.23 0.13 -0.02 1.38 2.03 -0.58 -1.07 -0.97 -1.43 -1.41 -1.53 -0.29 -1.37 0.92 -0.88
9654 || orf19.1764 || || || Protein of unknown function; rat catheter and Spider biofilm induced || 1 0.26 0.35 -0.14 -0.14 1.03 0.89 -0.68 -1.00 -0.74 -0.78 -0.97 -0.78 -0.25 -0.75 0.61 -0.41
9655 || orf19.3973 || || || Ortholog of Hua1, a zinc finger domain protein with sequence similarity to Type I J-proteins; flow model biofilm induced || 1 0.08 -0.20 -0.01 0.00 0.88 0.86 -0.36 -0.38 -0.41 -0.92 -0.51 -0.39 -0.34 -0.57 0.79 -0.08
9656 || orf19.3973 || || || Ortholog of Hua1, a zinc finger domain protein with sequence similarity to Type I J-proteins; flow model biofilm induced || 1 -0.23 -0.22 -0.26 -0.13 0.91 0.82 -0.52 -0.61 -0.44 -1.19 -0.56 -0.60 -0.42 -0.54 0.56 -0.40
9657 || orf19.11 || || || Protein of unknown function; transcript regulated by Mig1 and Tup1; rat catheter biofilm induced || 1 -0.45 -0.53 -0.12 -0.96 1.86 2.51 -1.15 -1.60 -0.66 -2.19 -1.37 -1.62 0.52 -1.13 1.05 -0.65
9658 || orf19.2620 || || || Ortholog of C. dubliniensis CD36 : Cd36_33120 and Candida albicans WO-1 : CAWG_02046 || 1 -0.54 -0.53 -0.11 -1.16 1.96 2.48 -0.97 -1.36 -0.84 -2.03 -1.83 -1.86 -0.33 -1.08 1.22 -0.21
9659 || orf19.11 || || || Protein of unknown function; transcript regulated by Mig1 and Tup1; rat catheter biofilm induced || 1 -1.16 -0.82 -0.81 -2.02 2.24 2.60 -2.17 -2.46 -0.88 -2.35 -3.12 -2.52 -0.23 -1.43 1.23 -1.69
9660 || orf19.7342 || AXL1 || || Putative endoprotease; induced by alpha factor; transcript is upregulated in an RHE model of oral candidiasis and in clinical isolates from HIV+ patients with oral candidiasis || 1 0.36 0.05 -0.55 -0.49 1.31 1.32 -0.70 -0.73 -1.19 -1.23 -0.97 -0.80 0.12 -0.25 0.84 -0.40
9661 || orf19.559 || FGR14 || || Protein encoded in retrotransposon Zorro3 with similarity to retroviral endonuclease-reverse transcriptase proteins; lacks an ortholog in S. cerevisiae; transposon mutation affects filamentous growth || 1 0.02 -0.02 -0.06 0.13 0.73 0.49 -0.39 -0.51 -0.36 -0.45 -0.93 -0.64 -0.10 -0.19 0.45 -0.50
9662 || orf19.2177 || || || Sef1p-, Sfu1p-, and Hap43p-regulated gene; overlaps IFM3/orf19.2176 || 1 -0.27 -0.08 -0.47 -0.29 1.37 1.10 -1.57 -1.00 -1.15 -1.87 -0.86 -1.19 -0.73 -1.25 -0.32 -0.75
9663 || orf19.5865 || || || Ortholog(s) have RNA-dependent ATPase activity, role in generation of catalytic spliceosome for first transesterification step and U2-type catalytic step 1 spliceosome localization || 1 0.26 0.30 -0.17 -0.56 0.64 0.70 -0.54 -0.72 -0.66 -0.61 -0.46 -0.73 -0.34 -0.91 -0.15 -0.37
9664 || orf19.2315 || || || Putative transcription factor with bZIP DNA-binding motif || 1 -0.19 -0.34 -0.46 -0.73 0.55 0.54 -0.55 -1.16 -0.98 -0.76 -0.45 -0.17 0.29 -0.45 0.60 -0.49
9665 || orf19.2315 || || || Putative transcription factor with bZIP DNA-binding motif || 1 -0.25 -0.35 -0.11 -0.48 0.43 0.39 -0.67 -1.01 -0.69 -0.77 -0.46 -0.17 0.09 -0.68 0.50 -0.20
9666 || orf19.6555 || || || Ortholog(s) have zinc ion binding activity, role in protein import into mitochondrial intermembrane space and cytosol, mitochondrial intermembrane space, nucleus localization || 1 -0.50 -0.53 -0.51 -0.45 -0.02 0.75 -0.75 -1.82 -1.27 -1.22 -0.46 -0.42 -0.17 -0.74 0.47 0.34
9667 || orf19.215 || || || Component of a complex containing the Tor2p kinase; possible a role in regulation of cell growth; Spider biofilm induced || 1 -0.60 -0.39 -0.52 0.14 0.36 1.04 -0.44 -1.96 -1.55 -1.32 -0.71 -0.02 -0.61 -0.73 0.81 -0.12
9668 || orf19.2748 || ARG83 || || GAL4-like Zn(II)2Cys6 transcription factor; clade-associated expression; null shows abnormal regulation of invasive colony growth, is unable to utilize proline as a nitrogen source; flow model biofilm induced || 1 -0.82 -0.74 -0.87 -0.26 0.26 0.58 -0.88 -1.47 -0.60 -0.50 -1.13 -0.20 -0.21 -0.46 -0.31 -0.32
9669 || orf19.7054 || || || Dubious open reading frame || 1 -1.51 -1.37 -1.41 -1.10 0.02 0.85 -1.67 -2.31 -1.54 -1.29 -2.11 -0.76 -0.31 -0.99 -0.79 -0.01
9670 || orf19.3694 || || || Ortholog of C. dubliniensis CD36 : Cd36_02210, C. parapsilosis CDC317 : CPAR2_106350, Candida tenuis NRRL Y-1498 : CANTEDRAFT_116785 and Debaryomyces hansenii CBS767 : DEHA2C01980g || 1 -0.60 -0.48 -0.94 -0.35 0.12 0.44 -0.93 -1.52 -1.11 -0.60 -1.12 -0.50 0.30 -0.32 0.03 -0.14
9671 || orf19.6354 || || || Ortholog of C. dubliniensis CD36 : Cd36_11870, C. parapsilosis CDC317 : CPAR2_201650, Candida tenuis NRRL Y-1498 : cten_CGOB_00224 and Debaryomyces hansenii CBS767 : DEHA2D04884g || 1 -0.75 -0.60 -0.95 -0.55 -0.18 0.08 -0.86 -1.31 -1.26 -0.89 -0.76 -0.71 0.01 -0.76 -0.26 -0.07
9672 || orf19.3571 || || || Ortholog of C. dubliniensis CD36 : Cd36_19870, C. parapsilosis CDC317 : CPAR2_209420, Candida tenuis NRRL Y-1498 : CANTEDRAFT_100922 and Debaryomyces hansenii CBS767 : DEHA2D11176g || 1 -0.63 -0.44 -1.23 -1.02 -0.31 0.27 -0.99 -1.75 -1.17 -1.21 -1.33 -1.04 0.49 -0.46 -0.99 -0.43
9673 || orf19.6347 || || || Pre-mRNA splicing factor; important for catalytic step II of pre-mRNA splicing; possible role in cell cycle progression; Spider biofilm induced || 1 -0.46 -0.44 -1.26 -0.73 0.17 0.01 -0.84 -1.40 -1.09 -0.70 -1.16 -0.85 0.53 -0.56 -0.12 -0.85
9674 || orf19.5306 || || || Ortholog of C. dubliniensis CD36 : Cd36_43820 and Candida albicans WO-1 : CAWG_03393 || 1 -0.23 -0.18 -1.65 -1.14 1.51 0.44 -1.31 -2.28 -2.49 -1.51 -1.74 -2.67 0.90 -0.89 0.18 -0.82
9675 || orf19.147 || YAK1 || || Predicted serine-threonine protein kinase; involved in hyphal growth regulation and biofilm formation; flow model biofilm induced; induced in core caspofungin response || 1 -0.16 -0.09 -0.47 0.16 0.20 0.38 -0.69 -1.36 -0.85 -0.78 -1.13 -0.72 0.42 -0.37 0.05 -0.53
9676 || orf19.3204 || || || Ortholog of C. dubliniensis CD36 : Cd36_51610, C. parapsilosis CDC317 : CPAR2_303630, Candida tenuis NRRL Y-1498 : CANTEDRAFT_135125 and Debaryomyces hansenii CBS767 : DEHA2E19030g || 1 -0.25 -0.23 -0.63 -0.20 0.26 0.27 -0.78 -1.25 -0.70 -0.49 -0.86 -0.76 0.35 -0.51 0.16 -0.38
9677 || orf19.746 || || || Has domain(s) with predicted role in protein transport || 1 -0.29 -0.20 -0.85 -0.25 0.08 0.35 -0.70 -1.38 -1.18 -0.98 -0.59 -0.96 0.19 -0.50 0.45 -0.24
9678 || orf19.746 || || || Has domain(s) with predicted role in protein transport || 1 -0.37 -0.24 -0.92 -0.29 0.09 0.23 -0.71 -1.37 -1.12 -0.88 -0.78 -0.86 0.22 -0.64 0.32 -0.25
9679 || orf19.746 || || || Has domain(s) with predicted role in protein transport || 1 -0.45 -0.40 -0.92 -0.39 -0.14 0.18 -0.70 -1.37 -1.27 -0.94 -0.76 -0.89 0.19 -0.76 0.40 -0.17
9680 || orf19.746 || || || Has domain(s) with predicted role in protein transport || 1 -0.41 -0.57 -0.86 -0.35 -0.16 0.05 -0.74 -1.39 -1.19 -0.87 -0.60 -1.07 0.10 -0.82 0.21 -0.58
9681 || orf19.5289 || || || Dubious open reading frame || 1 -0.85 -1.00 -1.53 -0.74 0.66 0.88 -1.22 -1.92 -2.15 -1.71 -1.82 -1.48 0.05 -1.45 0.03 -0.71
9682 || orf19.5289 || || || Dubious open reading frame || 1 -0.81 -0.79 -1.76 -0.66 1.12 1.19 -1.08 -1.92 -1.91 -2.14 -1.75 -1.43 0.41 -1.60 0.36 -0.38
9683 || orf19.5289 || || || Dubious open reading frame || 1 -0.78 -0.77 -1.67 -0.70 0.97 1.21 -1.08 -2.01 -2.13 -2.17 -1.65 -1.66 0.28 -1.31 0.41 -0.51
9684 || orf19.5289 || || || Dubious open reading frame || 1 -0.77 -0.76 -1.56 -0.76 1.00 1.03 -1.08 -2.05 -2.05 -2.13 -1.69 -1.46 0.28 -1.34 0.30 -0.27
9685 || orf19.5289 || || || Dubious open reading frame || 1 -0.70 -0.70 -1.64 -0.73 1.09 1.23 -1.11 -1.95 -2.01 -2.41 -1.57 -1.30 0.36 -1.28 0.37 -0.31
9686 || orf19.4906 || || || Putative adhesin-like protein; positively regulated by Tbf1; Spider biofilm induced || 1 -0.67 -0.71 -0.74 -1.18 0.36 0.63 -0.68 -1.47 -0.94 -1.40 -1.16 -0.86 0.43 -0.51 -0.01 -0.42
9687 || orf19.7110 || || || Ortholog(s) have tRNA-specific adenosine-37 deaminase activity, role in tRNA modification and cytosol, nucleus localization || 1 -0.36 -0.39 -0.19 -0.13 0.05 0.09 -0.18 -0.62 -0.34 -0.46 -0.28 -0.39 0.03 -0.19 -0.19 -0.20
9688 || orf19.4287 || || || Putative oxidoreductase; Hap43-repressed gene; clade-associated gene expression || 1 -0.72 -0.73 -0.14 -0.52 -0.17 0.20 -0.66 -1.18 -0.26 -1.02 -1.24 0.08 -0.88 -0.73 -0.53 0.48
9689 || orf19.7629 || || || Ortholog(s) have Seh1-associated complex, cytosol, extrinsic to fungal-type vacuolar membrane, ribosome localization || 1 -0.46 -0.46 -0.20 -0.47 0.08 0.31 -0.51 -0.73 -0.10 -0.32 -0.82 -0.12 -0.63 0.07 0.05 -0.19
9690 || orf19.2495 || GSL1 || || Beta-1,3-glucan synthase subunit; 10 predicted transmembrane regions; caspofungin induced; repressed by yeast-to-hypha transition; young biofilm repressed, induced by biofilm drug exposure; Bcr1-repressed in RPMI a/a biofilms || 1 -0.90 -0.86 -0.17 -0.44 -0.15 0.20 -0.62 -0.85 -0.22 -0.60 -0.98 -0.36 -0.88 -0.03 -0.55 -0.09
9691 || orf19.2675 || || || Ortholog(s) have mRNA binding activity, role in spliceosomal complex assembly and U2 snRNP, U2-type prespliceosome localization || 1 -0.18 -0.50 -0.39 -0.12 0.19 0.48 -0.41 -0.61 -0.63 -0.31 -0.44 -0.25 -0.60 -0.27 -0.29 -0.25
9692 || orf19.3908 || MRV8 || || Protein of unknown function; Spider biofilm induced || 1 -1.40 -1.57 -1.44 0.08 0.56 1.05 -1.70 -2.03 -1.57 -0.53 -1.53 -0.25 -1.84 -1.64 -0.23 0.30
9693 || orf19.314 || || || Ortholog of S. cerevisiae : STB6, C. dubliniensis CD36 : Cd36_83110, C. parapsilosis CDC317 : CPAR2_103210, Candida tenuis NRRL Y-1498 : CANTEDRAFT_133418 and Debaryomyces hansenii CBS767 : DEHA2G08382g || 1 -0.42 -0.57 -0.16 -0.30 -0.31 -0.04 -0.88 -0.94 -0.07 -0.47 -0.78 -0.43 -0.88 -0.36 -0.71 0.18
9694 || orf19.280 || || || Ortholog of C. dubliniensis CD36 : Cd36_82875 and Candida albicans WO-1 : CAWG_02609 || 1 -0.72 -0.62 0.08 -0.16 -0.04 0.25 -1.33 -1.12 -0.65 -0.99 -0.98 -0.76 -0.91 -0.81 -0.82 -0.01
9695 || orf19.1409 || VAC7 || || Ortholog of S. cerevisiae Vac7; integral vacuolar membrane protein involved in vacuole inheritance and morphology; mutants are viable || 1 -0.47 -0.71 -0.51 -0.82 -0.09 -0.38 -0.94 -0.94 -0.77 -0.39 -0.80 -0.35 -0.70 -0.81 -0.03 -0.34
9696 || orf19.3328 || || || Putative transcription factor; S. cerevisiae ortholog Hot1 is required for the transient induction of glycerol biosynthetic genes GPD1 and GPP2 in response to high osmolarity; filament induced || 1 -0.61 -0.60 -0.35 -0.49 -0.39 -0.37 -0.97 -1.02 -1.01 -0.49 -0.77 -0.35 -0.18 -0.66 -0.01 -0.74
9697 || orf19.4575 || || || Ortholog(s) have mitochondrion localization || 1 -0.67 -0.75 -0.63 -0.35 -0.49 -0.07 -0.75 -0.94 -1.08 -0.86 -0.51 -0.23 -0.34 -0.60 -0.39 -0.49
9698 || orf19.151 || TPO5 || || Putative polyamine transporter; mutation confers hypersensitivity to toxic ergosterol analog; hyphal induced; macrophage induced || 1 -0.27 -0.67 0.07 -0.22 -0.13 0.08 -0.68 -0.82 -0.49 -0.29 -0.45 -0.49 -0.35 -0.31 -0.48 -0.32
9699 || orf19.7372 || MRR1 || || Putative Zn(II)2Cys6 transcription factor; regulator of MDR1 transcription; gain-of-function mutations cause upregulation of MDR1 (a plasma membrane multidrug efflux pump) and multidrug resistance; Hap43-induced || 1 -0.60 -0.87 0.08 -0.05 -0.13 0.06 -1.30 -1.28 -0.80 -0.15 -0.91 -0.43 -0.69 -0.55 -0.22 -0.67
9700 || orf19.1623 || CAP1 || || AP-1 bZIP transcription factor; apoptotic, oxidative stress response/resistance, multidrug resistance; nuclear in oxidative stress; complements S. cerevisiae yap1 mutant; oralpharyngeal candidasis-, human neutrophil, Spider biofilm induced || 1 -0.74 -0.80 -0.44 -0.53 0.06 0.50 -1.04 -1.33 -0.64 -0.86 -1.46 -0.83 -1.44 -0.85 -0.29 -0.67
9701 || CaalfMp02 || NAD6 || || Subunit 6 of NADH:ubiquinone oxidoreductase (NADH:ubiquinone dehydrogenase), a multisubunit enzyme complex (complex I) of the mitochondrial inner membrane that catalyzes the first step in mitochondrial respiration || 1 -0.67 -0.64 -0.62 -0.51 0.16 0.12 -1.21 -1.40 -1.05 -1.37 -0.90 -0.91 -1.12 -0.43 -0.46
9702 || orf19.6850 || || || Putative transcription factor with C3HC4 zinc finger DNA-binding motif; mutants are viable || 1 -0.82 -1.00 -1.29 -0.18 0.16 0.07 -1.41 -1.76 -1.01 -1.20 -1.25 -0.75 -1.04 -0.37 -0.67
9703 || orf19.2675 || || || Ortholog(s) have mRNA binding activity, role in spliceosomal complex assembly and U2 snRNP, U2-type prespliceosome localization || 1 -0.38 -0.57 -0.77 -0.41 -0.10 -0.05 -0.85 -0.82 -0.62 -0.34 -0.70 -0.62 -0.89 -0.49 -0.44 -0.58
9704 || orf19.3959 || SSD1 || || Protein with role in resistance to host antimicrobial peptides; virulence role in murine infection; functional homolog of S. cerevisiae Ssd1p, which suppresses various mutant phenotypes; constitutively expressed and not cell-cycle regulated || 1 -0.78 -0.85 -0.38 -0.16 -0.50 0.01 -0.93 -1.05 -0.67 -0.59 -0.71 -0.30 -0.74 -0.44 -0.40 -0.35
9705 || orf19.672 || || || Ortholog(s) have U5 snRNP localization || 1 -0.75 -0.84 -0.22 -0.28 -0.23 0.16 -0.91 -1.00 -0.55 -0.71 -0.51 -0.16 -0.79 -0.47 -0.56 -0.18
9706 || orf19.5710 || || || Nucleoporin component of central core of the nuclear pore complex; mRNA binds She3 || 1 -0.49 -0.56 -0.06 -0.12 -0.09 0.16 -0.65 -0.76 -0.41 -0.34 -0.40 0.07 -0.51 -0.18 -0.24 -0.10
9707 || orf19.7400 || ALS7 || || ALS family protein; hypermutable contingency gene; growth-regulated, downregulated in biofilm; two variable repeat regions; expression in S. cerevisiae does not confer adhesiveness; ALS family includes adhesins, cell-surface glycoproteins || 1 -1.19 -1.24 -0.18 -0.40 0.12 0.26 -1.37 -1.13 -0.63 -0.84 -0.87 -0.44 -1.02 -0.42 -0.63 -0.32
9708 || orf19.6926 || CSC25 || || Guanyl-nucleotide exchange factor; activator of Ras/adenylyl cyclase pathway; functional homolog of S. cerevisiae Cdc25p; commonly called Cdc25; transposon mutation affects filamentous growth || 1 -1.13 -1.20 -0.48 -0.99 0.11 0.37 -1.47 -1.45 -0.76 -0.90 -1.15 -0.15 -0.85 -0.25 -0.44 -0.38
9709 || orf19.7414 || ALS6 || || ALS family protein; expression in S. cerevisiae confers adhesion to gelatin; macrophage-induced gene; N-terminal adhesion domain; ALS family includes cell-surface glycoproteins, some with adhesin function || 1 -1.10 -0.99 -0.64 -0.93 -0.23 0.14 -1.55 -1.80 -0.86 -0.89 -0.88 -0.01 -0.80 -0.94 -0.53 -0.06
9710 || orf19.5736 || ALS5 || || ALS family adhesin; highly variable; expression in S. cerevisiae causes adhesion to human epithelium, endothelium or ECM, endothelial invasiveness by endocytosis and, at high abundance, ECM-induced aggregation; can form amyloid fibrils || 1 -0.88 -0.95 -0.49 -0.59 -0.08 0.27 -1.45 -1.90 -0.95 -0.67 -0.78 0.26 -1.27 -0.82 -0.29 0.10
9711 || orf19.6926 || CSC25 || || Guanyl-nucleotide exchange factor; activator of Ras/adenylyl cyclase pathway; functional homolog of S. cerevisiae Cdc25p; commonly called Cdc25; transposon mutation affects filamentous growth || 1 -1.06 -0.98 -0.14 -0.16 0.17 0.37 -1.04 -1.17 -0.67 -0.82 -0.91 0.08 -0.60 -0.68 -0.21 -0.16
9712 || orf19.432 || || || Predicted SCF ubiquitin ligase complex protein; Spider biofilm induced; rat catheter biofilm induced || 1 -0.49 -0.57 -0.16 -0.13 -0.12 0.34 -0.66 -0.71 -0.38 -0.55 -0.75 0.23 -0.51 -0.56 -0.20 -0.32
9713 || orf19.2296 || || || Predicted mucin-like protein; ketoconazole-induced; fluconazole-repressed; induced in cyr1 mutant; colony morphology-related gene regulation by Ssn6; flow model biofilm induced; Spider biofilm induced || 1 -1.02 -1.58 -0.54 -0.45 -2.32 -2.39 -1.41 -1.55 -1.10 0.16 -1.87 -1.85 -1.11
9714 || orf19.4531 || || || Putative PDR-subfamily ABC transporter; Spider biofilm induced || 1 -1.33 -1.20 -0.54 -0.35 -0.16 0.15 -1.60 -1.83 -0.90 -0.19 -1.08 0.28 -1.01 -0.75 0.45 -0.31
9715 || orf19.1409 || VAC7 || || Ortholog of S. cerevisiae Vac7; integral vacuolar membrane protein involved in vacuole inheritance and morphology; mutants are viable || 1 -0.53 -0.69 -0.22 -0.21 -0.23 -0.02 -0.96 -0.83 -0.43 -0.24 -0.69 0.20 -0.68 -0.43 -0.06 -0.15
9716 || orf19.432 || || || Predicted SCF ubiquitin ligase complex protein; Spider biofilm induced; rat catheter biofilm induced || 1 -1.21 -1.19 0.04 -0.51 -0.24 0.57 -1.53 -1.44 -0.39 -0.20 -1.12 0.34 -0.91 -0.89 -0.06 -0.26
9717 || orf19.1274 || || || Has domain(s) with predicted DNA binding, zinc ion binding activity, role in transcription, DNA-templated and nucleus localization || 1 -0.69 -0.53 -0.51 -0.25 -0.06 0.39 -0.70 -1.17 -0.33 -0.40 -0.79 0.20 -0.97 -0.92 -0.04 -0.26
9718 || orf19.1409 || VAC7 || || Ortholog of S. cerevisiae Vac7; integral vacuolar membrane protein involved in vacuole inheritance and morphology; mutants are viable || 1 -0.39 -0.30 -0.09 -0.16 0.08 0.06 -0.92 -0.80 -0.45 -0.18 -0.65 0.28 -0.39 -0.50 0.14 -0.34
9719 || orf19.2949 || IML1 || || Putative protein with a role in autophagy; rat catheter biofilm induced || 1 -0.26 -0.31 -0.48 -0.12 0.02 0.28 -0.86 -0.86 -0.75 -0.36 -0.52 -0.03 -0.31 -0.40 0.07 -0.57
9720 || orf19.5758 || SAL6 || || Putative protein phosphatase of the Type 1 family; serine/threonine-specific; similar to S. cerevisiae Ppq1; mutant has virulence defect; Spider biofilm induced || 1 -0.21 -0.36 -0.39 -0.32 -0.52 -0.09 -1.05 -1.20 -0.59 -0.17 -0.74 -0.13 -0.45 -0.47 0.17 -0.55
9721 || orf19.2340 || CDC48 || || Putative microsomal ATPase; plasma membrane-localized; regulated by Gcn2 and Gcn4; induced by amino acid starvation (3-AT); macrophage/pseudohyphal-repressed; protein levels decrease in stationary phase yeast; Spider biofilm repressed || 1 -0.50 -0.54 -0.29 -0.06 -0.43 -0.37 -0.69 -0.79 -0.68 -0.47 -0.59 -0.33 -0.69 -0.47 0.28 0.02
9722 || orf19.2340 || CDC48 || || Putative microsomal ATPase; plasma membrane-localized; regulated by Gcn2 and Gcn4; induced by amino acid starvation (3-AT); macrophage/pseudohyphal-repressed; protein levels decrease in stationary phase yeast; Spider biofilm repressed || 1 -0.44 -0.47 -0.24 -0.08 -0.34 -0.30 -0.69 -0.72 -0.64 -0.51 -0.50 -0.44 -0.80 -0.72 0.19 -0.20
9723 || orf19.4894 || || || Protein with similarity to S. cerevisiae Yer010cp, a protein of unknown function belonging to the prokaryotic RraA family; repressed by benomyl; Hap43-induced; Spider biofilm induced || 1 -1.04 -0.78 -0.63 -0.32 -0.72 0.18 -0.76 -0.80 -0.65 -0.77 -0.83 -0.74 -1.28 -0.53 -0.15 -0.87
9724 || orf19.3929 || || || Ortholog(s) have mitochondrion localization || 1 -0.59 -0.67 -0.35 -0.52 -0.12 -0.02 -0.59 -0.53 -0.29 -0.41 -0.58 -0.32 -1.07 -0.46 -0.29 -1.04
9725 || orf19.3139 || || || Putative NADP-dependent oxidoreductase; Hap43-repressed; induced by benomyl treatment; oxidative stress-induced via Cap1; rat catheter biofilm repressed || 1 -0.63 -1.09 -0.25 -0.37 -0.58 0.81 -1.02 -1.37 -0.83 -1.01 -0.71 -0.64 -2.21 -0.92 -0.60 -0.46
9726 || orf19.3139 || || || Putative NADP-dependent oxidoreductase; Hap43-repressed; induced by benomyl treatment; oxidative stress-induced via Cap1; rat catheter biofilm repressed || 1 -0.70 -0.59 0.01 -0.43 -0.37 1.15 -0.90 -1.21 -0.71 -1.02 -0.37 -0.37 -1.62 -0.66 -0.41 -0.09
9727 || orf19.2248 || ARE2 || || Acyl CoA:sterol acyltransferase; uses cholesterol and oleoyl-CoA substrates; protoberberine derivative drug inhibits enzyme activity; ketoconazole-induced; Hap43-repressed; flow model biofilm induced; Spider biofilm induced || 1 0.04 -0.02 -0.20 -0.31 0.41 1.09 -0.53 -0.92 -0.14 -1.20 -0.15 -0.10 -0.97 -0.60 -0.34 0.81
9728 || orf19.2173 || MAF1 || || Putative negative regulator of RNA polymerase III; decreased expression in hyphae vs yeast cells; caspofungin repressed; Spider biofilm repressed || 1 0.09 -0.09 0.20 -0.26 0.67 1.15 -0.98 -1.03 -0.70 -1.24 0.17 -0.39 -0.88 -0.59 -0.12 0.77
9729 || orf19.6225 || PCL7 || || Putative cyclin-like protein; possible Pho85 cyclin; hyphal repressed; induced by Mnl1 under weak acid stress || 1 0.20 -0.12 -0.10 -0.20 0.74 0.72 -0.64 -0.61 -0.26 -1.43 0.23 -0.04 -0.65 -0.34 -0.38 0.26
9730 || orf19.21 || || || Ortholog(s) have role in ethanol metabolic process and mitochondrial inner membrane localization || 1 -0.13 -0.14 -0.25 -0.77 0.73 1.11 -0.72 -0.76 -0.70 -1.53 0.43 -0.12 -0.57 -0.41 0.19 0.33
9731 || orf19.21 || || || Ortholog(s) have role in ethanol metabolic process and mitochondrial inner membrane localization || 1 -0.11 -0.08 -0.36 -0.62 0.71 1.29 -0.63 -0.95 -0.84 -1.52 0.34 -0.33 -0.66 -0.45 0.04 0.74
9732 || orf19.2173 || MAF1 || || Putative negative regulator of RNA polymerase III; decreased expression in hyphae vs yeast cells; caspofungin repressed; Spider biofilm repressed || 1 -0.18 -0.17 -0.80 -0.99 1.00 1.17 -1.31 -1.20 -1.30 -1.80 0.34 -0.24 -1.41 -0.94 0.17 0.88
9733 || orf19.2173 || MAF1 || || Putative negative regulator of RNA polymerase III; decreased expression in hyphae vs yeast cells; caspofungin repressed; Spider biofilm repressed || 1 -0.11 -0.14 -0.73 -1.02 0.99 1.17 -1.18 -1.24 -1.42 -2.04 0.36 -0.59 -1.35 -1.17 0.44 0.20
9734 || orf19.2173 || MAF1 || || Putative negative regulator of RNA polymerase III; decreased expression in hyphae vs yeast cells; caspofungin repressed; Spider biofilm repressed || 1 -0.12 -0.05 -0.18 -0.65 0.89 1.10 -1.34 -1.26 -1.19 -1.95 0.21 -0.93 -1.23 -1.51 0.19 0.24
9735 || orf19.1796 || || || Putative glyoxylate reductase; acts on glyoxylate and hydroxypyruvate substrates; Spider biofilm repressed || 1 -0.40 -0.42 -1.04 -0.95 0.82 0.87 -1.54 -1.02 -1.60 -1.45 0.12 -0.64 -1.26 -0.46 0.06 0.42
9736 || orf19.4657 || || || Ortholog(s) have phosphoprotein phosphatase activity, role in negative regulation of phospholipid biosynthetic process, nuclear envelope organization and Nem1-Spo7 phosphatase complex, integral to membrane, mitochondrion localization || 1 -0.26 -0.12 -0.29 -0.06 1.29 1.44 -0.92 -1.76 -1.60 -1.32 0.25 0.08 -0.96 -1.09 0.23 0.42
9737 || orf19.4657 || || || Ortholog(s) have phosphoprotein phosphatase activity, role in negative regulation of phospholipid biosynthetic process, nuclear envelope organization and Nem1-Spo7 phosphatase complex, integral to membrane, mitochondrion localization || 1 -0.12 -0.10 -0.28 0.14 1.41 1.32 -1.13 -1.58 -1.54 -1.22 0.54 0.32 -1.50 -0.67 0.29 0.26
9738 || orf19.7296 || || || Putative cation conductance protein; similar to stomatin mechanoreception protein; plasma-membrane localized; induced by Rgt1; rat catheter and Spider biofilm induced || 1 -0.15 -0.14 0.69 0.69 1.57 0.93 -1.29 -1.79 -0.50 -0.94 -0.69 0.44 -0.46 -0.96 0.44 -0.27
9739 || orf19.4132 || || || Protein of unknown function; UPF0057 protein family member; localizes to the plasma membrane; Spider biofilm induced || 1 0.14 -0.09 0.69 0.63 1.21 1.37 -1.64 -2.05 -1.45 -2.18 -0.65 -0.20 -0.46 -1.45 0.79 -0.72
9740 || orf19.1798 || TSC2 || || Putative GTPase-activating protein; similar to mammalian tuberin; involved in control of filamentous growth; mutants are viable || 1 -0.36 -0.04 -0.06 0.26 0.47 0.55 -0.36 -0.48 -0.51 -0.52 -0.61 0.18 -0.34 -0.65 0.23 -0.16
9741 || orf19.2898 || || || Ortholog(s) have borate efflux transmembrane transporter activity, role in borate transport, protein targeting to vacuole and fungal-type vacuole, plasma membrane localization || 1 0.04 0.09 0.24 0.49 0.27 0.73 -1.72 -2.28 -2.29 -1.55 -0.29 0.69 -2.33 -2.23 0.47 0.25
9742 || orf19.1979 || GIT3 || || Glycerophosphocholine permease; white cell specific transcript; fungal-specific; alkaline repressed; caspofungin, macrophage/pseudohyphal-repressed; flow model biofilm induced; Spider biofilm induced || 1 -0.29 -0.55 -0.52 -0.25 1.26 2.37 -3.83 -3.72 -4.71 -4.36 -0.04 0.34 -3.48 -5.02 0.83 -0.07
9743 || orf19.3682 || CWH8 || || Putative dolichyl pyrophosphate (Dol-P-P) phosphatase; ketoconazole-induced; expression is increased in a fluconazole-resistant isolate; clade-associated gene expression; Hap43p-induced gene || 1 -0.44 -0.53 -0.12 0.50 0.17 1.51 -0.89 -0.97 -1.29 -0.91 -0.42 0.31 -0.94 -0.95 0.41 0.08
9744 || orf19.313 || DAL4 || || Putative allantoin permease; fungal-specific (no human or murine homolog) || 1 -0.95 -0.80 -0.34 0.29 0.36 1.05 -1.35 -1.20 -0.99 -0.99 -0.88 0.63 -1.64 -1.35 0.02 0.82
9745 || orf19.313 || DAL4 || || Putative allantoin permease; fungal-specific (no human or murine homolog) || 1 -0.13 -0.94 -0.10 0.41 0.64 0.86 -1.57 -2.05 -0.66 -2.12 -0.97 0.24 -1.73 -2.15 -0.30 0.46
9746 || orf19.313 || DAL4 || || Putative allantoin permease; fungal-specific (no human or murine homolog) || 1 -0.71 -0.83 -0.09 0.55 0.85 1.41 -1.41 -2.13 -1.21 -2.09 -0.80 0.19 -1.95 -2.07 0.15 0.98
9747 || orf19.313 || DAL4 || || Putative allantoin permease; fungal-specific (no human or murine homolog) || 1 -0.43 -0.61 -0.05 0.43 0.07 1.41 -1.02 -1.32 -0.80 -1.29 -0.78 0.04 -1.37 -1.54 -0.31 0.13
9748 || orf19.360 || FUR4 || || Putative uracil permease || 1 -0.88 -1.10 -0.34 0.20 0.46 1.21 -1.00 -1.50 -1.59 -1.77 -0.60 0.47 -1.30 -1.78 -0.24 0.35
9749 || CaalfMp03 || NAD1 || || Subunit 6 of NADH:ubiquinone oxidoreductase (NADH:ubiquinone dehydrogenase), a multisubunit enzyme complex (complex I) of the mitochondrial inner membrane that catalyzes the first step in mitochondrial respiration || 1 -0.18 -0.31 0.21 0.77 0.49 1.16 -0.76 -1.04 -1.21 -1.41 -0.77 0.26 -0.99 -1.24 -0.19 0.24
9750 || orf19.1368 || || || Protein of unknown function; flow model biofilm induced; Spider biofilm induced || 1 -0.46 -0.43 0.41 0.22 0.32 1.23 -1.72 -2.24 -1.05 -2.32 -1.15 0.25 -1.05 -1.21 0.39 0.31
9751 || orf19.5102 || PLB5 || || Putative GPI-linked phospholipase B, fungal-specific (no mammalian homolog); null mutation eliminates cell-associated phospholipase A2 activity and attenuates virulence; fluconazole-repressed; flow model biofilm repressed || 1 -0.57 -0.64 -0.19 0.08 0.68 1.19 -1.08 -1.14 -1.06 -1.15 -0.20 0.15 -0.96 -1.07 0.69 0.37
9752 || orf19.3104 || YDC1 || || Alkaline dihydroceramidase; involved in sphingolipid metabolism; Mob2-dependent hyphal regulation; transcript is regulated by Nrg1 and Mig1; Hap43-repressed || 1 -0.90 -0.98 -0.06 -0.07 0.77 1.82 -1.42 -1.80 -1.59 -2.31 -0.29 0.33 -1.05 -1.98 0.99 -0.06
9753 || orf19.3104 || YDC1 || || Alkaline dihydroceramidase; involved in sphingolipid metabolism; Mob2-dependent hyphal regulation; transcript is regulated by Nrg1 and Mig1; Hap43-repressed || 1 -0.91 -0.98 0.04 -0.13 0.68 1.75 -1.63 -1.52 -1.72 -2.22 -0.48 0.06 -1.37 -1.85 0.57 -0.47
9754 || orf19.1183 || || || Ortholog(s) have fungal-type vacuole localization || 1 -0.69 -0.57 0.17 -0.14 0.65 1.41 -1.08 -1.13 -0.51 -1.32 -0.49 0.08 -0.66 -1.25 0.47 -0.52
9755 || orf19.1152 || || || Protein of unknown function; induced in core stress response; Gcn2 and Gcn4 regulated; flow model biofilm induced; Spider biofilm induced || 1 -0.95 -0.99 0.25 -0.36 0.27 1.40 -2.15 -2.25 -0.64 -2.12 -0.89 0.37 -1.66 -2.38 0.75 -0.41
9756 || orf19.6976 || || || Predicted MFS membrane transporter; member of the proton coupled folate transporter/heme carrier protein family; virulence-group-correlated expression; Spider biofilm induced || 1 -0.41 -0.55 -0.11 -0.14 0.54 1.20 -1.35 -1.65 -0.95 -0.87 -0.65 0.92 -1.05 -1.58 0.96 -0.37
9757 || orf19.1152 || || || Protein of unknown function; induced in core stress response; Gcn2 and Gcn4 regulated; flow model biofilm induced; Spider biofilm induced || 1 -0.06 -0.57 0.20 -0.31 0.72 1.76 -0.68 -1.22 -0.77 -1.94 -0.19 0.41 -0.85 -2.11 1.28 -0.36
9758 || orf19.1152 || || || Protein of unknown function; induced in core stress response; Gcn2 and Gcn4 regulated; flow model biofilm induced; Spider biofilm induced || 1 -0.30 -0.13 0.28 -0.28 0.94 1.49 -0.99 -1.40 -0.50 -1.97 -0.43 0.35 -0.34 -2.19 0.76 -0.38
9759 || orf19.1153 || GAD1 || || Putative glutamate decarboxylase; alkaline, macrophage-downregulated gene; amphotericin B induced; induced by Mnl1 under weak acid stress; stationary phase enriched protein; rat catheter biofilm repressed || 1 -0.81 -0.68 0.15 -0.39 1.24 2.15 -1.39 -1.99 -1.10 -2.86 0.11 0.41 0.11 -1.90 1.20 -0.20
9760 || orf19.1153 || GAD1 || || Putative glutamate decarboxylase; alkaline, macrophage-downregulated gene; amphotericin B induced; induced by Mnl1 under weak acid stress; stationary phase enriched protein; rat catheter biofilm repressed || 1 -0.21 -0.93 -0.06 -0.60 1.22 2.43 -1.27 -1.83 -1.30 -2.92 -0.01 0.51 0.02 -1.92 1.11 -0.14
9761 || orf19.2613 || ECM4 || || Cytoplasmic glutathione S-transferase; regulated by Nrg1, Tup1; induced in core stress response, in cyr1 or ras1 mutant (yeast or hyphal cells); Tn mutation affects filamentous growth; stationary phase enriched; Spider biofilm induced || 1 -0.42 -0.41 -0.14 -0.06 0.38 0.69 -0.49 -1.10 -0.46 -1.63 -0.29 -0.19 -0.63 -1.25 0.71 -0.56
9762 || orf19.2613 || ECM4 || || Cytoplasmic glutathione S-transferase; regulated by Nrg1, Tup1; induced in core stress response, in cyr1 or ras1 mutant (yeast or hyphal cells); Tn mutation affects filamentous growth; stationary phase enriched; Spider biofilm induced || 1 -0.66 -0.66 -0.42 -0.55 0.29 0.73 -0.41 -1.41 -0.46 -1.55 -0.22 -0.03 -0.99 -1.20 0.81 -0.41
9763 || orf19.246 || || || Predicted metalloendopeptidase; Spider biofilm induced || 1 -0.45 -1.18 0.08 -0.64 0.29 1.16 -1.00 -1.67 -1.07 -0.69 0.06 -0.28 -1.55 -1.43 0.28 -0.04
9764 || orf19.5395 || || || Ortholog(s) have role in early endosome to late endosome transport, regulation of protein complex assembly, vacuolar acidification and RAVE complex, extrinsic to membrane localization || 1 -0.21 -0.56 -0.12 -0.18 0.05 0.62 -0.90 -1.09 -0.18 -0.61 -0.18 0.32 -0.24 -0.50 0.18 0.39
9765 || orf19.3877 || || || Ortholog of C. dubliniensis CD36 : Cd36_73360 and Candida albicans WO-1 : CAWG_01936 || 1 -0.48 -0.48 -0.22 -0.30 0.37 0.62 -0.69 -0.51 -0.06 -0.77 -0.33 0.35 -0.33 -0.82 0.10 0.29
9766 || orf19.1307 || || || Predicted membrane protein; rat catheter biofilm induced || 1 -0.58 -0.59 -0.17 -0.22 -0.25 0.14 -0.61 -2.02 -0.92 -2.11 -0.95 0.38 -0.85 -1.71 0.04 0.74
9767 || orf19.1307 || || || Predicted membrane protein; rat catheter biofilm induced || 1 -0.00 -0.13 0.30 0.00 0.16 0.38 -0.51 -1.28 -0.24 -1.74 -0.47 0.52 -0.49 -1.70 0.17 0.95
9768 || orf19.7531 || || || Protein of unknown function; stationary phase enriched protein; induced upon yeast-hypha transition; benomyl or caspofungin induced; Hap43-repressed; Spider biofilm induced || 1 -0.15 -0.18 0.45 0.12 -0.38 0.79 -0.49 -1.43 -0.06 -1.35 -0.67 0.22 -0.86 -1.22 0.45 0.11
9769 || orf19.7531 || || || Protein of unknown function; stationary phase enriched protein; induced upon yeast-hypha transition; benomyl or caspofungin induced; Hap43-repressed; Spider biofilm induced || 1 -0.18 -0.25 0.48 0.21 -0.41 0.75 -0.33 -1.37 -0.15 -1.16 -0.55 -0.16 -0.63 -1.22 0.38 -0.06
9770 || orf19.286 || || || Has a predicted autophagy-related protein domain; transcription repressed by fluphenazine treatment || 1 -0.29 -0.74 -1.14 -0.50 0.18 0.82 -0.34 -0.90 -0.73 -0.72 -0.34 -0.67 -1.07 -0.74 0.06 -0.26
9771 || orf19.3908 || MRV8 || || Protein of unknown function; Spider biofilm induced || 1 -1.13 -0.91 -0.33 0.02 0.81 1.67 -1.38 -1.26 -0.68 -0.92 -1.08 -1.69 -1.64 -0.40 -0.04 0.57
9772 || orf19.847 || YIM1 || || Protein similar to protease of mitochondrial inner membrane; increased transcription is observed upon benomyl treatment; macrophage-downregulated gene || 1 -0.44 -0.47 -0.40 -0.35 0.56 0.89 -0.38 -0.70 -0.47 -0.87 -0.88 -0.83 -0.64 0.08 0.10 0.05
9773 || orf19.847 || YIM1 || || Protein similar to protease of mitochondrial inner membrane; increased transcription is observed upon benomyl treatment; macrophage-downregulated gene || 1 -0.43 -0.31 -0.32 -0.14 0.97 0.76 -0.23 -0.57 -0.58 -0.86 -0.69 -1.07 -0.84 -0.26 -0.07 -0.30
9774 || orf19.2723 || HIT1 || || Ortholog of S. cerevisiae Hit1; protein of unknown function required for high temperature growth; flow model biofilm induced; Spider biofilm induced || 1 -0.08 -0.14 -0.54 -1.14 0.79 1.57 -0.73 -1.36 -0.78 -0.20 -1.11 -1.70 -1.30 -1.11 -0.68 -0.60
9775 || orf19.2713 || || || Ortholog(s) have role in reciprocal meiotic recombination and nucleus localization || 1 -0.17 -0.28 -0.02 -0.67 0.66 1.06 -0.72 -1.05 -0.10 -0.51 -0.74 -1.22 -0.84 -0.44 -0.39 0.26
9776 || orf19.3879 || || || Predicted protein of unknown funtion; overlaps orf19.3879.1, which is a region annotated as blocked reading frame || 1 -1.20 -1.26 -1.21 -1.21 1.11 1.75 -1.26 -1.38 -0.40 -1.40 -0.79 -1.59 -0.99 -0.96 -0.59 -0.08
9777 || orf19.3879 || || || Predicted protein of unknown funtion; overlaps orf19.3879.1, which is a region annotated as blocked reading frame || 1 -0.87 -0.95 -1.12 -1.71 1.93 2.18 -1.02 -1.30 -0.24 -1.00 -1.46 -1.14 -0.69 -0.88 -0.68 0.07
9778 || orf19.7187 || MAM33 || || Putative mitochondrial acidic matrix protein; regulated by Ssn6p; protein present in exponential and stationary growth phase yeast cultures || 1 -0.55 -0.73 -0.35 -1.10 0.86 0.92 -0.60 -0.90 -0.34 -0.02 -1.38 -1.02 -1.32 -0.96 0.04 -1.09
9779 || orf19.7187 || MAM33 || || Putative mitochondrial acidic matrix protein; regulated by Ssn6p; protein present in exponential and stationary growth phase yeast cultures || 1 -0.69 -0.82 -0.62 -0.89 0.87 0.88 -1.05 -0.85 -0.24 -0.26 -1.75 -0.89 -1.25 -0.97 -0.32 -0.97
9780 || orf19.4997 || KIS2 || || Scaffold protein of Snf1p complex; similar to S. cerevisiae Gal83p and Sip2p; interacts with Snf4p; interaction with Snf1p complex is regulated by carbon source, decreased on ethanol; N-terminal myristoylation; Hog1p-downregulated || 1 -0.72 -0.79 -0.76 -1.06 0.40 0.09 -0.88 -0.89 -0.28 -0.26 -1.22 -0.21 -0.85 -0.76 -0.28 -0.54
9781 || orf19.3660 || || || Ortholog of C. dubliniensis CD36 : Cd36_60600, C. parapsilosis CDC317 : CPAR2_602890, Candida tenuis NRRL Y-1498 : CANTEDRAFT_135512 and Debaryomyces hansenii CBS767 : DEHA2F15312g || 1 -0.22 -0.34 0.05 -0.13 0.27 0.31 -0.13 -0.43 -0.34 -0.23 -0.09 -0.22 -0.14 -0.59 -0.08 -0.39
9782 || orf19.2624 || || || Protein of unknown function; downregulated by fluphenazine treatment or in an azole-resistant strain that overexpresses CDR1 and CDR2 || 1 -0.37 -0.55 -0.23 0.15 0.39 0.02 -1.06 -1.38 -1.14 -0.94 -0.01 -0.81 -0.23 -1.19 -0.25 -0.70
9783 || orf19.3682 || CWH8 || || Putative dolichyl pyrophosphate (Dol-P-P) phosphatase; ketoconazole-induced; expression is increased in a fluconazole-resistant isolate; clade-associated gene expression; Hap43p-induced gene || 1 0.01 -0.05 0.16 0.63 0.81 1.53 -0.95 -0.70 -0.99 -0.64 -0.10 0.08 -0.75 -1.47 0.48 -0.78
9784 || orf19.6976 || || || Predicted MFS membrane transporter; member of the proton coupled folate transporter/heme carrier protein family; virulence-group-correlated expression; Spider biofilm induced || 1 -0.14 -0.51 0.32 0.33 0.72 1.33 -1.86 -1.59 -1.00 -0.30 -0.33 0.66 -1.40 -2.14 1.06 -1.04
9785 || orf19.3708 || SAP2 || || Major secreted aspartyl proteinase; utilization of protein as nitrogen source; role in virulence complicated by URA3 effects; immunoprotective; regulated by growth, albumin, drugs, white cell-type; flow model biofilm induced || 1 -0.21 0.19 0.70 -0.16 0.09 1.40 -1.50 -1.02 -0.08 -0.75 -0.97 1.14 -0.83 -1.20 1.03 -0.60
9786 || orf19.1409 || VAC7 || || Ortholog of S. cerevisiae Vac7; integral vacuolar membrane protein involved in vacuole inheritance and morphology; mutants are viable || 1 -0.41 -0.34 0.09 0.05 0.10 0.34 -0.76 -0.62 -0.13 -0.15 -0.53 0.41 -0.11 -0.66 0.18 -0.07
9787 || orf19.2949 || IML1 || || Putative protein with a role in autophagy; rat catheter biofilm induced || 1 -0.27 -0.19 -0.20 0.01 0.41 0.64 -0.77 -0.64 -0.08 -0.10 -0.28 0.41 -0.21 -0.18 0.67 -0.16
9788 || orf19.6308 || || || Ortholog of Candida albicans WO-1 : CAWG_01818 || 1 -0.14 -0.29 -0.29 -0.00 0.46 0.20 -0.85 -0.69 -0.47 -0.35 -0.44 0.21 -0.85 -0.22 0.55 -0.13
9789 || orf19.1409 || VAC7 || || Ortholog of S. cerevisiae Vac7; integral vacuolar membrane protein involved in vacuole inheritance and morphology; mutants are viable || 1 0.24 -0.05 0.07 0.03 0.40 0.16 -0.66 -0.47 -0.27 -0.22 -0.42 0.17 -0.26 -0.29 0.44 -0.03
9790 || orf19.3176 || RIM21 || || Plasma membrane pH-sensor involved in the Rim101 pH response pathway; required for processing and activation of Rim101 and for alkaline pH-induced hyphal growth; Spider biofilm induced || 1 0.08 0.03 0.31 -0.14 0.34 0.42 -0.74 -0.72 -0.05 -0.30 -0.45 -0.33 -0.21 -0.24 0.10 -0.09
9791 || orf19.7159 || || || Putative protein of unknown function; Hap43p-repressed gene; ortholog of S. cerevisiae YMR185W || 1 0.05 0.17 0.35 -0.24 0.92 1.37 -0.61 -0.74 0.06 0.17 -0.31 0.20 -0.59 -0.93 0.32 0.08
9792 || orf19.1589 || || || Putative transcription factor component of the core factor (CF) rDNA transcription factor complex; Spider biofilm induced || 1 0.62 0.20 -0.12 -0.03 1.38 1.74 -0.45 -0.60 -0.25 0.09 -0.67 -0.42 -0.52 -0.85 0.11 -0.26
9793 || orf19.1771 || CWC22 || || Predicted spliceosome-associated protein; role in pre-mRNA splicing; Spider biofilm induced || 1 0.57 0.34 0.24 0.17 1.11 1.25 -0.05 -0.69 0.10 0.20 -0.74 -0.48 0.09 -1.27 0.65 -1.43
9794 || orf19.7106 || VPS70 || || Ortholog(s) have role in protein targeting to vacuole and endoplasmic reticulum localization || 1 0.03 0.10 0.35 0.23 0.46 0.72 -0.25 -0.32 -0.12 -0.22 -0.38 -0.03 -0.11 -0.43 0.75 -0.40
9795 || orf19.6688 || || || Protein of unknown function; expression decreases by benomyl treatment or in an azole-resistant strain overexpressing MDR1; Spider biofilm induced || 1 -0.46 -0.23 0.57 0.26 1.88 2.93 -1.03 -2.06 -0.52 -0.39 -1.92 -1.34 -0.47 -2.05 2.85 -1.97
9796 || orf19.1287 || || || Protein of unknown function; flow model biofilm induced; Spider biofilm induced || 1 0.09 0.14 0.11 -0.66 2.34 2.36 -0.62 -1.68 -0.98 -1.57 -2.07 -0.09 0.22 -2.19 0.96 -2.83
9797 || orf19.1287 || || || Protein of unknown function; flow model biofilm induced; Spider biofilm induced || 1 0.03 -0.27 -0.28 -1.11 2.47 2.68 -0.85 -2.29 -1.16 -1.69 -2.82 -0.05 -0.04 -2.51 1.03 -2.45
9798 || orf19.6350 || || || Ortholog of C. dubliniensis CD36 : Cd36_11890 and Candida albicans WO-1 : CAWG_00170 || 1 -0.31 -0.22 0.62 -0.04 1.00 2.87 -0.90 -1.11 -0.86 -1.06 -1.09 -0.57 -0.56 -2.22 -0.02 -0.82
9799 || orf19.6760 || MDS3 || || TOR signaling pathway component; required for growth and hyphal formation at alkaline pH, for full virulence in a mouse model of systemic infection and for SD and Spider medium biofilm formation; role in chlamydospore formation || 1 -0.28 -0.36 0.44 -0.10 0.80 0.86 -0.32 -0.57 -0.11 -0.34 -0.19 -0.33 -0.03 -0.62 0.35 -0.53
9800 || orf19.7283 || || || Protein of unknown function; rat catheter and Spider biofilm induced || 1 -0.25 0.00 0.77 -0.37 2.50 2.48 -0.45 -0.56 0.18 -1.27 -1.54 -1.23 -0.50 -1.48 0.38 -1.03
9801 || orf19.6706 || GYP7 || || Protein similar to S. cerevisiae Gyp7p (GTPase-activating protein for Ypt1p); caspofungin-induced || 1 -0.06 0.03 0.38 0.09 0.68 0.79 -0.52 -0.45 0.11 -0.38 -0.47 0.02 -0.74 0.38 0.37 0.03
9802 || orf19.1623 || CAP1 || || AP-1 bZIP transcription factor; apoptotic, oxidative stress response/resistance, multidrug resistance; nuclear in oxidative stress; complements S. cerevisiae yap1 mutant; oralpharyngeal candidasis-, human neutrophil, Spider biofilm induced || 1 0.01 -0.16 0.37 0.37 0.70 1.27 -0.48 -0.50 0.23 -0.28 -0.62 -0.03 -0.74 -0.02 0.32 -0.47
9803 || orf19.5536 || || || Has domain(s) with predicted carbon-nitrogen ligase activity, with glutamine as amido-N-donor, hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides activity || 1 -0.16 0.18 0.49 0.60 0.64 0.89 -0.56 -0.85 -0.09 -0.47 -1.01 -0.24 -0.05 -0.09 0.27 0.14
9804 || orf19.428 || || || Putative serine/threonine kinase; induced during planktonic growth; rat catheter biofilm repressed || 1 -0.25 -0.16 0.72 0.70 0.96 1.61 -0.22 -1.05 -0.34 -0.98 -0.72 -0.39 -0.17 -0.33 0.38 0.19
9805 || orf19.3589 || SPO11 || || DNA endonuclease; required for genetic recombination between homologous chromosomes during the parasexual cycle; produced in mitotically dividing cells; similar to S. cerevisiae Spo11 which functions in recombination during meiosis || 1 -0.36 -0.09 0.57 0.43 0.64 1.65 -0.67 -0.90 -0.17 -0.90 -0.47 -0.29 -0.18 0.19 0.06 -0.12
9806 || orf19.6722 || || || Protein similar to S. cerevisiae Rad4p; down-regulation associated with azole resistance || 1 -0.37 -0.29 0.11 0.23 0.94 1.53 -0.66 -0.75 -0.46 -0.01 -0.52 0.13 -0.60 -0.25 0.32 -0.08
9807 || orf19.5956 || PIN3 || || Putative SH3-domain-containing protein; predicted role in actin cytoskeleton organization; Spider biofilm repressed || 1 -0.25 -0.24 0.36 0.62 0.65 0.82 -1.01 -1.17 -0.38 -0.72 -0.80 -0.04 -0.56 0.01 0.97 -0.44
9808 || orf19.5763 || || || Has domain(s) with predicted oxidoreductase activity and role in metabolic process || 1 0.17 0.54 0.93 0.63 1.11 1.61 -0.93 -0.97 -0.50 -0.68 -0.96 -1.18 -1.24 -0.24 1.10 -0.28
9809 || orf19.5960 || NCE102 || || Non classical protein export protein; localized to plasma membrane; Hap43-induced gene; flow model biofilm induced; Spider biofilm induced || 1 0.07 -0.06 0.86 0.24 -1.27 -1.24 -0.68 -0.83 -0.77 -0.08 -0.60 -1.00 0.96 -0.36
9810 || orf19.3150 || GRE2 || || Putative reductase; Nrg1 and Tup1-regulated; benomyl- and hyphal-induced; macrophage/pseudohyphal-repressed; repressed by low iron; possibly involved in osmotic stress response; stationary phase enriched protein; Spider biofilm induced || 1 -0.09 -0.10 0.84 0.88 0.77 1.75 -0.72 -1.10 -0.56 -0.70 -0.70 -0.08 -0.73 -0.94 1.21 0.04
9811 || orf19.673 || || || Has domain(s) with predicted FMN binding, oxidoreductase activity and role in oxidation-reduction process || 1 -0.13 -0.33 0.71 0.68 0.69 1.75 -0.74 -0.99 -0.34 -0.95 -1.01 -0.04 -0.55 -0.44 0.73 0.04
9812 || orf19.3542 || LEM3 || || Putative membrane protein; mutation increases resistance to miltefosine; early-stage flow model biofilm induced || 1 -0.00 -0.03 0.26 0.28 0.43 0.61 -0.40 -0.44 -0.25 -0.28 -0.47 -0.15 -0.24 -0.10 0.44 0.01
9813 || orf19.3679 || || || Putative protein of unknown function; stationary phase enriched protein || 1 -0.26 -0.51 0.23 0.58 1.47 1.79 -1.33 -1.05 -0.63 -0.52 -0.60 -0.61 -1.55 -0.85 0.86 -0.62
9814 || orf19.3679 || || || Putative protein of unknown function; stationary phase enriched protein || 1 -0.21 -0.41 0.28 0.27 1.16 1.75 -0.64 -0.59 -0.45 -0.51 -0.55 -0.50 -1.12 -0.78 0.81 -0.28
9815 || orf19.1069 || RPN4 || || C2H2 transcription factor; putative regulator of proteasome genes; DNA recognition sequence (GAAGGCAAAA) enriched in regions upstream of proteasome genes; induced in core stress response; Hap43-induced; Spider biofilm induced || 1 0.04 0.07 0.53 0.18 1.45 1.82 -0.96 -1.09 -0.50 -0.86 -0.75 -0.84 -0.87 -0.95 1.08 -0.33
9816 || orf19.673 || || || Has domain(s) with predicted FMN binding, oxidoreductase activity and role in oxidation-reduction process || 1 -0.44 -0.25 0.14 0.04 1.23 2.04 -1.17 -0.41 -1.17 -0.85 -0.99 -0.30 -0.42 -1.19 1.05 -0.30
9817 || orf19.3021 || || || Putative protein of unknown function; Hap43-repressed gene; Spider biofilm induced || 1 -0.13 -0.25 0.02 0.15 0.88 1.73 -0.94 -1.05 -0.55 -0.65 -1.25 -0.41 -1.24 -0.02 0.76 0.38
9818 || orf19.2690 || || || Putative mitochondrial GTPase; required for mitochondrial morphology and genome maintenance; Spider biofilm induced || 1 0.12 0.12 0.37 0.22 0.64 0.92 -0.43 -0.66 -0.28 -0.28 -0.75 0.04 -0.61 -0.14 0.58 0.35
9819 || orf19.2703 || || || Specificity factor required for ubiquitination and sorting of specific cargo proteins at the multivesicular body; ortholog of S. cerevisiae Ear1; transcript regulated by iron; Ssr1-represssed; Spider biofilm induced || 1 0.08 0.12 0.47 -0.18 0.94 0.80 -0.41 -0.73 -0.39 -0.36 -0.35 -0.13 -0.41 -0.00 0.44 0.19
9820 || orf19.3542 || LEM3 || || Putative membrane protein; mutation increases resistance to miltefosine; early-stage flow model biofilm induced || 1 0.10 0.07 0.23 0.03 0.61 0.73 -0.40 -0.42 -0.25 -0.23 -0.31 -0.03 -0.19 -0.03 0.57 0.24
9821 || orf19.3021 || || || Putative protein of unknown function; Hap43-repressed gene; Spider biofilm induced || 1 -0.05 0.08 0.01 -0.31 1.66 1.78 -0.61 -1.03 -0.47 -1.06 -1.09 -0.53 -0.56 -0.14 1.03 0.40
9822 || orf19.2703 || || || Specificity factor required for ubiquitination and sorting of specific cargo proteins at the multivesicular body; ortholog of S. cerevisiae Ear1; transcript regulated by iron; Ssr1-represssed; Spider biofilm induced || 1 0.17 0.01 -0.07 -0.22 0.79 0.84 -0.23 -0.64 -0.41 -0.31 -0.34 -0.31 -0.41 -0.20 0.58 0.09
9823 || orf19.48 || RPM2 || || Mitochondrial RNase P subunit; roles in nuclear transcription, cytoplasmic and mitochondrial RNA processing, mitochondrial translation; virulence-group-correlated expression; likely essential (UAU1 method); rat catheter biofilm induced || 1 -0.22 -0.15 0.01 0.03 1.12 1.18 -0.60 -0.84 -0.39 -0.70 -0.79 0.11 -0.35 -0.48 0.98 0.11
9824 || orf19.48 || RPM2 || || Mitochondrial RNase P subunit; roles in nuclear transcription, cytoplasmic and mitochondrial RNA processing, mitochondrial translation; virulence-group-correlated expression; likely essential (UAU1 method); rat catheter biofilm induced || 1 -0.14 -0.16 -0.15 -0.16 0.46 0.50 -0.33 -0.61 -0.15 -0.45 -0.68 -0.28 -0.13 -0.12 0.76 -0.09
9825 || orf19.896 || CHK1 || || Histidine kinase; 2-component signaling, cell wall synthesis; hyphal growth defect; avirulent in mouse, not rat vaginal infection; phagocytosis rate increased; Spider biofilm induced; required for RPMI biofilm; Bcr1-induced in a/a biofilm || 1 0.09 0.03 -0.02 0.12 0.80 1.33 -1.08 -1.55 -0.88 -0.75 -1.10 -0.73 -0.25 0.10 0.92 -0.25
9826 || orf19.3586 || || || Ortholog(s) have role in fungal-type cell wall organization, vesicle-mediated transport and integral to endoplasmic reticulum membrane localization || 1 -0.30 -0.25 -0.04 -0.11 0.87 1.11 -0.81 -1.07 -0.67 -0.63 -0.74 -0.45 -0.23 0.15 1.26 0.14
9827 || orf19.3586 || || || Ortholog(s) have role in fungal-type cell wall organization, vesicle-mediated transport and integral to endoplasmic reticulum membrane localization || 1 -0.05 -0.25 -0.21 0.04 0.83 0.88 -0.94 -0.94 -0.60 -0.39 -0.70 -0.48 -0.12 0.19 1.23 0.08
9828 || orf19.896 || CHK1 || || Histidine kinase; 2-component signaling, cell wall synthesis; hyphal growth defect; avirulent in mouse, not rat vaginal infection; phagocytosis rate increased; Spider biofilm induced; required for RPMI biofilm; Bcr1-induced in a/a biofilm || 1 0.18 0.16 -0.25 -0.10 0.89 1.27 -0.53 -0.80 -0.67 -0.21 -0.85 -0.50 -0.17 0.42 1.04 -0.11
9829 || orf19.86 || || || Putative glutathione peroxidase; induced by peroxide, exposure to neutrophils and macrophage blood fractions; repressed during infection of macrophages; Spider biofilm induced; flow model biofilm repressed || 1 0.52 0.56 0.19 -0.42 0.72 1.01 -0.51 -0.67 -0.22 -0.65 -1.09 -0.69 -0.81 -0.41 0.68 -0.48
9830 || orf19.7619 || || || Protein with a mitochondrial distribution and morphology domain; possibly an essential gene, disruptants not obtained by UAU1 method; rat catheter and Spider biofilm induced || 1 -0.11 -0.19 -0.03 -0.26 0.78 0.86 -0.40 -0.72 -0.26 -0.31 -0.87 -0.41 -0.19 0.16 0.56 -0.57
9831 || orf19.7619 || || || Protein with a mitochondrial distribution and morphology domain; possibly an essential gene, disruptants not obtained by UAU1 method; rat catheter and Spider biofilm induced || 1 -0.12 -0.20 0.03 -0.10 0.53 0.84 -0.74 -0.97 -0.20 -0.03 -1.10 -0.34 -0.25 0.12 0.30 -0.73
9832 || orf19.6416 || || || Protein involved in N-glycosylation; Spider biofilm induced; rat catheter biofilm repressed || 1 -0.31 -0.56 0.30 0.12 0.14 0.44 -0.44 -0.90 -0.21 -0.40 -1.34 -0.19 -0.05 -0.01 0.48 -0.71
9833 || orf19.215 || || || Component of a complex containing the Tor2p kinase; possible a role in regulation of cell growth; Spider biofilm induced || 1 -0.18 -0.07 0.11 0.35 0.21 0.46 -0.12 -1.38 -1.42 -1.12 -0.85 -0.39 -0.31 -0.50 0.62 -0.55
9834 || orf19.4953 || || || Putative ATPase; predicted role in ER-associated protein catabolism; induced during chlamydospore formation in both C. albicans and C. dubliniensis; rat catheter biofilm repressed || 1 0.22 0.23 -0.22 -0.46 0.68 0.87 -0.87 -1.04 -0.99 -1.60 -0.54 -0.40 -0.87 -0.52 0.77 -0.35
9835 || orf19.2440 || || || S. cerevisiae ortholog Rtt101 is a cullin subunit of E3 ubiquitin ligase complex with a role in anaphase progression; induced by alpha pheromone in SpiderM medium || 1 0.17 0.21 -0.24 -0.42 0.28 0.13 -0.27 -0.60 -0.56 -0.53 -0.45 -0.34 -0.29 -0.22 0.15 -0.20
9836 || orf19.4941 || TYE7 || || bHLH transcription factor; control of glycolysis; required for biofilm formation; hyphally regulated by Cph1, Cyr1; flucytosine, Hog1 induced; amphotericin B, caspofungin repressed; induced in flow model biofilm and planktonic cultures || 1 0.31 0.33 -0.18 -1.08 0.79 1.20 -1.24 -1.64 -1.99 -1.04 -1.13 -0.94 -0.86 -0.19 0.09 -0.77
9837 || orf19.4941 || TYE7 || || bHLH transcription factor; control of glycolysis; required for biofilm formation; hyphally regulated by Cph1, Cyr1; flucytosine, Hog1 induced; amphotericin B, caspofungin repressed; induced in flow model biofilm and planktonic cultures || 1 0.55 0.57 0.09 -0.82 1.10 1.51 -0.87 -1.31 -1.80 -0.81 -0.80 -0.94 -0.47 -0.01 0.44 -0.55
9838 || orf19.4941 || TYE7 || || bHLH transcription factor; control of glycolysis; required for biofilm formation; hyphally regulated by Cph1, Cyr1; flucytosine, Hog1 induced; amphotericin B, caspofungin repressed; induced in flow model biofilm and planktonic cultures || 1 0.40 0.53 0.13 -0.67 0.92 -1.16 -1.54 -1.75 -0.65 -0.76 -0.35 -0.84 0.53 0.40 -0.35
9839 || orf19.7400 || ALS7 || || ALS family protein; hypermutable contingency gene; growth-regulated, downregulated in biofilm; two variable repeat regions; expression in S. cerevisiae does not confer adhesiveness; ALS family includes adhesins, cell-surface glycoproteins || 1 -0.33 -0.42 0.10 0.06 0.36 0.15 -0.38 -0.19 -0.30 -0.55 -0.57 -0.05 -0.27 -0.79 -0.01 -0.06
9840 || orf19.1990 || SNX4 || || Putative sorting nexin; induced during the mating process || 1 -0.06 -0.18 0.06 -0.75 0.47 -0.12 -0.72 -0.94 -0.61 -0.81 -1.00 -0.33 -0.30 -0.46 -0.55 0.16
9841 || orf19.5815 || SCT2 || || Putative glycerol-3-phosphate acyltransferase; fungal-specific (no human or murine homolog) || 1 0.04 -0.16 -0.36 -0.19 0.19 0.17 -0.44 -0.52 -0.04 -0.43 -0.47 -0.02 -0.31 -0.12 -0.13 0.25
9842 || orf19.5163 || SFI1 || || Putative centrin-binding protein; predicted role in spindle pole body duplication; induced by alpha pheromone in SpiderM medium; essential for growth || 1 -0.13 -0.16 -0.06 -0.29 0.63 0.29 -0.34 -0.37 -0.40 -0.33 -0.29 -0.03 -0.47 -0.23 0.13 0.07
9843 || orf19.2079 || PHHB || || Putative 4a-hydroxytetrahydrobiopterin dehydratase; transposon mutation affects filamentous growth; flow model biofilm induced; Spider biofilm induced || 1 -0.93 -0.79 -0.53 -0.35 2.11 0.96 -0.39 -1.07 -0.42 -0.80 -1.12 -0.31 -1.25 -0.68 0.49 -0.19
9844 || orf19.2079 || PHHB || || Putative 4a-hydroxytetrahydrobiopterin dehydratase; transposon mutation affects filamentous growth; flow model biofilm induced; Spider biofilm induced || 1 -0.14 -0.18 -0.26 0.04 2.05 0.64 0.08 -0.66 -0.26 -0.59 -0.75 -0.67 -0.56 -0.74 0.47 -0.38
9845 || orf19.5429 || || || Ortholog(s) have DNA replication origin binding, ubiquitin-protein ligase activity || 1 0.01 -0.41 0.14 0.04 0.25 0.23 -0.11 -0.14 -0.00 -0.26 -0.28 -0.07 -0.15 -0.17 0.21 -0.07
9846 || orf19.4691 || MRV1 || || Ortholog of Candida albicans WO-1 : CAWG_03682 || 1 -0.80 -1.13 0.65 -0.00 0.91 0.98 -0.59 -0.73 0.03 -0.65 -0.59 -0.14 -0.67 -0.08 0.22 -0.59
9847 || orf19.5446 || || || Putative protein of unknown function; transcript is upregulated in clinical isolates from HIV+ patients with oral candidiasis; regulated by Ssn6 || 1 -0.37 -0.88 -0.09 0.65 0.24 1.24 -1.42 -1.39 0.15 -0.61 -0.65 -0.26 -0.87 0.02 -0.78 -0.25
9848 || orf19.6508 || || || Ortholog(s) have protein transporter activity, role in Golgi to plasma membrane transport, intracellular protein transport and vesicle coat localization || 1 -0.58 -0.90 0.18 -0.13 0.20 0.26 -0.61 -0.38 -0.13 0.02 -0.39 0.16 -0.44 0.40 -0.12 0.33
9849 || orf19.589 || VPS21 || || Late endosomal Rab small monomeric GTPase involved in transport of endocytosed proteins to the vacuole; involved in filamentous growth and virulence; Spider biofilm induced || 1 -0.43 -0.54 -0.07 0.15 -0.01 0.23 -0.27 -0.44 0.03 -0.29 -0.25 0.05 -0.13 0.15 0.12 0.14
9850 || orf19.6121 || MNL1 || || Transcription factor; induces transcripts of stress response genes via SLE (STRE-like) elements; required for adaptation to weak acid stress; activates a subset of the genes that are repressed by Nrg1 || 1 -0.46 -0.20 -0.01 -0.09 0.28 0.77 -0.70 -0.72 -0.02 -0.41 -0.44 0.18 -0.01 0.23 0.18 0.15
9851 || orf19.7257 || MLH3 || || Ortholog(s) have role in meiotic mismatch repair, reciprocal meiotic recombination and MutLbeta complex localization || 1 -0.70 -0.41 0.03 -0.17 0.36 0.87 -0.75 -0.58 0.07 -0.34 -0.33 0.35 -0.44 0.02 0.40 0.35
9852 || orf19.7403 || || || Ortholog of S. cerevisiae : YML020W, C. glabrata CBS138 : CAGL0J10538g, C. dubliniensis CD36 : Cd36_86190, C. parapsilosis CDC317 : CPAR2_404740 and Candida tenuis NRRL Y-1498 : CANTEDRAFT_107670 || 1 -0.13 -0.24 0.04 -0.12 0.44 0.49 -0.40 -0.37 -0.15 -0.12 -0.30 0.44 -0.60 0.19 -0.00 0.48
9853 || orf19.6243 || VPS34 || || Autophosphorylated class III phosphatidylinositol 3-kinase; required for normal vesicle transport, hyphal growth, fibroblast adherence, virulence in mouse systemic infection; growth-regulated; caspofungin and hydrogen peroxide sensitivity || 1 -0.51 -0.64 0.23 -0.25 0.25 0.36 -0.86 -0.81 -0.18 -0.36 -0.64 0.29 -0.76 -0.21 -0.19 0.83
9854 || orf19.6800 || POS5 || || Protein similar to S. cerevisiae Pos5p, a mitochondrial NADH kinase involved in the oxidative stress response; planktonic growth-induced gene; likely to be essential for growth, based on an insertional mutagenesis strategy || 1 0.03 -0.06 0.13 -0.30 0.22 0.46 -0.66 -0.62 -0.14 -0.60 -0.44 0.08 -0.50 -0.13 -0.10 0.59
9855 || orf19.7058 || || || Ortholog(s) have role in cellular response to cadmium ion, detoxification of cadmium ion and cytoplasm, nucleus localization || 1 0.08 -0.13 0.22 -0.24 0.16 0.51 -0.55 -0.51 -0.07 -0.48 -0.50 0.49 -0.57 -0.27 -0.29 0.33
9856 || orf19.814 || SSY1 || || Amino acid sensor; required for wild-type hyphal growth on solid serum or Lees media, not under all conditions; 12 predicted membrane spanning regions; Hap43-repressed; Spider biofilm induced || 1 -0.37 -0.57 0.08 0.09 0.34 0.64 -0.70 -0.98 -0.54 -0.94 -1.09 0.12 -0.86 0.15 -0.07 0.23
9857 || orf19.7400 || ALS7 || || ALS family protein; hypermutable contingency gene; growth-regulated, downregulated in biofilm; two variable repeat regions; expression in S. cerevisiae does not confer adhesiveness; ALS family includes adhesins, cell-surface glycoproteins || 1 -0.40 -0.48 0.40 0.33 0.36 0.81 -0.34 -0.60 -0.22 -0.68 -0.61 0.18 -0.51 0.01 0.02 0.18
9858 || orf19.6470 || AHP2 || || Putative thiol-specific peroxiredoxin; macrophage-downregulated gene || 1 -0.15 -0.17 0.21 -0.15 0.26 0.88 -0.30 -0.33 -0.07 -0.40 -0.06 0.34 -0.52 -0.23 -0.03 0.10
9859 || orf19.2394 || || || Ortholog(s) have cytoplasm, nucleus localization || 1 -0.38 -0.52 0.38 0.11 0.05 0.78 -0.56 -0.32 -0.43 -0.20 -0.16 0.13 -0.37 -0.25 0.13 0.25
9860 || orf19.6679 || || || Ortholog(s) have cytosol, nucleus localization || 1 -0.47 -0.49 -0.06 0.03 -0.14 0.63 -0.60 -0.31 -0.00 0.01 -0.58 0.36 -0.75 -0.40 0.06 0.07
9861 || orf19.5776 || TOM1 || || Putative E3 ubiquitin ligase; transcript regulated by Nrg1 and Mig1 || 1 -0.38 -0.53 0.08 0.07 0.02 0.21 -0.49 -0.22 0.08 -0.34 -0.16 0.15 -0.62 -0.21 0.28 0.22
9862 || orf19.4744 || || || Putative phosphatidylinositol 3-phosphate (PI3P) phosphatase; repressed by alpha pheromone in SpiderM medium || 1 -0.43 -0.34 0.23 0.01 -0.15 0.11 -0.54 -0.30 0.11 -0.10 -0.43 0.30 -0.81 0.02 0.09 0.55
9863 || orf19.1717 || || || Ortholog of C. dubliniensis CD36 : Cd36_81270, C. parapsilosis CDC317 : CPAR2_502880, Candida tenuis NRRL Y-1498 : CANTEDRAFT_101483 and Debaryomyces hansenii CBS767 : DEHA2A11990g || 1 -0.11 -0.39 0.12 -0.46 -0.23 0.51 -0.87 -0.60 -0.44 0.17 -0.62 0.36 -0.70 0.11 -0.22 0.50
9864 || orf19.4744 || || || Putative phosphatidylinositol 3-phosphate (PI3P) phosphatase; repressed by alpha pheromone in SpiderM medium || 1 -0.47 -0.27 -0.00 -0.19 -0.05 0.01 -0.51 -0.74 -0.04 -0.13 -0.23 0.51 -0.36 0.12 -0.07 0.15
9865 || orf19.3815 || || || Has domain(s) with predicted ubiquitin thiolesterase activity and role in ubiquitin-dependent protein catabolic process || 1 -0.37 -0.32 0.12 -0.18 0.24 0.20 -0.15 -0.66 -0.14 -0.39 -0.25 0.32 -0.28 0.51 -0.24 0.09
9866 || orf19.4372 || || || Predicted transmembrane transporter; rat catheter and Spider biofilm induced || 1 -0.47 -0.56 0.01 -0.14 0.44 0.09 -0.40 -0.73 0.14 -1.06 -0.36 -0.41 -0.79 0.26 -0.25 0.68
9867 || orf19.4742 || || || Putative SH3-domain-containing protein || 1 -0.46 -0.42 0.17 -0.36 0.62 0.87 -0.66 -0.57 0.25 -0.89 -0.28 -0.21 -0.08 -0.05 -0.32 0.78
9868 || orf19.5159 || DUG3 || || Putative glutamine amidotransferase (GATase II); role in glutathione catabolism; || 1 -0.36 -0.24 0.33 -0.30 0.30 0.41 -0.37 -0.28 0.09 -0.88 -0.13 0.01 -0.25 0.19 0.25 0.30
9869 || orf19.6621 || MHP1 || || Protein similar to S. cerevisiae Mhp1p, which is involved in microtubule stabilization; transposon mutation affects filamentous growth; possibly transcriptionally regulated upon hyphal formation; possibly an essential gene (by UAU1 method) || 1 -0.14 -0.08 0.39 -0.27 0.68 0.19 -0.14 -0.38 -0.04 -0.82 -0.28 -0.14 -0.30 -0.31 0.27 0.31
9870 || orf19.7449 || || || Ortholog(s) have role in mitochondrial genome maintenance, plasmid maintenance and cytosol, mitochondrion localization || 1 -0.08 -0.09 0.26 0.05 0.09 0.49 -0.17 -0.20 -0.13 -0.49 -0.40 0.11 -0.18 -0.17 0.13 0.49
9871 || orf19.7225 || || || Ortholog of C. dubliniensis CD36 : Cd36_13150, C. parapsilosis CDC317 : CPAR2_700610, Candida tenuis NRRL Y-1498 : CANTEDRAFT_135418 and Debaryomyces hansenii CBS767 : DEHA2B01298g || 1 -0.11 -0.28 0.33 0.43 0.77 1.11 -0.06 -0.20 -0.49 -0.58 -1.00 0.25 -0.65 0.06 0.06 0.53
9872 || orf19.4893 || || || Ortholog of C. dubliniensis CD36 : Cd36_09630, C. parapsilosis CDC317 : CPAR2_805080, Candida tenuis NRRL Y-1498 : CANTEDRAFT_136811 and Debaryomyces hansenii CBS767 : DEHA2B12364g || 1 0.07 -0.09 0.13 -0.21 0.43 0.38 -0.04 -0.34 0.13 -0.56 -0.23 0.28 0.25 0.06 0.44 0.21
9873 || orf19.6005 || HGT5 || || Putative glucose transporter of the major facilitator superfamily; the C. albicans glucose transporter family comprises 20 members; 12 probable membrane-spanning segments, extended N terminus; expressed in rich medium; Hap43p-repressed || 1 -0.28 -0.34 0.12 -0.19 0.52 0.95 -0.31 -0.50 0.22 -0.48 -0.22 0.67 0.14 -0.07 0.50 0.02
9874 || orf19.6261 || BPH1 || || Ortholog of S. cerevisiae Bph1; a putative ortholog of human Chediak-Higashi syndrome protein and murine beige gene implicated in disease syndromes involving defective lysosomal trafficking; mutant is viable || 1 -0.28 -0.30 -0.09 -0.53 0.33 0.51 -0.08 -0.74 0.21 -0.87 -0.46 0.48 0.23 -0.41 -0.01 -0.02
9875 || orf19.744 || GDB1 || || Putative glycogen debranching enzyme; expression is regulated upon white-opaque switch; regulated by Nrg1, Tup1; rat catheter biofilm repressed || 1 -0.55 -0.71 -0.16 -0.43 0.02 0.54 -0.83 -1.24 -0.52 -1.28 -0.49 0.01 0.28 -0.46 0.51 -0.23
9876 || orf19.744 || GDB1 || || Putative glycogen debranching enzyme; expression is regulated upon white-opaque switch; regulated by Nrg1, Tup1; rat catheter biofilm repressed || 1 -0.50 -0.69 -0.15 -0.46 0.09 0.63 -0.46 -1.30 -0.45 -1.22 -0.25 0.21 0.35 -0.48 0.72 0.03
9877 || orf19.744 || GDB1 || || Putative glycogen debranching enzyme; expression is regulated upon white-opaque switch; regulated by Nrg1, Tup1; rat catheter biofilm repressed || 1 -0.48 -0.57 -0.10 -0.30 0.17 0.84 -0.60 -0.90 -0.26 -0.93 -0.23 0.48 0.54 -0.20 0.84 0.04
9878 || orf19.744 || GDB1 || || Putative glycogen debranching enzyme; expression is regulated upon white-opaque switch; regulated by Nrg1, Tup1; rat catheter biofilm repressed || 1 -0.73 -0.80 0.09 -0.05 -0.07 0.78 -0.63 -1.02 -0.31 -1.00 -0.35 0.36 0.29 -0.31 0.60 -0.01
9879 || orf19.744 || GDB1 || || Putative glycogen debranching enzyme; expression is regulated upon white-opaque switch; regulated by Nrg1, Tup1; rat catheter biofilm repressed || 1 -0.85 -0.85 -0.20 -0.79 0.05 0.77 -0.64 -1.13 -0.26 -0.97 -0.25 0.37 0.49 -0.01 0.55 -0.24
9880 || orf19.5605 || || || Ortholog(s) have protein binding, bridging, ubiquitin protein ligase binding activity and role in positive regulation of ubiquitin-dependent endocytosis, regulation of intracellular transport || 1 -0.89 -0.81 -0.49 -0.32 0.66 0.95 -0.46 -1.65 -0.41 -0.93 0.10 0.17 -0.09 -0.41 0.64 0.50
9881 || orf19.1576 || || || Ortholog(s) have nuclear localization sequence binding, ubiquitin binding activity, role in response to ethanol and cytosol localization || 1 -0.06 -0.30 -0.28 -0.48 0.31 0.69 -0.16 -0.43 -0.22 -0.17 -0.29 -0.10 0.16 -0.04 0.36 -0.09
9882 || orf19.4906 || || || Putative adhesin-like protein; positively regulated by Tbf1; Spider biofilm induced || 1 -0.32 -0.35 -0.47 -0.70 0.62 1.19 -0.50 -1.00 -0.46 -0.73 -0.71 0.07 0.74 -0.18 0.50 -0.05
9883 || orf19.5326 || || || Putative transcription factor with zinc finger DNA-binding motif; possible ortholog of S. cerevisiae Mig2p || 1 -0.14 -0.07 0.31 -0.46 0.42 1.39 -0.33 -0.74 -0.47 -0.78 -0.67 -0.14 0.81 -0.75 0.19 0.30
9884 || orf19.5326 || || || Putative transcription factor with zinc finger DNA-binding motif; possible ortholog of S. cerevisiae Mig2p || 1 -0.14 -0.14 0.30 -0.68 0.05 1.46 -0.17 -0.87 -0.35 -0.57 -0.73 0.31 0.46 -0.07 0.43 0.60
9885 || orf19.1149 || MRF1 || || Putative mitochondrial respiratory protein; induced by farnesol, benomyl, nitric oxide, core stress response; oxidative stress-induced via Cap1; stationary-phase enriched protein; Spider biofilm induced || 1 -1.42 -1.44 -0.58 -0.55 0.20 1.75 -0.27 -1.27 0.28 -0.83 -1.02 0.33 0.26 -1.18 0.63 -0.16
9886 || orf19.1149 || MRF1 || || Putative mitochondrial respiratory protein; induced by farnesol, benomyl, nitric oxide, core stress response; oxidative stress-induced via Cap1; stationary-phase enriched protein; Spider biofilm induced || 1 -0.95 -0.77 -0.33 0.51 0.43 1.51 -0.11 -1.07 0.64 -0.48 -1.11 0.00 0.70 -1.10 0.47 -1.03
9887 || orf19.3402 || FPG1 || || Formamidopyrimidine DNA glycosylase, involved in repair of gamma-irradiated DNA; Hap43p-repressed gene || 1 -0.63 -0.62 -0.25 -0.61 0.39 0.72 -0.22 -0.24 0.12 -0.31 0.17 0.48 0.32 -0.44 0.31 -0.18
9888 || orf19.2583.1 || || || Pseudogene; formerly an ORF Predicted by Annotation Working Group || 1 -0.89 -0.82 -0.20 -1.11 0.32 -0.18 -0.60 -0.42 0.22 -0.35 0.16 -0.27 -0.04 -0.35 0.00
9889 || orf19.3888.2 || || || Dubious open reading frame || 1 -0.75 -1.54 0.37 -0.54 0.09 0.27 -0.64 -0.24 -0.95 -0.35 0.29 0.17 -0.78 -0.70 -0.10 0.25
9890 || orf19.6532 || || || Ortholog(s) have FAD transmembrane transporter activity, role in FAD transport and mitochondrion localization || 1 -0.82 -0.96 -0.86 -0.52 0.17 0.47 0.27 -0.12 -0.30 -0.70 -0.10 0.51 -0.43 -0.79 -0.42 0.14
9891 || orf19.374 || || || Ortholog(s) have role in protein targeting to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway || 1 -0.33 -0.32 -0.18 -0.02 0.08 0.14 -0.11 -0.19 -0.08 -0.42 -0.40 -0.08 -0.27 -0.20 0.32 0.25
9892 || orf19.5251 || ZCF30 || || Predicted Zn(II)2Cys6 transcription factor; mutants are viable; repressed by fluphenazine; Spider biofilm induced || 1 -0.09 -0.45 -0.25 -0.10 -0.03 0.04 -0.18 -0.22 0.01 -0.36 -0.55 0.00 -0.23 -0.11 0.20 0.11
9893 || orf19.2579 || || || Msh4 ortholog of S. cerevisiae; involved in meiotic recombination and is required for normal levels of crossing over; Spider biofilm induced || 1 -0.63 -0.51 -0.20 -0.53 -0.03 0.55 -0.40 -0.71 0.27 -0.60 -0.83 0.25 -0.35 -0.01 0.51 0.24
9894 || orf19.1667 || || || Protein with a predicted SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily domain; Hap43-repressed gene || 1 -0.53 -0.34 -0.54 -0.81 0.06 0.47 0.19 -0.26 0.17 -0.49 -0.81 0.38 -0.44 -0.15 0.47 0.34
9895 || orf19.3919 || || || RNI-like superfamily domain-containing protein; early-stage flow model biofilm induced; Spider biofilm induced || 1 -0.49 -0.57 -0.09 -0.68 -0.15 0.41 0.10 -0.20 0.37 -0.58 -0.64 -0.14 -0.06 -0.25 0.25 0.14
9896 || orf19.698 || || || Integral ER membrane protein; predicted role in maintenance of ER zinc homeostasis; Spider biofilm induced || 1 -0.53 -0.52 -0.36 -0.62 -0.05 -0.14 -0.25 -0.32 0.26 0.06 -0.48 -0.41 0.05 0.09 0.09 -0.08
9897 || orf19.862 || || || Protein of unknown function; Spider biofilm induced || 1 -0.30 -0.46 -0.15 -0.34 0.37 0.14 -0.76 -0.73 0.03 -0.55 -0.36 -0.17 0.11 -0.13 0.04 -0.17
9898 || orf19.6897 || || || Protein of unknown function || 1 -0.28 -0.10 -0.09 -0.34 0.19 0.25 -0.36 -0.20 -0.29 -0.30 -0.27 -0.17 -0.03 0.08 -0.11 -0.22
9899 || orf19.4697 || MDN1 || || Putative midasin, a very large dynein-related AAA-type ATPase; induced during the mating process || 1 -0.42 -0.33 -0.57 -0.45 0.34 0.46 -0.73 -0.72 -0.58 -0.02 -0.76 -0.56 0.06 0.01 -0.22 -0.06
9900 || orf19.6139 || FRE7 || || Copper-regulated cupric reductase; repressed by ciclopirox olamine or 17-beta-estradiol; induced by alkaline conditions or interaction with macrophage; Spider biofilm induced || 1 -0.68 -0.76 -0.89 -0.75 0.13 0.78 -0.87 -0.55 -0.20 -0.89 -0.88 -0.22 0.27 0.56 0.43 0.28
9901 || orf19.1263 || CFL1 || || Protein similar to ferric reductase Fre10p; possible functional homolog of S. cerevisiae Fre1p (reports differ); transcription is negatively regulated by Sfu1p, copper, amphotericin B, caspofungin; induced by ciclopirox olamine || 1 -0.93 -0.83 -0.35 -1.01 0.19 0.01 -0.76 -0.55 0.10 -0.75 -0.56 -0.41 0.21 0.23 -0.06 0.19
9902 || orf19.1263 || CFL1 || || Protein similar to ferric reductase Fre10p; possible functional homolog of S. cerevisiae Fre1p (reports differ); transcription is negatively regulated by Sfu1p, copper, amphotericin B, caspofungin; induced by ciclopirox olamine || 1 -0.79 -0.95 -0.62 -0.99 0.41 0.42 -0.40 -0.51 -0.34 -0.87 -0.45 -0.46 0.03 0.14 -0.09 0.15
9903 || orf19.4222 || SST2 || || Predicted regulator of G-protein signaling in mating pathway; null mutation causes alpha-factor hypersensitivity and mating defect (in opaque MTLa/MTLa background); transcript induced by alpha factor || 1 -0.79 -1.20 -1.13 -1.23 0.05 0.16 -0.85 -0.87 -0.49 -0.79 -1.16 -0.59 -0.48 0.56 -0.62 -0.06
9904 || orf19.1722 || || || Ortholog of Candida albicans WO-1 : CAWG_02462 || 1 -0.74 -0.48 -1.13 -0.80 0.37 -0.09 -0.53 -0.40 0.16 -0.85 -0.52 -0.29 -0.04 -0.27 -0.28 -0.08
9905 || orf19.5236 || || || Ortholog(s) have dehydrodolichyl diphosphate synthase activity, role in protein glycosylation and lipid particle localization || 1 -0.88 -0.95 -1.81 -2.01 0.50 -0.33 -0.41 -0.17 0.21 -0.15 -0.64 -0.41 -0.22 -0.07 -0.44 -0.39
9906 || orf19.2978 || || || Protein of unknown function; Hap43-repressed gene || 1 -1.15 -1.13 -1.62 -1.85 0.49 0.34 -0.05 0.11 -0.28 -0.74 -0.66 -0.61 0.05 0.53 0.31 -0.55
9907 || orf19.2978 || || || Protein of unknown function; Hap43-repressed gene || 1 -1.01 -1.11 -1.26 -1.21 0.50 0.46 -0.04 0.33 0.19 -0.50 -0.48 -0.81 0.13 0.18 0.17 -0.67
9908 || orf19.4883 || || || Protein of unknown function; S. cerevisiae ortholog Cos111 confers resistance to the antifungal drug ciclopirox olamine; constitutive expression independent of MTL or white-opaque status; Spider biofilm induced || 1 -1.91 -1.40 -0.67 -0.84 0.23 0.83 0.26 -0.80 0.37 -0.42 -1.55 -0.13 0.08 0.58 1.02 -0.29
9909 || orf19.4883 || || || Protein of unknown function; S. cerevisiae ortholog Cos111 confers resistance to the antifungal drug ciclopirox olamine; constitutive expression independent of MTL or white-opaque status; Spider biofilm induced || 1 -1.72 -1.52 -0.88 -0.95 0.09 0.37 0.22 -0.96 0.35 -0.52 -1.92 -0.55 0.07 0.10 0.97 -0.27
9910 || orf19.6888 || || || Zn(II)2Cys6 domain transcription factor; regulated by Mig1 and Tup1; rat catheter and Spider biofilm induced || 1 -1.87 -2.33 -1.40 -1.21 -0.54 0.44 0.18 -0.88 0.35 -0.89 -1.21 -0.55 0.09 0.45 0.44 -0.20
9911 || orf19.6139 || FRE7 || || Copper-regulated cupric reductase; repressed by ciclopirox olamine or 17-beta-estradiol; induced by alkaline conditions or interaction with macrophage; Spider biofilm induced || 1 -1.79 -2.10 -1.15 -1.47 0.22 0.65 -0.65 -0.31 0.34 -0.55 -1.17 -0.22 -1.09 0.29 0.71 -0.16
9912 || orf19.6139 || FRE7 || || Copper-regulated cupric reductase; repressed by ciclopirox olamine or 17-beta-estradiol; induced by alkaline conditions or interaction with macrophage; Spider biofilm induced || 1 -2.12 -1.97 -1.09 -0.63 0.23 1.44 -0.60 -0.54 0.08 -0.71 -0.95 -0.03 -0.69 0.15 0.45 -0.10
9913 || orf19.6508 || || || Ortholog(s) have protein transporter activity, role in Golgi to plasma membrane transport, intracellular protein transport and vesicle coat localization || 1 -1.10 -1.02 -0.65 -0.31 0.43 0.04 -0.44 -0.50 -0.16 -0.04 -0.46 0.24 -0.51 0.02 -0.05 -0.01
9914 || orf19.4114 || FAA2-1 || || Predicted long chain fatty acid CoA ligase; upregulated upon phagocytosis; induced by nitric oxide independent of Yhb1 || 1 -0.88 -0.91 -0.75 -0.38 0.18 0.09 -0.39 -0.33 0.12 0.17 -0.75 -0.13 -0.91 -0.24 0.27 -0.52
9915 || orf19.717 || HSP60 || || Heat shock protein; soluble in hyphae; regulated by Nrg1 and by iron; induced in high iron; heavy metal (cadmium) stress-induced; sumoylation target; protein present in exponential and stationary phase cells; Hap43-repressed || 1 -1.59 -1.63 -1.96 -1.67 0.23 0.43 -0.54 -0.61 0.09 -0.19 -1.11 -0.41 -1.38 -0.55 -0.06 -0.84
9916 || orf19.717 || HSP60 || || Heat shock protein; soluble in hyphae; regulated by Nrg1 and by iron; induced in high iron; heavy metal (cadmium) stress-induced; sumoylation target; protein present in exponential and stationary phase cells; Hap43-repressed || 1 -1.08 -1.11 -1.25 -1.30 0.69 0.52 -0.14 -0.14 0.43 0.16 -0.66 -0.49 -1.15 -0.56 -0.08 -0.64
9917 || orf19.5439 || || || Ortholog of C. parapsilosis CDC317 : CPAR2_504010, C. dubliniensis CD36 : Cd36_80270, Lodderomyces elongisporus NRLL YB-4239 : LELG_02294 and Pichia stipitis Pignal : PICST_29581 || 1 -0.66 -0.69 -0.84 -0.69 0.34 0.61 -0.13 -0.56 0.05 -0.14 -0.43 0.04 -0.92 0.29 -0.06 -0.60
9918 || orf19.4097 || || || Ortholog of C. dubliniensis CD36 : Cd36_23480, C. parapsilosis CDC317 : CPAR2_407050, Candida tenuis NRRL Y-1498 : CANTEDRAFT_116822 and Debaryomyces hansenii CBS767 : DEHA2B02046g || 1 -1.02 -1.06 -1.22 -1.00 0.46 0.86 -0.44 -0.90 0.10 0.13 -1.05 0.05 -0.66 -0.05 0.34 -0.57
9919 || orf19.4097 || || || Ortholog of C. dubliniensis CD36 : Cd36_23480, C. parapsilosis CDC317 : CPAR2_407050, Candida tenuis NRRL Y-1498 : CANTEDRAFT_116822 and Debaryomyces hansenii CBS767 : DEHA2B02046g || 1 -0.68 -0.82 -1.08 -0.66 0.82 0.68 -0.37 -0.63 -0.24 0.47 -1.00 -0.11 -0.43 -0.06 0.40 -0.70
9920 || orf19.4114 || FAA2-1 || || Predicted long chain fatty acid CoA ligase; upregulated upon phagocytosis; induced by nitric oxide independent of Yhb1 || 1 -0.49 -0.54 -0.79 -0.40 0.59 0.49 -0.31 -0.04 -0.11 0.01 -0.47 0.15 -0.39 0.02 0.56 -0.19
9921 || orf19.5380 || LYS144 || || Zn(II)2Cys6 transcription factor; has similarity to S. cerevisiae Lys14, involved in the regulation of lysine biosynthesis genes || 1 -0.88 -0.75 -0.68 -1.21 0.49 0.46 -0.66 -0.56 0.04 -0.19 -0.32 0.54 -0.09 0.15 0.07 0.41
9922 || orf19.3523 || CRK1 || || Protein kinase of the Cdc2 subfamily involved in hyphal development, virulence; promotes hyphal development independently of Cph1 and Efg1; functionally complements pheromone hypersensitivity of S. cerevisiae sgv1 mutant; Hap43p-repressed || 1 -0.54 -0.74 -0.63 -0.90 0.01 0.38 -0.47 -0.67 0.05 0.03 -0.55 0.43 0.19 0.24 -0.44 0.43
9923 || orf19.3858 || || || Protein of unknown function; rat catheter and Spider biofilm induced || 1 -0.74 -0.51 -0.80 -0.70 -0.19 0.30 -0.49 -0.43 -0.56 0.00 0.11 0.25 0.28 0.04 -0.10 0.22
9924 || orf19.7073 || || || Ortholog of S. cerevisiae : YCL002C, C. glabrata CBS138 : CAGL0B04719g, C. dubliniensis CD36 : Cd36_70180, C. parapsilosis CDC317 : CPAR2_805360 and Candida tenuis NRRL Y-1498 : cten_CGOB_00114 || 1 -0.67 -0.47 -0.24 -0.30 -0.45 0.58 -0.43 -0.82 0.12 -0.33 0.09 -0.08 -0.51 0.70 -0.31 0.33
9925 || orf19.2026 || UBP13 || || Ortholog of S. cerevisiae Ubp13; putative ubiquitin carboxyl-terminal hydrolase; flow model biofilm induced; rat catheter biofilm repressed || 1 -0.27 -0.28 -0.25 -0.34 -0.17 0.19 -0.08 -0.37 -0.19 -0.29 -0.16 -0.19 -0.08 0.25 -0.23 0.30
9926 || orf19.669 || PRM1 || || Putative membrane protein with a predicted role in membrane fusion during mating; Hap43p-repressed gene; protein induced during the mating process || 1 -0.63 -0.52 -1.23 -1.09 -0.40 0.33 -0.50 -0.74 -0.26 -0.79 -0.08 -0.24 -0.53 0.60 -0.10 0.93
9927 || orf19.4403 || VPS11 || || Protein involved in protein trafficking; putative role in vesicle-target membrane fusion; mutant lacks vacuole; role in hyphal growth, possibly via vacuole expansion into hypha; role in killing of and survival within macrophage || 1 -0.26 -0.12 -0.54 -0.39 -0.41 -0.26 -0.76 -0.71 -0.31 -0.51 -0.70 0.01 -0.64 0.07 -0.03 -0.00
9928 || orf19.7164 || || || Ortholog(s) have role in ascospore formation, conidiophore development, conidium formation, response to oxidative stress, sporocarp development involved in sexual reproduction, vacuolar protein processing || 1 -0.26 -0.11 -0.23 -0.30 -0.15 0.05 -0.48 -0.64 -0.90 -0.11 -0.40 -0.25 -0.60 0.18 -0.33 0.23
9929 || orf19.1717 || || || Ortholog of C. dubliniensis CD36 : Cd36_81270, C. parapsilosis CDC317 : CPAR2_502880, Candida tenuis NRRL Y-1498 : CANTEDRAFT_101483 and Debaryomyces hansenii CBS767 : DEHA2A11990g || 1 -0.20 -0.13 0.06 -0.41 -0.30 0.20 -0.41 -0.35 -0.54 -0.10 -0.44 -0.08 -0.80 -0.18 -0.12 -0.04
9930 || orf19.5828 || || || Ortholog(s) have pre-mRNA branch point binding activity, role in generation of catalytic spliceosome for first transesterification step, mRNA branch site recognition, mRNA cis splicing, via spliceosome and commitment complex localization || 1 -0.21 -0.23 -0.17 -0.50 0.17 0.10 -0.15 -0.06 -0.11 -0.29 -0.24 0.02 -0.41 -0.04 -0.30 0.09
9931 || orf19.3819 || || || Protein of unknown function; transcript detected on high-resolution tiling arrays || 1 -0.30 -0.40 -0.14 -0.36 -0.13 0.25 -0.31 -0.20 -0.35 -0.50 -0.19 -0.15 -0.63 0.02 -0.49 0.04
9932 || orf19.4191.1 || || || Ortholog(s) have ubiquitin-ubiquitin ligase activity, role in ER-associated ubiquitin-dependent protein catabolic process, protein polyubiquitination and cytosol, nuclear envelope, proteasome complex localization || 1 -0.06 -0.38 -0.08 -0.20 0.05 -0.07 -0.39 -0.17 -0.06 -0.47 -0.43 0.00 -0.44 0.07 -0.31 0.19
9933 || orf19.2186 || SEH1 || || Ortholog(s) have Seh1-associated complex, cytosol, fungal-type vacuole membrane, nuclear membrane, nuclear pore outer ring localization || 1 -0.10 -0.19 -0.27 -0.19 -0.35 -0.07 -0.49 -0.34 -0.22 -0.62 -0.14 0.05 -0.66 0.02 -0.61 0.07
9934 || orf19.6011 || SIN3 || || Protein similar to S. cerevisiae Sin3p (transcriptional corepressor involved in histone deacetylase recruitment); has paired amphipathic helix PAH1 domain; interacts with ScOpi1p, not CaOpi1p; transposon mutation affects filamentous growth || 1 -0.14 -0.04 -0.22 -0.01 -0.15 -0.05 -0.38 -0.34 -0.18 -0.66 -0.19 -0.07 -0.32 0.07 -0.23 0.07
9935 || orf19.333 || FCY2 || || Purine-cytosine permease of pyrimidine salvage; mutation associated with resistance to flucytosine in clinical isolates; transposon mutation affects filamentation; farnesol-upregulated in biofilm || 1 -0.94 -0.67 -1.49 -0.94 0.22 0.55 -1.27 -1.36 -1.08 -1.57 -0.39 -0.25 -0.28 -0.91 -0.93 0.18
9936 || orf19.333 || FCY2 || || Purine-cytosine permease of pyrimidine salvage; mutation associated with resistance to flucytosine in clinical isolates; transposon mutation affects filamentation; farnesol-upregulated in biofilm || 1 -0.60 -0.71 -0.66 -1.17 0.49 0.73 -1.34 -1.21 -1.05 -1.57 -0.08 0.16 -0.34 -0.51 -0.75 0.57
9937 || orf19.333 || FCY2 || || Purine-cytosine permease of pyrimidine salvage; mutation associated with resistance to flucytosine in clinical isolates; transposon mutation affects filamentation; farnesol-upregulated in biofilm || 1 -0.50 -0.63 -0.05 -0.77 0.18 0.56 -1.68 -1.50 -1.09 -1.62 -0.71 -0.25 -0.31 -1.02 -1.27 0.38
9938 || orf19.7405 || || || Ortholog of Rad33; involved in nucleotide excision repair in S. cerevisiae; induced by Mnl1 under weak acid stress || 1 -0.38 -0.23 -0.09 -0.39 0.04 0.16 -0.60 -0.47 -0.19 -1.09 -0.38 -0.51 -0.26 -0.17 -0.88 0.19
9939 || orf19.2108 || SOD6 || || Copper- and zinc-containing superoxide dismutase; gene family includes SOD1, SOD4, SOD5, and SOD6; gene may contain an intron; Hap43-repressed; flow model and rat catheter biofilm induced || 1 -0.50 -0.35 -0.27 -0.53 -0.16 0.41 -1.14 -1.40 -0.17 -1.49 -0.51 -0.08 -0.90 -0.32 -0.88 1.66
9940 || orf19.1563 || ECM3 || || Ortholog(s) have endoplasmic reticulum localization || 1 -0.29 -0.46 -0.08 -0.38 -0.28 0.08 -0.39 -0.70 -0.06 -0.64 -0.16 -0.06 -0.09 -0.50 -0.41 0.40
9941 || orf19.1978 || GIT2 || || Putative glycerophosphoinositol permease; fungal-specific; repressed by alpha pheromone in SpiderM medium; Hap43-repressed; Spider biofilm induced || 1 -0.60 -0.58 0.07 -0.57 -0.84 0.19 -1.29 -1.49 -1.40 -1.44 -0.03 0.58 -0.60 -0.20 -0.38 0.70
9942 || orf19.1978 || GIT2 || || Putative glycerophosphoinositol permease; fungal-specific; repressed by alpha pheromone in SpiderM medium; Hap43-repressed; Spider biofilm induced || 1 -1.33 -1.33 -0.30 -1.62 -1.63 -0.19 -2.42 -2.32 -1.89 -1.29 -0.41 0.65 -0.91 -0.53 -0.59 0.89
9943 || orf19.6481 || YPS7 || || Putative aspartic-type endopeptidase with limited ability to degrade alpha pheromone; mutants show increased sensitivity to alpha pheromone || 1 -0.36 -0.52 -0.02 -0.49 -0.33 -0.30 -1.14 -0.50 -0.60 -0.40 0.02 -0.31 -0.29 0.07 -0.17 0.20
9944 || orf19.5442 || || || Ortholog of C. dubliniensis CD36 : Cd36_80240, C. parapsilosis CDC317 : CPAR2_504040, Candida tenuis NRRL Y-1498 : CANTEDRAFT_130872 and Debaryomyces hansenii CBS767 : DEHA2C06006g || 1 -0.59 -0.72 -0.34 -0.41 -0.45 -0.39 -0.73 -0.61 -0.63 -0.01 -0.05 -0.27 -0.65 -0.09 -0.50 0.32
9945 || orf19.5390 || || || Ortholog of Candida albicans WO-1 : CAWG_02403 || 1 -0.77 -0.84 -0.37 -0.56 -0.04 -0.31 -0.73 -0.66 -0.56 -0.47 0.05 -0.19 -0.21 0.01 -0.22 0.67
9946 || orf19.321 || || || Ortholog(s) have L-methionine transmembrane transporter activity and role in methionine import || 1 -0.48 -0.42 -0.27 -0.23 -0.21 -0.35 -0.39 -0.33 -0.34 -0.50 0.20 0.02 -0.44 -0.22 -0.31 0.89
9947 || orf19.2670 || || || Ortholog(s) have 3-hydroxyacyl-[acyl-carrier-protein] dehydratase activity, role in fatty acid biosynthetic process and mitochondrion localization || 1 -0.19 -0.27 -0.66 -0.55 -0.34 -0.12 -0.42 -0.38 -0.44 -1.14 0.10 -0.19 -0.74 -0.35 -0.47 0.79
9948 || orf19.4595 || || || Ortholog of C. dubliniensis CD36 : Cd36_41860, C. parapsilosis CDC317 : CPAR2_400440, Candida tenuis NRRL Y-1498 : CANTEDRAFT_103033 and Debaryomyces hansenii CBS767 : DEHA2B03234g || 1 -0.61 -0.60 -0.51 -0.88 -0.78 -0.47 -0.72 -0.59 -0.58 -0.99 -0.22 -0.01 -0.86 -0.06 -0.68 0.86
9949 || orf19.5318 || RAD1 || || Putative single-stranded DNA endonuclease; transcript regulated by Nrg1; macrophage-induced gene || 1 -0.32 -0.52 -0.51 -0.92 -0.47 -0.22 -0.15 -0.57 -0.35 -0.58 -0.07 0.01 -0.51 0.03 -0.47 0.50
9950 || orf19.1009 || || || Ortholog of Candida albicans WO-1 : CAWG_01857 || 1 -0.39 0.16 -0.69 -1.19 -0.60 -0.16 -1.07 -1.27 -1.50 -0.93 0.05 -0.84 -0.59 0.03 -1.02 1.49
9951 || orf19.7096 || || || Ortholog(s) have fungal-type vacuole membrane, mitochondrion localization || 1 -0.36 -0.34 0.07 -0.12 -0.11 -0.02 -0.19 -0.31 -0.30 -0.31 -0.14 0.18 -0.17 0.05 -0.29 0.57
9952 || orf19.4288 || CTA7 || || Zn(II)2Cys6 transcription factor; activates transcription in 1-hybrid assay in S. cerevisiae; has similarity to S. cerevisiae Stb4 || 1 -0.36 -0.51 0.06 -0.28 -0.14 0.04 -0.46 -0.44 0.08 -0.12 -0.15 -0.06 -0.33 -0.16 -0.23 0.71
9953 || orf19.3888 || PGI1 || || Glucose-6-phosphate isomerase; enzyme of glycolysis; antigenic; Efg1-regulated; induced upon adherence to polystyrene; repressed by phagocytosis, human neutrophils; flow model biofilm induced; rat catheter and Spider biofilm repressed || 1 -0.75 -0.78 -0.22 -0.64 -0.53 0.26 -0.60 -0.67 -0.38 -1.51 -0.30 -0.38 0.16 -0.53 -0.41 -0.16
9954 || orf19.6660 || || || Protein of unknown function; mRNA binds to She3; Hap43-repressed; rat catheter and flow model biofilm induced || 1 -0.89 -0.87 -1.34 -0.96 -0.04 0.24 -0.06 -0.41 -1.23 -1.50 0.78 -0.91 -0.76 -0.94 -0.32 -0.25
9955 || orf19.5040 || || || Ortholog(s) have nucleocytoplasmic transporter activity, phospholipid binding, single-stranded DNA binding activity || 1 0.07 -0.18 -0.48 -0.54 0.40 0.27 -0.08 -0.31 -0.63 -0.21 0.03 0.06 -0.09 -0.52 0.72 0.33
9956 || orf19.4756 || || || Ortholog of S. cerevisiae : YTP1, C. dubliniensis CD36 : Cd36_08490, C. parapsilosis CDC317 : CPAR2_801590, Candida tenuis NRRL Y-1498 : CANTEDRAFT_109732 and Debaryomyces hansenii CBS767 : DEHA2C10384g || 1 0.15 0.03 -0.48 -0.37 0.08 0.29 -0.48 -0.51 -0.35 -0.15 -0.02 0.40 -0.24 -0.55 0.31 0.35
9957 || orf19.7523 || MKC1 || || MAP kinase; role in biofilm formation, contact-induced invasive filamentation, systemic virulence in mouse, cell wall structure/maintenance, caspofungin response; phosphorylated on surface contact, membrane perturbation, or cell wall stress || 1 -0.09 -0.07 -0.64 -0.43 -0.03 -0.07 -0.88 -0.59 -0.82 -0.21 -0.07 -0.04 -0.32 -0.90 0.37 0.14
9958 || orf19.2674 || || || Putative transcription factor with zinc finger DNA-binding motif; Hap43p-repressed gene || 1 -0.31 -0.10 -1.11 -0.77 0.45 -0.17 -0.68 -0.28 -0.81 -0.89 0.44 0.19 -0.08 -0.49 0.29 0.16
9959 || orf19.881 || DFG16 || || Rim101 pathway protein that acts in Rim101 processing; regulates filamentation in response to alkaline pH; required for host tissue invasion during infection; flow model biofilm induced || 1 -0.00 0.02 -0.12 -0.21 0.53 0.42 -0.23 -0.17 -0.07 -0.62 0.01 -0.07 -0.18 -0.29 0.43 0.72
9960 || orf19.2655 || BUB3 || || Protein similar to S. cerevisiae Bub3; a kinetochore checkpoint component; induced by hydroxyurea treatment; flow model biofilm induced; Spider biofilm induced || 1 -0.22 -0.20 -0.11 -0.39 0.74 0.79 -0.68 -0.98 -0.06 -1.20 0.34 -0.20 -0.45 -0.27 0.45 0.97
9961 || orf19.2655 || BUB3 || || Protein similar to S. cerevisiae Bub3; a kinetochore checkpoint component; induced by hydroxyurea treatment; flow model biofilm induced; Spider biofilm induced || 1 0.31 0.13 0.12 -0.33 0.53 0.48 -0.52 -0.76 -0.37 -1.45 0.11 -0.38 -0.07 -0.60 0.38 0.84
9962 || orf19.3412 || ATG15 || || Putative lipase; fungal-specific (no human or murine homolog); Hap43p-repressed gene || 1 -0.12 -0.20 -0.35 -0.15 0.50 0.46 -0.62 -0.79 -0.85 -1.10 0.21 -0.28 -0.25 -0.44 0.78 0.69
9963 || orf19.6979 || || || Ortholog(s) have role in cellular manganese ion homeostasis, mitochondrion organization and fungal-type vacuole membrane localization || 1 -0.19 -0.09 -0.29 -0.20 0.29 0.38 -0.72 -0.86 -0.94 -0.71 0.54 0.02 -0.21 -0.61 0.89 0.56
9964 || orf19.5671 || || || Ortholog(s) have role in actin cortical patch assembly, septin cytoskeleton organization and cellular bud neck, cellular bud tip, mating projection base, mating projection tip localization || 1 -0.35 -0.29 -0.19 -0.39 0.41 0.05 -0.48 -0.12 -0.56 -0.67 0.10 -0.14 -0.15 -0.07 0.55 0.16
9965 || orf19.699 || || || Protein of unknown function; flow model, rat catheter, Spider biofilm induced || 1 -0.54 -1.78 -2.24 -0.97 2.67 2.49 -0.74 -0.88 -3.02 -5.20 -0.45 -0.64 -0.87 -0.86 1.97 0.78
9966 || orf19.4439 || || || Ortholog of Candida albicans WO-1 : CAWG_00687 || 1 -0.12 -0.41 -1.23 -0.05 0.44 0.32 -0.73 -0.75 -1.45 -1.08 -0.34 -0.23 -0.33 0.28 0.29
9967 || orf19.7078 || || || Ortholog(s) have role in meiosis and cytoplasm localization || 1 -0.35 -0.35 -0.95 -0.28 0.83 0.96 -1.23 -0.58 -0.74 -1.18 -0.15 -0.68 -0.69 -0.46 0.53 -0.39
9968 || orf19.1257 || || || Ortholog of Candida albicans WO-1 : CAWG_03251 || 1 -0.32 -0.78 -0.39 -1.26 1.12 1.53 -0.66 -0.48 -2.47 -1.53 0.64 -0.06 -0.32 -0.60 -0.16 0.54
9969 || orf19.5634 || FRP1 || || Ferric reductase; alkaline-induced by Rim101; iron-chelation-induced by CCAAT-binding factor; fluconazole-repressed; ciclopirox-, hypoxia-, Hap43-induced; colony morphology-related regulation by Ssn6; Spider and flow model biofilm induced || 1 -0.65 -0.89 -1.20 -1.21 0.09 0.85 -0.80 -0.01 -1.37 -1.57 0.16 -0.66 0.28 0.31 0.53 1.44
9970 || orf19.1220 || RVS167 || || SH3-domain- and BAR domain-containing protein involved in endocytosis; null mutant exhibits defects in hyphal growth, virulence, cell wall integrity, and actin patch localization; cosediments with phosphorylated Myo5p || 1 -0.18 -0.32 -0.54 -0.55 -0.09 0.04 -0.09 -0.29 -0.52 -0.80 -0.09 -0.35 -0.16 -0.05 0.54 0.22
9971 || orf19.5489 || || || Ortholog of C. dubliniensis CD36 : Cd36_20660, C. parapsilosis CDC317 : CPAR2_104730, Candida tenuis NRRL Y-1498 : CANTEDRAFT_133951 and Debaryomyces hansenii CBS767 : DEHA2F02068g || 1 -0.55 -0.28 -0.61 -1.15 -0.25 -0.08 -0.18 -0.55 0.16 -0.43 0.13 0.08 -0.16 -1.08 0.33 0.04
9972 || orf19.3656 || COX15 || || Cytochrome oxidase assembly protein; transcript regulated by Nrg1 and Tup1; alkaline repressed; Hap43-repressed; early-stage flow model biofilm induced; Spider biofilm repressed || 1 -0.60 -0.62 -0.76 -1.32 -0.16 0.21 -0.36 -0.31 0.39 -0.55 -0.10 0.22 -0.87 -0.88 -0.01 0.27
9973 || orf19.3656 || COX15 || || Cytochrome oxidase assembly protein; transcript regulated by Nrg1 and Tup1; alkaline repressed; Hap43-repressed; early-stage flow model biofilm induced; Spider biofilm repressed || 1 -0.66 -0.83 -0.84 -1.76 -0.33 0.09 -0.41 -0.32 0.18 -0.76 -0.21 -0.23 -0.96 -1.31 -0.33 -0.41
9974 || orf19.4024 || RIB5 || || Putative riboflavin synthase; fungal-specific (no human or murine homolog); farnesol-downregulated; protein present in exponential and stationary growth phase yeast cultures || 1 -0.25 -0.28 -0.57 -0.79 -0.03 0.33 -0.07 -0.24 -0.19 -0.35 -0.12 0.20 -0.44 -0.24 0.36 -0.06
9975 || orf19.1939 || || || Ortholog of S. cerevisiae : YDR374C, C. glabrata CBS138 : CAGL0A02970g, C. dubliniensis CD36 : Cd36_51030, C. parapsilosis CDC317 : CPAR2_303320 and Candida tenuis NRRL Y-1498 : CANTEDRAFT_106457 || 1 -0.46 -0.63 -0.78 -3.25 0.05 0.83 -0.49 -0.33 -0.49 -0.73 -0.11 0.79 -0.81 -1.26 0.48 0.60
9976 || orf19.2899 || || || Ortholog(s) have cytosol, nucleus localization || 1 -0.31 -0.74 -0.97 -2.66 0.57 1.63 -0.31 -0.75 -0.38 0.19 0.55 1.05 -1.47 -1.74 0.43
9977 || orf19.5362 || PSO2 || || Putative DNA cross-link repair protein; expressed in opaque or white MTLa/MTLa or MTLalpha/MTLalpha, but not MTLa/MTLalpha cells; telomere-proximal gene; mutation does not affect white-to-opaque phenotypic switching || 1 -0.50 -0.26 -0.43 -0.73 0.50 0.78 -0.21 -0.31 0.33 -0.32 -0.50 0.01 -0.56 -0.36 -0.53 0.20
9978 || orf19.353 || ULP1 || || SUMO deconjugation enzyme that cleaves the small ubiquitin-like modifier (SUMO) off proteins || 1 -0.25 -0.26 -0.81 -1.45 0.66 1.11 -0.71 -0.71 -0.66 -0.64 -0.02 -0.23 -0.90 -0.38 -0.56 -0.06
9979 || orf19.4786 || FGR43 || || Protein lacking an S. cerevisiae ortholog; transposon mutation affects filamentous growth; induced by by Mnl1 under weak acid stress || 1 -0.97 -0.97 -1.04 -1.35 1.05 1.49 -0.68 -0.63 -0.31 -0.44 0.36 0.19 -0.64 -0.86 -0.57 0.17
9980 || orf19.4786 || FGR43 || || Protein lacking an S. cerevisiae ortholog; transposon mutation affects filamentous growth; induced by by Mnl1 under weak acid stress || 1 -1.74 -1.72 -1.57 -1.78 0.92 1.51 -1.03 -0.83 -0.53 -0.52 0.18 0.12 -1.72 -1.05 -1.48 0.09
9981 || orf19.4519 || SUV3 || || RNA helicase; mitochondrial RNA catabolism; required for chlamydospore formation, embedded hyphal growth, wild-type respiratory growth, alkaline-induced morphogenesis and SD or Spider biofilm formation; rat catheter biofilm induced || 1 -0.87 -0.90 -1.18 -1.32 0.64 0.67 -0.28 -0.61 -0.75 0.27 0.01 -0.07 -0.44 -0.55 -0.38 -0.21
9982 || orf19.5163 || SFI1 || || Putative centrin-binding protein; predicted role in spindle pole body duplication; induced by alpha pheromone in SpiderM medium; essential for growth || 1 -0.33 -0.16 -0.19 -0.35 0.62 -0.04 -0.23 -0.47 -0.44 -0.34 -0.07 -0.03 -0.46 -0.37 0.23 -0.28
9983 || orf19.7124 || RVS161 || || Protein required for endocytosis; contains a BAR domain, which is found in proteins involved in membrane curvature; null mutant exhibits defects in hyphal growth, virulence, cell wall integrity, and actin patch localization || 1 -0.32 -0.28 -0.19 -0.46 0.22 0.09 -0.41 -0.54 -0.44 -0.54 -0.19 -0.14 -0.81 -0.22 0.36 -0.63
9984 || orf19.4542 || || || Ortholog(s) have cyclin-dependent protein serine/threonine kinase inhibitor activity and role in phosphorylation of RNA polymerase II C-terminal domain, regulation of mitotic cell cycle, transcription from RNA polymerase II promoter || 1 -0.20 -0.27 -0.51 -0.32 -0.15 0.11 -0.48 -0.36 -0.63 -0.56 0.07 0.11 -0.26 -0.09 0.23 -0.47
9985 || orf19.4952 || || || Protein of unknown function; flow model biofilm induced; Spider biofilm induced || 1 -0.18 -0.37 -0.52 -0.07 0.00 0.53 -0.49 -0.77 -0.82 -0.44 -0.31 0.08 -0.46 -0.41 0.74 -0.44
9986 || orf19.6597 || || || Ortholog(s) have cytoplasm localization || 1 -0.35 -0.40 -0.41 -0.54 -0.01 0.61 -0.62 -0.39 -0.88 0.19 0.07 0.09 -0.33 0.04 -0.37 0.09
9987 || orf19.2066 || || || Ortholog(s) have cytoplasm localization || 1 -0.78 -0.55 -0.48 -0.66 0.15 0.63 -0.73 -0.42 -1.18 0.39 -0.13 0.09 -0.46 -0.50 0.28 -0.00
9988 || orf19.5864 || URK1 || || Protein similar to uridine kinase; repressed by ciclopirox olamine; Spider biofilm induced || 1 -0.49 -0.74 -0.74 -1.05 0.20 0.39 -0.25 -0.82 -0.97 0.01 0.02 0.29 -0.62 -0.09 0.16 0.48
9989 || orf19.4062 || TRY2 || || Transcription factor; regulator of yeast form adherence; required for yeast cell adherence to silicone substrate; Spider biofilm induced || 1 -0.42 -0.42 -0.19 -0.78 0.20 -0.05 -0.23 -0.15 -0.50 -0.05 0.13 -0.02 -0.06 -0.15 -0.13 0.00
9990 || orf19.2485 || || || Ortholog(s) have structural constituent of nuclear pore activity and role in chromosome segregation, mitotic spindle assembly checkpoint, nuclear pore complex assembly, protein targeting to nuclear inner membrane || 1 -0.26 -0.20 -0.38 -0.57 0.05 -0.32 -0.30 -0.07 -0.39 -0.19 0.21 0.01 -0.06 0.10 -0.16 0.16
9991 || orf19.3647 || SEC8 || || Predicted subunit of the exocyst complex, involved in exocytosis; localizes to a crescent on the surface of the hyphal tip || 1 -0.40 -0.38 -0.81 -0.39 -0.10 -0.46 -0.53 -0.44 -0.52 -0.05 0.12 0.06 -0.50 -0.10 -0.17 0.31
9992 || orf19.1084 || CDC39 || || Protein similar to S. cerevisiae Cdc39p, which is part of the CCR4-NOT transcription regulatory complex; transposon mutation affects filamentous growth || 1 -0.39 -0.46 -0.57 -0.47 0.14 -0.31 -0.62 -0.44 -0.55 -0.35 0.03 0.16 -0.70 0.02 -0.07 -0.12
9993 || orf19.55 || || || Ortholog(s) have role in cellular zinc ion homeostasis and endoplasmic reticulum localization || 1 -0.67 -0.81 -0.95 -0.99 -0.47 -0.01 -0.85 -0.39 -1.09 -0.22 0.29 0.01 -0.72 0.24 -0.21 -0.01
9994 || orf19.748 || || || Ortholog(s) have RNA binding, nucleocytoplasmic transporter activity, structural constituent of nuclear pore activity || 1 -0.47 -0.48 -0.84 -0.77 -0.18 -0.16 -0.58 -0.70 -1.08 -0.23 -0.07 0.11 -0.72 -0.07 -0.37 -0.12
9995 || orf19.5832 || HPT1 || || Putative hypoxanthine-guanine phosphoribosyltransferase; protein abundance affected by URA3 expression in the CAI4 strain background; protein level decreases in stationary phase; Spider biofilm induced || 1 -0.81 -0.95 -1.17 -1.52 -0.38 0.12 -0.95 -0.81 -1.51 0.05 0.22 -0.26 -1.35 -0.60 -1.12 -0.28
9996 || orf19.5832 || HPT1 || || Putative hypoxanthine-guanine phosphoribosyltransferase; protein abundance affected by URA3 expression in the CAI4 strain background; protein level decreases in stationary phase; Spider biofilm induced || 1 -0.57 -0.76 -1.28 -1.34 -0.19 0.25 -0.80 -0.65 -1.20 0.03 0.45 0.28 -1.22 -0.45 -0.76 0.11
9997 || orf19.4808 || NUP188 || || Putative nuclear pore complex subunit; transcript regulated by Nrg1 and Mig1 || 1 -0.68 -0.60 -0.69 -0.59 -0.31 -0.32 -0.63 -0.24 -0.42 0.11 0.26 0.34 -0.43 -0.01 -0.51 -0.27
9998 || orf19.4705 || || || Ortholog(s) have tRNA adenylyltransferase activity, role in tRNA 3'-terminal CCA addition and cytosol, mitochondrial matrix localization || 1 -0.63 -0.87 -0.59 -1.08 -0.05 -0.24 -0.41 -0.18 -0.12 0.43 0.31 -0.01 -0.85 -0.15 -0.38 0.13
9999 || orf19.4705 || || || Ortholog(s) have tRNA adenylyltransferase activity, role in tRNA 3'-terminal CCA addition and cytosol, mitochondrial matrix localization || 1 -1.28 -0.90 -1.52 -1.34 -0.22 -0.35 -0.39 -0.14 -0.27 0.28 0.28 0.20 -1.56 -0.17 -0.52 0.38
10000 || orf19.1865 || MCS7 || || S. cerevisiae ortholog Mcs7 has a role in reciprocal meiotic recombination; Spider biofilm repressed || 1 -0.51 -0.38 -0.47 -0.51 -0.07 -0.02 -0.41 -0.06 -0.29 0.20 0.22 0.34 -0.43 -0.54 -0.14 0.28
10001 || orf19.3921 || || || Ortholog(s) have cell division site, cell tip, cytosol, nucleus localization || 1 -0.57 -0.61 -1.10 -1.12 -0.13 0.16 -0.51 -0.21 -0.66 -0.15 0.72 0.10 -0.87 -0.84 -0.46 0.37
10002 || orf19.3921 || || || Ortholog(s) have cell division site, cell tip, cytosol, nucleus localization || 1 -0.62 -0.60 -0.99 -1.05 -0.33 0.17 -0.55 -0.23 -0.74 -0.11 0.59 0.08 -1.02 -0.51 -0.44 0.84
10003 || orf19.3836 || || || Ortholog(s) have cytoplasm localization || 1 -0.80 -0.66 -1.39 -1.24 -0.20 0.09 0.07 0.02 -0.58 0.13 1.24 0.75 -0.78 -0.58 -0.67 0.55
10004 || orf19.5541 || || || Protein with similarity to S. pombe Nrd1p; transcription induced upon induction of hyphal growth; regulated by Cph1p, Efg1p, Cph2p; low-level expression; alkaline upregulated; fungal-specific (no human or murine homolog) || 1 -0.52 -0.46 -0.98 -0.78 -0.28 -0.47 -0.05 0.15 -1.10 0.18 0.42 0.62 -0.14 -0.28 0.12 0.34
10005 || orf19.1411 || || || Putative cytochrome P450; Hap43-repressed gene || 1 0.03 -0.56 -1.48 -0.74 -0.45 -0.07 -0.06 -0.18 -0.90 0.01 0.62 0.38 -0.10 -0.58 0.12 0.22
10006 || orf19.1993 || || || Ortholog(s) have structural molecule activity, role in proteasome assembly, ubiquitin-dependent protein catabolic process and nucleus, proteasome regulatory particle, lid subcomplex, proteasome storage granule localization || 1 -0.27 -0.21 -0.82 -0.57 -0.51 -0.44 -0.07 -0.38 -0.58 -0.00 0.40 0.16 -0.50 -0.50 0.46 0.45
10007 || orf19.6883 || || || Putative oxysterol binding protein family; probable peripheral membrane protein of the Golgi complex; flow model and Spider biofilm repressed || 1 -0.25 -0.22 -0.69 -0.61 -0.21 -0.28 -0.08 -0.09 -1.00 -0.12 0.35 -0.16 -0.35 -0.26 0.71 0.43
10008 || orf19.4769 || IPT1 || || Inositol phosphoryl transferase; catalyzes the synthesis of the most abundant sphingolipid, mannose-(inositol-P)2-ceramide, M(IP)2C, from MIPC; required for wild-type membrane localization of Cdr1; Spider biofilm induced || 1 -1.90 -2.16 -2.33 -2.46 -0.96 -0.53 -1.78 -1.23 -5.48 -0.95 1.09 1.42 -2.31 -1.89 1.58 1.23
10009 || orf19.851 || || || Protein of unknown function; repressed by Rim101; negatively modulates intracellular ATP levels during the development of azole resistance; induced by Ca(2+) in a calcineurin-dependent manner; Spider biofilm induced || 1 -0.79 -0.69 -0.47 -0.76 -0.40 -0.21 -0.45 -1.05 -1.28 -0.42 -0.02 0.67 -0.52 -0.28 0.76 0.25
10010 || orf19.3876 || ZCF19 || || Predicted Zn(II)2Cys6 transcription factor || 1 -1.48 -1.42 -1.25 -1.04 -0.36 -0.04 -0.52 -0.79 -2.31 -0.15 -0.45 1.17 -0.19 -0.66 1.06 0.54
10011 || orf19.7388 || PBS2 || || MAPK kinase (MAPKK); role in osmotic and oxidative stress responses, oxidative stress adaptation; required for stress regulation of Hog1p localization and activity; functional homolog of S. cerevisiae Pbs2p || 1 -0.70 -0.65 -0.99 -0.47 -0.25 0.19 -0.68 -0.62 -1.12 0.32 0.83 1.08 -0.23 -0.27 0.62 0.79
10012 || orf19.7388 || PBS2 || || MAPK kinase (MAPKK); role in osmotic and oxidative stress responses, oxidative stress adaptation; required for stress regulation of Hog1p localization and activity; functional homolog of S. cerevisiae Pbs2p || 1 -0.75 -0.69 -1.01 -0.58 -0.12 0.30 -0.65 -0.73 -1.20 0.51 0.93 1.08 -0.22 -0.05 0.94 0.95
10013 || orf19.1991 || || || Ortholog(s) have cytoplasm localization || 1 -0.34 -0.25 -0.57 -0.41 0.28 -0.00 -0.25 -0.28 -0.42 0.09 0.15 0.37 -0.19 0.22 0.14 0.36
10014 || orf19.878 || NBN1 || || Subunit of the NuA4 histone acetyltransferase complex; Plc1p-regulated || 1 -0.41 -0.69 -0.35 -0.34 0.21 -0.01 -0.38 -0.15 -0.58 -0.21 0.40 0.13 -0.46 -0.06 0.28 -0.04
10015 || orf19.881 || DFG16 || || Rim101 pathway protein that acts in Rim101 processing; regulates filamentation in response to alkaline pH; required for host tissue invasion during infection; flow model biofilm induced || 1 -0.02 -0.02 -0.49 -0.82 0.73 0.28 -0.34 -0.56 -0.10 -0.77 -0.10 -0.11 -0.31 -0.13 0.44 0.31
10016 || orf19.6225 || PCL7 || || Putative cyclin-like protein; possible Pho85 cyclin; hyphal repressed; induced by Mnl1 under weak acid stress || 1 0.15 0.19 -0.15 -0.73 0.83 0.70 -0.60 -0.56 -0.12 -1.25 0.12 -0.11 -0.15 -0.28 0.01 0.08
10017 || orf19.4309 || GRP2 || || Methylglyoxal reductase; regulation associated with azole resistance; induced in core stress response or by oxidative stress via Cap1, fluphenazine, benomyl, by Hap43 or with long term fluconazole treatment; Spider biofilm induced || 1 -0.87 -0.87 -0.90 -1.79 0.86 -0.64 -1.16 -0.52 -2.81 -0.31 0.32 -0.40 -0.76 0.31 -0.44
10018 || orf19.4309 || GRP2 || || Methylglyoxal reductase; regulation associated with azole resistance; induced in core stress response or by oxidative stress via Cap1, fluphenazine, benomyl, by Hap43 or with long term fluconazole treatment; Spider biofilm induced || 1 -0.52 -0.66 -0.52 -1.50 1.04 1.80 -0.54 -0.93 -0.69 -2.76 -0.17 0.23 -0.30 -1.00 0.22 -0.35
10019 || orf19.5742 || ALS9 || || ALS family cell-surface glycoprotein; expressed during infection of human epithelial cells; confers laminin adhesion to S. cerevisiae; highly variable; putative GPI-anchor; Hap43-repressed || 1 -0.22 -0.47 -0.81 -1.24 0.47 1.80 -0.60 -0.64 -1.08 -1.97 -0.35 -0.29 -0.21 -1.38 0.00 0.09
10020 || orf19.5742 || ALS9 || || ALS family cell-surface glycoprotein; expressed during infection of human epithelial cells; confers laminin adhesion to S. cerevisiae; highly variable; putative GPI-anchor; Hap43-repressed || 1 -0.41 -0.30 -1.28 -2.38 0.26 1.91 -0.97 -1.05 -1.08 -2.43 -0.46 -0.29 -0.19 -1.84 -0.38 -0.36
10021 || orf19.260 || SLD1 || || Sphingolipid delta-8 desaturase; catalyzes desaturation at C8 in the long-chain base moiety of ceramides in glucosylceramide synthesis, important for virulence; ketoconazole and hypoxia induced; Hap43-repressed; Spider biofilm induced || 1 -0.18 -0.42 -0.91 -1.35 0.20 0.29 -0.50 -0.80 -0.17 -1.40 -0.77 -0.50 -1.20 -1.49 -0.41 -0.38
10022 || orf19.6621 || MHP1 || || Protein similar to S. cerevisiae Mhp1p, which is involved in microtubule stabilization; transposon mutation affects filamentous growth; possibly transcriptionally regulated upon hyphal formation; possibly an essential gene (by UAU1 method) || 1 -0.29 -0.37 -0.30 -1.28 0.90 -0.06 -0.32 -0.60 -0.67 -1.46 -0.22 -0.86 -0.72 -0.89 0.09 -0.12
10023 || orf19.6121 || MNL1 || || Transcription factor; induces transcripts of stress response genes via SLE (STRE-like) elements; required for adaptation to weak acid stress; activates a subset of the genes that are repressed by Nrg1 || 1 -0.58 -0.60 -0.83 -0.79 0.61 0.28 -0.41 -0.50 -0.85 -1.24 -0.25 -0.90 -0.61 -0.84 0.53 -0.03
10024 || orf19.4045 || EST1 || || Telomerase subunit; allosteric activator of catalytic activity, but not required for catalytic activity; has TPR domain || 1 -0.83 -0.52 -0.49 -0.74 -0.05 0.06 0.03 -0.06 -0.08 -0.09 0.41 -0.08 -0.01 -0.05 0.07 -0.23
10025 || orf19.470 || || || Ortholog(s) have RNA polymerase II activating transcription factor binding, TBP-class protein binding, chromatin binding, protein complex scaffold activity || 1 -0.79 -0.81 -0.28 -0.95 -0.08 -0.07 -0.10 -0.20 -0.14 -0.34 0.45 0.27 0.10 -0.12 0.29 -0.07
10026 || orf19.4358 || || || Putative protein of unknown function; Hap43p-repressed gene; S. cerevisiae ortholog YDL157C localizes to mitochondria || 1 -1.09 -1.16 -1.39 -1.96 0.76 0.97 -0.15 -0.68 -0.63 -1.48 -0.01 -0.51 -0.25 -1.57 0.59 -0.16
10027 || orf19.974 || ROT2 || || Alpha-glucosidase II, catalytic subunit, required for N-linked protein glycosylation and normal cell wall synthesis; alkaline downregulated || 1 -0.66 -0.44 -0.64 -0.69 0.36 0.06 -0.18 -0.26 -0.04 -0.50 0.16 0.11 -0.11 -0.64 0.03 0.02
10028 || orf19.1381 || || || Ortholog of S. cerevisiae/S. pombe Lsb5; predicted role in actin cortical patch localization, actin filament organization, endocytosis; flow model biofilm induced; Spider biofilm repressed || 1 -0.56 -0.55 -0.81 -1.37 -0.22 -0.34 0.19 -0.23 -0.16 -1.48 0.29 -0.09 -0.09 -0.21 -0.33 0.75
10029 || orf19.1381 || || || Ortholog of S. cerevisiae/S. pombe Lsb5; predicted role in actin cortical patch localization, actin filament organization, endocytosis; flow model biofilm induced; Spider biofilm repressed || 1 -0.84 -0.80 -1.64 -1.96 -0.68 -0.51 -0.01 -0.44 -0.62 -1.87 0.17 -0.50 -0.31 -0.34 -0.39 0.52
10030 || orf19.411 || || || Protein similar to GTPase regulators; induced in low iron; transcript activated by Mnl1 under weak acid stress; Hap43-, Sfu1- and Sef1-regulated; flow model biofilm induced, Spider biofilm induced || 1 -1.13 -1.07 -2.07 -3.00 0.47 0.46 -1.09 -1.16 -1.63 -2.88 0.23 -0.70 -0.46 -0.43 -0.96 0.95
10031 || orf19.4212 || FET99 || || Multicopper oxidase family protein; similar to S. cerevisiae Fet3; does not complement S. cerevisiae fet3 mutant growth under low-iron; iron-repressed; regulated by Tup1, Rim101; flow model biofilm induced; Spider biofilm repressed || 1 -1.22 -1.25 -1.45 -1.63 -0.49 0.52 -0.72 -0.96 -1.73 -2.35 -0.02 0.52 0.68 -0.33 -0.13 0.82
10032 || orf19.2972 || PDE2 || || High affinity cyclic nucleotide phosphodiesterase; moderates signaling by cAMP; required for virulence, switching, cell wall, hyphal, not pseudohyphal growth; expressed shortly after hyphal induction; rat catheter and Spider biofilm induced || 1 -0.73 -0.74 -0.94 -1.21 -0.23 0.30 -0.06 -1.31 -0.66 -1.54 -0.13 0.04 0.09 0.20 0.01 0.48
10033 || orf19.941 || SEC14 || || Essential protein; functional homolog of S. cerevisiae Sec14p, a Golgi phosphatidylinositol/phosphatidylcholine transfer protein that regulates choline-phosphate cytidyltransferase and thereby affects secretion; biofilm-regulated || 1 -0.62 -0.67 -1.01 -0.66 0.35 0.53 -0.25 -0.53 -1.06 -0.69 0.17 -0.26 -0.26 -0.14 0.08 -0.05
10034 || orf19.941 || SEC14 || || Essential protein; functional homolog of S. cerevisiae Sec14p, a Golgi phosphatidylinositol/phosphatidylcholine transfer protein that regulates choline-phosphate cytidyltransferase and thereby affects secretion; biofilm-regulated || 1 -0.71 -0.74 -1.21 -0.83 0.33 0.58 -0.41 -0.54 -1.18 -0.64 0.05 -0.41 -0.27 -0.35 -0.03 -0.10
10035 || orf19.527 || || || Protein of unknown function; flow model biofilm induced || 1 -0.34 -0.80 -0.62 -0.89 0.04 0.09 -0.42 -0.60 -1.01 -0.41 0.00 -0.45 -0.22 -0.62 -0.21 -0.34
10036 || orf19.7177 || KAP120 || || Putative karyopherin; mutation confers hypersensitivity to cytochalasin D || 1 -0.85 -0.77 -1.47 -1.02 0.11 0.08 -0.58 -0.82 -0.55 -0.56 -0.34 -0.28 -0.59 -0.34 -0.08 -0.43
10037 || orf19.6861 || || || Ortholog(s) have ubiquitin-protein ligase activity and role in anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process, chromatin assembly, protein ubiquitination || 1 -0.65 -0.58 -1.23 -1.32 0.15 -0.08 -0.49 -1.00 -0.98 -0.64 -0.32 0.03 0.18 -0.34 0.08 0.02
10038 || orf19.6968 || || || Protein of unknown function; Hog1-repressed; Spider biofilm induced || 1 -1.12 -1.18 -1.93 -1.62 0.03 0.10 -0.26 -1.27 -0.99 -0.71 -0.71 -0.37 0.40 -0.68 -0.29 -0.66
10039 || orf19.6968 || || || Protein of unknown function; Hog1-repressed; Spider biofilm induced || 1 -1.13 -1.26 -1.40 -1.57 -0.03 0.13 -0.05 -0.65 -0.58 -0.47 -0.23 -0.01 0.64 -0.45 0.06 -0.25
10040 || orf19.5101 || CCR4 || || Component of the Ccr4-Pop2 mRNA deadenylase; transposon mutation affects filamentous growth || 1 -0.33 -0.54 -0.59 -0.61 -0.12 -0.33 -0.14 -0.19 -0.23 -0.40 0.17 0.15 -0.27 -0.48 0.22 0.13
10041 || orf19.4686 || || || Ortholog of S. cerevisiae : ESL1, C. dubliniensis CD36 : Cd36_41030, C. parapsilosis CDC317 : CPAR2_401340, Candida tenuis NRRL Y-1498 : CANTEDRAFT_104645 and Debaryomyces hansenii CBS767 : DEHA2E18766g || 1 -0.20 -0.35 -1.01 -1.09 -0.10 -0.49 0.26 -0.20 -0.25 -0.54 0.14 0.31 -0.24 0.12 0.14 0.73
10042 || orf19.1460 || || || Putative glutamine-dependent NAD synthetase, involved in NAD salvage pathway || 1 -0.43 -0.65 -1.08 -0.96 0.13 -0.29 0.12 -0.04 -0.33 -0.16 0.12 -0.04 -0.35 0.17 0.22 0.51
10043 || orf19.5892 || || || Ortholog of S. cerevisiae Hul4; similar to hect domain E3 ubiquitin-protein ligases; Hap43-repressed gene || 1 -0.64 -0.75 -1.19 -1.05 0.04 -0.29 0.39 0.13 -0.29 -0.65 0.36 -0.16 -0.32 0.12 0.23 0.57
10044 || orf19.835 || || || Ortholog(s) have role in nucleosome mobilization and Ino80 complex, cytosol localization || 1 -0.47 -0.43 -1.41 -1.45 -0.11 -0.39 0.02 -0.05 -0.04 -0.50 0.60 -0.07 0.02 0.02 0.32 0.40
10045 || orf19.2835 || || || Ortholog(s) have SUMO activating enzyme activity, role in cellular response to DNA damage stimulus, protein sumoylation, regulation of mitotic cell cycle and SUMO activating enzyme complex, cytosol localization || 1 -0.39 -0.54 -1.06 -1.26 -0.31 -0.33 0.24 -0.00 -0.46 -0.39 0.30 -0.15 0.01 -0.12 -0.21 0.37
10046 || orf19.2044 || PGA27 || || Putative GPI-anchored protein || 1 -0.47 -1.07 -1.36 -1.89 -0.25 -0.33 -0.60 -0.23 -1.23 -0.94 0.48 -0.21 -0.15 -0.57 0.14 0.60
10047 || orf19.1460 || || || Putative glutamine-dependent NAD synthetase, involved in NAD salvage pathway || 1 -0.25 -0.40 -0.84 -0.88 0.09 -0.12 -0.29 -0.10 -0.36 -0.41 -0.01 -0.05 -0.16 0.00 0.05 0.47
10048 || orf19.2671 || || || Protein with a predicted FAD-dependent pyridine nucleotide reductase domains; putative oxidoreductase; Plc1-regulated; possibly an essential gene, disruptants not obtained by UAU1 method || 1 -1.64 -1.57 -1.99 -3.42 -0.35 -0.69 -0.69 -0.48 -1.62 -1.85 0.94 0.53 -0.00 0.52 0.58 1.72
10049 || orf19.3362 || || || Has domain(s) with predicted flavin adenine dinucleotide binding, oxidoreductase activity and role in oxidation-reduction process || 1 -1.56 -2.09 -3.86 -3.67 -0.32 -1.03 -0.77 -0.52 -1.79 -2.23 1.16 0.65 0.02 1.16 0.78 1.84
10050 || orf19.2671 || || || Protein with a predicted FAD-dependent pyridine nucleotide reductase domains; putative oxidoreductase; Plc1-regulated; possibly an essential gene, disruptants not obtained by UAU1 method || 1 -1.77 -1.73 -2.74 -2.74 -0.54 -1.22 -0.99 -1.26 -2.55 -2.54 0.74 -0.15 0.21 0.52 0.20 1.12
10051 || orf19.2640 || FUR1 || || Uracil phosphoribosyltransferase; predicted tetrameric enzyme of pyrimidine salvage; mutations associated with flucytosine resistance in clade I clinical isolates; flucytosine, macrophage-induced protein; levels decrease in stationary phase || 1 -0.78 -0.77 -1.64 -1.75 0.24 -0.28 -0.05 -0.16 -0.80 -0.64 0.71 -0.08 -0.61 -0.56 -0.32 0.05
10052 || orf19.7326 || || || Ortholog(s) have protein-lysine N-methyltransferase activity, role in peptidyl-lysine dimethylation and cytoplasm, nucleus localization || 1 -0.15 -0.32 -0.88 -1.08 -0.04 -0.11 -0.18 -0.04 -0.34 -0.43 -0.01 -0.30 -0.24 -0.45 0.18 0.27
10053 || orf19.2084 || CDH1 || || Protein involved in regulation of mitosis; similar to S. cerevisiae Cdh1, which is an APC/C component; transcriptionally induced by Mnl1 under weak acid stress || 1 -0.40 -0.41 -0.64 -0.82 0.19 -0.27 -0.17 -0.14 -0.45 -0.55 -0.25 -0.30 -0.25 -0.08 0.27 0.03
10054 || orf19.6425 || SKI2 || || Ortholog(s) have role in cellular response to cadmium ion, detoxification of cadmium ion, nuclear-transcribed mRNA catabolic process, 3'-5' exonucleolytic nonsense-mediated decay, nuclear-transcribed mRNA catabolic process, non-stop decay || 1 -0.43 -0.50 -0.91 -1.31 0.14 -0.29 -0.21 -0.22 -0.57 -0.48 -0.13 -0.19 -0.64 -0.23 0.01 -0.08
10055 || orf19.2095 || || || Ortholog(s) have role in negative regulation of transcription from RNA polymerase II promoter in response to iron and cytosol, nucleus localization || 1 -0.72 -0.75 -1.38 -1.94 0.11 -0.37 -0.67 -0.71 -1.00 -0.81 -0.05 -0.37 -1.03 -0.96 0.22 -0.30
10056 || orf19.4003 || TIP20 || || Protein interacting with Sec20p, possibly involved in retrograde transport between the Golgi and the endoplasmic reticulum; similar to S. cerevisiae Tip20p || 1 -0.48 -0.63 -0.94 -0.82 0.13 -0.37 -0.52 -0.39 -0.67 -0.60 0.13 -0.26 -0.62 -0.44 0.22 -0.05
10057 || orf19.6874 || || || Putative helix-loop-helix (HLH) transcription factor with a role in filamentous growth || 1 -1.89 -2.15 -1.82 -1.66 0.19 0.81 -0.85 -1.52 -1.61 -1.23 -0.14 -0.55 -1.00 -1.04 -0.09 0.28
10058 || orf19.4737 || TPO3 || || Putative polyamine transporter; MFS-MDR family; induced by Sfu1, regulated upon white-opaque; decreased expression in hyphae vs yeast-form cells; regulated by Nrg1; Spider biofilm repressed || 1 -3.80 -3.66 -3.69 -4.20 0.39 1.02 -1.07 -2.01 -2.54 -1.75 0.64 -0.41 -1.53 -0.66 -0.90 0.71
10059 || orf19.4737 || TPO3 || || Putative polyamine transporter; MFS-MDR family; induced by Sfu1, regulated upon white-opaque; decreased expression in hyphae vs yeast-form cells; regulated by Nrg1; Spider biofilm repressed || 1 -2.89 -2.84 -3.01 -3.81 0.58 0.80 -1.01 -1.87 -2.31 -1.84 0.55 -0.49 -1.28 -0.71 -0.98 0.87
10060 || orf19.4737 || TPO3 || || Putative polyamine transporter; MFS-MDR family; induced by Sfu1, regulated upon white-opaque; decreased expression in hyphae vs yeast-form cells; regulated by Nrg1; Spider biofilm repressed || 1 -1.81 -1.97 -2.22 -2.78 0.57 1.12 -0.58 -1.34 -1.81 -1.35 1.09 -0.05 -1.08 -0.48 -0.44 1.06
10061 || orf19.4737 || TPO3 || || Putative polyamine transporter; MFS-MDR family; induced by Sfu1, regulated upon white-opaque; decreased expression in hyphae vs yeast-form cells; regulated by Nrg1; Spider biofilm repressed || 1 -2.19 -2.29 -2.23 -2.86 0.74 1.20 -0.67 -1.52 -1.85 -1.42 0.97 0.03 -1.01 -0.15 -0.52 0.91
10062 || orf19.4737 || TPO3 || || Putative polyamine transporter; MFS-MDR family; induced by Sfu1, regulated upon white-opaque; decreased expression in hyphae vs yeast-form cells; regulated by Nrg1; Spider biofilm repressed || 1 -2.41 -2.62 -2.17 -2.16 0.46 1.18 -0.98 -1.63 -1.78 -1.43 0.69 -0.07 -1.39 -0.23 -0.71 0.90
10063 || orf19.1229 || || || Ortholog(s) have importin-alpha export receptor activity, role in cell division, protein export from nucleus and nuclear membrane localization || 1 -0.85 -0.84 -1.24 -1.37 0.48 0.37 0.08 -0.30 -0.34 -0.51 0.13 0.08 0.20 -0.38 0.16 0.24
10064 || orf19.951 || || || Protein of unknown function; transcript repressed upon yeast-hyphal switch; fluconazole-induced; Hap43-repressed; flow model biofilm induced || 1 -1.79 -1.63 -2.46 -3.74 1.27 0.89 -0.32 -0.82 -0.77 -2.13 0.17 -0.85 -0.10 -0.80 0.49 0.86
10065 || orf19.2048 || || || Proten of unknown function; transcript positively regulated by Sfu1; Hap43 repressed; Spider biofilm induced || 1 -3.08 -2.70 -3.49 -4.27 0.85 1.48 -0.07 -0.18 -2.21 -4.09 -0.05 -1.47 -1.94 -1.71 0.58 0.86
10066 || orf19.2048 || || || Proten of unknown function; transcript positively regulated by Sfu1; Hap43 repressed; Spider biofilm induced || 1 -2.59 -2.00 -2.92 -3.31 1.50 2.23 0.33 0.34 -1.41 -3.39 0.43 -0.84 -1.48 -0.97 0.73 1.21
10067 || orf19.508 || QDR1 || || Putative antibiotic resistance transporter; regulated by white-opaque switch, Nrg1, Tup1; Hap43, caspofungin repressed; repressed during chlamydospore formation; flow model biofilm induced; Spider biofilm repressed || 1 -1.79 -1.62 -1.89 -3.36 0.97 1.46 -0.08 0.15 -0.61 -3.17 0.63 -0.34 -0.55 -0.51 -0.46 0.98
10068 || orf19.508 || QDR1 || || Putative antibiotic resistance transporter; regulated by white-opaque switch, Nrg1, Tup1; Hap43, caspofungin repressed; repressed during chlamydospore formation; flow model biofilm induced; Spider biofilm repressed || 1 -1.69 -1.76 -1.47 -2.76 0.61 1.58 -0.40 -0.55 -0.95 -3.14 0.18 -0.24 -0.75 -0.84 -0.72 0.73
10069 || orf19.508 || QDR1 || || Putative antibiotic resistance transporter; regulated by white-opaque switch, Nrg1, Tup1; Hap43, caspofungin repressed; repressed during chlamydospore formation; flow model biofilm induced; Spider biofilm repressed || 1 -3.09 -2.94 -3.02 -4.71 0.47 1.29 -0.60 -0.50 -0.99 -3.73 0.12 -0.36 -1.13 -0.62 -0.92 0.69
10070 || orf19.508 || QDR1 || || Putative antibiotic resistance transporter; regulated by white-opaque switch, Nrg1, Tup1; Hap43, caspofungin repressed; repressed during chlamydospore formation; flow model biofilm induced; Spider biofilm repressed || 1 -2.86 -2.94 -2.76 -4.93 0.47 1.35 -0.43 -0.25 -0.76 -3.47 0.43 -0.15 -1.27 -0.71 -0.68 0.67
10071 || orf19.508 || QDR1 || || Putative antibiotic resistance transporter; regulated by white-opaque switch, Nrg1, Tup1; Hap43, caspofungin repressed; repressed during chlamydospore formation; flow model biofilm induced; Spider biofilm repressed || 1 -3.23 -3.14 -2.81 -5.35 0.56 1.35 -0.37 -0.07 -0.56 -3.43 0.21 -0.32 -0.95 -0.31 -1.04 0.48
10072 || orf19.1868 || RNR22 || || Putative ribonucleoside diphosphate reductase;colony morphology-related gene regulation by Ssn6; transcript regulated by tyrosol and cell density; Hap43-repressed; Spider biofilm induced || 1 -1.70 -1.64 -2.26 -3.71 -0.09 0.88 0.40 -0.56 -0.10 -3.10 -0.02 0.12 -0.68 -0.60 -0.81 0.99
10073 || orf19.6816 || || || Putative xylose and arabinose reductase; flow model biofilm induced; Spider biofilm repressed || 1 -0.91 -1.04 -2.07 -3.01 0.55 0.44 -0.76 -0.70 -0.97 -2.39 0.45 -0.02 -0.59 -1.42 0.20 0.14
10074 || orf19.6816 || || || Putative xylose and arabinose reductase; flow model biofilm induced; Spider biofilm repressed || 1 -0.81 -0.82 -1.69 -2.72 0.82 0.99 -0.44 -0.44 -0.44 -1.94 0.77 0.60 -0.57 -0.83 0.46 0.73
10075 || orf19.7529 || EPL1 || || Subunit of the NuA4 histone acetyltransferase complex || 1 -0.38 -0.43 -0.42 -0.76 0.41 0.33 -0.27 -0.15 -0.08 -0.55 0.13 0.10 -0.22 -0.16 0.29 0.42
10076 || orf19.6684 || PNC1 || || Putative nicotinamidase, involved in NAD salvage pathway; decreased transcription is observed in an azole-resistant strain that overexpresses MDR1 || 1 -1.19 -1.26 -1.53 -2.13 0.77 1.06 -0.87 -0.75 -0.32 -0.71 0.32 0.65 -0.55 -0.03 0.36 0.94
10077 || orf19.6684 || PNC1 || || Putative nicotinamidase, involved in NAD salvage pathway; decreased transcription is observed in an azole-resistant strain that overexpresses MDR1 || 1 -0.33 -0.59 -0.94 -1.61 0.66 0.89 -0.73 -0.59 -0.45 -0.61 0.33 0.53 -0.37 -0.19 0.42 0.80
10078 || orf19.4824 || || || Planktonic growth-induced gene || 1 -0.67 -0.72 -1.07 -1.50 0.46 0.89 -0.69 -0.50 -0.50 -1.45 0.12 0.85 -0.42 -0.00 0.20 0.74
10079 || orf19.349 || || || Ortholog(s) have role in aerobic respiration, mRNA metabolic process and mitochondrial outer membrane localization || 1 -0.92 -1.12 -1.56 -1.90 0.71 0.56 -0.41 -0.80 -0.65 -1.09 0.54 0.63 -0.89 -0.12 0.31 0.62
10080 || orf19.277 || THI6 || || Putative thiamin-phosphate pyrophosphorylase, hydroxyethylthiazole kinase; fungal-specific; Spider biofilm induced || 1 -1.86 -2.07 -1.99 -2.06 0.38 0.55 -0.74 -1.48 -0.43 -1.60 0.74 0.67 -1.20 -0.32 0.68 0.95
10081 || orf19.5079 || CDR4 || || Putative ABC transporter superfamily; fluconazole, Sfu1, Hog1, core stress response induced; caspofungin repressed; fluconazole resistance not affected by mutation or correlated with expression; rat catheter and flow model biofilm induced || 1 -3.93 -3.92 -2.80 -4.98 0.69 1.66 -1.93 -2.34 -2.09 -4.25 -0.60 0.10 -1.37 -1.22 1.19 0.07
10082 || orf19.2838 || || || Protein of unknown function; mutation confers hypersensitivity to amphotericin B; flow model biofilm induced || 1 -2.20 -2.11 -1.88 -2.32 0.15 0.95 -1.28 -1.54 -0.81 -1.56 -0.54 0.25 -0.69 -0.83 0.41 0.34
10083 || orf19.2838 || || || Protein of unknown function; mutation confers hypersensitivity to amphotericin B; flow model biofilm induced || 1 -1.99 -1.67 -1.24 -1.75 0.47 1.13 -1.10 -1.31 -0.24 -1.69 -0.50 0.47 -0.64 -0.78 0.56 0.70
10084 || orf19.7235 || || || Putative protein of unknown function; mutation confers hypersensitivity to amphotericin B || 1 -1.18 -1.11 -0.92 -1.47 0.82 0.74 -0.61 -0.75 -0.42 -1.05 0.31 0.25 -0.43 -0.32 0.78 0.61
10085 || orf19.5079 || CDR4 || || Putative ABC transporter superfamily; fluconazole, Sfu1, Hog1, core stress response induced; caspofungin repressed; fluconazole resistance not affected by mutation or correlated with expression; rat catheter and flow model biofilm induced || 1 -2.73 -2.73 -2.13 -4.34 1.67 2.19 -1.10 -1.38 -1.43 -3.69 0.32 0.49 -0.52 -0.76 1.82 0.67
10086 || orf19.5911 || CMK1 || || Putative calcium/calmodulin-dependent protein kinase II; expression regulated upon white-opaque switching; biochemically purified Ca2+/CaM-dependent kinase is soluble, cytosolic, monomeric, and serine-autophosphorylated; Hap43p-repressed || 1 -1.72 -1.68 -2.62 -3.58 1.15 1.43 -1.54 -1.20 -1.90 -2.77 1.04 0.13 -0.50 -1.55 1.11 1.09
10087 || orf19.5911 || CMK1 || || Putative calcium/calmodulin-dependent protein kinase II; expression regulated upon white-opaque switching; biochemically purified Ca2+/CaM-dependent kinase is soluble, cytosolic, monomeric, and serine-autophosphorylated; Hap43p-repressed || 1 -3.56 -3.62 -3.62 -4.82 1.33 1.43 -2.01 -1.07 -1.63 -2.76 1.20 0.19 -0.46 -1.37 1.15 0.85
10088 || orf19.5911 || CMK1 || || Putative calcium/calmodulin-dependent protein kinase II; expression regulated upon white-opaque switching; biochemically purified Ca2+/CaM-dependent kinase is soluble, cytosolic, monomeric, and serine-autophosphorylated; Hap43p-repressed || 1 -4.08 -4.01 -4.07 -4.98 1.17 1.52 -2.24 -1.47 -2.07 -2.89 0.93 0.35 -0.94 -1.29 1.21 1.10
10089 || orf19.5911 || CMK1 || || Putative calcium/calmodulin-dependent protein kinase II; expression regulated upon white-opaque switching; biochemically purified Ca2+/CaM-dependent kinase is soluble, cytosolic, monomeric, and serine-autophosphorylated; Hap43p-repressed || 1 -3.63 -3.37 -3.54 -4.65 1.04 1.42 -2.25 -1.67 -2.19 -3.05 1.05 0.14 -0.87 -1.39 1.03 1.18
10090 || orf19.4857 || || || Protein with a dual-specificity phosphatase domain; Hap43-induced gene || 1 -1.03 -1.11 -1.07 -1.68 0.59 0.63 -0.73 -0.27 -0.53 -1.15 0.37 0.08 -0.63 -0.54 -0.06 0.48
10091 || orf19.4824 || || || Planktonic growth-induced gene || 1 -1.41 -1.45 -1.82 -2.52 0.89 0.97 -0.88 -0.52 -0.64 -1.82 0.53 0.55 -1.15 -0.89 0.22 0.60
10092 || orf19.5911 || CMK1 || || Putative calcium/calmodulin-dependent protein kinase II; expression regulated upon white-opaque switching; biochemically purified Ca2+/CaM-dependent kinase is soluble, cytosolic, monomeric, and serine-autophosphorylated; Hap43p-repressed || 1 -1.66 -2.73 -1.96 -2.37 0.92 1.36 -1.79 -1.33 -1.89 -2.73 0.71 0.07 -0.79 -1.44 0.70 0.86
10093 || orf19.2047 || || || Putative protein of unknown function; Hap43p-repressed gene; mutation confers hypersensitivity to toxic ergosterol analog, and to amphotericin B || 1 -1.32 -1.28 -1.18 -1.68 0.92 1.22 -1.09 -0.89 -0.68 -1.80 0.12 -0.09 -1.04 -0.93 0.28 0.27
10094 || orf19.583 || || || Indoleamine 2,3-dioxygenase (IDO); rate-limiting enzyme of tryptophan catabolism via kynurenine; enzyme inhibition by 1-methyl-D,L-tryptophan increases hyphal growth; expressed in yeast and hyphae; rat catheter and Spider biofilm induced || 1 -0.48 -0.45 -0.72 -1.20 0.27 0.61 -0.07 -0.32 -0.24 -0.84 -0.04 -0.23 -0.44 -0.12 0.42 0.32
10095 || orf19.4777 || DAK2 || || Putative dihydroxyacetone kinase; repressed by yeast-hypha switch; fluconazole-induced; caspofungin repressed; protein enriched in stationary phase yeast cultures; flow model biofilm induced; rat catheter and Spider biofilm repressed || 1 -1.92 -1.89 -2.21 -3.82 0.26 0.46 -0.33 -0.50 -0.08 -1.62 0.47 0.22 -1.83 -0.97 -0.05 0.61
10096 || orf19.4823 || LIP6 || || Secreted lipase, member of family of lipase genes expressed differentially in response to carbon source and during infection; may have a role in nutrition and/or in creating an acidic microenvironment; induced on adherence to polystyrene || 1 -0.80 -0.86 -0.94 -1.41 0.02 0.28 -0.61 -0.43 -0.29 -0.85 -0.08 0.14 -0.89 -0.53 -0.54 0.46
10097 || orf19.1229 || || || Ortholog(s) have importin-alpha export receptor activity, role in cell division, protein export from nucleus and nuclear membrane localization || 1 -0.61 -1.18 -1.46 -1.49 -0.31 0.03 -0.32 -0.44 -0.41 -0.44 -0.05 -0.12 -0.22 -0.43 -0.40 0.01
10098 || orf19.5525 || || || Putative oxidoreductase; protein levels affected by URA3 expression in CAI-4 strain background; Efg1, Efh1 regulated; Rgt1-repressed; protein present in exponential and stationary growth phase yeast; rat catheter biofilm repressed || 1 -1.47 -1.59 -1.19 -1.32 -0.02 0.07 -0.10 -0.27 -0.77 -1.11 0.40 -0.23 -0.55 -0.87 0.37 0.06
10099 || orf19.5674 || PGA10 || || GPI anchored membrane protein; utilization of hemin and hemoglobin for Fe in host; Rim101 at ph8/hypoxia/ketoconazole/ciclopirox/hypha-induced; required for RPMI biofilm formation, Bcr1-induced in a/a biofilm; rat catheter biofilm repressed || 1 -3.01 -3.97 -4.23 -3.53 -2.05 -1.16 -1.66 -2.13 -1.75 -3.85 0.89 0.17 -1.57 -2.10 0.19 1.34
10100 || orf19.1190 || STV1 || || Predicted subunit a of vacuolar proton-translocating ATPase V0 domain, Golgi isoform || 1 -0.65 -0.67 -0.81 -0.86 -0.16 -0.10 -0.37 -0.42 -0.29 -0.92 0.06 0.14 -0.55 -0.36 0.04 0.40
10101 || orf19.5729 || FGR17 || || Putative DNA-binding transcription factor; has zinc cluster DNA-binding motif; lacks an ortholog in S. cerevisiae; transposon mutation affects filamentous growth; Hap43p-repressed gene || 1 -1.84 -1.88 -2.59 -3.02 -0.37 0.35 -0.95 -1.15 -0.92 -2.97 -0.14 0.05 -0.76 -1.19 0.09 1.03
10102 || orf19.5729 || FGR17 || || Putative DNA-binding transcription factor; has zinc cluster DNA-binding motif; lacks an ortholog in S. cerevisiae; transposon mutation affects filamentous growth; Hap43p-repressed gene || 1 -1.87 -2.04 -1.88 -2.48 -0.61 0.09 -0.88 -1.16 -0.94 -2.47 -0.40 -0.22 -0.94 -0.83 -0.29 0.85
10103 || orf19.5729 || FGR17 || || Putative DNA-binding transcription factor; has zinc cluster DNA-binding motif; lacks an ortholog in S. cerevisiae; transposon mutation affects filamentous growth; Hap43p-repressed gene || 1 -2.20 -2.32 -2.07 -2.13 -0.62 0.23 -0.89 -1.29 -1.20 -2.27 0.01 -0.17 -0.50 -0.98 0.00 0.37
10104 || orf19.592 || || || Ortholog of S. cerevisiae YNL092W and S. pombe SPBC1778.07; a putative N2227-like methyltransferase; Hap43-repressed gene || 1 -1.23 -1.41 -1.05 -1.29 0.06 0.00 -0.24 -0.40 -0.36 -0.63 0.04 -0.12 -0.30 -0.12 0.16 -0.24
10105 || orf19.2116 || NAT2 || || Putative N-terminal acetyltransferase; Hap43p-repressed gene; mutation confers hypersensitivity to toxic ergosterol analog || 1 -1.56 -1.78 -1.69 -1.69 0.25 0.27 -0.48 -0.52 -0.22 -0.36 0.40 0.50 -1.10 -0.69 0.16 0.17
10106 || orf19.6396 || || || Putative patatin-like phospholipase; similar to S. cerevisiae Nte1p, which is predicted to be a membrane protein; antigenic during human oral infection; Hap43p-repressed gene || 1 -1.91 -2.14 -2.15 -1.81 -0.16 -0.14 -0.73 -0.58 -0.68 -0.68 0.64 0.51 -1.01 -0.44 0.37 0.45
10107 || orf19.3663.1 || || || Predicted plasma membrane protein; gene has intron || 1 -2.12 -2.11 -2.20 -1.77 -0.10 0.01 -1.03 -0.80 -0.75 -1.01 0.25 0.65 -1.35 -0.71 0.19 -0.18
10108 || orf19.1691 || || || Plasma-membrane-localized protein; filament induced; Hog1, ketoconazole, fluconazole and hypoxia-induced; regulated by Nrg1, Tup1, Upc2; induced by prostaglandins; flow model biofilm induced; rat catheter and Spider biofilm repressed || 1 -6.80 -6.83 -6.26 -7.70 0.98 0.94 -2.75 -2.11 -2.09 -4.38 -4.24 -4.21 -0.43 0.23
10109 || orf19.6396 || || || Putative patatin-like phospholipase; similar to S. cerevisiae Nte1p, which is predicted to be a membrane protein; antigenic during human oral infection; Hap43p-repressed gene || 1 -2.09 -1.77 -2.14 -1.69 -0.27 -0.31 -0.86 -0.81 -0.85 -0.89 0.22 0.20 -0.91 -0.86 0.09 0.79
10110 || orf19.7565 || GNP3 || || Putative high-affinity glutamine permease; fungal-specific (no human or murine homolog) || 1 -2.06 -2.23 -1.90 -1.58 -0.47 -0.05 -1.43 -1.25 -0.93 -0.75 -0.23 0.45 -1.27 -0.73 -0.07 0.30
10111 || orf19.301 || PGA18 || || Putative GPI-anchored protein; regulated by Nrg1, Tup1; rat catheter biofilm repressed || 1 -2.54 -2.45 -2.02 -1.85 -0.44 -0.15 -1.30 -1.12 -0.73 -0.77 -0.08 0.08 -0.87 -0.81 -0.24 0.39
10112 || orf19.301 || PGA18 || || Putative GPI-anchored protein; regulated by Nrg1, Tup1; rat catheter biofilm repressed || 1 -2.03 -2.22 -2.55 -1.19 -0.23 -0.04 -1.09 -1.13 -0.91 -0.87 -0.10 0.16 -0.73 -0.76 -0.18 0.08
10113 || orf19.4912 || || || Ortholog(s) have ubiquitin protein ligase binding activity, role in protein ubiquitination, ubiquitin-dependent endocytosis and Golgi apparatus, clathrin-coated vesicle, cytosol, nucleus, plasma membrane localization || 1 -1.51 -1.84 -1.85 -2.68 -0.50 -0.46 -1.00 -0.85 -0.87 -0.90 -0.28 -0.11 -0.27 -0.89 0.04 0.38
10114 || orf19.5034 || YBP1 || || Protein involved in response to oxidative stress, binds and stabilizes Cap1p transcription factor in response to H2O2; essential for macrophage killing || 1 -1.40 -1.26 -1.56 -1.59 -0.25 -0.37 -0.30 -0.70 -0.38 -0.43 -0.29 0.15 -0.85 -0.72 -0.07 -0.13
10115 || orf19.4006 || || || Ortholog(s) have cytosol, nucleus localization || 1 -1.48 -1.43 -1.80 -2.22 -0.56 -0.72 -0.51 -0.88 -0.56 -0.55 -0.09 0.05 -1.05 -0.87 0.23 0.20
10116 || orf19.1193 || GNP1 || || Similar to asparagine and glutamine permease; fluconazole, caspofungin induced; regulated by Nrg1, Mig1, Tup1, Gcn2, Gcn4, and alkaline regulated by Rim101; repressed during chlamydospore formation; rat catheter, flow model biofilm induced || 1 -1.76 -1.56 -2.43 -2.61 -0.88 -0.79 -0.32 -0.84 -0.33 -0.97 -0.27 -0.16 -1.20 -0.93 0.09 0.25
10117 || orf19.1193 || GNP1 || || Similar to asparagine and glutamine permease; fluconazole, caspofungin induced; regulated by Nrg1, Mig1, Tup1, Gcn2, Gcn4, and alkaline regulated by Rim101; repressed during chlamydospore formation; rat catheter, flow model biofilm induced || 1 -1.66 -1.63 -2.26 -2.76 -0.75 -0.50 -0.26 -0.80 0.00 -0.64 -0.08 0.37 -0.99 -0.67 0.33 0.40
10118 || orf19.880 || || || Ortholog(s) have role in cargo loading into COPII-coated vesicle and COPII vesicle coat, cytosol, mating projection tip localization || 1 -1.28 -1.24 -1.66 -1.83 -0.35 -0.32 -0.43 -0.56 -0.39 0.05 -0.14 0.12 -0.47 -0.09 0.22 0.15
10119 || orf19.3059 || SUA71 || || Transcription factor TFIIB; required for transcription initiation and start site selection by RNA polymerase II; downregulated during planktonic growth, whereas related SUA72 is induced; induced by Tbf1; rat catheter, Spider biofilm induced || 1 -1.43 -1.41 -1.60 -1.92 -0.22 -0.29 -0.06 -0.50 -0.66 -0.66 0.05 0.06 0.05 -0.79 0.43 0.38
10120 || orf19.3059 || SUA71 || || Transcription factor TFIIB; required for transcription initiation and start site selection by RNA polymerase II; downregulated during planktonic growth, whereas related SUA72 is induced; induced by Tbf1; rat catheter, Spider biofilm induced || 1 -1.28 -1.48 -1.74 -1.86 -0.43 -0.50 0.05 -0.45 -0.50 -0.56 0.21 0.00 -0.38 -0.31 0.40 0.34
10121 || orf19.4540 || UBC8 || || Predicted ubiquitin-conjugating enzyme that negatively regulates gluconeogenesis by mediating the glucose-induced ubiquitination of fructose-1,6-bisphosphatase; induced by alpha pheromone in SpiderM medium || 1 -1.99 -2.17 -2.00 -1.96 -0.72 -0.54 -0.36 -0.53 -0.19 -0.66 -0.13 0.24 -0.56 -0.29 0.79 0.68
10122 || orf19.5459 || || || mRNA polyadenylation regulating protein; Hap43-repressed; transcript is upregulated in RHE model of oral candidiasis and in clinical isolates from HIV+ patients with oral candidiasis; Spider biofilm repressed || 1 -0.79 -0.71 -0.66 -0.61 -0.10 -0.18 -0.07 -0.09 -0.23 -0.24 0.12 0.07 -0.19 -0.11 0.44 0.27
10123 || orf19.6393 || || || Putative Arf3p GTPase activating protein; Hap43p-repressed gene; possibly an essential gene, disruptants not obtained by UAU1 method || 1 -1.07 -1.08 -1.50 -1.48 0.31 -0.17 -0.18 -0.23 -0.49 -0.72 0.09 -0.25 -0.17 -0.32 0.41 0.52
10124 || orf19.4263 || || || Has domain(s) with predicted nucleotide binding activity || 1 -0.99 -1.33 -1.14 -1.08 -0.19 -0.40 -0.36 -0.34 -0.54 -0.75 0.19 -0.19 -0.22 0.14 0.51 0.51
10125 || orf19.4262 || || || Ortholog(s) have mRNA binding activity and role in cellular protein complex localization, establishment of mitochondrion localization, nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay || 1 -0.98 -0.96 -1.33 -1.33 -0.12 -0.47 -0.44 -0.48 -0.70 -0.59 -0.10 0.04 -0.15 0.12 0.06 0.93
10126 || orf19.4263 || || || Has domain(s) with predicted nucleotide binding activity || 1 -0.99 -0.87 -0.99 -1.04 -0.21 -0.35 -0.31 -0.40 -0.73 -0.92 0.02 -0.29 -0.01 -0.05 0.14 0.68
10127 || orf19.3040 || EHT1 || || Putative acyl-coenzymeA:ethanol O-acyltransferase; regulated by Sef1, Sfu1, and Hap43; induced by alpha pheromone in SpiderM medium; Spider biofilm induced; promoter bound by Ndt80 || 1 -2.62 -2.94 -2.35 -3.87 -0.33 -0.17 -1.25 -1.17 -2.24 -1.92 1.00 0.21 -0.19 -0.29 0.49 1.82
10128 || orf19.3040 || EHT1 || || Putative acyl-coenzymeA:ethanol O-acyltransferase; regulated by Sef1, Sfu1, and Hap43; induced by alpha pheromone in SpiderM medium; Spider biofilm induced; promoter bound by Ndt80 || 1 -3.74 -3.72 -3.74 -4.49 -0.77 -0.20 -1.70 -1.05 -2.47 -1.65 0.75 0.17 -0.50 -0.45 0.10 1.27
10129 || orf19.3040 || EHT1 || || Putative acyl-coenzymeA:ethanol O-acyltransferase; regulated by Sef1, Sfu1, and Hap43; induced by alpha pheromone in SpiderM medium; Spider biofilm induced; promoter bound by Ndt80 || 1 -3.82 -3.81 -3.67 -4.43 -0.67 -0.29 -1.65 -1.48 -2.95 -1.98 0.60 0.17 -0.79 -0.51 0.39 1.37
10130 || orf19.3628 || RSP5 || || Putative NEDD4 family E3 ubiquitin ligase; induced during infection of murine kidney, compared to growth in vitro; has murine homolog; possibly an essential gene, disruptants not obtained by UAU1 method || 1 -0.86 -0.77 -0.94 -0.88 -0.05 -0.21 -0.22 -0.23 -0.57 -0.56 0.13 0.07 -0.14 -0.16 0.21 0.46
10131 || orf19.3040 || EHT1 || || Putative acyl-coenzymeA:ethanol O-acyltransferase; regulated by Sef1, Sfu1, and Hap43; induced by alpha pheromone in SpiderM medium; Spider biofilm induced; promoter bound by Ndt80 || 1 -3.32 -2.66 -4.21 -4.01 -0.58 0.02 -1.19 -1.05 -2.08 -2.37 0.75 0.37 -0.70 -0.58 0.46 1.80
10132 || orf19.6986 || || || Has domain(s) with predicted Rab GTPase activator activity, role in regulation of Rab GTPase activity and intracellular localization || 1 -1.46 -1.42 -1.36 -1.43 -0.03 -0.44 -0.33 -0.33 -0.67 -0.97 0.19 0.40 -0.46 -0.03 0.05 0.61
10133 || orf19.6797 || || || Ortholog of C. dubliniensis CD36 : Cd36_86960, C. parapsilosis CDC317 : CPAR2_808800, Candida tenuis NRRL Y-1498 : CANTEDRAFT_113621 and Debaryomyces hansenii CBS767 : DEHA2F02486g || 1 -1.23 -0.97 -1.35 -1.38 -0.11 0.06 -0.44 -0.52 -0.50 -0.63 -0.13 0.34 -0.25 0.19 0.07 0.44
10134 || orf19.4245 || || || Protein with a predicted pleckstrin domain; Hap43-repressed gene || 1 -1.17 -1.52 -2.25 -1.91 0.13 -0.24 -0.07 -0.60 -0.79 -0.43 0.61 0.49 -0.12 -0.44 -0.05 0.79
10135 || orf19.4912 || || || Ortholog(s) have ubiquitin protein ligase binding activity, role in protein ubiquitination, ubiquitin-dependent endocytosis and Golgi apparatus, clathrin-coated vesicle, cytosol, nucleus, plasma membrane localization || 1 -1.32 -1.35 -1.55 -1.45 0.03 0.12 -0.52 -0.55 -0.35 -0.22 0.18 0.34 0.19 -0.15 0.21 0.70
10136 || orf19.1876 || || || Ortholog(s) have mRNA binding activity, role in mRNA splice site selection, positive regulation of mRNA splicing, via spliceosome and U1 snRNP, U2-type prespliceosome, commitment complex localization || 1 -1.02 -0.93 -0.86 -1.14 -0.07 0.04 -0.03 -0.30 -0.30 0.02 0.41 0.44 0.02 0.13 0.40 0.49
10137 || orf19.4010 || PAN3 || || Ortholog(s) have poly(A)-specific ribonuclease activity, role in mRNA 3'-end processing, postreplication repair and PAN complex, cytosol, nucleus localization || 1 -0.98 -0.95 -0.90 -1.01 -0.02 -0.19 -0.09 -0.31 -0.38 -0.34 0.36 0.74 -0.02 -0.12 0.48 0.81
10138 || orf19.470 || || || Ortholog(s) have RNA polymerase II activating transcription factor binding, TBP-class protein binding, chromatin binding, protein complex scaffold activity || 1 -1.19 -1.28 -0.88 -1.10 -0.42 0.18 -0.11 -0.25 -0.38 -0.57 0.05 0.66 0.06 -0.10 0.56 0.11
10139 || orf19.1876 || || || Ortholog(s) have mRNA binding activity, role in mRNA splice site selection, positive regulation of mRNA splicing, via spliceosome and U1 snRNP, U2-type prespliceosome, commitment complex localization || 1 -1.10 -1.47 -1.16 -1.08 -0.38 -0.02 -0.16 -0.47 -0.52 -0.16 0.18 0.30 -0.10 -0.07 0.35 0.17
10140 || orf19.6694 || || || Ortholog of C. dubliniensis CD36 : Cd36_73320, C. parapsilosis CDC317 : CPAR2_703860, Candida tenuis NRRL Y-1498 : CANTEDRAFT_114480 and Debaryomyces hansenii CBS767 : DEHA2C13794g || 1 -0.78 -0.92 -0.71 -0.99 -0.28 -0.28 -0.26 -0.54 -0.59 -0.26 0.24 0.24 -0.11 -0.11 0.47 -0.03
10141 || orf19.166 || ASG1 || || Gal4p family zinc-finger transcription factor with similarity to S. cerevisiae Asg1p || 1 -0.96 -0.83 -1.04 -1.50 -0.18 0.07 -0.61 -0.41 -0.47 -0.56 0.43 0.54 -0.33 -0.57 0.07 0.92
10142 || orf19.6189 || || || Chalcone related protein family; flow model biofilm induced || 1 -0.49 -0.61 -0.96 -1.20 0.01 -0.06 -0.56 -0.38 -0.59 -0.50 0.48 0.76 -0.43 -0.62 0.27 0.95
10143 || orf19.1880 || HEM15 || || Putative ferrochelatase involved in heme biosynthesis; transcript not regulated by iron levels and not affected by a yfh1 null mutation; Spider biofilm repressed || 1 -1.00 -1.19 -1.63 -1.76 -0.69 0.06 -0.06 -0.61 -0.72 -1.58 1.13 0.94 -0.76 -0.89 0.71 1.14
10144 || orf19.1880 || HEM15 || || Putative ferrochelatase involved in heme biosynthesis; transcript not regulated by iron levels and not affected by a yfh1 null mutation; Spider biofilm repressed || 1 -1.38 -1.43 -1.62 -1.88 -0.66 0.05 -0.22 -0.68 -0.73 -1.57 1.03 0.99 -1.00 -0.63 0.70 0.89
10145 || orf19.3442 || || || Putative oxidoreductase; Hap43-repressed gene || 1 -1.24 -1.30 -1.96 -2.23 -0.30 0.20 -0.14 -0.46 -0.39 -1.88 0.39 0.63 -0.49 -0.51 -0.59 0.67
10146 || orf19.1289 || SCT1 || || Putative glycerol-3-phosphate O-acyltransferase; fungal-specific (no human or murine homolog) || 1 -0.59 -0.71 -0.92 -0.91 -0.11 0.07 -0.08 -0.36 -0.29 -0.86 0.05 0.16 -0.19 -0.37 -0.19 0.49
10147 || orf19.5103 || || || Protein with a predicted phosphoglycerate mutase family domain; Hap43-repressed; clade-associated gene expression; induced by hypoxia || 1 -2.37 -2.08 -2.81 -3.49 -0.82 -0.09 -0.29 -0.64 -1.16 -2.62 1.10 0.49 -0.28 -1.01 -0.20 1.58
10148 || orf19.5103 || || || Protein with a predicted phosphoglycerate mutase family domain; Hap43-repressed; clade-associated gene expression; induced by hypoxia || 1 -2.04 -1.30 -2.66 -3.05 -0.70 0.00 -0.26 -0.45 -1.10 -2.54 1.31 0.70 -0.05 -1.12 -0.03 1.79
10149 || orf19.4738 || || || Ortholog(s) have role in protein folding in endoplasmic reticulum and integral to endoplasmic reticulum membrane localization || 1 -0.90 -0.93 -1.02 -1.57 -0.25 0.19 -0.34 -0.45 -0.61 -1.34 0.54 0.64 0.25 -0.43 -0.11 0.94
10150 || orf19.4738 || || || Ortholog(s) have role in protein folding in endoplasmic reticulum and integral to endoplasmic reticulum membrane localization || 1 -0.65 -0.74 -1.02 -1.87 -0.20 -0.00 -0.16 -0.02 -0.56 -1.23 0.61 0.43 0.37 -0.51 0.00 0.89
10151 || orf19.166 || ASG1 || || Gal4p family zinc-finger transcription factor with similarity to S. cerevisiae Asg1p || 1 -1.06 -0.98 -1.81 -2.15 0.25 0.19 -0.68 -1.03 -0.76 -1.21 0.39 0.15 0.04 -0.67 0.35 0.89
10152 || orf19.5818 || SUR2 || || Putative ceramide hydroxylase; predicted enzyme of sphingolipid biosynthesis; regulated by Tsa1, Tsa1B under H2O2 stress conditions; Spider and flow model biofilm induced || 1 -1.37 -1.38 -1.65 -2.46 0.27 0.06 -0.34 -0.94 -1.38 -1.68 1.52 0.59 -0.71 -1.03 0.62 1.67
10153 || orf19.5818 || SUR2 || || Putative ceramide hydroxylase; predicted enzyme of sphingolipid biosynthesis; regulated by Tsa1, Tsa1B under H2O2 stress conditions; Spider and flow model biofilm induced || 1 -1.29 -1.38 -2.55 -2.78 0.36 0.13 -0.57 -1.08 -1.56 -1.83 1.52 0.55 -0.74 -1.03 0.56 1.39
10154 || orf19.4911 || || || BED zinc finger protein; predicted DNA binding protein; Spider biofilm repressed || 1 -0.94 -1.10 -1.46 -1.33 0.02 0.14 -0.58 -0.40 -0.90 -1.11 0.83 0.25 0.12 -0.28 0.42 0.83
10155 || orf19.4911 || || || BED zinc finger protein; predicted DNA binding protein; Spider biofilm repressed || 1 -1.08 -1.27 -1.39 -1.27 -0.20 0.16 -0.42 -0.85 -1.45 -1.72 1.07 0.31 0.10 -0.39 0.80 0.82
10156 || orf19.3040 || EHT1 || || Putative acyl-coenzymeA:ethanol O-acyltransferase; regulated by Sef1, Sfu1, and Hap43; induced by alpha pheromone in SpiderM medium; Spider biofilm induced; promoter bound by Ndt80 || 1 -1.51 -1.18 -1.15 -1.58 -0.16 -0.24 -0.74 -0.73 -1.66 -1.73 0.56 -0.08 -0.03 -0.52 0.36 1.05
10157 || orf19.1906 || || || Protein of unknown function; flow model biofilm induced || 1 -1.03 -0.97 -2.08 -2.88 -0.80 -1.24 -0.39 -1.25 -2.08 -2.47 1.92 1.20 -0.44 -1.50 0.43 1.43
10158 || orf19.633 || CRG1 || || Methyltransferase involved in sphingolipid homeostasis, methylates a drug cantharidin; decreased expression in hyphae compared to yeast; expression regulated during planktonic growth; flow model biofilm induced; Hap43-repressed gene || 1 -1.61 -1.67 -1.74 -2.73 -0.61 -1.17 -0.14 -1.11 -0.68 -2.59 1.39 0.90 -1.02 -1.48 0.16 1.31
10159 || orf19.633 || CRG1 || || Methyltransferase involved in sphingolipid homeostasis, methylates a drug cantharidin; decreased expression in hyphae compared to yeast; expression regulated during planktonic growth; flow model biofilm induced; Hap43-repressed gene || 1 -1.43 -1.32 -1.73 -2.65 -0.36 -0.86 0.04 -0.81 -0.25 -2.86 1.67 0.99 -0.61 -1.41 0.28 1.38
10160 || orf19.5228 || RIB3 || || 3,4-Dihydroxy-2-butanone 4-phosphate synthase; homodimeric enzyme of riboflavin biosynthesis; converts ribulose 5-phosphate to L-3,4-dihydroxy-2-butanone 4-phosphate; transcription regulated on yeast-hyphal switch, macrophage interaction || 1 -1.17 -1.28 -2.19 -2.75 0.21 0.07 0.20 -0.02 -0.18 -1.61 0.47 0.17 0.18 -0.41 -0.44 0.69
10161 || orf19.391 || UPC2 || || Zn2-Cys6 transcript factor; regulator of ergosterol biosynthetic genes and sterol uptake; binds ERG2 promoter; induced by ergosterol depletion, by azoles, anaerobicity; macrophage/pseudohyphal-repressed; flow model biofilm induced || 1 -2.21 -2.05 -2.18 -2.70 -0.17 0.62 -0.44 -0.50 -0.27 -1.56 0.70 0.65 -0.83 -0.39 -1.42 1.21
10162 || orf19.391 || UPC2 || || Zn2-Cys6 transcript factor; regulator of ergosterol biosynthetic genes and sterol uptake; binds ERG2 promoter; induced by ergosterol depletion, by azoles, anaerobicity; macrophage/pseudohyphal-repressed; flow model biofilm induced || 1 -1.73 -1.92 -2.01 -2.66 -0.07 0.46 -0.35 -0.36 -0.25 -1.63 0.53 0.40 -0.26 -0.55 -1.24 1.54
10163 || orf19.4836 || URA1 || || Dihydroorotate dehydrogenase; de novo pyrimidine biosynthesis; regulated by yeast-hypha switch, Nrg1/Mig1/Tup1; flow model biofilm induced; rat catheter and Spider biofilm repressed || 1 -1.15 -1.22 -1.23 -1.52 -0.04 0.50 0.26 -0.21 0.17 -1.10 0.43 0.56 0.16 -0.36 -0.25 0.71
10164 || orf19.4836 || URA1 || || Dihydroorotate dehydrogenase; de novo pyrimidine biosynthesis; regulated by yeast-hypha switch, Nrg1/Mig1/Tup1; flow model biofilm induced; rat catheter and Spider biofilm repressed || 1 -1.56 -1.56 -1.20 -1.48 -0.17 0.57 0.25 -0.21 0.14 -1.18 0.34 0.26 -0.02 -0.40 -0.64 0.36
10165 || orf19.1219 || || || Ortholog of Spathaspora passalidarum NRRL Y-27907 : SPAPADRAFT_149713 || 1 -0.90 -0.80 -0.88 -0.84 0.44 -0.22 -0.31 -0.22 -0.17 0.32 0.28 0.42 -0.26 -0.06 0.36 0.14
10166 || orf19.2555 || URA5 || || Putative orotate phosphoribosyltransferase; protein abundance is affected by URA3 expression in the CAI-4 strain background; flucytosine induced; protein level decreased in stationary phase cultures || 1 -1.72 -1.42 -1.54 -1.09 0.23 0.57 -0.57 -0.11 -1.21 0.06 0.68 0.28 -1.07 0.07 -0.09 0.33
10167 || orf19.3341 || || || Putative tRNA-Arg synthetase; essential; genes encoding ribosomal subunits, translation factors, and tRNA synthetases are downregulated upon phagocytosis by murine macrophage; downregulated by growth in the mouse cecum || 1 -0.96 -1.00 -1.19 -1.32 0.03 0.12 -0.49 -0.18 -0.94 0.31 0.29 0.13 -0.73 0.10 0.56 0.19
10168 || orf19.2847 || || || Ortholog(s) have RNA polymerase III activity, role in tRNA transcription from RNA polymerase III promoter and DNA-directed RNA polymerase III complex, mitotic spindle pole body localization || 1 -0.77 -0.76 -1.51 -1.30 0.11 0.12 -0.25 -0.22 -0.49 0.77 0.42 -0.00 0.08 0.20 0.17 0.18
10169 || orf19.1305 || || || Ortholog(s) have tRNA (guanine) methyltransferase activity, role in tRNA methylation and mitochondrial matrix, nucleus localization || 1 -1.12 -1.29 -2.06 -1.88 -0.09 0.12 -0.33 -0.24 -1.23 0.86 0.33 -0.10 -0.32 0.01 0.11 -0.59
10170 || orf19.2500 || || || Has domain(s) with predicted transferase activity and role in biosynthetic process || 1 -0.63 -0.97 -1.73 -1.37 -0.11 -0.43 -0.21 -0.21 -0.62 0.21 -0.01 0.24 -0.50 -0.33 0.06 -0.20
10171 || orf19.2847 || || || Ortholog(s) have RNA polymerase III activity, role in tRNA transcription from RNA polymerase III promoter and DNA-directed RNA polymerase III complex, mitotic spindle pole body localization || 1 -0.67 -0.86 -1.96 -1.57 -0.21 -0.12 -0.22 -0.47 -1.17 0.36 -0.27 -0.40 -0.26 -0.57 -0.01 -0.11
10172 || orf19.4374 || PRP42 || || Putative component of the U1 snRNP, involved in splicing; ortholog of S. cerevisiae PRP42 || 1 -0.60 -0.54 -0.93 -0.66 -0.09 -0.25 0.16 -0.25 -0.53 0.02 0.08 -0.07 0.26 -0.21 0.25 0.02
10173 || orf19.150 || TIM17 || || Predicted component of the Translocase of the Inner Mitochondrial membrane (TIM23 complex), involved in protein import into mitochondria || 1 -1.47 -1.37 -2.08 -1.44 -0.33 -0.74 0.12 -0.22 -0.58 0.27 -0.03 -0.10 0.08 0.01 0.22 -0.11
10174 || orf19.6818 || || || Ortholog(s) have cytosol, mitochondrion localization || 1 -1.46 -1.55 -1.85 -1.00 -0.32 -0.44 -0.50 -0.29 -0.89 0.69 -0.25 -0.47 -0.94 -0.37 -0.14 -0.73
10175 || orf19.3303 || || || Ortholog(s) have tRNA methyltransferase activity, role in tRNA methylation, wybutosine biosynthetic process and cytosol, mitochondrion, nucleus localization || 1 -1.32 -1.52 -1.97 -1.72 0.22 0.16 -0.48 -0.84 -1.05 0.57 -0.26 -0.61 -0.84 -0.50 0.12 -0.17
10176 || orf19.3303 || || || Ortholog(s) have tRNA methyltransferase activity, role in tRNA methylation, wybutosine biosynthetic process and cytosol, mitochondrion, nucleus localization || 1 -1.49 -1.57 -1.31 -1.32 -0.09 0.34 -0.46 -0.78 -0.90 0.41 0.13 -0.25 -0.60 -0.13 0.04 -0.13
10177 || orf19.2711 || || || Similar to S. cerevisiae Elp2, an Elongator complex subunit required for modification of wobble nucleosides in tRNA; repressed in core stress response || 1 -1.22 -1.01 -1.15 -1.07 0.04 0.14 -0.59 -0.44 -0.50 0.76 -0.06 -0.17 -0.61 0.06 -0.34 -0.06
10178 || orf19.3303 || || || Ortholog(s) have tRNA methyltransferase activity, role in tRNA methylation, wybutosine biosynthetic process and cytosol, mitochondrion, nucleus localization || 1 -1.18 -1.38 -0.80 -1.15 0.12 0.28 -0.55 -0.83 -0.90 0.48 -0.12 -0.17 -0.50 -0.29 -0.40 -0.43
10179 || orf19.1310 || || || Ortholog(s) have role in nucleotide-excision repair and nucleus localization || 1 -0.99 -1.02 -0.75 -1.07 0.17 0.06 -0.39 -0.44 -0.10 -0.05 -0.28 -0.23 -0.44 0.09 -0.10 -0.10
10180 || orf19.91 || || || Protein of unknown function; flow model biofilm induced; Hap43-repressed || 1 -1.16 -1.21 -1.48 -1.11 0.43 0.62 -0.06 -0.47 -0.31 -0.57 -0.54 -0.63 -0.52 -0.23 0.44 0.14
10181 || orf19.6139 || FRE7 || || Copper-regulated cupric reductase; repressed by ciclopirox olamine or 17-beta-estradiol; induced by alkaline conditions or interaction with macrophage; Spider biofilm induced || 1 -1.83 -1.44 -2.64 -1.35 0.32 1.07 -0.74 -0.57 -0.23 -0.86 -0.91 -0.10 -0.86 0.17 0.45 0.23
10182 || orf19.6139 || FRE7 || || Copper-regulated cupric reductase; repressed by ciclopirox olamine or 17-beta-estradiol; induced by alkaline conditions or interaction with macrophage; Spider biofilm induced || 1 -2.00 -1.52 -2.38 -2.44 0.72 0.94 -0.30 -0.13 0.31 -1.02 -0.52 0.38 -0.55 0.20 0.87 0.34
10183 || orf19.1896 || SSC1 || || Heat shock protein; at yeast-form cell surface, not hyphae; antigenic; Gcn4-regulated; induced by amino acid starvation (3-AT) or by adherence to polystyrene; macrophage-repressed; sumoylation target; possibly essential || 1 -1.62 -1.62 -2.51 -2.65 1.17 0.54 -0.01 -0.09 -0.07 0.01 0.08 0.13 -1.10 -0.70 0.85 -0.04
10184 || orf19.2524 || MGE1 || || Putative mitochondrial matrix cochaperone; macrophage/pseudohyphal-repressed || 1 -1.79 -1.86 -2.06 -2.34 0.48 0.27 -0.31 -0.00 -0.35 0.03 0.18 0.08 -0.80 -0.57 0.69 -0.12
10185 || orf19.2524 || MGE1 || || Putative mitochondrial matrix cochaperone; macrophage/pseudohyphal-repressed || 1 -1.71 -1.65 -2.02 -2.22 0.57 0.26 -0.25 0.01 -0.30 -0.15 0.00 -0.03 -0.82 -0.87 0.71 -0.00
10186 || orf19.1896 || SSC1 || || Heat shock protein; at yeast-form cell surface, not hyphae; antigenic; Gcn4-regulated; induced by amino acid starvation (3-AT) or by adherence to polystyrene; macrophage-repressed; sumoylation target; possibly essential || 1 -1.76 -1.79 -2.76 -2.84 0.69 0.37 -0.39 -0.45 -0.22 -0.08 -0.21 -0.22 -1.27 -0.57 0.41 -0.28
10187 || orf19.1896 || SSC1 || || Heat shock protein; at yeast-form cell surface, not hyphae; antigenic; Gcn4-regulated; induced by amino acid starvation (3-AT) or by adherence to polystyrene; macrophage-repressed; sumoylation target; possibly essential || 1 -2.21 -2.17 -2.53 -2.56 0.60 0.61 -0.38 -0.59 -0.28 -0.18 -0.38 -0.04 -1.46 -0.87 0.60 -0.09
10188 || orf19.1896 || SSC1 || || Heat shock protein; at yeast-form cell surface, not hyphae; antigenic; Gcn4-regulated; induced by amino acid starvation (3-AT) or by adherence to polystyrene; macrophage-repressed; sumoylation target; possibly essential || 1 -1.95 -2.10 -2.41 -2.56 0.71 0.55 -0.26 -0.33 -0.10 -0.07 -0.17 0.06 -1.35 -0.68 0.57 0.00
10189 || orf19.1896 || SSC1 || || Heat shock protein; at yeast-form cell surface, not hyphae; antigenic; Gcn4-regulated; induced by amino acid starvation (3-AT) or by adherence to polystyrene; macrophage-repressed; sumoylation target; possibly essential || 1 -2.17 -2.01 -2.64 -2.41 0.53 0.70 -0.34 -0.51 -0.04 0.01 -0.11 0.06 -1.57 -0.69 0.66 0.19
10190 || orf19.7497 || || || Ortholog(s) have ubiquitin-protein ligase activity, role in protein ubiquitination involved in ubiquitin-dependent protein catabolic process and Cul3-RING ubiquitin ligase complex, cytoplasm, nucleus localization || 1 -0.57 -0.56 -0.73 -0.89 0.16 -0.05 -0.20 -0.31 -0.03 -0.02 -0.07 0.13 -0.39 -0.11 0.23 -0.04
10191 || orf19.2116 || NAT2 || || Putative N-terminal acetyltransferase; Hap43p-repressed gene; mutation confers hypersensitivity to toxic ergosterol analog || 1 -0.97 -1.22 -1.77 -1.48 -0.09 0.09 -0.27 -0.38 -0.22 -0.31 0.20 0.22 -0.87 -0.54 0.15 0.28
10192 || orf19.6432 || || || Ortholog(s) have ATPase activity, role in response to drug, ribosomal large subunit biogenesis and cytosol, preribosome, large subunit precursor localization || 1 -0.60 -0.70 -0.78 -0.82 0.06 0.19 -0.14 -0.14 -0.17 -0.05 0.11 0.24 -0.37 -0.14 0.17 0.32
10193 || orf19.974 || ROT2 || || Alpha-glucosidase II, catalytic subunit, required for N-linked protein glycosylation and normal cell wall synthesis; alkaline downregulated || 1 -0.70 -0.54 -0.75 -0.69 0.48 -0.03 0.10 0.08 0.23 -0.03 0.20 0.13 -0.25 0.03 0.25 0.15
10194 || orf19.3312 || || || Protein of unknown function; flow model and Spider biofilm repressed || 1 -1.47 -1.46 -1.52 -1.70 0.74 0.33 0.03 0.20 0.05 -0.05 0.11 0.25 -0.45 0.18 0.20 0.28
10195 || orf19.2396 || IFR2 || || Zinc-binding dehydrogenase; induced by benomyl, ciclopirox olamine, alpha pheromone, Hap43; regulated by oxidative stress via Cap1, osmotic stress via Hog1; protein present in exponential and stationary phase; rat catheter biofilm repressed || 1 -1.85 -1.95 -1.92 -2.37 0.76 0.37 0.58 0.47 0.08 -0.40 0.66 -0.02 -0.60 0.25 -0.36 -0.24
10196 || orf19.2396 || IFR2 || || Zinc-binding dehydrogenase; induced by benomyl, ciclopirox olamine, alpha pheromone, Hap43; regulated by oxidative stress via Cap1, osmotic stress via Hog1; protein present in exponential and stationary phase; rat catheter biofilm repressed || 1 -2.85 -3.04 -2.27 -2.68 0.19 0.17 0.20 -0.04 0.09 -0.41 0.13 0.42 -1.33 0.55 -0.85 -0.37
10197 || orf19.4984 || || || Has domain(s) with predicted chitin binding, chitinase activity and role in carbohydrate metabolic process, cell wall macromolecule catabolic process, chitin catabolic process || 1 -0.88 -1.06 -1.21 -1.38 0.12 -0.16 0.19 0.24 0.45 -0.35 0.11 0.01 -0.39 -0.23 -0.40 0.08
10198 || orf19.2092 || || || Putative peroxisomal cystathionine beta-lyase; Gcn4p-regulated || 1 -1.61 -1.72 -1.46 -1.23 -0.25 -0.35 0.12 -0.30 0.60 -0.85 0.03 0.07 -1.14 -0.47 0.02 0.18
10199 || orf19.6673 || HEX1 || || Beta-N-acetylhexosaminidase/chitobiase, highly glycosylated enzyme that is secreted to the periplasm and culture medium; required for full virulence; may have role in carbon or nitrogen scavenging; possibly an essential gene (UAU1 method) || 1 -1.63 -1.39 -1.46 -1.24 0.14 -0.12 -0.22 -0.32 -0.11 -0.33 0.21 0.13 -1.32 -1.02 -0.20 0.37
10200 || orf19.4467 || || || Ortholog of C. dubliniensis CD36 : Cd36_03660, C. parapsilosis CDC317 : CPAR2_106860, Candida tenuis NRRL Y-1498 : CANTEDRAFT_96694 and Debaryomyces hansenii CBS767 : DEHA2G15950g || 1 -1.40 -1.21 -0.95 -1.25 -0.50 -0.23 -0.05 -0.41 -0.07 0.02 -0.28 0.28 -0.76 -0.56 -0.06 0.27
10201 || orf19.1669 || AFG3 || || Similar to S. cerevisiae Afg3p, a subunit of the mitochondrial inner membrane m-AAA protease; likely to be essential for growth, based on an insertional mutagenesis strategy || 1 -0.81 -0.91 -0.96 -0.98 -0.20 -0.14 -0.07 -0.20 -0.10 0.22 -0.28 0.28 -0.39 -0.31 0.18 0.07
10202 || orf19.5910 || || || Putative histone acetyltransferase complex subunit; induced upon low-level peroxide stress; Spider biofilm induced || 1 -0.81 -1.05 -0.75 -0.69 0.10 -0.10 -0.62 -0.24 -0.11 0.30 -0.45 0.36 -0.70 -0.12 -0.40 -0.06
10203 || orf19.274 || TFC4 || || Putative RNA polymerase III transcription initiation factor complex (TFIIIC) subunit; induced by Mnl1 under weak acid stress; possibly essential gene, disruptants not obtained by UAU1 method || 1 -1.17 -1.40 -1.13 -0.90 -0.46 -0.22 -0.96 -0.40 -0.31 -0.43 -0.17 0.42 -0.54 0.05 -0.38 0.27
10204 || orf19.4106 || || || Ortholog of S. cerevisiae : YJR141W, C. glabrata CBS138 : CAGL0M00264g, C. dubliniensis CD36 : Cd36_20520, C. parapsilosis CDC317 : CPAR2_104880 and Candida tenuis NRRL Y-1498 : CANTEDRAFT_126860 || 1 -0.84 -1.26 -1.36 -1.32 -0.07 -0.36 -0.41 -0.25 -0.18 0.12 -0.12 0.54 -0.38 -0.08 -0.44 0.28
10205 || orf19.6532 || || || Ortholog(s) have FAD transmembrane transporter activity, role in FAD transport and mitochondrion localization || 1 -0.62 -1.19 -0.88 -1.29 -0.25 0.17 -0.44 -0.60 -0.02 -0.17 0.04 0.58 -0.54 -0.23 -0.28 0.22
10206 || orf19.6716 || ABD1 || || SAM-dependent RNA methyltransferase; methylates mRNA 5' cap; binds phosphorylated RNA Pol II C-term domain peptide; does not bind mRNA TPase and mRNA GTase (Cet1,Cgt1); functional homolog of S. cerevisiae Abd1; rat catheter biofilm induced || 1 -0.43 -0.52 -0.35 -0.52 -0.09 -0.14 -0.20 -0.31 -0.15 -0.19 -0.05 0.40 -0.26 -0.11 0.25 0.25
10207 || orf19.5780 || || || Putative protein of unknown function; Hap43p-repressed gene || 1 -0.72 -0.75 -0.70 -0.90 0.08 0.03 -0.15 -0.49 0.05 -0.17 -0.04 0.60 -0.56 0.02 0.29 0.18
10208 || orf19.5525 || || || Putative oxidoreductase; protein levels affected by URA3 expression in CAI-4 strain background; Efg1, Efh1 regulated; Rgt1-repressed; protein present in exponential and stationary growth phase yeast; rat catheter biofilm repressed || 1 -1.77 -1.76 -0.83 -1.08 -0.06 0.29 -0.12 -0.32 -0.47 -0.62 0.37 0.27 -0.72 -0.30 0.31 0.25
10209 || orf19.3876 || ZCF19 || || Predicted Zn(II)2Cys6 transcription factor || 1 -1.72 -1.39 -1.70 -0.73 -0.56 0.12 -0.56 -0.79 -0.69 0.15 -0.32 0.89 -0.58 -0.56 0.54 0.36
10210 || orf19.5587 || || || Protein of unknown function; transcript is upregulated in clinical isolates from HIV+ patients with oral candidiasis || 1 -2.51 -2.22 -1.13 -1.84 -0.37 0.27 -1.06 -1.14 -0.17 -0.76 0.26 0.88 -2.11 -0.67 0.82 0.23
10211 || orf19.3954 || PSD2 || || Ortholog(s) have phosphatidylserine decarboxylase activity, role in phosphatidylcholine biosynthetic process, phosphatidylethanolamine biosynthetic process and cell division site, cytosol, endosome localization || 1 -0.95 -1.29 -0.93 -0.69 -0.30 -0.00 -0.50 -0.41 0.09 0.02 0.06 0.43 -0.73 -0.32 0.33 -0.45
10212 || orf19.1217 || || || Ortholog(s) have ribosome binding, ubiquitin-protein ligase activity and role in chromatin modification, chromatin silencing at telomere, protein ubiquitination, ribosome-associated ubiquitin-dependent protein catabolic process || 1 -1.12 -1.03 -1.30 -0.81 -0.19 -0.19 -0.32 -0.31 -0.18 0.17 0.01 0.39 -1.07 -0.09 0.27 -0.13
10213 || orf19.880 || || || Ortholog(s) have role in cargo loading into COPII-coated vesicle and COPII vesicle coat, cytosol, mating projection tip localization || 1 -0.79 -0.70 -0.46 -0.25 -0.24 -0.03 -0.28 -0.31 -0.06 0.16 -0.03 0.35 -0.39 0.03 0.09 0.08
10214 || orf19.3417 || ACF2 || || Putative endo-1,3-beta-glucanase; fungal-specific (no human or murine homolog) || 1 -1.18 -1.03 -1.17 -0.80 0.06 -0.03 -0.57 -0.38 -0.46 -0.17 0.30 0.62 -0.94 0.03 0.47 0.28
10215 || orf19.5032 || SIM1 || || Adhesin-like protein; involved in cell wall maintenance, redundant with Sun41; possibly secreted; macrophage-repressed; repressed by Rim101, Cyr1, Ras1; Spider biofilm induced || 1 -1.49 -1.60 -1.41 -0.63 -0.27 -0.10 -0.44 -0.74 -0.81 -0.43 0.25 0.61 -1.40 -0.40 0.09 0.34
10216 || orf19.5032 || SIM1 || || Adhesin-like protein; involved in cell wall maintenance, redundant with Sun41; possibly secreted; macrophage-repressed; repressed by Rim101, Cyr1, Ras1; Spider biofilm induced || 1 -1.43 -1.57 -1.33 -0.68 -0.25 -0.16 -0.40 -0.73 -0.76 -0.44 0.27 0.58 -1.41 -0.37 0.16 0.34
10217 || orf19.3417 || ACF2 || || Putative endo-1,3-beta-glucanase; fungal-specific (no human or murine homolog) || 1 -1.78 -1.87 -1.13 -0.46 -0.10 -0.34 -0.57 -0.49 -0.55 -0.05 0.33 0.49 -1.18 -0.15 0.27 0.38
10218 || orf19.3045 || || || Predicted aldehyde dehydrogenase domain; virulence-group-correlated expression || 1 -1.28 -1.52 -1.08 -0.44 -0.83 -0.39 -0.92 -0.36 -0.95 0.11 0.35 0.48 -1.56 -0.29 -0.02 0.35
10219 || orf19.4848 || SKI3 || || Ortholog(s) have role in negative regulation of G2/M transition of mitotic cell cycle, nuclear-transcribed mRNA catabolic process, 3'-5' exonucleolytic nonsense-mediated decay, nuclear-transcribed mRNA catabolic process, non-stop decay || 1 -0.56 -0.68 -0.35 -0.22 -0.37 -0.08 -0.22 -0.13 -0.33 -0.27 -0.04 0.44 -0.35 -0.05 -0.03 0.43
10220 || orf19.6671 || LAP4 || || Protein similar to aminopeptidase I; mutation confers hypersensitivity to amphotericin B; transcript regulated in macrophage response; flow model biofilm induced || 1 -0.84 -0.75 -0.61 -0.48 -0.18 -0.28 -0.56 -0.30 -0.07 -0.70 0.33 0.54 -0.77 -0.07 0.04 0.51
10221 || orf19.835 || || || Ortholog(s) have role in nucleosome mobilization and Ino80 complex, cytosol localization || 1 -0.69 -0.63 -0.43 -0.52 -0.47 -0.14 -0.13 -0.25 -0.23 -0.69 0.34 0.49 -0.25 -0.26 0.06 0.58
10222 || orf19.6527 || || || Pheromone-regulated protein (Prm10) of S. cerevisiae; colony morphology-related gene regulation by Ssn6; induced by Mnl1 under weak acid stress; possibly essential gene, disruptants not obtained by UAU1 method; Spider biofilm induced || 1 -1.10 -1.23 -0.52 -0.98 -0.54 0.16 -0.36 -0.84 -0.04 -0.87 0.51 0.90 -0.90 -0.64 -0.02 0.44
10223 || orf19.5980 || || || Protein of unknown function; Hap43-repressed gene || 1 -0.50 -0.89 -0.44 -0.86 -0.44 0.10 -0.08 -0.26 0.16 -0.62 0.27 0.10 -0.25 -0.30 -0.00 0.51
10224 || orf19.2277 || TPK2 || || cAMP-dependent protein kinase catalytic subunit; isoform of Tpk1; needed for epithelial cell damage, engulfment and oral (not systemic) virulence in mice; control of morphogenesis and stress response; rat catheter, Spider biofilm repressed || 1 -1.04 -1.16 -0.48 -0.60 -0.38 0.20 -0.37 -0.16 0.04 -0.55 -0.16 0.12 -0.31 0.06 0.16 0.38
10225 || orf19.2277 || TPK2 || || cAMP-dependent protein kinase catalytic subunit; isoform of Tpk1; needed for epithelial cell damage, engulfment and oral (not systemic) virulence in mice; control of morphogenesis and stress response; rat catheter, Spider biofilm repressed || 1 -0.97 -1.13 -0.86 -0.82 -0.28 0.16 -0.42 -0.06 -0.16 -0.75 0.07 0.48 -0.36 0.19 0.30 -0.12
10226 || orf19.2966 || || || Predicted dienelactone hydrolase domain; clade-associated gene expression; farnesol-downregulated; rat catheter biofilm repressed || 1 -0.40 -0.46 -0.81 -0.87 0.15 0.27 0.07 -0.05 -0.25 -0.80 0.08 0.09 -0.22 0.25 0.09 0.13
10227 || orf19.5602 || BMT6 || || Beta-mannosyltransferase; beta-1,2-mannosylation of phospholipomannan; member of a 9-member family including Bmt1, Bmt2, Bmt3, and Bmt4 with roles in mannosylation of cell wall phosphopeptidomannan; flow model biofilm induced || 1 -1.06 -1.36 -1.62 -1.85 0.36 0.36 0.12 -0.59 -0.58 -1.71 -0.58 -0.37 0.72 0.16 0.78 0.93
10228 || orf19.5890 || || || Ortholog of C. dubliniensis CD36 : Cd36_84350, C. parapsilosis CDC317 : CPAR2_806070, Candida tenuis NRRL Y-1498 : CANTEDRAFT_133308 and Debaryomyces hansenii CBS767 : DEHA2F11682g || 1 -0.68 -0.79 -0.88 -1.36 0.26 -0.08 -0.01 -0.16 0.00 -0.78 -0.17 -0.30 0.31 -0.08 0.27 0.28
10229 || orf19.5552 || || || Putative transcriptional regulator of ribonucleotide reductase genes; Spider biofilm induced || 1 -0.62 -0.90 -0.83 -1.13 0.32 -0.35 0.04 -0.32 -0.02 -0.84 -0.23 0.03 0.04 0.04 0.56 0.76
10230 || orf19.1847 || ARO10 || || Aromatic decarboxylase; Ehrlich fusel oil pathway of aromatic alcohol biosynthesis; alkaline repressed; protein abundance affected by URA3 expression in CAI-4 strain; Spider biofilm induced || 1 -0.85 -0.93 -1.18 -1.71 0.47 -0.41 -0.39 -1.02 -0.15 -1.34 -0.00 0.90 0.59 0.05 0.61 0.68
10231 || orf19.1847 || ARO10 || || Aromatic decarboxylase; Ehrlich fusel oil pathway of aromatic alcohol biosynthesis; alkaline repressed; protein abundance affected by URA3 expression in CAI-4 strain; Spider biofilm induced || 1 -1.95 -1.51 -2.71 -3.10 0.36 -0.47 -0.55 -1.61 -0.39 -2.04 -0.02 0.85 0.68 0.41 0.61 0.67
10232 || orf19.5586 || || || Ortholog(s) have phosphatidylinositol-3,5-bisphosphate 5-phosphatase activity, role in phosphatidylinositol dephosphorylation and PAS complex, cytosol, extrinsic to membrane, fungal-type vacuole membrane localization || 1 -0.35 -0.49 -0.90 -1.27 -0.07 -0.46 0.13 -0.29 -0.12 -0.59 -0.31 0.27 0.13 0.21 -0.17 0.39
10233 || orf19.3737 || || || Protein with a Vps9 vacuolar protein sorting protein domain; Hap43-repressed; repressed by ciclopirox olamine; Spider biofilm induced || 1 -0.67 -0.81 -1.12 -1.22 0.57 -0.39 -0.36 -0.66 -0.49 -0.43 -0.04 -0.12 -0.09 -0.17 0.38 0.33
10234 || orf19.1994 || || || Ortholog(s) have phosphatidylinositol-3-phosphate binding activity, role in retrograde transport, endosome to Golgi and endosome localization || 1 -0.46 -0.56 -0.83 -1.29 0.78 0.16 -0.71 -0.94 -0.74 -0.65 0.12 -0.11 -0.08 -0.21 0.28 0.16
10235 || orf19.3737 || || || Protein with a Vps9 vacuolar protein sorting protein domain; Hap43-repressed; repressed by ciclopirox olamine; Spider biofilm induced || 1 -0.40 -0.28 -0.46 -0.52 0.50 -0.01 -0.42 -0.38 -0.53 -0.48 0.13 -0.05 0.06 0.08 0.35 0.31
10236 || orf19.1861 || || || Protein of unknown function; flow model biofilm induced || 1 -1.21 -1.27 -0.79 -1.16 0.76 1.34 -1.07 -1.07 -0.41 -0.86 0.55 0.16 0.41 0.25 1.03 0.62
10237 || orf19.1861 || || || Protein of unknown function; flow model biofilm induced || 1 -1.74 -1.48 -0.93 -1.25 0.67 0.99 -1.43 -1.20 -0.90 -1.20 0.46 0.13 0.29 0.30 0.94 0.57
10238 || orf19.3712 || || || Protein of unknown function; induced by Mnl1 under weak acid stress; flow model biofilm induced; Spider biofilm induced || 1 -1.29 -1.31 -0.66 -0.79 0.02 0.66 -0.64 -1.31 -1.39 -1.46 0.28 -0.43 -0.12 0.11 0.59 0.76
10239 || orf19.5634 || FRP1 || || Ferric reductase; alkaline-induced by Rim101; iron-chelation-induced by CCAAT-binding factor; fluconazole-repressed; ciclopirox-, hypoxia-, Hap43-induced; colony morphology-related regulation by Ssn6; Spider and flow model biofilm induced || 1 -1.98 -1.63 -1.79 -1.60 0.32 0.78 -2.21 -2.55 -2.90 -2.47 -0.35 -0.36 -0.34 0.59 0.95 1.36
10240 || orf19.3977 || || || Protein with a role in translation; flow model biofilm repressed || 1 -0.17 -0.14 -0.63 -0.30 0.68 0.59 -0.39 -0.25 -1.00 -0.11 0.61 -0.00 -0.71 -0.29 0.38 0.20
10241 || orf19.6055 || || || Ortholog of C. dubliniensis CD36 : Cd36_00460, C. parapsilosis CDC317 : CPAR2_800010, Candida tenuis NRRL Y-1498 : CANTEDRAFT_125085 and Debaryomyces hansenii CBS767 : DEHA2D09086g || 1 -0.49 -0.38 -0.84 -0.89 0.95 0.63 -1.19 -0.63 -1.11 -0.54 0.51 0.42 -0.93 -0.62 0.55 0.93
10242 || orf19.6055 || || || Ortholog of C. dubliniensis CD36 : Cd36_00460, C. parapsilosis CDC317 : CPAR2_800010, Candida tenuis NRRL Y-1498 : CANTEDRAFT_125085 and Debaryomyces hansenii CBS767 : DEHA2D09086g || 1 -0.65 -0.70 -0.53 -0.88 0.68 0.45 -1.62 -0.98 -1.40 -0.93 0.34 0.37 -1.31 -0.71 0.36 1.05
10243 || orf19.3977 || || || Protein with a role in translation; flow model biofilm repressed || 1 -0.49 -0.52 -0.56 -0.61 0.54 0.77 -0.92 -0.74 -1.21 -0.18 0.36 0.15 -1.58 -0.71 0.40 0.44
10244 || orf19.1543 || OPI1 || || Leucine zipper transcription factor; repressor of INO1 involved in inositol biosynthesis; functional homolog of S. cerevisiae Opi1; has putative Opi1-Sin3 interaction domain; interacts with ScSin3, but not CaSin3 || 1 -0.41 -0.23 -1.43 -0.90 0.54 0.26 -1.32 -1.18 -2.38 -0.18 0.63 0.34 -1.24 -0.96 0.50 0.37
10245 || orf19.2867 || || || Ortholog(s) have phosphatidylinositol-3-phosphate binding, protein transporter activity and role in ascospore formation, intracellular protein transport, protein retention in Golgi apparatus, retrograde transport, endosome to Golgi || 1 -0.10 -0.12 -0.24 -0.48 0.27 -0.05 -0.50 -0.48 -0.26 -0.24 0.16 0.37 -0.41 -0.14 0.51 0.50
10246 || orf19.1994 || || || Ortholog(s) have phosphatidylinositol-3-phosphate binding activity, role in retrograde transport, endosome to Golgi and endosome localization || 1 -0.37 -0.34 -0.72 -1.09 0.67 0.26 -0.60 -1.21 -0.83 -0.34 0.34 0.59 -0.22 -0.02 0.34 0.91
10247 || orf19.6842 || TUS1 || || Putative guanine nucleotide exchange factor; induced by Mnl1 under weak acid stress; Spider biofilm induced || 1 -0.73 -0.60 -0.43 -0.49 0.77 0.27 -0.97 -0.82 -0.44 -0.67 -0.02 0.38 -0.49 0.15 0.34 0.63
10248 || orf19.4251 || ZCF22 || || Predicted Zn(II)2Cys6 transcription factor || 1 -0.46 -0.16 -0.75 -0.65 0.40 0.20 -0.69 -0.58 -0.31 -1.04 0.46 0.55 -0.70 -0.49 -0.34 0.12
10249 || orf19.5798 || LIG4 || || DNA ligase; mRNA detected in yeast-form and pseudohyphal cells, induced upon hyphal induction; suppresses S. cerevisiae ime1-1 mutant IME2 transcription defect; required for wild-type filamentous growth and wild-type pathogenesis || 1 -0.73 -0.81 -1.66 -0.89 0.78 0.67 -1.03 -0.98 -0.10 -1.05 0.50 0.44 -1.59 -0.01 0.62
10250 || orf19.5821 || || || Ortholog of S. cerevisiae : YML002W, C. glabrata CBS138 : CAGL0L07634g, C. dubliniensis CD36 : Cd36_17530, C. parapsilosis CDC317 : CPAR2_212430 and Candida tenuis NRRL Y-1498 : CANTEDRAFT_128807 || 1 -0.57 -0.30 -0.63 -0.37 0.37 0.07 -0.40 -0.44 -0.18 -0.47 -0.04 0.21 -0.67 -0.35 0.10 0.07
10251 || orf19.3269 || GSL2 || || Protein similar to beta-1,3-glucan synthase; 16 predicted membrane-spanning regions; transcript regulated by Nrg1; very low gene expression in yeast-form and hyphal cells || 1 -1.53 -1.59 -0.48 -0.74 0.46 0.62 -0.95 -0.56 -0.49 -0.85 -0.41 -0.14 -0.94 -1.00 -0.54 0.34
10252 || orf19.3269 || GSL2 || || Protein similar to beta-1,3-glucan synthase; 16 predicted membrane-spanning regions; transcript regulated by Nrg1; very low gene expression in yeast-form and hyphal cells || 1 -0.82 -1.04 -0.48 -0.43 0.46 0.59 -0.50 -0.39 -0.83 -0.83 -0.24 -0.17 -0.68 -0.40 -0.53 -0.28
10253 || orf19.3854 || || || Ortholog of S. cerevisiae Sat4; amphotericin B induced; clade-associated gene expression; Spider biofilm induced || 1 -0.44 -0.42 -0.20 0.12 0.09 0.58 -0.78 -1.04 -0.97 -0.43 -0.25 0.29 -0.65 -0.06 0.07 -0.03
10254 || orf19.4199 || SLY41 || || Protein involved in ER-to-Golgi transport; rat catheter and Spider biofilm induced || 1 -0.47 -0.65 -0.56 -0.13 0.43 0.48 -0.84 -1.17 -0.73 -0.29 -0.09 0.51 -0.87 0.16 0.29 -0.01
10255 || orf19.6475 || || || Protein of unknown function; flow model biofilm induced || 1 -1.26 -1.06 -0.78 0.55 0.23 -1.16 -1.31 -1.55 -0.29 -0.00 0.83 -1.30 -0.47 -0.09 0.04
10256 || orf19.6018 || LRO1 || || Acyltransferase that catalyzes diacylglycerol esterification of phospholipids; role in lipid storage, triglyceride biosynthesis; flow model biofilm repressed || 1 -0.61 -0.73 -0.49 -0.33 0.01 0.61 -0.87 -0.77 -0.86 -0.31 0.10 0.77 -0.81 0.08 0.57 0.60
10257 || orf19.4689 || PGA57 || || Putative GPI-anchored protein; Hap43p-induced gene || 1 -2.07 -1.92 -2.10 -0.85 -0.21 0.71 -1.44 -2.31 -1.92 -0.78 0.11 0.37 -0.76 0.24 0.16 -0.04
10258 || orf19.3218 || || || Putative multidrug resistance protein; upregulated by Efg1p || 1 -0.56 -0.66 -0.68 -0.53 0.38 0.27 -0.41 -0.43 -0.34 -0.27 -0.40 0.22 -1.30 -0.83 0.01 0.17
10259 || orf19.6515 || HSP90 || || Essential chaperone, regulates several signal transduction pathways and temperature-induced morphogenesis; activated by heat shock, stress; localizes to surface of hyphae, not yeast cells; mediates echinocandin and biofilm azole resistance || 1 -0.68 -0.77 -0.69 -0.42 -0.14 0.28 -0.35 -0.23 -0.22 -0.30 0.06 -0.06 -0.91 -0.57 0.13 -0.28
10260 || orf19.1621 || GPA2 || || G-protein alpha subunit; regulates filamentous growth, copper resistance; involved in cAMP-mediated glucose signaling; reports differ on role in cAMP-PKA pathway, MAP kinase cascade; Gpr1 C terminus binds Gpa2; regulates HWP1 and ECE1 || 1 -0.51 -0.36 -0.61 -0.15 0.03 0.30 -0.53 -0.20 -0.22 -0.16 -0.04 0.12 -0.52 -0.23 0.10 -0.15
10261 || orf19.2498 || || || Predicted ubiquitin-protein ligase; Hap43-repressed gene; oxidative stress-induced via Cap1; flow model biofilm induced || 1 -0.68 -0.54 -0.30 -0.47 -0.05 0.08 -0.61 -0.68 -0.06 -0.87 -0.04 -0.09 -0.30 -0.34 0.50 0.34
10262 || orf19.6800 || POS5 || || Protein similar to S. cerevisiae Pos5p, a mitochondrial NADH kinase involved in the oxidative stress response; planktonic growth-induced gene; likely to be essential for growth, based on an insertional mutagenesis strategy || 1 0.02 -0.05 -0.87 -1.18 -0.03 -0.06 -0.83 -0.90 -0.95 -1.49 -0.67 -0.47 -0.55 -0.56 -0.05 0.15
10263 || orf19.3266 || || || Ortholog of C. dubliniensis CD36 : Cd36_25930, C. parapsilosis CDC317 : CPAR2_800910, Candida tenuis NRRL Y-1498 : CANTEDRAFT_132053 and Debaryomyces hansenii CBS767 : DEHA2E17160g || 1 -0.63 -0.62 -0.59 -0.86 -0.20 -0.42 -1.12 -0.75 -1.27 -0.80 -0.13 -0.26 -0.71 -0.34 -0.13 0.17
10264 || orf19.5635 || PGA7 || || GPI-linked hyphal surface antigen; induced by ciclopirox olamine, ketoconazole, Rim101 at pH 8; Hap43, fluconazole; flow model biofilm induced; Spider biofilm induced; required for RPMI biofilm; Bcr1-induced in a/a biofilm || 1 -1.40 -1.60 -0.93 -1.05 -0.03 0.23 -1.79 -1.40 -1.32 -2.28 -0.64 -0.92 -0.18 -0.11 0.20 0.19
10265 || orf19.7114 || CSA1 || || Surface antigen on elongating hyphae and buds; strain variation in repeat number; ciclopirox, filament induced, alkaline induced by Rim101; Efg1-, Cph1, Hap43-regulated; required for WT RPMI biofilm formation; Bcr1-induced in a/a biofilms || 1 -0.66 -0.59 -0.55 -0.94 -0.04 0.02 -0.81 -0.84 -0.55 -1.26 -0.53 -0.14 -0.13 -0.21 -0.35 0.18
10266 || orf19.74 || SEC5 || || Predicted exocyst component; ortholog of S. cerevisiae Sec5p; merged with orf19.75 in Assembly 21 || 1 -0.32 -0.30 -0.68 -0.65 -0.02 -0.32 -0.38 -0.70 -0.61 -0.79 -0.04 -0.12 -0.27 -0.27 0.24 0.12
10267 || orf19.7389 || REV3 || || Ortholog(s) have DNA-directed DNA polymerase activity, role in error-free translesion synthesis, error-prone translesion synthesis and cytosol, mitochondrion, nuclear chromatin, nucleus, zeta DNA polymerase complex localization || 1 -0.81 -0.89 -1.00 -1.22 -0.17 -0.02 -0.71 -1.04 -0.76 -1.33 -0.56 -0.08 -0.20 -0.48 0.36 0.03
10268 || orf19.3712 || || || Protein of unknown function; induced by Mnl1 under weak acid stress; flow model biofilm induced; Spider biofilm induced || 1 -1.27 -1.53 -1.33 -1.17 -0.17 0.18 -0.86 -1.48 -1.89 -1.97 -0.14 -1.04 -0.16 -0.51 0.41 0.02
10269 || orf19.3117 || CSA2 || || Extracellular-associated protein; repressed by Rim101 at pH 8; regulated by Tsa1, Tsa1B in minimal media at 37 deg; induced by ketoconazole, nitric oxide, Hap43; required for normal RPMI biofilm formation; Bcr1 induced in RPMI || 1 -1.79 -2.03 -2.07 -2.04 -0.63 0.01 -2.60 -2.58 -2.79 -2.62 -1.17 -1.61 -0.82 -1.14 0.65 0.94
10270 || orf19.5636 || RBT5 || || GPI-linked cell wall protein; hemoglobin utilization; Rfg1, Rim101, Tbf1, Fe regulated; Sfu1, Hog1, Tup1, serum, alkaline pH, antifungal drugs, geldamycin repressed; Hap43 induced; required for RPMI biofilms; Spider biofilm induced || 1 -2.62 -2.72 -3.20 -3.73 -1.24 -0.41 -2.11 -2.07 -4.15 -3.42 -1.07 -2.05 -0.72 -1.88 1.51 1.79
10271 || orf19.5636 || RBT5 || || GPI-linked cell wall protein; hemoglobin utilization; Rfg1, Rim101, Tbf1, Fe regulated; Sfu1, Hog1, Tup1, serum, alkaline pH, antifungal drugs, geldamycin repressed; Hap43 induced; required for RPMI biofilms; Spider biofilm induced || 1 -0.71 -0.72 -1.68 -1.78 -1.10 -0.17 -1.12 -1.56 -1.93 -2.57 -1.02 -1.28 -0.24 -1.28 0.65 1.05
10272 || orf19.646 || GLN1 || || Putative glutamate synthase; regulated by Tsa1, Tsa1B under H2O2 stress conditions; Spider biofilm induced || 1 -0.26 -0.19 -0.86 -0.62 -0.65 -0.07 -0.39 -0.85 -1.07 -1.18 -0.52 -0.55 -0.35 -0.58 0.11 0.22
10273 || orf19.4024 || RIB5 || || Putative riboflavin synthase; fungal-specific (no human or murine homolog); farnesol-downregulated; protein present in exponential and stationary growth phase yeast cultures || 1 -0.22 -0.24 -0.59 -0.40 -0.06 -0.07 -0.05 -0.25 -0.38 -0.59 -0.20 -0.21 -0.39 -0.39 0.23 -0.14
10274 || orf19.3944 || GRR1 || || F-box protein component of the SCF ubiquitin-ligase complex required for cell cycle progression; involved in negative control of pseudohyphal growth; Spider biofilm induced || 1 -0.37 -0.59 -1.06 -0.89 -0.20 -0.29 -0.46 -0.63 -0.92 -1.18 -0.28 -0.54 -0.34 -0.96 -0.12 -0.22
10275 || orf19.5533 || || || Ortholog(s) have guanyl-nucleotide exchange factor activity, ubiquitin binding activity || 1 -0.64 -0.68 -0.86 -0.48 0.00 -0.34 -0.75 -0.67 -0.93 -0.94 -0.74 -0.38 -0.43 -0.53 -0.01 -0.25
10276 || orf19.131 || || || Ortholog of C. dubliniensis CD36 : Cd36_61330, C. parapsilosis CDC317 : CPAR2_602800, Candida tenuis NRRL Y-1498 : CANTEDRAFT_94450 and Debaryomyces hansenii CBS767 : DEHA2F15554g || 1 -0.44 -0.49 -0.27 -0.41 0.20 -0.05 -0.20 -0.59 -0.49 -0.69 -0.35 -0.28 -0.25 -0.49 0.01 -0.15
10277 || orf19.881 || DFG16 || || Rim101 pathway protein that acts in Rim101 processing; regulates filamentation in response to alkaline pH; required for host tissue invasion during infection; flow model biofilm induced || 1 -0.69 -0.73 -0.80 -0.75 0.25 -0.20 -0.56 -0.87 -0.32 -0.84 -0.34 -0.47 -0.37 -0.55 0.08 -0.52
10278 || orf19.2242 || PRB1 || || Endoprotease B; regulated by heat, carbon source (GlcNAc-induced), nitrogen, macrophage response, human neutrophils; similar to (does not replace) S. cerevisiae vacuolar B protease Prb1p; flow model biofilm induced; Spider biofilm induced || 1 -1.00 -1.16 -1.10 -1.37 0.26 0.22 -0.61 -1.46 -0.12 -1.37 -1.12 -0.13 -0.57 -0.57 0.31 0.09
10279 || orf19.6640 || TPS1 || || Trehalose-6-phosphate synthase; role in hyphal growth and virulence in mouse systemic infection; induced in presence of human neutrophils; macrophage/pseudohyphal-repressed after 16h; stationary phase enriched protein; Hap43-repressed || 1 -1.28 -1.41 -0.89 -1.62 -0.20 0.60 -0.38 -1.08 -0.40 -2.09 -0.62 -0.04 -0.50 -0.82 0.12 0.18
10280 || orf19.6474 || || || Protein with chitin synthesis regulation, resistance to Congo red domain; membrane-localized protein; Spider biofilm induced || 1 -0.57 -0.45 -0.56 -0.72 -0.07 0.97 -0.90 -1.21 -0.89 -0.99 -0.30 0.79 -0.22 -0.32 0.05 -0.30
10281 || orf19.3644 || || || Protein of unknown function; Cyr1-repressed; rat catheter and Spider biofilm induced || 1 -0.54 -0.46 -0.61 -0.25 0.21 0.68 -0.79 -0.86 -0.67 -0.61 -0.17 0.82 -0.36 -0.46 0.72 0.02
10282 || orf19.6706 || GYP7 || || Protein similar to S. cerevisiae Gyp7p (GTPase-activating protein for Ypt1p); caspofungin-induced || 1 -0.29 -0.34 0.05 -0.17 0.36 0.61 -0.65 -0.87 -0.32 -0.94 -0.79 -0.15 -1.31 -0.15 0.41 0.24
10283 || orf19.1461 || || || S. pombe ortholog SPCC576.01c is a predicted sulfonate dioxygenase; possibly transcriptionally regulated upon hyphal formation; Spider biofilm induced || 1 -0.73 -0.93 -0.12 -0.27 0.59 0.94 -1.12 -1.37 -0.62 -0.94 -1.00 0.00 -1.39 -0.44 0.95 0.32
10284 || orf19.4610 || || || Predicted metallocarboxypeptidase; role in proteolysis; rat catheter biofilm repressed || 1 -0.43 -0.76 -0.08 -0.26 0.18 0.39 -0.29 -0.56 -0.38 -0.76 -0.37 0.04 -0.56 -0.60 0.43 0.27
10285 || orf19.24 || RTA2 || || Flippase; sphingolipid long chain base release; mediates calcineurin-dependent resistance to azoles; stress-associate; Plc1, Ca2+, calcineurin-regulated; ketoconazole, caspofungin induced; Spider biofilm induced; flow biofilm repressed || 1 -1.01 -1.31 -0.02 -0.55 -0.03 0.38 -0.84 -0.96 -0.60 -0.54 -0.17 -0.15 -1.32 -1.15 1.26 0.47
10286 || orf19.5095 || || || Putative oxysterol-binding protein; caspofungin induced; possibly an essential gene, disruptants not obtained by UAU1 method || 1 -0.45 -0.40 -0.29 -0.47 -0.14 0.53 -0.43 -0.67 -0.29 -0.38 -0.29 0.28 -0.63 -0.18 0.69 0.10
10287 || orf19.5095 || || || Putative oxysterol-binding protein; caspofungin induced; possibly an essential gene, disruptants not obtained by UAU1 method || 1 -0.45 -0.62 -0.29 -0.49 -0.18 0.44 -0.55 -0.61 -0.22 -0.48 -0.19 0.14 -0.81 -0.38 0.49 0.08
10288 || orf19.1255 || ZCF5 || || Zn(II)2Cys6 transcription factor; colony morphology-related gene regulation by Ssn6 || 1 -0.57 -0.97 -0.19 -0.21 0.18 0.70 -0.81 -0.53 -0.47 -0.19 -0.40 0.33 -1.28 -0.56 -0.00 -0.09
10289 || orf19.2882 || XUT1 || || Putative high-affinity, high-capacity xanthine-uric acid/H+ symporter; similar to A. nidulans UapA; member of the Nucleobase-Ascorbate Transporter/Nucleobase-Cation Symporter (NAT/NCS2) family; rat catheter biofilm induced || 1 -0.77 -0.86 -0.37 -0.21 0.24 1.15 -0.70 -1.03 -0.69 -0.68 -1.03 0.67 -1.21 -1.30 0.84 0.09
10290 || orf19.2076 || || || Protein of unknown function; S. pombe ortholog SPAC7D4.05 encodes a predicted hydrolase; Hap43-repressed; Spider biofilm induced || 1 -0.71 -0.70 -0.36 -0.54 0.23 1.04 -0.99 -1.38 -0.10 -0.75 -0.50 0.70 -1.42 -1.04 0.57 0.52
10291 || orf19.1183 || || || Ortholog(s) have fungal-type vacuole localization || 1 -1.13 -1.17 -0.22 -0.41 0.68 1.72 -1.60 -1.83 -0.85 -0.93 -0.48 0.39 -1.67 -1.09 0.60 0.47
10292 || orf19.5770 || OPT8 || || Oligopeptide transporter; similar to Opt1 and to S. cerevisiae Ygl114wp, but not other OPTs; induced by nitric oxide, amphotericin B; expression of OPT6, 7, 8 does not complement mutants lacking Opt1, Opt2, and Opt3; Spider biofilm induced || 1 -1.09 -0.95 -0.85 -0.15 0.94 1.75 -1.01 -1.07 -1.19 -0.70 -0.53 0.41 -1.77 -1.61 0.49 0.04
10293 || orf19.1656 || || || Protein with a predicted FYVE/PHD zinc finger domain; Hap43-repressed; Spider biofilm induced || 1 -1.12 -0.94 -0.91 -0.67 1.31 1.84 -0.94 -1.44 -0.83 -0.47 -0.55 0.48 -0.97 -1.02 0.52 -0.11
10294 || orf19.3839 || SAP10 || || Secreted aspartyl protease; roles in adhesion, virulence (RHE model), cell surface integrity; distinct specificity from Sap9; at cell membrane and wall; GPI-anchored; induced in low iron; Tbf1-activated; Spider biofilm induced || 1 -1.41 -1.62 -0.73 -0.88 0.54 0.85 -0.36 -1.07 -0.07 -0.85 -0.31 0.77 -1.49 -0.46 0.69 -0.07
10295 || orf19.246 || || || Predicted metalloendopeptidase; Spider biofilm induced || 1 -1.72 -1.85 -1.13 -0.94 0.62 1.84 -1.35 -1.45 -0.55 -1.37 -0.30 1.05 -1.39 -1.26 0.56 0.08
10296 || orf19.3402 || FPG1 || || Formamidopyrimidine DNA glycosylase, involved in repair of gamma-irradiated DNA; Hap43p-repressed gene || 1 -0.59 -0.69 -0.14 -0.09 0.18 0.59 -0.41 -0.23 -0.07 -0.44 -0.40 0.15 -0.57 -0.25 0.14 0.09
10297 || orf19.1952 || || || Protein not essential for viability; merged with orf19.1953 in Assembly 21 || 1 -0.64 -0.74 0.02 -0.31 0.21 0.46 -0.37 -0.23 -0.08 -0.25 -0.19 0.22 -0.46 -0.02 0.33 0.12
10298 || orf19.3988 || || || Putative adhesin-like protein; induced by Mnl1 under weak acid stress; rat catheter and Spider biofilm induced || 1 -1.75 -2.37 -0.30 -0.71 1.71 2.00 -2.24 -1.91 -0.92 0.04 -1.22 0.59 -1.79 -1.03 2.11 0.34
10299 || orf19.2882 || XUT1 || || Putative high-affinity, high-capacity xanthine-uric acid/H+ symporter; similar to A. nidulans UapA; member of the Nucleobase-Ascorbate Transporter/Nucleobase-Cation Symporter (NAT/NCS2) family; rat catheter biofilm induced || 1 -1.10 -0.85 -0.47 -0.86 0.52 1.47 -1.41 -1.49 -2.07 -0.26 -0.86 0.67 -1.76 -0.99 0.99 -0.19
10300 || orf19.7029 || || || Putative guanine deaminase; mutation confers hypersensitivity to toxic ergosterol analog; Spider biofilm induced || 1 -1.65 -1.67 -0.84 -0.34 0.96 2.70 -2.98 -2.18 -0.95 -0.79 -2.70 -0.04 -1.66 -2.40 2.54 -1.06
10301 || orf19.3664 || HSP31 || || Putative 30 kda heat shock protein; repressed during the mating process; rat catheter biofilm induced || 1 -1.34 -1.31 -0.01 0.10 -0.19 1.16 -1.89 -2.45 0.08 -1.14 -2.26 0.19 -1.10 -1.74 1.31 -0.49
10302 || orf19.3664 || HSP31 || || Putative 30 kda heat shock protein; repressed during the mating process; rat catheter biofilm induced || 1 -1.88 -1.53 -0.46 -0.58 -0.26 1.15 -2.07 -2.61 -0.46 -1.11 -2.06 0.45 -1.82 -1.46 1.30 -0.01
10303 || orf19.1115 || GUK1 || || Putative guanylate kinase; identified in extracts from biofilm and planktonic cells; protein level decrease in stationary phase cultures; Hap43p-induced gene || 1 -2.78 -2.68 -1.35 -0.79 0.63 0.87 -2.04 -1.59 -1.24 0.24 -0.55 -0.22 -2.67 -0.07 0.61 -0.79
10304 || orf19.4114 || FAA2-1 || || Predicted long chain fatty acid CoA ligase; upregulated upon phagocytosis; induced by nitric oxide independent of Yhb1 || 1 -0.98 -0.92 -0.38 -0.19 -0.18 0.08 -0.64 -0.51 -0.24 -0.05 -0.81 -0.30 -1.21 -0.09 0.14 -0.52
10305 || orf19.2951 || HOM6 || || Putative homoserine dehydrogenase; Gcn4-regulated; induced by amino acid starvation (3-ATtreatment); macrophage-induced protein; protein level decreases in stationary phase cultures; flow model biofilm repressed || 1 -1.16 -1.26 -0.68 -0.15 -0.14 0.13 -1.00 -0.86 -0.35 -0.54 -0.85 -0.25 -1.43 -0.47 0.75 -0.83
10306 || orf19.3827 || || || Ortholog(s) have metalloendopeptidase activity, role in misfolded or incompletely synthesized protein catabolic process and mitochondrial inner membrane localization || 1 -0.61 -0.70 -0.53 -0.61 0.28 0.38 -0.35 -0.57 -0.37 -0.79 -0.92 -0.75 -0.75 -0.19 0.39 -0.30
10307 || orf19.3827 || || || Ortholog(s) have metalloendopeptidase activity, role in misfolded or incompletely synthesized protein catabolic process and mitochondrial inner membrane localization || 1 -1.08 -1.07 -0.62 -0.67 0.20 0.55 -0.57 -0.84 -0.42 -0.74 -1.08 -0.63 -1.18 -0.12 0.24 -0.07
10308 || orf19.5447 || HGT19 || || Putative MFS glucose/myo-inositol transporter; 20 member family; 12 transmembrane segments, extended N terminus; expressed in rich medium; Hap43, phagocytosis, rat catheter, Spider and flow model biofilm induced || 1 -4.16 -4.42 -2.29 -2.37 1.27 2.52 -4.10 -3.51 -2.27 -1.52 -2.65 -0.45 -4.55 -2.72 1.72 -2.56
10309 || orf19.5447 || HGT19 || || Putative MFS glucose/myo-inositol transporter; 20 member family; 12 transmembrane segments, extended N terminus; expressed in rich medium; Hap43, phagocytosis, rat catheter, Spider and flow model biofilm induced || 1 -1.81 -1.99 -0.88 -0.84 0.81 1.83 -2.17 -2.25 -0.94 -1.22 -2.08 -0.88 -2.26 -1.90 1.53 -1.67
10310 || orf19.4886 || || || Putative adhesin-like protein; Hap43-repressed; rat catheter and Spider biofilm induced || 1 -3.75 -3.43 -1.83 -2.34 0.38 2.93 -3.94 -3.38 -2.20 -0.87 -4.70 -1.86 -3.76 -3.55 2.09 -2.53
10311 || orf19.4886 || || || Putative adhesin-like protein; Hap43-repressed; rat catheter and Spider biofilm induced || 1 -4.40 -4.02 -1.52 -2.02 0.14 2.86 -4.50 -4.04 -2.81 -2.44 -4.65 -1.76 -4.58 -2.52 2.14 -1.21
10312 || orf19.4886 || || || Putative adhesin-like protein; Hap43-repressed; rat catheter and Spider biofilm induced || 1 -4.54 -4.71 -3.15 -2.69 0.20 2.78 -4.87 -4.30 -2.55 -2.84 -4.86 -1.18 -5.00 -1.47 2.17 -3.49
10313 || orf19.4886 || || || Putative adhesin-like protein; Hap43-repressed; rat catheter and Spider biofilm induced || 1 -3.84 -4.35 -2.97 -3.35 0.27 3.14 -3.36 -3.40 -2.21 -2.33 -3.99 -1.71 -4.96 -2.97 2.27 -3.72
10314 || orf19.4886 || || || Putative adhesin-like protein; Hap43-repressed; rat catheter and Spider biofilm induced || 1 -4.26 -3.70 -3.19 -3.89 0.26 3.12 -2.95 -3.37 -1.74 -2.86 -4.31 -1.77 -4.57 2.37 -2.05
10315 || orf19.3527 || CYT1 || || Cytochrome c1; induced in high iron; alkaline repressed; possibly an essential gene, disruptants not obtained by UAU1 method; Hap43-repressed; Spider biofilm repressed || 1 -1.69 -1.72 -1.51 -1.51 0.67 2.00 -1.42 -1.47 -1.02 -1.13 -1.28 -0.37 -1.08 -1.74 1.48 -1.06
10316 || orf19.7254 || || || Ortholog(s) have role in mRNA metabolic process, mitochondrial translational initiation and extrinsic to membrane, mitochondrial inner membrane localization || 1 -0.78 -0.93 -0.81 -0.75 0.44 0.60 -0.41 -0.62 -0.66 -0.14 -0.32 -0.05 -0.27 -0.52 0.39 0.18
10317 || orf19.4820 || || || Ortholog(s) have mitochondrion localization || 1 -1.62 -1.70 -1.34 -1.65 0.61 0.76 -1.17 -1.38 -0.91 -0.16 -1.12 0.13 -0.98 -0.39 0.19 -0.30
10318 || orf19.3469 || || || S. cerevisiae ortholog Stb1 has a role in regulation of MBF-specific transcription at Start; induced in a cyr1 null mutant; Spider biofilm induced || 1 -2.04 -2.11 -1.35 -1.63 0.71 1.07 -1.34 -1.61 -0.58 -0.27 -0.91 -0.07 -0.71 -0.65 0.68 -1.01
10319 || orf19.4820 || || || Ortholog(s) have mitochondrion localization || 1 -1.83 -1.95 -1.37 -1.30 0.67 0.75 -1.09 -1.28 -0.55 -0.15 -1.16 -0.75 -1.03 -1.34 0.17 -0.89
10320 || orf19.4820 || || || Ortholog(s) have mitochondrion localization || 1 -1.60 -1.90 -1.40 -1.52 0.98 0.92 -0.91 -1.11 -0.56 -0.22 -1.03 -0.32 -0.98 -0.94 0.13 -0.76
10321 || orf19.4820 || || || Ortholog(s) have mitochondrion localization || 1 -1.30 -1.58 -1.45 -1.52 1.05 0.79 -0.84 -0.82 -0.68 -0.12 -0.80 -0.39 -0.58 -1.02 0.41 -0.65
10322 || orf19.4820 || || || Ortholog(s) have mitochondrion localization || 1 -1.35 -1.16 -1.02 -0.88 0.89 1.14 -1.00 -0.91 -0.65 -0.17 -1.13 -0.35 -1.02 -1.14 0.25 -0.36
10323 || orf19.3839 || SAP10 || || Secreted aspartyl protease; roles in adhesion, virulence (RHE model), cell surface integrity; distinct specificity from Sap9; at cell membrane and wall; GPI-anchored; induced in low iron; Tbf1-activated; Spider biofilm induced || 1 -1.90 -2.15 -1.55 -1.50 0.32 0.49 -0.66 -1.41 -0.40 -1.07 -0.67 0.31 -1.68 -0.99 0.36 -0.77
10324 || orf19.1725 || || || Putative adhesin-like protein || 1 -1.52 -1.25 -1.47 -1.86 0.72 0.47 -2.70 -2.38 -1.10 -1.13 -1.30 -0.75 -1.22 -0.94 0.45 -1.39
10325 || orf19.255 || ZCF1 || || Zn(II)2Cys6 transcription factor; transcript regulated during hypha formation; 5'-UTR intron; mutants show decreased colonization of mouse kidneys; flow model biofilm induced; Spider biofilm induced || 1 -1.61 -1.79 -0.32 -0.22 0.85 0.77 -1.80 -1.47 -0.78 -0.69 -0.75 0.05 -0.79 -0.36 0.79 -0.42
10326 || orf19.255 || ZCF1 || || Zn(II)2Cys6 transcription factor; transcript regulated during hypha formation; 5'-UTR intron; mutants show decreased colonization of mouse kidneys; flow model biofilm induced; Spider biofilm induced || 1 -2.02 -1.81 -0.74 -0.74 0.65 0.70 -1.91 -1.72 -1.29 -0.96 -1.04 -0.58 -0.79 -0.26 0.64 -0.80
10327 || orf19.2686 || || || Ortholog(s) have carboxypeptidase activity, role in nitrogen compound metabolic process, proteolysis involved in cellular protein catabolic process and fungal-type vacuole lumen localization || 1 -1.18 -1.29 -0.30 -0.40 0.37 0.76 -1.03 -1.37 -0.84 -1.06 -1.03 -0.12 -0.55 -0.44 0.59 -0.12
10328 || orf19.2686 || || || Ortholog(s) have carboxypeptidase activity, role in nitrogen compound metabolic process, proteolysis involved in cellular protein catabolic process and fungal-type vacuole lumen localization || 1 -1.43 -1.32 -0.09 -0.14 0.02 0.71 -0.95 -1.36 -0.57 -0.86 -1.04 -0.15 -0.65 -0.50 0.53 -0.17
10329 || orf19.7257 || MLH3 || || Ortholog(s) have role in meiotic mismatch repair, reciprocal meiotic recombination and MutLbeta complex localization || 1 -0.80 -0.72 -0.27 -0.45 0.22 0.41 -0.71 -0.64 -0.33 -0.35 -0.56 -0.14 -0.54 -0.28 0.41 0.11
10330 || orf19.5431 || || || Protein of unknown function; Hap43-repressed; Spider biofilm induced || 1 -3.41 -3.89 -2.02 -1.70 0.26 1.75 -2.52 -3.21 -2.70 -2.11 -1.98 -0.15 -1.95 -0.93 1.89 -0.38
10331 || orf19.5431 || || || Protein of unknown function; Hap43-repressed; Spider biofilm induced || 1 -4.25 -4.30 -2.59 -2.02 0.42 1.88 -2.39 -3.40 -2.36 -1.87 -1.82 0.19 -1.93 -0.37 2.26 -0.28
10332 || orf19.5380 || LYS144 || || Zn(II)2Cys6 transcription factor; has similarity to S. cerevisiae Lys14, involved in the regulation of lysine biosynthesis genes || 1 -0.96 -1.06 -0.47 -0.51 0.23 0.23 -0.58 -0.86 -0.48 -0.52 -0.32 0.52 -0.42 -0.11 0.32 0.03
10333 || orf19.6005 || HGT5 || || Putative glucose transporter of the major facilitator superfamily; the C. albicans glucose transporter family comprises 20 members; 12 probable membrane-spanning segments, extended N terminus; expressed in rich medium; Hap43p-repressed || 1 -1.25 -0.86 -0.72 -0.58 0.17 0.39 -0.94 -1.07 -0.17 -0.55 -0.50 0.29 -0.39 -0.34 0.17 -0.01
10334 || orf19.1816 || ALS3 || || Cell wall adhesin; epithelial adhesion, endothelial invasion; alleles vary in adhesiveness; immunoprotective in mice; binds SspB adhesin of S. gordonii in mixed biofilm; induced in/required for Spider biofilm; flow model biofilm repressed || 1 -1.53 -1.41 -1.33 -1.69 0.82 0.85 -2.00 -2.41 -1.25 -2.07 -0.40 -0.47 -0.89 -0.67 0.22 -0.36
10335 || orf19.5953 || || || C2H2 transcription factor; predicted regulator of ribosomal protein and biogenesis genes; possibly essential, disruptants not obtained by UAU1 method; rat catheter biofilm induced || 1 -0.93 -0.95 -0.50 -1.14 0.42 0.77 -1.08 -1.22 -0.67 -0.70 -0.47 -0.12 -0.57 -0.56 0.03 0.19
10336 || orf19.7400 || ALS7 || || ALS family protein; hypermutable contingency gene; growth-regulated, downregulated in biofilm; two variable repeat regions; expression in S. cerevisiae does not confer adhesiveness; ALS family includes adhesins, cell-surface glycoproteins || 1 -1.46 -1.28 -0.91 -0.80 0.37 0.51 -1.06 -1.11 -0.77 -1.05 -0.69 -0.38 -0.68 -0.38 -0.24 0.10
10337 || orf19.4534 || || || Putative UBX-domain (ubiquitin-regulatory domain) protein; macrophage-downregulated gene || 1 -1.49 -1.48 -0.62 -0.54 0.36 0.78 -0.94 -1.13 -0.92 -0.88 -0.36 -0.21 -0.26 -0.43 0.19 0.05
10338 || orf19.3302 || || || Putative type-1 protein phosphatase targeting subunit; transcript repressed by yeast-hyphal switch; transcript induced by Mnl1p under weak acid stress; flow model biofilm induced || 1 -1.42 -1.48 -0.88 -0.70 0.58 0.90 -1.01 -1.42 -0.80 -1.66 -0.34 -0.33 -0.42 -0.45 0.42 0.33
10339 || orf19.3302 || || || Putative type-1 protein phosphatase targeting subunit; transcript repressed by yeast-hyphal switch; transcript induced by Mnl1p under weak acid stress; flow model biofilm induced || 1 -1.57 -1.54 -0.94 -0.78 0.57 0.73 -1.03 -1.51 -0.94 -1.68 -0.40 -0.27 -0.61 -0.21 0.18 0.84
10340 || orf19.6680 || FGR27 || || Zn(II)2Cys6 transcription factor; transposon mutation affects filamentous growth; required for yeast cell adherence to silicone substrate; Spider biofilm induced || 1 -2.00 -2.07 -1.17 -1.42 0.13 0.84 -0.62 -0.81 -0.76 -1.23 -0.26 0.30 -0.03 0.28 0.10 0.03
10341 || orf19.6680 || FGR27 || || Zn(II)2Cys6 transcription factor; transposon mutation affects filamentous growth; required for yeast cell adherence to silicone substrate; Spider biofilm induced || 1 -1.70 -1.98 -0.98 -1.24 0.14 0.52 -0.50 -0.75 -0.92 -1.28 -0.32 0.13 0.00 -0.08 0.17 -0.00
10342 || orf19.3508 || || || Putative protein of unknown function; stationary phase enriched protein || 1 -1.65 -1.86 -1.14 -1.21 0.61 0.73 -1.04 -1.07 -0.73 -1.09 -0.43 -0.17 -0.60 -0.08 0.37 0.10
10343 || orf19.4534 || || || Putative UBX-domain (ubiquitin-regulatory domain) protein; macrophage-downregulated gene || 1 -1.99 -1.70 -1.40 -1.13 0.38 0.66 -0.90 -0.98 -0.91 -0.73 -0.33 -0.03 -0.38 0.21 0.79 0.17
10344 || orf19.418 || KOG1 || || Putative TORC1 subunit; heterozygous null mutant displays sensitivity to rapamycin; likely to be essential for growth, based on an insertional mutagenesis strategy || 1 -1.37 -1.01 -1.08 -0.75 0.43 0.13 -0.34 -0.55 -0.26 -0.58 -0.12 0.04 -0.33 -0.24 0.52 0.13
10345 || orf19.4706 || || || Protein of unknown function; induced in cyr1 or ras1 mutant; induced by fluconazole, by alpha pheromone in SpiderM medium and during oralpharyngeal candidasis; Spider biofilm induced || 1 -1.84 -2.00 -1.68 -0.98 0.32 0.46 -0.05 -1.16 -0.45 -0.31 -0.88 -0.28 -0.75 0.63 1.23 -0.04
10346 || orf19.4706 || || || Protein of unknown function; induced in cyr1 or ras1 mutant; induced by fluconazole, by alpha pheromone in SpiderM medium and during oralpharyngeal candidasis; Spider biofilm induced || 1 -2.10 -2.17 -1.64 -1.32 0.08 0.28 -0.47 -1.75 -0.86 -0.51 -1.30 -0.25 -1.10 1.01 1.26 0.22
10347 || orf19.4706 || || || Protein of unknown function; induced in cyr1 or ras1 mutant; induced by fluconazole, by alpha pheromone in SpiderM medium and during oralpharyngeal candidasis; Spider biofilm induced || 1 -1.93 -2.20 -0.91 -0.94 -0.06 0.14 -0.79 -1.50 -0.56 -0.60 -1.27 -0.59 -0.95 0.36 0.92 -0.56
10348 || orf19.2131 || || || Ortholog(s) have ubiquitin-protein ligase activity and role in protein ubiquitination, ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway || 1 -1.00 -0.91 -0.73 -0.65 -0.10 0.24 -0.57 -0.63 -0.26 -0.52 -0.34 -0.37 -0.63 0.02 0.51 0.13
10349 || orf19.4706 || || || Protein of unknown function; induced in cyr1 or ras1 mutant; induced by fluconazole, by alpha pheromone in SpiderM medium and during oralpharyngeal candidasis; Spider biofilm induced || 1 -1.50 -1.33 -1.67 -1.19 0.01 0.12 -0.80 -1.80 -1.14 -0.80 -1.20 -0.79 -0.62 0.26 0.56 -0.22
10350 || orf19.6928 || SAP9 || || Secreted aspartyl protease; roles in adhesion, cell surface integrity; induced by antifungal drugs, stationary phase, or in white-phase cells; farnesol-downregulated in biofilm; autocatalytic processing; GPI-anchor; Spider biofilm induced || 1 -1.37 -1.41 -0.94 -0.80 0.02 0.14 -0.31 -1.44 -1.07 -1.32 -0.67 -0.05 -0.73 0.25 0.76 0.31
10351 || orf19.7400 || ALS7 || || ALS family protein; hypermutable contingency gene; growth-regulated, downregulated in biofilm; two variable repeat regions; expression in S. cerevisiae does not confer adhesiveness; ALS family includes adhesins, cell-surface glycoproteins || 1 -1.18 -1.14 0.06 -0.27 0.49 0.77 -0.77 -0.84 -0.24 -0.84 -0.51 -0.21 -0.48 -0.24 0.10 0.20
10352 || orf19.2073 || || || Protein with a multidrug and toxin extrusion protein domain; induced by Mnl1 under weak acid stress || 1 -0.91 -0.89 -0.13 -0.40 0.27 0.56 -0.82 -0.91 0.12 -0.57 -0.60 -0.23 -0.68 -0.56 -0.14 -0.07
10353 || orf19.1054 || || || Ortholog(s) have structural constituent of nuclear pore activity || 1 -0.93 -1.00 -0.48 -0.15 -0.03 0.34 -1.08 -0.67 -0.76 -0.35 0.32 0.45 -0.04 -0.76 0.28 -0.09
10354 || orf19.3073 || || || Protein of unknown function || 1 -1.50 -1.64 -0.56 -0.28 0.11 0.90 -1.65 -1.04 -1.42 -0.92 0.43 0.44 -1.25 -2.06 0.99 0.04
10355 || orf19.3073 || || || Protein of unknown function || 1 -1.79 -1.75 -0.62 -0.22 0.10 0.88 -1.56 -1.04 -1.18 -0.54 0.45 0.70 -1.42 -1.56 1.06 0.10
10356 || orf19.1632 || || || Ortholog(s) have cytosol, nucleus localization || 1 -0.31 -0.44 -0.96 -0.37 0.33 0.91 -0.47 -0.58 -0.54 -0.54 0.37 0.70 -0.63 -0.51 0.47 -0.03
10357 || orf19.1191 || || || Ortholog(s) have ubiquitin-protein ligase activity and role in ER-associated ubiquitin-dependent protein catabolic process || 1 -0.56 -0.52 -0.52 -0.42 0.31 0.01 -0.30 -0.35 -0.32 -0.34 0.11 -0.07 -0.38 -0.38 0.38 0.30
10358 || orf19.424 || TRP99 || || Putative thioredoxin peroxidase/alkyl hydroperoxide reductase; induced in low iron; regulated by Gcn4; induced in response to amino acid starvation (3-AT treatment) || 1 -0.67 -0.88 -0.54 -0.49 -0.09 0.40 -0.65 -0.44 -0.77 -0.28 0.43 0.42 -1.28 -0.81 0.14 0.16
10359 || orf19.424 || TRP99 || || Putative thioredoxin peroxidase/alkyl hydroperoxide reductase; induced in low iron; regulated by Gcn4; induced in response to amino acid starvation (3-AT treatment) || 1 -0.72 -0.86 -0.96 -0.66 -0.01 0.45 -0.75 -0.45 -0.89 -0.44 0.44 0.55 -1.35 -0.73 0.27 0.00
10360 || orf19.3482 || || || Ortholog(s) have NAD+ diphosphatase activity, role in NADH metabolic process and cytosol, nucleus, peroxisome localization || 1 -0.39 -0.40 -0.39 -0.35 0.19 0.32 -0.53 -0.25 -0.27 -0.09 0.17 0.50 -0.80 -0.39 0.35 0.29
10361 || orf19.5052 || || || Ortholog of S. cerevisiae : YFR045W, C. glabrata CBS138 : CAGL0C02013g, C. dubliniensis CD36 : Cd36_07340, C. parapsilosis CDC317 : CPAR2_208340 and Candida tenuis NRRL Y-1498 : CANTEDRAFT_116470 || 1 -0.85 -0.96 -0.51 -0.85 0.08 0.56 -0.49 -0.76 -0.51 -0.05 0.23 0.87 -1.10 -0.41 0.19 0.57
10362 || orf19.4756 || || || Ortholog of S. cerevisiae : YTP1, C. dubliniensis CD36 : Cd36_08490, C. parapsilosis CDC317 : CPAR2_801590, Candida tenuis NRRL Y-1498 : CANTEDRAFT_109732 and Debaryomyces hansenii CBS767 : DEHA2C10384g || 1 -1.50 -1.34 -1.06 -0.56 -0.22 0.60 -1.09 -0.93 -0.73 -0.20 -0.00 0.78 -1.56 -0.81 0.73 0.72
10363 || orf19.2726 || || || Putative plasma membrane protein; Plc1-regulated; Spider biofilm induced || 1 -1.38 -1.54 -1.79 -0.95 -0.20 0.67 -0.97 -1.15 -1.46 0.14 0.33 0.92 -1.30 -0.60 0.90 0.78
10364 || orf19.5621 || || || Putative protein of unknown function; mutation confers hypersensitivity to amphotericin B; overlaps orf19.5621 || 1 -0.72 -0.83 -0.97 -0.81 0.39 0.34 -1.01 -0.83 -0.47 -0.06 0.32 0.81 -0.73 -0.16 0.72 0.56
10365 || orf19.851 || || || Protein of unknown function; repressed by Rim101; negatively modulates intracellular ATP levels during the development of azole resistance; induced by Ca(2+) in a calcineurin-dependent manner; Spider biofilm induced || 1 -1.38 -1.67 -1.90 -2.03 -0.10 0.56 -1.03 -1.65 -1.59 -1.02 0.85 1.61 -1.28 -0.57 1.98 1.05
10366 || orf19.3071 || MIH1 || || Putative protein phosphatase of the PTP family (tyrosine-specific); ortholog of S. cerevisiae Mih1; mRNA binds She3 || 1 -2.30 -2.37 -2.29 -2.19 0.24 0.19 -2.08 -1.88 -2.06 -1.72 1.00 1.41 -1.40 -0.84 1.74 1.33
10367 || orf19.4147 || GLR1 || || Glutathione reductase; upregulated by human neutrophils; oxidative stress-induced regulation via Cap1p; overexpression correlates with multidrug resistance in a cap1 mutant, farnesol induced; stationary phase enriched protein || 1 -1.08 -0.94 -1.14 -0.75 0.23 0.53 -0.40 -0.69 -0.74 -0.55 0.53 0.61 -1.12 -0.75 1.07 0.25
10368 || orf19.6515 || HSP90 || || Essential chaperone, regulates several signal transduction pathways and temperature-induced morphogenesis; activated by heat shock, stress; localizes to surface of hyphae, not yeast cells; mediates echinocandin and biofilm azole resistance || 1 -0.60 -0.73 -1.11 0.08 0.37 -0.21 -0.28 -0.11 -0.24 0.44 0.28 -0.85 -0.05 0.49 0.21
10369 || orf19.6515 || HSP90 || || Essential chaperone, regulates several signal transduction pathways and temperature-induced morphogenesis; activated by heat shock, stress; localizes to surface of hyphae, not yeast cells; mediates echinocandin and biofilm azole resistance || 1 -0.46 -0.46 -0.69 -0.70 0.26 0.28 -0.09 -0.01 -0.17 -0.23 0.32 0.47 -0.49 -0.26 0.35 0.29
10370 || orf19.6058 || GLO1 || || Putative monomeric glyoxalase I; oxidative stress-induced via Cap1; flow model and rat catheter biofilm repressed || 1 -1.57 -1.50 -1.67 -1.57 0.58 0.47 -0.22 -0.35 -0.41 -0.64 1.20 0.91 -1.29 -0.37 0.67 0.54
10371 || orf19.349 || || || Ortholog(s) have role in aerobic respiration, mRNA metabolic process and mitochondrial outer membrane localization || 1 -0.97 -1.03 -1.26 -1.37 0.57 0.63 -0.63 -0.42 -0.15 -0.52 0.60 0.92 -1.01 0.03 0.30 0.59
10372 || orf19.2722 || CGR1 || || Negative regulator of yeast-form growth; HSP70 family member; induced by growth cessation at yeast-hyphal transition or in planktonic growth; physically interacts with Msi3p; similar to rat anti-aging gene, SMP30, stationary phase enriched || 1 -1.16 -1.26 -1.12 -1.47 0.54 0.89 -0.94 -0.41 -0.41 -0.47 0.31 1.03 -0.82 -0.70 0.75 0.80
10373 || orf19.1676 || || || Predicted potassium ion transporter; Spider biofilm induced || 1 -0.85 -0.79 -1.19 -0.98 0.66 0.96 -0.54 -0.71 -0.36 -0.35 0.56 0.86 -0.84 -0.68 0.66 0.91
10374 || orf19.53 || || || Ortholog(s) have role in generation of catalytic spliceosome for first transesterification step, mRNA cis splicing, via spliceosome and commitment complex, cytosol localization || 1 -1.22 -1.01 -1.23 -1.44 0.93 0.69 -0.61 -0.66 -0.99 -0.69 0.68 0.87 -0.48 -1.21 0.59 1.30
10375 || orf19.4250 || || || Ortholog of C. dubliniensis CD36 : Cd36_52200, C. parapsilosis CDC317 : CPAR2_502480, Candida tenuis NRRL Y-1498 : CANTEDRAFT_115972 and Debaryomyces hansenii CBS767 : DEHA2G19976g || 1 -1.63 -1.88 -2.75 -2.27 0.87 0.95 -0.72 -0.26 -1.59 -0.41 1.62 1.24 -1.08 -1.47 1.09 1.11
10376 || orf19.5052 || || || Ortholog of S. cerevisiae : YFR045W, C. glabrata CBS138 : CAGL0C02013g, C. dubliniensis CD36 : Cd36_07340, C. parapsilosis CDC317 : CPAR2_208340 and Candida tenuis NRRL Y-1498 : CANTEDRAFT_116470 || 1 -0.99 -1.12 -0.84 -1.01 -0.07 0.25 -0.38 -0.39 -0.51 -0.14 0.29 0.61 -0.91 -0.53 0.11 0.23
10377 || orf19.6189 || || || Chalcone related protein family; flow model biofilm induced || 1 -1.41 -1.36 -1.55 -1.53 -0.01 0.09 -0.69 -0.56 -0.91 -0.38 0.74 0.74 -1.50 -0.87 0.34 0.95
10378 || orf19.2969 || RAD16 || || Ortholog of S. cerevisiae Rad16; a protein that recognizes and binds damaged DNA; flucytosine induced; rat catheter and Spider biofilm induced || 1 -1.41 -1.35 -1.82 -1.62 0.26 0.69 -0.86 -1.08 -0.84 -0.98 0.67 0.67 -1.74 -0.99 0.31 0.77
10379 || orf19.5799 || || || Ortholog(s) have cytoplasm localization || 1 -0.76 -0.80 -1.25 -0.97 0.08 0.22 -0.83 -0.62 -0.35 -0.41 0.34 0.14 -1.01 -0.87 0.21 0.72
10380 || orf19.4195.1 || FCA1 || || Cytosine deaminase; enzyme of pyrimidine salvage; functional homolog of S. cerevisiae Fcy1p; mutation is associated with resistance to flucytosine (5-FC) in a clinical isolate; hyphal downregulated; gene has intron || 1 -1.93 -1.63 -3.20 -1.70 0.88 1.46 -1.65 -1.44 -1.80 -1.75 1.97 1.23 -1.83 -2.97 0.58 1.43
10381 || orf19.3663.1 || || || Predicted plasma membrane protein; gene has intron || 1 -1.32 -1.42 -1.18 -0.54 0.37 0.49 -0.83 -0.51 -0.47 -0.84 0.42 0.94 -0.91 -0.80 0.27 -0.12
10382 || orf19.1676 || || || Predicted potassium ion transporter; Spider biofilm induced || 1 -1.15 -0.80 -1.07 -1.11 0.94 1.06 -0.26 -0.43 -0.20 -0.15 1.15 1.09 -0.88 -0.95 1.22 0.74
10383 || orf19.4380.1 || || || Ortholog(s) have role in mitochondrial genome maintenance and integral to mitochondrial inner membrane localization || 1 -1.24 -1.05 -0.68 -0.92 0.66 1.05 -0.45 -0.72 -0.50 -0.87 0.48 0.64 -0.84 -0.72 1.14 0.84
10384 || orf19.4380.1 || || || Ortholog(s) have role in mitochondrial genome maintenance and integral to mitochondrial inner membrane localization || 1 -1.08 -1.03 -1.04 -0.96 0.85 1.12 -0.24 -0.65 -0.35 -0.73 0.62 0.82 -0.74 -0.81 1.37 0.70
10385 || orf19.4379 || PRP13 || || Putative integral inner mitochondrial membrane protein with similarity to exonucleases || 1 -0.89 -0.96 -0.86 -0.88 0.86 1.20 -0.40 -0.70 -0.47 -0.82 0.58 0.77 -0.76 -0.52 1.28 0.72
10386 || orf19.4379 || PRP13 || || Putative integral inner mitochondrial membrane protein with similarity to exonucleases || 1 -0.98 -1.09 -0.94 -1.19 0.75 1.17 -0.30 -0.70 -0.33 -0.72 0.56 0.85 -0.92 -0.51 1.44 0.90
10387 || orf19.6245 || || || Protein of unknown function; regulated by osmotic stress via Hog1 and oxidative stress (Hog1- and Cap1-independent); induced by alpha pheromone in SpiderM medium; Spider biofilm induced || 1 -0.82 -0.75 -0.86 -0.93 0.90 0.93 -0.49 -0.63 -0.34 -1.00 0.94 0.89 -0.71 -0.75 1.33 0.20
10388 || orf19.7311 || || || Protein of unknown function; Spider biofilm induced || 1 -0.83 -1.51 -0.88 -1.30 1.41 2.43 -0.60 -0.82 -0.64 -1.12 0.95 1.52 -0.74 -0.56 2.01 1.05
10389 || orf19.2063 || || || Ortholog of C. parapsilosis CDC317 : CPAR2_213140, C. dubliniensis CD36 : Cd36_15600, Lodderomyces elongisporus NRLL YB-4239 : LELG_01226 and Debaryomyces hansenii CBS767 : DEHA2B02442g || 1 -1.06 -0.93 -0.79 -1.21 1.08 1.76 -1.20 -0.98 -1.00 -1.34 0.57 1.15 -0.28 -0.66 1.00 1.43
10390 || orf19.7570 || UGA3 || || Zn(II)2Cys6 transcription factor; required for utilization of gamma-aminobutyrate (GABA) as a nitrogen source; mutants display decreased CFU in mouse kidneys; Spider biofilm induced || 1 -0.98 -1.08 -0.58 -0.75 0.91 1.33 -0.84 -0.85 -0.48 -1.37 0.39 0.87 -0.47 -1.11 1.25 0.85
10391 || orf19.6116 || GLK4 || || Putative glucokinase; decreased expression in hyphae compared to yeast-form cells || 1 -1.30 -1.37 -1.02 -1.47 1.00 1.45 -1.10 -1.50 -0.92 -2.04 0.36 0.60 -0.83 -0.93 1.35 0.94
10392 || orf19.1887 || || || Ortholog(s) have sterol esterase activity, role in sterol metabolic process and integral to membrane, lipid particle localization || 1 -1.05 -0.99 -0.67 -0.97 0.46 0.96 -0.99 -0.77 -0.83 -1.33 0.26 0.23 -0.44 -0.98 0.81 0.76
10393 || orf19.6951 || || || Ortholog(s) have sphinganine-1-phosphate aldolase activity and role in calcium-mediated signaling, cellular response to starvation, sphingolipid metabolic process || 1 -1.14 -1.32 -0.89 -1.12 0.51 1.17 -1.00 -1.02 -0.82 -0.78 0.34 0.47 -0.30 -0.93 1.20 0.64
10394 || orf19.6951 || || || Ortholog(s) have sphinganine-1-phosphate aldolase activity and role in calcium-mediated signaling, cellular response to starvation, sphingolipid metabolic process || 1 -1.26 -1.31 -0.87 -1.08 0.25 0.96 -0.83 -1.13 -1.03 -1.06 0.34 0.37 -0.39 -1.06 1.24 0.50
10395 || orf19.6951 || || || Ortholog(s) have sphinganine-1-phosphate aldolase activity and role in calcium-mediated signaling, cellular response to starvation, sphingolipid metabolic process || 1 -1.21 -1.22 -0.95 -1.00 0.05 1.08 -0.93 -0.96 -0.88 -0.98 0.31 0.47 -0.68 -1.04 1.22 0.59
10396 || orf19.6951 || || || Ortholog(s) have sphinganine-1-phosphate aldolase activity and role in calcium-mediated signaling, cellular response to starvation, sphingolipid metabolic process || 1 -1.27 -1.29 -0.96 -1.16 0.08 1.10 -1.08 -1.01 -0.85 -0.82 0.16 0.52 -0.60 -0.67 1.10 0.46
10397 || orf19.6951 || || || Ortholog(s) have sphinganine-1-phosphate aldolase activity and role in calcium-mediated signaling, cellular response to starvation, sphingolipid metabolic process || 1 -1.40 -1.58 -0.59 -1.02 0.06 1.07 -1.05 -1.16 -1.06 -0.91 0.21 0.53 -0.78 -0.58 1.15 0.51
10398 || orf19.3047 || || || Protein kinase-related protein, required for normal sensitivity to caspofungin || 1 -0.97 -1.13 -0.72 -0.73 0.36 0.92 -0.71 -0.69 -0.39 -0.69 0.08 0.63 -0.69 -0.26 0.86 0.67
10399 || orf19.2050 || || || Ortholog(s) have sterol esterase activity, role in cellular lipid metabolic process, sterol metabolic process and fungal-type vacuole, integral to membrane, lipid particle localization || 1 -1.38 -1.28 -0.95 -1.07 1.01 1.40 -0.82 -1.01 -0.71 -0.90 0.12 0.31 -0.84 -0.13 1.32 0.93
10400 || orf19.1887 || || || Ortholog(s) have sterol esterase activity, role in sterol metabolic process and integral to membrane, lipid particle localization || 1 -1.86 -2.04 -2.05 -2.18 0.89 1.47 -1.61 -1.40 -1.66 -1.51 0.92 0.88 -0.20 -1.17 1.06 1.15
10401 || orf19.7311 || || || Protein of unknown function; Spider biofilm induced || 1 -0.98 -0.90 -0.99 -2.09 0.86 1.80 -0.58 -0.47 -0.95 -1.72 0.89 1.02 -0.48 -0.57 1.23 0.45
10402 || orf19.4317 || GRE3 || || Putative D-xylose reductase; antigenic in murine systemic infection; soluble protein in hyphae; induced by farnesol, macrophage interaction and by Mnl1 under weak acid stress; stationary-phase enriched protein; Spider biofilm induced || 1 -0.71 -0.60 -0.66 -1.01 0.58 0.98 -0.34 -0.87 -1.05 -1.04 -0.04 0.48 -0.83 -0.29 0.71 0.18
10403 || orf19.4317 || GRE3 || || Putative D-xylose reductase; antigenic in murine systemic infection; soluble protein in hyphae; induced by farnesol, macrophage interaction and by Mnl1 under weak acid stress; stationary-phase enriched protein; Spider biofilm induced || 1 -0.61 -0.62 -0.52 -0.64 0.46 1.20 -0.27 -0.75 -0.96 -1.18 -0.07 0.50 -0.78 -0.45 0.67 0.35
10404 || orf19.4317 || GRE3 || || Putative D-xylose reductase; antigenic in murine systemic infection; soluble protein in hyphae; induced by farnesol, macrophage interaction and by Mnl1 under weak acid stress; stationary-phase enriched protein; Spider biofilm induced || 1 -0.68 -0.51 -0.33 -0.56 0.56 1.14 -0.21 -0.70 -0.76 -1.09 0.05 0.70 -0.67 -0.17 0.85 0.54
10405 || orf19.7436 || AAF1 || || Possible regulatory protein; possible adhesin-like; Glu-rich domain; production in S. cerevisiae increases endothelial cell adherence and flocculence; flow model biofilm, alkaline or caspofungin induced || 1 -1.23 -1.24 -1.36 -1.22 1.90 2.11 -0.50 -1.66 -1.49 -1.92 0.52 0.71 0.11 -1.10 1.44 0.95
10406 || orf19.6874 || || || Putative helix-loop-helix (HLH) transcription factor with a role in filamentous growth || 1 -1.04 -1.01 -0.84 -0.92 0.98 1.32 -0.29 -0.58 -1.30 -1.28 0.67 0.10 -0.17 -0.91 0.55 0.82
10407 || orf19.6770 || || || protein with ENTH Epsin domain, N-terminal; Spider biofilm repressed || 1 -1.09 -1.05 -1.27 -1.09 1.14 1.67 -0.20 -0.98 -1.76 -1.34 1.18 0.53 -0.47 -0.97 0.71 1.08
10408 || orf19.6770 || || || protein with ENTH Epsin domain, N-terminal; Spider biofilm repressed || 1 -1.57 -1.43 -1.86 -1.33 1.22 1.69 -0.28 -1.20 -2.55 -1.33 1.23 0.26 -0.56 -1.10 0.70 1.05
10409 || orf19.6770 || || || protein with ENTH Epsin domain, N-terminal; Spider biofilm repressed || 1 -1.29 -1.47 -1.99 -1.63 1.63 1.59 -0.22 -1.24 -2.70 -1.61 1.45 0.20 -0.55 -1.32 0.81 0.85
10410 || orf19.6770 || || || protein with ENTH Epsin domain, N-terminal; Spider biofilm repressed || 1 -1.71 -1.74 -1.88 -1.56 0.95 1.38 -0.62 -1.39 -2.13 -1.55 0.92 0.10 -0.80 -1.24 0.55 1.00
10411 || orf19.5224 || PKH2 || || Putative serine/threonine protein kinase; predicted role in sphingolipid-mediated signaling pathway that controls endocytosis; mRNA binds She3 and is localized to hyphal tips || 1 -0.22 -0.31 -0.89 -0.74 0.46 0.33 -0.32 -0.56 -0.43 -0.95 0.27 0.06 -0.41 -0.62 0.63 0.38
10412 || orf19.5224 || PKH2 || || Putative serine/threonine protein kinase; predicted role in sphingolipid-mediated signaling pathway that controls endocytosis; mRNA binds She3 and is localized to hyphal tips || 1 -0.25 -0.39 -1.00 -0.71 0.41 0.39 -0.15 -0.59 -0.83 -0.95 0.37 0.50 -0.37 -0.18 0.76 0.54
10413 || orf19.1604 || || || Predicted Gal4-like DNA-binding transcription factor; Spider biofilm induced || 1 -0.51 -1.28 -1.07 -1.01 0.51 0.65 -0.28 -1.08 -1.03 -1.45 0.92 0.98 0.37 -0.69 1.03 1.36
10414 || orf19.7374 || CTA4 || || Zn(II)2Cys6 transcription factor; induced by nitric oxide; induced by Mnl1 under weak acid stress; repressed upon adherence to polystyrene; Hap43-repressed; Spider biofilm induced || 1 -0.45 -0.55 -1.35 -1.39 0.62 1.03 -0.27 -1.13 -1.26 -1.48 0.91 0.86 -0.45 -0.67 0.65 1.64
10415 || orf19.7374 || CTA4 || || Zn(II)2Cys6 transcription factor; induced by nitric oxide; induced by Mnl1 under weak acid stress; repressed upon adherence to polystyrene; Hap43-repressed; Spider biofilm induced || 1 -0.53 -0.80 -1.15 -1.56 0.52 0.81 -0.19 -1.49 -0.80 -1.54 0.81 0.44 -0.31 -0.62 0.47 1.87
10416 || orf19.6214 || ATC1 || || Cell wall acid trehalase; catalyzes hydrolysis of the disaccharide trehalose; similar to S. cerevisiae vacuolar acid trehalase (Ath1p); Hap43p-repressed gene || 1 -0.82 -0.49 -0.69 -0.55 0.14 0.49 -0.24 -0.46 -0.21 -1.34 0.15 -0.07 -0.06 -1.12 0.27 0.30
10417 || orf19.6214 || ATC1 || || Cell wall acid trehalase; catalyzes hydrolysis of the disaccharide trehalose; similar to S. cerevisiae vacuolar acid trehalase (Ath1p); Hap43p-repressed gene || 1 -0.75 -0.51 -0.58 -0.61 -0.16 0.39 -0.58 -0.75 -0.45 -1.38 0.01 0.50 -0.41 -1.04 0.32 0.48
10418 || orf19.5587 || || || Protein of unknown function; transcript is upregulated in clinical isolates from HIV+ patients with oral candidiasis || 1 -0.45 -0.50 -0.60 -0.90 0.14 0.25 -0.57 -0.99 -0.29 -1.47 0.24 0.38 -0.47 -1.44 0.71 0.11
10419 || orf19.2248 || ARE2 || || Acyl CoA:sterol acyltransferase; uses cholesterol and oleoyl-CoA substrates; protoberberine derivative drug inhibits enzyme activity; ketoconazole-induced; Hap43-repressed; flow model biofilm induced; Spider biofilm induced || 1 -0.33 -0.46 -0.21 -0.50 0.05 0.98 -0.70 -1.08 -0.38 -1.43 -0.17 -0.21 -0.91 -0.95 -0.28 0.29
10420 || orf19.736 || SRB8 || || Putative RNA polymerase II mediator complex subunit; early-stage flow model biofilm induced || 1 -0.02 -0.05 -0.10 -0.30 0.02 0.28 -0.33 -0.33 -0.31 -0.50 -0.22 -0.05 -0.53 -0.37 0.03 0.11
10421 || orf19.3441 || FRP6 || || Putative ammonia transport protein; regulated by Nrg1 and Tup1; regulated by Ssn6; induced by human neutrophils || 1 -1.44 -1.36 -1.28 -2.26 1.14 1.77 -2.09 -2.12 -1.77 -2.18 -0.69 -0.15 -1.92 -2.14 0.08 0.47
10422 || orf19.3441 || FRP6 || || Putative ammonia transport protein; regulated by Nrg1 and Tup1; regulated by Ssn6; induced by human neutrophils || 1 -1.62 -1.78 -1.33 -2.69 1.22 1.81 -2.39 -2.17 -2.04 -2.42 -0.42 -0.29 -2.34 -2.77 -0.30 0.65
10423 || orf19.3441 || FRP6 || || Putative ammonia transport protein; regulated by Nrg1 and Tup1; regulated by Ssn6; induced by human neutrophils || 1 -1.35 -1.66 -0.67 -2.33 1.55 1.84 -2.89 -2.15 -1.85 -1.86 -0.75 -0.20 -2.50 -2.68 -0.39 0.57
10424 || orf19.5205 || || || Protein of unknown function; Hap43-repressed gene || 1 -1.03 -0.96 -0.78 -1.47 0.93 0.95 -1.88 -2.03 -0.82 -1.71 -1.26 -0.40 -2.13 -1.76 -0.88 0.59
10425 || orf19.5205 || || || Protein of unknown function; Hap43-repressed gene || 1 -0.94 -0.89 -0.63 -1.93 1.00 1.23 -1.65 -2.01 -0.61 -1.55 -1.08 -0.28 -1.88 -1.45 -0.81 0.53
10426 || orf19.5205 || || || Protein of unknown function; Hap43-repressed gene || 1 -1.09 -0.95 -0.68 -1.46 1.01 1.13 -1.54 -1.72 -0.54 -1.81 -0.95 0.03 -2.14 -1.22 -0.69 0.46
10427 || orf19.5205 || || || Protein of unknown function; Hap43-repressed gene || 1 -1.26 -1.09 -1.48 -1.94 1.05 1.02 -2.02 -2.06 -0.65 -1.81 -1.08 -0.18 -2.42 -1.28 -0.79 0.58
10428 || orf19.7086 || || || Ortholog(s) have protein transporter activity, role in transcription factor import into nucleus and cytosol, nuclear envelope localization || 1 -0.53 -0.67 -0.57 -0.80 0.52 0.57 -0.54 -0.74 -0.15 -0.47 -0.14 -0.21 -0.47 -0.47 0.10 0.41
10429 || orf19.4362 || || || Ortholog(s) have role in protein targeting to mitochondrion and mitochondrial outer membrane localization || 1 -0.26 -0.52 -0.50 -0.53 0.23 0.35 -0.61 -0.63 -0.69 -0.18 -0.13 -0.10 -0.55 -0.56 0.60 0.11
10430 || orf19.5474 || || || Protein of unknown function; induced by Mnl1 under weak acid stress; transcript detected on high-resolution tiling arrays; Spider biofilm repressed || 1 -1.77 -1.68 -1.21 -0.86 -1.12 0.67 -1.42 -1.04 -1.52 -1.11 1.13 1.16 -1.27 -1.91 1.91 1.27
10431 || orf19.5469 || || || Protein with a predicted DEAD-like DNA/RNA helicase domain; shows colony morphology-related gene regulation by Ssn6; overlaps orf19.5472; Spider biofilm repressed || 1 -1.48 -1.66 -0.83 -0.68 -0.53 0.72 -1.57 -1.44 -1.41 -1.17 0.60 0.83 -1.21 -1.73 1.35 1.00
10432 || orf19.5469 || || || Protein with a predicted DEAD-like DNA/RNA helicase domain; shows colony morphology-related gene regulation by Ssn6; overlaps orf19.5472; Spider biofilm repressed || 1 -1.91 -1.91 -1.04 -1.07 -0.61 0.64 -1.72 -1.43 -1.58 -1.26 0.35 0.71 -1.34 -1.84 1.12 0.93
10433 || orf19.3007.2 || || || Ortholog of C. dubliniensis CD36 : Cd36_02950, C. parapsilosis CDC317 : CPAR2_108520, Candida tenuis NRRL Y-1498 : CANTEDRAFT_100285 and Debaryomyces hansenii CBS767 : DEHA2G15774g || 1 -1.73 -2.00 -1.64 -1.43 0.17 0.72 -2.16 -2.38 -2.14 -2.22 0.73 1.48 -1.59 -2.21 1.19 0.31
10434 || orf19.3007.2 || || || Ortholog of C. dubliniensis CD36 : Cd36_02950, C. parapsilosis CDC317 : CPAR2_108520, Candida tenuis NRRL Y-1498 : CANTEDRAFT_100285 and Debaryomyces hansenii CBS767 : DEHA2G15774g || 1 -1.81 -2.06 -1.36 -1.49 -0.02 0.55 -2.10 -2.31 -1.83 -2.02 0.79 1.51 -1.68 -2.12 1.16 0.49
10435 || orf19.1564 || || || Plasma membrane-localized protein of unknown function || 1 -1.12 -1.25 -0.65 -0.60 -0.52 0.22 -1.66 -1.63 -1.18 -1.00 0.35 1.05 -1.53 -1.25 0.86 0.58
10436 || orf19.24 || RTA2 || || Flippase; sphingolipid long chain base release; mediates calcineurin-dependent resistance to azoles; stress-associate; Plc1, Ca2+, calcineurin-regulated; ketoconazole, caspofungin induced; Spider biofilm induced; flow biofilm repressed || 1 -2.13 -2.32 -0.93 -1.08 -0.17 0.57 -2.29 -2.70 -1.37 -1.92 -0.44 0.62 -2.81 -2.43 1.49 1.06
10437 || orf19.24 || RTA2 || || Flippase; sphingolipid long chain base release; mediates calcineurin-dependent resistance to azoles; stress-associate; Plc1, Ca2+, calcineurin-regulated; ketoconazole, caspofungin induced; Spider biofilm induced; flow biofilm repressed || 1 -1.69 -1.61 -1.21 -1.47 -0.26 0.60 -1.86 -2.17 -1.44 -2.06 -0.51 0.70 -1.72 -1.94 1.39 1.26
10438 || orf19.24 || RTA2 || || Flippase; sphingolipid long chain base release; mediates calcineurin-dependent resistance to azoles; stress-associate; Plc1, Ca2+, calcineurin-regulated; ketoconazole, caspofungin induced; Spider biofilm induced; flow biofilm repressed || 1 -1.95 -1.97 -1.39 -1.52 -0.57 0.47 -1.43 -2.10 -2.04 -1.74 -0.60 0.38 -2.36 -2.04 1.09 1.08
10439 || orf19.2947 || SNZ1 || || Stationary phase protein; vitamin B synthesis; induced byyeast-hypha switch, 3-AT or in azole-resistant strain overexpressing MDR1; soluble in hyphae; regulated by Gcn4, macrophage; Spider biofilm induced; rat catheter biofilm repressed || 1 -2.36 -2.31 -2.28 -1.69 -1.13 0.27 -1.92 -2.87 -2.20 -2.88 -0.03 0.77 -2.75 -3.12 1.93 -0.03
10440 || orf19.2947 || SNZ1 || || Stationary phase protein; vitamin B synthesis; induced byyeast-hypha switch, 3-AT or in azole-resistant strain overexpressing MDR1; soluble in hyphae; regulated by Gcn4, macrophage; Spider biofilm induced; rat catheter biofilm repressed || 1 -1.83 -1.67 -1.74 -1.09 -0.57 1.00 -1.46 -2.17 -1.31 -2.21 0.27 1.80 -2.11 -2.15 2.46 0.40
10441 || orf19.851 || || || Protein of unknown function; repressed by Rim101; negatively modulates intracellular ATP levels during the development of azole resistance; induced by Ca(2+) in a calcineurin-dependent manner; Spider biofilm induced || 1 -1.15 -2.02 -1.08 -1.20 -0.35 0.01 -1.22 -1.48 -1.85 -1.45 0.41 1.46 -1.38 -1.09 1.62 0.66
10442 || orf19.1258 || || || Adhesin-like protein; regulated by Tsa1, Tsa1B in minimal media at 37 deg; clade-associated gene expression; induced by alpha pheromone in SpiderM medium; Hap43-induced; Spider biofilm repressed || 1 -2.33 -1.99 -3.34 -3.64 -0.80 -0.51 -2.52 -3.06 -3.98 -3.69 0.79 1.41 -2.20 -3.81 1.81 0.23
10443 || orf19.1258 || || || Adhesin-like protein; regulated by Tsa1, Tsa1B in minimal media at 37 deg; clade-associated gene expression; induced by alpha pheromone in SpiderM medium; Hap43-induced; Spider biofilm repressed || 1 -3.27 -3.11 -3.90 -4.35 -0.07 0.24 -3.15 -3.28 -3.91 -3.96 1.11 2.01 -2.87 -4.45 2.34 0.68
10444 || orf19.1189 || || || Protein of unknown function; regulated by yeast-hypha switch; induced by Mnl1 in weak acid stress; 5' UTR intron; repressed by chlamydospore formation in C. albicans and C. dubliniensis; rat catheter, Spider and flow model biofilm induced || 1 -1.48 -1.30 -1.81 -2.57 1.14 1.99 -2.79 -2.84 -2.24 -3.45 1.98 1.64 -1.27 -4.18 2.00 1.99
10445 || orf19.7251 || WSC4 || || Putative cell wall integrity and stress response subunit 4 precursor; transcription is specific to white cell type || 1 -1.20 -1.39 -1.40 -2.17 0.58 1.30 -1.40 -1.67 -1.63 -2.95 0.56 0.37 -0.39 -1.52 0.90 0.97
10446 || orf19.7251 || WSC4 || || Putative cell wall integrity and stress response subunit 4 precursor; transcription is specific to white cell type || 1 -1.40 -1.17 -1.19 -1.74 1.06 1.52 -1.44 -1.53 -1.57 -2.83 0.80 0.33 0.05 -2.00 1.05 0.60
10447 || orf19.4216 || || || Putative heat shock protein; decreased expression in hyphae; transcription is increased in populations of cells exposed to fluconazole over multiple generations; overexpression increases resistance to farnesol and azoles || 1 -2.83 -2.75 -4.40 -4.75 2.39 -2.69 -3.13 -4.82 -5.14 2.44 -1.69 -5.84 3.80 1.27
10448 || orf19.3160 || HSP12 || || Heat-shock protein; induced by osmotic/oxidative/cadmium stress, fluphenazine treatment, low iron, CDR1 and CDR2 overexpression, or ssn6 or ssk1 null mutation; overexpression increases resistance to farnesol and azoles || 1 -2.79 -2.83 -4.34 -4.53 2.44 -2.74 -3.06 -4.98 -4.98 2.48 -1.72 -5.79 3.67 0.97
10449 || orf19.3160 || HSP12 || || Heat-shock protein; induced by osmotic/oxidative/cadmium stress, fluphenazine treatment, low iron, CDR1 and CDR2 overexpression, or ssn6 or ssk1 null mutation; overexpression increases resistance to farnesol and azoles || 1 -3.01 -2.86 -3.78 -4.60 2.46 2.88 -3.32 -3.45 -4.79 -5.29 2.57 1.84 -1.84 -6.01 3.61 1.21
10450 || orf19.4216 || || || Putative heat shock protein; decreased expression in hyphae; transcription is increased in populations of cells exposed to fluconazole over multiple generations; overexpression increases resistance to farnesol and azoles || 1 -3.04 -3.27 -2.60 -4.34 2.40 2.87 -3.20 -3.34 -4.22 -3.47 2.37 1.88 -1.74 -4.97 3.68 1.22
10451 || orf19.4216 || || || Putative heat shock protein; decreased expression in hyphae; transcription is increased in populations of cells exposed to fluconazole over multiple generations; overexpression increases resistance to farnesol and azoles || 1 -4.57 -4.39 -4.40 -5.49 2.62 -5.09 -4.86 -5.76 -5.76 2.55 2.00 -2.20 -6.89 3.81 1.31
10452 || orf19.3160 || HSP12 || || Heat-shock protein; induced by osmotic/oxidative/cadmium stress, fluphenazine treatment, low iron, CDR1 and CDR2 overexpression, or ssn6 or ssk1 null mutation; overexpression increases resistance to farnesol and azoles || 1 -5.07 -5.21 -5.28 -5.59 2.26 2.84 -5.59 -5.21 -6.09 -5.99 2.45 1.94 -2.41 -7.01 3.42 1.01
10453 || orf19.4216 || || || Putative heat shock protein; decreased expression in hyphae; transcription is increased in populations of cells exposed to fluconazole over multiple generations; overexpression increases resistance to farnesol and azoles || 1 -4.94 -4.84 -5.28 -5.95 2.35 2.69 -5.40 -5.36 -6.02 -5.99 2.43 1.73 -2.52 -7.27 3.58 1.19
10454 || orf19.4216 || || || Putative heat shock protein; decreased expression in hyphae; transcription is increased in populations of cells exposed to fluconazole over multiple generations; overexpression increases resistance to farnesol and azoles || 1 -4.77 -4.86 -5.63 -5.73 2.58 2.90 -5.75 -5.10 -6.40 -5.96 2.51 2.00 -2.45 -7.41 3.57 1.26
10455 || orf19.3160 || HSP12 || || Heat-shock protein; induced by osmotic/oxidative/cadmium stress, fluphenazine treatment, low iron, CDR1 and CDR2 overexpression, or ssn6 or ssk1 null mutation; overexpression increases resistance to farnesol and azoles || 1 -4.60 -4.48 -5.64 -5.67 2.55 -5.11 -4.72 -5.88 -5.91 2.46 2.04 -2.15 -6.76 3.80 0.83
10456 || orf19.3160 || HSP12 || || Heat-shock protein; induced by osmotic/oxidative/cadmium stress, fluphenazine treatment, low iron, CDR1 and CDR2 overexpression, or ssn6 or ssk1 null mutation; overexpression increases resistance to farnesol and azoles || 1 -5.28 -5.36 -5.25 -5.73 2.24 2.71 -4.91 -4.62 -6.18 -5.38 2.32 1.77 -2.42 -6.43 3.50 0.98
10457 || orf19.1189 || || || Protein of unknown function; regulated by yeast-hypha switch; induced by Mnl1 in weak acid stress; 5' UTR intron; repressed by chlamydospore formation in C. albicans and C. dubliniensis; rat catheter, Spider and flow model biofilm induced || 1 -4.11 -4.23 -5.02 -5.13 1.41 1.71 -4.14 -4.75 -5.09 -4.52 2.32 1.52 -3.33 -4.92 2.59 1.80
10458 || orf19.1189 || || || Protein of unknown function; regulated by yeast-hypha switch; induced by Mnl1 in weak acid stress; 5' UTR intron; repressed by chlamydospore formation in C. albicans and C. dubliniensis; rat catheter, Spider and flow model biofilm induced || 1 -2.34 -2.23 -2.53 -3.20 1.26 1.81 -2.53 -2.64 -3.45 -3.50 2.07 1.60 -2.16 -3.35 2.32 1.96
10459 || orf19.1189 || || || Protein of unknown function; regulated by yeast-hypha switch; induced by Mnl1 in weak acid stress; 5' UTR intron; repressed by chlamydospore formation in C. albicans and C. dubliniensis; rat catheter, Spider and flow model biofilm induced || 1 -3.17 -3.05 -2.47 -3.90 0.89 1.47 -3.17 -2.89 -5.51 -4.58 2.13 0.93 -2.63 -3.84 1.51 1.61
10460 || orf19.5070 || || || Similar to cell-wall mannoproteins; induced in low iron; induced in cyr1 homozygous null; regulated by osmotic and oxidative stress via Hog1; Spider biofilm induced || 1 -2.57 -2.39 -1.98 -1.54 1.90 2.68 -2.12 -3.02 -3.04 -2.28 1.10 0.70 -1.86 -2.25 1.25 0.03
10461 || orf19.7284 || ASR2 || || Adenylyl cyclase and stress responsive protein; induced in cyr1 or ras1 mutant; stationary phase enriched protein; Spider biofilm induced || 1 -4.02 -3.94 -3.96 -4.00 2.82 3.22 -3.60 -3.78 -3.45 -4.43 1.35 1.60 -3.52 -4.01 3.03 -0.22
10462 || orf19.7284 || ASR2 || || Adenylyl cyclase and stress responsive protein; induced in cyr1 or ras1 mutant; stationary phase enriched protein; Spider biofilm induced || 1 -3.11 -2.97 -2.99 -3.40 2.68 3.22 -2.93 -3.03 -3.22 -3.88 1.35 1.83 -3.07 -3.48 2.84 0.16
10463 || orf19.1182 || || || Ortholog(s) have SNAP receptor activity, phosphatidylinositol-3-phosphate binding activity and role in piecemeal microautophagy of nucleus, vacuole fusion, non-autophagic, vesicle fusion || 1 -0.83 -0.93 -0.60 -0.73 0.53 1.00 -0.96 -0.85 -0.59 -0.65 0.45 0.60 -0.90 -0.77 0.64 0.14
10464 || orf19.2165 || || || Predicted hydrolase; induced by nitric oxide || 1 -1.52 -1.40 -1.95 -1.50 1.66 2.04 -1.44 -1.26 -1.66 -1.72 0.80 0.89 -2.12 -1.24 0.68 0.21
10465 || orf19.5782 || || || Ortholog(s) have mitochondrion localization || 1 -0.71 -0.76 -0.54 -0.54 0.84 0.70 -0.67 -0.96 -0.80 -1.05 0.65 0.10 -0.71 -0.58 0.36 0.60
10466 || orf19.5782 || || || Ortholog(s) have mitochondrion localization || 1 -0.88 -0.95 -1.00 -1.02 0.84 0.41 -0.62 -1.03 -1.14 -1.14 0.38 -0.14 -0.56 -0.94 0.25 0.70
10467 || orf19.1664 || || || Protein of unknown function; expression downregulated in an ssr1 null mutant || 1 -1.32 -1.23 -1.14 -1.05 0.29 0.37 -0.97 -1.16 -1.18 -1.69 0.26 0.04 -1.39 -0.88 -0.10 0.61
10468 || orf19.2498 || || || Predicted ubiquitin-protein ligase; Hap43-repressed gene; oxidative stress-induced via Cap1; flow model biofilm induced || 1 -1.27 -1.29 -0.63 -1.10 -0.21 0.20 -0.94 -1.01 -0.65 -1.15 0.06 0.20 -0.79 -0.81 0.59 0.70
10469 || orf19.54 || RHD1 || || Putative beta-mannosyltransferase required for the addition of beta-mannose to the acid-labile fraction of cell wall phosphopeptidomannan; 9-gene family memebr; regulated on yeast-hypha and white-opaque switches; Spider biofilm repressed || 1 -3.65 -3.59 -4.34 -4.60 1.73 1.57 -2.69 -2.66 -3.37 -3.67 1.50 1.45 -3.21 -3.81 2.43 1.85
10470 || orf19.7278 || || || Similar to a region of the Tca2 (pCal) retrotransposon, which is present in strain hOG1042 as 50 to 100 copies of a linear dsDNA; rat catheter biofilm repressed || 1 -4.87 -4.85 -4.67 -5.55 1.64 1.40 -3.32 -3.92 -4.00 -4.75 1.19 0.50 -3.48 -3.48 1.90 1.88
10471 || orf19.7278 || || || Similar to a region of the Tca2 (pCal) retrotransposon, which is present in strain hOG1042 as 50 to 100 copies of a linear dsDNA; rat catheter biofilm repressed || 1 -4.84 -4.92 -4.78 -5.26 1.82 1.78 -3.19 -3.84 -3.13 -3.94 1.58 -3.16 -2.81 2.14
10472 || orf19.3043 || || || Ortholog(s) have triglyceride lipase activity, role in triglyceride catabolic process and mitochondrion localization || 1 -2.56 -2.57 -2.04 -2.10 0.50 0.99 -1.36 -1.47 -1.52 -1.30 0.47 0.70 -1.63 -1.13 0.91 0.30
10473 || orf19.3043 || || || Ortholog(s) have triglyceride lipase activity, role in triglyceride catabolic process and mitochondrion localization || 1 -2.38 -2.38 -1.20 -1.80 0.64 0.89 -1.34 -1.43 -1.46 -1.49 0.34 0.47 -1.60 -1.45 0.63 0.69
10474 || orf19.6874 || || || Putative helix-loop-helix (HLH) transcription factor with a role in filamentous growth || 1 -1.93 -2.01 -1.63 -1.83 0.42 1.02 -1.08 -1.55 -1.67 -1.56 0.22 0.04 -1.12 -1.34 0.25 0.76
10475 || orf19.610 || EFG1 || || bHLH transcription factor; required for white-phase cell type, RPMI and Spider biofilm formation, hyphal growth, cell-wall gene regulation; roles in adhesion, virulence; Cph1 and Efg1 have role in host cytokine response; binds E-box || 1 -3.23 -3.28 -3.22 -3.38 -0.13 0.64 -2.25 -2.87 -2.74 -2.54 0.87 0.73 -1.50 -2.11 1.67 0.41
10476 || orf19.610 || EFG1 || || bHLH transcription factor; required for white-phase cell type, RPMI and Spider biofilm formation, hyphal growth, cell-wall gene regulation; roles in adhesion, virulence; Cph1 and Efg1 have role in host cytokine response; binds E-box || 1 -3.15 -3.27 -3.07 -3.10 -0.21 0.73 -2.02 -2.41 -2.36 -2.30 0.69 1.03 -1.76 -1.79 1.94 0.55
10477 || orf19.610 || EFG1 || || bHLH transcription factor; required for white-phase cell type, RPMI and Spider biofilm formation, hyphal growth, cell-wall gene regulation; roles in adhesion, virulence; Cph1 and Efg1 have role in host cytokine response; binds E-box || 1 -3.77 -3.69 -3.32 -3.46 -0.20 0.77 -2.12 -2.73 -2.50 -2.33 0.69 0.99 -1.53 -1.70 1.82 0.58
10478 || orf19.3041 || || || Ortholog(s) have ubiquitin protein ligase binding activity || 1 -1.47 -1.46 -1.27 -1.39 -0.28 0.61 -0.95 -0.76 -1.19 -1.12 0.59 0.66 -1.01 -0.69 0.43 0.53
10479 || orf19.3041 || || || Ortholog(s) have ubiquitin protein ligase binding activity || 1 -1.67 -1.62 -1.28 -1.49 -0.19 0.68 -1.26 -0.89 -1.09 -0.82 0.62 0.96 -1.09 -0.58 0.42 0.49
10480 || orf19.2726 || || || Putative plasma membrane protein; Plc1-regulated; Spider biofilm induced || 1 -3.34 -4.15 -2.79 -2.33 -0.63 0.62 -2.75 -3.58 -2.33 -2.71 0.34 0.86 -1.96 -0.81 1.05 0.37
10481 || orf19.2726 || || || Putative plasma membrane protein; Plc1-regulated; Spider biofilm induced || 1 -3.33 -4.05 -3.14 -2.64 -0.58 0.30 -3.13 -3.86 -2.96 -2.49 0.26 0.66 -2.56 -1.31 0.78 0.36
10482 || orf19.2726 || || || Putative plasma membrane protein; Plc1-regulated; Spider biofilm induced || 1 -3.66 -3.72 -3.16 -2.40 -0.56 0.63 -2.65 -3.57 -2.67 -2.98 0.21 0.86 -2.91 -1.00 1.00 0.62
10483 || orf19.278 || || || Protein of unknown function; required for adhesion to abiotic substrate; Spider biofilm induced || 1 -1.55 -1.58 -1.62 -1.47 -0.33 0.54 -1.37 -1.58 -1.01 -1.27 -0.03 0.64 -1.51 -1.08 0.17 0.60
10484 || orf19.23 || RTA3 || || Similar to S. cerevisiae Rta1 (role in 7-aminocholesterol resistance) and Rsb1 (flippase); putative drug-responsive regulatory site; induced by fluphenazine, estradiol, ketoconazole, caspofungin; rat catheter biofilm induced || 1 -4.53 -4.29 -4.15 -3.16 -0.20 1.57 -2.82 -3.90 -2.39 -2.67 -0.57 0.18 -4.25 -2.69 1.36 0.69
10485 || orf19.610 || EFG1 || || bHLH transcription factor; required for white-phase cell type, RPMI and Spider biofilm formation, hyphal growth, cell-wall gene regulation; roles in adhesion, virulence; Cph1 and Efg1 have role in host cytokine response; binds E-box || 1 -3.55 -3.10 -3.23 -3.13 -1.04 -0.19 -2.49 -3.46 -3.08 -2.24 -0.02 -0.10 -2.21 -2.62 0.75 -0.00
10486 || orf19.4269 || || || Has domain(s) with predicted ATP binding, protein kinase activity and role in protein phosphorylation || 1 -1.23 -1.50 -1.67 -1.58 -0.03 0.04 -0.94 -1.00 -1.02 -1.02 0.17 0.27 -0.69 -0.36 0.24 0.51
10487 || orf19.2094 || PDR6 || || Putative pleiotropic drug resistance regulatory protein 6; transcript regulated by Nrg1; induced by alpha pheromone in SpiderM medium || 1 -1.44 -1.50 -1.12 -1.78 0.20 0.39 -1.12 -1.08 -0.62 -0.81 0.06 0.28 -0.95 -0.33 0.54 0.70
10488 || orf19.2094 || PDR6 || || Putative pleiotropic drug resistance regulatory protein 6; transcript regulated by Nrg1; induced by alpha pheromone in SpiderM medium || 1 -1.38 -1.47 -0.84 -1.12 0.12 0.32 -1.11 -0.82 -0.46 -0.60 -0.04 0.21 -0.79 -0.37 0.28 0.48
10489 || orf19.5587 || || || Protein of unknown function; transcript is upregulated in clinical isolates from HIV+ patients with oral candidiasis || 1 -1.74 -1.92 -0.77 -1.34 -0.04 0.39 -1.28 -1.03 -0.32 -1.18 0.40 0.81 -1.43 -1.28 0.78 0.31
10490 || orf19.5587 || || || Protein of unknown function; transcript is upregulated in clinical isolates from HIV+ patients with oral candidiasis || 1 -2.08 -1.60 -1.60 -1.56 0.13 0.50 -1.23 -0.91 -0.21 -1.08 0.53 0.70 -1.74 -1.11 1.26 0.44
10491 || orf19.6245 || || || Protein of unknown function; regulated by osmotic stress via Hog1 and oxidative stress (Hog1- and Cap1-independent); induced by alpha pheromone in SpiderM medium; Spider biofilm induced || 1 -1.94 -1.83 -1.71 -1.60 0.51 0.90 -1.26 -1.49 -0.50 -1.07 0.71 0.70 -1.35 -1.21 1.23 0.62
10492 || orf19.7214 || || || Glucan 1,3-beta-glucosidase; regulated by Nrg1, Tup1 and possibly Tac1; induced by NO and during cell wall regeneration; stationary phase enriched; possibly essential (UAU1 method); F-12/CO2 early biofilm induced; flow biofilm repressed || 1 -2.24 -2.25 -1.70 -1.45 0.38 1.02 -1.57 -1.41 -0.90 -1.06 0.25 0.79 -1.91 -0.91 1.11 -0.00
10493 || orf19.4416 || VPS13 || || Putative vacuolar protein sorting-associated protein; gene used for multilocus sequence typing || 1 -1.72 -1.81 -0.86 -0.98 0.31 0.82 -1.54 -1.50 -1.05 -1.21 0.15 0.74 -1.84 -1.21 0.87 -0.05
10494 || orf19.2165 || || || Predicted hydrolase; induced by nitric oxide || 1 -2.63 -2.56 -2.62 -2.50 1.18 1.61 -2.03 -1.92 -2.24 -1.78 0.52 0.70 -2.65 -1.21 0.42 0.02
10495 || orf19.769 || IFE1 || || Putative medium-chain alcohol dehydrogenase; rat catheter and Spider biofilm repressed || 1 -1.55 -1.55 -1.30 -1.11 0.57 1.37 -2.26 -2.00 -1.92 -1.70 0.06 0.33 -2.62 -1.78 0.38 0.33
10496 || orf19.6070 || ENA2 || || Putative sodium transporter; induced by ciclopirox olamine; alkaline induced by Rim101; repressed by high-level peroxide stress; induced in oral candidiasis clinical isolates; possibly essential gene; rat catheter and Spider biofilm induced || 1 -2.56 -2.05 -1.48 -2.20 0.21 1.27 -2.06 -1.95 -1.68 -1.40 -0.51 0.32 -1.82 -1.64 -0.05 0.58
10497 || orf19.5572 || || || Protein of unknown function; Spider biofilm repressed || 1 -1.67 -1.73 -0.75 -0.98 0.20 1.10 -1.44 -1.41 -1.27 -1.31 -0.36 0.04 -1.70 -0.66 -0.02 0.62
10498 || orf19.5572 || || || Protein of unknown function; Spider biofilm repressed || 1 -1.16 -1.12 -0.81 -1.03 0.40 0.91 -1.13 -1.30 -1.26 -1.24 -0.03 0.19 -1.06 -0.62 0.44 0.69
10499 || orf19.6817 || FCR1 || || Transcription factor; repressor of fluconazole/ketoconazole/brefeldin A resistance; Tn mutation enhances filamentation; partially rescues S. cerevisiae pdr1 pdr3 fluconazole sensitivity; rat catheter biofilm induced/Spider biofilm repressed || 1 -3.25 -3.53 -3.13 -2.55 1.19 1.84 -4.03 -3.43 -6.21 -3.54 0.14 -0.49 -2.30 -2.80 0.92 -0.32
10500 || orf19.6817 || FCR1 || || Transcription factor; repressor of fluconazole/ketoconazole/brefeldin A resistance; Tn mutation enhances filamentation; partially rescues S. cerevisiae pdr1 pdr3 fluconazole sensitivity; rat catheter biofilm induced/Spider biofilm repressed || 1 -2.87 -3.11 -2.53 -1.73 1.62 2.11 -3.80 -2.90 -4.73 -4.07 0.25 0.10 -2.44 -2.38 0.99 -0.03
10501 || orf19.822 || HSP21 || || Small heat shock protein; role in stress response and virulence; fluconazole-downregulated; induced in cyr1 or ras1 mutant; stationary phase enriched protein; detected in some, not all, biofilm extracts; Spider biofilm induced || 1 -3.92 -3.56 -2.65 -4.47 1.24 2.57 -4.44 -6.02 -5.23 -6.89 -2.44 -1.38 -3.52 -3.91 1.89 -1.39
10502 || orf19.822 || HSP21 || || Small heat shock protein; role in stress response and virulence; fluconazole-downregulated; induced in cyr1 or ras1 mutant; stationary phase enriched protein; detected in some, not all, biofilm extracts; Spider biofilm induced || 1 -3.54 -3.23 -2.55 -4.17 -4.21 -5.60 -4.72 -6.62 -2.31 -1.13 -3.01 -3.82 -1.68
10503 || orf19.6489 || FMP45 || || Predicted membrane protein induced during mating; mutation confers hypersensitivity to toxic ergosterol analog, to amphotericin B; alkaline repressed; repressed by alpha pheromone in SpiderM medium; rat catheter, Spider biofilm induced || 1 -4.76 -4.58 -3.55 -3.45 0.75 2.18 -5.40 -5.94 -4.82 -4.20 -3.59 -1.48 -3.98 -5.68 1.00 -2.57
10504 || orf19.6489 || FMP45 || || Predicted membrane protein induced during mating; mutation confers hypersensitivity to toxic ergosterol analog, to amphotericin B; alkaline repressed; repressed by alpha pheromone in SpiderM medium; rat catheter, Spider biofilm induced || 1 -4.71 -4.95 -3.76 -3.72 1.05 2.77 -5.10 -6.21 -5.35 -5.51 -3.33 -1.41 -3.36 -6.39 1.64 -2.02
10505 || orf19.6489 || FMP45 || || Predicted membrane protein induced during mating; mutation confers hypersensitivity to toxic ergosterol analog, to amphotericin B; alkaline repressed; repressed by alpha pheromone in SpiderM medium; rat catheter, Spider biofilm induced || 1 -4.58 -4.55 -2.98 -3.48 1.17 2.60 -5.16 -4.99 -5.78 -4.88 -3.20 -1.59 -3.64 1.46 -2.44
10506 || orf19.6489 || FMP45 || || Predicted membrane protein induced during mating; mutation confers hypersensitivity to toxic ergosterol analog, to amphotericin B; alkaline repressed; repressed by alpha pheromone in SpiderM medium; rat catheter, Spider biofilm induced || 1 -4.36 -4.39 -3.38 -3.21 1.13 2.70 -4.51 -4.94 -5.18 -5.79 -3.18 -1.08 -3.21 -4.52 1.39 -2.18
10507 || orf19.4943 || PSA2 || || Mannose-1-phosphate guanyltransferase; Hap43, macrophage-repressed; stationary phase enriched protein; Spider biofilm induced; rat catheter biofilm repressed || 1 -4.34 -4.29 -3.66 -4.03 1.69 2.55 -4.31 -4.77 -4.75 -5.25 -2.28 -0.57 -4.05 -4.48 1.25 -0.98
10508 || orf19.4943 || PSA2 || || Mannose-1-phosphate guanyltransferase; Hap43, macrophage-repressed; stationary phase enriched protein; Spider biofilm induced; rat catheter biofilm repressed || 1 -3.72 -4.02 -3.14 -4.41 1.75 2.45 -4.15 -5.05 -4.56 -3.40 -2.35 -0.70 -2.82 -5.09 1.53 -0.66
10509 || orf19.5204 || || || Ortholog(s) have role in cellular response to methylmercury and cytoplasm, nucleus localization || 1 -2.78 -2.79 -1.50 -2.28 0.29 1.25 -2.20 -2.83 -2.46 -2.30 -0.85 -0.09 -1.57 -2.14 0.51 0.02
10510 || orf19.5204 || || || Ortholog(s) have role in cellular response to methylmercury and cytoplasm, nucleus localization || 1 -2.30 -2.31 -1.75 -1.71 0.19 1.11 -1.71 -2.62 -2.24 -2.72 -0.74 -0.10 -1.64 -2.10 0.61 -0.16
10511 || orf19.7310 || || || Protein with a role in directing meiotic recombination events to homologous chromatids; induced by ciclopirox olamine; positively regulated by Sfu1; Hog1, fluconazole-repressed; Hap43-induced; Spider biofilm induced || 1 -4.47 -5.59 -3.56 -3.22 1.23 2.32 -5.30 -5.12 -4.12 -5.36 -0.90 -0.14 -4.62 -5.65 1.68 -1.05
10512 || orf19.2344 || ASR1 || || Heat shock protein; transcript regulated by cAMP, osmotic stress, ciclopirox olamine, ketoconazole; repressed by Cyr1, Ras1; colony morphology-related regulated by Ssn6; stationary phase enriched; Hap43-induced; Spider biofilm induced || 1 -4.38 -4.58 -3.75 -3.96 1.48 2.42 -4.45 -4.83 -4.31 -5.15 -0.69 0.14 -4.76 -5.24 1.81 -2.79
10513 || orf19.2344 || ASR1 || || Heat shock protein; transcript regulated by cAMP, osmotic stress, ciclopirox olamine, ketoconazole; repressed by Cyr1, Ras1; colony morphology-related regulated by Ssn6; stationary phase enriched; Hap43-induced; Spider biofilm induced || 1 -4.26 -4.18 -3.52 -3.85 1.44 2.57 -4.24 -4.62 -4.23 -4.90 -0.59 0.55 -4.19 -4.99 1.86 -2.66
10514 || orf19.2296 || || || Predicted mucin-like protein; ketoconazole-induced; fluconazole-repressed; induced in cyr1 mutant; colony morphology-related gene regulation by Ssn6; flow model biofilm induced; Spider biofilm induced || 1 -2.97 -3.09 -1.22 -1.21 1.47 2.31 -3.35 -3.53 -2.22 -2.31 -1.40 0.02 -2.83 -2.61 2.00 -0.68
10515 || orf19.6492 || || || Predicted protein serine/threonine kinase and/or protein tyrosine kinase; Spider biofilm induced || 1 -1.65 -2.09 -1.11 -1.05 1.06 1.49 -1.92 -2.39 -1.32 -2.07 -1.00 -0.52 -1.37 -1.23 0.92 0.17
10516 || orf19.6492 || || || Predicted protein serine/threonine kinase and/or protein tyrosine kinase; Spider biofilm induced || 1 -1.92 -1.81 -1.39 -1.34 1.06 1.62 -2.09 -2.24 -1.81 -2.00 -1.08 -0.50 -1.49 -1.30 1.08 0.20
10517 || orf19.4907 || || || Putative protein of unknown function; Hap43p-repressed gene; increased transcription is observed upon fluphenazine treatment; possibly transcriptionally regulated by Tac1p; induced by nitric oxide; fungal-specific (no human/murine homolog || 1 -1.95 -1.90 -1.61 -2.00 0.66 1.88 -2.19 -2.26 -2.45 -3.02 -0.56 -0.61 -1.86 -2.57 0.77 0.16
10518 || orf19.4907 || || || Putative protein of unknown function; Hap43p-repressed gene; increased transcription is observed upon fluphenazine treatment; possibly transcriptionally regulated by Tac1p; induced by nitric oxide; fungal-specific (no human/murine homolog || 1 -1.81 -1.89 -1.49 -2.12 0.82 1.99 -1.84 -2.10 -2.04 -2.95 -0.34 0.00 -1.76 -2.35 0.97 0.65
10519 || orf19.4907 || || || Putative protein of unknown function; Hap43p-repressed gene; increased transcription is observed upon fluphenazine treatment; possibly transcriptionally regulated by Tac1p; induced by nitric oxide; fungal-specific (no human/murine homolog || 1 -1.87 -1.87 -1.94 -2.33 1.00 2.04 -1.70 -1.84 -2.00 -2.82 -0.32 -0.43 -1.54 -2.35 1.20 0.16
10520 || orf19.347 || RSN1 || || Protein of unknown function; flow model biofilm induced; Spider biofilm induced; induced during the mating process; Hap43-repressed || 1 -2.12 -2.35 -2.23 -2.20 0.63 1.76 -1.74 -2.59 -2.02 -3.00 -0.55 -0.78 -1.81 -2.02 1.17 0.56
10521 || orf19.347 || RSN1 || || Protein of unknown function; flow model biofilm induced; Spider biofilm induced; induced during the mating process; Hap43-repressed || 1 -3.10 -3.07 -2.91 -3.25 0.97 1.82 -2.91 -4.18 -3.15 -2.79 -0.56 -0.87 -1.83 -2.43 1.36 0.77
10522 || orf19.3038 || TPS2 || || Trehalose-6-phosphate (Tre6P) phosphatase; mutant heat sensitive, accumulates Tre6P, decreased mouse virulence; possible drug target; 2 conserved phospohydrolase motifs; no mammalian homolog; Hap43-repressed; flow model biofilm induced || 1 -1.61 -1.60 -0.86 -1.53 0.78 1.22 -1.15 -1.73 -0.72 -1.90 -0.72 -0.14 -0.64 -0.97 0.63 0.29
10523 || orf19.3038 || TPS2 || || Trehalose-6-phosphate (Tre6P) phosphatase; mutant heat sensitive, accumulates Tre6P, decreased mouse virulence; possible drug target; 2 conserved phospohydrolase motifs; no mammalian homolog; Hap43-repressed; flow model biofilm induced || 1 -1.68 -1.73 -1.02 -1.61 0.94 1.14 -1.07 -1.73 -0.86 -2.12 -0.48 0.10 -0.50 -1.06 0.89 0.41
10524 || orf19.6637 || || || Predicted glycosyl hydrolase; hypoxia induced; flow model biofilm induced || 1 -1.21 -1.24 -1.04 -1.12 0.19 0.69 -1.04 -1.32 -0.91 -1.39 -0.45 0.17 -0.56 -0.89 0.99 0.23
10525 || orf19.734 || GLK1 || || Putative glucokinase; transcript regulated upon yeast-hyphal switch; Efg1 regulated; fluconazole-induced; induced in core stress response; colony morphology-related gene regulation by Ssn6; GlcNAc-induced protein || 1 -1.77 -1.87 -1.38 -1.89 0.37 1.11 -1.74 -2.17 -1.33 -2.47 -0.30 0.06 -1.35 -1.50 0.99 0.45
10526 || orf19.734 || GLK1 || || Putative glucokinase; transcript regulated upon yeast-hyphal switch; Efg1 regulated; fluconazole-induced; induced in core stress response; colony morphology-related gene regulation by Ssn6; GlcNAc-induced protein || 1 -1.39 -1.29 -1.43 -1.27 0.55 1.17 -1.43 -1.89 -1.12 -2.39 -0.02 0.24 -0.85 -1.03 1.10 0.45
10527 || orf19.6116 || GLK4 || || Putative glucokinase; decreased expression in hyphae compared to yeast-form cells || 1 -1.33 -1.52 -1.38 -1.71 0.64 1.33 -1.59 -2.09 -1.00 -2.20 0.09 0.49 -0.98 -0.98 1.14 0.82
10528 || orf19.734 || GLK1 || || Putative glucokinase; transcript regulated upon yeast-hyphal switch; Efg1 regulated; fluconazole-induced; induced in core stress response; colony morphology-related gene regulation by Ssn6; GlcNAc-induced protein || 1 -1.64 -1.75 -1.64 -2.04 0.75 1.52 -1.61 -2.07 -1.04 -2.44 -0.02 0.56 -0.83 -0.97 1.34 0.69
10529 || orf19.734 || GLK1 || || Putative glucokinase; transcript regulated upon yeast-hyphal switch; Efg1 regulated; fluconazole-induced; induced in core stress response; colony morphology-related gene regulation by Ssn6; GlcNAc-induced protein || 1 -1.81 -1.82 -1.84 -2.40 0.67 1.43 -1.65 -2.06 -1.08 -2.30 0.15 0.41 -1.14 -1.42 1.33 0.67
10530 || orf19.220 || PIR1 || || 1,3-beta-glucan-linked cell wall protein; N-mannosylated, O-glycosylated by Pmt1; cell wall defect in het mutant; Hog1/fluconazole/hypoxia induced; iron/Efg1/Plc1/temp regulated; flow model biofilm induced; hyphal, Spider biofilm repressed || 1 -1.92 -2.05 -1.59 -1.08 0.44 0.93 -1.32 -1.74 -0.93 -1.89 -0.53 0.35 -1.20 -0.83 1.28 0.32
10531 || orf19.1481 || HAP42 || || Predicted transcription factor; possibly an essential gene, disruptants not obtained by UAU1 method || 1 -1.21 -1.19 -0.87 -1.01 0.33 0.38 -1.04 -1.05 -0.67 -0.65 -0.37 -0.01 -1.04 -0.36 0.44 -0.15
10532 || orf19.4816 || || || Protein of unknown function; induced by nitric oxide || 1 -1.87 -2.09 -1.54 -2.11 1.25 1.97 -1.74 -1.87 -1.11 -1.54 -0.97 -0.31 -2.08 -0.97 1.09 -0.07
10533 || orf19.4438 || RME1 || || Zinc finger protein; controls meiosis in S. cerevisae; white-specific transcript; upregulation correlates with clinical development of fluconazole resistance; Upc2-regulated in hypoxia; flow model biofilm induced; Spider biofilm repressed || 1 -3.47 -3.30 -2.06 -2.54 1.67 2.35 -3.06 -3.17 -2.30 -2.82 -1.41 -0.46 -3.20 -2.82 1.16 -0.11
10534 || orf19.4438 || RME1 || || Zinc finger protein; controls meiosis in S. cerevisae; white-specific transcript; upregulation correlates with clinical development of fluconazole resistance; Upc2-regulated in hypoxia; flow model biofilm induced; Spider biofilm repressed || 1 -4.49 -4.48 -3.00 -3.61 1.55 2.41 -3.50 -3.40 -2.86 -3.70 -1.79 -0.77 -4.07 -2.71 1.17 0.05
10535 || orf19.4438 || RME1 || || Zinc finger protein; controls meiosis in S. cerevisae; white-specific transcript; upregulation correlates with clinical development of fluconazole resistance; Upc2-regulated in hypoxia; flow model biofilm induced; Spider biofilm repressed || 1 -4.78 -4.93 -4.52 -4.34 1.58 2.12 -4.30 -4.46 -2.97 -4.28 -1.71 -1.03 -4.27 -3.91 1.46 0.21
10536 || orf19.4438 || RME1 || || Zinc finger protein; controls meiosis in S. cerevisae; white-specific transcript; upregulation correlates with clinical development of fluconazole resistance; Upc2-regulated in hypoxia; flow model biofilm induced; Spider biofilm repressed || 1 -3.74 -3.87 -3.39 -4.13 1.78 2.26 -3.39 -3.88 -2.32 -3.19 -1.44 -0.90 -3.63 -2.80 1.16 0.17
10537 || orf19.4438 || RME1 || || Zinc finger protein; controls meiosis in S. cerevisae; white-specific transcript; upregulation correlates with clinical development of fluconazole resistance; Upc2-regulated in hypoxia; flow model biofilm induced; Spider biofilm repressed || 1 -4.16 -4.20 -3.34 -5.89 1.89 2.29 -3.58 -4.10 -2.08 -4.41 -1.46 -0.52 -3.82 -3.24 1.42 0.44
10538 || orf19.84 || CAN3 || || Predicted amino acid transmembrane transporter; transcript regulated by white-opaque switch; Hap43-repressed gene || 1 -3.53 -3.50 -3.55 -3.12 0.28 0.77 -3.93 -3.72 -3.80 -3.66 -1.15 0.10 -3.15 -2.42 1.67 1.25
10539 || orf19.4212 || FET99 || || Multicopper oxidase family protein; similar to S. cerevisiae Fet3; does not complement S. cerevisiae fet3 mutant growth under low-iron; iron-repressed; regulated by Tup1, Rim101; flow model biofilm induced; Spider biofilm repressed || 1 -3.60 -3.51 -3.01 -3.83 0.01 0.66 -3.94 -4.03 -4.16 -5.26 0.71 0.79 -2.79 -3.89 0.63 1.48
10540 || orf19.868 || ADAEC || || Protein of unknown function; transcription is specific to white cell type || 1 -4.52 -4.64 -3.86 -4.32 1.00 1.62 -5.91 -5.87 -6.03 -4.86 1.21 1.12 -2.55 -6.47 1.89 0.65
10541 || orf19.868 || ADAEC || || Protein of unknown function; transcription is specific to white cell type || 1 -4.52 -4.52 -4.53 -4.66 1.01 1.77 -5.01 -5.55 -5.32 -5.51 1.43 1.17 -2.86 -6.22 2.04 1.05
10542 || orf19.868 || ADAEC || || Protein of unknown function; transcription is specific to white cell type || 1 -4.06 -3.97 -3.48 -3.86 0.67 1.48 -4.31 -4.20 -4.52 -5.12 0.74 0.88 -2.96 -5.34 1.45 0.62
10543 || orf19.868 || ADAEC || || Protein of unknown function; transcription is specific to white cell type || 1 -5.45 -5.50 -3.91 -4.94 0.26 1.22 -6.61 -6.04 -6.54 -6.10 0.22 0.44 -3.44 -7.32 1.06 0.68
10544 || orf19.868 || ADAEC || || Protein of unknown function; transcription is specific to white cell type || 1 -5.36 -5.69 -4.16 -4.78 0.28 1.49 -5.00 -4.50 -4.91 -4.92 0.44 0.61 -3.52 -4.94 1.17 0.65
10545 || orf19.1979 || GIT3 || || Glycerophosphocholine permease; white cell specific transcript; fungal-specific; alkaline repressed; caspofungin, macrophage/pseudohyphal-repressed; flow model biofilm induced; Spider biofilm induced || 1 -6.14 -6.40 -5.37 -5.47 1.09 2.09 -6.56 -5.52 -7.20 -6.69 -0.24 0.35 -5.17 -8.94 0.93 -0.48
10546 || orf19.3548.1 || WH11 || || White-phase yeast transcript; expression in opaques increases virulence/switching; mutant switches as WT; Hap43, hypoxia, ketoconazol induced; required for RPMI biofilm; Bcr1-induced in RPMI a/a biofilm; rat catheter, Spider biofilm induced || 1 -7.36 -7.62 -7.63 -7.16 1.48 -9.45 -7.56 -8.89 -7.19 0.35 0.16 -7.51 -8.57 -0.94
10547 || orf19.3548.1 || WH11 || || White-phase yeast transcript; expression in opaques increases virulence/switching; mutant switches as WT; Hap43, hypoxia, ketoconazol induced; required for RPMI biofilm; Bcr1-induced in RPMI a/a biofilm; rat catheter, Spider biofilm induced || 1 -6.56 -6.98 -6.65 -6.75 2.38 2.43 -8.19 -6.53 -7.50 -6.93 0.87 0.79 -6.17 -8.45 2.90 -0.47
10548 || orf19.3548.1 || WH11 || || White-phase yeast transcript; expression in opaques increases virulence/switching; mutant switches as WT; Hap43, hypoxia, ketoconazol induced; required for RPMI biofilm; Bcr1-induced in RPMI a/a biofilm; rat catheter, Spider biofilm induced || 1 -7.07 -7.44 -6.81 -7.16 2.11 2.27 -8.40 -6.96 -7.89 -6.88 0.69 0.53 -7.05 -8.07 2.79 -0.67
10549 || orf19.3548.1 || WH11 || || White-phase yeast transcript; expression in opaques increases virulence/switching; mutant switches as WT; Hap43, hypoxia, ketoconazol induced; required for RPMI biofilm; Bcr1-induced in RPMI a/a biofilm; rat catheter, Spider biofilm induced || 1 -6.71 -7.16 -6.80 -7.16 2.04 2.36 -7.30 -6.96 -8.37 -7.07 0.71 0.57 -6.74 -7.95 2.77 -0.25
10550 || orf19.3548.1 || WH11 || || White-phase yeast transcript; expression in opaques increases virulence/switching; mutant switches as WT; Hap43, hypoxia, ketoconazol induced; required for RPMI biofilm; Bcr1-induced in RPMI a/a biofilm; rat catheter, Spider biofilm induced || 1 -7.04 -6.77 -7.04 -6.74 2.24 2.50 -7.18 -7.09 -8.44 -6.78 0.94 0.92 -6.88 -7.87 3.01 -0.42
10551 || orf19.4555 || ALS4 || || GPI-anchored adhesin; role in adhesion, germ tube induction; growth, temperature regulated; expressed during infection of human buccal epithelial cells; repressed by vaginal contact; biofilm induced; repressed during chlamydospore formation || 1 -4.45 -4.70 -4.59 -4.46 -4.90 -4.65 -5.36 -5.45 0.06 0.41 -4.92 -5.85 1.35 -0.10
10552 || orf19.4555 || ALS4 || || GPI-anchored adhesin; role in adhesion, germ tube induction; growth, temperature regulated; expressed during infection of human buccal epithelial cells; repressed by vaginal contact; biofilm induced; repressed during chlamydospore formation || 1 -4.17 -4.46 -4.03 -4.83 1.40 2.23 -4.56 -4.02 -5.00 -4.73 0.64 0.16 -4.24 -5.82 1.27 -0.01
10553 || orf19.4555 || ALS4 || || GPI-anchored adhesin; role in adhesion, germ tube induction; growth, temperature regulated; expressed during infection of human buccal epithelial cells; repressed by vaginal contact; biofilm induced; repressed during chlamydospore formation || 1 -4.52 -4.34 -4.53 -4.67 -4.72 -5.34 0.49 0.62 -4.51 -5.32 1.54 0.35
10554 || orf19.4555 || ALS4 || || GPI-anchored adhesin; role in adhesion, germ tube induction; growth, temperature regulated; expressed during infection of human buccal epithelial cells; repressed by vaginal contact; biofilm induced; repressed during chlamydospore formation || 1 -4.51 -4.44 -5.36 -5.28 1.33 1.92 -4.47 -4.68 -5.01 -5.29 0.24 0.25 -4.41 -5.74 1.48 0.10
10555 || orf19.4555 || ALS4 || || GPI-anchored adhesin; role in adhesion, germ tube induction; growth, temperature regulated; expressed during infection of human buccal epithelial cells; repressed by vaginal contact; biofilm induced; repressed during chlamydospore formation || 1 -4.96 -5.04 -5.32 -5.74 1.09 1.80 -4.95 -4.97 -5.68 -5.59 0.30 0.25 -5.10 -5.70 1.22 0.11
10556 || orf19.1979 || GIT3 || || Glycerophosphocholine permease; white cell specific transcript; fungal-specific; alkaline repressed; caspofungin, macrophage/pseudohyphal-repressed; flow model biofilm induced; Spider biofilm induced || 1 -4.91 -5.18 -5.66 -5.55 1.11 2.00 -4.92 -5.52 -5.35 -6.32 -0.21 0.56 -4.80 -5.99 1.05 0.08
10557 || orf19.1979 || GIT3 || || Glycerophosphocholine permease; white cell specific transcript; fungal-specific; alkaline repressed; caspofungin, macrophage/pseudohyphal-repressed; flow model biofilm induced; Spider biofilm induced || 1 -6.10 -5.42 -5.40 -5.98 0.98 2.01 -4.84 -5.81 -5.67 -5.66 -0.32 0.55 -5.04 -6.10 1.01 0.07
10558 || orf19.7310 || || || Protein with a role in directing meiotic recombination events to homologous chromatids; induced by ciclopirox olamine; positively regulated by Sfu1; Hog1, fluconazole-repressed; Hap43-induced; Spider biofilm induced || 1 -5.18 -5.24 -4.80 -4.88 1.40 2.61 -4.88 -4.79 -4.87 -5.29 -0.88 0.34 -4.61 -5.28 1.91 -1.03
10559 || orf19.6817 || FCR1 || || Transcription factor; repressor of fluconazole/ketoconazole/brefeldin A resistance; Tn mutation enhances filamentation; partially rescues S. cerevisiae pdr1 pdr3 fluconazole sensitivity; rat catheter biofilm induced/Spider biofilm repressed || 1 -3.14 -3.05 -3.19 -3.17 1.00 1.79 -3.29 -3.36 -3.42 -4.16 -0.02 -0.09 -3.08 -2.60 0.70 0.04
10560 || orf19.23 || RTA3 || || Similar to S. cerevisiae Rta1 (role in 7-aminocholesterol resistance) and Rsb1 (flippase); putative drug-responsive regulatory site; induced by fluphenazine, estradiol, ketoconazole, caspofungin; rat catheter biofilm induced || 1 -3.50 -3.54 -2.74 -2.91 0.11 1.77 -2.80 -2.85 -4.29 -2.76 -0.09 0.28 -3.68 -2.62 1.68 0.46
10561 || orf19.23 || RTA3 || || Similar to S. cerevisiae Rta1 (role in 7-aminocholesterol resistance) and Rsb1 (flippase); putative drug-responsive regulatory site; induced by fluphenazine, estradiol, ketoconazole, caspofungin; rat catheter biofilm induced || 1 -2.48 -2.92 -2.19 -2.48 0.03 1.69 -2.11 -2.33 -3.43 -3.07 -0.10 0.42 -2.62 -2.59 1.56 0.45
10562 || orf19.23 || RTA3 || || Similar to S. cerevisiae Rta1 (role in 7-aminocholesterol resistance) and Rsb1 (flippase); putative drug-responsive regulatory site; induced by fluphenazine, estradiol, ketoconazole, caspofungin; rat catheter biofilm induced || 1 -2.60 -2.31 -1.86 -1.91 0.37 1.98 -2.25 -2.51 -2.77 -2.95 0.19 0.78 -2.38 -2.34 1.99 0.58
10563 || orf19.4416 || VPS13 || || Putative vacuolar protein sorting-associated protein; gene used for multilocus sequence typing || 1 -1.47 -1.62 -1.14 -1.54 0.18 0.26 -1.24 -1.34 -1.25 -1.36 0.38 0.38 -1.80 -1.62 0.94 0.16
10564 || orf19.54 || RHD1 || || Putative beta-mannosyltransferase required for the addition of beta-mannose to the acid-labile fraction of cell wall phosphopeptidomannan; 9-gene family memebr; regulated on yeast-hypha and white-opaque switches; Spider biofilm repressed || 1 -2.51 -2.69 -2.04 -2.74 0.68 1.01 -2.33 -2.92 -3.00 -2.93 0.68 1.23 -3.38 -3.07 2.04 1.50
10565 || orf19.3803 || MNN22 || || Alpha-1,2-mannosyltransferase; required for normal cell wall mannan; regulated by Tsa1, Tsa1B at 37 deg; repressed in core stress response; NO, Hog1 induced; confers sensitivity to cell wall perturbing agents; Spider biofilm repressed || 1 -2.80 -2.88 -2.75 -3.36 0.10 0.72 -2.99 -3.32 -3.46 -3.90 0.41 0.48 -3.41 -4.32 1.69 1.54
10566 || orf19.3803 || MNN22 || || Alpha-1,2-mannosyltransferase; required for normal cell wall mannan; regulated by Tsa1, Tsa1B at 37 deg; repressed in core stress response; NO, Hog1 induced; confers sensitivity to cell wall perturbing agents; Spider biofilm repressed || 1 -1.81 -3.49 -2.67 -2.74 1.15 1.21 -2.53 -2.85 -3.85 -3.89 1.49 0.53 -3.80 -4.82 2.16 1.33
10567 || orf19.5070 || || || Similar to cell-wall mannoproteins; induced in low iron; induced in cyr1 homozygous null; regulated by osmotic and oxidative stress via Hog1; Spider biofilm induced || 1 -2.56 -2.83 -1.91 -2.25 1.65 2.25 -2.83 -2.79 -3.20 -1.30 0.68 0.00 -1.93 -2.90 0.71 -0.72
10568 || orf19.6271 || || || Ortholog(s) have role in mRNA splicing, via spliceosome and nucleus, transcriptionally active chromatin localization || 1 -0.99 -0.92 -0.36 -0.53 0.28 0.71 -1.00 -0.97 -1.11 -0.52 0.22 0.16 -0.52 -0.57 -0.09 0.09
10569 || orf19.1395 || || || Ortholog(s) have inorganic phosphate transmembrane transporter activity, role in phosphate ion transport, transmembrane transport and mitochondrion localization || 1 -1.30 -1.64 -0.76 -0.67 -0.38 0.99 -1.83 -1.74 -1.58 -2.10 0.57 0.61 -1.36 -1.94 0.53 0.56
10570 || orf19.1395 || || || Ortholog(s) have inorganic phosphate transmembrane transporter activity, role in phosphate ion transport, transmembrane transport and mitochondrion localization || 1 -1.11 -1.23 -0.67 -0.57 0.06 1.26 -1.39 -1.48 -1.13 -1.82 0.72 0.51 -0.90 -1.93 0.54 0.42
10571 || orf19.23 || RTA3 || || Similar to S. cerevisiae Rta1 (role in 7-aminocholesterol resistance) and Rsb1 (flippase); putative drug-responsive regulatory site; induced by fluphenazine, estradiol, ketoconazole, caspofungin; rat catheter biofilm induced || 1 -1.07 -0.90 -0.28 -0.47 0.15 1.40 -1.07 -1.54 -1.17 -1.65 -0.07 0.51 -1.20 -1.81 1.44 0.54
10572 || orf19.6840 || || || Protein of unknown function; transcript detected in high-resolution tiling arrays; transcription induced by alpha pheromone in SpiderM medium; Spider and early-stage flow model biofilm induced || 1 -1.40 -1.41 -1.01 -0.79 0.67 1.55 -1.80 -2.04 -1.96 -2.20 -0.05 0.42 -1.67 -2.83 1.53 0.68
10573 || orf19.5612 || BMT4 || || Beta-mannosyltransferase; for elongation of beta-mannose chains on the acid-labile fraction of cell wall phosphopeptidomannan; 9-gene family member; regulated by Tsa1, Tsa1B; flow model biofilm induced; rat catheter biofilm repressed || 1 -1.70 -1.87 -1.70 -1.32 0.89 1.61 -1.57 -2.73 -2.10 -2.66 0.43 0.50 -3.28 -3.30 1.11 0.81
10574 || orf19.5612 || BMT4 || || Beta-mannosyltransferase; for elongation of beta-mannose chains on the acid-labile fraction of cell wall phosphopeptidomannan; 9-gene family member; regulated by Tsa1, Tsa1B; flow model biofilm induced; rat catheter biofilm repressed || 1 -1.29 -1.05 -0.87 -1.02 1.05 1.86 -1.13 -2.03 -1.54 -2.18 0.72 0.82 -2.37 -2.64 1.23 0.97
10575 || orf19.1182 || || || Ortholog(s) have SNAP receptor activity, phosphatidylinositol-3-phosphate binding activity and role in piecemeal microautophagy of nucleus, vacuole fusion, non-autophagic, vesicle fusion || 1 -0.45 -0.46 -0.59 -0.39 0.44 0.81 -0.78 -1.04 -0.89 -0.71 0.28 0.14 -0.34 -1.12 0.37 0.35
10576 || orf19.4317 || GRE3 || || Putative D-xylose reductase; antigenic in murine systemic infection; soluble protein in hyphae; induced by farnesol, macrophage interaction and by Mnl1 under weak acid stress; stationary-phase enriched protein; Spider biofilm induced || 1 -0.92 -0.81 -0.85 -0.97 0.28 0.89 -0.36 -1.06 -1.40 -1.58 -0.28 0.09 -1.03 -0.82 0.56 -0.05
10577 || orf19.2076 || || || Protein of unknown function; S. pombe ortholog SPAC7D4.05 encodes a predicted hydrolase; Hap43-repressed; Spider biofilm induced || 1 -0.61 -0.65 -0.96 -1.02 0.54 0.55 -1.13 -1.04 -0.58 -0.96 -0.48 0.14 -1.18 -1.36 0.65 0.17
10578 || orf19.2959.1 || || || Gene induced by hypoxia and ketoconazole; oral infection upregulated; mutants have reduced capacity to damage oral epithelial cells; Spider biofilm induced || 1 -2.00 -2.04 -0.98 -0.94 0.22 1.60 -2.18 -2.73 -1.94 -2.56 0.44 1.21 -1.05 -1.45 1.53 -0.05
10579 || orf19.2959.1 || || || Gene induced by hypoxia and ketoconazole; oral infection upregulated; mutants have reduced capacity to damage oral epithelial cells; Spider biofilm induced || 1 -1.91 -1.89 -0.92 -0.87 0.39 1.36 -1.67 -2.33 -2.27 -2.71 0.64 0.82 -0.86 -1.59 1.78 -0.46
10580 || orf19.3644 || || || Protein of unknown function; Cyr1-repressed; rat catheter and Spider biofilm induced || 1 -0.72 -0.60 -0.58 -0.51 0.33 0.59 -0.65 -0.86 -0.75 -0.61 0.06 0.29 -0.34 -0.15 0.86 -0.19
10581 || orf19.348 || SKN2 || || Protein with a potential role in beta-1,6 glucan biosynthesis; similarity to Kre6 and Skn1; possibly essential, disruptants not obtained by UAU1 method; Hap43-induced; flow model biofilm induced; rat catheter biofilm repressed || 1 -1.34 -1.47 -0.83 -1.43 -0.01 0.27 -1.31 -1.46 -0.83 -1.61 -0.44 0.27 -0.93 -1.20 -0.15 -0.71
10582 || orf19.348 || SKN2 || || Protein with a potential role in beta-1,6 glucan biosynthesis; similarity to Kre6 and Skn1; possibly essential, disruptants not obtained by UAU1 method; Hap43-induced; flow model biofilm induced; rat catheter biofilm repressed || 1 -1.31 -1.10 -0.70 -1.05 0.17 0.51 -1.37 -1.24 -1.03 -1.48 -0.32 0.53 -0.74 -1.01 0.24 -0.89
10583 || orf19.6160 || || || Ortholog(s) have role in eisosome assembly and eisosome, membrane raft, mitochondrion, plasma membrane localization || 1 -0.77 -0.76 -0.52 -0.49 -0.40 0.46 -0.92 -0.90 -0.87 -0.77 -0.26 0.06 -0.31 -0.80 0.45 0.22
10584 || orf19.446 || || || Protein of unknown function; constitutive expression independent of MTL or white-opaque status; upregulated in a cyr1 mutant || 1 -1.00 -0.92 -0.69 -0.57 0.00 0.53 -1.33 -1.47 -1.11 -0.66 -0.54 -0.13 -0.45 -0.74 0.55 -0.05
10585 || orf19.446 || || || Protein of unknown function; constitutive expression independent of MTL or white-opaque status; upregulated in a cyr1 mutant || 1 -0.91 -0.86 -0.36 -0.16 0.22 0.86 -1.29 -1.26 -0.82 -0.81 -0.41 0.08 -0.35 -0.96 0.54 -0.15
10586 || orf19.1153 || GAD1 || || Putative glutamate decarboxylase; alkaline, macrophage-downregulated gene; amphotericin B induced; induced by Mnl1 under weak acid stress; stationary phase enriched protein; rat catheter biofilm repressed || 1 -1.17 -1.37 -0.46 -1.23 0.88 1.85 -1.93 -2.54 -1.78 -3.04 -0.26 0.62 -0.34 -1.78 1.17 -0.11
10587 || orf19.1153 || GAD1 || || Putative glutamate decarboxylase; alkaline, macrophage-downregulated gene; amphotericin B induced; induced by Mnl1 under weak acid stress; stationary phase enriched protein; rat catheter biofilm repressed || 1 -1.01 -1.22 -0.78 -1.15 0.62 1.75 -1.20 -1.77 -1.44 -2.41 -0.48 0.34 -0.48 -1.83 0.85 -0.44
10588 || orf19.1152 || || || Protein of unknown function; induced in core stress response; Gcn2 and Gcn4 regulated; flow model biofilm induced; Spider biofilm induced || 1 -1.16 -1.28 -0.48 -1.33 0.26 1.39 -1.76 -2.57 -1.02 -2.15 -0.91 0.31 -1.22 -2.03 0.75 0.08
10589 || orf19.1152 || || || Protein of unknown function; induced in core stress response; Gcn2 and Gcn4 regulated; flow model biofilm induced; Spider biofilm induced || 1 -1.67 -1.74 -0.89 -1.84 0.23 1.13 -2.26 -2.91 -1.54 -2.87 -0.79 -0.09 -1.47 -2.92 0.94 -0.67
10590 || orf19.4980 || HSP70 || || Putative hsp70 chaperone; role in entry into host cells; heat-shock, amphotericin B, cadmium, ketoconazole-induced; surface localized in yeast and hyphae; antigenic in host; farnesol-downregulated in biofilm; Spider biofilm induced || 1 -2.49 -2.64 -3.11 -4.01 -3.37 -3.62 -3.40 -3.38 -1.56 -0.63 -0.95 -3.48 -1.42
10591 || orf19.4980 || HSP70 || || Putative hsp70 chaperone; role in entry into host cells; heat-shock, amphotericin B, cadmium, ketoconazole-induced; surface localized in yeast and hyphae; antigenic in host; farnesol-downregulated in biofilm; Spider biofilm induced || 1 -2.79 -2.78 -3.08 -4.55 -4.66 -5.30 -4.66 -5.05 -0.22 -1.02 -4.67 -1.53
10592 || orf19.4980 || HSP70 || || Putative hsp70 chaperone; role in entry into host cells; heat-shock, amphotericin B, cadmium, ketoconazole-induced; surface localized in yeast and hyphae; antigenic in host; farnesol-downregulated in biofilm; Spider biofilm induced || 1 -1.92 -2.20 -1.85 -2.74 -3.53 -3.87 -3.55 -4.51 -1.48 0.02 -0.83 -4.17 -1.38
10593 || orf19.1153 || GAD1 || || Putative glutamate decarboxylase; alkaline, macrophage-downregulated gene; amphotericin B induced; induced by Mnl1 under weak acid stress; stationary phase enriched protein; rat catheter biofilm repressed || 1 -1.48 -1.59 -1.15 -1.75 0.62 1.40 -2.05 -2.88 -2.20 -3.57 -0.47 -0.12 -0.70 -2.49 0.93 -0.54
10594 || orf19.4477 || CSH1 || || Aldo-keto reductase; role in fibronectin adhesion, cell surface hydrophobicity; regulated by temperature, growth phase, benomyl, macrophage interaction; azole resistance associated; Spider biofilm induced; rat catheter biofilm repressed || 1 -2.23 -2.38 -2.57 -3.02 1.13 2.68 -4.71 -5.77 -4.19 -4.73 -2.16 -0.69 0.16 -4.07 1.04 -0.57
10595 || orf19.4477 || CSH1 || || Aldo-keto reductase; role in fibronectin adhesion, cell surface hydrophobicity; regulated by temperature, growth phase, benomyl, macrophage interaction; azole resistance associated; Spider biofilm induced; rat catheter biofilm repressed || 1 -2.29 -2.09 -2.86 -2.82 0.78 2.30 -5.42 -6.50 -5.32 -5.11 -2.16 -0.94 0.36 -4.68 0.87 -0.85
10596 || orf19.1048 || IFD6 || || Aldo-keto reductase; similar to aryl alcohol dehydrogenases; protein increase correlates with MDR1 overexpression (not CDR1 or CDR2) in fluconazole-resistant clinical isolates; farnesol regulated; possibly essential; Spider biofilm induced || 1 -3.18 -3.51 -3.11 -3.56 2.04 2.75 -4.46 -4.79 -4.01 -3.81 -3.06 -2.42 -1.29 -4.25 0.30 -1.83
10597 || orf19.1048 || IFD6 || || Aldo-keto reductase; similar to aryl alcohol dehydrogenases; protein increase correlates with MDR1 overexpression (not CDR1 or CDR2) in fluconazole-resistant clinical isolates; farnesol regulated; possibly essential; Spider biofilm induced || 1 -1.87 -2.04 -2.24 -2.53 2.38 2.94 -3.36 -3.34 -3.29 -3.53 -2.17 -1.40 -0.02 -3.77 0.76 -1.33
10598 || orf19.7027 || || || Protein of unknown function; Spider biofilm induced || 1 -1.38 -1.20 -1.49 -1.85 1.62 1.51 -1.49 -1.87 -1.69 -2.58 -1.64 -1.38 -0.41 -2.54 0.02 -0.98
10599 || orf19.7027 || || || Protein of unknown function; Spider biofilm induced || 1 -1.77 -1.71 -1.83 -1.75 1.71 1.55 -1.03 -1.84 -1.50 -2.44 -1.87 -1.57 -0.38 -2.70 0.02 -0.99
10600 || orf19.7027 || || || Protein of unknown function; Spider biofilm induced || 1 -1.93 -1.92 -2.03 -1.77 1.88 1.96 -1.60 -2.37 -1.66 -2.75 -1.92 -1.06 -0.86 -3.14 0.47 -0.66
10601 || orf19.7027 || || || Protein of unknown function; Spider biofilm induced || 1 -1.94 -1.93 -1.56 -1.64 2.19 2.34 -1.27 -2.00 -1.24 -2.47 -1.54 -0.55 -0.69 -2.71 0.79 -0.98
10602 || orf19.2021 || HGT8 || || High-affinity glucose transporter of the major facilitator superfamily; 20 members in the C. albicans glucose transporter family; 12 probable membrane-spanning segments; gene has intron; expressed in rich medium; flow model biofilm induced || 1 -1.11 -1.01 -0.65 -1.36 0.93 1.56 -0.78 -1.19 -0.51 -1.85 -1.05 -0.50 -0.49 -0.96 0.00 -0.50
10603 || orf19.2020 || HGT6 || || Putative high-affinity MFS glucose transporter; 20 family members; induced in core stress response; fluconazole, oralpharyngeal candidasis induced; flow model biofilm induced; Spider biofilm induced || 1 -2.12 -2.06 -1.82 -2.63 1.31 -1.28 -1.81 -0.86 -2.25 -1.26 -0.60 -2.23 -2.64 -0.16 -0.88
10604 || orf19.2020 || HGT6 || || Putative high-affinity MFS glucose transporter; 20 family members; induced in core stress response; fluconazole, oralpharyngeal candidasis induced; flow model biofilm induced; Spider biofilm induced || 1 -3.49 -3.45 -3.46 -5.17 -2.97 -3.66 -2.91 -5.18 -2.56 -1.00 -3.62 -4.27 0.11 -0.82
10605 || orf19.5742 || ALS9 || || ALS family cell-surface glycoprotein; expressed during infection of human epithelial cells; confers laminin adhesion to S. cerevisiae; highly variable; putative GPI-anchor; Hap43-repressed || 1 -1.51 -1.38 -1.82 -2.73 0.06 1.86 -0.92 -1.31 -1.75 -2.65 -0.32 -0.30 -0.98 -1.74 -0.28 -0.43
10606 || orf19.5742 || ALS9 || || ALS family cell-surface glycoprotein; expressed during infection of human epithelial cells; confers laminin adhesion to S. cerevisiae; highly variable; putative GPI-anchor; Hap43-repressed || 1 -1.31 -1.40 -1.73 -2.59 0.07 1.71 -1.05 -1.25 -1.27 -2.47 -0.62 -0.58 -0.66 -1.80 -0.40 -0.44
10607 || orf19.5742 || ALS9 || || ALS family cell-surface glycoprotein; expressed during infection of human epithelial cells; confers laminin adhesion to S. cerevisiae; highly variable; putative GPI-anchor; Hap43-repressed || 1 -1.29 -1.24 -1.82 -2.08 0.05 1.90 -0.90 -1.23 -1.64 -2.54 -0.52 -0.68 -0.62 -2.14 -0.23 -0.42
10608 || orf19.2014 || BCY1 || || Protein kinase A regulatory subunit; required for nuclear localization of Tpk1; physically interacts with Tpk1; essential; apoptosis-regulated; bcy1 heterozygous or bcy1 tpk2 mutant has filamentous growth defect || 1 -0.40 -0.42 -0.39 -0.38 0.22 0.18 -0.53 -0.55 -0.71 -0.63 -0.17 -0.18 -0.54 -0.16 0.19 -0.04
10609 || orf19.243 || OXR1 || || Ortholog(s) have role in cellular response to oxidative stress and cytosol, mitochondrion, nucleus localization || 1 -0.21 -0.29 -0.57 -0.68 0.57 0.77 -0.87 -0.38 -0.69 -0.88 0.35 0.08 -0.82 -0.64 0.63 0.13
10610 || orf19.769 || IFE1 || || Putative medium-chain alcohol dehydrogenase; rat catheter and Spider biofilm repressed || 1 -0.50 -0.61 -0.30 -0.15 0.81 1.68 -1.10 -1.06 -1.66 -1.23 0.10 0.62 -1.39 -1.84 0.73 0.67
10611 || orf19.3448 || || || Protein of unknown function; ketoconazole-repressed || 1 -0.65 -0.70 -1.20 -1.20 1.21 2.00 -1.24 -1.53 -2.46 -2.02 0.25 -0.02 -1.71 -2.15 0.73 0.06
10612 || orf19.3448 || || || Protein of unknown function; ketoconazole-repressed || 1 -0.61 -0.74 -1.30 -1.28 1.20 1.80 -1.32 -1.62 -2.75 -2.10 0.07 0.01 -1.67 -2.18 0.55 0.01
10613 || orf19.3448 || || || Protein of unknown function; ketoconazole-repressed || 1 -0.76 -0.76 -1.37 -1.28 1.08 1.78 -1.30 -1.76 -2.72 -2.08 0.05 0.01 -1.89 -2.35 0.64 -0.07
10614 || orf19.3448 || || || Protein of unknown function; ketoconazole-repressed || 1 -0.79 -0.75 -1.20 -1.19 1.14 1.89 -1.21 -1.50 -2.63 -1.91 -0.03 0.01 -1.69 -2.49 0.73 -0.17
10615 || orf19.3448 || || || Protein of unknown function; ketoconazole-repressed || 1 -0.87 -0.84 -1.16 -0.89 1.04 1.82 -1.28 -1.66 -2.55 -2.03 -0.13 -0.08 -1.79 -2.84 0.61 -0.45
10616 || orf19.1632 || || || Ortholog(s) have cytosol, nucleus localization || 1 -0.94 -1.17 -1.34 -1.09 0.77 1.71 -1.29 -1.60 -1.55 -1.95 0.28 0.92 -2.25 -1.57 0.88 -0.60
10617 || orf19.2737 || || || Carbohydrate kinase domain-containing protein; Spider biofilm induced || 1 -0.85 -1.23 -0.98 -1.09 1.11 1.05 -1.14 -1.63 -0.76 -1.27 0.28 0.43 -1.93 -2.25 0.92 -0.38
10618 || orf19.2737 || || || Carbohydrate kinase domain-containing protein; Spider biofilm induced || 1 -1.00 -0.93 -0.89 -0.99 1.05 1.36 -0.97 -1.39 -0.64 -1.06 0.31 0.85 -1.80 -2.36 1.13 -0.54
10619 || orf19.1621 || GPA2 || || G-protein alpha subunit; regulates filamentous growth, copper resistance; involved in cAMP-mediated glucose signaling; reports differ on role in cAMP-PKA pathway, MAP kinase cascade; Gpr1 C terminus binds Gpa2; regulates HWP1 and ECE1 || 1 -0.56 -0.34 -0.41 -0.26 -0.08 -0.02 -0.70 -0.35 -0.47 -0.40 -0.21 0.04 -0.83 -0.40 -0.09 -0.28
10620 || orf19.1274 || || || Has domain(s) with predicted DNA binding, zinc ion binding activity, role in transcription, DNA-templated and nucleus localization || 1 -0.75 -0.80 -0.65 -0.64 0.00 0.44 -0.77 -0.81 -0.59 -0.29 -0.34 0.26 -1.19 -0.71 -0.02 -0.34
10621 || orf19.1333 || SNG3 || || Putative membrane transporter; Hap43p-induced gene; mutation confers hypersensitivity to toxic ergosterol analog; shows colony morphology-related gene regulation by Ssn6p || 1 -2.19 -2.15 -1.15 -1.11 -0.42 0.70 -1.78 -1.62 -0.94 -0.70 -0.36 -0.47 -1.78 -0.69 -0.15 0.04
10622 || orf19.1333 || SNG3 || || Putative membrane transporter; Hap43p-induced gene; mutation confers hypersensitivity to toxic ergosterol analog; shows colony morphology-related gene regulation by Ssn6p || 1 -2.03 -2.24 -1.66 -1.43 -0.14 0.91 -1.71 -1.53 -0.82 -0.45 0.02 -0.14 -1.67 -0.36 0.21 0.24
10623 || orf19.1333 || SNG3 || || Putative membrane transporter; Hap43p-induced gene; mutation confers hypersensitivity to toxic ergosterol analog; shows colony morphology-related gene regulation by Ssn6p || 1 -1.25 -1.60 -1.09 -0.94 0.27 0.87 -1.60 -1.32 -0.75 -0.61 0.08 -0.23 -1.32 -0.48 0.14 0.05
10624 || orf19.3332 || || || Ortholog of Bre4 in S. cerevisiae has a role in brefeldin A resistence; a drug that affect intracellular transport; Spider biofilm induced || 1 -1.14 -1.40 -0.70 -0.89 0.54 0.47 -1.94 -1.75 -0.55 -0.51 -0.12 0.38 -1.28 -0.90 0.16 0.48
10625 || orf19.5799 || || || Ortholog(s) have cytoplasm localization || 1 -0.93 -0.96 -1.18 -0.85 0.13 0.18 -1.28 -0.94 -0.56 -0.68 0.06 0.04 -1.28 -0.90 -0.19 0.59
10626 || orf19.278 || || || Protein of unknown function; required for adhesion to abiotic substrate; Spider biofilm induced || 1 -1.19 -1.68 -1.42 -1.10 -0.17 0.89 -1.77 -1.08 -1.19 -0.91 0.08 1.15 -1.29 -0.83 -0.20 0.53
10627 || orf19.6457 || || || Ortholog of S. cerevisiae : YBL086C, C. glabrata CBS138 : CAGL0C01815g, C. dubliniensis CD36 : Cd36_72270, C. parapsilosis CDC317 : CPAR2_702850 and Candida tenuis NRRL Y-1498 : CANTEDRAFT_107537 || 1 -1.26 -1.02 -1.53 -1.33 -0.03 0.20 -1.68 -2.03 -1.53 -1.17 -0.27 -0.17 -0.65 -0.75 -0.02 0.08
10628 || orf19.6423 || || || Ortholog(s) have fructose-2,6-bisphosphate 2-phosphatase activity, role in glucose metabolic process and cytoplasm localization || 1 -0.50 -0.40 -0.72 -0.66 0.11 0.37 -0.85 -0.81 -0.53 -0.26 -0.36 -0.22 -0.47 -0.15 -0.02 0.14
10629 || orf19.5416 || ESA1 || || Subunit of the NuA4 histone acetyltransferase complex; member of MYST family; Spider biofilm induced || 1 -0.76 -1.04 -0.98 -1.21 0.57 0.46 -0.41 -1.03 -1.11 -1.28 -0.62 -0.70 -0.32 -0.49 0.00 0.18
10630 || orf19.5348 || TPS3 || || Predicted trehalose-phosphate synthase regulatory subunit; regulated by Efg1; regulated by Tsa1, Tsa1B under H2O2 stress conditions; flow model biofilm induced (reports differ) || 1 -1.36 -1.46 -1.13 -1.90 1.05 1.27 -0.67 -1.56 -1.24 -2.59 -0.26 -0.31 0.11 -0.91 0.52 0.56
10631 || orf19.5348 || TPS3 || || Predicted trehalose-phosphate synthase regulatory subunit; regulated by Efg1; regulated by Tsa1, Tsa1B under H2O2 stress conditions; flow model biofilm induced (reports differ) || 1 -1.47 -1.47 -1.16 -2.15 0.74 1.20 -0.70 -1.66 -1.19 -2.50 -0.56 -0.47 -0.12 -0.94 0.48 0.41
10632 || orf19.6874 || || || Putative helix-loop-helix (HLH) transcription factor with a role in filamentous growth || 1 -0.89 -0.90 -0.26 -0.90 0.38 0.64 -0.45 -0.89 -0.93 -1.08 0.04 -0.23 -0.24 -0.91 0.13 0.13
10633 || orf19.5288 || IFE2 || || Putative alcohol dehydrogenase; yeast-enriched transcript; Efg1-regulated; induced by prostaglandins, Hog1, fluconazole; rat catheter biofilm induced || 1 -1.37 -1.09 -1.69 -4.64 0.90 1.43 -2.34 -3.31 -2.65 -5.28 -0.75 0.27 -0.48 -2.02 1.42 0.98
10634 || orf19.5288 || IFE2 || || Putative alcohol dehydrogenase; yeast-enriched transcript; Efg1-regulated; induced by prostaglandins, Hog1, fluconazole; rat catheter biofilm induced || 1 -1.41 -1.24 -1.24 -4.29 0.86 1.46 -2.31 -3.24 -2.32 -4.52 -0.66 0.62 -0.68 -1.54 1.42 1.34
10635 || orf19.4145 || ZCF20 || || Zn(II)2Cys6 transcription factor orthologous to S. cerevisiae Hap1; regulated by Sef1, Sfu1; Hap43-induced; Spider biofilm induced || 1 -0.68 -0.84 -1.05 -0.82 0.40 0.95 -1.46 -1.64 -0.85 -1.28 -0.64 0.67 -0.35 -0.82 0.41 0.82
10636 || orf19.4145 || ZCF20 || || Zn(II)2Cys6 transcription factor orthologous to S. cerevisiae Hap1; regulated by Sef1, Sfu1; Hap43-induced; Spider biofilm induced || 1 -0.98 -0.94 -0.87 -1.04 0.55 0.90 -1.44 -1.70 -1.08 -1.68 -0.31 0.37 -0.38 -1.02 0.57 0.68
10637 || orf19.6637 || || || Predicted glycosyl hydrolase; hypoxia induced; flow model biofilm induced || 1 -0.54 -0.57 -0.33 -0.78 0.27 0.90 -0.85 -1.22 -0.68 -1.30 -0.46 0.32 -0.18 -0.73 1.05 0.57
10638 || orf19.734 || GLK1 || || Putative glucokinase; transcript regulated upon yeast-hyphal switch; Efg1 regulated; fluconazole-induced; induced in core stress response; colony morphology-related gene regulation by Ssn6; GlcNAc-induced protein || 1 -0.52 -0.66 -0.45 -0.94 0.54 1.30 -0.96 -1.17 -0.42 -1.91 -0.09 0.41 -0.43 -0.88 1.08 0.76
10639 || orf19.5634 || FRP1 || || Ferric reductase; alkaline-induced by Rim101; iron-chelation-induced by CCAAT-binding factor; fluconazole-repressed; ciclopirox-, hypoxia-, Hap43-induced; colony morphology-related regulation by Ssn6; Spider and flow model biofilm induced || 1 -0.85 -1.09 -0.19 -0.93 0.57 0.94 -1.12 -1.46 -0.68 -2.13 -0.27 0.08 -0.42 -1.31 0.92 1.78
10640 || orf19.2730 || || || Has domain(s) with predicted zinc ion binding activity || 1 -1.01 -1.22 -0.44 -0.54 -0.10 0.07 -0.69 -0.61 -0.37 -1.08 0.21 -0.04 -0.60 -0.30 0.11 0.34
10641 || orf19.3405 || ZCF18 || || Putative Zn(II)2Cys6 transcription factor; heterozygous null mutant displays sensitivity to virgineone and decreased colonization of mouse kidneys || 1 -0.79 -0.92 -0.61 -0.45 -0.16 -0.23 -0.55 -0.59 -0.49 -0.68 -0.00 -0.15 -0.53 -0.44 -0.05 0.28
10642 || orf19.4263 || || || Has domain(s) with predicted nucleotide binding activity || 1 -1.10 -1.34 -0.87 -0.79 -0.64 -0.63 -0.58 -0.53 -1.00 -0.85 -0.17 -0.31 -0.42 -0.36 0.00 0.41
10643 || orf19.4263 || || || Has domain(s) with predicted nucleotide binding activity || 1 -0.69 -0.77 -0.73 -0.32 -0.36 -0.35 -0.54 -0.14 -0.63 -0.52 -0.03 0.06 -0.22 -0.13 0.08 0.37
10644 || orf19.4263 || || || Has domain(s) with predicted nucleotide binding activity || 1 -1.07 -1.14 -1.12 -0.90 -0.44 -0.64 -0.50 -0.34 -0.94 -0.85 0.06 0.14 -0.19 -0.05 0.17 0.31
10645 || orf19.4134 || || || Ortholog(s) have palmitoyltransferase activity, role in protein palmitoylation and plasma membrane localization || 1 -0.70 -0.84 -0.75 -0.34 -0.33 -0.51 -0.32 -0.60 -0.56 -0.64 -0.12 0.15 -0.35 -0.13 0.37 0.20
10646 || orf19.4031 || || || Ortholog(s) have cytoplasm localization || 1 -0.61 -0.61 -0.30 -0.37 -0.27 -0.15 -0.35 -0.33 -0.46 -0.23 -0.13 0.06 -0.17 -0.00 0.38 0.17
10647 || orf19.3869 || || || Protein of unknown function; regulated by Tsa1, Tsa1B in minimal media at 37 degrees C; shows colony morphology-related gene regulation by Ssn6; Spider biofilm induced || 1 -2.76 -2.83 -1.78 -1.89 -0.86 0.21 -1.21 -2.07 -1.88 -2.15 -0.49 0.84 -0.44 -0.32 1.25 -0.16
10648 || orf19.889 || THI20 || || Putative trifunctional enzyme of thiamine biosynthesis, degradation and salvage; Spider biofilm induced || 1 -1.87 -1.10 -1.22 -0.75 -0.64 0.17 -1.25 -1.14 -0.93 -0.86 -0.55 1.15 -0.83 -0.84 0.62 0.47
10649 || orf19.1054 || || || Ortholog(s) have structural constituent of nuclear pore activity || 1 -1.41 -1.49 -1.20 -0.79 -0.45 0.08 -1.20 -0.89 -1.14 -0.34 0.18 0.37 -0.46 -0.90 0.24 0.04
10650 || orf19.4769 || IPT1 || || Inositol phosphoryl transferase; catalyzes the synthesis of the most abundant sphingolipid, mannose-(inositol-P)2-ceramide, M(IP)2C, from MIPC; required for wild-type membrane localization of Cdr1; Spider biofilm induced || 1 -2.06 -2.68 -2.41 -1.37 -1.30 -0.60 -2.60 -1.42 -2.28 -1.40 0.78 1.84 -1.92 -1.80 1.27 0.68
10651 || orf19.2881 || MNN4 || || Regulator of mannosylphosphorylation of N-linked mannans to cell wall proteins; no role in virulence or normal interaction with macrophages; mutant induces inflammatory cytokines in dendritic cells; rat catheter and Spider biofilm induced || 1 -4.13 -4.84 -3.45 -3.82 -1.63 -1.09 -3.15 -3.75 -3.20 -3.33 0.78 1.79 -1.66 -2.28 2.39 1.26
10652 || orf19.2881 || MNN4 || || Regulator of mannosylphosphorylation of N-linked mannans to cell wall proteins; no role in virulence or normal interaction with macrophages; mutant induces inflammatory cytokines in dendritic cells; rat catheter and Spider biofilm induced || 1 -4.57 -4.17 -3.35 -3.14 -1.82 -1.13 -3.19 -4.26 -3.45 -2.89 0.36 1.58 -1.85 -2.11 2.26 1.17
10653 || orf19.2881 || MNN4 || || Regulator of mannosylphosphorylation of N-linked mannans to cell wall proteins; no role in virulence or normal interaction with macrophages; mutant induces inflammatory cytokines in dendritic cells; rat catheter and Spider biofilm induced || 1 -3.65 -3.91 -2.66 -2.64 -2.04 -0.99 -2.74 -3.58 -2.73 -2.81 0.29 1.44 -1.92 -2.31 1.75 1.22
10654 || orf19.2881 || MNN4 || || Regulator of mannosylphosphorylation of N-linked mannans to cell wall proteins; no role in virulence or normal interaction with macrophages; mutant induces inflammatory cytokines in dendritic cells; rat catheter and Spider biofilm induced || 1 -3.57 -3.62 -2.68 -3.03 -1.79 -0.98 -3.10 -3.61 -2.65 -2.63 0.02 1.11 -2.05 -2.52 1.66 1.18
10655 || orf19.384 || || || Ortholog(s) have Golgi apparatus, cytosol, nucleus localization || 1 -1.12 -1.19 -0.90 -0.84 -0.08 -0.21 -0.61 -0.66 -0.50 -0.69 0.42 0.48 -0.56 -0.37 0.40 0.69
10656 || orf19.5805 || DLD1 || || Putative D-lactate dehydrogenase; white cell-specific trancript; colony morphology-related gene regulation by Ssn6; Hap43-repressed; rat catheter biofilm induced; Spider biofilm repressed || 1 -1.37 -1.44 -1.74 -1.38 -0.85 -0.51 -0.52 -0.96 -0.59 -0.85 0.22 0.65 -1.19 -0.41 0.61 0.49
10657 || orf19.6237 || RAC1 || || G-protein of RAC subfamily; required for embedded filamentous growth, not for serum-induced hyphal growth; dynamic localization at plasma membrane and nucleus; similar to, but not interchangeable with, Cdc42p; lacks S. cerevisiae homolog || 1 -0.83 -0.94 -1.04 -0.79 -1.05 -0.70 -0.82 -0.56 -0.73 -0.28 0.36 0.70 -0.74 -0.29 0.41 0.30
10658 || orf19.6237 || RAC1 || || G-protein of RAC subfamily; required for embedded filamentous growth, not for serum-induced hyphal growth; dynamic localization at plasma membrane and nucleus; similar to, but not interchangeable with, Cdc42p; lacks S. cerevisiae homolog || 1 -1.07 -1.09 -1.11 -0.93 -1.08 -0.86 -0.94 -0.60 -0.79 -0.22 0.46 0.68 -0.80 -0.38 0.24 0.31
10659 || orf19.4769 || IPT1 || || Inositol phosphoryl transferase; catalyzes the synthesis of the most abundant sphingolipid, mannose-(inositol-P)2-ceramide, M(IP)2C, from MIPC; required for wild-type membrane localization of Cdr1; Spider biofilm induced || 1 -3.56 -3.18 -2.99 -5.05 -2.80 -1.80 -2.15 -2.20 -4.34 -1.16 -0.17 1.70 -3.30 -2.22 0.75 1.29
10660 || orf19.4679 || AGP2 || || Amino acid permease; hyphal repressed; white-opaque switch regulated; induced in core caspofungin response, during cell wall regeneration, by flucytosine; regulated by Sef1, Sfu1, and Hap43; rat catheter and Spider biofilm induced || 1 -2.07 -2.40 -1.78 -2.41 -0.64 -0.25 -1.90 -1.98 -1.34 -1.57 0.94 1.28 -2.11 -3.45 0.07 0.54
10661 || orf19.4679 || AGP2 || || Amino acid permease; hyphal repressed; white-opaque switch regulated; induced in core caspofungin response, during cell wall regeneration, by flucytosine; regulated by Sef1, Sfu1, and Hap43; rat catheter and Spider biofilm induced || 1 -4.57 -4.60 -3.48 -5.03 -1.26 -0.27 -3.20 -3.12 -2.42 -2.35 1.02 0.99 -5.42 -5.59 0.23 0.76
10662 || orf19.2969 || RAD16 || || Ortholog of S. cerevisiae Rad16; a protein that recognizes and binds damaged DNA; flucytosine induced; rat catheter and Spider biofilm induced || 1 -1.12 -1.02 -1.19 -1.54 -0.04 0.47 -0.64 -0.85 -0.72 -0.90 0.26 0.26 -1.15 -1.84 0.10 0.44
10663 || orf19.7522 || || || Protein with a pyridoxal phosphate-dependent transferase domain; Hap43-repressed; mutation confers hypersensitivity to amphotericin B; Spider biofilm repressed || 1 -0.71 -0.83 -1.61 -1.20 -0.32 0.28 -1.09 -0.88 -1.25 -1.55 0.77 0.65 -1.35 -1.28 0.40 1.11
10664 || orf19.2179 || SIT1 || || Transporter of ferrichrome siderophores, not ferrioxamine B; required for human epithelial cell invasion in vitro, not for mouse systemic infection; regulated by iron, Sfu1, Rfg1, Tup1, Hap43; rat catheter and Spider biofilm induced || 1 -1.79 -1.70 -2.36 -2.19 -0.92 -0.06 -1.38 -2.18 -2.12 -2.57 0.43 0.17 -1.86 -2.01 0.72 1.69
10665 || orf19.2179 || SIT1 || || Transporter of ferrichrome siderophores, not ferrioxamine B; required for human epithelial cell invasion in vitro, not for mouse systemic infection; regulated by iron, Sfu1, Rfg1, Tup1, Hap43; rat catheter and Spider biofilm induced || 1 -1.62 -1.91 -1.71 -2.14 -0.95 -0.29 -1.84 -2.08 -2.46 -1.89 0.12 -0.35 -1.85 -2.01 -0.25 1.35
10666 || orf19.7522 || || || Protein with a pyridoxal phosphate-dependent transferase domain; Hap43-repressed; mutation confers hypersensitivity to amphotericin B; Spider biofilm repressed || 1 -1.05 -1.24 -1.24 -0.94 -0.63 0.03 -1.46 -1.38 -1.54 -1.55 0.30 0.18 -1.58 -2.02 -0.17 0.67
10667 || orf19.7522 || || || Protein with a pyridoxal phosphate-dependent transferase domain; Hap43-repressed; mutation confers hypersensitivity to amphotericin B; Spider biofilm repressed || 1 -0.92 -0.93 -0.77 -0.56 -0.64 0.05 -1.23 -1.02 -1.38 -1.74 0.15 0.50 -1.55 -1.71 -0.03 1.03
10668 || orf19.6868 || || || Putative NADPH-dependent methylglyoxal reductase; homozygous transposon insertion causes decreased colony wrinkling under filamentous growth-inducing conditions, but does not block true hyphal formation in liquid media || 1 -0.21 -0.30 -0.58 -0.41 -0.31 -0.32 -0.68 -0.39 -0.67 -0.70 0.07 0.10 -0.80 -0.51 0.19 0.48
10669 || orf19.1564 || || || Plasma membrane-localized protein of unknown function || 1 -1.34 -1.41 -1.02 -0.88 -0.80 -0.44 -2.08 -1.83 -1.64 -1.33 -0.08 0.22 -1.70 -1.85 0.29 -0.40
10670 || orf19.199 || || || Protein of unknown function; hyphal-induced expression; upregulated in a cyr1 null mutant || 1 -0.67 -0.88 -0.95 -0.63 -0.12 0.08 -0.91 -1.23 -0.64 -0.40 -0.28 0.25 -0.81 -0.53 0.49 0.00
10671 || orf19.85 || GPX2 || || Similar to glutathione peroxidase; induced in high iron; alkaline induced by Rim101; induced by alpha factor or interaction with macrophage; regulated by Efg1; caspofungin repressed; Spider biofilm induced || 1 -2.73 -3.04 -2.30 -2.04 -2.42 0.29 -3.88 -4.11 -3.00 -2.07 -1.72 0.86 -2.99 -2.73 2.31 1.52
10672 || orf19.85 || GPX2 || || Similar to glutathione peroxidase; induced in high iron; alkaline induced by Rim101; induced by alpha factor or interaction with macrophage; regulated by Efg1; caspofungin repressed; Spider biofilm induced || 1 -3.00 -3.08 -2.58 -1.85 -2.82 0.44 -4.76 -4.16 -2.55 -2.10 -1.86 0.89 -3.07 -2.89 2.29 1.30
10673 || orf19.4565 || BGL2 || || Cell wall 1,3-beta-glucosyltransferase; mutant has cell-wall and growth defects, but wild-type 1,3- or 1,6-beta-glucan content; antigenic; virulence role in mouse systemic infection; rat catheter biofilm induced || 1 -0.56 -0.56 -0.59 -0.30 -0.46 -0.07 -0.43 -0.64 -0.69 -0.66 -0.43 0.06 -0.51 -0.44 0.19 0.20
10674 || orf19.4769 || IPT1 || || Inositol phosphoryl transferase; catalyzes the synthesis of the most abundant sphingolipid, mannose-(inositol-P)2-ceramide, M(IP)2C, from MIPC; required for wild-type membrane localization of Cdr1; Spider biofilm induced || 1 -1.70 -1.50 -1.00 -1.83 -1.21 -1.35 -1.55 -1.65 -1.28 -1.09 -0.18 1.52 -1.72 -2.87 1.07 0.86
10675 || orf19.136 || || || Predicted membrane transporter, member of the drug:proton antiporter (12 spanner) (DHA1) family, major facilitator superfamily (MFS); Hap43p-repressed gene || 1 -1.52 -1.37 -1.27 -1.29 -0.13 0.17 -0.22 -1.51 -1.05 -1.80 -0.58 -0.24 -1.34 -1.36 -0.26 1.05
10676 || orf19.136 || || || Predicted membrane transporter, member of the drug:proton antiporter (12 spanner) (DHA1) family, major facilitator superfamily (MFS); Hap43p-repressed gene || 1 -1.17 -1.63 -0.79 -1.24 -0.08 0.45 -0.27 -1.38 -0.91 -1.26 -0.49 0.16 -1.48 -0.74 -0.19 1.01
10677 || orf19.136 || || || Predicted membrane transporter, member of the drug:proton antiporter (12 spanner) (DHA1) family, major facilitator superfamily (MFS); Hap43p-repressed gene || 1 -1.14 -1.18 -0.71 -0.70 0.06 0.63 -0.23 -1.40 -0.61 -1.60 -0.27 0.10 -1.31 -0.60 -0.13 1.26
10678 || orf19.136 || || || Predicted membrane transporter, member of the drug:proton antiporter (12 spanner) (DHA1) family, major facilitator superfamily (MFS); Hap43p-repressed gene || 1 -0.45 -0.62 -0.31 -0.37 0.05 0.35 -0.38 -0.86 -0.66 -1.25 -0.27 0.33 -0.86 -0.78 -0.05 1.11
10679 || orf19.2099 || HIR1 || || Component of the HIR complex, a nucleosome assembly factor involved in chromatin formation; involved in regulation of white-opaque switching frequency || 1 -0.27 -0.43 -0.02 -0.29 0.32 0.15 -0.61 -0.63 -0.57 -0.69 -0.06 0.14 -0.57 -0.56 -0.30 0.72
10680 || orf19.4690 || || || NRAMP metal ion transporter domain-containing protein; induced by nitric oxide independent of Yhb1; flow model biofilm induced; rat catheter biofilm repressed || 1 -1.30 -1.84 -0.66 -1.36 1.30 0.03 -1.54 -2.03 -1.25 -1.73 -1.08 0.75 -1.08 -0.35 0.02 1.52
10681 || orf19.4690 || || || NRAMP metal ion transporter domain-containing protein; induced by nitric oxide independent of Yhb1; flow model biofilm induced; rat catheter biofilm repressed || 1 -2.28 -2.04 -1.05 -1.01 0.77 -0.03 -2.20 -2.78 -2.57 -2.84 -1.72 0.02 -1.33 -0.54 -0.53 1.05
10682 || orf19.1567 || || || Ortholog(s) have Rab guanyl-nucleotide exchange factor activity, phosphatidylinositol binding activity || 1 -0.34 -0.33 -0.25 -0.42 0.39 0.39 -0.19 -0.19 -0.47 -0.54 0.10 0.44 -0.04 0.12 0.33 0.43
10683 || orf19.2653 || || || Protein with a transient receptor potential (TRP) ion channel domain; mutants are viable; rat catheter and Spider biofilm induced; flow model biofilm repressed || 1 -0.54 -0.51 -0.62 -0.98 1.08 1.46 -0.59 -0.97 -0.95 -0.75 0.39 0.83 -0.63 0.13 0.38 0.86
10684 || orf19.7529 || EPL1 || || Subunit of the NuA4 histone acetyltransferase complex || 1 -0.27 -0.23 -0.35 -0.49 0.49 0.37 -0.14 -0.22 -0.08 -0.52 0.41 0.07 -0.09 0.03 0.17 0.35
10685 || orf19.3315 || CTA9 || || Protein required for normal filamentous growth; induced during the mating process; mRNA binds She3; activates transcription in 1-hybrid assay in S. cerevisiae || 1 -0.48 -0.23 -0.73 -0.99 0.79 0.54 -0.53 -0.34 -0.54 -0.76 0.27 0.16 -0.10 -0.34 0.01 0.32
10686 || orf19.2047 || || || Putative protein of unknown function; Hap43p-repressed gene; mutation confers hypersensitivity to toxic ergosterol analog, and to amphotericin B || 1 -0.67 -0.55 -0.84 -0.88 1.00 1.26 -0.66 -0.67 -0.50 -1.68 0.22 0.18 -0.45 -0.79 0.30 0.56
10687 || orf19.7086 || || || Ortholog(s) have protein transporter activity, role in transcription factor import into nucleus and cytosol, nuclear envelope localization || 1 -0.53 -0.49 -0.39 -0.51 0.39 0.85 -0.45 -0.68 -0.56 -0.64 -0.27 0.03 -0.57 -0.16 0.15 0.67
10688 || orf19.6874 || || || Putative helix-loop-helix (HLH) transcription factor with a role in filamentous growth || 1 -1.41 -1.26 -0.66 -0.98 0.66 1.33 -0.83 -1.09 -1.18 -0.95 0.13 0.13 -0.32 -0.72 0.07 1.13
10689 || orf19.5245 || BUL4 || || Protein with a predicted BUL1 N-terminal and C-terminal domains; Bul1 binds the ubiquitin ligase Rsp5 in S. cerevisiae; Hap43-repressed gene; rat catheter biofilm induced || 1 -1.34 -1.06 -0.55 -0.77 1.15 1.41 -0.25 -1.00 -0.29 -1.34 -0.21 0.08 -1.21 -0.45 1.06 0.75
10690 || orf19.5245 || BUL4 || || Protein with a predicted BUL1 N-terminal and C-terminal domains; Bul1 binds the ubiquitin ligase Rsp5 in S. cerevisiae; Hap43-repressed gene; rat catheter biofilm induced || 1 -1.13 -0.84 0.11 -0.84 1.18 1.40 -0.13 -0.50 -0.25 -0.73 -0.15 0.47 -0.90 -0.18 0.88 0.88
10691 || orf19.4778 || LYS142 || || Zn(II)2Cys6 transcription factor; has similarity to S. cerevisiae Lys14, involved in the regulation of lysine biosynthesis genes; fungal-specific || 1 -0.55 -0.55 -0.28 -0.60 0.56 0.46 -0.19 -0.32 0.11 -0.61 0.12 0.44 -0.56 -0.02 0.09 0.55
10692 || orf19.5148 || CYR1 || || Class III adenylyl cyclase; mutant lacks cAMP; mutant hyphal growth defect rescued by exogenous cAMP; required for mouse mucosal or systemic infection; role in macrophage sensitivity, apoptosis; downstream of Ras1p and CO2 signaling || 1 -0.65 -0.50 -0.15 -0.22 0.55 0.56 -0.32 -0.44 -0.10 -0.29 -0.17 0.50 -0.26 0.26 0.29 0.51
10693 || orf19.5417 || DOT5 || || Putative nuclear thiol peroxidase; alkaline downregulated; sumoylation target; Spider and flow model biofilm induced || 1 -0.40 -0.47 -0.32 -0.60 1.53 1.95 -0.31 -1.37 -0.43 -1.31 -0.49 0.15 -0.26 -0.23 1.40 0.00
10694 || orf19.5417 || DOT5 || || Putative nuclear thiol peroxidase; alkaline downregulated; sumoylation target; Spider and flow model biofilm induced || 1 -0.41 -0.44 -0.08 -0.47 1.57 2.03 -0.32 -1.55 -0.44 -1.36 -0.46 0.50 -0.38 -0.22 1.43 0.37
10695 || orf19.1816 || ALS3 || || Cell wall adhesin; epithelial adhesion, endothelial invasion; alleles vary in adhesiveness; immunoprotective in mice; binds SspB adhesin of S. gordonii in mixed biofilm; induced in/required for Spider biofilm; flow model biofilm repressed || 1 -0.40 -0.17 -0.24 -0.34 0.87 1.24 -0.79 -1.32 -0.53 -1.36 -0.06 0.35 0.13 0.06 0.49 0.34
10696 || orf19.4752 || MSN4 || || Zinc finger transcription factor; similar to S. cerevisiae Msn4, but not a significant stress response regulator in C. albicans; partly complements STRE-activation defect of S. cerevisiae msn2 msn4 double mutant; flow model biofilm induced || 1 -0.38 -0.38 -0.22 -0.73 0.69 1.41 -0.51 -0.85 -0.60 -1.30 -0.29 -0.13 0.37 -0.54 0.78 0.58
10697 || orf19.7550 || IFA14 || || Putative LPF family protein; Plc1-regulated; induced by alpha pheromone in SpiderM medium || 1 -0.24 -0.24 -0.95 -0.94 0.86 1.48 -0.69 -0.79 -0.44 -1.29 -0.43 -0.08 0.05 -0.58 0.59 0.59
10698 || orf19.5158 || || || Protein with similarity to a human gene associated with colon cancer and to orf19.5158; regulated by Gcn4, Cyr1; induced by amino acid starvation; macrophage-induced protein, macrophage-repressed; Spider biofilm induced || 1 -0.52 -0.50 -0.46 -1.25 1.75 1.92 -0.54 -0.46 -0.34 -1.23 -0.40 -0.29 -0.74 -1.12 1.12 -0.87
10699 || orf19.5158 || || || Protein with similarity to a human gene associated with colon cancer and to orf19.5158; regulated by Gcn4, Cyr1; induced by amino acid starvation; macrophage-induced protein, macrophage-repressed; Spider biofilm induced || 1 -0.73 -0.73 -0.86 -1.29 1.45 1.85 -0.61 -0.50 -0.52 -1.14 -0.53 -0.04 -0.82 -0.52 1.12 -0.54
10700 || orf19.5686 || || || Protein of unknown function; Spider biofilm induced || 1 -1.17 -1.36 -0.08 -0.27 1.21 2.29 -0.70 -1.09 -0.12 -1.82 -0.45 0.02 -0.90 -1.03 1.21 -0.44
10701 || orf19.5683 || || || Putative integral membrane protein of unknown function; clade-associated gene expression; Spider biofilm induced || 1 -0.63 -0.72 0.08 -0.46 0.80 1.34 -0.65 -0.82 -0.57 -1.12 -0.44 -0.28 -0.75 -0.47 0.37 -0.61
10702 || orf19.2973 || || || Ortholog(s) have RNA binding, flap-structured DNA binding activity and role in nuclear-transcribed mRNA poly(A) tail shortening, positive regulation of endodeoxyribonuclease activity || 1 -0.31 -0.28 0.05 -0.48 0.77 1.12 -0.74 -0.84 -0.44 -0.64 0.12 -0.18 -0.27 -0.34 0.26 -0.14
10703 || orf19.1816 || ALS3 || || Cell wall adhesin; epithelial adhesion, endothelial invasion; alleles vary in adhesiveness; immunoprotective in mice; binds SspB adhesin of S. gordonii in mixed biofilm; induced in/required for Spider biofilm; flow model biofilm repressed || 1 -0.85 -0.49 -0.66 -1.10 1.27 1.13 -1.62 -1.55 -0.77 -1.28 -0.41 0.15 -0.35 -0.17 0.20 -0.12
10704 || orf19.1816 || ALS3 || || Cell wall adhesin; epithelial adhesion, endothelial invasion; alleles vary in adhesiveness; immunoprotective in mice; binds SspB adhesin of S. gordonii in mixed biofilm; induced in/required for Spider biofilm; flow model biofilm repressed || 1 -1.08 -1.00 -1.27 -1.64 1.15 1.25 -1.72 -1.86 -0.93 -1.62 -0.04 0.08 -0.52 -0.25 0.71 0.43
10705 || orf19.5736 || ALS5 || || ALS family adhesin; highly variable; expression in S. cerevisiae causes adhesion to human epithelium, endothelium or ECM, endothelial invasiveness by endocytosis and, at high abundance, ECM-induced aggregation; can form amyloid fibrils || 1 -0.41 -0.42 -0.64 -0.83 0.65 0.69 -0.92 -1.30 -0.62 -0.52 -0.15 0.40 -0.56 -0.35 0.48 0.06
10706 || orf19.2653 || || || Protein with a transient receptor potential (TRP) ion channel domain; mutants are viable; rat catheter and Spider biofilm induced; flow model biofilm repressed || 1 -0.90 -0.78 -1.38 -1.21 0.96 0.94 -0.93 -1.19 -1.19 -1.10 0.25 0.35 -0.52 -0.20 0.73 0.00
10707 || orf19.699 || || || Protein of unknown function; flow model, rat catheter, Spider biofilm induced || 1 -2.15 -1.63 -2.90 -2.15 2.62 2.54 -1.57 -2.36 -1.40 -2.83 -0.22 -1.22 -1.25 -1.32 1.94 0.55
10708 || orf19.6759 || || || Protein of unknown function || 1 -0.53 -0.49 -0.68 -0.88 0.62 0.55 -0.60 -0.70 -0.71 -0.66 -0.36 0.01 -0.47 -0.42 0.47 -0.39
10709 || orf19.5686 || || || Protein of unknown function; Spider biofilm induced || 1 -2.29 -2.19 -1.45 -1.63 1.57 2.30 -1.68 -2.12 -0.93 -2.49 -0.85 -0.12 -1.74 -1.42 1.57 -0.73
10710 || orf19.882 || HSP78 || || Heat-shock protein; regulated by macrophage response, Nrg1, Mig1, Gcn2, Gcn4, Mnl1p; heavy metal (cadmium) stress-induced; stationary phase enriched protein; rat catheter and Spider biofilm induced || 1 -1.33 -1.63 -1.37 -1.75 1.61 2.57 -1.78 -2.33 -1.60 -2.18 -1.50 -0.61 -1.93 -1.44 1.76 -0.65
10711 || orf19.882 || HSP78 || || Heat-shock protein; regulated by macrophage response, Nrg1, Mig1, Gcn2, Gcn4, Mnl1p; heavy metal (cadmium) stress-induced; stationary phase enriched protein; rat catheter and Spider biofilm induced || 1 -1.85 -1.86 -1.89 -2.70 1.62 2.61 -2.23 -2.79 -2.03 -2.46 -1.71 -1.19 -1.96 -1.84 1.52 -0.75
10712 || orf19.2691 || || || Planktonic growth-induced gene || 1 -1.76 -1.92 -1.75 -2.18 1.89 1.98 -1.82 -2.13 -1.97 -2.56 -0.86 -0.75 -1.14 -1.82 0.69 -0.03
10713 || orf19.2691 || || || Planktonic growth-induced gene || 1 -1.71 -1.70 -1.30 -1.66 1.93 2.05 -1.42 -1.60 -1.65 -2.22 -0.56 -0.51 -0.68 -1.60 0.87 0.03
10714 || orf19.4816 || || || Protein of unknown function; induced by nitric oxide || 1 -1.47 -1.45 -1.09 -1.36 1.58 2.10 -1.43 -1.48 -0.91 -1.29 -0.65 0.05 -1.50 -0.68 1.32 0.23
10715 || orf19.6492 || || || Predicted protein serine/threonine kinase and/or protein tyrosine kinase; Spider biofilm induced || 1 -0.88 -0.88 -0.52 -0.48 1.07 1.61 -0.83 -1.37 -0.92 -1.66 -0.29 0.04 -0.76 -0.53 1.10 0.78
10716 || orf19.6492 || || || Predicted protein serine/threonine kinase and/or protein tyrosine kinase; Spider biofilm induced || 1 -1.30 -1.00 -0.98 -0.72 1.16 1.66 -1.33 -1.76 -0.83 -1.79 -0.77 0.11 -0.73 -1.09 1.10 0.40
10717 || orf19.6492 || || || Predicted protein serine/threonine kinase and/or protein tyrosine kinase; Spider biofilm induced || 1 -1.36 -1.28 -0.87 -0.29 1.23 1.98 -1.69 -1.68 -1.24 -1.21 -0.88 -0.19 -1.26 -0.79 0.89 0.22
10718 || orf19.1331 || HSM3 || || Ortholog(s) have role in mismatch repair, proteasome regulatory particle assembly and cytosol, nucleus, proteasome regulatory particle, base subcomplex localization || 1 -1.04 -1.07 -0.77 -0.68 0.59 1.20 -1.62 -1.92 -1.11 -1.33 -0.65 -0.32 -1.05 -0.27 1.28 0.37
10719 || orf19.2014 || BCY1 || || Protein kinase A regulatory subunit; required for nuclear localization of Tpk1; physically interacts with Tpk1; essential; apoptosis-regulated; bcy1 heterozygous or bcy1 tpk2 mutant has filamentous growth defect || 1 -0.37 -0.63 -0.38 -0.47 0.49 0.37 -0.70 -0.54 -0.56 -0.68 -0.11 0.03 -0.59 -0.24 0.47 0.36
10720 || orf19.1974 || TFS1 || || Putative carboxypeptidase y inhibitor; transcript regulated upon yeast-hypha switch; colony morphology-related gene regulation by Ssn6 || 1 -0.38 -0.28 -0.46 -0.73 1.05 1.50 -0.50 -0.97 -0.64 -1.90 -0.16 0.20 -0.62 -0.98 1.23 0.11
10721 || orf19.1974 || TFS1 || || Putative carboxypeptidase y inhibitor; transcript regulated upon yeast-hypha switch; colony morphology-related gene regulation by Ssn6 || 1 -0.62 -0.68 -0.54 -0.76 1.13 1.49 -0.42 -0.97 -0.68 -1.81 0.09 0.39 -0.50 -1.13 1.34 0.09
10722 || orf19.4907 || || || Putative protein of unknown function; Hap43p-repressed gene; increased transcription is observed upon fluphenazine treatment; possibly transcriptionally regulated by Tac1p; induced by nitric oxide; fungal-specific (no human/murine homolog || 1 -1.00 -0.93 -0.74 -1.12 1.32 2.22 -1.32 -1.34 -1.25 -2.43 0.04 -0.14 -1.10 -2.26 1.00 0.31
10723 || orf19.4907 || || || Putative protein of unknown function; Hap43p-repressed gene; increased transcription is observed upon fluphenazine treatment; possibly transcriptionally regulated by Tac1p; induced by nitric oxide; fungal-specific (no human/murine homolog || 1 -0.87 -0.88 -0.51 -0.93 1.22 2.44 -1.11 -0.85 -1.24 -2.12 -0.17 -0.08 -0.61 -2.07 1.04 0.52
10724 || orf19.7567 || || || Protein of unknown function; induced by alpha pheromone in SpiderM medium || 1 -0.69 -0.79 -0.96 -1.35 2.18 2.18 -1.23 -1.37 -1.06 -1.93 -0.92 -0.46 -1.20 -1.50 0.87 0.47
10725 || orf19.2414 || || || Ortholog of S. cerevisiae Mpm1; a mitochondrial intermembrane space protein of unknown function; Hap43-repressed; Spider biofilm induced || 1 -0.74 -0.54 -1.02 -1.73 1.42 1.48 -0.75 -1.45 -0.62 -1.72 -0.54 -0.60 -1.24 -1.13 1.21 0.17
10726 || orf19.2414 || || || Ortholog of S. cerevisiae Mpm1; a mitochondrial intermembrane space protein of unknown function; Hap43-repressed; Spider biofilm induced || 1 -0.33 -0.48 -0.69 -1.45 1.79 1.72 -0.72 -1.22 -0.18 -1.57 -0.31 -0.48 -0.89 -0.93 1.25 0.53
10727 || orf19.699 || || || Protein of unknown function; flow model, rat catheter, Spider biofilm induced || 1 -0.54 -0.29 -0.86 -1.27 2.05 2.54 -0.70 -0.77 -1.18 -1.53 -0.32 -0.63 -0.95 -1.06 1.85 0.63
10728 || orf19.4980 || HSP70 || || Putative hsp70 chaperone; role in entry into host cells; heat-shock, amphotericin B, cadmium, ketoconazole-induced; surface localized in yeast and hyphae; antigenic in host; farnesol-downregulated in biofilm; Spider biofilm induced || 1 -1.35 -1.48 -1.71 -1.95 1.60 2.44 -1.52 -1.40 -1.00 -0.82 -0.56 0.29 -0.42 -1.02 2.04 -0.44
10729 || orf19.4980 || HSP70 || || Putative hsp70 chaperone; role in entry into host cells; heat-shock, amphotericin B, cadmium, ketoconazole-induced; surface localized in yeast and hyphae; antigenic in host; farnesol-downregulated in biofilm; Spider biofilm induced || 1 -1.19 -1.26 -1.38 -1.21 1.39 -1.51 -1.17 -1.05 -0.92 -0.41 0.29 -0.68 -1.32 1.70 -0.47
10730 || orf19.699 || || || Protein of unknown function; flow model, rat catheter, Spider biofilm induced || 1 -2.33 -1.87 -1.94 -2.18 2.68 2.54 -1.66 -2.20 -3.61 -1.72 -0.49 -0.98 -1.41 -2.98 2.39 0.94
10731 || orf19.3635 || || || Ortholog of C. dubliniensis CD36 : Cd36_22580, C. parapsilosis CDC317 : CPAR2_406960, Candida tenuis NRRL Y-1498 : CANTEDRAFT_113677 and Debaryomyces hansenii CBS767 : DEHA2D03608g || 1 -0.49 -0.26 -0.58 -0.50 0.84 0.77 -0.83 -0.52 -0.97 -0.50 -0.21 0.37 -0.71 -0.89 0.76 -0.36
10732 || orf19.891 || || || Putative AMP deaminase; possibly an essential gene, disruptants not obtained by UAU1 method || 1 -0.55 -0.57 -0.62 -0.54 0.76 1.34 -0.93 -1.00 -1.03 -0.46 0.12 0.67 -0.90 -0.89 0.84 -0.03
10733 || orf19.891 || || || Putative AMP deaminase; possibly an essential gene, disruptants not obtained by UAU1 method || 1 -0.37 -0.32 -0.63 -0.65 1.16 1.37 -1.02 -0.96 -0.86 -0.44 0.32 0.47 -0.53 -0.94 0.98 -0.28
10734 || orf19.2268 || RCK2 || || Predicted MAP kinase-activated protein kinase, similar to S. cerevisiae serine/threonine protein kinase Rck2p; induced by osmotic stress via Hog1p; macrophage/pseudohyphal-repressed; mutants are sensitive to rapamycin || 1 -0.39 -0.16 -0.60 -0.52 0.98 1.48 -0.43 -0.57 -0.44 -0.47 0.22 0.46 -0.66 -0.61 1.00 -0.02
10735 || orf19.2973 || || || Ortholog(s) have RNA binding, flap-structured DNA binding activity and role in nuclear-transcribed mRNA poly(A) tail shortening, positive regulation of endodeoxyribonuclease activity || 1 -0.31 -0.30 -0.38 -0.92 0.87 1.14 -0.50 -0.81 -0.70 -0.43 0.24 0.24 -0.32 -0.28 0.64 0.04
10736 || orf19.246 || || || Predicted metalloendopeptidase; Spider biofilm induced || 1 -1.01 -0.97 -0.28 -0.94 1.18 1.69 -1.27 -1.73 -2.03 -1.07 0.15 0.42 -1.13 -0.70 0.78 -0.24
10737 || orf19.7567 || || || Protein of unknown function; induced by alpha pheromone in SpiderM medium || 1 -0.62 -0.75 -0.71 -0.74 1.68 2.49 -0.71 -1.26 -1.27 -0.93 -0.64 -0.13 -0.51 -1.19 0.67 0.45
10738 || orf19.1656 || || || Protein with a predicted FYVE/PHD zinc finger domain; Hap43-repressed; Spider biofilm induced || 1 -0.36 -0.63 -0.48 -0.25 1.23 1.69 -0.61 -0.82 -0.65 -0.85 -0.50 -0.02 -0.55 -1.46 0.62 -0.41
10739 || orf19.6387 || HSP104 || || Heat-shock protein; roles in biofilm and virulence; complements chaperone, prion activity in S. cerevisiae; guanidine-insensitive; heat shock/stress induced; repressed in farnesol-treated biofilm; sumoylation target; Spider biofilm induced || 1 -0.31 -0.24 0.18 -0.29 1.12 2.09 -1.18 -1.30 -1.19 -1.95 -0.77 -0.21 -0.59 -0.88 1.21 -0.07
10740 || orf19.6387 || HSP104 || || Heat-shock protein; roles in biofilm and virulence; complements chaperone, prion activity in S. cerevisiae; guanidine-insensitive; heat shock/stress induced; repressed in farnesol-treated biofilm; sumoylation target; Spider biofilm induced || 1 -0.42 -0.41 0.18 -0.47 1.10 2.02 -1.31 -1.76 -1.12 -1.80 -0.83 0.09 -0.36 -0.58 1.21 -0.38
10741 || orf19.6387 || HSP104 || || Heat-shock protein; roles in biofilm and virulence; complements chaperone, prion activity in S. cerevisiae; guanidine-insensitive; heat shock/stress induced; repressed in farnesol-treated biofilm; sumoylation target; Spider biofilm induced || 1 -0.41 -0.52 -0.17 -0.54 0.95 1.87 -1.51 -1.88 -1.13 -1.85 -0.98 -0.17 -0.57 -0.77 1.37 0.10
10742 || orf19.6387 || HSP104 || || Heat-shock protein; roles in biofilm and virulence; complements chaperone, prion activity in S. cerevisiae; guanidine-insensitive; heat shock/stress induced; repressed in farnesol-treated biofilm; sumoylation target; Spider biofilm induced || 1 -0.47 -0.48 -0.40 -0.70 1.02 1.81 -1.51 -2.13 -1.42 -2.04 -0.98 -0.36 -0.70 -0.95 1.38 -0.15
10743 || orf19.6387 || HSP104 || || Heat-shock protein; roles in biofilm and virulence; complements chaperone, prion activity in S. cerevisiae; guanidine-insensitive; heat shock/stress induced; repressed in farnesol-treated biofilm; sumoylation target; Spider biofilm induced || 1 -0.57 -0.55 -0.40 -0.94 1.12 2.05 -1.42 -2.05 -1.34 -2.31 -0.94 -0.35 -0.62 -0.77 1.44 -0.34
10744 || orf19.1461 || || || S. pombe ortholog SPCC576.01c is a predicted sulfonate dioxygenase; possibly transcriptionally regulated upon hyphal formation; Spider biofilm induced || 1 -0.38 -0.27 -0.31 -0.35 0.65 0.81 -0.66 -1.26 -0.46 -1.10 -0.41 -0.28 -0.34 -0.37 1.16 0.22
10745 || orf19.1331 || HSM3 || || Ortholog(s) have role in mismatch repair, proteasome regulatory particle assembly and cytosol, nucleus, proteasome regulatory particle, base subcomplex localization || 1 -0.24 -0.35 -0.00 -0.22 0.65 1.33 -1.01 -1.20 -0.64 -0.99 -0.44 0.01 -0.32 0.10 1.19 0.30
10746 || orf19.4347 || || || Putative serine/threonine protein kinase; Hog1p-induced || 1 -0.54 -0.56 -0.15 -0.08 0.82 1.27 -0.90 -1.28 -0.80 -0.89 -0.47 -0.22 -0.63 0.09 0.60 0.08
10747 || orf19.5953 || || || C2H2 transcription factor; predicted regulator of ribosomal protein and biogenesis genes; possibly essential, disruptants not obtained by UAU1 method; rat catheter biofilm induced || 1 -0.29 -0.52 -0.16 -0.33 1.02 1.06 -0.93 -0.84 -0.47 -0.60 -0.02 0.16 -0.29 -0.52 0.31 0.78
10748 || orf19.7414 || ALS6 || || ALS family protein; expression in S. cerevisiae confers adhesion to gelatin; macrophage-induced gene; N-terminal adhesion domain; ALS family includes cell-surface glycoproteins, some with adhesin function || 1 -0.32 -0.28 -0.27 -0.75 0.90 0.81 -0.63 -1.02 -0.53 -0.29 0.01 0.62 -0.33 -0.89 0.55 0.46
10749 || orf19.84 || CAN3 || || Predicted amino acid transmembrane transporter; transcript regulated by white-opaque switch; Hap43-repressed gene || 1 -0.35 0.06 -0.24 -0.38 0.37 1.16 -0.79 -0.87 -1.16 -1.57 -0.60 0.20 -0.74 -1.33 1.32 1.32
10750 || orf19.6840 || || || Protein of unknown function; transcript detected in high-resolution tiling arrays; transcription induced by alpha pheromone in SpiderM medium; Spider and early-stage flow model biofilm induced || 1 -0.48 -0.35 -0.53 -0.59 -0.09 1.25 -0.84 -1.66 -1.47 -2.15 -0.51 0.65 -0.88 -1.77 2.07 0.15
10751 || orf19.5612 || BMT4 || || Beta-mannosyltransferase; for elongation of beta-mannose chains on the acid-labile fraction of cell wall phosphopeptidomannan; 9-gene family member; regulated by Tsa1, Tsa1B; flow model biofilm induced; rat catheter biofilm repressed || 1 -0.16 -0.15 -0.95 -0.84 0.90 1.31 -0.85 -1.51 -1.37 -2.20 0.29 0.01 -0.70 -2.27 1.09 0.65
10752 || orf19.4317 || GRE3 || || Putative D-xylose reductase; antigenic in murine systemic infection; soluble protein in hyphae; induced by farnesol, macrophage interaction and by Mnl1 under weak acid stress; stationary-phase enriched protein; Spider biofilm induced || 1 -0.16 -0.21 -0.38 -0.54 0.74 0.91 -0.17 -0.61 -0.94 -1.36 0.06 0.16 -0.33 -0.76 0.87 -0.18
10753 || orf19.1979 || GIT3 || || Glycerophosphocholine permease; white cell specific transcript; fungal-specific; alkaline repressed; caspofungin, macrophage/pseudohyphal-repressed; flow model biofilm induced; Spider biofilm induced || 1 -0.22 -0.18 -0.95 -0.96 1.42 1.99 -0.09 -0.72 -1.87 -2.68 0.20 0.55 -0.40 -1.78 1.24 -0.09
10754 || orf19.5450 || ETR1 || || Putative 2-enoyl thioester reductase; protein present in exponential and stationary growth phase yeast cultures; rat catheter biofilm repressed || 1 0.09 0.10 -0.14 -0.14 0.36 0.42 -0.17 -0.20 -0.18 -0.64 -0.02 -0.01 0.14 -0.53 0.38 0.07
10755 || orf19.2996 || || || Ortholog(s) have cytoplasm localization || 1 -0.27 -0.39 -0.88 -0.81 -0.21 0.04 -0.28 -0.69 -0.47 -0.58 -0.31 0.23 -0.13 -1.00 0.54 0.09
10756 || orf19.4185 || || || Ortholog(s) have phosphoprotein phosphatase activity, thiosulfate sulfurtransferase activity, role in DNA-dependent DNA replication, protein dephosphorylation, regulation of DNA-dependent DNA replication and cytosol, nucleus localization || 1 -0.29 -0.51 -0.94 -1.08 0.04 0.59 -0.19 0.00 -0.61 -0.89 0.86 0.85 -0.52 -0.51 0.05 1.02
10757 || orf19.4185 || || || Ortholog(s) have phosphoprotein phosphatase activity, thiosulfate sulfurtransferase activity, role in DNA-dependent DNA replication, protein dephosphorylation, regulation of DNA-dependent DNA replication and cytosol, nucleus localization || 1 -0.26 -0.34 -0.70 -0.70 -0.11 0.58 -0.09 -0.08 -0.67 -0.74 0.75 0.64 -0.61 -0.40 0.04 1.10
10758 || orf19.4185 || || || Ortholog(s) have phosphoprotein phosphatase activity, thiosulfate sulfurtransferase activity, role in DNA-dependent DNA replication, protein dephosphorylation, regulation of DNA-dependent DNA replication and cytosol, nucleus localization || 1 -0.58 -0.71 -0.51 -0.88 -0.41 0.61 -0.42 -0.28 -0.60 -0.82 0.89 0.79 -0.80 -0.56 -0.34 1.27
10759 || orf19.4185 || || || Ortholog(s) have phosphoprotein phosphatase activity, thiosulfate sulfurtransferase activity, role in DNA-dependent DNA replication, protein dephosphorylation, regulation of DNA-dependent DNA replication and cytosol, nucleus localization || 1 -0.61 -0.66 -0.97 -1.12 -0.23 0.65 -0.64 -0.15 -0.41 -0.84 0.94 0.56 -0.92 -0.78 -0.33 1.10
10760 || orf19.4185 || || || Ortholog(s) have phosphoprotein phosphatase activity, thiosulfate sulfurtransferase activity, role in DNA-dependent DNA replication, protein dephosphorylation, regulation of DNA-dependent DNA replication and cytosol, nucleus localization || 1 -0.91 -0.70 -0.94 -1.19 -0.43 0.35 -0.47 -0.23 -0.75 -0.87 0.61 0.38 -1.11 -0.39 -0.42 1.02
10761 || orf19.6898 || || || Protein similar to S. pombe SPBC1709.16c a predicted aromatic ring-opening dioxygenase; induced by benomyl treatment or in azole-resistant strain that overexpresses MDR1; Spider biofilm induced || 1 -0.37 -0.76 -0.79 -1.21 0.22 0.18 -0.67 -0.80 -0.77 -1.51 1.00 0.35 -1.44 -1.96 -0.40 0.97
10762 || orf19.3016 || || || Ortholog(s) have role in meiotic chromosome segregation and cytosol, nucleus localization || 1 -0.19 -0.27 -0.82 -0.78 0.76 1.15 -0.36 -0.35 -0.97 -0.74 0.82 0.40 -0.08 -1.60 0.07 0.08
10763 || orf19.6770 || || || protein with ENTH Epsin domain, N-terminal; Spider biofilm repressed || 1 -1.11 -1.20 -1.18 -0.50 0.99 1.20 -0.37 -0.49 -1.05 -0.99 0.91 -0.13 -0.48 -1.59 0.70 0.06
10764 || orf19.6640 || TPS1 || || Trehalose-6-phosphate synthase; role in hyphal growth and virulence in mouse systemic infection; induced in presence of human neutrophils; macrophage/pseudohyphal-repressed after 16h; stationary phase enriched protein; Hap43-repressed || 1 -0.77 -0.75 -0.60 -1.11 0.58 0.90 -0.03 -0.31 0.00 -1.62 0.14 0.27 0.20 -0.51 0.55 0.09
10765 || orf19.1862 || || || Possible stress protein; increased transcription associated with CDR1 and CDR2 overexpression or fluphenazine treatment; regulated by Sfu1, Nrg1, Tup1; stationary phase enriched protein; Spider biofilm induced || 1 -2.95 -3.29 -3.03 -3.73 0.82 0.70 -0.70 -1.44 -1.22 -4.64 2.24 1.65 -0.53 -3.23 1.88 -0.25
10766 || orf19.1862 || || || Possible stress protein; increased transcription associated with CDR1 and CDR2 overexpression or fluphenazine treatment; regulated by Sfu1, Nrg1, Tup1; stationary phase enriched protein; Spider biofilm induced || 1 -2.33 -2.37 -2.56 -2.86 0.56 0.71 -0.47 -1.16 -0.81 -4.08 2.02 1.96 -0.36 -2.57 1.72 -0.06
10767 || orf19.1862 || || || Possible stress protein; increased transcription associated with CDR1 and CDR2 overexpression or fluphenazine treatment; regulated by Sfu1, Nrg1, Tup1; stationary phase enriched protein; Spider biofilm induced || 1 -2.24 -2.48 -2.50 -2.87 0.96 0.73 -0.51 -1.02 -1.14 -4.24 2.16 1.96 -0.48 -3.13 1.77 -0.03
10768 || orf19.1862 || || || Possible stress protein; increased transcription associated with CDR1 and CDR2 overexpression or fluphenazine treatment; regulated by Sfu1, Nrg1, Tup1; stationary phase enriched protein; Spider biofilm induced || 1 -2.24 -2.38 -2.37 -2.91 0.80 0.84 -0.03 -0.68 -0.62 -4.21 2.25 1.89 0.14 -2.79 1.65 -0.03
10769 || orf19.1862 || || || Possible stress protein; increased transcription associated with CDR1 and CDR2 overexpression or fluphenazine treatment; regulated by Sfu1, Nrg1, Tup1; stationary phase enriched protein; Spider biofilm induced || 1 -1.00 -0.91 -1.89 -2.35 0.82 0.72 -0.12 -0.69 -0.95 -3.16 2.16 1.95 0.05 -2.89 1.45 0.05
10770 || orf19.4251 || ZCF22 || || Predicted Zn(II)2Cys6 transcription factor || 1 -0.69 -0.54 -1.17 -0.65 0.41 0.53 -0.27 -0.19 -0.25 -0.83 0.58 1.37 -0.79 -0.81 0.33 0.32
10771 || orf19.2948 || SNO1 || || Protein with a predicted role in pyridoxine metabolism; stationary phase protein; regulated by Tup1, Efg1; Spider biofilm induced || 1 -0.72 -0.80 -1.43 -1.39 -0.07 0.43 0.02 -0.68 0.18 -1.69 0.96 1.15 -1.03 -0.75 1.26 0.68
10772 || orf19.2948 || SNO1 || || Protein with a predicted role in pyridoxine metabolism; stationary phase protein; regulated by Tup1, Efg1; Spider biofilm induced || 1 -0.89 -0.88 -1.42 -1.18 -0.19 0.43 -0.34 -0.92 0.07 -1.75 0.68 1.05 -0.97 -1.12 1.13 0.57
10773 || orf19.2948 || SNO1 || || Protein with a predicted role in pyridoxine metabolism; stationary phase protein; regulated by Tup1, Efg1; Spider biofilm induced || 1 -1.06 -0.55 -0.96 -1.04 0.10 0.57 -0.08 -0.89 0.26 -1.30 0.52 1.21 -0.98 -0.89 1.00 0.55
10774 || orf19.2948 || SNO1 || || Protein with a predicted role in pyridoxine metabolism; stationary phase protein; regulated by Tup1, Efg1; Spider biofilm induced || 1 -0.51 -0.31 -0.68 -0.50 -0.12 0.70 -0.12 -0.51 0.42 -1.70 0.74 1.11 -0.75 -0.95 1.35 0.76
10775 || orf19.2948 || SNO1 || || Protein with a predicted role in pyridoxine metabolism; stationary phase protein; regulated by Tup1, Efg1; Spider biofilm induced || 1 -0.83 0.18 -1.15 -0.82 0.06 1.00 -0.18 -0.72 0.51 -1.36 0.85 1.11 -0.58 -0.52 1.33 0.42
10776 || orf19.6058 || GLO1 || || Putative monomeric glyoxalase I; oxidative stress-induced via Cap1; flow model and rat catheter biofilm repressed || 1 -0.48 -0.87 -0.92 -0.73 0.37 0.35 0.18 0.08 -0.13 -0.60 1.19 0.58 -0.66 -0.57 0.77 0.23
10777 || orf19.3198 || OBPA || || Similar to oxysterol binding protein; non-sex gene located within the MTLa mating-type-like locus; Plc1p-regulated || 1 -0.17 -0.19 -0.23 -0.21 -0.03 0.49 -0.25 -0.12 -0.24 -0.57 0.46 0.76 -0.52 0.04 0.58 0.27
10778 || orf19.1719 || SGA1 || || Putative glucoamylase; induced in oralpharyngeal candidasis; rat catheter and Spider biofilm induced || 1 -0.40 -0.55 -0.64 -0.19 0.40 1.00 -0.58 -0.40 -0.55 -0.38 1.04 1.35 -0.93 -0.37 0.79 0.72
10779 || orf19.6338 || || || Ortholog of Candida albicans WO-1 : CAWG_05352 || 1 -0.74 -0.43 -0.36 0.14 0.34 1.10 -0.28 -0.24 -0.50 -0.73 0.85 0.74 -0.66 -0.52 0.13 0.61
10780 || orf19.4269 || || || Has domain(s) with predicted ATP binding, protein kinase activity and role in protein phosphorylation || 1 -0.68 -0.61 -0.65 -0.51 0.84 0.85 -0.74 -0.32 -0.30 -0.72 0.68 0.98 -0.01 -1.03 0.81 1.10
10781 || orf19.7420 || || || Ortholog(s) have RNA polymerase II transcription coactivator activity involved in preinitiation complex assembly activity || 1 -0.48 -0.15 -0.08 -0.22 0.62 0.49 -0.27 -0.11 -0.64 -0.57 0.70 0.40 -0.11 -0.55 0.54 0.35
10782 || orf19.787 || || || Protein of unknown function || 1 -0.32 -0.22 -0.52 -0.76 0.26 0.74 -0.40 -0.47 -1.43 -1.07 1.28 0.68 -0.53 -1.07 -0.09 1.16
10783 || orf19.4195.1 || FCA1 || || Cytosine deaminase; enzyme of pyrimidine salvage; functional homolog of S. cerevisiae Fcy1p; mutation is associated with resistance to flucytosine (5-FC) in a clinical isolate; hyphal downregulated; gene has intron || 1 -0.25 -0.17 -0.51 -0.77 0.67 1.16 -0.41 -0.33 -1.31 -1.16 1.07 1.14 -0.65 -1.76 0.32 1.49
10784 || orf19.1189 || || || Protein of unknown function; regulated by yeast-hypha switch; induced by Mnl1 in weak acid stress; 5' UTR intron; repressed by chlamydospore formation in C. albicans and C. dubliniensis; rat catheter, Spider and flow model biofilm induced || 1 -1.13 -1.48 -1.59 -2.24 1.15 1.77 -0.84 -1.08 -3.18 -3.05 1.92 1.45 -1.09 -3.13 2.06 1.60
10785 || orf19.2172 || ARA1 || || D-Arabinose dehydrogenase; dehydro-D-arabinono-1,4-lactone synthesis; active on D-arabinose, L-fucose, L-xylose, L-galactose; inhibited by metal ions, thiol group-specific reagents; induced on polystyrene adherence; Spider biofilm induced || 1 -0.61 -0.57 -0.51 -0.44 0.52 0.83 -0.77 -1.04 -1.30 -1.77 1.34 1.50 -0.84 -1.32 1.29 0.60
10786 || orf19.1852 || || || Ortholog(s) have mitochondrion localization || 1 -0.63 -0.86 -0.58 -0.26 0.03 0.63 -0.87 -0.44 -1.04 -1.01 0.73 0.93 -1.01 -1.01 0.76 0.82
10787 || orf19.5474 || || || Protein of unknown function; induced by Mnl1 under weak acid stress; transcript detected on high-resolution tiling arrays; Spider biofilm repressed || 1 -0.86 -0.92 -0.77 -0.67 -0.49 0.66 -0.86 -0.67 -1.02 -0.87 1.15 0.98 -0.44 -1.85 1.55 0.99
10788 || orf19.6053 || CIS2 || || Putative role in regulation of biogenesis of the cell wall; upregulated in biofilm; Gcn4p-regulated || 1 -0.99 -1.00 -0.45 -1.29 -0.44 -0.23 -1.36 -0.84 -0.89 -0.81 1.11 1.17 -0.80 -1.70 1.02 0.68
10789 || orf19.4251 || ZCF22 || || Predicted Zn(II)2Cys6 transcription factor || 1 -0.08 -0.35 -0.59 -0.33 0.03 0.15 -0.28 -0.19 -0.39 -0.92 0.28 0.93 0.05 -0.56 0.06 0.19
10790 || orf19.3743 || || || Ortholog of C. dubliniensis CD36 : Cd36_27230, C. parapsilosis CDC317 : CPAR2_801320, Candida tenuis NRRL Y-1498 : CANTEDRAFT_113198 and Debaryomyces hansenii CBS767 : DEHA2E23782g || 1 -1.02 -1.07 -0.74 -0.58 -0.06 0.43 -0.17 -0.05 0.06 -0.76 0.46 0.32 -0.55 -0.70 0.13 0.50
10791 || orf19.1573 || || || Ortholog(s) have endoplasmic reticulum, fungal-type vacuole membrane localization || 1 -0.63 -0.62 -0.41 -0.12 0.08 0.44 -0.31 0.09 -0.08 -0.23 0.28 0.53 -0.69 -0.52 0.18 0.33
10792 || orf19.6673 || HEX1 || || Beta-N-acetylhexosaminidase/chitobiase, highly glycosylated enzyme that is secreted to the periplasm and culture medium; required for full virulence; may have role in carbon or nitrogen scavenging; possibly an essential gene (UAU1 method) || 1 -0.47 -0.65 -0.56 -0.40 0.32 0.04 -0.03 0.09 0.24 -0.18 0.32 0.53 -0.43 -0.90 0.34 0.43
10793 || orf19.3329 || || || Ortholog(s) have sphingosine-1-phosphate phosphatase activity, role in calcium-mediated signaling and endoplasmic reticulum localization || 1 -1.06 -0.90 -0.64 -0.39 0.07 0.68 -0.63 -0.56 0.21 -0.12 0.05 0.51 -0.78 -0.25 0.20 0.88
10794 || orf19.4187 || || || Ortholog(s) have role in hyphal growth, mitochondrial genome maintenance, phospholipid transport, protein import into mitochondrial outer membrane, sporocarp development involved in sexual reproduction || 1 -0.61 -0.56 -0.70 -0.73 0.07 0.25 -0.57 -0.65 -0.00 0.04 -0.25 0.08 -0.52 -0.15 0.32 0.28
10795 || orf19.3019 || || || Putative DNA-dependent ATPase; transcription may be increased in an azole-resistant strain that overexpresses MDR1 || 1 -0.66 -0.80 -0.52 -0.73 0.39 0.52 -0.20 -0.52 0.02 -0.01 -0.29 -0.13 -0.22 0.08 0.20 0.45
10796 || orf19.2110 || || || Ortholog(s) have arginyltransferase activity, role in protein arginylation and cytosol, nucleus localization || 1 -0.73 -0.90 -0.49 -0.72 -0.16 0.22 -0.57 -0.67 0.12 -0.59 -0.44 0.06 -0.38 0.12 -0.05 0.55
10797 || orf19.5159 || DUG3 || || Putative glutamine amidotransferase (GATase II); role in glutathione catabolism; || 1 -1.01 -0.98 -0.68 -1.13 0.25 0.34 -0.28 -0.55 -0.05 -1.11 0.09 -0.19 -0.73 0.14 0.18 0.78
10798 || orf19.4850 || || || Ortholog(s) have cytosol, nucleus localization || 1 -0.52 -0.35 -0.36 -0.53 0.10 0.56 -0.50 -0.46 -0.16 -0.54 -0.21 -0.02 -0.66 0.19 0.24 0.29
10799 || orf19.4850 || || || Ortholog(s) have cytosol, nucleus localization || 1 -0.46 -0.39 -0.10 -0.34 0.27 0.38 -0.40 -0.32 -0.02 -0.29 -0.08 -0.05 -0.29 0.15 0.26 0.35
10800 || orf19.3047 || || || Protein kinase-related protein, required for normal sensitivity to caspofungin || 1 -1.96 -1.62 -0.76 -1.53 0.38 0.75 -1.24 -1.24 -0.31 -0.84 -0.14 0.43 -1.28 0.18 0.75 0.98
10801 || orf19.3402 || FPG1 || || Formamidopyrimidine DNA glycosylase, involved in repair of gamma-irradiated DNA; Hap43p-repressed gene || 1 -0.64 -0.74 -0.23 -0.63 0.21 0.40 -0.33 -0.45 -0.07 -0.56 -0.05 -0.02 -0.40 -0.18 0.33 0.18
10802 || orf19.2131 || || || Ortholog(s) have ubiquitin-protein ligase activity and role in protein ubiquitination, ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway || 1 -0.84 -0.99 -0.31 -0.62 0.02 0.47 -0.47 -0.35 0.06 -0.30 -0.21 0.20 -0.64 0.46 0.68 0.40
10803 || orf19.3929 || || || Ortholog(s) have mitochondrion localization || 1 -0.50 -0.41 -0.44 -0.69 -0.22 0.18 -0.37 -0.25 -0.17 -0.29 -0.44 0.01 -0.72 0.26 0.14 0.02
10804 || orf19.6719 || || || Putative nucleosome assembly protein; homozygous transposon insertion causes decreased colony wrinkling under filamentous growth-inducing conditions, but does not block true hyphal formation in liquid media || 1 -0.25 -0.36 -0.32 -0.35 -0.05 0.03 -0.27 -0.22 -0.12 -0.26 -0.22 -0.02 -0.37 0.11 -0.05 0.09
10805 || orf19.2581 || || || Protein with a predicted epimerase/dehydratase domain; Hap43-repressed gene || 1 -0.97 -1.83 -0.88 -0.74 -0.17 1.38 -1.62 -0.78 -0.71 -1.27 -0.90 0.87 -1.05 -0.09 0.56 0.77
10806 || orf19.1582 || || || Predicted membrane transporter; member of the drug:proton antiporter (12 spanner) (DHA1) family, major facilitator superfamily (MFS); mRNA binds She3 || 1 -0.70 -1.06 -0.37 -0.03 0.06 0.95 -1.01 -0.65 -0.54 -0.54 -0.64 0.15 -0.96 -0.04 -0.15 0.09
10807 || orf19.3888.2 || || || Dubious open reading frame || 1 -0.87 -1.02 -0.38 -0.31 -0.34 0.48 -0.42 -0.27 0.22 -0.59 -0.34 0.14 -0.86 -0.31 -0.47 0.33
10808 || orf19.5837 || || || Ortholog(s) have 4-amino-4-deoxychorismate lyase activity, role in folic acid biosynthetic process and cytoplasm localization || 1 -0.72 -0.64 -0.19 -0.61 -0.54 0.32 -0.28 -0.35 0.08 -0.41 -0.28 0.03 -0.73 -0.14 -0.36 0.38
10809 || orf19.6532 || || || Ortholog(s) have FAD transmembrane transporter activity, role in FAD transport and mitochondrion localization || 1 -1.08 -0.93 -0.95 -0.89 -0.58 0.44 -0.14 -0.69 -0.17 -0.56 -0.21 0.48 -0.74 -0.00 -0.58 0.19
10810 || orf19.1010 || MNT3 || || Mannosyltransferase; transcription elevated in cyr1, chk1, nik1, and sln1 homozygous null mutants; fungal-specific (no human or murine homolog) || 1 -0.83 -0.96 -0.69 -0.65 -0.72 0.61 -0.38 -0.18 -0.12 -0.26 0.25 0.46 -1.12 0.07 -0.84 0.45
10811 || orf19.5808 || || || Ortholog(s) have protein-lysine N-methyltransferase activity, role in negative regulation of G2/M transition of mitotic cell cycle, peptidyl-lysine methylation and cytosol, nucleus localization || 1 -0.45 -0.51 -0.11 -0.28 -0.53 0.23 -0.47 -0.34 -0.24 0.21 -0.18 0.18 -0.54 -0.02 -0.25 0.19
10812 || orf19.6209 || || || Predicted membrane transporter; monocarboxylate porter (MCP) family, major facilitator superfamily (MFS); possibly essential, disruptants not obtained by UAU1 method; rat catheter and Spider biofilm induced || 1 -1.08 -1.23 -0.15 -0.28 -0.31 0.24 -0.66 -0.59 -0.25 0.21 -0.30 0.66 -1.14 0.09 0.07 0.56
10813 || orf19.4001 || || || Ortholog(s) have role in protein insertion into mitochondrial membrane from inner side and extrinsic to mitochondrial inner membrane, mitochondrial matrix localization || 1 -0.74 -0.73 -0.41 -0.55 -0.44 0.19 -0.58 -0.59 0.12 0.11 -0.32 0.33 -0.32 0.04 -0.02 0.02
10814 || orf19.6716 || ABD1 || || SAM-dependent RNA methyltransferase; methylates mRNA 5' cap; binds phosphorylated RNA Pol II C-term domain peptide; does not bind mRNA TPase and mRNA GTase (Cet1,Cgt1); functional homolog of S. cerevisiae Abd1; rat catheter biofilm induced || 1 -0.72 -0.75 -0.26 -0.30 -0.44 -0.02 -0.65 -0.86 -0.10 -0.23 -0.29 0.15 -0.45 -0.21 -0.11 0.01
10815 || orf19.2517 || || || Predicted membrane transporter, member of the drug:proton antiporter (12 spanner) (DHA1) family, major facilitator superfamily (MFS) || 1 -1.05 -1.28 -0.14 -0.38 -0.64 0.41 -0.90 -1.19 -0.18 -0.31 -0.52 0.55 -0.96 0.11 0.07 0.37
10816 || orf19.1885 || TAF4 || || Putative TFIID subunit; mutation confers hypersensitivity to toxic ergosterol analog || 1 -0.66 -0.61 -0.26 -0.41 -0.07 0.36 -0.36 -0.51 -0.14 -0.13 -0.16 0.19 -0.26 0.21 -0.26 0.18
10817 || orf19.4288 || CTA7 || || Zn(II)2Cys6 transcription factor; activates transcription in 1-hybrid assay in S. cerevisiae; has similarity to S. cerevisiae Stb4 || 1 -0.36 -0.70 -0.29 -0.32 -0.25 0.10 -0.65 -0.51 -0.10 -0.35 -0.43 0.03 -0.37 0.04 -0.48 0.40
10818 || orf19.109 || || || Probable mitochondrial tyrosyl-tRNA synthetase, based on conservation in other fungi || 1 -0.45 -0.72 -0.20 -0.59 -0.85 0.08 -0.41 -0.39 -0.01 -0.10 -0.59 -0.05 -0.96 -0.12 -0.35 0.45
10819 || orf19.4900 || MNN12 || || Predicted alpha-1,3-mannosyltransferase activity with a role in protein glycosylation || 1 -0.73 -0.84 -0.88 -0.93 -0.72 -0.47 -0.78 -1.56 -0.26 -0.67 -0.03 0.49 -1.21 -1.01 -0.54 0.20
10820 || orf19.1032 || SKO1 || || bZIP transcription factor; involved in cell wall damage response; represses the yeast-to-hypha transition; mutants are caspofungin sensitive; induced by osmotic stress via Hog1; induced by Mnl1 under weak acid stress || 1 -0.94 -1.03 -0.54 -0.75 -1.03 -0.22 -0.73 -0.81 0.41 -0.78 1.04 0.33 -1.24 -1.05 -0.97 0.07
10821 || orf19.5673 || OPT7 || || Putative oligopeptide transporter; possibly transports GSH or related compounds; Hog1-induced; expression of OPT6, -7, or -8 does not suppress defect of mutant lacking OPT1-3; Hap43-repressed; F-12/CO2 early biofilm induced || 1 -1.89 -2.26 -0.79 -0.27 -1.12 0.44 -0.69 -0.52 -1.19 -0.95 0.71 0.81 -3.14 -1.19 -0.26 0.83
10822 || orf19.5673 || OPT7 || || Putative oligopeptide transporter; possibly transports GSH or related compounds; Hog1-induced; expression of OPT6, -7, or -8 does not suppress defect of mutant lacking OPT1-3; Hap43-repressed; F-12/CO2 early biofilm induced || 1 -1.36 -1.23 -0.11 -0.20 -0.52 0.16 -0.64 -0.53 -0.14 -0.70 0.81 0.65 -1.21 -1.28 -0.06 0.72
10823 || orf19.2897 || SOU2 || || Protein similar to Sou1; not required for utilization of L-sorbose; Spider biofilm induced || 1 -1.78 -1.31 -1.06 -1.23 -0.50 0.49 -1.63 -2.13 -0.69 -1.08 0.35 1.34 -2.11 0.44 -0.38
10824 || orf19.1573 || || || Ortholog(s) have endoplasmic reticulum, fungal-type vacuole membrane localization || 1 -0.90 -0.67 -0.55 -0.65 -0.19 0.25 -0.38 -0.42 -0.15 -0.18 0.34 0.47 -0.34 -0.69 0.29 -0.14
10825 || orf19.2896 || SOU1 || || Enzyme involved in utilization of L-sorbose; has sorbitol dehydrogenase, fructose reductase, and sorbose reductase activities; NAD-binding site motif; transcriptional regulation affected by chromosome 5 copy number; Hap43p-induced gene || 1 -2.30 -2.21 -2.00 -1.83 -1.00 0.09 -1.68 -1.31 -1.42 -1.72 1.93 2.15 -2.58 -2.33 0.34 -0.70
10826 || orf19.2896 || SOU1 || || Enzyme involved in utilization of L-sorbose; has sorbitol dehydrogenase, fructose reductase, and sorbose reductase activities; NAD-binding site motif; transcriptional regulation affected by chromosome 5 copy number; Hap43p-induced gene || 1 -1.61 -1.52 -1.57 -1.71 -0.80 -0.10 -1.03 -0.88 -1.03 -1.45 1.70 1.92 -1.71 -2.13 0.30 -0.77
10827 || orf19.4246 || || || Protein with similarity to S. cerevisiae Ykr070w; Tn mutation affects filamentation; Hog1-repressed; colony morphology-related gene regulation by Ssn6p; induced during cell wall regeneration; possibly essential || 1 -0.89 -1.01 -1.32 -1.08 -0.45 -0.01 -0.38 -0.37 0.12 -0.80 1.00 1.37 -1.97 -1.24 0.59 0.41
10828 || orf19.4246 || || || Protein with similarity to S. cerevisiae Ykr070w; Tn mutation affects filamentation; Hog1-repressed; colony morphology-related gene regulation by Ssn6p; induced during cell wall regeneration; possibly essential || 1 -0.97 -1.06 -0.88 -0.50 -0.19 0.29 -0.45 -0.39 0.35 -0.98 1.48 1.42 -1.81 -1.64 0.33 0.32
10829 || orf19.4769 || IPT1 || || Inositol phosphoryl transferase; catalyzes the synthesis of the most abundant sphingolipid, mannose-(inositol-P)2-ceramide, M(IP)2C, from MIPC; required for wild-type membrane localization of Cdr1; Spider biofilm induced || 1 -0.97 -1.38 -1.61 -0.69 -0.77 -0.80 -0.11 -0.90 -1.29 -0.88 0.59 1.28 -1.56 -1.39 0.76 0.51
10830 || orf19.2244 || || || Similar to oxidoreductases and to S. cerevisiae Yjr096wp; Sfu1 repressed; induced by benomyl treatment, Ssr1; Hap43-repressed; flow model biofilm repressed || 1 -1.12 -1.19 -1.21 -0.55 -0.87 -0.32 -1.50 -1.63 -1.37 -1.02 1.20 1.90 -2.93 -2.48 0.91 0.82
10831 || orf19.2244 || || || Similar to oxidoreductases and to S. cerevisiae Yjr096wp; Sfu1 repressed; induced by benomyl treatment, Ssr1; Hap43-repressed; flow model biofilm repressed || 1 -0.27 -0.31 -0.26 0.62 -0.74 -0.41 -1.19 -1.15 -0.69 -0.76 1.32 1.49 -1.85 -2.48 0.90 0.51
10832 || orf19.2881 || MNN4 || || Regulator of mannosylphosphorylation of N-linked mannans to cell wall proteins; no role in virulence or normal interaction with macrophages; mutant induces inflammatory cytokines in dendritic cells; rat catheter and Spider biofilm induced || 1 -1.70 -1.62 -0.45 -0.56 -1.05 -0.45 -1.65 -1.95 -0.41 -1.59 0.38 1.48 -0.81 -1.40 1.88 1.12
10833 || orf19.851 || || || Protein of unknown function; repressed by Rim101; negatively modulates intracellular ATP levels during the development of azole resistance; induced by Ca(2+) in a calcineurin-dependent manner; Spider biofilm induced || 1 -2.68 -2.28 -0.73 -1.27 -0.75 0.50 -2.51 -2.57 -0.71 -0.98 0.36 1.71 -1.59 -0.99 1.84 1.13
10834 || orf19.889 || THI20 || || Putative trifunctional enzyme of thiamine biosynthesis, degradation and salvage; Spider biofilm induced || 1 -1.22 -1.32 -0.02 -0.71 -0.78 0.30 -1.19 -1.67 -0.83 -0.22 0.30 1.35 -1.06 -0.73 0.97 0.53
10835 || orf19.5026 || || || C2H2 transcription factor; Spider biofilm induced || 1 -0.90 -0.76 -0.53 -0.10 -0.44 -0.25 -0.45 -0.72 -0.04 -0.06 0.24 0.41 -0.62 0.07 0.81 -0.08
10836 || orf19.5805 || DLD1 || || Putative D-lactate dehydrogenase; white cell-specific trancript; colony morphology-related gene regulation by Ssn6; Hap43-repressed; rat catheter biofilm induced; Spider biofilm repressed || 1 -0.35 -0.62 -0.06 0.20 -0.48 -0.29 -0.07 -0.38 -0.19 -0.78 0.31 0.56 -0.42 -0.51 0.64 0.44
10837 || orf19.2772 || HOS3 || || Histone deacetylase; similar to S. cerevisiae Hos3p; greater expression and longer mRNA in white cells, compared to opaque cells; has conserved deacetylation motif || 1 -0.34 -0.47 -0.20 -0.01 -0.25 -0.25 -0.01 -0.26 -0.04 -0.60 0.38 0.81 -0.51 -0.20 0.07 0.23
10838 || orf19.4006 || || || Ortholog(s) have cytosol, nucleus localization || 1 -0.27 -0.36 -0.23 -0.20 0.03 -0.24 -0.10 0.05 0.18 -0.41 0.26 0.58 -0.23 -0.35 0.34 0.22
10839 || orf19.1559 || HOM2 || || Aspartate-semialdehyde dehydrogenase; forms a homodimer; conserved in bacteria, archaea, and fungi but not in mammals; ketoconazole-repressed; protein present in exponential and stationary growth phase yeast cultures; GlcNAc-induced protein || 1 -0.16 -0.36 0.33 -0.14 -0.26 0.06 -0.28 0.38 -0.36 -0.04 0.84 -0.12
10840 || orf19.4475 || KTR4 || || Mannosyltransferase; induced during cell wall regeneration; fungal-specific (no human or murine homolog); Bcr1-repressed in RPMI a/a biofilms || 1 -0.30 -0.35 -0.41 -0.56 -0.15 0.21 -0.55 -0.30 -0.22 0.01 -0.30 0.38 -0.28 0.22 1.11 0.31
10841 || orf19.4196 || || || Dubious open reading frame || 1 -0.47 -0.39 -0.84 0.37 0.58 -0.32 -0.44 -0.13 0.13 -0.51 1.29 -0.65 0.44 0.85 0.54
10842 || orf19.4147 || GLR1 || || Glutathione reductase; upregulated by human neutrophils; oxidative stress-induced regulation via Cap1p; overexpression correlates with multidrug resistance in a cap1 mutant, farnesol induced; stationary phase enriched protein || 1 -0.63 -0.62 -0.53 -0.62 0.14 0.69 -0.57 -0.55 -0.11 0.05 0.25 0.89 -0.61 -0.11 0.95 0.19
10843 || orf19.2113 || || || Putative integral peroxisomal membrane protein; Hap43p-repressed gene || 1 -0.71 -0.69 -0.83 -0.94 0.37 0.36 -0.52 -0.43 -0.03 0.37 -0.03 0.46 -0.50 0.25 0.98 0.41
10844 || orf19.2113 || || || Putative integral peroxisomal membrane protein; Hap43p-repressed gene || 1 -0.64 -0.64 -0.63 -0.66 0.33 0.33 -0.33 -0.32 -0.17 0.46 0.07 0.37 -0.56 0.17 1.02 0.67
10845 || orf19.6266 || || || Protein of unknown function; Spider biofilm induced || 1 -0.69 -0.80 -0.95 -1.00 -0.16 0.34 0.13 -0.47 -0.00 0.69 -0.03 0.58 -0.27 0.27 0.72 0.20
10846 || orf19.2597 || MRS2 || || Putative magnesium ion transporter, mitochondrial; fungal-specific (no human or murine homolog) || 1 -0.73 -0.50 -0.69 -0.87 0.23 0.12 0.08 -0.08 0.15 0.13 -0.11 0.53 -0.23 -0.10 0.77 0.12
10847 || orf19.3638 || PGA46 || || Putative GPI-anchored protein; secreted; fluconazole-induced || 1 -0.73 -0.28 -1.71 -1.39 0.30 0.11 -0.22 -0.60 -0.42 0.02 0.18 0.26 -0.42 1.42 0.28
10848 || orf19.6773 || ECM29 || || Putative scaffold protein; assists in association of the proteasome core particle with the regulatory particle; ortholog of S. cerevisiae Ecm29; transposon mutation affects filamentous growth; flow model biofilm repressed || 1 -0.79 -0.37 -1.11 -1.06 0.43 -0.25 -0.06 -0.54 -0.30 -0.06 0.55 0.68 -0.69 -0.19 1.46 0.89
10849 || orf19.5543 || || || Ortholog(s) have cell division site, cytosol localization || 1 -0.23 -0.20 -0.41 -0.64 0.34 0.14 -0.15 -0.31 0.09 -0.15 -0.07 0.32 -0.17 0.20 0.74 0.28
10850 || orf19.5584 || PEP3 || || Peptidase; activity useful for strain identification by multilocus enzyme electrophoresis (MLEE); clade-associated gene expression || 1 -0.22 -0.39 -0.63 -0.78 0.38 0.02 0.01 -0.29 0.09 -0.23 -0.18 0.39 -0.22 0.48 0.69 0.32
10851 || orf19.5718 || || || Has domain(s) with predicted zinc ion binding activity and role in intracellular protein transport, vesicle-mediated transport || 1 -0.34 -0.49 -0.65 -0.83 0.24 0.09 -0.07 -0.30 0.05 -0.23 -0.11 0.43 -0.41 0.39 0.58 0.56
10852 || orf19.5543 || || || Ortholog(s) have cell division site, cytosol localization || 1 -0.38 -0.46 -0.74 -0.89 0.20 -0.11 -0.26 -0.53 -0.39 -0.26 -0.42 0.20 -0.54 0.31 0.57 0.17
10853 || orf19.5584 || PEP3 || || Peptidase; activity useful for strain identification by multilocus enzyme electrophoresis (MLEE); clade-associated gene expression || 1 -0.30 -0.45 -0.57 -0.69 0.22 0.05 -0.19 -0.43 -0.06 -0.33 -0.26 0.10 -0.38 0.30 0.66 0.20
10854 || orf19.5718 || || || Has domain(s) with predicted zinc ion binding activity and role in intracellular protein transport, vesicle-mediated transport || 1 -0.40 -0.33 -0.71 -0.79 0.37 0.09 -0.18 -0.44 -0.16 -0.46 -0.21 0.05 -0.31 0.11 0.50 0.23
10855 || orf19.3187 || ZNC1 || || Zn(2)-Cys(6) transcription factor; regulated by Gcn2 and Gcn4; gene located in zinc cluster region of Chromosome 5, near the MTL locus; required for yeast cell adherence to silicone substrate; Spider biofilm induced || 1 -0.20 -0.27 -0.87 -0.83 0.52 0.39 -0.20 -0.65 -0.27 -0.34 -0.42 0.07 -0.19 0.09 0.50 0.33
10856 || orf19.5040 || || || Ortholog(s) have nucleocytoplasmic transporter activity, phospholipid binding, single-stranded DNA binding activity || 1 -0.20 -0.23 -0.63 -0.92 0.46 0.36 -0.03 -0.47 -0.70 -0.30 0.21 0.46 0.17 -0.30 0.85 -0.02
10857 || orf19.3192 || STI1 || || Protein that interacts with Cdc37 and Crk1 in two-hybrid; may be involved in Cdc37 chaperone activity; soluble protein in hyphae; protein in exponential and stationary phase yeast cultures; YNB biofilm induced; Spider biofilm induced || 1 -0.35 -0.19 -0.83 -1.32 0.54 0.89 -0.31 -0.39 -0.97 -0.61 0.11 0.13 0.04 -0.22 0.54 -0.08
10858 || orf19.2654 || RMS1 || || Putative lysine methyltransferase; Hap43-induced; protein induced during mating; possibly essential, disruptants not obtained by UAU1 method; rat catheter and Spider biofilm induced || 1 -0.38 -0.48 -1.74 -2.47 0.85 0.81 0.35 -0.90 -1.68 0.06 0.70 0.04 0.08 0.02 0.77 0.03
10859 || orf19.7654 || CPR6 || || Putative peptidyl-prolyl cis-trans isomerase; macrophage/pseudohyphal-repressed; heavy metal (cadmium) stress-induced; heterozygous null mutant displays sensitivity to virgineone; rat catheter biofilm induced || 1 -0.64 -0.55 -1.63 -1.67 1.06 1.12 0.15 -0.15 -0.40 -0.09 0.57 0.30 -0.95 0.11 0.75 0.25
10860 || orf19.7654 || CPR6 || || Putative peptidyl-prolyl cis-trans isomerase; macrophage/pseudohyphal-repressed; heavy metal (cadmium) stress-induced; heterozygous null mutant displays sensitivity to virgineone; rat catheter biofilm induced || 1 -0.66 -0.64 -1.31 -1.74 0.92 1.08 0.36 -0.01 -0.39 -0.44 0.48 0.13 -0.79 -0.42 0.65 0.20
10861 || orf19.6672 || MDJ1 || || Putative member of the HSP40 (DnaJ) family of chaperones; rat catheter and Spider biofilm induced || 1 -0.68 -0.70 -1.03 -1.43 1.30 1.28 -0.13 -0.31 -0.38 -0.15 -0.05 0.08 -0.32 -0.26 0.68 -0.12
10862 || orf19.6672 || MDJ1 || || Putative member of the HSP40 (DnaJ) family of chaperones; rat catheter and Spider biofilm induced || 1 -0.73 -0.60 -0.98 -1.73 1.62 1.39 0.03 -0.12 -0.46 -0.12 0.22 -0.06 0.02 -0.15 0.97 -0.08
10863 || orf19.3399 || || || Ortholog(s) have histone binding activity, role in histone exchange and Swr1 complex, cytoplasm localization || 1 -0.60 -0.53 -0.78 -0.99 0.63 0.64 -0.46 -0.30 -0.20 -0.31 0.24 0.35 -0.17 -0.20 0.52 -0.29
10864 || orf19.3153 || MSS4 || || Phosphatidylinositol-4-phosphate 5-kinase; activity induced by phosphatidic acid (Pld1 product); macrophage/pseudohyphal-repressed; mRNA binds to She3, localized to yeast cell buds and hyphal tips; Hap43-induced; Spider biofilm induced || 1 -0.97 -1.10 -1.18 -1.45 0.75 0.86 -0.03 -0.59 -0.93 -0.47 0.66 0.27 -0.08 -0.03 0.53 0.11
10865 || orf19.25 || || || Ortholog(s) have tRNA (guanine) methyltransferase activity, role in tRNA methylation and cytoplasm, nucleolus localization || 1 -1.56 -1.37 -1.71 -2.16 0.78 1.11 0.25 -0.66 -0.73 0.40 0.38 0.32 -0.09 -0.09 0.84 -0.11
10866 || orf19.25 || || || Ortholog(s) have tRNA (guanine) methyltransferase activity, role in tRNA methylation and cytoplasm, nucleolus localization || 1 -1.85 -1.35 -2.23 -1.92 0.95 0.95 0.01 -0.71 -0.93 0.37 0.20 0.17 -0.24 -0.53 0.83 -0.24
10867 || orf19.7349 || CHS4 || || Activator of Chs3p chitin synthase; required for wild-type wall chitin content, but not for hyphal growth; mutant resistant to Calcofluor white; prenylation and 2 transmembrane segments predicted; functional homolog of S. cerevisiae Chs4p || 1 -0.70 -0.78 -1.20 -0.86 0.26 0.25 -0.17 -0.40 -0.67 0.28 0.49 0.46 -0.02 -0.08 0.53 0.27
10868 || orf19.3840 || || || Putative serine/threonine kinase similar to S. cerevisiae Sak1; possibly an essential gene, disruptants not obtained by UAU1 method; Spider biofilm induced || 1 -0.80 -0.65 -1.03 -0.99 0.84 0.59 -0.20 -0.19 -0.28 -0.06 0.44 0.45 0.03 -0.27 1.48 0.17
10869 || orf19.3840 || || || Putative serine/threonine kinase similar to S. cerevisiae Sak1; possibly an essential gene, disruptants not obtained by UAU1 method; Spider biofilm induced || 1 -0.60 -0.55 -1.15 -1.04 0.87 0.44 -0.16 -0.15 -0.47 -0.24 0.32 0.11 0.01 -0.42 1.26 -0.09
10870 || orf19.5607 || || || Ortholog of C. dubliniensis CD36 : Cd36_63860, C. parapsilosis CDC317 : CPAR2_601140, Candida tenuis NRRL Y-1498 : CANTEDRAFT_92714 and Debaryomyces hansenii CBS767 : DEHA2A06072g || 1 -1.16 -0.99 -1.14 -1.42 0.98 0.64 0.29 -0.08 -0.42 0.32 0.50 0.45 0.70 -0.16 1.11 0.17
10871 || orf19.3341 || || || Putative tRNA-Arg synthetase; essential; genes encoding ribosomal subunits, translation factors, and tRNA synthetases are downregulated upon phagocytosis by murine macrophage; downregulated by growth in the mouse cecum || 1 -0.53 -0.53 -0.91 -1.02 0.42 0.49 -0.11 0.13 -0.72 0.38 0.58 0.37 -0.47 0.09 0.91 0.33
10872 || orf19.6723 || || || Protein of unknown function; Spider biofilm induced || 1 -0.87 -0.96 -0.54 -1.29 0.53 0.87 -0.08 -0.54 -0.28 0.57 -0.03 0.46 -0.16 -0.07 0.46 0.10
10873 || orf19.6723 || || || Protein of unknown function; Spider biofilm induced || 1 -1.10 -0.98 -0.82 -1.22 0.54 0.78 -0.04 -0.79 -0.61 0.10 -0.58 -0.19 -0.01 -0.17 0.44 -0.76
10874 || orf19.7483 || CRM1 || || Functional homolog of S. cerevisiae Crm1, which acts in protein nuclear export; predicted to be resistant to antifungal drug leptomycin B; partially suppresses signal transduction defects of S. cerevisiae ste20 mutant || 1 -0.47 -0.61 -0.89 -0.92 0.47 0.19 -0.15 -0.32 -0.42 -0.35 -0.04 -0.13 -0.33 -0.25 0.62 -0.16
10875 || orf19.3188 || TAC1 || || Zn(2)-Cys(6) transcriptional activator of drug-responsive genes (CDR1 and CDR2); binds DRE element; gene in zinc cluster region near MTL locus; resequencing indicates that TAC1 spans orf19.3188 and orf19.3189; Spider biofilm induced || 1 -0.47 -0.47 -0.82 -0.76 0.39 0.39 -0.33 -0.76 -0.28 -0.61 -0.51 -0.10 -0.20 -0.18 0.64 -0.22
10876 || orf19.3188 || TAC1 || || Zn(2)-Cys(6) transcriptional activator of drug-responsive genes (CDR1 and CDR2); binds DRE element; gene in zinc cluster region near MTL locus; resequencing indicates that TAC1 spans orf19.3188 and orf19.3189; Spider biofilm induced || 1 -0.52 -0.52 -0.87 -0.73 0.47 0.35 -0.38 -0.72 -0.33 -0.66 -0.50 -0.08 -0.33 -0.19 0.56 -0.10
10877 || orf19.881 || DFG16 || || Rim101 pathway protein that acts in Rim101 processing; regulates filamentation in response to alkaline pH; required for host tissue invasion during infection; flow model biofilm induced || 1 -0.39 -0.31 -0.65 -0.66 0.62 0.35 -0.38 -0.51 -0.18 -0.62 -0.16 -0.00 -0.10 -0.07 0.49 -0.07
10878 || orf19.418 || KOG1 || || Putative TORC1 subunit; heterozygous null mutant displays sensitivity to rapamycin; likely to be essential for growth, based on an insertional mutagenesis strategy || 1 -0.39 -0.62 -0.57 -0.55 0.50 0.14 -0.16 -0.56 -0.09 -0.49 0.05 0.07 0.07 -0.31 0.56 -0.09
10879 || orf19.254 || || || Protein of unknown function; Hog1p-repressed; Spider biofilm induced || 1 -1.04 -1.19 -0.74 -0.54 1.30 0.74 -0.76 -0.49 -0.71 -0.64 -0.26 -0.42 0.19 -0.13 1.34 -0.54
10880 || orf19.3003 || || || Putative lipid-binding protein with a predicted role in calcium-dependent phospholipid-binding || 1 -0.73 -0.62 -0.20 -0.45 0.68 0.17 -0.26 -0.21 -0.07 -0.02 -0.18 -0.04 0.12 -0.08 0.36 -0.23
10881 || orf19.3003 || || || Putative lipid-binding protein with a predicted role in calcium-dependent phospholipid-binding || 1 -0.69 -0.80 -0.35 -0.56 0.33 0.11 -0.35 -0.37 -0.02 -0.14 -0.39 -0.17 -0.01 -0.17 0.34 -0.41
10882 || orf19.3003 || || || Putative lipid-binding protein with a predicted role in calcium-dependent phospholipid-binding || 1 -0.79 -0.88 -0.43 -0.69 0.34 0.22 -0.60 -0.66 -0.09 -0.23 -0.32 -0.04 0.08 -0.05 0.47 -0.11
10883 || orf19.3003 || || || Putative lipid-binding protein with a predicted role in calcium-dependent phospholipid-binding || 1 -0.59 -0.62 -0.43 -0.57 0.42 0.25 -0.22 -0.31 -0.14 -0.21 -0.40 0.04 0.08 -0.15 0.69 -0.06
10884 || orf19.3003 || || || Putative lipid-binding protein with a predicted role in calcium-dependent phospholipid-binding || 1 -0.74 -0.77 -0.40 -0.53 0.52 0.52 -0.23 -0.24 -0.13 -0.15 -0.19 0.18 0.08 0.25 0.86 -0.10
10885 || orf19.7060 || || || Ortholog of C. dubliniensis CD36 : Cd36_70070, C. parapsilosis CDC317 : CPAR2_301080, Debaryomyces hansenii CBS767 : DEHA2F22946g and Pichia stipitis Pignal : PICST_46820 || 1 -1.70 -1.64 -1.51 -1.10 1.52 1.56 -0.46 -0.61 -0.05 -0.20 -0.24 -0.66 -0.67 0.10 1.36 -0.29
10886 || orf19.7060 || || || Ortholog of C. dubliniensis CD36 : Cd36_70070, C. parapsilosis CDC317 : CPAR2_301080, Debaryomyces hansenii CBS767 : DEHA2F22946g and Pichia stipitis Pignal : PICST_46820 || 1 -1.81 -1.79 -1.40 -1.45 1.68 1.72 -0.51 -0.81 -0.18 -0.70 -0.08 -0.28 -1.14 -0.60 1.41 0.53
10887 || orf19.3508 || || || Putative protein of unknown function; stationary phase enriched protein || 1 -1.23 -1.32 -0.96 -0.89 1.10 0.94 -0.57 -0.49 -0.26 -0.85 -0.07 0.32 -0.51 0.22 0.63 0.35
10888 || orf19.1952 || || || Protein not essential for viability; merged with orf19.1953 in Assembly 21 || 1 -1.01 -1.12 -0.67 -1.04 0.31 0.78 -0.25 -0.38 -0.28 -0.39 0.06 0.39 -0.35 0.47 0.51 -0.17
10889 || orf19.5439 || || || Ortholog of C. parapsilosis CDC317 : CPAR2_504010, C. dubliniensis CD36 : Cd36_80270, Lodderomyces elongisporus NRLL YB-4239 : LELG_02294 and Pichia stipitis Pignal : PICST_29581 || 1 -0.61 -0.66 -0.45 -0.63 0.41 0.92 -0.36 -0.20 0.21 -0.14 -0.18 0.14 -0.63 -0.05 0.22 -0.32
10890 || orf19.4817 || RAM2 || || Alpha subunit of heterodimeric protein geranylgeranyltransferase type I and farnesyltransferase; a-specific transcript; lovastatin, fluconazole regulated; GGTase I binds zinc, is Mg-dependent; Cdc42 substrate; rat catheter biofilm repressed || 1 -0.38 -0.36 -0.71 -0.94 0.97 1.00 -0.43 -0.31 -0.21 -0.31 -0.43 0.05 -0.56 -0.10 0.26 -0.08
10891 || orf19.4234 || || || Protein of unknown function; Hap43-induced gene; Ctr86 ortholog in S. cerveisiae is essential; Spider biofilm induced || 1 -0.38 -0.50 -0.72 -0.82 0.59 1.04 -0.01 -0.99 -0.37 -0.31 -0.13 -0.07 -0.28 0.06 0.47 -0.05
10892 || orf19.7254 || || || Ortholog(s) have role in mRNA metabolic process, mitochondrial translational initiation and extrinsic to membrane, mitochondrial inner membrane localization || 1 -0.44 -0.39 -0.25 -0.43 0.60 0.98 -0.09 -0.56 -0.30 -0.10 -0.20 0.31 -0.11 -0.30 0.74 0.06
10893 || orf19.7397 || || || Ortholog(s) have sequence-specific DNA binding activity and cytoplasm, nucleus, spindle localization || 1 -0.41 -0.41 -0.34 -0.63 0.36 0.62 -0.07 -0.38 0.04 0.06 -0.19 0.49 -0.12 -0.30 0.52 0.07
10894 || orf19.3202 || || || Ortholog of C. dubliniensis CD36 : Cd36_51590, C. parapsilosis CDC317 : CPAR2_303610, Candida tenuis NRRL Y-1498 : CANTEDRAFT_135127 and Debaryomyces hansenii CBS767 : DEHA2E19074g || 1 -0.68 -0.78 -1.15 -1.48 0.72 0.40 0.06 -0.66 0.08 -0.34 -0.17 0.77 0.46 -0.06 0.59 0.00
10895 || orf19.3402 || FPG1 || || Formamidopyrimidine DNA glycosylase, involved in repair of gamma-irradiated DNA; Hap43p-repressed gene || 1 -0.52 -0.61 -0.42 -0.56 0.35 0.67 -0.07 -0.09 0.37 -0.26 0.14 0.09 -0.22 -0.28 0.45 0.26
10896 || orf19.974 || ROT2 || || Alpha-glucosidase II, catalytic subunit, required for N-linked protein glycosylation and normal cell wall synthesis; alkaline downregulated || 1 -0.81 -0.77 -0.79 -0.58 0.77 0.36 -0.09 -0.19 0.27 0.00 0.10 0.27 -0.44 -0.08 0.37 0.40
10897 || orf19.974 || ROT2 || || Alpha-glucosidase II, catalytic subunit, required for N-linked protein glycosylation and normal cell wall synthesis; alkaline downregulated || 1 -0.43 -0.59 -0.61 -0.31 0.53 0.15 0.04 -0.01 -0.11 -0.23 0.14 0.16 -0.40 -0.41 0.38 0.36
10898 || orf19.4913 || || || Ortholog(s) have ubiquitin binding activity, role in cellular protein localization, positive regulation of deubiquitinase activity and cell cortex of cell tip, cell division site, cytosol localization || 1 -0.44 -0.74 -0.77 -1.12 1.41 0.37 -0.64 -0.51 -0.58 -0.91 0.70 0.38 0.14 0.09 1.21 0.36
10899 || orf19.3728 || || || Ortholog(s) have protein phosphatase 1 binding, protein phosphatase type 1 regulator activity, role in chromosome segregation, regulation of phosphoprotein phosphatase activity and cytoplasm localization || 1 -0.34 -0.38 -0.85 -0.69 0.56 -0.10 -0.14 -0.13 -0.51 -0.16 0.43 0.27 0.21 0.63 0.83 0.17
10900 || orf19.73 || || || Putative metalloprotease; associates with ribosomes and is involved in ribosome biogenesis; Spider biofilm induced || 1 -0.89 -0.99 -1.14 -1.46 0.32 -0.04 -0.38 -0.81 -0.68 0.69 -0.14 -0.14 0.33 0.15 0.46 -0.03
10901 || orf19.6727 || RIT1 || || Putative initiator tRNA methionine ribosyltransferase; fungal-specific (no human or murine homolog) || 1 -0.60 -0.23 -0.96 -0.55 0.21 0.37 -0.20 -0.17 -0.54 -0.02 -0.08 -0.04 0.21 0.10 0.29 -0.23
10902 || orf19.6727 || RIT1 || || Putative initiator tRNA methionine ribosyltransferase; fungal-specific (no human or murine homolog) || 1 -0.75 -0.13 -0.77 -0.97 0.30 0.08 -0.30 -0.32 -0.34 -0.26 0.06 -0.53 0.24 -0.06 0.41 -0.32
10903 || orf19.6391 || || || Protein of unknown function; transcript upregulated in azole-resistant strain overexpressing MDR1; Spider biofilm induced || 1 -0.63 -0.62 -0.10 -0.53 -0.35 0.13 -0.49 0.02 -0.44 -0.15 -0.56 0.35 -0.43 -0.43 0.01 -0.13
10904 || orf19.2897 || SOU2 || || Protein similar to Sou1; not required for utilization of L-sorbose; Spider biofilm induced || 1 -1.66 -1.82 -0.57 -1.25 -0.73 1.32 -1.79 -1.09 -0.58 -0.85 0.10 0.90 -1.62 -0.54 0.56 -1.59
10905 || orf19.2897 || SOU2 || || Protein similar to Sou1; not required for utilization of L-sorbose; Spider biofilm induced || 1 -0.68 -0.89 -0.72 -1.13 -0.39 1.35 -1.18 -0.74 -0.86 -0.85 -0.44 1.31 -0.84 -0.62 0.58 -0.96
10906 || orf19.6532 || || || Ortholog(s) have FAD transmembrane transporter activity, role in FAD transport and mitochondrion localization || 1 -0.19 -0.39 0.20 -0.15 -0.01 0.43 -0.22 -0.24 -0.35 -0.25 -0.17 0.38 -0.46 -0.08 -0.03 -0.19
10907 || orf19.6596 || || || Putative esterase; possibly transcriptionally regulated by Tac1; induced by Mnl1 under weak acid stress; protein present in exponential and stationary growth phase yeast cultures; Spider biofilm repressed || 1 -0.65 -0.72 -0.34 -0.37 -0.38 0.23 -0.34 -0.20 -0.88 -1.08 -0.02 0.13 -0.87 0.07 0.02 -0.26
10908 || orf19.6596 || || || Putative esterase; possibly transcriptionally regulated by Tac1; induced by Mnl1 under weak acid stress; protein present in exponential and stationary growth phase yeast cultures; Spider biofilm repressed || 1 -0.75 -0.54 -0.12 -0.05 -0.32 0.54 -0.44 -0.22 -0.43 -0.72 -0.03 0.21 -0.29 0.29 0.11 0.15
10909 || orf19.7497 || || || Ortholog(s) have ubiquitin-protein ligase activity, role in protein ubiquitination involved in ubiquitin-dependent protein catabolic process and Cul3-RING ubiquitin ligase complex, cytoplasm, nucleus localization || 1 -0.41 -0.16 -0.03 -0.18 0.13 -0.17 0.03 -0.35 0.08 -0.28 -0.20 -0.01 -0.11 -0.29 0.10 0.20
10910 || orf19.974 || ROT2 || || Alpha-glucosidase II, catalytic subunit, required for N-linked protein glycosylation and normal cell wall synthesis; alkaline downregulated || 1 -0.71 -0.45 -0.03 -0.24 0.09 -0.07 -0.13 -0.25 -0.29 -0.51 -0.27 0.10 -0.54 -0.41 0.21 0.28
10911 || orf19.2791 || BBC1 || || Putative SH3-domain-containing protein || 1 -0.24 -0.24 -0.08 -0.08 0.05 -0.26 -0.14 -0.26 0.05 -0.52 -0.25 0.11 -0.49 -0.72 0.33 0.29
10912 || orf19.881 || DFG16 || || Rim101 pathway protein that acts in Rim101 processing; regulates filamentation in response to alkaline pH; required for host tissue invasion during infection; flow model biofilm induced || 1 -0.02 -0.08 0.10 -0.19 0.17 -0.14 -0.41 -0.36 -0.20 -1.02 -0.30 -0.25 -0.34 -0.40 0.08 -0.02
10913 || orf19.2574 || || || Ortholog(s) have Golgi apparatus localization || 1 -0.19 -0.19 0.10 -0.33 -0.08 0.28 -0.69 -0.63 -0.02 -0.68 0.05 0.07 -0.18 -0.47 0.02 -0.03
10914 || orf19.778 || PIL1 || || Eisosome component; predicted role in endocytosis; echinocandin-binding protein; localizes to cell surface of hyphae, but not yeast-form cells; Hap43, YNB biofilm induced; rat catheter biofilm repressed || 1 -0.42 -0.36 -0.42 -0.12 -0.89 0.15 -0.81 -1.10 -0.72 -1.25 -0.22 0.07 0.04 -0.77 0.88 -0.06
10915 || orf19.6763 || SLK19 || || Alkaline-induced protein of plasma membrane; affects cell aggregation, cell wall; similar to S. cerevisiae Slk19p (a kinetochore protein with roles in mitosis, meiosis); required for wild-type virulence in mouse; macrophage-downregulated || 1 -0.46 -0.43 -0.15 -0.07 -0.33 0.38 -0.48 -0.66 -0.58 -1.04 -0.35 0.12 -0.02 -0.60 0.45 -0.25
10916 || orf19.5672 || MEP2 || || Ammonium permease and regulator of nitrogen starvation-induced filamentation; 11 predicted transmembrane regions; in low nitrogen cytoplasmic C-terminus activates Ras/cAMP and MAPK signal transduction pathways to induce filamentation || 1 -1.20 -1.31 0.50 0.76 -0.88 0.26 -1.70 -1.71 -1.96 -1.88 -1.12 -0.04 -0.95 -2.76 1.04 0.89
10917 || orf19.6160 || || || Ortholog(s) have role in eisosome assembly and eisosome, membrane raft, mitochondrion, plasma membrane localization || 1 -0.15 -0.27 0.38 0.02 -0.31 0.46 -0.58 -0.38 -0.43 -0.50 -0.13 -0.13 -0.08 -0.54 0.17 -0.22
10918 || orf19.851 || || || Protein of unknown function; repressed by Rim101; negatively modulates intracellular ATP levels during the development of azole resistance; induced by Ca(2+) in a calcineurin-dependent manner; Spider biofilm induced || 1 -0.54 -0.57 0.47 0.24 -0.66 0.05 -0.83 -0.88 -0.36 -0.82 -0.73 0.41 -0.51 -0.36 0.08 0.10
10919 || orf19.2996 || || || Ortholog(s) have cytoplasm localization || 1 -0.43 -0.46 -0.13 -0.12 -0.48 0.29 -0.45 -0.59 -0.19 -0.82 -0.37 0.31 -0.55 -0.50 0.10 0.12
10920 || orf19.1364 || || || Ortholog of S. pombe Stm1 G-protein coupled receptor; PQ-loop domains; constitutive expression independent of MTL or white-opaque status; Hap43-repressed || 1 -0.56 -0.66 -0.11 -0.25 -1.19 -0.33 -0.27 -0.92 -0.31 -0.87 -0.62 0.59 -0.44 -0.53 -0.21 0.30
10921 || orf19.2730 || || || Has domain(s) with predicted zinc ion binding activity || 1 -0.29 -0.27 0.23 0.27 -0.03 -0.33 -0.44 -0.23 -0.18 -0.84 -0.18 0.22 -0.36 -0.61 0.07 0.08
10922 || orf19.7479 || NTH1 || || Neutral trehalase; hyphal induction in mutant delayed but not reduced overall; not required for virulence in mice; possible regulatory cAMP-dependent phosphorylation at S10,S213; Hap43-repressed gene; Spider biofilm induced || 1 -0.39 -0.44 0.42 0.65 0.09 0.40 -0.14 -0.46 -0.08 -1.29 0.14 0.32 -0.64 -0.92 -0.55 0.23
10923 || orf19.7479 || NTH1 || || Neutral trehalase; hyphal induction in mutant delayed but not reduced overall; not required for virulence in mice; possible regulatory cAMP-dependent phosphorylation at S10,S213; Hap43-repressed gene; Spider biofilm induced || 1 -0.64 -0.65 0.02 -0.07 -0.05 0.21 -0.20 -0.71 -0.22 -1.27 0.00 -0.02 -0.57 -1.15 -0.45 0.34
10924 || orf19.99 || HAL21 || || Putative phosphoadenosine-5'-phosphate or 3'-phosphoadenosine 5'-phosphosulfate phosphatase; possible role in sulfur recycling; ortholog of S. cerevisiae Met22; predicted Kex2 substrate; F-12/CO2 biofilm induced || 1 -0.20 -0.24 0.26 -0.02 0.11 0.35 -0.31 -0.41 -0.09 -0.60 -0.03 0.19 -0.07 -0.81 -0.09 0.16
10925 || orf19.5720 || || || Predicted membrane transporter, member of the monocarboxylate porter (MCP) family, major facilitator superfamily (MFS); ketoconazole or caspofungin repressed; Spider biofilm induced || 1 -0.06 -0.05 0.25 0.21 -0.08 0.36 -0.29 -0.69 0.42 -1.15 -0.42 0.17 -0.22 -1.07 -0.21 0.25
10926 || orf19.5674 || PGA10 || || GPI anchored membrane protein; utilization of hemin and hemoglobin for Fe in host; Rim101 at ph8/hypoxia/ketoconazole/ciclopirox/hypha-induced; required for RPMI biofilm formation, Bcr1-induced in a/a biofilm; rat catheter biofilm repressed || 1 0.06 -0.14 -0.06 -0.02 -0.26 -0.08 -0.47 -0.77 -0.48 -2.00 0.01 0.02 0.11 -1.05 -0.15 0.77
10927 || orf19.4170 || CSP2 || || Putative cell wall associated protein; C. albicans and C. dubliniensis specific gene highly induced during chlamydospore development in both species; localized to chlamydospore cell wall; Hap43-repressed; Spider biofilm induced || 1 0.06 -0.22 0.09 -0.01 -0.31 0.16 -0.22 -0.44 -0.47 -1.01 -0.29 -0.39 -0.26 -0.84 -0.37 0.74
10928 || orf19.4391 || || || Ortholog of C. dubliniensis CD36 : Cd36_28730, Candida tropicalis MYA-3404 : CTRG_00749 and Candida albicans WO-1 : CAWG_01683 || 1 0.16 -0.26 -0.16 -0.29 -0.47 -0.16 -0.98 -0.98 -0.88 -0.85 -0.56 0.08 -0.85 -1.50 -0.90 0.97
10929 || orf19.4391 || || || Ortholog of C. dubliniensis CD36 : Cd36_28730, Candida tropicalis MYA-3404 : CTRG_00749 and Candida albicans WO-1 : CAWG_01683 || 1 0.12 0.14 0.12 0.35 -0.19 0.24 -1.65 -2.26 -0.64 -1.48 -1.30 0.71 -1.15 -1.70 -1.40 0.68
10930 || orf19.3708 || SAP2 || || Major secreted aspartyl proteinase; utilization of protein as nitrogen source; role in virulence complicated by URA3 effects; immunoprotective; regulated by growth, albumin, drugs, white cell-type; flow model biofilm induced || 1 0.72 0.59 -0.10 0.18 -1.79 1.26 -3.15 -2.06 -2.17 -2.32 -2.34 1.06 -2.30 -4.20 0.54 -2.94
10931 || orf19.6948 || CCC1 || || Manganese transporter; required for normal filamentous growth; mRNA binds She3, localized to hyphal tips; repressed by NO, alkaline pH; colony morphology-related regulation by Ssn6; regulated by Sef1, Sfu1, Hap43; Spider biofilm induced || 1 -0.40 -0.46 -0.03 0.19 -0.33 0.01 -0.87 -0.91 -0.85 -0.16 -0.11 1.11 -0.71 -1.49 0.31 -0.70
10932 || orf19.2897 || SOU2 || || Protein similar to Sou1; not required for utilization of L-sorbose; Spider biofilm induced || 1 -1.05 -0.79 0.24 0.23 -0.97 0.35 -1.25 -1.19 -0.48 -0.40 -0.62 0.49 -1.58 0.58 -1.15
10933 || orf19.5978 || || || Has domain(s) with predicted oxidoreductase activity, transferase activity, transferring acyl groups other than amino-acyl groups, zinc ion binding activity and role in oxidation-reduction process || 1 -0.81 -0.53 0.47 0.63 -0.95 -0.89 -0.75 -0.46 -0.35 -0.45 -0.78 0.85 -0.60
10934 || orf19.3049 || || || Ortholog(s) have protein kinase activity, role in activation of bipolar cell growth, ascospore wall assembly, protein phosphorylation and cell division site, cytosol, nucleus, prospore membrane localization || 1 -0.35 -0.28 0.26 0.17 -0.06 0.17 -0.49 -0.26 -0.47 0.06 -0.28 0.06 -0.50 -0.60 -0.26 0.06
10935 || orf19.3905 || MRV5 || || Planktonic growth-induced gene || 1 -0.13 -0.11 0.16 -0.29 -0.32 0.42 -1.07 -0.87 -0.81 -0.19 -0.83 0.49 -1.60 -3.20 -0.95
10936 || orf19.3935 || || || Ortholog of Candida albicans WO-1 : CAWG_04819 || 1 -0.72 -0.54 0.55 0.03 0.12 0.09 -1.10 -0.57 -0.31 -0.06 0.09 0.27 -1.04 -2.16 -0.06 -0.45
10937 || orf19.238 || CCP1 || || Cytochrome-c peroxidase N terminus; Rim101, alkaline pH repressed; induced in low iron or by macrophage interaction; oxygen-induced activity; regulated by Sef1, Sfu1, and Hap43; Spider biofilm induced; rat catheter biofilm repressed || 1 0.04 0.20 0.32 -0.06 0.53 1.32 -0.81 -1.19 -0.75 -1.49 -0.34 0.34 -2.82 -3.57 0.35 -1.51
10938 || orf19.7098 || || || Putative protein of unknown function; Hap43-repressed; repressed by nitric oxide; Spider biofilm induced || 1 0.07 0.25 0.06 -0.02 0.46 1.08 -0.64 -1.18 -0.57 -1.77 0.42 0.71 -2.05 -2.26 -0.17 -0.05
10939 || orf19.5798 || LIG4 || || DNA ligase; mRNA detected in yeast-form and pseudohyphal cells, induced upon hyphal induction; suppresses S. cerevisiae ime1-1 mutant IME2 transcription defect; required for wild-type filamentous growth and wild-type pathogenesis || 1 -0.46 -0.41 -0.42 -0.52 0.75 0.66 -1.03 -1.00 -0.05 -0.77 0.19 0.37 -1.32 -1.90 -0.16 0.27
10940 || orf19.2021 || HGT8 || || High-affinity glucose transporter of the major facilitator superfamily; 20 members in the C. albicans glucose transporter family; 12 probable membrane-spanning segments; gene has intron; expressed in rich medium; flow model biofilm induced || 1 -1.31 -1.25 -1.09 -1.66 1.74 -1.09 -1.24 0.11 -1.72 -0.29 0.41 -2.25 -3.79 -0.01 -0.90
10941 || orf19.4673 || BMT9 || || Beta-mannosyltransferase, 9-gene family that includes characterized genes BMT1, BMT2, BMT3, and BMT4 with roles in beta-1,2-mannosylation of cell wall phosphopeptidomannan; regulated by Sef1, Sfu1, Hap43; rat catheter biofilm repressed || 1 -0.79 -0.99 0.07 -0.86 1.30 1.03 -0.52 -1.38 -0.39 -0.63 0.16 0.20 -0.99 -2.14 0.77 0.03
10942 || orf19.3112 || ZRT1 || || Putative zinc transporter; acts with Pra1 in sequestration of zinc from host tissues during infection; hyphal, macrophage-induced; alkaline induced upon adherence to polystyrene; induced in oralpharyngeal candidasis; Spider biofilm induced || 1 -0.48 -0.19 -0.63 -0.55 0.19 -0.89 -0.52 -0.51 -0.86 0.14 -0.06 0.65 -0.47 -2.17 -0.00 -0.01
10943 || orf19.2991 || HOL1 || || Putative MFS transporter; regulated by Nrg1; macrophage/pseudohyphal-repressed; induced by alpha pheromone in SpiderM medium; possibly an essential gene, disruptants not obtained by UAU1 method || 1 -0.34 -0.23 -0.99 0.38 -0.58 -0.92 -0.99 0.10 0.51 0.10 -1.53 -3.67 0.38 -0.70
10944 || orf19.3034 || RLI1 || || Member of RNase L inhibitor (RLI) subfamily of ABC family; predicted not to be a transporter; regulated by Sef1p, Sfu1p, and Hap43p || 1 -0.45 -0.44 -0.76 -0.29 -0.47 0.11 -0.29 -0.25 -1.16 0.53 0.12 0.69 -1.08 -1.50 -0.03 -0.29
10945 || orf19.4903 || || || Ortholog(s) have endoplasmic reticulum localization || 1 0.34 0.36 0.13 0.27 -0.20 -0.07 -0.27 -0.22 -0.40 -0.44 0.33 0.50 -0.48 -0.26 -0.30 0.17
10946 || orf19.5731 || PAD1 || || Putative phenylacrylic acid decarboxylase; repressed by Rgt1p || 1 0.82 0.76 0.08 -0.13 -0.26 0.38 -1.19 -1.14 -0.81 -1.31 0.21 0.62 -1.37 -1.03 -0.23 0.72
10947 || orf19.5731 || PAD1 || || Putative phenylacrylic acid decarboxylase; repressed by Rgt1p || 1 1.05 0.89 0.09 0.03 0.21 0.72 -0.58 -0.45 -0.50 -1.17 0.65 1.04 -0.42 -0.46 0.10 0.31
10948 || orf19.5862 || AFP99 || || Protein related to arginases; downregulated upon adherence to polystyrene; regulated by Gcn2p and Gcn4p || 1 0.66 0.67 0.10 0.64 0.26 0.30 -0.83 -0.82 -0.48 -0.23 0.52 1.01 -0.69 -0.73 0.23 0.04
10949 || orf19.4674.1 || CRD2 || || Metallothionein; for adaptation to growth in high copper; basal transcription is cadmium-repressed; Ssn6 regulated; complements copper sensitivity of an S. cerevisiae cup1 mutant; regulated by Sef1, Sfu1, and Hap43; Spider biofilm induced || 1 0.43 0.35 -0.26 -0.37 -0.37 -0.41 -0.93 -1.87 -2.02 -0.88 0.16 2.08 -2.16 -2.77 -0.11 -1.13
10950 || orf19.4674.1 || CRD2 || || Metallothionein; for adaptation to growth in high copper; basal transcription is cadmium-repressed; Ssn6 regulated; complements copper sensitivity of an S. cerevisiae cup1 mutant; regulated by Sef1, Sfu1, and Hap43; Spider biofilm induced || 1 0.48 0.41 -0.05 -0.25 -0.05 -0.30 -0.92 -1.53 -1.71 -1.11 0.56 1.67 -1.10 -2.65 0.36 -1.01
10951 || orf19.1926 || SEF2 || || Zn(II)2Cys6 transcription factor, required for normal resistance to copper; repressed by Sfu1 in high-iron conditions; regulated by Sef1, Sfu1, and Hap43; rat catheter and Spider biofilm induced || 1 0.44 0.26 -0.26 -0.37 0.29 -0.24 -0.65 -1.15 -1.45 -1.37 0.23 1.42 -0.66 -1.83 0.35 -0.23
10952 || orf19.1926 || SEF2 || || Zn(II)2Cys6 transcription factor, required for normal resistance to copper; repressed by Sfu1 in high-iron conditions; regulated by Sef1, Sfu1, and Hap43; rat catheter and Spider biofilm induced || 1 0.56 0.52 -0.26 -0.61 0.32 -0.09 -0.33 -0.92 -0.98 -0.83 0.68 1.43 -0.71 -1.68 0.75 0.00
10953 || orf19.1926 || SEF2 || || Zn(II)2Cys6 transcription factor, required for normal resistance to copper; repressed by Sfu1 in high-iron conditions; regulated by Sef1, Sfu1, and Hap43; rat catheter and Spider biofilm induced || 1 0.47 0.42 -0.07 -0.48 0.35 0.14 -0.35 -1.02 -1.11 -0.78 0.60 1.50 -0.57 -1.25 0.64 0.10
10954 || orf19.1926 || SEF2 || || Zn(II)2Cys6 transcription factor, required for normal resistance to copper; repressed by Sfu1 in high-iron conditions; regulated by Sef1, Sfu1, and Hap43; rat catheter and Spider biofilm induced || 1 0.37 0.41 -0.14 -0.37 0.39 0.17 -0.60 -1.24 -1.20 -1.02 0.56 1.75 -0.73 -1.51 0.63 0.26
10955 || orf19.1926 || SEF2 || || Zn(II)2Cys6 transcription factor, required for normal resistance to copper; repressed by Sfu1 in high-iron conditions; regulated by Sef1, Sfu1, and Hap43; rat catheter and Spider biofilm induced || 1 0.57 0.15 0.13 -0.34 0.46 0.09 -0.13 -0.84 -1.04 -0.94 0.39 1.55 -0.60 -1.53 0.51 0.33
10956 || orf19.6413 || || || Protein of unknown function; rat catheter biofilm induced || 1 0.22 0.22 0.31 0.14 0.27 -0.02 -0.25 -0.37 -0.92 -0.49 0.10 0.52 0.10 -0.46 -0.09 0.43
10957 || orf19.6413 || || || Protein of unknown function; rat catheter biofilm induced || 1 0.32 0.41 0.18 0.13 0.53 0.56 -0.37 -0.51 -0.66 -0.32 0.51 0.41 0.10 -0.71 -0.12 0.70
10958 || orf19.3529 || ABP2 || || Putative alpha-actinin-like protein; induced by alpha pheromone in SpiderM medium || 1 0.43 -0.02 -0.20 0.43 0.12 0.71 -0.97 -0.44 -1.78 -0.91 0.82 1.17 -0.50 -0.99 -0.05 1.23
10959 || orf19.1852 || || || Ortholog(s) have mitochondrion localization || 1 -0.22 0.23 0.14 0.78 0.02 0.71 -0.17 -0.36 -0.84 -0.99 0.64 0.79 -0.44 -0.66 0.65 0.89
10960 || orf19.1442 || PLB4.5 || || Phospholipase B; Hog1-induced; regulated by Ssn6; putative GPI-anchor; repressed during cell wall regeneration; clade-associated gene expression; Hap43-induced; rat catheter and Spider biofilm repressed || 1 0.07 0.16 0.46 0.34 0.00 0.67 -0.50 -0.50 -1.25 -1.64 0.84 1.17 -0.46 -1.67 0.51 0.53
10961 || orf19.1442 || PLB4.5 || || Phospholipase B; Hog1-induced; regulated by Ssn6; putative GPI-anchor; repressed during cell wall regeneration; clade-associated gene expression; Hap43-induced; rat catheter and Spider biofilm repressed || 1 0.00 0.14 0.38 0.43 0.68 0.68 -0.59 -0.40 -0.96 -1.58 1.02 1.08 -0.12 -1.44 0.22 0.37
10962 || orf19.4763 || || || Protein of unknown function; possibly membrane bound; mutants are viable; rat catheter biofilm repressed || 1 0.15 0.09 0.29 0.51 0.45 0.58 -0.18 -0.16 -0.47 -0.89 0.29 0.37 0.43 -1.06 0.24 0.51
10963 || orf19.277 || THI6 || || Putative thiamin-phosphate pyrophosphorylase, hydroxyethylthiazole kinase; fungal-specific; Spider biofilm induced || 1 -0.20 -0.13 0.13 -0.46 0.19 0.56 -0.36 -0.85 -0.05 -1.39 0.59 0.69 -0.26 -0.52 0.19 0.91
10964 || orf19.7522 || || || Protein with a pyridoxal phosphate-dependent transferase domain; Hap43-repressed; mutation confers hypersensitivity to amphotericin B; Spider biofilm repressed || 1 -0.30 -0.08 0.03 -0.18 0.46 0.38 -0.50 -0.42 -0.02 -0.97 0.43 0.76 0.05 -1.18 0.13 0.40
10965 || orf19.7522 || || || Protein with a pyridoxal phosphate-dependent transferase domain; Hap43-repressed; mutation confers hypersensitivity to amphotericin B; Spider biofilm repressed || 1 -0.26 0.07 0.13 0.14 0.16 0.67 -0.22 -0.40 0.11 -0.82 0.38 0.58 0.08 -0.87 -0.05 0.85
10966 || orf19.6527 || || || Pheromone-regulated protein (Prm10) of S. cerevisiae; colony morphology-related gene regulation by Ssn6; induced by Mnl1 under weak acid stress; possibly essential gene, disruptants not obtained by UAU1 method; Spider biofilm induced || 1 -0.30 -0.38 0.01 -0.03 -0.15 0.59 -0.39 -0.48 0.32 -0.69 0.49 0.87 -0.42 -0.86 -0.05 0.63
10967 || orf19.5514 || || || Ortholog of S. pombe SPCC550.08, an N-acetyltransferase; transcript induced during growth in the mouse cecum || 1 -0.46 -0.22 -0.16 -0.06 -0.36 0.27 -0.51 -0.68 -0.19 -1.16 0.89 1.71 0.04 -1.60 -0.05 0.41
10968 || orf19.5514 || || || Ortholog of S. pombe SPCC550.08, an N-acetyltransferase; transcript induced during growth in the mouse cecum || 1 -0.30 -0.54 -0.38 -0.47 -0.27 0.50 -1.09 -1.86 -0.22 -1.28 1.16 2.24 -0.82 -1.87 1.14 1.06
10969 || orf19.1442 || PLB4.5 || || Phospholipase B; Hog1-induced; regulated by Ssn6; putative GPI-anchor; repressed during cell wall regeneration; clade-associated gene expression; Hap43-induced; rat catheter and Spider biofilm repressed || 1 -0.54 -0.29 0.22 0.31 -0.34 0.82 -1.37 -1.53 -2.10 -2.21 1.08 1.20 -2.01 -1.83 0.23 0.83
10970 || orf19.1442 || PLB4.5 || || Phospholipase B; Hog1-induced; regulated by Ssn6; putative GPI-anchor; repressed during cell wall regeneration; clade-associated gene expression; Hap43-induced; rat catheter and Spider biofilm repressed || 1 -0.58 -0.53 0.15 -0.30 -0.43 0.78 -1.24 -1.35 -1.71 -2.34 1.00 1.25 -1.64 -2.18 0.35 1.14
10971 || orf19.1442 || PLB4.5 || || Phospholipase B; Hog1-induced; regulated by Ssn6; putative GPI-anchor; repressed during cell wall regeneration; clade-associated gene expression; Hap43-induced; rat catheter and Spider biofilm repressed || 1 -0.58 -0.59 -0.34 -0.26 -0.70 0.62 -1.45 -1.84 -2.22 -2.61 0.88 1.00 -1.60 -2.55 0.14 0.53
10972 || orf19.278 || || || Protein of unknown function; required for adhesion to abiotic substrate; Spider biofilm induced || 1 -0.70 -0.63 -0.45 -0.09 -0.36 0.64 -0.38 -0.59 -0.83 -0.78 0.02 0.57 -0.96 -1.02 0.01 0.45
10973 || orf19.4952 || || || Protein of unknown function; flow model biofilm induced; Spider biofilm induced || 1 0.14 0.02 -0.17 0.13 0.37 0.79 -0.57 -1.10 -0.84 -0.36 0.19 0.29 0.01 -0.42 0.82 -0.04
10974 || orf19.3854 || || || Ortholog of S. cerevisiae Sat4; amphotericin B induced; clade-associated gene expression; Spider biofilm induced || 1 -0.03 -0.12 -0.11 0.12 0.88 1.10 -0.73 -1.45 -0.72 -0.11 0.26 0.45 -0.57 -0.38 0.73 0.14
10975 || orf19.3158 || || || Ortholog(s) have cytoplasm localization || 1 -0.15 -0.06 0.21 0.15 -0.02 0.56 -0.72 -0.85 -0.68 -0.21 0.08 0.31 -0.79 -0.26 0.16 0.60
10976 || orf19.2394 || || || Ortholog(s) have cytoplasm, nucleus localization || 1 -0.07 -0.25 0.23 0.24 -0.03 0.32 -0.50 -0.56 -0.16 0.02 0.09 0.15 -0.51 -0.27 0.14 0.31
10977 || orf19.6595 || RTA4 || || Protein similar to S. cerevisiae Rsb1p, involved in fatty acid transport; transposon mutation affects filamentous growth; alkaline downregulated; caspofungin induced; possibly an essential gene; Hap43p-repressed || 1 -0.37 -0.39 0.21 -0.14 0.03 0.63 -1.01 -1.03 -0.50 -0.13 -0.15 0.26 -1.20 -0.99 0.65 0.86
10978 || orf19.5667 || MNR2 || || Putative ion transporter; fungal-specific (no human or murine homolog) || 1 -0.29 -0.29 0.16 0.10 0.16 0.69 -0.59 -0.45 -0.33 -0.25 0.08 0.72 -0.41 -0.54 0.62 0.19
10979 || orf19.5667 || MNR2 || || Putative ion transporter; fungal-specific (no human or murine homolog) || 1 -0.16 -0.17 -0.02 -0.06 0.33 0.70 -0.74 -0.58 -0.15 -0.32 0.01 0.79 -0.51 -0.34 0.79 0.42
10980 || orf19.2726 || || || Putative plasma membrane protein; Plc1-regulated; Spider biofilm induced || 1 -0.14 -0.28 0.36 0.10 0.31 0.87 -0.77 -1.17 -0.54 -1.22 0.28 0.90 -0.34 -0.55 1.08 1.13
10981 || orf19.5395 || || || Ortholog(s) have role in early endosome to late endosome transport, regulation of protein complex assembly, vacuolar acidification and RAVE complex, extrinsic to membrane localization || 1 0.31 -0.10 0.06 0.02 0.37 0.45 -0.51 -0.47 -0.08 -0.52 0.02 0.52 -0.16 -0.47 0.28 0.66
10982 || orf19.199 || || || Protein of unknown function; hyphal-induced expression; upregulated in a cyr1 null mutant || 1 -0.01 -0.11 0.24 0.70 0.20 0.54 -0.66 -0.62 0.10 -0.10 -0.01 0.60 -0.24 -0.75 0.44 0.19
10983 || orf19.7242 || NCR1 || || Putative vacuolar membrane protein; predicted role in sphingolipid metabolism; transcript regulated by Nrg1 and Mig1; induced by prostaglandins || 1 -0.34 -0.95 0.05 0.03 0.33 -0.05 -0.30 -0.16 0.26 -0.45 -0.32 0.23 0.06 -0.33 0.63 0.02
10984 || orf19.6792 || RRD1 || || Putative peptidyl-prolyl cis/trans-isomerase; caspofungin induced || 1 -0.48 -0.40 -0.28 -0.09 0.70 0.12 -0.14 -0.16 -0.02 -0.35 -0.27 0.23 0.12 -0.24 0.51 -0.17
10985 || orf19.3241 || || || Ortholog(s) have Seh1-associated complex, extrinsic to fungal-type vacuolar membrane localization || 1 -0.23 -0.28 -0.76 0.06 0.14 0.16 0.06 -0.12 -0.01 -0.22 -0.35 -0.08 -0.33 -0.25 0.20 -0.31
10986 || orf19.7267 || SAM35 || || Predicted component of the sorting and assembly machinery (SAM complex) of the mitochondrial outer membrane, involved in protein import into mitochondria || 1 -0.12 -0.18 -0.34 0.03 0.12 0.12 0.10 -0.06 -0.07 0.07 -0.20 -0.46 -0.12 -0.07 0.38 -0.26
10987 || orf19.6944 || PHB1 || || Putative prohibitin; identified in detergent-resistant membrane fraction (possible lipid raft component); predicted N-terminal acetylation; Hap43p-repressed gene || 1 -0.53 -0.16 -0.66 -0.31 0.74 0.41 -0.13 0.09 0.03 -0.03 -0.28 -0.38 -0.42 -0.42 0.47 -0.46
10988 || orf19.357 || || || Ortholog(s) have role in inner mitochondrial membrane organization, mitochondrion inheritance, mitochondrion morphogenesis, negative regulation of proteolysis, protein folding, replicative cell aging || 1 -0.25 -0.21 -0.46 -0.35 0.66 0.43 -0.05 0.14 0.08 -0.04 -0.28 -0.14 -0.53 -0.27 0.56 -0.38
10989 || orf19.357 || || || Ortholog(s) have role in inner mitochondrial membrane organization, mitochondrion inheritance, mitochondrion morphogenesis, negative regulation of proteolysis, protein folding, replicative cell aging || 1 -0.20 -0.31 -0.35 -0.37 0.77 0.49 0.03 0.03 0.11 -0.02 -0.22 0.04 -0.38 -0.25 0.78 -0.19
10990 || orf19.3813 || || || Ortholog of C. dubliniensis CD36 : Cd36_44340, C. parapsilosis CDC317 : CPAR2_302240, Candida tenuis NRRL Y-1498 : CANTEDRAFT_105331 and Debaryomyces hansenii CBS767 : DEHA2E03454g || 1 -0.16 -0.46 -0.49 -0.42 0.69 0.25 0.05 -0.24 0.02 -0.38 -0.35 -0.44 0.08 0.07 0.87 -0.63
10991 || orf19.2892 || || || Ortholog of C. dubliniensis CD36 : Cd36_45910, C. parapsilosis CDC317 : CPAR2_501110, Candida tenuis NRRL Y-1498 : CANTEDRAFT_119393 and Debaryomyces hansenii CBS767 : DEHA2E08976g || 1 -0.99 -0.99 -1.07 -0.86 0.40 0.61 -0.42 -0.42 -0.31 -0.32 -0.15 0.04 -0.30 -0.64 0.87 -1.24
10992 || orf19.3507 || MCR1 || || NADH-cytochrome-b5 reductase; soluble in hyphae; alkaline downregulated; farnesol, ketoconazole or flucytosine induced; protein present in exponential and stationary growth phase yeast; YNB biofilm induced; rat catheter biofilm repressed || 1 -0.53 -0.43 -0.70 0.06 -0.10 0.48 -0.16 -0.15 -0.19 -0.23 -0.23 -0.22 -0.08 -0.23 0.91 -0.58
10993 || orf19.3507 || MCR1 || || NADH-cytochrome-b5 reductase; soluble in hyphae; alkaline downregulated; farnesol, ketoconazole or flucytosine induced; protein present in exponential and stationary growth phase yeast; YNB biofilm induced; rat catheter biofilm repressed || 1 -0.05 -0.30 -0.32 -0.20 -0.00 0.38 -0.08 0.06 -0.06 -0.21 -0.09 -0.18 0.06 -0.18 0.71 -0.54
10994 || orf19.6790 || || || Ortholog(s) have mRNA binding activity, role in 3'-UTR-mediated mRNA destabilization, mitochondrion organization and cytoplasmic mRNA processing body, cytoplasmic stress granule, cytosol, perinuclear region of cytoplasm localization || 1 -0.44 -0.61 -0.05 -0.11 0.08 0.49 -0.43 -0.38 0.02 -0.21 -0.62 -0.06 0.08 -0.10 0.78 -0.97
10995 || orf19.6173 || STD1 || || Putative transcription factor; involved in control of glucose-regulated gene expression; repressed by Rgt1; Spider biofilm induced || 1 -0.45 -0.11 -0.04 0.00 0.11 0.14 -0.66 -0.44 -0.06 0.04 -0.34 -0.28 0.09 -0.30 0.46 -0.53
10996 || orf19.7119 || RAD3 || || Ortholog of S. cerevisiae Rad3; 5' to 3' DNA helicase, nucleotide excision repair and transcription, subunit of RNA polII initiation factor TFIIH and Nucleotide Excision Repair Factor 3 (NEF3) || 1 -0.25 -0.56 0.25 0.00 0.13 0.10 -0.35 -0.37 0.04 0.00 -0.05 -0.31 -0.47 -0.03 0.58 -0.50
10997 || orf19.6422 || SSY5 || || Ortholog(s) have serine-type endopeptidase activity, role in protein processing, response to amino acid and extrinsic to plasma membrane localization || 1 -0.04 -0.00 0.11 0.02 0.35 -0.31 -0.36 -0.41 -0.26 -0.56 -0.42 -0.31 0.11 -0.29 0.18 -0.48
10998 || orf19.6985 || TEA1 || || Putative transcription factor with zinc cluster DNA-binding motif; has similarity to S. cerevisiae Tea1p; Hap43p-repressed gene || 1 0.53 0.50 -0.20 -0.23 0.32 -0.08 -0.40 -1.05 -0.19 -1.14 -1.13 -0.44 0.76 -0.02 0.51 -0.22
10999 || orf19.5784 || AMO1 || || Putative peroxisomal copper amine oxidase || 1 -0.05 0.03 0.02 -0.22 1.03 -0.19 -0.31 -1.72 -0.44 -1.75 -1.83 -0.88 0.92 -0.76 0.23 -0.04
11000 || orf19.3360 || || || Protein of unknown function; flow model biofilm induced; Spider biofilm induced || 1 0.49 0.67 -0.09 0.10 0.84 0.41 0.03 -1.50 -0.80 -1.25 -1.15 -1.09 0.61 -0.27 -0.01 -0.22
11001 || orf19.5962 || HGT4 || || Glucose and galactose sensor; fermentation, filamentation, virulence roles; 20-member glucose transporter family; extended C terminus; high-glucose repressed; macrophage induced; flow model biofilm repressed; Spider biofilm induced || 1 -0.19 -0.26 -0.30 -0.20 0.75 -0.02 -0.32 -0.49 -0.66 -0.44 -0.52 -0.66 0.17 -0.24 0.24 -0.61
11002 || orf19.2747 || RGT1 || || Zn(II)2Cys6 transcription factor; transcriptional repressor involved in the regulation of glucose transporter genes; ortholog of S. cerevisiae Rgt1; mutants display decreased colonization of mouse kidneys || 1 0.19 0.46 -0.64 -0.29 1.08 0.59 -0.59 -0.52 -0.76 -0.65 -1.03 -0.62 -0.54 -1.16 0.84 -0.71
11003 || orf19.7337 || || || Protein with a nischarin related domain and leucine rich repeats; Spider biofilm induced || 1 0.46 0.24 -0.29 -0.14 0.65 0.56 -0.66 -0.82 -0.62 -0.82 -0.50 -0.70 0.30 -0.56 0.05 -0.02
11004 || orf19.5306 || || || Ortholog of C. dubliniensis CD36 : Cd36_43820 and Candida albicans WO-1 : CAWG_03393 || 1 0.32 0.21 -1.16 -0.11 2.04 1.30 -0.37 -1.74 -2.17 -2.10 -1.49 -1.86 1.12 -2.05 1.32 -1.24
11005 || CaalfMp09 || NAD2 || || Subunit 2 of NADH:ubiquinone oxidoreductase (NADH:ubiquinone dehydrogenase), a multisubunit enzyme complex (complex I) of the mitochondrial inner membrane that catalyzes the first step in mitochondrial respiration || 1 0.57 0.50 -0.81 -0.66 1.12 0.26 -0.22 -0.24 -0.95 -1.25 0.07 -0.98 0.52 -0.90 0.63 -0.61
11006 || orf19.6525 || || || S. cerevisiae ortholog Inp1 is a peripheral membrane protein of peroxisomes involved in peroxisomal inheritance; induced by Mnl1 under weak acid stress || 1 0.28 0.22 -0.02 -0.24 0.58 -0.15 0.03 -0.27 -0.25 -0.33 -0.32 -0.49 0.26 -0.47 0.30 -0.16
11007 || orf19.1349 || || || Ortholog of C. dubliniensis CD36 : Cd36_22470, Candida tropicalis MYA-3404 : CTRG_01829 and Candida albicans WO-1 : CAWG_05920 || 1 -0.06 0.06 -1.02 -0.32 1.56 0.17 -0.68 -1.00 0.14 -1.65 -0.70 -0.29 -0.06 -1.86 0.30 -0.71
11008 || orf19.5642 || || || Ortholog of S. cerevisiae Dif1; which regulates nuclear localization of Rnr2 and Rnr4; colony morphology-related gene regulation by Ssn6; induced in cyr1 mutant; Spider biofilm induced || 1 0.12 0.02 -0.82 -1.09 -0.13 -0.30 -0.27 -0.44 -0.85 -1.43 -0.16 -1.00 0.22 -0.98 0.08 -0.55
11009 || CaalfMp09 || NAD2 || || Subunit 2 of NADH:ubiquinone oxidoreductase (NADH:ubiquinone dehydrogenase), a multisubunit enzyme complex (complex I) of the mitochondrial inner membrane that catalyzes the first step in mitochondrial respiration || 1 0.12 0.26 -1.25 -1.25 0.76 -0.44 -0.12 -0.40 -1.64 -1.50 -0.26 -1.51 0.06 -1.09 0.36 -1.09
11010 || orf19.448 || CUE5 || || Predicted ubiquitin-binding protein; rat catheter biofilm repressed || 1 0.28 0.39 -0.49 -0.58 0.21 -0.44 -0.01 -0.13 -0.56 -0.59 -0.09 -0.44 -0.22 -0.15 0.33 -0.29
11011 || orf19.1370 || || || Protein of unknown function; expression regulated by white-opaque switch; repressed by alpha pheromone in SpiderM medium || 1 1.18 1.18 0.41 -0.59 0.08 -0.07 -0.87 -1.50 -0.11 -0.70 0.54 -1.77 0.76 -1.04
11012 || orf19.6547 || || || Ortholog of Candida albicans WO-1 : CAWG_05528 || 1 0.36 0.15 -0.11 0.08 0.07 0.32 0.11 0.02 -0.89 -1.33 -0.35 -1.44 0.31 -1.79 0.26 -1.12
11013 || orf19.4566 || || || Protein similar to S. cerevisiae Rot1p, which has roles in cytoskeletal dynamics and cell wall biosynthesis; predicted Kex2p substrate || 1 -0.23 0.02 0.22 -0.10 0.50 0.74 -0.10 0.11 -0.51 -0.37 0.00 -0.53 0.02 -0.70 0.09 -0.32
11014 || orf19.823 || || || Protein of unknown function; Spider biofilm induced || 1 0.46 0.17 -0.67 -0.53 0.76 2.06 -0.07 0.50 -0.67 -0.71 -0.20 -0.76 0.06 -0.99 0.65 -1.31
11015 || orf19.7140 || || || Putative catechol o-methyltransferase; stationary phase enriched protein; transcription upregulated in clinical isolates from HIV+ patients with oral candidiasis; Spider biofilm repressed || 1 0.03 0.02 -0.80 -0.11 0.77 0.87 -0.04 -0.17 -0.06 -0.67 0.30 0.16 0.07 -0.49 0.72 -0.55
11016 || orf19.5863 || || || Ortholog of C. dubliniensis CD36 : Cd36_84160, Candida tenuis NRRL Y-1498 : cten_CGOB_00085, Debaryomyces hansenii CBS767 : DEHA2B08404g and Pichia stipitis Pignal : PICST_67031 || 1 -0.25 -0.49 -0.91 -0.57 0.68 1.66 -0.28 -0.71 -1.22 -1.15 0.17 0.45 -0.21 -1.03 1.10 -1.04
11017 || orf19.5040 || || || Ortholog(s) have nucleocytoplasmic transporter activity, phospholipid binding, single-stranded DNA binding activity || 1 -0.10 -0.10 -0.30 -0.49 0.44 0.75 -0.06 -0.56 -0.86 -0.27 0.25 0.13 0.19 -0.37 0.37 -0.26
11018 || orf19.138 || FIG1 || || S. cerevisiae Fig1 ortholog; an integral membrane protein required for mating; role in thigmotropism; transcript is opaque-specific and a-specific; activated by Cph1 or alpha pheromone || 1 -0.44 -0.04 0.02 0.35 0.98 0.04 -0.74 -1.40 -0.06 0.34 0.58 -0.05 -0.77
11019 || orf19.823 || || || Protein of unknown function; Spider biofilm induced || 1 0.05 0.20 -1.10 -1.42 0.46 2.40 -1.04 -0.58 -3.45 -2.29 -1.31 0.51 0.16 -1.57 0.97 -0.92
11020 || orf19.5059 || GCS1 || || Gamma-glutamylcysteine synthetase; glutathione synthesis, required for virulence;induced in low iron, H2O2, Cd, or presence of human neutrophils; possibly adherence-induced; Spider and F-12/CO2 biofilm induced || 1 -0.16 -0.19 -0.94 -0.78 0.20 0.73 0.82 -0.24 -0.70 -0.43 -0.24 -0.33 0.21 -0.41 0.52 -0.28
11021 || orf19.5286 || YCP4 || || Putative flavodoxin; flow model, rat catheter and Spider biofilm repressed || 1 -0.12 -0.13 -0.34 -0.21 0.20 0.56 0.38 -0.05 -0.13 -0.66 -0.20 -0.41 0.65 0.07 0.26 -0.39
11022 || orf19.6848 || VPS16 || || Protein similar to S. cerevisiae Vps16p, which is involved in protein-vacuolar targeting; likely to be essential for growth, based on insertional mutagenesis; downregulated in biofilm or in azole-resistant strain that overexpresses MDR1 || 1 -0.03 0.01 -0.10 -0.31 0.49 0.14 0.00 -0.05 0.08 -0.09 -0.01 -0.01 0.25 -0.28 0.51 -0.30
11023 || orf19.3813 || || || Ortholog of C. dubliniensis CD36 : Cd36_44340, C. parapsilosis CDC317 : CPAR2_302240, Candida tenuis NRRL Y-1498 : CANTEDRAFT_105331 and Debaryomyces hansenii CBS767 : DEHA2E03454g || 1 0.16 0.12 -0.19 -0.46 0.53 0.14 0.05 0.14 -0.04 -0.14 -0.25 -0.15 0.16 -0.42 0.85 -0.33
11024 || orf19.7412 || MUB1 || || Predicted protein required for ubiquitination; role in meiosis, regulation of cell budding in S. cereviae; Spider biofilm induced || 1 0.07 0.24 -0.11 -0.31 0.48 0.09 -0.41 0.02 -0.68 0.06 0.04 0.10 0.32 -0.53 0.81 -0.31
11025 || orf19.5214 || VPS33 || || Ortholog(s) have ATP binding, phosphatidylinositol binding activity || 1 -0.18 -0.05 -0.34 -0.23 0.07 -0.00 -0.13 -0.24 -0.25 -0.14 -0.03 -0.17 -0.18 -0.87 0.42 -0.50
11026 || orf19.1247 || || || Ortholog of C. dubliniensis CD36 : Cd36_45230, C. parapsilosis CDC317 : CPAR2_500450, Candida tenuis NRRL Y-1498 : CANTEDRAFT_103249 and Debaryomyces hansenii CBS767 : DEHA2C07524g || 1 -0.03 0.15 -0.65 -0.55 0.09 -0.12 0.22 0.29 -0.37 -0.25 0.34 -0.18 -0.34 -0.99 0.32 -0.34
11027 || orf19.5472 || || || Protein of unknown function || 1 0.31 -0.31 -0.38 -0.02 0.30 0.09 -0.29 0.47 -0.43 -0.01 0.21 -0.54 0.01 -1.23 0.25 0.01
11028 || orf19.513 || || || Protein with a DNA-binding domain, similar to S. cerevisiae meiosis-specific transcription factor Ndt80p || 1 -0.06 -1.13 -0.33 -0.18 0.27 0.36 -0.02 0.54 -0.34 -0.75 -0.46 0.46 -0.83 -0.59 -0.09 0.22
11029 || orf19.399 || || || Putative serine/threonine protein kinase; possibly an essential gene, disruptants not obtained by UAU1 method || 1 -0.23 -0.48 -0.04 -0.17 0.03 0.09 -0.14 -0.41 0.13 -0.35 -0.06 -0.13 -0.19 -0.13 0.57 0.39
11030 || orf19.3412 || ATG15 || || Putative lipase; fungal-specific (no human or murine homolog); Hap43p-repressed gene || 1 -0.12 -0.23 -0.34 -0.40 -0.01 0.06 -0.29 -0.32 0.15 -0.30 -0.13 -0.51 -0.06 0.02 0.30 0.12
11031 || orf19.2175 || || || Putative mitochondrial cell death effector; induced by nitric oxide; Spider biofilm induced; rat catheter biofilm repressed || 1 -0.65 -0.63 -0.53 -0.53 -0.39 -0.63 -0.16 -0.08 -0.07 -0.49 -0.24 -0.99 -0.52 0.10 0.93 0.97
11032 || orf19.2175 || || || Putative mitochondrial cell death effector; induced by nitric oxide; Spider biofilm induced; rat catheter biofilm repressed || 1 -0.76 -1.08 -0.58 -0.72 -0.86 -0.77 0.10 0.23 0.14 -0.25 0.02 -1.13 -0.65 0.22 1.25 0.88
11033 || orf19.605 || || || Ortholog of Candida albicans WO-1 : CAWG_02087 || 1 -0.18 -0.82 -1.04 -0.31 0.17 -0.56 -0.19 0.26 -0.74 -0.24 -0.72 -0.47 -0.68 0.72 0.16
11034 || orf19.3425 || || || RING/FYVE/PHD zinc finger protein; Spider biofilm induced || 1 -0.10 -0.49 -0.45 -0.42 0.26 -0.54 -0.23 -0.48 -0.19 -0.07 -0.64 -0.33 -0.23 0.12 0.81 -0.12
11035 || orf19.4411 || HOS1 || || Histone deacetylase; similar to S. cerevisiae Hos1; has conserved deacetylation motif; slightly greater expression in white cells than in opaque cells || 1 -0.22 -0.18 -0.25 -0.14 -0.42 -0.32 -0.21 -0.48 -0.14 -0.27 -0.63 -0.30 -0.46 0.36 0.69 0.42
11036 || orf19.4411 || HOS1 || || Histone deacetylase; similar to S. cerevisiae Hos1; has conserved deacetylation motif; slightly greater expression in white cells than in opaque cells || 1 -0.15 -0.13 -0.20 0.01 -0.15 -0.20 -0.11 -0.33 -0.06 -0.45 -0.65 -0.25 -0.41 0.24 0.37 -0.00
11037 || orf19.7110 || || || Ortholog(s) have tRNA-specific adenosine-37 deaminase activity, role in tRNA modification and cytosol, nucleus localization || 1 -0.17 -0.19 -0.34 -0.16 0.15 0.04 -0.34 -0.38 0.10 -0.34 -0.38 -0.09 -0.27 0.31 0.10 0.01
11038 || orf19.3589 || SPO11 || || DNA endonuclease; required for genetic recombination between homologous chromosomes during the parasexual cycle; produced in mitotically dividing cells; similar to S. cerevisiae Spo11 which functions in recombination during meiosis || 1 -0.34 -1.04 -0.41 -0.79 0.63 0.10 -0.96 -0.75 -0.21 -0.48 -0.46 -0.03 -0.49 0.88 1.09 0.07
11039 || orf19.3425 || || || RING/FYVE/PHD zinc finger protein; Spider biofilm induced || 1 -0.18 -0.15 0.11 -0.38 0.20 -0.05 -0.26 -0.53 -0.17 0.05 -0.94 -0.02 -0.41 0.82 0.48 0.04
11040 || orf19.4332 || || || Ortholog of C. dubliniensis CD36 : Cd36_52800, C. parapsilosis CDC317 : CPAR2_303110, Candida tenuis NRRL Y-1498 : CANTEDRAFT_92321 and Debaryomyces hansenii CBS767 : DEHA2G07964g || 1 -0.17 0.01 0.24 -0.07 -0.13 -0.26 -0.08 -0.31 0.66 -0.09 -0.31 -0.06 -0.09 -0.34 -0.21 0.38
11041 || orf19.6670 || CAC2 || || Component of the chromatin assembly factor I (CAF-1); involved in regulation of white-opaque switching frequency; macrophage-induced || 1 -0.23 -0.28 0.10 0.09 -0.30 -0.06 -0.22 -0.25 0.58 0.16 0.01 0.40 0.05 -0.28 -0.42 0.36
11042 || orf19.1032 || SKO1 || || bZIP transcription factor; involved in cell wall damage response; represses the yeast-to-hypha transition; mutants are caspofungin sensitive; induced by osmotic stress via Hog1; induced by Mnl1 under weak acid stress || 1 -0.55 -0.41 0.12 -0.43 -0.44 0.04 -0.51 -0.24 0.71 -0.18 0.45 0.27 -0.26 -0.61 -0.49 -0.19
11043 || orf19.513 || || || Protein with a DNA-binding domain, similar to S. cerevisiae meiosis-specific transcription factor Ndt80p || 1 -0.63 -0.47 0.54 -0.42 -0.60 -1.19 -0.92 -0.29 2.00 -0.12 0.25 0.38 -0.30 -0.20 -0.19 -0.56
11044 || orf19.3280 || || || Ortholog of Candida albicans WO-1 : CAWG_01435 || 1 -0.42 0.05 -0.85 -0.30 -0.07 -0.53 -0.04 1.75 -0.05 0.01 -1.60 -0.19 -0.16
11045 || orf19.4678 || || || Predicted triglyceride lipase; Spider biofilm induced || 1 0.06 -0.06 -0.11 -0.03 0.16 -0.22 -0.06 -0.20 0.22 -0.03 0.34 0.42 -0.19 -0.07 0.19 -0.18
11046 || orf19.4900 || MNN12 || || Predicted alpha-1,3-mannosyltransferase activity with a role in protein glycosylation || 1 -0.21 -0.30 -0.64 -0.87 -0.13 -0.11 -0.32 -0.75 0.04 -0.67 0.54 0.98 -0.62 -0.54 0.08 -0.09
11047 || orf19.4900 || MNN12 || || Predicted alpha-1,3-mannosyltransferase activity with a role in protein glycosylation || 1 -0.09 -0.12 -0.29 -0.27 -0.12 -0.02 -0.31 -0.56 0.17 -0.50 0.49 1.02 -0.58 -0.46 -0.06 0.07
11048 || orf19.4900 || MNN12 || || Predicted alpha-1,3-mannosyltransferase activity with a role in protein glycosylation || 1 0.14 -0.10 -0.10 -0.59 0.03 -0.03 -0.28 -0.71 -0.04 -0.61 0.72 0.99 -0.54 -0.61 -0.11 0.19
11049 || orf19.5406 || || || Predicted plasma membrane associated protein phosphatase; required for normal filamentous growth; mRNA binds She3 and is localized to hyphal tips || 1 -0.56 -0.34 -0.16 -0.41 -0.46 -0.09 -0.17 -0.25 -0.12 -0.30 0.73 0.89 0.04 -0.30 -0.23 0.29
11050 || orf19.5578 || || || Ortholog of C. dubliniensis CD36 : Cd36_63050 and Candida albicans WO-1 : CAWG_05094 || 1 -0.39 -0.47 -0.18 -0.57 0.19 -0.12 -0.17 -0.02 -0.00 -0.45 0.49 0.73 0.27 -0.01 -0.51 0.85
11051 || orf19.99 || HAL21 || || Putative phosphoadenosine-5'-phosphate or 3'-phosphoadenosine 5'-phosphosulfate phosphatase; possible role in sulfur recycling; ortholog of S. cerevisiae Met22; predicted Kex2 substrate; F-12/CO2 biofilm induced || 1 -0.58 -0.48 -0.59 0.05 0.11 0.24 -0.50 -0.11 -0.24 0.09 0.59 0.59 -0.55 -0.29 -0.08 0.42
11052 || orf19.1716 || URA3 || || Orotidine-5'-phosphate decarboxylase; pyrimidine biosynthesis; gene used as genetic marker; decreased expression when integrated at ectopic chromosomal locations can cause defects in hyphal growth and virulence; Spider biofilm repressed || 1 -0.34 -0.32 -0.12 -0.09 -0.04 0.18 -0.38 -0.11 -0.08 0.30 0.47 0.53 -0.25 -0.35 0.17 0.56
11053 || orf19.261 || || || Ortholog(s) have dolichol kinase activity, role in protein glycosylation and endoplasmic reticulum membrane localization || 1 -0.30 -0.31 -0.32 -0.19 0.16 -0.02 -0.49 -0.28 0.02 0.38 0.12 0.41 -0.33 -0.76 0.03 0.32
11054 || orf19.1745 || || || Protein of unknown function; Hap43-repressed gene || 1 -0.36 -0.07 0.02 -0.38 0.10 0.18 -0.28 -0.27 0.06 -0.01 -0.14 0.48 -0.73 -0.51 -0.01 0.49
11055 || orf19.6992 || || || Predicted MFS membrane transporter, member of the drug:proton antiporter (12 spanner) (DHA1) family; Spider biofilm induced || 1 -1.36 -1.19 -0.54 -0.69 -0.64 0.44 -0.11 -1.12 0.39 -0.60 0.68 -0.18 -0.78 -0.46 -0.19 0.19
11056 || orf19.3937 || || || Ortholog(s) have protein phosphatase type 2A regulator activity, role in TOR signaling cascade, cellular response to nitrogen starvation and cytosol, nucleus localization || 1 -0.64 -0.54 -0.06 -0.09 -0.18 -0.07 -0.23 -0.57 0.09 0.06 0.23 0.21 -0.55 -0.09 -0.15 0.26
11057 || orf19.321 || || || Ortholog(s) have L-methionine transmembrane transporter activity and role in methionine import || 1 -0.52 -0.67 -0.28 0.20 -0.35 0.08 -0.50 -0.32 0.11 -0.28 0.35 0.13 -0.67 -0.14 -0.40 0.77
11058 || orf19.2046 || POT1-2 || || Putative peroxisomal 3-ketoacyl CoA thiolase; Hap43-repressed || 1 -0.76 -1.01 -0.19 -0.09 -0.26 0.31 -0.52 -0.34 0.16 -0.97 0.18 -0.09 -0.66 -0.03 -0.34 0.56
11059 || orf19.1341 || PRR2 || || Putative serine/threonine protein kinase; mutation confers resistance to 5-fluorocytosine (5-FC) || 1 -0.50 -0.68 0.13 -0.14 -0.43 0.42 -0.09 0.04 -0.01 0.09 0.50 0.18 -0.56 0.21 -0.49 0.21
11060 || orf19.3638 || PGA46 || || Putative GPI-anchored protein; secreted; fluconazole-induced || 1 -0.77 -0.81 0.07 -0.42 -0.18 0.75 -0.57 -0.05 0.89 0.46 0.41 -0.04 -1.04 -0.75
11061 || orf19.4621 || || || Ortholog(s) have cytoplasmic mRNA processing body localization || 1 -0.55 -0.48 0.26 -0.12 -0.43 0.01 0.19 -0.05 0.67 0.05 0.19 0.17 -0.39 -0.14 -0.50 0.32
11062 || orf19.6671 || LAP4 || || Protein similar to aminopeptidase I; mutation confers hypersensitivity to amphotericin B; transcript regulated in macrophage response; flow model biofilm induced || 1 -0.41 -0.36 0.14 -0.01 0.09 -0.22 -0.22 -0.07 0.39 -0.39 0.31 0.52 -0.40 -0.17 -0.33 0.30
11063 || orf19.540 || || || Has domain(s) with predicted palmitoyl-(protein) hydrolase activity and role in cellular protein modification process || 1 -0.43 -0.48 -0.03 -0.01 0.10 -0.34 -0.07 0.19 0.17 -0.47 0.21 0.08 -0.43 0.14 -0.58 0.40
11064 || orf19.2034 || || || Ortholog of C. parapsilosis CDC317 : CPAR2_212925, C. dubliniensis CD36 : Cd36_15840, Candida orthopsilosis Co 90-125 : CORT_0A12230 and Candida tropicalis MYA-3404 : CTRG_01156 || 1 -1.29 0.14 -0.33 -0.45 -0.56 -0.08 -0.27 -0.06 -0.28 -0.07 0.34 -0.10 -0.00 0.37
11065 || orf19.3404 || || || Protein of unknown function; transcription repressed by fluphenazine treatment || 1 -0.69 0.33 -0.29 -0.91 -0.45 0.50 -0.03 -0.40 0.28 0.39 0.19 0.09 0.19 -0.02 -0.11
11066 || orf19.3969 || SFL2 || || Transcription factor involved in regulation of morphogenesis; required for filamentous growth, for virulence in RHE model but not in mice; induced upon RHE infection but C. dubliniensis ortholog is not; Spider biofilm induced || 1 -1.00 -1.16 -0.21 -0.33 -1.18 1.74 0.41 -0.77 0.46 -0.67 0.63 0.20 0.56 0.32 0.71
11067 || orf19.2331 || ADA2 || || Zinc finger and homeodomain transcriptional coactivator; role in cell wall integrity and in sensitivity to caspofungin; required for the normal transcriptional response to caspofungin; required for yeast cell adherence to silicone substrate || 1 -0.08 -0.48 -0.47 -0.16 -0.67 0.40 0.16 -0.05 0.10 0.32 0.71 0.20 0.25 -0.23 0.24 0.47
11068 || orf19.2766 || || || Dubious open reading frame || 1 0.19 0.27 -0.51 0.22 0.23 0.76 -0.30 -0.34 -0.51 0.17 -0.52 -0.86 0.40
11069 || orf19.4871 || ERO1 || || Ortholog of S. cerevisiae Ero1; role in formation of disulfide bonds in the endoplasmic reticulum; fluconazole-induced; induced by Mnl1 under weak acid stress; Spider biofilm induced || 1 0.01 0.08 0.12 -0.61 0.17 0.07 0.44 -0.00 -0.27 -0.33 -0.51 -0.72 0.01 -0.16 -0.42 0.03
11070 || orf19.4936 || || || Dubious open reading frame || 1 -0.79 0.07 0.53 -1.70 0.04 0.17 -0.05 0.44 -0.20 -1.00 0.03 -0.37 0.32 0.10
11071 || orf19.7275 || FGR24 || || Protein encoded in retrotransposon Zorro2 with similarity to retroviral endonuclease-reverse transcriptase proteins; lacks an ortholog in S. cerevisiae; transposon mutation affects filamentous growth || 1 0.21 0.41 0.43 -2.32 -0.11 -0.18 0.81 -0.29 -0.37 0.31 -2.23 -0.38 0.35 0.34 0.76
11072 || orf19.7568 || || || Ortholog of S. cerevisiae : SPS4, C. glabrata CBS138 : CAGL0I09834g, C. dubliniensis CD36 : Cd36_35035, C. parapsilosis CDC317 : CPAR2_200810 and Candida tenuis NRRL Y-1498 : CANTEDRAFT_112327 || 1 0.67 -0.35 0.31 -1.88 0.31 0.39 0.03 1.37 0.13 0.15 0.31 -0.60 0.12 0.28 0.47 0.29
11073 || orf19.6288 || || || Dubious open reading frame || 1 0.43 -0.39 0.22 -1.62 -0.78 0.33 -0.09 0.12 -0.16 -0.82 -0.33 -0.05 -0.27 0.16 0.47
11074 || orf19.3637 || || || Dubious open reading frame || 1 0.57 0.13 -0.41 -1.39 -0.72 1.00 -0.88 0.73 0.40 -0.95 -0.26 0.09 0.30 0.07
11075 || orf19.3971 || || || Protein of unknown function; early-stage flow model biofilm induced || 1 0.09 0.10 -0.34 -0.85 0.17 0.52 0.13 0.44 0.12 -0.43 -0.37 -0.44 0.08 0.17 0.13 -0.41
11076 || orf19.3971 || || || Protein of unknown function; early-stage flow model biofilm induced || 1 0.12 0.02 -0.23 -0.66 0.26 0.76 0.14 -0.06 0.10 -0.65 -0.43 -0.55 0.26 0.00 0.02 -0.51
11077 || orf19.3140 || || || Ortholog of Candida albicans WO-1 : CAWG_03159 || 1 0.11 0.11 0.18 -0.61 0.28 -0.16 -0.20 0.02 0.04 -1.26 0.35 0.30 -0.29
11078 || orf19.1354 || UCF1 || || Upregulated by cAMP in filamentous growth; induced in high iron, decreased upon yeast-hypha switch; downregulation correlates with clinical fluconazole resistance; Ras1-regulated; Hap43-repressed; flow model biofilm induced || 1 -0.05 0.07 -0.03 -1.12 0.96 -0.52 -0.56 0.01 -2.04 -1.15 -2.07 0.76 0.67 0.02 -0.14
11079 || orf19.1354 || UCF1 || || Upregulated by cAMP in filamentous growth; induced in high iron, decreased upon yeast-hypha switch; downregulation correlates with clinical fluconazole resistance; Ras1-regulated; Hap43-repressed; flow model biofilm induced || 1 -0.09 0.07 -0.02 -1.28 1.15 0.89 -0.55 -0.51 0.00 -1.96 -0.85 -2.10 0.69 0.75 0.29 -0.06
11080 || orf19.1354 || UCF1 || || Upregulated by cAMP in filamentous growth; induced in high iron, decreased upon yeast-hypha switch; downregulation correlates with clinical fluconazole resistance; Ras1-regulated; Hap43-repressed; flow model biofilm induced || 1 -0.04 0.17 0.11 -1.23 0.92 -0.52 -0.43 0.07 -1.95 -0.95 -2.14 0.67 0.62 0.28 -0.00
11081 || orf19.1354 || UCF1 || || Upregulated by cAMP in filamentous growth; induced in high iron, decreased upon yeast-hypha switch; downregulation correlates with clinical fluconazole resistance; Ras1-regulated; Hap43-repressed; flow model biofilm induced || 1 -0.12 0.05 0.02 -1.26 0.99 -0.52 -0.54 -0.03 -2.05 -1.16 -2.16 0.52 0.66 0.21 0.04
11082 || orf19.1354 || UCF1 || || Upregulated by cAMP in filamentous growth; induced in high iron, decreased upon yeast-hypha switch; downregulation correlates with clinical fluconazole resistance; Ras1-regulated; Hap43-repressed; flow model biofilm induced || 1 -0.11 0.04 -0.05 -1.25 -0.60 -0.63 -0.05 -2.08 -1.12 -2.17 0.36 0.52 0.22 -0.02
11083 || orf19.1524 || SPR3 || || Septin; mutant has no obvious phenotype || 1 -0.25 0.34 0.26 -0.49 0.20 0.50 0.05 0.14 0.23 -0.92 0.55 0.04 0.23
11084 || orf19.6091 || RIM8 || || Beta-arrestin-like protein; involved in pH response; required for pathogenesis, activation of Rim101 and alkaline pH-induced hyphal growth; colony morphology-related gene regulation by Ssn6p negative feedback regulation target || 1 0.33 0.36 -0.02 -0.49 0.41 0.68 0.37 0.07 -0.17 -1.05 -0.25 -0.67 0.56 0.05 -0.29 -0.04
11085 || orf19.6529 || CDC34 || || Putative ubiquitin-protein ligase; transcript regulated by Nrg1 and Tup1, and by Gcn2 and Gcn4; rat catheter biofilm induced || 1 0.20 0.20 -0.28 -0.61 0.23 0.56 0.71 -0.06 0.16 -0.90 -0.09 -0.69 0.93 0.44 0.00 0.58
11086 || orf19.1616 || FGR23 || || Protein of unknown function; repressed by a1/alpha2 in white-phase cells, a-specific, alpha factor-induced; Hap43-repressed; flow model biofilm induced; Tn mutation affects filamentous growth; || 1 -0.05 -0.27 -0.28 -0.62 0.40 0.33 -0.21 -0.59 0.12 -1.39 -0.68 -0.40 0.88 0.44 -0.82 0.74
11087 || orf19.542 || HXK2 || || Hexokinase II; antigenic in humans; repressed by human neutrophils; Efg1-regulated; fluconazole-induced; gene regulation by Ssn6; present in exponential and stationary growth phase; flow model biofilm induced; Spider biofilm repressed || 1 -0.96 -1.05 -0.69 -2.04 -0.13 0.86 0.15 -0.22 0.80 -1.23 -0.52 -0.40 0.81 0.09 0.10 0.55
11088 || orf19.2987 || || || Ortholog(s) have role in cellular ion homeostasis, establishment or maintenance of cell polarity, mitochondrion inheritance, regulation of cardiolipin metabolic process and mitochondrial inner membrane, nucleus localization || 1 -0.12 -0.15 -0.61 -0.99 0.35 0.54 -0.04 -0.44 0.37 -0.76 -0.77 -0.21 0.05 0.19 -0.09 -0.26
11089 || orf19.7676 || XYL2 || || D-xylulose reductase; immunogenic in mice; soluble protein in hyphae; induced by caspofungin, fluconazole, Hog1 and during cell wall regeneration; Mnl1-induced in weak acid stress; stationary phase enriched; flow model biofilm induced || 1 -0.40 -0.40 0.11 -0.69 -0.12 0.78 0.46 -0.56 0.53 -1.78 -1.05 -0.34 0.32 -0.23 -0.02 0.02
11090 || orf19.7676 || XYL2 || || D-xylulose reductase; immunogenic in mice; soluble protein in hyphae; induced by caspofungin, fluconazole, Hog1 and during cell wall regeneration; Mnl1-induced in weak acid stress; stationary phase enriched; flow model biofilm induced || 1 -0.33 -0.29 -0.17 -0.84 0.01 0.78 0.45 -0.65 0.68 -1.79 -0.91 -0.68 0.39 -0.14 0.11 -0.12
11091 || orf19.6261 || BPH1 || || Ortholog of S. cerevisiae Bph1; a putative ortholog of human Chediak-Higashi syndrome protein and murine beige gene implicated in disease syndromes involving defective lysosomal trafficking; mutant is viable || 1 -0.17 -0.06 -0.27 -0.48 0.30 0.36 -0.09 -0.47 0.24 -0.74 -0.42 0.08 -0.06 0.06 0.08 0.34
11092 || orf19.6882 || OSM1 || || Putative flavoprotein subunit of fumarate reductase; soluble protein in hyphae; caspofungin repressed; stationary phase enriched protein; flow model biofilm induced; Spider biofilm repressed || 1 -0.11 -0.12 0.06 -1.47 0.24 0.91 0.03 -0.83 0.44 -2.04 -0.82 0.40 0.67 0.31 0.12 0.74
11093 || orf19.6882 || OSM1 || || Putative flavoprotein subunit of fumarate reductase; soluble protein in hyphae; caspofungin repressed; stationary phase enriched protein; flow model biofilm induced; Spider biofilm repressed || 1 -0.20 -0.29 -0.40 -1.78 0.26 0.46 -0.03 -0.91 -0.03 -2.24 -0.80 0.18 0.50 -0.06 0.04 0.70
11094 || orf19.5602 || BMT6 || || Beta-mannosyltransferase; beta-1,2-mannosylation of phospholipomannan; member of a 9-member family including Bmt1, Bmt2, Bmt3, and Bmt4 with roles in mannosylation of cell wall phosphopeptidomannan; flow model biofilm induced || 1 -0.22 -0.40 -0.27 -0.64 0.22 0.67 -0.18 -0.33 -0.01 -0.71 -0.36 -0.06 0.50 0.13 -0.06 0.31
11095 || orf19.6529 || CDC34 || || Putative ubiquitin-protein ligase; transcript regulated by Nrg1 and Tup1, and by Gcn2 and Gcn4; rat catheter biofilm induced || 1 -0.11 -0.14 -0.38 -0.56 0.12 0.55 0.21 -0.41 -0.07 -0.99 -0.30 -0.40 0.46 0.32 0.13 0.66
11096 || orf19.5251 || ZCF30 || || Predicted Zn(II)2Cys6 transcription factor; mutants are viable; repressed by fluphenazine; Spider biofilm induced || 1 0.01 -0.06 -0.33 -0.33 0.18 0.15 0.18 -0.14 -0.11 -0.59 -0.20 -0.04 0.14 0.16 0.36 0.14
11097 || orf19.1638 || || || Has domain(s) with predicted zinc ion binding activity, role in ER to Golgi vesicle-mediated transport, intracellular protein transport and COPII vesicle coat localization || 1 -0.12 -0.03 -0.28 -0.34 0.05 0.03 -0.04 -0.33 -0.01 -0.74 -0.37 -0.06 0.14 -0.09 0.49 0.25
11098 || orf19.3919 || || || RNI-like superfamily domain-containing protein; early-stage flow model biofilm induced; Spider biofilm induced || 1 -0.05 -0.37 -0.44 -0.77 0.24 0.56 0.25 -0.13 0.37 -0.54 -0.43 -0.02 0.11 0.02 0.62 0.28
11099 || orf19.6888 || || || Zn(II)2Cys6 domain transcription factor; regulated by Mig1 and Tup1; rat catheter and Spider biofilm induced || 1 -0.80 -0.83 -0.94 -0.78 0.07 0.46 0.43 -0.59 0.29 -0.77 -0.83 0.03 0.26 0.77 0.58 0.44
11100 || orf19.7510 || KIN2 || || Protein with similarity to S. cerevisiae Kin2p, transcription is positively regulated by Tbf1 || 1 -0.20 -0.25 -0.48 -0.36 0.05 0.07 0.15 0.05 0.00 -0.20 -0.12 0.01 0.06 0.29 0.51 0.16
11101 || orf19.2059 || || || Protein with homology to magnesium-dependent endonucleases and phosphatases; regulated by Sef1, Sfu1, and Hap43; Spider biofilm induced || 1 -0.21 -0.74 -0.76 -0.22 0.08 0.03 -0.22 -0.30 -0.29 -0.91 -0.85 -1.23 0.11 0.50 -0.24 0.84
11102 || orf19.5892 || || || Ortholog of S. cerevisiae Hul4; similar to hect domain E3 ubiquitin-protein ligases; Hap43-repressed gene || 1 -0.15 -0.13 0.10 -0.29 -0.07 -0.22 0.06 -0.16 -0.37 -0.66 -0.32 -0.44 0.05 -0.19 0.17 0.04
11103 || orf19.3589 || SPO11 || || DNA endonuclease; required for genetic recombination between homologous chromosomes during the parasexual cycle; produced in mitotically dividing cells; similar to S. cerevisiae Spo11 which functions in recombination during meiosis || 1 0.20 -0.28 0.22 -0.29 0.79 1.22 -0.27 -0.94 -0.49 -0.90 -0.47 -1.34 -0.38 0.36 0.83 0.02
11104 || orf19.3301 || || || Putative ubiquitin ligase complex component; induced by heavy metal (cadmium) stress; Hog1-induced; transcript induced by Mnl1p under weak acid stress; flow model biofilm induced; Spider biofilm induced || 1 -0.31 -0.46 0.38 -0.08 0.33 0.52 -0.03 -0.85 0.13 -0.42 0.17 -0.53 0.02 -0.32 0.25 -0.07
11105 || orf19.7092 || || || Putative NAD dependent epimerase/dehydratase family protein; Spider biofilm repressed || 1 -0.17 0.06 0.01 -0.28 0.33 0.36 -0.09 -0.09 0.28 -0.28 0.06 -0.15 0.29 -0.05 -0.44 0.12
11106 || orf19.2000 || || || Ortholog(s) have DNA helicase activity, role in DNA replication initiation, donor selection, interstrand cross-link repair, mitotic sister chromatid cohesion, negative regulation of DNA recombination and cytosol, nucleus localization || 1 -0.12 -0.09 -0.10 -0.45 0.60 0.47 -0.15 -0.52 0.24 0.30 -0.26 -0.14 0.31 0.18 -0.82 0.01
11107 || orf19.5231 || || || Protein of unknown function; flow model biofilm induced || 1 -0.39 0.09 -0.27 -0.17 0.27 0.36 -0.51 -0.83 0.17 -0.25 -0.56 -0.56 0.58 0.25 -0.69 0.08
11108 || orf19.2819 || || || Ortholog of C. dubliniensis CD36 : Cd36_27570, C. parapsilosis CDC317 : CPAR2_801010, Candida tenuis NRRL Y-1498 : cten_CGOB_00198 and Debaryomyces hansenii CBS767 : DEHA2E09306g || 1 -0.16 -0.04 -0.85 -0.38 1.06 0.45 -0.55 -0.65 -0.25 -0.31 -0.23 -0.23 0.56 0.19 -0.37 0.39
11109 || orf19.5530 || NAB3 || || Putative nuclear polyadenylated RNA-binding protein; flucytosine repressed || 1 -0.15 -0.24 -0.32 -0.65 0.74 0.44 -0.18 -0.41 -0.16 0.04 -0.13 0.06 0.28 0.14 -0.11 0.30
11110 || orf19.4081 || || || Dubious open reading frame || 1 -0.18 -0.11 -0.60 -0.65 0.08 -0.68 -0.23 -0.73 -0.05 -0.35 -0.19 0.34 -0.20 0.81
11111 || orf19.7317 || UGA33 || || Zinc-finger transcription factor; similar to S. cerevisiae Uga3 which regulates gamma-aminobutyrate metabolism gene expression; required for yeast cell adherence to silicone substrate; rat catheter biofilm induced || 1 0.03 0.18 -0.06 -0.37 0.06 0.22 -0.38 -0.29 -0.29 -0.40 -0.23 0.19 0.03 0.26 -0.36 0.45
11112 || orf19.4893 || || || Ortholog of C. dubliniensis CD36 : Cd36_09630, C. parapsilosis CDC317 : CPAR2_805080, Candida tenuis NRRL Y-1498 : CANTEDRAFT_136811 and Debaryomyces hansenii CBS767 : DEHA2B12364g || 1 -0.27 0.00 -0.03 -0.22 0.19 0.26 -0.28 -0.23 0.29 -0.19 -0.40 0.17 0.17 0.29 0.12 0.19
11113 || orf19.701 || CFL11 || || Protein similar to ferric reductase Fre10p; flucytosine repressed; possibly adherence-induced; possibly an essential gene, disruptants not obtained by UAU1 method; rat catheter biofilm repressed || 1 -0.53 -0.14 0.83 -1.57 -0.46 0.70 -0.72 -0.26 -0.11 -0.66 -0.16 -0.19 -0.57 0.28 -0.05 0.06
11114 || orf19.7330 || || || Protein with a predicted heme oxygenase domain; Spider biofilm induced || 1 -0.10 -0.19 0.62 -1.66 1.04 1.32 -0.31 0.03 0.10 -1.05 -0.18 0.69 -0.32 -0.08 -0.74 -1.03
11115 || orf19.599 || || || Dubious open reading frame || 1 -0.48 0.24 0.58 -0.46 0.08 0.72 -0.03 0.05 -0.11 -0.46 0.14 0.08 -0.14 -0.01 -0.27 -0.01
11116 || orf19.7007 || || || Ortholog of C. dubliniensis CD36 : Cd36_70990 and Candida albicans WO-1 : CAWG_05464 || 1 -0.12 0.49 0.70 -0.32 -0.14 0.82 -0.09 -0.21 0.00 -0.18 -0.11 0.63 0.07 0.26 -0.05 -0.30
11117 || orf19.664 || || || Ortholog of C. dubliniensis CD36 : Cd36_10680, Debaryomyces hansenii CBS767 : DEHA2E14058g, Pichia stipitis Pignal : PICST_29620 and Spathaspora passalidarum NRRL Y-27907 : SPAPADRAFT_146037 || 1 -0.02 -0.10 -0.41 -0.13 -0.26 0.13 -0.34 -0.94 -0.15 -0.12 0.10 0.80 -0.64 0.62 -0.42
11118 || orf19.3543 || || || Dubious open reading frame || 1 0.10 0.38 -0.52 -0.34 -0.16 -0.91 0.36 0.02 0.35 -0.79 0.06 0.12
11119 || orf19.7194 || || || Protein required for virulence in reconstituted human epithelium (RHE) model of ex vivo infection; decreased transcription is observed upon fluphenazine treatment; induced upon adherence to polystyrene || 1 0.28 0.06 -0.22 -0.15 -0.29 0.19 -0.06 -0.49 -0.40 0.61 -0.25 0.17 -0.14 0.09 -0.07 -0.26
11120 || orf19.721 || || || Ortholog(s) have polynucleotide 5'-hydroxyl-kinase activity || 1 0.14 0.29 -0.33 -0.26 -0.32 0.26 -0.23 -0.89 -0.38 0.33 0.09 -0.00 0.25 -0.10 0.02 -0.03
11121 || orf19.2447 || || || Putative Type II phosphatidylinositol 4-kinase; Ssr1-repressed; flow model biofilm repressed || 1 0.44 0.20 -0.17 -0.51 -0.34 0.04 -0.33 -0.62 -0.09 0.29 -0.62 0.09 -0.44 -0.25 0.69 0.21
11122 || orf19.56 || ARG2 || || Putative enzyme of arginine biosynthesis; transcription of genes of arginine biosynthesis pathway, except for ARG2, is induced upon phagocytosis by macrophage || 1 0.24 0.04 -0.15 -0.28 -0.29 -0.29 0.20 -0.14 0.25 -0.42 -0.13 -0.10 -0.75 0.42 -0.53 0.52
11123 || orf19.3937 || || || Ortholog(s) have protein phosphatase type 2A regulator activity, role in TOR signaling cascade, cellular response to nitrogen starvation and cytosol, nucleus localization || 1 0.12 -0.30 0.05 -0.30 -0.15 -0.15 0.05 0.18 0.05 0.06 -0.20 0.14 -0.24 0.24 -0.09 0.44
11124 || orf19.6353 || || || Ortholog of Candida albicans WO-1 : CAWG_00172 || 1 -0.47 -0.91 -0.03 -0.33 -0.42 -0.04 0.04 0.22 0.75 -0.18 -0.80 0.43 -0.40 0.47 -0.55 0.86
11125 || orf19.2908 || || || Predicted oxidoreductase; rat catheter biofilm induced || 1 -0.32 -0.20 -0.06 -0.09 -0.31 0.07 -0.11 0.00 0.38 -0.44 -0.19 0.23 -0.12 0.32 -0.05 0.70
11126 || orf19.2958 || || || Planktonic growth-induced gene || 1 -0.19 -0.11 0.22 -0.30 -0.99 -0.60 -0.28 -0.23 0.50 -0.06 -0.58 -0.29 -0.08 0.50 -0.87 0.38
11127 || orf19.2958 || || || Planktonic growth-induced gene || 1 -0.10 -0.09 0.35 -0.39 -0.87 -0.34 -0.25 0.03 0.25 -0.27 -0.40 -0.43 -0.38 0.67 -0.74 0.55
11128 || orf19.2176 || IFM3 || || Protein with a 2-hydroxyacid dehydrogenase catalytic domain; Hap43-repressed; Plc1-regulated; overlaps orf19.2177 || 1 -0.14 0.02 0.32 0.23 -0.64 -0.18 -0.17 -0.07 0.41 -0.24 -0.34 -0.41 -0.11 0.54 -0.45 0.40
11129 || orf19.4577 || || || Ortholog(s) have GTPase activating protein binding, cAMP-dependent protein kinase inhibitor activity, signal transducer activity || 1 -0.18 -0.24 0.51 0.16 -0.35 -0.11 -0.17 -0.15 0.49 -0.37 -1.07 -0.00 -0.15 0.44 -0.57 0.42
11130 || orf19.4577 || || || Ortholog(s) have GTPase activating protein binding, cAMP-dependent protein kinase inhibitor activity, signal transducer activity || 1 -0.21 -0.23 -0.05 -0.28 -0.23 0.14 -0.21 -0.08 0.67 0.03 -0.72 -0.43 0.08 0.75 -0.41 0.21
11131 || orf19.7380 || || || Has domain(s) with predicted nucleic acid binding, nucleotide binding activity || 1 0.17 0.13 0.08 -0.37 0.19 -0.43 0.01 0.33 0.24 -0.53 -0.31 0.69 -0.62 0.18
11132 || orf19.2034 || || || Ortholog of C. parapsilosis CDC317 : CPAR2_212925, C. dubliniensis CD36 : Cd36_15840, Candida orthopsilosis Co 90-125 : CORT_0A12230 and Candida tropicalis MYA-3404 : CTRG_01156 || 1 -0.69 -0.67 0.70 -0.91 -0.41 -0.49 -0.21 0.11 -0.10 -0.04 -0.42 -0.29 -0.62 0.64 -0.20 -0.29
11133 || orf19.4996 || || || Ortholog(s) have cytoplasm, nucleus localization || 1 -0.60 -0.55 -0.31 -0.03 -0.70 -0.40 0.32 0.08 0.56 -0.18 -0.14 -0.03 0.27 0.64 -0.03 0.30
11134 || orf19.4996 || || || Ortholog(s) have cytoplasm, nucleus localization || 1 -0.35 -0.85 -0.57 -0.28 -0.23 -0.17 0.36 -0.04 0.56 -0.07 -0.65 -0.23 0.24 0.67 0.29 0.29
11135 || orf19.651 || LYP1 || || Putative permease; amphotericin B induced; flucytosine repressed; possibly an essential gene, disruptants not obtained by UAU1 method || 1 -0.54 -0.82 -0.53 -0.36 0.01 -0.43 0.40 0.11 0.54 -0.02 -0.38 0.08 -0.22 0.63 0.12 -0.32
11136 || orf19.651 || LYP1 || || Putative permease; amphotericin B induced; flucytosine repressed; possibly an essential gene, disruptants not obtained by UAU1 method || 1 -0.79 -0.80 -0.44 -0.16 -0.66 -0.64 0.33 -0.07 0.82 0.09 -0.93 0.07 0.05 0.61 -0.24 -0.39
11137 || orf19.6478 || YCF1 || || Putative glutathione S-conjugate transporter; MRP/CFTR-subfamily, ABC type transporter; human neutrophil-induced; oxidative stress-induced via Cap1; possible association with multidrug resistance; possibly essential; Spider biofilm induced || 1 -0.35 -0.37 -0.08 -0.08 -0.41 -0.10 0.34 -0.08 0.45 0.02 -0.52 0.01 0.04 0.25 0.28 -0.04
11138 || orf19.2262 || || || Protein similar to quinone oxidoreductases; induced by benomyl treatment, nitric oxide; oxidative stress-induced via Cap1; stationary-phase enriched protein; Spider biofilm induced || 1 -0.69 -0.76 -0.21 -0.17 -0.76 -0.17 0.40 -0.24 0.90 -0.25 -0.83 0.16 -0.23 0.03 0.54 -0.81
11139 || orf19.1375 || LEU42 || || Putative alpha-isopropylmalate synthase; fungal-specific; induced by human blood or polymorphonuclear cells; regulated by Gcn2 and Gcn4; stationary phase enriched protein; Spider biofilm induced || 1 -0.73 -0.64 -0.70 -0.89 0.13 0.06 0.66 0.13 0.91 -0.18 -0.45 -0.11 -0.34 0.02 0.54 -0.42
11140 || orf19.1580 || || || Protein of unknown function; Spider biofilm induced || 1 -0.70 -0.89 -0.64 -0.50 -0.15 -0.83 0.24 0.15 0.69 0.32 -1.08 -0.67 -0.19 0.30 0.90 -0.68
11141 || orf19.5942 || || || Zinc finger protein orthologous to S. cerevisiae Itt1; repressed by adherence to polystyrene; Spider biofilm induced || 1 -0.21 -0.33 -0.51 -0.53 -0.08 -0.17 -0.07 -0.13 0.56 0.21 -0.82 -0.29 -0.43 -0.00 0.50 -0.04
11142 || orf19.918 || CDR11 || || Putative transporter of PDR subfamily of ABC family; Gcn4-regulated; induced by Rim101 at pH 8; Spider biofilm induced || 1 -0.85 -0.92 -0.93 -0.26 0.08 0.50 0.24 0.11 1.01 -0.16 -1.40 -0.70 -0.16 0.59 -0.14 -0.69
11143 || orf19.6704 || || || Protein of unknown function; Hap43-repressed gene || 1 -0.49 -0.45 -0.20 -0.22 -0.06 0.05 0.15 -0.04 0.69 -0.56 -0.68 -0.37 0.16 0.19 -0.22 0.07
11144 || orf19.6690 || || || Protein of unknown function; Hap43-repressed gene || 1 -0.44 -0.38 -0.10 0.09 -0.01 0.14 -0.03 -0.09 0.54 -0.48 -0.58 -0.03 -0.13 0.31 -0.37 -0.18
11145 || orf19.3791 || FGR10 || || Putative asparaginase; lacks ortholog in S. cerevisiae; transposon mutation affects filamentous growth; Spider biofilm induced || 1 -0.57 -0.39 -0.04 -0.23 -0.28 0.03 -0.28 -0.28 0.50 -0.06 -0.59 0.08 0.09 0.09 -0.14 -0.11
11146 || orf19.3325 || || || Putative glycogen synthesis initiator; regulated by Efg1 and Efh1; Hog1-repressed; colony morphology-related gene regulation by Ssn6; induced by prostaglandins; flow model biofilm induced || 1 -0.84 -0.79 -0.11 -0.20 -0.65 0.46 -0.08 -0.29 0.33 -0.67 -0.78 0.05 0.20 0.45 0.27 0.30
11147 || orf19.5451 || || || Ortholog of Candida guilliermondii ATCC 6260 : PGUG_05321, Candida lusitaniae ATCC 42720 : CLUG_00887 and Candida albicans WO-1 : CAWG_02354 || 1 -0.97 -1.12 -0.31 -0.60 -0.72 0.06 0.05 -0.18 0.66 -1.27 -0.44 0.23 0.71 0.40 0.39 -0.07
11148 || orf19.5370 || || || Ortholog(s) have fungal-type vacuole membrane localization || 1 -0.32 -0.38 -0.34 -0.29 -0.26 -0.03 -0.03 -0.09 0.19 -0.56 0.01 0.08 0.13 0.04 0.08 -0.12
11149 || orf19.7463 || || || Ortholog(s) have role in ascospore wall assembly and ascospore wall, nuclear envelope localization || 1 0.19 -0.69 -0.19 0.02 -0.15 0.18 -0.01 -0.19 0.69 -0.43 -0.64 -0.19 0.11 -0.06 0.32 0.28
11150 || orf19.3915 || || || Putative metallodipeptidase; protein present in exponential and stationary growth phase yeast; Hog1-induced; Hap43-repressed; sumoylation target; Spider biofilm repressed || 1 -0.09 -0.05 -0.08 -0.32 -0.05 -0.12 0.28 -0.11 0.51 -0.15 -0.28 0.28 -0.43 -0.28 -0.15 0.17
11151 || orf19.4828 || || || WD repeat domain protein; Hap43-repressed gene; flow model biofilm induced || 1 -0.53 -0.48 0.07 -0.48 0.05 0.27 0.14 -0.29 0.60 -0.61 -0.53 0.35 -0.13 -0.12 -0.15 0.27
11152 || orf19.7331 || FCY24 || || Putative transporter; more similar to S. cerevisiae Tpn1, which is a vitamin B6 transporter, than to purine-cytosine permeases; transcription is regulated by Nrg1; Spider biofilm induced || 1 -0.47 -0.66 -0.04 -0.14 0.32 0.51 0.08 -0.13 0.92 -0.34 -0.70 0.63 -0.34 -0.06 -0.70 0.01
11153 || orf19.4984 || || || Has domain(s) with predicted chitin binding, chitinase activity and role in carbohydrate metabolic process, cell wall macromolecule catabolic process, chitin catabolic process || 1 -0.36 -0.45 0.06 -0.62 0.34 0.04 0.10 0.25 0.53 -0.29 0.08 -0.01 -0.24 -0.09 -0.26 0.21
11154 || orf19.2097 || || || Predicted DNA-dependent ATPase/helicase; Spider biofilm induced || 1 -0.04 -0.12 -0.20 -0.50 0.55 0.41 -0.03 -0.06 0.83 -0.03 -0.19 -0.26 -0.14 -0.04 -0.02 -0.09
11155 || orf19.7518 || ZCF38 || || Putative Zn(II)2Cys6 transcription factor || 1 -0.35 -0.53 -0.25 -0.33 0.24 0.57 0.19 0.12 0.83 0.09 -0.40 0.11 -0.10 0.06 0.04 -0.17
11156 || orf19.6043 || || || Ortholog(s) have mitochondrial membrane localization || 1 -0.09 -0.10 0.07 -0.02 0.13 0.44 0.34 0.25 0.67 0.09 -0.80 -0.08 -0.07 0.27 -0.17 -0.38
11157 || orf19.2097 || || || Predicted DNA-dependent ATPase/helicase; Spider biofilm induced || 1 0.29 -0.29 -0.57 -0.27 0.22 0.30 0.38 -0.00 1.13 -0.21 -0.84 -0.40 -0.29 0.21 -0.54 -0.34
11158 || orf19.5236 || || || Ortholog(s) have dehydrodolichyl diphosphate synthase activity, role in protein glycosylation and lipid particle localization || 1 -0.22 -0.29 -0.12 -0.50 0.35 -0.04 -0.47 0.18 0.78 0.13 -0.27 -0.25 -0.01 -0.01 -0.48 -0.02
11159 || orf19.4540 || UBC8 || || Predicted ubiquitin-conjugating enzyme that negatively regulates gluconeogenesis by mediating the glucose-induced ubiquitination of fructose-1,6-bisphosphatase; induced by alpha pheromone in SpiderM medium || 1 -0.61 -0.30 -0.13 -0.44 0.05 -0.27 -0.20 -0.25 0.57 -0.53 -0.29 0.10 0.23 -0.20 0.26 -0.06
11160 || orf19.1614 || MEP1 || || Ammonium permease; Mep1 more efficient permease than Mep2, Mep2 has additional regulatory role; 11 predicted transmembrane regions; low mRNA abundance; hyphal downregulated; flow model biofilm induced || 1 -0.47 -0.26 0.03 -0.23 -0.27 -0.11 -0.29 -0.50 0.48 -0.45 -0.51 -0.06 0.28 -0.55 0.42 0.49
11161 || orf19.2943.5 || || || Ortholog of Candida albicans WO-1 : CAWG_05543 || 1 -0.68 -0.28 -0.07 -1.07 -0.21 -0.50 0.50 0.57 -0.37 -0.40 -0.13 0.12 -0.66 0.23 1.42 -0.37
11162 || orf19.3736 || KAR4 || || Transcription factor; required for gene regulation in response to pheromones; ortholog of S. cerevisiae Kar4; role in karyogamy; opaque-specific, a-specific; induced by alpha factor || 1 -0.72 -0.16 -0.41 0.31 -0.33 0.03 0.46 0.06 -0.54 0.75 -0.93 0.38 -0.10 -0.35 1.95 -0.10
11163 || orf19.6818 || || || Ortholog(s) have cytosol, mitochondrion localization || 1 -0.18 -0.09 -0.22 0.11 -0.18 -0.00 0.15 0.21 -0.25 0.44 -0.17 0.08 -0.62 -0.09 0.38 -0.21
11164 || orf19.5894 || || || Ortholog of S. cerevisiae : YEL023C, C. glabrata CBS138 : CAGL0I03168g, C. dubliniensis CD36 : Cd36_84380, Candida tenuis NRRL Y-1498 : CANTEDRAFT_101635 and Pichia stipitis Pignal : PICST_19384 || 1 -0.58 -0.15 -0.47 -0.54 -0.56 -0.05 0.68 -0.00 -0.21 -0.53 -0.55 0.45 0.34 -0.70
11165 || orf19.605 || || || Ortholog of Candida albicans WO-1 : CAWG_02087 || 1 -0.54 -0.42 -0.54 -0.24 -0.16 -0.03 0.12 0.71 -0.02 -0.09 -0.35 0.50 -0.54 -0.38 0.19 -0.98
11166 || orf19.6280 || || || Dubious open reading frame || 1 -0.52 -0.42 -1.04 -0.36 1.10 0.22 0.39 -0.71 0.18 0.63 -0.38 0.77 -1.32
11167 || orf19.3671 || || || Dubious open reading frame || 1 -0.17 -0.38 -0.16 -0.31 -0.04 -0.46 0.31 -0.01 0.23 0.02 -0.02 0.18 -0.15 0.12 0.35 -0.52
11168 || orf19.2168.3 || || || Ortholog(s) have role in cellular protein localization, cytokinesis, site selection, endoplasmic reticulum inheritance, endoplasmic reticulum tubular network organization, nuclear pore complex assembly, vesicle-mediated transport || 1 -0.27 -0.88 -0.81 -0.26 -0.74 -0.41 0.29 0.78 -0.12 0.01 0.86 0.31 -0.39 -0.29 0.60 -0.67
11169 || orf19.88 || ILV5 || || Ketol-acid reductoisomerase; antigenic; regulated by Gcn4; GlcNAc, amino acid starvation (3-AT)-induced; macrophage-repressed protein; protein present in exponential and stationary phase; flow model and Spider biofilm repressed || 1 -0.80 -0.93 -0.61 -0.26 -0.42 -0.11 0.20 0.15 0.09 -0.33 -0.22 -0.37 -0.87 -0.78 0.46 -0.44
11170 || orf19.541 || || || Has domain(s) with predicted oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors activity || 1 -0.59 -0.35 -0.50 0.33 -0.34 0.03 0.53 0.03 0.79 0.04 -0.47 -0.35 -1.15 0.02 0.67 -0.26
11171 || orf19.88 || ILV5 || || Ketol-acid reductoisomerase; antigenic; regulated by Gcn4; GlcNAc, amino acid starvation (3-AT)-induced; macrophage-repressed protein; protein present in exponential and stationary phase; flow model and Spider biofilm repressed || 1 -0.55 -0.53 -0.25 0.11 -0.08 0.06 0.40 0.68 0.61 0.09 0.12 0.10 -0.44 0.10 0.68 -0.23
11172 || orf19.4735 || || || Ornithine cyclodeaminase family protein; Sef1, Sfu1, and Hap43-regulated; ortholog of S. cerevisiae YGL159W and S. pombe SPAP11E10.01; rat catheter biofilm induced || 1 -0.43 -0.97 -0.35 0.30 -0.20 -0.38 0.11 0.36 0.24 0.00 -0.35 0.17 -0.65 0.15 0.19 0.19
11173 || orf19.4144 || || || Predicted protein kinase; clade-associated gene expression || 1 -0.26 -0.17 0.05 -0.05 0.21 -0.14 -0.07 -0.08 0.31 0.13 -0.10 0.44 -0.63 0.27 0.31 0.28
11174 || orf19.6933 || || || Ortholog(s) have peptidyl-prolyl cis-trans isomerase activity, protein phosphatase type 2A regulator activity || 1 -0.43 -0.50 0.06 -0.17 -0.07 -0.25 -0.06 -0.16 0.23 0.18 0.05 0.31 -0.49 0.19 0.12 0.06
11175 || orf19.2970 || LYS2 || || Heterodimeric alpha-aminoadipate reductase large subunit; lysine biosynthesis; predicted binding sites for AMP and alpha-aminoadipate; inhibited by lys or thialysine; regulated by Gcn2 and Gcn4; Spider biofilm induced, flow model repressed || 1 -0.61 -0.51 -0.49 -0.17 0.11 -0.39 -0.24 -0.35 0.61 -0.21 -0.14 0.31 -0.78 0.18 0.51 0.16
11176 || orf19.7119 || RAD3 || || Ortholog of S. cerevisiae Rad3; 5' to 3' DNA helicase, nucleotide excision repair and transcription, subunit of RNA polII initiation factor TFIIH and Nucleotide Excision Repair Factor 3 (NEF3) || 1 -0.54 -0.56 -0.16 -0.13 0.14 0.37 -0.29 -0.30 -0.09 0.07 -0.02 0.29 -0.70 0.07 0.71 -0.07
11177 || orf19.5984 || || || Putative protein of unknown function; homozygous transposon insertion causes decreased colony wrinkling under filamentous growth-inducing conditions, but does not block true hyphal formation in liquid media || 1 -0.48 -0.73 -0.45 -0.30 -0.17 -0.22 -0.31 -0.39 -0.13 0.43 -0.12 0.53 -0.22 0.13 0.76 0.21
11178 || orf19.5214 || VPS33 || || Ortholog(s) have ATP binding, phosphatidylinositol binding activity || 1 -0.33 -0.47 -0.27 -0.38 -0.23 0.00 -0.25 -0.20 0.09 0.39 0.09 0.52 -0.12 -0.55 0.22 -0.32
11179 || orf19.7498 || LEU1 || || 3-isopropylmalate dehydratase; antigenic in humans; repressed in hyphae; alkaline repressed; upregulated by human whole blood or PMNs; regulated by Sef1, Sfu1, and Hap43; rat catheter biofilm induced, Spider biofilm repressed || 1 -1.72 -1.76 -1.48 -0.90 -0.97 -0.58 0.15 -0.27 0.13 0.37 0.71 0.82 -1.71 -1.05 1.51 -0.22
11180 || orf19.7498 || LEU1 || || 3-isopropylmalate dehydratase; antigenic in humans; repressed in hyphae; alkaline repressed; upregulated by human whole blood or PMNs; regulated by Sef1, Sfu1, and Hap43; rat catheter biofilm induced, Spider biofilm repressed || 1 -0.93 -1.15 -0.58 -0.04 -0.62 -0.31 -0.12 -0.34 0.09 0.16 0.24 0.72 -1.03 -1.22 1.35 0.04
11181 || orf19.7498 || LEU1 || || 3-isopropylmalate dehydratase; antigenic in humans; repressed in hyphae; alkaline repressed; upregulated by human whole blood or PMNs; regulated by Sef1, Sfu1, and Hap43; rat catheter biofilm induced, Spider biofilm repressed || 1 -1.08 -0.97 -0.47 0.09 -0.41 -0.11 0.37 -0.06 0.23 0.50 0.85 0.89 -1.07 -1.15 1.61 -0.03
11182 || orf19.7498 || LEU1 || || 3-isopropylmalate dehydratase; antigenic in humans; repressed in hyphae; alkaline repressed; upregulated by human whole blood or PMNs; regulated by Sef1, Sfu1, and Hap43; rat catheter biofilm induced, Spider biofilm repressed || 1 -0.96 -1.12 -0.47 0.08 -0.56 -0.28 0.39 -0.12 0.44 0.71 0.90 0.75 -0.88 -1.41 1.53 -0.31
11183 || orf19.7498 || LEU1 || || 3-isopropylmalate dehydratase; antigenic in humans; repressed in hyphae; alkaline repressed; upregulated by human whole blood or PMNs; regulated by Sef1, Sfu1, and Hap43; rat catheter biofilm induced, Spider biofilm repressed || 1 -0.59 -0.43 -0.35 -0.12 -0.42 -0.15 0.34 0.23 0.64 0.89 0.54 0.91 -0.53 -0.83 1.41 0.05
11184 || orf19.1977 || URA4 || || Dihydroorotase; protein present in exponential and stationary growth phase yeast cultures || 1 -0.34 -0.27 -0.43 -0.21 -0.40 -0.22 -0.05 0.30 0.02 0.31 0.26 0.63 -0.20 -0.43 0.37 0.30
11185 || orf19.4390 || || || Protein of unknown function; repressed by alpha pheromone in SpiderM medium; transcript induced by Mnl1 under weak acid stress || 1 -0.72 -0.55 -0.62 -0.28 0.18 -0.45 0.05 0.09 -0.29 0.45 0.74 0.80 -0.07 -0.97 0.71 -0.32
11186 || orf19.4390 || || || Protein of unknown function; repressed by alpha pheromone in SpiderM medium; transcript induced by Mnl1 under weak acid stress || 1 -0.30 -0.07 -0.27 -0.11 0.18 -0.19 -0.12 0.53 -0.18 0.43 0.73 1.03 -0.17 -0.77 0.58 0.22
11187 || orf19.6379 || || || Ortholog of C. dubliniensis CD36 : Cd36_33820, C. parapsilosis CDC317 : CPAR2_206210, Candida tenuis NRRL Y-1498 : CANTEDRAFT_92567 and Debaryomyces hansenii CBS767 : DEHA2E06138g || 1 -0.31 -0.49 -0.25 -0.14 -0.19 0.11 -0.05 0.29 -0.36 -0.19 0.55 0.77 0.10 -0.57 0.54 0.02
11188 || orf19.776 || || || Ortholog(s) have role in meiotic sister chromatid cohesion, protein localization to chromosome, centromeric region, reciprocal meiotic recombination, synaptonemal complex assembly || 1 0.06 -0.78 -0.11 -0.02 -1.05 -0.92 -0.80 -2.65 -0.32 -0.34 0.46 0.38 -2.25 1.00 1.88
11189 || orf19.6897 || || || Protein of unknown function || 1 -0.48 -0.00 -0.48 -0.04 -0.12 -0.53 -0.06 0.15 -0.27 -0.31 0.02 -0.04 -0.34 -0.69 0.40 0.28
11190 || orf19.5617 || || || Ortholog(s) have methylated histone residue binding, transcription factor binding activity || 1 -0.21 -0.24 -0.68 -0.94 -0.49 -0.78 -0.08 0.04 -0.46 -1.04 0.02 -0.67 -0.11 -0.69 -0.19 -0.01
11191 || orf19.5411 || || || Ortholog(s) have NEDD8 ligase activity, role in protein neddylation, regulation of mitotic cell cycle and cytosol, nucleus localization || 1 -0.33 -0.41 -0.85 -0.79 0.03 -0.70 -0.33 -0.37 -0.94 -0.74 -0.01 -0.31 0.01 -0.38 0.33 0.20
11192 || orf19.1264 || CFL2 || || Oxidoreductase; iron utilization; Sfu1/Sef1/Hap43/Nrg1/Tup1/Rim101 regulated; alkaline/low iron/fluphenazine/ciclopirox olamine, flucytosine, fluconazole, Spider/flow model/rat catheter biofilm induced; caspofungin/amphotericin B repressed || 1 0.62 -1.42 -3.94 -2.47 0.09 -2.72 -0.10 -0.82 -4.11 -3.85 0.51 -2.23 -1.06 -0.17 1.83
11193 || orf19.1264 || CFL2 || || Oxidoreductase; iron utilization; Sfu1/Sef1/Hap43/Nrg1/Tup1/Rim101 regulated; alkaline/low iron/fluphenazine/ciclopirox olamine, flucytosine, fluconazole, Spider/flow model/rat catheter biofilm induced; caspofungin/amphotericin B repressed || 1 -0.78 -0.30 -3.43 -3.75 -0.32 -2.18 -0.42 -0.33 -3.52 -3.38 0.84 -1.63 -1.22 -4.35 0.40 2.33
11194 || orf19.4215 || FET34 || || Multicopper ferroxidase; induced by low iron, ciclopirox olamine, ketoconazole, hypoxia; alkaline induced by Rim101; repressed in fluconazole-resistant isolate; Sfu1, Hog1 repressed; complements S. cerevisiae fet3; Spider biofilm induced || 1 -0.51 -0.25 -1.90 -2.12 -0.53 -1.89 -0.64 -0.48 -2.53 -2.97 0.70 -0.53 -0.02 -2.56 -0.20 2.11
11195 || orf19.1264 || CFL2 || || Oxidoreductase; iron utilization; Sfu1/Sef1/Hap43/Nrg1/Tup1/Rim101 regulated; alkaline/low iron/fluphenazine/ciclopirox olamine, flucytosine, fluconazole, Spider/flow model/rat catheter biofilm induced; caspofungin/amphotericin B repressed || 1 -0.48 -0.92 -1.49 -1.55 -0.00 -1.91 -0.36 -0.19 -1.59 -2.49 -0.02 -1.60 0.17 -2.86 -0.54 1.66
11196 || orf19.4215 || FET34 || || Multicopper ferroxidase; induced by low iron, ciclopirox olamine, ketoconazole, hypoxia; alkaline induced by Rim101; repressed in fluconazole-resistant isolate; Sfu1, Hog1 repressed; complements S. cerevisiae fet3; Spider biofilm induced || 1 -1.64 -1.64 -2.13 -2.73 -1.28 -2.73 -2.69 -1.90 -4.44 -3.95 1.36 -1.12 -2.22 -4.72 -0.77 1.77
11197 || orf19.4215 || FET34 || || Multicopper ferroxidase; induced by low iron, ciclopirox olamine, ketoconazole, hypoxia; alkaline induced by Rim101; repressed in fluconazole-resistant isolate; Sfu1, Hog1 repressed; complements S. cerevisiae fet3; Spider biofilm induced || 1 -0.23 -0.36 -0.01 -0.31 -0.38 -1.30 -0.50 -0.43 -1.25 -2.05 0.78 -0.63 -0.35 -2.67 -0.10 1.84
11198 || orf19.4215 || FET34 || || Multicopper ferroxidase; induced by low iron, ciclopirox olamine, ketoconazole, hypoxia; alkaline induced by Rim101; repressed in fluconazole-resistant isolate; Sfu1, Hog1 repressed; complements S. cerevisiae fet3; Spider biofilm induced || 1 0.78 0.36 -0.72 -1.15 0.41 -1.37 -0.68 -0.55 -1.07 -2.99 1.20 -0.63 0.52 -2.85 -0.02 2.27
11199 || orf19.5406 || || || Predicted plasma membrane associated protein phosphatase; required for normal filamentous growth; mRNA binds She3 and is localized to hyphal tips || 1 -0.20 -0.34 -1.12 -0.90 -0.13 -0.37 -0.33 -0.27 -0.88 -1.02 1.12 0.19 0.09 -0.89 0.31 0.41
11200 || orf19.3006 || GGA2 || || Protein involved in Golgi trafficking; rat catheter and Spider biofilm repressed || 1 -0.12 -0.16 -0.49 -0.22 -0.16 -0.42 0.06 0.12 -0.38 -0.42 0.59 0.08 -0.04 -0.48 0.29 0.40
11201 || orf19.5674 || PGA10 || || GPI anchored membrane protein; utilization of hemin and hemoglobin for Fe in host; Rim101 at ph8/hypoxia/ketoconazole/ciclopirox/hypha-induced; required for RPMI biofilm formation, Bcr1-induced in a/a biofilm; rat catheter biofilm repressed || 1 0.07 0.25 -1.09 -0.90 0.06 -0.06 -0.53 -0.70 -1.14 -2.66 0.49 0.13 0.14 -1.17 0.44 1.76
11202 || orf19.6448 || || || Protein of unknown function; Spider biofilm repressed || 1 0.10 0.16 -0.40 -0.44 0.23 -0.09 -0.22 -0.30 -0.89 -0.69 0.15 -0.32 -0.02 -0.21 0.17 0.38
11203 || orf19.6595 || RTA4 || || Protein similar to S. cerevisiae Rsb1p, involved in fatty acid transport; transposon mutation affects filamentous growth; alkaline downregulated; caspofungin induced; possibly an essential gene; Hap43p-repressed || 1 0.00 -0.34 -0.04 -0.44 -0.13 -0.24 -0.21 -0.06 -0.79 -0.70 -0.11 -0.05 -0.55 -0.47 -0.05 0.67
11204 || orf19.4903 || || || Ortholog(s) have endoplasmic reticulum localization || 1 0.14 0.10 -0.28 -0.44 -0.35 -0.15 -0.32 -0.25 -0.47 -0.27 0.55 0.12 -0.59 -0.60 -0.27 0.24
11205 || orf19.6202 || RBT4 || || Pry family protein; required for virulence in mouse systemic/rabbit corneal infections; not filamentation; mRNA binds She3, is localized to hyphal tips; Hap43-induced; in both yeast and hyphal culture supernatants; Spider biofilm induced || 1 -0.64 -0.81 -0.92 -0.01 -0.86 -1.14 -1.10 -0.85 -1.10 -0.61 0.60 0.60 -2.07 -2.20 -0.76 0.02
11206 || orf19.6202 || RBT4 || || Pry family protein; required for virulence in mouse systemic/rabbit corneal infections; not filamentation; mRNA binds She3, is localized to hyphal tips; Hap43-induced; in both yeast and hyphal culture supernatants; Spider biofilm induced || 1 -0.51 -0.81 -0.63 0.08 -1.03 -0.80 -0.97 -0.76 -1.05 -0.84 0.69 0.62 -1.64 -2.33 -0.75 -0.11
11207 || orf19.2602 || OPT1 || || Oligopeptide transporter; transports 3-to-5-residue peptides; alleles are distinct, one has intron; suppresses S. cerevisiae ptr2-2 mutant defects; induced by BSA or peptides; Stp3p, Hog1p regulated; flow model biofilm induced || 1 -0.52 -0.92 -0.35 -0.44 -1.64 -1.89 -0.60 -0.65 -0.57 -1.70 0.69 0.52 -1.16 -2.26 -0.67 0.29
11208 || orf19.2602 || OPT1 || || Oligopeptide transporter; transports 3-to-5-residue peptides; alleles are distinct, one has intron; suppresses S. cerevisiae ptr2-2 mutant defects; induced by BSA or peptides; Stp3p, Hog1p regulated; flow model biofilm induced || 1 -0.86 -1.16 -1.03 -1.14 -1.89 -2.74 -0.66 -0.98 -1.25 -1.82 0.57 1.17 -1.63 -2.15 -1.51 0.79
11209 || orf19.2584 || OPT9 || || Probable pseudogene similar to fragments of OPT1 oligopeptide transporter gene; decreased expression in hyphae compared to yeast-form cells; transcriptionally induced upon phagocytosis by macrophage || 1 -0.84 -1.08 -1.45 -1.43 -2.04 -2.93 -0.86 -0.98 -1.24 -2.03 0.64 1.08 -1.64 -2.25 -1.51 0.72
11210 || orf19.2584 || OPT9 || || Probable pseudogene similar to fragments of OPT1 oligopeptide transporter gene; decreased expression in hyphae compared to yeast-form cells; transcriptionally induced upon phagocytosis by macrophage || 1 -0.60 -0.86 -0.95 -0.92 -1.34 -2.19 -0.94 -0.77 -0.60 -1.75 0.72 1.22 -0.86 -1.94 -1.21 0.36
11211 || orf19.2583.2 || || || Pseudogene; formerly an ORF Predicted by Annotation Working Group || 1 -0.71 -0.80 -1.04 -1.63 -0.75 -2.01 -0.75 -0.77 -1.82 -1.97 1.04 1.69 -1.06 -2.38 -0.59 0.87
11212 || orf19.2583.1 || || || Pseudogene; formerly an ORF Predicted by Annotation Working Group || 1 -1.23 -1.39 -2.94 -2.64 -1.01 -2.65 -0.93 -1.87 -2.63 -2.94 1.49 1.75 -1.64 -3.38 -0.98 1.14
11213 || orf19.3447 || || || Ortholog(s) have mannosyltransferase activity, role in ER-associated ubiquitin-dependent protein catabolic process, GPI anchor biosynthetic process, protein processing and endoplasmic reticulum localization || 1 -0.32 -0.29 -0.65 -0.54 -0.49 -0.59 -0.03 -0.36 -0.47 -0.29 -0.26 0.16 -0.36 -0.62 0.05 0.63
11214 || orf19.5306 || || || Ortholog of C. dubliniensis CD36 : Cd36_43820 and Candida albicans WO-1 : CAWG_03393 || 1 -0.46 -1.01 -1.57 -0.90 -1.61 0.29 -0.57 -0.67 -0.26 -0.58 1.71 -0.25 -1.52 -0.45 0.83
11215 || orf19.4322 || DAP2 || || Putative dipeptidyl aminopeptidase; transcriptionally regulated during macrophage response || 1 -0.17 -0.24 -0.45 -0.22 -0.92 -0.45 -0.24 -0.42 -0.10 0.15 0.23 0.73 -0.36 -0.43 -0.02 0.74
11216 || orf19.5406 || || || Predicted plasma membrane associated protein phosphatase; required for normal filamentous growth; mRNA binds She3 and is localized to hyphal tips || 1 0.11 -0.31 -0.73 -0.60 -0.84 -0.41 -0.70 -0.89 -0.49 -0.35 0.34 0.61 -0.19 -0.61 -0.40 0.76
11217 || orf19.2479 || UGA4 || || Putative gamma-aminobutyric acid/polyamine permease; nitrogen catabolite repressed gene, induced in absence of preferred N sources; transcriptionally induced upon phagocytosis by macrophage; gene regulation by nitrogen source requires Gat1p || 1 0.15 -0.71 -0.04 -0.92 -0.30 -0.14 -0.15 -0.50 -0.58 -0.05 -0.56 -0.25 -0.09 -0.02 -0.10 1.44
11218 || orf19.6927 || PEP8 || || Protein similar to S. cerevisiae Pep8p, which is involved in retrograde transport; transposon mutation affects filamentous growth || 1 -0.02 -0.08 -0.06 -0.15 -0.12 -0.24 -0.09 -0.11 -0.17 -0.42 -0.16 -0.11 -0.38 -0.04 -0.07 0.43
11219 || orf19.2108 || SOD6 || || Copper- and zinc-containing superoxide dismutase; gene family includes SOD1, SOD4, SOD5, and SOD6; gene may contain an intron; Hap43-repressed; flow model and rat catheter biofilm induced || 1 0.02 0.07 -0.06 -0.77 0.12 -0.25 -0.21 -0.22 -0.19 -1.38 -0.70 -0.27 -0.62 0.12 -0.10 1.18
11220 || orf19.2108 || SOD6 || || Copper- and zinc-containing superoxide dismutase; gene family includes SOD1, SOD4, SOD5, and SOD6; gene may contain an intron; Hap43-repressed; flow model and rat catheter biofilm induced || 1 0.06 0.38 -0.38 -1.87 0.06 0.26 -0.56 -1.06 -0.53 -1.31 -0.18 -0.70 -0.75 -0.09 0.07 1.93
11221 || orf19.4170 || CSP2 || || Putative cell wall associated protein; C. albicans and C. dubliniensis specific gene highly induced during chlamydospore development in both species; localized to chlamydospore cell wall; Hap43-repressed; Spider biofilm induced || 1 -0.59 -0.29 -0.55 -1.10 -0.20 0.14 -0.15 -0.74 0.01 -1.14 -0.43 -0.56 -0.80 -1.09 -1.00 1.79
11222 || orf19.4170 || CSP2 || || Putative cell wall associated protein; C. albicans and C. dubliniensis specific gene highly induced during chlamydospore development in both species; localized to chlamydospore cell wall; Hap43-repressed; Spider biofilm induced || 1 -0.51 -0.61 -1.59 -1.07 -0.18 0.06 0.34 -0.62 -0.22 -0.60 -0.25 -0.58 -0.38 -0.99 -0.70 1.33
11223 || orf19.1357 || FCY21 || || High affinity, high capacity, hypoxanthine-adenine-guanine-cytosine/H+ symporter; similar to S. cerevisiae Fcy2; mutation confers resistance to 5-fluorocytosine (5-FC); flow model biofilm induced || 1 -0.58 -0.42 -0.73 -0.87 -0.47 -0.28 0.25 -0.48 -0.17 -0.46 0.15 0.10 0.53 -0.12 -0.53 0.75
11224 || orf19.1357 || FCY21 || || High affinity, high capacity, hypoxanthine-adenine-guanine-cytosine/H+ symporter; similar to S. cerevisiae Fcy2; mutation confers resistance to 5-fluorocytosine (5-FC); flow model biofilm induced || 1 -0.40 -0.37 -0.20 -0.20 -0.39 -0.41 -0.08 -0.39 -0.11 -0.54 -0.05 0.18 0.41 -0.17 -0.48 0.72
11225 || orf19.3433 || OYE23 || || Putative NAPDH dehydrogenase; induced by nitric oxide, benomyl; oxidative stress-induced via Cap1; Hap43p-repressed; rat catheter biofilm induced || 1 -0.15 -0.02 0.01 -0.98 -0.64 -0.55 -0.10 -0.53 -0.39 -1.11 0.03 0.85 -0.18 -0.44 0.09 1.66
11226 || orf19.97 || CAN1 || || Basic amino acid permease; complements lysine transport mutation; 10 predicted transmembrane regions, 3 predicted N-glycosylation sites; phagocytosis by macrophages induces transcript; rat catheter, Spider and flow model biofilm induced || 1 -0.51 -0.48 -0.08 0.13 -0.86 -1.03 0.39 -0.57 -0.20 -1.22 -0.17 0.25 -0.21 -0.19 -0.64 1.50
11227 || orf19.4524 || ZCF24 || || Predicted Zn(II)2Cys6 transcription factor; caspofungin induced; Hap43-repressed || 1 0.01 -0.21 0.11 -0.27 -0.62 -0.23 0.01 -0.43 0.11 -0.63 -0.64 0.06 -0.20 0.13 -0.31 0.57
11228 || orf19.1729 || || || Putative transcription factor with zinc finger DNA-binding motif || 1 -0.13 -0.34 0.01 -0.36 -0.60 -0.11 -0.17 -0.23 0.09 -0.66 -0.11 0.08 -0.04 -0.26 -0.43 0.41
11229 || orf19.1364 || || || Ortholog of S. pombe Stm1 G-protein coupled receptor; PQ-loop domains; constitutive expression independent of MTL or white-opaque status; Hap43-repressed || 1 -0.20 -0.27 0.19 -0.25 -0.44 -0.05 0.12 -0.53 0.04 -0.65 -0.12 0.25 0.01 -0.05 -0.15 0.07
11230 || orf19.6980 || || || Has domain(s) with predicted ATP binding, protein tyrosine kinase activity and role in protein phosphorylation || 1 0.33 0.02 0.06 -0.39 -0.41 -0.30 -0.35 -0.54 -0.02 -0.56 -0.09 0.17 -0.54 -0.43 -0.04 0.10
11231 || orf19.5970 || || || Putative DNA repair helicase; transcriptionally induced by interaction with macrophage; fungal-specific (no human or murine homolog) || 1 -0.01 0.00 -0.14 -0.27 -0.39 -0.36 0.05 -0.21 -0.05 0.01 -0.22 -0.00 -0.05 -0.08 -0.11 0.14
11232 || orf19.3231 || CDC27 || || Putative ubiquitin-protein ligase; periodic mRNA expression, peak at cell-cycle S/G2 phase || 1 -0.04 -0.04 -0.38 -0.28 -0.71 -0.51 -0.06 -0.22 -0.35 0.00 -0.74 -0.03 -0.10 -0.12 -0.17 0.13
11233 || orf19.4735 || || || Ornithine cyclodeaminase family protein; Sef1, Sfu1, and Hap43-regulated; ortholog of S. cerevisiae YGL159W and S. pombe SPAP11E10.01; rat catheter biofilm induced || 1 0.22 0.54 -0.50 -0.63 -0.30 -0.42 -0.18 -0.04 -0.14 -0.16 -0.74 0.15 -0.04 -0.07 0.19 0.05
11234 || orf19.2907 || PGA42 || || Putative GPI-anchored adhesin-like protein; decreased transcription is observed in azole-resistant strains that overexpress CDR1 and CDR2 or MDR1 || 1 0.15 0.14 -0.50 -0.09 -0.83 -0.05 -0.05 -0.32 -0.29 -0.39 -0.57 -0.09 0.14 0.40
11235 || orf19.1553 || ENT3 || || Putative epsin; induced during the mating process; transcript is upregulated in an RHE model of oral candidiasis || 1 0.04 0.01 -0.28 -0.18 -0.12 -0.27 -0.17 0.12 -0.25 0.09 -0.05 0.03 -0.29 -0.02 0.13 0.10
11236 || orf19.7507 || || || Ortholog of C. dubliniensis CD36 : Cd36_25310, Pichia stipitis Pignal : PICST_30877, Candida tropicalis MYA-3404 : CTRG_01053 and Candida lusitaniae ATCC 42720 : CLUG_02644 || 1 -0.05 -0.17 -0.84 -0.45 -0.16 -0.73 0.24 0.49 -0.37 -0.33 -0.06 -0.06 -0.25 -0.06 -0.25 0.52
11237 || orf19.5190 || || || Ortholog of Candida albicans WO-1 : CAWG_05610 || 1 0.08 -0.67 -1.26 0.00 -0.08 0.91 -0.87 -0.55 0.78 0.08 -0.39 1.22
11238 || orf19.4740 || || || Ortholog(s) have aminoacyl-tRNA hydrolase activity, role in mitochondrial translation and mitochondrion localization || 1 -0.89 -0.43 -0.68 -0.93 -0.16 0.49 -0.15 0.22 -0.38 -0.14 -0.12 -0.54 -0.47 -0.16 0.10 0.34
11239 || orf19.1724 || || || Protein of unknown function; induced by nitric oxide independent of Yhb1p || 1 -1.14 0.29 -0.58 -1.68 0.79 0.06 -0.19 0.33 -0.23 -0.38 -0.33 0.02 -0.85 -0.29 0.35 0.77
11240 || orf19.3671 || || || Dubious open reading frame || 1 0.11 0.16 -0.89 -0.46 0.69 0.46 -0.15 0.00 -0.03 -0.46 0.03 -0.11 -0.48 -0.21 0.14 0.70
11241 || orf19.3404 || || || Protein of unknown function; transcription repressed by fluphenazine treatment || 1 0.06 0.23 -1.73 -0.88 1.37 -0.99 0.39 -0.42 -0.53 0.16 -0.19 -0.55 0.29
11242 || orf19.5334 || || || Ortholog od S. cerevisiae Tis11, a mRNA-binding protein; transcription regulated by yeast-hyphal switch; flow model biofilm induced; Spider biofilm repressed || 1 -0.08 -0.00 -0.24 -0.84 0.80 0.79 -0.72 0.20 -0.14 -0.67 -0.05 -0.19 -0.46 -0.24 -0.37 0.21
11243 || orf19.5334 || || || Ortholog od S. cerevisiae Tis11, a mRNA-binding protein; transcription regulated by yeast-hyphal switch; flow model biofilm induced; Spider biofilm repressed || 1 -0.37 -0.35 -0.44 -1.26 0.63 0.70 -0.86 0.13 -0.40 -0.76 -0.26 -0.41 -0.53 -0.35 -0.78 0.36
11244 || orf19.7405 || || || Ortholog of Rad33; involved in nucleotide excision repair in S. cerevisiae; induced by Mnl1 under weak acid stress || 1 0.00 -0.01 0.19 -0.88 0.30 0.34 -0.28 -0.03 0.07 -0.86 -0.10 -0.04 -0.02 -0.10 -0.67 0.77
11245 || orf19.6739 || || || Ortholog(s) have phosphopentomutase activity, role in deoxyribose phosphate catabolic process and cytosol, nucleus localization || 1 -0.03 0.10 -0.17 -0.81 0.45 0.44 0.16 -0.23 0.03 -0.57 -0.02 -0.01 -0.21 -0.31 -0.12 0.27
11246 || orf19.90 || || || Ortholog(s) have cytoplasm localization || 1 -0.46 -0.25 -0.85 -1.09 1.04 0.53 -0.15 -0.51 -0.06 -0.51 0.45 0.18 -0.01 -0.88 0.16 0.69
11247 || orf19.1722 || || || Ortholog of Candida albicans WO-1 : CAWG_02462 || 1 -0.26 0.02 -0.81 -0.82 0.47 0.30 -0.76 -0.57 -0.25 -0.57 0.07 -0.62 0.15 -1.18 -0.40 0.40
11248 || orf19.1906 || || || Protein of unknown function; flow model biofilm induced || 1 -0.38 -0.10 -0.01 -3.32 -0.09 -0.93 -0.58 -0.86 -1.10 1.74 1.38 -0.32 -1.55 -0.00 1.66
11249 || orf19.5479 || FGR12 || || Protein lacking an ortholog in S. cerevisiae; transposon mutation affects filamentous growth; flow model biofilm induced || 1 -0.20 0.12 -0.51 -2.96 -0.34 0.05 -0.44 -0.86 -0.51 -0.17 0.72 -0.90 -0.25 -0.47 0.19
11250 || orf19.1181 || || || Has domain(s) with predicted catalytic activity and membrane localization || 1 0.25 0.15 -0.72 -2.30 0.20 0.00 -0.27 0.21 -0.54 0.34 0.10 0.21 -0.88 -0.58 -0.05 0.40
11251 || orf19.6595 || RTA4 || || Protein similar to S. cerevisiae Rsb1p, involved in fatty acid transport; transposon mutation affects filamentous growth; alkaline downregulated; caspofungin induced; possibly an essential gene; Hap43p-repressed || 1 0.80 0.64 -0.85 -2.40 0.40 -0.27 -0.44 0.23 -0.46 -0.26 0.99 0.92 -0.03 -0.30 0.77 1.20
11252 || orf19.1434 || || || Ortholog(s) have protein kinase activator activity || 1 0.18 0.37 -0.77 -1.20 0.36 0.15 0.14 0.43 -0.02 0.26 0.55 0.19 0.12 -0.21 -0.06 0.88
11253 || orf19.4170 || CSP2 || || Putative cell wall associated protein; C. albicans and C. dubliniensis specific gene highly induced during chlamydospore development in both species; localized to chlamydospore cell wall; Hap43-repressed; Spider biofilm induced || 1 0.14 0.70 -1.55 -2.54 0.28 0.99 0.57 -0.48 -0.67 -0.60 0.56 -0.46 -0.56 -0.22 -0.48 1.92
11254 || orf19.6595 || RTA4 || || Protein similar to S. cerevisiae Rsb1p, involved in fatty acid transport; transposon mutation affects filamentous growth; alkaline downregulated; caspofungin induced; possibly an essential gene; Hap43p-repressed || 1 0.24 0.29 -0.86 -1.10 -0.03 0.63 -0.28 -0.27 -0.28 0.71 0.29 -0.68 -0.12 0.27 1.21
11255 || orf19.5523 || || || Ortholog of C. dubliniensis CD36 : Cd36_62780, C. parapsilosis CDC317 : CPAR2_601690, Candida tenuis NRRL Y-1498 : CANTEDRAFT_113271 and Debaryomyces hansenii CBS767 : DEHA2A06644g || 1 -0.11 -0.14 -0.49 -0.37 0.08 -0.17 0.12 0.37 -0.75 -0.90 1.30 -0.34 -0.94 0.02 -0.45 0.40
11256 || orf19.524 || || || Ortholog(s) have role in mitotic sister chromatid segregation and cytosol, nucleus localization || 1 0.08 -0.05 -0.33 -0.48 0.05 -0.53 -0.00 0.02 -0.38 -0.70 0.07 -0.56 -0.60 0.06 -0.19 0.32
11257 || orf19.1940 || || || Ortholog(s) have role in cellular response to cadmium ion, detoxification of cadmium ion, ubiquinone biosynthetic process and mitochondrial inner membrane localization || 1 0.02 -0.01 -0.99 -1.40 0.20 -0.39 0.09 0.12 -0.19 -0.88 0.17 -0.15 -0.64 -0.06 -0.61 0.28
11258 || orf19.5339 || || || Ortholog of S. cerevisiae Spg5; required for proteasome assembly during quiescence; transcript detected on high-resolution tiling arrays; Spider biofilm induced || 1 -0.03 -0.04 -0.68 -0.96 -0.11 -0.36 0.28 0.27 -0.12 -0.62 0.56 -0.29 -0.33 -0.14 -0.12 0.32
11259 || orf19.2283 || DQD1 || || Putative 3-dehydroquinate dehydratase; ketoconazole-repressed; protein abundance downregulated by macrophages; flow model biofilm induced || 1 0.09 0.05 -0.99 -1.12 0.10 -1.05 0.86 0.62 -0.36 -1.45 0.84 -0.79 -0.54 -0.59 -0.40 -0.36
11260 || orf19.5358 || || || Phosphorylated protein of unknown function || 1 -0.43 -0.12 -0.10 -0.35 0.05 0.03 0.08 0.09 0.01 -0.29 0.26 -0.18 0.13 -0.27 -0.18 0.14
11261 || orf19.593 || FGR32 || || Protein similar to S. cerevisiae Swa2p; induced upon adherence to polystyrene; transposon mutation affects filamentous growth; Hap43p-repressed gene || 1 -0.30 -0.53 -0.32 -0.46 0.04 -0.19 0.13 -0.03 -0.14 -0.63 0.38 -0.39 0.10 -0.19 0.32 0.14
11262 || orf19.3053 || || || Protein of unknown function; present in exponential and stationary phase yeast; identified in extracts from biofilm and planktonic cells; flow model biofilm induced gene; GlcNAc-induced protein || 1 -0.35 -0.44 -0.81 -1.22 -0.17 -0.21 0.49 -0.02 -0.10 -1.53 0.32 -0.24 0.12 -0.61 0.15 -0.00
11263 || orf19.4812 || || || Phosphopantetheine:protein transferase (PPTase); Spider biofilm induced || 1 -0.80 -0.61 -0.65 -1.26 0.06 0.56 0.68 0.32 -0.02 -0.43 0.01 -0.32 -0.25 0.13 -0.08 -0.06
11264 || orf19.7325 || SCO1 || || Putative copper transporter; Hap43p-repressed gene || 1 -0.38 -0.33 -0.44 -1.12 0.10 0.46 0.24 0.13 0.89 -0.20 -0.26 -0.20 -0.42 -0.36 -0.37 -0.15
11265 || orf19.7325 || SCO1 || || Putative copper transporter; Hap43p-repressed gene || 1 -0.39 -0.43 -0.98 -1.83 0.21 0.45 0.40 0.27 0.73 -0.40 -0.29 0.01 -0.52 -0.09 -0.09 -0.01
11266 || orf19.6263 || || || Predicted MFS membrane transporter; member of the monocarboxylate porter (MCP) family; Spider biofilm induced || 1 -1.03 -0.68 -0.88 -0.78 -0.35 0.15 0.42 0.21 0.66 -0.74 -0.39 -0.05 -0.52 -0.11 0.06 -0.21
11267 || orf19.2607 || || || Protein of unknown function; Spider biofilm induced || 1 -1.25 -1.18 -0.70 -1.35 -0.05 -0.05 0.98 0.15 1.06 -1.57 -0.10 -0.22 -0.70 -0.31 -0.25 -0.07
11268 || orf19.2607 || || || Protein of unknown function; Spider biofilm induced || 1 -1.20 -0.96 -0.75 -0.75 0.05 0.33 1.27 0.42 1.12 -1.35 0.33 -0.45 -0.66 -0.13 -0.09 0.05
11269 || orf19.2092 || || || Putative peroxisomal cystathionine beta-lyase; Gcn4p-regulated || 1 -0.77 -0.60 -0.59 -0.77 0.27 -0.01 0.28 -0.16 0.71 -0.61 0.19 0.16 -0.24 -0.24 0.15 0.36
11270 || orf19.4984 || || || Has domain(s) with predicted chitin binding, chitinase activity and role in carbohydrate metabolic process, cell wall macromolecule catabolic process, chitin catabolic process || 1 -0.38 -0.27 -0.66 -0.92 0.57 0.32 0.40 0.40 0.46 -0.54 0.35 0.06 -0.03 -0.08 0.02 0.19
11271 || orf19.1290 || XKS1 || || Putative xylulokinase; Hap43-repressed; induced by prostaglandins; rat catheter biofilm repressed || 1 -0.28 -0.34 -0.74 -1.13 0.22 0.33 0.57 0.35 0.06 -1.09 0.50 0.22 -0.72 -0.58 0.43 0.62
11272 || orf19.2989 || GOR1 || || Ortholog(s) have glyoxylate reductase activity, role in glyoxylate catabolic process and cytosol, extracellular region, mitochondrion, nucleus localization || 1 -1.08 -1.03 -1.61 -1.93 0.67 1.25 1.05 0.52 0.98 -2.61 -0.04 0.12 -1.56 -0.78 0.37 0.65
11273 || orf19.2989 || GOR1 || || Ortholog(s) have glyoxylate reductase activity, role in glyoxylate catabolic process and cytosol, extracellular region, mitochondrion, nucleus localization || 1 -0.91 -1.01 -1.96 -2.33 0.88 1.41 1.02 0.54 0.95 -2.90 0.07 0.27 -1.56 -0.80 0.62 0.91
11274 || orf19.1290 || XKS1 || || Putative xylulokinase; Hap43-repressed; induced by prostaglandins; rat catheter biofilm repressed || 1 -0.71 -0.78 -1.07 -1.31 -0.01 0.29 0.21 0.05 0.38 -1.12 0.18 0.16 -0.73 -0.24 0.25 0.43
11275 || orf19.1290 || XKS1 || || Putative xylulokinase; Hap43-repressed; induced by prostaglandins; rat catheter biofilm repressed || 1 -0.61 -0.51 -0.64 -1.12 -0.00 0.64 0.26 0.00 0.43 -1.04 0.23 0.24 -0.51 -0.19 0.10 0.87
11276 || orf19.4777 || DAK2 || || Putative dihydroxyacetone kinase; repressed by yeast-hypha switch; fluconazole-induced; caspofungin repressed; protein enriched in stationary phase yeast cultures; flow model biofilm induced; rat catheter and Spider biofilm repressed || 1 -1.10 -1.10 -1.44 -2.34 1.00 1.01 -0.13 0.01 0.25 -1.43 0.95 0.94 -1.09 -1.14 0.22 0.77
11277 || orf19.1868 || RNR22 || || Putative ribonucleoside diphosphate reductase;colony morphology-related gene regulation by Ssn6; transcript regulated by tyrosol and cell density; Hap43-repressed; Spider biofilm induced || 1 -0.61 -0.57 -0.58 -2.53 0.10 0.91 0.27 -0.25 0.19 -2.16 -0.00 0.14 -0.22 -0.68 -0.17 1.05
11278 || orf19.3781 || || || Protein of unknown function; Hap43-repressed; Spider biofilm induced || 1 -0.30 -0.16 -0.49 -1.28 0.02 0.12 0.01 -0.12 0.12 -0.72 -0.12 0.10 0.22 -0.38 0.13 0.67
11279 || orf19.4828 || || || WD repeat domain protein; Hap43-repressed gene; flow model biofilm induced || 1 -0.63 -0.65 -0.53 -0.95 -0.03 -0.12 0.09 -0.21 0.21 -0.96 -0.52 0.29 -0.22 -0.13 -0.22 0.19
11280 || orf19.2163 || || || Ortholog(s) have cytosol localization || 1 -0.22 -0.28 -0.31 -0.40 -0.22 -0.13 -0.05 -0.20 0.07 -0.40 -0.07 0.09 -0.04 -0.14 0.12 0.05
11281 || orf19.5720 || || || Predicted membrane transporter, member of the monocarboxylate porter (MCP) family, major facilitator superfamily (MFS); ketoconazole or caspofungin repressed; Spider biofilm induced || 1 -0.95 -0.77 -1.22 -0.73 -0.07 0.23 0.06 -0.82 1.15 -1.32 0.04 0.35 -1.25 -1.09 0.24 0.28
11282 || orf19.3273 || || || Ortholog(s) have actin monomer binding, protein kinase inhibitor activity, ribosome binding activity, role in negative regulation of protein phosphorylation and cytoplasm, nucleus, polysome, ribosome localization || 1 -0.43 -0.37 -0.45 -0.67 -0.04 0.19 0.28 -0.12 0.31 -0.65 -0.06 0.27 -0.03 0.33 0.10 0.50
11283 || orf19.7437 || || || Putative protein of unknown function; Hap43p-repressed gene; ortholog of S. cerevisiae YJL218W || 1 -0.90 -0.93 -0.74 -1.20 0.01 0.12 0.59 0.25 0.33 -1.42 -0.03 -0.19 0.55 0.29 0.15 0.79
11284 || orf19.915 || || || Protein of unknown function; Spider biofilm induced || 1 -1.31 -0.95 -1.33 -3.14 0.06 0.67 0.97 0.56 0.23 -1.87 -0.10 -0.05 0.89 0.44 -0.65 0.72
11285 || orf19.915 || || || Protein of unknown function; Spider biofilm induced || 1 -1.20 -0.98 -1.86 -3.44 -0.23 0.48 0.43 0.33 0.04 -2.07 -0.19 -0.56 0.97 0.43 -0.98 0.80
11286 || orf19.3967 || PFK1 || || Phosphofructokinase alpha subinit; activated by fructose 2,6-bisphosphate, AMP, ATP inhibited; activity reduced on hyphal induction; phagocytosis-repressed; fluconazole, flow model biofilm induced; rat catheter and Spider biofilm repressed || 1 -1.03 -0.92 -1.12 -2.64 -0.40 -0.08 0.32 -0.08 0.51 -1.83 0.19 0.33 0.77 -0.08 -0.94 0.57
11287 || orf19.3967 || PFK1 || || Phosphofructokinase alpha subinit; activated by fructose 2,6-bisphosphate, AMP, ATP inhibited; activity reduced on hyphal induction; phagocytosis-repressed; fluconazole, flow model biofilm induced; rat catheter and Spider biofilm repressed || 1 -1.13 -1.01 -1.00 -2.45 -0.39 0.01 0.54 0.06 0.60 -1.78 0.28 0.57 0.87 0.02 -0.71 0.96
11288 || orf19.7638 || PRO1 || || Putative gamma-glutamyl kinase; transcript regulated by Nrg1; regulated by Gcn2 and Gcn4; Hap43-repressed gene; early-stage flow model biofilm induced gene || 1 -0.50 -0.54 -1.20 -1.38 -0.16 -0.20 0.65 0.13 0.26 -0.73 0.29 -0.01 0.10 0.10 -0.14 0.66
11289 || orf19.1034 || || || Protein with a predicted cytochrome b5-like Heme/Steroid binding domain; Hap43, caspofungin repressed; flow model biofilm induced || 1 -0.64 -0.64 -1.33 -1.96 -0.42 -0.33 0.75 0.39 0.13 -1.64 1.03 0.22 0.56 0.05 -1.12 0.79
11290 || orf19.6540 || PFK2 || || Phosphofructokinase beta subunit; fructose 2,6-bisphosphate, AMP activated; ATP inhibited; phagocytosis, hyphal repressed; fluconazole-induced; stationary-phase enriched; flow model biofilm induced; rat catheter/Spider biofilm repressed || 1 -0.67 -0.47 -1.39 -2.54 -0.28 -0.38 0.77 0.22 0.06 -1.75 0.80 0.10 0.61 -0.10 -0.30 0.85
11291 || orf19.6540 || PFK2 || || Phosphofructokinase beta subunit; fructose 2,6-bisphosphate, AMP activated; ATP inhibited; phagocytosis, hyphal repressed; fluconazole-induced; stationary-phase enriched; flow model biofilm induced; rat catheter/Spider biofilm repressed || 1 -0.38 -0.19 -1.39 -2.63 0.11 -0.29 1.01 0.71 0.26 -1.63 1.32 0.35 0.88 0.13 -0.07 1.05
11292 || orf19.5228 || RIB3 || || 3,4-Dihydroxy-2-butanone 4-phosphate synthase; homodimeric enzyme of riboflavin biosynthesis; converts ribulose 5-phosphate to L-3,4-dihydroxy-2-butanone 4-phosphate; transcription regulated on yeast-hyphal switch, macrophage interaction || 1 -0.34 -0.50 -1.98 -2.76 0.84 0.04 0.62 0.48 -0.18 -1.71 1.05 0.26 0.83 -0.46 0.11 0.43
11293 || orf19.1289 || SCT1 || || Putative glycerol-3-phosphate O-acyltransferase; fungal-specific (no human or murine homolog) || 1 -0.17 -0.30 -0.62 -0.74 0.30 0.10 0.17 0.06 0.17 -0.52 0.11 0.02 0.12 -0.23 -0.25 0.11
11294 || orf19.7404 || || || Catabolic L-serine (L-threonine) deaminase;, catalyzes degradation of L-serine and L-threonine; required to use serine or threonine as a sole nitrogen source; Spider biofilm repressed || 1 -0.07 -0.25 -0.72 -0.97 -0.43 -0.01 0.46 0.19 0.31 -0.71 0.26 0.12 0.09 0.18 -0.77 0.40
11295 || orf19.6559 || || || RNA polymerase III transcription initiation factor complex (TFIIIC) subunit; growth phase regulated protein; downregulaated in stationary phase yeast cultures; Hap43-repressed; flow model biofilm induced; Spider biofilm repressed || 1 -0.60 -0.54 -0.81 -1.60 -0.25 -0.19 0.89 0.65 0.53 -0.97 0.83 -0.02 0.82 0.92 -0.61 1.29
11296 || orf19.6977 || GPI1 || || Putative protein of GPI synthesis; expression is reduced in a fluconazole-resistant isolate || 1 -0.40 -0.32 -1.46 -2.39 -0.59 -0.33 -0.21 0.17 0.43 -0.43 -0.40 0.22 0.62 1.03 -1.04 0.07
11297 || orf19.4631 || ERG251 || || C-4 sterol methyl oxidase; role in ergosterol biosynthesis; Hap43-induced; ketoconazole-induced; amphotericin B, caspofungin repressed; possibly essential gene, disruptants not obtained by UAU1 method; Spider biofilm repressed || 1 -0.17 -0.16 -0.52 -1.49 -0.32 -0.15 -0.22 -0.26 0.20 -0.77 -0.11 0.07 -0.03 0.28 -0.27
11298 || orf19.4631 || ERG251 || || C-4 sterol methyl oxidase; role in ergosterol biosynthesis; Hap43-induced; ketoconazole-induced; amphotericin B, caspofungin repressed; possibly essential gene, disruptants not obtained by UAU1 method; Spider biofilm repressed || 1 -0.24 -0.35 -0.73 -2.24 -0.65 -0.42 -0.08 -0.07 0.12 -0.87 -0.08 0.03 -0.32 0.20 -0.72 0.81
11299 || orf19.4631 || ERG251 || || C-4 sterol methyl oxidase; role in ergosterol biosynthesis; Hap43-induced; ketoconazole-induced; amphotericin B, caspofungin repressed; possibly essential gene, disruptants not obtained by UAU1 method; Spider biofilm repressed || 1 -0.25 -0.40 -0.79 -3.21 -0.51 -0.38 0.15 0.08 0.32 -0.81 0.05 -0.03 -0.05 0.36 -1.11 0.74
11300 || orf19.4631 || ERG251 || || C-4 sterol methyl oxidase; role in ergosterol biosynthesis; Hap43-induced; ketoconazole-induced; amphotericin B, caspofungin repressed; possibly essential gene, disruptants not obtained by UAU1 method; Spider biofilm repressed || 1 -0.34 -0.34 -0.81 -2.76 -0.57 -0.43 -0.02 -0.05 0.26 -0.90 0.12 -0.05 -0.17 0.16 -0.99 0.62
11301 || orf19.4631 || ERG251 || || C-4 sterol methyl oxidase; role in ergosterol biosynthesis; Hap43-induced; ketoconazole-induced; amphotericin B, caspofungin repressed; possibly essential gene, disruptants not obtained by UAU1 method; Spider biofilm repressed || 1 -0.23 -0.48 -0.81 -2.74 -0.62 -0.56 0.01 0.05 0.31 -0.69 -0.05 -0.16 -0.23 0.21 -0.96 0.31
11302 || orf19.7459 || || || Putative mitochondrial protein with a predicted role in respiratory growth; fluconazole-induced; ketoconazole-repressed; mutants display a strong defect in flow model biofilm formation; Spider biofilm induced || 1 -0.06 -0.09 -1.39 -2.19 0.08 -0.16 0.16 -0.03 -0.25 -0.89 0.02 -0.35 0.57 0.12 -0.96 0.69
11303 || orf19.7459 || || || Putative mitochondrial protein with a predicted role in respiratory growth; fluconazole-induced; ketoconazole-repressed; mutants display a strong defect in flow model biofilm formation; Spider biofilm induced || 1 -0.32 -0.32 -1.58 -2.27 -0.27 -0.26 0.09 -0.26 -0.46 -0.83 -0.22 -0.63 0.37 -0.29 -1.49 0.47
11304 || orf19.7499 || || || Putative nicotinic acid mononucleotide adenylyltransferase, involved in NAD salvage pathway; Spider biofilm repressed || 1 -0.20 -0.14 -1.16 -1.50 -0.45 -0.25 -0.34 -0.16 -0.52 -0.81 0.12 -0.25 0.08 0.02 -0.39 0.41
11305 || orf19.7499 || || || Putative nicotinic acid mononucleotide adenylyltransferase, involved in NAD salvage pathway; Spider biofilm repressed || 1 -0.07 -0.06 -1.12 -1.20 -0.45 -0.18 -0.46 -0.23 -0.45 -0.80 0.11 -0.27 -0.01 -0.10 -0.48 0.24
11306 || orf19.5437 || RHR2 || || Glycerol 3-phosphatase; roles in osmotic tolerance, glycerol accumulation in response to salt; Spider/flow model biofilm induced; regulated by macrophage, stress, yeast-hyphal switch, pheromone, Gcn4, Hog1, Nrg1, Tup1 || 1 -0.13 -0.64 -1.65 -2.10 -0.62 0.37 0.49 -0.01 0.23 -2.00 0.92 0.04 -0.40 -1.41 -2.47 0.50
11307 || orf19.5437 || RHR2 || || Glycerol 3-phosphatase; roles in osmotic tolerance, glycerol accumulation in response to salt; Spider/flow model biofilm induced; regulated by macrophage, stress, yeast-hyphal switch, pheromone, Gcn4, Hog1, Nrg1, Tup1 || 1 -0.39 -0.57 -1.16 -2.30 -0.59 0.53 0.30 -0.03 0.10 -1.85 1.11 0.38 -0.32 -1.09 -2.80 0.84
11308 || orf19.5437 || RHR2 || || Glycerol 3-phosphatase; roles in osmotic tolerance, glycerol accumulation in response to salt; Spider/flow model biofilm induced; regulated by macrophage, stress, yeast-hyphal switch, pheromone, Gcn4, Hog1, Nrg1, Tup1 || 1 -0.38 -0.66 -1.16 -2.32 -0.63 0.59 0.18 -0.22 0.37 -1.74 0.90 0.74 -0.42 -0.97 -2.67
11309 || orf19.5437 || RHR2 || || Glycerol 3-phosphatase; roles in osmotic tolerance, glycerol accumulation in response to salt; Spider/flow model biofilm induced; regulated by macrophage, stress, yeast-hyphal switch, pheromone, Gcn4, Hog1, Nrg1, Tup1 || 1 -0.48 -0.64 -1.27 -2.33 -0.59 0.38 0.07 -0.35 0.24 -1.79 0.78 0.28 -0.38 -0.92 -2.64 0.76
11310 || orf19.5437 || RHR2 || || Glycerol 3-phosphatase; roles in osmotic tolerance, glycerol accumulation in response to salt; Spider/flow model biofilm induced; regulated by macrophage, stress, yeast-hyphal switch, pheromone, Gcn4, Hog1, Nrg1, Tup1 || 1 -0.51 -0.71 -1.45 -2.38 -0.77 0.41 0.13 -0.38 -0.17 -2.07 0.79 0.32 -0.50 -1.16 -2.78 0.86
11311 || orf19.4048 || DES1 || || Putative delta-4 sphingolipid desaturase; planktonic growth-induced gene || 1 -0.21 -0.21 -0.50 -1.15 -1.02 -0.51 -0.15 -0.28 -0.09 -0.77 -0.10 -0.04 -0.38 -0.19 -1.31 0.44
11312 || orf19.2803 || HEM13 || || Coproporphyrinogen III oxidase; antigenic; on yeast cell surface, not hyphae; iron-regulated expression; Hap43, macrophage-repressed; farnesol-induced; possibly essential; flow model biofilm induced; rat catheter, Spider biofilm repressed || 1 -0.58 -0.33 -0.89 -2.99 -1.09 -1.06 0.12 -0.30 0.39 -1.28 0.01 0.39 -0.47 -1.00 -1.50 0.67
11313 || orf19.2803 || HEM13 || || Coproporphyrinogen III oxidase; antigenic; on yeast cell surface, not hyphae; iron-regulated expression; Hap43, macrophage-repressed; farnesol-induced; possibly essential; flow model biofilm induced; rat catheter, Spider biofilm repressed || 1 -0.65 -0.44 -0.95 -2.75 -1.34 -1.10 -0.01 -0.45 0.27 -1.85 -0.14 0.15 -0.71 -1.00 -1.44 0.49
11314 || orf19.2803 || HEM13 || || Coproporphyrinogen III oxidase; antigenic; on yeast cell surface, not hyphae; iron-regulated expression; Hap43, macrophage-repressed; farnesol-induced; possibly essential; flow model biofilm induced; rat catheter, Spider biofilm repressed || 1 -0.21 -0.32 -0.58 -2.41 -0.93 -0.85 0.15 -0.06 0.47 -1.77 0.19 0.27 -0.31 -1.14 -1.28 0.42
11315 || orf19.2803 || HEM13 || || Coproporphyrinogen III oxidase; antigenic; on yeast cell surface, not hyphae; iron-regulated expression; Hap43, macrophage-repressed; farnesol-induced; possibly essential; flow model biofilm induced; rat catheter, Spider biofilm repressed || 1 -0.06 -0.12 -0.26 -2.28 -0.82 -0.72 0.31 0.17 0.54 -1.56 0.20 0.42 -0.33 -0.92 -1.15 0.85
11316 || orf19.2803 || HEM13 || || Coproporphyrinogen III oxidase; antigenic; on yeast cell surface, not hyphae; iron-regulated expression; Hap43, macrophage-repressed; farnesol-induced; possibly essential; flow model biofilm induced; rat catheter, Spider biofilm repressed || 1 -0.02 0.12 -0.24 -2.16 -0.87 -0.51 0.46 0.02 -1.74 0.33 0.71 -0.12 -1.03 -0.97 0.76
11317 || orf19.2670 || || || Ortholog(s) have 3-hydroxyacyl-[acyl-carrier-protein] dehydratase activity, role in fatty acid biosynthetic process and mitochondrion localization || 1 -0.19 0.10 -0.25 -0.58 -0.16 0.07 -0.09 -0.08 -0.11 -0.65 0.50 -0.08 -0.38 0.07 -0.16 0.95
11318 || orf19.1314 || || || Protein of unknown function; planktonic growth-induced gene || 1 -0.01 0.11 -0.55 -1.34 -0.25 0.15 0.13 0.26 0.14 -1.18 0.83 0.35 0.29 0.10 -0.08 1.18
11319 || orf19.7007 || || || Ortholog of C. dubliniensis CD36 : Cd36_70990 and Candida albicans WO-1 : CAWG_05464 || 1 -0.17 0.05 -0.21 -0.01 0.40 0.22 0.08 0.69 -1.14 0.59 0.50 0.15 0.75 -0.19 1.98
11320 || orf19.6194 || || || Ortholog of C. dubliniensis CD36 : Cd36_06640, C. parapsilosis CDC317 : CPAR2_208220, Candida tenuis NRRL Y-1498 : CANTEDRAFT_136902 and Debaryomyces hansenii CBS767 : DEHA2F26730g || 1 -0.41 -0.44 -0.48 -0.63 0.01 0.11 0.37 0.47 -0.08 -0.50 0.87 0.36 0.25 0.14 -0.32 0.97
11321 || orf19.7638 || PRO1 || || Putative gamma-glutamyl kinase; transcript regulated by Nrg1; regulated by Gcn2 and Gcn4; Hap43-repressed gene; early-stage flow model biofilm induced gene || 1 -0.33 -0.49 -0.40 -0.81 -0.11 0.14 0.70 0.34 0.40 -0.85 0.34 0.49 -0.04 -0.23 -0.05 0.71
11322 || orf19.3053 || || || Protein of unknown function; present in exponential and stationary phase yeast; identified in extracts from biofilm and planktonic cells; flow model biofilm induced gene; GlcNAc-induced protein || 1 -0.13 -0.20 -0.41 -0.87 0.22 0.42 0.77 0.43 0.19 -1.00 0.77 0.49 0.36 -0.33 0.27 0.64
11323 || orf19.5701 || || || Ortholog(s) have role in DNA replication initiation, establishment of mitotic sister chromatid cohesion and condensed nuclear chromosome kinetochore localization || 1 -0.18 -0.41 -0.90 -1.38 0.27 -0.46 -0.03 0.07 0.04 -0.25 0.35 0.22 -0.16 0.83 0.07 0.79
11324 || orf19.816 || DCK2 || || Protein similar to S. cerevisiae Ylr422wp; transposon mutation affects filamentous growth; induced by Mnl1p under weak acid stress || 1 -0.03 -0.23 -0.83 -0.61 0.01 -0.31 -0.22 0.04 0.09 -0.45 -0.23 -0.03 -0.17 0.31 0.18 0.66
11325 || orf19.669 || PRM1 || || Putative membrane protein with a predicted role in membrane fusion during mating; Hap43p-repressed gene; protein induced during the mating process || 1 -0.05 -0.33 -0.67 -1.08 0.07 -0.03 0.01 0.01 -0.12 -0.57 -0.23 -0.08 0.35 0.75 0.41 1.18
11326 || orf19.4404 || PGA49 || || Putative GPI-anchored protein || 1 0.65 -0.56 -1.29 -1.34 -0.34 0.21 -0.06 -0.55 -0.28 0.97 0.59 0.86 -0.23 1.19
11327 || orf19.4304 || GAP1 || || Amino acid permease; antigenic in human/mouse; 10-12 transmembrane regions; regulated by nitrogen source; alkaline, GlcNAc, phagocytosis induced; WT virulence in mice; Spider and flow model biofilm induced || 1 0.12 -0.12 -1.16 -0.92 -0.09 -0.27 0.12 -0.13 0.50 -0.70 0.10 0.20 -0.03 0.62 -0.32 0.15
11328 || orf19.7637 || YHB4 || || Protein related to flavohemoglobins; not required for wild-type nitric oxide resistance; has predicted globin, FAD-binding, and NAD(P)-binding domains but lacks some conserved residues of flavohemoglobins; Hap43p-repressed gene || 1 -0.47 -0.23 -0.22 -0.60 0.04 0.06 0.47 0.08 1.20 -0.67 -0.44 -0.10 0.29 0.46 -0.71 0.09
11329 || orf19.7637 || YHB4 || || Protein related to flavohemoglobins; not required for wild-type nitric oxide resistance; has predicted globin, FAD-binding, and NAD(P)-binding domains but lacks some conserved residues of flavohemoglobins; Hap43p-repressed gene || 1 -0.28 -0.32 -0.47 -0.64 0.05 0.09 1.05 0.38 1.24 -0.84 -0.29 -0.29 0.44 0.41 -0.85 0.48
11330 || orf19.6103 || || || Ortholog(s) have role in ascospore wall assembly and cytosol localization || 1 -0.16 -0.16 -0.22 -0.23 0.00 0.18 0.28 0.35 0.26 -0.46 0.31 -0.14 0.15 0.01 -0.61 0.47
11331 || orf19.986 || GLY1 || || L-threonine aldolase; complements glycine auxotrophy of S. cerevisiae shm1 shm2 gly1-1 triple mutant; macrophage/pseudohyphal-induced; the GLY1 locus has an RFLP and is triploid in strain SGY269; flow model biofilm induced || 1 -0.47 -0.29 -1.02 -0.75 -0.11 0.12 1.10 0.82 0.51 -0.51 0.67 -0.30 -0.20 1.06 -1.93 0.46
11332 || orf19.986 || GLY1 || || L-threonine aldolase; complements glycine auxotrophy of S. cerevisiae shm1 shm2 gly1-1 triple mutant; macrophage/pseudohyphal-induced; the GLY1 locus has an RFLP and is triploid in strain SGY269; flow model biofilm induced || 1 -0.79 -0.74 -1.28 -1.34 -0.35 -0.06 0.90 0.58 0.20 -0.56 0.54 -0.38 -0.61 1.26 -2.09 0.09
11333 || orf19.6744 || || || Ortholog(s) have role in regulation of mitotic metaphase/anaphase transition and cytosol, nucleus localization || 1 -0.60 -0.51 -0.46 -0.62 0.47 0.01 0.71 0.03 0.11 -0.28 0.18 0.33 -0.22 -0.03 -0.74 0.38
11334 || orf19.5404 || || || Putative cell wall mannoprotein; repressed during the mating process; merged with orf19.5401 into orf19.5404.1; Spider biofilm induced || 1 -0.20 -0.63 -1.11 -0.64 0.13 0.28 0.49 0.19 0.30 -0.65 -0.09 -0.61 0.18 -0.18 -0.32 -0.12
11335 || orf19.1327 || RBT1 || || Cell wall protein with similarity to Hwp1; required for virulence; predicted glycosylation; fluconazole, Tup1 repressed; farnesol, alpha factor, serum, hyphal and alkaline induced; Rfg1, Rim101-regulated || 1 -0.28 -0.43 -0.43 -0.64 0.04 -0.17 0.42 0.16 0.31 -0.42 -0.21 -0.64 0.43 -0.20 0.19 -0.03
11336 || orf19.1649 || RNA1 || || Putative GTPase-activating protein; protein level decreases in stationary phase cultures; Spider biofilm repressed || 1 -0.31 0.17 -0.41 -0.22 -0.27 -0.14 0.01 0.05 0.26 0.11 0.19 -0.05 0.04 0.20 -0.34 -0.24
11337 || orf19.7617 || || || Ortholog(s) have peptide alpha-N-acetyltransferase activity, role in N-terminal protein amino acid acetylation, histone acetylation and NatA complex, cytosol, cytosolic ribosome, nucleus localization || 1 -0.27 0.05 -0.44 -0.42 0.17 -0.42 0.01 0.17 0.33 0.62 0.23 0.28 0.36 0.06 -0.04 -0.51
11338 || orf19.1825 || || || Protein of unknown function; mutants are viable; filament induced; regulated by Nrg1, Rfg1, Tup1 || 1 -0.24 -0.27 -0.65 -0.86 -0.10 -1.70 0.74 0.54 0.52 1.59 0.47 0.15 0.72 -0.00 -1.06 -0.72
11339 || orf19.2657 || || || Protein of unknown function || 1 -0.15 -0.02 -0.95 -0.89 -0.29 0.56 0.99 0.89 1.16 0.49 0.28 0.71 0.81 -0.98 -1.53
11340 || orf19.2443 || RGD1 || || GTPase activator protein; transcript induced in low iron; alkaline upregulated; localized to the bud emergence area in G1 phase and in the bud tip during S and G2 phases || 1 0.23 0.13 -0.44 -0.35 -0.13 -0.65 0.06 0.25 0.65 0.27 0.18 -0.25 0.21 0.13 -0.46 -0.52
11341 || orf19.2387 || || || Putative tRNA-Pro synthetase; genes encoding ribosomal subunits, translation factors, and tRNA synthetases are downregulated upon phagocytosis by murine macrophage || 1 -0.24 -0.16 -0.74 -0.84 -0.31 -0.74 -0.02 0.38 0.40 0.72 -0.31 -0.17 0.03 0.16 -0.25 -0.84
11342 || orf19.6282 || || || Has domain(s) with predicted nucleic acid binding, nucleotide binding activity || 1 -0.33 -0.35 -0.29 -0.52 -0.32 -0.75 0.47 0.63 1.08 0.44 -0.38 -0.45 -0.11 0.35 -0.21 -0.68
11343 || orf19.6156 || || || Ortholog of S. cerevisiae : AIM11, C. glabrata CBS138 : CAGL0I04928g, C. dubliniensis CD36 : Cd36_80770, C. parapsilosis CDC317 : CPAR2_102260 and Candida tenuis NRRL Y-1498 : CANTEDRAFT_114262 || 1 -0.14 -0.34 -0.03 -0.35 -0.29 -1.11 0.58 0.83 0.60 0.67 0.21 -0.55 0.15 -0.20 -0.28 -0.77
11344 || orf19.752 || || || Has domain(s) with predicted methyltransferase activity and role in metabolic process || 1 0.05 0.03 -0.50 -0.70 -0.66 -0.84 0.24 0.72 0.35 -0.01 0.44 -0.26 -0.51 -0.28 -0.37 -0.09
11345 || orf19.5662 || PEP7 || || Vesicle transport protein; acts in endosomal transport; roles in metal ion resistance, virulence, adhesion, hyphal growth, chlamydospore formation; similar to S. cerevisiae Pep7p || 1 -0.10 -0.05 -0.52 -0.34 -0.97 -0.45 0.25 0.31 0.57 0.18 -0.19 -0.39 0.18 0.31 -0.05 -0.06
11346 || orf19.5097 || CAT8 || || Zn(II)2Cys6 transcription factor; similar to S. cerevisiae Cat8 but mutant phenotype suggests different target genes; mutant displays increased filamentous/invasive growth; flucytosine repressed; rat catheter biofilm induced || 1 0.11 0.34 -0.34 -0.40 -1.07 -1.09 0.83 0.47 1.12 -0.08 -0.28 -0.01 -0.32 -0.05 0.05 -0.06
11347 || orf19.7448 || LYS9 || || Saccharopine dehydrogenase; lysine biosynthesis; soluble protein in hyphae; amphotericin B repressed; Gcn4-regulated; colony morphology-related gene regulation by Ssn6; protein present in exponential and stationary growth phase yeast || 1 -0.35 -0.39 -0.28 0.05 -0.56 -0.57 1.07 0.48 1.06 -0.07 -0.25 -0.02 -0.18 0.39 -0.25 -0.20
11348 || orf19.7448 || LYS9 || || Saccharopine dehydrogenase; lysine biosynthesis; soluble protein in hyphae; amphotericin B repressed; Gcn4-regulated; colony morphology-related gene regulation by Ssn6; protein present in exponential and stationary growth phase yeast || 1 -0.19 -0.40 -0.99 0.04 -0.55 -0.50 1.04 0.55 1.05 -0.08 -0.21 -0.01 -0.28 0.32 -0.17 -0.40
11349 || orf19.1394 || || || Putative protein of unknown function; mutant is viable; protein level decreases in stationary phase cultures; Spider biofilm induced || 1 -0.33 -0.31 -0.97 0.03 -0.14 -0.76 0.79 0.88 0.83 0.07 0.39 -0.00 -0.16 0.45 -0.41 -0.01
11350 || orf19.7224 || || || Ortholog(s) have ubiquitin-protein ligase activity and role in histone catabolic process, histone ubiquitination || 1 -0.17 -0.09 -0.29 -0.14 0.06 -0.73 0.07 0.41 0.46 0.20 0.40 0.25 -0.46 0.06 -0.18 0.02
11351 || orf19.3608 || MSH3 || || Mismatch repair protein; predicted role in repair of insertion or deletion mutations and removal of nonhomologous DNA ends; rat catheter biofilm repressed || 1 -0.19 -0.16 -0.88 -0.50 -0.09 -0.60 0.00 0.48 0.55 0.87 0.63 0.56 -0.47 0.14 -0.01 -0.38
11352 || orf19.6563.1 || || || Ortholog(s) have role in mitochondrial respiratory chain complex IV assembly, negative regulation of mitochondrial translation and integral to mitochondrial inner membrane localization || 1 -0.16 -0.13 -0.50 -0.67 0.06 -0.19 0.35 0.64 0.69 0.45 0.05 0.13 -0.47 -0.13 -0.16 -0.09
11353 || orf19.7485 || || || Putative mitochondrial ribosomal protein of the large subunit; Hap43p-repressed gene; ortholog of S. cerevisiae MRPL9 || 1 0.04 -0.14 -0.77 -0.79 -0.05 -0.55 0.29 0.83 0.53 0.64 0.23 -0.12 -0.14 -0.32 0.17 -0.09
11354 || orf19.6632 || ACO2 || || Putative aconitate hydratase 2; induced in high iron; regulated by Gcn4; repressed by amino acid starvation (3-AT); protein levels decrease in stationary phase yeast; flow model and Spider biofilm repressed || 1 -0.41 -0.28 -0.96 -0.49 0.02 -0.66 0.55 0.55 1.07 0.48 0.31 0.64 -0.55 -0.63 0.00 -0.24
11355 || orf19.4506 || LYS22 || || Putative homocitrate synthase; repressed by nitric oxide and by hypoxia; protein level decreases in stationary phase cultures; induced by ketoconazole, Spider biofilm induced; flow model biofilm repressed || 1 -0.26 -0.17 -0.77 -0.38 -0.54 -0.47 0.79 0.32 0.75 0.26 0.11 0.19 -0.62 -0.59 -0.05 -0.28
11356 || orf19.1517 || ARO3 || || 3-deoxy-D-arabinoheptulosonate-7-phosphate synthase; aromatic amino acid synthesis; GCN-regulated; feedback-inhibited by phe if expressed in S. cerevisiae; decreased in stationary phase; flow model biofilm repressed || 1 -0.41 -0.51 -0.71 -0.27 -0.69 -1.23 1.01 0.68 1.50 0.55 0.21 0.35 -1.25 -0.75 -0.32 -0.87
11357 || orf19.3846 || LYS4 || || Homoaconitase; regulated by Gcn4, Gcn2; induced in response to amino acid starvation (3-AT); induced by human whole blood or PMNs; Hap43-repressed; flow model and Spider biofilm repressed || 1 -0.31 -0.27 -0.30 -0.04 -0.52 -0.79 0.35 0.57 1.08 0.46 0.18 0.47 -0.80 -0.37 -0.04 -0.01
11358 || orf19.1517 || ARO3 || || 3-deoxy-D-arabinoheptulosonate-7-phosphate synthase; aromatic amino acid synthesis; GCN-regulated; feedback-inhibited by phe if expressed in S. cerevisiae; decreased in stationary phase; flow model biofilm repressed || 1 -0.02 0.05 -0.18 -0.01 -0.17 -0.76 1.04 0.57 1.35 0.24 0.34 0.30 -0.40 -0.81 -0.24 -0.45
11359 || orf19.1857 || || || Putative L-azetidine-2-carboxylic acid acetyltransferase; mutants are viable || 1 0.60 -0.09 -0.17 0.38 -0.15 -1.02 0.50 0.69 0.94 -0.16 -0.03 -0.02 -0.16 0.13 -0.45 -0.17
11360 || orf19.105 || HAL22 || || Putative phosphoadenosine-5'-phosphate or 3'-phosphoadenosine 5'-phosphosulfate phosphatase; possible role in sulfur recycling; Hap43-repressed; F-12/CO2 biofilm induced || 1 -0.24 -0.13 -0.26 0.31 -0.32 -0.65 0.25 0.58 0.22 0.39 0.07 0.16 -0.51 -0.25 0.05 -0.23
11361 || orf19.3983 || || || Protein with a predicted transcription factor BTF3 domain; flow model biofilm induced || 1 -0.09 0.13 -0.39 0.04 -0.97 -0.68 0.17 0.44 -0.09 0.79 -0.32 0.13 -0.85 -0.77 -0.06 -0.23
11362 || orf19.843 || || || Putative DNA repair exonuclease; fungal-specific (no human or murine homolog) || 1 -0.16 -0.21 -0.08 0.04 -0.21 -0.36 -0.10 0.12 0.21 0.22 -0.31 0.05 -0.35 -0.27 -0.10 -0.00
11363 || orf19.2042 || || || Ortholog(s) have role in mitochondrial tRNA wobble uridine modification and mitochondrial inner membrane localization || 1 -0.16 -0.41 0.10 -0.16 -0.49 -0.72 -0.32 -0.19 -0.02 0.20 -0.26 -0.02 -0.27 -0.31 -0.09 0.23
11364 || orf19.6366 || || || Has domain(s) with predicted RNA binding activity || 1 -0.38 -0.23 -0.22 -0.40 -0.58 -0.81 -0.18 -0.33 -0.46 0.22 -0.28 0.21 -0.80 -0.61 -0.25 0.21
11365 || orf19.1897 || || || Ortholog of C. dubliniensis CD36 : Cd36_21640, C. parapsilosis CDC317 : CPAR2_105040, Candida tenuis NRRL Y-1498 : CANTEDRAFT_112352 and Debaryomyces hansenii CBS767 : DEHA2C08008g || 1 -0.87 -0.26 -0.04 -0.38 -1.64 -1.11 -0.44 -0.39 -0.43 -0.39 -0.41 0.38 -1.04 0.03 -1.14 0.30
11366 || orf19.4468 || || || Putative succinate dehydrogenase; localized to the mitochondrial membrane; Hap43p-repressed gene || 1 0.09 0.03 0.03 0.33 -1.13 -0.92 -0.20 0.28 -0.01 0.28 -0.19 -0.05 -1.28 -1.00 -0.94 -0.72
11367 || orf19.5753 || HGT10 || || Glycerol permease involved in glycerol uptake; member of the major facilitator superfamily; induced by osmotic stress, at low glucose in rich media, during cell wall regeneration; 12 membrane spans; Hap43p-induced gene || 1 -0.73 -0.66 -1.25 -0.32 -3.70 -3.36 -0.52 -0.05 -1.29 0.91 0.73 0.67 -2.98 -2.20 -2.36 -2.32
11368 || orf19.5753 || HGT10 || || Glycerol permease involved in glycerol uptake; member of the major facilitator superfamily; induced by osmotic stress, at low glucose in rich media, during cell wall regeneration; 12 membrane spans; Hap43p-induced gene || 1 -0.83 -0.58 -1.05 -0.07 -2.92 -3.16 -0.44 -0.05 -1.10 0.95 0.62 0.58 -2.71 -2.13 -1.99 -1.89
11369 || orf19.3838 || EFB1 || || Translation elongation factor EF-1 beta; repressed by human whole blood or PMNs; macrophage/pseudohyphal-induced; antigenic in mouse; farnesol-downregulated; snoRNA snR18 is encoded within the EFB1 intron; Spider biofilm repressed || 1 -0.16 -0.24 -0.59 -0.82 0.08 0.06 -0.14 0.21 0.15 -0.28 -0.79 -0.35 -0.76 -0.46
11370 || orf19.3838 || EFB1 || || Translation elongation factor EF-1 beta; repressed by human whole blood or PMNs; macrophage/pseudohyphal-induced; antigenic in mouse; farnesol-downregulated; snoRNA snR18 is encoded within the EFB1 intron; Spider biofilm repressed || 1 -0.25 -0.34 -0.45 0.07 -0.76 -0.92 -0.03 0.05 0.00 0.23 -0.10 -0.61 -0.90 -0.73 -0.95 -0.68
11371 || orf19.5517 || || || Similar to alcohol dehydrogenases; induced by benomyl treatment, nitric oxide; induced in core stress response; oxidative stress-induced via Cap1; Spider biofilm repressed || 1 -0.83 -0.80 -1.01 -0.28 -1.89 -1.19 -0.03 -0.20 -0.72 -0.04 0.49 0.83 -1.95 -0.91 -3.21 -0.87
11372 || orf19.5517 || || || Similar to alcohol dehydrogenases; induced by benomyl treatment, nitric oxide; induced in core stress response; oxidative stress-induced via Cap1; Spider biofilm repressed || 1 -0.98 -1.05 -1.30 -0.68 -1.96 -1.28 -0.02 -0.39 -0.69 0.07 0.49 0.76 -1.91 -0.96 -3.31 -0.85
11373 || orf19.2417 || SMC5 || || Protein similar to S. cerevisiae Smc5p, which is involved in DNA repair; transposon mutation affects filamentous growth || 1 -0.95 -0.64 -0.46 -0.14 -0.55 -0.76 -0.56 -0.05 -0.36 0.77 0.43 0.18 -0.94 -0.24 -1.50 -0.16
11374 || orf19.967 || || || Major mitochondrial nuclease; has RNAse and DNA endo- and exonucleolytic activities; roles in mitochondrial recombination, apoptosis and maintenance of polyploidy; Spider biofilm repressed || 1 -0.43 -0.17 -0.79 -0.59 -0.61 -0.86 0.35 0.59 -0.24 0.30 0.06 -0.04 -1.37 -0.36 -1.20 0.27
11375 || orf19.772 || LYS21 || || Homocitrate synthase; lysine biosynthesis; expression increased in a fluconazole-resistant isolate; colony morphology-related gene regulation by Ssn6; ketoconazole-repressed; regulated by Gcn2, Gcn4, Hap43 || 1 -0.45 -0.52 -0.92 -0.68 -0.62 -0.63 0.08 0.19 -0.06 0.32 0.11 0.23 -1.19 -0.36 -0.75 -0.21
11376 || orf19.772 || LYS21 || || Homocitrate synthase; lysine biosynthesis; expression increased in a fluconazole-resistant isolate; colony morphology-related gene regulation by Ssn6; ketoconazole-repressed; regulated by Gcn2, Gcn4, Hap43 || 1 -0.26 -0.31 -0.82 -1.01 -0.71 -0.87 0.08 0.29 -0.61 -0.14 0.13 -0.08 -1.02 -1.05 -0.80 -0.50
11377 || orf19.637 || SDH2 || || Succinate dehydrogenase, Fe-S subunit; localizes to surface of yeast cells, but not hyphae; induced in high iron and during log phase aerobic growth; repressed by nitric oxide, Hap43 || 1 0.35 0.28 -0.26 -0.35 -0.34 -0.31 0.17 0.17 -0.23 -0.03 -0.08 -0.10 -1.22 -1.49 -0.28 -0.70
11378 || orf19.7563 || BET2 || || Putative Type II geranylgeranyltransferase beta subunit; transcript regulated by Mig1 || 1 0.17 0.28 -0.11 -0.26 -0.49 -0.58 -0.21 -0.11 -0.08 0.00 -0.22 0.00 -0.64 -0.78 -0.16 -0.28
11379 || orf19.6957 || || || Protein of unknown function || 1 -0.09 0.31 -0.61 -0.94 -0.98 -0.47 -0.07 -0.04 -0.42 0.67 0.08 -0.94 -0.22
11380 || orf19.2938 || || || Putative mitochondrial inner membrane protein with a predicted role in the assembly of respiratory complex III; Hap43p-repressed gene; S. cerevisiae ortholog FMP25 localizes to mitochondrion || 1 0.05 0.06 -0.42 -0.61 -0.22 -0.31 -0.07 -0.18 -0.05 0.31 -0.31 0.50 -0.92 -0.95 -0.24 0.01
11381 || orf19.3271 || || || Ortholog of Candida albicans WO-1 : CAWG_01442 || 1 0.28 -0.04 -0.30 -0.91 -0.43 0.03 0.04 0.05 -0.01 -0.06 0.97 -0.85 -0.70 -0.33 -0.12
11382 || orf19.118 || FAD2 || || Delta-12 fatty acid desaturase, involved in production of linoleic acid, which is a major component of membranes || 1 0.20 0.26 -0.45 -0.10 -0.88 -0.87 0.19 0.24 -1.19 0.30 0.02 0.17 -1.55 -1.05 -1.47 0.47
11383 || orf19.118 || FAD2 || || Delta-12 fatty acid desaturase, involved in production of linoleic acid, which is a major component of membranes || 1 0.31 0.25 0.22 0.52 -0.85 -0.56 -0.06 0.08 -0.77 0.54 -0.35 0.08 -1.27 -0.45 -0.79 0.55
11384 || orf19.279 || || || Protein with a predicted D-Tyr-tRNA(Tyr) deacylase domain; Hap43-repressed gene || 1 -0.28 -0.19 -0.33 -0.02 -0.21 -0.03 -0.22 0.20 -0.16 0.07 -0.01 0.09 -0.75 -0.43 -0.21 0.10
11385 || orf19.2956 || MGM101 || || Putative mitochondrial genome maintenance protein; fungal-specific (no human or murine homolog); mutation confers hypersensitivity to tubercidin (7-deazaadenosine) || 1 -0.29 -0.59 -0.02 -0.34 -0.33 -0.16 -0.23 0.03 0.12 0.48 0.06 0.14 -1.01 -0.13 -0.20 -0.02
11386 || orf19.331 || || || Ortholog(s) have S-adenosylmethionine-dependent methyltransferase activity, protein methyltransferase activity and role in peptidyl-glutamine methylation, regulation of translation || 1 -0.27 -0.10 0.04 -0.09 -0.28 -0.29 -0.16 0.22 0.00 0.19 0.20 0.25 -0.31 0.05 -0.04 -0.10
11387 || orf19.3952 || SRP101 || || Signal recognition particle (SRP) receptor alpha subunit; involved in SRP-dependent protein targeting; rat catheter biofilm repressed || 1 -0.31 -0.40 -0.34 -0.34 -0.69 -0.83 -0.14 0.05 0.10 0.44 0.28 0.42 -0.76 0.25 -0.04 -0.48
11388 || orf19.4940 || || || Putative histidine permease; fungal-specific (no human or murine homolog); Hap43p-induced gene || 1 -0.08 -0.11 -0.30 -0.51 -0.50 -0.98 -0.11 0.01 0.20 0.40 0.11 0.33 -0.61 -0.35 0.27 -0.16
11389 || orf19.3915 || || || Putative metallodipeptidase; protein present in exponential and stationary growth phase yeast; Hog1-induced; Hap43-repressed; sumoylation target; Spider biofilm repressed || 1 -0.03 0.08 -0.34 -0.66 -0.07 0.12 0.58 0.20 0.44 -0.00 -0.02 0.34 -0.51 -0.27 -0.39 -0.04
11390 || orf19.125 || EBP1 || || NADPH oxidoreductase; interacts with phenolic substrates (17beta-estradiol); possible role in estrogen response; induced by oxidative, weak acid stress, NO, benomyl, GlcNAc; Cap1, Mnl1 induced; Hap43-repressed; rat catheter biofilm induced || 1 -0.29 -0.28 -0.02 -0.60 -0.77 0.24 0.62 -0.08 0.32 -0.32 0.21 0.65 -1.38 -1.01 -1.52 -0.25
11391 || orf19.125 || EBP1 || || NADPH oxidoreductase; interacts with phenolic substrates (17beta-estradiol); possible role in estrogen response; induced by oxidative, weak acid stress, NO, benomyl, GlcNAc; Cap1, Mnl1 induced; Hap43-repressed; rat catheter biofilm induced || 1 -0.31 -0.32 -0.15 -1.14 -0.52 0.41 0.70 -0.32 0.07 -0.40 0.31 0.73 -1.68 -1.06 -1.61 -0.09
11392 || orf19.125 || EBP1 || || NADPH oxidoreductase; interacts with phenolic substrates (17beta-estradiol); possible role in estrogen response; induced by oxidative, weak acid stress, NO, benomyl, GlcNAc; Cap1, Mnl1 induced; Hap43-repressed; rat catheter biofilm induced || 1 -0.51 -0.50 -0.57 -1.70 -0.89 0.51 0.43 -0.44 0.47 -0.28 0.16 0.98 -2.66 -1.40 -2.28 0.23
11393 || orf19.125 || EBP1 || || NADPH oxidoreductase; interacts with phenolic substrates (17beta-estradiol); possible role in estrogen response; induced by oxidative, weak acid stress, NO, benomyl, GlcNAc; Cap1, Mnl1 induced; Hap43-repressed; rat catheter biofilm induced || 1 -0.60 -0.69 -0.95 -1.87 -0.94 0.11 0.47 -0.29 0.04 -0.40 0.16 0.63 -2.21 -1.25 -1.95 -0.65
11394 || orf19.3433 || OYE23 || || Putative NAPDH dehydrogenase; induced by nitric oxide, benomyl; oxidative stress-induced via Cap1; Hap43p-repressed; rat catheter biofilm induced || 1 -0.37 -0.51 -0.91 -1.46 -1.06 0.15 0.26 -0.53 0.15 -0.16 0.09 0.73 -2.53 -1.49 -1.41 0.17
11395 || orf19.3175 || || || Putative ortholog of human electron transfer flavoprotein dehydrogenase (ETF-dH); alkaline repressed; repressed by nitric oxide; virulence-group-correlated expression; Spider biofilm induced || 1 -0.64 -0.79 -1.19 -1.59 -0.60 -0.37 0.75 0.09 0.38 -0.80 0.42 0.55 -1.58 -1.01 -0.63 0.46
11396 || orf19.3175 || || || Putative ortholog of human electron transfer flavoprotein dehydrogenase (ETF-dH); alkaline repressed; repressed by nitric oxide; virulence-group-correlated expression; Spider biofilm induced || 1 -0.74 -0.80 -1.35 -1.60 -0.58 -0.28 0.64 0.23 0.56 -0.62 0.50 0.61 -1.46 -0.97 -0.54 0.27
11397 || orf19.6744 || || || Ortholog(s) have role in regulation of mitotic metaphase/anaphase transition and cytosol, nucleus localization || 1 -0.74 -0.68 -0.37 -0.64 0.09 0.01 -0.01 0.05 0.19 0.02 -0.02 0.40 -0.76 -0.62 -0.69 0.33
11398 || orf19.3112 || ZRT1 || || Putative zinc transporter; acts with Pra1 in sequestration of zinc from host tissues during infection; hyphal, macrophage-induced; alkaline induced upon adherence to polystyrene; induced in oralpharyngeal candidasis; Spider biofilm induced || 1 -0.39 -0.69 -0.87 -0.93 -0.60 -0.10 -0.32 -0.58 0.27 -0.05 0.15 0.88 -0.64 -1.63 -0.69 -0.45
11399 || orf19.597 || || || Protein with an aspartate aminotransferase domain; Gcn4-regulated || 1 -0.31 -0.52 -0.22 -0.05 -0.40 -0.35 0.24 0.13 0.65 -0.95 0.04 0.03 -1.33 -0.61 -0.96 -0.36
11400 || orf19.3905 || MRV5 || || Planktonic growth-induced gene || 1 0.26 -0.19 -0.81 -1.29 -0.62 0.68 -0.98 -1.04 -0.79 -0.88 0.01 0.88 -1.41 -1.68 -1.70 0.30
11401 || orf19.562 || FGR13 || || Protein encoded in retrotransposon Zorro3 with a potential zinc finger; lacks an ortholog in S. cerevisiae; transposon mutation affects filamentous growth || 1 -0.17 -0.38 -0.22 -0.19 -0.49 0.08 -0.02 -0.15 -0.13 0.24 -0.17 -0.03 -0.11 -0.04 -0.51 0.47
11402 || orf19.6569 || || || Predicted transmembrane transporter; induced during chlamydospore formation in both C. albicans and C. dubliniensis || 1 -0.16 -0.96 -1.03 -1.04 -1.86 0.06 -0.14 0.26 0.44 -0.52 -0.66 -0.63 0.09 -1.89 0.46
11403 || orf19.7534 || MIS12 || || Mitochondrial C1-tetrahydrofolate synthase precursor || 1 -0.43 -0.45 -0.35 -0.08 -0.63 -0.31 0.57 0.37 0.54 0.17 -0.22 -0.31 -0.83 -0.03 -1.11 0.24
11404 || orf19.5443 || BNA4 || || Putative kynurenine 3-monooxygenase, involved in NAD biosynthesis; transposon mutation affects filamentous growth; Hap43p-repressed gene; oral infection upregulated; mutants have reduced capacity to damage oral epithelial cells || 1 0.04 -0.01 -0.41 -1.05 -0.67 -0.10 0.42 0.41 0.71 0.31 -0.35 0.25 -0.50 0.03 -0.57 0.56
11405 || orf19.6884 || GWT1 || || Inositol acyltransferase with role in early steps of GPI anchor biosynthetic process; antifungal drug target || 1 -0.44 -0.45 -0.16 -0.11 -0.44 -0.13 0.05 0.11 0.50 0.25 -0.11 0.21 0.12 0.09 0.12 0.15
11406 || orf19.4159 || || || Has domain(s) with predicted role in transmembrane transport || 1 -0.47 -0.77 -0.28 -0.47 -1.11 -0.42 0.06 0.36 0.43 0.84 -0.06 0.10 0.06 0.35 -0.37 0.19
11407 || orf19.6984 || || || Ortholog of C. dubliniensis CD36 : Cd36_85460, C. parapsilosis CDC317 : CPAR2_405760, Candida tenuis NRRL Y-1498 : CANTEDRAFT_116052 and Debaryomyces hansenii CBS767 : DEHA2D16940g || 1 -0.24 -0.36 0.20 0.22 -0.10 -0.28 0.02 0.30 0.01 0.45 -0.72 -0.20 0.08 -0.08 -0.37 -0.45
11408 || orf19.4539 || || || Protein with a Rho GDP-dissociation inhibitor domain; Hap43-repressed gene; Spider biofilm induced || 1 -0.43 -0.51 -0.09 0.26 -0.54 -0.44 -0.26 0.18 0.13 0.21 -0.83 -0.40 0.02 -0.15 -0.31 -0.61
11409 || orf19.4539 || || || Protein with a Rho GDP-dissociation inhibitor domain; Hap43-repressed gene; Spider biofilm induced || 1 -0.80 -0.69 -0.35 0.16 -0.81 -0.74 -0.20 0.32 0.29 0.28 -1.01 -0.14 0.21 0.12 -0.38 -0.92
11410 || orf19.4117 || || || Ortholog of C. dubliniensis CD36 : Cd36_20450, C. parapsilosis CDC317 : CPAR2_104160, Candida tenuis NRRL Y-1498 : CANTEDRAFT_95516 and Debaryomyces hansenii CBS767 : DEHA2F05192g || 1 -0.27 -0.19 -0.45 -0.60 -0.45 -0.70 -0.14 0.15 0.12 -0.06 0.30 0.10 0.04 0.39 -0.16 -0.60
11411 || orf19.1718 || ZCF8 || || Predicted Zn(II)2Cys6 transcription factor; repressed by fluphenazine treatment; required for yeast cell adherence to silicone substrate || 1 -0.49 -0.40 -0.73 -0.23 -0.28 -1.00 0.07 0.08 -0.21 -0.31 -0.23 -0.02 0.27 0.51 -0.04 -0.42
11412 || orf19.5001 || CUP2 || || Putative copper-binding transcription factor; required for normal resistance to copper; activates transcription of metallothionein genes; Hap43-repressed; Spider biofilm induced || 1 0.03 -0.10 -0.62 -0.38 -0.37 -0.45 0.44 -0.58 -0.35 -0.35 -0.59 -0.47 0.61 -0.26 -0.21 -0.70
11413 || orf19.4849 || || || Protein required for localizing proteasomes to the nucleus; involved in ubiquitin-mediated protein degradation; possibly an essential gene, disruptants not obtained by UAU1 method; Spider biofilm induced || 1 0.12 0.03 -0.62 -0.19 -0.46 -0.59 0.69 -0.01 -0.32 0.03 -0.30 -0.48 0.19 0.15 -0.26 -0.79
11414 || orf19.4163 || || || Ortholog(s) have role in protein targeting to vacuole, receptor-mediated endocytosis, response to pheromone and actin cortical patch, cytosol, endosome, plasma membrane, ribosome localization || 1 0.22 0.02 -1.00 -0.57 -0.44 -0.95 0.11 -0.06 -0.60 -0.06 -0.12 -0.58 0.38 -0.29 -0.25 -0.69
11415 || orf19.3865 || RFX1 || || Transcription factor; involved in DNA damage responses, morphogenesis, and virulence; Spider biofilm induced || 1 -0.02 0.08 -0.57 -0.22 -0.14 -0.62 0.25 -0.25 -0.05 -0.05 -0.25 -0.17 0.15 -0.01 -0.12 -0.31
11416 || orf19.1555 || SAC3 || || Putative nuclear pore-associated protein, required for small ribosomal subunit biogenesis; possibly an essential gene, disruptants not obtained by UAU1 method || 1 0.04 0.13 -0.60 -0.44 -0.26 -0.59 0.37 -0.03 -0.02 0.04 -0.39 -0.32 0.42 0.14 -0.51 -0.19
11417 || orf19.2501 || FLC1 || || Protein involved in heme uptake; putative FAD transporter, similar to S. cerevisiae Flc1; regulated by iron; macrophage-induced; mutant defective in filamentous growth; Spider biofilm induced || 1 0.00 -0.08 -0.52 -0.39 -0.19 -0.14 0.16 -0.36 -0.28 0.28 -0.68 -0.65 0.71 0.21 -0.44 -0.25
11418 || orf19.4649 || ZCF27 || || Putative Zn(II)2Cys6 transcription factor || 1 -0.34 -0.21 -1.03 -1.09 -0.31 -0.43 0.02 -0.04 0.19 -0.23 -0.90 -0.77 1.78 0.09 -1.06 -1.48
11419 || orf19.4645 || BEM1 || || Protein required for wild-type budding, hyphal growth, and virulence in a mouse systemic infection; suppresses pseudohyphal and filamentous growth defects of various S. cerevisiae mutants and heat sensitivity of S. cerevisiae cdc24-4 mutant || 1 -0.15 -0.13 -0.82 -1.03 -0.09 -1.05 0.72 0.76 0.57 0.32 0.10 -0.22 1.21 0.63 -0.21 -0.13
11420 || orf19.4645 || BEM1 || || Protein required for wild-type budding, hyphal growth, and virulence in a mouse systemic infection; suppresses pseudohyphal and filamentous growth defects of various S. cerevisiae mutants and heat sensitivity of S. cerevisiae cdc24-4 mutant || 1 -0.27 -0.30 -1.10 -1.15 -0.41 -1.35 0.45 0.70 0.19 0.29 -0.03 -0.40 1.10 0.38 -0.30 -0.13
11421 || orf19.1961 || || || Planktonic growth-induced gene || 1 -0.14 -0.19 -0.83 -1.21 -0.37 -0.89 0.59 0.61 0.52 0.12 0.13 -0.26 0.61 -0.11 -0.25 0.36
11422 || orf19.5033 || || || Ortholog(s) have Atg8 ligase activity, protein tag activity || 1 -0.27 -0.45 -0.71 -0.79 -0.14 -0.66 0.29 0.72 0.42 0.07 -0.07 -0.21 0.27 -0.16 -0.27
11423 || orf19.1961 || || || Planktonic growth-induced gene || 1 -0.50 -0.40 -0.94 -1.30 -1.27 -1.59 0.73 0.49 0.38 0.03 -0.11 -0.79 0.50 -0.42 -1.12 0.06
11424 || orf19.4645 || BEM1 || || Protein required for wild-type budding, hyphal growth, and virulence in a mouse systemic infection; suppresses pseudohyphal and filamentous growth defects of various S. cerevisiae mutants and heat sensitivity of S. cerevisiae cdc24-4 mutant || 1 -0.42 -0.32 -1.13 -1.30 -0.56 -1.60 0.31 0.26 0.09 0.04 -0.30 -1.13 0.92 -0.14 -0.50 -0.35
11425 || orf19.4645 || BEM1 || || Protein required for wild-type budding, hyphal growth, and virulence in a mouse systemic infection; suppresses pseudohyphal and filamentous growth defects of various S. cerevisiae mutants and heat sensitivity of S. cerevisiae cdc24-4 mutant || 1 -0.50 -0.48 -0.80 -1.20 -0.70 -1.78 0.39 0.60 0.26 0.10 -0.39 -1.02 0.83 0.05 -0.65 -0.61
11426 || orf19.1352 || TIM22 || || Mitochondrial inner membrane protein; predicted role in protein import; Hap43-repressed gene; flow model biofilm induced; Spider biofilm repressed || 1 -0.20 -0.08 -0.87 -1.34 -1.06 -1.37 0.41 0.73 0.32 0.50 -0.42 -1.28 0.51 0.56 -0.82 -0.17
11427 || orf19.6813 || || || Protein of unknown function; Hap43-induced gene || 1 -0.20 -0.81 -1.13 -1.73 -1.30 -1.73 0.83 0.62 -0.74 -0.13 0.81 -0.59 1.59 -0.02 -0.96 -0.29
11428 || orf19.3254 || || || Ortholog of C. dubliniensis CD36 : Cd36_26020, Candida tropicalis MYA-3404 : CTRG_00984 and Candida albicans WO-1 : CAWG_01455 || 1 -0.04 -0.24 -1.02 -1.53 -0.51 -1.51 0.12 0.23 -0.30 0.28 0.30 -0.19 0.39 0.54 -0.12 -0.07
11429 || orf19.341 || || || Putative spermidine export pump; fungal-specific (no human or murine homolog) || 1 0.14 0.64 -1.04 -2.57 -0.83 -3.81 0.62 -0.15 1.16 1.17 -0.67 -1.44 0.13 0.75 -1.49 -0.38
11430 || orf19.2068 || || || Ortholog of C. dubliniensis CD36 : Cd36_15550, C. parapsilosis CDC317 : CPAR2_213190, Candida tenuis NRRL Y-1498 : CANTEDRAFT_119026 and Debaryomyces hansenii CBS767 : DEHA2G08514g || 1 -0.08 0.11 -0.49 -0.61 -0.50 -1.26 -0.04 -0.13 0.05 0.37 -0.00 -0.13 -0.27 -0.13 -0.69 -0.32
11431 || orf19.1570 || ERG7 || || 2,3-epoxysqualene-lanosterol cyclase (lanosterol synthase), conversion of 2,3-oxidosqualene to lanosterol in sterol biosynthesis; fluconazole-induced; possibly essential, disruptants not obtained by UAU1 method; rat catheter biofilm induced || 1 -0.27 -0.23 -0.58 -0.65 -0.61 -1.21 0.16 0.26 0.38 0.22 0.05 -0.15 -0.08 -0.04 -0.72 -0.10
11432 || orf19.4718 || TRP5 || || Predicted tryptophan synthase; identified in detergent-resistant membrane fraction (possible lipid raft component); predicted N-terminal acetylation; Gcn4p-regulated; S. cerevisiae ortholog is Gcn4p regulated; upregulated in biofilm; || 1 -0.41 -0.35 -0.76 -1.12 -0.57 -1.41 0.26 -0.18 0.45 -0.29 -0.05 -0.09 -0.23 -0.05 -0.71 0.09
11433 || orf19.2176 || IFM3 || || Protein with a 2-hydroxyacid dehydrogenase catalytic domain; Hap43-repressed; Plc1-regulated; overlaps orf19.2177 || 1 -0.33 -0.55 -0.70 -0.62 -0.32 -0.57 -0.08 0.39 0.34 -0.27 -0.30 -0.60 -0.16 -0.00 0.20 0.14
11434 || orf19.925 || SAM51 || || Component of the SAM complex involved in mitochondrial protein import, involved in beta-barrel protein assembly; member of the Omp85 protein family || 1 -0.40 -0.29 -0.74 -0.62 -0.48 -0.55 0.40 0.58 0.03 -0.18 -0.12 -0.55 -0.01 0.08 -0.01 -0.33
11435 || orf19.1496 || || || Putative transcription factor with zinc finger DNA-binding motif; Hap43p-repressed gene || 1 -0.60 -0.50 -1.26 -0.95 -0.79 -0.65 0.51 0.13 0.16 -0.33 -0.69 -0.48 0.01 -0.08 0.13 -0.56
11436 || orf19.492 || ADE17 || || 5-Aminoimidazole-4-carboxamide ribotide transformylase, enzyme of adenine biosynthesis; antigenic in human; soluble protein in hyphae; not induced during GCN response, in contrast to the S. cerevisiae ortholog || 1 -0.18 -0.20 -0.49 -0.23 -0.50 -0.56 0.13 0.12 0.04 -0.18 -0.17 -0.21 -0.16 -0.19 0.06 -0.40
11437 || orf19.492 || ADE17 || || 5-Aminoimidazole-4-carboxamide ribotide transformylase, enzyme of adenine biosynthesis; antigenic in human; soluble protein in hyphae; not induced during GCN response, in contrast to the S. cerevisiae ortholog || 1 -0.31 -0.33 -0.70 -0.38 -0.57 -0.63 0.05 -0.01 -0.11 -0.51 -0.23 -0.45 -0.29 -0.22 0.19 -0.25
11438 || orf19.3981 || MAL31 || || Putative high-affinity maltose transporter; transcript is upregulated in clinical isolates from HIV+ patients with oral candidiasis; alkaline induced; Spider biofilm induced || 1 -0.92 -0.72 -0.50 -0.92 -1.63 -3.46 0.09 -0.03 -0.24 -0.93 -1.90 -3.26 0.08 1.24 -0.62 -1.02
11439 || orf19.1191 || || || Ortholog(s) have ubiquitin-protein ligase activity and role in ER-associated ubiquitin-dependent protein catabolic process || 1 -0.13 -0.17 -0.03 -0.46 -0.12 -0.55 0.21 0.09 0.27 0.05 -0.37 -0.49 0.15 0.39 -0.19 -0.47
11440 || orf19.6805 || || || Protein of unknown function; Spider biofilm induced || 1 -2.11 -1.72 -2.59 -2.71 -0.84 -2.16 1.78 1.06 1.29 1.02 -1.33 -2.36 2.98 1.18 -0.08 -3.10
11441 || orf19.6805 || || || Protein of unknown function; Spider biofilm induced || 1 -1.49 -1.70 -2.15 -2.24 -0.84 -2.28 1.71 0.70 1.02 0.93 -1.28 -1.92 2.72 1.21 0.02 -2.60
11442 || orf19.6805 || || || Protein of unknown function; Spider biofilm induced || 1 -2.33 -2.46 -2.96 -2.81 -1.33 -2.30 1.63 0.53 1.15 1.47 -2.04 -1.98 2.78 1.39 -0.25 -2.92
11443 || orf19.6805 || || || Protein of unknown function; Spider biofilm induced || 1 -3.19 -3.16 -2.29 -3.00 -2.05 -2.62 0.71 -0.23 0.73 0.63 -2.78 -2.56 1.94 0.91 -0.92 -3.08
11444 || orf19.6805 || || || Protein of unknown function; Spider biofilm induced || 1 -3.25 -3.21 -3.91 -3.69 -2.32 -3.20 0.62 -0.26 0.40 0.57 -2.97 -2.79 1.78 0.89 -0.97 -3.38
11445 || orf19.3859 || || || Putative microsomal beta-keto-reductase; transcript upregulated by treatment with ciclopirox olamine; induced by alpha pheromone in SpiderM medium; regulated by Sef1, Sfu1, and Hap43 || 1 -0.50 -0.65 -0.46 -0.18 -0.34 -0.52 -0.24 -0.01 0.10 -0.09 -0.61 -0.52 -0.31 0.22 -0.24 -0.68
11446 || orf19.5138 || IFA21 || || IPF family A protein; mutants are viable; Spider biofilm induced || 1 -0.81 -1.09 -1.72 0.08 -1.35 -1.37 0.42 0.96 1.00 0.83 -0.59 -0.87 0.04 0.60 -0.72 -1.63
11447 || orf19.3518 || || || Ortholog(s) have dicarboxylic acid transmembrane transporter activity, role in mitochondrial transport and mitochondrial inner membrane localization || 1 -0.56 -0.64 -0.14 -0.11 -0.46 -0.75 0.18 0.36 0.03 0.25 -0.79 -0.48 -0.46 -0.35 -0.10 -0.88
11448 || orf19.3931 || SFC1 || || Putative succinate-fumarate transporter; involved in repression of growth on sorbose; alkaline induced; rat catheter biofilm induced; Spider biofilm induced || 1 -0.78 -0.85 -1.61 -0.40 -2.81 -2.51 0.41 0.36 -0.05 0.71 -2.65 -1.79 -1.14 0.14 -0.01 -2.58
11449 || orf19.3931 || SFC1 || || Putative succinate-fumarate transporter; involved in repression of growth on sorbose; alkaline induced; rat catheter biofilm induced; Spider biofilm induced || 1 -0.80 -0.95 -1.51 -0.40 -2.28 -2.72 0.48 0.09 0.20 0.84 -1.65 -1.25 -0.65 -0.03 0.32 -2.09
11450 || orf19.3366 || CSH3 || || Functional homolog of S. cerevisiae Shr3p, which is a chaperone specific for amino acid permeases; localized to ER; required for wild-type amino-acid responsive hyphal growth and for mouse systemic virulence; regulated by Gcn2p and Gcn4p || 1 -0.29 -0.35 -0.22 -0.09 -0.72 -0.61 0.02 0.07 0.16 0.24 -0.47 -0.20 -0.28 0.15 0.12 -0.44
11451 || orf19.3749 || IFC3 || || Oligopeptide transporter; transcript induced by macrophage phagocytosis, BSA or peptides; fluconazole-induced; induced by Rim101 at pH 8; virulence-group-correlated expression; Hap43-repressed; Spider biofilm induced || 1 -1.60 -1.72 -0.64 -0.45 -3.38 -2.74 0.91 0.30 0.92 -0.11 -3.59 -2.14 -0.22 0.49 -1.24 -1.98
11452 || orf19.5121 || OPT5 || || Oligopeptide transporter; fungal-specific (no human or murine homolog); induced by BSA, but not by tetrapeptide or pentapeptide || 1 -1.55 -1.37 -1.00 -1.27 -2.42 -2.42 1.19 0.57 1.46 0.35 -3.07 -2.12 0.40 0.94 -1.44 -1.48
11453 || orf19.176 || OPT4 || || Oligopeptide transporter; detected at germ tube plasma membrane; transcript inducede during phagocytosis by macrophages; fungal-specific; Hap43-repressed; merged with orf19.2292 in Assembly 20; rat catheter and Spider biofilm induced || 1 -2.91 -2.93 -2.32 -2.27 -4.18 -3.72 1.23 0.71 1.23 0.04 -4.14 -3.10 0.14 1.12 -1.82 -3.15
11454 || orf19.176 || OPT4 || || Oligopeptide transporter; detected at germ tube plasma membrane; transcript inducede during phagocytosis by macrophages; fungal-specific; Hap43-repressed; merged with orf19.2292 in Assembly 20; rat catheter and Spider biofilm induced || 1 -4.44 -4.96 -3.92 -4.30 -5.78 -6.69 1.19 0.54 1.23 -0.17 -6.55 -5.80 0.12 0.76 -5.40 -5.14
11455 || orf19.176 || OPT4 || || Oligopeptide transporter; detected at germ tube plasma membrane; transcript inducede during phagocytosis by macrophages; fungal-specific; Hap43-repressed; merged with orf19.2292 in Assembly 20; rat catheter and Spider biofilm induced || 1 -4.47 -4.25 -3.49 -3.55 -5.59 -8.07 1.48 0.88 1.30 0.13 -6.57 -4.91 0.46 1.20 -6.01 -4.29
11456 || orf19.651 || LYP1 || || Putative permease; amphotericin B induced; flucytosine repressed; possibly an essential gene, disruptants not obtained by UAU1 method || 1 -0.82 -0.99 -0.52 -0.33 -1.34 -1.40 -0.00 -0.31 0.29 -0.20 -1.05 -0.68 -0.08 0.54 -0.87 -0.67
11457 || orf19.5138 || IFA21 || || IPF family A protein; mutants are viable; Spider biofilm induced || 1 -1.45 -1.34 -1.29 -1.12 -1.47 -2.07 0.56 0.80 0.43 0.61 -0.62 -0.79 -0.17 0.84 -0.98 -1.69
11458 || orf19.5138 || IFA21 || || IPF family A protein; mutants are viable; Spider biofilm induced || 1 -1.26 -1.13 -0.95 -0.63 -1.48 -2.18 0.31 0.56 0.49 0.37 -0.73 -0.79 -0.44 0.43 -1.16 -1.67
11459 || orf19.2706 || CRH11 || || GPI-anchored cell wall transglycosylase, putative ortholog of S. cerevisiae Crh1p; predicted glycosyl hydrolase domain; similar to Csf4p and to antigenic A. fumigatus Aspf9; predicted Kex2p substrate; caspofungin-induced || 1 -1.17 -1.25 -1.04 -0.75 -1.03 -2.35 0.53 0.64 0.13 0.66 -1.08 -1.50 -0.45 -0.07 -1.05 -0.80
11460 || orf19.6282 || || || Has domain(s) with predicted nucleic acid binding, nucleotide binding activity || 1 -1.33 -1.21 -1.36 -1.25 -1.52 -3.01 0.81 0.77 1.50 0.47 -1.66 -1.07 0.26 0.44 -1.31 -1.00
11461 || orf19.6282 || || || Has domain(s) with predicted nucleic acid binding, nucleotide binding activity || 1 -1.50 -1.27 -1.74 -2.03 -1.43 -4.14 0.97 0.98 1.42 0.64 -1.15 -1.44 0.29 0.34 -1.82 -1.10
11462 || orf19.6282 || || || Has domain(s) with predicted nucleic acid binding, nucleotide binding activity || 1 -0.83 -0.98 -1.33 -2.27 -1.31 -3.07 1.07 1.21 1.38 0.82 -1.34 -1.66 0.39 0.48 -1.31 -0.98
11463 || orf19.5557 || MNN4-4 || || Mannosyltransferase; transcript upregulated in Ssk1 response regulator mutant or in nik1 null mutant, but not in chk1 or sln1 null mutants; pheromone induced; Spider biofilm induced || 1 -1.30 -1.52 -2.57 -2.58 -1.52 -3.90 2.14 1.66 0.94 1.80 -1.18 -2.01 0.25 0.34 -2.47 -1.79
11464 || orf19.5280 || MUP1 || || Putative high affinity methionine permease; alkaline upregulated by Rim101; Spider biofilm induced || 1 -0.74 -0.73 -0.77 -0.84 -1.07 -1.99 0.26 0.12 0.04 0.40 -0.37 -0.37 0.34 1.34 -0.66 -0.63
11465 || orf19.3066 || ENG1 || || Endo-1,3-beta-glucanase; ortholog of S. cerevisiae Dse4 needed for cell separation; caspofungin, fluconazole repressed; repressed by alpha pheromone in SpiderM medium; flow model biofilm induced; rat catheter biofilm repressed || 1 -0.35 -0.58 -0.76 -0.10 -1.07 -1.65 -0.06 0.14 0.03 -0.14 -0.51 -0.54 0.20 0.76 -0.67 -0.35
11466 || orf19.4783 || || || Protein of unknown function; induced during chlamydospore formation in both C. albicans and C. dubliniensis || 1 -0.66 -0.80 -1.99 -0.77 -1.74 -2.40 -0.48 0.63 0.41 0.13 -0.15 -1.33 0.08 0.64 -1.34 -1.24
11467 || orf19.4783 || || || Protein of unknown function; induced during chlamydospore formation in both C. albicans and C. dubliniensis || 1 -0.44 -0.27 -1.10 -0.53 -0.61 -2.50 -0.67 -0.04 0.16 0.29 -0.08 -1.12 -0.17 1.20 -0.53 -0.74
11468 || orf19.1244 || GYP2 || || Ortholog(s) have Rab GTPase activator activity, role in intracellular protein transport and cell division site, cytosol localization || 1 -0.34 -0.34 -0.79 -0.97 -0.75 -1.03 -0.06 -0.12 -0.17 0.01 -0.32 -0.29 -0.14 0.22 -0.43 -0.45
11469 || orf19.341 || || || Putative spermidine export pump; fungal-specific (no human or murine homolog) || 1 0.04 -0.22 -1.59 -1.93 -1.02 -2.63 -0.10 -0.20 0.63 0.78 -1.47 -2.54 -0.36 0.16 -1.54 -2.29
11470 || orf19.341 || || || Putative spermidine export pump; fungal-specific (no human or murine homolog) || 1 -0.12 -0.20 -2.30 -2.46 -3.29 -3.06 -0.16 -0.63 0.55 0.81 -1.59 -2.25 -0.73 0.73 -2.50 -2.15
11471 || orf19.341 || || || Putative spermidine export pump; fungal-specific (no human or murine homolog) || 1 0.50 0.10 -1.85 -3.22 -2.56 -2.57 -0.23 -0.45 1.08 0.95 -1.79 -1.64 -0.54 0.82 -1.50 -2.20
11472 || orf19.318 || || || Ortholog(s) have role in iron-sulfur cluster assembly and mitochondrial matrix localization || 1 0.02 -0.12 -0.34 -0.45 -0.42 -0.56 0.12 0.22 0.32 0.17 -0.44 -0.25 -0.32 0.12 -0.29 -0.25
11473 || orf19.2303 || FGR16 || || Protein lacking an ortholog in S. cerevisiae; transposon mutation affects filamentous growth; fluconazole-downregulated || 1 -0.43 -0.35 -0.70 -0.77 -0.90 -0.79 -0.15 0.52 0.15 0.17 -0.69 -0.53 -0.05 -0.44 -0.64 -0.27
11474 || orf19.7392 || DED1 || || Predicted ATP-dependent RNA helicase; RNA strand annealing activity; Spider biofilm induced || 1 -0.68 -0.79 -1.00 -0.41 -0.83 -1.08 0.12 0.22 -0.71 0.45 -0.36 -1.02 0.10 -0.16 -0.56 -0.89
11475 || orf19.4045 || EST1 || || Telomerase subunit; allosteric activator of catalytic activity, but not required for catalytic activity; has TPR domain || 1 -0.52 -0.42 -0.39 -0.28 -0.45 -0.41 0.02 0.08 -0.16 -0.08 -0.28 -0.96 -0.00 -0.05 -0.62 -1.03
11476 || orf19.5339 || || || Ortholog of S. cerevisiae Spg5; required for proteasome assembly during quiescence; transcript detected on high-resolution tiling arrays; Spider biofilm induced || 1 -0.30 -0.14 -0.77 -0.47 -1.12 -0.89 -0.21 -0.36 -0.29 -0.48 -0.64 -1.28 0.38 -0.77 -0.87 -1.29
11477 || orf19.5526 || SEC20 || || Essential protein; similar to S. cerevisiae Sec20p; depletion causes membrane accumulation and drug sensitivity; expression regulated by growth phase; O-mannosylation regulates proteolysis; does not complement S. cerevisiae sec20-1 mutant || 1 -0.16 -0.42 -1.13 -0.22 -0.74 -0.75 -0.22 -0.16 0.03 -0.38 -0.52 -1.14 -0.23 0.14 -1.27 -0.84
11478 || orf19.5580 || TEL1 || || Ortholog(s) have protein serine/threonine kinase activity, telomeric DNA binding activity and role in DNA damage induced protein phosphorylation, double-strand break repair, histone phosphorylation, telomere maintenance || 1 -0.56 -0.52 -0.84 -0.34 -0.35 -0.55 -0.06 -0.36 -0.05 0.10 -0.98 -0.87 -0.09 -0.14 -0.55 -0.55
11479 || orf19.2475 || PGA26 || || GPI-anchored adhesin-like protein of the cell wall; role in cell wall integrity; required for normal virulence; induced in high iron and during cell wall regeneration; Hap43-repressed || 1 -0.27 -0.29 -1.45 -0.32 -0.40 -0.45 -0.73 -0.64 0.01 -0.13 -0.94 -1.44 -0.20 -0.22 -0.39 -1.33
11480 || orf19.716 || || || Protein of unknown function; Hap43-induced; regulated by Nrg1, Tup1; repressed by alpha pheromone in SpiderM medium; Spider biofilm induced; Bcr1-repressed in RPMI a/a biofilms || 1 -1.29 -1.41 -1.75 -1.92 -2.26 -1.91 -0.23 -0.14 0.97 0.34 -1.58 -0.46 0.87 -0.73 0.94 -3.06
11481 || orf19.716 || || || Protein of unknown function; Hap43-induced; regulated by Nrg1, Tup1; repressed by alpha pheromone in SpiderM medium; Spider biofilm induced; Bcr1-repressed in RPMI a/a biofilms || 1 -0.80 -0.65 -1.01 -0.92 -1.62 -1.45 0.18 0.37 1.68 0.89 -1.11 0.01 1.55 -0.72 1.03 -2.69
11482 || orf19.7089 || PMR1 || || Putative secretory pathway P-type Ca2+/Mn2+-ATPase; required for protein glycosylation and cell wall maintenance; required for hyphal tip oscillation in semisolid substrate; putative ortholog of S. cerevisiae PMR1 || 1 -0.15 -0.07 -0.42 0.17 -0.49 -0.70 -0.09 -0.14 0.20 0.25 -0.25 -0.16 0.53 -0.14 0.17 -0.34
11483 || orf19.2843 || RHO1 || || Small GTPase of Rho family; regulates beta-1,3-glucan synthesis activity and binds Gsc1p; essential; expected to be geranylgeranylated by geranylgeranyltransferase type I; plasma membrane-localized || 1 -0.11 -0.08 -0.27 0.15 -0.57 -1.17 -0.27 -0.15 0.21 0.16 -0.54 -0.28 0.22 0.33 -0.02 -0.64
11484 || orf19.2336 || || || Pry family pathogenesis-related protein; predicted to be extracellular || 1 -0.25 -0.33 -0.19 0.18 -1.04 -1.37 0.06 -0.10 -0.32 0.33 0.02 -0.65
11485 || orf19.2891 || || || Ortholog(s) have role in cellular response to oxidative stress, misfolded or incompletely synthesized protein catabolic process, protein import into peroxisome matrix and mitochondrial inner membrane localization || 1 -0.29 -0.34 -0.71 -0.38 -1.88 -2.10 -0.09 -0.64 -0.21 0.17 -1.01 -0.17 0.22 -0.27 -0.20 -0.88
11486 || orf19.1960 || CLN3 || || G1 cyclin; depletion abolishes budding and causes hyphal growth defects; farnesol regulated, functional in S. cerevisiae; possibly essential (UAU1 method); other biofilm induced; Spider biofilm induced || 1 -1.12 -1.33 -0.86 -1.11 -3.17 -2.68 0.07 -0.56 0.01 -0.45 -2.18 -0.80 0.63 -0.68 0.05 -1.16
11487 || orf19.1960 || CLN3 || || G1 cyclin; depletion abolishes budding and causes hyphal growth defects; farnesol regulated, functional in S. cerevisiae; possibly essential (UAU1 method); other biofilm induced; Spider biofilm induced || 1 -0.87 -1.04 -0.12 -0.21 -2.52 -2.18 0.37 0.00 0.53 0.02 -1.70 -0.06 0.76 -0.12 0.43 -0.38
11488 || orf19.4539 || || || Protein with a Rho GDP-dissociation inhibitor domain; Hap43-repressed gene; Spider biofilm induced || 1 -0.43 -0.58 -0.26 0.07 -0.83 -0.85 0.13 0.44 0.43 0.38 -0.61 -0.18 0.48 -0.31 -0.02 -0.24
11489 || orf19.7118 || || || Ortholog(s) have adenylate kinase activity, nucleoside triphosphate adenylate kinase activity, role in nucleotide metabolic process and mitochondrial inner membrane localization || 1 -0.09 -0.09 -0.14 -0.06 -0.74 -0.37 0.34 0.30 0.29 0.32 -0.42 -0.35 0.07 -0.27 -0.17 -0.38
11490 || orf19.3475 || || || Described as a Gag-related protein; hyphal induced; downregulation correlates with clinical development of fluconazole resistance; repressed by nitric oxide, 17-beta-estradiol, ethynyl estradiol || 1 0.04 -0.15 -0.26 0.20 -1.57 -1.26 0.16 -0.04 0.49 0.90 -0.98 -0.95 0.14 -0.68 0.16 -1.02
11491 || orf19.3475 || || || Described as a Gag-related protein; hyphal induced; downregulation correlates with clinical development of fluconazole resistance; repressed by nitric oxide, 17-beta-estradiol, ethynyl estradiol || 1 -0.14 -0.17 -0.69 0.04 -1.77 -1.37 0.35 -0.01 0.24 0.74 -0.85 -1.06 0.29 -0.89 0.26 -0.92
11492 || orf19.4583 || || || Protein with a mitochondrial carrier protein domain; possibly an essential gene, disruptants not obtained by UAU1 method; Spider biofilm repressed || 1 -0.20 -1.00 -0.22 -0.11 -1.80 -1.28 0.50 0.36 0.30 0.66 -0.54 -0.13 -0.35 -0.24 0.31 -0.70
11493 || orf19.3171 || ACH1 || || Acetyl-coA hydrolase; acetate utilization; nonessential; soluble protein in hyphae; antigenic in human; induced on polystyrene adherence; farnesol-, ketoconazole-induced; no human or murine homolog; stationary phase-enriched protein || 1 -1.28 -1.31 -0.84 -0.32 -0.65 -2.17 0.07 0.66 -0.48 0.77 -0.64 -1.09 -1.23 -0.31 -0.34 -0.85
11494 || orf19.3171 || ACH1 || || Acetyl-coA hydrolase; acetate utilization; nonessential; soluble protein in hyphae; antigenic in human; induced on polystyrene adherence; farnesol-, ketoconazole-induced; no human or murine homolog; stationary phase-enriched protein || 1 -1.25 -1.25 -1.09 -0.87 -0.62 -2.52 -0.12 0.60 -0.98 0.67 -0.94 -1.49 -1.48 -0.03 -0.70 -1.02
11495 || orf19.5271 || || || Protein of unknown function; Hap43-induced gene || 1 -0.37 -0.67 -0.89 -0.35 -0.32 -1.30 -0.05 0.22 -0.16 0.75 -0.28 -0.39 0.73 0.45 -0.15 -0.72
11496 || orf19.1673 || PPT1 || || Putative serine/threonine phosphatase; induced in high iron || 1 -0.14 -0.17 -1.03 -0.42 -0.51 -0.92 0.05 -0.16 -0.31 0.97 -0.36 -0.21 0.24 0.76 -0.14 -0.81
11497 || orf19.558 || GUT1 || || Putative glycerol kinase; downregulated upon adherence to polystyrene; greater mRNA abundance observed in a cyr1 homozygous null mutant than in wild type || 1 -0.45 -0.47 -0.74 -0.50 -0.53 -0.94 0.02 -0.35 -0.29 0.91 -0.59 -0.09 0.53 0.21 0.21 -1.32
11498 || orf19.558 || GUT1 || || Putative glycerol kinase; downregulated upon adherence to polystyrene; greater mRNA abundance observed in a cyr1 homozygous null mutant than in wild type || 1 -0.56 -0.62 -0.73 -0.51 -1.25 -1.09 0.13 -0.17 -0.22 1.02 -0.49 0.09 0.46 -0.00 0.26 -1.29
11499 || orf19.5919 || MEA1 || || Protein similar to A. nidulans MesA, which is involved in localization of actin cables; Hap43p-induced gene || 1 -0.44 -0.44 -0.32 -0.02 -0.44 -0.72 0.04 0.36 0.32 1.00 -0.37 -0.05 0.46 -0.06 -0.02 -1.03
11500 || orf19.5919 || MEA1 || || Protein similar to A. nidulans MesA, which is involved in localization of actin cables; Hap43p-induced gene || 1 0.11 -0.29 -0.40 0.35 -0.46 -0.56 -0.12 -0.03 0.39 0.98 -0.68 0.05 -0.03 0.26 -0.45 -0.63
11501 || orf19.5919 || MEA1 || || Protein similar to A. nidulans MesA, which is involved in localization of actin cables; Hap43p-induced gene || 1 0.04 -0.04 -0.69 -0.16 -0.13 -0.96 -0.09 0.10 0.60 0.94 -0.53 0.16 0.08 0.09 -0.24 -0.66
11502 || orf19.4161 || || || Ortholog(s) have role in DNA repair and Smc5-Smc6 complex, nucleus localization || 1 0.15 -0.03 -0.53 -0.05 -0.43 -1.17 0.02 0.29 -0.44 0.99 -0.49 0.34 -0.06 -0.05 -0.48 -0.96
11503 || orf19.4161 || || || Ortholog(s) have role in DNA repair and Smc5-Smc6 complex, nucleus localization || 1 0.14 -0.19 0.01 0.09 0.18 -1.05 -0.04 0.39 -0.13 1.05 -0.38 -0.13 0.05 0.13 -0.50 -0.94
11504 || orf19.4890 || CLA4 || || Ste20p family Ser/Thr kinase required for wild-type filamentous growth, organ colonization and virulence in mouse systemic infection; role in chlamydospore formation; functional homolog of S. cerevisiae Cla4p; mutant caspofungin sensitive || 1 -0.06 -0.32 -0.27 0.11 -0.57 -1.20 -0.20 -0.07 -0.11 0.52 -0.29 -0.38 0.30 -0.24 -0.22 -0.96
11505 || orf19.676 || || || Microtubule-binding protein of the cortical microtubule; delays exit from mitosis when the spindle is abnormally oriented; Spider biofilm repressed || 1 -0.43 -0.13 0.06 0.04 -0.29 -0.91 -0.33 0.01 0.02 0.52 -0.40 -0.25 -0.01 -0.17 -0.24 -0.87
11506 || orf19.1170 || ARO7 || || Putative chorismate mutase; fungal-specific (no human or murine homolog); alkaline upregulated || 1 -0.37 -0.32 -0.27 -0.12 -0.43 -0.98 -0.51 -0.18 0.10 0.57 -0.39 0.17 0.12 -0.43 -0.50 -0.76
11507 || orf19.634 || || || Ortholog of C. dubliniensis CD36 : Cd36_30370, Candida tropicalis MYA-3404 : CTRG_00536 and Candida albicans WO-1 : CAWG_01831 || 1 -0.70 -0.29 -0.32 0.13 -0.17 -1.62 -0.60 -0.17 -0.07 1.46 -0.13 -0.13 -0.07 0.47 -0.62
11508 || orf19.6693 || || || Ortholog(s) have cytosol, nucleus localization || 1 -0.08 0.03 -0.62 0.12 -0.65 -0.98 -0.08 0.23 0.55 1.12 -0.22 -0.42 -0.06 -0.85 -0.31 -0.89
11509 || orf19.7130 || || || Protein of unknown function; Hap43-repressed gene || 1 -0.01 0.01 -0.02 -0.49 -0.04 -1.94 0.66 0.31 0.55 0.38 -0.86 -0.45 -0.69 -0.25 -1.22 -1.54
11510 || orf19.4070 || || || Ortholog of C. dubliniensis CD36 : Cd36_23270 || 1 -0.13 0.02 -1.05 -0.51 0.65 -5.12 0.37 0.85 1.17 0.37 -2.50 -3.51 0.61 -0.37 -3.32 -3.12
11511 || orf19.7093 || HGT13 || || Predicted sugar transporter, involved in glycerol utilization; member of the major facilitator superfamily; 12 transmembrane; gene has intron; oxidative stress-induced via Cap1p; expressed in rich medium, 2% glucose || 1 -0.01 -0.48 0.12 -0.91 -0.98 -1.51 0.57 0.14 -0.17 1.35 -0.19 -0.31 -0.37 -0.20 -0.54 -0.44
11512 || orf19.7093 || HGT13 || || Predicted sugar transporter, involved in glycerol utilization; member of the major facilitator superfamily; 12 transmembrane; gene has intron; oxidative stress-induced via Cap1p; expressed in rich medium, 2% glucose || 1 -0.53 -0.72 -0.20 -1.62 -1.26 -1.36 0.01 -0.05 -0.44 1.07 -0.45 -0.76 0.23 -0.77 -1.11 -0.11
11513 || orf19.3865 || RFX1 || || Transcription factor; involved in DNA damage responses, morphogenesis, and virulence; Spider biofilm induced || 1 -0.24 -0.44 -1.07 -0.47 -0.14 -0.84 0.46 -0.32 0.12 0.27 -0.28 0.20 0.07 0.08 -0.01 -0.84
11514 || orf19.5599 || MDL2 || || Putative mitochondrial, half-size MDR-subfamily ABC transporter || 1 -0.12 -0.35 -0.57 -0.75 -0.29 -0.45 -0.07 0.15 0.08 0.20 -0.23 -0.08 -0.06 0.20 0.17 0.30
11515 || orf19.1106 || || || Protein with Mob2p-dependent hyphal regulation; fluconazole-induced || 1 -0.63 -0.36 -0.17 -1.18 -0.92 -0.16 0.33 0.06 -0.09 0.18 -0.29 0.21
11516 || orf19.1371 || || || Ortholog of C. dubliniensis CD36 : Cd36_23880, C. parapsilosis CDC317 : CPAR2_806590, Candida tenuis NRRL Y-1498 : CANTEDRAFT_92769 and Debaryomyces hansenii CBS767 : DEHA2B13376g || 1 -0.62 -0.59 -0.02 -0.84 -0.79 -0.74 -0.21 0.09 0.03 -0.14 0.17 0.38 -0.28 0.46 0.06 0.24
11517 || orf19.5508 || || || Ortholog of Candida albicans WO-1 : CAWG_05700 || 1 -0.73 -0.74 -0.30 -0.98 -0.44 -0.14 -0.00 -0.24 0.62 -0.07 -0.43 0.20 -0.11 0.58 0.02 0.69
11518 || orf19.5599 || MDL2 || || Putative mitochondrial, half-size MDR-subfamily ABC transporter || 1 -0.64 -0.61 -0.12 -0.68 -0.54 -0.67 0.05 -0.10 0.00 0.32 -0.26 0.03 -0.07 0.26 -0.17 0.38
11519 || orf19.4118 || CNT || || CNT family H(+)/nucleoside symporter; transports adenosine, uridine, inosine, guanosine, tubercidin; variant alleles for high/low-affinity isoforms; S or G at residue 328 affects specificity; Spider, flow model biofilm induced || 1 -0.66 -0.65 -0.30 -1.72 -0.42 -0.85 0.51 -0.24 0.39 0.30 -0.14 -0.12 0.37 0.44 -0.37 0.44
11520 || orf19.5489 || || || Ortholog of C. dubliniensis CD36 : Cd36_20660, C. parapsilosis CDC317 : CPAR2_104730, Candida tenuis NRRL Y-1498 : CANTEDRAFT_133951 and Debaryomyces hansenii CBS767 : DEHA2F02068g || 1 -0.65 -0.67 -0.39 -1.67 -0.66 -0.52 -0.07 -0.49 0.51 0.03 -0.20 0.25 -0.01 0.62 -0.47 -0.51
11521 || orf19.2910 || PGA43 || || Putative GPI-anchored protein || 1 -1.05 -0.93 -0.99 -0.59 -0.27 -0.29 -0.24 -0.18 0.40 -0.35 -0.06 0.17 0.09 0.94 -0.32 0.19
11522 || orf19.2910 || PGA43 || || Putative GPI-anchored protein || 1 -0.90 -1.00 -0.83 -0.56 -0.48 -0.52 -0.19 -0.25 0.48 -0.40 -0.28 -0.01 -0.01 0.68 -0.34 -0.28
11523 || orf19.931 || || || Ortholog of Candida albicans WO-1 : CAWG_04452 || 1 -0.65 -0.58 -0.06 -0.45 -0.56 -0.17 0.31 0.18 0.38 -0.70 -0.08 0.04 -0.09 0.15 0.03 0.28
11524 || orf19.5639 || HIS4 || || Multifunctional enzyme that catalyzes three steps of histidine biosynthesis, with phosphoribosyl-AMP cyclohydrolase, phosphoribosyl-ATP diphosphatase, and histidinol dehydrogenase activities; required for wild-type adhesion to human calls || 1 -0.43 -0.31 -0.47 -0.32 -0.43 -1.03 0.29 0.02 0.93 -0.49 -0.12 0.19 -0.32 0.17 -0.24 0.20
11525 || orf19.4012 || PCL5 || || Putative cyclin for Pho85 kinase; Gcn4-induced; suppresses toxicity of C. albicans Gcn4 overproduction in S. cerevisiae via increased Pho85-dependent phosphorylation and degradation of Gcn4; rat catheter and Spider biofilm induced || 1 -0.79 -0.73 -1.00 -0.85 -0.83 -0.85 0.72 -0.27 0.65 -1.50 -0.10 0.08 -0.71 0.39 -0.26 0.41
11526 || orf19.4012 || PCL5 || || Putative cyclin for Pho85 kinase; Gcn4-induced; suppresses toxicity of C. albicans Gcn4 overproduction in S. cerevisiae via increased Pho85-dependent phosphorylation and degradation of Gcn4; rat catheter and Spider biofilm induced || 1 -0.69 -0.76 -0.77 -1.13 -0.90 -0.86 0.67 -0.44 0.88 -1.52 -0.13 -0.20 -0.80 0.61 -0.42 0.29
11527 || orf19.597 || || || Protein with an aspartate aminotransferase domain; Gcn4-regulated || 1 -0.17 -0.23 -0.17 -0.29 -0.15 -0.11 0.12 -0.18 0.48 -0.60 -0.13 0.13 -0.46 -0.30 0.05
11528 || orf19.7292 || ARP2 || || Component of the Arp2/3 complex; required for virulence, hyphal growth, cell wall/cytoskeleton organization, not for endocytosis; mutation confers hypersensitivity to cytochalasin D; regulated by Gcn2 and Gcn4; Spider biofilm repressed || 1 -0.26 -0.51 -0.14 -0.20 -0.42 -0.30 -0.25 -0.01 0.15 -0.20 -0.07 0.11 -0.47 0.23 -0.33 0.35
11529 || orf19.2637 || || || Ortholog(s) have Golgi apparatus, fungal-type vacuole membrane localization || 1 -0.90 -1.29 0.09 -0.37 -0.87 -0.54 -0.37 0.16 0.29 -0.20 0.14 0.08 -0.57 0.22 -0.82 0.33
11530 || orf19.295 || || || Ortholog of C. dubliniensis CD36 : Cd36_82970, Lodderomyces elongisporus NRLL YB-4239 : LELG_02117, Debaryomyces hansenii CBS767 : DEHA2G01012g and Candida lusitaniae ATCC 42720 : CLUG_03529 || 1 -0.70 -0.85 -0.37 -0.29 -0.09 -0.05 0.07 0.08 0.21 -0.16 -0.12 -0.06 -0.26 0.23 -0.00 0.21
11531 || orf19.281 || || || Ortholog of C. dubliniensis CD36 : Cd36_82880, C. parapsilosis CDC317 : CPAR2_102370, Candida tenuis NRRL Y-1498 : CANTEDRAFT_118463 and Pichia stipitis Pignal : PICST_32241 || 1 -0.80 -0.75 -0.30 -0.27 -0.17 -0.26 -0.01 0.07 0.19 -0.10 -0.06 -0.12 -0.41 0.18 -0.05 0.50
11532 || orf19.6353 || || || Ortholog of Candida albicans WO-1 : CAWG_00172 || 1 -0.75 -0.61 -0.29 -0.27 -0.38 -0.38 0.22 0.36 0.60 -0.29 -0.14 0.17 -0.21 -0.11 -0.23 0.56
11533 || orf19.1063 || || || Ortholog(s) have dolichyl-phosphate-mannose-glycolipid alpha-mannosyltransferase activity, role in GPI anchor biosynthetic process and integral to endoplasmic reticulum membrane, mannosyltransferase complex, mitochondrion localization || 1 -1.19 -1.28 -0.98 -1.00 -0.34 -0.80 0.27 0.38 0.57 -0.12 0.53 0.38 -0.14 0.10 -0.71 0.73
11534 || orf19.3113 || || || Protein of unknown function; Spider biofilm induced || 1 -0.74 -0.90 -0.86 -0.84 -0.56 -0.15 0.59 -0.05 0.45 -0.19 0.02 0.33 -0.49 0.52 -0.59 0.67
11535 || orf19.3114 || || || Predicted pseudouridine synthase; Spider biofilm induced || 1 -0.46 -0.74 -0.29 -0.28 -0.42 -0.12 0.68 -0.03 0.59 -0.23 0.26 -0.02 -0.28 -0.03 -0.52 0.64
11536 || orf19.5211 || IDP1 || || Putative isocitrate dehydrogenase; transcriptionally induced by interaction with macrophage; alkaline induced; Spider biofilm repressed || 1 -0.75 -0.72 -0.30 0.10 -0.35 -0.89 0.55 0.36 0.38 -0.09 0.21 0.36 -0.71 0.25 -0.47 0.21
11537 || orf19.1792 || || || Ortholog(s) have ubiquitin-protein ligase activity || 1 -0.26 -0.37 0.25 0.20 -0.75 -1.12 0.19 0.53 -0.02 0.02 0.24 0.33 -0.03 0.69 -0.28 0.88
11538 || orf19.1988 || CDC45 || || Putative DNA replication initiation factor; transcriptionally regulated by interaction with macrophage || 1 -0.26 -0.38 0.23 -0.30 -0.84 -1.29 0.20 0.25 0.09 -0.11 0.79 0.42 0.22 0.62 -0.19 0.66
11539 || orf19.486 || NIP100 || || p150 subunit of dynactin; required for normal spindle formation and position || 1 -0.22 -0.29 -0.19 -0.33 -0.46 -0.88 0.24 0.03 0.12 -0.20 0.16 0.28 -0.06 0.34 -0.35 0.70
11540 || orf19.6971 || DIE2 || || Ortholog(s) have dolichyl-phosphate-glucose-glycolipid alpha-glucosyltransferase activity, role in protein N-linked glycosylation and endoplasmic reticulum membrane localization || 1 -0.52 -0.42 -0.44 -0.24 -0.76 -1.01 0.37 0.14 0.06 0.10 -0.32 0.44 0.03 0.60 -0.50 0.11
11541 || orf19.6971 || DIE2 || || Ortholog(s) have dolichyl-phosphate-glucose-glycolipid alpha-glucosyltransferase activity, role in protein N-linked glycosylation and endoplasmic reticulum membrane localization || 1 -0.36 -0.46 -0.42 -0.37 -0.98 -1.10 0.32 0.33 0.37 0.19 -0.26 0.46 -0.23 0.67 -0.85 0.19
11542 || orf19.6971 || DIE2 || || Ortholog(s) have dolichyl-phosphate-glucose-glycolipid alpha-glucosyltransferase activity, role in protein N-linked glycosylation and endoplasmic reticulum membrane localization || 1 -0.38 -0.52 -0.37 -0.18 -0.85 -1.05 0.33 0.16 0.08 0.22 -0.25 0.36 -0.21 0.70 -0.56 0.56
11543 || orf19.1110 || || || Thiamine pyrophosphokinase, phosphorylates thiamine to produce the coenzyme thiamine pyrophosphate (thiamine diphosphate); active as a homodimer || 1 -0.22 -0.29 -0.20 -0.47 -0.76 -0.35 0.10 0.07 0.11 -0.10 -0.16 0.35 -0.31 0.35 -0.26 0.41
11544 || orf19.2558 || || || Has domain(s) with predicted zinc ion binding activity and nucleus localization || 1 -0.12 -0.34 -0.08 -0.32 -0.71 -0.56 0.05 0.22 -0.21 0.15 0.22 0.29 -0.25 0.41 -0.19 0.24
11545 || orf19.2036 || || || Predicted dihydrodiol dehydrogenase; ortholog of S. pombe SPAC513.06c; flow model and rat catheter biofilm repressed || 1 -0.28 -0.00 -0.52 -0.06 -0.76 -0.89 -0.21 0.26 -0.08 0.44 0.35 0.24 0.26 0.45 -0.08 -0.66
11546 || orf19.2036 || || || Predicted dihydrodiol dehydrogenase; ortholog of S. pombe SPAC513.06c; flow model and rat catheter biofilm repressed || 1 -0.32 -0.48 -0.88 -0.31 -0.79 -0.94 -0.31 0.29 -0.44 0.41 0.35 0.20 0.08 0.41 0.09 -0.16
11547 || orf19.2746 || EMP70 || || Protein with a role in endosome-to-vacuole sorting; rat catheter biofilm repressed || 1 -0.22 -0.23 -0.11 -0.09 -0.21 -0.65 -0.19 0.12 -0.30 0.30 0.39 0.12 -0.04 0.23 0.14 -0.17
11548 || orf19.5209 || || || Ortholog(s) have role in CVT pathway, intra-Golgi vesicle-mediated transport and Golgi transport complex, cell division site, cytosol, nucleus localization || 1 -0.17 -0.12 -0.59 -0.36 -0.51 -0.88 -0.39 -0.06 -0.53 0.07 0.02 0.48 -0.39 0.27 -0.10 0.10
11549 || orf19.5147 || LMO1 || || Protein involved together with Dck1p and Rac1p in invasive filamentous growth and cell wall integrity; acts upstream of MAP kinase Cek1p; has similarity to human ELMO1 || 1 -0.30 -0.51 -0.66 -0.48 -0.32 -1.00 -0.57 0.00 -0.45 0.53 0.42 0.23 -0.25 -0.12 -0.13 -0.30
11550 || orf19.5291 || || || Ortholog(s) have role in phospholipid biosynthetic process and endoplasmic reticulum localization || 1 -0.32 -0.30 -0.60 -0.36 -0.74 -1.22 -0.59 -0.28 -0.40 0.35 0.12 0.19 -0.29 -0.13 0.54 -0.20
11551 || orf19.3797 || || || Ortholog(s) have structural constituent of ribosome activity and mitochondrial large ribosomal subunit localization || 1 -0.34 -0.35 -0.73 -0.51 -0.73 -1.00 -0.46 -0.25 0.16 0.23 -0.26 0.08 -0.31 0.09 0.12 -0.17
11552 || orf19.6803 || HUT1 || || Ortholog(s) have UDP-galactose transmembrane transporter activity, role in UDP-galactose transmembrane transport, UDP-glucose transport, regulation of protein folding in endoplasmic reticulum and endoplasmic reticulum localization || 1 -0.12 -0.33 -0.29 -0.60 -0.83 -1.45 -0.18 0.59 -0.49 0.87 -0.13 0.49 0.04 0.01 0.05 0.19
11553 || orf19.2203 || || || Ortholog of Candida albicans WO-1 : CAWG_05873 || 1 -0.27 -0.43 -1.00 -1.35 -0.49 1.09 -1.17 0.36 0.68 -0.66 -0.34 0.55
11554 || orf19.2278 || || || Putative 20S proteasome assembly protein; filament induced; induced by alpha pheromone in SpiderM medium || 1 -0.21 -0.36 -0.36 -0.18 -0.38 -0.52 -0.21 0.19 -0.38 -0.06 0.82 0.18 -0.51 -0.33 -0.19 0.18
11555 || orf19.2194 || || || Phosphorylated protein of unknown function || 1 -0.22 -0.22 -0.11 -0.08 -0.28 -0.54 -0.07 0.06 -0.16 -0.05 0.53 0.02 -0.27 -0.01 -0.08 0.12
11556 || orf19.4829 || DOA1 || || WD repeat protein; required for ubiquitin-mediated protein degradation; role in control of cellular ubiquitin levels; may promote efficient NHEJ in postdiauxic/stationary phase; Spider biofilm repressed || 1 -0.37 -0.29 -0.49 -0.26 -1.02 -0.92 -0.09 0.47 -0.05 -0.19 0.60 0.35 -0.72 -0.25 0.04 0.72
11557 || orf19.5369 || || || Uroporphyrinogen decarboxylase; catalyzes the 5th step in the heme biosynthetic pathway; flow model and Spider biofilm repressed || 1 -0.21 -0.29 -0.35 -0.18 -0.64 -1.01 0.13 0.41 -0.12 0.09 0.87 0.56 -0.58 -0.34 -0.05 0.61
11558 || orf19.861 || CAP4 || || Predicted bZip transcription factor; possibly an essential gene, disruptants not obtained by UAU1 method || 1 -0.00 -0.06 -0.46 -0.45 -0.76 -0.99 0.00 0.38 -0.40 -0.04 0.53 0.50 -0.29 -0.47 -0.17 0.34
11559 || orf19.861 || CAP4 || || Predicted bZip transcription factor; possibly an essential gene, disruptants not obtained by UAU1 method || 1 0.09 0.00 -0.67 -0.70 -1.01 -0.90 -0.16 0.24 -0.35 -0.21 0.91 0.61 -0.45 -0.23 -0.15 0.70
11560 || orf19.3307 || || || Flavin-containing monooxygenase; catalyzes oxidation of biological thiols to maintain the ER redox buffer ratio for correct folding of disulfide-bonded proteins; Spider biofilm repressed || 1 -0.20 -0.33 -0.05 -0.26 -0.67 -0.67 -0.07 -0.03 0.15 -0.48 0.36 0.31 -0.61 -0.04 -0.38 0.53
11561 || orf19.3811 || GYP1 || || Putative Cis-golgi GTPase-activating protein; transcript regulated by Nrg1, Mig1, and Tup1 || 1 -0.83 -0.70 -0.15 -0.11 -0.88 -0.54 -0.41 0.06 0.05 -0.51 0.49 0.53 -0.83 -0.19 -0.38 0.64
11562 || orf19.3811 || GYP1 || || Putative Cis-golgi GTPase-activating protein; transcript regulated by Nrg1, Mig1, and Tup1 || 1 -0.74 -0.45 -0.46 -0.35 -0.87 -0.91 -0.28 -0.05 0.12 -0.44 0.50 0.21 -0.68 -0.54 -0.17 0.46
11563 || orf19.393 || APS3 || || Component of the adaptor complex AP-3, which is involved in vacuolar protein sorting || 1 -0.44 -0.42 -0.61 -0.33 -0.94 -0.68 -0.14 -0.13 -0.12 -0.23 0.12 0.18 -0.70 0.17 -0.09 0.66
11564 || orf19.3128 || || || Ortholog(s) have syntaxin binding activity and role in ER to Golgi vesicle-mediated transport, positive regulation of SNARE complex assembly, retrograde vesicle-mediated transport, Golgi to ER, vesicle fusion with Golgi apparatus || 1 -0.31 -0.35 -0.18 -0.41 -0.76 -0.79 -0.32 0.03 -0.01 0.07 0.24 0.09 -0.56 0.15 -0.31 0.61
11565 || orf19.315 || || || Ortholog of C. dubliniensis CD36 : Cd36_83120, C. parapsilosis CDC317 : CPAR2_103220, Candida tenuis NRRL Y-1498 : CANTEDRAFT_112860 and Debaryomyces hansenii CBS767 : DEHA2G08360g || 1 -0.18 -0.09 -0.24 -0.13 -0.56 -0.73 -0.29 -0.02 -0.25 -0.11 0.42 0.10 -0.46 0.23 -0.29 0.48
11566 || orf19.3128 || || || Ortholog(s) have syntaxin binding activity and role in ER to Golgi vesicle-mediated transport, positive regulation of SNARE complex assembly, retrograde vesicle-mediated transport, Golgi to ER, vesicle fusion with Golgi apparatus || 1 -0.80 -0.52 -0.45 -0.02 -1.20 -0.61 -0.37 0.10 -0.16 0.06 0.11 0.19 -0.50 -0.16 -0.31 0.33
11567 || orf19.2923 || || || Predicted membrane transporter, member of the drug:proton antiporter (14 spanner) (DHA2) family, MFS superfamily; induced by alpha pheromone in SpiderM medium || 1 0.02 -0.44 -0.06 -0.20 -1.43 -1.04 -0.18 -0.43 -0.30 -0.62 0.27 0.81 -0.37 -0.50 -0.50 0.38
11568 || orf19.184 || MDM10 || || Predicted component of the mitochondrial sorting and assembly machinery (SAM complex) and ER-mitochondria encounter structure (ERMES) complex with a role in protein import into mitochondria || 1 0.06 -0.10 -0.08 -0.14 -0.54 -0.37 0.16 -0.15 -0.00 -0.24 0.17 0.19 -0.02 0.02 -0.09 0.20
11569 || orf19.2618 || MET2 || || Homoserine acetyltransferase; Hap43p-, Gcn4p-regulated; macrophage/pseudohyphal-repressed; not highly biofilm induced, in contrast to many sulfur amino acid metabolic genes; no human or murine homolog; virulence-group-correlated expression || 1 -0.31 -0.35 -0.11 -0.41 -1.46 -1.41 0.05 -0.39 0.37 -0.69 0.23 0.07 -0.48 -0.13 -0.04 0.44
11570 || orf19.4633 || || || Ortholog(s) have carbonyl reductase (NADPH) activity, oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor activity and cytosol, nucleus, ribosome localization || 1 -0.38 -0.43 -0.05 -0.04 -0.59 -0.68 0.07 0.10 0.42 -0.07 0.04 0.20 -0.73 -0.06 -0.58 0.03
11571 || orf19.2637 || || || Ortholog(s) have Golgi apparatus, fungal-type vacuole membrane localization || 1 -0.50 -0.50 -0.22 -0.20 -0.98 -0.65 -0.03 0.16 0.50 -0.25 0.14 0.39 -0.47 0.00 -0.57 0.16
11572 || orf19.4026 || HIS1 || || ATP phosphoribosyl transferase; enzyme of histidine biosynthesis; acid upregulated/alkaline repressed by Rim101; regulated by Gcn2, Gcn4; strain CA9 is a his1 mutant; flow model biofilm induced; Spider biofilm repressed || 1 -0.52 -0.63 -1.23 -0.95 -1.50 -1.43 0.72 0.26 0.23 -0.29 0.57 0.26 -1.35 -0.16 -1.13 0.25
11573 || orf19.4026 || HIS1 || || ATP phosphoribosyl transferase; enzyme of histidine biosynthesis; acid upregulated/alkaline repressed by Rim101; regulated by Gcn2, Gcn4; strain CA9 is a his1 mutant; flow model biofilm induced; Spider biofilm repressed || 1 -0.32 -0.42 -0.83 -0.41 -1.50 -1.14 0.87 0.43 0.51 -0.20 0.81 0.63 -1.19 -0.01 -0.70 0.56
11574 || orf19.4026 || HIS1 || || ATP phosphoribosyl transferase; enzyme of histidine biosynthesis; acid upregulated/alkaline repressed by Rim101; regulated by Gcn2, Gcn4; strain CA9 is a his1 mutant; flow model biofilm induced; Spider biofilm repressed || 1 -0.51 -0.62 -0.87 -0.31 -1.89 -1.38 0.78 0.45 0.35 -0.43 0.71 0.33 -1.55 -0.19 -1.05 0.49
11575 || orf19.4026 || HIS1 || || ATP phosphoribosyl transferase; enzyme of histidine biosynthesis; acid upregulated/alkaline repressed by Rim101; regulated by Gcn2, Gcn4; strain CA9 is a his1 mutant; flow model biofilm induced; Spider biofilm repressed || 1 -0.18 -0.21 -0.48 -0.01 -1.55 -1.13 0.93 0.60 0.42 -0.23 0.77 0.40 -1.15 -0.23 -0.98 0.04
11576 || orf19.4026 || HIS1 || || ATP phosphoribosyl transferase; enzyme of histidine biosynthesis; acid upregulated/alkaline repressed by Rim101; regulated by Gcn2, Gcn4; strain CA9 is a his1 mutant; flow model biofilm induced; Spider biofilm repressed || 1 -0.43 -0.52 -0.75 -0.18 -1.73 -1.57 0.56 0.37 0.41 -0.33 0.62 0.01 -1.62 -0.44 -1.17 -0.10
11577 || orf19.4633 || || || Ortholog(s) have carbonyl reductase (NADPH) activity, oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor activity and cytosol, nucleus, ribosome localization || 1 0.03 -0.05 -0.36 -0.20 -0.66 -0.66 0.37 0.21 0.21 -0.24 0.10 0.03 -0.50 -0.25 -0.54 -0.02
11578 || orf19.1065 || SSA2 || || HSP70 family chaperone; cell wall fractions; antigenic; beta-defensin peptides impport; ATPase domain binds histatin 5; at hyphal surface, not yeast; farnesol-repressed in biofilm; flow model, Spider biofilm repressed; caspofungin repressed || 1 0.08 0.05 -0.93 -0.75 -1.92 -1.14 0.58 0.58 -0.09 0.03 0.61 0.30 -0.48 -0.25 -0.76 0.11
11579 || orf19.1065 || SSA2 || || HSP70 family chaperone; cell wall fractions; antigenic; beta-defensin peptides impport; ATPase domain binds histatin 5; at hyphal surface, not yeast; farnesol-repressed in biofilm; flow model, Spider biofilm repressed; caspofungin repressed || 1 0.23 0.20 -0.49 -0.30 -1.87 -1.01 0.70 0.89 0.15 0.32 0.56 0.46 -0.42 -0.04 -0.74 0.28
11580 || orf19.4952.1 || || || Ortholog(s) have FK506 binding, Hsp70 protein binding, chaperone binding, peptidyl-prolyl cis-trans isomerase activity, role in protein complex assembly and cytoplasm, nucleus localization || 1 -0.10 -0.28 -0.61 -0.41 -0.51 -0.77 0.53 0.91 0.10 -0.19 0.75 0.12 -0.31 0.08 -0.61 0.01
11581 || orf19.5445 || GLO3 || || Putative ARF GTPase activator; role in COPI coating of Golgi vesicle, ER to Golgi vesicle-mediated transport, retrograde Golgi to ER vesicle-mediated transport; Spider biofilm repressed || 1 -0.06 -0.03 -0.54 -0.33 -0.73 -0.99 0.60 0.87 0.07 0.22 0.67 0.09 -0.26 -0.11 0.04 0.14
11582 || orf19.5493 || GSP1 || || Small RAN G-protein; essential; no prenylation predicted; can rescue S. cerevisiae gsp1 viability; macrophage/pseudohyphal-induced; transcript not regulated by white-opaque, yeast-hypha switching; GlcNAc-induced; Spider biofilm repressed || 1 -0.17 -0.34 -0.70 -0.32 -0.74 -0.72 0.50 0.70 -0.10 0.18 0.75 0.29 0.15 -0.34 -0.39 -0.00
11583 || orf19.3590 || IPP1 || || Putative inorganic pyrophosphatase; antigenic; soluble protein in hyphae; macrophage-induced protein; protein present in exponential and stationary phase yeast; possibly essential (UAU1 method); sumoylation target; Spider biofilm repressed || 1 -0.34 -0.38 -0.37 0.07 -0.80 -0.93 0.62 0.64 0.05 -0.06 0.75 0.34 0.07 -0.03 -0.20 0.01
11584 || orf19.2760 || || || Putative mRNA cleavage and polyadenylation factor; heterozygous null mutant exhibits hypersensitivity to parnafungin and cordycepin in the C. albicans fitness test || 1 -0.42 -0.40 -0.41 0.02 -0.39 -0.76 -0.02 -0.00 -0.20 0.14 0.21 0.08 -0.09 -0.01 -0.38 0.26
11585 || orf19.1110 || || || Thiamine pyrophosphokinase, phosphorylates thiamine to produce the coenzyme thiamine pyrophosphate (thiamine diphosphate); active as a homodimer || 1 -0.43 0.03 -0.70 -0.47 -0.99 -0.86 0.21 -0.00 -0.18 -0.34 0.35 0.08 -0.19 -0.10 0.04 0.37
11586 || orf19.1514 || || || Ortholog(s) have enzyme binding, phosphatidylinositol-4-phosphate binding activity and role in endoplasmic reticulum unfolded protein response, protein localization to Golgi apparatus, retrograde vesicle-mediated transport, Golgi to ER || 1 -0.49 -0.49 -0.28 -0.42 -0.89 -0.83 -0.29 0.05 0.12 0.27 0.31 0.22 0.05 0.01 -0.48 -0.28
11587 || orf19.5827 || BUB2 || || Ortholog(s) have GTPase activator activity, role in mitotic spindle orientation checkpoint, negative regulation of septation initiation signaling cascade and cytosol, mitotic spindle pole body, nucleus localization || 1 -0.88 -0.62 -0.09 0.15 -1.82 -1.28 -0.41 0.08 0.38 0.09 -0.46 -0.05 -0.32 -0.02 -1.11 0.06
11588 || orf19.5089 || TERT || || Telomerase reverse transcriptase; catalytic protein subunit of telomere synthesis; essential for telomerase activity; has telomerase-specific motif T and other conserved reverse transcriptase motifs || 1 -0.47 -0.53 -0.12 0.17 -0.90 -0.82 0.00 -0.00 0.41 -0.02 -0.25 0.10 -0.22 0.09 -0.49 -0.20
11589 || orf19.5089 || TERT || || Telomerase reverse transcriptase; catalytic protein subunit of telomere synthesis; essential for telomerase activity; has telomerase-specific motif T and other conserved reverse transcriptase motifs || 1 -0.58 -0.71 -0.28 -0.22 -0.79 -0.92 0.09 -0.08 0.39 -0.12 -0.35 -0.18 -0.16 0.25 -0.62 0.16
11590 || orf19.5027 || LCB2 || || Putative serine palmitoyltransferase component; mutation confers hypersensitivity to aureobasidin A || 1 -0.75 -0.90 -0.69 -0.21 -1.00 -1.02 0.19 0.08 -0.19 0.23 -0.37 -0.23 0.01 0.01 -0.49 -0.15
11591 || orf19.4716 || GDH3 || || NADP-glutamate dehydrogenase; Nrg1, Plc1 regulated; hypha, hypoxia, Efg1-repressed; Rim101-induced at pH 8; GlcNAc, ciclopirox, ketoconazole induced; exp and stationary phase protein; Spider biofilm repressed; rat catheter biofilm induced || 1 -1.82 -1.73 -1.08 0.05 -3.41 -2.78 0.63 -0.09 0.23 -0.28 -0.69 -0.84 0.00 0.31 0.11 -0.09
11592 || orf19.4716 || GDH3 || || NADP-glutamate dehydrogenase; Nrg1, Plc1 regulated; hypha, hypoxia, Efg1-repressed; Rim101-induced at pH 8; GlcNAc, ciclopirox, ketoconazole induced; exp and stationary phase protein; Spider biofilm repressed; rat catheter biofilm induced || 1 -1.95 -1.87 -0.70 0.06 -3.68 -2.77 0.81 0.11 0.31 -0.05 -0.44 -0.68 -0.01 0.46 -0.11 -0.11
11593 || orf19.6086 || LEU4 || || Putative 2-isopropylmalate synthase; regulated by Nrg1, Mig1, Tup1, Gcn4; induced by human whole blood or PMNs; macrophage/pseudohyphal-repressed after 16h; Spider biofilm repressed || 1 -1.22 -1.24 -0.96 -0.67 -2.67 -1.44 0.84 0.22 0.70 0.26 -0.57 -0.34 -0.99 0.21 -0.34 -0.17
11594 || orf19.1742 || HEM3 || || Hydroxymethylbilane synthase; converts 4-porphobilinogen to hydroxymethylbilane in heme biosynthesis; induced in high iron, CO2; alkaline repressed; regulated by Sef1, Sfu1, and Hap43; rat catheter and Spider biofilm induced || 1 -0.92 -0.73 -0.51 -0.10 -2.27 -1.11 0.51 -0.37 0.15 0.48 -0.51 0.22 -0.53 0.22 -0.85 -0.40
11595 || orf19.7370 || || || Possible G-protein coupled receptor; vacuolar membrane transporter for cationic amino acids; PQ-loop motif; rat catheter and Spider biofilm induced || 1 -1.30 -1.71 -1.07 -1.17 -2.76 -1.75 0.88 0.30 1.38 0.11 -0.05 0.32 0.68 0.30 -0.69 -0.38
11596 || orf19.511 || || || Ortholog(s) have ribosylnicotinamide kinase activity, role in NAD biosynthesis via nicotinamide riboside salvage pathway, nicotinamide riboside metabolic process and cytosol, nucleus localization || 1 -0.64 -0.74 -1.03 0.03 -1.22 -0.55 0.06 0.08 0.38 -0.03 -0.02 0.24 -0.43 0.18 -0.25 -0.15
11597 || orf19.7370 || || || Possible G-protein coupled receptor; vacuolar membrane transporter for cationic amino acids; PQ-loop motif; rat catheter and Spider biofilm induced || 1 -0.56 -0.55 -0.42 -0.32 -0.76 -1.31 0.34 0.14 0.64 -0.28 -0.05 0.09 0.07 0.45 -0.43 -0.28
11598 || orf19.5827 || BUB2 || || Ortholog(s) have GTPase activator activity, role in mitotic spindle orientation checkpoint, negative regulation of septation initiation signaling cascade and cytosol, mitotic spindle pole body, nucleus localization || 1 -0.48 -0.38 -0.47 -0.37 -1.00 -1.17 0.49 0.70 0.34 0.24 -0.20 0.08 0.56 0.29 -0.03 0.09
11599 || orf19.6282 || || || Has domain(s) with predicted nucleic acid binding, nucleotide binding activity || 1 -1.03 -1.01 -0.43 -2.37 -2.77 -4.46 2.24 1.16 1.88 0.96 -0.72 -0.41 1.21 0.88 -1.34 -0.63
11600 || orf19.1326 || || || Ortholog of Candida albicans WO-1 : CAWG_03455 || 1 -0.25 -0.25 -0.70 -0.56 -0.86 -1.34 0.42 0.38 0.56 0.22 -0.15 0.11 0.42 0.49 -0.47 -0.59
11601 || orf19.1326 || || || Ortholog of Candida albicans WO-1 : CAWG_03455 || 1 -0.44 -0.42 -0.86 -0.46 -1.24 -2.03 0.42 0.54 0.75 0.50 0.09 0.51 0.36 0.61 -0.40 -0.51
11602 || orf19.6022 || NRM1 || || Transcriptional regulator of cell cycle gene expression; regulates expression of genes involved in DNA replication stress; interacts with Swi4 and Swi6; repressed during core stress response; Spider biofilm repressed || 1 -0.46 -0.34 -0.88 -0.81 -1.97 -3.66 0.91 1.01 0.54 0.61 0.22 0.26 1.02 0.25 -1.14 -0.76
11603 || orf19.1742 || HEM3 || || Hydroxymethylbilane synthase; converts 4-porphobilinogen to hydroxymethylbilane in heme biosynthesis; induced in high iron, CO2; alkaline repressed; regulated by Sef1, Sfu1, and Hap43; rat catheter and Spider biofilm induced || 1 -0.12 -0.15 -0.60 -0.34 -1.62 -1.42 1.27 0.48 0.39 0.66 0.17 0.27 0.21 0.40 -0.42 -0.71
11604 || orf19.5661 || PTC7 || || Protein phosphatase, type 2C; has S/T phosphatase activity, Mn2+/Mg2+ dependent; predicted membrane-spanning segment and mitochondrion-targeting signal || 1 -0.31 -0.12 -0.60 -0.65 -0.87 -0.41 0.56 0.44 0.73 0.27 0.26 0.03 0.03 0.40 -0.34 -0.30
11605 || orf19.4060 || ARO4 || || 3-deoxy-D-arabinoheptulosonate-7-phosphate synthase; aromatic amino acid biosynthesis; GCN-regulated; feedback-inhibited by tyrosine if produced in S. cerevisiae Aro3p and Aro4p catalyze same reaction; protein decreases in stationary phase || 1 -0.65 -0.60 -1.46 -0.87 -1.38 -1.32 1.07 0.70 0.69 0.21 0.78 0.31 -0.89 0.10 -0.73 -0.10
11606 || orf19.4060 || ARO4 || || 3-deoxy-D-arabinoheptulosonate-7-phosphate synthase; aromatic amino acid biosynthesis; GCN-regulated; feedback-inhibited by tyrosine if produced in S. cerevisiae Aro3p and Aro4p catalyze same reaction; protein decreases in stationary phase || 1 -0.36 -0.37 -1.17 -0.53 -1.21 -1.22 1.27 0.82 0.82 0.19 0.81 0.18 -0.60 -0.04 -0.50 0.16
11607 || orf19.2422 || ARC1 || || Putative G4 nucleic acid binding protein; macrophage/pseudohyphal-repressed; protein enriched in stationary phase yeast-form cultures; Spider biofilm repressed || 1 -0.89 -0.95 -1.33 -0.69 -0.80 -0.74 1.07 1.07 0.49 0.52 1.10 0.32 -0.26 0.22 -0.42 0.42
11608 || orf19.1295 || VAS1 || || Putative tRNA-Val synthetase; genes encoding ribosomal subunits, translation factors, and tRNA synthetases are downregulated upon phagocytosis by murine macrophage || 1 -0.46 -0.51 -1.17 -0.78 -0.89 -1.16 1.15 1.25 0.47 0.59 1.10 0.42 -0.30 0.03 -0.35 0.23
11609 || orf19.1649 || RNA1 || || Putative GTPase-activating protein; protein level decreases in stationary phase cultures; Spider biofilm repressed || 1 -0.28 -0.28 -0.81 -0.70 -0.47 -0.43 0.58 0.67 0.29 0.66 0.78 0.23 -0.15 0.46 -0.35 0.17
11610 || orf19.1053 || || || Ortholog(s) have phosphatidylinositol deacylase activity || 1 -0.39 -0.47 -0.49 -0.41 -0.69 -0.78 0.34 0.29 0.31 0.30 0.19 0.10 0.35 0.36 -0.22 0.35
11611 || orf19.4528 || || || Ortholog(s) have role in vacuolar protein processing and endoplasmic reticulum localization || 1 -0.34 -0.33 -0.24 -0.34 -0.77 -1.03 0.60 0.43 0.58 0.04 0.43 0.09 0.42 0.41 -0.29 0.22
11612 || orf19.4731 || || || Ortholog(s) have role in CVT pathway, intra-Golgi vesicle-mediated transport and Golgi transport complex localization || 1 -0.25 -0.27 -0.72 -0.86 -0.75 -1.15 1.05 0.83 0.95 0.48 0.60 0.18 0.74 1.22 -0.41 -0.08
11613 || orf19.4731 || || || Ortholog(s) have role in CVT pathway, intra-Golgi vesicle-mediated transport and Golgi transport complex localization || 1 -0.47 -0.41 -0.75 -1.00 -1.08 -1.54 0.89 1.27 0.77 0.43 0.13 -0.31 0.57 0.89 -0.57 -0.51
11614 || orf19.6779 || PRO2 || || Putative gamma-glutamyl phosphate reductase with a predicted role in proline biosynthesis; regulated by Gcn2p and Gcn4p || 1 -0.28 -0.26 -1.07 -0.69 -0.64 -1.71 0.93 0.89 0.89 0.09 0.32 -0.26 -0.23 0.35 -0.31 -0.26
11615 || orf19.6994 || BAT22 || || Putative branched chain amino acid aminotransferase; regulated by Gcn4p; induced by farnesol treatment, GlcNAc, amino acid starvation (3-aminotriazole treatment); present in exponential and stationary growth phase yeast cultures || 1 -0.51 -0.55 -0.86 -0.67 -0.73 -0.88 0.90 0.84 0.68 0.10 0.33 0.14 -0.16 0.55 -0.35 -0.05
11616 || orf19.3365 || DAO2 || || Putative D-amino acid oxidase; rat catheter biofilm induced || 1 -1.14 -1.00 -1.08 -1.28 -1.04 -2.16 1.77 0.67 1.14 -0.14 0.37 0.03 0.14 1.01 -0.26 -0.01
11617 || orf19.6755 || DLD2 || || Ortholog(s) have D-lactate dehydrogenase (cytochrome) activity, role in aerobic respiration, cellular carbohydrate metabolic process and mitochondrial inner membrane localization || 1 -0.60 -0.77 -0.95 -0.47 -0.96 -1.58 0.92 0.61 1.02 -0.21 0.09 -0.26 0.09 0.27 -0.56 0.30
11618 || orf19.6082 || || || Ortholog(s) have unfolded protein binding activity, role in protein folding, protein localization to cell surface and integral to endoplasmic reticulum membrane, mitochondrial outer membrane localization || 1 -0.63 -0.49 -0.73 -0.68 -0.70 -0.71 0.77 0.59 0.33 0.15 0.15 -0.25 0.17 0.39 -0.25 0.32
11619 || orf19.6082 || || || Ortholog(s) have unfolded protein binding activity, role in protein folding, protein localization to cell surface and integral to endoplasmic reticulum membrane, mitochondrial outer membrane localization || 1 -0.48 -0.39 -0.71 -0.64 -0.56 -0.64 1.09 0.85 0.62 0.11 0.19 -0.40 0.43 0.52 -0.47 0.31
11620 || orf19.434 || PRD1 || || Putative proteinase; transcript regulated by Nrg1, Mig1, and Tup1; Hogp-induced; stationary phase enriched protein; Hap43-repressed; rat catheter biofilm repressed || 1 -0.43 -0.55 -1.04 -0.82 -0.37 -0.70 1.29 1.41 0.81 -0.18 0.24 -0.18 0.51 0.44 -0.12 0.13
11621 || orf19.4172 || || || Has domain(s) with predicted hydrolase activity and role in metabolic process || 1 -0.19 -0.14 -0.47 -0.57 -0.70 -0.89 0.95 0.81 0.88 -0.14 0.28 0.18 -0.11 0.44 -0.75 0.00
11622 || orf19.5054 || || || Putative quinolinate phosphoribosyl transferase, involved in NAD biosynthesis; Hap43p-repressed gene || 1 -0.25 -0.15 -0.23 -0.22 -0.28 -0.81 0.37 0.68 0.62 0.22 0.14 0.38 0.02 0.53 -0.26 0.06
11623 || orf19.5564 || || || Ortholog(s) have nucleolus localization || 1 -0.17 -0.22 -0.52 -0.28 -0.71 -1.55 0.45 1.02 0.63 0.82 0.53 0.23 -0.02 0.86 -0.45 -0.14
11624 || orf19.5901 || PKC1 || || Protein kinase C; functional homolog of S. cerevisiae Pkc1p; mutant has abnormal yeast-form cell morphology and increased cell lysis; activated by phosphatidylserine; target of antifungal, cercosporamide; R400P mutant is activated || 1 -0.17 -0.03 -0.50 -0.28 -0.67 -1.17 0.43 0.62 0.63 0.26 0.11 0.12 -0.16 0.42 -0.59 -0.02
11625 || orf19.1177 || || || Ortholog of S. cerevisiae Rtt106; histone chaperone that regulates chromatin structure in transcribed and silenced chromosomal regions; affects transcriptional elongation; Hap43-repressed; Spider biofilm repressed || 1 -0.19 -0.19 -0.56 -0.32 -0.15 -0.91 0.32 0.54 0.44 0.47 0.31 0.06 -0.39 0.13 -0.23 0.20
11626 || orf19.6579 || || || Ortholog of C. dubliniensis CD36 : Cd36_71340, C. parapsilosis CDC317 : CPAR2_301350, Candida tenuis NRRL Y-1498 : CANTEDRAFT_114098 and Debaryomyces hansenii CBS767 : DEHA2D03432g || 1 -0.05 0.02 -1.49 -0.60 -0.74 -1.46 0.33 0.67 0.65 0.97 0.77 -0.06 -0.18 0.27 -0.71 0.19
11627 || orf19.7428 || APN1 || || Ortholog of S. cerevisiae Apn1; an AP endonuclease; transcript induced by interaction with macrophages; fungal-specific (no human or murine homolog) || 1 -0.04 -0.18 -0.51 -0.34 -0.58 -1.03 0.23 0.43 0.40 0.59 0.56 -0.05 -0.00 0.05 -0.30 -0.16
11628 || orf19.2138 || ILS1 || || Putative isoleucyl-tRNA synthetase, the target of drugs including the cyclic beta-amino acid icofungipen/PLD-118/BAY-10-8888 and mupirocin; protein present in exponential and stationary growth phase yeast cultures || 1 -0.22 -0.39 -0.85 -0.61 -0.88 -1.32 0.75 0.82 0.84 0.56 0.41 0.16 0.05 -0.04 -0.59 0.26
11629 || orf19.2754 || TIM13 || || Predicted mitochondrial intermembrane space protein with a role in protein import into mitochondria || 1 -0.57 -0.50 -1.07 -1.07 -1.01 -1.55 1.50 1.55 0.76 0.95 1.00 0.28 0.72 0.70 -0.46 -0.18
11630 || orf19.6344 || RBK1 || || Ortholog(s) have cytosol, nucleus localization || 1 -0.29 -0.21 -0.84 -0.36 -0.43 -0.88 0.98 0.83 0.28 0.60 0.44 -0.06 0.51 0.25 -0.09 0.07
11631 || orf19.2560 || CDC60 || || Cytosolic leucyl tRNA synthetase; conserved amino acid and ATP binding class I signature, tRNA binding, proofreading motifs; likely essential for growth; interacts with benzoxaborole antifungals; present in exponential and stationary phase || 1 -0.25 -0.28 -0.65 -0.74 -0.56 -1.24 0.91 0.85 0.45 0.76 0.50 0.01 0.17 0.28 -0.08 0.45
11632 || orf19.2257 || || || Predicted ER protein involved in ER-nucleus signaling; Spider biofilm repressed || 1 -0.68 -0.34 -1.12 -0.61 -0.76 -1.59 0.61 0.93 0.28 0.51 0.67 -0.17 -0.06 0.13 -0.10 -0.22
11633 || orf19.7383 || MNN9 || || Protein of N-linked outer-chain mannan biosynthesis; mutant has defective cell wall; required for wild-type hyphal growth; mutant is hygromycin B sensitive and vanadate resistant; has N-terminal membrane-spanning segment (positions 18-34) || 1 -0.21 -0.26 -1.15 -0.71 -0.73 -1.58 0.68 1.00 -0.10 0.58 0.49 -0.15 0.40 0.19 0.16 -0.46
11634 || orf19.7383 || MNN9 || || Protein of N-linked outer-chain mannan biosynthesis; mutant has defective cell wall; required for wild-type hyphal growth; mutant is hygromycin B sensitive and vanadate resistant; has N-terminal membrane-spanning segment (positions 18-34) || 1 -0.29 -0.36 -0.86 -0.38 -0.88 -1.48 0.63 0.97 0.04 0.86 0.58 0.31 0.27 0.45 0.08 -0.15
11635 || orf19.7631 || SLD5 || || Putative GINS complex subunit; cell-cycle regulated periodic mRNA expression || 1 -0.31 -0.54 -0.34 -0.33 -0.67 -1.29 0.37 0.81 0.12 0.88 0.49 0.43 0.25 0.15 -0.32 -0.17
11636 || orf19.5281 || || || Predicted essential RNA-binding G protein; ortholog an effector of mating response pathway in S. cerevisiae; mainly associated with nuclear envelope and ER; flow model and Spider biofilm repressed || 1 -0.99 -0.98 -0.91 -0.38 -0.94 -1.03 0.86 0.67 -0.08 0.40 0.67 0.36 0.27 -0.18 -0.27 0.51
11637 || orf19.1516 || || || Ortholog(s) have ubiquitin-specific protease activity || 1 -0.79 -0.90 -0.60 -0.19 -0.85 -0.92 0.28 0.04 0.02 0.25 0.26 0.48 -0.20 0.07 -0.19 0.90
11638 || orf19.7263 || || || Putative X-Pro aminopeptidase; Spider biofilm repressed || 1 -0.35 -0.37 -0.28 -0.22 -0.44 -0.43 0.25 0.12 -0.11 -0.11 0.12 0.05 -0.28 0.10 -0.01 0.32
11639 || orf19.3133 || GUT2 || || Glycerol-3-phosphate dehydrogenase; Plc1p-regulated; rat catheter biofilm induced; Spider biofilm induced || 1 -0.93 -0.70 -0.83 -0.62 -1.16 -0.61 0.41 -0.10 -0.20 0.14 0.27 -0.38 -0.25 0.73 -0.69 -0.18
11640 || orf19.6402 || CYS3 || || Cystathionine gamma-lyase; induced by alkaline, amphotericin B, cadmium stress, oxidative stress via Cap1; possibly adherence-induced; Hog1 regulated; reduced levels in stationary phase yeast cells; Spider and flow model biofilm induced || 1 -0.72 -0.91 -0.91 -0.37 -1.95 -1.05 0.26 -0.15 -0.49 0.54 0.62 -0.44 -0.31 0.08 -0.50 -0.33
11641 || orf19.6402 || CYS3 || || Cystathionine gamma-lyase; induced by alkaline, amphotericin B, cadmium stress, oxidative stress via Cap1; possibly adherence-induced; Hog1 regulated; reduced levels in stationary phase yeast cells; Spider and flow model biofilm induced || 1 -0.58 -0.77 -1.24 -0.79 -1.79 -1.14 0.45 -0.09 -0.61 0.43 0.62 -0.61 -0.43 -0.06 -0.30 -0.38
11642 || orf19.3590 || IPP1 || || Putative inorganic pyrophosphatase; antigenic; soluble protein in hyphae; macrophage-induced protein; protein present in exponential and stationary phase yeast; possibly essential (UAU1 method); sumoylation target; Spider biofilm repressed || 1 -0.54 -0.50 -0.37 0.09 -1.02 -1.02 0.17 0.23 -0.16 -0.14 0.22 -0.33 -0.48 -0.37 -0.58 -0.16
11643 || orf19.5211 || IDP1 || || Putative isocitrate dehydrogenase; transcriptionally induced by interaction with macrophage; alkaline induced; Spider biofilm repressed || 1 -0.92 -0.96 -0.77 -0.51 -1.30 -1.61 0.48 0.23 0.02 -0.66 0.13 -0.40 -0.72 -0.63 -0.96 -0.10
11644 || orf19.3590 || IPP1 || || Putative inorganic pyrophosphatase; antigenic; soluble protein in hyphae; macrophage-induced protein; protein present in exponential and stationary phase yeast; possibly essential (UAU1 method); sumoylation target; Spider biofilm repressed || 1 -0.52 -0.41 -0.64 -0.28 -1.02 -1.15 0.29 0.28 -0.15 -0.22 0.30 0.18 -0.25 -0.28 -0.49 -0.22
11645 || orf19.2269 || || || Putative 3-phosphoserine phosphatase; induced by benomyl or in azole-resistant strain that overexpresses MDR1; early-stage flow model biofilm induced; Spider biofilm repressed || 1 -0.64 -0.69 -0.62 -0.15 -1.46 -1.49 -0.07 0.15 -0.17 -0.67 0.49 0.25 -0.46 0.07 -0.67 0.17
11646 || orf19.2269 || || || Putative 3-phosphoserine phosphatase; induced by benomyl or in azole-resistant strain that overexpresses MDR1; early-stage flow model biofilm induced; Spider biofilm repressed || 1 -0.91 -1.11 -1.12 -0.85 -1.83 -1.46 0.03 0.10 -0.47 -0.77 0.47 0.37 -0.64 0.21 -0.91 0.56
11647 || orf19.3802 || PMT6 || || Protein mannosyltransferase; required for virulence in mice, adhesion to endothelium; role in hyphal growth signaling, hygromycin B sensitivity; no major role in cellular PMT activity; Hap4-repressed; Bcr1-repressed in RPMI a/a biofilms || 1 -0.72 -0.84 -0.36 -0.63 -0.73 -1.34 -0.02 0.43 -0.30 -0.51 0.33 0.37 -0.36 -0.11 -0.21 0.29
11648 || orf19.1063 || || || Ortholog(s) have dolichyl-phosphate-mannose-glycolipid alpha-mannosyltransferase activity, role in GPI anchor biosynthetic process and integral to endoplasmic reticulum membrane, mannosyltransferase complex, mitochondrion localization || 1 -1.22 -1.22 -1.03 -1.61 -0.61 -1.15 -0.41 0.30 0.10 -0.17 0.36 0.27 -0.29 0.41 -0.73 0.60
11649 || orf19.1808 || MED5 || || RNA polymerase II mediator complex subunit; transcription positively regulated by Tbf1p || 1 -0.92 -1.01 -0.74 -1.28 -0.88 -0.94 -0.12 -0.11 0.23 0.03 0.25 0.46 -0.09 0.21 -0.10 0.58
11650 || orf19.6905 || || || Ortholog of S. cerevisiae : YNL011C, C. glabrata CBS138 : CAGL0H03619g, C. dubliniensis CD36 : Cd36_71090, C. parapsilosis CDC317 : CPAR2_300420 and Candida tenuis NRRL Y-1498 : CANTEDRAFT_111980 || 1 -1.15 -1.03 -0.86 -1.34 -1.37 -1.51 0.08 0.02 0.06 -0.53 0.37 -0.13 -0.44 0.12 -0.19 0.60
11651 || orf19.3407 || RAD18 || || Putative transcription factor with zinc finger DNA-binding motif; Hap43p-repressed gene || 1 -0.47 -0.73 -0.36 -0.57 -0.47 -0.64 0.01 0.18 -0.01 -0.00 0.41 -0.03 -0.20 0.06 -0.32 0.31
11652 || orf19.2790 || SWD2 || || Ortholog(s) have histone methyltransferase activity (H3-K4 specific) activity || 1 -1.08 -1.42 -0.61 -1.25 -0.58 -1.26 -0.03 0.36 -0.30 -0.32 0.33 -0.19 -0.33 -0.32 -0.19 0.27
11653 || orf19.1155 || DPP2 || || Protein similar to S. cerevisiae pyrophosphate phosphatase Lpp1p; possible role in farnesol biosynthesis || 1 -1.44 -2.95 -2.46 -2.12 -2.30 -2.87 -0.52 0.53 -0.23 0.05 0.49 0.26 0.02 -0.06 -0.20 0.58
11654 || orf19.6045 || || || Putative phosphatidylserine decarboxylase; involved in phosphatidylethanolamine; Spider biofilm repressed || 1 -0.47 -0.46 -0.39 -0.72 -0.52 -1.10 0.14 0.31 0.19 -0.13 -0.03 0.04 0.12 0.13 0.04 0.25
11655 || orf19.5932 || || || Protein of unknown function; Spider biofilm induced || 1 -1.08 -1.23 -0.91 -1.67 -1.27 -1.86 -0.11 -0.25 -0.11 -0.11 -0.19 0.18 0.11 0.41 0.08 0.19
11656 || orf19.2454 || PHO87 || || Putative phosphate permease; transcript repressed by Rim101 at pH 8; regulated by white-opaque switch; caspofungin repressed; virulence-group-correlated expression; flow model biofilm induced || 1 -1.90 -2.08 -2.57 -3.09 -2.46 -4.07 0.65 0.27 0.50 -0.27 -0.48 0.09 0.10 0.25 -0.03 0.05
11657 || orf19.2454 || PHO87 || || Putative phosphate permease; transcript repressed by Rim101 at pH 8; regulated by white-opaque switch; caspofungin repressed; virulence-group-correlated expression; flow model biofilm induced || 1 -2.89 -3.13 -3.31 -3.53 -3.12 -4.56 0.61 0.17 0.75 -0.20 -0.47 0.04 0.03 0.35 -0.62 -0.21
11658 || orf19.5496 || AVT1 || || Putative vacuolar transporter; promoter bound by a1p and alpha2p by ChIP-chip analysis || 1 -0.98 -1.42 -1.31 -1.20 -1.26 -1.54 0.32 0.22 0.23 0.38 -0.15 0.19 0.21 0.22 -0.26 0.26
11659 || orf19.413.1 || RPS27A || || Ribosomal protein S27; rat catheter and Spider biofilm induced || 1 -1.78 -1.94 -2.02 -1.66 -2.35 -2.10 0.62 -0.17 0.21 -0.28 -0.33 -0.08 0.62 1.03 -0.12 -0.35
11660 || orf19.413.1 || RPS27A || || Ribosomal protein S27; rat catheter and Spider biofilm induced || 1 -0.94 -0.74 -1.24 -1.27 -0.98 -1.49 0.67 -0.04 0.11 -0.32 -0.08 0.03 0.62 0.81 0.06 -0.17
11661 || orf19.4118 || CNT || || CNT family H(+)/nucleoside symporter; transports adenosine, uridine, inosine, guanosine, tubercidin; variant alleles for high/low-affinity isoforms; S or G at residue 328 affects specificity; Spider, flow model biofilm induced || 1 -1.29 -1.45 -1.30 -1.43 -1.13 -1.07 0.46 -0.23 -0.08 0.07 -0.44 -0.31 0.31 0.27 -0.56 0.52
11662 || orf19.5932 || || || Protein of unknown function; Spider biofilm induced || 1 -2.29 -2.17 -3.52 -3.06 -1.53 -2.74 -0.52 -0.66 -0.25 -0.47 -0.70 0.15 0.05 -0.31 0.04 0.26
11663 || orf19.6872 || || || Putative protein of unknown function; Hap43p-repressed gene || 1 -1.24 -1.05 -1.73 -1.38 -1.26 -1.01 0.74 0.28 -0.19 -0.73 0.43 -0.20 0.25 -0.03 -0.55 0.42
11664 || orf19.6872 || || || Putative protein of unknown function; Hap43p-repressed gene || 1 -0.80 -1.05 -0.95 -0.88 -1.14 -0.63 0.71 0.47 0.17 -0.29 0.59 0.29 0.33 0.22 -0.38 0.61
11665 || orf19.923 || THR1 || || Putative homoserine kinase; regulated by Tup1; amphotericin B repressed; regulated by Gcn2 and Gcn4; Spider biofilm repressed || 1 -1.54 -1.59 -2.03 -2.18 -2.39 -1.89 0.99 0.73 0.45 -0.57 0.94 0.41 0.14 0.37 -0.57 0.84
11666 || orf19.923 || THR1 || || Putative homoserine kinase; regulated by Tup1; amphotericin B repressed; regulated by Gcn2 and Gcn4; Spider biofilm repressed || 1 -1.36 -1.38 -1.77 -1.86 -2.24 -2.04 1.17 1.12 0.64 -0.52 0.98 0.40 0.55 0.32 -0.46 0.66
11667 || orf19.2381 || || || Protein of unknown function; possibly an essential gene, disruptants not obtained by UAU1 method || 1 -0.49 -0.62 -0.83 -1.08 -0.99 -0.95 0.40 0.32 0.23 -0.34 0.38 0.23 0.45 0.25 -0.33 0.53
11668 || orf19.1235 || HOM3 || || Putative L-aspartate 4-P-transferase; fungal-specific (no human or murine homolog); regulated by Gcn2 and Gcn4; early-stage flow model biofilm induced || 1 -1.11 -1.30 -1.65 -2.15 -2.13 -1.14 1.32 0.60 1.01 -0.84 0.22 0.45 0.11 0.44 -0.39 0.96
11669 || orf19.1235 || HOM3 || || Putative L-aspartate 4-P-transferase; fungal-specific (no human or murine homolog); regulated by Gcn2 and Gcn4; early-stage flow model biofilm induced || 1 -1.09 -1.17 -1.48 -2.01 -2.46 -1.52 0.98 0.34 0.40 -1.15 -0.25 -0.26 0.04 -0.11 -0.89 0.10
11670 || orf19.6905 || || || Ortholog of S. cerevisiae : YNL011C, C. glabrata CBS138 : CAGL0H03619g, C. dubliniensis CD36 : Cd36_71090, C. parapsilosis CDC317 : CPAR2_300420 and Candida tenuis NRRL Y-1498 : CANTEDRAFT_111980 || 1 -0.69 -0.52 -0.71 -1.11 -1.12 -1.39 0.29 0.33 0.16 -0.61 0.44 -0.03 0.15 -0.00 -0.04 0.44
11671 || orf19.247 || || || Ortholog(s) have role in endosome organization, regulation of protein localization and BLOC-1 complex, endosome localization || 1 -0.30 -0.47 -0.96 -1.10 -1.21 -1.53 0.25 0.21 -0.14 -0.43 0.41 -0.23 0.24 -0.10 -0.02 0.43
11672 || orf19.2844 || APL4 || || Predicted gamma-adaptin, large subunit of the clathrin-associated protein (AP-1) complex; that binds clathrin and is involved in vesicle mediated transport; induced in core caspofungin response; rat catheter biofilm repressed || 1 -0.39 -0.45 -0.93 -1.06 -0.53 -1.33 0.47 0.11 -0.70 -0.51 0.58 -0.32 -0.09 -0.45 -0.27 0.23
11673 || orf19.5493 || GSP1 || || Small RAN G-protein; essential; no prenylation predicted; can rescue S. cerevisiae gsp1 viability; macrophage/pseudohyphal-induced; transcript not regulated by white-opaque, yeast-hypha switching; GlcNAc-induced; Spider biofilm repressed || 1 -0.83 -0.64 -1.08 -0.80 -0.96 -0.82 0.24 0.17 -0.56 -0.13 0.56 -0.19 -0.20 -0.47 -0.61 -0.03
11674 || orf19.4605 || TYR1 || || Putative prepephenate dehydrogenase; enzyme of tyrosine biosynthesis; fungal-specific (no human or murine homolog) || 1 -0.67 -0.65 -1.08 -1.16 -0.60 -1.10 0.33 0.21 -0.20 -0.03 0.31 -0.24 -0.35 -0.55 -0.42 -0.13
11675 || orf19.4149 || || || Predicted protein of unknown function; overlaps orf19.4149.1 || 1 -0.74 -1.22 -1.25 -1.47 -1.28 -1.80 0.50 0.79 -0.70 -0.08 0.29 0.06 -0.49 -0.37 -0.34 0.52
11676 || orf19.5796 || SHE9 || || Protein with similarity to S. cerevisiae She9p, which inhibits growth when overproduced; gene has possible growth-regulation element; fungal-specific (no human or murine homolog) || 1 -0.44 -0.60 -0.87 -0.94 -0.62 -0.97 0.11 0.39 -0.34 -0.34 0.30 -0.07 -0.28 -0.15 0.08 0.28
11677 || orf19.2558 || || || Has domain(s) with predicted zinc ion binding activity and nucleus localization || 1 -0.30 -0.30 -0.64 -0.73 -0.65 -0.84 0.24 0.32 -0.37 -0.15 0.59 -0.00 -0.20 -0.09 -0.14 -0.04
11678 || orf19.3168 || RPN8 || || Putative regulatory subunit of the 26S proteasome; mutation confers hypersensitivity to amphotericin B; regulated by Mig1, Gcn2 and Gcn4; Spider biofilm repressed || 1 -0.35 -0.40 -0.89 -0.63 -0.96 -0.92 0.17 0.13 -0.68 -0.30 0.48 0.08 -0.50 -0.24 0.06 0.30
11679 || orf19.3027 || || || Putative DNA translocase; Spider biofilm repressed || 1 -0.57 -0.55 -0.78 -0.85 -0.66 -0.88 -0.20 0.02 -0.52 -0.40 0.40 -0.09 -0.39 -0.01 0.14 0.17
11680 || orf19.2041 || || || Ortholog(s) have DNA translocase activity, histone acetyl-lysine binding activity || 1 -0.85 -0.93 -1.13 -1.26 -1.12 -1.36 -0.14 -0.10 -0.56 -0.61 0.37 -0.05 0.02 -0.10 -0.28 0.16
11681 || orf19.4209 || || || Ortholog(s) have NEDD8 activating enzyme activity, role in protein neddylation and cytosol, nucleus localization || 1 -0.36 -0.56 -0.60 -0.75 -0.55 -0.73 -0.14 -0.05 -0.46 -0.26 0.18 -0.18 -0.13 0.23 -0.33 0.04
11682 || orf19.4517 || || || Protein of unknown function; Hap43-induced gene || 1 -1.01 -0.83 -2.36 -1.39 -1.61 -1.80 -0.09 0.39 -1.19 0.46 0.72 0.08 -0.29 0.46 -0.45 -0.52
11683 || orf19.4641 || NMT1 || || Myristoyl-CoA:protein N-myristoyltransferase; attaches the fatty acid myristate to a small number of proteins at an N-terminal Gly; essential; antifungal drug target; functional homolog of S. cerevisiae Nmt1p || 1 -0.72 -0.65 -1.41 -1.12 -0.90 -1.54 -0.12 0.14 -0.76 0.02 0.39 0.28 -0.55 0.32 -0.37 0.15
11684 || orf19.6789 || || || S. cerevisiae ortholog Nud1 is a spindle pole body outer plaque component; it acts through the mitotic exit network to specify asymmetric spindle pole body inheritance; Hap43-induced gene || 1 -0.49 -0.38 -1.17 -1.05 -0.78 -1.43 -0.31 0.43 -0.72 -0.22 0.27 -0.10 -0.05 0.51 -0.90 -0.03
11685 || orf19.6032 || SPE1 || || Ornithine decarboxylase; enzyme of polyamine biosynthesis; mutant is viable; functionally complements polyamine auxotrophy of S. cerevisiae spe1 mutant; downregulated upon adherence to polystyrene || 1 -0.23 -0.33 -1.23 -1.03 -0.97 -1.73 0.13 0.14 -0.22 -0.12 0.17 0.00 -0.33 0.07 -0.28 -0.02
11686 || orf19.2930 || || || Predicted translation initiation factor; role in translational initiation; Spider biofilm repressed || 1 -0.58 -0.71 -0.48 -0.22 -0.53 -1.30 0.17 0.14 -0.16 0.19 0.00 -0.01 -0.13 -0.36 -0.19 -0.11
11687 || orf19.1170 || ARO7 || || Putative chorismate mutase; fungal-specific (no human or murine homolog); alkaline upregulated || 1 -1.20 -1.52 -1.14 -0.65 -1.52 -1.94 -0.16 0.36 0.10 0.67 0.51 0.38 0.01 -0.49 -0.28 -0.44
11688 || orf19.5280 || MUP1 || || Putative high affinity methionine permease; alkaline upregulated by Rim101; Spider biofilm induced || 1 -1.75 -1.86 -2.38 -2.11 -3.39 -3.15 1.03 0.51 -0.22 0.19 0.17 -0.51 0.57 1.52 -0.94 -1.18
11689 || orf19.1233 || ADE4 || || Putative phosphoribosylpyrophosphate amidotransferase; flucytosine induced || 1 -0.35 -0.34 -1.19 -0.95 -1.42 -1.53 0.32 0.52 0.19 0.62 0.03 -0.50 0.18 0.56 -0.32 -0.34
11690 || orf19.1092 || || || Dolichol-P-Man dependent alpha(1-3) mannosyltransferase; role in the synthesis of dolichol-linked oligosaccharide donor for N-linked glycosylation of proteins; rat catheter biofilm repressed || 1 -0.28 -0.38 -0.80 -0.78 -1.35 -1.12 0.06 0.25 0.05 0.32 0.01 0.19 -0.14 0.44 -0.56 -0.13
11691 || orf19.4341 || || || Ortholog(s) have role in attachment of GPI anchor to protein, conidium formation, hyphal growth, sporocarp development involved in sexual reproduction and GPI-anchor transamidase complex localization || 1 -0.54 -0.65 -0.29 -0.08 -1.39 -1.46 0.09 0.32 0.02 0.43 0.07 -0.08 0.11 0.14 -0.58 -0.05
11692 || orf19.587 || || || Ortholog(s) have transcription export complex localization || 1 -0.65 -0.70 -0.42 -0.60 -1.43 -1.83 0.12 0.36 -0.09 0.22 0.18 0.12 -0.32 0.49 -0.83 -0.26
11693 || orf19.7549 || PMT5 || || Protein mannosyltransferase (PMT), expressed at extremely low levels; not required for wild-type hyphal growth, drug resistance, or virulence in mouse systemic infection; one of five PMT family members || 1 -0.86 -0.84 -0.61 -0.70 -1.41 -2.32 0.46 0.51 0.41 0.60 0.00 -0.08 -0.44 0.47 -0.83 -0.38
11694 || orf19.685 || YHM1 || || Putative mitochondrial carrier protein; fungal-specific (no human or murine homolog); Hap43p-repressed gene || 1 -0.62 -0.88 -0.73 -0.52 -1.47 -1.45 0.24 0.44 0.72 0.31 -0.32 -0.17 -0.09 -0.18 -0.80 -0.44
11695 || orf19.685 || YHM1 || || Putative mitochondrial carrier protein; fungal-specific (no human or murine homolog); Hap43p-repressed gene || 1 -0.80 -0.84 -0.65 -0.46 -1.63 -1.42 0.22 0.10 0.52 0.46 -0.37 -0.24 -0.32 0.08 -0.67 -0.48
11696 || orf19.6022 || NRM1 || || Transcriptional regulator of cell cycle gene expression; regulates expression of genes involved in DNA replication stress; interacts with Swi4 and Swi6; repressed during core stress response; Spider biofilm repressed || 1 -1.32 -1.47 -1.22 -1.05 -2.89 -2.86 0.25 0.05 0.53 0.58 -0.64 0.27 -0.06 0.24 -1.73 -1.01
11697 || orf19.5423 || EST3 || || Telomerase subunit; required for telomere maintenance in vivo; separable roles in telomerase activity and processivity; not required for catalytic activity in vitro; related to mammalian Tpp1p || 1 -1.12 -0.99 -0.80 -0.83 -1.44 -1.41 0.18 0.25 0.52 0.27 -0.71 -0.23 -0.31 0.28 -1.38 -0.54
11698 || orf19.1591 || ERG10 || || Acetyl-CoA acetyltransferase; role in ergosterol biosynthesis; soluble in hyphae; changes in protein abundance associated with azole resistance; fluconazole or ketoconazole induced; macrophage-downregulated protein; GlcNAc-induced protein || 1 -0.76 -0.68 -0.75 -0.43 -1.12 -1.61 0.02 0.18 0.42 0.09 -0.14 -0.14 -0.03 0.20 -1.43 -0.28
11699 || orf19.6180 || || || Protein similar to Pichia anomala YDL054c and S. cerevisiae Ydl054cp; transmembrane regions predicted; Hap43p-repressed gene || 1 -0.68 -0.88 -0.18 -0.18 -0.87 -0.87 -0.12 -0.05 0.14 -0.32 -0.29 -0.23 -0.35 -0.04 -0.50 -0.25
11700 || orf19.1881 || || || Putative broad-specificity lysophospholipid acyltransferase; role in glycerophospholipid biosynthesis; rat catheter biofilm repressed || 1 -0.67 -0.78 -0.33 -0.42 -0.98 -0.74 -0.01 -0.18 -0.13 -0.33 -0.29 -0.23 -0.41 -0.07 -0.55 -0.23
11701 || orf19.6109 || TUP1 || || Transcriptional corepressor; represses filamentous growth; regulates switching; role in germ tube induction, farnesol response; in repression pathways with Nrg1, Rfg1; farnesol upregulated in biofilm; rat catheter, Spider biofilm repressed || 1 -0.68 -0.70 -0.07 -0.20 -1.11 -0.81 0.04 -0.16 -0.04 -0.25 -0.03 -0.05 -0.28 -0.18 -0.56 0.03
11702 || orf19.1690 || TOS1 || || Protein similar to alpha agglutinin anchor subunit; secreted; exogenously expressed protein is a substrate for Kex2 processing in vitro; fluconazole-induced; induced by alpha pheromone in SpiderM medium; Hap43-induced || 1 -1.40 -1.43 -0.84 -0.35 -1.99 -1.84 -0.54 -0.18 -0.16 0.19 0.04 -0.24 -0.17 -0.66 -1.06 -0.34
11703 || orf19.6538 || VMA11 || || Predicted ortholog of S. cerevisiae Tfp3/Vma11; c' subunit of the V0 subcomplex of the vacuolar ATPase; required for hemoglobin-iron utilization; Spider biofilm repressed || 1 -1.28 -1.40 -0.79 -0.39 -2.31 -1.73 -0.48 -0.24 -0.65 -0.31 -0.36 -0.22 -0.41 -0.10 -0.90 -0.94
11704 || orf19.1683 || PPH21 || || Putative protein phosphatase of the Type 2A-related family (serine/threonine-specific), similar to S. cerevisiae Pph21p; caspofungin repressed; possibly an essential gene, disruptants not obtained by UAU1 method || 1 -0.57 -0.71 -0.54 -0.51 -1.74 -1.72 -0.15 0.21 -0.18 -0.40 -0.07 -0.37 -0.52 -0.39 -1.13 -0.58
11705 || orf19.2036 || || || Predicted dihydrodiol dehydrogenase; ortholog of S. pombe SPAC513.06c; flow model and rat catheter biofilm repressed || 1 -0.59 -0.68 -0.43 -0.28 -0.89 -1.07 -0.32 0.30 -0.27 0.30 0.00 0.08 -0.42 0.06 -0.14 -0.36
11706 || orf19.7327 || PHO88 || || Protein with a role in phosphate transport; biofilm-regulated expression; amphotericin B repressed || 1 -1.34 -1.50 -1.40 -0.61 -2.44 -2.77 -0.25 0.59 -0.67 0.65 0.49 0.02 -0.87 -0.01 -0.55 -0.45
11707 || orf19.1372 || || || Protein of unknown function; transcript regulated by Mig1 and Tup1 || 1 -1.10 -1.23 -1.05 -0.68 -1.33 -1.95 -0.18 0.29 -0.20 0.18 0.27 0.18 -0.55 0.14 -0.48 -0.48
11708 || orf19.6026 || ERG2 || || C-8 sterol isomerase; enzyme of ergosterol biosynthesis; converts fecosterol to episterol; mutant is hypersensitive to multiple drugs; ketoconazole-induced; flow model and Spider biofilm repressed || 1 -1.08 -1.31 -1.79 -0.98 -2.41 -2.79 -0.21 0.67 -0.46 0.86 0.50 -0.66 -0.50 -0.42 -0.87 -0.96
11709 || orf19.6343 || FEN1 || || Putative fatty acid elongase; predicted role in sphingolipid biosynthesis; possibly an essential gene, disruptants not obtained by UAU1 method; Spider and flow model biofilm induced || 1 -1.48 -1.35 -1.31 -0.20 -3.03 -3.79 -0.20 -0.07 -1.09 0.47 -0.37 -1.05 -0.23 -0.53 -1.50 -1.02
11710 || orf19.4831 || MTS1 || || Sphingolipid C9-methyltransferase; catalyzes methylation of the 9th carbon in the long chain base component of glucosylceramides; glucosylceramide biosynthesis is important for virulence; Spider biofilm repressed || 1 -1.28 -1.25 -1.47 -0.84 -2.58 -3.27 0.00 0.28 -0.76 0.15 -0.15 -0.97 -0.65 -0.33 -1.23 -0.80
11711 || orf19.3799 || || || Ortholog(s) have role in endoplasmic reticulum tubular network maintenance, nuclear pore complex assembly and Golgi apparatus, cortical endoplasmic reticulum, integral to endoplasmic reticulum membrane, mitochondrion localization || 1 -0.93 -0.94 -1.07 -0.19 -1.88 -2.31 0.20 0.20 -0.00 0.25 -0.61 -0.69 -0.36 -0.62 -0.48 -0.77
11712 || orf19.3799 || || || Ortholog(s) have role in endoplasmic reticulum tubular network maintenance, nuclear pore complex assembly and Golgi apparatus, cortical endoplasmic reticulum, integral to endoplasmic reticulum membrane, mitochondrion localization || 1 -1.02 -1.16 -0.92 -0.14 -2.15 -2.21 0.16 0.16 0.01 0.18 -0.69 -0.64 -0.54 -0.61 -0.73 -0.68
11713 || orf19.2706 || CRH11 || || GPI-anchored cell wall transglycosylase, putative ortholog of S. cerevisiae Crh1p; predicted glycosyl hydrolase domain; similar to Csf4p and to antigenic A. fumigatus Aspf9; predicted Kex2p substrate; caspofungin-induced || 1 -1.93 -2.08 -1.70 -1.13 -5.01 -4.34 0.51 0.56 0.31 0.98 -1.15 -1.51 -0.59 -0.18 -1.45 -1.34
11714 || orf19.5654 || STE24 || || Prenyl-dependent protease || 1 -0.55 -0.81 -0.72 -0.56 -1.24 -1.56 0.11 0.33 -0.14 0.16 -0.14 -0.56 -0.74 -0.12 -0.54 -0.66
11715 || orf19.5654 || STE24 || || Prenyl-dependent protease || 1 -0.88 -0.95 -0.62 -0.41 -1.67 -1.77 -0.21 0.13 -0.31 0.12 -0.14 -0.64 -0.96 -0.32 -0.88 -0.82
11716 || orf19.2150 || || || Putative ortholog of mammalian electron transfer flavoprotein complex subunit ETF-alpha; Spider biofilm repressed || 1 -0.52 -0.60 -0.64 -0.29 -1.13 -1.15 -0.05 0.24 -0.07 0.13 -0.04 -0.35 -0.76 -0.25 -1.02 -0.40
11717 || orf19.3955 || MES1 || || Cytoplasmic methionyl-tRNA synthetase; zinc-binding motif; ribosomal subunits, translation factors, tRNA synthetases are downregulated upon phagocytosis by murine macrophage; protein present in exponential and stationary phase yeast || 1 -0.73 -0.84 -0.49 -0.69 -1.72 -1.73 0.10 0.45 0.33 0.16 0.06 -0.18 -0.93 -0.01 -1.36 -0.09
11718 || orf19.5564 || || || Ortholog(s) have nucleolus localization || 1 -1.01 -1.16 -1.42 -1.00 -2.68 -2.83 0.43 0.90 0.20 0.60 0.40 -0.36 -0.39 -0.13 -1.98 -0.35
11719 || orf19.5591 || ADO1 || || Adenosine kinase; heterozygous null mutant is resistant to cordycepin in C. albicans fitness test; ketoconazole-induced; protein level decrease in stationary phase cultures; sumoylation target; Spider biofilm repressed || 1 -1.63 -1.68 -1.59 -1.02 -3.11 -3.13 0.58 0.45 -0.33 -0.10 -0.43 -0.80 -0.63 0.12 -2.24 -0.04
11720 || orf19.5591 || ADO1 || || Adenosine kinase; heterozygous null mutant is resistant to cordycepin in C. albicans fitness test; ketoconazole-induced; protein level decrease in stationary phase cultures; sumoylation target; Spider biofilm repressed || 1 -1.65 -1.76 -1.52 -1.02 -3.39 -3.19 0.63 0.34 -0.53 -0.42 -0.21 -1.05 -0.71 -0.10 -2.28 0.00
11721 || orf19.7015 || RPP0 || || Putative ribosomal protein; antigenic in mouse; repressed upon phagocytosis by murine macrophage; induced by Tbf1; overlaps orf19.7014; Spider biofilm repressed || 1 -2.44 -2.46 -3.39 0.18 0.29 -0.14 0.14 -0.35 -0.96 -0.60 -1.19 -0.06
11722 || orf19.6906 || ASC1 || || 40S ribosomal subunit similar to G-beta subunits; glucose or N starvation induced filamentation; required for virulence in mice; snoRNA snR24 encoded in ASC1 intron; repressed in stationary phase; GlcNAc-induced; Spider biofilm repressed || 1 -2.24 -2.37 -1.07 -3.50 -4.00 0.11 0.43 -0.17 0.13 0.10 -0.06 -0.95 -0.61 -1.82 -0.51
11723 || orf19.4831 || MTS1 || || Sphingolipid C9-methyltransferase; catalyzes methylation of the 9th carbon in the long chain base component of glucosylceramides; glucosylceramide biosynthesis is important for virulence; Spider biofilm repressed || 1 -1.37 -1.18 -0.93 -0.62 -2.42 -2.96 0.19 0.62 -0.24 0.53 0.07 -0.34 -0.57 0.06 -0.94 -0.27
11724 || orf19.3010 || || || Putative lipoyl ligase; role in modification of mitochondrial enzymes by attachment of lipoic acid groups; rat catheter biofilm induced || 1 -0.63 -0.61 -0.62 -0.17 -1.17 -1.41 0.32 0.20 0.16 0.32 0.05 0.01 -0.30 -0.30 -0.38 0.00
11725 || orf19.3010 || || || Putative lipoyl ligase; role in modification of mitochondrial enzymes by attachment of lipoic acid groups; rat catheter biofilm induced || 1 -0.46 -0.70 -0.44 -0.34 -1.58 -1.50 0.27 0.47 -0.09 0.25 0.23 0.06 -0.33 -0.12 -0.44 0.10
11726 || orf19.586 || ERV46 || || Putative ER-derived vesicle protein; COPII-coated vesicle complex subunit; transcript induced by filamentous growth; Spider biofilm repressed || 1 -0.53 -0.63 -0.52 -0.28 -1.71 -1.47 0.03 0.26 -0.30 0.24 0.14 0.10 -0.53 -0.16 -0.62 0.25
11727 || orf19.231 || APL2 || || Phosphorylated protein of unknown function; mutation confers hypersensitivity to toxic ergosterol analog || 1 -0.68 -0.81 -0.59 -0.34 -1.43 -1.50 0.11 0.35 -0.24 0.30 0.31 0.30 -0.45 0.07 -0.44 0.47
11728 || orf19.412 || SSH1 || || Protein with a role in protein translocation across membranes || 1 -1.14 -0.97 -1.22 -1.18 -1.02 -2.16 -0.33 -0.14 -0.50 0.10 0.07 -0.14 -0.47 -0.08 -0.68 -0.14
11729 || orf19.1860.1 || || || Ortholog(s) have extracellular region localization || 1 -0.76 -0.85 -1.51 -1.06 -1.29 -1.77 0.20 0.30 -0.32 0.11 0.55 0.22 -0.69 -0.02 -1.00 0.49
11730 || orf19.7491 || RTT109 || || Histone acetyltransferase, mutants are sensitive to DNA damage, show decreased virulence in mice, decreased white-to-opaque switching and increased susceptibility to killing by macrophages || 1 -0.77 -0.72 -1.01 -1.06 -1.17 -1.97 0.04 0.29 0.18 -0.01 -0.02 0.07 -0.12 0.16 -0.79 0.07
11731 || orf19.412 || SSH1 || || Protein with a role in protein translocation across membranes || 1 -0.68 -0.56 -1.12 -1.03 -1.23 -1.79 0.01 0.22 -0.19 0.39 0.25 -0.05 -0.28 0.22 -0.76 -0.21
11732 || orf19.1170 || ARO7 || || Putative chorismate mutase; fungal-specific (no human or murine homolog); alkaline upregulated || 1 -1.54 -1.90 -2.05 -1.75 -2.04 -2.22 0.09 0.25 -0.37 0.45 0.52 0.41 -0.45 -0.87 0.09 -0.19
11733 || orf19.1170 || ARO7 || || Putative chorismate mutase; fungal-specific (no human or murine homolog); alkaline upregulated || 1 -1.61 -1.91 -1.83 -1.58 -2.38 -2.74 0.16 0.26 -0.42 0.37 0.30 0.30 -0.56 -0.68 -0.33 -0.53
11734 || orf19.1036 || MNS1 || || Alpha-1,2-mannosidase; processes Man9GlcNAc2 to Man8GlcNAc2 isomer B; member of ER localized glycosyl hydrolase family 47; ER form is converted by Kex2 to cytosolic form; flow model biofilm repressed || 1 -1.59 -1.77 -1.04 -1.18 -1.49 -1.44 0.01 0.39 -0.02 0.49 0.21 0.02 -0.48 0.04 -0.44 -0.66
11735 || orf19.5834 || || || Ortholog(s) have protein transporter activity, role in mRNA export from nucleus and cytoplasm, nucleus localization || 1 -1.09 -1.22 -1.24 -1.13 -1.33 -1.58 0.04 0.35 -0.17 0.51 0.06 -0.05 -0.24 0.11 -0.57 -0.48
11736 || orf19.4669 || AAT22 || || Aspartate aminotransferase; nitrogen metabolism; similar but not orthologous to S. cerevisiae Aat2; clade-associated gene expression; protein levels decrease in stationary phase yeast; mutant is viable; flow model biofilm repressed || 1 -3.05 -3.51 -3.59 -2.68 -2.59 -3.70 0.31 0.70 -0.50 -0.17 0.08 -0.26 -0.79 0.19 -0.79 -1.00
11737 || orf19.2407 || DPS1-1 || || Putative tRNA-Asp synthetase; genes encoding ribosomal subunits, translation factors, tRNA synthetases are downregulated upon phagocytosis by murine macrophage; protein enriched in stationary phase yeast cultures || 1 -1.57 -1.47 -1.81 -1.36 -1.03 -1.25 0.10 0.10 -0.28 0.03 0.20 -0.11 -1.01 -0.34 -0.22 -0.29
11738 || orf19.6565 || || || Conserved mitochondrial inner membrane insertase; mediates insertion of mitochondrial- and nuclear-encoded proteins from the matrix into the inner membrane; Spider biofilm repressed || 1 -2.18 -2.32 -2.63 -2.18 -1.70 -2.12 0.01 0.21 -0.07 0.50 -0.04 -0.18 -1.18 -0.79 -0.96 -0.19
11739 || orf19.6524 || TOM40 || || Protein involved in mitochondrial protein import; Spider biofilm repressed || 1 -1.51 -1.65 -2.28 -1.89 -1.57 -1.88 0.27 0.35 -0.07 0.06 0.41 -0.05 -1.04 -0.54 -0.86 -0.45
11740 || orf19.3240 || ERG27 || || 3-Keto sterol reductase of ergosterol biosynthesis; acts in C-4 sterol demethylation with Erg25p and Erg26p; possible drug target, essential for viability; functional homolog of S. cerevisiae Erg27p || 1 -0.94 -1.05 -1.41 -0.98 -1.05 -1.65 -0.09 0.32 -0.17 0.04 -0.05 -0.22 -0.65 -0.04 -0.69 -0.05
11741 || orf19.3324 || TIF || || Translation initiation factor; upregulated in highly virulent strain compared to less virulent strain; antigenic in human; flucytosine induced; downregulated upon phagocytosis by macrophages; Spider biofilm repressed || 1 -1.31 -1.35 -1.60 -1.25 -1.35 -1.80 0.01 0.13 -0.19 0.03 0.19 -0.03 -0.75 -0.23 -0.85 0.03
11742 || orf19.3324 || TIF || || Translation initiation factor; upregulated in highly virulent strain compared to less virulent strain; antigenic in human; flucytosine induced; downregulated upon phagocytosis by macrophages; Spider biofilm repressed || 1 -1.28 -1.48 -1.60 -1.37 -1.32 -1.82 -0.02 -0.04 -0.32 0.08 0.09 -0.12 -0.89 -0.31 -0.68 0.01
11743 || orf19.3324 || TIF || || Translation initiation factor; upregulated in highly virulent strain compared to less virulent strain; antigenic in human; flucytosine induced; downregulated upon phagocytosis by macrophages; Spider biofilm repressed || 1 -1.49 -1.54 -1.71 -1.51 -1.59 -2.08 0.13 0.01 -0.53 0.06 0.05 -0.23 -0.89 -0.47 -1.02 0.00
11744 || orf19.1637 || || || Ortholog(s) have cytosol, nucleus localization || 1 -0.83 -0.90 -1.26 -1.23 -0.86 -1.34 -0.11 -0.06 -0.17 -0.01 -0.02 -0.11 -0.58 -0.14 -0.32 0.19
11745 || orf19.1637 || || || Ortholog(s) have cytosol, nucleus localization || 1 -0.92 -0.91 -1.03 -1.19 -0.94 -1.46 -0.23 -0.27 -0.18 -0.14 0.04 -0.19 -0.64 -0.35 -0.29 -0.07
11746 || orf19.3324 || TIF || || Translation initiation factor; upregulated in highly virulent strain compared to less virulent strain; antigenic in human; flucytosine induced; downregulated upon phagocytosis by macrophages; Spider biofilm repressed || 1 -1.52 -1.71 -2.38 -1.77 -1.76 -2.40 0.03 -0.17 -0.90 0.06 -0.19 -0.87 -1.01 -0.81 -1.04 -0.22
11747 || orf19.4932 || || || Ortholog(s) have role in mitochondrial translation and mitochondrion localization || 1 -1.25 -1.35 -1.78 -1.71 -1.70 -1.62 0.04 0.10 0.09 0.43 -0.34 -0.54 -0.77 -0.56 -0.65 -0.36
11748 || orf19.4932 || || || Ortholog(s) have role in mitochondrial translation and mitochondrion localization || 1 -1.46 -1.46 -1.70 -1.53 -1.65 -1.39 0.11 0.33 0.16 0.66 -0.22 -0.22 -1.16 -0.63 -0.56 -0.27
11749 || orf19.4932 || || || Ortholog(s) have role in mitochondrial translation and mitochondrion localization || 1 -1.45 -1.54 -2.32 -1.90 -1.47 -1.40 0.06 0.24 0.29 0.65 -0.13 -0.15 -0.98 -0.19 -0.35 -0.47
11750 || orf19.5563 || RNH1 || || Ribonuclease H (RNAse H); hyphal-induced; flucytosine induced; similar to orf19.5564 (see Locus History); possibly essential (UAU1 method); rat catheter biofilm induced; flow model biofilm repressed || 1 -0.99 -0.94 -1.54 -1.06 -1.39 -1.60 0.26 0.61 -0.32 0.66 0.15 -0.14 -0.74 0.12 -0.43 -0.46
11751 || orf19.2967 || TIF34 || || Putative translation initiation factor eIF3, p39 subunit; mutation confers hypersensitivity to roridin A, verrucarin A; downregulated upon phagocytosis by murine macrophages; Spider biofilm repressed || 1 -0.99 -1.06 -1.73 -1.30 -1.12 -1.47 -0.01 0.75 -0.58 0.51 0.46 -0.06 -0.49 0.14 -0.57 0.00
11752 || orf19.269 || SES1 || || Seryl-tRNA synthetase; charges the tRNA that recognizes the CUG codon, which typically specifies Leu, but specifies Ser in C. albicans; complements S. cerevisiae ses1 mutant viability; soluble protein in hyphae; macrophage-regulated || 1 -1.58 -1.61 -2.29 -1.88 -1.85 -2.23 0.03 0.47 -0.83 0.37 0.31 -0.39 -0.93 -0.02 -1.30 -0.42
11753 || orf19.4517 || || || Protein of unknown function; Hap43-induced gene || 1 -1.87 -1.60 -2.71 -1.84 -2.04 -2.34 -0.40 0.46 -0.99 0.71 0.36 -0.43 -0.47 0.23 -0.77 -0.30
11754 || orf19.6438 || || || Ortholog(s) have serine C-palmitoyltransferase activity, role in sphingolipid biosynthetic process and SPOTS complex localization || 1 -0.89 -1.00 -1.48 -1.04 -1.12 -1.84 -0.19 0.25 -0.74 0.35 0.13 -0.23 -0.61 0.09 -0.57 0.01
11755 || orf19.4036 || APM1 || || Ortholog of S. cerevisiae/S. pombe Apm1; a clathrin-associated protein complex (AP-1) subunit; phosphorylated protein; Tn mutation affects filamentous growth; Spider biofilm repressed || 1 -0.76 -0.97 -1.03 -1.04 -0.86 -1.28 -0.29 0.23 -0.47 0.32 0.23 0.03 -0.42 -0.05 -0.07 -0.30
11756 || orf19.1672 || || || Alpha subunit of COPI vesicle coatomer complex; role in ER to Golgi vesicle-mediated transport, retrograde vesicle-mediated transport, Golgi to ER transport; flow model biofilm repressed || 1 -0.58 -0.59 -0.75 -0.37 -0.87 -1.06 -0.08 -0.13 -0.44 -0.05 0.05 0.04 -0.25 -0.18 -0.23 0.00
11757 || orf19.1765 || || || Secreted protein; fluconazole-induced || 1 -0.89 -1.25 -1.68 -1.16 -2.03 -1.95 -0.25 -0.12 -0.32 -0.42 -0.05 -0.32 -0.56 -0.43 -0.25 0.08
11758 || orf19.6810 || || || Ortholog(s) have protein serine/threonine phosphatase activity || 1 -0.80 -0.94 -1.30 -1.09 -1.41 -1.50 -0.32 -0.17 -0.29 -0.40 -0.02 -0.28 -0.54 -0.14 -0.72 -0.08
11759 || orf19.7100 || || || Putative vacuolar transporter of large neutral amino acids; possibly transcriptionally regulated upon hyphal formation; not the true Avt1 ortholog of S. cerevisiae || 1 -1.25 -1.34 -1.30 -1.05 -1.54 -1.59 -0.47 -0.07 -0.39 -0.21 0.39 0.38 -0.59 -0.05 -1.04 -0.03
11760 || orf19.1683 || PPH21 || || Putative protein phosphatase of the Type 2A-related family (serine/threonine-specific), similar to S. cerevisiae Pph21p; caspofungin repressed; possibly an essential gene, disruptants not obtained by UAU1 method || 1 -0.98 -1.07 -1.01 -1.01 -1.73 -1.64 -0.32 -0.03 -0.50 -0.32 0.04 -0.00 -0.72 -0.32 -0.91 -0.53
11761 || orf19.5689 || || || Epsilon-COP subunit of the coatomer; regulates retrograde Golgi-to-ER protein traffic; Spider biofilm repressed || 1 -0.56 -0.63 -0.68 -0.77 -0.97 -1.00 -0.16 0.16 -0.32 -0.16 0.14 -0.14 -0.53 -0.16 -0.45 0.01
11762 || orf19.5647 || SUB2 || || Putative TREX complex component with a predicted role in nuclear mRNA export; transcription is regulated by Mig1; Hap43-induced gene; Spider biofilm repressed || 1 -0.99 -1.01 -0.97 -0.85 -1.24 -1.33 -0.07 0.23 -0.53 -0.19 0.31 0.06 -0.69 -0.20 -0.46 -0.05
11763 || orf19.2276 || || || Ortholog(s) have DNA-directed RNA polymerase activity, RNA-directed RNA polymerase activity || 1 -1.40 -1.62 -1.50 -1.23 -2.35 -2.22 -0.28 0.16 -0.45 -0.28 0.22 0.01 -0.84 -0.12 -0.83 -0.19
11764 || orf19.1782 || || || Membrane-localized protein of unknown function || 1 -1.54 -1.65 -1.33 -0.97 -1.67 -2.05 -0.12 0.31 -0.19 -0.22 0.27 -0.06 -0.67 -0.19 -0.61 -0.35
11765 || orf19.1372 || || || Protein of unknown function; transcript regulated by Mig1 and Tup1 || 1 -1.65 -1.67 -1.46 -1.18 -2.16 -2.27 -0.29 0.06 -0.51 -0.08 0.15 -0.19 -0.84 -0.11 -1.06 -0.47
11766 || orf19.1782 || || || Membrane-localized protein of unknown function || 1 -1.75 -1.68 -1.29 -1.21 -1.76 -2.07 -0.32 0.09 -0.37 0.01 0.03 -0.27 -0.61 -0.08 -0.95 -0.67
11767 || orf19.1806 || || || Ortholog of C. dubliniensis CD36 : Cd36_30340, C. parapsilosis CDC317 : CPAR2_203900, Candida tenuis NRRL Y-1498 : CANTEDRAFT_113094 and Debaryomyces hansenii CBS767 : DEHA2G22374g || 1 -1.63 -1.97 -1.55 -1.20 -2.06 -2.32 -0.30 -0.13 -0.34 -0.11 -0.22 0.38 -0.23 0.02 -1.06 -0.37
11768 || orf19.1806 || || || Ortholog of C. dubliniensis CD36 : Cd36_30340, C. parapsilosis CDC317 : CPAR2_203900, Candida tenuis NRRL Y-1498 : CANTEDRAFT_113094 and Debaryomyces hansenii CBS767 : DEHA2G22374g || 1 -1.70 -1.90 -1.60 -1.18 -1.95 -1.94 -0.13 -0.06 -0.62 -0.15 -0.07 -0.00 -0.15 -0.09 -0.44 -0.12
11769 || orf19.1690 || TOS1 || || Protein similar to alpha agglutinin anchor subunit; secreted; exogenously expressed protein is a substrate for Kex2 processing in vitro; fluconazole-induced; induced by alpha pheromone in SpiderM medium; Hap43-induced || 1 -1.46 -1.73 -1.42 -0.94 -1.97 -1.99 -0.40 -0.05 -0.41 0.10 0.41 -0.29 -0.39 -0.83 -1.02 -0.19
11770 || orf19.1661 || DBP5 || || Ortholog(s) have RNA helicase activity, RNA-dependent ATPase activity, inositol hexakisphosphate binding activity and role in mRNA export from nucleus, translational termination || 1 -0.77 -0.61 -0.73 -0.81 -0.72 -0.93 -0.18 0.03 -0.34 0.09 -0.23 -0.17 -0.50 0.03 -0.62 -0.15
11771 || orf19.7243 || || || Deoxycytidine monophosphate (dCMP) deaminase; role in dUMP and dTMP biosynthesis; Spider biofilm repressed || 1 -0.92 -1.21 -0.93 -0.65 -1.13 -1.29 0.01 0.36 -0.16 0.33 0.24 -0.40 -0.90 0.11 -0.87 -0.19
11772 || orf19.2960 || FRS2 || || Putative tRNA-Phe synthetase; downregulated upon phagocytosis by murine macrophage; protein present in exponential and stationary growth phase yeast cultures; Spider biofilm repressed || 1 -1.58 -1.37 -1.24 -0.78 -1.63 -1.37 -0.12 0.32 -0.29 0.35 -0.13 -0.35 -1.24 -0.14 -1.11 -0.17
11773 || orf19.3955 || MES1 || || Cytoplasmic methionyl-tRNA synthetase; zinc-binding motif; ribosomal subunits, translation factors, tRNA synthetases are downregulated upon phagocytosis by murine macrophage; protein present in exponential and stationary phase yeast || 1 -1.34 -1.24 -1.28 -1.29 -1.88 -1.78 -0.09 -0.12 -0.37 0.09 -0.11 -0.64 -1.17 -0.21 -1.45 -0.19
11774 || orf19.2573 || FRS1 || || Phenylalanyl-tRNA synthetase; possible role in early cell wall biosynthesis; downregulated by phagocytosis by macrophages; possibly essential gene, disruptants not obtained by UAU1 method; protein present in exponential and stationary phase || 1 -1.35 -1.14 -1.84 -1.33 -2.07 -2.12 0.12 0.38 -0.65 0.06 0.01 -0.53 -1.13 -0.05 -1.25 -0.21
11775 || orf19.4536 || CYS4 || || Cystathionine beta-synthase; sulfur amino acid biosynthesis; antigenic in mouse; flow model biofilm induced; alkaline induced; macrophage/pseudohyphal-induced; present in exponential and stationary growth phase yeast cultures || 1 -0.57 -0.56 -1.09 -0.78 -1.47 -1.21 0.15 0.22 -0.37 0.21 0.20 -0.25 -0.59 0.03 -0.86 -0.02
11776 || orf19.4809 || ERG12 || || Ortholog(s) have mevalonate kinase activity and role in ergosterol biosynthetic process, farnesyl diphosphate biosynthetic process, mevalonate pathway, isopentenyl diphosphate biosynthetic process, mevalonate pathway || 1 -1.08 -1.11 -1.40 -1.30 -1.87 -1.44 0.03 0.52 -0.38 0.56 0.48 -0.01 -0.50 0.03 -0.68 0.12
11777 || orf19.390 || CDC42 || || Rho-type GTPase; required for budding and maintenance of hyphal growth; GGTase I geranylgeranylated; misexpression blocks hyphal growth, causes avirulence in mouse IV infection; shows actin-dependent localization to hyphal tip || 1 -0.98 -0.79 -0.88 -0.83 -1.50 -1.32 -0.15 0.46 -0.06 0.48 0.36 0.25 -0.55 0.21 -0.58 -0.03
11778 || orf19.7382 || CAM1 || || Putative translation elongation factor eEF1 gamma; protein level decreased in stationary phase cultures; Spider biofilm repressed || 1 -0.76 -0.66 -0.95 -0.55 -1.40 -1.33 0.14 0.34 0.13 0.32 0.13 -0.05 -0.92 0.07 -0.86 -0.20
11779 || orf19.5685 || THS1 || || Putative threonyl-tRNA synthetase; transcript regulated by Mig1 and Tup1; repressed upon phagocytosis by murine macrophages; stationary phase enriched protein; Spider biofilm repressed || 1 -1.14 -1.16 -1.13 -0.76 -1.86 -1.76 0.34 0.61 0.01 0.52 0.42 0.16 -0.91 0.04 -1.14 -0.04
11780 || orf19.2651 || CAM1-1 || || Putative translation elongation factor; downregulated upon phagocytosis by murine macrophages; Hap43-induced gene; Spider biofilm repressed || 1 -0.55 -0.71 -0.93 -0.75 -1.48 -1.43 0.18 0.38 0.05 0.22 0.57 0.13 -0.82 -0.05 -0.78 -0.11
11781 || orf19.2651 || CAM1-1 || || Putative translation elongation factor; downregulated upon phagocytosis by murine macrophages; Hap43-induced gene; Spider biofilm repressed || 1 -0.72 -0.72 -0.95 -0.59 -1.52 -1.41 0.06 0.26 -0.14 0.12 0.49 0.08 -0.92 0.09 -0.78 0.06
11782 || orf19.6701 || || || Protein with similarity to amino acid-tRNA ligase; stationary phase enriched protein; GlcNAc-induced protein || 1 -1.17 -1.07 -0.98 -0.57 -1.91 -1.81 0.45 0.41 0.12 0.44 0.65 0.26 -0.55 0.03 -0.51 -0.11
11783 || orf19.1986 || ARO2 || || Putative chorismate synthase; fungal-specific (no human or murine homolog); protein level decreased in stationary phase yeast cultures; GlcNAc-induced protein || 1 -1.24 -1.30 -1.25 -0.96 -1.88 -2.16 0.59 0.87 0.29 0.19 0.64 0.04 -0.72 0.41 -0.93 0.05
11784 || orf19.5685 || THS1 || || Putative threonyl-tRNA synthetase; transcript regulated by Mig1 and Tup1; repressed upon phagocytosis by murine macrophages; stationary phase enriched protein; Spider biofilm repressed || 1 -1.22 -1.18 -1.34 -1.06 -1.42 -1.85 0.41 0.63 0.06 0.47 0.73 0.30 -0.88 0.31 -0.86 0.18
11785 || orf19.6701 || || || Protein with similarity to amino acid-tRNA ligase; stationary phase enriched protein; GlcNAc-induced protein || 1 -0.62 -0.80 -0.98 -0.87 -1.26 -1.66 0.40 0.50 0.06 0.41 0.56 0.30 -0.50 0.01 -0.42 0.21
11786 || orf19.3347 || RPB7 || || Functional homolog of S. cerevisiae Rpb7; essential subunit of RNA Polymerase II; enhances hyperfilamentation of an S. cerevisiae rpb4 mutant; suppresses defects of S. cerevisiae rpb4 and ess1 mutants; Spider biofilm repressed || 1 -1.31 -1.47 -0.99 -1.17 -1.67 -1.33 -0.04 0.30 0.02 0.20 0.35 0.17 -0.29 0.17 -0.58 0.10
11787 || orf19.4650 || ILV6 || || Putative regulatory subunit of acetolacetate synthase; alkaline induced; regulated by Gcn2 and Gcn4; protein present in exponential and stationary growth phase yeast; Spider biofilm repressed || 1 -2.05 -2.19 -2.42 -1.68 -2.22 -1.91 0.34 0.14 -0.00 -0.33 0.55 0.35 -0.86 0.08 -0.49 -0.01
11788 || orf19.4650 || ILV6 || || Putative regulatory subunit of acetolacetate synthase; alkaline induced; regulated by Gcn2 and Gcn4; protein present in exponential and stationary growth phase yeast; Spider biofilm repressed || 1 -1.57 -1.50 -1.84 -1.45 -1.76 -1.79 0.24 0.09 0.07 -0.25 0.53 0.24 -0.74 -0.14 -0.74 0.24
11789 || orf19.4650 || ILV6 || || Putative regulatory subunit of acetolacetate synthase; alkaline induced; regulated by Gcn2 and Gcn4; protein present in exponential and stationary growth phase yeast; Spider biofilm repressed || 1 -1.53 -1.59 -1.93 -1.71 -1.69 -1.88 0.34 0.01 0.03 -0.23 0.58 0.10 -0.67 -0.12 -0.76 0.17
11790 || orf19.7188 || RPP1B || || Conserved acidic ribosomal protein, likely involved in regulation of translation elongation; interacts with Rpp2A; 1 of 4 similar C. albicans ribosomal proteins (Rpp1A, Rpp1B, Rpp2A, Rpp2B); induced by Tbf1; Spider biofilm repressed || 1 -2.27 -2.26 -2.51 -1.75 -2.81 -3.20 0.65 0.58 -0.15 0.34 0.85 0.55 -0.78 -0.12 -0.80 0.59
11791 || orf19.7188 || RPP1B || || Conserved acidic ribosomal protein, likely involved in regulation of translation elongation; interacts with Rpp2A; 1 of 4 similar C. albicans ribosomal proteins (Rpp1A, Rpp1B, Rpp2A, Rpp2B); induced by Tbf1; Spider biofilm repressed || 1 -2.38 -2.45 -2.54 -1.74 -2.74 -3.14 0.57 0.55 -0.09 0.34 0.77 0.53 -0.86 -0.11 -0.89 0.54
11792 || orf19.7188 || RPP1B || || Conserved acidic ribosomal protein, likely involved in regulation of translation elongation; interacts with Rpp2A; 1 of 4 similar C. albicans ribosomal proteins (Rpp1A, Rpp1B, Rpp2A, Rpp2B); induced by Tbf1; Spider biofilm repressed || 1 -2.34 -2.47 -2.78 -1.90 -2.83 -3.28 0.64 0.61 -0.13 0.32 0.68 0.47 -0.89 -0.26 -0.88 0.45
11793 || orf19.7188 || RPP1B || || Conserved acidic ribosomal protein, likely involved in regulation of translation elongation; interacts with Rpp2A; 1 of 4 similar C. albicans ribosomal proteins (Rpp1A, Rpp1B, Rpp2A, Rpp2B); induced by Tbf1; Spider biofilm repressed || 1 -2.23 -2.34 -2.58 -1.95 -2.68 -3.13 0.53 0.56 -0.15 0.27 0.76 0.54 -0.91 -0.05 -0.80 0.33
11794 || orf19.7188 || RPP1B || || Conserved acidic ribosomal protein, likely involved in regulation of translation elongation; interacts with Rpp2A; 1 of 4 similar C. albicans ribosomal proteins (Rpp1A, Rpp1B, Rpp2A, Rpp2B); induced by Tbf1; Spider biofilm repressed || 1 -2.27 -2.30 -2.50 -1.77 -2.74 -3.13 0.63 0.65 -0.05 0.37 0.86 0.41 -0.77 -0.19 -1.04 0.21
11795 || orf19.7217 || RPL4B || || Ribosomal protein 4B; repressed upon phagocytosis by murine macrophage; Spider biofilm repressed || 1 -2.71 -2.71 -2.77 -2.16 -2.76 -3.14 0.56 0.50 -0.03 0.39 0.64 0.29 -0.80 -0.19 -0.94 0.56
11796 || orf19.6367 || SSB1 || || HSP70 family heat shock protein; mRNA in yeast and germ tubes; at yeast cell surface, not hyphae; antigenic in human/mouse infection; macrophage, GCN-induced; possibly essential; sumoylation target; Hap43-induced; Spider biofilm repressed || 1 -1.47 -1.67 -1.44 -1.73 -2.05 0.49 0.45 0.03 0.36 -0.10 -0.67 -0.29 -0.92 0.14
11797 || orf19.1598 || ERG24 || || C-14 sterol reductase, has a role in ergosterol biosynthesis; mutation confers increased sensitivity to dyclonine; rat catheter and Spider biofilm repressed || 1 -2.05 -2.07 -2.03 -1.48 -2.23 -2.79 0.54 0.72 0.19 0.25 0.62 -0.09 -0.61 0.19 -1.40 -0.05
11798 || orf19.6702 || DED81 || || Putative tRNA-Asn synthetase; genes encoding ribosomal subunits, translation factors, tRNA synthetases are downregulated upon phagocytosis by murine macrophage; protein enriched in stationary phase yeast cultures || 1 -1.35 -1.45 -1.86 -1.59 -2.28 -2.42 0.32 0.33 -0.32 0.12 0.39 -0.26 -0.93 -0.13 -1.01 0.25
11799 || orf19.5685 || THS1 || || Putative threonyl-tRNA synthetase; transcript regulated by Mig1 and Tup1; repressed upon phagocytosis by murine macrophages; stationary phase enriched protein; Spider biofilm repressed || 1 -1.35 -1.23 -1.29 -1.19 -1.89 -1.94 0.27 0.38 -0.13 0.27 0.27 -0.03 -1.01 -0.06 -1.36 0.17
11800 || orf19.6906 || ASC1 || || 40S ribosomal subunit similar to G-beta subunits; glucose or N starvation induced filamentation; required for virulence in mice; snoRNA snR24 encoded in ASC1 intron; repressed in stationary phase; GlcNAc-induced; Spider biofilm repressed || 1 -2.12 -2.51 -2.34 -1.56 -3.21 -3.47 0.27 0.52 0.00 0.42 0.48 -0.13 -1.13 -0.22 -1.91 -0.04
11801 || orf19.3240 || ERG27 || || 3-Keto sterol reductase of ergosterol biosynthesis; acts in C-4 sterol demethylation with Erg25p and Erg26p; possible drug target, essential for viability; functional homolog of S. cerevisiae Erg27p || 1 -1.27 -1.50 -1.78 -1.24 -1.61 -1.86 0.09 0.43 -0.03 0.16 0.34 -0.24 -0.83 0.19 -1.02 -0.23
11802 || orf19.198 || ASN1 || || Putative asparagine synthetase; soluble protein in hyphae; regulated by Rim101; decreased expression at pH 4 vs pH 8; protein detected during exponential and stationary phases of yeast-form growth || 1 -2.58 -2.36 -2.34 -1.85 -2.86 -2.87 0.65 0.46 0.62 0.02 0.25 0.09 -1.12 0.16 -1.21 -0.06
11803 || orf19.198 || ASN1 || || Putative asparagine synthetase; soluble protein in hyphae; regulated by Rim101; decreased expression at pH 4 vs pH 8; protein detected during exponential and stationary phases of yeast-form growth || 1 -1.79 -1.93 -2.39 -1.73 -2.82 -2.85 0.75 0.38 0.67 -0.02 0.39 0.07 -0.97 0.17 -1.16 0.06
11804 || orf19.5870 || CTP1 || || Putative citrate transport protein; flucytosine induced; amphotericin B repressed, caspofungin repressed; Hap43p-induced gene || 1 -1.98 -2.07 -2.13 -2.02 -2.52 -2.91 0.56 0.29 0.73 -0.42 0.04 -0.22 -0.95 -0.27 -1.69 0.05
11805 || orf19.3590 || IPP1 || || Putative inorganic pyrophosphatase; antigenic; soluble protein in hyphae; macrophage-induced protein; protein present in exponential and stationary phase yeast; possibly essential (UAU1 method); sumoylation target; Spider biofilm repressed || 1 -0.60 -0.63 -0.72 -0.58 -0.95 -1.10 0.33 0.29 -0.07 0.01 0.33 -0.03 -0.24 -0.10 -0.61 -0.14
11806 || orf19.7312 || ERG13 || || 3-hydroxy-3-methylglutaryl coenzyme A synthase; ergosterol biosynthesis; sumoylation target; Tn mutation affects filamentation; amphotericin B, caspofungin repressed; exponential, stationary growth phase expressed; Spider biofilm repressed || 1 -2.09 -2.45 -2.18 -1.88 -3.89 -3.62 0.44 0.73 0.06 0.38 0.69 -0.42 -0.35 0.48 -2.75 0.03
11807 || orf19.7312 || ERG13 || || 3-hydroxy-3-methylglutaryl coenzyme A synthase; ergosterol biosynthesis; sumoylation target; Tn mutation affects filamentation; amphotericin B, caspofungin repressed; exponential, stationary growth phase expressed; Spider biofilm repressed || 1 -2.43 -2.56 -3.06 -2.42 -4.01 -4.09 0.45 0.64 -0.30 -0.12 0.44 -0.45 -0.33 0.24 -2.09 -0.18
11808 || orf19.3616 || ERG9 || || Putative farnesyl-diphosphate farnesyl transferase (squalene synthase); sterol biosynthesis pathway; likely essential for growth; regulated by fluconazole, lovastatin; amphotericin B, caspofungin repressed; Spider biofilm repressed || 1 -1.18 -1.33 -1.36 -1.36 -2.30 -1.86 0.18 0.34 -0.11 -0.32 0.44 -0.14 -0.15 0.36 -1.21 0.42
11809 || orf19.156 || FGR51 || || Protein lacking an ortholog in S. cerevisiae; transposon mutation affects filamentous growth; Hap43p-repressed gene || 1 -1.18 -1.01 -1.16 -0.81 -1.20 -1.62 0.14 0.30 -0.13 -0.29 -0.09 -0.39 -0.50 -0.14 -1.19 -0.33
11810 || orf19.922 || ERG11 || || Lanosterol 14-alpha-demethylase; cytochrome P450 family; role in ergosterol biosynthesis; target of azole antifungals; may contribute to drug resistance; azole or flow model biofilm induced; drug treated biofilm induced; hypoxia regulated || 1 -2.06 -1.88 -2.57 -2.34 -2.14 -2.06 0.25 0.20 -0.07 -0.51 0.28 -0.18 -0.93 -0.65 -2.14 0.05
11811 || orf19.5178 || ERG5 || || Putative C-22 sterol desaturase; fungal C-22 sterol desaturases are cytochrome P450 enzymes of ergosterol biosynthesis, catalyze formation of the C-22(23) double bond in the sterol side chain; transposon mutation affects filamentous growth || 1 -1.62 -1.69 -2.05 -1.89 -2.23 -1.77 -0.42 -0.20 -0.55 -0.50 -0.13 -0.66 -0.38 -0.60 -1.84 -0.25
11812 || orf19.7186 || CLB4 || || B-type mitotic cyclin; nonessential; negative regulator of pseudohyphal growth; dispensible for mitotic exit, cytokinesis; Fkh2-represed; flow model biofilm repressed; farnesol-upregulated in biofilm; reduced total RNA in clb4 mutant || 1 -1.04 -1.22 -1.24 -1.07 -2.04 -2.18 -0.01 0.35 -0.49 -0.26 0.34 0.27 -0.17 0.47 -1.48 0.17
11813 || orf19.6936 || RAD53 || || Protein involved in regulation of DNA-damage-induced filamentous growth; putative component of cell cycle checkpoint; ortholog of S. cerevisiae Rad53p, protein kinase required for cell-cycle arrest in response to DNA damage || 1 -0.98 -1.08 -0.85 -0.76 -1.58 -2.06 -0.21 0.23 -0.39 0.08 0.37 0.08 -0.28 0.17 -1.06 0.35
11814 || orf19.7186 || CLB4 || || B-type mitotic cyclin; nonessential; negative regulator of pseudohyphal growth; dispensible for mitotic exit, cytokinesis; Fkh2-represed; flow model biofilm repressed; farnesol-upregulated in biofilm; reduced total RNA in clb4 mutant || 1 -1.30 -1.14 -0.70 -0.71 -1.84 -2.04 -0.24 0.15 -0.52 -0.25 0.05 -0.02 -0.23 0.01 -1.47 0.15
11815 || orf19.7538 || || || DNA helicase involved in rDNA replication; Spider biofilm repressed || 1 -1.21 -1.17 -1.01 -0.83 -1.82 -2.07 -0.09 0.20 -0.33 -0.22 0.09 0.05 -0.89 0.03 -1.53 0.08
11816 || orf19.759 || SEC21 || || Ortholog(s) have role in ER to Golgi vesicle-mediated transport, retrograde vesicle-mediated transport, Golgi to ER and COPI vesicle coat, cytosol, endosome localization || 1 -0.83 -0.80 -0.59 -0.39 -1.09 -1.21 -0.10 0.17 -0.38 0.05 0.18 0.13 -0.56 0.29 -0.59 0.28
11817 || orf19.4109 || PMT4 || || Protein mannosyltransferase; required for WT cell wall composition and virulence in mice; roles in hyphal growth and drug sensitivity; one of 5 family members; Axl2 a substrate; Spider biofilm repressed; Bcr1-repressed in RPMI a/a biofilm || 1 -1.33 -1.12 -0.74 -0.76 -1.76 -1.68 -0.09 0.34 -0.40 0.19 0.29 0.29 -0.82 0.11 -0.92 0.26
11818 || orf19.5647 || SUB2 || || Putative TREX complex component with a predicted role in nuclear mRNA export; transcription is regulated by Mig1; Hap43-induced gene; Spider biofilm repressed || 1 -0.79 -0.93 -0.69 -0.69 -1.35 -1.10 -0.07 0.24 -0.43 0.09 0.17 0.27 -0.81 0.09 -0.68 0.35
11819 || orf19.4536 || CYS4 || || Cystathionine beta-synthase; sulfur amino acid biosynthesis; antigenic in mouse; flow model biofilm induced; alkaline induced; macrophage/pseudohyphal-induced; present in exponential and stationary growth phase yeast cultures || 1 -0.69 -0.78 -0.96 -0.82 -1.53 -1.15 -0.05 0.07 -0.43 0.19 0.15 0.04 -0.83 0.17 -0.61 0.25
11820 || orf19.5689 || || || Epsilon-COP subunit of the coatomer; regulates retrograde Golgi-to-ER protein traffic; Spider biofilm repressed || 1 -0.59 -0.67 -0.56 -0.37 -1.14 -0.96 -0.23 0.02 -0.23 -0.11 -0.06 -0.04 -0.82 0.02 -0.56 0.19
11821 || orf19.2951 || HOM6 || || Putative homoserine dehydrogenase; Gcn4-regulated; induced by amino acid starvation (3-ATtreatment); macrophage-induced protein; protein level decreases in stationary phase cultures; flow model biofilm repressed || 1 -1.60 -1.52 -1.28 -1.17 -2.12 -2.04 0.38 0.20 0.02 -0.25 -0.53 -0.22 -1.24 -0.15 -1.15 -0.33
11822 || orf19.2951 || HOM6 || || Putative homoserine dehydrogenase; Gcn4-regulated; induced by amino acid starvation (3-ATtreatment); macrophage-induced protein; protein level decreases in stationary phase cultures; flow model biofilm repressed || 1 -1.20 -1.22 -1.04 -0.64 -1.91 -1.60 0.53 0.29 0.43 -0.01 -0.21 -0.01 -0.84 0.31 -0.71 -0.33
11823 || orf19.4718 || TRP5 || || Predicted tryptophan synthase; identified in detergent-resistant membrane fraction (possible lipid raft component); predicted N-terminal acetylation; Gcn4p-regulated; S. cerevisiae ortholog is Gcn4p regulated; upregulated in biofilm; || 1 -1.26 -0.84 -1.47 -1.44 -1.39 -2.22 0.69 0.08 0.28 -0.28 0.21 -0.20 -0.99 -0.30 -0.87 -0.11
11824 || orf19.390 || CDC42 || || Rho-type GTPase; required for budding and maintenance of hyphal growth; GGTase I geranylgeranylated; misexpression blocks hyphal growth, causes avirulence in mouse IV infection; shows actin-dependent localization to hyphal tip || 1 -0.47 -0.72 -0.62 -0.53 -1.32 -1.20 -0.19 0.38 0.06 0.56 0.40 0.32 -0.48 0.36 -0.39 -0.20
11825 || orf19.587 || || || Ortholog(s) have transcription export complex localization || 1 -0.91 -1.00 -0.49 -0.66 -1.46 -1.69 -0.07 0.16 0.06 0.41 0.29 0.31 -0.77 0.61 -0.60 0.05
11826 || orf19.2641 || ARP1 || || Putative centractin; induced upon adherence to polystyrene || 1 -0.54 -0.79 -1.01 -0.35 -1.17 -1.90 0.07 0.24 -0.02 0.70 0.31 0.09 -0.60 0.34 -0.90 0.10
11827 || orf19.2775 || IDI1 || || Ortholog(s) have isopentenyl-diphosphate delta-isomerase activity, role in farnesyl diphosphate biosynthetic process and cytosol, nucleus localization || 1 -0.76 -0.76 -1.15 -0.54 -1.75 -2.11 0.19 0.49 -0.38 0.63 0.61 0.03 -0.53 0.43 -0.84 -0.00
11828 || orf19.6247 || || || Ortholog(s) have chromatin binding activity || 1 -1.21 -1.35 -1.52 -0.78 -2.12 -2.51 -0.45 0.17 -0.69 0.62 0.79 -0.03 -1.02 0.28 -1.63 -0.10
11829 || orf19.4030 || || || Ortholog(s) have DNA primase activity, single-stranded DNA binding activity, role in DNA replication, synthesis of RNA primer, telomere maintenance and alpha DNA polymerase:primase complex localization || 1 -0.86 -0.90 -1.09 -0.83 -1.09 -2.01 -0.19 0.59 -0.53 0.59 1.09 0.10 -0.58 0.41 -1.01 0.36
11830 || orf19.4030 || || || Ortholog(s) have DNA primase activity, single-stranded DNA binding activity, role in DNA replication, synthesis of RNA primer, telomere maintenance and alpha DNA polymerase:primase complex localization || 1 -1.11 -1.00 -0.82 -0.77 -1.28 -1.68 0.05 0.83 -0.32 0.68 1.00 -0.06 -0.84 0.57 -0.79 0.26
11831 || orf19.3211 || RCF3 || || Putative heteropentameric replication factor C subunit; transcription is induced upon filamentous growth || 1 -0.73 -0.72 -1.11 -0.78 -1.01 -2.04 -0.24 0.53 -0.67 0.45 0.44 0.01 -0.81 -0.16 -1.22 -0.25
11832 || orf19.2029 || RFC5 || || Putative heteropentameric replication factor C subunit; periodic mRNA expression, peak at cell-cycle G1/S phase || 1 -0.58 -0.45 -1.05 -0.49 -1.02 -2.32 -0.16 0.41 -0.88 0.31 0.89 -0.19 -0.96 -0.16 -0.82 0.40
11833 || orf19.2029 || RFC5 || || Putative heteropentameric replication factor C subunit; periodic mRNA expression, peak at cell-cycle G1/S phase || 1 -0.55 -0.64 -2.24 -0.17 -1.33 -2.76 0.05 0.76 -0.71 0.86 1.09 0.10 -0.99 0.28 -1.64 0.48
11834 || orf19.5839 || PDR17 || || Fungal-specific protein (no human or murine homolog); role in sensitivity to fluconazole, specifically || 1 -0.58 -0.55 -0.98 -0.69 -1.17 -1.74 0.19 0.56 -0.41 0.63 0.26 -0.30 0.04 0.22 -0.60 0.01
11835 || orf19.6026 || ERG2 || || C-8 sterol isomerase; enzyme of ergosterol biosynthesis; converts fecosterol to episterol; mutant is hypersensitive to multiple drugs; ketoconazole-induced; flow model and Spider biofilm repressed || 1 -1.05 -0.95 -1.02 -0.56 -1.90 -2.20 -0.05 0.79 -0.27 1.13 0.51 0.15 -0.18 -0.31 -0.88 0.03
11836 || orf19.7631 || SLD5 || || Putative GINS complex subunit; cell-cycle regulated periodic mRNA expression || 1 -0.51 -0.69 -0.70 -0.37 -0.70 -1.47 0.09 0.75 -0.25 0.72 0.06 0.14 -0.17 -0.33 -0.50 -0.22
11837 || orf19.4909 || CBK1 || || Ser/Thr kinase of cell wall integrity pathway; mutants show abnormal morphology and aggregation; Mob2p associated; required for wild-type hyphal growth and transcriptional regulation of cell-wall-associated genes || 1 -0.53 -0.66 -0.95 -0.70 -1.04 -0.76 0.12 0.29 -0.09 0.54 0.24 0.11 -0.29 -0.22 -0.84 -0.16
11838 || orf19.2382 || || || Protein similar to isoleucyl-tRNA synthetase; isoleucyl-tRNA synthetase is the target of drugs including the cyclic beta-amino acid icofungipen/PLD-118/BAY-10-8888 and mupirocin || 1 -1.38 -1.49 -1.46 -1.09 -1.06 -1.15 0.11 0.35 0.49 0.48 -0.19 0.05 -0.78 0.02 -0.54 -0.31
11839 || orf19.2382 || || || Protein similar to isoleucyl-tRNA synthetase; isoleucyl-tRNA synthetase is the target of drugs including the cyclic beta-amino acid icofungipen/PLD-118/BAY-10-8888 and mupirocin || 1 -1.33 -1.39 -1.70 -1.33 -0.76 -1.59 0.10 0.44 0.43 0.37 -0.16 -0.11 -0.67 -0.08 -0.81 -0.92
11840 || orf19.4932 || || || Ortholog(s) have role in mitochondrial translation and mitochondrion localization || 1 -0.82 -0.71 -1.19 -1.11 -0.84 -0.90 0.16 0.22 0.42 0.74 -0.12 -0.40 -0.37 -0.48 -0.49 -0.49
11841 || orf19.6047 || TUF1 || || Translation elongation factor TU; macrophage/pseudohyphal-induced; repressed upon phagocytosis by murine macrophage; levels decrease in stationary phase cells; Spider biofilm repressed || 1 -1.23 -1.14 -1.84 -1.50 -0.85 -1.31 0.53 0.50 0.51 0.57 0.16 -0.24 -0.60 -0.43 -0.22 -0.66
11842 || orf19.6047 || TUF1 || || Translation elongation factor TU; macrophage/pseudohyphal-induced; repressed upon phagocytosis by murine macrophage; levels decrease in stationary phase cells; Spider biofilm repressed || 1 -1.03 -1.11 -1.67 -1.27 -0.88 -1.19 0.70 0.75 0.63 0.56 0.40 -0.17 -0.61 -0.38 -0.36 -0.30
11843 || orf19.6565 || || || Conserved mitochondrial inner membrane insertase; mediates insertion of mitochondrial- and nuclear-encoded proteins from the matrix into the inner membrane; Spider biofilm repressed || 1 -0.94 -0.99 -1.50 -1.07 -1.04 -1.63 0.17 0.70 0.34 0.52 0.17 0.40 -0.44 -0.37 -0.62 -0.50
11844 || orf19.3324 || TIF || || Translation initiation factor; upregulated in highly virulent strain compared to less virulent strain; antigenic in human; flucytosine induced; downregulated upon phagocytosis by macrophages; Spider biofilm repressed || 1 -0.70 -0.77 -1.04 -0.73 -0.92 -1.65 0.53 0.86 0.31 0.39 0.43 0.03 -0.35 -0.13 -0.53 -0.13
11845 || orf19.1031 || HMG1 || || HMG-CoA reductase; enzyme of sterol pathway; inhibited by lovastatin; gene not transcriptionally regulated in response to lovastatin and fluconazole || 1 -1.00 -1.01 -1.16 -0.95 -0.98 -1.76 0.43 0.52 0.00 0.54 0.18 -0.12 -0.42 0.17 -0.79 -0.09
11846 || orf19.1789 || || || Ortholog(s) have mitochondrion localization || 1 -0.96 -0.59 -1.53 -0.95 -0.86 -1.80 0.13 0.41 0.23 0.66 0.41 0.30 -0.03 -0.09 -0.10 -0.38
11847 || orf19.5143 || TIM54 || || Predicted component of the mitochondrial TIM22 complex; involved in protein import into mitochondrial inner membrane; Spider biofilm repressed || 1 -0.54 -0.57 -1.09 -1.43 -0.38 -1.29 0.19 0.69 -0.24 0.32 0.57 -0.39 -0.05 -0.36 -0.07 -0.46
11848 || orf19.2257 || || || Predicted ER protein involved in ER-nucleus signaling; Spider biofilm repressed || 1 -0.81 -0.81 -1.92 -1.49 -1.03 -1.98 0.62 0.74 -0.35 0.01 0.52 -0.28 -0.42 0.00 -0.19 -0.47
11849 || orf19.5164 || ECM39 || || Putative mannosyltransferase similar to S. cerevisiae Ecm39p, which has a role in Calcofluor white resistance; predicted Kex2p substrate; has HKEXRF motif || 1 -0.54 -0.55 -1.06 -1.11 -0.72 -1.18 0.47 0.58 -0.07 0.31 0.26 -0.19 -0.37 0.38 -0.36 -0.22
11850 || orf19.6910 || PSF1 || || Putative GINS complex subunit which is localized to DNA replication origins; implicated in assembly of the DNA replication machinery; flow model biofilm induced || 1 -1.33 -0.67 -2.10 -2.83 -1.93 -3.07 0.38 1.10 -0.41 0.73 0.69 -0.63 -0.13 0.44 -0.77 -0.50
11851 || orf19.5156 || || || Protein similar to S. cerevisiae Phs1p, which is required for growth; has six putative membrane-spanning regions || 1 -0.46 -0.73 -0.97 -0.65 -0.48 -0.98 0.16 0.57 -0.02 0.10 0.16 -0.52 0.16 0.16 -0.43 -0.54
11852 || orf19.5834 || || || Ortholog(s) have protein transporter activity, role in mRNA export from nucleus and cytoplasm, nucleus localization || 1 -0.78 -1.11 -1.60 -1.23 -1.17 -1.62 0.15 0.26 -0.42 0.31 0.25 -0.53 -0.11 -0.41 -0.60 -0.97
11853 || orf19.978 || BDF1 || || Bromodomain transcription factor; repressed upon adherence to polystyrene; reduced mRNA abundance detected in null mutant; macrophage/pseudohyphal-repressed; possibly essential, disruptants not obtained by UAU1 method || 1 -0.75 -0.82 -1.15 -0.91 -1.01 -1.13 0.01 0.15 -0.41 -0.35 0.04 -0.50 0.14 -0.04 -0.35 -0.65
11854 || orf19.6010 || CDC5 || || Polo-like kinase; member of conserved Mcm1 regulon; depletion causes defects in spindle elongation and Cdc35-dependent filamentation; virulence-group-correlated expression; likely essential (UAU1 method); Spider biofilm repressed || 1 -0.61 -0.56 -1.25 -0.94 -1.08 -0.99 0.18 0.24 -0.62 -0.10 0.84 0.07 0.31 0.13 -0.40 0.12
11855 || orf19.6580 || || || Protein of unknown function; Spider biofilm induced || 1 -1.30 -1.24 -1.99 -1.78 -2.77 -1.75 0.60 0.59 -0.21 -0.01 0.88 0.70 0.72 0.10 -0.76 0.04
11856 || orf19.3590 || IPP1 || || Putative inorganic pyrophosphatase; antigenic; soluble protein in hyphae; macrophage-induced protein; protein present in exponential and stationary phase yeast; possibly essential (UAU1 method); sumoylation target; Spider biofilm repressed || 1 -0.22 -0.18 -0.76 -0.30 -0.60 -1.00 0.42 0.31 -0.01 -0.01 0.38 -0.00 0.05 -0.14 -0.39 -0.18
11857 || orf19.2276 || || || Ortholog(s) have DNA-directed RNA polymerase activity, RNA-directed RNA polymerase activity || 1 -0.75 -0.59 -1.85 -0.83 -1.37 -1.98 0.26 0.78 -0.08 0.05 1.10 0.17 0.15 -0.35 -0.27 -0.54
11858 || orf19.6264.4 || || || Ortholog of S. cerevisiae Rpl39; a component of the 60S ribosomal subunit; Hap43-induced; Spider biofilm repressed || 1 -0.73 -0.72 -2.76 -2.12 -2.31 -3.66 1.65 1.60 -0.24 0.48 1.87 0.30 0.49 0.22 0.01 -0.12
11859 || orf19.3061.1 || || || Ortholog of S. cerevisiae Rps22Ap and Rps22Bp; gene contains 5' UTR intron || 1 -1.42 -1.35 -2.69 -1.81 -2.18 -3.61 1.57 1.91 0.19 0.80 2.01 0.37 0.35 0.38 -0.37 -0.04
11860 || orf19.4193.1 || RPS13 || || Putative ribosomal protein of the small subunit || 1 -1.45 -1.50 -2.11 -1.22 -2.83 -3.38 1.29 1.68 -0.08 0.41 1.48 0.51 -0.20 -0.54 -0.25 0.11
11861 || orf19.4193.1 || RPS13 || || Putative ribosomal protein of the small subunit || 1 -1.35 -1.37 -2.30 -1.38 -2.83 -3.62 1.31 1.63 0.10 0.64 1.45 0.26 -0.23 -0.16 -0.54 -0.02
11862 || orf19.3087 || UBI3 || || Fusion of ubiquitin with the S34 protein of the small ribosomal subunit; mRNA decreases upon heat shock, appears to be degraded; functional homolog of S. cerevisiae RPS31; Hap43-induced; Spider biofilm repressed || 1 -1.45 -1.40 -1.78 -3.74 1.39 1.57 -0.01 1.60 0.59 0.08 0.14 0.12 0.24
11863 || orf19.4149.1 || || || Protein component of the small (40S) ribosomal subunit; Spider biofilm repressed || 1 -1.33 -1.28 -2.36 -1.39 -2.96 -4.29 1.29 1.39 0.09 0.41 1.36 0.56 0.14 -0.00 -0.27 0.37
11864 || orf19.2179.2 || RPS10 || || Ribosomal protein S10; downregulated in the presence of human whole blood or PMNs; Spider biofilm repressed || 1 -1.20 -1.16 -2.32 -1.48 -4.03 -4.44 1.15 1.46 0.00 0.49 1.53 0.44 -0.19 0.05 -0.37 -0.05
11865 || orf19.667.1 || RPL37B || || Ribosomal protein L37; Hap43-induced; Spider biofilm repressed || 1 -1.30 -1.25 -2.06 -1.01 -3.11 -3.92 1.09 1.28 0.22 0.48 1.43 0.26 0.08 -0.20 -0.17 0.26
11866 || orf19.2864.1 || RPL28 || || Putative ribosomal protein; Plc1-regulated; downregulated upon phagocytosis by murine macrophage; Spider biofilm repressed || 1 -1.16 -0.94 -1.74 -1.03 -2.94 -3.37 1.18 1.28 0.19 0.37 1.19 0.20 0.10 -0.05 -0.48 0.31
11867 || orf19.840 || RPL21A || || Putative ribosomal protein; repressed upon phagocytosis by murine macrophage; Spider biofilm repressed || 1 -1.40 -1.22 -2.12 -1.37 -3.92 -4.29 1.25 1.46 0.42 0.60 1.45 0.18 0.20 0.06 -0.46 0.22
11868 || orf19.840 || RPL21A || || Putative ribosomal protein; repressed upon phagocytosis by murine macrophage; Spider biofilm repressed || 1 -1.31 -1.29 -2.32 -1.50 -4.00 -4.31 1.27 1.45 0.46 0.63 1.66 0.48 0.05 0.28 -0.31 0.31
11869 || orf19.3087 || UBI3 || || Fusion of ubiquitin with the S34 protein of the small ribosomal subunit; mRNA decreases upon heat shock, appears to be degraded; functional homolog of S. cerevisiae RPS31; Hap43-induced; Spider biofilm repressed || 1 -1.38 -1.36 -2.26 -1.35 -3.87 -4.34 1.38 1.64 0.37 0.56 1.86 0.80 0.15 0.21 -0.02 0.19
11870 || orf19.2179.2 || RPS10 || || Ribosomal protein S10; downregulated in the presence of human whole blood or PMNs; Spider biofilm repressed || 1 -0.94 -0.90 -2.02 -1.20 -3.78 -4.25 1.28 1.54 0.19 0.45 1.74 0.44 0.38 -0.00 -0.24 0.06
11871 || orf19.2179.2 || RPS10 || || Ribosomal protein S10; downregulated in the presence of human whole blood or PMNs; Spider biofilm repressed || 1 -0.85 -0.93 -1.87 -1.23 -3.78 -4.21 1.35 1.61 0.32 0.78 1.63 0.49 0.24 0.22 -0.21 -0.06
11872 || orf19.2179.2 || RPS10 || || Ribosomal protein S10; downregulated in the presence of human whole blood or PMNs; Spider biofilm repressed || 1 -0.80 -0.73 -1.79 -0.92 -3.36 -4.09 1.37 1.60 0.32 0.67 1.75 0.63 0.20 0.30 -0.14 0.24
11873 || orf19.3789 || RPL24A || || Predicted ribosomal protein; downregulated upon phagocytosis by murine macrophage; intron in 5'-UTR; Hap43-induced; Spider biofilm repressed || 1 -0.98 -1.11 -1.78 -1.03 -3.74 -3.94 1.68 1.71 0.34 0.57 1.75 0.60 0.42 -0.18 -0.47 0.31
11874 || orf19.3504 || RPL23A || || Ribosomal protein; downregulated upon phagocytosis by murine macrophage; Hap43-induced; sumoylation target; Spider biofilm repressed || 1 -0.98 -0.85 -1.46 -0.73 -2.45 -3.29 0.90 1.21 0.12 0.43 1.29 0.69 -0.02 0.22 -0.40 0.37
11875 || orf19.6663 || RPS25B || || Ribosomal protein; macrophage/pseudohyphal-induced after 16 h; repressed upon phagocytosis by murine macrophage; transcript positively regulated by Tbf1; 5'-UTR intron; Hap43-induced; Spider biofilm repressed || 1 -0.70 -0.80 -1.73 -1.20 -2.35 -3.63 1.30 1.34 0.11 0.29 1.34 0.14 0.01 -0.14 -0.10 0.18
11876 || orf19.3325.3 || RPS21B || || Ribosomal protein S21; regulated by Nrg1, Tup1; colony morphology-related gene regulation by Ssn6; positively regulated by Tbf1, Hap43; Spider biofilm repressed || 1 -0.69 -0.72 -2.28 -1.68 -3.90 -4.47 1.66 1.76 0.02 0.30 1.80 0.10 0.58 0.25 -0.02 0.33
11877 || orf19.1470 || RPS26A || || Ribosomal protein; regulated by Nrg1, Tup1; repressed upon phagocytosis by murine macrophage; alternatively spliced intron in 5'-UTR; Spider biofilm repressed || 1 -0.90 -0.56 -2.08 -1.41 -3.85 -4.12 2.03 1.79 0.74 0.77 1.70 0.40 0.64 0.27 0.10 0.40
11878 || orf19.3325.3 || RPS21B || || Ribosomal protein S21; regulated by Nrg1, Tup1; colony morphology-related gene regulation by Ssn6; positively regulated by Tbf1, Hap43; Spider biofilm repressed || 1 -0.50 -0.59 -1.79 -1.01 -3.92 -4.15 1.56 1.76 0.38 0.65 1.89 0.61 0.56 0.68 -0.03 0.20
11879 || orf19.4660 || RPS6A || || Ribosomal protein 6A; localizes to cell surface of yeast cells but not hyphae; repressed upon phagocytosis by murine macrophage; possibly essential; Hap43-induced; Spider biofilm repressed || 1 -0.60 -0.50 -2.05 -1.44 -2.37 -3.69 1.63 1.71 0.46 0.71 1.84 0.19 0.45 0.36 0.57 0.34
11880 || orf19.4660 || RPS6A || || Ribosomal protein 6A; localizes to cell surface of yeast cells but not hyphae; repressed upon phagocytosis by murine macrophage; possibly essential; Hap43-induced; Spider biofilm repressed || 1 -1.01 -0.81 -2.92 -1.24 -3.18 -3.81 1.56 1.69 0.41 0.75 1.80 0.42 0.50 0.25 0.14 0.19
11881 || orf19.6085 || RPL16A || || Ribosomal protein; transposon mutation affects filamentous growth; repressed upon phagocytosis by murine macrophages; Hap43-induced; Spider biofilm repressed || 1 -0.94 -0.88 -2.40 -1.44 -2.97 -3.95 1.28 1.33 0.15 0.35 1.54 0.50 0.35 -0.10 0.29 0.41
11882 || orf19.6085 || RPL16A || || Ribosomal protein; transposon mutation affects filamentous growth; repressed upon phagocytosis by murine macrophages; Hap43-induced; Spider biofilm repressed || 1 -1.05 -1.02 -3.05 -3.75 1.26 1.33 0.37 0.49 1.43 0.37 0.47 0.17 0.15 0.68
11883 || orf19.4490 || RPL17B || || Ribosomal protein L17; mutation confers hypersensitivity to 5-FU, tubercidin; repressed upon phagocytosis by macrophage; Hap43-induced; Spider biofilm repressed || 1 -0.99 -1.04 -2.11 -1.43 -3.05 -3.61 1.65 1.58 0.39 0.47 1.50 0.26 0.33 0.17 0.08 0.66
11884 || orf19.5904 || RPL19A || || Ribosomal protein L19; repressed upon phagocytosis by murine macrophages; Hap43-induced gene; Spider biofilm repressed || 1 -0.94 -0.92 -1.65 -1.09 -2.29 -2.76 1.25 1.29 0.61 1.01 0.34 0.11 0.13 -0.01 0.46
11885 || orf19.3415.1 || RPL32 || || Component of the large (60S) ribosomal subunit; Spider biofilm repressed || 1 -1.06 -1.06 -2.13 -1.35 -3.20 -3.65 1.59 1.74 0.32 0.73 1.50 0.78 0.30 0.71 -0.21 0.31
11886 || orf19.6882.1 || || || Ribosomal 60S subunit protein; Spider biofilm repressed || 1 -1.37 -1.32 -2.47 -1.64 -3.54 -4.24 1.47 1.76 0.17 0.49 2.14 0.80 0.13 0.80 -0.07 0.77
11887 || orf19.6882.1 || || || Ribosomal 60S subunit protein; Spider biofilm repressed || 1 -1.32 -1.25 -2.47 -1.64 -3.25 -4.46 1.44 1.74 0.22 0.54 2.18 0.76 0.19 0.51 0.09 0.37
11888 || orf19.3690.2 || || || Ribosomal 60S subunit protein; Spider biofilm repressed || 1 -1.29 -1.35 -2.61 -1.76 -3.55 -4.67 1.62 1.99 0.04 0.78 2.41 0.57 0.32 0.68 0.18 0.47
11889 || orf19.6265 || RPS22A || || Predicted ribosomal protein; repressed upon phagocytosis by murine macrophage; Spider biofilm repressed || 1 -1.23 -1.13 -3.03 -2.04 -2.98 -4.63 1.59 1.87 -0.08 0.55 2.10 0.31 0.68 0.40 0.20 0.34
11890 || orf19.687.1 || RPL25 || || Putative rRNA-binding ribosomal protein component of the 60S ribosomal subunit; Hap43-induced; colony morphology-related gene regulation by Ssn6 || 1 -0.73 -0.64 -2.31 -1.71 -2.96 -4.15 1.72 1.82 0.01 0.44 1.93 0.21 0.57 0.25 0.09 0.43
11891 || orf19.7018 || RPS18 || || Predicted ribosomal protein; repressed upon phagocytosis by murine macrophage; repressed by nitric oxide; Hap43-induced; Spider biofilm repressed || 1 -0.99 -0.93 -2.27 -1.95 -3.15 -3.83 1.73 1.74 -0.06 0.38 1.86 0.46 0.40 0.47 0.03 0.55
11892 || orf19.7018 || RPS18 || || Predicted ribosomal protein; repressed upon phagocytosis by murine macrophage; repressed by nitric oxide; Hap43-induced; Spider biofilm repressed || 1 -1.07 -0.84 -2.42 -1.64 -3.00 -3.77 1.80 1.78 0.23 0.79 1.91 0.56 0.42 0.73 0.20 0.71
11893 || orf19.4660 || RPS6A || || Ribosomal protein 6A; localizes to cell surface of yeast cells but not hyphae; repressed upon phagocytosis by murine macrophage; possibly essential; Hap43-induced; Spider biofilm repressed || 1 -1.01 -0.98 -2.43 -1.67 -3.17 -4.08 1.94 2.02 0.79 2.05 0.82 0.64 0.22 0.74
11894 || orf19.6265 || RPS22A || || Predicted ribosomal protein; repressed upon phagocytosis by murine macrophage; Spider biofilm repressed || 1 -1.10 -1.15 -2.88 -1.89 -2.93 -4.37 1.72 1.93 0.19 0.84 2.15 0.53 0.75 0.56 0.24 0.66
11895 || orf19.5225.2 || RPL27A || || Ribosomal protein L27; Spider biofilm repressed || 1 -0.97 -0.95 -2.31 -1.71 -2.62 -3.64 1.84 1.97 0.33 0.76 2.00 0.55 0.78 0.43 0.41 0.44
11896 || orf19.5225.2 || RPL27A || || Ribosomal protein L27; Spider biofilm repressed || 1 -1.00 -0.89 -2.44 -1.73 -2.75 -3.61 1.85 1.91 0.32 0.58 1.92 0.41 0.57 0.22 0.37 0.22
11897 || orf19.4149.1 || || || Protein component of the small (40S) ribosomal subunit; Spider biofilm repressed || 1 -1.08 -1.08 -2.57 -1.64 -2.84 -4.12 1.67 1.95 0.09 0.33 2.21 0.68 0.28 -0.10 0.24 0.73
11898 || orf19.1409.1 || || || Ribosomal 60S subunit protein L22B; Spider biofilm repressed || 1 -0.79 -1.22 -2.53 -1.58 -2.25 -4.15 1.37 1.51 0.24 0.75 1.41 0.48 0.17 0.18 -0.48 0.14
11899 || orf19.3354 || || || Ortholog(s) have structural constituent of ribosome activity and 90S preribosome, cytosolic small ribosomal subunit, extracellular region, nucleolus localization || 1 -0.95 -0.76 -1.77 -0.94 -1.63 -3.21 0.77 1.16 0.35 0.51 1.11 0.70 -0.07 0.05 -0.33 0.21
11900 || orf19.3942.1 || RPL43A || || Putative ribosomal protein, large subunit; repressed by human whole blood or PMNs; colony morphology-related gene regulation by Ssn6; Spider biofilm repressed || 1 -0.65 -0.62 -1.85 -0.75 -1.93 -3.74 1.19 1.70 0.81 1.31 0.59 0.31 0.16 0.14 0.21
11901 || orf19.5466 || RPS24 || || Predicted ribosomal protein; hyphal downregulated; repressed upon phagocytosis by murine macrophage; transcriptionally activated by Tbf1; Spider biofilm repressed || 1 -0.88 -0.79 -2.00 -1.06 -3.59 -4.30 2.05 1.98 0.76 1.07 2.02 1.09 0.42 0.85 0.51 1.08
11902 || orf19.6220.4 || || || Ribosomal 60S subunit protein; Spider biofilm repressed || 1 -0.82 -0.67 -1.94 -0.83 -3.89 -4.35 2.12 2.24 0.67 0.94 1.97 0.69 0.97 0.36 0.54 0.23
11903 || orf19.1470 || RPS26A || || Ribosomal protein; regulated by Nrg1, Tup1; repressed upon phagocytosis by murine macrophage; alternatively spliced intron in 5'-UTR; Spider biofilm repressed || 1 -0.85 -0.46 -2.01 -1.36 -3.47 -3.98 2.29 2.22 0.73 0.58 2.24 0.63 0.89 0.34 0.32 0.66
11904 || orf19.6220.4 || || || Ribosomal 60S subunit protein; Spider biofilm repressed || 1 -0.87 -0.70 -2.22 -1.35 -3.62 -4.25 2.40 2.40 0.69 0.91 2.26 0.73 1.07 0.31 0.75 0.51
11905 || orf19.4660 || RPS6A || || Ribosomal protein 6A; localizes to cell surface of yeast cells but not hyphae; repressed upon phagocytosis by murine macrophage; possibly essential; Hap43-induced; Spider biofilm repressed || 1 -0.47 -0.52 -1.89 -1.23 -2.66 -3.71 2.06 2.25 0.49 0.71 2.36 0.51 1.00 0.53 0.52 0.48
11906 || orf19.1470 || RPS26A || || Ribosomal protein; regulated by Nrg1, Tup1; repressed upon phagocytosis by murine macrophage; alternatively spliced intron in 5'-UTR; Spider biofilm repressed || 1 -0.23 -0.20 -1.69 -0.84 -3.63 -4.01 2.43 2.51 0.95 1.22 0.67 0.45 0.74
11907 || orf19.7018 || RPS18 || || Predicted ribosomal protein; repressed upon phagocytosis by murine macrophage; repressed by nitric oxide; Hap43-induced; Spider biofilm repressed || 1 -0.37 -0.35 -1.94 -1.29 -2.90 -3.86 2.21 2.49 0.87 0.96 2.25 0.67 0.94 1.00 0.10 0.22
11908 || orf19.7368 || || || Ortholog(s) have mRNA binding, poly(U) RNA binding activity and role in nuclear-transcribed mRNA catabolic process, nonsense-mediated decay, regulation of mRNA stability, stress granule assembly || 1 0.12 -0.48 -0.69 -0.47 -1.03 -1.70 0.50 0.79 0.20 0.49 0.50 -0.10 0.33 0.14 -0.02 -0.08
11909 || orf19.3415.1 || RPL32 || || Component of the large (60S) ribosomal subunit; Spider biofilm repressed || 1 -0.30 -0.27 -1.93 -1.12 -2.62 -4.09 2.04 2.31 0.73 0.93 1.00 -0.10 0.88 0.80 -0.95 -0.41
11910 || orf19.7104 || || || Adhesin-like cell wall protein; similar to mucins and to a Litomosoides microfilarial sheath protein; N-terminal secretion signal; rat catheter and Spider biofilm repressed || 1 -0.27 -0.25 -0.58 -0.43 -1.05 -1.55 0.48 0.70 0.05 0.22 0.29 -0.00 0.11 0.25 -0.25 -0.37
11911 || orf19.2672 || NCP1 || || NADPH-cytochrome P450 reductase, acts with Erg11p in sterol 14 alpha-demethylation in ergosterol biosynthesis; subject to hypoxic regulation; ketoconazole-induced; caspofungin repressed || 1 -0.32 -0.40 -0.89 -0.42 -1.55 -2.11 0.77 0.93 -0.19 0.25 0.48 -0.23 0.20 0.44 -0.55 0.23
11912 || orf19.2672 || NCP1 || || NADPH-cytochrome P450 reductase, acts with Erg11p in sterol 14 alpha-demethylation in ergosterol biosynthesis; subject to hypoxic regulation; ketoconazole-induced; caspofungin repressed || 1 -0.14 -0.24 -0.84 -0.82 -1.26 -2.08 0.61 0.77 -0.31 0.22 0.48 -0.25 0.23 0.34 -0.53 0.09
11913 || orf19.3947 || || || Ortholog(s) have rDNA binding activity || 1 -0.51 -0.31 -0.90 -0.67 -1.34 -1.56 0.48 0.67 -0.25 -0.05 0.53 -0.30 -0.00 0.42 -0.47 -0.16
11914 || orf19.5171 || PMT1 || || Protein mannosyltransferase; required for virulence in mice and for adhesion to epithelial cells; role in hyphal growth and drug sensitivity; Als1, Sec20, Kre9, Pir1 are substrates; 1 of 5 PMT family members || 1 -0.87 -0.77 -0.64 -0.45 -1.54 -1.67 -0.01 0.18 -0.56 0.05 0.14 -0.24 -0.17 0.20 -0.42 0.16
11915 || orf19.5171 || PMT1 || || Protein mannosyltransferase; required for virulence in mice and for adhesion to epithelial cells; role in hyphal growth and drug sensitivity; Als1, Sec20, Kre9, Pir1 are substrates; 1 of 5 PMT family members || 1 -1.00 -0.88 -0.82 -0.61 -1.50 -1.66 0.22 0.40 -0.65 0.31 0.31 -0.04 -0.22 0.27 -0.40 0.30
11916 || orf19.6462 || || || Ortholog(s) have role in protein folding in endoplasmic reticulum and ER membrane protein complex, cytosol localization || 1 -0.51 -0.53 -0.54 -0.56 -0.97 -0.97 0.09 0.26 -0.09 0.21 -0.09 -0.04 -0.35 0.16 -0.16 0.16
11917 || orf19.6810 || || || Ortholog(s) have protein serine/threonine phosphatase activity || 1 -0.52 -0.67 -1.04 -0.88 -1.09 -1.32 0.07 0.25 0.01 -0.03 0.38 0.13 -0.36 0.26 -0.21 0.03
11918 || orf19.4931.1 || RPL14 || || Ribosomal protein L14; promoter bound directly by Tbf1p; Hap43p-induced gene || 1 -1.39 -1.42 -2.69 -1.93 -3.25 -3.93 1.15 1.23 0.04 0.41 1.59 0.48 0.22 0.69 -0.17 0.42
11919 || orf19.5904 || RPL19A || || Ribosomal protein L19; repressed upon phagocytosis by murine macrophages; Hap43-induced gene; Spider biofilm repressed || 1 -1.08 -1.12 -1.88 -1.62 -2.48 -3.17 0.98 0.90 0.30 0.31 0.69 -0.06 -0.03 -0.09 -0.41 0.13
11920 || orf19.4490 || RPL17B || || Ribosomal protein L17; mutation confers hypersensitivity to 5-FU, tubercidin; repressed upon phagocytosis by macrophage; Hap43-induced; Spider biofilm repressed || 1 -1.57 -1.58 -2.48 -1.83 -3.45 -3.77 1.43 1.40 0.22 0.52 1.15 0.59 0.03 0.41 0.10 0.68
11921 || orf19.2994 || RPL13 || || Putative ribosomal subunit; antigenic during murine infection; downregulated upon phagocytosis by murine macrophage; Spider biofilm repressed || 1 -1.74 -1.71 -1.29 -3.77 -3.98 1.41 1.40 1.41 -0.11 0.03 -0.10 0.84
11922 || orf19.2478.1 || || || 60S ribosomal protein L7; snoRNA snR39b encoded within the 2nd intron || 1 -1.14 -1.17 -1.88 -1.16 -3.04 -3.42 0.92 0.92 0.13 0.45 0.98 0.56 -0.31 0.37 -0.42 0.67
11923 || orf19.236 || RPL9B || || Ribosomal protein L9; repressed upon phagocytosis by murine macrophages; repressed by nitric oxide; protein levels decrease in stationary phase; Hap43-induced; Spider biofilm repressed || 1 -1.50 -1.57 -2.32 -1.55 -3.65 -4.65 1.01 1.25 0.02 0.45 1.64 0.77 -0.04 0.36 -0.67 0.17
11924 || orf19.3354 || || || Ortholog(s) have structural constituent of ribosome activity and 90S preribosome, cytosolic small ribosomal subunit, extracellular region, nucleolus localization || 1 -1.46 -1.56 -2.36 -1.51 -3.24 -4.02 0.77 1.20 0.26 0.63 1.30 0.63 -0.43 0.27 -0.70 0.11
11925 || orf19.6785 || RPS12 || || Acidic ribosomal protein S12; regulated by Gcn4, activated by Tbf1; repressed by amino acid starvation (3-AT); protein abundance is affected by URA3 expression in CAI-4 strain background; sumoylation target; Spider biofilm repressed || 1 -1.24 -1.63 -2.02 -1.39 -3.22 -4.37 0.91 1.16 0.26 0.46 0.95 0.23 -0.37 -0.07 -0.67 0.29
11926 || orf19.6403.1 || RPP2A || || Acidic ribosomal protein; likely role in translation elongation regulation; interacts with Rpp1B; 1 of 4 similar ribosomal proteins (Rpp1A, Rpp1B, Rpp2A, Rpp2B); CUG start codon; upstream uORFs; Tbf1-induced; Spider biofilm repressed || 1 -1.26 -1.41 -2.06 -1.50 -3.11 -4.05 0.98 1.06 0.21 0.47 1.24 0.16 -0.22 -0.14 -0.58 0.12
11927 || orf19.4336 || RPS5 || || Ribosomal protein S5; macrophage/pseudohyphal-induced after 16 h; downregulated upon phagocytosis by murine macrophage; Hap43-induced; Spider biofilm repressed || 1 -1.45 -1.48 -2.06 -1.53 -3.59 -4.36 0.94 1.28 0.23 0.58 1.27 0.06 -0.25 -0.02 -0.46 0.04
11928 || orf19.2994.1 || RPS16A || || Putative 40S ribosomal subunit; macrophage/pseudohyphal-induced after 16 h; Spider biofilm repressed || 1 -1.23 -1.22 -1.92 -1.13 -2.91 -3.68 0.97 1.19 0.20 0.53 1.02 0.33 -0.18 0.13 -0.54 0.08
11929 || orf19.6265.1 || RPS14B || || Putative ribosomal protein; repressed upon phagocytosis by murine macrophage; transcript positively regulated by Tbf1; Spider biofilm repressed || 1 -1.51 -1.52 -2.06 -1.21 -3.21 -3.83 0.75 0.94 0.30 0.41 0.96 0.29 -0.23 -0.00 -0.57 0.01
11930 || orf19.6975 || YST1 || || Ribosome-associated protein; antigenic in mice; complements S. cerevisiae yst1 yst2 mutant; similar to laminin receptor; predicted S/T phosphorylation, N-glycosylation, myristoylation, Hap43-, Gcn4-regulated; Spider biofilm repressed || 1 -1.34 -1.37 -2.26 -1.41 -2.97 -3.53 0.75 0.80 0.27 0.95 0.20 -0.39 0.11 -0.48
11931 || orf19.5341 || RPS4A || || Predicted ribosomal protein; repressed upon phagocytosis by murine macrophage; positively regulated by Tbf1; Spider biofilm repressed || 1 -1.49 -1.51 -2.37 -3.58 -4.16 0.94 1.16 0.89 -0.03 -0.35 0.22 -0.79 0.05
11932 || orf19.2994.1 || RPS16A || || Putative 40S ribosomal subunit; macrophage/pseudohyphal-induced after 16 h; Spider biofilm repressed || 1 -1.17 -1.31 -2.03 -1.27 -3.47 -3.82 1.01 1.21 0.02 0.52 1.05 0.25 -0.31 -0.11 -0.73 0.28
11933 || orf19.4149.1 || || || Protein component of the small (40S) ribosomal subunit; Spider biofilm repressed || 1 -1.59 -1.57 -2.43 -1.57 -4.02 -4.53 1.24 1.30 -0.16 0.35 1.25 0.17 -0.02 -0.19 -0.44 0.40
11934 || orf19.6375 || RPS20 || || Putative ribosomal protein; repressed upon phagocytosis by murine macrophage; transcript positively regulated by Tbf1; Spider biofilm repressed || 1 -1.49 -1.70 -2.37 -1.88 -3.46 -4.25 1.05 1.16 -0.04 0.22 1.16 -0.03 -0.20 -0.03 -0.47 0.45
11935 || orf19.4149.1 || || || Protein component of the small (40S) ribosomal subunit; Spider biofilm repressed || 1 -1.62 -1.62 -4.09 1.29 1.38 -0.07 1.30 0.47 -0.06 0.17 -0.38 0.72
11936 || orf19.4632 || RPL20B || || Ribosomal protein L20; repressed upon phagocytosis by murine macrophage; alternatively spliced intron in 5' UTR; Hap43-induced; Spider biofilm repressed || 1 -1.51 -1.47 -2.41 -1.70 -3.47 -3.84 1.22 1.35 0.21 0.54 1.30 0.35 -0.05 0.57 -0.16 0.65
11937 || orf19.4632 || RPL20B || || Ribosomal protein L20; repressed upon phagocytosis by murine macrophage; alternatively spliced intron in 5' UTR; Hap43-induced; Spider biofilm repressed || 1 -1.51 -1.48 -2.55 -1.77 -3.47 -3.85 1.14 1.30 0.27 0.60 1.25 0.41 -0.06 0.54 -0.28 0.58
11938 || orf19.4632 || RPL20B || || Ribosomal protein L20; repressed upon phagocytosis by murine macrophage; alternatively spliced intron in 5' UTR; Hap43-induced; Spider biofilm repressed || 1 -1.61 -1.57 -2.40 -1.59 -3.46 -3.94 1.16 1.30 0.44 0.68 1.24 0.34 -0.07 0.39 -0.31 0.62
11939 || orf19.4632 || RPL20B || || Ribosomal protein L20; repressed upon phagocytosis by murine macrophage; alternatively spliced intron in 5' UTR; Hap43-induced; Spider biofilm repressed || 1 -1.48 -1.51 -2.24 -1.53 -3.48 -3.92 1.16 1.32 0.33 0.57 1.25 0.48 -0.12 0.33 -0.23 0.44
11940 || orf19.4632 || RPL20B || || Ribosomal protein L20; repressed upon phagocytosis by murine macrophage; alternatively spliced intron in 5' UTR; Hap43-induced; Spider biofilm repressed || 1 -1.46 -1.46 -2.25 -1.56 -3.48 -3.96 1.10 1.33 0.29 0.56 1.21 0.45 0.09 0.49 -0.33 0.26
11941 || orf19.5996.1 || RPS19A || || Putative ribosomal protein S19; protein level decreases in stationary phase cultures; Spider biofilm repressed || 1 -1.75 -1.73 -2.75 -1.70 -4.02 -4.62 1.27 1.52 0.10 0.49 1.78 0.44 -0.09 0.34 -0.30 0.41
11942 || orf19.5996.1 || RPS19A || || Putative ribosomal protein S19; protein level decreases in stationary phase cultures; Spider biofilm repressed || 1 -1.58 -1.73 -2.71 -1.79 -3.89 -4.60 1.25 1.49 0.02 0.63 1.66 0.35 -0.10 -0.01 -0.36 0.23
11943 || orf19.6403.1 || RPP2A || || Acidic ribosomal protein; likely role in translation elongation regulation; interacts with Rpp1B; 1 of 4 similar ribosomal proteins (Rpp1A, Rpp1B, Rpp2A, Rpp2B); CUG start codon; upstream uORFs; Tbf1-induced; Spider biofilm repressed || 1 -1.49 -1.55 -2.61 -1.66 -4.05 -4.24 1.21 1.22 0.11 0.54 1.44 0.38 -0.20 -0.08 -0.41 0.37
11944 || orf19.5996.1 || RPS19A || || Putative ribosomal protein S19; protein level decreases in stationary phase cultures; Spider biofilm repressed || 1 -1.96 -1.96 -2.74 -1.79 -4.26 -4.64 1.17 1.30 0.06 0.65 1.65 0.59 -0.15 0.45 -0.52 0.31
11945 || orf19.493 || RPL15A || || Putative ribosomal protein; repressed upon phagocytosis by murine macrophage; positively regulated by Tbf1; Spider biofilm repressed || 1 -2.40 -2.48 -3.17 -2.05 -4.70 -5.11 1.32 1.41 0.21 0.67 1.58 0.78 0.01 0.31 -0.46 0.55
11946 || orf19.6541 || RPL5 || || Ribosomal protein; repressed upon phagocytosis by murine macrophages; Hap43-induced; Spider biofilm repressed || 1 -1.83 -1.89 -2.64 -1.68 -3.65 -4.53 0.69 1.05 -0.08 0.52 1.29 0.37 -0.34 0.33 -0.41 0.56
11947 || orf19.6541 || RPL5 || || Ribosomal protein; repressed upon phagocytosis by murine macrophages; Hap43-induced; Spider biofilm repressed || 1 -1.87 -1.85 -2.99 -2.21 -4.03 -4.74 0.87 1.17 -0.15 0.56 1.39 0.27 -0.31 0.29 -0.19 0.49
11948 || orf19.838.1 || RPS9B || || Predicted ribosomal protein; repressed upon phagocytosis by murine macrophage; transcript possibly regulated upon hyphal formation; Spider biofilm repressed || 1 -1.66 -1.63 -3.64 0.96 1.17 -0.26 1.30 0.32 -0.22 -0.33 -0.43 0.27
11949 || orf19.236 || RPL9B || || Ribosomal protein L9; repressed upon phagocytosis by murine macrophages; repressed by nitric oxide; protein levels decrease in stationary phase; Hap43-induced; Spider biofilm repressed || 1 -1.43 -1.42 -2.80 -2.14 -3.21 -4.47 1.18 1.44 -0.18 0.32 1.82 0.53 -0.20 0.39 -0.45 0.38
11950 || orf19.6882.1 || || || Ribosomal 60S subunit protein; Spider biofilm repressed || 1 -1.45 -1.49 -2.79 -1.89 -2.87 -4.42 1.26 1.55 -0.20 0.14 1.80 0.31 -0.10 0.22 -0.15 -0.08
11951 || orf19.6882.1 || || || Ribosomal 60S subunit protein; Spider biofilm repressed || 1 -1.53 -1.58 -2.82 -1.95 -3.69 -4.73 1.28 1.68 -0.13 0.41 1.89 0.23 0.05 0.26 -0.30 0.00
11952 || orf19.6882.1 || || || Ribosomal 60S subunit protein; Spider biofilm repressed || 1 -1.47 -1.45 -2.84 -2.03 -3.69 -4.83 1.20 1.52 -0.33 0.09 1.86 0.21 -0.01 0.14 -0.20 -0.04
11953 || orf19.3690.2 || || || Ribosomal 60S subunit protein; Spider biofilm repressed || 1 -1.34 -1.42 -3.38 -2.37 -4.01 -5.13 1.50 1.67 -0.44 0.15 2.11 -0.02 -0.04 0.01 0.02 0.05
11954 || orf19.667.1 || RPL37B || || Ribosomal protein L37; Hap43-induced; Spider biofilm repressed || 1 -1.47 -1.41 -2.62 -1.68 -3.74 -4.25 1.15 1.32 -0.24 0.23 1.34 -0.28 0.24 -0.27 -0.38 -0.04
11955 || orf19.3087 || UBI3 || || Fusion of ubiquitin with the S34 protein of the small ribosomal subunit; mRNA decreases upon heat shock, appears to be degraded; functional homolog of S. cerevisiae RPS31; Hap43-induced; Spider biofilm repressed || 1 -1.53 -1.47 -3.12 -2.19 -4.01 -4.81 1.30 1.34 -0.36 0.02 1.51 -0.09 0.10 -0.45 0.00 -0.04
11956 || orf19.3788.1 || RPL30 || || Ribosomal 60S subunit protein; pre-rRNA processing; pre-mRNA alternatively spliced to productive/unproductive transcripts; temp-regulated splicing; colony morphology-related regulation by Ssn6, Tup1, Nrg1 regulated; Spider biofilm repressed || 1 -1.61 -1.70 -3.07 -2.32 -3.43 -4.75 1.36 1.46 -0.11 0.22 1.35 -0.18 0.01 -0.41 -0.29 -0.18
11957 || orf19.2232 || RPL11 || || Ribosomal protein; repressed by phagocytosis; colony morphology-related gene regulation by Ssn6; Hap43-induced; Spider biofilm repressed || 1 -1.64 -1.59 -3.07 -2.08 -3.43 -4.68 0.95 1.45 0.13 1.73 0.13 -0.18 -0.23 0.04 -0.03
11958 || orf19.2232 || RPL11 || || Ribosomal protein; repressed by phagocytosis; colony morphology-related gene regulation by Ssn6; Hap43-induced; Spider biofilm repressed || 1 -1.95 -1.99 -3.45 -2.45 -4.16 -4.99 0.93 1.36 0.03 0.35 1.70 0.20 -0.31 -0.10 -0.00 0.07
11959 || orf19.2232 || RPL11 || || Ribosomal protein; repressed by phagocytosis; colony morphology-related gene regulation by Ssn6; Hap43-induced; Spider biofilm repressed || 1 -2.10 -2.01 -3.39 -2.46 -4.07 -4.93 0.87 1.34 -0.18 0.40 1.62 0.20 -0.41 0.16 -0.07 -0.00
11960 || orf19.2232 || RPL11 || || Ribosomal protein; repressed by phagocytosis; colony morphology-related gene regulation by Ssn6; Hap43-induced; Spider biofilm repressed || 1 -2.11 -2.14 -3.38 -2.46 -4.39 -5.11 0.81 1.38 -0.34 0.26 1.46 0.07 -0.33 0.03 -0.46 -0.33
11961 || orf19.6415.1 || || || Ortholog(s) have structural constituent of ribosome activity and cytosolic small ribosomal subunit, nucleus localization || 1 -1.22 -1.31 -2.58 -1.62 -3.00 -3.74 0.81 0.94 -0.27 0.21 1.02 0.25 -0.30 0.23 -0.56 0.06
11962 || orf19.6415.1 || || || Ortholog(s) have structural constituent of ribosome activity and cytosolic small ribosomal subunit, nucleus localization || 1 -1.19 -1.31 -2.62 -1.71 -3.00 -3.63 0.81 0.94 -0.31 0.29 0.92 0.10 -0.26 0.12 -0.56 0.12
11963 || orf19.6415.1 || || || Ortholog(s) have structural constituent of ribosome activity and cytosolic small ribosomal subunit, nucleus localization || 1 -1.28 -1.31 -2.58 -1.67 -3.01 -3.65 0.76 0.89 -0.39 0.32 0.86 0.23 -0.35 0.21 -0.58 -0.02
11964 || orf19.6415.1 || || || Ortholog(s) have structural constituent of ribosome activity and cytosolic small ribosomal subunit, nucleus localization || 1 -1.24 -1.35 -2.75 -1.75 -2.97 -3.70 0.74 0.92 -0.42 0.29 0.92 -0.03 -0.24 -0.09 -0.58 -0.22
11965 || orf19.6415.1 || || || Ortholog(s) have structural constituent of ribosome activity and cytosolic small ribosomal subunit, nucleus localization || 1 -1.36 -1.47 -2.70 -1.87 -3.04 -3.74 0.81 0.89 -0.42 0.13 0.83 -0.01 -0.55 -0.19 -0.58 0.22
11966 || orf19.4193.1 || RPS13 || || Putative ribosomal protein of the small subunit || 1 -1.71 -1.79 -3.06 -2.09 -3.12 -4.01 0.68 0.97 -0.46 0.21 1.13 -0.20 -0.43 -0.34 -0.60 -0.09
11967 || orf19.4193.1 || RPS13 || || Putative ribosomal protein of the small subunit || 1 -1.69 -1.57 -3.02 -2.02 -3.05 -4.03 0.57 0.79 -0.50 0.03 0.79 -0.36 -0.68 -0.19 -0.61 0.00
11968 || orf19.1409.1 || || || Ribosomal 60S subunit protein L22B; Spider biofilm repressed || 1 -1.65 -1.88 -2.61 -1.71 -3.47 -4.38 0.57 1.54 -0.08 0.51 1.33 0.20 -0.01 -0.33 -1.02 -0.10
11969 || orf19.2935 || RPL10 || || Ribosomal protein L10; intron in 5'-UTR; downregulated upon phagocytosis by murine macrophage; transcription regulated by yeast-hypha switch; Spider biofilm repressed || 1 -1.69 -1.73 -2.51 -1.67 -3.07 -3.32 0.74 0.82 0.03 0.15 0.89 0.12 -0.56 -0.02 -0.01 0.25
11970 || orf19.6312 || RPS3 || || Ribosomal protein S3; Hog1, Hap43-induced; grepressed upon phagocytosis by murine macrophage; present in exponential and stationary phase cells; Spider biofilm repressed || 1 -2.53 -2.63 -3.82 -2.47 -4.02 -4.43 0.35 0.75 -0.13 0.58 0.80 -0.21 -0.64 0.17 -0.82 -0.41
11971 || orf19.2311 || RPL82 || || Predicted ribosomal protein; genes encoding cytoplasmic ribosomal subunits, translation factors, and tRNA synthetases are downregulated upon phagocytosis by murine macrophage || 1 -1.95 -1.99 -2.92 -2.01 -2.91 -3.83 0.51 0.91 -0.08 0.08 0.74 -0.17 -0.53 -0.14 -0.53 -0.18
11972 || orf19.3354 || || || Ortholog(s) have structural constituent of ribosome activity and 90S preribosome, cytosolic small ribosomal subunit, extracellular region, nucleolus localization || 1 -1.99 -2.01 -2.96 -2.22 -3.51 -4.08 0.31 0.48 -0.57 0.03 0.73 0.05 -0.84 -0.55 -0.79 -0.29
11973 || orf19.1601 || RPL3 || || Ribosomal protein, large subunit; induced by ciclopirox olamine treatment; genes encoding cytoplasmic ribosomal subunits are downregulated upon phagocytosis by murine macrophages; Hap43-induced gene; Spider biofilm repressed || 1 -3.16 -3.17 -3.43 -2.28 -4.73 -5.02 0.29 0.49 -0.37 0.08 0.62 -0.22 -1.01 -0.20 -1.13 0.27
11974 || orf19.6375 || RPS20 || || Putative ribosomal protein; repressed upon phagocytosis by murine macrophage; transcript positively regulated by Tbf1; Spider biofilm repressed || 1 -1.76 -1.85 -2.73 -1.96 -4.06 -4.69 0.66 0.64 -0.23 -0.27 0.68 -0.35 -0.41 -0.42 -0.95 -0.35
11975 || orf19.5341 || RPS4A || || Predicted ribosomal protein; repressed upon phagocytosis by murine macrophage; positively regulated by Tbf1; Spider biofilm repressed || 1 -1.72 -1.76 -2.85 -1.99 -3.71 -4.49 0.57 0.72 -0.35 -0.10 0.55 -0.50 -0.53 -0.38 -0.94 -0.37
11976 || orf19.6375 || RPS20 || || Putative ribosomal protein; repressed upon phagocytosis by murine macrophage; transcript positively regulated by Tbf1; Spider biofilm repressed || 1 -1.74 -1.81 -2.72 -2.09 -3.64 -4.45 0.67 0.70 -0.11 0.06 0.72 -0.35 -0.55 -0.29 -0.67 -0.18
11977 || orf19.4684.2 || RPL40B || || Protein with similarity to the ribosomal protein portion of S. cerevisiae Rpl40Bp; colony morphology-related gene regulation by Ssn6; positively regulated by Tbf1; Spider biofilm repressed || 1 -1.80 -1.79 -4.49 0.61 0.56 -0.27 0.10 0.70 0.14 -0.30 0.03 -0.74 0.09
11978 || orf19.3002 || RPS1 || || Putative ribosomal protein 10 of the 40S subunit; elicits host antibody response during infection; transcript induced during active growth; Spider biofilm repressed || 1 -1.90 -2.10 -4.42 0.57 0.52 -0.16 0.19 0.58 -0.06 -0.40 -0.16 -0.87 -0.04
11979 || orf19.5982 || RPL18 || || Predicted ribosomal protein; Plc1p-regulated, Tbf1-activated; repressed upon phagocytosis by murine macrophage; Hap43p-induced; Spider biofilm repressed || 1 -2.07 -2.13 -2.62 -1.82 -3.79 -4.05 0.59 0.78 0.04 0.61 0.38 0.10 -0.56 0.18 -1.23 0.15
11980 || orf19.2329.1 || RPS17B || || Ribosomal protein 17B; downregulated upon phagocytosis by murine macrophages; Hap43-induced; Spider biofilm repressed || 1 -1.65 -1.70 -2.31 -1.74 -3.96 -4.49 0.47 0.56 -0.14 0.31 0.67 -0.17 -0.77 -0.18 -1.06 0.15
11981 || orf19.3002 || RPS1 || || Putative ribosomal protein 10 of the 40S subunit; elicits host antibody response during infection; transcript induced during active growth; Spider biofilm repressed || 1 -2.37 -2.39 -3.00 -1.88 -4.71 -4.87 0.49 0.46 -0.10 0.30 0.35 -0.17 -0.65 -0.16 -0.99 0.25
11982 || orf19.5928 || RPP2B || || Conserved acidic ribosomal protein; possibly involved in regulation of translation elongation; interacts with Rpp1A; 1 of 4 similar C. albicans proteins (Rpp1A, Rpp1B, Rpp2A, Rpp2B); macrophage/pseudohyphal-induced; Spider biofilm repressed || 1 -2.76 -2.88 -5.20 -5.30 0.44 0.60 0.00 0.08 0.76 0.34 -0.90 -0.53 -1.26 -0.10
11983 || orf19.2992 || RPP1A || || Conserved acidic ribosomal protein; likely role in regulation of translation elongation; interacts with Rpp2B; 1 of 4 similar C. albicans ribosomal proteins (Rpp1A, Rpp1Bp, Rpp2A, Rpp2B); Hap43-induced; Spider biofilm repressed || 1 -2.52 -2.58 -3.07 -2.15 -4.84 -5.43 0.37 0.52 0.01 0.29 0.60 0.22 -0.86 -0.09 -1.43 -0.05
11984 || orf19.2992 || RPP1A || || Conserved acidic ribosomal protein; likely role in regulation of translation elongation; interacts with Rpp2B; 1 of 4 similar C. albicans ribosomal proteins (Rpp1A, Rpp1Bp, Rpp2A, Rpp2B); Hap43-induced; Spider biofilm repressed || 1 -2.18 -2.44 -2.70 -1.87 -4.28 -4.70 0.52 0.68 -0.09 0.32 0.70 -0.09 -0.67 -0.62 -1.40 -0.25
11985 || orf19.3334 || RPS21 || || Protein component of the small (40S) subunit; repressed upon phagocytosis by murine macrophage; positively regulated by Tbf1; Spider biofilm repressed || 1 -2.64 -2.57 -2.74 -1.68 -4.06 -4.62 0.31 0.64 0.02 0.32 0.55 -0.08 -0.65 -0.34 -1.20 -0.11
11986 || orf19.2311 || RPL82 || || Predicted ribosomal protein; genes encoding cytoplasmic ribosomal subunits, translation factors, and tRNA synthetases are downregulated upon phagocytosis by murine macrophage || 1 -1.30 -1.48 -1.64 -0.85 -2.57 -3.12 0.38 0.56 0.07 0.29 0.40 -0.04 -0.57 -0.26 -0.79 -0.14
11987 || orf19.2329.1 || RPS17B || || Ribosomal protein 17B; downregulated upon phagocytosis by murine macrophages; Hap43-induced; Spider biofilm repressed || 1 -1.44 -1.44 -2.23 -1.38 -3.76 -4.37 0.74 0.86 -0.04 0.48 0.95 0.22 -0.43 -0.04 -0.85 -0.09
11988 || orf19.236 || RPL9B || || Ribosomal protein L9; repressed upon phagocytosis by murine macrophages; repressed by nitric oxide; protein levels decrease in stationary phase; Hap43-induced; Spider biofilm repressed || 1 -1.96 -1.98 -2.78 -2.32 -4.45 -5.11 0.88 1.00 -0.16 0.43 1.30 0.28 -0.63 0.30 -1.18 -0.18
11989 || orf19.236 || RPL9B || || Ribosomal protein L9; repressed upon phagocytosis by murine macrophages; repressed by nitric oxide; protein levels decrease in stationary phase; Hap43-induced; Spider biofilm repressed || 1 -1.90 -1.83 -3.18 -2.33 -4.66 -5.03 0.75 0.76 -0.35 0.01 1.22 0.15 -0.56 0.23 -0.82 0.02
11990 || orf19.236 || RPL9B || || Ribosomal protein L9; repressed upon phagocytosis by murine macrophages; repressed by nitric oxide; protein levels decrease in stationary phase; Hap43-induced; Spider biofilm repressed || 1 -2.15 -2.15 -3.19 -2.33 -4.89 -5.29 0.69 0.77 -0.44 0.03 1.23 0.31 -0.54 0.11 -0.99 0.17
11991 || orf19.1700 || RPS7A || || Ribosomal protein S7; genes encoding cytoplasmic ribosomal subunits, translation factors, and tRNA synthetases are downregulated upon phagocytosis by murine macrophage; Spider biofilm repressed || 1 -2.05 -2.15 -3.17 -2.15 -4.62 -5.28 0.68 0.91 -0.36 0.33 0.91 -0.15 -0.23 -0.09 -0.86 -0.20
11992 || orf19.1700 || RPS7A || || Ribosomal protein S7; genes encoding cytoplasmic ribosomal subunits, translation factors, and tRNA synthetases are downregulated upon phagocytosis by murine macrophage; Spider biofilm repressed || 1 -2.00 -2.18 -3.01 -2.12 -4.76 -5.50 0.69 1.13 -0.27 0.24 0.94 -0.20 -0.39 -0.21 -0.98 -0.14
11993 || orf19.2329.1 || RPS17B || || Ribosomal protein 17B; downregulated upon phagocytosis by murine macrophages; Hap43-induced; Spider biofilm repressed || 1 -1.44 -1.39 -2.49 -1.82 -4.05 -4.40 0.64 0.77 -0.03 0.36 1.02 -0.10 -0.24 0.06 -0.62 -0.11
11994 || orf19.2329.1 || RPS17B || || Ribosomal protein 17B; downregulated upon phagocytosis by murine macrophages; Hap43-induced; Spider biofilm repressed || 1 -1.58 -1.45 -2.45 -1.75 -4.07 -4.34 0.58 0.67 -0.05 0.22 0.93 -0.12 -0.34 -0.01 -0.63 -0.02
11995 || orf19.2329.1 || RPS17B || || Ribosomal protein 17B; downregulated upon phagocytosis by murine macrophages; Hap43-induced; Spider biofilm repressed || 1 -1.45 -1.48 -2.47 -1.67 -3.95 -4.33 0.57 0.60 0.02 0.34 0.92 0.07 -0.32 0.19 -0.64 0.11
11996 || orf19.6541 || RPL5 || || Ribosomal protein; repressed upon phagocytosis by murine macrophages; Hap43-induced; Spider biofilm repressed || 1 -2.27 -2.30 -3.02 -2.28 -4.59 -5.12 0.71 1.14 -0.06 0.69 1.05 0.16 -0.35 0.58 -0.83 0.19
11997 || orf19.6541 || RPL5 || || Ribosomal protein; repressed upon phagocytosis by murine macrophages; Hap43-induced; Spider biofilm repressed || 1 -2.16 -2.07 -2.91 -2.02 -4.30 -5.04 0.67 1.00 -0.11 0.65 1.03 0.16 -0.49 0.28 -0.67 0.34
11998 || orf19.5341 || RPS4A || || Predicted ribosomal protein; repressed upon phagocytosis by murine macrophage; positively regulated by Tbf1; Spider biofilm repressed || 1 -1.77 -1.91 -2.70 -1.93 -3.66 -4.15 0.77 0.92 -0.19 0.92 0.19 -0.55 0.00 -0.70 0.33
11999 || orf19.5341 || RPS4A || || Predicted ribosomal protein; repressed upon phagocytosis by murine macrophage; positively regulated by Tbf1; Spider biofilm repressed || 1 -1.91 -1.92 -2.44 -1.84 -3.75 -4.18 0.64 0.91 0.12 0.52 0.91 0.14 -0.49 -0.03 -0.87 0.23
12000 || orf19.3504 || RPL23A || || Ribosomal protein; downregulated upon phagocytosis by murine macrophage; Hap43-induced; sumoylation target; Spider biofilm repressed || 1 -1.65 -1.61 -2.15 -1.63 -3.49 -3.89 0.61 0.82 -0.00 0.21 0.99 0.26 -0.60 0.08 -0.58 0.26
12001 || orf19.6375 || RPS20 || || Putative ribosomal protein; repressed upon phagocytosis by murine macrophage; transcript positively regulated by Tbf1; Spider biofilm repressed || 1 -1.69 -1.77 -2.60 -1.68 -3.89 -4.44 0.72 0.76 0.14 0.25 0.82 -0.10 -0.38 -0.18 -0.69 0.01
12002 || orf19.6375 || RPS20 || || Putative ribosomal protein; repressed upon phagocytosis by murine macrophage; transcript positively regulated by Tbf1; Spider biofilm repressed || 1 -1.74 -1.69 -2.60 -1.59 -3.85 -4.29 0.77 0.76 0.30 0.29 0.88 0.16 -0.37 -0.12 -0.66 0.26
12003 || orf19.6975 || YST1 || || Ribosome-associated protein; antigenic in mice; complements S. cerevisiae yst1 yst2 mutant; similar to laminin receptor; predicted S/T phosphorylation, N-glycosylation, myristoylation, Hap43-, Gcn4-regulated; Spider biofilm repressed || 1 -1.57 -1.56 -2.27 -1.65 -3.45 -3.79 0.75 0.79 0.22 0.83 0.07 -0.22 -0.04 -0.61 0.07
12004 || orf19.2309.2 || RPL2 || || Putative 60S ribosomal protein L2; Hap43-induced gene; repressed in infected rabbit kidney in SC5314, but not NGY152, strain background; Spider biofilm repressed || 1 -1.85 -1.99 -2.47 -1.76 -4.34 -4.41 0.70 0.83 0.12 0.28 0.87 0.35 -0.25 0.16 -0.91 0.27
12005 || orf19.4336 || RPS5 || || Ribosomal protein S5; macrophage/pseudohyphal-induced after 16 h; downregulated upon phagocytosis by murine macrophage; Hap43-induced; Spider biofilm repressed || 1 -1.78 -1.85 -2.32 -1.68 -4.13 -4.35 0.74 0.95 0.02 0.43 1.03 0.22 -0.26 -0.25 -0.93 0.26
12006 || orf19.2994.1 || RPS16A || || Putative 40S ribosomal subunit; macrophage/pseudohyphal-induced after 16 h; Spider biofilm repressed || 1 -1.48 -1.59 -2.12 -1.22 -3.72 -3.79 0.76 0.80 -0.08 0.21 0.78 0.26 -0.38 -0.06 -0.60 0.40
12007 || orf19.2994.1 || RPS16A || || Putative 40S ribosomal subunit; macrophage/pseudohyphal-induced after 16 h; Spider biofilm repressed || 1 -1.51 -1.71 -2.07 -1.28 -3.71 -3.87 0.81 0.80 -0.17 0.15 0.68 0.19 -0.46 -0.28 -0.60 0.16
12008 || orf19.838.1 || RPS9B || || Predicted ribosomal protein; repressed upon phagocytosis by murine macrophage; transcript possibly regulated upon hyphal formation; Spider biofilm repressed || 1 -1.71 -1.67 -2.69 -1.65 -3.85 -4.24 0.88 0.94 -0.34 0.37 1.07 0.01 -0.45 -0.56 -0.59 -0.04
12009 || orf19.5996.1 || RPS19A || || Putative ribosomal protein S19; protein level decreases in stationary phase cultures; Spider biofilm repressed || 1 -1.96 -1.96 -3.03 -1.96 -4.42 -4.98 1.01 1.24 -0.22 0.30 1.44 -0.12 -0.25 -0.22 -0.60 -0.18
12010 || orf19.5996.1 || RPS19A || || Putative ribosomal protein S19; protein level decreases in stationary phase cultures; Spider biofilm repressed || 1 -1.93 -2.01 -2.98 -1.83 -4.36 -4.89 1.04 1.21 -0.04 0.39 1.54 0.24 -0.31 -0.06 -0.47 0.15
12011 || orf19.3354 || || || Ortholog(s) have structural constituent of ribosome activity and 90S preribosome, cytosolic small ribosomal subunit, extracellular region, nucleolus localization || 1 -1.75 -1.76 -3.51 0.62 0.81 -0.13 0.15 0.15 -0.59 0.05 -0.65 -0.07
12012 || orf19.1601 || RPL3 || || Ribosomal protein, large subunit; induced by ciclopirox olamine treatment; genes encoding cytoplasmic ribosomal subunits are downregulated upon phagocytosis by murine macrophages; Hap43-induced gene; Spider biofilm repressed || 1 -2.40 -2.58 -2.89 -2.04 -3.88 -4.64 0.94 1.15 0.04 0.40 1.23 0.33 -0.44 0.20 -0.41 0.21
12013 || orf19.493 || RPL15A || || Putative ribosomal protein; repressed upon phagocytosis by murine macrophage; positively regulated by Tbf1; Spider biofilm repressed || 1 -2.58 -2.65 -4.28 -5.36 0.94 0.83 -0.16 0.37 1.08 0.24 -0.31 0.15 -0.64 0.60
12014 || orf19.6873 || RPS8A || || Small 40S ribosomal subunit protein; induced by ciclopirox olamine; repressed upon phagocytosis by murine macrophage; 5'-UTR intron; Hap43-induced; Spider biofilm repressed || 1 -1.91 -1.85 -2.50 -1.84 -3.64 -4.08 0.72 0.72 -0.27 0.10 0.83 -0.10 -0.30 -0.28 -0.74 0.22
12015 || orf19.493 || RPL15A || || Putative ribosomal protein; repressed upon phagocytosis by murine macrophage; positively regulated by Tbf1; Spider biofilm repressed || 1 -3.01 -2.83 -3.73 -2.42 -5.32 -5.56 0.97 0.94 -0.29 0.13 1.17 -0.00 -0.53 -0.37 -0.78 0.10
12016 || orf19.493 || RPL15A || || Putative ribosomal protein; repressed upon phagocytosis by murine macrophage; positively regulated by Tbf1; Spider biofilm repressed || 1 -2.69 -2.73 -3.66 -2.67 -5.27 -5.47 1.11 1.05 -0.27 0.09 1.23 -0.08 -0.46 -0.29 -0.54 0.28
12017 || orf19.6873 || RPS8A || || Small 40S ribosomal subunit protein; induced by ciclopirox olamine; repressed upon phagocytosis by murine macrophage; 5'-UTR intron; Hap43-induced; Spider biofilm repressed || 1 -2.02 -2.05 -2.76 -2.14 -3.98 -4.21 0.57 0.66 -0.12 0.06 0.79 -0.01 -0.72 0.01 -0.72 0.19
12018 || orf19.6002 || RPL8B || || Predicted ribosomal protein; regulated upon yeast-hypha switch; repressed upon phagocytosis by murine macrophage; Spider biofilm repressed || 1 -2.34 -2.61 -3.02 -2.16 -3.81 -4.46 0.60 0.78 -0.04 0.17 0.88 0.03 -0.66 -0.23 -0.88 0.02
12019 || orf19.5982 || RPL18 || || Predicted ribosomal protein; Plc1p-regulated, Tbf1-activated; repressed upon phagocytosis by murine macrophage; Hap43p-induced; Spider biofilm repressed || 1 -1.95 -2.04 -3.28 0.42 0.57 -0.02 0.30 0.66 -0.73 -0.23 -0.58 0.26
12020 || orf19.1601 || RPL3 || || Ribosomal protein, large subunit; induced by ciclopirox olamine treatment; genes encoding cytoplasmic ribosomal subunits are downregulated upon phagocytosis by murine macrophages; Hap43-induced gene; Spider biofilm repressed || 1 -2.94 -2.94 -2.94 -1.92 -4.43 -4.68 0.61 0.86 0.20 0.55 0.71 0.14 -0.78 -0.00 -0.75 0.20
12021 || orf19.6312 || RPS3 || || Ribosomal protein S3; Hog1, Hap43-induced; grepressed upon phagocytosis by murine macrophage; present in exponential and stationary phase cells; Spider biofilm repressed || 1 -2.04 -2.10 -2.72 -1.73 -3.27 -3.84 0.44 0.92 0.09 0.59 1.18 0.31 -0.48 0.05 -0.78 0.36
12022 || orf19.3354 || || || Ortholog(s) have structural constituent of ribosome activity and 90S preribosome, cytosolic small ribosomal subunit, extracellular region, nucleolus localization || 1 -1.65 -1.79 -2.17 -1.46 -3.24 -3.81 0.50 0.90 -0.00 0.53 1.15 0.54 -0.53 -0.07 -0.54 0.38
12023 || orf19.3465 || RPL10A || || Predicted ribosomal protein; downregulated upon phagocytosis by murine macrophages; Hap43-induced; Spider biofilm repressed || 1 -1.95 -1.96 -3.38 -3.72 0.42 0.41 -0.15 -0.01 0.84 0.49 -0.73 -0.06 -0.75 0.10
12024 || orf19.3465 || RPL10A || || Predicted ribosomal protein; downregulated upon phagocytosis by murine macrophages; Hap43-induced; Spider biofilm repressed || 1 -2.14 -2.04 -2.60 -2.11 -3.42 -3.92 0.50 0.41 -0.23 0.04 0.75 0.59 -0.76 -0.13 -0.83 0.43
12025 || orf19.4684.2 || RPL40B || || Protein with similarity to the ribosomal protein portion of S. cerevisiae Rpl40Bp; colony morphology-related gene regulation by Ssn6; positively regulated by Tbf1; Spider biofilm repressed || 1 -1.82 -1.82 -2.56 -1.68 -4.51 -4.50 0.65 0.56 0.03 0.36 0.69 0.56 -0.32 0.62 -0.79 0.41
12026 || orf19.6265.1 || RPS14B || || Putative ribosomal protein; repressed upon phagocytosis by murine macrophage; transcript positively regulated by Tbf1; Spider biofilm repressed || 1 -1.67 -1.58 -2.01 -1.11 -4.14 -4.26 0.71 1.05 0.38 0.53 0.95 0.24 -0.32 -0.04 -0.81 0.30
12027 || orf19.5927 || RPS15 || || Putative ribosomal protein; macrophage/pseudohyphal-induced after 16 h; repressed upon phagocytosis by murine macrophage; Spider biofilm repressed || 1 -1.36 -1.39 -2.22 -1.37 -4.09 -4.43 0.94 1.13 -0.05 0.31 0.70 0.03 0.10 -0.16 -0.85 -0.42
12028 || orf19.2179.2 || RPS10 || || Ribosomal protein S10; downregulated in the presence of human whole blood or PMNs; Spider biofilm repressed || 1 -0.96 -1.02 -2.23 -1.47 -4.05 -4.63 1.18 1.42 -0.15 0.33 1.35 0.03 0.02 -0.42 -0.44 -0.41
12029 || orf19.6253 || RPS23A || || Putative ribosomal protein; repressed upon phagocytosis by murine macrophage; Spider biofilm repressed || 1 -0.79 -1.21 -1.82 -1.34 -2.66 -3.56 0.86 1.17 0.01 0.27 1.51 0.09 -0.08 -0.56 -0.52 -0.58
12030 || orf19.7368 || || || Ortholog(s) have mRNA binding, poly(U) RNA binding activity and role in nuclear-transcribed mRNA catabolic process, nonsense-mediated decay, regulation of mRNA stability, stress granule assembly || 1 -0.82 -1.02 -1.40 -1.00 -1.72 -2.05 0.76 0.71 -0.08 0.45 0.60 -0.13 0.34 0.16 -0.26 -0.39
12031 || orf19.6032 || SPE1 || || Ornithine decarboxylase; enzyme of polyamine biosynthesis; mutant is viable; functionally complements polyamine auxotrophy of S. cerevisiae spe1 mutant; downregulated upon adherence to polystyrene || 1 -0.46 -0.29 -0.85 -0.54 -1.19 -1.62 0.43 0.24 0.18 0.20 0.39 0.34 -0.16 0.22 -0.38 -0.25
12032 || orf19.4606 || ERG8 || || Putative phosphomevalonate kinase; enzyme of the mevalonate pathway of isoprenoid biosynthesis; transcript regulated by Nrg1; possible drug target; not conserved in H. sapiens || 1 -0.44 -0.56 -0.74 -0.49 -1.14 -1.44 0.32 0.38 0.33 0.17 -0.10 0.07 -0.17 0.18 -0.41 0.26
12033 || orf19.5098 || NTG1 || || Protein with strong similarity to both S. cerevisiae Ntg1 and Ntg2 DNA repair glycosylases; transcript induced by iron; Hap43-repressed gene; Spider biofilm induced || 1 -0.76 -0.62 -0.90 -0.57 -1.45 -1.77 0.39 0.19 0.36 0.40 -0.31 -0.10 0.05 0.09 -0.02 -0.23
12034 || orf19.346 || ALT1 || || Putative alanine transaminase; mutation confers hypersensitivity to 5-fluorocytosine (5-FC); rat catheter and flow model biofilm induced || 1 -0.81 -0.70 -1.52 -1.38 -2.94 -2.68 1.15 0.70 0.94 0.04 -0.16 -0.09 0.14 -0.01 0.05 0.18
12035 || orf19.346 || ALT1 || || Putative alanine transaminase; mutation confers hypersensitivity to 5-fluorocytosine (5-FC); rat catheter and flow model biofilm induced || 1 -0.53 -0.21 -1.63 -1.08 -2.13 -2.66 1.04 0.98 1.15 0.03 -0.03 0.15 0.13 -0.04 0.08 -0.03
12036 || orf19.2249 || || || Putative metalloprotease of the mitochondrial inner membrane; expression downregulated in an ssr1 null mutant || 1 -0.96 -0.90 -1.24 -0.69 -0.95 -1.09 0.67 0.88 0.63 0.78 0.41 0.32 0.10 0.43 -0.14 -0.05
12037 || orf19.2249 || || || Putative metalloprotease of the mitochondrial inner membrane; expression downregulated in an ssr1 null mutant || 1 -0.80 -0.89 -1.56 -1.07 -0.88 -1.37 0.64 0.50 0.32 0.97 0.46 -0.24 0.22 0.30 -0.05 -0.22
12038 || orf19.3920 || || || Ortholog(s) have protein disulfide isomerase activity, protein disulfide oxidoreductase activity, role in protein folding and fungal-type vacuole localization || 1 -0.70 -0.82 -1.35 -0.86 -1.09 -1.74 0.35 0.68 -0.13 0.90 0.62 0.18 -0.33 0.54 -0.16 -0.37
12039 || orf19.6584 || PRT1 || || Putative translation initiation factor eIF3; mutation confers hypersensitivity to roridin A, verrucarin A; genes encoding ribosomal subunits, translation factors, tRNA synthetases are downregulated upon phagocytosis by murine macrophages || 1 -0.85 -0.86 -1.20 -1.22 -0.97 -1.59 0.38 0.58 -0.24 0.70 0.71 0.18 -0.27 0.13 -0.10 0.05
12040 || orf19.4809 || ERG12 || || Ortholog(s) have mevalonate kinase activity and role in ergosterol biosynthetic process, farnesyl diphosphate biosynthetic process, mevalonate pathway, isopentenyl diphosphate biosynthetic process, mevalonate pathway || 1 -0.70 -0.86 -1.40 -1.11 -1.28 -1.14 0.23 0.70 -0.28 0.79 0.64 0.46 -0.23 0.33 -0.18 0.37
12041 || orf19.5650 || PRO3 || || Delta 1-pyrroline-5-carboxylate reductase; protein induced during the mating process; alkaline induced; stationary phase enriched protein; Spider biofilm repressed || 1 -0.54 -0.95 -1.70 -1.41 -0.83 -1.59 0.23 0.36 0.04 0.16 0.75 0.45 -0.31 0.16 -0.30 0.32
12042 || orf19.5650 || PRO3 || || Delta 1-pyrroline-5-carboxylate reductase; protein induced during the mating process; alkaline induced; stationary phase enriched protein; Spider biofilm repressed || 1 -0.92 -0.88 -1.66 -1.21 -0.65 -1.62 0.08 0.26 0.01 0.06 0.45 0.34 -0.44 -0.08 -0.20 0.36
12043 || orf19.5195 || URA6 || || Ortholog(s) have adenylate kinase activity, uridylate kinase activity, role in 'de novo' pyrimidine nucleobase biosynthetic process and cytosol, mitochondrion, nucleus localization || 1 -1.09 -1.02 -1.61 -1.47 -0.89 -1.32 0.47 0.24 0.11 -0.05 0.55 -0.06 -0.58 -0.01 -0.42 -0.17
12044 || orf19.2422 || ARC1 || || Putative G4 nucleic acid binding protein; macrophage/pseudohyphal-repressed; protein enriched in stationary phase yeast-form cultures; Spider biofilm repressed || 1 -0.95 -0.99 -1.50 -1.17 -0.62 -1.14 0.57 0.74 -0.05 0.26 0.68 0.13 -0.46 -0.15 -0.21 -0.03
12045 || orf19.1295 || VAS1 || || Putative tRNA-Val synthetase; genes encoding ribosomal subunits, translation factors, and tRNA synthetases are downregulated upon phagocytosis by murine macrophage || 1 -0.94 -0.86 -1.77 -1.26 -1.15 -1.53 1.08 0.93 0.26 0.24 0.89 0.36 -0.42 0.03 -0.45 0.20
12046 || orf19.754 || YBN5 || || P-loop ATPase with similarity to human OLA1 and bacterial YchF; Spider biofilm repressed || 1 -0.73 -0.96 -1.60 -1.32 -1.04 -1.41 0.59 0.79 0.36 0.54 0.64 0.47 -0.53 0.01 -0.40 0.01
12047 || orf19.2934 || || || Similar to S. cerevisiae Bud20; predicted role in cellular bud site selection; rat catheter and Spider biofilm induced || 1 -0.97 -1.06 -1.69 -1.23 -1.26 -1.60 0.61 0.63 -0.09 0.37 0.36 0.28 -0.23 -0.26 -0.82 0.10
12048 || orf19.6749 || KRS1 || || Putative tRNA-Lys synthetase; repressed upon phagocytosis by murine macrophages; stationary phase enriched protein; Spider biofilm repressed || 1 -1.06 -1.13 -1.67 -1.46 -1.18 -1.31 0.67 0.74 -0.05 0.23 0.68 0.20 -0.18 0.30 -0.62 0.00
12049 || orf19.2560 || CDC60 || || Cytosolic leucyl tRNA synthetase; conserved amino acid and ATP binding class I signature, tRNA binding, proofreading motifs; likely essential for growth; interacts with benzoxaborole antifungals; present in exponential and stationary phase || 1 -1.07 -1.00 -1.91 -1.18 -1.36 -1.82 0.97 0.86 0.10 0.20 0.69 0.09 -0.17 0.24 -0.19 0.06
12050 || orf19.1154 || EGD1 || || Putative GAL4 DNA-binding enhancer protein; soluble protein in hyphae; biofilm induced; macrophage/pseudohyphal-induced; equal level of protein in exponential and stationary growth phase yeast cultures; Spider biofilm repressed || 1 -1.48 -1.48 -2.67 -1.80 -1.71 -2.54 0.84 0.94 -0.22 -0.06 1.14 0.35 -0.55 -0.06 -0.58 -0.07
12051 || orf19.2560 || CDC60 || || Cytosolic leucyl tRNA synthetase; conserved amino acid and ATP binding class I signature, tRNA binding, proofreading motifs; likely essential for growth; interacts with benzoxaborole antifungals; present in exponential and stationary phase || 1 -1.24 -1.16 -2.18 -1.66 -1.51 -2.15 0.72 0.67 -0.13 0.23 0.51 -0.09 -0.36 0.14 -0.74 0.11
12052 || orf19.2573 || FRS1 || || Phenylalanyl-tRNA synthetase; possible role in early cell wall biosynthesis; downregulated by phagocytosis by macrophages; possibly essential gene, disruptants not obtained by UAU1 method; protein present in exponential and stationary phase || 1 -0.95 -1.00 -1.75 -1.39 -1.43 -1.82 0.54 0.73 -0.08 0.30 0.55 -0.09 -0.79 0.19 -0.59 0.25
12053 || orf19.5195 || URA6 || || Ortholog(s) have adenylate kinase activity, uridylate kinase activity, role in 'de novo' pyrimidine nucleobase biosynthetic process and cytosol, mitochondrion, nucleus localization || 1 -1.43 -1.63 -2.23 -1.67 -1.40 -1.47 0.54 0.54 0.18 0.38 0.71 0.17 -0.81 0.29 -0.22 0.40
12054 || orf19.6584 || PRT1 || || Putative translation initiation factor eIF3; mutation confers hypersensitivity to roridin A, verrucarin A; genes encoding ribosomal subunits, translation factors, tRNA synthetases are downregulated upon phagocytosis by murine macrophages || 1 -1.79 -1.72 -2.19 -1.75 -1.48 -1.88 0.68 0.63 -0.34 0.81 0.84 0.25 -0.40 0.15 -0.44 0.30
12055 || orf19.6749 || KRS1 || || Putative tRNA-Lys synthetase; repressed upon phagocytosis by murine macrophages; stationary phase enriched protein; Spider biofilm repressed || 1 -1.02 -1.10 -1.32 -1.07 -1.21 -1.28 0.61 0.63 -0.28 0.22 0.56 0.07 -0.29 0.03 -0.88 0.36
12056 || orf19.7057 || GUS1 || || Putative glutamine-tRNA ligase; stationary phase enriched protein; Spider biofilm repressed || 1 -1.62 -1.54 -1.53 -1.42 -1.38 -1.48 0.78 1.11 0.28 0.42 0.68 0.38 -0.79 0.02 -0.65 0.67
12057 || orf19.754 || YBN5 || || P-loop ATPase with similarity to human OLA1 and bacterial YchF; Spider biofilm repressed || 1 -1.11 -1.09 -1.31 -1.11 -0.94 -1.33 0.48 0.74 0.51 0.72 0.64 0.51 -0.37 0.26 -0.54 0.37
12058 || orf19.7057 || GUS1 || || Putative glutamine-tRNA ligase; stationary phase enriched protein; Spider biofilm repressed || 1 -1.48 -1.59 -1.67 -1.29 -1.31 -1.37 0.83 1.10 0.59 0.66 1.19 0.83 -0.68 0.17 -0.43 0.11
12059 || orf19.4650 || ILV6 || || Putative regulatory subunit of acetolacetate synthase; alkaline induced; regulated by Gcn2 and Gcn4; protein present in exponential and stationary growth phase yeast; Spider biofilm repressed || 1 -1.18 -1.18 -1.66 -1.12 -1.50 -1.58 0.87 0.61 0.33 -0.06 0.92 0.80 -0.26 0.17 -0.44 0.43
12060 || orf19.1036 || MNS1 || || Alpha-1,2-mannosidase; processes Man9GlcNAc2 to Man8GlcNAc2 isomer B; member of ER localized glycosyl hydrolase family 47; ER form is converted by Kex2 to cytosolic form; flow model biofilm repressed || 1 -1.05 -1.27 -1.11 -1.26 -1.41 -1.63 0.27 0.50 0.20 0.48 0.63 0.35 -0.15 -0.08 -0.20 0.30
12061 || orf19.5281 || || || Predicted essential RNA-binding G protein; ortholog an effector of mating response pathway in S. cerevisiae; mainly associated with nuclear envelope and ER; flow model and Spider biofilm repressed || 1 -0.77 -0.77 -1.26 -0.47 -0.86 -1.29 0.81 0.80 -0.11 0.33 0.73 0.20 0.33 0.08 -0.04 0.17
12062 || orf19.5281 || || || Predicted essential RNA-binding G protein; ortholog an effector of mating response pathway in S. cerevisiae; mainly associated with nuclear envelope and ER; flow model and Spider biofilm repressed || 1 -0.69 -0.52 -1.17 -0.83 -0.91 -1.29 0.74 0.65 -0.21 0.12 0.67 0.25 0.09 -0.33 -0.26 0.13
12063 || orf19.5281 || || || Predicted essential RNA-binding G protein; ortholog an effector of mating response pathway in S. cerevisiae; mainly associated with nuclear envelope and ER; flow model and Spider biofilm repressed || 1 -0.17 -0.55 -1.01 -0.66 -0.71 -1.16 0.66 0.49 -0.07 0.35 0.56 0.22 0.13 -0.19 -0.04 0.13
12064 || orf19.2560 || CDC60 || || Cytosolic leucyl tRNA synthetase; conserved amino acid and ATP binding class I signature, tRNA binding, proofreading motifs; likely essential for growth; interacts with benzoxaborole antifungals; present in exponential and stationary phase || 1 -0.46 -0.46 -1.49 -1.10 -0.95 -1.85 1.28 1.39 0.18 0.36 1.04 -0.12 0.08 -0.15 -0.07 0.33
12065 || orf19.5943.1 || || || Protein of unknown function; transcript upregulated in an RHE model of oral candidiasis; rat catheter and Spider biofilm repressed || 1 -0.92 -0.89 -1.81 -1.29 -1.04 -1.77 1.12 1.07 0.41 0.29 0.82 0.07 0.25 -0.04 -0.09 0.04
12066 || orf19.2754 || TIM13 || || Predicted mitochondrial intermembrane space protein with a role in protein import into mitochondria || 1 -0.95 -0.85 -1.89 -1.85 -1.17 -2.38 1.21 1.66 0.33 0.57 0.69 -0.23 0.55 0.19 -0.47 -0.09
12067 || orf19.3532 || MRPL10 || || Putative mitochondrial large subunit ribosomal protein; colony morphology-related gene regulation by Ssn6 || 1 -1.38 -1.28 -2.58 -2.12 -1.05 -2.07 1.03 1.12 0.60 0.90 0.97 0.29 -0.25 0.07 0.00 -0.08
12068 || orf19.4605 || TYR1 || || Putative prepephenate dehydrogenase; enzyme of tyrosine biosynthesis; fungal-specific (no human or murine homolog) || 1 -0.58 -0.69 -1.25 -1.09 -0.52 -0.93 0.71 0.64 0.27 0.29 0.52 0.37 -0.24 -0.08 0.06 0.16
12069 || orf19.1154 || EGD1 || || Putative GAL4 DNA-binding enhancer protein; soluble protein in hyphae; biofilm induced; macrophage/pseudohyphal-induced; equal level of protein in exponential and stationary growth phase yeast cultures; Spider biofilm repressed || 1 -1.37 -1.29 -2.03 -1.39 -0.94 -1.72 0.50 0.72 0.10 0.21 1.29 -0.50 0.25 -0.06 0.65
12070 || orf19.5858 || EGD2 || || Nascent polypeptide associated complex protein alpha subunit; soluble protein in hyphae; macrophage/pseudohyphal-induced; protein level decrease in stationary phase cultures; GlcNAc-induced protein; Spider biofilm repressed || 1 -1.53 -1.47 -2.13 -1.74 -1.41 -1.88 0.90 1.24 -0.27 0.49 1.58 0.52 -0.43 -0.13 -0.23 0.58
12071 || orf19.5858 || EGD2 || || Nascent polypeptide associated complex protein alpha subunit; soluble protein in hyphae; macrophage/pseudohyphal-induced; protein level decrease in stationary phase cultures; GlcNAc-induced protein; Spider biofilm repressed || 1 -1.60 -1.64 -2.22 -1.52 -1.35 -2.12 0.84 1.33 0.02 0.46 1.61 0.53 -0.38 0.17 -0.30 0.31
12072 || orf19.5858 || EGD2 || || Nascent polypeptide associated complex protein alpha subunit; soluble protein in hyphae; macrophage/pseudohyphal-induced; protein level decrease in stationary phase cultures; GlcNAc-induced protein; Spider biofilm repressed || 1 -1.46 -1.46 -2.19 -1.50 -1.23 -1.97 1.01 1.39 -0.05 0.49 1.76 0.57 -0.24 0.22 0.11 0.64
12073 || orf19.5858 || EGD2 || || Nascent polypeptide associated complex protein alpha subunit; soluble protein in hyphae; macrophage/pseudohyphal-induced; protein level decrease in stationary phase cultures; GlcNAc-induced protein; Spider biofilm repressed || 1 -1.26 -1.33 -2.09 -1.40 -1.04 -1.89 1.01 1.41 0.09 0.55 1.79 0.51 -0.37 0.26 0.02 0.77
12074 || orf19.3426 || ANB1 || || Translation initiation factor eIF-5A; repressed in hyphae vs yeast cells; downregulated upon phagocytosis by murine macrophage; Hap43-induced; GlcNAc-induced protein; Spider biofilm repressed || 1 -0.86 -0.88 -1.21 -0.79 -0.96 -1.17 0.93 1.00 0.34 0.44 1.14 0.43 -0.01 -0.11 0.21 0.36
12075 || orf19.5281 || || || Predicted essential RNA-binding G protein; ortholog an effector of mating response pathway in S. cerevisiae; mainly associated with nuclear envelope and ER; flow model and Spider biofilm repressed || 1 -0.76 -0.66 -1.27 -0.81 -0.69 -1.12 0.81 0.55 -0.11 0.15 0.75 0.17 0.16 0.14 0.15 0.32
12076 || orf19.2606 || HDA1 || || Histone deacetylase; inducer of filamentation; conserved deacetylation motif; regulates white-to-opaque switch frequency but not opaque-to-white switch; greater expression in white cells than opaque cells; inhibited by trichostatin-A; || 1 -0.72 -0.60 -0.92 -0.79 -0.64 -0.81 0.75 0.37 0.07 -0.10 0.67 0.33 0.20 0.22 0.18 0.27
12077 || orf19.5516 || || || Ortholog(s) have signal sequence binding activity, role in protein targeting to ER and cytosol, nucleus, signal recognition particle, endoplasmic reticulum targeting localization || 1 -0.49 -0.65 -1.39 -1.25 -0.93 -1.32 0.57 0.71 0.06 0.31 0.88 0.20 0.25 0.26 -0.06 -0.29
12078 || orf19.3061.1 || || || Ortholog of S. cerevisiae Rps22Ap and Rps22Bp; gene contains 5' UTR intron || 1 -1.40 -1.21 -2.60 -1.99 -1.22 -2.78 1.17 1.77 -0.02 0.79 1.86 0.59 0.21 0.69 -0.24 0.40
12079 || orf19.5226 || WRS1 || || Putative tRNA-Trp synthetase; genes encoding ribosomal subunits, translation factors, tRNA synthetases are downregulated upon phagocytosis by murine macrophages || 1 -0.62 -0.80 -1.62 -1.39 -0.93 -1.45 0.83 1.02 -0.02 0.82 1.20 0.32 0.27 0.46 0.17 0.49
12080 || orf19.5226 || WRS1 || || Putative tRNA-Trp synthetase; genes encoding ribosomal subunits, translation factors, tRNA synthetases are downregulated upon phagocytosis by murine macrophages || 1 -1.14 -0.75 -1.71 -1.39 -1.20 -1.32 0.95 1.07 0.27 0.88 1.41 0.68 0.46 0.70 0.32 -0.01
12081 || orf19.1624 || || || Non-catalytic subunit of N-terminal acetyltransferase of the NatC type; flow model biofilm repressed || 1 -0.62 -0.56 -1.21 -1.42 -0.86 -1.10 0.91 0.93 0.40 0.71 0.94 0.64 0.27 0.46 -0.19 0.05
12082 || orf19.5243 || TRP3 || || Putative bifunctional enzyme with predicted indole-3-glycerol-phosphate synthase and anthranilate synthase activities; regulated by Gcn2p and Gcn4p || 1 -0.43 -0.42 -0.75 -0.94 -0.75 -1.18 0.82 0.40 0.52 0.23 0.44 0.13 0.22 0.39 -0.36 0.41
12083 || orf19.3099 || TRP4 || || Predicted enzyme of amino acid biosynthesis; upregulated in biofilm; regulated by Gcn2p and Gcn4p; S. cerevisiae ortholog is Gcn4p regulated || 1 -0.77 -0.73 -1.38 -1.38 -1.29 -2.00 1.12 1.04 1.05 0.03 0.88 0.47 -0.13 0.91 -0.40 0.35
12084 || orf19.3099 || TRP4 || || Predicted enzyme of amino acid biosynthesis; upregulated in biofilm; regulated by Gcn2p and Gcn4p; S. cerevisiae ortholog is Gcn4p regulated || 1 -1.14 -1.13 -1.69 -1.62 -1.72 -2.12 1.46 1.17 1.09 -0.09 0.97 0.54 -0.18 0.93 -0.33 0.49
12085 || orf19.2546 || TRP2 || || Putative anthranilate synthase with a predicted role in tryptophan biosynthesis; regulated by Gcn2p and Gcn4p || 1 -0.72 -0.80 -1.49 -1.41 -1.35 -1.60 0.96 0.65 0.45 0.38 0.90 0.12 -0.28 0.59 -0.48 0.66
12086 || orf19.2560 || CDC60 || || Cytosolic leucyl tRNA synthetase; conserved amino acid and ATP binding class I signature, tRNA binding, proofreading motifs; likely essential for growth; interacts with benzoxaborole antifungals; present in exponential and stationary phase || 1 -1.02 -1.01 -1.75 -1.42 -1.28 -1.71 1.04 0.96 0.38 0.58 0.86 0.42 -0.24 0.83 -0.16 0.41
12087 || orf19.5014 || || || Ortholog(s) have mitochondrion localization || 1 -1.06 -0.96 -1.34 -1.29 -1.37 -1.72 0.66 0.74 0.30 0.41 0.76 0.55 -0.12 0.60 -0.20 0.24
12088 || orf19.7328 || || || Protein with a Staphylococcal nuclease domain; transcript regulated by Mig1 and Tup1; flow model and Spider biofilm repressed || 1 -0.66 -0.77 -1.33 -1.14 -0.97 -2.29 0.76 0.86 0.10 0.14 0.58 0.15 -0.21 0.36 -0.47 0.57
12089 || orf19.4704 || ARO1 || || Putative pentafunctional arom enzyme; fungal-specific (no human or murine homolog); Gcn2p-, Gcn4p-regulated || 1 -0.40 -0.56 -0.74 -0.62 -0.59 -1.09 0.51 0.42 0.33 0.05 0.35 -0.05 -0.24 0.03 -0.19 0.20
12090 || orf19.4669 || AAT22 || || Aspartate aminotransferase; nitrogen metabolism; similar but not orthologous to S. cerevisiae Aat2; clade-associated gene expression; protein levels decrease in stationary phase yeast; mutant is viable; flow model biofilm repressed || 1 -2.32 -1.78 -2.26 -2.03 -1.55 -2.97 0.88 1.47 0.32 0.48 0.83 0.35 0.15 0.74 -0.16 -0.29
12091 || orf19.498 || || || Putative mitochondrial ribosomal component of the small subunit; possibly an essential gene, disruptants not obtained by UAU1 method; Spider biofilm repressed || 1 -1.45 -1.40 -1.62 -1.64 -1.17 -1.06 0.38 0.77 0.07 0.96 0.62 0.22 -0.22 0.21 0.02 0.00
12092 || orf19.3481 || || || Putative mitochondrial ATP-dependent RNA helicase of the DEAD-box family, transcription is activated in the presence of elevated CO2 || 1 -1.29 -1.29 -1.46 -1.49 -0.69 -0.85 0.17 0.49 -0.06 0.75 0.92 0.70 -0.17 0.21 0.09 0.37
12093 || orf19.3185 || || || Ortholog(s) have peptide alpha-N-acetyltransferase activity, role in N-terminal protein amino acid acetylation and NatA complex, cytosolic ribosome, mitochondrion localization || 1 -0.72 -0.84 -1.35 -1.36 -0.67 -0.84 0.36 0.53 -0.12 0.23 0.74 0.59 -0.17 0.46 0.03 0.21
12094 || orf19.3185 || || || Ortholog(s) have peptide alpha-N-acetyltransferase activity, role in N-terminal protein amino acid acetylation and NatA complex, cytosolic ribosome, mitochondrion localization || 1 -0.57 -0.63 -1.09 -1.30 -0.66 -0.87 0.26 0.37 -0.03 0.29 0.78 0.26 -0.32 0.06 -0.19 0.22
12095 || orf19.3243 || SRP54 || || Putative signal recognition particle (SRP) subunit; induced in ssr1 null; Spider biofilm repressed || 1 -0.65 -0.67 -1.26 -1.27 -0.61 -1.04 0.23 0.37 -0.25 0.18 0.44 -0.07 0.10 0.09 0.08 -0.15
12096 || orf19.1972 || || || Ortholog(s) have S-adenosylmethionine-dependent methyltransferase activity, role in histone lysine methylation and cytoplasm, nuclear chromatin localization || 1 -1.90 -1.94 -2.70 -2.54 -1.94 -2.54 0.33 0.64 -0.33 0.33 0.26 -0.09 0.16 0.15 0.18 0.22
12097 || orf19.1516 || || || Ortholog(s) have ubiquitin-specific protease activity || 1 -1.00 -1.11 -1.58 -1.34 -0.90 -1.27 0.23 -0.06 -0.33 -0.09 0.21 0.00 -0.22 -0.02 -0.06 0.16
12098 || orf19.1789 || || || Ortholog(s) have mitochondrion localization || 1 -0.86 -1.05 -1.68 -1.84 -1.05 -1.51 0.24 0.30 -0.51 0.14 0.13 0.22 -0.35 0.03 0.08 -0.12
12099 || orf19.1972 || || || Ortholog(s) have S-adenosylmethionine-dependent methyltransferase activity, role in histone lysine methylation and cytoplasm, nuclear chromatin localization || 1 -0.85 -0.85 -1.30 -1.80 -1.29 -1.43 0.20 0.44 0.01 0.49 0.52 0.41 -0.01 0.20 0.50 0.45
12100 || orf19.4650 || ILV6 || || Putative regulatory subunit of acetolacetate synthase; alkaline induced; regulated by Gcn2 and Gcn4; protein present in exponential and stationary growth phase yeast; Spider biofilm repressed || 1 -0.69 -0.90 -1.42 -1.36 -1.15 -1.37 0.31 0.34 0.14 -0.29 0.58 0.50 -0.26 -0.16 0.08 0.52
12101 || orf19.3123.2 || || || Ortholog(s) have cytidine deaminase activity, role in cytidine catabolic process, deoxycytidine catabolic process, pyrimidine-containing compound salvage and cytosol, nucleus localization || 1 -0.49 -0.74 -1.45 -1.36 -0.81 -1.24 0.40 0.50 0.14 -0.03 0.67 0.43 -0.08 0.13 0.62 0.74
12102 || orf19.7269 || || || Putative polyamine acetyltransferase; acetylates polyamines (e.g. putrescine, spermidine, spermine) and aralkylamines (e.g. tryptamine, phenylethylamine); Spider biofilm repressed || 1 -1.40 -1.27 -2.25 -2.11 -0.72 -1.59 0.63 0.52 0.13 0.01 0.63 0.31 -0.13 -0.17 0.50 0.74
12103 || orf19.7269 || || || Putative polyamine acetyltransferase; acetylates polyamines (e.g. putrescine, spermidine, spermine) and aralkylamines (e.g. tryptamine, phenylethylamine); Spider biofilm repressed || 1 -1.62 -1.65 -2.06 -2.28 -0.87 -1.72 0.93 0.92 0.19 -0.07 0.89 0.49 -0.07 -0.11 0.60 0.55
12104 || orf19.3426 || ANB1 || || Translation initiation factor eIF-5A; repressed in hyphae vs yeast cells; downregulated upon phagocytosis by murine macrophage; Hap43-induced; GlcNAc-induced protein; Spider biofilm repressed || 1 -0.98 -0.91 -1.36 -0.69 -0.94 -0.92 0.70 0.83 -0.04 0.01 1.02 0.19 -0.17 -0.42 0.19 0.11
12105 || orf19.3426 || ANB1 || || Translation initiation factor eIF-5A; repressed in hyphae vs yeast cells; downregulated upon phagocytosis by murine macrophage; Hap43-induced; GlcNAc-induced protein; Spider biofilm repressed || 1 -0.93 -0.96 -1.37 -1.15 -0.96 -1.06 0.63 0.72 -0.06 -0.03 1.02 0.03 -0.12 -0.40 0.10 -0.16
12106 || orf19.5493 || GSP1 || || Small RAN G-protein; essential; no prenylation predicted; can rescue S. cerevisiae gsp1 viability; macrophage/pseudohyphal-induced; transcript not regulated by white-opaque, yeast-hypha switching; GlcNAc-induced; Spider biofilm repressed || 1 -0.42 -0.43 -0.96 -0.56 -0.62 -0.48 0.45 0.37 -0.28 -0.04 0.81 0.14 -0.03 -0.13 -0.17 0.03
12107 || orf19.1860.1 || || || Ortholog(s) have extracellular region localization || 1 -0.59 -0.39 -1.34 -1.35 -1.53 -1.38 0.41 0.75 -0.14 0.33 0.76 0.19 -0.35 0.19 -0.83 0.54
12108 || orf19.6717 || || || Putative serine hydrolase; Spider biofilm repressed || 1 -0.68 -0.74 -1.32 -1.25 -1.59 -1.47 0.49 0.76 -0.11 0.32 0.68 -0.25 -0.47 0.15 -0.83 0.36
12109 || orf19.6717 || || || Putative serine hydrolase; Spider biofilm repressed || 1 -0.34 -0.48 -1.03 -0.80 -1.32 -1.25 0.61 1.01 0.17 0.27 0.63 0.05 0.03 0.29 -0.82 0.19
12110 || orf19.3616 || ERG9 || || Putative farnesyl-diphosphate farnesyl transferase (squalene synthase); sterol biosynthesis pathway; likely essential for growth; regulated by fluconazole, lovastatin; amphotericin B, caspofungin repressed; Spider biofilm repressed || 1 -0.71 -1.03 -1.48 -1.34 -1.88 -1.58 0.39 0.80 0.22 -0.24 0.63 -0.17 0.28 0.28 -1.15 0.19
12111 || orf19.6852 || || || Ortholog of Rmd6 involved in S. cerevisiae sporulation; flow model biofilm induced || 1 -0.65 -0.75 -1.05 -0.89 -1.14 -0.89 0.22 0.62 0.25 -0.13 0.16 0.02 -0.18 0.60 -0.72 0.53
12112 || orf19.156 || FGR51 || || Protein lacking an ortholog in S. cerevisiae; transposon mutation affects filamentous growth; Hap43p-repressed gene || 1 -0.79 -1.07 -0.86 -0.88 -1.04 -1.37 0.53 0.49 0.24 -0.14 0.31 0.19 -0.19 0.45 -0.57 0.34
12113 || orf19.5901 || PKC1 || || Protein kinase C; functional homolog of S. cerevisiae Pkc1p; mutant has abnormal yeast-form cell morphology and increased cell lysis; activated by phosphatidylserine; target of antifungal, cercosporamide; R400P mutant is activated || 1 -0.63 -0.66 -1.03 -1.05 -0.86 -1.20 0.22 0.31 -0.11 -0.17 0.04 0.04 -0.40 0.49 -0.53 0.24
12114 || orf19.6702 || DED81 || || Putative tRNA-Asn synthetase; genes encoding ribosomal subunits, translation factors, tRNA synthetases are downregulated upon phagocytosis by murine macrophage; protein enriched in stationary phase yeast cultures || 1 -0.55 -0.49 -0.86 -0.61 -0.38 -1.35 0.41 0.32 0.26 0.25 0.53 0.29 -0.47 0.22 0.00 0.35
12115 || orf19.3802 || PMT6 || || Protein mannosyltransferase; required for virulence in mice, adhesion to endothelium; role in hyphal growth signaling, hygromycin B sensitivity; no major role in cellular PMT activity; Hap4-repressed; Bcr1-repressed in RPMI a/a biofilms || 1 -0.81 -0.80 -1.01 -0.74 -0.92 -1.76 0.12 0.33 0.06 -0.06 0.48 0.40 -0.53 0.09 -0.19 0.77
12116 || orf19.5014 || || || Ortholog(s) have mitochondrion localization || 1 -0.55 -0.49 -0.66 -0.72 -0.81 -0.85 0.27 0.62 0.21 0.09 0.39 0.69 -0.36 0.42 -0.14 0.59
12117 || orf19.6240 || || || SH3-domain protein; role in barrier septum assembly involved in cell cycle cytokinesis; activates the Chs2 chitin synthase activity during cytokinesis; Spider biofilm repressed || 1 -0.34 -0.39 -0.96 -0.57 -1.05 -1.27 0.34 0.54 -0.08 0.00 0.85 0.74 -0.09 0.03 -0.29 0.72
12118 || orf19.6240 || || || SH3-domain protein; role in barrier septum assembly involved in cell cycle cytokinesis; activates the Chs2 chitin synthase activity during cytokinesis; Spider biofilm repressed || 1 -0.22 -0.47 -0.55 -0.42 -0.99 -1.14 0.23 0.57 0.31 0.25 0.63 0.41 0.01 0.33 -0.38 0.58
12119 || orf19.5858 || EGD2 || || Nascent polypeptide associated complex protein alpha subunit; soluble protein in hyphae; macrophage/pseudohyphal-induced; protein level decrease in stationary phase cultures; GlcNAc-induced protein; Spider biofilm repressed || 1 -0.49 -0.56 -0.87 -1.35 0.26 0.57 0.12 1.02 0.52 -0.19 0.18 -0.25 0.42
12120 || orf19.528 || SEC26 || || Secretory vesicles coatomer complex protein || 1 -0.50 -0.30 -0.24 -0.59 -0.76 -0.96 0.25 0.42 0.10 0.21 0.52 0.25 -0.06 0.16 -0.25 0.49
12121 || orf19.5369 || || || Uroporphyrinogen decarboxylase; catalyzes the 5th step in the heme biosynthetic pathway; flow model and Spider biofilm repressed || 1 -0.42 -0.46 -0.43 -0.61 -0.83 -1.03 0.56 0.56 0.17 0.39 0.81 0.25 -0.52 0.16 -0.18 0.74
12122 || orf19.5793 || PR26 || || Protein with similarity to proteasomal 26S regulatory subunit of S. cerevisiae, H. sapiens, Methanobacterium thermoautotrophicum (Archaebacterium) || 1 -0.55 -0.47 -0.50 -0.41 -0.72 -1.02 -0.11 0.24 0.24 0.19 0.16 -0.00 -0.45 0.06 0.00 -0.10
12123 || orf19.3804 || || || Protein of unknown function; filament induced || 1 -0.50 -0.58 -0.97 -0.66 -1.42 -1.46 -0.01 -0.12 -0.25 0.23 0.52 0.47 0.55 0.09 -0.14 0.02
12124 || orf19.3804 || || || Protein of unknown function; filament induced || 1 -0.57 -0.54 -1.23 -0.87 -1.60 -2.04 -0.06 0.20 -0.26 0.36 0.49 0.36 0.53 0.09 -0.03 -0.46
12125 || orf19.6738 || VAN1 || || Member of Mnn9 family of mannosyltransferases; ortholog of S. cerevisiae Van1p; fungal-specific (no human or murine homolog) || 1 -0.45 -0.58 -0.47 -0.31 -1.13 -0.94 0.17 0.29 -0.14 0.28 0.21 0.08 0.53 0.25 -0.32 -0.26
12126 || orf19.4061 || || || Protein of unknown function; clade-associated gene expression || 1 -0.17 -0.55 -0.35 -0.33 -1.00 -1.66 0.41 0.54 0.29 0.36 0.59 -0.04 -0.66 0.28 -0.96 0.13
12127 || orf19.7243 || || || Deoxycytidine monophosphate (dCMP) deaminase; role in dUMP and dTMP biosynthesis; Spider biofilm repressed || 1 -0.41 -0.47 -0.42 -0.16 -0.62 -1.04 0.21 0.59 0.24 0.55 0.43 0.02 -0.49 0.23 -0.42 0.09
12128 || orf19.5685 || THS1 || || Putative threonyl-tRNA synthetase; transcript regulated by Mig1 and Tup1; repressed upon phagocytosis by murine macrophages; stationary phase enriched protein; Spider biofilm repressed || 1 -0.57 -0.63 -0.57 -0.29 -1.37 -1.57 0.49 0.80 0.36 0.66 0.47 0.32 -0.75 0.11 -0.88 0.23
12129 || orf19.5685 || THS1 || || Putative threonyl-tRNA synthetase; transcript regulated by Mig1 and Tup1; repressed upon phagocytosis by murine macrophages; stationary phase enriched protein; Spider biofilm repressed || 1 -0.82 -0.88 -0.65 -0.48 -1.36 -1.49 0.36 0.78 0.37 0.55 0.65 0.51 -0.66 0.08 -1.13 -0.04
12130 || orf19.2960 || FRS2 || || Putative tRNA-Phe synthetase; downregulated upon phagocytosis by murine macrophage; protein present in exponential and stationary growth phase yeast cultures; Spider biofilm repressed || 1 -0.66 -0.69 -0.95 -0.39 -1.10 -1.11 0.41 0.93 0.20 0.65 0.43 0.04 -0.38 0.32 -0.56 -0.32
12131 || orf19.7382 || CAM1 || || Putative translation elongation factor eEF1 gamma; protein level decreased in stationary phase cultures; Spider biofilm repressed || 1 -0.44 -0.59 -0.70 -0.41 -0.87 -1.27 0.45 0.79 0.13 0.49 0.36 -0.34 -0.73 -0.05 -1.14 -0.53
12132 || orf19.6105 || MVD || || Mevalonate diphosphate decarboxylase; functional homolog of S. cerevisiae Erg19; possible drug target; regulated by carbon source, yeast-hypha switch, growth phase, antifungals; gene has intron; rat catheter, Spider biofilm repressed || 1 -0.42 -0.52 -0.69 -0.43 -0.44 -0.63 0.30 0.59 -0.07 0.09 0.34 -0.04 -0.51 -0.11 -0.68 -0.19
12133 || orf19.3065 || DAO1 || || Putative D-amino acid oxidase; transcription is regulated upon yeast-hyphal switch || 1 -0.32 -0.36 -0.94 -0.69 -0.91 -1.04 0.25 0.51 0.34 0.04 0.17 0.05 -0.40 0.24 -0.35 -0.40
12134 || orf19.3065 || DAO1 || || Putative D-amino acid oxidase; transcription is regulated upon yeast-hyphal switch || 1 -0.29 -0.26 -0.55 -0.45 -0.82 -0.77 0.26 0.45 0.44 0.25 0.04 0.32 -0.34 0.50 -0.41 -0.15
12135 || orf19.6779 || PRO2 || || Putative gamma-glutamyl phosphate reductase with a predicted role in proline biosynthesis; regulated by Gcn2p and Gcn4p || 1 -0.78 -0.66 -0.88 -0.67 -1.04 -1.36 0.70 0.57 0.76 0.32 -0.22 0.25 -0.78 0.57 -0.32 0.01
12136 || orf19.6779 || PRO2 || || Putative gamma-glutamyl phosphate reductase with a predicted role in proline biosynthesis; regulated by Gcn2p and Gcn4p || 1 -0.82 -0.67 -0.88 -0.49 -1.09 -1.40 0.81 0.50 0.63 0.27 -0.07 0.14 -0.75 0.16 -0.51 -0.25
12137 || orf19.2951 || HOM6 || || Putative homoserine dehydrogenase; Gcn4-regulated; induced by amino acid starvation (3-ATtreatment); macrophage-induced protein; protein level decreases in stationary phase cultures; flow model biofilm repressed || 1 -0.82 -0.94 -0.67 -0.50 -1.50 -1.54 0.86 0.71 0.36 0.11 -0.03 -0.22 -0.59 -0.03 -0.97 -0.73
12138 || orf19.300 || AIP2 || || Putative actin interacting protein; regulated by Gcn4; induced in response to amino acid starvation (3-AT); repressed by elevated CO2; flow model biofilm repressed || 1 -0.62 -0.77 -0.83 -0.58 -1.55 -1.65 0.81 0.56 0.37 0.17 0.18 -0.22 -0.56 0.25 -0.79 -0.56
12139 || orf19.300 || AIP2 || || Putative actin interacting protein; regulated by Gcn4; induced in response to amino acid starvation (3-AT); repressed by elevated CO2; flow model biofilm repressed || 1 -1.01 -0.89 -0.92 -0.66 -1.85 -1.54 0.63 0.70 0.59 0.05 0.08 -0.09 -0.64 0.09 -1.19 -0.23
12140 || orf19.4172 || || || Has domain(s) with predicted hydrolase activity and role in metabolic process || 1 -0.97 -0.80 -1.21 -0.85 -1.97 -1.56 1.08 0.93 0.56 -0.19 -0.12 -0.02 -0.64 0.42 -1.16 -0.21
12141 || orf19.7244 || || || Putative fumarylacetoacetate hydrolase; induced by nitric oxide independent of Yhb1; regulated by Sef1, Sfu1, Hap43; flow model biofilm induced || 1 -0.67 -0.77 -0.91 -1.01 -1.77 -1.67 1.28 0.50 0.57 -0.53 0.16 0.08 -0.67 0.37 -1.38 0.24
12142 || orf19.4177 || HIS5 || || Putative histidinol-phosphate aminotransferase; Gcn4p-regulated; protein present in exponential and stationary growth phase yeast cultures || 1 -1.02 -0.93 -1.36 -0.92 -2.18 -2.20 1.03 0.51 0.90 -0.43 -0.05 -0.00 -1.18 0.21 -1.21 0.46
12143 || orf19.5870 || CTP1 || || Putative citrate transport protein; flucytosine induced; amphotericin B repressed, caspofungin repressed; Hap43p-induced gene || 1 -0.87 -1.08 -1.01 -1.21 -1.84 -2.01 0.78 0.90 0.98 -0.35 0.27 0.09 -0.56 0.36 -1.03 0.16
12144 || orf19.4704 || ARO1 || || Putative pentafunctional arom enzyme; fungal-specific (no human or murine homolog); Gcn2p-, Gcn4p-regulated || 1 -1.07 -1.01 -0.87 -0.71 -1.16 -1.53 0.50 0.38 0.19 -0.30 0.08 0.17 -0.56 0.16 -0.96 0.10
12145 || orf19.276 || || || Plasma membrane-associated protein; upregulated in an azole-resistant strain that overexpresses MDR1; Hap43-repressed; Spider biofilm induced || 1 -1.44 -1.55 -1.48 -1.07 -2.52 -2.54 0.77 -0.05 1.04 -1.07 0.13 0.46 -0.70 0.07 -1.17 0.23
12146 || orf19.4177 || HIS5 || || Putative histidinol-phosphate aminotransferase; Gcn4p-regulated; protein present in exponential and stationary growth phase yeast cultures || 1 -0.75 -0.98 -0.58 -0.27 -2.26 -1.64 1.02 0.69 1.07 -0.28 0.22 0.25 -0.99 0.33 -1.10 0.74
12147 || orf19.4827 || ADE12 || || Adenylosuccinate synthase; upregulated in biofilm; decreased expression in hyphae vs yeast-form cells; not induced during GCN response, in contrast to S. cerevisiae ADE12, which is induced by Gcn4p; stationary phase-enriched protein || 1 -0.31 -0.20 -0.65 -0.25 -1.04 -0.82 0.49 0.23 0.50 -0.10 0.17 0.26 -0.71 0.16 -0.21 0.35
12148 || orf19.1180 || || || Putative 2-aminoadipate transaminase; rat catheter and Spider biofilm repressed || 1 -0.16 -0.13 -0.33 -0.36 -0.91 -0.75 0.26 0.34 0.34 -0.24 -0.13 -0.02 -0.63 0.14 -0.25 0.21
12149 || orf19.2437 || ARC35 || || Putative ARP2/3 complex subunit; shows colony morphology-related gene regulation by Ssn6p; mutation confers hypersensitivity to cytochalasin D || 1 -0.26 -0.24 -0.66 -0.40 -1.15 -1.33 0.28 0.43 -0.33 -0.20 0.54 0.33 -0.26 0.51 -0.01 0.43
12150 || orf19.3086 || SEC10 || || Ortholog(s) have role in Golgi to plasma membrane transport, cytokinetic cell separation, exocytosis and cell cortex of cell tip, cell division site, cytosol, exocyst, mating projection tip, mitotic spindle pole body, nucleus localization || 1 -0.33 -0.33 -0.65 -0.46 -1.09 -0.92 0.04 0.21 -0.10 -0.18 0.27 0.23 -0.06 0.34 -0.17 0.09
12151 || orf19.2227 || || || Protein of unknown function; flow model biofilm induced; nitric oxide-repressed || 1 -0.44 -0.50 -1.59 -1.07 -3.18 -1.89 0.81 0.87 0.08 -0.36 1.04 0.74 0.40 0.85 -0.45 0.62
12152 || orf19.2763 || || || Protein not essential for viability; orf19.10279 possibly transcriptionally regulated upon hyphal formation || 1 -0.61 -0.52 -1.04 -0.52 -1.60 -1.63 0.39 0.68 -0.43 -0.44 0.72 0.26 0.87 0.24 -0.74 0.45
12153 || orf19.1393 || || || Ortholog(s) have NAD transporter activity, pyruvate secondary active transmembrane transporter activity, role in NAD transmembrane transport, mitochondrial pyruvate transport and endoplasmic reticulum, mitochondrion localization || 1 -0.55 -0.83 -0.52 -0.39 -1.38 -0.92 -0.03 0.14 -0.03 0.04 0.44 0.32 0.31 0.57 -0.22 0.28
12154 || orf19.6738 || VAN1 || || Member of Mnn9 family of mannosyltransferases; ortholog of S. cerevisiae Van1p; fungal-specific (no human or murine homolog) || 1 -0.72 -0.78 -0.63 -0.26 -1.60 -1.15 -0.06 0.11 -0.52 0.09 0.18 -0.20 0.20 -0.01 -0.50 -0.55
12155 || orf19.2036 || || || Predicted dihydrodiol dehydrogenase; ortholog of S. pombe SPAC513.06c; flow model and rat catheter biofilm repressed || 1 -0.85 -0.80 -0.78 -0.24 -1.10 -1.51 -0.38 0.25 -0.55 0.05 -0.03 -0.19 -0.16 -0.28 -0.34 -0.81
12156 || orf19.3920 || || || Ortholog(s) have protein disulfide isomerase activity, protein disulfide oxidoreductase activity, role in protein folding and fungal-type vacuole localization || 1 -0.80 -0.68 -1.10 -0.42 -1.17 -1.92 0.35 0.69 -0.35 0.49 0.11 -0.09 -0.49 -0.26 -0.35 -0.82
12157 || orf19.3920 || || || Ortholog(s) have protein disulfide isomerase activity, protein disulfide oxidoreductase activity, role in protein folding and fungal-type vacuole localization || 1 -0.51 -0.57 -0.76 -0.41 -1.18 -2.18 0.28 0.61 -0.10 0.37 0.38 -0.21 -0.21 -0.05 -0.37 -0.88
12158 || orf19.6217 || PGA63 || || Component COPII vesicle coat; required for vesicle formation in ER to Golgi transport; predicted GPI-anchor; flow model and Spider biofilm repressed || 1 -0.69 -0.56 -0.32 -0.23 -1.11 -0.99 0.28 0.54 -0.12 0.48 0.63 0.23 -0.10 0.45 -0.07 0.09
12159 || orf19.6217 || PGA63 || || Component COPII vesicle coat; required for vesicle formation in ER to Golgi transport; predicted GPI-anchor; flow model and Spider biofilm repressed || 1 -0.70 -0.62 -0.45 -0.08 -1.14 -1.18 0.27 0.62 -0.26 0.24 0.64 0.04 -0.03 0.00 -0.15 0.22
12160 || orf19.1665 || MNT1 || || Alpha-1,2-mannosyl transferase; predicted type II Golgi membrane protein; adds 2nd mannose during cell-wall mannoprotein biosynthesis; required for wild-type virulence and adherence to epithelial cells; Hap43-induced || 1 -0.51 -0.62 -0.41 -0.25 -1.02 -1.16 -0.02 0.70 -0.23 0.33 0.87 0.67 -0.10 -0.15 0.33 0.07
12161 || orf19.4036 || APM1 || || Ortholog of S. cerevisiae/S. pombe Apm1; a clathrin-associated protein complex (AP-1) subunit; phosphorylated protein; Tn mutation affects filamentous growth; Spider biofilm repressed || 1 -0.70 -0.74 -0.96 -0.55 -0.67 -1.09 -0.06 0.46 -0.22 0.52 0.23 0.20 -0.58 -0.10 0.08 0.26
12162 || orf19.895 || HOG1 || || MAP kinase of osmotic-, heavy metal-, and core stress response; role in regulation of glycerol, D-arabitol in response to stress; phosphorylated in response to H2O2 (Ssk1-dependent) or NaCl; mutant induces protective mouse immune response || 1 -0.27 -0.24 -0.58 -0.48 -0.90 -0.68 -0.05 0.18 -0.19 0.10 0.13 0.10 -0.40 0.15 0.17 0.11
12163 || orf19.4956 || RPN1 || || Putative 19S regulatory particle of the 26S proteasome; regulated by Gcn2p and Gcn4p || 1 -0.37 -0.50 -0.45 -0.41 -0.72 -0.69 -0.29 0.05 -0.13 -0.01 0.20 0.16 -0.44 -0.08 0.03 -0.01
12164 || orf19.4230 || || || 20S proteasome subunit (beta7); protein present in exponential and stationary growth phase yeast cultures || 1 -0.19 -0.32 -0.33 -0.15 -0.65 -0.58 -0.14 -0.08 -0.23 0.10 0.17 0.12 -0.38 -0.12 0.10 -0.06
12165 || orf19.544.1 || PRE6 || || Putative alpha-4 subunit of the proteasome; reported as macrophage-induced protein and macrophage/pseudohyphal-repressed gene; regulated by Gcn2p and Gcn4p; removed from/reinstated in Assembly 20 (see Locus History) || 1 -0.15 -0.16 -0.37 -0.12 -0.88 -1.05 -0.14 0.24 -0.42 -0.06 0.12 -0.14 -0.74 0.02 -0.02 0.06
12166 || orf19.993 || || || Protein of unknown function; rat catheter biofilm repressed || 1 -0.63 -0.40 -0.50 -0.58 -0.81 -1.12 -0.19 0.32 -0.59 -0.02 0.17 -0.01 -0.91 -0.15 -0.33 0.33
12167 || orf19.1736 || || || Protein of unknown function; transcript detected on high-resolution tiling arrays || 1 -0.29 -0.76 -0.96 -0.95 -1.13 -1.78 -0.26 0.20 0.22 0.58 0.57 -0.18 -0.62 -0.50 -0.64 0.41
12168 || orf19.2844 || APL4 || || Predicted gamma-adaptin, large subunit of the clathrin-associated protein (AP-1) complex; that binds clathrin and is involved in vesicle mediated transport; induced in core caspofungin response; rat catheter biofilm repressed || 1 -0.65 -0.24 -0.77 -1.00 -0.59 -1.36 0.35 0.18 -0.37 -0.19 0.84 0.18 -0.34 -0.23 -0.43 0.54
12169 || orf19.6880 || COG4 || || Ortholog(s) have role in CVT pathway, macroautophagy, peroxisome degradation, retrograde transport, vesicle recycling within Golgi and Golgi transport complex, cell division site, cell tip, nucleus localization || 1 -0.29 -0.43 -0.55 -0.79 -0.19 -1.02 0.15 -0.09 -0.21 0.05 0.53 0.17 -0.13 0.07 -0.09 0.37
12170 || orf19.7604 || || || Ortholog(s) have Rab guanyl-nucleotide exchange factor activity || 1 -0.49 -0.42 -0.51 -0.78 -0.05 -1.01 -0.05 0.30 -0.55 0.31 0.55 -0.01 -0.04 0.14 -0.17 0.12
12171 || orf19.6438 || || || Ortholog(s) have serine C-palmitoyltransferase activity, role in sphingolipid biosynthetic process and SPOTS complex localization || 1 -0.45 -0.32 -0.84 -0.56 -0.29 -1.25 -0.05 0.33 -0.35 0.57 0.28 0.10 0.02 0.37 -0.28 0.25
12172 || orf19.491 || || || Endoplasmic reticulum (ER) protein-translocation complex subunit || 1 -0.23 -0.16 -0.16 -0.31 -0.72 -0.69 0.11 0.32 -0.29 0.39 0.17 -0.17 -0.13 -0.10 -0.12 -0.09
12173 || orf19.491 || || || Endoplasmic reticulum (ER) protein-translocation complex subunit || 1 -0.34 -0.29 -0.29 -0.31 -0.82 -0.93 0.02 0.25 -0.49 0.16 -0.02 -0.19 -0.25 -0.38 -0.24 0.12
12174 || orf19.2533.1 || || || Protein with a predicted role in protein translocation from the endoplasmic reticulum || 1 -0.28 -0.38 -0.65 -0.15 -1.21 -1.54 0.01 0.57 -0.96 0.09 0.68 -0.12 -0.22 -0.94 -0.42 -0.13
12175 || orf19.7035 || RFC2 || || Putative heteropentameric replication factor C subunit; periodic mRNA expression, peak at cell-cycle G1/S phase || 1 0.00 0.06 -0.75 -0.74 -1.19 -1.81 0.21 0.69 -0.89 0.14 0.82 -0.22 -0.36 -0.65 -0.60 0.01
12176 || orf19.3947 || || || Ortholog(s) have rDNA binding activity || 1 -0.27 -0.38 -0.41 -0.61 -1.03 -1.13 0.16 0.68 -0.18 -0.13 0.60 0.07 -0.12 -0.29 -0.43 0.14
12177 || orf19.5792 || SMP3 || || Mannosyltransferase of glycosylphosphatidylinositol (GPI) biosynthesis; catalyzes mannosylation of Man3-GPI precursor; essential for viability; 8-9 transmembrane regions predicted; has HQEXRF motif; functional homolog of S. cerevisiae Smp3p || 1 -0.18 -0.54 -0.90 -0.41 -0.53 -1.80 0.56 0.98 0.05 0.52 0.10 -0.39 0.05 0.47 -0.54 -0.22
12178 || orf19.5792 || SMP3 || || Mannosyltransferase of glycosylphosphatidylinositol (GPI) biosynthesis; catalyzes mannosylation of Man3-GPI precursor; essential for viability; 8-9 transmembrane regions predicted; has HQEXRF motif; functional homolog of S. cerevisiae Smp3p || 1 -0.37 -0.47 -1.12 -0.45 -0.25 -1.79 0.31 0.70 0.02 0.51 -0.01 -0.21 -0.10 0.46 -0.63 -0.59
12179 || orf19.3536 || || || Ortholog(s) have acetylglucosaminyltransferase activity, role in protein N-linked glycosylation and Golgi medial cisterna localization || 1 -0.65 -0.64 -0.84 -0.64 -0.08 -1.39 0.08 0.24 -0.40 0.71 -0.01 -0.54 -0.18 0.81 -0.40 -0.55
12180 || orf19.4002 || DUN1 || || Protein similar to S. cerevisiae Dun1p, which is a serine-threonine protein kinase involved in DNA damage cell-cycle checkpoint; induced under Cdc5p depletion || 1 -0.33 -0.46 -0.67 -0.44 -0.12 -0.97 0.05 0.25 -0.44 0.20 0.04 -0.30 -0.16 0.08 -0.34 -0.18
12181 || orf19.169 || CHO2 || || Putative phosphatidyl-ethanolamine N-methyltransferase; fungal-specific (no human or murine homolog); amphotericin B repressed; Hap43p-induced gene || 1 -0.83 -0.93 -2.20 -1.93 -0.95 -2.41 0.63 1.53 -0.48 1.21 0.01 -1.28 -0.76 0.80 -1.31 -0.63
12182 || orf19.5557 || MNN4-4 || || Mannosyltransferase; transcript upregulated in Ssk1 response regulator mutant or in nik1 null mutant, but not in chk1 or sln1 null mutants; pheromone induced; Spider biofilm induced || 1 -1.40 -1.24 -2.56 -2.75 -1.04 -2.24 1.46 1.58 0.37 1.48 -0.24 -1.66 -0.52 0.78 -1.34 -1.42
12183 || orf19.401 || TCP1 || || Chaperonin-containing T-complex subunit, induced by alpha pheromone in SpiderM medium; stationary phase enriched protein || 1 -1.14 -0.85 -1.24 -0.44 -0.70 -1.14 -0.17 0.77 -0.38 0.70 0.07 -0.47 -0.52 0.14 -0.89 0.02
12184 || orf19.2183 || KRE30 || || YEF3-subfamily ABC family protein; predicted not to be a transporter; repressed in core stress response; mutation confers hypersensitivity to amphotericin B || 1 -0.70 -0.83 -1.20 -1.20 -0.62 -0.98 -0.20 0.34 -0.67 0.94 0.43 -0.30 0.14 0.19 -1.09 -0.07
12185 || orf19.6751 || || || Ortholog(s) have tRNA methyltransferase activity, role in cytoplasmic translation, tRNA methylation and cytoplasm localization || 1 -0.47 -0.43 -0.77 -0.88 -0.23 -0.40 0.16 0.02 -0.29 0.57 0.12 -0.20 0.16 -0.11 -0.26 -0.46
12186 || orf19.3141 || || || Ortholog(s) have role in ER to Golgi vesicle-mediated transport and cytoplasmic mRNA processing body, endoplasmic reticulum membrane, extrinsic to membrane localization || 1 -0.63 -0.57 -0.90 -0.75 -0.14 -0.52 0.08 0.13 -0.36 0.36 0.08 0.01 0.13 0.15 -0.07 -0.64
12187 || orf19.150 || TIM17 || || Predicted component of the Translocase of the Inner Mitochondrial membrane (TIM23 complex), involved in protein import into mitochondria || 1 -0.81 -0.74 -1.19 -0.85 -0.12 -0.73 0.08 0.20 -0.23 0.41 0.05 0.20 -0.05 0.15 0.28 -0.51
12188 || orf19.1836 || APN2 || || Putative class II abasic (AP) endonuclease; flucytosine induced || 1 -0.65 -0.77 -1.34 -0.80 -0.40 -1.00 -0.09 -0.06 -0.35 0.50 -0.11 0.38 -0.19 -0.07 0.01 -0.55
12189 || orf19.825 || GCD7 || || Putative translation initiator; downregulated in the presence of human whole blood or polymorphonuclear (PMN) cells || 1 -0.62 -0.49 -1.51 -1.04 -0.56 -0.83 -0.20 0.11 -0.37 0.29 0.07 -0.07 0.03 0.16 -0.13 -0.53
12190 || orf19.1361 || TIM23 || || Protein involved in mitochondrial matrix protein import || 1 -0.90 -1.12 -1.63 -1.41 -1.22 -1.35 -0.14 0.14 -0.42 0.81 -0.06 -0.01 -0.53 -0.14 -0.17 -1.26
12191 || orf19.7358 || SAM50 || || Predicted component of the SAM complex involved in mitochondrial protein import || 1 -1.17 -1.12 -1.54 -1.52 -0.99 -0.95 -0.31 0.07 -0.17 0.43 -0.12 0.36 -0.11 0.44 -0.41 -0.52
12192 || orf19.4190 || PAM18 || || Predicted component of the presequence translocase-associated import motor (PAM complex) involved in protein import into mitochondrial matrix; rat catheter biofilm induced || 1 -0.94 -0.80 -1.36 -0.78 -0.42 -0.42 0.03 -0.11 -0.21 0.69 -0.47 0.01 0.05 0.01 -0.04 -0.37
12193 || orf19.2387 || || || Putative tRNA-Pro synthetase; genes encoding ribosomal subunits, translation factors, and tRNA synthetases are downregulated upon phagocytosis by murine macrophage || 1 -0.44 -0.69 -1.15 -1.15 -0.71 -0.62 0.13 0.18 -0.06 0.65 -0.22 0.01 -0.56 0.06 -0.26 -0.25
12194 || orf19.4190 || PAM18 || || Predicted component of the presequence translocase-associated import motor (PAM complex) involved in protein import into mitochondrial matrix; rat catheter biofilm induced || 1 -1.54 -1.38 -1.90 -1.59 -1.43 -1.73 0.38 0.29 -0.10 1.08 -1.01 -0.77 -0.09 0.11 -0.24 -1.52
12195 || orf19.6133 || PIF1 || || Putative DNA helicase; decreased transcription is observed upon fluphenazine treatment || 1 -0.48 -0.76 -0.77 -0.23 -0.46 -0.25 -0.21 0.08 -0.40 0.63 -0.01 -0.19 -0.57 0.24 -0.63 -0.29
12196 || orf19.4587 || HGH1 || || Putative HMG1/2-related protein; transcript regulated by Mig1 || 1 -0.70 -0.78 -1.30 -1.18 -0.80 -0.47 0.19 0.65 -0.23 1.18 0.69 0.15 -1.16 0.63 -0.30 -0.04
12197 || orf19.3541 || ERF1 || || Putative translation release factor 1, which interacts with stop codons and promotes release of nascent peptides from ribosomes; Hap43p-induced gene || 1 -0.74 -0.82 -1.12 -0.73 -0.96 -0.43 -0.42 0.12 -0.66 0.73 0.31 0.27 -0.68 0.27 -0.25 -0.06
12198 || orf19.3057 || || || Ortholog(s) have role in mitochondrial genome maintenance and endoplasmic reticulum localization || 1 -0.48 -0.59 -0.83 -0.64 -0.19 -0.86 -0.21 0.25 -0.23 0.59 0.12 0.28 -0.99 -0.15 -0.22 -0.27
12199 || orf19.2417 || SMC5 || || Protein similar to S. cerevisiae Smc5p, which is involved in DNA repair; transposon mutation affects filamentous growth || 1 -0.62 -0.06 -0.98 -0.75 -0.31 -0.88 -0.46 0.43 -0.34 0.68 0.56 0.04 -0.94 0.03 -0.65 -0.34
12200 || orf19.1031 || HMG1 || || HMG-CoA reductase; enzyme of sterol pathway; inhibited by lovastatin; gene not transcriptionally regulated in response to lovastatin and fluconazole || 1 -0.74 -0.64 -0.67 -0.46 -0.12 -1.48 -0.09 0.06 0.05 0.29 0.15 0.33 -0.20 -0.20 0.05 -0.08
12201 || orf19.6524 || TOM40 || || Protein involved in mitochondrial protein import; Spider biofilm repressed || 1 -0.34 -0.41 -0.17 -0.22 -0.45 -0.89 0.13 0.40 0.29 0.35 0.28 0.30 -0.41 -0.30 -0.24 -0.28
12202 || orf19.756 || SAP7 || || Pepstatin A-insensitive secreted aspartyl protease; self-processing; expressed in human oral infection; Ssn6p-regulated; role in murine intravenous infection; induced during, but not required for, murine vaginal infection; N-glycosylated || 1 -1.85 -1.51 -2.28 -1.57 -1.93 -3.70 -0.12 0.42 0.48 1.56 0.30 -0.44 -1.76 -2.38 -1.86 -1.40
12203 || orf19.756 || SAP7 || || Pepstatin A-insensitive secreted aspartyl protease; self-processing; expressed in human oral infection; Ssn6p-regulated; role in murine intravenous infection; induced during, but not required for, murine vaginal infection; N-glycosylated || 1 -0.46 -0.56 -1.52 -1.25 -1.10 -2.80 0.33 0.51 0.26 1.26 0.31 -0.50 -1.20 -1.88 -0.98 -1.48
12204 || orf19.7386 || || || Ortholog(s) have ribosome binding activity || 1 -0.66 -0.62 -0.42 -0.80 -0.26 -1.00 0.08 0.25 0.20 0.62 -0.08 0.08 -0.26 -0.26 -0.07 -0.68
12205 || orf19.3227 || FTH2 || || Putative iron transporter; similar to S. cerevisiae Fth1p || 1 -1.05 -0.94 -0.46 -0.55 -0.21 -1.10 -0.29 0.01 0.01 0.65 0.02 0.08 -0.13 -0.42 -0.31 -0.85
12206 || orf19.3227 || FTH2 || || Putative iron transporter; similar to S. cerevisiae Fth1p || 1 -0.28 -0.35 -0.56 -0.20 -0.49 -0.69 -0.28 -0.14 -0.14 0.50 -0.16 0.34 -0.28 -0.51 -0.11 -0.24
12207 || orf19.2649 || PCL1 || || Cyclin homolog; transcript induced by filamentous growth; induced by alpha pheromone in SpiderM medium || 1 -1.05 -1.15 -1.40 -1.52 -2.12 -2.77 0.54 0.14 -0.17 0.03 -0.06 0.18 0.26 -1.72 0.43 -0.83
12208 || orf19.2649 || PCL1 || || Cyclin homolog; transcript induced by filamentous growth; induced by alpha pheromone in SpiderM medium || 1 -0.56 -0.85 -1.42 -1.00 -1.26 -1.41 0.72 0.22 0.43 0.76 -0.02 0.18 0.47 -0.99 0.14 -0.73
12209 || orf19.1162 || || || Protein of unknown function; transcript upregulated by benomyl treatment || 1 -0.40 -0.38 -0.73 -0.99 -0.74 -0.30 0.70 0.31 0.50 -0.51 -0.05 -0.20 -0.35 0.03 0.01 -0.47
12210 || orf19.2446 || || || Ortholog(s) have cell division site, cell tip, cytoplasm, nucleus localization || 1 -0.76 -0.81 -1.54 -1.48 -1.29 -0.94 1.24 0.64 0.79 -0.80 -0.18 -0.09 -0.47 -0.12 -0.19 -0.29
12211 || orf19.2446 || || || Ortholog(s) have cell division site, cell tip, cytoplasm, nucleus localization || 1 -0.58 -0.69 -1.29 -1.29 -1.45 -1.01 1.49 0.79 1.05 -0.41 -0.06 -0.13 -0.34 0.22 -0.33 -0.15
12212 || orf19.3115 || || || Protein of unknown function; rat catheter and Spider biofilm induced || 1 -0.62 -0.48 -0.87 -0.49 -0.35 -1.00 1.07 0.28 0.54 -0.56 0.32 -0.17 -0.32 -0.30 -0.33 -0.21
12213 || orf19.780 || DUR1,2 || || Urea amidolyase; hydrolyzes urea to CO2; use of urea as N source and for hyphal switch in macrophage; regulated by Nrg1/Hap43; required for virulence; promotes mouse kidney and brain colonization; rat catheter and flow model biofilm induced || 1 -1.02 -0.74 -0.91 -1.03 -0.82 -0.90 1.43 0.67 1.05 -0.82 0.25 0.26 -0.34 0.71 -0.43 0.28
12214 || orf19.1108 || HAM1 || || Putative deoxyribonucleoside triphosphate pyrophosphohydrolase; caspofungin repressed; regulated by Gcn2p and Gcn4p || 1 -0.55 -0.57 -0.96 -1.02 -0.44 -0.29 1.12 0.51 0.56 -0.24 0.50 0.45 -0.67 0.40 -0.61 0.19
12215 || orf19.2335 || || || Putative aspartyl aminopeptidase; stationary phase enriched protein; mutation confers hypersensitivity to 5-fluorouracil (5-FU); Hog1-induced; planktonic growth-induced; rat catheter and Spider biofilm repressed || 1 -0.66 -0.76 -1.17 -1.12 -0.75 -0.53 1.02 0.71 0.48 -0.80 0.94 0.71 -0.35 -0.15 -0.81 0.62
12216 || orf19.2988 || || || Predicted aminotransferase based on S. pombe ortholog SPBC660.12c; flow model biofilm induced || 1 -0.61 -0.58 -0.85 -1.01 -0.46 -0.33 0.83 0.44 0.89 -0.98 0.47 0.40 -0.06 -0.22 -0.87 0.03
12217 || orf19.797 || BAT21 || || Putative branched chain amino acid aminotransferase; regulated by Gcn4, Gcn2; induced in response to amino acid starvation (3-aminotriazole treatment); early-stage flow model biofilm formation || 1 -0.41 -0.67 -1.21 -1.56 -0.95 -1.18 0.78 0.20 0.92 -0.79 0.40 0.41 0.28 0.06 0.13 0.82
12218 || orf19.1613 || ILV2 || || Putative acetolactate synthase; regulated by Gcn4p; induced by amino acid starvation (3-AT treatment); stationary phase enriched protein || 1 -0.46 -0.39 -0.77 -0.37 -0.78 -0.51 0.92 0.51 0.91 0.20 0.08 0.32 -0.00 0.17 0.38 0.33
12219 || orf19.1613 || ILV2 || || Putative acetolactate synthase; regulated by Gcn4p; induced by amino acid starvation (3-AT treatment); stationary phase enriched protein || 1 -1.04 -1.12 -0.88 -0.25 -1.05 -0.84 0.86 0.44 1.00 0.15 0.16 0.20 -0.02 -0.31 0.36 -0.39
12220 || orf19.2781 || || || Protein with predicted serine/threonine kinase and tyrosine kinase domains; possibly an essential gene, disruptants not obtained by UAU1 method; Spider biofilm induced || 1 -0.97 -0.60 -1.91 -1.43 -0.79 -1.75 1.32 0.89 1.75 0.58 0.58 0.51 0.71 -0.54 -0.13 -0.90
12221 || orf19.6566 || || || Ortholog of C. dubliniensis CD36 : Cd36_71420, C. parapsilosis CDC317 : CPAR2_300980, Candida tenuis NRRL Y-1498 : CANTEDRAFT_94952 and Debaryomyces hansenii CBS767 : DEHA2A05346g || 1 -0.57 -0.61 -1.25 -0.36 0.04 -0.70 0.79 0.55 0.45 0.03 0.22 0.80 0.12 -0.07 0.20 -0.02
12222 || orf19.4625 || TOA2 || || Putative TFIIA small subunit; protein abundance decreased in CAI4 strain compared to the SC5314 strain, abundance not affected by reintegration of URA3 in CAI4; flucytosine induced; possibly an essential gene (UAU1 method) || 1 -0.37 -0.15 -0.84 -0.48 -0.32 -0.83 0.49 0.31 0.44 0.25 0.35 0.46 -0.20 -0.48 -0.06 0.31
12223 || orf19.7507 || || || Ortholog of C. dubliniensis CD36 : Cd36_25310, Pichia stipitis Pignal : PICST_30877, Candida tropicalis MYA-3404 : CTRG_01053 and Candida lusitaniae ATCC 42720 : CLUG_02644 || 1 -0.21 -0.19 -0.40 -0.22 -0.07 -0.73 0.42 0.49 0.17 0.02 0.42 0.37 -0.39 0.28 -0.20 0.50
12224 || orf19.394 || || || Putative kynureninase; predicted role in NAD biosynthesis; Hap43-repressed gene; flow model biofilm induced || 1 -0.26 -0.30 -0.53 -0.51 0.01 -0.51 0.49 0.51 0.53 -0.50 0.58 0.56 -0.70 0.10 -0.01 0.94
12225 || orf19.1033 || STR2 || || Ortholog(s) have cystathionine gamma-synthase activity, role in transsulfuration and cytosol, nucleus localization || 1 -0.16 0.26 -0.48 -0.71 -0.25 -0.80 0.76 0.57 0.88 -0.35 0.86 0.42 -0.43 0.27 -0.16 0.38
12226 || orf19.1033 || STR2 || || Ortholog(s) have cystathionine gamma-synthase activity, role in transsulfuration and cytosol, nucleus localization || 1 -0.12 -0.14 -0.59 -0.89 -0.64 -0.86 0.52 0.43 1.01 -0.28 0.58 0.51 -0.36 -0.08 -0.58 0.76
12227 || orf19.1108 || HAM1 || || Putative deoxyribonucleoside triphosphate pyrophosphohydrolase; caspofungin repressed; regulated by Gcn2p and Gcn4p || 1 -0.24 -0.07 -0.48 -0.62 -0.28 -0.09 1.04 0.64 0.74 -0.23 0.43 0.32 -0.29 0.00 -0.16 0.51
12228 || orf19.3115 || || || Protein of unknown function; rat catheter and Spider biofilm induced || 1 0.03 -0.04 -0.29 -0.25 -0.05 -0.32 1.04 0.59 1.01 0.10 0.41 0.28 -0.20 0.12 0.07 0.64
12229 || orf19.3114 || || || Predicted pseudouridine synthase; Spider biofilm induced || 1 -0.24 -0.36 -0.20 -1.02 -0.53 0.01 0.85 0.49 0.58 -0.29 0.10 0.44 -0.30 0.19 -0.38 0.59
12230 || orf19.7061 || || || Ortholog(s) have ATPase activity and cytosol, nucleus localization || 1 -0.27 -0.29 -0.56 -0.47 -0.61 -0.62 0.54 0.70 0.65 0.06 0.81 0.55 0.02 0.88 -0.34 0.41
12231 || orf19.7263 || || || Putative X-Pro aminopeptidase; Spider biofilm repressed || 1 -0.25 -0.10 -0.17 -0.18 -0.11 -0.11 0.43 0.39 0.08 -0.04 0.41 0.02 0.14 0.38 -0.10 0.14
12232 || orf19.2757 || || || Has domain(s) with predicted role in cell redox homeostasis || 1 0.06 -0.26 -0.87 -1.08 -0.05 -0.03 0.85 0.75 0.18 -0.15 0.89 0.50 0.55 0.55 -0.43 0.50
12233 || orf19.1034 || || || Protein with a predicted cytochrome b5-like Heme/Steroid binding domain; Hap43, caspofungin repressed; flow model biofilm induced || 1 -0.06 -0.04 -0.85 -1.79 -0.02 0.07 1.22 0.90 0.96 -1.09 1.44 0.69 0.90 0.60 -0.64 0.78
12234 || orf19.4617 || || || Predicted peptide alpha-N-acetyltransferase; flow model biofilm induced || 1 0.06 0.04 -1.16 -2.11 -0.73 -0.31 1.50 1.51 1.26 -0.58 1.54 0.78 0.07 0.50 -1.14 1.11
12235 || orf19.4617 || || || Predicted peptide alpha-N-acetyltransferase; flow model biofilm induced || 1 0.09 0.09 -1.49 -2.56 -0.83 -0.44 1.64 1.54 1.02 -0.83 1.53 0.44 0.04 -0.03 -1.28 0.93
12236 || orf19.7580 || || || Ortholog of C. dubliniensis CD36 : Cd36_35095, C. parapsilosis CDC317 : CPAR2_200710, Candida tenuis NRRL Y-1498 : CANTEDRAFT_112338 and Debaryomyces hansenii CBS767 : DEHA2G06094g || 1 0.06 0.17 -1.23 -1.66 -0.08 -0.47 0.89 0.89 -0.04 -0.52 1.25 0.17 0.21 0.27 -0.19 0.38
12237 || orf19.7580 || || || Ortholog of C. dubliniensis CD36 : Cd36_35095, C. parapsilosis CDC317 : CPAR2_200710, Candida tenuis NRRL Y-1498 : CANTEDRAFT_112338 and Debaryomyces hansenii CBS767 : DEHA2G06094g || 1 -0.11 -0.20 -1.18 -1.43 -0.16 -0.47 0.80 0.93 -0.22 -0.47 0.89 0.04 -0.12 -0.04 -0.32 0.47
12238 || orf19.3787 || || || Ortholog(s) have chromatin DNA binding activity and role in positive regulation of transcription from RNA polymerase II promoter, telomere maintenance, threonylcarbamoyladenosine metabolic process || 1 -0.04 -0.04 -0.53 -0.55 -0.33 -0.56 0.36 0.18 -0.26 0.02 0.54 0.23 -0.08 0.47 -0.22 0.52
12239 || orf19.4440 || SEC34 || || Ortholog(s) have role in CVT pathway, ER to Golgi vesicle-mediated transport, macroautophagy, peroxisome degradation, retrograde transport, vesicle recycling within Golgi and Golgi transport complex, cell division site localization || 1 -0.09 0.18 -0.45 -0.50 -0.38 -0.63 0.12 0.12 -0.19 -0.01 0.52 0.11 -0.04 0.30 -0.29 0.34
12240 || orf19.4437 || || || Ortholog(s) have ATPase activity, DNA binding, nucleosome binding, rDNA binding activity || 1 -0.12 0.01 -0.73 -0.72 -0.32 -1.28 0.34 0.67 -0.31 0.22 0.94 0.23 0.29 0.30 -0.68 0.37
12241 || orf19.6065 || || || RNA polymerase II holoenzyme/mediator subunit; regulated by Mig1, Tup1; amphotericin B, caspofungin repressed; protein present in exponential and stationary growth phase yeast; Hap43-repressed; Spider biofilm repressed || 1 -0.05 0.01 -0.55 -0.81 -0.76 -0.97 0.47 0.60 0.27 -0.58 0.95 0.58 0.42 0.29 -0.75 0.44
12242 || orf19.6065 || || || RNA polymerase II holoenzyme/mediator subunit; regulated by Mig1, Tup1; amphotericin B, caspofungin repressed; protein present in exponential and stationary growth phase yeast; Hap43-repressed; Spider biofilm repressed || 1 -0.25 -0.33 -0.97 -1.18 -1.52 -1.27 0.31 0.57 0.12 -0.38 0.89 0.56 0.13 0.41 -1.13 0.71
12243 || orf19.5136 || || || Putative pyridoxamine 5'-phosphate oxidase; planktonic growth and early-stage flow model biofilm induced || 1 -0.31 -0.19 -1.03 -1.29 -0.94 -0.76 0.19 0.20 0.03 -0.69 0.44 -0.31 0.05 0.44 -1.24 0.91
12244 || orf19.6559 || || || RNA polymerase III transcription initiation factor complex (TFIIIC) subunit; growth phase regulated protein; downregulaated in stationary phase yeast cultures; Hap43-repressed; flow model biofilm induced; Spider biofilm repressed || 1 -0.64 -0.67 -1.71 -2.04 -1.28 -1.19 1.31 0.98 0.52 -1.06 1.13 -0.12 0.59 0.90 -1.31 0.84
12245 || orf19.3391 || ADK1 || || Putative adenylate kinase; repressed in hyphae; macrophage-induced protein; adenylate kinase release used as marker for cell lysis; possibly essential (UAU1 method); flow model biofilm induced; rat catheter and Spider biofilm repressed || 1 -0.27 -0.27 -1.38 -1.25 -0.56 -0.80 0.77 0.96 -0.19 -0.29 0.95 -0.14 0.68 0.29 -0.86 0.55
12246 || orf19.3391 || ADK1 || || Putative adenylate kinase; repressed in hyphae; macrophage-induced protein; adenylate kinase release used as marker for cell lysis; possibly essential (UAU1 method); flow model biofilm induced; rat catheter and Spider biofilm repressed || 1 -0.50 -0.60 -1.47 -1.52 -1.08 -1.09 0.59 0.61 -0.55 -0.44 0.58 -0.36 0.23 0.03 -1.08 0.49
12247 || orf19.2381 || || || Protein of unknown function; possibly an essential gene, disruptants not obtained by UAU1 method || 1 -0.30 -0.27 -0.75 -1.14 -1.38 -0.93 0.68 0.57 0.38 -0.36 0.76 0.34 0.79 0.28 -0.12 0.55
12248 || orf19.4528 || || || Ortholog(s) have role in vacuolar protein processing and endoplasmic reticulum localization || 1 -0.47 0.08 -0.64 -0.62 -1.36 -1.27 0.66 0.55 0.31 -0.08 0.33 0.12 0.71 0.13 -0.03 0.18
12249 || orf19.4013 || || || Putative protein of unknown function; Hap43p-repressed gene; S. cerevisiae ortholog YHR045W localizes to the endoplasmic reticulum || 1 0.11 0.19 -0.39 -0.85 -0.77 -0.86 0.66 0.60 0.53 -0.57 0.33 0.01 0.92 0.63 -0.86 0.36
12250 || orf19.4939 || MON2 || || Peripheral membrane protein; role in endocytosis and vacuole integrity; flow model and rat catheter biofilm repressed || 1 0.14 0.38 -0.15 -0.49 -0.53 -1.13 0.42 0.46 0.17 -0.17 0.33 0.21 0.23 0.60 -0.40 0.52
12251 || orf19.5505 || HIS7 || || Putative imidazole glycerol phosphate synthase; histidine biosynthesis; no human/murine homolog; transcription induced by histidine starvation; regulated by Gcn2p and Gcn4p; higher protein level in stationary phase || 1 -0.30 -0.17 -1.12 -1.32 0.35 -1.01 0.63 0.16 0.82 -0.28 0.38 0.48 0.12 0.28 0.01 0.58
12252 || orf19.6740 || || || Ortholog(s) have ubiquitin-protein ligase activity and role in generation of catalytic spliceosome for first transesterification step || 1 -0.17 -0.31 -0.56 -0.77 0.03 -0.47 0.19 0.79 -0.36 -0.03 0.84 -0.14 -0.19 0.19 -0.30 0.14
12253 || orf19.5104 || LTP1 || || Putative protein phosphatase of the PTP family (tyrosine-specific), similar to S. cerevisiae Ltp1p || 1 -0.13 -0.27 -0.52 -0.60 0.06 -0.15 0.30 0.61 -0.01 -0.24 0.46 0.16 0.12 0.02 -0.08 -0.19
12254 || orf19.4491 || ERG20 || || Putative farnesyl pyrophosphate synthetase involved in isoprenoid and sterol biosynthesis, based on similarity to S. cerevisiae Erg20p; likely to be essential for growth, based on an insertional mutagenesis strategy || 1 -0.34 -0.67 -0.75 -0.52 -0.31 -0.32 0.23 0.93 -0.06 -0.16 0.80 0.64 -0.03 -0.02 -0.56 0.05
12255 || orf19.6309 || MSS11 || || Transcription factor; activator that binds to Flo8 via a LisH motif to cooperatively activate transcription of hypha-specific genes; required for hyphal growth || 1 -0.63 -0.67 -0.41 -0.28 0.01 -0.37 0.25 0.42 0.10 -0.05 0.88 0.00 0.25 -0.04 -0.15 0.04
12256 || orf19.7102 || || || Has domain(s) with predicted exonuclease activity, nucleic acid binding activity and intracellular localization || 1 -0.55 -0.45 -0.36 -1.00 -0.43 -0.76 0.73 0.67 -0.05 0.39 1.13 0.61 -0.24 0.29 -0.46 0.68
12257 || orf19.1248 || || || Putative RNA polymerase II subunit B44; heterozygous null mutant exhibits resistance to parnafungin in the C. albicans fitness test; Spider biofilm repressed || 1 -0.33 -0.09 -0.27 -0.13 -0.27 -0.72 0.03 0.52 0.08 0.43 0.69 0.39 -0.11 0.07 -0.09 0.31
12258 || orf19.4112 || || || Ortholog(s) have 8-oxo-dGDP phosphatase activity, ATP binding, magnesium ion binding, thiamine binding, thiamine diphosphokinase activity, role in thiamine biosynthetic process and cytosol localization || 1 -0.39 -0.19 -0.35 -0.04 -0.77 -0.46 0.03 0.55 0.31 0.53 0.32 0.13 -0.37 0.35 0.04 0.13
12259 || orf19.3787 || || || Ortholog(s) have chromatin DNA binding activity and role in positive regulation of transcription from RNA polymerase II promoter, telomere maintenance, threonylcarbamoyladenosine metabolic process || 1 -0.16 -0.32 -0.21 -0.13 -0.50 -0.29 -0.11 0.53 0.19 0.50 0.54 0.27 -0.28 0.63 -0.39 0.48
12260 || orf19.7185 || || || Ortholog of C. dubliniensis CD36 : Cd36_73630, C. parapsilosis CDC317 : CPAR2_805330, Candida tenuis NRRL Y-1498 : CANTEDRAFT_119330 and Debaryomyces hansenii CBS767 : DEHA2G16544g || 1 -0.44 -0.47 -0.63 -0.45 -0.45 -0.14 0.10 0.50 0.29 0.25 0.27 0.50 -0.06 0.35 -0.22 0.15
12261 || orf19.752 || || || Has domain(s) with predicted methyltransferase activity and role in metabolic process || 1 -0.24 -0.25 -0.62 -0.80 -0.45 -0.65 0.73 1.18 0.54 0.52 0.22 0.05 -0.62 0.57 -0.17 0.30
12262 || orf19.1768 || || || Ortholog of C. parapsilosis CDC317 : CPAR2_407480, C. dubliniensis CD36 : Cd36_24170, Candida orthopsilosis Co 90-125 : CORT_0C06830 and Spathaspora passalidarum NRRL Y-27907 : SPAPADRAFT_65786 || 1 -0.20 0.06 -0.58 -1.18 -0.40 -0.17 0.41 1.52 0.52 0.54 0.42 -0.13 -0.09 0.66 -0.15 0.71
12263 || orf19.5017 || DUR32 || || Putative urea transporter; possibly an essential gene, disruptants not obtained by UAU1 method || 1 -0.43 -0.76 -0.72 -0.53 -0.61 0.14 -0.43 0.43 0.06 0.30 -0.25 0.57 -0.60 0.46 0.07 0.81
12264 || orf19.6411 || || || Protein similar to S. cerevisiae Vac14p; a protein involved in regulated synthesis of PtdIns(3,5)P(2); transposon mutation affects filamentous growth || 1 -0.26 -0.18 -0.15 -0.24 -0.37 -0.12 -0.05 -0.13 0.34 0.02 0.02 0.27 -0.58 0.25 -0.17 0.56
12265 || orf19.2915 || || || Ortholog(s) have ATPase activity, GTPase activity, adenosine-diphosphatase activity, cytidine diphosphatase activity, guanosine-diphosphatase activity, nucleoside-triphosphate diphosphatase activity, uridine-diphosphatase activity || 1 -0.05 -0.17 -0.25 -0.26 -0.15 -0.12 0.04 -0.03 0.18 -0.02 -0.16 0.09 -0.42 0.12 0.09 0.35
12266 || orf19.6437 || CDC23 || || Similar to anaphase-promoting complex component; possibly transcriptionally regulated by Tac1p || 1 0.13 -0.06 -0.39 -0.26 -0.35 -0.26 -0.12 -0.09 0.06 -0.17 -0.12 0.26 -0.47 0.25 0.08 0.64
12267 || orf19.4897 || SFH5 || || Putative phosphatidylinositol transporter; rat catheter and Spider biofilm repressed || 1 -0.28 -0.25 -1.14 -0.70 -0.64 -0.40 -0.09 0.15 -0.37 -0.25 0.09 -0.17 -0.81 0.16 -0.32 0.66
12268 || orf19.1178 || || || Putative transcription factor with bZIP DNA-binding motif; Hap43p-repressed gene || 1 -0.05 -0.44 -0.30 -0.27 -0.28 -0.48 -0.02 0.03 -0.25 -0.26 0.15 0.13 -0.78 0.38 -0.41 0.43
12269 || orf19.317 || PNP1 || || Purine nucleoside phosphorylase; metabolizes inosine and guanosine nucleosides; in the nicotinamide riboside salvage pathway; Spider biofilm repressed || 1 -0.20 -0.14 -0.05 -0.25 -0.25 -0.12 -0.13 -0.10 -0.08 -0.14 0.03 0.02 -0.67 0.27 -0.20 0.15
12270 || orf19.4247 || || || Protein of unknown function; rat catheter and Spider biofilm repressed || 1 -0.48 -0.46 -0.39 -0.49 -0.45 -0.32 -0.10 0.33 0.14 -0.08 0.10 -0.05 -1.23 -0.08 -0.32 0.47
12271 || orf19.5101 || CCR4 || || Component of the Ccr4-Pop2 mRNA deadenylase; transposon mutation affects filamentous growth || 1 -0.48 -0.35 -0.48 -0.17 -0.22 -0.02 -0.19 -0.18 -0.17 -0.10 -0.04 0.12 -0.47 -0.43 0.11 0.49
12272 || orf19.1387 || || || Ortholog(s) have 4 iron, 4 sulfur cluster binding activity, role in iron-sulfur cluster assembly, tRNA wobble uridine modification and cytoplasm localization || 1 -0.34 -0.56 -0.46 -0.36 -0.26 -0.01 -0.22 -0.17 -0.29 -0.40 0.05 0.08 -0.85 -0.05 0.12 0.55
12273 || orf19.7410 || CYM1 || || Putative metalloprotease of the mitochondrial intermembrane space; rat catheter biofilm induced || 1 -0.45 -0.41 -0.32 -0.20 -0.40 -0.25 -0.13 -0.19 -0.27 0.05 0.14 0.48 -0.99 -0.10 0.13 0.46
12274 || orf19.4182 || || || Ortholog(s) have role in response to drug and mitochondrion localization || 1 -0.23 -0.22 -0.53 -0.35 -0.36 -0.47 -0.13 -0.19 -0.01 0.07 -0.02 0.19 -1.20 -0.07 -0.01 0.28
12275 || orf19.3980 || || || Ortholog(s) have role in cytoplasmic translation, regulation of translation and cytosol, polysomal ribosome localization || 1 -0.45 -0.43 -0.71 -0.33 -0.29 -0.35 -0.22 -0.27 -0.14 -0.07 -0.09 0.35 -0.70 -0.03 0.15 0.10
12276 || orf19.1493 || RAD7 || || Protein similar to S. cerevisiae Rad7p, which is a subunit of the Nucleotide Excision Repair Factor 4; induced under hydroxyurea treatment || 1 -0.87 -0.80 -0.92 -1.02 -0.88 -0.55 -0.46 -0.35 -0.07 0.05 0.20 0.68 -1.00 0.24 0.17 0.16
12277 || orf19.6821 || || || Ortholog(s) have ubiquitin-protein ligase activity || 1 -0.74 -0.77 -0.63 -0.73 -0.47 -0.44 -0.35 -0.26 0.01 -0.15 -0.01 0.59 -0.60 0.24 -0.10 0.61
12278 || orf19.7206 || OCA6 || || Putative protein phosphatase of the PTP family (tyrosine-specific), similar to S. cerevisiae Oca6p; mutant shows virulence defect || 1 -0.50 -0.47 -0.35 -0.49 -0.46 -0.53 -0.16 -0.09 -0.13 -0.15 -0.24 0.31 -0.55 0.05 0.18 0.53
12279 || orf19.4735 || || || Ornithine cyclodeaminase family protein; Sef1, Sfu1, and Hap43-regulated; ortholog of S. cerevisiae YGL159W and S. pombe SPAP11E10.01; rat catheter biofilm induced || 1 -0.58 -0.83 -0.66 -0.40 -0.44 -0.35 -0.05 0.14 0.13 -0.06 -0.34 0.42 -0.71 0.32 0.31 0.31
12280 || orf19.7286 || RPN7 || || Subunit of the proteasome regulatory particle; regulated by Gcn2p and Gcn4p; protein present in exponential and stationary growth phase yeast cultures || 1 -0.50 -0.50 -0.58 -0.61 -0.36 -0.36 -0.13 0.05 -0.40 0.11 0.09 0.30 -0.74 0.17 0.50 0.68
12281 || orf19.2933 || || || Ortholog(s) have ubiquitin-specific protease activity, role in protein deubiquitination, regulation of transcription, DNA-dependent and cytosol, nucleus localization || 1 -0.42 -0.41 -0.49 -0.36 -0.25 0.18 -0.29 -0.40 -0.17 0.15 0.05 0.57 -0.66 0.19 0.17 0.22
12282 || orf19.4472 || || || Ortholog of Candida albicans WO-1 : CAWG_00996 || 1 -0.45 -0.75 -1.29 -0.08 -0.50 -0.83 -0.62 -0.38 -0.34 -0.16 -0.21 0.32 -0.73 0.28 -0.41 0.43
12283 || orf19.2929 || GSC1 || || Essential beta-1,3-glucan synthase subunit; gsc1 allele determines resistance/sensitivity to echinocandins; 16 predicted membrane-spanning regions; mRNA abundance declines after yeast-to-hypha transition; Spider biofilm induced || 1 -0.84 -0.89 -0.62 -0.15 -0.37 -0.51 -0.35 0.24 -0.64 -0.14 0.32 0.03 -0.45 -0.23 0.13 0.03
12284 || orf19.3166 || || || Ortholog(s) have role in Golgi to endosome transport, cell morphogenesis, cleistothecium development, conidium formation and endoplasmic reticulum organization, more || 1 -0.18 -0.37 0.03 -0.15 -0.24 -0.52 -0.40 -0.16 -0.10 0.01 -0.12 0.12 -0.70 0.14 -0.41 0.39
12285 || orf19.3512 || CSP1 || || Putative cell wall associated protein; gene only found in C. albicans and C. dubliniensis; highly upregulated during chlamydospore development in both species; localized to chlamydospore cell wall || 1 -0.63 -0.67 -0.38 -0.62 -0.37 -0.69 -0.67 -0.36 0.29 -0.01 -0.18 0.42 -0.93 0.05 -0.69 0.54
12286 || orf19.2352 || || || Ortholog(s) have mitochondrion localization || 1 -0.11 -0.14 -0.09 -0.22 -0.09 -0.32 -0.17 0.01 0.01 0.05 0.04 0.16 -0.34 -0.18 -0.35 0.09
12287 || orf19.7491 || RTT109 || || Histone acetyltransferase, mutants are sensitive to DNA damage, show decreased virulence in mice, decreased white-to-opaque switching and increased susceptibility to killing by macrophages || 1 -0.49 -0.26 -0.56 -0.61 -0.53 -0.85 -0.35 -0.00 0.04 0.15 -0.10 0.56 -0.35 -0.13 -0.62 0.15
12288 || orf19.7224 || || || Ortholog(s) have ubiquitin-protein ligase activity and role in histone catabolic process, histone ubiquitination || 1 -0.57 -0.58 -0.56 -0.37 -0.85 -0.75 -0.00 -0.19 0.24 0.22 0.11 0.31 -0.52 0.01 -0.46 0.28
12289 || orf19.7566 || || || Predicted amino acid transport domain; transcript upregulated in clinical strains from HIV+ patients with oral candidiasis; alkaline upregulated by Rim101; rat catheter, Spider and flow model biofilm induced || 1 -0.87 -0.68 -0.69 -0.80 -0.78 -1.02 0.12 -0.70 0.64 0.26 -0.09 0.36 -0.64 0.12 -0.64 0.39
12290 || orf19.4182 || || || Ortholog(s) have role in response to drug and mitochondrion localization || 1 -0.37 -0.39 -0.28 -0.37 -0.41 -0.66 -0.16 -0.45 0.25 0.11 -0.13 -0.24 -0.84 -0.18 -0.25 0.00
12291 || orf19.5165 || || || Ortholog(s) have cytoplasm localization || 1 -0.18 -0.99 -0.44 -0.34 -0.67 -0.40 -0.24 -0.26 -0.02 -0.00 -0.28 0.22 -0.60 -0.11 -0.20 0.19
12292 || orf19.2407 || DPS1-1 || || Putative tRNA-Asp synthetase; genes encoding ribosomal subunits, translation factors, tRNA synthetases are downregulated upon phagocytosis by murine macrophage; protein enriched in stationary phase yeast cultures || 1 -0.37 -0.29 -0.40 -0.09 -0.12 -0.41 0.13 -0.03 0.04 0.07 0.00 0.15 -0.25 -0.03 0.18 0.08
12293 || orf19.4735 || || || Ornithine cyclodeaminase family protein; Sef1, Sfu1, and Hap43-regulated; ortholog of S. cerevisiae YGL159W and S. pombe SPAP11E10.01; rat catheter biofilm induced || 1 -0.92 -0.86 -0.89 -0.70 -0.38 -0.59 0.06 -0.12 0.16 0.03 -0.30 0.13 -0.65 0.11 0.43 0.17
12294 || orf19.441 || RPT1 || || Putative 26S proteasome regulatory subunit 7; Hap43p-repressed gene; regulated by Gcn2p and Gcn4p; overlaps orf19.442 || 1 -0.56 -0.61 -0.62 -0.47 -0.39 -0.39 -0.17 -0.17 -0.06 0.04 -0.11 0.20 -0.37 -0.09 0.32 0.07
12295 || orf19.610 || EFG1 || || bHLH transcription factor; required for white-phase cell type, RPMI and Spider biofilm formation, hyphal growth, cell-wall gene regulation; roles in adhesion, virulence; Cph1 and Efg1 have role in host cytokine response; binds E-box || 1 -0.85 -0.91 -1.08 -0.31 -0.20 -0.62 -0.39 -0.19 -0.16 -0.01 -0.07 0.22 -0.71 -0.20 0.72 -0.14
12296 || orf19.2676 || || || Predicted hexameric RecA-like ATPase Elp456 Elongator subcomplex subunit; required for modification of wobble nucleosides in tRNA; Spider biofilm induced || 1 -0.58 -0.92 -1.05 -0.37 -0.47 -1.04 -0.35 -0.08 0.23 0.30 -0.03 0.06 -0.58 -0.25 0.36 -0.26
12297 || orf19.3293 || || || Putative enoyl reductase involved in very long chain fatty acid elongation; possibly an essential gene, disruptants not obtained by UAU1 method || 1 -1.11 -1.19 -0.80 -0.66 -0.79 -0.87 -0.38 -0.06 -0.04 0.58 -0.06 -0.12 -0.86 -0.17 0.09 -0.61
12298 || orf19.7080 || LEU2 || || Isopropyl malate dehydrogenase; leucine biosynthesis; induced by human whole blood or PMNs; protein level decreases in stationary phase; GlcNAc-induced protein; flow model biofilm repressed || 1 -1.90 -2.01 -1.10 -0.64 -1.38 -1.46 -0.05 0.08 -0.27 0.17 -0.34 -0.42 -1.35 -0.32 0.22 -0.75
12299 || orf19.7080 || LEU2 || || Isopropyl malate dehydrogenase; leucine biosynthesis; induced by human whole blood or PMNs; protein level decreases in stationary phase; GlcNAc-induced protein; flow model biofilm repressed || 1 -1.40 -1.44 -0.88 -0.34 -1.12 -1.42 0.13 0.14 -0.21 0.28 -0.20 -0.20 -1.32 -0.09 0.35 -0.27
12300 || orf19.7080 || LEU2 || || Isopropyl malate dehydrogenase; leucine biosynthesis; induced by human whole blood or PMNs; protein level decreases in stationary phase; GlcNAc-induced protein; flow model biofilm repressed || 1 -1.90 -1.84 -1.05 -0.28 -1.30 -1.28 0.06 0.13 -0.19 0.26 -0.28 -0.30 -1.30 -0.28 0.19 -0.00
12301 || orf19.7080 || LEU2 || || Isopropyl malate dehydrogenase; leucine biosynthesis; induced by human whole blood or PMNs; protein level decreases in stationary phase; GlcNAc-induced protein; flow model biofilm repressed || 1 -1.55 -1.53 -1.18 -0.73 -1.09 -1.17 0.11 0.03 -0.13 0.23 -0.27 -0.05 -1.03 0.08 0.25 -0.06
12302 || orf19.2510 || || || Ortholog(s) have role in protein folding, tubulin complex assembly || 1 -0.26 -0.31 -0.51 -0.58 -0.25 -0.62 -0.02 -0.13 -0.19 -0.40 0.24 0.05 0.19 0.31 -0.19 0.34
12303 || orf19.6952 || || || Ortholog(s) have DNA binding, chromatin binding, histone deacetylase activity || 1 -0.55 -0.39 -0.72 -0.61 -0.82 -0.88 -0.08 -0.33 -0.62 -0.81 0.12 0.14 0.11 0.29 -0.17 0.52
12304 || orf19.3437 || || || Has domain(s) with predicted serine-type endopeptidase activity and role in proteolysis || 1 -0.35 -0.60 -0.51 -0.71 -0.43 -0.90 -0.36 -0.10 -0.57 -0.53 0.19 -0.17 -0.17 0.02 0.17 0.40
12305 || orf19.4116 || || || Ortholog(s) have N-acetyltransferase activity, role in response to drug and nuclear envelope, plasma membrane localization || 1 -0.71 -0.87 -0.59 -1.26 -1.25 -0.75 -0.36 -0.17 -0.23 -0.56 -0.35 0.12 -0.58 0.02 0.16 0.13
12306 || orf19.931 || || || Ortholog of Candida albicans WO-1 : CAWG_04452 || 1 -0.69 -0.65 -0.67 -0.79 -0.72 -0.67 -0.07 -0.47 -0.26 -1.00 -0.29 0.04 -0.49 0.15 -0.12 -0.16
12307 || orf19.7586 || CHT3 || || Major chitinase; secreted; functional homolog of S. cerevisiae Cts1p; 4 N-glycosylation motifs; possible O-mannosylation; putative signal peptide; hyphal-repressed; farnesol upregulated in biofilm; regulated by Efg1p, Cyr1p, Ras1p || 1 -1.58 -1.66 -1.81 -1.15 -3.80 -1.46 -0.61 -0.84 -1.27 -1.85 -0.17 -0.58 -0.46 -0.30 -0.38 -0.25
12308 || orf19.97 || CAN1 || || Basic amino acid permease; complements lysine transport mutation; 10 predicted transmembrane regions, 3 predicted N-glycosylation sites; phagocytosis by macrophages induces transcript; rat catheter, Spider and flow model biofilm induced || 1 -1.49 -1.59 -1.54 -1.30 -2.04 -1.66 -0.05 -1.70 -1.38 -1.98 -0.14 0.38 -0.73 -0.89 -1.15 1.13
12309 || orf19.5663 || RCH1 || || Plasma membrane protein; involved in regulation of cytosolic calcium homeostasis; null mutation confers sensitivity to calcium and resistance to azoles and terbinafine; rat catheter biofilm induced || 1 -1.33 -1.42 -1.50 -1.35 -1.71 -1.27 0.07 -0.89 -0.72 -0.74 -0.26 -0.15 0.34 0.41 -0.20 0.98
12310 || orf19.5663 || RCH1 || || Plasma membrane protein; involved in regulation of cytosolic calcium homeostasis; null mutation confers sensitivity to calcium and resistance to azoles and terbinafine; rat catheter biofilm induced || 1 -1.22 -1.42 -0.95 -0.69 -2.02 -1.62 -0.05 -0.74 -0.43 -0.62 -0.22 -0.19 0.56 -0.10 -0.66 0.68
12311 || orf19.5917 || STP3 || || Transcription factor; regulates SAP2, OPT1 expression and thereby protein catabolism for nitrogen source; activated via amino-acid-induced proteolytic processing; macrophage/pseudohyphal-repressed; Spider biofilm repressed || 1 -1.13 -1.15 -1.03 -0.73 -2.12 -1.69 0.11 -0.48 0.03 -0.73 -0.44 0.29 0.46 -0.90 -0.88 0.85
12312 || orf19.5917 || STP3 || || Transcription factor; regulates SAP2, OPT1 expression and thereby protein catabolism for nitrogen source; activated via amino-acid-induced proteolytic processing; macrophage/pseudohyphal-repressed; Spider biofilm repressed || 1 -1.20 -1.41 -1.64 -1.18 -2.11 -1.86 0.14 -0.37 -0.22 -0.71 -0.25 0.37 0.19 -0.42 -0.32 0.90
12313 || orf19.2494 || || || Ortholog(s) have glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity, role in glutaminyl-tRNAGln biosynthesis via transamidation, mitochondrial translation and glutamyl-tRNA(Gln) amidotransferase complex, mitochondrion localization || 1 -0.73 -0.87 -0.67 -0.80 -0.06 -0.71 -0.00 -0.18 -0.28 -0.21 -0.34 -0.16 0.09 0.09 -0.28 -0.21
12314 || orf19.2065 || || || Ortholog(s) have role in allantoin catabolic process and cytosol, nucleus localization || 1 -1.16 -1.40 -1.23 -0.75 -0.44 -0.70 0.76 0.09 -0.19 -0.30 -0.47 -0.52 -0.16 0.38 -0.73 -0.06
12315 || orf19.1654 || || || Predicted membrane protein; induced by prostaglandins || 1 -0.43 -0.61 -1.26 -1.42 -0.68 -0.80 0.51 -0.02 -0.09 -0.87 0.06 -0.40 0.39 0.65 -0.43 0.16
12316 || orf19.6977 || GPI1 || || Putative protein of GPI synthesis; expression is reduced in a fluconazole-resistant isolate || 1 -0.73 -0.28 -1.07 -1.53 -1.02 -1.05 0.22 -0.13 -0.14 -0.44 -0.28 -0.28 0.36 0.42 -0.79 0.25
12317 || orf19.4784 || CRP1 || || Copper transporter; CPx P1-type ATPase; mediates Cu resistance; similar to Menkes and Wilson disease proteins; copper-induced; Tbf1-activated; suppresses Cu sensitivity of S. cerevisiae cup1 mutant; flow model biofilm induced || 1 -1.60 -1.63 -2.45 -3.11 -1.13 -1.98 -0.51 -0.34 0.24 -1.01 -0.10 -0.88 0.79 0.96 -0.87 0.43
12318 || orf19.103 || KAR5 || || Ortholog of S. cerevisiae Kar5; involved in nuclear membrane fusion during karyogamy; induced by alpha factor || 1 -1.15 -1.28 -1.69 -2.32 -0.27 -1.22 -0.05 -0.45 -0.12 -0.55 -0.05 -0.56 -0.28 0.18 -0.52 -0.26
12319 || orf19.949 || || || Ortholog of C. dubliniensis CD36 : Cd36_50420, C. parapsilosis CDC317 : CPAR2_304100, Candida tenuis NRRL Y-1498 : CANTEDRAFT_98299 and Debaryomyces hansenii CBS767 : DEHA2B07634g || 1 -0.43 -0.49 -1.32 -0.96 -0.18 -0.54 -0.21 -0.19 -0.70 -0.40 -0.05 -0.19 -0.09 0.44 -0.28 -0.35
12320 || orf19.2060 || SOD5 || || Cu and Zn-containing superoxide dismutase; protects against oxidative stress; induced by neutrophils, hyphal growth, caspofungin, osmotic/oxidative stress; oralpharyngeal candidiasis induced; rat catheter and Spider biofilm induced || 1 -1.01 -1.04 -2.19 -1.66 -0.58 -0.69 -0.60 -0.50 -0.85 -0.51 -0.17 -0.56 -0.69 0.30 -0.44 0.69
12321 || orf19.2964 || || || Ortholog(s) have DNA translocase activity || 1 -0.44 -0.29 -1.11 -0.92 -0.69 -1.00 -0.26 -0.46 -0.68 -0.30 -0.01 -0.26 0.38 0.03 -0.51 -0.07
12322 || orf19.5382 || || || Ortholog of Candida albicans WO-1 : CAWG_02410 || 1 -0.43 -0.65 -0.65 -0.45 -0.06 0.14 -0.17 -0.16 -0.26 0.27 0.09 0.04 0.38 0.13 0.11 0.19
12323 || orf19.5382 || || || Ortholog of Candida albicans WO-1 : CAWG_02410 || 1 -0.53 -0.80 -0.59 -0.58 -0.18 0.08 -0.01 -0.07 -0.31 0.13 0.12 0.25 0.24 0.15 0.06 0.31
12324 || orf19.5382 || || || Ortholog of Candida albicans WO-1 : CAWG_02410 || 1 -0.56 -0.89 -0.68 -0.63 -0.19 0.04 -0.14 -0.06 -0.26 0.15 0.19 0.10 0.17 0.04 -0.05 0.31
12325 || orf19.5382 || || || Ortholog of Candida albicans WO-1 : CAWG_02410 || 1 -0.64 -0.71 -0.83 -0.62 -0.31 0.04 -0.19 -0.07 -0.36 0.11 0.10 0.10 0.15 0.01 0.12 0.42
12326 || orf19.2102 || CKB1 || || Regulatory subunit of protein kinase CK2 (casein kinase II), beta subunit; null mutants are hypersensitive to caspofungin and hydrogen peroxide medium || 1 -0.87 -0.73 -0.63 -0.63 -0.55 -0.02 -0.05 -0.03 -0.28 0.29 0.40 0.25 -0.02 -0.02 0.00 0.24
12327 || orf19.826 || MED1 || || RNA polymerase II mediator complex subunit; RNA polymerase II transcription cofactor || 1 -1.04 -1.09 -0.71 -0.59 -0.52 -0.45 -0.42 -0.21 0.01 0.09 0.23 0.60 0.06 0.28 0.20 0.50
12328 || orf19.1760 || RAS1 || || RAS signal transduction GTPase; regulates cAMP and MAP kinase pathways; role in hyphal induction, virulence, apoptosis, heat-shock sensitivity; nonessential; plasma membrane-localized; complements viability of S. cerevisiae ras1 ras2 mutant || 1 -1.07 -1.15 -0.77 -0.48 -0.59 -0.05 -0.36 -0.46 -0.23 -0.03 -0.34 0.32 0.11 0.07 0.34 0.31
12329 || orf19.5377 || HOS2 || || Putative histone deacetylase; mutations affect filamentous growth; genetic evidence suggests that Set3p and Hos2p function together as a complex involved in regulation of white-opaque switching, morphogenesis, and virulence || 1 -0.94 -0.91 -0.54 -0.88 -0.47 -0.17 -0.53 -0.52 -0.39 -0.12 0.03 0.50 -0.06 0.23 0.17 0.13
12330 || orf19.2408 || || || Ortholog(s) have tRNA methyltransferase activity, role in tRNA methylation, wybutosine biosynthetic process and cytosol, nucleus localization || 1 -0.94 -0.73 -0.24 -0.85 -0.27 0.19 -0.16 -0.31 -0.25 -0.04 0.07 0.33 -0.19 -0.04 0.29 0.12
12331 || orf19.4278 || || || Ortholog(s) have methylated histone residue binding activity and role in negative regulation of transcription from RNA polymerase II promoter || 1 -0.84 -0.74 -0.44 -0.55 -0.91 -0.56 -0.43 -0.12 -0.51 -0.36 0.07 0.24 0.17 0.12 0.21 -0.08
12332 || orf19.2204.2 || RHO2 || || Ortholog(s) have GTPase activity || 1 -1.00 -1.20 -0.87 -0.69 -1.23 -1.01 -0.05 -0.15 -0.37 -0.04 -0.42 0.18 -0.01 0.22 0.15 0.08
12333 || orf19.6029 || ROT1 || || Similar to S. cerevisiae Rot1p, which is involved in cell wall 1,6-beta-glucan biosynthesis; has predicted transmembrane region; possibly an essential gene, disruptants not obtained by UAU1 method || 1 -0.91 -1.32 -0.94 -0.91 -1.17 -0.76 -0.25 -0.04 -0.31 0.09 0.14 0.31 0.37 0.59 0.01 -0.12
12334 || orf19.7363 || KRE6 || || Essential beta-1,6-glucan synthase subunit; change in mRNA length, not abundance, at yeast-hypha transition; alkaline induced by Rim101, on cell wall regeneration; Spider biofilm induced; Bcr1-repressed in RPMI a/a biofilms || 1 -1.19 -1.52 -0.97 -0.94 -1.01 -0.71 -0.00 -0.43 -0.25 -0.10 -0.14 0.16 0.20 0.44 -0.37 -0.16
12335 || orf19.7362 || SKN1 || || Protein with a role in beta-1,6-glucan synthesis; probable N-glycosylated type II membrane protein; transcript and mRNA length change induced by yeast-hypha transition; induced by Rim101, caspofungin; rat catheter and Spider biofilm induced || 1 -1.02 -1.31 -0.97 -0.69 -0.71 -0.46 0.01 -0.37 -0.67 -0.41 -0.04 0.09 0.24 0.33 -0.45 -0.12
12336 || orf19.1139 || || || Protein of unknown funtion; S. cerevisiae ortholog Svl3 plays a role in endocytosis and is localized to the bud neck; Spider biofilm induced || 1 -1.01 -0.98 -1.25 -0.91 -0.80 -0.42 -0.34 -0.68 -0.53 -0.01 0.02 0.37 0.21 0.14 0.23 -0.14
12337 || orf19.1139 || || || Protein of unknown funtion; S. cerevisiae ortholog Svl3 plays a role in endocytosis and is localized to the bud neck; Spider biofilm induced || 1 -0.96 -1.13 -0.89 -0.90 -1.03 -0.78 -0.36 -0.79 -0.37 -0.13 0.24 0.47 -0.04 -0.18 0.04 -0.36
12338 || orf19.581 || || || Putative RNA-binding protein; transcript is upregulated in an RHE model of oral candidiasis || 1 -0.75 -0.73 -1.23 -1.16 -0.83 -0.42 -0.29 -0.56 -0.49 -0.16 -0.04 0.30 0.42 0.19 -0.02 0.41
12339 || orf19.3476 || HRR25 || || Predicted protein serine/threonine kinase; Spider biofilm induced || 1 -0.77 -0.82 -1.16 -1.02 -0.57 -0.23 0.31 -0.21 -0.15 -0.21 0.03 0.22 0.57 0.45 0.13 0.12
12340 || orf19.2494 || || || Ortholog(s) have glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity, role in glutaminyl-tRNAGln biosynthesis via transamidation, mitochondrial translation and glutamyl-tRNA(Gln) amidotransferase complex, mitochondrion localization || 1 -0.79 -0.92 -1.06 -1.11 -0.65 -0.53 0.28 -0.02 0.15 0.09 -0.03 0.19 -0.01 0.69 0.09 0.10
12341 || orf19.551 || || || Ortholog of C. dubliniensis CD36 : Cd36_29980, C. parapsilosis CDC317 : CPAR2_204170, Candida tenuis NRRL Y-1498 : CANTEDRAFT_110235 and Debaryomyces hansenii CBS767 : DEHA2F17072g || 1 -1.01 -1.18 -1.41 -2.21 -1.04 -0.66 0.18 -0.42 -0.28 0.26 -0.13 -0.01 0.21 0.84 -0.35 0.07
12342 || orf19.6769 || || || Ortholog(s) have cytoplasm localization || 1 -1.30 -1.33 -1.89 -2.21 -1.43 -1.00 0.40 -0.92 -0.45 0.26 0.39 -0.08 0.79 0.17 0.31 0.20
12343 || orf19.985 || || || Ortholog(s) have endoplasmic reticulum, ribosome localization || 1 -1.28 -1.11 -2.03 -1.85 -0.99 -0.95 0.36 -0.10 -0.03 0.25 0.20 0.41 0.66 -0.36 0.46 -0.26
12344 || orf19.5107 || NOT5 || || Protein with similarity to S. cerevisiae Not5p, a member of the transcription regulatory CCR4-NOT complex; required for hyphal growth; antigenic during human oral infection; greater expression in yeast-form cells than hyphae || 1 -0.50 -0.50 -0.68 -0.73 -0.47 -0.58 0.10 0.04 -0.30 0.12 0.15 0.31 0.23 -0.36 0.20 -0.12
12345 || orf19.6641 || || || Ortholog of Candida albicans WO-1 : CAWG_01892 || 1 -0.52 -0.49 -1.35 -0.92 -0.71 -1.01 -0.20 0.33 -0.50 -1.02 0.40 0.25 -0.35 -0.32 -0.30 0.57
12346 || orf19.111 || CAN2 || || Basic amino acid permease; arginine metabolism; regulated by Nrg1/Tup1; caspofungin, flucytosine induced; colony morphology-related regulation by Ssn6; Hap43-repressed; rat catheter and Spider biofilm induced; promoter bound by Efg1 || 1 -0.94 -0.90 -2.09 -2.12 -0.74 -2.43 -0.11 -0.44 -0.67 -1.16 0.41 0.65 -1.41 -0.60 -0.78 1.27
12347 || orf19.4829 || DOA1 || || WD repeat protein; required for ubiquitin-mediated protein degradation; role in control of cellular ubiquitin levels; may promote efficient NHEJ in postdiauxic/stationary phase; Spider biofilm repressed || 1 -0.93 -0.96 -1.14 -1.06 -1.23 -1.12 -0.07 -0.28 -0.78 -0.54 0.30 0.40 -1.21 -0.42 -0.06 0.67
12348 || orf19.3873 || ARC40 || || Protein similar to S. cerevisiae Arc40; involved in actin filament organization in S. cerevisiae; transposon mutation affects filamentous growth; rat catheter and Spider biofilm repressed || 1 -0.66 -0.76 -0.80 -0.78 -0.54 -0.55 0.24 0.07 -0.32 -0.31 0.25 0.31 -0.50 -0.27 0.02 0.31
12349 || orf19.798 || TAF14 || || Putative DNA-binding transcription factor; TFIIF subunit; macrophage-induced protein; possibly required for yeast cell adherence to silicone substrate; mutant has pleiotrophic effects || 1 -0.67 -0.68 -1.04 -0.96 -0.50 -0.43 -0.11 0.14 -0.71 -0.14 0.44 0.12 -0.29 0.06 -0.12 -0.27
12350 || orf19.6566 || || || Ortholog of C. dubliniensis CD36 : Cd36_71420, C. parapsilosis CDC317 : CPAR2_300980, Candida tenuis NRRL Y-1498 : CANTEDRAFT_94952 and Debaryomyces hansenii CBS767 : DEHA2A05346g || 1 -0.34 -0.51 -1.24 -1.35 -0.33 -1.12 0.28 0.22 -0.09 -0.11 -0.28 -0.17 -0.27 -0.40 -0.02 -0.12
12351 || orf19.6698 || || || Ortholog(s) have asparagine-tRNA ligase activity, role in mitochondrial asparaginyl-tRNA aminoacylation and mitochondrion localization || 1 -0.52 -0.43 -1.01 -1.29 -0.51 -1.03 0.37 0.05 0.23 0.09 -0.08 -0.10 -0.58 -0.17 0.18 -0.10
12352 || orf19.7237 || || || Ortholog(s) have arylformamidase activity and role in NAD biosynthetic process || 1 -0.62 -0.80 -0.75 -0.89 -0.48 -0.81 -0.11 0.21 0.19 0.18 -0.39 -0.19 -0.73 -0.34 -0.22 0.05
12353 || orf19.3950 || MSM1 || || Mitochondrial methionyl-tRNA synthetase (MetRS); functionally complements methionine auxotrophy of an E. coli MetRS mutant; transcript regulated by Nrg1; flow model biofilm induced || 1 -0.77 -0.87 -0.56 -0.95 -0.66 -1.08 0.18 0.13 -0.16 0.13 -0.10 0.03 -0.43 -0.59 -0.02 -0.28
12354 || orf19.2138 || ILS1 || || Putative isoleucyl-tRNA synthetase, the target of drugs including the cyclic beta-amino acid icofungipen/PLD-118/BAY-10-8888 and mupirocin; protein present in exponential and stationary growth phase yeast cultures || 1 -1.35 -1.29 -1.14 -1.31 -1.37 -0.94 0.51 0.23 0.62 0.42 0.27 0.59 -0.49 0.72 -1.02 0.42
12355 || orf19.5328 || GCN1 || || Ortholog(s) have role in regulation of translational elongation and cytosolic ribosome, extracellular region, mitochondrion localization || 1 -1.04 -1.10 -1.00 -0.80 -0.77 -0.94 0.11 0.38 0.08 0.41 0.14 0.14 -0.73 0.37 -0.86 0.12
12356 || orf19.2965 || || || Putative guanyl-nucleotide exchange factor; Spider biofilm repressed || 1 -0.46 -0.36 -0.41 -0.54 -0.34 -0.54 0.17 0.34 0.00 0.06 0.12 -0.04 -0.52 0.28 -0.28 -0.08
12357 || orf19.496 || || || Ortholog(s) have DNA-dependent ATPase activity, dinucleotide insertion or deletion binding, guanine/thymine mispair binding activity, role in mismatch repair, mitochondrial DNA repair and mitochondrion localization || 1 -1.39 -1.42 -1.93 -1.34 -0.09 -0.90 0.28 0.23 0.27 0.85 0.39 0.16 -1.01 0.37 -0.75 0.12
12358 || orf19.2286 || || || Putative deoxyhypusine hydroxylase; ketoconazole-induced; protein level decreases in stationary phase cultures; required for biofilm formation; Spider biofilm repressed || 1 -0.96 -1.04 -0.93 -0.86 -0.44 -0.24 -0.29 -0.10 -0.36 -0.30 0.24 -0.20 -0.59 -0.21 -1.06 0.22
12359 || orf19.7082 || || || S-adenosylmethionine transporter of the mitochondrial inner membrane; mitochondrial carrier family; predicted role in biotin biosynthesis and respiratory growth; Spider biofilm repressed || 1 -1.05 -1.15 -1.32 -1.29 -0.37 -0.73 0.20 0.43 -0.07 -0.06 0.14 -0.16 -0.60 0.13 -1.36 0.35
12360 || orf19.7082 || || || S-adenosylmethionine transporter of the mitochondrial inner membrane; mitochondrial carrier family; predicted role in biotin biosynthesis and respiratory growth; Spider biofilm repressed || 1 -1.18 -1.21 -1.29 -1.07 -0.27 -0.63 0.12 0.55 0.08 -0.13 0.22 -0.09 -0.76 0.47 -1.46 0.32
12361 || orf19.486 || NIP100 || || p150 subunit of dynactin; required for normal spindle formation and position || 1 -1.01 -1.05 -0.86 -0.70 -1.11 -1.46 0.16 -0.19 -0.17 -0.39 -0.18 0.07 -0.58 0.80 -1.23 0.48
12362 || orf19.486 || NIP100 || || p150 subunit of dynactin; required for normal spindle formation and position || 1 -1.26 -1.19 -1.25 -1.00 -1.20 -1.73 -0.08 -0.50 -0.31 -0.58 -0.59 -0.11 -0.35 0.50 -1.43 0.42
12363 || orf19.5801 || RNR21 || || Ribonucleoside-diphosphate reductase; regulated by tyrosol and cell density; ciclopirox olamine, fluconazole or flucytosine induced; regulated by Sef1, Sfu1, and Hap43 || 1 -2.00 -1.99 -1.68 -1.47 -1.87 -1.85 -0.14 -0.26 -0.50 -0.75 0.04 -0.18 -0.75 0.48 -2.19 0.21
12364 || orf19.5801 || RNR21 || || Ribonucleoside-diphosphate reductase; regulated by tyrosol and cell density; ciclopirox olamine, fluconazole or flucytosine induced; regulated by Sef1, Sfu1, and Hap43 || 1 -1.76 -1.81 -1.60 -1.07 -1.76 -1.78 -0.09 -0.22 -0.41 -0.87 0.26 -0.31 -0.70 0.67 -1.75 0.38
12365 || orf19.1427 || || || Putative transporter; fungal-specific; Spider biofilm induced || 1 -1.46 -1.26 -0.86 -1.01 -0.60 -1.06 -0.24 -0.09 -0.21 -0.91 -0.14 0.14 -0.39 0.36 -0.92 0.30
12366 || orf19.4002 || DUN1 || || Protein similar to S. cerevisiae Dun1p, which is a serine-threonine protein kinase involved in DNA damage cell-cycle checkpoint; induced under Cdc5p depletion || 1 -1.13 -0.88 -1.13 -0.64 -0.50 -0.93 -0.27 0.12 -0.14 0.08 -0.06 -0.01 -0.35 0.17 -0.92 0.34
12367 || orf19.767 || ERG3 || || C-5 sterol desaturase; introduces C-5(6) double bond into episterol; some clinical isolates show increased azole resistance and defects in hyphal growth and virulence; Efg1p-repressed; fluconazole-induced || 1 -1.73 -1.54 -1.56 -1.38 -1.78 -0.90 0.01 -0.18 0.00 -0.96 -0.46 -0.35 0.39 -0.18 -1.79 0.20
12368 || orf19.6995 || ATO6 || || Putative fungal-specific transmembrane protein || 1 -2.03 -2.07 -1.33 -1.74 -2.61 -0.84 0.32 -0.52 0.56 -1.35 -0.77 0.04 -0.79 -0.20 -1.54 0.33
12369 || orf19.3956 || || || Ortholog(s) have glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity and role in endoplasmic reticulum organization, glutaminyl-tRNAGln biosynthesis via transamidation || 1 -0.54 -0.83 -0.65 -0.93 -0.88 -0.51 0.15 -0.33 -0.00 -0.38 0.04 0.07 -0.58 0.13 -0.57 0.55
12370 || orf19.6937 || PTR22 || || Oligopeptide transporter involved in uptake of di-/tripeptides; regulated by Stp2 and Stp3; transcript induced upon phagocytosis by macrophage; repressed by Rim101 at pH 8; flow model biofilm induced || 1 -2.35 -2.33 -2.39 -2.93 -2.80 -1.56 -0.09 -0.82 -0.87 -1.67 0.81 0.31 -0.88 -0.45 -1.62 0.85
12371 || orf19.6937 || PTR22 || || Oligopeptide transporter involved in uptake of di-/tripeptides; regulated by Stp2 and Stp3; transcript induced upon phagocytosis by macrophage; repressed by Rim101 at pH 8; flow model biofilm induced || 1 -2.27 -2.20 -1.98 -2.75 -2.61 -1.34 0.08 -0.47 -0.51 -1.38 0.96 0.48 -0.60 -0.14 -1.50 1.08
12372 || orf19.6937 || PTR22 || || Oligopeptide transporter involved in uptake of di-/tripeptides; regulated by Stp2 and Stp3; transcript induced upon phagocytosis by macrophage; repressed by Rim101 at pH 8; flow model biofilm induced || 1 -1.59 -1.82 -1.41 -2.10 -2.31 -1.15 0.06 -0.46 -0.35 -1.26 0.92 0.71 -0.51 0.02 -1.22 0.98
12373 || orf19.6937 || PTR22 || || Oligopeptide transporter involved in uptake of di-/tripeptides; regulated by Stp2 and Stp3; transcript induced upon phagocytosis by macrophage; repressed by Rim101 at pH 8; flow model biofilm induced || 1 -1.92 -2.06 -1.41 -2.05 -2.52 -1.43 0.00 -0.33 -0.32 -1.32 1.02 0.69 -0.28 -0.34 -1.57 0.47
12374 || orf19.6937 || PTR22 || || Oligopeptide transporter involved in uptake of di-/tripeptides; regulated by Stp2 and Stp3; transcript induced upon phagocytosis by macrophage; repressed by Rim101 at pH 8; flow model biofilm induced || 1 -1.08 -1.08 -1.12 -1.34 -1.78 -1.33 -0.10 -0.70 -0.39 -1.57 0.60 0.44 -0.35 -0.43 -1.23 0.71
12375 || orf19.7404 || || || Catabolic L-serine (L-threonine) deaminase;, catalyzes degradation of L-serine and L-threonine; required to use serine or threonine as a sole nitrogen source; Spider biofilm repressed || 1 -0.65 -0.72 -1.26 -1.45 -1.07 -0.41 0.22 0.02 -0.09 -1.01 -0.14 -0.36 -0.51 -0.19 -1.48 0.51
12376 || orf19.406 || ERG1 || || Squalene epoxidase, epoxidation of squalene to 2,3(S)-oxidosqualene; ergosterol biosynthesis; allylamine antifungal drug target; NADH reducing cofactor but S. cerevisiae Erg1 uses NADPH; flow model biofilm induced; Spider biofilm repressed || 1 -1.67 -1.67 -2.25 -3.37 -2.29 -2.04 0.40 0.22 0.45 -1.29 0.34 -0.12 -0.66 -0.34 -2.86 0.59
12377 || orf19.406 || ERG1 || || Squalene epoxidase, epoxidation of squalene to 2,3(S)-oxidosqualene; ergosterol biosynthesis; allylamine antifungal drug target; NADH reducing cofactor but S. cerevisiae Erg1 uses NADPH; flow model biofilm induced; Spider biofilm repressed || 1 -0.93 -0.93 -1.34 -2.43 -1.62 -1.42 0.64 0.83 0.68 -1.16 0.99 0.61 -0.12 -0.29 -2.71 0.73
12378 || orf19.922 || ERG11 || || Lanosterol 14-alpha-demethylase; cytochrome P450 family; role in ergosterol biosynthesis; target of azole antifungals; may contribute to drug resistance; azole or flow model biofilm induced; drug treated biofilm induced; hypoxia regulated || 1 -1.19 -1.25 -1.44 -1.69 -1.66 -1.35 0.52 0.60 0.62 0.03 0.65 0.45 -0.62 -0.42 -1.76 0.31
12379 || orf19.386 || SAM4 || || Putative S-adenosylmethionine-homocysteine methyltransferase; Hap43-repressed; alkaline induced; Spider biofilm repressed || 1 -2.16 -2.22 -2.17 -2.09 -1.06 -1.21 0.92 0.29 0.71 -0.69 0.63 0.48 -1.96 -1.39 -2.05 0.66
12380 || orf19.386 || SAM4 || || Putative S-adenosylmethionine-homocysteine methyltransferase; Hap43-repressed; alkaline induced; Spider biofilm repressed || 1 -2.36 -2.63 -2.62 -2.75 -1.39 -1.46 0.97 0.07 0.45 -0.93 0.56 0.48 -1.84 -1.02 -1.98 0.43
12381 || orf19.4233 || THR4 || || Putative threonine synthase; protein present in exponential and stationary growth phase yeast cultures; Gcn4p-regulated; sumoylation target || 1 -0.34 -0.61 -1.03 -0.74 -0.56 -0.68 0.67 0.43 0.16 -0.33 0.64 -0.01 -0.37 -0.12 -0.48 -0.12
12382 || orf19.5505 || HIS7 || || Putative imidazole glycerol phosphate synthase; histidine biosynthesis; no human/murine homolog; transcription induced by histidine starvation; regulated by Gcn2p and Gcn4p; higher protein level in stationary phase || 1 -0.79 -1.15 -1.87 -1.29 -1.45 -1.55 1.00 0.57 0.76 -0.59 0.49 0.17 -0.65 -0.21 -0.98 0.18
12383 || orf19.4811 || || || Putative tricarboxylate carrier family protein; localized to the mitochondrial membrane || 1 -0.58 -0.70 -0.85 -0.74 -0.71 -0.65 0.27 0.01 0.17 -0.14 -0.10 -0.06 -0.66 -0.08 -0.04 0.08
12384 || orf19.394 || || || Putative kynureninase; predicted role in NAD biosynthesis; Hap43-repressed gene; flow model biofilm induced || 1 -1.29 -1.39 -1.38 -1.44 -1.16 -1.16 0.75 0.38 0.41 -0.72 0.41 0.22 -0.88 -0.03 -0.09 0.61
12385 || orf19.780 || DUR1,2 || || Urea amidolyase; hydrolyzes urea to CO2; use of urea as N source and for hyphal switch in macrophage; regulated by Nrg1/Hap43; required for virulence; promotes mouse kidney and brain colonization; rat catheter and flow model biofilm induced || 1 -2.49 -2.43 -2.00 -2.34 -1.82 -1.57 1.93 0.62 0.85 -1.24 -0.17 -0.23 -1.34 0.27 -1.08 0.13
12386 || orf19.780 || DUR1,2 || || Urea amidolyase; hydrolyzes urea to CO2; use of urea as N source and for hyphal switch in macrophage; regulated by Nrg1/Hap43; required for virulence; promotes mouse kidney and brain colonization; rat catheter and flow model biofilm induced || 1 -2.13 -2.18 -2.33 -1.99 -1.62 -1.63 1.36 0.58 1.12 -1.21 -0.09 -0.12 -1.50 0.51 -1.08 0.39
12387 || orf19.780 || DUR1,2 || || Urea amidolyase; hydrolyzes urea to CO2; use of urea as N source and for hyphal switch in macrophage; regulated by Nrg1/Hap43; required for virulence; promotes mouse kidney and brain colonization; rat catheter and flow model biofilm induced || 1 -2.44 -2.00 -2.02 -1.91 -1.95 -1.27 1.47 0.51 1.07 -0.87 0.04 -0.09 -1.47 0.21 -1.11 0.67
12388 || orf19.5639 || HIS4 || || Multifunctional enzyme that catalyzes three steps of histidine biosynthesis, with phosphoribosyl-AMP cyclohydrolase, phosphoribosyl-ATP diphosphatase, and histidinol dehydrogenase activities; required for wild-type adhesion to human calls || 1 -1.51 -1.58 -1.32 -1.04 -1.69 -1.52 0.75 0.33 0.73 -0.61 -0.09 0.11 -0.90 -0.38 -0.94 0.26
12389 || orf19.5484 || SER1 || || Putative 3-phosphoserine aminotransferase; predicted role in serine and glycine biosynthesis; protein present in exponential and stationary yeast growth phases; Spider biofilm repressed || 1 -0.81 -0.67 -0.98 -0.85 -0.78 -0.90 0.48 0.16 0.31 -0.75 -0.07 0.03 -1.01 -0.03 -0.50 -0.09
12390 || orf19.2525 || LYS12 || || Homoisocitrate dehydrogenase; catalyzes 4th step in the alpha-aminoadipate pathway of lysine biosynthesis; clade-associated gene expression; protein level decreases in stationary phase cultures; Spider biofilm repressed || 1 -0.89 -0.91 -1.24 -1.34 -1.05 -0.89 0.71 -0.06 0.52 -0.83 -0.35 -0.07 -0.94 -0.05 -1.18 0.23
12391 || orf19.6994 || BAT22 || || Putative branched chain amino acid aminotransferase; regulated by Gcn4p; induced by farnesol treatment, GlcNAc, amino acid starvation (3-aminotriazole treatment); present in exponential and stationary growth phase yeast cultures || 1 -0.90 -0.98 -1.45 -1.17 -1.16 -1.13 0.60 0.42 0.38 -0.20 -0.00 -0.19 -0.46 0.28 -0.61 -0.23
12392 || orf19.1559 || HOM2 || || Aspartate-semialdehyde dehydrogenase; forms a homodimer; conserved in bacteria, archaea, and fungi but not in mammals; ketoconazole-repressed; protein present in exponential and stationary growth phase yeast cultures; GlcNAc-induced protein || 1 -0.99 -1.12 -1.03 -0.89 -0.81 -1.22 0.99 0.39 0.73 -0.04 0.31 0.39 -0.78 0.20 -0.57 0.34
12393 || orf19.4549 || FGR38 || || Protein lacking an ortholog in S. cerevisiae; member of a family of related proteins; transposon mutation affects filamentous growth; macrophage-induced gene; Hap43p-repressed gene || 1 -0.94 -0.98 -0.61 -0.64 -0.88 -0.51 0.18 0.06 0.19 -0.19 -0.04 0.28 -0.22 0.30 -0.41 0.30
12394 || orf19.2484 || || || Has domain(s) with predicted peptidase activity and role in proteolysis || 1 -0.78 -0.65 -0.64 -0.57 -0.70 -0.60 0.23 -0.04 0.18 -0.37 0.07 0.05 -0.03 0.24 -0.28 0.18
12395 || orf19.4549 || FGR38 || || Protein lacking an ortholog in S. cerevisiae; member of a family of related proteins; transposon mutation affects filamentous growth; macrophage-induced gene; Hap43p-repressed gene || 1 -0.67 -0.58 -0.79 -0.43 -0.50 -0.41 0.09 0.10 0.24 -0.07 -0.26 0.42 -0.37 0.04 -0.33 0.21
12396 || orf19.3065 || DAO1 || || Putative D-amino acid oxidase; transcription is regulated upon yeast-hyphal switch || 1 -0.32 -0.39 -0.62 -0.49 -0.50 -0.62 0.11 0.18 0.14 -0.05 0.03 0.38 -0.39 0.01 -0.16 0.03
12397 || orf19.2129 || || || Ortholog of S. cerevisiae Spo71; a meiosis-specific protein required for spore wall formation during sporulation in S. cerevisiae; possibly an essential gene, disruptants not obtained by UAU1 method || 1 -0.70 -0.65 -0.81 -0.73 -0.23 -0.05 0.29 0.11 0.42 -0.04 -0.14 0.24 -0.58 0.08 -0.15 0.25
12398 || orf19.1457 || || || Putative RNA polymerase transcription factor TFIIH core component; possibly an essential gene, disruptants not obtained by UAU1 method || 1 -0.86 -1.08 -0.93 -0.83 -0.10 0.00 0.08 -0.11 0.25 -0.02 0.05 0.31 -0.59 0.29 0.08 0.41
12399 || orf19.2289 || ARP3 || || Protein with Myo5p-dependent localization to cortical actin patches at hyphal tip; mutation confers hypersensitivity to cytochalasin D; Spider biofilm repressed || 1 -1.21 -1.28 -0.96 -0.98 -0.27 -0.56 -0.08 0.02 0.05 -0.10 0.23 0.35 -0.89 0.41 -0.35 0.35
12400 || orf19.1373 || INP51 || || Putative phosphatidylinositol-4,5-bisphosphate phosphatase; involved in maintenance of phosphoinositide levels; affects hyphal growth, virulence, cell integrity; interacts with Irs4p || 1 -1.11 -1.30 -0.81 -1.04 -0.36 -0.83 -0.25 -0.39 -0.32 -0.30 0.58 0.32 -0.85 -0.17 -0.34 0.68
12401 || orf19.3035 || || || Ortholog(s) have ATP-dependent DNA helicase activity, chromatin DNA binding, methylated histone residue binding, rDNA binding activity || 1 -0.62 -0.91 -0.68 -0.75 -0.06 -0.33 -0.02 0.19 -0.12 -0.19 0.39 0.30 -0.55 -0.08 -0.04 0.17
12402 || orf19.3177 || || || Ortholog(s) have 2,5-diamino-6-ribitylamino-4(3H)-pyrimidinone 5'-phosphate deaminase activity, pseudouridine synthase activity, role in riboflavin biosynthetic process, tRNA pseudouridine synthesis and cytosol localization || 1 -0.88 -1.13 -1.02 -0.87 -0.01 -0.54 0.14 0.20 -0.18 -0.34 0.43 0.31 -0.68 -0.39 -0.12 0.18
12403 || orf19.7265 || || || Putative zinc-finger domain protein with a predicted role in pre-mRNA splicing; Hap43-repressed; Spider biofilm repressed || 1 -0.90 -0.94 -0.81 -0.80 -0.05 -0.18 -0.06 0.08 0.04 -0.47 0.30 0.21 -0.84 -0.27 -0.38 0.38
12404 || orf19.6837 || FMA1 || || Putative oxidoreductase; induced by ciclopirox olamine; upregulation correlates with clinical development of fluconazole resistance; Spider biofilm repressed || 1 -2.13 -2.18 -2.49 -2.80 -0.51 -1.11 -0.26 -0.38 -0.47 -1.01 1.09 0.40 -1.86 -0.32 -1.33 0.95
12405 || orf19.7419 || HNT2 || || Putative dinucleoside triphosphate hydrolase; induced upon low-level peroxide stress || 1 -1.00 -0.93 -1.33 -1.33 -0.25 -0.27 0.17 0.27 -0.05 -0.64 0.81 0.33 -0.87 -0.10 -0.33 0.51
12406 || orf19.6837 || FMA1 || || Putative oxidoreductase; induced by ciclopirox olamine; upregulation correlates with clinical development of fluconazole resistance; Spider biofilm repressed || 1 -0.88 -0.85 -1.37 -1.56 -0.10 -0.64 -0.28 -0.16 -0.10 -0.92 0.92 0.60 -1.23 -0.27 -1.02 0.89
12407 || orf19.2286 || || || Putative deoxyhypusine hydroxylase; ketoconazole-induced; protein level decreases in stationary phase cultures; required for biofilm formation; Spider biofilm repressed || 1 -0.99 -0.99 -1.52 -1.39 -0.29 -0.16 -0.02 -0.10 -0.47 -0.16 0.16 0.08 -0.63 0.32 -1.00 0.54
12408 || orf19.4491 || ERG20 || || Putative farnesyl pyrophosphate synthetase involved in isoprenoid and sterol biosynthesis, based on similarity to S. cerevisiae Erg20p; likely to be essential for growth, based on an insertional mutagenesis strategy || 1 -1.20 -1.20 -1.42 -1.57 -0.62 -0.58 -0.09 0.11 -0.38 0.03 0.46 0.73 -0.46 0.26 -0.77 0.55
12409 || orf19.1095 || GLE2 || || Putative nuclear pore complex; possibly an essential gene, disruptants not obtained by UAU1 method; rat catheter biofilm repressed || 1 -0.86 -0.81 -1.07 -0.85 -0.41 -0.28 -0.16 0.16 -0.27 -0.18 0.49 0.22 -0.43 0.36 -0.28 0.31
12410 || orf19.4478 || || || Ortholog(s) have aspartate-tRNA ligase activity, role in mitochondrial aspartyl-tRNA aminoacylation and mitochondrion localization || 1 -0.81 -0.82 -0.83 -1.23 -0.09 0.03 -0.04 0.02 0.05 -0.25 0.46 0.49 -0.35 -0.18 -0.14 0.59
12411 || orf19.2835 || || || Ortholog(s) have SUMO activating enzyme activity, role in cellular response to DNA damage stimulus, protein sumoylation, regulation of mitotic cell cycle and SUMO activating enzyme complex, cytosol localization || 1 -0.74 -0.82 -1.09 -1.57 -0.26 -0.06 0.10 0.01 -0.08 -0.28 0.44 0.12 -0.04 0.07 -0.29 0.85
12412 || orf19.2334 || BIG1 || || Endoplasmic reticulum (ER) protein; ortholog of S. cerevisiae Big1; required for beta-1,6-glucan synthesis, filamentation, adhesion, and virulence; rat catheter biofilm repressed || 1 -0.98 -1.13 -1.53 -1.48 -0.33 -0.35 0.67 0.49 0.24 -0.40 0.65 0.32 -0.19 -0.23 -0.30 0.89
12413 || orf19.2335 || || || Putative aspartyl aminopeptidase; stationary phase enriched protein; mutation confers hypersensitivity to 5-fluorouracil (5-FU); Hog1-induced; planktonic growth-induced; rat catheter and Spider biofilm repressed || 1 -1.08 -1.22 -1.87 -2.17 -0.93 -1.00 0.70 0.27 0.25 -1.00 0.67 0.14 -0.59 -0.18 -0.94 0.54
12414 || orf19.5480 || ILV1 || || Putative threonine dehydratase; regulated by Gcn4 and Gcn2; induced by amino acid starvation (3-AT); protein present in yeast exponential and stationary phase cultures; early-stage flow model biofilm induced || 1 -1.45 -1.50 -1.52 -1.78 -0.92 -0.51 0.77 0.29 0.36 -0.70 0.41 0.33 -0.44 -0.19 -0.61 0.60
12415 || orf19.5480 || ILV1 || || Putative threonine dehydratase; regulated by Gcn4 and Gcn2; induced by amino acid starvation (3-AT); protein present in yeast exponential and stationary phase cultures; early-stage flow model biofilm induced || 1 -1.61 -1.59 -2.06 -2.03 -0.89 -0.63 0.72 0.29 0.63 -0.64 0.32 0.43 -0.61 0.09 -0.65 0.46
12416 || orf19.2988 || || || Predicted aminotransferase based on S. pombe ortholog SPBC660.12c; flow model biofilm induced || 1 -1.18 -1.02 -1.36 -1.56 -0.79 -0.48 0.40 -0.05 0.41 -1.09 0.15 0.22 -0.66 0.15 -0.70 0.40
12417 || orf19.1799 || GAP5 || || Putative general amino acid permease; fungal-specific (no human or murine homolog) || 1 -1.22 -1.21 -1.42 -2.20 -0.35 -0.23 0.59 0.26 0.55 -0.60 0.20 0.19 -0.69 0.27 -0.93 0.64
12418 || orf19.5104 || LTP1 || || Putative protein phosphatase of the PTP family (tyrosine-specific), similar to S. cerevisiae Ltp1p || 1 -0.63 -0.68 -0.70 -0.85 -0.15 -0.12 0.10 0.17 -0.20 -0.19 0.19 0.03 -0.26 0.12 -0.32 -0.14
12419 || orf19.4304 || GAP1 || || Amino acid permease; antigenic in human/mouse; 10-12 transmembrane regions; regulated by nitrogen source; alkaline, GlcNAc, phagocytosis induced; WT virulence in mice; Spider and flow model biofilm induced || 1 -3.37 -3.09 -4.98 -5.38 -1.25 -1.72 0.43 0.12 -0.27 -0.90 0.21 -0.09 -1.99 0.67 -1.15 0.50
12420 || orf19.1799 || GAP5 || || Putative general amino acid permease; fungal-specific (no human or murine homolog) || 1 -2.44 -2.30 -2.82 -3.65 -0.83 -0.62 0.35 -0.06 0.12 -0.90 -0.00 -0.21 -1.49 0.14 -1.45 0.48
12421 || orf19.2334 || BIG1 || || Endoplasmic reticulum (ER) protein; ortholog of S. cerevisiae Big1; required for beta-1,6-glucan synthesis, filamentation, adhesion, and virulence; rat catheter biofilm repressed || 1 -1.32 -1.33 -1.44 -1.77 -0.71 -0.61 0.20 -0.04 -0.09 -0.83 0.30 0.00 -0.57 -0.20 -0.93 0.27
12422 || orf19.4581 || || || Putative glycosylphosphatidylinositol-alpha 1,4 mannosyltransferase I; regulated by Tsa1p, Tsa1Bp under H2O2 stress conditions || 1 -3.02 -3.24 -3.17 -3.21 -1.90 -1.71 0.21 -0.62 -0.44 -1.71 0.15 -0.23 -0.79 -0.54 -1.46 0.61
12423 || orf19.4581 || || || Putative glycosylphosphatidylinositol-alpha 1,4 mannosyltransferase I; regulated by Tsa1p, Tsa1Bp under H2O2 stress conditions || 1 -2.36 -2.08 -2.61 -2.33 -1.12 -1.36 0.32 -0.48 -0.30 -1.40 0.44 -0.00 -0.21 -0.45 -1.07 0.90
12424 || orf19.3825 || RCE1 || || Putative Type II CAAX prenyl protease; induced during the mating process || 1 -1.33 -1.55 -1.55 -1.37 -0.79 -0.96 0.14 0.01 -0.09 -0.57 -0.32 -0.30 -0.40 -0.18 -0.49 0.18
12425 || orf19.6304 || LYS5 || || Phosphopantetheinyl transferase; enzyme of lysine biosynthesis; modifies, and thereby activates, Lys2p alpha-aminoadipate reductase; functional homolog of S. cerevisiae Lys5p || 1 -1.38 -1.37 -1.75 -1.76 -0.75 -0.96 -0.17 -0.25 -0.46 -0.92 0.12 -0.12 -0.30 0.40 -0.37 0.65
12426 || orf19.5358 || || || Phosphorylated protein of unknown function || 1 -1.02 -1.00 -1.12 -1.23 -0.20 -0.60 -0.05 -0.18 -0.30 -0.62 0.12 -0.31 -0.41 -0.02 -0.14 0.07
12427 || orf19.5197 || APE2 || || Neutral arginine, alanine, leucine specific metallo-aminopeptidase; purified from cell wall/intracellular fractions; protein repressed during mating; Hog1, farnesol-induced; may be essential (UAU1 method); rat catheter biofilm repressed || 1 -0.67 -0.68 -1.13 -1.11 -0.38 -0.68 0.22 0.04 -0.11 -0.38 0.12 0.11 -0.22 0.12 -0.26 -0.24
12428 || orf19.2455 || || || Ortholog(s) have gamma-glutamyltransferase activity, omega peptidase activity, role in glutathione catabolic process and cytoplasm, nucleus localization || 1 -1.33 -1.42 -2.08 -1.70 -0.37 -0.26 0.04 -0.10 0.09 -0.28 0.16 0.32 -0.30 0.17 0.49 0.60
12429 || orf19.1070 || || || Ortholog(s) have cytoplasm localization || 1 -1.70 -1.44 -2.15 -2.44 -0.50 -0.28 -0.42 -0.31 -0.26 -1.01 0.33 0.58 -0.33 0.14 0.03 0.82
12430 || orf19.5965 || || || Ortholog(s) have ubiquitin-ubiquitin ligase activity, role in ER-associated ubiquitin-dependent protein catabolic process, protein ubiquitination, response to stress and cytoplasm, nucleus localization || 1 -0.91 -0.93 -1.33 -1.16 -0.44 -0.48 -0.01 -0.23 -0.19 -0.45 0.25 0.25 -0.48 0.07 0.15 0.62
12431 || orf19.6071 || || || Ortholog(s) have peptide alpha-N-acetyltransferase activity, role in N-terminal peptidyl-methionine acetylation, cytoskeleton organization, mitochondrion inheritance and NatB complex localization || 1 -0.68 -0.87 -1.49 -1.42 -0.56 -0.56 -0.08 -0.09 -0.35 -0.32 0.35 0.27 -0.33 0.16 -0.10 0.35
12432 || orf19.5197 || APE2 || || Neutral arginine, alanine, leucine specific metallo-aminopeptidase; purified from cell wall/intracellular fractions; protein repressed during mating; Hog1, farnesol-induced; may be essential (UAU1 method); rat catheter biofilm repressed || 1 -0.66 -0.63 -0.92 -1.02 -0.36 -0.43 0.27 0.01 0.07 -0.31 0.21 0.26 -0.16 0.34 -0.01 0.28
12433 || orf19.6304 || LYS5 || || Phosphopantetheinyl transferase; enzyme of lysine biosynthesis; modifies, and thereby activates, Lys2p alpha-aminoadipate reductase; functional homolog of S. cerevisiae Lys5p || 1 -1.08 -0.80 -1.29 -1.48 -0.60 -0.74 0.21 0.22 0.13 -0.53 0.22 -0.05 -0.18 0.39 -0.03 0.80
12434 || orf19.4982 || || || Has domain(s) with predicted role in lipid metabolic process || 1 -1.10 -1.21 -1.34 -1.95 -0.86 -0.87 0.26 0.04 -0.13 -0.87 0.57 0.28 0.17 0.27 -0.20 0.75
12435 || orf19.2484 || || || Has domain(s) with predicted peptidase activity and role in proteolysis || 1 -0.75 -0.65 -0.98 -1.06 -0.74 -0.56 0.52 0.19 -0.13 -0.55 0.35 0.20 -0.04 0.16 0.10 0.71
12436 || orf19.797 || BAT21 || || Putative branched chain amino acid aminotransferase; regulated by Gcn4, Gcn2; induced in response to amino acid starvation (3-aminotriazole treatment); early-stage flow model biofilm formation || 1 -2.25 -2.26 -2.57 -2.52 -1.94 -1.33 0.71 -0.32 0.40 -1.35 0.73 0.79 -0.47 -0.03 0.56 1.11
12437 || orf19.6232 || NPR1 || || Predicted serine/threonine protein kinase, involved in regulation of ammonium transport; induced in core stress response; Hap43p-repressed gene || 1 -1.71 -1.70 -1.63 -1.44 -1.01 -0.59 -0.05 -0.23 -0.25 -1.16 0.53 0.37 0.04 -0.20 0.27 0.98
12438 || orf19.1592 || || || Protein of unknown function; Spider biofilm induced || 1 -1.47 -1.50 -1.46 -1.59 -0.86 -0.53 0.44 -0.28 0.29 -0.32 -0.11 0.22 0.12 -0.28 -0.39 0.18
12439 || orf19.5643 || ECM7 || || Protein involved in control of calcium homeostasis and oxidative stress response; mutants show defects in hyphal growth || 1 -0.89 -0.97 -0.71 -0.87 -0.69 -0.02 -0.11 -0.12 0.04 -0.42 0.03 0.18 -0.44 -0.11 -0.07 0.53
12440 || orf19.3720 || || || Ortholog(s) have endo-1,4-beta-xylanase activity and SCF ubiquitin ligase complex, cytoplasm localization || 1 -1.90 -1.96 -1.70 -2.10 -0.87 0.00 0.08 -0.69 0.03 -1.24 -0.06 0.64 -0.96 -0.05 -0.45 0.57
12441 || orf19.5980 || || || Protein of unknown function; Hap43-repressed gene || 1 -0.78 -1.00 -0.71 -1.08 -0.22 -0.06 -0.18 -0.54 0.23 -0.62 0.19 0.42 -0.17 0.04 -0.03 0.42
12442 || orf19.4889 || || || Predicted MFS family membrane transporter, member of the drug:proton antiporter (12 spanner) (DHA1) family; Spider biofilm induced || 1 -1.38 -1.68 -0.99 -0.82 -1.23 -0.71 -0.32 -0.86 0.22 -0.97 0.27 0.93 -0.57 -0.02 0.37 -0.24
12443 || orf19.4889 || || || Predicted MFS family membrane transporter, member of the drug:proton antiporter (12 spanner) (DHA1) family; Spider biofilm induced || 1 -1.85 -2.12 -1.42 -1.75 -1.94 -0.85 -0.57 -1.06 -0.01 -0.68 0.16 0.60 -0.86 -0.13 0.16 0.13
12444 || orf19.6316 || || || Predicted membrane transporter, member of the L-amino acid transporter-3 (LAT3) family, major facilitator superfamily (MFS) || 1 -1.97 -2.29 -1.12 -0.91 -1.42 -1.09 -0.69 -0.59 -0.35 -0.61 0.26 0.64 -0.77 -0.55 0.37 0.43
12445 || orf19.5165 || || || Ortholog(s) have cytoplasm localization || 1 -1.16 -1.18 -0.57 -0.92 -0.90 -0.87 -0.21 -0.16 -0.35 -0.20 -0.05 0.06 -0.52 -0.34 0.14 0.05
12446 || orf19.2168.3 || || || Ortholog(s) have role in cellular protein localization, cytokinesis, site selection, endoplasmic reticulum inheritance, endoplasmic reticulum tubular network organization, nuclear pore complex assembly, vesicle-mediated transport || 1 -1.72 -1.87 -1.52 -0.94 -1.49 -1.02 -0.59 0.06 -0.35 -0.22 0.32 0.45 -1.04 -0.10 0.08 -0.37
12447 || orf19.5917.3 || || || RNA binding protein required for export of poly(A)+ mRNA from the nucleus; Spider biofilm repressed || 1 -1.66 -1.81 -1.47 -1.21 -1.09 -1.08 -0.29 0.17 -0.38 -0.31 0.70 0.53 -0.44 -0.41 -0.17 0.18
12448 || orf19.5917.3 || || || RNA binding protein required for export of poly(A)+ mRNA from the nucleus; Spider biofilm repressed || 1 -1.64 -1.69 -1.41 -0.95 -1.12 -1.12 -0.46 0.07 -0.46 -0.19 0.79 0.56 -0.69 -0.43 -0.27 0.62
12449 || orf19.5917.3 || || || RNA binding protein required for export of poly(A)+ mRNA from the nucleus; Spider biofilm repressed || 1 -1.15 -1.24 -1.13 -0.79 -1.05 -1.26 -0.54 -0.08 -0.48 -0.44 0.35 0.41 -0.59 -0.52 -0.27 0.12
12450 || orf19.5917.3 || || || RNA binding protein required for export of poly(A)+ mRNA from the nucleus; Spider biofilm repressed || 1 -0.98 -0.99 -1.14 -0.74 -1.03 -1.05 -0.43 -0.07 -0.27 -0.17 0.59 0.68 -0.30 -0.34 -0.06 0.59
12451 || orf19.1977 || URA4 || || Dihydroorotase; protein present in exponential and stationary growth phase yeast cultures || 1 -1.18 -1.34 -1.36 -1.23 -0.92 -0.54 -0.19 -0.01 -0.27 0.38 0.57 0.54 -1.05 -0.20 0.40 0.44
12452 || orf19.4846 || || || GlcNAc-induced protein || 1 -1.59 -2.16 -2.14 -1.67 -0.88 -0.24 -0.55 -0.02 -0.14 -0.07 0.59 0.54 -1.00 -0.51 -0.07 0.44
12453 || orf19.6558 || || || Has domain(s) with predicted zinc ion binding activity, role in ER to Golgi vesicle-mediated transport, intracellular protein transport and COPII vesicle coat localization || 1 -0.65 -0.93 -0.87 -0.70 -0.54 -0.42 -0.42 -0.17 -0.22 0.29 0.17 0.10 -0.19 -0.15 -0.05 0.14
12454 || orf19.6558 || || || Has domain(s) with predicted zinc ion binding activity, role in ER to Golgi vesicle-mediated transport, intracellular protein transport and COPII vesicle coat localization || 1 -0.58 -0.92 -0.74 -1.04 -0.55 -0.46 -0.38 -0.26 -0.29 0.28 0.26 0.25 -0.44 -0.12 0.07 0.33
12455 || orf19.3565 || || || Ortholog of C. dubliniensis CD36 : Cd36_19830, C. parapsilosis CDC317 : CPAR2_206470, Candida tenuis NRRL Y-1498 : CANTEDRAFT_113899 and Debaryomyces hansenii CBS767 : DEHA2C05676g || 1 -0.49 -0.69 -0.72 -0.57 -0.51 -0.15 -0.45 -0.42 -0.36 0.14 0.18 0.04 -0.39 -0.05 0.13 0.27
12456 || orf19.1865 || MCS7 || || S. cerevisiae ortholog Mcs7 has a role in reciprocal meiotic recombination; Spider biofilm repressed || 1 -0.76 -0.99 -0.83 -0.86 -0.19 -0.21 -0.54 -0.17 -0.51 0.14 0.36 0.27 -0.64 0.04 -0.02 0.25
12457 || orf19.2521 || || || Ortholog of C. dubliniensis CD36 : Cd36_26390, Debaryomyces hansenii CBS767 : DEHA2C05302g, Pichia stipitis Pignal : PICST_68531 and Spathaspora passalidarum NRRL Y-27907 : SPAPADRAFT_59916 || 1 -0.79 -0.60 -0.85 -1.15 -0.17 -0.39 -0.32 -0.31 -0.49 -0.27 -0.30 -0.42 -0.50 -0.44 -0.25 -0.06
12458 || orf19.5381 || || || Ortholog(s) have mRNA binding activity || 1 -1.12 -1.39 -1.77 -1.67 -0.65 -0.80 -0.55 -0.60 -1.11 -0.15 -0.53 -0.47 -0.33 -0.43 -0.38 -0.03
12459 || orf19.6365 || PTP1 || || Phosphotyrosine-specific protein phosphatase; rat catheter biofilm induced || 1 -1.54 -1.55 -1.48 -1.74 -0.34 -0.40 -0.70 -0.57 -0.69 -0.08 -0.09 -0.43 -0.78 -0.39 -0.18 0.06
12460 || orf19.6365 || PTP1 || || Phosphotyrosine-specific protein phosphatase; rat catheter biofilm induced || 1 -1.37 -1.47 -1.62 -1.57 -0.43 -0.37 -0.75 -0.53 -0.78 -0.08 -0.14 -0.48 -0.81 -0.36 -0.37 -0.18
12461 || orf19.2711 || || || Similar to S. cerevisiae Elp2, an Elongator complex subunit required for modification of wobble nucleosides in tRNA; repressed in core stress response || 1 -1.25 -1.35 -1.48 -1.49 -0.18 -0.25 -0.80 -0.68 -0.88 0.25 -0.34 -0.36 -0.98 -0.20 -0.67 -0.54
12462 || orf19.7237 || || || Ortholog(s) have arylformamidase activity and role in NAD biosynthetic process || 1 -1.57 -1.54 -1.43 -1.48 -0.62 -0.50 -0.68 -0.43 -0.65 -0.10 -0.68 -0.29 -1.24 0.28 -0.38 0.21
12463 || orf19.6904 || GCN3 || || Putative translation initiator; downregulated in the presence of human whole blood or polymorphonuclear (PMN) cells || 1 -0.88 -0.73 -0.77 -0.84 -0.32 -0.21 -0.44 -0.10 -0.35 -0.00 0.08 -0.08 -0.40 0.24 -0.21 -0.06
12464 || orf19.7362 || SKN1 || || Protein with a role in beta-1,6-glucan synthesis; probable N-glycosylated type II membrane protein; transcript and mRNA length change induced by yeast-hypha transition; induced by Rim101, caspofungin; rat catheter and Spider biofilm induced || 1 -2.01 -1.61 -1.89 -1.78 -0.29 -0.51 -0.52 -1.00 -0.94 -0.62 -0.39 -0.22 -0.37 0.31 -0.62 -0.08
12465 || orf19.5071 || NRP1 || || Ortholog(s) have cytoplasmic stress granule, nucleolus localization || 1 -1.69 -1.42 -1.77 -1.17 -0.92 -1.29 -0.96 -0.69 -1.09 -0.22 -0.01 -0.11 -0.47 -0.38 -0.27 -0.11
12466 || orf19.5071 || NRP1 || || Ortholog(s) have cytoplasmic stress granule, nucleolus localization || 1 -1.89 -1.97 -2.06 -1.25 -0.93 -1.24 -0.90 -0.62 -1.05 -0.17 -0.00 0.10 -0.21 -0.49 -0.30 0.04
12467 || orf19.1991 || || || Ortholog(s) have cytoplasm localization || 1 -0.75 -0.75 -0.99 -0.69 -0.09 -0.52 -0.29 -0.24 -0.46 -0.19 0.03 0.06 -0.29 -0.53 0.13 0.07
12468 || orf19.2597 || MRS2 || || Putative magnesium ion transporter, mitochondrial; fungal-specific (no human or murine homolog) || 1 -1.05 -1.10 -0.90 -0.77 0.01 -0.33 -0.43 -0.31 -0.26 -0.09 -0.09 0.42 -0.40 -0.41 0.23 -0.21
12469 || orf19.6860 || || || Ortholog(s) have CDP-diacylglycerol-inositol 3-phosphatidyltransferase activity, role in phosphatidylinositol biosynthetic process and Golgi apparatus, integral to membrane, mitochondrial outer membrane localization || 1 -1.15 -1.31 -1.43 -1.30 -0.63 -0.49 -0.60 -0.51 -0.50 0.09 -0.29 0.14 -0.48 -0.44 0.34 -0.36
12470 || orf19.6185 || || || Putative pseudouridine-5'-phosphate glycosidase; overlaps orf19.6186 and orf19.6187; Spider biofilm repressed || 1 -0.78 -0.88 -0.49 -0.58 -0.33 -0.00 -0.17 -0.19 -0.16 -0.09 0.11 0.07 -0.74 -0.05 -0.15 0.04
12471 || orf19.2337 || ALP1 || || Cystine transporter; present in pathogenic yeasts (no human or murine homolog); Spider biofilm induced || 1 -1.92 -2.10 -1.33 -1.56 -1.60 -0.53 -0.11 -0.08 -0.74 -0.20 0.11 0.16 -1.85 -0.14 -0.40 -0.35
12472 || orf19.505 || SRV2 || || Adenylate cyclase-associated protein; regulates adenylate cyclase activity; required for wild-type germ tube formation and for virulence in mice; mutant defects in filamentous growth are rescued by cAMP or dbcAMP; Spider biofilm repressed || 1 -0.60 -0.63 -0.56 -0.69 -0.45 -0.41 -0.06 -0.07 -0.11 -0.19 0.11 0.26 -0.70 -0.03 -0.30 -0.26
12473 || orf19.2288 || CCT5 || || T-complex protein 1, epsilon subunit; protein present in exponential and stationary growth phase yeast cultures; Spider biofilm repressed || 1 -0.95 -0.92 -0.88 -0.57 -0.40 -0.71 -0.29 0.08 -0.28 0.14 -0.02 -0.40 -0.85 -0.33 -0.87 -0.19
12474 || orf19.3182 || GIS2 || || Translational activator for mRNAs with internal ribosome entry sites; induced in high iron; repressed by yeast-hypha switch; null exhibits sensitivity to sorbitol, 5-fluorocytosine, and cold temperatures; Spider biofilm repressed || 1 -2.57 -2.68 -2.60 -1.77 -1.79 -2.14 -0.10 0.23 -0.76 -0.07 0.16 -0.30 -2.88 -0.94 -1.70 -0.05
12475 || orf19.3182 || GIS2 || || Translational activator for mRNAs with internal ribosome entry sites; induced in high iron; repressed by yeast-hypha switch; null exhibits sensitivity to sorbitol, 5-fluorocytosine, and cold temperatures; Spider biofilm repressed || 1 -1.87 -2.05 -1.79 -1.17 -1.05 -1.69 -0.13 0.13 -0.95 -0.13 0.56 0.03 -2.23 -1.04 -1.19 -0.22
12476 || orf19.3195 || HIP1 || || Similar to amino acid permeases; alkaline, flucytosine induced; regulated by Plc1, Gcn2 and Gcn4; fungal-specific; Spider biofilm induced || 1 -3.46 -3.24 -2.32 -2.29 -2.59 -2.01 0.14 -0.06 -0.73 -0.06 0.92 -0.12 -2.92 -0.35 -1.09 0.70
12477 || orf19.3195 || HIP1 || || Similar to amino acid permeases; alkaline, flucytosine induced; regulated by Plc1, Gcn2 and Gcn4; fungal-specific; Spider biofilm induced || 1 -1.71 -1.41 -0.89 -1.09 -1.55 -1.29 -0.04 0.27 -0.09 0.35 0.98 0.22 -1.47 -0.17 -0.62 0.66
12478 || orf19.3941 || URA7 || || CTP synthase 1; flucytosine induced; protein present in exponential and stationary growth phase yeast cultures || 1 -1.03 -1.14 -1.11 -1.13 -0.88 -0.57 -0.50 0.00 -0.43 0.60 0.21 0.03 -1.30 -0.10 -0.94 0.06
12479 || orf19.3934 || CAR1 || || Arginase; arginine catabolism; transcript regulated by Nrg1, Mig1, Tup1; colony morphology-related regulation by Ssn6; alkaline induced; protein decreased in stationary phase; sumoylation target; flow model biofilm induced || 1 -0.81 -0.80 -2.61 -2.29 -1.16 -2.26 0.16 0.80 0.04 0.19 0.40 0.40 -1.71 0.20 -1.07 0.09
12480 || orf19.3934 || CAR1 || || Arginase; arginine catabolism; transcript regulated by Nrg1, Mig1, Tup1; colony morphology-related regulation by Ssn6; alkaline induced; protein decreased in stationary phase; sumoylation target; flow model biofilm induced || 1 -0.87 -0.94 -2.27 -2.02 -1.41 -2.37 -0.03 0.56 -0.37 0.09 0.19 -0.01 -1.90 -0.92 -1.14 0.15
12481 || orf19.2953 || TOM20 || || Putative mitochondrial primary import receptor || 1 -1.29 -1.34 -1.67 -1.23 -1.02 -1.55 -0.05 0.51 -0.19 0.17 0.46 0.08 -1.42 -0.25 -0.85 0.04
12482 || orf19.2953 || TOM20 || || Putative mitochondrial primary import receptor || 1 -1.09 -1.21 -1.78 -1.25 -1.15 -1.39 0.26 0.75 0.28 0.38 0.80 0.32 -1.19 -0.22 -0.77 -0.28
12483 || orf19.1626 || || || Deoxyhypusine synthase; catalyzes formation of deoxyhypusine, the first step in hypusine biosynthesis; Spider biofilm repressed || 1 -0.73 -0.79 -1.05 -0.81 -0.91 -1.10 0.04 0.64 -0.24 0.53 0.48 -0.37 -0.56 0.04 -0.78 -0.17
12484 || orf19.169 || CHO2 || || Putative phosphatidyl-ethanolamine N-methyltransferase; fungal-specific (no human or murine homolog); amphotericin B repressed; Hap43p-induced gene || 1 -2.42 -2.39 -3.82 -2.93 -1.82 -3.43 0.68 1.47 -0.89 1.00 -0.14 -1.38 -1.18 0.50 -2.00 -0.94
12485 || orf19.4051 || HTS1 || || Putative tRNA-His synthetase; downregulated upon phagocytosis by murine macrophage; stationary phase enriched protein; Spider biofilm repressed || 1 -0.82 -0.79 -1.31 -0.89 -0.83 -1.04 0.17 0.40 -0.43 0.15 0.21 -0.36 -1.03 -0.42 -0.68 -0.25
12486 || orf19.1402 || CCT2 || || Chaperonin of the cytosolic TCP1 ring complex; protein present in exponential and stationary-phase yeast cells, but higher amounts in stationary phase; GlcNAc-induced protein || 1 -0.56 -0.58 -1.16 -0.97 -0.19 -0.75 -0.09 0.44 -0.66 0.33 0.32 -0.54 -0.71 -0.10 -0.49 -0.03
12487 || orf19.3037 || || || Putative poly(A)-binding protein; regulated by Gcn4p; induced in response to amino acid starvation (3-AT treatment); protein present in exponential and stationary growth phase yeast cultures || 1 -0.57 -0.50 -1.12 -0.75 -0.28 -0.86 -0.12 0.20 -0.62 0.47 0.13 -0.39 -0.62 -0.15 -0.64 -0.36
12488 || orf19.3037 || || || Putative poly(A)-binding protein; regulated by Gcn4p; induced in response to amino acid starvation (3-AT treatment); protein present in exponential and stationary growth phase yeast cultures || 1 -0.50 -0.61 -1.08 -0.56 -0.45 -0.79 -0.00 0.37 -0.33 0.50 0.37 -0.27 -0.74 -0.11 -0.47 -0.15
12489 || orf19.2489 || || || Putative karyopherin beta; repressed by nitric oxide || 1 -0.74 -0.74 -1.23 -1.19 -0.48 -0.88 0.17 0.33 -0.36 0.70 0.17 -0.29 -1.00 -0.19 -0.86 0.08
12490 || orf19.2489 || || || Putative karyopherin beta; repressed by nitric oxide || 1 -1.17 -1.25 -1.90 -1.86 -0.84 -1.11 0.16 0.14 -0.38 0.68 -0.05 -0.71 -1.25 -0.30 -1.24 0.12
12491 || orf19.4051 || HTS1 || || Putative tRNA-His synthetase; downregulated upon phagocytosis by murine macrophage; stationary phase enriched protein; Spider biofilm repressed || 1 -0.79 -0.72 -1.20 -1.28 -0.56 -0.92 0.16 0.32 -0.29 0.22 0.19 -0.33 -0.53 -0.10 -0.41 0.08
12492 || orf19.1378 || SUP35 || || Translation factor eRF3; shows prion-like aggregation in some, not all, studies; partially complements S. cerevisiae sup35 mutant translation defect; species barrier with S. cerevisiae Sup35p prion; gene not regulated by yeast-hyphal switch || 1 -0.95 -0.85 -1.28 -1.36 -0.33 -0.71 0.19 0.41 -0.44 0.22 0.64 -0.23 -0.52 -0.06 -0.65 0.15
12493 || orf19.401 || TCP1 || || Chaperonin-containing T-complex subunit, induced by alpha pheromone in SpiderM medium; stationary phase enriched protein || 1 -1.26 -1.26 -1.58 -1.12 -0.34 -1.11 -0.26 0.45 -0.59 0.40 0.38 -0.25 -0.88 0.24 -0.64 0.09
12494 || orf19.2288 || CCT5 || || T-complex protein 1, epsilon subunit; protein present in exponential and stationary growth phase yeast cultures; Spider biofilm repressed || 1 -0.86 -0.90 -0.96 -0.72 -0.27 -0.57 -0.18 0.29 -0.37 0.43 0.07 0.02 -0.83 0.12 -0.59 -0.09
12495 || orf19.6081 || PHR2 || || Glycosidase; role in vaginal not systemic infection (low pH not neutral); low pH, high iron, fluconazole, Hap43-induced; Rim101-repressed at pH8; rat catheter biofilm induced; Bcr1-repressed in RPMI a/a biofilms || 1 -1.36 -1.65 -1.65 -0.76 -0.89 -0.79 0.01 -0.18 -0.31 0.04 -0.22 -0.44 -0.74 -0.38 0.07 -0.09
12496 || orf19.6081 || PHR2 || || Glycosidase; role in vaginal not systemic infection (low pH not neutral); low pH, high iron, fluconazole, Hap43-induced; Rim101-repressed at pH8; rat catheter biofilm induced; Bcr1-repressed in RPMI a/a biofilms || 1 -0.69 -0.96 -0.97 -0.58 -0.43 -0.51 0.06 -0.09 -0.08 0.02 -0.06 -0.29 -0.27 -0.29 -0.10 0.07
12497 || orf19.579 || FOL1 || || Putative dihydroneopterin aldolase (dihydro-6-hydroxymethylpterin pyrophosphokinase); fungal-specific (no human or murine homolog) || 1 -0.88 -0.89 -1.47 -0.77 -0.73 -0.85 0.32 0.05 0.08 0.17 0.00 0.25 -0.52 -0.16 -0.23 0.03
12498 || orf19.496 || || || Ortholog(s) have DNA-dependent ATPase activity, dinucleotide insertion or deletion binding, guanine/thymine mispair binding activity, role in mismatch repair, mitochondrial DNA repair and mitochondrion localization || 1 -1.10 -1.16 -1.77 -1.24 -0.23 -1.11 0.09 0.02 -0.10 0.33 0.27 0.16 -0.64 -0.16 -0.68 -0.50
12499 || orf19.3035 || || || Ortholog(s) have ATP-dependent DNA helicase activity, chromatin DNA binding, methylated histone residue binding, rDNA binding activity || 1 -1.26 -1.24 -1.69 -1.72 -0.25 -0.72 -0.22 0.07 -0.54 -0.40 0.04 -0.20 -0.78 -0.40 -0.02 -0.35
12500 || orf19.6934 || || || Ortholog(s) have role in protein insertion into mitochondrial membrane from inner side and integral to mitochondrial inner membrane localization || 1 -1.50 -1.34 -1.72 -1.57 -0.31 -0.94 -0.02 0.02 -0.20 -0.24 -0.43 -0.32 -0.70 -0.45 -0.05 -0.35
12501 || orf19.477 || || || Ortholog(s) have role in mitochondrial translation and mitochondrion localization || 1 -1.47 -1.53 -1.71 -1.52 -0.63 -0.80 0.50 0.06 -0.19 0.26 0.39 -0.32 -0.10 -0.81 0.33 -0.64
12502 || orf19.477 || || || Ortholog(s) have role in mitochondrial translation and mitochondrion localization || 1 -1.67 -1.54 -1.80 -1.86 -0.87 -0.91 0.13 0.04 -0.36 0.55 0.30 0.30 -0.60 -1.21 0.24 -0.10
12503 || orf19.1959 || || || Ortholog(s) have ubiquitin-specific protease activity, role in protein deubiquitination and cytosol, ribosome localization || 1 -1.12 -0.94 -1.40 -1.14 -0.50 -1.05 -0.55 0.07 -0.22 0.47 0.14 0.04 -0.30 -0.26 0.24 -0.49
12504 || orf19.4426 || PEX3 || || Putative peroxisomal protein involved in targeting proteins into peroxisomes; possibly an essential gene, disruptants not obtained by UAU1 method || 1 -1.34 -1.14 -1.11 -1.20 -0.75 -0.83 -0.25 0.01 -0.29 0.38 0.08 0.17 -0.33 -0.34 0.34 -0.50
12505 || orf19.2214 || || || Ortholog(s) have structural constituent of ribosome activity and mitochondrial large ribosomal subunit localization || 1 -1.94 -1.87 -2.31 -1.54 -0.81 -1.04 0.08 0.33 0.01 0.76 0.30 0.09 -0.16 -0.66 0.01 -0.55
12506 || orf19.805 || || || Putative protein of unknown function; possibly mitochondrial; Hap43-repressed; Spider biofilm repressed || 1 -0.78 -0.68 -0.89 -0.66 -0.15 -0.60 -0.09 0.11 -0.03 0.40 0.09 0.23 -0.24 -0.13 -0.01 -0.27
12507 || orf19.7386 || || || Ortholog(s) have ribosome binding activity || 1 -1.40 -1.39 -1.35 -1.16 -0.62 -1.27 0.17 0.46 0.17 0.84 0.26 0.01 -0.46 -0.31 -0.12 -0.43
12508 || orf19.4022 || SDH4 || || Succinate dehydrogenase, membrane subunit; induced in high iron || 1 -1.49 -1.62 -1.55 -1.34 -0.71 -0.56 -0.41 0.19 -0.22 0.63 0.19 0.02 -1.02 -0.57 -0.38 -0.35
12509 || orf19.1085 || || || Ortholog(s) have ubiquitin-protein ligase activity || 1 -1.07 -1.10 -0.98 -0.80 -0.47 -0.40 -0.25 0.04 -0.34 -0.13 0.21 0.33 -0.35 -0.06 0.04 0.04
12510 || orf19.6665 || || || Ortholog(s) have Ran GTPase binding, nucleocytoplasmic transporter activity || 1 -1.66 -1.40 -1.50 -1.42 -0.66 -0.57 -0.42 -0.26 -0.54 -0.04 0.36 0.06 -0.34 -0.49 -0.23 -0.01
12511 || orf19.1956 || || || Ortholog(s) have role in reciprocal meiotic recombination and mitochondrion localization || 1 -1.68 -1.60 -2.52 -2.29 -0.91 -1.19 -0.06 0.27 -0.32 0.32 -0.27 -0.15 -0.68 -0.49 -0.37 -0.61
12512 || orf19.2214 || || || Ortholog(s) have structural constituent of ribosome activity and mitochondrial large ribosomal subunit localization || 1 -2.19 -1.87 -2.94 -2.42 -0.86 -1.16 -0.12 0.23 -0.35 0.61 0.32 0.03 -0.40 -0.49 0.28 -0.42
12513 || orf19.5444 || TIM44 || || Protein involved in transport across membranes; Spider biofilm repressed || 1 -1.87 -1.77 -2.65 -2.20 -0.70 -1.32 0.26 0.71 -0.04 0.66 0.83 0.13 -0.63 -0.31 -0.28 -0.29
12514 || orf19.680 || TIM50 || || Predicted component of the Translocase of the Inner Mitochondrial membrane (TIM23 complex); involved in mitochondrial protein import; Spider biofilm repressed || 1 -2.21 -2.04 -2.97 -2.00 -1.34 -1.81 0.34 0.66 -0.25 0.59 0.64 0.03 -0.35 -0.26 -0.31 -0.35
12515 || orf19.680 || TIM50 || || Predicted component of the Translocase of the Inner Mitochondrial membrane (TIM23 complex); involved in mitochondrial protein import; Spider biofilm repressed || 1 -1.76 -1.73 -2.76 -2.40 -0.94 -1.89 0.30 0.38 -0.41 0.36 0.57 -0.14 -0.65 -0.19 -0.17 0.09
12516 || orf19.3481 || || || Putative mitochondrial ATP-dependent RNA helicase of the DEAD-box family, transcription is activated in the presence of elevated CO2 || 1 -1.75 -1.82 -2.62 -2.32 -0.95 -1.33 0.05 0.23 -0.41 0.65 0.86 0.24 -0.29 -0.23 -0.00 0.05
12517 || orf19.4261 || TIF5 || || Putative translation initiation factor; repressed upon phagocytosis by murine macrophage; Spider biofilm repressed || 1 -1.45 -1.58 -2.28 -1.71 -0.72 -0.96 0.00 0.34 -0.81 0.66 0.39 -0.09 -0.42 0.17 -0.17 -0.29
12518 || orf19.4261 || TIF5 || || Putative translation initiation factor; repressed upon phagocytosis by murine macrophage; Spider biofilm repressed || 1 -1.50 -1.49 -2.22 -1.61 -0.80 -1.03 -0.02 0.25 -0.72 0.84 0.43 -0.08 -0.36 0.07 -0.23 -0.29
12519 || orf19.7161 || SUI3 || || Putative translation initiation factor; genes encoding ribosomal subunits, translation factors, and tRNA synthetases are downregulated upon phagocytosis by murine macrophage || 1 -1.34 -1.53 -2.06 -1.61 -1.09 -1.39 -0.14 0.44 -0.59 0.68 0.80 0.04 -0.43 0.17 -0.08 -0.59
12520 || orf19.4223 || GCD11 || || Gamma subunit of translation initiation factor eIF2; involved in identification of the start codon; likely essential for growth, based on an insertional mutagenesis strategy; Spider biofilm repressed || 1 -1.52 -1.46 -2.29 -1.71 -1.08 -1.45 -0.10 0.23 -0.61 0.51 0.26 -0.12 -0.59 0.30 -0.36 0.13
12521 || orf19.4223 || GCD11 || || Gamma subunit of translation initiation factor eIF2; involved in identification of the start codon; likely essential for growth, based on an insertional mutagenesis strategy; Spider biofilm repressed || 1 -1.69 -1.76 -2.54 -1.88 -1.41 -1.58 -0.13 0.18 -0.71 0.48 0.15 -0.16 -0.91 0.06 -0.44 0.16
12522 || orf19.5081 || FUN12 || || Functional homolog of S. cerevisiae Fun12 translation initiation factor eIF5B; genes encoding ribosomal subunits, translation factors, and tRNA synthetases are downregulated upon phagocytosis by murine macrophage || 1 -1.79 -1.82 -2.12 -1.53 -1.29 -1.50 -0.44 0.18 -0.86 0.26 0.42 -0.01 -0.94 -0.50 -0.44 0.02
12523 || orf19.5081 || FUN12 || || Functional homolog of S. cerevisiae Fun12 translation initiation factor eIF5B; genes encoding ribosomal subunits, translation factors, and tRNA synthetases are downregulated upon phagocytosis by murine macrophage || 1 -2.03 -2.05 -2.69 -2.01 -1.34 -1.81 -0.50 0.11 -0.99 0.26 0.47 0.15 -1.12 -0.16 -0.45 0.14
12524 || orf19.5083 || DRG1 || || Member of the DRG family of GTP-binding proteins; involved in regulation of invasive filamentous growth || 1 -1.87 -1.87 -2.41 -1.82 -1.07 -1.09 -0.48 0.05 -0.92 0.37 0.36 -0.08 -0.89 -0.18 -0.46 -0.45
12525 || orf19.18 || IMH3 || || Inosine monophosphate (IMP) dehydrogenase; enzyme of GMP biosynthesis; target of mycophenolic acid and mizoribine monophosphate; antigenic during infection; repressed in core stress response; snoRNA snR54 encoded within IMH3 intron || 1 -2.05 -2.03 -3.14 -2.43 -1.03 -1.31 -0.46 -0.38 -1.02 0.09 0.15 -0.61 -1.39 -0.48 -0.31 0.19
12526 || orf19.18 || IMH3 || || Inosine monophosphate (IMP) dehydrogenase; enzyme of GMP biosynthesis; target of mycophenolic acid and mizoribine monophosphate; antigenic during infection; repressed in core stress response; snoRNA snR54 encoded within IMH3 intron || 1 -1.67 -1.79 -2.84 -2.22 -0.88 -1.17 -0.48 -0.22 -0.72 0.19 0.28 -0.19 -1.29 -0.39 -0.25 0.28
12527 || orf19.18 || IMH3 || || Inosine monophosphate (IMP) dehydrogenase; enzyme of GMP biosynthesis; target of mycophenolic acid and mizoribine monophosphate; antigenic during infection; repressed in core stress response; snoRNA snR54 encoded within IMH3 intron || 1 -1.45 -1.58 -2.26 -1.87 -0.59 -1.00 -0.14 -0.04 -0.77 0.35 0.48 -0.16 -1.07 -0.17 -0.16 0.20
12528 || orf19.18 || IMH3 || || Inosine monophosphate (IMP) dehydrogenase; enzyme of GMP biosynthesis; target of mycophenolic acid and mizoribine monophosphate; antigenic during infection; repressed in core stress response; snoRNA snR54 encoded within IMH3 intron || 1 -1.76 -1.67 -2.40 -2.01 -0.63 -0.88 -0.17 0.09 -0.52 0.39 0.58 0.18 -0.94 -0.16 -0.18 0.35
12529 || orf19.5541 || || || Protein with similarity to S. pombe Nrd1p; transcription induced upon induction of hyphal growth; regulated by Cph1p, Efg1p, Cph2p; low-level expression; alkaline upregulated; fungal-specific (no human or murine homolog) || 1 -1.66 -1.56 -2.40 -1.69 -0.94 -0.71 -0.48 -0.26 -1.19 0.12 0.26 -0.02 -0.43 0.01 -0.32 -0.04
12530 || orf19.2790 || SWD2 || || Ortholog(s) have histone methyltransferase activity (H3-K4 specific) activity || 1 -0.86 -0.94 -1.36 -1.03 -0.68 -0.86 -0.06 0.10 -0.40 -0.23 0.32 0.18 -0.39 -0.14 -0.20 0.32
12531 || orf19.3577 || COQ5 || || Putative methyltransferase of ubiquinone biosynthesis; regulated by Gcn4; repressed by amino acid starvation (3-AT), Hap43; induced upon adherence to polystyrene; Spider biofilm repressed || 1 -1.21 -1.49 -1.84 -1.88 -0.66 -1.39 0.30 0.40 -0.10 -0.15 0.46 0.06 -1.02 -0.25 -0.40 0.13
12532 || orf19.437 || GRS1 || || Putative tRNA-Gly synthetase; genes encoding ribosomal subunits, translation factors, tRNA synthetases are downregulated upon phagocytosis by murine macrophage; stationary phase enriched protein || 1 -1.57 -1.49 -1.94 -1.77 -0.83 -1.08 0.24 0.03 -0.00 -0.13 0.40 0.37 -0.99 -0.05 -0.51 0.21
12533 || orf19.5641 || CAR2 || || Ornithine aminotransferase; arginine metabolism; alkaline induced; mutant sensitivite to toxic ergosterol analog, to amphotericin B; exponential and stationary phase yeast; flow model biofilm induced; rat catheter, Spider biofilm repressed || 1 -2.30 -2.39 -3.05 -2.84 -1.06 -1.55 0.06 0.45 -0.16 0.14 0.82 0.82 -1.78 -0.34 -1.06 0.33
12534 || orf19.5641 || CAR2 || || Ornithine aminotransferase; arginine metabolism; alkaline induced; mutant sensitivite to toxic ergosterol analog, to amphotericin B; exponential and stationary phase yeast; flow model biofilm induced; rat catheter, Spider biofilm repressed || 1 -2.48 -2.55 -3.04 -2.91 -1.48 -1.57 -0.13 0.25 -0.18 0.10 0.71 0.63 -1.85 -0.61 -1.37 0.28
12535 || orf19.1736 || || || Protein of unknown function; transcript detected on high-resolution tiling arrays || 1 -1.64 -1.79 -1.88 -1.86 -1.25 -1.30 -0.25 -0.11 -0.25 0.27 0.34 0.12 -0.97 -0.69 -1.06 0.34
12536 || orf19.5328 || GCN1 || || Ortholog(s) have role in regulation of translational elongation and cytosolic ribosome, extracellular region, mitochondrion localization || 1 -0.95 -1.03 -1.29 -0.95 -0.56 -0.81 -0.24 0.04 0.02 0.20 0.23 0.13 -0.74 -0.14 -0.54 0.32
12537 || orf19.437 || GRS1 || || Putative tRNA-Gly synthetase; genes encoding ribosomal subunits, translation factors, tRNA synthetases are downregulated upon phagocytosis by murine macrophage; stationary phase enriched protein || 1 -1.65 -1.57 -1.64 -1.31 -0.87 -1.01 0.14 0.08 -0.50 -0.25 0.31 0.22 -1.05 -0.05 -0.96 0.00
12538 || orf19.3167 || || || Heme A:farnesyltransferase; catalyzes the 1st step in conversion of protoheme to the heme A prosthetic group required for cytochrome c oxidase activity; Spider biofilm repressed || 1 -1.38 -1.67 -1.32 -1.43 -1.35 -0.91 -0.17 -0.07 -0.03 0.10 -0.11 -0.02 -1.17 0.10 -0.48 -0.21
12539 || orf19.3400 || COQ3 || || Protein with a predicted role in coenzyme Q biosynthesis; transcriptionally induced by interaction with macrophages; possibly an essential gene, disruptants not obtained by UAU1 method || 1 -0.98 -0.91 -1.04 -1.09 -0.90 -0.54 -0.37 0.04 -0.09 0.07 -0.19 0.02 -0.73 0.19 -0.32 0.21
12540 || orf19.4395 || || || Putative actin cytoskeleton component; protein present in exponential and stationary growth phase yeast cultures || 1 -0.67 -0.74 -0.91 -0.97 -0.69 -0.71 0.05 -0.06 -0.16 -0.29 -0.03 0.19 -0.53 0.22 -0.32 0.23
12541 || orf19.2101 || || || Ortholog(s) have protein anchor activity, role in protein insertion into ER membrane, retrograde vesicle-mediated transport, Golgi to ER and GET complex, mitochondrion localization || 1 -0.99 -1.05 -1.30 -1.24 -0.91 -0.77 -0.04 0.12 -0.21 -0.15 0.21 0.25 -0.62 0.11 -0.30 0.22
12542 || orf19.7076 || GBP2 || || Putative single-strand telomeric DNA-binding protein; protein level decreases in stationary phase cultures; Spider biofilm repressed || 1 -2.08 -2.05 -2.11 -1.85 -1.89 -1.53 -0.22 -0.11 -0.53 -0.51 0.29 -0.06 -0.91 -0.03 -0.52 0.24
12543 || orf19.7076 || GBP2 || || Putative single-strand telomeric DNA-binding protein; protein level decreases in stationary phase cultures; Spider biofilm repressed || 1 -1.75 -1.90 -1.71 -1.89 -1.78 -1.58 -0.12 -0.03 -0.53 -0.29 0.26 -0.15 -0.76 0.01 -0.79 0.27
12544 || orf19.2178 || MRS4 || || Mitochondrial carrier family member, involved in iron homeostasis; putative membrane transporter localized to the mitochondrial membrane; transcription under control of Atf2p; regulated by Sef1p, Sfu1p, and Hap43p || 1 -1.55 -1.67 -1.79 -1.74 -1.54 -1.15 -0.50 -0.14 -0.17 0.13 0.23 0.09 -0.51 0.19 -0.33 -0.09
12545 || orf19.2178 || MRS4 || || Mitochondrial carrier family member, involved in iron homeostasis; putative membrane transporter localized to the mitochondrial membrane; transcription under control of Atf2p; regulated by Sef1p, Sfu1p, and Hap43p || 1 -0.81 -1.42 -1.38 -1.71 -1.31 -1.33 -0.55 -0.17 -0.06 -0.00 0.10 0.11 -0.43 0.26 -0.39 -0.06
12546 || orf19.5861 || KRE9 || || Protein of beta-1,6-glucan biosynthesis; required for serum-induced hyphal growth; required for efficient utilization of galactose and for growth on glucose; similar to S. cerevisiae Kre9p and Knh1p; O-glycosylated by Pmt1p || 1 -0.82 -0.96 -1.21 -0.87 -0.85 -1.10 -0.48 -0.04 -0.41 -0.08 0.13 0.07 -0.52 0.04 -0.53 -0.07
12547 || orf19.978 || BDF1 || || Bromodomain transcription factor; repressed upon adherence to polystyrene; reduced mRNA abundance detected in null mutant; macrophage/pseudohyphal-repressed; possibly essential, disruptants not obtained by UAU1 method || 1 -1.23 -1.07 -1.15 -1.17 -0.93 -0.99 -0.49 -0.15 -0.71 -0.35 0.09 0.13 -0.30 0.01 -0.34 -0.08
12548 || orf19.3873 || ARC40 || || Protein similar to S. cerevisiae Arc40; involved in actin filament organization in S. cerevisiae; transposon mutation affects filamentous growth; rat catheter and Spider biofilm repressed || 1 -1.03 -0.81 -1.07 -0.86 -0.61 -0.59 -0.03 -0.15 -0.38 -0.29 0.27 0.00 -0.75 -0.29 -0.11 -0.18
12549 || orf19.3177 || || || Ortholog(s) have 2,5-diamino-6-ribitylamino-4(3H)-pyrimidinone 5'-phosphate deaminase activity, pseudouridine synthase activity, role in riboflavin biosynthetic process, tRNA pseudouridine synthesis and cytosol localization || 1 -1.19 -1.24 -1.44 -1.41 -0.53 -0.97 -0.17 -0.19 -0.13 -0.39 0.25 -0.06 -0.93 -0.36 -0.26 -0.09
12550 || orf19.2101 || || || Ortholog(s) have protein anchor activity, role in protein insertion into ER membrane, retrograde vesicle-mediated transport, Golgi to ER and GET complex, mitochondrion localization || 1 -0.91 -1.03 -1.47 -1.49 -1.03 -1.11 -0.15 -0.11 -0.50 -0.47 0.16 -0.15 -0.64 -0.23 -0.51 -0.02
12551 || orf19.3055 || MED17 || || Putative RNA polymerase II mediator complex subunit; possibly an essential gene, disruptants not obtained by UAU1 method || 1 -1.46 -1.57 -1.83 -1.88 -1.13 -1.43 -0.31 -0.51 -0.86 -0.45 -0.12 -0.10 -0.76 -0.79 -0.35 -0.00
12552 || orf19.1323 || || || Phosphorylated protein of unknown function; Hap43p-repressed gene || 1 -0.98 -1.15 -1.39 -1.28 -1.29 -0.79 -0.42 -0.51 -0.52 -0.33 -0.01 -0.43 -0.50 -0.28 -0.27 0.05
12553 || orf19.2115 || || || Putative molybdopterin-converting factor; fungal-specific (no human or murine homolog) || 1 -1.49 -1.51 -1.95 -1.65 -1.65 -1.39 -0.56 -0.13 -0.77 0.06 0.25 -0.41 -0.79 -0.52 -0.18 -0.09
12554 || orf19.18 || IMH3 || || Inosine monophosphate (IMP) dehydrogenase; enzyme of GMP biosynthesis; target of mycophenolic acid and mizoribine monophosphate; antigenic during infection; repressed in core stress response; snoRNA snR54 encoded within IMH3 intron || 1 -2.16 -2.23 -3.11 -2.53 -1.12 -1.64 -0.67 -0.34 -1.32 -0.01 0.05 -0.89 -1.92 -0.69 -0.80 -0.32
12555 || orf19.6060 || GCN20 || || YEF3-subfamily ABC family protein, predicted not to be a transporter || 1 -1.46 -1.42 -1.83 -1.32 -0.93 -1.17 -0.60 -0.12 -0.79 0.04 -0.09 -0.45 -1.22 -0.49 -0.82 -0.63
12556 || orf19.3941 || URA7 || || CTP synthase 1; flucytosine induced; protein present in exponential and stationary growth phase yeast cultures || 1 -1.18 -1.15 -1.92 -1.58 -1.32 -1.11 -0.30 0.02 -0.69 0.29 0.01 -0.53 -1.19 -0.36 -0.84 -0.21
12557 || orf19.4641 || NMT1 || || Myristoyl-CoA:protein N-myristoyltransferase; attaches the fatty acid myristate to a small number of proteins at an N-terminal Gly; essential; antifungal drug target; functional homolog of S. cerevisiae Nmt1p || 1 -1.33 -1.67 -2.00 -1.74 -1.41 -1.63 -0.37 -0.17 -1.11 -0.02 0.24 -0.23 -1.06 -0.35 -0.81 -0.33
12558 || orf19.5682 || || || Ortholog(s) have protein binding, bridging, protein transporter activity and role in chromosome condensation, protein import into nucleus, protein targeting to membrane, regulation of mitotic cell cycle || 1 -1.14 -1.26 -1.28 -1.10 -1.06 -1.02 -0.63 -0.29 -0.87 -0.10 -0.29 -0.39 -1.00 -0.60 -0.60 -0.18
12559 || orf19.1514 || || || Ortholog(s) have enzyme binding, phosphatidylinositol-4-phosphate binding activity and role in endoplasmic reticulum unfolded protein response, protein localization to Golgi apparatus, retrograde vesicle-mediated transport, Golgi to ER || 1 -0.61 -0.80 -1.18 -0.98 -0.88 -1.01 -0.33 -0.06 -0.25 0.17 0.19 0.11 -0.47 -0.47 -0.17 -0.17
12560 || orf19.536 || || || Ortholog(s) have chromatin binding, protein complex scaffold, ubiquitin binding activity and role in histone acetylation, transcription from RNA polymerase II promoter || 1 -0.68 -0.61 -0.82 -0.65 -0.76 -0.76 -0.27 -0.19 -0.36 0.10 0.35 0.22 -0.25 -0.19 -0.12 0.08
12561 || orf19.5887 || NUP85 || || Ortholog of S. cerevisiae Nup85; a structural constituent of the nuclear pore; required for alkaline-induced hyphal morphogenesis and for SD or Spider media biofilm formation || 1 -0.74 -0.84 -1.06 -0.98 -0.66 -0.58 -0.30 -0.37 -0.49 -0.01 0.22 0.35 -0.35 -0.00 -0.48 0.09
12562 || orf19.2213 || || || Ortholog(s) have cytoplasm, nucleus localization || 1 -0.69 -0.81 -1.30 -0.94 -0.80 -0.75 -0.04 -0.40 -0.40 -0.15 -0.16 0.26 -0.33 0.15 -0.25 0.03
12563 || orf19.1119 || MTR10 || || Putative importin; member of a family of fungal-specific nuclear importins; Mig1-regulated || 1 -0.85 -0.89 -0.98 -0.90 -0.64 -0.60 -0.31 -0.42 -0.35 0.06 -0.10 0.29 -0.32 0.13 0.06 -0.01
12564 || orf19.6029 || ROT1 || || Similar to S. cerevisiae Rot1p, which is involved in cell wall 1,6-beta-glucan biosynthesis; has predicted transmembrane region; possibly an essential gene, disruptants not obtained by UAU1 method || 1 -1.48 -1.52 -1.75 -1.67 -1.40 -0.87 -0.51 -0.43 -1.17 -0.12 -0.12 0.22 -0.19 0.16 0.06 0.05
12565 || orf19.978 || BDF1 || || Bromodomain transcription factor; repressed upon adherence to polystyrene; reduced mRNA abundance detected in null mutant; macrophage/pseudohyphal-repressed; possibly essential, disruptants not obtained by UAU1 method || 1 -0.97 -0.80 -1.25 -1.26 -0.57 -0.56 -0.17 -0.21 -0.39 -0.09 0.30 -0.09 0.03 0.13 -0.09 0.06
12566 || orf19.5381 || || || Ortholog(s) have mRNA binding activity || 1 -1.12 -1.17 -1.80 -1.78 -0.42 -0.69 -0.46 -0.21 -0.85 -0.25 -0.02 -0.07 -0.40 0.03 -0.16 -0.23
12567 || orf19.6904 || GCN3 || || Putative translation initiator; downregulated in the presence of human whole blood or polymorphonuclear (PMN) cells || 1 -0.64 -0.71 -1.02 -1.03 -0.55 -0.48 -0.13 0.14 -0.27 0.28 0.11 -0.14 -0.37 0.29 -0.33 -0.15
12568 || orf19.3792 || || || Ortholog(s) have role in cytoplasmic mRNA processing body assembly, deadenylation-dependent decapping of nuclear-transcribed mRNA, formation of translation preinitiation complex, negative regulation of translational initiation || 1 -1.19 -1.28 -1.52 -1.53 -1.20 -1.21 0.06 0.13 -0.36 -0.31 0.41 0.17 -0.33 -0.12 -0.35 -0.62
12569 || orf19.7655 || RPO21 || || RNA polymerase II; ortholog of S. cerevisiae Rpo21, transposon mutation affects filamentous growth; flow model biofilm repressed || 1 -0.84 -0.95 -1.31 -1.00 -0.67 -1.37 -0.09 -0.00 -0.43 -0.38 0.31 -0.10 -0.36 -0.52 -0.18 -0.01
12570 || orf19.3946 || || || Ortholog(s) have membrane insertase activity, role in protein insertion into mitochondrial membrane from inner side, respiratory chain complex IV assembly and integral to mitochondrial inner membrane localization || 1 -0.59 -0.72 -0.66 -0.88 -0.44 -0.86 -0.09 -0.00 -0.08 -0.19 0.17 0.01 -0.42 -0.29 0.03 0.04
12571 || orf19.3123.2 || || || Ortholog(s) have cytidine deaminase activity, role in cytidine catabolic process, deoxycytidine catabolic process, pyrimidine-containing compound salvage and cytosol, nucleus localization || 1 -0.82 -1.09 -1.36 -1.23 -0.99 -1.31 0.10 0.02 -0.14 -0.16 0.23 0.13 -0.20 -0.55 0.20 0.10
12572 || orf19.7323 || CBP1 || || Corticosteroid binding protein; transcription induced at late log-phase or upon adherence to polystyrene; not induced by corticosterone; contains a possible NAD/FAD binding region; regulated by Nrg1, Tup1; Spider biofilm induced || 1 -1.55 -1.59 -2.53 -1.97 -0.80 -1.11 0.19 0.07 0.25 -0.19 -0.18 -0.52 -1.27 -0.63 -1.11 0.30
12573 || orf19.1195 || || || Ortholog(s) have metalloendopeptidase activity, role in cellular iron ion homeostasis, protein processing involved in protein targeting to mitochondrion and mitochondrion localization || 1 -1.21 -1.02 -1.28 -1.34 -0.42 -0.46 0.07 0.08 0.22 0.08 -0.33 0.19 -0.53 -0.07 -0.30 0.06
12574 || orf19.3167 || || || Heme A:farnesyltransferase; catalyzes the 1st step in conversion of protoheme to the heme A prosthetic group required for cytochrome c oxidase activity; Spider biofilm repressed || 1 -0.87 -0.99 -0.71 -0.76 -0.95 -1.09 -0.27 -0.05 0.20 0.14 -0.38 0.08 -0.55 -0.31 -0.54 -0.20
12575 || orf19.3249 || LAG1 || || Putative ceramide synthase component; Hap43p-repressed gene; amphotericin B repressed || 1 -1.24 -1.47 -0.80 -0.57 -1.88 -1.78 -0.65 -0.19 -0.47 0.03 -0.19 -0.22 -1.21 -0.55 -1.21 -0.18
12576 || orf19.1659 || ALG8 || || Putative glucosyltransferase involved in cell wall mannan biosynthesis; transcription is elevated in nik1 and sln1 homozygous null mutants, but not in the chk1 null mutant; possibly an essential gene, disruptants not obtained by UAU1 method || 1 -1.38 -1.48 -0.92 -0.56 -1.52 -1.28 -0.46 -0.41 -0.36 -0.12 -0.52 -0.06 -0.73 -0.22 -0.64 -0.17
12577 || orf19.7100 || || || Putative vacuolar transporter of large neutral amino acids; possibly transcriptionally regulated upon hyphal formation; not the true Avt1 ortholog of S. cerevisiae || 1 -2.39 -2.52 -1.64 -0.85 -2.28 -2.03 -0.74 -0.31 -0.61 -0.32 0.17 -0.13 -0.99 -0.52 -1.49 -0.13
12578 || orf19.5321 || || || Ortholog(s) have methylenetetrahydrofolate reductase (NAD(P)H) activity and role in methionine biosynthetic process, one-carbon metabolic process || 1 -1.10 -1.05 -0.84 -0.68 -0.92 -1.18 -0.83 -0.16 -0.23 -0.35 0.12 -0.09 -0.75 -0.12 -0.83 -0.22
12579 || orf19.4293 || || || Ortholog(s) have role in iron-sulfur cluster assembly, ribosomal large subunit export from nucleus, tRNA wobble uridine modification and cytosol, nucleus localization || 1 -0.82 -0.94 -0.60 -0.67 -1.03 -0.61 -0.28 -0.30 -0.14 -0.09 0.15 -0.31 -0.62 -0.05 -0.79 0.00
12580 || orf19.7136 || SPT6 || || Putative transcription elongation factor; transposon mutation affects filamentous growth; transcript induced in an RHE model of oral candidiasis and in clinical isolates from oral candidiasis || 1 -0.97 -1.22 -0.81 -0.63 -0.75 -0.64 -0.46 -0.12 -0.23 -0.11 -0.01 0.13 -1.08 -0.18 -0.70 0.23
12581 || orf19.5682 || || || Ortholog(s) have protein binding, bridging, protein transporter activity and role in chromosome condensation, protein import into nucleus, protein targeting to membrane, regulation of mitotic cell cycle || 1 -1.30 -1.27 -0.87 -1.02 -1.15 -0.77 -0.53 -0.34 -0.41 0.13 -0.44 0.06 -1.05 0.06 -0.62 -0.03
12582 || orf19.5693 || || || Subunit of the GPI (glycosylphosphatidylinositol):protein transamidase complex; removes the GPI-anchor signal and attaches GPI to proteins in the ER; Spider biofilm repressed || 1 -1.61 -1.55 -0.68 -0.70 -1.03 -0.73 -0.46 -0.22 -0.24 0.36 -0.35 -0.17 -1.21 0.03 -1.09 0.00
12583 || orf19.7579 || FGR34 || || Protein lacking an ortholog in S. cerevisiae; transposon mutation affects filamentous growth || 1 -0.91 -0.92 -0.41 -0.43 -0.64 -0.56 -0.35 -0.25 -0.42 -0.28 -0.42 -0.25 -0.84 0.08 -0.57 0.00
12584 || orf19.6984 || || || Ortholog of C. dubliniensis CD36 : Cd36_85460, C. parapsilosis CDC317 : CPAR2_405760, Candida tenuis NRRL Y-1498 : CANTEDRAFT_116052 and Debaryomyces hansenii CBS767 : DEHA2D16940g || 1 -1.60 -1.37 -1.31 -0.76 -1.06 -0.92 -0.43 -0.53 -0.32 0.39 -0.74 -0.00 -0.54 -0.17 -0.63 -0.85
12585 || orf19.7392 || DED1 || || Predicted ATP-dependent RNA helicase; RNA strand annealing activity; Spider biofilm induced || 1 -1.23 -1.22 -1.63 -0.75 -1.43 -1.35 -0.22 -0.25 -0.82 0.45 -0.61 -0.65 -0.40 0.06 -0.43 -0.46
12586 || orf19.825 || GCD7 || || Putative translation initiator; downregulated in the presence of human whole blood or polymorphonuclear (PMN) cells || 1 -1.06 -1.02 -0.96 -1.14 -0.81 -1.15 -0.29 -0.39 -0.60 0.26 -0.27 -0.39 -0.50 -0.12 -0.49 -0.27
12587 || orf19.5085 || || || Ortholog(s) have nuclear localization sequence binding, protein transporter activity and role in mRNA export from nucleus, protein import into nucleus, regulation of mitosis, regulation of protein desumoylation || 1 -1.15 -1.05 -1.23 -0.84 -0.87 -1.06 -0.51 -0.03 -0.87 0.38 -0.20 -0.50 -0.86 -0.14 -0.70 -0.14
12588 || orf19.2318.1 || || || Ortholog(s) have inositol phosphoceramide synthase regulator activity, role in inositolphosphoceramide metabolic process and inositol phosphoceramide synthase complex, integral to Golgi membrane localization || 1 -1.24 -1.14 -1.30 -0.68 -1.09 -1.36 -0.71 -0.09 -0.43 0.40 -0.37 -0.61 -0.52 -0.45 -0.80 -0.65
12589 || orf19.943 || FET33 || || Putative multicopper ferro-O2-oxidoreductase; repressed in core caspofungin response; fails to complement S. cerevisiae fet3 iron-related phenotypes; rat catheter and Spider biofilm induced || 1 -1.10 -1.51 -1.93 -1.02 -1.24 -1.65 -0.31 -0.10 -0.31 0.35 -0.28 -0.60 -1.20 -0.41 -0.89 -0.63
12590 || orf19.3400 || COQ3 || || Protein with a predicted role in coenzyme Q biosynthesis; transcriptionally induced by interaction with macrophages; possibly an essential gene, disruptants not obtained by UAU1 method || 1 -0.97 -1.18 -1.32 -0.77 -0.96 -0.81 -0.38 -0.18 -0.07 -0.17 -0.21 -0.46 -0.62 -0.31 -0.67 -0.27
12591 || orf19.2318.1 || || || Ortholog(s) have inositol phosphoceramide synthase regulator activity, role in inositolphosphoceramide metabolic process and inositol phosphoceramide synthase complex, integral to Golgi membrane localization || 1 -1.08 -1.37 -1.12 -0.82 -0.96 -0.78 -0.55 -0.09 -0.24 0.54 -0.20 -0.11 -0.47 0.20 -0.60 -0.27
12592 || orf19.2183 || KRE30 || || YEF3-subfamily ABC family protein; predicted not to be a transporter; repressed in core stress response; mutation confers hypersensitivity to amphotericin B || 1 -1.48 -1.54 -1.69 -1.76 -1.32 -1.26 -0.50 -0.03 -0.95 0.71 0.04 -0.42 -0.30 0.40 -1.32 -0.37
12593 || orf19.6008.3 || || || Ortholog of C. dubliniensis CD36 : Cd36_00920, Debaryomyces hansenii CBS767 : DEHA2F20724g, Pichia stipitis Pignal : PICST_32745 and Candida albicans WO-1 : CAWG_01277 || 1 -0.94 -1.06 -0.55 -0.87 -0.65 -0.63 -0.29 -0.27 -0.51 -0.39 -0.32 -0.14 -0.36 0.04 -0.61 -0.49
12594 || orf19.5401 || || || Putative adhesin-like protein; mutation confers hypersensitivity to toxic ergosterol analog; decreased transcription is observed upon fluphenazine treatment; overlaps orf19.5402; merged with orf19.5404 into orf19.5404.1 || 1 -0.87 -0.77 -0.83 -0.83 -0.71 -0.52 -0.01 -0.27 -0.16 -0.46 -0.41 -0.46 -0.45 0.09 -0.43 -0.04
12595 || orf19.7363 || KRE6 || || Essential beta-1,6-glucan synthase subunit; change in mRNA length, not abundance, at yeast-hypha transition; alkaline induced by Rim101, on cell wall regeneration; Spider biofilm induced; Bcr1-repressed in RPMI a/a biofilms || 1 -1.58 -1.74 -1.47 -1.46 -1.24 -0.94 -0.33 -0.84 -0.94 -0.58 -0.46 -0.75 -0.04 -0.26 -0.76 -0.38
12596 || orf19.4521 || || || S. cerevisiae ortholog Env9 has similarity to oxidoreductases and is proposed to have vacuolar functions, found in lipid particles; hyphal-induced expression || 1 -1.30 -1.21 -1.46 -1.66 -1.17 -1.35 -0.20 -0.40 -0.58 -0.95 -0.17 -0.25 0.29 0.19 -0.50 -0.41
12597 || orf19.839 || || || Putative endoribonuclease; induced by nitric oxide independent of Yhb1p; mutation confers hypersensitivity to aureobasidin A || 1 -1.15 -1.30 -1.81 -1.90 -1.22 -1.53 -0.40 -0.60 -0.64 -0.61 -0.26 -0.40 -0.59 -0.01 -0.80 -0.41
12598 || orf19.568 || SPE2 || || Putative S-adenosylmethionine decarboxylase; Hap43-induced gene; possibly adherence-induced; Spider biofilm induced || 1 -1.23 -1.19 -1.81 -1.55 -1.27 -1.33 -0.24 -0.60 -0.66 -0.52 -0.75 -0.23 -0.50 -0.16 -0.48 -0.92
12599 || orf19.568 || SPE2 || || Putative S-adenosylmethionine decarboxylase; Hap43-induced gene; possibly adherence-induced; Spider biofilm induced || 1 -1.01 -0.94 -1.69 -1.14 -1.17 -0.93 -0.08 -0.52 -0.41 -0.20 -0.66 0.09 -0.24 0.02 -0.43 -0.56
12600 || orf19.1968.1 || || || Predicted non-catalytic subunit of N-terminal acetyltransferase; Spider biofilm induced || 1 -2.57 -2.30 -2.55 -1.99 -1.72 -1.56 -0.10 -0.66 -0.52 -0.33 -0.89 0.25 -0.18 0.20 -1.10 -0.46
12601 || orf19.1968.1 || || || Predicted non-catalytic subunit of N-terminal acetyltransferase; Spider biofilm induced || 1 -2.13 -2.63 -2.19 -2.24 -1.88 -1.61 0.03 -0.56 -0.26 -0.15 -0.84 -0.52 -0.04 -0.05 -1.20 -0.74
12602 || orf19.5496 || AVT1 || || Putative vacuolar transporter; promoter bound by a1p and alpha2p by ChIP-chip analysis || 1 -2.28 -2.36 -1.87 -2.12 -2.26 -2.24 0.07 -0.24 -0.07 -0.29 -0.19 -0.42 -0.20 -0.05 -0.78 -0.15
12603 || orf19.511 || || || Ortholog(s) have ribosylnicotinamide kinase activity, role in NAD biosynthesis via nicotinamide riboside salvage pathway, nicotinamide riboside metabolic process and cytosol, nucleus localization || 1 -1.59 -1.52 -1.34 -1.17 -1.79 -1.31 -0.29 -0.21 -0.48 -0.51 -0.25 -0.22 -0.73 -0.44 -0.43 0.00
12604 || orf19.5643 || ECM7 || || Protein involved in control of calcium homeostasis and oxidative stress response; mutants show defects in hyphal growth || 1 -1.10 -1.39 -1.04 -1.21 -1.17 -0.54 -0.28 -0.34 -0.34 -0.70 -0.08 -0.06 -0.72 -0.10 -0.38 0.02
12605 || orf19.2106 || || || Putative protein of unknown function; Hap43p-repressed gene || 1 -0.63 -0.79 -0.76 -0.83 -0.60 -0.39 -0.30 -0.27 -0.08 -0.44 -0.27 -0.05 -0.45 -0.13 -0.24 0.30
12606 || orf19.791 || RIM11 || || Ortholog of S. cerevisiae Rim11; a protein kinase involved in meiosis and sporulation in S. cerevisiae; mutant is viable || 1 -0.66 -0.90 -0.87 -1.00 -0.75 -0.56 -0.26 -0.41 -0.06 -0.54 -0.29 -0.07 -0.32 -0.23 -0.17 0.09
12607 || orf19.5854 || SBP1 || || Similar to RNA binding proteins; downregulated upon adherence to polystyrene; stationary-phase enriched protein || 1 -1.21 -1.27 -1.29 -1.49 -0.95 -0.53 -0.28 -0.77 -0.25 -0.73 -0.38 -0.03 -0.36 0.01 -0.70 0.10
12608 || orf19.5854 || SBP1 || || Similar to RNA binding proteins; downregulated upon adherence to polystyrene; stationary-phase enriched protein || 1 -0.98 -0.99 -0.89 -0.88 -1.01 -0.25 -0.15 -0.60 -0.07 -0.81 -0.37 -0.04 -0.32 -0.20 -0.55 0.13
12609 || orf19.791 || RIM11 || || Ortholog of S. cerevisiae Rim11; a protein kinase involved in meiosis and sporulation in S. cerevisiae; mutant is viable || 1 -1.26 -1.29 -1.00 -0.94 -0.95 -0.56 -0.73 -0.80 -0.25 -0.76 -0.67 -0.15 -0.50 -0.46 -0.47 -0.14
12610 || orf19.5897 || || || Ortholog(s) have Seh1-associated complex, cytosol, extrinsic to fungal-type vacuolar membrane localization || 1 -0.92 -1.11 -0.98 -0.87 -0.90 -0.75 -0.50 -0.70 -0.25 -0.32 -0.56 -0.36 -0.58 -0.46 -0.22 -0.06
12611 || orf19.438 || || || Ortholog of S. cerevisiae : YHR078W, C. glabrata CBS138 : CAGL0J10626g, C. dubliniensis CD36 : Cd36_05020, Candida tenuis NRRL Y-1498 : CANTEDRAFT_95811 and Debaryomyces hansenii CBS767 : DEHA2E07524g || 1 -2.18 -2.32 -1.84 -1.68 -1.53 -1.15 -0.72 -0.57 -0.44 -0.31 -0.74 0.01 -0.82 -0.65 -0.50 -0.09
12612 || orf19.2012 || NOT3 || || Transcriptional regulator; not required for buccal epithelial cell adherence or virulence in mouse systemic infection; null mutant colonies exhibit slightly decreased filamentation ratio; required for yeast adherence to silicone substrate || 1 -1.38 -1.57 -1.23 -0.99 -1.21 -1.01 -0.80 -0.68 -0.29 -0.14 -0.19 -0.02 -0.35 -0.16 -0.60 -0.21
12613 || orf19.1210 || || || Ortholog(s) have L-arginine transmembrane transporter activity, L-aspartate transmembrane transporter activity and L-glutamate transmembrane transporter activity, more || 1 -2.24 -2.46 -1.77 -2.05 -1.91 -1.42 -0.44 -0.46 -0.44 -0.52 -0.20 0.26 -0.03 -0.08 -0.11 0.41
12614 || orf19.1268 || || || Protein of unknown function; transcript detected on high-resolution tiling arrays; rat catheter biofilm induced || 1 -1.43 -1.76 -0.98 -0.94 -1.55 -0.46 -0.75 -0.27 -0.65 -0.08 -0.12 -0.12 -0.32 -0.09 -0.86 -0.05
12615 || orf19.5321 || || || Ortholog(s) have methylenetetrahydrofolate reductase (NAD(P)H) activity and role in methionine biosynthetic process, one-carbon metabolic process || 1 -1.00 -0.97 -0.77 -0.78 -0.50 -0.80 -0.53 -0.12 -0.25 -0.06 0.35 0.04 -0.44 -0.02 -0.59 0.01
12616 || orf19.4940 || || || Putative histidine permease; fungal-specific (no human or murine homolog); Hap43p-induced gene || 1 -2.16 -2.49 -3.15 -2.04 -2.54 -3.03 -0.97 -0.54 0.28 0.47 0.12 0.20 -2.89 -0.16 -0.37 -0.48
12617 || orf19.7566 || || || Predicted amino acid transport domain; transcript upregulated in clinical strains from HIV+ patients with oral candidiasis; alkaline upregulated by Rim101; rat catheter, Spider and flow model biofilm induced || 1 -1.18 -1.19 -1.79 -1.74 -1.43 -1.79 -0.29 -0.73 0.25 0.15 -0.28 0.15 -1.15 0.15 -0.44 0.02
12618 || orf19.2042 || || || Ortholog(s) have role in mitochondrial tRNA wobble uridine modification and mitochondrial inner membrane localization || 1 -0.76 -0.79 -0.93 -0.84 -0.92 -0.61 -0.22 -0.10 -0.12 0.33 -0.03 -0.02 -0.33 0.02 -0.31 0.50
12619 || orf19.5852 || || || Protein of unknown function; rat catheter biofilm repressed || 1 -0.86 -0.98 -1.07 -0.38 -0.51 -0.75 -0.23 -0.20 -0.44 -0.31 0.05 0.18 -0.70 0.20 -0.30 0.06
12620 || orf19.3247 || || || Putative ortholog of S. cerevisiae Laa1p; likely to be essential for growth, based on an insertional mutagenesis strategy || 1 -0.54 -0.63 -0.53 -0.61 -0.71 -1.04 -0.28 -0.35 -0.25 -0.09 0.02 0.03 -0.68 -0.04 -0.37 0.22
12621 || orf19.2012 || NOT3 || || Transcriptional regulator; not required for buccal epithelial cell adherence or virulence in mouse systemic infection; null mutant colonies exhibit slightly decreased filamentation ratio; required for yeast adherence to silicone substrate || 1 -0.76 -0.71 -0.93 -0.90 -0.57 -0.93 -0.48 -0.34 -0.12 0.12 -0.17 0.21 -0.41 0.10 -0.50 0.03
12622 || orf19.5209 || || || Ortholog(s) have role in CVT pathway, intra-Golgi vesicle-mediated transport and Golgi transport complex, cell division site, cytosol, nucleus localization || 1 -0.66 -0.53 -0.99 -1.05 -0.78 -0.94 -0.34 -0.24 -0.30 -0.04 -0.09 0.33 -0.46 0.32 -0.38 0.25
12623 || orf19.6036 || RIC1 || || Ortholog of S. cerevisiae Ric1 guanyl-nucleotide exchange factor; mutant is viable; rat catheter biofilm repressed || 1 -0.51 -0.47 -0.92 -0.99 -0.63 -0.87 -0.08 -0.31 -0.03 -0.25 -0.07 0.44 -0.48 0.35 -0.16 0.33
12624 || orf19.2970 || LYS2 || || Heterodimeric alpha-aminoadipate reductase large subunit; lysine biosynthesis; predicted binding sites for AMP and alpha-aminoadipate; inhibited by lys or thialysine; regulated by Gcn2 and Gcn4; Spider biofilm induced, flow model repressed || 1 -1.19 -1.24 -1.14 -0.84 -0.90 -1.09 0.28 -0.16 0.04 -0.71 -0.07 -0.11 -0.59 -0.72 -0.05 -0.19
12625 || orf19.2781 || || || Protein with predicted serine/threonine kinase and tyrosine kinase domains; possibly an essential gene, disruptants not obtained by UAU1 method; Spider biofilm induced || 1 -1.17 -1.12 -2.27 -1.27 -0.36 -1.09 0.12 -0.52 -0.10 -0.12 -0.32 -0.07 -0.03 -1.08 -0.46 -0.59
12626 || orf19.2532 || PRS || || Putative prolyl-tRNA synthetase; monofunctional Class II synthetase; gene is constitutively expressed || 1 -1.16 -0.95 -1.78 -1.75 -0.13 -0.54 -0.30 -0.63 0.26 0.05 -0.46 0.36 -0.15 -0.44 -0.17 -0.34
12627 || orf19.4456 || GAP4 || || Putative amino acid permease; hyphal induced; regulated by Hap43, Gcn2 and Gcn4; colony morphology-related gene regulation by Ssnp; detected at plasma membrane of yeast and germ tube by mass spec; Spider biofilm induced || 1 -1.33 -1.41 -2.06 -2.33 -0.84 -0.49 0.02 -0.91 -0.00 0.13 -0.71 -0.30 -0.62 -0.60 -0.22 -0.87
12628 || orf19.1914 || FAV3 || || Putative alpha-1,6-mannanase; induced by mating factor in MTLa/MTLa opaque cells || 1 -1.03 -1.11 -0.95 -0.65 -0.22 -0.16 0.06 0.17 0.36 0.05 -0.25 -0.06 -0.20 -0.19 -0.33 -0.51
12629 || orf19.1914 || FAV3 || || Putative alpha-1,6-mannanase; induced by mating factor in MTLa/MTLa opaque cells || 1 -0.90 -1.04 -1.02 -0.90 -0.30 -0.39 -0.13 0.08 0.15 -0.32 -0.42 -0.23 -0.27 0.14 -0.36 -0.27
12630 || orf19.6432 || || || Ortholog(s) have ATPase activity, role in response to drug, ribosomal large subunit biogenesis and cytosol, preribosome, large subunit precursor localization || 1 -0.66 -0.67 -0.72 -0.56 -0.41 -0.29 -0.28 -0.11 -0.07 0.10 -0.29 -0.17 -0.44 -0.26 0.03 -0.01
12631 || orf19.6141 || HGT16 || || Putative glucose transporter of the major facilitator superfamily; the C. albicans glucose transporter family comprises 20 members; 12 probable membrane-spanning segments; gene has intron; expressed in rich medium with 2% glucose || 1 -1.96 -2.13 -2.19 -2.38 -1.23 -0.63 -0.46 -0.25 -0.15 0.46 -1.10 -1.10 -1.13 -0.44 -0.26 -0.39
12632 || orf19.4299 || MSW1 || || Protein similar to S. cerevisiae Msw1p, which is mitochondrial tryptophanyl-tRNA synthetase; Hap43p-repressed gene; likely to be essential for growth, based on an insertional mutagenesis strategy || 1 -1.38 -1.33 -1.22 -1.16 -0.40 -0.25 -0.50 -0.14 -0.08 0.44 -0.55 -0.10 -0.48 -0.20 -0.21 -0.35
12633 || orf19.698 || || || Integral ER membrane protein; predicted role in maintenance of ER zinc homeostasis; Spider biofilm induced || 1 -1.42 -1.33 -1.02 -1.06 -0.94 -0.61 -0.53 -0.40 0.07 0.06 -0.70 -0.62 -0.35 -0.23 -0.28 -0.59
12634 || orf19.3859 || || || Putative microsomal beta-keto-reductase; transcript upregulated by treatment with ciclopirox olamine; induced by alpha pheromone in SpiderM medium; regulated by Sef1, Sfu1, and Hap43 || 1 -1.32 -1.24 -1.22 -0.86 -0.45 -0.73 -0.14 -0.01 -0.27 -0.17 -0.86 -0.86 -0.83 -0.09 -0.17 -0.60
12635 || orf19.4396 || || || Mitochondrial inner membrane protein; mammalian mitofilin domain; Spider biofilm repressed || 1 -0.55 -0.61 -0.49 -0.39 -0.24 -0.24 -0.02 -0.00 0.06 0.11 -0.50 -0.45 -0.35 0.19 0.10 -0.40
12636 || orf19.3671 || || || Dubious open reading frame || 1 -1.33 -1.34 -0.87 -1.16 -0.09 -0.28 -0.60 -1.29 -0.06 -0.47 -0.16 -0.83 -0.34 0.13 -0.40 -0.29
12637 || orf19.1332 || SNG4 || || Putative membrane transporter; Hap43-induced; inducd by Mnl1p under weak acid stress; shows Mob2-dependent hyphal regulation || 1 -0.89 -1.04 -0.47 -0.73 -0.22 0.18 -0.61 -0.46 -0.40 0.13 -0.39 0.05 -0.44 -0.14 -0.11 -0.59
12638 || orf19.1163 || || || Has domain(s) with predicted GTP binding activity || 1 -1.23 -0.94 -0.62 -0.72 -0.12 0.01 -0.17 -0.39 -0.07 -0.10 -0.28 -0.13 -0.37 -0.65 -0.16 -0.43
12639 || orf19.4553 || || || Ortholog of C. dubliniensis CD36 : Cd36_64990, C. parapsilosis CDC317 : CPAR2_600170, Candida tenuis NRRL Y-1498 : CANTEDRAFT_121753 and Debaryomyces hansenii CBS767 : DEHA2E19712g || 1 -1.66 -1.82 -0.89 -1.15 -0.30 0.05 -0.61 -0.63 0.01 -0.07 -0.36 0.37 0.17 -0.67 -0.14 -0.42
12640 || orf19.6522 || || || Putative allantoate permease; Gcn4-regulated; Spider biofilm induced || 1 -1.51 -1.23 -0.52 -0.60 -0.15 0.21 -0.71 -0.86 0.62 -0.24 -1.12 0.23 0.03 -0.27 -0.14
12641 || orf19.6522 || || || Putative allantoate permease; Gcn4-regulated; Spider biofilm induced || 1 -1.60 -1.33 -0.84 -1.07 -0.12 -0.08 -0.81 -0.88 -0.00 -0.65 -1.04 -0.84 -0.00 -0.31 -0.34 -0.29
12642 || orf19.6719 || || || Putative nucleosome assembly protein; homozygous transposon insertion causes decreased colony wrinkling under filamentous growth-inducing conditions, but does not block true hyphal formation in liquid media || 1 -0.41 -0.55 -0.44 -0.50 -0.19 -0.11 -0.62 -0.38 0.03 -0.05 -0.40 -0.03 -0.26 -0.08 -0.26 -0.09
12643 || orf19.4553 || || || Ortholog of C. dubliniensis CD36 : Cd36_64990, C. parapsilosis CDC317 : CPAR2_600170, Candida tenuis NRRL Y-1498 : CANTEDRAFT_121753 and Debaryomyces hansenii CBS767 : DEHA2E19712g || 1 -1.33 -1.32 -0.99 -1.04 -0.46 0.19 -0.89 -1.46 -0.27 -0.34 -0.78 0.09 -0.03 -0.41 -0.30 -0.05
12644 || orf19.6522 || || || Putative allantoate permease; Gcn4-regulated; Spider biofilm induced || 1 -1.43 -1.42 -0.81 -0.57 -0.46 0.10 -0.83 -0.99 0.06 -0.23 -1.06 -0.13 -0.45 0.11 -0.28 -0.45
12645 || orf19.2906 || PGA41 || || Putative GPI-anchored protein; adhesin-like protein || 1 -1.04 -1.49 -0.76 -0.60 -1.24 0.15 -1.24 -1.30 0.26 -0.45 -1.09 -0.19 -0.14 -0.10 -0.16 -0.40
12646 || orf19.4332 || || || Ortholog of C. dubliniensis CD36 : Cd36_52800, C. parapsilosis CDC317 : CPAR2_303110, Candida tenuis NRRL Y-1498 : CANTEDRAFT_92321 and Debaryomyces hansenii CBS767 : DEHA2G07964g || 1 -0.79 -0.86 -0.70 -0.84 -0.94 -0.08 -0.20 -0.47 0.03 0.01 -0.34 -0.05 -0.37 -0.28 -0.31 0.07
12647 || orf19.304 || || || Putative transporter similar to MDR proteins; fungal-specific; Spider biofilm induced || 1 -0.85 -0.96 -0.92 -0.99 -0.75 -0.01 -0.93 -0.80 -0.66 0.10 -0.47 -0.08 -1.22 -0.81 -0.32 0.00
12648 || orf19.6199 || || || Ortholog(s) have ATP-dependent 5'-3' DNA helicase activity and DNA helicase A complex, alpha DNA polymerase:primase complex, cytosol localization || 1 -0.57 -0.50 -0.63 -1.00 -0.09 -0.22 0.04 -0.24 -0.34 -0.31 -0.35 0.07 -0.87 -0.37 0.05 0.08
12649 || orf19.1272 || || || Protein of unknown function; may play a role in regulation of cell size; rat catheter biofilm repressed || 1 -0.63 -0.64 -1.07 -0.94 -0.52 -0.16 -0.32 -0.40 -0.38 -0.45 -0.18 -0.41 -1.27 -0.37 0.09 0.09
12650 || orf19.971 || SKN7 || || Putative homolog of S. cerevisiae Skn7p, which is predicted to be a response regulator protein in a phosphorelay signal transduction pathway; required for normal hydrogen peroxide resistance || 1 -0.61 -0.55 -0.24 -0.48 -0.41 -0.32 -0.34 -0.24 -0.43 -0.19 -0.43 -0.48 -0.32 -0.24 -0.25 0.03
12651 || orf19.736 || SRB8 || || Putative RNA polymerase II mediator complex subunit; early-stage flow model biofilm induced || 1 -0.81 -0.56 -0.57 -0.49 -0.12 -0.20 -0.38 -0.55 -0.34 -0.58 -0.51 -0.19 -0.35 -0.49 -0.87 -0.16
12652 || orf19.5401 || || || Putative adhesin-like protein; mutation confers hypersensitivity to toxic ergosterol analog; decreased transcription is observed upon fluphenazine treatment; overlaps orf19.5402; merged with orf19.5404 into orf19.5404.1 || 1 -1.04 -0.91 -0.60 -0.67 0.10 -0.51 -0.44 -0.27 -0.05 -0.41 -0.45 -0.53 -0.52 -0.29 -0.61 -0.16
12653 || orf19.292 || || || Ortholog of C. parapsilosis CDC317 : CPAR2_102390, C. dubliniensis CD36 : Cd36_82960, Candida tenuis NRRL Y-1498 : CANTEDRAFT_133198 and Lodderomyces elongisporus NRLL YB-4239 : LELG_02116 || 1 -1.38 -1.26 -1.06 -1.00 -0.30 -0.96 -0.55 -0.20 -0.80 -0.65 -0.68 -1.08 -0.65 -0.51 -1.26 -0.64
12654 || orf19.284 || || || Ortholog of C. dubliniensis CD36 : Cd36_82890, Debaryomyces hansenii CBS767 : DEHA2G01034g, Pichia stipitis Pignal : PICST_32242 and Candida guilliermondii ATCC 6260 : PGUG_04638 || 1 -1.11 -1.24 -0.95 -1.02 -0.47 -0.83 -0.33 -0.22 -0.59 -0.48 -0.80 -1.03 -0.83 -0.54 -1.11 -0.53
12655 || orf19.992 || LKH1 || || Putative leukotriene A(4) hydrolase; repressed during the mating process; Hog1p-induced || 1 -0.73 -0.97 -0.64 -0.96 -0.20 -0.17 -0.22 -0.34 -0.46 -0.63 -0.45 -0.58 -1.24 -0.24 -0.79 -0.45
12656 || orf19.5910 || || || Putative histone acetyltransferase complex subunit; induced upon low-level peroxide stress; Spider biofilm induced || 1 -0.93 -1.04 -1.24 -0.90 -0.01 -0.26 -0.59 -0.40 -0.46 -0.08 -0.47 -0.30 -0.29 -0.56 -0.66 -0.53
12657 || orf19.6860 || || || Ortholog(s) have CDP-diacylglycerol-inositol 3-phosphatidyltransferase activity, role in phosphatidylinositol biosynthetic process and Golgi apparatus, integral to membrane, mitochondrial outer membrane localization || 1 -1.38 -1.37 -1.40 -1.21 -0.70 -0.77 -0.90 -0.93 -0.98 -0.14 -0.60 -0.16 -0.62 -0.97 -0.05 -0.59
12658 || orf19.2307 || || || Ortholog(s) have role in mRNA cleavage, mRNA polyadenylation, mitotic sister chromatid segregation, regulation of G1/S transition of mitotic cell cycle and cytosol, mRNA cleavage and polyadenylation specificity factor complex localization || 1 -0.85 -0.80 -0.98 -0.88 -0.70 -0.64 -0.68 -0.75 -0.61 -0.01 -0.27 -0.21 -0.42 -0.36 -0.70
12659 || orf19.6283 || || || Ortholog(s) have mitochondrion localization || 1 -0.79 -0.69 -0.69 -1.01 -0.50 -0.61 -0.29 -0.36 -0.58 -0.27 -0.34 0.23 -0.19 -0.24 -0.21 -0.50
12660 || orf19.5559 || RAV2 || || Protein similar to S. cerevisiae Rav2; a regulator of (H+)-ATPase in vacuolar membrane; transposon mutation affects filamentous growth || 1 -0.64 -0.60 -0.49 -1.08 -0.51 -0.53 -0.79 -0.74 -0.64 -0.66 -0.00 -0.18 -0.56 -0.66 -0.68 -0.14
12661 || orf19.1563 || ECM3 || || Ortholog(s) have endoplasmic reticulum localization || 1 -1.21 -1.09 -0.52 -0.56 -0.38 -0.14 -0.76 -0.82 0.24 -0.27 -0.53 -0.08 -0.56 -0.64 -0.69 0.24
12662 || orf19.7101 || || || Ortholog(s) have telomeric DNA binding activity, role in protein localization to chromosome, telomere maintenance via telomerase and ASTRA complex, nuclear telomere cap complex localization || 1 -1.52 -1.51 -0.85 -0.56 -0.65 -0.34 -0.86 -0.92 -0.13 -0.20 -0.32 0.22 -1.15 -0.47 -0.51 0.04
12663 || orf19.2105 || || || Putative pre-mRNA-splicing factor; possibly an essential gene, disruptants not obtained by UAU1 method || 1 -1.53 -1.67 -0.80 -0.66 -0.37 -0.10 -0.47 -0.58 0.03 -0.26 -0.38 0.01 -1.15 -0.19 -0.95 0.41
12664 || orf19.5535 || || || Predicted membrane transporter, member of the anion:cation symporter (ACS) family, major facilitator superfamily (MFS) || 1 -1.52 -1.96 -1.05 -1.25 -0.50 0.59 -0.83 -0.64 0.03 -0.41 -0.51 0.09 -1.35 -0.37 -0.51 0.03
12665 || orf19.860 || BMT8 || || Putative beta-mannosyltransferase, member of a 9-gene family including characterized BMT genes with roles in beta-1,2-mannosylation of cell wall phosphopeptidomannan; transposon insertion in promoter region causes decreased colony wrinkling || 1 -1.06 -0.94 -0.80 -0.82 0.01 -0.46 -0.77 -0.60 -0.32 -0.50 -0.18 0.10 -0.99 0.04 -0.41 -0.31
12666 || orf19.1621 || GPA2 || || G-protein alpha subunit; regulates filamentous growth, copper resistance; involved in cAMP-mediated glucose signaling; reports differ on role in cAMP-PKA pathway, MAP kinase cascade; Gpr1 C terminus binds Gpa2; regulates HWP1 and ECE1 || 1 -0.38 -0.49 -0.50 -0.74 -0.13 0.06 -0.80 -0.44 -0.44 -0.28 -0.18 0.25 -0.88 -0.02 -0.14 -0.03
12667 || orf19.7058 || || || Ortholog(s) have role in cellular response to cadmium ion, detoxification of cadmium ion and cytoplasm, nucleus localization || 1 -0.91 -1.11 -1.23 -1.42 0.06 -0.11 -1.01 -0.78 -0.47 -0.59 -0.51 0.15 -0.97 -0.39 -0.46 -0.39
12668 || orf19.2521 || || || Ortholog of C. dubliniensis CD36 : Cd36_26390, Debaryomyces hansenii CBS767 : DEHA2C05302g, Pichia stipitis Pignal : PICST_68531 and Spathaspora passalidarum NRRL Y-27907 : SPAPADRAFT_59916 || 1 -0.93 -1.12 -1.34 -1.28 -0.23 -0.00 -0.73 -0.73 -0.16 -0.12 -0.45 0.02 -1.37 -0.17 -0.47 -0.11
12669 || orf19.1621 || GPA2 || || G-protein alpha subunit; regulates filamentous growth, copper resistance; involved in cAMP-mediated glucose signaling; reports differ on role in cAMP-PKA pathway, MAP kinase cascade; Gpr1 C terminus binds Gpa2; regulates HWP1 and ECE1 || 1 -0.92 -0.89 -1.11 -0.84 0.02 0.12 -0.75 -0.66 -0.47 -0.39 -0.37 0.11 -1.01 -0.24 -0.05 0.15
12670 || orf19.7081 || SPL1 || || Protein similar to S. cerevisiae Spl1p, which is involved in tRNA splicing; member of pyridoxal-phosphate-dependent aminotransferase protein family; predicted to be essential || 1 -0.59 -0.75 -0.87 -0.66 -0.06 -0.17 -0.68 -0.55 -0.42 -0.11 -0.19 0.01 -1.15 -0.33 0.05 -0.04
12671 || orf19.3218 || || || Putative multidrug resistance protein; upregulated by Efg1p || 1 -0.93 -0.87 -1.29 -1.29 0.17 -0.13 -0.81 -0.69 -0.78 -0.53 -0.50 -0.14 -1.87 -1.02 -0.39 0.06
12672 || orf19.301 || PGA18 || || Putative GPI-anchored protein; regulated by Nrg1, Tup1; rat catheter biofilm repressed || 1 -1.20 -0.94 -2.27 -1.47 -0.87 -0.38 -1.26 -1.26 -0.90 -1.00 -0.38 -0.13 -0.72 -0.74 -0.39 0.24
12673 || orf19.301 || PGA18 || || Putative GPI-anchored protein; regulated by Nrg1, Tup1; rat catheter biofilm repressed || 1 -1.76 -1.62 -2.30 -1.54 -0.74 -0.60 -1.53 -1.44 -1.20 -1.04 -0.81 -0.34 -0.71 -1.16 -0.92 -0.09
12674 || orf19.3279 || HYR4 || || Putative GPI-anchored adhesin-like protein; Rim101-repressed; constitutive expression independent of MTL or white-opaque status || 1 -1.43 -1.52 -1.21 -1.51 -0.61 -0.45 -0.57 -0.60 -0.18 -0.82 -1.42 -0.51 -1.06 -0.19 -1.07 -0.44
12675 || orf19.3279 || HYR4 || || Putative GPI-anchored adhesin-like protein; Rim101-repressed; constitutive expression independent of MTL or white-opaque status || 1 -1.34 -1.49 -1.09 -1.42 -0.41 -0.29 -0.50 -0.68 0.02 -0.76 -1.09 -0.48 -1.17 -0.12 -0.84 -0.15
12676 || orf19.309 || DAL5 || || Allantoate permease; nitrogen catabolite repressed, induced in absence of preferred N sources; nitrogen source regulation requires Gat1; possibly essential gene (by UAU1 method); Hap43-repressed || 1 -1.14 -1.26 -0.90 -0.89 -0.74 -0.57 -0.47 -0.50 0.08 -0.78 -0.87 -0.36 -0.84 -0.20 -0.37 0.05
12677 || orf19.6956 || DAL9 || || Putative allantoate permease; fungal-specific (no human or murine homolog) || 1 -1.56 -1.52 -1.00 -0.76 -0.78 -0.46 -0.48 -0.75 -0.01 -0.96 -0.91 -0.69 -0.66 -0.35 -0.35 -0.11
12678 || orf19.1401 || EAP1 || || GPI-anchored cell wall adhesin; Efg1-regulated; mutant suppresses cell adhesion, filamentation, invasive growth defects of S. cerevisiae flo8 or flo11 mutant; biofilm induced; required for biofilm formation; Bcr1-repressed in a/a biofilms || 1 -1.41 -1.68 -0.79 -0.93 -0.55 -0.27 -0.73 -0.75 -0.12 -0.88 -0.69 -0.58 -0.35 -0.49 -0.68 -0.08
12679 || orf19.1401 || EAP1 || || GPI-anchored cell wall adhesin; Efg1-regulated; mutant suppresses cell adhesion, filamentation, invasive growth defects of S. cerevisiae flo8 or flo11 mutant; biofilm induced; required for biofilm formation; Bcr1-repressed in a/a biofilms || 1 -1.91 -2.10 -0.96 -1.21 -0.76 -0.38 -0.83 -1.04 -0.41 -0.87 -0.91 -0.35 -0.85 -0.24 -0.92 -0.01
12680 || orf19.575 || HYR3 || || Putative GPI-anchored adhesin-like protein; similar to Hyr1p induced in high iron; clade-specific repeat variation || 1 -1.00 -1.12 -0.62 -0.90 -0.44 -0.10 -0.59 -0.80 0.16 -0.68 -0.81 -0.28 -0.43 -0.02 -0.34 0.02
12681 || orf19.2495 || GSL1 || || Beta-1,3-glucan synthase subunit; 10 predicted transmembrane regions; caspofungin induced; repressed by yeast-to-hypha transition; young biofilm repressed, induced by biofilm drug exposure; Bcr1-repressed in RPMI a/a biofilms || 1 -1.49 -1.49 -0.87 -0.99 -0.31 0.11 -0.95 -1.11 -0.03 -0.58 -1.32 -0.42 -1.17 -0.46 -0.47 -0.10
12682 || orf19.207 || PGA55 || || GPI-anchored adhesin-like protein; filament induced; regulated by Nrg1, Tup1; regulated upon hyphal formation; mRNA binds to She3 and is localized to yeast-form buds and hyphal tips; induced during chlamydospore formation || 1 -1.35 -1.49 -0.99 -1.68 -0.24 0.02 -0.90 -1.19 -0.54 -0.75 -0.99 -0.73 -0.65 -0.36 -0.55 -0.43
12683 || orf19.1310 || || || Ortholog(s) have role in nucleotide-excision repair and nucleus localization || 1 -1.34 -1.18 -1.31 -1.28 -0.10 -0.28 -0.40 -0.88 -0.68 -0.41 -0.67 -0.51 -0.61 -0.30 -0.39 -0.32
12684 || orf19.1163 || || || Has domain(s) with predicted GTP binding activity || 1 -1.14 -1.49 -0.91 -0.91 -0.49 -0.29 -0.52 -0.41 -0.42 -0.16 -0.37 -0.07 -1.00 -0.35 -0.31 -0.40
12685 || orf19.1217 || || || Ortholog(s) have ribosome binding, ubiquitin-protein ligase activity and role in chromatin modification, chromatin silencing at telomere, protein ubiquitination, ribosome-associated ubiquitin-dependent protein catabolic process || 1 -0.91 -1.16 -1.10 -0.60 -0.51 -0.45 -0.61 -0.49 -0.21 0.07 -0.31 -0.04 -1.10 -0.59 -0.17 -0.38
12686 || orf19.5175 || || || Ortholog(s) have ubiquitin-protein ligase activity, role in ER-associated ubiquitin-dependent protein catabolic process and Doa10p ubiquitin ligase complex, integral to endoplasmic reticulum membrane, nuclear inner membrane localization || 1 -1.10 -1.32 -1.01 -0.73 -1.04 -1.00 -0.69 -0.59 -0.46 -0.09 -0.50 -0.12 -1.02 -0.44 -0.15 -0.35
12687 || orf19.6187 || || || possible pseudouridine monophosphate glycosidase; overlaps orf19.6185 and orf19.618; has intron; Spider biofilm repressed || 1 -1.14 -1.02 -0.95 -1.10 -0.77 -0.72 -0.69 -0.50 -0.74 -0.51 -0.40 -0.53 -0.97 -0.95 -0.66 -0.19
12688 || orf19.1142 || AVT4 || || Putative vacuolar transporter of large neutral amino acids; induced by alpha pheromone in SpiderM medium || 1 -0.95 -0.97 -0.48 -0.84 -0.51 -0.43 -0.71 -0.83 -0.57 -0.66 -0.39 -0.49 -0.49 -0.68 -0.45 -0.12
12689 || orf19.3775 || SSK2 || || MAP kinase kinase kinase (MAPKKK); regulates Hog1 activation and signaling; repressed by ciclopirox olamine || 1 -1.19 -1.27 -0.76 -0.73 -0.80 -0.73 -1.02 -0.77 -0.90 -0.42 -0.40 -0.47 -0.72 -0.42 -0.59 -0.26
12690 || orf19.1341 || PRR2 || || Putative serine/threonine protein kinase; mutation confers resistance to 5-fluorocytosine (5-FC) || 1 -1.70 -1.57 -0.66 -0.70 -1.09 -0.75 -1.17 -0.88 -0.90 -0.87 -0.76 -0.26 -1.21 -0.73 -0.88 -0.38
12691 || orf19.7081 || SPL1 || || Protein similar to S. cerevisiae Spl1p, which is involved in tRNA splicing; member of pyridoxal-phosphate-dependent aminotransferase protein family; predicted to be essential || 1 -1.20 -1.45 -0.72 -1.03 -0.60 -0.49 -0.92 -0.74 -0.59 -0.33 -0.47 -0.49 -1.47 -0.56 -0.60 -0.36
12692 || orf19.4785 || PTC1 || || Putative protein phosphatase of the Type 2C-related family (serine/threonine-specific), similar to S. cerevisiae Ptc1p; mutant shows virulence defect || 1 -0.86 -1.05 -0.86 -0.99 -0.54 -0.46 -0.84 -0.63 -0.52 -0.52 -0.45 -0.19 -0.76 -0.20 -0.28 -0.17
12693 || orf19.3959 || SSD1 || || Protein with role in resistance to host antimicrobial peptides; virulence role in murine infection; functional homolog of S. cerevisiae Ssd1p, which suppresses various mutant phenotypes; constitutively expressed and not cell-cycle regulated || 1 -1.03 -1.07 -1.07 -1.16 -0.60 -0.43 -0.92 -0.82 -0.77 -0.65 -0.82 -0.40 -1.12 -0.49 -0.36 -0.43
12694 || orf19.879 || || || Ortholog(s) have myosin binding activity, role in intracellular mRNA localization, mating type switching and cytoplasm localization || 1 -1.03 -1.15 -1.37 -1.27 -0.47 -0.35 -0.97 -0.91 -0.70 -0.40 -0.64 -0.15 -1.32 -0.63 -0.24 -0.25
12695 || orf19.274 || TFC4 || || Putative RNA polymerase III transcription initiation factor complex (TFIIIC) subunit; induced by Mnl1 under weak acid stress; possibly essential gene, disruptants not obtained by UAU1 method || 1 -1.23 -1.47 -1.05 -1.06 -0.40 -0.17 -0.89 -0.67 -0.45 -0.63 -0.40 0.05 -0.43 -0.28 -0.47 -0.30
12696 || orf19.4221 || ORC4 || || Phosphorylated protein similar to S. cerevisiae Orc4, subunit of the origin recognition complex (ORC); induced by alpha pheromone in SpiderM medium || 1 -0.96 -1.16 -0.81 -1.38 -0.34 -0.48 -0.56 -0.79 -0.44 -0.61 -0.38 -0.04 -0.47 -0.50 -0.39 -0.16
12697 || orf19.1166 || CTA3 || || Protein similar to S. cerevisiae Ede1p, which is involved in endocytosis; activates transcription in 1-hybrid assay in S. cerevisiae || 1 -1.01 -1.11 -0.69 -0.80 -0.48 -0.54 -0.61 -0.66 -0.45 -0.73 -0.61 -0.36 -0.55 -0.36 -0.33 -0.43
12698 || orf19.1166 || CTA3 || || Protein similar to S. cerevisiae Ede1p, which is involved in endocytosis; activates transcription in 1-hybrid assay in S. cerevisiae || 1 -0.72 -0.89 -0.50 -0.58 -0.23 -0.31 -0.63 -0.65 -0.23 -0.57 -0.61 -0.14 -0.26 -0.16 -0.05 -0.28
12699 || orf19.1142 || AVT4 || || Putative vacuolar transporter of large neutral amino acids; induced by alpha pheromone in SpiderM medium || 1 -0.84 -0.96 -0.40 -0.63 -0.47 -0.09 -0.71 -0.66 -0.53 -0.86 -0.77 -0.33 -0.71 -0.42 -0.37 0.30
12700 || orf19.206 || || || Putative adhesin-like protein || 1 -0.80 -0.89 -0.38 -0.40 -0.36 -0.13 -0.49 -0.37 -0.50 -0.74 -0.58 -0.24 -0.56 0.04 -0.25 -0.04
12701 || orf19.7359 || CRZ1 || || Calcineurin-regulated C2H2 transcription factor; role in maintenance of membrane integrity, azole tolerance; not required for mouse virulence; repressed by low iron; regulates Ca++ influx during alkaline pH response; Spider biofilm induced || 1 -1.87 -1.73 -0.92 -0.86 -0.66 -0.23 -1.01 -1.70 -0.99 -0.93 -1.10 -0.15 -0.76 0.01 -0.60 0.05
12702 || orf19.301 || PGA18 || || Putative GPI-anchored protein; regulated by Nrg1, Tup1; rat catheter biofilm repressed || 1 -1.68 -1.77 -1.08 -1.11 0.01 0.04 -1.34 -1.29 -0.88 -0.89 -0.17 0.34 -0.66 -0.29 -0.20 0.15
12703 || orf19.5148 || CYR1 || || Class III adenylyl cyclase; mutant lacks cAMP; mutant hyphal growth defect rescued by exogenous cAMP; required for mouse mucosal or systemic infection; role in macrophage sensitivity, apoptosis; downstream of Ras1p and CO2 signaling || 1 -1.23 -1.02 -0.81 -0.70 -0.08 0.15 -0.81 -1.03 -0.40 -0.89 -0.55 0.04 -0.79 0.10 -0.26 -0.00
12704 || orf19.7114 || CSA1 || || Surface antigen on elongating hyphae and buds; strain variation in repeat number; ciclopirox, filament induced, alkaline induced by Rim101; Efg1-, Cph1, Hap43-regulated; required for WT RPMI biofilm formation; Bcr1-induced in a/a biofilms || 1 -1.83 -2.08 -0.95 -1.29 -0.42 0.06 -1.93 -1.35 -0.69 -1.41 -0.88 -0.21 -0.96 -0.44 -0.99 -0.04
12705 || orf19.7114 || CSA1 || || Surface antigen on elongating hyphae and buds; strain variation in repeat number; ciclopirox, filament induced, alkaline induced by Rim101; Efg1-, Cph1, Hap43-regulated; required for WT RPMI biofilm formation; Bcr1-induced in a/a biofilms || 1 -1.19 -1.56 -1.05 -1.26 -0.22 -0.11 -1.36 -1.13 -0.92 -1.22 -0.53 -0.26 -0.78 -0.35 -0.49 0.36
12706 || orf19.7114 || CSA1 || || Surface antigen on elongating hyphae and buds; strain variation in repeat number; ciclopirox, filament induced, alkaline induced by Rim101; Efg1-, Cph1, Hap43-regulated; required for WT RPMI biofilm formation; Bcr1-induced in a/a biofilms || 1 -1.63 -1.65 -1.33 -1.67 0.02 0.04 -1.63 -1.39 -1.08 -1.50 -0.74 -0.74 -0.76 -0.46 -0.64 0.41
12707 || orf19.374 || || || Ortholog(s) have role in protein targeting to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway || 1 -0.53 -0.55 -0.30 -0.29 0.10 0.03 -0.33 -0.42 -0.20 -0.36 -0.31 -0.16 -0.63 -0.29 0.12 0.25
12708 || orf19.5821 || || || Ortholog of S. cerevisiae : YML002W, C. glabrata CBS138 : CAGL0L07634g, C. dubliniensis CD36 : Cd36_17530, C. parapsilosis CDC317 : CPAR2_212430 and Candida tenuis NRRL Y-1498 : CANTEDRAFT_128807 || 1 -0.68 -0.63 -0.57 -0.76 0.10 -0.07 -0.59 -0.82 -0.26 -0.60 -0.32 0.06 -0.85 -0.56 0.01 0.35
12709 || orf19.6134 || || || Ortholog(s) have role in ER-dependent peroxisome organization, retrograde vesicle-mediated transport, Golgi to ER and Dsl1p complex, endoplasmic reticulum membrane, nuclear envelope, peroxisome localization || 1 -0.78 -0.74 -0.79 -1.17 -0.22 -0.31 -0.68 -0.63 -0.56 -0.34 -0.07 -0.13 -0.88 -0.37 0.21 0.33
12710 || orf19.5776 || TOM1 || || Putative E3 ubiquitin ligase; transcript regulated by Nrg1 and Mig1 || 1 -0.76 -0.77 -0.71 -0.69 -0.33 -0.20 -0.60 -0.51 -0.46 -0.51 -0.31 -0.06 -0.93 -0.34 0.12 0.22
12711 || orf19.7497 || || || Ortholog(s) have ubiquitin-protein ligase activity, role in protein ubiquitination involved in ubiquitin-dependent protein catabolic process and Cul3-RING ubiquitin ligase complex, cytoplasm, nucleus localization || 1 -0.74 -0.87 -0.66 -0.75 -0.27 -0.24 -0.46 -0.62 -0.23 -0.40 -0.24 0.10 -0.70 -0.38 0.18 0.26
12712 || orf19.7497 || || || Ortholog(s) have ubiquitin-protein ligase activity, role in protein ubiquitination involved in ubiquitin-dependent protein catabolic process and Cul3-RING ubiquitin ligase complex, cytoplasm, nucleus localization || 1 -0.72 -0.74 -0.61 -0.48 -0.20 -0.32 -0.28 -0.51 -0.37 -0.34 -0.28 -0.02 -0.51 -0.34 0.09 0.16
12713 || orf19.4432 || KSP1 || || Putative serine/threonine protein kinase; mRNA binds She3 and is localized to hyphal tips; mutation confers hypersensitivity to amphotericin B || 1 -0.67 -0.88 -0.54 -0.85 -0.28 -0.32 -0.28 -0.75 -0.57 -0.71 -0.63 -0.11 -0.69 -0.64 0.01 0.36
12714 || orf19.4432 || KSP1 || || Putative serine/threonine protein kinase; mRNA binds She3 and is localized to hyphal tips; mutation confers hypersensitivity to amphotericin B || 1 -0.59 -0.58 -0.58 -0.75 -0.18 -0.17 -0.28 -0.74 -0.18 -0.67 -0.49 0.05 -0.41 -0.39 0.00 0.38
12715 || orf19.478 || || || Protein required for fusion of cvt-vesicles and autophagosomes with the vacuole; plays a role in autophagy, protein targeting to vacuole and vesicle docking; flow model biofilm induced || 1 -0.98 -1.09 -0.53 -0.76 -0.37 -0.08 -0.22 -0.73 -0.40 -0.63 -0.15 -0.02 -0.38 -0.50 0.11 0.18
12716 || orf19.7242 || NCR1 || || Putative vacuolar membrane protein; predicted role in sphingolipid metabolism; transcript regulated by Nrg1 and Mig1; induced by prostaglandins || 1 -1.74 -1.78 -1.29 -1.28 -0.74 -0.62 -0.51 -0.74 -0.28 -0.75 -0.66 -0.00 -0.86 -0.75 0.51 0.00
12717 || orf19.6889 || MKK2 || || Ortholog of S. cerevisiae Mkk2; MAP kinase kinase involved in signal transduction; macrophage-downregulated; mutants are viable and hypersensitive to caspofungin || 1 -0.41 -0.51 -0.72 -0.72 -0.37 -0.15 -0.20 -0.50 -0.23 -0.48 -0.51 -0.40 -0.58 -0.41 -0.33 -0.10
12718 || orf19.5318 || RAD1 || || Putative single-stranded DNA endonuclease; transcript regulated by Nrg1; macrophage-induced gene || 1 -0.48 -0.46 -0.46 -0.81 -0.44 -0.27 -0.30 -0.56 -0.06 -0.49 -0.27 0.00 -0.26 -0.28 -0.43 0.29
12719 || orf19.4524 || ZCF24 || || Predicted Zn(II)2Cys6 transcription factor; caspofungin induced; Hap43-repressed || 1 -0.55 -0.60 -1.15 -1.08 -0.85 -0.77 -0.37 -0.74 -0.36 -1.02 -0.52 -0.24 -0.36 -0.30 -0.31 0.42
12720 || orf19.7579 || FGR34 || || Protein lacking an ortholog in S. cerevisiae; transposon mutation affects filamentous growth || 1 -0.64 -0.72 -0.58 -0.53 -0.86 -0.61 -0.42 -0.39 -0.41 -0.57 -0.63 -0.44 -0.76 -0.21 -0.71 -0.14
12721 || orf19.6923 || || || Ortholog(s) have chromatin binding activity, role in RNA polymerase II transcriptional preinitiation complex assembly and transcription factor TFIID complex localization || 1 -0.60 -0.74 -0.54 -0.64 -0.62 -0.52 -0.29 -0.30 -0.23 -0.40 -0.37 -0.29 -0.74 -0.33 -0.66 -0.04
12722 || orf19.3308 || STB5 || || Putative transcription factor with zinc cluster DNA-binding motif; has similarity to S. cerevisiae Stb5p; Hap43p-repressed gene || 1 -0.74 -0.76 -0.68 -0.72 -0.72 -0.85 -0.55 -0.68 -0.40 -1.10 -0.27 -0.46 -1.05 -0.31 -0.56 0.21
12723 || orf19.4595 || || || Ortholog of C. dubliniensis CD36 : Cd36_41860, C. parapsilosis CDC317 : CPAR2_400440, Candida tenuis NRRL Y-1498 : CANTEDRAFT_103033 and Debaryomyces hansenii CBS767 : DEHA2B03234g || 1 -0.94 -0.89 -0.90 -1.13 -0.90 -0.74 -0.83 -0.94 -0.86 -1.11 -0.33 -0.44 -0.89 -0.49 -0.99 0.27
12724 || orf19.4131 || || || Ortholog(s) have role in protein folding in endoplasmic reticulum and ER membrane protein complex localization || 1 -0.39 -0.59 -0.61 -0.65 -0.52 -0.82 -0.41 -0.61 -0.62 -0.60 -0.37 -0.31 -0.54 -0.36 -0.41 -0.18
12725 || orf19.7001 || YCK2 || || Plasma membrane protein similar to S. cerevisiae casein kinase I, Yck2p; null mutant has defect in damaging oral epithelial cells and in hyphal branching; transcription is activated in weak acid stress or on contact with host cells || 1 -0.91 -1.04 -1.25 -1.18 -0.68 -0.91 -0.41 -0.72 -1.10 -0.78 -0.44 -0.51 -0.85 -0.32 -0.20 -0.23
12726 || orf19.5852 || || || Protein of unknown function; rat catheter biofilm repressed || 1 -1.08 -1.02 -1.24 -0.55 -0.82 -1.19 -0.35 -0.65 -0.60 -0.67 -0.49 -0.11 -0.69 -0.43 -0.61 0.15
12727 || orf19.111 || CAN2 || || Basic amino acid permease; arginine metabolism; regulated by Nrg1/Tup1; caspofungin, flucytosine induced; colony morphology-related regulation by Ssn6; Hap43-repressed; rat catheter and Spider biofilm induced; promoter bound by Efg1 || 1 -1.67 -1.36 -2.81 -2.15 -2.54 -2.68 -0.15 -0.88 -0.86 -1.37 0.37 0.34 -2.02 -1.18 -1.73 0.79
12728 || orf19.393 || APS3 || || Component of the adaptor complex AP-3, which is involved in vacuolar protein sorting || 1 -0.62 -0.82 -0.91 -0.71 -1.25 -1.08 -0.24 -0.28 -0.42 -0.62 -0.08 -0.15 -0.91 -0.38 -0.23 0.30
12729 || orf19.505 || SRV2 || || Adenylate cyclase-associated protein; regulates adenylate cyclase activity; required for wild-type germ tube formation and for virulence in mice; mutant defects in filamentous growth are rescued by cAMP or dbcAMP; Spider biofilm repressed || 1 -0.91 -0.98 -1.22 -1.24 -0.76 -0.75 -0.26 -0.48 -0.56 -0.51 -0.23 -0.18 -1.02 -0.38 -0.43 -0.05
12730 || orf19.6729 || TIP120 || || Protein similar to human CAND1 (Cullin-Associated Nedd8-Dissociated) protein involved in regulation of SCF complexes; binds unnedddylated cullin Cdc53; mutants are viable || 1 -0.69 -0.77 -0.85 -1.10 -0.75 -0.65 -0.16 -0.47 -0.27 -0.61 -0.22 -0.08 -0.81 -0.05 -0.38 0.15
12731 || orf19.4395 || || || Putative actin cytoskeleton component; protein present in exponential and stationary growth phase yeast cultures || 1 -0.63 -0.92 -0.95 -0.78 -0.95 -0.87 -0.08 -0.16 -0.27 -0.43 -0.27 -0.13 -0.71 -0.09 -0.60 0.09
12732 || orf19.3058 || COQ6 || || Ortholog(s) have role in ubiquinone biosynthetic process and mitochondrial inner membrane localization || 1 -0.62 -0.68 -0.94 -1.20 -0.65 -1.00 -0.18 -0.12 -0.35 -0.58 -0.30 -0.14 -0.97 -0.20 -0.92 -0.16
12733 || orf19.4950 || AKR1 || || Ankyrin-repeat protein; induced by fluphenazine || 1 -0.98 -0.94 -1.38 -1.18 -0.82 -0.94 -0.11 -0.67 -0.81 -0.68 -0.19 -0.18 -0.53 -0.01 -0.22 0.24
12734 || orf19.1190 || STV1 || || Predicted subunit a of vacuolar proton-translocating ATPase V0 domain, Golgi isoform || 1 -1.05 -1.12 -1.18 -1.29 -0.25 -0.55 -0.73 -0.60 -0.47 -0.73 -0.03 -0.16 -0.93 -0.34 -0.45 0.26
12735 || orf19.860 || BMT8 || || Putative beta-mannosyltransferase, member of a 9-gene family including characterized BMT genes with roles in beta-1,2-mannosylation of cell wall phosphopeptidomannan; transposon insertion in promoter region causes decreased colony wrinkling || 1 -0.77 -0.96 -0.96 -1.07 -0.20 -0.56 -0.44 -0.38 -0.41 -0.78 -0.20 0.19 -1.04 -0.49 -0.55 0.03
12736 || orf19.3822 || SCS7 || || Putative ceramide hydroxylase; regulated by Nrg1; induced in high iron; fluconazole-induced; Hap43-repressed; Spider biofilm induced || 1 -1.00 -1.10 -1.01 -1.28 -0.78 -0.64 -0.12 -0.29 -0.18 -0.68 -0.14 -0.18 -0.79 -0.71 -0.79 0.45
12737 || orf19.2069 || SMF3 || || Putative vacuolar iron transporter; alkaline upregulated; caspofungin repressed; induced by Mnl1 under weak acid stress; Hap43-repressed || 1 -1.47 -1.25 -1.50 -1.29 -1.19 -0.88 -0.36 -0.33 -0.86 -1.10 0.16 -0.45 -0.56 -0.59 -1.07 0.54
12738 || orf19.5674 || PGA10 || || GPI anchored membrane protein; utilization of hemin and hemoglobin for Fe in host; Rim101 at ph8/hypoxia/ketoconazole/ciclopirox/hypha-induced; required for RPMI biofilm formation, Bcr1-induced in a/a biofilm; rat catheter biofilm repressed || 1 -2.21 -3.29 -3.40 -3.50 -2.24 -1.58 -1.10 -1.40 -1.39 -3.21 1.13 -0.05 -1.92 -1.74 -1.98 1.14
12739 || orf19.5674 || PGA10 || || GPI anchored membrane protein; utilization of hemin and hemoglobin for Fe in host; Rim101 at ph8/hypoxia/ketoconazole/ciclopirox/hypha-induced; required for RPMI biofilm formation, Bcr1-induced in a/a biofilm; rat catheter biofilm repressed || 1 -3.08 -2.94 -3.11 -3.92 -1.60 -1.65 -1.29 -2.01 -2.30 -2.31 1.01 0.06 -2.51 -2.69 -2.18 1.16
12740 || orf19.4233 || THR4 || || Putative threonine synthase; protein present in exponential and stationary growth phase yeast cultures; Gcn4p-regulated; sumoylation target || 1 -1.68 -1.87 -2.17 -2.00 -0.70 -0.48 -0.38 -0.56 -0.89 -1.29 0.84 0.48 -1.44 -1.28 -0.29 0.71
12741 || orf19.953.1 || COF1 || || Putative cofilin; macrophage-induced protein; protein present in exponential and stationary-phase yeast cells, but higher amounts in stationary phase || 1 -0.89 -0.96 -0.76 -0.62 -0.63 -0.35 -0.28 -0.30 -0.34 -0.77 0.29 0.44 -0.65 -0.67 -0.20 0.20
12742 || orf19.953.1 || COF1 || || Putative cofilin; macrophage-induced protein; protein present in exponential and stationary-phase yeast cells, but higher amounts in stationary phase || 1 -0.56 -0.63 -0.41 -0.63 -0.68 -0.46 -0.37 -0.50 -0.41 -0.59 0.07 0.07 -0.50 -0.74 -0.47 0.23
12743 || orf19.7213 || || || Putative ATP-dependent RNA helicase; fungal-specific (no human or murine homolog) || 1 -1.00 -1.04 -0.83 -0.82 -0.68 -0.62 -0.71 -0.87 -0.64 -0.71 -0.07 0.23 -0.94 -0.25 -0.50 0.09
12744 || orf19.7213 || || || Putative ATP-dependent RNA helicase; fungal-specific (no human or murine homolog) || 1 -1.15 -1.15 -1.13 -1.02 -0.76 -0.71 -0.77 -1.15 -0.69 -0.71 -0.22 0.14 -0.94 -0.28 -0.49 0.18
12745 || orf19.2485 || || || Ortholog(s) have structural constituent of nuclear pore activity and role in chromosome segregation, mitotic spindle assembly checkpoint, nuclear pore complex assembly, protein targeting to nuclear inner membrane || 1 -0.89 -1.00 -1.17 -0.97 -0.74 -0.69 -0.93 -0.62 -0.66 -0.35 -0.12 0.20 -0.83 0.17 -0.74 0.24
12746 || orf19.4106 || || || Ortholog of S. cerevisiae : YJR141W, C. glabrata CBS138 : CAGL0M00264g, C. dubliniensis CD36 : Cd36_20520, C. parapsilosis CDC317 : CPAR2_104880 and Candida tenuis NRRL Y-1498 : CANTEDRAFT_126860 || 1 -0.99 -1.09 -1.05 -0.99 -0.83 -0.48 -0.57 -0.90 -0.58 0.11 -0.29 0.07 -1.14 -0.39 -0.70 0.42
12747 || orf19.2194 || || || Phosphorylated protein of unknown function || 1 -1.07 -1.02 -1.02 -0.67 -0.60 -0.32 -0.45 -0.61 -0.26 -0.05 0.10 0.24 -0.89 -0.34 -0.28 0.44
12748 || orf19.5463 || SEC6 || || Predicted subunit of the exocyst complex, involved in exocytosis; localizes to a crescent on the surface of the hyphal tip; Hap43p-repressed gene, overlaps orf19.5464 and orf19.5465 || 1 -0.76 -0.73 -0.41 -0.51 -0.62 -0.34 -0.36 -0.28 -0.03 -0.35 0.08 -0.04 -0.58 -0.30 -0.28 -0.02
12749 || orf19.1290 || XKS1 || || Putative xylulokinase; Hap43-repressed; induced by prostaglandins; rat catheter biofilm repressed || 1 -1.46 -1.27 -1.19 -1.43 -0.84 -0.10 -0.22 -0.62 -0.05 -1.32 -0.47 -0.21 -1.32 -0.92 -0.64 -0.09
12750 || orf19.3720 || || || Ortholog(s) have endo-1,4-beta-xylanase activity and SCF ubiquitin ligase complex, cytoplasm localization || 1 -1.30 -1.43 -0.53 -1.00 -0.92 -0.13 -0.03 -0.62 0.08 -1.19 -0.25 0.60 -0.90 -0.90 -0.54 0.02
12751 || orf19.6263 || || || Predicted MFS membrane transporter; member of the monocarboxylate porter (MCP) family; Spider biofilm induced || 1 -1.48 -1.46 -0.96 -1.36 -0.81 -0.14 0.19 -0.13 0.37 -0.75 -0.59 0.10 -0.70 0.15 -0.23 0.03
12752 || orf19.309 || DAL5 || || Allantoate permease; nitrogen catabolite repressed, induced in absence of preferred N sources; nitrogen source regulation requires Gat1; possibly essential gene (by UAU1 method); Hap43-repressed || 1 -1.80 -2.15 -1.18 -0.96 -0.77 -0.58 -0.35 -0.54 0.22 -0.82 -0.64 -0.21 -0.65 0.20 -0.29 0.18
12753 || orf19.6956 || DAL9 || || Putative allantoate permease; fungal-specific (no human or murine homolog) || 1 -1.79 -2.21 -1.24 -0.95 -1.03 -0.74 -0.39 -0.62 0.29 -0.78 -0.71 -0.19 -0.81 -0.03 -0.36 0.31
12754 || orf19.575 || HYR3 || || Putative GPI-anchored adhesin-like protein; similar to Hyr1p induced in high iron; clade-specific repeat variation || 1 -1.58 -1.39 -0.66 -0.73 -0.58 -0.18 -0.09 -0.43 -0.02 -0.69 -0.57 0.11 -0.48 -0.37 -0.42 0.23
12755 || orf19.1457 || || || Putative RNA polymerase transcription factor TFIIH core component; possibly an essential gene, disruptants not obtained by UAU1 method || 1 -1.54 -1.14 -0.91 -0.70 -0.54 -0.35 -0.35 -0.41 0.08 -0.38 -0.10 -0.00 -0.56 -0.38 -0.35 -0.01
12756 || orf19.4213 || FET31 || || Putative iron transport multicopper oxidase precursor; flucytosine induced; caspofungin repressed || 1 -1.42 -1.44 -1.21 -0.69 -0.46 -0.73 -0.71 -0.27 0.11 -0.36 -0.59 -0.05 -0.80 0.28 -0.89 -0.01
12757 || orf19.4213 || FET31 || || Putative iron transport multicopper oxidase precursor; flucytosine induced; caspofungin repressed || 1 -1.27 -1.56 -0.65 -0.45 -0.48 -0.84 -0.32 -0.39 0.14 -0.46 -0.62 -0.41 -0.88 0.01 -0.70 -0.60
12758 || orf19.7156 || FAA2-3 || || Predicted acyl CoA synthetase || 1 -0.95 -1.00 -0.82 -0.41 -0.23 -0.41 -0.11 -0.08 0.02 -0.41 -0.58 0.12 -0.85 -0.28 -0.56 0.21
12759 || orf19.4549 || FGR38 || || Protein lacking an ortholog in S. cerevisiae; member of a family of related proteins; transposon mutation affects filamentous growth; macrophage-induced gene; Hap43p-repressed gene || 1 -1.00 -1.04 -0.32 -0.28 -0.95 -0.49 -0.17 -0.34 0.10 -0.15 -0.55 0.12 -0.69 0.08 -0.45 0.03
12760 || orf19.5422 || || || Ortholog of C. dubliniensis CD36 : Cd36_80400, Candida tropicalis MYA-3404 : CTRG_06188 and Candida albicans WO-1 : CAWG_02379 || 1 -1.44 -1.59 -1.78 -0.32 -0.82 -0.80 -0.64 -0.55 0.04 -0.58 -0.19 0.25 -0.80 -0.65 -0.68 -0.00
12761 || orf19.6287 || AAT21 || || Putative aspartate aminotransferase; stationary phase enriched protein; Gcn4-regulated; Spider biofilm induced || 1 -1.84 -2.00 -1.43 -1.12 -1.24 -0.88 -0.72 -0.81 -0.78 -0.56 -0.63 -0.27 -0.96 -0.06 0.17 -0.41
12762 || orf19.6287 || AAT21 || || Putative aspartate aminotransferase; stationary phase enriched protein; Gcn4-regulated; Spider biofilm induced || 1 -1.41 -1.39 -0.82 -0.72 -0.77 -0.43 -0.67 -0.62 -0.37 -0.31 -0.52 0.22 -0.72 0.33 0.41 -0.23
12763 || orf19.816 || DCK2 || || Protein similar to S. cerevisiae Ylr422wp; transposon mutation affects filamentous growth; induced by Mnl1p under weak acid stress || 1 -0.73 -0.77 -0.59 -0.82 -0.22 -0.39 -0.18 -0.28 0.00 -0.62 -0.40 0.07 -0.48 0.10 0.07 0.17
12764 || orf19.5552 || || || Putative transcriptional regulator of ribonucleotide reductase genes; Spider biofilm induced || 1 -1.41 -1.67 -0.94 -1.54 -0.03 -0.47 -0.46 -0.76 -0.01 -1.10 -0.63 -0.05 -0.09 0.04 -0.09 0.47
12765 || orf19.5890 || || || Ortholog of C. dubliniensis CD36 : Cd36_84350, C. parapsilosis CDC317 : CPAR2_806070, Candida tenuis NRRL Y-1498 : CANTEDRAFT_133308 and Debaryomyces hansenii CBS767 : DEHA2F11682g || 1 -1.23 -1.49 -1.57 -2.02 -0.22 -0.02 -0.26 -0.50 -0.08 -1.03 -0.54 -0.49 -0.20 -0.17 -0.10 0.14
12766 || orf19.3279 || HYR4 || || Putative GPI-anchored adhesin-like protein; Rim101-repressed; constitutive expression independent of MTL or white-opaque status || 1 -1.32 -1.29 -0.93 -1.53 0.03 0.17 -0.38 -0.63 -0.02 -0.94 -0.60 -0.08 -0.69 -0.01 -0.68 -0.02
12767 || orf19.2972 || PDE2 || || High affinity cyclic nucleotide phosphodiesterase; moderates signaling by cAMP; required for virulence, switching, cell wall, hyphal, not pseudohyphal growth; expressed shortly after hyphal induction; rat catheter and Spider biofilm induced || 1 -1.56 -1.72 -1.42 -1.80 -0.47 -0.13 0.10 -1.70 -0.72 -1.50 -0.51 -0.29 -0.04 -0.13 -0.48 0.20
12768 || orf19.7437 || || || Putative protein of unknown function; Hap43p-repressed gene; ortholog of S. cerevisiae YJL218W || 1 -1.87 -1.73 -1.59 -1.78 -0.79 -0.46 0.24 -0.29 -0.26 -1.60 -0.49 -0.95 -0.19 -0.31 -0.67 -0.12
12769 || orf19.7612 || CTM1 || || Putative cytochrome c lysine methyltransferase; regulated by Gcn2 and Gcn4; transcript induced by Mnl1 under weak acid stress; early-stage flow model biofilm induced || 1 -0.62 -0.60 -0.57 -1.05 -0.56 -0.20 0.01 -0.17 0.03 -0.77 -0.11 -0.18 0.08 -0.16 -0.32 0.26
12770 || orf19.575 || HYR3 || || Putative GPI-anchored adhesin-like protein; similar to Hyr1p induced in high iron; clade-specific repeat variation || 1 -0.73 -0.79 -1.31 -1.14 -0.80 -0.23 -0.54 -0.89 -0.08 -0.84 -1.04 -0.24 -0.20 -0.00 -0.63 0.03
12771 || orf19.3308 || STB5 || || Putative transcription factor with zinc cluster DNA-binding motif; has similarity to S. cerevisiae Stb5p; Hap43p-repressed gene || 1 -0.49 -0.69 -0.62 -1.18 -0.52 -1.03 -0.51 -0.80 -0.44 -1.09 -0.40 -0.54 -0.80 -0.45 -0.21 0.04
12772 || orf19.3819 || || || Protein of unknown function; transcript detected on high-resolution tiling arrays || 1 -0.26 -0.66 -0.24 -0.88 -0.01 -0.29 -0.49 -0.34 -0.29 -0.93 -0.48 -0.49 -0.47 -0.23 -0.38 -0.34
12773 || orf19.2129 || || || Ortholog of S. cerevisiae Spo71; a meiosis-specific protein required for spore wall formation during sporulation in S. cerevisiae; possibly an essential gene, disruptants not obtained by UAU1 method || 1 -0.64 -0.75 -0.51 -0.83 -0.24 -0.47 0.13 -0.26 0.51 -0.21 -0.31 -0.18 -0.30 -0.32 -0.34 -0.29
12774 || orf19.3469 || || || S. cerevisiae ortholog Stb1 has a role in regulation of MBF-specific transcription at Start; induced in a cyr1 null mutant; Spider biofilm induced || 1 -1.10 -1.18 -0.79 -0.84 -0.37 -0.55 0.12 -0.29 -0.24 -0.05 -0.57 0.09 -0.28 -0.65 -1.21 -0.37
12775 || orf19.5179 || LIP5 || || Cold-activated secreted lipase, differentially expressed lipase gene family member with possible roles in nutrition and acidic microenvironment; LIP5 and LIP8 expressed at all stages of mucosal and systemic infection; affects filamentation || 1 -1.07 -1.20 -0.20 -0.95 -0.95 -0.88 -0.38 -0.66 0.07 0.50 -0.43 -0.14 -0.51 -0.48 -1.20 -1.01
12776 || orf19.438 || || || Ortholog of S. cerevisiae : YHR078W, C. glabrata CBS138 : CAGL0J10626g, C. dubliniensis CD36 : Cd36_05020, Candida tenuis NRRL Y-1498 : CANTEDRAFT_95811 and Debaryomyces hansenii CBS767 : DEHA2E07524g || 1 -0.82 -0.96 -0.48 -0.54 -0.60 -0.45 -0.34 -0.22 0.69 0.21 0.01 -0.08 -0.10 -0.05 -0.52 -0.03
12777 || orf19.7613 || HCR1 || || Putative translation initiation factor; repressed upon phagocytosis by murine macrophage; Spider biofilm repressed || 1 -0.66 -0.67 -0.34 -0.53 -0.19 -0.43 -0.39 -0.22 0.05 0.30 -0.10 0.03 -0.30 0.04 -0.35 -0.06
12778 || orf19.1283 || MEC1 || || Cell cycle checkpoint protein with a role in genome integrity; RNA abundance regulated by tyrosol and cell density || 1 -0.78 -1.03 -0.32 -0.39 -0.36 -0.68 -0.39 -0.37 0.29 0.04 -0.26 -0.40 -0.18 0.60 -0.76 -0.32
12779 || orf19.2678 || BUB1 || || Putative cell cycle checkpoint kinase; mutation confers increased sensitivity to nocodazole || 1 -0.42 -0.75 -0.04 -0.25 -0.60 -0.96 -0.40 -0.11 0.03 -0.08 -0.04 -0.32 -0.09 -0.16 -1.03 -0.27
12780 || orf19.6984 || || || Ortholog of C. dubliniensis CD36 : Cd36_85460, C. parapsilosis CDC317 : CPAR2_405760, Candida tenuis NRRL Y-1498 : CANTEDRAFT_116052 and Debaryomyces hansenii CBS767 : DEHA2D16940g || 1 -1.11 -1.11 -0.83 -0.47 -1.18 -0.97 -0.22 -0.35 -0.09 0.55 -0.60 -0.32 0.17 -0.41 -0.26 -0.27
12781 || orf19.3228 || || || Putative endosomal transmembrane protein; Hap43p-induced; mutation confers hypersensitivity to amphotericin B || 1 -0.74 -0.87 -0.36 -0.05 -0.59 -0.57 -0.27 -0.14 0.15 0.12 -0.34 -0.22 -0.17 -0.49 -0.31 -0.18
12782 || orf19.1659 || ALG8 || || Putative glucosyltransferase involved in cell wall mannan biosynthesis; transcription is elevated in nik1 and sln1 homozygous null mutants, but not in the chk1 null mutant; possibly an essential gene, disruptants not obtained by UAU1 method || 1 -0.69 -0.63 -0.19 0.17 -0.86 -0.67 -0.26 0.19 -0.12 0.14 -0.23 -0.03 -0.12 -0.33 -0.29 -0.28
12783 || orf19.3061 || IMP1 || || Predicted subunit of the mitochondrial inner membrane peptidase complex involved in protein targeting to mitochondria || 1 -0.35 -0.36 -0.23 -0.27 -0.57 -0.76 -0.19 0.29 -0.19 -0.33 0.11 -0.29 -0.72 -0.52 -0.59 0.04
12784 || orf19.2965 || || || Putative guanyl-nucleotide exchange factor; Spider biofilm repressed || 1 -0.31 -0.65 -0.20 -0.52 -0.66 -0.71 0.08 0.13 -0.20 -0.12 0.13 -0.26 -0.69 -0.05 -0.72 0.03
12785 || orf19.5825.1 || || || Ortholog(s) have role in ER to Golgi vesicle-mediated transport and ER to Golgi transport vesicle, endoplasmic reticulum membrane, integral to Golgi membrane localization || 1 -0.37 -0.20 -0.49 -0.65 -0.38 -0.79 -0.09 0.20 -0.45 -0.36 -0.01 -0.14 -0.35 -0.04 -0.42 0.10
12786 || orf19.2909 || ERG26 || || C-3 sterol dehydrogenase, catalyzes the 2nd of 3 steps required to remove 2 C-4 methyl groups from an intermediate in ergosterol biosynthesis; amphotericin B, caspofungin repressed; Spider biofilm repressed || 1 -0.18 -0.37 -0.78 -0.70 -1.14 -0.94 -0.01 0.12 -0.06 -0.16 0.00 -0.22 -0.42 0.37 -0.79 0.25
12787 || orf19.3356 || ESP1 || || Putative caspase-like cysteine protease; mutation confers increased sensitivity to nocodazole; periodic mRNA expression, peak at cell-cycle S/G2 phase; mRNA binds She3 || 1 -0.31 -0.23 -0.87 -0.57 -0.87 -1.25 -0.05 -0.11 -0.65 -0.22 -0.10 -0.15 -0.26 0.28 -0.95 0.24
12788 || orf19.645.1 || VMA13 || || Predicted proton-transporting ATPase; predicted role in ATP hydrolysis coupled proton transport; rat catheter biofilm repressed || 1 -0.31 -0.31 -0.76 -0.43 -1.12 -1.13 -0.05 -0.31 -0.32 -0.47 -0.30 -0.34 -0.16 0.16 -0.40 0.09
12789 || orf19.6462 || || || Ortholog(s) have role in protein folding in endoplasmic reticulum and ER membrane protein complex, cytosol localization || 1 -0.53 -0.63 -0.62 -0.66 -1.13 -1.06 -0.40 -0.68 -0.29 -0.34 -0.51 -0.34 0.33 -0.28 -0.37 -0.10
12790 || orf19.1685 || ZCF7 || || Predicted Zn(II)2Cys6 transcription factor; mutant shows reduced colony wrinkling on Spider medium and is unable to utilize mannitol as a carbon source; mutants have increased colonization of mouse kidneys || 1 -0.47 -0.64 -0.48 -0.12 -1.12 -1.14 -0.14 -0.35 -0.64 -0.42 -0.25 -0.44 0.36 -0.58 -0.40 0.02
12791 || orf19.1684 || || || Ortholog of C. dubliniensis CD36 : Cd36_81500, C. parapsilosis CDC317 : CPAR2_503620, Candida tenuis NRRL Y-1498 : CANTEDRAFT_93693 and Debaryomyces hansenii CBS767 : DEHA2D15268g || 1 -0.18 -0.10 -0.39 -0.09 -0.97 -1.17 -0.37 -0.13 -0.60 -0.16 -0.42 -0.49 0.05 -0.31 -0.50 -0.05
12792 || orf19.1843 || ALG6 || || Putative glucosyltransferase involved in cell wall mannan biosynthesis; transcription is elevated in chk1, nik1, and sln1 homozygous null mutants; repressed by nitric oxide; possibly essential gene, disruptants not obtained by UAU1 method || 1 -0.02 -0.17 -0.98 -0.46 -1.32 -1.39 -0.43 -0.23 -0.84 -0.34 -0.12 -0.27 -0.06 -0.53 -1.01 0.25
12793 || orf19.3051 || || || Protein of unknown function; S. pombe ortholog SPAC17A2.02c plays a role in resistance to cadmium; colony morphology-related gene regulation by Ssn6; Spider biofilm repressed || 1 -0.46 -0.36 -1.33 0.04 -1.06 -1.67 -0.61 -0.32 -0.60 -0.18 0.21 0.07 -0.65 -0.23 -0.99 0.13
12794 || orf19.6536 || IQG1 || || Actomyosin ring component at bud neck; cell-cycle regulated ser phosphorylation at CDK sites regulate association with Bni1/Bnr1, Iqg1 degradation, and ring disassembly; mutation causes cytokinetic defects; rat catheter biofilm repressed || 1 -0.46 -0.54 -1.97 -0.42 -0.73 -1.58 -0.24 -0.11 -0.74 -0.09 0.25 -0.43 -0.09 -0.27 -0.95 -0.30
12795 || orf19.6536 || IQG1 || || Actomyosin ring component at bud neck; cell-cycle regulated ser phosphorylation at CDK sites regulate association with Bni1/Bnr1, Iqg1 degradation, and ring disassembly; mutation causes cytokinetic defects; rat catheter biofilm repressed || 1 -0.40 -0.68 -1.10 -0.59 -0.55 -1.42 -0.54 -0.09 -0.95 -0.25 0.32 -0.31 -0.15 -0.22 -0.64 0.10
12796 || orf19.231 || APL2 || || Phosphorylated protein of unknown function; mutation confers hypersensitivity to toxic ergosterol analog || 1 -0.98 -0.85 -1.16 -0.90 -0.40 -1.54 -0.78 -0.62 -0.56 0.10 -0.47 -0.38 -0.07 -0.04 -0.67 0.00
12797 || orf19.3207 || CCN1 || || G1 cyclin; required for hyphal growth maintenance (not initiation); cell-cycle regulated transcription (G1/S); Cdc28p-Ccn1p initiates Cdc11p S394 phosphorylation on hyphal induction; expression in S. cerevisiae inhibits pheromone response || 1 -0.61 -0.45 -0.81 -0.73 -0.38 -2.11 -0.37 -0.59 -0.57 0.05 -0.18 0.12 0.00 0.20 -0.79 -0.18
12798 || orf19.7428 || APN1 || || Ortholog of S. cerevisiae Apn1; an AP endonuclease; transcript induced by interaction with macrophages; fungal-specific (no human or murine homolog) || 1 -0.32 -0.53 -0.55 -0.50 -0.33 -0.98 -0.20 0.00 -0.32 0.09 -0.24 0.02 -0.20 0.34 -0.24 -0.04
12799 || orf19.3423 || TIF3 || || Putative translation initiation factor; genes encoding ribosomal subunits, translation factors, and tRNA synthetases are downregulated upon phagocytosis by murine macrophage || 1 -0.43 -0.47 -0.59 -0.61 -0.58 -0.88 -0.36 0.18 -0.58 0.65 0.19 -0.19 -0.10 0.20 -0.23 -0.06
12800 || orf19.2216 || PDS5 || || Putative protein with a predicted role in establishment and maintenance of sister chromatid condensation and cohesion; cell-cycle regulated periodic mRNA expression || 1 -0.78 -0.92 -0.93 -0.59 -1.12 -1.71 -0.53 0.17 -0.64 0.49 0.15 -0.27 -0.03 0.05 -0.48 0.13
12801 || orf19.2216 || PDS5 || || Putative protein with a predicted role in establishment and maintenance of sister chromatid condensation and cohesion; cell-cycle regulated periodic mRNA expression || 1 -0.80 -1.01 -0.59 -0.47 -1.28 -1.87 -0.99 -0.01 -0.66 0.53 0.12 -0.38 -0.19 0.29 -0.56 -0.11
12802 || orf19.3126 || CCT6 || || Putative cytosolic chaperonin Cct ring complex subunit; mutation confers hypersensitivity to cytochalasin D; GlcNAc-induced protein; Spider biofilm repressed || 1 -0.53 -0.44 -0.34 -0.45 -0.38 -0.69 -0.49 -0.00 -0.44 0.34 -0.14 -0.07 -0.26 -0.15 -0.25 0.13
12803 || orf19.3031 || SEC62 || || Putative endoplasmic reticulum (ER) protein-translocation complex subunit || 1 -0.41 -0.42 -0.72 -0.52 -0.76 -1.41 -0.64 0.08 -0.48 0.49 -0.24 -0.19 -0.76 -0.40 -0.49 -0.19
12804 || orf19.6642 || || || Ortholog(s) have role in ER to Golgi vesicle-mediated transport, cellular response to nitrogen starvation, negative regulation of G0 to G1 transition || 1 -0.64 -0.64 -0.56 -0.42 -0.94 -0.98 -0.45 -0.44 -0.97 -0.63 -0.32 -0.41 -0.29 -1.13 -0.43 -0.50
12805 || orf19.3548 || || || Ortholog(s) have mitochondrion localization || 1 -0.38 -0.48 -0.50 -0.51 -1.07 -0.82 -0.63 -0.59 -0.95 -0.57 -0.11 -0.13 -0.62 -0.72 -0.74 -0.34
12806 || orf19.4356 || HGT3 || || Putative glucose transporter of the major facilitator superfamily; the C. albicans glucose transporter family comprises 20 members; 12 probable membrane-spanning segments, extended C terminus; expressed in rich medium with 2% glucose || 1 -0.36 -0.43 -0.20 -0.44 -0.70 -0.57 -0.24 -0.39 -0.06 -0.46 -0.44 -0.22 -0.56 -0.55 -0.37 -0.01
12807 || orf19.4356 || HGT3 || || Putative glucose transporter of the major facilitator superfamily; the C. albicans glucose transporter family comprises 20 members; 12 probable membrane-spanning segments, extended C terminus; expressed in rich medium with 2% glucose || 1 -0.74 -0.62 -0.65 -0.34 -1.09 -0.63 -0.31 -0.49 -0.07 -0.52 -0.41 -0.03 -0.63 -0.86 -0.55 -0.28
12808 || orf19.4356 || HGT3 || || Putative glucose transporter of the major facilitator superfamily; the C. albicans glucose transporter family comprises 20 members; 12 probable membrane-spanning segments, extended C terminus; expressed in rich medium with 2% glucose || 1 -0.87 -0.94 -0.56 -0.38 -1.37 -0.64 -0.33 -0.46 -0.00 -0.49 -0.34 0.38 -0.91 -0.63 -0.57 0.08
12809 || orf19.4356 || HGT3 || || Putative glucose transporter of the major facilitator superfamily; the C. albicans glucose transporter family comprises 20 members; 12 probable membrane-spanning segments, extended C terminus; expressed in rich medium with 2% glucose || 1 -1.02 -1.08 -1.06 -0.71 -1.42 -0.89 -0.45 -0.56 -0.40 -0.40 -0.47 0.01 -1.14 -0.84 -0.39 0.17
12810 || orf19.4356 || HGT3 || || Putative glucose transporter of the major facilitator superfamily; the C. albicans glucose transporter family comprises 20 members; 12 probable membrane-spanning segments, extended C terminus; expressed in rich medium with 2% glucose || 1 -0.73 -0.56 -0.25 -0.02 -1.01 -0.33 -0.42 -0.52 -0.17 -0.41 -0.36 0.50 -1.01 -0.56 -0.37 0.12
12811 || orf19.3548 || || || Ortholog(s) have mitochondrion localization || 1 -0.32 -0.27 -0.33 -0.23 -1.08 -0.68 -0.54 -0.41 -0.68 -0.52 -0.05 0.19 -0.83 -0.49 -0.73 0.29
12812 || orf19.2923 || || || Predicted membrane transporter, member of the drug:proton antiporter (14 spanner) (DHA2) family, MFS superfamily; induced by alpha pheromone in SpiderM medium || 1 -0.64 -0.74 -0.30 -0.44 -1.60 -1.28 -0.39 -0.51 -0.48 -0.64 0.11 0.40 -0.68 -0.59 -0.54 -0.05
12813 || orf19.4525 || || || Ortholog(s) have endoplasmic reticulum, nuclear pore localization || 1 -0.58 -0.68 -0.54 -0.37 -0.96 -0.56 -0.72 -0.46 -0.64 -0.31 -0.15 0.14 -0.61 -0.08 0.06 -0.25
12814 || orf19.4525 || || || Ortholog(s) have endoplasmic reticulum, nuclear pore localization || 1 -0.76 -0.92 -0.83 -0.62 -1.32 -0.89 -0.85 -0.64 -0.98 -0.66 -0.45 -0.38 -0.96 -0.33 -0.20 -0.40
12815 || orf19.3565 || || || Ortholog of C. dubliniensis CD36 : Cd36_19830, C. parapsilosis CDC317 : CPAR2_206470, Candida tenuis NRRL Y-1498 : CANTEDRAFT_113899 and Debaryomyces hansenii CBS767 : DEHA2C05676g || 1 -0.70 -0.76 -0.84 -0.73 -0.87 -0.56 -0.54 -0.42 -0.68 -0.26 -0.09 -0.28 -0.45 -0.40 -0.13 -0.03
12816 || orf19.7025 || MCM1 || || Transcription factor; regulator of hyphal growth; may act with Wor1p; canonical and non-canonical binding sites; MADS domain DNA-binding motif; similar to S. cerevisiae Mcm1p; greater expression in white than opaque cells; intron in 5'-UTR || 1 -0.81 -1.11 -0.70 -0.53 -0.82 -0.47 -0.89 -0.47 -0.93 -0.59 0.05 -0.00 -0.67 -0.60 -0.24 -0.32
12817 || orf19.7025 || MCM1 || || Transcription factor; regulator of hyphal growth; may act with Wor1p; canonical and non-canonical binding sites; MADS domain DNA-binding motif; similar to S. cerevisiae Mcm1p; greater expression in white than opaque cells; intron in 5'-UTR || 1 -0.74 -0.92 -0.74 -0.48 -0.71 -0.35 -0.61 -0.32 -0.63 -0.43 0.14 0.32 -0.43 -0.53 -0.08 0.04
12818 || orf19.1674 || CDC53 || || Cullin, a scaffold subunit of the SCF ubiquitin-ligase complexes; depletion leads to increased filamentous growth and premature cell death || 1 -0.71 -0.70 -0.64 -0.63 -0.91 -0.93 -0.30 -0.25 -0.58 -0.48 -0.02 0.12 -0.35 -0.43 -0.28 -0.21
12819 || orf19.1663 || MNT2 || || Alpha-1,2-mannosyl transferase; adds 3rd mannose in cell-wall mannoprotein biosynthesis; partially redundant with Mnt1; role in adherence and virulence; expressed in yeast and hyphae; fungal-specific; Hap43-induced; Spider biofilm induced || 1 -0.65 -0.90 -0.80 -0.30 -1.26 -1.15 -0.63 -0.19 -0.80 -0.03 0.15 0.37 -0.38 -0.30 0.01 -0.10
12820 || orf19.3622 || ANP1 || || Putative mannosyltransferase of Golgi; member of Mnn9p family; similar to S. cerevisiae Anp1p; fungal-specific (no human or murine homolog) || 1 -0.85 -1.03 -0.68 -0.36 -1.35 -0.73 -0.36 -0.21 -0.73 -0.09 -0.24 0.22 -0.33 -0.18 -0.13 0.02
12821 || orf19.4956 || RPN1 || || Putative 19S regulatory particle of the 26S proteasome; regulated by Gcn2p and Gcn4p || 1 -0.53 -0.75 -0.52 -0.47 -0.75 -0.92 -0.38 -0.30 -0.40 -0.26 -0.25 0.08 -0.50 -0.28 0.10 0.25
12822 || orf19.5175 || || || Ortholog(s) have ubiquitin-protein ligase activity, role in ER-associated ubiquitin-dependent protein catabolic process and Doa10p ubiquitin ligase complex, integral to endoplasmic reticulum membrane, nuclear inner membrane localization || 1 -0.66 -0.77 -0.65 -0.36 -0.58 -0.59 -0.48 -0.25 -0.28 -0.01 -0.37 0.17 -0.74 -0.27 0.17 0.10
12823 || orf19.4112 || || || Ortholog(s) have 8-oxo-dGDP phosphatase activity, ATP binding, magnesium ion binding, thiamine binding, thiamine diphosphokinase activity, role in thiamine biosynthetic process and cytosol localization || 1 -0.44 -0.17 -0.48 -0.69 -0.87 -0.67 -0.22 0.03 -0.23 -0.03 -0.25 -0.06 -0.84 -0.04 -0.19 -0.07
12824 || orf19.4112 || || || Ortholog(s) have 8-oxo-dGDP phosphatase activity, ATP binding, magnesium ion binding, thiamine binding, thiamine diphosphokinase activity, role in thiamine biosynthetic process and cytosol localization || 1 -0.72 -0.65 -1.16 -1.11 -1.23 -0.85 -0.11 -0.08 -0.73 0.10 -0.21 -0.16 -0.89 -0.48 -0.35 -0.03
12825 || orf19.6698 || || || Ortholog(s) have asparagine-tRNA ligase activity, role in mitochondrial asparaginyl-tRNA aminoacylation and mitochondrion localization || 1 -0.38 -0.59 -0.53 -1.03 -0.72 -0.90 0.12 -0.16 -0.60 -0.36 -0.32 -0.22 -0.61 -0.46 -0.23 -0.18
12826 || orf19.2039 || MSF1 || || Putative phenylalanine-tRNA ligase; protein level decreases in stationary phase cultures; Hap43p-repressed gene || 1 -0.43 -0.75 -1.03 -1.18 -0.77 -0.90 -0.12 0.21 -0.05 -0.06 -0.03 -0.46 -0.33 -0.56 -0.70 -0.64
12827 || orf19.4932 || || || Ortholog(s) have role in mitochondrial translation and mitochondrion localization || 1 -1.34 -1.47 -2.15 -1.88 -1.46 -1.65 0.05 -0.02 -0.38 0.20 -0.37 -0.85 -1.13 -1.42 -0.50 -0.51
12828 || orf19.5085 || || || Ortholog(s) have nuclear localization sequence binding, protein transporter activity and role in mRNA export from nucleus, protein import into nucleus, regulation of mitosis, regulation of protein desumoylation || 1 -0.77 -0.87 -0.87 -0.88 -0.66 -0.95 -0.46 0.02 -0.85 0.11 -0.04 -0.69 -0.88 -0.29 -0.62 -0.49
12829 || orf19.3960 || HYS2 || || Putative DNA polymerase III (delta) subunit with a predicted role in DNA replication and DNA repair; cell-cycle regulated periodic mRNA expression || 1 -1.15 -1.43 -1.45 -1.25 -1.16 -1.96 -0.83 -0.15 -1.08 0.05 -0.03 -1.16 -1.43 -0.90 -1.47 -0.59
12830 || orf19.3838 || EFB1 || || Translation elongation factor EF-1 beta; repressed by human whole blood or PMNs; macrophage/pseudohyphal-induced; antigenic in mouse; farnesol-downregulated; snoRNA snR18 is encoded within the EFB1 intron; Spider biofilm repressed || 1 -0.66 -0.47 -0.91 -0.75 -0.73 -1.03 -0.05 -0.05 -0.44 0.15 -0.20 -0.53 -0.94 -0.61 -0.97 -0.60
12831 || orf19.3838 || EFB1 || || Translation elongation factor EF-1 beta; repressed by human whole blood or PMNs; macrophage/pseudohyphal-induced; antigenic in mouse; farnesol-downregulated; snoRNA snR18 is encoded within the EFB1 intron; Spider biofilm repressed || 1 -0.42 -0.54 -1.13 -1.04 -0.72 -1.18 0.01 -0.13 -0.43 -0.19 -0.11 -0.72 -0.96 -0.69 -0.93 -0.53
12832 || orf19.6105 || MVD || || Mevalonate diphosphate decarboxylase; functional homolog of S. cerevisiae Erg19; possible drug target; regulated by carbon source, yeast-hypha switch, growth phase, antifungals; gene has intron; rat catheter, Spider biofilm repressed || 1 -0.93 -0.88 -0.84 -0.48 -0.74 -0.88 0.06 0.35 -0.26 -0.07 0.04 -0.73 -0.88 -0.54 -1.02 -0.56
12833 || orf19.2146 || HAT2 || || Putative Hat1-Hat2 histone acetyltransferase complex subunit; role in DNA damage repair and morphogenesis; mutations cause constitutive pseudohyphal growth, caspofungin sensitivity; rat catheter and Spider biofilm repressed || 1 -0.91 -0.95 -0.81 -0.56 -0.65 -1.23 -0.37 0.36 -0.52 -0.14 0.39 -0.66 -0.68 -0.31 -1.41 -0.47
12834 || orf19.2929 || GSC1 || || Essential beta-1,3-glucan synthase subunit; gsc1 allele determines resistance/sensitivity to echinocandins; 16 predicted membrane-spanning regions; mRNA abundance declines after yeast-to-hypha transition; Spider biofilm induced || 1 -0.94 -0.99 -0.68 -0.31 -1.09 -1.04 -0.38 0.12 -0.47 -0.02 -0.57 -0.69 -0.54 0.12 -0.51 -0.48
12835 || orf19.6131 || KSR1 || || 3-ketosphinganine reductase, catalyzes the second step in phytosphingosine synthesis || 1 -0.56 -0.62 -0.23 0.01 -1.13 -1.20 -0.31 -0.18 -0.19 0.14 -0.77 -0.47 -0.64 -0.79 -0.73 -0.36
12836 || orf19.1160 || || || Ortholog(s) have COPII adaptor activity and role in ER to Golgi vesicle-mediated transport, fungal-type cell wall organization, protein glycosylation, protein retention in Golgi apparatus || 1 -0.57 -0.61 -0.09 0.03 -1.27 -1.42 -0.55 -0.26 -0.33 -0.15 -0.66 -0.47 -0.73 -0.68 -1.06 -0.50
12837 || orf19.52 || || || Ortholog(s) have role in cellular iron ion homeostasis and mitochondrion localization || 1 -0.51 -0.52 -0.13 -0.04 -0.89 -0.97 -0.50 -0.38 -0.15 -0.12 -0.51 -0.20 -0.72 -0.62 -0.95 -0.45
12838 || orf19.3951 || TIP1 || || Protein with a predicted role in biogenesis of ER-derived COPII transport vesicles; mutation confers hypersensitivity to toxic ergosterol analog || 1 -0.66 -0.90 -0.21 -0.31 -1.31 -1.33 -1.21 -0.60 -0.87 -0.02 -0.45 -0.15 -1.22 -0.76 -1.05 -0.44
12839 || orf19.3951 || TIP1 || || Protein with a predicted role in biogenesis of ER-derived COPII transport vesicles; mutation confers hypersensitivity to toxic ergosterol analog || 1 -0.72 -0.79 -0.30 -0.30 -0.92 -1.22 -0.82 -0.43 -0.66 -0.00 -0.19 -0.04 -0.83 -0.57 -0.58 -0.51
12840 || orf19.1160 || || || Ortholog(s) have COPII adaptor activity and role in ER to Golgi vesicle-mediated transport, fungal-type cell wall organization, protein glycosylation, protein retention in Golgi apparatus || 1 -0.80 -0.95 -0.24 -0.26 -0.73 -1.37 -0.67 -0.25 -0.30 0.02 -0.46 -0.25 -0.80 -0.40 -1.00 -0.48
12841 || orf19.5693 || || || Subunit of the GPI (glycosylphosphatidylinositol):protein transamidase complex; removes the GPI-anchor signal and attaches GPI to proteins in the ER; Spider biofilm repressed || 1 -0.41 -0.35 -0.18 -0.20 -0.19 -0.72 -0.40 -0.19 -0.18 -0.04 -0.15 -0.16 -0.39 -0.19 -0.42 -0.26
12842 || orf19.1418 || SEC15 || || Predicted exocyst subunit; cellular bud tip-associated protein; ortholog of S. cerevisiae SEC15 || 1 -0.31 -0.40 -0.44 -0.47 -0.56 -0.78 -0.41 -0.37 -0.21 -0.21 -0.39 -0.35 -0.47 0.01 -0.44 -0.22
12843 || orf19.2198 || FLC3 || || Protein involved in heme uptake; putative FAD transporter, similar to S. cerevisiae Flc3p || 1 -0.26 -0.57 -0.73 -0.20 -1.71 -1.42 -0.46 -0.63 -0.70 0.08 -0.74 -0.82 -0.29 -0.12 -0.77 -0.46
12844 || orf19.473 || TPO4 || || Putative sperimidine transporter; fungal-specific (no human or murine homolog); Spider biofilm induced; promoter bound by Tec1 and Ndt80; Bcr1-repressed in RPMI a/a biofilms || 1 -0.34 -0.34 -0.54 -0.28 -0.80 -1.14 -0.27 -0.31 -0.30 -0.39 -0.21 -0.22 -0.08 -0.07 -0.61 -0.21
12845 || orf19.9 || || || Ortholog of C. dubliniensis CD36 : Cd36_32700, C. parapsilosis CDC317 : CPAR2_204280, Candida tenuis NRRL Y-1498 : CANTEDRAFT_113831 and Debaryomyces hansenii CBS767 : DEHA2E03916g || 1 -0.58 -0.48 -0.49 -0.46 -1.27 -1.47 -0.50 -0.32 -0.17 -0.49 -0.39 -0.49 0.11 0.11 -0.84 -0.27
12846 || orf19.3174 || CDC24 || || GDP-GTP exchange factor for Cdc42p; phosphorylated; required for maintenance of hyphal growth; misexpression blocks hyphal growth and causes avirulence in a mouse model of systemic infection; antigenic during human oral infection || 1 -0.60 -0.61 -0.18 0.00 -1.57 -1.60 -0.56 -0.14 -0.57 -0.21 -1.07 -1.00 -0.15 -0.01 -1.16 -0.81
12847 || orf19.4608 || PDC12 || || Putative pyruvate decarboxylase; fungal-specific (no human or murine homolog) || 1 -0.53 -0.51 -0.39 -0.05 -1.26 -1.44 -0.30 -0.08 -0.32 -0.25 -0.70 -0.74 -0.19 0.05 -1.03 -0.31
12848 || orf19.1680 || TFP1 || || Subunit of vacuolar H+-ATPase; stationary phase enriched protein; sumoylation target; Spider biofilm repressed || 1 -0.37 -0.31 -0.39 -0.18 -1.34 -1.21 -0.14 -0.22 -0.35 -0.37 -0.42 -0.64 -0.16 -0.25 -0.91 -0.42
12849 || orf19.1133 || MSB1 || || Putative regulator of transcription; expression in S. cerevisiae flo8 and flo11 mutants suggests a role in regulation of adhesion factors || 1 -0.72 -0.60 -0.36 -0.16 -1.49 -1.98 -0.79 -0.36 -0.65 -0.40 -0.52 -0.78 -0.77 -0.04 -1.64 -0.19
12850 || orf19.758 || || || Ortholog(s) have signal sequence binding activity, role in vacuolar transport and late endosome localization || 1 -0.41 -0.48 -0.49 -0.34 -1.16 -1.44 -0.70 -0.43 -0.51 -0.42 -0.81 -0.67 -1.01 -0.25 -1.60 -0.69
12851 || orf19.1897 || || || Ortholog of C. dubliniensis CD36 : Cd36_21640, C. parapsilosis CDC317 : CPAR2_105040, Candida tenuis NRRL Y-1498 : CANTEDRAFT_112352 and Debaryomyces hansenii CBS767 : DEHA2C08008g || 1 -1.15 -1.23 -0.74 -0.30 -2.61 -1.78 -1.27 -0.70 -0.85 -0.64 -0.33 -0.29 -1.04 -0.51 -1.74 -0.25
12852 || orf19.6863 || VPH1 || || Vacuolar H(+)-ATPase; transcription regulated by Nrg1, Mig1, and Tup1 || 1 -0.50 -0.64 -0.44 -0.22 -1.26 -1.11 -0.46 -0.47 -0.31 -0.27 -0.31 -0.06 -0.54 -0.13 -0.53 -0.12
12853 || orf19.5007 || ACT1 || || Actin; gene has intron; transcript regulated by growth phase, starvation; at polarized growth site in budding and hyphal cells; required for wild-type Cdc42 localization; unprocessed N terminus; Hap43-induced; Spider biofilm repressed || 1 -0.61 -0.74 -0.69 -0.39 -1.55 -1.15 -0.32 -0.68 -0.60 -0.61 -0.46 -0.52 -0.29 -0.63 -0.74 -0.30
12854 || orf19.1628 || LAP41 || || Putative aminopeptidase yscI precursor; mutant is viable; protein present in exponential and stationary growth phase yeast cultures; Spider biofilm repressed || 1 -0.50 -0.69 -0.84 -0.54 -1.84 -1.51 -0.17 -0.42 -0.43 -0.49 -0.55 -0.47 -0.99 -0.30 -0.97 0.05
12855 || orf19.6846 || PHO85 || || Functional homolog of S. cerevisiae Pho85p, a cyclin-dependent kinase that regulates transcription of PHO genes involved in phosphate metabolism; necessary for geldanamycin-induced filamentation; gene has intron || 1 -0.16 -0.25 -0.52 -0.33 -1.30 -0.88 -0.03 0.02 -0.21 -0.30 -0.09 -0.34 -0.49 -0.19 -0.81 -0.10
12856 || orf19.1064 || ACS2 || || Acetyl-CoA synthetase; antigenic during human and murine infection; induced by Efg1; macrophage-induced protein; soluble protein in hyphae; gene contains intron; flow model and Spider biofilm repressed || 1 -0.54 -0.55 -1.29 -0.94 -2.23 -2.48 0.02 0.21 -0.60 -0.35 0.21 -0.37 -1.28 -0.26 -1.70 0.03
12857 || orf19.5004 || RAD54 || || Putative DNA-dependent ATPase involved in DNA repair; induced under hydroxyurea treatment; plays an essential role during mitotic growth; mutants display aberrant cell and nuclear morphology || 1 -0.60 -0.66 -0.99 -1.03 -1.51 -1.62 -0.52 -0.18 -0.52 -0.48 -0.05 -0.26 -0.99 -0.13 -1.13 0.06
12858 || orf19.6740 || || || Ortholog(s) have ubiquitin-protein ligase activity and role in generation of catalytic spliceosome for first transesterification step || 1 -0.83 -0.65 -1.02 -0.98 -1.08 -0.76 -0.52 -0.07 -0.74 -0.51 0.00 -0.68 -0.62 -0.15 -1.03 -0.22
12859 || orf19.806 || VMA7 || || Putative subunit of the V-ATPase complex, which is involved in control of vacuolar pH; highly similar to S. cerevisiae Vma7p; interacts with phosphatidylinositol 3-kinase Vps34p || 1 -0.36 -0.52 -0.67 -0.54 -0.80 -0.87 -0.45 -0.11 -0.77 -0.43 -0.15 -0.36 -0.78 -0.06 -0.67 -0.33
12860 || orf19.3534 || RHO3 || || Putative Rho family GTPase; possible substrate of protein farnesyltransferase and geranylgeranyltransferase type I; greater transcription in hyphal form than yeast form; plasma membrane-localized || 1 -0.63 -0.61 -0.82 -0.55 -1.61 -1.51 -0.61 -0.09 -0.94 -0.24 -0.32 -0.67 -0.39 -0.24 -1.03 -0.57
12861 || orf19.5861 || KRE9 || || Protein of beta-1,6-glucan biosynthesis; required for serum-induced hyphal growth; required for efficient utilization of galactose and for growth on glucose; similar to S. cerevisiae Kre9p and Knh1p; O-glycosylated by Pmt1p || 1 -0.39 -0.66 -0.34 -0.54 -0.80 -0.75 -0.35 -0.01 -0.26 -0.10 -0.20 -0.09 -0.50 -0.24 -0.33 -0.06
12862 || orf19.3247 || || || Putative ortholog of S. cerevisiae Laa1p; likely to be essential for growth, based on an insertional mutagenesis strategy || 1 -0.46 -0.51 -0.46 -0.49 -0.56 -0.94 -0.25 -0.19 -0.28 0.01 -0.22 -0.06 -0.46 -0.05 -0.25 -0.17
12863 || orf19.6131 || KSR1 || || 3-ketosphinganine reductase, catalyzes the second step in phytosphingosine synthesis || 1 -0.50 -0.55 -0.40 -0.45 -0.64 -0.90 -0.17 -0.12 -0.18 0.06 -0.37 -0.23 -0.33 -0.27 -0.40 -0.12
12864 || orf19.6930 || SOL1 || || Cell cycle regulator; partial functional homolog of S. cerevisiae Sic1p; protein degradation regulated by SCF(CDC4) pathway; CDK phosphorylation predicted || 1 -1.06 -1.10 -1.13 -0.59 -1.33 -1.42 -0.53 -0.43 -0.91 -0.37 -0.35 -0.62 -0.66 -0.86 -1.00 -0.44
12865 || orf19.7538 || || || DNA helicase involved in rDNA replication; Spider biofilm repressed || 1 -1.27 -1.15 -0.90 -0.78 -1.49 -2.14 -0.41 -0.03 -0.89 -0.60 -0.06 -0.66 -1.02 -0.67 -1.71 -0.01
12866 || orf19.3496 || CHC1 || || Clathrin heavy chain; subunit of the major coat protein; role in intracellular protein transport and endocytosis; flow model and rat catheter biofilm repressed || 1 -0.49 -0.52 -0.41 -0.66 -0.95 -1.02 -0.28 -0.03 -0.63 -0.37 0.08 -0.40 -0.28 -0.10 -0.54 -0.01
12867 || orf19.4732 || SEC24 || || Protein with a possible role in ER to Golgi transport; induced upon yeast-hyphal switch; sumoylation target; Spider biofilm repressed || 1 -0.83 -0.93 -0.67 -0.64 -1.27 -1.30 -0.31 -0.26 -0.57 -0.55 -0.14 -0.38 -0.62 -0.17 -0.64 -0.07
12868 || orf19.3496 || CHC1 || || Clathrin heavy chain; subunit of the major coat protein; role in intracellular protein transport and endocytosis; flow model and rat catheter biofilm repressed || 1 -0.74 -0.73 -1.00 -0.82 -1.30 -1.29 -0.28 -0.32 -0.91 -0.66 -0.07 -0.68 -0.48 -0.42 -0.37 -0.18
12869 || orf19.3409 || SEC12 || || Putative guanyl-nucleotide exchange factor; induced in high iron; Hap43-repressed || 1 -0.86 -0.54 -0.64 -0.57 -0.82 -1.02 -0.09 -0.07 -0.54 -0.28 -0.05 -0.45 -0.60 -0.13 -0.32 0.03
12870 || orf19.1834 || || || Ortholog of C. dubliniensis CD36 : Cd36_09960, C. parapsilosis CDC317 : CPAR2_212580, Debaryomyces hansenii CBS767 : DEHA2G11770g and Pichia stipitis Pignal : PICST_51041 || 1 -0.62 -0.80 -0.82 -1.27 -1.18 -1.78 -0.50 -0.12 -0.62 -0.18 -0.27 -0.39 -0.17 -0.15 -1.23 0.01
12871 || orf19.1244 || GYP2 || || Ortholog(s) have Rab GTPase activator activity, role in intracellular protein transport and cell division site, cytosol localization || 1 -0.42 -0.42 -0.69 -0.55 -0.95 -0.81 -0.17 -0.21 0.04 0.03 -0.48 -0.33 -0.28 -0.18 -0.54 -0.15
12872 || orf19.905 || AVT7 || || Ortholog of S. cerevisiae Avt7 transporter; repressed upon adherence to polystyrene; constitutive expression independent of MTL or white-opaque status; Spider biofilm induced || 1 -0.67 -0.86 -0.90 -0.67 -1.44 -1.60 -0.49 -0.11 -0.17 -0.28 -0.78 -0.81 -0.94 -0.39 -1.00 -0.85
12873 || orf19.3994 || || || Dolichyl-diphosphooligosaccharide-protein glycotransferase; predicted role in protein N-linked glycosylation, protein O-linked mannosylation; Spider biofilm repressed || 1 -0.69 -0.75 -1.52 -0.34 -1.39 -1.75 -0.12 0.02 -0.24 -0.13 -0.55 -0.61 -0.89 -0.51 -0.98 -0.79
12874 || orf19.4633 || || || Ortholog(s) have carbonyl reductase (NADPH) activity, oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor activity and cytosol, nucleus, ribosome localization || 1 -0.28 -0.39 -0.63 -0.55 -1.22 -0.86 -0.05 -0.24 -0.24 -0.44 -0.25 -0.57 -0.77 -0.66 -1.07 -0.38
12875 || orf19.5367 || RDH54 || || Putative DNA-dependent ATPase with a predicted role in DNA recombination and repair; transcriptionally induced by interaction with macrophages || 1 -0.43 -0.50 -0.52 -0.32 -1.04 -1.24 -0.37 -0.13 -0.22 0.21 0.14 -0.44 -0.87 -0.36 -0.78 -0.14
12876 || orf19.6863 || VPH1 || || Vacuolar H(+)-ATPase; transcription regulated by Nrg1, Mig1, and Tup1 || 1 -0.36 -0.46 -0.25 -0.12 -1.21 -1.01 -0.33 -0.38 -0.07 -0.14 -0.11 -0.15 -0.24 -0.25 -0.86 -0.54
12877 || orf19.4633 || || || Ortholog(s) have carbonyl reductase (NADPH) activity, oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor activity and cytosol, nucleus, ribosome localization || 1 -0.44 -0.50 -0.49 -0.16 -1.16 -0.96 -0.20 -0.07 0.18 -0.33 0.02 0.01 -0.75 -0.29 -0.99 -0.46
12878 || orf19.5300 || || || Calnexin; integral membrane ER chaperone involved in folding and quality control of glycoproteins; caspofungin induced || 1 -0.15 -0.44 -0.17 -0.06 -0.71 -0.56 -0.19 0.12 0.26 -0.02 0.08 -0.02 -0.28 -0.16 -0.44 -0.32
12879 || orf19.7136 || SPT6 || || Putative transcription elongation factor; transposon mutation affects filamentous growth; transcript induced in an RHE model of oral candidiasis and in clinical isolates from oral candidiasis || 1 -0.37 -0.44 -0.03 -0.09 -0.24 -0.41 -0.31 -0.09 0.03 -0.06 0.08 0.05 -0.44 -0.07 -0.43 -0.27
12880 || orf19.2302 || || || Ortholog(s) have enzyme regulator activity, role in cellular calcium ion homeostasis and integral to endoplasmic reticulum membrane localization || 1 -0.71 -1.00 -0.45 -0.54 -0.98 -0.83 -0.34 -0.01 -0.16 0.17 -0.03 0.15 -0.57 -0.11 -0.43 -0.64
12881 || orf19.3347 || RPB7 || || Functional homolog of S. cerevisiae Rpb7; essential subunit of RNA Polymerase II; enhances hyperfilamentation of an S. cerevisiae rpb4 mutant; suppresses defects of S. cerevisiae rpb4 and ess1 mutants; Spider biofilm repressed || 1 -0.45 -0.54 -0.28 -0.44 -0.57 -0.79 -0.37 0.05 -0.15 -0.13 -0.03 0.12 -0.12 -0.01 -0.24 -0.39
12882 || orf19.1970 || || || Putative vacuole biogenesis protein || 1 -0.62 -0.47 -0.10 -0.21 -0.43 -1.08 -0.32 0.01 -0.22 -0.02 0.04 0.10 -0.32 -0.24 -0.08 -0.27
12883 || orf19.1637 || || || Ortholog(s) have cytosol, nucleus localization || 1 -0.94 -0.60 -0.45 -0.25 -0.94 -1.35 -0.63 -0.33 0.06 -0.08 0.06 0.16 -0.79 -0.41 -0.50 -0.40
12884 || orf19.3152 || AMO2 || || Protein similar to A. niger predicted peroxisomal copper amino oxidase; mutation confers hypersensitivity to toxic ergosterol analog; F-12/CO2 early biofilm induced || 1 -1.16 -1.21 -0.92 -0.48 -1.13 -1.77 -0.44 -0.48 -0.62 -0.52 -0.06 0.73 -0.75 -0.35 -1.47 -0.78
12885 || orf19.3152 || AMO2 || || Protein similar to A. niger predicted peroxisomal copper amino oxidase; mutation confers hypersensitivity to toxic ergosterol analog; F-12/CO2 early biofilm induced || 1 -0.78 -0.69 -0.62 -0.36 -0.61 -1.31 -0.18 -0.14 -0.06 0.08 0.04 1.08 -0.73 -0.26 -0.93 -0.35
12886 || orf19.6011 || SIN3 || || Protein similar to S. cerevisiae Sin3p (transcriptional corepressor involved in histone deacetylase recruitment); has paired amphipathic helix PAH1 domain; interacts with ScOpi1p, not CaOpi1p; transposon mutation affects filamentous growth || 1 -0.37 -0.67 -0.50 -0.52 -0.44 -0.58 -0.46 -0.13 -0.23 -0.19 -0.12 0.01 -0.41 0.27 -0.56 -0.17
12887 || orf19.5234 || RBD1 || || Rhomboid-like protein; similar to putative intramembrane serine proteases; role in filamentous growth; Gcn4-regulated; caspofungin repressed; Spider biofilm induced || 1 -0.26 -0.31 -0.16 -0.41 -0.43 -0.50 -0.32 -0.07 0.06 -0.12 0.07 -0.05 -0.23 0.31 -0.34 -0.09
12888 || orf19.1092 || || || Dolichol-P-Man dependent alpha(1-3) mannosyltransferase; role in the synthesis of dolichol-linked oligosaccharide donor for N-linked glycosylation of proteins; rat catheter biofilm repressed || 1 -0.40 -0.55 -0.22 -0.39 -1.13 -0.84 -0.31 -0.03 0.13 0.17 -0.39 0.17 -0.35 0.26 -0.80 -0.28
12889 || orf19.6863 || VPH1 || || Vacuolar H(+)-ATPase; transcription regulated by Nrg1, Mig1, and Tup1 || 1 -0.44 -0.48 -0.45 -0.34 -1.00 -0.94 -0.44 -0.44 -0.00 0.02 -0.29 0.12 -0.25 0.17 -0.33 0.02
12890 || orf19.6634 || VMA2 || || Vacuolar H(+)-ATPase; protein present in exponential and stationary growth phase yeast cultures; plasma membrane localized; amphotericin B repressed, caspofungin repressed || 1 -0.56 -0.40 -0.46 -0.34 -0.99 -0.64 -0.12 -0.18 -0.16 -0.04 -0.18 0.08 -0.30 0.46 -0.37 0.10
12891 || orf19.2352 || || || Ortholog(s) have mitochondrion localization || 1 -0.68 -0.37 -0.64 -0.71 -1.16 -0.88 -0.22 -0.11 0.01 0.34 -0.06 0.32 -0.38 0.12 -0.53 0.01
12892 || orf19.5644 || || || Ortholog(s) have role in ascospore wall assembly, spore membrane bending pathway and cytoplasm, prospore membrane localization || 1 -1.18 -1.18 -0.89 -0.93 -1.83 -1.21 -0.50 -0.46 0.14 -0.80 -0.31 0.21 -0.60 -0.03 -0.60 -0.21
12893 || orf19.4811 || || || Putative tricarboxylate carrier family protein; localized to the mitochondrial membrane || 1 -0.42 -0.49 -0.35 -0.27 -0.76 -0.58 -0.15 -0.15 0.47 -0.20 -0.27 -0.01 -0.48 -0.03 -0.40 0.05
12894 || orf19.6131 || KSR1 || || 3-ketosphinganine reductase, catalyzes the second step in phytosphingosine synthesis || 1 -0.61 -0.66 -0.29 -0.29 -1.02 -0.93 -0.31 -0.28 -0.06 0.48 -0.55 -0.32 -0.56 0.04 -0.59 0.09
12895 || orf19.4981 || || || Ortholog(s) have endoplasmic reticulum localization || 1 -0.69 -0.97 -0.02 0.00 -1.26 -1.00 -0.69 -0.23 0.09 0.53 -0.73 -0.18 -0.58 -0.46 -0.76 -0.20
12896 || orf19.2746 || EMP70 || || Protein with a role in endosome-to-vacuole sorting; rat catheter biofilm repressed || 1 -0.70 -0.72 -0.46 -0.13 -0.91 -1.08 -0.90 -0.13 0.53 -0.21 -0.10 -0.48 -0.05 -0.51 -0.47
12897 || orf19.4080 || || || Putative ribonuclease H2 subunit; required for RNase H2 activity; repressed in Spider biofilms by Bcr1, Tec1, Brg1, Rob1 || 1 -0.70 -0.59 -0.43 -0.27 -1.21 -0.98 -0.66 -0.56 -0.03 0.64 -0.25 0.03 -0.43 -0.01 -0.84 -0.26
12898 || orf19.7621 || || || Putative subunit of an alternative replication factor C complex; role in DNA replication, genome integrity, homologous recombination-mediated repair and telomere homeostasis; || 1 -0.82 -0.97 -0.80 -0.32 -0.89 -1.31 -0.43 -0.37 -0.18 0.55 -0.16 -0.10 -1.05 0.06 -1.16 -0.60
12899 || orf19.7621 || || || Putative subunit of an alternative replication factor C complex; role in DNA replication, genome integrity, homologous recombination-mediated repair and telomere homeostasis; || 1 -0.40 -0.38 -0.33 0.14 -0.65 -0.77 -0.39 -0.07 -0.07 0.35 -0.18 -0.08 -0.87 -0.06 -0.61 -0.25
12900 || orf19.2302 || || || Ortholog(s) have enzyme regulator activity, role in cellular calcium ion homeostasis and integral to endoplasmic reticulum membrane localization || 1 -0.81 -0.66 -0.20 0.20 -1.09 -0.98 -0.45 0.19 0.13 0.36 -0.30 0.00 -0.83 -0.20 -0.43 -0.49
12901 || orf19.6219 || || || Ortholog of C. dubliniensis CD36 : Cd36_06470, C. parapsilosis CDC317 : CPAR2_208960, Candida tenuis NRRL Y-1498 : CANTEDRAFT_114040 and Pichia stipitis Pignal : PICST_51125 || 1 -0.78 -0.94 -0.79 0.38 -1.33 -2.04 -0.18 0.08 -0.03 0.35 -0.59 -0.30 -0.76 -0.08 -1.09 -0.45
12902 || orf19.1832 || FCY23 || || Putative transporter; Gcn4p-regulated; more similar to S. cerevisiae Tpn1p, which is a vitamin B6 transporter, than to purine-cytosine permeases || 1 -0.57 -0.47 -0.46 0.06 -0.68 -1.39 0.02 -0.21 0.05 -0.28 0.05 0.28 -0.25 -0.23 -0.21 -0.11
12903 || orf19.3952 || SRP101 || || Signal recognition particle (SRP) receptor alpha subunit; involved in SRP-dependent protein targeting; rat catheter biofilm repressed || 1 -0.19 -0.38 -0.13 -0.01 -0.50 -0.86 -0.20 0.06 -0.09 0.14 -0.13 0.13 -0.36 -0.23 -0.10 -0.09
12904 || orf19.3774 || PPG1 || || Putative protein phosphatase of the Type 2A-related family (serine/threonine-specific), similar to S. cerevisiae Ppg1p; possibly an essential gene, disruptants not obtained by UAU1 method || 1 -0.68 -0.53 -0.25 -0.16 -1.57 -1.44 -0.56 -0.13 -0.35 0.09 -0.43 0.06 -0.39 -0.75 0.03 -0.50
12905 || orf19.2618 || MET2 || || Homoserine acetyltransferase; Hap43p-, Gcn4p-regulated; macrophage/pseudohyphal-repressed; not highly biofilm induced, in contrast to many sulfur amino acid metabolic genes; no human or murine homolog; virulence-group-correlated expression || 1 -0.64 -0.61 -0.77 -0.23 -2.08 -1.82 -0.40 -0.57 0.29 -0.64 0.09 -0.14 -0.73 -0.85 -0.16 -0.77
12906 || orf19.7381 || AHR1 || || Zn(II)2Cys6 transcription factor; involved in regulation of adhesion genes; involved in white-opaque switch; forms complex with Mcm1; mutant is sensetive to 5-fluorocytosine and lithium chloride; Spider biofilm induced || 1 -0.51 -0.45 -0.23 0.32 -2.09 -2.32 -0.51 -0.76 -0.23 -0.51 -0.09 0.32 -0.58 -0.27 -0.81 -1.06
12907 || orf19.1663 || MNT2 || || Alpha-1,2-mannosyl transferase; adds 3rd mannose in cell-wall mannoprotein biosynthesis; partially redundant with Mnt1; role in adherence and virulence; expressed in yeast and hyphae; fungal-specific; Hap43-induced; Spider biofilm induced || 1 -0.47 -0.48 -1.57 -0.17 -1.16 -0.93 -0.72 -0.61 -0.51 0.12 -0.22 -0.01 -0.82 -0.70 -0.41 -0.79
12908 || orf19.6599.1 || || || Ortholog(s) have role in cytoplasmic translation and cytoplasm, nucleus localization || 1 -0.17 -0.16 -0.68 -0.34 -0.95 -0.54 -0.21 -0.10 -0.43 0.17 -0.16 0.09 -0.48 0.12 -0.24 -0.32
12909 || orf19.5200 || SIT4 || || Serine/threonine protein phosphatase catalytic subunit; has a role in cell wall maintenance, hyphal growth, and virulence in a mouse systemic infection model || 1 -0.06 -0.26 -0.76 -0.49 -0.56 -0.50 -0.32 -0.05 -0.25 -0.06 -0.39 -0.22 -0.39 0.11 0.08 -0.31
12910 || orf19.3449.2 || || || Putative mitochondrial phosphatidylglycerophosphatase (PGP phosphatase); essential for cardiolipin biosynthesis; rat catheter biofilm induced || 1 -0.92 -0.58 -0.77 -0.53 -0.69 -0.98 -0.13 -0.39 -0.13 0.37 -0.59 -0.28 0.06 0.13 -0.69 -0.20
12911 || orf19.651 || LYP1 || || Putative permease; amphotericin B induced; flucytosine repressed; possibly an essential gene, disruptants not obtained by UAU1 method || 1 -1.69 -1.41 -1.44 -1.20 -1.61 -1.65 -0.40 -0.73 -0.12 -0.27 -1.66 -0.68 -0.60 0.11 -1.00 -0.76
12912 || orf19.5585 || SAP5 || || Secreted aspartyl proteinase; sap4,5,6 triple null defective in utilization of protein as N source; virulence role effected by URA3; expressed during infection; mRNA localized to hyphal tip via She3; rat catheter and Spider biofilm induced || 1 -0.82 -0.77 -1.02 -0.66 -0.99 -0.83 0.00 -0.75 0.23 -0.31 -1.25 -0.33 -0.48 0.46 -0.15 -0.06
12913 || orf19.1911 || PGA52 || || GPI-anchored cell surface protein of unknown function; Hap43p-repressed gene; fluconazole-induced; possibly an essential gene, disruptants not obtained by UAU1 method || 1 -1.00 -0.64 -0.45 -0.50 -0.89 -0.53 -0.19 -0.37 -0.25 -0.99 -0.98 -0.50 -0.05 -0.13 -0.38 -0.18
12914 || orf19.4515 || || || Predicted protein with similarity to cell wall proteins; possibly an essential gene, disruptants not obtained by UAU1 method || 1 -0.75 -0.47 -0.20 -0.37 -0.85 -0.76 -0.23 -0.47 0.08 -0.69 -0.77 -0.61 0.09 -0.03 -0.81 0.08
12915 || orf19.31 || || || Ortholog of C. parapsilosis CDC317 : CPAR2_201960, C. dubliniensis CD36 : Cd36_20900, Candida tropicalis MYA-3404 : CTRG_04756 and Candida albicans WO-1 : CAWG_04394 || 1 -0.92 -1.04 -0.32 -0.43 -1.06 -0.86 -0.62 -0.43 -0.02 -0.47 -0.77 -0.27 -0.16 0.35 -0.38 0.25
12916 || orf19.6852 || || || Ortholog of Rmd6 involved in S. cerevisiae sporulation; flow model biofilm induced || 1 -0.41 -0.40 -0.50 -0.50 -0.60 -0.74 -0.44 -0.13 -0.13 -0.69 -0.41 -0.16 -0.35 -0.04 -0.50 0.08
12917 || orf19.4776 || LYS143 || || Zn(II)2Cys6 transcription factor; ortholog of S. cerevisiae Lys14 involved in the regulation of lysine biosynthesis genes || 1 -0.46 -0.27 -0.15 -0.47 -0.64 -1.03 -0.41 -0.59 0.05 -0.47 -0.97 -0.15 -0.58 -0.04 -0.29 -0.05
12918 || orf19.2064 || || || Putative transcription factor with zinc finger DNA-binding motif || 1 -0.93 -0.82 -0.22 -0.66 -0.82 -0.14 -0.34 -0.61 -0.14 -0.58 -1.53 -0.37 -0.75 -0.12 -0.61 -0.06
12919 || orf19.1459 || PPE1 || || Protein similar to S. cerevisiae Ppe1p; shows genetic interaction with some genes involved in diploid filamentous growth and haploid invasive growth in S. cerevisiae || 1 -0.47 -0.64 -0.43 -0.27 -0.43 -0.04 -0.23 -0.02 0.04 -0.04 -0.23 -0.15 -0.78 -0.37 -0.55 -0.32
12920 || orf19.3057 || || || Ortholog(s) have role in mitochondrial genome maintenance and endoplasmic reticulum localization || 1 -0.85 -1.02 -0.71 -0.41 -0.45 -0.99 -0.71 -0.27 -0.13 0.52 -0.06 0.02 -1.22 -0.60 -0.97 -0.61
12921 || orf19.4839 || || || GET complex subunit; expression downregulated in an ssr1 null mutant || 1 -0.32 -0.63 -0.57 -0.32 -0.32 -0.31 -0.37 -0.12 -0.27 0.12 -0.39 -0.11 -0.68 -0.17 -0.56 -0.60
12922 || orf19.516 || || || S. cerevisiae ortholog Rft1p has role in glycolipid translocation, protein N-linked glycosylation and localizes to endoplasmic reticulum membrane; regulated by Sef1p-, Sfu1p-, and Hap43p || 1 -1.10 -1.11 -1.56 -0.83 -0.65 -1.00 -0.53 -0.18 0.04 -0.01 -0.65 -0.09 -0.90 -0.67 -0.73 -0.91
12923 || orf19.516 || || || S. cerevisiae ortholog Rft1p has role in glycolipid translocation, protein N-linked glycosylation and localizes to endoplasmic reticulum membrane; regulated by Sef1p-, Sfu1p-, and Hap43p || 1 -0.65 -0.93 -0.42 -0.26 -0.65 -1.09 -0.38 -0.11 0.25 -0.13 -0.63 -0.34 -0.80 -0.43 -0.59 -0.60
12924 || orf19.3293 || || || Putative enoyl reductase involved in very long chain fatty acid elongation; possibly an essential gene, disruptants not obtained by UAU1 method || 1 -1.33 -1.50 -0.99 -0.68 -0.75 -0.84 -0.73 -0.36 -0.44 -0.03 -0.08 -0.01 -0.69 -0.49 0.32 -1.04
12925 || orf19.7625 || PGA1 || || Putative GPI-anchored protein; induced during cell wall regeneration; required for normal adhesion to host cells and for adherence during Sabouraud biofilm formation; Spider biofilm induced || 1 -0.78 -1.13 -0.88 -0.62 -0.68 -0.67 -1.07 -0.12 -0.46 0.23 0.01 0.08 -0.63 -0.51 -0.05 -1.30
12926 || orf19.7625 || PGA1 || || Putative GPI-anchored protein; induced during cell wall regeneration; required for normal adhesion to host cells and for adherence during Sabouraud biofilm formation; Spider biofilm induced || 1 -0.95 -1.00 -0.43 -0.58 -0.82 -0.62 -1.07 -0.21 -0.33 0.47 -0.15 0.01 -0.67 -0.96 -0.31 -0.72
12927 || orf19.2307 || || || Ortholog(s) have role in mRNA cleavage, mRNA polyadenylation, mitotic sister chromatid segregation, regulation of G1/S transition of mitotic cell cycle and cytosol, mRNA cleavage and polyadenylation specificity factor complex localization || 1 -0.41 -0.50 -0.46 -0.29 -0.27 -0.35 -0.63 -0.67 -0.24 0.22 -0.20 0.07 -0.50 -0.57 -0.19 -0.63
12928 || orf19.1120 || FAV2 || || Adhesin-like protein; induced by mating factor in MTLa/a opaque cells, in cyr1 null, in filaments; regulated by Nrg1, Rfg1, Tup1, Tec1, Efg1, Ntd80, Rob1, Brg1; induced in oralpharyngeal candidasis; Spider biofilm induced || 1 -1.85 -1.92 -2.31 -1.78 -0.70 -1.32 -0.51 -0.22 0.04 0.78 0.23 0.23 -1.65 -2.57 -0.19 -2.11
12929 || orf19.1120 || FAV2 || || Adhesin-like protein; induced by mating factor in MTLa/a opaque cells, in cyr1 null, in filaments; regulated by Nrg1, Rfg1, Tup1, Tec1, Efg1, Ntd80, Rob1, Brg1; induced in oralpharyngeal candidasis; Spider biofilm induced || 1 -1.90 -2.14 -2.58 -1.53 -0.87 -1.37 -0.46 -0.06 0.15 0.89 0.33 0.07 -1.53 -2.57 -0.22 -2.26
12930 || orf19.4365 || || || Has domain(s) with predicted RNA methyltransferase activity and role in RNA processing || 1 -1.13 -1.01 -0.99 -1.47 -0.31 -0.57 -0.22 -0.45 -0.53 -0.06 0.15 0.47 -1.36 -1.36 0.09 -0.60
12931 || orf19.4365 || || || Has domain(s) with predicted RNA methyltransferase activity and role in RNA processing || 1 -1.12 -1.39 -2.07 -1.21 -0.47 -0.36 -0.14 -0.86 -0.85 0.16 -0.31 0.80 -1.45 -1.26 0.10 -0.58
12932 || orf19.304 || || || Putative transporter similar to MDR proteins; fungal-specific; Spider biofilm induced || 1 -0.60 -0.78 -1.05 -0.69 -0.48 -0.12 -0.35 -0.18 -0.41 0.40 -0.26 0.49 -1.43 -0.39 0.14 -0.09
12933 || orf19.3314 || TRS20 || || Ortholog(s) have role in ER to Golgi vesicle-mediated transport and TRAPP complex, cytosol, nucleus localization || 1 -0.75 -0.69 -1.15 -0.98 0.05 -0.46 -0.54 0.05 -0.23 -0.63 0.19 -0.41 -0.50 -0.73 -1.12 -0.19
12934 || orf19.3314 || TRS20 || || Ortholog(s) have role in ER to Golgi vesicle-mediated transport and TRAPP complex, cytosol, nucleus localization || 1 -0.53 -0.73 -1.15 -1.30 -0.10 -0.58 -0.43 -0.05 -0.49 -0.73 0.04 -0.41 -0.49 -0.32 -0.99 -0.27
12935 || orf19.1883 || YCS4 || || Putative condensin complex subunit; cell-cycle regulated periodic mRNA expression || 1 -0.67 -0.86 -1.46 -0.52 -0.11 -0.90 -0.33 -0.33 -0.50 -0.51 -0.18 -0.63 -0.52 0.21 -1.46 -0.49
12936 || orf19.7265 || || || Putative zinc-finger domain protein with a predicted role in pre-mRNA splicing; Hap43-repressed; Spider biofilm repressed || 1 -0.84 -0.95 -0.81 -0.63 -0.13 -0.12 0.00 -0.05 0.01 -0.52 0.45 -0.02 -0.57 -0.60 -0.57 -0.09
12937 || orf19.3822 || SCS7 || || Putative ceramide hydroxylase; regulated by Nrg1; induced in high iron; fluconazole-induced; Hap43-repressed; Spider biofilm induced || 1 -0.72 -0.88 -0.73 -1.42 -0.52 -0.71 0.20 -0.06 -0.22 -0.86 0.10 -0.52 -0.60 -0.89 -0.74 0.49
12938 || orf19.317 || PNP1 || || Purine nucleoside phosphorylase; metabolizes inosine and guanosine nucleosides; in the nicotinamide riboside salvage pathway; Spider biofilm repressed || 1 -0.24 -0.17 -0.13 -0.24 -0.31 -0.13 -0.04 -0.01 0.01 -0.18 0.05 -0.17 -0.61 0.01 -0.35 -0.28
12939 || orf19.7600 || FDH3 || || Glutathione-dependent formaldehyde dehydrogenase; glycine catabolism; repressed by Efg1 in yeast, not hyphal growth conditions; induced by Mnl1 under weak acid stress; Spider biofilm repressed || 1 -0.73 -0.72 -0.63 -0.69 -0.92 -0.49 0.17 0.12 -0.41 -1.36 -0.30 -0.69 -1.38 -0.46 -0.92 -0.49
12940 || orf19.7095 || || || Ortholog(s) have endoplasmic reticulum localization || 1 -1.03 -0.94 -0.43 -0.52 -0.96 -0.18 0.05 -0.28 0.57 -0.67 -0.16 -0.03 -1.02 -0.05 -0.57 0.12
12941 || orf19.3113 || || || Protein of unknown function; Spider biofilm induced || 1 -0.19 -0.64 -0.43 -0.66 -0.58 -0.40 0.42 0.09 0.49 -0.25 -0.24 0.17 -0.63 0.18 -0.57 0.26
12942 || orf19.2525 || LYS12 || || Homoisocitrate dehydrogenase; catalyzes 4th step in the alpha-aminoadipate pathway of lysine biosynthesis; clade-associated gene expression; protein level decreases in stationary phase cultures; Spider biofilm repressed || 1 -0.75 -0.76 -0.68 -0.74 -1.38 -0.86 0.67 -0.10 0.64 -0.93 -0.53 -0.19 -1.30 -0.22 -1.18 0.39
12943 || orf19.6699 || || || Ortholog(s) have histidinol-phosphatase activity, role in histidine biosynthetic process and cytosol, nucleus localization || 1 -0.50 -0.56 -0.79 -0.77 -1.22 -0.85 0.34 0.24 -0.13 -0.41 -0.33 -0.31 -0.76 -0.23 -0.62 0.00
12944 || orf19.2601 || HEM1 || || Putative 5-aminolevulinate synthase; caspofungin repressed; induced by high iron, nitric oxide; regulated by Ssn6; Hap43-repressed; Spider biofilm induced || 1 -1.03 -1.03 -1.33 -1.49 -1.61 -1.05 0.48 -0.27 -0.20 -0.67 -1.13 -0.85 -0.68 -0.46 -0.66 -0.54
12945 || orf19.270 || || || Ortholog of C. parapsilosis CDC317 : CPAR2_102150, C. dubliniensis CD36 : Cd36_82780, Pichia stipitis Pignal : psti_CGOB_00155 and Candida orthopsilosis Co 90-125 : CORT_0B03450 || 1 -1.04 -0.83 -1.42 -1.29 -0.96 -1.62 0.55 -0.03 0.57 -0.22 -1.08 0.16 -0.89 -0.22 -0.75 -0.37
12946 || orf19.2098 || ARO8 || || Aromatic transaminase of the Ehrlich fusel oil pathway of aromatic alcohol biosynthesis; Rim101 independent alkaline induction; protein abundance affected by URA3 expression in CAI-4 strain; Gcn4-regulated; stationary phase enriched || 1 -2.10 -1.80 -1.90 -1.52 -2.34 -2.12 0.74 0.16 0.96 -1.17 -0.92 -0.79 -0.98 -0.50 -1.72 -0.73
12947 || orf19.2098 || ARO8 || || Aromatic transaminase of the Ehrlich fusel oil pathway of aromatic alcohol biosynthesis; Rim101 independent alkaline induction; protein abundance affected by URA3 expression in CAI-4 strain; Gcn4-regulated; stationary phase enriched || 1 -1.02 -1.27 -0.99 -0.95 -1.52 -1.46 0.80 0.32 1.27 -0.80 -0.76 -0.18 -0.80 0.03 -1.02 -0.55
12948 || orf19.2601 || HEM1 || || Putative 5-aminolevulinate synthase; caspofungin repressed; induced by high iron, nitric oxide; regulated by Ssn6; Hap43-repressed; Spider biofilm induced || 1 -0.97 -0.92 -0.91 -0.91 -1.40 -0.43 0.47 -0.12 0.36 -0.32 -1.07 -0.26 -0.56 0.19 -0.39 -0.07
12949 || orf19.1584 || || || Predicted MFS membrane transporter; monocarboxylate porter family member; colony morphology-related gene regulation by Ssn6; flow model biofilm induced; Spider biofilm induced || 1 -1.05 -1.12 -0.63 -0.63 -1.64 -1.07 0.17 -0.37 0.86 -1.07 -0.79 -1.15 -1.22 0.02 -2.13 -0.65
12950 || orf19.5263 || SER33 || || Predicted enzyme of amino acid biosynthesis; Gcn4p-regulated; upregulated in biofilm; protein present in exponential and stationary growth phase yeast cultures; S. cerevisiae ortholog is Gcn4p regulated || 1 -0.36 -0.45 -0.70 -0.31 -1.08 -0.93 0.46 -0.08 -0.01 -0.59 -0.55 -0.39 -0.93 -0.18 -1.54 -0.26
12951 || orf19.5263 || SER33 || || Predicted enzyme of amino acid biosynthesis; Gcn4p-regulated; upregulated in biofilm; protein present in exponential and stationary growth phase yeast cultures; S. cerevisiae ortholog is Gcn4p regulated || 1 -0.15 -0.25 -0.10 -0.30 -0.96 -0.85 0.44 0.23 0.21 -0.59 -0.55 -0.41 -0.84 -0.01 -1.49 -0.08
12952 || orf19.6987 || DNM1 || || Putative dynamin-related GTPase; transcript upregulated inbRHE model of oral candidiasis; transcript regulated by Nrg1, Mig1, and Tup1 || 1 -0.35 -0.14 -0.46 -0.27 -0.36 -0.50 -0.37 -0.20 -0.27 -0.27 -0.14 -0.36 -0.37 -0.36 -0.11 -0.44
12953 || orf19.2434 || NPL4 || || Putative ubiquitin-binding protein; regulated by Gcn2p and Gcn4p || 1 -0.41 -0.34 -0.70 -0.39 -0.46 -0.69 -0.47 -0.41 -0.56 -0.18 -0.21 -0.42 -0.86 -0.97 -0.05 -0.88
12954 || orf19.1279 || CDS1 || || Protein similar to S. cerevisiae Cds1p; transposon mutation affects filamentous growth || 1 -0.65 -0.70 -1.17 -0.60 -0.63 -1.39 -0.82 -0.08 -1.22 -0.02 -0.18 -0.56 -1.21 -0.79 0.24 -0.77
12955 || orf19.4993 || SEC18 || || Functional homolog of S. cerevisiae Sec18p, which acts in protein transport; conserved ATP binding site; not glycosylated || 1 -0.15 -0.25 -0.48 -0.35 -0.44 -0.67 -0.38 -0.32 -0.72 -0.18 -0.21 -0.29 -0.60 -0.40 0.05 -0.11
12956 || orf19.350 || PRE9 || || Alpha3 (C9) subunit of the 20S proteasome; transcript regulated by Mig1; flow model biofilm repressed || 1 -0.24 -0.17 -0.61 -0.52 -0.61 -0.93 -0.50 -0.26 -0.76 -0.18 0.08 -0.09 -0.61 -0.63 0.32 -0.26
12957 || orf19.1299 || RPN6 || || Putative 26S proteasome subunit; Hap43p-induced gene; regulated by Gcn2p and Gcn4p || 1 -0.25 -0.39 -0.84 -0.64 -0.44 -0.82 -0.49 -0.27 -0.77 -0.14 0.09 0.22 -0.98 -0.34 0.11 -0.00
12958 || orf19.7605 || PUP1 || || Putative beta 2 subunit of the 20S proteasome; macrophage/pseudohyphal-repressed; Spider biofilm repressed || 1 -0.32 -0.19 -0.54 -0.39 -0.21 -0.24 -0.20 -0.24 -0.46 -0.21 0.01 -0.10 -0.71 -0.46 0.47 0.34
12959 || orf19.7605 || PUP1 || || Putative beta 2 subunit of the 20S proteasome; macrophage/pseudohyphal-repressed; Spider biofilm repressed || 1 -0.23 -0.16 -0.70 -0.58 -0.22 -0.47 -0.22 -0.15 -0.54 -0.38 0.11 -0.30 -0.61 -0.57 0.50 0.09
12960 || orf19.7286 || RPN7 || || Subunit of the proteasome regulatory particle; regulated by Gcn2p and Gcn4p; protein present in exponential and stationary growth phase yeast cultures || 1 -0.67 -0.74 -1.13 -0.78 -0.65 -0.82 -0.61 -0.45 -1.14 -0.35 -0.20 -0.48 -0.97 -0.59 0.36 0.10
12961 || orf19.7286 || RPN7 || || Subunit of the proteasome regulatory particle; regulated by Gcn2p and Gcn4p; protein present in exponential and stationary growth phase yeast cultures || 1 -0.69 -0.42 -1.00 -0.96 -0.32 -0.77 -0.18 -0.16 -0.98 -0.29 0.00 -0.27 -0.86 -0.28 0.41 -0.01
12962 || orf19.2727 || GRX3 || || Putative glutaredoxin; flucytosine induced; regulated by Gcn4p; repressed in response to amino acid starvation (3-aminotriazole treatment) || 1 -0.41 -0.35 -0.94 -0.75 -0.37 -0.41 -0.27 -0.19 -0.82 -0.20 0.17 -0.14 -0.22 -0.20 0.10 0.13
12963 || orf19.3006 || GGA2 || || Protein involved in Golgi trafficking; rat catheter and Spider biofilm repressed || 1 -0.58 -0.72 -1.27 -1.10 -0.35 -0.77 -0.24 -0.31 -0.95 -0.68 0.31 -0.19 -0.50 -0.46 0.11 0.36
12964 || orf19.7438 || UBA1 || || Ubiquitin-activating enzyme; protein level decreases in stationary phase cultures || 1 -0.54 -0.54 -0.79 -0.31 -0.05 -0.40 -0.03 -0.06 -0.63 -0.24 0.04 -0.11 -0.52 -0.50 0.23 -0.17
12965 || orf19.4622 || || || Ortholog(s) have role in telomere maintenance, transcription-coupled nucleotide-excision repair, ubiquitin-dependent protein catabolic process and nucleus localization || 1 -0.82 -0.87 -0.92 -0.65 -0.64 -0.87 -0.37 -0.05 -1.00 -0.12 0.50 -0.33 -0.56 -0.66 0.07 -0.34
12966 || orf19.5147 || LMO1 || || Protein involved together with Dck1p and Rac1p in invasive filamentous growth and cell wall integrity; acts upstream of MAP kinase Cek1p; has similarity to human ELMO1 || 1 -0.40 -0.48 -0.88 -0.74 -0.34 -0.77 -0.49 -0.16 -0.65 0.29 0.37 0.30 -0.03 -0.17 0.11 -0.25
12967 || orf19.1280 || SUI1 || || Putative translation initiation factor; flucytosine induced; genes encoding ribosomal subunits, translation factors, and tRNA synthetases are downregulated upon phagocytosis by murine macrophage || 1 -0.49 -0.51 -1.34 -1.05 -0.43 -1.02 -0.38 -0.38 -1.21 -0.09 0.17 0.12 -0.30 -0.35 0.22 -0.31
12968 || orf19.6858 || EDC3 || || Ortholog(s) have role in cytoplasmic mRNA processing body assembly, deadenylation-independent decapping of nuclear-transcribed mRNA and cytoplasmic mRNA processing body localization || 1 -0.33 -0.36 -1.00 -1.12 -0.32 -0.90 -0.16 -0.33 -0.71 -0.22 0.16 -0.14 0.18 -0.64 0.23 -0.51
12969 || orf19.1324 || RAD2 || || Ortholog of S. cerevisiae Rad2, a nucleotide excision repair nuclease; null mutant is extremely sensitive to UV irradiation; transcript induced by interaction with macrophages || 1 -0.63 -0.59 -1.23 -1.19 -0.31 -0.83 -0.50 -0.61 -0.66 -0.50 -0.25 -0.18 -0.24 -0.49 0.32 -0.46
12970 || orf19.3983 || || || Protein with a predicted transcription factor BTF3 domain; flow model biofilm induced || 1 -0.22 -0.37 -1.18 -0.48 -0.75 -0.75 -0.08 -0.15 -0.73 0.25 -0.05 0.06 -0.97 -0.79 0.20 -0.19
12971 || orf19.1453 || SPT5 || || Protein similar to S. cerevisiae Spt5p transcription elongation factor; transposon mutation affects filamentous growth || 1 -0.22 -0.34 -0.54 -0.63 -0.06 -0.71 -0.04 -0.16 -0.29 -0.28 -0.04 0.20 -0.42 -0.51 0.01 -0.17
12972 || orf19.7144 || || || Ortholog(s) have GTPase activity, ribosome binding activity, role in nonfunctional rRNA decay, nuclear-transcribed mRNA catabolic process, no-go decay, ribosome disassembly and cytosol localization || 1 -0.23 -0.23 -0.47 -0.52 -0.00 -0.27 -0.31 -0.20 -0.60 -0.21 0.25 0.21 -0.30 -0.33 -0.03 -0.19
12973 || orf19.410.3 || RIB4 || || Lumazine synthase (6,7-dimethyl-8-ribityllumazine synthase, DMRL synthase); catalyzes the penultimate step in the synthesis of riboflavin; Hap43-induced; rat catheter and Spider biofilm repressed || 1 -0.72 -0.77 -0.53 -0.63 -0.28 -0.73 0.21 -0.17 -0.28 -0.93 0.62 0.46 -0.33 -0.11 -0.34 0.25
12974 || orf19.3008 || COQ4 || || Protein with a putative role in coenzyme Q biosynthesis; transcriptionally induced by interaction with macrophage; Hap43p-repressed gene || 1 -0.91 -0.82 -0.36 -1.11 -0.25 -0.65 -0.05 0.28 0.01 -0.38 0.44 0.31 -0.60 0.09 -0.25 0.02
12975 || orf19.1427 || || || Putative transporter; fungal-specific; Spider biofilm induced || 1 -1.56 -1.20 -0.58 -0.63 -0.61 -0.30 -0.39 -0.03 0.08 -0.45 0.06 0.68 -0.16 0.35 -1.04 0.33
12976 || orf19.2600 || SPC98 || || Putative component of the microtubule-nucleating Tub4p (gamma-tubulin) complex; periodic mRNA expression, peak at cell-cycle S/G2 phase || 1 -0.67 -0.73 -0.47 -0.62 -0.30 -0.71 -0.19 -0.14 -0.47 -0.09 0.19 0.34 0.02 0.29 -0.82 0.13
12977 || orf19.6403 || || || Ortholog(s) have adenyl-nucleotide exchange factor activity, role in SRP-dependent cotranslational protein targeting to membrane, translocation and endoplasmic reticulum localization || 1 -0.43 -0.26 -0.09 -0.42 -0.51 -0.47 -0.25 -0.23 -0.30 0.17 -0.20 0.10 -0.08 -0.09 0.29 0.16
12978 || orf19.1813 || FLC2 || || Protein involved in heme uptake; putative FAD transporter, similar to S. cerevisiae Flc2p || 1 -0.68 -0.56 -0.13 -0.38 -0.23 -0.50 -0.41 -0.45 -0.15 -0.08 -0.07 0.08 -0.43 -0.18 0.07 0.31
12979 || orf19.1813 || FLC2 || || Protein involved in heme uptake; putative FAD transporter, similar to S. cerevisiae Flc2p || 1 -0.50 -0.75 -0.18 -0.29 -0.50 -0.69 -0.63 -0.44 -0.39 -0.25 0.05 -0.05 -0.67 -0.21 0.07 0.38
12980 || orf19.5640 || PEX5 || || Pex5p family protein; required for PTS1-mediated peroxisomal protein import, fatty acid beta-oxidation; similar to S. cerevisiae Pas10p peroxisomal targeting receptor; macrophage/pseudohyphal-repressed; Hap43p-repressed || 1 -0.59 -0.61 -0.39 -0.06 -0.87 -0.95 -0.37 -0.37 -0.39 -0.28 0.07 -0.29 -0.62 -0.16 -0.10 0.31
12981 || orf19.6674 || BTS1 || || Putative geranylgeranyl diphosphate synthase; repressed by benomyl treatment; Spider biofilm induced || 1 -0.28 -0.55 -0.34 -0.29 -1.01 -0.91 -0.48 -0.76 -0.51 0.05 -0.14 0.16 -0.85 -0.14 0.34 0.78
12982 || orf19.7128 || SYS1 || || Putative Golgi integral membrane protein; transcript regulated by Mig1 || 1 -0.10 -0.26 -0.06 0.06 -0.69 -0.58 -0.58 -0.18 -0.22 0.07 0.01 0.13 -0.43 -0.19 0.28 0.18
12983 || orf19.3972 || || || Ortholog(s) have role in ER to Golgi vesicle-mediated transport, Golgi to endosome transport and ER to Golgi transport vesicle, Golgi membrane, endoplasmic reticulum localization || 1 -1.10 -1.36 -0.25 0.19 -1.57 -1.27 -1.38 -0.94 -1.32 0.13 -0.52 0.43 -0.72 -0.80 0.09 -0.34
12984 || orf19.3972 || || || Ortholog(s) have role in ER to Golgi vesicle-mediated transport, Golgi to endosome transport and ER to Golgi transport vesicle, Golgi membrane, endoplasmic reticulum localization || 1 -1.33 -1.21 -0.86 -0.39 -1.41 -1.59 -1.50 -0.92 -1.32 0.25 -0.40 0.29 -0.31 -0.20 -0.15 -0.75
12985 || orf19.3526 || ITR1 || || MFS inositol transporter; uptake of exogenous inositol; 12 transmembrane motifs; expressed in rich medium; fluconazole, caspofungin repressed; possibly essential (UAU1 method); flow model, rat catheter and Spider biofilm induced || 1 -1.67 -1.50 -0.82 -0.44 -1.25 -1.11 -1.68 -1.24 -1.15 -0.18 -0.82 -0.06 -0.32 -0.10 0.35 -0.08
12986 || orf19.3526 || ITR1 || || MFS inositol transporter; uptake of exogenous inositol; 12 transmembrane motifs; expressed in rich medium; fluconazole, caspofungin repressed; possibly essential (UAU1 method); flow model, rat catheter and Spider biofilm induced || 1 -0.96 -0.98 -0.38 -0.12 -0.67 -0.80 -1.10 -0.83 -1.12 -0.24 -0.33 0.05 0.01 0.11 0.31 0.06
12987 || orf19.3681 || || || Ortholog(s) have Ran guanyl-nucleotide exchange factor activity, protein transporter activity || 1 -0.62 -0.61 -0.68 -0.55 -0.70 -0.68 -0.74 -0.53 -0.90 0.10 -0.09 -0.25 -0.21 -0.22 -0.38 -0.08
12988 || orf19.6392 || || || Ortholog of C. dubliniensis CD36 : Cd36_33870, C. parapsilosis CDC317 : CPAR2_204450, Candida tenuis NRRL Y-1498 : CANTEDRAFT_113827 and Debaryomyces hansenii CBS767 : DEHA2E04158g || 1 -0.73 -0.57 -0.63 -0.72 -0.41 -0.47 -0.44 -0.24 -0.62 0.27 0.10 -0.23 0.23 -0.30 -0.10 -0.20
12989 || orf19.1453 || SPT5 || || Protein similar to S. cerevisiae Spt5p transcription elongation factor; transposon mutation affects filamentous growth || 1 -0.45 -0.43 -0.33 -0.38 -0.08 -0.28 -0.40 -0.37 0.05 -0.28 -0.15 -0.13 -0.26 -0.18 -0.10 -0.46
12990 || orf19.4857 || || || Protein with a dual-specificity phosphatase domain; Hap43-induced gene || 1 -0.37 -0.31 -0.02 -0.34 -0.18 -0.30 -0.49 -0.39 0.06 -0.14 -0.42 0.12 -0.17 -0.46 -0.30 -0.56
12991 || orf19.4340 || || || Ortholog of C. dubliniensis CD36 : Cd36_52890, C. parapsilosis CDC317 : CPAR2_501970, Candida tenuis NRRL Y-1498 : CANTEDRAFT_113546 and Debaryomyces hansenii CBS767 : DEHA2E09900g || 1 -0.34 -0.21 -0.15 -0.06 -0.18 -0.52 -0.48 -0.45 -0.18 -0.43 -0.54 0.19 0.01 -0.30 -0.02 -0.77
12992 || orf19.2170 || PHM7 || || Putative transporter; fungal-specific; Hog1-repressed; repressed by 17-beta-estradiol, ethynyl estradiol; Hap43-induced; Spider biofilm induced || 1 -0.44 -0.66 -0.65 -0.11 -1.10 -0.68 -0.47 -0.69 -0.62 -0.18 -0.44 -0.14 -0.12 -0.78 0.01 -1.06
12993 || orf19.994 || || || Protein of unknown function; induced by Mnl1 under weak acid stress; flow model biofilm repressed || 1 -0.60 -0.58 -0.31 -0.04 -0.98 -0.56 -0.51 -0.38 -0.31 -0.51 -0.06 -0.16 -0.88 -0.40 -0.05 -1.08
12994 || orf19.2262 || || || Protein similar to quinone oxidoreductases; induced by benomyl treatment, nitric oxide; oxidative stress-induced via Cap1; stationary-phase enriched protein; Spider biofilm induced || 1 -0.99 -1.19 -0.41 -0.48 -1.36 -0.53 0.03 -0.69 0.39 -0.70 -1.04 -0.31 -0.53 -0.40 0.08 -1.37
12995 || orf19.2906 || PGA41 || || Putative GPI-anchored protein; adhesin-like protein || 1 -1.30 -1.05 -0.52 0.20 -0.93 -0.25 -0.75 -0.84 -0.06 -0.51 -1.02 -0.16 -0.17 -0.52 0.11 -0.31
12996 || orf19.6885 || SPO7 || || Putative regulatory subunit of Nem1-Spo7 phosphatase holoenzyme that regulates nuclear growth by controling phospholipid biosynthesis; induced by alpha pheromone in SpiderM medium || 1 -0.70 -1.06 -0.22 -0.32 -0.71 -0.34 -0.59 -0.89 -0.03 0.13 -0.68 -0.03 -0.34 -0.40 0.11 -0.48
12997 || orf19.2623 || ECM22 || || Zn(II)2Cys6 transcription factor; rat catheter and Spider biofilm induced || 1 -1.08 -1.17 -0.47 -0.52 -0.90 -1.13 -0.19 -1.47 0.20 -0.71 -1.02 -0.11 -0.69 -0.57 0.02 -0.08
12998 || orf19.2623 || ECM22 || || Zn(II)2Cys6 transcription factor; rat catheter and Spider biofilm induced || 1 -0.84 -0.93 -0.32 -0.33 -1.18 -0.85 -0.23 -1.40 0.19 -0.78 -1.02 -0.04 -0.50 -0.80 -0.03 0.00
12999 || orf19.7648 || || || Has domain(s) with predicted antiporter activity, drug transmembrane transporter activity, role in drug transmembrane transport and membrane localization || 1 -1.29 -1.46 -1.21 -0.82 -2.01 -1.43 -0.88 -1.36 0.10 -0.09 -0.53 0.72 -0.99 -0.97 0.07 -0.24
13000 || orf19.7648 || || || Has domain(s) with predicted antiporter activity, drug transmembrane transporter activity, role in drug transmembrane transport and membrane localization || 1 -1.02 -1.05 -1.14 -0.81 -1.49 -1.13 -0.44 -0.97 0.12 -0.00 -0.30 0.76 -0.64 -0.99 0.24 -0.34
13001 || orf19.3237 || || || Ortholog(s) have cytosol, mitochondrion, nucleus localization || 1 -0.47 -0.38 -0.69 -0.65 -0.39 -0.34 -0.14 -0.50 0.03 -0.41 -0.73 -0.09 -0.54 -0.52 0.07 -0.03
13002 || orf19.4506 || LYS22 || || Putative homocitrate synthase; repressed by nitric oxide and by hypoxia; protein level decreases in stationary phase cultures; induced by ketoconazole, Spider biofilm induced; flow model biofilm repressed || 1 -0.50 -0.34 -0.54 -0.33 -0.87 -0.51 0.85 -0.26 0.82 -0.34 -0.30 -0.02 -0.80 -0.56 0.05 -0.05
13003 || orf19.4506 || LYS22 || || Putative homocitrate synthase; repressed by nitric oxide and by hypoxia; protein level decreases in stationary phase cultures; induced by ketoconazole, Spider biofilm induced; flow model biofilm repressed || 1 -0.95 -0.87 -1.18 -0.55 -1.37 -0.81 0.52 -0.35 0.70 -0.39 -0.35 -0.17 -1.11 -0.66 -0.11 -0.59
13004 || orf19.4506 || LYS22 || || Putative homocitrate synthase; repressed by nitric oxide and by hypoxia; protein level decreases in stationary phase cultures; induced by ketoconazole, Spider biofilm induced; flow model biofilm repressed || 1 -1.08 -1.13 -1.44 -0.63 -1.66 -0.89 0.86 -0.14 0.58 -0.46 -0.18 0.16 -1.60 -0.85 0.29 -0.45
13005 || orf19.4506 || LYS22 || || Putative homocitrate synthase; repressed by nitric oxide and by hypoxia; protein level decreases in stationary phase cultures; induced by ketoconazole, Spider biofilm induced; flow model biofilm repressed || 1 -0.79 -0.96 -1.04 -0.51 -1.62 -0.75 1.11 0.22 1.15 0.09 -0.06 0.48 -1.17 -0.50 0.04 -0.28
13006 || orf19.6632 || ACO2 || || Putative aconitate hydratase 2; induced in high iron; regulated by Gcn4; repressed by amino acid starvation (3-AT); protein levels decrease in stationary phase yeast; flow model and Spider biofilm repressed || 1 -0.72 -0.74 -1.21 -0.51 -1.35 -0.96 0.62 0.68 0.81 0.38 0.17 0.33 -1.55 -0.91 -0.01 -0.02
13007 || orf19.4040 || ILV3 || || Dihydroxyacid dehydratase; repressed by nitric oxide; macrophage-induced protein; protein in exponential and stationary growth phase; Sef1, Sfu1p, Hap43-regulated; farnesol-repressed; flow model biofilm induced; Spider biofilm repressed || 1 -1.37 -1.38 -1.43 -1.05 -1.37 -0.97 0.82 0.34 0.51 0.27 0.53 0.47 -1.54 -0.89 -0.42 -0.04
13008 || orf19.4040 || ILV3 || || Dihydroxyacid dehydratase; repressed by nitric oxide; macrophage-induced protein; protein in exponential and stationary growth phase; Sef1, Sfu1p, Hap43-regulated; farnesol-repressed; flow model biofilm induced; Spider biofilm repressed || 1 -1.38 -1.48 -1.17 -0.92 -1.58 -1.19 0.74 0.29 0.60 0.22 0.28 0.07 -1.60 -0.73 -0.58 -0.35
13009 || orf19.1403 || || || Ortholog(s) have ATP:ADP antiporter activity, calcium ion binding activity, role in ADP transport, ATP transport, mitochondrial transport and mitochondrion localization || 1 -0.29 -0.29 -0.40 -0.57 -0.54 -0.37 0.47 0.02 0.30 0.38 0.05 0.49 -0.26 -0.22 -0.37 -0.39
13010 || orf19.1948 || || || Ortholog of C. dubliniensis CD36 : Cd36_51110, C. parapsilosis CDC317 : CPAR2_302560, Candida tenuis NRRL Y-1498 : CANTEDRAFT_135271 and Debaryomyces hansenii CBS767 : DEHA2E12914g || 1 -0.45 -0.41 -0.57 -0.38 -0.36 -0.31 0.47 0.35 0.02 -0.19 0.06 0.01 0.28 -0.65 -0.57 0.11
13011 || orf19.767 || ERG3 || || C-5 sterol desaturase; introduces C-5(6) double bond into episterol; some clinical isolates show increased azole resistance and defects in hyphal growth and virulence; Efg1p-repressed; fluconazole-induced || 1 -0.95 -1.23 -1.14 -0.85 -1.42 -0.75 0.83 0.55 0.45 -0.55 0.17 -0.56 0.73 -0.08 -1.29 -0.07
13012 || orf19.5665 || || || Ortholog(s) have D-arabinose 1-dehydrogenase [NAD(P)+] activity and role in dehydro-D-arabinono-1,4-lactone biosynthetic process || 1 -0.35 -0.57 -0.32 -0.05 -0.55 -0.26 0.03 0.17 0.31 0.27 0.42 -0.01 -0.30 -0.08 -0.40 -0.08
13013 || orf19.3227 || FTH2 || || Putative iron transporter; similar to S. cerevisiae Fth1p || 1 -0.45 -0.76 -0.82 -0.23 -0.37 -0.47 0.06 0.23 0.13 1.04 0.14 0.11 -0.22 -0.25 -0.30 -0.44
13014 || orf19.4022 || SDH4 || || Succinate dehydrogenase, membrane subunit; induced in high iron || 1 -0.83 -1.20 -1.19 -0.48 -0.44 -0.27 -0.22 0.37 0.13 0.70 -0.08 0.28 -0.66 -0.44 -0.19 -0.12
13015 || orf19.331 || || || Ortholog(s) have S-adenosylmethionine-dependent methyltransferase activity, protein methyltransferase activity and role in peptidyl-glutamine methylation, regulation of translation || 1 -0.16 -0.17 -0.46 -0.42 -0.50 -0.02 -0.11 0.34 -0.01 0.31 0.20 -0.05 -0.35 -0.56 -0.16 0.10
13016 || orf19.1864 || || || Ortholog(s) have role in ribosome-associated ubiquitin-dependent protein catabolic process and RQC complex, cytosol, cytosolic large ribosomal subunit localization || 1 -0.19 -0.25 -0.44 -0.38 -0.32 -0.31 -0.20 -0.06 0.24 0.12 -0.01 0.05 -0.07 -0.46 -0.03 0.04
13017 || orf19.2541 || || || Ortholog(s) have 3'-5'-exodeoxyribonuclease activity, endonuclease activity, role in apoptotic DNA fragmentation, cellular response to oxidative stress and cytosol, nucleus localization || 1 -0.29 -0.66 -0.81 -0.87 -0.19 0.05 -0.03 -0.15 -0.07 0.32 0.18 -0.20 -0.26 -0.51 -0.27 0.20
13018 || orf19.7577 || MSS51 || || Putative mRNA maturation factor; fungal-specific (no human or murine homolog) || 1 -0.23 -0.42 -0.94 -1.41 -0.21 -0.48 0.05 0.28 0.19 0.13 -0.13 0.01 -0.02 -0.27 -0.47 0.06
13019 || orf19.7577 || MSS51 || || Putative mRNA maturation factor; fungal-specific (no human or murine homolog) || 1 -0.15 -0.03 -1.07 -1.28 -0.14 -0.26 0.15 0.39 0.27 0.18 -0.06 -0.05 -0.14 -0.50 -0.36 0.09
13020 || orf19.137 || || || Putative transferase involved in phospholipid biosynthesis; induced by alpha pheromone in SpiderM medium || 1 -0.19 -0.35 -0.64 -0.73 -0.93 -0.78 0.56 0.07 -0.99 -1.13 0.00 -0.49 0.83 0.37 0.03 0.55
13021 || orf19.137 || || || Putative transferase involved in phospholipid biosynthesis; induced by alpha pheromone in SpiderM medium || 1 -0.20 -0.32 -0.62 -0.74 -0.86 -0.43 0.40 -0.06 -0.71 -0.90 0.31 0.19 0.60 0.52 0.15 0.69
13022 || orf19.4892 || TPK1 || || cAMP-dependent protein kinase catalytic subunit; Tpk2 isoform; control of morphogenesis and stress response; WT nuclear localization requires Bcy1; produced during stationary, not exponential growth; rat catheter and Spider biofilm induced || 1 -0.34 -0.37 -0.60 -0.97 -0.84 -0.78 0.64 -0.27 -0.67 -0.36 0.65 0.05 0.49 0.34 -0.39 0.21
13023 || orf19.5137 || || || Protein of unknown function; regulated by Sef1, Sfu1, Hap43; Spider biofilm repressed || 1 -0.34 -0.56 -0.47 -0.50 -0.45 -1.32 0.08 0.05 -1.11 -0.07 -0.15 0.51 0.94 0.64 -0.06 0.26
13024 || orf19.6718 || || || Has domain(s) with predicted sequence-specific DNA binding activity || 1 -0.19 -0.38 -0.36 -0.26 -0.35 -0.29 0.06 0.11 -0.47 0.01 0.46 0.09 0.02 0.41 -0.16 0.25
13025 || orf19.4265 || UAP1 || || UDP-N-acetylglucosamine pyrophosphorylase, catalyzes biosynthesis of UDP-N-acetylglucosamine from UTP and N-acetylglucosamine 1-phosphate; functional homolog of S. cerevisiae Qri1p; alkaline upregulated || 1 -0.41 -0.83 -0.83 -0.40 -0.45 -0.12 -0.23 -0.31 -0.82 0.30 0.34 0.42 0.16 0.31 -0.25 0.52
13026 || orf19.4265 || UAP1 || || UDP-N-acetylglucosamine pyrophosphorylase, catalyzes biosynthesis of UDP-N-acetylglucosamine from UTP and N-acetylglucosamine 1-phosphate; functional homolog of S. cerevisiae Qri1p; alkaline upregulated || 1 -0.63 -0.71 -0.98 -0.49 -0.94 -0.62 -0.13 -0.42 -0.95 0.05 0.45 0.19 -0.09 0.32 -0.43 -0.20
13027 || orf19.5276 || || || Putative nuclear pore-associated protein; Hap43p-induced gene; induced upon low-level peroxide stress; possibly an essential gene, disruptants not obtained by UAU1 method || 1 -0.43 -0.43 -0.45 -0.40 -0.68 -0.29 0.03 -0.52 -0.62 -0.34 0.00 0.08 -0.15 0.61 -0.58 0.15
13028 || orf19.2429 || || || Protein of unknown function; induced by alpha pheromone in SpiderM medium || 1 -0.24 -0.33 -0.22 -0.86 -0.45 -0.91 0.19 0.44 -0.09 -0.34 -0.56 0.19 -0.54 1.13 -0.39 0.00
13029 || orf19.2383 || YKU80 || || Yku70p-Yku80p Ku complex subunit involved in nonhomologous end joining during double-strand break repair repair; Hap43-repressed gene; flow model biofilm induced || 1 -0.44 -0.06 -1.01 -0.84 -0.04 -1.00 0.20 0.14 0.10 -0.35 -0.25 -0.17 -0.43 0.57 -0.65 -0.09
13030 || orf19.139 || TRA1 || || Subunit of the NuA4 histone acetyltransferase complex || 1 -0.65 -0.77 -0.34 -0.33 -0.28 -0.76 -0.33 0.28 -0.14 0.26 0.47 0.19 -0.61 0.44 0.14 0.41
13031 || orf19.2677 || || || Putative GPI transamidase component; possibly an essential gene, disruptants not obtained by UAU1 method || 1 -0.34 -0.66 -0.20 -0.39 -0.14 -0.63 0.22 0.55 0.07 -0.01 0.20 -0.10 0.23 -0.07 -0.00 0.22
13032 || orf19.7156 || FAA2-3 || || Predicted acyl CoA synthetase || 1 -0.91 -0.81 -1.64 -0.42 0.29 -0.88 0.59 -0.25 -0.16 0.17 -0.12 0.17 -0.63 0.42 0.34 0.11
13033 || orf19.1516 || || || Ortholog(s) have ubiquitin-specific protease activity || 1 -0.18 -0.08 -0.35 -0.00 -0.20 -0.62 0.02 0.18 -0.04 -0.25 0.23 0.10 0.15 -0.29 0.18 0.15
13034 || orf19.7655 || RPO21 || || RNA polymerase II; ortholog of S. cerevisiae Rpo21, transposon mutation affects filamentous growth; flow model biofilm repressed || 1 -0.47 -0.51 -0.48 -0.09 -0.41 -0.63 0.14 0.27 0.05 -0.23 0.56 0.05 -0.00 -0.11 0.37 0.51
13035 || orf19.6109 || TUP1 || || Transcriptional corepressor; represses filamentous growth; regulates switching; role in germ tube induction, farnesol response; in repression pathways with Nrg1, Rfg1; farnesol upregulated in biofilm; rat catheter, Spider biofilm repressed || 1 -0.60 -0.65 -0.19 -0.09 -0.94 -0.50 0.21 0.15 0.15 -0.34 0.23 0.38 -0.20 0.25 0.02 -0.02
13036 || orf19.2204.2 || RHO2 || || Ortholog(s) have GTPase activity || 1 -0.54 -0.69 -0.51 -0.42 -1.02 -0.90 0.15 0.25 0.11 -0.03 -0.14 0.45 0.30 0.35 0.42 0.21
13037 || orf19.1358 || GCN4 || || bZIP transcription factor; amino acid control response; required for Efg1-dependent pseudohyphal induction by amino acid starvation, not by serum; human whole blood and PMN induced; required for biofilm formation; Spider biofilm induced || 1 -0.65 -0.75 -1.02 -0.75 -1.11 -0.69 0.47 -0.01 0.38 -0.77 0.29 0.44 0.22 0.28 0.81 0.42
13038 || orf19.1358 || GCN4 || || bZIP transcription factor; amino acid control response; required for Efg1-dependent pseudohyphal induction by amino acid starvation, not by serum; human whole blood and PMN induced; required for biofilm formation; Spider biofilm induced || 1 -0.50 -0.72 -0.58 -0.25 -1.17 -0.58 0.41 -0.13 0.42 -0.62 0.09 0.34 0.17 0.09 0.59 0.53
13039 || orf19.2325 || || || Ortholog(s) have RNA polymerase III type 1 promoter sequence-specific DNA binding and RNA polymerase III type 1 promoter sequence-specific DNA binding TFIIIB recruiting transcription factor activity, more || 1 -0.58 -0.24 -0.21 -0.25 -0.35 -0.28 0.47 0.15 -0.01 -0.16 0.70 0.32 0.44 0.22 -0.03 0.38
13040 || orf19.3148 || || || Protein of unknown function; possibly an essential gene, disruptants not obtained by UAU1 method || 1 -0.52 -0.32 -0.33 -0.30 -0.54 -0.59 -0.07 0.25 0.04 -0.16 0.43 0.19 0.54 0.28 -0.20 0.28
13041 || orf19.6713 || || || Has domain(s) with predicted nucleic acid binding activity || 1 -0.81 -0.70 -0.30 -0.53 -1.19 -0.81 0.53 0.23 0.66 0.29 1.16 0.69 1.59 0.81 0.55 0.32
13042 || orf19.6713 || || || Has domain(s) with predicted nucleic acid binding activity || 1 -0.83 -0.69 -0.48 -0.57 -1.22 -1.03 0.31 -0.05 0.40 0.28 0.90 0.28 1.33 0.47 0.33 0.08
13043 || orf19.6952 || || || Ortholog(s) have DNA binding, chromatin binding, histone deacetylase activity || 1 -0.20 -0.51 -0.60 -0.37 -0.60 -0.65 0.23 0.05 0.08 -0.12 0.62 0.39 0.53 0.22 0.35 0.24
13044 || orf19.6966 || || || Ortholog(s) have choline kinase activity, ethanolamine kinase activity, role in phosphatidylcholine biosynthetic process, phosphatidylethanolamine biosynthetic process and cytosol, nucleus localization || 1 -0.16 -0.55 -0.30 -0.27 -0.35 -0.52 -0.13 0.41 0.26 -0.04 0.46 0.36 0.61 0.29 0.38 -0.03
13045 || orf19.2163 || || || Ortholog(s) have cytosol localization || 1 -0.34 -0.44 -0.06 -0.19 -0.21 0.06 0.11 0.10 0.31 -0.29 0.38 0.16 0.20 -0.06 0.17 0.40
13046 || orf19.5370 || || || Ortholog(s) have fungal-type vacuole membrane localization || 1 -0.36 -0.40 -0.13 -0.14 -0.25 0.04 0.06 0.17 0.30 -0.36 0.44 0.27 0.12 0.06 0.20 0.26
13047 || orf19.3285 || || || Ortholog of C. dubliniensis CD36 : Cd36_25800, Candida tenuis NRRL Y-1498 : CANTEDRAFT_116265, Debaryomyces hansenii CBS767 : DEHA2E17380g and Pichia stipitis Pignal : PICST_62836 || 1 -0.27 -0.84 -0.38 -0.51 -0.74 0.04 0.03 0.47 0.17 -0.37 0.31 0.80 -0.00 0.34 0.52 1.13
13048 || orf19.5410 || || || Ortholog(s) have microtubule plus-end binding activity and role in conidium formation, nuclear migration along microtubule, regulation of microtubule motor activity, sexual sporulation resulting in formation of a cellular spore || 1 -0.30 -0.44 -0.13 -0.03 -0.33 -0.61 0.05 0.12 0.27 0.57 0.30 0.57 0.16 0.31 0.30 -0.16
13049 || orf19.1382 || YEA4 || || Putative uridine diphosphate-N-acetylglucosamine (UDP-GlcNAc) transporter; required for cell wall chitin synthesis; induced by alpha pheromone in SpiderM medium || 1 -0.44 -0.38 -0.09 -0.21 -0.47 -0.25 -0.04 -0.16 -0.04 0.23 0.30 0.46 0.13 -0.07 0.03 -0.32
13050 || orf19.1207 || || || Ortholog of C. dubliniensis CD36 : Cd36_33200 and Candida albicans WO-1 : CAWG_03416 || 1 -0.69 -0.90 -0.41 -0.79 -1.07 -0.16 0.16 0.21 0.85 0.52 1.41 0.46 0.33 0.22
13051 || orf19.6392 || || || Ortholog of C. dubliniensis CD36 : Cd36_33870, C. parapsilosis CDC317 : CPAR2_204450, Candida tenuis NRRL Y-1498 : CANTEDRAFT_113827 and Debaryomyces hansenii CBS767 : DEHA2E04158g || 1 -0.57 -0.71 -0.56 -0.47 -0.61 -0.29 -0.38 -0.18 -0.28 0.61 0.46 0.56 0.11 0.08 0.32 -0.12
13052 || orf19.3333 || || || Ortholog(s) have poly(A) RNA binding activity, role in mRNA polyadenylation, poly(A)+ mRNA export from nucleus, regulation of mRNA stability and cytoplasm, nucleus localization || 1 -0.40 -0.31 -0.26 -0.38 0.05 -0.12 -0.08 0.23 -0.38 0.44 0.40 0.63 0.21 0.18 0.40 -0.13
13053 || orf19.1441 || || || Ortholog of C. dubliniensis CD36 : Cd36_16230, C. parapsilosis CDC317 : CPAR2_213950, Candida tenuis NRRL Y-1498 : CANTEDRAFT_112720 and Debaryomyces hansenii CBS767 : DEHA2A01848g || 1 -0.55 -0.55 -1.26 -0.82 -0.52 0.11 0.41 -0.06 -0.33 0.54 0.23 0.70 0.84 0.24 0.25 0.18
13054 || orf19.1508 || || || Protein of unknown function; transcript detected on high-resolution tiling arrays || 1 -0.67 -0.67 -0.97 -0.46 -0.38 -0.01 0.09 0.05 0.33 0.22 0.18 0.44 0.76 0.22 -0.09 -0.11
13055 || orf19.5382 || || || Ortholog of Candida albicans WO-1 : CAWG_02410 || 1 -0.41 -0.58 -0.67 -0.26 0.03 0.22 -0.01 -0.05 -0.08 0.35 0.09 0.18 0.56 -0.14 0.10 -0.03
13056 || orf19.3541 || ERF1 || || Putative translation release factor 1, which interacts with stop codons and promotes release of nascent peptides from ribosomes; Hap43p-induced gene || 1 -0.20 -0.04 -0.75 -0.64 0.20 -0.40 -0.43 -0.10 -0.71 0.61 0.24 0.12 -0.07 0.13 -0.04 0.07
13057 || orf19.96 || TOP1 || || DNA topoisomerase I; required for wild-type growth and for wild-type mouse virulence; sensitive to camptothecin; induced upon adherence to polystyrene; rat catheter biofilm induced || 1 -0.05 -0.11 -0.25 -0.10 -0.07 0.02 0.03 0.02 -0.49 0.64 0.63 -0.08 0.04 0.24 -0.61 -0.02
13058 || orf19.96 || TOP1 || || DNA topoisomerase I; required for wild-type growth and for wild-type mouse virulence; sensitive to camptothecin; induced upon adherence to polystyrene; rat catheter biofilm induced || 1 -0.20 -0.17 -0.75 -0.46 -0.13 -0.23 0.41 0.19 -0.61 0.81 0.78 -0.16 0.09 0.23 -0.67 -0.20
13059 || orf19.3129 || || || Putative chromatin remodelling complex protein; heterozygous null mutant displays sensitivity to virgineone; Spider biofilm repressed || 1 0.00 0.03 -0.28 -0.10 -0.09 -0.13 -0.04 0.38 -0.40 0.18 0.44 -0.10 -0.06 0.19 -0.23 0.05
13060 || orf19.3291 || HMT1 || || Major type I protein arginine methyltransferase (PRMT); involved in asymmetric dimethylation of arginine residues; involved in nuclear export of Npl3p; Spider biofilm repressed || 1 0.02 -0.18 -0.71 -0.35 -0.23 -0.70 0.47 1.08 -0.39 0.88 0.40 -0.46 -0.34 0.22 -0.61 0.42
13061 || orf19.506 || YDJ1 || || Putative type I HSP40 co-chaperone; heavy metal (cadmium) stress-induced || 1 -0.26 -0.22 -0.82 -0.52 -0.37 -0.40 -0.04 0.40 -0.58 1.00 0.38 -0.22 -0.21 -0.04 -0.07 -0.54
13062 || orf19.3126 || CCT6 || || Putative cytosolic chaperonin Cct ring complex subunit; mutation confers hypersensitivity to cytochalasin D; GlcNAc-induced protein; Spider biofilm repressed || 1 -0.17 -0.18 -0.55 -0.25 -0.10 -0.45 -0.07 0.58 -0.20 0.87 0.43 -0.02 -0.02 0.07 -0.18 -0.28
13063 || orf19.3552 || || || Ortholog(s) have structural constituent of nuclear pore activity || 1 -0.13 -0.06 -0.28 -0.17 0.19 -0.19 0.13 0.29 -0.20 0.28 0.43 -0.11 0.03 0.25 0.03 -0.14
13064 || orf19.6910 || PSF1 || || Putative GINS complex subunit which is localized to DNA replication origins; implicated in assembly of the DNA replication machinery; flow model biofilm induced || 1 -0.67 -0.55 -1.22 -0.86 0.66 -0.98 -0.07 0.76 -0.19 1.07 0.72 0.13 -0.40 1.11 -0.08 0.05
13065 || orf19.2967 || TIF34 || || Putative translation initiation factor eIF3, p39 subunit; mutation confers hypersensitivity to roridin A, verrucarin A; downregulated upon phagocytosis by murine macrophages; Spider biofilm repressed || 1 0.06 -0.06 -0.66 -0.61 -0.10 -0.66 -0.12 0.50 -0.38 0.27 0.05 -0.06 -0.19 0.26 -0.17 -0.02
13066 || orf19.3288.1 || || || Predicted ORF in Assembly 20 and 21; merged with orf19.3288 in Assembly 21 || 1 0.01 -0.27 -1.26 -0.79 -0.25 -0.44 0.12 0.40 -0.37 0.77 0.22 -0.41 0.02 0.38 -0.27 0.13
13067 || orf19.518 || || || Ortholog(s) have tRNA (cytosine-5-)-methyltransferase activity, role in tRNA methylation and nucleus localization || 1 -0.22 -0.21 -1.11 -1.01 0.43 0.01 0.06 0.58 -0.31 0.90 0.55 -0.15 -0.31 0.19 0.10 0.35
13068 || orf19.1199 || NOP5 || || Ortholog of S. cerevisiae Nop58; involved in pre-rRNA process; Tn mutation affects filamentous growth; macrophage/pseudohyphal-induced; physically interacts with TAP-tagged Nop1; Spider biofilm repressed || 1 -0.14 -0.18 -0.97 -0.75 0.16 0.18 -0.05 0.26 -0.49 0.78 0.58 -0.12 -0.01 0.34 -0.11 0.31
13069 || orf19.1199 || NOP5 || || Ortholog of S. cerevisiae Nop58; involved in pre-rRNA process; Tn mutation affects filamentous growth; macrophage/pseudohyphal-induced; physically interacts with TAP-tagged Nop1; Spider biofilm repressed || 1 -0.44 -0.57 -1.45 -1.42 -0.12 0.20 0.36 0.82 -0.75 0.84 0.73 -0.23 -0.08 0.45 -0.45 0.04
13070 || orf19.5783 || || || Ortholog(s) have protein-arginine omega-N monomethyltransferase activity and role in peptidyl-arginine methylation || 1 -0.36 -0.34 -1.05 -0.63 0.14 -0.20 -0.00 0.50 -0.53 0.63 0.48 -0.17 -0.08 0.13 -0.05 -0.07
13071 || orf19.1164 || GAR1 || || Putative H/ACA snoRNP pseudouridylase complex protein; mutation confers hypersensitivity to tubercidin (7-deazaadenosine); macrophage/pseudohyphal-induced; Spider biofilm repressed || 1 -0.26 -0.22 -0.96 -0.74 0.06 -0.23 0.38 0.93 -0.34 0.59 0.45 -0.05 -0.37 0.13 -0.44 0.27
13072 || orf19.3138 || NOP1 || || Nucleolar protein; flucytosine induced; Hap43-induced; Spider biofilm repressed || 1 -0.08 -0.16 -0.85 -0.62 0.05 0.11 0.30 0.94 -0.38 0.93 0.39 -0.17 -0.37 0.07 -0.29 0.46
13073 || orf19.3138 || NOP1 || || Nucleolar protein; flucytosine induced; Hap43-induced; Spider biofilm repressed || 1 -0.19 -0.22 -0.94 -0.64 -0.06 -0.06 0.06 0.84 -0.19 1.16 0.73 0.01 -0.24 0.12 -0.57 0.31
13074 || orf19.526 || NHP2 || || Putative H/ACA snoRNP protein; macrophage/pseudohyphal-induced || 1 -0.47 -0.48 -1.28 -1.04 -0.25 -0.34 0.41 0.99 -0.51 0.77 0.95 -0.00 -0.50 -0.04 -1.04 -0.14
13075 || orf19.526 || NHP2 || || Putative H/ACA snoRNP protein; macrophage/pseudohyphal-induced || 1 -0.27 -0.48 -1.50 -1.02 -0.35 -0.66 0.48 1.31 -0.61 0.50 1.04 -0.19 -0.63 -0.35 -0.77 -0.04
13076 || orf19.3291 || HMT1 || || Major type I protein arginine methyltransferase (PRMT); involved in asymmetric dimethylation of arginine residues; involved in nuclear export of Npl3p; Spider biofilm repressed || 1 -0.21 -0.25 -1.41 -0.80 -0.15 -0.68 0.13 0.76 -0.70 0.64 0.73 -0.44 -0.69 0.04 -0.91 0.32
13077 || orf19.7569 || SIK1 || || Putative U3 snoRNP protein; Hap43p-induced gene; physically interacts with TAP-tagged Nop1p || 1 -0.32 -0.21 -1.35 -0.97 0.06 -0.30 0.10 0.50 -0.18 0.74 0.39 -0.31 -0.55 0.36 -0.60 0.03
13078 || orf19.7569 || SIK1 || || Putative U3 snoRNP protein; Hap43p-induced gene; physically interacts with TAP-tagged Nop1p || 1 -0.74 -0.77 -1.88 -1.63 -0.24 -0.54 0.31 0.78 -0.76 0.49 0.55 -0.41 -1.09 0.17 -0.67 0.06
13079 || orf19.6090 || || || Putative nucleolar protein with a predicted role in pre-rRNA processing and ribosome biogenesis; repressed by nitric oxide; required for flow model biofilm formation; Spider biofilm repressed || 1 -0.35 -0.40 -1.67 -1.46 0.16 -0.42 0.40 0.78 -0.50 0.54 0.55 -0.41 -0.77 -0.04 -0.77 0.27
13080 || orf19.6090 || || || Putative nucleolar protein with a predicted role in pre-rRNA processing and ribosome biogenesis; repressed by nitric oxide; required for flow model biofilm formation; Spider biofilm repressed || 1 -0.43 -0.51 -1.93 -1.71 0.02 -0.37 0.54 0.79 -0.68 0.73 0.47 -0.30 -0.93 -0.22 -1.00 0.53
13081 || orf19.1164 || GAR1 || || Putative H/ACA snoRNP pseudouridylase complex protein; mutation confers hypersensitivity to tubercidin (7-deazaadenosine); macrophage/pseudohyphal-induced; Spider biofilm repressed || 1 -0.57 -0.57 -1.14 -0.75 -0.11 -0.34 0.17 0.79 -0.37 0.41 0.33 -0.23 -0.80 0.03 -0.83 -0.14
13082 || orf19.1402 || CCT2 || || Chaperonin of the cytosolic TCP1 ring complex; protein present in exponential and stationary-phase yeast cells, but higher amounts in stationary phase; GlcNAc-induced protein || 1 -0.57 -0.58 -1.15 -1.03 0.10 -0.56 0.03 0.60 -0.64 0.41 0.65 -0.05 -0.60 0.04 -0.25 0.08
13083 || orf19.518 || || || Ortholog(s) have tRNA (cytosine-5-)-methyltransferase activity, role in tRNA methylation and nucleus localization || 1 -0.33 -0.28 -1.17 -1.13 0.20 -0.16 -0.08 0.46 -0.67 0.60 0.28 -0.18 -0.51 0.10 -0.16 0.20
13084 || orf19.2720 || || || Cytosolic chaperonin Cct ring complex subunit; role in the assembly of actin and tubulins; Spider biofilm repressed || 1 -0.42 -0.58 -1.08 -0.93 0.27 -0.29 -0.16 0.16 -0.73 0.42 0.14 -0.14 -0.69 0.07 0.01 -0.03
13085 || orf19.4004 || CCT3 || || Putative cytosolic chaperonin Cct ring complex subunit; mutation confers hypersensitivity to cytochalasin D || 1 -0.34 -0.31 -1.30 -1.10 0.55 -0.07 0.13 0.65 -0.54 0.65 0.54 0.05 -0.39 0.35 0.48 -0.17
13086 || orf19.3129 || || || Putative chromatin remodelling complex protein; heterozygous null mutant displays sensitivity to virgineone; Spider biofilm repressed || 1 0.16 0.09 -0.50 -0.48 0.04 -0.22 0.01 0.47 -0.54 0.28 0.51 0.10 -0.07 0.34 0.06 0.13
13087 || orf19.6340 || || || Ortholog(s) have RNA polymerase I activity, RNA polymerase II activity, RNA polymerase III activity, RNA-directed RNA polymerase activity || 1 -0.01 0.12 -0.86 -1.09 0.15 0.09 -0.10 0.37 -0.98 0.41 0.77 -0.38 0.22 0.37 -0.11 0.24
13088 || orf19.3288 || NMA111 || || Putative serine protease and general molecular chaperone; macrophage-induced gene; repressed in core stress response; merged with orf19.3288.1 in Assembly 21 || 1 0.34 0.10 -0.93 -0.83 0.01 -0.01 -0.19 0.56 -0.27 0.68 0.70 -0.35 -0.07 0.07 -0.12 0.45
13089 || orf19.2406 || || || Ortholog(s) have role in microautophagy, positive regulation of TOR signaling cascade, positive regulation of transcription from RNA polymerase II promoter || 1 0.00 0.08 -0.68 -0.49 -0.01 -0.13 0.16 0.37 -0.28 0.09 0.44 -0.07 0.15 -0.07 -0.05 0.11
13090 || orf19.6563.1 || || || Ortholog(s) have role in mitochondrial respiratory chain complex IV assembly, negative regulation of mitochondrial translation and integral to mitochondrial inner membrane localization || 1 0.03 0.04 -1.04 -1.16 0.19 -0.43 0.51 0.86 0.10 0.21 0.45 -0.04 -0.33 0.03 0.15 -0.49
13091 || orf19.2378 || || || Ortholog(s) have role in syncytium formation by plasma membrane fusion, vacuolar proton-transporting V-type ATPase complex assembly and integral to endoplasmic reticulum membrane localization || 1 0.32 0.18 -0.70 -0.68 0.37 -0.24 0.34 0.58 -0.11 0.29 0.51 0.04 0.02 0.30 -0.07 -0.55
13092 || orf19.7182 || || || Ortholog(s) have RNA binding activity, role in tRNA modification and cytoplasm, nucleus localization || 1 0.35 0.35 -0.76 -0.68 0.56 0.16 0.29 0.63 -0.38 0.32 0.55 -0.31 -0.50 0.38 -0.35 -0.26
13093 || orf19.158 || || || Ortholog of S. cerevisiae Apd1; required for normal localization of actin patches and normal tolerance of sodium ions and hydrogen peroxide; Hap43-induced; Spider biofilm induced || 1 -0.27 -0.26 -1.09 -0.56 -0.43 0.09 0.38 0.55 -0.32 0.23 0.25 -0.46 0.22 0.61 0.10 0.04
13094 || orf19.5762 || PGA61 || || Putative GPI-anchored protein || 1 -0.60 -0.47 -0.55 -0.42 0.19 -0.17 -0.16 0.19 0.06 0.13 -0.06 -0.34 0.06 -0.01 -0.34 0.09
13095 || orf19.3312 || || || Protein of unknown function; flow model and Spider biofilm repressed || 1 -0.90 -1.04 -1.22 -1.37 1.25 0.23 -0.06 0.44 0.47 0.22 0.34 -0.14 -0.21 -0.06 -0.10 0.10
13096 || orf19.2105 || || || Putative pre-mRNA-splicing factor; possibly an essential gene, disruptants not obtained by UAU1 method || 1 -1.14 -1.23 -0.57 -0.64 0.43 0.42 -0.11 0.01 0.31 -0.02 0.37 0.51 -0.37 0.25 -0.40 0.14
13097 || orf19.1310 || || || Ortholog(s) have role in nucleotide-excision repair and nucleus localization || 1 -0.77 -1.11 -0.58 -0.51 0.47 0.21 -0.22 -0.25 0.31 0.15 -0.17 0.08 -0.53 0.02 -0.23 0.40
13098 || orf19.1310 || || || Ortholog(s) have role in nucleotide-excision repair and nucleus localization || 1 -0.26 -0.36 -0.31 -0.52 0.40 0.14 -0.06 0.22 0.16 0.28 0.11 0.16 -0.40 -0.02 0.38 0.41
13099 || orf19.264 || || || Has domain(s) with predicted protein kinase binding activity and role in regulation of cyclin-dependent protein serine/threonine kinase activity || 1 -0.20 -0.66 -1.30 -1.10 0.62 0.78 -0.31 0.39 0.03 0.58 0.57 0.17 -0.14 0.61 0.88 0.55
13100 || orf19.3265 || TRM1 || || Putative N2,N2-dimethylguanine tRNA methyltransferase; induced upon adherence to polystyrene || 1 -0.77 -0.78 -0.72 -0.76 0.40 0.22 0.10 0.66 -0.17 1.34 0.86 0.09 -0.18 0.69 0.32 0.14
13101 || orf19.6342 || || || Ortholog of C. dubliniensis CD36 : Cd36_11980, C. parapsilosis CDC317 : CPAR2_201330, Candida tenuis NRRL Y-1498 : CANTEDRAFT_114815 and Debaryomyces hansenii CBS767 : DEHA2G10032g || 1 -0.76 -1.17 -0.99 -0.59 0.65 0.17 0.07 0.29 0.03 0.58 0.25 0.32 -0.15 0.58 0.15 0.06
13102 || orf19.6233 || || || Ortholog(s) have endoplasmic reticulum, nuclear envelope localization || 1 -0.74 -0.84 -0.68 -0.54 0.25 0.73 0.22 0.15 -0.17 0.60 0.23 0.22 -0.19 0.45 0.62 0.47
13103 || orf19.7349 || CHS4 || || Activator of Chs3p chitin synthase; required for wild-type wall chitin content, but not for hyphal growth; mutant resistant to Calcofluor white; prenylation and 2 transmembrane segments predicted; functional homolog of S. cerevisiae Chs4p || 1 -0.67 -0.65 -0.85 -0.52 0.24 0.35 -0.27 -0.21 -0.20 0.66 0.46 0.37 0.24 -0.04 0.47 0.20
13104 || orf19.7652 || CKA1 || || Putative alpha subunit (catalytic subunit) of protein kinase CK2; Cka1p and Cka2p have a common target with respect to fluconazole resistance; synthetically lethal with CKA2; flucytosine induced || 1 -0.34 -0.41 -0.32 -0.40 -0.00 0.12 -0.34 0.01 -0.28 0.47 0.22 0.24 -0.10 0.28 0.23 0.24
13105 || orf19.304 || || || Putative transporter similar to MDR proteins; fungal-specific; Spider biofilm induced || 1 -0.92 -0.66 -0.81 -0.82 0.32 0.51 -0.10 0.07 0.01 0.97 0.83 0.34 -0.86 -0.31 0.71 0.21
13106 || orf19.5931 || ARV1 || || Lipid transporter involved in sterol trafficking and transport of glycosylphosphatidylinositol and sphingolipid precursors || 1 -0.75 -0.45 -0.49 -0.51 0.22 0.10 0.21 0.21 0.62 0.33 0.24 0.27 -0.17 0.08 0.57 -0.09
13107 || orf19.336 || YAH1 || || Protein similar to oxidoreductases; induced in high iron; Hap43-repressed || 1 -0.88 -0.88 -1.25 -0.93 0.97 0.26 0.73 0.49 0.27 0.79 0.72 0.40 -0.24 -0.19 0.93 -0.07
13108 || orf19.2363 || || || Ortholog(s) have thiosulfate sulfurtransferase activity and mitochondrion localization || 1 -0.41 -0.32 -0.63 -0.43 0.03 0.33 0.38 0.51 0.15 0.44 -0.03 0.38 -0.11 -0.05 0.53 0.23
13109 || orf19.6460 || PEX1 || || Ortholog(s) have ATPase activity, protein heterodimerization activity, role in fatty acid metabolic process, protein import into peroxisome matrix, receptor recycling and cytosol, peroxisomal membrane localization || 1 -0.70 -0.63 -0.75 -0.03 -0.17 0.20 0.16 0.39 0.37 0.63 -0.12 0.70 -0.27 0.27 0.36 0.54
13110 || orf19.3283 || || || Ortholog(s) have 3-oxoacyl-[acyl-carrier-protein] reductase (NADPH) activity, role in aerobic respiration, fatty acid metabolic process and mitochondrion localization || 1 -0.70 -0.51 -0.24 -0.40 -0.12 0.09 0.22 0.00 0.78 0.68 0.27 0.66 -0.11 0.25 0.21 0.26
13111 || orf19.6377 || || || Ortholog(s) have protein C-terminal leucine carboxyl O-methyltransferase activity, role in C-terminal protein methylation, cellular protein complex assembly and mitochondrion localization || 1 -0.60 -0.76 -0.40 -0.19 0.10 0.53 0.48 0.50 0.61 0.64 0.21 0.49 0.32 0.34 0.37 0.07
13112 || orf19.4467 || || || Ortholog of C. dubliniensis CD36 : Cd36_03660, C. parapsilosis CDC317 : CPAR2_106860, Candida tenuis NRRL Y-1498 : CANTEDRAFT_96694 and Debaryomyces hansenii CBS767 : DEHA2G15950g || 1 -0.62 -0.86 -0.44 -0.70 -0.31 -0.02 0.10 0.40 0.57 0.33 0.05 0.42 -0.66 -0.21 0.39 0.03
13113 || orf19.4897 || SFH5 || || Putative phosphatidylinositol transporter; rat catheter and Spider biofilm repressed || 1 -0.06 0.02 -0.54 -0.10 -0.29 -0.01 0.10 0.17 -0.12 0.09 0.36 0.22 -0.72 0.64 -0.08 0.66
13114 || orf19.7176 || NPT1 || || Putative nicotinate phosphoribosyltransferase, involved in NAD salvage pathway; fungal-specific (no human or murine homolog) || 1 -0.31 -0.35 -0.39 -0.31 -0.46 -0.28 -0.22 -0.12 -0.40 -0.02 0.64 0.41 -0.64 0.34 -0.04 0.93
13115 || orf19.5090 || || || Ortholog(s) have tRNA-specific adenosine deaminase activity, tRNA-specific adenosine-34 deaminase activity and role in adenosine to inosine editing, tRNA modification || 1 -0.33 -0.35 -0.65 -0.32 -0.28 -0.48 -0.57 0.10 -0.55 0.15 0.82 0.68 -0.75 0.24 0.05 0.96
13116 || orf19.5440 || RPT2 || || Putative ATPase of the 19S regulatory particle of the 26S proteasome; oxidative stress-induced via Cap1; Spider biofilm repressed || 1 -0.09 -0.03 -0.34 -0.40 -0.08 -0.34 0.15 0.09 -0.29 -0.02 0.29 0.38 -0.55 0.25 0.41 0.42
13117 || orf19.6076 || || || Ortholog(s) have protein transporter activity and role in ascospore formation, cellular response to cadmium ion, detoxification of cadmium ion, intracellular protein transport, retrograde transport, endosome to Golgi || 1 -0.58 -0.31 -0.50 -0.49 -0.14 -0.12 0.01 0.22 -0.16 0.05 0.45 0.56 -0.84 0.59 0.21 0.90
13118 || orf19.6076 || || || Ortholog(s) have protein transporter activity and role in ascospore formation, cellular response to cadmium ion, detoxification of cadmium ion, intracellular protein transport, retrograde transport, endosome to Golgi || 1 -0.48 -0.29 -0.95 -0.41 -0.15 0.05 0.00 0.49 -0.14 0.03 0.62 0.66 -0.42 0.33 0.54 0.91
13119 || orf19.7264 || || || Metalloprotease subunit of the 19S regulatory particle of the 26S proteasome lid; couples the deubiquitination and degradation of proteasome substrates; role in fission of mitochondria and peroxisome; Spider biofilm repressed || 1 -0.04 -0.24 -0.47 -0.28 0.01 0.09 0.02 0.11 0.02 0.23 0.46 0.53 -0.61 0.42 0.50 0.51
13120 || orf19.7264 || || || Metalloprotease subunit of the 19S regulatory particle of the 26S proteasome lid; couples the deubiquitination and degradation of proteasome substrates; role in fission of mitochondria and peroxisome; Spider biofilm repressed || 1 -0.10 -0.16 -0.28 -0.34 -0.14 -0.02 0.01 0.15 0.10 0.31 0.43 0.43 -0.48 0.35 0.53 0.62
13121 || orf19.3582 || || || Ortholog(s) have protein-lysine N-methyltransferase activity, role in peptidyl-lysine dimethylation, vesicle-mediated transport and cytosol, nucleus localization || 1 0.03 -0.35 -0.76 -0.23 -0.11 -0.28 -0.45 0.33 -0.84 0.76 0.84 0.92 -0.80 0.19 0.24 0.26
13122 || orf19.350 || PRE9 || || Alpha3 (C9) subunit of the 20S proteasome; transcript regulated by Mig1; flow model biofilm repressed || 1 0.15 0.15 -0.04 0.10 -0.49 -0.51 -0.15 0.15 -0.19 0.32 0.43 0.63 -0.14 -0.06 0.44 0.14
13123 || orf19.4102 || RPN10 || || Putative 19S regulatory particle of the 26S proteasome; macrophage/pseudohyphal-repressed; regulated by Gcn2 and Gcn4; Spider biofilm repressed || 1 -0.07 -0.18 -0.10 -0.15 -0.24 -0.36 -0.05 -0.01 -0.28 0.31 0.06 0.26 -0.37 -0.16 0.82 0.36
13124 || orf19.7286 || RPN7 || || Subunit of the proteasome regulatory particle; regulated by Gcn2p and Gcn4p; protein present in exponential and stationary growth phase yeast cultures || 1 0.08 -0.16 -0.34 -0.09 -0.28 -0.25 -0.11 0.01 -0.55 0.07 0.21 0.18 -0.59 -0.17 0.46 0.29
13125 || orf19.4993 || SEC18 || || Functional homolog of S. cerevisiae Sec18p, which acts in protein transport; conserved ATP binding site; not glycosylated || 1 0.01 0.06 -0.06 -0.02 -0.13 -0.11 0.03 -0.01 -0.30 0.33 0.38 0.38 -0.42 -0.11 0.52 0.48
13126 || orf19.6039 || || || Ortholog(s) have SNAP receptor activity and role in ER to Golgi vesicle-mediated transport, Golgi organization, intra-Golgi vesicle-mediated transport, vesicle fusion with Golgi apparatus || 1 0.00 0.04 -0.53 -0.22 -0.20 -0.03 -0.30 -0.07 -0.50 0.38 0.65 0.39 -0.43 -0.31 0.77 0.38
13127 || orf19.5046 || RAM1 || || Protein that acts in prenylation; transcription is alpha-factor induced; regulated in response to lovastatin and fluconazole; Hap43p-repressed gene || 1 0.20 0.06 -0.50 -0.04 -0.39 -0.26 -0.00 0.27 -0.23 0.23 0.75 0.56 -0.27 -0.25 0.60 0.21
13128 || orf19.4032 || RPN5 || || Putative COP9 signalosome component; macrophage/pseudohyphal-repressed || 1 0.04 -0.09 -0.23 -0.20 -0.30 -0.42 -0.02 0.12 -0.15 0.15 0.47 0.43 -0.42 -0.06 0.35 0.47
13129 || orf19.3054 || RPN3 || || Putative non-ATPase regulatory subunit of the 26S proteasome lid; amphotericin B repressed; oxidative stress-induced via Cap1p || 1 0.30 -0.13 -0.32 -0.33 -0.54 -0.49 0.39 0.24 -0.23 -0.05 0.81 0.25 -0.54 -0.17 0.44 0.64
13130 || orf19.5213 || || || Putative protein of unknown function; transcript is upregulated in clinical isolates from HIV+ patients with oral candidiasis || 1 0.12 0.01 -0.33 -0.64 0.09 0.06 0.34 0.22 -0.12 -0.19 0.71 0.22 0.06 -0.12 0.68 -0.07
13131 || orf19.5406 || || || Predicted plasma membrane associated protein phosphatase; required for normal filamentous growth; mRNA binds She3 and is localized to hyphal tips || 1 -0.09 -0.10 -0.62 -0.54 -0.00 -0.12 -0.16 -0.09 -0.39 -0.33 1.25 0.82 0.50 -0.33 0.31 0.34
13132 || orf19.2682 || || || Ortholog(s) have TBP-class protein binding, TBP-class protein binding RNA polymerase II transcription factor activity involved in preinitiation complex assembly activity || 1 0.05 0.05 -0.71 -0.60 -0.05 0.04 -0.05 -0.04 -0.38 -0.27 1.00 0.90 -0.10 -0.19 0.72 0.32
13133 || orf19.2682 || || || Ortholog(s) have TBP-class protein binding, TBP-class protein binding RNA polymerase II transcription factor activity involved in preinitiation complex assembly activity || 1 0.12 -0.02 -0.78 -0.90 0.03 0.01 -0.21 -0.16 -0.64 -0.47 0.91 0.51 -0.14 -0.41 0.61 -0.01
13134 || orf19.6602 || || || Ortholog(s) have role in aerobic respiration, ubiquinone biosynthetic process and mitochondrial inner membrane localization || 1 0.28 0.19 -0.68 -0.92 -0.51 -0.16 -0.42 0.31 -0.69 -0.38 0.81 0.31 -0.18 -0.46 0.56 0.41
13135 || orf19.121 || ARC18 || || Putative ARP2/3 complex subunit; mutation confers hypersensitivity to cytochalasin D || 1 0.16 0.06 -0.54 -0.71 0.35 -0.19 0.01 0.22 -0.37 -0.16 0.93 0.53 -0.55 0.24 0.53 0.29
13136 || orf19.4533 || || || Ortholog(s) have ribosome localization || 1 -0.10 -0.25 -0.50 -0.46 0.43 0.11 0.09 0.07 -0.11 0.08 0.49 0.47 -0.60 -0.53 0.54 0.54
13137 || orf19.4533 || || || Ortholog(s) have ribosome localization || 1 -0.16 -0.35 -0.71 -0.55 0.48 0.34 0.23 0.61 0.20 0.03 0.46 0.82 -0.24 -0.29 1.04 0.73
13138 || orf19.1085 || || || Ortholog(s) have ubiquitin-protein ligase activity || 1 -0.26 -0.48 -0.43 -0.09 0.23 0.11 0.25 0.70 -0.21 -0.04 0.53 0.50 0.21 -0.05 0.56 0.58
13139 || orf19.5074 || UBA2 || || Ortholog(s) have SUMO activating enzyme activity, role in protein sumoylation and SUMO activating enzyme complex localization || 1 -0.28 -0.64 -1.01 -0.85 0.09 -0.16 -0.31 0.06 -0.08 0.26 0.67 0.81 -0.06 0.17 0.42 0.74
13140 || orf19.757 || || || Ortholog of S. cerevisiae : YPR089W, C. glabrata CBS138 : CAGL0K08008g, C. dubliniensis CD36 : Cd36_04600, C. parapsilosis CDC317 : CPAR2_105630 and Candida tenuis NRRL Y-1498 : CANTEDRAFT_129373 || 1 -0.05 -0.07 -0.54 -0.54 0.41 -0.05 0.04 0.03 0.02 0.11 0.50 0.68 -0.23 0.14 0.43 0.57
13141 || orf19.5065 || ERD1 || || Putative membrane protein required for the retention of lumenal endoplasmic reticulum proteins; rat catheter biofilm induced || 1 0.10 -0.38 -0.48 -0.90 0.15 -0.38 0.13 0.25 0.08 -0.12 0.83 1.13 0.16 0.13 0.43 0.84
13142 || orf19.1716 || URA3 || || Orotidine-5'-phosphate decarboxylase; pyrimidine biosynthesis; gene used as genetic marker; decreased expression when integrated at ectopic chromosomal locations can cause defects in hyphal growth and virulence; Spider biofilm repressed || 1 -0.47 -0.21 -0.47 -0.59 0.07 0.25 0.44 0.28 -0.07 0.50 1.07 0.80 -0.01 -0.24 0.12 0.81
13143 || orf19.3836 || || || Ortholog(s) have cytoplasm localization || 1 -0.52 -0.31 -1.38 -1.11 0.45 0.36 0.32 0.49 -0.35 0.62 1.86 1.12 -1.02 -0.57 0.17 0.80
13144 || orf19.1917 || || || Protein of unknown function; Spider biofilm repressed || 1 -0.41 -0.20 -0.46 -0.35 0.16 -0.29 0.09 0.32 -0.11 0.25 0.99 0.54 -0.29 -0.19 0.06 0.47
13145 || orf19.4005 || || || Putative dephospho-CoA kinase; protein likely to be essential for growth, based on an insertional mutagenesis strategy || 1 -0.11 -0.27 -0.63 -0.56 0.33 -0.25 0.27 0.23 0.09 -0.32 0.90 0.67 -0.27 -0.21 0.34 0.29
13146 || orf19.1544 || || || Putative cis-golgi localized protein involved in ER to Golgi transport; Spider biofilm repressed || 1 -0.20 -0.35 -0.29 -0.78 0.30 0.01 0.14 0.51 -0.27 -0.10 1.28 0.73 0.00 0.04 0.33 0.28
13147 || orf19.326 || || || Protein of unknown function; Spider biofilm repressed || 1 -0.44 -0.41 -1.11 -0.74 0.24 -0.12 0.43 1.29 0.39 0.28 1.65 1.00 -0.66 0.07 0.61 0.37
13148 || orf19.326 || || || Protein of unknown function; Spider biofilm repressed || 1 -0.43 -0.36 -0.91 -0.65 0.09 0.20 0.60 0.88 0.15 0.04 1.76 0.97 -0.38 0.17 0.69 0.83
13149 || orf19.6135 || || || Ortholog of C. dubliniensis CD36 : Cd36_32970, C. parapsilosis CDC317 : CPAR2_701710, Candida tenuis NRRL Y-1498 : CANTEDRAFT_106599 and Debaryomyces hansenii CBS767 : DEHA2E04488g || 1 -0.11 -0.26 -0.49 -0.61 0.41 -0.04 0.29 0.45 0.02 -0.02 0.78 0.32 -0.16 0.31 0.41 0.31
13150 || orf19.6171 || NUP159 || || FG-nucleoporin component of central core of the nuclear pore complex (NPC); contributes to nucleocytoplasmic transport; rat catheter biofilm repressed || 1 -0.04 -0.27 -0.57 -0.58 0.40 0.15 0.28 0.54 -0.05 0.22 0.66 0.23 -0.27 0.22 0.57 0.49
13151 || orf19.1677 || || || Protein of unknown function; transcript detected on high-resolution tiling arrays || 1 -0.10 -0.21 -0.90 -0.45 0.61 -0.13 0.52 0.70 -0.10 0.11 0.92 1.04 0.34 0.05 0.73 0.76
13152 || orf19.6668 || || || Ortholog(s) have ubiquitin-protein ligase activator activity and role in ER-associated ubiquitin-dependent protein catabolic process, establishment of protein localization to endoplasmic reticulum membrane || 1 -0.14 -0.35 -0.56 -0.66 0.15 0.04 0.37 0.62 0.16 0.43 1.09 0.88 -0.06 -0.16 0.91 1.05
13153 || orf19.6668 || || || Ortholog(s) have ubiquitin-protein ligase activator activity and role in ER-associated ubiquitin-dependent protein catabolic process, establishment of protein localization to endoplasmic reticulum membrane || 1 -0.26 -0.17 -0.60 -0.74 0.19 -0.03 0.27 0.95 -0.03 0.14 1.32 0.90 -0.04 -0.14 1.07 1.12
13154 || orf19.2582 || || || Ortholog(s) have role in cytoplasmic translation, ribosome-associated ubiquitin-dependent protein catabolic process and RQC complex, cytosol, cytosolic large ribosomal subunit localization || 1 -0.42 -0.24 -0.83 -1.04 0.20 -0.02 0.33 0.38 -0.02 0.00 1.07 0.85 0.14 -0.06 1.25 0.64
13155 || orf19.5857 || || || Ortholog of C. dubliniensis CD36 : Cd36_84070, C. parapsilosis CDC317 : CPAR2_102720, Candida tenuis NRRL Y-1498 : CANTEDRAFT_98617 and Debaryomyces hansenii CBS767 : DEHA2D07392g || 1 -0.08 0.01 -0.24 -0.19 0.27 -0.02 0.28 0.41 -0.19 -0.07 0.95 0.51 -0.19 -0.22 0.77 0.58
13156 || orf19.6883 || || || Putative oxysterol binding protein family; probable peripheral membrane protein of the Golgi complex; flow model and Spider biofilm repressed || 1 0.12 -0.20 -0.75 -0.79 0.06 -0.09 0.32 0.32 -0.28 0.28 0.74 0.38 -0.27 0.12 0.99 0.70
13157 || orf19.886 || PAN1 || || Essential protein involved in endocytosis and polarized growth; ortholog of S. cerevisiae Pan1, which is a part of a complex that regulates actin cytoskeleton; Spider biofilm repressed || 1 -0.20 -0.32 -0.28 -0.28 -0.01 -0.14 0.30 0.27 0.16 0.10 0.32 0.25 0.01 0.01 0.41 0.20
13158 || orf19.6250 || || || Ortholog(s) have eukaryotic initiation factor 4G binding, mRNA binding activity || 1 -0.54 -0.62 -0.65 -0.51 -0.00 -0.10 0.73 0.47 0.02 -0.01 0.89 0.51 0.56 0.20 0.75 0.67
13159 || orf19.1837 || TBP1 || || Transcription initiation factor; binds TATA box sequence, binding does not require TFIIA; caspofungin repressed; functional homolog of S. cerevisiae and human TATA-binding proteins; Spider biofilm induced || 1 -0.39 -0.49 -0.45 -0.27 -0.40 -0.23 0.44 0.42 0.16 0.12 0.77 0.51 0.19 0.01 0.27 0.39
13160 || orf19.997 || SNL1 || || Ribosome-associated protein predicted to function in protein synthesis; 1 predicted transmembrane domain; rat catheter biofilm repressed || 1 -0.14 -0.10 -1.07 -0.75 -0.30 -0.79 0.31 0.82 -0.34 0.00 1.63 0.84 0.41 -0.00 1.02 0.33
13161 || orf19.4888 || || || Has domain(s) with predicted nucleic acid binding, nucleotide binding activity || 1 -0.39 -0.41 -0.82 -0.88 -0.33 -0.62 0.54 0.43 -0.25 0.28 1.21 0.85 0.38 0.45 1.02 0.44
13162 || orf19.1973 || HAP5 || || Component of CCAAT-binding transcription factor; roles in filamentous growth, low-iron induction of FRP1; regulates genes involved in respiratory growth; functional homolog of S. cerevisiae Hap5p; Cap1p-dependent expression in low iron || 1 -0.18 -0.23 -0.69 -0.38 -0.19 -0.17 0.27 0.31 -0.32 0.22 0.75 0.80 0.65 0.21 0.92 0.37
13163 || orf19.714 || || || Ortholog(s) have GTPase activity and role in intracellular protein transport, retrograde transport, endosome to Golgi || 1 -0.46 -0.18 -0.87 -0.50 -0.32 -0.32 0.82 0.52 -0.38 0.22 0.80 0.80 0.19 0.09 0.28 0.51
13164 || orf19.2499 || || || Putative peptidyl-prolyl cis-trans isomerase || 1 -0.20 0.00 -0.75 -0.58 0.25 0.22 0.47 0.14 -0.16 0.35 0.87 0.76 0.29 0.57 0.72 1.00
13165 || orf19.4637 || || || Ortholog(s) have role in SCF-dependent proteasomal ubiquitin-dependent protein catabolic process, cellular response to methylmercury and SCF ubiquitin ligase complex, cytosol localization || 1 -0.26 -0.27 -0.85 -1.57 0.02 0.34 0.71 0.62 0.15 -0.02 0.90 1.02 0.66 0.68 1.26 1.29
13166 || orf19.795 || VPS36 || || ESCRT II protein sorting complex subunit; involved in Rim8 processing and proteolytic activation of Rim101, which regulates pH response; role in uptake of Histatin-5 into vacuole || 1 -0.13 0.04 -0.69 -0.91 0.14 -0.13 0.09 0.16 0.20 -0.27 1.07 0.47 0.27 0.80 0.55 0.89
13167 || orf19.692 || || || Protein of unknown function; Hap43-repressed gene; rat catheter and Spider biofilm induced || 1 0.04 -0.26 -0.83 -0.80 0.19 -0.53 0.56 0.54 0.04 0.36 1.07 0.00 0.36 -0.45 1.28 1.17
13168 || orf19.1658 || || || Ortholog(s) have cell cortex, cellular bud neck, cellular bud tip, mating projection tip localization || 1 -0.38 -0.12 -0.99 -0.62 -0.01 -0.34 0.06 0.08 -0.13 0.05 0.65 0.06 0.56 0.06 1.10 0.53
13169 || orf19.932 || || || Putative aminophospholipid translocase (flippase); merged with orf19.2226 in Assembly 21; possibly an essential gene, disruptants not obtained by UAU1 method || 1 -0.42 -0.61 -0.81 -0.52 0.50 -0.04 0.24 -0.15 -0.39 -0.04 0.98 0.18 0.61 -0.30 0.95 0.60
13170 || orf19.1355 || || || Putative protein of unknown function; stationary phase enriched protein || 1 -0.34 -0.43 -0.64 -0.76 0.10 -0.30 0.15 0.12 -0.74 -0.03 0.88 -0.01 0.41 -0.32 0.88 0.23
13171 || orf19.1058 || || || Ortholog(s) have ubiquitin binding activity, role in ubiquitin-dependent protein catabolic process and proteasome regulatory particle, lid subcomplex, proteasome storage granule localization || 1 -0.20 -0.36 -0.80 -0.57 -0.11 -0.31 -0.14 0.54 -0.44 -0.17 0.58 0.42 -0.20 -0.29 0.47 0.27
13172 || orf19.3006 || GGA2 || || Protein involved in Golgi trafficking; rat catheter and Spider biofilm repressed || 1 -0.22 -0.32 -0.31 -0.21 -0.02 -0.24 -0.12 0.40 -0.17 -0.16 0.66 0.14 -0.19 -0.24 0.24 0.44
13173 || orf19.6328 || || || Putative protein of the mitochondrial intermembrane space; predicted role in acetate utilization and gluconeogenesis; Spider biofilm repressed || 1 -0.20 -0.06 -0.23 0.03 -0.03 0.01 0.23 0.70 -0.72 -0.20 1.39 0.63 -0.31 -0.42 0.41 0.49
13174 || orf19.6328 || || || Putative protein of the mitochondrial intermembrane space; predicted role in acetate utilization and gluconeogenesis; Spider biofilm repressed || 1 -0.04 0.01 -0.70 0.22 0.18 0.14 0.39 1.06 -0.11 0.63 1.90 1.01 -0.28 -0.54 0.78 0.26
13175 || orf19.5196 || ESS1 || || Prolyl isomerase (parvulin class); essential; involved in yeast-hyphal switching, Cph1p pathway; has inflexible linker between WW and isomerase domains, unlike human homolog; functional homolog of S. cerevisiae Ess1p || 1 0.05 0.32 -1.03 -0.23 -0.25 -0.04 0.79 1.03 -0.26 -0.12 1.37 0.65 0.31 -0.28 0.62 0.52
13176 || orf19.2297 || ARL3 || || Putative Ras superfamily GTPase; induced by nitric oxide independent of Yhb1p || 1 0.03 0.09 -0.20 -0.21 0.34 0.16 -0.23 0.35 -0.28 -0.09 0.48 0.39 0.31 -0.25 0.24 0.52
13177 || orf19.6636 || || || Protein of unknown function; rat catheter biofilm repressed || 1 0.04 -0.03 -0.35 -0.59 0.31 0.34 -0.04 -0.22 -0.06 0.22 0.84 0.57 0.37 -0.10 0.28 1.15
13178 || orf19.2119 || NDT80 || || Ortholog of Ndt80; meiosis-specific transcription factor; activator of CDR1 induction by antifungal drugs; required for wild-type drug resistance and for Spider biofilm formation; transcript induced by antifungal drug treatment || 1 -0.33 -0.20 -0.56 -0.91 -0.03 0.38 0.22 -0.23 -0.35 -0.26 1.46 0.82 0.53 0.02 0.45 1.23
13179 || orf19.557 || || || Protein of unknown function; Hap43-repressed; Spider biofilm repressed || 1 0.38 0.39 -0.81 -0.88 0.54 0.49 0.76 0.62 -0.66 -0.63 1.94 0.88 1.11 -0.01 0.44 1.47
13180 || orf19.2119 || NDT80 || || Ortholog of Ndt80; meiosis-specific transcription factor; activator of CDR1 induction by antifungal drugs; required for wild-type drug resistance and for Spider biofilm formation; transcript induced by antifungal drug treatment || 1 0.18 0.13 -0.42 -0.77 0.02 0.29 0.51 -0.39 -0.63 -0.29 1.61 0.56 1.20 -0.46 0.37 1.02
13181 || orf19.307 || || || Ortholog(s) have transcription coactivator activity, role in histone acetylation, transcription from RNA polymerase II promoter and Ada2/Gcn5/Ada3 transcription activator complex, SAGA complex, SLIK (SAGA-like) complex localization || 1 0.23 0.10 -0.09 -0.39 -0.05 -0.06 0.24 0.00 0.01 -0.12 0.49 0.36 0.44 -0.01 0.25 0.47
13182 || orf19.4683 || MLP1 || || Ortholog(s) have ribonucleoprotein complex binding activity || 1 0.14 -0.04 -0.20 -0.24 -0.08 0.00 0.15 0.15 -0.26 0.10 0.68 0.41 0.18 -0.25 0.43 0.44
13183 || orf19.1196 || PKH3 || || Ortholog(s) have protein kinase activity and role in MAPK cascade involved in cell wall biogenesis, protein phosphorylation || 1 -0.09 -0.02 -0.46 -0.36 -0.05 -0.34 0.06 0.23 -0.16 -0.35 0.38 0.43 0.19 -0.30 0.35 0.43
13184 || orf19.1275 || GAT1 || || GATA-type transcription factor; regulator of nitrogen utilization; required for nitrogen catabolite repression and utilization of isoleucine, tyrosine and tryptophan N sources; required for virulence in a mouse systemic infection model || 1 -0.61 0.01 -0.58 -0.48 0.25 -0.13 0.17 -0.08 0.06 -0.96 0.92 0.99 1.03 -0.53 1.00 1.58
13185 || orf19.835 || || || Ortholog(s) have role in nucleosome mobilization and Ino80 complex, cytosol localization || 1 0.06 0.01 -0.15 -0.10 0.08 0.09 0.06 0.10 0.06 -0.47 0.46 0.60 0.04 -0.44 0.11 0.73
13186 || orf19.7266 || || || Ortholog of Candida albicans WO-1 : CAWG_00007 || 1 -0.43 -0.38 -0.32 -0.10 0.13 0.42 0.49 0.34 0.18 -0.38 0.91 0.87 -0.09 -0.18 0.22 0.63
13187 || orf19.5145 || SSP96 || || Putative flavin-containing monooxygenase; F-12/CO2 early biofilm induced || 1 -0.21 -0.14 -0.27 -0.46 -0.85 -0.02 0.14 -0.16 0.09 -0.20 0.82 0.54 0.07 0.05 0.41 1.02
13188 || orf19.557 || || || Protein of unknown function; Hap43-repressed; Spider biofilm repressed || 1 -0.19 0.21 -1.26 -1.77 -1.93 -0.08 0.54 0.88 -0.44 -0.87 1.75 1.25 0.34 -0.08 0.14 1.60
13189 || orf19.5646 || || || Ortholog of S. cerevisiae : YPL034W, C. glabrata CBS138 : CAGL0L06996g, C. dubliniensis CD36 : Cd36_40280, C. parapsilosis CDC317 : CPAR2_402170 and Candida tenuis NRRL Y-1498 : CANTEDRAFT_137348 || 1 -0.19 -0.11 -1.24 -0.71 -1.55 -0.85 0.69 0.64 0.10 0.08 1.58 1.01 0.11 0.36 0.62 1.17
13190 || orf19.5046 || RAM1 || || Protein that acts in prenylation; transcription is alpha-factor induced; regulated in response to lovastatin and fluconazole; Hap43p-repressed gene || 1 0.21 0.27 -0.34 -0.05 -0.12 -0.16 -0.19 0.36 -0.08 0.26 0.74 0.92 -0.01 -0.17 0.39 0.64
13191 || orf19.2331 || ADA2 || || Zinc finger and homeodomain transcriptional coactivator; role in cell wall integrity and in sensitivity to caspofungin; required for the normal transcriptional response to caspofungin; required for yeast cell adherence to silicone substrate || 1 -0.16 -0.15 -0.13 -0.25 -0.04 -0.07 -0.13 -0.03 -0.06 0.39 0.36 0.79 0.13 -0.19 0.11 0.80
13192 || orf19.2473 || || || Putative RSC chromatin remodeling complex component; decreased transcription is observed upon fluphenazine treatment or in an azole-resistant strain that overexpresses CDR1 and CDR2 || 1 0.00 -0.30 0.07 -0.28 -0.21 -0.43 0.01 0.23 0.09 0.05 0.70 0.47 -0.03 0.43 0.40 0.58
13193 || orf19.4332 || || || Ortholog of C. dubliniensis CD36 : Cd36_52800, C. parapsilosis CDC317 : CPAR2_303110, Candida tenuis NRRL Y-1498 : CANTEDRAFT_92321 and Debaryomyces hansenii CBS767 : DEHA2G07964g || 1 -0.24 -0.39 -0.41 -0.72 -0.09 -0.59 0.40 0.26 0.73 -0.05 0.43 0.04 0.37 -0.18 0.51 0.20
13194 || orf19.1507 || AMN1 || || Putative negative regulator of exit from mitosis; Plc1-regulated; rat catheter biofilm induced || 1 0.03 0.12 -1.09 -0.73 0.50 0.20 0.57 0.37 0.32 0.15 0.55 0.08 1.04 0.54 -0.28 -0.04
13195 || orf19.3476 || HRR25 || || Predicted protein serine/threonine kinase; Spider biofilm induced || 1 -0.09 -0.04 -0.89 -0.77 0.01 -0.11 0.70 -0.08 0.04 -0.39 0.20 -0.00 1.26 0.33 0.37 0.19
13196 || orf19.5404 || || || Putative cell wall mannoprotein; repressed during the mating process; merged with orf19.5401 into orf19.5404.1; Spider biofilm induced || 1 -0.19 -0.15 -0.58 -0.68 0.19 0.12 0.49 0.37 0.13 -0.23 0.28 -0.20 0.80 0.40 -0.13 0.14
13197 || orf19.5402 || || || Ortholog of Candida albicans WO-1 : CAWG_02394 || 1 -0.31 -0.28 -0.58 -0.57 0.31 0.32 0.56 0.42 0.07 -0.13 0.17 -0.29 0.64 0.47 0.17 0.47
13198 || orf19.4928 || SEC2 || || Guanyl-nucleotide exchange factor for the small G-protein Sec4; delivery of post-Golgi secretory vesicles to sites of polarized growth; phosphorylation by Cdc28 needed for normal hyphal growth; Hap43-repressed; flow model biofilm induced || 1 -0.46 -0.46 -0.88 -1.08 0.47 -0.07 1.21 0.09 0.28 -0.19 0.18 0.04 0.45 0.47 -0.14 0.61
13199 || orf19.434 || PRD1 || || Putative proteinase; transcript regulated by Nrg1, Mig1, and Tup1; Hogp-induced; stationary phase enriched protein; Hap43-repressed; rat catheter biofilm repressed || 1 -0.79 -0.60 -1.09 -1.31 0.03 -0.66 1.31 1.15 0.66 -0.05 0.35 0.06 0.58 0.71 -0.00 -0.53
13200 || orf19.4280 || || || Protein of unknown function; Spider biofilm induced; rat catheter biofilm repressed || 1 -0.89 -0.85 -1.85 -1.87 0.46 -0.18 1.20 1.46 0.55 0.62 0.33 -0.72 1.44 0.64 0.07 -0.33
13201 || orf19.1546 || || || Membrane-localized protein of unknown function || 1 -0.64 -0.63 -1.39 -1.85 0.26 -0.35 1.09 0.84 0.63 0.04 0.04 -0.61 0.02 -0.09 0.49 -0.61
13202 || orf19.6829 || || || Protein with a predicted mitochondrial ATPase expression domain; possibly an essential gene, disruptants not obtained by UAU1 method || 1 -0.33 -0.38 -0.69 -0.42 -0.43 -0.26 0.67 0.31 0.81 0.81 0.07 -0.04 0.62 0.49 0.13 -0.15
13203 || orf19.3133 || GUT2 || || Glycerol-3-phosphate dehydrogenase; Plc1p-regulated; rat catheter biofilm induced; Spider biofilm induced || 1 -0.50 -0.46 -0.37 -0.08 -0.47 -0.46 0.34 0.15 0.34 0.44 0.12 -0.13 0.07 0.72 -0.24 -0.34
13204 || orf19.5762 || PGA61 || || Putative GPI-anchored protein || 1 -0.84 -0.85 -0.29 -0.65 -0.49 -1.15 0.72 1.17 0.47 0.07 -0.32 -0.18 0.38 1.02 -0.67 -0.50
13205 || orf19.4520 || || || Putative gluconokinase; rat catheter biofilm induced || 1 -0.51 -0.74 -0.40 -0.17 -0.81 -0.88 0.66 0.50 -0.30 0.30 -0.31 -0.58 0.68 1.09 -0.22 -0.05
13206 || orf19.5762 || PGA61 || || Putative GPI-anchored protein || 1 -0.29 -0.51 -0.55 -1.25 -0.17 -2.46 1.08 0.55 0.29 0.05 0.07 -0.02 0.79 1.32 0.14 -0.08
13207 || orf19.2494 || || || Ortholog(s) have glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity, role in glutaminyl-tRNAGln biosynthesis via transamidation, mitochondrial translation and glutamyl-tRNA(Gln) amidotransferase complex, mitochondrion localization || 1 -0.63 -0.51 -0.61 -0.46 -0.01 -0.57 0.26 0.14 0.45 0.26 0.25 0.09 0.67 0.55 0.04 -0.12
13208 || orf19.2494 || || || Ortholog(s) have glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity, role in glutaminyl-tRNAGln biosynthesis via transamidation, mitochondrial translation and glutamyl-tRNA(Gln) amidotransferase complex, mitochondrion localization || 1 -0.69 -0.73 -0.73 -0.89 -0.43 -0.64 0.10 -0.02 0.06 0.11 -0.20 -0.03 0.27 0.55 0.14 -0.46
13209 || orf19.1053 || || || Ortholog(s) have phosphatidylinositol deacylase activity || 1 -0.72 -0.82 -1.38 -1.55 -0.85 -1.21 0.38 0.38 0.04 0.25 0.22 -0.35 0.34 1.00 -0.45 -0.24
13210 || orf19.1767 || || || Ortholog(s) have protein complex scaffold, ubiquitin-specific protease activity, role in histone H3-K4 methylation, histone H3-K79 methylation, histone deubiquitination and DUBm complex, SAGA complex, SLIK (SAGA-like) complex localization || 1 -0.38 -0.44 -0.83 -0.94 -0.46 -0.68 0.27 0.23 0.27 0.49 -0.22 0.16 0.21 0.63 -0.07 -0.07
13211 || orf19.5271 || || || Protein of unknown function; Hap43-induced gene || 1 -0.69 -0.76 -0.59 -0.79 -0.79 -0.93 -0.06 0.35 0.12 0.55 -0.06 0.06 0.48 0.94 -0.15 0.16
13212 || orf19.4171 || || || Has domain(s) with predicted ATP binding activity || 1 -0.69 -0.61 -0.92 -0.82 -0.63 -0.61 0.64 0.96 0.47 0.35 0.20 0.14 -0.21 1.21 -0.01 0.31
13213 || orf19.4171 || || || Has domain(s) with predicted ATP binding activity || 1 -0.39 -0.46 -1.12 -1.04 -0.50 -0.96 0.69 0.66 0.18 0.07 0.15 -0.16 -0.04 1.03 -0.08 0.28
13214 || orf19.71 || || || Ortholog(s) have role in ER to Golgi vesicle-mediated transport, protein secretion and COPII vesicle coat, Golgi membrane, cell division site, cell tip, cis-Golgi network, cytosol, nucleus localization || 1 -0.14 -0.23 -0.43 -0.53 -0.04 -0.34 0.28 0.22 0.25 0.06 0.32 -0.07 0.02 0.59 0.13 0.06
13215 || orf19.4209 || || || Ortholog(s) have NEDD8 activating enzyme activity, role in protein neddylation and cytosol, nucleus localization || 1 -0.22 -0.16 -0.32 -0.24 -0.30 -0.36 0.12 0.19 -0.04 0.15 0.27 0.23 -0.01 0.64 0.09 0.10
13216 || orf19.1233 || ADE4 || || Putative phosphoribosylpyrophosphate amidotransferase; flucytosine induced || 1 0.11 0.12 -1.23 -0.80 -1.00 -1.22 0.37 0.66 0.09 0.77 0.34 0.03 0.29 0.87 -0.01 -0.13
13217 || orf19.4297 || CKB2 || || Regulatory subunit of protein kinase CK2 (casein kinase II), beta' subunit; null mutants are hypersensitive to caspofungin || 1 0.04 0.00 -0.43 -0.51 -0.30 -0.43 0.71 0.54 -0.01 0.44 0.10 -0.08 0.32 0.47 -0.04 0.00
13218 || orf19.4159 || || || Has domain(s) with predicted role in transmembrane transport || 1 -0.28 -0.13 -0.65 -1.11 -0.73 -0.72 0.12 0.60 0.59 1.04 0.34 0.29 0.31 0.65 0.27 0.22
13219 || orf19.6606 || || || Ortholog of C. parapsilosis CDC317 : CPAR2_201040, Candida tenuis NRRL Y-1498 : CANTEDRAFT_112677, Debaryomyces hansenii CBS767 : DEHA2E02420g and Pichia stipitis Pignal : PICST_37559 || 1 -0.25 -0.36 -0.79 -1.28 -1.33 -1.09 0.14 0.75 0.89 0.50 -0.17 0.58 0.61 0.79 0.91 0.43
13220 || orf19.4647 || HAP3 || || Predicted CCAAT-binding transcription factor that regulates respiration; Cap2-dependent induction in low iron; opaque specific, alkaline, ciclopirox olamine induced; regulated by Sef1, Sfu1, Hap43; Bcr1-regulated in RPMI a/a biofilms || 1 -0.87 -0.49 -1.43 -2.45 -0.25 -1.44 0.63 0.72 0.16 0.23 -0.15 -0.53 2.31 2.33 0.99 1.21
13221 || orf19.2007 || || || Ortholog(s) have role in Golgi to vacuole transport, ascospore wall assembly, retrograde transport, endosome to Golgi and GARP complex, mitochondrion localization || 1 -0.30 -0.32 -0.49 -0.54 -0.13 -0.55 0.14 0.21 0.36 -0.20 0.20 0.20 0.46 0.50 -0.11 0.41
13222 || orf19.6978 || || || Planktonic growth-induced gene || 1 -0.18 -0.28 -0.51 -1.10 -0.24 -0.49 0.66 0.59 0.38 -0.04 0.19 0.28 1.20 0.71 -0.27 0.06
13223 || orf19.1948 || || || Ortholog of C. dubliniensis CD36 : Cd36_51110, C. parapsilosis CDC317 : CPAR2_302560, Candida tenuis NRRL Y-1498 : CANTEDRAFT_135271 and Debaryomyces hansenii CBS767 : DEHA2E12914g || 1 -0.07 -0.07 -0.73 -0.47 -0.01 -0.33 0.55 0.39 0.27 0.03 0.43 -0.10 0.55 0.39 -0.51 -0.14
13224 || orf19.6342 || || || Ortholog of C. dubliniensis CD36 : Cd36_11980, C. parapsilosis CDC317 : CPAR2_201330, Candida tenuis NRRL Y-1498 : CANTEDRAFT_114815 and Debaryomyces hansenii CBS767 : DEHA2G10032g || 1 -0.32 0.22 -2.35 -0.62 -0.34 -1.56 0.93 0.79 0.51 0.58 0.89 0.44 0.72 0.44 -0.53 -0.25
13225 || orf19.7358 || SAM50 || || Predicted component of the SAM complex involved in mitochondrial protein import || 1 0.03 -0.53 -1.28 -0.12 -0.12 -0.41 0.69 0.30 0.35 0.52 0.44 0.52 0.54 0.50 0.04
13226 || orf19.1803 || CDC43 || || Beta subunit of heterodimeric protein geranylgeranyltransferase type I; GGTase I enzyme binds zinc, is Mg-dependent; Cdc42p is GGTase I substrate || 1 -0.24 -0.53 -0.79 -0.15 -0.14 -0.45 0.22 0.31 0.06 0.74 0.88 0.29 0.31 -0.03 -0.03 0.03
13227 || orf19.6036 || RIC1 || || Ortholog of S. cerevisiae Ric1 guanyl-nucleotide exchange factor; mutant is viable; rat catheter biofilm repressed || 1 -0.17 -0.48 -0.44 -0.37 -0.24 -0.67 0.16 0.25 0.16 -0.14 0.16 0.65 -0.18 0.43 -0.13 0.16
13228 || orf19.1343 || MED16 || || Putative RNA polymerase II mediator complex subunit; induced by nitric oxide || 1 -0.43 -0.29 -0.54 -0.62 -0.02 -0.45 0.09 0.19 0.17 -0.16 0.15 0.45 -0.02 0.34 0.13 0.05
13229 || orf19.1699 || BZZ1 || || Protein similar to S. cerevisiae Bzz1p, which is an SH3 domain protein involved in the regulation of actin polymerization || 1 -0.71 -0.18 -0.59 -1.12 -0.59 -0.71 0.17 -0.07 0.25 -0.03 0.23 0.62 0.12 0.40 0.51 0.69
13230 || orf19.1373 || INP51 || || Putative phosphatidylinositol-4,5-bisphosphate phosphatase; involved in maintenance of phosphoinositide levels; affects hyphal growth, virulence, cell integrity; interacts with Irs4p || 1 -0.67 -0.25 -0.37 -0.73 -0.17 -0.60 0.10 0.09 0.21 -0.21 0.33 0.59 -0.36 0.02 0.05 0.86
13231 || orf19.5966 || || || Ortholog of Candida albicans WO-1 : CAWG_02810 || 1 -0.36 -0.20 -1.51 -0.32 -0.26 -1.26 0.20 -0.04 0.21 0.35 0.65 0.41 -0.74 0.29 0.06 0.74
13232 || orf19.2975 || YPT7 || || Protein of YPT/RAB family; induced during the mating process || 1 -0.08 -0.29 -1.25 -0.52 -0.34 -0.46 0.58 0.79 -0.04 0.40 0.57 0.21 -0.28 0.02 0.28 0.52
13233 || orf19.71 || || || Ortholog(s) have role in ER to Golgi vesicle-mediated transport, protein secretion and COPII vesicle coat, Golgi membrane, cell division site, cell tip, cis-Golgi network, cytosol, nucleus localization || 1 -0.17 -0.34 -0.52 -0.43 -0.20 -0.28 0.43 0.48 0.16 -0.12 0.32 0.44 -0.18 0.15 0.36 0.33
13234 || orf19.7292 || ARP2 || || Component of the Arp2/3 complex; required for virulence, hyphal growth, cell wall/cytoskeleton organization, not for endocytosis; mutation confers hypersensitivity to cytochalasin D; regulated by Gcn2 and Gcn4; Spider biofilm repressed || 1 -0.35 -0.29 -0.42 -0.40 -0.32 -0.43 0.28 0.34 0.19 -0.05 0.42 0.23 -0.43 0.26 0.18 0.42
13235 || orf19.5793 || PR26 || || Protein with similarity to proteasomal 26S regulatory subunit of S. cerevisiae, H. sapiens, Methanobacterium thermoautotrophicum (Archaebacterium) || 1 -0.32 -0.25 -0.53 -0.50 -0.20 -0.63 0.17 0.23 0.12 0.18 0.34 0.28 -0.33 0.39 0.59 0.69
13236 || orf19.5440 || RPT2 || || Putative ATPase of the 19S regulatory particle of the 26S proteasome; oxidative stress-induced via Cap1; Spider biofilm repressed || 1 -0.11 -0.02 -0.32 -0.40 -0.15 -0.44 0.05 0.14 -0.09 0.48 0.51 0.41 -0.46 -0.05 0.20 0.27
13237 || orf19.588 || || || Ortholog(s) have role in aerobic respiration and mitochondrial intermembrane space, nucleus localization || 1 -0.47 -0.16 -1.17 -0.71 -0.72 -1.31 0.51 0.62 -0.16 0.96 0.94 0.76 -0.88 -0.44 0.02 0.54
13238 || orf19.1560 || POB3 || || Protein involved in chromatin assembly and disassembly; ortholog of S. cerevisiae Pob3; transposon mutation affects filamentous growth; rat catheter biofilm repressed || 1 -0.40 -0.42 -0.88 -0.68 -0.27 -0.86 0.14 0.67 -0.29 0.25 0.92 0.29 -0.73 0.13 -0.21 0.23
13239 || orf19.1560 || POB3 || || Protein involved in chromatin assembly and disassembly; ortholog of S. cerevisiae Pob3; transposon mutation affects filamentous growth; rat catheter biofilm repressed || 1 -0.49 -0.35 -0.71 -0.47 -0.38 -0.75 0.17 0.71 -0.28 0.37 0.93 0.32 -0.69 0.36 -0.11 0.55
13240 || orf19.5378 || SCL1 || || Proteasome subunit YC7alpha; protein present in exponential and stationary growth phase yeast cultures; flow model and Spider biofilm repressed || 1 -0.01 -0.14 -0.27 -0.45 -0.29 -0.78 0.22 0.50 -0.30 0.12 0.43 0.47 -0.64 0.22 0.19 0.48
13241 || orf19.544.1 || PRE6 || || Putative alpha-4 subunit of the proteasome; reported as macrophage-induced protein and macrophage/pseudohyphal-repressed gene; regulated by Gcn2p and Gcn4p; removed from/reinstated in Assembly 20 (see Locus History) || 1 0.01 -0.20 -0.40 -0.32 -0.60 -0.82 0.14 0.42 -0.13 0.28 0.64 0.20 -0.41 0.18 0.40 -0.19
13242 || orf19.4032 || RPN5 || || Putative COP9 signalosome component; macrophage/pseudohyphal-repressed || 1 -0.07 -0.17 -0.70 -0.62 -0.50 -0.91 0.00 0.22 -0.28 -0.08 0.47 0.22 -0.79 -0.09 0.25 0.17
13243 || orf19.3123 || RPT5 || || 26S proteasome regulatory subunit; transcript regulated by Nrg1 and Mig1; regulated by Gcn2 and Gcn4; protein level decreases in stationary phase || 1 -0.09 -0.16 -0.46 -0.50 -0.29 -0.65 -0.02 0.11 0.03 0.10 0.24 -0.01 -0.53 0.09 0.33 0.08
13244 || orf19.3123 || RPT5 || || 26S proteasome regulatory subunit; transcript regulated by Nrg1 and Mig1; regulated by Gcn2 and Gcn4; protein level decreases in stationary phase || 1 -0.14 -0.28 -0.71 -0.71 -0.32 -0.61 0.00 0.12 -0.08 0.09 0.41 0.30 -0.35 0.16 0.50 0.09
13245 || orf19.2755 || || || Ortholog(s) have role in proteasomal ubiquitin-independent protein catabolic process, proteasome-mediated ubiquitin-dependent protein catabolic process and cytosol, nucleus, proteasome core complex, beta-subunit complex localization || 1 -0.06 0.00 -0.61 -0.40 -0.40 -0.70 0.16 0.39 -0.23 0.17 0.55 0.31 -0.36 0.34 0.63 0.35
13246 || orf19.3531 || || || Ortholog(s) have role in regulation of DNA-dependent DNA replication initiation and DNA replication preinitiation complex, endoplasmic reticulum, nuclear envelope, spindle pole body localization || 1 -0.12 -0.20 -0.68 -0.49 -0.35 -0.58 -0.01 0.24 -0.44 0.00 0.53 0.17 0.01 0.51 0.40 0.12
13247 || orf19.6379 || || || Ortholog of C. dubliniensis CD36 : Cd36_33820, C. parapsilosis CDC317 : CPAR2_206210, Candida tenuis NRRL Y-1498 : CANTEDRAFT_92567 and Debaryomyces hansenii CBS767 : DEHA2E06138g || 1 -0.46 -0.41 -0.61 -0.54 -0.19 -0.50 -0.22 0.19 -0.14 -0.30 0.29 0.33 0.19 -0.39 0.37 -0.20
13248 || orf19.6096 || TRP1 || || Phosphoribosylanthranilate isomerase; tryptophan biosynthesis; expected unifunctional, unlike trifunctional enzyme of some other fungi; complements E. coli trpC, S. cerevisiae trp1 mutant; CCT1 and TRP1 overlap; Spider biofilm repressed || 1 -0.58 -0.62 -0.90 -0.56 -0.12 -0.44 0.12 0.21 -0.05 -0.05 0.26 0.49 -0.01 -0.27 0.30 -0.36
13249 || orf19.5107 || NOT5 || || Protein with similarity to S. cerevisiae Not5p, a member of the transcription regulatory CCR4-NOT complex; required for hyphal growth; antigenic during human oral infection; greater expression in yeast-form cells than hyphae || 1 -0.44 -0.44 -0.59 -0.75 -0.17 -0.52 0.04 -0.04 -0.30 0.22 0.35 0.47 0.29 -0.01 0.47 -0.09
13250 || orf19.1698 || || || Ortholog(s) have phosphatidate phosphatase activity, role in actin cytoskeleton organization, cellular lipid metabolic process and actin cortical patch localization || 1 -0.77 -0.72 -1.43 -1.13 0.18 -0.47 0.26 0.37 0.27 0.35 -0.10 0.10 0.10 0.39 0.50 -0.18
13251 || orf19.1767 || || || Ortholog(s) have protein complex scaffold, ubiquitin-specific protease activity, role in histone H3-K4 methylation, histone H3-K79 methylation, histone deubiquitination and DUBm complex, SAGA complex, SLIK (SAGA-like) complex localization || 1 -0.46 -0.41 -1.12 -1.12 -0.03 -0.04 0.43 0.03 0.17 0.36 -0.27 0.16 0.39 0.37 0.06 0.11
13252 || orf19.3141 || || || Ortholog(s) have role in ER to Golgi vesicle-mediated transport and cytoplasmic mRNA processing body, endoplasmic reticulum membrane, extrinsic to membrane localization || 1 -0.51 -0.63 -0.75 -0.88 -0.04 -0.11 0.15 0.17 -0.06 0.62 0.22 0.54 0.36 0.62 0.36 0.04
13253 || orf19.1219 || || || Ortholog of Spathaspora passalidarum NRRL Y-27907 : SPAPADRAFT_149713 || 1 -0.86 -0.57 -0.89 -0.54 0.06 -0.16 -0.10 0.21 0.00 0.49 0.54 0.55 -0.09 -0.12 0.35 -0.16
13254 || orf19.4426 || PEX3 || || Putative peroxisomal protein involved in targeting proteins into peroxisomes; possibly an essential gene, disruptants not obtained by UAU1 method || 1 -0.87 -0.55 -1.14 -0.98 -0.30 -0.34 -0.02 0.16 0.33 0.67 0.49 0.44 0.03 0.08 0.62 -0.49
13255 || orf19.425 || || || Has domain(s) with predicted translation release factor activity and role in translational termination || 1 -0.65 -0.75 -1.08 -0.89 -0.80 -0.88 -0.04 0.25 0.26 0.32 0.84 0.32 0.25 0.51 0.43 -0.49
13256 || orf19.7662 || || || Ortholog(s) have RNA polymerase II core binding activity, role in mRNA 3'-end processing, negative regulation of transposition, RNA-mediated and nuclear chromatin, site of double-strand break localization || 1 -0.90 -0.63 -0.96 -0.72 -0.75 -1.00 0.41 0.49 -0.07 -0.09 0.60 0.08 0.59 0.14 0.69 -0.15
13257 || orf19.1086 || || || Ortholog(s) have role in protein deubiquitination, regulation of ER to Golgi vesicle-mediated transport, regulation of retrograde vesicle-mediated transport, Golgi to ER, ribophagy and cytoplasm localization || 1 -0.50 -0.44 -1.01 -0.69 -0.20 -0.41 0.71 0.64 -0.23 0.24 0.64 0.14 0.31 -0.22 0.09 0.19
13258 || orf19.2259 || || || Ortholog(s) have structural constituent of ribosome activity and mitochondrial large ribosomal subunit localization || 1 -0.50 -0.12 -1.17 -1.29 -0.02 -0.80 0.42 1.10 0.23 0.64 1.37 0.73 0.23 -0.13 0.63 0.38
13259 || orf19.3367 || || || Ortholog(s) have structural constituent of ribosome activity and mitochondrial large ribosomal subunit localization || 1 -0.68 -0.35 -1.88 -1.49 0.26 -0.83 0.92 1.33 0.55 1.10 0.67 0.01 0.86 -0.17 0.92 -0.38
13260 || orf19.6136 || || || Ortholog of S. cerevisiae Mrpl4, a mitochondrial ribosomal protein of the large subunit; repressed by nitric oxide || 1 -0.50 -0.49 -1.16 -1.36 -0.03 -0.31 0.52 0.47 0.13 0.83 0.31 0.08 0.54 -0.16 0.72 -0.23
13261 || orf19.6853 || || || Protein of unknown function; Spider biofilm repressed || 1 -0.69 -0.63 -1.45 -1.60 0.22 -0.67 0.75 0.80 0.23 0.86 0.60 0.25 0.42 -0.04 0.63 -0.58
13262 || orf19.185 || || || Ortholog(s) have structural constituent of ribosome activity, role in mitochondrial translational initiation and mitochondrial small ribosomal subunit localization || 1 -0.23 -0.21 -0.86 -1.13 -0.04 -0.37 0.50 0.60 0.21 0.44 0.27 0.19 0.13 -0.12 0.41 -0.40
13263 || orf19.5161 || || || Ortholog(s) have structural constituent of ribosome activity and mitochondrial large ribosomal subunit localization || 1 -0.02 -0.21 -1.35 -1.45 -0.08 -0.89 0.84 1.15 -0.07 0.35 1.13 -0.16 0.20 -0.22 0.66 -0.10
13264 || orf19.688 || || || Mitochondrial ribosomal protein of the small subunit; S. cerevisiae ortholog is essential for viability; Spider biofilm repressed || 1 -0.23 -0.12 -1.48 -1.63 -0.11 -1.47 0.83 1.19 0.36 0.75 1.17 0.14 0.43 0.06 0.44 0.14
13265 || orf19.5515 || || || Ortholog(s) have ribosome binding activity, role in mitochondrial respiratory chain complex III assembly, positive regulation of mitochondrial translation and integral to mitochondrial membrane, mitochondrial ribosome localization || 1 -0.52 -0.45 -1.71 -1.76 0.07 -1.17 0.85 0.90 0.34 0.57 0.59 -0.04 -0.08 0.27 0.23 0.07
13266 || orf19.5515 || || || Ortholog(s) have ribosome binding activity, role in mitochondrial respiratory chain complex III assembly, positive regulation of mitochondrial translation and integral to mitochondrial membrane, mitochondrial ribosome localization || 1 -0.44 -0.49 -1.14 -1.29 -0.06 -0.74 0.56 0.59 0.45 0.38 0.36 0.22 -0.26 0.21 -0.04 -0.09
13267 || orf19.3559 || || || S. cerevisiae ortholog Mrps35p is a structural constituent of ribosome and localizes to mitochondrial small ribosomal subunit; the snoRNA CD39 is encoded within the MRPS35 intron || 1 -0.45 -1.06 -1.09 -1.59 -0.60 -0.89 0.60 1.03 0.38 0.86 0.54 0.53 0.14 0.16 0.54 -0.24
13268 || orf19.7617 || || || Ortholog(s) have peptide alpha-N-acetyltransferase activity, role in N-terminal protein amino acid acetylation, histone acetylation and NatA complex, cytosol, cytosolic ribosome, nucleus localization || 1 -0.63 -0.65 -1.26 -1.05 -0.65 -0.82 0.47 0.69 -0.12 0.83 0.73 0.72 -0.08 0.47 0.02 0.22
13269 || orf19.5143 || TIM54 || || Predicted component of the mitochondrial TIM22 complex; involved in protein import into mitochondrial inner membrane; Spider biofilm repressed || 1 -0.66 -0.64 -1.48 -1.51 -0.43 -1.14 0.29 0.89 -0.09 0.88 0.87 0.22 -0.18 0.07 0.11 0.17
13270 || orf19.7064 || GLN4 || || Putative tRNA-Gln synthetase; genes encoding ribosomal subunits, translation factors, tRNA synthetases are downregulated upon phagocytosis by murine macrophage; protein present in exponential and stationary growth phase yeast cultures || 1 -0.97 -1.01 -1.86 -1.50 -0.41 -1.18 0.49 1.23 -0.12 1.05 1.05 0.03 -0.04 0.38 0.34 0.44
13271 || orf19.6213 || SUI2 || || Translation initiation factor eIF2, alpha chain; genes encoding ribosomal subunits, translation factors, and tRNA synthetases are downregulated upon phagocytosis by murine macrophage; stationary phase enriched protein || 1 -0.79 -0.81 -2.28 -1.71 -0.17 -1.10 0.47 0.98 -0.13 0.79 1.33 0.36 -0.13 0.66 0.12 0.20
13272 || orf19.6213 || SUI2 || || Translation initiation factor eIF2, alpha chain; genes encoding ribosomal subunits, translation factors, and tRNA synthetases are downregulated upon phagocytosis by murine macrophage; stationary phase enriched protein || 1 -0.65 -0.61 -2.21 -1.54 -0.25 -1.05 0.68 1.22 -0.18 0.72 1.44 0.28 0.02 0.32 0.15 0.40
13273 || orf19.7236 || TIF35 || || Putative translation initiation factor; repressed upon phagocytosis by murine macrophage; Spider biofilm repressed || 1 -1.00 -1.14 -2.14 -1.44 -0.09 -0.90 0.59 1.22 -0.05 0.80 0.80 0.20 -0.36 0.54 0.17 -0.08
13274 || orf19.7064 || GLN4 || || Putative tRNA-Gln synthetase; genes encoding ribosomal subunits, translation factors, tRNA synthetases are downregulated upon phagocytosis by murine macrophage; protein present in exponential and stationary growth phase yeast cultures || 1 -0.77 -1.03 -1.65 -1.55 -0.07 -0.87 0.46 1.23 -0.08 1.11 1.11 0.35 0.15 0.69 -0.06 -0.10
13275 || orf19.4620 || TIM12 || || Predicted component of the TIM22 complex, involved in protein import into mitochondrial inner membrane; flow model biofilm induced || 1 -1.63 -1.11 -2.60 -2.49 -0.73 -1.29 1.35 1.82 0.23 0.68 1.90 0.59 0.17 0.66 0.08 0.35
13276 || orf19.2128 || || || Ortholog(s) have mitochondrion localization || 1 -0.96 -0.71 -1.35 -1.37 -0.34 -0.55 0.13 0.82 0.29 0.64 0.69 0.38 -0.11 0.49 0.37 0.27
13277 || orf19.1662 || || || Ortholog(s) have structural constituent of ribosome activity and mitochondrial small ribosomal subunit localization || 1 -0.95 -1.00 -1.69 -1.43 0.23 -0.77 0.74 0.88 0.07 1.02 0.58 0.67 0.78 0.05 0.73 0.16
13278 || orf19.5747 || || || Ortholog(s) have structural constituent of ribosome activity and mitochondrial small ribosomal subunit localization || 1 -0.58 -0.54 -1.59 -1.37 -0.35 -0.59 0.48 1.18 0.44 1.01 0.66 0.50 0.35 0.41 0.82 -0.01
13279 || orf19.3532 || MRPL10 || || Putative mitochondrial large subunit ribosomal protein; colony morphology-related gene regulation by Ssn6 || 1 -0.72 -0.48 -1.96 -1.98 -0.57 -1.53 1.04 1.31 0.35 0.62 1.15 0.36 0.58 0.32 0.48 -0.01
13280 || orf19.688 || || || Mitochondrial ribosomal protein of the small subunit; S. cerevisiae ortholog is essential for viability; Spider biofilm repressed || 1 -0.81 -0.88 -2.10 -2.11 -0.51 -1.65 0.94 1.58 0.55 0.94 1.44 0.65 0.37 0.40 0.79 0.24
13281 || orf19.5230 || MRPS9 || || Mitochondrial ribosomal protein S9; has N-terminal mitochondrial targeting signal and an S9 consensus motif; overexpression in S. cerevisiae causes respiratory defect that is reversible upon cessation of C. albicans gene expression || 1 -0.46 -0.56 -1.14 -1.36 -0.29 -0.78 0.82 1.02 0.20 0.65 0.46 0.31 0.08 0.28 0.41 0.04
13282 || orf19.7019 || YML6 || || Putative mitochondrial ribosomal protein; induced upon adherence to polystyrene || 1 -0.59 -0.59 -1.66 -2.36 -0.21 -1.07 1.19 1.36 0.56 0.92 1.00 0.49 0.52 0.48 0.74 0.23
13283 || orf19.484 || MRPL40 || || Putative mitochondrial ribosomal protein; Spider biofilm repressed || 1 -1.01 -1.03 -1.89 -2.02 -0.61 -0.91 0.80 1.00 0.41 1.15 0.67 0.26 0.06 0.29 0.31 -0.01
13284 || orf19.3350 || MRP20 || || Component of mitochondrial ribosome; decreased expression in hyphae compared to yeast-form cells || 1 -0.85 -0.88 -1.64 -1.87 -0.43 -1.17 0.91 1.02 0.10 0.53 0.86 0.47 -0.01 0.02 0.43 0.03
13285 || orf19.3350 || MRP20 || || Component of mitochondrial ribosome; decreased expression in hyphae compared to yeast-form cells || 1 -1.38 -1.06 -2.20 -1.90 -0.40 -1.05 1.16 1.18 0.29 0.69 1.26 0.43 0.39 0.12 0.57 -0.12
13286 || orf19.484 || MRPL40 || || Putative mitochondrial ribosomal protein; Spider biofilm repressed || 1 -1.00 -0.91 -2.11 -2.05 -0.24 -0.70 1.15 1.08 0.27 1.05 0.85 0.52 0.46 0.16 0.70 0.05
13287 || orf19.3797 || || || Ortholog(s) have structural constituent of ribosome activity and mitochondrial large ribosomal subunit localization || 1 -1.23 -1.06 -2.12 -1.85 -0.66 -1.21 1.14 1.27 0.37 1.24 0.76 0.82 0.29 -0.31 0.76 0.08
13288 || orf19.477 || || || Ortholog(s) have role in mitochondrial translation and mitochondrion localization || 1 -0.73 -0.90 -1.26 -1.39 -0.26 -0.69 0.55 0.87 0.37 0.71 0.48 0.65 -0.02 -0.27 0.83 0.39
13289 || orf19.7486 || MRPL6 || || Putative mitochondrial ribosomal protein || 1 -1.15 -1.15 -1.41 -1.59 -0.31 -0.87 0.73 0.99 0.42 0.85 0.95 0.71 0.25 0.13 0.91 0.63
13290 || orf19.7486 || MRPL6 || || Putative mitochondrial ribosomal protein || 1 -1.23 -1.42 -1.72 -1.74 -0.30 -1.11 0.62 0.88 0.22 0.84 0.96 0.70 0.01 0.24 0.67 0.26
13291 || orf19.6503 || || || Ortholog(s) have structural constituent of ribosome activity, role in mitochondrial translation and mitochondrial large ribosomal subunit localization || 1 -1.20 -1.40 -2.45 -2.28 -0.33 -1.06 1.27 1.13 0.05 0.80 1.32 0.80 0.99 0.56 1.42 -0.02
13292 || orf19.6853 || || || Protein of unknown function; Spider biofilm repressed || 1 -0.49 -0.39 -1.28 -1.44 0.20 -0.56 0.69 1.05 0.67 0.78 0.69 0.40 0.42 0.12 0.58 -0.06
13293 || orf19.4018 || || || Ortholog(s) have structural constituent of ribosome activity and mitochondrial small ribosomal subunit localization || 1 -0.62 -0.49 -1.45 -1.62 0.10 -0.47 0.86 1.16 0.56 1.00 1.17 0.48 0.61 0.32 0.87 -0.05
13294 || orf19.3350 || MRP20 || || Component of mitochondrial ribosome; decreased expression in hyphae compared to yeast-form cells || 1 -0.90 -0.77 -1.88 -1.65 -0.22 -0.99 1.10 1.49 0.54 0.85 1.39 0.60 0.64 0.31 0.81 0.15
13295 || orf19.585 || || || Ortholog(s) have structural constituent of ribosome activity and mitochondrial large ribosomal subunit localization || 1 -0.78 -0.80 -1.96 -1.89 -0.09 -1.15 1.39 1.47 0.46 1.03 1.22 0.56 0.89 0.47 1.14 0.03
13296 || orf19.2852 || || || Ortholog(s) have structural constituent of ribosome activity, role in mitochondrial translational initiation and mitochondrial small ribosomal subunit localization || 1 -0.45 -0.58 -1.63 -1.54 0.28 -0.94 1.24 1.48 0.31 0.78 1.33 0.40 0.58 0.48 1.13 0.16
13297 || orf19.755 || MRPL37 || || Putative mitochondrial large subunit ribosomal protein; shows colony morphology-related gene regulation by Ssn6p || 1 -0.50 -0.49 -1.66 -1.69 -0.26 -0.80 1.48 1.35 0.65 1.17 1.11 0.93 0.85 0.59 1.24 0.23
13298 || orf19.6503 || || || Ortholog(s) have structural constituent of ribosome activity, role in mitochondrial translation and mitochondrial large ribosomal subunit localization || 1 -1.07 -1.01 -2.09 -2.12 -0.05 -1.13 1.44 1.51 0.12 0.44 1.47 0.80 1.03 -0.01 1.43 0.15
13299 || orf19.1967 || || || Ortholog(s) have structural constituent of ribosome activity and mitochondrial large ribosomal subunit localization || 1 -0.79 -0.79 -2.13 -1.96 -0.12 -1.38 1.36 1.75 0.13 0.69 1.83 0.88 0.77 -0.15 1.35 -0.13
13300 || orf19.2852 || || || Ortholog(s) have structural constituent of ribosome activity, role in mitochondrial translational initiation and mitochondrial small ribosomal subunit localization || 1 -0.33 -0.40 -1.45 -1.19 0.13 -1.00 1.23 1.33 0.23 0.53 1.30 0.12 0.67 0.09 0.94 -0.17
13301 || orf19.2275 || || || Putative mitochondrial ribosomal protein; predicted role in aerobic respiration; Spider biofilm repressed || 1 -0.77 -1.22 -2.09 -1.74 -0.50 -1.21 1.25 1.61 0.71 0.92 1.49 0.37 0.20 0.18 0.29 0.03
13302 || orf19.2275 || || || Putative mitochondrial ribosomal protein; predicted role in aerobic respiration; Spider biofilm repressed || 1 -0.69 -0.65 -1.60 -1.42 -0.18 -1.00 1.22 1.46 0.66 0.73 1.30 0.77 0.32 0.10 0.19 -0.19
13303 || orf19.3350 || MRP20 || || Component of mitochondrial ribosome; decreased expression in hyphae compared to yeast-form cells || 1 -0.57 -0.66 -1.54 -1.27 -0.40 -1.07 1.31 1.63 0.51 0.64 1.04 0.52 0.50 0.14 0.43 -0.13
13304 || orf19.3696 || TOM22 || || Putative mitochondrial import receptor subunit; colony morphology-related gene regulation by Ssn6 || 1 -0.53 -0.43 -1.64 -1.45 -0.46 -1.18 1.56 1.90 0.49 0.49 1.63 0.55 0.02 0.42 0.00 0.11
13305 || orf19.3696 || TOM22 || || Putative mitochondrial import receptor subunit; colony morphology-related gene regulation by Ssn6 || 1 -0.63 -0.52 -2.12 -1.75 -0.33 -1.20 1.43 1.82 0.67 0.65 1.78 0.58 -0.03 0.47 0.16 0.00
13306 || orf19.5684 || || || Ortholog(s) have structural constituent of ribosome activity and mitochondrial large ribosomal subunit localization || 1 -0.56 -0.44 -1.32 -1.21 -0.45 -0.70 1.03 1.44 0.67 0.56 1.37 0.56 -0.15 0.26 0.34 0.34
13307 || orf19.4931 || || || Putative tRNA-Cys synthetase; induced by alpha pheromone in SpiderM medium; ribosomal subunits, translation factors, tRNA synthetases are downregulated upon phagocytosis by murine macrophage || 1 -0.35 -0.27 -1.11 -0.96 -0.47 -0.92 0.96 0.70 0.58 0.41 0.86 0.39 -0.00 -0.01 0.15 0.22
13308 || orf19.2438 || || || Ortholog(s) have mitochondrion, ribosome localization || 1 -0.39 -0.49 -1.22 -1.26 -0.76 -0.97 0.78 1.06 0.31 0.59 1.08 0.50 0.50 0.36 0.69 -0.56
13309 || orf19.828 || || || Putative ribosomal protein, large subunit, mitochondrial precursor; repressed by prostaglandins; Spider biofilm repressed || 1 -0.37 -0.31 -1.29 -1.65 -0.93 -1.51 1.11 1.21 1.04 1.43 1.19 0.67 1.06 0.42 0.78 -0.08
13310 || orf19.828 || || || Putative ribosomal protein, large subunit, mitochondrial precursor; repressed by prostaglandins; Spider biofilm repressed || 1 -0.61 -0.54 -1.48 -1.13 -0.80 -1.49 1.20 1.15 0.50 1.15 1.07 0.12 0.97 0.20 0.88 0.07
13311 || orf19.2019 || || || Ortholog(s) have structural constituent of ribosome activity and mitochondrial large ribosomal subunit localization || 1 -0.61 -0.57 -1.81 -1.58 -0.82 -1.88 1.29 1.42 0.39 0.64 0.52 -0.23 0.39 -0.15 0.52 -0.47
13312 || orf19.2019 || || || Ortholog(s) have structural constituent of ribosome activity and mitochondrial large ribosomal subunit localization || 1 -0.76 -0.79 -2.07 -2.14 -1.03 -1.85 1.37 1.48 0.53 0.81 0.89 0.27 0.49 0.23 0.57 -0.28
13313 || orf19.5230 || MRPS9 || || Mitochondrial ribosomal protein S9; has N-terminal mitochondrial targeting signal and an S9 consensus motif; overexpression in S. cerevisiae causes respiratory defect that is reversible upon cessation of C. albicans gene expression || 1 -0.98 -0.96 -1.27 -1.42 -0.94 -1.08 0.77 1.13 0.65 0.86 0.31 0.20 0.38 -0.17 0.12 -0.41
13314 || orf19.1323 || || || Phosphorylated protein of unknown function; Hap43p-repressed gene || 1 -0.41 -0.28 -1.03 -0.81 -0.55 -0.60 0.16 0.16 -0.04 0.05 0.55 0.15 0.23 0.16 0.42 0.07
13315 || orf19.5623 || ARP4 || || Subunit of the NuA4 histone acetyltransferase complex || 1 -0.70 -0.87 -1.22 -1.14 -0.55 -0.57 0.35 0.57 -0.26 -0.02 0.80 0.54 0.51 0.44 0.60 0.17
13316 || orf19.976 || BRE1 || || Putative transcription factor with C3HC4 zinc finger DNA-binding motif; similar to S. cerevisiae Bre1p; transposon mutation affects filamentous growth || 1 -0.80 -0.96 -1.30 -1.17 -0.26 -0.57 0.22 0.24 -0.35 0.15 0.77 0.18 0.47 0.22 0.74 0.14
13317 || orf19.976 || BRE1 || || Putative transcription factor with C3HC4 zinc finger DNA-binding motif; similar to S. cerevisiae Bre1p; transposon mutation affects filamentous growth || 1 -0.67 -0.56 -0.97 -1.23 0.01 -0.67 0.22 0.30 -0.03 -0.00 1.03 0.36 0.66 0.29 0.73 0.03
13318 || orf19.7367 || UBP1 || || Ortholog(s) have ubiquitin-specific protease activity, role in protein deubiquitination and endoplasmic reticulum localization || 1 -0.59 -0.59 -1.66 -1.55 -0.22 -0.66 0.43 0.35 -0.34 0.40 0.69 0.19 0.57 0.03 0.96 0.07
13319 || orf19.7367 || UBP1 || || Ortholog(s) have ubiquitin-specific protease activity, role in protein deubiquitination and endoplasmic reticulum localization || 1 -0.43 -0.35 -1.14 -1.34 -0.05 -0.40 0.23 0.31 0.12 0.44 0.53 0.44 0.48 0.12 0.60 -0.23
13320 || orf19.6295 || MAS2 || || Putative processing peptidase, catalytic (alpha) subunit; protein level decreases in stationary phase cultures || 1 -0.66 -0.62 -1.51 -1.71 -0.53 -0.67 0.33 0.33 0.17 0.72 0.77 0.78 0.13 0.25 0.69 0.22
13321 || orf19.482 || RPT4 || || 26S proteasome regulatory subunit; regulated by Gcn2p and Gcn4p; protein level decreases in stationary phase cultures || 1 -0.50 -0.51 -0.97 -1.00 -0.45 -0.59 0.28 0.40 0.11 0.39 0.88 0.45 0.03 0.24 0.66 0.42
13322 || orf19.1699 || BZZ1 || || Protein similar to S. cerevisiae Bzz1p, which is an SH3 domain protein involved in the regulation of actin polymerization || 1 -0.79 -0.78 -1.39 -1.37 -0.47 -0.66 0.53 0.37 0.32 0.03 0.57 0.62 0.31 0.38 1.10 0.68
13323 || orf19.1303 || || || Ortholog(s) have translation release factor activity, role in mitochondrial translational termination and mitochondrion localization || 1 -1.00 -0.85 -1.33 -1.01 -0.32 -0.26 0.59 0.51 0.16 0.82 0.74 0.95 0.11 0.28 0.55 0.16
13324 || orf19.2639 || || || Ortholog(s) have structural constituent of ribosome activity and mitochondrial large ribosomal subunit localization || 1 -1.77 -1.53 -1.32 -1.71 -0.71 -1.20 1.29 0.94 0.24 1.11 0.71 1.09 0.90 0.36 1.16 0.08
13325 || orf19.1828 || BUD16 || || Putative pyridoxal kinase; a key enzyme in pyridoxal 5'-phosphate synthesis, the active form of vitamin B6; involved in bud-site selection and genome integrity in S. cerevisiae; induced by alpha pheromone in SpiderM medium || 1 -0.57 -0.57 -1.15 -1.32 -0.53 -1.32 0.59 0.33 0.14 0.54 0.42 0.99 0.76 0.15 0.57 0.23
13326 || orf19.1828 || BUD16 || || Putative pyridoxal kinase; a key enzyme in pyridoxal 5'-phosphate synthesis, the active form of vitamin B6; involved in bud-site selection and genome integrity in S. cerevisiae; induced by alpha pheromone in SpiderM medium || 1 -0.54 -0.52 -1.14 -0.76 -0.56 -0.84 0.50 0.40 0.22 0.91 0.50 1.05 0.51 0.32 0.79 0.34
13327 || orf19.3487 || || || Ortholog of C. dubliniensis CD36 : Cd36_33330, C. parapsilosis CDC317 : CPAR2_701980, Debaryomyces hansenii CBS767 : DEHA2C15840g and Pichia stipitis Pignal : PICST_31066 || 1 -1.01 -0.95 -2.09 -1.00 -1.12 0.86 0.95 0.52 0.69 0.72 0.64 0.91 0.53 0.60 0.95
13328 || orf19.886 || PAN1 || || Essential protein involved in endocytosis and polarized growth; ortholog of S. cerevisiae Pan1, which is a part of a complex that regulates actin cytoskeleton; Spider biofilm repressed || 1 -0.41 -0.35 -0.54 -0.70 -0.25 -0.41 0.17 0.18 0.02 0.12 0.10 0.04 -0.15 0.12 0.29 0.25
13329 || orf19.522 || PIM1 || || ATP-dependent Lon protease; role in degradation of misfolded proteins in mitochondria, biogenesis and maintenance of mitochondria; rat catheter biofilm induced || 1 -0.73 -0.72 -1.20 -1.17 -0.25 -0.66 0.05 0.24 0.01 0.33 0.37 0.17 -0.48 0.28 0.65 0.30
13330 || orf19.522 || PIM1 || || ATP-dependent Lon protease; role in degradation of misfolded proteins in mitochondria, biogenesis and maintenance of mitochondria; rat catheter biofilm induced || 1 -0.46 -0.68 -0.83 -0.90 -0.17 -0.58 -0.08 0.03 0.07 0.05 0.34 0.04 -0.37 -0.09 0.41 0.06
13331 || orf19.3593 || RPT6 || || Putative ATPase of the 19S regulatory particle of the 26S proteasome; transcript regulated by Mig1; regulated by Gcn2 and Gcn4 || 1 -0.74 -0.81 -1.59 -1.48 -0.32 -0.84 -0.09 -0.03 -0.46 0.05 0.38 0.21 -0.84 0.24 0.30 0.09
13332 || orf19.6099 || CCT8 || || Chaperonin-containing T-complex subunit; role in hyphal morphogenesis, particularly starvation-induced; essential; expression in S. cerevisiae inhibits Ras2-mediated pathways; CCT8 and TRP1 overlap; Spider biofilm repressed || 1 -0.74 -0.78 -1.21 -0.87 -0.12 -0.71 0.25 0.34 -0.06 0.31 0.44 0.24 -0.84 -0.11 0.19 0.12
13333 || orf19.4406 || NIF3 || || Protein of unknown function; ortholog of S. cerevisiae Nif3; rat catheter biofilm repressed || 1 -1.02 -0.91 -1.62 -1.25 -0.20 -0.89 0.45 0.68 -0.21 0.12 0.88 0.15 -0.53 0.29 0.24 -0.07
13334 || orf19.1804 || || || Ortholog(s) have role in cellular response to cadmium ion, detoxification of cadmium ion and mitochondrion localization || 1 -1.02 -1.11 -1.61 -1.23 -0.44 -0.71 0.18 0.36 0.24 0.12 0.35 0.00 -0.19 -0.00 -0.16 -0.32
13335 || orf19.863 || || || Ortholog(s) have structural constituent of ribosome activity and mitochondrial large ribosomal subunit localization || 1 -0.94 -1.14 -2.02 -1.87 -0.00 -0.64 0.45 0.73 0.14 0.83 0.33 -0.14 -0.12 -0.37 0.22 -0.99
13336 || orf19.185 || || || Ortholog(s) have structural constituent of ribosome activity, role in mitochondrial translational initiation and mitochondrial small ribosomal subunit localization || 1 -0.55 -0.58 -1.22 -1.41 -0.22 -0.83 0.51 0.60 -0.08 0.57 -0.01 -0.10 -0.15 -0.34 0.37 -0.43
13337 || orf19.6136 || || || Ortholog of S. cerevisiae Mrpl4, a mitochondrial ribosomal protein of the large subunit; repressed by nitric oxide || 1 -0.97 -0.80 -1.51 -1.64 -0.26 -0.74 0.36 0.47 -0.18 0.48 0.09 0.08 0.26 -0.25 0.72 -0.44
13338 || orf19.1662 || || || Ortholog(s) have structural constituent of ribosome activity and mitochondrial small ribosomal subunit localization || 1 -1.40 -1.54 -2.56 -2.00 -0.47 -1.00 0.47 0.54 -0.44 0.87 0.39 0.27 0.47 -0.24 0.52 -0.51
13339 || orf19.477 || || || Ortholog(s) have role in mitochondrial translation and mitochondrion localization || 1 -1.05 -1.01 -1.81 -1.49 -0.65 -0.81 0.48 0.46 0.02 0.56 0.61 0.46 0.01 -0.60 0.53 -0.08
13340 || orf19.498 || || || Putative mitochondrial ribosomal component of the small subunit; possibly an essential gene, disruptants not obtained by UAU1 method; Spider biofilm repressed || 1 -1.14 -1.18 -1.96 -1.85 -0.94 -1.33 0.65 0.91 0.05 0.66 0.69 -0.12 0.18 -0.26 0.30 -0.36
13341 || orf19.5420 || || || Ortholog(s) have role in fatty acid metabolic process || 1 -0.94 -0.73 -1.34 -1.60 -0.20 -0.86 0.39 0.60 0.38 0.64 0.41 -0.05 0.20 -0.23 0.28 -0.13
13342 || orf19.5420 || || || Ortholog(s) have role in fatty acid metabolic process || 1 -1.18 -1.12 -1.91 -1.84 -0.39 -1.08 0.22 0.32 0.17 0.69 0.29 -0.25 -0.02 -0.14 0.21 -0.12
13343 || orf19.989 || || || Mitochondrial ribosomal protein of the small subunit; Spider biofilm repressed || 1 -1.34 -1.12 -1.84 -2.13 -0.52 -0.82 0.05 0.38 -0.14 0.60 0.69 0.31 -0.46 -0.10 0.20 0.10
13344 || orf19.989 || || || Mitochondrial ribosomal protein of the small subunit; Spider biofilm repressed || 1 -1.49 -1.27 -1.98 -2.28 -0.36 -0.83 0.18 0.63 0.08 0.50 0.50 0.33 -0.22 0.08 0.13 0.22
13345 || orf19.1956 || || || Ortholog(s) have role in reciprocal meiotic recombination and mitochondrion localization || 1 -1.31 -1.13 -2.21 -2.14 -0.23 -0.66 0.47 0.57 0.23 0.78 0.21 0.20 -0.34 0.16 0.34 -0.15
13346 || orf19.3700 || TOM70 || || Ortholog(s) have mitochondrion targeting sequence binding, protein channel activity and role in protein import into mitochondrial inner membrane, protein import into mitochondrial matrix || 1 -0.89 -0.98 -1.71 -1.48 -0.24 -0.69 0.32 0.40 0.05 0.84 0.53 0.17 -0.33 0.17 0.49 0.23
13347 || orf19.805 || || || Putative protein of unknown function; possibly mitochondrial; Hap43-repressed; Spider biofilm repressed || 1 -0.77 -0.64 -0.98 -1.04 0.14 -0.59 0.04 0.40 0.04 0.29 0.02 0.31 0.02 -0.01 0.34 0.19
13348 || orf19.3573 || PEX6 || || Ortholog(s) have ATPase activity, protein heterodimerization activity, role in fatty acid metabolic process, protein import into peroxisome matrix, receptor recycling, replicative cell aging and cytosol, nucleus, peroxisome localization || 1 -1.18 -0.73 -1.42 -1.35 0.14 -0.72 0.44 0.53 -0.04 0.42 0.32 0.57 -0.44 0.11 0.52 -0.04
13349 || orf19.6283 || || || Ortholog(s) have mitochondrion localization || 1 -0.64 -0.42 -0.89 -0.85 -0.18 -0.35 -0.03 0.23 0.09 0.23 0.12 0.39 -0.10 0.27 0.13 -0.09
13350 || orf19.1300 || || || Putative mitochondrial membrane protein; homozygous transposon insertion causes decreased colony wrinkling under filamentous growth-inducing conditions, but does not block true hyphal formation in liquid media || 1 -0.57 -0.69 -0.93 -1.09 -0.13 -0.44 0.19 0.28 0.03 0.39 0.29 0.35 -0.14 -0.19 0.44 -0.58
13351 || orf19.7485 || || || Putative mitochondrial ribosomal protein of the large subunit; Hap43p-repressed gene; ortholog of S. cerevisiae MRPL9 || 1 -0.44 -0.56 -1.10 -1.44 -0.28 -0.27 0.16 0.43 -0.02 0.48 0.41 0.18 -0.46 -0.02 0.18 -0.01
13352 || orf19.2544 || || || Ortholog(s) have aminoacyl-tRNA hydrolase activity, role in negative regulation of proteasomal ubiquitin-dependent protein catabolic process and mitochondrial outer membrane localization || 1 -0.41 -0.73 -1.04 -0.77 -0.26 -0.44 0.05 0.16 -0.27 0.50 0.40 0.24 -0.19 -0.15 0.27 -0.10
13353 || orf19.3147 || || || Ortholog of C. dubliniensis CD36 : Cd36_21050, C. parapsilosis CDC317 : CPAR2_104310, Candida tenuis NRRL Y-1498 : CANTEDRAFT_104515 and Debaryomyces hansenii CBS767 : DEHA2F01650g || 1 -0.39 -0.71 -1.03 -0.82 -0.28 -0.61 0.02 -0.17 -0.41 0.23 0.26 0.36 -0.22 -0.08 0.18 -0.03
13354 || orf19.7478 || || || Ortholog(s) have antioxidant activity, di-trans,poly-cis-decaprenylcistransferase activity, protein heterodimerization activity, trans-hexaprenyltranstransferase activity || 1 -0.69 -0.33 -1.43 -1.57 -0.49 -0.78 0.36 0.47 -0.12 0.52 0.43 0.67 0.10 -0.32 0.37 -0.16
13355 || orf19.7236 || TIF35 || || Putative translation initiation factor; repressed upon phagocytosis by murine macrophage; Spider biofilm repressed || 1 -1.25 -1.31 -1.72 -1.56 -0.12 -1.01 0.31 1.08 -0.15 0.66 0.74 -0.36 -0.50 0.09 -0.25 -0.73
13356 || orf19.6099 || CCT8 || || Chaperonin-containing T-complex subunit; role in hyphal morphogenesis, particularly starvation-induced; essential; expression in S. cerevisiae inhibits Ras2-mediated pathways; CCT8 and TRP1 overlap; Spider biofilm repressed || 1 -0.59 -0.69 -0.89 -0.89 0.09 -0.69 0.29 0.42 -0.01 0.40 0.44 -0.20 -0.55 -0.32 -0.01 -0.20
13357 || orf19.2709 || ZUO1 || || Ortholog of S. cerevisiae Zuo1; a cytosolic ribosome-associated chaperone; likely to be essential for growth, based on an insertional mutagenesis strategy; Spider biofilm repressed || 1 -0.51 -0.44 -1.38 -1.24 -0.52 -1.02 0.47 0.87 -0.27 0.56 1.00 -0.04 -0.28 -0.25 -0.38 0.03
13358 || orf19.5746 || ALA1 || || Alanyl-tRNA synthetase; translational regulation generates cytoplasmic and mitochondrial forms; Gcn4p-regulated; repressed by amino acid starvation (3-AT); translation-related genes downregulated upon phagocytosis by murine macrophages || 1 -0.45 -0.35 -1.33 -1.20 -0.33 -0.98 0.53 0.78 -0.46 0.45 0.65 -0.04 -0.63 -0.38 -0.21 0.04
13359 || orf19.3812 || SSZ1 || || Putative HSP70 chaperone; protein level decreases in stationary phase cultures; Spider biofilm repressed || 1 -0.76 -0.69 -1.61 -1.53 -0.31 -1.13 0.51 0.63 -0.76 0.37 0.89 -0.35 -0.31 -0.15 -0.01 0.14
13360 || orf19.3812 || SSZ1 || || Putative HSP70 chaperone; protein level decreases in stationary phase cultures; Spider biofilm repressed || 1 -0.59 -0.70 -1.50 -1.32 -0.39 -0.74 0.36 0.70 -0.53 0.33 0.78 0.35 -0.46 -0.51 0.04 0.39
13361 || orf19.4635 || NIP1 || || Putative translation initiation factor; mutation confers hypersensitivity to roridin A and verrucarin A; genes encoding ribosomal subunits, translation factors, and tRNA synthetases are downregulated upon phagocytosis by murine macrophage || 1 -0.52 -0.41 -1.69 -0.92 -0.50 -1.03 0.28 0.65 -0.70 0.76 0.97 0.29 -0.06 -0.10 0.27 0.44
13362 || orf19.3423 || TIF3 || || Putative translation initiation factor; genes encoding ribosomal subunits, translation factors, and tRNA synthetases are downregulated upon phagocytosis by murine macrophage || 1 -0.68 -0.66 -1.78 -1.16 -0.62 -1.06 0.28 1.00 -0.96 1.14 0.92 -0.09 0.46 0.67 0.18 0.24
13363 || orf19.4283 || || || Ortholog(s) have role in translational initiation and cytosol, eukaryotic 43S preinitiation complex, eukaryotic translation initiation factor 3 complex, eIF3e, eukaryotic translation initiation factor 3 complex, eIF3m, nucleus localization || 1 -0.55 -0.72 -1.97 -1.55 -1.14 -1.67 0.74 0.86 -0.58 0.75 1.06 0.11 1.08 0.19 0.68 -0.34
13364 || orf19.4283 || || || Ortholog(s) have role in translational initiation and cytosol, eukaryotic 43S preinitiation complex, eukaryotic translation initiation factor 3 complex, eIF3e, eukaryotic translation initiation factor 3 complex, eIF3m, nucleus localization || 1 -0.71 -0.70 -1.43 -0.96 -1.34 -1.71 0.24 0.58 -0.21 0.77 0.77 -0.29 0.54 0.05 0.33 -0.58
13365 || orf19.3124 || || || Ortholog(s) have mRNA binding, metalloaminopeptidase activity, role in negative regulation of gene expression, protein initiator methionine removal involved in protein maturation and cytosolic ribosome, nucleolus localization || 1 -0.37 -0.81 -1.07 -0.78 -0.87 -0.94 0.18 0.41 -0.49 0.61 0.77 0.03 0.21 -0.08 0.10 -0.14
13366 || orf19.5989 || || || Putative cleavage factor I subunit; required for the cleavage and polyadenylation of pre-mRNA 3' ends; Spider biofilm repressed || 1 -0.87 -0.88 -1.55 -1.06 -1.07 -1.33 0.29 0.45 -0.29 0.48 0.59 0.23 0.25 -0.25 0.07 -0.07
13367 || orf19.3124 || || || Ortholog(s) have mRNA binding, metalloaminopeptidase activity, role in negative regulation of gene expression, protein initiator methionine removal involved in protein maturation and cytosolic ribosome, nucleolus localization || 1 -0.82 -0.83 -2.11 -1.79 -1.03 -1.14 0.46 0.48 -0.37 0.97 0.83 0.12 0.30 0.40 0.18 0.13
13368 || orf19.6748 || || || Ortholog(s) have role in ascospore formation, cellular response to cadmium ion, detoxification of cadmium ion || 1 -0.75 -0.76 -1.84 -1.41 -0.66 -1.09 0.54 0.94 -0.32 0.21 0.79 -0.06 0.18 0.12 -0.10 -0.17
13369 || orf19.7153 || || || Putative exportin, member of the Exportin-T family; flow model biofilm repressed || 1 -1.09 -1.12 -1.97 -1.15 -0.50 -1.10 -0.21 0.69 -0.29 0.71 0.76 -0.19 0.09 -0.01 -0.07 0.07
13370 || orf19.7161 || SUI3 || || Putative translation initiation factor; genes encoding ribosomal subunits, translation factors, and tRNA synthetases are downregulated upon phagocytosis by murine macrophage || 1 -1.18 -1.26 -1.33 -1.05 -0.69 -1.04 -0.05 0.68 -0.46 0.77 0.79 0.04 -0.18 -0.13 -0.24 -0.20
13371 || orf19.2920 || || || Ortholog(s) have role in ribosome biogenesis and cytosol, ribosome localization || 1 -0.68 -0.67 -0.82 -0.65 -0.57 -0.56 -0.21 0.41 -0.47 0.29 0.67 0.07 -0.46 0.12 -0.13 0.01
13372 || orf19.269 || SES1 || || Seryl-tRNA synthetase; charges the tRNA that recognizes the CUG codon, which typically specifies Leu, but specifies Ser in C. albicans; complements S. cerevisiae ses1 mutant viability; soluble protein in hyphae; macrophage-regulated || 1 -0.48 -0.50 -1.46 -1.07 -0.52 -1.51 0.46 0.91 -0.28 0.62 0.67 0.12 -0.49 0.47 -0.21 0.11
13373 || orf19.3599 || TIF4631 || || Putative translation initiation factor eIF4G; overexpression causes hyperfilamentation; hyphal- and macrophage-induced; genes encoding some translation factors are downregulated upon phagocytosis by murine macrophage || 1 -0.44 -0.45 -0.94 -0.45 -0.37 -0.89 0.29 0.79 -0.23 0.54 0.75 0.00 -0.06 0.42 -0.17 0.27
13374 || orf19.7477 || YRB1 || || Functional homolog of S. cerevisiae Yrb1p; regulates Gsp1 GTPase activity and thereby affects nucleocytoplasmic transport and cytoskeletal dynamics; transcript is not regulated by white-opaque switch or by dimorphic transition || 1 -0.15 -0.25 -1.32 -1.14 -0.61 -1.02 0.74 1.08 -0.24 0.45 1.20 0.52 0.11 0.54 0.18 0.56
13375 || orf19.7626 || EIF4E || || Translation initiation factor eIF4E; genes encoding ribosomal subunits, translation factors, tRNA synthetases downregulated by phagocytosis by macrophage; alternatively spliced intron in 5' UTR; protein levels decrease in stationary phase || 1 -0.22 -0.34 -1.17 -0.88 -0.28 -0.97 0.69 1.24 -0.10 0.40 1.23 0.47 0.07 0.47 0.05 0.22
13376 || orf19.7626 || EIF4E || || Translation initiation factor eIF4E; genes encoding ribosomal subunits, translation factors, tRNA synthetases downregulated by phagocytosis by macrophage; alternatively spliced intron in 5' UTR; protein levels decrease in stationary phase || 1 -0.46 -0.50 -1.25 -1.20 -0.49 -1.15 0.55 1.12 -0.33 0.41 1.15 0.29 0.02 0.36 -0.24 -0.27
13377 || orf19.7234 || || || Putative RSC chromatin remodeling complex component; possibly an essential gene, disruptants not obtained by UAU1 method || 1 -0.41 -0.41 -0.87 -0.88 -0.38 -1.32 0.35 0.82 -0.35 0.00 1.13 0.19 0.15 0.16 0.04 0.13
13378 || orf19.2610 || || || Putative tRNA binding protein; intron-containing gene; Spider biofilm induced || 1 -0.41 -0.50 -0.89 -0.53 -0.12 -0.90 0.67 0.83 0.06 0.49 0.96 0.19 0.34 0.31 -0.03 0.54
13379 || orf19.3243 || SRP54 || || Putative signal recognition particle (SRP) subunit; induced in ssr1 null; Spider biofilm repressed || 1 -0.29 -0.21 -0.46 -0.55 -0.12 -0.74 0.23 0.44 0.05 0.30 0.76 0.19 -0.03 0.38 0.39 0.09
13380 || orf19.4193 || || || Ortholog(s) have Arp2/3 complex binding activity, role in actin cortical patch assembly, actin filament debranching, negative regulation of Arp2/3 complex-mediated actin nucleation and actin cortical patch, cytosol, nucleus localization || 1 -0.15 -0.13 -0.94 -0.42 -0.37 -0.98 0.04 0.59 -0.06 0.43 1.13 0.14 -0.19 0.52 0.31 0.21
13381 || orf19.5989 || || || Putative cleavage factor I subunit; required for the cleavage and polyadenylation of pre-mRNA 3' ends; Spider biofilm repressed || 1 -0.46 -0.48 -1.17 -0.73 -0.94 -1.07 0.85 0.90 -0.19 0.73 0.98 0.47 0.32 0.33 0.44 0.60
13382 || orf19.2558 || || || Has domain(s) with predicted zinc ion binding activity and nucleus localization || 1 -0.18 -0.12 -0.59 -0.88 -0.62 -0.65 0.36 0.39 0.08 0.36 0.54 0.34 -0.06 0.54 -0.07 0.26
13383 || orf19.4440 || SEC34 || || Ortholog(s) have role in CVT pathway, ER to Golgi vesicle-mediated transport, macroautophagy, peroxisome degradation, retrograde transport, vesicle recycling within Golgi and Golgi transport complex, cell division site localization || 1 -0.29 -0.14 -0.61 -0.65 -0.32 -0.72 0.05 0.26 -0.25 0.15 0.49 0.17 0.00 0.43 0.00 0.23
13384 || orf19.2070 || || || Ortholog(s) have role in G1/S transition of mitotic cell cycle, chromatin remodeling, nucleosome disassembly, transcription elongation from RNA polymerase II promoter and RSC complex localization || 1 -0.34 -0.17 -0.66 -0.73 -0.72 -1.23 0.19 0.45 -0.20 0.08 0.62 0.37 0.37 0.34 0.16 0.57
13385 || orf19.4939 || MON2 || || Peripheral membrane protein; role in endocytosis and vacuole integrity; flow model and rat catheter biofilm repressed || 1 0.06 -0.21 -0.63 -0.83 -0.95 -1.42 0.27 0.59 -0.01 0.02 0.52 0.01 0.04 0.56 -0.06 0.52
13386 || orf19.2798 || || || Putative helicase; fungal-specific (no human or murine homolog) || 1 -0.37 -0.25 -0.98 -1.45 -0.33 -1.62 0.79 0.89 0.23 0.17 0.95 0.61 0.52 0.22 0.24 0.37
13387 || orf19.714 || || || Ortholog(s) have GTPase activity and role in intracellular protein transport, retrograde transport, endosome to Golgi || 1 -0.71 -0.39 -0.70 -0.85 -0.12 -0.66 0.43 0.32 -0.01 0.75 0.84 0.67 0.50 0.11 0.31 0.20
13388 || orf19.6858 || EDC3 || || Ortholog(s) have role in cytoplasmic mRNA processing body assembly, deadenylation-independent decapping of nuclear-transcribed mRNA and cytoplasmic mRNA processing body localization || 1 -0.43 -0.27 -0.77 -1.04 -0.10 -0.34 0.12 0.08 -0.01 0.56 0.81 0.51 0.29 -0.01 0.14 -0.05
13389 || orf19.5887 || NUP85 || || Ortholog of S. cerevisiae Nup85; a structural constituent of the nuclear pore; required for alkaline-induced hyphal morphogenesis and for SD or Spider media biofilm formation || 1 -0.17 -0.33 -0.71 -0.80 -0.23 -0.28 -0.06 0.07 -0.18 0.11 0.51 0.52 -0.04 0.60 0.07 0.35
13390 || orf19.5350 || || || Ortholog(s) have cyclin-dependent protein serine/threonine kinase activity || 1 -0.51 -0.49 -0.98 -1.13 -0.50 -0.75 0.18 -0.04 -0.35 0.09 0.67 0.56 -0.18 0.50 0.19 0.15
13391 || orf19.5771 || PBP2 || || Putative RNA binding protein; transcript regulated by Nrg1, Mig1, and Tup1 || 1 -0.39 -0.33 -0.76 -0.76 -0.21 -0.26 0.01 0.30 -0.35 0.38 0.46 0.14 -0.32 0.32 0.08 0.29
13392 || orf19.2884 || CDC68 || || Functional homolog of S. cerevisiae Cdc68, a transcription elongation factor; essential; possible drug target || 1 -0.51 -0.57 -0.75 -0.71 0.16 -0.19 -0.01 0.23 -0.26 0.34 0.57 0.46 -0.22 0.17 0.37 0.20
13393 || orf19.798 || TAF14 || || Putative DNA-binding transcription factor; TFIIF subunit; macrophage-induced protein; possibly required for yeast cell adherence to silicone substrate; mutant has pleiotrophic effects || 1 -0.48 -0.66 -0.61 -0.67 -0.17 -0.27 0.07 0.48 -0.38 -0.04 0.67 0.44 -0.10 0.34 0.22 0.31
13394 || orf19.3593 || RPT6 || || Putative ATPase of the 19S regulatory particle of the 26S proteasome; transcript regulated by Mig1; regulated by Gcn2 and Gcn4 || 1 -0.39 -0.45 -0.74 -0.58 0.10 -0.34 0.15 0.40 -0.12 0.20 0.57 0.44 -0.20 0.35 0.16 0.57
13395 || orf19.4406 || NIF3 || || Protein of unknown function; ortholog of S. cerevisiae Nif3; rat catheter biofilm repressed || 1 -0.97 -0.93 -1.24 -0.94 -0.27 -0.68 0.70 0.56 0.06 0.35 1.08 0.39 -0.53 0.52 0.17 0.47
13396 || orf19.3197 || PAP1 || || Poly(A) polymerase, likely involved in mRNA polyadenylation; PAP is inhibited by parnafungin antifungals; non-sex gene located within the MTLa mating-type-like locus || 1 -0.50 -0.73 -1.19 -0.81 -0.27 -0.37 0.33 0.56 0.05 0.18 0.85 0.42 -0.14 0.48 0.58 0.26
13397 || orf19.997 || SNL1 || || Ribosome-associated protein predicted to function in protein synthesis; 1 predicted transmembrane domain; rat catheter biofilm repressed || 1 -0.50 -0.49 -1.04 -0.83 -0.18 -0.54 0.04 0.33 -0.51 0.21 1.12 1.03 -0.12 0.19 0.56 0.39
13398 || orf19.4888 || || || Has domain(s) with predicted nucleic acid binding, nucleotide binding activity || 1 -0.45 -0.46 -0.88 -0.84 -0.61 -0.52 0.30 0.15 -0.45 0.03 0.70 0.62 -0.04 0.36 0.84 0.67
13399 || orf19.5260 || RPN2 || || Putative 26S proteasome subunit; transcript regulated by Mig1; caspofungin repressed; regulated by Gcn2 and Gcn4; gene used for strain identification by multilocus sequence typing || 1 -0.39 -0.34 -1.14 -1.41 -0.42 -0.85 0.52 0.26 -0.11 0.09 0.73 0.57 -0.23 0.33 0.87 0.89
13400 || orf19.5516 || || || Ortholog(s) have signal sequence binding activity, role in protein targeting to ER and cytosol, nucleus, signal recognition particle, endoplasmic reticulum targeting localization || 1 -0.53 -0.55 -0.88 -0.84 -0.37 -0.99 0.57 0.78 -0.05 0.36 0.87 0.75 0.10 -0.03 0.05 0.54
13401 || orf19.7571 || UBC4 || || Ortholog(s) have ubiquitin binding activity || 1 -0.70 -0.57 -1.21 -0.83 -0.73 -0.87 0.54 0.81 -0.27 -0.13 1.22 0.48 -0.08 -0.08 0.32 0.59
13402 || orf19.7571 || UBC4 || || Ortholog(s) have ubiquitin binding activity || 1 -0.90 -0.86 -1.01 -0.55 -0.94 -0.64 0.34 0.88 0.01 0.19 1.11 0.66 -0.12 -0.13 0.39 0.71
13403 || orf19.7454 || TAF60 || || Putative TFIID and SAGA complex subunit; mutation confers hypersensitivity to amphotericin B || 1 -0.54 -0.70 -0.85 -0.93 -0.78 -0.76 0.19 0.39 -0.27 -0.15 0.88 0.67 0.33 0.23 0.40 0.55
13404 || orf19.7454 || TAF60 || || Putative TFIID and SAGA complex subunit; mutation confers hypersensitivity to amphotericin B || 1 -0.46 -0.55 -0.65 -0.68 -0.60 -0.77 0.23 0.31 -0.24 0.00 0.79 0.56 0.28 0.19 0.12 0.20
13405 || orf19.2041 || || || Ortholog(s) have DNA translocase activity, histone acetyl-lysine binding activity || 1 -0.46 -0.44 -0.60 -0.47 -0.63 -0.79 0.04 0.27 -0.12 0.01 0.81 0.59 0.34 0.24 0.01 0.57
13406 || orf19.6071 || || || Ortholog(s) have peptide alpha-N-acetyltransferase activity, role in N-terminal peptidyl-methionine acetylation, cytoskeleton organization, mitochondrion inheritance and NatB complex localization || 1 -0.62 -0.51 -0.79 -0.74 -0.58 -0.37 0.06 0.05 -0.05 -0.09 0.89 0.55 -0.19 0.13 0.10 0.49
13407 || orf19.5917.3 || || || RNA binding protein required for export of poly(A)+ mRNA from the nucleus; Spider biofilm repressed || 1 -0.99 -1.12 -1.21 -0.89 -0.53 -1.07 -0.05 0.50 -0.51 -0.27 1.20 0.78 -0.22 -0.40 0.03 0.46
13408 || orf19.7285 || || || Ortholog(s) have role in mRNA cleavage, mRNA polyadenylation, snoRNA 3'-end processing, termination of RNA polymerase II transcription, exosome-dependent, termination of RNA polymerase II transcription, poly(A)-coupled || 1 -1.07 -1.26 -1.59 -1.21 -1.30 -0.94 -0.10 0.11 -0.37 -0.11 0.92 0.70 0.12 -0.01 1.14 0.36
13409 || orf19.7285 || || || Ortholog(s) have role in mRNA cleavage, mRNA polyadenylation, snoRNA 3'-end processing, termination of RNA polymerase II transcription, exosome-dependent, termination of RNA polymerase II transcription, poly(A)-coupled || 1 -1.19 -1.26 -1.27 -0.97 -1.08 -0.72 0.04 0.29 -0.15 0.07 1.19 0.98 0.23 0.32 1.40 0.59
13410 || orf19.6694 || || || Ortholog of C. dubliniensis CD36 : Cd36_73320, C. parapsilosis CDC317 : CPAR2_703860, Candida tenuis NRRL Y-1498 : CANTEDRAFT_114480 and Debaryomyces hansenii CBS767 : DEHA2C13794g || 1 -0.51 -0.48 -0.71 -0.67 -0.09 -0.54 -0.19 -0.04 -0.25 -0.07 0.06 0.27 -0.04 0.01 0.35 0.17
13411 || orf19.3006 || GGA2 || || Protein involved in Golgi trafficking; rat catheter and Spider biofilm repressed || 1 -0.59 -0.61 -0.98 -0.92 -0.36 -0.56 0.04 -0.06 -0.50 -0.51 0.63 -0.10 -0.38 0.00 0.24 0.35
13412 || orf19.6197 || DHH1 || || Putative RNA helicase || 1 -0.55 -0.65 -0.95 -0.95 -0.58 -0.81 0.19 0.09 -0.60 -0.53 0.80 0.47 -0.06 -0.28 0.34 0.37
13413 || orf19.6197 || DHH1 || || Putative RNA helicase || 1 -0.72 -0.77 -0.88 -0.77 -0.86 -0.67 0.04 -0.19 -0.39 -0.46 0.50 0.41 -0.17 -0.09 0.38 0.46
13414 || orf19.978 || BDF1 || || Bromodomain transcription factor; repressed upon adherence to polystyrene; reduced mRNA abundance detected in null mutant; macrophage/pseudohyphal-repressed; possibly essential, disruptants not obtained by UAU1 method || 1 -0.79 -0.71 -1.05 -0.84 -0.78 -0.67 -0.11 0.12 -0.38 -0.12 0.65 0.13 -0.21 -0.19 0.31 0.03
13415 || orf19.1674 || CDC53 || || Cullin, a scaffold subunit of the SCF ubiquitin-ligase complexes; depletion leads to increased filamentous growth and premature cell death || 1 -0.58 -0.64 -1.12 -1.04 -0.60 -0.81 -0.01 0.03 -0.47 -0.28 0.46 0.42 -0.19 0.16 0.37 0.10
13416 || orf19.581 || || || Putative RNA-binding protein; transcript is upregulated in an RHE model of oral candidiasis || 1 -0.89 -1.02 -1.81 -1.79 -1.27 -1.03 0.13 0.10 -0.56 -0.36 0.83 0.09 0.33 0.18 0.49 0.20
13417 || orf19.2961 || || || Putative transcription factor with zinc finger DNA-binding motif || 1 -0.43 -0.63 -1.13 -1.01 -0.48 -0.79 0.06 -0.03 -0.38 -0.03 0.28 0.23 0.26 0.30 0.39 0.25
13418 || orf19.1210 || || || Ortholog(s) have L-arginine transmembrane transporter activity, L-aspartate transmembrane transporter activity and L-glutamate transmembrane transporter activity, more || 1 -0.54 -0.61 -1.12 -1.08 -0.47 -1.21 0.15 0.11 -0.51 -0.45 0.04 0.17 0.11 0.26 0.50 0.20
13419 || orf19.6358 || || || Ortholog(s) have protein homodimerization activity, ubiquitin-protein ligase activity and role in free ubiquitin chain polymerization, postreplication repair, protein K63-linked ubiquitination || 1 -0.36 -0.48 -1.01 -0.73 -0.68 -0.78 0.07 -0.07 -0.41 -0.52 0.10 0.21 0.05 0.31 0.21 0.10
13420 || orf19.2798 || || || Putative helicase; fungal-specific (no human or murine homolog) || 1 -1.02 -0.94 -2.01 -1.25 -0.60 -1.36 0.46 0.15 -0.02 -0.18 0.62 0.19 0.08 0.56 0.27 0.59
13421 || orf19.5350 || || || Ortholog(s) have cyclin-dependent protein serine/threonine kinase activity || 1 -0.35 -0.49 -1.08 -0.67 -0.18 -0.55 0.31 0.25 -0.53 -0.09 0.67 0.19 0.08 0.11 0.22 0.14
13422 || orf19.387 || GCR3 || || Functional homolog of S. cerevisiae Gcr3, which acts in regulation of glycolytic genes; no intron predicted, in contrast to intron in S. cerevisiae GCR3 gene || 1 -0.68 -0.72 -1.46 -1.49 0.00 -0.45 0.61 0.28 0.24 -0.12 0.37 0.05 0.34 0.21 -0.34 0.28
13423 || orf19.5705 || NAM2 || || Mitochondrial leucyl-tRNA synthetase || 1 -0.70 -0.64 -1.67 -1.38 0.14 -0.75 0.70 0.33 0.03 -0.02 0.35 -0.10 -0.43 -0.30 -0.10 0.05
13424 || orf19.5705 || NAM2 || || Mitochondrial leucyl-tRNA synthetase || 1 -0.58 -0.60 -1.26 -1.05 -0.10 -0.36 0.35 0.72 0.60 0.28 0.30 0.62 -0.46 -0.10 -0.09 0.11
13425 || orf19.1686 || || || Ortholog(s) have mitochondrion localization || 1 -0.30 -0.65 -1.03 -0.88 -0.47 -0.67 0.38 0.09 0.48 0.01 0.61 0.60 -0.81 0.14 -0.24 0.58
13426 || orf19.1686 || || || Ortholog(s) have mitochondrion localization || 1 -0.23 -0.36 -1.00 -0.94 -0.40 -0.53 0.64 0.21 0.38 -0.18 0.62 0.36 -0.44 -0.21 -0.15 0.43
13427 || orf19.3008 || COQ4 || || Protein with a putative role in coenzyme Q biosynthesis; transcriptionally induced by interaction with macrophage; Hap43p-repressed gene || 1 -0.51 -0.23 -1.15 -1.14 -0.37 -0.80 0.23 0.77 0.40 -0.20 0.84 0.48 -0.36 0.30 -0.12 0.15
13428 || orf19.3577 || COQ5 || || Putative methyltransferase of ubiquinone biosynthesis; regulated by Gcn4; repressed by amino acid starvation (3-AT), Hap43; induced upon adherence to polystyrene; Spider biofilm repressed || 1 -1.16 -0.64 -1.44 -1.23 -0.60 -1.04 0.22 0.44 -0.06 -0.03 0.59 0.54 -0.68 -0.19 -0.26 0.44
13429 || orf19.6057 || || || Ortholog(s) have 3-methyl-2-oxobutanoate hydroxymethyltransferase activity, role in pantothenate biosynthetic process, respiratory chain complex IV assembly and mitochondrion localization || 1 -1.20 -0.75 -1.39 -1.65 -0.21 -1.08 -0.00 0.80 0.31 0.11 1.05 0.08 -0.73 -0.79
13430 || orf19.5486 || || || Putative endoribonuclease; heterozygous null mutant exhibits hypersensitivity to parnafungin and cordycepin in the C. albicans fitness test || 1 -0.60 -0.51 -0.73 -1.14 0.06 -0.68 0.18 0.11 -0.04 0.22 0.40 0.27 -0.29 0.23 -0.09 0.41
13431 || orf19.2984 || MST1 || || Ortholog(s) have role in mitochondrial threonyl-tRNA aminoacylation and mitochondrion localization || 1 -0.47 -0.49 -0.97 -1.31 -0.44 -0.57 0.42 0.43 0.34 0.27 0.19 0.24 -0.43 -0.09 0.28 0.39
13432 || orf19.6698 || || || Ortholog(s) have asparagine-tRNA ligase activity, role in mitochondrial asparaginyl-tRNA aminoacylation and mitochondrion localization || 1 -0.45 -0.49 -0.76 -0.89 -0.26 -0.70 0.37 0.10 0.06 0.11 -0.06 0.42 -0.70 -0.06 0.31 0.29
13433 || orf19.1451 || SRB9 || || Subunit of the RNA polymerase II mediator complex; transposon mutation affects filamentous growth; suppresses S. cerevisiae diploid filamentous (flo8, ste7, ste12, tec1) or haploid invasive (flo8) mutant growth defects || 1 -0.22 -0.17 -0.57 -0.52 0.20 0.02 0.10 0.08 0.23 -0.12 -0.00 0.09 -0.29 0.04 0.22 0.06
13434 || orf19.7092 || || || Putative NAD dependent epimerase/dehydratase family protein; Spider biofilm repressed || 1 -0.50 -0.64 -1.24 -1.17 0.48 0.14 0.30 0.41 0.12 -0.10 0.54 0.26 -0.50 0.39 0.40 0.31
13435 || orf19.1552 || CPR3 || || Putative peptidyl-prolyl cis-trans isomerase; macrophage-induced protein; protein levels decrease in stationary phase yeast cultures; predicted mitochondrial localization; overlaps orf19.1551 || 1 -0.79 -0.92 -1.25 -1.00 0.16 -0.21 0.32 0.42 0.20 -0.14 0.19 0.20 -0.42 0.29 0.35 0.03
13436 || orf19.6238 || || || Ortholog(s) have mitochondrion localization || 1 -0.46 -0.57 -1.59 -1.33 -0.04 -0.15 0.26 0.31 0.01 0.03 0.54 0.74 -0.58 0.08 0.44 0.45
13437 || orf19.342 || BMT7 || || Beta-mannosyltransferase, member of a 9-gene family that includes characterized genes BMT1, BMT2, BMT3, and BMT4 with roles in beta-1,2-mannosylation of cell wall phosphopeptidomannan; downregulated in azole-resistant strain; Hap43p-induced || 1 -1.26 -1.25 -2.52 -1.73 -0.86 -0.92 -0.01 0.10 0.79 0.19 0.50 1.06 0.10 0.17 1.22 0.58
13438 || orf19.2532 || PRS || || Putative prolyl-tRNA synthetase; monofunctional Class II synthetase; gene is constitutively expressed || 1 -0.97 -1.04 -1.63 -1.79 0.20 -0.31 0.47 -0.16 0.96 0.46 0.46 1.08 -0.53 -0.10 0.61 0.11
13439 || orf19.2532 || PRS || || Putative prolyl-tRNA synthetase; monofunctional Class II synthetase; gene is constitutively expressed || 1 -0.90 -0.89 -1.18 -1.14 0.03 -0.44 0.46 0.29 0.64 0.37 0.27 0.76 -0.23 -0.18 0.44 0.18
13440 || orf19.2532 || PRS || || Putative prolyl-tRNA synthetase; monofunctional Class II synthetase; gene is constitutively expressed || 1 -1.27 -1.26 -1.80 -1.81 -0.06 -0.61 0.74 0.43 0.64 0.29 0.22 0.75 -0.18 -0.32 0.64 0.12
13441 || orf19.1669 || AFG3 || || Similar to S. cerevisiae Afg3p, a subunit of the mitochondrial inner membrane m-AAA protease; likely to be essential for growth, based on an insertional mutagenesis strategy || 1 -0.52 -0.61 -0.93 -0.86 0.04 -0.17 0.01 0.07 0.15 0.30 -0.10 0.19 -0.16 -0.21 0.52 -0.06
13442 || orf19.2415 || || || Ortholog(s) have role in mitochondrial translation and mitochondrion localization || 1 -1.09 -1.43 -1.31 -1.44 -0.03 -0.39 0.12 0.23 0.64 0.63 -0.06 0.30 -0.55 0.13 0.37 0.08
13443 || orf19.6934 || || || Ortholog(s) have role in protein insertion into mitochondrial membrane from inner side and integral to mitochondrial inner membrane localization || 1 -0.99 -1.24 -1.20 -1.22 0.13 -0.16 0.04 0.33 0.48 0.44 0.20 0.32 -0.18 -0.03 0.29 -0.44
13444 || orf19.4299 || MSW1 || || Protein similar to S. cerevisiae Msw1p, which is mitochondrial tryptophanyl-tRNA synthetase; Hap43p-repressed gene; likely to be essential for growth, based on an insertional mutagenesis strategy || 1 -1.31 -1.50 -0.85 -1.32 -0.06 -0.02 0.03 0.02 0.27 0.28 0.04 0.31 -0.27 -0.04 0.25 -0.21
13445 || orf19.6659 || GAP6 || || Broad-specificity amino acid permease; Plc1, Gcn4 regulated; rat catheter biofilm induced || 1 -3.36 -3.52 -4.03 -4.36 -1.55 -1.34 1.38 -0.80 0.46 -0.44 -0.12 -0.22 -0.92 0.01 0.81 0.89
13446 || orf19.6659 || GAP6 || || Broad-specificity amino acid permease; Plc1, Gcn4 regulated; rat catheter biofilm induced || 1 -2.33 -1.76 -3.40 -3.20 -1.11 -1.01 1.59 -0.52 0.87 -0.00 0.13 -0.14 -0.45 0.44 0.98 0.52
13447 || orf19.2455 || || || Ortholog(s) have gamma-glutamyltransferase activity, omega peptidase activity, role in glutathione catabolic process and cytoplasm, nucleus localization || 1 -0.90 -0.79 -1.63 -1.41 0.14 -0.33 0.38 0.14 0.46 -0.14 0.37 -0.08 0.05 0.08 0.43 0.26
13448 || orf19.5579 || || || Protein with a predicted double-strand break repair domain; Hap43-repressed gene || 1 -0.90 -0.86 -1.39 -1.53 0.07 -0.30 0.10 0.03 -0.11 -0.20 -0.02 -0.13 -0.13 0.16 0.49 0.25
13449 || orf19.6533 || MSK1 || || Putative mitochondrial lysine-tRNA synthetase; flucytosine repressed || 1 -0.62 -0.70 -1.33 -1.40 0.13 -0.61 0.18 -0.03 0.21 0.05 0.10 0.10 -0.43 0.09 0.26 0.25
13450 || orf19.7212 || || || Phosphorylated protein; homozygous transposon insertion causes decreased colony wrinkling in filamentous growth-inducing conditions, but does not block hyphal formation in liquid media; Hap43-repressed || 1 -0.74 -0.60 -1.24 -1.49 0.02 -0.15 0.18 0.08 0.36 -0.20 0.05 0.04 -0.25 0.34 -0.03 0.41
13451 || orf19.7583 || ZCF39 || || Zn(II)2Cys6 transcription factor; mutants are viable; filament induced; required for yeast cell adherence to silicone substrate; Spider biofilm induced || 1 -1.45 -1.30 -1.43 -1.54 0.34 0.31 0.52 0.32 -0.22 -0.60 0.81 0.16 -0.24 0.62 0.55 0.68
13452 || orf19.4414 || || || Ortholog of C. dubliniensis CD36 : Cd36_45590, C. parapsilosis CDC317 : CPAR2_501450, Candida tenuis NRRL Y-1498 : CANTEDRAFT_105024 and Debaryomyces hansenii CBS767 : DEHA2D12364g || 1 -0.92 -1.25 -1.35 -1.47 0.25 0.22 0.08 -0.30 -0.03 -0.33 0.43 0.32 -0.18 0.53 0.32 0.42
13453 || orf19.6986 || || || Has domain(s) with predicted Rab GTPase activator activity, role in regulation of Rab GTPase activity and intracellular localization || 1 -1.26 -1.44 -1.60 -1.71 0.38 -0.33 -0.21 0.08 -0.25 -0.55 0.56 0.45 -0.53 0.16 0.29 0.60
13454 || orf19.2977 || MIA40 || || Predicted component of the mitochondrial intermembrane space import machinery; Hap43p-repressed gene || 1 -1.47 -1.54 -1.74 -1.50 0.16 0.44 0.14 0.15 -0.05 -0.02 0.51 0.76 -0.43 0.07 0.64 0.49
13455 || orf19.2977 || MIA40 || || Predicted component of the mitochondrial intermembrane space import machinery; Hap43p-repressed gene || 1 -1.05 -1.15 -1.74 -1.77 0.22 0.47 0.35 0.36 0.03 0.08 0.79 0.88 -0.12 0.29 1.03 0.41
13456 || orf19.3197 || PAP1 || || Poly(A) polymerase, likely involved in mRNA polyadenylation; PAP is inhibited by parnafungin antifungals; non-sex gene located within the MTLa mating-type-like locus || 1 -0.69 -0.68 -0.68 -0.92 -0.18 -0.11 0.29 0.28 0.07 0.01 0.79 0.66 -0.03 0.14 0.22 0.37
13457 || orf19.5065 || ERD1 || || Putative membrane protein required for the retention of lumenal endoplasmic reticulum proteins; rat catheter biofilm induced || 1 -0.90 -1.21 -1.60 -1.56 -0.45 -0.55 0.04 0.16 0.13 -0.12 1.03 0.85 0.31 0.16 0.34 0.61
13458 || orf19.6822 || || || Ortholog(s) have NEDD8 ligase activity, ubiquitin binding activity and role in positive regulation of ubiquitin-protein ligase activity, protein neddylation || 1 -1.10 -1.02 -1.32 -1.39 -0.19 -0.44 -0.05 0.24 -0.26 -0.03 1.04 0.74 -0.21 0.32 0.67 0.12
13459 || orf19.4194 || || || Putative TFIIH complex subunit; possibly an essential gene, disruptants not obtained by UAU1 method || 1 -0.85 -0.81 -1.08 -1.24 -0.04 -0.26 0.07 0.16 -0.00 0.13 0.43 0.41 -0.38 0.15 0.52 -0.06
13460 || orf19.458 || || || Ortholog(s) have protein transmembrane transporter activity and role in chaperone-mediated protein complex assembly, mitochondrial respiratory chain complex III assembly, protein insertion into mitochondrial membrane from inner side || 1 -1.36 -1.50 -1.89 -2.03 -0.16 -0.47 0.32 0.26 0.21 0.14 0.74 0.34 -0.27 0.35 0.48 0.51
13461 || orf19.458 || || || Ortholog(s) have protein transmembrane transporter activity and role in chaperone-mediated protein complex assembly, mitochondrial respiratory chain complex III assembly, protein insertion into mitochondrial membrane from inner side || 1 -1.79 -1.60 -1.76 -1.79 -0.34 -0.35 0.16 0.27 0.25 0.22 0.55 0.60 -0.26 0.10 0.27 0.21
13462 || orf19.2102 || CKB1 || || Regulatory subunit of protein kinase CK2 (casein kinase II), beta subunit; null mutants are hypersensitive to caspofungin and hydrogen peroxide medium || 1 -0.87 -1.02 -1.08 -1.06 -0.43 -0.21 0.06 0.04 -0.34 0.20 0.53 0.31 -0.24 -0.12 0.25 0.31
13463 || orf19.1544 || || || Putative cis-golgi localized protein involved in ER to Golgi transport; Spider biofilm repressed || 1 -1.14 -1.06 -1.85 -1.81 0.14 -0.30 0.22 0.36 -0.49 -0.34 1.14 0.33 -0.41 -0.45 0.56 0.59
13464 || orf19.3055 || MED17 || || Putative RNA polymerase II mediator complex subunit; possibly an essential gene, disruptants not obtained by UAU1 method || 1 -1.26 -0.99 -1.24 -1.25 -0.45 -0.86 0.02 0.03 -0.24 0.25 0.62 0.02 -0.01 0.16 0.19 0.50
13465 || orf19.2369 || || || Ortholog(s) have ATP binding, DNA replication origin binding activity || 1 -1.01 -0.99 -1.53 -1.32 -0.61 -0.73 -0.18 0.00 -0.20 -0.20 0.13 -0.01 -0.03 0.38 0.41 0.20
13466 || orf19.6966 || || || Ortholog(s) have choline kinase activity, ethanolamine kinase activity, role in phosphatidylcholine biosynthetic process, phosphatidylethanolamine biosynthetic process and cytosol, nucleus localization || 1 -1.96 -2.01 -2.19 -2.04 -0.97 -0.87 -0.33 -0.25 -0.55 -0.06 0.50 0.64 0.55 0.64 0.47 0.34
13467 || orf19.7239 || MDG1 || || Ortholog(s) have role in pheromone-dependent signal transduction involved in conjugation with cellular fusion and cytoplasm, membrane raft, nucleus, plasma membrane localization || 1 -1.12 -1.36 -1.39 -0.99 -0.71 -0.30 -0.29 -0.10 -0.44 -0.27 0.04 0.12 0.34 0.11 0.41 0.28
13468 || orf19.4960 || || || Ortholog(s) have spermine synthase activity, role in pantothenate biosynthetic process, spermine biosynthetic process and cytoplasm localization || 1 -2.23 -2.61 -2.78 -2.77 -0.55 -0.50 0.06 -0.06 -0.27 0.14 0.69 0.92 0.88 0.44 1.09 0.89
13469 || orf19.4960 || || || Ortholog(s) have spermine synthase activity, role in pantothenate biosynthetic process, spermine biosynthetic process and cytoplasm localization || 1 -1.82 -1.82 -2.09 -2.66 -0.47 -0.63 -0.01 -0.11 -0.35 0.26 0.57 0.64 0.71 0.37 1.05 0.70
13470 || orf19.7558 || YTA6 || || Protein similar to S. cerevisiae Yta6p ATPase but ortholog of S. cervisiae Sap1; transposon mutation affects filamentous growth; induced by Mnl1 under weak acid stress || 1 -0.78 -0.77 -0.96 -1.12 -0.32 -0.13 0.03 -0.19 0.14 -0.03 0.20 0.36 -0.04 -0.34 0.40 0.22
13471 || orf19.6822 || || || Ortholog(s) have NEDD8 ligase activity, ubiquitin binding activity and role in positive regulation of ubiquitin-protein ligase activity, protein neddylation || 1 -0.92 -0.81 -0.70 -1.35 -0.36 -0.45 -0.21 0.02 -0.12 0.00 0.63 0.66 0.12 0.41 0.28 0.16
13472 || orf19.3026 || MAS1 || || Putative mitochondrial processing protease; Hap43-repressed; transcript regulated by Nrg1; oxidative stress-induced via Cap1 || 1 -0.88 -0.92 -0.98 -1.18 -0.04 -0.15 0.03 0.14 0.10 0.30 0.66 0.51 -0.72 -0.46 0.08 -0.20
13473 || orf19.7410 || CYM1 || || Putative metalloprotease of the mitochondrial intermembrane space; rat catheter biofilm induced || 1 -0.59 -0.45 -0.79 -0.86 -0.14 0.00 -0.09 -0.11 -0.27 0.23 0.36 0.43 -0.69 -0.51 0.41 0.27
13474 || orf19.6515 || HSP90 || || Essential chaperone, regulates several signal transduction pathways and temperature-induced morphogenesis; activated by heat shock, stress; localizes to surface of hyphae, not yeast cells; mediates echinocandin and biofilm azole resistance || 1 -0.41 -0.58 -0.97 -0.86 0.09 0.03 -0.11 0.00 -0.37 -0.16 0.35 0.07 -0.66 -0.35 0.26 -0.05
13475 || orf19.7144 || || || Ortholog(s) have GTPase activity, ribosome binding activity, role in nonfunctional rRNA decay, nuclear-transcribed mRNA catabolic process, no-go decay, ribosome disassembly and cytosol localization || 1 -0.87 -1.01 -1.21 -1.10 0.09 -0.18 -0.28 -0.05 -0.37 -0.21 0.74 0.42 -1.02 -0.28 0.31 0.26
13476 || orf19.4005 || || || Putative dephospho-CoA kinase; protein likely to be essential for growth, based on an insertional mutagenesis strategy || 1 -0.39 -0.53 -0.96 -0.63 0.23 -0.39 0.02 0.04 -0.04 -0.18 0.43 0.32 -0.67 -0.22 0.04 0.25
13477 || orf19.3722 || || || Predicted protein of rapamycin resistance; Spider biofilm induced || 1 -1.25 -1.31 -1.68 -1.13 -0.69 -0.71 0.47 -0.15 -0.10 -0.14 0.53 0.51 -0.96 -0.41 0.33 -0.03
13478 || orf19.6757 || GCY1 || || Aldo/keto reductase; mutation confers hypersensitivity to toxic ergosterol analog; farnesol-repressed; stationary phase enriched protein; flow model biofilm induced; Spider biofilm repressed || 1 -1.28 -0.95 -1.13 -1.30 -0.57 -0.29 0.06 -0.15 -0.21 -0.66 0.87 0.69 -0.86 -0.56 0.39 0.00
13479 || orf19.268 || || || Ortholog(s) have role in transcription-coupled nucleotide-excision repair and Ddb1-Ckn1 complex, cytosol localization || 1 -1.65 -2.00 -1.34 -1.57 -0.18 -0.28 -0.12 -0.10 0.11 -0.72 0.92 0.85 -1.01 -0.14 0.66 0.75
13480 || orf19.6729 || TIP120 || || Protein similar to human CAND1 (Cullin-Associated Nedd8-Dissociated) protein involved in regulation of SCF complexes; binds unnedddylated cullin Cdc53; mutants are viable || 1 -0.34 -0.44 -0.60 -0.62 -0.09 -0.26 0.08 -0.14 -0.03 -0.18 0.28 0.37 -0.39 0.07 0.09 0.42
13481 || orf19.1745 || || || Protein of unknown function; Hap43-repressed gene || 1 -0.60 -0.88 -1.07 -0.72 -0.32 -0.35 -0.00 0.02 0.11 -0.22 0.27 0.80 -0.79 -0.20 0.01 0.83
13482 || orf19.5239 || || || Predicted alanine-tRNA ligase; oxidative stress-induced via Cap1 || 1 -1.30 -1.22 -1.43 -1.55 -1.13 -0.55 0.22 0.05 0.22 0.12 1.10 1.27 -1.27 -0.47 0.85 1.02
13483 || orf19.7152 || || || Protein similar to Aspergillus CYSK O-acetylserine sulfhydrylase, suggesting that C. albicans uses an O-acetyl-serine (OAS) pathway of sulfur assimilation; upregulated in biofilm; protein level decreases in stationary phase cultures || 1 -0.55 -0.61 -0.76 -0.30 0.11 -0.07 0.04 0.14 -0.16 -0.03 0.39 0.58 -0.62 -0.32 0.40 0.48
13484 || orf19.6757 || GCY1 || || Aldo/keto reductase; mutation confers hypersensitivity to toxic ergosterol analog; farnesol-repressed; stationary phase enriched protein; flow model biofilm induced; Spider biofilm repressed || 1 -0.43 -0.55 -1.04 -1.30 -0.36 -0.30 0.17 -0.04 -0.32 -0.74 1.02 0.64 -0.65 -0.51 0.42 0.34
13485 || orf19.1083 || || || Putative protein of unknown function; macrophage-induced gene || 1 -0.41 -0.28 -0.84 -0.90 0.04 0.10 0.39 0.57 -0.29 0.67 0.90 0.38 -0.72 0.23 0.19 0.51
13486 || orf19.3244 || || || Ortholog(s) have role in mitochondrial respiratory chain complex assembly and mitochondrion localization || 1 -0.47 -0.31 -1.08 -1.13 0.30 -0.13 0.36 0.38 0.16 0.59 0.78 0.35 -0.31 0.19 0.15 0.49
13487 || orf19.1378 || SUP35 || || Translation factor eRF3; shows prion-like aggregation in some, not all, studies; partially complements S. cerevisiae sup35 mutant translation defect; species barrier with S. cerevisiae Sup35p prion; gene not regulated by yeast-hyphal switch || 1 -0.62 -0.52 -1.46 -1.51 0.05 -0.28 0.23 0.38 -0.42 0.16 0.94 0.30 -0.33 -0.01 -0.14 0.44
13488 || orf19.3914 || || || Has domain(s) with predicted translation initiation factor activity, role in translational initiation and cytoplasm localization || 1 -0.46 -0.46 -1.02 -1.37 0.40 0.41 0.44 0.10 -0.21 -0.05 0.59 0.67 0.43 0.00 0.64 0.12
13489 || orf19.240 || PAM17 || || Predicted component of the presequence translocase-associated import motor (PAM complex) involved in protein import into mitochondrial matrix || 1 -0.37 -0.45 -1.20 -1.25 0.51 0.22 0.33 0.40 -0.28 -0.23 0.59 0.39 0.30 -0.16 0.38 0.17
13490 || orf19.2476 || || || Ortholog(s) have histone demethylase activity (H3-trimethyl-K4 specific) activity || 1 -0.34 -0.22 -1.05 -0.72 0.24 -0.25 0.36 0.28 -0.05 0.01 0.30 0.30 -0.06 0.42 0.62 0.14
13491 || orf19.2557 || SEC65 || || Component of the protein-targeting Signal Recognition Particle (SRP); similar to mammalian Srp19; functional homolog of S. cerevisiae Sec65; Tbf1-induced || 1 -0.30 -0.17 -0.79 -0.58 0.22 -0.18 0.16 0.28 -0.42 0.40 0.50 0.02 0.06 0.11 0.65 0.10
13492 || orf19.1706 || MET18 || || Putative protein with a predicted role in nucleotide excision repair (NER) and RNA polymerase II (RNAP II) transcription; Plc1p-regulated || 1 -0.44 -0.17 -1.40 -1.33 0.51 -0.69 0.38 0.38 -0.51 0.45 0.77 0.07 0.25 0.18 0.73 0.03
13493 || orf19.1698 || || || Ortholog(s) have phosphatidate phosphatase activity, role in actin cytoskeleton organization, cellular lipid metabolic process and actin cortical patch localization || 1 -0.97 -0.50 -1.44 -1.40 0.36 -0.63 0.28 0.20 -0.39 0.27 0.58 0.22 -0.22 0.09 0.88 0.50
13494 || orf19.6912 || || || Putative ethanolamine kinase || 1 -0.31 -0.14 -0.58 -1.16 0.30 -0.26 0.45 0.51 0.06 0.44 0.67 0.37 0.14 -0.01 0.62 0.50
13495 || orf19.3022 || || || Ortholog(s) have structural constituent of ribosome activity and mitochondrial small ribosomal subunit localization || 1 -0.43 -0.47 -1.25 -1.57 0.59 0.03 0.65 0.71 0.16 0.41 1.02 0.67 0.19 -0.08 1.12 0.46
13496 || orf19.3272 || || || Ortholog(s) have chaperone binding activity, role in box C/D snoRNP assembly, protein folding and R2TP complex, cytoplasm, nucleus localization || 1 -0.15 -0.21 -1.03 -0.97 0.42 0.00 0.51 0.33 -0.08 0.06 0.55 0.37 0.33 0.19 0.85 0.28
13497 || orf19.6062 || || || Putative TIM23 translocase complex subunit; membrane-localized; Hap43-repressed || 1 -0.21 -0.19 -1.04 -1.04 0.50 -0.02 0.63 0.61 0.14 0.15 0.84 0.47 -0.28 0.08 0.56 0.18
13498 || orf19.3022 || || || Ortholog(s) have structural constituent of ribosome activity and mitochondrial small ribosomal subunit localization || 1 -0.60 -0.46 -1.43 -1.67 0.66 -0.17 0.75 0.70 0.12 0.41 1.09 0.07 0.32 -0.13 0.97 0.05
13499 || orf19.3064 || MRPL27 || || Putative 60S ribosomal protein L27, mitochondrial precursor || 1 -0.77 -0.77 -1.86 -1.91 0.29 -0.22 1.03 1.42 -0.05 0.52 1.66 -0.11 0.46 -0.21 0.74 -0.02
13500 || orf19.7667 || IAH1 || || Protein similar to S. cerevisiae Iah1p, which is involved in acetate metabolism; mutation confers hypersensitivity to tunicamycin; transposon mutation affects filamentous growth || 1 -0.36 -0.28 -0.68 -0.58 0.28 0.04 0.32 0.49 -0.13 -0.01 0.63 0.14 -0.18 -0.25 0.50 0.25
13501 || orf19.1531 || || || Ortholog(s) have RNA binding, protein heterodimerization activity, role in mRNA cleavage, mRNA polyadenylation and cytosol, mRNA cleavage factor complex, mitochondrion localization || 1 -0.65 -0.26 -1.54 -1.15 -0.10 -0.61 0.26 0.63 -0.08 0.04 1.03 0.87 -0.06 -0.00 0.92 0.05
13502 || orf19.1058 || || || Ortholog(s) have ubiquitin binding activity, role in ubiquitin-dependent protein catabolic process and proteasome regulatory particle, lid subcomplex, proteasome storage granule localization || 1 -0.13 -0.19 -1.24 -1.00 0.07 -0.35 0.28 0.62 -0.37 0.01 0.90 0.41 0.19 0.02 0.80 0.50
13503 || orf19.3294 || MBF1 || || Putative transcriptional coactivator; caspofungin repressed || 1 -0.43 -0.45 -1.56 -1.55 0.06 -0.40 0.80 0.65 -0.14 -0.41 1.47 0.44 -0.31 0.08 1.36 0.75
13504 || orf19.3006 || GGA2 || || Protein involved in Golgi trafficking; rat catheter and Spider biofilm repressed || 1 -0.17 -0.40 -0.64 -0.52 0.04 -0.33 0.10 0.27 -0.12 -0.15 0.86 0.31 0.05 0.08 0.32 0.27
13505 || orf19.1750 || SLR1 || || Protein similar to mammalian SR-like RNA splicing factor; involved in filamentous growth and virulence; gene has intron; Spider biofilm repressed || 1 -0.60 -0.63 -0.94 -0.66 0.68 -0.26 0.32 0.31 -0.15 -0.11 1.05 0.23 0.08 0.08 0.39 0.43
13506 || orf19.1095 || GLE2 || || Putative nuclear pore complex; possibly an essential gene, disruptants not obtained by UAU1 method; rat catheter biofilm repressed || 1 -0.03 -0.25 -0.70 -0.73 0.11 -0.14 0.25 0.39 -0.23 -0.23 0.55 0.05 0.27 0.14 0.13 0.22
13507 || orf19.5630 || APA2 || || Putative ATP adenylyltransferase II; regulated by Gcn4; repressed by amino acid starvation (3-AT); induced by prostaglandins; Hap43-repressed; Spider biofilm repressed || 1 -0.08 -0.25 -1.67 -1.74 0.39 -0.15 1.05 1.17 0.10 -0.25 1.56 0.23 0.96 -0.08 0.55 0.70
13508 || orf19.3796 || DCR1 || || Putative Dicer RNAse involved in RNA interference, similar to S. cerevisiae Rnt1p but orthologous to S. castellii Dcr1p, which is not conserved in S. cerevisiae || 1 -0.57 -0.68 -1.40 -1.62 0.01 -0.23 0.88 0.82 0.20 0.14 1.26 0.17 0.43 0.19 0.26 0.91
13509 || orf19.5408 || HRK1 || || Putative serine/threonine kinase; predicted role in cellular ion homeostasis; Spider biofilm repressed || 1 -0.64 -0.71 -1.34 -1.70 0.10 -0.02 1.10 0.70 0.73 -0.26 1.29 0.34 0.45 0.52 0.65 0.70
13510 || orf19.5408 || HRK1 || || Putative serine/threonine kinase; predicted role in cellular ion homeostasis; Spider biofilm repressed || 1 -0.45 -0.58 -1.27 -1.52 0.43 0.11 1.33 0.79 0.55 -0.25 1.21 0.55 0.54 0.35 0.88 1.21
13511 || orf19.5527 || || || Protein with a predicted role in 5.8S rRNA processing; flow model biofilm induced || 1 -0.55 -0.56 -0.91 -1.17 0.05 -0.15 0.78 0.66 0.24 -0.73 1.15 0.46 0.72 0.17 0.07 0.83
13512 || orf19.5527 || || || Protein with a predicted role in 5.8S rRNA processing; flow model biofilm induced || 1 -0.92 -0.59 -1.08 -1.41 -0.22 -0.25 0.76 0.47 -0.02 -0.61 0.89 0.34 0.33 -0.04 0.00 0.98
13513 || orf19.4580 || || || Protein of unknown function; Hap43-repressed gene || 1 -0.60 -0.89 -1.56 -1.64 0.72 0.19 0.99 0.59 0.37 -0.87 1.85 0.76 0.53 -0.54 0.46 1.34
13514 || orf19.1200 || || || Protein of unknown function; Spider biofilm induced || 1 -0.42 -0.70 -0.85 -0.81 0.49 -0.34 0.64 0.54 0.69 -0.11 1.20 0.20 0.29 0.34 0.22 0.98
13515 || orf19.5282 || || || Protein of unknown function; Hap43-repressed gene; mRNA binds to She3; repressed in hyphae; Efg1 and Efh1 regulated; 5'-UTR intron; induced by Mnl1 under weak acid stress; rat catheter biofilm induced || 1 -0.51 -0.40 -1.39 -1.53 0.21 -0.91 1.20 0.33 0.90 0.07 1.59 0.01 -0.05 0.10 0.31 1.13
13516 || orf19.5282 || || || Protein of unknown function; Hap43-repressed gene; mRNA binds to She3; repressed in hyphae; Efg1 and Efh1 regulated; 5'-UTR intron; induced by Mnl1 under weak acid stress; rat catheter biofilm induced || 1 -0.56 -0.58 -1.47 -1.69 -0.09 -0.95 0.85 0.35 0.84 -0.10 1.40 0.35 -0.29 -0.01 0.33 1.18
13517 || orf19.2196 || || || Ortholog(s) have ubiquitin binding activity and cytoplasm localization || 1 -0.96 -0.54 -1.31 -1.35 -0.05 -0.44 1.15 0.23 0.74 -0.03 0.85 0.57 -0.14 0.41 0.56 0.43
13518 || orf19.835 || || || Ortholog(s) have role in nucleosome mobilization and Ino80 complex, cytosol localization || 1 -0.27 -0.37 -0.42 -0.68 0.02 0.14 0.35 0.33 0.34 -0.16 0.74 0.59 -0.06 0.19 0.04 0.83
13519 || orf19.4478 || || || Ortholog(s) have aspartate-tRNA ligase activity, role in mitochondrial aspartyl-tRNA aminoacylation and mitochondrion localization || 1 -0.26 -0.26 -0.30 -0.73 0.17 0.00 0.20 0.09 0.29 -0.09 0.31 0.27 0.20 0.07 0.05 0.68
13520 || orf19.4245 || || || Protein with a predicted pleckstrin domain; Hap43-repressed gene || 1 -0.23 -0.17 -1.48 -1.89 -0.21 -0.98 0.44 0.44 0.40 0.57 1.12 0.61 0.87 0.42 0.16 0.68
13521 || orf19.7376 || || || Ortholog of C. dubliniensis CD36 : Cd36_85880, C. parapsilosis CDC317 : CPAR2_806870, Candida tenuis NRRL Y-1498 : CANTEDRAFT_96983 and Debaryomyces hansenii CBS767 : DEHA2D16148g || 1 -0.92 -0.75 -0.71 -0.75 -0.02 -0.14 0.45 -0.16 0.35 0.43 0.28 0.86 0.78 0.22 0.90 0.41
13522 || orf19.932 || || || Putative aminophospholipid translocase (flippase); merged with orf19.2226 in Assembly 21; possibly an essential gene, disruptants not obtained by UAU1 method || 1 -0.90 -0.57 -0.51 -0.46 0.19 0.04 0.05 -0.17 -0.20 -0.01 0.63 0.49 0.43 0.07 0.53 0.45
13523 || orf19.7239 || MDG1 || || Ortholog(s) have role in pheromone-dependent signal transduction involved in conjugation with cellular fusion and cytoplasm, membrane raft, nucleus, plasma membrane localization || 1 -1.01 -1.02 -1.00 -0.63 -0.37 0.00 0.06 0.20 -0.38 -0.14 0.49 0.52 0.70 0.16 0.65 0.46
13524 || orf19.4502 || || || Ortholog(s) have ATPase activity, DNA binding, TBP-class protein binding activity || 1 -1.03 -0.97 -0.78 -0.80 -0.16 -0.47 0.17 0.41 0.08 -0.07 0.63 0.26 0.09 0.48 0.25 0.87
13525 || orf19.3018 || SPP1 || || Putative histone methyltransferase; induced by nitric oxide independent of Yhb1p; cell-cycle regulated periodic mRNA expression || 1 -0.52 -0.35 -0.36 -0.40 -0.16 -0.47 -0.06 0.09 -0.21 0.27 0.44 0.18 0.25 0.25 0.40 0.38
13526 || orf19.2054 || FGR15 || || Putative transcription factor with zinc finger DNA-binding motif; lacks an ortholog in S. cerevisiae; transposon mutation affects filamentous growth; caspofungin induced; mutation causes marginal increase in caspofungin sensitivity || 1 -1.01 -0.83 -0.42 -0.68 -0.24 -0.37 0.22 0.20 0.28 0.64 0.79 0.26 0.16 0.35 0.64 0.00
13527 || orf19.6665 || || || Ortholog(s) have Ran GTPase binding, nucleocytoplasmic transporter activity || 1 -0.40 -0.40 -0.41 -0.89 0.21 -0.16 -0.07 0.29 -0.22 0.22 0.62 0.33 0.38 -0.05 0.32 0.38
13528 || orf19.3026 || MAS1 || || Putative mitochondrial processing protease; Hap43-repressed; transcript regulated by Nrg1; oxidative stress-induced via Cap1 || 1 -0.23 -0.27 -0.47 -0.77 0.12 -0.26 -0.07 0.00 -0.10 0.16 0.33 0.41 -0.11 -0.29 0.06 0.31
13529 || orf19.3203 || RCY1 || || Putative F-box protein involved in endocytic membrane traffic and/or recycling; fungal-specific (no human or murine homolog) || 1 -0.13 -0.37 -0.95 -1.25 0.15 -0.46 0.12 -0.20 -0.63 -0.16 0.14 0.14 0.43 -0.14 0.39 -0.70
13530 || orf19.5576 || || || Putative pantothenate kinase; ortholog of S. cerevisiae Cab1; transposon mutation affects filamentous growth; repressed in core stress response || 1 -0.35 -0.50 -0.94 -1.32 0.17 -0.29 0.09 -0.26 -0.45 0.03 -0.00 -0.20 0.40 0.20 0.45 -0.28
13531 || orf19.3333 || || || Ortholog(s) have poly(A) RNA binding activity, role in mRNA polyadenylation, poly(A)+ mRNA export from nucleus, regulation of mRNA stability and cytoplasm, nucleus localization || 1 -0.42 -0.44 -1.04 -0.87 -0.06 -0.43 0.02 0.17 -0.79 0.26 0.31 -0.15 0.06 0.14 0.54 -0.22
13532 || orf19.3480 || || || Ortholog(s) have structural constituent of ribosome activity and mitochondrial small ribosomal subunit localization || 1 -0.49 -0.52 -1.56 -1.67 0.32 -0.65 0.27 0.15 -0.61 0.73 0.19 0.22 -0.09 -0.29 0.65 -0.53
13533 || orf19.5973 || PHB2 || || Prohibitin 2; plasma membrane localized || 1 -0.24 -0.29 -0.99 -1.21 0.34 -0.19 0.14 0.28 -0.11 -0.05 0.08 -0.19 -0.31 0.12 0.33 -0.25
13534 || orf19.5924 || ZCF31 || || Zn(II)2Cys6 transcription factor of unknown function; mutant is sensitive to copper and SDS, and resistant to Calcofluor White; required for yeast cell adherence to silicone substrate || 1 -0.47 -0.43 -1.65 -1.56 0.34 -0.13 0.68 -0.13 -0.31 -0.44 0.11 0.52 0.13 -0.36 0.29 0.37
13535 || orf19.3528 || || || Protein of unknown function; Spider biofilm induced || 1 -0.06 0.03 -1.02 -1.62 0.48 0.18 0.20 0.18 -0.59 0.01 0.16 -0.12 0.22 -0.51 0.73 -0.17
13536 || orf19.1492 || PRP39 || || Putative component of the U1 snRNP; involved in splicing; Hap43-induced gene; Spider biofilm induced || 1 -0.43 -0.50 -1.85 -1.79 0.38 0.14 -0.05 -0.19 -0.59 0.28 0.64 0.51 0.24 -0.87 0.84 0.08
13537 || orf19.684 || || || Putative transcription factor with zinc finger DNA-binding motif; heterozygous null mutant exhibits hypersensitivity to parnafungin and cordycepin in the C. albicans fitness test || 1 -0.37 -0.34 -0.81 -0.94 0.42 0.01 -0.07 -0.05 -0.14 -0.31 0.57 0.17 0.10 0.08 0.31 0.02
13538 || orf19.1214 || || || Ortholog(s) have metalloaminopeptidase activity, role in protein initiator methionine removal involved in protein maturation and cytosol, nucleus localization || 1 -0.80 -0.67 -1.74 -1.99 0.47 -0.04 0.21 -0.12 -1.20 -0.52 1.04 -0.17 -0.23 -0.03 0.67 0.31
13539 || orf19.2640 || FUR1 || || Uracil phosphoribosyltransferase; predicted tetrameric enzyme of pyrimidine salvage; mutations associated with flucytosine resistance in clade I clinical isolates; flucytosine, macrophage-induced protein; levels decrease in stationary phase || 1 -0.29 -0.15 -0.88 -1.06 0.40 -0.02 0.28 0.07 -0.27 -0.12 0.94 0.12 -0.01 -0.37 -0.07 0.32
13540 || orf19.2002 || || || Ortholog(s) have structural constituent of nuclear pore activity and role in nuclear pore organization, poly(A)+ mRNA export from nucleus, protein import into nucleus, ribosomal large subunit export from nucleus || 1 -0.00 0.14 -0.90 -0.80 0.29 -0.21 0.14 0.09 -0.40 -0.03 0.63 0.18 -0.08 0.08 0.05 0.11
13541 || orf19.808 || || || Ortholog(s) have role in histone deacetylation, negative regulation of chromatin silencing at rDNA and negative regulation of chromatin silencing at silent mating-type cassette, more || 1 -0.25 -0.25 -0.48 -0.46 -0.06 -0.16 0.05 0.17 -0.38 -0.34 0.17 0.01 -0.22 -0.12 0.09 0.03
13542 || orf19.1677 || || || Protein of unknown function; transcript detected on high-resolution tiling arrays || 1 -0.87 -0.85 -1.52 -1.76 -0.26 -1.18 0.02 0.32 -0.54 -0.73 0.57 -0.32 -0.40 -0.84 0.00 -0.20
13543 || orf19.131.2 || || || Ortholog(s) have endoplasmic reticulum localization || 1 -0.21 -0.11 -0.83 -0.91 -0.06 -0.31 -0.01 0.26 -0.51 -0.28 0.18 -0.25 -0.44 -0.20 -0.25 -0.11
13544 || orf19.3697 || || || Ortholog(s) have role in ascospore formation, re-entry into mitotic cell cycle after pheromone arrest, regulation of meiosis I, regulation of mitosis and sporocarp development involved in sexual reproduction, more || 1 -0.05 -0.24 -1.74 -2.61 -0.13 -0.98 0.23 0.31 -0.32 -0.31 0.50 0.03 -0.10 -0.53 0.12 0.67
13545 || orf19.3697 || || || Ortholog(s) have role in ascospore formation, re-entry into mitotic cell cycle after pheromone arrest, regulation of meiosis I, regulation of mitosis and sporocarp development involved in sexual reproduction, more || 1 -0.36 -0.41 -2.60 -1.49 -0.19 -1.23 0.14 0.06 -0.40 -0.44 0.43 0.15 -0.06 0.01 0.18 0.43
13546 || orf19.5274 || || || Ortholog(s) have cellular bud neck, cellular bud tip, cytoplasm localization || 1 -0.22 -0.34 -1.30 -0.84 -0.26 -0.49 -0.01 0.30 -0.54 -0.45 0.38 -0.16 -0.24 -0.25 0.29 0.50
13547 || orf19.26 || || || Putative peptide N-glycanase; induced by nitric oxide independent of Yhb1p || 1 -0.29 -0.22 -0.86 -1.00 -0.25 -0.49 0.11 0.15 -0.21 -0.13 0.20 -0.03 -0.44 -0.28 0.60 0.51
13548 || orf19.1474 || SLA1 || || Protein required for assembly of the cortical actin cytoskeleton; contains three SH3 domains; transcription is regulated by Nrg1 and Mig1; flow model biofilm repressed || 1 -0.20 -0.22 -1.10 -1.11 0.40 -0.29 0.58 0.29 -0.30 -0.82 0.34 -0.19 0.12 -0.36 0.47 0.06
13549 || orf19.3480 || || || Ortholog(s) have structural constituent of ribosome activity and mitochondrial small ribosomal subunit localization || 1 -0.79 -0.37 -1.10 -0.95 0.27 -0.36 0.22 0.50 -0.28 0.75 -0.16 0.38 0.21 -0.19 0.59 0.01
13550 || orf19.6141 || HGT16 || || Putative glucose transporter of the major facilitator superfamily; the C. albicans glucose transporter family comprises 20 members; 12 probable membrane-spanning segments; gene has intron; expressed in rich medium with 2% glucose || 1 -0.68 -0.94 -0.87 -1.49 -0.26 -0.24 0.11 0.88 -0.04 0.86 0.31 -0.48 -0.25 -0.25 0.93 -0.27
13551 || orf19.1300 || || || Putative mitochondrial membrane protein; homozygous transposon insertion causes decreased colony wrinkling under filamentous growth-inducing conditions, but does not block true hyphal formation in liquid media || 1 -0.46 -0.44 -0.56 -0.64 -0.18 -0.32 0.13 0.23 0.28 0.63 -0.13 0.22 -0.33 -0.30 0.55 -0.54
13552 || orf19.6847 || || || Putative tRNA U44 2'-O-methyltransferase; virulence-group-correlated expression; induced during oral infection; mutants have reduced ability to damage oral epithelial cells; early-stage flow model biofilm induced || 1 -0.13 -0.42 -0.48 -1.04 -0.35 -0.16 0.01 -0.39 0.37 0.25 -0.09 0.23 0.04 -0.16 0.21 0.36
13553 || orf19.342 || BMT7 || || Beta-mannosyltransferase, member of a 9-gene family that includes characterized genes BMT1, BMT2, BMT3, and BMT4 with roles in beta-1,2-mannosylation of cell wall phosphopeptidomannan; downregulated in azole-resistant strain; Hap43p-induced || 1 -1.10 -1.03 -1.36 -2.37 -0.59 -0.86 -0.11 -0.01 0.87 0.05 -0.36 0.86 -0.23 0.09 0.82 0.45
13554 || orf19.4235 || PDE1 || || Low affinity cyclic nucleotide phosphodiesterase; mediates cAMP signaling in response to glucose or intracellular acidification; macrophage-repressed; Spider biofilm induced || 1 -1.26 -1.23 -0.80 -1.33 -0.50 0.45 0.19 -0.36 0.56 -0.03 -0.45 0.41 -0.12 0.41 0.68 0.12
13555 || orf19.2137 || || || Ortholog(s) have mitochondrion localization || 1 -1.26 -1.30 -0.86 -1.28 -0.31 0.03 0.49 -0.19 0.62 -0.40 -0.28 -0.15 -0.16 -0.04 -0.04 0.30
13556 || orf19.4771 || || || Protein of unknown function; Spider biofilm induced || 1 -2.37 -3.04 -1.84 -2.36 -1.27 -0.34 0.94 -0.25 0.62 -0.96 0.22 0.59 0.33 0.45 0.26 0.70
13557 || orf19.1614 || MEP1 || || Ammonium permease; Mep1 more efficient permease than Mep2, Mep2 has additional regulatory role; 11 predicted transmembrane regions; low mRNA abundance; hyphal downregulated; flow model biofilm induced || 1 -1.52 -1.88 -1.64 -1.40 -1.23 -0.51 0.01 -0.43 0.52 -0.31 0.11 0.26 0.42 -0.36 1.44 1.02
13558 || orf19.6884 || GWT1 || || Inositol acyltransferase with role in early steps of GPI anchor biosynthetic process; antifungal drug target || 1 -0.76 -0.80 -0.57 -0.31 -0.58 -0.46 0.02 -0.08 0.25 0.10 -0.14 0.22 -0.13 -0.07 0.15 0.32
13559 || orf19.6316 || || || Predicted membrane transporter, member of the L-amino acid transporter-3 (LAT3) family, major facilitator superfamily (MFS) || 1 -0.84 -1.39 -1.28 -0.78 -0.71 -0.75 -0.15 -0.22 -0.11 -0.42 0.30 1.09 -0.36 -0.19 0.89 0.43
13560 || orf19.4221 || ORC4 || || Phosphorylated protein similar to S. cerevisiae Orc4, subunit of the origin recognition complex (ORC); induced by alpha pheromone in SpiderM medium || 1 -0.59 -0.89 -0.69 -0.76 -0.03 -0.25 -0.24 -0.11 0.06 0.11 -0.09 0.77 -0.14 -0.20 0.17 0.12
13561 || orf19.3450.1 || || || Ortholog of C. dubliniensis CD36 : Cd36_61450, C. parapsilosis CDC317 : CPAR2_602710, Candida tenuis NRRL Y-1498 : cten_CGOB_00240 and Pichia stipitis Pignal : psti_CGOB_00191 || 1 -0.95 -1.03 -0.96 -1.15 -0.33 -0.06 -0.04 0.16 0.07 -0.59 0.08 1.09 0.17 -0.04 0.59 0.70
13562 || orf19.4010 || PAN3 || || Ortholog(s) have poly(A)-specific ribonuclease activity, role in mRNA 3'-end processing, postreplication repair and PAN complex, cytosol, nucleus localization || 1 -0.82 -0.71 -0.61 -0.68 0.02 -0.12 0.02 0.18 0.12 -0.25 0.46 0.68 0.19 -0.32 0.20 0.17
13563 || orf19.6377 || || || Ortholog(s) have protein C-terminal leucine carboxyl O-methyltransferase activity, role in C-terminal protein methylation, cellular protein complex assembly and mitochondrion localization || 1 -1.21 -1.02 -0.71 -0.57 0.09 -0.38 0.27 0.27 0.18 0.25 0.07 0.22 -0.02 -0.08 0.52 -0.03
13564 || orf19.3573 || PEX6 || || Ortholog(s) have ATPase activity, protein heterodimerization activity, role in fatty acid metabolic process, protein import into peroxisome matrix, receptor recycling, replicative cell aging and cytosol, nucleus, peroxisome localization || 1 -1.53 -1.72 -1.46 -0.77 -0.36 -0.96 0.37 0.32 0.11 0.54 0.02 0.59 -0.50 0.04 0.40 -0.10
13565 || orf19.666 || || || Essential protein required for the DNA integrity checkpoint pathway; Spider biofilm induced || 1 -0.70 -0.81 -0.70 -0.54 0.50 0.34 -0.16 -0.05 0.64 0.06 0.06 0.71 -0.03 -0.16 0.41 0.06
13566 || orf19.1375 || LEU42 || || Putative alpha-isopropylmalate synthase; fungal-specific; induced by human blood or polymorphonuclear cells; regulated by Gcn2 and Gcn4; stationary phase enriched protein; Spider biofilm induced || 1 -1.53 -1.60 -1.35 -1.25 0.38 0.22 0.57 -0.30 0.85 -0.17 -0.30 0.51 -0.94 -0.39 0.65 -0.03
13567 || orf19.5780 || || || Putative protein of unknown function; Hap43p-repressed gene || 1 -0.70 -0.68 -0.54 -0.44 0.05 -0.02 -0.33 -0.26 0.44 -0.04 -0.18 0.42 -0.48 -0.32 0.22 0.05
13568 || orf19.666 || || || Essential protein required for the DNA integrity checkpoint pathway; Spider biofilm induced || 1 -0.89 -0.85 -0.67 -0.46 -0.01 0.05 -0.31 -0.42 0.23 0.00 -0.35 0.29 -0.31 -0.12 0.10 -0.10
13569 || orf19.578 || || || Ortholog(s) have Rab GTPase activator activity and role in actin filament organization, endocytosis, exocytosis, regulation of GTPase activity, regulation of protein localization || 1 -0.55 -0.75 -0.68 -0.82 -0.12 0.31 -0.17 -0.28 0.35 -0.29 -0.21 0.23 -0.18 -0.19 0.43 -0.50
13570 || orf19.4898 || || || Putative protein of unknown function; induced by prostaglandins || 1 -0.76 -0.36 -0.83 -1.06 0.16 0.73 0.10 -0.13 0.23 -0.74 -0.00 0.27 -0.00 -0.05 1.22 0.58
13571 || orf19.583 || || || Indoleamine 2,3-dioxygenase (IDO); rate-limiting enzyme of tryptophan catabolism via kynurenine; enzyme inhibition by 1-methyl-D,L-tryptophan increases hyphal growth; expressed in yeast and hyphae; rat catheter and Spider biofilm induced || 1 -0.36 -0.39 -0.50 -1.07 0.37 0.71 0.22 -0.27 -0.06 -0.59 0.22 -0.10 -0.06 0.03 0.60 0.40
13572 || orf19.223 || || || Putative serine/threonine protein kinase; Hap43-repressed; induced by prostaglandins; possibly an essential gene, disruptants not obtained by UAU1 method; flow model biofilm induced; Spider biofilm induced || 1 -0.40 -0.62 -1.09 -1.46 0.40 0.50 0.54 -0.26 -0.35 -1.31 0.76 -0.11 0.51 0.44 1.21 0.57
13573 || orf19.223 || || || Putative serine/threonine protein kinase; Hap43-repressed; induced by prostaglandins; possibly an essential gene, disruptants not obtained by UAU1 method; flow model biofilm induced; Spider biofilm induced || 1 -0.84 -0.59 -0.77 -1.05 -0.00 0.34 0.46 -0.21 -0.34 -1.07 0.44 0.28 0.19 0.41 0.80 1.07
13574 || orf19.2853 || || || Protein of unknown function; rat catheter biofilm induced || 1 -0.59 -0.72 -0.53 -0.60 0.36 0.40 0.33 0.27 -0.23 -0.66 0.54 0.16 0.08 0.05 0.74 0.61
13575 || orf19.5757 || || || Ortholog(s) have cytoplasm, nucleus localization || 1 -0.35 -0.40 -0.62 -0.79 0.12 0.33 0.21 0.25 -0.27 -0.34 0.44 0.25 0.23 -0.01 0.62 0.44
13576 || orf19.6590 || VMA22 || || Ortholog(s) have unfolded protein binding activity, role in vacuolar acidification, vacuolar proton-transporting V-type ATPase complex assembly and extrinsic to endoplasmic reticulum membrane localization || 1 -0.93 -0.48 -0.64 -0.95 0.39 0.69 0.50 0.16 0.22 0.23 0.88 0.42 0.38 0.28 0.22 0.90
13577 || orf19.3062 || || || Ortholog(s) have role in chromatin remodeling and ASTRA complex, mitochondrion localization || 1 -0.35 -0.34 -0.56 -0.83 0.58 0.20 0.24 -0.10 0.02 0.02 0.11 0.02 0.08 0.32 0.44 0.55
13578 || orf19.2788 || || || Has domain(s) with predicted RNA binding, pseudouridine synthase activity and role in pseudouridine synthesis || 1 -0.53 -0.64 -1.20 -1.07 0.06 0.13 0.14 0.50 0.21 0.36 0.19 0.29 -0.04 0.70 0.55 0.51
13579 || orf19.3888.2 || || || Dubious open reading frame || 1 -0.68 -0.89 -0.69 -1.33 -0.31 -0.03 -0.06 0.86 0.30 0.20 0.08 0.38 -0.29 0.27 0.70 0.50
13580 || orf19.5247 || || || Ortholog(s) have cytoplasm localization || 1 -0.73 -0.93 -0.55 -0.49 -0.05 0.16 0.14 0.02 -0.22 -0.22 -0.08 0.19 -0.14 0.25 0.59 0.54
13581 || orf19.4750 || || || Ortholog of C. dubliniensis CD36 : Cd36_08410, C. parapsilosis CDC317 : CPAR2_301700, Candida tenuis NRRL Y-1498 : cten_CGOB_00267 and Debaryomyces hansenii CBS767 : DEHA2C10560g || 1 -0.64 -0.57 -0.40 -0.84 0.07 0.02 0.17 -0.23 -0.05 0.04 -0.08 0.31 0.09 0.25 0.34 0.53
13582 || orf19.2980 || || || Ortholog(s) have ATP-dependent RNA helicase activity and role in generation of catalytic spliceosome for first transesterification step, spliceosomal complex disassembly || 1 -0.53 -0.40 -0.47 -0.41 0.20 0.11 0.01 -0.14 -0.11 0.01 -0.09 0.30 0.22 0.45 0.16 0.22
13583 || orf19.3628 || RSP5 || || Putative NEDD4 family E3 ubiquitin ligase; induced during infection of murine kidney, compared to growth in vitro; has murine homolog; possibly an essential gene, disruptants not obtained by UAU1 method || 1 -0.35 -0.50 -0.55 -0.32 0.17 0.48 -0.07 0.21 0.34 0.18 0.39 0.53 0.07 0.44 0.23 0.66
13584 || orf19.407 || GCD6 || || Ortholog of S. cerevisiae Gcd6; catalytic epsilon subunit of the translation initiation factor eIF2B; genes encoding translation factors are repressed by phagocytosis by murine macrophages || 1 -0.41 -0.52 -0.89 -0.71 0.08 0.31 0.11 0.25 0.14 0.47 0.58 0.56 -0.24 0.43 0.38 0.59
13585 || orf19.2788 || || || Has domain(s) with predicted RNA binding, pseudouridine synthase activity and role in pseudouridine synthesis || 1 -0.40 -0.95 -0.84 -0.72 0.25 0.39 0.14 0.16 0.14 0.18 0.33 0.67 -0.48 0.82 0.67 0.98
13586 || orf19.4357 || || || Putative protein similar to S. cerevisiae Mgr3p, a subunit of the i-AAA protease supercomplex that degrades misfolded mitochondrial proteins || 1 -0.53 -0.62 -0.91 -1.17 0.39 0.45 0.25 0.27 0.45 0.19 0.79 0.40 -0.07 0.58 0.55 0.22
13587 || orf19.2834 || RPD3 || || Histone deacetylase; regulates frequency of white-to-opaque and opaque-to-white switching; greater expression in white cells than opaque cells; has conserved deacetylation motif || 1 -1.11 -0.85 -0.83 -1.13 0.17 0.41 0.25 0.66 0.53 0.08 0.67 0.57 0.03 0.41 0.45 0.28
13588 || orf19.684 || || || Putative transcription factor with zinc finger DNA-binding motif; heterozygous null mutant exhibits hypersensitivity to parnafungin and cordycepin in the C. albicans fitness test || 1 -0.66 -0.75 -0.64 -0.60 0.14 0.27 0.10 0.19 0.17 -0.13 0.65 0.54 -0.04 0.46 0.26 0.28
13589 || orf19.7112 || FRP2 || || Putative ferric reductase; alkaline induced by Rim101; fluconazole-downregulated; upregulated in the presence of human neutrophils; possibly adherence-induced; regulated by Sef1, Sfu1, and Hap43 || 1 -1.32 -1.02 -1.37 -1.20 0.07 0.16 0.56 0.62 0.26 -0.03 0.82 0.53 -0.79 0.24 0.73 1.05
13590 || orf19.4232 || PTH1 || || Putative gluconate transport protein; antigenic during human oral infection; possibly an essential gene, disruptants not obtained by UAU1 method || 1 -0.52 -0.52 -0.73 -0.96 -0.17 0.00 0.23 0.08 0.22 0.03 0.58 0.20 -0.05 0.29 0.46 0.55
13591 || orf19.1201 || || || Ortholog(s) have serine-tRNA ligase activity, role in invasive growth in response to glucose limitation, mitochondrial seryl-tRNA aminoacylation, pseudohyphal growth, spore germination and mitochondrion localization || 1 -0.88 -0.85 -0.64 -1.18 -0.09 -0.04 0.33 0.21 0.40 0.02 0.45 0.49 -0.11 -0.26 0.63 1.16
13592 || orf19.2129 || || || Ortholog of S. cerevisiae Spo71; a meiosis-specific protein required for spore wall formation during sporulation in S. cerevisiae; possibly an essential gene, disruptants not obtained by UAU1 method || 1 -0.45 -0.37 -0.46 -0.66 0.11 0.21 0.19 0.00 0.53 0.15 0.29 0.40 -0.01 -0.05 0.29 0.52
13593 || orf19.1907 || EMC9 || || Ortholog of S. cerevisiae Nnf2; possible role in chromosome segregation; mutants are viable, induced during the mating process || 1 -1.24 -1.22 -0.38 -0.94 0.41 0.54 -0.00 -0.39 0.09 0.01 0.41 0.61 -0.09 0.56 0.76 1.12
13594 || orf19.6624 || || || Ortholog(s) have GTPase activator activity and clathrin-coated vesicle, endosome localization || 1 -1.44 -1.34 -0.78 -1.06 0.42 0.47 0.09 -0.16 0.03 -0.08 0.58 0.52 -0.26 0.10 0.61 0.81
13595 || orf19.1907 || EMC9 || || Ortholog of S. cerevisiae Nnf2; possible role in chromosome segregation; mutants are viable, induced during the mating process || 1 -1.03 -1.04 -0.99 -1.02 0.51 0.55 0.03 -0.32 -0.10 -0.15 0.55 0.28 0.17 0.28 0.87 1.12
13596 || orf19.5607 || || || Ortholog of C. dubliniensis CD36 : Cd36_63860, C. parapsilosis CDC317 : CPAR2_601140, Candida tenuis NRRL Y-1498 : CANTEDRAFT_92714 and Debaryomyces hansenii CBS767 : DEHA2A06072g || 1 -1.34 -1.20 -1.38 -1.35 0.65 0.49 0.17 -0.44 -0.57 0.19 0.42 0.32 0.06 0.34 0.94 0.87
13597 || orf19.5459 || || || mRNA polyadenylation regulating protein; Hap43-repressed; transcript is upregulated in RHE model of oral candidiasis and in clinical isolates from HIV+ patients with oral candidiasis; Spider biofilm repressed || 1 -0.30 -0.39 -0.38 -0.47 0.20 0.05 0.03 0.09 -0.03 0.06 0.24 0.29 -0.10 0.02 0.40 0.30
13598 || orf19.7497 || || || Ortholog(s) have ubiquitin-protein ligase activity, role in protein ubiquitination involved in ubiquitin-dependent protein catabolic process and Cul3-RING ubiquitin ligase complex, cytoplasm, nucleus localization || 1 -0.42 -0.49 -1.01 -1.06 0.44 0.12 0.00 -0.15 -0.15 -0.08 0.31 0.58 -0.12 0.20 0.61 0.50
13599 || orf19.1555 || SAC3 || || Putative nuclear pore-associated protein, required for small ribosomal subunit biogenesis; possibly an essential gene, disruptants not obtained by UAU1 method || 1 -0.37 -0.42 -0.99 -0.90 0.13 0.27 -0.15 -0.18 -0.12 -0.08 0.34 0.48 -0.00 0.35 0.34 0.41
13600 || orf19.4446 || || || Protein similar to ammomium permeases that is probably inactive, as a mep2 mep3 double homozygous null mutation abolishes cellular ammomium permease activity; fungal-specific (no human or murine homolog) || 1 -0.68 -0.81 -0.99 -1.08 -0.06 0.31 -0.12 -0.19 0.03 0.15 0.27 0.58 -0.40 0.43 0.66 0.55
13601 || orf19.7369 || TRM12 || || Ortholog(s) have S-adenosylmethionine-dependent methyltransferase activity, transferase activity, transferring alkyl or aryl (other than methyl) groups activity and role in tRNA methylation, wybutosine biosynthetic process || 1 -0.92 -0.76 -1.33 -1.84 0.65 0.48 -0.36 -0.65 -0.40 0.11 1.14 0.70 -0.91 0.07 0.86 1.04
13602 || orf19.4357 || || || Putative protein similar to S. cerevisiae Mgr3p, a subunit of the i-AAA protease supercomplex that degrades misfolded mitochondrial proteins || 1 -0.74 -0.90 -0.79 -1.11 0.11 0.41 -0.08 -0.18 0.02 0.11 0.29 0.12 -0.19 0.17 0.51 0.11
13603 || orf19.3402 || FPG1 || || Formamidopyrimidine DNA glycosylase, involved in repair of gamma-irradiated DNA; Hap43p-repressed gene || 1 -0.83 -0.79 -0.62 -0.88 0.39 0.66 0.01 -0.14 0.17 -0.26 0.35 0.45 -0.50 0.33 0.82 0.38
13604 || orf19.3743 || || || Ortholog of C. dubliniensis CD36 : Cd36_27230, C. parapsilosis CDC317 : CPAR2_801320, Candida tenuis NRRL Y-1498 : CANTEDRAFT_113198 and Debaryomyces hansenii CBS767 : DEHA2E23782g || 1 -0.78 -0.75 -0.68 -0.89 0.18 0.43 -0.13 -0.23 0.23 -0.67 0.59 0.54 -0.67 0.01 0.52 0.62
13605 || orf19.6182 || ZCF34 || || Zn(II)2Cys6 transcription factor involved in regulation of multidrug resistance via control of CDR1 expression; mutants display decreased colonization of mouse kidneys; required for yeast cell adherence to silicone substrate || 1 -0.53 -0.46 -0.61 -0.66 0.69 0.29 -0.03 0.03 0.19 -0.27 0.23 0.44 -0.43 0.43 0.48 0.55
13606 || orf19.4295 || || || Ortholog(s) have DNA binding, nucleosome binding, transcription corepressor activity || 1 -0.34 -0.22 -0.55 -0.61 0.00 -0.06 0.05 -0.03 0.11 -0.07 0.38 0.45 -0.12 0.14 -0.07 0.43
13607 || orf19.6238 || || || Ortholog(s) have mitochondrion localization || 1 -0.47 -0.42 -0.57 -0.89 -0.16 0.08 -0.12 0.17 0.43 0.03 0.47 0.74 -0.55 0.09 0.16 0.49
13608 || orf19.3285 || || || Ortholog of C. dubliniensis CD36 : Cd36_25800, Candida tenuis NRRL Y-1498 : CANTEDRAFT_116265, Debaryomyces hansenii CBS767 : DEHA2E17380g and Pichia stipitis Pignal : PICST_62836 || 1 -0.87 -1.17 -0.88 -1.34 -0.48 -0.04 -0.10 0.03 0.36 -0.16 0.14 0.94 -0.49 0.39 0.17 0.70
13609 || orf19.4580 || || || Protein of unknown function; Hap43-repressed gene || 1 -1.71 -1.85 -2.69 -2.34 0.64 0.22 0.64 0.27 -0.10 -1.47 1.63 1.08 -0.05 -0.37 0.48 1.65
13610 || orf19.388 || CAF16 || || ABC family protein, predicted not to be a transporter; Hap43, caspofungin repressed; rat catheter and Spider biofilm repressed || 1 -1.13 -1.17 -1.67 -2.17 0.63 0.34 0.32 0.05 -0.17 -1.11 1.36 0.39 -0.68 -0.12 0.22 1.50
13611 || orf19.388 || CAF16 || || ABC family protein, predicted not to be a transporter; Hap43, caspofungin repressed; rat catheter and Spider biofilm repressed || 1 -0.79 -0.80 -1.07 -1.60 0.49 0.18 0.44 0.21 -0.10 -0.76 1.10 0.17 -0.48 -0.05 -0.05 1.43
13612 || orf19.3447 || || || Ortholog(s) have mannosyltransferase activity, role in ER-associated ubiquitin-dependent protein catabolic process, GPI anchor biosynthetic process, protein processing and endoplasmic reticulum localization || 1 -0.32 -0.47 -1.04 -0.84 -0.19 -0.07 -0.08 0.07 -0.19 -0.50 0.45 0.85 -0.43 0.01 0.48 0.61
13613 || orf19.6296 || VPS22 || || ESCRT-II complex protein with a role in multivesicular body (MVB) trafficking; required for processing of Rim8p; Hap43p-repressed gene || 1 -0.26 -0.11 -0.71 -0.90 -0.09 0.18 0.06 -0.03 0.14 -0.49 0.36 1.00 -0.19 0.48 0.58 0.64
13614 || orf19.7612 || CTM1 || || Putative cytochrome c lysine methyltransferase; regulated by Gcn2 and Gcn4; transcript induced by Mnl1 under weak acid stress; early-stage flow model biofilm induced || 1 -0.53 -0.51 -0.72 -1.09 -0.17 -0.04 0.24 0.10 0.44 -0.48 0.21 0.22 0.38 0.62 0.30 0.47
13615 || orf19.7212 || || || Phosphorylated protein; homozygous transposon insertion causes decreased colony wrinkling in filamentous growth-inducing conditions, but does not block hyphal formation in liquid media; Hap43-repressed || 1 -0.41 -0.41 -0.74 -0.84 0.25 0.12 0.19 0.28 0.61 -0.18 0.19 -0.02 0.07 0.54 0.10 0.35
13616 || orf19.4812 || || || Phosphopantetheine:protein transferase (PPTase); Spider biofilm induced || 1 -0.60 -0.33 -0.78 -0.92 0.13 0.17 0.81 0.30 0.59 -0.29 0.25 0.36 0.05 0.33 -0.00 0.30
13617 || orf19.2137 || || || Ortholog(s) have mitochondrion localization || 1 -0.74 -0.78 -0.75 -1.00 -0.03 0.17 0.70 0.29 0.88 -0.16 0.23 0.28 0.11 -0.21 0.42 0.33
13618 || orf19.6539 || || || Putative trancription modulator; RuvB-like protein family member; heterozygous null mutant displays sensitivity to virgineone || 1 -0.38 -0.45 -1.29 -1.14 -0.02 0.05 0.23 0.34 -0.18 0.20 0.36 0.12 0.09 0.35 -0.01 0.94
13619 || orf19.210 || || || Ortholog(s) have role in protein localization to bud neck and cellular bud neck, cytosol localization || 1 -0.44 -0.38 -0.35 -0.65 0.02 0.04 -0.31 0.09 -0.18 -0.12 0.09 0.17 -0.25 0.55 -0.27 0.43
13620 || orf19.7369 || TRM12 || || Ortholog(s) have S-adenosylmethionine-dependent methyltransferase activity, transferase activity, transferring alkyl or aryl (other than methyl) groups activity and role in tRNA methylation, wybutosine biosynthetic process || 1 -0.61 -0.43 -0.45 -0.72 0.08 0.34 -0.31 -0.01 -0.08 0.10 0.14 0.22 -0.72 0.34 0.20 0.47
13621 || orf19.578 || || || Ortholog(s) have Rab GTPase activator activity and role in actin filament organization, endocytosis, exocytosis, regulation of GTPase activity, regulation of protein localization || 1 -0.59 -0.82 -0.24 -0.62 -0.01 0.23 -0.33 -0.40 0.04 0.00 -0.03 0.67 -0.26 0.40 0.37 0.24
13622 || orf19.4848 || SKI3 || || Ortholog(s) have role in negative regulation of G2/M transition of mitotic cell cycle, nuclear-transcribed mRNA catabolic process, 3'-5' exonucleolytic nonsense-mediated decay, nuclear-transcribed mRNA catabolic process, non-stop decay || 1 -0.53 -0.70 -0.47 -0.32 -0.06 0.01 -0.07 -0.11 0.08 -0.01 0.22 0.71 -0.29 0.24 0.22 0.46
13623 || orf19.3111 || PRA1 || || Cell surface protein that sequesters zinc from host tissue; enriched at hyphal tips; released extracellularly; binds to host complement regulators; mediates leukocyte adhesion and migration; immunogenic in mouse; produced at ambient pH || 1 -1.31 -1.14 -0.32 -0.69 -0.26 0.14 -0.45 -0.56 0.03 -0.26 0.21 1.06 -0.47 0.11 0.12 1.16
13624 || orf19.7185 || || || Ortholog of C. dubliniensis CD36 : Cd36_73630, C. parapsilosis CDC317 : CPAR2_805330, Candida tenuis NRRL Y-1498 : CANTEDRAFT_119330 and Debaryomyces hansenii CBS767 : DEHA2G16544g || 1 -0.57 -0.79 -0.17 -0.47 -0.07 0.28 -0.22 0.05 0.19 -0.05 0.62 0.57 -0.17 0.12 -0.12 0.53
13625 || orf19.2325 || || || Ortholog(s) have RNA polymerase III type 1 promoter sequence-specific DNA binding and RNA polymerase III type 1 promoter sequence-specific DNA binding TFIIIB recruiting transcription factor activity, more || 1 -0.63 -0.48 -0.14 -0.41 -0.51 -0.46 -0.09 0.00 -0.03 -0.24 0.35 0.44 0.08 0.42 -0.23 1.02
13626 || orf19.4734 || || || Protein of unknown function; Hap43-repressed || 1 -0.34 -0.53 -0.30 -0.58 -0.23 -0.18 -0.11 -0.03 0.05 -0.55 0.25 0.36 -0.16 0.44 -0.29 0.86
13627 || orf19.2665 || MSN5 || || Predicted karyopherin involved in nuclear import and export of proteins; flow model biofilm induced; Spider biofilm induced || 1 -0.47 -0.49 -0.02 -0.51 -0.16 -0.21 -0.14 -0.09 -0.01 -0.47 0.23 0.32 -0.20 0.49 0.22 0.63
13628 || orf19.5849 || CWT1 || || Zn2Cys6 transcription factor involved in negative regulation of nitrosative stress response; mutant has cell wall defects; transcription increased at stationary phase; has predicted PAS domain; similar to S. cerevisiae Rds2p || 1 -0.50 -0.77 -0.20 -0.64 -0.37 0.04 -0.23 -0.13 -0.25 -0.52 0.41 0.33 -0.06 0.54 0.22 0.66
13629 || orf19.3699 || TEP1 || || Putative protein phosphatase of the PTP family (tyrosine-specific), similar to S. cerevisiae Tep1p || 1 -0.64 -0.68 -0.97 -0.54 -0.50 -0.14 0.11 0.10 0.02 -0.36 0.33 0.88 -0.51 0.78 -0.11 0.69
13630 || orf19.5880 || || || Putative voltage-gated chloride channel; predicted role in copper ion and iron ion homeostasis; flow model biofilm induced || 1 -0.40 -0.35 -0.57 -0.43 -0.31 -0.35 -0.09 -0.02 -0.08 -0.29 0.34 0.16 -0.34 0.30 -0.04 0.28
13631 || orf19.5357 || AKL1 || || Putative serine/threonine protein kinase; induced during the mating process || 1 -0.47 -0.41 -0.42 -0.56 0.02 -0.29 -0.03 0.01 -0.06 -0.33 0.26 0.02 -0.13 0.02 0.51 0.18
13632 || orf19.1275 || GAT1 || || GATA-type transcription factor; regulator of nitrogen utilization; required for nitrogen catabolite repression and utilization of isoleucine, tyrosine and tryptophan N sources; required for virulence in a mouse systemic infection model || 1 -1.23 -1.60 -1.59 -1.46 -0.63 -0.95 0.14 0.06 -0.85 -1.63 0.54 0.34 -0.12 -0.77 0.98 1.29
13633 || orf19.6232 || NPR1 || || Predicted serine/threonine protein kinase, involved in regulation of ammonium transport; induced in core stress response; Hap43p-repressed gene || 1 -0.80 -0.96 -1.14 -1.15 -0.61 -0.40 0.07 -0.09 0.02 -0.95 0.63 0.47 0.19 0.27 0.58 0.95
13634 || orf19.894 || || || Ortholog(s) have guanyl-nucleotide exchange factor activity, role in retrograde transport, endosome to Golgi and Golgi membrane, Ric1p-Rgp1p complex, guanyl-nucleotide exchange factor complex localization || 1 -0.29 -0.37 -0.43 -0.56 0.01 -0.23 0.08 0.20 -0.28 -0.42 0.34 0.22 0.03 0.14 0.20 0.17
13635 || orf19.7052 || || || Putative polyphosphatidylinositol phosphatase; possibly an essential gene, disruptants not obtained by UAU1 method || 1 -0.12 -0.44 -0.53 -0.54 -0.02 -0.33 0.09 -0.07 -0.20 -0.34 0.38 0.00 0.10 -0.27 0.25 0.15
13636 || orf19.5814 || || || Protein of unknown function; Spider biofilm induced || 1 0.05 -0.19 -0.59 -0.33 -0.30 -0.71 0.36 0.55 0.19 0.27 0.48 0.43 -0.03 -0.34 0.67 0.12
13637 || orf19.1473 || || || 2-hydroxyacid dehydrogenase domain-containing protein; Hap43-repressed gene; induced by alpha pheromone in SpiderM medium || 1 0.13 -0.18 -1.73 -2.17 -0.17 -2.40 0.25 -0.40 0.46 -0.08 0.44 1.43 -0.00 -0.24 0.75 0.26
13638 || orf19.1473 || || || 2-hydroxyacid dehydrogenase domain-containing protein; Hap43-repressed gene; induced by alpha pheromone in SpiderM medium || 1 -0.12 -0.44 -3.52 -4.01 -1.01 -4.24 -0.55 -0.41 0.24 0.02 0.39 1.42 0.12 -0.22 0.15 -0.29
13639 || orf19.7610 || PTP3 || || Putative protein tyrosine phosphatase; hypha induced; alkaline induced; regulated by Efg1, Ras1, cAMP pathways; mutants are viable; Spider biofilm induced; rat catheter biofilm repressed; flow model biofilm repressed || 1 0.19 0.02 -1.11 -1.19 -0.60 -0.88 0.50 0.26 -0.04 -0.19 0.58 0.40 0.53 -0.53 0.13 -0.35
13640 || orf19.7610 || PTP3 || || Putative protein tyrosine phosphatase; hypha induced; alkaline induced; regulated by Efg1, Ras1, cAMP pathways; mutants are viable; Spider biofilm induced; rat catheter biofilm repressed; flow model biofilm repressed || 1 -0.07 -0.19 -1.43 -1.25 -0.82 -1.01 0.30 -0.04 0.05 -0.38 0.47 0.44 0.24 -0.29 -0.02 -0.57
13641 || orf19.7610 || PTP3 || || Putative protein tyrosine phosphatase; hypha induced; alkaline induced; regulated by Efg1, Ras1, cAMP pathways; mutants are viable; Spider biofilm induced; rat catheter biofilm repressed; flow model biofilm repressed || 1 -0.00 -0.17 -0.91 -0.71 -0.80 -0.67 0.12 -0.02 0.24 -0.19 0.47 0.61 0.35 -0.54 -0.04 -0.17
13642 || orf19.477 || || || Ortholog(s) have role in mitochondrial translation and mitochondrion localization || 1 0.57 0.13 -1.65 -1.27 -0.49 -0.77 0.47 0.49 0.16 0.59 0.24 0.37 0.21 -0.46 0.33 -0.77
13643 || orf19.4537 || || || Ortholog(s) have RNA polymerase II core binding, RNA polymerase II regulatory region DNA binding, core RNA polymerase II recruiting transcription factor activity || 1 0.01 -0.03 -0.56 -0.45 -0.53 -0.74 -0.01 0.30 -0.24 0.49 0.47 0.44 0.42 0.24 0.48 -0.00
13644 || orf19.4086 || || || Ortholog(s) have cytoplasm localization || 1 -0.03 -0.26 -0.60 -0.43 -0.07 -0.76 0.56 0.22 0.11 0.39 0.30 -0.25 0.45 0.55 0.55 -0.31
13645 || orf19.3755 || || || Ortholog(s) have structural constituent of ribosome activity and mitochondrial large ribosomal subunit localization || 1 -0.25 -0.39 -0.89 -1.17 -0.40 -1.53 0.44 0.73 -0.18 0.39 0.65 -0.29 0.88 0.45 0.37 -0.94
13646 || orf19.4028 || || || Putative cis-prenyltransferase involved in dolichol synthesis; participates in endoplasmic reticulum (ER) protein sorting; flow model biofilm induced || 1 -0.10 -0.07 -0.72 -0.40 -0.73 -1.01 0.08 0.23 -0.04 0.29 0.49 -0.13 0.16 0.16 0.61 -0.53
13647 || orf19.6780 || MET8 || || Putative bifunctional dehydrogenase and ferrochelatase with a predicted role in siroheme biosynthesis; regulated by Gcn2p and Gcn4p || 1 0.05 0.33 -0.96 -0.64 -0.23 -0.96 -0.04 0.34 -0.34 0.22 0.23 -0.05 0.35 0.31 0.03 -0.83
13648 || orf19.6080 || || || Ortholog(s) have role in mitotic spindle orientation checkpoint and spindle pole body localization || 1 0.03 -0.05 -0.92 -0.54 -0.76 -1.53 0.43 0.18 -0.29 -0.30 0.58 -0.31 0.32 -0.45 -0.02 -0.17
13649 || orf19.3173 || || || Ortholog(s) have Golgi apparatus, endoplasmic reticulum localization || 1 0.08 0.14 -0.78 -0.94 -0.63 -0.92 0.47 0.61 -0.03 0.32 0.54 -0.18 0.11 -0.34 -0.05 0.11
13650 || orf19.588 || || || Ortholog(s) have role in aerobic respiration and mitochondrial intermembrane space, nucleus localization || 1 -0.05 -0.25 -1.45 -0.87 -0.62 -1.28 0.44 0.29 -0.61 0.35 0.97 -0.11 -0.10 -0.73 -0.39 -0.41
13651 || orf19.5493 || GSP1 || || Small RAN G-protein; essential; no prenylation predicted; can rescue S. cerevisiae gsp1 viability; macrophage/pseudohyphal-induced; transcript not regulated by white-opaque, yeast-hypha switching; GlcNAc-induced; Spider biofilm repressed || 1 -0.26 -0.39 -1.28 -0.96 -0.66 -0.96 0.60 0.47 -0.53 -0.25 0.89 -0.20 -0.08 -0.86 -0.46 -0.22
13652 || orf19.5493 || GSP1 || || Small RAN G-protein; essential; no prenylation predicted; can rescue S. cerevisiae gsp1 viability; macrophage/pseudohyphal-induced; transcript not regulated by white-opaque, yeast-hypha switching; GlcNAc-induced; Spider biofilm repressed || 1 -0.25 -0.30 -1.26 -1.03 -0.57 -1.38 0.76 0.87 -0.81 -0.12 1.03 -0.32 0.12 -0.76 -0.43 -0.46
13653 || orf19.4312 || || || Ortholog(s) have TBP-class protein binding, transcription cofactor activity || 1 0.04 -0.07 -0.26 -0.35 -0.10 -0.25 0.17 0.09 -0.28 0.04 0.36 -0.10 0.02 -0.00 0.07 -0.17
13654 || orf19.1468 || CDC55 || || Ortholog(s) have protein phosphatase type 2A regulator activity, protein serine/threonine phosphatase activity || 1 -0.26 -0.27 -1.06 -1.24 -0.18 -0.88 0.42 0.53 -0.21 -0.18 0.89 -0.18 -0.05 -0.20 0.53 -0.03
13655 || orf19.6531.1 || TOM7 || || Predicted component of the TOM (translocase of outer membrane) complex involved in protein translocation into mitochondria; flucytosine induced || 1 -0.30 -0.49 -2.02 -2.02 -0.04 -1.46 0.84 1.13 -0.55 0.24 1.34 -0.12 0.10 -0.30 0.08 -0.79
13656 || orf19.3599 || TIF4631 || || Putative translation initiation factor eIF4G; overexpression causes hyperfilamentation; hyphal- and macrophage-induced; genes encoding some translation factors are downregulated upon phagocytosis by murine macrophage || 1 0.26 -0.10 -1.55 -0.93 0.13 -0.97 0.48 0.85 -0.39 0.24 0.78 -0.46 0.03 -0.28 0.24 -0.31
13657 || orf19.6424 || || || Ortholog(s) have SUMO ligase activity and role in cellular response to DNA damage stimulus, hyphal growth, mitotic spindle elongation, protein sumoylation, regulation of mitotic cell cycle || 1 0.23 0.36 -0.79 -0.62 -0.13 -0.68 0.65 0.88 -0.08 -0.28 1.19 -0.46 0.36 -0.14 -0.35 -0.50
13658 || orf19.2558 || || || Has domain(s) with predicted zinc ion binding activity and nucleus localization || 1 -0.05 0.15 -0.25 -0.43 -0.19 -0.72 0.39 0.31 -0.08 -0.18 0.71 -0.22 0.22 -0.05 -0.01 -0.08
13659 || orf19.3940 || || || Ortholog of C. dubliniensis CD36 : Cd36_54170, C. parapsilosis CDC317 : CPAR2_100960, Candida tenuis NRRL Y-1498 : CANTEDRAFT_96367 and Debaryomyces hansenii CBS767 : DEHA2G24618g || 1 0.12 0.29 -1.15 -0.50 -0.76 -0.92 0.52 0.43 -0.35 -0.20 1.02 -0.42 0.27 -0.03 0.39 -0.01
13660 || orf19.2964 || || || Ortholog(s) have DNA translocase activity || 1 -0.06 0.06 -0.89 -0.58 -0.41 -0.82 0.52 0.62 -0.57 -0.08 0.69 -0.10 0.41 0.23 0.05 0.04
13661 || orf19.239 || || || Putative ATP-dependent helicase; induced by nitric oxide || 1 0.38 0.51 -0.65 -0.33 -0.44 -1.14 0.56 0.88 -0.81 -0.11 0.85 -0.10 0.56 0.16 -0.15 -0.18
13662 || orf19.6314 || RPB8 || || Putative subunit of RNA polymerases I, II, and III; regulated by Gcn4p; repressed in response to amino acid starvation (3-aminotriazole treatment); heterozygous null mutant exhibits resistance to parnafungin || 1 0.30 -0.03 -1.11 -0.52 -0.36 -0.49 0.29 0.66 -0.82 0.45 0.54 -0.16 0.49 -0.48 0.30 -0.30
13663 || orf19.4622 || || || Ortholog(s) have role in telomere maintenance, transcription-coupled nucleotide-excision repair, ubiquitin-dependent protein catabolic process and nucleus localization || 1 -0.11 -0.20 -0.66 -0.36 -0.14 -0.80 0.25 0.72 -0.66 -0.15 0.95 -0.14 0.18 -0.70 0.66 -0.24
13664 || orf19.709 || PUP2 || || Alpha5 subunit of the 20S proteasome; macrophage/pseudohyphal-repressed; regulated by Gcn2p and Gcn4p; protein present in exponential and stationary growth phase yeast cultures || 1 0.15 0.20 -0.23 -0.16 -0.01 -0.40 0.33 0.39 -0.08 -0.18 0.46 0.01 -0.18 -0.02 0.35 0.36
13665 || orf19.3683 || AGE3 || || Putative ADP-ribosylation factor GTPase activating protein, functional ortholog of S. cerevisiae GCS1; mutation affects endocytosis, hyphal growth, chemical and drug resistance, and sensitivity to cell wall inhibitors || 1 0.06 0.08 -0.79 -1.04 0.25 -1.18 0.50 0.73 -0.19 0.05 1.27 0.26 0.26 0.14 0.34 0.19
13666 || orf19.5397 || || || Putative conserved oligomeric Golgi complex subunit; decreased transcription is observed upon fluphenazine treatment || 1 0.29 0.48 -0.66 -0.88 0.26 -0.55 0.75 0.92 -0.25 -0.16 1.09 0.36 0.03 0.23 0.40 0.36
13667 || orf19.5968 || RDI1 || || Putative rho GDP dissociation inhibitor; transposon mutation affects filamentous growth; farnesol, filament-induced; regulated by Nrg1, Tup1; protein levels low in stationary phase yeast || 1 0.14 0.12 -0.26 -0.46 -0.05 -0.30 0.30 0.36 -0.07 -0.06 0.56 0.30 0.05 0.10 0.41 0.02
13668 || orf19.1267.1 || || || Ortholog(s) have enzyme activator activity, role in iron-sulfur cluster assembly and extrinsic to mitochondrial inner membrane, mitochondrial matrix localization || 1 0.46 0.51 -0.57 -0.87 0.34 -0.75 0.92 1.25 -0.01 0.25 1.11 -0.14 0.22 0.17 0.84 0.07
13669 || orf19.709 || PUP2 || || Alpha5 subunit of the 20S proteasome; macrophage/pseudohyphal-repressed; regulated by Gcn2p and Gcn4p; protein present in exponential and stationary growth phase yeast cultures || 1 0.35 0.40 -0.49 -0.53 0.02 -0.72 0.81 0.61 -0.28 -0.24 0.60 -0.03 0.28 0.13 0.22 0.30
13670 || orf19.4084 || KIS1 || || Snf1p complex scaffold protein; similar to S. cerevisiae Gal83p and Sip2p with regions of similarity to Sip1p (ASC and KIS domain); interacts with Snf4p; mutants are hypersensitive to caspofungin and hydrogen peroxide; Hap43p-repressed gene || 1 0.31 0.10 -0.36 -0.37 -0.28 -0.55 0.62 0.63 -0.17 -0.09 0.66 -0.01 0.35 0.34 0.45 0.43
13671 || orf19.4430 || || || Ortholog(s) have ubiquitin binding activity, role in proteasome-mediated ubiquitin-dependent protein catabolic process and cytoplasm, nucleus localization || 1 0.54 0.14 -1.03 -0.99 -0.10 -0.92 0.68 0.84 -0.14 -0.25 0.53 -0.01 0.11 -0.06 0.81 0.47
13672 || orf19.5968 || RDI1 || || Putative rho GDP dissociation inhibitor; transposon mutation affects filamentous growth; farnesol, filament-induced; regulated by Nrg1, Tup1; protein levels low in stationary phase yeast || 1 0.23 0.18 -0.72 -0.77 0.14 -0.28 0.46 0.53 -0.23 -0.14 0.68 0.16 -0.05 -0.26 0.69 0.32
13673 || orf19.6796 || YSA1 || || Predicted Nudix hydrolase family member with ADP-ribose pyrophosphatase activity; role in metabolism of O-acetyl-ADP-ribose to AMP and acetylated ribose 5'-phosphate; rat catheter biofilm repressed || 1 -0.14 0.07 -1.14 -0.95 -0.04 -0.30 0.69 0.69 -0.58 -0.54 1.24 0.26 -0.00 -0.19 0.47 0.27
13674 || orf19.3561 || CDC7 || || Putative kinase; cell-cycle regulated periodic mRNA expression; S. cerevisiae ortholog is not cell-cycle regulated; possibly an essential gene, disruptants not obtained by UAU1 method || 1 -0.15 0.01 -0.87 -1.00 0.32 -0.48 0.41 0.66 -0.73 -0.04 1.12 0.14 0.23 0.19 0.30 0.54
13675 || orf19.2510 || || || Ortholog(s) have role in protein folding, tubulin complex assembly || 1 -0.03 0.19 -0.97 -1.30 0.17 -0.78 0.27 0.56 -0.05 -0.26 0.81 0.46 -0.02 -0.07 0.43 0.52
13676 || orf19.5201 || || || Ortholog(s) have structural constituent of ribosome activity and mitochondrial small ribosomal subunit localization || 1 0.18 0.13 -0.95 -1.18 0.27 -0.65 0.52 0.95 -0.06 0.54 0.80 -0.17 0.50 -0.31 0.55 -0.35
13677 || orf19.7492 || SWC4 || || Subunit of the NuA4 histone acetyltransferase complex || 1 0.04 0.08 -0.47 -0.54 -0.08 -0.47 0.60 0.63 -0.31 0.06 0.55 -0.24 0.59 -0.08 0.37 -0.12
13678 || orf19.6406 || || || Ortholog(s) have role in regulation of sporulation resulting in formation of a cellular spore and cytosol, mitochondrial ribosome, nucleus localization || 1 -0.35 0.87 -0.76 -1.09 0.55 -0.38 0.65 0.87 0.17 0.21 1.29 0.36 0.56 0.09 0.59 -0.09
13679 || orf19.5854.1 || || || Has domain(s) with predicted ATP binding, ATPase activity || 1 -0.11 -0.01 -0.94 -0.79 -0.03 -0.29 0.61 0.97 -0.35 -0.12 0.18 -0.09 0.44 0.40 0.54 0.08
13680 || orf19.6718 || || || Has domain(s) with predicted sequence-specific DNA binding activity || 1 0.08 0.19 -0.47 -0.53 -0.14 -0.31 0.19 0.12 -0.25 0.14 0.72 -0.28 0.26 0.35 0.17 0.12
13681 || orf19.121 || ARC18 || || Putative ARP2/3 complex subunit; mutation confers hypersensitivity to cytochalasin D || 1 0.37 0.16 -0.55 -0.55 0.45 -0.35 0.15 0.28 -0.28 -0.06 0.77 0.03 -0.08 0.44 0.17
13682 || orf19.121 || ARC18 || || Putative ARP2/3 complex subunit; mutation confers hypersensitivity to cytochalasin D || 1 0.68 0.50 -0.98 -0.87 0.47 -0.55 -0.04 0.26 -0.66 -0.43 0.87 -0.18 -0.20 -0.01 0.43 -0.01
13683 || orf19.193 || || || Ortholog of C. dubliniensis CD36 : Cd36_19310, C. parapsilosis CDC317 : CPAR2_209710, Candida tenuis NRRL Y-1498 : CANTEDRAFT_113479 and Debaryomyces hansenii CBS767 : DEHA2C15114g || 1 0.78 0.26 -0.78 -0.64 0.47 -0.74 0.39 0.37 -0.83 -0.12 0.47 -0.26 0.06 0.35 0.58 0.12
13684 || orf19.7216 || YPT52 || || Rab-family GTPase involved in vacuolar trafficking, colocolizes with Vps1p and Ypt53p in late endosome || 1 0.28 0.21 -0.42 -0.38 0.03 -0.32 -0.07 0.27 -0.40 0.17 0.28 0.01 -0.25 0.25 0.43 -0.16
13685 || orf19.2733 || || || Putative subunit of phosphatidylinositol 3-kinase complexes I and II; transcription is activated in the presence of elevated CO2 || 1 -0.06 0.01 -0.69 -0.55 0.33 -0.72 -0.11 0.01 -0.52 -0.08 0.00 0.02 -0.05 -0.02 0.74 0.06
13686 || orf19.6269 || || || Ortholog of C. dubliniensis CD36 : Cd36_05990, Candida tenuis NRRL Y-1498 : CANTEDRAFT_91852, Debaryomyces hansenii CBS767 : DEHA2G15356g and Pichia stipitis Pignal : PICST_87044 || 1 0.18 0.39 -1.07 -1.41 0.39 -1.33 0.15 0.31 -0.65 -0.31 0.13 -0.23 0.32 -0.05 0.63 0.01
13687 || orf19.7014 || || || Putative protein of unknown function; transcription is positively regulated by Tbf1p; overlaps orf19.7015 || 1 0.45 -0.32 -1.38 -1.17 0.15 -1.44 0.63 0.49 -0.89 -0.14 0.02 0.95 -0.35
13688 || orf19.6269 || || || Ortholog of C. dubliniensis CD36 : Cd36_05990, Candida tenuis NRRL Y-1498 : CANTEDRAFT_91852, Debaryomyces hansenii CBS767 : DEHA2G15356g and Pichia stipitis Pignal : PICST_87044 || 1 0.33 0.55 -1.49 -1.39 0.61 -0.52 0.22 0.14 -0.27 -0.65 0.02 -0.23 0.40 -0.09 1.16 -0.72
13689 || orf19.5748 || || || Ortholog of C. dubliniensis CD36 : Cd36_64250, Candida tenuis NRRL Y-1498 : cten_CGOB_00218, Debaryomyces hansenii CBS767 : DEHA2E19888g and Spathaspora passalidarum NRRL Y-27907 : spas_CGOB_00025 || 1 -0.03 -0.20 -1.15 -1.68 -0.06 0.39 0.38 -0.36 0.32 -0.07 0.07 -0.04 0.36 -0.06 0.83 0.10
13690 || orf19.2921 || || || Ortholog(s) have alpha-tubulin binding activity, role in protein folding, tubulin complex assembly and cytosol, nucleus localization || 1 0.05 -0.19 -0.81 -0.94 -0.17 -0.23 0.31 -0.12 0.22 0.01 0.22 0.22 -0.08 -0.29 0.87 0.48
13691 || orf19.3969 || SFL2 || || Transcription factor involved in regulation of morphogenesis; required for filamentous growth, for virulence in RHE model but not in mice; induced upon RHE infection but C. dubliniensis ortholog is not; Spider biofilm induced || 1 -0.20 -0.79 -2.08 -1.30 -0.19 0.11 0.34 -0.37 0.16 -0.65 0.91 0.35 0.23 -0.59 1.06 1.01
13692 || orf19.6193 || TAF145 || || Protein similar to S. cerevisiae Taf145p, a component of RNA polymerase II transcription factor TFIID; flucytosine repressed; likely to be essential for growth, based on an insertional mutagenesis strategy || 1 -0.15 -0.12 -0.76 -0.63 0.33 0.01 -0.14 -0.08 -0.43 -0.29 0.20 0.09 0.52 -0.18 0.48 0.07
13693 || orf19.1383 || || || Protein of unknown function; induced by alpha pheromone in SpiderM medium || 1 -0.15 -0.99 -1.22 -0.61 0.41 -0.05 0.04 -0.04 -0.52 -0.07 0.41 0.23 0.44 -0.27 0.62 -0.14
13694 || orf19.3735 || || || Protein of unknown function; induced by alpha pheromone in SpiderM medium || 1 0.05 -0.42 -0.87 0.43 -0.03 0.28 -0.05 0.15 -0.26 0.18 0.50 0.61 -0.29
13695 || orf19.6266 || || || Protein of unknown function; Spider biofilm induced || 1 -0.11 -0.25 -0.81 -1.07 0.17 0.14 0.16 -0.26 -0.08 0.24 0.31 0.78 0.53 -0.19 0.74 -0.25
13696 || orf19.230 || || || Ortholog of S. cerevisiae Pet111; a mitochondrial translational activator specific for the COX2 mRNA; Hap43-induced gene || 1 0.21 0.16 -0.66 -0.81 0.49 0.12 0.02 0.09 -0.43 -0.40 0.17 0.78 0.28 -0.29 0.64 -0.11
13697 || orf19.3252 || DAL81 || || Zn(II)2Cys6 transcription factor; ortholog of S. cerevisiae Dal81, involved in the regulation of nitrogen-degradation genes; required for yeast cell adherence to silicone substrate; Spider biofilm induced || 1 -0.03 -0.35 -0.57 -0.47 0.57 0.30 0.04 -0.32 -0.55 -0.21 0.12 0.96 0.22 -0.58 0.76 0.19
13698 || orf19.3912 || GLN3 || || GATA transcription factor, involved in regulation of nitrogen starvation-induced filamentous growth; regulates transcription of Mep2 ammonium permease; regulated by Gcn2 and Gcn4; mRNA binds She3; Spider biofilm induced || 1 -0.69 -0.63 -0.49 -0.71 0.17 0.08 0.20 -0.43 0.02 -0.07 -0.16 0.39 0.40 -0.30 1.15 -0.15
13699 || orf19.7376 || || || Ortholog of C. dubliniensis CD36 : Cd36_85880, C. parapsilosis CDC317 : CPAR2_806870, Candida tenuis NRRL Y-1498 : CANTEDRAFT_96983 and Debaryomyces hansenii CBS767 : DEHA2D16148g || 1 -0.72 -0.49 -0.88 -0.88 -0.02 -0.14 0.08 -0.50 0.13 0.19 -0.14 0.24 0.57 -0.39 0.34 0.11
13700 || orf19.5586 || || || Ortholog(s) have phosphatidylinositol-3,5-bisphosphate 5-phosphatase activity, role in phosphatidylinositol dephosphorylation and PAS complex, cytosol, extrinsic to membrane, fungal-type vacuole membrane localization || 1 -0.40 -0.29 -0.58 -0.63 -0.01 -0.27 0.47 -0.25 -0.08 -0.31 -0.11 0.28 0.26 -0.44 0.18 0.01
13701 || orf19.6469 || || || Predicted ORF in retrotransposon Tca11 with similarity to the Gag-Pol region of retrotransposons, which encodes nucleocapsid-like protein, reverse transcriptase, protease, and integrase || 1 -0.77 -0.68 -0.65 -0.77 0.59 0.19 0.23 -0.19 0.23 -0.44 -0.16 0.07 0.17 -0.41 0.21 0.18
13702 || orf19.6469 || || || Predicted ORF in retrotransposon Tca11 with similarity to the Gag-Pol region of retrotransposons, which encodes nucleocapsid-like protein, reverse transcriptase, protease, and integrase || 1 -0.61 -0.57 -0.57 -0.64 0.58 0.42 0.38 0.16 0.39 -0.27 -0.08 0.06 0.26 -0.51 0.40 -0.07
13703 || orf19.5681 || || || Ortholog of C. dubliniensis CD36 : Cd36_50190, C. parapsilosis CDC317 : CPAR2_302680, Candida tenuis NRRL Y-1498 : CANTEDRAFT_109949 and Debaryomyces hansenii CBS767 : DEHA2G00814g || 1 -0.55 -0.43 -0.81 -0.52 0.70 -0.22 -0.40 -0.29 -0.04 0.15 -0.03 -0.16 -0.27 -0.74 0.10 -0.14
13704 || orf19.7152 || || || Protein similar to Aspergillus CYSK O-acetylserine sulfhydrylase, suggesting that C. albicans uses an O-acetyl-serine (OAS) pathway of sulfur assimilation; upregulated in biofilm; protein level decreases in stationary phase cultures || 1 -0.43 -0.41 -0.68 -0.46 0.30 -0.38 0.05 -0.17 -0.54 -0.16 0.19 -0.00 -0.51 -0.69 0.01 0.20
13705 || orf19.5365 || || || S. cerevisiae ortholog YMR259C interacts with Trm7 for 2'-O-methylation of C32 of substrate tRNAs; downregulated by fluphenazine treatment or in an azole-resistant strain that overexpresses CDR1 and CDR2 || 1 -0.49 -0.66 -1.15 -1.04 0.56 -0.30 0.53 -0.14 -0.41 -0.05 0.02 -0.72 -0.62 -0.47 0.00 -0.33
13706 || orf19.4948 || REX3 || || Ortholog(s) have 3'-5'-exoribonuclease activity and role in U5 snRNA 3'-end processing, exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) || 1 -0.48 -0.54 -1.36 -0.73 0.19 -0.17 0.02 -0.29 0.15 0.39 -0.28 -0.76 -0.34 0.03 0.09 -0.28
13707 || orf19.1648 || RAD50 || || Putative DNA double-strand break repair factor; involved in response to oxidative stress and drug resistance; flow model biofilm repressed || 1 -0.02 -0.53 -0.82 -0.23 0.17 -0.73 -0.01 0.21 0.01 0.26 0.10 -0.29 -0.86 -0.27 -0.02 0.03
13708 || orf19.4711 || || || Ortholog of C. dubliniensis CD36 : Cd36_40890, C. parapsilosis CDC317 : CPAR2_401100, Candida tenuis NRRL Y-1498 : CANTEDRAFT_119698 and Debaryomyces hansenii CBS767 : DEHA2G22154g || 1 -0.19 -0.33 -0.75 -0.51 -0.16 -0.54 -0.22 -0.17 -0.22 0.06 -0.06 -0.15 -0.75 -0.17 0.05 0.34
13709 || orf19.1123 || || || Dubious open reading frame || 1 -0.20 -0.54 -0.54 -0.69 -0.34 -0.92 -0.28 -0.05 -0.35 0.01 0.06 -0.59 -1.30 -0.22
13710 || orf19.3960 || HYS2 || || Putative DNA polymerase III (delta) subunit with a predicted role in DNA replication and DNA repair; cell-cycle regulated periodic mRNA expression || 1 -0.03 -0.14 -0.61 -0.02 -0.20 -0.59 -0.46 0.16 -0.62 0.70 0.26 -0.09 -0.66 -0.00 -0.53 0.09
13711 || orf19.4813 || GUA1 || || Putative GMP synthase, involved in the final step of guanine biosynthesis; soluble protein in hyphae; flucytosine induced; macrophage-downregulated protein abundance; protein level decreases in stationary phase cultures || 1 0.12 -0.03 -0.44 -0.31 -0.61 -0.46 -0.49 0.10 -0.77 0.61 -0.23 -0.54 -0.88 0.14 -1.15 -0.07
13712 || orf19.4813 || GUA1 || || Putative GMP synthase, involved in the final step of guanine biosynthesis; soluble protein in hyphae; flucytosine induced; macrophage-downregulated protein abundance; protein level decreases in stationary phase cultures || 1 -0.21 -0.10 -0.83 -0.25 -0.69 -0.56 -0.68 0.11 -0.75 0.58 -0.28 -0.61 -0.84 -0.09 -1.21 -0.39
13713 || orf19.6568 || SMC6 || || Putative structural maintenance of chromosomes (SMC) protein; Hap43-induced; cell-cycle regulated periodic mRNA expression; S. cerevisiae ortholog not cell-cycle regulated; Spider biofilm induced || 1 -0.32 -0.14 -0.55 -0.08 -0.51 -1.14 -0.56 -0.28 -1.08 0.43 0.07 -0.58 -0.58 0.16 -0.97 -0.35
13714 || orf19.7594 || || || Protein of unknown function; Spider biofilm induced || 1 -0.02 -0.27 -0.69 -0.16 -0.15 -1.12 -0.52 -0.22 -0.85 -0.14 0.01 -0.21 -0.69 -0.28 -0.87 -0.22
13715 || orf19.5851 || STE13 || || Putative pheromone-processing dipeptidyl aminopeptidase; possible Kex2 substrate; transposon mutation affects filamentous growth; induced by low nitrogen, germ tube formation; flow model biofilm repressed || 1 -0.39 -0.50 -1.03 -0.49 -0.05 -1.13 -0.34 -0.09 -0.81 -0.08 0.07 -0.35 -1.12 -0.55 -0.67 -0.11
13716 || orf19.7182 || || || Ortholog(s) have RNA binding activity, role in tRNA modification and cytoplasm, nucleus localization || 1 0.01 0.12 -1.25 -0.85 0.28 0.02 0.26 0.22 -0.39 0.30 0.19 -0.67 -0.56 0.14 -0.85 -0.45
13717 || orf19.5365 || || || S. cerevisiae ortholog YMR259C interacts with Trm7 for 2'-O-methylation of C32 of substrate tRNAs; downregulated by fluphenazine treatment or in an azole-resistant strain that overexpresses CDR1 and CDR2 || 1 -0.34 -0.23 -0.95 -0.81 0.31 -0.13 0.10 0.09 -0.08 0.21 -0.27 -0.82 -0.75 -0.02 -0.42 -0.44
13718 || orf19.4532 || || || Protein of unknown function; present in exponential and stationary growth phase yeast cultures || 1 -0.40 -0.46 -0.60 -0.68 0.30 0.21 -0.30 0.17 -0.55 0.55 0.04 -0.29 -1.48 -0.09 -0.55 -0.37
13719 || orf19.4532 || || || Protein of unknown function; present in exponential and stationary growth phase yeast cultures || 1 -0.63 -0.58 -0.94 -0.57 0.24 0.05 -0.44 0.02 -0.44 0.41 -0.12 -0.31 -0.86 -0.47 -0.54 -0.26
13720 || orf19.6676 || || || Has domain(s) with predicted diphthine synthase activity and role in peptidyl-diphthamide biosynthetic process from peptidyl-histidine || 1 -0.37 -0.47 -0.96 -0.66 0.59 0.31 -0.11 0.11 -0.90 0.17 -0.02 -0.89 -0.80 -0.88 -0.29 -0.41
13721 || orf19.1124.2 || || || Ortholog(s) have diphthine synthase activity, role in peptidyl-diphthamide biosynthetic process from peptidyl-histidine and cytosol, nucleus localization || 1 -0.53 -0.42 -0.96 -0.65 0.40 0.14 -0.18 0.23 -1.06 0.09 0.14 -0.98 -0.61 -0.85 -0.44 -0.92
13722 || orf19.2720 || || || Cytosolic chaperonin Cct ring complex subunit; role in the assembly of actin and tubulins; Spider biofilm repressed || 1 -0.32 -0.51 -0.76 -0.75 0.42 -0.38 -0.38 0.33 -0.77 0.11 0.11 -0.71 -0.62 -0.13 -0.06 -0.25
13723 || orf19.1569 || UTP22 || || Putative U3 snoRNP protein; Ssr1-induced; repressed by prostaglandins; heterozygous null mutant is resistant to parnafungin || 1 -0.33 -0.15 -0.92 -0.73 0.04 -0.37 -0.27 -0.39 -1.01 0.78 -0.35 -1.03 -0.12 -0.62 -0.14 -1.14
13724 || orf19.3327 || TRM2 || || Putative tRNA methyltransferase; repressed by prostaglandins; Spider biofilm induced || 1 -0.57 -0.01 -0.80 -0.71 -0.57 -0.42 -0.35 -0.54 -0.69 0.71 -0.32 -0.88 -0.18 -0.12 -0.59 -0.88
13725 || orf19.7007 || || || Ortholog of C. dubliniensis CD36 : Cd36_70990 and Candida albicans WO-1 : CAWG_05464 || 1 -0.44 -0.22 -0.66 -0.40 -0.26 -0.23 -0.40 -0.50 -0.50 0.38 0.01 -0.42 -0.26 -0.36
13726 || orf19.3327 || TRM2 || || Putative tRNA methyltransferase; repressed by prostaglandins; Spider biofilm induced || 1 -0.50 -0.47 -0.93 -0.97 -0.42 -0.25 -0.37 -0.72 -0.60 0.70 -0.62 -0.66 -0.55 -0.18 -0.31 -0.54
13727 || orf19.665 || NEP1 || || Ortholog(s) have rRNA (pseudouridine) methyltransferase activity || 1 -0.57 -0.69 -1.29 -0.81 -0.62 -0.62 -0.53 0.03 -0.87 0.78 -0.41 -0.67 -0.60 -0.02 -0.23 -0.99
13728 || orf19.3034 || RLI1 || || Member of RNase L inhibitor (RLI) subfamily of ABC family; predicted not to be a transporter; regulated by Sef1p, Sfu1p, and Hap43p || 1 -0.41 -0.33 -0.99 -0.83 -0.43 -0.90 -0.44 -0.37 -0.74 0.63 -0.04 -0.29 -0.73 -1.08 -0.44 -1.26
13729 || orf19.4639 || || || Protein present in exponential and stationary growth phase yeast cultures || 1 -0.27 -0.11 -0.55 -0.55 -0.32 -0.52 -0.30 -0.04 -0.26 0.10 0.07 -0.23 -0.58 0.01 -0.22 -0.25
13730 || orf19.4639 || || || Protein present in exponential and stationary growth phase yeast cultures || 1 -0.50 -0.41 -0.77 -0.47 -0.36 -0.54 -0.35 -0.13 -0.47 0.02 0.08 -0.08 -0.75 0.04 -0.23 -0.43
13731 || orf19.1815 || || || Ortholog of S. cerevisae/S. pombe Tif6; constituent of 66S pre-ribosomal particles; Spider biofilm induced || 1 -0.39 -0.65 -1.07 -0.87 -0.75 -0.39 -0.06 -0.40 -0.49 0.16 -0.40 -0.64 -1.11 -0.14 -0.58 -0.60
13732 || orf19.875 || || || Protein required for respiratory growth || 1 -0.38 -0.38 -0.89 -0.86 -0.01 -0.12 -0.24 -0.13 -0.38 0.02 -0.24 -0.23 -0.95 -0.15 -0.31 -0.42
13733 || orf19.3556 || || || Transportin or cytosolic karyopherin beta; Spider biofilm induced || 1 -0.80 -0.81 -1.35 -1.49 -0.19 -0.23 -0.50 -0.39 -1.36 0.51 -0.29 -0.72 -0.76 -0.14 -0.47 -0.24
13734 || orf19.5885 || || || Putative U3 snoRNP protein; flucytosine induced || 1 -0.57 -0.67 -1.31 -1.07 -0.24 -0.39 -0.32 -0.07 -1.33 0.12 -0.37 -1.28 -0.84 -0.69 -1.22 -0.96
13735 || orf19.2017 || || || Ortholog(s) have RNA polymerase I activity and role in regulation of cell size, transcription elongation from RNA polymerase I promoter, transcription of nuclear large rRNA transcript from RNA polymerase I promoter || 1 -0.51 -0.43 -1.14 -1.17 -0.61 -0.29 -0.58 -0.05 -1.07 0.34 -0.16 -1.05 -0.62 -0.33 -1.06 -0.41
13736 || orf19.2017 || || || Ortholog(s) have RNA polymerase I activity and role in regulation of cell size, transcription elongation from RNA polymerase I promoter, transcription of nuclear large rRNA transcript from RNA polymerase I promoter || 1 -0.41 -0.29 -1.00 -0.93 -0.34 -0.24 -0.40 0.17 -0.89 0.59 0.10 -0.69 -0.59 -0.08 -0.62 -0.19
13737 || orf19.6417 || TSR1 || || Component of 20S pre-rRNA processing unit; repressed by prostaglandins || 1 -0.35 -0.46 -1.11 -1.34 -0.25 -0.20 -0.15 -0.23 -0.93 0.74 -0.12 -1.17 -0.47 0.21 -0.95 -0.24
13738 || orf19.6417 || TSR1 || || Component of 20S pre-rRNA processing unit; repressed by prostaglandins || 1 -0.46 -0.45 -1.20 -1.36 -0.12 -0.04 -0.16 -0.26 -0.83 0.74 -0.31 -1.25 -0.51 -0.13 -1.07 -0.60
13739 || orf19.5885 || || || Putative U3 snoRNP protein; flucytosine induced || 1 -0.40 -0.55 -1.14 -0.95 0.08 0.05 -0.13 0.09 -0.88 0.40 -0.06 -0.62 -0.87 -0.24 -0.81 -0.53
13740 || orf19.3564 || RPC40 || || Putative RNA polymerase; protein level decreases in stationary phase cultures; Hap43p-induced gene || 1 -0.55 -0.69 -1.33 -0.94 -0.21 0.14 0.11 0.45 -0.92 0.75 0.26 -0.76 -0.66 0.04 -0.94 -0.48
13741 || orf19.1839 || RPA190 || || Putative RNA polymerase I subunit A190; Hap43p-induced gene; flucytosine induced || 1 -0.34 -0.44 -0.81 -0.71 -0.43 -0.51 -0.23 0.52 -0.91 0.61 0.06 -0.84 -0.69 0.03 -0.65 0.07
13742 || orf19.506 || YDJ1 || || Putative type I HSP40 co-chaperone; heavy metal (cadmium) stress-induced || 1 -0.33 -0.52 -1.12 -0.87 -0.51 -0.77 -0.04 0.28 -0.84 0.75 0.22 -0.18 -0.41 0.09 -0.31 -0.46
13743 || orf19.3288 || NMA111 || || Putative serine protease and general molecular chaperone; macrophage-induced gene; repressed in core stress response; merged with orf19.3288.1 in Assembly 21 || 1 -0.31 -0.23 -1.15 -0.82 -0.45 -0.80 -0.05 0.25 -0.88 0.41 0.22 -0.56 -0.52 0.03 -0.35 0.13
13744 || orf19.3288.1 || || || Predicted ORF in Assembly 20 and 21; merged with orf19.3288 in Assembly 21 || 1 -0.45 -0.38 -1.10 -0.87 -0.67 -0.67 -0.00 0.16 -0.78 0.50 0.23 -0.62 -0.22 -0.08 -0.55 -0.17
13745 || orf19.1839 || RPA190 || || Putative RNA polymerase I subunit A190; Hap43p-induced gene; flucytosine induced || 1 -0.71 -0.89 -2.31 -1.55 -1.11 -1.36 -0.49 0.11 -1.57 0.20 -0.10 -1.35 -1.13 -0.38 -1.07 -0.35
13746 || orf19.3206 || CCT7 || || Cytosolic chaperonin Cct ring complex; protein is present in exponential and stationary growth phase yeast cultures; sumoylation target || 1 -0.69 -0.77 -1.57 -1.29 -0.52 -0.84 -0.11 0.15 -0.95 -0.01 0.22 -0.35 -0.53 -0.14 -0.52 -0.33
13747 || orf19.3206 || CCT7 || || Cytosolic chaperonin Cct ring complex; protein is present in exponential and stationary growth phase yeast cultures; sumoylation target || 1 -0.34 -0.40 -1.45 -1.11 -0.14 -0.70 -0.27 0.20 -0.61 0.25 0.34 -0.28 -0.33 0.23 -0.47 -0.14
13748 || orf19.6751 || || || Ortholog(s) have tRNA methyltransferase activity, role in cytoplasmic translation, tRNA methylation and cytoplasm localization || 1 -0.61 -0.11 -0.60 -1.12 -0.57 -0.57 0.07 -0.00 -0.78 0.32 -0.22 -0.52 0.11 0.22 -0.46 -0.47
13749 || orf19.4874 || MNN23 || || Alpha-1,2-mannosyltransferase; mutants hypersensitive to toxic ergosterol analog, amphotericin B, calcofluor white, growth at 42 degrees and have decreased cell wall mannan; flow model biofilm induced || 1 0.00 -0.08 -0.72 -0.35 0.01 -0.33 -0.32 -0.17 -0.75 -0.34 -0.00 -0.47 -0.16 0.17 -0.45 -0.32
13750 || orf19.4936 || || || Dubious open reading frame || 1 -0.49 -0.61 -2.51 -0.44 -0.18 -0.58 -0.34 -0.41 -0.95 -0.46 -1.26 -0.71 0.06 -0.06
13751 || orf19.5724 || || || Ortholog of C. parapsilosis CDC317 : CPAR2_500910, C. dubliniensis CD36 : Cd36_64110, Candida tenuis NRRL Y-1498 : CANTEDRAFT_115913 and Pichia stipitis Pignal : PICST_32870 || 1 -0.39 -0.44 -0.94 -0.22 -0.32 0.03 -2.17 -0.23 0.01 -1.01 -0.57 0.28 -0.35
13752 || orf19.6897 || || || Protein of unknown function || 1 -0.74 -0.25 -0.56 -0.29 0.03 0.02 -0.03 -0.28 -0.63 0.26 0.32 -0.56 -0.01 0.07 -0.12 -0.18
13753 || orf19.7069 || || || Putative AdoMet-dependent proline methyltransferase; Hap43-induced; required for normal flow model biofilm growth; Spider biofilm repressed || 1 -0.15 -0.30 -0.13 -0.30 -0.20 -0.11 -0.25 0.13 -0.73 0.25 -0.02 -0.79 -0.74 -0.15 -0.98 -0.45
13754 || orf19.5759 || SNQ2 || || Protein similar to S. cerevisiae Snq2p transporter; member of PDR subfamily of ABC family; transposon mutation affects filamentation; benomyl-induced transcription; detected at yeast-form cell plasma membrane by mass spec || 1 -0.94 -0.83 -0.73 0.00 -1.02 -0.33 -0.24 0.67 -1.38 -0.06 -0.80 -1.88 -1.55 0.78 -1.69 -0.42
13755 || orf19.5759 || SNQ2 || || Protein similar to S. cerevisiae Snq2p transporter; member of PDR subfamily of ABC family; transposon mutation affects filamentation; benomyl-induced transcription; detected at yeast-form cell plasma membrane by mass spec || 1 -0.58 -0.63 -0.21 0.41 -0.86 -0.17 -0.05 0.99 -1.07 0.19 -0.58 -1.46 -1.16 0.69 -1.53 -0.49
13756 || orf19.5257 || LCB4 || || Putative sphingosine kinase; Tac1p-regulated expression; rat catheter biofilm induced || 1 -0.48 -0.30 -0.27 -0.29 -0.41 -0.58 -0.15 -0.12 -0.38 -0.84 0.47 0.14 -0.31 0.15 -0.05 -0.47
13757 || orf19.2755 || || || Ortholog(s) have role in proteasomal ubiquitin-independent protein catabolic process, proteasome-mediated ubiquitin-dependent protein catabolic process and cytosol, nucleus, proteasome core complex, beta-subunit complex localization || 1 0.01 -0.13 -0.13 -0.03 -0.58 -0.61 0.04 0.12 -0.38 -0.17 0.24 -0.42 -0.18 -0.13 0.27 -0.03
13758 || orf19.1156 || FUS1 || || Membrane protein required for mating; ortholog of S. cerevisiae Fus1; transcript induced by Cph1 in cells homozygous for the MTLa locus; alpha factor induced || 1 0.15 -0.35 0.09 -0.52 -0.25 -0.17 -0.34 -0.86 -0.33 0.11 -0.37 0.55 -0.08
13759 || orf19.6403 || || || Ortholog(s) have adenyl-nucleotide exchange factor activity, role in SRP-dependent cotranslational protein targeting to membrane, translocation and endoplasmic reticulum localization || 1 -0.11 -0.25 -0.43 -0.46 -1.05 -0.68 -0.21 -0.19 -0.69 0.04 0.04 0.13 -0.23 0.11 0.60 -0.24
13760 || orf19.745 || VAC8 || || Protein involved in vacuolar inheritance; required for hyphal growth; contains armadillo repeats || 1 -0.14 -0.13 -0.43 -0.10 -0.43 -0.40 -0.25 -0.12 -0.62 -0.02 0.22 0.07 -0.24 0.18 0.45 0.18
13761 || orf19.1280 || SUI1 || || Putative translation initiation factor; flucytosine induced; genes encoding ribosomal subunits, translation factors, and tRNA synthetases are downregulated upon phagocytosis by murine macrophage || 1 -0.09 -0.20 -0.86 -0.28 -0.17 -0.55 -0.28 -0.12 -0.97 0.07 0.28 0.27 -0.12 0.17 0.84 -0.17
13762 || orf19.3886 || || || Ortholog of C. dubliniensis CD36 : Cd36_31820, C. parapsilosis CDC317 : CPAR2_205050, Debaryomyces hansenii CBS767 : DEHA2G10736g and Pichia stipitis Pignal : PICST_32993 || 1 0.03 -0.17 -0.83 -0.78 -0.25 -0.49 -0.24 -0.51 -1.08 -0.14 0.05 -0.09 0.34 -0.28 0.45 -0.08
13763 || orf19.1526 || SNF2 || || Protein involved in transcriptional regulation; ortholog of S. cerevisiae Snf2p, which is the catalytic subunit of the SWI/SNF chromatin remodeling complex; interacts with Swi1p; SWI/SNF complex is essential for hyphal growth and virulence || 1 -0.10 -0.07 -0.46 -0.39 -0.03 -0.22 -0.49 -0.07 -0.78 -0.19 0.52 -0.02 0.22 -0.05 0.12 -0.22
13764 || orf19.4946 || || || Ortholog of C. dubliniensis CD36 : Cd36_12240, C. parapsilosis CDC317 : CPAR2_801750, Candida tenuis NRRL Y-1498 : CANTEDRAFT_135403 and Pichia stipitis Pignal : PICST_29111 || 1 0.21 -0.75 -0.64 -0.96 -1.26 -1.11 0.01 -1.76 -0.14 0.62 -0.52 0.19 -0.25 -0.10 -0.34
13765 || orf19.3681 || || || Ortholog(s) have Ran guanyl-nucleotide exchange factor activity, protein transporter activity || 1 -0.26 -0.40 -0.00 0.04 -0.51 -0.50 -0.41 -0.08 -0.56 0.21 0.29 -0.23 -0.27 -0.26 -0.10 -0.44
13766 || orf19.7615 || || || Protein involved in endoplasmic reticulum (ER) to Golgi vesicle-mediated transport; putative subunit of the transport protein particle (TRAPP) complex of the cis-Golgi; Spider biofilm induced || 1 -0.62 -0.72 -0.42 -0.41 -0.70 -1.23 -0.86 -0.44 -0.69 0.34 -0.09 0.31 -0.05 -0.21 -0.18 -1.38
13767 || orf19.7615 || || || Protein involved in endoplasmic reticulum (ER) to Golgi vesicle-mediated transport; putative subunit of the transport protein particle (TRAPP) complex of the cis-Golgi; Spider biofilm induced || 1 -0.18 -0.07 -0.27 0.05 -0.08 -1.00 -0.47 0.08 -0.76 0.16 0.01 0.51 -0.04 -0.47 -0.12 -0.66
13768 || orf19.1279 || CDS1 || || Protein similar to S. cerevisiae Cds1p; transposon mutation affects filamentous growth || 1 -0.01 -0.41 -0.40 0.12 -0.23 -0.72 -0.37 0.27 -0.49 0.58 0.12 0.10 -0.63 -0.25 0.41 -0.45
13769 || orf19.6984 || || || Ortholog of C. dubliniensis CD36 : Cd36_85460, C. parapsilosis CDC317 : CPAR2_405760, Candida tenuis NRRL Y-1498 : CANTEDRAFT_116052 and Debaryomyces hansenii CBS767 : DEHA2D16940g || 1 0.30 -0.05 -0.39 0.02 -0.46 -0.72 -0.03 0.02 -0.29 0.45 -0.07 -0.34 0.06 -0.08 0.47 -0.40
13770 || orf19.6858 || EDC3 || || Ortholog(s) have role in cytoplasmic mRNA processing body assembly, deadenylation-independent decapping of nuclear-transcribed mRNA and cytoplasmic mRNA processing body localization || 1 -0.34 -0.10 -0.07 -0.12 -0.37 -0.56 -0.03 -0.02 0.05 0.47 0.17 0.47 -0.03 -0.28 0.25 -0.39
13771 || orf19.2036 || || || Predicted dihydrodiol dehydrogenase; ortholog of S. pombe SPAC513.06c; flow model and rat catheter biofilm repressed || 1 -0.16 -0.04 -0.17 0.12 -0.25 -0.72 -0.12 0.44 -0.17 0.50 0.62 0.49 0.35 -0.38 0.22 -0.43
13772 || orf19.7625 || PGA1 || || Putative GPI-anchored protein; induced during cell wall regeneration; required for normal adhesion to host cells and for adherence during Sabouraud biofilm formation; Spider biofilm induced || 1 -0.05 -0.29 -0.41 -0.33 -0.08 -0.54 -0.35 0.47 -0.31 0.49 0.81 0.35 -0.18 -0.57 0.73 -1.13
13773 || orf19.1299 || RPN6 || || Putative 26S proteasome subunit; Hap43p-induced gene; regulated by Gcn2p and Gcn4p || 1 0.17 0.25 -0.13 -0.23 0.33 -0.57 -0.13 0.44 -0.11 0.29 0.68 0.43 -0.07 -0.04 0.68 -0.46
13774 || orf19.1298 || NUP84 || || Ortholog(s) have structural constituent of nuclear pore activity || 1 0.07 0.14 -0.32 -0.27 0.02 -0.15 -0.25 -0.11 -0.30 0.10 0.28 0.25 0.22 -0.03 -0.00 -0.38
13775 || orf19.2212 || || || Ortholog of C. dubliniensis CD36 : Cd36_21980, Debaryomyces hansenii CBS767 : DEHA2F19734g, Pichia stipitis Pignal : psti_CGOB_00208 and Spathaspora passalidarum NRRL Y-27907 : spas_CGOB_00029 || 1 0.95 1.32 0.84 -0.61 -1.29 -0.09 0.35 0.48 -0.28 -0.07 0.89 0.63 0.12 -2.07
13776 || orf19.3885 || || || Has domain(s) with predicted N-acetyltransferase activity; highly induced during chlamydospore formation in both C. albicans and C. dubliniensis || 1 0.06 -0.31 0.59 0.31 -0.87 -0.87 -0.12 -0.34 0.46 -0.56 -0.47 0.67 -0.03 -0.04 -0.18 -1.12
13777 || orf19.6224 || || || RTA domain protein; predicted role in response to stress; Spider biofilm induced || 1 0.71 0.58 0.20 1.39 -2.33 -1.54 -0.31 -0.85 1.01 -0.37 -1.00 0.58 1.43 -1.21 -0.88
13778 || orf19.6734 || TCC1 || || Putative transcription factor/corepressor; regulation of filamentation and virulence; interacts with Tup1; regulates hypha-specific gene expression; contains 4 tetratricopeptide repeat (TPR) motifs; flucytosine repressed; Tbp1-induced || 1 0.12 0.12 0.52 0.60 -1.56 -1.32 0.36 -0.20 0.47 -0.37 -0.59 -0.03 0.84 -0.66 -0.42 -1.10
13779 || orf19.6734 || TCC1 || || Putative transcription factor/corepressor; regulation of filamentation and virulence; interacts with Tup1; regulates hypha-specific gene expression; contains 4 tetratricopeptide repeat (TPR) motifs; flucytosine repressed; Tbp1-induced || 1 0.40 0.43 0.95 0.92 -1.16 -0.91 0.37 -0.12 0.82 0.00 -0.43 0.14 0.93 -0.16 -0.28 -0.44
13780 || orf19.4056 || BRG1 || || Transcription factor; recruits Hda1 to hypha-specific promoters; Tn mutation affects filamentation; Hap43-repressed; Spider and flow model biofilm induced; required for Spider biofilm formation; Bcr1-repressed in RPMI a/a biofilms || 1 0.47 0.67 1.01 1.27 -3.36 -3.34 1.05 -1.10 0.69 0.71 -0.76 0.45 1.13 -0.01 1.72 -1.83
13781 || orf19.4056 || BRG1 || || Transcription factor; recruits Hda1 to hypha-specific promoters; Tn mutation affects filamentation; Hap43-repressed; Spider and flow model biofilm induced; required for Spider biofilm formation; Bcr1-repressed in RPMI a/a biofilms || 1 0.56 0.63 1.27 1.27 -3.37 -3.19 0.89 -1.25 0.64 0.43 -0.80 -0.00 1.18 -0.29 1.19 -1.88
13782 || orf19.4056 || BRG1 || || Transcription factor; recruits Hda1 to hypha-specific promoters; Tn mutation affects filamentation; Hap43-repressed; Spider and flow model biofilm induced; required for Spider biofilm formation; Bcr1-repressed in RPMI a/a biofilms || 1 0.40 0.44 1.26 1.29 -3.53 -2.96 0.71 -1.57 0.56 0.52 -1.12 0.24 1.07 -0.48 1.37 -1.69
13783 || orf19.4056 || BRG1 || || Transcription factor; recruits Hda1 to hypha-specific promoters; Tn mutation affects filamentation; Hap43-repressed; Spider and flow model biofilm induced; required for Spider biofilm formation; Bcr1-repressed in RPMI a/a biofilms || 1 0.24 0.25 0.83 0.82 -5.12 -4.36 0.78 -1.60 0.36 0.46 -1.11 -0.06 0.71 -0.47 1.31 -2.35
13784 || orf19.812 || || || Ortholog of C. dubliniensis CD36 : Cd36_18730, C. parapsilosis CDC317 : CPAR2_212510, Candida tenuis NRRL Y-1498 : CANTEDRAFT_135843 and Debaryomyces hansenii CBS767 : DEHA2D06732g || 1 -0.17 0.10 0.44 0.08 -1.10 -0.70 0.62 0.06 -0.44 0.34 0.13 0.83 0.09 0.36 -1.05
13785 || orf19.2180 || || || Ortholog(s) have calcium ion binding, zinc ion binding activity, role in axial cellular bud site selection, bipolar cellular bud site selection, regulation of COPII vesicle coating and cellular bud neck, cytosol, nucleus localization || 1 0.12 -0.29 0.23 0.19 -0.64 -0.19 -0.09 -0.18 -0.28 0.01 -0.26 -0.06 0.05 -0.55 0.36 -0.33
13786 || orf19.1439 || IPK1 || || Ortholog of S. cerevisiae/S. pombe Ipk1; an inositol pentakisphosphate 2-kinase, a nuclear protein required for synthesis of 1,2,3,4,5,6-hexakisphosphate; Spider biofilm induced || 1 -0.65 -0.49 -0.29 0.45 -1.40 -0.98 0.08 -0.79 -0.57 0.41 -0.16 0.26 0.45 -0.38 1.36 -0.27
13787 || orf19.1439 || IPK1 || || Ortholog of S. cerevisiae/S. pombe Ipk1; an inositol pentakisphosphate 2-kinase, a nuclear protein required for synthesis of 1,2,3,4,5,6-hexakisphosphate; Spider biofilm induced || 1 -0.57 -0.49 -0.42 0.34 -1.49 -1.13 0.13 -0.54 -0.60 0.26 -0.11 0.44 0.51 -0.03 1.39 -0.11
13788 || orf19.6264 || || || Ortholog of C. dubliniensis CD36 : Cd36_06080, C. parapsilosis CDC317 : CPAR2_803360, Candida tenuis NRRL Y-1498 : CANTEDRAFT_112428 and Debaryomyces hansenii CBS767 : DEHA2G15532g || 1 0.02 0.03 0.11 0.35 -0.22 -0.61 0.08 -0.07 -0.37 -0.05 -0.21 0.23 0.14 -0.20 0.06 -0.10
13789 || orf19.6227 || || || Ortholog of C. dubliniensis CD36 : Cd36_06390, C. parapsilosis CDC317 : CPAR2_209040, Candida tenuis NRRL Y-1498 : CANTEDRAFT_114052 and Debaryomyces hansenii CBS767 : DEHA2D14300g || 1 0.08 0.32 -0.12 0.40 -0.49 -0.64 -0.47 -0.40 -0.82 0.64 -0.31 0.30 0.70 -0.15 0.23 -0.47
13790 || orf19.4629 || || || Ortholog(s) have ubiquitin-ubiquitin ligase activity, role in mitochondrion inheritance, protein monoubiquitination, protein polyubiquitination and plasma membrane, ubiquitin ligase complex localization || 1 0.05 0.10 -1.10 -0.53 0.16 -1.64 -0.47 -0.56 -0.47 -0.60 -0.28 0.18 0.20 -0.19 -0.60 -0.54
13791 || orf19.3466 || || || Predicted methyltransferase; downregulated by fluphenazine treatment or in an azole-resistant strain that overexpresses CDR1 and CDR2 || 1 -0.28 -0.03 -0.14 -0.17 -0.15 -1.19 -0.17 -0.63 -0.77 -0.29 -0.05 0.25 0.18 -0.19 -0.24 -0.51
13792 || orf19.2539 || || || Protein of unknown function; transcript detected on high-resolution tiling arrays || 1 -0.12 0.03 0.17 -0.78 0.41 -1.18 -0.09 -0.49 -0.32 -0.30 -0.15 -0.03 -0.29 -0.37
13793 || orf19.5233 || || || Ortholog of Candida albicans WO-1 : CAWG_00211 || 1 0.30 0.26 -0.50 -0.68 0.22 -1.13 0.16 -0.26 0.13 -0.05 0.59 -1.05 0.40 0.05 -0.19
13794 || orf19.5284 || || || Dubious open reading frame || 1 -0.53 -0.22 -0.86 -1.18 0.38 -1.20 -0.33 0.05 0.28 0.07 0.31 -0.31 -0.28 -0.36 -0.23 0.30
13795 || orf19.1264 || CFL2 || || Oxidoreductase; iron utilization; Sfu1/Sef1/Hap43/Nrg1/Tup1/Rim101 regulated; alkaline/low iron/fluphenazine/ciclopirox olamine, flucytosine, fluconazole, Spider/flow model/rat catheter biofilm induced; caspofungin/amphotericin B repressed || 1 -0.37 -3.05 -4.57 -0.68 -5.00 -0.66 -0.71 -2.16 0.38 -1.57 0.70 -0.57 2.08
13796 || orf19.5796 || SHE9 || || Protein with similarity to S. cerevisiae She9p, which inhibits growth when overproduced; gene has possible growth-regulation element; fungal-specific (no human or murine homolog) || 1 -0.08 -0.12 -0.50 -1.17 -0.08 -1.06 -0.33 -0.04 -0.35 -0.26 0.00 -0.29 -0.10 -0.17 0.10 0.10
13797 || orf19.3345 || SIZ1 || || Possible SUMO/Smt3 ligase; Rim101-repressed || 1 0.13 0.06 -0.20 -0.23 -0.22 -0.30 -0.23 0.09 -0.08 -0.25 0.19 -0.23 -0.03 0.01 -0.07 0.17
13798 || orf19.2312 || || || Protein similar to ferric reductase Fre10p; possibly an essential gene, disruptants not obtained by UAU1 method || 1 -0.31 0.11 0.09 -0.15 -0.01 -1.66 -0.44 0.25 -0.08 -0.14 -0.07 0.05 -0.52 -0.63 -0.05 -0.25
13799 || orf19.4305 || || || Ortholog of C. dubliniensis CD36 : Cd36_52590, C. parapsilosis CDC317 : CPAR2_100565, Debaryomyces hansenii CBS767 : DEHA2G06908g and Candida guilliermondii ATCC 6260 : PGUG_02858 || 1 -0.37 -0.38 -0.54 -0.11 0.20 -2.77 -0.56 0.33 -0.19 -0.35 -0.11 -0.14 -0.32 -0.93 -0.14 0.43
13800 || orf19.6859 || || || Ortholog of C. dubliniensis CD36 : Cd36_44860, Candida tropicalis MYA-3404 : CTRG_04054 and Candida albicans WO-1 : CAWG_03295 || 1 -0.05 0.15 -0.95 -0.30 -0.11 -3.44 -0.74 -0.06 0.33 0.09 -0.22 0.50 -0.56 -0.52 0.26 1.00
13801 || orf19.1106 || || || Protein with Mob2p-dependent hyphal regulation; fluconazole-induced || 1 -0.14 0.82 0.17 0.33 -3.03 -0.05 -0.17 0.76 0.30 0.15 -0.66 -0.48 1.36
13802 || orf19.3719 || || || Dubious open reading frame || 1 -0.32 0.11 0.41 -0.29 0.56 -2.03 0.10 -0.47 0.62 0.54 0.53 0.50 0.04 -0.01 0.47
13803 || orf19.936 || || || Ortholog of C. dubliniensis CD36 : Cd36_50530, C. parapsilosis CDC317 : CPAR2_303990, Candida tenuis NRRL Y-1498 : CANTEDRAFT_107934 and Pichia stipitis Pignal : PICST_63283 || 1 -0.50 0.14 -0.24 -0.54 0.91 -3.29 0.13 -0.11 -0.02 0.24 0.66 0.83 -1.14 -0.05 -0.25
13804 || orf19.5057 || || || Ortholog of C. dubliniensis CD36 : Cd36_07380 and Candida albicans WO-1 : CAWG_00634 || 1 0.33 0.82 0.23 0.06 0.48 -3.40 0.46 -0.10 -0.22 0.83 -0.11 -0.38 0.56 -0.06 -0.70 -0.00
13805 || orf19.4579 || ERV29 || || Putative SURF4 family member; plasma membrane-localized; flow model biofilm repressed || 1 0.10 0.09 0.13 0.45 -0.37 -1.60 -0.45 -0.11 -0.28 0.12 -0.04 0.10 -0.06 0.11 -0.08 0.10
13806 || orf19.1737 || || || Ortholog of Candida albicans WO-1 : CAWG_01802 || 1 -0.61 -0.44 0.00 0.40 -1.10 -2.54 -0.19 -0.14 0.69 0.05 -0.33 0.61 -0.06 0.23 -0.16 0.50
13807 || orf19.410.3 || RIB4 || || Lumazine synthase (6,7-dimethyl-8-ribityllumazine synthase, DMRL synthase); catalyzes the penultimate step in the synthesis of riboflavin; Hap43-induced; rat catheter and Spider biofilm repressed || 1 -0.22 -0.32 -0.37 -0.59 -1.10 -0.18 -0.17 0.19 -0.01 0.14 0.35 -0.06 -0.03 0.01 0.40
13808 || orf19.759 || SEC21 || || Ortholog(s) have role in ER to Golgi vesicle-mediated transport, retrograde vesicle-mediated transport, Golgi to ER and COPI vesicle coat, cytosol, endosome localization || 1 -0.04 0.04 -0.10 -0.19 -0.02 -0.94 -0.33 0.01 -0.12 -0.09 0.21 0.10 0.17 0.12 0.05 0.13
13809 || orf19.1620 || || || Protein of unknown function; induced by alpha pheromone in SpiderM medium || 1 0.17 -0.02 0.34 -0.39 -0.19 -1.50 -0.19 0.36 -0.02 0.02 -0.15 0.41 0.26 0.11
13810 || orf19.3436 || || || Protein with a Rho GDP-dissociation inhibitor domain; macrophage-induced gene || 1 -0.33 -0.31 -0.14 -0.51 -0.29 -0.93 -0.16 0.02 0.24 -0.16 -0.08 0.04 0.24 0.51 -0.10 0.07
13811 || orf19.1400 || || || Ortholog of C. dubliniensis CD36 : Cd36_23640, C. parapsilosis CDC317 : CPAR2_406130, Candida tenuis NRRL Y-1498 : CANTEDRAFT_116273 and Debaryomyces hansenii CBS767 : DEHA2B11176g || 1 -0.06 -0.01 -0.25 -0.34 -0.22 -0.48 0.00 -0.13 0.23 0.07 0.00 0.15 0.04 0.16 0.27 0.01
13812 || orf19.1741 || DIT1 || || Ortholog(s) have catalytic activity and role in ascospore wall assembly || 1 -0.36 0.22 -0.30 -1.32 -0.20 0.05 -0.05 0.26 -0.11 0.63 0.62 -0.01
13813 || orf19.1366 || || || Has domain(s) with predicted oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors activity || 1 0.06 -0.10 -0.06 -1.56 0.12 -3.03 -0.06 0.10 0.41 -0.13 -0.59 0.59 0.06
13814 || orf19.4206 || || || Ortholog(s) have crossover junction endodeoxyribonuclease activity || 1 0.05 -0.06 -0.58 -1.12 0.03 -1.72 -0.05 0.21 -0.24 0.07 0.05 0.61 -0.42 1.08 0.11 0.70
13815 || orf19.2678 || BUB1 || || Putative cell cycle checkpoint kinase; mutation confers increased sensitivity to nocodazole || 1 -0.14 -0.11 0.00 -0.02 -0.03 -0.85 0.11 0.33 -0.23 -0.01 0.03 0.07 -0.27 0.20 -0.04 0.23
13816 || orf19.1238 || TUB4 || || Putative gamma-tubulin; induced upon adherence to polystyrene; transcript regulated by Nrg1 and Mig1; periodic mRNA expression, peak at cell-cycle S/G2 phase || 1 -0.00 -0.25 0.18 -0.06 0.48 -1.02 0.16 0.48 -0.18 0.09 0.18 0.32 0.06 0.03 -0.24 0.39
13817 || orf19.4950 || AKR1 || || Ankyrin-repeat protein; induced by fluphenazine || 1 0.08 -0.08 -0.17 0.14 -0.22 -0.58 0.61 0.20 -0.31 -0.47 0.41 -0.05 -0.12 0.11 0.34 0.20
13818 || orf19.6109 || TUP1 || || Transcriptional corepressor; represses filamentous growth; regulates switching; role in germ tube induction, farnesol response; in repression pathways with Nrg1, Rfg1; farnesol upregulated in biofilm; rat catheter, Spider biofilm repressed || 1 0.02 -0.16 -0.22 -0.04 -0.46 -0.50 0.71 0.56 -0.07 -0.31 0.76 -0.14 0.35 -0.25 0.29 -0.10
13819 || orf19.2473 || || || Putative RSC chromatin remodeling complex component; decreased transcription is observed upon fluphenazine treatment or in an azole-resistant strain that overexpresses CDR1 and CDR2 || 1 -0.22 0.21 -0.10 -0.32 -0.46 -0.63 0.05 0.64 0.02 -0.07 0.60 -0.05 0.22 0.16 0.22 0.08
13820 || orf19.6645 || HMO1 || || HMG-box transcription factor; binds upstream of hexose and ergosterol metabolism and cell cycle genes; activates pseudohyphal growth when expressed in S. cerevisiae; repressed in hyphae; Spider biofilm repressed || 1 -0.10 -0.20 -0.03 -0.01 -0.63 -0.98 -0.07 0.09 -0.25 -0.64 0.23 0.12 0.14 0.56 -0.32 0.36
13821 || orf19.3461 || || || Protein of unknown function; oxidative stress-induced via Cap1; induced by alpha pheromone in SpiderM medium || 1 0.02 0.02 0.27 0.33 -1.07 -2.30 0.25 0.23 -1.12 -1.23 0.79 -0.14 0.66 1.16 -0.14 1.53
13822 || orf19.4557 || || || Ortholog(s) have microtubule binding, structural constituent of cytoskeleton activity and role in microtubule nucleation, mitotic spindle assembly checkpoint, protein localization to kinetochore, sister chromatid biorientation || 1 0.30 0.67 -0.52 -0.34 -0.73 -1.45 -0.03 0.57 -0.62 -0.31 0.13 0.04 0.68 0.19 -0.40 0.39
13823 || orf19.6644 || || || Protein of unknown function; 2 predicted transmembrane domains; transcript detected on high-resolution tiling arrays; flow model biofilm induced; Spider biofilm repressed || 1 0.39 0.36 -0.07 -0.08 -0.08 -0.76 0.53 0.44 -0.58 -0.60 0.58 -0.22 0.37 0.12 -0.21 0.48
13824 || orf19.6644 || || || Protein of unknown function; 2 predicted transmembrane domains; transcript detected on high-resolution tiling arrays; flow model biofilm induced; Spider biofilm repressed || 1 0.26 0.30 -0.40 -0.30 -0.23 -0.80 0.55 0.35 -0.61 -0.61 0.50 -0.11 0.39 0.44 -0.11 0.66
13825 || orf19.6644 || || || Protein of unknown function; 2 predicted transmembrane domains; transcript detected on high-resolution tiling arrays; flow model biofilm induced; Spider biofilm repressed || 1 0.18 0.17 -0.32 -0.28 -0.31 -1.00 0.43 0.24 -0.40 -0.55 0.40 -0.30 0.41 0.11 -0.27 0.50
13826 || orf19.7506 || || || Ortholog(s) have ATPase activity, DNA binding, nucleosome binding activity, role in chromatin remodeling and Isw1 complex localization || 1 0.05 0.08 -0.30 -0.31 -0.06 -0.88 0.16 0.35 -0.14 -0.18 0.21 -0.30 0.20 0.00 -0.21 -0.02
13827 || orf19.5262 || || || Ortholog of C. dubliniensis CD36 : Cd36_11270 and Candida albicans WO-1 : CAWG_00238 || 1 -0.02 0.80 -0.80 -0.62 -2.34 0.59 1.24 0.00 -0.58 0.84 -0.39 1.33 0.15 0.14
13828 || orf19.4597 || || || Putative F-actin-capping protein subunit beta; possibly an essential gene, disruptants not obtained by UAU1 method || 1 0.19 0.08 -0.03 -0.19 -0.09 -0.58 0.32 0.37 0.01 -0.15 0.39 -0.40 0.47 0.01 -0.09 0.13
13829 || orf19.6358 || || || Ortholog(s) have protein homodimerization activity, ubiquitin-protein ligase activity and role in free ubiquitin chain polymerization, postreplication repair, protein K63-linked ubiquitination || 1 0.20 -0.07 -0.38 -0.21 -0.39 -0.81 0.36 0.45 -0.17 -0.34 0.37 -0.16 0.37 0.25 0.44 0.26
13830 || orf19.4715 || || || Ortholog(s) have tubulin binding activity, role in microtubule cytoskeleton organization, mitochondrial fission, mitochondrion inheritance, nuclear migration along microtubule and cell cortex, cellular bud tip, mitochondrion localization || 1 0.28 0.18 0.23 -0.09 -0.22 -0.52 0.10 0.22 -0.25 0.06 0.19 0.10 0.45 0.11 -0.00 0.39
13831 || orf19.69 || || || Protein of unknown function; induced by Mnl1 under weak acid stress || 1 0.69 1.11 0.02 -0.52 -0.94 -1.54 -0.22 0.52 0.59 0.23 0.51 -1.06 0.87 1.99 -0.31 0.58
13832 || orf19.69 || || || Protein of unknown function; induced by Mnl1 under weak acid stress || 1 0.65 0.53 -0.31 -1.63 -1.10 -2.55 0.25 0.13 0.31 -0.09 0.92 -0.60 0.81 1.40 -0.39 -0.41
13833 || orf19.225 || || || Predicted 2-hydroxyacid dehydrogenase; Hap43-repressed gene || 1 0.08 0.14 -0.34 -0.63 -0.78 -0.69 0.22 0.11 0.47 -0.31 0.21 -0.03 0.32 0.55 0.01 -0.23
13834 || orf19.4807 || || || Ortholog(s) have inorganic diphosphatase activity, role in aerobic respiration and mitochondrion localization || 1 0.09 0.19 -0.21 -0.23 -0.57 -0.72 0.21 0.29 0.31 -0.20 0.12 -0.34 -0.17 0.36 -0.08 0.19
13835 || orf19.4807 || || || Ortholog(s) have inorganic diphosphatase activity, role in aerobic respiration and mitochondrion localization || 1 0.12 0.22 -0.32 -0.35 -0.21 -0.66 0.37 0.27 0.17 -0.17 0.01 -0.44 0.09 0.50 -0.25 0.44
13836 || orf19.4892 || TPK1 || || cAMP-dependent protein kinase catalytic subunit; Tpk2 isoform; control of morphogenesis and stress response; WT nuclear localization requires Bcy1; produced during stationary, not exponential growth; rat catheter and Spider biofilm induced || 1 -0.02 0.32 -0.04 0.12 -0.68 -0.37 0.88 0.31 0.07 0.01 0.73 -0.22 0.73 0.59 -0.25 0.35
13837 || orf19.4290 || TRR1 || || Thioredoxin reductase; regulated by Tsa1/Tsa1B, Hap43; induced by nitric oxide, peroxide; oxidative stress-induce via Cap1; induced by human neutrophils; stationary phase enriched protein || 1 0.61 0.04 -0.38 -0.20 -0.36 -0.57 0.46 0.50 -0.09 -0.09 0.29 0.01 -0.29 0.24 -0.61 -0.14
13838 || orf19.3268 || TMA19 || || Cell wall protein, ortholog of S. cerevisiae Tma19p (Ykl065cp) || 1 0.17 0.09 -0.53 -0.18 -0.56 -0.41 0.40 0.46 -0.22 0.48 0.56 0.22 -0.63 -0.09 -0.64 0.07
13839 || orf19.3268 || TMA19 || || Cell wall protein, ortholog of S. cerevisiae Tma19p (Ykl065cp) || 1 0.23 0.18 -0.44 -0.22 -0.63 -0.58 0.23 0.38 -0.34 0.25 0.41 -0.22 -0.63 -0.13 -0.87 -0.03
13840 || orf19.4447 || YMC1 || || Putative inner mitochondrial membrane transporter; flucytosine induced; Spider biofilm repressed || 1 -0.03 -0.04 -0.60 0.10 -0.90 -0.49 0.28 0.75 -0.09 0.67 0.33 -0.02 -0.68 0.38 -1.28 -0.38
13841 || orf19.7009 || || || Has domain(s) with predicted catalytic activity, coenzyme binding activity and role in cellular metabolic process || 1 -0.37 -0.70 -0.49 -0.25 0.11 -0.74 0.75 0.52 0.10 0.25 -0.75 -0.49 -0.46 0.19 -0.56 -0.05
13842 || orf19.4995 || || || Ortholog of C. dubliniensis CD36 : Cd36_12580 || 1 -0.37 -0.58 0.04 -0.11 -0.62 -1.45 0.77 0.23 0.25 0.33 -0.65 -0.45 -0.19 0.63 -0.00 0.24
13843 || orf19.139 || TRA1 || || Subunit of the NuA4 histone acetyltransferase complex || 1 -0.36 -0.43 0.02 -0.01 -0.45 -0.77 -0.12 0.39 0.00 0.32 -0.12 -0.33 -0.14 0.46 -0.25 -0.05
13844 || orf19.4063 || GPT1 || || GABA/polyamine transporter; 9 to 11 membrane spanning segments; complements GABA uptake defect of an S. cerevisiae uga4 put4 gap1 triple mutant; complements growth of an S. cerevisiae spe1 mutant under polyamine limitation || 1 -0.26 -0.46 0.26 0.60 -0.42 -2.17 0.32 0.62 0.59 -0.01 -0.44 -1.13 0.01 -0.70 -0.76 0.48
13845 || orf19.4515 || || || Predicted protein with similarity to cell wall proteins; possibly an essential gene, disruptants not obtained by UAU1 method || 1 -0.26 -0.38 0.55 0.26 -0.31 -0.78 0.25 0.43 0.19 -0.59 -0.29 -0.25 0.03 0.26 -0.26 0.19
13846 || orf19.3061 || IMP1 || || Predicted subunit of the mitochondrial inner membrane peptidase complex involved in protein targeting to mitochondria || 1 0.04 0.00 0.09 0.02 -0.26 -0.51 0.63 0.40 0.07 -0.04 0.10 -0.34 -0.20 0.03 -0.37 0.07
13847 || orf19.6109 || TUP1 || || Transcriptional corepressor; represses filamentous growth; regulates switching; role in germ tube induction, farnesol response; in repression pathways with Nrg1, Rfg1; farnesol upregulated in biofilm; rat catheter, Spider biofilm repressed || 1 -0.32 -0.38 -0.25 0.14 -0.94 -0.78 0.51 0.47 -0.04 -0.27 0.17 -0.20 0.16 -0.21 -0.03 -0.42
13848 || orf19.5519 || GCV1 || || Putative T subunit of glycine decarboxylase; transcript negatively regulated by Sfu1; Spider biofilm repressed || 1 0.81 0.80 -1.02 -0.70 -1.57 -1.68 -0.12 -0.22 -0.36 -0.61 0.31 0.47 -0.73 -0.35 -0.47 0.11
13849 || orf19.1342 || SHM1 || || Mitochondrial serine hydroxymethyltransferase; complements the glycine auxotrophy of an S. cerevisiae shm1 null shm2 null gly1-1 triple mutant; protein present in exponential and stationary growth phase yeast cultures || 1 0.48 0.56 -0.86 -0.34 -1.33 -0.90 0.03 -0.06 -0.17 0.07 -0.25 -0.39 -0.77 0.28 -1.07 -0.02
13850 || orf19.56 || ARG2 || || Putative enzyme of arginine biosynthesis; transcription of genes of arginine biosynthesis pathway, except for ARG2, is induced upon phagocytosis by macrophage || 1 0.43 0.25 0.19 0.18 -0.22 -0.59 0.06 -0.24 0.15 -0.47 -0.37 -0.09 -0.50 0.19 -0.88 0.39
13851 || orf19.5253 || || || Has domain(s) with predicted ATP binding, protein tyrosine kinase activity and role in protein phosphorylation || 1 0.48 0.56 0.45 -0.02 -0.34 -0.77 0.11 0.05 0.42 -0.05 -0.61 -0.24 -0.32 0.28 -0.90 0.05
13852 || orf19.964 || SMC4 || || Ortholog(s) have chromatin binding activity and role in cellular protein localization, mitotic chromosome condensation, tRNA gene clustering || 1 0.44 0.29 0.21 -0.14 -0.29 -0.53 -0.01 0.49 -0.35 -0.01 0.14 -0.28 -0.00 0.29 -0.83 0.11
13853 || orf19.2774 || LAB5 || || Ortholog(s) have role in protein lipoylation and mitochondrion localization || 1 0.31 0.33 -0.07 -0.33 -0.73 -0.59 -0.15 0.16 -0.12 0.09 -0.37 -0.38 -0.05 0.37 -0.89 -0.20
13854 || orf19.250 || SLC1 || || Putative fatty acyltransferase; protein repressed during the mating process || 1 0.63 0.53 0.22 0.17 -1.67 -1.27 -0.05 0.41 -0.31 0.14 -0.61 -0.67 0.04 0.55 -1.85 -0.08
13855 || orf19.250 || SLC1 || || Putative fatty acyltransferase; protein repressed during the mating process || 1 1.03 0.76 0.09 -0.01 -1.60 -1.19 0.19 0.48 -0.50 0.02 -0.20 -0.64 0.26 0.74 -1.51 -0.49
13856 || orf19.2774 || LAB5 || || Ortholog(s) have role in protein lipoylation and mitochondrion localization || 1 0.66 0.56 0.08 -0.22 -0.57 -0.49 0.09 0.15 -0.16 0.14 -0.06 -0.49 0.19 0.13 -0.67 0.08
13857 || orf19.5838 || SER2 || || Ortholog(s) have phosphoserine phosphatase activity, role in L-serine biosynthetic process and cytoplasm, nucleus localization || 1 0.95 0.79 -0.09 0.17 -0.58 -0.71 0.22 0.48 0.00 0.32 0.08 -0.56 -0.28 0.26 -0.66 -0.40
13858 || orf19.7357 || || || Ortholog(s) have role in coenzyme A biosynthetic process and cytosol, nucleus localization || 1 0.76 0.45 -0.09 0.15 -0.82 -0.67 0.50 0.50 0.48 0.14 0.03 -0.25 -0.16 0.12 -0.78 -0.07
13859 || orf19.3411 || || || Ortholog(s) have role in cellular bud site selection and cytosol, nucleus localization || 1 0.44 0.43 0.57 0.44 -1.11 -0.83 0.27 0.34 0.15 0.17 -0.12 -0.63 0.04 0.47 -0.78 0.18
13860 || orf19.1946 || || || Similar to an aldose 1-epimerase-related protein; antigenic during murine systemic infection; protein present in exponential and stationary phase yeast cultures; Hap43-induced; Spider biofilm repressed || 1 0.81 0.72 0.31 0.40 -1.10 -0.38 0.36 0.13 -0.01 -0.41 0.03 -0.31 -0.10 0.33 -0.93 -0.19
13861 || orf19.6198.1 || || || Ortholog of S. cerevisiae : YIL156W-B, C. glabrata CBS138 : CAGL0H06732g, C. dubliniensis CD36 : Cd36_06600, C. parapsilosis CDC317 : CPAR2_208850 and Candida tenuis NRRL Y-1498 : CANTEDRAFT_116509 || 1 0.46 0.41 0.54 0.28 -0.60 -0.60 0.30 0.54 0.05 -0.15 0.13 -0.12 -0.05 0.63 -0.82 -0.22
13862 || orf19.5680 || || || Protein with predicted hydrolase domains; similar to a universal stress protein family protein; possibly essential, disruptants not obtained by UAU1 method; Spider biofilm repressed || 1 0.50 0.65 0.30 0.24 -0.71 -0.98 0.24 0.26 0.10 -0.07 0.25 -0.38 -0.38 0.05 -1.10 -0.09
13863 || orf19.1448 || APT1 || || Adenine phosphoribosyltransferase; flucytosine induced; repressed by nitric oxide; protein level decreased in stationary phase yeast cultures || 1 0.37 0.30 0.51 0.61 -1.15 -0.56 0.17 0.56 0.16 0.28 0.14 -0.40 -0.61 -0.10 -1.86 -0.39
13864 || orf19.1448 || APT1 || || Adenine phosphoribosyltransferase; flucytosine induced; repressed by nitric oxide; protein level decreased in stationary phase yeast cultures || 1 0.62 0.70 0.48 0.46 -0.62 -0.20 0.12 0.35 0.05 0.22 0.16 0.02 -0.19 0.11 -1.46 0.03
13865 || orf19.5838 || SER2 || || Ortholog(s) have phosphoserine phosphatase activity, role in L-serine biosynthetic process and cytoplasm, nucleus localization || 1 0.93 0.83 0.37 0.59 -0.91 -0.67 0.14 0.49 0.28 0.40 -0.26 -0.14 -0.43 0.44 -1.29 -0.30
13866 || orf19.5019 || || || Ortholog of C. dubliniensis CD36 : Cd36_12800, C. parapsilosis CDC317 : CPAR2_203460, Candida tenuis NRRL Y-1498 : CANTEDRAFT_94106 and Debaryomyces hansenii CBS767 : DEHA2C13948g || 1 0.28 0.35 0.41 0.53 -0.63 -0.47 0.03 0.24 -0.08 0.16 -0.28 -0.80 -0.28 0.39 -1.31 -0.47
13867 || orf19.2246 || || || Ortholog(s) have cytosol, nucleus localization || 1 1.58 1.45 0.56 1.09 -0.88 -0.72 0.61 1.11 -0.11 0.38 -0.03 -0.48 0.53 0.68 -1.77 -0.38
13868 || orf19.7043 || || || Ortholog(s) have endoplasmic reticulum localization || 1 1.54 1.52 0.59 0.44 -0.63 -0.59 0.32 0.39 -0.07 -0.01 -0.14 -0.53 0.22 0.19 -0.90 -0.19
13869 || orf19.7357 || || || Ortholog(s) have role in coenzyme A biosynthetic process and cytosol, nucleus localization || 1 0.61 0.76 0.28 0.42 -0.76 -0.60 0.49 0.47 0.57 0.27 0.17 0.38 -0.06 0.38 -0.45 -0.54
13870 || orf19.837 || GNA1 || || Glucosamine-6-phosphate acetyltransferase; enzyme of UDP-GlcNAc biosynthesis; required for viability in absence of GlcNAc supplementation; required for persistent infection and wild-type virulence in mouse systemic infection || 1 0.58 0.74 0.02 0.17 -0.59 -1.06 -0.17 0.10 0.15 0.36 0.04 0.35 -0.09 0.55 -0.82 -0.32
13871 || orf19.1282 || CKS1 || || Ortholog(s) have histone binding, protein complex binding, protein homodimerization activity, protein kinase activator activity, ubiquitin binding activity || 1 0.96 0.79 -0.11 -0.27 -1.54 -1.42 0.51 0.70 0.37 0.66 0.39 0.41 0.15 0.36 -1.18 -0.59
13872 || orf19.1342 || SHM1 || || Mitochondrial serine hydroxymethyltransferase; complements the glycine auxotrophy of an S. cerevisiae shm1 null shm2 null gly1-1 triple mutant; protein present in exponential and stationary growth phase yeast cultures || 1 0.68 0.65 -0.55 -0.09 -0.88 -0.55 0.20 0.21 0.26 0.40 -0.05 0.27 -0.29 0.65 -0.94 -0.03
13873 || orf19.6220.3 || MMD1 || || Mitochondrial protein; possibly required for transamination of isoleucine; macrophage-downregulated protein abundance; rat catheter and Spider biofilm repressed || 1 0.80 0.76 -0.21 -0.09 -0.97 -0.91 0.44 0.23 -0.25 -0.18 0.26 -0.17 0.28 -0.28 -0.28 0.04
13874 || orf19.2068 || || || Ortholog of C. dubliniensis CD36 : Cd36_15550, C. parapsilosis CDC317 : CPAR2_213190, Candida tenuis NRRL Y-1498 : CANTEDRAFT_119026 and Debaryomyces hansenii CBS767 : DEHA2G08514g || 1 0.66 0.35 0.04 0.29 -0.33 -0.88 0.30 0.21 0.19 -0.00 0.10 -0.24 -0.06 -0.29 -0.34 0.05
13875 || orf19.3667 || || || Ortholog(s) have microtubule motor activity, protein homodimerization activity and kinesin complex localization || 1 0.39 0.30 -0.03 -0.11 -0.86 -1.43 0.46 -0.05 0.84 0.02 0.11 -0.45 0.46 -0.33 -0.38 -0.07
13876 || orf19.3996 || || || Putative mannosyltransferase; similar to S. cerevisiae Gpi10p; has HKEXRF motif || 1 0.14 0.15 0.04 0.08 -0.67 -0.61 0.11 0.10 0.18 0.09 0.17 -0.34 -0.09 -0.55 -0.46 -0.00
13877 || orf19.6630 || || || Ortholog(s) have role in ER-associated ubiquitin-dependent protein catabolic process || 1 0.30 0.19 0.39 0.29 -0.90 -0.76 0.24 0.60 0.51 -0.06 0.16 -0.20 -0.52 -0.84 -0.08 -0.14
13878 || orf19.6630 || || || Ortholog(s) have role in ER-associated ubiquitin-dependent protein catabolic process || 1 0.52 0.37 0.31 0.23 -1.39 -0.98 0.20 0.50 -0.00 -0.10 0.44 -0.29 -0.61 -0.77 -0.07 -0.08
13879 || orf19.6630 || || || Ortholog(s) have role in ER-associated ubiquitin-dependent protein catabolic process || 1 0.42 0.41 0.31 0.14 -1.10 -0.72 0.19 0.59 -0.01 -0.09 0.45 -0.11 -0.62 -0.56 -0.01 -0.08
13880 || orf19.6630 || || || Ortholog(s) have role in ER-associated ubiquitin-dependent protein catabolic process || 1 0.02 0.40 0.16 0.19 -1.04 -0.85 0.29 0.56 -0.04 0.06 0.54 -0.04 -0.56 -0.71 -0.09 -0.25
13881 || orf19.3411 || || || Ortholog(s) have role in cellular bud site selection and cytosol, nucleus localization || 1 0.21 0.02 0.32 0.35 -0.85 -0.68 0.02 0.22 -0.05 -0.07 0.73 0.02 -0.38 0.01 0.08 0.29
13882 || orf19.1180 || || || Putative 2-aminoadipate transaminase; rat catheter and Spider biofilm repressed || 1 -0.23 -0.20 0.23 0.10 -0.59 -0.62 -0.08 0.05 0.46 -0.11 -0.18 -0.17 -0.31 0.02 -0.51 -0.09
13883 || orf19.6180 || || || Protein similar to Pichia anomala YDL054c and S. cerevisiae Ydl054cp; transmembrane regions predicted; Hap43p-repressed gene || 1 -0.57 -0.64 0.08 -0.03 -0.79 -1.04 -0.19 0.07 0.62 -0.08 -0.34 -0.38 -0.15 -0.28 -0.58 -0.63
13884 || orf19.6531 || NUC2 || || Putative NADH-ubiquinone oxidoreductase; identified in detergent-resistant membrane fraction (possible lipid raft component); alkaline repressed; Hap43-repressed; Spider biofilm repressed || 1 0.22 0.13 -0.28 -0.12 -0.85 -0.44 0.34 0.42 0.31 0.72 -0.57 -0.16 -0.82 -0.27 -0.38 -0.83
13885 || orf19.1710 || ALI1 || || Putative NADH-ubiquinone oxidoreductase; in detergent-resistant membrane fraction (possible lipid raft component); predicted N-terminal acetylation; nitric oxide-repressed; plasma membrane-localized; protein decreases in stationary phase || 1 0.21 0.01 -0.41 -0.32 -1.16 -0.73 0.43 0.44 0.24 0.63 -0.37 -0.01 -1.05 -0.23 -0.55 -0.54
13886 || orf19.5893 || RIP1 || || Putative ubiquinol cytochrome c-reductase; induced by high iron; Hap43, nitric oxide, alkaline repressed; Spider biofilm repressed || 1 -0.01 0.00 -0.32 -0.34 -1.17 -0.83 0.95 0.77 0.22 0.31 -0.13 -0.25 -0.62 -0.25 -0.38 -0.41
13887 || orf19.2954 || || || Protein of unknown function; Hap43-repressed gene; repressed by nitric oxide || 1 0.22 0.19 -0.50 -0.44 -0.62 -0.41 0.71 0.77 0.28 0.52 -0.10 -0.42 -0.63 -0.08 -0.34 -0.31
13888 || orf19.1872 || || || Plasma membrane protein; repressed by nitric oxide || 1 0.22 0.14 -0.50 -0.32 -0.62 -0.56 0.38 0.60 0.09 0.34 -0.19 -0.43 -0.59 -0.49 -0.43 -0.52
13889 || orf19.2952 || EXG2 || || GPI-anchored cell wall protein, similar to S. cerevisiae exo-1,3-beta-glucosidase Exg2p; predicted Kex2p substrate; induced during cell wall regeneration; possibly an essential gene, disruptants not obtained by UAU1 method; Hap43p-repressed || 1 -0.02 -0.24 -1.20 -0.45 -2.56 -3.42 1.08 0.88 1.07 0.98 0.14 -0.49 -1.99 -0.93 -2.27 -0.98
13890 || orf19.2952 || EXG2 || || GPI-anchored cell wall protein, similar to S. cerevisiae exo-1,3-beta-glucosidase Exg2p; predicted Kex2p substrate; induced during cell wall regeneration; possibly an essential gene, disruptants not obtained by UAU1 method; Hap43p-repressed || 1 -0.06 -0.50 -1.00 -0.70 -2.90 -3.17 1.18 1.11 1.12 1.03 0.12 -0.10 -2.16 -0.73 -2.19 -0.87
13891 || orf19.4016 || || || Putative ubiquinol-cytochrome-c reductase; amphotericin B induced; repressed by nitric oxide; protein level decreases in stationary phase cultures; Hap43-repressed; Spider biofilm repressed || 1 -0.10 -0.28 -0.40 -0.35 -1.16 -0.97 0.80 0.83 0.63 0.68 -0.54 -0.47 -0.67 0.05 -0.97 -0.30
13892 || orf19.3065 || DAO1 || || Putative D-amino acid oxidase; transcription is regulated upon yeast-hyphal switch || 1 -0.19 -0.19 -0.30 -0.07 -1.14 -1.17 0.56 0.58 0.66 0.24 -0.31 -0.24 -0.36 0.11 -0.83 -0.46
13893 || orf19.898 || HEM2 || || Putative porphobilinogen synthase; induced in high iron; protein level decrease in stationary phase cultures; Spider biofilm repressed || 1 -0.46 -0.38 -0.70 -0.12 -1.29 -1.82 0.76 1.05 0.94 0.62 -0.26 -0.29 -0.89 0.36 -1.01 -0.41
13894 || orf19.898 || HEM2 || || Putative porphobilinogen synthase; induced in high iron; protein level decrease in stationary phase cultures; Spider biofilm repressed || 1 -0.25 -0.28 -0.27 -0.13 -0.70 -1.00 0.50 0.60 0.83 0.41 -0.37 -0.00 -0.54 0.26 -0.77 -0.17
13895 || orf19.1394 || || || Putative protein of unknown function; mutant is viable; protein level decreases in stationary phase cultures; Spider biofilm induced || 1 -0.13 -0.14 -0.25 0.02 -0.74 -0.58 0.50 0.41 0.62 0.33 0.14 -0.10 -0.34 0.04 -0.60 -0.44
13896 || orf19.2951 || HOM6 || || Putative homoserine dehydrogenase; Gcn4-regulated; induced by amino acid starvation (3-ATtreatment); macrophage-induced protein; protein level decreases in stationary phase cultures; flow model biofilm repressed || 1 -0.38 -0.73 -0.35 0.02 -1.49 -1.45 0.99 1.10 0.81 0.31 0.08 -0.27 -0.37 -0.18 -0.88 -0.55
13897 || orf19.1789.1 || LYS1 || || Saccharopine dehydrogenase (biosynthetic); enzyme of alpha-aminoadipate lysine biosynthesis pathway; functionally complements S. cerevisiae lys1 mutation; fungal-specific (no human or murine homolog) || 1 -0.09 0.00 -0.19 0.43 -1.09 -0.82 0.72 0.80 0.42 0.01 -0.50 -0.23 -0.92 0.01 -0.80 -0.41
13898 || orf19.6607 || || || Ortholog(s) have role in mitochondrial respiratory chain complex I assembly and mitochondrial membrane localization || 1 0.05 0.19 -0.71 -0.09 -1.23 -0.51 0.40 0.45 -0.01 0.26 -0.09 -0.27 -0.05 -0.00 -0.56 -0.18
13899 || orf19.5379 || ERG4 || || Protein similar to sterol C-24 reductase; shows Mob2p-dependent hyphal regulation; fluconazole-induced; caspofungin repressed; rat catheter biofilm repressed || 1 0.45 0.42 0.57 0.83 -1.12 -1.38 0.38 0.81 0.27 0.06 0.57 -0.28 -0.02 -0.13 -0.99 -0.59
13900 || orf19.7398.1 || TSA1B || || Putative peroxidase; orf19.7398.1 is contig-truncated fragment of gene identical to TSA1; Tsa1p and Tsa1Bp role under oxidative/reductive stress, hyphal cell wall formation; in hyphal nucleus, cell wall; yeast-form nucleus, cytoplasm || 1 -0.06 -0.10 0.57 0.93 -1.24 -1.12 0.26 0.25 0.24 -0.37 0.35 -0.17 0.16 0.01 -1.26 -0.46
13901 || orf19.7398.1 || TSA1B || || Putative peroxidase; orf19.7398.1 is contig-truncated fragment of gene identical to TSA1; Tsa1p and Tsa1Bp role under oxidative/reductive stress, hyphal cell wall formation; in hyphal nucleus, cell wall; yeast-form nucleus, cytoplasm || 1 0.02 -0.09 0.42 0.82 -1.20 -1.04 0.28 0.21 0.27 -0.17 0.05 -0.19 0.01 0.08 -1.17 -0.48
13902 || orf19.3014 || BMH1 || || Sole 14-3-3 protein in C. albicans; role in hyphal growth; possibly regulated by host interaction; localizes to yeast-form cell surface, not hyphae; alternatively spliced 5' UTR intron; Spider biofilm repressed || 1 -0.11 -0.23 0.23 0.56 -1.40 -0.83 -0.02 0.02 0.34 -0.08 0.03 -0.06 0.03 -0.15 -0.44 -0.03
13903 || orf19.5363 || || || Component of UDP-GlcNAc transferase; required for the 2nd step of dolichyl-linked oligosaccharide synthesis; Spider biofilm induced || 1 0.01 0.14 0.18 0.23 -0.71 -0.95 0.02 0.23 0.10 -0.11 -0.04 -0.38 -0.06 -0.02 -0.13 -0.25
13904 || orf19.5645 || MET15 || || O-acetylhomoserine O-acetylserine sulfhydrylase; sulfur amino acid synthesis; immunogenic; Hog1, adherence-induced; brown color of mutant in Pb(2+) medium a visual selection; chlamydospore formation induced, F-12/CO2 biofilm induced || 1 0.08 -0.03 0.97 1.73 -2.91 -2.06 0.13 0.03 -0.41 -0.46 -0.30 -0.34 -0.24 -0.66 -0.37 -1.05
13905 || orf19.5645 || MET15 || || O-acetylhomoserine O-acetylserine sulfhydrylase; sulfur amino acid synthesis; immunogenic; Hog1, adherence-induced; brown color of mutant in Pb(2+) medium a visual selection; chlamydospore formation induced, F-12/CO2 biofilm induced || 1 0.14 0.13 0.91 1.61 -2.12 -1.88 -0.06 -0.14 -0.70 -0.73 -0.30 -0.41 -0.08 -0.73 -0.46 -0.76
13906 || orf19.3946 || || || Ortholog(s) have membrane insertase activity, role in protein insertion into mitochondrial membrane from inner side, respiratory chain complex IV assembly and integral to mitochondrial inner membrane localization || 1 0.29 0.23 0.22 0.41 -0.65 -0.99 -0.05 -0.07 -0.16 -0.14 -0.01 0.10 -0.14 -0.17 -0.09 -0.53
13907 || orf19.4181 || SPC2 || || Signal peptidase complex component; role in ER protein translocation; transcript is induced upon filamentous growth || 1 0.32 0.20 0.07 -0.15 -1.12 -1.11 -0.38 0.25 -0.64 -0.31 0.08 -0.59 -0.36 -0.36 -0.19 -0.43
13908 || orf19.2245 || YPT72 || || Vacuolar Rab small monomeric GTPase involved in vacuolar biogenesis; involved in filamentous growth and virulence || 1 0.28 0.16 -0.29 -0.28 -1.47 -1.62 -0.53 -0.05 -0.77 -0.16 -0.24 -0.80 -0.25 -0.11 -0.59 -0.40
13909 || orf19.3259 || || || Ortholog(s) have peptidase activity, role in protein targeting to ER, signal peptide processing and signal peptidase complex localization || 1 0.20 0.12 -0.12 -0.03 -0.85 -1.17 -0.01 0.06 -0.62 0.00 -0.31 -0.56 -0.47 -0.18 -0.31 -0.25
13910 || orf19.1186 || || || Has domain(s) with predicted role in attachment of GPI anchor to protein and GPI-anchor transamidase complex localization || 1 0.45 0.36 -0.01 0.03 -1.29 -1.76 -0.42 -0.11 -0.80 0.00 -0.76 -0.96 -0.71 -0.78 -0.63 -0.50
13911 || orf19.3135 || || || Ortholog(s) have protein binding, bridging activity and role in ER-associated ubiquitin-dependent protein catabolic process, lipid particle organization || 1 0.29 0.32 -0.40 -0.33 -0.79 -0.78 -0.29 0.04 -0.16 -0.07 -0.30 -0.45 -0.37 -0.21 -0.24 0.11
13912 || orf19.7632 || || || Ortholog of C. dubliniensis CD36 : Cd36_35360, C. parapsilosis CDC317 : CPAR2_200320, Candida tenuis NRRL Y-1498 : CANTEDRAFT_136418 and Debaryomyces hansenii CBS767 : DEHA2A14080g || 1 -0.03 0.11 0.07 -0.12 -0.76 -1.00 -0.39 0.48 -0.03 0.32 -0.38 -0.22 -0.57 -0.09 -0.75 -0.03
13913 || orf19.6327 || HET1 || || Putative sphingolipid transfer protein; involved in localization of glucosylceramide which is important for virulence; Spider biofilm repressed || 1 -0.37 -0.48 0.00 0.15 -1.61 -0.90 -0.33 -0.14 -0.51 -0.03 -0.11 0.35 -1.03 -0.58 -0.53 0.26
13914 || orf19.3409 || SEC12 || || Putative guanyl-nucleotide exchange factor; induced in high iron; Hap43-repressed || 1 -0.22 -0.30 -0.16 -0.01 -0.98 -0.97 -0.15 0.11 -0.34 -0.04 -0.12 -0.24 -0.76 -0.38 -0.47 0.15
13915 || orf19.5073 || DPM1 || || Putative dolichol phosphate mannose synthase; filament induced; Tup1-regulated; flow model and rat catheter biofilm repressed || 1 -0.17 -0.30 0.19 0.45 -0.85 -0.72 -0.31 0.17 -0.29 0.16 0.10 -0.07 -0.86 -0.16 -0.58 -0.05
13916 || orf19.6327 || HET1 || || Putative sphingolipid transfer protein; involved in localization of glucosylceramide which is important for virulence; Spider biofilm repressed || 1 -0.02 -0.22 0.44 0.56 -1.43 -0.85 -0.26 -0.10 -0.21 0.06 0.05 -0.03 -0.72 -0.75 -0.77 -0.36
13917 || orf19.6176 || SEC61 || || ER protein-translocation complex subunit; essential; 10 predicted transmembrane regions; chimeric mutant partially functionally complements S. cerevisiae sec61 defects; Spider biofilm repressed || 1 -0.39 -0.44 0.28 0.52 -1.68 -1.41 -0.37 -0.10 -0.49 -0.10 -0.13 -0.38 -0.35 -0.50 -0.28 0.05
13918 || orf19.6176 || SEC61 || || ER protein-translocation complex subunit; essential; 10 predicted transmembrane regions; chimeric mutant partially functionally complements S. cerevisiae sec61 defects; Spider biofilm repressed || 1 -0.41 -0.45 0.19 0.02 -1.29 -1.27 -0.14 0.14 -0.37 0.30 0.20 0.06 -0.12 -0.25 -0.21 0.28
13919 || orf19.3994 || || || Dolichyl-diphosphooligosaccharide-protein glycotransferase; predicted role in protein N-linked glycosylation, protein O-linked mannosylation; Spider biofilm repressed || 1 0.07 -0.17 0.26 0.30 -0.82 -1.18 0.10 0.28 0.02 0.09 -0.20 -0.02 -0.50 -0.49 -0.32 -0.17
13920 || orf19.6496 || TRS33 || || Putative TRAPP complex subunit; constitutive expression independent of MTL or white-opaque status || 1 0.24 0.21 0.10 0.42 -1.51 -1.27 -0.27 -0.07 0.00 0.49 -0.28 -0.14 -0.47 -0.38 -0.37 -0.05
13921 || orf19.6247 || || || Ortholog(s) have chromatin binding activity || 1 -0.67 -0.28 0.02 0.51 -0.95 -1.57 -0.36 0.30 -0.02 0.82 0.58 0.06 -0.45 -0.09 -0.54 0.14
13922 || orf19.7413 || MMS21 || || Putative MMS21-SMC5-SMC6 complex component || 1 -0.56 -0.53 0.04 -0.08 -0.82 -1.28 -0.13 0.35 0.28 0.84 0.12 0.20 -0.80 -0.14 -0.62 -0.10
13923 || orf19.641 || || || Ortholog(s) have role in protein folding and endoplasmic reticulum localization || 1 -0.22 -0.28 -0.38 -0.03 -0.83 -1.10 0.02 0.35 -0.14 0.98 0.31 0.10 -0.76 -0.09 -0.37 -0.17
13924 || orf19.3468 || ALG11 || || Alpha-1,2-mannosyltransferase; catalyzes sequential addition of 2 terminal alpha 1,2-mannose residues to the Man5GlcNAc2-PP-dolichol intermediate during asparagine-linked glycosylation in the ER; Spider biofilm induced || 1 -0.13 -0.24 -0.29 -0.00 -1.00 -1.43 -0.18 0.09 -0.78 1.03 -0.07 -0.06 -0.25 -0.04 -0.58 -0.18
13925 || orf19.3761 || CDC54 || || Putative pre-replication complex helicase subunit; transcript regulated by Nrg1 and Mig1; periodic mRNA expression, peak at cell-cycle M/G1 phase; Hap43-induced || 1 -0.44 -0.54 -0.20 0.27 -1.18 -2.53 -0.35 -0.02 -0.16 0.97 0.55 0.04 -0.06 -0.17 -1.15 -0.71
13926 || orf19.7413 || MMS21 || || Putative MMS21-SMC5-SMC6 complex component || 1 -0.82 -0.86 -0.47 -0.03 -0.80 -2.02 -0.01 0.14 -0.33 0.76 0.42 0.01 -0.79 -0.28 -1.13 -0.56
13927 || orf19.3468 || ALG11 || || Alpha-1,2-mannosyltransferase; catalyzes sequential addition of 2 terminal alpha 1,2-mannose residues to the Man5GlcNAc2-PP-dolichol intermediate during asparagine-linked glycosylation in the ER; Spider biofilm induced || 1 -0.36 -0.55 -0.41 0.08 -1.20 -1.78 -0.46 -0.24 -0.40 0.83 -0.10 -0.29 -0.65 -0.34 -0.90 -0.62
13928 || orf19.3468 || ALG11 || || Alpha-1,2-mannosyltransferase; catalyzes sequential addition of 2 terminal alpha 1,2-mannose residues to the Man5GlcNAc2-PP-dolichol intermediate during asparagine-linked glycosylation in the ER; Spider biofilm induced || 1 -0.22 -0.34 -0.51 0.07 -1.20 -1.81 -0.92 -0.22 -0.55 0.54 0.05 -0.13 -0.51 -0.71 -0.88 -0.17
13929 || orf19.676 || || || Microtubule-binding protein of the cortical microtubule; delays exit from mitosis when the spindle is abnormally oriented; Spider biofilm repressed || 1 -0.24 -0.25 -0.39 0.47 -0.65 -1.48 -0.35 0.22 -0.14 0.71 -0.19 0.11 -0.26 -0.71 -0.43 -0.33
13930 || orf19.7327 || PHO88 || || Protein with a role in phosphate transport; biofilm-regulated expression; amphotericin B repressed || 1 -0.25 -0.24 -0.20 0.47 -0.61 -1.32 -0.59 -0.02 -0.23 0.51 -0.16 0.06 -0.27 -0.32 -0.05 -0.56
13931 || orf19.4064 || GPI7 || || Protein involved in attachment of GPI-linked proteins to cell wall; member of major facilitator superfamily; phosphodiesterase/nucleotide pyrophosphatase domain; similar to S. cerevisiae Gpi7p || 1 -0.02 -0.19 0.20 0.95 -0.68 -1.41 -0.25 0.59 0.59 0.50 -0.66 -0.75 -0.29 -0.15 -0.81 -0.94
13932 || orf19.4765 || PGA6 || || GPI-anchored cell wall adhesin-like protein; induced by high iron; upregulated upon Als2 depletion; mRNA binds She3 and is localized to hyphal tips; Spider biofilm repressed || 1 -0.10 -0.17 0.14 0.45 -0.99 -2.09 -0.11 0.33 0.38 0.86 -0.54 -1.10 0.23 -0.20 -1.19 -0.76
13933 || orf19.5138 || IFA21 || || IPF family A protein; mutants are viable; Spider biofilm induced || 1 -0.36 -0.35 0.22 0.17 -0.69 -1.08 0.07 0.12 -0.23 0.55 -0.73 -0.53 -0.30 0.38 -0.35 -0.62
13934 || orf19.2599 || CRC1 || || Mitochondrial carnitine carrier protein || 1 -0.41 -0.43 -0.28 0.14 -1.17 -1.54 -0.14 0.23 -0.09 0.72 -0.84 -0.57 -0.83 -0.04 -0.40 -0.91
13935 || orf19.6219 || || || Ortholog of C. dubliniensis CD36 : Cd36_06470, C. parapsilosis CDC317 : CPAR2_208960, Candida tenuis NRRL Y-1498 : CANTEDRAFT_114040 and Pichia stipitis Pignal : PICST_51125 || 1 -0.43 -0.37 0.06 0.01 -0.77 -1.67 -0.12 0.29 0.05 0.20 -0.45 -0.66 -0.19 0.07 -0.50 -0.76
13936 || orf19.1137 || || || Ortholog(s) have thymidylate kinase activity, uridylate kinase activity, role in dTDP biosynthetic process, dTTP biosynthetic process, dUDP biosynthetic process and cytosol, nucleus localization || 1 -0.28 -0.52 -0.22 0.24 -0.75 -1.82 -0.34 -0.05 -0.14 0.46 -0.53 -0.22 -0.21 0.26 -0.56 -0.41
13937 || orf19.7298 || CHS2 || || Chitin synthase; nonessential; required for wild-type chitin deposition in hyphae; transcript regulated during dimorphic transition; Chs1 and Chs2, but not Chs3, are inhibited by the protoberberine HWY-289; flow model biofilm repressed || 1 -0.31 -0.31 -0.14 0.35 -0.46 -1.41 -0.19 -0.19 0.13 0.64 -0.35 -0.14 -0.40 0.10 -0.31 -0.13
13938 || orf19.3356 || ESP1 || || Putative caspase-like cysteine protease; mutation confers increased sensitivity to nocodazole; periodic mRNA expression, peak at cell-cycle S/G2 phase; mRNA binds She3 || 1 -0.18 -0.09 -0.12 0.01 -0.50 -0.78 -0.40 -0.33 -0.47 -0.13 -0.24 0.25 -0.32 0.35 -1.24 0.24
13939 || orf19.3534 || RHO3 || || Putative Rho family GTPase; possible substrate of protein farnesyltransferase and geranylgeranyltransferase type I; greater transcription in hyphal form than yeast form; plasma membrane-localized || 1 -0.47 -0.50 -0.05 0.05 -1.56 -1.02 -0.61 -0.28 -0.63 0.03 -0.42 -0.12 -0.46 0.15 -1.08 -0.48
13940 || orf19.708 || || || Ortholog(s) have structural constituent of cytoskeleton activity || 1 -0.05 -0.29 -0.33 -0.13 -0.81 -1.15 -0.49 -0.34 -0.82 -0.06 -0.60 -0.32 -0.22 0.15 -1.30 -0.25
13941 || orf19.758 || || || Ortholog(s) have signal sequence binding activity, role in vacuolar transport and late endosome localization || 1 -0.03 -0.06 -0.32 -0.04 -0.91 -0.78 -0.40 -0.23 -0.24 -0.15 -0.42 -0.09 -0.52 0.21 -1.29 -0.21
13942 || orf19.5949 || FAS2 || || Alpha subunit of fatty-acid synthase; required for virulence in mouse systemic infection and rat oropharyngeal infection models; regulated by Efg1; fluconazole-induced; amphotericin B repressed; flow model and Spider biofilm repressed || 1 -0.07 -0.16 -0.26 -0.30 -1.34 -1.44 -0.40 0.01 -0.15 0.13 -0.06 -0.28 -0.48 0.47 -1.47 0.20
13943 || orf19.3356 || ESP1 || || Putative caspase-like cysteine protease; mutation confers increased sensitivity to nocodazole; periodic mRNA expression, peak at cell-cycle S/G2 phase; mRNA binds She3 || 1 0.08 -0.03 -0.15 -0.23 -0.81 -1.19 -0.18 0.05 -0.08 0.15 -0.07 -0.16 -0.27 0.52 -1.38 -0.25
13944 || orf19.5947 || SEC7 || || Putative guanine nucleotide exchange factor (GEF); mutation confers hypersensitivity to Brefeldin A; caspofungin repressed || 1 0.04 0.02 0.14 0.18 -0.59 -0.90 -0.27 0.11 0.07 0.12 -0.08 -0.06 -0.38 0.23 -0.75 -0.24
13945 || orf19.1628 || LAP41 || || Putative aminopeptidase yscI precursor; mutant is viable; protein present in exponential and stationary growth phase yeast cultures; Spider biofilm repressed || 1 -0.04 -0.11 0.29 0.32 -1.49 -0.77 0.04 -0.05 0.23 -0.13 -0.17 -0.04 -0.40 0.41 -0.86 0.19
13946 || orf19.5856 || || || Membrane-localized protein of unknown function || 1 0.02 -0.06 -0.08 -0.11 -1.83 -0.55 -0.05 -0.01 -0.22 0.12 0.03 -0.05 -0.53 0.40 -1.05 -0.15
13947 || orf19.5856 || || || Membrane-localized protein of unknown function || 1 0.02 -0.25 -0.12 -0.21 -1.67 -0.86 0.20 0.03 -0.09 -0.00 -0.25 -0.24 -0.50 0.10 -0.83 -0.27
13948 || orf19.4609 || || || Putative dienelactone hydrolase; protein abundance is affected by URA3 expression in the CAI-4 strain background; protein present in exponential and stationary growth phase yeast cultures; rat catheter biofilm repressed || 1 -0.32 -0.19 -0.09 -0.52 -2.19 -1.05 0.07 -0.11 0.29 0.23 -0.33 -0.31 -0.12 0.46 -1.17 -0.23
13949 || orf19.3911 || SAH1 || || S-adenosyl-L-homocysteine hydrolase; sulfur amino acid metabolism; antigenic in human; alkaline-, fluconazole-induced expression; Gcn4-regulated; amino acid starvation (3-AT) repressed; flow model biofilm induced; Spider biofilm repressed || 1 -0.78 -0.76 -3.40 0.11 0.02 -0.26 -0.57 -0.85 -0.80 -0.16 0.20 -2.27 -0.18
13950 || orf19.5246 || || || Protein of unknown function; Hap43-repressed gene || 1 -0.38 -0.54 -0.08 0.22 -1.74 -1.00 -0.11 -0.13 -0.02 -0.51 -0.46 -0.38 0.03 -0.04 -1.25 -0.13
13951 || orf19.7417 || TSA1 || || TSA/alkyl hydroperoxide peroxidase C (AhPC) family protein; similar to thiol-dependent peroxidases of oxidative stress signaling; antigenic; hyphal surface, nucleus; yeast-form nucleus, cytoplasm; biofilm, phagocytosis, peroxide induced || 1 -0.34 -0.32 0.09 0.30 -1.36 -1.13 -0.03 -0.03 0.19 -0.37 -0.10 -0.53 -0.11 -0.13 -1.62 -0.43
13952 || orf19.3305 || ZCF17 || || Putative Zn(II)2Cys6 transcription factor || 1 0.15 0.14 0.26 0.18 -1.35 -0.79 -0.00 -0.05 0.06 0.25 -0.49 -0.21 0.34 -0.10 -0.63 -0.37
13953 || orf19.4393 || CIT1 || || Citrate synthase; induced by phagocytosis; induced in high iron; Hog1-repressed; Efg1-regulated under yeast, not hyphal growth conditions; present in exponential and stationary phase; Spider biofilm repressed; rat catheter biofilm induced || 1 0.28 0.24 0.41 1.33 -1.92 -2.11 -0.20 -0.35 -0.63 0.34 -0.36 -0.59 -1.18 -0.28 -0.85 -0.98
13954 || orf19.4393 || CIT1 || || Citrate synthase; induced by phagocytosis; induced in high iron; Hog1-repressed; Efg1-regulated under yeast, not hyphal growth conditions; present in exponential and stationary phase; Spider biofilm repressed; rat catheter biofilm induced || 1 0.15 0.17 0.31 1.08 -2.23 -2.46 -0.24 -0.46 -1.02 0.37 -0.46 -0.90 -1.18 -0.34 -1.24 -0.91
13955 || orf19.4959 || || || Protein of unknown function; Spider biofilm repressed || 1 0.15 0.05 -0.23 0.56 -1.61 -1.86 -0.66 -0.33 -0.45 -0.31 -0.31 -0.28 -0.46 -0.33 -1.12 -0.20
13956 || orf19.2451 || PGA45 || || Putative GPI-anchored cell wall protein; repressed in core caspofungin response; Hog1-induced; regulated by Ssn6; Mob2-dependent hyphal regulation; flow model biofilm induced || 1 -0.00 0.18 0.06 0.58 -2.33 -3.49 -0.32 -0.21 -0.37 0.04 -0.09 -1.07 -1.09 -1.03 -2.60 -0.07
13957 || orf19.6988 || OST1 || || Alpha subunit of the oligosaccharyltransferase complex of the ER lumen; catalyzes asparagine-linked glycosylation of newly synthesized proteins; Spider biofilm repressed || 1 0.08 0.00 0.26 0.58 -1.39 -1.38 -0.26 0.06 -0.43 0.06 -0.15 -0.13 -0.76 -0.47 -1.31 -0.14
13958 || orf19.3051 || || || Protein of unknown function; S. pombe ortholog SPAC17A2.02c plays a role in resistance to cadmium; colony morphology-related gene regulation by Ssn6; Spider biofilm repressed || 1 0.05 -0.00 0.44 0.91 -1.74 -1.77 -0.67 -0.03 -0.67 -0.09 0.28 0.14 -1.08 -0.49 -1.48 0.59
13959 || orf19.6988 || OST1 || || Alpha subunit of the oligosaccharyltransferase complex of the ER lumen; catalyzes asparagine-linked glycosylation of newly synthesized proteins; Spider biofilm repressed || 1 -0.03 -0.03 0.09 0.31 -1.10 -1.30 -0.30 0.20 -0.20 0.40 0.12 0.00 -0.49 0.03 -0.97 0.29
13960 || orf19.2937 || PMM1 || || Phosphomannomutase; enzyme of O- and N-linked mannosylation; interconverts mannose-6-phosphate and mannose-l-phosphate; functional homolog of S. cerevisiae Sec53; antigenic in mice; Hap43-induced; flow model and Spider biofilm repressed || 1 0.34 0.33 0.48 0.88 -1.87 -1.55 -0.07 0.36 -0.48 -0.23 0.37 -0.02 -0.47 -0.01 -1.72 0.25
13961 || orf19.1390 || PMI1 || || Phosphomannose isomerase; cell wall biosynthesis enzyme; drug target; functional homolog of S. cerevisiae, E. coli phosphomannose isomerase; Gcn4-regulated; induced on adherence to polystyrene, phagocytosis; 3-AT, Spider biofilm repressed || 1 0.30 0.20 0.21 1.03 -2.04 -2.07 -0.12 0.67 -0.40 0.41 0.41 -0.24 -0.84 -0.28 -1.78 0.14
13962 || orf19.1390 || PMI1 || || Phosphomannose isomerase; cell wall biosynthesis enzyme; drug target; functional homolog of S. cerevisiae, E. coli phosphomannose isomerase; Gcn4-regulated; induced on adherence to polystyrene, phagocytosis; 3-AT, Spider biofilm repressed || 1 0.60 0.49 0.63 1.29 -1.79 -1.91 -0.09 0.75 -0.46 0.37 0.51 -0.25 -0.91 -0.33 -1.72 0.16
13963 || orf19.1761 || || || Predicted olichyl-diphosphooligosaccharide-protein glycotransferase; role in protein N-linked glycosylation; Spider biofilm repressed || 1 0.17 0.21 0.04 0.25 -1.32 -1.07 0.09 0.25 -0.19 0.37 0.04 0.14 -0.14 0.11 -0.53 -0.13
13964 || orf19.5013 || AGM1 || || Phosphoacetylglucosamine mutase (N-acetylglucosamine-phosphate mutase); enzyme of UDP-N-acetylglucosamine (UDP-GlcNAc) biosynthesis || 1 0.15 0.17 0.31 0.96 -2.36 -2.03 0.15 0.43 0.12 0.65 0.22 -0.19 -0.64 0.21 -1.33 -0.02
13965 || orf19.908 || FEN12 || || Putative protein with a predicted role in the elongation of fatty acids; amphotericin B, caspofungin repressed || 1 -0.16 -0.51 -0.02 0.68 -2.79 -1.92 0.52 0.83 0.06 0.61 0.14 -0.33 0.16 0.17 -1.89 -0.53
13966 || orf19.6190 || SRB1 || || Essential GDP-mannose pyrophosphorylase; makes GDP-mannose for protein glycosylation; functional in S. cerevisiae psa1; on yeast-form, not hyphal cell surface; alkaline induced; induced on adherence to polystyrene; Spider biofilm repressed || 1 -0.14 -0.08 0.02 0.28 -2.09 -1.55 0.39 0.32 -0.05 -0.27 0.11 -0.24 -0.10 -0.16 -1.78 -0.01
13967 || orf19.5528 || MOB1 || || Putative mitotic exit network component; periodic mRNA expression, peak at cell-cycle G2/M phase || 1 -0.40 -0.21 0.03 0.62 -2.49 -1.36 -0.08 0.22 -0.36 -0.23 -0.08 -0.44 -0.39 0.07 -1.47 -0.23
13968 || orf19.1680 || TFP1 || || Subunit of vacuolar H+-ATPase; stationary phase enriched protein; sumoylation target; Spider biofilm repressed || 1 -0.00 -0.10 0.20 0.62 -1.16 -1.12 0.19 0.17 -0.16 -0.12 -0.07 -0.20 0.01 0.05 -0.57 -0.10
13969 || orf19.252 || || || Protein of unknown function; S. cerevisiae ortholog Fmp37 which localizes to mitochondria; Hap43-repressed; Spider biofilm repressed || 1 0.05 -0.04 0.10 0.60 -1.51 -1.22 -0.30 0.57 -0.69 0.23 -0.01 -0.16 -0.51 0.17 -0.86 -0.28
13970 || orf19.252 || || || Protein of unknown function; S. cerevisiae ortholog Fmp37 which localizes to mitochondria; Hap43-repressed; Spider biofilm repressed || 1 0.19 0.10 0.53 1.04 -1.33 -0.96 -0.26 0.70 -0.76 0.05 -0.08 -0.13 -0.47 -0.36 -0.82 -0.16
13971 || orf19.1814 || STT4 || || Putative phosphatidylinositol-4-kinase || 1 0.37 0.40 0.45 0.54 -0.62 -1.01 0.15 0.16 0.14 -0.05 -0.26 -0.14 -0.18 0.19 -0.55 -0.32
13972 || orf19.2452 || || || Protein of unknown function; induced in high iron; repressed in core caspofungin response; ketoconazole-repressed; colony morphology-related gene regulation by Ssn6; possibly subject to Kex2 processing || 1 1.58 1.53 0.88 1.82 -2.23 -2.56 0.05 0.28 -0.05 0.72 -0.34 -1.46 -0.16 -0.51 -2.28 -1.49
13973 || orf19.2452 || || || Protein of unknown function; induced in high iron; repressed in core caspofungin response; ketoconazole-repressed; colony morphology-related gene regulation by Ssn6; possibly subject to Kex2 processing || 1 1.69 1.65 0.96 1.92 -2.45 -2.31 0.16 0.31 -0.38 0.66 -0.47 -1.09 -0.16 -0.28 -2.21 -0.99
13974 || orf19.2452 || || || Protein of unknown function; induced in high iron; repressed in core caspofungin response; ketoconazole-repressed; colony morphology-related gene regulation by Ssn6; possibly subject to Kex2 processing || 1 1.79 1.73 1.09 2.17 -2.39 -2.09 0.27 0.54 -0.04 0.88 -0.33 -1.13 -0.01 -0.43 -2.20 -1.28
13975 || orf19.1212 || || || Ortholog(s) have FFAT motif binding, phosphatidylinositol binding activity || 1 1.07 0.90 1.39 1.67 -1.98 -1.87 -0.09 0.21 -0.44 0.09 -0.20 -0.61 -0.17 -0.22 -1.08 -0.78
13976 || orf19.3895 || CHT2 || || GPI-linked chitinase; required for normal filamentous growth; repressed in core caspofungin response; fluconazole, Cyr1, Efg1, pH-regulated; mRNA binds She3 and is localized to yeast-form buds and hyphal tips; Spider biofilm repressed || 1 1.33 1.01 1.17 2.11 -3.79 -4.22 0.68 0.96 -0.66 0.46 -0.65 -1.09 0.88 -0.06 -2.53 -1.20
13977 || orf19.657 || SAM2 || || S-adenosylmethionine synthetase; localizes to surface of hyphae, not yeast cells; alkaline, Hog1-induced; farnesol-downregulated; F-12/CO2 early biofilm induced; Spider biofilm repressed || 1 1.25 1.22 1.31 1.91 -3.78 -3.25 0.45 0.66 -0.23 0.07 -0.81 -1.10 -0.29 0.00 -3.64 -0.38
13978 || orf19.657 || SAM2 || || S-adenosylmethionine synthetase; localizes to surface of hyphae, not yeast cells; alkaline, Hog1-induced; farnesol-downregulated; F-12/CO2 early biofilm induced; Spider biofilm repressed || 1 1.00 0.76 1.10 1.67 -4.39 -3.74 0.05 0.24 -0.43 -0.12 -1.52 -1.51 -0.66 -0.14 -3.97 -0.78
13979 || orf19.2245 || YPT72 || || Vacuolar Rab small monomeric GTPase involved in vacuolar biogenesis; involved in filamentous growth and virulence || 1 0.45 0.40 0.28 0.32 -1.09 -1.11 -0.38 0.14 -0.30 0.10 -0.04 -0.25 -0.09 0.21 -0.75 -0.16
13980 || orf19.556 || || || Protein of unknown function; regulated by Ssn6 || 1 0.38 0.34 0.42 1.23 -2.77 -2.17 0.40 0.97 0.01 0.82 -0.25 -0.43 -0.47 -0.55 -1.43 -0.87
13981 || orf19.556 || || || Protein of unknown function; regulated by Ssn6 || 1 0.55 0.40 -0.01 0.90 -2.73 -2.53 0.15 1.13 0.13 0.69 -0.38 -0.73 -0.58 -0.56 -1.68 -1.28
13982 || orf19.7489 || || || Ortholog(s) have Rho GTPase activator activity || 1 0.29 0.04 0.09 0.46 -0.89 -1.07 0.25 0.42 0.01 0.64 -0.23 -0.54 -0.21 -0.07 -0.76 -0.81
13983 || orf19.3462 || SAR1 || || Functional homolog of S. cerevisiae Sar1; which is required for ER-to-Golgi protein transport; binds GTP; similar to small GTPase superfamily proteins; gene has intron; Hap43-induced; rat catheter biofilm repressed || 1 0.32 0.33 0.22 0.38 -1.50 -1.39 0.51 0.83 0.31 0.67 -0.18 -0.69 0.38 -0.01 -1.14 -0.93
13984 || orf19.3782.2 || || || Ortholog(s) have role in cristae formation and integral to mitochondrial inner membrane, mitochondrial crista junction localization || 1 0.13 0.09 -0.35 -0.24 -1.29 -1.28 0.68 0.83 0.29 0.23 -0.19 -0.52 0.14 0.68 -0.74 -0.73
13985 || orf19.3392 || DOG1 || || Putative 2-deoxyglucose-6-phosphatase; haloacid dehalogenase hydrolase/phosphatase superfamily; similar to S. cerevisiae Dog1, Dog2, Hor1, Rhr2; regulated by Nrg1, Tup1; Spider biofilm repressed || 1 0.22 0.11 -0.21 -0.01 -1.44 -1.37 0.62 0.69 0.58 0.18 -0.67 -0.43 0.22 0.85 -1.30 -0.43
13986 || orf19.3392 || DOG1 || || Putative 2-deoxyglucose-6-phosphatase; haloacid dehalogenase hydrolase/phosphatase superfamily; similar to S. cerevisiae Dog1, Dog2, Hor1, Rhr2; regulated by Nrg1, Tup1; Spider biofilm repressed || 1 -0.15 -0.32 -0.35 0.07 -2.13 -1.74 0.65 0.66 0.42 -0.01 -0.64 -0.66 0.12 0.57 -1.84 -0.59
13987 || orf19.6724 || FUM12 || || Putative fumarate hydratase; enzyme of citric acid cycle; fluconazole, Efg1 repressed; induced in high iron; protein present in exponential and stationary growth phase || 1 0.16 0.02 -0.19 -0.08 -1.42 -1.93 0.30 0.33 -0.05 0.33 -0.93 -1.12 -0.48 1.08 -1.56 -0.82
13988 || orf19.5653 || ATP2 || || F1 beta subunit of F1F0 ATPase complex; antigenic in human, mice; induced by ciclopirox olamine; caspofungin repressed; macrophage/pseudohyphal-induced; detected during exponential and stationary growth phases; Spider biofilm repressed || 1 -0.12 -0.12 -0.13 0.45 -1.64 -1.17 0.37 0.19 0.58 0.31 -0.99 -0.89 0.52 0.40 -1.18 -0.58
13989 || orf19.3066 || ENG1 || || Endo-1,3-beta-glucanase; ortholog of S. cerevisiae Dse4 needed for cell separation; caspofungin, fluconazole repressed; repressed by alpha pheromone in SpiderM medium; flow model biofilm induced; rat catheter biofilm repressed || 1 -0.66 -0.69 -0.16 -0.05 -1.66 -1.56 0.47 0.54 0.01 -0.14 -0.93 -0.98 0.47 1.23 -1.18 -1.05
13990 || orf19.5139 || || || Ortholog of C. dubliniensis CD36 : Cd36_72800, Candida tropicalis MYA-3404 : CTRG_05211 and Candida albicans WO-1 : CAWG_05649 || 1 -0.21 -0.21 0.12 -0.16 -0.90 -1.29 -0.12 -0.06 0.12 0.17 -0.63 -0.93 -0.06 0.09 -1.08 -0.72
13991 || orf19.3765 || RAX2 || || Plasma membrane protein involved in establishment of bud sites and linear direction of hyphal growth; filament induced, repressed by Rim101, Tup1; Hap43-induced; Spider biofilm induced || 1 -0.23 -0.19 -0.28 -0.00 -1.04 -1.43 -0.49 -0.04 0.10 0.21 -0.98 -0.82 -0.60 -0.06 -1.24 -0.97
13992 || orf19.1587 || HGT20 || || Putative glucose transporter of the major facilitator superfamily; the C. albicans glucose transporter family comprises 20 members; 12 probable membrane-spanning segments; regulated by Nrg1 || 1 -0.55 -0.64 -0.27 -0.22 -2.03 -3.13 -0.25 -0.12 0.06 -0.19 -2.03 -1.55 -1.23 -0.18 -2.37 -0.95
13993 || orf19.1587 || HGT20 || || Putative glucose transporter of the major facilitator superfamily; the C. albicans glucose transporter family comprises 20 members; 12 probable membrane-spanning segments; regulated by Nrg1 || 1 -0.55 -0.30 0.21 0.55 -1.64 -2.06 -0.16 -0.04 0.57 0.05 -1.83 -0.99 -0.63 0.52 -2.22 -1.32
13994 || orf19.5169 || || || Ortholog(s) have cytosol, nucleus localization || 1 -0.56 -0.56 0.29 1.22 -2.53 -2.16 -0.21 -0.30 0.02 -0.27 -2.30 -0.94 -0.31 -0.52 -2.75 -1.74
13995 || orf19.6306 || || || Trimethylaminobutyraldehyde dehydrogenase, the third enzyme of the carnitine biosynthesis pathway || 1 0.16 -0.09 0.49 0.65 -1.27 -2.44 -0.27 -0.41 -0.05 -0.29 -1.83 -0.58 -0.81 -0.28 -1.55 -1.13
13996 || orf19.6306 || || || Trimethylaminobutyraldehyde dehydrogenase, the third enzyme of the carnitine biosynthesis pathway || 1 0.17 0.02 0.80 1.10 -2.00 -2.42 -0.71 -0.50 0.20 -0.42 -2.16 -0.62 -0.98 -0.22 -2.34 -1.53
13997 || orf19.5995 || MCA1 || || Putative cysteine protease with similarity to S. cerevisiae Mca1p; has a role in apoptotic cell death upon H2O2 treatment; fungal-specific (no human or murine homolog); farnesol-induced || 1 0.03 -0.00 0.28 0.21 -0.71 -0.66 -0.06 -0.19 -0.10 -0.14 -0.76 -0.33 -0.25 0.07 -0.44 -0.43
13998 || orf19.4885 || MIR1 || || Putative mitochondrial phosphate transporter; caspofungin repressed; expression is increased in a fluconazole-resistant isolate; induced upon adherence to polystyrene || 1 0.03 -0.09 0.03 0.65 -2.04 -1.47 -0.17 -0.14 -0.34 0.23 -1.07 -1.18 -0.48 0.08 -1.00 -1.04
13999 || orf19.4885 || MIR1 || || Putative mitochondrial phosphate transporter; caspofungin repressed; expression is increased in a fluconazole-resistant isolate; induced upon adherence to polystyrene || 1 -0.25 -0.24 -0.10 0.40 -2.28 -1.52 -0.29 0.01 -0.22 0.26 -1.15 -1.00 -0.69 0.05 -1.17 -1.00
14000 || orf19.930 || PET9 || || Mitochondrial ADP/ATP carrier protein involved in ATP biosynthesis; possible lipid raft component; 3 predicted transmembrane helices; flucytosine induced; ketoconazole-induced; downregulated by Efg1p || 1 0.15 0.04 -0.24 0.29 -2.38 -2.23 -0.12 0.16 0.23 0.59 -1.37 -1.53 -0.76 0.11 -1.80 -1.34
14001 || orf19.6254 || ANT1 || || Peroxisomal adenine nucleotide transporter; role in beta-oxidation of medium-chain fatty acid and peroxisome proliferation; rat catheter biofilm induced || 1 0.85 0.83 0.67 0.66 -3.15 -3.95 -0.87 -0.18 -0.54 0.70 -2.68 -1.91 -1.34 -0.44 -4.18 -2.83
14002 || orf19.6254 || ANT1 || || Peroxisomal adenine nucleotide transporter; role in beta-oxidation of medium-chain fatty acid and peroxisome proliferation; rat catheter biofilm induced || 1 0.96 0.80 -0.02 0.49 -4.09 -3.84 -0.57 0.03 -0.56 0.94 -2.43 -1.95 -1.01 -0.63 -3.85 -2.70
14003 || orf19.6254 || ANT1 || || Peroxisomal adenine nucleotide transporter; role in beta-oxidation of medium-chain fatty acid and peroxisome proliferation; rat catheter biofilm induced || 1 1.14 0.98 0.51 1.09 -4.09 -4.07 -0.47 0.19 -0.42 0.94 -2.18 -1.58 -0.99 -0.30 -3.35 -2.29
14004 || orf19.6254 || ANT1 || || Peroxisomal adenine nucleotide transporter; role in beta-oxidation of medium-chain fatty acid and peroxisome proliferation; rat catheter biofilm induced || 1 1.06 0.99 0.63 1.12 -4.25 -4.10 -0.82 -0.33 -0.76 0.53 -2.99 -2.14 -1.23 -0.86 -3.25 -2.49
14005 || orf19.5760 || IHD1 || || GPI-anchored protein; alkaline, hypha-induced; regulated by Nrg1, Rfg1, Tup1 and Tsa1, Tsa1B in minimal media at 37; oralpharyngeal candidasis induced ; Spider biofilm induced; regulated in Spider biofilms by Tec1, Efg1, Ndt80, Rob1, Brg1 || 1 0.58 0.37 1.04 1.32 -4.52 -3.39 -0.43 -0.39 -0.54 0.30 -1.95 -2.95 -0.63 -0.63 -3.77 -2.29
14006 || orf19.5760 || IHD1 || || GPI-anchored protein; alkaline, hypha-induced; regulated by Nrg1, Rfg1, Tup1 and Tsa1, Tsa1B in minimal media at 37; oralpharyngeal candidasis induced ; Spider biofilm induced; regulated in Spider biofilms by Tec1, Efg1, Ndt80, Rob1, Brg1 || 1 0.09 0.27 0.92 1.58 -4.45 -3.11 -1.38 -1.12 -0.69 0.17 -2.91 -2.89 -0.45 -0.90 -4.77 -2.73
14007 || orf19.4805 || || || Putative membrane protein; induced by alpha pheromone in SpiderM medium; Hap4-induced gene; Spider biofilm induced || 1 -0.09 0.15 0.26 0.50 -1.79 -1.58 -0.12 -0.12 -0.25 0.48 -0.63 -0.58 -0.07 0.01 -2.09 -1.35
14008 || orf19.3060 || || || OPutative dolichyl-diphosphooligosaccharide-protein glycotransferase; role in protein N-linked glycosylation; Spider biofilm repressed || 1 -0.05 -0.13 -0.14 0.22 -1.16 -1.62 -0.20 0.09 -0.40 -0.18 -0.38 -0.49 -0.68 -0.51 -0.74 -0.68
14009 || orf19.1801 || CBR1 || || Putative cytochrome B5 reductase; plasma membrane-localized || 1 -0.09 -0.20 -0.62 -0.44 -2.33 -2.19 -0.32 -0.08 -0.87 -0.01 -0.71 -1.02 -0.93 -0.36 -1.46 -1.55
14010 || orf19.556 || || || Protein of unknown function; regulated by Ssn6 || 1 -0.36 -0.38 -1.04 -0.01 -3.28 -2.84 -0.15 0.27 -0.73 0.28 -0.81 -1.16 -1.44 -0.80 -1.78 -1.47
14011 || orf19.556 || || || Protein of unknown function; regulated by Ssn6 || 1 -0.22 -0.38 -0.41 0.54 -3.12 -2.68 -0.24 0.33 -0.49 0.51 -0.82 -1.08 -1.11 -0.85 -1.95 -1.58
14012 || orf19.2298 || WBP1 || || Putative oligosaccharyltransferase subunit; Spider biofilm repressed || 1 -0.30 -0.10 -0.33 0.23 -1.45 -1.75 -0.14 0.39 -0.19 0.42 -0.33 -0.67 -0.42 -0.28 -0.98 -0.70
14013 || orf19.4805 || || || Putative membrane protein; induced by alpha pheromone in SpiderM medium; Hap4-induced gene; Spider biofilm induced || 1 -0.25 -0.30 -0.66 -0.28 -1.69 -1.97 -0.15 -0.04 -0.60 0.16 -0.75 -1.03 -0.06 -0.23 -1.88 -1.40
14014 || orf19.5903 || RAX1 || || Protein with a predicted role in bud site selection; hypha-induced expression; Spider biofilm induced || 1 -0.54 -0.62 -0.13 -0.12 -1.68 -1.49 -0.33 -0.20 0.14 0.35 -0.73 -0.45 -0.07 0.15 -1.00 -0.58
14015 || orf19.5549 || || || Ortholog of C. dubliniensis CD36 : Cd36_63380 and Candida albicans WO-1 : CAWG_05071 || 1 -0.49 -1.05 -0.19 0.20 -2.56 -3.00 -0.46 0.03 -0.38 0.01 -0.83 -0.64 -0.04 0.26 -1.50 -0.98
14016 || orf19.5549 || || || Ortholog of C. dubliniensis CD36 : Cd36_63380 and Candida albicans WO-1 : CAWG_05071 || 1 -0.17 -0.43 0.20 0.33 -2.54 -0.59 0.18 -0.08 0.20 -0.92 -0.91 -0.17 0.57 -1.52 -0.62
14017 || orf19.4765 || PGA6 || || GPI-anchored cell wall adhesin-like protein; induced by high iron; upregulated upon Als2 depletion; mRNA binds She3 and is localized to hyphal tips; Spider biofilm repressed || 1 -0.66 -0.88 -0.59 -0.02 -3.58 -3.27 -0.01 0.29 0.17 0.73 -0.75 -1.61 -0.10 -0.44 -2.00 -1.18
14018 || orf19.2166 || VMA5 || || Putative vacuolar H(+)-ATPase; plasma membrane localized; rat catheter biofilm repressed || 1 -0.01 -0.07 -0.09 0.07 -1.32 -1.33 -0.12 0.23 0.01 0.02 -0.14 -0.62 -0.08 -0.15 -1.06 -0.56
14019 || orf19.2166 || VMA5 || || Putative vacuolar H(+)-ATPase; plasma membrane localized; rat catheter biofilm repressed || 1 -0.14 -0.19 -0.23 -0.08 -1.06 -1.18 -0.23 0.30 0.02 -0.01 -0.25 -0.37 -0.09 -0.04 -0.99 -0.49
14020 || orf19.972 || || || Ortholog(s) have 5'-flap endonuclease activity, role in DNA-dependent DNA replication and Slx1-Slx4 complex localization || 1 -0.50 -0.38 -0.31 -0.15 -2.16 -1.99 -0.05 -0.05 0.21 -0.12 -1.16 -0.89 -0.04 0.39 -1.80 -0.81
14021 || orf19.3378 || || || Protein of unknown function; regulated by Tsa1, Tsa1B in minimal media at 37 degrees C || 1 -0.34 -0.38 0.14 0.39 -4.32 -4.34 0.64 0.47 -0.06 -0.92 -2.22 -2.33 -0.31 0.23 -4.23 -2.95
14022 || orf19.3378 || || || Protein of unknown function; regulated by Tsa1, Tsa1B in minimal media at 37 degrees C || 1 -0.41 -0.69 0.53 0.54 -4.43 -5.14 0.61 0.29 0.09 -0.37 -2.70 -1.95 -0.50 1.26 -3.15 -2.21
14023 || orf19.6570 || NUP || || Nucleoside permease; adenosine and guanosine are substrates, whereas cytidine, adenine, guanine, uridine, uracil are not; similar to a nucleoside permease of S. pombe; possibly processed by Kex2p || 1 -0.29 -0.46 -0.16 0.36 -4.43 -5.10 0.43 0.50 -0.05 0.55 -2.09 -1.93 -1.13 0.13 -2.74 -1.78
14024 || orf19.6570 || NUP || || Nucleoside permease; adenosine and guanosine are substrates, whereas cytidine, adenine, guanine, uridine, uracil are not; similar to a nucleoside permease of S. pombe; possibly processed by Kex2p || 1 0.02 -0.08 -0.07 0.54 -4.61 -5.02 0.64 0.88 0.27 0.68 -2.30 -2.02 -0.71 0.56 -3.98 -1.63
14025 || orf19.5393 || || || Putative cysteine sulfinate decarboxylase; transcript positively regulated by Tbf1; Spider biofilm induced || 1 -0.04 -0.22 0.23 0.62 -2.29 -2.23 0.09 0.11 0.20 0.47 -0.64 -0.75 0.10 0.40 -1.84 -1.05
14026 || orf19.2551 || MET6 || || Essential 5-methyltetrahydropteroyltriglutamate-homocysteine methyltransferase (cobalamin-independent methionine synthase); antigenic in murine/human systemic infection; heat shock, estrogen, GCN-induced; Spider biofilm repressed || 1 0.07 0.09 0.42 0.90 -2.88 -2.84 0.54 0.28 0.02 -0.08 -1.07 -0.98 -0.42 0.15 -1.83 -0.27
14027 || orf19.2551 || MET6 || || Essential 5-methyltetrahydropteroyltriglutamate-homocysteine methyltransferase (cobalamin-independent methionine synthase); antigenic in murine/human systemic infection; heat shock, estrogen, GCN-induced; Spider biofilm repressed || 1 -0.03 0.07 0.27 0.96 -3.13 -2.98 0.33 0.34 -0.07 -0.33 -0.94 -1.03 -0.58 0.06 -2.13 -0.62
14028 || orf19.2551 || MET6 || || Essential 5-methyltetrahydropteroyltriglutamate-homocysteine methyltransferase (cobalamin-independent methionine synthase); antigenic in murine/human systemic infection; heat shock, estrogen, GCN-induced; Spider biofilm repressed || 1 0.07 0.15 -3.16 -2.61 0.34 0.40 -0.02 -1.09 -0.82 -0.39 0.17 -2.24 -0.68
14029 || orf19.6034 || TUB2 || || Beta-tubulin; functional homolog of ScTub2; overproduction makes S. cerevisiae inviable; has two introns; GlcNAc, hypha fluconazole-induced; slow growth, ectopic expression increases white-to opaque switch; rat catheter biofilm repressed || 1 -0.06 -0.16 0.01 0.53 -2.95 -2.72 -0.01 0.40 0.23 0.50 -0.20 -0.62 0.03 -0.08 -1.63 -0.49
14030 || orf19.6034 || TUB2 || || Beta-tubulin; functional homolog of ScTub2; overproduction makes S. cerevisiae inviable; has two introns; GlcNAc, hypha fluconazole-induced; slow growth, ectopic expression increases white-to opaque switch; rat catheter biofilm repressed || 1 -0.08 -0.11 -0.20 0.44 -2.93 -2.58 0.00 0.13 -0.22 0.29 -0.49 -0.74 -0.16 -0.17 -1.95 -0.38
14031 || orf19.3895 || CHT2 || || GPI-linked chitinase; required for normal filamentous growth; repressed in core caspofungin response; fluconazole, Cyr1, Efg1, pH-regulated; mRNA binds She3 and is localized to yeast-form buds and hyphal tips; Spider biofilm repressed || 1 0.35 0.19 0.13 0.85 -4.59 -5.01 -0.05 0.04 -1.10 0.26 -1.33 -1.95 0.33 -0.27 -3.51 -1.18
14032 || orf19.7308 || TUB1 || || Alpha-tubulin; gene has intron; complements cold-sensitivity of S. cerevisiae tub1 mutant; C. albicans has single alpha-tubulin gene, whereas S. cerevisiae has two (TUB1, TUB3); farnesol-upregulated in biofilm; sumoylation target || 1 0.11 -0.09 0.09 0.12 -3.02 -2.85 -0.03 -0.49 -0.45 0.01 -0.86 -0.93 -0.13 -0.32 -1.77 -0.34
14033 || orf19.7308 || TUB1 || || Alpha-tubulin; gene has intron; complements cold-sensitivity of S. cerevisiae tub1 mutant; C. albicans has single alpha-tubulin gene, whereas S. cerevisiae has two (TUB1, TUB3); farnesol-upregulated in biofilm; sumoylation target || 1 0.10 -0.03 0.12 0.40 -2.37 -2.23 -0.23 -0.36 -0.04 0.25 -0.70 -0.60 -0.02 -0.28 -1.22 -0.33
14034 || orf19.4433 || CPH1 || || Transcription factor; for mating, filamentation on solid media, pheromone-stimulated biofilms; in pathway with Ess1, Czf1; required with Efg1 for host cytokine response; regulates galactose metabolism genes; rat cathether biofilm repressed || 1 0.21 0.08 -0.17 -0.05 -1.17 -1.68 0.03 -0.10 -0.10 0.01 -0.83 -0.56 -0.19 -0.16 -1.19 -0.70
14035 || orf19.6570 || NUP || || Nucleoside permease; adenosine and guanosine are substrates, whereas cytidine, adenine, guanine, uridine, uracil are not; similar to a nucleoside permease of S. pombe; possibly processed by Kex2p || 1 0.41 0.24 0.63 0.94 -2.79 -6.19 0.57 0.93 0.51 0.78 -2.06 -2.19 -0.08 0.69 -2.89 -1.46
14036 || orf19.1392 || || || Ortholog(s) have chaperone binding, protein disulfide isomerase activity, unfolded protein binding activity and role in ER-associated ubiquitin-dependent protein catabolic process, protein retention in ER lumen || 1 0.30 0.15 0.19 0.26 -1.65 -1.53 0.40 0.57 0.35 0.19 -0.79 -0.75 0.30 0.16 -0.99 -0.60
14037 || orf19.804 || || || Putative mitochondrial carrier family transporter; rat catheter biofilm induced || 1 0.67 0.36 -0.02 0.15 -2.19 -2.59 0.39 0.76 0.85 0.93 -1.41 -1.17 0.07 0.39 -1.56 -1.61
14038 || orf19.5139 || || || Ortholog of C. dubliniensis CD36 : Cd36_72800, Candida tropicalis MYA-3404 : CTRG_05211 and Candida albicans WO-1 : CAWG_05649 || 1 0.16 0.25 -0.02 0.10 -0.76 -1.12 -0.03 0.22 0.13 0.06 -0.49 -0.47 0.04 0.40 -0.72 -0.61
14039 || orf19.4607 || || || Possible Golgi membrane protein; Hap43-repressed; hypha induced; flow model biofilm induced; Spider biofilm induced || 1 -0.21 -0.28 -0.22 -0.07 -4.24 -5.93 0.23 0.76 1.22 0.62 -2.94 -2.20 0.26 0.64 -2.40 -3.01
14040 || orf19.6821 || || || Ortholog(s) have ubiquitin-protein ligase activity || 1 -0.14 -0.07 -0.28 -0.38 -1.42 -2.13 0.41 0.16 0.15 0.37 -1.31 -0.89 0.13 0.68 -1.10 -0.86
14041 || orf19.1405 || PHO13 || || Putative 4-nitrophenylphosphatase; Hap43p-repressed gene; transcription is regulated upon yeast-hyphal switch || 1 0.47 0.32 0.17 0.13 -3.05 -3.29 0.39 0.62 0.09 0.52 -0.49 -1.50 0.11 0.30 -3.30 -0.71
14042 || orf19.1405 || PHO13 || || Putative 4-nitrophenylphosphatase; Hap43p-repressed gene; transcription is regulated upon yeast-hyphal switch || 1 0.83 0.78 0.25 0.32 -3.51 -3.84 0.71 1.02 0.36 0.69 -0.27 -0.82 0.30 0.75 -3.23 -0.54
14043 || orf19.1702 || ARF3 || || Similar to but not orthologous to S. cerevisae Arf3; transcript filament induced; Tup1 regulated; rat catheter biofilm repressed (see Locus History Note for Assembly 19 correction) || 1 0.08 0.11 -0.05 0.09 -1.57 -2.12 0.16 0.72 0.12 0.56 -0.45 -0.23 -0.15 -0.14 -1.33 -0.09
14044 || orf19.209 || DFG10 || || Ortholog(s) have role in dolichol biosynthetic process, dolichol-linked oligosaccharide biosynthetic process, polyprenol catabolic process, pseudohyphal growth and endoplasmic reticulum localization || 1 0.03 0.10 -0.10 0.26 -0.88 -1.31 0.22 0.43 -0.09 0.05 -0.32 0.01 -0.13 -0.07 -0.88 -0.18
14045 || orf19.7409 || ERV25 || || Component of COPII-coated vesicles; transcript induced upon filamentous growth; rat catheter biofilm repressed || 1 0.25 0.14 -0.09 0.03 -1.27 -1.92 0.15 0.41 -0.29 0.24 -0.08 -0.17 -0.58 -0.16 -1.57 -0.26
14046 || orf19.2250 || SPE3 || || Putative spermidine synthase; predicted role in pantothenate and spermidine biosynthesis; Spider biofilm repressed || 1 0.32 0.30 -0.43 0.11 -1.73 -2.42 0.37 0.71 -0.16 0.14 -0.20 -0.88 -0.58 -0.07 -1.51 -0.85
14047 || orf19.4311 || YNK1 || || Nucleoside diphosphate kinase (NDP kinase); homo-hexameric; soluble protein in hyphae; flucytosine induced; biofilm induced; macrophage-induced protein; stationary phase enriched protein; Spider biofilm repressed || 1 0.30 0.25 -0.53 0.25 -1.93 -2.44 0.10 0.30 -0.43 0.44 -0.52 -1.00 -0.79 -0.18 -1.63 -0.87
14048 || orf19.4311 || YNK1 || || Nucleoside diphosphate kinase (NDP kinase); homo-hexameric; soluble protein in hyphae; flucytosine induced; biofilm induced; macrophage-induced protein; stationary phase enriched protein; Spider biofilm repressed || 1 0.38 0.39 -0.48 0.01 -2.17 -2.37 0.23 0.42 -0.28 0.64 -0.26 -0.78 -0.81 -0.33 -1.63 -0.56
14049 || orf19.4311 || YNK1 || || Nucleoside diphosphate kinase (NDP kinase); homo-hexameric; soluble protein in hyphae; flucytosine induced; biofilm induced; macrophage-induced protein; stationary phase enriched protein; Spider biofilm repressed || 1 0.33 0.34 -0.43 0.17 -2.03 -2.12 0.26 0.39 -0.11 0.59 -0.29 -0.86 -0.70 -0.05 -1.32 -0.53
14050 || orf19.4311 || YNK1 || || Nucleoside diphosphate kinase (NDP kinase); homo-hexameric; soluble protein in hyphae; flucytosine induced; biofilm induced; macrophage-induced protein; stationary phase enriched protein; Spider biofilm repressed || 1 0.32 0.34 -0.47 0.14 -2.28 -2.29 0.31 0.43 -0.26 0.38 -0.28 -0.88 -0.93 0.00 -1.65 -0.39
14051 || orf19.1801 || CBR1 || || Putative cytochrome B5 reductase; plasma membrane-localized || 1 0.34 0.35 0.03 0.05 -1.99 -1.83 -0.01 0.61 -0.04 0.47 -0.31 -0.57 -0.62 -0.04 -1.29 -0.69
14052 || orf19.2250 || SPE3 || || Putative spermidine synthase; predicted role in pantothenate and spermidine biosynthesis; Spider biofilm repressed || 1 0.33 0.34 -0.20 0.30 -2.18 -2.14 0.51 0.89 0.25 0.53 -0.05 -0.51 -0.65 0.32 -1.91 -0.24
14053 || orf19.4311 || YNK1 || || Nucleoside diphosphate kinase (NDP kinase); homo-hexameric; soluble protein in hyphae; flucytosine induced; biofilm induced; macrophage-induced protein; stationary phase enriched protein; Spider biofilm repressed || 1 0.57 0.57 0.06 0.20 -1.70 -2.20 0.66 1.00 0.04 0.94 0.15 -0.59 -0.59 0.17 -1.52 -0.29
14054 || orf19.1996 || CHA1 || || Similar to catabolic ser/thr dehydratases; repressed by Rim101; induced in low iron; regulated on white-opaque switch; filament induced; Tn mutation affects filamentation; flow model biofilm induced; Spider biofilm repressed || 1 1.32 1.25 -0.38 0.15 -4.62 -5.33 -0.51 -0.00 0.60 0.38 -1.13 -0.99 -1.26 0.28 -3.28 -1.99
14055 || orf19.1996 || CHA1 || || Similar to catabolic ser/thr dehydratases; repressed by Rim101; induced in low iron; regulated on white-opaque switch; filament induced; Tn mutation affects filamentation; flow model biofilm induced; Spider biofilm repressed || 1 0.99 1.10 -0.12 0.28 -3.06 -3.55 -0.63 0.01 0.59 0.37 -0.84 -0.02 -1.32 0.21 -2.85 -0.97
14056 || orf19.2685 || PGA54 || || GPI-anchored protein; Hog1-repressed; induced in cyr1 or efg1 mutant or in hyphae; colony morphology-related gene regulation by Ssn6; induced in RHE model; mRNA binds She3; regulated in Spider biofilms by Tec1, Egf1, Ntd80, Rob1, Brg1 || 1 0.19 0.03 -0.01 0.78 -3.11 -3.43 0.68 0.50 0.71 0.80 -0.46 -0.85 0.29 -0.46 -1.36 -0.84
14057 || orf19.2685 || PGA54 || || GPI-anchored protein; Hog1-repressed; induced in cyr1 or efg1 mutant or in hyphae; colony morphology-related gene regulation by Ssn6; induced in RHE model; mRNA binds She3; regulated in Spider biofilms by Tec1, Egf1, Ntd80, Rob1, Brg1 || 1 0.11 0.04 -0.09 0.51 -2.88 -3.35 0.50 0.24 0.56 0.41 -0.48 -0.79 0.21 -0.60 -1.65 -0.64
14058 || orf19.5305 || RHD3 || || GPI-anchored yeast-associated cell wall protein; induced in high iron; clade-associated gene expression; not essential for cell wall integrity; fluconazole-repressed; flow model and Spider biofilm repressed || 1 0.10 -0.03 -3.75 -3.82 0.50 0.35 -0.14 -0.69 -0.56 -0.61 -0.87 -1.14 -0.81
14059 || orf19.5305 || RHD3 || || GPI-anchored yeast-associated cell wall protein; induced in high iron; clade-associated gene expression; not essential for cell wall integrity; fluconazole-repressed; flow model and Spider biofilm repressed || 1 -0.07 -0.10 0.33 0.57 -5.23 -5.31 0.35 0.09 -0.03 -0.46 -0.87 -0.84 -0.59 -1.12 -1.76 -1.09
14060 || orf19.5305 || RHD3 || || GPI-anchored yeast-associated cell wall protein; induced in high iron; clade-associated gene expression; not essential for cell wall integrity; fluconazole-repressed; flow model and Spider biofilm repressed || 1 -0.06 -0.05 0.23 0.71 -5.43 -5.51 0.38 0.31 -0.04 -0.56 -0.73 -0.60 -0.53 -1.40 -1.66 -1.15
14061 || orf19.5305 || RHD3 || || GPI-anchored yeast-associated cell wall protein; induced in high iron; clade-associated gene expression; not essential for cell wall integrity; fluconazole-repressed; flow model and Spider biofilm repressed || 1 -0.02 0.00 0.63 1.02 -5.47 -5.37 0.53 0.34 0.16 -0.45 -0.57 -0.54 -0.44 -1.06 -1.40 -0.82
14062 || orf19.3430 || || || Plasma membrane-associated protein; physically interacts with TAP-tagged Nop1p || 1 0.16 -0.17 0.44 0.45 -1.87 -2.09 -0.34 0.40 -0.87 -0.41 -0.27 -0.35 0.10 -0.63 -1.22 -0.32
14063 || orf19.5137.1 || HHO1 || || Putative histone H1; farnesol regulated; Hap43-induced; contains 5' UTR intron; Spider biofilm repressed || 1 -0.23 -0.35 -0.03 0.46 -1.82 -1.79 -0.46 -0.13 -0.67 -0.58 -0.11 -0.40 0.30 -0.45 -1.09 -0.53
14064 || orf19.9 || || || Ortholog of C. dubliniensis CD36 : Cd36_32700, C. parapsilosis CDC317 : CPAR2_204280, Candida tenuis NRRL Y-1498 : CANTEDRAFT_113831 and Debaryomyces hansenii CBS767 : DEHA2E03916g || 1 -0.04 -0.03 -0.22 -0.05 -1.33 -1.54 -0.06 0.17 -0.01 -0.35 -0.27 -0.41 0.19 -0.22 -0.77 -0.38
14065 || orf19.5092 || || || Ortholog of C. parapsilosis CDC317 : CPAR2_207660.1, C. dubliniensis CD36 : Cd36_07680, Candida tenuis NRRL Y-1498 : CANTEDRAFT_113324 and Debaryomyces hansenii CBS767 : DEHA2C11088g || 1 0.05 -0.31 -0.16 -0.07 -1.05 -1.69 -0.04 0.19 -0.47 -0.26 -0.40 -0.31 0.00 -0.27 -1.27 -0.43
14066 || orf19.433 || || || Ortholog(s) have Rab guanyl-nucleotide exchange factor activity, role in intra-Golgi vesicle-mediated transport, protein complex assembly and TRAPP complex, trans-Golgi network localization || 1 0.05 -0.27 -0.18 -0.08 -0.71 -1.25 0.02 0.00 -0.31 -0.19 -0.13 -0.19 0.03 -0.12 -0.64 -0.50
14067 || orf19.385 || GCV2 || || Glycine decarboxylase P subunit; protein of glycine catabolism; repressed by Efg1; Hog1-induced; induced by Rim101 at acid pH; transcript induced in elevated CO2; stationary phase enriched protein || 1 -0.11 -0.05 -1.37 -0.98 -2.96 -3.15 -0.20 -0.02 -0.24 -0.09 -0.24 -0.11 0.02 0.60 -1.49 -0.86
14068 || orf19.2364 || MIS11 || || Predicted mitochondrial C1-tetrahydrofolate synthase precursor; putative protein of glycine catabolism; repressed by Efg1; fluconazole-induced; stationary phase enriched protein; rat catheter and Spider biofilm repressed || 1 -0.37 -0.15 -0.54 -0.18 -1.39 -2.13 0.37 0.07 0.50 -0.35 -0.61 -0.54 -0.11 0.35 -1.01 -0.32
14069 || orf19.288 || MET13 || || Putative methionine biosynthesis protein; ketoconazole-induced; amphotericin B repressed; Spider biofilm repressed || 1 -0.55 -0.55 -0.92 -0.59 -2.36 -3.09 0.83 0.73 -0.04 -0.52 -0.64 -1.18 -0.30 0.21 -1.33 -0.38
14070 || orf19.288 || MET13 || || Putative methionine biosynthesis protein; ketoconazole-induced; amphotericin B repressed; Spider biofilm repressed || 1 -0.74 -0.75 -1.25 -1.05 -2.56 -3.40 0.75 0.45 -0.18 -0.38 -0.68 -1.28 -0.72 0.29 -1.47 -0.44
14071 || orf19.1850 || SIW14 || || Putative protein phosphatase of the PTP family (tyrosine-specific), similar to S. cerevisiae Siw14p; mutant shows virulence defect; Hap43p-repressed gene || 1 -0.34 -0.45 -0.51 -0.75 -1.35 -1.38 0.14 -0.34 0.06 -0.19 -0.42 -0.66 -0.21 0.10 -0.75 -0.55
14072 || orf19.4609 || || || Putative dienelactone hydrolase; protein abundance is affected by URA3 expression in the CAI-4 strain background; protein present in exponential and stationary growth phase yeast cultures; rat catheter biofilm repressed || 1 -0.31 -0.37 -1.03 -0.21 -2.07 -1.43 0.09 -0.07 -0.07 -0.25 -0.44 -0.46 -0.32 0.00 -1.25 -0.51
14073 || orf19.3751 || || || Putative serine/threonine protein kinase; possibly an essential gene, disruptants not obtained by UAU1 method || 1 -0.12 -0.16 -0.53 -0.09 -2.46 -1.71 0.19 0.12 0.15 0.45 -0.36 -0.24 0.13 -0.03 -0.98 -0.58
14074 || orf19.1426 || || || Ortholog of S. cerevisiae Skg6; localizes to the cell cortex, cell bud neck, cell bud tip, incipient cellular bud site, and is membrane-bound; Spider biofilm induced || 1 -0.55 -0.47 -0.61 -0.39 -2.14 -2.46 -0.05 -0.14 -0.41 0.11 -0.53 -1.06 0.61 -0.30 -0.50 -1.13
14075 || orf19.1426 || || || Ortholog of S. cerevisiae Skg6; localizes to the cell cortex, cell bud neck, cell bud tip, incipient cellular bud site, and is membrane-bound; Spider biofilm induced || 1 -0.48 -0.43 -0.51 -0.20 -1.64 -2.17 0.22 0.09 -0.16 0.37 -0.47 -0.57 0.68 0.19 -0.35 -0.99
14076 || orf19.1232 || VRG4 || || GDP-mannose transporter; essential; required for glycosylation, hyphal growth; functional homolog of S. cerevisiae Vrg4p, which imports GDP-mannose from cytoplasm to Golgi for protein and lipid mannosylation; no mammalian homolog || 1 -0.23 -0.23 -0.44 0.20 -1.95 -2.14 0.22 0.57 -0.16 0.44 -0.29 -0.48 0.08 0.18 -1.04 -1.14
14077 || orf19.4255 || ECM331 || || GPI-anchored protein; mainly at plasma membrane, also at cell wall; Hap43, caspofungin-induced; Plc1-regulated; Hog1, Rim101-repressed; colony morphology-related regulated by Ssn6; induced by ketoconazole and hypoxia || 1 -1.20 -1.26 -1.41 -0.60 -4.71 -4.13 0.28 0.34 -0.06 0.30 -1.93 -1.68 -0.71 -0.21 -2.00 -2.74
14078 || orf19.4255 || ECM331 || || GPI-anchored protein; mainly at plasma membrane, also at cell wall; Hap43, caspofungin-induced; Plc1-regulated; Hog1, Rim101-repressed; colony morphology-related regulated by Ssn6; induced by ketoconazole and hypoxia || 1 -0.82 -0.95 -0.88 -0.18 -3.56 -3.72 0.46 0.46 0.14 0.58 -1.63 -1.41 -0.69 0.36 -1.54 -2.33
14079 || orf19.4255 || ECM331 || || GPI-anchored protein; mainly at plasma membrane, also at cell wall; Hap43, caspofungin-induced; Plc1-regulated; Hog1, Rim101-repressed; colony morphology-related regulated by Ssn6; induced by ketoconazole and hypoxia || 1 -0.81 -0.90 -1.14 -0.67 -4.08 -3.94 0.51 0.43 0.02 0.51 -1.86 -1.39 -0.54 0.06 -1.52 -2.05
14080 || orf19.4255 || ECM331 || || GPI-anchored protein; mainly at plasma membrane, also at cell wall; Hap43, caspofungin-induced; Plc1-regulated; Hog1, Rim101-repressed; colony morphology-related regulated by Ssn6; induced by ketoconazole and hypoxia || 1 -1.00 -1.03 -1.05 -0.56 -4.63 -3.87 0.66 0.52 0.16 0.74 -1.78 -1.17 -0.49 0.28 -1.43 -2.35
14081 || orf19.2843 || RHO1 || || Small GTPase of Rho family; regulates beta-1,3-glucan synthesis activity and binds Gsc1p; essential; expected to be geranylgeranylated by geranylgeranyltransferase type I; plasma membrane-localized || 1 -0.25 -0.38 -0.55 -0.19 -1.64 -1.55 0.06 0.10 -0.00 0.28 -0.37 -0.44 0.12 0.02 -0.50 -0.67
14082 || orf19.1232 || VRG4 || || GDP-mannose transporter; essential; required for glycosylation, hyphal growth; functional homolog of S. cerevisiae Vrg4p, which imports GDP-mannose from cytoplasm to Golgi for protein and lipid mannosylation; no mammalian homolog || 1 -0.74 -0.75 -1.06 -0.48 -2.19 -1.97 -0.05 0.25 -0.13 0.58 -0.43 -0.43 -0.30 0.61 -0.91 -1.01
14083 || orf19.3732 || ERG25 || || Putative C-4 methyl sterol oxidase; C4-demethylation of ergosterol biosynthesis intermediates, based on similarity to S. cerevisiae Erg25; fluconazole-induced; induced in azole-resistant strain; rat catheter and Spider biofilm induced || 1 -0.51 -0.63 -0.82 -0.23 -1.63 -1.75 0.08 0.06 -0.20 0.77 -0.87 -0.50 0.27 0.43 -0.61 -1.19
14084 || orf19.1376 || || || Ortholog(s) have SNAP receptor activity, phosphatidic acid binding activity || 1 -0.21 -0.31 -0.36 -0.29 -0.98 -1.25 -0.12 0.00 -0.25 0.41 -0.60 -0.49 -0.25 0.23 -0.67 -0.62
14085 || orf19.5658 || MNN10 || || Ortholog(s) have alpha-1,6-mannosyltransferase activity, role in ascospore formation, barrier septum assembly and alpha-1,6-mannosyltransferase complex localization || 1 -0.26 -0.37 -0.24 -0.12 -0.64 -1.07 -0.13 0.16 -0.09 0.36 -0.20 -0.14 -0.22 0.07 -0.38 -0.49
14086 || orf19.6155 || || || Ortholog(s) have DNA ligase (ATP) activity and role in DNA ligation, DNA recombination, DNA replication, Okazaki fragment processing, base-excision repair, mitotic cell cycle, nucleotide-excision repair, telomere maintenance || 1 -0.26 -0.26 -0.37 -0.46 -0.63 -1.78 0.02 0.20 -0.29 0.43 0.08 -0.46 -0.77 -0.21 -0.87 0.14
14087 || orf19.5367 || RDH54 || || Putative DNA-dependent ATPase with a predicted role in DNA recombination and repair; transcriptionally induced by interaction with macrophages || 1 -0.37 -0.39 -0.84 -0.34 -1.25 -1.58 -0.51 -0.05 -0.34 0.46 -0.03 -0.56 -0.95 0.41 -0.78 0.38
14088 || orf19.4230 || || || 20S proteasome subunit (beta7); protein present in exponential and stationary growth phase yeast cultures || 1 -0.01 -0.22 -0.17 -0.22 -0.58 -0.93 -0.10 0.04 -0.14 0.08 -0.16 -0.20 -0.33 0.15 0.01 0.07
14089 || orf19.1949 || VPS1 || || Dynamin-family GTPase-related protein; induced upon adherence to polystyrene; regulated by Gcn2p and Gcn4p || 1 0.07 -0.10 -0.26 -0.14 -0.74 -0.85 0.10 -0.02 -0.41 0.16 -0.13 -0.25 -0.22 0.05 -0.22 0.05
14090 || orf19.1221 || ALG2 || || Putative mannosyltransferase involved in cell wall mannan biosynthesis; transcription is elevated in chk1, nik1, and sln1 homozygous null mutants || 1 0.07 -0.05 -0.35 -0.07 -1.03 -0.91 -0.14 -0.04 -0.17 0.30 -0.49 -0.17 -0.49 -0.13 -0.34 -0.06
14091 || orf19.4433 || CPH1 || || Transcription factor; for mating, filamentation on solid media, pheromone-stimulated biofilms; in pathway with Ess1, Czf1; required with Efg1 for host cytokine response; regulates galactose metabolism genes; rat cathether biofilm repressed || 1 0.12 -0.26 -0.38 -0.22 -1.58 -2.49 0.20 -0.57 -0.15 0.07 -0.82 -0.43 -0.75 0.09 -1.28 -0.04
14092 || orf19.1857 || || || Putative L-azetidine-2-carboxylic acid acetyltransferase; mutants are viable || 1 -0.53 -0.38 -0.07 -0.01 -1.52 -1.42 0.41 0.74 0.56 -0.21 -0.22 -0.19 -0.50 0.11 -0.80 0.10
14093 || orf19.2364 || MIS11 || || Predicted mitochondrial C1-tetrahydrofolate synthase precursor; putative protein of glycine catabolism; repressed by Efg1; fluconazole-induced; stationary phase enriched protein; rat catheter and Spider biofilm repressed || 1 -0.46 -0.60 -0.45 -0.17 -3.05 -2.75 0.54 0.31 0.40 -0.41 -0.46 -0.31 -0.49 0.11 -1.87 -0.05
14094 || orf19.1570 || ERG7 || || 2,3-epoxysqualene-lanosterol cyclase (lanosterol synthase), conversion of 2,3-oxidosqualene to lanosterol in sterol biosynthesis; fluconazole-induced; possibly essential, disruptants not obtained by UAU1 method; rat catheter biofilm induced || 1 -0.39 -0.65 -0.43 -0.41 -1.48 -1.24 0.26 -0.07 0.28 -0.01 -0.00 -0.10 -0.44 0.08 -1.02 0.28
14095 || orf19.3591 || APE3 || || Putative vacuolar aminopeptidase Y,; regulated by Gcn2 and Gcn4; rat catheter and Spider biofilm repressed || 1 -0.74 -0.84 -0.73 -0.34 -1.57 -1.52 0.87 0.34 0.33 -0.37 0.13 0.07 -0.00 0.40 -0.47 0.31
14096 || orf19.3591 || APE3 || || Putative vacuolar aminopeptidase Y,; regulated by Gcn2 and Gcn4; rat catheter and Spider biofilm repressed || 1 -0.57 -0.57 -0.46 -0.19 -1.62 -1.68 0.80 0.29 0.56 -0.19 0.02 0.11 0.03 0.36 -0.68 -0.22
14097 || orf19.4966 || AGC1 || || Putative mitochondrial carrier protein; transcript is alkaline upregulated rat catheter biofilm induced || 1 -0.79 -0.89 -1.25 -0.46 -2.71 -2.21 0.72 -0.01 0.14 -0.01 -0.06 0.01 0.33 0.54 -0.66 -0.16
14098 || orf19.4966 || AGC1 || || Putative mitochondrial carrier protein; transcript is alkaline upregulated rat catheter biofilm induced || 1 -0.44 -0.37 -0.78 -0.08 -2.33 -1.82 0.46 0.24 0.32 0.23 0.08 0.26 0.44 0.61 -0.44 0.41
14099 || orf19.1725 || || || Putative adhesin-like protein || 1 -0.74 -0.86 -0.51 -0.48 -2.50 -2.16 0.47 0.73 0.30 -0.12 0.66 0.07 0.94 0.21 -0.66 0.12
14100 || orf19.6163 || CSE4 || || Centromeric histone H3 variant; role in structural changes of centromeric nucleosomes during cell cycle; 4 nucleosomes bind 1 centromere, each has 1 Cse4 molecule during most of cell cycle, 2 molecules in anaphase; Spider biofilm repressed || 1 -0.70 -0.33 -0.48 -0.17 -1.84 -1.75 0.42 0.68 0.14 0.54 0.82 -0.14 0.34 0.31 -0.77 -0.06
14101 || orf19.1327 || RBT1 || || Cell wall protein with similarity to Hwp1; required for virulence; predicted glycosylation; fluconazole, Tup1 repressed; farnesol, alpha factor, serum, hyphal and alkaline induced; Rfg1, Rim101-regulated || 1 -0.52 -0.58 -0.33 -0.27 -1.98 -1.77 -0.01 0.51 0.37 -0.28 0.05 -0.43 0.88 0.23 -0.95 -0.36
14102 || orf19.1725 || || || Putative adhesin-like protein || 1 -0.86 -1.06 -0.80 -0.99 -3.16 -2.86 -0.32 0.31 -0.06 -0.39 0.09 -0.65 0.63 -0.04 -1.43 -0.09
14103 || orf19.5246 || || || Protein of unknown function; Hap43-repressed gene || 1 -0.52 -0.55 -0.25 -0.23 -1.56 -1.62 0.12 0.13 0.04 -0.42 -0.43 -0.36 0.26 0.44 -0.88 0.12
14104 || orf19.4192 || CDC14 || || Protein involved in exit from mitosis and morphogenesis; ortholog of S. cerevisiae Cdc14p, which is a dual-specificity phosphatase and cell-cycle regulator; suppresses S. cerevisiae cdc15-lyt1, dbf2-2, and (partially) tem1 mutant phenotypes || 1 -0.65 -0.76 -1.05 -0.74 -2.12 -2.50 -0.15 0.19 -0.79 -0.14 0.44 -0.06 0.14 0.26 -1.61 0.27
14105 || orf19.4192 || CDC14 || || Protein involved in exit from mitosis and morphogenesis; ortholog of S. cerevisiae Cdc14p, which is a dual-specificity phosphatase and cell-cycle regulator; suppresses S. cerevisiae cdc15-lyt1, dbf2-2, and (partially) tem1 mutant phenotypes || 1 -0.45 -0.40 -0.97 -0.57 -2.14 -2.11 0.23 0.13 -0.83 -0.17 0.51 -0.14 0.45 0.02 -1.50 0.30
14106 || orf19.6119 || || || Protein of unknown function; Spider biofilm repressed || 1 -0.31 -0.30 -0.39 -0.19 -1.10 -1.20 -0.02 0.01 -0.22 -0.32 0.28 0.16 0.17 -0.05 -0.63 0.37
14107 || orf19.6124 || ACE2 || || Transcription factor; similar to S. cerevisiae Ace2 and Swi5; regulates morphogenesis, cell separation, adherence, virulence in a mice; mutant is hyperfilamentous; rat catheter and Spider biofilm induced || 1 -0.45 -0.61 -0.50 -0.28 -1.52 -1.50 -0.20 -0.05 -0.39 -0.46 0.00 -0.06 -0.22 0.08 -0.90 0.42
14108 || orf19.1185 || || || Ortholog(s) have protein homodimerization activity, ubiquitin-protein ligase activity || 1 -0.26 -0.46 -0.02 -0.19 -1.06 -1.06 -0.11 0.13 -0.32 -0.10 0.19 -0.05 0.02 0.37 -0.62 0.26
14109 || orf19.327 || HTA3 || || Putative histone H2A; amphotericin B repressed; flucytosine induced; RNA abundance regulated by tyrosol and cell density; Spider biofilm repressed || 1 -0.65 -0.67 -0.35 -0.10 -2.22 -1.77 -0.05 0.32 -0.15 -0.22 0.71 0.63 0.33 0.37 -0.89 0.16
14110 || orf19.327 || HTA3 || || Putative histone H2A; amphotericin B repressed; flucytosine induced; RNA abundance regulated by tyrosol and cell density; Spider biofilm repressed || 1 -0.97 -1.18 -0.67 -0.56 -2.82 -2.15 -0.09 0.21 -0.47 -0.37 0.59 0.37 0.10 0.05 -1.16 -0.24
14111 || orf19.6010 || CDC5 || || Polo-like kinase; member of conserved Mcm1 regulon; depletion causes defects in spindle elongation and Cdc35-dependent filamentation; virulence-group-correlated expression; likely essential (UAU1 method); Spider biofilm repressed || 1 -0.72 -0.83 -0.69 -0.45 -2.99 -1.57 -0.04 0.08 -0.34 -0.21 0.26 0.05 0.01 -0.17 -0.76 -0.04
14112 || orf19.1393 || || || Ortholog(s) have NAD transporter activity, pyruvate secondary active transmembrane transporter activity, role in NAD transmembrane transport, mitochondrial pyruvate transport and endoplasmic reticulum, mitochondrion localization || 1 -0.94 -0.93 -0.63 -0.56 -1.42 -0.95 -0.22 -0.03 -0.39 -0.23 0.17 0.00 0.22 0.28 -0.56 -0.04
14113 || orf19.1725 || || || Putative adhesin-like protein || 1 -1.46 -1.45 -0.98 -0.69 -2.13 -2.47 -0.28 -0.03 0.02 -0.47 -0.21 0.13 0.20 0.17 -1.31 -0.03
14114 || orf19.4959 || || || Protein of unknown function; Spider biofilm repressed || 1 -0.46 -0.53 -0.72 -0.68 -1.59 -1.48 -0.22 -0.02 -0.62 -0.63 0.10 -0.26 0.45 -0.22 -0.61 0.31
14115 || orf19.5964 || ARF2 || || Putative ADP-ribosylation factor; mutation confers hypersensitivity to Brefeldin A; Spider biofilm repressed || 1 -0.36 -0.42 -0.65 -0.68 -1.46 -1.57 -0.08 0.01 -0.22 0.05 0.14 0.06 -0.14 0.03 -0.15 0.12
14116 || orf19.3086 || SEC10 || || Ortholog(s) have role in Golgi to plasma membrane transport, cytokinetic cell separation, exocytosis and cell cortex of cell tip, cell division site, cytosol, exocyst, mating projection tip, mitotic spindle pole body, nucleus localization || 1 -0.28 -0.39 -0.50 -0.49 -0.90 -1.09 -0.18 0.00 -0.23 -0.24 0.08 -0.10 -0.24 0.17 -0.24 -0.02
14117 || orf19.6553 || || || Membrane-localized protein of unknown function; possibly secreted; fluconazole-induced || 1 -0.32 -0.49 -0.50 -0.37 -1.40 -1.38 -0.01 0.22 -0.33 -0.39 0.34 -0.10 -0.43 -0.14 -0.10 -0.17
14118 || orf19.6929 || || || Ortholog(s) have acid phosphatase activity and cytosol, nucleus localization || 1 0.09 -0.17 -0.98 -0.42 -1.01 -1.45 0.30 0.39 -0.41 0.21 0.17 -0.23 -0.26 -0.45 -0.66 0.14
14119 || orf19.2864.1 || RPL28 || || Putative ribosomal protein; Plc1-regulated; downregulated upon phagocytosis by murine macrophage; Spider biofilm repressed || 1 0.06 -0.25 -1.71 -1.07 -3.04 -3.41 0.34 0.63 -0.09 0.30 0.50 -0.28 -0.27 -0.51 -0.84 -0.19
14120 || orf19.3207 || CCN1 || || G1 cyclin; required for hyphal growth maintenance (not initiation); cell-cycle regulated transcription (G1/S); Cdc28p-Ccn1p initiates Cdc11p S394 phosphorylation on hyphal induction; expression in S. cerevisiae inhibits pheromone response || 1 0.15 -0.18 -0.44 -0.53 -1.71 -2.37 0.12 0.30 -0.54 -0.01 0.39 -0.06 0.19 -0.56 -0.17 -0.18
14121 || orf19.2070 || || || Ortholog(s) have role in G1/S transition of mitotic cell cycle, chromatin remodeling, nucleosome disassembly, transcription elongation from RNA polymerase II promoter and RSC complex localization || 1 -0.35 -0.17 -0.43 -0.40 -1.27 -1.45 0.05 0.33 -0.38 0.14 0.46 -0.08 0.38 -0.17 -0.16 0.16
14122 || orf19.1893 || || || Protein of unknown function; Spider biofilm repressed || 1 0.21 -0.20 -0.87 -0.07 -1.61 -1.88 0.30 0.22 0.15 0.36 0.23 -0.16 0.28 0.04 -0.46 0.28
14123 || orf19.3207 || CCN1 || || G1 cyclin; required for hyphal growth maintenance (not initiation); cell-cycle regulated transcription (G1/S); Cdc28p-Ccn1p initiates Cdc11p S394 phosphorylation on hyphal induction; expression in S. cerevisiae inhibits pheromone response || 1 0.22 0.05 -0.34 -0.42 -2.95 -2.68 0.51 0.65 -0.08 0.55 0.26 0.34 0.42 0.04 -0.53 -0.22
14124 || orf19.3207 || CCN1 || || G1 cyclin; required for hyphal growth maintenance (not initiation); cell-cycle regulated transcription (G1/S); Cdc28p-Ccn1p initiates Cdc11p S394 phosphorylation on hyphal induction; expression in S. cerevisiae inhibits pheromone response || 1 -0.15 -0.08 -0.28 -0.33 -2.65 -2.73 0.20 0.14 -0.14 0.36 0.19 0.35 0.25 -0.12 -0.90 -0.36
14125 || orf19.6737 || || || Protein of unknown function; mutants are viable; induced in a cyr1, ras1, or efg1 homozygous null || 1 -0.06 -0.02 -0.03 -0.28 -2.34 -2.51 0.30 0.57 -0.02 0.52 0.26 0.36 0.03 0.19 -1.23 -0.48
14126 || orf19.6007 || || || Predicted fatty acid acyl transferase-related protein domain; repressed by prostaglandins || 1 -0.11 -0.35 -0.51 -0.42 -2.16 -1.24 0.26 0.93 -0.07 0.40 0.62 -0.03 -0.14 0.12 -0.39 -0.25
14127 || orf19.5964 || ARF2 || || Putative ADP-ribosylation factor; mutation confers hypersensitivity to Brefeldin A; Spider biofilm repressed || 1 -0.08 -0.37 -0.28 -0.12 -1.71 -1.48 0.41 0.70 0.02 0.22 0.63 0.38 0.40 0.05 0.00 -0.00
14128 || orf19.3856 || CDC28 || || Cyclin-dependent protein kinase; interacts with regulatory subunit Cyb1; determination of cell morphology during the cell cycle; phosphorylated mostly by Swe1 and phosphorylation is regulated by Hsl1; 5'-UTR intron; Spider biofilm repressed || 1 -0.36 -0.45 -0.55 0.05 -1.51 -1.86 -0.20 0.39 -0.80 -0.06 1.00 0.46 -0.28 0.17 -0.53 0.18
14129 || orf19.3856 || CDC28 || || Cyclin-dependent protein kinase; interacts with regulatory subunit Cyb1; determination of cell morphology during the cell cycle; phosphorylated mostly by Swe1 and phosphorylation is regulated by Hsl1; 5'-UTR intron; Spider biofilm repressed || 1 -0.65 -0.72 -1.34 -0.43 -2.32 -2.12 -0.29 0.36 -0.83 -0.03 0.93 0.11 -0.49 0.21 -0.74 0.00
14130 || orf19.1238 || TUB4 || || Putative gamma-tubulin; induced upon adherence to polystyrene; transcript regulated by Nrg1 and Mig1; periodic mRNA expression, peak at cell-cycle S/G2 phase || 1 -0.44 -0.76 -0.77 -0.20 -1.55 -1.93 -0.41 0.18 -0.79 -0.01 0.68 -0.18 0.15 -0.46 -1.02 -0.16
14131 || orf19.1702 || ARF3 || || Similar to but not orthologous to S. cerevisae Arf3; transcript filament induced; Tup1 regulated; rat catheter biofilm repressed (see Locus History Note for Assembly 19 correction) || 1 -0.03 -0.02 -0.49 -0.19 -1.04 -1.76 0.02 0.59 -0.12 0.56 -0.07 -0.31 0.06 -0.37 -0.77 -0.53
14132 || orf19.3013 || CDC12 || || Septin; essential for viability; forms ring at sites of cell division and also forms filaments in mature chlamydospore; filamentous growth induced; regulated by Nrg1, Tup1, tyrosol and cell density; rat catheter biofilm repressed || 1 0.04 0.06 -0.09 -0.02 -0.78 -1.37 0.01 0.23 0.02 0.53 0.08 -0.31 -0.07 -0.10 -1.00 -0.55
14133 || orf19.2347 || MNN2 || || Alpha-1,2-mannosyltransferase; similar to S. cerevisiae Mnn2; role in cell wall integrity, temperature sensitivity; iron utilization in low iron; Tn mutation affects filamentous growth; filament induced; increased chitin exposes beta-glucan || 1 -0.15 -0.24 -0.43 -0.31 -1.16 -1.48 0.01 0.47 0.19 0.66 0.24 -0.14 -0.39 -0.06 -1.00 -0.30
14134 || orf19.5182 || POL3 || || Large subunit of DNA polymerase III; partially complements defects of an S. cerevisiae cdc2 mutant; differing reports about periodic (G1/S) or non-periodic mRNA expression through cell cycle; Hap43p-repressed || 1 0.28 0.03 -0.20 -0.28 -0.78 -1.21 -0.11 0.23 -0.10 0.39 -0.04 -0.31 -0.30 0.21 -0.84 -0.31
14135 || orf19.6562 || RNH35 || || Putative ribonuclease H2 catalytic subunit; flucytosine induced; Spider biofilm repressed || 1 -0.05 -0.02 -0.55 -0.59 -1.01 -2.38 0.18 1.03 -0.06 0.50 0.71 -0.09 0.05 0.97 -1.50 0.12
14136 || orf19.7394 || GDA1 || || Golgi membrane GDPase, required for wild-type O-mannosylation, not N-glycosylation; required for wild-type hyphal induction, cell wall, and cell surface charge; not required for HeLa cell adherence; functional homolog of S. cerevisiae Gda1p || 1 -0.30 -0.29 -0.47 0.22 -2.15 -2.18 0.05 0.70 -0.22 0.77 0.53 0.17 -0.06 0.46 -1.11 -0.22
14137 || orf19.6293 || EMP24 || || COPII-coated vesicle component || 1 -0.28 -0.34 -0.18 0.01 -1.32 -1.62 0.18 0.79 -0.32 0.45 0.46 0.01 -0.27 0.12 -0.75 -0.28
14138 || orf19.3322 || DUT1 || || dUTP pyrophosphatase; cell-cycle regulated if expressed in S. cerevisiae; upstream MluI and SCB elements; 17-beta-estradiol, ethynyl estradiol, macrophage induced; decreased in stationary phase yeast; rat catheter, Spider biofilm repressed || 1 -0.54 -0.50 0.01 -0.15 -1.05 -2.25 0.01 0.69 0.02 0.62 0.34 0.14 -0.36 0.27 -1.29 0.14
14139 || orf19.1137 || || || Ortholog(s) have thymidylate kinase activity, uridylate kinase activity, role in dTDP biosynthetic process, dTTP biosynthetic process, dUDP biosynthetic process and cytosol, nucleus localization || 1 -0.20 -0.70 -0.68 -0.23 -1.36 -3.22 0.24 0.87 -0.03 0.56 0.61 -0.22 -0.47 0.28 -1.08 0.04
14140 || orf19.3322 || DUT1 || || dUTP pyrophosphatase; cell-cycle regulated if expressed in S. cerevisiae; upstream MluI and SCB elements; 17-beta-estradiol, ethynyl estradiol, macrophage induced; decreased in stationary phase yeast; rat catheter, Spider biofilm repressed || 1 -0.87 -0.31 -0.78 -0.47 -1.97 -3.23 0.75 1.47 -0.24 0.59 1.10 0.04 -0.46 0.11 -1.50 -0.17
14141 || orf19.1115 || GUK1 || || Putative guanylate kinase; identified in extracts from biofilm and planktonic cells; protein level decrease in stationary phase cultures; Hap43p-induced gene || 1 -0.36 -0.45 -0.71 -0.26 -1.58 -2.55 0.45 1.34 -0.22 1.07 1.29 0.09 -0.01 0.23 -1.71 0.14
14142 || orf19.1115 || GUK1 || || Putative guanylate kinase; identified in extracts from biofilm and planktonic cells; protein level decrease in stationary phase cultures; Hap43p-induced gene || 1 -0.23 -0.16 -0.54 -0.24 -1.10 -2.38 0.32 1.08 -0.37 0.88 1.14 0.09 0.22 0.44 -1.48 0.18
14143 || orf19.548 || CDC10 || || Septin, required for wild-type cell, hyphal, or chlamydospore morphology; role in virulence and kidney tissue invasion in mouse infection; forms ring at sites of cell division and filaments in mature chlamydospore; Spider biofilm repressed || 1 0.21 0.18 -0.49 -0.27 -1.73 -2.40 0.51 0.92 -0.36 0.52 0.75 -0.50 -0.04 0.12 -1.22 0.12
14144 || orf19.6293 || EMP24 || || COPII-coated vesicle component || 1 -0.37 -0.48 -0.15 -0.16 -1.45 -1.93 0.08 0.84 -0.35 0.35 0.62 -0.40 -0.17 -0.46 -0.95 -0.08
14145 || orf19.6610 || || || Ortholog(s) have microtubule plus-end binding, structural constituent of cytoskeleton activity || 1 -0.21 -0.34 -0.72 0.23 -1.01 -1.53 0.04 0.48 -0.25 0.71 0.09 -0.04 -0.07 0.24 -0.69 -0.12
14146 || orf19.6078.1 || RFC52 || || Putative replication factor C complex protein; periodic mRNA expression, peak at cell-cycle G1/S phase; overlaps orf19.6079 || 1 -0.41 -0.44 -0.26 0.30 -1.15 -2.03 -0.38 0.75 -0.56 0.72 0.90 0.15 -0.67 0.02 -1.16 0.23
14147 || orf19.3549 || CDC21 || || Putative thymidylate synthase; flucytosine induced; rat catheter biofilm repressed; Spider biofilm repressed || 1 0.09 -0.06 0.06 0.13 -1.01 -1.63 -0.15 0.57 -0.51 0.41 0.68 -0.08 -0.69 0.35 -0.96 0.18
14148 || orf19.6812 || PMT2 || || Protein mannosyltransferase (PMT) with roles in hyphal growth and drug sensitivity; member of the PMT family which includes Pmt1p, Pmt2p, Pmt4p, Pmt5p, and Pmt6p; induced during cell wall regeneration; essential || 1 -0.08 -0.12 0.01 0.19 -1.28 -1.36 0.15 0.39 -0.45 0.22 0.39 -0.04 -0.01 -0.05 -0.69 0.31
14149 || orf19.3561 || CDC7 || || Putative kinase; cell-cycle regulated periodic mRNA expression; S. cerevisiae ortholog is not cell-cycle regulated; possibly an essential gene, disruptants not obtained by UAU1 method || 1 -0.00 -0.23 -0.16 0.05 -0.94 -1.70 0.08 0.28 -0.43 0.09 0.17 -0.15 0.04 0.48 -0.93 0.29
14150 || orf19.3752 || RAD51 || || Protein involved in homologous recombination and DNA repair; flucytosine induced; slow growth and increased white-to-opaque switching frequency in null mutant || 1 -0.27 -0.01 -0.01 -0.07 -1.51 -1.90 0.05 0.35 -0.14 0.12 0.17 -0.01 -0.03 0.70 -1.08 0.35
14151 || orf19.3462 || SAR1 || || Functional homolog of S. cerevisiae Sar1; which is required for ER-to-Golgi protein transport; binds GTP; similar to small GTPase superfamily proteins; gene has intron; Hap43-induced; rat catheter biofilm repressed || 1 -0.19 -0.22 -0.05 -0.33 -0.93 -1.11 -0.04 0.19 -0.16 0.22 0.31 0.27 -0.14 0.12 -0.58 0.31
14152 || orf19.3965 || || || Ortholog(s) have role in double-strand break repair via homologous recombination, meiotic gene conversion, reciprocal meiotic recombination, replication fork protection and Smc5-Smc6 complex, cytosol, nucleus localization || 1 -0.58 -0.62 -0.25 -0.24 -1.26 -2.07 -0.17 -0.03 0.01 0.66 0.25 -0.09 -0.47 0.15 -1.27 0.47
14153 || orf19.4853 || HCM1 || || Protein with forkhead domain; similar to S. cerevisiae Hcm1p; Hap43p-induced gene || 1 -0.83 -0.77 -0.30 -0.05 -2.24 -2.30 -0.57 -0.23 -0.44 0.83 -0.32 0.14 -0.12 -0.61 -2.26 -1.32
14154 || orf19.4853 || HCM1 || || Protein with forkhead domain; similar to S. cerevisiae Hcm1p; Hap43p-induced gene || 1 -0.13 -0.56 -0.03 0.21 -2.66 -2.92 -0.36 0.42 -0.30 0.89 -0.24 0.31 0.02 -0.36 -2.02 -0.99
14155 || orf19.1115 || GUK1 || || Putative guanylate kinase; identified in extracts from biofilm and planktonic cells; protein level decrease in stationary phase cultures; Hap43p-induced gene || 1 -0.20 -0.31 -0.31 0.15 -1.89 -1.96 -0.29 0.07 -0.14 0.84 0.01 0.14 -0.22 -0.03 -1.50 -0.56
14156 || orf19.6846 || PHO85 || || Functional homolog of S. cerevisiae Pho85p, a cyclin-dependent kinase that regulates transcription of PHO genes involved in phosphate metabolism; necessary for geldanamycin-induced filamentation; gene has intron || 1 -0.29 -0.17 -0.27 -0.19 -1.07 -0.77 -0.17 0.01 0.01 -0.01 -0.16 -0.21 -0.45 -0.23 -0.95 0.15
14157 || orf19.2756 || || || Ortholog(s) have HDEL sequence binding activity, role in ER to Golgi vesicle-mediated transport, protein retention in ER lumen and Golgi apparatus, integral to endoplasmic reticulum membrane localization || 1 -0.42 -0.52 -0.29 -0.53 -1.60 -1.10 -0.20 0.14 -0.14 0.23 -0.14 0.03 -0.58 -0.37 -0.87 0.04
14158 || orf19.5352 || || || Protein with a predicted magnesium transporter domain; mutants are viable || 1 -0.49 -0.86 -0.19 -0.27 -1.60 -1.31 -0.55 -0.18 -0.24 0.24 -0.35 0.04 -0.72 0.24 -0.68 0.04
14159 || orf19.3086 || SEC10 || || Ortholog(s) have role in Golgi to plasma membrane transport, cytokinetic cell separation, exocytosis and cell cortex of cell tip, cell division site, cytosol, exocyst, mating projection tip, mitotic spindle pole body, nucleus localization || 1 -0.15 -0.39 -0.12 -0.13 -0.86 -0.86 -0.16 0.00 -0.25 -0.15 -0.02 -0.02 -0.32 0.19 -0.32 0.10
14160 || orf19.4378 || PPH3 || || Putative catalytic subunit of protein phosphatase complex; functions with regulatory subunit Psy2p in dephosphorylation of Rad53p in response to DNA damage; dephosphorylates Rfa2p in G1 phase; ortholog of S. cerevisiae Pph3p || 1 -0.36 -0.73 -0.09 0.00 -1.94 -2.19 -0.70 0.01 -0.64 -0.08 -0.01 0.00 -0.89 0.18 -1.22 0.34
14161 || orf19.3249 || LAG1 || || Putative ceramide synthase component; Hap43p-repressed gene; amphotericin B repressed || 1 -0.82 -0.85 -0.36 0.14 -1.57 -1.46 -0.41 0.05 -0.44 0.10 0.03 0.47 -0.91 -0.19 -0.89 0.22
14162 || orf19.1672 || || || Alpha subunit of COPI vesicle coatomer complex; role in ER to Golgi vesicle-mediated transport, retrograde vesicle-mediated transport, Golgi to ER transport; flow model biofilm repressed || 1 -0.51 -0.65 -0.31 -0.41 -1.19 -1.20 -0.17 -0.03 -0.28 -0.17 -0.08 -0.06 -0.59 -0.20 -0.54 0.43
14163 || orf19.3642 || SUN41 || || Cell wall glycosidase; role in biofilm formation and cell separation; possibly secreted; hypoxia, hyphal induced; caspofungin repressed; Efg1, Cph1 regulated; O-glycosylated, possible Kex2 substrate; 5'-UTR intron; Spider biofilm induced || 1 -0.81 -0.97 -0.71 0.06 -2.82 -2.38 -0.63 -0.50 -0.49 -0.04 0.19 0.15 -0.68 -0.69 -1.14 -0.16
14164 || orf19.3642 || SUN41 || || Cell wall glycosidase; role in biofilm formation and cell separation; possibly secreted; hypoxia, hyphal induced; caspofungin repressed; Efg1, Cph1 regulated; O-glycosylated, possible Kex2 substrate; 5'-UTR intron; Spider biofilm induced || 1 -0.73 -0.84 -0.74 0.04 -3.52 -2.66 -0.44 -0.37 -0.53 -0.01 0.33 0.04 -0.68 -0.71 -1.28 0.02
14165 || orf19.3086 || SEC10 || || Ortholog(s) have role in Golgi to plasma membrane transport, cytokinetic cell separation, exocytosis and cell cortex of cell tip, cell division site, cytosol, exocyst, mating projection tip, mitotic spindle pole body, nucleus localization || 1 -0.15 -0.26 -0.11 -0.12 -1.05 -0.86 -0.06 0.00 -0.19 -0.14 -0.07 -0.01 -0.10 -0.12 -0.23 0.03
14166 || orf19.1823 || || || Predicted membrane protein; transcript repressed by ciclopirox olamine || 1 -0.37 -0.38 -0.90 -0.42 -2.29 -2.44 0.31 0.54 -0.07 0.64 -0.25 -0.28 -0.51 0.37 -0.99 -0.61
14167 || orf19.1478 || STT3 || || Putative oligosaccharyltransferase complex component; flow model and rat catheter biofilm repressed || 1 -0.09 -0.18 -0.33 -0.15 -1.07 -1.21 0.15 0.25 -0.22 0.37 -0.09 -0.16 -0.35 0.10 -0.52 -0.38
14168 || orf19.1478 || STT3 || || Putative oligosaccharyltransferase complex component; flow model and rat catheter biofilm repressed || 1 -0.04 -0.02 -0.30 0.02 -0.91 -1.14 0.33 0.25 -0.15 0.38 -0.02 0.07 -0.50 -0.47 -0.37
14169 || orf19.556 || || || Protein of unknown function; regulated by Ssn6 || 1 0.01 -0.08 -0.30 0.66 -2.38 -2.28 -0.04 0.46 -0.06 0.60 -0.43 -0.48 -1.09 -0.04 -1.20 -0.91
14170 || orf19.1823 || || || Predicted membrane protein; transcript repressed by ciclopirox olamine || 1 -0.44 -0.52 -0.26 0.27 -2.03 -2.14 -0.09 0.41 0.25 0.84 -0.27 -0.33 -0.67 0.05 -1.44 -0.22
14171 || orf19.5013 || AGM1 || || Phosphoacetylglucosamine mutase (N-acetylglucosamine-phosphate mutase); enzyme of UDP-N-acetylglucosamine (UDP-GlcNAc) biosynthesis || 1 -0.27 -0.23 -0.27 0.11 -2.21 -2.65 0.29 0.40 -0.18 0.33 0.09 -0.47 -0.87 0.04 -1.45 -0.41
14172 || orf19.5015 || MYO2 || || Class V myosin; nonessential; sole class V myosin in C. albicans; required for WT actin cytoskeletal polarity, nuclear organization, migration, hyphal growth; conserved myosin ATPase/tail domains; Hap43-induced; flow model biofilm repressed || 1 -0.12 -0.21 -0.05 0.49 -2.13 -2.56 0.17 0.51 -0.28 0.70 -0.11 -0.11 -0.52 -0.23 -1.39 0.05
14173 || orf19.2799 || GPI8 || || Protein similar to S. cerevisiae Gpi8p, which is a subunit of the GPI transamidase complex that adds GPI anchors to proteins; likely to be essential for growth, based on an insertional mutagenesis strategy || 1 -0.10 -0.38 0.03 0.13 -1.23 -1.45 -0.19 0.24 -0.10 0.28 -0.34 -0.25 -0.42 -0.14 -0.76 -0.06
14174 || orf19.6264.3 || || || Ortholog(s) have role in ER to Golgi vesicle-mediated transport and ER to Golgi transport vesicle, Golgi apparatus, endoplasmic reticulum localization || 1 -0.08 -0.26 0.29 0.39 -1.78 -1.95 -0.28 0.22 -0.44 0.20 -0.16 -0.23 -0.65 0.00 -0.90 -0.34
14175 || orf19.6264.3 || || || Ortholog(s) have role in ER to Golgi vesicle-mediated transport and ER to Golgi transport vesicle, Golgi apparatus, endoplasmic reticulum localization || 1 -0.50 -0.56 -0.17 0.25 -1.97 -2.02 -0.34 0.14 -0.58 0.24 -0.09 -0.18 -0.72 0.03 -0.97 -0.42
14176 || orf19.4579 || ERV29 || || Putative SURF4 family member; plasma membrane-localized; flow model biofilm repressed || 1 -0.27 -0.34 0.27 0.81 -2.87 -2.13 -0.38 0.27 -0.09 0.33 -0.25 -0.26 -0.73 -0.16 -1.01 -0.19
14177 || orf19.7426 || || || Ortholog(s) have dolichyl-diphosphooligosaccharide-protein glycotransferase activity, role in protein N-linked glycosylation via asparagine, protein complex assembly and oligosaccharyltransferase complex localization || 1 -0.48 -0.66 0.12 0.40 -2.16 -1.88 -0.45 0.25 0.23 0.62 -0.27 -0.03 -0.44 0.18 -0.98 -0.53
14178 || orf19.5491 || || || Ortholog of C. dubliniensis CD36 : Cd36_20670, C. parapsilosis CDC317 : CPAR2_104720, Candida tenuis NRRL Y-1498 : CANTEDRAFT_103989 and Debaryomyces hansenii CBS767 : DEHA2F02046g || 1 -0.18 -0.31 -0.36 -0.02 -1.15 -1.18 -0.09 0.00 -0.53 0.00 -0.13 -0.16 -0.19 0.48 -0.86 0.17
14179 || orf19.6072 || CDC13 || || Essential protein with similarity to S. cerevisiae Cdc13p, involved in telomere maintenance || 1 -0.23 -0.28 -0.27 0.27 -1.29 -1.59 -0.28 0.08 -0.48 0.32 -0.09 -0.23 -0.58 0.47 -1.24 -0.59
14180 || orf19.5487 || CDC46 || || Putative hexameric MCM complex subunit; predicted role in control of cell division; periodic mRNA expression. peak at cell-cycle M/G1 phase; regulated by tyrosol, cell density, Plc1; repressed by alpha pheromone in SpiderM medium || 1 -0.97 -1.17 -0.29 -0.03 -2.70 -3.73 -0.86 -0.10 -0.99 0.42 0.34 -1.04 -0.79 -0.49 -2.88 -1.02
14181 || orf19.5873 || POL1 || || Putative DNA directed DNA polymerase alpha; RNA abundance regulated by cell cycle, tyrosol and cell density; rat catheter biofilm induced || 1 -0.48 -0.61 -0.03 0.11 -1.91 -2.66 -0.49 0.37 -0.79 0.42 0.12 -1.06 -1.16 0.14 -1.83 -0.66
14182 || orf19.3013 || CDC12 || || Septin; essential for viability; forms ring at sites of cell division and also forms filaments in mature chlamydospore; filamentous growth induced; regulated by Nrg1, Tup1, tyrosol and cell density; rat catheter biofilm repressed || 1 -0.08 -0.10 0.10 0.18 -1.38 -1.76 -0.15 0.21 -0.30 0.49 -0.08 -0.42 -0.42 0.10 -1.46 -0.44
14183 || orf19.3965 || || || Ortholog(s) have role in double-strand break repair via homologous recombination, meiotic gene conversion, reciprocal meiotic recombination, replication fork protection and Smc5-Smc6 complex, cytosol, nucleus localization || 1 -0.31 -0.28 0.04 0.18 -1.34 -1.58 -0.08 0.11 -0.24 0.46 -0.34 -0.64 -0.11 -0.05 -1.35 -0.72
14184 || orf19.6634 || VMA2 || || Vacuolar H(+)-ATPase; protein present in exponential and stationary growth phase yeast cultures; plasma membrane localized; amphotericin B repressed, caspofungin repressed || 1 -0.15 -0.22 -0.02 0.13 -0.86 -0.78 0.05 0.09 0.24 0.16 0.04 -0.25 -0.14 0.19 -0.70 -0.19
14185 || orf19.5941 || || || Ortholog(s) have role in ER to Golgi vesicle-mediated transport and ER to Golgi transport vesicle, integral to Golgi membrane, integral to endoplasmic reticulum membrane localization || 1 -0.27 -0.29 0.06 0.09 -1.10 -1.29 0.17 0.40 0.28 0.12 -0.10 -0.16 -0.22 0.29 -0.85 -0.47
14186 || orf19.7446 || OPI3 || || Phosphatidylethanolamine N-methyltransferase; phosphatidylcholine biosynthesis; downregulation correlates with clinical development of fluconazole resistance; amphotericin B, caspofungin repressed; Hap43-induced; Spider biofilm repressed || 1 -0.20 -0.43 -0.61 -0.20 -2.27 -3.00 0.26 1.07 -0.14 0.16 0.11 -0.17 -0.44 0.58 -2.26 -0.56
14187 || orf19.1631 || ERG6 || || Delta(24)-sterol C-methyltransferase, converts zymosterol to fecosterol, ergosterol biosynthesis; mutation confers nystatin resistance; Hap43, GlcNAc-, fluconazole-induced; upregulated in azole-resistant strain; Spider biofilm repressed || 1 -0.88 -0.82 -0.78 -0.01 -3.27 -2.70 -0.04 0.93 -0.10 0.65 -0.01 -0.37 -0.39 0.21 -2.86 -0.77
14188 || orf19.2937 || PMM1 || || Phosphomannomutase; enzyme of O- and N-linked mannosylation; interconverts mannose-6-phosphate and mannose-l-phosphate; functional homolog of S. cerevisiae Sec53; antigenic in mice; Hap43-induced; flow model and Spider biofilm repressed || 1 -0.26 0.09 -0.25 0.09 -2.03 -1.74 -0.13 0.12 -0.75 -0.41 0.17 -0.25 -0.65 0.00 -1.46 -0.05
14189 || orf19.3549 || CDC21 || || Putative thymidylate synthase; flucytosine induced; rat catheter biofilm repressed; Spider biofilm repressed || 1 -0.28 -0.22 -0.40 0.07 -1.65 -2.09 -0.29 0.63 -0.92 0.12 0.45 -0.52 -1.17 0.20 -1.88 0.04
14190 || orf19.2483 || RIM1 || || Putative single-stranded DNA-binding protein; protein level decreases in stationary phase cultures; rat catheter biofilm repressed || 1 -0.20 -0.27 -0.33 -0.28 -1.27 -1.62 -0.09 0.31 -0.52 -0.28 0.22 -0.27 -0.46 0.24 -1.49 -0.19
14191 || orf19.5379 || ERG4 || || Protein similar to sterol C-24 reductase; shows Mob2p-dependent hyphal regulation; fluconazole-induced; caspofungin repressed; rat catheter biofilm repressed || 1 -0.25 -0.22 -0.12 -0.09 -1.42 -1.59 0.07 0.16 -0.19 -0.03 0.11 -0.09 -0.64 0.32 -1.08 0.14
14192 || orf19.1064 || ACS2 || || Acetyl-CoA synthetase; antigenic during human and murine infection; induced by Efg1; macrophage-induced protein; soluble protein in hyphae; gene contains intron; flow model and Spider biofilm repressed || 1 -0.30 -0.33 -0.57 -0.15 -1.98 -2.01 0.08 0.42 -0.18 -0.00 0.40 0.07 -1.18 -0.14 -1.60 0.10
14193 || orf19.7425 || || || Ortholog(s) have uracil DNA N-glycosylase activity, role in DNA repair and mitochondrion, nucleus localization || 1 -0.38 -0.36 -0.74 -0.40 -1.17 -2.33 0.24 0.69 -0.05 0.50 -0.02 -0.69 -0.52 -0.03 -1.41 -0.56
14194 || orf19.3013 || CDC12 || || Septin; essential for viability; forms ring at sites of cell division and also forms filaments in mature chlamydospore; filamentous growth induced; regulated by Nrg1, Tup1, tyrosol and cell density; rat catheter biofilm repressed || 1 -0.13 -0.05 -0.27 -0.30 -1.01 -1.87 0.05 0.22 -0.28 0.45 0.09 -0.60 -0.24 0.07 -1.17 -0.28
14195 || orf19.3013 || CDC12 || || Septin; essential for viability; forms ring at sites of cell division and also forms filaments in mature chlamydospore; filamentous growth induced; regulated by Nrg1, Tup1, tyrosol and cell density; rat catheter biofilm repressed || 1 -0.27 -0.20 -0.35 -0.24 -1.06 -1.56 -0.17 0.12 -0.11 0.56 -0.01 -0.39 -0.41 0.37 -1.12 -0.34
14196 || orf19.2611 || MCM6 || || Putative MCM DNA replication initiation complex component; mRNA expression peak at cell-cycle M/G1 phase; regulated by tyrosol and cell density; repressed by alpha pheromone in SpiderM medium; Hap43-induced gene || 1 -1.06 -0.87 -1.30 -0.47 -2.55 -4.26 -0.01 0.47 -0.79 0.86 0.85 -0.79 -0.65 0.35 -2.38 -0.66
14197 || orf19.2267 || RFA2 || || Putative DNA replication factor A; RNA abundance regulated by cell cycle, tyrosol and cell density || 1 -0.70 -0.82 -0.99 -0.66 -1.86 -2.99 -0.13 0.76 -0.87 0.17 0.67 -0.54 -0.52 0.20 -1.34 -0.74
14198 || orf19.2322.3 || ERP5 || || Protein involved in ER to Golgi transport; rat catheter and Spider biofilm repressed || 1 -0.32 -0.32 -0.94 -0.68 -1.76 -2.53 0.25 0.76 -0.84 0.10 0.41 -0.62 -0.64 -0.29 -1.64 -0.44
14199 || orf19.2322.3 || ERP5 || || Protein involved in ER to Golgi transport; rat catheter and Spider biofilm repressed || 1 -0.02 -0.26 -0.44 -0.18 -1.46 -2.03 0.30 0.83 -0.57 0.30 0.38 -0.33 -0.86 -0.07 -1.39 -0.25
14200 || orf19.2166 || VMA5 || || Putative vacuolar H(+)-ATPase; plasma membrane localized; rat catheter biofilm repressed || 1 -0.14 -0.32 -0.38 -0.24 -1.44 -1.22 -0.19 0.25 -0.28 -0.17 -0.35 -0.41 -0.31 -0.15 -1.03 -0.21
14201 || orf19.2166 || VMA5 || || Putative vacuolar H(+)-ATPase; plasma membrane localized; rat catheter biofilm repressed || 1 -0.19 -0.28 -0.41 -0.04 -1.35 -1.50 -0.34 0.21 -0.17 -0.06 -0.30 -0.31 -0.36 -0.01 -1.15 -0.29
14202 || orf19.5384 || CHS8 || || Chitin synthase required for synthesis of long-chitin fibrils; nonessential; 8 or 9 membrane spanning regions; mRNA present in yeast and hyphae; induced during cell wall regeneration; flow model biofilm repressed || 1 -0.29 -0.43 -0.64 -0.22 -2.39 -2.48 -0.06 0.10 -0.55 -0.26 -0.19 -0.68 -0.52 0.07 -1.48 -0.38
14203 || orf19.2166 || VMA5 || || Putative vacuolar H(+)-ATPase; plasma membrane localized; rat catheter biofilm repressed || 1 -0.25 -0.39 -0.63 -0.37 -1.35 -1.57 -0.18 0.22 -0.38 -0.20 -0.20 -0.35 -0.37 0.08 -0.93 -0.57
14204 || orf19.5015 || MYO2 || || Class V myosin; nonessential; sole class V myosin in C. albicans; required for WT actin cytoskeletal polarity, nuclear organization, migration, hyphal growth; conserved myosin ATPase/tail domains; Hap43-induced; flow model biofilm repressed || 1 -1.04 -1.12 -1.41 -0.92 -3.28 -3.85 -0.35 -0.02 -1.06 0.13 -0.57 -1.25 -1.01 -0.43 -2.45 -0.72
14205 || orf19.5238 || || || Ortholog(s) have cytosol, nucleus localization || 1 -0.37 -0.43 -1.09 -0.58 -1.93 -2.18 -0.06 0.09 -0.26 0.33 -0.70 -0.73 -0.61 -0.09 -1.46 -0.22
14206 || orf19.5238 || || || Ortholog(s) have cytosol, nucleus localization || 1 -0.45 -0.58 -0.83 -0.33 -2.01 -2.19 -0.10 0.27 -0.26 0.53 -0.77 -0.45 -0.99 -0.20 -1.37 -0.38
14207 || orf19.1631 || ERG6 || || Delta(24)-sterol C-methyltransferase, converts zymosterol to fecosterol, ergosterol biosynthesis; mutation confers nystatin resistance; Hap43, GlcNAc-, fluconazole-induced; upregulated in azole-resistant strain; Spider biofilm repressed || 1 -0.52 -0.70 -0.99 -0.83 -2.00 -2.42 0.17 0.79 -0.42 0.41 -0.01 -0.56 -0.49 0.42 -1.79 -0.36
14208 || orf19.7446 || OPI3 || || Phosphatidylethanolamine N-methyltransferase; phosphatidylcholine biosynthesis; downregulation correlates with clinical development of fluconazole resistance; amphotericin B, caspofungin repressed; Hap43-induced; Spider biofilm repressed || 1 -0.70 -0.88 -1.27 -0.70 -2.58 -3.11 -0.10 0.48 -0.51 -0.12 -0.26 -0.32 -0.92 0.76 -1.91 0.04
14209 || orf19.5779 || RNR1 || || Ribonucleotide reductase large subunit; induced in low iron; transposon mutation affects filamentous growth; farnesol upregulated in biofilm; regulated by cell cycle, tyrosol, cell density; regulated by Sef1, Sfu1, and Hap43 || 1 -0.77 -0.96 -1.00 -0.69 -2.80 -3.34 -0.42 0.47 -1.28 -0.21 0.19 -1.00 0.08 0.71 -1.97 -0.22
14210 || orf19.5528 || MOB1 || || Putative mitotic exit network component; periodic mRNA expression, peak at cell-cycle G2/M phase || 1 -0.28 -0.38 -0.75 -0.35 -2.31 -1.49 0.02 0.29 -0.63 -0.25 0.07 -0.38 -0.39 0.10 -1.16 0.03
14211 || orf19.5188 || CHS1 || || Chitin synthase; essential; for primary septum synthesis in yeast and hyphae; 1 of several chitin synthases; enzymatically activated by proteolytic processing; complements defects of S. cerevisiae chs1 or chs2; Spider biofilm repressed || 1 -0.60 -0.82 -0.50 0.08 -2.89 -2.30 0.11 0.30 -0.23 0.10 -0.08 -0.30 -0.29 -0.04 -1.56 -0.16
14212 || orf19.3752 || RAD51 || || Protein involved in homologous recombination and DNA repair; flucytosine induced; slow growth and increased white-to-opaque switching frequency in null mutant || 1 -0.61 -0.76 -0.46 -0.57 -3.35 -3.45 -0.19 0.18 -0.60 0.23 -0.10 -0.45 -0.48 0.39 -1.83 0.05
14213 || orf19.4257 || INT1 || || Protein structurally similar to alpha-subunit of human leukocyte integrin; role in morphogenesis, adhesion, and mouse cecal colonization and systemic virulence; similar to S. cerevisiae Bud4; Hap43-induced gene || 1 -0.62 -0.61 -0.56 -0.07 -2.78 -2.88 -0.02 0.19 -0.63 -0.13 0.06 -0.44 -0.02 0.15 -2.06 -0.28
14214 || orf19.5779 || RNR1 || || Ribonucleotide reductase large subunit; induced in low iron; transposon mutation affects filamentous growth; farnesol upregulated in biofilm; regulated by cell cycle, tyrosol, cell density; regulated by Sef1, Sfu1, and Hap43 || 1 -1.10 -1.16 -1.07 -0.74 -4.60 -3.72 -0.43 0.54 -1.30 0.17 0.32 -0.82 -0.09 0.75 -2.81 -0.28
14215 || orf19.5188 || CHS1 || || Chitin synthase; essential; for primary septum synthesis in yeast and hyphae; 1 of several chitin synthases; enzymatically activated by proteolytic processing; complements defects of S. cerevisiae chs1 or chs2; Spider biofilm repressed || 1 -0.62 -0.92 -1.45 -0.67 -3.28 -2.74 -0.04 0.14 -0.50 0.02 0.09 -0.60 -0.11 -0.05 -1.45 -0.11
14216 || orf19.1893 || || || Protein of unknown function; Spider biofilm repressed || 1 -0.14 -0.19 -0.68 -0.33 -1.76 -1.70 0.12 0.02 -0.11 0.20 -0.09 -0.27 0.05 -0.07 -0.68 0.10
14217 || orf19.3558 || || || Ortholog(s) have Golgi apparatus, endoplasmic reticulum localization || 1 -1.12 -1.05 -0.52 -0.28 -2.09 -2.30 -0.17 0.51 -0.81 0.05 0.31 0.07 -0.83 -0.22 -1.83 -0.29
14218 || orf19.4945 || MSH6 || || Protein similar to S. cerevisiae Msh6p, which is involved in mismatch repair; repressed under Cdc5p depletion; Hap43p-induced gene || 1 -1.17 -1.18 -0.66 0.00 -2.48 -2.78 -0.89 0.40 -0.64 0.50 0.35 -0.57 0.27 -2.37 -0.11
14219 || orf19.4945 || MSH6 || || Protein similar to S. cerevisiae Msh6p, which is involved in mismatch repair; repressed under Cdc5p depletion; Hap43p-induced gene || 1 -0.87 -1.01 -0.51 -0.02 -1.86 -2.80 -0.63 0.55 -0.87 0.26 0.23 -0.26 -0.41 0.23 -1.87 -0.03
14220 || orf19.2267 || RFA2 || || Putative DNA replication factor A; RNA abundance regulated by cell cycle, tyrosol and cell density || 1 -0.44 -0.51 -0.39 -0.14 -1.50 -2.54 -0.15 0.84 -0.89 0.37 0.61 -0.01 -0.54 0.23 -1.12 0.36
14221 || orf19.4616 || POL30 || || Similar to proliferating cell nuclear antigen (PCNA); RNA abundance regulated by tyrosol, cell density; induced by flucytosine, interaction with macrophages; stationary phase enriched protein; rat catheter and Spider biofilm repressed || 1 -1.24 -1.14 -1.09 -0.50 -3.44 -3.85 -0.28 1.09 -1.04 0.16 1.51 0.06 -1.06 0.18 -2.49 0.52
14222 || orf19.4616 || POL30 || || Similar to proliferating cell nuclear antigen (PCNA); RNA abundance regulated by tyrosol, cell density; induced by flucytosine, interaction with macrophages; stationary phase enriched protein; rat catheter and Spider biofilm repressed || 1 -1.21 -1.23 -0.70 -0.43 -2.56 -3.40 -0.30 0.89 -1.03 0.19 1.46 0.48 -1.00 0.21 -2.10 0.04
14223 || orf19.6078.1 || RFC52 || || Putative replication factor C complex protein; periodic mRNA expression, peak at cell-cycle G1/S phase; overlaps orf19.6079 || 1 -0.96 -0.95 -0.94 -0.46 -1.65 -2.85 -0.16 0.55 -0.95 0.46 0.94 -0.16 -1.16 -0.06 -1.73 0.17
14224 || orf19.7658 || RFC4 || || Putative heteropentameric replication factor C subunit; flucytosine induced; periodic mRNA expression, peak at cell-cycle G1/S phase || 1 -0.37 -0.54 -0.57 -0.07 -1.14 -1.80 -0.27 0.45 -0.73 0.52 0.44 -0.30 -0.68 -0.05 -0.82 0.00
14225 || orf19.5658 || MNN10 || || Ortholog(s) have alpha-1,6-mannosyltransferase activity, role in ascospore formation, barrier septum assembly and alpha-1,6-mannosyltransferase complex localization || 1 -0.41 -0.55 -0.62 0.04 -0.95 -1.58 -0.25 0.14 -0.65 0.15 -0.14 -0.29 -0.50 0.10 -0.50 -0.30
14226 || orf19.3957 || || || Ortholog(s) have GTP cyclohydrolase I activity, role in folic acid-containing compound biosynthetic process and cytosol, nucleus localization || 1 -0.45 -0.50 -0.74 -0.50 -1.16 -1.21 -0.24 0.38 -0.49 0.51 -0.09 -0.24 -0.56 0.29 -0.94 -0.29
14227 || orf19.3957 || || || Ortholog(s) have GTP cyclohydrolase I activity, role in folic acid-containing compound biosynthetic process and cytosol, nucleus localization || 1 -0.27 -0.27 -0.80 -0.53 -0.94 -1.39 -0.27 0.28 -0.53 0.35 -0.13 -0.51 -0.31 0.32 -0.83 -0.56
14228 || orf19.6787 || || || Ortholog(s) have role in ER to Golgi vesicle-mediated transport, ascospore formation, axial cellular bud site selection and ER to Golgi transport vesicle, endoplasmic reticulum membrane localization || 1 -0.49 -0.56 -0.82 -0.45 -1.18 -1.20 -0.32 0.31 -0.61 0.05 -0.07 -0.21 -0.53 0.36 -0.73 -0.88
14229 || orf19.908 || FEN12 || || Putative protein with a predicted role in the elongation of fatty acids; amphotericin B, caspofungin repressed || 1 -0.43 -0.31 -0.63 -0.33 -1.33 -2.25 0.25 0.49 -0.51 0.21 -0.07 -0.80 0.41 0.20 -1.01 -0.41
14230 || orf19.1265 || || || Ortholog(s) have Rab guanyl-nucleotide exchange factor activity and role in CVT pathway, early endosome to Golgi transport, intra-Golgi vesicle-mediated transport, macroautophagy, regulation of Rab GTPase activity || 1 -0.02 0.13 -0.67 -0.35 -0.73 -1.89 -0.06 0.21 -0.44 0.22 0.18 -0.53 -0.04 -0.02 -0.83 0.22
14231 || orf19.2328 || || || Ortholog of C. dubliniensis CD36 : Cd36_10220, C. parapsilosis CDC317 : CPAR2_210530, Candida tenuis NRRL Y-1498 : CANTEDRAFT_105553 and Debaryomyces hansenii CBS767 : DEHA2G14432g || 1 -0.05 -0.11 -0.26 -0.45 -0.94 -1.54 -0.16 0.32 -0.50 -0.13 0.23 -0.07 -0.05 -0.12 -0.62 0.11
14232 || orf19.306 || USO5 || || Putative type II myosin heavy chain; transcription is induced upon filamentous growth and in response to alpha pheromone in SpiderM medium || 1 0.09 0.10 -0.35 -0.22 -0.99 -1.36 0.17 0.06 -0.56 -0.23 0.13 -0.26 0.42 -0.14 -0.69 -0.13
14233 || orf19.5006 || GCV3 || || Glycine decarboxylase, subunit H; protein level decrease in stationary phase cultures || 1 0.22 -0.15 -0.95 -0.60 -1.90 -2.08 0.06 0.16 -0.36 -0.46 0.02 -0.45 -0.65 -0.37 -1.28 -0.77
14234 || orf19.2483 || RIM1 || || Putative single-stranded DNA-binding protein; protein level decreases in stationary phase cultures; rat catheter biofilm repressed || 1 -0.07 -0.32 -0.54 -0.46 -1.41 -1.88 0.06 0.41 -0.77 -0.62 0.30 -0.71 -0.19 -0.10 -1.55 -1.16
14235 || orf19.7238 || NPL3 || || Putative RNA-binding protein; required for normal flow model biofilm growth; nuclear export is facilitated by Hmt1p; transcript upregulated in RHE model of oralcandidiasis; Spider biofilm repressed || 1 -0.21 -0.14 -0.74 -0.34 -0.80 -1.21 0.33 0.51 -0.42 0.06 0.01 -0.74 -0.14 -0.23 -1.23 -0.35
14236 || orf19.244 || DCG1 || || Protein of unknown function; ortholog of S. cerevisiae Dcg1; transcript regulated by Nrg1 and Mig1 || 1 -0.03 0.16 0.05 0.20 -0.46 -1.54 -0.02 0.64 -0.43 0.46 -0.17 -0.31 -0.04 -0.25 -0.53 -0.17
14237 || orf19.7658 || RFC4 || || Putative heteropentameric replication factor C subunit; flucytosine induced; periodic mRNA expression, peak at cell-cycle G1/S phase || 1 -0.10 -0.13 0.01 -0.06 -0.64 -1.19 -0.35 0.26 -0.35 0.52 0.16 -0.42 -0.28 0.09 -0.25 0.00
14238 || orf19.2796 || || || Ortholog(s) have DNA-directed DNA polymerase activity, role in DNA replication initiation, telomere capping and alpha DNA polymerase:primase complex, cytosol, nuclear envelope localization || 1 -0.28 -0.36 0.10 0.05 -0.63 -2.04 -0.10 0.18 -0.37 0.97 0.32 -0.41 -0.45 0.28 -0.69 -0.16
14239 || orf19.2796 || || || Ortholog(s) have DNA-directed DNA polymerase activity, role in DNA replication initiation, telomere capping and alpha DNA polymerase:primase complex, cytosol, nuclear envelope localization || 1 -0.42 -0.18 0.05 0.15 -0.79 -2.27 -0.18 0.46 -0.17 1.11 0.41 -0.54 -0.22 0.57 -1.57 -0.00
14240 || orf19.7634 || MCD1 || || Alpha-kleisin cohesin complex subunit; for sister chromatid cohesion in mitosis and meiosis; repressed by alpha pheromone in SpiderM medium; periodic cell-cycle expression; Hap43-repressed; rat catheter and Spider biofilm repressed || 1 0.26 0.17 -0.22 0.30 -1.27 -2.49 0.07 0.74 -0.57 1.20 0.87 -0.15 0.51 0.43 -1.28 -0.38
14241 || orf19.7634 || MCD1 || || Alpha-kleisin cohesin complex subunit; for sister chromatid cohesion in mitosis and meiosis; repressed by alpha pheromone in SpiderM medium; periodic cell-cycle expression; Hap43-repressed; rat catheter and Spider biofilm repressed || 1 0.38 0.18 -0.01 0.37 -1.50 -2.50 0.05 0.84 -0.70 0.69 0.67 -0.28 0.39 0.33 -0.98 -0.71
14242 || orf19.663 || GIN4 || || Autophosphorylated kinase; role in pseudohyphal-hyphal switch and cytokinesis; phosphorylates Cdc11p on S395; necessary for septin ring within germ tube but not for septin band at mother cell junction; physically associates with septins || 1 -0.14 0.04 0.00 0.25 -1.69 -2.47 0.04 0.35 -0.26 0.61 0.10 -0.40 0.19 0.31 -1.25 -0.60
14243 || orf19.5487 || CDC46 || || Putative hexameric MCM complex subunit; predicted role in control of cell division; periodic mRNA expression. peak at cell-cycle M/G1 phase; regulated by tyrosol, cell density, Plc1; repressed by alpha pheromone in SpiderM medium || 1 0.06 -0.01 -0.06 0.32 -1.44 -2.48 -0.29 0.02 -0.73 0.86 0.51 -0.42 0.23 0.20 -1.41 -0.63
14244 || orf19.4354 || MCM2 || || Phosphorylated protein of unknown function; transcription is periodic with a peak at M/G1 phase of the cell cycle || 1 0.32 0.26 -0.05 0.60 -1.14 -2.29 -0.04 0.26 -0.67 0.64 0.37 -0.63 -0.08 0.23 -1.51 -0.77
14245 || orf19.4354 || MCM2 || || Phosphorylated protein of unknown function; transcription is periodic with a peak at M/G1 phase of the cell cycle || 1 0.76 0.72 0.48 1.42 -1.69 -2.84 -0.11 0.62 -0.52 0.92 0.58 -0.62 0.09 -0.03 -1.72 -0.76
14246 || orf19.663 || GIN4 || || Autophosphorylated kinase; role in pseudohyphal-hyphal switch and cytokinesis; phosphorylates Cdc11p on S395; necessary for septin ring within germ tube but not for septin band at mother cell junction; physically associates with septins || 1 0.17 0.29 0.33 0.69 -0.86 -1.58 -0.33 -0.05 -0.47 0.45 -0.22 -0.24 0.17 0.23 -1.07 -0.63
14247 || orf19.3761 || CDC54 || || Putative pre-replication complex helicase subunit; transcript regulated by Nrg1 and Mig1; periodic mRNA expression, peak at cell-cycle M/G1 phase; Hap43-induced || 1 -0.06 0.01 0.12 0.87 -0.66 -1.49 -0.27 0.12 -0.26 0.80 -0.06 0.08 -0.13 0.35 -0.68 -0.50
14248 || orf19.5244 || MCD4 || || Protein of major facilitator superfamily; has phosphodiesterase/nucleotide pyrophosphatase domain; similar to S. cerevisiae Mcd4p, which acts in GPI anchor biosynthesis; possibly an essential gene, disruptants not obtained by UAU1 method || 1 -0.10 -0.23 0.12 0.28 -0.93 -2.16 -0.04 0.10 -0.30 0.50 -0.49 -0.55 -0.03 0.60 -1.16 -0.49
14249 || orf19.7190 || OGG1 || || Mitochondrial glycosylase/lyase; repairs oxidative damage to mitochondrial DNA, contributes to UVA resistance, role in base-excision repair; Spider biofilm induced || 1 0.11 0.20 -0.11 0.43 -0.87 -1.51 -0.26 0.14 -0.10 1.08 -0.35 -0.29 -0.09 -0.02 -0.61 -0.56
14250 || orf19.7083 || DCC1 || || Protein with a predicted role in sister chromatid cohesion and telomere length maintenance; cell-cycle regulated periodic mRNA expression || 1 -0.29 -0.33 -0.62 0.42 -0.76 -1.94 -0.15 0.33 -0.45 0.66 0.27 -0.22 -0.48 -0.33 -2.11 -0.81
14251 || orf19.1901 || MCM3 || || Putative DNA replication protein; periodic mRNA expression, peak at cell-cycle M/G1 phase; Spider biofilm induced || 1 -0.28 -0.24 -0.29 0.40 -1.45 -2.23 -0.11 0.56 -0.55 0.59 0.57 -0.41 -0.06 0.06 -2.16 -0.75
14252 || orf19.2611 || MCM6 || || Putative MCM DNA replication initiation complex component; mRNA expression peak at cell-cycle M/G1 phase; regulated by tyrosol and cell density; repressed by alpha pheromone in SpiderM medium; Hap43-induced gene || 1 -0.78 -0.46 0.20 0.10 -1.62 -1.66 -0.19 0.56 -0.20 0.81 0.65 -0.44 -0.05 0.16 -2.06 -0.58
14253 || orf19.5057 || || || Ortholog of C. dubliniensis CD36 : Cd36_07380 and Candida albicans WO-1 : CAWG_00634 || 1 -0.25 0.03 0.23 0.17 -0.40 -1.56 0.29 -0.15 -0.48 0.50 0.10 -0.08 -0.07 0.06 -0.90 -0.55
14254 || orf19.5006 || GCV3 || || Glycine decarboxylase, subunit H; protein level decrease in stationary phase cultures || 1 0.60 0.37 -0.23 0.06 -1.60 -1.86 0.51 0.85 -0.10 -0.36 0.62 -0.09 -0.16 -0.17 -0.94 -0.46
14255 || orf19.1251 || BRN1 || || Putative condensin complex subunit; cell-cycle regulated periodic mRNA expression || 1 0.67 0.57 0.01 0.05 -1.22 -1.52 0.44 0.46 -0.19 0.06 0.55 -0.01 0.09 0.12 -1.08 -0.93
14256 || orf19.2483 || RIM1 || || Putative single-stranded DNA-binding protein; protein level decreases in stationary phase cultures; rat catheter biofilm repressed || 1 0.14 0.02 -0.08 0.21 -1.16 -1.40 0.17 0.75 0.19 0.06 0.61 -0.06 -0.03 0.45 -1.40 -0.64
14257 || orf19.2483 || RIM1 || || Putative single-stranded DNA-binding protein; protein level decreases in stationary phase cultures; rat catheter biofilm repressed || 1 0.00 -0.05 -0.14 -0.01 -1.11 -1.37 0.10 0.48 -0.21 -0.42 0.57 -0.23 -0.14 0.30 -1.14 -0.48
14258 || orf19.2483 || RIM1 || || Putative single-stranded DNA-binding protein; protein level decreases in stationary phase cultures; rat catheter biofilm repressed || 1 0.01 -0.07 -0.11 0.04 -1.16 -1.40 0.22 0.51 -0.38 -0.27 0.55 -0.12 -0.30 0.40 -1.25 -0.02
14259 || orf19.1340 || || || Putative aldose reductase; protein level decreases in stationary phase cultures; Spider biofilm repressed || 1 0.44 0.35 -0.42 0.23 -2.32 -2.04 0.97 0.64 0.44 -0.10 0.42 0.20 -0.09 0.75 -1.87 0.50
14260 || orf19.6190 || SRB1 || || Essential GDP-mannose pyrophosphorylase; makes GDP-mannose for protein glycosylation; functional in S. cerevisiae psa1; on yeast-form, not hyphal cell surface; alkaline induced; induced on adherence to polystyrene; Spider biofilm repressed || 1 0.25 0.24 -1.91 -1.27 0.56 0.44 0.42 -0.04 0.40 0.09 -0.04 0.27 -1.45 0.20
14261 || orf19.3394 || || || Predicted membrane protein; induced by alpha pheromone in SpiderM medium || 1 -0.29 -0.46 0.54 0.31 -1.50 -1.49 -0.31 0.12 -0.15 0.02 -0.41 -0.19 0.69 0.07 -1.15 0.29
14262 || orf19.1185 || || || Ortholog(s) have protein homodimerization activity, ubiquitin-protein ligase activity || 1 -0.17 -0.24 0.70 0.22 -1.00 -1.05 -0.31 0.11 -0.40 -0.01 0.05 -0.21 -0.13 0.17 -0.63 -0.11
14263 || orf19.4444 || PHO15 || || 4-nitrophenyl phosphatase, possible histone H2A phosphatase; involved in regulation of white-opaque switch; hyphal repressed; induced in core stress response; induced by cadmium stress via Hog1; rat catheter and Spider biofilm repressed || 1 0.16 0.12 0.01 0.01 -1.74 -1.47 0.22 0.47 0.00 -0.87 0.17 -0.63 0.07 0.24 -2.90 0.38
14264 || orf19.4444 || PHO15 || || 4-nitrophenyl phosphatase, possible histone H2A phosphatase; involved in regulation of white-opaque switch; hyphal repressed; induced in core stress response; induced by cadmium stress via Hog1; rat catheter and Spider biofilm repressed || 1 -0.08 -0.17 -0.57 -0.42 -2.04 -1.84 0.16 0.26 -0.31 -0.99 -0.07 -0.40 -0.31 0.27 -2.81 0.72
14265 || orf19.4444 || PHO15 || || 4-nitrophenyl phosphatase, possible histone H2A phosphatase; involved in regulation of white-opaque switch; hyphal repressed; induced in core stress response; induced by cadmium stress via Hog1; rat catheter and Spider biofilm repressed || 1 -0.10 -0.12 -0.34 -0.31 -2.20 -1.86 0.18 0.34 -0.34 -0.94 -0.19 -0.54 -0.22 0.17 -3.08 0.17
14266 || orf19.4444 || PHO15 || || 4-nitrophenyl phosphatase, possible histone H2A phosphatase; involved in regulation of white-opaque switch; hyphal repressed; induced in core stress response; induced by cadmium stress via Hog1; rat catheter and Spider biofilm repressed || 1 -0.01 -0.02 -0.72 -0.95 -2.06 -2.15 0.34 0.22 -0.59 -1.29 -0.05 -0.83 -0.24 0.08 -2.88 0.09
14267 || orf19.3356 || ESP1 || || Putative caspase-like cysteine protease; mutation confers increased sensitivity to nocodazole; periodic mRNA expression, peak at cell-cycle S/G2 phase; mRNA binds She3 || 1 0.24 0.41 -0.04 -0.21 -1.07 -1.35 -0.03 0.09 -0.24 -0.20 -0.02 -0.12 0.03 0.01 -1.33 0.13
14268 || orf19.1964 || || || Protein of unknown function; repressed by fluphenazine treatment; induced by benomyl treatment and in an RHE model; regulated by Nrg1, Tup1 || 1 -0.18 -0.19 -0.22 -0.31 -1.29 -1.59 0.00 -0.33 0.06 -0.31 -0.18 -0.06 0.31 -0.06 -1.07 0.08
14269 || orf19.122 || CDC20 || || Activator of anaphase-promoting complex/cyclosome; induced under Cdc5 depletion; member of conserved Mcm1 regulon; mRNA expression peaks at cell-cycle G2/M phase; mRNA binds She3 and is localized to buds of yeast cells and to hyphal tips || 1 -0.07 -0.27 -0.25 -0.24 -0.82 -0.90 -0.05 -0.01 -0.02 -0.06 -0.07 0.04 -0.10 0.09 -0.89 0.43
14270 || orf19.486 || NIP100 || || p150 subunit of dynactin; required for normal spindle formation and position || 1 -0.33 -0.27 -0.21 -0.48 -0.59 -0.97 0.13 -0.08 -0.04 -0.33 -0.28 -0.34 -0.08 0.33 -0.97 0.41
14271 || orf19.2907 || PGA42 || || Putative GPI-anchored adhesin-like protein; decreased transcription is observed in azole-resistant strains that overexpress CDR1 and CDR2 or MDR1 || 1 -0.20 0.29 -0.10 -1.71 -0.63 -0.34 0.51 0.96 -0.33 -1.10 -0.64 -1.63 -0.47
14272 || orf19.3765 || RAX2 || || Plasma membrane protein involved in establishment of bud sites and linear direction of hyphal growth; filament induced, repressed by Rim101, Tup1; Hap43-induced; Spider biofilm induced || 1 -0.10 0.13 -0.17 0.05 -0.39 -0.85 -0.29 -0.23 -0.14 0.58 -0.78 -0.72 -0.13 0.05 -1.12 -0.73
14273 || orf19.2673 || || || Ortholog(s) have role in DNA repair and Smc5-Smc6 complex, cytoplasm, nucleus localization || 1 -0.18 0.04 -0.14 0.13 -0.53 -1.08 -0.42 0.16 -0.44 1.03 -0.05 -0.97 0.03 -0.06 -1.13 -0.99
14274 || orf19.7494 || || || Protein of unknown function; cell-cycle regulated periodic mRNA expression || 1 0.09 -0.09 -0.16 0.42 -0.50 -1.02 -0.20 0.31 -0.18 0.74 -0.16 -0.66 -0.37 0.51 -0.75 -0.41
14275 || orf19.4162 || MLH1 || || Putative mismatch repair protein; cell-cycle regulated periodic mRNA expression || 1 -0.14 0.21 -0.33 0.15 0.05 -1.32 -0.28 -0.04 -0.34 0.93 -0.39 -0.72 -0.11 0.37 -0.28 -0.62
14276 || orf19.6568 || SMC6 || || Putative structural maintenance of chromosomes (SMC) protein; Hap43-induced; cell-cycle regulated periodic mRNA expression; S. cerevisiae ortholog not cell-cycle regulated; Spider biofilm induced || 1 0.45 0.30 0.28 0.57 0.05 -0.96 -0.12 0.56 -0.80 0.63 0.24 0.00 -0.29 0.28 -0.65 -0.06
14277 || orf19.3093 || MSH2 || || Putative DNA mismatch repair factor; transcript regulated by Nrg1; flucytosine repressed; transcript regulated by tyrosol and cell density || 1 0.09 -0.05 0.21 0.24 -0.17 -0.50 -0.29 0.16 -0.41 0.50 -0.00 -0.19 -0.32 0.35 -0.47 0.11
14278 || orf19.5073 || DPM1 || || Putative dolichol phosphate mannose synthase; filament induced; Tup1-regulated; flow model and rat catheter biofilm repressed || 1 -0.07 -0.11 0.10 0.09 -0.30 -0.73 -0.39 -0.22 -0.37 0.13 -0.11 -0.11 -0.64 -0.27 -0.65 -0.05
14279 || orf19.3581 || || || Ortholog(s) have histone binding activity, role in DNA replication-dependent nucleosome assembly and CAF-1 complex, cytoplasm, nucleus localization || 1 -0.19 -0.06 0.13 0.49 -0.90 -1.08 -0.52 -0.14 -0.37 0.71 -0.19 -0.01 -0.63 -0.35 -1.01 -0.21
14280 || orf19.1391 || || || Protein with similarity to trimeric LpxA-like enzymes; Hap43-repressed gene || 1 0.22 -0.01 0.41 0.44 -0.56 -1.13 -0.22 0.35 -0.33 0.52 0.02 -0.25 -0.92 -0.34 -1.09 -0.06
14281 || orf19.2365 || POL2 || || DNA polymerase epsilon; transcript induced by interaction with macrophage; transcript is regulated by Tup1; periodic mRNA expression, peak at cell-cycle G1/S phase || 1 0.07 0.09 0.41 0.18 -0.73 -1.08 -0.37 0.44 -0.03 0.44 0.56 -0.12 -0.74 0.25 -1.56 0.14
14282 || orf19.2365 || POL2 || || DNA polymerase epsilon; transcript induced by interaction with macrophage; transcript is regulated by Tup1; periodic mRNA expression, peak at cell-cycle G1/S phase || 1 0.19 -0.05 0.08 0.07 -0.92 -1.25 -0.49 0.22 -0.41 0.06 0.41 -1.10 -0.79 -0.14 -1.77 -0.31
14283 || orf19.964 || SMC4 || || Ortholog(s) have chromatin binding activity and role in cellular protein localization, mitotic chromosome condensation, tRNA gene clustering || 1 0.22 0.28 0.56 0.57 -0.59 -0.81 -0.14 0.17 -0.22 0.22 0.23 -0.09 -0.15 -0.14 -1.16 0.05
14284 || orf19.7151 || || || Ortholog of Candida albicans WO-1 : CAWG_05751 || 1 0.91 0.49 1.16 1.08 -0.87 -2.21 -0.73 0.13 -0.81 0.08 0.48 -0.77 -1.09 -0.23 -1.78 -0.62
14285 || orf19.5711 || || || Putative phosphatidylinositol transfer protein; possibly an essential gene, disruptants not obtained by UAU1 method || 1 0.96 1.01 0.53 1.07 -0.83 -1.57 -0.21 0.24 -0.51 0.25 -0.23 -0.56 -0.71 0.07 -1.08 -0.40
14286 || orf19.341 || || || Putative spermidine export pump; fungal-specific (no human or murine homolog) || 1 0.25 0.38 0.05 0.74 -0.49 -1.48 -0.26 -0.21 0.03 0.19 -0.22 -0.35 -0.20 0.25 -0.78 -0.27
14287 || orf19.2071 || || || Protein of unknown function; induced by alpha pheromone in SpiderM medium || 1 -0.51 0.11 0.22 -0.60 -1.60 -0.01 0.42 0.11 0.45 0.44 -1.03 -0.68 -0.26 -0.78 -0.45
14288 || orf19.7083 || DCC1 || || Protein with a predicted role in sister chromatid cohesion and telomere length maintenance; cell-cycle regulated periodic mRNA expression || 1 -0.41 0.48 -0.05 0.65 -0.46 -1.33 -0.19 0.27 -0.19 0.39 0.62 -0.42 -0.03 -0.08 -0.43 -0.60
14289 || orf19.1901 || MCM3 || || Putative DNA replication protein; periodic mRNA expression, peak at cell-cycle M/G1 phase; Spider biofilm induced || 1 0.21 0.24 0.32 0.58 -0.28 -1.43 -0.09 0.36 -0.20 0.65 0.50 -0.40 0.15 0.08 -0.56 -0.39
14290 || orf19.6155 || || || Ortholog(s) have DNA ligase (ATP) activity and role in DNA ligation, DNA recombination, DNA replication, Okazaki fragment processing, base-excision repair, mitotic cell cycle, nucleotide-excision repair, telomere maintenance || 1 0.15 0.32 0.35 0.34 -0.01 -1.16 -0.00 0.31 -0.12 0.48 0.26 -0.16 0.02 0.25 -0.45
14291 || orf19.2885 || PRI2 || || Putative DNA primase; gene adjacent to and divergently transcribed with CDC68; Hap43-induced; Spider biofilm repressed || 1 -0.15 -0.07 0.41 0.46 -0.27 -1.00 -0.14 0.12 -0.41 0.59 -0.08 -0.26 0.15 0.26 -0.63 -0.82
14292 || orf19.4725 || SWI6 || || Putative component of the MBF and SBF transcription complexes involved in G1/S cell-cycle progression; periodic mRNA expression, peak at cell-cycle G1/S phase || 1 -0.28 -0.05 0.46 0.64 -0.22 -0.65 -0.23 0.30 -0.38 0.50 0.03 -0.05 -0.04 0.19 -0.45 -0.39
14293 || orf19.4367 || SMC1 || || Protein similar to chromosomal ATPases; RNA abundance regulated by tyrosol and cell density; cell-cycle regulated periodic mRNA expression || 1 0.07 -0.15 0.76 0.83 -0.67 -1.24 -0.38 0.23 -0.44 0.64 0.14 -0.60 -0.32 0.08 -0.99 -0.40
14294 || orf19.2216 || PDS5 || || Putative protein with a predicted role in establishment and maintenance of sister chromatid condensation and cohesion; cell-cycle regulated periodic mRNA expression || 1 -0.05 -0.05 0.40 0.28 -0.33 -0.85 0.01 0.38 -0.34 0.42 0.15 -0.19 0.07 -0.04 -0.11 0.01
14295 || orf19.3093 || MSH2 || || Putative DNA mismatch repair factor; transcript regulated by Nrg1; flucytosine repressed; transcript regulated by tyrosol and cell density || 1 0.03 0.05 0.15 0.10 -0.21 -0.80 -0.38 0.14 -0.44 0.36 -0.10 -0.29 0.05 -0.26 -0.38 -0.05
14296 || orf19.3744 || || || Ortholog(s) have tRNA binding activity, role in tRNA export from nucleus and cytoplasm, nuclear pore localization || 1 0.11 0.17 0.14 0.19 -0.35 -0.84 0.01 -0.02 -0.54 0.25 -0.39 -0.19 -0.14 -0.41 -0.57 -0.05
14297 || orf19.3695 || || || Ortholog(s) have diacylglycerol cholinephosphotransferase activity, ethanolaminephosphotransferase activity, role in phosphatidylcholine biosynthetic process, phosphatidylethanolamine biosynthetic process and Golgi apparatus localization || 1 0.21 0.10 0.19 0.10 -0.49 -0.80 -0.30 0.06 -0.50 0.36 -0.26 0.02 -0.23 -0.08 -0.45 -0.77
14298 || orf19.7307 || || || Putative oxidoreductase; similar to S. cerevisiae Pga3p; possible Kex2p substrate || 1 0.32 0.19 0.22 0.63 -1.03 -0.64 -0.48 -0.08 -0.75 0.56 -0.23 -0.53 -0.55 -0.03 -0.57 -0.95
14299 || orf19.7307 || || || Putative oxidoreductase; similar to S. cerevisiae Pga3p; possible Kex2p substrate || 1 0.52 0.48 0.05 0.52 -0.87 -0.79 -0.44 0.13 -0.70 0.37 0.01 -0.81 -0.37 -0.12 -0.63 -1.02
14300 || orf19.7202 || || || Ortholog(s) have role in ER to Golgi vesicle-mediated transport, protein retention in ER lumen, retrograde vesicle-mediated transport, Golgi to ER and COPI-coated vesicle, ER to Golgi transport vesicle, Golgi cisterna localization || 1 0.72 0.37 0.20 0.76 -0.73 -1.24 -0.15 0.96 -0.39 0.36 0.07 -0.02 -0.16 -0.25 -0.21 -1.03
14301 || orf19.3695 || || || Ortholog(s) have diacylglycerol cholinephosphotransferase activity, ethanolaminephosphotransferase activity, role in phosphatidylcholine biosynthetic process, phosphatidylethanolamine biosynthetic process and Golgi apparatus localization || 1 0.68 0.47 0.36 0.91 -0.66 -0.80 -0.55 0.59 -0.19 0.62 0.05 -0.12 -0.05 -0.23 -0.99 -1.05
14302 || orf19.2571 || SEC4 || || Small GTPase of Rab family; role in post-Golgi secretion; possible C-terminal palmitoylation; downregulated on adherence to polystyrene; localizes to the Spitzenkorper during hyphal growth; functional homolog of S. cerevisiae Sec4p || 1 0.37 0.32 0.47 0.60 -0.24 -0.37 -0.16 0.39 -0.03 0.26 -0.04 0.12 -0.03 0.04 -0.30 -0.72
14303 || orf19.3667 || || || Ortholog(s) have microtubule motor activity, protein homodimerization activity and kinesin complex localization || 1 0.26 0.53 0.28 -0.01 -0.08 -1.26 0.37 0.13 0.27 0.31 0.23 0.11 1.34 0.22 -0.76 -0.05
14304 || orf19.433 || || || Ortholog(s) have Rab guanyl-nucleotide exchange factor activity, role in intra-Golgi vesicle-mediated transport, protein complex assembly and TRAPP complex, trans-Golgi network localization || 1 0.08 -0.01 0.27 0.12 -0.25 -0.95 0.44 0.37 0.25 0.19 0.03 0.08 0.39 0.40 -0.29 0.12
14305 || orf19.175 || || || Ortholog of C. dubliniensis CD36 : Cd36_27430, C. parapsilosis CDC317 : CPAR2_802450, Candida tenuis NRRL Y-1498 : CANTEDRAFT_113969 and Debaryomyces hansenii CBS767 : DEHA2A13002g || 1 0.30 0.36 0.08 0.09 0.44 -1.43 0.54 0.61 0.20 0.24 0.40 0.07 0.59 0.38 -0.51 0.17
14306 || orf19.837 || GNA1 || || Glucosamine-6-phosphate acetyltransferase; enzyme of UDP-GlcNAc biosynthesis; required for viability in absence of GlcNAc supplementation; required for persistent infection and wild-type virulence in mouse systemic infection || 1 0.17 0.32 0.16 0.18 -0.08 -0.78 0.17 0.41 0.11 0.19 0.17 0.38 0.31 0.21 -0.58 0.19
14307 || orf19.5054 || || || Putative quinolinate phosphoribosyl transferase, involved in NAD biosynthesis; Hap43p-repressed gene || 1 0.01 0.26 0.08 0.06 0.02 -0.53 0.20 0.38 0.32 -0.08 0.15 0.37 0.36 0.15 -0.27 -0.04
14308 || orf19.5184 || || || Putative Ran guanyl-nucleotide exchange factor; probable signal transducer; Spider biofilm repressed || 1 0.13 0.02 0.03 0.18 -0.32 -0.62 0.16 0.76 0.32 -0.02 0.51 -0.28 0.04 -0.08 -0.21 -0.30
14309 || orf19.4597 || || || Putative F-actin-capping protein subunit beta; possibly an essential gene, disruptants not obtained by UAU1 method || 1 0.10 0.15 -0.11 0.21 -0.29 -0.57 0.23 0.59 0.25 -0.00 0.22 -0.11 0.10 -0.00 -0.39 -0.19
14310 || orf19.5156 || || || Protein similar to S. cerevisiae Phs1p, which is required for growth; has six putative membrane-spanning regions || 1 0.03 -0.14 0.11 0.62 -0.40 -1.05 0.27 1.10 0.44 0.70 0.00 -0.32 -0.01 -0.06 -0.56 -1.02
14311 || orf19.4931 || || || Putative tRNA-Cys synthetase; induced by alpha pheromone in SpiderM medium; ribosomal subunits, translation factors, tRNA synthetases are downregulated upon phagocytosis by murine macrophage || 1 -0.36 -0.06 -0.27 -0.02 -0.31 -0.72 0.26 0.17 0.61 0.48 0.18 0.15 0.02 -0.05 -0.29 -0.09
14312 || orf19.4606 || ERG8 || || Putative phosphomevalonate kinase; enzyme of the mevalonate pathway of isoprenoid biosynthesis; transcript regulated by Nrg1; possible drug target; not conserved in H. sapiens || 1 -0.25 0.02 0.08 0.06 -0.41 -1.03 0.28 0.46 0.57 0.40 0.13 0.01 0.21 0.09 0.16 0.18
14313 || orf19.6569 || || || Predicted transmembrane transporter; induced during chlamydospore formation in both C. albicans and C. dubliniensis || 1 0.03 0.18 0.41 -0.29 -0.69 -1.34 0.39 0.11 0.71 1.00 0.02 -0.05 0.12 -0.07 0.05 -0.70
14314 || orf19.4105 || || || Ortholog(s) have role in DNA repair, DNA replication checkpoint, establishment of mitotic sister chromatid cohesion, maintenance of DNA repeat elements, meiotic chromosome segregation, replication fork arrest, replication fork protection || 1 -0.20 0.28 0.49 0.11 -0.57 -1.34 0.17 0.32 0.23 1.30 0.24 -0.12 0.13 0.03 -0.43 -0.45
14315 || orf19.7631 || SLD5 || || Putative GINS complex subunit; cell-cycle regulated periodic mRNA expression || 1 -0.14 0.12 0.46 -0.04 -0.17 -0.75 0.47 0.41 0.25 0.58 0.09 0.07 0.28 -0.33 -0.32 -0.05
14316 || orf19.5933 || || || Protein of unknown function; transcript induced by benomyl treatment || 1 0.50 0.34 0.45 -0.29 -0.83 -0.58 1.13 0.49 0.30 0.52 -1.16 -0.69 0.82 1.60 -1.11 -0.65
14317 || orf19.6958 || ECM18 || || Ortholog(s) have mitochondrion localization || 1 0.05 0.10 0.77 0.29 -0.41 -0.98 0.76 0.52 0.29 0.17 -0.69 -0.69 0.49 0.83 -0.38 -0.39
14318 || orf19.6698 || || || Ortholog(s) have asparagine-tRNA ligase activity, role in mitochondrial asparaginyl-tRNA aminoacylation and mitochondrion localization || 1 0.46 -0.03 0.33 -0.14 -0.78 -1.04 1.13 0.89 0.73 0.61 -0.51 -0.82 0.36 0.69 -0.33 -0.83
14319 || orf19.2785 || ATP7 || || Putative subunit of the F1F0-ATPase complex; colony morphology-related gene regulation by Ssn6; farnesol, macrophage-downregulated protein abundance; protein present in exponential and stationary yeast growth phases; Hap43-induced || 1 0.49 0.46 0.05 0.25 -0.64 -0.78 0.62 0.81 0.22 0.26 -0.17 -0.58 0.34 0.89 -0.38 -0.38
14320 || orf19.3631 || STN1 || || Protein involved in telomere maintenance; forms a complex with Ten1p || 1 0.93 0.92 0.06 0.05 -0.25 -1.07 0.49 0.28 0.50 0.14 -0.33 -0.57 0.76 0.74 -0.78 -0.54
14321 || orf19.938 || || || Ortholog of C. dubliniensis CD36 : Cd36_50520, C. parapsilosis CDC317 : CPAR2_304000, Candida tenuis NRRL Y-1498 : cten_CGOB_00233 and Debaryomyces hansenii CBS767 : DEHA2E12408g || 1 1.05 0.84 -0.06 0.56 -1.48 -1.98 1.27 0.31 1.24 0.72 -0.88 -0.00 2.10 1.41 -1.84 -0.62
14322 || orf19.3767 || PEP1 || || Type I transmembrane sorting receptor for multiple vacuolar hydrolases; cycles between late-Golgi and prevacuolar endosome-like compartments; rat catheter biofilm repressed || 1 -0.07 -0.01 0.28 0.09 -0.56 -0.65 0.18 0.02 0.14 -0.09 -0.53 -0.44 0.71 0.35 -0.45 -0.11
14323 || orf19.100 || || || Alpha/beta hydrolase and lipase domain protein; Hap43-repressed; Spider and flow model biofilm induced || 1 0.19 0.16 0.22 0.84 -1.23 -3.28 0.32 0.25 1.06 0.19 -2.31 -1.28 1.52 0.84 -1.12 -1.27
14324 || orf19.310 || || || Putative mitochondrial protein with a predicted role in cell wall biogenesis; possibly an essential gene, disruptants not obtained by UAU1 method || 1 0.00 0.00 0.12 0.70 -0.87 -1.21 0.29 0.09 0.30 0.26 -0.79 -0.95 0.30 0.63 -0.52 -0.09
14325 || orf19.1377 || IPK2 || || Putative inositol polyphosphate multikinase; moderately induced at 42 deg || 1 0.45 0.48 0.01 0.35 -0.91 -0.93 0.60 0.17 0.12 0.36 -0.20 -0.57 0.32 0.55 -0.16 -0.16
14326 || orf19.5069 || || || Ortholog of S. cerevisiae Sae3; meiosis specific protein involved in DMC1-dependent meiotic recombination in S. cerevisiae; Spider biofilm induced || 1 -0.04 0.10 -0.61 0.30 -2.34 -3.07 0.89 0.12 0.15 0.44 0.13 -1.09 0.23 0.59 -0.56 -0.79
14327 || orf19.5069 || || || Ortholog of S. cerevisiae Sae3; meiosis specific protein involved in DMC1-dependent meiotic recombination in S. cerevisiae; Spider biofilm induced || 1 0.38 0.19 -0.21 0.46 -2.11 -3.03 0.89 -0.09 0.17 0.60 -0.08 -1.29 0.25 0.29 -0.57 -0.87
14328 || orf19.5069 || || || Ortholog of S. cerevisiae Sae3; meiosis specific protein involved in DMC1-dependent meiotic recombination in S. cerevisiae; Spider biofilm induced || 1 0.28 0.33 -0.32 0.46 -2.27 -4.16 1.09 0.21 0.47 0.69 0.22 -1.31 0.63 0.60 -0.71 -0.90
14329 || orf19.5069 || || || Ortholog of S. cerevisiae Sae3; meiosis specific protein involved in DMC1-dependent meiotic recombination in S. cerevisiae; Spider biofilm induced || 1 0.29 0.37 -0.30 0.39 -1.11 -2.80 0.88 -0.03 0.43 0.52 0.39 -0.56 0.63 0.71 -0.37 -0.58
14330 || orf19.5069 || || || Ortholog of S. cerevisiae Sae3; meiosis specific protein involved in DMC1-dependent meiotic recombination in S. cerevisiae; Spider biofilm induced || 1 0.74 0.74 -0.20 0.50 -0.80 -2.93 0.61 0.10 0.43 0.42 0.30 -0.97 0.78 0.87 -0.26 -0.63
14331 || orf19.4069 || || || Protein of unknown function; repressed by alpha pheromone in SpiderM medium || 1 0.11 0.53 0.44 -0.27 -1.62 -3.36 -0.13 0.50 0.62 0.97 -0.36 -0.61 1.01 0.97 -0.41 -0.54
14332 || orf19.6958 || ECM18 || || Ortholog(s) have mitochondrion localization || 1 0.58 0.13 0.43 0.99 -0.94 -1.79 0.42 0.87 0.62 0.41 -0.23 -0.81 0.58 0.65 -0.26 0.01
14333 || orf19.6321 || PGA48 || || Putative GPI-anchored adhesin-like protein; similar to S. cerevisiae Spi1p, which is induced at stationary phase; transcript induced in high iron; flow model biofilm induced; Spider biofilm repressed || 1 0.17 0.13 0.39 0.21 -0.35 -1.00 -0.03 0.33 0.20 0.07 -0.01 -0.06 0.21 0.44 -0.31 -0.01
14334 || orf19.6321 || PGA48 || || Putative GPI-anchored adhesin-like protein; similar to S. cerevisiae Spi1p, which is induced at stationary phase; transcript induced in high iron; flow model biofilm induced; Spider biofilm repressed || 1 0.16 0.23 0.33 0.22 -0.67 -1.30 0.00 0.52 0.01 -0.04 0.10 -0.06 0.41 0.68 -0.45 -0.01
14335 || orf19.6321 || PGA48 || || Putative GPI-anchored adhesin-like protein; similar to S. cerevisiae Spi1p, which is induced at stationary phase; transcript induced in high iron; flow model biofilm induced; Spider biofilm repressed || 1 0.15 0.14 0.19 0.11 -0.52 -1.05 0.05 0.46 -0.01 -0.07 0.06 -0.02 0.20 0.31 -0.40 -0.05
14336 || orf19.6321 || PGA48 || || Putative GPI-anchored adhesin-like protein; similar to S. cerevisiae Spi1p, which is induced at stationary phase; transcript induced in high iron; flow model biofilm induced; Spider biofilm repressed || 1 0.14 0.22 0.24 0.20 -0.61 -1.09 0.05 0.49 0.09 -0.05 0.10 -0.04 0.27 0.23 -0.49 -0.03
14337 || orf19.6321 || PGA48 || || Putative GPI-anchored adhesin-like protein; similar to S. cerevisiae Spi1p, which is induced at stationary phase; transcript induced in high iron; flow model biofilm induced; Spider biofilm repressed || 1 0.16 0.19 0.29 0.10 -0.72 -1.44 0.00 0.52 0.08 -0.24 0.12 -0.32 0.38 0.47 -0.63 -0.23
14338 || orf19.2238 || LTE1 || || Protein similar to GDP/GTP exchange factors; repressed by alpha pheromone in SpiderM medium; flow model biofilm repressed || 1 0.14 0.27 -0.08 0.04 -1.08 -1.95 0.39 0.75 0.31 0.46 0.33 0.15 0.85 0.92 -0.98 0.04
14339 || orf19.2837 || ALG5 || || Putative glucosyltransferase involved in cell wall mannan biosynthesis; possibly an essential gene, disruptants not obtained by UAU1 method || 1 0.31 0.25 0.62 0.48 -1.97 -1.81 0.20 0.52 0.52 0.75 -0.11 -0.35 0.94 0.27 -1.46 -0.57
14340 || orf19.2837 || ALG5 || || Putative glucosyltransferase involved in cell wall mannan biosynthesis; possibly an essential gene, disruptants not obtained by UAU1 method || 1 -0.02 -0.14 0.02 -0.09 -1.72 -2.26 0.16 0.45 0.36 0.62 -0.17 -0.10 0.87 0.35 -1.47 -0.43
14341 || orf19.1510 || SRD1 || || Sur7 family protein with PalI-like domains; not required for stress responses; mutant is viable || 1 0.19 0.31 0.12 0.42 -1.87 -2.09 0.37 0.12 0.05 0.16 -0.63 -0.40 0.61 0.51 -1.21 -0.46
14342 || orf19.1510 || SRD1 || || Sur7 family protein with PalI-like domains; not required for stress responses; mutant is viable || 1 0.31 0.33 0.38 0.42 -1.14 -1.75 0.25 0.24 0.04 0.41 -0.47 -0.07 0.77 0.75 -0.89 -0.07
14343 || orf19.5393 || || || Putative cysteine sulfinate decarboxylase; transcript positively regulated by Tbf1; Spider biofilm induced || 1 0.37 -0.17 0.25 0.71 -1.34 -1.45 0.67 0.39 0.10 0.45 -0.27 -0.34 0.70 0.81 -1.06 -0.29
14344 || orf19.6318 || || || Ortholog(s) have endoplasmic reticulum, mitochondrion localization || 1 0.21 0.14 0.06 0.20 -0.78 -1.12 0.43 0.50 -0.08 0.04 -0.20 -0.38 0.43 0.44 -0.58 -0.34
14345 || orf19.5139 || || || Ortholog of C. dubliniensis CD36 : Cd36_72800, Candida tropicalis MYA-3404 : CTRG_05211 and Candida albicans WO-1 : CAWG_05649 || 1 0.55 0.07 0.46 0.17 -0.88 -1.22 0.27 0.36 0.29 0.19 -0.50 -0.53 0.20 0.32 -0.80 -0.23
14346 || orf19.804 || || || Putative mitochondrial carrier family transporter; rat catheter biofilm induced || 1 0.40 0.53 0.51 0.67 -1.60 -1.66 0.34 0.82 0.79 0.98 -1.10 -0.78 0.38 0.81 -1.43 -1.00
14347 || orf19.1392 || || || Ortholog(s) have chaperone binding, protein disulfide isomerase activity, unfolded protein binding activity and role in ER-associated ubiquitin-dependent protein catabolic process, protein retention in ER lumen || 1 0.33 0.26 0.22 0.45 -0.64 -1.12 0.37 0.60 0.30 0.17 -0.64 -0.38 0.30 0.21 -0.39 -0.54
14348 || orf19.938 || || || Ortholog of C. dubliniensis CD36 : Cd36_50520, C. parapsilosis CDC317 : CPAR2_304000, Candida tenuis NRRL Y-1498 : cten_CGOB_00233 and Debaryomyces hansenii CBS767 : DEHA2E12408g || 1 0.33 0.57 0.14 0.65 -1.89 -3.93 1.19 0.68 0.80 0.67 -0.96 -1.65 2.27 2.00 -1.33 -1.79
14349 || orf19.1392 || || || Ortholog(s) have chaperone binding, protein disulfide isomerase activity, unfolded protein binding activity and role in ER-associated ubiquitin-dependent protein catabolic process, protein retention in ER lumen || 1 0.27 0.46 0.01 -0.07 -1.13 -1.72 0.69 0.69 0.44 0.44 -0.53 -0.79 0.68 0.51 -0.75 -0.77
14350 || orf19.1888 || || || Putative nicotinamide riboside hydrolase; cleaves N-glycosidic bonds in nucleosides; pyrimidine salvage and nicotinamide riboside salvage pathways; Spider biofilm induced || 1 0.52 0.44 0.36 0.28 -1.00 -1.75 0.71 0.88 1.08 0.84 -0.34 -0.53 0.27 0.31 -1.00 -0.33
14351 || orf19.7301 || || || Has domain(s) with predicted DNA binding activity || 1 0.50 0.38 0.07 0.30 -1.65 -2.84 1.21 0.95 1.01 0.82 -0.04 -0.55 0.49 0.85 -1.58 -0.83
14352 || orf19.7301 || || || Has domain(s) with predicted DNA binding activity || 1 -0.05 0.39 0.25 0.42 -0.57 -2.11 0.84 0.84 0.97 1.01 -0.11 -0.46 0.49 0.88 -0.73 -0.68
14353 || orf19.7301 || || || Has domain(s) with predicted DNA binding activity || 1 0.78 1.07 0.38 0.16 -0.93 -1.96 0.68 0.74 1.02 1.02 -0.04 -0.48 0.67 1.26 -0.62 -0.61
14354 || orf19.3782.2 || || || Ortholog(s) have role in cristae formation and integral to mitochondrial inner membrane, mitochondrial crista junction localization || 1 0.25 0.29 0.21 0.43 -0.67 -0.72 0.46 0.75 0.49 0.19 0.01 -0.10 0.21 0.52 -0.40 -0.51
14355 || orf19.1562 || || || Protein of unknown function; flow model biofilm induced; Spider biofilm induced; repressed by alpha pheromone in SpiderM medium || 1 1.20 1.29 0.87 1.37 -2.20 -2.69 1.38 1.29 0.68 0.60 0.04 -0.87 1.19 1.40 -1.25 -1.00
14356 || orf19.1562 || || || Protein of unknown function; flow model biofilm induced; Spider biofilm induced; repressed by alpha pheromone in SpiderM medium || 1 1.25 1.34 0.88 1.67 -2.08 -2.54 1.20 1.19 0.38 0.30 0.04 -1.03 1.05 0.90 -1.24 -1.09
14357 || orf19.433 || || || Ortholog(s) have Rab guanyl-nucleotide exchange factor activity, role in intra-Golgi vesicle-mediated transport, protein complex assembly and TRAPP complex, trans-Golgi network localization || 1 0.24 0.12 0.27 0.31 -0.51 -0.92 0.16 0.55 0.28 0.37 0.21 -0.26 0.29 0.09 -0.36 -0.55
14358 || orf19.5266 || || || Planktonic growth-induced gene || 1 0.27 0.34 -0.11 -0.01 -0.66 -1.43 -0.06 0.05 0.16 0.20 -0.28 -0.03 0.41 -0.00 -0.63 -0.06
14359 || orf19.5762 || PGA61 || || Putative GPI-anchored protein || 1 0.88 0.65 -0.71 -0.08 -1.01 -2.58 -0.25 0.00 -0.57 0.09 -0.65 -0.23 0.15 0.74 -0.84 -0.10
14360 || orf19.69.2 || || || Dubious open reading frame || 1 0.67 0.85 -0.05 -0.09 -1.08 -3.82 0.60 0.57 -0.42 0.50 -0.82 -0.58 0.51 1.84 -0.81 0.97
14361 || orf19.1254 || SEC23 || || Putative GTPase-activating protein; regulated upon yeast-hypha switch; Spider biofilm repressed || 1 0.18 0.14 0.15 0.33 -0.28 -0.87 0.02 0.23 0.07 0.22 -0.00 -0.11 -0.08 0.29 -0.31 0.30
14362 || orf19.4236 || RET2 || || Delta subunit of the coatomer complex (COPI); coats Golgi-derived transport vesicles; involved in retrograde transport between Golgi and ER; interacts with Crk1 in the two-hybrid system; Spider biofilm repressed || 1 0.10 -0.06 -0.10 0.05 -0.71 -0.96 0.16 0.51 -0.13 0.38 0.41 0.21 -0.30 -0.41 -0.41 0.62
14363 || orf19.316 || SEC13 || || Putative protein transport factor; antigenic during murine systemic infection; macrophage-downregulated protein; protein level decreases in stationary phase cultures; Spider biofilm repressed || 1 0.20 0.21 0.18 0.26 -0.84 -0.82 0.04 0.45 -0.21 0.14 0.44 0.09 -0.51 -0.06 -0.42 0.42
14364 || orf19.4090.1 || || || Ortholog(s) have role in vacuolar proton-transporting V-type ATPase complex assembly and endoplasmic reticulum membrane localization || 1 0.09 -0.04 0.15 0.49 -1.02 -1.05 0.31 0.93 -0.05 0.57 0.30 -0.00 -0.20 -0.19 -0.66 0.12
14365 || orf19.3083 || || || Putative lipid phosphatase of the endoplasmic reticulum; role in DNA repair, actin cytoskeleton organization, cellular manganese ion homeostasis; Spider biofilm repressed || 1 -0.33 -0.03 0.11 0.50 -0.45 -1.32 0.20 0.53 0.10 0.53 0.38 0.21 -0.30 0.16 -0.08 0.29
14366 || orf19.3083 || || || Putative lipid phosphatase of the endoplasmic reticulum; role in DNA repair, actin cytoskeleton organization, cellular manganese ion homeostasis; Spider biofilm repressed || 1 -0.57 -0.46 -0.04 0.29 -0.76 -1.45 -0.08 0.66 -0.17 0.26 0.57 -0.19 -0.19 0.29 -0.16 0.57
14367 || orf19.612 || || || Ortholog of S. cerevisiae : AIM32, C. glabrata CBS138 : CAGL0L01529g, C. dubliniensis CD36 : Cd36_33550, C. parapsilosis CDC317 : CPAR2_702070 and Candida tenuis NRRL Y-1498 : CANTEDRAFT_114174 || 1 0.03 -0.07 -0.30 0.12 -0.84 -1.38 0.09 0.56 -0.09 0.22 0.15 -0.57 -0.21 -0.05 -0.34 0.49
14368 || orf19.5664 || HOF1 || || Ortholog of S. cerevisiae Hof1; a protein localized to the bud neck and required for cytokinesis in S. cerevisiae; periodic mRNA expression, peak at cell-cycle G2/M phase; mutant is viable || 1 -0.12 0.05 -0.63 -0.14 -0.97 -1.63 0.28 0.65 0.08 0.03 0.41 -0.05 -0.07 0.21 -0.49 0.58
14369 || orf19.5563 || RNH1 || || Ribonuclease H (RNAse H); hyphal-induced; flucytosine induced; similar to orf19.5564 (see Locus History); possibly essential (UAU1 method); rat catheter biofilm induced; flow model biofilm repressed || 1 -0.12 -0.22 -0.28 0.17 -0.72 -0.88 0.47 0.76 -0.04 0.60 -0.01 0.14 -0.11 0.25 -0.17 0.04
14370 || orf19.6929 || || || Ortholog(s) have acid phosphatase activity and cytosol, nucleus localization || 1 -0.05 -0.08 -0.38 0.06 -0.95 -1.09 0.74 0.63 0.11 0.71 0.30 0.05 -0.08 0.22 -0.73 0.26
14371 || orf19.3086 || SEC10 || || Ortholog(s) have role in Golgi to plasma membrane transport, cytokinetic cell separation, exocytosis and cell cortex of cell tip, cell division site, cytosol, exocyst, mating projection tip, mitotic spindle pole body, nucleus localization || 1 -0.08 -0.10 0.08 -0.21 -0.47 -0.90 0.29 0.26 0.14 0.25 0.19 0.04 0.00 0.23 -0.09 0.22
14372 || orf19.3289 || || || Phosphorylated protein of unknown function || 1 0.10 -0.13 -0.17 -0.42 -0.55 -1.27 0.10 0.64 0.20 0.13 0.29 0.12 0.29 0.58 -0.04 0.16
14373 || orf19.3264 || CCE1 || || Putative Holliday junction resolving enzyme; similar to S. cerevisiae Cce1p || 1 0.02 -0.41 -0.44 -0.00 -0.69 -1.32 0.20 0.59 -0.04 0.24 0.61 0.37 0.02 0.62 0.20 0.63
14374 || orf19.4228 || || || Protein with a role in insertion of tail-anchored proteins into the ER membrane; Spider biofilm repressed || 1 0.02 -0.06 -0.29 -0.19 -0.26 -0.48 0.11 0.31 0.07 0.26 0.14 0.38 -0.10 0.40 -0.17 0.31
14375 || orf19.2347 || MNN2 || || Alpha-1,2-mannosyltransferase; similar to S. cerevisiae Mnn2; role in cell wall integrity, temperature sensitivity; iron utilization in low iron; Tn mutation affects filamentous growth; filament induced; increased chitin exposes beta-glucan || 1 0.07 -0.04 -0.72 -0.54 -0.62 -1.23 0.41 1.10 0.10 0.60 0.56 0.01 -0.53 0.66 -0.57 0.61
14376 || orf19.2775 || IDI1 || || Ortholog(s) have isopentenyl-diphosphate delta-isomerase activity, role in farnesyl diphosphate biosynthetic process and cytosol, nucleus localization || 1 -0.13 -0.12 -0.71 -0.30 -0.96 -1.77 0.17 0.65 -0.25 0.78 0.80 0.26 -0.45 0.74 -0.26 0.18
14377 || orf19.331 || || || Ortholog(s) have S-adenosylmethionine-dependent methyltransferase activity, protein methyltransferase activity and role in peptidyl-glutamine methylation, regulation of translation || 1 -0.13 -0.19 -0.28 -0.26 -0.39 -0.63 0.11 0.39 0.13 0.34 0.23 0.24 -0.47 0.33 0.04 0.09
14378 || orf19.3744 || || || Ortholog(s) have tRNA binding activity, role in tRNA export from nucleus and cytoplasm, nuclear pore localization || 1 0.09 0.21 -0.17 -0.30 -0.11 -0.79 0.10 0.23 0.05 0.65 0.14 -0.01 0.02 0.19 -0.22 0.18
14379 || orf19.6579 || || || Ortholog of C. dubliniensis CD36 : Cd36_71340, C. parapsilosis CDC317 : CPAR2_301350, Candida tenuis NRRL Y-1498 : CANTEDRAFT_114098 and Debaryomyces hansenii CBS767 : DEHA2D03432g || 1 -0.26 0.27 -0.79 -0.80 -0.98 -2.39 0.61 0.74 0.59 1.55 0.38 -0.12 0.41 -0.05 -0.70 0.00
14380 || orf19.3920 || || || Ortholog(s) have protein disulfide isomerase activity, protein disulfide oxidoreductase activity, role in protein folding and fungal-type vacuole localization || 1 -0.18 -0.14 -0.40 0.30 -0.63 -1.52 0.46 1.25 0.31 0.73 0.76 0.22 -0.18 -0.08 0.13 -0.70
14381 || orf19.3350 || MRP20 || || Component of mitochondrial ribosome; decreased expression in hyphae compared to yeast-form cells || 1 -0.11 0.01 -0.35 -0.13 -0.45 -0.66 0.17 0.19 0.02 0.38 0.22 0.37 0.03 -0.15 -0.02 -0.25
14382 || orf19.2930 || || || Predicted translation initiation factor; role in translational initiation; Spider biofilm repressed || 1 -0.38 0.13 -0.50 -0.02 -0.76 -1.38 0.23 0.67 -0.15 0.60 0.64 0.22 -0.30 -0.51 -0.33 -0.27
14383 || orf19.6526 || || || Ortholog(s) have COPI-coated vesicle, Golgi apparatus localization || 1 -0.34 -0.33 -0.34 0.26 -1.13 -1.82 0.18 0.84 0.13 0.69 -0.00 0.25 0.25 -0.39 -0.57 -0.07
14384 || orf19.4109 || PMT4 || || Protein mannosyltransferase; required for WT cell wall composition and virulence in mice; roles in hyphal growth and drug sensitivity; one of 5 family members; Axl2 a substrate; Spider biofilm repressed; Bcr1-repressed in RPMI a/a biofilm || 1 -0.33 -0.25 -0.04 0.14 -0.62 -1.28 0.25 0.72 0.18 0.30 0.67 0.31 0.17 -0.22 -0.58 -0.26
14385 || orf19.3225 || CWH43 || || Putative sensor/transporter protein with a predicted role in cell wall biogenesis; possibly an essential gene, disruptants not obtained by UAU1 method; flow model and rat catheter biofilm repressed || 1 -0.23 -0.22 -0.24 0.19 -0.68 -1.76 0.46 0.87 0.12 0.15 0.43 -0.20 0.06 -0.12 -0.53 -0.45
14386 || orf19.2478 || || || Ortholog of C. dubliniensis CD36 : Cd36_05410, C. parapsilosis CDC317 : CPAR2_107480, Candida tenuis NRRL Y-1498 : CANTEDRAFT_94695 and Debaryomyces hansenii CBS767 : DEHA2D02288g || 1 -0.53 -0.12 -0.68 -0.44 -0.81 -2.11 0.69 0.89 0.23 0.56 0.69 -0.31 0.58 -0.11 -0.91 -0.58
14387 || orf19.4890 || CLA4 || || Ste20p family Ser/Thr kinase required for wild-type filamentous growth, organ colonization and virulence in mouse systemic infection; role in chlamydospore formation; functional homolog of S. cerevisiae Cla4p; mutant caspofungin sensitive || 1 0.12 -0.09 -0.36 -0.09 -0.52 -1.21 0.09 0.35 -0.14 0.64 -0.01 -0.13 0.35 0.17 -0.20 -0.35
14388 || orf19.7190 || OGG1 || || Mitochondrial glycosylase/lyase; repairs oxidative damage to mitochondrial DNA, contributes to UVA resistance, role in base-excision repair; Spider biofilm induced || 1 -0.00 -0.21 -0.29 -0.02 -0.90 -3.08 0.02 1.82 -0.41 0.26 0.28 -0.79 -1.65
14389 || orf19.1825 || || || Protein of unknown function; mutants are viable; filament induced; regulated by Nrg1, Rfg1, Tup1 || 1 0.23 0.34 -0.19 -0.12 -0.39 -1.80 -0.14 0.86 0.37 1.23 0.08 -0.06 -0.03 0.33 -0.58 -0.50
14390 || orf19.30 || SPF1 || || P-type calcium-transporting ATPase, involved in control of calcium homeostasis, response to ER stress, hyphal growth, biofilm formation and virulence || 1 0.16 0.02 -0.21 0.23 -0.47 -1.20 0.20 0.76 0.42 0.79 0.42 -0.25 -0.16 0.32 -0.25 -0.28
14391 || orf19.7425 || || || Ortholog(s) have uracil DNA N-glycosylase activity, role in DNA repair and mitochondrion, nucleus localization || 1 -0.01 -0.05 -0.09 0.12 -0.72 -1.89 0.21 0.70 0.54 0.75 0.08 -0.65 -0.04 0.18 -0.69 -0.85
14392 || orf19.6699 || || || Ortholog(s) have histidinol-phosphatase activity, role in histidine biosynthetic process and cytosol, nucleus localization || 1 0.06 0.03 -0.05 0.04 -0.68 -1.51 0.41 0.56 0.68 0.40 -0.19 -0.42 -0.27 0.39 -0.52 -0.80
14393 || orf19.4376 || || || Protein of unknown function; Spider biofilm induced || 1 0.20 -0.11 -0.47 -0.94 -1.70 -2.48 0.41 0.69 0.34 0.55 0.17 -0.28 -0.37 0.34 -0.77 -1.23
14394 || orf19.7489 || || || Ortholog(s) have Rho GTPase activator activity || 1 -0.09 0.10 -0.33 -0.17 -0.77 -1.35 0.17 0.47 -0.02 0.49 -0.29 -0.89 -0.34 0.05 -0.85 -0.93
14395 || orf19.3558 || || || Ortholog(s) have Golgi apparatus, endoplasmic reticulum localization || 1 -0.17 0.03 -0.31 -0.00 -0.23 -1.57 -0.06 0.43 -0.26 0.04 0.35 -0.17 -0.03 0.16 -0.57 -0.29
14396 || orf19.7588 || || || Ortholog(s) have mitochondrion localization || 1 0.25 0.15 -0.20 0.26 -0.13 -1.77 0.94 0.96 0.08 0.26 1.05 0.35 0.14 0.25 -1.05 0.30
14397 || orf19.1309 || || || Ortholog of C. dubliniensis CD36 : Cd36_43290, C. parapsilosis CDC317 : CPAR2_403630, Candida tenuis NRRL Y-1498 : CANTEDRAFT_114295 and Debaryomyces hansenii CBS767 : DEHA2G17336g || 1 0.36 0.05 -0.50 0.28 -0.35 -2.71 0.62 1.22 -0.38 0.77 0.64 0.19 0.38 0.26 -1.11 0.27
14398 || orf19.2328 || || || Ortholog of C. dubliniensis CD36 : Cd36_10220, C. parapsilosis CDC317 : CPAR2_210530, Candida tenuis NRRL Y-1498 : CANTEDRAFT_105553 and Debaryomyces hansenii CBS767 : DEHA2G14432g || 1 0.16 0.10 -0.25 -0.40 -0.69 -1.28 0.09 0.63 -0.24 0.07 0.54 0.07 -0.07 0.28 -0.19 0.21
14399 || orf19.7035 || RFC2 || || Putative heteropentameric replication factor C subunit; periodic mRNA expression, peak at cell-cycle G1/S phase || 1 0.57 0.78 -0.33 -0.31 -0.81 -2.60 0.40 1.14 -0.18 0.48 1.11 0.34 -0.11 0.52 -0.03 0.45
14400 || orf19.1309 || || || Ortholog of C. dubliniensis CD36 : Cd36_43290, C. parapsilosis CDC317 : CPAR2_403630, Candida tenuis NRRL Y-1498 : CANTEDRAFT_114295 and Debaryomyces hansenii CBS767 : DEHA2G17336g || 1 0.30 0.10 -0.46 0.21 -0.60 -2.14 0.42 0.93 0.08 0.66 0.84 -0.14 -0.08 0.87 -0.26 0.44
14401 || orf19.4090.1 || || || Ortholog(s) have role in vacuolar proton-transporting V-type ATPase complex assembly and endoplasmic reticulum membrane localization || 1 0.08 0.25 -0.27 0.03 -0.53 -1.31 0.47 1.11 -0.25 0.62 0.77 0.35 -0.06 0.08 -0.19 0.13
14402 || orf19.731 || EMP46 || || Protein similar to S. cerevisiae Emp46, an integral membrane component of ER-derived COPII-coated vesicles; functions in ER to Golgi transport; induced by alpha pheromone in SpiderM medium || 1 0.37 0.11 -0.59 -0.06 -0.54 -1.28 0.60 1.05 0.17 0.40 0.60 0.05 0.09 -0.16 -0.34 -0.01
14403 || orf19.1202 || || || Ortholog of C. dubliniensis CD36 : Cd36_60350, C. parapsilosis CDC317 : CPAR2_603550, Candida tenuis NRRL Y-1498 : CANTEDRAFT_114325 and Debaryomyces hansenii CBS767 : DEHA2G04950g || 1 0.37 0.63 -0.09 0.37 -1.01 -1.51 0.70 0.63 -0.26 0.03 0.70 -0.25 0.26 0.24 -0.89 0.00
14404 || orf19.2416.1 || MLC1 || || Microtubule-dependent localized protein; at Spitzenkorper and cytokinetic ring in hyphae; cell-cycle dependent localization to tip polarisome, bud neck in yeast and pseudohyphae; sumoylation target; rat catheter, Spider biofilm repressed || 1 0.69 0.79 -0.17 -0.09 -2.12 -2.54 1.16 1.68 0.14 0.44 1.20 0.05 0.44 0.75 -1.38 -0.13
14405 || orf19.548 || CDC10 || || Septin, required for wild-type cell, hyphal, or chlamydospore morphology; role in virulence and kidney tissue invasion in mouse infection; forms ring at sites of cell division and filaments in mature chlamydospore; Spider biofilm repressed || 1 0.44 0.36 -0.37 -0.03 -0.90 -1.78 0.44 0.86 -0.15 0.50 0.74 -0.11 0.22 0.29 -0.73 0.03
14406 || orf19.2885 || PRI2 || || Putative DNA primase; gene adjacent to and divergently transcribed with CDC68; Hap43-induced; Spider biofilm repressed || 1 0.40 0.19 0.00 0.91 -0.61 -2.31 0.25 1.55 -0.20 1.00 1.18 0.05 0.61 0.09 -0.76 -0.29
14407 || orf19.262 || SMC3 || || Protein similar to S. cerevisiae Smc3p, which is an ATPase involved in sister chromatid cohesion; likely to be essential for growth, based on an insertional mutagenesis strategy || 1 0.97 0.94 -0.25 0.89 -1.02 -2.94 0.93 1.33 -0.41 1.49 1.50 0.46 0.64 -0.72 -0.08
14408 || orf19.4105 || || || Ortholog(s) have role in DNA repair, DNA replication checkpoint, establishment of mitotic sister chromatid cohesion, maintenance of DNA repeat elements, meiotic chromosome segregation, replication fork arrest, replication fork protection || 1 0.40 0.57 -0.04 0.45 -1.15 -2.14 0.81 1.04 -0.15 1.37 0.91 -0.08 0.35 0.30 -0.34 -0.18
14409 || orf19.7232 || IRR1 || || Putative cohesin complex subunit; cell-cycle regulated periodic mRNA expression || 1 0.07 0.12 -0.10 0.18 -1.24 -1.94 0.36 0.92 -0.07 1.05 1.12 0.25 0.23 0.93 -0.54 0.30
14410 || orf19.7394 || GDA1 || || Golgi membrane GDPase, required for wild-type O-mannosylation, not N-glycosylation; required for wild-type hyphal induction, cell wall, and cell surface charge; not required for HeLa cell adherence; functional homolog of S. cerevisiae Gda1p || 1 -0.03 0.06 -0.02 0.41 -1.37 -1.68 0.31 0.80 -0.07 0.91 0.59 0.03 0.39 0.49 -0.39 -0.20
14411 || orf19.5839 || PDR17 || || Fungal-specific protein (no human or murine homolog); role in sensitivity to fluconazole, specifically || 1 0.02 -0.17 0.00 0.34 -0.80 -0.86 0.26 0.47 -0.15 0.65 0.40 -0.01 0.25 0.37 -0.53 -0.38
14412 || orf19.2796 || || || Ortholog(s) have DNA-directed DNA polymerase activity, role in DNA replication initiation, telomere capping and alpha DNA polymerase:primase complex, cytosol, nuclear envelope localization || 1 0.36 0.14 0.03 0.20 -0.55 -1.53 0.09 0.60 -0.16 0.64 0.64 -0.01 -0.20 0.32 -0.49 -0.22
14413 || orf19.7409 || ERV25 || || Component of COPII-coated vesicles; transcript induced upon filamentous growth; rat catheter biofilm repressed || 1 0.32 0.28 0.20 -0.62 -1.59 0.23 0.44 -0.07 0.34 0.24 0.09 -0.22 0.49 -0.58 -0.27
14414 || orf19.5182 || POL3 || || Large subunit of DNA polymerase III; partially complements defects of an S. cerevisiae cdc2 mutant; differing reports about periodic (G1/S) or non-periodic mRNA expression through cell cycle; Hap43p-repressed || 1 0.33 0.35 0.17 0.03 -0.44 -1.02 -0.08 0.51 -0.16 0.36 0.31 -0.07 -0.40 0.28 -0.73 -0.04
14415 || orf19.3001 || TEM1 || || Protein similar to S. cerevisiae Tem1p, which is a GTPase involved in termination of the M phase of the cell cycle; induced under Cdc5p depletion || 1 0.62 0.50 0.36 0.68 -1.70 -1.61 -0.07 0.49 -0.07 0.75 0.28 0.08 -0.01 0.75 -0.41 0.50
14416 || orf19.3001 || TEM1 || || Protein similar to S. cerevisiae Tem1p, which is a GTPase involved in termination of the M phase of the cell cycle; induced under Cdc5p depletion || 1 1.12 0.67 0.83 0.95 -1.12 -1.53 0.32 0.76 -0.26 0.41 0.32 0.06 0.43 0.44 -0.35 0.31
14417 || orf19.1254 || SEC23 || || Putative GTPase-activating protein; regulated upon yeast-hypha switch; Spider biofilm repressed || 1 0.44 0.43 0.33 0.47 -0.80 -0.89 0.34 0.75 -0.14 0.19 0.15 -0.00 -0.07 0.11 -0.20 0.22
14418 || orf19.306 || USO5 || || Putative type II myosin heavy chain; transcription is induced upon filamentous growth and in response to alpha pheromone in SpiderM medium || 1 0.32 0.23 0.13 0.09 -0.71 -1.09 0.20 0.69 0.13 0.44 0.19 -0.16 0.20 0.17 0.01 0.07
14419 || orf19.895 || HOG1 || || MAP kinase of osmotic-, heavy metal-, and core stress response; role in regulation of glycerol, D-arabitol in response to stress; phosphorylated in response to H2O2 (Ssk1-dependent) or NaCl; mutant induces protective mouse immune response || 1 0.41 0.25 0.20 0.17 -0.69 -0.62 0.30 0.50 -0.02 0.18 0.29 0.01 0.18 0.01 0.17 -0.06
14420 || orf19.3207 || CCN1 || || G1 cyclin; required for hyphal growth maintenance (not initiation); cell-cycle regulated transcription (G1/S); Cdc28p-Ccn1p initiates Cdc11p S394 phosphorylation on hyphal induction; expression in S. cerevisiae inhibits pheromone response || 1 0.63 0.55 0.45 0.32 -1.47 -1.99 0.62 0.80 0.12 0.64 0.72 0.39 1.09 0.08 -0.12 -0.22
14421 || orf19.95 || || || Ortholog of S. cerevisiae : PRM5, C. dubliniensis CD36 : Cd36_60980, C. parapsilosis CDC317 : CPAR2_603060, Candida tenuis NRRL Y-1498 : CANTEDRAFT_113703 and Debaryomyces hansenii CBS767 : DEHA2F10032g || 1 0.85 0.43 0.65 0.32 -0.95 -2.02 0.51 1.44 0.12 0.89 0.36 0.67 1.34 -0.19 -0.59 0.02
14422 || orf19.3667 || || || Ortholog(s) have microtubule motor activity, protein homodimerization activity and kinesin complex localization || 1 0.53 0.24 0.63 0.54 -0.86 -1.87 0.31 0.63 0.05 0.50 0.11 0.42 0.50 0.15 -0.21 0.40
14423 || orf19.7293 || MPS1 || || Monopolar spindle protein, a putative kinase; essential for growth; periodic mRNA expression, peak at cell-cycle S/G2 phase || 1 -0.01 0.44 0.54 0.74 -1.04 -1.95 0.30 0.35 -0.10 0.68 0.59 0.31 0.50 0.08 -0.68 -0.33
14424 || orf19.2238 || LTE1 || || Protein similar to GDP/GTP exchange factors; repressed by alpha pheromone in SpiderM medium; flow model biofilm repressed || 1 0.87 0.99 0.35 0.63 -0.82 -1.79 0.59 1.17 0.36 0.63 0.70 0.23 1.13 0.50 -0.42 -1.17
14425 || orf19.2416.1 || MLC1 || || Microtubule-dependent localized protein; at Spitzenkorper and cytokinetic ring in hyphae; cell-cycle dependent localization to tip polarisome, bud neck in yeast and pseudohyphae; sumoylation target; rat catheter, Spider biofilm repressed || 1 0.71 0.76 0.16 0.16 -0.98 -1.99 1.11 1.68 0.48 0.79 1.16 0.28 1.06 1.15 -0.50 -0.46
14426 || orf19.2641 || ARP1 || || Putative centractin; induced upon adherence to polystyrene || 1 0.04 0.52 0.26 -0.11 -0.64 -1.14 0.27 0.74 0.26 0.46 0.56 0.24 0.23 0.39 0.00 -0.03
14427 || orf19.6526 || || || Ortholog(s) have COPI-coated vesicle, Golgi apparatus localization || 1 -0.24 0.16 -0.06 0.01 -0.70 -1.26 0.12 0.32 -0.07 0.52 0.12 0.25 0.19 0.37 -0.43 -0.25
14428 || orf19.385 || GCV2 || || Glycine decarboxylase P subunit; protein of glycine catabolism; repressed by Efg1; Hog1-induced; induced by Rim101 at acid pH; transcript induced in elevated CO2; stationary phase enriched protein || 1 0.49 0.43 -0.50 0.04 -1.92 -2.49 0.15 0.34 0.19 0.29 0.20 0.36 0.30 0.96 -0.86 -0.18
14429 || orf19.4376 || || || Protein of unknown function; Spider biofilm induced || 1 0.29 0.21 0.46 -0.07 -1.28 -2.01 0.26 1.12 0.62 0.39 0.49 -0.11 -0.55 0.41 -0.32 -0.59
14430 || orf19.2200 || || || Protein of unknown function; rat catheter biofilm repressed || 1 0.41 0.04 0.11 0.41 -0.75 -1.10 0.47 0.63 0.06 0.34 0.39 -0.25 -0.31 0.25 0.05 -0.13
14431 || orf19.2328 || || || Ortholog of C. dubliniensis CD36 : Cd36_10220, C. parapsilosis CDC317 : CPAR2_210530, Candida tenuis NRRL Y-1498 : CANTEDRAFT_105553 and Debaryomyces hansenii CBS767 : DEHA2G14432g || 1 0.46 0.50 0.30 0.10 -0.63 -1.25 0.14 0.44 -0.22 0.01 0.59 0.03 0.37 0.06 -0.18 0.10
14432 || orf19.242.2 || || || Ortholog(s) have endoplasmic reticulum localization || 1 0.67 0.81 -0.12 -0.04 -1.13 -1.61 0.50 0.91 -0.80 0.12 1.07 -0.04 0.80 -0.17 0.28 0.01
14433 || orf19.5268 || MED10 || || RNA polymerase II mediator complex subunit; possibly an essential gene, disruptants not obtained by UAU1 method || 1 0.28 0.09 0.06 0.08 -0.72 -1.08 0.25 0.71 0.00 -0.06 0.47 -0.13 0.72 0.64 -0.08 0.02
14434 || orf19.6936 || RAD53 || || Protein involved in regulation of DNA-damage-induced filamentous growth; putative component of cell cycle checkpoint; ortholog of S. cerevisiae Rad53p, protein kinase required for cell-cycle arrest in response to DNA damage || 1 -0.24 0.07 0.05 0.46 -0.35 -1.07 0.51 0.35 0.54 0.31 0.34 -0.27 0.21 0.35 -0.96 0.03
14435 || orf19.2274 || || || Ortholog of C. dubliniensis CD36 : Cd36_21450, Candida tropicalis MYA-3404 : CTRG_01739 and Candida albicans WO-1 : CAWG_05814 || 1 0.05 0.48 -0.19 0.32 -0.21 -1.15 0.50 0.23 0.55 0.95 0.31 -0.63 0.53 0.50 -1.21 -0.65
14436 || orf19.5762 || PGA61 || || Putative GPI-anchored protein || 1 -0.04 0.59 -1.00 0.29 -0.50 -2.14 0.89 0.80 -0.18 0.48 0.60 -0.10 1.14 0.66 -0.42 -0.45
14437 || orf19.4163 || || || Ortholog(s) have role in protein targeting to vacuole, receptor-mediated endocytosis, response to pheromone and actin cortical patch, cytosol, endosome, plasma membrane, ribosome localization || 1 0.31 0.42 -0.73 -0.15 -0.25 -0.77 0.41 0.35 -0.30 0.28 0.23 -0.11 0.39 0.61 0.01 -0.06
14438 || orf19.6789 || || || S. cerevisiae ortholog Nud1 is a spindle pole body outer plaque component; it acts through the mitotic exit network to specify asymmetric spindle pole body inheritance; Hap43-induced gene || 1 0.05 -0.14 -0.78 -0.20 -0.62 -1.37 -0.12 0.05 -0.95 -0.56 0.08 -0.44 0.37 0.06 -0.55 -0.06
14439 || orf19.5316 || FGR29 || || Protein lacking an ortholog in S. cerevisiae; transposon mutation affects filamentous growth; rat catheter biofilm repressed || 1 0.44 0.32 -0.64 -0.17 -0.89 -1.73 0.29 0.64 -0.40 -0.35 -0.05 -0.04 0.16 0.29 -0.04 0.01
14440 || orf19.1597 || ABG1 || || Vacuolar membrane protein; depletion causes abnormal vacuolar morphology, cell separation defect, sensitivity to cell wall stress, increased hyphal branching; essential, no mammalian homolog; Cyr1-regulated; rat catheter biofilm repressed || 1 0.03 0.03 -0.46 -0.17 -1.00 -1.27 0.34 0.44 -0.15 -0.20 0.29 -0.06 0.05 0.38 -0.23 -0.06
14441 || orf19.1597 || ABG1 || || Vacuolar membrane protein; depletion causes abnormal vacuolar morphology, cell separation defect, sensitivity to cell wall stress, increased hyphal branching; essential, no mammalian homolog; Cyr1-regulated; rat catheter biofilm repressed || 1 -0.10 -0.20 -0.82 -0.49 -1.15 -1.43 0.20 0.20 -0.58 -0.56 0.28 -0.11 -0.08 0.11 -0.30 -0.36
14442 || orf19.7329 || || || Ortholog(s) have ubiquitin-protein ligase activity || 1 0.07 -0.12 -0.64 -0.82 -0.59 -1.15 0.55 0.37 -0.30 -0.50 0.09 -0.75 -0.09 -0.14 -0.40 -0.11
14443 || orf19.4827 || ADE12 || || Adenylosuccinate synthase; upregulated in biofilm; decreased expression in hyphae vs yeast-form cells; not induced during GCN response, in contrast to S. cerevisiae ADE12, which is induced by Gcn4p; stationary phase-enriched protein || 1 0.27 -0.06 -0.73 -0.29 -0.74 -1.10 0.76 0.31 0.06 -0.31 0.27 -0.20 -0.21 -0.25 -0.38 -0.51
14444 || orf19.3281 || || || Ortholog(s) have histone demethylase activity (H3-K36 specific), methylated histone residue binding activity and role in histone demethylation || 1 0.15 0.43 -0.59 -0.55 -0.54 -1.09 0.23 0.05 0.16 -0.25 0.16 -0.21 -0.08 -0.46 -0.59 -0.41
14445 || orf19.1282 || CKS1 || || Ortholog(s) have histone binding, protein complex binding, protein homodimerization activity, protein kinase activator activity, ubiquitin binding activity || 1 0.14 0.26 0.15 -0.32 -0.52 -0.98 0.01 0.08 0.10 0.43 -0.19 0.10 -0.00 0.06 -0.71 -0.78
14446 || orf19.1508 || || || Protein of unknown function; transcript detected on high-resolution tiling arrays || 1 -0.35 -0.42 -0.52 0.34 -1.43 -0.57 0.08 0.08 -0.08 -0.04 -0.14 -0.11 0.55 0.01 -0.63 0.06
14447 || orf19.3629 || DSE1 || || Essential cell wall protein involved in cell wall integrity and rigidity; periodic mRNA expression peaks at M/G1 phase; Ace2p-induced; required for virulence in a mouse model of infection || 1 -0.18 -0.25 -0.42 -0.36 -3.11 -1.22 0.59 0.39 -0.10 -0.47 0.67 0.43 1.09 0.36 0.21 0.54
14448 || orf19.3629 || DSE1 || || Essential cell wall protein involved in cell wall integrity and rigidity; periodic mRNA expression peaks at M/G1 phase; Ace2p-induced; required for virulence in a mouse model of infection || 1 -0.53 -0.59 -1.25 -1.17 -3.29 -1.41 0.16 0.00 -0.54 -0.93 0.39 0.05 0.76 0.19 -0.16 0.10
14449 || orf19.7586 || CHT3 || || Major chitinase; secreted; functional homolog of S. cerevisiae Cts1p; 4 N-glycosylation motifs; possible O-mannosylation; putative signal peptide; hyphal-repressed; farnesol upregulated in biofilm; regulated by Efg1p, Cyr1p, Ras1p || 1 -0.49 -0.40 -0.58 -0.32 -2.04 -0.49 0.36 0.01 -0.64 -0.94 0.97 -0.22 0.44 -0.11 0.15 0.14
14450 || orf19.6925 || HTB1 || || Histone H2B; induced by adherence to polystyrene; amphotericin B, caspofungin repressed; flucytosine, fluconazole induced; Efg1 regulated; slow growth, increased white-to opaque switch in ectopic expression strains; Spider biofilm repressed || 1 -0.26 -0.36 0.11 0.25 -1.29 -1.28 -0.09 -0.01 -0.75 -0.86 0.69 -0.13 0.47 -0.13 -0.14 0.10
14451 || orf19.6925 || HTB1 || || Histone H2B; induced by adherence to polystyrene; amphotericin B, caspofungin repressed; flucytosine, fluconazole induced; Efg1 regulated; slow growth, increased white-to opaque switch in ectopic expression strains; Spider biofilm repressed || 1 -0.33 -0.46 0.18 0.24 -1.29 -1.17 -0.23 -0.05 -0.67 -0.74 0.61 0.12 0.34 0.01 -0.16 0.05
14452 || orf19.6924 || HTA1 || || Histone H2A; repressed in fkh2 mutant; amphotericin B repressed; farnesol regulated; RNA abundance regulated by tyrosol and cell density; Hap43-induced gene; Spider biofilm repressed || 1 -0.42 -0.44 -0.28 -0.31 -2.38 -2.00 0.03 0.16 -0.67 -0.87 1.21 0.18 0.25 0.31 -0.15 0.12
14453 || orf19.6924 || HTA1 || || Histone H2A; repressed in fkh2 mutant; amphotericin B repressed; farnesol regulated; RNA abundance regulated by tyrosol and cell density; Hap43-induced gene; Spider biofilm repressed || 1 -0.24 -0.23 -0.12 -0.12 -1.34 -1.82 -0.08 -0.09 -0.59 -0.67 1.00 0.26 0.50 0.28 0.02 0.26
14454 || orf19.2209 || YVC1 || || Putative vacuolar cation channel shock; repressed by alpha pheromone in SpiderM medium; flow model biofilm repressed || 1 -0.42 -0.42 -0.26 -0.30 -1.55 -1.56 -0.08 0.10 -0.70 0.02 0.24 -0.07 0.85 0.38 -0.62 -0.21
14455 || orf19.2209 || YVC1 || || Putative vacuolar cation channel shock; repressed by alpha pheromone in SpiderM medium; flow model biofilm repressed || 1 -0.34 -0.36 -0.24 -0.17 -1.70 -1.72 0.10 0.21 -0.42 0.12 0.25 -0.18 0.94 0.46 -0.56 -0.00
14456 || orf19.2758 || PGA38 || || Putative adhesin-like GPI-anchored protein; repressed during cell wall regeneration; possibly an essential gene, disruptants not obtained by UAU1 method; rat catheter and Spider biofilm repressed || 1 0.75 0.57 -0.51 -0.10 -4.52 -2.19 1.51 1.36 -0.12 -0.27 0.47 -0.64 1.27 0.48 -0.93 -0.56
14457 || orf19.2758 || PGA38 || || Putative adhesin-like GPI-anchored protein; repressed during cell wall regeneration; possibly an essential gene, disruptants not obtained by UAU1 method; rat catheter and Spider biofilm repressed || 1 0.06 0.01 -1.01 -0.56 -3.96 -2.63 0.91 0.92 -0.25 -0.21 0.07 -0.73 0.94 0.33 -1.08 -0.51
14458 || orf19.4910 || FGR41 || || Putative GPI-anchored adhesin-like protein; transposon mutation affects filamentous growth; Spider biofilm repressed || 1 0.15 0.11 -0.60 -0.10 -3.29 -2.07 0.67 0.47 -0.44 -0.66 0.29 -0.46 1.52 0.62 -0.47 -0.45
14459 || orf19.4910 || FGR41 || || Putative GPI-anchored adhesin-like protein; transposon mutation affects filamentous growth; Spider biofilm repressed || 1 0.24 -0.05 -0.40 0.01 -3.91 -1.95 0.75 0.45 -0.24 -0.64 0.20 -0.42 1.23 0.38 -0.40 0.01
14460 || orf19.1747 || KIP2 || || Putative kinesin-related motor protein involved in mitotic spindle positioning; repressed by alpha pheromone in SpiderM medium; periodic mRNA expression, peak at cell-cycle G2/M phase || 1 0.16 0.23 -0.56 -0.12 -2.61 -1.99 0.36 0.54 -0.20 0.31 0.19 -0.22 0.82 0.35 -0.29 0.00
14461 || orf19.5664 || HOF1 || || Ortholog of S. cerevisiae Hof1; a protein localized to the bud neck and required for cytokinesis in S. cerevisiae; periodic mRNA expression, peak at cell-cycle G2/M phase; mutant is viable || 1 0.01 -0.19 -0.33 -0.13 -2.44 -1.42 0.46 0.60 0.14 -0.05 0.60 -0.12 0.44 0.34 -0.56 0.25
14462 || orf19.3893 || SCW11 || || Cell wall protein; repressed in ace2 mutant; repressed in core caspofungin response; induced in high iron; possibly an essential gene, disruptants not obtained by UAU1 method; rat catheter and Spider biofilm repressed || 1 -0.29 -0.24 0.02 0.09 -3.43 -1.23 0.09 0.09 -0.27 -0.65 0.38 0.37 0.62 0.29 -0.75 0.53
14463 || orf19.3893 || SCW11 || || Cell wall protein; repressed in ace2 mutant; repressed in core caspofungin response; induced in high iron; possibly an essential gene, disruptants not obtained by UAU1 method; rat catheter and Spider biofilm repressed || 1 -0.26 -0.29 0.20 0.08 -3.11 -1.29 0.13 0.11 -0.30 -0.59 0.36 0.36 0.76 0.42 -0.61 0.08
14464 || orf19.1853 || HHT2 || || Putative histone H3; farnesol regulated; Hap43-induced; rat catheter and Spider biofilm repressed || 1 0.27 0.16 0.43 0.77 -4.84 -2.22 0.68 0.81 -0.19 -0.10 1.15 0.42 1.31 0.71 -0.16 0.51
14465 || orf19.1059 || HHF1 || || Putative histone H4; repressed in fkh2 mutant; regulated by Efg1; fluconazole induced; amphotericin B repressed; farnesol regulated; colony morphology-related gene regulation by Ssn6; Hap43-induced; rat catheter and Spider biofilm repressed || 1 0.18 -0.05 0.67 0.93 -2.80 -1.80 0.05 0.56 -0.28 -0.33 1.26 0.27 0.82 0.16 -0.29 0.05
14466 || orf19.1854 || HHF22 || || Putative histone H4; regulated by Efg1; flucytosine, fluconazole-induced; amphotericin B, caspofungin repressed; colony morphology-related gene regulation by Ssn6; Hap43-induced; rat catheter and Spider biofilm repressed || 1 0.13 -0.09 0.61 0.83 -3.39 -1.86 0.34 0.60 -0.35 -0.20 1.29 0.27 0.95 0.27 -0.20 0.20
14467 || orf19.1061 || HHT21 || || Putative histone H3; amphotericin B repressed; regulated by Efg1, farnesol; Hap43-induced; rat catheter and Spider biofilm repressed || 1 -0.37 -0.13 0.47 0.66 -5.46 -2.50 0.14 0.40 -0.48 -0.39 0.83 -0.05 0.83 0.23 -0.58 0.06
14468 || orf19.1052 || || || Predicted histone H2B; Hap43-induced gene; Spider biofilm repressed || 1 -0.16 -0.30 0.26 0.60 -2.99 -2.11 0.07 0.29 -0.67 -0.51 0.80 -0.16 0.64 -0.10 -0.46 -0.15
14469 || orf19.1059 || HHF1 || || Putative histone H4; repressed in fkh2 mutant; regulated by Efg1; fluconazole induced; amphotericin B repressed; farnesol regulated; colony morphology-related gene regulation by Ssn6; Hap43-induced; rat catheter and Spider biofilm repressed || 1 0.02 0.06 0.75 1.00 -3.25 -1.99 -0.07 0.33 -0.45 -0.37 0.88 0.12 0.51 0.05 -0.52 -0.40
14470 || orf19.1854 || HHF22 || || Putative histone H4; regulated by Efg1; flucytosine, fluconazole-induced; amphotericin B, caspofungin repressed; colony morphology-related gene regulation by Ssn6; Hap43-induced; rat catheter and Spider biofilm repressed || 1 -0.11 -0.24 0.38 0.99 -3.31 -1.94 -0.04 0.33 -0.32 -0.29 0.92 0.06 0.52 0.04 -0.50 -0.29
14471 || orf19.1052 || || || Predicted histone H2B; Hap43-induced gene; Spider biofilm repressed || 1 -0.15 -0.36 0.45 0.61 -3.30 -2.09 0.12 0.40 -0.43 -0.24 0.87 0.28 0.69 0.21 -0.54 0.20
14472 || orf19.1051 || HTA2 || || Putative histone H2A; farnesol regulated; rat catheter biofilm repressed; Spider biofilm repressed; Hap43-induced || 1 -0.08 -0.18 0.43 0.56 -2.71 -2.09 -0.11 0.42 -0.22 -0.17 0.70 -0.01 0.41 0.46 -0.52 0.03
14473 || orf19.1051 || HTA2 || || Putative histone H2A; farnesol regulated; rat catheter biofilm repressed; Spider biofilm repressed; Hap43-induced || 1 -0.08 -0.23 0.50 0.86 -2.89 -2.42 -0.10 0.60 -0.13 0.08 0.65 0.04 0.61 0.17 -0.82 -0.33
14474 || orf19.1051 || HTA2 || || Putative histone H2A; farnesol regulated; rat catheter biofilm repressed; Spider biofilm repressed; Hap43-induced || 1 -0.02 -0.14 0.13 0.43 -2.80 -2.43 0.22 0.62 -0.52 -0.07 1.10 0.08 0.70 0.47 -0.50 -0.10
14475 || orf19.1051 || HTA2 || || Putative histone H2A; farnesol regulated; rat catheter biofilm repressed; Spider biofilm repressed; Hap43-induced || 1 0.04 -0.01 0.01 0.28 -1.79 -2.20 0.16 0.71 -0.48 -0.10 0.93 -0.26 0.67 0.23 -0.48 -0.22
14476 || orf19.1061 || HHT21 || || Putative histone H3; amphotericin B repressed; regulated by Efg1, farnesol; Hap43-induced; rat catheter and Spider biofilm repressed || 1 0.17 -0.02 0.41 0.51 -1.36 -1.54 0.08 0.37 -0.21 -0.20 0.54 0.08 0.86 0.46 -0.29 -0.13
14477 || orf19.1853 || HHT2 || || Putative histone H3; farnesol regulated; Hap43-induced; rat catheter and Spider biofilm repressed || 1 0.10 0.19 0.31 0.60 -1.30 -1.50 0.17 0.39 -0.18 -0.20 0.55 0.07 0.72 0.35 -0.24 0.06
14478 || orf19.5137 || || || Protein of unknown function; regulated by Sef1, Sfu1, Hap43; Spider biofilm repressed || 1 0.44 0.41 0.29 0.63 -1.18 -1.62 0.16 0.35 -0.51 -0.21 0.53 0.01 0.88 0.20 -0.46 0.10
14479 || orf19.3667 || || || Ortholog(s) have microtubule motor activity, protein homodimerization activity and kinesin complex localization || 1 0.28 0.19 0.25 0.54 -1.53 -1.93 0.74 0.30 -0.07 0.22 0.28 -0.19 0.55 0.12 -0.67 0.12
14480 || orf19.3751 || || || Putative serine/threonine protein kinase; possibly an essential gene, disruptants not obtained by UAU1 method || 1 0.48 0.36 -0.41 0.18 -1.12 -1.26 0.44 0.43 0.37 0.54 0.16 -0.09 0.73 0.26 -0.46 -0.17
14481 || orf19.1747 || KIP2 || || Putative kinesin-related motor protein involved in mitotic spindle positioning; repressed by alpha pheromone in SpiderM medium; periodic mRNA expression, peak at cell-cycle G2/M phase || 1 0.61 0.49 -0.04 0.34 -2.05 -1.71 0.84 0.87 0.38 0.85 0.25 0.13 1.13 0.85 -0.12 0.04
14482 || orf19.6315 || || || Ortholog of C. dubliniensis CD36 : Cd36_30140, C. parapsilosis CDC317 : CPAR2_204040, Candida tenuis NRRL Y-1498 : CANTEDRAFT_114703 and Debaryomyces hansenii CBS767 : DEHA2G22880g || 1 0.35 0.26 -0.28 0.45 -2.00 -1.54 0.97 1.00 0.25 0.66 0.56 0.44 0.61 0.22 0.37 0.40
14483 || orf19.6315 || || || Ortholog of C. dubliniensis CD36 : Cd36_30140, C. parapsilosis CDC317 : CPAR2_204040, Candida tenuis NRRL Y-1498 : CANTEDRAFT_114703 and Debaryomyces hansenii CBS767 : DEHA2G22880g || 1 0.30 0.64 -0.38 0.41 -2.63 -1.73 0.52 0.72 0.14 0.32 0.40 0.04 0.76 0.09 0.14 0.38
14484 || orf19.1747 || KIP2 || || Putative kinesin-related motor protein involved in mitotic spindle positioning; repressed by alpha pheromone in SpiderM medium; periodic mRNA expression, peak at cell-cycle G2/M phase || 1 0.41 0.91 -0.59 -0.15 -2.56 -1.40 0.76 0.44 -0.20 0.38 0.11 0.08 1.33 0.88 0.17 0.54
14485 || orf19.1334 || || || Protein of unknown function; repressed by alpha pheromone in SpiderM medium || 1 0.06 0.17 -0.83 -0.72 -1.92 -2.00 1.35 0.81 0.51 0.88 0.91 -0.03 1.43 0.59 0.06 0.67
14486 || orf19.668 || TOS4 || || Putative fork-head transcription factor; rat catheter and Spider biofilm repressed || 1 -0.14 -0.22 -0.76 -0.24 -2.58 -2.92 1.01 1.57 0.32 0.58 1.27 0.07 1.00 0.96 -0.28 0.77
14487 || orf19.5316 || FGR29 || || Protein lacking an ortholog in S. cerevisiae; transposon mutation affects filamentous growth; rat catheter biofilm repressed || 1 0.18 0.33 -0.27 0.15 -1.01 -1.49 0.69 0.84 0.18 0.41 0.63 0.31 0.84 0.33 -0.39 0.27
14488 || orf19.364 || || || Putative vacuolar H+-ATPase subunit; possibly an essential gene, disruptants not obtained by UAU1 method; Spider biofilm repressed || 1 0.13 0.11 -0.25 -0.05 -0.82 -0.77 0.81 0.60 0.00 -0.01 0.49 0.01 0.44 -0.03 -0.05 0.35
14489 || orf19.364 || || || Putative vacuolar H+-ATPase subunit; possibly an essential gene, disruptants not obtained by UAU1 method; Spider biofilm repressed || 1 0.13 0.08 -0.21 -0.23 -0.81 -0.84 0.76 0.63 0.38 -0.03 0.43 0.01 0.19 0.09 -0.11 0.07
14490 || orf19.1012 || || || Ortholog(s) have clathrin binding activity, role in Golgi to vacuole transport, endosomal transport and AP-1 adaptor complex, cytosol, endosome, nucleus localization || 1 0.17 0.35 -0.64 -0.58 -1.71 -1.59 0.66 0.92 0.14 0.05 1.01 -0.02 0.17 0.50 -0.80 0.47
14491 || orf19.7377 || ASE1 || || Putative microtubule-associated protein; member of conserved Mcm1p regulon; periodic mRNA expression, peak at cell-cycle G2/M phase || 1 0.08 0.15 -0.28 -0.16 -0.88 -0.98 0.38 0.47 -0.14 -0.26 0.50 0.09 0.35 0.11 -0.46 0.23
14492 || orf19.1522 || || || Ortholog of C. dubliniensis CD36 : Cd36_16850, C. parapsilosis CDC317 : CPAR2_211990, Candida tenuis NRRL Y-1498 : cten_CGOB_00169 and Debaryomyces hansenii CBS767 : DEHA2G03036g || 1 0.07 0.40 -0.56 -0.18 -1.05 -1.28 0.60 0.76 -0.18 -0.20 1.08 0.41 1.11 0.53 -0.17 0.65
14493 || orf19.1351 || || || Ortholog of C. parapsilosis CDC317 : CPAR2_407000, C. dubliniensis CD36 : Cd36_22440, Candida tenuis NRRL Y-1498 : cten_CGOB_00049 and Lodderomyces elongisporus NRLL YB-4239 : LELG_02401 || 1 0.33 0.04 -0.88 -0.02 -1.12 -2.03 0.79 1.06 -0.51 0.20 0.51 0.16 1.29 0.63 -0.66 0.25
14494 || orf19.1223 || DBF2 || || Essential serine/threonine protein kinase involved in mitotic spindle formation and cytokinesis; required for septum formation, exit from mitosis, and normal hyphal morphogenesis; virulence-group-correlated expression || 1 0.44 0.34 -0.60 -0.18 -1.77 -1.35 0.18 0.45 -0.04 0.19 0.78 0.18 0.62 0.56 0.03 0.70
14495 || orf19.1223 || DBF2 || || Essential serine/threonine protein kinase involved in mitotic spindle formation and cytokinesis; required for septum formation, exit from mitosis, and normal hyphal morphogenesis; virulence-group-correlated expression || 1 0.26 0.18 -0.36 0.09 -1.83 -1.25 -0.23 0.35 -0.38 -0.10 0.77 -0.00 0.43 -0.01 -0.17 0.49
14496 || orf19.6163 || CSE4 || || Centromeric histone H3 variant; role in structural changes of centromeric nucleosomes during cell cycle; 4 nucleosomes bind 1 centromere, each has 1 Cse4 molecule during most of cell cycle, 2 molecules in anaphase; Spider biofilm repressed || 1 0.21 0.05 -0.08 0.65 -2.93 -1.54 0.66 1.48 0.24 0.48 1.50 0.46 0.81 0.45 -0.61 0.06
14497 || orf19.1446 || CLB2 || || B-type mitotic cyclin (cyclin-dependent protein kinase regulatory subunit); essential; required for wild-type mitotic exit; role in cell polarization; interacts with catalytic subunit Cdk1; Spider biofilm repressed || 1 -0.19 -0.18 -0.46 -0.34 -2.26 -1.07 0.53 0.66 0.81 0.49 0.67 0.47 0.56 0.16 -0.17 0.03
14498 || orf19.1765 || || || Secreted protein; fluconazole-induced || 1 -0.58 -0.16 -0.50 0.17 -1.70 -1.14 0.56 0.29 0.32 0.20 0.80 0.32 0.39 0.44 0.34 0.38
14499 || orf19.3928 || || || Putative transcription factor with zinc finger DNA-binding motif || 1 0.03 -0.08 -0.04 -0.24 -1.49 -1.07 0.03 0.42 -0.28 -0.18 0.70 0.53 0.12 0.35 0.37 0.58
14500 || orf19.3928 || || || Putative transcription factor with zinc finger DNA-binding motif || 1 0.16 0.10 0.09 0.05 -1.00 -0.81 0.18 0.39 0.08 0.06 0.34 0.60 0.23 0.20 0.29 0.41
14501 || orf19.1773 || RAP1 || || Transcription factor; binds telomeres and regulatory sequences in DNA; involved in telomere maintenance; represses hyphal growth under yeast-favoring conditions; similar to (but shorter than) S. cerevisiae Rap1 || 1 0.36 0.31 0.11 0.17 -1.49 -0.86 0.34 0.30 0.27 0.31 0.65 0.41 -0.03 0.52 -0.01 0.60
14502 || orf19.7020 || || || Protein similar to S. cerevisiae Kex1p, which is a pheromone-processing peptidase; possible Kex2p substrate || 1 0.23 0.14 -0.16 0.01 -0.89 -1.00 0.39 0.17 0.16 0.01 0.40 0.34 0.06 0.77 -0.08 0.20
14503 || orf19.2184 || || || Putative fumarylacetoacetate hydrolase; clade-associated gene expression; rat catheter and Spider biofilm repressed || 1 0.02 -0.16 -0.35 -0.16 -1.47 -1.07 0.11 0.31 -0.00 -0.12 -0.23 -0.13 -0.08 0.37 -0.12 0.31
14504 || orf19.5816 || EBP7 || || Putative NADPH oxidoreductase; mutation confers hypersensitivity to toxic ergosterol analog; oxidative stress-induced via Cap1p || 1 0.02 0.17 -0.02 0.06 -1.82 -0.98 -0.05 -0.03 -0.53 -0.30 0.10 -0.29 -0.22 0.59 -0.90 0.34
14505 || orf19.5816 || EBP7 || || Putative NADPH oxidoreductase; mutation confers hypersensitivity to toxic ergosterol analog; oxidative stress-induced via Cap1p || 1 0.11 0.03 0.20 0.61 -1.30 -0.73 0.34 0.19 0.12 -0.17 0.18 -0.01 -0.22 0.73 -0.59 0.51
14506 || orf19.5004 || RAD54 || || Putative DNA-dependent ATPase involved in DNA repair; induced under hydroxyurea treatment; plays an essential role during mitotic growth; mutants display aberrant cell and nuclear morphology || 1 0.11 0.15 0.03 0.27 -0.81 -0.99 0.09 0.48 0.11 -0.15 0.36 0.31 -0.48 0.43 -0.53 0.29
14507 || orf19.6863 || VPH1 || || Vacuolar H(+)-ATPase; transcription regulated by Nrg1, Mig1, and Tup1 || 1 0.25 -0.03 0.29 0.55 -0.62 -0.51 -0.01 0.18 -0.08 -0.14 0.13 0.28 -0.04 0.00 -0.11 0.14
14508 || orf19.4623.3 || NHP6A || || Putative non-histone chromatin component; RNA abundance regulated by tyrosol,cell density; Hap43-induced; amphotericin B, caspofungin repressed; 5'-UTR intron; rat catheter and Spider biofilm repressed || 1 0.05 -0.05 0.58 0.96 -1.83 -1.35 0.29 0.69 0.17 -0.17 1.20 0.81 0.79 0.66 -0.39 0.45
14509 || orf19.6925 || HTB1 || || Histone H2B; induced by adherence to polystyrene; amphotericin B, caspofungin repressed; flucytosine, fluconazole induced; Efg1 regulated; slow growth, increased white-to opaque switch in ectopic expression strains; Spider biofilm repressed || 1 -0.33 -0.15 0.29 0.55 -1.08 -0.78 0.25 0.32 -0.51 -0.41 0.78 0.32 0.46 0.05 -0.10 0.47
14510 || orf19.6925 || HTB1 || || Histone H2B; induced by adherence to polystyrene; amphotericin B, caspofungin repressed; flucytosine, fluconazole induced; Efg1 regulated; slow growth, increased white-to opaque switch in ectopic expression strains; Spider biofilm repressed || 1 -0.19 -0.26 0.43 0.61 -1.03 -0.67 0.03 0.03 -0.48 -0.36 0.75 0.34 0.56 0.28 0.07 0.36
14511 || orf19.6925 || HTB1 || || Histone H2B; induced by adherence to polystyrene; amphotericin B, caspofungin repressed; flucytosine, fluconazole induced; Efg1 regulated; slow growth, increased white-to opaque switch in ectopic expression strains; Spider biofilm repressed || 1 -0.07 -0.32 0.82 0.75 -1.13 -0.76 -0.13 -0.01 -0.47 -0.35 0.75 0.62 0.45 0.41 0.06 0.81
14512 || orf19.5092 || || || Ortholog of C. parapsilosis CDC317 : CPAR2_207660.1, C. dubliniensis CD36 : Cd36_07680, Candida tenuis NRRL Y-1498 : CANTEDRAFT_113324 and Debaryomyces hansenii CBS767 : DEHA2C11088g || 1 0.11 0.18 0.08 0.19 -0.53 -1.21 0.54 0.36 0.12 -0.05 0.65 0.50 0.28 -0.21 -0.60 0.41
14513 || orf19.1986 || ARO2 || || Putative chorismate synthase; fungal-specific (no human or murine homolog); protein level decreased in stationary phase yeast cultures; GlcNAc-induced protein || 1 -0.03 0.02 -0.57 -0.04 -0.21 -1.18 -0.05 0.24 0.20 0.02 0.40 -0.05 0.01 0.25 -0.11 0.12
14514 || orf19.6124 || ACE2 || || Transcription factor; similar to S. cerevisiae Ace2 and Swi5; regulates morphogenesis, cell separation, adherence, virulence in a mice; mutant is hyperfilamentous; rat catheter and Spider biofilm induced || 1 -0.11 -0.17 -0.42 -0.15 -0.11 -1.45 0.07 0.34 -0.04 -0.18 0.30 0.15 0.29 0.24 -0.74 0.53
14515 || orf19.3648 || || || Ortholog(s) have crossover junction endodeoxyribonuclease activity, transcription coactivator activity || 1 -0.30 -0.00 -0.31 -0.40 -0.04 -1.11 0.17 0.16 0.22 0.07 0.53 0.42 0.41 0.11 -0.54 0.35
14516 || orf19.3648 || || || Ortholog(s) have crossover junction endodeoxyribonuclease activity, transcription coactivator activity || 1 -0.30 -0.34 -0.21 -0.11 -0.05 -1.00 -0.30 0.08 0.05 0.05 0.33 0.89 -0.15 0.18 -0.55 0.51
14517 || orf19.3356 || ESP1 || || Putative caspase-like cysteine protease; mutation confers increased sensitivity to nocodazole; periodic mRNA expression, peak at cell-cycle S/G2 phase; mRNA binds She3 || 1 0.02 -0.09 0.03 0.05 -0.24 -0.74 -0.11 0.15 0.19 0.05 0.15 0.39 0.17 0.08 -0.77 0.08
14518 || orf19.3216 || || || Similar to Rab GTPase activators; Hap43p-induced gene || 1 0.25 0.16 -0.05 0.50 -0.94 -1.11 -0.05 0.13 0.06 0.44 0.37 0.89 -0.23 0.34 -0.17 -0.03
14519 || orf19.3216 || || || Similar to Rab GTPase activators; Hap43p-induced gene || 1 0.17 0.04 -0.14 0.23 -0.44 -0.83 0.14 0.08 -0.15 0.18 0.01 0.49 -0.09 0.10 -0.11 0.01
14520 || orf19.3216 || || || Similar to Rab GTPase activators; Hap43p-induced gene || 1 -0.12 -0.14 -0.22 0.32 -0.55 -1.00 0.11 -0.08 -0.21 0.25 -0.19 0.59 -0.07 0.03 -0.34 -0.21
14521 || orf19.5242 || CDC6 || || Putative ATP-binding protein with a predicted role in DNA replication; member of conserved Mcm1p regulon; periodic mRNA expression, peak at cell-cycle M/G1 phase || 1 0.62 -0.32 -1.10 -0.51 -1.06 -2.45 -0.23 0.08 -0.21 1.23 -0.04 1.22 -0.17 -0.25 -1.08 -0.14
14522 || orf19.3111 || PRA1 || || Cell surface protein that sequesters zinc from host tissue; enriched at hyphal tips; released extracellularly; binds to host complement regulators; mediates leukocyte adhesion and migration; immunogenic in mouse; produced at ambient pH || 1 -0.14 0.27 -0.26 -0.44 -0.91 -2.50 0.26 -0.30 -0.40 0.36 0.32 0.93 -0.77 -0.31 -0.40 0.67
14523 || orf19.1112 || BUD7 || || Ortholog(s) have role in Golgi to plasma membrane transport, fungal-type cell wall chitin biosynthetic process and cell division site, clathrin-coated vesicle, cytosol, exomer complex, nucleus, ribosome localization || 1 0.21 0.27 -0.21 -0.22 -0.33 -0.86 -0.08 -0.16 -0.63 0.15 0.18 0.18 -0.26 0.21 -0.21 0.19
14524 || orf19.4865 || || || Ortholog(s) have phosphatidylinositol-3,5-bisphosphate 5-phosphatase activity, phosphatidylinositol-3-phosphatase activity, phosphatidylinositol-4-phosphate phosphatase activity and role in phosphatidylinositol dephosphorylation || 1 0.28 0.07 -0.24 0.11 -0.67 -0.87 0.02 0.03 -0.34 -0.05 0.11 0.06 -0.15 -0.17 -0.67 0.29
14525 || orf19.4257 || INT1 || || Protein structurally similar to alpha-subunit of human leukocyte integrin; role in morphogenesis, adhesion, and mouse cecal colonization and systemic virulence; similar to S. cerevisiae Bud4; Hap43-induced gene || 1 0.21 -0.41 -0.98 -0.44 -1.88 -1.57 0.40 -0.03 -0.70 -0.63 1.05 0.27 -0.12 -0.37 -1.07 0.49
14526 || orf19.2426 || || || Predicted HD domain metal dependent phosphohydrolase; Spider biofilm repressed || 1 -0.10 0.05 -0.44 -0.55 -1.42 -1.21 -0.38 0.18 -0.74 0.17 0.80 0.43 -0.01 -0.00 -0.66 1.11
14527 || orf19.2426 || || || Predicted HD domain metal dependent phosphohydrolase; Spider biofilm repressed || 1 0.17 -0.13 -0.34 -0.50 -0.91 -0.95 -0.49 0.12 -0.71 0.16 0.86 0.13 0.14 -0.19 -0.84 0.75
14528 || orf19.95 || || || Ortholog of S. cerevisiae : PRM5, C. dubliniensis CD36 : Cd36_60980, C. parapsilosis CDC317 : CPAR2_603060, Candida tenuis NRRL Y-1498 : CANTEDRAFT_113703 and Debaryomyces hansenii CBS767 : DEHA2F10032g || 1 -0.10 -0.35 -0.23 -0.18 -1.24 -1.23 -0.10 0.31 -0.27 0.43 0.80 1.03 0.51 0.12 -0.98 0.51
14529 || orf19.2228 || || || Ortholog(s) have actin filament binding, actin monomer binding activity and role in actin cortical patch organization, actin filament depolymerization, actin filament severing, sequestering of actin monomers || 1 0.18 0.02 -0.55 -0.32 -0.51 -0.87 0.15 0.23 -0.77 -0.02 0.59 0.42 0.07 0.17 -0.04 0.33
14530 || orf19.1993 || || || Ortholog(s) have structural molecule activity, role in proteasome assembly, ubiquitin-dependent protein catabolic process and nucleus, proteasome regulatory particle, lid subcomplex, proteasome storage granule localization || 1 0.07 0.08 -0.50 -0.38 -0.51 -0.52 -0.01 0.06 -0.40 0.23 0.32 0.07 -0.10 0.01 0.23 0.32
14531 || orf19.2087 || SAS2 || || Predicted histone acetyltransferase involved in histone H4 acetylation; member of MYST family || 1 -0.44 -0.32 0.10 -0.85 -0.17 -1.46 0.27 -0.03 -0.15 0.81 0.64 0.30 -0.34 0.06 -0.01 0.35
14532 || orf19.2087 || SAS2 || || Predicted histone acetyltransferase involved in histone H4 acetylation; member of MYST family || 1 -0.49 -0.53 -0.70 -0.47 -0.06 -1.12 0.19 0.07 -0.17 1.06 0.60 0.60 -0.35 0.08 -0.64 -0.24
14533 || orf19.5242 || CDC6 || || Putative ATP-binding protein with a predicted role in DNA replication; member of conserved Mcm1p regulon; periodic mRNA expression, peak at cell-cycle M/G1 phase || 1 -1.09 -0.11 -0.19 -0.03 0.56 -2.11 -0.26 0.07 -0.00 1.23 0.40 0.87 0.05 -0.67 -0.58 0.07
14534 || orf19.1170 || ARO7 || || Putative chorismate mutase; fungal-specific (no human or murine homolog); alkaline upregulated || 1 -0.61 -0.22 -0.02 -0.21 -0.32 -0.91 -0.31 -0.17 0.20 0.66 0.08 0.23 0.14 -0.27 -0.36 -0.31
14535 || orf19.2216 || PDS5 || || Putative protein with a predicted role in establishment and maintenance of sister chromatid condensation and cohesion; cell-cycle regulated periodic mRNA expression || 1 -0.63 -0.79 -0.12 -0.03 -0.76 -1.01 -0.76 0.23 -0.02 0.81 0.50 0.25 0.10 0.67 -0.54 0.28
14536 || orf19.2216 || PDS5 || || Putative protein with a predicted role in establishment and maintenance of sister chromatid condensation and cohesion; cell-cycle regulated periodic mRNA expression || 1 -0.32 -0.45 -0.19 0.29 -0.34 -1.27 -0.51 0.30 -0.22 0.77 0.52 -0.06 0.06 0.49 0.01 0.24
14537 || orf19.6610 || || || Ortholog(s) have microtubule plus-end binding, structural constituent of cytoskeleton activity || 1 -0.26 -0.44 -0.34 -0.04 -0.89 -1.71 -0.06 0.27 -0.27 1.03 0.63 -0.02 0.49 0.23 -0.61 0.35
14538 || orf19.7564 || DPB2 || || Probable subunit of DNA polymerase II (DNA polymerase epsilon), similar to S. cerevisiae Dpb2p; essential for viability; rat catheter biofilm induced || 1 -0.01 0.01 -0.47 -0.13 -0.59 -2.08 -0.40 0.23 -0.67 0.88 1.22 0.55 -0.18 0.59 -0.53 -0.31
14539 || orf19.3211 || RCF3 || || Putative heteropentameric replication factor C subunit; transcription is induced upon filamentous growth || 1 0.03 0.10 -0.30 -0.09 -0.02 -1.24 -0.07 0.47 0.08 0.97 0.59 0.40 -0.01 0.42 -0.46 -0.13
14540 || orf19.4136 || YBL053 || || Ortholog(s) have protein heterodimerization activity || 1 -0.01 -0.00 -0.12 0.14 -0.13 -1.02 -0.32 0.82 -0.06 1.12 0.87 -0.23 -0.03 0.25 -0.86 -0.36
14541 || orf19.547 || || || Ortholog(s) have 5'-flap endonuclease activity, single-stranded DNA 5'-3' exodeoxyribonuclease activity || 1 -0.26 -0.16 0.57 0.29 -0.18 -0.69 -0.06 0.62 -0.17 1.06 0.87 0.14 0.04 0.34 -0.50 0.02
14542 || orf19.1598 || ERG24 || || C-14 sterol reductase, has a role in ergosterol biosynthesis; mutation confers increased sensitivity to dyclonine; rat catheter and Spider biofilm repressed || 1 -0.62 -0.55 -0.13 0.08 -0.41 -1.07 -0.40 -0.25 0.43 0.12 0.24 -0.03 -0.10 0.40 -0.89 0.07
14543 || orf19.4378 || PPH3 || || Putative catalytic subunit of protein phosphatase complex; functions with regulatory subunit Psy2p in dephosphorylation of Rad53p in response to DNA damage; dephosphorylates Rfa2p in G1 phase; ortholog of S. cerevisiae Pph3p || 1 -0.34 -0.88 0.20 0.15 -0.56 -1.42 -0.82 -0.33 -0.41 -0.17 0.35 -0.04 -0.60 0.12 -0.75 0.12
14544 || orf19.5999 || DYN1 || || Dynein heavy chain; motor protein that moves to microtubule minus end; required for yeast cell separation, spindle positioning, nuclear migration, hyphal growth; regulated by Mig1, Hap43; flow model and rat catheter biofilm repressed || 1 -0.49 -0.46 0.20 0.16 -0.62 -0.94 -0.37 0.16 -0.30 -0.16 0.43 0.09 -0.78 -0.19 -0.94 0.66
14545 || orf19.5999 || DYN1 || || Dynein heavy chain; motor protein that moves to microtubule minus end; required for yeast cell separation, spindle positioning, nuclear migration, hyphal growth; regulated by Mig1, Hap43; flow model and rat catheter biofilm repressed || 1 -0.31 -0.29 -0.02 0.08 -0.39 -0.88 -0.35 -0.10 -0.21 -0.01 0.79 0.10 -0.56 0.06 -0.85 0.80
14546 || orf19.2093 || RFA1 || || Putative DNA replication factor A; RNA abundance regulated by cell cycle, tyrosol and cell density || 1 -0.17 -0.20 -0.23 -0.15 -0.30 -1.56 -0.23 0.62 -0.60 0.16 0.37 -0.48 -0.38 0.12 -1.03 0.21
14547 || orf19.2093 || RFA1 || || Putative DNA replication factor A; RNA abundance regulated by cell cycle, tyrosol and cell density || 1 -0.19 -0.11 -0.11 -0.19 -0.24 -1.74 -0.01 0.85 -0.44 0.46 0.61 -0.35 -0.35 0.41 -1.18 0.47
14548 || orf19.2093 || RFA1 || || Putative DNA replication factor A; RNA abundance regulated by cell cycle, tyrosol and cell density || 1 -0.25 -0.30 -0.35 -0.10 -0.32 -1.52 0.02 0.92 -0.34 0.47 0.69 0.04 -0.32 0.47 -1.08 0.54
14549 || orf19.2093 || RFA1 || || Putative DNA replication factor A; RNA abundance regulated by cell cycle, tyrosol and cell density || 1 -0.48 -0.43 -0.59 -0.48 -0.35 -1.55 -0.20 0.75 -0.49 0.48 0.69 -0.27 -0.40 0.50 -1.23 0.38
14550 || orf19.2093 || RFA1 || || Putative DNA replication factor A; RNA abundance regulated by cell cycle, tyrosol and cell density || 1 -0.56 -0.44 -0.69 -0.67 -0.25 -1.87 0.02 0.77 -0.47 0.59 0.78 -0.23 -0.48 0.62 -1.28 0.22
14551 || orf19.5164 || ECM39 || || Putative mannosyltransferase similar to S. cerevisiae Ecm39p, which has a role in Calcofluor white resistance; predicted Kex2p substrate; has HKEXRF motif || 1 -0.19 -0.22 -0.43 -0.43 -0.36 -1.06 0.22 0.56 0.15 0.44 0.08 -0.14 -0.21 0.44 -0.56 0.11
14552 || orf19.7466 || ACC1 || || Putative acetyl-coenzyme-A carboxylases; regulated by Efg1; amphotericin B repressed; caspofungin repressed; 5'-UTR intron; gene used for strain identification by multilocus sequence typing; Hap43-induced; flow model biofilm repressed || 1 -0.11 -0.15 -0.77 -0.91 -1.42 0.26 1.02 0.48 0.38 -0.28 -0.49 0.73 -1.65 0.20
14553 || orf19.7466 || ACC1 || || Putative acetyl-coenzyme-A carboxylases; regulated by Efg1; amphotericin B repressed; caspofungin repressed; 5'-UTR intron; gene used for strain identification by multilocus sequence typing; Hap43-induced; flow model biofilm repressed || 1 -0.28 -0.24 -0.83 -0.77 -0.99 -1.59 0.25 0.96 0.30 0.42 0.39 -0.62 -0.44 0.55 -1.94 0.23
14554 || orf19.7402 || DOT1 || || Putative modulator of white-opaque switching || 1 -0.70 -0.65 -0.58 -0.30 -0.73 -1.06 -0.21 0.38 -0.23 0.06 -0.00 -0.16 -0.44 0.62 -1.31 0.08
14555 || orf19.4435 || || || Ortholog(s) have structural constituent of cytoskeleton activity, role in microtubule nucleation and spindle pole body localization || 1 -0.81 -0.78 -0.64 -0.72 -0.38 -1.53 -0.49 0.15 -0.94 0.09 0.36 -0.20 -0.32 0.73 -1.38 0.14
14556 || orf19.4435 || || || Ortholog(s) have structural constituent of cytoskeleton activity, role in microtubule nucleation and spindle pole body localization || 1 -0.76 -0.69 -0.67 -0.60 -0.56 -1.84 -0.42 -0.03 -0.70 0.14 0.19 -0.42 -0.25 0.03 -1.42 -0.17
14557 || orf19.2796 || || || Ortholog(s) have DNA-directed DNA polymerase activity, role in DNA replication initiation, telomere capping and alpha DNA polymerase:primase complex, cytosol, nuclear envelope localization || 1 -0.29 -0.64 -1.10 -0.78 -1.30 -1.35 -0.37 0.17 -0.79 0.56 0.56 -0.86 -0.44 0.58 -1.61 -0.01
14558 || orf19.979 || FAS1 || || Beta subunit of fatty-acid synthase; multifunctional enzyme; Hap43, fluconazole-induced; amphotericin B, caspofungin repressed; macrophage/pseudohyphal-induced; flow model and Spider biofilm repressed || 1 -0.50 -0.50 -1.13 -0.87 -0.62 -1.21 -0.29 -0.03 -0.55 -0.43 0.17 -0.75 -0.99 -0.01 -1.72 -0.13
14559 || orf19.979 || FAS1 || || Beta subunit of fatty-acid synthase; multifunctional enzyme; Hap43, fluconazole-induced; amphotericin B, caspofungin repressed; macrophage/pseudohyphal-induced; flow model and Spider biofilm repressed || 1 -0.24 -0.32 -0.53 -0.20 -0.48 -0.89 -0.22 0.17 -0.04 -0.05 0.33 -0.45 -0.74 0.15 -1.46 0.09
14560 || orf19.5949 || FAS2 || || Alpha subunit of fatty-acid synthase; required for virulence in mouse systemic infection and rat oropharyngeal infection models; regulated by Efg1; fluconazole-induced; amphotericin B repressed; flow model and Spider biofilm repressed || 1 -0.51 -0.65 -0.50 -0.42 -1.11 -1.83 -0.24 0.17 -0.17 -0.13 0.14 -0.98 -0.97 -0.21 -2.52 -0.42
14561 || orf19.1998 || || || Ortholog of C. dubliniensis CD36 : Cd36_16140, C. parapsilosis CDC317 : CPAR2_213870, Candida tenuis NRRL Y-1498 : CANTEDRAFT_92202 and Debaryomyces hansenii CBS767 : DEHA2A01980g || 1 -0.11 -0.01 -0.66 -0.89 -0.41 -1.16 0.07 -0.04 -0.24 -0.08 0.35 -0.31 -0.38 0.34 -1.15 -0.14
14562 || orf19.5589 || || || Protein of unknown function; transcript detected on high-resolution tiling arrays || 1 -0.78 -0.59 -0.17 -2.14 -1.27 -1.84 0.19 -0.08 -0.79 0.27 0.31 -0.35 -0.90 0.59 -1.43 0.83
14563 || orf19.4228 || || || Protein with a role in insertion of tail-anchored proteins into the ER membrane; Spider biofilm repressed || 1 -0.23 -0.39 -0.09 -0.06 -0.33 -0.52 -0.09 -0.02 -0.17 0.04 -0.11 -0.08 -0.51 0.25 -0.43 -0.05
14564 || orf19.1883 || YCS4 || || Putative condensin complex subunit; cell-cycle regulated periodic mRNA expression || 1 -0.30 -0.22 -0.47 -0.48 -0.02 -0.81 -0.43 -0.27 -0.37 -0.04 -0.24 0.04 -0.66 0.26 -1.07 0.33
14565 || orf19.1654 || || || Predicted membrane protein; induced by prostaglandins || 1 -0.23 -0.29 -0.53 -0.90 -0.66 -0.56 0.32 -0.02 0.02 -0.87 -0.04 -0.52 0.52 0.62 -0.75 0.28
14566 || orf19.4513 || || || Protein of unknown function; mutants are viable; rat catheter and Spider biofilm induced || 1 0.19 0.15 -0.87 -0.59 -0.81 -1.04 0.63 -0.04 0.13 -1.07 -0.52 -1.07 0.04 0.10 -0.94 0.00
14567 || orf19.6305 || || || Hydroxytrimethyllysine aldolase, the second enzyme in the carnitine biosynthesis pathway; rat catheter biofilm repressed || 1 0.00 -0.00 -0.41 -0.19 -0.64 -0.62 0.09 0.15 -0.23 -0.97 -0.21 0.01 -0.34 -0.01 -0.39 -0.14
14568 || orf19.4624 || HRT2 || || Protein described as having a role in Ty3 transposition; repressed in hyphae; stationary phase enriched protein; rat catheter and Spider biofilm repressed || 1 -0.04 -0.17 -0.59 -0.58 -0.84 -0.71 -0.03 0.17 -0.74 -0.94 0.39 0.21 -0.46 0.43 -0.81 0.72
14569 || orf19.796 || HYM1 || || Protein of RAM cell wall integrity signaling network; involved in regulation of Ace2 activity and cellular morphogenesis; role in cell separation, azole sensitivity; required for hyphal growth || 1 -0.14 -0.01 -0.32 -0.41 -0.55 -0.38 0.17 0.27 -0.11 -0.44 0.17 -0.17 -0.18 -0.20 -0.65 0.25
14570 || orf19.2351 || NIT3 || || Putative nitrilase; regulated by Gcn2p and Gcn4p; protein present in exponential and stationary growth phase yeast cultures || 1 -0.10 -0.25 -0.15 -0.33 -1.07 -0.89 0.54 0.33 0.56 -0.83 -0.02 0.03 -0.49 0.05 -0.29 0.16
14571 || orf19.5877 || ATF1 || || Putative alcohol acetyltransferase; caspofungin repressed; expression depends on Tac1p || 1 -0.42 -0.25 0.10 0.13 -1.26 -0.94 0.90 0.40 0.67 -0.99 -0.53 -0.45 -0.62 0.11 -0.78 0.33
14572 || orf19.6411 || || || Protein similar to S. cerevisiae Vac14p; a protein involved in regulated synthesis of PtdIns(3,5)P(2); transposon mutation affects filamentous growth || 1 -0.12 0.11 -0.02 -0.20 -0.70 -0.46 0.34 0.12 -0.08 -0.39 -0.68 -0.36 -0.16 0.18 -0.57 0.02
14573 || orf19.7261 || GDI1 || || Putative Rab GDP-dissociation inhibitor; GlcNAc-induced protein; Spider biofilm repressed || 1 -0.13 -0.07 0.08 0.01 -0.65 -0.25 0.12 0.08 -0.17 -0.19 -0.38 -0.29 -0.21 -0.23 -0.38 -0.19
14574 || orf19.2492 || STE3 || || Protein similar to S. cerevisiae Ste3p, the receptor for a-factor mating pheromone; alpha mating-type-specific transcription || 1 -0.58 -0.95 -0.12 -1.25 -0.20 -0.17 -0.73 0.57 -0.07 0.46 0.52 -1.37 -0.58
14575 || orf19.6264 || || || Ortholog of C. dubliniensis CD36 : Cd36_06080, C. parapsilosis CDC317 : CPAR2_803360, Candida tenuis NRRL Y-1498 : CANTEDRAFT_112428 and Debaryomyces hansenii CBS767 : DEHA2G15532g || 1 -0.26 -0.18 0.13 0.57 -0.50 -0.34 0.14 0.03 0.05 0.30 0.22 0.30 0.17 -0.04 -0.26 -0.03
14576 || orf19.6575 || || || Protein of unknown function; rat catheter biofilm repressed || 1 -1.15 -0.85 -1.49 0.90 -0.54 -0.43 0.19 -0.01 0.50 0.47 0.15 0.60 -0.41 -0.01
14577 || orf19.4867 || SWE1 || || Putative protein kinase with a role in control of growth and morphogenesis, required for full virulence; mutant cells are small, rounded, and sometimes binucleate; not required for filamentous growth; mutant is hypersensitive to caspofungin || 1 -0.54 -0.59 -0.84 0.06 -0.02 -1.13 -0.45 -0.19 -0.58 -0.47 0.48 0.26 -0.02 0.06 -0.17 -0.09
14578 || orf19.5623 || ARP4 || || Subunit of the NuA4 histone acetyltransferase complex || 1 -0.26 -0.15 -0.37 0.06 -0.00 -0.59 -0.13 0.15 -0.24 -0.31 -0.09 0.38 0.18 0.11 -0.15 0.06
14579 || orf19.4861 || || || Protein of unknown function; rat catheter biofilm repressed || 1 -0.38 -0.41 -0.53 0.47 0.01 -1.23 -0.59 0.12 -0.18 0.30 -0.37 0.38 0.35 0.05 0.12 0.13
14580 || orf19.2916 || || || Ortholog of C. dubliniensis CD36 : Cd36_45740, C. parapsilosis CDC317 : CPAR2_401900, Candida tenuis NRRL Y-1498 : CANTEDRAFT_116046 and Pichia stipitis Pignal : PICST_28890 || 1 -0.55 0.13 -0.76 1.04 -0.28 -1.84 -0.21 -0.92 -0.08 -0.21 -0.23 1.58 -0.27 -0.29 0.04
14581 || orf19.4481 || MFALPHA || || Alpha factor mating pheromone precursor; three copies of pheromone that are proteolytically processed by Kex2p and possibly by Orf19.5851p; required for alpha cells to mate; expressed specifically in opaque phase MTLalpha/MTLalpha cells || 1 -1.11 1.19 -1.35 -0.18 -1.54 -0.07 -0.07 -0.05 0.30 1.98 -0.05 -0.16 -0.07
14582 || orf19.6580 || || || Protein of unknown function; Spider biofilm induced || 1 -0.06 -0.04 -0.27 -0.12 0.03 -0.59 0.04 0.10 -0.13 -0.42 -0.03 0.36 0.43 0.43 -0.22 -0.24