Index of /download/homology/best_hits

 Name                            Last modified      Size  Description
 Parent Directory                                     -   
 Calb_Scer_best_hits_Assem20.txt 12-Apr-2007 15:40   27K  
 Calb_Scer_best_hits_Assem21.txt 14-Nov-2008 15:21   34K  

To determine orthology assignments between C. albicans and S. cerevisiae, 
we used InParanoid (http://inparanoid.cgb.ki.se/), described in detail at 
http://candidagenome.org/download/homology/orthologs/Calb_Scer_by_inparanoid/.
 
For C. albicans proteins that did not have an ortholog that meets
the strict criteria used to define orthology with S. cerevisiae proteins, 
we used BLASTp, using the same parameters as were used by 
InParanoid (-F \"m S\" -M BLOSUM80) with an expectation value (E) of 1e-5 
to identify their best hit in the S. cerevisiae protein complement.  

These best hits data are available in the same format as the files containing
the ortholog data. The ortholog files are available at
http://candidagenome.org/download/homology/orthologs/Calb_Scer_by_inparanoid/

The following best hits files are available:

Calb_Scer_best_hits_Assem21.txt    - best hits (expectation value of 1e-5) for Assembly 21 proteins without orthologs

Calb_Scer_best_hits_Assem20.txt    - best hits (expectation value of 1e-5) for Assembly 20 proteins without orthologs


Assembly 21 best hits data (Calb_Scer_best_hits_Assem21.txt) are updated quaterly 
to ensure that the predictions are based on the most up-to-date information. 

Assembly 20 best hits data (Calb_Scer_best_hits_Assem20.txt) will not be regularly 
updated because Assembly 20 is considered archival. The Calb_Scer_best_hits_Assem20.txt
file with mappings generated in April 2007 will continue to be available from this directory.