References Added to CGD in the past week, since 2024-07-19

Newly curated references since 2024-07-19

Reference

Species

Genes Addressed

Casimiro-Ramos A, et al. (2024) Comparative Genomics of the First Resistant Candida auris Strain Isolated in Mexico: Phylogenomic and Pan-Genomic Analysis and Mutations Associated with Antifungal Resistance. J Fungi (Basel) 10(6)

C. auris

|ERG11 |FKS1

Ma Q, et al. (2024) Impact of secreted glucanases upon the cell surface and fitness of Candida albicans during colonisation and infection. Cell Surf 11:100128

C. albicans

|ENG1 |XOG1

Manzano JAH, et al. (2024) Globospiramine Exhibits Inhibitory and Fungicidal Effects against Candida albicans via Apoptotic Mechanisms. Biomolecules 14(6)

C. albicans

|ALS3 |C1_11790W_A |ERG11 |ERG24 |XOG1

Yang S, et al. (2024) In Vitro Activitiy of Rezafungin in Comparison with Anidulafungin and Caspofungin against Invasive Fungal Isolates (2017 to 2022) in China. J Fungi (Basel) 10(6)

C. albicans

|GSC1 |GSL1

C. glabrata

|FKS1

C. parapsilosis

|FKS1

Zhang Y, et al. (2024) DNA Damage Checkpoints Govern Global Gene Transcription and Exhibit Species-Specific Regulation on HOF1 in Candida albicans. J Fungi (Basel) 10(6)

C. albicans

|DUN1 |FKH2 |HMX1 |HOF1 |MCM1 |MRV6 |RAD53 |RAD9

Zhu X, et al. (2024) Mitochondrial Protease Oct1p Regulates Mitochondrial Homeostasis and Influences Pathogenicity through Affecting Hyphal Growth and Biofilm Formation Activities in Candida albicans. J Fungi (Basel) 10(6)

C. albicans

|ALS1 |ALS3 |ECE1 |FTR1 |HWP1 |MP65 |OCT1 |RBT5

Jiang Z, et al. (2014) Design, synthesis and antifungal activity of novel triazole derivatives containing substituted 1,2,3-triazole-piperdine side chains. Eur J Med Chem 82:490-7

C. albicans

|ERG11

Rawal MK, et al. (2014) Jatrophanes from Euphorbia squamosa as potent inhibitors of Candida albicans multidrug transporters. J Nat Prod 77(12):2700-6

C. albicans

|CDR1 |MDR1

Srivastava VK, et al. (2014) A systematic analysis reveals an essential role for high-affinity iron uptake system, haemolysin and CFEM domain-containing protein in iron homoeostasis and virulence in Candida glabrata. Biochem J 463(1):103-14

C. glabrata

|AFT1 |AFT2 |CCC2 |FET3 |FET4 |FRE6 |FTR1 |HLP |HMX1 |SSR1 |YFH1

Toth A, et al. (2014) Secreted Candida parapsilosis lipase modulates the immune response of primary human macrophages. Virulence 5(4):555-62

C. parapsilosis

|LIP1 |LIP2

Kolaczkowska A, et al. (2013) Differential expression of the Candida glabrata CgRTA1 and CgRSB1 genes in response to various stress conditions. Biochem Biophys Res Commun 432(1):169-74

C. glabrata

|PDR1 |RSB1 |RTA1

Ota KV and McGowan KL (2012) Declining incidence of candidemia in a tertiary inpatient pediatric population. J Clin Microbiol 50(3):1048-50

Chai X, et al. (2011) Design, synthesis and molecular docking studies of novel triazole as antifungal agent. Eur J Med Chem 46(7):3167-76

C. albicans

|ERG11

Fu Z, et al. (2011) Combination of baicalein and Amphotericin B accelerates Candida albicans apoptosis. Biol Pharm Bull 34(2):214-8

C. albicans

|MCA1

Lan D, et al. (2011) Optimal production and biochemical properties of a lipase from Candida albicans. Int J Mol Sci 12(10):7216-37

C. albicans

|LIP10

References automatically added to CGD since 2024-07-19
(possibly not yet curated)

Reference

Species

Genes Addressed

Andres MT, et al. (2024) The Antimicrobial Activity of Human Defensins at Physiological Non-Permeabilizing Concentrations Is Caused by the Inhibition of the Plasma Membrane H(+)-ATPases. Int J Mol Sci 25(13)

C. albicans

|PMA1 |TOK1

Boukhira S, et al. (2024) The chemical composition and the preservative, antimicrobial, and antioxidant effects of Thymus broussonetii Boiss. essential oil: an in vitro and in silico approach. Front Chem 12:1402310

C. albicans

|CYP5 |ERG11

Conway TP, et al. (2024) Overlapping coactivator function is required for transcriptional activation by the Candida glabrata Pdr1 transcription factor. Genetics

C. glabrata

|CDR1 |PDR1 |SNF2

Guinea J, et al. (2024) Fluconazole-resistant Candida parapsilosis: fast detection of the Y132F ERG11p substitution, and a proposed microsatellite genotyping scheme. Clin Microbiol Infect

C. parapsilosis

|ERG11

Ismail SHH, et al. (2024) Decoding host cell interaction- and fluconazole-induced metabolic alterations and drug resistance in Candida auris. Mycologia :1-21

C. auris

|CDR1 |ERG11

Raj K, et al. (2024) Decoding the role of oxidative stress resistance and alternative carbon substrate assimilation in the mature biofilm growth mode of Candida glabrata. BMC Microbiol 24(1):128

C. glabrata

|COF1 |ERG11 |ERG9 |ICL1 |MLS1 |NTH1 |PCK1 |TEF3

Wang H, et al. (2024) Activity of thonningianin A against Candida albicans in vitro and in vivo. Appl Microbiol Biotechnol 108(1):96

C. albicans

|MCA1

Wang L, et al. (2024) A novel quantitative double antigen sandwich ELISA for detecting total antibodies against Candida albicans enolase 1. Eur J Clin Microbiol Infect Dis

C. albicans

|ENO1

Amran AI, et al. (2023) Enolase in Meyerozyma guilliermondii strain SO: Sequential and structural insights of MgEno4581 as a putative virulence factor and host-fungal interactions through comprehensive in silico approaches. Microb Pathog 176:106025

C. albicans

|ENO1

Askari F, et al. (2023) Phosphatidylinositol 3-phosphate regulates iron transport via PI3P-binding CgPil1 protein. Cell Rep 42(8):112855

C. glabrata

|FTR1 |PIL1 |VPS34

Feng J, et al. (2023) Corrigendum to <'CaTip41 regulates protein phosphatase 2A activity, CaRad53 deactivation and the recovery of DNA damage-induced filamentation to yeast form in Candida albicans'>. FEMS Yeast Res 23

C. albicans

|RAD53 |TIP41

Liu L, et al. (2023) Novel spiro[pyrrolidine-2,3'-quinoline]-2'-one derivatives containing piperazine fragment as potential chitin synthase inhibitors and antifungal agents: Design, synthesis and biological evaluation. Eur J Med Chem 260:115777

C. albicans

|CHS2

Liu Z, et al. (2023) Biosensor-Enabled Discovery of CaERG6 Inhibitors and Their Antifungal Mode of Action against Candida albicans. ACS Infect Dis 9(4):785-800

C. albicans

|ERG6

Piao J, et al. (2023) Quantitatively detecting Candida albicans enolase1 with a one-step double monoclonal antibody sandwich ELISA assay. Front Microbiol 14:1078709

C. albicans

|ENO1

de Morais MC, et al. (2023) Synthetic Cinnamides and Cinnamates: Antimicrobial Activity, Mechanism of Action, and In Silico Study. Molecules 28(4)

C. albicans

|HOS2 |RPD3

Abdoli M, et al. (2022) Benzenesulfonamides Incorporating Hydantoin Moieties Effectively Inhibit Eukaryoticand Human Carbonic Anhydrases. Int J Mol Sci 23(22)

C. glabrata

|NCE103

Bachtiar BM, et al. (2022) Validation of RNA Aptamer Probes to Image Candida albicans in Paraffin-Embedded Sections of Wistar Rat Tongue. Eur J Dent 16(3):543-548

C. albicans

|APT1

Bhakt P, et al. (2022) The SET-domain protein CgSet4 negatively regulates antifungal drug resistance via the ergosterol biosynthesis transcriptional regulator CgUpc2a. J Biol Chem 298(10):102485

C. glabrata

|ERG3 |ERG4 |ERG5 |PDR1 |UPC2A

Carradori S, et al. (2022) Azole-Based Compounds That Are Active against Candida Biofilm: In Vitro, In Vivo and In Silico Studies. Antibiotics (Basel) 11(10)

C. glabrata

|NCE103

Clemente de Moraes D, et al. (2022) Effects of beta-lapachone and beta-nor-lapachone on multidrug efflux transporters and biofilms of Candida glabrata. Bioorg Med Chem 63:116749

C. glabrata

|CDR1 |PDH1

Gao A, et al. (2022) Machine-learning-based virtual screening to repurpose drugs for treatment of Candida albicans infection. Mycoses 65(8):794-805

C. albicans

|GSC1 |GSL1

Khatoon R, et al. (2022) Genomic landscape of the DHA1 family in Candida auris and mapping substrate repertoire of CauMdr1. Appl Microbiol Biotechnol 106(21):7085-7097

C. auris

|MDR1

Mirza A, et al. (2022) Epidemiology and Risk Factors of Candidemia Among Hospitalized Patients in a Turkish Tertiary Care Hospital. Clin Lab 68(1)

C. albicans

|SES1

Motta EP, et al. (2022) The Anti-Virulence Effect of Vismia guianensis against Candida albicans and Candida glabrata. Antibiotics (Basel) 11(12)

C. albicans

|CYP5 |ERG11

Pata J, et al. (2022) Production and Purification of a GFP-Tagged ABC Transporter CaCdr1p. Methods Mol Biol 2507:175-185

C. albicans

|CDR1

Sharma S, et al. (2022) Spontaneous Suppressors against Debilitating Transmembrane Mutants of CaMdr1 Disclose Novel Interdomain Communication via Signature Motifs of the Major Facilitator Superfamily. J Fungi (Basel) 8(5)

C. albicans

|GYP2 |MDR1

Silva AFD, et al. (2022) Anti-Candida albicans Activity of Ononin and Other Secondary Metabolites from Platonia Insignis MART. Metabolites 12(11)

C. albicans

|CYP5 |ERG11

Battu A, et al. (2021) An Assay to Determine NAD(P)H: Quinone Oxidoreductase Activity in Cell Extracts from Candida glabrata. Bio Protoc 11(21):e4210

C. glabrata

|PST2 |RFS1

Jakab A, et al. (2021) The Negative Effect of Protein Phosphatase Z1 Deletion on the Oxidative Stress Tolerance of Candida albicans Is Synergistic with Betamethasone Exposure. J Fungi (Basel) 7(7)

C. albicans

|PPZ1

Liang G, et al. (2021) Dynamic regulation of membrane integrity to enhance l-malate stress tolerance in Candida glabrata. Biotechnol Bioeng 118(11):4347-4359

C. glabrata

|YAP3 |YAP3b

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To cite CGD, please use the following reference: Skrzypek MS, Binkley J, Binkley G, Miyasato SR, Simison M, Sherlock G (2017). The Candida Genome Database (CGD): incorporation of Assembly 22, systematic identifiers and visualization of high throughput sequencing data. Nucleic Acids Res 45 (D1); D592-D596; see How to cite CGD.