About CGD

This is the home of the Candida Genome Database, a resource for genomic sequence data and gene and protein information for Candida albicans and related species. CGD is based on the Saccharomyces Genome Database and is funded by the National Institute of Dental & Craniofacial Research at the US National Institutes of Health.

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New and Noteworthy

Major update of the C. albicans genome sequence at CGD

We have released a major sequence update for C. albicans SC5314 (Assembly 22, version s06-m01-r01). Based on reanalysis by CGD of all available sequence data, the update affects more than 300 features, correcting many ORF translation errors and resolving many sequence ambiguities. The specific sequence changes can be viewed on our Chromosome History pages. (Posted February 2, 2016)

CGD Curation News

Updates to C. glabrata genome annotation

Multiple C. glabrata gene models were updated based on gene expression analysis conducted by Linde et al. (2015). 4,994 features were affected: 107 new features were added, including 49 protein-coding genes and 58 non-coding RNAs; 4 ORFs were deleted; the sequences for 132 features were extended and 10 shortened; 15 features were split to create 35 new features; 2 features were merged to create 1 new feature; 4,819 5-prime UTRs and 4,828 3-prime UTRs were added; The intron/exon structure was modified for 60 features; splice variants were identified for 16 features. For a list of updates, see Supplementary Table. (Posted April 15, 2015)

Assembly 22 of the C. albicans genome sequence

We are pleased to announce that Assembly 22 of the C. albicans SC5314 genome sequence has now become available at CGD, fully integrated into the CGD environment. Assembly 22 (A22) is described in Muzzey D., et al. (2013) Assembly of a phased, diploid Candida albicans genome facilitates allele-specific measurements and provides a simple model for repeat and indel structure. Genome Biol. 2013 Sep 11;14(9):R97.

Taking advantage of next-generation sequencing and achieving nearly 700-fold coverage, this phased, diploid assembly permits more sensitive, allele-specific analysis of the genome structure and funcion. A22 supersedes the previous Assembly 21 as the default genome sequence for C. albicans SC5314. All the previous assemblies remain available at CGD's download pages. (Posted June 27, 2014)

Introducing GeneXplorer for CGD

We have implemented GeneXplorer, a web tool for browsing and analysis of expression datasets and, so far, we have added microarray datasets from over 30 publications already archived at CGD. Each of those publication is linked via an icon to a GeneXplorer-generated web page that shows a colorimetric image of the clustered expression profiles. These images are zoomable and clickable (click on any profile to see the expression patterns of the most similarly or dissimilarly expressed genes). The publications are also linked (via ) to a downloadable data file in the pcl format. We are focusing our efforts on the microarray datasets and more publications are added to GeneXplorer every week. (Posted March 11, 2014)

Archived News

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