| Reference | Literature Topic | Genes Addressed |
|---|
Alonso-Monge R, et al. (2010) The Sko1 protein represses the yeast-to-hypha transition and regulates the oxidative stress response in Candida albicans. Fungal Genet Biol 47(7):587-601
| Genomic expression study | |AGP2 |ALS2 |ARA1 |ASR1 |ASR2 |ATF1 |BRG1 |CEK1 |CSP37 |DDR48 |EBP1 |ECE1 |FGR51 |FRE7 |MORE |
Coenye T (2010) Response of sessile cells to stress: from changes in gene expression to phenotypic adaptation. FEMS Immunol Med Microbiol 59(3):239-52
| Genomic expression study |
|
Epp E, et al. (2010) Forward genetics in Candida albicans that reveals the Arp2/3 complex is required for hyphal formation, but not endocytosis. Mol Microbiol 75(5):1182-98
| Genomic expression study | |ALS10 |ALS3 |ARP2 |ARP3 |BMT8 |CBP1 |CDC39 |CIP1 |DCK1 |ECE1 |ERG1 |ERG10 |ERG11 |ERG251 |MORE |
Epp E, et al. (2010) Reverse genetics in Candida albicans predicts ARF cycling is essential for drug resistance and virulence. PLoS Pathog 6(2):e1000753
| Comparative genomic hybridization | |ADA2 |AGE3 |ALS1 |BEM2 |CDR1 |CRH11 |CSH1 |DDR48 |ECM331 |ERG11 |FGR22 |GAL10 |GCN5 |ITR1 |MORE |
Gamarra S, et al. (2010) Mechanism of the synergistic effect of amiodarone and fluconazole in Candida albicans. Antimicrob Agents Chemother 54(5):1753-61
| Genomic expression study | |ACE2 |CCH1 |CCN1 |CDR1 |CLB2 |CMD1 |CMP1 |CNB1 |CRZ1 |ERG1 |ERG11 |ERG2 |ERG24 |ERG3 |MORE |
Gunasekera A, et al. (2010) Identification of GIG1, a GlcNAc-induced gene in C. albicans needed for normal sensitivity to the chitin synthase inhibitor nikkomycin z. Eukaryot Cell
| Genomic expression study | |CHA1 |DAC1 |DDR48 |GAL1 |GAL10 |GAL7 |GAP4 |GIG1 |HGT12 |HGT2 |HGT7 |HXK1 |HXT5 |NAG1 |MORE |
Hernaez ML, et al. (2010) Identification of Candida albicans exposed surface proteins in vivo by a rapid proteomic approach. J Proteomics 73(7):1404-9
| Large-scale protein localization | |ACT1 |ADH1 |ATP2 |BGL2 |CEF3 |CHT3 |COI1 |DDR48 |EFT2 |EGD2 |ENG1 |ENO1 |FET99 |GAP1 |MORE |
Holcombe LJ, et al. (2010) Pseudomonas aeruginosa secreted factors impair biofilm development in Candida albicans. Microbiology 156(Pt 5):1476-86
| Comparative genomic hybridization | |ALS1 |ALS2 |ALS3 |ALS4 |ALS5 |ALS6 |ALS7 |ALS9 |BCR1 |CDR1 |CDR2 |CHK1 |CPH1 |EAP1 |MORE |
Kelly J and Kavanagh K (2010) Proteomic analysis of proteins released from growth-arrested Candida albicans following exposure to caspofungin. Med Mycol 48(4):598-605
| Large-scale protein detection | |ADH1 |CDC19 |CIT1 |ENO1 |FBA1 |GND1 |GPM1 |PGK1 |TAL1 |TDH3 |XOG1 |orf19.2137 |orf19.3499 |
Kravets A, et al. (2010) Widespread occurrence of dosage compensation in Candida albicans. PLoS One 5(6):e10856
| Genomic expression study | |ACH1 |CAG1 |CAR1 |CTA24 |GAP6 |GDS1 |GLR1 |HIS1 |MDJ1 |PGA37 |PRE1 |PUT1 |RPO26 |SEC14 |MORE |
Lavoie H, et al. (2010) Evolutionary tinkering with conserved components of a transcriptional regulatory network. PLoS Biol 8(3):e1000329
| Large-scale protein modification, Genomic co-immunoprecipitation study | |CBF1 |CDC28 |CLN3 |FHL1 |FKH2 |HHT1 |HHT2 |HHT21 |HMO1 |IFH1 |MCM1 |PCL2 |PCL5 |RAP1 |MORE |
Lis M, et al. (2010) Antimicrobial peptide MUC7 12-mer activates the calcium/calcineurin pathway in Candida albicans. FEMS Yeast Res 10(5):579-86
| Genomic expression study | |CFL2 |CFL4 |CFL5 |CMP1 |CRZ1 |CRZ2 |ECM331 |FET3 |FET34 |FGR22 |FRE30 |FTR2 |IML2 |ISU1 |MORE |
Lopes da Rosa J, et al. (2010) Histone acetyltransferase Rtt109 is required for Candida albicans pathogenesis. Proc Natl Acad Sci U S A 107(4):1594-9
| Genomic expression study | |ALS1 |DDR48 |HHO1 |HTA3 |IFE2 |PCK1 |RAD51 |RTT109 |SOD5 |
Mochon AB, et al. (2010) Serological profiling of a Candida albicans protein microarray reveals permanent host-pathogen interplay and stage-specific responses during candidemia. PLoS Pathog 6(3):e1000827
| Large-scale protein detection | |ALS1 |ALS3 |ALS5 |BGL2 |CDC19 |CDC24 |ECE1 |ENO1 |GAP1 |HSP90 |HWP1 |HYR1 |INT1 |PGK1 |MORE |
Nailis H, et al. (2010) Transcriptional response to fluconazole and amphotericin B in Candida albicans biofilms. Res Microbiol 161(4):284-92
| Comparative genomic hybridization, Genomic expression study | |CDR1 |CDR2 |ERG1 |ERG11 |ERG25 |ERG3 |KRE1 |MDR1 |SKN1 |
Noble SM, et al. (2010) Systematic screens of a Candida albicans homozygous deletion library decouple morphogenetic switching and pathogenicity. Nat Genet 42(7):590-8
| Large-scale phenotype analysis | |HET1 |HSX11 |MTS1 |SLD1 |
O'Connor L, et al. (2010) Differential filamentation of Candida albicans and C. dubliniensis is governed by nutrient regulation of UME6 expression. Eukaryot Cell
| Genomic expression study | |UME6 |
Oh J, et al. (2010) A universal TagModule collection for parallel genetic analysis of microorganisms. Nucleic Acids Res 38(14):e146
| Large-scale phenotype analysis | |APM1 |CMD1 |DBP7 |ERG11 |ERG2 |FGR50 |GDB1 |KSP1 |NBN1 |NCP1 |NOP4 |POL2 |RPT5 |SEC8 |MORE |
Rosenbach A, et al. (2010) Adaptations of Candida albicans for growth in the mammalian intestinal tract. Eukaryot Cell 9(7):1075-86
| Comparative genomic hybridization | |ADH5 |ADR1 |AFG3 |ALA1 |ALS1 |ALS10 |CAN2 |CAP1 |CDC60 |CDR1 |CPH2 |CTN3 |DEF1 |DFG16 |MORE |
Seedhouse SJ, et al. (2010) The Privileged Chemical Space Predictor (pcsp): A computer program that identifies privileged chemical space from screens of modularly assembled chemical libraries. Bioorg Med Chem Lett 20(4):1338-1343
| Computational analysis | |LSU |
Sellam A, et al. (2010) Experimental annotation of the human pathogen Candida albicans coding and noncoding transcribed regions using high-resolution tiling arrays. Genome Biol 11(7):R71
| Genomic expression study | |CPR3 |FBP1 |FLO9 |GAL102 |IFM3 |OPT9 |RFC52 |RPP0 |RPT1 |SEC6 |TER1 |TLO34 |orf19.1026.1 |orf19.1075.1 |MORE |
Sellam A, et al. (2010) Role of transcription factor CaNdt80p in cell separation, hyphal growth, and virulence in Candida albicans. Eukaryot Cell 9(4):634-44
| Genomic expression study | |CHT3 |NDT80 |SUN41 |orf19.513 |
Sorgo AG, et al. (2010) Mass spectrometric analysis of the secretome of Candida albicans. Yeast 27(8):661-72
| Large-scale protein detection | |ALS3 |ALS4 |APE2 |BGL2 |CHT1 |CHT2 |CHT3 |COI1 |CRH11 |CSA2 |CYP5 |DAG7 |ECM33 |ENG1 |MORE |
Spiering MJ, et al. (2010) Comparative transcript profiling of Candida albicans and Candida dubliniensis identifies SFL2, a C. albicans gene required for virulence in a reconstituted epithelial infection model. Eukaryot Cell 9(2):251-65
| Genomic expression study | |ALS3 |ECE1 |HSP104 |HSP12 |HSP60 |HSP70 |HSP78 |HWP1 |HYR1 |ICL1 |IHD1 |NOP1 |PCK1 |PMT1 |MORE |
Vediyappan G, et al. (2010) Interaction of Candida albicans biofilms with antifungals: transcriptional response and binding of antifungals to beta-glucans. Antimicrob Agents Chemother 54(5):2096-111
| Genomic expression study | |ALS3 |HWP1 |
Wang YC, et al. (2010) Global screening of potential Candida albicans biofilm-related transcription factors via network comparison. BMC Bioinformatics 11:53
| Computational analysis | |ADR1 |CPH1 |EFG1 |EFH1 |FGR15 |FHL1 |GCN4 |INO4 |MCM1 |MET28 |MNL1 |RAP1 |RPN4 |SKN7 |MORE |
Wapinski I, et al. (2010) Gene duplication and the evolution of ribosomal protein gene regulation in yeast. Proc Natl Acad Sci U S A 107(12):5505-10
| Genomic expression study | |FHL1 |
Zacchi LF, et al. (2010) Mds3 regulates morphogenesis in Candida albicans through the TOR pathway. Mol Cell Biol 30(14):3695-710
| Genomic expression study | |CDC19 |ECE1 |GAP2 |HWP1 |MDS3 |RBP1 |RIM101 |RPS26A |SIT4 |TEF1 |TOR1 |
Angiolella L, et al. (2009) Localisation of Bgl2p upon antifungal drug treatment in Candida albicans. Int J Antimicrob Agents 33(2):143-8
| Large-scale protein detection | |BGL2 |GPM1 |GPM2 |RHD3 |
Arbour M, et al. (2009) Widespread occurrence of chromosomal aneuploidy following the routine production of Candida albicans mutants. FEMS Yeast Res 9(7):1070-7
| Genomic expression study | |CPH1 |CWT1 |CYR1 |EFG1 |FUN31 |MKC1 |NRG1 |RAS1 |RFG1 |SSN6 |SST2 |STE4 |TAC1 |VMA22 |