Genome-wide Analysis papers

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Genome-wide AnalysisProteome-wide Analysis
Comparative genomic hybridizationLarge-scale protein detection
Computational analysisLarge-scale protein interaction
Genomic co-immunoprecipitation studyLarge-scale protein localization
Genomic expression studyLarge-scale protein modification
Large-scale genetic interactionOther large-scale proteomic analysis
Large-scale phenotype analysis 
Other genomic analysis 

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ReferenceLiterature TopicSpeciesGenes Addressed
Chow EWL, et al. (2024) Genome-wide profiling of piggyBac transposon insertion mutants reveals loss of the F(1) F(0) ATPase complex causes fluconazole resistance in Candida glabrata. Mol Microbiol
CGD Papers Entry  Pubmed Entry  
Genomic expression study, Large-scale phenotype analysisC. glabrata |ATP22 |ATP3 |CDR1 |PDH1 |PDR1 |SNQ2
Misas E, et al. (2024) Genomic description of acquired fluconazole- and echinocandin-resistance in patients with serial Candida glabrata isolates. J Clin Microbiol :e0114023
CGD Papers Entry  Pubmed Entry  
Other genomic analysisC. glabrata |FKS1 |FKS2 |PDR1
Pavesic MW, et al. (2024) Calcineurin-dependent contributions to fitness in the opportunistic pathogen Candida glabrata. mSphere 9(1):e0055423
CGD Papers Entry  Pubmed Entry  
Large-scale phenotype analysisC. glabrata |ALG5 |ALG6 |ALG8 |APL2 |APS1 |ARF1 |CNB1 |CRZ1 |DCW1 |FKS1 |FLC2 |INP53 |LAS21 |PDR1 |MORE
Teng W, et al. (2024) Heat Shock Protein SSA1 Enriched in Hypoxic Secretome of Candida albicans Exerts an Immunomodulatory Effect via Regulating Macrophage Function. Cells 13(2)
CGD Papers Entry  Pubmed Entry  
Large-scale protein detectionC. albicans |HSP70
Wang Y and Xu J (2024) Associations between Genomic Variants and Antifungal Susceptibilities in the Archived Global Candida auris Population. J Fungi (Basel) 10(1)
CGD Papers Entry  Pubmed Entry  
Other genomic analysisC. auris |ERG11 |FKS1
Abdulghani M, et al. (2023) Opaque Cell Specific Proteome of Candida albicans ATCC 10231. Med Mycol
CGD Papers Entry  Pubmed Entry  
Other large-scale proteomic analysisC. albicans |AGE3 |ALS1 |ATP1 |ATP16 |ATP3 |ATP7 |CCP1 |CCS1 |COX6 |CSH1 |GCS1 |GPX2 |GPX3 |GTT11 |MORE
Alam F, et al. (2023) Pseudomonas aeruginosa increases the susceptibility of Candida albicans to amphotericin B in dual-species biofilms. J Antimicrob Chemother
CGD Papers Entry  Pubmed Entry  Web Supplement  Data  
Genomic expression studyC. albicans |CAP1 |ERG6 |SOD2 |UPC2
Alings F, et al. (2023) Ncs2* mediates in vivo virulence of pathogenic yeast through sulphur modification of cytoplasmic transfer RNA. Nucleic Acids Res
CGD Papers Entry  Pubmed Entry  
Genomic expression studyC. albicans |NCS2 |tE(UUC)1 |tE(UUC)2 |tE(UUC)3 |tE(UUC)4 |tE(UUC)5 |tE(UUC)6 |tE(UUC)7 |tK(UUU)1 |tK(UUU)2 |tK(UUU)3 |tK(UUU)4 |tK(UUU)5
Balla N, et al. (2023) Total transcriptome analysis of Candida auris planktonic cells exposed to tyrosol. AMB Express 13(1):81
CGD Papers Entry  Pubmed Entry  
Genomic expression studyC. auris |CAP1 |HSP78 |SOD4
Ben Abid F, et al. (2023) Molecular characterization of Candida auris outbreak isolates in Qatar from COVID-19 patients reveals the emergence of isolates resistant to three classes of antifungal drugs. Clin Microbiol Infect
CGD Papers Entry  Pubmed Entry  
Other genomic analysisC. auris |CDR1 |CDR2 |CIS2 |ERG11 |ERG3 |ERG4 |ERG5 |FKS1 |SNQ2 |STE6 |TAC1b
Brandt P, et al. (2023) High-Throughput Profiling of Candida auris Isolates Reveals Clade-Specific Metabolic Differences. Microbiol Spectr :e0049823
CGD Papers Entry  Pubmed Entry  
Genomic expression study, Large-scale phenotype analysisC. auris |B9J08_002974 |B9J08_003830 |B9J08_004062 |B9J08_004066 |B9J08_004188 |B9J08_004204 |B9J08_004243 |B9J08_004448 |B9J08_004538 |B9J08_004560 |B9J08_004893 |B9J08_005124 |B9J08_005570 |B9J08_005571 |MORE
C. albicans |JEN1 |JEN2 |TNA1
Case NT, et al. (2023) Respiration supports intraphagosomal filamentation and escape of Candida albicans from macrophages. mBio :e0274523
CGD Papers Entry  Pubmed Entry  
Large-scale phenotype analysisC. albicans |COR1 |MRP21 |SNF1
Chow EWL, et al. (2023) The transcription factor Rpn4 activates its own transcription and induces efflux pump expression to confer fluconazole resistance in Candida auris. MBio :e0268823
CGD Papers Entry  Pubmed Entry  Web Supplement  Data  
Genomic expression studyC. auris |CDR1 |MDR1 |MUB1 |RPN4 |UBR2
Cravener MV, et al. (2023) Reinforcement amid genetic diversity in the Candida albicans biofilm regulatory network. PLoS Pathog 19(1):e1011109
CGD Papers Entry  Pubmed Entry  
Genomic expression studyC. albicans |BRG1 |C2_05770W_A |EFG1 |RFX2 |UME6 |WOR3
Cui Y, et al. (2023) Systematic identification and characterization of five transcription factors mediating the oxidative stress response in Candida albicans. Microb Pathog 187:106507
CGD Papers Entry  Pubmed Entry  
Genomic expression studyC. albicans |CAP1 |DAL81 |DPB4 |SKN7 |STP2
Dong Y, et al. (2023) Reduction of histone proteins dosages increases CFW sensitivity and attenuates virulence of Candida albicans. Microbiol Res 279:127552
CGD Papers Entry  Pubmed Entry  
Genomic expression studyC. albicans |CHT2 |CHT3 |CRH11 |ERO1 |FAD1 |FAV3 |HHF1 |HHT21 |KAR2 |MNS1 |RHO1 |ROM2 |SAP9
Doss EM, et al. (2023) Characterization of endoplasmic reticulum-associated degradation in the human fungal pathogen Candida albicans. PeerJ 11:e15897
CGD Papers Entry  Pubmed Entry  Web Supplement  Data  
Large-scale protein detectionC. albicans |DOA10 |HRD1 |UBC7
Fletcher J, et al. (2023) Deletion of the Candida albicans TLO gene family using CRISPR-Cas9 mutagenesis allows characterisation of functional differences in alpha-, beta- and gamma- TLO gene function. PLoS Genet 19(12):e1011082
CGD Papers Entry  Pubmed Entry  
Genomic co-immunoprecipitation study, Genomic expression studyC. albicans |ALS3 |CTA2 |CTA24 |CTA26 |ECE1 |GAL4 |HSP30 |HWP1 |HYR1 |MED3 |OP4 |RBR1 |SKO1 |TLO1 |MORE
Gale AN, et al. (2023) Redefining pleiotropic drug resistance in a pathogenic yeast: Pdr1 functions as a sensor of cellular stresses in Candida glabrata. mSphere :e0025423
CGD Papers Entry  Pubmed Entry  Web Supplement  Data  
Large-scale phenotype analysisC. glabrata |ATP1 |ATP2 |CAGL0G00858g |CAGL0I07953g |CAGL0J00297g |CAGL0L03828g |CAGL0M11726g |CDR1 |CIN5 |DAP1 |ERG11 |HOG1 |KGD1 |KGD2 |MORE
Ganser C, et al. (2023) Filamentation and biofilm formation are regulated by the phase-separation capacity of network transcription factors in Candida albicans. PLoS Pathog 19(12):e1011833
CGD Papers Entry  Pubmed Entry  
Genomic expression studyC. albicans |BCR1 |BRG1 |EFG1 |FLO8
Goncalves B, et al. (2023) Sfl1 is required for Candida albicans biofilm formation under acidic conditions. Biochimie
CGD Papers Entry  Pubmed Entry  Web Supplement  Data  
Genomic expression studyC. albicans |AHR1 |BRG1 |SFL1 |TEC1 |TYE7 |WOR1
Guan G, et al. (2023) Glucose depletion enables Candida albicans mating independently of the epigenetic white-opaque switch. Nat Commun 14(1):2067
CGD Papers Entry  Pubmed Entry  
Large-scale protein detection, Genomic expression studyC. albicans |CEK1 |CEK2 |CPH1 |FIG1 |FUS1 |GPR1 |HGT12 |MFA1 |MFALPHA |STE2 |STE3 |TEC1 |WOR1
Guan G, et al. (2023) The Rfg1 and Bcr1 transcription factors regulate acidic pH-induced filamentous growth in Candida albicans. Microbiol Spectr :e0178923
CGD Papers Entry  Pubmed Entry  
Genomic expression studyC. albicans |BCR1 |C6_04340W_A |CFL11 |CYR1 |EFG1 |ENA2 |FLO8 |HGC1 |PHR1 |PHR2 |RBT5 |RFG1 |RIM101 |SLD1
Hu L, et al. (2023) A first-in-class inhibitor of Hsp110 molecular chaperones of pathogenic fungi. Nat Commun 14(1):2745
CGD Papers Entry  Pubmed Entry  
Genomic expression studyC. albicans |MSI3
Jiang L, et al. (2023) Transcriptional expression of PHR2 is positively controlled by the calcium signaling transcription factor Crz1 through its binding motif in the promoter. Microbiol Spectr :e0168923
CGD Papers Entry  Pubmed Entry  
Genomic co-immunoprecipitation studyC. albicans |CRZ1 |PHR2 |RIM101
Kumaraswamy M, et al. (2023) Comprehensive whole genome sequencing with hybrid assembly of multi-drug resistant Candida albicans isolate causing cerebral abscess. Curr Res Microb Sci 4:100180
CGD Papers Entry  Pubmed Entry  
Computational analysisC. auris |CDR2 |MDR1
C. albicans |CDR1 |CDR2 |CTA4 |ERG11 |GSC1 |GSL2 |MDR1 |MRR1 |MSH2 |PUP1 |RIM8 |SAP99 |TAC1
Lee CD, et al. (2023) Cell-type memory in a single-cell eukaryote requires the continuous presence of a specific transcription regulator. Proc Natl Acad Sci U S A 120(21):e2220568120
CGD Papers Entry  Pubmed Entry  Web Supplement  Data  
Genomic expression studyC. albicans |WOR1
Li S, et al. (2023) Structural Characterization, Cytotoxicity, and the Antifungal Mechanism of a Novel Peptide Extracted from Garlic (Allium sativa L.). Molecules 28(7)
CGD Papers Entry  Pubmed Entry  
Genomic expression studyC. albicans |CDR1 |CDR2
Li Y, et al. (2023) Whole genome analysis of echinocandin non-susceptible Candida Glabrata clinical isolates: a multi-center study in China. BMC Microbiol 23(1):341
CGD Papers Entry  Pubmed Entry  
Other genomic analysisC. glabrata |CAGL0E01353g |CAGL0H07007g |CAGL0K05313g |CAGL0M02145g |SUR2 |ZCF15
Luther CH, et al. (2023) Integrated analysis of SR-like protein kinases Sky1 and Sky2 links signaling networks with transcriptional regulation in Candida albicans. Front Cell Infect Microbiol 13:1108235
CGD Papers Entry  Pubmed Entry  
Computational analysis, Genomic expression studyC. albicans |ACE2 |C2_04360W_A |EFG1 |EFH1 |FLO8 |KIC1 |MOB1 |SKY1 |SKY2 |WOR1
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